title: Antivenom in sea-snake bit poisoning.
abstract: Among a series of 101 patients bitten by sea-snakes in Malaya in the years 1957-64, 80% were fishermen. Bathers and divers are occasionally bitten. Before sea-snake antivenom became available the mortality-rate (despite the high toxicity of sea-snake venom) was only 10%; however, of 11 with serious poisoning, 6 died. Subsequently 10 patients with serious poisoning received specific sea-snake antivenom; 2 patients, admitted moribund, temporarily improved but died, and 8 patients recovered dramatically. In serious poisoning the suitable dosage of intravenous sea-snake antivenom is 3000-10,000 units; in mild poisoning 1000-2000 units should suffice.
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000997:Antivenins / Q000008:administration & dosage / Q000627:therapeutic use*; D001219:Aspartate Aminotransferases / Q000097:blood; D002648:Child; D006801:Humans; D008296:Malaysia; D008297:Male; D011188:Potassium / Q000097:blood; D012909:Snake Bites / Q000188:drug therapy / Q000201:enzymology / Q000401:mortality; D013997:Time Factors
chemical_list: D000997:Antivenins; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D011188:Potassium