title: Chloralose induced alteration of visually evoked response from specific and non-specific regions of cat neocortex.
abstract: Visually evoked response (VER) and EEG from the motor cortex (precruciate gyrus) and the visual cortex (marginal gyrus) of cats were recorded from 4 to 7 h after the injection of anesthetic doses of alpha-chloralose. During the recording period the VER from the precruciat gyrus showed a 200-300% increase in amplitude while the VER from the marginal gyrus rarely varied more than 50% in amplitude, and did so independent of the changes in the VER from the precruciate gyrus. The number of large amplitude spikes in the EEG from the precruciate gyrus also increased dramatically during the recording period, but no definite correlation between changes in VER amplitude and in the number of spikes in the EEG could be demonstrated. These observations suggest a functional separation between specific and nonspecific sensory pathways, with the latter showing a considerably greater sensitivity to level of anesthesia.
mesh_terms: D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000187:drug effects* / Q000502:physiology; D002698:Chloralose / Q000494:pharmacology*; D004569:Electroencephalography; D005071:Evoked Potentials; D009044:Motor Cortex / Q000187:drug effects / Q000502:physiology; D009434:Neural Pathways; D010812:Physical Stimulation; D014785:Vision, Ocular; D014793:Visual Cortex / Q000187:drug effects / Q000502:physiology
chemical_list: D002698:Chloralose