title: Are antihistamines sedative via a blockade of brain H1 receptors?
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D006168:Guinea Pigs; D006634:Histamine H1 Antagonists / Q000494:pharmacology*; D006993:Hypnotics and Sedatives; D007700:Kinetics; D008297:Male; D011738:Pyrilamine / Q000378:metabolism / Q000494:pharmacology; D051381:Rats; D011968:Receptors, Histamine / Q000187:drug effects*; D011969:Receptors, Histamine H1 / Q000187:drug effects* / Q000378:metabolism
chemical_list: D006634:Histamine H1 Antagonists; D006993:Hypnotics and Sedatives; D011968:Receptors, Histamine; D011969:Receptors, Histamine H1; D011738:Pyrilamine