Properties of a goat anti-L antibody: further evidence for heterogeneity of the L antigen.
The preparation and properties of an antibody (anti-L) against low potassium type (LK) goat red cells raised in a high potassium type (HK) goat are described. This reagent stimulated active potassium transport, but showed only weak serological activity against low potassium type (LK) sheep and goat red cells. The results are discussed in relation to the hypothesis that anti-L antibody has two specificities--a sodium pump-stimulating activity (anti-Lp) and a serological activity (anti-L1y).
D000818:Animals; D000918:Antibody Specificity; D001693:Biological Transport, Active / Q000187:drug effects; D000939:Epitopes; D004912:Erythrocytes / Q000276:immunology* / Q000378:metabolism; D006041:Goats / Q000097:blood*; D007518:Isoantibodies; D007519:Isoantigens; D010042:Ouabain / Q000494:pharmacology; D011188:Potassium / Q000097:blood*; D012756:Sheep
D000939:Epitopes; D007518:Isoantibodies; D007519:Isoantigens; D010042:Ouabain; D011188:Potassium