Epidermal location of beta-2-microglobulin in human skin.
Beta-2-microglobulin (beta2-m) is associated with the epidermis in normal and pathological human skin and gives an immunofluorescence pattern similar to that of pemphigus antibodies and concanavalin A (Con-A). Inhibition experiments indicate, however, that the binding site of anti-beta2-m is not identical with that of pemphigus antibodies or Con-A. It is suggested that beta2-m might be an epidermal cell surface marker useful for the study of antigens associated with the epidermal cell surface.
D001609:Beta-Globulins / Q000378:metabolism*; D005455:Fluorescent Antibody Technique; D006801:Humans; D012867:Skin / Q000276:immunology / Q000378:metabolism*; D001613:beta 2-Microglobulin / Q000378:metabolism*
D001609:Beta-Globulins; D001613:beta 2-Microglobulin