Prophylactic treatment of alcoholism by lithium carbonate. A controlled study.
Lithium therapy has been shown to have a therapeutic influence in reducing the drinking and incapacity by alcohol in depressive alcoholics in a prospective double-blind placebo-controlled trial conducted over one year, but it had no significant effect on non-depressed patients. Patients in the trial treated by placebo had significantly greater alcoholic morbidity if they were depressive than if they were non-depressive.
D000328:Adult; D000428:Alcohol Drinking; D000437:Alcoholism / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D003863:Depression / Q000139:chemically induced / Q000517:prevention & control*; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010919:Placebos
D010919:Placebos; D008094:Lithium