title: Properties of the membrane current of rod outer segments.
abstract: The membrane current of single rod outer segments in pieces of isolated toad retina was recorded with a glass suction electrode. Light evoked a slow net outward photocurrent consisting of a reduction in the steady inward dark current. In very dim light, the photocurrent broke up into discrete shot effects with a rounded shape and an amplitude of about 1 pA. These events were shown to result from photoisomerization of single rhodopsin molecules. The current in darkness showed fluctuations consisting of (a) discrete events apparently resulting from thermal isomerization of rhodopsin molecules, and (b) smaller amplitude shot effects shaped by two of the four rate processes of the light response.
mesh_terms: D000818:Animals; D002024:Bufo marinus; D003623:Dark Adaptation; D005071:Evoked Potentials; D008564:Membrane Potentials; D010775:Photic Stimulation; D010786:Photoreceptor Cells / Q000502:physiology*; D012243:Rhodopsin / Q000502:physiology
chemical_list: D012243:Rhodopsin