title: [Evidence and estimation of immunoglobulins in human nasal mucosa and nasal fluid--a study towards age dependence (author's transl)].
abstract: The localization of IgA, IgG and IgM in healthy human nasal mucosa in relation to age--a fluorescence-microscopic study as well as simultaneous quantitative estimation of these immunoglobulins in nasal fluid. These investigations confirm the dominant role of IgA. The IgA concentrations decreases with age. IgG concentration is nearly independent of age. IgM scarlely existing in normal human mucosa and nasal fluid.
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging; D002648:Child; D002675:Child, Preschool; D005455:Fluorescent Antibody Technique; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D007223:Infant; D008875:Middle Aged; D009093:Mucus / Q000276:immunology*; D009297:Nasal Mucosa / Q000276:immunology* / Q000378:metabolism
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Immunglobulinnachweis in der Nasenschleimhaut und im Nasensekret des Menschen Eine Studie zur Altersabhängigkeit.