Preventing malignant-cell transfer during endoscopic brush cytology.
Transfer of malignant cells on cytology brushes was responsible for false positive cytology reports in 4 patients. In 24 examinations of cytology brushes after patients with gastric carcinoma had been previously endoscoped, malignant cells were identified on 7 occasions. Satisfactory irradication of malignant cells was achieved by autoclaving the brushes for 15 min, not by cleaning with chlorhexidine or pancreatin. Although these observations may argue against the use of non-disposable brushes, non-disposable brushes provide a higher yield of cells and are cheaper than disposable brushes.
D002452:Cell Count / Q000295:instrumentation; D003581:Cytodiagnosis / Q000295:instrumentation*; D005189:False Positive Reactions; D020699:Gastroscopes; D006801:Humans; D013048:Specimen Handling / Q000379:methods*; D013242:Sterilization; D013274:Stomach Neoplasms / Q000473:pathology*