Human-mouse mixed lymphocyte cultures.
Conditions for stimulating human lymphocytes with mouse cells are established. The proliferative and cytotoxic responses generated are shown to be specific for antigens coded for in the major histocompatibility locus.
D000818:Animals; D000936:Antigen-Antibody Complex; D002460:Cell Line; D003602:Cytotoxicity, Immunologic; D006649:Histocompatibility Antigens; D006801:Humans; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000276:immunology*; D051379:Mice; D008815:Mice, Inbred Strains; D009374:Neoplasms, Experimental / Q000276:immunology; D013154:Spleen / Q000166:cytology / Q000276:immunology
D000936:Antigen-Antibody Complex; D006649:Histocompatibility Antigens