Effectiveness of parenteral and oral typhoid vaccination in mice challenged with a Salmonella typhi-Salmonella typhimurium hybrid.
Live Salmonella typhi administered intraperitoneally, acetone-killed S. typhi administered intraperitoneally, and live S. typhi given orally, with their effectiveness decreasing in that order, protected Swiss white mice against death from challenge with a virulent Salmonella typhimurium hybrid expressing S. typhi antigens.
D000284:Administration, Oral; D000818:Animals; D000942:Antigens, Bacterial; D001428:Bacterial Vaccines / Q000008:administration & dosage; D000939:Epitopes; D006824:Hybridization, Genetic; D007274:Injections, Intraperitoneal; D051379:Mice; D012485:Salmonella typhi / Q000276:immunology*; D012486:Salmonella typhimurium / Q000276:immunology*
D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D000939:Epitopes