A placebo-controlled trial of ketotifen (HC 20-511, Sandoz) in allergen induced asthma and comparison with disodium cromoglycate.
Ketotifen failed to protect against cat fur allergen induced asthma in a double blind placebo-controlled trial in ten asthmatic children. Disodium cromoglycate gave effective protection against the immediate and the late asthmatic reactions but there were no significant differences between the effects of ketotifen and a placebo.
D000293:Adolescent; D000485:Allergens / Q000276:immunology*; D000818:Animals; D001249:Asthma / Q000188:drug therapy*; D002415:Cats; D002648:Child; D002986:Clinical Trials as Topic; D004205:Cromolyn Sodium / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D010366:Peak Expiratory Flow Rate; D010880:Piperidines / Q000627:therapeutic use*; D010919:Placebos; D013876:Thiophenes / Q000627:therapeutic use*; D013997:Time Factors
D000485:Allergens; D010880:Piperidines; D010919:Placebos; D013876:Thiophenes; D004205:Cromolyn Sodium