Cryptorchid human testis after HCG treatment: histological study on Sertoli cells.
Histological studies have been carried out on Sertoli cells in cryptorchid patients after long-term HCG treatment. Morphological studies revealed the absence of differentiation of mature Sertoli cells. This behaviour with the persistence of fibroblast cells in the interstitium after long-term HCG treatment suggests that the morphological action of HCG on the Sertoli cells is closely correlated with the maturation of the Leydig cells, particularly with their androgen production.
D002648:Child; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D003456:Cryptorchidism / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008297:Male; D012708:Sertoli Cells / Q000187:drug effects* / Q000473:pathology
D006063:Chorionic Gonadotropin