title: The physiochemical and immunological characterization of Gm (1) antibodies from normal human serum.
abstract: The mol. wt and charge characteristics of Gm(1) antibodies from normal human serum were studied by gel filtration and DEAE- anion exchange chromatography. The effect on anti-Gm(1) activity, of incubating individual antisera with disulphide reducing agents, and with anti-IgG or anti-IgM immunoabsorbents were also studied. The results demonstrate the existence of a low molecular weight IgM protein with anti-Gm(1) activity.
mesh_terms: D000906:Antibodies; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D004229:Dithiothreitol / Q000494:pharmacology; D000939:Epitopes; D006386:Hemagglutination Tests; D006801:Humans; D007126:Immunoglobulin Allotypes; D007141:Immunoglobulin Fc Fragments; D007143:Immunoglobulin Heavy Chains; D007075:Immunoglobulin M; D008623:Mercaptoethanol / Q000494:pharmacology; D008970:Molecular Weight
chemical_list: D000906:Antibodies; D000939:Epitopes; D007126:Immunoglobulin Allotypes; D007141:Immunoglobulin Fc Fragments; D007143:Immunoglobulin Heavy Chains; D007075:Immunoglobulin M; D008623:Mercaptoethanol; D004229:Dithiothreitol