title: Electrochemical properties of polycyclic compounds studied by the polarographic method in anhydrous systems. IV. Polarographic study of carcinogenic and noncarcinogenic hydrocarbons in ethylenglycolmonomethylether.
abstract: An experiment was carried out to determine whether there is any correlation between the values of polarographic reduction potentials of polycyclic hydrocarbons and their carcinogenic activity. A comparison of half-wave potentials of polarographic wave I and II of pyrene benzologs revealed that the carcinogenic ones become reduced in ethylenglycolmonomethylether on a mercury dropping electrode at more positive potentials than the inactive benzo- and dibenzopyrenes. The discussion bears both on the reduction mechanism of the compounds and on the relationship between the half-wave potentials and the absorption electron spectra measured in the same solvent.
mesh_terms: D001580:Benzopyrenes / Q000032:analysis; D002273:Carcinogens / Q000032:analysis*; D004563:Electrochemistry; D005026:Ethylene Glycols / Q000494:pharmacology*; D011048:Polarography; D011083:Polycyclic Compounds / Q000032:analysis*; D013054:Spectrophotometry, Atomic
chemical_list: D001580:Benzopyrenes; D002273:Carcinogens; D005026:Ethylene Glycols; D011083:Polycyclic Compounds