title: Parenteral nutrition in toxic septic states.
abstract: An analysis is made of two groups each of 20 patients with toxic septic states and hypercatabolic renal failure, who were given parenteral nutrition for at least 3 days. Each group was divided into two subgroups, given glucose, 13--20 and 20--27 kcal. 24 h--1 kg--1 body weight; the second subgroup was also given nitrogen-containing infusions of 0.05--0.12 or 0.12--0.17 g of N 24--1/kg--1 body weight, the total calorie intake amounting to 23--28 and 28--33 kcal. 24 h--1 kg--1 respectively, with nitrogen amounting to 150--400 kcal./g. A mean daily decrease of blood urea of 9.2 mg/100 ml was recorded, together with a positive catabolism in the series given nitrogen, and a rise of 0.8 mg/100 ml with negative catabolic index in the series fed with glucose (P less than 0.01); there were similar nitrogen losses in both the series, corrected by catabolism formula. The results demonstrated a decreased rate of catabolism in patients fed with a diet containing nitrogenous compounds.
mesh_terms: D058186:Acute Kidney Injury / Q000378:metabolism / Q000628:therapy*; D000328:Adult; D001424:Bacterial Infections / Q000378:metabolism / Q000628:therapy*; D002056:Burns / Q000628:therapy; D002149:Energy Intake; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000628:therapy; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D010195:Pancreatitis / Q000628:therapy; D010288:Parenteral Nutrition / Q000379:methods*; D010538:Peritonitis / Q000628:therapy; D018805:Sepsis / Q000628:therapy; D013203:Staphylococcal Infections / Q000628:therapy; D014552:Urinary Tract Infections / Q000628:therapy
chemical_list: D009584:Nitrogen