title: [Reproduction of leukovirus RD-114 in diploid and heteroploid human cells].
abstract: The capacity of leukovirus RD-114 to replicate in human embryo lung diploid cell cultures and continuous human angiosarcoma cell cultures (AS and 709 lines). Differences in the capacity to support the virus reproduction were observed in the two strains of human embryo lung cells (HEL-1 and HEL-3) and the two continuous angiosarcoma cell lines. No virus reporduction was observed in mouse and rat cell cultures. No cytopathic or transformation changes were caused by the virus in any of the systems examined.
mesh_terms: D000818:Animals; D002460:Cell Line; D002869:Chromosome Aberrations; D004171:Diploidy; D006394:Hemangiosarcoma; D006801:Humans; D007668:Kidney; D008168:Lung / Q000196:embryology; D051379:Mice / Q000196:embryology; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D051381:Rats / Q000196:embryology; D012190:Retroviridae / Q000201:enzymology / Q000254:growth & development*; D012208:Rhabdomyosarcoma / Q000382:microbiology; D014779:Virus Replication
chemical_list: D012194:RNA-Directed DNA Polymerase
vernacular_title: Reproduktsiia leĭkovirusa RD-114 v diploidnykh i geteroploidnykh kletkakh cheloveka