Effects of increasing Mg++ ion concentration on the PKU monitoring assay.
Inaccuracies in a commonly used bacterial inhibition assay for blood phenylalanine levels arise when the Mg++ ion concentration in the assay medium is increased. This has practical implications in the diagnosis and management of phenylketonuria.
D001412:Bacillus subtilis / Q000187:drug effects; D006801:Humans; D008274:Magnesium / Q000494:pharmacology*; D010649:Phenylalanine / Q000097:blood; D010661:Phenylketonurias / Q000175:diagnosis*; D013171:Spores, Bacterial / Q000187:drug effects
D010649:Phenylalanine; D008274:Magnesium