[pH changes and the K+ and Na+ concentration in the blood of the coronary vein in experimental myocardial infarct complicated and not complicated by ventricular fibrillation].
It was found that following occlusion of the coronary artery in dogs, the rate of increase in K+ concentration in blood plasma draining directly from the focus of ischemia is greater in cases complicated by ventricular fibrillation. Fibrillation always occurs against the background of a decrease in pH and an increase in the K+ level in blood plasma draining from the focus of ischemia. It is suggested that inhibition of the development of disorders of acid-base and ion equilibrium in the myocardium would be an effective means of preventing ventricular fibrillation in the acute stage of myocardial infarction.
D000137:Acid-Base Imbalance / Q000097:blood*; D000818:Animals; D002414:Cations, Monovalent; D003331:Coronary Vessels / Q000378:metabolism*; D004285:Dogs; D005260:Female; D006863:Hydrogen-Ion Concentration; D008297:Male; D009203:Myocardial Infarction / Q000097:blood* / Q000150:complications; D011188:Potassium / Q000097:blood*; D012964:Sodium / Q000097:blood*; D014693:Ventricular Fibrillation / Q000097:blood*
D002414:Cations, Monovalent; D012964:Sodium; D011188:Potassium
Ob izmeneniiakh pH i kontsentratsii K+ i Na+ v krovi koronarnoĭ veny pri éksperimental'nom infarkte miokarda, oslozhennom i ne oslozhnennom fibrilliatsieĭ zheludochkov.