title: Cerebral atrophy. An immunological disorder?
abstract: Patients with cerebral atrophy of unknown origin, patients with nuclear forms of schizophrenia or neurosis, and normal subjects were skin-tested with human brain and liver proteins. The frequency of positive delayed skin-sensitivity reactions to brain proteins was significantly higher in the cerebral-atrophy group than in other groups, thus suggesting a correlation between cerebral atrophy and cell-mediated immunity.
mesh_terms: D000328:Adult; D000818:Animals; D001284:Atrophy; D001327:Autoimmune Diseases / Q000150:complications* / Q000175:diagnosis; D001921:Brain / Q000473:pathology*; D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000276:immunology; D009497:Neurotic Disorders / Q000209:etiology; D051381:Rats; D012559:Schizophrenia / Q000209:etiology; D012882:Skin Tests
chemical_list: D009419:Nerve Tissue Proteins