[Cytospectrophotometric study of glycoproteins of the erythrocyte membrane in renal and spontaneous hypertension in rats].
Spontaneously hypertensive rats (SHR), aged 10 weeks, and rats with renovascular hypertension (25-30 weeks) demonstrated, in contrast to the controls, a different pattern of erythrocytes staining with paraldehyde-fuchsin used in histochemistry for demonstrating glycoproteids. The erythrocytes were found to respond to intravenous glucose injections by changing the optic density. The erythrocytes response of SHR differs from the normals, but no difference was revealed in rats with renovascular hypertension. The authors suggest that the changes in the tinctorial properties of the erythrocytes with reference to paraldehyde-fuchsin indirectly reflect the state of the insulin receptors of the erythrocyte membrane.
D000818:Animals; D004910:Erythrocyte Membrane / Q000032:analysis*; D004912:Erythrocytes / Q000032:analysis*; D005947:Glucose / Q000494:pharmacology; D006023:Glycoproteins / Q000097:blood*; D006973:Hypertension / Q000097:blood*; D006977:Hypertension, Renal / Q000097:blood; D007328:Insulin / Q000097:blood; D008297:Male; D010242:Paraldehyde; D051381:Rats; D011972:Receptor, Insulin; D013053:Spectrophotometry / Q000379:methods; D013194:Staining and Labeling
D006023:Glycoproteins; D007328:Insulin; D011972:Receptor, Insulin; D005947:Glucose; D010242:Paraldehyde
Tsitospectrofotometricheskoe izuchenie glikoproteidov membrany eritrotsitov pri pochechnoĭ i spontannoĭ gipertonii u krys.