Demonstration of an analogue to human pregnancy zone protein in the African green monkey.
A serum protein in the grivet (Cercopithecus aethiops), immunologically cross-reacting with human pregnancy zone protein (PZP), is found in males as well as in nonpregnant females. The electrophoretic mobility, antigenic cross-reactivity, molecular weight, and carbohydrate structure appear analogous to PZP; however, contrary to the situation in man, exogenous estrogens cause a fall in serum concentration of the protein.
D000818:Animals; D002236:Carbohydrate Conformation; D002521:Cercopithecus / Q000097:blood*; D004054:Diethylstilbestrol / Q000494:pharmacology; D000939:Epitopes; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D000882:Haplorhini; D006801:Humans; D007122:Immunoelectrophoresis; D007123:Immunoelectrophoresis, Two-Dimensional; D008297:Male; D008970:Molecular Weight; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000032:analysis* / Q000276:immunology; D013045:Species Specificity
D000939:Epitopes; D011257:Pregnancy Proteins; D004958:Estradiol; D004054:Diethylstilbestrol