Further experience with a capillary tube pregnancy test.
Further evaluation of the nonrefrigerated capillary tube pregnancy test is presented. A 127-mm by 2-mm glass capillary tube containing lyophilized antibody to human chorionic gonadotropin and latex indicator particles is used. Urine is drawn into the tube by capillary action; then, the tube is tilted to allow the urine to dissolve the antibody and to suspend the latex particles. The test results are read after a one-hour incubation period. Test results were evaluated against histopathologic and clinical data. Special efforts were made to stress the false-positive rate of the test by tripling the number of negative cases and doubling the sample size. A 99.82% agreement, a 0.18% false-negative rate and a 0% false-positive rate were obtained. In 52 confirmed pregnancies, the more sensitive capillary test detected human chorionic gonadotropin, whereas the commercial tests did not. Human chorionic gonadotropin was also detected one week earlier than reported in the first series.
D000906:Antibodies; D006063:Chorionic Gonadotropin / Q000276:immunology; D005189:False Positive Reactions; D005260:Female; D005612:Freeze Drying; D006801:Humans; D011247:Pregnancy; D011258:Pregnancy Tests / Q000379:methods*
D000906:Antibodies; D006063:Chorionic Gonadotropin