[The early diagnosis of teratogenic malformations (author's transl)].
A case of anencephaly is reported which was diagnosed at 32 weeks gestation by ultra-sound despite a family history: AFP, HPL and estriol were normal and the case was referred late. It is suggested that all pregnancies require an ultra-sound scan between 16 and 20 weeks to rule out major fetal anomalies.
D000328:Adult; D000757:Anencephaly / Q000175:diagnosis; D000013:Congenital Abnormalities / Q000175:diagnosis*; D004964:Estriol / Q000097:blood; D005260:Female; D006801:Humans; D010928:Placental Lactogen / Q000097:blood; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014463:Ultrasonography; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins; D010928:Placental Lactogen; D004964:Estriol
Zum Problem der Früherkennung teratogener Missbildungen.