Mutagenic effects of sodium azide in Drosophila melanogaster.
The mutagenic effects of sodium azide (NaN3) were studied at low pH in male Drosophila melanogaster using the sex-linked recessive-lethal test. No significant increase in the mutation frequency was observed after abdominal injection of azide solutions buffered at either pH 3.8 OR 4.6. However, a weak mutagenic effect was noticed in the flies fed for 3 days on 0.1 mM azide (pH 4.6) solution.
D000818:Animals; D001386:Azides / Q000494:pharmacology*; D004331:Drosophila melanogaster / Q000235:genetics; D004353:Drug Evaluation, Preclinical; D005804:Genes, Lethal; D005808:Genes, Recessive; D005821:Genetic Techniques; D008297:Male; D009153:Mutagens
D001386:Azides; D009153:Mutagens