[51Cr]EDTA plasma clearance and endogenous creatinine clearance in advanced renal insufficiency.
Comparison of [51Cr]EDTA plasma clearance corrected for extrarenal elimination with 24 h endogenous creatinine clearance in patients with advanced renal failure showed that the corrected [51Cr]EDTA clearance was lower than creatinine clearance, and thus might be a better approximation to the glomerular filtration rate in uraemic patients. The corrections cannot be used on [51cr]EDTA clearance values below the mean extrarenal clearance, averaging 3.7 ml/min.
D000328:Adult; D000368:Aged; D002860:Chromium Radioisotopes; D003404:Creatinine / Q000378:metabolism*; D004492:Edetic Acid / Q000097:blood*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism*; D008297:Male; D008875:Middle Aged
D002860:Chromium Radioisotopes; D004492:Edetic Acid; D003404:Creatinine