Antithrombin-III transfusion in disseminated intravascular coagulation.
Three patients with a severe bleeding disorder and disseminated intravascular coagulation were effectively treated with human antithrombin-III concentrates. This treatment, followed by administration of prothrombin complex and platelet suspensions, resulted in a normal haemostasis, which was maintained during clinical investigations and surgery.
D000328:Adult; D000368:Aged; D000991:Antithrombins / Q000008:administration & dosage*; D001792:Blood Platelets; D001803:Blood Transfusion; D003450:Cryoglobulins / Q000008:administration & dosage; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006487:Hemostasis; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D066298:In Vitro Techniques; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000628:therapy; D011516:Prothrombin / Q000008:administration & dosage
D000991:Antithrombins; D003450:Cryoglobulins; D011516:Prothrombin; D006493:Heparin