[Histotopochemical investigations on elastic membranes of blood vessels with special regard to diabetes mellitus. I. Proteins (author's transl)].
Histochemical investigations on elastic membranes of vessels under normally and diabetic conditions have been accomplished. These studies were made on man (diabetic and non-diabetic subjects) and on rats with streptozotocin-diabetes. The results are comparable among one another. The amino acids histidine, tyrosine and tryptophan were not demonstrable. The detection of primary NH2-groups (ninhydrin-Schiff-method and o-diacetylbenzen-reaction) was positive however. The results of the reactions in healthy men and animals were more distinct than in diabetic human subjects and animals. In healthy children the intensities of the histochemically reactions were higher than in adults.
D000328:Adult; D000367:Age Factors; D000596:Amino Acids / Q000032:analysis*; D000818:Animals; D001158:Arteries / Q000032:analysis*; D002648:Child; D003920:Diabetes Mellitus / Q000139:chemically induced / Q000378:metabolism*; D003925:Diabetic Angiopathies / Q000378:metabolism; D004547:Elastic Tissue / Q000032:analysis*; D004549:Elastin / Q000032:analysis; D006639:Histidine / Q000032:analysis; D006651:Histocytochemistry; D006801:Humans; D051381:Rats; D013311:Streptozocin; D014364:Tryptophan / Q000032:analysis; D014443:Tyrosine / Q000032:analysis
D000596:Amino Acids; D014443:Tyrosine; D006639:Histidine; D013311:Streptozocin; D014364:Tryptophan; D004549:Elastin
Histotopochemische Untersuchungen an elastischen Membranen der Blutgefässe unter besonderer Berücksichtigung des Diabetes mellitus. I. Proteine