Immunogenetic factors in preeclampsia and eclampsia. Erythrocyte, histocompatibility, and Y-dependent antigens.
Determination of ABO and HL-A antigens and sex ratio of infants born to 46 women with preeclampsia or eclampsia, in comparison with normal controls, disclosed no predominant blood group, HL-A haplotype, or qualitative difference in maternal-fetal incompatibility. These results suggest that a link between immunologic mechanisms and the pathogenesis of toxemia syndromes, if present at all, must be associated with feto-placental tissue-specific antigens.
D000017:ABO Blood-Group System; D004461:Eclampsia / Q000235:genetics / Q000276:immunology*; D000939:Epitopes; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006649:Histocompatibility Antigens; D006801:Humans; D008297:Male; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000276:immunology*; D011225:Pre-Eclampsia / Q000235:genetics / Q000276:immunology*; D011247:Pregnancy; D012744:Sex Ratio
D000017:ABO Blood-Group System; D000939:Epitopes; D006649:Histocompatibility Antigens