title: Influence of boar acrosin antibodies produced in rabbit and sheep on chymotrypsinogen activation catalyzed by acrosin from boar, bull, ram, rabbkt and human.
abstract: Activation of bovine chymotrypsinogen is catalyzed with increasing velocity by human, rabbit, boar, bull and ram acrosin. Antiboar-acrosin rabbit gamma-globulins cause a significant reduction in the proenzyme activation rate induced by boar and bull acrosin, but only a weak reduction or none if ram or rabbit acrosin is the activating agent. The antiboar-acrosin gamma-globulins from sheep strongly inhibit chymotrypsinogen activation by ram, bull and boar acrosin, and significantly inhibit the human acrosin-catalyzed reaction.
mesh_terms: D000176:Acrosin / Q000276:immunology* / Q000494:pharmacology; D000818:Animals; D000906:Antibodies; D000918:Antibody Specificity; D002417:Cattle; D002919:Chymotrypsinogen / Q000378:metabolism*; D010450:Endopeptidases / Q000276:immunology*; D004789:Enzyme Activation; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D066298:In Vitro Techniques; D008297:Male; D011817:Rabbits; D012756:Sheep; D013045:Species Specificity; D013552:Swine; D014361:Trypsin Inhibitors; D005719:gamma-Globulins / Q000494:pharmacology
chemical_list: D000906:Antibodies; D007074:Immunoglobulin G; D014361:Trypsin Inhibitors; D005719:gamma-Globulins; D002919:Chymotrypsinogen; D010450:Endopeptidases; D000176:Acrosin