title: An evaluation of 12 methods for the demonstration of penicillinase.
abstract: Twelve methods for the demonstration of bacterial penicillinase production by strains of Haemophilus influenzae and Staphylococcus aureus are compared, and their suitability for routine clinical laboratory use is evaluated. The acidometric agar plate method is recommended.
mesh_terms: D001431:Bacteriological Techniques; D002511:Cephalosporins; D005069:Evaluation Studies as Topic; D006193:Haemophilus influenzae / Q000201:enzymology*; D006863:Hydrogen-Ion Concentration; D010405:Penicillinase / Q000032:analysis*; D013211:Staphylococcus aureus / Q000201:enzymology*; D001618:beta-Lactamases / Q000032:analysis*
chemical_list: D002511:Cephalosporins; D010405:Penicillinase; D001618:beta-Lactamases