title: [Textile pest control in textile stores with a combination preparation of methoxycholor and chlorpyrifos [0,0-diethyl-(3,5,6-trichloro-2-pyridyl)-monothiophosphate]].
abstract: The effect on man of a mixture of methoxyclorine and 0,0-diethyl-(o8k8l-trichloro-2-pyridyl)-monothiophosphate (chlorpyrifos) used for textile pest control in poorly ventilated textile storages were examined under realistic test conditions. The chronical exposure of the test persons to chlorpyrifos, although originally thought to be of a negligible order, surprisingly resulted in an approximately 40% inhibition of the serum chlinesterase (ChE) without any significant spontaneous recovery of the ChE activity in three out of four test subjects during the test period. On the contrary, the activity of the acetylcholinesterase of the erythrocytes (AChE), after a temporary insignificant decrease, was found to be considerable increased for the duration of the test. As a result of these examinations it is recommended not to use insecticides containing alkylphosphates for textile pest control in poorly ventilated reeom if an exposure of man during the desorption phase cannot be excluded.
mesh_terms: D000110:Acetylcholinesterase / Q000097:blood; D000328:Adult; D004390:Chlorpyrifos / Q000633:toxicity*; D002800:Cholinesterase Inhibitors / Q000097:blood; D004781:Environmental Exposure; D004912:Erythrocytes / Q000187:drug effects / Q000201:enzymology; D006801:Humans; D008731:Methoxychlor / Q000633:toxicity*; D008875:Middle Aged; D013783:Textile Industry; D013997:Time Factors
chemical_list: D002800:Cholinesterase Inhibitors; D000110:Acetylcholinesterase; D004390:Chlorpyrifos; D008731:Methoxychlor
vernacular_title: Zur Frage der Textilschädlingsbekämpfung in Textillagern mit einem Kombinationspräparat aus Methoxychlor und Chlorpyfifos [0,0-Di9athyl-(3,5,6-trichlor-2-pyridyl)-monothiophosphat]