Benztropine prophylaxis of dystonic reactions.
The effectiveness of antiparkinson medication for the prevention of drug induced dystonias has remained a question. Forty patients with acute psychosis who received high potency oral antipsychotic drugs were interviewed to determine the incidence of acute dystonia. An eleven-fold increase in dystonia was found in patients who received no prophylactic medication. Such prophylaxis appears effective in preventing acute dystonia.
D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001590:Benztropine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004421:Dystonia / Q000139:chemically induced / Q000517:prevention & control*; D005260:Female; D006220:Haloperidol / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010640:Phenothiazines; D012559:Schizophrenia / Q000188:drug therapy; D014326:Tropanes / Q000627:therapeutic use*
D014150:Antipsychotic Agents; D010640:Phenothiazines; D014326:Tropanes; D001590:Benztropine; D006220:Haloperidol