[The combined effect of supraoptimal temperature and chemotherapeutic preparations on the metabolism of adenylic nucleotides by Staphylococcus aureus].
Comparative investigation of the effect of nitrofurans on the metabolism of adenylic nucleotides of Staphylococcus aureus at 36 degrees and 40 degrees C was made. It was shown that increasing of the cultivation temperature intensified the bacteristatic effect of nitrofurans. The use of nitrofurans at supraoptimal temperature intensified the activity of ATP-ase and considerably decreased the ATP, ADP and increased the AMP of Staphylococcus aureus.
D000227:Adenine Nucleotides / Q000378:metabolism*; D000244:Adenosine Diphosphate / Q000378:metabolism; D000251:Adenosine Triphosphatases / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D005664:Furazolidone / Q000494:pharmacology; D009581:Nitrofurans / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D013696:Temperature
D000227:Adenine Nucleotides; D009581:Nitrofurans; D005664:Furazolidone; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases
Kombinirovannoe vliianie supraoptimal'noĭ temperatury i khimioterapevticheskikh preparatov na obmen adenilovykh nukleotidov u Staphylococcus aureus