The isolation of carbon dioxide-requiring (carboxyphillic) type 19 pneumococcus (Streptococcus pneumoniae) from diseased guinea-pigs.
Type 19 pneumococcus was isolated only in anaerobic cultures from tissue fluids of guinea-pigs suffering from exudative pericarditis and pleuropneumonia. The organism was pathogenic to mice even after 40 subcultures. Further study showed it to be carboxyphilic rather than anaerobic. The necessity of specifying various atmospheric conditions in the diagnostic bacteriological isolation routine is emphasized.
D000818:Animals; D002245:Carbon Dioxide / Q000378:metabolism*; D006168:Guinea Pigs; D010493:Pericarditis / Q000382:microbiology / Q000662:veterinary; D011001:Pleuropneumonia / Q000382:microbiology / Q000662:veterinary; D011008:Pneumococcal Infections / Q000382:microbiology / Q000662:veterinary*; D012376:Rodent Diseases / Q000382:microbiology*; D013296:Streptococcus pneumoniae / Q000302:isolation & purification* / Q000378:metabolism
D002245:Carbon Dioxide