title: Complement - fixation in the interaction of normal rabbit gamma G' globulin and its Fab' fragment.
abstract: Complement consumption induced by Fab' fragments of rabbit IgG, irrespectively of their state of aggregation, requires the presence of homologous rabbit IgG. Up to a certain concentration of Fab' fragment, the amount of complement fixed is a linear function of the Fab' fragment dose, but further raising of the Fab'-fragment concentration does not result in complete complement consumption in the sample. The interaction between Fab' fragment and IgG is not strictly species specific.
mesh_terms: D000818:Animals; D003168:Complement Fixation Tests; D006168:Guinea Pigs; D007140:Immunoglobulin Fab Fragments; D011817:Rabbits; D013045:Species Specificity; D005719:gamma-Globulins / Q000378:metabolism*
chemical_list: D007140:Immunoglobulin Fab Fragments; D005719:gamma-Globulins