Studies on carrier protein in contact dermatitis: macrophage migration inhibition by soluble epidermal substances as carrier proteins.
The migration of peritoneal exudate cells from picrylchloride-sensitive guinea pigs can be inhibited by the water-soluble proteins present in the picrylchloride-treated guinea pig epidermis. Further examination of these proteins revealed that antigens were present in fractions with the molecular weights ranging between 10 000 and 200 000.
D000818:Animals; D002352:Carrier Proteins / Q000032:analysis; D002464:Cell Migration Inhibition; D002850:Chromatography, Gel; D003877:Dermatitis, Contact / Q000276:immunology*; D005260:Female; D006168:Guinea Pigs; D006241:Haptens / Q000032:analysis; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D008264:Macrophages / Q000276:immunology*; D008970:Molecular Weight; D010853:Picryl Chloride / Q000494:pharmacology; D012867:Skin / Q000276:immunology*
D002352:Carrier Proteins; D006241:Haptens; D010853:Picryl Chloride