title: [Comparative study of allergenic fractions extracted from different strains of staphylococci].
abstract: Various methods for obtaining staphylococcus allergens were approbated. Biological activity of the preparation proved to depend on the method of obtaining it determining the chemical compostition of the preparation, and on the properties of the strain used. A method of alkaline extraction and a strain with marked pathogenicity signs (strain 209) can be recommended for the preparation of staphylococcus allergen. Biological activity of the allergen in case of its approbation in the same dose by protein on laboratory animals and patients proved to be the same.
mesh_terms: D000485:Allergens / Q000276:immunology / Q000302:isolation & purification*; D000818:Animals; D003429:Cross Reactions; D006168:Guinea Pigs; D008722:Methods; D009343:Neisseria / Q000276:immunology; D009345:Neisseria meningitidis / Q000276:immunology; D012882:Skin Tests; D013045:Species Specificity; D013210:Staphylococcus / Q000276:immunology*; D013211:Staphylococcus aureus / Q000276:immunology
chemical_list: D000485:Allergens
vernacular_title: Sravnitel'noe izuchenie allergennykh fraktsiĭ, poluchennykh iz razlichnykh shtammov stafilokokkov.