Sarcoma associated with dacron prosthetic material: case report and review of the literature.
A case of a fibrosarcoma arising in association with a Dacron prosthetic graft is reported. This is the second report of such an association. Animal studies have shown that polymeric substances can induce similar sarcomas and that pore size between the polymeric strands is an important consideration in determining carcinogenicity. Grafts with pore size less than 0.4 mu in diameter should be avoided in man until they are absolutely proved incapable of tumorogenesis.
D000671:Amputation, Surgical; D001012:Aorta, Abdominal / Q000473:pathology; D001014:Aortic Aneurysm / Q000601:surgery; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates / Q000009:adverse effects*; D011859:Radiography; D012509:Sarcoma / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000601:surgery
D011093:Polyethylene Terephthalates