[Comparison by isoelectrofocusing between blood immunoglobulin G of the mother and her newborn. Value of the method (author's transl)].
The present investigation deals with the study about immunoglobulins in blood of twenty six couples mother-newborn. The immunoglobulins G were determinated by radial immunodiffusion and we stated the profile of serum's proteins after isoelectrofocusing. The results obtained from this study, showed a really important percentage of very differents profiles between mother and newborn's proteins. These divergences are independently from the level of immunoglobulins. The purpose of this investigation is to show the very high analytical power of the method. But it is limited in interpretation of results. With conventional protein procedures, it is not possible to say if the newborn is able to synthetize immunoglobulins very early in life. On the contrary, with specific methods of revelation, isoelectrofocusing seems the better procedure of investigation for identity immunoglobulins in blood.
D004396:Coloring Agents; D005260:Female; D006801:Humans; D005779:Immunodiffusion; D007074:Immunoglobulin G / Q000032:analysis; D007231:Infant, Newborn; D007525:Isoelectric Focusing / Q000379:methods; D008431:Maternal-Fetal Exchange; D011247:Pregnancy
D004396:Coloring Agents; D007074:Immunoglobulin G
Comparaison des tracés d'isoélectrofocalisation en plaque des sérums de mère et de nouveau-né au niveau des immunoglobulines. Valeur de la méthode.