title: [The influence of hydroxyethyl starch on postoperative alterations of blood coagulation (author's transl)].
abstract: The influence of hydroxyethyl starch (HES) on postoperative hypercoagulaemia was examined in a double blind study. One group of 10 patients received 500 ml HES during surgery and on the following three days. A comparable group received the same amount of isotonic saline solution. In some respects, hypercoagulaemia was significantly diminished in the HES-group. The diminution could, however, be mainly explained by the diluting effect of the plasma expander.
mesh_terms: D000328:Adult; D000368:Aged; D001777:Blood Coagulation / Q000187:drug effects*; D001778:Blood Coagulation Disorders / Q000188:drug therapy; D001780:Blood Coagulation Tests; D001810:Blood Volume; D005169:Factor VIII; D005260:Female; D005340:Fibrinogen; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010919:Placebos; D011183:Postoperative Complications / Q000097:blood*; D013213:Starch / Q000031:analogs & derivatives*; D013916:Thrombelastography
chemical_list: D006895:Hydroxyethyl Starch Derivatives; D010919:Placebos; D005169:Factor VIII; D005340:Fibrinogen; D013213:Starch
vernacular_title: Zur Beeinflussung postoperativer Anderungen der Blutgerinnung durch Hydroxyäthylstärke