title: Verapamil in the management of hypertensive patients.
abstract: The hypotensive action of verapamil given orally was assessed in the outpatient management of patients with raised blood pressure, in a single blind study. Twenty-six hypertensive patients on no therapy, 14 on beta blockers and eight on methyldopa were more satisfactorily controlled when verapamil was substituted for the initial drug. There was a marked reduction in the number of side-effects, and the drug was given in many situations where beta blockade was contra-indicated.
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008750:Methyldopa / Q000627:therapeutic use; D008875:Middle Aged; D014700:Verapamil / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000319:Adrenergic beta-Antagonists; D008750:Methyldopa; D014700:Verapamil