The insulin receptor in vertebrates is functionally more conserved during evolution than insulin itself.
D000818:Animals; D001001:Anura; D005075:Biological Evolution; D002645:Chickens; D006168:Guinea Pigs; D006863:Hydrogen-Ion Concentration; D007328:Insulin / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D051379:Mice; D051381:Rats; D011972:Receptor, Insulin / Q000378:metabolism*; D013045:Species Specificity; D013329:Structure-Activity Relationship; D013696:Temperature; D014337:Trout; D014422:Turkeys
D007328:Insulin; D011972:Receptor, Insulin