title: Gliding edge dislocations in proteins as a mechanism for active ion transport.
abstract: A mechanism for the translocation of ions across biological membranes is proposed in which transconformational changes occur in the membrane-bound ion pump. In particular, it is suggested that such conformational changes are effected by means of the propagation of crystal defects in the form of edge-dislocation glide.
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D001693:Biological Transport, Active; D002118:Calcium / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism*; D004734:Energy Metabolism; D008565:Membrane Proteins / Q000378:metabolism*; D008958:Models, Molecular; D011188:Potassium / Q000378:metabolism; D011487:Protein Conformation; D012964:Sodium / Q000378:metabolism
chemical_list: D008565:Membrane Proteins; D012964:Sodium; D000251:Adenosine Triphosphatases; D011188:Potassium; D002118:Calcium