[Action on human fibrinogen of anti-sera against fibrinogen dissociated chains (author's transl)].
The preparation of immune anti-sera against A alpha, B beta and gamma chains of human fibrinogen is described. Using these anti-sera, the authors have shown that the antigenic parts of the gamma chain are masked inside the molecule of fibrinogen and are not accessible on the surface of the molecule.
D000818:Animals; D000918:Antibody Specificity; D004591:Electrophoresis, Polyacrylamide Gel; D000939:Epitopes; D005340:Fibrinogen; D005344:Fibrinopeptide A; D005345:Fibrinopeptide B; D005455:Fluorescent Antibody Technique; D006386:Hemagglutination Tests; D006801:Humans; D007106:Immune Sera; D010503:Periodic Acid-Schiff Reaction; D011487:Protein Conformation; D011817:Rabbits; D012967:Sodium Dodecyl Sulfate
D000939:Epitopes; D007106:Immune Sera; D005344:Fibrinopeptide A; D005345:Fibrinopeptide B; D012967:Sodium Dodecyl Sulfate; D005340:Fibrinogen
Action sur le fibrinogène humain d'immun-sérums dirigés contre les chaînes dissociées de ce fibrinogène