[Transitory burst-suppression pattern in endogenous-exogenous encephalopathy (author's transl)].
A status epilepticus was observed in a 22 year old female patient during endotoxinshock. The status epilepticus was treated with a high dosage of diazepame. The EEG showed a burst suppression pattern, in our case mixed by anoxia and diazepame. The burst-suppression pattern and the clinical suspicion of delayed degradation of diazepame caused by toxic hepatic failure suggested the therapy of forced diuresis. This therapy was followed by decreasing suppression periods, indicating the dominante influence of the hypnotic drug. This result shows the diagnostic as well as the therapeutic value of forced diuresis in this case.
D000328:Adult; D001927:Brain Diseases / Q000139:chemically induced; D002540:Cerebral Cortex; D003975:Diazepam / Q000009:adverse effects / Q000627:therapeutic use*; D004232:Diuretics / Q000627:therapeutic use; D004569:Electroencephalography; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000150:complications*; D008099:Liver / Q000378:metabolism; D012772:Shock, Septic / Q000150:complications*; D013226:Status Epilepticus / Q000188:drug therapy / Q000209:etiology*; D013577:Syndrome
D004232:Diuretics; D003975:Diazepam
Reversibles Burst-suppression-Muster bei einer endogen-exogenen toxischen Enzephalopathie.