Cerebral tissue response to reserpine: a morphological study.
The acute influence of reserpine injection on cerebral tissue was studied in baboon and rat models. Five h after the infusion of reserpine, bilateral cortical areas were found to contain perivascular changes only, whereas basal ganglia regions contained advanced oedematous responses. Mitochondrial swelling was commonly found in the latter regions, as were loci containing microvascular crenation with accompanying pericytic changes.
D000818:Animals; D001479:Basal Ganglia / Q000648:ultrastructure; D001921:Brain / Q000648:ultrastructure*; D000882:Haplorhini; D008854:Microscopy, Electron; D008928:Mitochondria / Q000648:ultrastructure; D010215:Papio / Q000033:anatomy & histology; D051381:Rats; D012110:Reserpine / Q000494:pharmacology*
D012110:Reserpine