title: [Central organization of transmitter systems].
abstract: The organisation of the central nervous system (CNS) is considered from the point of view of the chemical specificity of neurons with respect to their neurotransmitters. The mechanisms of neurotransmission are summarized as well as the approaches used to determine the neurotransmitters of specific CNS pathways. As an example, the neurotransmitters of the basal ganglion and their interactions are presented and their implications for the pathophysiology of Huntington disease and possibly schizophrenia are discussed.
mesh_terms: D001479:Basal Ganglia / Q000033:anatomy & histology; D002490:Central Nervous System / Q000033:anatomy & histology*; D006801:Humans; D006816:Huntington Disease / Q000503:physiopathology; D009434:Neural Pathways / Q000033:anatomy & histology; D009474:Neurons / Q000166:cytology / Q000201:enzymology; D018377:Neurotransmitter Agents / Q000378:metabolism* / Q000502:physiology; D012559:Schizophrenia / Q000503:physiopathology; D009435:Synaptic Transmission
chemical_list: D018377:Neurotransmitter Agents
vernacular_title: Organisation centrale des systèmes de transmetteurs.