[Problems of the immunoprophylaxis of experimental Pseudomonas pyocyanea wound sepsis].
An experimental study showed that a multicomponent Pseudomonas aeruginosa preparation, developed by the authors and named "Pyoimmunogen", had a pronounced protective effect against the culture of P. aeruginosa, most frequently isolated in surgical clinics. The immunization of rats carried out in accordance with a specially devised scheme allowed to decrease mortality rate in experimental pyocyanic wound sepsis to 6.9%, whereas in the control animals mortality rate reached 91.5%.
D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000032:analysis / Q000633:toxicity; D004353:Drug Evaluation, Preclinical; D006168:Guinea Pigs; D007114:Immunization; D051379:Mice; D011552:Pseudomonas Infections / Q000401:mortality / Q000517:prevention & control*; D011550:Pseudomonas aeruginosa / Q000276:immunology; D011817:Rabbits; D051381:Rats; D013530:Surgical Wound Infection / Q000401:mortality / Q000517:prevention & control*; D013997:Time Factors
D000942:Antigens, Bacterial; D001428:Bacterial Vaccines
Nekotorye voprosy immunoprofilaktiki éksperimental'nogo ranevogo sinegnoĭnogo sepsisa.