[Study of the antigenic relationship between animal and human immunoglobulins using antisera to human immunoglobulins].
Cross-reactivity of monospecific antisera to human immunoglobulins with animal sera of 10 species was studied by immunoelectrophoresis and radial immunodiffusion. Antisera to IgG were shown to reveal IgG of all the species studied, antisera to IgM and especially to IgA cross reacted less extensively. The greatest number of cross reactions were given by the antisera obtained as a result of hyperimmunization. Hyperimmune monospecific antisera to human IgG, IgA, and IgM can be used for the identification of animal immunoglobulins during their isolation from the sera and for their quantitation by radial immunodiffusion.
D000818:Animals; D002417:Cattle; D003429:Cross Reactions; D004285:Dogs; D005260:Female; D006041:Goats; D006168:Guinea Pigs; D000882:Haplorhini; D006736:Horses; D006801:Humans; D007106:Immune Sera; D007136:Immunoglobulins / Q000302:isolation & purification*; D008253:Macaca mulatta; D051379:Mice; D008907:Mink; D011247:Pregnancy; D011817:Rabbits; D012756:Sheep; D013045:Species Specificity; D013552:Swine
D007106:Immune Sera; D007136:Immunoglobulins
Issledovanie antigennykh sviazeĭ immunoglobulinov zhivotnykh i cheloveka s pomoshch'iu antisyvorotok k immunoglobulinam cheloveka.