title: Influence of corticosteroids on connective tissue.
abstract: All glucocorticosteroids inhibit growth, regeneration and repair of cellular or intercellular components of dermal connective tissues, when penetrated through the skin barrier. The resulting atrophy is a logical manifestation of the action of these compounds.
mesh_terms: D000287:Administration, Topical; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001284:Atrophy; D002642:Chick Embryo; D003094:Collagen / Q000096:biosynthesis; D003238:Connective Tissue / Q000187:drug effects*; D003875:Drug Eruptions / Q000209:etiology; D005347:Fibroblasts / Q000187:drug effects; D005938:Glucocorticoids; D006854:Hydrocortisone; D008264:Macrophages / Q000187:drug effects; D008407:Mast Cells / Q000187:drug effects; D051381:Rats; D012038:Regeneration / Q000187:drug effects; D012867:Skin / Q000187:drug effects / Q000378:metabolism; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D003094:Collagen; D006854:Hydrocortisone