[Metabolism and organ functions in experimental hypothermic, bloodless whole-body perfusion with hydroxyethyl starch (HES)].
After surface-induced hypothermia in 12 cats total body washout was performed followed by 60 min bloodless perfusion. In the rewarming period at 28 degrees C, packed red cells were added and at 35 degrees C, ECC was finished. Functional parameters of metabolism, liver, and kidney were measured and followed by histologic examination. Bloodless perfusion does not alter the morphology of the organs examined. Abnormal values of organ function and metabolic data seem to be reversible.
D000818:Animals; D001810:Blood Volume; D002415:Cats; D006439:Hemodynamics / Q000187:drug effects; D006895:Hydroxyethyl Starch Derivatives / Q000494:pharmacology*; D007035:Hypothermia / Q000097:blood* / Q000503:physiopathology; D010477:Perfusion / Q000379:methods*; D010974:Platelet Aggregation / Q000187:drug effects; D013213:Starch / Q000031:analogs & derivatives*
D006895:Hydroxyethyl Starch Derivatives; D013213:Starch
Stoffwechsel und Organfunktionen bei hypothermer, blutfreier Ganzkörperfusion mit Hydroxyäthylstärke (HAS) im Tierexperiment.