Surface markers on human B and T lymphocytes. VIII. Association between complement and Epstein-Barr virus receptors on human lymphoid cells.
An association has been found between the Epstein-Barr virus (EBV) and complement (C3d) receptors on human lymphoid cells. The evidence was four-fold: there was a correlation between the expression of these two receptors; inhibition experiments showed that the binding sites probably are close to each other in the cell membrane, although not identical; EBV and complement receptors have been found to co-cap in either order; and lymphoid cell lines lacking complement receptors could not be superinfected with EBV.
D000956:Antigens, Viral / Q000032:analysis; D001402:B-Lymphocytes / Q000276:immunology*; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology*; D003176:Complement C3 / Q000032:analysis; D003165:Complement System Proteins / Q000032:analysis; D000939:Epitopes; D004912:Erythrocytes / Q000276:immunology; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D007104:Immune Adherence Reaction; D009500:Neutralization Tests; D013601:T-Lymphocytes / Q000276:immunology*
D000956:Antigens, Viral; D003176:Complement C3; D000939:Epitopes; D003165:Complement System Proteins