Serial measurement of beta2 microglobulin, acute phase reactant proteins and the ESR in non-Hodgkin's lymphomas and chronic lymphocytic leukaemia.
Long-term observation of non-Hodgkin's lymphomas indicates they can be sub-divided into two groups with respect to changes in the plasma proteins. The first group has acute phase reactant proteins raised during active disease and sometimes a raised B2m, whilst in remission the protein profile is normal. The second group is typified by a chronic elevation of B2m and ESR but has normal C-RP levels. Chronic lymphocytic leukaemia usually has a raised B2 m level and normal acute phase proteins, a subset with low B2 m is described.
D000328:Adult; D000368:Aged; D001609:Beta-Globulins / Q000032:analysis*; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis*; D005260:Female; D005500:Follow-Up Studies; D006023:Glycoproteins / Q000097:blood; D006801:Humans; D007945:Leukemia, Lymphoid / Q000097:blood*; D008223:Lymphoma / Q000097:blood*; D008297:Male; D008875:Middle Aged; D001613:beta 2-Microglobulin / Q000032:analysis*
D001609:Beta-Globulins; D006023:Glycoproteins; D001613:beta 2-Microglobulin; D002097:C-Reactive Protein