A peculiar lymph node anti-carcinoma reaction.
A case of a laryngeal extensive carcinoma determining a severe obstruction is reported, where the development of a monstrous adenopathy is followed by the regression of the initial tumour until complete laryngoscopical disappearance, as well as of obstructive and general symptoms. Cytological and histological examinations of the above-mentioned lymph node demonstrated (besides metastatic cells) a peculiar cellular reaction, similar to rhinoscleroma, which represented an original anti-carcinoma defensive mode. The medical importance of this very rare case is discussed and the probable immune origin of this reactive cellular complex is explained by analogy with "Hodgkinom", where granuloma are the immune response of the body against Sternberg-Reed cell.
D006644:Histiocytes / Q000276:immunology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications*; D008199:Lymphadenitis / Q000209:etiology / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009365:Neoplasm Regression, Spontaneous; D010587:Phagocytosis; D010950:Plasma Cells