title: Anomalous refractivity changes of gramicidin A in ethanol solutions.
abstract: Studies of the refractive properties of Gramicidin A in absolute ethanol and in ethanol water mixtures showed that this peptide in solution undergoes a conformational transition resulting in species with different refractivity. Accordingly, the folded form of this peptide shows a lower specific refractive index increment than the unfolded form. In addition, the occurrence of a strong pressure dependence of the transition is documented.
mesh_terms: D001665:Binding Sites; D000431:Ethanol; D006096:Gramicidin; D008968:Molecular Conformation; D014461:Ultracentrifugation
chemical_list: D006096:Gramicidin; D000431:Ethanol