Models for mRNA translation: theory versus experiment.
Three models for mRNA translation are discussed in the light of available experimental data. It is concluded that the elongation rates vary along a messenger, possibly as a result of a coupling between ribosome movement and mRNA secondary structure. Some promising areas of further experimentation are indicated.
D000510:Alpha-Globulins / Q000096:biosynthesis; D001435:Bacteriophages; D001609:Beta-Globulins / Q000096:biosynthesis; D006801:Humans; D008954:Models, Biological; D010441:Peptide Chain Elongation, Translational; D010442:Peptide Chain Initiation, Translational; D010443:Peptide Chain Termination, Translational; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism*; D012270:Ribosomes / Q000378:metabolism; D014764:Viral Proteins / Q000096:biosynthesis
D000510:Alpha-Globulins; D001609:Beta-Globulins; D012333:RNA, Messenger; D014764:Viral Proteins