Activity of beta-lactam antibiotics against Pseudomonas aeruginosa carrying R plasmids determining different beta-lactamases.
Azlocillin, carbenicillin, cefsulodin, mezlocillin, nocardicin A, piperacillin, pirbenicillin, sulbenicillin, and ticarcillin, but not HR756, showed reduced activity against Pseudomonas aeruginosa strains producing seven types of beta-lactamase.
D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D011815:R Factors / Q000187:drug effects; D013045:Species Specificity; D001618:beta-Lactamases / Q000235:genetics
D010406:Penicillins; D001618:beta-Lactamases