An alkaline protease in the delayed hypersensitivity skin lesions in the guinea-pigs.
An alkaline hemoglobinolytic protease was extracted from the delayed hypersensitivity skin lesions induced by bovine gamma-globulin as an antigen in the guinea-pig. The enzyme was heat-labile and inhibited by thiol-blocking reagents. The mol.wt. was more than 100,000 and optimal pH around 9.
D000818:Animals; D006168:Guinea Pigs; D006863:Hydrogen-Ion Concentration; D006968:Hypersensitivity, Delayed / Q000201:enzymology*; D007700:Kinetics; D010447:Peptide Hydrolases / Q000302:isolation & purification / Q000378:metabolism*; D012867:Skin / Q000201:enzymology*; D005719:gamma-Globulins
D005719:gamma-Globulins; D010447:Peptide Hydrolases