The peripheral odontogenic fibroma.
An extensive review of the English-language literature has produced only five undoubted cases of peripheral odontogenic fibroma. This article reports ten new cases. The age and sex of the patients and the distribution by site and histology of the lesions are compared with those of other cases of bifrous tumors and neoplasms of odontogenic origin. It is postulated that this lesion may be more closely related to the fibrous euplis than was previously realized. Both lesions show hyperplasia of the basal layer of the covering ipithelium into double strands resembling odontogenic epithelium. It is suggested that this hyperplasia may be related to induction of the covering epithelium by primitive ectomesenchymal remnants within the gingivae. Proliveration of odontogenic rests within the peripheral odontogenic frbroma may be related to the same stimulus.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001485:Basement Membrane; D002114:Calcinosis / Q000473:pathology; D002467:Cell Nucleus / Q000648:ultrastructure; D002648:Child; D003094:Collagen / Q000032:analysis; D003238:Connective Tissue / Q000648:ultrastructure; D003239:Connective Tissue Cells; D003593:Cytoplasm / Q000648:ultrastructure; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D005887:Gingival Neoplasms / Q000473:pathology*; D006003:Glycogen / Q000032:analysis; D006801:Humans; D008297:Male; D008334:Mandible / Q000648:ultrastructure; D008339:Mandibular Neoplasms / Q000473:pathology*; D008437:Maxilla / Q000648:ultrastructure; D008441:Maxillary Neoplasms / Q000473:pathology*; D008875:Middle Aged; D009808:Odontogenic Tumors / Q000473:pathology*; D012737:Sex Factors; D013194:Staining and Labeling
D006003:Glycogen; D003094:Collagen