[Study of a correlation between glycolipids and tumorigenesis in 6 cell lines derived from human brain tumors].
By silica gel chromatography we have studied the various glycolipids of six established lines derived from human brain tumors. Among the glycolipids, the GM3 ganglioside appeared as one of the major components in the three lines rejected by athymic nude Mice. On the contrary, GM3 was absent, or present in trace, in the three tumorigenic lines.
D000818:Animals; D001932:Brain Neoplasms / Q000032:analysis; D002460:Cell Line; D002850:Chromatography, Gel / Q000379:methods; D005679:G(M3) Ganglioside / Q000302:isolation & purification / Q000502:physiology; D006017:Glycolipids / Q000032:analysis*; D006084:Graft Rejection; D006801:Humans; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D014183:Transplantation, Heterologous
D005679:G(M3) Ganglioside; D006017:Glycolipids
Recherche d'une corrélation entre glycolipides et tumorigénicité dans six lignées cellulaires dérivées de tumeurs cérébrales humaines.