Acycloguanosine: antiviral activity in the rabbit cornea.
We describe experiments, using the multiple microinoculation technique, to produce superficial herpes simplex keratitis in the rabbit cornea, which showed a potent antiviral effect of acycloguanosine.
D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D006147:Guanine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D007065:Idoxuridine / Q000627:therapeutic use; D007635:Keratitis, Dendritic / Q000188:drug therapy*; D011817:Rabbits; D014271:Trifluridine / Q000627:therapeutic use; D014740:Vidarabine / Q000627:therapeutic use; D001084:Vidarabine Phosphate / Q000627:therapeutic use
D000998:Antiviral Agents; D001084:Vidarabine Phosphate; D006147:Guanine; D014740:Vidarabine; D007065:Idoxuridine; D014271:Trifluridine