[Intensive albumin therapy and pressure modifications during acute coronary ischemia in the dog].
The influence, on left ventricular pressure, of an intensive human albumin administration, has been studied in eight open chest dogs, during a second myocardial ischemia produced by coronary occlusion. After elevation of plasmatic proteins, the systolic and telediastolic left ventricular pressure, the dP/dt and the cardiac rate are measured. Any hypotensive effect was not observed in the human albumin-perfused dogs, nor in another control groups of six animals.
D000818:Animals; D001157:Arterial Occlusive Diseases; D001794:Blood Pressure / Q000187:drug effects; D001798:Blood Proteins / Q000378:metabolism; D003327:Coronary Disease / Q000188:drug therapy*; D003331:Coronary Vessels; D004285:Dogs; D004562:Electrocardiography; D006339:Heart Rate / Q000187:drug effects; D006352:Heart Ventricles; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D012709:Serum Albumin / Q000627:therapeutic use*
D001798:Blood Proteins; D012709:Serum Albumin
L'albuminothérapie intensive et les modifications tensionnelles au cours d'une ischemie coronaire alguè chez le chien