Superoxide and hydrogen peroxide production and NADPH oxidation stimulated by nitrofurantoin in lung microsomes: possible implications for toxicity.
D000323:Adrenochrome / Q000378:metabolism; D000818:Animals; D006861:Hydrogen Peroxide / Q000378:metabolism*; D066298:In Vitro Techniques; D008168:Lung / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008861:Microsomes / Q000187:drug effects / Q000378:metabolism*; D009249:NADP / Q000378:metabolism*; D009582:Nitrofurantoin / Q000494:pharmacology* / Q000633:toxicity; D010084:Oxidation-Reduction; D010100:Oxygen / Q000378:metabolism*; D051381:Rats; D013268:Stimulation, Chemical; D013482:Superoxide Dismutase / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism*
D013481:Superoxides; D009249:NADP; D000323:Adrenochrome; D009582:Nitrofurantoin; D006861:Hydrogen Peroxide; D013482:Superoxide Dismutase; D010100:Oxygen