Serum-25-hydroxyvitamin-D concentrations in adolescent boys.
In March, 1976, vitamin-D status was investigated in 256 thirteen-year-old school boys of Asian, West Indian, andEuropean origin in Birmingham. Serum-25-hydroxyvitamin-D3 (25-OHD3) concentrations in 78% of the 124 Asian boys resembled those found in rickets and osteomalacia. Serum-25-OHD3 concentrations were also low in a few West Indian and European children. Dietary intake of vitamin D and exposure to sunlight were similar in each group. Serum-parathormone concentrations were increased in many children with low serum-25-OHD3. Reinvestigation in October, 1976, of a group of children whose serum-25-OHD, concentration had been less than 8 microng/l in March, 1976, showed pronounced improvement in all, but some still had concentrations which indicated a possible deficiency. It is suggested that the high frequency of vitamin-D deficiency in Asian adolescents would be much reduced if 1 mg of vitamin D3 was given orally each school term during adolescence.
D000293:Adolescent; D000469:Alkaline Phosphatase / Q000097:blood; D001208:Asia / Q000208:ethnology; D001824:Body Constitution; D002118:Calcium / Q000097:blood; D002762:Cholecalciferol / Q000627:therapeutic use; D004739:England; D005060:Europe / Q000208:ethnology; D005492:Folic Acid / Q000097:blood; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood*; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood; D010710:Phosphates / Q000097:blood; D044469:Racial Groups; D012621:Seasons; D012709:Serum Albumin / Q000032:analysis; D014805:Vitamin B 12 / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood* / Q000453:epidemiology / Q000517:prevention & control; D014900:West Indies / Q000208:ethnology
D006454:Hemoglobins; D006887:Hydroxycholecalciferols; D010281:Parathyroid Hormone; D010710:Phosphates; D012709:Serum Albumin; D002762:Cholecalciferol; D005492:Folic Acid; D000469:Alkaline Phosphatase; D014805:Vitamin B 12; D002118:Calcium