Mutagenic activity of selenium compounds.
The mutagenicities of selenate (SeO2/4-) and selenite (SeO2/3-) were determined by two bacterial assay systems: Kada's rec-assay and Ames's Salmonella test. In both assays, these compounds were found to be weak mutagens. In the Salmonella test, selenate (0.05 revertants/nmole) and selenite (0.2 revertants/nmole) gave rise to base-pair substitution.
D001412:Bacillus subtilis / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D009153:Mutagens; D009154:Mutation; D012486:Salmonella typhimurium / Q000187:drug effects; D012643:Selenium / Q000494:pharmacology*
D009153:Mutagens; D012643:Selenium