The effect of proctolin on the adenylate and guanylate cyclases in the Locusta brain at various developmental stages.
Proctolin at concentrations 10(-8)-10(-7) M elevated by 40% brain adenylate cyclase activity of adult Locusta migratoria migratoriodes R.F. In moulting individuals, proctolin caused a decrease in brain adenylate cyclase activity, and it proved to be ineffective in the larvae. Proctolin caused only a slight decrease on guanylate cyclase activity of the brain at every developmental stage.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000201:enzymology* / Q000254:growth & development; D004789:Enzyme Activation; D006110:Grasshoppers; D006162:Guanylate Cyclase / Q000378:metabolism*; D007700:Kinetics; D007814:Larva / Q000201:enzymology; D008675:Metamorphosis, Biological; D009479:Neuropeptides; D009842:Oligopeptides / Q000494:pharmacology*
D009479:Neuropeptides; D009842:Oligopeptides; C011536:proctolin; D000262:Adenylyl Cyclases; D006162:Guanylate Cyclase