[Effect of hypothalamic implants changing monoamine levels on continuous estrus in rats induced by androgen treatment in the neonatal period].
The constant estrus induced by neonatal androgenization in the female rat may be disrupted following a drug-induced change of the monoamine levels in the preoptic area and arcuate nucleus of the median eminence. The most precise effect is obtained with 5-HT. This is in favour of a predominant alteration of the serotonergic system which seems to be involved in the sexual differentiation of the brain.
D018663:Adrenergic Agents / Q000494:pharmacology*; D000818:Animals; D000831:Animals, Newborn; D004298:Dopamine / Q000494:pharmacology; D004343:Drug Implants; D004971:Estrus / Q000187:drug effects*; D005260:Female; D010134:Fenclonine / Q000494:pharmacology*; D006892:Hydroxydopamines / Q000494:pharmacology; D007031:Hypothalamus; D018377:Neurotransmitter Agents / Q000494:pharmacology*; D009638:Norepinephrine / Q000494:pharmacology; D011247:Pregnancy; D011301:Preoptic Area; D051381:Rats; D012110:Reserpine / Q000494:pharmacology; D012701:Serotonin / Q000494:pharmacology; D013739:Testosterone / Q000494:pharmacology*
D018663:Adrenergic Agents; D004343:Drug Implants; D006892:Hydroxydopamines; D018377:Neurotransmitter Agents; D012701:Serotonin; D013739:Testosterone; D012110:Reserpine; D010134:Fenclonine; D004298:Dopamine; D009638:Norepinephrine
Effets d'implantations hypothalamiques agissant sur les monoamines sur l'oestrus permanent de la ratte androgénisée à la période néo-natale