Antigen recognition by T lymphocytes (status of the minimal hypothesis).
Data of recent studies based upon three approaches to the problem of the T cell receptor for antigen, namely, use of "anti-receptor" (= anti-idiotype) antibodies, utilization of antisera made against circulating antibodies in association with physiochemical characterization procedures, and phylogenetic investigations, support the conclusion that this recognition molecule is an immunoglobulin, but that it represents as isotype distinct from usual circulating antibodies and B cell surface IgM- and IgD-like molecules.
D000906:Antibodies / Q000032:analysis; D001666:Binding Sites, Antibody; D002462:Cell Membrane / Q000276:immunology; D000939:Epitopes; D006680:HLA Antigens; D006801:Humans; D007106:Immune Sera; D007136:Immunoglobulins / Q000032:analysis; D013601:T-Lymphocytes / Q000276:immunology*
D000906:Antibodies; D000939:Epitopes; D006680:HLA Antigens; D007106:Immune Sera; D007136:Immunoglobulins