title: [Experience in the treatment of malignant obstructions of the vena cava superior by means of chemotherapeutic decompression and subsequent irradiation].
abstract: The clinical picture, pathogenesis and etiology of malignant vena cava obstruction are described. The importance of using modern methods to treat this critical condition is emphasized. Furthermore, the authors examine the principles of chemotherapeutic decompression followed by irradiation. A single dose of nitrogen mustard was applied intravenously, followed by irradiation, on 24 patients with malignant vena caval obstruction. The results of this treatment are presented. The effect of this treatment was controlled by measuring the venous blood pressure and with chest X-rays. The authors conclude, that this method of decompression is successful in the palliative treatment of this syndrom.
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000150:complications; D001984:Bronchial Neoplasms / Q000150:complications; D002496:Central Venous Pressure; D003664:Decompression; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000150:complications; D008297:Male; D008466:Mechlorethamine / Q000627:therapeutic use*; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010166:Palliative Care; D011879:Radiotherapy Dosage; D012039:Regional Blood Flow; D013274:Stomach Neoplasms / Q000150:complications; D013899:Thoracic Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy; D013964:Thyroid Neoplasms / Q000150:complications; D014652:Vascular Diseases / Q000209:etiology / Q000628:therapy*; D014683:Vena Cava, Superior / Q000503:physiopathology*
chemical_list: D008466:Mechlorethamine
vernacular_title: Erfahrungen bei der Behandlung maligner Obstruktionen der oberen Hohlvene durch chemotherapeutisches Dekompressionsverfahren und Nachbestrahlung