Aluminum-magnesium antacids and the bioavailability of ketoscilium in man.
The bioavailability of the gastric secretory inhibitor 3-hydroxy-8-(p-phenylphenacyl)-1 alphaH, 5 alphaH-tropanium bromide (-)-tropate (ketoscilium, Ulcesium) is not affected by a single dose of an aluminum-magnesium antacid although binding occurs in vitro.
D000328:Adult; D000535:Aluminum / Q000494:pharmacology*; D000863:Antacids / Q000494:pharmacology*; D001286:Atropine Derivatives / Q000378:metabolism*; D001682:Biological Availability; D005243:Feces / Q000032:analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007408:Intestinal Absorption / Q000187:drug effects; D008274:Magnesium / Q000494:pharmacology*; D008297:Male
D000863:Antacids; D001286:Atropine Derivatives; D000535:Aluminum; D008274:Magnesium