Platelet survival determination in atherosclerosis.
Platelet survival presently represents a useful method for the study of atherosclerosis and its consequences in patients and in animal models. The currently used technique, while time consuming, appears to be reliable and reproducible for the measurement of platelet survival and turnover rate. The test offers promise to detect and perhaps quantify the degree of active vessel wall damage. In addition, it might prove useful to identify drugs with potential as platelet suppressants. Finally, the test might be used to compare with new techniques developed or used to identify vessel damage or thrombosis proneness.
D000818:Animals; D001161:Arteriosclerosis / Q000097:blood*; D001792:Blood Platelets / Q000473:pathology*; D002470:Cell Survival; D001026:Coronary Artery Bypass; D000882:Haplorhini; D006711:Homocystine / Q000097:blood; D006801:Humans; D012306:Risk
D006711:Homocystine