Serum immunoglobulin E concentrations and radioallergosorbent tests in children with atopic dermatitis.
Serum IgE concentrations and the presence of allergen-specific IgE were determined in a series of 23 children with atopic dermatitis. In this group 83% had significantly elevated serum levels of IgE, 91% had coexistent respiratory allergy, 70% had radioallergosorbent test (RAST) evidence of pollen hypersensitivity, and 43% gave a history and demonstrated a RAST score consistent with milk or egg hypersensitivity. In patients with eczema a significant proportion of the elevated serum IgE appears to be antigen specific.
D000293:Adolescent; D000367:Age Factors; D000485:Allergens; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D003876:Dermatitis, Atopic / Q000097:blood / Q000150:complications / Q000276:immunology*; D000939:Epitopes; D005260:Female; D005512:Food Hypersensitivity / Q000209:etiology / Q000276:immunology*; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications / Q000276:immunology; D007073:Immunoglobulin E / Q000032:analysis*; D007223:Infant; D008297:Male; D011863:Radioimmunoassay; D012130:Respiratory Hypersensitivity / Q000209:etiology / Q000276:immunology*; D012737:Sex Factors; D012882:Skin Tests
D000485:Allergens; D000939:Epitopes; D007073:Immunoglobulin E