Effects of stannous fluoride and tiodonium chloride on dental plaque in rats.
Rats with six-day-old plaque were treated twice daily with mouthrinses containing either tiodonium chloride, stannous fluoride or a placebo. Although the results for tiodonium chloride were unremarkable, stannous fluoride mouthrinses proved to be significantly effective in removing dental plaque and in restricting the ability of plaque to lower the pH of sugar solutions.
D000190:Actinomyces / Q000502:physiology; D000818:Animals; D003773:Dental Plaque / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control*; D004037:Diet, Cariogenic; D005260:Female; D005453:Fluorescence; D005459:Fluorides / Q000627:therapeutic use*; D006863:Hydrogen-Ion Concentration; D009067:Mouthwashes / Q000627:therapeutic use*; D009861:Onium Compounds / Q000627:therapeutic use; D051381:Rats; D013295:Streptococcus mutans / Q000502:physiology; D013876:Thiophenes / Q000627:therapeutic use*; D014002:Tin Fluorides / Q000627:therapeutic use*
D009067:Mouthwashes; D009861:Onium Compounds; D013876:Thiophenes; D014002:Tin Fluorides; C020944:tiodonium chloride; D005459:Fluorides