title: [Kidney complications in chronic polyarthritis].
abstract: 50 patients with definite rheumatoid arthritis treated with D-penicillamine were studied every 4 weeks by disk electrophoresis of the urine to make an early record of the glomerular proteinuria of the immune complex nephritis, which has been described as a side effect of this treatment. In 30 of these patients we found, however, a tubular proteinuria which correlated well with the disease activity and which disappeared after successful basic treatment. This finding indicates interstitual renal involvement due to the basic disease.
mesh_terms: D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000175:diagnosis; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D005921:Glomerulonephritis / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D010396:Penicillamine / Q000627:therapeutic use; D011507:Proteinuria / Q000175:diagnosis; D014168:Transferrin / Q000652:urine; D005719:gamma-Globulins / Q000652:urine
chemical_list: D014168:Transferrin; D005719:gamma-Globulins; D003520:Cyclophosphamide; D010396:Penicillamine
vernacular_title: Nierenbeteiligung bei chronischer Polyarthritis.