Clinical analgesic assay of oral zomepirac and intramuscular morphine.
Zomepirac appears to be an unexpectedly effective oral, non-opioid analgesic. The relative potency of oral zomepirac is roughly 1/5 to 1/8 that of intramuscular morphine. Visual analogues of pain relief offer a reliable alternative to verbal categorical scales, and may provide some advantages in assays of peak drug effect, and in relatively small patient populations.
D000284:Administration, Oral; D000339:Affect / Q000187:drug effects; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D002908:Chronic Disease; D006801:Humans; D009020:Morphine / Q000009:adverse effects / Q000494:pharmacology*; D010146:Pain / Q000188:drug therapy; D010149:Postoperative Pain / Q000188:drug therapy; D011758:Pyrroles / Q000494:pharmacology*; D012107:Research Design; D014046:Tolmetin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives / Q000494:pharmacology*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011758:Pyrroles; D009020:Morphine; C020549:zomepirac; D014046:Tolmetin