title: A serial study of pregnancy proteins in primigravidae.
abstract: The plasma concentrations from four 'pregnancy proteins' and three steroid hormones have been measured throughout pregnancy in 15 primigravidae. Two of the proteins, human placental lactogen (HPL) and pregnancy-specific beta1-glycoprotein (PSbetaG), are specific for pregnancy and correlate well with the stage of gestation. It is suggested that measurement of PSbetaG may be useful in assessing feto-placental wellbeing. Neither of the pregnancy-associated proteins, steriod-binding beta-globulin (SBbetaG) and pregnancy-associated alpha2-glycoprotein (alpha2-PAG), correlated with the length of gestation although, near term, plasma alpha2-PAG levels appeared to be related to fetal weight. In addition, no correlation has been demonstrated between placental or fetal weight and any of the pregnancy-specific proteins or steroid hormones studied.
mesh_terms: D000328:Adult; D001609:Beta-Globulins / Q000032:analysis*; D004958:Estradiol / Q000097:blood; D004964:Estriol / Q000097:blood; D005260:Female; D005333:Fetus / Q000502:physiology; D006023:Glycoproteins / Q000097:blood*; D006801:Humans; D010920:Placenta / Q000502:physiology; D010928:Placental Lactogen / Q000097:blood*; D011247:Pregnancy; D011374:Progesterone / Q000097:blood
chemical_list: D001609:Beta-Globulins; D006023:Glycoproteins; D011374:Progesterone; D004958:Estradiol; D010928:Placental Lactogen; D004964:Estriol