Increased adipose-tissue lipoprotein-lipase activity in moderately obese men after weight reduction.
Most of the many metabolic abnormalities associated with obesity are corrected by weight reduction. Adipose-tissue lipoprotein-lipase activity per cell is increased in obesity. Adipose-tissue lipoprotein-lipase was significantly higher in seven previously obese men studied at a stable reduced weight than in a control population. In fact, enzyme activity was significantly higher than would have been predicted from the obese men's maximum weight. These results indicate that abnormalities in adipose-tissue lipoprotein lipase may have a primary role in the development of obesity.
D000273:Adipose Tissue / Q000201:enzymology*; D000328:Adult; D001835:Body Weight; D002452:Cell Count; D006801:Humans; D008071:Lipoprotein Lipase / Q000378:metabolism*; D008297:Male; D009765:Obesity / Q000201:enzymology* / Q000209:etiology / Q000473:pathology
D008071:Lipoprotein Lipase