[The problem of hepatic dysfunction of the diagnosis of hypernephroid kidney carcinomas (Stauffer syndrome)].
In 43 patients with histologically proved hypernephroid kidney cancer evaluation of the electrophoretic results, serum alkaline phosphatase, thromboplastin time (Quick's time) and bromthalein retention (n = 10) was carried out. As a control group the serum values of 10 patients with clinical tentative diagnosis of hypernephroid kidney cancer were checked; in this group operation and histological examination showed no kidney tumor. Only in one patient we found the typical constellation with elevated alkaline phosphatase, diminished albumin, elevated alpha-2 globuline fraction, and decreased thromboplastin time. 10 patients with histologically proved hypernephroid kidney cancer (nephrectomy) did not show any hepatic dysfunctions. Concerning the laboratory findings there was no difference between the two groups. In case of hepatic dysfunctions of unknown etiology a liver punction should be carried out for histologically examination. The cause of hepatic dysfunction (Stauffer syndrome) in cases of hypernephroid kidney cancer are discussed.
D000469:Alkaline Phosphatase / Q000378:metabolism; D000510:Alpha-Globulins / Q000032:analysis; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis*; D008099:Liver / Q000503:physiopathology; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012709:Serum Albumin / Q000032:analysis; D013448:Sulfobromophthalein / Q000378:metabolism
D000510:Alpha-Globulins; D012709:Serum Albumin; D013448:Sulfobromophthalein; D000469:Alkaline Phosphatase
Zur Problematik hepatischer Dysfunktionen in der Diagnostik hypernephroider Nierenkarzinome (Stauffer-Syndrom).