[Characteristics of a rat liver cellular extract protein which mediates transport of various phospholipids from liposomes to mitochondria].
The effect of pH, Ca++ and Na+ concentration on the phosphatidylethanolamine transport from liposomes to mitochondria by an aspecific soluble rat liver protein has been studied. Results obtained indicate that at pH higher than 6.5 and Ca++ ion concentrations from 5 mM on the transport is strongly inhibited. Preliminary data with ESR spectrometry concerning the nature of lipoprotein association between phosphatidylethanolamine and carrier protein during the transport are also presented.
D000818:Animals; D002118:Calcium / Q000494:pharmacology; D002352:Carrier Proteins / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy; D006863:Hydrogen-Ion Concentration; D008081:Liposomes / Q000378:metabolism*; D008110:Liver Extracts / Q000494:pharmacology*; D008565:Membrane Proteins; D008930:Mitochondria, Liver / Q000378:metabolism*; D010714:Phosphatidylethanolamines / Q000378:metabolism*; D049294:Phospholipid Transfer Proteins; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats; D012964:Sodium / Q000494:pharmacology
D002352:Carrier Proteins; D008081:Liposomes; D008110:Liver Extracts; D008565:Membrane Proteins; D010714:Phosphatidylethanolamines; D049294:Phospholipid Transfer Proteins; D010743:Phospholipids; D012964:Sodium; D002118:Calcium
Caratteristiche di una proteina del succo cellulare di fegato di ratto me diatrice del trasporto di vari fosfolipidi dai liposomi ai mitocondri.