The inhibitory effect of methyl palmitate on heteroagglutinin formation in rats.
In Wistar rats the immunosuppressive effect of methyl palmitate on the formation of heteroagglutinins against human O-group erythrocytes was followed. An i.v. injection of methyl palmitate both delayed the heteroagglutinin formation and decreased its intensity. The inhibitory effect of methyl palmitate was not accompained by the subsequent hyperactive phase as could be observed in the previous experiments using ethyl palmitate.
D000017:ABO Blood-Group System; D000818:Animals; D000910:Antibodies, Heterophile; D000917:Antibody Formation / Q000187:drug effects*; D000941:Antigens; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D007165:Immunosuppression Therapy; D010168:Palmitates / Q000494:pharmacology*; D010169:Palmitic Acids / Q000494:pharmacology*; D051381:Rats
D000017:ABO Blood-Group System; D000910:Antibodies, Heterophile; D000941:Antigens; D010168:Palmitates; D010169:Palmitic Acids