title: [Effectiveness of cambendazole (Bonlam paste) in sheep invaded by tramatodes (Dicrocoelium dendriticum)].
abstract: Tests were performed to examine the effectiveness of a new form of cambendazole (Bonlam paste, produced by MSD, USA) in sheep, naturally invaded by the trematodes Dicrocoelium dendriticum. Single administration of 25 mg per 1 kg live weight induced a rapid decrease in the number of the excreted eggs of D. dendriticum, as counted during ovoscopic examination seven, ten, and fifteen days after administration of the chemical. The intenseffectiveness of the preparation, determined post mortem, was 95.1%. Despite this, several dicrocoelia with normal motility and with no changes on the cuticle or internal organs were found in all the animals dissected. The animals tolerated the treatment with no signs of side-effects.
mesh_terms: D000818:Animals; D001562:Benzimidazoles / Q000494:pharmacology*; D002159:Cambendazole / Q000494:pharmacology* / Q000627:therapeutic use; D004011:Dicrocoeliasis / Q000188:drug therapy / Q000662:veterinary*; D004013:Dicrocoelium / Q000187:drug effects*; D009824:Ointments; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy
chemical_list: D001562:Benzimidazoles; D009824:Ointments; D002159:Cambendazole
vernacular_title: Efektívnost cambendazolu (Bonlam pasta) u oviec invadovaných trematódmi Dicrocoelium dentriticum.