title: Heatstroke in well-wrapped infants.
abstract: In a 3-year period in Newcastle upon Tyne a sudden illness, of which the main features were fever, shock, convulsions, hepatic disturbance, and a bleeding tendency, affected 5 infants, 4 of whom died. No aetiological agent could be demonstrated, and in the absence of a satisfactory alternative diagnosis it is suggested that a principal component of the illness was heatstroke, brought about by excessive wrapping or warming during a mild infection.
mesh_terms: D001772:Blood Cell Count; D001777:Blood Coagulation; D001833:Body Temperature Regulation; D003020:Clothing / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005334:Fever / Q000175:diagnosis; D006359:Heat Exhaustion / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006361:Heating; D006470:Hemorrhage / Q000175:diagnosis; D006801:Humans; D007223:Infant; D007239:Infections / Q000175:diagnosis; D008099:Liver / Q000503:physiopathology; D008111:Liver Function Tests; D008297:Male; D012769:Shock / Q000175:diagnosis