[Development of C cells of the thyroid gland of the rat under an antithyroidian treatment inducing gamma tumors].
In the normal ageing rat is observed a progressive hyperplasia of the C cells. In the rat treated by an antithyroideal drug, the hyperplasia is much more important than in normal. It already appears during the treatment and grows up after its stop. This observation means that the C cells hyperplasia, which reaches later to gamma tumors production, is not due to the TSH oversecreted under the antithyroideal drug influence.
D000367:Age Factors; D000818:Animals; D013956:Antithyroid Agents / Q000494:pharmacology*; D006965:Hyperplasia / Q000139:chemically induced / Q000473:pathology; D051381:Rats; D013964:Thyroid Neoplasms / Q000139:chemically induced* / Q000473:pathology; D013972:Thyrotropin / Q000494:pharmacology
D013956:Antithyroid Agents; D013972:Thyrotropin
Evolution des cellules C de la thyroïde du rat soumis à un traitment antithyroïdien générateur de tumeur