Demonstration of a chorionic gonadotropin-like substance in rabbit morulae.
Rabbit morulae were treated with specific indirect immunofluorescence and immunoperoxidase histochemical techniques. The first antibody in both systems was rabbit anti-human chorionic gonadotropin (hCG) beta-subunit. Negative controls revealed a complete absence of reaction. All morulae incubated with the double-antibody system showed a positive reaction. Rabbit morulae thus present a substance with antigenic determinants similar to the beta-subunit of hCG. The physiologic role of this substance is unknown.
D000818:Animals; D001755:Blastocyst / Q000032:analysis*; D001756:Blastoderm / Q000032:analysis* / Q000276:immunology; D006063:Chorionic Gonadotropin / Q000032:analysis* / Q000276:immunology; D000939:Epitopes; D005455:Fluorescent Antibody Technique; D007124:Immunoenzyme Techniques; D011817:Rabbits / Q000196:embryology*
D006063:Chorionic Gonadotropin; D000939:Epitopes