Rapid detection of ringed sideroblasts with bromchlorphenol blue.
A test for demonstrating ringed sideroblasts was developed, using the dye bromchlorphenol blue. The test is based upon the ability of the dye to form a colored water-insoluble precipitate with iron. Because it is rapid and permits localization of ferritin-containing cytoplasmic inclusions, the reaction may be useful in the assessment of sideroblastic anemias.
D000756:Anemia, Sideroblastic / Q000175:diagnosis*; D001853:Bone Marrow / Q000032:analysis; D001854:Bone Marrow Cells; D001978:Bromphenol Blue; D011232:Chemical Precipitation; D005069:Evaluation Studies as Topic; D006651:Histocytochemistry; D006801:Humans; D007501:Iron / Q000032:analysis*; D010636:Phenols; D013194:Staining and Labeling; D013997:Time Factors
D010636:Phenols; D001978:Bromphenol Blue; D007501:Iron