[Application to the study of connections in the CNS of the retrograde axonal transport of an iron-dextran complex].
The retrograde axonal transport of an iron-dextran complex was observed in neurons of the substantia nigra and of the intralaminar nuclei of the thalamus, after previous injection into the striatum. The histochemical demonstration of iron is simple and rapid, and can be combined with that of horseradish peroxidase, under precise conditions in the sequence of reactions. The iron-dextran complex revealed to be a valuable material for neuronal connectivity studies in the central nervous system.
D000818:Animals; D001370:Axonal Transport; D001369:Axons / Q000502:physiology / Q000648:ultrastructure; D003342:Corpus Striatum / Q000502:physiology*; D003911:Dextrans / Q000378:metabolism*; D006651:Histocytochemistry; D007501:Iron / Q000378:metabolism*; D008297:Male; D009474:Neurons / Q000502:physiology / Q000648:ultrastructure; D051381:Rats; D013378:Substantia Nigra / Q000502:physiology*; D013788:Thalamus / Q000502:physiology*
D003911:Dextrans; D007501:Iron
Application à l'étude de connexions dans le SNC du transport axonal rétrograde d'un complexe dextran-fer. Exemple chez le rat.