[Effects of C1-C8 n-alcohols on the growth of 3T3 mouse fibroblasts].
The effect of C1-C8 n-alcohols on 3T3 cell growth is studied using flow cytofluorometry. Methanol and ethanol markedly lengthen either the duration of G1, or that of G2+ M when present in relatively higher doses. The effect of longer chains is always to increase G2+M significantly. This may be due to deviations depending on alcoholic chain length in membrane lipid fluidity.
D000438:Alcohols / Q000494:pharmacology*; D000818:Animals; D002453:Cell Cycle / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects*; D002478:Cells, Cultured; D005347:Fibroblasts / Q000187:drug effects*; D008560:Membrane Fluidity / Q000187:drug effects; D051379:Mice
D000438:Alcohols
Effet des alcools primaires à chaîne saturée de C1 à C8 sur la prolifération des fibroblastes 3T3 de souris.