A haemorrhagic bullous eruption of the hands caused by phenylbutazone: a report of 3 cases.
Three patients developed a haemorrhagic eruption on the hands after taking phenylbutazone. The reaction appeared within two weeks of taking the drug and is probably an allergic capillaritis. All patients showed generalised capillary fragility with a positive Hess test which became negative within a week of stopping the drug. A mechanism is suggested for the development and distribution of the blisters.
D000328:Adult; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006229:Hand Dermatoses / Q000139:chemically induced; D006470:Hemorrhage / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged; D010653:Phenylbutazone / Q000009:adverse effects; D012867:Skin / Q000098:blood supply
D010653:Phenylbutazone