[Basic behavior and behavior after stimulation of inflammatory cellular response, leukocytary chemotaxis and phagocytosis in aged subjects with depression of cellular immunity].
A larger group of 70--75 years aged subjects was studied by means of various cutaneous tests, by E-rosette formation and by blastogenic response and 18 people showing a depressed cellular immunity were selected. These subjects and a similar control group with normal C.M.I. were further investigated in various condition of stimulation for cellular response in inflammation, chemotaxis, phagocytic activity and polysaccharide content in the granulocyte citoplasm. In general the former activity was not depressed, chemotaxis and phagocytic values were deficient, polysaccharide content appeared the same in the normal (control) and in the immune deficient group.
D000367:Age Factors; D000368:Aged; D000917:Antibody Formation; D002633:Chemotaxis / Q000187:drug effects*; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007249:Inflammation / Q000276:immunology*; D007542:Inosine Pranobex / Q000494:pharmacology; D008875:Middle Aged; D009580:Nitroblue Tetrazolium; D010587:Phagocytosis / Q000187:drug effects; D012397:Rosette Formation; D013268:Stimulation, Chemical
D009580:Nitroblue Tetrazolium; D007542:Inosine Pranobex
Comportamento basale e dopo stimolo della risposta cellulare infiammatoria, della chemiotassi leucocitaria e della fagocitosi in soggetti anziani con depressione della immunità cellulare.