title: [Alpha-fetoprotein: its significance in the monitoring of "at risk" pregnancies (author's transl)].
abstract: Having plotted a curve showing the normal values of Alpha-Foeto-protein (AFP) concentration in maternal serum and amniotic fluid, its significance in the monitoring of "at risk" pregnancies was examined and critically judged in the light of statements found in the literature. According to the results gained AFP determination in maternal serum or amniotic fluid can only be used with reservation as a monitoring test in "at risk" pregnancies. In particular in Rhesus Incompatibility it was impossible to establish the degree of foetal Haemolysis or to determine the best time for premature induction. In addition an intra-uterine death could not be predicted with certainty.
mesh_terms: D000029:Abortion, Legal; D000033:Abortion, Threatened / Q000097:blood / Q000175:diagnosis; D000653:Amniotic Fluid / Q000032:analysis*; D001787:Blood Group Incompatibility / Q000097:blood; D005260:Female; D005313:Fetal Death / Q000175:diagnosis; D005315:Fetal Diseases / Q000175:diagnosis; D005326:Fetal Proteins / Q000032:analysis*; D006801:Humans; D006973:Hypertension / Q000097:blood; D011225:Pre-Eclampsia / Q000097:blood; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011254:Pregnancy in Diabetics / Q000097:blood; D011295:Prenatal Care; D011296:Prenatal Diagnosis; D011379:Prognosis; D012204:Rh-Hr Blood-Group System; D000509:alpha-Fetoproteins / Q000032:analysis*
chemical_list: D005326:Fetal Proteins; D012204:Rh-Hr Blood-Group System; D000509:alpha-Fetoproteins
vernacular_title: Alpha-Fetoprotein: Bedeutung in der Uberwachung von Risiko-Schwangerschaften