title: [Current status in the treatment of breast cancer. II. Adjuvant chemotherapy, palliative polychemotherapy, chemoimmunotherapy--rating and results (author's transl)].
abstract: There is no well defined group of patients with primary breast cancer which benefits from combination chemotherapy as an adjuvant treatment, since, at present, the effect of this therapy in respect to the duration of disease-free interval, survival, and possible long-term side effects remain unknown. Therefore, controlled studies need to be initiated. Similarly, there seems to be no beneficial effect from unspecific immunotherapy. As far as combination chemotherapy in advanced breast cancer is concerned, we review on four different protocols which proved to be quite successful in our hands: adriamycine/cyclophosphamide (AC), cyclophosphamide/methotrexate/5-fluorouracil (CMF), CMF/vincristine/prednisone (CMFVP), and adriamycine/vincristine plus CMF plus Tamoxifen.
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D001943:Breast Neoplasms / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004965:Estrogen Antagonists / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D008593:Menopause / Q000187:drug effects; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D010166:Palliative Care / Q000379:methods*; D012075:Remission, Spontaneous; D012306:Risk; D014626:Vaginal Smears
chemical_list: D000970:Antineoplastic Agents; D004965:Estrogen Antagonists
vernacular_title: Zum gegenwärtigen Stand der internistischen Therapie des Mammacarcinoms. II. Adjuvante Chemotherapie, palliative Polychemotherapie, Chemoimmuntherapie--Stellenwert und Ergebnisse.