[Relationship between digital necrosis of the upper limbs and malignant conditions (author's transl)].
The authors report six new cases of necrosis of the fingers occurring during the course of a malignant condition. None of the patient was suffering from any other disease which could explain the digital necrosis. They discuss the mechanism of the relationship between the two conditions : blood hyperviscosity, thrombocytosis, polycythaemia, cryoglobulin and the production of immune complexes. The particular role of bleomycin is mentioned. The possibility of a true paraneoplastic syndrome is suggested.
D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex; D001761:Bleomycin / Q000009:adverse effects; D001809:Blood Viscosity; D003450:Cryoglobulins; D005260:Female; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis / Q000209:etiology*; D009369:Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D011086:Polycythemia / Q000150:complications; D013922:Thrombocytosis / Q000150:complications
D000936:Antigen-Antibody Complex; D003450:Cryoglobulins; D001761:Bleomycin
Rapports entre nécroses digitales du membre supérieur et affections malignes.