title: Serum globulin changes in patients with craniocerebral trauma.
abstract: Investigations of serum total protein, albumin, alpha-1, alpha-2, alpha-2M, beta- and gamma-globulin changes are reported in 48 patients with craniocerebral trauma. Only alpha-2 and alpha-2M globulins showed important variations, the first rising to three to four times normal values (112% on average) and directly correlating with the amount of tissue lesions. Alpha-2M changes were rather irregular with a tendency to severe decrease during the first days in patients with a bad prognosis. Reasons for non-regular changes of alpha-2M are discussed. Alpha-1 globulin showed a similar though less marked increase. Gamma globulin, on average, was diminished in the first week.
mesh_terms: D001609:Beta-Globulins / Q000032:analysis*; D001798:Blood Proteins / Q000032:analysis; D001930:Brain Injuries / Q000097:blood*; D006259:Craniocerebral Trauma / Q000097:blood*; D005260:Female; D006406:Hematoma / Q000097:blood; D006801:Humans; D008297:Male; D011379:Prognosis; D012709:Serum Albumin / Q000032:analysis; D013997:Time Factors; D005719:gamma-Globulins / Q000032:analysis
chemical_list: D001609:Beta-Globulins; D001798:Blood Proteins; D012709:Serum Albumin; D005719:gamma-Globulins