Identification, quantification, and significance of bacterial growth within the biliary tract after Kasai's operation.
Cholangitis is a universal complication of successful hepatic portoenterostomy for biliary atresia. In this study 283 bacteriologic cultures were obtained from 19 patients during a 23-mo period. All bilioenteric conduits were colonized with colonic flora by 1 mo after operation. Cholangitis was characterized by fever and a decrease in bilirubin clearance, but not by a change in the number of different types of bacteria nor a change in the total bacteriologic concentration within the conduit. No overall antibiotic effect on the flora could be found. Cholangitis remains a condition that is necessarily treated empirically.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000302:isolation & purification; D001646:Bile / Q000382:microbiology*; D001659:Biliary Tract / Q000002:abnormalities* / Q000382:microbiology; D001662:Biliary Tract Surgical Procedures; D001663:Bilirubin / Q000032:analysis; D002761:Cholangitis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D004386:Duodenum / Q000601:surgery; D006801:Humans; D011183:Postoperative Complications
D000900:Anti-Bacterial Agents; D001663:Bilirubin