Maternal effects of regular salicylate ingestion in pregnancy.
6.6% of all Australian patients attending an antenatal clinic were found to be taking salicylate preparations regularly, most commonly in powder form and almost always as self-medication. In this group of salicylate takers there was an increased incidence of anaemia, anti-partum and post-partum haemorrhage, prolonged gestation, complicated deliveries, and perinatal mortality compared with non-takers. These findings suggest that regular salicylate consumption has detrimental effects in pregnancy. Routine antenatal urinary screening for salicylate in pregnancy is recommended.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000740:Anemia / Q000139:chemically induced; D005260:Female; D005313:Fetal Death / Q000139:chemically induced; D006801:Humans; D007231:Infant, Newborn; D007744:Obstetric Labor Complications / Q000139:chemically induced; D010298:Parity; D006473:Postpartum Hemorrhage / Q000139:chemically induced; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced*; D011250:Pregnancy Complications, Hematologic / Q000139:chemically induced; D011273:Pregnancy, Prolonged; D011446:Prospective Studies; D012459:Salicylates / Q000008:administration & dosage / Q000009:adverse effects*; D012651:Self Medication; D013997:Time Factors; D014592:Uterine Hemorrhage / Q000139:chemically induced
D012459:Salicylates