Isoniazid inhibition of the synthesis of monounsaturated long-chain fatty acids in Mycobacterium tuberculosis H37Ra.
Isoniazid inhibited C(24) and C(26) monounsaturated fatty acid synthesis in Mycobacterium tuberculosis H37Ra. Time courses of this inhibition and that of mycolic acid synthesis were similar.
D005231:Fatty Acids, Unsaturated / Q000096:biosynthesis*; D007538:Isoniazid / Q000494:pharmacology*; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000378:metabolism; D009171:Mycolic Acids / Q000096:biosynthesis
D005231:Fatty Acids, Unsaturated; D009171:Mycolic Acids; D007538:Isoniazid