title: Post-natal development of brown adipose tissue in the rat bred at 23 degrees C or 28 degrees C.
abstract: In view to study the effects of thermal environment on the development and the thermogenic activity of interscapular brown adipose tissue (BAT), young rats born at 23 degrees C or 28 degrees C were sacrificed at 1, 3, 7, 11, 14 or 21 days after birth. The rate of increase in animal weight was quite the same at both temperatures up to the 14th day. The development of BAT and its contents in lipids, in water and in noradrenaline indicate that the energetic activity of the tissue is greatly stimulated in rats kept at 23 degrees C up to the 11th day. It is concluded that in rats bred in the habitual thermal conditions (23 degrees C), the occurrence of non shivering thermogenesis (NST) is important during the period of ten days after birth; in the following period NST could be progressively replaced by other thermoregulatory processes.
mesh_terms: D002001:Adipose Tissue, Brown / Q000254:growth & development* / Q000378:metabolism; D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D001833:Body Temperature Regulation; D005260:Female; D005333:Fetus; D050356:Lipid Metabolism; D009638:Norepinephrine / Q000378:metabolism; D009929:Organ Size; D011247:Pregnancy; D051381:Rats; D013696:Temperature
chemical_list: D009638:Norepinephrine