title: Soybean-protein diet in the treatment of type-II hyperlipoproteinaemia.
abstract: A soybean textured protein induced a 14% decrease of plasma-cholesterol levels after two weeks and 21% after three when substituted for animal proteins in a group of 20 patients with type-II hyperlipoproteinaemia. Comparison of soybean diet with a standard low-lipid diet in the same patients, according to a cross-over protocol, indicated that this hypocholesterolaemic effect was not due to differences in the lipid composition of the two diets. The hypothesis that a soy protein has a hypocholesterolaemic action per se is supported by the results of a subsequent experiment in 8 type-II patients in whom the addition of cholesterol (500 mg/day) to soy protein did not modify the hypocholesterolaemic response.
mesh_terms: D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood; D002791:Cholesterol, Dietary / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D004041:Dietary Fats / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000178:diet therapy*; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D014674:Plant Proteins, Dietary / Q000008:administration & dosage / Q000627:therapeutic use*; D013025:Glycine max; D014280:Triglycerides / Q000097:blood
chemical_list: D002791:Cholesterol, Dietary; D004041:Dietary Fats; D004044:Dietary Proteins; D008077:Lipoproteins, LDL; D014674:Plant Proteins, Dietary; D014280:Triglycerides; D002784:Cholesterol