[Characteristics of the changes in the intra- and extracellular K+ and Na+ concentrations and the intra- and extracellular pH in the area of cardiac ishemia in experimental myocardial infarct complicated by ventricular fibrillation].
Localized ischemia of the heart complicated by ventricular fibrillation is characterized by a tendency to a higher rate of decrease in intra- and extracellular K+ gradient and intracellular pH in the myocardium as compared to cases without fibrillation. The higher rate of K+ escape from the ischemic cells may be linked with a sharper intracellular oxidation, evidence of which is the correlative dependence between the severity of disorders of K+ balance and decrease in intracellular pH in the myocardium in ischemia.
D000818:Animals; D002414:Cations, Monovalent; D003327:Coronary Disease / Q000378:metabolism*; D004285:Dogs; D005110:Extracellular Space / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007424:Intracellular Fluid / Q000378:metabolism; D009203:Myocardial Infarction / Q000150:complications* / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*; D014693:Ventricular Fibrillation / Q000209:etiology* / Q000378:metabolism
D002414:Cations, Monovalent; D012964:Sodium; D011188:Potassium
Ob osobennostiakh izmeneniĭ vnutri- i vnekletochnykh kontsentratsiĭ K+ i Na+, vnutri- i vnekletochnogo pH v zone ishemii serdtsa pri éksperimental'nom infarkte miokarda, oslozhnennom fibrilliatsieĭ zheludochkov.