title: Erythrocyte ghosts (Na+ + K+) ATPase activity in Duchenne's dystrophy and myotonia.
abstract: In Duchenne muscular dystrophy the activity of (Na+ + K+)ATPase in erythrocyte ghosts is reduced and its reaction to ouabain is paradoxical both in low sodium and high sodium systems. No such changes were seen in a case of Becker dystrophy, in limb-girdle dystrophy, and in neurogenic atrophy of muscles. In myotonic dystrophy and congenital myotonia the activity of ATPase and its inhibition by ouabain were depressed.
mesh_terms: D000251:Adenosine Triphosphatases / Q000097:blood*; D001693:Biological Transport, Active; D004910:Erythrocyte Membrane / Q000201:enzymology*; D004912:Erythrocytes / Q000201:enzymology*; D006801:Humans; D009136:Muscular Dystrophies / Q000201:enzymology*; D009222:Myotonia / Q000201:enzymology*; D010042:Ouabain / Q000494:pharmacology; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood
chemical_list: D010042:Ouabain; D012964:Sodium; D000251:Adenosine Triphosphatases; D011188:Potassium