Effect of caffeine on the memory of the mouse.
Albino mice were injected i.p. with caffeine (27.9 mg/kg) 10 min pre-trial. The mice had no trial retention (300-s period) after 24 h. This result suggests that caffeine, at this dose, would upset some mechanism involved in memory processes. No correlation is observed between serotonin (5-HT) increase and caffeine's effect on retention.
D000818:Animals; D001933:Brain Stem / Q000187:drug effects / Q000378:metabolism; D002110:Caffeine / Q000494:pharmacology*; D008297:Male; D008568:Memory / Q000187:drug effects*; D051379:Mice; D012701:Serotonin / Q000378:metabolism
D012701:Serotonin; D002110:Caffeine