Changes in some marker enzyme activities of liver plasma membranes during regeneration after partial hepatectomy in rats.
Liver plasma membranes were isolated from regenerating rat livers between 20 h and 10 days after partial hepatectomy in order to study the effect of partial hepatectomy on some membrane enzyme activities. Mg2+-ATPase (EC 3.6.1.4) activity, but not (Na+ + K+)-ATPase activity, decreased slightly at 2 days, whereas leucyl beta-naphthylamidase (EC3.4.1.1) and 5'-nucleotidase (EC3.1.3.5) activities increased considerably at 1-2 and 3-5 days, respectively. These changes were not parallel to a sharp increase in mitotic activity of liver cells which occurred at 36 h.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D002462:Cell Membrane / Q000201:enzymology*; D004247:DNA / Q000096:biosynthesis; D005260:Female; D006498:Hepatectomy; D007931:Leucyl Aminopeptidase / Q000378:metabolism; D008099:Liver / Q000201:enzymology* / Q000378:metabolism; D008115:Liver Regeneration; D008274:Magnesium / Q000494:pharmacology; D008938:Mitosis; D009708:Nucleotidases / Q000378:metabolism; D009929:Organ Size; D011188:Potassium / Q000494:pharmacology; D014176:Protein Biosynthesis; D051381:Rats; D012964:Sodium / Q000494:pharmacology; D013997:Time Factors
D004247:DNA; D012964:Sodium; D009708:Nucleotidases; D007931:Leucyl Aminopeptidase; D000251:Adenosine Triphosphatases; D008274:Magnesium; D011188:Potassium