title: [Evaluation of methisoprinol+ in the treatment of infectious hepatitis. Negative results].
abstract: The usefulness of metisoprinol was evaluated by a double blind study and at random in the treatment of mild infectious hepatitis in a group of 42 children. Twenty-one patients were given the drug at the dose of 50 mg/kg/day, divided t.i.d., by mouth and for 12 days. The other twenty-one patients made up the control group and were given placebo. No modifications nor clinical differences were found in the parameters evaluated; laboratory results were also negative in the studies carried out that might be attributed to the administration of the drug.
mesh_terms: D000284:Administration, Oral; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D006506:Hepatitis A / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007288:Inosine / Q000031:analogs & derivatives*; D007542:Inosine Pranobex / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D010919:Placebos
chemical_list: D010919:Placebos; D007288:Inosine; D007542:Inosine Pranobex
vernacular_title: Evaluación de metisoprinol+ en el tratamiento de la hepatitis infecciosa. Resultados negativos