[Lymphocyte membrane receptors mediating recognition of antigens (author's transl)].
The present article summarizes briefly our knowledge of antigen-specific B- and T-lymphocyte receptors. Antigen-specific receptors on mammalian B-lymphocytes are mainly monomeric IgM and IgD consisting of conventional immunoglobulin heavy and light chains. The nature of the T-lymphocyte receptors which can specifically recognize antigens is not yet fully defined but it seems that conventional light chains do not participate in the build up of this receptor. However, T-lymphocytes express two polypeptide chains which bear variable domains sharing idiotypic determinants with the corresponding B-lymphocytes. These Tau chains can bind the corresponding antigen.
D000917:Antibody Formation; D000918:Antibody Specificity; D001402:B-Lymphocytes / Q000276:immunology*; D001666:Binding Sites, Antibody; D000939:Epitopes; D006801:Humans; D007143:Immunoglobulin Heavy Chains; D008213:Lymphocyte Activation; D011947:Receptors, Antigen, B-Cell; D013601:T-Lymphocytes / Q000276:immunology*
D000939:Epitopes; D007143:Immunoglobulin Heavy Chains; D011947:Receptors, Antigen, B-Cell
Membranrezeptoren lymphatischer Zellen in der Informationsübermittlung antigener Reize.