[Double paraneoplastic syndrome and anaplastic carcinoma of the lung. ADH and ACTH levels in the tumoral tissue (author's transl)].
A double paraneoplasic syndrome with hypersecretion of ADH and ACTH revealed the presence of a small cell bronchial cancer in a man aged 62 years. Water and electrolyte anomalies due to the hypersecretions were of such a degree that an occlusive syndrome occurred. Very high levels of ADH and ACTH were found in the tumoral tissue. The measurement of these levels is rarely conducted at the present time but was able to define the mechanism of abnormal secretion of these two hormones in this case.
D001078:APUD Cells / Q000378:metabolism; D000308:Adrenocortical Hyperfunction / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000032:analysis*; D002277:Carcinoma / Q000032:analysis* / Q000150:complications; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000378:metabolism; D008175:Lung Neoplasms / Q000032:analysis* / Q000150:complications; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000150:complications / Q000378:metabolism*; D014667:Vasopressins / Q000032:analysis*; D014883:Water-Electrolyte Imbalance / Q000209:etiology
D014667:Vasopressins; D000324:Adrenocorticotropic Hormone
Double syndrome paranéoplasique au cours d'un carcinome anaplasique du poumon. Dosage de l'ADH et de l'ACTH dans le tissu tumoral.