[A new variety of acute non-promyelocytic leukemia with t(15;17)].
Three cases of a new variety of acute leukemia have been reported. The main features were: hyperleukocytosis made of large-sized blasts with a double shaped nucleus, few or no granulations in the cytoplasm, and in a few cell faggots or unique Auer rods; mycloperoxydase reaction was positive. This feature was associated with disseminated intravascular coagulation syndrome and t(15;17)(q22;q21) translocation in the majority of mitoses.
D000208:Acute Disease; D000293:Adolescent; D000368:Aged; D002648:Child; D002901:Chromosomes, Human, 13-15; D002902:Chromosomes, Human, 16-18; D006801:Humans; D007938:Leukemia / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic
Une nouvelle variété de leucémie aiguë non promyélocytaire avec translocation t(15;17).