[Proliferative reaction in the lymph node of recipients after the transplantation of the splenic cells of burned syngeneic donors].
Thermal burn was shown to induce in the splenocyte population in mice the appearance of cells capable of producing proliferative reaction in the regional lymph node. Spleen cells taken on days 1--2 after a burn were found to be most active. A direct relation between the number of transplanted cells and marked proliferation process in the lymph node was established. The proliferative process was mainly the consequence of the proliferation of donor cells. The process resulted, probably, either from the stimulation of cell division under the influence of proliferation factors, or from the activization of autoreactive lymphocyte clones.
D000818:Animals; D002056:Burns / Q000503:physiopathology*; D002455:Cell Division; D006087:Graft vs Host Reaction; D008198:Lymph Nodes / Q000166:cytology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D013154:Spleen / Q000528:radiation effects / Q000637:transplantation*; D013997:Time Factors; D014019:Tissue Donors; D014185:Transplantation, Isogeneic
Proliferativnaia reaktsiia v limfaticheskom uzle intaktnykh retsipientov posle transplantatsii selezenochnykh kletok obozhzhennykhsingennykh donorov.