title: ["First" and "second" generation sulfonylureas: distinction or difference? (author's transl)].
mesh_terms: D000818:Animals; D002747:Chlorpropamide / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005913:Glipizide / Q000494:pharmacology; D005905:Glyburide / Q000494:pharmacology; D006207:Half-Life; D006801:Humans; D007004:Hypoglycemic Agents; D007700:Kinetics; D013329:Structure-Activity Relationship; D013453:Sulfonylurea Compounds / Q000145:classification / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D014044:Tolbutamide / Q000494:pharmacology
chemical_list: D007004:Hypoglycemic Agents; D013453:Sulfonylurea Compounds; D014044:Tolbutamide; D005905:Glyburide; D002747:Chlorpropamide; D005913:Glipizide
vernacular_title: Les sulfonylurées hypoglycémiantes: un problème de générations? Considérations pharmacocinétiques et pharmacodynamiques.