Pyridine nucleotide involvement in rat hepatic microsomal drug metabolism--IV. Inhibition of aminopyrine and ethylmorphine-N-demethylases by 2.6-dihydroxy-acetophenone.
D000098:Acetophenones / Q000494:pharmacology*; D000633:Aminopyrine N-Demethylase / Q000037:antagonists & inhibitors*; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D005037:Ethylmorphine-N-Demethylase / Q000037:antagonists & inhibitors*; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008297:Male; D008954:Models, Biological; D009243:NAD / Q000378:metabolism*; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism; D009249:NADP / Q000378:metabolism*; D010089:Oxidoreductases, N-Demethylating / Q000037:antagonists & inhibitors*; D051381:Rats
D000098:Acetophenones; D009243:NAD; D009249:NADP; D003577:Cytochrome P-450 Enzyme System; D010089:Oxidoreductases, N-Demethylating; D000633:Aminopyrine N-Demethylase; D005037:Ethylmorphine-N-Demethylase; D009247:NADH, NADPH Oxidoreductases