[Reduction of myocardial reperfusion damage using hypocalcemic, hyperkalemic, alkaline blood during post-ischemic oxygen resaturation].
Postischemic myocardial depression is largely caused by a reperfusion injury which can be avoided almost completely by initial reoxygenation with hypocalcemic, hyperkalemic, alkalotic blood. Reperfusate modification resulted in postischemic myocardial performance comparable to that achieved in hearts receiving continuous coronary perfusion.
D000818:Animals; D002118:Calcium / Q000097:blood*; D003326:Coronary Circulation; D004285:Dogs; D006324:Heart Arrest, Induced / Q000009:adverse effects*; D006863:Hydrogen-Ion Concentration; D009203:Myocardial Infarction / Q000517:prevention & control*; D009206:Myocardium / Q000378:metabolism; D010101:Oxygen Consumption; D010477:Perfusion; D011188:Potassium / Q000097:blood*
D011188:Potassium; D002118:Calcium
Minderung des myokardialen Reperfusionsschadens mit hypocalcämischen, hyperkaliämischen, alkalischem Blut während der postischämischen Wiederaufsättigung mit Sauerstoff.