[Vascular hyalinosis in diabetic microangiopathy].
A histochemical and immunoluminescent investigation of hyalin of arterioles ans small arteries of the kidney, spleen, pancreas and skin were carried out. In 20 patients with diabetes mellitus of a various degree of gravity and duration hyalinosis represented a manifestation of microangiopathy; it was particularly pronounced in the vessels of the spleen and kidney, and in a lesser degree--in the vessels of the pancreas and skin. The intensity of hyalinosis was directly proportional to the duration of the disease; Immunomorphologically, hyaline masses devealed globulins, gamma M-, gamma G-immunoglobulins, complement, albumins, beta-lipoproteins, fibrinogens, which indicates to a hematogenic nature of the vascular hyalin. The presence in hyalin of G an M-immunoglobulins and complement may testify to the participation in its formation of immune mechanisms, together with metabolic ones.
D000328:Adult; D000368:Aged; D001798:Blood Proteins / Q000032:analysis; D001808:Blood Vessels / Q000473:pathology*; D003925:Diabetic Angiopathies / Q000097:blood / Q000276:immunology / Q000473:pathology*; D006651:Histocytochemistry; D006801:Humans; D006818:Hyalin; D007668:Kidney / Q000098:blood supply; D008875:Middle Aged; D010179:Pancreas / Q000098:blood supply; D012867:Skin / Q000098:blood supply; D013154:Spleen / Q000098:blood supply
D001798:Blood Proteins
O gialinoze sosudov pri diabeticheskoĭ mikroangiopatii