[Alcoholic hyaline-like bodies in nerve cells of the caudate nuclei in various diseases of children].
Intracytoplasmic hyaline bodies were noticed in nerve cells of the caudate nuclei of the infantile diseases: Leigh's encephalomyelopathy (12-year-old, male), Wilson's disease (14-year-old, male), Morquio's disease (12-year-old, male), pseudoulegyric type of hepatocerebral degeneration (19-year-old, male) and Schilder's disease (15-year-old, male). The hyeline bodies were noticed as linear, striate, dendritic or antler-like in form and stained pink or red with hematoxylin-eosin, orange or red with tmasson trichrome, and dark blue or purple with phosphotungstic acid hematoxylin. The characteristics of the neuronal inclusions have much resemblance to the "alcoholic hyaline-like bodies" which were described by K. Kojima in the caudate nuclei of alcoholics. The results may indicate that the presence of the hyaline bodies in the caudate nucleus is not pathognomonic for alcoholic intoxication, but may suggest the presence of a certain common metabolic disorder among the described diseases.
D000293:Adolescent; D000437:Alcoholism / Q000378:metabolism; D002421:Caudate Nucleus / Q000032:analysis* / Q000473:pathology; D002648:Child; D006801:Humans; D006818:Hyalin / Q000032:analysis*; D002479:Inclusion Bodies; D008297:Male