Urinary lithogenesis in Sudanese patients: a study of stone formers.
This prospective study confirms the previously reported high incidence of uric acid lithiasis in the Sudan. Despite this fact urinary pH in patients in whom stones formed was not significantly different from controls (p greater than 0.05). However, a significantly high serum uric acid level (p less than 0.01) was associated with recurrent and/or bilateral stones. In patients with single episodes of stones significant hyponatremia (p less than 0.001) may indicate excessive sweating. The resulting low urine output supersaturated with crystals may explain lithogenesis in this group of patients.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002118:Calcium / Q000097:blood / Q000652:urine; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012964:Sodium / Q000097:blood; D013397:Sudan; D014527:Uric Acid / Q000032:analysis / Q000097:blood / Q000652:urine; D014545:Urinary Calculi / Q000209:etiology* / Q000378:metabolism
D014527:Uric Acid; D012964:Sodium; D002118:Calcium