title: [Cardiovascular signs in drepanocytosis. Apropos of 12 cases].
abstract: Sickle cell disease is the commonest of the haemoglobinopathies. The pathophysiology consists on the one hand of chronic haemolytic anaemia whose course is punctuated by acute crises with pain, fever and severe haemolysis, and on the other of a tendency to microthrombotic accidents. Of all the very varied clinical features of the disease, cardiac signs are both common and variable. The authors report a series of 92 cases, and compare their findings with those in the literature.
mesh_terms: D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000175:diagnosis*; D006332:Cardiomegaly / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D004417:Dyspnea / Q000209:etiology; D004562:Electrocardiography; D005260:Female; D005334:Fever; D006321:Heart / Q000000981:diagnostic imaging; D006326:Heart Auscultation; D006720:Homozygote; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010146:Pain; D011859:Radiography; D012213:Rheumatic Fever / Q000175:diagnosis; D013927:Thrombosis / Q000209:etiology
vernacular_title: Signes cardiovasculaires de la drépanocytose. A propos de 12 cas