HLA-DRW4 in 91% of Jewish pemphigus vulgaris patients.
HLA-DRW4 was found in all 11 female and 10 out of 12 male Jewish patients with pemphigus vulgaris, a frequency of 91% in all, which was significantly higher than the 25% frequency among normal Jewish controls. The relative risk was 31.5. The BW38-DRW4 haplotype occurred in 12 out of 22 patients (55%) but in only 2% of White non-Jews and 11% of normal Jewish people.
D002140:California; D000939:Epitopes; D005260:Female; D005787:Gene Frequency; D005802:Genes, MHC Class II; D006680:HLA Antigens / Q000235:genetics*; D006238:Haploidy; D006801:Humans; D007585:Jews; D008297:Male; D010392:Pemphigus / Q000235:genetics* / Q000276:immunology; D012737:Sex Factors
D000939:Epitopes; D006680:HLA Antigens