Prostaglandin synthetase dependent activation of 7,8-dihydro-7,8-dihydroxy-geno (a) pyrene to mutagenic derivativies.
D000818:Animals; D001580:Benzopyrenes / Q000494:pharmacology; D007700:Kinetics; D008297:Male; D009153:Mutagens; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism*; D012486:Salmonella typhimurium / Q000187:drug effects; D012669:Seminal Vesicles / Q000201:enzymology; D012756:Sheep
D001580:Benzopyrenes; D009153:Mutagens; D011451:Prostaglandin-Endoperoxide Synthases