[Protein-analytical studies on the serum and urine of patients with visceral lupus erythematosus].
Serum and urine of patients with ascertained lupus erythematodes visceralis were separated by means of the polyacrylamide gel pore gradient electrophoresis on the same experimental conditions. Deviations from the normal electropherogram were found in the serum within the gamma-globulins. For the demonstration of antinuclear factors the loose body test, the LE-cell test as well as the immunofluorescence test were carried out. In the uropherogram a highly molecular protein band could be proved which did not appear in the serum. In this fraction an immune complex which developed in the area of the kidney might be in question. It is referred to the possibility of the use of the PAA-polyacrylamide gel electrophoresis for the early recognition of renal changes.
D000974:Antibodies, Antinuclear / Q000652:urine; D000917:Antibody Formation; D001797:Blood Protein Electrophoresis; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007075:Immunoglobulin M / Q000302:isolation & purification; D008074:Lipoproteins / Q000378:metabolism; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000378:metabolism* / Q000652:urine; D008259:Macroglobulins / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*; D014168:Transferrin / Q000378:metabolism; D005719:gamma-Globulins / Q000302:isolation & purification
D000974:Antibodies, Antinuclear; D007075:Immunoglobulin M; D008074:Lipoproteins; D008259:Macroglobulins; D011506:Proteins; D014168:Transferrin; D005719:gamma-Globulins
Proteinanalytische Untersuchungen in Serum and Harn bei Patienten mit Lupus erythematodes visceralis