A double-blind study of melperone and placebo in hospitalized chronic alcoholics in postintoxication phase.
In a double-blind study in chronic alcoholics melperone (Buronil) was shown to significantly improve muscular and nervous tension, emotional lability, somatization, ability to sleep, anxiety, depression, paranoid ideation and presumed ability to work, but had no effect on alcoholic craving. The results received from three rating scales, and the theoretical aspects of alcoholism are discussed.
D000328:Adult; D000437:Alcoholism / Q000188:drug therapy* / Q000523:psychology; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002090:Butyrophenones / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D008875:Middle Aged; D010880:Piperidines / Q000627:therapeutic use; D010919:Placebos; D011569:Psychiatric Status Rating Scales; D011795:Surveys and Questionnaires
D014150:Antipsychotic Agents; D002090:Butyrophenones; D010880:Piperidines; D010919:Placebos; C008522:metylperon