On the presence of lysozyme in the Nuclei of Leukocytes.
The purified chromatin of leukocyte nuclei from two patients, one with chronic granulocytic and another with acute myelomonocytic leukemia, has been investigated for lysozyme activity. The chromatin contained 4.8% resp. 4% of the total amount of lysozyme found in the leukocytes. The function of lysozyme in the nucleus remains unclear.
D001798:Blood Proteins / Q000032:analysis; D002467:Cell Nucleus / Q000201:enzymology*; D002843:Chromatin / Q000032:analysis; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000473:pathology; D007951:Leukemia, Myeloid / Q000473:pathology; D015470:Leukemia, Myeloid, Acute / Q000473:pathology; D007962:Leukocytes / Q000201:enzymology*; D009113:Muramidase / Q000378:metabolism*
D001798:Blood Proteins; D002843:Chromatin; D009113:Muramidase