title: Digitalis in clinical practice.
abstract: Rational use of digitalis requires adequate knowledge of the drug, the disease and the patient, and an ability to integrate these factors. The pharmacology of digitalis is reviewed and the pathophysiology of cardiac failure and supraventricular arrhythmias, as well as aspects of toxicity and the use of serum levels, is discussed. Emphasis is placed on individualisation of therapy and on careful clinical observation.
mesh_terms: D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D001281:Atrial Fibrillation / Q000188:drug therapy / Q000503:physiopathology; D004071:Digitalis Glycosides / Q000097:blood / Q000506:poisoning / Q000627:therapeutic use*; D006321:Heart / Q000503:physiopathology; D006333:Heart Failure / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D009206:Myocardium / Q000201:enzymology
chemical_list: D004071:Digitalis Glycosides; D000251:Adenosine Triphosphatases