title: Vitamin E deficiency and seizures in animals and man.
abstract: Study of 100 children with grand mal convulsive disorders and 100 medically healthy children of matching age showed significantly lower plasma levels of vitamin E in the former (means 632.2 +/- 17.3 and 822.5 +/- 21.8 micrograms/dl respectively; p less than 0.001). This finding accords with the ability to prevent seizures in rodents by giving alpha-tocopherol before exposing them to a convulsion-inducing environment.
mesh_terms: D000818:Animals; D002648:Child; D002675:Child, Preschool; D002784:Cholesterol / Q000097:blood; D004830:Epilepsy, Tonic-Clonic / Q000097:blood*; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D051381:Rats; D012640:Seizures / Q000517:prevention & control; D014810:Vitamin E / Q000097:blood* / Q000627:therapeutic use; D014811:Vitamin E Deficiency / Q000150:complications*
chemical_list: D014810:Vitamin E; D002784:Cholesterol