[Experimental study of the catatoxic effects of steroid hormones].
Tests set up on mice and rats brought evidence that spironolactone, progesterone, testosterone-propionate, methylandostendiol, desoxycorticosterone-acetate, methyltosterone, diethylstilbestrol, preparation PCN, megesterol-acetate and mestranol disply a catatoxic action, whose degree depends upon the method of evaluation and the animal species. A pattern for selection of catatoxic agents is proposed and some aspects of their mode of action are discussed.
D000818:Animals; D004347:Drug Interactions; D005260:Female; D008099:Liver / Q000187:drug effects; D008620:Meprobamate / Q000633:toxicity; D051379:Mice; D008815:Mice, Inbred Strains; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D012890:Sleep / Q000187:drug effects; D013045:Species Specificity; D013256:Steroids / Q000494:pharmacology*; D013997:Time Factors
D013256:Steroids; D008620:Meprobamate
Eksperimental'noe izuchenie katatoksicheskikh éffektov steroidnykh gormonov