[Harmaline-induced tremor and cerebral activities: labeling with 14C-2-deoxyglucose in the rat].
The brain structures specifically involved in harmaline-induced tremor have been identified in the Rat by using the 14C-2-deoxyglucose marking Method. The results obtained in an animal treated with tremogenic doses of harmaline, but immobilized with Faxedil, have been compared with those of another animal, not treated, but submitted to the same experimental procedure. The most specifically marked structure was the inferior olive. Secondarily marked structures were the posterior part of the lateral reticular formation, the caudato-putamen area and the prefrontal and frontal cortex.
D000470:Alkaloids / Q000009:adverse effects*; D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D002250:Carbon Radioisotopes; D002540:Cerebral Cortex / Q000187:drug effects; D003847:Deoxyglucose / Q000378:metabolism; D005625:Frontal Lobe / Q000187:drug effects; D006246:Harmaline / Q000009:adverse effects*; D009847:Olivary Nucleus / Q000166:cytology / Q000187:drug effects; D011699:Putamen / Q000187:drug effects; D051381:Rats; D012154:Reticular Formation / Q000187:drug effects; D014202:Tremor / Q000139:chemically induced*
D000470:Alkaloids; D002250:Carbon Radioisotopes; D003847:Deoxyglucose; D006246:Harmaline
Tremblement harmalinique et activités cérébrales: marquage au 14C-2-désoxyglucose chez le rat.