Inhibition of benzo(a)pyrene and benzo(a)pyrene 7,8-dihydrodiol metabolism by benzo(a)pyrene quinones.
D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism* / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004247:DNA / Q000378:metabolism; D004101:Dihydroxydihydrobenzopyrenes; D066298:In Vitro Techniques; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009251:NADPH-Ferrihemoprotein Reductase / Q000378:metabolism; D010101:Oxygen Consumption; D011808:Quinone Reductases / Q000378:metabolism; D011809:Quinones / Q000378:metabolism / Q000494:pharmacology; D051381:Rats; D014535:Uridine Diphosphate Glucuronic Acid / Q000494:pharmacology
D001580:Benzopyrenes; D004101:Dihydroxydihydrobenzopyrenes; D011809:Quinones; C017228:benzo(a)pyrene 7,8-dihydrodiol; D014535:Uridine Diphosphate Glucuronic Acid; D008748:Methylcholanthrene; D004247:DNA; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D009251:NADPH-Ferrihemoprotein Reductase; D011808:Quinone Reductases