Deposits of immunoglobulins and complement in the dermoepidermal junction of patients with anaphylactoid purpura.
Skin biopsies from 3 patients with anaphylactoid purpura examined by an immunofluorescence technique revealed deposits of immunoglobulins, complement C3, and fibrinogen in the dermo-epidermal junction and in vessel walls of clinically involved as well as uninvolved skin. The deposits in the dermo-epidermal junction are similar to those seen in the skin of patients with systemic lupus erythematosus.
D000368:Aged; D000818:Animals; D001706:Biopsy; D002648:Child; D003176:Complement C3 / Q000378:metabolism*; D003165:Complement System Proteins / Q000378:metabolism*; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D011695:IgA Vasculitis / Q000276:immunology*; D007136:Immunoglobulins / Q000378:metabolism*; D008297:Male; D012867:Skin / Q000276:immunology* / Q000473:pathology
D003176:Complement C3; D007136:Immunoglobulins; D005340:Fibrinogen; D003165:Complement System Proteins