title: [Pathology of liver failure and hepatic coma (author's transl)].
abstract: Liver failure and hepatic coma present with various clinical and morphological counterparts. While fulminant viral hepatitis is the most common cause of acute liver failure, liver cirrhosis with vascular bypass most often is responsible for the hepatic coma in chronic diseases. Prognosis is mainly determined by the extent of liver cell necrosis and regeneration, provided extrahepatic complications do not cause death. Prognosis can best be judged by stereology of liver biopsies and determination of the alpha-fetoprotein.
mesh_terms: D000437:Alcoholism / Q000150:complications; D005234:Fatty Liver / Q000209:etiology; D006359:Heat Exhaustion / Q000150:complications; D006501:Hepatic Encephalopathy / Q000209:etiology / Q000473:pathology*; D006505:Hepatitis / Q000150:complications; D006509:Hepatitis B / Q000276:immunology; D006511:Hepatitis B Antigens; D006801:Humans; D007165:Immunosuppression Therapy; D008099:Liver / Q000032:analysis; D008103:Liver Cirrhosis / Q000150:complications; D008107:Liver Diseases / Q000473:pathology*; D008115:Liver Regeneration; D008930:Mitochondria, Liver; D009336:Necrosis; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D006511:Hepatitis B Antigens; D000509:alpha-Fetoproteins
vernacular_title: Leberinsuffizienz und Leberkoma - pathologisch-anatomische Substrate.