Bilateral rhinocerebral phycomycosis.
A 51-year-old diabetic woman developed bilateral rhinoorbitocerebral phycomycosis. Successful treatment was accomplished by correction of the ketoacidosis, surgical debridement, and amphotericin B therapy. Rhinoorbitocerebral phycomycosis is a fulminant and frequently fatal disease most often seen in debilitated hosts. This survival suggests that aggressive therapy is indicated in patients with extensive fungal involvement.
D000666:Amphotericin B / Q000627:therapeutic use*; D001927:Brain Diseases / Q000150:complications / Q000628:therapy*; D016883:Diabetic Ketoacidosis / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications / Q000628:therapy*; D009668:Nose Diseases / Q000150:complications / Q000628:therapy*; D012233:Rhizopus
D000666:Amphotericin B