[Incorporation of tritiated amino acids into the ultrastructure of the cerebral cortex following phenamine stimulation].
The method of electronoscopic autoradiography has revealed an increased biosynthesis of protein by neuronal and glial cells of the motor cortex of rats under phenamine stimulation. The increased level of incorporation of labelled precursors in the molecular layer of the cortex is likely to be associated with increased accumulation of newly synthetized protein in axo-dendritic synapses due to stimulation of the rapid component of the axonal transport of macromolecules. At the same time, participation of the autonomic protein-synthetizing system in the biosynthesis of synaptic proteins is not excluded. The labelled products were found to localize in the field of the thorn apparatus in processes of the "structural-functional" adaptation of synaptic entrances (A. A. Manina, 1972).
D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D001345:Autoradiography; D001370:Axonal Transport; D001369:Axons / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism; D003712:Dendrites / Q000378:metabolism; D008297:Male; D008854:Microscopy, Electron; D008928:Mitochondria / Q000378:metabolism; D009044:Motor Cortex / Q000166:cytology / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D009457:Neuroglia / Q000378:metabolism; D009474:Neurons / Q000378:metabolism; D051381:Rats; D012270:Ribosomes / Q000378:metabolism; D013569:Synapses / Q000378:metabolism
D009419:Nerve Tissue Proteins; D000661:Amphetamine
Vkliuchenie tritirovannykh aminokislot v ul'trastruktury kory golovnogo mozga pri fenaminovoĭ stimuliatsii