title: Synthesis of some alkoxybenzamide derivatives as smooth muscle relaxant agents.
abstract: The preparation of 16 new N-substituted p-aminobenzamide derivatives which contain diethylaminoethyl-N-methylpiperazine, piperidine and morpholine moieties were described. Preliminary pharmacological testing of representative compounds showed that some of the prepared compounds possess anticholinergic and antihistaminic activities.
mesh_terms: D000818:Animals; D001549:Benzamides / Q000138:chemical synthesis* / Q000494:pharmacology; D006168:Guinea Pigs; D006634:Histamine H1 Antagonists; D066298:In Vitro Techniques; D008722:Methods; D009119:Muscle Contraction / Q000187:drug effects*; D009126:Muscle Relaxation / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects*; D010276:Parasympatholytics
chemical_list: D001549:Benzamides; D006634:Histamine H1 Antagonists; D010276:Parasympatholytics