Absence of a serologically detectable association of murine beta2-microglobulin with the embryonic F9 antigen.
The association of murine beta2-microglobulin to the early embryonic F9 antigen has been investigated by indirect immunofluorescence and by radioimmunoassay. Although some cell lines carry both types of molecules, the beta2-microglobulin was not found expressed on primitive teratocarcinoma cells, where F9 antigen was primarily detected. It is concluded that the low m.w. (12,000 daltons) subunit that was reported to be associated to the F9 antigen is not the adult beta2-microglobulin.
D000818:Animals; D000951:Antigens, Neoplasm / Q000032:analysis*; D001609:Beta-Globulins / Q000276:immunology*; D002460:Cell Line; D004622:Embryo, Mammalian / Q000276:immunology*; D005260:Female; D005455:Fluorescent Antibody Technique; D006649:Histocompatibility Antigens / Q000032:analysis; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D051379:Mice; D008806:Mice, Inbred AKR; D008809:Mice, Inbred C3H; D011247:Pregnancy; D011817:Rabbits; D011863:Radioimmunoassay; D013724:Teratoma / Q000276:immunology; D001613:beta 2-Microglobulin / Q000276:immunology*
D000951:Antigens, Neoplasm; D001609:Beta-Globulins; D006649:Histocompatibility Antigens; D001613:beta 2-Microglobulin