Contact urticarial skin responses to cinnamaldehyde.
A patient suffering from an eczema of the right hand showed after routine patch testing an immediate urticarial reaction to cinnamaldehyde. The same reaction could be noted in three out of eight control persons. Laboratory investigations revealed cinnamaldehyde to have a histamine liberating effect, a fact not previously mentioned in reports on untoward reactions to this compound.
D000171:Acrolein / Q000031:analogs & derivatives; D000328:Adult; D000447:Aldehydes / Q000009:adverse effects*; D002934:Cinnamates / Q000009:adverse effects; D003877:Dermatitis, Contact / Q000209:etiology* / Q000276:immunology; D006636:Histamine Release; D006801:Humans; D008297:Male; D014581:Urticaria / Q000139:chemically induced* / Q000276:immunology
D000447:Aldehydes; D002934:Cinnamates; D000171:Acrolein; C012843:cinnamaldehyde