Effects of repeated administration of chlordiazepoxide on spontaneous locomotor activity in mice.
Spontaneous locomotor activity has been studied in mice treated with single or repeated doses (five daily injections) of chlordiazepoxide. The repeated administration enhanced the stimulatory action of the lower doses of the drug, while the depressant effect of the higher doses was reduced.
D000818:Animals; D002707:Chlordiazepoxide / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects*; D013268:Stimulation, Chemical; D013997:Time Factors
D002707:Chlordiazepoxide