title: Spectinomycin-resistant Neisseria gonorrhoeae.
abstract: Neisseria gonorrhoeae resistant to high levels of spectinomycin (more than 2,048 microng/ml), were isolated from specimens obtained from a patient with urethritis. The bacterial resistance to spectinomycin is probably due to ribosomal changes that are a result of a chromosomal mutation. If spectinomycin fails to cure gonorrhea, spectinomycin resistance should be considered.
mesh_terms: D000328:Adult; D004352:Drug Resistance, Microbial; D005845:Georgia; D006069:Gonorrhea / Q000188:drug therapy; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D009344:Neisseria gonorrhoeae / Q000187:drug effects*; D000198:Spectinomycin / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000198:Spectinomycin