Radial and linear thin-layer chromatographic prodedures compared for screening urines to detect oligosaccharidoses.
We describe a circular (radial) thin-layer chromatographic procedure for separating urinary oligosaccharides. Results were better than those obtained by a single linear development. Bands and specific patterns were finely resolved for various known oligosaccharidoses. The procedure provides a simple means of screening for these disorders.
D000328:Adult; D002239:Carbohydrate Metabolism, Inborn Errors / Q000175:diagnosis* / Q000652:urine; D002648:Child; D002675:Child, Preschool; D002855:Chromatography, Thin Layer / Q000379:methods; D005733:Gangliosidoses / Q000652:urine; D006801:Humans; D009081:Mucolipidoses / Q000652:urine; D009844:Oligosaccharides / Q000652:urine*
D009844:Oligosaccharides