title: Wheat fibre and irritable bowel syndrome. A controlled trial.
abstract: Twenty-six patients with irritable bowel syndrome entered a controlled trial of diets with a high or low wheat-fibre content. After 6 weeks on the high-wheat fibre regimen there was significant improvement in symptoms and an objective change in colonic motor activity. No such improvement occurred on the low-fibre regimen. Patients with irritable bowel syndrome should be encouraged to increase their daily intake of wheat fibre.
mesh_terms: D000328:Adult; D002482:Cellulose / Q000008:administration & dosage* / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003106:Colon / Q000503:physiopathology; D003109:Colonic Diseases, Functional / Q000178:diet therapy* / Q000503:physiopathology; D004043:Dietary Fiber / Q000627:therapeutic use*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010528:Peristalsis; D014908:Triticum
chemical_list: D004043:Dietary Fiber; D002482:Cellulose