title: [Modification of human adenovirus type 7 after culture in guinea pig brain cells in vitro].
abstract: Multiplication of human adenovirus 7 (Ad7) is restricted in subcultures of adult Guinea Pig brain cells. It was however possible to recover enough infectious virus to purify it, and to study its properties. Several properties are similar to that of Ad 7 produced in HeLa cells but differences in sensitivity to cesium chloride and in its polypeptide composition were found.
mesh_terms: D000260:Adenoviruses, Human / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000382:microbiology*; D002478:Cells, Cultured; D002499:Centrifugation, Density Gradient; D006168:Guinea Pigs; D006367:HeLa Cells / Q000378:metabolism; D006801:Humans; D008970:Molecular Weight; D010455:Peptides / Q000032:analysis; D014764:Viral Proteins / Q000096:biosynthesis; D014779:Virus Replication
chemical_list: D010455:Peptides; D014764:Viral Proteins
vernacular_title: Modifications de l'adénovirus humain type 7 après culture sur cellules provenant de cerveau de Cobaye.