[The experimental study of the tolerance to suture materials in the sclerocorneal zone of the globe (author's transl)].
The problem of tissue reaction to the presence of sutures in the sclerocorneal zone has been studied experimentally in 60 rabbit eyes. The suture material used was 6/0 thickness produced By Braun/Melsungen, R.F.A. with nontraumatic needles, silk, non-chromic and chromic catgut, and biosutures prepared from rat tails according to the technique of the Filatov Institute in Odessa (U.S.S.R.). Following non-chromic catgut and the biosuture the tissue reaction was generally very mild but they reabsorbed rapidly. By contrast chromic catgut provoked an intensive reaction and absorbed more slowly with the possibility of producing a toxo-allergic reaction. The silk sutures behaved in the same way as the biosutures and the non chromic catgut. If after 11 or 14 days the silk sutures were not eliminated necrotic changes  developed over them more intensively and the suture fell out. This situation could provoke the formation of fistulae.
D000818:Animals; D002921:Cicatrix; D003315:Cornea / Q000166:cytology / Q000601:surgery*; D011817:Rabbits; D012590:Sclera / Q000166:cytology / Q000601:surgery*; D013537:Sutures; D014945:Wound Healing
Etude expérimentale de la tolérance des matériaux de suture dans la zone limbique du globe oculaire.