title: Influence of flunitrazepam on body functions.
abstract: The effects of intravenous flunitrazepam (Rohypnol, Roche) on various body functions were studied and the following conclusions were reached: it is a very potent sedative/hypnotic even in small doses, it may cause depression of spontaneous breathing, it does not give rise to raised cerebrospinal fluid or intra-ocular pressure, it does not adversely affect renal function, and it can be used quite safely in combination with fentanyl or pentazocine in anaesthetic practice.
mesh_terms: D000328:Adult; D000777:Anesthetics; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D002555:Cerebrospinal Fluid / Q000187:drug effects; D004359:Drug Therapy, Combination; D005260:Female; D005283:Fentanyl; D005445:Flunitrazepam / Q000494:pharmacology*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D007668:Kidney / Q000187:drug effects; D008875:Middle Aged; D010423:Pentazocine
chemical_list: D000777:Anesthetics; D014151:Anti-Anxiety Agents; D005445:Flunitrazepam; D010423:Pentazocine; D005283:Fentanyl