Amygdala and masseteric reflex. II Mechanism of the diphasic modifications of the reflex elicited from the "defence reaction area". Role of the spinal trigeminal nucleus (pars oralis).
It has been demonstrated (Gary Bobo and Bonvallet 1975) that long-lasting stimulation of the "amygdaloid area for the defence reaction" (basal nucleus, pars magnocellularis) elicits, after an initial facilitation, a delayed inhibition of the monosynaptic masseteric reflex (MR), while stimulation of the amygdalofugal fibers running in the ansa lenticularis provokes an immediate inhibition of the reflex. In present study, the structure which mediates these inhibitions has been identified. Using combined techniques of limited transections, localized coagulations and localized stimulation and recording, it has been demonstrated that these ingibitions are mediated by the rostral portion of the spinal trigeminal nucleus, the subnucleus oralis (NO). After localized coagulation of this nucleus, or after lesions which interrupt slectively the connections between the NO and the masticatory nucleus, long-lasting stimulation of the basal nucleus elicits only well maintained facilitation of the MR. Hence, the delayed decrease in amplitude of the reflex, observed during stimulation of the basal nucleus in the preparations with intact brain, cannot be explained by the reversal of an initial facilitatory influence to an ingibitory one. The one ingibition of the reflex is due to the superimposition, on a background of sustained facilitation of the masseteric motoneurons, of the inhibitory influence exerted on the monosynaptic masseteric circuit by a trigeminal sensory nucleus, itself activated by delayed discharges of the basal nucleus. A tentative representation of the dual control exerted on the masseteric activity by the basal nucleus is given in Fig. 9. The functional implications of this dual control during the "defence reaction" are briefly discussed.
D000679:Amygdala / Q000502:physiology*; D000818:Animals; D001931:Brain Mapping; D002415:Cats; D005071:Evoked Potentials; D008410:Masticatory Muscles / Q000294:innervation*; D009433:Neural Inhibition; D009434:Neural Pathways; D012023:Reflex, Monosynaptic; D012154:Reticular Formation / Q000502:physiology; D014276:Trigeminal Nerve / Q000502:physiology*