Immunotherapy of non-clinical vaginal cancer.
In six women who had had a hysterectomy and three or more vaginal smears positive for malignant cells but no symptoms, a course of immunotherapy, based on delayed hypersensitivity reaction to dinitrochlorobenzene, was tried. Repeat smears done every three months have all been normal, and the patients were well when last seen 2-35 months after treatment.
D004137:Dinitrochlorobenzene / Q000008:administration & dosage / Q000276:immunology* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed; D007167:Immunotherapy / Q000379:methods*; D009578:Nitrobenzenes / Q000276:immunology*; D014625:Vaginal Neoplasms / Q000473:pathology / Q000628:therapy*; D014626:Vaginal Smears
D004137:Dinitrochlorobenzene; D009578:Nitrobenzenes