title: [Optical microscopic study of the effect of the hypothalamic hormone T.R.H. on certain cell types of rat anterior hypophysis].
abstract: A cytological and optical microscopic study of the anterior lobe of hypohysis in the Wistar adult rat 10, 30 or 60 minutes after intravenous injection of 50 mug of synthetic TRH discloses modifications of thyrotropic cells and prolactin cells. It's possible to recognize a quick degranulation of the prolactin cells (with a maximum at the 10th minute) and a slower degranulation of the thyrotropic cells (perceptible at the 10th minute and very pronounced at the 60th minute). The somatrotopic cells did not show any modification.
mesh_terms: D000818:Animals; D013006:Growth Hormone / Q000096:biosynthesis; D010902:Pituitary Gland / Q000187:drug effects*; D010903:Pituitary Gland, Anterior / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D011388:Prolactin / Q000096:biosynthesis; D051381:Rats; D013961:Thyroid Gland / Q000502:physiology; D013972:Thyrotropin / Q000096:biosynthesis; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology*
chemical_list: D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D013972:Thyrotropin; D013006:Growth Hormone
vernacular_title: Etude, en microscopie photonique, des modifications de certains types cellulaires de l'antéhypophyse du rat sous l'influence de l'hormone hypothalamique T.R.H