Diffuse melanosis and trichochromuria in malignant melanoma.
A previous finding of pronounced excretion of trichochromes in a patient with metastasizing melanoma and diffuse melanosis prompted this study on trichochromes in another patient with these two features. The patient now reported also excreted large amounts of trichochromes. Iit is suggested that diffuse melanosis in metastatic melanoma patients is due to deposition of trichochromes in the tissue.
D000328:Adult; D006801:Humans; D008297:Male; D008545:Melanoma / Q000150:complications / Q000652:urine*; D008548:Melanosis / Q000209:etiology / Q000652:urine*; D010860:Pigments, Biological / Q000652:urine*; D012878:Skin Neoplasms / Q000150:complications / Q000652:urine*; D013843:Thiazines / Q000652:urine*
D010860:Pigments, Biological; D013843:Thiazines