[Depigmentizing effect of a glucocorticoid applied topically to black giunea pig skin].
A 33 p. cent triamcinolone acetonide in DMSO is applied on the skin of black guinea-pig to ascertain its depigmenting potency. Its action is characterised by a marked, but incomplete, reduction of melanocytes in the epidermis and in the hair. A comparison is made with an other previously experimented corticosteroid.
D000287:Administration, Topical; D000818:Animals; D004121:Dimethyl Sulfoxide; D006168:Guinea Pigs; D010858:Pigmentation / Q000187:drug effects*; D012867:Skin / Q000187:drug effects*; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000494:pharmacology*
D014222:Triamcinolone Acetonide; D004121:Dimethyl Sulfoxide
Dépigmentation de la peau du cobaye noir sous l'action d'un gluco-corticoïde topique