Immunological release of histamine and slow-reacting substance in domestic fowl.
Immunological release of histamine from the whole blood of the sensitized chickens was demonstrated. Compound 48/80 (a potent histamine releaser) released histamine from isolated chicken lung. The sensitizing antigens (bovine albumin or horse plasma) did not release histamine from the lung. Bovine albumin and horse plasma released slow-reacting substance of anaphylaxis only from the lungs of adult domestic fowl and not from ileum or lungs of immature chickens.
D000418:Albumins; D000818:Animals; D000941:Antigens; D002417:Cattle; D002645:Chickens / Q000276:immunology*; D006632:Histamine / Q000097:blood; D006636:Histamine Release; D006736:Horses; D007082:Ileum / Q000276:immunology; D008168:Lung / Q000276:immunology / Q000378:metabolism; D010949:Plasma; D013189:SRS-A / Q000096:biosynthesis*
D000418:Albumins; D000941:Antigens; D013189:SRS-A; D006632:Histamine