Lack of effect of neurotransmitters on cyclic AMP phosphodiesterase activity in an insect CNS.
The inhibition of cyclic nucleotide phosphodiesterase from the nerve cord of Manduca sexta was studied using theophylline as a model compound. 11 putative neurotransmitters had no effect on enzyme activity.
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000378:metabolism*; D000818:Animals; D007700:Kinetics; D007915:Lepidoptera / Q000201:enzymology*; D009420:Nervous System / Q000201:enzymology*; D018377:Neurotransmitter Agents / Q000494:pharmacology*; D013806:Theophylline / Q000494:pharmacology
D018377:Neurotransmitter Agents; D013806:Theophylline; D015105:3',5'-Cyclic-AMP Phosphodiesterases