Evidence for an absence of cross-reactivity between the human beta2-microblobulin and human IgG allotypes and subclasses.
Six beta2-microglobulins were isolated from the urine of six patients with renal tubular dysfunction. Cross-reactivity between these beta2-microglobulins and antigenic determinants of different IgG allotypes and subclasses was investigated. No evidence of cross-reactivity was found. Some hypotheses are discussed concerning these results.
D000595:Amino Acid Sequence; D001609:Beta-Globulins / Q000276:immunology*; D003429:Cross Reactions; D000939:Epitopes; D006386:Hemagglutination Tests; D006801:Humans; D007126:Immunoglobulin Allotypes; D007074:Immunoglobulin G; D001613:beta 2-Microglobulin / Q000276:immunology* / Q000652:urine
D001609:Beta-Globulins; D000939:Epitopes; D007126:Immunoglobulin Allotypes; D007074:Immunoglobulin G; D001613:beta 2-Microglobulin