[Cell-mediated immunity after blocking of the H2 lymphocyte receptors].
The effects of cimetidine have been evaluated in 10 normal subjects on cutaneous delayed reactions in vivo, and on E rosette forming cells in vitro, in order to define the significance of the lymphocytes H2 receptors in cell-mediated immunity. The results show the immuno-suppressive activity of histamine, but do not allow us to hypothesize an immuno-regulatory action of cimetidine.
D000328:Adult; D002927:Cimetidine / Q000494:pharmacology; D006632:Histamine / Q000494:pharmacology; D006635:Histamine H2 Antagonists / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D008214:Lymphocytes / Q000276:immunology*; D013299:Streptodornase and Streptokinase / Q000276:immunology
D006635:Histamine H2 Antagonists; D002927:Cimetidine; D006632:Histamine; D013299:Streptodornase and Streptokinase
Studio dell'immunita' cellulo-mediata dopo blocco dei recettori H2 dei linfociti.