Serum enzymes in ovarian carcinoma.
The following enzymatic activities were measured in serum of patients with benign and malignant ovarian tumors before treatment: alkaline and acid phosphatases, aspartyl (AspAT) and alanyl (AlAT) aminotransferases, leucyl (LAP) and alanyl (AAP) aminopeptidases, lactate dehydrogenase (LDH), gamma-glutamyl transpeptidase, cathepsin, alkaline ribonuclease (RNase) and beta-glucuronidase. It was shown that at least three determinations (phosphatases and LAP) are practically useless in a discrimination between the examined groups. RNase in combination with AspAT (AlAT) or RNase with AAP and LDH were found to give the best results as marker enzymes.
D000230:Adenocarcinoma / Q000201:enzymology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000626:Aminopeptidases / Q000097:blood*; D002403:Cathepsins / Q000097:blood; D005260:Female; D005966:Glucuronidase / Q000097:blood; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008875:Middle Aged; D009214:Myoma / Q000201:enzymology*; D010051:Ovarian Neoplasms / Q000201:enzymology*; D012260:Ribonucleases / Q000097:blood; D000637:Transaminases / Q000097:blood*; D005723:gamma-Glutamyltransferase / Q000097:blood
D007770:L-Lactate Dehydrogenase; D005723:gamma-Glutamyltransferase; D000637:Transaminases; D012260:Ribonucleases; D005966:Glucuronidase; D002403:Cathepsins; D000626:Aminopeptidases