The occurrence of new retinoblastomas after treatment.
New separate tumors have developed in 11% of eyes containing retinoblastoma treated primarily with external beam radiation. The tumors were primarily found in the inferior retinal periphery and averaged 1.5 disc diameters in size. All of the tumors were controlled, with photocoagulation and cryopexy being the most frequently used treatments.
D002675:Child, Preschool; D003452:Cryosurgery; D005134:Eye Neoplasms / Q000209:etiology* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D007223:Infant; D008028:Light Coagulation; D009378:Neoplasms, Multiple Primary / Q000209:etiology* / Q000601:surgery; D011882:Radiotherapy, High-Energy / Q000009:adverse effects; D012175:Retinoblastoma / Q000209:etiology* / Q000532:radiotherapy / Q000601:surgery