Relative efficacy of blood, urine, rectal swab, bone-marrow, and rose-spot cultures for recovery of Salmonella typhi in typhoid fever.
The recovery of Salmonella typhi from blood, rectal swab, urine, bone-marrow, and rose spots was compared in 62 patients with typhoid fever, most of whom had received some antibiotic therapy before presentation. S. typhi was isolated from culture of bone-marrow in 56 patients (90%); in contrast, S. typhi was recovered from blood in only 25 (40%), from stool in 23 (37%), and urine in 4 (7%). S. typhi was isolated from 24 (63%) of 38 patients who had rose-spot cultures. If culture sites had been limited to blood, stool, and urine, the bacteriological diagnosis would have been missed in 24 patients.
D001437:Bacteriuria / Q000382:microbiology; D001769:Blood / Q000382:microbiology; D001853:Bone Marrow / Q000382:microbiology; D046508:Culture Techniques; D004890:Erythema / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D012485:Salmonella typhi / Q000302:isolation & purification*; D012867:Skin / Q000382:microbiology; D013997:Time Factors; D014435:Typhoid Fever / Q000097:blood / Q000175:diagnosis / Q000382:microbiology*; D014556:Urine / Q000382:microbiology