title: Dependence on chlormethiazole and effects of its withdrawal.
abstract: Five cases of physical dependence on chlormethiazole are reported. Because sudden withdrawal may precipitate an acute "organic psychosis", chlormethiazole should only be used in hospitals and, even then, only for a maximum of 9 days.
mesh_terms: D000208:Acute Disease; D000368:Aged; D002719:Chlormethiazole / Q000008:administration & dosage; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000209:etiology / Q000517:prevention & control; D013375:Substance Withdrawal Syndrome / Q000517:prevention & control*; D019966:Substance-Related Disorders; D013997:Time Factors
chemical_list: D002719:Chlormethiazole