title: [The role of mepartricin in the medical treatment of benign prostatic adenoma].
abstract: A "cross over" study was carried out in a group of 22 subjects with prostatic hypertrophy in different stages, first treated with chloroformic extract of Pygeum Africanum (4 capsules/die for 30 days) and afterwards, when the symptoms reappeared, with mepartricin (3 gastroresistant tablets of 50,000 U. each/die for 30 days). Both substances proved to be active against the urinary symptomatology; however the polyene induced a significant decrease in the prostate size (evaluated by cystography), justifying the 77% of "excellent" results against the 13% obtained with the reference drug.
mesh_terms: D000368:Aged; D004341:Drug Evaluation; D006801:Humans; D008297:Male; D008613:Mepartricin / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D011090:Polyenes / Q000627:therapeutic use*; D011470:Prostatic Hyperplasia / Q000188:drug therapy*
chemical_list: D011090:Polyenes; D008613:Mepartricin
vernacular_title: Ruolo della mepartricina nella terapia medica dell'adenoma prostatico benigno.