Inappropriate antihypertensive therapy in the elderly.
Six symptomless patients aged 64-84 (mean 72) years received antihypertensive therapy from their family doctors. Pretreatment systolic pressures ranged from 160 to 220 mm Hg and disastolic pressures from 80 to 120 mm Hg. Within one week of starting therapy all six patients were admitted as emergencies with epidoses of unconsciousness. Admission systolic pressures ranged from 80 to 150 mm Hg and diastolic pressures from 50 to 90 mm Hg. Before admission each patient had experiences symptoms of postural hypotension and had become housebound. After antihypertensive therapy was stopped, one patient had a residual left homonymous hemianopia but the others recovered completely. A raised systolic and distolic pressure is common in the elderly; potent antihypertensive treatment may seriously impair the quality of life and is often unecessary.
D000367:Age Factors; D000368:Aged; D000959:Antihypertensive Agents / Q000009:adverse effects*; D003518:Cyclopenthiazide / Q000009:adverse effects / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D007024:Hypotension, Orthostatic / Q000139:chemically induced*; D008750:Methyldopa / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D010096:Oxprenolol / Q000009:adverse effects / Q000627:therapeutic use; D011189:Potassium Chloride / Q000009:adverse effects / Q000627:therapeutic use
D000959:Antihypertensive Agents; D010096:Oxprenolol; D008750:Methyldopa; D011189:Potassium Chloride; D003518:Cyclopenthiazide