title: Evolutionary considerations of DNA repair in relation to mutagenesis, teratogenesis and carcinogenesis.
abstract: Living organisms have various mechanisms for repairing spontaneous and mutagen-induced damage in DNA. Mutagenesis, teratogenesis, and carcinogenesis are discussed in relation to DNA misrepair. The existence of highly efficient genetic mechanisms for tolerating environmental threats is argued from evolutionary viewpoints.
mesh_terms: D000818:Animals; D001412:Bacillus subtilis / Q000528:radiation effects; D005075:Biological Evolution; D002273:Carcinogens; D004260:DNA Repair; D004330:Drosophila; D004926:Escherichia coli / Q000528:radiation effects; D009154:Mutation / Q000528:radiation effects; D013723:Teratogens; D014466:Ultraviolet Rays
chemical_list: D002273:Carcinogens; D013723:Teratogens