Assay for type C virus in mouse sera based on particulate reverse transcriptase activity.
Assay of particulate reverse transcriptase activity in the sera from feral mice naturally infected with type C virus provides a sensitive and rapid procedure for the determination of in vivo virus infection. The results compare well with assays for infectious virus and with complement fixation or competitive radio-immunoassays for the p30 internal antigen of the virus.
D000818:Animals; D003168:Complement Fixation Tests; D005069:Evaluation Studies as Topic; D017988:Gammaretrovirus / Q000201:enzymology*; D051379:Mice; D012194:RNA-Directed DNA Polymerase / Q000097:blood*; D011863:Radioimmunoassay; D012190:Retroviridae / Q000201:enzymology*; D014412:Tumor Virus Infections / Q000175:diagnosis*
D012194:RNA-Directed DNA Polymerase