title: [Nuclear proteins and DNA in the myocardial myocytes in compensatory cardiac hypertrophy].
abstract: Using cytophotometry, the amount of DNA, total nuclear proteins and of histones were studied in the myocardial cells during days 21--36 of experimental compensatory hypertrophy of the heart (in rats). The enlargement of myocardial nuclei during the cardial hyperfunction was accompanied by accumulation of total nuclear protein, in particular, the histone fraction, without distinct changes in DNA. Analysis of correlations between nuclear proteins and DNA in the myocardial cells allows to reveal a delayed accumulation of histones in the big and gigantic nuclei, with a superfluous increase in non-histone nuclear proteins. In middle-sized nuclei, non-histone proteins have little changes against intensive accumulation of histones.
mesh_terms: D000818:Animals; D001018:Aortic Diseases / Q000150:complications; D006332:Cardiomegaly / Q000209:etiology / Q000473:pathology*; D002467:Cell Nucleus / Q000032:analysis / Q000378:metabolism*; D003251:Constriction, Pathologic / Q000150:complications; D004247:DNA / Q000032:analysis / Q000378:metabolism*; D006657:Histones / Q000378:metabolism; D009206:Myocardium / Q000473:pathology*; D009698:Nucleoproteins / Q000032:analysis / Q000378:metabolism*; D010783:Photometry / Q000379:methods; D051381:Rats
chemical_list: D006657:Histones; D009698:Nucleoproteins; D004247:DNA
vernacular_title: Iadernye belki i DNK v miotsitakh miokarda pri kompensatornoĭ gipertroffi serdtsa.