Postheparin-diamine oxidase (histaminase) in anaphylaxis.
The level of plasma postheparin-diamine oxidase was determined in two patients three days after an anaphylactic shock and was controlled four weeks, and also six months later. A decrease of the enzyme levels to about 10% of a control group was found and a slow enzyme increase to about 40% observed six months later. It seems probable that in anaphylaxis a depletion of the enzyme in liver and small intestine occurs as could be shown in animals after heparin load.
D000293:Adolescent; D000368:Aged; D006631:Amine Oxidase (Copper-Containing) / Q000097:blood*; D000707:Anaphylaxis / Q000201:enzymology*; D006493:Heparin / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male
D006493:Heparin; D006631:Amine Oxidase (Copper-Containing)