Modulation of gastrin release by acute changes in plasma calcium.
Gastrin release was studied in 5 hypergastrinemic patients, both during calcium infusion and EDTA infusion. In each patient, gastrin decreased in conjunction with the fall in plasma calcium, and increased during calcium infusion. Plasma gastrin and calcium levels were strongly correlated.
D000126:Achlorhydria / Q000097:blood; D000293:Adolescent; D000328:Adult; D002118:Calcium / Q000008:administration & dosage / Q000097:blood*; D004492:Edetic Acid / Q000008:administration & dosage; D005260:Female; D005755:Gastrins / Q000097:blood / Q000378:metabolism*; D006801:Humans; D006965:Hyperplasia; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D011706:Pyloric Antrum / Q000473:pathology; D012636:Secretory Rate; D015043:Zollinger-Ellison Syndrome / Q000097:blood
D005755:Gastrins; D004492:Edetic Acid; D002118:Calcium