title: Protease inhibitors in porcine serum and their immunological relationships to human protease inhibitors.
abstract: A close molecular relationship exists between the protease inhibitors of porcine serum and those of human serum as shown by studying their immunological cross-reactivities with gel diffusion and immunoelectrophoretic methods. On studying seven different antisera to human protease inhibitors, five were found to cross-react with porcine serum, and on this bisis it was possible to identify alpha 2 -macroglobulin f, alpha 2 -macroglobulin s, alpha 1 -protease inhibitor, inter-alpha-trypsin inhibitor, antithrombin and alpha 2 -antiplasmin in porcine serum. Antisera to four of these porcine serum inhibitors (alpha 2 -macroglobulin f, alpha 2 -macroglobulin s, alpha 1 -protease inhibitor and inter-alpha-trypsin inhibitor) were produced and were shown to react immunologically with their human serum protease inhibitor counterparts.
mesh_terms: D000818:Animals; D003429:Cross Reactions; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D011480:Protease Inhibitors / Q000097:blood*; D013045:Species Specificity; D013552:Swine; D000511:alpha-Macroglobulins / Q000032:analysis
chemical_list: D011480:Protease Inhibitors; D000511:alpha-Macroglobulins