title: [Bleomycin in the intratumoral treatment of advanced squamous cell carcinomas in the oto-rhino-laryngological region (author's transl)].
abstract: In 16 patients with advanced squamous cell carcinomas infiltration therapy with Bleomycin was used either peritumorally or intratumorally. In no case a chirurgical or radiological therapy could be used. The applied doses varied between 120 mg and 555 mg. With this cytostatic infiltration therapy a measurable reduction of the tumor could be achieved in all patients, in 2 patients a total and in 3 patients a partial remission could be observed. The general conditions, as well as the intake of food were improved. A further advantage was the relief of pain with this therapy.
mesh_terms: D001761:Bleomycin / Q000008:administration & dosage / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy*; D004428:Ear Neoplasms / Q000188:drug therapy*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000188:drug therapy*; D008722:Methods; D009669:Nose Neoplasms / Q000188:drug therapy
chemical_list: D001761:Bleomycin
vernacular_title: Intratumorale Bleomycin-Infiltrationstherapie bei Plattenepitheltumoren im HNO-Bereich.