Double-blind clinical trial of anaesthetic premedication for use in major day surgery.
Three anaesthetic premedication regimens have been compared by double-blind controlled trial in 158 patients undergoing day-case surgery for varicose veins or hernia. Atropine plus droperidol was superior to atropine plus diazepam or atropine alone in lessening nausea and vomiting and in reducing the need for postoperative analgesia.
D000328:Adult; D000769:Anesthesia, Inhalation; D001285:Atropine / Q000009:adverse effects / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D003631:Day Care, Medical; D003975:Diazepam / Q000009:adverse effects / Q000494:pharmacology*; D004329:Droperidol / Q000009:adverse effects / Q000494:pharmacology*; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006261:Headache / Q000139:chemically induced; D059685:Herniorrhaphy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced; D010149:Postoperative Pain / Q000453:epidemiology; D011229:Preanesthetic Medication; D014648:Varicose Veins / Q000601:surgery; D014839:Vomiting / Q000139:chemically induced
D004338:Drug Combinations; D001285:Atropine; D004329:Droperidol; D003975:Diazepam