Thyroidal accumulation of 131I during adrenal gland scintigraphy with 131I-19-iodocholesterol: effects of thyroid blocking agents.
131I-19-iodocholesterol has been used by Beierwaltes et al., to visualize human adrenal glands. The tissue distribution of 131I-19-iodocholesterol was determined by Morita et al., both in dogs and men. No data have been reported on thyroidal 131I accumulation after administration of the radiopharmaceutical. We calculated the percentage uptake of radioactivity in the human thyroid gland inhibited with various therapeutic agents (triiodothyronine (T3), Lugol's solution, potassium perchlorate (KC1O4).
D000307:Adrenal Gland Diseases / Q000000981:diagnostic imaging / Q000378:metabolism; D000311:Adrenal Glands / Q000000981:diagnostic imaging*; D013956:Antithyroid Agents / Q000494:pharmacology*; D002784:Cholesterol / Q000031:analogs & derivatives / Q000378:metabolism*; D006801:Humans; D007455:Iodine / Q000378:metabolism*; D007457:Iodine Radioisotopes; D010472:Perchlorates / Q000494:pharmacology; D011859:Radiography; D013961:Thyroid Gland / Q000187:drug effects / Q000378:metabolism*; D013997:Time Factors; D014284:Triiodothyronine / Q000494:pharmacology*
D013956:Antithyroid Agents; D007457:Iodine Radioisotopes; D010472:Perchlorates; D014284:Triiodothyronine; D007455:Iodine; D002784:Cholesterol