title: Cohesion of horny cells during comedo formation. An electron microscope study.
abstract: Cohesion between horny cells was studied in experimentally induced comedones, from the rabbit's external ear canal. It occurred in two different ways: initially, by the persistence of desmosones and desmonosmal bodies (fusiform electron dense bodies), which loosely held the horny cells together; later, and to a lesser extent, by tight junctions, which tightly bound the horny cells together. A gradual decrease in the numbers of membrane coating granules was observed.
mesh_terms: D000152:Acne Vulgaris / Q000473:pathology*; D000818:Animals; D002448:Cell Adhesion; D003896:Desmosomes / Q000648:ultrastructure; D007365:Intercellular Junctions / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D011817:Rabbits; D012867:Skin / Q000648:ultrastructure*