Failure of transfer factor therapy in atopic dermatitis.
A controlled clinical study was conducted on 6 patients with atopic dermatitis to assess the efficacy of transfer factor. After the code was broken the 3 patients treated with placebo preparation were treated with transfer factor for a further period of 10 weeks. No definite therapeutic effects could be demonstrated. The immunological in vivo and in vitro tests failed to reveal any effects except for a change to positive in the tuberculin skin test in those patients who had previously been skin test negative. The treatment had to be discontinued in one patient due to a suspected allergic reaction against transfer factor.
D000328:Adult; D002986:Clinical Trials as Topic; D003876:Dermatitis, Atopic / Q000188:drug therapy* / Q000276:immunology; D004311:Double-Blind Method; D003875:Drug Eruptions; D004341:Drug Evaluation; D006801:Humans; D007158:Immunologic Techniques; D008297:Male; D014165:Transfer Factor / Q000009:adverse effects / Q000627:therapeutic use*
D014165:Transfer Factor