title: Long-term culture of guinea pig tongue cells: a suitable interferon system.
abstract: The interferon system was investigated in a long-term culture of guinea pig tongue (GPT) cells. Interferon synthesis was induced with Newcastle disease virus (B strain) and f2 phage double-stranded RNA. Guinea pig interferons were about 2 times more active in cell cultures established from guinea pig embryos than in the GPT cells. Human leukocyte and mouse peritoneal cell interferons were active in this cell system also.
mesh_terms: D000818:Animals; D003090:Coliphages; D046508:Culture Techniques; D006168:Guinea Pigs; D006801:Humans; D007372:Interferons / Q000096:biosynthesis* / Q000494:pharmacology; D007739:L Cells; D007962:Leukocytes; D009522:Newcastle disease virus; D012367:RNA, Viral / Q000494:pharmacology; D014059:Tongue
chemical_list: D012367:RNA, Viral; D007372:Interferons