Dietary modification of amphetamine stereotyped behaviour: the action of tryptophan, methionine, and lysine.
Rats fed diets high in tryptophan, methionine, and tryptophan plus methionine or lysine were subsequently injected with 10 mg/kg d-amphetamine. The amount of amphetamine-induced stereotyped behaviour observed varied as a function of the dietary addition, with methionine showing the greatest difference to controls, and lysine the least. Whole brain catecholamine levels and 5-hydroxytryptamine levels also showed amino acid-specific changes.
D000818:Animals; D001519:Behavior / Q000187:drug effects*; D001923:Brain Chemistry / Q000187:drug effects; D002395:Catecholamines / Q000378:metabolism; D003913:Dextroamphetamine / Q000494:pharmacology*; D004032:Diet; D006801:Humans; D008239:Lysine / Q000494:pharmacology*; D008297:Male; D008715:Methionine / Q000494:pharmacology*; D051381:Rats; D013239:Stereotyped Behavior / Q000187:drug effects*; D014364:Tryptophan / Q000494:pharmacology*
D002395:Catecholamines; D014364:Tryptophan; D008715:Methionine; D008239:Lysine; D003913:Dextroamphetamine