Glutamine synthetase and glutamate synthase activities during growth and sporulation in Bacillus subtilis.
Glutamine synthetase in Bacillus subtilis 168 was repressed to a greater extent by L-glutamine or L-arginine than by ammonia when each was used as sole nitrogen source. It was derepressed when either L-glutamate or nitrate was used as nitrogen source. Glutamate synthase was repressed by  L-glutamate or L-arginine and, to a lesser extent, by L-glutamine but was derepressed during growth with ammonia or nitrate. Glutamine synthetase activity was unaltered during the onset of sporulation. Glutamate synthase activity, however, underwent a small and apparently transient increase in bacteria induced to sporulate by nitrogen limitation.
D001412:Bacillus subtilis / Q000201:enzymology* / Q000254:growth & development / Q000502:physiology; D005970:Glutamate Synthase / Q000378:metabolism*; D005974:Glutamate-Ammonia Ligase / Q000378:metabolism*; D013171:Spores, Bacterial / Q000201:enzymology; D000637:Transaminases / Q000378:metabolism*
D005970:Glutamate Synthase; D000637:Transaminases; D005974:Glutamate-Ammonia Ligase