Role of calcium dependent regulator protein (CDR) in inhibition of 3',5'-c AMP-phosphodiesterase by influenza virus. I. Isolation and purification of CDR and CDR-dependent 3',5'-c' AMP-phosphodiesterase from chick embryos.
Calcium-dependent regulator protein (CDR) and CDR-dependent 3',5'-c AMP-phosphodiesterase were isolated and partially purified from 12-day chick embryos. Some basic properties of the preparations obtained were described. Native (infectious) but not noninfectious (heat-inactivated) influenza virus in the presence of CDR and ATP reduced the activity of CDR-dependent phosphodiesterase.
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors / Q000302:isolation & purification*; D000818:Animals; D002135:Calcium-Binding Proteins / Q000302:isolation & purification*; D002147:Calmodulin / Q000302:isolation & purification*; D002642:Chick Embryo / Q000032:analysis*; D009980:Influenza A virus / Q000502:physiology*
D002135:Calcium-Binding Proteins; D002147:Calmodulin; D015105:3',5'-Cyclic-AMP Phosphodiesterases