Temperature dependence of ADH-induced water flow and intramembranous particle aggregates in toad bladder.
Antidiuretic hormone (ADH)-induced luminal intramembranous particle aggregates and hormonally stimulated water flow in toad urinary bladder are reduced simultaneously with a reduction in temperature. When water movement is factored by the aggregation response, the apparent activation energy for this process decreases from 12.1 +/- 1.6 to 3.0 +/- 2.3 kilocalories per mole. The data are consistent with the view that the particle aggregates contain sites for transmembrane water movement and that these sites behave as pores.
D000818:Animals; D002024:Bufo marinus; D004058:Diffusion; D004848:Epithelium / Q000187:drug effects / Q000648:ultrastructure; D005260:Female; D013696:Temperature; D001743:Urinary Bladder / Q000166:cytology / Q000187:drug effects*; D014667:Vasopressins / Q000494:pharmacology*; D014882:Water-Electrolyte Balance / Q000187:drug effects*
D014667:Vasopressins