Inhibition of oxidation by peroxidase of human serum proteins.
The oxidation of essential serum proteins, albumin and gamma globulin, by the enzyme peroxidase can be partially inhibited by compounds, such as EDTA and 2,4-pentanedione, that complex with the iron ion in peroxidase. The importance of such inhibition lies in the circumstance that the oxidations in question might be a possible causative factor in tissue aging.
D000096:Acetone / Q000031:analogs & derivatives; D000375:Aging; D000975:Antioxidants; D001798:Blood Proteins; D004492:Edetic Acid; D006801:Humans; D066298:In Vitro Techniques; D010544:Peroxidases / Q000037:antagonists & inhibitors*; D012709:Serum Albumin; D005719:gamma-Globulins
D000975:Antioxidants; D001798:Blood Proteins; D012709:Serum Albumin; D005719:gamma-Globulins; D000096:Acetone; D004492:Edetic Acid; D010544:Peroxidases