title: [The phenomenon of water entrapment in the formation and course of edema. A physiopathological mechanism useful for therapeutic purposes].
abstract: Results with a diffusor enzyme (thiomucasi) in the medical management of oedema in 29 subjects are presented. This substance was used on the assumption that interstitial mucopolysaccharides trap water by means of a polymerisation-depolymerisation process, so that its release necessitates rupture of chemicophysical bonds. The results point to the effectiveness of the drug and the soundness of this interpretation.
mesh_terms: D000368:Aged; D001769:Blood; D002199:Capillary Permeability; D003238:Connective Tissue / Q000378:metabolism; D004487:Edema / Q000209:etiology* / Q000378:metabolism / Q000628:therapy; D005260:Female; D006025:Glycosaminoglycans / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D009997:Osmotic Pressure; D011133:Polysaccharide-Lyases / Q000627:therapeutic use*; D014867:Water / Q000378:metabolism*
chemical_list: D006025:Glycosaminoglycans; D014867:Water; D011133:Polysaccharide-Lyases
vernacular_title: Il fenomeno dell'intrappolamento dell'acqua nella formazione ed evoluzione dell'edema. Un meccanismo fisiopatologico utilizzabile a fini terapeutici