title: [Postoperative analgesia by constant flow injection of lignocaine in obstetrical and gynecologic surgery].
abstract: 154 surgical patients were given post-operative analgesia by peridural injection at a constant flow in the post-operative period after obstetric or gynecological surgery. These patients received 536.2 +/- 105.3 mu mol.h-1 (145.2 +/- 28.5 mg.h-1) of lignocaine for 46.97 +/- 15.56 h through a catheter omserted between L1-L2. The drug was given in concentrations which varied between: 27.7 to 18.5 m mol.l-1 (0.75 to 0.50 p. 100) depending on the age; and the volume varied between 17.5 to 30 ml.h-1 depending on the height. Satisfactory analgesia in 87 p. 100 of cases allowed all supplementary analgesia to be stopped. The only significant hemodynamic effect was a slight tachycardia (+ 15 p. 100). Two undesirable side effects were noted: a transitory but well-defined (type 2 or 3) motor paralysis, and an accumulation of plasma lignocaine (40 mu mol.l-1 (1.1 microgram.ml-1) at 48 h).
mesh_terms: D000698:Analgesia / Q000009:adverse effects / Q000379:methods*; D000767:Anesthesia, Epidural / Q000009:adverse effects / Q000379:methods*; D000771:Anesthesia, Intravenous; D002585:Cesarean Section; D005260:Female; D005831:Genital Diseases, Female / Q000601:surgery*; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage* / Q000009:adverse effects; D009458:Neuroleptanalgesia; D011182:Postoperative Care / Q000009:adverse effects / Q000379:methods*; D011247:Pregnancy
chemical_list: D008012:Lidocaine
vernacular_title: Analgésie post-opératoire par injection péridurale à débit constant en chirurgie obstétricale et gynécologique utilisant la lignocaïne.