[Studies on the effect of oxprenolol on experimentally induced anxiety (author's transl)].
This experiment studied the question of whether the receptor blocking agent oxprenolol (20 mg) influences somatic and subjective responses to experimentally induced anxiety. 72 male students were Ss in a two-factorial design with type of drug (oxprenolol, placebo) and type of situation as the two factors. Anxiety was induced by the signaled application of shocks to one arm, under condition A with and under condition B without time control (clock available or not). Condition C was a control condition with neither shock nor time control. Heart rate, blood pressure and verbal reports of emotional experience were measured. An analysis of variance revealed the following: Oxprenolol showed physiological effects typical of a receptor blocking agent. The drug positively affected emotional experience not related to the experimentally induced anxiety but did not affect the emotional responses induced by the anxiety-provoking conditions. For explaining the results the possible meaning of the variable "internal vs external control of emotional responses" was considered.
D000328:Adult; D014151:Anti-Anxiety Agents; D001794:Blood Pressure / Q000187:drug effects; D004597:Electroshock; D004644:Emotions / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D010096:Oxprenolol / Q000494:pharmacology*
D014151:Anti-Anxiety Agents; D010096:Oxprenolol
Untersuchungen zur Wirkung von Oxprenolol auf experimentell induzierte Angst.