Increased arterial-tissue cholesterol after intestinal bypass in severe obesity.
Cholesterol content was measured in biopsy specimens of mesenteric artery taken at the time of jejuno-ileal bypass from 4 very obese patients aged 19, 22, 27, and 42. When their body-weight had become stable (mean 22 months) after operation, biopsy specimens of the temporal artery were obtained from 3 patients and of a mesenteric artery from 1. Cholesterol content had increased significantly. The increase in arterial-tissue cholesterol was concomitant with decreases in serum high-density (H.D.L.) and low-density (L.D.L.) lipoprotien cholesterol.
D000328:Adult; D001161:Arteriosclerosis / Q000209:etiology; D002784:Cholesterol / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007009:Hypolipoproteinemias / Q000150:complications / Q000209:etiology; D007082:Ileum / Q000601:surgery*; D007583:Jejunum / Q000601:surgery*; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D008638:Mesenteric Arteries / Q000378:metabolism*; D009765:Obesity / Q000378:metabolism* / Q000628:therapy; D011183:Postoperative Complications
D008075:Lipoproteins, HDL; D002784:Cholesterol