title: [Effect of the Y chromosome on the morphology of human F-chromatin under normal and pathological conditions].
abstract: Morphological peculiarities of brightly fluorescent chromatin (referred to as F-chromatin) in cell nuclei of buccal epithelium stained with propil-quinacrine mustard are studied in 94 healthy men and in 67 healthy women; in 4 men with 46,XYq--, I man with 46,XYq+; in 15 patients with the Kleinfelter syndrome (47,XXY) in 7 women with 46,XY and 5 males with 47,XYY. Diametre of F-chromatin bodies in buccal cells of healthy men varied within 0.9--0.2 mkm. Classification of types of interphase nuclei is proposed based on the rise, quantity and arrangement of F-chromatin bodies. The study of F-chromatin and X-chromatin showed independent behavior of these structures in cells of buccal smears obtained from 15 patients with the Kleinfelter syndrome.
mesh_terms: D000293:Adolescent; D000328:Adult; D002467:Cell Nucleus / Q000032:analysis; D002478:Cells, Cultured; D002648:Child; D002843:Chromatin / Q000032:analysis*; D005260:Female; D005453:Fluorescence; D006570:Heterochromatin / Q000032:analysis; D006801:Humans; D007621:Karyotyping; D007962:Leukocytes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011797:Quinacrine Mustard; D012728:Sex Chromatin / Q000032:analysis; D012729:Sex Chromosome Aberrations / Q000235:genetics / Q000473:pathology*; D012730:Sex Chromosomes; D013194:Staining and Labeling / Q000379:methods; D014998:Y Chromosome
chemical_list: D002843:Chromatin; D006570:Heterochromatin; D011797:Quinacrine Mustard
vernacular_title: Vliianie Y-khromosomy v norme i patologii na morfologiiu F-khromatina cheloveka.