[A control trial of home I.P.P.B. therapy in patients with chronic obstructive respiratory insufficiency. Protocol and state of the study (author's transl)].
Because a previous retrospective study did not allow any conclusion as to the efficacy of home IPPB therapy in patients with chronic airflow obstruction, a control trial has been started. The protocol includes definition of patients, modalities of treatment, criteria for evaluation. Among criteria for a patient to enter the trial is a chronic hypercapnia (with PaCO2 greater than or equal to 48 mmHg) observed over a preliminary period of 4 months. At the end of this period patients are allocated at random into two groups with and without IPPB at home (at least 1 to 2 hours daily through a mouthpiece); medical prescriptions are same in the 2 groups so as surveillance which is planned for 2 years. Evaluation should be based upon 5 predetermined criteria. This trial is in progress.
D000203:Activities of Daily Living; D002245:Carbon Dioxide / Q000097:blood; D002986:Clinical Trials as Topic / Q000379:methods*; D006701:Home Nursing; D006801:Humans; D006935:Hypercapnia / Q000628:therapy; D007384:Intermittent Positive-Pressure Breathing / Q000592:standards*; D010100:Oxygen / Q000097:blood; D011175:Positive-Pressure Respiration / Q000592:standards*; D011379:Prognosis; D012131:Respiratory Insufficiency / Q000628:therapy*
D002245:Carbon Dioxide; D010100:Oxygen
Présentation d'un essai thérapeutique en cours concernant la ventilation assistée à domicile chez les insuffisants respiratoires chroniques de type obstructif.