[Characteristics of contact activation of rabbit blood (kallikrein and plasmin systems].
In vitro experiments showed that caoline-induced contact activation of the kallikreine-kinine system and streptokinase-induced activation of plasmin could possibly occur in rabbit blood plasma. Preliminary short-term treatment of plasma with chloroform removed the factor, inhibiting the two mentioned activation processes. The results obtained provided an indirect evidence for the existence of a functional relationship between the kallikreine and plasmin systems of the blood at the level of the initial step of their activation, i.e. the Hageman factor.
D000818:Animals; D001920:Bradykinin / Q000097:blood; D002725:Chloroform / Q000494:pharmacology; D004950:Esterases / Q000097:blood; D005174:Factor XII; D005341:Fibrinolysin; D006801:Humans; D007610:Kallikreins / Q000097:blood*; D007616:Kaolin / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D013300:Streptokinase / Q000494:pharmacology
D007616:Kaolin; D002725:Chloroform; D005174:Factor XII; D004950:Esterases; D013300:Streptokinase; D007610:Kallikreins; D005341:Fibrinolysin; D001920:Bradykinin
Osobennosti kontaktnoĭ aktivatsii kallikreinovoĭ i plazminovoĭ sistem krovi krolika