[Prevention of cardiovascular complications in manifest arteriosclerosis by the use of Micristine].
A long-term clinical trial in micristin-treated patients suffering from organic arterial circulatory disturbances is reported. Problems of therapy monitoring by determination of the ASA level in plasma and of control of platelet aggregation are discussed. Acute cardiovascular complications (myocardial infarction, stroke, acute vascular occlusion, amputation and angiographically demonstrated progression) were observed. The observation time did not suffice to establish statistically significant differences between micristin therapy anticoagulant treatment and basic cardiovascular therapy. The results are suggestive of a more beneficial effect of anticoagulant treatment.
D000244:Adenosine Diphosphate; D000925:Anticoagulants / Q000627:therapeutic use; D001161:Arteriosclerosis / Q000150:complications*; D001241:Aspirin / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects
D000925:Anticoagulants; D000244:Adenosine Diphosphate; D001241:Aspirin
Zur Prophylaxe kardiovaskulärer Komplikationen bei manifester Arteriosklerose mit Micristin.