title: The effect of multiple psychotropic drugs on the accommodation of pre-presbyopes.
abstract: Among 1,000 psychiatric patients in a Veterans Administration hospital, there were 15 in the age group 21--41 years who complained of difficulty at near and who showed reduced accommodation. All 15 were receiving benztropine mesylate (Cogentin) and most also received a phenothiazine or a butyrophenone. The reduction in accommodation ranged from 40 to 100%. Data are insufficient to correlate doses of specific drugs with the precise extent of the impairment of accommodation.
mesh_terms: D000065:Accommodation, Ocular / Q000187:drug effects*; D000328:Adult; D000367:Age Factors; D014150:Antipsychotic Agents / Q000009:adverse effects; D001590:Benztropine / Q000009:adverse effects; D004359:Drug Therapy, Combination; D005260:Female; D006220:Haloperidol / Q000009:adverse effects; D006801:Humans; D008297:Male; D010640:Phenothiazines; D011619:Psychotropic Drugs / Q000009:adverse effects*; D014792:Visual Acuity / Q000187:drug effects
chemical_list: D014150:Antipsychotic Agents; D010640:Phenothiazines; D011619:Psychotropic Drugs; D001590:Benztropine; D006220:Haloperidol