Treatment of leishmaniasis recidivens with intralesional injections of emetine hydrochloride: a case report.
A patient, suffering for 42 years from the late tuberculoid-type of leishmaniasis located in his face, was successfully treated with intralesional injections of emetine hydrochloride. Previous treatments, which included intralesional injections of steroids and concomitant intramuscular injections of antimonials, flagyl, fluorocytosine, infusions of amphotericin B--with and without concomitant treatment by steroids systemically and/or intralesionally--and amphotericin B intralesionally, were altogether ineffective. In addition, the patient underwent five operations in a plastic surgery department.
D000328:Adult; D002908:Chronic Disease; D004640:Emetine / Q000008:administration & dosage / Q000627:therapeutic use*; D005148:Facial Dermatoses / Q000188:drug therapy*; D006801:Humans; D007271:Injections, Intradermal; D007896:Leishmaniasis / Q000150:complications / Q000188:drug therapy* / Q000601:surgery; D008297:Male; D011565:Psoriasis / Q000150:complications; D012874:Skin Diseases, Infectious / Q000188:drug therapy*; D013518:Surgery, Plastic
D004640:Emetine