Effect of heparin on the metabolism of putrescine in vivo.
Rats and guinea pigs which are given heparin metabolize intraperitoneally injected [14C]-putrescine to 14CO2 at reduced rates. The results have been considered in relation to the heparin-induced liberation of diamine oxidase from tissues into the blood stream.
D015107:4-Butyrolactone / Q000494:pharmacology; D006631:Amine Oxidase (Copper-Containing) / Q000097:blood; D000818:Animals; D006168:Guinea Pigs; D006493:Heparin / Q000494:pharmacology*; D008297:Male; D011700:Putrescine / Q000378:metabolism*; D051381:Rats
D006493:Heparin; D006631:Amine Oxidase (Copper-Containing); D015107:4-Butyrolactone; D011700:Putrescine