title: Essential arginyl residues in thymidylate synthetase from amethopterin-resistant Lactobacillus casei.
mesh_terms: D001120:Arginine / Q000032:analysis*; D003854:Deoxyribonucleotides / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D007700:Kinetics; D007780:Lacticaseibacillus casei / Q000187:drug effects / Q000201:enzymology*; D008727:Methotrexate / Q000494:pharmacology*; D008780:Methyltransferases / Q000378:metabolism; D010658:Phenylglyoxal / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D013940:Thymidylate Synthase / Q000378:metabolism
chemical_list: D003854:Deoxyribonucleotides; D001120:Arginine; D008780:Methyltransferases; D013940:Thymidylate Synthase; D010658:Phenylglyoxal; D008727:Methotrexate