[Effects of somatostatin upon prolactin secretion both in normal subjects and in patients presenting pituitary adenoma (author's transl)].
In normal subjects somatostatin cannot modify the plasma levels of prolactin when they are in a normal range or when they are pharmacologically increased. In the case of pituitary adenoma (prolactinic or eosinophilic), the response of prolactin to somatostatin varies widely. In some patients there is a marked decrease of the prolactin levels while in others no modification is observed.
D000172:Acromegaly / Q000097:blood; D000236:Adenoma / Q000097:blood; D000239:Adenoma, Acidophil / Q000097:blood; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000097:blood; D011388:Prolactin / Q000097:blood / Q000378:metabolism*; D013004:Somatostatin / Q000008:administration & dosage / Q000494:pharmacology*
D013004:Somatostatin; D011388:Prolactin
Effets de la somatostatine sur la sécrétion de prolactine. Etude chez des sujets normaux et chez des patients ayant un adénome hypophysaire.