[Change in the lactotropic function of the adenohypophysis and the system of its regulation in rats after thyroidectomy].
The prolaction content in the adenohypophysis decreased more than two-fold, and its biosynthesis and release were significantly intensified in deficiency of thyroid hormones. The study of the hypothalamus and epiphysis links controlling the lactotropic function of the hypophysis demonstrated that the biosynthesis and release of prolactin were not inhibited after thyroidectomy. On the 13th--14th postoperative day no irreversible changes were revealed in the hypothalamic links of the control of this function, since it responded to prolactin administration to the experimental animals.
D000818:Animals; D002369:Castration; D005260:Female; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology*; D007037:Hypothyroidism / Q000503:physiopathology; D018377:Neurotransmitter Agents / Q000502:physiology; D010903:Pituitary Gland, Anterior / Q000378:metabolism*; D011388:Prolactin / Q000096:biosynthesis / Q000378:metabolism*; D051381:Rats; D013965:Thyroidectomy
D018377:Neurotransmitter Agents; D011388:Prolactin
Izmenenie laktotropnoĭ funktsii adenogipofiza i sistem ee reguliatsii u krys posle tireoidektomii.