[Acute interstitial nephritis with oliguric renal failure following phenylbutazone medication].
Acute oliguric renal failure due to acute interstitial nephritis developed in a patient after treatment with phenylbutazone. The histological, immuno-histological and serological features in this case are compatible with the involvement of a delayed hypersensitivity reaction in the pathogenesis of this drug-induced interstitial nephritis. Other side effects of phenylbutazone on the kidney and the water and electrolyte metabolism are discussed.
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000328:Adult; D001416:Back Pain / Q000188:drug therapy; D004342:Drug Hypersensitivity / Q000150:complications; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed; D007668:Kidney / Q000473:pathology; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000473:pathology; D009846:Oliguria / Q000139:chemically induced; D010653:Phenylbutazone / Q000009:adverse effects* / Q000627:therapeutic use
D010653:Phenylbutazone
Akute interstitielle Nephritis mit oligurischem Nierenversagen nach Phenylbutazon-Medikation.