The Lewis system: New histocompatibility antigens in renal transplantation.
Lewis antigen types (Le, le) were retrospectively determined in 255 first-kidney-transplant recipients. Actuarial survival of grafts at two years was significantly lower in the le/le recipients than in the Le recipients. This indicates that mismatching of these antigens contributes to rejection of kidney transplants. The effects of mismatching for the Lewis and HLA antigen systems seemed to be additive.
D000939:Epitopes; D006085:Graft Survival; D006680:HLA Antigens / Q000032:analysis*; D006650:Histocompatibility Testing; D006801:Humans; D007668:Kidney / Q000276:immunology; D016030:Kidney Transplantation; D007983:Lewis Blood Group Antigens; D012189:Retrospective Studies; D014184:Transplantation, Homologous
D000939:Epitopes; D006680:HLA Antigens; D007983:Lewis Blood Group Antigens