title: Repeated failure of nickel-containing prosthetic heart valves in a patient allergic to nickel.
abstract: Life-threatening peri-prosthetic incompetence developed with two successive nickel-containing mitral-valve prostheses in a patient allergic to nickel. Neither prosthesis had been incorporated satisfactorily. Her present nickel-free prosthesis seems to be satisfactory 22 months after insertion. Since allergy to nickel may have been involved in the failure of these prostheses, it is recommended that nickel-sensitive patients should be given nickel-free prostheses.
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000209:etiology*; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000209:etiology*; D008946:Mitral Valve Stenosis / Q000601:surgery; D009532:Nickel / Q000009:adverse effects*; D011183:Postoperative Complications / Q000209:etiology*; D012008:Recurrence; D013997:Time Factors
chemical_list: D009532:Nickel