[Diagnosis of hyperprolactinaemias: respective value of response to THR and to bromocriptine (author's transl)].
Seventy tests of stimulation with hypothalamic thyreotrophic hormone liberation factor, and 35 bromocriptine inhibition tests were carried out on a routine basis in patients with latent or frank hyperprolactinaemia. Pathological hyperprolactinaemia does not have a single clinical pattern: frank, it takes the form either of an exteriorised pituitary adenoma (14 cases), or of an amenorrhoea-galactorrhoea syndrome with or without micro-adenoma (12 cases); latent, it takes the form either of isolated amenorrhoea (17 cases) or of dysovulatory sterility (16 cases). Amongst the dynamic tests available, it is worthwhile to make a choice, and in the case of frank hyperprolactinaemia, the authors propose use of the bromocriptine inhibition test in the first instance. The TRH test is reserved for verification of the results of neurosurgery. As far as latent hyperprolactinaemia is concerned, it may be identify only by the TRH test, with the resultant possibility of specific treatment.
D000236:Adenoma / Q000175:diagnosis; D000568:Amenorrhea / Q000175:diagnosis; D001971:Bromocriptine; D005260:Female; D005687:Galactorrhea / Q000175:diagnosis; D006801:Humans; D007247:Infertility, Female / Q000175:diagnosis; D010900:Pituitary Diseases / Q000175:diagnosis*; D010911:Pituitary Neoplasms / Q000175:diagnosis; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*; D013973:Thyrotropin-Releasing Hormone
D001971:Bromocriptine; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin
Diagnostic des hyperprolactinémies: valeur respective du test de stimulation à la T.R.H. et du test de freinage à la bromocriptine.