The effects of polyacrylic acid and virazole on the replication and component formation of red clover mottle virus.
Polyacrylic acid and Virazole inhibited the replication of red clover mottle virus (RCMV) in systemically infected pea (Pisum sativum) plants, as shown both by serological and infectivity tests. The Virazole-induced changes had little effect on the proportion of the three components in the total virus yield, but treatment with polyacrylic acid markedly increased the proportion of the RNA-free top component. This suggests that either viral RNA synthesis or RNA encapsidation was inhibited.
D000179:Acrylates / Q000494:pharmacology*; D007887:Fabaceae / Q000382:microbiology; D010942:Plant Viruses / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D010946:Plants, Medicinal; D012367:RNA, Viral / Q000096:biosynthesis; D012254:Ribavirin / Q000494:pharmacology*; D012263:Ribonucleosides / Q000494:pharmacology*; D014779:Virus Replication / Q000187:drug effects*
D000179:Acrylates; D012367:RNA, Viral; D012263:Ribonucleosides; D012254:Ribavirin