title: Detection of bursa and thymus-specific alloantigens in the chicken.
abstract: CH strain chickens selected from the F2 progeny of a cross between CH (B10/10) and B14B (B14/14) strains carried bursa (BA) and thymus (TA)-specific alloantigens of B14B parental origin. The BA marker was present on 95% of bursal cells but only on 10% of splenic and blood B lymphocytes. The TA marker was expressed by 80% of thymus cells and weakly by 45% of splenic and 70% of blood T lymphocytes. The adopted immunological and genetic protocol offers a feasible approach towards detection of differentiation antigens in major histocompatibility complex-homozygous but 'minor' alloantigen-segregating populations.
mesh_terms: D000818:Animals; D000961:Antilymphocyte Serum / Q000494:pharmacology; D002060:Bursa of Fabricius / Q000276:immunology*; D002645:Chickens; D000939:Epitopes; D005455:Fluorescent Antibody Technique; D007163:Immunosorbent Techniques; D007519:Isoantigens / Q000032:analysis*; D008214:Lymphocytes / Q000276:immunology; D013154:Spleen; D013601:T-Lymphocytes / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology*
chemical_list: D000961:Antilymphocyte Serum; D000939:Epitopes; D007519:Isoantigens