[The "e" antigen system in HBs antigen carriers (author's transl)].
Antigen e and its antibody were sought by radial immunodiffusion in 86 carriers of HBs antigen observed over a period of one year. The antigen was found in 3 cases out of 30 with acute viral hepatitis, 11 cases out of 33 with chronic active hepatitis, 1 case out of 6 with chronic persistent hepatitis and 1 out of 6 healthy carriers. It was not found in the serum of 6 patients with fulminating hepatitis. The presence of antigen e is associated with high titers of circulating HBs antigens (p less than 0,001). In this group, no difference in the course of the disease was found in cases of chronic active hepatitis with HBs antigen, according to the presence or absence of antigen e or its antibody.
D000208:Acute Disease; D002353:Carrier State / Q000276:immunology; D002908:Chronic Disease; D005500:Follow-Up Studies; D006509:Hepatitis B / Q000276:immunology*; D006510:Hepatitis B Antibodies / Q000032:analysis; D006511:Hepatitis B Antigens / Q000032:analysis*; D006801:Humans; D005779:Immunodiffusion / Q000379:methods
D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens
Système antigénique "e" chez les sujets porteurs de l'antigène HBs.