[The pathogenesis of postoperative abdominal wound dehiscence. Part II: Hemostasiological checks during the course in selected patient groups (author's transl)].
By reference to clinically established risk factors, patients with an increased tendency to disturbances of wound healing were selected and investigated hemostasiologically in a prospective study. Abdominal wound dehiscence occurred postoperatively in 12 of the 28 patients selected clinically as being endangered. In all collectives the Factor XIII concentration fell postoperatively and remained low in the patients with a wound rupture, whereas it rose significantly in patients with undisturbed wound healing. Connections between hemostasis and wound healing are discussed.
D000009:Abdominal Muscles; D000991:Antithrombins / Q000032:analysis; D001779:Blood Coagulation Factors / Q000032:analysis; D005169:Factor VIII / Q000032:analysis; D005176:Factor XIII / Q000032:analysis; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D007813:Laparotomy; D008297:Male; D011446:Prospective Studies; D011517:Prothrombin Time; D012306:Risk; D013529:Surgical Wound Dehiscence / Q000097:blood / Q000209:etiology*; D013530:Surgical Wound Infection / Q000150:complications; D014945:Wound Healing; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000511:alpha-Macroglobulins / Q000032:analysis
D000991:Antithrombins; D001779:Blood Coagulation Factors; D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins; D005169:Factor VIII; D005340:Fibrinogen; D005176:Factor XIII
Zur Pathogenese der postoperativen Bauchwandruptur. Teil II: Hämostaseologische Verlaufskontrollen bei ausgewählten Patientengruppen.