Effect of glucagon on glucose and fatty acid metabolism in goats.
Adult goats of a white breed were injected i.v. with glucagon in doses of 6.25--25 mug/kg. The blood sugar curve rose relatively slowly after the injection after the injection and the maximum increase, which attained 360--400% of the resting value was usually recorded 20-30 min after glucagon administration. The non-esterified fatty acid (NEFA) level rose immediately after injecting glucose. Within 10 min it returned to the initial value and then fell abruptly. No concentration correlation was found between the glucagon dose and the size of the metabolic response.
D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D004734:Energy Metabolism / Q000187:drug effects; D005230:Fatty Acids, Nonesterified / Q000378:metabolism*; D005934:Glucagon / Q000008:administration & dosage / Q000494:pharmacology*; D006041:Goats / Q000378:metabolism*; D007275:Injections, Intravenous
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D005934:Glucagon