Upper gastrointestinal haemorrhage in hepatic cirrhosis: causes and relation to hepatic failure and stress.
Emergency fibroscopy revealed bleeding lesions in 84 cirrhotic patients. In patients with moderate or no hepatic failure, the commonest actively bleeding sources were oesophagogastric varices and acute mucosal ulcers associated with the ingestion of anti-inflammatory drugs. In patients with severe hepatic failure, acute mucosal ulcers unrelated to drugs predominated and there was evidence that these were stress-induced erosions.
D000208:Acute Disease; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D000328:Adult; D000368:Aged; D001241:Aspirin / Q000009:adverse effects; D002908:Chronic Disease; D004932:Esophageal and Gastric Varices / Q000150:complications; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000139:chemically induced / Q000150:complications / Q000209:etiology; D010438:Peptic Ulcer Hemorrhage / Q000209:etiology; D012422:Rupture, Spontaneous; D013312:Stress, Physiological / Q000150:complications*
D000305:Adrenal Cortex Hormones; D001241:Aspirin