title: Characterisation and quantitation of morphine in urine using high-pressure liquid chromatography with fluorescence detection.
abstract: A simple and rapid method for the identification and quantitation of morphine in urine samples is described. The procedure, which involves conversion of the drug a fluorescent product followed by liquid chromatography, is shown to be highly sensitive and specific. Levels down to 0.01 mug/ml of morphine can be quantitatively detected in urine. A large number of drugs have been tested and shown not to interfere.
mesh_terms: D002845:Chromatography; D005453:Fluorescence; D005470:Fluorometry; D006801:Humans; D004091:Hydromorphone; D009020:Morphine / Q000652:urine*; D011312:Pressure; D013050:Spectrometry, Fluorescence
chemical_list: D009020:Morphine; D004091:Hydromorphone