Antilymphocyte globulin in the treatment of advanced Sézary syndrome.
Two patients with Sézary syndrome, refractory to conventional treatment, were given cyclophosphamide and antilymphocyte globulin (A.L.G) Both patients showed improvement. One patient subsequently died from widespread varicella and the other relapsed later. It is concluded that A.L.G. may be effective in this condition.
D000328:Adult; D000368:Aged; D000961:Antilymphocyte Serum / Q000008:administration & dosage / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use; D003873:Dermatitis, Exfoliative / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D005260:Female; D006801:Humans; D007104:Immune Adherence Reaction; D007645:Keratoderma, Palmoplantar / Q000097:blood / Q000188:drug therapy / Q000276:immunology; D037102:Lectins / Q000494:pharmacology; D008206:Lymphatic Diseases / Q000097:blood / Q000276:immunology / Q000628:therapy*; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D013577:Syndrome; D013601:T-Lymphocytes / Q000276:immunology
D000961:Antilymphocyte Serum; D037102:Lectins; D003520:Cyclophosphamide