[Results of a controlled epidemiological trial of the application of placental gamma globulin in foci of meningococcal infection].
Controlled epidemiological trial was applied to the study of the use of placental gamma-globulin for prophylaxis of generalized forms of meningococcus infection in the foci (creches and kindergartens). A group of the vaccinated children (16 140) and control group (16 080) were the same age and sex. Gamma-globulin was administered in a dose of 3 ml to every other child attending creches and kindergartens not later than the 10th day after the patient's isolation. It was shown that the efficacy coefficient of gamma-globulin in the foci of meningococcus infection constituted 68% (the efficacy index was 3.2) for one month after the administration.
D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008589:Meningococcal Infections / Q000517:prevention & control*; D010920:Placenta; D005719:gamma-Globulins / Q000627:therapeutic use*
D005719:gamma-Globulins
Itogi kontroliruemogo épidemiologicheskogo opyta po primeneniiu platsentarnogo gamma-globulina v ochagakh meningokokkovoĭ infektsii