Superinduction of tyrosine aminotransferase in RLC-cells.
Actinomycin D, administered to RLC cells which were pretreated with the glucocorticoid dexamethasone phosphate, causes superinduction of tyrosine aminotransferase. By the addition of actidione it could be proved that the superinduction takes place because of the decreased activity of the tyrosine aminotransferase-degrading enzymes.
D002478:Cells, Cultured; D003513:Cycloheximide / Q000494:pharmacology; D003609:Dactinomycin / Q000494:pharmacology; D003839:Deoxyadenosines / Q000494:pharmacology; D003907:Dexamethasone / Q000494:pharmacology; D004790:Enzyme Induction / Q000187:drug effects; D014444:Tyrosine Transaminase / Q000096:biosynthesis* / Q000378:metabolism
D003839:Deoxyadenosines; D003609:Dactinomycin; D003907:Dexamethasone; D003513:Cycloheximide; D014444:Tyrosine Transaminase