Clinico-laboratory aspects of anti-nuclear and anti-native DNA antibody tests.
Available techniques for detection of anti-nuclear antibodies are here briefly reviewed. The relatively insensitive LE cell test has been largely supplanted by the indirect immunofluorescent ANA test which should be reported in terms of titre and pattern. Specific measurement of nDNA antibodies is now a regular technique in SLE diagnosis and management.
D000974:Antibodies, Antinuclear / Q000032:analysis*; D001323:Autoantibodies / Q000032:analysis*; D003095:Collagen Diseases / Q000175:diagnosis*; D004247:DNA / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis; D009504:Neutrophils
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D004247:DNA