Steroidal compounds (injectable and implants) affecting spermatogenesis in men.
The effect of androgen and different progestins on spermatogenesis was studied in young men with subfertility, prostatovesiculitis and haematospermia, and in older men with benign hypertrophy of the prostate. The compounds (testosterone, testosterone oenanthate, ethinyl oestradiol, megestrol acetate, ethinyl norgestrienone and Depo-Provera) were administered intramuscularly, orally or as subcutaneous silastic implants.
D000328:Adult; D000368:Aged; D000728:Androgens / Q000494:pharmacology*; D004343:Drug Implants; D004958:Estradiol / Q000097:blood; D004997:Ethinyl Estradiol / Q000494:pharmacology; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy; D007273:Injections, Intramuscular; D007985:Leydig Cells / Q000187:drug effects; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008525:Medroxyprogesterone / Q000494:pharmacology; D008535:Megestrol / Q000494:pharmacology; D008875:Middle Aged; D009645:Norgestrienone / Q000494:pharmacology; D011372:Progestins / Q000494:pharmacology*; D011470:Prostatic Hyperplasia / Q000188:drug therapy; D013091:Spermatogenesis / Q000187:drug effects*; D013737:Testis / Q000473:pathology; D013739:Testosterone / Q000097:blood / Q000494:pharmacology
D000728:Androgens; D004343:Drug Implants; D011372:Progestins; D013739:Testosterone; D004997:Ethinyl Estradiol; D004958:Estradiol; D009645:Norgestrienone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D008535:Megestrol; D008525:Medroxyprogesterone