Influence of dose on first-pass kinetics of 14C-imipramine in the isolated perfused rat liver.
D000818:Animals; D001646:Bile / Q000187:drug effects / Q000378:metabolism; D001711:Biotransformation; D002756:Cholagogues and Choleretics; D003891:Desipramine / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D007099:Imipramine / Q000008:administration & dosage / Q000378:metabolism*; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D008297:Male; D051381:Rats; D013997:Time Factors
D002756:Cholagogues and Choleretics; D007099:Imipramine; D003891:Desipramine