[Studies of the presence of enzymes in various tissues of swine. 5. Studies of the activity and properties of adenosine triphosphatases in the pancreas].
Studies were conducted into the activities of magnesium-ATPase, sodium-potassium-ATPase, and HCO3-ATPase in homogenates of pancreas of 19 foetuses, with body weights between 340 g and 1,642 g, two piglets, with body weights of 9 kg and 10 kg, and four adult pigs. While general enzyme activity was low during foetal development, highest activies usually were recordable from HCO3-ATPase. High activities were recorded from both the piglets and adult pigs. The highest data, again, were recordable from HCO3-ATPase which is essential to the secretion of HCO3 ions. Maximum activity of magnesium-ATPase was based on an ATP-magnesium ratio of 1:1. HCO3-ATPase was best activated by 25 mM NaHCO3 and exhibited high stability to temperature. The activities of magnesium-ATPase and of HCO3-ATPase were inhibited by 10 mM of Rhodanid. Calcium-ATPase reached its maximum activity in response to 5 mM calcium concentration.
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000375:Aging; D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology; D002118:Calcium / Q000494:pharmacology; D000252:Calcium-Transporting ATPases / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D008274:Magnesium / Q000494:pharmacology; D010042:Ouabain / Q000494:pharmacology; D010179:Pancreas / Q000196:embryology / Q000201:enzymology*; D011190:Potassium Cyanide / Q000494:pharmacology; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism; D013552:Swine / Q000378:metabolism*; D013696:Temperature
D001639:Bicarbonates; D010042:Ouabain; D000251:Adenosine Triphosphatases; D000252:Calcium-Transporting ATPases; D000254:Sodium-Potassium-Exchanging ATPase; D008274:Magnesium; D011190:Potassium Cyanide; D002118:Calcium
Untersuchungen über die Enzymausrüstung verschiedener Gewebe beim Schwein. 5. Mitteilung: Untersuchungen über die Aktivität und einige Eigenschaften der Adenosintriphosphatasen im Pankreas.