Red cell ABH antigens in leukaemias and lymphomas.
The qualitative and quantitative determinations of A, B, and H antigens were studied in blood samples of 509 normal subjects and 114 patients. 11 of 53 (20.75%), 3 of 27 (11.11%), and 4 of 34 (11.76%) of adults with leukaemia, children with leukaemia and adults with lymphomas, respectively, show significantly lower antigenic scores than normal controls. Since all A, B and H antigens were found to be independently affected, the destruction of well-developed ABH antigens by a certain substance produced during the course of the disease was suspected.
D000017:ABO Blood-Group System; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D000939:Epitopes; D005260:Female; D005787:Gene Frequency; D006689:Hodgkin Disease / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000235:genetics* / Q000276:immunology; D008223:Lymphoma / Q000235:genetics* / Q000276:immunology; D008297:Male; D008875:Middle Aged
D000017:ABO Blood-Group System; D000939:Epitopes