title: Isoniazid inhibition of the synthesis of monounsaturated long-chain fatty acids in Mycobacterium tuberculosis H37Ra.
abstract: Isoniazid inhibited C(24) and C(26) monounsaturated fatty acid synthesis in Mycobacterium tuberculosis H37Ra. Time courses of this inhibition and that of mycolic acid synthesis were similar.
mesh_terms: D005231:Fatty Acids, Unsaturated / Q000096:biosynthesis*; D007538:Isoniazid / Q000494:pharmacology*; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000378:metabolism; D009171:Mycolic Acids / Q000096:biosynthesis
chemical_list: D005231:Fatty Acids, Unsaturated; D009171:Mycolic Acids; D007538:Isoniazid