Platelet-monoamine-oxidase activity predicts response to lithium in manic-depressive illness.
Platelet-monoamine-oxidase activity predicts treatment response to lithium in manic-depressive illness. In the treatment-responsive group enzyme activity is similar to that in normal controls, whereas in the treatment-refractory group enzyme activity is significantly less than both control and treatment-responsive groups.
D000208:Acute Disease; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000201:enzymology; D001792:Blood Platelets / Q000201:enzymology*; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D008995:Monoamine Oxidase / Q000097:blood* / Q000172:deficiency; D011379:Prognosis
D008094:Lithium; D008995:Monoamine Oxidase