[The heterogeneity of streptokinases].
Purified streptokinases of some strains of different types of Strep. pyrogenes (group A) as well as streptokinases of a strain of group C or group G streptococci, resp., were studied in regard of their heterogeneity. Differences of the streptokinases were found in their amino acid compositions and in isoelectric points. Serological differences were detected by a quantitative precipitation reaction with fluorescein-coupled antistreptokinase antisera from the goat as well as by neutralization reactions of the activator activities of the streptokinases by antistreptokinase antisera obtained from guinea pigs.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D003429:Cross Reactions; D006041:Goats / Q000276:immunology; D007526:Isoelectric Point; D009500:Neutralization Tests; D011233:Precipitin Tests; D013291:Streptococcus / Q000201:enzymology*; D013297:Streptococcus pyogenes / Q000201:enzymology; D013300:Streptokinase / Q000302:isolation & purification*
D000596:Amino Acids; D013300:Streptokinase
Zur Heterogenität von Streptokinasen.