alpha1-Antichymotrypsin interaction with cationic proteins from granulocytes.
Human granulocytes contain cationic proteins with chymotrypsin-like activity. These proteases showed a higher relative affinity for alpha1-antichymotrypsin than for alpha1-antitrypsin but the highest affinity for alpha2-macroglobulin. The complexes between cationic protein and alpha1-antichymotrypsin migrate as beta-globulin on agarose gel electrophoresis.
D002918:Chymotrypsin / Q000037:antagonists & inhibitors* / Q000097:blood / Q000276:immunology; D006098:Granulocytes / Q000201:enzymology*; D006801:Humans; D007123:Immunoelectrophoresis, Two-Dimensional; D007700:Kinetics; D007962:Leukocytes / Q000201:enzymology*; D010447:Peptide Hydrolases / Q000097:blood*; D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins
D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins; D010447:Peptide Hydrolases; D002918:Chymotrypsin