title: Loperamide, a new antidiarrheal agent in the treatment of chronic diarrhea.
abstract: Loperamide is an effective and safe antidiarrheal agent which served as a very useful adjunct in the treatment in 79% of 47 patients with chronic diarrhea. One of the major advantages of loperamide to the patient with chronic diarrhea is its convenience. Usually, a single dose in the morning effectively controlled diarrhea during the day. Patients with nocturnal or early morning diarrhea obtained good control with a second bedtime dose of the drug.
mesh_terms: D000328:Adult; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D003967:Diarrhea / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008134:Long-Term Care; D008139:Loperamide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D010880:Piperidines / Q000627:therapeutic use*; D010919:Placebos
chemical_list: D010880:Piperidines; D010919:Placebos; D008139:Loperamide