Effects of 4-aminopyridine on statistical parameters of transmitter release at the neuromuscular junction.
4-Aminopyridine (4-AP) potentiates transmitter release from motor nerve terminals by increasing the quantum content (m) of endplate potentials. Estimates of the binomial parameters of transmitter release shows that 4-AP enhances m by increasing n and not p.
D000200:Action Potentials / Q000187:drug effects; D000631:Aminopyridines / Q000494:pharmacology*; D000818:Animals; D001001:Anura; D008297:Male; D009469:Neuromuscular Junction / Q000187:drug effects / Q000378:metabolism*; D018377:Neurotransmitter Agents / Q000378:metabolism*; D051381:Rats
D000631:Aminopyridines; D018377:Neurotransmitter Agents