[Toxicity of 1,1,1-trichloroethane (author's transl)].
Recent reports on the toxicity and metabolism of 1,1,1-trichloroethane are reviewed. Problems studied include transformation of this substance in the body and in the environment, its short and long term toxicities in animal experiments and human experiences, possible teratogenicity and tumorigenicity, and hazards due to contact with the skin and mucosae. Presumable modification of toxicity by inhibitors and other chemicals as well as physical conditions are also briefly discussed.
D000328:Adult; D000818:Animals; D000975:Antioxidants / Q000633:toxicity; D002273:Carcinogens; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004347:Drug Interactions; D004781:Environmental Exposure; D005260:Female; D006168:Guinea Pigs; D000882:Haplorhini; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000633:toxicity*; D008297:Male; D051379:Mice; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced; D010705:Phosgene; D011247:Pregnancy; D011817:Rabbits; D051381:Rats; D013696:Temperature; D013723:Teratogens; D014240:Trichloroethanes / Q000378:metabolism / Q000633:toxicity*
D000975:Antioxidants; D002273:Carcinogens; D006843:Hydrocarbons, Chlorinated; D013723:Teratogens; D014240:Trichloroethanes; D010705:Phosgene