HL-A27 and anterior uveitis.
HL-A types were determined in 90 successive patients with non-granulomatous uveitis. Fifty-one were HL-A27 positive (55.7%) compared to 8.2% of controls. Of 16 patients with ankylosing spondylitis, 13 were HL-A27 positive, as were two patients with a history of Reiter's syndrome. Twenty-eight patients were HL-A27 positive but had no evidence of rheumatic disease. The findings are discussed in relation to the possible pathogenesis of uveitis.
D000208:Acute Disease; D016918:Arthritis, Reactive / Q000150:complications / Q000276:immunology; D000939:Epitopes; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006650:Histocompatibility Testing; D006801:Humans; D010641:Phenotype; D011565:Psoriasis / Q000150:complications / Q000276:immunology; D013167:Spondylitis, Ankylosing / Q000150:complications / Q000276:immunology; D014605:Uveitis / Q000150:complications / Q000276:immunology*
D000939:Epitopes; D006680:HLA Antigens; D006649:Histocompatibility Antigens