title: Alcohol dehydrogenase polymorphism in populations of Drosophila melanogaster. II. Relation between ADH activity and adult mortality.
abstract: Eight Drosophila melanogaster strains, seven homozygous for AdhF alleles and one for an Adh-null mutant, were compared for ADH activity in males and adult mortality on ethanol-supplemented food. The strains differed considerably in these qualities. A positive correlation was found between ADH activity and LD50. The relevance of this finding is discussed in relation to the differential selection acting on Adh genotypes kept on ethanol-supplemented food.
mesh_terms: D000429:Alcohol Oxidoreductases / Q000235:genetics* / Q000378:metabolism; D000818:Animals; D003470:Culture Media; D004331:Drosophila melanogaster / Q000235:genetics*; D000431:Ethanol / Q000494:pharmacology*; D007928:Lethal Dose 50; D008297:Male; D011110:Polymorphism, Genetic; D012641:Selection, Genetic; D013045:Species Specificity
chemical_list: D003470:Culture Media; D000431:Ethanol; D000429:Alcohol Oxidoreductases