The effect of housing and gender on preference for morphine-sucrose solutions in rats.
To determine whether opiate consumption is affected by laboratory housing, individually caged and colony rats were given a choice between water and progressively more palatable morphine-sucrose solutions. The isolated rats drank significantly more of the opiate solution, and females drank significantly more than males. In the experimental phase during which morphine-sucrose solution consumption was greatest, the isolated females drank five times as much, and the isolated males sixteen times as much morphine (mg/kg) as the colony females and males respectively.
D000818:Animals; D002755:Choice Behavior / Q000187:drug effects*; D004327:Drinking Behavior / Q000187:drug effects; D005260:Female; D006799:Housing, Animal; D008297:Male; D009020:Morphine / Q000494:pharmacology*; D051381:Rats; D012737:Sex Factors; D012934:Social Isolation; D013395:Sucrose
D013395:Sucrose; D009020:Morphine