Changes in enzyme levels in the testis and liver of the 13-lined ground squirrel (spermophilus tridecemlineatus) at the time of arousal from hibernation.
Male 13-lined ground squirrels induced to emerge from hibernation resumed feeding and gained weight. The weight gain was supported by increases in the levels of glucose 6-phosphate dehydrogenase, L-alanine aminotransferase and carnitine acetyltransferase in the liver. Maturation of the testis occurred in a period of about 16 days spanning the time of induced arousal. The testes of hibernating males were characterized by higher levels of L-alanine aminotransferase, glucose 6-phosphate dehydrogenase and 3-hydroxyacyl-CoA dehydrogenase than the testes of aroused males. Hexokinase, carnitine acetyltransferase and citrate synthase levels were similar in the testes of hibernating and aroused males. 3-Hydroxyacyl-CoA dehydrogenase was more active and L-alanine aminotransferase less active in ground squirrel sperm than in rat sperm.
D000222:Adaptation, Physiological; D000410:Alanine Transaminase / Q000378:metabolism; D000429:Alcohol Oxidoreductases / Q000378:metabolism; D000818:Animals; D001143:Arousal; D001835:Body Weight; D002332:Carnitine O-Acetyltransferase / Q000378:metabolism; D002950:Citrate (si)-Synthase / Q000378:metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006593:Hexokinase / Q000378:metabolism; D006605:Hibernation; D006880:Hydroxy Acids; D008099:Liver / Q000201:enzymology*; D008297:Male; D009929:Organ Size; D012377:Rodentia / Q000502:physiology*; D012589:Sciuridae / Q000502:physiology*; D013737:Testis / Q000033:anatomy & histology / Q000201:enzymology*; D013997:Time Factors
D006880:Hydroxy Acids; D000429:Alcohol Oxidoreductases; D005954:Glucosephosphate Dehydrogenase; D002332:Carnitine O-Acetyltransferase; D002950:Citrate (si)-Synthase; D000410:Alanine Transaminase; D006593:Hexokinase