[Biological assay of hypophyseal gonadotropins in the male rat (statistical study)].
The reproductibility, the experimental and statistical procedures of FSH and LH bioassays are studied. The estrogen pretreatment of animals increases, considerably the responsiveness and reliability of the LH bioassays. FSH levels have been determined, by the methods for parallel line assays, in the pituitary gland of normal rats and three days or seventeen days orchiectomized rats.
D000818:Animals; D001205:Ascorbic Acid / Q000032:analysis; D001681:Biological Assay; D001835:Body Weight / Q000187:drug effects; D002369:Castration; D004967:Estrogens / Q000494:pharmacology; D005260:Female; D005640:Follicle Stimulating Hormone / Q000032:analysis; D006065:Gonadotropins, Pituitary / Q000032:analysis* / Q000494:pharmacology; D007986:Luteinizing Hormone / Q000032:analysis; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010053:Ovary / Q000032:analysis / Q000187:drug effects; D051381:Rats
D004967:Estrogens; D006065:Gonadotropins, Pituitary; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D001205:Ascorbic Acid
Dosage biologique des gonadostimulines hypophysaires chez le rat mâle (étude statistique)