Effect of iron on surface charge and hydrophobicity of Neisseria gonorrhoeae.
The effect of iron concentration during growth on the physicochemical surface properties of the colonial variants of Neisseria gonorrhoeae has been assessed by aqueous two-phase partitioning in a dextran-polyethyleneglycol system containing positively charged trimethylamino-polyethyleneglycol or hydrophobic polyethyleneglycol-palmitate. The complex effects of iron, in combination with other variables known to affect surface charge and hydrophobicity, have provided some clues as to the properties of the gonococcal surface that are important in promoting virulence.
D001426:Bacterial Proteins / Q000032:analysis; D003470:Culture Media; D010861:Fimbriae, Bacterial / Q000648:ultrastructure; D014644:Genetic Variation; D006863:Hydrogen-Ion Concentration; D007501:Iron / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects; D008565:Membrane Proteins / Q000032:analysis; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000502:physiology / Q000648:ultrastructure
D001426:Bacterial Proteins; D003470:Culture Media; D008565:Membrane Proteins; D007501:Iron