New method of diagnosing neurogenic dysfunction of bladder in candidates for urinary undiversion. Denervation supersensitivity of urethra to alpha-agonist.
Testing for denervation supersensitivity response of the urethra to alpha-agonist as a means of excluding neurogenic vesical dysfunction prior to planning undiversion is discussed in a case report. The method is specifically applicable to the bladder that has shrunk from disuse or fibrosis and therefore is not amenable to conventional bladder function studies.
D000316:Adrenergic alpha-Agonists; D002648:Child; D003714:Denervation; D005039:Etilefrine; D005260:Female; D006801:Humans; D008297:Male; D011312:Pressure; D014521:Urethra / Q000503:physiopathology*; D001750:Urinary Bladder, Neurogenic / Q000175:diagnosis*; D014547:Urinary Diversion
D000316:Adrenergic alpha-Agonists; D005039:Etilefrine