title: International standard for anti-Brucella abortus serum: comparison of the complement-fixing activity of the first and second international standards and the EEC standard.
abstract: Although the three standards have similar agglutinating activities, it was found that the first International Standard had about half the complement-fixing activity of the second International Standard and the EEC standard. The complement-fixing activities of the latter two standards were similar. On the basis of these results, showing that the agglutination and complement-fixation tests measure different biological activities in anti-Brucella abortus sera, the WHO Expert Committee on Biological Standardization in 1976 assigned separate unitages of agglutinating and complement-fixing activity to the second International Standard for Anti-Brucella abortus Serum.
mesh_terms: D000372:Agglutination Tests; D002003:Brucella abortus / Q000276:immunology*; D003168:Complement Fixation Tests; D005060:Europe; D005062:European Union; D007106:Immune Sera / Q000592:standards*; D007391:International Cooperation
chemical_list: D007106:Immune Sera