title: [Effect of valinomycin on mitotic activity and ciliary movement during embryonic development].
abstract: The K+ ionophore valinomycin very quickly arrests cleavage in sea urchin and mouse eggs at concentrations ranging between 10 and 3 micron. Development of Axolotl and Xenopus eggs is not arrested before the blastula or gastrula stage. The motility of sea urchin sperm, blastulae and gastrulae is suppressed, within a few minutes, by 1-9 micron valinomycin.
mesh_terms: D000557:Ambystoma; D000818:Animals; D002923:Cilia / Q000187:drug effects / Q000502:physiology*; D005260:Female; D008297:Male; D051379:Mice; D008938:Mitosis / Q000187:drug effects*; D009068:Movement; D010063:Ovum / Q000187:drug effects*; D012617:Sea Urchins; D013081:Sperm Motility / Q000187:drug effects; D014634:Valinomycin / Q000494:pharmacology*; D014981:Xenopus
chemical_list: D014634:Valinomycin
vernacular_title: Effets de la valinomycine sur l'activité mitotique et le mouvement ciliaire pendant le développement embryonnaire.