[Therapeutic effect of myelin basic protein and synthetic encephalitogenic peptide in guinea pigs with experimental allergic encephalomyelitis].
Effect of antigenic factors of experimental allergic encephalomyelitis (alkaline protein of myelin and synthetic encephalitogenic peptide) was studied in guinea pigs with distinct manifestations of the experimental allergic encephalomyelitis. The animals recovered after prolonged administration of alkaline protein of myelin within 14 days, if they were sensibilized either by bovine alkaline protein of myelin or by synthetic encephalitogenic peptide. Synthetic encephalitogenic peptide was only effective in treatment of the disease caused by the peptide.
D000818:Animals; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000188:drug therapy*; D006168:Guinea Pigs; D004676:Myelin Basic Protein / Q000627:therapeutic use*; D009185:Myelin Proteins / Q000627:therapeutic use*
D004676:Myelin Basic Protein; D009185:Myelin Proteins
Izuchenie lechebnogo deĭstviia osnovnogo belka mielina i sinteticheskogo éntsefalitogennogo peptida u morskikh svinok s éksperimental'nym allergicheskim éntsefalomielitom.