[Determination of the ribonuclease activity of the duodenal contents of children as a test in the differential diagnosis of cystic fibrosis and pancreatic exocrine insufficiency].
Ribonuclease activity was determined in the duodenal contents of healthy children, in children with cystic fibrosis and with pancreatic exocrine insufficiency. Assays were made at 7.0, in 0.05 M buffer without and with 0.35 M NaCl. The ratio of activity in 0.35 M NaCl to that in buffer alone was found to be 2.4 +/- 1.3 for children with cystic fibrosis as compared with 12 +/- 5 for the control group and children with pancreatic exocrine insufficiency.
D000681:Amylases / Q000172:deficiency; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000175:diagnosis* / Q000201:enzymology; D003937:Diagnosis, Differential; D004386:Duodenum / Q000201:enzymology*; D010188:Exocrine Pancreatic Insufficiency / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D008049:Lipase / Q000172:deficiency; D010179:Pancreas / Q000201:enzymology; D012260:Ribonucleases / Q000032:analysis* / Q000172:deficiency; D014357:Trypsin / Q000172:deficiency
D012260:Ribonucleases; D008049:Lipase; D000681:Amylases; D014357:Trypsin
Oznaczanie aktywności rybonukleazy w treści dwunastniczej u dzieci jako test róznicujacy cystic fibrosis od niewydolności zewna trzwydzielniczej trzustki.