A receptor-immunoassay for the determination of the specificity of anti-HCG-beta sera.
In the receptor-immunoassay, the binding of anti-HCG-beta sera to 125I-HCG and 125I-HLH is measured in the presence of bovine corpus luteum "receptor". Anti-sera specific for HCG show little binding with 125I-HLH. The receptor-immunoassay permits an evaluation of specificity, affinity and the ability of anti-HCG-beta sera to compete with the "receptor" for binding to 125I-HCG.
D001666:Binding Sites, Antibody; D006063:Chorionic Gonadotropin / Q000276:immunology*; D003429:Cross Reactions; D000939:Epitopes; D006801:Humans; D007106:Immune Sera / Q000592:standards*; D007118:Immunoassay / Q000379:methods*; D007457:Iodine Radioisotopes
D006063:Chorionic Gonadotropin; D000939:Epitopes; D007106:Immune Sera; D007457:Iodine Radioisotopes