title: [Agammaglobulinemia and hypogammaglobulinemia in newborn lambs depending on the time of the first suckling].
abstract: Studied were the agammaglobulinemia and the hypogammaglobulinemia in 120 newborn lambs of which 100 had sucked for the first time at the first hour following birth, 10 had sucked at the ninth hour, and the remaining 10--at the 24th hour. Blood was sampled at the 1st, 2nd, 3rd, 5th, 10th, 24th, and 48th hour, and was immunoelectrophoretically studied after Grabar. Precipitation was done with hyperimmune antiovine gammaglobulin serum. Part of the lambs with agammaglobulinemia were killed and the small intestine was used to prepare extracts for an immunoelectrophoretic study after Grabar and for establishing gammaglobulins. It was found that lambs that had first sucked at the 1st hour following birth the resorption of the colostral gammaglobulin at the various hours later on varied. In the blood serum of 40% of the investigated lambs at the 1st hour there were gammaglobulins; gammaglobulins in 96% of the animals at the 24th hour after they had first sucked. A delayed first sucking after birth--at the 10th and 24th hour--led to hypo- and agammaglobulinemia. In the blood of such lambs at the 48th hour after sucking the gammaglobulins were 0.70 and 0.95 g% less as against the amount of gammaglobulins in lambs that had sucked for the first time at the first hour after birth.
mesh_terms: D000361:Agammaglobulinemia / Q000662:veterinary*; D000818:Animals; D000831:Animals, Newborn; D000833:Animals, Suckling; D012756:Sheep; D012757:Sheep Diseases / Q000097:blood / Q000209:etiology*; D013997:Time Factors; D005719:gamma-Globulins / Q000032:analysis
chemical_list: D005719:gamma-Globulins
vernacular_title: Prouchvane agamaglobulinemiiata i khipogamaglobulinemiiata pri novorodeni agneta v zavisimost ot vremeto na purvoto zabozavane.