Preliminary observations on the potential of 99mTc-sulfur colloid as a radiopharmaceutical for detection of deep vein thrombosis.
The potential usefulness of 99mTc-sulfur colloid (Tc-SC) as a radiopharmaceutical for thrombus detection was evaluated in an animal model of deep vein thrombosis. One hour after injection of Tc-SC and 24 hours after induction of thrombus formation, a mean thrombus-to-blood uptake ratio of 11.38 was obtained in 12 beagles. This ratio is high enough to allow external detection.
D000818:Animals; D003102:Colloids; D004285:Dogs; D005268:Femoral Vein; D000882:Haplorhini; D011877:Radionuclide Imaging; D013455:Sulfur; D013667:Technetium; D013927:Thrombosis / Q000000981:diagnostic imaging*
D003102:Colloids; D013455:Sulfur; D013667:Technetium