Comparison of the adjuvant effect of three BCG preparations in mice.
Three preparations of BCG, currently in use for clinical trials in cancer, were tested for relative potency as an immunological adjuvant. Using a lymphocyte trapping assay, Pasteur Institute BCG was shown to be a more effective adjuvant than the Tice strain or the Glaxo preparation of BCG.
D000276:Adjuvants, Immunologic; D000818:Animals; D000888:Antibodies, Anti-Idiotypic / Q000096:biosynthesis; D001500:BCG Vaccine / Q000494:pharmacology*; D008198:Lymph Nodes / Q000033:anatomy & histology; D008214:Lymphocytes / Q000166:cytology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009929:Organ Size; D013154:Spleen / Q000033:anatomy & histology; D005719:gamma-Globulins / Q000008:administration & dosage
D000276:Adjuvants, Immunologic; D000888:Antibodies, Anti-Idiotypic; D001500:BCG Vaccine; D005719:gamma-Globulins