[Joint therapy of experimental tumors with diazan in combination with antibiotics].
Antitumor efficiency of combined therapy of experimental tumors with diazan and antibiotics was studied. The experiments were performed with leukosis La and P-388 and Walker carcinosarcoma. The kinetic regularities of the tumor process were used in planning regimens of the combined therapy. It was found that the combined use of diazan with antitumor antibiotics of the anthracyclin series increased the therapy efficacy. Therapeutic synergism of the drugs was noted which was evident from a significant increase in the average life rate and recovery of a part of the animals.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001391:Azo Compounds / Q000008:administration & dosage*; D001761:Bleomycin / Q000008:administration & dosage; D002279:Carcinoma 256, Walker / Q000188:drug therapy; D002360:Carubicin / Q000008:administration & dosage; D003630:Daunorubicin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D007942:Leukemia, Experimental / Q000188:drug therapy; D051379:Mice; D008810:Mice, Inbred C57BL; D009374:Neoplasms, Experimental / Q000188:drug therapy*; D051381:Rats; D013386:Succinates / Q000008:administration & dosage
D000903:Antibiotics, Antineoplastic; D000970:Antineoplastic Agents; D001391:Azo Compounds; D013386:Succinates; D001761:Bleomycin; D004317:Doxorubicin; D002360:Carubicin; D003630:Daunorubicin
Kombinirovannaia terapiia éksperimental'nykh opukholeĭ v sochetanii s antibiotikami.