title: [Role of alpha 1-antitrypsin and alpha-2 macroglobulin in hepatopathies].
abstract: Two pictures of alpha 1-antitrypsin deficiency, one associated with alpha 2-macroglobulin deficiency and one isolated case of the latter deficiency have been observed in three patients suffering from cirrhosis of the liver and/or hepatoma. On the basis of these cases, the literature on the subject is reviewed. The unusually high incidence of such anti-enzymatic deficiencies (three cases in the first eleven patients studied) in severe liver pathology, calls for a reassessment of such research and suggests that these tests should be carried out on a routine basis in cases of cryptogenetic cirrhosis and probably for long-term prognosis in cases of viral hepatitis.
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000097:blood*; D006525:Hepatitis, Viral, Human / Q000097:blood; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood*; D008113:Liver Neoplasms / Q000097:blood*; D008297:Male; D008875:Middle Aged; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000511:alpha-Macroglobulins / Q000032:analysis
chemical_list: D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins
vernacular_title: Ruolo dell'alpa 1-antitripsina e dell'alfa 2-macroglobulina nelle epatopatie.