Kainic acid lesions of the striatum in rats mimic the spontaneous motor abnormalities of Huntington's Disease.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D003342:Corpus Striatum / Q000187:drug effects*; D004195:Disease Models, Animal; D005968:Glutamate Decarboxylase / Q000378:metabolism; D006816:Huntington Disease / Q000139:chemically induced* / Q000201:enzymology / Q000523:psychology; D007608:Kainic Acid / Q000494:pharmacology*; D008297:Male; D009043:Motor Activity / Q000187:drug effects*; D010868:Pimozide / Q000494:pharmacology; D011759:Pyrrolidines / Q000494:pharmacology*; D051381:Rats; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism
D011759:Pyrrolidines; D010868:Pimozide; D014446:Tyrosine 3-Monooxygenase; D002795:Choline O-Acetyltransferase; D005968:Glutamate Decarboxylase; D007608:Kainic Acid