Effects of disodium chromoglycate on systemic anaphylaxis in guinea pigs, rats and mice.
Disodium chromoglycate (DSCG) exerted a protective action in passively-sensitized guinea pigs undergoing anaphylaxis but no such effect was found in actively-sensitized animals. The degree of protection depended on the route and the time of administration. DSCG also protected actively-sensitized rats undergoing anaplylaxis but no effect was found in mice.
D000707:Anaphylaxis / Q000276:immunology*; D000818:Animals; D004205:Cromolyn Sodium / Q000494:pharmacology*; D004195:Disease Models, Animal; D006168:Guinea Pigs; D007110:Immunity, Active; D007112:Immunity, Maternally-Acquired; D051379:Mice; D008807:Mice, Inbred BALB C; D051381:Rats
D004205:Cromolyn Sodium