Jaundice and breast-feeding among Alaskan Eskimo newborns.
The course, incidence, and severity of neonatal jaundice was studied in 95 Alaskan Eskimo infants. Breast-fed infants had higher bilirubin concentrations than bottle-fed babies. Both groups experienced high bilirubin levels, similar to those previously reported in Navajo and Oriental infants but greater than those observed in whites and blacks. A marked capacity to inhibit hepatic glucuronyl transferase was observed in breast-milk specimens but only partly accounted for the bilirubin differences between breast-fed and bottle-fed Eskimo infants. These data suggest that in some racial groups predisposed to neonatal jaundice, feeding practices significantly alter the course and severity of hyperbilirubinemia.
D000413:Alaska; D001663:Bilirubin / Q000097:blood; D001724:Birth Weight; D001903:Bottle Feeding; D001942:Breast Feeding; D014453:Glucuronosyltransferase / Q000037:antagonists & inhibitors; D006801:Humans; D007231:Infant, Newborn; D004930:Inuit; D007567:Jaundice, Neonatal / Q000209:etiology* / Q000235:genetics; D008895:Milk, Human; D044469:Racial Groups
D014453:Glucuronosyltransferase; D001663:Bilirubin