Induction of the interferon protein in the animal: general considerations.
Serum interferon is largely produced by B and T lymphocytes and macrophages, depending on the inducer. Lymphocyte interferon is different from macrophage and fibroblast interferon. There are two alleles controlling mouse interferon production. A protein possibly related to interferon may cause hyporeactivity. Our work was supported by NIH Grant 5-RO1-02953.
D000818:Animals; D002478:Cells, Cultured; D005802:Genes, MHC Class II; D007165:Immunosuppression Therapy; D007372:Interferons / Q000096:biosynthesis* / Q000235:genetics; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D051379:Mice; D009522:Newcastle disease virus / Q000276:immunology; D014777:Virus Diseases / Q000276:immunology
D007372:Interferons