Increase of phosphoribosylpyrophosphate levels in cultured L1210 leukemia cells exposed to methotrexate.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D007042:Hypoxanthines / Q000494:pharmacology; D007939:Leukemia L1210 / Q000378:metabolism*; D008727:Methotrexate / Q000494:pharmacology*; D051379:Mice; D010428:Pentosephosphates / Q000378:metabolism*; D010754:Phosphoribosyl Pyrophosphate / Q000378:metabolism*; D010770:Phosphotransferases / Q000378:metabolism*; D012268:Ribose-Phosphate Pyrophosphokinase / Q000378:metabolism*
D007042:Hypoxanthines; D010428:Pentosephosphates; D010754:Phosphoribosyl Pyrophosphate; D010770:Phosphotransferases; D012268:Ribose-Phosphate Pyrophosphokinase; D008727:Methotrexate