title: Bacterial endocarditis on a prosthetic valve. Oral treatment with amoxicillin.
abstract: A patient with endocarditis due to Streptococcus faecalis on an aortic valvular prosthesis was successfully treated using large oral doses of amoxicillin concurrently with intramuscular administration of streptomycin. Oral therapy was employed because of a persistent reaction to intravenously administered antibiotics. Oral therapy for bacterial endocarditis occurring on an artificial valve may be attempted as a last resort when all other accepted therapeutic measures have failed.
mesh_terms: D000284:Administration, Oral; D000658:Amoxicillin / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D000667:Ampicillin / Q000031:analogs & derivatives*; D001021:Aortic Valve / Q000601:surgery; D004697:Endocarditis, Bacterial / Q000188:drug therapy*; D013293:Enterococcus faecalis / Q000187:drug effects; D006350:Heart Valve Prosthesis; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy*; D013290:Streptococcal Infections / Q000188:drug therapy*; D013307:Streptomycin / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000667:Ampicillin; D000658:Amoxicillin; D013307:Streptomycin