[Electrical activity of cultured cells of the guinea pig heart. Comparison with the rat].
For the first time, action potentials were recorded with the use of microelectrodes from myocardial cells beating spontaneously which were obtained by trypsination of guinea-pig embryonic hearts. 4-5 weeks old embryos have been found most suitable for such experiments. The development of cultures and the recordings obtained were compared to those observed in rat hearts under the same experimental conditions. These results showed that inspite of the known physiological differences between adult rat hearts and adult guinea-pig hearts, the cardiomyoblasts cultured under the same conditions possess common features relating to the repolarization phase of action potential, specially a lack of the plateau.
D000200:Action Potentials; D000818:Animals; D002478:Cells, Cultured; D005318:Fetal Heart / Q000502:physiology*; D006168:Guinea Pigs; D008564:Membrane Potentials; D010828:Physiology, Comparative; D051381:Rats
Activité électrique des cellules en culture de coeur de cobaye. Comparaison avec le rat