Drug-modulated behavioural responses to environmental enrichment.
The home-cage activity of mice housed in either social or enriched sensory environments was continuously recorded for 23 days. During this period the mice were given daily injections of either strychnine, chlorpromazine, or saline. Both chlorpromazine and social rearing depressed home-cage activity. Strychnine also depressed activity, but only in the social group.
D000818:Animals; D001143:Arousal / Q000187:drug effects; D002746:Chlorpromazine / Q000494:pharmacology; D002940:Circadian Rhythm; D004777:Environment; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects*; D012931:Social Environment; D013331:Strychnine / Q000494:pharmacology; D013997:Time Factors
D013331:Strychnine; D002746:Chlorpromazine