Esterase polymorphism and sensitivity to Dursban organophosphorus insecticide in Culex pipiens pipiens populations.
Esterase polymorphism and Dursban (O,O-dimethyl-2-pyridylphosphorothioate) sensitivity have been investigated in 12 natural populations and three laboratory strains of Culex pipiens pipiens. This mosquito has two esterase loci, Est-1 and Est-2, which were shown to code esterases of the B group (aliesterases) but not cholinesterases. No correlation between Est-1 polymorphism and Dursban sensitivity was found, but the increase of the Est-2(0.64) allele in the populations less sensitive to Dursban was highly significant (r = -0.9850 for 6 df).
D000483:Alleles; D000818:Animals; D004390:Chlorpyrifos; D002802:Cholinesterases / Q000378:metabolism; D003465:Culex / Q000201:enzymology*; D004950:Esterases / Q000378:metabolism*; D007527:Isoenzymes / Q000378:metabolism; D007814:Larva; D010641:Phenotype; D011110:Polymorphism, Genetic; D013045:Species Specificity
D007527:Isoenzymes; D004950:Esterases; D002802:Cholinesterases; D004390:Chlorpyrifos