title: A case of trisomy 22 in Pongo pygmaeus.
abstract: A behaviorally and clinically abnormal female orangutan was analyzed cytologically using general banding techniques and by an alkaline silver method for staining nucleolus organizer regions. The karyotype had 49 chromosomes, including an extra chromosome 22 (49,XX + 22). No variant chromosome types or heterozygous structural rearrangements were found. Nine of the 14 large acrocentric chromosomes, Nos. 11--17, and three of the five presumptive human G-group equivalents, i.e., two of three chromosomes 22, and one chromosome from pair 23, exhibited positive silver staining of the nucleolus organizer region (NOR).
mesh_terms: D000818:Animals; D002466:Cell Nucleolus / Q000648:ultrastructure; D005260:Female; D015186:Hominidae / Q000235:genetics*; D007621:Karyotyping; D012834:Silver; D013194:Staining and Labeling; D014314:Trisomy
chemical_list: D012834:Silver