title: Absorption, elution and blocking studies with the complex antiserum ST.
abstract: Quantitative absorptions and elutions were performed with the broadly reactive serum ST. The major component of this serum is directed towards the B-locus antigens Bw35, B5, and B18, which comprise the 4c CREG. A second component contains lower titered antibodies which react with members of the 4c CREG, but also appear to detect qualitative and quantitative variations associated with B-locus specificities, B15, B17 and B8. Blocking studies indicate that these antibodies do not bind to the same sites on B8 cells as well-defined anti-B8 sera. These findings are discussed in terms of public specificities at the B-locus or a new specificity at a closely linked locus.
mesh_terms: D000042:Absorption; D001792:Blood Platelets / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D006801:Humans; D007106:Immune Sera; D007140:Immunoglobulin Fab Fragments / Q000276:immunology
chemical_list: D000939:Epitopes; D007106:Immune Sera; D007140:Immunoglobulin Fab Fragments