A tumor T cell line which can be specifically activated by antigen.
We have shown that permanently transformed T cells of a leukemic line (485-2) maintain their immunocompetent function and can be specifically activated by antigen. This cell line should facilitate investigations into the biochemical mechanisms of T cell activation and may help elucidate the nature of the T cell receptor.
D000818:Animals; D000941:Antigens / Q000276:immunology*; D002460:Cell Line; D000939:Epitopes; D004912:Erythrocytes / Q000276:immunology; D006462:Hemolytic Plaque Technique; D006736:Horses; D007942:Leukemia, Experimental / Q000276:immunology*; D051379:Mice; D012756:Sheep
D000941:Antigens; D000939:Epitopes