[Detection of humoral antibodies to species-specific and group ornithosis antigens in the dynamics of the infection].
The time course of antibody production to group- and species-specific antigens of ornithosis agent was studied by complement fixation (CFT) and hemagglutination-inhibition (HI) tests. In rabbits after a single intravenous inoculation of the ornithosis agent, antibody to the homologous species-specific antigen appeared in the peripheral blood 3--5 days after inoculation and reached maximum levels during the 1-st week, and to the group-specific antigen could be detected 3--5 days after inoculation but reached maximum titers only 3--4 weeks later. In practical serological diagnosis of ornithosis and other chlamydia infections, the group antigen is used which gives retrospective diagnosis at 10--14 days or later. The results of the study suggest that the use of CFT with the species-specific antigen will not only differentiate ornithosis from other chlamydial infections but also will permit early serological diagnosis of ornithosis.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis*; D002645:Chickens; D002691:Chlamydophila psittaci / Q000276:immunology*; D003168:Complement Fixation Tests; D006224:Cricetinae; D000939:Epitopes; D006168:Guinea Pigs; D006385:Hemagglutination Inhibition Tests; D007109:Immunity; D007114:Immunization; D008297:Male; D008647:Mesocricetus; D009956:Psittacosis / Q000276:immunology*; D011817:Rabbits; D013045:Species Specificity; D013997:Time Factors
D000907:Antibodies, Bacterial; D000939:Epitopes
Obnaruzhenie gumoral'nykh antitel k vidospetsificheskomu i gruppovomu antigenam ornitoza v dinamike infektsii.