Effect of sympathetic denervation on chronic cold injuries in rabbit brain. A microangiographical and histological study.
Sympathetic denervation of the brain vessels was performed uni- or bilaterally in 13 adult rabbits, and cortical cold lesions were induced bilaterally 10-18 days afterwards. After a further 4-35 days the vascular and morphological changes in the lesion areas were studied histologically and with angiography. No difference was observed between the denervated and the non-denervated lesion areas. The results are discussed with regard to a proposed functional plasticity of the chronically denervated brain vessels and/or to possible changes in metabolic demands of the brain tissue.
D000792:Angiography; D000818:Animals; D001929:Brain Edema / Q000209:etiology; D001930:Brain Injuries / Q000473:pathology; D002536:Cerebral Arteries / Q000294:innervation*; D002540:Cerebral Cortex / Q000473:pathology*; D003080:Cold Temperature; D008852:Microradiography; D011817:Rabbits; D013194:Staining and Labeling; D013562:Sympathectomy