In vitro binding of metabolically activated [14C]-ledakrin, or 1-nitro-9-14C-(3'-dimethylamino-N-propylamino) acridine, a new antitumor and DNA cross-linking agent, to macromolecules of subcellular fractions isolated from rat liver and HeLa cells.
D000166:Acridines / Q000378:metabolism*; D000818:Animals; D003600:Cytosol / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D006898:Hydroxylamines / Q000378:metabolism; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism* / Q000648:ultrastructure; D046911:Macromolecular Substances; D008297:Male; D009249:NADP / Q000378:metabolism; D009564:Nitracrine / Q000378:metabolism*; D051381:Rats; D013347:Subcellular Fractions / Q000378:metabolism*
D000166:Acridines; D006898:Hydroxylamines; D046911:Macromolecular Substances; D009249:NADP; D009564:Nitracrine