title: Vitamins and oral contraceptive use.
abstract: Reports concerning the interaction between steroidal contraceptives (the combined pill) and vitamins indicate that in users the mean serum-vitamin-A level is raised and the mean serum-vitamin-B2 (riboflavine), vitamin-B6 (pyridoxine), vitamine-C, folic-acid, and vitamin-B12 levels are reduced. Other vitamins have been insufficiently studied for comment. Biochemical evidence of co-enzyme deficiency has been reported for vitamin B2, vitamin B6, and folic acid. Clinical effects due to vitamin deficiency have been described for vitamin B6--namely, depression and impaired glucose tolerance. Folic-acid deficiency with megaloblastic anaemia has been reported in only 21 cases.
mesh_terms: D000749:Anemia, Megaloblastic / Q000139:chemically induced; D001205:Ascorbic Acid / Q000097:blood; D001361:Avitaminosis / Q000139:chemically induced*; D003067:Coenzymes / Q000097:blood; D003276:Contraceptives, Oral / Q000009:adverse effects* / Q000494:pharmacology; D003863:Depression / Q000139:chemically induced; D005260:Female; D005494:Folic Acid Deficiency / Q000139:chemically induced; D005951:Glucose Tolerance Test; D006801:Humans; D011736:Pyridoxine / Q000097:blood; D012256:Riboflavin / Q000097:blood; D014801:Vitamin A / Q000097:blood; D014805:Vitamin B 12 / Q000097:blood; D026681:Vitamin B 6 Deficiency / Q000139:chemically induced / Q000150:complications
chemical_list: D003067:Coenzymes; D003276:Contraceptives, Oral; D014801:Vitamin A; D011736:Pyridoxine; D014805:Vitamin B 12; D001205:Ascorbic Acid; D012256:Riboflavin