Relative tissue distribution of radioactivity in rats with endocrine "autonomous" breast carcinomas after 3H-,99mTc-, and 64Cu-bleomycin.
The localization of 64Cu-, 3H-, and 99mTc-labeled bleomycin was studied in tissues of Fisher rats bearing an endocrine autonomous breast tumor. The 64Cu-bleomycin showed a greater uptake than 3H- and 99mTc-bleomycin in the breast tumor at all time intervals studied, from 2 to 72 hr after the tracer. This same differential uptake was shared by the liver and kidney.
D000818:Animals; D001761:Bleomycin / Q000378:metabolism; D003300:Copper; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008325:Mammary Neoplasms, Experimental / Q000175:diagnosis* / Q000378:metabolism; D009368:Neoplasm Transplantation; D011868:Radioisotopes; D011877:Radionuclide Imaging; D051381:Rats; D013667:Technetium; D013997:Time Factors; D014316:Tritium
D011868:Radioisotopes; D014316:Tritium; D001761:Bleomycin; D013667:Technetium; D003300:Copper