The inhibition of arginase from the hepatopancreas of a terrestrial snail by amino acids.
The effects of L-amino acids on arginase from the hepatopancreas of the snail Ariophanta (=Cryptozona) ligulata were studied. This enzyme was inhibited by ornithine, valine, lysine, leucine, isoleucine, proline and threonine. The other amino acids were without any significant effect. Only ornithine was a non-competitive inhibitor, where as all the other inhibitory amino acids were competitive.
D000596:Amino Acids / Q000494:pharmacology*; D000818:Animals; D001119:Arginase / Q000037:antagonists & inhibitors*; D001667:Binding, Competitive; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D010179:Pancreas / Q000201:enzymology; D012908:Snails / Q000201:enzymology*
D000596:Amino Acids; D001119:Arginase