[In vivo assay of antisomatotropic activity of somatostatin and two of its analogs].
Somatostatin (Growth hormone release inhibiting hormone or somatotrophin-release inhibiting factor) and its analogues can be measured in vivo by inhibiting the pentobarbital induced growth hormone release in male rats. Experimental conditions must be carefully defined to become optimal.
D000818:Animals; D013006:Growth Hormone / Q000097:blood*; D008297:Male; D010424:Pentobarbital / Q000494:pharmacology; D051381:Rats; D013004:Somatostatin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D013004:Somatostatin; D013006:Growth Hormone; D010424:Pentobarbital
Dosage in vivo de l'activité antisomatotrophine de la somatostatine et de deux de ses analogues.