[Evidence of protein kinase activity in 2 murine oncornaviruses].
A protein kinase activity has been detected in two strains of murine Oncornaviruses, MSV/MLV and EFV. This activity phosphorylates not only endogenous viral proteins but also exogenous substrates (histones and phosvitin). The stimulation of enzyme activity by detergents along with the increase of specific activity in viruses treated with trypsin during purification suggest that the enzyme is located in the viral particle.
D017988:Gammaretrovirus / Q000201:enzymology*; D009052:Leukemia Virus, Murine / Q000201:enzymology; D008970:Molecular Weight; D011494:Protein Kinases / Q000378:metabolism*; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D009053:Sarcoma Viruses, Murine / Q000201:enzymology; D013045:Species Specificity; D014357:Trypsin
D011494:Protein Kinases; D012194:RNA-Directed DNA Polymerase; D014357:Trypsin
Mise en évidence d'une activité protéine kinase dans 2 oncornavirus murins.