title: Urinary beta 2 microglobulin in upper and lower urinary-tract infections.
abstract: Beta 2-- microglobulin excretion in 24 h urine collections and beta2- microglobulin clearance were significantly increased in patients with upper-urinary-tract infections, but beta 2- microglobulin clearance and excretion were normal in patients with cystitis. Beta 2-microglobulin estimation may be used to distinguish between upper and lower urinary-tract infections, except when pre-existing tubular damage is present. Voided urine must have a pH above 6 . 0, since beta 2- microglobulin is rapidly degraded in the bladder at low pH.
mesh_terms: D000368:Aged; D001609:Beta-Globulins / Q000652:urine*; D002940:Circadian Rhythm; D003404:Creatinine / Q000652:urine; D003556:Cystitis / Q000652:urine; D004927:Escherichia coli Infections / Q000652:urine; D005921:Glomerulonephritis / Q000652:urine; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008875:Middle Aged; D011507:Proteinuria / Q000652:urine; D011512:Proteus Infections / Q000652:urine; D011513:Proteus mirabilis; D011552:Pseudomonas Infections / Q000652:urine; D011550:Pseudomonas aeruginosa; D014552:Urinary Tract Infections / Q000652:urine*; D001613:beta 2-Microglobulin / Q000652:urine*
chemical_list: D001609:Beta-Globulins; D001613:beta 2-Microglobulin; D003404:Creatinine