title: [Acute meningococcal infection (author's transl)].
abstract: Authors report 49 patients bacteriologicallyly diagnosed of acute meningococcal infection collected during a 12 months period out of a series of 76 cases diagnosed on clinical grounds. "N. meningitidis" was found in 18 blood and 43 CSF cultures. 31 cases were of the B-group, one was A-group and 17 were not typed. All of them were sulphamide resistant. Hyperthermia with vomiting, cephalea, arthralgia and seizures were the initial symptoms. All patients showed pettechiae, purpura and/or ecchymoses. Endotoxic shock was diagnosed in 26,5% of the cases. In them systolic blood pressures were under p-5. Overall mortality was 14%, and that of endotoxic patients 53%. Therapeutic routines and chemoprophylaxis are reviewed.
mesh_terms: D000208:Acute Disease; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous; D008297:Male; D008589:Meningococcal Infections / Q000134:cerebrospinal fluid* / Q000175:diagnosis / Q000188:drug therapy; D009345:Neisseria meningitidis / Q000302:isolation & purification*; D010400:Penicillin G / Q000008:administration & dosage; D012737:Sex Factors
chemical_list: D010400:Penicillin G
vernacular_title: Infección meningocócica aguda. A propósito de 49 observaciones.