title: T- and B-cell surface markers on rabbit lymphocytes.
abstract: Rabbit thymus, appendix, blood and lymph nodes were characterized using immunological tests: rosette-forming ability with homologous or heterologous red blood cells, surface immunoglobulins, analytical cell-electrophoresis, cell refringency and in vitro mitogen responsiveness. The experiments were conducted on normal rabbits and cyclophosphamide-treated rabbits. Moreover, we tried to separate slow and high mobility cells by free-flow electrophoresis into fractions. These experiments suggest that rabbit lymphocyte behaviour is exceptional among mammals in that the majority of their lymphocytes appeared as B cells and that, in comparison with mouse and man, the proportions of these cells are inversed.
mesh_terms: D000818:Animals; D001065:Appendix / Q000166:cytology / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology; D003520:Cyclophosphamide / Q000494:pharmacology; D004586:Electrophoresis; D000939:Epitopes; D008198:Lymph Nodes / Q000166:cytology / Q000276:immunology; D011817:Rabbits; D011947:Receptors, Antigen, B-Cell; D013499:Surface Properties; D013601:T-Lymphocytes / Q000276:immunology; D013950:Thymus Gland / Q000166:cytology / Q000276:immunology
chemical_list: D000939:Epitopes; D011947:Receptors, Antigen, B-Cell; D003520:Cyclophosphamide