[Light chains of warm autoantibodies in patients with autoimmune hemolytic anemia. Long-term observation].
In 18 patients with autoimmunohaemolytic anaemia presence of light chains of IgG autoantibodies was south for by the method of direct antiglobulin reaction. In 11 patients variability was observed in the detection of light chains. The authors discuss the possible causes of this observation: variable participation of different cell lines in the production of autoantibodies and changes in the conformation of immunoglobulin molecule in the erythrocyte.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000744:Anemia, Hemolytic, Autoimmune / Q000276:immunology*; D001323:Autoantibodies / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006358:Hot Temperature; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007147:Immunoglobulin Light Chains / Q000032:analysis*; D007223:Infant; D008297:Male; D008875:Middle Aged
D001323:Autoantibodies; D007074:Immunoglobulin G; D007147:Immunoglobulin Light Chains
Wieloletnia obserwacja łańcuchów lekkich autoprzeciwciał typu ciepłego u chorych z niedokrwistościa autoimmunohemolityczna.