title: Matching for DLA-A, DLA-B and DLA-D antigens and skin allograft survival in unrelated beagle dogs.
abstract: The effect of matching for immunogenetic markers on the survival of skin allografts in unrelated dogs has been studied. Skin grafts in recipients differing from donors for either DLA-A or DLA-B antigens, or both, had mean survival times (MST) of 9.3, 9.7 and 8.5 days, respectively. Differences between these groups were not significant. Prolonged survival of skin grafts, however, was found in SK-LD-indentical (MST: 12.4 days) or SD-identical/LD-different (MST: 12.5 days) donor-recipient combinations. We conclude that dkin allograft survival in dogs appears to be controlled by DLA-A and DLA-B, but not by DLA-D determinants.
mesh_terms: D000818:Animals; D004285:Dogs / Q000276:immunology*; D000939:Epitopes; D006085:Graft Survival; D006649:Histocompatibility Antigens; D006650:Histocompatibility Testing; D016038:Skin Transplantation; D014184:Transplantation, Homologous
chemical_list: D000939:Epitopes; D006649:Histocompatibility Antigens