Provocation of pseudomoniasis with cyclophosphamide in mice.
After treatment with cyclophosphamide, a fatal syndrome was found in mice contaminated with Pseudomonas aeruginosa. The syndrome seems to be caused by P. aeruginosa from the intestine, and the liver is suspected to be the most important target organ.
D000818:Animals; D003520:Cyclophosphamide / Q000494:pharmacology*; D007165:Immunosuppression Therapy; D008099:Liver / Q000382:microbiology; D051379:Mice; D011552:Pseudomonas Infections / Q000209:etiology / Q000382:microbiology / Q000662:veterinary*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D012376:Rodent Diseases / Q000209:etiology* / Q000382:microbiology
D003520:Cyclophosphamide