[Cation preferences of the DNA-polymerases in plasma from patients with leukaemia or breast cancer (author's transl)].
The reverse transcriptase in plasma from leukaemic patients perfers the divalent cation Mn++ to Mg++ in the polymerase assay. The reverse is true for the enzyme from plasma of patients with breast cancer. This cation preference is analogous to the cation preference found in B- and C-type RNA-tumour viruses.
D001943:Breast Neoplasms / Q000201:enzymology*; D002413:Cations, Divalent; D003429:Cross Reactions; D005260:Female; D006801:Humans; D007181:Inclusion Bodies, Viral; D007938:Leukemia / Q000201:enzymology*; D008274:Magnesium; D008345:Manganese; D011289:Preleukemia / Q000201:enzymology; D012194:RNA-Directed DNA Polymerase / Q000097:blood*
D002413:Cations, Divalent; D008345:Manganese; D012194:RNA-Directed DNA Polymerase; D008274:Magnesium
Kationenpreferenzen der reversen Transkriptasen im Plasma von Patienten mit Mammakarziom oder Leukämie