title: Thyroxine utilization rate in sucking pigs.
abstract: In 10 suckling pigs age 28--34 days, thyroxine utilization rate (TUR) was determined by means of the isotope dilution procedure. For this purpose biological half-life of T4 was estimated during 96 h of blood sampling and serum T4 concentration was measured directly by a competitive protein-binding technique. High rate of the peripheral hormonal-iodine metabolism (from 10.3 +/- 0.6 to 21.2 +/- 1.2 mug T4/kg/day) was found in the one-month old pigs. TUR value calculated for these pigs corresponds to that reported in human infants and it is much higher than in the growing ruminants.
mesh_terms: D000284:Administration, Oral; D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D006207:Half-Life; D007275:Injections, Intravenous; D007454:Iodides / Q000008:administration & dosage; D007457:Iodine Radioisotopes; D012964:Sodium / Q000008:administration & dosage; D013552:Swine / Q000378:metabolism*; D013960:Thyroid Function Tests / Q000379:methods; D013974:Thyroxine / Q000008:administration & dosage; D013997:Time Factors
chemical_list: D007454:Iodides; D007457:Iodine Radioisotopes; D012964:Sodium; D013974:Thyroxine