The effect of some N solutions for parenteral nutrition on gastric and pancreatic secretion.
In patients without pancreatic disease Aminofusin L forte infused for 1 h did not stimulate gastric or pancreatic secretion. On the other hand, infusion of casein by hydrolysate led to a significant increase in the concentration and total output of HCl. 4 h intravenous infusion of Aminofusin L forte caused a transient but significant rise of the bicarbonate concentration, amylase activity and above all trypsin activity and output. The results show that N solutions used for parenteral protein nutrition influence in a different way both gastric and pancreatic secretion.
D000596:Amino Acids / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D000681:Amylases / Q000378:metabolism; D001639:Bicarbonates / Q000378:metabolism; D002364:Caseins / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D002918:Chymotrypsin / Q000378:metabolism; D005750:Gastric Juice / Q000378:metabolism*; D006801:Humans; D007263:Infusions, Parenteral; D010189:Pancreatic Juice / Q000378:metabolism*; D010288:Parenteral Nutrition; D011492:Protein Hydrolysates; D012633:Secretin; D012636:Secretory Rate / Q000187:drug effects; D014357:Trypsin / Q000378:metabolism
D000596:Amino Acids; D001639:Bicarbonates; D002364:Caseins; D011492:Protein Hydrolysates; D012633:Secretin; D000681:Amylases; D002918:Chymotrypsin; D014357:Trypsin