title: Mutagenic effects of thioacetamide in Drosophila melanogaster.
abstract: Thioacetamide, which is carcinogenic in mice and rats, has been reported as negative in Ames's test on Salmonella his- with and without liver microsomal fraction (S 9 mix). Tests on Drosophila reported here showed a significant increase in sex-linked recessive lethals after treatment with thioacetamide, both after injection and after feeding of males.
mesh_terms: D000081:Acetamides / Q000494:pharmacology*; D004331:Drosophila melanogaster / Q000235:genetics; D005821:Genetic Techniques; D009153:Mutagens; D012737:Sex Factors; D013853:Thioacetamide / Q000494:pharmacology*
chemical_list: D000081:Acetamides; D009153:Mutagens; D013853:Thioacetamide