title: The cumulative inhibitory effect of repetitively flashed stimuli on the recovery process of the human visual evoked potential to a test stimulus.
abstract: Cumulative inhibitory effects produced by visual response to flashed conditioning stimuli were measured by means of the amplitude reduction of the visual evoked potential (VEP) to a test stimulus. Four kinds of conditioning stimuli were used: a single conditioning stimulus and 3 repetitive conditioning stimuli with interstimulus intervals (ISIs) of 100, 200 and 400 msec, respectively. The VEP amplitude for the test stimulus was reduced most when the stimulus was paired with the single conditioning stimulus. It still remained small when the test stimulus was paired with the repetitive conditioning stimulus of 400 msec ISI, increased significantly when the ISI was shortened from 400 to 200 msec. Explanations of the VEP behaviors in terms of the stimulus relevance, task difficulty and the recovery rate of the cortical excitability were discussed.
mesh_terms: D000328:Adult; D003213:Conditioning, Psychological / Q000502:physiology*; D004569:Electroencephalography; D004585:Electrooculography; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D010775:Photic Stimulation; D014785:Vision, Ocular / Q000502:physiology*