[Acute inhalation toxicity of ammonia in rabbits].
The aggressivity of ammonia at the pulmonary alveole level (intoxications in controlled ventilation) leads to an acute pulmonary oedema and cardio-vascular disfunctioning. Bradycardia is an early symptome (2,500 X 10(-6) but the real syndrome appears at 5,000 X 10(-6). Arterial pressure variations and blood gases modifications are significant, acidosis is systematic.
D000138:Acidosis / Q000139:chemically induced; D000641:Ammonia / Q000506:poisoning*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D001919:Bradycardia / Q000139:chemically induced; D001927:Brain Diseases / Q000139:chemically induced; D002245:Carbon Dioxide / Q000097:blood; D002318:Cardiovascular Diseases / Q000139:chemically induced; D004305:Dose-Response Relationship, Drug; D010100:Oxygen / Q000097:blood; D011654:Pulmonary Edema / Q000139:chemically induced; D011817:Rabbits; D013997:Time Factors
D002245:Carbon Dioxide; D000641:Ammonia; D010100:Oxygen
Toxicité aiguë par voie aérienne du gaz ammoniac chez le Lapin.