title: [Surgical aspects of the acid-producing function of the stomach in peptic ulcer].
abstract: In the paper, the results of studies on the acid-producing function of the stomach in ulcerous disease and its dependence on regulatory disturbances (neuro-humoral) and the type of an irritant are analysed. It was found that patients with ulcerous disease were characterized by dysfunction of the vegetative nervous system, and as a result of it there is a pathological irritability of acid-producing cells being one of causes of fluctuations in acidity at all stages of gastric secretion. It is concluded that gastric secretion may not be used in pathogenetic foundation of surgical methods of treatment for ulcerous disease, and for this purpose one should act in accordance with the state of neuro-humoral mechanisms of regulation of the gastric function concerned.
mesh_terms: D004381:Duodenal Ulcer / Q000503:physiopathology / Q000601:surgery; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism*; D006636:Histamine Release; D006801:Humans; D010437:Peptic Ulcer / Q000503:physiopathology*; D012018:Reflex; D013270:Stomach / Q000294:innervation; D013276:Stomach Ulcer / Q000503:physiopathology / Q000601:surgery; D013564:Sympathetic Nervous System / Q000503:physiopathology
vernacular_title: Khirurgicheskie aspekty kislotoprodutsiruiushcheĭ funktsii zheludka pri iazvennoĭ bolezni