Localization of growth hormone-release-inhibiting hormone (somatostatin) in the rat brain.
Utilizing an immunoperoxidase technique at the light microscope level, growth hormone-release-inhibiting hormone (somatostatin) was localized in the external zone of the median eminence, the subcommissural organ, the organum vasculosum of the lamina terminalis and the pineal gland. No positive reaction was detected in any other brain area.
D000818:Animals; D001923:Brain Chemistry; D013007:Growth Hormone-Releasing Hormone / Q000037:antagonists & inhibitors*; D007031:Hypothalamus / Q000032:analysis; D007106:Immune Sera; D007120:Immunochemistry; D008297:Male; D008473:Median Eminence / Q000032:analysis; D010455:Peptides / Q000302:isolation & purification*; D010477:Perfusion; D010544:Peroxidases; D010870:Pineal Gland / Q000032:analysis; D011817:Rabbits / Q000276:immunology; D051381:Rats; D011919:Rats, Inbred Strains; D013194:Staining and Labeling
D007106:Immune Sera; D010455:Peptides; D013007:Growth Hormone-Releasing Hormone; D010544:Peroxidases