Contact dermatitis from pyrrolnitrin (an antimycotic agent).
Two cases are described of acute contact dermatitis from an antifungal cream, containing pyrrolnitrin, employed for the treatment of tinea cruris. Positive reactions to pyrrolnitrin and to a chemically related substance, 1-chlor-2,4dinitrobenzene, were put into evidence.
D000208:Acute Disease; D000328:Adult; D000935:Antifungal Agents / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology*; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments; D010328:Patch Tests; D011764:Pyrrolnitrin / Q000009:adverse effects*
D000935:Antifungal Agents; D009824:Ointments; D011764:Pyrrolnitrin