title: Studies on the West African I strain of Plasmodium falciparum in Aotus trivirgatus monkeys.
abstract: The West African I strain of Plasmodium falciparum was isolated from a commercial airline pilot who had an overnight stay in Nigeria. Once established in the Aotus trivirgatus griseimembra monkey, the parasite produced high parasitemias and readily infected mosquitoes. Anopheles freeborni and An. maculatus mosquitoes transmitted the infection to additional animals. Infected salivary glands were also seen in An. culcifacies. Comparative infectivity studies indicated the most susceptible mosquito to be An. freeborni, followed by An. culicifacies, An. maculatus, and An. balabacensis balabacensis. Only 2 An. albimanus mosquitoes were infected out of 450 examined. The one A. t. trivirgatus monkey inoculated with this strain had very low levels of parasitemia.
mesh_terms: D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D001029:Aotus trivirgatus / Q000469:parasitology*; D000882:Haplorhini / Q000469:parasitology*; D008288:Malaria / Q000469:parasitology* / Q000635:transmission / Q000662:veterinary; D008992:Monkey Diseases / Q000469:parasitology; D010963:Plasmodium falciparum / Q000472:pathogenicity*; D012469:Salivary Glands / Q000469:parasitology; D013997:Time Factors