Glucagon resistance as a case of hypertriglyceridaemia.
The hypothesis that glucagon resistance is a cause of hypertriglyceridaemia has been tested by studying the effects of exogenous glucagon in patients with hypertriglyceridaemia and controls. Glucagon and a greater triglyceride-lowering-effect in hypertriglyceridaemic patients than in controls. The other metabolic response to glucagon were similar in both groups. No evidence of glucagon resistance was found.
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D003864:Depression, Chemical; D004351:Drug Resistance; D005260:Female; D005934:Glucagon / Q000494:pharmacology*; D006801:Humans; D008099:Liver / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000096:biosynthesis / Q000097:blood*
D001786:Blood Glucose; D014280:Triglycerides; D005934:Glucagon