title: The effects of polyacrylic acid and virazole on the replication and component formation of red clover mottle virus.
abstract: Polyacrylic acid and Virazole inhibited the replication of red clover mottle virus (RCMV) in systemically infected pea (Pisum sativum) plants, as shown both by serological and infectivity tests. The Virazole-induced changes had little effect on the proportion of the three components in the total virus yield, but treatment with polyacrylic acid markedly increased the proportion of the RNA-free top component. This suggests that either viral RNA synthesis or RNA encapsidation was inhibited.
mesh_terms: D000179:Acrylates / Q000494:pharmacology*; D007887:Fabaceae / Q000382:microbiology; D010942:Plant Viruses / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D010946:Plants, Medicinal; D012367:RNA, Viral / Q000096:biosynthesis; D012254:Ribavirin / Q000494:pharmacology*; D012263:Ribonucleosides / Q000494:pharmacology*; D014779:Virus Replication / Q000187:drug effects*
chemical_list: D000179:Acrylates; D012367:RNA, Viral; D012263:Ribonucleosides; D012254:Ribavirin