title: Increases in purine excretion and rate of synthesis by drugs inhibiting IMP dehydrogenase or adenylosuccinate synthetase activities.
mesh_terms: D000265:Adenylosuccinate Synthase / Q000037:antagonists & inhibitors*; D000409:Alanine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D002460:Cell Line; D006801:Humans; D007168:IMP Dehydrogenase / Q000037:antagonists & inhibitors*; D007658:Ketone Oxidoreductases / Q000037:antagonists & inhibitors*; D008025:Ligases / Q000037:antagonists & inhibitors*; D008214:Lymphocytes; D009173:Mycophenolic Acid / Q000494:pharmacology; D009602:Nitrosamines / Q000494:pharmacology; D011687:Purines / Q000378:metabolism*; D012265:Ribonucleotides / Q000378:metabolism; D013154:Spleen
chemical_list: D009602:Nitrosamines; D011687:Purines; D012265:Ribonucleotides; C000082:alanosine; D007168:IMP Dehydrogenase; D007658:Ketone Oxidoreductases; D008025:Ligases; D000265:Adenylosuccinate Synthase; D009173:Mycophenolic Acid; D000409:Alanine