Nitrogen metabolite repression of nitrate reductase in Neurospora crassa: effect of the gln-1a locus.
Nicotinamide adenine dinucleotide phosphate (reduced form)-nitrate reductase was freed from ammonium repression in a Neurospora crassa mutant having drastically lowered glutamine synthetase activity, gln-1a. The general phenomenon of nitrogen metabolite repression required glutamine or some aspect of glutamine metabolism.
D004794:Enzyme Repression; D005796:Genes; D005974:Glutamate-Ammonia Ligase / Q000378:metabolism*; D005973:Glutamine / Q000378:metabolism*; D009154:Mutation; D009491:Neurospora / Q000201:enzymology*; D009492:Neurospora crassa / Q000201:enzymology* / Q000235:genetics; D009565:Nitrate Reductases / Q000096:biosynthesis*
D005973:Glutamine; D009565:Nitrate Reductases; D005974:Glutamate-Ammonia Ligase