title: Clinical and histological study to assess changes in the nasal mucosa in patients with chronic perennial rhinitis comparing sodium cromoglycate and placebo.
abstract: A controlled trial comparing sodium cromoglycate 2% nasal solution against placebo has demonstrated that in patients with severe perennial rhinitis sodium cromoglycate is clinically effective and also that gross histological changes in the nasal mucosa are reversed following treatment for eight weeks with this therapy.
mesh_terms: D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004205:Cromolyn Sodium / Q000494:pharmacology* / Q000627:therapeutic use; D004311:Double-Blind Method; D006801:Humans; D009297:Nasal Mucosa / Q000187:drug effects* / Q000473:pathology; D010919:Placebos; D012220:Rhinitis / Q000188:drug therapy*
chemical_list: D010919:Placebos; D004205:Cromolyn Sodium