Effect of irradiation and chemotherapeutic agents on the capillaries of Ehrlich ascites carcinoma of mice.
The effect of irradiation and chemotherapeutic agents on the capillaries of experimental solid tumours was analysed by the resin cast method. The most evident change of the 5 vascular layers was rarefaction of the newly produced extruding capillaries on the surface of the tumour mass, which was related to the tumour growth.
D000818:Animals; D001761:Bleomycin / Q000008:administration & dosage / Q000494:pharmacology*; D002196:Capillaries / Q000187:drug effects / Q000473:pathology* / Q000528:radiation effects; D002286:Carcinoma, Ehrlich Tumor / Q000098:blood supply / Q000188:drug therapy / Q000532:radiotherapy; D003037:Cobalt Radioisotopes; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000494:pharmacology*; D007274:Injections, Intraperitoneal; D008297:Male; D051379:Mice; D009368:Neoplasm Transplantation; D013997:Time Factors; D014184:Transplantation, Homologous
D003037:Cobalt Radioisotopes; D001761:Bleomycin; D005472:Fluorouracil