[The suitability of further thiazine and quinoline dyes for topo-optical reactions on the plasmalemma (author's transl)].
The present studies prove that the thiazin dyes, azure B, azure C and thionin, and the quinolin dyes pinacyanol and its hydrochloride, are suitable for topo-optical staining of the plasmalemma. On the membrane surface the orientated bound dye molecules become stabilized, and with subsequent precipitation the anisotropic effect is reinforced. On optical analysis, the thiazin dye molecules (azure B, AZURE C and Thionin) are bound radially on the membrane. The molecules of the previously studied quinolin dye, N,N'-diethylpseudoisocyanide chloride are bound parallel to the membrane, while pinacyanol and its hydrochloride, like the thiazin dyes, are bound in the radial position.
D001718:Birefringence; D004396:Coloring Agents; D004910:Erythrocyte Membrane / Q000648:ultrastructure*; D004912:Erythrocytes / Q000648:ultrastructure*; D006801:Humans; D008968:Molecular Conformation; D011804:Quinolines; D013194:Staining and Labeling; D013843:Thiazines
D004396:Coloring Agents; D011804:Quinolines; D013843:Thiazines
Zur Eignung weiterer Thiazin- bzw. Chinolinfarbstoffe für die topo-optische Reaktion am Plasmalemm.