Red cell antibody screening with the Groupamatic system. I. Bromelin methyl-cellulose and saline techniques: evaluation of five years' routine use.
These data comprise 1,231,024 routine tests carried out over a 5-year period on voluntary blood donors. The percentage of positive results on the machines varies from 1 to 3% of the total number of samples tested. Antibodies identified either by manual or automated techniques make up 15--20% of the positive screening reactions. Rhesus, Luewis and P systems prevail, whilst Duffy, Kidd and Ltheran systems are absent. This screening has three main advantages: the supply of plasma for our production of test sera, or therapeutic immunoglobulins; protection of the recipient; partial information on the donor's immunohaematological state, especially for the risk of giving him incompatible blood sometimes in the future.
D000918:Antibody Specificity; D001322:Autoanalysis; D001788:Blood Grouping and Crossmatching / Q000379:methods*; D001963:Bromelains / Q000494:pharmacology*; D004912:Erythrocytes / Q000276:immunology*; D005189:False Positive Reactions; D006801:Humans; D007518:Isoantibodies; D007983:Lewis Blood Group Antigens; D010127:P Blood-Group System; D012204:Rh-Hr Blood-Group System; D012965:Sodium Chloride / Q000494:pharmacology*
D007518:Isoantibodies; D007983:Lewis Blood Group Antigens; D010127:P Blood-Group System; D012204:Rh-Hr Blood-Group System; D012965:Sodium Chloride; D001963:Bromelains