Electron-beam induced conformation changes in polypeptide layers: an infrared study.
Langmuir-Blodgett type polypeptide monolayers have been irradiated under conditions simulating the hazards of electron microscopic imaging. The damaging effect, i.e. the randomization of the alpha-helical layers, which occurs in the dose range between 50 and 200 e-/nm2, has been monitored by infrered dichroism.
D004583:Electrons; D005971:Glutamates; D008567:Membranes, Artificial; D010455:Peptides; D011487:Protein Conformation; D013055:Spectrophotometry, Infrared
D005971:Glutamates; D008567:Membranes, Artificial; D010455:Peptides