title: Isolation of mouse C-reactive protein from liver and serum.
abstract: Purified proteins have been isolated from the sera and livers of mice. These proteins are antigenically identical but share antigenic determinants in common with human C-reactive protein and do not share antigenic determinants in common with mouse or human immunoglobulins. The proteins interact with C-polysaccharide, are precipitated by calcium ions, migrate electrophoretically with gamma mobilities, and have isoelectric points of 4.8 and 5.62. Since these properties are characteristic of C-reactive protein of man, monkey, rabbit and dog, the pure proteins isolated from mice are designated mouse C-reactive protein.
mesh_terms: D000818:Animals; D002097:C-Reactive Protein / Q000276:immunology / Q000302:isolation & purification*; D003429:Cross Reactions; D000939:Epitopes; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007525:Isoelectric Focusing; D008099:Liver / Q000032:analysis*; D051379:Mice; D008810:Mice, Inbred C57BL / Q000276:immunology; D013045:Species Specificity
chemical_list: D000939:Epitopes; D002097:C-Reactive Protein