title: [Chronic lymphocytic leukaemia with cutaneous lesions and deafness following periarteritis nodosa (author's transl)].
abstract: A case is reported of a 49 years-old man who presented with cutaneous and muscular manifestations revealing periarteritis nodosa. Two years after detection of this disease occured a preleukemic condition and four years later a chronic lymphocytic leukaemia is discovered. In clinical course appeared a tuberous infiltration of the face and a sudden bilateral deafness. Regression of these two abnormalities is obtained after administration of prednisolone. The patient died of generalized infectious process postoperatively. From these clinical and pathological findings relations between periarteritis and CLL, occurence of deafness and cutaneous lesions are discussed. The relationship between the development of CLL and the immunosuppressive treatment is considered.
mesh_terms: D003638:Deafness / Q000209:etiology*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007634:Keratitis / Q000209:etiology; D007945:Leukemia, Lymphoid / Q000209:etiology*; D008297:Male; D008620:Meprobamate / Q000009:adverse effects; D008875:Middle Aged; D009135:Muscular Diseases / Q000209:etiology; D010034:Otitis Media with Effusion / Q000209:etiology; D010488:Polyarteritis Nodosa / Q000150:complications* / Q000175:diagnosis; D012871:Skin Diseases / Q000209:etiology*; D014657:Vasculitis / Q000209:etiology
chemical_list: D007166:Immunosuppressive Agents; D008620:Meprobamate
vernacular_title: Périartérite nouleuse suivie d'une leucémie lymphoide chronique avec lésions cutanées et surdité.