title: Influence of molt cycle and beta-ecdysone on protein synthesis in the chelicerate arthropod, Limulus polyphemus.
abstract: 1. The effect of molt cycle stage and beta-ecdysone on protein synthesis in the horsehoe crab, Limulus polyphemus, was examined. 2. A pronounced decline in protein specific radioactivity after incubation with 14C-leucine was noted in muscle, midgut gland and operculum from postmolt to intermolt to premolt and in gut and gill tissue from intermolt to premolt. 3. beta-Ecdysone injections produced an early stimulation of protein synthesis in the midgut gland followed by strong inhibition within 48 hr. 4. Results are compared with those obtained in mandibulate arthropods.
mesh_terms: D000818:Animals; D004441:Ecdysterone / Q000494:pharmacology*; D006737:Horseshoe Crabs / Q000187:drug effects / Q000502:physiology*; D014176:Protein Biosynthesis; D012313:RNA / Q000096:biosynthesis
chemical_list: D004441:Ecdysterone; D012313:RNA