Death from acute pancreatitis. M.R.C. multicentre trial of glucagon and aprotinin.
The influence of glucagon and aprotinin ('Trasylol') on the death-rate of acute pancreatitis has been studied in a randomised double-blind multicentre trial. The death-rate in 257 patients was 11%. In the doses used neither drug was found to diminish the risk of death.
D000208:Acute Disease; D000328:Adult; D000367:Age Factors; D000368:Aged; D007611:Aprotinin / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004334:Drug Administration Schedule; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D005934:Glucagon / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000188:drug therapy / Q000209:etiology / Q000401:mortality*; D010919:Placebos; D012744:Sex Ratio
D010919:Placebos; D005934:Glucagon; D007611:Aprotinin