title: [Severe acute pancreatitis; course and response to intensive therapy (author's transl)].
abstract: Two cases of severe pancreatitis and deep shock are reviewed. In the first case measures to relieve the shock state were unsuccessful. Laparatomy was, therefore, performed and revealed acute haemorrhagic pancreatitis with diffuse purulent peritonitis. After insertion of a drain and irrigation of the abdominal cavity the incision was closed. Twice-daily lavage of the pancreatic fistula via a drain was continued until, after 5 months, the fistula healed spontaneously. In the second case intensive therapy succeeded after 9 days in controlling the acute stage of the disease. Conservative treatment was continued for 6 weeks and the patient was then discharged from hospital. He was re-admitted 3 weeks later because of suspicious clinical and biochemical signs of obstructive jaundice. Laparatomy disclosed inflammatory stenosis of the distal portion of the common bile duct and Vater's papilla and also a pancreatic pseudocyst the size of a child's head. The latter was removed and a drain was inserted. There were no postoperative complications.
mesh_terms: D000138:Acidosis / Q000209:etiology; D000208:Acute Disease; D048909:Diabetes Complications; D004298:Dopamine / Q000627:therapeutic use; D004322:Drainage; D005756:Gastritis / Q000209:etiology; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000601:surgery / Q000628:therapy*; D010288:Parenteral Nutrition; D010538:Peritonitis / Q000209:etiology; D011188:Potassium / Q000652:urine; D012121:Respiration, Artificial; D012769:Shock / Q000209:etiology; D012964:Sodium / Q000652:urine; D005719:gamma-Globulins / Q000627:therapeutic use
chemical_list: D005719:gamma-Globulins; D006493:Heparin; D012964:Sodium; D011188:Potassium; D004298:Dopamine
vernacular_title: Verlaufsbeobachtung und Intensivtherapie der schweren akuten Pankreatitis.