Hemolytic anemia caused by auto anti-N.
The second case of hemolytic anemia caused by auto anti-N, occurring in a 7-year-old boy, is described. The antibody was IgG, as shown by the use of specific anti-human IgG Coombs sera, failure of inactivation by 2-mercaptoethanol, and chromatographic separation on a G-200 Sephadex column.
D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood / Q000188:drug therapy / Q000276:immunology*; D001323:Autoantibodies; D001789:Blood Group Antigens; D002648:Child; D000939:Epitopes; D004912:Erythrocytes / Q000276:immunology; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D008623:Mercaptoethanol / Q000494:pharmacology; D011241:Prednisone / Q000627:therapeutic use
D001323:Autoantibodies; D001789:Blood Group Antigens; D000939:Epitopes; D006454:Hemoglobins; D007074:Immunoglobulin G; D008623:Mercaptoethanol; D011241:Prednisone