title: [Vascularization of the ganglion spirale cochleae of the rat (author's transl)].
abstract: Investigation into the vascularization of the Ganglion spirale of the rat showed an irregular, loose network of capillaries, with a somewhat denser vacularization of the marginal areas of the ganglion; the horseradish peroxidase benzidine test according to Sugar was used to demonstrate the vessels. At least of the blood supply of the ganglion is effected via the vessels which run parallel to the nerve fibres through the osseous canals from the modiolus into the Rosenthal canal. The density of vascularization of the Ganglion spirale is surprisingly small, namely 1.89% by volume. The comparative figure for the Ganglion spirale, also measured by means of stereological methods, is approximately 6.8% by volume, whilst the vessels in the Nervus cochlearis occupy 2.1% by volume. The vascularization density of the ganglion corresponds roughly to that of the Cortex cerebri. Electro-microscopical tests have shown that there are unfenestrated capillaries with a small number of pinocytotic vesicles. Possible conclusions as to the permeability of the capillaries are discussed in the paper. The blood supply of the Ganglion spirale has so far received only little attention. In the case of internal ear diseases of vascular genesis, attention is mainly given to changes in the vessels of the lateral wall of the cochlea. Experimental findings, however, show the high sensitivity of the nervous apparatus of the cochlea in the case of disturbed blood supply.
mesh_terms: D003056:Cochlear Nerve / Q000098:blood supply* / Q000166:cytology / Q000648:ultrastructure; D003720:Densitometry; D006735:Horseradish Peroxidase; D006801:Humans; D007759:Labyrinth Diseases / Q000473:pathology; D008853:Microscopy; D008854:Microscopy, Electron; D013194:Staining and Labeling; D014652:Vascular Diseases / Q000473:pathology
chemical_list: D006735:Horseradish Peroxidase
vernacular_title: Vaskularisation des Ganglion spirale cochleae der Ratte.