Studies on the reaction between pyridine nucleotides and mercury compounds in artificial intracellular and extracellular fluids.
The strong complex formations of pyridine nucleotides with mercury compounds were demonstrated in artificial intracellular fluid containing oxianions (HPO42-, HCO3-), while those in artificial extracellular fluid were considerably weaker. Dissociation constants (K) of the complexes of [MC.NADP], [MC.NADPH], [MC.NAD], [MC.NADH], [MC.adenine], and [MC.nicotinamide mononucleotide] were found to be 1.0 x 10(-4), 2.6 x 10(-5), 1.2 x 10(-4), 2.9 x 10(-5), 7.2 x 10(-6), and 3.8 x 10(-3), respectively in phosphate buffer (43 mM, pH 8.0).
D005110:Extracellular Space; D007424:Intracellular Fluid; D008628:Mercury; D009243:NAD / Q000032:analysis; D009249:NADP / Q000032:analysis; D010710:Phosphates; D012965:Sodium Chloride
D010710:Phosphates; D009243:NAD; D012965:Sodium Chloride; D009249:NADP; D008628:Mercury