title: Antihistamine blockade of the ovarian hyperstimulation syndrome. II. Possible role of antigen-antibody complexes in the pathogenesis of the syndrome.
abstract: Antihistamine can prevent the ovarian hyperstimulation syndrome in the rabbit. The mechanism underlying this experimental observation has not been elucidated. Our experiments were directed at the question of whether antigen-antibody complexes are a factor in the development of the ovarian hyperstimulation syndrome. The results do not support the theory that antigen-antibody complexes play a role in the pathogenesis of this syndrome.
mesh_terms: D000818:Animals; D000906:Antibodies / Q000032:analysis; D000936:Antigen-Antibody Complex; D000937:Antigen-Antibody Reactions; D005260:Female; D006041:Goats / Q000276:immunology; D006634:Histamine H1 Antagonists / Q000494:pharmacology / Q000627:therapeutic use*; D006636:Histamine Release / Q000187:drug effects; D010049:Ovarian Diseases / Q000209:etiology / Q000276:immunology* / Q000517:prevention & control; D011234:Precipitins / Q000032:analysis; D051381:Rats; D013577:Syndrome
chemical_list: D000906:Antibodies; D000936:Antigen-Antibody Complex; D006634:Histamine H1 Antagonists; D011234:Precipitins