Sickled erythrocytes, hyphema, and secondary glaucoma: VI. The relationship between intracameral blood cells and aqueous humor pH, PO2, and PCO2.
Injection of Hgb SC blood into rabbit anterior chambers resulted in lowering of aqueous humor pH and PO2 and elevation of aqueous humor PCO2. These effects appear to contribute to the sickling of erythrocytes that occurs in aqueous humor.
D000755:Anemia, Sickle Cell / Q000150:complications*; D000818:Animals; D001082:Aqueous Humor / Q000032:analysis*; D002245:Carbon Dioxide / Q000032:analysis; D004913:Erythrocytes, Abnormal; D006451:Hemoglobin, Sickle; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006988:Hyphema / Q000150:complications*; D007267:Injections; D007429:Intraocular Pressure; D010100:Oxygen / Q000032:analysis; D011817:Rabbits; D012805:Sickle Cell Trait / Q000150:complications*
D006451:Hemoglobin, Sickle; D002245:Carbon Dioxide; D010100:Oxygen