title: Adverse effects in maintenance treatment: practical and theoretical considerations.
abstract: 1. Subsequent to the introduction of therapeutically effective psychotropic drugs, there has been a decrease in the resident population in mental hospitals. 2. Since maintenance therapy with neuroleptics and lithium may alleviate and/or prevent relapse in a considerable percentage of schizophrenic and manic depressive patients, there is a gradual increase of these patients in the community. 3. In this paper some of the adverse effects of long-term pharmacotherapy with psychotropic drugs will be presented, and possible negative effects of the increase in fertile marriages among community-based patients will be discussed.
mesh_terms: D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D002908:Chronic Disease; D006801:Humans; D008094:Lithium / Q000009:adverse effects / Q000627:therapeutic use; D001523:Mental Disorders / Q000150:complications* / Q000188:drug therapy; D010045:Outpatients; D011619:Psychotropic Drugs / Q000009:adverse effects* / Q000627:therapeutic use; D013723:Teratogens
chemical_list: D000929:Antidepressive Agents, Tricyclic; D014150:Antipsychotic Agents; D011619:Psychotropic Drugs; D013723:Teratogens; D008094:Lithium