Development of gamma-glutamylcysteine synthetase and oxoprolinase in rat kidney.
gamma-Glutamylcysteine synthetase is present in barely detectable amounts in foetal kidney. Its activity starts to increase in postnatal life. In contrast, oxoproline is already found in significant quantities in the foetal tissue. Both enzymes show marked elevation in activities during the weaning period.
D000375:Aging; D000581:Amidohydrolases / Q000378:metabolism*; D000818:Animals; D005260:Female; D005333:Fetus; D005721:Glutamate-Cysteine Ligase / Q000378:metabolism*; D007668:Kidney / Q000201:enzymology* / Q000254:growth & development; D008297:Male; D010453:Peptide Synthases / Q000378:metabolism*; D011752:Pyroglutamate Hydrolase / Q000378:metabolism*; D051381:Rats
D000581:Amidohydrolases; D011752:Pyroglutamate Hydrolase; D010453:Peptide Synthases; D005721:Glutamate-Cysteine Ligase