25-Hydroxycholecaliferol and fractures of the proximal.
Plasma 25-hydroxycholecalciferol (25-H.C.C.) has been measured in 67 consective cases of fracture of the proximal femur. The values found in these patients were not different from values found in these patients were not different from those in control groups at the same time of the year. Plasma 25-H.C.C. was not correlated to plasma calcium or phosphorus, the Ca times P product, or the alkaline phosphatase. X-rays showed Looser zones in only 1 patient, in whom the lowest plasma 25-H.C.C. was found. Osteomalacia is not uncommon among elderly people in Denmark, but it is more likely to depend on a decline in the renal efficiency to convert 25-H.C.C. to 1,25-dihydroxycholecalciferol than a low dietary intake of vitamin D.
D000328:Adult; D000367:Age Factors; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood; D002118:Calcium / Q000097:blood; D002986:Clinical Trials as Topic; D003718:Denmark; D005264:Femoral Fractures / Q000097:blood* / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood* / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008875:Middle Aged; D010018:Osteomalacia / Q000097:blood / Q000150:complications / Q000209:etiology; D010758:Phosphorus / Q000097:blood; D012621:Seasons; D006113:United Kingdom; D014807:Vitamin D / Q000008:administration & dosage
D006887:Hydroxycholecalciferols; D014807:Vitamin D; D010758:Phosphorus; D000469:Alkaline Phosphatase; D002118:Calcium