[Spread of viral hepatitis in organized children's collectives and the methods for its early diagnosis].
The authors present the results of observations over 407 children aged from 2 months to 16 years from the foci of viral hepatitis in children's collective bodies. During the quarantine a determination was made in children of the glutamic-pyroracemic, glutamic-oxalic transaminases (GPT and GOT, respectively) and of the hepatitis B antigen (HBAg). A necessity of using the enzymatic tests for the purpose of early diagnosis of viral hepatitis was shown, since 84% of the cases developing in the next focus coursed as an unicteric form without any markked clinical signs; HBAg was revealed in 6.1% of the children examined. A complex examination of the personnel and of the persons who came in contact with the patients with viral hepatitis showed the ways of spread of hepatitis B in a collective body; it was found that the viral hepatitis B infection took place both by parenteral and enteral routes. The expediency of active observation over the children, recipients of blood and plasma, with determination in them of the activity of the enzymes and HBAg for early diagnosis of parenteral infection was substantiated. It was also shown that the incidence of the unicteric forms of viral hepatitis in a focus of infection depended not on the periods of gamma-globulin administration but on the age of children who contracted the infection. Thus, the prevalence of the unicteric forms of the disease over the icteric ones in children under 3 years of age was more pronounced than in older children.
D000293:Adolescent; D002648:Child; D002656:Child Day Care Centers; D002673:Child, Hospitalized; D002675:Child, Preschool; D004796:Clinical Enzyme Tests; D006294:Health Resorts; D006506:Hepatitis A / Q000175:diagnosis / Q000276:immunology / Q000635:transmission*; D006509:Hepatitis B / Q000175:diagnosis / Q000276:immunology; D006511:Hepatitis B Antigens / Q000032:analysis; D006801:Humans; D007223:Infant; D009724:Nurseries, Infant; D013997:Time Factors; D065227:Transfusion Reaction; D014586:USSR; D005719:gamma-Globulins / Q000627:therapeutic use
D006511:Hepatitis B Antigens; D005719:gamma-Globulins
Rasprostranenie virusnogo gepatita v organizlovannykh detskikh kollektivakh i metody ranneĭ ego diagnostiki