[Effect of cyngal on gastric secretion in rats].
The authors studied the influence of gallic salt of cynoglossophin-heliosupin alkaloid (cyngal), extracted from Cynoglossum officinale L. on the gastric secretion of rats. Cyngal proved to stimulate the secretory function of the rat stomach, beginning from the dose of 0.25 mg/kg. This action is explained by the capacity of the preparation to release histamine from the labile depot.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D005707:Gallic Acid / Q000494:pharmacology; D005750:Gastric Juice / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism*; D006636:Histamine Release / Q000187:drug effects*; D008297:Male; D008785:Metiamide / Q000494:pharmacology; D011763:Pyrrolizidine Alkaloids / Q000494:pharmacology*; D051381:Rats; D011950:Receptors, Cholinergic / Q000187:drug effects; D011968:Receptors, Histamine / Q000187:drug effects
D011763:Pyrrolizidine Alkaloids; D011950:Receptors, Cholinergic; D011968:Receptors, Histamine; C015768:cyngal; D008785:Metiamide; D005707:Gallic Acid; D001285:Atropine
K kharakteristike vliianiia tsingala na zheludochnuiu sekretsiiu krys.