title: [Pathophysiology and clinical significance of gut hormones].
abstract: The different mode of secretion of the gut hormones (paracrine secretion--somatostatin. endocrine and neurocrine secretion--gastrin, CCK; neurocrine secretion--VIP, substance P), obscures the physiological significance of these hormones. However, the pathophysiological role of autonomous secreted hormones by endocrine tumours, is well established. Gut hormones are used for routine evaluation of gastrointestinal diseases. The therapeutic value of these substances has recently engendered considerable interest.
mesh_terms: D001786:Blood Glucose; D003920:Diabetes Mellitus / Q000628:therapy; D004064:Digestive System / Q000378:metabolism; D004700:Endocrine System Diseases / Q000209:etiology; D005746:Gastric Emptying; D005768:Gastrointestinal Hormones / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007328:Insulin / Q000627:therapeutic use; D009369:Neoplasms; D010437:Peptic Ulcer / Q000517:prevention & control; D010438:Peptic Ulcer Hemorrhage / Q000628:therapy; D012633:Secretin / Q000627:therapeutic use; D013004:Somatostatin / Q000627:therapeutic use
chemical_list: D001786:Blood Glucose; D005768:Gastrointestinal Hormones; D007328:Insulin; D012633:Secretin; D013004:Somatostatin
vernacular_title: Physiologie und klinische Bedeutung gastrointestinal hormone.