Increased hepatic glycogen synthetase and decreased phosphorylase in trained rats.
Rats were either physically trained by a 12 wk swimming program or were freely eating or weight matched, sedentary controls. Trained rats had a higher relative liver weight and total hepatic glycogen synthetase (EC 2.4.1.11) activity and a lower phosphorylase (EC 2.4.1.1) activity than the other groups of rats. These changes may partly explain the demonstrated training-induced increase in glucose tolerance. None of the findings could be ascribed to differences in foold intake or body weight.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D005951:Glucose Tolerance Test; D006006:Glycogen Synthase / Q000378:metabolism*; D008099:Liver / Q000201:enzymology* / Q000378:metabolism; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D009929:Organ Size; D006005:Phosphorylases / Q000378:metabolism*; D010805:Physical Conditioning, Animal; D051381:Rats
D001786:Blood Glucose; D008112:Liver Glycogen; D006005:Phosphorylases; D006006:Glycogen Synthase