title: [Functional respiratory and blood gas analytical studies of the effects of fenspiride, in oral and intramuscular administration, in chronic bronchopneumopathic subjects].
abstract: A group of 20 chronic bronchopneumopathics was treated for 15 days with fenspiride orally and i.m. The behaviour of a set of functional respiratory and haemogasanalytic parameters was monitored at various times (basic, 5th, 10th and 15th days). Progressive, significant improvements in VC, FEV1, RV and in related parameters were observed. These were attributed to the drug's anti-inflammatory effect in the respiratory ways as well as to its direct antibronchospastic action. Stress is laid on the excellent clinical tolerance of fenspiride following its oral and i.m. administration.
mesh_terms: D000328:Adult; D000368:Aged; D001784:Blood Gas Analysis; D001982:Bronchial Diseases / Q000188:drug therapy*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012119:Respiration / Q000187:drug effects; D012129:Respiratory Function Tests; D013141:Spiro Compounds / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D013141:Spiro Compounds
vernacular_title: Rilievi funzionali respiratori ed emogasanalitici sugli effetti della fenspiride per via orale ed intramuscolare in soggetti broncopneumopatici cronici.