Frequent elevation of tissue polypeptide antigen in the sera of workers exposed to bladder carcinogens.
A group of 108 male workers previously exposed to bladder carcinogens and a group of 26 patients with carcinoma of the bladder differed significantly from a control group comprising 63 healthy male donors with respect to their levels of tissue polypeptide antigen (TPA). The risk group exhibited 4-6 times more frequent elevations of TPA than did the group of healthy donors.
D015081:2-Naphthylamine / Q000009:adverse effects*; D000328:Adult; D000368:Aged; D000941:Antigens / Q000032:analysis; D001560:Benzidines / Q000009:adverse effects*; D002273:Carcinogens; D004781:Environmental Exposure; D000939:Epitopes; D005260:Female; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D008297:Male; D008875:Middle Aged; D009281:Naphthalenes / Q000009:adverse effects*; D009784:Occupational Diseases / Q000139:chemically induced* / Q000276:immunology; D010455:Peptides / Q000032:analysis; D011379:Prognosis; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced / Q000276:immunology*
D000941:Antigens; D001560:Benzidines; D002273:Carcinogens; D000939:Epitopes; D009281:Naphthalenes; D010455:Peptides; D015081:2-Naphthylamine