Prenatal development of acid beta-glycosidases in the rat liver, effect of triiodothyronine or cortisone administered to pregnant rats.
We have found that acid beta-galactosidase, beta-glucuronidase and N-acetyl-beta-glucosaminidase in the rat fetal liver increase during the last week of pregnancy. These enzyme activities were influenced by treatment of pregnant rats (daily from day 16) with L-tri-iodothyronine (20 or 50 microgram/100 gm b.w.) or cortisone acetate (10 or 50 mg/100 gm b.w.) as studied in their fetuses obtained on day 22 by caesarian section.
D000118:Acetylglucosaminidase / Q000378:metabolism; D000818:Animals; D003348:Cortisone / Q000494:pharmacology*; D005260:Female; D005966:Glucuronidase / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000378:metabolism*; D008099:Liver / Q000196:embryology* / Q000201:enzymology; D011247:Pregnancy; D051381:Rats; D014284:Triiodothyronine / Q000494:pharmacology*; D001616:beta-Galactosidase / Q000378:metabolism
D014284:Triiodothyronine; D006026:Glycoside Hydrolases; D001616:beta-Galactosidase; D005966:Glucuronidase; D000118:Acetylglucosaminidase; D003348:Cortisone