Chronic pancreatitis, sclerosing cholangitis, and sicca complex in two siblings.
A new syndrome of chronic pancreatitis, sclerosing cholangitis, sicca complex, and other features was found in a brother and sister. Leucocyte-migration inhibition in the presence of a bile antigen in both patients suggested that immune mechanisms may be involved.
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002648:Child; D002758:Cholangiography; D002761:Cholangitis / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000235:genetics*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008111:Liver Function Tests; D008297:Male; D010179:Pancreas / Q000473:pathology; D010195:Pancreatitis / Q000150:complications / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D012598:Sclerosis / Q000150:complications / Q000235:genetics; D012859:Sjogren's Syndrome / Q000150:complications / Q000235:genetics*