title: Aortocoronary bypass grafting in the management of patients with coronary artery disease.
abstract: There is widespread agreement that aortocoronary bypass grafting generally lessens the symptoms and functional limitations of patients with angina pectoris. Evidence for prolongation of life or prevention of myocardial infarction, arrhythmias and ventricular dysfunction is inconclusive. Harmful effects associated with surgical management of coronary artery disease can be documented in terms of operative mortality, perioperative myocardial infarction, graft occlusion and progression of occlusive disease in the native circulation. In this review of published experience, the accomplishments and the limitations of myocardial revascularization are considered in various clinical settings. Critical assessment of evolving information leads to the conclusion that widespread application of this procedure beyond the alleviation of symptoms refractory to medical therapy is not justified by present data.
mesh_terms: D000787:Angina Pectoris / Q000601:surgery; D001145:Arrhythmias, Cardiac / Q000601:surgery; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000401:mortality; D003327:Coronary Disease / Q000601:surgery*; D005260:Female; D006322:Heart Aneurysm / Q000601:surgery; D006333:Heart Failure / Q000601:surgery; D006349:Heart Valve Diseases / Q000601:surgery; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000601:surgery; D010166:Palliative Care; D012770:Shock, Cardiogenic / Q000601:surgery