title: Degradation of lindane by cell-free preparations of Clostridium sphenoides.
abstract: Cell-free preparation of Clostridium sphenoides degraded the insecticide lindane, the gamma-isomer of 1,2,3,4,5,6-hexachlorocyclohexane, to the gamma-isomer of 3,4,5,6-tetrachloro-1-cyclohexene. The activity appeared to be associated with the membrane fraction and required reduced glutathione. The tetrachlorocy-clohexene intermediate was further metabolized by the membrane fraction to unknown substances.
mesh_terms: D001673:Biodegradation, Environmental; D002462:Cell Membrane / Q000378:metabolism; D002474:Cell-Free System; D003013:Clostridium / Q000378:metabolism*; D003510:Cyclohexanes / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D001556:Hexachlorocyclohexane / Q000378:metabolism*; D013347:Subcellular Fractions
chemical_list: D003510:Cyclohexanes; D001556:Hexachlorocyclohexane; D005978:Glutathione