title: [About the temperature dependence of the bactericidal effect of some chemical disinfectants (author's transl)].
abstract: In quantitative suspension tests the influence of different temperatures (4 degrees C, 12 degrees C, 22 degrees C, 37 degrees C, +/- 2 degrees) on the bactericidal effect of formalin, phenol, sodium hydroxide peracetic acid with respect to gram-positive and gram-negative test germs (10(8) KBE/ml original culture) was examined. The results showed for formalin, phenol and sodium hydroxide a distinct temperature factor within the range of the germ-dependent, bactericidal limit concentrations. Compared with the temperature of about 22 degrees C which is normally applied in disinfectants tests revealed that at 12 degrees C the action time had at least to be doubled and at 4 degrees C the action time had to be four times as long for the complete killing of the germs. By contrast, with peracetic acid in its minimum effective concentrations (0.015 to 0.06%) a total germ reduction was attained after identical action times (5 minutes) at temperatures ranging between 4 degrees and 37 degrees C. Recommendations for the use of disinfectants must make allowance for the temperature factor.
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D004202:Disinfectants; D005557:Formaldehyde / Q000494:pharmacology; D010463:Peracetic Acid / Q000494:pharmacology; D010545:Peroxides / Q000494:pharmacology; D010636:Phenols / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013045:Species Specificity; D013211:Staphylococcus aureus / Q000187:drug effects; D013291:Streptococcus / Q000187:drug effects; D013696:Temperature
chemical_list: D004202:Disinfectants; D010545:Peroxides; D010636:Phenols; D005557:Formaldehyde; D010463:Peracetic Acid
vernacular_title: Zur Temperaturabhängigkeit der bakteriziden Wirkung einiger chemischer Desinfektionsmittel.