[Effects of S-adenosylmethionine and S-adenosylhomocysteine on in vivo synthesis of noradrenaline and serotonin in different parts of the rat brain].
S-adenosylmethionine (0,1 mg/kg/ip) decreases in vivo, norepinephrine (NE) synthesis and does not affect 5-hydroxytryptamine (5 HT) synthesis in the Rat brain. S-adenosylhomocysteine (7 mg/kg/ip) increases NE synthesis and decreases 5 HT synthesis. Neither nucleoside affects dopamine synthesis.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D006710:Homocysteine / Q000031:analogs & derivatives*; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D012435:S-Adenosylhomocysteine / Q000494:pharmacology*; D012436:S-Adenosylmethionine / Q000494:pharmacology*; D012701:Serotonin / Q000378:metabolism*
D006710:Homocysteine; D012701:Serotonin; D012436:S-Adenosylmethionine; D012435:S-Adenosylhomocysteine; D009638:Norepinephrine
Effets de la S-adénosylméthionine et de la s-adénosylhomocystéine sur la synthése, in vivo, de la noradrénaline et de la sérotonine dans différentes parties du cerveau de rat.