Non-renin-mediated renovascular hypertension: A new syndrome?
In two hypertensive patients with renal-artery stenosis, overactivity of the renin-angiotensin system was ruled out by investigations of renin and aldosterone concentrations and by the lack of a vasodepressor response to angiotensin blockade with saralasin. Nevertheless, hypertension was cured by renal revascularisation. The date suggest that there is a form of renovascular hypertension which is not mediated by the renin-angiotensin system.
D000328:Adult; D000450:Aldosterone / Q000097:blood; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D016030:Kidney Transplantation; D008875:Middle Aged; D011187:Posture; D012078:Renal Artery Obstruction / Q000150:complications* / Q000601:surgery; D012083:Renin / Q000097:blood; D012504:Saralasin; D013577:Syndrome; D014182:Transplantation, Autologous
D000450:Aldosterone; D012083:Renin; D012504:Saralasin