[Group and strain-specific determinants of the influenza virus nucleoprotein].
An antiserum to a purified nucleoprotein preparation of influenza virus recombinant A/MRC/11 obtained from A/Port Chalmers/1/73 and A/PR/8/34 strains, was examined for the presence of antibody before and after its adsorption with sodium sarcolysil sulphate-disrupted influenza. A viruses by the methods of radial and double immunodiffusion. The antiserum was found to contain both group- and strain-specific (for MRC-11 nucleoprotein) antibodies. In radial immunodiffusion tests MRC-11 nucleoprotein showed the greatest affinity to A/PR/8/34 nucleoprotein and differed from A/Scotland/860/74 and A/USSR/090/77.
D000327:Adsorption; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D002642:Chick Embryo; D000939:Epitopes; D007114:Immunization; D005779:Immunodiffusion / Q000379:methods; D009980:Influenza A virus / Q000276:immunology*; D009698:Nucleoproteins / Q000276:immunology*; D051381:Rats; D014764:Viral Proteins / Q000276:immunology*; D014776:Virus Cultivation
D000956:Antigens, Viral; D000939:Epitopes; D009698:Nucleoproteins; D014764:Viral Proteins
Gruppovye i shatmmospetsificheskie determinanty nukleoproteida virusa grippa.