title: [The effect of tri-iodinated contrast media on clotting. An investigation of thrombocyte aggregation (author's transl)].
abstract: In vitro investigations showed that renographic and cholecystographic contrast media reduced thrombocyte aggregation proportionate to contrast concentration. In vivo this disturbance of thrombocyte function could not be demonstrated. Other factors investigated, such as clotting time and thrombocyte counts, remained unaffected in vivo and in vitro. Age and sex and the presence of various types of pathology were also found to have no affect. These findings and their significance are discussed.
mesh_terms: D000367:Age Factors; D001777:Blood Coagulation / Q000187:drug effects; D001780:Blood Coagulation Tests; D003287:Contrast Media / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D007455:Iodine; D010974:Platelet Aggregation / Q000187:drug effects*; D012737:Sex Factors
chemical_list: D003287:Contrast Media; D007455:Iodine
vernacular_title: Einfluss trijodierter Röntgenkontrastmittel auf die Blutgerinnung. Untersuchung der Thrombozytenaggregation.