Vein surgery during defibrinogenation.
The effect of defibrinogenation on thrombosis after thrombectomy and on the patency of Dacron femoral vein grafts has been studied in dogs. In all experiments the defibrinogenation significantly reduced thrombosis. Bleeding from suture lines and through the Dacron prostheses was not increased.
D000818:Animals; D012103:Batroxobin / Q000008:administration & dosage / Q000627:therapeutic use*; D001807:Blood Vessel Prosthesis; D004285:Dogs; D005268:Femoral Vein / Q000601:surgery*; D005340:Fibrinogen / Q000032:analysis; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D010447:Peptide Hydrolases / Q000627:therapeutic use*; D011093:Polyethylene Terephthalates; D011183:Postoperative Complications / Q000517:prevention & control; D013927:Thrombosis / Q000517:prevention & control / Q000601:surgery; D013997:Time Factors
D011093:Polyethylene Terephthalates; D005340:Fibrinogen; D010447:Peptide Hydrolases; D012103:Batroxobin