title: [Antibacterial activity of fosfomycin in chronic kidney infections].
abstract: Authors have carried out a retrospective study in vitro on the bacteria isolated from renal parenchyma and stones in patients with CPN associated to kidney stones. Results show a different inhibitory action of the some antibiotics to Proteus, E. coli and P. aeruginosa. Fosfomycin inhibits the growth of bacteria in a wide range of concentration (50-1000 microgram/ml). A prospective study in vivo shows an excellent therapeutic action of fosfomycin in recurrent urinary infections, and a very good one in CPN and in some forms associated to kidney stones.
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli; D005260:Female; D005578:Fosfomycin / Q000627:therapeutic use*; D006801:Humans; D007669:Kidney Calculi / Q000150:complications / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011511:Proteus; D011550:Pseudomonas aeruginosa; D011704:Pyelonephritis / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D005578:Fosfomycin
vernacular_title: Attività antibatterica della fosfomicina nelle infezioni renali croniche.