Effects of entrapment in liposomes on the distribution, degradation and effectiveness of methotrexate in vivo.
D000818:Animals; D006168:Guinea Pigs; D000882:Haplorhini; D007700:Kinetics; D007939:Leukemia L1210 / Q000188:drug therapy; D008081:Liposomes / Q000627:therapeutic use*; D008099:Liver / Q000378:metabolism; D008252:Macaca fascicularis; D008657:Metabolic Clearance Rate; D008727:Methotrexate / Q000008:administration & dosage* / Q000378:metabolism; D014677:Pharmaceutical Vehicles; D013154:Spleen / Q000378:metabolism; D014018:Tissue Distribution
D008081:Liposomes; D014677:Pharmaceutical Vehicles; D008727:Methotrexate