title: Effect of potassium isobutyrate on absorption of immunoglobulins from colostrum by calves.
abstract: Calves received either colostrum with 2.83 meq potassium isobutyrate per gram of gamma-globulin or colostrum with distilled water within 1 h after birth. Blood samples were taken at intervals during the first 72 h for determination of concentrations of gamma-globulin, immunoglobulin IgG and IgM. Calves fed colostrum with distilled water attained higher concentrations in serum of total gamma-globulin, immunolgobulin IgG and IgM. Holstein calves were more efficient than Ayrshire calves in absorbing total gamma-globulin, but differences between breeds were not significant for specific immunoglobulins. Efficiency of gamma-globulin absorption within 24 h was 35.7% for control calves and 24.7% for calves fed colostrum plus potassium isobutyrate. Potassium isobutyrate had a depressing effect on absorption of immunoglobulins by calves.
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000276:immunology / Q000378:metabolism*; D002087:Butyrates / Q000494:pharmacology*; D002417:Cattle / Q000276:immunology / Q000378:metabolism*; D003126:Colostrum / Q000276:immunology*; D007074:Immunoglobulin G / Q000378:metabolism; D007075:Immunoglobulin M / Q000378:metabolism; D007136:Immunoglobulins / Q000378:metabolism*; D007408:Intestinal Absorption; D011188:Potassium / Q000494:pharmacology*; D005719:gamma-Globulins / Q000032:analysis
chemical_list: D002087:Butyrates; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D005719:gamma-Globulins; D011188:Potassium