title: [A study of gamma-glutamyl-transpeptidase and of the ratio of IgA to transferrin in the pregnant woman (and when using oral contraception) and in the newborn (author's transl)].
abstract: The authors confirm the absence of a marked variation in levels of gamma-glutamyl-transpeptidase in women under the influence of oestrogens, but a considerable rise in this enzyme in the newborn, particularly after delivery following vaginal obstetrical manoeuvre. They base these findings on 242 samples taken from pregnant women in the 3 trimesters of normal pregnancies and after delivery, and in the cord blood of newborn infants as well as in patients taking oral contraception. There is a slight rise in the levels of immunoglobulins A in the 3rd trimester of pregnancy. The overall rise in the blood levels of transferrin under the effect of oestrogens is confirmed. Norms were obtained for the levels of the IgA/T ratio which drops progressively as pregnancy progresses and with oral contraception. It has been found that in the last two trimesters the upper limit of the normal is 1 for the IgA/T ratio as compared with 1.9 in the general population. The study of these constants is of value when screening for maternal alcoholism and as a consequence for the prevention of the fetal alcohol syndrome.
mesh_terms: D003276:Contraceptives, Oral; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007231:Infant, Newborn; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D014168:Transferrin / Q000032:analysis*; D005723:gamma-Glutamyltransferase / Q000032:analysis*
chemical_list: D003276:Contraceptives, Oral; D007070:Immunoglobulin A; D014168:Transferrin; D005723:gamma-Glutamyltransferase
vernacular_title: Etude de la gamma-glutamyl-transpeptidase et du rapport IgA sur transferrine chez la femme enceinte (et sous contraception orale) et le nouveau-né.