The differences in atrioventricular conduction of premature beats in young and adult goats.
Atrioventricular (AV) conduction was studied in anesthetized, open-chest, 1-35-day-old goats. Atrial, bundle of His, and ventricular bipolar electrograms were recorded, and the functional refractory periods of the AV conduction system and the ventricles were determined. Supraventricular premature excitation invaded the ventricles during their vulnerable period. This AV conduction property is different from that of the adult goat heart; thus, the existence of a lateral accessory bypass tract was investigated. Electrocardiographic leads I, aVF, and V10 revealed no delta waves indicative of ventricular preexcitation. Bundle of His electrograms showed that: (1) bundle of His excitation always preceded the onset of ventricular depolarization, (2) no shortening occurred in the bundle of His to ventricular activation time following early atrial premature beats, and (3) the functional refractory period of the AV node was less than that of the ventricle. The ventricular epicardial excitation sequence indicated no involvement of a lateral bypass tract in the AV conduction of basic or premature beats. Interruption of the bundle of His caused complete AV block. Therefore, no functional lateral accessory bypass tracts are present in the young goat heart, and the AV node and the ventricular specialized conduction system of the young goat are capable of conducting premature atrial excitation to the ventricles within plus or minus 10 msec of the expiration of the ventricular functional refractory period.
D000818:Animals; D000831:Animals, Newborn; D001283:Atrioventricular Node / Q000502:physiology*; D002036:Bundle of His / Q000502:physiology; D005117:Cardiac Complexes, Premature / Q000503:physiopathology; D004558:Electric Stimulation; D004562:Electrocardiography; D004567:Electrodes, Implanted; D004594:Electrophysiology; D006041:Goats / Q000502:physiology*; D006321:Heart / Q000294:innervation; D006329:Heart Conduction System / Q000502:physiology*; D009434:Neural Pathways; D011930:Reaction Time; D014672:Vectorcardiography; D016276:Ventricular Function