title: Glycosaminoglycans of the plasma membranes of renal tubule and liver cells.
abstract: Glycosaminoglycans were isolated from plasma membranes of hepatic and renal tubule cells of guinea pig. Plasmalemma of renal tubule cells contained more total glycosaminoglycans, hyaluronic acid, chondroitin-4 sulfates and chondroitin-6 sulfates, and less dermatan sulfates and heparin sulfates than liver plasma membranes. These glycocalyx components, owing to their polyanionic properties, may have a role in the transport of water, ions, and macromolecules across the cell membrane.
mesh_terms: D000818:Animals; D002458:Cell Fractionation; D002462:Cell Membrane / Q000032:analysis* / Q000648:ultrastructure; D002809:Chondroitin Sulfates / Q000032:analysis; D003871:Dermatan Sulfate / Q000032:analysis; D006025:Glycosaminoglycans / Q000032:analysis*; D006168:Guinea Pigs; D006497:Heparan Sulfate / Q000032:analysis; D006595:Hexosamines / Q000032:analysis; D006820:Hyaluronic Acid / Q000032:analysis; D007684:Kidney Tubules / Q000032:analysis*; D008099:Liver / Q000032:analysis*; D009928:Organ Specificity; D013431:Sulfates / Q000032:analysis; D014574:Uronic Acids / Q000032:analysis
chemical_list: D002809:Chondroitin Sulfates; D003871:Dermatan Sulfate; D006025:Glycosaminoglycans; D006497:Heparan Sulfate; D006595:Hexosamines; D006820:Hyaluronic Acid; D013431:Sulfates; D014574:Uronic Acids