Immunofluorescence studies in herpes gestationis.
In 4 cases of H.G., direct junctional immunofluorescence findings showed an intense band of C3 present in the involved skin of the patients even after the active lesions had disappeard (i.e. 2 months later). Weak specific fluorescence for IgG and in one case also for IgA and IgM was seen in the involved skin. A less intense junctional band of C3 was also present in the uninvolved skin. Antibodies against basal membrane have not been detected in the sera of the patients.
D000328:Adult; D000818:Animals; D001485:Basement Membrane / Q000276:immunology; D003165:Complement System Proteins / Q000032:analysis; D003874:Dermatitis Herpetiformis / Q000276:immunology* / Q000473:pathology; D004804:Eosinophils / Q000473:pathology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007106:Immune Sera; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008214:Lymphocytes / Q000473:pathology; D009504:Neutrophils / Q000473:pathology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology* / Q000473:pathology; D011817:Rabbits / Q000276:immunology; D012867:Skin / Q000276:immunology*
D007106:Immune Sera; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D003165:Complement System Proteins