[Respective position of antidepressants in therapeutics (author's transl)].
The author points out the heterogeneity of depressions and antidepressants. He stresses the need of finding predictive indicators of antidepressant activity. Genetic, "demographic", biological, biochemical and pharmacokinetic factors can help to guide antidepressant's prescription. Urinary MHPG dosage seems to be one of the most interesting in this field.
D000928:Antidepressive Agents / Q000627:therapeutic use*; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D002394:Catechol O-Methyltransferase / Q000097:blood; D003863:Depression / Q000188:drug therapy* / Q000201:enzymology / Q000209:etiology; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid; D008734:Methoxyhydroxyphenylglycol / Q000652:urine; D008995:Monoamine Oxidase / Q000097:blood
D000928:Antidepressive Agents; D000929:Antidepressive Agents, Tricyclic; D008734:Methoxyhydroxyphenylglycol; D006897:Hydroxyindoleacetic Acid; D008995:Monoamine Oxidase; D002394:Catechol O-Methyltransferase
Place respective des différents antidépresseurs en thérapeutique.