A thiol-labelling reagent and reactivity probe containing electrophilic mercury and a chromophoric leaving group.
2-(2'-Pyridylmercapto)mercuri-4-nitrophenol was synthesized and evaluated as a thiol-labelling reagent containing a chromophoric leaving group and as a reactivity probe by studies on its reactions with 2-mercaptoethanol and with papain (EC 3.4.22.2).
D055598:Chemical Phenomena; D002621:Chemistry; D002730:Chloromercurinitrophenols; D006863:Hydrogen-Ion Concentration; D008623:Mercaptoethanol; D010206:Papain; D010663:Phenylmercury Compounds / Q000138:chemical synthesis; D011725:Pyridines / Q000138:chemical synthesis; D013057:Spectrum Analysis; D013438:Sulfhydryl Compounds
D002730:Chloromercurinitrophenols; D010663:Phenylmercury Compounds; D011725:Pyridines; D013438:Sulfhydryl Compounds; D008623:Mercaptoethanol; D010206:Papain