[Study of the nephrotoxicity of antibodies directed against the glomerular basement membrane glycoproteins of the Wistar rat].
The nephrotoxic activity of prepared antibodies against previously isolated glycoproteic fractions of the Rat glomerular basement membrane was studied using Masugi's model of Nephritis. This activity was determined by following the daily evolution of the proteinuria and the value of the seric complement. It seems linked to numerous factors.
D000818:Animals; D000906:Antibodies; D000937:Antigen-Antibody Reactions; D001485:Basement Membrane / Q000276:immunology*; D003094:Collagen / Q000276:immunology; D003165:Complement System Proteins / Q000032:analysis; D000939:Epitopes; D005260:Female; D006023:Glycoproteins / Q000276:immunology*; D007106:Immune Sera / Q000494:pharmacology*; D007678:Kidney Glomerulus / Q000276:immunology*; D011507:Proteinuria; D011817:Rabbits; D051381:Rats
D000906:Antibodies; D000939:Epitopes; D006023:Glycoproteins; D007106:Immune Sera; D003094:Collagen; D003165:Complement System Proteins
Etude de la néphrotoxicité d'anticorps anti-glycoprotéines de membrane basale glomérulaire du rat Wistar