Multiple myeloma and chronic lymphatic leukemia in the same patient.
A patient with both chronic lymphatic leukemia and multiple myeloma is presented. Characterisation of the leukemic cells showed them to possess Fc receptors but to lack SmlG and C3 receptors. Intracellular immunoglobulin was not detected within the leukemic cells. The multiple myeloma presented as a soft tissue mass on the chest wall and produced an IgGK paraprotein. The possible relationship of the two disorders is discussed.
D000368:Aged; D006801:Humans; D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D007945:Leukemia, Lymphoid / Q000209:etiology / Q000276:immunology*; D008297:Male; D009101:Multiple Myeloma / Q000209:etiology / Q000276:immunology*; D009378:Neoplasms, Multiple Primary / Q000209:etiology / Q000276:immunology*
D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains