title: Evaluation of topical application of ronnel solution for generalized demodicosis in dogs.
abstract: Of 20 dogs with generalized demodicosis, 18 responded favorably to treatment with 8.5% ronnel solution applied to one-third of the body every 3rd day, in rotation. Duration of treatment was from 5 to 20 weeks. In 2 dogs, the demodicosis recurred and required additional treatment with ronnel. Two dogs died during the study. One death was attributed to ronnel toxicosis; the other was unexplained. Eight of 10 control dogs treated orally and topically for pyoderma associated with demodicosis still had demodicosis 1 year after initiation of the study.
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D004283:Dog Diseases / Q000139:chemically induced / Q000188:drug therapy*; D004285:Dogs; D005260:Female; D008297:Male; D008924:Mite Infestations / Q000188:drug therapy / Q000662:veterinary*; D009946:Organothiophosphorus Compounds / Q000009:adverse effects / Q000627:therapeutic use*; D011711:Pyoderma / Q000188:drug therapy / Q000662:veterinary; D012075:Remission, Spontaneous
chemical_list: D009946:Organothiophosphorus Compounds