Comparative trial of amoxycillin and chloramphenicol in treatment of typhoid fever in adults.
A randomised clinical trial in 124 adult patients with typhoid fever, proved by blood culture, showed that amoxycillin in a dosage of 1 g. six-hourly for fourteen days is an alternative to chloramphenicol, which has hitherto been regarded as the drug of choice.
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000658:Amoxicillin / Q000008:administration & dosage / Q000627:therapeutic use; D000667:Ampicillin / Q000031:analogs & derivatives*; D002353:Carrier State / Q000188:drug therapy; D002648:Child; D002701:Chloramphenicol / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012485:Salmonella typhi / Q000302:isolation & purification; D013997:Time Factors; D014435:Typhoid Fever / Q000188:drug therapy* / Q000382:microbiology / Q000401:mortality
D002701:Chloramphenicol; D000667:Ampicillin; D000658:Amoxicillin