Induction of spermatogenesis in the naturally cryptorchid pig.
Abdominal testes of adult, naturally unilaterally cryptorchid boars were subjected to continuous artificial cooling for 5, 15, 25, or 45 days. This treatment initiated development of the spermatogenic epithelium. After a cooling period of 45 days there was complete differentiation in many seminiferous tubules. The results indicate that the spermatogenic arrest in abdominally located testes is not due to an inborn defect in the testis, but is caused by the maintenance of the testis at the abdominal temperature.
D000818:Animals; D001706:Biopsy; D002454:Cell Differentiation; D003456:Cryptorchidism / Q000662:veterinary*; D006801:Humans; D007036:Hypothermia, Induced / Q000662:veterinary; D008297:Male; D013091:Spermatogenesis; D013552:Swine; D013553:Swine Diseases / Q000473:pathology / Q000628:therapy*; D013737:Testis / Q000473:pathology; D013997:Time Factors