[Standardization of the seeding material in producing live anthrax vaccine].
Technology of obtaining dry concentrated seeding material of the anthrax bacillus STI-1 vaccine strain was worked out. The use of dry seeding material for making dry anthrax vaccine rendered the preparations obtained more standard, reduced the time required for their production, led to increase of AKM-SH productivity, and to greater profitability of the vaccine production. The vaccine preparations obtained with the use of dry seeding material did not differ from control by immunogenicity.
D000336:Aerosols; D000818:Animals; D000881:Anthrax / Q000276:immunology* / Q000517:prevention & control; D001408:Bacillus anthracis / Q000276:immunology*; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000302:isolation & purification / Q000592:standards*; D003470:Culture Media; D006168:Guinea Pigs; D013171:Spores, Bacterial
D000336:Aerosols; D001428:Bacterial Vaccines; D003470:Culture Media
Standardizatsiia posevnogo materiala pri proizvodstve zhivoĭ sibireiazvennoĭ vaktsiny.