An improved method for gas chromatographic determination of urinary xylitol and glucuronic, glucaric gulonic and ascorbic acids, with their values in the rat, rabbit, guinea-pig and marmoset.
1. Urinary levels of xylitol and glucuronic, glucaric, gulonic and ascorbic acids were measured in the rat, rabbit, guinea-pig and marmoset by an improved g.l.c. technique. 2. Administration of a compound (2-methylbenzanilide) known to be conjugated and excreted as a beta-glucuronide had some effect on the output of these compounds of the glucuronic acid pathway in all four species, and caused a significant decrease in gulonic acid in the rat.
D000818:Animals; D001205:Ascorbic Acid / Q000652:urine*; D002143:Callitrichinae; D002849:Chromatography, Gas / Q000379:methods; D005260:Female; D005937:Glucaric Acid / Q000652:urine*; D005965:Glucuronates / Q000652:urine*; D006168:Guinea Pigs; D000882:Haplorhini; D008297:Male; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013400:Sugar Acids / Q000652:urine*; D013997:Time Factors; D014993:Xylitol / Q000652:urine*
D005965:Glucuronates; D013400:Sugar Acids; C015252:gulonic acid; D001205:Ascorbic Acid; D005937:Glucaric Acid; D014993:Xylitol