[Effect of adrenaline on the ATPase activity of suslik brain synaptosomes].
Action of adrenaline on ATPase activity of ground squirrel synaptosomes in vitro at 37 degrees and 17 degrees C was studied. It has been shown in experiments in vitro at 37 degrees C that adrenaline in a concentration of 5.10(-4) M influenced Mg and Na, K-ATPase of the synaptosomes in ground squirrel brain. The inhibition (42-72%) of Na, K-ATPase in the synaptosomes of the brain was seen during hibernation and in summer. The inhibition of Mg-ATPase (50%) was observed only in summer. The effect of adrenaline on the activity of Na, K-ATPase of synaptosome was seen in vitro as well as at 17 degrees (a 50% inhibition). It was shown that adrenaline in vitro at a concentration of 5.10(-4) M inhibited ATPases more than noradrenaline.
D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors*; D000818:Animals; D001921:Brain / Q000201:enzymology* / Q000648:ultrastructure; D004837:Epinephrine / Q000494:pharmacology*; D066298:In Vitro Techniques; D008274:Magnesium / Q000378:metabolism; D011188:Potassium; D012589:Sciuridae; D012621:Seasons; D012964:Sodium; D013574:Synaptosomes / Q000201:enzymology*
D012964:Sodium; D000251:Adenosine Triphosphatases; D008274:Magnesium; D011188:Potassium; D004837:Epinephrine
Deĭstvie adrenalina na ATFaznuiu aktivnost' sinaptosom mozga suslikov.