Neo-enactin, a new antifungal antibiotic potentiating polyene antifungal antibiotics. II. Taxonomic studies of the producing microorganism and simultaneous production of bleomycin group and streptothricin-like antibiotics.
A new antifungal antibiotic, named neo-enactin, was produced mainly in the mycelia of strain H 829-MY 10. Strain H 829-MY 10 was identified as a Streptoverticillium, determined to be nonchromogenic, and fits in the white color-series. Although Streptoverticillium olivoreticuli is known to be chromogenic, strain H 829-MY 10 is most related to that species. Thus, strain H 829-MY 10 is named as Streptoverticillium olivoreticuli subsp. neoenacticus. Besides neo-enactin, two bleomycin-group antibiotics and two streptothricin-like antibiotics were simultaneously produced by strain H 829-MY 10.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D000935:Antifungal Agents / Q000096:biosynthesis*; D001761:Bleomycin / Q000096:biosynthesis*; D004357:Drug Synergism; D006877:Hydroxamic Acids; D011090:Polyenes; D013302:Streptomyces / Q000145:classification* / Q000378:metabolism; D013309:Streptothricins / Q000096:biosynthesis*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D006877:Hydroxamic Acids; D011090:Polyenes; D001761:Bleomycin; D013309:Streptothricins; C019022:neo-enactin