Protective effect of dietary fibre against chemically induced bowel tumours in rats.
101 rats were fed one of four diets containing graded amounts of dietary fibre. Subcutaeous dimethylhydrazine (D.M.H.) was given to half the rats in each of the diet groups. Stool mass was found to be directly related to the amount of dietary fibre consumed, and the incidence of D.M.H.-induced colon carcinoma was reduced as dietary fibre increased.
D000821:Animal Feed / Q000032:analysis; D000818:Animals; D002482:Cellulose / Q000627:therapeutic use*; D003110:Colonic Neoplasms / Q000139:chemically induced / Q000453:epidemiology / Q000517:prevention & control*; D004043:Dietary Fiber / Q000627:therapeutic use*; D004127:Dimethylhydrazines; D008297:Male; D009374:Neoplasms, Experimental / Q000453:epidemiology / Q000517:prevention & control; D051381:Rats
D004043:Dietary Fiber; D004127:Dimethylhydrazines; D002482:Cellulose