Distribution of gold in blood during chrysotherapy.
Measurements have been made using electrophoresis and neutron activation analysis of the distribution of gold in the blood of four patients who have responded well to chrysotherapy for rheumatoid arthritis. It has been shown that in these patients there is litte, if any, binding to the fibrinogen. The majority of protein-bound gold is associated with the albumin but significant amounts are bound to the other proteins. There is a small amount of gold associated with the blood cells.
D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D001798:Blood Proteins / Q000378:metabolism; D006046:Gold / Q000097:blood*; D006052:Gold Sodium Thiomalate / Q000627:therapeutic use*; D006801:Humans; D011485:Protein Binding
D001798:Blood Proteins; D006052:Gold Sodium Thiomalate; D006046:Gold