title: Histochemical patterns in human breast tumours.
abstract: Histochemical investigations carried out on 104 breast tumours (10 benign proliferations and 94 carcinomas) showed that breast carcinomas were characterized by various enzymological equipments in relation to tumour differentiation degree, histogenesis, functional stage, site of tumour cells in the carcinomatous islands or cords and to hormonal factors. Tumour cells -- stroma interrelationships study pointed out that high glycolysis (high LDH, NADPH2-TR, NADH2-TR activities) and an intense LEPA-activity of tumour cells seem to be favourable for proliferation and local tumour cells migration.
mesh_terms: D001943:Breast Neoplasms / Q000378:metabolism* / Q000473:pathology; D002952:Citric Acid Cycle; D005260:Female; D006019:Glycolysis; D006651:Histocytochemistry; D006801:Humans; D050356:Lipid Metabolism; D009698:Nucleoproteins / Q000378:metabolism; D010429:Pentoses / Q000378:metabolism
chemical_list: D009698:Nucleoproteins; D010429:Pentoses