title: Metabolic clearance rate of dehydroisoandrosterone sulfate. VI. Studies of eclampsia.
abstract: The metabolic clearance rate of dehydroisoandrosterone sulfate (MCRDS) was measured in 11 women during an eclamptic episode, and the subjects were then followed for at least 5 years. The MCRDS was usually decreased in primigravid women with eclampsia. However, in eclamptic primigravid women who later developed essential hypertension and/or recurrent hypertension in subsequent pregnancies the MCRDS was elevated. Also, in multiparous women with chronic essential hypertension plus superimposed eclampsia, the MCRDS was increased to above normal values.
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003687:Dehydroepiandrosterone / Q000378:metabolism*; D004461:Eclampsia / Q000150:complications / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D006666:History of Medicine; D006801:Humans; D006973:Hypertension / Q000209:etiology; D008657:Metabolic Clearance Rate; D010298:Parity; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology
chemical_list: D003687:Dehydroepiandrosterone