title: [Bone marrow insufficiency and hemangioendothelioma of the liver after thorotrast application: Late effects of thorotrast (thorium dioxide) in man (author's transl)].
abstract: The report details with the late effects following administration of thorotrast in two patients: multicentre metastating hemangioendothelioma of the liver respective bone marrow insufficiency developed after application of thorotrast 34 respective 36 years ago. The clinical and autoptical findings are described and attention is drawn to the relevance of this disease at present time.
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism; D001855:Bone Marrow Diseases / Q000209:etiology*; D006390:Hemangioendothelioma / Q000209:etiology*; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries; D013911:Thorium Dioxide / Q000009:adverse effects*; D013997:Time Factors; D005723:gamma-Glutamyltransferase / Q000378:metabolism
chemical_list: D013911:Thorium Dioxide; D005723:gamma-Glutamyltransferase; D000469:Alkaline Phosphatase
vernacular_title: Panmyelopathie und metastasierendes Hämangioendotheliom der Leber nach Thorotrastapplikation. Ein kasuistischer Beitrag zu den Spätfolgen nach Thorotrastanwendung.