title: [Major objectives of pathogenic therapy of septicemia].
abstract: On the bases of the published data and their own experience the authors outline the context of the functional biochemical alterations that give an orientation in the choice of the major objectives of pathogenic therapy in the course of septicemias. Analysis of the frequency and intensity of these alterations make it possible to establish therapeutical priorities. In this sense it is demonstrated that hyperazotemia, hyperalbuminemia, low alkaline reserve, elevated serum lactate and a decrease in the plasma Na+/K+ ratio are characteristic of septicemia with a state of toxiinfectious shock.
mesh_terms: D000255:Adenosine Triphosphate / Q000627:therapeutic use; D045930:Anabolic Agents / Q000627:therapeutic use; D001639:Bicarbonates / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000209:etiology; D004232:Diuretics / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008659:Metabolic Diseases / Q000209:etiology; D018805:Sepsis / Q000150:complications / Q000188:drug therapy*; D012772:Shock, Septic / Q000209:etiology; D008063:Thioctic Acid / Q000627:therapeutic use; D014883:Water-Electrolyte Imbalance / Q000209:etiology
chemical_list: D045930:Anabolic Agents; D001639:Bicarbonates; D004232:Diuretics; D005938:Glucocorticoids; D008063:Thioctic Acid; D000255:Adenosine Triphosphate; D006493:Heparin
vernacular_title: Objective majore în terapia patogenică a septicemiilor