title: Treatment of cystic ovarian disease in dairy cattle. Comparative observation of the effects of an intramuscular injection of corticosteroids and an intravenous injection of a combination of human chorionic gonadotropin and progesterone.
abstract: Of 67 cows with cystic ovarian disease (COD), 34 were injected intramuscularly with 20 mg of betamethasone of 10 mg of dexamethasone (CC) and 33 intravenously with a combination of 3,000 IU of human chorionic gonadotropin and 125 mg of progesterone (HCG -P). Pregnancy rates and intervals between treatment and conception were 32.4% and 32.1 +/- 30.5 days, respectively, in the CC-treated cows and 30.3% and 51.6 +/- 29.5 days in the HCG -P-treated ones. Cows which had not responded to gonadotropin treatment showed a considerably higher pregnancy rate when treated with CC and a lower pregnancy rate when administered with HCG -P than those which had received no treatment before. There was a trend that the earlier a cow was treated, the more readily she recovered. CC injection gave a satisfactory result even when performed long after calving. The estrous behaviour seemed to be related with prognosis in cows with COD. In both CC-treated and HCG -P-treated cows, the pregnancy rate was the highest in cows showing anestrus and the lowest in those exhibiting irregular estrus.
mesh_terms: D000818:Animals; D001623:Betamethasone / Q000008:administration & dosage / Q000627:therapeutic use; D002417:Cattle / Q000502:physiology; D002418:Cattle Diseases / Q000188:drug therapy*; D006063:Chorionic Gonadotropin / Q000008:administration & dosage / Q000627:therapeutic use*; D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use; D004971:Estrus; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D007273:Injections, Intramuscular; D007315:Insemination, Artificial / Q000662:veterinary; D010048:Ovarian Cysts / Q000188:drug therapy / Q000662:veterinary*; D011247:Pregnancy; D011374:Progesterone / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D006063:Chorionic Gonadotropin; D005938:Glucocorticoids; D011374:Progesterone; D003907:Dexamethasone; D001623:Betamethasone