The T4/TBG ratio and the investigation of thyroid function.
The relationship between serum thyroxine (T4) and thyroxine-binding globulin (TBG) has been studied in "euthyroid" subjects. The T4/TBG ratios in these subjects has been calculated and compared with those found in patients suffering from myxoedema and thyrotoxicosis. The ratio allows a more precise selection of the borderline cases requiring Thyroid Stimulating Hormone and triiodothyronine assays, particularly when the serum TBG is raised or lowered.
D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood; D008297:Male; D009230:Myxedema / Q000097:blood; D011247:Pregnancy; D012737:Sex Factors; D013960:Thyroid Function Tests / Q000379:methods; D013961:Thyroid Gland / Q000502:physiology*; D013974:Thyroxine / Q000097:blood*; D013975:Thyroxine-Binding Proteins / Q000032:analysis*
D013975:Thyroxine-Binding Proteins; D013974:Thyroxine