RNA-dependent DNA polymerase activity in intracytoplasmic type-a particles of mouse mammary tumors.
Intracytoplasmic type-A particles isolated from mouse mammary tumors and purified by repeated gradient centrifugations exhibit both endogenous and exogenous (template-stimulated) RNA-dependent DNA polymerase activities. The enzyme has a preference for magnesium ions.
D000818:Animals; D006824:Hybridization, Genetic; D008325:Mammary Neoplasms, Experimental / Q000201:enzymology*; D051379:Mice; D012334:RNA, Neoplasm / Q000378:metabolism*; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism*
D012334:RNA, Neoplasm; D012194:RNA-Directed DNA Polymerase