Histamine release in dogs by Emulphor EL620.
A vehicle containing ethanol and Emulphor EL620 lowers blood pressure and increases heart rate in morphine-chloralose anesthetized dogs. These effects are associated with histamine release caused by Emulphor EL620.
D000777:Anesthetics; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004285:Dogs; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006632:Histamine / Q000097:blood; D006636:Histamine Release / Q000187:drug effects*; D008297:Male; D009020:Morphine; D009821:Oils / Q000494:pharmacology*; D010424:Pentobarbital
D000777:Anesthetics; D009821:Oils; D009020:Morphine; D006632:Histamine; D010424:Pentobarbital