Passovoy factor: A hitherto unrecognised factor necessary for haemostasis.
A moderate bleeding diathesis transmitted as an autosomal dominant was found in five members of four generations of the same family. The affected patients had prolonged partial thromboplastin-times and normal levels of all the known clotting-factors. The haemorrhagic diathesis was attributed to a deficiency of a hitherto unrecognised coagulation factor--i.e., the Passovoy facto.
D000328:Adult; D000536:Aluminum Hydroxide; D001779:Blood Coagulation Factors; D001780:Blood Coagulation Tests; D002648:Child; D003677:Deficiency Diseases / Q000150:complications; D005260:Female; D006474:Hemorrhagic Disorders / Q000209:etiology / Q000235:genetics*; D006487:Hemostasis; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D013925:Thromboplastin / Q000032:analysis
D001779:Blood Coagulation Factors; D000536:Aluminum Hydroxide; D013925:Thromboplastin