title: Another example of a B variant.
abstract: A family in which five members has a weak B variant and one member had a normal A and weak B reaction is reported. It appears that these phenotypes arise by the inheritance of a variant allele of the ABO locus. Their cells react weakly when added to anti-B sera, and they have normal anti-A activity and an absence of anti-B in their sera. Additionally, all of the members tested had increased levels of cellular H substance and all of the affected secretor members of the family secreted normal amounts of both B and H substance. Transferase activity of the sera of these individuals confirmed the presence of the B-gene specific transferase.
mesh_terms: D000017:ABO Blood-Group System; D000328:Adult; D000939:Epitopes; D005260:Female; D005796:Genes; D006801:Humans; D008297:Male; D010375:Pedigree; D012463:Saliva / Q000378:metabolism; D014166:Transferases / Q000097:blood
chemical_list: D000017:ABO Blood-Group System; D000939:Epitopes; D014166:Transferases