Effects of d-amphetamine and methylphenidate upon auditory threshold in the squirrel monkey.
The effects of d-amphetamine sulfate and methylphenidate hydrochloride on auditory thresholds in ten squirrel monkeys were examined using a 4.2 kHz stimulus in a free field. The results indicated that d-amphetamine raised auditory thresholds but methylphenidate did not alter the thresholds. The elevation of sensory thresholds by d-amphetamine was in agreement with previous studies suggesting that the drug acts as a behavioral depressant in diurnal animals.
D000818:Animals; D001309:Auditory Threshold / Q000187:drug effects*; D003216:Conditioning, Operant / Q000187:drug effects; D003913:Dextroamphetamine / Q000494:pharmacology*; D005260:Female; D000882:Haplorhini; D008297:Male; D008774:Methylphenidate / Q000494:pharmacology*; D012453:Saimiri
D008774:Methylphenidate; D003913:Dextroamphetamine