title: [Operon of riboflavin biosynthesis in Bacillus subtilis. XVI. Localization of the ribC-group markers on the chromosome].
abstract: Regulatory markers of ribC group were located on the chromosome of Bacillus subtilis by means of genetic transformation. Markers of this group controlling the regulation of riboflavin biosynthesis were mapped between markers of resistance to acriflavin and streptomycin (strC group). The value of cotransfer index between acriflavin-resistance markers and ribC markers was found to be 26--32%. Acriflavin inhibits the riboflavin biosynthesis. The level of inhibition depends on the genotype of riboflavin-producing strains, while the inhibition of the cell growth does not depend on it.
mesh_terms: D001412:Bacillus subtilis / Q000235:genetics* / Q000378:metabolism; D002874:Chromosome Mapping; D004352:Drug Resistance, Microbial; D005809:Genes, Regulator; D005819:Genetic Markers; D005838:Genotype; D009876:Operon; D012256:Riboflavin / Q000096:biosynthesis* / Q000235:genetics; D014170:Transformation, Genetic
chemical_list: D005819:Genetic Markers; D012256:Riboflavin
vernacular_title: Issledovanie operona biosinteza riboflavina u Bacillus subtilis. Soobshchenie XVI. Lokalizatsiia markerov gruppy ribC na khromosome.