title: [The effect of various antibiotics on the formation of typhus antibodies following immunization with typhus vaccine].
abstract: It was shown that administration in the course of one week, before or after a single use of killed or chemical typhoid vaccine of dibiomycin, biomycin, or biomycin in combination with erythromycin in comparatively high doses produced no negative effect of the production of typhus antibodies and the intensity of antitoxic immunity in albino mice. The same antibiotics failed to influence the antibody formation in guinea pigs if they produced no toxic effect on the animals; but in case of development of toxic phenomena connected with the administration of the mentioned antibiotics a strong depression of antibody production was observed in guinea pigs.
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D001428:Bacterial Vaccines; D002751:Chlortetracycline / Q000494:pharmacology; D003864:Depression, Chemical; D004917:Erythromycin / Q000494:pharmacology; D006168:Guinea Pigs; D007114:Immunization; D051379:Mice; D012286:Rickettsia typhi / Q000276:immunology*; D014613:Vaccines, Attenuated
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D014613:Vaccines, Attenuated; D004917:Erythromycin; D002751:Chlortetracycline
vernacular_title: Vliianie nekotorykh antibiotikov na formirovanie protivosypnotifoznykh antitel pri immunizatsii sypnotifoznoĭ vaktsinoĭ.