Silver deposition in mouse glomeruli.
Administration of 6 mM silver nitrate in the drinking water of mice resulted in deposition within the glomerular basement membrane of silver granules which were detected on electron microscopy after 12 days. Larger aggregates were detected in the basement membrane and mesangium when silver ingestion was extended to 14 weeks. The silver deposits did not alter significantly over a period of 21 weeks after silver nitrate ingestion was stopped.
D000818:Animals; D001485:Basement Membrane / Q000378:metabolism / Q000648:ultrastructure; D007678:Kidney Glomerulus / Q000378:metabolism* / Q000648:ultrastructure; D051379:Mice; D012834:Silver / Q000378:metabolism*; D012835:Silver Nitrate / Q000008:administration & dosage; D013194:Staining and Labeling
D012834:Silver; D012835:Silver Nitrate