An abnormality in sebaceous function in phenylketonuria.
The sebum excretion rate has been found to be increased in female patients with phenylketonuria. This may be related to a depletion of midbrain dopamine and release of the sebotrophic hormone.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001923:Brain Chemistry; D012628:Dermatitis, Seborrheic / Q000150:complications / Q000188:drug therapy; D004298:Dopamine / Q000032:analysis / Q000378:metabolism; D005260:Female; D006801:Humans; D007980:Levodopa / Q000494:pharmacology / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010661:Phenylketonurias / Q000150:complications / Q000503:physiopathology*; D012627:Sebaceous Glands / Q000187:drug effects; D012629:Sebum / Q000378:metabolism*; D012636:Secretory Rate; D012737:Sex Factors
D007980:Levodopa; D004298:Dopamine