title: Operant control of single neurons in monkey motor cortex.
abstract: This article reviews three points. Monkeys may be trained by operant conditioning to control the firing rate and pattern of single neurons in the precentral cortex. Recent data provide an explanation of how this control is mediated and an accounting of various factors that influence it. Using this technique to study cortical physiology, researchers have generated new insights into the pathophysiology and clinical effects of epilepsy.
mesh_terms: D000818:Animals; D001676:Biofeedback, Psychology; D003216:Conditioning, Operant / Q000502:physiology*; D004576:Electromyography; D005071:Evoked Potentials; D000882:Haplorhini; D009044:Motor Cortex / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D011712:Pyramidal Tracts / Q000502:physiology