Cutaneous hydroxystereoid dehydrogenases and rat-hair cycle.
The histochemical activity pattern of a number of hydroxysteroid dehydrogenases was studied during a provoked hair cycle in the rat skin. The intensity of reaction was high with dehydroepiandrosterone, estradiol, androsterone and pregnenolone, and none with 11-beta-hydroxyprogesterone, testosterone, dihydrotestosterone, 17-alpha-hydroxypregnenolone and 17-alpha-hydroxyprogesterone. Reactivity also varied with the hair cycle. The reactive sit-s were the acini of sebaceous glands and the hair sheaths.
D006907:17-alpha-Hydroxypregnenolone; D000738:Androsterone; D000818:Animals; D003593:Cytoplasm / Q000201:enzymology; D003594:Cytoplasmic Granules / Q000201:enzymology; D003687:Dehydroepiandrosterone; D013196:Dihydrotestosterone; D004958:Estradiol; D006197:Hair / Q000201:enzymology / Q000254:growth & development*; D006651:Histocytochemistry; D006908:Hydroxyprogesterones / Q000031:analogs & derivatives; D006913:Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D008297:Male; D011284:Pregnenolone; D051381:Rats; D012627:Sebaceous Glands / Q000201:enzymology; D012867:Skin / Q000201:enzymology*; D013739:Testosterone
D006908:Hydroxyprogesterones; D013196:Dihydrotestosterone; D006907:17-alpha-Hydroxypregnenolone; D013739:Testosterone; D003687:Dehydroepiandrosterone; D004958:Estradiol; D011284:Pregnenolone; D000738:Androsterone; D006913:Hydroxysteroid Dehydrogenases