alpha-Fetoprotein in liver disease.
Ther serum concentration of alpha-fetoprotein (AFP) was measured by radio-immunoassay in 98 patients with liver disease including hepatoma, chronic active hepatitis, alcoholic cirrhosis, and acute virus B hepatitis. Raised AFP levels, above 30 ng/ml, were found in 87% of patients with acute viral hepatitis, in 82% of patients with primary liver cell carcinoma, in 58% with chronic active hepatitis and in 14% of patients with alcoholic cirrhosis. However, levels above 1 000 ng/ml were found only in patients with hepatoma and in acute viral hepatitis.
D000293:Adolescent; D000328:Adult; D001741:Black or African American; D000368:Aged; D001219:Aspartate Aminotransferases / Q000032:analysis; D044383:Black People; D006528:Carcinoma, Hepatocellular / Q000097:blood; D002908:Chronic Disease; D005260:Female; D006505:Hepatitis / Q000097:blood; D006515:Hepatitis B virus; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000097:blood; D008107:Liver Diseases / Q000097:blood*; D008113:Liver Neoplasms / Q000097:blood / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D044469:Racial Groups; D011863:Radioimmunoassay; D013019:South Africa; D044465:White People; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins; D001219:Aspartate Aminotransferases