Diethylpyrocarbonate interferes with lipid-protein interaction and glucose transport in the human red cell membrane.
Diethylpyrocarbonate largely diminished both discontinuities in red cell glucose transport and also in red cell membrane ANS fluorescence at about 17--20 degrees C.
D001692:Biological Transport / Q000187:drug effects; D001786:Blood Glucose / Q000378:metabolism*; D001798:Blood Proteins / Q000378:metabolism*; D004047:Diethyl Pyrocarbonate / Q000494:pharmacology*; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism*; D005561:Formates / Q000494:pharmacology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008563:Membrane Lipids / Q000097:blood*; D008565:Membrane Proteins / Q000097:blood*; D013050:Spectrometry, Fluorescence; D013696:Temperature; D013997:Time Factors
D001786:Blood Glucose; D001798:Blood Proteins; D005561:Formates; D008563:Membrane Lipids; D008565:Membrane Proteins; D004047:Diethyl Pyrocarbonate