A method for surgical management of focal epilepsy, especially as it relates to children.
A method of surgical management for intractable epilepsy is described. The essential features are: 1) all surgical manipulation is carried out under general, rather than local, anesthesia; 2) the sensorimotor region is readily identified in the anesthetized patient by recording cortical sensory evoked responses; and 3) the epileptogenic focus is localized by extraoperative electrocorticography via indwelling epidural electrode arrays, localization deriving from recordings made during spontaneously occuring clinical seizures. Cases are presented to demonstrate that: 1) in some instances, recording of sensory evoked responses is the only means of sensorimotor localization in both the awake and anesthetized patient, and 2) spontaneous and electrically induced electroencephalographic seizure activity may provide false localization of the focus, the correct localization requiring recordings made during spontaneous clinical seizures. The outcome of surgery and the various epileptogenic lesions encountered are described. A good result has been achieved in 61% of patients followed 1 to 10 years. When the results obtained in children are analyzed alone, 70% have benefited from surgery.
D000293:Adolescent; D000328:Adult; D002540:Cerebral Cortex / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D003949:Diagnostic Techniques, Surgical / Q000379:methods; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000379:methods*; D004828:Epilepsies, Partial / Q000601:surgery*; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D009044:Motor Cortex / Q000503:physiopathology