Thyroid function in patients in clinical remission after medical treatment of thyrotoxicosis.
This paper described the changes in the levels of serum triiodothyronine, serum thyroxine,serum thyrotrophin and other indices of thyroid function between 2-5 y after completion of antithyroid drug therapy in 35 patients who were euthyroid on clinical criteria. There was a small but significant elevation of the mean triiodothyronine and thyroxine levels with a relative hypersecretion of Triiodothyronine. No correlation was found between the levels of either thyroid hormone measured or their ratio and the radioiodine uptakes and clearance rate, the plasma inorganic iodine level, the absolute iodine uptake or the serum TSH level. There was no case of clinical hypothyroidism but in one patient the TSH level was at the upper limit of the nrmal range and an exaggerated TSH response to TRH was found.
D000328:Adult; D000368:Aged; D002231:Carbimazole / Q000627:therapeutic use; D003276:Contraceptives, Oral / Q000494:pharmacology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy*; D007037:Hypothyroidism / Q000188:drug therapy; D007455:Iodine / Q000097:blood; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D012075:Remission, Spontaneous; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000502:physiology*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood
D003276:Contraceptives, Oral; D014284:Triiodothyronine; D002231:Carbimazole; D013972:Thyrotropin; D007455:Iodine; D013974:Thyroxine