Treatment of deep-vein thrombosis with intermittent streptokinase and plasminogen infusion.
17 consecutive patients who presented with extensive deep-vein thrombosis, confirmed by phlebography, were included in this study. Of 12 patients who received streptokinase and plasminogen infusion, complete lysis of thrombi was obtained in 8 and partial but extensive lysis in 4. In contrast, thrombi remained unchanged in each of 5 patients who received the same doses of streptokinase infusion only.
D000328:Adult; D000368:Aged; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D010958:Plasminogen / Q000008:administration & dosage* / Q000627:therapeutic use; D013300:Streptokinase / Q000008:administration & dosage* / Q000627:therapeutic use; D013924:Thrombophlebitis / Q000188:drug therapy*; D013997:Time Factors
D010958:Plasminogen; D013300:Streptokinase