The influence of pH on the sex-related differences in renal organic ion transport.
The stimulating effects of elevated medium pH and androgen on in vitro transport of p-aminohippurate and N-methylnicotinamide (NMN) were additive, although the androgenic effect was pH-dependent only in the case of NMN. The similarity of response of the 2 systems supports the idea of a common passive efflux pathway for organic anions and cations.
D000618:Aminohippuric Acids / Q000378:metabolism*; D000818:Animals; D000838:Anions; D001692:Biological Transport; D002412:Cations; D005260:Female; D006863:Hydrogen-Ion Concentration; D007672:Kidney Cortex / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D009536:Niacinamide / Q000031:analogs & derivatives* / Q000378:metabolism; D051381:Rats; D012723:Sex; D010130:p-Aminohippuric Acid / Q000378:metabolism*
D000618:Aminohippuric Acids; D000838:Anions; D002412:Cations; D009536:Niacinamide; D010130:p-Aminohippuric Acid