Plasma levels of malondialdehyde, a product of cyclo-oxygenase-dependent and independent lipid peroxidation in rheumatoid arthritis: a correlation with disease activity.
Plasma levels of malondialdehyde (MDA), indicating the sum of lipid peroxidation dependent and independent of cyclo-oxygenase activity, were measured in rheumatoid arthritis (RA) patients. MDA levels were increased in those patients most severely diseased. Higher levels of MDA correlated with more active RA.
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000097:blood* / Q000378:metabolism; D005260:Female; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D008314:Malonates / Q000097:blood*; D008315:Malondialdehyde / Q000097:blood*; D010084:Oxidation-Reduction; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism
D008314:Malonates; D008315:Malondialdehyde; D011451:Prostaglandin-Endoperoxide Synthases