alpha-fetoprotein in rats treated with anti-thymocytic serum.
Serum alpha-fetoprotein was detected by immunodiffusion in rats treated with anti-thymocytic serum. Augmented synthesis of AFP is related to compensatory hyperplasia of liver cells secondary to a state of hypoproteinemia in the proteinuric nephritic animals. The nephritis was produced by the anti-basement membrane antibodies present in the thymocytic antiserum.
D000818:Animals; D000961:Antilymphocyte Serum / Q000494:pharmacology*; D004032:Diet; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology; D008099:Liver / Q000166:cytology / Q000378:metabolism; D008103:Liver Cirrhosis / Q000209:etiology; D051381:Rats; D013601:T-Lymphocytes / Q000276:immunology*; D013936:Thymidine / Q000378:metabolism; D000509:alpha-Fetoproteins / Q000378:metabolism*; D004124:p-Dimethylaminoazobenzene
D000961:Antilymphocyte Serum; D000509:alpha-Fetoproteins; D004124:p-Dimethylaminoazobenzene; D013936:Thymidine