[Extracardiac effect of nitroglycerin in chronic ischemic heart disease according to the study of microcirculation].
Study of the dynamics of circulation in the microvessels of the eye conjunctiva under the effect of nitroglycerin in 50 patients with chronic ischemic heart disease showed short-lived dilatation of the postcapillaries and venules in most of them. Simultaneous fall in venous pressure may be evidence of a diminution of the venous tonus with a tendency to the storage of blood in the microcirculation system. The encountered shifts in the systemic hemodynamics may possibly be due to the reaction of the microcirculation channel, the labile character of which in the various "micro-areas" of the conjunctiva testifies to the complex reorganization of microcirculation under the effect of nitroglycerin.
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003228:Conjunctiva / Q000098:blood supply; D003327:Coronary Disease / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000187:drug effects*; D008875:Middle Aged; D005996:Nitroglycerin / Q000627:therapeutic use*; D014690:Venous Pressure / Q000187:drug effects*
D005996:Nitroglycerin
Ob ékstrakardial'nom vliianii nitroglitserina u bol'nykh khronicheskoĭ ishemicheskoĭ bolezn'iu serdtsa po dannym izucheniia mikrotsirkuliatsii.