title: Aggravation of psoriasis and occurrence of psoriasiform cutaneous eruptions induced by practolol (Eraldin).
abstract: Twelve patients with cutaneous and/or eye symptoms caused by practolol have been studied. The morphological appearance of the skin eruptions was psoriasiform in 5, vesiculo-papular in one, and exfoliating dermatitis was seen in 2 patients. Keratoconjunctivitis sicca was the only adverse reaction to practolol in one and was present in 3 additional patients. Practolol was found to aggravate existing psoriasis in 3 patients and render it extremely refractory to therapy.
mesh_terms: D000328:Adult; D000368:Aged; D003875:Drug Eruptions / Q000473:pathology; D005260:Female; D006801:Humans; D007637:Keratoconjunctivitis / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D011217:Practolol / Q000009:adverse effects*; D011565:Psoriasis / Q000473:pathology; D012867:Skin / Q000473:pathology; D012882:Skin Tests
chemical_list: D011217:Practolol