Comparison of sucrose with glucose in oral therapy of infant diarrhoea.
In a randomised double-blind trial, 51 5--10% dehydrated infants were rehydrated with oral electrolyte solutions containing sucrose or glucose. Most infants in both groups were successfully rehydrated, but the sucrose solution produced a slower correction of electrolyte abnormalities and a higher percentage of patients who needed more than 24 h of therapy. Where there is adequate knowledge of the oral therapy method sucrose can substitute for glucose in many cases; where there is a choice glucose is recommended.
D000208:Acute Disease; D000284:Administration, Oral; D002986:Clinical Trials as Topic; D003364:Costa Rica; D003681:Dehydration / Q000188:drug therapy; D003968:Diarrhea, Infantile / Q000188:drug therapy*; D004341:Drug Evaluation; D004756:Enterobacteriaceae Infections / Q000188:drug therapy; D005260:Female; D005873:Giardiasis / Q000188:drug therapy; D005947:Glucose / Q000008:administration & dosage*; D005950:Glucose Solution, Hypertonic / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D008297:Male; D012107:Research Design; D012401:Rotavirus; D012996:Solutions; D013395:Sucrose / Q000008:administration & dosage*; D014777:Virus Diseases / Q000188:drug therapy
D005950:Glucose Solution, Hypertonic; D012996:Solutions; D013395:Sucrose; D005947:Glucose