title: The inhibitory effect of bovine rumen fluid on Salmonella typhimurium.
abstract: The possible fate of Salmonella typhimurium in the rumen was investigated by monitoring rumen volatile fatty acids (VFA), lactate concentrations and pH over periods which included regular feeding and 48 h starvation. Preparations were made containing 50 per cent rumen fluid from the cow or VFA solutions, and then inoculated with S typhimurium. Viable counts before and after incubation for 24 h at 37 degrees C were compared. Incubation in broths with high concentrations of VFA and low pH resulted in a marked decrease in salmonella numbers, while lower VFA concentrations had little or no inhibitory effect on growth.
mesh_terms: D000818:Animals; D001826:Body Fluids / Q000502:physiology; D002417:Cattle / Q000378:metabolism*; D005232:Fatty Acids, Volatile / Q000494:pharmacology; D005260:Female; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D012417:Rumen / Q000378:metabolism*; D012486:Salmonella typhimurium / Q000254:growth & development*
chemical_list: D005232:Fatty Acids, Volatile