title: Biological and clinical effects of a partially thiolated polycytidylic acid (MPC): a potent inhibitor of DNA synthesis in RNA tumor viruses.
mesh_terms: D000818:Animals; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004279:DNA, Viral / Q000096:biosynthesis; D005260:Female; D005622:Friend murine leukemia virus / Q000187:drug effects; D006801:Humans; D007942:Leukemia, Experimental / Q000188:drug therapy; D007945:Leukemia, Lymphoid / Q000188:drug therapy*; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D008297:Male; D051379:Mice; D019384:Nucleic Acid Synthesis Inhibitors; D011066:Poly C / Q000494:pharmacology* / Q000627:therapeutic use; D011131:Polyribonucleotides / Q000494:pharmacology*; D012190:Retroviridae / Q000187:drug effects; D018894:Reverse Transcriptase Inhibitors; D013873:Thionucleotides / Q000494:pharmacology* / Q000627:therapeutic use; D014779:Virus Replication / Q000187:drug effects*
chemical_list: C010218:5-mercaptopolycytidylic acid; D004279:DNA, Viral; D019384:Nucleic Acid Synthesis Inhibitors; D011131:Polyribonucleotides; D018894:Reverse Transcriptase Inhibitors; D013873:Thionucleotides; D011066:Poly C