Solubilization of unconjugated bilirubin by bile salts.
Freshly precipitated unconjugated bilirubin (UCB) is solubilized rapidly and to a large extent by the sodium salts of di- and trihydroxy bile acids. The solubilization effect depending on bile salt concentration, pH and ionic strength is based on micellar mechanisms.
D001647:Bile Acids and Salts; D001663:Bilirubin; D002784:Cholesterol; D006863:Hydrogen-Ion Concentration; D006880:Hydroxy Acids; D008823:Micelles; D010713:Phosphatidylcholines; D012995:Solubility
D001647:Bile Acids and Salts; D006880:Hydroxy Acids; D008823:Micelles; D010713:Phosphatidylcholines; D002784:Cholesterol; D001663:Bilirubin