[Oxidative phoshporylation, proton exchange and volume changes in hepatocyte mitochondria under the effect of exogenous succinate].
Long use of exogenous succinate causes changes in hepatocytes bioenergetic functions in guinea pigs. The character of cation is of essential significance in this situation: sodium succinate produces a moderate stimulating effect, potassium succinate evokes a distinct energizing influence.
D000818:Animals; D006168:Guinea Pigs; D006863:Hydrogen-Ion Concentration; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D008933:Mitochondrial Swelling / Q000187:drug effects; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D011188:Potassium / Q000494:pharmacology; D012964:Sodium / Q000494:pharmacology; D013386:Succinates / Q000494:pharmacology*
D013386:Succinates; D012964:Sodium; D011188:Potassium
Okislitel'noe fosforilirovanie, obmen protonov i ob'emnye izmeneniia mitokhondriĭ gepatotsitov pri vozdeĭstvii ekzogennogo suktsinata.