Cellology of HLA. I. The apparent homogeneity of HLA-D.
We have demonstrated that there is a similarity in the distribution of restimulation responses of primed lymphocyte typing (PLT) cells raised between related and unrelated individuals, thus leading to the suggestion that HLA-D is a homogeneous determinant. It is proposed that within HLA a hitherto unrecognized heterogeneous structure may exist that is closely associated with HLA-D and which may give rise to intermediate reactions in primary mixed lymphocyte reactions and PLT.
D000939:Epitopes; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006801:Humans; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000276:immunology
D000939:Epitopes; D006680:HLA Antigens; D006649:Histocompatibility Antigens