Antibodies to bacterial L-asparaginases.
Complement fixation has been shown to occur when asparaginase reacts with specific antibody. This is as a result of an antigenic determinant common to the four bacterial asparaginases. Patients on asparaginase therapy may produce antibodies and these could be demonstrated by complement fixation.
D000293:Adolescent; D000328:Adult; D000906:Antibodies; D001215:Asparaginase / Q000276:immunology*; D002861:Chromobacterium / Q000201:enzymology; D003168:Complement Fixation Tests; D003429:Cross Reactions; D004755:Enterobacteriaceae / Q000201:enzymology; D000939:Epitopes; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D000906:Antibodies; D000939:Epitopes; D001215:Asparaginase