Unsaturated vitamin B12 binding capacity and serum lysozyme activity during the marrow granulocytes reserve tests.
Unsaturated vitamin B12 binding capacity (UBBC) and serum lysozyme activity (LZM) were estimated durinng the endotoxin, prednisone and hydrocortisone marrow granulocyte reserve (MGR) pool tests. Our results showed, that no additional mechanism except the shift of MGR from marrow caused granulocytosis after typhoid vaccine administration. While the prednisone, when given orally diminished additionally the number of the physiologically destroyed neutrophils. The hydrocortisone, however, showed the results very similar to those obtained after typhoid vaccine adminstration. Thus the hydrocortisone test seems to be most useful. It gives as good information as typhoid vaccine test but does not show its side-effects.
D000380:Agranulocytosis / Q000139:chemically induced; D001854:Bone Marrow Cells; D006801:Humans; D006854:Hydrocortisone / Q000494:pharmacology; D009113:Muramidase / Q000097:blood*; D011241:Prednisone / Q000494:pharmacology; D014436:Typhoid-Paratyphoid Vaccines / Q000494:pharmacology; D014805:Vitamin B 12
D014436:Typhoid-Paratyphoid Vaccines; D009113:Muramidase; D014805:Vitamin B 12; D011241:Prednisone; D006854:Hydrocortisone