title: Meningitis and bacteremia due to Neisseria meningitidis: clinical and laboratory findings in 69 cases from Orebro county, 1965 to 1977.
abstract: The records for 69 patients with meningococcal disease during 13 years in Orebro County were reviewed. The mean incidence during this period was 2.0/100 000 persons/year. The age group less than 1 year had the highest incidence, 15/100 000 infants/year. The mortality was 7.2% and sequelae were found in 13% of the patients. Four factors were significantly more frequent in the 7 patients with psycho-neurological sequelae: (1) Age greater than 40 years; (2) A condition prior to meningococcal disease that might have been associated with a lowered resistance; (3) Muscular hypertonia and/or marked irritability on admission; (4) Fever greater than 8 days after initiation of adequate treatment. Prodromal symptoms from the upper respiratory tract were noted in 50% of the cases. Signs and symptoms before and on admission, laboratory data and complicating events were analysed for each of 4 groups: meningitis without meningococcemia (12 patients); meningitis with meningococcemia (46): fulminant meningococcemia without meningitis (6); and benign meningococcemia (5).
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008585:Meningitis, Meningococcal / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality; D008589:Meningococcal Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality; D008875:Middle Aged; D009345:Neisseria meningitidis; D011379:Prognosis; D018805:Sepsis / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality; D013548:Sweden