[Effect of blockade or stimulation of the reticuloendothelial system on the blood clearance kinetics of the anticholinesterase insecticide carbaryl in the rat].
The blood clearances of 14C-carbaryl and colloïdal carbon were studied in Rats with reticuloendothelial system (RES) inhibited or activated, and in control Rats. A correlation was established between the blood clearance kinetics of carbon particles and carbaryl; such data support the concept of the contribution of the RES in the disappearance of carbaryl from the circulation.
D000818:Animals; D012721:Carbaryl / Q000378:metabolism*; D002244:Carbon / Q000494:pharmacology; D003102:Colloids; D007700:Kinetics; D012157:Mononuclear Phagocyte System / Q000187:drug effects* / Q000378:metabolism; D010587:Phagocytosis / Q000187:drug effects; D051381:Rats; D014304:Triolein / Q000494:pharmacology
D003102:Colloids; D014304:Triolein; D002244:Carbon; D012721:Carbaryl
Effet de l'inhibition ou de l'activation du système réticuloendothélial sur la cinétique de disparition sanguine d'un insecticide anticholinestérasique, le carbaryl, chez le rat.