Close genetic relationships between determinants of the HLA-D region detected by MLR-I, MLR-II, and B-lymphocyte serology.
The human Ia equivalent (Ly-Li system) or a very closely linked gene plays a preponderant role in secondary MLR, and also has an additive effect on the intensity of the primary MLR. PLTs developed in Li phenoidentity seem to detect still other determinants.
D000483:Alleles; D001402:B-Lymphocytes / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D008040:Genetic Linkage; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D007959:Lymphocyte Culture Test, Mixed
D000939:Epitopes; D006680:HLA Antigens