title: Polioencephalomalacia in range cattle.
abstract: Polioencephalomalacia developed in 27 of 225 cattle grazing on 486 hectares of dry, short, grama grass pasture. Chemicals in drinking water, toxin from nitrate-utilizing ruminal bacteria, and documented poisonous plants were considered as etiologic agents. Attempts to reproduce the disease by injecting mice and dosing sheep with broth filtrate from nitrate-utilizing ruminal bacteria were not successful. Mushrooms collected from the pasture and fed to a cow did not reproduce the disease.
mesh_terms: D000818:Animals; D001409:Bacillus cereus / Q000378:metabolism; D001427:Bacterial Toxins / Q000633:toxicity; D001921:Brain / Q000473:pathology; D002417:Cattle; D002418:Cattle Diseases / Q000209:etiology* / Q000473:pathology; D004678:Encephalomalacia / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D005260:Female; D008297:Male; D051379:Mice; D010939:Plant Poisoning / Q000209:etiology / Q000473:pathology / Q000662:veterinary; D014867:Water / Q000032:analysis
chemical_list: D001427:Bacterial Toxins; D014867:Water