[Pharmacotoxic psychoses in patients with neurological disorders during old age (author's transl)].
23.3 per cent out of 180 old patients (age above 60 years, 71 y in the mean) suffering from chronic cerebral disorders (3 large groups of disease) developed pharmacotoxic psychoses. This relative high percentage can be explained by psychotoxic side effects of the modern antiparkinson-therapy. The incidence to psychotoxicity of combined L-Dopa seems to be less marked in patients without Parkinson's disease when compared to patients with progredient nigrostriatal degeneration. Toxic delirium as a result of treatment with antidepressants, diuretics and digitalis was observable only in a few percentage. This occurance was even less pronounced in comparison to acute developing exogene psychoses in the same group of patients when drugs were not administered.
D000368:Aged; D000928:Antidepressive Agents / Q000009:adverse effects; D000978:Antiparkinson Agents / Q000009:adverse effects*; D014150:Antipsychotic Agents / Q000009:adverse effects; D001927:Brain Diseases / Q000150:complications / Q000188:drug therapy; D004071:Digitalis Glycosides / Q000009:adverse effects; D004232:Diuretics / Q000009:adverse effects; D006801:Humans; D007980:Levodopa / Q000009:adverse effects; D008875:Middle Aged; D011605:Psychoses, Substance-Induced / Q000209:etiology*; D011619:Psychotropic Drugs / Q000009:adverse effects*
D000928:Antidepressive Agents; D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D004071:Digitalis Glycosides; D004232:Diuretics; D011619:Psychotropic Drugs; D007980:Levodopa
Medikamentös ausgelöste Psychosen bei neurologisch erkrankten älteren Menschen.