title: [Efficacy and tolerance of trimethoprim sulfamoxole combination in childhood (author's transl)].
abstract: CN 3123 was tested in 4 hospitals on 257 children, 218 of whom were included in the evaluation of the success of therapy. It was administered for the treatment of urinary tract infections (n = 125), bronchial infections (n = 24), intestinal infections (n = 25) and ENT infections (n = 37). The results indicated that, with a failure rate of only 7%, the drug was successfully employed. Tolerance to the medicament was good. Vomiting occurred in 7 children (2.7%) and allergic skin reactions were observed in 6 children (2.3%). A comparative study of CN 3123 and Co-trimoxazole showed the same efficacy and tolerance for both medicaments.
mesh_terms: D002648:Child; D002675:Child, Preschool; D004338:Drug Combinations; D003875:Drug Eruptions / Q000209:etiology; D004751:Enteritis / Q000188:drug therapy; D006801:Humans; D007223:Infant; D010038:Otorhinolaryngologic Diseases / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000188:drug therapy; D013423:Sulfamoxole / Q000009:adverse effects / Q000627:therapeutic use*; D014295:Trimethoprim / Q000009:adverse effects / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy; D014839:Vomiting / Q000139:chemically induced
chemical_list: D004338:Drug Combinations; D014295:Trimethoprim; D013423:Sulfamoxole
vernacular_title: -Sulfamoxol--Sllfamoxol-