[Detection of antigens of endogenous viruses of the C-type during mouse development].
Embryos of the 12th-20th day of gestation, newborn and adult AKR and BALB/c mice were investigated for the presence of mouse C-type virus major structural p30 protein (gs-1) and Gross leukemia virus  type-specific antigen AGLV) by means of radioimmunodiffusion with test systems. The p30 protein was distinctly determined from the 12th day of intrauterine development in both mouse lines; it persisted in the embryo tissues until birth and was detectable also in the AKR and BALB/c mouse tissues from the first days of postnatal development and during the whole life. AGLV was not revealed in BALB/c and AKR embryos and in adult BALB/c mice; however it was found in the AKR newborn mice since the 1st-2nd day after birth. Basing on these data a conclusion was drawn that p30 protein and AGLV were expressed independently according to the radioimmuno-diffusion method sensitivity.
D000406:AKR murine leukemia virus; D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D000956:Antigens, Viral / Q000032:analysis*; D000939:Epitopes; D005779:Immunodiffusion; D051379:Mice; D008806:Mice, Inbred AKR / Q000196:embryology / Q000382:microbiology*; D008807:Mice, Inbred BALB C / Q000196:embryology / Q000382:microbiology*; D012190:Retroviridae; D014764:Viral Proteins / Q000032:analysis*
D000956:Antigens, Viral; D000939:Epitopes; D014764:Viral Proteins
Vyiavlenie antigenov éndogennykh virusov C-tipa v protsesse razvitiia u mysheĭ.