Opposite effects of one and three injections of cortisone or thyroxine on intestinal lactase activity in suckling mice.
A single injection of cortisone or thyroxine to 8-day-old suckling mice initiates a temporary decrease of lactase activity. On the contrary, 3 injections of cortisone or thyroxine provoke a significant increase of lactase activity. It appears that the mechanism which controls the postnatal development of lactase in suckling animals is more complex than expected.
D000828:Animal Population Groups / Q000378:metabolism*; D000818:Animals; D000833:Animals, Suckling / Q000378:metabolism*; D003348:Cortisone / Q000494:pharmacology*; D005696:Galactosidases / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000201:enzymology; D007421:Intestine, Small / Q000201:enzymology*; D051379:Mice; D008871:Microvilli / Q000201:enzymology; D013974:Thyroxine / Q000494:pharmacology*; D001616:beta-Galactosidase / Q000378:metabolism*
D005696:Galactosidases; D001616:beta-Galactosidase; D013974:Thyroxine; D003348:Cortisone