[Inventory of oligoclonal fractions of subacute sclerosing panenephalitis cere-brospinal fluid in Africa with a specific immuneserum: first results (author's transl)].
The oligoclonal gamma-fractions in the cerebrospinal fluid (C.S.F.) from one case of subacute sclerosing panencephalitis (S.S.P.E.) have been studied by means of immunolectrophoresis. The gamma-zone consisted of IgG and free kappa and lambda chains. Besides that, a rabbit immune serum against S.S.P.E. C.S.F. has been prepared. This immune serum did reveal in the gamma-zone one additional protein which is different from IgG and normal tissue proteins. The possibility for this additionnal protein to be of myelinic origin is postulated, because of the demyelinisating nature of the lesion.
D000349:Africa; D000818:Animals; D000918:Antibody Specificity; D055598:Chemical Phenomena; D002621:Chemistry; D004586:Electrophoresis; D006041:Goats / Q000276:immunology; D006801:Humans; D007106:Immune Sera; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D011817:Rabbits / Q000276:immunology; D013344:Subacute Sclerosing Panencephalitis / Q000134:cerebrospinal fluid* / Q000276:immunology; D005719:gamma-Globulins / Q000134:cerebrospinal fluid
D007106:Immune Sera; D007074:Immunoglobulin G; D005719:gamma-Globulins
Inventaire des fractions oligoclonales du liquide cephalo-rachidien dans la panencephalite sclerosante subaique en Afrique a l'aide d'un immunserum specifique: premiers resultats