[Na-K-ATPase activity in the normal aging crystalline lens and in senile cataract].
Activity of Na-K-ATPase decreases in normal bovine and human lens with age. In senile cataract this tendency continues to some extent. In most lenses, clear or opaque, the presence of an inhibitor to Na-K-ATPase can be demonstrated. Its activity which is not influenced by a dialysis, seems to vary greatly. So it is impossible for the moment being to draw conclusions on this special point, except perhaps a certain increase of the inhibition during aging.
D000251:Adenosine Triphosphatases / Q000032:analysis* / Q000037:antagonists & inhibitors; D000328:Adult; D000368:Aged; D000375:Aging; D000818:Animals; D002386:Cataract / Q000201:enzymology* / Q000378:metabolism; D002417:Cattle; D006801:Humans; D007908:Lens, Crystalline / Q000201:enzymology* / Q000378:metabolism; D008875:Middle Aged; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism
D012964:Sodium; D000251:Adenosine Triphosphatases; D011188:Potassium
L'activité Na-K-ATPasique dans le cristallin normal viellissant et dans la cataracte sénile