Follow-up study of myasthenic children after thymectomy.
The results of thymectomy of 28 myasthenic children observed from 1 to 9 years after operation are discussed. Improvement was obtained in 19 cases (67.8%), with full remission in 12 cases (42.8%). Six children died. No correlation was found between the results of thymectomy and the duration of the disease, sex or histological findings in the thymus. No increase of incidence or severity of infections were observed in thymectomized children. Caution is recommended regarding vaccination of myasthenic children.
D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009157:Myasthenia Gravis / Q000150:complications / Q000473:pathology / Q000628:therapy*; D013934:Thymectomy; D013945:Thymoma / Q000150:complications; D013950:Thymus Gland / Q000473:pathology; D013952:Thymus Hyperplasia / Q000150:complications; D013953:Thymus Neoplasms / Q000150:complications; D014611:Vaccination / Q000009:adverse effects