title: Group-specific human granulocyte antigens on a chronic myelogenous leukemia cell line with a Philadelphia chromosome marker.
abstract: Group-specific human granulocyte antigens are serologically detectable with granulocytotoxic-positive human alloantisera on a cell line, K562, of chronic myelogenous leukemia origin which bears a Philadelphia chromosomal marker. The same cell line lacks serologically detectable HLA, B2 microglobulin, and B-lymphocyte antigens. Granulocyte antigens are important cell markers for cell lines of suspected myeloid lineage.
mesh_terms: D000941:Antigens; D001402:B-Lymphocytes / Q000276:immunology; D002460:Cell Line; D002869:Chromosome Aberrations; D002904:Chromosomes, Human, 21-22 and Y; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D006098:Granulocytes / Q000276:immunology*; D006680:HLA Antigens; D006801:Humans; D007163:Immunosorbent Techniques; D007951:Leukemia, Myeloid / Q000276:immunology*; D007962:Leukocytes / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000941:Antigens; D000939:Epitopes; D006680:HLA Antigens