title: Experimental gerontology and quantitative cytology: a new approach to cellular ageing.
abstract: The application of the followiny cytologic methods for gerontological basis research is discussed: 1. Quantitative cytomorphology including electron microscopic morphometry and its combination with cytochemical reactions. 2. Histochemical studies on cell components like DNA in situ by means of acridine orange microfluorimetry and thermal denaturation. 3. X-ray microanalysis for measuring the intranuclear electrolyte contents. The results obtained indicate the usefulness and the validity of a quantitative cytological approach to the cellular ageing.
mesh_terms: D000166:Acridines; D000375:Aging; D002467:Cell Nucleus / Q000032:analysis; D002468:Cell Physiological Phenomena; D003584:Cytological Techniques; D004573:Electrolytes / Q000032:analysis; D004577:Electron Probe Microanalysis; D006801:Humans; D013194:Staining and Labeling
chemical_list: D000166:Acridines; D004573:Electrolytes