Type C oncornavirus isolation studies in systemic lupus erythematosus. III. Isolation of a putative retravirus by triple cell fusion.
A putative retravirus was isolated from a cell culture derived by fusion of mink and dog cell lines with cultured placental cells from a patient with systemic lupus erythematosus. The virus was detected by reverse transcriptase assay of supernatant medium after prolonged subculturing. Its characterisation, including species of origin, is in progress, but it is probably a new type C virus. Its role, if any, in lupus erythematosus in unknown.
D002460:Cell Line; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000382:microbiology*; D008828:Microbiological Techniques; D012194:RNA-Directed DNA Polymerase / Q000032:analysis; D012190:Retroviridae / Q000201:enzymology / Q000302:isolation & purification*; D014779:Virus Replication
D012194:RNA-Directed DNA Polymerase