The effects of temperature and pH variations on plaque production by different virulence types of myxoma virus.
Eight 'strains' of myxoma virus, spanning the complete spectrum of virulence, were tested for ability to produce plaques on rabbit kidney cells at varying temperatures and pH values. A positive correlation was found between virulence in rabbits and ability to produce plaques at supra-optimal temperature and at low pH.
D000818:Animals; D002460:Cell Line; D006863:Hydrogen-Ion Concentration; D007668:Kidney; D009233:Myxoma virus / Q000254:growth & development* / Q000472:pathogenicity; D011817:Rabbits; D013696:Temperature; D010948:Viral Plaque Assay; D014774:Virulence; D014779:Virus Replication