Treatment of radiation-induced gastrointestinal distress with acetylsalicylate.
Highly buffered acetylsalicylate was used to treat diarrhoea and other gastrointestinal side-effects of radiotherapy in 28 women who were receiving treatment for uterine cancer. In a double-blind, balanced, and randomised trial, acetylsalicylate significantly reduced the number of bowel motions and relieved abdominal pain and flatulence.
D000863:Antacids / Q000008:administration & dosage / Q000627:therapeutic use; D001241:Aspirin / Q000008:administration & dosage / Q000627:therapeutic use*; D002021:Buffers; D002986:Clinical Trials as Topic; D003967:Diarrhea / Q000188:drug therapy* / Q000209:etiology; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D009325:Nausea / Q000188:drug therapy* / Q000209:etiology; D011832:Radiation Injuries / Q000188:drug therapy*; D011878:Radiotherapy / Q000009:adverse effects*; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy
D000863:Antacids; D002021:Buffers; D004338:Drug Combinations; D001241:Aspirin