[Parathyphoid B-antigen containing a complex of protective surface antigens].
The authors obtained a complex antigen from paratyphoid B bacilli containing complete O-, K- and H-antigens. The preparation was nontoxic and was characterised by marked antigenic properties. In intravenous and oral administration it stimulated production of specific O-, K-, and H-antibodies in high titres. Complex paratyphoid B antigen possessed a marked protective activity and provided intense immunity in subcutaneous and oral administration to experimental animals.
D000284:Administration, Oral; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis / Q000096:biosynthesis; D000942:Antigens, Bacterial / Q000032:analysis; D007117:Immunization, Secondary; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D051379:Mice; D010284:Paratyphoid Fever / Q000517:prevention & control*; D011817:Rabbits; D012484:Salmonella paratyphi B / Q000276:immunology; D014436:Typhoid-Paratyphoid Vaccines / Q000008:administration & dosage* / Q000032:analysis; D014611:Vaccination
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D014436:Typhoid-Paratyphoid Vaccines
Issledovanie paratifoznogo B-antigena, soderzhashchego kompleks protektivnykh poverkhnostnykh antigenov.