title: Penicillinase-producing Neisseria gonorrhoeae.
abstract: Repeated failure of penicillin G treatment in a man with gonorrhoeal urethritis prompted penicillin sensitivity testing of the responsible strain of Neisseria gonorrhoeae. Disc diffusion sensitivity testing showed complete resistance to 10 mug of penicillin G. The organism produced penicillinase.
mesh_terms: D000328:Adult; D006069:Gonorrhea / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000201:enzymology / Q000302:isolation & purification; D010402:Penicillin G Procaine / Q000494:pharmacology* / Q000627:therapeutic use; D010403:Penicillin Resistance; D010405:Penicillinase / Q000096:biosynthesis*
chemical_list: D010402:Penicillin G Procaine; D010405:Penicillinase