Evidence for two series of B-cell antigens in man and their comparison with HLA-D.
Population and family studies of five sera with antibodies against B-cell determinants show an excellent fit of some of them with the HLA-D determinants, suggesting that the HLA-D determinants themselves or closely linked structures can be recognized by serology. One serum, Ag, might be coded for by a locus different from HLA-D, which could be located between HLA-A and -B. A two-color fluorescence test to detect B-cell antigens was used and found to save time and reagents and to give very good results.
D001402:B-Lymphocytes / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006649:Histocompatibility Antigens / Q000032:analysis; D006650:Histocompatibility Testing; D006801:Humans; D007106:Immune Sera; D008297:Male
D000939:Epitopes; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D007106:Immune Sera