[Lipid thesaurismosis rheumatism. Joint manifestation during glucocerebrosidase deficiency (Gaucher's disease). Ultrastructural study of the synovial membrane].
Articular inflammatory involvement may be the first sign of gluocecerebrosidase deficiency (Gaucher's disease). Electron microscope study shows specific synovial storage lesions which explain arthritic manifestations. Furthermore presence  of mitochondrial microcrystals, (apatite?), suggest microcrystal pathogenesis of Gaucher's arthritis.
D000328:Adult; D001168:Arthritis / Q000209:etiology*; D001706:Biopsy; D005260:Female; D005776:Gaucher Disease / Q000150:complications* / Q000473:pathology; D005959:Glucosidases / Q000172:deficiency*; D005962:Glucosylceramidase / Q000172:deficiency*; D006801:Humans; D007719:Knee Joint / Q000473:pathology / Q000648:ultrastructure; D013583:Synovial Membrane / Q000473:pathology / Q000648:ultrastructure*
D005959:Glucosidases; D005962:Glucosylceramidase
Le rhumatisme des thésaurismoses à lipides. Atteinte articulaire au cours de la carence en glucocérébrosidase (maladie de Gaucher. Etude ultrastructurale de la synoviale.