[Immunosuppressive therapy and candidacidal activity of human neutrophils (author's transl)].
Human neutrophils incubated with 8 immunosuppressive agents ingest and kill normally C. albicans and C. pseudotropicalis. It agrees with previous studies of living microorganism phagocytosis. The decreased resistance to infection of patients treated with immunosuppressive agents seems not to be due to impaired granulocyte phagocytosis.
D001770:Blood Bactericidal Activity; D002175:Candida / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000097:blood / Q000494:pharmacology*; D066298:In Vitro Techniques; D009504:Neutrophils / Q000187:drug effects*; D010587:Phagocytosis / Q000187:drug effects
D007166:Immunosuppressive Agents
Agents immunodépresseurs et pouvoir fongicide des polynucléaires neutrophiles humains