title: [Arterial hypertension from secretion of catecholamines in an infant with a ganglioneuroblastoma].
abstract: The case of a 16 month old infant presenting with an abdominal tumour and systemic hypertension is reported. The profile of urinary plasma and tumour catecholamine levels corresponded with that of a pheochromocitoma. The combination of alphablockers and betablockers was the only effective treatment of the peaks of preoperative hypetension. The tumour was completely excised and was found to be a ganglioneuroblastoma. No recurrence has been observed after 3 years post-operative follow-up. The incidence and mechanisms of hypertension in neuroblastoma are reviewed. Only these histological forms of ganglioblastoma have the enzymatic set up for the synthesis and release of pressor amines.
mesh_terms: D000008:Abdominal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000378:metabolism*; D000310:Adrenal Gland Neoplasms / Q000378:metabolism; D002395:Catecholamines / Q000378:metabolism*; D002675:Child, Preschool; D005260:Female; D005729:Ganglioneuroma / Q000150:complications / Q000175:diagnosis / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology*; D007223:Infant; D008297:Male; D009447:Neuroblastoma / Q000150:complications / Q000378:metabolism; D010673:Pheochromocytoma / Q000378:metabolism
chemical_list: D002395:Catecholamines
vernacular_title: Hypertension artérielle par sécrétion de catécholamines chez un nourrisson porteur d'un ganglioneuroblastome.