A study of Sézary cells in peripheral blood and skin lesions.
A patient with Sézary syndrome is presented. By phase contrast and scanning electron microscopy Sézary cells were demonstrated in peripheral blood and in skin tissue. Investigation of atypical mononuclear cells seen in the peripheral blood showed that these cells lack receptors for sheep erythrocytes. C3 and Fcgamma. Similarly, an examination of dermal mononuclear cell infiltrates showed that most of the cells lack receptors for sheep erythrocytes, C3 and Fcgamma.
D000368:Aged; D003176:Complement C3; D006801:Humans; D007141:Immunoglobulin Fc Fragments; D008214:Lymphocytes / Q000648:ultrastructure*; D008297:Male; D012751:Sezary Syndrome / Q000276:immunology / Q000473:pathology*; D012867:Skin / Q000473:pathology* / Q000648:ultrastructure
D003176:Complement C3; D007141:Immunoglobulin Fc Fragments