Reduced lectin stimulation of lymphocytes from magnesium-deficient rats.
Spleen cells and thymocytes from Mg-deficient rats, fed a Mg-deficient diet for 10--13 weeks, incorporate [3H]thymidine at half the rate of normal cells. The cells from Mg-deficient rats are less stimulated by lectins than those from normal animals. These effects correspond to the reduced content of gamma-globulins in serum in Mg deficiency. They are caused by the altered electrolyte content of the Mg-deficient cells.
D000818:Animals; D004247:DNA / Q000096:biosynthesis; D037102:Lectins; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D008274:Magnesium / Q000494:pharmacology; D008275:Magnesium Deficiency; D051381:Rats; D013936:Thymidine / Q000378:metabolism; D005719:gamma-Globulins / Q000378:metabolism
D037102:Lectins; D005719:gamma-Globulins; D004247:DNA; D008274:Magnesium; D013936:Thymidine