[Biochemical and physiocochemical characteristics of a type C virus isolated from spontaneous lymphosarcoma of CC57Br strain mice].
The properties of murine oncornavirus produced by cells of spontaneous lymphosarcroma of CC57Br mice are described. In addition to the properties common for C-type RNA tumor viruses such as 60-70 S high molecular weight RNA, the presence of RNA-directed DNA polymerase and murine gs I (intraspecies) antigen and typical morphology in electron microscope, etc., the virus under study is characterized by instability of virions, unusual features of the DNA polymerase system and by the absence of demonstrable oncogenicity either in laboratory animals or in tissue cultures.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D004591:Electrophoresis, Polyacrylamide Gel; D008228:Lymphoma, Non-Hodgkin / Q000382:microbiology*; D051379:Mice; D008815:Mice, Inbred Strains; D008854:Microscopy, Electron; D010455:Peptides / Q000032:analysis; D012367:RNA, Viral / Q000032:analysis; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D012190:Retroviridae / Q000032:analysis / Q000201:enzymology / Q000302:isolation & purification / Q000648:ultrastructure; D014316:Tritium; D014529:Uridine; D014764:Viral Proteins / Q000032:analysis
D000956:Antigens, Viral; D010455:Peptides; D012367:RNA, Viral; D014764:Viral Proteins; D014316:Tritium; D012194:RNA-Directed DNA Polymerase; D014529:Uridine
Biokhimicheskie i fiziko-khimicheskie kharakteristiki virusa tipa C, vydelennogo iz spontannoĭ limfosarkomy mysheĭ linii CC57Br