Effects of biotin deficiency on serum proteins and plasma amino acids.
In biotin-deficient rats, a decrease of total proteins, attributable to a decrease of albumin and alpha1-globulin fractions, a decrease of the pre-beta-lipoproteins and an increase of the alpha-lipoproteins, was observed, together with a rise of total amino acids. Such a situation  may be related to the influence of biotin on the synthesis of RNA and proteins.
D000510:Alpha-Globulins / Q000378:metabolism; D000596:Amino Acids / Q000097:blood*; D000818:Animals; D001710:Biotin / Q000172:deficiency*; D001798:Blood Proteins / Q000378:metabolism*; D005260:Female; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D051381:Rats; D012709:Serum Albumin / Q000378:metabolism
D000510:Alpha-Globulins; D000596:Amino Acids; D001798:Blood Proteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D012709:Serum Albumin; D001710:Biotin