Studies on the duration of local anesthesia. Effects of volume and concentration of a local anesthetic solution on the duration of dental infiltration anesthesia.
In animals and humans the rate of resorption and the duration of the anesthesia have been investigated, using mepivacaine in different concentrations and volumes without addition of a vasoconstrictor. A linear relationship between duration of anesthesia and the logarithm to the concentration of mepivacaine was found.
D000328:Adult; D000766:Anesthesia, Dental; D000772:Anesthesia, Local; D000818:Animals; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007271:Injections, Intradermal; D008297:Male; D008619:Mepivacaine / Q000008:administration & dosage* / Q000378:metabolism; D013997:Time Factors
D008619:Mepivacaine