Cell-mediated immunity in patients with renal adenocarcinoma.
The lymphocytotoxicity test was used to study the existence of immunologically active lymphocyte reactions in patients with renal carcinoma at different stages. In 9 patients with an advanced renal carcioma (stage IV) a low lymphocytotoxicity was found, while the examination of 7 patients with stage I and II renal tumours showed a high value of the lymphocytotoxicity test. The clinical importance of the lymphocytotoxicity test is discussed with special interest in a possible immunotherapy.
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000276:immunology* / Q000473:pathology; D000328:Adult; D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000276:immunology* / Q000473:pathology; D008213:Lymphocyte Activation; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009392:Nephrectomy; D011859:Radiography; D012077:Renal Artery / Q000000981:diagnostic imaging; D013601:T-Lymphocytes / Q000276:immunology
D000951:Antigens, Neoplasm; D000939:Epitopes