A contribution to immunological tumour diagnostics in urology.
Fifty-four patients with malignant and other diseases of the urinary bladder and the prostate were examined for lymphocyte sensitization by means of electrophoretic mobility test (EM test). In this antigens from brain tissue (EF) and from malignomas of kidney, urinary bladder and prostate were used. Positive HEP values were obtained in 40 patients out of 42 with malignant tumours and in 5 patients out of 12 with other kidney diseases. With the corresponding tumour-associated antigens (TAA) in the EM-test, the histological tumour diagnosis could be confirmed in every case. Positive findings after using EF as well as the corresponding TAA are with great probability an indication of a malignant disease.
D000230:Adenocarcinoma / Q000276:immunology; D000328:Adult; D000368:Aged; D000951:Antigens, Neoplasm; D001921:Brain / Q000276:immunology; D002464:Cell Migration Inhibition; D004586:Electrophoresis; D006801:Humans; D007674:Kidney Diseases / Q000276:immunology; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D004676:Myelin Basic Protein; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000276:immunology*; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000276:immunology*
D000951:Antigens, Neoplasm; D004676:Myelin Basic Protein