title: [Ingestion and NBT reduction capacity of polymorphonuclear leucocytes in trisomy 21 (author's transl)].
abstract: Polymorphonuclear leukocytes of 30 patients suffering from Trisomy 21 between the ages of 3 months and 21 years were examined by means of a modified NBT-test. Ingestion capacity as well as NBT reduction capacity of polymorphonuclear leukocytes showed a decrease in dependence on the age of the patients examined. It is supposed that both disorders are involved in endangering patients with Trisomy 21 by infections.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000276:immunology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009504:Neutrophils / Q000502:physiology*; D009580:Nitroblue Tetrazolium; D010587:Phagocytosis
chemical_list: D009580:Nitroblue Tetrazolium
vernacular_title: Ingestions- und NBT-Reduktionskapazität neutrophiler Granulocyten bei Trisomie 21