Subclinical ergotism.
The systolic blood-pressure at the ankle and the first toe was measured in 30 patients, mean age 42, who had taken ergotamine regularly for more than a year. With one exception, the patients had no symptoms or signs of arterial insufficiency in the limbs, but all had low-normal or abnormal foot systolic blood-pressures. In a group of 13 patients who stopped taking ergotamine the distal pressures rose significantly and from the ninth day were normal.
D000328:Adult; D000368:Aged; D000842:Ankle / Q000098:blood supply; D001132:Arm / Q000098:blood supply; D001795:Blood Pressure Determination; D004878:Ergotamine / Q000506:poisoning / Q000627:therapeutic use; D004881:Ergotism / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007022:Hypotension / Q000139:chemically induced / Q000175:diagnosis; D007383:Intermittent Claudication / Q000139:chemically induced / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D010992:Plethysmography, Impedance; D014034:Toes / Q000098:blood supply
D004878:Ergotamine