Prenatal detection of the 47, XYY karyotype.
The ethical decisions involved before and after the prenatal diagnosis of a 47, XYY karyotype in the fetus of a 32-year-old woman are discussed. It was decided that the parents should be presented with all the known facts about XYY-associated abnormalities and allowed to choose whether pregnancy should continue; the physician's role would be to support them in their decision and help them carry it out.
D000328:Adult; D000649:Amniocentesis; D000653:Amniotic Fluid / Q000166:cytology*; D003657:Decision Making; D030881:Disclosure; D004992:Ethics, Medical; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012729:Sex Chromosome Aberrations / Q000175:diagnosis*; D014997:XYY Karyotype / Q000175:diagnosis*