[Double-frequency oscillation in the  glycolytic system. Mathematical model].
A mathematical model describing the generation mechanism of double-frequency oscillations in the glycolytic system is proposed. Interaction of two connected glycolytic oscillation generators are put in the basis of this mechanism. It is assumed in the model that the first oscillation generator is formed due to product activation of phosphofructokinase (PFK) with adenosine diphosphate (ADP), while the second one is based on substrate inhibition of glyceraldehydephosphatededhydrogenase (GAPDH) with glyceraldehydephosphate (GAP).
D000244:Adenosine Diphosphate; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases; D006019:Glycolysis; D008433:Mathematics; D008956:Models, Chemical; D010732:Phosphofructokinase-1
D000244:Adenosine Diphosphate; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases; D010732:Phosphofructokinase-1
Dvukhchastotnye kolebaniia v glikoliticheskoĭ sisteme. Matematicheskaia model'