Undifferentiated carcinoma in young men: the atypical teratoma syndrome.
In 5 young men with apparent undifferentiated carcinoma involving lung, mediastinum, and lymph-nodes subsequent response to treatment, tumour-marker analysis, and histology review suggested a diagnosis of embryonal-cell carcinoma. It is suggested that atypical presentation of extragonadal germ-cell tumours may be common. Because such tumours respond to chemotherapy, accurate diagnosis is essential.
D000293:Adolescent; D000328:Adult; D018288:Carcinoma, Small Cell / Q000175:diagnosis; D002822:Choriocarcinoma / Q000175:diagnosis; D003937:Diagnosis, Differential; D004407:Dysgerminoma / Q000175:diagnosis; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D008223:Lymphoma / Q000175:diagnosis; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis*; D009362:Neoplasm Metastasis; D013724:Teratoma / Q000175:diagnosis*; D013736:Testicular Neoplasms / Q000175:diagnosis