[Kinetics of the penetration of benzo(a)pyrene and benzo(k)fluoranthene into cells].
Microspectrofluorometric methods have been used to study the kinetics of the increase of fluorescence due to the intake of Benzo(k)Fluoranthène and Benzo(a)Pyrène in single living L cells. A computer program based on the methods of the least square fit has allowed the determination of the kinetic parameters. The results show that pinocytosis cannot be the unique mechanism of intake.
D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism*; D003201:Computers; D005449:Fluorenes / Q000378:metabolism*; D007700:Kinetics; D007739:L Cells / Q000378:metabolism*; D008433:Mathematics; D051379:Mice; D008954:Models, Biological; D013050:Spectrometry, Fluorescence; D013329:Structure-Activity Relationship
D001580:Benzopyrenes; D005449:Fluorenes
Etude des cinétiques de pénétration des benzo(a)pyrène et benzo(k)fluoranthène dans des cellules L.