Synthesis of new benzophenone derivatives with potential antiinflammatory activity.
2-Methoxy-, 2-hydroxy- and 2-acetoxy-5-methylbenzophenones and their 5-carboxyl derivatives were synthesized and characterized by elemental analysis and IR spectra. The results of prostaglandin synthetase inhibition are reported for some of these compounds.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis*; D001577:Benzophenones / Q000138:chemical synthesis* / Q000494:pharmacology; D016861:Cyclooxygenase Inhibitors; D051381:Rats
D000893:Anti-Inflammatory Agents; D001577:Benzophenones; D016861:Cyclooxygenase Inhibitors