Serum free fatty acid level and body temperature changes in emotional stress in rabbits. Effect of hydroxydial.
Fourteen New Zealand rabbits were immobilized for 75 minutes During this time the ear (Te) and rectal (Tre) temperatures were measured at 5 min intervals. Immediately before immobilization, and then in the 35th, 55th, and 75th min of immobilization blood samples were taken for determinations of the serum free fatty acid (FFA) levels. A statistically significant fall of Tre and a significant rise in the serum FFA levels were observed at the end of immobilization. The ear temperature in these animals exceeded considerably the values as normal. Intravenous administration of hydroxydial 0.1 mg/kg before repeated immobilization prevented body temperature changes and blood FFA level rise in half the animals. In the remaining animals the changes became more intensive. It is supposed that the tested rabbits differed in their reactivity to stressful stimuli, and this hypothesis was confirmed by experiments in which weaker stimuli were used. Repetition of stressful stimuli increased the intensity of these autonomic responses in all animals.
D000818:Animals; D001463:Barbiturates / Q000494:pharmacology*; D001831:Body Temperature / Q000187:drug effects; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D006801:Humans; D007103:Immobilization; D008297:Male; D011817:Rabbits; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000097:blood*
D001463:Barbiturates; D005230:Fatty Acids, Nonesterified