Antibody-like activity to polyacrylic acid in normal rabbit sera.
Most unimmunized rabbit sera agglutinate acrylic particles coated with polyacrylic acid. The factor responsible for the agglutinating activity turned out to be a 2-mercaptoethanol-resistent immunoglobulin, present in low concentration. It was tentatively classified as "natural antibody". This is assumed to have arisen upon previous contact with naturally occurring cross-reacting polyanions.
D000179:Acrylates / Q000276:immunology*; D000371:Agglutination / Q000187:drug effects; D000818:Animals; D000906:Antibodies; D011817:Rabbits / Q000276:immunology; D013386:Succinates / Q000494:pharmacology; D005719:gamma-Globulins
D000179:Acrylates; D000906:Antibodies; D013386:Succinates; D005719:gamma-Globulins