[Pneumococcal serotyping. Multicentric inventory in hospital. Years 1977-1978 (author's transl)].
For a period of 17 months, 670 pneumococci, mostly isolated in the Paris area, have been typed with contercurrent-immunoelectrophoresis ; 338 of them come from cases of pneumonia, bacteremia, meningitis and acute otitis media. An important regrouping of the most frequent serotypes among the 83 known serotypes makes possible a vaccinal prophylaxis. The tetradecavalent vaccine which is now for sale in USA gives, in the four main pathologies of this enquiry, a coverage superior to 80 percent. Choosing the 14 most frequent serotypes of the four main pathologies of their data the authors propose the following vaccinal formula : 1, 3, 4, 5, 6, 7, 8, 10, 12, 14, 15, 18, 19, 23.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001428:Bacterial Vaccines; D002648:Child; D002675:Child, Preschool; D003378:Counterimmunoelectrophoresis; D005602:France; D006801:Humans; D007167:Immunotherapy; D007223:Infant; D007231:Infant, Newborn; D008586:Meningitis, Pneumococcal / Q000382:microbiology; D008875:Middle Aged; D010033:Otitis Media / Q000382:microbiology; D011014:Pneumonia / Q000382:microbiology; D011135:Polysaccharides, Bacterial; D018805:Sepsis / Q000382:microbiology; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000276:immunology
D001428:Bacterial Vaccines; D011135:Polysaccharides, Bacterial
Sérotypie pneumococcique. Inventaire multicentrique en milieu hospitalier (années 1977-1978).