title: Existence of 28R-antigen in a certain strain of group F streptococcus.
abstract: An inter-Group common antigen was detected between Group A type 28 (Small)- and Group F (21/58/O'Mahoney, Colindale)-streptococcal cells by the T-typing agglutination reaction. The characteristics of this antigen coincide with those of the 28R-antigen, which was first detected in the Group A type 28 (Small) cells by Lancefield in 1943, in the following points: 1) It can be extracted from the cells with HC1 at pH 2.0 at 100 C in a stable state; 2) It can be kept in a stable state by heating in an alkaline solution at pH 7.8; 3) The antigen on the heat-killed cells was not affected by trypsin digestion at pH 7.8 but was destroyed by pepsin digestion at pH 2.0.
mesh_terms: D000372:Agglutination Tests; D000942:Antigens, Bacterial / Q000032:analysis*; D000939:Epitopes; D013291:Streptococcus / Q000276:immunology*; D013297:Streptococcus pyogenes / Q000276:immunology
chemical_list: D000942:Antigens, Bacterial; D000939:Epitopes