In vitro and in vivo models for evaluating drugs which influence arachidonic acid metabolism.
This paper describes several animal and human models, which are used for studying phospholipase, cyclo-oxygenase and thromboxane synthetase inhibitors.
D000818:Animals; D001095:Arachidonic Acids / Q000378:metabolism*; D002478:Cells, Cultured; D006801:Humans; D008954:Models, Biological; D009924:Organ Culture Techniques; D010740:Phospholipases / Q000378:metabolism; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism; D011453:Prostaglandins / Q000096:biosynthesis*; D013930:Thromboxane-A Synthase / Q000378:metabolism
D001095:Arachidonic Acids; D011453:Prostaglandins; D011451:Prostaglandin-Endoperoxide Synthases; D010740:Phospholipases; D013930:Thromboxane-A Synthase