Template primer inactivation by cis- and trans-dichlorodiammine platinum for human DNA polymerase alpha, beta, and Rauscher murine leukemia virus reverse transcriptase, as a mechanism of cytotoxicity.
D002460:Cell Line; D002945:Cisplatin / Q000494:pharmacology*; D004254:DNA Nucleotidyltransferases / Q000378:metabolism*; D008214:Lymphocytes / Q000378:metabolism; D011089:Polydeoxyribonucleotides / Q000378:metabolism; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism*; D011925:Rauscher Virus / Q000201:enzymology; D013054:Spectrophotometry, Atomic; D013329:Structure-Activity Relationship; D013698:Templates, Genetic
D011089:Polydeoxyribonucleotides; D004254:DNA Nucleotidyltransferases; D012194:RNA-Directed DNA Polymerase; D002945:Cisplatin