title: Differentiation of thyrotoxicosis induced by thyroid destruction from Graves' disease.
abstract: Thyroid function was tested in untreated patients with Graves' disease or thyrotoxic subacute thyroiditis, and in patients with autoimmune thyroiditis who showed postpartum or spontaneous transient thyrotoxicosis. The serum triiodothyronine/thyroxine ratio (T3/T4) was greater than 20 ng/microgram in Graves' disease but less than 20 in all patients with subacute thyroiditis and 9 of 11 patients with autoimmune thyroiditis. Thus, like radioactive iodine uptake, the serum T3/T4 ratio is useful for differentiating destruction-induced thyrotoxicosis from the stimulation-induced hyperthyroidism of Graves' disease.
mesh_terms: D000328:Adult; D001327:Autoimmune Diseases / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006111:Graves Disease / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D006980:Hyperthyroidism / Q000175:diagnosis* / Q000209:etiology; D007457:Iodine Radioisotopes; D008875:Middle Aged; D011247:Pregnancy; D011644:Puerperal Disorders / Q000175:diagnosis; D013960:Thyroid Function Tests; D013966:Thyroiditis / Q000175:diagnosis; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D007457:Iodine Radioisotopes; D014284:Triiodothyronine; D013974:Thyroxine