title: [Immunohistochemical studies on non neoplastic and neoplastic gastric mucosa. Determination of embryonic and specific antigens (author's transl)].
abstract: The distributions of acid alpha1-glycoprotein, alpha1-fetoprotein, beta-galactosidase and gastrin in gastric carcinoma and gastric ulcer as well as in the neighbourhood of these lesions were studied by means of immunohistochemical methods on imprint preparation. We could not find significant differences between gastric carcinoma and the nonneoplastic lesions, except for the acid alpha1-glycoprotein. The results of this first study indicate that the immunochemical and immunohistological assay of acid alpha1-glycoprotein might be of practical value in diagnosing malignant changes of gastric mucosa.
mesh_terms: D000017:ABO Blood-Group System; D000818:Animals; D003110:Colonic Neoplasms / Q000276:immunology; D004381:Duodenal Ulcer / Q000276:immunology; D005455:Fluorescent Antibody Technique; D005696:Galactosidases / Q000032:analysis; D005753:Gastric Mucosa / Q000276:immunology*; D005755:Gastrins / Q000032:analysis; D006041:Goats; D006168:Guinea Pigs; D006651:Histocytochemistry; D006801:Humans; D010437:Peptic Ulcer / Q000276:immunology*; D011817:Rabbits; D013274:Stomach Neoplasms / Q000276:immunology*; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000017:ABO Blood-Group System; D005755:Gastrins; D000509:alpha-Fetoproteins; D005696:Galactosidases
vernacular_title: Immunhistochemische Studien an normaler und pathologischer Magenschleimhaut: Nachweis fetaler und magenschleimhautspezifischer Antigene