Radioimmunoassay for measuring antibodies specific for group B streptococcal types Ia, Ib, Ic, II, and III.
The object of this study was to develop a test that would measure antibodies directed against group B streptococcal types Ia, Ib, Ic, II, and III. The type-specific carbohydrate antigens were purified, labeled with 125I, and used to develop a radioimmunoassay. This procedure should be particularly useful in testing human sera for group B type-specific antibodies, since it requires very small quantities of antigens and measures primary type antigen-antibody interactions.
D000907:Antibodies, Bacterial / Q000032:analysis*; D000918:Antibody Specificity; D000939:Epitopes; D011863:Radioimmunoassay; D012703:Serotyping; D013292:Streptococcus agalactiae / Q000145:classification / Q000276:immunology*
D000907:Antibodies, Bacterial; D000939:Epitopes