title: Karyotype 45, XX, --11,2q+ of bone marrow cells in a case of di Guglielmo syndrome.
abstract: The case of 50-years-old woman with the chronic type of erythraemia (di Guglielmo syndrome) and the karyotype 45, XX, --11,2q+ of bone marrow cells is described. By means of G-banding the karyotype 45,XX, -2, -11, + der (2), t(2;11) (2pter leads to 2qter:: 11q12 leads to 11qter) was established. The karyotype of bone marrow was thus partically monosomic for chromosome No. 11, for its segment 11 (pter leads to q11).
mesh_terms: D002869:Chromosome Aberrations; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007621:Karyotyping; D004915:Leukemia, Erythroblastic, Acute / Q000235:genetics*; D008875:Middle Aged