A distinctive antigen present in liver carcinomas induced by 3'-methyl-p-dimethylaminoazobenzene.
Hepatocellular carcinomas and cholangiocarcinomas induced in rat liver by the administration of 3'-methyl-p-dimethyl-aminoazobenzene (3'-Me-DAB) were found to contain a carcinoma distinctive antigen by immunofluorescence, immunoelectrophoresis and immunodiffusion. This carcinoma distinctive antigen does not appear to be alpha-fetoprotein (AFP) or the preneoplastic antigen.
D002759:Adenoma, Bile Duct / Q000139:chemically induced / Q000276:immunology*; D000818:Animals; D000912:Antibodies, Neoplasm; D000951:Antigens, Neoplasm / Q000302:isolation & purification; D006528:Carcinoma, Hepatocellular / Q000139:chemically induced / Q000276:immunology*; D000939:Epitopes; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D008113:Liver Neoplasms / Q000139:chemically induced / Q000276:immunology*; D008297:Male; D008749:Methyldimethylaminoazobenzene; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000276:immunology; D051381:Rats; D011919:Rats, Inbred Strains; D000509:alpha-Fetoproteins / Q000276:immunology; D004124:p-Dimethylaminoazobenzene / Q000031:analogs & derivatives
D000912:Antibodies, Neoplasm; D000951:Antigens, Neoplasm; D000939:Epitopes; D000509:alpha-Fetoproteins; D008749:Methyldimethylaminoazobenzene; D004124:p-Dimethylaminoazobenzene