title: Effect of synthetic prostaglandin PGF2 alpha on the volume, acidity, and proteolytic activity of the abomasum juice in sheep.
abstract: Effect of synthetic prostaglandin PGF2 alpha on the volume acidity, and proteolytic activity of the abomasum juice in sheep. Act Physiol. Pol., 1979, 30 (2): 299--304. The investigations were carried out in 3 male sheep on the effect of Estrumate (a synthetic analogue of PGF2 alpha) on the secretion and composition of juice from the "small" abomasum. After intramuscular injection of optimum doses of the preparation (3.0--4.0 micrograms/kg of body weight) it was observed that the volume of the juice, its free HCl content, the total acidity the specific activity (expressed in Anson milliunits/ml) and the total activity (specific activity X volume of juice secreted in a given sample) increased significantly (p less than 0.01). Thus, the synthetic prostaglandin PGF2 alpha stimulates the secretory activity of abomasum glands in sheep.
mesh_terms: D000018:Abomasum / Q000187:drug effects* / Q000378:metabolism; D000818:Animals; D005260:Female; D005745:Gastric Acidity Determination; D006863:Hydrogen-Ion Concentration; D011460:Prostaglandins F / Q000494:pharmacology*; D012636:Secretory Rate / Q000187:drug effects
chemical_list: D011460:Prostaglandins F