title: Significance of cellular interactions in the immune response.
abstract: Recent investigations relevant to T and B cell cooperation in humoral immunity are discussed from the following aspects: requirement for T cells in antibody responses; T cell facilitation of B cell responsiveness; T cell suppression of B cell responsiveness; evidence for a nonspecific influence of T cells on B cell responsiveness; relevance to clinical disorders.
mesh_terms: D000818:Animals; D000917:Antibody Formation; D000941:Antigens; D000951:Antigens, Neoplasm; D001327:Autoimmune Diseases / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology*; D001666:Binding Sites, Antibody; D001667:Binding, Competitive; D004140:Dinitrophenols; D004342:Drug Hypersensitivity / Q000276:immunology; D000939:Epitopes; D004912:Erythrocytes / Q000276:immunology; D006433:Hemocyanins; D006736:Horses / Q000276:immunology; D007108:Immune Tolerance; D007111:Immunity, Cellular; D007116:Immunization, Passive; D007075:Immunoglobulin M; D007156:Immunologic Memory; D007165:Immunosuppression Therapy; D008264:Macrophages / Q000276:immunology; D051379:Mice; D011135:Polysaccharides, Bacterial; D012756:Sheep / Q000276:immunology; D013291:Streptococcus / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland / Q000002:abnormalities
chemical_list: D000941:Antigens; D000951:Antigens, Neoplasm; D004140:Dinitrophenols; D000939:Epitopes; D007075:Immunoglobulin M; D011135:Polysaccharides, Bacterial; D006433:Hemocyanins