title: Rapid-turnover transport proteins: an index of subclinical protein-energy malnutrition.
abstract: The effect of protein and energy restriction on the plasma proteins, albumin, transferrin, prealbumin, retinol-binding protein, haptoglobulins, and immunoglobulins, was studied in obese subjects. Plasma albumin and transferrins failed to respond to short-term restriction of either protein or energy. Prealbumin and retinol-binding protein, however, were very sensitive to changes in both dietary protein and energy and responded rapidly to refeeding. Prealbumin and retinol-binding protein could be used to detect subclinical malnutrition and monitor the effectiveness of dietary treatment.
mesh_terms: D002352:Carrier Proteins / Q000378:metabolism*; D004038:Diet, Reducing; D004044:Dietary Proteins / Q000008:administration & dosage / Q000378:metabolism*; D004734:Energy Metabolism; D005260:Female; D006242:Haptoglobins / Q000032:analysis; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D009765:Obesity / Q000178:diet therapy* / Q000378:metabolism; D011228:Prealbumin / Q000032:analysis; D011502:Protein-Energy Malnutrition / Q000175:diagnosis* / Q000378:metabolism; D012177:Retinol-Binding Proteins / Q000097:blood; D054839:Retinol-Binding Proteins, Plasma; D012709:Serum Albumin / Q000032:analysis; D014168:Transferrin / Q000032:analysis
chemical_list: D002352:Carrier Proteins; D004044:Dietary Proteins; D006242:Haptoglobins; D007136:Immunoglobulins; D011228:Prealbumin; D012177:Retinol-Binding Proteins; D054839:Retinol-Binding Proteins, Plasma; D012709:Serum Albumin; D014168:Transferrin