Irradiation treatment of inoperable squamous cell carcinomas of the oral cavity and oropharynx after partial synchronisation.
Bleomycin has proved to be an efficacious cyclus-synchronising drug in the sense that it arrests the radiosensitive G2-phase directly. In comparison with 5-Fluor-uracil, Bleomycin possesses a more effective cell-kinetics. An analytical clinical remission with the application of Bleomycin, coupled with a higher incidence of local and general side effects.
D001761:Bleomycin / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D005472:Fluorouracil / Q000627:therapeutic use*; D008938:Mitosis; D009062:Mouth Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D010610:Pharyngeal Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D013997:Time Factors
D001761:Bleomycin; D005472:Fluorouracil