[The pancreatographic effect during pharmacoangiography of the pancreas following the administration of glucagon (author's transl)].
Angiography before and after the administration of Glucagon was performed in 33 adult patients with symptoms suggesting a pancreatic lesion. Preferently the pancreatographic effect was evaluated. The results were compared with those of the angiography following the administration of Secretin and Tolazoline. The pancreatographic effect was visualized in 70% of the patients examined with Glucagon and the rate of visualization of the effect with Secretin and Tolazoline was 60% and 74.5% respectively. The representation of the small vessels could be enhanced with Glugacon only in 15% for the arteries and in 12.5% for the veins, whereas using Secretin and Tolazoline the improvement raised up to 78% of the cases. -- The pancreatographic effect as an additional sign is useful in the differential diagnosis of the chronic pancreatitis (mottled) and the carcinoma of the pancreas (defect or absence of the effect).-- The superselective technique is recommendable. Using this method an improvement of the pancreatographic effect can be achieved already. In pharmacoangiography Tolazoline gives better results than Glucagon.
D000328:Adult; D000368:Aged; D000681:Amylases / Q000097:blood; D000792:Angiography / Q000379:methods*; D004796:Clinical Enzyme Tests; D003937:Diagnosis, Differential; D005260:Female; D005934:Glucagon; D006801:Humans; D008049:Lipase / Q000097:blood; D008297:Male; D010179:Pancreas / Q000098:blood supply*; D010182:Pancreatic Diseases / Q000097:blood / Q000000981:diagnostic imaging*; D010190:Pancreatic Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging; D010195:Pancreatitis / Q000000981:diagnostic imaging; D012633:Secretin; D014043:Tolazoline
D012633:Secretin; D005934:Glucagon; D014043:Tolazoline; D008049:Lipase; D000681:Amylases
Der pankreatographische Effekt bei der Pankreasangiographie nach Verabreichung von Glucagon