title: [Correlation of alpha-2 pregnancy associated glycoprotein with the clinical course of bronchial carcinoma (author's transl)].
abstract: Alpha-2 pregnancy associated glycoprotein is a high molecular, carbohydrate containing plasma protein with unknown biological function. During clinical treatment of 25 patients with bronchial carcinoma alpha-2 PAG was measured by the electroimmuno-diffusion method according to Laurell. A good correlation was observed between alpha-2 PAG serum levels and the course of the disease in 21 patients. Patients whose course of disease could not be influenced therapeutically showed continously increasing levels of alpha-2 PAG; patients who responded to therapy, showed a significant decrease in alpha-2 PAG serum levels. These findings indicate that periodic determinations of serum alpha-2 PAG may be helpful for controlling the course of bronchial carcinoma.
mesh_terms: D000368:Aged; D001984:Bronchial Neoplasms / Q000188:drug therapy / Q000276:immunology* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D005779:Immunodiffusion; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D000511:alpha-Macroglobulins / Q000032:analysis*
chemical_list: D000511:alpha-Macroglobulins
vernacular_title: Alpha-2 schwangerschaftsassoziiertes Glykoprotein (Alpha-2 PAG). Bestimmungen zur Verlaufskontrolle des Bronchialkarzinoms.