[Study of molecular heterogeneity and chemical nature of polymeric components of the Meningococcus cell wall].
The high-molecular fraction of substances of the cell wall of meningococci, groups A and B, isolated in free volume in gel filtration through sepharose 4B and containing both group and intergroup antigens proved to be consisting of 2 subfractions in gel-filtration through Bio-Gel A-150m. Molecular weight of the first was within the range of 100--150 million dalton, and of the second--of 3 to 100 million dalton. In dissociation in sodium deoxycholate the high molecular fraction complex compound of the cell wall of meningococcus strain, group A, isolated from the cerebrospinal fluid of a patient suffering from meningitis broke down into 5 fragments differing in chemical nature and mol wt. There were revealed protein and protein-lipopolysaccharide components with a relatively high mol wt. polypeptide components and low molecular residues of the initial lipopolysaccharide.
D001426:Bacterial Proteins / Q000032:analysis; D002473:Cell Wall / Q000032:analysis; D002555:Cerebrospinal Fluid / Q000382:microbiology; D006801:Humans; D008070:Lipopolysaccharides / Q000032:analysis; D008585:Meningitis, Meningococcal / Q000382:microbiology; D008970:Molecular Weight; D009345:Neisseria meningitidis / Q000032:analysis*; D011135:Polysaccharides, Bacterial / Q000032:analysis; D013045:Species Specificity; D013347:Subcellular Fractions
D001426:Bacterial Proteins; D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial
Izuchenie molekuliarnoĭ geterogennosti i khimicheskoĭ prirody polymernykh komponentov kletochnoĭ stenki meningokokkov.