title: Surgical treatment for anomalous origin of left coronary artery from pulmonary artery.
abstract: Anomalous origin of the left coronary artery from the pulmonary artery carries a poor prognosis; most patients die early in life from myocardial infarction and congestive heart failure. During a 12-year period at the Texas Heart Institute, 13 patients with this congenital malformation ranging in age from 1 to 24 years underwent operation. The anomalous coronary artery was sutured or ligated, or both, close to the pulmonary artery in 3 patients, 2 before 1965. Aortocoronary bypass was performed in the remaining 10 patients, using an autogenous saphenous vein graft in 9 and a Dacron tube in 1. More recently a distal end-to-side anastomosis has been employed and is not the preferred method. If necessary, a pump oxygenator may be used to complete the procedure. The only death was that of the first patient in the series who underwent ligation of the left coronary artery and mitral annuloplasty for severe mitral insufficiency; Of the 12 patients available for long-term follow-up study, all but 1 were asymptomatic. Follow-up angiographic studies showed the graft to be patent in 7 patients; the longest period of graft patency was 8 years. Definitive operative therapy is preferable to simple ligation because it eliminates the left-to-right shunt from the right coronary artery to the pulmonary artery and establishes a double coronary artery system.
mesh_terms: D000293:Adolescent; D000328:Adult; D001807:Blood Vessel Prosthesis; D002648:Child; D002675:Child, Preschool; D001026:Coronary Artery Bypass; D003330:Coronary Vessel Anomalies / Q000601:surgery*; D005112:Extracorporeal Circulation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008026:Ligation; D008297:Male; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000601:surgery; D011093:Polyethylene Terephthalates; D011651:Pulmonary Artery / Q000002:abnormalities*; D013536:Suture Techniques; D014182:Transplantation, Autologous; D014680:Veins / Q000637:transplantation
chemical_list: D011093:Polyethylene Terephthalates