Influence of physiological saline, dextran 70, hydroxyethyl starch, degraded gelatin, and fat emulsion solutions on screen filtration pressure.
The effect of 0.9% NaCl solution, dextran 70, hydroxyethyl starch, degraded gelatin and fat emulsion on Hb, Hct, platelet count and screen filtration pressure has been studied in the rabbit. Dextran 70, hydroxyethyl starch and degraded gelatin caused hemodilution and decreased platelet count. Screen filtration pressure increased after infusion of degraded gelatin and tended to decrease after dextran 70 and hydroxyethyl starch. 0.9% NaCl and fat emulsion caused less pronounced changes. Intraportal infusion of 7 ml/kg body weight of the same solutions gave results which at present are difficult to interpret.
D000818:Animals; D001772:Blood Cell Count; D001794:Blood Pressure / Q000187:drug effects*; D003911:Dextrans / Q000494:pharmacology*; D004655:Emulsions; D005223:Fats / Q000494:pharmacology*; D005260:Female; D005780:Gelatin / Q000494:pharmacology*; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006895:Hydroxyethyl Starch Derivatives / Q000494:pharmacology*; D007275:Injections, Intravenous; D008297:Male; D010974:Platelet Aggregation / Q000187:drug effects*; D011817:Rabbits; D012462:Saline Solution, Hypertonic / Q000494:pharmacology*; D012965:Sodium Chloride / Q000494:pharmacology*; D013213:Starch / Q000031:analogs & derivatives*; D014462:Ultrafiltration
D003911:Dextrans; D004655:Emulsions; D005223:Fats; D006454:Hemoglobins; D006895:Hydroxyethyl Starch Derivatives; D012462:Saline Solution, Hypertonic; D012965:Sodium Chloride; D005780:Gelatin; D013213:Starch