title: Prospective study of the treatment of septic shock.
abstract: A study of 113 patients with septic shock admitted to an intensive therapy unit (I.T.U.) during a 3-year period showed that a significant reduction in mortality was achieved after the introduction of a treatment programme which included early intermittent positive-pressure ventilation and aggressive surgery in addition to conventional management with fluids, oxygen, and antibiotics. Vasoactive drugs played an important but not essential role in therapy.
mesh_terms: D000328:Adult; D000368:Aged; D001442:Bacteroides Infections / Q000150:complications; D001803:Blood Transfusion; D004573:Electrolytes / Q000627:therapeutic use; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D007384:Intermittent Positive-Pressure Breathing; D008034:Lincomycin / Q000627:therapeutic use; D008875:Middle Aged; D010102:Oxygen Inhalation Therapy; D011446:Prospective Studies; D011512:Proteus Infections / Q000150:complications; D012772:Shock, Septic / Q000401:mortality / Q000628:therapy*; D013290:Streptococcal Infections / Q000150:complications; D013297:Streptococcus pyogenes; D013530:Surgical Wound Infection / Q000150:complications
chemical_list: D004573:Electrolytes; D005839:Gentamicins; D008034:Lincomycin