Simultaneous investigation and treatment of suspected acute adrenal insufficiency.
The increase in plasma-fluorogenic-corticosteroids in response to a single injection of tetracosactrin depot was measured in eleven patients with suspected acute renal insufficiency who were treated simultaneously with prednisolone and deoxycorticosterone acetate (D.O.C.A.). Acute adrenal insufficiency was excluded in seven patients within 24 hours. There was no response in the remaining four patients, and prolonged corticotrophin stimulation tests confirmed the diagnosis of Addison's disease.
D015062:11-Hydroxycorticosteroids / Q000097:blood; D000208:Acute Disease; D000224:Addison Disease / Q000175:diagnosis / Q000188:drug therapy; D000328:Adult; D000368:Aged; D003366:Cosyntropin; D003900:Desoxycorticosterone; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000031:analogs & derivatives / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D013268:Stimulation, Chemical
D015062:11-Hydroxycorticosteroids; D003366:Cosyntropin; D003900:Desoxycorticosterone; D011239:Prednisolone; D006854:Hydrocortisone