[Is the prostatic adenoma of hormonal origin].
Prostatic adenoma develops at the site of the periurethral glands. The concentration of 5alpha-dihydrotestosterone seems greater at the center of the adenoma than in the overlying prostate. This suggests that medical treatment of prostatic adenoma might be feasible using substances inhibiting the 5alpha-reduction of testosterone.
D000368:Aged; D000818:Animals; D002369:Castration; D013196:Dihydrotestosterone / Q000378:metabolism*; D004285:Dogs; D004967:Estrogens / Q000494:pharmacology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000187:drug effects / Q000378:metabolism*; D011470:Prostatic Hyperplasia / Q000209:etiology* / Q000378:metabolism; D013739:Testosterone / Q000378:metabolism*
D004967:Estrogens; D013196:Dihydrotestosterone; D013739:Testosterone
L'adénome prostatique est-il d'origine hormonale?