Regulation of rat alpha-fetoprotein production by methionine and adenosine 5'-triphosphate.
Simultaneous and equimolar injections of methionine and adenosine 5'-triphosphate significantly accelerated the rapid fall of rat serum alpha-fetoprotein (AFP) concentrations after birth. The results were compared with those obtained by administrations of prednisolone and adult tissue extracts. Correlations between a methionine-related metabolic event(s) and the repression of AFP synthesis were discussed.
D000255:Adenosine Triphosphate / Q000494:pharmacology*; D000818:Animals; D003864:Depression, Chemical; D005260:Female; D008297:Male; D008715:Methionine / Q000494:pharmacology*; D011239:Prednisolone / Q000494:pharmacology; D051381:Rats; D000509:alpha-Fetoproteins / Q000096:biosynthesis* / Q000097:blood
D000509:alpha-Fetoproteins; D000255:Adenosine Triphosphate; D011239:Prednisolone; D008715:Methionine