title: Demonstration of the heterogeneity of the mast cell population on the basis of the mucopolysaccharide content.
abstract: From the aspect of its mucopolysaccharide content the mast cell population is not homogeneous. The pulmonary and heart muscle mast cells of the rat are alcian blue positive, the mast cells of the thyroid gland, lymph nodes, subcutaneous connective tissue, mesentery and peripheral nerve are safranin positive, whereas among the mast cells of the peritoneal cavity and the thymus there are both alcian blue and saffranin positive forms. The least acid mucopolysaccharides are in the mast cells of the peritoneal fluid, the mesentery and the lungs, whereas the most acid ones are in the mast cells of the lymph nodes, the subcutaneous connective tissue and the thyroid gland. There is a considerable difference between the two last mentioned organs. The mast cells of the subcutaneous connective tissue are end-product cells without amine or precursor turnover, whereas the mast cells of the thyroid gland incorporate and deliver amines, which may participate in the regulation of the host gland.
mesh_terms: D000423:Alcian Blue; D000818:Animals; D006025:Glycosaminoglycans / Q000032:analysis*; D008297:Male; D008407:Mast Cells / Q000032:analysis*; D051381:Rats; D013194:Staining and Labeling; D013961:Thyroid Gland / Q000032:analysis
chemical_list: D006025:Glycosaminoglycans; D000423:Alcian Blue