title: Tyrosine hydroxylase immunoreactivity in familial dysautonomia.
abstract: Tyrosine hydroxylase antigen was localized immunohistochemically in sympathetic neurons from human autopsy tissue. The reaction persists in paraffin-embedded tissue, and the method is applicable to archival specimens. Increased amounts in this antigen per cell may partially compensate for decreased numbers of sympathetic neurons in familial dysautonomia.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004402:Dysautonomia, Familial / Q000201:enzymology* / Q000473:pathology; D005725:Ganglia, Autonomic / Q000201:enzymology / Q000473:pathology; D006801:Humans; D007223:Infant; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism
chemical_list: D014446:Tyrosine 3-Monooxygenase