Methemoglobinemia: nitrobenzene ingestion.
In an unusually severe case of multiple toxin ingestion, a 48-year-old man ingested approximately 300 cc of Hoppe's Gunpower Solvent #9, which contains kerosene, denatured ethyl alcohol, oil and nitrobenzene. The major manifestation was nitrobenzene-induced methemoglobinemia of rapid onset. Treatment involves the judicious use of 1% methylene blue plus, in severe cases, hemodynamic and ventilatory support. The patient recovered after 48 hours and was transferred to the psychiatric service with continued follow-up for a mild poison-induced hemolytic anemia.
D000743:Anemia, Hemolytic / Q000139:chemically induced; D003131:Combined Modality Therapy; D004338:Drug Combinations; D004630:Emergencies; D006801:Humans; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D008875:Middle Aged; D009578:Nitrobenzenes / Q000506:poisoning*; D011041:Poisoning / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D012997:Solvents / Q000506:poisoning*
D004338:Drug Combinations; D009578:Nitrobenzenes; D012997:Solvents