Biochemical properties of a hamster syncytium-forming ("foamy") virus.
A hamster syncytium-forming ("foamy") virus (HFV) was characterized. The HFV sedimented in isopyknic sucrose density gradients at 1.16-1.165 g/ml. It had RNA but no DNA, its replication was inhibited by actinomycin D, and it contained virion-associated, RNA-dependent DNA polymerase. Analysis of the RNA from purified virus showed several species: 62S, 40S, 28-30S, 18-20S, and 4-7S.
D000818:Animals; D002499:Centrifugation, Density Gradient; D002999:Clone Cells; D006224:Cricetinae / Q000382:microbiology*; D004279:DNA, Viral / Q000378:metabolism; D003609:Dactinomycin / Q000494:pharmacology; D006358:Hot Temperature; D009369:Neoplasms / Q000382:microbiology; D012328:RNA Viruses / Q000378:metabolism*; D012367:RNA, Viral / Q000378:metabolism; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D013539:Simian virus 40 / Q000302:isolation & purification / Q000378:metabolism*; D016092:Spumavirus / Q000302:isolation & purification / Q000378:metabolism*; D014779:Virus Replication / Q000187:drug effects
D004279:DNA, Viral; D012367:RNA, Viral; D003609:Dactinomycin; D012194:RNA-Directed DNA Polymerase