B lymphocyte alloantigen specificities present on cultured lymphoblastoid cell lines.
Thirty-three of 34 cultured human lymphoblastoid B cell lines have been shown to express four out of five polymorphic non-HLA specificities expressed by normal B lymphocytes. The specificities were detected by 32 alloantisera produced by absorption with pooled platelets to remove HLA activity and selected from over 400 pregnancy sera. One B group (B2) which was expressed by 23% of a panel of normal B lymphocytes was not found on any of the cultured lines tested. Four T cell lines tested and myeloid line (K562) did not react with any of the B cell alloantisera.
D001402:B-Lymphocytes / Q000276:immunology*; D002460:Cell Line; D000939:Epitopes; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D007519:Isoantigens / Q000032:analysis; D011247:Pregnancy
D000939:Epitopes; D006680:HLA Antigens; D007519:Isoantigens