title: Nerve conduction velocity and refractory period as parameters of neurotoxicity.
abstract: The maximum conduction velocity (MCV) and minimum refractory period (MRP) were measured in rat sacral ventral and dorsal roots, and saphenous nerves. At 32 degrees C values for MCV were 81.45, 73.96 and 49.12 m/sec for the ventral and dorsal roots, and saphenous nerves respectively, with corresponding temperature coefficients of 3.9, 3.25 and 2.14 m/sec/degrees C. Values of MRP at 32 degrees C for the 3 nerve preparations were 0.63, 0.52 and 0.47 msec, with an average temperature coefficient of 0.04 msec/degrees C at 32 degrees C.
mesh_terms: D000818:Animals; D004558:Electric Stimulation; D006614:Hindlimb / Q000294:innervation; D008297:Male; D009431:Neural Conduction; D051381:Rats; D012032:Refractory Period, Electrophysiological; D013126:Spinal Nerve Roots / Q000502:physiology*; D013696:Temperature