title: The effects of palmitic acid on skeletal muscle mitochondria of cold and warm acclimated rats.
abstract: The effects of palmitic acid on skeletal muscle mitochondria isolated from the hind limb muscle of cold and warm acclimated rats were studied. At higher concentrations of the fatty acid, a greater depression of both ADP/O and RCR (respiratory control ratio) was observed in the cold acclimated group. Initial ADP/O and RCC however, were higher in the cold acclimated group. The enhanced sensitivity of skeletal muscle mitochondria of the cold acclimated rat is discussed.
mesh_terms: D000064:Acclimatization; D000244:Adenosine Diphosphate / Q000378:metabolism; D000818:Animals; D003080:Cold Temperature; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology; D006358:Hot Temperature; D008297:Male; D008931:Mitochondria, Muscle / Q000187:drug effects / Q000378:metabolism*; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D010101:Oxygen Consumption / Q000187:drug effects*; D010169:Palmitic Acids / Q000494:pharmacology*; D051381:Rats
chemical_list: D005231:Fatty Acids, Unsaturated; D010169:Palmitic Acids; D000244:Adenosine Diphosphate