An immunological factor in epilepsy.
It is proposed that epileptic discharges could be the result of an autoimmune response to either an antigen released during tissue destruction or an infective agent. A possible mechanism involves the blocking by antibodies of transmitter receptor sites at synapses, whereby synaptic transmission is reduced.
D000818:Animals; D000906:Antibodies; D000917:Antibody Formation; D000918:Antibody Specificity; D000936:Antigen-Antibody Complex; D000941:Antigens; D001327:Autoimmune Diseases; D001921:Brain / Q000276:immunology; D004827:Epilepsy / Q000097:blood / Q000276:immunology* / Q000503:physiopathology; D000882:Haplorhini; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D009157:Myasthenia Gravis / Q000097:blood; D051381:Rats; D009435:Synaptic Transmission
D000906:Antibodies; D000936:Antigen-Antibody Complex; D000941:Antigens; D007070:Immunoglobulin A