Endotoxins of anaerobic gram-negative rods.
Endotoxic lipopolysaccharides (LPS) isolated from Fusobacterium are similar to those of Salmonella with respect to chemical composition, O-antigenic specificity and endotoxic activity. Bacteroides LPS are highly atypical with respect to the chemical composition, and their endotoxic activity is low. O-Antigenic specificity is present. B. fragilis LPS is chemotactic for polymorphonuclear leukocytes in vitro and in vivo. The chemotactic activity is brought about by activation of the alternative complement pathway.
D000818:Animals; D000942:Antigens, Bacterial; D001439:Bacteroides / Q000032:analysis; D001441:Bacteroides fragilis / Q000032:analysis; D002634:Chemotaxis, Leukocyte; D004731:Endotoxins / Q000032:analysis* / Q000302:isolation & purification; D000939:Epitopes; D005673:Fusobacterium / Q000032:analysis; D006089:Gram-Negative Anaerobic Bacteria / Q000032:analysis*; D006168:Guinea Pigs; D008070:Lipopolysaccharides / Q000032:analysis* / Q000302:isolation & purification; D051379:Mice; D011135:Polysaccharides, Bacterial / Q000032:analysis* / Q000302:isolation & purification; D011817:Rabbits; D012477:Salmonella enteritidis / Q000032:analysis; D014678:Veillonella / Q000032:analysis
D000942:Antigens, Bacterial; D004731:Endotoxins; D000939:Epitopes; D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial