title: ["Revertase" project: results of carrying out the scientific program].
abstract: The article summarizes the data obtained within the scope of the "Revertase" project organized in 1972 under the guidance of Scientific Councel on Molecular Biology. The scientific program included four main topics: synthesis of complementary DNA via reverse transcription on the various RNA templates and their use as tools in molecular biology, enzymatic synthesis of structural genes in double DNA-polymerase system and their propagation by means of genetic engineering, enzymology of reverse transcription, problems of molecular oncornavirology. It is stressed that the success in realization of this wide and intensive research program was achieved due to cooperative efforts and division of labour between scientists of different specialities due to international cooperation within the frame of the project. Appearance of more than 80 publications between 1973 and 1977 clearly manifested that the program was fullfilled and led to creation of a new area of research absent in the given countries before functioning of the "Revertase" project.
mesh_terms: D000818:Animals; D009189:Avian Myeloblastosis Virus / Q000201:enzymology; D001483:Base Sequence; D002417:Cattle; D002472:Cell Transformation, Viral; D004247:DNA / Q000096:biosynthesis; D011088:DNA Ligases; D004256:DNA Polymerase I; D004262:DNA Restriction Enzymes; D005796:Genes; D005814:Genes, Viral; D005818:Genetic Engineering; D005914:Globins / Q000235:genetics; D001909:Leukemia Virus, Bovine / Q000201:enzymology; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger / Q000378:metabolism; D012194:RNA-Directed DNA Polymerase; D012106:Research; D012190:Retroviridae / Q000235:genetics*; D014586:USSR; D014790:Visna-maedi virus / Q000201:enzymology
chemical_list: D012333:RNA, Messenger; D005914:Globins; D004247:DNA; D012194:RNA-Directed DNA Polymerase; D004256:DNA Polymerase I; D004262:DNA Restriction Enzymes; D011088:DNA Ligases
vernacular_title: Proekt "revertaza": itogi vypolneniia nauchnoĭ programmy.