Studies of the HLA complex in families of children with congenital heart disease.
In order to test the hypothesis that HLA-linked developmental determinants are involved in the pathogenesis of congenital heart disease, we performed tissue typing on 10 families in which two or more siblings had cardiac malformations. No association between the occurrence of congenital heart disease and the HLA complex was found.
D000939:Epitopes; D005260:Female; D006680:HLA Antigens; D006330:Heart Defects, Congenital / Q000235:genetics*; D006801:Humans; D008285:Major Histocompatibility Complex; D008297:Male; D010375:Pedigree
D000939:Epitopes; D006680:HLA Antigens