[Genetic limitations of erythrocyte lysis by bacteria of the genus Salmonella].
Lytic effect of Salmonella bacteria on the erythrocates of 1301 humans (including 150 twins), 1059 hens, 600 mice, 33 guinea pigs, 47 rabbits, 22 horses, 16 sheeps, 7 dogs, 2 cats and 2 monkeys was investigated. Erythrocytes of all horses, guinea pigs and rabbits tested appeared to be sensible. The same cells of humans, sheeps, hens, dogs, monkeys and cats turned to be either sensible, or stable. Human erythrocytes were the most stable. Erythrocytes of humans having had typhus or other Salmonella infections appeared to be more sensible. Homozygous twins developed complete two by two concordance of the sign of sensibility in all details investigated. Relation of erythrocytes to Salmonella hemolysins was not influences with time and specific immunization, did not correlate with blood groups and factors ABO, MN, P and rhesis systems, with age, sex and nationality of people tested. It also did not correlate with the presence of anti-salmonella agglutinins, with different osmotic and acid stability of erythrocytes. The display of hemolytic activity of Salmonella is limited by genetically predestinated species and individual properties of erythrocytes.
D000818:Animals; D002415:Cats; D002645:Chickens; D004285:Dogs; D004912:Erythrocytes / Q000187:drug effects*; D005260:Female; D005838:Genotype; D006168:Guinea Pigs; D000882:Haplorhini; D006460:Hemolysin Proteins / Q000494:pharmacology; D006461:Hemolysis / Q000187:drug effects*; D006736:Horses; D006801:Humans; D008251:Macaca; D051379:Mice; D011247:Pregnancy; D011817:Rabbits; D012475:Salmonella / Q000472:pathogenicity*; D012756:Sheep; D013045:Species Specificity; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic; D014586:USSR
D006460:Hemolysin Proteins
Geneticheskie ogranicheniia lizisa éritrotsitov bakteriiami roda Salmonella.