Motor innervation of the urinary tract studied by retrograde axonal transport of protein.
A new method for tracing the nervous control of the bladder is described. A protein substance, horseradish peroxidase, has been shown to be absorbed and transported by nerve fibers. The substance was injected into the bladder neck region of a series of dogs. After uptake by motor neurons the horseradish was carried to the spinal cord segment controlling micturition. Implications regarding the neurophysiology of the urinary tract are discussed.
D000818:Animals; D001370:Axonal Transport; D004285:Dogs; D005725:Ganglia, Autonomic / Q000166:cytology*; D006735:Horseradish Peroxidase; D007001:Hypogastric Plexus / Q000166:cytology; D008297:Male; D009046:Motor Neurons / Q000166:cytology*; D010544:Peroxidases; D013116:Spinal Cord / Q000166:cytology*; D014521:Urethra / Q000294:innervation; D001743:Urinary Bladder / Q000294:innervation*; D014554:Urination
D006735:Horseradish Peroxidase; D010544:Peroxidases