title: Actinomycosis of the larynx and pharynx.
abstract: This paper presents a case report of a 67-year-old man who was seen in the Otolaryngology Clinic, University of Wisconsin Medical Center with a seven-month history of dyspnea and laryngeal stridor. On examination there were several slightly tender firm submucosal nodules in the soft palate and left tonsilar area and a 1.5-cm polypoid subglottic mass arising from the body of the cricoid cartilage. Because of the marked airway obstruction, a tracheotomy was necessary. The laryngeal polypoid mass was removed and biopsies were obtained from the submucosal nodular masses of the palate. Microscopic examination of the tissue revealed the lesions to be caseating granulomas, and actinomycosis was identified on the cultures. The patient received long-term penicillin therapy and has remained asymptomatic. A discussion of the biologic and clinical aspects of actinomycosis is included. A review of the literature revealed only one other description of endolaryngeal actinomycosis.
mesh_terms: D000196:Actinomycosis / Q000175:diagnosis* / Q000382:microbiology; D000368:Aged; D006801:Humans; D007818:Laryngeal Diseases / Q000175:diagnosis* / Q000382:microbiology; D008297:Male; D010608:Pharyngeal Diseases / Q000175:diagnosis* / Q000382:microbiology