Oxidative biotransformation of di-n-butylnitrosamine. Formation in vitro of aldehydes in the presence of rat liver microsomes.
After in vitro incubation of di-n-butylnitrosamine with rat liver microsomes in the presence of the necessary cofactors butyraldehyde has been identified as a reaction product together with smaller amounts of propionaldehyde and acetaldehyde.
D000818:Animals; D006900:Hydroxylation; D066298:In Vitro Techniques; D008862:Microsomes, Liver / Q000378:metabolism*; D009602:Nitrosamines / Q000378:metabolism*; D010084:Oxidation-Reduction; D051381:Rats
D009602:Nitrosamines