Histiocytosis X. An analysis of 50 cases.
Evidence is presented to support the author's view that Letter-Siwe disease, Hand-Schüller-Christian disease and eosinophilic granuloma are but variants of a single disease entity--histiocytosis X. The clinical behaviour of the disease and its prognosis are related to the age ofonset of the disease. Details of 50 cases of histiocytosis X have been analyzed. The mean age of presentation was 15 years 4 months. The male:female ratio was 3:2, 54% of patients in this series had disease confined to the jaws and oral cavity, males being more likely than females to have disseminated disease.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000209:etiology / Q000473:pathology / Q000628:therapy; D006801:Humans; D007571:Jaw Diseases; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases; D011379:Prognosis; D012737:Sex Factors