Sudanophilia in exfoliated urothelial cells.
Cytoplasmic lipid globules colorable by Oil Red O of varying numbers, size and random distribution were encountered in the majority of normal, abnormal and malignant urothelial cells of the urinary sediments fixed by formaldehyde. Small cytoplasmic lipid globules and the diffuse sudanophilia of the finely dispersed lipids which paralleled the cyanophilia in the homologous cells were considered indicators of the functional status of well preserved urothelial cells; medium and large lipid globules were a sign of advanced necrobiosis. Demonstration of cytoplasmic lipids was not found a reliable discriminatory guide in the differential diagnosis of malignancy of the urothelium.
D003556:Cystitis / Q000473:pathology / Q000652:urine; D006801:Humans; D008055:Lipids / Q000032:analysis*; D009504:Neutrophils / Q000032:analysis; D013194:Staining and Labeling; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000652:urine; D014556:Urine / Q000166:cytology*
D008055:Lipids