[Determination of the internal association constant as a measure of the affinity of erythocyte-fixed antibodies that interact with mono- and multivalent antigens].
The fraction of antibody-bound determinants of a polyvalent antigen is determined by the fraction of free antigen molecules and the valence of the antigen. The internal association constant for antibodies fixed onto erythrocytes can be found by the suspension method, the index obtained in this process being similar when both monovalent and polyvalent antigens are used. The sensitivity of the antibody-erythrocyte diagnostic preparation in the passive hemagglutinin test depends on the affinity of the active centers of antibodies.
D000906:Antibodies / Q000276:immunology*; D000915:Antibody Affinity; D000937:Antigen-Antibody Reactions; D000942:Antigens, Bacterial / Q000276:immunology; D000939:Epitopes; D004912:Erythrocytes / Q000276:immunology*; D006386:Hemagglutination Tests; D007120:Immunochemistry; D008433:Mathematics; D008970:Molecular Weight; D009500:Neutralization Tests; D015010:Yersinia pestis / Q000276:immunology
D000906:Antibodies; D000942:Antigens, Bacterial; D000939:Epitopes
Opredelenie vnutrenneĭ konstanty assotsiatsii kak mery affiniteta fiksirovannykh na éritrotsitakh antitel, vzaimodeĭstvuiushchikh s mono- i mnogovalentnym antigenami.