[Reproduction of the anaphylactic reaction of isolated human smooth muscle organs and the effect of several adrenotropic substances].
A comparative study was carried out of passive sensitization of the lungs, bronchi, small and large intestine by the blood sera of patients sensitive to ambrosia pollen. Passive sensitization and subsequent anaphylactic contraction were reproduced on the isolated bronchi, lungs and the ileum. Development of this reaction was less constant in the large intestine, jejunum and the appendix. The value of anaphylactic reaction of human smooth muscle displayed significant changes with the treatment of the muscles by agents selectively acting on the beta-adrenergic receptors of these organs.
D000707:Anaphylaxis / Q000188:drug therapy / Q000276:immunology* / Q000378:metabolism; D001065:Appendix / Q000276:immunology; D001980:Bronchi / Q000276:immunology; D002986:Clinical Trials as Topic; D006636:Histamine Release; D006801:Humans; D007116:Immunization, Passive; D066298:In Vitro Techniques; D007420:Intestine, Large / Q000276:immunology; D007421:Intestine, Small / Q000276:immunology; D007545:Isoproterenol / Q000627:therapeutic use; D008168:Lung / Q000276:immunology / Q000378:metabolism; D009130:Muscle, Smooth / Q000276:immunology*; D010646:Phentolamine / Q000627:therapeutic use; D010656:Phenylephrine / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use; D012007:Rectum / Q000276:immunology; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy / Q000276:immunology* / Q000378:metabolism
D010656:Phenylephrine; D011433:Propranolol; D007545:Isoproterenol; D010646:Phentolamine
Vosproizvedenie anafilakticheskoĭ reaktsii izolirovannykh gladkonyshechnykh organov cheloveka i vliianie na nee nekotorykh adrenotropnykh veshchestv