title: [Treatment of agammaglobulinemia in the adult; report of 9 cases].
abstract: The study of 9 cases of agammaglobulinemia in the adult shows the classical symptomatology of these diseases. The evolutive study deals with too small a series to demonstrate statistically the superiority of the substitutive treatment over a simple chemo-therapeutic prevention of the infection, but nevertheless it shows : 1) that prognosis is bad only in cases of gross anatomical and physiological alterations and when they are the sole responsible for a fatal evolution; 2) that the substitutive treatment is only really efficient when given at high doses; the minimum dose of 250 mg per day seems advisable.
mesh_terms: D000293:Adolescent; D000328:Adult; D000361:Agammaglobulinemia / Q000188:drug therapy*; D000906:Antibodies / Q000627:therapeutic use; D004306:Dose-Response Relationship, Immunologic; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D008171:Lung Diseases / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D005719:gamma-Globulins / Q000008:administration & dosage*
chemical_list: D000906:Antibodies; D005719:gamma-Globulins
vernacular_title: Agammaglobulinémies de l'adulte évolution sous traitement (à propos de 9 observations).