Biological tolerance of copolymers of N-substituted (meth)acrylamides in the test organism.
The mechanical properties of hydrolphilic crosslinked polymers of N-substituted (meth)acrylamides may be improved by copolymerization with N-tertbutylacrylamide [1] so that the mechanical properties of resulting copolymers satisfy requirements on polymers used in medicine. Tests of the biological tolerance of the above copolymers have shown that the latter are completely nontoxic with respect to cell cultures and do not cause any reaction or changes in the subcutaneous implantation into a living organism.
D000178:Acrylamides / Q000138:chemical synthesis / Q000633:toxicity*; D000818:Animals; D002478:Cells, Cultured; D003238:Connective Tissue / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D004343:Drug Implants; D000882:Haplorhini; D007668:Kidney; D051381:Rats; D012867:Skin / Q000187:drug effects
D000178:Acrylamides; D004343:Drug Implants