[Histamine liberation in man following plasma substitution with gelatine and dextran: cause of anaphylactic reactions in the hospital?].
After rapid gelatin infusion in many cases a release of relatively small amounts of histamine was observed. Clinical symptoms occured in 5 cases in correspondence to the increased histamine levels, but were relatively harmless. The application of dextran 60 induced anaphylactoid reactions in 2 persons, with death in one case. Plasma histamine level were normal in both cases. Histamine release probably is not the cause of dextrn induced anaphylactoid reactions.
D000707:Anaphylaxis / Q000139:chemically induced*; D003911:Dextrans / Q000009:adverse effects; D005780:Gelatin / Q000009:adverse effects; D005860:Germany, West; D006636:Histamine Release; D006761:Hospitals; D006801:Humans; D010952:Plasma Substitutes / Q000009:adverse effects*
D003911:Dextrans; D010952:Plasma Substitutes; D005780:Gelatin
Histaminfreisetzung beim Menschen durch Plasmasubstitut auf Gelatine- und Dextranbasis: Ursache der anaphylaktoiden Reaktionen in der Klinik