title: [Experimental basis for a new surgical-therapeutic method for duodenal ulcer: gastric mucoslerosis].
abstract: On the basis of studies carried out by chronic experiments in dogs the authors noted, by clinical, chemical, radiological and histological methods, that the chemical sclerosis of the gastric mucosa performed with a sterile, fresh hypertonic solution of glucose at 60%, injected in the sub-mucosa, represents an intervention which is:--physiological, since the sclero-distrophy is achieved of the acid-secreting glands and "targeted" intra-gastric vago-sympathic denervation, while the storage function of the stomach is maintained;--feasible, since it can be easily performed from the technical view point, without hemorrhagic, perforative intra-operatory risks or hepato-renal toxicity;--fiable, since it was constantly accompanied by good clinical and functional results. The radiological examination of the barium passage in the stomach, antrum, pylorus and duodenum is normal.
mesh_terms: D000818:Animals; D001341:Autonomic Nervous System / Q000187:drug effects; D004285:Dogs; D004381:Duodenal Ulcer / Q000628:therapy*; D005753:Gastric Mucosa / Q000187:drug effects; D005947:Glucose / Q000494:pharmacology; D006982:Hypertonic Solutions; D008722:Methods; D012597:Sclerosing Solutions / Q000627:therapeutic use; D012598:Sclerosis / Q000139:chemically induced; D013270:Stomach / Q000294:innervation; D014630:Vagus Nerve / Q000187:drug effects
chemical_list: D006982:Hypertonic Solutions; D012597:Sclerosing Solutions; D005947:Glucose
vernacular_title: Baze experimentale pentru o nouă metodă terapeutică chirurgicală a ulcerului duodenal: mucoscleroza gastrică