title: Prolonged inhibition of neurons by neuroendocrine cells in Aplysia.
abstract: In the abdominal ganglion of Aplysia, a burst of action potentials in peptide-secreting neuroendocrine cells, the bag cells, produces slow inhibition of two identified bursting pacemaker neurons. The inhibition is due to slow hyperpolarizing potential that reduces bursting pacemaker activity for 3 hours or more. The slow inhibitory potential results from a large and prolonged increase in membrane conductance to potassium ions as well as a slower ionic process that is relatively independent of membrane conductance.
mesh_terms: D000200:Action Potentials; D000818:Animals; D001048:Aplysia / Q000502:physiology*; D004553:Electric Conductivity; D004558:Electric Stimulation; D005260:Female; D005724:Ganglia / Q000502:physiology; D009433:Neural Inhibition; D009490:Neurosecretory Systems / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000502:physiology; D010058:Oviposition; D010455:Peptides / Q000502:physiology
chemical_list: D018377:Neurotransmitter Agents; D010455:Peptides