title: Independence of proline chemotaxis and transport in Bacillus subtilis.
abstract: Values of KI for nine proline analogs as inhibitors of proline chemotaxis and of proline transport were determined. Two of them inhibited transport at substantially lower concentrations than chemotaxis; two at substantially higher concentrations. Moreover, mutants, believed to be in the component that binds proline, were isolated that showed a shift of KM for transport to higher concentrations, one as much as 40-fold. However, chemotaxis was virtually unaffected. Therefore, unlike galactose chemotaxis and transport in Escherichia coli, which share the galactose-binding protein, proline chemotaxis and transport in Bacillus subtilis are independent.
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D001412:Bacillus subtilis / Q000378:metabolism*; D001692:Biological Transport; D002633:Chemotaxis; D007700:Kinetics; D009154:Mutation; D011392:Proline / Q000378:metabolism*; D013045:Species Specificity
chemical_list: D000596:Amino Acids; D011392:Proline