title: [Autotransplantation of Langerhans' islets in a case of total duodenopancreatectomy (author's transl)].
abstract: A 36-year-old man suffering from chronic pancreatitis involving the whole organ had total duodenopancreatectomy. The Langerhans' islets were isolated from the extirpated organ and transplanted into the liver via portal artery. Insulin substitution could be lowered from 50 I.U. to 12 I.U. by the 5th post operative day. Repeatedly, raised insulin levels could be verified in response to high blood sugar loads. C-peptide and glucagon were also found. 7 months after transplantation the islets still seem to be functioning.
mesh_terms: D000328:Adult; D002096:C-Peptide / Q000032:analysis; D002908:Chronic Disease; D004386:Duodenum / Q000601:surgery; D005934:Glucagon / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D016381:Islets of Langerhans Transplantation; D008099:Liver; D008297:Male; D010180:Pancreatectomy; D010195:Pancreatitis / Q000601:surgery; D014182:Transplantation, Autologous
chemical_list: D002096:C-Peptide; D007328:Insulin; D005934:Glucagon
vernacular_title: Autotransplantation Langerhansscher Inseln nach totaler Duodenopankreatektomie beim Menschen.