Experimental irradiation of human corpse skin with pulsed laser ray.
Irradiation of skin with one pulse of a neodymium laser with an emission energy of 940 to 2190 J and a density of 52,220 to 273,750 J/cm2 leads to the formation of damage with characteristic macroscopic and microscopic features. The injuries that appeared were funnel-shaped cavities up to 2 mm deep, from 2 to 8 mm in dimaeter, and with a crater-like rim 1 to 2 mm wide. Tissue on cross section was pinkish-brown, as a rule. Histologically, there were sharply defined signs of coagulative necrosis, and a typical, distinct, micromorphological picture was present that is characteristic of electric marking: nuclei and cells at all layers of the epithelium that were elongated into "brush" or "swirl" shapes, coagulation of the epithelium, the formation in it of honeycombed cavities, swelling, and detachment of the endothelium and vessels from the skin proper. Skin stained with black ink, iodine, hematoxylin, or eosin is damaged by laser ray more intensely than unstained.
D002102:Cadaver; D006801:Humans; D007834:Lasers / Q000009:adverse effects*; D012867:Skin / Q000293:injuries* / Q000473:pathology; D013194:Staining and Labeling