title: [Determination of chemoantibiotic levels in tissues and biological fluids (author's transl)].
abstract: On the premise that a microorganism is sensitive or resistant to a chemoantibiotic according to it's concentrations in biological fluids and tissues, the A. examines those methods available in chemoantibiotic titration such as chemical, enzymatic, radio-immunologic, turbidimetric, potentiometric and agar-diffusion methods. By further evaluating the limits and capacities of these different methods, the A. describes in larger detail the agar-diffusion method which is considered more sensitive, practical and efficient. A brief report is made on the possibility of measuring antibiotic association.
mesh_terms: D000362:Agar; D000890:Anti-Infective Agents / Q000032:analysis*; D004058:Diffusion; D006863:Hydrogen-Ion Concentration; D008722:Methods; D009391:Nephelometry and Turbidimetry; D011199:Potentiometry; D011863:Radioimmunoassay; D014018:Tissue Distribution
chemical_list: D000890:Anti-Infective Agents; D000362:Agar
vernacular_title: Determinazione dei livelli di chemioantibiotici in liquidi biologici e nei tessuti.