Pharmacologic effects of apomorphine in rats with altered level of brain serotonin.
The influence of inhibitors and precursors of serotonin synthesis on motor stimulation, hypothermia and apomorphine-induced stereotypy was studied. The results are discussed with reference to the previously expressed suggestion of a modulating role of serotonin on the mechanism of apomorphine-induced motility and in apomorphine-induced hypothermia.
D006916:5-Hydroxytryptophan / Q000494:pharmacology; D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D001545:Benserazide / Q000494:pharmacology; D001831:Body Temperature / Q000187:drug effects; D001923:Brain Chemistry; D005260:Female; D010134:Fenclonine / Q000494:pharmacology; D006801:Humans; D009043:Motor Activity / Q000187:drug effects; D010293:Pargyline / Q000494:pharmacology; D051381:Rats; D012701:Serotonin / Q000032:analysis*; D013050:Spectrometry, Fluorescence; D013239:Stereotyped Behavior / Q000187:drug effects; D010133:p-Chloroamphetamine / Q000494:pharmacology
D012701:Serotonin; D010133:p-Chloroamphetamine; D001545:Benserazide; D010293:Pargyline; D006916:5-Hydroxytryptophan; D001058:Apomorphine; D010134:Fenclonine