[Gram-positive bacteria as adjuvants (author's transl)].
Gram-positive bacteria or their constituents influence the immune response in various ways. For instance: Listeria monocytogenes cellwall fraction acts as B-cell mitogen, in this way enhancing a humoral immune response. Corynebacterium parvum acts as a macrophage stimulant evoking maximum macrophage activation. BCG, among other things, leads to an enhancement of a T-cell response to unrelated antigens. The hypothetical therapeutic consequences are discussed.
D000276:Adjuvants, Immunologic; D001402:B-Lymphocytes / Q000276:immunology; D001500:BCG Vaccine; D001419:Bacteria / Q000276:immunology*; D008089:Listeria monocytogenes / Q000276:immunology; D008213:Lymphocyte Activation; D008264:Macrophages / Q000276:immunology; D008934:Mitogens; D009163:Mycobacterium bovis / Q000276:immunology; D011425:Propionibacterium acnes / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D000276:Adjuvants, Immunologic; D001500:BCG Vaccine; D008934:Mitogens
Grampositive Bakterien als Adjuvanzien.