[An analysis of the characteristics of the anabolic effect of insulin in rats at early periods of aging].
Studies have been made of the effects of insulin on changes in the intensity of growth of the body, skeletal muscles and some other organs, on the content of protein and glycogen in muscles, as well as on the content of glycogen in the liver in rats up to 14 days of life, when the activity of skeletal muscles exhibits mainly tonic pattern, and in rats up to 30 days when this activity is transformed into a phasic pattern. Chronic administration of insulin up to 14 days of life does not affect the growth rate and the content of protein and glycogen in muscles, but increases glycogen content of the liver. Chronic injections of insulin up to 30 days increase the growth of the body and skeletal muscles, protein and glycogen contents of muscles. Glycogen content of the liver at this period is not increased.
D000375:Aging / Q000187:drug effects* / Q000378:metabolism*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D005947:Glucose / Q000494:pharmacology; D006003:Glycogen / Q000378:metabolism; D007328:Insulin / Q000494:pharmacology*; D008112:Liver Glycogen / Q000378:metabolism; D009124:Muscle Proteins / Q000187:drug effects / Q000378:metabolism; D018482:Muscle, Skeletal / Q000187:drug effects / Q000378:metabolism; D051381:Rats
D007328:Insulin; D008112:Liver Glycogen; D009124:Muscle Proteins; D006003:Glycogen; D005947:Glucose
K analizu osobennosteĭ anabolicheskogo vliianiia insulina u krys v rannie vozrastnye periody.