[Various risk factors in the precipitaiton of complications caused by anesthetics and muscle relaxants].
From this study an important notion emerges concerning the risk factors in accidents due to general anaesthetics and myorelaxants. Among these factors, three are clinical parameters which can be assessed by any anaesthetist: the presence of atopy, of a previous drug allergy, of previous, repeated general anaesthesia, close together in timel Two factors were the subject of an experimental study, routinely investigating an abnormal histamine reactivity of the skin, and a latent spasmophilia. No definite conclusion can be made from the results, bearing in mind certain criticisms of technical order and the small number of subjects investigated. However, these works merit being pursued. Thus, if all subjects are not equal when faced with the risks inherent to anaesthesia, a thorough study of individual risk factors will enable a preventive approach, utilising a premedication prescribed with mature consideration.
D000707:Anaphylaxis / Q000378:metabolism; D000777:Anesthetics / Q000009:adverse effects* / Q000145:classification; D003876:Dermatitis, Atopic / Q000150:complications; D003877:Dermatitis, Contact / Q000150:complications; D004342:Drug Hypersensitivity / Q000150:complications; D004576:Electromyography; D006636:Histamine Release; D006801:Humans; D009125:Muscle Relaxants, Central / Q000009:adverse effects*; D012306:Risk; D013746:Tetany / Q000150:complications / Q000503:physiopathology
D000777:Anesthetics; D009125:Muscle Relaxants, Central
Etude de différents facteurs de risque de déclenchement d'accidents aux anesthésiques et myorelaxants