Prenatal diagnosis of neural tube defects.
A prospective program for the prenatal detection of neural tube defects in a high-risk pregnancy group has been under way for one year. Twenty high-risk mothers have undergone a complete prenatal work-up, including sonography, amniocentesis, and amniotic fluid and maternal serum alpha-fetoprotein quantitation. Within this group, two cases were prospectively diagnosed and were later confirmed.
D000028:Abortion, Induced; D000328:Adult; D000653:Amniotic Fluid / Q000032:analysis; D000757:Anencephaly / Q000175:diagnosis*; D005260:Female; D005326:Fetal Proteins / Q000032:analysis*; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis*; D008591:Meningomyelocele / Q000175:diagnosis*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011446:Prospective Studies; D012306:Risk; D016135:Spinal Dysraphism / Q000175:diagnosis*; D013997:Time Factors; D000509:alpha-Fetoproteins / Q000032:analysis*
D005326:Fetal Proteins; D000509:alpha-Fetoproteins