[Distribution study using 57Co-, 51Cr-, 111In- and 99mTc-bleomycin in mice with a solid Ehrlich carcinoma].
From the comparative studies of 57Co-, 51Cr-, 111In- and 99mTc-Bleomycin using 282 solid Ehrlich-carcinoma-bearing mice, 57Co was found to be the most suitable bleomycin preparation for tumorscintigraphy. The results obtained by 111In-Bleomycin of linear tumor cell absorption indicates a possible use of 111In-Bleomycin as an agent for objective histological differentiation also in cells previously treated with therapeutic agents.
D000818:Animals; D001761:Bleomycin / Q000378:metabolism; D002286:Carcinoma, Ehrlich Tumor / Q000175:diagnosis*; D002860:Chromium Radioisotopes; D003037:Cobalt Radioisotopes; D005260:Female; D007204:Indium; D051379:Mice; D009369:Neoplasms / Q000175:diagnosis; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013667:Technetium
D002860:Chromium Radioisotopes; D003037:Cobalt Radioisotopes; D011868:Radioisotopes; D007204:Indium; D001761:Bleomycin; D013667:Technetium
Verteilungsstudie mit 57Co-, 51Cr-, 111In- und 99mTc- Bleomycin in Mäusen mit einem soliden Ehrlich-Karzinom