title: Persistence and reactivation of Rickettsia tsutsugamushi infections in laboratory mice.
abstract: The persistence of R. tsutsugamushi in tissues of experimentally infected mice for 565 days was demonstrated. Reactivation of apparently dormant infections was accomplished by inoculating the mice with a heterologous strain of the organism or treatment with cyclophosphamide.
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D003520:Cyclophosphamide / Q000494:pharmacology; D005260:Female; D007165:Immunosuppression Therapy; D051379:Mice; D012285:Orientia tsutsugamushi / Q000276:immunology; D010962:Plasmodium berghei / Q000276:immunology; D012008:Recurrence; D012612:Scrub Typhus / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D003520:Cyclophosphamide