The ultrastructural development of the schistosome egg granuloma in mice.
Hepatic granulomas from mice infected with Schistosoma mansoni for periods of 8 weeks to 1 year studied by electron microscopy. The different cell types present in the granulomas suggested that whilst a delayed hypersensitivity response predominated during early stages of infection an Arthus-type reaction associated with delayed hypersensitivity occurred at later stages of infection.
D000818:Animals; D001183:Arthus Reaction; D005260:Female; D006099:Granuloma / Q000209:etiology / Q000473:pathology; D008099:Liver / Q000469:parasitology / Q000648:ultrastructure*; D008109:Liver Diseases, Parasitic / Q000276:immunology / Q000473:pathology*; D008297:Male; D051379:Mice; D010063:Ovum / Q000648:ultrastructure; D012550:Schistosoma mansoni; D012552:Schistosomiasis / Q000276:immunology / Q000473:pathology*