[2 variants of the anti-arrhythmic effect of atropine in extrasystole].
The antiarrhythmic effect of a single intravenous atropine injection (0.02 mg/kg body mass) was studied in 202 patients with extrasystole of various origin by rhythmography. Record of the chronotropic reaction and dynamics of the extrasystole interval suggests that there are two variations of the antiarrhythmic effect of atropine: frequency suppression of extrasystole and a "pure" antiarrhythmic effect. The data obtained are evidence that the mechanism of the antiarrhythmic effect of atropine is heterogeneous and complex.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001285:Atropine / Q000627:therapeutic use*; D001919:Bradycardia / Q000139:chemically induced; D005117:Cardiac Complexes, Premature / Q000188:drug therapy*; D003864:Depression, Chemical; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008875:Middle Aged; D013268:Stimulation, Chemical; D013610:Tachycardia / Q000139:chemically induced
D001285:Atropine
2 varianta protivoaritmicheskogo deĭstviia atropina u bol'nykh s ékstrasistolieĭ.