Intravenous tyramine pressor response in depression.
Tyramine-dose/pressor-response curves have been determined in 27 control subjects and 19 patients with primary depressive illness. In the depressive group, significantly lower doses of tyramine were required to elevate the systolic blood-pressure by 30 mm. Hg.
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D003863:Depression / Q000209:etiology / Q000503:physiopathology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000172:deficiency / Q000378:metabolism / Q000502:physiology; D011941:Receptors, Adrenergic; D012737:Sex Factors; D014439:Tyramine / Q000008:administration & dosage / Q000494:pharmacology*
D011941:Receptors, Adrenergic; D009638:Norepinephrine; D014439:Tyramine