[Tissue-specific inhibition of cellular proliferation in Ehrlich ascites tumor].
The extract of cells of ascitic Ehrlich's tumour (chaloun) and its cell-free fluid produced a marked inhibitory action on the cell proliferation of this tumour four hours after the administration. The effect is tissue-specific, more pronounced in the extract and depends on the dose of the antigen. Eight hours after the extract or the cell-free fluid administration the mitotic activity in the tumour proved to increase in comparison with control; this indicated the presence of a short-lived chaloun action on the G2-phase of the mitotic cycle and synchronization of cell division.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000032:analysis / Q000628:therapy*; D005110:Extracellular Space / Q000032:analysis; D006131:Growth Inhibitors / Q000302:isolation & purification / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D008940:Mitotic Index
D006131:Growth Inhibitors
Tkanevospetsificheskaia ingibitsiia kletochnoĭ proliferatsii v astsitnoĭ opukholi Erlikha