[The anaphylactoid reaction after colloid infusion].
All colloidal volume substitutes carry the risk of anaphylactoid reactions. The general incidence of 0.03% is low; however severe complications can occur. There are differnet pathomechanisms involved in the induction of anaphylactoid reactions after infusion of different colloids. Protein aggregates are of pathogenic importance in human serum albumin incompatibility. The addition of stabilizers to the plasma protein solutions can alter the immunogenicity of the protein molecule. Antibodies of the classes IgG and IgM seem to play a role in severe dextran incompatibility. There was a direct correlation of the intensity of the clinical symptoms with the anti-dextran-antibody titer.
D000707:Anaphylaxis / Q000209:etiology* / Q000628:therapy; D000818:Animals; D001798:Blood Proteins; D003102:Colloids / Q000009:adverse effects*; D003348:Cortisone / Q000627:therapeutic use; D003911:Dextrans; D004837:Epinephrine / Q000627:therapeutic use; D005780:Gelatin; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives; D010952:Plasma Substitutes / Q000009:adverse effects*; D011817:Rabbits
D001798:Blood Proteins; D003102:Colloids; D003911:Dextrans; D006895:Hydroxyethyl Starch Derivatives; D010952:Plasma Substitutes; D005780:Gelatin; D003348:Cortisone; D004837:Epinephrine
Die anaphylaktoide Reaktion nach Kolloid-Infusion.