Synthetic antigens. Horse "natural" antibodies against interpolymer of styrene and maleic acid (PSM).
Properties of horse natural anti-PSM antibodies are described. The antibodies were of IgG class. Electrostatic forces were mainly involved in reaction of PSM with horse antibodies. The reaction was inhibited by low molecular compounds resembling structural unit of PSM. Studies of difference spectra and ORD and CD spectra showed no major conformational changes in horse antibodies after reaction with PSM.
D000818:Animals; D000918:Antibody Specificity; D000941:Antigens; D006736:Horses / Q000276:immunology*; D006863:Hydrogen-Ion Concentration; D007074:Immunoglobulin G; D008298:Maleates / Q000276:immunology*; D009994:Osmolar Concentration; D011137:Polystyrenes / Q000276:immunology*; D011233:Precipitin Tests; D013056:Spectrophotometry, Ultraviolet; D013696:Temperature
D000941:Antigens; D007074:Immunoglobulin G; D008298:Maleates; D011137:Polystyrenes