title: Effect of chlorhexidine on acidogenicity of dental plaque in vivo.
abstract: In order to evaluate the effect of chlorhexidine on the acidogenicity of dental plaque, pH changes in plaque were measured in situ after sucrose applications. The results showed that a 0.2% chlorhexidine mouthrinse inhibited acid production for a period of 24 h, whereas a 0.05% chlorhexidine rinse showed an inhibitory effect for 4 h. It is suggested that the mechanism involved may be related to the retention of chlorhexidine in the mouth and in plaque providing a bacteriostatic milieu which may be of importance in the observed long-term effect.
mesh_terms: D000328:Adult; D002710:Chlorhexidine / Q000494:pharmacology*; D003773:Dental Plaque / Q000517:prevention & control*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D009067:Mouthwashes; D009910:Oral Hygiene; D013395:Sucrose / Q000494:pharmacology
chemical_list: D009067:Mouthwashes; D013395:Sucrose; D002710:Chlorhexidine