On the mapping of PGM3, GLO and HLA.
In a combined Danish, American and Icelandic study, the odds for the orientation PGM3 :GLO:HLA-B:HLA-A versus GLO:HLA-B:HLA-A:PGM3 are estimated to be 75:1. The GLO:HLA recombination frequency is estimated at 5% for males and 12% for females. The recombination fraction for PGM3:GLO is 12--13% in males and is significantly higher in females (approximately free recombination). The findings are consistent with the large sex differences in recombination frequency between HLA and PGM3.
D000939:Epitopes; D005260:Female; D006680:HLA Antigens; D006650:Histocompatibility Testing; D006801:Humans; D008297:Male; D011995:Recombination, Genetic; D012737:Sex Factors
D000939:Epitopes; D006680:HLA Antigens