title: Mutator genes--pacemakers of evolution.
abstract: Initially a genetic oddity, male recombination in Drosophilaelanogaster is now being viewed as a means of detecting mutator activity and chromosome breakage in hybridising populations and is causing us to reconsider the source and rate at which genetic variability may be generated in nature.
mesh_terms: D000818:Animals; D005075:Biological Evolution; D002869:Chromosome Aberrations; D002874:Chromosome Mapping; D004331:Drosophila melanogaster / Q000235:genetics*; D005796:Genes; D014644:Genetic Variation; D006824:Hybridization, Genetic; D008297:Male; D008540:Meiosis; D009154:Mutation; D011995:Recombination, Genetic