Prevention of wound infection in abdominal operations by peroperative antibiotics or povidone-iodine. A controlled trial.
The wound-infection rate after abdominal operations was compared in 113 patients randomly allocated to an untreated control group, a group receiving preoperative lincomycin and tobramycin, or a group receiving local instillation of povidone-iodine. The wound-infection rate was 8.1% in 37 patients receiving antibiotics, 42.1% in 38 untreated controls, and 39.5% in 38 patients in the povidone-iodine group.
D000005:Abdomen / Q000601:surgery*; D000336:Aerosols; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D006801:Humans; D007273:Injections, Intramuscular; D008034:Lincomycin / Q000008:administration & dosage* / Q000627:therapeutic use; D011182:Postoperative Care; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000008:administration & dosage* / Q000627:therapeutic use; D011300:Preoperative Care; D013530:Surgical Wound Infection / Q000517:prevention & control*; D014031:Tobramycin / Q000008:administration & dosage* / Q000627:therapeutic use
D000336:Aerosols; D000900:Anti-Bacterial Agents; D011206:Povidone-Iodine; D008034:Lincomycin; D011205:Povidone; D014031:Tobramycin