Studies on periodontal conditions in asthmatic children.
The effect of extrinsic asthma on periodontal conditions was studied in a group of 30 asthmatic children. Clinical examination revealed that asthmatic children had more gingivitis than their healthy controls. The asthmatic children who received an inhaled corticosteroid as treatment had more severe gingivitis compared with asthmatic children on disodium cromoglycate treatment. The amount of plaque was not altered. The peroxidase activity was assessed from whole saliva. The results revealed that this defense mechanism was not altered in asthma. An enzyme group which is involved in inflammation, the arginine aminopeptidases, was found to be slightly elevated in the gingival fluid of asthmatic children. The results indicate that gingival inflammation is increased in asthma.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000626:Aminopeptidases / Q000378:metabolism; D001249:Asthma / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D002648:Child; D004205:Cromolyn Sodium / Q000627:therapeutic use; D005260:Female; D005891:Gingivitis / Q000209:etiology* / Q000276:immunology; D006801:Humans; D006969:Hypersensitivity, Immediate; D008297:Male; D009910:Oral Hygiene; D010544:Peroxidases / Q000378:metabolism; D012463:Saliva / Q000201:enzymology
D000305:Adrenal Cortex Hormones; D010544:Peroxidases; D000626:Aminopeptidases; D004205:Cromolyn Sodium