Thyroid function tests in thyroxine-binding globulin deficiency.
Results are presented on two patients with complete and two with partial thyroxine-binding globulin (TBG) deficiency. All four subjects had lowered serum thyroxine but were clinically euthyroid. While thyroid hormone uptake tests or TBG assay were effective in the recognition of such individuals, indices based on these tests were misleading in assessing their thyroid status. Results within the reference range were obtained with the Immophase Free Thyroxine assay.
D000293:Adolescent; D000328:Adult; D005260:Female; D005916:Globulins / Q000172:deficiency; D006801:Humans; D008297:Male; D008875:Middle Aged; D012712:Serum Globulins / Q000172:deficiency*; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D013975:Thyroxine-Binding Proteins / Q000172:deficiency*; D014284:Triiodothyronine / Q000097:blood
D005916:Globulins; D012712:Serum Globulins; D013975:Thyroxine-Binding Proteins; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine