Antigenic relationship of human foamy virus to the simian foamy viruses.
A foamy virus isolated by Achong et al. from a human nasopharyngeal carcinoma was studied to determine its antigenic relationship to the eight known simiam foamy viruses (SFV). Using reciprocal cross-immunofluorescent and cross-neutralization techniques, we found the human isolate to be closely related to SFV type 6. In a seroepidemiological survey, neutralizing antibody to the human foamy virus was not detected in the sera of animal caretakers or laboratory personnel who routinely handled a wide variety of nonhuman primates. We conclude that the human isolate most probably represents a variant strain of SFV type 6.
D000818:Animals; D000956:Antigens, Viral; D003429:Cross Reactions; D000939:Epitopes; D005455:Fluorescent Antibody Technique; D000882:Haplorhini; D006801:Humans; D012190:Retroviridae / Q000276:immunology*; D013045:Species Specificity; D016092:Spumavirus / Q000276:immunology*
D000956:Antigens, Viral; D000939:Epitopes