Herpes simplex virus type 1 replication in a gingival cell line.
Propagation of herpes simplex virus type 1 (HSV-1) in gingival cells is advantageous since these cells are more definitive than HeLa cells in demonstrating viral-induced cytopathic effects and are easily and economically maintained in the laboratory. They also provide a potential medium for studying oral tissue reactions to HSV-1 infection. HSV-1-induced cytopathic effects are clearly characterized following inoculation with virus from standard laboratory cultures and human infections.
D002460:Cell Line; D002467:Cell Nucleus / Q000648:ultrastructure; D002843:Chromatin; D002875:Chromosomes; D003593:Cytoplasm / Q000648:ultrastructure; D003896:Desmosomes / Q000648:ultrastructure; D005881:Gingiva / Q000166:cytology / Q000648:ultrastructure; D006801:Humans; D008938:Mitosis; D018139:Simplexvirus / Q000302:isolation & purification / Q000502:physiology*; D013194:Staining and Labeling; D014617:Vacuoles / Q000648:ultrastructure; D014776:Virus Cultivation; D014779:Virus Replication
D002843:Chromatin