[Treatment of bone marrow aplasia in phase I of acute lymphatic leukemia treatment in children].
In the first phase of treatment of acute lymphatic leukemia in children (ALL) with aggresive cytostatic protocols, the doctor is, in some patients, forced to modify the antitumor therapy over a certain period of time because of bone marrow depression. The authors attempted to pull patients with ALL through this critical phase of the disease - by administering "profilactically" Lithium Carbonate (Li2CO3) ( in order to stimulate granulopoiesis) or, if anaemia, leukopenia and thrombocytopenia had already occurred, by administering concentrates of erythrocytes, leukocytes and platelets - without discontinuing the administration of cytostatics. The results of these attempts are reported.
D000740:Anemia / Q000139:chemically induced / Q000628:therapy; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001803:Blood Transfusion; D002648:Child; D006801:Humans; D007945:Leukemia, Lymphoid / Q000188:drug therapy*; D017708:Leukocyte Transfusion; D007964:Leukocytosis / Q000139:chemically induced / Q000188:drug therapy / Q000628:therapy*; D008094:Lithium / Q000627:therapeutic use; D016651:Lithium Carbonate; D017713:Platelet Transfusion; D013921:Thrombocytopenia / Q000139:chemically induced / Q000628:therapy*
D000970:Antineoplastic Agents; D016651:Lithium Carbonate; D008094:Lithium
Pokusaji suzbijanja i lijecenja aplazije kostane srzi u I fazi lijecenja akutne limfaticne leukemije u djece.