title: Effect of lindane on pregnancy in the rabbit and rat.
abstract: There was no evidence of any teratogenic effect of lindane when administered during pregnancy at levels equivalent to 5, and 15 mg/kg body weight to New Zealand White rabbits from days 6 to 18 inclusive, or to CFY rats from days 6 to 16 inclusive. These findings are consistent with the negative teratogenicity results in mice mutagenicity studies and 3-generation rat reproduction studies already reported.
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D005333:Fetus / Q000187:drug effects*; D001556:Hexachlorocyclohexane / Q000633:toxicity*; D009929:Organ Size / Q000187:drug effects; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D011817:Rabbits; D051381:Rats; D012272:Ribs / Q000002:abnormalities
chemical_list: D001556:Hexachlorocyclohexane