Virus-like particles associated with the mitochondria of ethidium bromide treated transformed cells.
A cell line resistant to ethidium bromide has been developed from baby hamster kidney cells transformed by Rous sarcoma virus. The parental cells are normally non-producers but the resistant cell line appears to produce virus-like particles that are associated with the mitochondria as visualized by electron microscopy and determined biochemically.
D001358:Avian Sarcoma Viruses; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002472:Cell Transformation, Viral; D004996:Ethidium / Q000494:pharmacology*; D008928:Mitochondria / Q000201:enzymology / Q000382:microbiology*; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D013347:Subcellular Fractions; D014779:Virus Replication / Q000187:drug effects; D014780:Viruses / Q000187:drug effects* / Q000254:growth & development / Q000648:ultrastructure
D012194:RNA-Directed DNA Polymerase; D004996:Ethidium