Local excision in the treatment of oral discoid lupus erythematosus.
Oral lesions in eight patients with discoid lupus erythematosus (DLE)  were treated with local excision. Ten well-demarcated oral lesions were excised and a primary closure was obtained following the excision. Six patients out of seven became symptom-free following the treatment. The median observation time was 1.0 year. The follow-up examination showed erythema in one case and recurrence in one case at the operation site. In the remaining eight operation sites, a soft scar with no sign of recurrence was seen. These results indicate that the method should be investigated further in order to obtain long-term results. Local excision of oral discoid lesions may be a valuable therapeutic supplement in some cases of DLE.
D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000601:surgery*; D009061:Mouth Mucosa / Q000473:pathology / Q000601:surgery*