Plaque-forming cells in mice after experimental infection with Brucella abortus.
Cells producing antibody to brucella lipopolysaccharide were detected in spleens of mice infected with Brucella abortus 19 by a hemolytic plaque assay. The appearance of immunoglobulin M-producing cells preceded humoral antibodies. The primary plaques were observed 5 days after inoculation, and they were still present by day 70.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000921:Antibody-Producing Cells; D002003:Brucella abortus / Q000276:immunology; D002006:Brucellosis / Q000276:immunology*; D006462:Hemolytic Plaque Technique; D008070:Lipopolysaccharides / Q000276:immunology; D051379:Mice; D013154:Spleen / Q000276:immunology
D000907:Antibodies, Bacterial; D008070:Lipopolysaccharides