Practical experiences with flunitrazepam in anesthesia.
Flunitrazepam was used in general and local anesthesia. Little effect was noted on the respiratory and cardiovascular systems. In our patients there was an impressive period of amnesia and often we observed a central anticholinergic syndrome, which could be reversed by the use of physostigmine salicylate (0.04/kg body weight).
D000293:Adolescent; D000328:Adult; D000368:Aged; D000647:Amnesia / Q000139:chemically induced; D000765:Anesthesia, Conduction; D000768:Anesthesia, General; D000771:Anesthesia, Intravenous; D014151:Anti-Anxiety Agents / Q000378:metabolism / Q000494:pharmacology; D005069:Evaluation Studies as Topic; D005260:Female; D005445:Flunitrazepam / Q000378:metabolism / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D012119:Respiration / Q000187:drug effects
D014151:Anti-Anxiety Agents; D005445:Flunitrazepam