[Use of various immunological methods for the detection of specific antigen in leukocytes of leukemic patients].
A specific antigen was found in white blood cells of patients with leukemia by means of the indirect immunofluorescence and ring precipitation tests. Using a mixture of hyperimmune rabbit sera with leukocytes from patients with various forms of leukemia (lympholeukemia, myeloleukemia, hemocytoblastosis and reticulosis), it can be found in cells of patients with some forms of this disease. An increased amount of the antigen in the cells was found in cases of myeloleukemia or hemocytoblastosis. The immunofluorescence test was found to be more clear-cut when the time between bleeding and microscopy of preparations was short.
D000951:Antigens, Neoplasm / Q000032:analysis*; D000939:Epitopes; D005455:Fluorescent Antibody Technique; D006801:Humans; D007938:Leukemia / Q000276:immunology*; D007962:Leukocytes / Q000276:immunology*; D011233:Precipitin Tests
D000951:Antigens, Neoplasm; D000939:Epitopes
Primenenie nekotorykh immunologicheskikh metodov dlia vyiavleniia spetsificheskogo antigena b leikotsitakh bol'nykh leikozom