Cellular content of amniotic fluid as predictor of central nervous system malformations.
Prospective observations on 442 consecutive samples have confirmed that pregnancies with CNS malformations are regularly associated with an abnormal cellular content of amniotic fluid. A crude semiquantitative test of the cell content can give valuable clinical information in relation to borderline amniotic fluid alpha-fetoprotein values, and help to detect false positive AFP's.
D000649:Amniocentesis; D000653:Amniotic Fluid / Q000166:cytology* / Q000378:metabolism; D002490:Central Nervous System / Q000002:abnormalities*; D005260:Female; D006801:Humans; D008264:Macrophages / Q000473:pathology; D011247:Pregnancy; D000509:alpha-Fetoproteins / Q000378:metabolism
D000509:alpha-Fetoproteins