Identification of an antigen shared by mouse liver and lung.
In response to multiple injections of liver extract from Balb/c mice, DBA/1 mice produce antibodies against a component of the liver preparation which is not F-antigen, but which is able to precipitate in gel diffusion tests. This antigen is also found in extracts of Balb/c lung, but not in a variety of other organs tested. Liver extracts from all of the inbred strains studied contain the antigen, except extracts from DBA/1 mice. Furthermore, this antigen was not found in the liver or lungs of other vertebrates tested. The antigen has been designated antigen-L1.
D000818:Animals; D000917:Antibody Formation; D000941:Antigens / Q000032:analysis*; D000939:Epitopes; D007106:Immune Sera; D007114:Immunization; D005779:Immunodiffusion; D008099:Liver / Q000276:immunology*; D008168:Lung / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008811:Mice, Inbred DBA; D008815:Mice, Inbred Strains; D014020:Tissue Extracts / Q000008:administration & dosage / Q000276:immunology
D000941:Antigens; D000939:Epitopes; D007106:Immune Sera; D014020:Tissue Extracts