Animal models of human cholesterol gallstone disease: a review.
Human cholesterol gallstone disease has been a frequent and serious problem. A number of animal models have been reviewed for comparative study of cholesterol lithogenesis. These models in general have involved (1) decreasing bile salt excretion, (2) increasing dietary cholesterol, or (3) inducing gallbladder infection or stasis.
D000818:Animals; D002415:Cats; D002769:Cholelithiasis / Q000209:etiology; D002779:Cholestasis / Q000150:complications; D002791:Cholesterol, Dietary / Q000009:adverse effects*; D002792:Cholestyramine Resin; D006224:Cricetinae; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D006168:Guinea Pigs; D000882:Haplorhini; D006801:Humans; D008095:Lithocholic Acid; D008297:Male; D011817:Rabbits; D051381:Rats; D012377:Rodentia; D012453:Saimiri; D012589:Sciuridae
D002791:Cholesterol, Dietary; D002792:Cholestyramine Resin; D008095:Lithocholic Acid