[Distribution of HB s Ag subtypes in a sample of acute viral hepatitis of type B in Northern Italy].
82 HBsAg from acute hepatitis B patients living in Northern Italy were subtyped. HBsAg has been detected by immunodiffusion (ID), electrosyneresis (ES), complement fixation (CF) and radioimmunoassay (RIA, Kit Ausria I and II, Abbott). Subtyping was performed by ES in 50 and by ID in 30 of the 82 assayed sera. An higher frequency of ayw subtype (83,1%) in comparison with adw subtype (16,9%) has been observed. No difference was found between adw and ayw subtypes analyzed as far as geographic-ethnic characters, incubation time, course and prognosis of the disease or the biohumoral indices. No patient was found to have both y and d specificities and so r determinant was never found.
D000208:Acute Disease; D000917:Antibody Formation; D000956:Antigens, Viral / Q000032:analysis; D003168:Complement Fixation Tests; D003378:Counterimmunoelectrophoresis; D000939:Epitopes; D006509:Hepatitis B / Q000382:microbiology*; D006511:Hepatitis B Antigens / Q000302:isolation & purification*; D006801:Humans; D005779:Immunodiffusion; D007558:Italy; D011233:Precipitin Tests; D011863:Radioimmunoassay
D000956:Antigens, Viral; D000939:Epitopes; D006511:Hepatitis B Antigens
Distribuzione di sottotipi di HBsAg in un campione di epatiti virali acute di tipo B del Nord Italia