[Fragmentation of gamma globulin preparations manufactured in the USSR].
Gamma-globulin preparations prepared by the alcoholic method from the placental and abortion sera were split during storage under the effect of proteases contained in them; fragments with a molecular weight of 50 000 and 60 000 were formed. The most intensive splitting was seen in the preparations obtained from the precipitates of B placental and abortive sera. Some delay in the gamma-globulin fragmentation could be reached by addition to protease inhibitors--epsilon-aminocapronic acid or cyclocapron.
D000614:Aminocaproates / Q000494:pharmacology; D002855:Chromatography, Thin Layer; D004355:Drug Stability; D004356:Drug Storage; D011480:Protease Inhibitors; D014586:USSR; D005719:gamma-Globulins / Q000032:analysis
D000614:Aminocaproates; D011480:Protease Inhibitors; D005719:gamma-Globulins
Issledovanie fragmentatsii preparatov gamma-globulina, vypuskaemykh v SSSR