title: Mussel-associated viral hepatitis, type A: serological confirmation.
abstract: 7 members of a family of 14 developed acute viral hepatitis approximately one month after a family outing. Epidemiological investigation incriminated incompletely cooked mussels (Mytilus edulis) as the vehicle of infection and revealed a statistically significant difference in attack-rates between mussel-ingesters (70%) and non-ingesters (0%) (P=0-035). The aetiological role of hepatitis-A virus, suspected on epidemiological grounds, was serologically confirmed by the demonstration of rises in titres of serum-antibody to hepatitis-A antigen (serologically related to the MS-1 strain of hepatitis-A virus), determined by immune adherence haemagglutination.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000302:isolation & purification; D001219:Aspartate Aminotransferases / Q000097:blood; D001315:Australia; D001663:Bilirubin / Q000097:blood; D049872:Bivalvia; D002648:Child; D004196:Disease Outbreaks; D005260:Female; D006506:Hepatitis A / Q000097:blood / Q000209:etiology* / Q000235:genetics; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D014871:Water Microbiology
chemical_list: D000914:Antibodies, Viral; D001219:Aspartate Aminotransferases; D001663:Bilirubin