title: [Estimation of individual renal function by Tc-DMSA-uptake (author's transl)].
abstract: Hg-Cl2-accumulation and early hippuran uptake are widely used for the estimation of individual renal function, a clinically important procedure in nephrological-urological nuclear medicine. After clinical experience in more than 2500 patients we investigated the assessment of individual renal function by the uptake of Tc-DMSA, a new radiopharmaceutical for renal scintigraphy. Tc-DMSA-uptake was measured after application of 0.8-1.6 mCi Tc-99m-DMSA by a scintillation camera connected to a computer system and by a rectilinear scanner with data storage, additionally hippuran kinetics were registered with a scintillation camera, the total body clearance was performed due to the method of Oberhausen with a modified whole body counter. A good agreement and high correlation between Tc-DMSA-uptake with background corection and the unilateral renal clearance could be established. This easily available and clinically valuable method also can be adjusted to institutions with a rather simple equipment.
mesh_terms: D005069:Evaluation Studies as Topic; D006801:Humans; D007677:Kidney Function Tests / Q000379:methods*; D011866:Radioisotope Renography; D011877:Radionuclide Imaging; D013386:Succinates; D013667:Technetium
chemical_list: D013386:Succinates; D013667:Technetium
vernacular_title: Abschätzung der seitengetrennten Nierenfunktion mittels der 99mTc-DMSA-Aufnahme.