[Active transport of calcium in thymocytes].
Calcium uptake was studied on thymocytes from rabbits with 45Ca loading followed by rapid filtration. Datta shown that the substrates of the mitochondrial electron transport chain did not allowed calcium uptake. Exogenous ATP was required to observe a large influx of calcium in thymocytes. Succinate, magnesium and phosphate ions increased this ATP induced influx of calcium, which was not completely inhibited with atractyloside or ruthenium red.
D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D001278:Atractyloside / Q000494:pharmacology; D001693:Biological Transport, Active; D002118:Calcium / Q000378:metabolism*; D008274:Magnesium / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects; D010710:Phosphates / Q000494:pharmacology; D011817:Rabbits; D012402:Rotenone / Q000378:metabolism / Q000494:pharmacology; D012430:Ruthenium Red / Q000494:pharmacology; D013386:Succinates / Q000378:metabolism / Q000494:pharmacology; D013950:Thymus Gland / Q000187:drug effects / Q000378:metabolism*
D010710:Phosphates; D013386:Succinates; D012402:Rotenone; D012430:Ruthenium Red; D001278:Atractyloside; D000255:Adenosine Triphosphate; D008274:Magnesium; D002118:Calcium
Transport actif du calcium dans les thymocytes