[Seroepidemiologic studies on reovirus infections of man, domestic and wild animals in Tanzania (author's transl)].
2238 sera of bovines, 95 of goats, 251 of antelopes (various species), 143 of zebras and 11 of warthogs collected in Tanzania as well as 811 sera of men and females of the city and the region of Dar es Salaam were tested for haemagglutination inhibiting antibodies (Ab) to reovirus serotypes (St) 1, 2 and 3. Ab to St 1 resp. 2 could be detected in 24--39% of bovines, goats, antelopes and zebras, and in warthogs to 64%. In human beings the positive percentage was 60%. Ab to St 3 were most prevalent: Sera of domestic animals were positive in 70--84%, of wild animals in 77--100% and of the human population in 91%. These figures include the occurrence of Ab to one St alone as well as to more than one St. A further analysis showed, that Ab to St 3 are definitely dominant especially in sera of animals, whereas the simultaneous occurrence of Ab to all 3 St was more frequently observed in sera of human beings. Other Ab-type combinations were apparently of far less importance. It seems to be significant that the highest infection rate was found in humans (except zebras and warthogs) and that their contact to animals did not result in a higher Ab conversion rate as without such a possibility. The results were discussed under seroepidemiologic aspects and it is concluded that reovirus infections are facultative viral zoonoses.
D000293:Adolescent; D000328:Adult; D000818:Animals; D000829:Animals, Domestic; D000835:Animals, Wild; D000914:Antibodies, Viral / Q000032:analysis; D005260:Female; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology; D012087:Reoviridae / Q000276:immunology; D012088:Reoviridae Infections / Q000453:epidemiology* / Q000276:immunology / Q000662:veterinary; D013636:Tanzania; D015047:Zoonoses
D000914:Antibodies, Viral
Serologische Untersuchungen zur Epidemiologie von Reovirus-infektionen bei Menschen, Nutz- und Wildtieren in Tanzania.