title: [Mechanism of the action of acetylsalicyclic acid on formed element aggregation].
abstract: Acetyl-salicylic acid has been found to inhibit the aggregation of erythrocytes and thrombocytes stimulated by proteolytic enzymes (fibrinolysin and trypsin) and phospholipase A. It hampers their hydrolytic action on phospholipids of the blood cells membranes, prevents deformation of the latter under the effect of aggregating agents and also averts a fall of the ATP-ase activity of the erythrocytes membranes caused by parachlormercury-benzoate.
mesh_terms: D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors; D001241:Aspirin / Q000494:pharmacology*; D002729:Chloromercuribenzoates / Q000494:pharmacology; D004347:Drug Interactions; D004789:Enzyme Activation / Q000187:drug effects; D004903:Erythrocyte Aggregation / Q000187:drug effects*; D005341:Fibrinolysin / Q000494:pharmacology; D006801:Humans; D006868:Hydrolysis; D008851:Micropore Filters; D010740:Phospholipases / Q000494:pharmacology; D010974:Platelet Aggregation / Q000187:drug effects*; D013696:Temperature; D013997:Time Factors; D014357:Trypsin / Q000494:pharmacology
chemical_list: D002729:Chloromercuribenzoates; D010740:Phospholipases; D014357:Trypsin; D005341:Fibrinolysin; D000251:Adenosine Triphosphatases; D001241:Aspirin
vernacular_title: Mekhanizm deĭstviia atsetilsalitsilovoĭ kisloty na agregatsiiu formennykh élementov.