Primary hepatic malignancy in pregnant women.
Three women dying from hepatic carcinoma during pregnancy are presented. One of these women with a hepatocellular carcinoma and alpha fetoprotein in the serum and antibody to hepatitis B antigen. A fourth patient died 2 months post partum with a cholangiocarcinoma. A false positive pregnancy test suggested that she had metastatic choriocarcinoma in the liver, and a panhysterectomy was performed. The clinical diagnosis with the use of alpha fetoprotein and chorionic gonadotropin for detection of hepatoma and the etiopathogenesis of primary hepatic malignancy in pregnancy are discussed.
D002759:Adenoma, Bile Duct / Q000097:blood / Q000401:mortality; D000328:Adult; D000510:Alpha-Globulins / Q000302:isolation & purification; D001344:Autopsy; D001706:Biopsy; D006528:Carcinoma, Hepatocellular / Q000097:blood / Q000401:mortality / Q000473:pathology; D005260:Female; D005313:Fetal Death; D005326:Fetal Proteins / Q000302:isolation & purification; D006511:Hepatitis B Antigens / Q000302:isolation & purification; D006801:Humans; D005779:Immunodiffusion; D007958:Leukocyte Count; D008099:Liver / Q000473:pathology; D008111:Liver Function Tests; D008113:Liver Neoplasms / Q000097:blood / Q000175:diagnosis / Q000401:mortality / Q000473:pathology; D008585:Meningitis, Meningococcal / Q000209:etiology; D009364:Neoplasm Recurrence, Local; D011247:Pregnancy; D011248:Pregnancy Complications; D011251:Pregnancy Complications, Infectious
D000510:Alpha-Globulins; D005326:Fetal Proteins; D006511:Hepatitis B Antigens