title: Perinatal mortality and birth-weight in relation to aspirin taken during pregnancy.
abstract: In a cohort of 41 337 gravidas and their offspring in the U.S.A. there was no evidence that aspirin taken in pregnancy is a cause of stillbirth, neonatal death, or reduced birth-weight. The women were divided into those who were not exposed to aspirin (14 956), those with intermediate exposure (24 866), and those who were heavily exposed (1515). Stillbirth-rates were similar for all three groups. Differences in neonatal death-rates and mean birth-weights were slight and none were statistically significant. Trends were opposite among approximately equal numbers of White and Black children.
mesh_terms: D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects*; D001724:Birth Weight / Q000187:drug effects*; D044383:Black People; D005260:Female; D005313:Fetal Death / Q000139:chemically induced*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000401:mortality*; D008431:Maternal-Fetal Exchange; D010298:Parity; D011247:Pregnancy; D012907:Smoking / Q000150:complications; D044465:White People
chemical_list: D001241:Aspirin