Pancuronium binding by serum proteins.
Pancuronium has not been suspected of binding to serum proteins. Experimental evidence is presented of strong binding to gamma globulin, and of moderate binding to albumin. No evidence could be found of binding to alpha of beta globulin fractions. Less than 13% of a dose in the clinical range would be unbound and active.
D000510:Alpha-Globulins; D001609:Beta-Globulins; D001798:Blood Proteins; D006801:Humans; D010197:Pancuronium / Q000097:blood*; D011485:Protein Binding; D012709:Serum Albumin; D005719:gamma-Globulins
D000510:Alpha-Globulins; D001609:Beta-Globulins; D001798:Blood Proteins; D012709:Serum Albumin; D005719:gamma-Globulins; D010197:Pancuronium