title: [Treatment of chronic bronchitis with Supristol and a cotrimoxazole preparation--comparative bacteriological and clinical findings, results of a double-blind study (author's transl)].
abstract: In a randomized double-blind study on the treatment of chronic bronchitis, Supristol (co-trifamole) was compared with co-trimoxazole. 163 patients participated in the clinical trial that was performed at three different hospitals in accordance with a uniform trial plan. The microbiological investigations were done centrally at a hygiene institute for all three hospitals. The bacteriological results from the 61 patients whose antibiogram revealed sensitive pathogens before starting the therapy demonstrate the equal effectivenesss of the two preparations. With Supristol there was an elimination rate of 95.3%, and with co-trimoxazole of 93.2%. The clinical parameters do not show any difference in effectiveness either.
mesh_terms: D001991:Bronchitis / Q000188:drug therapy*; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004338:Drug Combinations; D006193:Haemophilus influenzae / Q000187:drug effects; D006801:Humans; D013296:Streptococcus pneumoniae / Q000187:drug effects; D013420:Sulfamethoxazole / Q000627:therapeutic use; D013423:Sulfamoxole / Q000627:therapeutic use*; D014295:Trimethoprim / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D014295:Trimethoprim; D013423:Sulfamoxole; D013420:Sulfamethoxazole
vernacular_title: Zur Behandlung der chronischen Bronchitis mit Supristol und einem Cotrimoxazolpräparat.