[Hemodynamic and cartographic study of intravenous trinitrin in the acute stage of myocardial infarct].
12 cases of acute myocardial infarction were prescribed intravenous trinitrin. Haemodynamically, the drug invariably affected the pre-load whether the haemodynamic state was normal (group I), or disturbed by left ventricular failure (group II). Myocardial function was only improved in cases with left ventricular failure. Mapping studies, performed to assess, at least theoretically, the degree of ischaemia, only showed a transient lowering of the ST elevation compared to a control group, and limitation of the ischaemic area around the myocardial necrosis could not be proved.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D005260:Female; D006321:Heart / Q000187:drug effects; D006333:Heart Failure / Q000517:prevention & control; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D009203:Myocardial Infarction / Q000188:drug therapy*; D009206:Myocardium / Q000473:pathology; D009336:Necrosis; D005996:Nitroglycerin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*
D005996:Nitroglycerin
Etude hémodynamique et cartographique de la trinitrine intra-veineuse au stade aigu de l'infarctus du myocarde.