[Evidence of abnormalities in net sodium and potassium fluxes in erythrocytes of patients with essential hypertension].
A new and simple laboratory test for measuring net Na+ and K+ fluxes in Na+-loaded/K+-depleted human erythrocytes was developed and applied to hypertension. Moderate essential hypertension was characterized by a constant increase in net K+ influx; more severe cases showed a drop in net Na+ efflux. Na+ and K+ erythrocyte fluxes were found to be normal in hypertension of renal origin.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001692:Biological Transport; D002648:Child; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*
D012964:Sodium; D011188:Potassium
Mise en évidence d'anomalies des flux nets de sodium et de potassium dans les érythrocytes de sujets atteints d'hypertension artérielle essentielle.