Pial arterial reactions to hyper- and hypocapnia: a dynamic experimental study in cats.
In 29 cats, the extent and time-course of the pial arterial reactions to hypo- and hypercapnia were studied by means of the skull-window technique. The typical, well-known dilatations and constrictions during hyper- and hypocapnia were seen. The latent period for dilatation after the beginning of CO2-inhalation was ca. 20 sec. There was no stable relation observable between vessel diameter and arterial carbon dioxide tension (paCO2). Diameter changes lagged behind CO2-changes, indicating that CO2 acts via metabolic regulation, probably extracellular pH.
D000792:Angiography; D000818:Animals; D001158:Arteries / Q000502:physiology; D002245:Carbon Dioxide / Q000097:blood*; D002415:Cats; D005260:Female; D006863:Hydrogen-Ion Concentration; D006935:Hypercapnia / Q000503:physiopathology*; D008297:Male; D010313:Partial Pressure; D010841:Pia Mater / Q000098:blood supply*; D014661:Vasoconstriction; D014664:Vasodilation
D002245:Carbon Dioxide