Total-body irradiation in advanced lymphosarcoma.
Thirty patients with stage III and IV non-Hodgkin's lymphoma were treated by total-body irradiation (TBI). Eleven patients had previously received local radiotherapy or chemotherapy. Toxicity was confined to haematological depression. Complete remission of disease was achieved in 14 patients. Non-leukaemic patients who had received no previous treatment reacted best to TBI (ten complete remissions in 13 patients). We consider TBI a helpful treatment in non-leukaemic patients with advanced lymphosarcoma.
D000328:Adult; D000368:Aged; D001773:Blood Cells / Q000528:radiation effects; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000532:radiotherapy*; D008297:Male; D008722:Methods; D008875:Middle Aged; D010198:Pancytopenia / Q000209:etiology; D010865:Pilot Projects; D011882:Radiotherapy, High-Energy / Q000009:adverse effects