[Close genetic relation between determinants coding for the HLA-D region, detected by the technique of mixed primary and secondary lymphocyte culture and by serology of B lymphocytes].
In this study we report that: 1. Li determinants serologically detectable or closely linked structures are more associated to secondary responses than HLA-D specificities defined by HTC testing; 2. Other determinants from loci, MHC linked, or cross reactivity between Li determinants must be postulated to explain discrepancies between secondary responses and B serology; 3. Li determinants have an effect on the intensity of the reaction in primary allogenic proliferation.
D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology*; D001789:Blood Group Antigens; D002478:Cells, Cultured; D002648:Child; D000939:Epitopes; D005260:Female; D005815:Genetic Code; D006680:HLA Antigens; D006720:Homozygote; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008722:Methods; D010375:Pedigree
D001789:Blood Group Antigens; D000939:Epitopes; D006680:HLA Antigens
Relations génétiques étrottes entre des déterminants codés par la région HLA-D, décelés par la technique de culture lymphocytaire mixte primaire et secondaire et par la sérologie des lymphocytes B.