Non-A, non-B hepatitis: a new syndrome in uraemic patients.
One hundred patients on chronic haemodialysis were studied prospectively over one year for evidence of hepatitis and of infection with hepatitis A or B virus. Five patients developed transient elevations of SGPT, accompanied by a consistent pattern of clinical manifestations, including low-grade fever, anorexia, nausea, hepatomegaly, and hypotension during dialysis. None of these patients had a positive test for A or B virus infection. Non-A non-B hepatitis appears to cause a specific syndrome in uraemic patients, and its transmission in a dialysis unit seems unrelated to blood transfusions.
D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D000855:Anorexia / Q000150:complications; D005260:Female; D005334:Fever / Q000150:complications; D006526:Hepatitis C / Q000150:complications*; D006525:Hepatitis, Viral, Human / Q000150:complications*; D006529:Hepatomegaly / Q000150:complications; D006801:Humans; D007022:Hypotension / Q000150:complications; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000150:complications; D006435:Renal Dialysis; D013577:Syndrome; D014511:Uremia / Q000150:complications*
D000410:Alanine Transaminase