title: [Controversial and unsolved problems in the prevention of infectious hepatitis].
abstract: Data are presented indicating that 1 ml of 10% and 1% immunoglobulin possessed similar epidemiological activity in the prophylaxis of infectious hepatitis. It was shown that redical action of infectious hepatitis on the epidemic process was possible only in case of embracement by immunoglobulin vaccination of not less than 80% of children aged from 1 to 11 years. The economic effect of the introduction of 1% immunoglobulin constituted about 40 000 roubles per 100 000 persons vaccinated. Besides, a possibility of side-effects were nilin case of placental immunoglobulin since in the 1% preparation nonspecific biologically active substances could penetrate in much lesser amounts.
mesh_terms: D002648:Child; D002675:Child, Preschool; D006525:Hepatitis, Viral, Human / Q000517:prevention & control*; D006801:Humans; D007223:Infant; D010920:Placenta / Q000276:immunology; D012426:Russia; D005719:gamma-Globulins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D005719:gamma-Globulins
vernacular_title: Spornye i nereshennye voprosy profilaktiki infektsionnogo gepatita.