N-acetyl-neuraminic acid (NANA) serum level in the diagnostics of preleukemic states, acute micromyeloblastic leukemias and pancytopenias.
The levels of N-acetyl-neuraminic acid were determined in patients with preleukemic states, acute micromyeloblastic leukemias and pancytopenias. A statistically significant increase of NANA was found in patients with micromyeloblastic leukemia in comparison with preleukemic states and pancytopenias. A significant rise in the NANA level was observed in preleukemic states in comparison with pancytopenia of other origins. The assay of the NANA level may be employed as a sensitive biochemical test for differential diagnostics of these diseases.
D003937:Diagnosis, Differential; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis*; D010198:Pancytopenia / Q000175:diagnosis*; D011289:Preleukemia / Q000175:diagnosis*; D012794:Sialic Acids / Q000097:blood*
D012794:Sialic Acids