Home parenteral nutrition in treatment of severe radiation enteritis.
Ten patients with radiation enteritis unresponsive to conventional medical and surgical therapy were put on long-term parenteral nutrition at home. Six of the patients are alive at home; four patients died, two from recurrent cancer. Some of the patients have been able to resume oral intake, but none have been able to discontinue parenteral nutrition. Fistulas healed or had a marked decrease in output. Two patients in our series were given prednisone and slinical improvement of radiation enteritis with this therapy.
D000008:Abdominal Neoplasms / Q000532:radiotherapy; D000328:Adult; D000368:Aged; D004751:Enteritis / Q000209:etiology* / Q000628:therapy; D005260:Female; D006701:Home Nursing; D006801:Humans; D008297:Male; D008875:Middle Aged; D010288:Parenteral Nutrition; D010386:Pelvic Neoplasms / Q000532:radiotherapy; D011241:Prednisone / Q000627:therapeutic use; D011878:Radiotherapy / Q000009:adverse effects*; D012460:Sulfasalazine / Q000627:therapeutic use
D012460:Sulfasalazine; D011241:Prednisone