The effect of naloxone on audiogenic seizures.
The severity of audiogenic seizures was increased in two strains of mice 5--10 min after naloxone (2 or 4 mg/kg IP). This may indicate involvement of an endorphin or enkephalin in the modulation of reactivity.
D000161:Acoustic Stimulation; D000818:Animals; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009270:Naloxone / Q000494:pharmacology*; D012640:Seizures / Q000503:physiopathology*; D013045:Species Specificity; D013268:Stimulation, Chemical
D009270:Naloxone