title: [The effects on caries in animal experiments when reducing sugar in cola-drinks(author's transl)].
abstract: The effect of stepwise sugar reduction in cola drinks was tested in a programmed animal experiment using Wistar rats. In a parallel study the pH-decrease at different sucrose concentrations was measured in vitro using a plaque model system which involved s. mutans (strain OMZ 176). The reduction of sugar contents by 20%, 33% und 42% results in a lower acid production by s. mutans strain connected with a decrease of the experimental produced caries. For this reason the sugar restriction in cola drinks will be seen as a contribution towards an improvement of dental health.
mesh_terms: D000818:Animals; D001628:Beverages / Q000009:adverse effects*; D050260:Carbohydrate Metabolism; D002241:Carbohydrates / Q000008:administration & dosage*; D003470:Culture Media; D003731:Dental Caries / Q000209:etiology / Q000517:prevention & control*; D003773:Dental Plaque / Q000517:prevention & control; D004037:Diet, Cariogenic; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D051381:Rats; D013295:Streptococcus mutans / Q000378:metabolism; D013997:Time Factors
chemical_list: D002241:Carbohydrates; D003470:Culture Media
vernacular_title: Auswirkung der Zuckerreduzierung im Cola-Getränk auf die Karies im programmierten Rattenexperiment.