title: Prevention of postextraction bacteremia by local prophylaxis.
abstract: Four local prophylactic methods were studied in the prevention of postextraction bacteremia: 1) mouth rinsing with 1% iodine solution, postoperative bacteremia frequency 55%, 2) operative field isolation with cotton rolls and saliva ejector, bacteremia frequency 34%, 3) operative field isolation and disinfection with 10% iodine solution, bacteremia frequency 32%, 4) operative field isolation and disinfection with 0.5% chlorhexidine solution, bacteremia frequency 13%. The operative field isolation together with local disinfection with chlorhexidine was recommended for routine practice. However, when dealing with known or suspected risk group patients, a combined systemic and local prophylactic method was strongly recommended, as this was found in previous investigation to be the most effective method for reducing the frequency of bacteremia.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000985:Antisepsis / Q000379:methods*; D001207:Asepsis / Q000379:methods*; D002710:Chlorhexidine / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007455:Iodine / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes; D011183:Postoperative Complications / Q000517:prevention & control; D018805:Sepsis / Q000209:etiology / Q000517:prevention & control*; D013530:Surgical Wound Infection / Q000150:complications / Q000517:prevention & control*; D014081:Tooth Extraction
chemical_list: D009067:Mouthwashes; D007455:Iodine; D002710:Chlorhexidine