Determination of meningococcal antibodies by microassay.
A modified microassay procedure, using triphenyltetrazolium chloride as a germination indicator, was compared with a macroassay method proposed by the World Health Organization for determining the level of antibodies before and after immunization with Group A meningococcal polysaccharide vaccine. There was excellent agreement between the results obtained by the two methods. The vaccine used appeared to be safe and immunogenic.
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D001428:Bacterial Vaccines / Q000276:immunology*; D006801:Humans; D008722:Methods; D009345:Neisseria meningitidis / Q000276:immunology*
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines