title: [Hypothyreotic connatal struma after amniofetography (author's transl)].
abstract: It is reported on a newborn suffering from a pronounced hypothyreosis and a big goitre caused by an amniofetography during the 22. week of pregnancy using a hydrous and a oily iodiferous drug. The big goitre impeded the respiration, so that intubation was indicated. After treatment with thyroid hormones for 8 months the goitre decreased. The thyroid hormone-levels and function tests were in normal range after interruption of the thyroid drugs. Etiology and pathogenesis of this disease are discussed. It is warned of using drugs containing high iodine doses for amnio- or fetography.
mesh_terms: D003287:Contrast Media / Q000009:adverse effects*; D004417:Dyspnea / Q000628:therapy; D005260:Female; D005332:Fetoscopy; D006042:Goiter / Q000139:chemically induced; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced*; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007442:Intubation, Intratracheal; D007457:Iodine Radioisotopes / Q000009:adverse effects; D011247:Pregnancy; D013960:Thyroid Function Tests
chemical_list: D003287:Contrast Media; D007457:Iodine Radioisotopes
vernacular_title: Hypothyreote konnatale Struma nach Amniofetographie.