title: [Treatment of diffuse toxic goiter with radioactive iodine in combination with prolonged antithyroid therapy].
abstract: The authors analyzed clinically the results of treatment of 237 patients with diffuse toxic goiter with radioactive iodine in combination with prolonged antithyroidal therapy (12--18 months). The advantages of combined therapy consisted in the use of relatively low 131I doses, a great frequensy of clinical remissions of thyrotoxicosis (83%), in the absence of thyrotoxicosis remissions after the administration of a low radioactive iodine dose and a low percentage of stable hypothyroidism development (0.8%) as a complication of radioiodine therapy.
mesh_terms: D000328:Adult; D000368:Aged; D013956:Antithyroid Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D006111:Graves Disease / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008713:Methimazole / Q000008:administration & dosage; D008875:Middle Aged; D011879:Radiotherapy Dosage; D013960:Thyroid Function Tests; D013997:Time Factors
chemical_list: D013956:Antithyroid Agents; D007457:Iodine Radioisotopes; D008713:Methimazole
vernacular_title: Lechenie bol'nykh diffuznym toksicheskim zobom radioaktivnym ĭodom v sochetanii s dlitel'noĭ antitireoidnoĭ terapieĭ.