Induction of allergic encephalomyelitis using hydrosoluble mycobacterial fractions.
Experimental allergic encephalomyelitis has been induced in guinea pigs employing bovine myelin basic protein as the antigen and a hydrosoluble tetrasaccharide-heptapeptide from delipidated cells of the human mycobacterial strain H37Ra as adjuvant. The maximum response was observed using 33 mug of antigen and 12.5 mug of adjuvant per animal.
D000276:Adjuvants, Immunologic; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000209:etiology*; D006020:Glycopeptides / Q000276:immunology; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D004676:Myelin Basic Protein / Q000276:immunology; D012995:Solubility
D000276:Adjuvants, Immunologic; D006020:Glycopeptides; D004676:Myelin Basic Protein