title: [Researches on some properties of inhibitory substances produced by strains of "N. meningitidis" (author's transl)].
abstract: Some properties of three inhibitory substances produced by as many strains of N. meningitidis have been studied. All these substances appeared to be completely destroyed by proteolytic enzymes (trypsin and pronase) and to be very heat-stable; they were insensitive to ultraviolet light and they were stable pH 2-10; filtration through filters of different porosity (Seitz, Berkefeld, millipore membranes) resulted in loss of the inhibitory effect constantly. On the basis of these results and on their specific action specific action, it is possible to class these substances among bacteriocins ("meningocins") at low molecular weight.
mesh_terms: D001430:Bacteriocins / Q000032:analysis* / Q000096:biosynthesis / Q000494:pharmacology; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D008970:Molecular Weight; D009345:Neisseria meningitidis / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000494:pharmacology; D014466:Ultraviolet Rays
chemical_list: D001430:Bacteriocins; D010447:Peptide Hydrolases
vernacular_title: Ricerche su alcune caratteristiche di sostanze ad attività inibente prodotte da stipiti di "N. meningitidis".