title: [Effect of streptovaricin on the multiplication of L line cells].
abstract: An inhibitor of the reverse trascriptase-streptovaricin in a dose of 4 mkg/ml would induce an increase of the DNA amount in L cell nuclei, while its dosage of 8 mkg/ml decrease the amount of DNA, resulting in the differentiation of some population cells. Streptovaricin inhibited the L cell multiplication, rendering no significant effect on that of normal fibroblasts of C3H mice culture.
mesh_terms: D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002467:Cell Nucleus / Q000187:drug effects; D002478:Cells, Cultured; D004247:DNA / Q000032:analysis; D004305:Dose-Response Relationship, Drug; D007739:L Cells / Q000187:drug effects*; D051379:Mice; D008809:Mice, Inbred C3H; D018894:Reverse Transcriptase Inhibitors; D013310:Streptovaricin / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D018894:Reverse Transcriptase Inhibitors; D013310:Streptovaricin; D004247:DNA
vernacular_title: O vliianii streptovaritsima na razmnozhenie kletok linii L.