The tyramines: are they involved in the psychoses?
On the evidence that the administration of some antipsychotic drugs and d-amphetamine, separately and in combination, induced changes in the concentration of striatal p- and m-tyramine, it is proposed that the tyramines may possess a role in neural function. This function could be as neurotransmitters in specific neuronal systems or as synaptic activators.
D015102:3,4-Dihydroxyphenylacetic Acid / Q000378:metabolism; D000818:Animals; D002421:Caudate Nucleus / Q000378:metabolism; D002746:Chlorpromazine / Q000494:pharmacology; D003913:Dextroamphetamine / Q000494:pharmacology; D006801:Humans; D008297:Male; D051379:Mice; D010640:Phenothiazines / Q000494:pharmacology; D011618:Psychotic Disorders / Q000378:metabolism*; D011699:Putamen / Q000378:metabolism; D013881:Thioridazine / Q000494:pharmacology; D014439:Tyramine / Q000378:metabolism*
D010640:Phenothiazines; D015102:3,4-Dihydroxyphenylacetic Acid; D013881:Thioridazine; D003913:Dextroamphetamine; D002746:Chlorpromazine; D014439:Tyramine