Particles resembling oncornaviruses. Spontaneous release from cultured meningioma cells.
A cell culture from thoracic cord meningioma tissue obtained at surgery was maintained for several passages in cell culture. These cells spontaneously released particles with an RNA of high-molecular weight (90S to 95S) and a density similar to that of type C oncornaviruses. The implications of these results and similar findings by others are discussed.
D000293:Adolescent; D002478:Cells, Cultured; D006801:Humans; D008297:Male; D008579:Meningioma / Q000382:microbiology*; D009858:Oncogenic Viruses / Q000201:enzymology / Q000302:isolation & purification*; D012367:RNA, Viral / Q000032:analysis; D012194:RNA-Directed DNA Polymerase / Q000032:analysis; D013120:Spinal Cord Neoplasms / Q000382:microbiology*
D012367:RNA, Viral; D012194:RNA-Directed DNA Polymerase