[Evolution and transformation in animal organism of some polychlorobiphenyls (author's transl)].
Intoxication by pure polychlorobiphenyls and a commercial product is studied, in rats, after intraperitoneal and oral administration. Their fixation and excretion of their metabolites is greater by intraperitoneal than by oral administration. The only hydroxy metabolites, identified by means of synthesis, gas chromatography and mass spectrometry are, all, derivatives from trichlorobiphenyl. It appears that administration of commercial product induces a more rapid degradation of these compounds in animal organism.
D000284:Administration, Oral; D000818:Animals; D001673:Biodegradation, Environmental; D001711:Biotransformation; D006900:Hydroxylation; D007274:Injections, Intraperitoneal; D007536:Isomerism; D008297:Male; D011078:Polychlorinated Biphenyls / Q000008:administration & dosage / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D011078:Polychlorinated Biphenyls
Evolution et transformation dans l'organisme animal de quelques polychlorobiphényles à l'état pur. Contribution à l'étude d'un produit commercial.