title: [ATP and ATPase activity in the liver and brain cell fractions of gamma-irradiated chick embryos and newly hatched chicks].
abstract: Studied were the level of ADP and the adenosinetriphosphatase in nuclei, mitochondria, and microsomes taken from the brain and liver of singly gamma-irradiated at 1000 rd chick embryos and birds. As a result of the treatment of ADP content dropped, while the activity ADP rose. These changes were most strongly expressed in the nuclei, then in the mitochondria, and to a lesser extent-in the microsomes. Twelve-day chick embryos showed more markedly expressed radiosensitivity than newly hatched chicks. This embryonal state is characterized by intense growth, differentiation and metabolic processes in the liver, which substantiate not only the higher radiosensitivity of this age group but the more strongly expressed changes in the liver as compared with the brain.
mesh_terms: D000251:Adenosine Triphosphatases / Q000528:radiation effects*; D000255:Adenosine Triphosphate / Q000528:radiation effects*; D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism*; D001921:Brain / Q000166:cytology / Q000528:radiation effects*; D002467:Cell Nucleus / Q000528:radiation effects; D002642:Chick Embryo; D004789:Enzyme Activation / Q000528:radiation effects; D005720:Gamma Rays; D008099:Liver / Q000166:cytology / Q000528:radiation effects*; D008861:Microsomes / Q000528:radiation effects; D008862:Microsomes, Liver / Q000528:radiation effects; D008928:Mitochondria / Q000528:radiation effects; D008930:Mitochondria, Liver / Q000528:radiation effects; D011836:Radiation Tolerance; D013997:Time Factors
chemical_list: D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases
vernacular_title: ATF i ATF-azna aktivnost v kletuchni fraktsii ot cheren drob i mozuk na oblucheni s gamma-luchi kokoshi embrioni i novoizliupeni pileta.