Inhibitory effect of charcoal-treated porcine follicular fluid upon serum FSH levels and follicular development in the rhesus monkey.
Injection of charcoal treated porcine follicular fluid into 4 intact, 4 long term castrate and 2 postmenopausal rhesus monkeys brought about a selective decline in serum FSH levels. Luteinizing hormone levels were not significantly decreased. Intraperitoneal injection of 4 ml porcine follicular fluid every 8 hours for the first 4 days of the menstrual cycle led to a decrease in follicle and granulosa cell growth observed at that midcycle. Treatment with porcine serum did not exert this effect.
D000818:Animals; D002369:Castration; D002606:Charcoal; D005110:Extracellular Space / Q000502:physiology; D005260:Female; D005640:Follicle Stimulating Hormone / Q000037:antagonists & inhibitors / Q000097:blood*; D000882:Haplorhini; D008593:Menopause; D008598:Menstruation; D006080:Ovarian Follicle / Q000254:growth & development / Q000502:physiology*; D010455:Peptides / Q000494:pharmacology; D013552:Swine
D010455:Peptides; D002606:Charcoal; D005640:Follicle Stimulating Hormone