IgM cold-warm hemolysins in infectious mononucleosis.
A patient with infectious mononucleosis and immune hemolytic anemia is described. The hemolysis was mediated by the temporary appearance of both a serum IgM anti-i cold agglutinin and an increase of red blood cell i antigen. The cold agglutinin had a high titer, low thermal amplitude and cold-warm hemolytic activity.
D000328:Adult; D000373:Agglutinins; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications / Q000276:immunology*; D003080:Cold Temperature; D000939:Epitopes; D006460:Hemolysin Proteins / Q000032:analysis*; D006358:Hot Temperature; D006801:Humans; D007048:I Blood-Group System; D007075:Immunoglobulin M / Q000276:immunology*; D007244:Infectious Mononucleosis / Q000150:complications / Q000276:immunology*; D008297:Male
D000373:Agglutinins; D000939:Epitopes; D006460:Hemolysin Proteins; D007048:I Blood-Group System; D007075:Immunoglobulin M