title: Cellular content of amniotic fluid as predictor of central nervous system malformations.
abstract: Prospective observations on 442 consecutive samples have confirmed that pregnancies with CNS malformations are regularly associated with an abnormal cellular content of amniotic fluid. A crude semiquantitative test of the cell content can give valuable clinical information in relation to borderline amniotic fluid alpha-fetoprotein values, and help to detect false positive AFP's.
mesh_terms: D000649:Amniocentesis; D000653:Amniotic Fluid / Q000166:cytology* / Q000378:metabolism; D002490:Central Nervous System / Q000002:abnormalities*; D005260:Female; D006801:Humans; D008264:Macrophages / Q000473:pathology; D011247:Pregnancy; D000509:alpha-Fetoproteins / Q000378:metabolism
chemical_list: D000509:alpha-Fetoproteins