[Immunochemical investigations on the protein of the "pregnancy zone". XI. Serum concentration of the pregnancy-associated alpha2-glycoprotein (Pregnancy Zone protein) in normal pregnancy (author's transl)].
A quantitative study of the pregnancy zone proteins was made in the sera of 383 healthy pregnant women by means of radial immunodiffusion according to Mancini and co-workers. The serum levels related to a pregnancy serum standard were measured from the 6th to 44th week of pregnancy. The serum concentration of the protein showed a considerable individual variation. The mean concentration began to rise in gestational weeks 8 to 24. Until the week 32 a rather stable average level was reached. Before delivery a slight decrease was observed. Women with over term pregnancies showed particular high mean concentrations. The differences of serum levels were statistically significant until the gestational week 14.
D000818:Animals; D005260:Female; D006801:Humans; D005779:Immunodiffusion; D011247:Pregnancy; D011817:Rabbits / Q000276:immunology; D013997:Time Factors; D000511:alpha-Macroglobulins / Q000032:analysis*
D000511:alpha-Macroglobulins
Immunchemische Untersuchungen zum Problem der "pregnancy zone". XI. Die Serumkonzentration des schwangerschaftsassoziierten alpha2-Glykoproteins (Protein der "pregnancy zone") in der normalen Schwangerschaft