Nicafenine, a new analgesic. I. Synthesis and physicochemical properties.
The synthesis of 2-[(7-chloro-4-quinolyl)-amino] benzoic acid 3-pyridine carboxamide-N-ethyl ester (nicafenine) was carried out by a new method using isatoic anhydride. The IR, NMR, MS and UV spectrophotometric studies are described, together with the characteristics of this compound.
D000700:Analgesics / Q000138:chemical synthesis* / Q000302:isolation & purification; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002855:Chromatography, Thin Layer; D005897:Glafenine / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D062367:ortho-Aminobenzoates / Q000138:chemical synthesis*
D000700:Analgesics; D062367:ortho-Aminobenzoates; D005897:Glafenine; C023803:nicafenine