title: A surface antigen marker for human monocytes.
abstract: Antisera have been raised in rabbits aginst human peritoneal macrophages. After absorption with tonsil cells the sera reacted, by direct and indirect immunfluorescence, with phagocytic mononuclear cells from a variety of tissues and, in addition, stained a small population of nonphagocytic non-T, non-B mononuclear cells present in blood, spleen, and marrow but absent or very rare in tonsil and thymus. The antisera may define a human monocyte-macrophage cell surface differentiation antigen (HuMA) and can be used to deplete or enrich reactive cell population.
mesh_terms: D000818:Animals; D000937:Antigen-Antibody Reactions; D000941:Antigens; D001853:Bone Marrow / Q000276:immunology; D002462:Cell Membrane / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D006801:Humans; D007106:Immune Sera; D008214:Lymphocytes / Q000276:immunology; D051379:Mice / Q000276:immunology; D009000:Monocytes / Q000276:immunology*; D014066:Palatine Tonsil / Q000276:immunology; D010587:Phagocytosis; D011817:Rabbits / Q000276:immunology; D013045:Species Specificity; D013154:Spleen / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology
chemical_list: D000941:Antigens; D000939:Epitopes; D007106:Immune Sera