title: Closed needle liver biopsy for assessment of monooxygenase activity in rhesus monkeys (Macaca mulatta).
abstract: Closed needle liver biopsy routinely provides 60-100 mg tissue from rhesus monkeys (Macaca mulatta). No mortality or morbidity was observed in over 400 needle biopsies during a two-year period in which some monkeys were biopsied over 30 times. Biopsy tissue was used as enzyme source in low-volume in vitro systems for measurement of hepatic monooxygenase activity.
mesh_terms: D000818:Animals; D001707:Biopsy, Needle / Q000379:methods / Q000662:veterinary*; D000882:Haplorhini; D008099:Liver / Q000201:enzymology; D008251:Macaca / Q000378:metabolism*; D008253:Macaca mulatta / Q000378:metabolism*; D010105:Oxygenases / Q000378:metabolism*
chemical_list: D010105:Oxygenases