Drug risks in pregnancy revisited.
In the important interface of assuring safe care for the pregnant mother and her developing child that falls to the family physician, current knowledge of drug risks in pregnancy is essential. A recent survey showed that an average of 4.5 drugs are taken throughout the pregnancy. Eighty percent are self-prescribed, and a positive correlation was shown between the incidence of congenital anomalies and drug intake. Numerous recent reports of previously unrecognized fetal complications of commonly prescribed and self-used drugs and heightened public awareness makes it imperative that family physicians know the risk principles of major drug groups and be able to recognize drug-induced symptoms and signs in the older infant as well as in the infant.
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000033:Abortion, Threatened / Q000188:drug therapy; D000700:Analgesics / Q000009:adverse effects; D000863:Antacids / Q000009:adverse effects; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects; D000890:Anti-Infective Agents / Q000009:adverse effects; D000925:Anticoagulants / Q000009:adverse effects; D000927:Anticonvulsants / Q000009:adverse effects; D000959:Antihypertensive Agents / Q000009:adverse effects; D013956:Antithyroid Agents / Q000009:adverse effects; D003276:Contraceptives, Oral / Q000009:adverse effects; D004071:Digitalis Glycosides / Q000009:adverse effects; D004232:Diuretics / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D012739:Gonadal Steroid Hormones / Q000009:adverse effects; D006634:Histamine H1 Antagonists / Q000009:adverse effects; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D007752:Obstetric Labor, Premature / Q000188:drug therapy; D011247:Pregnancy; D019966:Substance-Related Disorders / Q000150:complications; D014149:Tranquilizing Agents / Q000009:adverse effects
D000700:Analgesics; D000863:Antacids; D000889:Anti-Arrhythmia Agents; D000890:Anti-Infective Agents; D000925:Anticoagulants; D000927:Anticonvulsants; D000959:Antihypertensive Agents; D013956:Antithyroid Agents; D003276:Contraceptives, Oral; D004071:Digitalis Glycosides; D004232:Diuretics; D012739:Gonadal Steroid Hormones; D006634:Histamine H1 Antagonists; D007004:Hypoglycemic Agents; D014149:Tranquilizing Agents