title: Studies on the duration of local anesthesia. Effects of volume and concentration of a local anesthetic solution on the duration of dental infiltration anesthesia.
abstract: In animals and humans the rate of resorption and the duration of the anesthesia have been investigated, using mepivacaine in different concentrations and volumes without addition of a vasoconstrictor. A linear relationship between duration of anesthesia and the logarithm to the concentration of mepivacaine was found.
mesh_terms: D000328:Adult; D000766:Anesthesia, Dental; D000772:Anesthesia, Local; D000818:Animals; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007271:Injections, Intradermal; D008297:Male; D008619:Mepivacaine / Q000008:administration & dosage* / Q000378:metabolism; D013997:Time Factors
chemical_list: D008619:Mepivacaine