Hepatocellular carcinoma: relation to alcohol, HB-antigen and alpha-fetoprotein.
Thirteen of 16 patients with primary cancer of the liver were heavy alcoholics. Fifty per cent of them had positive alpha-fetoprotein and 25% had HB-Ag in their blood. The association of alcoholism with cancer of the liver is thus very striking and hence alcohol should be proclaimed as a carcinogenic substance.
D001741:Black or African American; D000367:Age Factors; D000368:Aged; D000437:Alcoholism / Q000150:complications*; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000209:etiology*; D005260:Female; D005326:Fetal Proteins / Q000032:analysis*; D006505:Hepatitis / Q000150:complications; D006509:Hepatitis B / Q000150:complications; D006511:Hepatitis B Antigens / Q000032:analysis*; D006801:Humans; D005779:Immunodiffusion; D008103:Liver Cirrhosis / Q000150:complications; D008113:Liver Neoplasms / Q000150:complications / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D012737:Sex Factors; D000509:alpha-Fetoproteins / Q000032:analysis*
D005326:Fetal Proteins; D006511:Hepatitis B Antigens; D000509:alpha-Fetoproteins