[2 new esterase loci Es-14 and Es-15 in mice (genus Muc L.) : characterization by different substrates and inhibitors].
Allelic differences at an esterase locus designated Es-14 exist between Mus musculus (both inbred strains and wild Mice) and Mus spretus. This locus is expressed in a variety of tissues. Mus musculus has been assigned the allele Es-14r while Mus spretus carries the alternate alleles Es-14l. Each phenotype manifests itself as a single band of enzyme activity and F1 hybrids show two bands corresponding to the parental forms. Allozyme variation was also detected at another esterase locus, temporarily disignated as Es-15 until confirmed by current linkage analysis. A slow variant Es-15 was recorded in a Mus musculus population from Greece while inbred strains carry the Es-15m allele. Study of a Mus spicilegus population from Greece revealed the presence of a third allele, Es-15r. Substrate and inhibition characteristics are provided for both loci.
D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D004950:Esterases / Q000037:antagonists & inhibitors / Q000235:genetics* / Q000378:metabolism; D005260:Female; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D013379:Substrate Specificity
D004950:Esterases
Deux nouveaus locus d'estérases Es-14 et Es-15 chez les souris (genre Mus L.) : caractérisation par différents substrats et inhibiteurs.