Pulmonary damage associated with gold therapy. A report of two cases.
Two patients suffering from rheumatoid arthritis developed respiratory symptoms during sodium aurothiomalate treatment. Chest radiographs showed bilateral diffuse pulmonary infiltrates in both cases. In one patient the symptoms subsided and the chest radiograph became normal within 6 months after gold therapy was discontinued and steroids added. In the other patient the condition resulted in an irreversible lung damage.
D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D005260:Female; D006052:Gold Sodium Thiomalate / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008168:Lung / Q000187:drug effects; D008171:Lung Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D011859:Radiography
D006052:Gold Sodium Thiomalate