title: [Change in the activity of epidermal chalones during skin reaction to the effect of a carcinogen and epilation].
abstract: The biological activity of an epidermal G2-chalone extracted from the rat back skin was found to decrease 1 to 2 days after the treatment with methylnitrosourea (a carcinogen), and one day after the epilation. Results of quantitative recording and morphological analysis of the skin serving as the source of chalones, pointed to different mechanisms which underlay this effect.
mesh_terms: D000818:Animals; D006131:Growth Inhibitors / Q000494:pharmacology / Q000502:physiology*; D006204:Hair Removal; D008770:Methylnitrosourea / Q000494:pharmacology*; D051379:Mice; D008938:Mitosis / Q000187:drug effects; D009607:Nitrosourea Compounds / Q000494:pharmacology*; D051381:Rats; D012038:Regeneration; D012867:Skin / Q000166:cytology* / Q000187:drug effects; D014020:Tissue Extracts / Q000494:pharmacology
chemical_list: D006131:Growth Inhibitors; D009607:Nitrosourea Compounds; D014020:Tissue Extracts; D008770:Methylnitrosourea
vernacular_title: Izmenenie aktivnosti epidermal'nykh keĭlonov v protsesse otvetnoĭ reaktsii kozhi na vozdeĭstvie kantserogenom i vyshchipyvanie.