[Role of quaternary structure in the antigenic specificity of amino acid derivatives of hemoglobin].
Immunochemical properties of isolated alpha- and beta-chains of aminoenanthyl- and phenylalanyl-hemoglobins were studied by fixation of the complement as compared with the corresponding chains of the native hemoglobin. In spite of the immunochemical differences between Phe-Hb and hemoglobin, the complement fixation ability was shown to be the same in Phe-Hb, AE-Hb and hemoglobin; this phenomenon suggests that formation of the antigenic determinant in Phe-Hb occurs at the level of quaternary structure.
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002682:Chinchilla / Q000276:immunology; D003168:Complement Fixation Tests; D000939:Epitopes; D006454:Hemoglobins / Q000276:immunology*; D006801:Humans
D000939:Epitopes; D006454:Hemoglobins
Znachenie chetvertichnoĭ struktury v antigennoĭ spetsifichnosti aminokislotnykh proizvodnykh gemoglobina.