[Calcium utilization in the neuromuscular junction after acetylcholin treatment (author's transl)].
In the site of the myoneural junction a liberation of Ca++ ions, which is similar to that described previously after an electric stimulation or use of cholinesterase inhibitor, can be revealed by histochemical methods (heavy metal substitution, tetracycline fluorescence technique and glyoxal-bis-(2-hydroxyanil) complex formation) using repeated acetylcholine and SCh administration. The possible aspecific reaction due to the presence of Mg++ ions can be excluded by means of the glyoxal-bis(2-hydroxyanil) method. It can be suggested that there is a correlation between the liberation of Ca++ ions an the function dependent mitochondrial energetic processes.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D003964:Diaphragm / Q000187:drug effects* / Q000294:innervation / Q000378:metabolism; D006651:Histocytochemistry / Q000379:methods; D009469:Neuromuscular Junction / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D013390:Succinylcholine / Q000494:pharmacology
D013390:Succinylcholine; D000109:Acetylcholine; D002118:Calcium
Calcium-Freisetzung in der neuromuskulären Junktion auf die Wirkung von Acetylcholin.