An analgesic comparison of floctafenine (Idarac) and dihydrocodeine in post-operative pain.
A double-blind crossover study comparing floctafenine 200 mg, a new analgesic drug, and dihydrocodeine 60 mg, was performed on 72 patients suffering from post-operative pain. Degree of pain relief by floctafenine was similar to that of dihydrocodeine but the relief afforded by the former was of longer duration. Side-effects associated with dihydrocodeine were statistically higher than those associated with floctafenine. Floctafenine was demonstrated to be an effective analgesic with an insignificant incidence of untoward side-effects.
D000328:Adult; D000368:Aged; D000700:Analgesics / Q000627:therapeutic use; D003061:Codeine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D062367:ortho-Aminobenzoates / Q000009:adverse effects / Q000627:therapeutic use*
D000700:Analgesics; D062367:ortho-Aminobenzoates; C014481:dihydrocodeine; D003061:Codeine