title: [Smoking and serum alpha 1-antitrypsin in 1296 healthy men (author's transl)].
abstract: Serum alpha 1-antitrypsin (alpha 1AT) was measured by radial immunodiffusion in 1296 healthy men aged 18--50 years. Other biological criteria, including leukocyte count and alpha 2-globulins were measured and the subjects were given a detailed questionnaire on their smoking habits. Results showed a very strong positive relationship between smoking and serum alpha 1AT: the heavy smokers had a serum alpha 1AT 20% higher than the non-smokers, and among subjects who stopped smoking, the level returned rapidly to normal. There were also close interrelationships between serum alpha 1AT, smoking, leukocyte count and a alpha 2-globulins. A discussion of these results is presented.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000510:Alpha-Globulins / Q000378:metabolism; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D012129:Respiratory Function Tests; D012907:Smoking / Q000378:metabolism*; D000515:alpha 1-Antitrypsin / Q000378:metabolism*
chemical_list: D000510:Alpha-Globulins; D000515:alpha 1-Antitrypsin
vernacular_title: alpha 1-Antitrypsine et tabac, une étude de 1296 hommes sains.