title: Localization of human pancreatic polypeptide in an argyrophilic fourth cell type in islets of the rat pancreas.
abstract: An argyrophilic fourth cell type in the rat pancreatic islet can be differentiated from other silver-staining cells by using a modification of the Grimelius aqueous silver nitrate technique. Restaining of the tissues using fluorescent techniques with anti-HPP (Human Pancreatic Polypeptide) serum results in bright fluorescence in the fourth cell type.
mesh_terms: D000818:Animals; D005455:Fluorescent Antibody Technique; D006651:Histocytochemistry; D007515:Islets of Langerhans / Q000378:metabolism*; D010455:Peptides / Q000378:metabolism*; D051381:Rats; D012835:Silver Nitrate; D013194:Staining and Labeling
chemical_list: D010455:Peptides; D012835:Silver Nitrate