title: Changes in hospital antibiotic therapy after a quality-of-use study.
abstract: During the first quarters of 1976 and 1977, the use of parenteral gentamicin, cloxacillin, ampicillin, and cephalothin was surveyed in 219 (in 1976) and 240 (in 1977) patients admitted to a surgical, a gynaecological, and a medical ward of a teaching hospital. In 1976, therapy was assessed as irrational in 42%, 50%, and 12% of the surgical, gynaecological, and medical patients, respectively; the corresponding figures for 1977 were 24%, 25%, and 22%. The more rational therapy in 1977 was due to a shorter duration of prophylactic therapy; and to fewer patients receiving oral antibiotics just before or after the parenteral antibiotic.
mesh_terms: D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002512:Cephalothin / Q000627:therapeutic use; D003023:Cloxacillin / Q000627:therapeutic use; D004341:Drug Evaluation; D004363:Drug Utilization; D005260:Female; D005831:Genital Diseases, Female / Q000628:therapy; D005839:Gentamicins / Q000627:therapeutic use; D006784:Hospitals, Teaching; D006801:Humans; D008510:Medication Systems, Hospital; D009864:Ontario; D011786:Quality Control; D013530:Surgical Wound Infection / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins; D000667:Ampicillin; D003023:Cloxacillin; D002512:Cephalothin