[Dynamics of the appearance and disappearance of S-antigen in cells abortively of lytically infected with OV40 virus].
A highly sensitive mized hemadsorption test and blocking of it were used to study the size of the S-antigen-inducing dose of OV40 virus and the dynamics of the appearance of S-antigen under conditions of abortive and lytic infection. The data on the loss and persistence of this antigen in stationary and multiplying cultures of hamster and monkey cell are presented. S-antigen could be detected in OV40 virus-infected hamster and monkey cells long before their morphological transformation. No antigen was found upon passages of the infected hamster cells but it persisted in non-multiplying infected hamster cells as well as in productivity infected green monkey cells, irrespective of the number of passages, up to the onset cytopathic effect.
D000818:Animals; D000956:Antigens, Viral; D006224:Cricetinae; D046508:Culture Techniques; D003588:Cytopathogenic Effect, Viral; D004263:DNA Tumor Viruses / Q000276:immunology*; D000882:Haplorhini; D006382:Hemadsorption; D006383:Hemadsorption Inhibition Tests
D000956:Antigens, Viral
Dinamika poiavleniia i utraty S-antigena v kletkakh, abortivno ili liticheski infitsirovannykh virusom OV40.