title: Initiation of DNA synthesis by the avian oncornavirus RNA-directed DNA polymerase: tryptophan tRNA as the major species of primer RNA.
abstract: The major species of primer RNA required for the initiation of DNA synthesis by the Rous sarcoma virus RNA-directed DNA polymerase can be aminoacylated by tryptophan. Furthermore, an intact 3' terminus is required for the primer to function in the initiation of DNA synthesis.
mesh_terms: D001358:Avian Sarcoma Viruses / Q000201:enzymology* / Q000378:metabolism; D002474:Cell-Free System; D004279:DNA, Viral / Q000096:biosynthesis*; D008715:Methionine / Q000378:metabolism; D008718:Methionine-tRNA Ligase / Q000378:metabolism; D012343:RNA, Transfer / Q000378:metabolism*; D012367:RNA, Viral / Q000378:metabolism*; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism*; D013698:Templates, Genetic; D014364:Tryptophan / Q000378:metabolism*; D014369:Tryptophan-tRNA Ligase / Q000378:metabolism
chemical_list: D004279:DNA, Viral; D012367:RNA, Viral; D014364:Tryptophan; D012343:RNA, Transfer; D008715:Methionine; D012194:RNA-Directed DNA Polymerase; D008718:Methionine-tRNA Ligase; D014369:Tryptophan-tRNA Ligase