title: [Contribution to the formal origin of multiple branched ossifications in the lung].
abstract: The observation of multiple ossifications in the lungs as secondary findings of the post-mortem examination of a 62-year-old male with chronic cardiac stasis and emphysema of the lung is reported. Apart from bone nodules larger branched mature bone clasps with marrow caves as well as a in most cases fibromatosis with a small focus which represents the matrix of ossification is represented. Apart from this histologically a hyperaemia with an oedema rich in protein, focal precipitation of protein with formation of a granulation tissue and later fibrosation are to be proved as presteps of nodular fibromatosis which according to the kind of the desmal ossification changes into bones. The chronic haemostasis in the pulmonary circulation is thus apparently of importance in our observation. The case is compared with literature. Up to now about 65 of such observations are reported which nearly exclusively concern old men. The etiology remains unclear.
mesh_terms: D004646:Emphysema / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000150:complications; D008171:Lung Diseases / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000473:pathology*
vernacular_title: Beitrag zur formalen Genese der multiplen verzweigten Knochenbildungen der Lunge.