title: [Clinical observations and therapy of the papillomas of the mucous membrane in the otorhinolaryngology (author's transl)].
abstract: It's possible papillomas of oral, pharyngeal and laryngeal regions concerning clinical and prognostical aspects to divide under a unit principle. In addition to the criterion of juvenile/adult you must consider solitary or multiple appearance, as well as the macroscopical keratinization. An adequate classification under the aspect of the different malignancy on the basis of morphological and clinical examination of 30 papillomas is proposed. The group of adult, multiple and unkeratinized papillomas of the larynx shows in opposite of opinions of today a tendency of malignancy. Infusion therapy with Bleomycin leads to a volume reduction and to a prolongation of the interval on the papillomas of the larynx, who tend to a malignant degeneration and to a short interval.
mesh_terms: D001761:Bleomycin / Q000627:therapeutic use; D004798:Enzymes / Q000032:analysis; D006651:Histocytochemistry; D006801:Humans; D007822:Laryngeal Neoplasms / Q000032:analysis / Q000175:diagnosis*; D009062:Mouth Neoplasms / Q000032:analysis / Q000175:diagnosis*; D010212:Papilloma / Q000032:analysis / Q000175:diagnosis* / Q000188:drug therapy; D010610:Pharyngeal Neoplasms / Q000032:analysis / Q000175:diagnosis*; D011379:Prognosis
chemical_list: D004798:Enzymes; D001761:Bleomycin
vernacular_title: Klinik und Therapie von Schleimhautpapillomen im HNO-Bereich.