[The quantitative detection of estrogens and antithyroid drugs by thin-layer and high performance thin-layer chromatography in animal tissue (author's transl)].
Methods of thin-layer chromatography (TLC) and high-performance thin-layer chromatography (HPTLC) were developed for the determination of estrogens and antithyroid drugs in extracts of animal tissues. TLC proved to be suitable for quantities in the range of 200-2000 ng, with a detection limit of 50-200 ng, HPTLC in the range of 10-200 ng, showing calibration curves of good linearity even in extracts. By HPTLC better detection limits, better separation and faster ascending could be achieved than by TLC.
D000818:Animals; D013956:Antithyroid Agents / Q000032:analysis* / Q000097:blood; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002855:Chromatography, Thin Layer / Q000379:methods; D004967:Estrogens / Q000032:analysis* / Q000097:blood; D005069:Evaluation Studies as Topic; D008832:Microchemistry; D009132:Muscles / Q000032:analysis; D013961:Thyroid Gland / Q000032:analysis
D013956:Antithyroid Agents; D004967:Estrogens
Der quantitative Nachweis von Ostrogenen und Thyreostatika mittels Dünnschichtchromatographie und Hochleistungs-dünnschichtchromatographie in tierischen Substraten