Chemotherapy in testicular tumors.
Surprisingly good clinical results are obtained by means of the so-called synchronized treatment with vincristine or bleomycin or adriamycin combined with Ifosfamid when cell-kinetic conditioning factors are taken into consideration. The results could neither be obtained with monotherapy nor by the aid of various combined therapies. Of 22 patients affected by metastasizing malignant testicular tumors a complete remission could be achieved in 14 continuing up to a period of 18 months. Six patients died. The answer to what extent these therapeutic results will be confirmed over a longer observation period, has, however, to be put off until a later date.
D001761:Bleomycin / Q000627:therapeutic use; D002369:Castration; D002455:Cell Division; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D006801:Humans; D007069:Ifosfamide / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000188:drug therapy; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D009362:Neoplasm Metastasis; D012187:Retroperitoneal Space / Q000601:surgery; D013724:Teratoma / Q000188:drug therapy; D013736:Testicular Neoplasms / Q000188:drug therapy*; D014750:Vincristine / Q000627:therapeutic use
D001761:Bleomycin; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D007069:Ifosfamide