The effect of a second laminated gelatin film on the release rate of sulfadiazine from gelatin-gel matrix.
The influence of a second laminated gelatin film without the drug over a gelatin-gel matrix containing sulfadiazine on the release rate was investigated. It was found that increasing the thickness of the second laminated layer markedly decreased the release of the drug incorporated in the gelatin layer.
D002626:Chemistry, Pharmaceutical; D003692:Delayed-Action Preparations; D004058:Diffusion; D005780:Gelatin; D006863:Hydrogen-Ion Concentration; D013411:Sulfadiazine
D003692:Delayed-Action Preparations; D013411:Sulfadiazine; D005780:Gelatin