[About the heterogeneity of the murine oncornavirus group-specific antigen gs-1 (author's transl)].
In isoelectric focusing of twofold gradienpturified and Tween 80-ether disrupted RLV the groupspecific antigen (gs-1) was found in 3 pH-zones (4,45-5,5; 5,65-6,0; 6,45-6,6). For the gs-1 from plasma und spleen cells of leukemic mice was shown heterogeneity by several methods: 1. Gs-1 from plasma showed in isoelectric focusing a scattering along the whole elution profile. 2. Agarimmunoelectrophoresis resulted in a longer precipitationline for gs-1 from plasma in comparison with gs-1 from spleen cells. 3. Polyacrylamidgelelectrophoresis with following immunodiffusion made evident the particularly discrete character of this heterogeneity: gs-1 from both materials were found in two main zones.
D000818:Animals; D000917:Antibody Formation; D015478:Antigens, Heterophile; D000951:Antigens, Neoplasm / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis; D000939:Epitopes; D005779:Immunodiffusion; D007525:Isoelectric Focusing; D007942:Leukemia, Experimental / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D009858:Oncogenic Viruses / Q000276:immunology*
D015478:Antigens, Heterophile; D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D000939:Epitopes
Uber die Heterogenität des gruppenspezifischen Antigens (gs-1) der murinen Oncornaviren