A critical search for evidence of changes in levels of circulating IgE in patients with cancer.
Serum-IgE levels in 95 patients with various advanced malignant conditions were determined by the radioimmunosorbent test. The results obtained did not support the claims of other workers that a high proportion of untreated cancer patients have extremely high circulating IgE levels, attributable to the release of a tumour constituent which interferes with this radioimmunoassay procedure.
D001782:Blood Donors; D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D007070:Immunoglobulin A; D007073:Immunoglobulin E / Q000302:isolation & purification*; D007158:Immunologic Techniques; D007457:Iodine Radioisotopes; D009194:Myeloma Proteins; D009369:Neoplasms / Q000188:drug therapy / Q000276:immunology*; D011863:Radioimmunoassay
D007070:Immunoglobulin A; D007457:Iodine Radioisotopes; D009194:Myeloma Proteins; D007073:Immunoglobulin E; D003520:Cyclophosphamide