The effect of sublingually administered nitroglycerin on the contraction of the human gallbladder.
Nitroglycerin (0.5 mg) was administered sublingually either before (n = 10) or after (n = 10) a standard contraction meal (200 ml of cream) during oral cholecystography. In both groups the standard contraction meal caused a significant contraction of the gallbladder. Nitroglycerin had no significant dilatation effect; hence its benefit during an acute attack of pain in a patient with gallstones seems to be questionable.
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005704:Gallbladder / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects; D005996:Nitroglycerin / Q000009:adverse effects / Q000494:pharmacology*; D013997:Time Factors
D005996:Nitroglycerin