title: Abnormal leucocyte composition and sodium transport in essential hypertension.
abstract: Cation transport and electrolyte composition were studied in leucocytes from 17 patients with uncomplicated essential hypertension. Significant increases in cell sodium and water contents, associated with a depression of the rate-constant for active sodium efflux, were found in the hypertensive patients. These abnormalities in cell sodium transport may possibly be related to mechanisms of hypertension.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000418:Albumins; D001693:Biological Transport, Active; D001834:Body Water / Q000032:analysis / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000097:blood*; D007457:Iodine Radioisotopes; D007962:Leukocytes / Q000032:analysis / Q000378:metabolism*; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D011188:Potassium / Q000032:analysis / Q000097:blood / Q000378:metabolism; D011851:Radioactivity; D012964:Sodium / Q000032:analysis / Q000097:blood / Q000378:metabolism*
chemical_list: D000418:Albumins; D007457:Iodine Radioisotopes; D012964:Sodium; D011188:Potassium