title: Phototoxic reaction to long-term low-dose administration of chlorpromazine in mice.
abstract: The mouse tail in vivo technique for the study of acute drug phototoxicity was tested in experiments involving prolonged administration of chlorpromazine and ultraviolet light. A phototoxic reaction was induced with lower combined doses of drug and radiation than was the case in single exposures.
mesh_terms: D000818:Animals; D002746:Chlorpromazine / Q000008:administration & dosage / Q000633:toxicity*; D004195:Disease Models, Animal; D004890:Erythema / Q000209:etiology; D005260:Female; D051379:Mice; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D013623:Tail; D013997:Time Factors; D014466:Ultraviolet Rays
chemical_list: D002746:Chlorpromazine