Effect of anticonvulsant drugs on urinary excretion of gamma-glutamyl transferase in women.
Excretion of gamma-glutamyl transferase was found to be significantly higher in a group of epileptic patients on long-term anticonvulsant therapy than in normal subjects. The losses, which may reflect renal enzyme induction, were unrelated to drug dose or duration of therapy and were significantly lower than those found in normal healthy pregnant women at term.
D000927:Anticonvulsants / Q000627:therapeutic use; D004827:Epilepsy / Q000188:drug therapy / Q000201:enzymology; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D012737:Sex Factors; D005723:gamma-Glutamyltransferase / Q000652:urine*
D000927:Anticonvulsants; D005723:gamma-Glutamyltransferase