Antigenic similarities between human plasma inhibitor of thrombin (At-III) and its analogues from other mammals.
Cross reactions investigated by double immunodiffusion and by immunoelectrophoresis between human plasma and plasma of 5 animal species using a specific rabbit antiserum against human At-III revealed antigenic relationships between the antithrombins of these species. But the quantitative measurements of At-III by immunologic methods (electro-immunodiffusion and radial immunodiffusion), using the rabbit antiserum, were not possible in common laboratory animals, except in baboons.
D000818:Animals; D000990:Antithrombin III / Q000276:immunology*; D002417:Cattle; D003429:Cross Reactions; D004285:Dogs; D000939:Epitopes; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D010215:Papio; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013552:Swine
D000939:Epitopes; D000990:Antithrombin III