title: Biochemical findings in multiple sclerosis. II. A detailed study of the serum IgA, IgG and IgM levels of 772 MS patients compared with 226 neurological controls.
abstract: In the second paper of this series, a detailed study of the three main serum immunoglobulins for a group of 772 MS patients is compared with a group of 226 neurological controls. The results are studied according to sex and different age groups. Except for a slight elevation of the IGM levels in the MS group, especially between 40 and 60 years, no clear cut distinction between the two groups of patients was found.
mesh_terms: D000328:Adult; D000367:Age Factors; D001798:Blood Proteins / Q000032:analysis; D002493:Central Nervous System Diseases / Q000276:immunology; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D006242:Haptoglobins / Q000032:analysis; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy / Q000276:immunology*; D012737:Sex Factors
chemical_list: D001798:Blood Proteins; D006242:Haptoglobins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D003520:Cyclophosphamide