Strong association between idiopathic membranous nephropathy and HLA-DRW3.
HLA A, B, and DR antigens were determined in a homogeneous group of patients with idiopathic membranous nephropathy. The frequency of HLA-DRW3 was significantly higher in the patients than in a control population. The frequencies of HLA B8 and B18, which are in linkage disequilibrium with DRW3, were also increased.
D000293:Adolescent; D000328:Adult; D000368:Aged; D019867:Anti-Glomerular Basement Membrane Disease / Q000209:etiology / Q000235:genetics / Q000276:immunology*; D005260:Female; D006680:HLA Antigens / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007105:Immune Complex Diseases / Q000276:immunology*; D008297:Male; D008875:Middle Aged
D006680:HLA Antigens