title: Rickets as a complication of intravenous hyperalimentation in infants.
abstract: Fifteen newborn infants developed roentgenographic evidence of rickets while on long-term intravenous hyperalimentation. In each instance, the initial diagnosis of rickets was suggested on the chest roentgenogram, where characteristic cupped and frayed upper humeral metaphyses were noted; subsequent knee and wrist roentgenograms substantiated these findings. Factors which may have predisposed to the development of rickets include inadequate doses of vitamin D, prematurity and a rapid change in body weight during hyperalimentation therapy.
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D010288:Parenteral Nutrition / Q000009:adverse effects*; D010289:Parenteral Nutrition, Total / Q000009:adverse effects*; D011859:Radiography; D012279:Rickets / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D014807:Vitamin D / Q000627:therapeutic use
chemical_list: D014807:Vitamin D