title: Experimental infection with Ancylostoma caninum larvae in mice. V. Serum protein pattern during infection with various doses.
abstract: Serum protein patterns of Swiss albino mice during Ancylostoma caninum infection with varying dose levels were studied electrophoretically. There was a significant decrease in albumin associated with a corresponding increase in beta globulin in all the infected groups. Gamma globulin decreased significantly in all groups except the one infected with a challenge dose of 4000 larvae. Maximum changes occurred on day 31, 15, 9, 15 and 6 when mice were infected with 250, 500, 1000, 2000 and 4000 larvae, respectively. There was a significant negative correlation between albumin and the infective doses and a positive correlation between beta globulin and the infective doses and among the changes caused by different infective doses.
mesh_terms: D000510:Alpha-Globulins / Q000378:metabolism; D000722:Ancylostoma / Q000254:growth & development; D000724:Ancylostomiasis / Q000097:blood*; D000818:Animals; D001609:Beta-Globulins / Q000378:metabolism; D004195:Disease Models, Animal; D005260:Female; D007814:Larva / Q000254:growth & development; D008297:Male; D051379:Mice; D012709:Serum Albumin / Q000378:metabolism*; D012712:Serum Globulins / Q000378:metabolism*; D005719:gamma-Globulins / Q000378:metabolism
chemical_list: D000510:Alpha-Globulins; D001609:Beta-Globulins; D012709:Serum Albumin; D012712:Serum Globulins; D005719:gamma-Globulins