Magnesium therapy in neonatal tetany.
104 infants with symptomatic hypocalcaemia were randomly allocated to treatment with calcium gluconate, phenobarbitone, or magnesium sulphate. Infants treated with magnesium sulphate had higher plasma-calcium concentrations after 48 hours' treatment and fewer convulsions during and after the treatment period. Magnesium sulphate is recommended as the treatment of choice in symptomatic neonatal tetany whether or not there is hypomagnesaemia.
D000284:Administration, Oral; D002118:Calcium / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use; D004341:Drug Evaluation; D006801:Humans; D006996:Hypocalcemia / Q000097:blood / Q000150:complications; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000188:drug therapy*; D007273:Injections, Intramuscular; D008274:Magnesium / Q000097:blood; D008278:Magnesium Sulfate / Q000008:administration & dosage / Q000627:therapeutic use*; D010634:Phenobarbital / Q000008:administration & dosage / Q000627:therapeutic use; D010758:Phosphorus / Q000097:blood; D013746:Tetany / Q000188:drug therapy* / Q000209:etiology
D010758:Phosphorus; D008278:Magnesium Sulfate; D008274:Magnesium; D002118:Calcium; D010634:Phenobarbital