Studies on the effect of Fenchlorphos on postirradiation changes of serum proteins and nucleic acids content in rat liver.
The effect of Fenchlorphos on postirradiation changes of serum protein levels and nucleic acid content in rat liver were investigated. It was found that this compound significantly decreases postirradiation changes in serum proteins, properdin level and nucleic acid content in rat liver. An important role of these phenomena in radioprotective action of Fenchlorphos is suggested.
D000510:Alpha-Globulins / Q000378:metabolism; D000818:Animals; D001609:Beta-Globulins / Q000378:metabolism; D001798:Blood Proteins / Q000378:metabolism / Q000528:radiation effects*; D004247:DNA / Q000378:metabolism; D005260:Female; D008099:Liver / Q000187:drug effects / Q000528:radiation effects*; D009696:Nucleic Acids / Q000528:radiation effects*; D009946:Organothiophosphorus Compounds / Q000494:pharmacology*; D011414:Properdin / Q000032:analysis; D012313:RNA / Q000378:metabolism; D011830:Radiation Effects; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D051381:Rats; D012709:Serum Albumin / Q000378:metabolism; D013997:Time Factors; D005719:gamma-Globulins / Q000378:metabolism
D000510:Alpha-Globulins; D001609:Beta-Globulins; D001798:Blood Proteins; D009696:Nucleic Acids; D009946:Organothiophosphorus Compounds; D011837:Radiation-Protective Agents; D012709:Serum Albumin; D005719:gamma-Globulins; D011414:Properdin; D012313:RNA; D004247:DNA