title: Neutrophil granules: A review.
abstract: Hematologists are familiar with the granules of leukocytes because they serve as a means of identification of certain white blood cells.19 It is now generally appreciated that the granules of neutrophilic polymorphonuclear leukocytes (PMN) store antibacterial agents and lysosomal enzymes until they are needed for the killing and digestion of phagocytized microorganisms.16 Within the framework of this well-known setting, this article presents some new data on the mode of formation and chemical content of PMN granules. In particular, the traditional view that azurophil (nonspecific) granules change into specific granules will be challenged.
mesh_terms: D000818:Animals; D001773:Blood Cells / Q000166:cytology; D001854:Bone Marrow Cells; D002415:Cats; D003094:Collagen; D004285:Dogs; D006098:Granulocytes / Q000166:cytology; D006168:Guinea Pigs; D000882:Haplorhini; D006801:Humans; D008247:Lysosomes / Q000201:enzymology; D008322:Mammals / Q000097:blood; D051379:Mice; D009504:Neutrophils / Q000166:cytology*; D009893:Opossums / Q000097:blood; D010586:Phagocytes / Q000382:microbiology; D011817:Rabbits; D013194:Staining and Labeling
chemical_list: D003094:Collagen