Molecular hybridization study of cells producing oncornaviruses type D.
Five human cell lines producing oncornaviruses type D were studied by the method of molecular hybridization of viral and cellular nucleic acids. Repeated sequences of viral genome equivalents were found in nuclear DNA and numerous copies of viral genome were found in the cytoplasm. The viruses produced by the cell lines were found to be identical or closely related as regards nucleotide sequences of their genomes.
D000818:Animals; D002294:Carcinoma, Squamous Cell; D002460:Cell Line; D002642:Chick Embryo; D004279:DNA, Viral / Q000378:metabolism; D006367:HeLa Cells / Q000382:microbiology; D006801:Humans; D007822:Laryngeal Neoplasms; D009693:Nucleic Acid Hybridization; D009858:Oncogenic Viruses / Q000201:enzymology / Q000378:metabolism / Q000502:physiology*; D012367:RNA, Viral / Q000378:metabolism; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D014776:Virus Cultivation; D014779:Virus Replication
D004279:DNA, Viral; D012367:RNA, Viral; D012194:RNA-Directed DNA Polymerase