title: Serological characterization of a purified reverse transcriptase from osteosarcoma of a child.
abstract: Serological analysis of the reverse transcriptase (RTase), purified from human osteosarcoma tissue, has shown that it is antigenically related to DNA polymerases from BEV and from RD-114. No cross-reactivity of the osteosarcoma RTase was observed with RTases purified from AMV, RLV, SiSV, GaLV and from human spleen of a patient with myelofibrosis.
mesh_terms: D000293:Adolescent; D000818:Animals; D000956:Antigens, Viral; D003429:Cross Reactions; D000939:Epitopes; D005260:Female; D006801:Humans; D012516:Osteosarcoma / Q000201:enzymology* / Q000382:microbiology; D012194:RNA-Directed DNA Polymerase / Q000276:immunology*; D012190:Retroviridae / Q000201:enzymology* / Q000276:immunology; D012208:Rhabdomyosarcoma / Q000382:microbiology; D012513:Sarcoma, Experimental / Q000382:microbiology
chemical_list: D000956:Antigens, Viral; D000939:Epitopes; D012194:RNA-Directed DNA Polymerase