[Evidence, in the epididymis, of a strong lowering factor for blood FSH in rats].
The supernatant of centrifuged epididymis homogenates was injected in the peritoneum of castrated Wistar rats for three days. It involves a strong decrease of FSH in the blood plasma, without a significant change of LH and LTH, measured by radioimmuno-assay. Now ligating the vasa efferentes --- but not the epididymis corpus --- involves an increase of the plasma FSH, as we showed in a previous paper. Then we conclude that testicular inhibin gets into the blood stream through the head of the epididymis.
D000818:Animals; D002369:Castration; D004822:Epididymis / Q000502:physiology*; D005640:Follicle Stimulating Hormone / Q000097:blood*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D011863:Radioimmunoassay; D051381:Rats; D013737:Testis / Q000502:physiology
D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Présence dans l'épididyme d'un facteur abaissant fortement le taux sanguin de FSH chez le rat.