[Adverse effects of drugs: syncope due to prenylamine (author's transl)].
The authors report on 4 Intensive Care Unit cases, hospitalized for syncopes due to serious ventricular arrhythmias. They all presented long Q-T and were receiving treatment with prenylamine. Improvements were observed on suspension of the drug, suggesting therefore that during this treatment, frequent electrocardiographic checks, especially for elderly patients, should be carried out. Caution should also be exercised in associations with other chinidinosimiles and hypokaliemic drugs
D000368:Aged; D001145:Arrhythmias, Cardiac / Q000139:chemically induced*; D002037:Bundle-Branch Block / Q000139:chemically induced; D005117:Cardiac Complexes, Premature / Q000139:chemically induced; D005260:Female; D006801:Humans; D008297:Male; D011299:Prenylamine / Q000009:adverse effects* / Q000627:therapeutic use; D013575:Syncope / Q000139:chemically induced*
D011299:Prenylamine
Effetti sfavorevoli dei farmaci: sincope da prenilamina