[Investigations on the accumulation of radio-bleomycin in gynaecological tumors (author's transl)].
The indication for treatment with Bleomycin in gynaecological tumors is as yet not well defined. At present Bleomycin is primarily used for advanced gynaecological malignancies. Results of our investigations show that the individual affinity of gynaecological tumors to Bleomycin is very variable. In subsequent investigations it should therefore be determined whether the accumulation of radio-Bleomycin and the sensitivity of a gynaecological malignant tumor to Bleomycin therapy show a positive correlation. The probable chances of success of a course of chemotherapy with Bleomycin could then be predicted.
D002288:Adenocarcinoma, Mucinous / Q000378:metabolism; D000232:Adenofibroma / Q000378:metabolism; D000328:Adult; D000368:Aged; D001761:Bleomycin / Q000378:metabolism / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000378:metabolism; D002277:Carcinoma / Q000378:metabolism; D002294:Carcinoma, Squamous Cell / Q000378:metabolism; D003037:Cobalt Radioisotopes; D005260:Female; D005350:Fibroma / Q000378:metabolism; D005833:Genital Neoplasms, Female / Q000175:diagnosis / Q000532:radiotherapy*; D006801:Humans; D007275:Injections, Intravenous; D008875:Middle Aged; D011877:Radionuclide Imaging; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000378:metabolism; D014625:Vaginal Neoplasms / Q000378:metabolism
D003037:Cobalt Radioisotopes; D001761:Bleomycin
Untersuchungen zur Anreicherung von Radio-Bleomycin in gynäkologischen Tumoren