title: Neither dorsal root nor baroreceptor afferents are necessary for eliciting the renal responses to acute intravascular volume expansion in the primate Macaca fascicularis.
abstract: We determined the contribution of the dorsal roots, vagi, and sino-aortic nerves to the renal responses to acute isotonic, isooncotic intravascular volume expansion in the nonhuman primate, Macaca fascicularis. Expansion of the estimated blood volume by 15% produced a significant natriuresis and diuresis. There was no significant difference between the time to peak response for either. Neither dorsal rhizotomy (C6-T7) nor vagotomy and sino-aortic denervation had a significant effect on these responses. We conclude that these pathways are not necessary for eliciting the renal responses to hypervolemia in the nonhuman primate.
mesh_terms: D000344:Afferent Pathways / Q000502:physiology*; D000818:Animals; D001810:Blood Volume; D005727:Ganglia, Spinal / Q000502:physiology* / Q000601:surgery; D000882:Haplorhini; D006439:Hemodynamics; D007668:Kidney / Q000502:physiology*; D008252:Macaca fascicularis; D008297:Male; D011188:Potassium / Q000652:urine; D011311:Pressoreceptors / Q000502:physiology*; D012964:Sodium / Q000652:urine; D013997:Time Factors; D014867:Water / Q000378:metabolism
chemical_list: D014867:Water; D012964:Sodium; D011188:Potassium