[The reactivity of the anticoagulatory system in sympathectomized animals under stress conditions due to acoustic trauma].
In rats of kind of Kruschinskij-Molodkina the number of cells in the stellate ganglion was diminished to 0.5% of the norm after eliminating the sympathetic tonus by means of guanethidine. These animals died of cardiac thrombosis during stress situations. This thrombosis cannot be explained by adrenalin, corticosteroids or thromboplastin spreading in the blood stream. A factor, the nature of which has still to be explained, may be assumed to be responsible for thrombosis to develop during stress situations in animals whose sympathetic tonus has been eliminated by guanethidine.
D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D000818:Animals; D006145:Guanethidine / Q000494:pharmacology*; D006317:Hearing Loss, Noise-Induced; D051381:Rats; D013564:Sympathetic Nervous System / Q000187:drug effects*; D013927:Thrombosis / Q000209:etiology*
D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D006145:Guanethidine
Die Reaktivität des antikoagulatorischen Systems desympathisierter Tiere unter den Bedingungen eines durch akustische Reizung hervorgerufenen Stress