[Non-random position of homologous chromosomes (no. 9 and YY) in interphase nuclei of human fibroblasts (author's transl)].
The position of chromosomes No. 9 and of the Y chromosomes in interphase nuclei was observed by means of the Giemsa-11 staining and the quinacrine mustard fluorescence staining respectively. 3 fibroblast cultures from normal female persons and 1 culture from a person with the karyotype 47/XYY were used. The distance between the two homologous chromosomes was compared with the theoretical expected distance between two points which are randomly positioned in a circular area. The distance between the chromosomes No. 9 as well as between the two Y chromosomes is significantly smaller than expected with a random position. This tendency for a somatic association is stronger in the case of the two Y chromosomes than in the two chromosomes No. 9.
D002467:Cell Nucleus; D002478:Cells, Cultured; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D005347:Fibroblasts / Q000648:ultrastructure*; D005453:Fluorescence; D006801:Humans; D007621:Karyotyping; D008297:Male; D008433:Mathematics; D008938:Mitosis; D011796:Quinacrine; D012730:Sex Chromosomes; D013194:Staining and Labeling
D011796:Quinacrine
Nichtzufällige Verteilung homologer Chromosomen (nr. 9 und YY) in Interphasekeren menschlicher Fibroblasten