[The "IgA secretory component complex" in bronchial mucus in patients with chronic obstructive lung disease under different therapy (author's transl)].
The concentration of "IgA secretory component complex" in the bronchial mucus was measured under different therapeutical influences. The "IgA secretory component complex" is a most important factor of the exogenous immunodefense. The formation of the "IgA secretory component complex" was independent from the age of the patients and from the intensity of their airway obstruction. Therapy with glucocorticosteroids and antibiotics had no certain influence on the formation of the immunocomplex. We did not find any certain influence of gammaglobulin therapy in adult patients with chronic airway obstruction, neither on the "IgA secretory component complex" nor on the immunoglobulin G, A and M. Furthermore, the clinical course of the disease was not influence by this therapy.
D000328:Adult; D000367:Age Factors; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001980:Bronchi / Q000378:metabolism; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D007071:Immunoglobulin A, Secretory / Q000276:immunology*; D008173:Lung Diseases, Obstructive / Q000188:drug therapy / Q000276:immunology*; D009093:Mucus / Q000276:immunology* / Q000378:metabolism; D005719:gamma-Globulins / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D005938:Glucocorticoids; D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D005719:gamma-Globulins
Der "IgA-Secretory-Component-Complex" im Bronchialschleim bei chronischer Atemwegsobstruktion unter verschiedenen Therapieformen.