title: Tobacco dependence: is nicotine rewarding or aversive?
mesh_terms: D000222:Adaptation, Physiological; D005260:Female; D006801:Humans; D008297:Male; D009042:Motivation; D009538:Nicotine / Q000097:blood / Q000494:pharmacology*; D010947:Plants, Toxic; D012054:Reinforcement, Psychology; D012907:Smoking / Q000523:psychology*; D013375:Substance Withdrawal Syndrome; D019966:Substance-Related Disorders / Q000523:psychology; D013638:Tars; D014026:Nicotiana
chemical_list: D013638:Tars; D009538:Nicotine