title: Selective alteration in high affinity agonist binding: a mechanism of beta-adrenergic receptor desensitization.
mesh_terms: D000262:Adenylyl Cyclases / Q000097:blood; D000318:Adrenergic beta-Agonists / Q000378:metabolism*; D000319:Adrenergic beta-Antagonists / Q000097:blood; D000818:Animals; D001001:Anura; D001667:Binding, Competitive; D004082:Dihydroalprenolol / Q000097:blood; D004910:Erythrocyte Membrane / Q000378:metabolism; D006150:Guanine Nucleotides / Q000494:pharmacology; D066298:In Vitro Techniques; D007202:Indicators and Reagents / Q000494:pharmacology; D007545:Isoproterenol / Q000097:blood; D011894:Rana pipiens; D011941:Receptors, Adrenergic / Q000378:metabolism*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000378:metabolism*; D013997:Time Factors
chemical_list: D000318:Adrenergic beta-Agonists; D000319:Adrenergic beta-Antagonists; D006150:Guanine Nucleotides; D007202:Indicators and Reagents; D011941:Receptors, Adrenergic; D011943:Receptors, Adrenergic, beta; D004082:Dihydroalprenolol; D000262:Adenylyl Cyclases; D007545:Isoproterenol