title: Comparative in vitro microbiological activity and stability of cefaclor.
abstract: The in vitro activity of cefaclor was compared with that of cephalexin and cephradine. This new antibiotic was the most active of the oral agents against Haemophilus influenzae (especially non-beta-lactamase producing strains). It was also significantly more active against N. gonorrhoeae and the Enterobacteriaceae. The instability in agar raises some issues that need further study.
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D002433:Cefaclor / Q000494:pharmacology*; D002506:Cephalexin / Q000031:analogs & derivatives* / Q000494:pharmacology; D002515:Cephradine / Q000494:pharmacology; D004355:Drug Stability; D004755:Enterobacteriaceae / Q000187:drug effects; D006193:Haemophilus influenzae / Q000187:drug effects; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects
chemical_list: D002433:Cefaclor; D002515:Cephradine; D002506:Cephalexin