title: The use of antithyroid therapy in the treatment of neoplastic conditions with cytotoxic drugs.
abstract: Taking into account the known actions of thyroid hormone, we suggest that standard antithyroid therapy may be used to create a situation of greater sensitivity to cytotoxic drugs in tumour tissues as compared with normal tissues.
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents; D013956:Antithyroid Agents / Q000627:therapeutic use*; D001853:Bone Marrow / Q000187:drug effects; D004357:Drug Synergism; D004734:Energy Metabolism / Q000187:drug effects; D006801:Humans; D008938:Mitosis / Q000187:drug effects; D009369:Neoplasms / Q000188:drug therapy*; D014176:Protein Biosynthesis; D051381:Rats; D013963:Thyroid Hormones / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D013956:Antithyroid Agents; D013963:Thyroid Hormones