title: Use of methylene blue in suspected colovesical fistula.
abstract: Positive urine and blood assays of methylene and leukomethylene blue were obtained from 9 volunteers with normal colonic and renal function after a 100 ml, methylene blue enema (50 mg.). The study conclusively demonstrates that methylene blue is absorbed by rectal mucosa and excreted by the kidneys as a colored dye in the urine. Thus, intrarectal methylene blue cannot be used to confirm the diagnosis of a colovesical fistula.
mesh_terms: D003108:Colonic Diseases / Q000175:diagnosis*; D004733:Enema; D006801:Humans; D007412:Intestinal Fistula / Q000175:diagnosis*; D007413:Intestinal Mucosa / Q000378:metabolism; D008297:Male; D008751:Methylene Blue / Q000031:analogs & derivatives / Q000378:metabolism / Q000652:urine; D013194:Staining and Labeling; D001747:Urinary Bladder Fistula / Q000175:diagnosis*
chemical_list: C011010:hydromethylthionine; D008751:Methylene Blue