[Mannosylation of lipid and protein acceptors in sheep lung microsomes].
In Sheep lungs, we have shown that a mannosyl-transferase activity is involved at microsomal level. This enzymatic system is able to catalyze the incorporation of mannose from GDP-mannose into two different endogenous acceptors: lipids and proteins. The mannolipid has the properties of a mannosyl-phosphoryl-polyprenol. The kinetic studies of product biosynthesis demonstrate that no precursor-product relationship exists in this system; this is an original behaviour of the lung in glycosylation phenomenon.
D000818:Animals; D004287:Dolichol Monophosphate Mannose / Q000096:biosynthesis / Q000378:metabolism; D006155:Guanosine Diphosphate Mannose / Q000378:metabolism; D006602:Hexosyltransferases / Q000378:metabolism*; D008168:Lung / Q000378:metabolism*; D008358:Mannose / Q000378:metabolism*; D008364:Mannosyltransferases / Q000378:metabolism*; D008861:Microsomes / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism; D012756:Sheep / Q000378:metabolism*
D011506:Proteins; D006155:Guanosine Diphosphate Mannose; D004287:Dolichol Monophosphate Mannose; D006602:Hexosyltransferases; D008364:Mannosyltransferases; D008358:Mannose
Mannosylation des accepteurs lipidiques et protéiniques des microsomes de poumons de mouton.