title: Planning, implementation, and evaluation of a fortification program. Control of vitamin A deficiency in the Philippines.
abstract: In a three-year pilot project in the Philippines, the magnitude of vitamin A deficiency and its clinical manifestation (xerophthalmia) was determined, and three alternate programs for eliminating and preventing it in various ecologic zones were designed and implemented concurrently in separate areas in each ecologic zone. Results were evaluated, and costs and benefits of each program were determined. The results of the fortification program are reported. Monosodium glutamate (MSG) was selected as the ideal carrier was fortified at a level which provided 15,000 I.U. retinol palmitate to the average family each day. Significant increases in serum A, especially for children with more deficient vitamin A status, resulted. The program's economic benefits significantly outweighted the costs, and the MSG fortification program has been expanded to several additional pilot provinces in the Philippines.
mesh_terms: D000293:Adolescent; D001766:Blindness / Q000191:economics; D002648:Child; D002675:Child, Preschool; D003362:Cost-Benefit Analysis; D005069:Evaluation Studies as Topic; D005527:Food, Fortified; D005971:Glutamates; D006801:Humans; D007223:Infant; D008297:Male; D010679:Philippines; D010865:Pilot Projects; D012111:Residence Characteristics; D012959:Socioeconomic Factors; D012970:Sodium Glutamate; D014801:Vitamin A / Q000097:blood / Q000627:therapeutic use*; D014802:Vitamin A Deficiency / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D014985:Xerophthalmia / Q000517:prevention & control
chemical_list: D005971:Glutamates; D014801:Vitamin A; D012970:Sodium Glutamate