Radiation effects of iodine-125 and iodine-131 on the overactive rat thyroid.
The effects of graded doses of iodine-125 and iodine-131 on rat thyroid glands under prolonged stimulation with oral thyrotropin-releasing hormone were assessed by histological and autoradiographic studies. No evidence for a difference in effect between iodine-125 and iodine-131 was found. The reason for this is suggested.
D000818:Animals; D004195:Disease Models, Animal; D006980:Hyperthyroidism / Q000532:radiotherapy; D007457:Iodine Radioisotopes / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D051381:Rats; D013961:Thyroid Gland / Q000528:radiation effects*; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology
D007457:Iodine Radioisotopes; D013973:Thyrotropin-Releasing Hormone