Immune responses to some proteins and synthetic polypeptides in inbred strains of rats.
The antibody responses to DNP-bovine gamma globulin, bovine gamma globulin, human serum albumin, ovalbumin, pepsin and five synthetic polypeptides were examined in strains of inbred rats representative of eight common major histocompatibility complex (RTI) haplotypes. With each antigen the antibody response varied considerably among strains, and the data provide many potential strain and antigen combinations with which to study the genetic control of the immune response.
D000818:Animals; D000917:Antibody Formation; D002417:Cattle; D004136:Dinitrobenzenes / Q000276:immunology; D004306:Dose-Response Relationship, Immunologic; D005260:Female; D006801:Humans; D008297:Male; D010047:Ovalbumin / Q000276:immunology; D010434:Pepsin A / Q000276:immunology; D010455:Peptides / Q000276:immunology*; D051381:Rats; D011912:Rats, Inbred ACI; D011914:Rats, Inbred BN; D011916:Rats, Inbred F344; D011917:Rats, Inbred Lew; D011920:Rats, Inbred WF; D012709:Serum Albumin / Q000276:immunology; D005719:gamma-Globulins / Q000276:immunology
D004136:Dinitrobenzenes; D010455:Peptides; D012709:Serum Albumin; D005719:gamma-Globulins; D010047:Ovalbumin; D010434:Pepsin A