Alteration of erythrocyte (see article) -ATPase by replacement of cholesterol by desmosterol in the membrane.
Cholesterol of red blood cells (RBC) is readily exchanged by desmosterol and vice versa. The resulting alteration in the sterol composition influences the specific (Na+ plus K+)-ATPase activity. It is suggested that this effect is due to an altered membrane fluidity.
D000251:Adenosine Triphosphatases / Q000097:blood*; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D002784:Cholesterol / Q000097:blood*; D003897:Desmosterol / Q000097:blood*; D004912:Erythrocytes / Q000201:enzymology* / Q000648:ultrastructure; D008297:Male; D011188:Potassium; D051381:Rats; D012964:Sodium; D013268:Stimulation, Chemical
D003897:Desmosterol; D002784:Cholesterol; D012964:Sodium; D000251:Adenosine Triphosphatases; D011188:Potassium