Mustard operation and creation of ventricular septal defect in two patients with transposition of the great arteries, intact ventricular septum and pulmonary vascular disease.
The condition of patients with transposition of the great arteries, intact ventricular septum and severe pulmonary vascular disease is inoperable with present techniques. In a series of 260 surgically treated patients with transposition of the great arteries and intact ventricular spetum, 5 had severely increased pulmonary vascular resistance, and all 5 died; postmortem examination confirmed the presence of severe pulmonary vascular disease. The concept of the "palliative Mustard" procedure was applied in two children with transposition of the great arteries, intact ventricular spetum and pulmonary vascular disease who underwent the Mustard operation with creation of a ventricular septal defect. The postoperative course was uneventful in both patients. Thirteen and 5 months, respectively, after operation, both are physically active and have respective arterial oxygen saturation levels of 94 and 92 percent.
D000783:Aneurysm / Q000000981:diagnostic imaging; D000790:Angiocardiography; D001784:Blood Gas Analysis; D006328:Cardiac Catheterization; D002675:Child, Preschool; D005260:Female; D006346:Heart Septum / Q000601:surgery*; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008722:Methods; D010166:Palliative Care; D011651:Pulmonary Artery / Q000000981:diagnostic imaging; D011660:Pulmonary Heart Disease / Q000000981:diagnostic imaging / Q000601:surgery*; D014188:Transposition of Great Vessels / Q000000981:diagnostic imaging / Q000601:surgery*