Cholinesterase activity in the microfilaria of Wuchereria bancrofti Cobbold.
The distribution of cholinesterase activity in the microfilaria of the nocturnally periodic Wuchereria bancrofti has been described. Using histochemical methods, cholinesterase activity has been demonstrated in the amphids (Mundgebilde), phasmids (Schwanzgebilde), nerve-ring, excretory and anal vesicles of the microfilaria. It has been found that the enzyme activity disappeared completely after treatment with the specific cholinesterase inhibitor eserine. Evidence is presented that the greater amount of the cholinesterase activity detected is related to acetylcholinesterase and the functional significance of the enzyme in the enzyme reactive structures is discussed.
D000110:Acetylcholinesterase / Q000378:metabolism; D002802:Cholinesterases / Q000378:metabolism*; D002940:Circadian Rhythm; D006801:Humans; D007988:Liberia; D008842:Microfilariae; D013194:Staining and Labeling; D014957:Wuchereria / Q000166:cytology / Q000201:enzymology*
D000110:Acetylcholinesterase; D002802:Cholinesterases