title: [Evidence for polypeptide synthesis during cytotoxic reactions in sipunculid worms].
abstract: The occurence of a polypeptidic synthesis during the in vitro cytotoxic reaction of sipunculid worns is demonstrated. Some drugs such as actinomycin D, cycloheximide, cytochalasin B, Colchicine, vinblastine and iodoacetate have been tested. Hypothesis are expressed on the use of the products synthetized by leukocytes.
mesh_terms: D000818:Animals; D003078:Colchicine / Q000494:pharmacology; D003513:Cycloheximide / Q000494:pharmacology; D003571:Cytochalasin B / Q000494:pharmacology; D003609:Dactinomycin / Q000494:pharmacology; D007448:Invertebrates / Q000378:metabolism*; D007461:Iodoacetates / Q000494:pharmacology; D010452:Peptide Biosynthesis; D014176:Protein Biosynthesis / Q000187:drug effects*; D014747:Vinblastine / Q000494:pharmacology
chemical_list: D007461:Iodoacetates; D003609:Dactinomycin; D003571:Cytochalasin B; D014747:Vinblastine; D003513:Cycloheximide; D003078:Colchicine
vernacular_title: Mise en évidence d'une synthèse polypeptidique au cours de la réaction de cytotoxicité chez les Siponcles.