Low HL-A2 frequency and periodontitis.
The frequency of HL-A2 was significantly low (21%) in patients with periodontitis when compared to controls who were free of periodontal disease (61%). The effect was most pronounced in females in whom HL-A2 was present in 12.5% (2 out of 16). This finding suggests that genes controlling susceptibility to microbial agents may be linked to the HL-A LOCUS.
D000939:Epitopes; D005260:Female; D008040:Genetic Linkage; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006801:Humans; D008297:Male; D010518:Periodontitis / Q000276:immunology*; D012737:Sex Factors
D000939:Epitopes; D006680:HLA Antigens; D006649:Histocompatibility Antigens