[Congenital toxoplasmosis with activation of extramedullary hematopoiesis in a premature infant].
An immature neonate surviving for 45 minutes showed a generalized hydrops and hepatosplenomegaly unassociated with blood incompatibility. A marked activation of extramedullary haematopoiesis was observed not only in its liver and spleen, but also in the interstitium of the lungs, pancreas, kidneys, and adrenal glands. In addition, extensive necrosis of the brain and diffuse nonsuppurative myositis and myocarditis were found. All the changes were due to congenital toxoplasmosis, which has been confrimed by the findings of occasional pseudocysts within the placenta, by the result of the parasitologic examination of the brain of the autopsied infant and by serological examination of the mother post partum.
D004487:Edema / Q000150:complications; D005260:Female; D006410:Hematopoiesis; D006529:Hepatomegaly / Q000150:complications; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000473:pathology*; D013163:Splenomegaly / Q000150:complications; D013194:Staining and Labeling; D014125:Toxoplasmosis, Congenital / Q000473:pathology*
Vrozená toxoplazmóza s aktivaci extramedulárni krvetvorby u nedonoseného ditĕte