Immunoglobulin epitopes in primates.
Non-human primate sera were investigated for the presence of various human immunoglobulin epitopes including allotypes of kappa-, gamma 1-, gamma 2-, gamma 3- and alpha 2-chains, isotypes of kappa-, gamma 1-, gamma 2-, gamma 3-, gamma 4-, alpha 1-, alpha 2- and mu-chains and iso-allotypes. The non-human primate sera comprised representatives of several species of apes, Old World Monkeys, New World monkeys and prosimians. It is concluded that non-human primate immunoglobulins have many structural similarities with those of human IgM, IgA and IgG. The extent of these similarities parallels the taxonomic classification.
D000483:Alleles; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D000939:Epitopes; D006071:Gorilla gorilla; D000882:Haplorhini; D006801:Humans; D006922:Hylobates; D007106:Immune Sera / Q000494:pharmacology; D007070:Immunoglobulin A; D007126:Immunoglobulin Allotypes; D007074:Immunoglobulin G; D007136:Immunoglobulins; D008253:Macaca mulatta; D002679:Pan troglodytes; D010215:Papio; D011110:Polymorphism, Genetic; D011817:Rabbits; D011443:Strepsirhini
D000939:Epitopes; D007106:Immune Sera; D007070:Immunoglobulin A; D007126:Immunoglobulin Allotypes; D007074:Immunoglobulin G; D007136:Immunoglobulins