Primary sideroblastic anemia masked by bleeding.
A patient with characteristic features of iron deficiency was unexpectedly found to have circulating siderocytes. Bone marrow iron stain at this time showed absence of both hemosiderin and ringed sideroblasts; electron microscopy revealed absence of mitochondrial iron loading but presence of cytoplasmic ferritin in normoblasts. Replenishment of iron stores led to development of typical sideroblastic anemia. These observations suggest that increased percentage of siderocytes in otherwise typical iron deficiency anemia may signify the presence of a sideroblastic process masked by iron deficiency due to bleeding.
D000368:Aged; D000747:Anemia, Hypochromic / Q000209:etiology; D000756:Anemia, Sideroblastic / Q000175:diagnosis*; D003951:Diagnostic Errors; D006471:Gastrointestinal Hemorrhage / Q000150:complications*; D006801:Humans; D008297:Male