Small-intestinal mucosal antibodies against antigens of non-pathogenic luminal or mucosal bacteria in young children with and without diarrhoea.
Duodenal mucosal antibody against non-pathogenic bacteria, grown either from the luminal juices or the mucosa itself, was demonstrated for the first time in 7 of 8 children with diarrhoea and only 2 of 7 without diarrhoea. Neither group showed significant histological abnormalities on duodenal biopsy. An aetiological relation between the antibody and the persistence of postenteritis diarrhoea is possible.
D000907:Antibodies, Bacterial / Q000302:isolation & purification*; D000937:Antigen-Antibody Reactions; D000942:Antigens, Bacterial; D001419:Bacteria / Q000276:immunology*; D002675:Child, Preschool; D002908:Chronic Disease; D003968:Diarrhea, Infantile / Q000209:etiology / Q000276:immunology* / Q000382:microbiology; D004386:Duodenum / Q000276:immunology* / Q000382:microbiology; D004751:Enteritis / Q000150:complications; D005260:Female; D006801:Humans; D007223:Infant; D007413:Intestinal Mucosa / Q000276:immunology*; D007419:Intestinal Secretions / Q000276:immunology; D008297:Male
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial