Lymphocyte reactivity against virally transformed cells in patients with urologic cancer.
Lymphocytes from patients with urologic cancer were tested in microcytotoxicity assays against human cells transformed by cytomegalovirus. Human lymphocytes were significantly cytotoxic against the transformed cell line when compared to a normal human control cell line. Patients with prostatic carcinoma demonstrated greater target cell reduction than those with benign prostatic hyperplasia.
D000230:Adenocarcinoma / Q000276:immunology; D000956:Antigens, Viral; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002472:Cell Transformation, Viral; D003587:Cytomegalovirus; D003601:Cytotoxicity Tests, Immunologic; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D011470:Prostatic Hyperplasia / Q000276:immunology; D011471:Prostatic Neoplasms / Q000276:immunology; D014571:Urologic Neoplasms / Q000276:immunology*
D000956:Antigens, Viral