[Modification of the thrombocyte function using hormonal contraception. 2. Platelet adhesiveness, thromboelastography, conclusions].
Platelet adhesiviness and thrombelastographic investigations in plasma by 102 women treated with Ovosiston, an anticonceptive agent were observed. A significant increase of adhesiveness and thrombelastographic variations was found. In conclusion showed abnormalities of platelet functions and thrombelastographic values point to influences by oral contraceptive agent Ovosiston. In combination with other favouring factors the risk of thromboembolism must be enhanced.
D001777:Blood Coagulation / Q000187:drug effects; D002715:Chlormadinone Acetate / Q000494:pharmacology; D003276:Contraceptives, Oral / Q000494:pharmacology*; D003278:Contraceptives, Oral, Hormonal / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008656:Mestranol / Q000494:pharmacology; D010973:Platelet Adhesiveness / Q000187:drug effects*; D010974:Platelet Aggregation / Q000187:drug effects; D013916:Thrombelastography
D003276:Contraceptives, Oral; D003278:Contraceptives, Oral, Hormonal; D002715:Chlormadinone Acetate; D008656:Mestranol
Beeinflussung der Thrombozytenfunktion durch hormonelle Kontrazeption