title: Aldehyde-fuchsin staining of antral endocrine cells.
abstract: Correlative studies have been made to identify the endocrine cells stained by Aldehyde-Fuchsin (AF) in the cat and human antral mucosa. D-cells weakly stained by AF after oxidation: this staining might be related to the disulphide group present in the molecule of Somatostatin (the hypothalamic hormone recently localized in D-cells). The gastrin-producing G-cells were on the contrary strongly stained (without oxidation) in tissues fixed in Helly-fluid. Histochemical investigations on the mechanism of such staining lead to the conclusion that it might be related to affinity of the stain for hidden acidic groups.
mesh_terms: D000447:Aldehydes; D000818:Animals; D002415:Cats; D005753:Gastric Mucosa / Q000032:analysis*; D005755:Gastrins / Q000032:analysis; D005768:Gastrointestinal Hormones / Q000032:analysis*; D006801:Humans; D011706:Pyloric Antrum / Q000032:analysis*; D012394:Rosaniline Dyes; D013004:Somatostatin / Q000032:analysis; D013194:Staining and Labeling
chemical_list: D000447:Aldehydes; D005755:Gastrins; D005768:Gastrointestinal Hormones; D012394:Rosaniline Dyes; D013004:Somatostatin