Double-blind trial of glycerol therapy in early stroke.
The effects of intravenous glycerol and intravenous dextrose were compared using a double-blind trial in twenty-seven patients with acute stroke. Administration continued for up to 6 days. A standard scoring system was used for neurological evaluation. There was no difference in mortality or in improvement in neurological score between the two groups.
D000208:Acute Disease; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005947:Glucose / Q000008:administration & dosage / Q000627:therapeutic use; D005990:Glycerol / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007275:Injections, Intravenous; D009460:Neurologic Examination; D010919:Placebos; D013997:Time Factors
D010919:Placebos; D005947:Glucose; D005990:Glycerol