[Cellular and humoral indicators of antibody formation in rats with liver lesions caused by the antihepatocytotoxic serum].
As revealed, antihepatocitotoxic serum caused a sharp suppression of antibody genesis in rats at the early period (the 3rd day) after its 5 administrations; this was indicated by a marked reduction of the antibody-forming cell count in the spleen and reduction of the circulating antibody titres (hemolysins and hemagglutinins). Along with this, antibody formation was stimulated in the liver in the course of the whole month of study. By the end of the month suppression of antibody formation was replaced by its stimulation.
D000818:Animals; D000917:Antibody Formation; D000921:Antibody-Producing Cells / Q000473:pathology; D002452:Cell Count; D005260:Female; D007106:Immune Sera / Q000008:administration & dosage; D008099:Liver / Q000276:immunology* / Q000473:pathology; D008107:Liver Diseases / Q000276:immunology*; D008198:Lymph Nodes / Q000473:pathology; D011817:Rabbits; D051381:Rats; D013154:Spleen / Q000473:pathology
D007106:Immune Sera
Kletochnye i gumoral'nye pokazateli antitelogeneza u krys pri porazhenii pecheni antigepatotsitotoksicheskoĭ syvorotkoĭ.