Immunologic differentiation of proteins in the surfactant system of the lung.
Immunoelectrophoresis revealed the following four protein components in the lung surfactant system of guinea-pigs: albumin, transferrin, IgG, and an organ-specific protein migrating in the beta-globulin range. These proteins probably take part in the formation of the hypophase of the alveolar lining layer and thereby influence the surface properties of the alveolar air-liquid interface.
D000418:Albumins / Q000032:analysis*; D000818:Animals; D001609:Beta-Globulins / Q000032:analysis*; D006168:Guinea Pigs; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000032:analysis*; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D009206:Myocardium / Q000032:analysis; D011663:Pulmonary Surfactants / Q000032:analysis*; D013154:Spleen / Q000032:analysis; D014168:Transferrin / Q000032:analysis*
D000418:Albumins; D001609:Beta-Globulins; D007074:Immunoglobulin G; D011663:Pulmonary Surfactants; D014168:Transferrin