Fetal effects of regular salicylate ingestion in pregnancy.
The babies of 144 mothers who took salicylates regularly in pregnancy are described. These babies had a significantly reduced birth-weight compared with controls; many of them had a raised cord-blood salicylate level but had no clinical evidence of bleeding or hypoglycaemia. Their perinatal mortality was increased, but the incidence of congenital anomalies was not significantly raised.
D000015:Abnormalities, Multiple / Q000139:chemically induced; D001724:Birth Weight / Q000187:drug effects*; D005260:Female; D005313:Fetal Death / Q000139:chemically induced; D005333:Fetus / Q000187:drug effects*; D005865:Gestational Age; D006228:Hand Deformities, Congenital; D006330:Heart Defects, Congenital / Q000139:chemically induced; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D007416:Intestinal Perforation / Q000151:congenital; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D012459:Salicylates / Q000009:adverse effects* / Q000097:blood
D012459:Salicylates