The demonstration of subtype (D or Y)-specific determinants on the surface of the presumed hepatitis B virus.
Dane particles isolated from the sera of HBsAg/ad and HBsAg/ay carriers were reacted with monospecific antibodies to the d and y subtype-specific determinants of HBsAg/. Dane particles from HBsAg/ad expressed the d determinant on their surfaces and those from HBsAg/ay sera contained the y specificity. Both complete (DNA-P and HBcAg) and defective (HBcAg alone) Dane particles expressed the subtype-specific determinants.
D000939:Epitopes; D006511:Hepatitis B Antigens; D006515:Hepatitis B virus / Q000276:immunology*; D014765:Viral Vaccines
D000939:Epitopes; D006511:Hepatitis B Antigens; D014765:Viral Vaccines