[Heterogeneity of L-valine pool in Actinomyces sp. 26-115 producing actinomycin C].
Free intracellular valine in Actinomyces sp. 26-115 producing actinomycin C its functionally heterogenous. There are at least 2 pools of free valine. One of them supplies valine for protein biosynthesis and the second for the antibiotic biosynthesis. The volume of the pools is estimated. Inadequate reaction of the pools to similar effects is indicative of differences in their properties. The pool participating in protein biosynthesis strives for preservation of its volume. The pool participating in the antibiotic biosynthesis is capable of enlarging its volume to various levels depending on the change in the volume of the common intracellular pool.
D000190:Actinomyces / Q000166:cytology / Q000378:metabolism*; D002250:Carbon Radioisotopes; D002701:Chloramphenicol / Q000494:pharmacology; D046508:Culture Techniques; D003609:Dactinomycin / Q000096:biosynthesis*; D007553:Isotope Labeling; D014633:Valine / Q000378:metabolism*
D002250:Carbon Radioisotopes; D003609:Dactinomycin; D002701:Chloramphenicol; D014633:Valine
Geterogennost' pula L-valina Actinomyces sp. 28-115 produtsenta aktinomitsina C.