title: Carcinogenic action of polycyclic hydrocarbons in animals and in man.
abstract: Basic data on the carcinogenic action of polycyclic aromatic hydrocarbons (PAH) in animals and in man are presented, mainly from the author's own experience. Benzo[a]pyrene (BaP), a powerful carcinogenic agent widely spread in the human environment, can be considered an indicator of PAH. Quantitative spectral-fluorescent methods developed by the author and his co-workers were used to study the circulation of BaP in the atmosphere, hydrosphere, soil, plants, animals and humans. Accumulation and degradation of PAH, as well as the background level of BaP, in the environment are described. The results were used as a basis for establishing health standards and other preventive measures against cancer.
mesh_terms: D000393:Air Pollutants / Q000633:toxicity; D000395:Air Pollutants, Occupational / Q000633:toxicity; D000397:Air Pollution; D000401:Aircraft; D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism / Q000633:toxicity; D002274:Carcinogens, Environmental / Q000633:toxicity*; D006801:Humans; D008452:Maximum Allowable Concentration; D009369:Neoplasms / Q000139:chemically induced; D010578:Petroleum / Q000633:toxicity; D011083:Polycyclic Compounds / Q000633:toxicity*; D011230:Precancerous Conditions / Q000139:chemically induced; D012988:Soil Microbiology; D012989:Soil Pollutants / Q000633:toxicity; D001335:Vehicle Emissions / Q000633:toxicity; D014874:Water Pollutants, Chemical / Q000633:toxicity
chemical_list: D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D001580:Benzopyrenes; D002274:Carcinogens, Environmental; D010578:Petroleum; D011083:Polycyclic Compounds; D012989:Soil Pollutants; D001335:Vehicle Emissions; D014874:Water Pollutants, Chemical