[Study of the effect of the sera of patients with rheumatism on the blast transformation in the mixed lymphocyte culture].
The authors studied the influence of the blood sera of 23 patients suffering from rheumatism on blast-transformation of lymphocytes obtained from healthy persons, in mixed cultures: 4 sera stimulated it, 5--depressed, and 14 produced no effect. Among patients whose sera depressed the blast-transformation persons with a more severe cardiovascular insufficiency prevailed. The content of IgG, IgM and alpha2-globulins in these sera was greater.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000510:Alpha-Globulins; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents; D066298:In Vitro Techniques; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D008875:Middle Aged; D012213:Rheumatic Fever / Q000097:blood / Q000276:immunology*
D000510:Alpha-Globulins; D007166:Immunosuppressive Agents
Izuchenie vliianiia syvorotok bol'nykh revmatizmom na blasttransformatsiiu v smeshannoĭ kul'ture limfotsitov.