[Anabolic effectiveness of nitrogenous preparations for parenteral nutrition in the presence of toxic liver damage].
The authors studied the assimilation of nitrogen preparations--moriamin S-2 and "improved" caseine hydrolysate in parenternal administration to 100 albino rats. Healthy animals and those with toxic affection of the liver induced with CCl4 were experimented upon. In healthy animals administration of nitrogen preparations led to the change of negative nitrogen balance into a positive one, normalized the content of blood and tissue amine nitrogen deranged in protein deficiency. Assimilation of nitrogen preparations fell considerably in toxic hepatitis. An 8-day parenteral nutrition failed to change the negative nitrogen balance into positive, and did not eliminate hypoproteinemia; however, it normalized the amine nitrogen concentration in the blood and tissues.
D000596:Amino Acids / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000628:therapy*; D002364:Caseins; D056486:Chemical and Drug Induced Liver Injury / Q000378:metabolism / Q000628:therapy*; D005260:Female; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D010288:Parenteral Nutrition; D011492:Protein Hydrolysates / Q000008:administration & dosage / Q000627:therapeutic use*; D051381:Rats
D000596:Amino Acids; D002364:Caseins; D011492:Protein Hydrolysates; D009584:Nitrogen
Anabolicheskaia éffektivnost' azotistykh preparatov dlia parenteral'nogo pitaniia pri toksicheskom porazhenii pecheni.