Comparison of cefamandole nafate to cefamandole by microbiological assay.
Before microbiological assay, cefamandole nafate should be hydrolyzed for 1 h at 37 degrees C in pH 8 buffer (0.1 M) or for 30 min at room temperature in aqueous solutions containing 1.25 molar equivalents of sodium carbonate.
D001419:Bacteria / Q000187:drug effects*; D002254:Carbonates; D002435:Cefamandole / Q000031:analogs & derivatives* / Q000494:pharmacology*; D002511:Cephalosporins / Q000031:analogs & derivatives* / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D008826:Microbial Sensitivity Tests
D002254:Carbonates; D002511:Cephalosporins; D002435:Cefamandole