Chloramphenicol binding to normal and kwashiorkor sera.
The binding of chloramphenicol to normal and kwashiorkor sera was investigated in vitro. Chloramphenicol is predominantly albumin bound, although a significant degree of binding to the other major protein fractions occurs. From the clinical view point, a decreased degree of binding of kwashiorkor serum (+/-5%) is not of significance.
D000510:Alpha-Globulins / Q000378:metabolism; D001609:Beta-Globulins / Q000378:metabolism; D002648:Child; D002701:Chloramphenicol / Q000378:metabolism*; D006801:Humans; D007732:Kwashiorkor / Q000097:blood*; D011485:Protein Binding; D012709:Serum Albumin / Q000378:metabolism; D013019:South Africa
D000510:Alpha-Globulins; D001609:Beta-Globulins; D012709:Serum Albumin; D002701:Chloramphenicol