title: [The treatment with tiparide of the agitation and aggressivity of oligophrenic patients (author's transl)].
abstract: Tiapride, which is an original medication for the treatment of agitation and psychomotor excitation, was studied in mentally retarded patients; 9 severe and 3 moderate, suffering from bouts of agitation and excitation and aged from 18 to 40 years. The dosage was 4 ampoules (400 mg) daily by IM injection in acute agitation (2 cases), 6 tablets (600 mg) daily in moderately severe cases, and 4 tablets (400 mg) daily in milder cases (4). Very good results were obtained in 3 patients, and good results in 6 others, while no effect was noted in 3 patients (in spite of a reduction in dosage of the other medications). Tolerance was excellent in all cases. Tiapride should fill the therapeutic gap which exists today in the treatment of the agitation and aggressivity of oligophrenia.
mesh_terms: D000293:Adolescent; D000328:Adult; D000374:Aggression / Q000187:drug effects*; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001549:Benzamides / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D008297:Male; D011595:Psychomotor Agitation / Q000188:drug therapy* / Q000209:etiology
chemical_list: D014150:Antipsychotic Agents; D001549:Benzamides
vernacular_title: Essai de traitement de l'agitation et de l'agressivité de l'oligophréne par le tiapride.