Auditory brain stem potentials with alcohol.
Auditory brain stem potentials were recorded from unrestrained rats and from cats paralyzed with Flaxedil, before and after ingestion of intoxicating dosages of alcohol. The acute effect of alcohol was a cumulative increase in the central conduction times of successive brain stem potential peaks. Statistically significant latency changes were found for peaks attributed to neural structures as far peripherally as the medulla. This depressive influence of alcohol on sensory transmission was independent of variations in stimulus intensity and body temperature.
D000161:Acoustic Stimulation; D000435:Alcoholic Intoxication / Q000503:physiopathology*; D000818:Animals; D001306:Auditory Pathways / Q000187:drug effects / Q000503:physiopathology*; D001933:Brain Stem / Q000187:drug effects / Q000503:physiopathology*; D004569:Electroencephalography; D005071:Evoked Potentials / Q000187:drug effects; D006801:Humans; D051381:Rats; D009435:Synaptic Transmission / Q000187:drug effects