[Modifications in alpha 2 globulins, gamma globulins and in rheumatoid factor during gold salt therapy in rheumatoid arthritis].
A total dose of g 1.071, given as hydrosoluble salts for a 12 month period, showed a significant decrease in serum gamma globulins along with clinical improvement in 17 patients affected with rheumatoid arthritis. A decrease in alpha 2 globulins and in rheumatoid factor titre was observed too, but it was not significant. The data suggest that in rheumatoid arthritis the gold therapy might also be effective on the immunological disease mechanism.
D000328:Adult; D000510:Alpha-Globulins / Q000378:metabolism*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy / Q000276:immunology*; D005260:Female; D006046:Gold / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012217:Rheumatoid Factor / Q000378:metabolism*; D005719:gamma-Globulins / Q000378:metabolism*
D000510:Alpha-Globulins; D005719:gamma-Globulins; D006046:Gold; D012217:Rheumatoid Factor
Modificazioni delle alpha 2 globuline, delle gamma globuline e del fattore reumatoide durante terapia con sali d'oro nell'artrite reumatoide.