Dried-blood spot screening for cystic fibrosis in the newborn.
Serum-immunoreactive-trypsin (I.R.T.) was measured in children with cystic fibrosis (C.F.) and a variety of controls. In the first few months of life all C.F. children had a raised serum-I.R.T. A dried blood-spot assay for I.R.T. was established and has potential as a screening test for C.F. in the newborn.
D000941:Antigens; D001800:Blood Specimen Collection; D001801:Blood Stains; D003550:Cystic Fibrosis / Q000175:diagnosis* / Q000201:enzymology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011863:Radioimmunoassay; D014357:Trypsin / Q000097:blood* / Q000276:immunology
D000941:Antigens; D014357:Trypsin