title: Measurement of endotoxins with the limulus test in burned patients.
abstract: High titres of endotoxin as measured by the Limulus test were usually found in burned patients who had raised body temperatures, and were colonized with gram-negative bacteria; also some infected patients showed raised endotoxin without a raised temperature. Patients vaccinated with an antipseudomonas vaccine rarely showed endotoxin in their plasma but occasional plasma samples from vaccinated patients had a high titre of endotoxin which appeared unrelated to infection or to a raised temperature in the patient.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002056:Burns / Q000150:complications* / Q000382:microbiology; D004731:Endotoxins / Q000032:analysis*; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D006088:Gram-Negative Aerobic Bacteria; D006801:Humans; D008033:Limulus Test; D008297:Male; D008875:Middle Aged; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D013211:Staphylococcus aureus / Q000302:isolation & purification; D014946:Wound Infection / Q000209:etiology / Q000382:microbiology*
chemical_list: D004731:Endotoxins