Nitroblue tetrazolium reduction test in pregnancy.
The use of the nitroblue tetrozolium (NRT) dye reduction test as a screening method for bacterial and fungal infections is now widely recognized. Levels have been reported to be falsely elevated in the pregnant state. This report includes a prospective study which showed that the results of this test in 124 pregnant women were indistinguishable from those of a normal control population. Seven of 8 elevated levels were attributable to infection or allergy. With this data, it is concluded that the NBT test can be used to screen for bacterial and fungal illnesses in a febrile pregnant patient as well as in the general population.
D001424:Bacterial Infections / Q000175:diagnosis*; D004396:Coloring Agents; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D009181:Mycoses / Q000175:diagnosis*; D009504:Neutrophils / Q000378:metabolism; D009574:Nitro Compounds; D010084:Oxidation-Reduction; D010587:Phagocytosis / Q000187:drug effects; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D011446:Prospective Studies; D013194:Staining and Labeling; D013778:Tetrazolium Salts
D004396:Coloring Agents; D009574:Nitro Compounds; D013778:Tetrazolium Salts