title: Menstrual blood-loss with intrauterine devices.
abstract: The effect of three intrauterine contraceptive devices (I.U.D.)-Lippes D, Dalkon Shield, and Copper 7-on menstrual blood-loss has been studied serially by objective methods in 279 women. All the women had a minimum of two cycles following delivery, abortion, cessation of lactation, or previous pill or I.U.D. use. All pads and tampons used for two further menstrual cycles before and for 12 cycles after I.U.D. insertion were collected, and the blood-loss was measured by extracting the haemoglobin by conversion to alkaline haematin. Mean menstrual blood-loss increased with all three devices. The amount of loss, the percentage of women losing more than 80 ml, the decline in haemoglobin concentration, and the incidence of anaemia during the 12 cycles following insertion were all greater among users of the Lippes Loop than of the Copper 7 with generally intermediate values for Dalkon Shield users. The mean increases in blood-loss were: for parous women fitted with the Lippes Loop, 48 ml, with the Dalkon Shield, 34 ml, and with the Copper 7, 18 ml; for nulliparae fitted with the small size of Dalkon Shield, 27 ml, and, with the Copper 7, 19 ml.
mesh_terms: D001800:Blood Specimen Collection; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007434:Intrauterine Devices / Q000009:adverse effects*; D008297:Male; D008595:Menorrhagia / Q000209:etiology*; D052576:Menstrual Hygiene Products; D008598:Menstruation; D010298:Parity; D013997:Time Factors
chemical_list: D006454:Hemoglobins