Autoantibodies in myasthenia gravis: demonstration of anti-motor endplate antibody and anti-muscle membrane antibody using membrane immunofluorescence technique.
The presence of specific serum antibodies in five myasthenia gravis patients was demonstrated against the motor endplates and muscle membranes of rats by membrane immunofluorescence technique. The immunologic specificity of the antibodies was confirmed. The clinical significance is discussed.
D000818:Animals; D001323:Autoantibodies / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D006801:Humans; D008566:Membranes / Q000276:immunology; D009045:Motor Endplate / Q000276:immunology*; D009132:Muscles / Q000276:immunology*; D009157:Myasthenia Gravis / Q000276:immunology*; D009469:Neuromuscular Junction / Q000276:immunology*; D013934:Thymectomy
D001323:Autoantibodies