[Comparison of the cytomorphological classification with the cytochemical differentiation of acute lymphatic leukemia in children].
In 100 children with acute lymphatic leukaemia the cytomorphological subclassification of the pathological cell type was made according to Mathé and the French-American-British Co-operative group (FAB). In addition, all cases of leukaemia were differentiated according to their cytochemical type. Lymphoblasts from 10 cases of leukaemia could be subclassified immunologically. From 71 children will ALL the survival rates of those cases of leukaemia subclassified cytomorphologically and the cytochemical reactions were compiled and partially compared. Microlymphoblastic leukaemia could be found to be the most frequent type of ALL at children's age. Prolymphocytic leukaemias were characterized by a favourable survival rate and the highest percentage of ALL with the PAS type. Macrolymphoblastic and microlymphoblastic cases of leukaemia revealed no essential differences of survival rate, but significant differences of cytochemical reactions.
D002648:Child; D006651:Histocytochemistry; D006801:Humans; D007945:Leukemia, Lymphoid / Q000097:blood / Q000145:classification*; D008214:Lymphocytes / Q000145:classification / Q000166:cytology*; D011379:Prognosis; D012397:Rosette Formation
Vergleich der zytomorphologischen Klassifizierung mit der zytochemischen Differenzierung der akuten lymphatischen Leukämie bei Kindern.