[Nitroglycerin and amyl nitrite action on common bile duct during operation for vesicular lithiasis (author's transl)].
Eight patients undergoing cholecystectomy received a single injection of nitroglycerin (0,9 mg) and 8 received amyl nitrite, during a cholangio-kinesimetry. The maximum fall in common bile duct pressure was similar in both group; 3.2 +/- 0.3 torr after nitroglycerin (NTG),3.8 +/- 0.6 torr after amyl nitrite (AN). NTG caused a more persistent lowering of pressure than AN; 614 +/- 42 seconds/343 +/- 27 seconds (p < 0.001). This study showed that it is possible to produce a relaxation of biliary tract muscle fibres with an injection of nitroglycerin and then replace amyl nitrite during anesthesia.
D000328:Adult; D000368:Aged; D000680:Amyl Nitrite / Q000494:pharmacology*; D002769:Cholelithiasis / Q000601:surgery*; D003135:Common Bile Duct / Q000187:drug effects* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000494:pharmacology*; D011312:Pressure
D000680:Amyl Nitrite; D005996:Nitroglycerin
Effects des dérivés nitrés sur le tonus des voies biliaires au cours de la chirurgie de la lithiase vésiculaire.