Role of calcium in ethanol-membrane interactions: a model for tolerance and dependence.
The calcium content of membranes may regulate a number of key neuronal processes. Studies are described in which acute and chronic administration of ethanol was shown to alter calcium binding to synaptosomal plasma membranes.
D000437:Alcoholism / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000187:drug effects; D002118:Calcium / Q000378:metabolism*; D004361:Drug Tolerance; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D008560:Membrane Fluidity / Q000187:drug effects; D008563:Membrane Lipids / Q000378:metabolism; D018377:Neurotransmitter Agents / Q000378:metabolism; D017981:Receptors, Neurotransmitter / Q000187:drug effects / Q000378:metabolism; D013570:Synaptic Membranes / Q000187:drug effects / Q000378:metabolism*
D008563:Membrane Lipids; D018377:Neurotransmitter Agents; D017981:Receptors, Neurotransmitter; D000431:Ethanol; D002118:Calcium