Liver biopsy in PUVA-treated patients.
Seventy-five liver biopsies were performed in 30 psoriatics and 5 patients with mycosis fungoides undergoing treatment with photochemotherapy with 8-methoxypsoralen and UVA light. All patients had pre- and post-PUVA biopsies, the latter after one year. Five psoriatics had a further biopsy after 2 1/2 years of treatment. No statistically significant differences were found between biopsies taken before and after treatment.
D000328:Adult; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008297:Male; D008730:Methoxsalen / Q000009:adverse effects* / Q000627:therapeutic use; D009182:Mycosis Fungoides / Q000188:drug therapy; D010778:Photochemotherapy / Q000009:adverse effects*; D011565:Psoriasis / Q000188:drug therapy; D012878:Skin Neoplasms / Q000188:drug therapy; D014467:Ultraviolet Therapy
D008730:Methoxsalen