[Immunochemical aspects of antigenicity (author's transl)].
A number of chemically definable parameters related to antigenicity are discussed. These include determinant size and density, antigen shape as well as eliciting, inhibiting and tolerogenic capacities of model antigens, notably those of the penicillin allergy model. A kinitic argument for a restricted antibody diversity is presented.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D000917:Antibody Formation; D000937:Antigen-Antibody Reactions; D000941:Antigens / Q000032:analysis; D001666:Binding Sites, Antibody; D004342:Drug Hypersensitivity; D000939:Epitopes; D006241:Haptens; D006801:Humans; D007108:Immune Tolerance; D007120:Immunochemistry; D051379:Mice; D008970:Molecular Weight; D010406:Penicillins / Q000009:adverse effects
D000596:Amino Acids; D000941:Antigens; D000939:Epitopes; D006241:Haptens; D010406:Penicillins
Immunchemische Aspekte der Antigenität