title: Grand mal-provoked hyperuricemia.
abstract: A significant increase in S-urate was found postictally in 17 patients with two or more grand mal seizures within 24 h. In six patients S-urate was above the level at which hyperuricemic renal failure may develop. Impaired renal function was observed in two patients who had extremely high S-urates. It is proposed that prophylactic procedures against hyperuricemic renal failure should be carried out in all patients with repetitive convulsions.
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D000328:Adult; D000368:Aged; D001219:Aspartate Aminotransferases / Q000097:blood; D003404:Creatinine / Q000652:urine; D004830:Epilepsy, Tonic-Clonic / Q000150:complications / Q000652:urine*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000652:urine; D012964:Sodium / Q000652:urine; D014527:Uric Acid / Q000652:urine*
chemical_list: D014527:Uric Acid; D012964:Sodium; D003404:Creatinine; D001219:Aspartate Aminotransferases; D011188:Potassium