Cyclopia associated with triploidy and hydatidiform mole: a case report.
A live 22-week-old cyclops fetus with a 69 XYY chromosome pattern and partial hydatidiform mole of the placenta is reported. Although cyclopia and chromosomal triploidy have certain features in common they appear to be two quite distinct entities. As no other 69 XYY fetus has survived to 22 weeks gestation and no other case of cyclopia has been reported with a triploid set of chromosomes, the assumption that the two conditions occurred coincidently in this fetus will have to await the accumulation of additional case reports.
D000782:Aneuploidy; D002877:Chromosomes, Human; D003241:Consanguinity; D005124:Eye Abnormalities; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000150:complications / Q000235:genetics*; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D012729:Sex Chromosome Aberrations; D014594:Uterine Neoplasms / Q000150:complications / Q000235:genetics*; D014997:XYY Karyotype