title: Influence of dietary zinc on cataracts in rainbow trout (Salmo gairdneri).
abstract: The purpose of this study was to determine the cause of lens cataracts in hatchery trout fed diets containing white fish meal. After preliminary investigations, three experiments were conducted with fry of rainbow trout (Salmo gairdneri) that were fed practical-type diets containing either 40% herring meal (control diet) or 40% white fish meal with and without various mineral supplements. In all experiments, the trout fed herring meal grew well and had normal lenses. Those fed the diet containing white fish meal without supplement grew slowly and developed bilateral cataracts determined by using a slit-lamp biomicroscope. The severity of cataracts was increased by supplementing the diet with a mixture of minerals (phosphates and carbonates of calcium, sodium and potassium). Cataracts were prevented, however, with supplemental Na2EDTA or zinc but not by supplements of manganese, copper, iron or various other minerals. The metabolic alterations responsible for the zinc-deficiency cataract were not determined.
mesh_terms: D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002386:Cataract / Q000517:prevention & control / Q000662:veterinary*; D004032:Diet; D004492:Edetic Acid / Q000008:administration & dosage; D008903:Minerals / Q000008:administration & dosage; D012487:Salmonidae / Q000502:physiology*; D014337:Trout / Q000502:physiology*; D015032:Zinc / Q000172:deficiency / Q000502:physiology*
chemical_list: D008903:Minerals; D004492:Edetic Acid; D015032:Zinc