Changes in peripheral hormone levels after therapeutic abortion.
Plasma levels of progesterone, 17 alpha-OH progesterone, hPL and beta-subunit hCG were measured in a group of women for 24 h after therapeutic abortion. Progesterone, hCG and hPL levels fell more rapidly than 17 alpha-OH progesterone levels. This might suggest that the main site of synthesis of 17 alpha-OH progesterone is probably in the corpus luteum of pregnancy or that the prolonged half-life of hCG maintains the corpus luteum to secrete longer. Human placental lactogen fell dramatically within 4 h but the hCG level was maintained. This difference probably reflects only the differences in half-lives of these hormones.
D019326:17-alpha-Hydroxyprogesterone; D000032:Abortion, Therapeutic; D006063:Chorionic Gonadotropin / Q000097:blood*; D018997:Chorionic Gonadotropin, beta Subunit, Human; D005260:Female; D006801:Humans; D006908:Hydroxyprogesterones / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D010928:Placental Lactogen / Q000097:blood*; D011247:Pregnancy; D011374:Progesterone / Q000097:blood*
D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D006908:Hydroxyprogesterones; D010446:Peptide Fragments; D011374:Progesterone; D019326:17-alpha-Hydroxyprogesterone; D010928:Placental Lactogen