title: The response of the living organism to dead and fixed dead enclosed homologous tissue.
abstract: Polyethylene tubes at both ends and with four perforations in the side walls were filled with untreated homologous necrotic muscle tissue or formaldehyde-fixed or glutaraldehyde-fixed homologous necrotic tissue and implanted subcutaneously in rats. The cell reaction in the tissues surrounding the differently filled tubes was examined. It was found that the inflammatory reaction to untreated necrotic homologous tissue was the least severe.
mesh_terms: D000447:Aldehydes / Q000494:pharmacology*; D000818:Animals; D003238:Connective Tissue / Q000033:anatomy & histology; D062109:Dermatologic Surgical Procedures; D005347:Fibroblasts / Q000166:cytology; D005404:Fixatives / Q000494:pharmacology*; D005557:Formaldehyde / Q000494:pharmacology*; D005976:Glutaral / Q000494:pharmacology*; D006098:Granulocytes / Q000166:cytology; D008214:Lymphocytes / Q000166:cytology; D008264:Macrophages / Q000166:cytology; D009132:Muscles / Q000187:drug effects / Q000276:immunology / Q000503:physiopathology* / Q000637:transplantation; D009336:Necrosis / Q000503:physiopathology; D051381:Rats; D012867:Skin / Q000033:anatomy & histology / Q000276:immunology; D012879:Skin Physiological Phenomena; D014184:Transplantation, Homologous; D014945:Wound Healing
chemical_list: D000447:Aldehydes; D005404:Fixatives; D005557:Formaldehyde; D005976:Glutaral