Amniotic fluid total proteins, electrophoretic patterns, total amino acids and creatinine in diabetic women.
Total proteins, total-acids, creatinine and the five major protein-fractions were determined in amniotic fluid of 9 diabetic mothers and 42 normal women. The mean value of the estimated patterns in the diabetic subgroup of living full-term infants was within normal, except a significant decrease in creatinine, albumin and gamma-globulin. A highly significant decrease in albumin, gamma-globulin and total amino acids in the amniotic fluid of those given stillbirth infants (SB), while a significant increase was found in both of total proteins and albumin in cases developed respiratory distress syndrome (RDS). In addition to a significant increase in creatinine, alpha 1-, alpha 2- and beta-globulins in both subgroups of SB and RDS. The A/G ratio of the 3 subgroups were significantly decreased especially those of SB.
D000328:Adult; D000596:Amino Acids / Q000378:metabolism*; D000653:Amniotic Fluid / Q000378:metabolism*; D003404:Creatinine / Q000378:metabolism*; D004587:Electrophoresis, Agar Gel / Q000379:methods; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*; D005719:gamma-Globulins / Q000378:metabolism
D000596:Amino Acids; D011506:Proteins; D005719:gamma-Globulins; D003404:Creatinine