[Effect of 2 inhibitors of glycoprotein synthesis, tunicamycin and 2-deoxyglucose, on development of the sea urchin (Paracentrotus lividus) egg].
Tunicamycin, an inhibitor of glycoprotein synthesis, inhibits the development of the sea Urchin egg. Gastrulation is very sensitive to the Tunicamycin. Fertilization is not inhibited. 2-deoxy-D-glucose inhibits gastrulation and induces the hyperdevelopment of ectodermic structures.
D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D003837:Deoxy Sugars / Q000494:pharmacology*; D003847:Deoxyglucose / Q000494:pharmacology*; D005260:Female; D005306:Fertilization / Q000187:drug effects; D005944:Glucosamine / Q000031:analogs & derivatives*; D010063:Ovum / Q000187:drug effects*; D012617:Sea Urchins; D014415:Tunicamycin / Q000494:pharmacology*
D003837:Deoxy Sugars; D014415:Tunicamycin; D003847:Deoxyglucose; D005944:Glucosamine
Effets de deux inhibiteurs de la synthèse des glycoprotéines, Tunicamycine et 2-désoxyglucose, sur le développement de l'oeuf de l'oursin Paracentrotus lividus.