[Clinical results with granulocyte transfusion (author's transl)].
16 adult patients with granulocytopenia and septicemia resistant to antibiotics received 42 granulocyte transfusions. The granulocytes were obtained from healthy donors with a blood cell separator by continuous flow centrifugation. Adding hydroxyethyl-starch an average of 1.8 X 10(10) leukocytes with 69% granulocytes were harvested in 3.5 hours. A small leukocyte increment after the transfusion was seen in half of the recipients. No correlation could be found between fever lysis and survival of the infection, which occurred in half of the cases too. A granulocyte transfusion is indicated in patients, who have granulocytopenia, sepsis and no evidence of bone marrow recovery.
D000328:Adult; D000368:Aged; D001803:Blood Transfusion; D005334:Fever / Q000628:therapy; D006098:Granulocytes / Q000637:transplantation*; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives; D007938:Leukemia / Q000150:complications; D007970:Leukopenia / Q000209:etiology / Q000628:therapy; D008875:Middle Aged; D018805:Sepsis / Q000209:etiology / Q000628:therapy*
D006895:Hydroxyethyl Starch Derivatives
Klinische Ergebnisse bei der Anwendung von Granulozytentransfusionen.