title: [Acute renal insufficiency caused by phenyl-indane-dione. Apropos of 1 case].
abstract: One case of Phenindione (PID) adverse reaction is reported. The patient showed a typical picture of immunological reaction to the drug. In spite of severe bacteremia, she recovered. Only 33 cases of PID intolerance are reported in the literature. In all these patients, renal failure occurred. Superinfection is the most frequent cause of death. PID adverse reaction should be evoqued in the presence of signs such a fever, asthenia, anorexia and cutaneous reaction. The PID should be stopped immediatly but renal failure yet develops. During a PID treatment, frequent evaluation of blood azotemia, creatinine and proteinuria should be performed.
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000150:complications / Q000628:therapy; D004342:Drug Hypersensitivity; D005260:Female; D006801:Humans; D008875:Middle Aged; D010630:Phenindione / Q000009:adverse effects*; D006435:Renal Dialysis; D018805:Sepsis / Q000150:complications; D013203:Staphylococcal Infections / Q000150:complications
chemical_list: D010630:Phenindione
vernacular_title: Insuffisance rénale aiguë à la phényl-indane-dione. A propos d'un cas.