Antifibrinolytic therapy of subarachnoid hemorrhage by intrathecal administration of p-aminomethylbenzoic acid.
In patients suffering from subarachnoid hemorrhage (SAH), intrathecal administration of p-aminomethylbenzoic acid (PAMBA) was found to produce hemostatically effective concentrations of the antifibrinolytic agent in the cerebrospinal fluid (CSF). The early clinical findings speak in favor of this mode of administration.
D010129:4-Aminobenzoic Acid / Q000008:administration & dosage*; D062365:Aminobenzoates / Q000008:administration & dosage*; D000933:Antifibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D007278:Injections, Spinal; D013345:Subarachnoid Hemorrhage / Q000188:drug therapy*; D062366:para-Aminobenzoates
D062365:Aminobenzoates; D000933:Antifibrinolytic Agents; D062366:para-Aminobenzoates; C015668:4-aminomethylbenzoic acid; D010129:4-Aminobenzoic Acid