title: Seborrhoeic keratoses and carcinoma of the large bowel. Three cases exhibiting the sign of Lester-trélat.
abstract: Three patients who rapidly developed multiple seborrhoeic keratoses and were found to have adenocarcinoma of the large bowel are described. In two cases the discovery of the neoplasm was prompted by skin manifestations.
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis; D000368:Aged; D003110:Colonic Neoplasms / Q000175:diagnosis; D012628:Dermatitis, Seborrheic / Q000150:complications*; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000150:complications*; D007642:Keratosis / Q000150:complications*; D008297:Male; D012004:Rectal Neoplasms / Q000175:diagnosis; D012877:Skin Manifestations