title: Lack of effect of neurotransmitters on cyclic AMP phosphodiesterase activity in an insect CNS.
abstract: The inhibition of cyclic nucleotide phosphodiesterase from the nerve cord of Manduca sexta was studied using theophylline as a model compound. 11 putative neurotransmitters had no effect on enzyme activity.
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000378:metabolism*; D000818:Animals; D007700:Kinetics; D007915:Lepidoptera / Q000201:enzymology*; D009420:Nervous System / Q000201:enzymology*; D018377:Neurotransmitter Agents / Q000494:pharmacology*; D013806:Theophylline / Q000494:pharmacology
chemical_list: D018377:Neurotransmitter Agents; D013806:Theophylline; D015105:3',5'-Cyclic-AMP Phosphodiesterases