Acetazolamide binding to two carbonic anhydrase isoenzymes in human erythrocytes.
Acetazolamide binding to high activity and low activity carbonic anhydrase isoenzymes in red blood cells was studied. Inhibitory constants of 0.041 and 2.72 microM and maximum binding capacities of 17.2 and 155 microM, respectively, were found.
D000086:Acetazolamide / Q000097:blood*; D002256:Carbonic Anhydrases / Q000097:blood*; D004912:Erythrocytes / Q000201:enzymology / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007527:Isoenzymes / Q000097:blood*; D007700:Kinetics; D011485:Protein Binding
D007527:Isoenzymes; D002256:Carbonic Anhydrases; D000086:Acetazolamide