title: Genotypological method of analysis of individual responsiveness of an organism in experiment.
abstract: The principle of a genotypological method of analysis of individual responsiveness of an organism in experiment is formulated on the basis of data in the literature and the results of the author's own investigations. The main objective of a genotypological method is the determination of the constitutional typological features of responsiveness and their markers on the basis of similar or different norms of reaction and paratypical factors. It is proposed that individual responsiveness in a population be determined by way of disclosing in individuals the corresponding markers previously established in linear and non-linear animals in experiment, while observing a number of necessary conditions. These markers, capable of playing the role of indicators of a "constitutional typological reaction norm" and also of an individual reaction norm with respect to a concrete agent, are called genotypological markers.
mesh_terms: D000818:Animals; D000830:Animals, Laboratory / Q000235:genetics / Q000502:physiology; D001824:Body Constitution; D005838:Genotype; D009424:Nervous System Physiological Phenomena; D018377:Neurotransmitter Agents / Q000502:physiology; D010827:Physiology; D051381:Rats; D012106:Research
chemical_list: D018377:Neurotransmitter Agents