[Characteristics of the lymphoid tissue reaction in compensatory reparative growth of the salivary glands in mice].
The capacity of the spleen cells of CBA mice to antibody formation as well as to the "graft-versus-host" (GVH) reaction and the change in the stem cell number determined by the spleen colony method were studied after unilateral removal or burn of the submandibular salivary gland and amputation of lower incisors. It is shown that any of these experimental changes in the salivary gland state causes an increase in the stem cell migration and makes lymphocytes more active in inducing the GVH reaction. The ability of spleen lymphocytes to react on additional antigen stimuli increases after amputation of lower incisors, accompanied by an enlargement of salivary glands, and sharply decreases after the removal or burn of the submandibular salivary gland, not causing hypertrophy of salivary glands.
D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology; D006087:Graft vs Host Reaction; D006462:Hemolytic Plaque Technique; D008221:Lymphoid Tissue / Q000276:immunology*; D051379:Mice; D008808:Mice, Inbred CBA; D012038:Regeneration; D013154:Spleen / Q000276:immunology; D013363:Submandibular Gland / Q000254:growth & development* / Q000276:immunology
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