[Bartter's syndrome: the long term effects of indomethacin on growth (author's transl)].
Six children with Bartter's syndrome aged 6 years 4 months to 13 years 11 months were treated with indomethacin (1.7 to 4.3 mg/kg/day) during 7 to 27 months. A catch up growth was first observed, then growth curve was parallel to the normal. A catch up weight was also observed. The osseous maturation was the faster it was more delayed. These changes were observed despite a partial correction of potassium and plasma renine activity.
D000293:Adolescent; D000450:Aldosterone / Q000097:blood; D001477:Bartter Syndrome / Q000188:drug therapy*; D001827:Body Height / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D001846:Bone Development / Q000187:drug effects; D002648:Child; D016861:Cyclooxygenase Inhibitors; D004361:Drug Tolerance; D005260:Female; D006130:Growth Disorders / Q000188:drug therapy*; D006801:Humans; D006929:Hyperaldosteronism / Q000188:drug therapy*; D007213:Indomethacin / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D011188:Potassium / Q000097:blood; D011627:Puberty / Q000187:drug effects; D012083:Renin / Q000097:blood; D013997:Time Factors
D016861:Cyclooxygenase Inhibitors; D000450:Aldosterone; D012083:Renin; D011188:Potassium; D007213:Indomethacin
Syndrome de Bartter: effets á long terme de l'indométacine sur la croissance.