title: Catabolism of taurine in Pseudomonas aeruginosa.
abstract: Cell-free extracts of taurine-grown Pseudomonas aeruginosa catalyze the transamination of taurine and pyruvate resulting in the formation of L-alanine and sulfoacetaldehyde. The enzyme responsible for this activity has been partially purified in order to demonstrate its participation in a pathway of taurine degradation. Ethyl methane sulfonate treatment of Ps. aeruginosa yielded a mutant deficient in taurine transaminase and incapable of growing on taurine indicating that the enzyme is of physiological significance in this organism.
mesh_terms: D004790:Enzyme Induction; D005020:Ethyl Methanesulfonate / Q000494:pharmacology; D009154:Mutation; D011550:Pseudomonas aeruginosa / Q000235:genetics / Q000378:metabolism*; D011773:Pyruvates; D013654:Taurine / Q000378:metabolism*; D000637:Transaminases / Q000096:biosynthesis / Q000378:metabolism*
chemical_list: D011773:Pyruvates; D013654:Taurine; D005020:Ethyl Methanesulfonate; D000637:Transaminases