Treatment of ulcerative colitis with oral disodium cromoglycate. A double-blind controlled trial.
Twelve patients with ulcerative protocolitis were treated for six months with each of oral disodium cromoglycate (2 g/day) and placebo in a double-blind cross-over trial. The active drug significantly improved the patients' sense of well-being and the signoidoscopic and rectal biopsy appearances. Orally administered disodium cromoglycate may have a place in the long-term management of colitis.
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002986:Clinical Trials as Topic; D003093:Colitis, Ulcerative / Q000188:drug therapy* / Q000473:pathology; D004205:Cromolyn Sodium / Q000008:administration & dosage* / Q000627:therapeutic use; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos; D012007:Rectum / Q000473:pathology; D012812:Sigmoidoscopy; D013997:Time Factors
D010919:Placebos; D004205:Cromolyn Sodium