Specific cell-induced transformation of Paramecium surface antigens.
Paramecia may induce in other paramecia specific changes in the expression of genes determining surface protein synthesis, probably via cell-to-cell contact. Transformation from one antigenic type to a newly induced one is stimulated by the pretreatment of a cell with 5-fluorouracil. These observations are considered in terms of the regulation of the activity of genes in stable cells and in unstable cells which tend to transform spontaneously.
D000818:Animals; D000941:Antigens; D002450:Cell Communication; D002462:Cell Membrane / Q000276:immunology; D000939:Epitopes; D007125:Immunogenetics; D008565:Membrane Proteins / Q000276:immunology*; D010247:Paramecium / Q000276:immunology; D010641:Phenotype
D000941:Antigens; D000939:Epitopes; D008565:Membrane Proteins