[Presence of lectin-like substances in the basement membrane of the human kidney glomerulus].
Crude extracts from the human glomerular basement membranes solubilized by pepsin or bacterial collagenase agglutinate normal or transformed human cells. Cytoagglutination is inhibited by N-acetyl-osamines. These properties are reminiscent of lectins. When agglutinated cells are incubated for an additional 20 hrs. period in minimal serum free medium but in presence of these basement membrane extracts, they attach to the glass and spread out.
D000371:Agglutination / Q000187:drug effects; D000373:Agglutinins / Q000032:analysis*; D001485:Basement Membrane / Q000032:analysis / Q000276:immunology; D006595:Hexosamines / Q000494:pharmacology; D006601:Hexoses / Q000494:pharmacology; D006801:Humans; D007678:Kidney Glomerulus / Q000032:analysis* / Q000276:immunology; D037102:Lectins
D000373:Agglutinins; D006595:Hexosamines; D006601:Hexoses; D037102:Lectins
Présence de substances de type lectine dans la membrane basale du glomérule de rein humain.