Total support of the circulation of a patient with post-cardiotomy stone-heart syndrome by a partial artificial heart (ALVAD) for 5 days followed by heart and kidney transplantation.
A patient with acute bacterial endocarditis in whom ischaemic contracture of the left ventricle (stone-heart syndrome) developed during aortic and mitral valve replacement had an emergency implantation of an intracorporeal partial artificial heart (an abdominal left-ventricular assist device of ALVAD). This device functioned as a total artificial heart for nearly 6 days, while a donor heart for transplantation was sought. The ALVAD was then removed, and the patient received allografts of a heart and a kidney. The transplanted heart functioned well, but the patient died 15 days later from gram-negative sepsis. There was no evidence of cardiac or renal allograft rejection.
D000208:Acute Disease; D000328:Adult; D001021:Aortic Valve / Q000601:surgery; D001243:Assisted Circulation / Q000295:instrumentation*; D003286:Contracture / Q000209:etiology; D003327:Coronary Disease / Q000209:etiology / Q000628:therapy*; D004697:Endocarditis, Bacterial / Q000601:surgery; D016027:Heart Transplantation; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006354:Heart, Artificial; D006801:Humans; D007423:Intra-Aortic Balloon Pumping / Q000295:instrumentation*; D016030:Kidney Transplantation; D008297:Male; D008943:Mitral Valve / Q000601:surgery; D009119:Muscle Contraction; D009206:Myocardium / Q000473:pathology; D011183:Postoperative Complications / Q000209:etiology / Q000628:therapy*; D013577:Syndrome; D013997:Time Factors; D014184:Transplantation, Homologous