title: Analysis of prostatic fluid in prostatic disease.
abstract: The current studies of expressed prostatic fluid tend to confirm our previous reported pilot observations of a shift in lactic dehydrogenase (LDH) isoenzymes to a predominance of LDHV in patients with prostatic malignancy. They also suggest a decrease in concentration of acid phosphatase and an increase in concentration of protein in the presence of carcinoma of the prostate. These observations suggest a diffuse metabolic alteration of the prostate in the presence of prostatic carcinoma.
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism; D000328:Adult; D000368:Aged; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000201:enzymology* / Q000378:metabolism; D011469:Prostatic Diseases / Q000201:enzymology*; D011470:Prostatic Hyperplasia / Q000201:enzymology / Q000378:metabolism; D011471:Prostatic Neoplasms / Q000201:enzymology / Q000378:metabolism; D011472:Prostatitis / Q000201:enzymology / Q000378:metabolism; D011506:Proteins / Q000378:metabolism
chemical_list: D007527:Isoenzymes; D011506:Proteins; D007770:L-Lactate Dehydrogenase; D000135:Acid Phosphatase