Molecular properties of the adrenergic alpha receptor. 2. Optimum covalent inhibition by two different prototypes of polyamine disulfides.
D000317:Adrenergic alpha-Antagonists / Q000138:chemical synthesis*; D000818:Animals; D004220:Disulfides / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D004837:Epinephrine / Q000037:antagonists & inhibitors; D006168:Guinea Pigs; D006339:Heart Rate / Q000187:drug effects; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D009200:Myocardial Contraction / Q000187:drug effects; D009638:Norepinephrine / Q000037:antagonists & inhibitors; D011073:Polyamines / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D011942:Receptors, Adrenergic, alpha / Q000378:metabolism; D013329:Structure-Activity Relationship
D000317:Adrenergic alpha-Antagonists; D004220:Disulfides; D011073:Polyamines; D011942:Receptors, Adrenergic, alpha; D009638:Norepinephrine; D004837:Epinephrine