Detection and measurement of fetomaternal haemorrhage: serum alpha-fetoprotein and the Kleihauer technique.
A raised maternal serum alpha-fetoprotein concentration was taken as an indicator of fetomaternal haemorrhage due to amniocentesis and was used to calculate the volume of the fetal bleed. The alpha-fetoprotein concentration seemed to be a more sensitive and reliable indicator than the established Kleihauer technique and may have further applications in antenatal testing.
D000649:Amniocentesis / Q000009:adverse effects; D004906:Erythrocyte Count; D005260:Female; D005312:Fetal Blood; D005331:Fetomaternal Transfusion / Q000097:blood* / Q000209:etiology; D006801:Humans; D011247:Pregnancy; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins