title: Reduction in hepatic microsomal cytochromes P-450 and b5 in rats exposed to 1,2-dibromo-3-chloropropane and carbon tetrachloride: enhancement of effect by pretreatment with phenobarbital.
mesh_terms: D000818:Animals; D002251:Carbon Tetrachloride / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003580:Cytochromes / Q000378:metabolism*; D015786:Cytochromes b5; D006846:Hydrocarbons, Halogenated / Q000494:pharmacology* / Q000633:toxicity; D008099:Liver / Q000033:anatomy & histology; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism*; D009251:NADPH-Ferrihemoprotein Reductase / Q000378:metabolism; D009929:Organ Size / Q000187:drug effects; D010634:Phenobarbital / Q000494:pharmacology*; D011407:Propane / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000633:toxicity; D011506:Proteins / Q000378:metabolism; D051381:Rats; D013053:Spectrophotometry
chemical_list: D003580:Cytochromes; D006846:Hydrocarbons, Halogenated; D011506:Proteins; D015786:Cytochromes b5; D003577:Cytochrome P-450 Enzyme System; C007318:1,2-dibromo-3-chloropropane; D002251:Carbon Tetrachloride; D009251:NADPH-Ferrihemoprotein Reductase; D011407:Propane; D010634:Phenobarbital