Comparison of serum and prostatic levels of tobramycin.
Tobramycin sulfate, an aminoglycoside antibiotic, has been shown to be effective in the treatment of complicated urinary tract infections. Because of this, a study was undertaken to determine the penetrance of tobramycin into the prostate gland. It was found that the drug is concentrated at inhibitory levels in the prostate gland after the routinely recommended administration and should be useful in the treatment of bacterial prostatic infection.
D000900:Anti-Bacterial Agents / Q000378:metabolism*; D006801:Humans; D008297:Male; D011467:Prostate / Q000378:metabolism*; D011511:Proteus / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D014031:Tobramycin / Q000097:blood / Q000378:metabolism* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D014031:Tobramycin