Aldose reductase and sorbitol dehydrogenase in the muscle of Ascaris suum (Nematoda).
The muscle of Ascaris suum contains sorbitol dehydrogenase [EC 1.1.1.14] and the apparent Km values indicate that the enzyme favours fructose formation. Aldose reductase [EC 1.1.1.21] is also present and like the mammalian enzyme it has a very high apparent Km for glucose. Possible functions of the sorbitol pathway in Ascaris muscle are discussed.
D000449:Aldehyde Reductase / Q000378:metabolism*; D000818:Animals; D001200:Ascaris / Q000201:enzymology* / Q000378:metabolism; D005260:Female; D005632:Fructose / Q000096:biosynthesis; D005947:Glucose / Q000378:metabolism; D006019:Glycolysis; D007064:L-Iditol 2-Dehydrogenase / Q000378:metabolism*; D009132:Muscles / Q000378:metabolism; D013012:Sorbitol / Q000378:metabolism; D013401:Sugar Alcohol Dehydrogenases / Q000378:metabolism*
D005632:Fructose; D013012:Sorbitol; D013401:Sugar Alcohol Dehydrogenases; D007064:L-Iditol 2-Dehydrogenase; D000449:Aldehyde Reductase; D005947:Glucose