The inhibitory effect of bovine rumen fluid on Salmonella typhimurium.
The possible fate of Salmonella typhimurium in the rumen was investigated by monitoring rumen volatile fatty acids (VFA), lactate concentrations and pH over periods which included regular feeding and 48 h starvation. Preparations were made containing 50 per cent rumen fluid from the cow or VFA solutions, and then inoculated with S typhimurium. Viable counts before and after incubation for 24 h at 37 degrees C were compared. Incubation in broths with high concentrations of VFA and low pH resulted in a marked decrease in salmonella numbers, while lower VFA concentrations had little or no inhibitory effect on growth.
D000818:Animals; D001826:Body Fluids / Q000502:physiology; D002417:Cattle / Q000378:metabolism*; D005232:Fatty Acids, Volatile / Q000494:pharmacology; D005260:Female; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D012417:Rumen / Q000378:metabolism*; D012486:Salmonella typhimurium / Q000254:growth & development*
D005232:Fatty Acids, Volatile