[Studies on the duration of the DNA synthesis in the myocardium of young rats (author's transl)].
In 150 young (14-day-old) rats the duration of the DNA synthesis of myocytes and interstitial cells of the heart was investigated by double-labelling with 3H-thymidine, and by the technique of %-labelled mitoses. Both these methods showed the S-phase to last about 10 h for each of the above 2 cell types. The inhibition of muscle cell proliferation which takes place in the early stages of the postnatal heart growth does not seem to be caused primarily by a disturbance of their S-phase.
D000818:Animals; D002453:Cell Cycle; D004247:DNA / Q000096:biosynthesis*; D007553:Isotope Labeling / Q000379:methods; D007700:Kinetics; D008938:Mitosis; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D013936:Thymidine / Q000378:metabolism
D004247:DNA; D013936:Thymidine
Untersuchungen über die Dauer der DNS-Synthesephase im Myokard junger Ratten.