Dermal toxicity and penetration studies following topical application of three histamine H2-receptor antagonists with a comparison with an H1-receptor antagonist.
D000818:Animals; D003877:Dermatitis, Contact / Q000473:pathology; D005123:Eye / Q000187:drug effects; D006634:Histamine H1 Antagonists / Q000378:metabolism / Q000633:toxicity*; D006635:Histamine H2 Antagonists / Q000378:metabolism / Q000633:toxicity*; D007509:Irritants; D008297:Male; D011817:Rabbits; D012867:Skin / Q000187:drug effects*; D012869:Skin Absorption; D012995:Solubility; D013997:Time Factors
D006634:Histamine H1 Antagonists; D006635:Histamine H2 Antagonists; D007509:Irritants