title: Formation of multinucleated giant cells from circulating blood cells cultivated in diffusion chambers.
abstract: Autologous circulating rabbit blood cells have been cultivated in Millipore diffusion chambers implanted intraperitoneally for 13 days. During this period multinucleated giant cells were formed within the diffusion chambers, confirming a hematogenous origin of these cells. The diffusion chamber technique might be helpful for the investigations of factors initiating the formation of multinucleated giant cells.
mesh_terms: D000818:Animals; D001773:Blood Cells; D002454:Cell Differentiation; D002467:Cell Nucleus; D002478:Cells, Cultured; D004058:Diffusion; D011817:Rabbits