title: Ultrastructure of tissue in intrabony and subperiosteal porous ceramic implants.
abstract: Porous ceramic (Al2O3) implants with pore size of 100--750 micron were placed intrabony in the maxilla and subperiosteally in the mandible of three adult monkeys. After observation periods of 10, 11 and 12 months, the animals were perfused with 1.7% glutaraldehyde and the jaws processed for electron microscopy. Tissue ingrowth into the pores was observed in all the specimens. The implant pores facing the host bone contained bone tissue to a depth of approximately 1 mm, while only unmineralized tissue was found in the implant part adjacent to the periosteum. The unmineralized tissue was of a fibrous nature with collagen fibers arranged in a lamellar fashion. Cells, often with extremely long and slender cellular processes, were seen between the lamellae. The cells had the cytoplasmic features typical of protein-producing cells. The mineralized tissue exhibited ordinary bone tissue structure with plate-like crystallites in a collagenous matrix. Some lacunae and canaliculi with osteocytes were observed, though they were scarce.
mesh_terms: D000818:Animals; D002516:Ceramics; D002521:Cercopithecus; D003094:Collagen; D003238:Connective Tissue / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D003757:Dental Implantation; D003758:Dental Implantation, Endosseous; D005069:Evaluation Studies as Topic; D000882:Haplorhini; D008055:Lipids; D008334:Mandible / Q000601:surgery* / Q000648:ultrastructure; D008437:Maxilla / Q000601:surgery* / Q000648:ultrastructure; D010011:Osteocytes / Q000648:ultrastructure
chemical_list: D008055:Lipids; D003094:Collagen