Interference of intravenous lipid emulsion with the determination of calcium in serum.
A lipid emulsion in concentrations similar to those attained after therapeutic dosages were found to interfere with the determination of total serum calcium measured by a fluorometric method. Calcium results determined by atomic absorption and by fluorometry at different concentrations of lipid emulsion were compared. When lipid concentrations were less than 100 mg/dl, centrifugation was effective in eliminating the artifactural elevation in total serum calcium. Possible reasons for the observed differences are discussed.
D002118:Calcium / Q000097:blood*; D005217:Fat Emulsions, Intravenous / Q000032:analysis / Q000494:pharmacology*; D005470:Fluorometry; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D010288:Parenteral Nutrition; D013054:Spectrophotometry, Atomic
D005217:Fat Emulsions, Intravenous; D002118:Calcium