Isolation and characterization of soluble epidermal antigens reactive with pemphigus antibodies.
The antigenic substance reactive with pemphigus antibodies was isolated from the soluble component of guinea pig epidermis by affinity chromatography. The substance was a protein of molecular weight 18 000 and consisted of RNA and hexose.
D000818:Animals; D000937:Antigen-Antibody Reactions; D000941:Antigens / Q000032:analysis / Q000302:isolation & purification*; D002241:Carbohydrates / Q000032:analysis; D002846:Chromatography, Affinity; D004247:DNA / Q000032:analysis; D000939:Epitopes; D005260:Female; D006168:Guinea Pigs; D008970:Molecular Weight; D010392:Pemphigus / Q000276:immunology*; D012313:RNA / Q000032:analysis; D012867:Skin / Q000276:immunology*
D000941:Antigens; D002241:Carbohydrates; D000939:Epitopes; D012313:RNA; D004247:DNA