Haematological and biochemical abnormalities associated with intralipid hyperalimentation.
Haematological and biochemical parameters were monitored in six patients during Intralipid hyperalimentation. A mild anaemia was consistently observed, accompanied by morphological changes in red cells, granulocytes, and platelets. All patients demonstrated an abnormally high percentage of plasma cholesterol in the unesterified form and altered plasma cholesterol esterification, but red cells were not uniformly enriched in cholesterol. These findings stress the need for careful monitoring during Intralipid therapy.
D000328:Adult; D000368:Aged; D000740:Anemia / Q000209:etiology; D001792:Blood Platelets / Q000473:pathology; D002784:Cholesterol / Q000097:blood; D004912:Erythrocytes / Q000473:pathology; D005217:Fat Emulsions, Intravenous / Q000009:adverse effects*; D005260:Female; D006098:Granulocytes / Q000473:pathology; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010288:Parenteral Nutrition
D005217:Fat Emulsions, Intravenous; D006454:Hemoglobins; D002784:Cholesterol