[Human chromosome polymorphism and disordered reproductive function. II. C-variant chromosomes].
C-stained polymorphic variants of chromosomes 1, 9, 13--16, 21, 22 and Y were studied in married couples with reproductive failure (200 individuals) and in control couples having normal children and no spontaneous abortions and stillbirths. Location of heterochromatic segments, their size and heteromorphism of homologues were estimated. The individuals with reproductive failure were carriers of variants of chromosomes 9 and acrocentrics with higher content of heterochromatic material as well as with heterochromatic chromosome 9 significantly more frequently as compared with control individuals.
D000026:Abortion, Habitual / Q000235:genetics; D000328:Adult; D002900:Chromosomes, Human, 1-3 / Q000648:ultrastructure*; D002901:Chromosomes, Human, 13-15 / Q000648:ultrastructure*; D002902:Chromosomes, Human, 16-18 / Q000648:ultrastructure*; D002904:Chromosomes, Human, 21-22 and Y / Q000648:ultrastructure*; D002906:Chromosomes, Human, 6-12 and X / Q000648:ultrastructure*; D000013:Congenital Abnormalities / Q000235:genetics; D005260:Female; D005313:Fetal Death / Q000235:genetics; D014644:Genetic Variation; D006570:Heterochromatin / Q000648:ultrastructure*; D006801:Humans; D007621:Karyotyping; D008297:Male; D011110:Polymorphism, Genetic; D011247:Pregnancy; D012098:Reproduction; D012730:Sex Chromosomes / Q000648:ultrastructure*; D013194:Staining and Labeling / Q000379:methods; D014998:Y Chromosome / Q000648:ultrastructure*
D006570:Heterochromatin
Khromosomnyĭ polimorfizm i narushenie reproduktivnoĭ funktsii u cheloveka. Soobshchenie II. C-varianty khromosom.