alpha-Fetoprotein detected in rat transplantable hepatomas by radioimmunoassay.
Production of rat alpha-fetoprotein by transplantable ascites hepatoma was studied by radioimmunoassay method. alpha-Fetoprotein was detected in sera from rats bearing 22 out of 50 ascites hepatoma cell lines that were previously negative for the presence of alpha-fetoprotein by the Ouchterlony test. alpha-Fetoprotein was also detected with high prevalency in Morris hepatomas and sublines of Yoshida sarcoma by this assay system.
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000032:analysis*; D002460:Cell Line; D005326:Fetal Proteins / Q000032:analysis*; D006041:Goats / Q000276:immunology; D005779:Immunodiffusion; D008113:Liver Neoplasms / Q000032:analysis*; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental; D011817:Rabbits / Q000276:immunology; D011863:Radioimmunoassay / Q000379:methods*; D051381:Rats; D012517:Sarcoma, Yoshida / Q000032:analysis; D000509:alpha-Fetoproteins / Q000032:analysis* / Q000276:immunology
D005326:Fetal Proteins; D000509:alpha-Fetoproteins