Infective transmission and characterisation of a C-type virus released by cultured human myeloid leukaemia cells.
A C-type virus isolated from long term cultures of myeloid cells from a patient with acute myelogenous leukaemia is infectious for a wide variety of cells. The establishment of chronically infected cells enabled us to characterise the virus by biological, immunological, and biochemical tests. The virus is closely related to the simian sarcoma-associated virus isolated from a woolly monkey fibrosarcoma.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002460:Cell Line; D002685:Chiroptera; D006224:Cricetinae; D003429:Cross Reactions; D004285:Dogs; D005354:Fibrosarcoma / Q000382:microbiology; D000882:Haplorhini; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000382:microbiology*; D008907:Mink; D011784:Quail; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D012190:Retroviridae / Q000201:enzymology / Q000254:growth & development / Q000276:immunology / Q000302:isolation & purification*; D012208:Rhabdomyosarcoma / Q000382:microbiology; D012526:Satellite Viruses / Q000276:immunology; D010948:Viral Plaque Assay; D014764:Viral Proteins / Q000276:immunology; D014779:Virus Replication
D000956:Antigens, Viral; D014764:Viral Proteins; D012194:RNA-Directed DNA Polymerase