[Combined doxorubicin and bleomycin treatment of metastasising thyroid carcinoma: results in 21 patients (author's transl)].
The effectiveness of combined cytostatic treatment with doxorubicin and bleomycin was analysed in 21 patients with metastasising thyroid carcinoma which had progressed despite both surgical and radiotherapy. Tumour histology (anaplastic carcinoma in 50%), age and general condition of all patients pointed to a poor prognosis. Significant success (full or partial remission) occurred in eight patients. It is possible that these results can be improved if chemotherapy is started earlier and other cytostatic drugs are used in case of failure of treatment.
D000328:Adult; D000367:Age Factors; D000368:Aged; D001761:Bleomycin / Q000627:therapeutic use*; D004317:Doxorubicin / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011379:Prognosis; D012075:Remission, Spontaneous; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology
D001761:Bleomycin; D004317:Doxorubicin
Zytostatische Kombinationsbehandlung metastasierender Schilddrüsenkarzinome mit Doxorubicin und Bleomycin. Ergebnisse bei 21 Patienten.