[Effect of gold therapy in rheumatoid arthritis on leukopoiesis and granulocyte phagocytosis].
In 12 patients with rheumatoid arthritis the investigations of leukopoiesis and granulocytic phagocytosis were carried out before and after a gold therapy. A marked reduction of granulocytic phagocytosis could be observed here which decreased after the gold therapy, yet remained below the values of a normal collective. Partly contrary informations are discussed. The disturbance of the phagocytosis capacity of granulocytes may possibly be due to a rheumatic factor.
D000469:Alkaline Phosphatase / Q000097:blood; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D005260:Female; D006046:Gold / Q000627:therapeutic use*; D006098:Granulocytes / Q000187:drug effects; D006410:Hematopoiesis / Q000187:drug effects*; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010587:Phagocytosis / Q000187:drug effects*; D012217:Rheumatoid Factor; D013213:Starch
D006046:Gold; D013213:Starch; D012217:Rheumatoid Factor; D000469:Alkaline Phosphatase
Die Beeinflussung der Leukopoese und der Granulozytenphagozytose vor und nach Goldtherapie bei Rheumatoidarthritis