title: Quinacrine-binding nerves: presence in the mouse ano-coccygeus muscle, disappearance after muscle transsection.
abstract: The anococcygeus muscle exhibits non-cholinergic, non-adrenergic, inhibitory neurotransmission. In the present paper we describe the presence of quinacrine-binding beaded nerve fibres in the mouse anococcygeus muscle. A large number of fibres were running parallel to the smooth muscle bundles. A second distribution of fibres formed an irregular plexus. No quinacrine-binding nerve cell bodies were found within the muscle. When the anococcygeus muscle was cut close to its insertion in the rectum, the proximal part lost most of its quinacrine-binding nerves 2-7 days after transsection. The results demonstrate a correlation between presumed non-cholinergic non-adrenergic neurotransmission and quinacrine-binding nervous elements.
mesh_terms: D001003:Anal Canal; D000818:Animals; D003050:Coccyx; D006651:Histocytochemistry; D051379:Mice; D009130:Muscle, Smooth / Q000378:metabolism* / Q000502:physiology; D009412:Nerve Fibers / Q000378:metabolism*; D018377:Neurotransmitter Agents / Q000378:metabolism; D010388:Pelvis / Q000294:innervation*; D011796:Quinacrine / Q000378:metabolism*
chemical_list: D018377:Neurotransmitter Agents; D011796:Quinacrine