title: The hapten-carrier effect in teleost fish.
abstract: The sea robin (Prionotus evolans), a representative teleost fish, was found to undergo the hapten-carrier effect, suggestive of T-B cell cooperativity, in vivo with dinitrophenyl as the hapten and bovine gamma-globulin or bovine serum albumin as carriers. In contrast to mammalian systems, the secondary anti-hapten response in the sea robin was found to involve exclusively high molecular weight antibody.
mesh_terms: D000042:Absorption; D000818:Animals; D000906:Antibodies / Q000032:analysis; D000917:Antibody Formation; D002417:Cattle / Q000276:immunology; D002499:Centrifugation, Density Gradient; D003090:Coliphages / Q000276:immunology; D004140:Dinitrophenols / Q000276:immunology*; D005399:Fishes / Q000276:immunology*; D006241:Haptens; D007106:Immune Sera / Q000032:analysis; D007114:Immunization; D007122:Immunoelectrophoresis; D009500:Neutralization Tests; D012710:Serum Albumin, Bovine / Q000276:immunology*; D005719:gamma-Globulins / Q000276:immunology*
chemical_list: D000906:Antibodies; D004140:Dinitrophenols; D006241:Haptens; D007106:Immune Sera; D005719:gamma-Globulins; D012710:Serum Albumin, Bovine