[Pulse cytophotometric and cytologic repeated examinations of cervical secretions as compared with histologic findings (author's transl)].
1625 cervical smears from 397 women were investigated in special cytological consultations. On the same material 693 impulse cytophotometric (ICP) measurements were made, stained with ethidium bromide after pepsination. In 207 patients the diagnosis was certain by histology. The mean height of the 4c-peak (in 0/00 of the 2c-peak) raises with the Papanicolaou grading from 38,2 in Pap. I up to 128,8 in Pap. V. In histological confirmed cases in dysplasia the mean 4c-height was 79,5 and in carcinoma 102.2. If only one ICP investigation was turned to account there are some disagreements between the ICP value and the diagnosis finally resulting from the clinical and cytological course. The differences are considerably diminished by repeated ICP investigations. Therefore ICP measurements are a valuable aid in interpreting cytodiagnostic problems. They often facilitate the choice of further diagnostic and therapeutic procedures.
D002584:Cervix Uteri / Q000473:pathology*; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D008722:Methods; D065006:Papanicolaou Test; D013194:Staining and Labeling; D002583:Uterine Cervical Neoplasms / Q000473:pathology; D014626:Vaginal Smears
Impulszytophotometrische und zytologische Mehrfachuntersuchungen am Zervixsekret mit histologischen Vergleichen