[Sympathetic control on salivary secretion by the parotid gland in rabbit. II. Effects upon the gland submitted to a weak parasympathetic stimulation (author's transl)].
Superior cervical ganglion stimulation significantly increases both, flow and amylase activity of saliva. Stimulation provokes two markedly different periods of flow: during the first half, flow is very high and differs significantly from the flow of the second half which closely resembles the one previous to stimulation. Alpha-adrenergic blocking agents, when administered intravenously, abolish the hypersecretion induced by sympathetic stimulation; beta-adrenergic blocking agents do not. These facts strengthen the hypothesis that alpha-adrenoceptors are most important in fluid secretion. The infusion of epinephrine acts similarly on cervical ganglion stimulation, but it differs because of its more diffuse effects and deeper cardiovascular alterations. Isoproterenol, after a long latency period, slightly increases salivary flow, which seemingly indicates that beta-adrenoceptors are involved in the fluid secretory processes although in a lesser degree than alpha-adrenoceptors.
D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology*; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000681:Amylases / Q000032:analysis; D000818:Animals; D010306:Parotid Gland / Q000378:metabolism*; D011817:Rabbits; D012463:Saliva / Q000201:enzymology / Q000378:metabolism*; D013268:Stimulation, Chemical; D013564:Sympathetic Nervous System / Q000502:physiology*; D013997:Time Factors
D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D000681:Amylases
Influencias simpáticas sobre la secreción de saliva por la parótida del conejo II. Efectos sobre la glándula sometida a estimulación parasimpática débil.