Interferon therapy in myelomatosis.
Four patients with myelomatosis (one IgG-chi-type, two IgA-chi, and one Bence Jones-x) were given human leucocyte interferon as the only treatment for from 3 to 19 months. Remission was complete in two patients and partial in the other two. Normal bone-marrow haematopoiesis was slightly inhibited. The disease has not so far progressed in any of the patients.
D000368:Aged; D001536:Bence Jones Protein; D001772:Blood Cell Count; D005260:Female; D005500:Follow-Up Studies; D006410:Hematopoiesis; D006801:Humans; D007070:Immunoglobulin A; D007147:Immunoglobulin Light Chains; D007372:Interferons / Q000627:therapeutic use*; D008297:Male; D009101:Multiple Myeloma / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D012075:Remission, Spontaneous
D007070:Immunoglobulin A; D007147:Immunoglobulin Light Chains; D001536:Bence Jones Protein; D007372:Interferons