title: Differential cellular immune responsiveness to systems of the major histocompatibility complex.
abstract: Antigens determined by genes of the major histocompatibility complex can be divided into two systems" the LD (lymphocyte-defined or L determinant) and SD (serologically defined or S determinant) antigens. This division is based on the differential cellular responsiveness to these two sets of antigens of two subpopulations of T lymphocytes: a proliferating helper cell responds primarily to the LD antigens while a cytotoxic T lymphocyte responds most strongly to the SD antigens.
mesh_terms: D000818:Animals; D000917:Antibody Formation; D002874:Chromosome Mapping; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D005796:Genes; D006087:Graft vs Host Reaction; D006649:Histocompatibility Antigens / Q000032:analysis*; D006801:Humans; D007111:Immunity, Cellular; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D009154:Mutation; D051381:Rats
chemical_list: D000939:Epitopes; D006649:Histocompatibility Antigens