title: Carcinoma of the thoraco-abdominal oesophagus.
abstract: A new approach in the management of carcinoma of the thoraco-abdominal oesophagus, by means of pre-operative chemotherapy, in the form of Methotrexate and irradiation, followed by a one-stage resection, using a thoracic/abdominal approach, is described. This resulted in a marked tumour regression without leading to difficulty with operative management.
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000601:surgery / Q000628:therapy*; D003037:Cobalt Radioisotopes; D004938:Esophageal Neoplasms / Q000601:surgery / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D010166:Palliative Care; D011182:Postoperative Care; D011300:Preoperative Care; D011867:Radioisotope Teletherapy
chemical_list: D003037:Cobalt Radioisotopes; D008727:Methotrexate