Serum alpha-fetroprotein concentration in adult patients under corticoid, estroprogestative or androgen therapy.
The serum alpha-fetoprotein concentration was measured by radioimmunoassy in 41 women with or without hormonal contraception, 21 patients with rheumatoid arthritis given corticosteroids or not, and 6 patients under androgen therapy for aplastic anemia. None of these therapies induced any significant variation of the serum alpha-fetoprotein level. More extensive studies are needed to investigate the possible effect of these hormones on the metabolism of this protein at a cellular level.
D000328:Adult; D000741:Anemia, Aplastic / Q000188:drug therapy; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D006728:Hormones / Q000627:therapeutic use*; D006801:Humans; D008710:Methenolone / Q000627:therapeutic use; D008775:Methylprednisolone / Q000627:therapeutic use; D011374:Progesterone / Q000627:therapeutic use; D000509:alpha-Fetoproteins / Q000032:analysis
D004967:Estrogens; D006728:Hormones; D000509:alpha-Fetoproteins; D011374:Progesterone; D008710:Methenolone; D008775:Methylprednisolone