title: Cutaneous melanoma in a patient with neurofibromatosis.
abstract: Although neurofibromatosis and cutaneous melanoma are both diseases of neuroectodermal origin, reports of their association are rare. The case history of a patient with histologically documented neurofibromatosis and a nodular melanoma unrelated to a cafe-au-lait spot or congenital nevus is reported, and the literature reviewed. The appearance of only one patient with neurofibromatosis in a series of 900 patients with melanoma suggests that these diseases are probably not associated with greater frequency than that predicted by chance alone.
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D008545:Melanoma / Q000150:complications* / Q000473:pathology; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology