[The determination of phosphohexose isomerase in patients with cancer of breast and uterus. A comparison with other tests (author's transl)].
The levels of PHI are evaluated in 94 patients, who are classified by histological, scintigraphycal, radiological, biochemical and clinical test in: 16 patients, who suffer from some premalignant lesions of breast and uterus, 15 patients, who suffer from cancer of breast without metastases, 20 patients who suffer from cancer of breast with metastases, 18 patients who suffer from with cancer of uterus without metastases, 25 patients who suffer from cancer of uterus with metastases. The PHI activity is also evaluated in relation to the activity of other enzymes (LDH, AIP, G-GT). It has been revealed that: a) the PHI activity keeps within limits of normal value in patients who suffer from some pre-malignant lesions; b) all the patients suffer from cancer of breast without metastases show normal levels of PHI; c) in the patients with cancer of breast with metastases: 5 patients show normal levels of PHI, 5 patients show levels of PHI within limits, certainly 10 patients show pathological levels; d) in patients with cancer of uterus without metastases the value of enzymes results pathological in 6 patients, 6 patients show levels of PHI within limits that are above average and 6 patients show normal levels of PHI; e) the value of PHI always results high in patients with cancer of uterus with metastases.
D000469:Alkaline Phosphatase / Q000097:blood; D001943:Breast Neoplasms / Q000201:enzymology*; D005260:Female; D005956:Glucose-6-Phosphate Isomerase / Q000097:blood*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D009362:Neoplasm Metastasis / Q000201:enzymology; D011230:Precancerous Conditions / Q000201:enzymology*; D014594:Uterine Neoplasms / Q000201:enzymology*; D005723:gamma-Glutamyltransferase / Q000097:blood
D007770:L-Lactate Dehydrogenase; D005723:gamma-Glutamyltransferase; D000469:Alkaline Phosphatase; D005956:Glucose-6-Phosphate Isomerase
Determinazione della fosfoesosoisomerasi in corso di neoplasie della mammella e dell'utero. Raffronto con altri tests enzimatici.