Influences of oyster or clam feeding on lipid metabolism in rats.
Rats were fed on three kinds of diets for two weeks: (I) basal diet, (II) containing 0.1% cholate and (III) containing 0.1% cholesterol and 0.1% cholate. Each dietary group was further divided into subgroups to whose diet was added 0, 5 or 10% (dry weight) of minced oyster (Callocorchina) or clam (Tapes japonica). The serum and liver cholesterol levels of the rats fed the basal diet were reduced by feeding oyster or clam. The serum and liver triglyceride levels of all dietary groups were lowered markedly by feeding oyster or clam. The activities of glucose-6-phosphate dehydrogenase, malic enzyme and acetyl-CoA carboxylase were markedly reduced in the basal groups fed oyster or clam. These effects were observed in 5 and 10% shellfish feeding. These shellfish may be considered hypolipidemic foods.
D000103:Acetyl-CoA Carboxylase / Q000378:metabolism; D000818:Animals; D049872:Bivalvia; D002784:Cholesterol / Q000097:blood; D002791:Cholesterol, Dietary / Q000494:pharmacology; D002793:Cholic Acids / Q000494:pharmacology; D002849:Chromatography, Gas; D004041:Dietary Fats; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D008291:Malate Dehydrogenase / Q000378:metabolism; D008297:Male; D010125:Ostreidae; D051381:Rats; D013261:Sterols / Q000032:analysis; D014280:Triglycerides / Q000097:blood
D002791:Cholesterol, Dietary; D002793:Cholic Acids; D004041:Dietary Fats; D013261:Sterols; D014280:Triglycerides; D002784:Cholesterol; D008291:Malate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D000103:Acetyl-CoA Carboxylase