[Study of the tropism of sodium Selenium-75-selenite to experimental cancer of the mammary gland].
On 25 rats with DMBA induced mammary gland adenocarcinoma, there was shown the capacity of a tumoritropic labelled preparation sodium selenium-75-selenite be be absorbed by tumors in the amounts exceeding those in the adjacent muscle days after the administration. A coefficient of the differential accumulation characterizing the level of the isotope uptake by a tumor during the whole period of observation was 3--4. First, there was shown the possibility to use the model of mammary gland tumors induced by DMBA to test labelled tumoritropic compounds.
D015127:9,10-Dimethyl-1,2-benzanthracene; D000230:Adenocarcinoma / Q000378:metabolism*; D000818:Animals; D005260:Female; D007700:Kinetics; D008325:Mammary Neoplasms, Experimental / Q000378:metabolism*; D011868:Radioisotopes; D051381:Rats; D012643:Selenium / Q000378:metabolism
D011868:Radioisotopes; D015127:9,10-Dimethyl-1,2-benzanthracene; D012643:Selenium
Izuchenie tropnosti selena-75-selenita natriia k eksperimental'nomu raku molochnoĭ zhelezy.