Identification of the Gross cell surface antigen associated with murine leukemia virus-infected cells.
The Gross cell surface antigen (GCSA) is produced by cells that are either exogenously infected with murine leukemia virus (MuLV) or are expressing endogenous MuLV genomes. In immune precipitation assays, GCSA was resolved into two serologically distinct 85,000- and 95,000-dalton viral proteins. These antigenic components are glycosylated forms of the polyprotein precursors of the MuLV internal structural proteins.
D000406:AKR murine leukemia virus / Q000276:immunology*; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D006023:Glycoproteins / Q000276:immunology; D007942:Leukemia, Experimental; D051379:Mice; D008970:Molecular Weight; D011498:Protein Precursors / Q000276:immunology; D014764:Viral Proteins / Q000276:immunology
D000956:Antigens, Viral; D000939:Epitopes; D006023:Glycoproteins; D011498:Protein Precursors; D014764:Viral Proteins