Trifluridine in resistant human herpetic keratitis.
Patients with active dendritic herpetic keratitis that was unresponsive to topical idoxuridine or vidarabine therapy were treated topically with a 1% solution of trifluridine. The dendritic ulcers healed in an average time of 6.1 days. All patients tolerated the drug well except for one patient in whom a reversible crystalline epithelial keratitis developed.
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007635:Keratitis, Dendritic / Q000188:drug therapy*; D008297:Male; D013936:Thymidine / Q000031:analogs & derivatives*; D014271:Trifluridine / Q000009:adverse effects / Q000627:therapeutic use*
D014271:Trifluridine; D013936:Thymidine