title: [Hyaluronidase in meningococcus].
abstract: A total of 204 meningococcus strains were tested for the presence of hyaluronidase, and 45.5% of the strains were found to contain it. Strains penetrating into the cerebrospinal fluid were the ones which largely produced the enzyme (in 83% of the cases). The enzyme was revealed only in 25.5% of the strains habituating on the nasopharyngeal mucosa. Hyaluronidase was mostly found in the meningococcus strains referred to the serological group A; strains of other serological groups and ungrouped strains produced the enzyme in 23.7% of the case only. There was no correlation between the capacity to form hyaluronidase and the virulence determinable in intraperitoneal infection of mice.
mesh_terms: D006821:Hyaluronoglucosaminidase / Q000096:biosynthesis / Q000302:isolation & purification*; D008585:Meningitis, Meningococcal / Q000382:microbiology; D009345:Neisseria meningitidis / Q000145:classification / Q000201:enzymology* / Q000472:pathogenicity; D014774:Virulence
chemical_list: D006821:Hyaluronoglucosaminidase
vernacular_title: Gialuronidaza u meningokokka.