Facilitated transport of urea across the gall-bladder luminal membrane.
Counterflow experiments demonstrate the existence of urea counter-transport on the epithelium luminal surface. This phenomenon disappears when 10(-4) M phloretin is added to the perfusion fluid. Moreover counterflow experiments made using thiourea as elicitor, demonstrate that the phenomenon is specific for the urea.
D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002023:Bufo bufo; D004848:Epithelium / Q000378:metabolism; D005260:Female; D005704:Gallbladder / Q000187:drug effects / Q000378:metabolism*; D007700:Kinetics; D010693:Phloretin / Q000494:pharmacology; D013890:Thiourea / Q000494:pharmacology; D014508:Urea / Q000378:metabolism*
D014508:Urea; D013890:Thiourea; D010693:Phloretin