Disopyramide--an effective treatment for lignocaine resistant ventricular dysrhythmias.
Intravenous disopyramide was used in 13 patients who developed recurrent ventricular dysrhythmias despite initial treatment with intravenous lignocaine after admission to the Coronary Care Unit of a busy district hospital. This was effective in 8 of the 13 patients treated and there was no major side effects observed. Disopyramide has the advantage of being available both as an oral and an intravenous preparation and is a useful drug to be added to the list of more conventional anti-dysrhythmic agents.
D001145:Arrhythmias, Cardiac / Q000150:complications / Q000188:drug therapy*; D005117:Cardiac Complexes, Premature / Q000150:complications; D004206:Disopyramide / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000627:therapeutic use*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications; D011725:Pyridines / Q000627:therapeutic use*; D013610:Tachycardia / Q000150:complications; D014693:Ventricular Fibrillation / Q000150:complications
D011725:Pyridines; D008012:Lidocaine; D004206:Disopyramide