[Effect of practolol on experimental hypertension in dogs].
In the dog, the intra-venous injection of practolol (1 to 3 mg/kg) reduces the hypertension provoked by vagotomy and sino-aortic nerves section, or by intra-venous administration of potassium cyanide. But practolol differs from propranolol ; he does not modify hypertension observed after electrical stimulation of central end of saphene, laryngeal superior, or vagus nerf.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002339:Carotid Arteries; D002346:Carotid Sinus / Q000502:physiology; D003486:Cyanides; D004285:Dogs; D004562:Electrocardiography; D005260:Female; D005267:Femoral Nerve / Q000502:physiology; D005930:Glossopharyngeal Nerve / Q000502:physiology; D006973:Hypertension / Q000139:chemically induced / Q000188:drug therapy*; D007823:Laryngeal Nerves / Q000502:physiology; D008297:Male; D010791:Phrenic Nerve / Q000502:physiology; D011217:Practolol / Q000627:therapeutic use*; D011433:Propranolol / Q000494:pharmacology; D014630:Vagus Nerve / Q000502:physiology
D003486:Cyanides; D011433:Propranolol; D011217:Practolol
Effets du practolol sur des hypertensions expérimentales chez le chien