title: Experimental transmission of Tahyna virus (California group) to wild rabbits (Oryctolagus cuniculus) by mosquitoes.
abstract: Two wild rabbits (Oryctolagus cuniculus) were subcutaneously infected with a dose of 2.6 dex. i.c. LD50/0.02 ml of extraneurally passaged Tahyna virus strain "236". During the 24-72 hours interval p.i. viremia was demonstrated in both animals ranging from 1.0 to 3.42 dex. i.e. LD50/0.02. Mosquitoes Aedes vexans, which had fed on them, transmitted the virus to one of three other rabbits. During 24-96 hours interval after terminated feeding of infectious mosquitoes viremia was detected in this animal ranging from 0.49 to 4.08 dex i.c. LD50/0.02 ml. Seroconversion was revealed by means of plaque reduction neutralization test 11 days after infection.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D009033:Culicidae; D002141:Encephalitis Virus, California / Q000276:immunology / Q000302:isolation & purification; D004671:Encephalitis, Arbovirus / Q000635:transmission*; D004670:Encephalitis, California / Q000276:immunology / Q000382:microbiology / Q000635:transmission*; D005260:Female; D007303:Insect Vectors; D008297:Male; D011817:Rabbits
chemical_list: D000914:Antibodies, Viral