Depression of exploratory activity by clonidine in rats as a model for the detection of relative pre- and postsynaptic central noradrenergic receptor selectivity of alpha-adrenolytic drugs.
D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology*; D000818:Animals; D002490:Central Nervous System / Q000187:drug effects*; D002540:Cerebral Cortex / Q000502:physiology; D003000:Clonidine / Q000494:pharmacology*; D003864:Depression, Chemical; D004558:Electric Stimulation; D005106:Exploratory Behavior / Q000187:drug effects*; D066298:In Vitro Techniques; D008297:Male; D008960:Models, Psychological; D009638:Norepinephrine / Q000502:physiology; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects*; D014649:Vas Deferens / Q000187:drug effects
D000317:Adrenergic alpha-Antagonists; D011941:Receptors, Adrenergic; D003000:Clonidine; D009638:Norepinephrine