High incidence of undetected neoplasia in maldescended testes.
Testicular biopsy specimens from 4 (8%) of 50 men previously treated for maldescended testes had a carcinoma-in-situ pattern. 2 of these men had adjacent invasive carcinoma (seminoma and embryonal carcinoma). The patient with embryonal carcinoma had an enlarged testis but the 3 other patients with neoplasia had no clinical signs or symptoms of malignancy. Routine follow-up including testicular biopsy in young men with maldescended testes is essential because of the increased risk of malignancy and may detect testicular neoplasia at a stage when orchidectomy alone is curative.
D000293:Adolescent; D000328:Adult; D001284:Atrophy; D001706:Biopsy; D003456:Cryptorchidism / Q000473:pathology*; D004407:Dysgerminoma / Q000473:pathology; D006801:Humans; D008297:Male; D012306:Risk; D013724:Teratoma / Q000473:pathology; D013736:Testicular Neoplasms / Q000473:pathology*; D013737:Testis / Q000473:pathology