[Degeneration of the laminated corpuscles (of Vater--Pacini) following colchicine application to a nerve].
Laminated pacinian corpuscles from the cat mesentery have been studied morphologically and morphometrically after nerve section and colchicine application to the nerve and the results obtained are represented. Similar interventions in the nerve produce changes in the receptors resembling those of wallerian type degeneration, degeneration rate after sectioning being higher than after colchicine application. At early stages after colchicine application the internal cone and its nuclei increase in size. The data obtained suggest the nuclei of the internal cone to be under neurotrophic control of the sensory neuron that might be realized via axoplasmic transport of substances.
D000818:Animals; D001370:Axonal Transport; D002415:Cats; D003078:Colchicine / Q000494:pharmacology*; D008465:Mechanoreceptors / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009410:Nerve Degeneration; D010141:Pacinian Corpuscles / Q000648:ultrastructure*; D010525:Peripheral Nerves / Q000187:drug effects*
D003078:Colchicine
Degeneratsiia sloistykh telets (fatera--Pachini) pri applikatsii kolkhitsina na nerv.