[Criteria for the evaluation of the antirheumatic (antiinflammatory) drugs in man].
Comparison of 5 antiinflammatory drugs and placebo in a double blind, short term, cross-over trial conducted in patients suffering from rheumatoid arthritis. 15 measurements were used and studied. With classical unidimensional statistical tests it was not possible to discriminate active drugs between them. Multidimensional analysis (correspondance analysis and discriminant analysis) are more sensitive and allow us to distinguish active drugs with only 11 criterion.
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004341:Drug Evaluation / Q000379:methods; D006801:Humans
D000893:Anti-Inflammatory Agents
Etudes d'un système de critéres pour l'évaluation, chez l'Homme, de l'effet des médicaments anti-rhumatismaux (anti-inflammatoires).