title: Studies on the cytochemical localization of adenylate-cyclase activity in Dugesia lugubris s.I.
abstract: The localization of adenylate-cyclase activity in Dugesia lugubris s.1. has been investigated cytochemically using 5'-adenylyl-imidodiphosphate as substrate. The enzyme was localized in mucous gland cells, in rhabdite cells, in intercellular spaces and also in nerve endings of this planarian. The presence of adenylate-cyclase on the membrane suggests that it might mediate different stimulus-secretion coupling by increasing cyclic AMP synthesis in specialized areas of the planarian.
mesh_terms: D000262:Adenylyl Cyclases / Q000032:analysis*; D000818:Animals; D006651:Histocytochemistry; D010932:Planarians / Q000201:enzymology* / Q000648:ultrastructure; D013194:Staining and Labeling; D014419:Turbellaria / Q000201:enzymology*
chemical_list: D000262:Adenylyl Cyclases