The serological recognition of the human MLC determinants using a modified cytotoxicity technique.
A new approach which presumably recognizes MLC determinants (or at least structures closely linked to MLC and different from the FOUR, AJ and LA series determinants) by serology is described. As the test can be performed within 10 h it could be used to match cadaveric kidney donors for these MLC determinants. Perhaps even more important is the fact that the antibodies detected by this technique could be used to study the immunochemistry of a class of determinants differing from the well known SD determinants.
D000888:Antibodies, Anti-Idiotypic; D001402:B-Lymphocytes / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D005787:Gene Frequency; D008040:Genetic Linkage; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006650:Histocompatibility Testing; D006801:Humans; D007959:Lymphocyte Culture Test, Mixed; D012703:Serotyping
D000888:Antibodies, Anti-Idiotypic; D000939:Epitopes; D006680:HLA Antigens; D006649:Histocompatibility Antigens