Chemical carcinogenesis of submandibular salivary gland in BALB/c mice and syngeneic passage of the tumor.
Twenty-two male BALB/c mice were used in this investigation. A pellet of dry 9,10-dimethyl-1,2-benzanthracene powder was implanted in the submandibular salivary gland. Fifteen epidermoid carcinomas and four sarcomas were induced within a period ranging from 7 to 15 weeks. Epidermoid carcinomas were sucessfully transplanted into syngeneic mice.
D015127:9,10-Dimethyl-1,2-benzanthracene; D000818:Animals; D001551:Benz(a)Anthracenes; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced / Q000473:pathology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000473:pathology; D012468:Salivary Gland Neoplasms / Q000139:chemically induced* / Q000473:pathology; D012509:Sarcoma / Q000139:chemically induced / Q000473:pathology; D013363:Submandibular Gland / Q000187:drug effects*; D014184:Transplantation, Homologous
D001551:Benz(a)Anthracenes; D015127:9,10-Dimethyl-1,2-benzanthracene