Evaluation of macrophage electrophoretic mobility (MEM) test as an indicator of cellular immunity in ocular tumours.
The macrophage electrophoretic mobility (MEM) test of Field and Caspary did not clearly separate patients with ocular neoplastic disease from those with inflammatory disease, although there was some indication of discrimination between choroidal melanoma and ocular inflammation. In our hands the test failed to give a reproducible result for the immunodiagnosis of ocular malignancy. The technique, however, seems to provide some indication of delayed hypersensitivity in experimental inflammatory eye diseases when relatively pure antigens are used.
D000818:Animals; D000941:Antigens; D002464:Cell Migration Inhibition; D004586:Electrophoresis; D005134:Eye Neoplasms / Q000276:immunology*; D006168:Guinea Pigs / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D066298:In Vitro Techniques; D008264:Macrophages / Q000276:immunology*; D004676:Myelin Basic Protein / Q000276:immunology; D012160:Retina / Q000276:immunology; D013997:Time Factors; D014373:Tuberculin / Q000276:immunology
D000941:Antigens; D004676:Myelin Basic Protein; D014373:Tuberculin