Cobalt-labeled bleomycin--a new radiopharmaceutical for tumor localization. A comparative clinical evaluation with gallium citrate.
The efficacy of 57Co-labeled bleomycin as a tumor-scanning agent was evaluated in 50 patients with malignant tumor. In terms of sensitivity, labeled bleomycin was found to be a superior agent for malignant tumor detection when compared with 67Ga-citrate (p less than or equal to 0.005). Maximum sensitivity (96%) was found in epidermoid carcinomas. Because of rapid blood clearance and rapid excretion by the kidneys, interpretation of 57Co-bleomycin scans is facilitated.
D000230:Adenocarcinoma / Q000175:diagnosis; D001761:Bleomycin; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D003037:Cobalt Radioisotopes; D005260:Female; D005708:Gallium; D006801:Humans; D008545:Melanoma / Q000175:diagnosis; D008875:Middle Aged; D009369:Neoplasms / Q000175:diagnosis*
D003037:Cobalt Radioisotopes; D001761:Bleomycin; D005708:Gallium