Inosiplex for localized herpes zoster in childhood cancer patients: preliminary controlled study.
By multiple criteria, inosiplex-a reputed stimulator of virus-sensitized lymphocytes-had no demonstrable therapeutic effects in a preliminary controlled study of patients with localized herpes zoster and cancer. Lymphocytes from the six drug-treated patients were no more responsive to varicella-zoster antigen and phytohemagglutinin than were lymphocytes from seven patients who received a placebo.
D002648:Child; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006562:Herpes Zoster / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007288:Inosine / Q000031:analogs & derivatives*; D007542:Inosine Pranobex / Q000494:pharmacology / Q000627:therapeutic use*; D009369:Neoplasms / Q000150:complications; D010919:Placebos
D010919:Placebos; D007288:Inosine; D007542:Inosine Pranobex