Radioimmunoassay of alpha-fetoprotein in the serum of patients with leukemia and malignant melanoma.
A sensitive double antibody radioimmunoassay has been used to measure Alpha-fetoprotein in the serum of healthy subjects, pregnant women and patients with a variety of malignant diseases including leukemia and melanoma. Elevated serum Alpha-fetoprotein levels were found in 2 of 35 patients with leukemia, 2 of 10 with melanoma. All the pregnant women studied had raised levels.
D000328:Adult; D000368:Aged; D000917:Antibody Formation; D001666:Binding Sites, Antibody; D001782:Blood Donors; D005260:Female; D005326:Fetal Proteins / Q000276:immunology*; D006801:Humans; D007938:Leukemia / Q000097:blood*; D008297:Male; D008545:Melanoma / Q000097:blood*; D008875:Middle Aged; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011863:Radioimmunoassay; D012878:Skin Neoplasms / Q000097:blood; D000509:alpha-Fetoproteins / Q000276:immunology*
D005326:Fetal Proteins; D000509:alpha-Fetoproteins