title: [Immunological concentration determinations of the streptokinase preparation Awelysin dissolved in various infusion solutions for its stability evaluation].
abstract: By means of the electro-immuno-assay according to Laurell the decrease of concentration was determined for the streptokinase preparation Awelysin dissolved in various infusion media at 20 degrees C. The stability behaviour of a streptokinase solution of 1.000 IE/ml showed a significant decrease of concentration after 24 hours (alpha less than 5%) as compared with the initial concentration. However, in comparison no significant differences as to the streptokinase stability could be found by using different infusion solutions. At 20 degrees C the decrease of streptokinase concentration may be neglected up to 24 hours in an infusion solution of streptokinase previously prepared.
mesh_terms: D004355:Drug Stability; D006801:Humans; D007106:Immune Sera; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007263:Infusions, Parenteral; D012996:Solutions; D013300:Streptokinase
chemical_list: D007106:Immune Sera; D012996:Solutions; D013300:Streptokinase
vernacular_title: Immunologische Konzentrationsbestimmungen des in verschiedenen Infusionslösungen gelösten Streptokinase-Präparates Awelysin zur Beurteilung der Stabilitätsverhältnisse.