[Chemotherapy of non-microcellular disseminated bronchial cancer (author's transl)].
Fifty-one patients suffering from non-microcellular bronchial cancer with metastasis were divided at random into two groups: 33 patients received BACFON polychemotherapy, 18 patients did not receive chemotherapy. There was no global significant difference between the two groups (total mean survival time : 22 weeks with good therapy and 18 without), but a significant difference could be observed if there was an early response (M.S.T. : 38 weeks) compared to no response (M.S.T. : 15 weeks). Similar results were obtained when radiotherapy was associated (M.S.T. : 34 weeks) compared to chemotherapy without radiotherapy (M.S.T. : 22 weeks).
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy; D000328:Adult; D000368:Aged; D001761:Bleomycin / Q000627:therapeutic use; D001984:Bronchial Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy; D018288:Carcinoma, Small Cell / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008466:Mechlorethamine / Q000627:therapeutic use; D008875:Middle Aged; D009362:Neoplasm Metastasis; D014750:Vincristine / Q000627:therapeutic use
D001761:Bleomycin; D008466:Mechlorethamine; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D005472:Fluorouracil
Chimiothérapie des cancers bronchiques disséminés non microcellulaires.