title: Drug risks in pregnancy revisited.
abstract: In the important interface of assuring safe care for the pregnant mother and her developing child that falls to the family physician, current knowledge of drug risks in pregnancy is essential. A recent survey showed that an average of 4.5 drugs are taken throughout the pregnancy. Eighty percent are self-prescribed, and a positive correlation was shown between the incidence of congenital anomalies and drug intake. Numerous recent reports of previously unrecognized fetal complications of commonly prescribed and self-used drugs and heightened public awareness makes it imperative that family physicians know the risk principles of major drug groups and be able to recognize drug-induced symptoms and signs in the older infant as well as in the infant.
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000033:Abortion, Threatened / Q000188:drug therapy; D000700:Analgesics / Q000009:adverse effects; D000863:Antacids / Q000009:adverse effects; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects; D000890:Anti-Infective Agents / Q000009:adverse effects; D000925:Anticoagulants / Q000009:adverse effects; D000927:Anticonvulsants / Q000009:adverse effects; D000959:Antihypertensive Agents / Q000009:adverse effects; D013956:Antithyroid Agents / Q000009:adverse effects; D003276:Contraceptives, Oral / Q000009:adverse effects; D004071:Digitalis Glycosides / Q000009:adverse effects; D004232:Diuretics / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D012739:Gonadal Steroid Hormones / Q000009:adverse effects; D006634:Histamine H1 Antagonists / Q000009:adverse effects; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D007752:Obstetric Labor, Premature / Q000188:drug therapy; D011247:Pregnancy; D019966:Substance-Related Disorders / Q000150:complications; D014149:Tranquilizing Agents / Q000009:adverse effects
chemical_list: D000700:Analgesics; D000863:Antacids; D000889:Anti-Arrhythmia Agents; D000890:Anti-Infective Agents; D000925:Anticoagulants; D000927:Anticonvulsants; D000959:Antihypertensive Agents; D013956:Antithyroid Agents; D003276:Contraceptives, Oral; D004071:Digitalis Glycosides; D004232:Diuretics; D012739:Gonadal Steroid Hormones; D006634:Histamine H1 Antagonists; D007004:Hypoglycemic Agents; D014149:Tranquilizing Agents