Complexity of cell interactions: analysis using antigens under Ir gene control.
The properties of three I region associated immunoregulatory factors involved in cell interactions are described. These are antigen specific T helper factor, suppressor factor produced by metabolically active T cells and genetically restricted factor, which is produced by macrophages and is involved in T helper cell induction. The use of these factors to analyse cell interactions is discussed.
D000818:Animals; D000917:Antibody Formation; D005802:Genes, MHC Class II; D007111:Immunity, Cellular; D007165:Immunosuppression Therapy; D008211:Lymphocyte Cooperation; D008214:Lymphocytes / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D051379:Mice; D010455:Peptides / Q000276:immunology
D010455:Peptides