Normal serum-lipids in renal-transplant patients.
In contrast to previous reports, most patients (78%) with a successful renal transplant being followed up at the University of Kentucky Medical Center had a normal serum-lipid profile. The patients with hyperlipidaema (22%) had normal fasting insulin levels; they received similar immunosuppressive therapy but were significantly older and more obese than those with normal lipids. This lower prevalence of hyperlipidaemia and the absence of fasting hyperinsulinaemia are tentatively attributed to the use of alternate-day corticosteroid therapy in stable renal-transplant patients. If confirmed, the relative infrequency of hyperlipidaemia in patients of alternate-day corticosteroid therapy would be an additional advantage of that therapy over a daily regimen.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000941:Antigens; D001379:Azathioprine / Q000008:administration & dosage / Q000627:therapeutic use; D001835:Body Weight; D002784:Cholesterol / Q000097:blood; D003401:Creatine / Q000097:blood; D005215:Fasting; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000139:chemically induced / Q000209:etiology; D007328:Insulin / Q000097:blood; D016030:Kidney Transplantation; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D014184:Transplantation, Homologous; D014280:Triglycerides / Q000097:blood
D000941:Antigens; D007328:Insulin; D008055:Lipids; D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol; D001379:Azathioprine; D003401:Creatine; D011241:Prednisone