Acne vulgaris: treatment with topical benzoyl peroxide acetone gel.
The topical effect on acne of a benzoyl peroxide acetone gel was studied over an eight week period and simultaneously compared with the effect of a benzoyl peroxide lotion and a vitamin A acid cream. The three formulations produced a significant reduction in the number of comedones. The two benzoyl peroxide formulations substantially reduced the number of papules, but this effect was not observed to a significant degree with the vitamin A acid. Burning sensation following application, a common problem with the benzoyl peroxide alcohol gels, was not reported by patients using the benzoyl peroxide acetone gel.
D000152:Acne Vulgaris / Q000188:drug therapy*; D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D001585:Benzoyl Peroxide / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D005782:Gels; D006801:Humans; D008297:Male; D010545:Peroxides / Q000008:administration & dosage*; D014212:Tretinoin / Q000008:administration & dosage / Q000627:therapeutic use
D005782:Gels; D010545:Peroxides; D014212:Tretinoin; D001585:Benzoyl Peroxide