Electrophoretic pattern of serum proteins in leprosy.
Sera collected from 65 patients having various types of leprosy and 20 healthy human beings were studied for the determination of total serum proteins, paper electrophoresis for protein types and albumin globulin ratios. Significant changes in protein equilibrium with the presence of hypoalbuminemia and increases in various globulin fractions (except beta globulin) were observed in patients having lepromatous and dimorphous leprosy. An abnormal protein band was also detected in 3 of 20 cases of lepromatous leprosy. The patients suffering from tuberculoid and polyneuritic leprosy did not show much protein disequilibrium except for mild rises in serum alpha-2 and reductions in serum beta globulins.
D000510:Alpha-Globulins / Q000032:analysis; D001609:Beta-Globulins / Q000032:analysis; D001797:Blood Protein Electrophoresis; D001798:Blood Proteins / Q000032:analysis*; D005260:Female; D006801:Humans; D007918:Leprosy / Q000097:blood* / Q000473:pathology; D008297:Male; D012709:Serum Albumin / Q000032:analysis; D012712:Serum Globulins / Q000032:analysis; D005719:gamma-Globulins / Q000032:analysis
D000510:Alpha-Globulins; D001609:Beta-Globulins; D001798:Blood Proteins; D012709:Serum Albumin; D012712:Serum Globulins; D005719:gamma-Globulins