Amidino-substituted aromatic heterocycles as probes of the specificity pocket of trypsin-like proteases.
D000176:Acrosin / Q000037:antagonists & inhibitors; D000578:Amidines / Q000494:pharmacology*; D000818:Animals; D001667:Binding, Competitive; D002417:Cattle; D010450:Endopeptidases / Q000378:metabolism*; D005170:Factor X / Q000037:antagonists & inhibitors; D005341:Fibrinolysin / Q000037:antagonists & inhibitors; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007610:Kallikreins / Q000037:antagonists & inhibitors; D011480:Protease Inhibitors; D011485:Protein Binding; D013329:Structure-Activity Relationship; D013917:Thrombin / Q000037:antagonists & inhibitors; D014361:Trypsin Inhibitors
D000578:Amidines; D011480:Protease Inhibitors; D014361:Trypsin Inhibitors; D005170:Factor X; D010450:Endopeptidases; D007610:Kallikreins; D000176:Acrosin; D013917:Thrombin; D005341:Fibrinolysin