[Glucose role in regulation of placental lactogen hormone (hPL) secretion].
The authors have studied the role of glucose on the excretion of hPL in the medium by explants of placenta in culture. 1. The glucose is necessary for this excretion and cannot be replaced by lactate. 2. At concentrations higher than 1.5 g/l, the glucose inhibits the excretion of hPL. 3. This inhibition is shown for long periods of action of the glucose (4 days) as well as for short periods (1, 2 and 4 hours).
D004305:Dose-Response Relationship, Drug; D005260:Female; D005947:Glucose / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D010920:Placenta / Q000187:drug effects* / Q000378:metabolism; D010928:Placental Lactogen / Q000378:metabolism*; D011247:Pregnancy; D013997:Time Factors
D010928:Placental Lactogen; D005947:Glucose
Rôle du glucose dans la régulation de la sécrétion de l'hormone lactogène placentaire (hPL).