title: [The primary structure of the Bence-Jones protein Kue. The amino acid sequence of the variable part of a human L-chain of the kappa-type (author's transl)].
abstract: The complete primary structure of the variable region of Bence-Jones protein Kue was elucitated with the aid of a few tryptic peptides, as well as one chymotryptic and one BNPS-scatol fragment. As a consequence of the evident homologies to other proteins this protein belongs to subgroup k/I. Protein Kue has some amino acid exchanges in certain positions in common with other proteins, probably giving rise to a new sub-subgroup. The constant region shows no amino acid exchanges in comparison with other human kappa L-chains. With valine covering position 191, protein Kue should be grouped per definition as an allotype Km (3).
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D001536:Bence Jones Protein; D014644:Genetic Variation; D006801:Humans; D007147:Immunoglobulin Light Chains; D007145:Immunoglobulin kappa-Chains; D010446:Peptide Fragments / Q000032:analysis; D014357:Trypsin
chemical_list: D000596:Amino Acids; D007147:Immunoglobulin Light Chains; D007145:Immunoglobulin kappa-Chains; D010446:Peptide Fragments; D001536:Bence Jones Protein; D014357:Trypsin
vernacular_title: Die Primärstruktur des Bence-Jones-Proteins Kue Aminosäuresequenz des variablen Abschnitts einer humanen L-Kette vom kappa-Typ.