Trial of digoxin in mania.
A suggestion that mania is associated with an increased membrane transport of sodium has been investigated in a double-blind trial of a specific Na-K A.T.P.ase inhibitor (digoxin) in twelve female inpatients with mania. Digoxin had no effect.
D001692:Biological Transport; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000378:metabolism; D002986:Clinical Trials as Topic; D004077:Digoxin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010919:Placebos; D012964:Sodium / Q000378:metabolism
D010919:Placebos; D004077:Digoxin; D012964:Sodium