Increase in leg blood-flow by normovolaemic haemodilution in intermittent claudication.
Normovolaemic haemodilution down to a packed-cell volume of 35% was done in 10 patients with stable intermittent claudication. For a mean reducation in the packed-cell volume of 21.5% there was a 170% increase in peak calf blood-flow and a 111% increase in haemoglobin delivery. 7 of the 10 patients reported an increased walking distance. Normovolaemic haemodilution may be of use in the management of some patients with peripheral vascular disease.
D000368:Aged; D001775:Blood Circulation; D001810:Blood Volume; D005260:Female; D006400:Hematocrit; D006438:Hemodilution; D006454:Hemoglobins / Q000032:analysis / Q000502:physiology; D006801:Humans; D007383:Intermittent Claudication / Q000503:physiopathology / Q000628:therapy*; D007866:Leg / Q000098:blood supply*; D008124:Locomotion; D008297:Male; D008875:Middle Aged; D012039:Regional Blood Flow
D006454:Hemoglobins