Soluble fibrinogen/fibrin complexes in pre-eclampsia.
Significantly increased concentrations of soluble fibrinogen/fibrin complexes were found in plasma samples from ten normal pregnant women when compared with ten non-pregnant age-matched controls. In ten women with pre-eclampsia mean soluble complex concentration was more than three times that in the age, parity, and gestation matched pregnant controls. Soluble fibrinogen/fibrin complexes are also found in the plasma of patients in various hypercoagulable and thrombotic states, including disseminated intravascular coagulation. These findings provide additional evidence that pre-eclampsia is associated with disseminated intravascular coagulation.
D000941:Antigens / Q000032:analysis; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D005260:Female; D005337:Fibrin / Q000032:analysis* / Q000276:immunology; D005340:Fibrinogen / Q000032:analysis* / Q000276:immunology; D006801:Humans; D007105:Immune Complex Diseases / Q000097:blood; D011225:Pre-Eclampsia / Q000097:blood* / Q000150:complications*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood; D012995:Solubility
D000941:Antigens; D005337:Fibrin; D005340:Fibrinogen