title: [Analysis of the biological effect of city smog extract IV. Growth inhibition of kidney cell cultures (cercopithecus aethiops) under the influence of a city smog extract and its polyaromatic fractions (author's transl)].
abstract: The cell growth of exponentially growing kidney cell cultures of Cercopithecus aethiops was determined by estimation of protein content. The effect of city smog extracts and its polyaromatic fractions on cell growth was examined. Based on the benzo(a)pyren-content the crude extract of city smog exerted the strongest inhibition of cell growth, followed by non purified and purified fraction of polyaromates. The inhibition of cell growth was dose dependent. Results indicate, that for cell growth inhibition are of importance concentrations of toxic substances and exposition time.
mesh_terms: D000818:Animals; D001580:Benzopyrenes / Q000009:adverse effects; D002521:Cercopithecus; D046508:Culture Techniques; D004305:Dose-Response Relationship, Drug; D000882:Haplorhini; D007668:Kidney / Q000187:drug effects / Q000254:growth & development*; D012905:Smog; D013997:Time Factors
chemical_list: D001580:Benzopyrenes; D012905:Smog
vernacular_title: Untersuchung der biologischen Wirkung von atmosphärischen Feinstaubextrakten IV. Wachstumshemmung von Nierenzellkulturen (Cercopithecus aethiops) unter Einwirkung eines atmosphärischen Feinstaubextraktes und seiner Polyaromatenfraktionen.