title: Electrical bone-growth stimulation in an experimental model of delayed union.
abstract: An experimental model has been devised for the consistent production of delayed bone healing of the tibia in adult dogs. A double-blind trial, with bias eliminated, was used to evaluate the use of a commercially available direct-current bone-growth stimulator with this model. The stimulator produced a statistically significant acceleration of bone healing at four weeks in the experimental model. Osteogenesis was normal, and no dysplastic, inflammatory, or neoplastic changes were found. This research has shown that electrical stimulation of bone is safe and augments bone formation. The bone-growth stimulator unit remains on trial, but in future it may alter the management of many difficult orthopaedic problems.
mesh_terms: D000818:Animals; D004285:Dogs; D004558:Electric Stimulation / Q000295:instrumentation*; D004599:Electric Stimulation Therapy; D005599:Fractures, Ununited / Q000628:therapy*; D006801:Humans; D010012:Osteogenesis; D013977:Tibia / Q000254:growth & development; D013978:Tibial Fractures / Q000628:therapy; D014945:Wound Healing