Telemetered EEG-EOG during psychotic behaviors of schizophrenia.
In an effort to establish correlations between abnormal behaviors characteristic of schizophrenia and simultaneous cerebral electrical activity, EEGs and electro-oculograms (EOGs) were continuously recorded for 2 to 24 hours by radiotelemetry from 40 patients with schizophrenia and 12 normal control subjects. Trained observers recorded specific behavior patterns permitting visual and computer analysis of EEG during hallucinations, stereotypy, catatonia, psychomotor blocking, and other characteristic manifestations of schizophrenia. Electroencephalographic abnormalities consisting of focal slow or spike activity over either temporal region were found in nearly half of the patients so recorded. In contrast to the EEG during ictal episodes of epilepsy, the abnormal wave forms of schizophrenic patients seldom coincided with episodes of blocking, stereotypy, or other abnormal behaviors. Increased extraocular activity or blinking were recorded in a majority of patients, but were not consistently associated with the abnormal behavior or perceptual events.
D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001332:Automatism / Q000503:physiopathology; D004569:Electroencephalography; D004576:Electromyography; D004585:Electrooculography; D004827:Epilepsy / Q000503:physiopathology; D005071:Evoked Potentials / Q000187:drug effects; D005260:Female; D006212:Hallucinations / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010296:Parietal Lobe / Q000503:physiopathology; D011596:Psychomotor Disorders / Q000503:physiopathology; D012438:Saccades / Q000187:drug effects; D012559:Schizophrenia / Q000503:physiopathology*; D012563:Schizophrenia, Paranoid / Q000503:physiopathology; D012564:Schizophrenic Language; D012565:Schizophrenic Psychology; D013239:Stereotyped Behavior / Q000502:physiology; D013686:Telemetry / Q000379:methods*; D013702:Temporal Lobe / Q000503:physiopathology
D014150:Antipsychotic Agents