[Role of B-lymphocytes in inactivating allogenic stem cells].
Antisera to membrane antigens of B lumphocytes eliminated the capacity of lymphocytes to inactivate allogenous stem cells by 60%; however, lymphocytes from the lymph nodes of B mice possessed no inactivating capacity. T-lymphocytes were the main criteria inactivating allogenous stem cells. Cooperating with T-lymphocytes, B-lymphocytes probably contributed to inactivation of precursor cells realized by T-lymphocytes. However, the presence of B-lymphocytes in the killer cells population was not a determinant, since T-lymphocytes were capable of inactivating allogenous stem cells without any participation of B-lymphocytes.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000276:immunology; D007694:Killer Cells, Natural / Q000276:immunology; D051379:Mice; D008808:Mice, Inbred CBA; D008815:Mice, Inbred Strains; D013601:T-Lymphocytes / Q000276:immunology*; D014184:Transplantation, Homologous
Rol' B-limfotsitov v inaktivatsii allogennykh stvolovykh kletok.