[Further comment on the lipotropic action of niacin].
An investigation into the total lipids, fatty acids, total phospholipids and ATP content in the liver of rats given nicotinamide, separately and together with hydrocortisone, showed that the disclosed shifts mutually correlate well and may be explained in keeping within the bounds of the idea as to the lipotropic action of the preparations. The coincidence of the corticosteroids and nicotinamide effects in regards to mobilization of lipids and their oxidation in the liver presumes a hormonal causation of shifts on the level of lipids metabolism.
D000309:Adrenal Insufficiency / Q000378:metabolism; D000315:Adrenalectomy; D000818:Animals; D002784:Cholesterol / Q000378:metabolism; D004789:Enzyme Activation / Q000187:drug effects; D005227:Fatty Acids / Q000378:metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006854:Hydrocortisone / Q000008:administration & dosage; D050356:Lipid Metabolism; D008053:Lipid Mobilization / Q000187:drug effects; D008082:Lipotropic Agents; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D009536:Niacinamide / Q000008:administration & dosage; D009539:Nicotinic Acids / Q000494:pharmacology*; D010743:Phospholipids / Q000378:metabolism; D051381:Rats; D013997:Time Factors
D005227:Fatty Acids; D008082:Lipotropic Agents; D009539:Nicotinic Acids; D010743:Phospholipids; D009536:Niacinamide; D002784:Cholesterol; D005954:Glucosephosphate Dehydrogenase; D006854:Hydrocortisone
Eshche raz o lipotropnom deĭstvii niatsina.