title: Incidence of insulin-dependent diabetes in the first sixteen years of life.
abstract: The incidence of insulin-dependent diabetes in the first 16 years of life in a nationally representative sample was 1-42 per 1000 population. This incidence is larger than that found in previous studies of diabetes in comparable age-groups and suggests an overall increase in incidence in this country. 23% of the diabetics had a history of diabetes in a first-degree relative, which is higher than reported previously. There was no evidence to suggest any association between prenatal and postnatal infections and diabetes.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001991:Bronchitis; D002648:Child; D002675:Child, Preschool; D003920:Diabetes Mellitus / Q000235:genetics; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D007251:Influenza, Human; D007328:Insulin / Q000627:therapeutic use; D008137:Longitudinal Studies; D008297:Male; D008431:Maternal-Fetal Exchange; D008457:Measles / Q000150:complications; D009107:Mumps / Q000150:complications; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012744:Sex Ratio; D006113:United Kingdom
chemical_list: D007328:Insulin