Intra-amniotic urea and low-dose prostaglandin E2 for midtrimester termination.
The efficacy and morbidity of injecting a standard dose of urea (80 g.) and a lower dose of prostaglandin E2 (P.G.E2) (2-5 MG) than that used previously have been assesed in 110 patients. All aborted--in a mean time of 10 hours 41 minutes. The average inpatient stay was 3-3 days. 5 patients (4-5%) had a cervical laceration.
D000019:Abortifacient Agents / Q000008:administration & dosage* / Q000009:adverse effects; D000028:Abortion, Induced; D000293:Adolescent; D000328:Adult; D000653:Amniotic Fluid; D004357:Drug Synergism; D005260:Female; D005865:Gestational Age; D006801:Humans; D006982:Hypertonic Solutions; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011458:Prostaglandins E / Q000008:administration & dosage* / Q000009:adverse effects; D014508:Urea / Q000008:administration & dosage* / Q000009:adverse effects
D000019:Abortifacient Agents; D006982:Hypertonic Solutions; D011458:Prostaglandins E; D014508:Urea