New derivatives of 6-hyroxy-coumaranone-2-acetic acid with anti-prostaglandin activity.
Sixteen new amide and ether derivatives of 6-hydroxy-coumaranone-2-acetic acid (1) were synthetized, some of which were screened pharmacologically for anti-prostaglandin activity.
D001572:Benzofurans / Q000138:chemical synthesis / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D016861:Cyclooxygenase Inhibitors; D013329:Structure-Activity Relationship
D001572:Benzofurans; D016861:Cyclooxygenase Inhibitors