Metabolism of benzo(a)pyrene-3,6-quinone and 3-hydroxybenzo(a)pyrene in liver microsomes from 3-methylcholanthrene-treated rats. A possible role of DT-diaphorase in the formation of glucuronyl conjugates.
D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism*; D001728:Dicumarol / Q000494:pharmacology; D005965:Glucuronates / Q000096:biosynthesis; D007700:Kinetics; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism*; D011808:Quinone Reductases / Q000378:metabolism*; D011809:Quinones / Q000378:metabolism; D051381:Rats
D001580:Benzopyrenes; D005965:Glucuronates; D011809:Quinones; D008748:Methylcholanthrene; C021338:3-hydroxybenzo(a)pyrene; D001728:Dicumarol; C018003:benzo(a)pyrene-3,6-quinone; D009247:NADH, NADPH Oxidoreductases; D011808:Quinone Reductases