Clearance of antibody and complement in serum after challenge of mice previously vaccinated or infected with influenza virus.
Mice previously vaccinated or convalescent after infection with mouse-adapted influenza virus were challenged by various routes with live or inactivated virus. The levels of haemagglutination inhibiting and complement-fixing antibodies and complement in serum were found to decrease distinctly within several hours after challenge: the reconstitution to initial levels occurred within three days.
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis*; D000936:Antigen-Antibody Complex; D003168:Complement Fixation Tests; D003165:Complement System Proteins / Q000378:metabolism*; D003289:Convalescence; D006385:Hemagglutination Inhibition Tests; D009980:Influenza A virus / Q000276:immunology*; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000276:immunology*; D014611:Vaccination
D000914:Antibodies, Viral; D000936:Antigen-Antibody Complex; D003165:Complement System Proteins