Production of 6-oxo-PGF1 alpha by human lung in vivo.
The production of 6-oxo-PGF1 alpha, a stable hydrolysis product of prostacyclin (PGI2), by human lung was demonstrated in five adults. The lowest increase in 6-oxo-PGF1 alpha on passage through the lung was noted in a woman on oral contraceptives.
D000328:Adult; D011464:Epoprostenol / Q000378:metabolism; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D008168:Lung / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011458:Prostaglandins E / Q000378:metabolism; D011651:Pulmonary Artery
D011458:Prostaglandins E; D011464:Epoprostenol