Species and strain differences in target organ alkylation and toxicity by 4-ipomeanol. Predictive value of covalent binding in studies of target organ toxicities by reactive metabolites.
D000478:Alkylation; D000818:Animals; D006224:Cricetinae; D004305:Dose-Response Relationship, Drug; D005663:Furans / Q000378:metabolism / Q000633:toxicity; D006168:Guinea Pigs; D007928:Lethal Dose 50; D008297:Male; D008647:Mesocricetus; D051379:Mice; D008815:Mice, Inbred Strains; D009251:NADPH-Ferrihemoprotein Reductase / Q000378:metabolism; D009928:Organ Specificity; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013729:Terpenes / Q000378:metabolism* / Q000633:toxicity; D014118:Toxins, Biological / Q000378:metabolism* / Q000633:toxicity
D005663:Furans; D013729:Terpenes; D014118:Toxins, Biological; D009251:NADPH-Ferrihemoprotein Reductase; C001470:4-ipomeanol