title: Dixyrazine (Esucos) as premedication for esophagogastroscopy. A controlled double-blind trial.
abstract: Dixyrazine (Esucos) as premedication for esophagogastroscopy was studied in a double-blind trial with diazepam and atropine in 321 successive endoscopies. It was established that dixyrazine was fairly well tolerated, regurgitation was significantly reduced. A distinct antiemetic effect was observed compared with diazepam; the difference was statistically significant in the male patients. Dixyrazine may be regarded as a fairly good alternative premedication for esophagogastroscopy.
mesh_terms: D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001285:Atropine / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003975:Diazepam / Q000627:therapeutic use; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D004945:Esophagoscopy / Q000379:methods*; D005260:Female; D005773:Gastroscopy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010640:Phenothiazines / Q000627:therapeutic use*; D011292:Premedication
chemical_list: D014150:Antipsychotic Agents; D010640:Phenothiazines; D001285:Atropine; D003975:Diazepam