Increased frequency of HLA-DRW4 in chronic active hepatitis.
HLA-A, B, C and DRw typing was performed on peripheral blood lymphocytes of 17 adults with the diagnosis of chronic active hepatitis made by liver biopsy as the only criterion for study. An increase in the frequency of HLA-DRw4 (71 vs. 24%, p less than 0.005) was observed, but there was no increased frequency of HLA-A1, B8 or any other HLA locus specificity.
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D000939:Epitopes; D005260:Female; D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D006505:Hepatitis / Q000235:genetics* / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged
D000939:Epitopes; D006680:HLA Antigens