title: Chromosomal investigations in children with pyknolepsy on dipropylacetate monotherapy.
abstract: We analyzed chromosome preparations obtained from leukocytes of ten children with pyknolepsy and treated with dipropylacetate (DPA) as monotherapy. Structural or numerical aberrations were not found more frequently in our patients than in five normal children (control group).
mesh_terms: D000293:Adolescent; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations; D002877:Chromosomes, Human / Q000187:drug effects*; D004832:Epilepsy, Absence / Q000188:drug therapy*; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D014635:Valproic Acid / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D014635:Valproic Acid