Increased responsiveness of electric precipitation (electrosynerese) by means of a chemical method.
Electric precipitation is a method in serological diagnostics (determination of species-specificity). Since serum protein fractions (especially immunoglobulins) and extracts from blood stains migrate in agar-gel at pH 8.2--8.6 towards the cathode they cannot be used for the determination of the species specificity. By a chemical method using glutaraldehyde authors have produced an albumin-immunoglobulin complex, altering in this way the direction of electrophoretic mobility. Treatment of the blood samples with glutaraldehyde increases the sensitivity and realiability of the method.
D001797:Blood Protein Electrophoresis; D001801:Blood Stains; D003378:Counterimmunoelectrophoresis / Q000379:methods*; D005976:Glutaral / Q000494:pharmacology; D006801:Humans; D007122:Immunoelectrophoresis / Q000379:methods*
D005976:Glutaral