Receptor proteins for androgens in prostatic disease.
The suitability of an exchange assay with methyltrienolone (R1881) for the measurement of androgen receptors in human prostatic tumours has been investigated. Having established the specificity of this compound for androgen receptor assay, a pilot study was carried out to measure dihydrotestosterone (DHT) receptor in 27 cases of benign hypertrophy and 18 cases of malignant tumour of the prostate.
D013196:Dihydrotestosterone / Q000378:metabolism; D004963:Estrenes / Q000378:metabolism* / Q000494:pharmacology; D006854:Hydrocortisone / Q000378:metabolism; D008297:Male; D011374:Progesterone / Q000378:metabolism; D011470:Prostatic Hyperplasia / Q000378:metabolism*; D011471:Prostatic Neoplasms / Q000378:metabolism*; D011944:Receptors, Androgen / Q000187:drug effects / Q000378:metabolism*; D011987:Receptors, Steroid / Q000378:metabolism*; D045165:Testosterone Congeners / Q000378:metabolism* / Q000494:pharmacology
D004963:Estrenes; D011944:Receptors, Androgen; D011987:Receptors, Steroid; D045165:Testosterone Congeners; D013196:Dihydrotestosterone; D011374:Progesterone; D006854:Hydrocortisone