title: Miconazole in the treatment of candidiasis of the digestive tract.
abstract: Miconazole nitrate tablets were used in the treatment of candidiasis of the oral cavity and the digestive tract. In 5 out of 6 patients with severe, predisposing factors and who had received previous unsuccessful antimycotic therapy, clinical improvement occurred after a few days of miconazole treatment. Mycological cure of these 5 patients was achieved after 1-11 weeks of treatment. Three of the 5 cured patients relapsed after 3 months, due to basic failure. One patient complained of the drug's unpleasant taste. Otherwise, no side effects were observed. There was no apparent development of any resistance to the drug.
mesh_terms: D000328:Adult; D002177:Candidiasis / Q000188:drug therapy*; D002180:Candidiasis, Oral / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D004935:Esophageal Diseases / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D007410:Intestinal Diseases / Q000188:drug therapy*; D007413:Intestinal Mucosa / Q000382:microbiology; D008297:Male; D008825:Miconazole / Q000627:therapeutic use*; D008875:Middle Aged; D010608:Pharyngeal Diseases / Q000188:drug therapy*
chemical_list: D007093:Imidazoles; D008825:Miconazole