[Morphological changes in the digestive organs during prolonged space flight on the Kosmos-782 biosatellite].
A reduction in the content of neutral mucopolysaccharides in mucous cells of the neck, a slight decrease in the activity of succinate dehydrogenase and NAD-diaphorase in parietal cells, a decrease in the DNA synthesis rate, and an increase in the area of mitochondria and cristae were detected in the gastric mucosa of rats which were in a long-term space flight. In the small intestine, an increase in the activity of glucose-6-phosphate dehydrogenase and leucine aminopeptidase were found. Morphological changes in the liver consisted in infiltrative adiposity. A similar morphological picture was demonstrated in a synchronous experiment on the earth. These changes, however, were nonspecific and reversible (25 days after rehabilitation the picture did not differ from the animal house control).
D000222:Adaptation, Physiological; D000818:Animals; D004247:DNA / Q000096:biosynthesis; D004064:Digestive System / Q000503:physiopathology*; D004789:Enzyme Activation; D005234:Fatty Liver / Q000503:physiopathology; D005753:Gastric Mucosa / Q000503:physiopathology; D006025:Glycosaminoglycans / Q000378:metabolism; D007413:Intestinal Mucosa / Q000503:physiopathology; D008099:Liver / Q000503:physiopathology; D010179:Pancreas / Q000503:physiopathology; D051381:Rats; D013026:Space Flight; D013997:Time Factors; D014586:USSR
D006025:Glycosaminoglycans; D004247:DNA
Morfologicheskie izmeneniia organov pishchevareniia pri dlitel'nom kosmicheskom polete na biosputnike "Kosmos-782".