[Stimulating determinants of the secondary mixed lymphocyte reaction (MLR-II)].
An anti-Ia immune serum (A . TL anti-A . TH) directed to the antigens of the stimulating cell, blocked the MLR-II. A significant correlation was observed between the anti-Ia reactivity of the immune serum, studied against a panel of eleven original H-2 haplotypes and the reactivity against the same panel of the in vitro primed responding cells (A . TL anti-A . TH). These results confirm the hypothesis that Ia antigens are the structures stimulating the MLR-II.
D000818:Animals; D000917:Antibody Formation; D000936:Antigen-Antibody Complex; D002478:Cells, Cultured; D000939:Epitopes; D007106:Immune Sera; D051379:Mice; D013601:T-Lymphocytes / Q000276:immunology*
D000936:Antigen-Antibody Complex; D000939:Epitopes; D007106:Immune Sera
Etude des déterminants responsables de la stimulation lors de la réaction lymphocytaire mixte secondaire (MLR-II).