Urinary excretion of beta2-microglobulin and other proteins in workers exposed to cadmium, lead or mercury.
For the range of exposure to heavy metals sustained by the different groups of workers, a significant increase in the urinary excretion of low and/or high molecular weight proteins was found in the workers exposed to cadmium or to lead + cadmium, but no in those exposed to lead only and those exposed to mercury. Our observations suggest that the classical "tubular" proteinuria induced by cadmium has two not necessarily concomitant components : a "tubular type" component with increased excretion of low molecular weight proteins and a "glomerular type" component with increased excretion of high molecular weight proteins.
D001609:Beta-Globulins / Q000652:urine*; D002105:Cadmium Poisoning / Q000652:urine*; D006801:Humans; D007855:Lead Poisoning / Q000652:urine*; D008630:Mercury Poisoning / Q000652:urine*; D008970:Molecular Weight; D009784:Occupational Diseases / Q000652:urine*; D011506:Proteins / Q000378:metabolism; D011507:Proteinuria / Q000139:chemically induced; D001613:beta 2-Microglobulin / Q000378:metabolism / Q000652:urine*
D001609:Beta-Globulins; D011506:Proteins; D001613:beta 2-Microglobulin