title: Anesthetic practice and pregnancy. Controlled survey of male anaesthetists in the United Kingdom.
abstract: 7949 male doctors in the U.K. were surveyed to determine whether there was a relation between operating-theatre work (exposure) and abnormalities in the obstetric history of their marriages. Paternal exposure did not appear to influence the overall abortion-rate or the frequency of major congenital abnormality and involuntary infertility. The frequency of minor congenital abnormality in the children of exposed fathers was 3.09% compared with 2.35% (non-exposed). Maternal exposure was associated with a 15.5% frequency of abortion. Matching of exposed and non-exposed pregnancies with respect to birth order, maternal age, and smoking-habits suggests that the risk of abortion may increase by 158% to 271% with maternal exposure.
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000022:Abortion, Spontaneous / Q000139:chemically induced*; D000776:Anesthesiology; D000777:Anesthetics / Q000009:adverse effects*; D004781:Environmental Exposure; D005260:Female; D005313:Fetal Death / Q000139:chemically induced; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D009873:Operating Rooms; D011247:Pregnancy; D012306:Risk; D012737:Sex Factors; D006113:United Kingdom
chemical_list: D000777:Anesthetics