title: [Changes in cerebrospinal fluid pressure following administration of sodium hydroxybutyrate and viadril-G to patients with brain tumors].
abstract: The effect of sodium oxybutyrate and viadril-G on intracranial pressure was tested in 30 patients with tumours in injecting an anaesthetic. The electromanometric method was applied in measuring the pressure of cerebrospinal fluid and central venous pressure. A considerable reduction of intracranial pressure was noted in inducing anaesthesia by sodium oxybutyrate (by 34.5%) and viadril-G (by 24%), which was attended by an increase in perfusional brain pressure.
mesh_terms: D000293:Adolescent; D000328:Adult; D000771:Anesthesia, Intravenous; D001932:Brain Neoplasms / Q000134:cerebrospinal fluid / Q000601:surgery*; D002555:Cerebrospinal Fluid / Q000187:drug effects; D006801:Humans; D006885:Hydroxybutyrates / Q000008:administration & dosage*; D007427:Intracranial Pressure / Q000187:drug effects*; D008875:Middle Aged; D011277:Pregnanediones / Q000008:administration & dosage*; D012978:Sodium Oxybate / Q000008:administration & dosage*; D013874:Thiopental / Q000008:administration & dosage*
chemical_list: D006885:Hydroxybutyrates; D011277:Pregnanediones; D012978:Sodium Oxybate; D013874:Thiopental
vernacular_title: Izmeneniia davleniia spinnomozgovoĭ zhidkosti pod vliianiem oksibutirata natriia i viadrila-G u bol'nykh s opukholiami golovnogo mozga.