17 beta-carboxamide steroids are a new class of glucocorticoid antagonists.
D000818:Animals; D002478:Cells, Cultured; D003907:Dexamethasone / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D004790:Enzyme Induction / Q000187:drug effects; D005938:Glucocorticoids / Q000037:antagonists & inhibitors*; D008114:Liver Neoplasms, Experimental / Q000201:enzymology; D011965:Receptors, Glucocorticoid / Q000378:metabolism; D013329:Structure-Activity Relationship; D014444:Tyrosine Transaminase / Q000096:biosynthesis
D005938:Glucocorticoids; D011965:Receptors, Glucocorticoid; D003907:Dexamethasone; D014444:Tyrosine Transaminase