[Peritoneal vascular injuries induced by gaseous oxygen].
When introduced as a gas into the abdominal cavity of the rat, oxygen above the initial concentration of 10 % provokes vasodilatation, perivascular oedematous infiltrations and fluid formation. These lesions are entirely reversible. Antihistaminics (promethazine and mepyramine 2 mg/100 g completely inhibit vascular lesions.
D000818:Animals; D001201:Ascites / Q000139:chemically induced; D001202:Ascitic Fluid / Q000166:cytology; D002199:Capillary Permeability / Q000187:drug effects; D004487:Edema / Q000139:chemically induced; D005260:Female; D005740:Gases; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D008297:Male; D008407:Mast Cells / Q000187:drug effects / Q000378:metabolism; D010100:Oxygen / Q000009:adverse effects*; D010537:Peritoneum / Q000098:blood supply*; D051381:Rats; D014664:Vasodilation / Q000187:drug effects
D005740:Gases; D006634:Histamine H1 Antagonists; D010100:Oxygen
Lésions vasculaires péritonéales provoquées par l'oxygène gazeux.