Facilitating effects of chlordiazepoxide on locomotor activity and avoidance behaviour of reserpinized mice.
Chlordiazepoxide increased the spontaneous locomotor activity of both normal and reserpinized mice and facilitated the avoidance behaviour of mice pretreated with reserpine. These effects of chlorodiazepoxide on reserpinized animals were unexpected, since they are usually considered characteristic of antidepressant drugs.
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D002707:Chlordiazepoxide / Q000494:pharmacology*; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects*; D012110:Reserpine / Q000494:pharmacology; D013268:Stimulation, Chemical; D013997:Time Factors
D002707:Chlordiazepoxide; D012110:Reserpine