[Activation by means of various adsorbents. (Contribution to the mechanism of contact activation of the blood coagulation process)].
20 different adsorbing substances were examined for the purpose of determining physico-chemical parameters influencing the contact activation in the partial thromboplastin time (PTT). In the course of these examinations the prerequisites for the process under way were found to exist in a low adsorbing activity of the substance used as a surface and in the reversibility of adsorption. The effect activating the contact will depend on surface conditions and to a lesser degree on its size. An even crystal structure and the size of particles will have a positive influence on the surface properties and thus on the effect activating the contact.
D000327:Adsorption; D001777:Blood Coagulation; D001798:Blood Proteins / Q000032:analysis; D002118:Calcium / Q000097:blood; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D010316:Particle Size; D013499:Surface Properties; D013925:Thromboplastin / Q000032:analysis
D001798:Blood Proteins; D005340:Fibrinogen; D013925:Thromboplastin; D002118:Calcium
Zur Aktivierung mit verschiedenen Adsorbentien bei Koagulationsuntersuchungen (Beitrag zum Mechanismus der Kontaktaktivierung des Blutgerinnungsprozesses).