Comparison of intracytoplasmic A particles and intracisternal A particles.
Intracytoplasmic A particles and intracisternal A particles are associated with mouse tumors of various types, and both can coexist in the cytoplasm of the same cell. The designation of both as A particles is based on the recognition that they share morphological similarities. A comparison of purified isolates of these two particles reveals that the structural protein profiles are different, but that there is some antigenic cross-reaction as demonstrated by immunodiffusion and complement fixation. This result does not appear to involve the major structural protein of intracisternal A particles, but may reflect the presence of common antigenic determinants located on minor proteins.
D000818:Animals; D003429:Cross Reactions; D003593:Cytoplasm / Q000648:ultrastructure*; D004721:Endoplasmic Reticulum / Q000648:ultrastructure*; D000939:Epitopes; D007106:Immune Sera; D007181:Inclusion Bodies, Viral / Q000032:analysis / Q000648:ultrastructure; D007984:Leydig Cell Tumor / Q000276:immunology / Q000473:pathology*; D008325:Mammary Neoplasms, Experimental / Q000276:immunology / Q000473:pathology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009374:Neoplasms, Experimental / Q000473:pathology; D010954:Plasmacytoma / Q000276:immunology / Q000473:pathology*; D011817:Rabbits / Q000276:immunology; D014764:Viral Proteins / Q000032:analysis
D000939:Epitopes; D007106:Immune Sera; D014764:Viral Proteins