Interaction of disodium cromoglycate with calcium ions in 2-propanol.
Spectral evidence is presented which indicates that calcium ions can complex with the cromoglycate anion in an organic medium containing a small amount of water. The implications of this finding for the antiasthmatic activity of disodium cromoglycate are discussed.
D000433:1-Propanol; D002118:Calcium / Q000378:metabolism*; D002122:Calcium Chloride / Q000494:pharmacology; D004205:Cromolyn Sodium / Q000494:pharmacology*; D008278:Magnesium Sulfate / Q000494:pharmacology; D008407:Mast Cells / Q000378:metabolism; D012995:Solubility; D013056:Spectrophotometry, Ultraviolet
D008278:Magnesium Sulfate; D000433:1-Propanol; D002122:Calcium Chloride; D004205:Cromolyn Sodium; D002118:Calcium