title: [Clinical and experimental examination of the resorption capacity of the tympanic cavity mucosa (author's transl)].
abstract: In a clinical examination of 25 patients with a mesotympanic perforation of the ear drum, it was found after the administration of 35 mg pilocarpine hydrochloride in water or in agar gel into the tympanic cavity, that the mucous membrane of the middle ear complex possesses a significant resorption capacity. The salivation curves obtained in these tests displayed exactly the same characteristics as the curves obtained after administration of the same amount of pilocarpine to the nasal and tracheal mucosa. The results of mathematical processing of the salivation curves by computer (Hawlett-Packard 30) are also given in the study.
mesh_terms: D000042:Absorption; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004432:Ear, Middle / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000187:drug effects / Q000378:metabolism; D010033:Otitis Media / Q000378:metabolism; D010862:Pilocarpine / Q000378:metabolism* / Q000494:pharmacology; D012472:Salivation / Q000187:drug effects; D012636:Secretory Rate; D014432:Tympanic Membrane / Q000187:drug effects / Q000378:metabolism*
chemical_list: D010862:Pilocarpine
vernacular_title: Klinische und experimentelle Untersuchungen über die Resorptionsfähigkeit der Paulkenschleimhaut