title: Batrachotoxin inhibits axonal transport without affecting membrane potential in single neurons of Aplysia californica.
abstract: Intrasomatic injection of 0.25 ng of batrachotoxin (BTX) caused no depolarization of giant cerebral neurons (GCN) of Aplysia californica within 4 hr at 23 degrees C. The amplitude of action potential and the input resistance were slightly and reversibly decreased. The same dose of BTX caused a 68% inhibition of fast axonal transport.
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001048:Aplysia; D001370:Axonal Transport / Q000187:drug effects*; D001369:Axons / Q000187:drug effects / Q000502:physiology*; D001496:Batrachotoxins / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects; D009474:Neurons / Q000187:drug effects / Q000502:physiology*
chemical_list: D001496:Batrachotoxins