Levamisole in the treatment of Crohn's disease.
In 8 patients with active uncomplicated Crohn's disease who were not receiving any specific therapy, a clinical remission was induced with an elemental diet, and then an attempt was made to maintain this remission with levamisole. This regimen resulted in excellent control of the disease. A drug-induced arthritis developed in two patients and resolved spontaneously. There were no other significant side-effects.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001799:Blood Sedimentation; D001835:Body Weight; D002784:Cholesterol / Q000097:blood; D003424:Crohn Disease / Q000178:diet therapy / Q000188:drug therapy* / Q000378:metabolism; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012075:Remission, Spontaneous; D012709:Serum Albumin / Q000032:analysis
D006454:Hemoglobins; D012709:Serum Albumin; D007978:Levamisole; D002784:Cholesterol