Effect of chronic alloxan diabetes and insulin administration on intestinal brush border enzymes.
Brush border sucrase and lactase activities are significantly elevated in alloxan-induced chronic diabetes and are restored to control levels after insulin treatment. Alkaline phosphatase and Mg-ATPase levels remain unchanged in diabetes, compared to a control group. Insulin treatment alone to control animals also led to enhanced activities of these enzymes.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology*; D005696:Galactosidases / Q000378:metabolism*; D007328:Insulin / Q000494:pharmacology; D007413:Intestinal Mucosa / Q000201:enzymology*; D008297:Male; D051381:Rats; D013393:Sucrase / Q000378:metabolism*; D001616:beta-Galactosidase / Q000378:metabolism*
D007328:Insulin; D000469:Alkaline Phosphatase; D005696:Galactosidases; D001616:beta-Galactosidase; D013393:Sucrase; D000251:Adenosine Triphosphatases