[Antigenic markers of variable region of mouse myeloma MOPC 21 light chain].
Monospecific antibodies against V-region of the L-chain of the mouse myeloma protein MOPC21 (VK 15 group) were obtained and used for preparation of antibody-immunoadsorbents. By means of the immunoadsorbents the content of normal immunoglobulins with antigenic markers of VK 15 group in the serum of mouse strains BALB/c, CBA and C57BL/6 was determined. The least quantity of the proteins determined by this method was estimated to be 1.4%. If each of K-chains of the variable groups is represented equally in the population of normal immunoglobulins, the number of VK groups and respectively germ-line VK genes should be not less than 70.
D000818:Animals; D001666:Binding Sites, Antibody; D000939:Epitopes; D007135:Immunoglobulin Variable Region; D007145:Immunoglobulin kappa-Chains; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009194:Myeloma Proteins; D009374:Neoplasms, Experimental / Q000276:immunology; D010954:Plasmacytoma / Q000276:immunology
D000939:Epitopes; D007135:Immunoglobulin Variable Region; D007145:Immunoglobulin kappa-Chains; D009194:Myeloma Proteins
Antigennye markery variabel'noĭ oblasti legkoĭ tsepi mielomnogo immunoglobulina myshi MOPC 21.