[Absence of the inhibitor factor of the Mullerian structures. Report of a case].
A 30 year old patient with normal masculine phenotype, karyotype 46 XY with a congenital left inguinal hernia, was studied. This hernia contained (at surgery): uterus, tubes and a hypoplasic vagina, as well as testis. The Müllerian structures and the right testicle, were resected, and left orchidopexy was performed. FSH, LH, testosterone, prolactine, B-HCG in blood by radioimmunoanalysis, total estrogens, 17-ketosteroids and 17-hydroxicorticosteroids in urine, were all normal. Roentgenologic and endoscopic urologic studies were normal. A post-operative study of semen showed moderate oligospermia. The factors involved in masculine sexual differentiation, were reviewed, specially the inhibitory factor of Müllerian structures.
D000328:Adult; D003456:Cryptorchidism / Q000209:etiology / Q000601:surgery*; D012734:Disorders of Sex Development / Q000209:etiology / Q000601:surgery*; D006552:Hernia, Inguinal / Q000151:congenital / Q000601:surgery*; D006801:Humans; D007621:Karyotyping; D008297:Male; D009095:Mullerian Ducts / Q000002:abnormalities*; D012733:Sex Differentiation
Ausencia de factor inhibidor de estructuras de Müller. Informe de un caso.