Vagotomy for treatment of severe obesity.
Three women weighing 137, 133, and 135 kg underwent truncal vagotomy; after 16, 20, and 24 weeks they had lost 10, 17, and 19 kg respectively without serious side-effects. No dietary restrictions have been imposed, but they are eating less than they were preoperatively and report a total lack of hunger. Truncal vagotomy may be a useful treatment for severe obesity.
D000328:Adult; D001069:Appetite Regulation; D001835:Body Weight; D002149:Energy Intake; D005260:Female; D005500:Follow-Up Studies; D005518:Food Preferences; D006801:Humans; D009765:Obesity / Q000628:therapy*; D014628:Vagotomy