[Influenza immunization, clinical results and serological tests (author's transl)].
207 patients of a geriatric department were immunized against influenza with either tween-ether-split-vaccine or subunit-vaccine in a double blind study. For 6 months the following data were daily registered: rest in bed, fever over 38,5 degrees C, rhinitis, laryngopharingitis, bronchitis, pneumonia, enteritis, medication with antibiotics or chemotherapeutics. In cases with fever over 38,5 degrees C blood tests were taken for serological examination. The immune response against influenza A was excellent in both groups, the titer was higher in the subunit group, only one patient showed influenza infection. The immune response against the type B Hongkong was not satisfactory in both groups. The clinical data showed a significant lower incidence of rhinitis, laryngopharingitis and bronchitis in the group immunized with the tween-ether-split-vaccine. This effect was more distinct within the first 3 months after the immunization than within the second 3 months.
D000368:Aged; D004311:Double-Blind Method; D006801:Humans; D007252:Influenza Vaccines / Q000276:immunology*; D007251:Influenza, Human / Q000276:immunology / Q000517:prevention & control*; D014611:Vaccination
D007252:Influenza Vaccines
Klinische und serologische Untersuchungen zur Wirkung der Influenzaimpfung.