title: Biological markers of human tumors and monitoring of cancer treatment.
abstract: The development of human tumors is accompanied very often by tumor-associated phenomena such as production of tumor-derived substances, production of certian substances in response to the tumor or immunological reactions. Up to now no of these phenomena can be used as a diagnostic cancer test but biological markers are increasingly used for monitoring progression and regression of human tumors. Basing on a number of own studies the value of the determination of CEA-serum level and urinary excretion of hydroxyprolin, spermidin and putrescin for monitoring the tumor behaviour particularly during cancer chemotherapy is demonstrated.
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood; D001859:Bone Neoplasms / Q000175:diagnosis; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002822:Choriocarcinoma / Q000175:diagnosis; D006063:Chorionic Gonadotropin / Q000032:analysis; D003110:Colonic Neoplasms / Q000175:diagnosis; D005260:Female; D006801:Humans; D006909:Hydroxyproline / Q000652:urine; D009369:Neoplasms / Q000175:diagnosis* / Q000276:immunology; D011247:Pregnancy; D011379:Prognosis; D011700:Putrescine / Q000652:urine; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D002272:Carcinoembryonic Antigen; D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins; D000469:Alkaline Phosphatase; D006909:Hydroxyproline; D011700:Putrescine