Combined surgery and chemotherapy for retroperitoneal metastases of testicular carcinomas other than pure seminoma.
The results of treatment in 210 patients with testicular carcinomas other than pure seminoma are analysed. Patients with negative retroperitoneal nodes had a very good prognosis following lymph node dissection alone. Patients with positive nodes did much better after adjunctive chemotherapy than after post-operative irradiation. Patients with advanced disease showed significant improvement with intensive chemotherapy combined with surgery. Presently retroperitoneal lymphadenectomy combined with intensive chemotherapy seems to be the treatment of choice for metastatic testicular carcinomas.
D001761:Bleomycin / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D011183:Postoperative Complications; D011379:Prognosis; D012186:Retroperitoneal Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D013736:Testicular Neoplasms / Q000473:pathology*; D014747:Vinblastine / Q000009:adverse effects / Q000627:therapeutic use
D001761:Bleomycin; D014747:Vinblastine