Oxyphenbutazone-induced goitre.
A woman who had taken oxyphenbutazone for 4 years because of back pain presented with goitre and hypothyroidism. This was shown to be due to an organification defect, caused or aggravated by oxyphenbutazone.
D001416:Back Pain / Q000188:drug therapy; D005260:Female; D006042:Goiter / Q000139:chemically induced*; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced*; D008875:Middle Aged; D010113:Oxyphenbutazone / Q000009:adverse effects* / Q000627:therapeutic use
D010113:Oxyphenbutazone