Pancuronium and histamine release.
Both d-tubocurarine and pancuronium release histamine in the skin: both have been shown to cause bronchospasm after intravenous injection. It is unlikely that skin testing with either drug will detect an individual susceptibility to bronchospasm, except as a non-specific test for atopy.
D000328:Adult; D006636:Histamine Release / Q000187:drug effects*; D006801:Humans; D007428:Intradermal Tests; D010197:Pancuronium / Q000494:pharmacology*; D012867:Skin / Q000378:metabolism; D014403:Tubocurarine / Q000494:pharmacology
D010197:Pancuronium; D014403:Tubocurarine