title: Synthesis, assignment of absolute configuration, and receptor binding studies relevant to the neuroleptic activities of a series of chiral 3-substituted cyproheptadine atropisomers.
mesh_terms: D000818:Animals; D014150:Antipsychotic Agents; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D003533:Cyproheptadine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D008968:Molecular Conformation; D051381:Rats; D011942:Receptors, Adrenergic, alpha / Q000378:metabolism; D011954:Receptors, Dopamine / Q000378:metabolism; D011955:Receptors, Drug / Q000378:metabolism; D011976:Receptors, Muscarinic / Q000378:metabolism; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D014150:Antipsychotic Agents; D011942:Receptors, Adrenergic, alpha; D011954:Receptors, Dopamine; D011955:Receptors, Drug; D011976:Receptors, Muscarinic; D003533:Cyproheptadine