title: Serological identification of the new cold agglutinin specificity anti-Gd.
abstract: The specificity anti-Gd of human cold autoagglutinins is characterized using untreated and enzyme-treated human red blood cells. Gd determinants of human RBC are resistant to proteases, but are inactivated by neuraminidase (RDE). In contrast, I/i determinants are not inactivated by proteases or RDE, while Pr1-3 determinants are inactivated by proteases and RDE, and Pra determinants are resistant to RDE, but are inactivated by proteases.
mesh_terms: D000373:Agglutinins; D000918:Antibody Specificity; D001323:Autoantibodies; D001789:Blood Group Antigens; D003080:Cold Temperature; D000939:Epitopes; D006801:Humans; D009439:Neuraminidase / Q000378:metabolism; D010447:Peptide Hydrolases / Q000378:metabolism; D012794:Sialic Acids / Q000378:metabolism
chemical_list: D000373:Agglutinins; D001323:Autoantibodies; D001789:Blood Group Antigens; D000939:Epitopes; D012794:Sialic Acids; D009439:Neuraminidase; D010447:Peptide Hydrolases