[Autotransplantion of Langerhans islets after total duodeno-pancreatectomy in a patient with chronic pancreatitis (author's transl)].
Total duodenopancreatectomy was performed in a 36-year-old man because of global chronic pancreatitis. Islets cells were isolated by collagenase digestion from the resected pancreas and re-implanted into the liver via the portal vein. Until the sixth postoperative day the amount of insulin required fell from 54 IU initially to 10 IU per day. Serial insulin determination demonstrated secretion by the implanted cells.
D000328:Adult; D002908:Chronic Disease; D006801:Humans; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use; D016381:Islets of Langerhans Transplantation; D008099:Liver / Q000601:surgery; D008297:Male; D010180:Pancreatectomy; D010195:Pancreatitis / Q000601:surgery*; D011169:Portal Vein; D011182:Postoperative Care; D013997:Time Factors; D014182:Transplantation, Autologous
D007328:Insulin
Autotransplantation von Langerhansschen Inseln nach totaler Duodenopankreatektomie bie einem Patienten met chronischer Pankreatitis.