title: [Effect of cultivation conditions on lipase biosynthesis by Serratia marcescens].
abstract: The effect of cultivation conditions (the composition of the growth medium, pH, temperature) on lipase biosynthesis was studied with Serratia marcescens 345 and Serratia marcescens 348. The composition of the medium was found to be of key importance for lipase synthesis; the highest lipolytic activity of S. marcescens 345 was detected on the medium with 5% soybean flour broth while that of S. marcescens 348 was displayed on MPB. Sodium salts of cholic acids added at different concentrations to the growth medium had different effect on the biosynthesis of exo- and endolipases by the two strains.
mesh_terms: D001647:Bile Acids and Salts / Q000494:pharmacology*; D002793:Cholic Acids / Q000494:pharmacology; D003470:Culture Media; D006000:Glycocholic Acid / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D008049:Lipase / Q000096:biosynthesis*; D012706:Serratia marcescens / Q000201:enzymology* / Q000254:growth & development; D013045:Species Specificity; D013656:Taurocholic Acid / Q000494:pharmacology; D013696:Temperature; D013997:Time Factors
chemical_list: D001647:Bile Acids and Salts; D002793:Cholic Acids; D003470:Culture Media; D013656:Taurocholic Acid; D008049:Lipase; D006000:Glycocholic Acid
vernacular_title: Vliianie usloviia kul'tivirovaniia na biosintez lipazy u Serratia marcescens.