Cerebrovascular effects of cerebrospinal fluid removal.
The effects on cerebral blood flow of withdrawal of graded volumes of cerebrospinal fluid (CSF) from the cisterna magna were studied in 12 barbiturate-anaesthetized baboons. The results show that withdrawal of CSF was accompanied by a decreased CSF pressure, an increased CSF PCO2, a decreased CSF PO2 and an increased cerebral blood flow. The possible clinical significance of these findings is pointed out.
D000818:Animals; D001783:Blood Flow Velocity; D001784:Blood Gas Analysis; D002245:Carbon Dioxide; D002555:Cerebrospinal Fluid / Q000502:physiology*; D002560:Cerebrovascular Circulation; D005260:Female; D000882:Haplorhini; D008297:Male; D010100:Oxygen; D010215:Papio
D002245:Carbon Dioxide; D010100:Oxygen