Collection of blood from the pituitary stalk and portal veins in monkeys, and from the pituitary sinusoidal system of monkey and man.
A transorbital, transsphenoidal microsurgical approach to the pituitary stalk and gland was used to collect blood from the hypothalamo-hypophyseal portal system in monkeys. Specimens may be obtained from the entire pituitary stalk, individual long portal veins, or the pituitary sinusoidal bed, with little risk of mortality. Continuous stalk blood sampling was carried out for periods of up to 10 hours. Pituitary sinusoidal-system blood was also collected during transsphenoidal surgery in man. The uses of data concerning hypothalamic-hypophyseal regulation obtained by these methods are illustrated.
D000818:Animals; D001800:Blood Specimen Collection / Q000379:methods*; D007987:Gonadotropin-Releasing Hormone / Q000097:blood; D000882:Haplorhini; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008253:Macaca mulatta; D009481:Neurophysins / Q000097:blood; D010902:Pituitary Gland / Q000098:blood supply*; D010906:Pituitary Hormone-Releasing Hormones / Q000097:blood; D013101:Sphenoid Sinus / Q000601:surgery; D014667:Vasopressins / Q000097:blood; D014680:Veins
D009481:Neurophysins; D010906:Pituitary Hormone-Releasing Hormones; D014667:Vasopressins; D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone