title: [Lupos erythematosus discovered during the course of a toxicodermia (author's transl)].
abstract: The authors describes four cases of lupus erythematosus (LE) diagnosed during the course of a medication toxicodermia, which was always acute and variable in its severity (in one case it concerned a Lyell's syndrome). The lupus affection was made evident by the toxicodermia and lupic manifestations may regress spontaneously after recovery from the skin disorder. This emphasizes the value of clinical and biological testing for the presence of LE in severe cases of toxicodermia in women, more particularly immunofluorescent studies of the basal structures in the cutaneous lesions.
mesh_terms: D000328:Adult; D000368:Aged; D000667:Ampicillin / Q000009:adverse effects; D001073:Aprindine / Q000009:adverse effects; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis*; D009113:Muramidase / Q000009:adverse effects; D011342:Procainamide / Q000009:adverse effects; D012460:Sulfasalazine / Q000009:adverse effects; D013839:Thiamphenicol / Q000009:adverse effects
chemical_list: D012460:Sulfasalazine; D001073:Aprindine; D000667:Ampicillin; D009113:Muramidase; D013839:Thiamphenicol; D011342:Procainamide
vernacular_title: Lupus érythémateux disséminés révélés par une toxidermie.