title: The metabolism of S-carboxymethylcysteine in rodents, marmosets and humans.
abstract: 1. The metabolism of S-carboxymethylcysteine (Mucodyne) has been studied in the rat, rabbit, guinea-pig, marmoset and human. All species studied, except the rabbit, excrete large amounts of the parent compound. 2. Rabbits and humans give S-carboxymethylcysteine sulphoxide, rats form N-acetyl-S-carboxymethylcysteine while marmosets excrete methylmercapturic acid as other major metabolites. Traces of methylmercapturic acid sulphoxide, methylcysteine, methylcysteine sulphoxide and 3-(S-carboxymethylthio)lactic acid were also found.
mesh_terms: D000328:Adult; D000818:Animals; D001711:Biotransformation; D002143:Callitrichinae; D002233:Carbocysteine / Q000378:metabolism* / Q000652:urine; D003545:Cysteine / Q000031:analogs & derivatives*; D005243:Feces / Q000032:analysis; D005260:Female; D006168:Guinea Pigs; D000882:Haplorhini; D006801:Humans; D008297:Male; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013997:Time Factors
chemical_list: D002233:Carbocysteine; D003545:Cysteine