Providing saline reacting anti-D cell typing reagent.
Since 1969, when anti-D specific IgG was made available to protect recently delivered D negative women from sensitisation by fetal D positive cells, the supply of saline acting anti-D, suitable for reagent use has diminished. The same immunized male blood donors that provide the anti-D for the production of the specific IgG used for prophylaxis may, when bled up to fourteen days after restimulation, provide a source of saline anti-D suitable for reagent use. The results of such a procedure in 12 donors are described.
D004739:England; D006801:Humans; D007106:Immune Sera / Q000600:supply & distribution; D007074:Immunoglobulin G / Q000276:immunology; D007202:Indicators and Reagents / Q000600:supply & distribution; D008297:Male; D012204:Rh-Hr Blood-Group System / Q000276:immunology*; D012965:Sodium Chloride; D013997:Time Factors
D007106:Immune Sera; D007074:Immunoglobulin G; D007202:Indicators and Reagents; D012204:Rh-Hr Blood-Group System; D012965:Sodium Chloride