Influence of lipids from Listeria monocytogenes on the course of infections due to some gram-positive bacteria in mice.
The influence of lipids from Listeria monocytogenes on the course of infections due to some gram-positive cocci Streptococcus pyogenes, Streptococcus faecalis and Staphylococcus aureus and L. monocytogenes was studied in white mice. Varying doses of the lipid preparation were administered before infection. Mortality of the animals and rate of elimination of the bacteria from the organs and blood circulation were recorded. In appropriate doses, the lipids markedly enhanced resistance to the aforementioned bacteria. Mortality was substantially reduced, and elimination of the infectious agent from tissues and blood was significantly accelerated.
D000818:Animals; D004306:Dose-Response Relationship, Immunologic; D013293:Enterococcus faecalis; D005260:Female; D007113:Immunity, Innate; D008055:Lipids / Q000008:administration & dosage*; D008089:Listeria monocytogenes; D008088:Listeriosis / Q000276:immunology* / Q000401:mortality; D008297:Male; D051379:Mice; D013203:Staphylococcal Infections / Q000276:immunology* / Q000401:mortality; D013211:Staphylococcus aureus; D013290:Streptococcal Infections / Q000276:immunology* / Q000401:mortality; D013297:Streptococcus pyogenes; D014020:Tissue Extracts / Q000008:administration & dosage*
D008055:Lipids; D014020:Tissue Extracts