Lentiginosis profusa syndrome. IV. Giant pigment granules (light microscopy).
Ionically separated epidermal sheets from pigmentations of two patients with lentiginosis profusa were incubated in dopa (3,4 dihydroxyphenylalanine) and slide-mounted. Light microscopy revealed intracellular giant pigment granules which appeared like those seen with von Recklinghausen's disease.
D000328:Adult; D005260:Female; D006801:Humans; D007911:Lentigo / Q000473:pathology*; D008544:Melanocytes / Q000648:ultrastructure*; D008875:Middle Aged; D012867:Skin / Q000648:ultrastructure*