[Ultrastructural observations of the effect of nitrogen mustard on human chromosomes].
The authors observed in electronic microscopy the methyl-bis-beta chlorethylamine action (nitrogen mustard) on normal human chromosomes. The effects were obtained in vitro after colchicine blocking and on grids after fixation. The action is remarkable on the fiber and on the chromatid's structure.
D002478:Cells, Cultured; D002842:Chromatids / Q000648:ultrastructure; D002875:Chromosomes / Q000187:drug effects* / Q000648:ultrastructure; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008466:Mechlorethamine / Q000494:pharmacology*
D008466:Mechlorethamine
Observations ultrastructurales de l'effet d'une moutarde à l'azote sur les chromosomes humains