Influence of preincubation of primary dog kidney cell cultures on the multiplication of attenuated mumps virus.
An attenuated mumps virus strain multiplied in primary dog kidney cells to significantly higher titres in cultures preincubated for 1-5 weeks at 20-25 degrees C before inoculation as compared with cultures infected immediately after their growth became confluent. The nature of this phenomenon is discussed.
D000818:Animals; D002460:Cell Line; D004285:Dogs; D007668:Kidney; D009109:Mumps virus / Q000254:growth & development* / Q000472:pathogenicity; D013696:Temperature; D014774:Virulence; D014776:Virus Cultivation / Q000379:methods*; D014779:Virus Replication