The use of IgM antibody responses in the diagnosis of primary infections to measles, rubella, mumps, and M. Parainfluenzae viruses.
One-hundred and twenty-seven sera were tested to determine whether a primary infection could be identified by a determination of the class of antibody (IgM) detected in serum collected in the period after a viral infection. Serum was collected from patients with a history of measles (18 cases), rubella (24 cases), mumps (12 cases), and M. parainfluenzae type 3 infections (9 cases). The results of the serological assays are compared with clinical observations and the limitations of the methods under consideration are discussed.
D000914:Antibodies, Viral / Q000032:analysis*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D005779:Immunodiffusion; D007075:Immunoglobulin M / Q000032:analysis*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008457:Measles / Q000175:diagnosis; D008459:Measles virus / Q000276:immunology; D009107:Mumps / Q000175:diagnosis; D009109:Mumps virus / Q000276:immunology; D010224:Parainfluenza Virus 3, Human / Q000276:immunology; D018184:Paramyxoviridae Infections / Q000175:diagnosis; D011247:Pregnancy; D012409:Rubella / Q000175:diagnosis; D012412:Rubella virus / Q000276:immunology; D014777:Virus Diseases / Q000175:diagnosis*
D000914:Antibodies, Viral; D007075:Immunoglobulin M