Formylation and acetylation of 4-chloroaniline by a Streptomyces sp.
4-Chloroaniline was metabolized in a liquid growth medium by a Streptomyces sp. which was isolated from soil. After 60 gours of incubation the aniline had disappeared and several metabolites could be detected by thin layer chromatographic analysis. 4-Chloroformylaniline and 4-chloroacetanilide were identified as products. The formation of a formylanilide by the actinomycete indicates a new mechanism of microbial aniline transformation.
D000107:Acetylation; D000813:Anilides / Q000378:metabolism; D000814:Aniline Compounds / Q000378:metabolism*; D012988:Soil Microbiology; D013302:Streptomyces / Q000378:metabolism*
D000813:Anilides; D000814:Aniline Compounds