Effect of hypocalcemic and hypercalcemic substances on the parathyroid histology of the lizard, Uromastix hardwickii (Gray).
The effects of hypocalcemic and hypercalcemic substance on activity of the parathyroid and plasma calcium and phosphorus levels in the lizard, Uromastix hardwickii are described. The cellular hypertrophy and degranulation of cytoplasm in the parathyroid cells along with decrease in plasma calcium level appeared after sodium citrate and ethylenediaminetetraacetate (EDTA) treatment. On the other hand, degenerative changes are observed after calcium chloride treatment. It is suggested that the secretion of parathyroid is regulated by the circulating blood calcium level.
D000818:Animals; D002118:Calcium / Q000097:blood*; D002122:Calcium Chloride / Q000494:pharmacology; D002951:Citrates / Q000494:pharmacology; D004492:Edetic Acid / Q000494:pharmacology; D008116:Lizards / Q000033:anatomy & histology* / Q000097:blood; D010280:Parathyroid Glands / Q000187:drug effects / Q000648:ultrastructure*; D010758:Phosphorus / Q000097:blood*
D002951:Citrates; D010758:Phosphorus; D004492:Edetic Acid; D002122:Calcium Chloride; D002118:Calcium