Rapid detection of ringed sideroblasts in erythremic myelosis.
When normoblasts from patients with chronic erythremic myelosis were stained with the anthraquinone dye, alizarine red S, a purple perinuclear halo appeared. This halo corresponded in location to siderotic granules stained with a conventional iron stain. The rapidity of the alizarine red S stain makes it potentially useful for the detection of pathological sideroblasts in certain refractory anemias.
D001853:Bone Marrow / Q000473:pathology*; D001854:Bone Marrow Cells; D003594:Cytoplasmic Granules; D004913:Erythrocytes, Abnormal; D006801:Humans; D007501:Iron / Q000032:analysis*; D004915:Leukemia, Erythroblastic, Acute / Q000175:diagnosis*; D013194:Staining and Labeling / Q000379:methods*
D007501:Iron