title: Genetic and biochemical aspects of sucrase from Drosophila melanogaster.
abstract: Isoelectrofocusing of abdominal extracts of Drosophila melanogaster revealed the existence of two forms of sucrase (E.C. 3.2.1.26). One form exhibited an isoelectric point of 4.63 +/- 0.02 while the other form exhibited an isoelectric point of 4.83 +/- 0.02. The localization of the structural gene for sucrase is proposed on the basis of enzyme determinations in a series of duplication- and deletion-bearing aneuploids. We suggest that the sucrase structural gene lies between 31CD and 31EF on the left arm of chromosome 2 and that the two forms of abdominal sucrase derive from a common protein coded for by a single sucrase gene designated Sucr+.
mesh_terms: D000818:Animals; D003433:Crosses, Genetic; D004261:DNA Replication; D004331:Drosophila melanogaster / Q000235:genetics*; D005796:Genes; D007525:Isoelectric Focusing; D013393:Sucrase / Q000235:genetics* / Q000378:metabolism
chemical_list: D013393:Sucrase