title: [Infectious toxic hypotension--effect and dosage of midodrine (author's transl)].
abstract: A new alpha-sympathicomimetic drug with peroral effect is midodrine. The effective oral dosage in infancy and childhood is 0.06 mg/kg/dosi. The therapeutic effect, comparing the drug with etilefrin is shown in 120 children with pneumonia, enteritis, meningitis in a random study. The results give an increase in blood pressure and a decrease in heart frequency, statistically proved, on the first day of treatment. Therefore it seems that midodrine is qualified for the treatment of hypotension in infectious diseases.
mesh_terms: D001424:Bacterial Infections / Q000150:complications*; D001794:Blood Pressure / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004983:Ethanolamines / Q000627:therapeutic use*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007022:Hypotension / Q000188:drug therapy* / Q000209:etiology; D007223:Infant; D008297:Male; D008879:Midodrine / Q000627:therapeutic use*; D012772:Shock, Septic / Q000150:complications* / Q000209:etiology
chemical_list: D004983:Ethanolamines; D008879:Midodrine
vernacular_title: Infektiös-toxische Hypotension -- Dosierung und Wirkung von Midodrin.