Optimization procedures in twin zygosity diagnosis by genetic markers. A cost-effectiveness analysis.
More and more genetic markers usable for twin zygosity determination have become available. A relatively small number of markers is sufficient to achieve a satisfactory probability of correctly classifying a twin pair. Previously only the genetic properties of markers have been considered when choosing the markers to be determined. A cost-effectiveness analysis, which considers both genetic properties and relative determination costs of markers, is presented and illustrated with data from the Finnish Twin Registry studies.
D003362:Cost-Benefit Analysis; D005260:Female; D005819:Genetic Markers; D006801:Humans; D011247:Pregnancy; D014427:Twins
D005819:Genetic Markers