[Differential diagnosis of acute viral hepatitis and liver cirrhosis with severe activity (author's transl)].
Results of biochemical tests in 61 patients with acute viral hepatitis resp. 63 patients with subacute hepatitis were compared with laboratory findings of 27 patients with liver cirrhosis in the stage of severe activity of the disease. In acute and subacute viral hepatitis was the activity of GPT and CHE significantly higher than in active cirrhosis of the liver. In contrast to these findings was the activity of GLDH and the blood level of bilirubin in both groups of patients similar and for the differential diagnosis of no importance. Low albumin, high gammaglobulin and significant increase of IgG and IgA fractions of immunglobulins in serum are additionally to the results of the activity of some serum enzymes for the diagnosis of active liver cirrhosis in comparison to acute and subacute viral hepatitis of greatest value.
D000208:Acute Disease; D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001706:Biopsy; D001798:Blood Proteins / Q000032:analysis; D002802:Cholinesterases / Q000097:blood; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D005969:Glutamate Dehydrogenase / Q000097:blood; D006506:Hepatitis A / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007770:L-Lactate Dehydrogenase / Q000097:blood; D010535:Laparoscopy; D008103:Liver Cirrhosis / Q000097:blood / Q000175:diagnosis*; D008875:Middle Aged; D012709:Serum Albumin / Q000032:analysis; D005719:gamma-Globulins / Q000032:analysis
D001798:Blood Proteins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012709:Serum Albumin; D005719:gamma-Globulins; D007770:L-Lactate Dehydrogenase; D005969:Glutamate Dehydrogenase; D000410:Alanine Transaminase; D002802:Cholinesterases; D000469:Alkaline Phosphatase; D001663:Bilirubin
Zur Differentialdiagnose: akute Virushepatitis--akuter Schub bei Leberzirrhose