title: [Psychological problems of incurable patients in old age (author's transl)].
abstract: Biological functions are regulated by feedback mechanisms. In old age disorders occur in this regulation by insufficiency of biochemical transmitters. The synthesizing enzymes of Tyrosine Hydroxylase, Tryptophan Hydroxylase, Dopa Decarboxylase and 5-Hydroxytryptophan Decarboxylase are diminished in old age. Minus symptoms as depression, or exhaustion and disorders of circulation occur. A substitution by biogenic transmitters is not possible, because these don't pass the blood-brain-barriere. Therefore a medication of psychopharmacological drugs is necessary. For instance Anxiety--tranquilizer, exhaustion--anti depressive drugs.
mesh_terms: D000368:Aged / Q000523:psychology*; D000375:Aging; D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D002262:Carboxy-Lyases / Q000378:metabolism; D002908:Chronic Disease / Q000523:psychology*; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*; D009420:Nervous System / Q000201:enzymology; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D014149:Tranquilizing Agents / Q000627:therapeutic use; D014365:Tryptophan Hydroxylase / Q000378:metabolism
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D011619:Psychotropic Drugs; D014149:Tranquilizing Agents; D014365:Tryptophan Hydroxylase; D002262:Carboxy-Lyases
vernacular_title: Seelische Probleme der unheilbaren Kranken im Alter.