[Additional tocolysis via inhibition of prostaglandin synthetase with indometacin (author's transl)].
Indometacin was administered as additional tocolyticum in 42 women between the 27. and 36. week of pregnancy. Patients received indometacin oral, of a complete tocolysis could not be achieved by application of beta-sympathicomimetica. A complete tocolysis always could be achieved with a daily dose of 200 mg indometacin. The mean time of therapy was 7,5 days, the mean total dose 1100 mg.
D002986:Clinical Trials as Topic; D016861:Cyclooxygenase Inhibitors; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000494:pharmacology / Q000627:therapeutic use*; D007752:Obstetric Labor, Premature / Q000517:prevention & control*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D013566:Sympathomimetics / Q000627:therapeutic use; D014590:Uterine Contraction / Q000187:drug effects*
D016861:Cyclooxygenase Inhibitors; D013566:Sympathomimetics; D007213:Indomethacin
Zusatztokolyse durch Prostaglandinsythetasehemmung mit Indometacin.