Structure-activity studies of methylnitrosourea antitumor agents with reduced murine bone marrow toxicity.
D000478:Alkylation; D000818:Animals; D001853:Bone Marrow / Q000187:drug effects*; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D004273:DNA, Neoplasm / Q000096:biosynthesis / Q000378:metabolism; D005690:Galactose / Q000031:analogs & derivatives / Q000494:pharmacology; D005947:Glucose / Q000031:analogs & derivatives / Q000494:pharmacology; D066298:In Vitro Techniques; D007939:Leukemia L1210 / Q000188:drug therapy*; D008297:Male; D008770:Methylnitrosourea / Q000009:adverse effects / Q000031:analogs & derivatives / Q000494:pharmacology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009363:Neoplasm Proteins / Q000378:metabolism; D009607:Nitrosourea Compounds / Q000494:pharmacology*; D012334:RNA, Neoplasm / Q000378:metabolism; D013311:Streptozocin / Q000031:analogs & derivatives / Q000494:pharmacology; D013329:Structure-Activity Relationship
D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; D009607:Nitrosourea Compounds; D012334:RNA, Neoplasm; D013311:Streptozocin; D008770:Methylnitrosourea; D005947:Glucose; D005690:Galactose