Identification of a common antigen of herpes simplex virus bovine herpes mammillitis virus, and B virus.
In immunoelectrophoretic analyses one common antigen was demonstrated in antigen preparations from herpes simplex virus types 1- and 2- (HSV-1 and HSV-2), bovine herpes mammillitis (BHM) virus-, and B virus-infected cells solubilized by Triton X-100. The antigen was also demonstrated in solubilized purified HSV-1 and BHM virus. The common antigen was identified as antigen 11 of HSV-1 or HSV-2. Differences were found in the polypeptide composition of the related antigens when isolated from the four different herpesviruses, but a glycopolypeptide with a molecular weight of 125,000 was present in each of the four different antigen preparations, indicating that this polypeptide carried the common antigenic determinants.
D000956:Antigens, Viral / Q000032:analysis*; D000939:Epitopes; D006020:Glycopeptides / Q000032:analysis; D006564:Herpesviridae / Q000276:immunology*; D006568:Herpesvirus 1, Cercopithecine / Q000276:immunology*; D001911:Herpesvirus 2, Bovine / Q000276:immunology*; D007122:Immunoelectrophoresis; D008970:Molecular Weight; D010455:Peptides / Q000032:analysis; D018139:Simplexvirus / Q000276:immunology*
D000956:Antigens, Viral; D000939:Epitopes; D006020:Glycopeptides; D010455:Peptides