[Gentamycin activity in combination with etonium in relation to Pseudomonas aeruginosa].
Gentamicin is one of the most effective drugs for treatment of infections caused by Ps. aeruginosa. However, isolation of the strains resistant to the antibiotics was not infrequent. It was shown in the experiments with 40 cultures that the activity of gentamicin against Ps. aeruginosa increased approximately 20 times when it was used in combination with ethonium, a derivative of bis-quaternary ammonium compounds.
D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004357:Drug Synergism; D005839:Gentamicins / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*
D004338:Drug Combinations; D005839:Gentamicins; D000644:Quaternary Ammonium Compounds; C004921:Ethonium
Aktivnost' gentamitsina v sochetanii s étoniem v otnoshenii Pseudomonas aeruginosa.