Formation and inactivation of a chemically reactive metabolite of vinyl chloride.
D000818:Animals; D003545:Cysteine / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003634:DDT / Q000494:pharmacology; D004851:Epoxide Hydrolases / Q000502:physiology; D004852:Epoxy Compounds / Q000494:pharmacology; D005978:Glutathione / Q000494:pharmacology; D006843:Hydrocarbons, Chlorinated / Q000494:pharmacology; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism*; D009249:NADP / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology; D011335:Proadifen / Q000494:pharmacology; D011485:Protein Binding; D051381:Rats; D014752:Vinyl Chloride / Q000378:metabolism*; D014753:Vinyl Compounds / Q000378:metabolism*
D004852:Epoxy Compounds; D006843:Hydrocarbons, Chlorinated; D014753:Vinyl Compounds; D009249:NADP; D003577:Cytochrome P-450 Enzyme System; D011335:Proadifen; D003634:DDT; D004851:Epoxide Hydrolases; D005978:Glutathione; D003545:Cysteine; D014752:Vinyl Chloride; D010634:Phenobarbital