title: [Histochemical reactions in the diagnosis of carcinoid of the gastrointestinal tract].
abstract: The comparative effectiveness of 6 histochemical reactions permitting to detect endocrine granules in cells of carcinoids in the gastrointestinal tract were studied. The most sensitive methods were found to include Grimelius argirophilic reaction, staining with toluidine blue after acidic hydrolysis (HCl-TB) and with lead hematoxyline (Pb-H). By these methods endocrine granules were found in all 29 carcinoids examined. A modification of Grimelius argirophilic reaction is described and recommendations for its application in diagnosis of carcinoids of the gastrointestinal tract, their emboli and micrometastases are given.
mesh_terms: D002276:Carcinoid Tumor / Q000175:diagnosis* / Q000378:metabolism; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D006652:Histological Techniques; D006801:Humans; D013194:Staining and Labeling
vernacular_title: Gistokhimicheskie reaktsii v diagnostike kartsinoidov zheludochno-kishechnogo trakta.