The expression of human beta2-microglobulin on human spermatozoa.
The expression of human beta2-microglobulin was detected on human spermatozoa from 7 donors using a cytotoxicity assay and indirect immunofluorescence. Inhibition experiments using purified beta2-microglobulin demonstrated the specificities of these reactions. We were able to localize beta2-microglobulin on human spermatozoa on the post-acrosomal region at a similar location to those described for HL-A antigen and for early embryonic antigen +t12, but also at the end of the intermediary piece and the beginning of the tail.
D000937:Antigen-Antibody Reactions; D001609:Beta-Globulins / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D013094:Spermatozoa / Q000032:analysis* / Q000648:ultrastructure; D001613:beta 2-Microglobulin / Q000032:analysis* / Q000276:immunology
D001609:Beta-Globulins; D001613:beta 2-Microglobulin