Cholestatic hepatitis induced by gold.
A patient with rheumatoid arthritis developed an acute intrahepatic cholestasis after 100 mg of sodium aurothiomalate. Hepatotoxicity in rheumatoid arthritis is well described following a variety of anti-inflammatory preparations but is now a rare complication of gold therapy and the literature on the subject is reviewed.
D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D001706:Biopsy; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000473:pathology; D002780:Cholestasis, Intrahepatic / Q000139:chemically induced* / Q000473:pathology; D006052:Gold Sodium Thiomalate / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D008875:Middle Aged
D006052:Gold Sodium Thiomalate