Combination of radiotherapy and razoxane (ICRF 159) for chondrosarcoma.
Eight patients with 12 chondrosarcomas were treated with radiation and razoxane (ICRF 159). Two tumors in 1 patient progressed unequivocally, 3 tumors in 3 patients showed no change, and 7 tumors in 5 patients had complete or partial (more than 50%) regressions. At least 2 complete regressions have responded for more than 2 1/2 years at the present time.
D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000628:therapy; D002813:Chondrosarcoma / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use*; D011882:Radiotherapy, High-Energy; D011929:Razoxane / Q000627:therapeutic use*; D012075:Remission, Spontaneous; D012983:Soft Tissue Neoplasms / Q000628:therapy; D013997:Time Factors
D010879:Piperazines; D011929:Razoxane