Efficacy of inactivators against 14 disinfectant substances.
More than 24 inactivators were tested for their suitability against 14 disinfectant substances by a quantitative suspension test. Even simple inactivators were found to be efficace: 0.1% cysteine and 0.5% sodium thiosulfate for mercuric chloride and the iodophor; 0.1% sodium sulfite for these two substances and for the QAC in the lower concentration; 1.0% polysorbate 80 for hexylresorcinol, o-phenylphenol and the QAC in the lower concentration; 0.5% sodium thioglycolate for mercuric chloride, the iodophor and chloramine-T. The inactivator active against most disinfectants was the combination LPHT or 0.3% lecithin / 3.0% polysorbate 80 /0.1% histidine / 0.5% sodium thiosulfate. Also active were: LPWT (0.5% lecithin / 1.0% polysorbate 80 /1.0% Lubrol W / 1.0% sodium thiosulfate), LPT (2.0% lecithin / 2.0% polysorbate 80 / 0.5% sodium thiosulfate) and PS (3.0% polysorbate 80 / 3.0% saponin).
D004202:Disinfectants / Q000037:antagonists & inhibitors*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D006639:Histidine / Q000494:pharmacology; D010713:Phosphatidylcholines / Q000494:pharmacology; D011136:Polysorbates / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013885:Thiosulfates / Q000494:pharmacology
D004202:Disinfectants; D010713:Phosphatidylcholines; D011136:Polysorbates; D013885:Thiosulfates; D006639:Histidine