On the process of activation and inactivation of dog skeletal muscle glycogen synthase.
The presence of additional forms of glycogen synthase (UDPG: alpha-1,4-glucan alpha-4-glucosyltransferase) besides the I form (independent on glucose-6-P for activity) and the D form (dependent on glucose-6-P for activity) long ago described, is inferred from patterns of their interconversions obtained by processes of phosphorylation and dephosphorylation. An intermediate form more phosphorylated than the I form and less than the D form, which is completely inactive in these assay conditions, and a superphosphorylated form, more phosphorylated than the D form and also inactive even in presence of 0.01 M glucose-6-P are described.
D000818:Animals; D004285:Dogs; D004789:Enzyme Activation; D004794:Enzyme Repression; D006006:Glycogen Synthase / Q000378:metabolism*; D007866:Leg / Q000201:enzymology; D009132:Muscles / Q000201:enzymology*; D010766:Phosphorylation; D010770:Phosphotransferases / Q000378:metabolism*
D006006:Glycogen Synthase; D010770:Phosphotransferases