"Epi-" and intramedullary neurilemmoma of the spinal cord with denervation atrophy in the related skeletal muscles.
The autopsy of a 68-year-old male who died of cardiac infarction revealed an ep - and intramedullary neurilemmoma of the spinal cord as an associated finding half a year prior to death. The patient had suffered from progressive weakness and sensory disturbances of the lower limbs together with muscular wasting for 6 months. Repeated neurological examinations had led to the diagnosis of an intraspinal space occupation which, however, could not be substantiated by myelography because of its surprisingly small size. The Schwann cell proliferation originated from the adventitia of the epi- and intramedullary vessels of the conus medullaris. The main tumor mass was epi-medullary and extended into the medullary parenchyma via the penetrating vessels forming intramedullary nodules. The special findings in the present case seem to support the hypothesis that intramedullary neurilemmomas originate from the perivascular nerve endings.
D000368:Aged; D001344:Autopsy; D006801:Humans; D007866:Leg; D008297:Male; D009121:Muscle Denervation; D009132:Muscles / Q000473:pathology; D009133:Muscular Atrophy / Q000209:etiology* / Q000473:pathology; D009442:Neurilemmoma / Q000150:complications* / Q000473:pathology; D010543:Peroneal Nerve / Q000473:pathology; D012583:Schwann Cells / Q000473:pathology; D012584:Sciatic Nerve / Q000473:pathology; D013116:Spinal Cord / Q000473:pathology; D013120:Spinal Cord Neoplasms / Q000150:complications* / Q000473:pathology