Psychotropic effect of antiepileptic drugs.
Eighteen controlled studies investigating the psychotropic effect of anti-epileptic drugs are critically reviewed. The neurochemical evidence for existence of psychotropic properties is still speculative. It seems questionable on the basis of this survey that there exist genuine psychotropic effects of antiepileptic drugs, which are not related to antiepileptic efficacy and/or differences in toxicity.
D000927:Anticonvulsants / Q000494:pharmacology*; D002220:Carbamazepine / Q000494:pharmacology; D005013:Ethosuximide / Q000494:pharmacology; D006801:Humans; D008606:Mental Processes / Q000187:drug effects*; D010555:Personality Inventory; D010634:Phenobarbital / Q000494:pharmacology; D010672:Phenytoin / Q000494:pharmacology; D011569:Psychiatric Status Rating Scales; D011619:Psychotropic Drugs; D013843:Thiazines / Q000494:pharmacology; D014635:Valproic Acid / Q000494:pharmacology
D000927:Anticonvulsants; D011619:Psychotropic Drugs; D013843:Thiazines; D002220:Carbamazepine; D005013:Ethosuximide; D014635:Valproic Acid; D010672:Phenytoin; D010634:Phenobarbital