IgE antibodies in patients allergic to rifampicin.
In sera of patients treated with rifampicin, who had episodes ascribable to rifampicin sensitization, IgE antibodies were found. These antibodies cross-react with rifamycin SV and with the chromophoric moiety of rifamycins, but not with the side chain of rifampicin.
D000906:Antibodies / Q000032:analysis*; D004342:Drug Hypersensitivity / Q000276:immunology*; D006636:Histamine Release; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D012293:Rifampin / Q000009:adverse effects* / Q000276:immunology; D012294:Rifamycins / Q000494:pharmacology
D000906:Antibodies; D012294:Rifamycins; D007073:Immunoglobulin E; D012293:Rifampin