title: Manufacture of antithymocyte globulin (ATGAM) for clinical trials.
abstract: Methods are described for preparing large amounts of horse anti-human thymocyte globulin (ATG, ATGAM; The Upjohn Company) for clinical use. These methods have been used since 1968 to provide material for clinical trials. Characteristics of 40 lots of ATG are summarized.
mesh_terms: D000818:Animals; D000961:Antilymphocyte Serum / Q000032:analysis / Q000592:standards / Q000633:toxicity; D004339:Drug Compounding; D005260:Female; D000882:Haplorhini; D006736:Horses / Q000276:immunology; D006801:Humans; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000961:Antilymphocyte Serum