[Rheumatism caused by lipid thesaurismosis. Articular involvement in hyperlipoproteinemia type II : presence of microcrystals in the mitochondria of synoviocytes].
For 13 years polyarthritis with specific synovial involvement was observed in a case of type II hyperlipoproteinemia. Microcrystals similar to those described in Gaucher's and Fabry's disease were seen in synovial cytoplasm and mitochondria. These data suggest a microcrystalline pathogenesis for type II hyperlipoproteinemia arthritis as in gout and chondrocalcinosis.
D000328:Adult; D001168:Arthritis / Q000209:etiology* / Q000473:pathology; D003460:Crystallization; D003593:Cytoplasm / Q000648:ultrastructure; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D006949:Hyperlipidemias / Q000150:complications* / Q000235:genetics* / Q000473:pathology; D008928:Mitochondria / Q000648:ultrastructure; D012216:Rheumatic Diseases / Q000209:etiology* / Q000473:pathology; D013583:Synovial Membrane / Q000648:ultrastructure*; D014973:Xanthomatosis / Q000150:complications / Q000473:pathology
Le rhumatisme des thésaurismoses à lipides. Atteinte articulaire au cours de l'hyperdyslipidémie de type II : présence de microcristaux dans les mitochondries des synoviocytes.