title: Antibody-like activity to polyacrylic acid in normal rabbit sera.
abstract: Most unimmunized rabbit sera agglutinate acrylic particles coated with polyacrylic acid. The factor responsible for the agglutinating activity turned out to be a 2-mercaptoethanol-resistent immunoglobulin, present in low concentration. It was tentatively classified as "natural antibody". This is assumed to have arisen upon previous contact with naturally occurring cross-reacting polyanions.
mesh_terms: D000179:Acrylates / Q000276:immunology*; D000371:Agglutination / Q000187:drug effects; D000818:Animals; D000906:Antibodies; D011817:Rabbits / Q000276:immunology; D013386:Succinates / Q000494:pharmacology; D005719:gamma-Globulins
chemical_list: D000179:Acrylates; D000906:Antibodies; D013386:Succinates; D005719:gamma-Globulins