Induction of delayed-type sensitivity to Leishmania parasite in a case of leishmaniasis cutanea diffusa with BCG and cord-factor (Trehalose-6-6' dimycolate).
The delayed hypersensitivity against the leishmania parasite was restored to a patient who had suffered from diffuse cutaneous leishmaniasis (DCL) for 26 years, by the application of an ointment containing heat-killed and lyophilized BCG and cord-factor (trehalose-6-6'-dimycolate) after stripping the affected and adjacent areas with scotch-tape.
D001500:BCG Vaccine / Q000627:therapeutic use*; D002908:Chronic Disease; D003311:Cord Factors / Q000627:therapeutic use*; D005148:Facial Dermatoses / Q000628:therapy*; D006017:Glycolipids / Q000627:therapeutic use*; D006801:Humans; D006968:Hypersensitivity, Delayed; D007896:Leishmaniasis / Q000276:immunology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012874:Skin Diseases, Infectious / Q000628:therapy*
D001500:BCG Vaccine; D003311:Cord Factors; D006017:Glycolipids