Long-term complications in Hunter's syndrome.
This report describes the clinical and investigative findings in a 31-year-old man with Hunter's syndrome, showing evidence of severe multisystem involvement. Papilloedema has been present for at least 8 years with no evidence of progressive visual impairment. His most serious and life-threatening complications are laryngeal oedema and tracheal narrowing, which both compromise his respiratory function and constitute a major anaesthetic risk.
D000328:Adult; D000402:Airway Obstruction / Q000209:etiology; D005500:Follow-Up Studies; D006621:Hip Joint / Q000000981:diagnostic imaging; D006801:Humans; D007592:Joint Diseases / Q000209:etiology; D008297:Male; D016532:Mucopolysaccharidosis II / Q000150:complications* / Q000235:genetics; D010211:Papilledema / Q000209:etiology; D010375:Pedigree; D011859:Radiography; D012129:Respiratory Function Tests