[Stenosis and intestinal ulcer due to chronic ingestion of a combination of a thiazidic diuretic with potassium].
Reports from recent years shown evidence of the existence of a type of primary ulceration of the small bowel associated with stenosis, relatively frequent and possibly iatrogenic. The primary characteristics of the studied cases were that it was present in patients over 50 years old, a good number of them had cardiorenal diseases or were hypertensives, and ingestion of a thiazide diuretic supplemented with potassium. Clinical and experimental investigations suggest that potassium, with or without a diuretic, could cause ulceration and stenosis of the small bowel. Presented in this report the case of a 62-year-old patient with cardiovascular disease and chronic ingestion of a thiazide diuretic with potassium chloride (Diclotride-K (R) who developed an intestinal obstruction that merited surgical intervention which showed a circumscribed stenosis of jejunum accompanied by ulceration.
D001581:Benzothiadiazines; D004232:Diuretics; D004359:Drug Therapy, Combination / Q000009:adverse effects; D006801:Humans; D007415:Intestinal Obstruction / Q000139:chemically induced* / Q000473:pathology; D007583:Jejunum / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy; D011189:Potassium Chloride / Q000009:adverse effects*; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects*; D014456:Ulcer / Q000139:chemically induced / Q000473:pathology
D001581:Benzothiadiazines; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors; D011189:Potassium Chloride
Estenósis y ulceración intestinal asociada a ingestion crónica de una combinación de diurético tiazídico con potasio.