[Virus-like particles in the sera of patients with viral hepatitis and donors with antigenemia].
Isopicnic centrifugation in cesium chloride gradient produces sufficiently homogeneous fractions of large (42--45 nm) and small (20--22 nm) particles detectable in sera from patients with viral hepatitis and donors with antigenemia. In addition to morphological criteria, differences between these particles were indicated by a greater buoyant density (1.24 g/cm3), higher sensitivity to lower pH values and a lower resistance between. No antigenic determinats inherent in small particles could be found in large particles.
D002500:Centrifugation, Isopycnic; D000939:Epitopes; D006509:Hepatitis B / Q000097:blood* / Q000382:microbiology; D006514:Hepatitis B Surface Antigens / Q000302:isolation & purification / Q000648:ultrastructure*; D006801:Humans
D000939:Epitopes; D006514:Hepatitis B Surface Antigens
Virusopodobnye chastitsy v syvorotkakh bol'nykh virusnym gepatitom i donorov s antigenemieĭ.