Lack of dermal changes in uninvolved skin after photochemotherapy of psoriasis: biochemical studies.
Low Hyp and Hyl values were found in psoriatic lesions. Treatment with PUVA achieved a return to normal values. No effect of PUVA on the collagen of uninvolved skin of psoriatic patients could be demonstrated after 4 months. There were no age-related differences in the content of Hyp and Hyl between samples of uninvolved skin of psoriatics.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D003094:Collagen / Q000378:metabolism* / Q000528:radiation effects; D005260:Female; D006801:Humans; D006901:Hydroxylysine / Q000378:metabolism*; D006909:Hydroxyproline / Q000378:metabolism*; D008297:Male; D008730:Methoxsalen / Q000009:adverse effects*; D008875:Middle Aged; D010778:Photochemotherapy / Q000009:adverse effects*; D011565:Psoriasis / Q000188:drug therapy* / Q000378:metabolism; D012867:Skin / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D013997:Time Factors
D006901:Hydroxylysine; D003094:Collagen; D006909:Hydroxyproline; D008730:Methoxsalen