Jejunal morphology in multiple sclerosis.
In a prospective survey jejunal biopsy samples from 11 patients with multiple sclerosis on normal diets were compared with those from controls matched for age and sex. Quantitative histology, morphometry, and electron microscopy showed no difference between the two groups. Since there was no evidence that gluten sensitivity plays a role in the aetiology of multiple sclerosis, the wide adoption of gluten exclusion by patients seems unjustified.
D000328:Adult; D000368:Aged; D002452:Cell Count; D005260:Female; D005983:Glutens / Q000633:toxicity; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology / Q000648:ultrastructure; D007583:Jejunum / Q000473:pathology* / Q000648:ultrastructure; D007958:Leukocyte Count; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000209:etiology / Q000473:pathology*; D010950:Plasma Cells / Q000473:pathology
D005983:Glutens