The specificity of heterologous antiserum against brain of nude mice.
Serum prepared in rabbits against brain of nude mice was tested for its T-cell specificity by immunoperoxidase staining. The difference in activity of this anti-brain serum against early precursors and more differentiated precursors of the haemopoietic cell lines was investigated by CFU-s and CFU-c determination after serum incubation. The results showed that the activity of the anti-nude brain serum is completely comparable to serum prepared against brain of normal mice.
D000818:Animals; D000918:Antibody Specificity; D000961:Antilymphocyte Serum; D001921:Brain / Q000276:immunology*; D003114:Colony-Forming Units Assay; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D006412:Hematopoietic Stem Cells / Q000276:immunology; D007124:Immunoenzyme Techniques; D051379:Mice; D008815:Mice, Inbred Strains; D008819:Mice, Nude / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D000961:Antilymphocyte Serum; D000939:Epitopes