[Comparison of plasma testosterone (T), androstenedione (A) and dhea variations after métopirone in 10 normal and 12 hirsute women (author's transl)].
Plasma testosterone; androstenedione and DHA were measured by radio-immunoassay before (J1) under (J2) and 24-hour after (J3) oral metyrapone (4,5 g) in 10 normal and 12 hirsute women. Although individual values were dispersed, hirsute women, as a group, had significantly higher values at each time for each steroid. Hirsute women with normal basal T had normal T and A values for J1, J2, J3; while these with elevated basal T had elevated T and A value for all samples. Plasma DHEA was elevated in the two groups, before, under and after métopirone.
D000284:Administration, Oral; D000735:Androstenedione / Q000097:blood*; D003687:Dehydroepiandrosterone / Q000097:blood*; D005260:Female; D006628:Hirsutism / Q000097:blood*; D006801:Humans; D008797:Metyrapone / Q000008:administration & dosage*; D013739:Testosterone / Q000097:blood*
D013739:Testosterone; D000735:Androstenedione; D003687:Dehydroepiandrosterone; D008797:Metyrapone
Comparaison des variations de la testostérone (T) de l'androsténedione (A) et de la déhydroépiandrostérone (DHA) plasmatiques sous l'effet de la métopirone (S.U.) chez 10 femmes normales et 12 hirsutes.