Identification of antibiotics of iturin group in various strains of Bacillus subtilis.
Thirty eight strains of B. subtilis were tested for the presence of antifungal antibiotics of the iturin group. The characterization of these antibiotics was made on the basis of: antifungal activity against P. chrysogenum, isolation and purification of the active substance, quantitative analysis of alpha-aminoacids and identification of the liposoluble dipeptide obtained by partial hydrolysis. The only antibiotics of the iturin group found were: iturin A, mycosubtilin and bacillomycin L.
D000935:Antifungal Agents / Q000032:analysis / Q000096:biosynthesis* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000378:metabolism*; D006868:Hydrolysis; D010408:Penicillium chrysogenum / Q000187:drug effects; D010456:Peptides, Cyclic
D000935:Antifungal Agents; D010456:Peptides, Cyclic; C013579:iturin A