title: Choline acetyltransferase activity in human blood and its diurnal oscillation--an artifact?
abstract: Diurnal oscillation of choline acetyltransferase (ChAT)-like activity in human blood has recently been reported in the literature. From studies on the pH-optimum of acetylcholine synthesizing activity in human blood we suggest, however, that this activity is only partly related to ChAT, and that the diurnal oscillation observed might be an artifact resulting from the analytical procedure.
mesh_terms: D000109:Acetylcholine / Q000096:biosynthesis; D000328:Adult; D002795:Choline O-Acetyltransferase / Q000097:blood*; D002940:Circadian Rhythm; D003951:Diagnostic Errors; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male
chemical_list: D002795:Choline O-Acetyltransferase; D000109:Acetylcholine