title: [Catecholamines and their metabolic enzymes in the hypothalamus of rats after a flight on the Kosmos-782 biosatellite].
abstract: The concentration of catecholamines, and activity of enzymes involved in their synthesis (tyrosine hydroxylase and dopamine-beta-hydroxylase) and degradation (monoamine oxidase) were measured in the hypothalamus of rats flown for 19.5 days aboard the biosatellite Cosmos-782, synchronous and vivarium controls sacrificed on R+O and R+25 days. No significant changes in the above parameters of the flight rats were found. The findings give evidence that a prolonged space flight induces no changes in the content, synthesis or degradation of catecholamines in the rat hypothalamus. This seems to indicate that weightlessness does not act as an acute stressor.
mesh_terms: D000818:Animals; D002395:Catecholamines / Q000378:metabolism*; D004299:Dopamine beta-Hydroxylase / Q000378:metabolism; D004789:Enzyme Activation; D004798:Enzymes / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism*; D008297:Male; D008995:Monoamine Oxidase / Q000378:metabolism; D051381:Rats; D013026:Space Flight; D013997:Time Factors; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism; D014586:USSR
chemical_list: D002395:Catecholamines; D004798:Enzymes; D014446:Tyrosine 3-Monooxygenase; D004299:Dopamine beta-Hydroxylase; D008995:Monoamine Oxidase
vernacular_title: Katekholaminy i fermenty ikh obmena v gipotalamuse krys posle poleta na biosputnike "Kosmos-782".