title: Cytogenetic darkroom magic: now you see them, now you don't.
abstract: Customary procedures used to determine chromosomal inheritance do not disclose many of the chromosomal polymorphisms known to be present, resulting in uninformative families. The sequential printing of individual chromosomes presented here is a technique that has increased the number of informative families in our studies. This technique has revealed previously unseen heritable chromosome differences and allowed the designation of parental origin.
mesh_terms: D002904:Chromosomes, Human, 21-22 and Y; D004314:Down Syndrome / Q000235:genetics*; D006801:Humans; D007621:Karyotyping / Q000379:methods*; D011797:Quinacrine Mustard; D014314:Trisomy
chemical_list: D011797:Quinacrine Mustard