Is granulopoietic activity (GA) in vivo comparable to colony stimulating factor (CSF)?
Human sera after column chromatography on Sephadex G-200 were tested for Granulopoietic Activity (GA) in vivo and Colony Stimulating Factor (CSF) in vitro. We have found that GA after chromatography is distributed in three peaks but CSF only in one peak with high activity, and evident activity in volume 135 ml. This activities are in good agreement with two peaks of GA. We assume that GA and CSF after this chromatographic procedure is free from lipoproteins inhibitors. The obtained results are briefly discussed.
D000818:Animals; D003115:Colony-Stimulating Factors; D006098:Granulocytes; D006410:Hematopoiesis; D008297:Male; D051379:Mice
D003115:Colony-Stimulating Factors