title: An animal model for the growth of human tumor cell lines.
abstract: Newborn rats were thymectomized at less than 24 hr of age and received antilymphocyte serum and heterologous human tumor cells. This model allows the growth of large primary tumors with a high metastatic percentage. This model may be applicable to the study of a wide variety of genitourinary tumors.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000961:Antilymphocyte Serum; D002295:Carcinoma, Transitional Cell / Q000473:pathology; D002460:Cell Line; D004195:Disease Models, Animal; D006801:Humans; D066298:In Vitro Techniques; D008175:Lung Neoplasms / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000473:pathology*; D011470:Prostatic Hyperplasia / Q000473:pathology; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew; D013934:Thymectomy; D014183:Transplantation, Heterologous; D001749:Urinary Bladder Neoplasms / Q000473:pathology
chemical_list: D000961:Antilymphocyte Serum