Pathogenesis of essential hypertension.
It is proposed that essential hypertension is an exaggeration of the tendency for blood-pressure to rise with age, that it results from a repeated sequence in which a small rise in pressure, possibly resulting from an autonomic nervous overactivity, produces changes in the kidney which maintain the rise of pressure and become the basis for a further rise.
D000367:Age Factors; D001341:Autonomic Nervous System / Q000503:physiopathology; D001794:Blood Pressure; D002196:Capillaries / Q000503:physiopathology; D004777:Environment; D005919:Glomerular Filtration Rate; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000235:genetics / Q000503:physiopathology; D007668:Kidney / Q000098:blood supply / Q000503:physiopathology; D014655:Vascular Resistance