Digitoxin metabolism by rat liver homogenates, subcellular fractions and isolated hepatocytes: stimulation by spironolactone and pregnenolone-16 alpha-carbonitrile.
D000818:Animals; D001711:Biotransformation; D004074:Digitoxin / Q000378:metabolism*; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D009243:NAD / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D011285:Pregnenolone Carbonitrile / Q000494:pharmacology*; D051381:Rats; D013148:Spironolactone / Q000494:pharmacology*; D013347:Subcellular Fractions / Q000187:drug effects / Q000378:metabolism
D009243:NAD; D011285:Pregnenolone Carbonitrile; D013148:Spironolactone; D009249:NADP; D004074:Digitoxin