[Oncornavirus activation and accumulation in cell cultures under the influence of hormones].
Sex hormones (testosterone, estradiol) and thyroxine would activate irregularly the production of the specific group antigen (GS-antigen) of avian ribodesoxyviruses in the culture of "normal" chick embryonal cells (CEC, phenotype C/O, GS-). The mentioned hormones as well as hydrocortisone and insulin would not prevent the Rous sarcoma virus (RSV) infecting of CEC, render no essential action on the accumulation of RSV in the infected CEC culture, and failed to activate the formation of mature RSV in virogenic cultures of rat (XC, R--B77) and mice cells (DBA--B77).
D000818:Animals; D000956:Antigens, Viral; D001358:Avian Sarcoma Viruses / Q000187:drug effects; D002478:Cells, Cultured; D002642:Chick Embryo; D000939:Epitopes; D004958:Estradiol / Q000494:pharmacology; D005814:Genes, Viral / Q000187:drug effects; D006728:Hormones / Q000494:pharmacology*; D006854:Hydrocortisone / Q000494:pharmacology; D051379:Mice; D051381:Rats; D012190:Retroviridae / Q000187:drug effects*; D013739:Testosterone / Q000494:pharmacology; D013974:Thyroxine / Q000494:pharmacology; D014776:Virus Cultivation; D014779:Virus Replication / Q000187:drug effects
D000956:Antigens, Viral; D000939:Epitopes; D006728:Hormones; D013739:Testosterone; D004958:Estradiol; D013974:Thyroxine; D006854:Hydrocortisone
Izuchenie aktivatsii i nakopleniia onkornavirusa v kul'turakh kletok pod vliianiem nekotoryk gormonov.