Identification of an NADH-linked disulfide reductase from Bacillus megaterium specific for disulfides containing pantethine 4',4''-diphosphate moieties.
Bacillus megaterium contains an NADH-linked disulfide reductase that is specific for disulfides containing pantethine 4',4''-diphosphate moieties. This reductase is at its highest level in cells late in sporulation and in dormant spores, and could be involved in the formation and cleavage of coenzyme A-protein disulfides which take place late in sporulation and early in spore germination, respectively.
D001410:Bacillus megaterium / Q000201:enzymology*; D004220:Disulfides; D007700:Kinetics; D009247:NADH, NADPH Oxidoreductases / Q000302:isolation & purification / Q000378:metabolism*; D010204:Pantetheine / Q000031:analogs & derivatives; D013171:Spores, Bacterial / Q000201:enzymology; D013379:Substrate Specificity
D004220:Disulfides; C020631:pantethine 4',4''-diphosphate; D010204:Pantetheine; D009247:NADH, NADPH Oxidoreductases