Killing of intraphagocytic Staphylococcus aureus by dihydrostreptomycin entrapped within liposomes.
Liposomes (phospholipid vesicles) may serve as vehicles of antibiotic transport to intracellular sites. Liposomes containing entrapped dihydrostreptomycin enhanced killing of Staphylococcus aureus contained within phagocytic vacuoles.
D000818:Animals; D004096:Dihydrostreptomycin Sulfate / Q000008:administration & dosage / Q000494:pharmacology*; D066298:In Vitro Techniques; D008081:Liposomes; D008264:Macrophages / Q000187:drug effects / Q000382:microbiology; D051379:Mice; D010587:Phagocytosis / Q000187:drug effects*; D013211:Staphylococcus aureus / Q000187:drug effects*
D008081:Liposomes; D004096:Dihydrostreptomycin Sulfate