title: The metabolic and functional effects of thyroid hormone excess in rats.
abstract: Oral administration of thyroid powder for 21 days produces hyperglycemia, hypocholesterolemia, increase of the energetic metabolism ratio and diminishing of the anaerobic metabolism ratio. Prolonged oral administration (30--45 days) induces involution of the thyroid gland, symptoms of an aggravated thyrotoxic hepatosis, hypoglycemia, hypocholesterolemia, a significant increase of the energetic metabolism and of the anaerobic metabolism ratios.
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000096:biosynthesis; D056486:Chemical and Drug Induced Liver Injury; D002784:Cholesterol / Q000097:blood; D004734:Energy Metabolism / Q000187:drug effects*; D006980:Hyperthyroidism / Q000139:chemically induced / Q000378:metabolism / Q000503:physiopathology*; D007773:Lactates / Q000378:metabolism; D008297:Male; D011773:Pyruvates / Q000378:metabolism; D051381:Rats; D013962:Thyroid (USP); D013963:Thyroid Hormones / Q000008:administration & dosage
chemical_list: D001786:Blood Glucose; D007773:Lactates; D011773:Pyruvates; D013962:Thyroid (USP); D013963:Thyroid Hormones; D002784:Cholesterol