[Detection and prognostic significance of Ag "e" and its antibody in the course of HB virus infections[].
A new antigen antibody system the e Ag and Ab has been investigated by immunodiffusion and counterelectrophoresis in the serum of 509 subjects. Those included 242 patients with polyarteritis, acute chronic or fulminant hepatitis; 85 hemodialysis HBs Ag carriers and 182 asymptomatic HBs Ag carrier blood donors. Neither e Ag nor anti- e were detected in any of the non hepatitis B virus associated cases. Counterelectrophoresis was found to be more sensitive than immunodiffusion and detected either e Ag or anti- e in 24 p. cent more cases. e Ag was found among HBs Ag positive patients with polyarteritis, chronic hepatitis or under going hemodialysis. Anti- e was observed in 28 p. cent to 66 p. cent of asymptomatic HBs Ag carriers. The study of the nature and prognostic significance of e Ag and anti- e appear of major importance in the understanding and follow up of HB virus infections.
D000914:Antibodies, Viral / Q000032:analysis; D000936:Antigen-Antibody Complex; D001782:Blood Donors; D003378:Counterimmunoelectrophoresis; D000939:Epitopes; D006505:Hepatitis / Q000276:immunology; D006801:Humans; D005779:Immunodiffusion; D010488:Polyarteritis Nodosa / Q000276:immunology; D006435:Renal Dialysis
D000914:Antibodies, Viral; D000936:Antigen-Antibody Complex; D000939:Epitopes
Détection et signification pronostique de l'Ag "e" et de son anticorps au cours des infections à virus HB