title: Effect of sera from cystic fibrosis homozygotes and heterozygotes on glucose metabolism in Vero cells.
abstract: The effect on intracellular production of carbon dioxide from glucose of sera from cystic fibrosis (C.F.) homozygotes and heterozygotes was determined in an established cell line (Vero cell) by a double-blind assay. CO2 production was reduced when cells were incubated with an ammonium-sulphate-precipitated fraction of sera from C.F. homozygotes and heterozygotes but not by a similar fraction from sera of healthy donors.
mesh_terms: D000818:Animals; D002245:Carbon Dioxide; D002460:Cell Line; D003550:Cystic Fibrosis / Q000097:blood* / Q000235:genetics; D005947:Glucose / Q000378:metabolism*; D000882:Haplorhini; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007668:Kidney
chemical_list: D002245:Carbon Dioxide; D005947:Glucose