Characteristics of excision repair of pyrimidine dimers in eukaryotic cells as assayed with anti-dimer sera.
An antiserum that recognizes the three types of pyrimidine dimers induced by UV-light in DNA was used to monitor their removal from eukaryotic cell nuclei. Cells able to excise dimers display a similar removal pattern: a fast process completed within a few hours leaving many dimers in the DNA.
D002460:Cell Line; D002467:Cell Nucleus / Q000032:analysis; D004247:DNA / Q000528:radiation effects*; D007106:Immune Sera; D007118:Immunoassay; D007700:Kinetics; D011740:Pyrimidine Dimers; D011863:Radioimmunoassay; D014466:Ultraviolet Rays; D005719:gamma-Globulins
D007106:Immune Sera; D011740:Pyrimidine Dimers; D005719:gamma-Globulins; D004247:DNA