The chemical composition and stability of bacillomycin S.
Bacillomycin S, an antifungal antibiotic from culture filtrates of Bacillus subtilis, was shown to consist of proteinaceous matter (83.6 g/100 g) and lipid material (16 g/100 g). The amino acid and fatty acid components were determined qualitatively and quantitatively. It was shown that bacillomycin S is stable at physiological pH and it is suggested that its antifungal activity resides in the intact molecule.
D000935:Antifungal Agents / Q000302:isolation & purification*; D001412:Bacillus subtilis / Q000032:analysis; D001426:Bacterial Proteins / Q000032:analysis; D055598:Chemical Phenomena; D002621:Chemistry; D004355:Drug Stability; D005227:Fatty Acids / Q000032:analysis; D010455:Peptides / Q000032:analysis; D014364:Tryptophan / Q000032:analysis; D014443:Tyrosine / Q000032:analysis
D000935:Antifungal Agents; D001426:Bacterial Proteins; D005227:Fatty Acids; D010455:Peptides; D014443:Tyrosine; D014364:Tryptophan