The in vitro synthesis of 7-hydroxy dehydroepiandrosterone by human mammary tissues.
Normal and tumorous human mammary tissues were incubated in vitro with [7alpha-3H] dehydroepiandrosterone and [7alpha-3H] dehydroepiandrosterone sulphate. Tritium-labelled 7alpha-hydroxy dehydroepiandrosterone was identified as a principal metabolite from four of the five studies with normal tissue and all seven studies with tumorous tissue.
D000107:Acetylation; D001940:Breast / Q000378:metabolism*; D001943:Breast Neoplasms / Q000378:metabolism; D002854:Chromatography, Paper; D003687:Dehydroepiandrosterone / Q000031:analogs & derivatives* / Q000032:analysis / Q000096:biosynthesis; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D010084:Oxidation-Reduction
D003687:Dehydroepiandrosterone