Hypozincaemia after jejuno-ileal bypass.
Serum zinc, albumin, alpha 2-macroglobulin, calcium, and magnesium were measured in 39 jejuno-ileal shunt-operated patients. The binding of serum zinc to albumin and alpha 2-macroglobulin were calculated. The results demonstrate that the patients as a group had a highly significant hypozincaemia (P less than 0.001), caused by a reduction of the albumin-bound serum zinc (P less than 0.001). Furthermore, the patients showed hypocalcaemia (P less than 0.001) and hypomagnesaemia (P less than 0.001). The findings indicate that patients with jejuno-ileal bypass for gross obesity develop deficiency of the divalent cations.
D000328:Adult; D000510:Alpha-Globulins / Q000032:analysis; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology; D007082:Ileum / Q000601:surgery*; D007583:Jejunum / Q000601:surgery*; D008274:Magnesium / Q000097:blood; D008275:Magnesium Deficiency; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000628:therapy; D011183:Postoperative Complications; D011485:Protein Binding; D012709:Serum Albumin / Q000032:analysis; D015032:Zinc / Q000097:blood* / Q000172:deficiency
D000510:Alpha-Globulins; D012709:Serum Albumin; D008274:Magnesium; D015032:Zinc