[Franklin's disease associated with chronic active hepatitis and hypothyroidism. One case (author's transl)].
The authors report on a new case of Franklin's disease; the originality of which lies in the fact that it was associated with hypothyroïdism and mainly with B virus chronic active hepatitis. It seems likely that chronic antigenic stimulation during active hepatitis played role in the pathogenesis of the monoclonal gammapathy.
D000368:Aged; D000956:Antigens, Viral / Q000276:immunology; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D006362:Heavy Chain Disease / Q000150:complications* / Q000175:diagnosis; D006509:Hepatitis B / Q000150:complications* / Q000276:immunology; D006801:Humans; D007037:Hypothyroidism / Q000150:complications*; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000096:biosynthesis; D007143:Immunoglobulin Heavy Chains / Q000032:analysis; D007142:Immunoglobulin gamma-Chains / Q000032:analysis; D014384:Tuberculosis, Female Genital / Q000175:diagnosis; D014591:Uterine Diseases / Q000175:diagnosis
D000956:Antigens, Viral; D007074:Immunoglobulin G; D007143:Immunoglobulin Heavy Chains; D007142:Immunoglobulin gamma-Chains
Maladie de Franklin associée à une hépatite chronique active et à une hypothyroïdie. Une observation.