title: [Epidemiology of hepatitis B (author's transl)].
abstract: A hepatitis B epidemic was observed in an institution for retarded children. The mode of transmission and the epidemiology of this disease was studied. Approximately 50% of all children in this institution were infected by the enteral route. 7 children were hospitalized with an accute episode of hepatitis B and recovered completely. 9 children showed persisting hepatitis B surface antigen and DANE-particles in the serum without clinical signs of infection. 6 of those 9 children were diagnosed as trisomy 21. All of them excrete HBs Antigen in saliva, tears and urine. 80% of family members and teaching personnel involved with these children were infected, 23% had an acute episode of hepatitis B.
mesh_terms: D002353:Carrier State; D002648:Child; D002674:Child, Institutionalized; D004196:Disease Outbreaks; D006509:Hepatitis B / Q000635:transmission*; D006511:Hepatitis B Antigens / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D008607:Intellectual Disability; D012463:Saliva / Q000276:immunology; D013666:Tears / Q000276:immunology; D014556:Urine / Q000276:immunology
chemical_list: D006511:Hepatitis B Antigens; D006514:Hepatitis B Surface Antigens
vernacular_title: Zur Epidemiologie der Hepatitis B.