Bacterial utilization of cyclo(glycl-L-prolyl).
3 strains of soil bacteria (2 Achromobacter, 1 Flavobacterium) were isolated by growth on cyclo(Gly-L-Pro) as carbon/nitrogen source. Good growth required yeast extract supplements. Utilization of cyclo(Gly-L-Pro) was inducible. Many efforts failed to obtain active cell-free preparations. Injected radioactive cyclo(Gly-L-Pro) was excreted intact by the albino rat; in contrast, injected radioactive H-Gly-L-Pro-OH was extensively metabolized.
D004151:Dipeptides / Q000378:metabolism*; D005417:Flavobacterium / Q000378:metabolism*; D006088:Gram-Negative Aerobic Bacteria / Q000378:metabolism*; D010456:Peptides, Cyclic / Q000378:metabolism*
D004151:Dipeptides; D010456:Peptides, Cyclic