Endogenous type C RNA virus of Odocoileus hemionus, a mammalian species of New World origin.
Type C RNA viruses have been isolated from several Old World vertebrates, and an even larger number of Old World species have been shown to contain endogenous viral genetic sequences. The present report describes the first isolation of type C virus endogenous to a species originating in the New World. This virus, isolated from cells of the Columbian black-tailed deer, Odocoileus hemionus, is shown to possess genetic sequences in common with DNA of its species of origin. While it shares biochemical and immunologic characteristics with other mammalian type C viruses, its immunologic properties readily distinguish it from known endogenous viruses.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001483:Base Sequence; D002460:Cell Line; D004247:DNA / Q000032:analysis; D004279:DNA, Viral / Q000032:analysis; D003670:Deer / Q000382:microbiology*; D004790:Enzyme Induction; D008274:Magnesium / Q000494:pharmacology; D008345:Manganese / Q000494:pharmacology; D009693:Nucleic Acid Hybridization; D012194:RNA-Directed DNA Polymerase / Q000096:biosynthesis / Q000378:metabolism; D012190:Retroviridae / Q000201:enzymology / Q000276:immunology / Q000302:isolation & purification*
D000956:Antigens, Viral; D004279:DNA, Viral; D008345:Manganese; D004247:DNA; D012194:RNA-Directed DNA Polymerase; D008274:Magnesium