title: Effect of x-irradiation of recipients on in vivo neutralization of syngeneic tumors by spleen cells nonspecificially immunized with allogeneic tumors.
abstract: Spleen cells from WKA rats immunized with allogeneic Donryu tumor (AH66), when examined by the Winn test, inhibited lethal growth of admixed antigenically unrelated syngeneic tumor (KMT-17) only when a mixture of spleen cells and tumor cells was injected into pre-irradiated recipients. On the other hand, spleen cells specificially sensitized to KMT-17 inhibited growth of admixed KMT-17 cells either in irradiated or non-irradiated rats.
mesh_terms: D000818:Animals; D000939:Epitopes; D007114:Immunization; D008114:Liver Neoplasms, Experimental / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D009368:Neoplasm Transplantation; D011830:Radiation Effects; D051381:Rats; D012513:Sarcoma, Experimental / Q000276:immunology* / Q000532:radiotherapy; D013154:Spleen / Q000276:immunology; D014185:Transplantation, Isogeneic
chemical_list: D000939:Epitopes