The effect of dextran on the incidence of thrombosis in microvenous Nakayama ring pin anastomoses. Including further studies on the histopathology of Nakayama anastomoses.
Anastomoses of the posterior facial veins in the rabbits neck (diameter appr. 1.5-2.0 mm) were performed under the operating microscope, using the Nakayama ring pin stapler. Immediately before the operation the animals received clinical dextran (mw 70000) or physiological saline intravenously in a double-blind randomized pattern. The total incidence of partial or complete thrombosis in this experiment was low (around 10%). No difference between the two groups were detected. All anastomoses were examined in vivo, under the microscope and histologically. The histological findings are penetrated.
D000818:Animals; D003911:Dextrans / Q000627:therapeutic use*; D004311:Double-Blind Method; D004353:Drug Evaluation, Preclinical; D005260:Female; D008297:Male; D008866:Microsurgery / Q000379:methods*; D011183:Postoperative Complications / Q000517:prevention & control*; D011817:Rabbits; D011897:Random Allocation; D013927:Thrombosis / Q000473:pathology / Q000517:prevention & control*; D014680:Veins / Q000473:pathology / Q000601:surgery*
D003911:Dextrans