Direct measurement of the pH in the stomach of the conscious rat, using a special electrode.
The construction and use of a specially designed electrode to measure gastric pH in the conscious rat is described. Measurement of gastric hydrogen ion activity with this device is rapid and reproducible in starved rats. A dose-related increase of gastric pH was obtained after s.c. injection of the anticholinergic isopropamide.
D000818:Animals; D004566:Electrodes; D005750:Gastric Juice / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D008297:Male; D008722:Methods; D051381:Rats