title: [Effect of the gamma-isomer of HCCH on the functional state of the sex glands of rats].
abstract: The effect of the HCCH gamma-isomer on the function of sexual glands in rats was studied. Administration of the HCCH gamma-isomer in a dose of 5mg/kg body weight was found to bring down the pregnancy index in the group where test females were mated with test males. This indicator, as well as the mating index were down in the group where control males were mated with test females. Moreover, the offspring of animals, where test females were mated with test males and also in the group of control males and test females sacrificed before and during gestation a significant lagging of the weight gain at the end of the nursing period was recorded. Animals receiving the HCCH gamma-isomer in a dose of 0.05 mg/kg body weight did not differ from the control rats in all of the indicators under study.
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D004971:Estrus / Q000187:drug effects; D005260:Female; D006066:Gonads / Q000187:drug effects*; D006128:Growth / Q000187:drug effects; D001556:Hexachlorocyclohexane / Q000494:pharmacology*; D008297:Male; D011247:Pregnancy; D051381:Rats; D012098:Reproduction / Q000187:drug effects; D013081:Sperm Motility / Q000187:drug effects; D013997:Time Factors
chemical_list: D001556:Hexachlorocyclohexane
vernacular_title: K voprosu o vliianii gamma-izomera GKhTsG na funktsional'noe sostoianie polovykh zhelez krys