Metastatic orchioblastoma: alpha1-fetoprotein in diagnosis and combination chemotherapy in treatment: a case report.
A case in which orchioblastoma metastasised to a lymph node at the left renal hilum is described. The metastasis was not detected by bipedal lymphography, but was associated with a rise in the serum level of the alpha1-fetoprotein. The metastasis responded to combination chemotherapy, including adriamycin, and residual tumour was excised at laparotomy. Tumour regression was associated with a fall in serum alpha1-fetoprotein which may be of value as a tumour marker substance in the diagnosis and monitoring of therapy in this tumour.
D004317:Doxorubicin / Q000009:adverse effects; D004359:Drug Therapy, Combination; D004407:Dysgerminoma / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007223:Infant; D008297:Male; D009362:Neoplasm Metastasis; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000188:drug therapy; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins; D004317:Doxorubicin