title: [Oxygen transport function of hemoglobin in several neurologic diseases].
abstract: Data on the oxygen transport function of hemoglobin in patients with craniocerebral injury, cerebrovascular disorders, and epilepsy are presented. The role of 2,3-diphosphoglycerate contained in the erythrocytes, and of changes of the hemoglobin affinity to oxygen in the oxygenation of tissues in such patients is discussed. It is concluded that determinations of 2,3-diphosphoglycerate content in the erythrocytes be applied in clinical practice for diagnosing a number of nervous diseases accompanied by symptoms of cerebral hypoxia, so that the latter could be compensated in due time.
mesh_terms: D000136:Acid-Base Equilibrium; D000293:Adolescent; D000328:Adult; D000818:Animals; D001803:Blood Transfusion; D001927:Brain Diseases / Q000097:blood*; D001930:Brain Injuries / Q000097:blood; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000097:blood / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D004163:Diphosphoglyceric Acids / Q000097:blood*; D004827:Epilepsy / Q000097:blood / Q000209:etiology; D004912:Erythrocytes / Q000032:analysis / Q000378:metabolism; D006019:Glycolysis; D000882:Haplorhini; D006801:Humans; D002534:Hypoxia, Brain / Q000097:blood / Q000150:complications / Q000628:therapy; D008875:Middle Aged; D010108:Oxyhemoglobins / Q000378:metabolism*; D011817:Rabbits; D012886:Skull / Q000293:injuries
chemical_list: D004163:Diphosphoglyceric Acids; D010108:Oxyhemoglobins
vernacular_title: Kislorodotransportnaia funktsiia gemoglobina pri nekotorykh nevrologicheskikh zabolevaniiakh.