title: [Sensitization to mites in house dust among children suffering bronchial asthma].
abstract: The results of studying allergy to domestic dust in 168 patients suffering from bronchial asthma are presented. The diagnosis was made by means of the domestic dust allergen (10000 PNU), fraction E extracted from the whole allergen by Berrens and Young's method, and with lyophilized extract from D. pteronussinus, farinae and Glycyphagus ticks isolated from domestic dust by Voohorst and Spieksma's method. In parallel, IgE was determined in the blood serum of the patients under study by the radio-allergo-sorbent test; IgG was also determined. Microticks proved to be not the only factor determining the activity of domestic dust. Results of diagnosis in vivo and in vitro were found to correlate. The authors believe that the activity of domestic dust allergen formed on account of the reactions of the Maillard's type, in which a significant role was played by the "lysine-sugar) compounds.
mesh_terms: D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000032:analysis*; D001249:Asthma / Q000276:immunology*; D002648:Child; D004391:Dust / Q000032:analysis*; D000939:Epitopes; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D008875:Middle Aged; D008925:Mites / Q000276:immunology*; D012882:Skin Tests
chemical_list: D000485:Allergens; D004391:Dust; D000939:Epitopes; D007074:Immunoglobulin G; D007073:Immunoglobulin E
vernacular_title: Izuchenie sensibilizatsii k mikrokleshcham v domashneĭ pyli u liudeĭ, stradaiushchikh bronkhial'noĭ astmoĭ.