title: Classification of rotaviruses: report from the World Health Organization/Food and Agriculture Organization Comparative Virology Program.
abstract: The Reoviridae working team was established under the World Health Organization/Food and Agriculture Organization Comparative Virology Program in 1975. The generic name rotavirus has been adopted for the reovirus-like agents associated with diarrhea in man and animals, and the Nebraska calf diarrheal virus strain of bovine rotavirus has been selected as a candidate reference virus. Stocks of this virus and of gnotobiotic calf antiserum have been prepared. Antigenic differences among rotaviruses isolated from different species were recognized on the basis of virus-neutralization tests; a possible association between antigen specificity and variation in the RNA segments and structural proteins of rotaviruses was noticed.
mesh_terms: D000956:Antigens, Viral / Q000032:analysis; D000939:Epitopes; D006077:Government Agencies; D008970:Molecular Weight; D012328:RNA Viruses / Q000145:classification*; D012367:RNA, Viral / Q000032:analysis; D012401:Rotavirus / Q000032:analysis / Q000145:classification* / Q000276:immunology; D014944:World Health Organization
chemical_list: D000956:Antigens, Viral; D000939:Epitopes; D012367:RNA, Viral