Cholestasis in acute alcoholic liver disease.
10 of a series of 108 patients with alcoholic liver disease presented with cholestasis associated with non-cirrhotic alcoholic liver disease and without evidence of extrahepatic biliary obstruction. In 7 patients liver histology and the associated conditions presenting as cholestasis were heterogeneous. However, in 3 patients who had been drinking excessively before cholestatic jaundice developed, cholestasis was a major feature of liver histology. The term acute alcoholic cholestasis is suggested for this apparently distinct syndrome of cholestatic jaundice in the absence of hepatitis.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications* / Q000473:pathology; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications* / Q000473:pathology; D002779:Cholestasis / Q000209:etiology* / Q000473:pathology; D005234:Fatty Liver / Q000139:chemically induced / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications* / Q000473:pathology; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged