title: Fluorochemical resin complexes for use in solvent repellent hand creams.
abstract: A fluorochemical (FC)-resin complex has been developed for use in protective hand creams. Hand creams incorporating this new technology effectively repel solvents and resist their penetration into the skin. The in vitro studies conducted to determine the efficacy of the formulated FC-resin complex include solvent penetration through treated filter paper, solvent repellency on treated pigskin, and penetration of radio tagged sodium lauryl sulfate through treated hairless mouse skin. In vivo studies demonstrate that this new technology does aid in reducing irritation caused by solvent contact.
mesh_terms: D000818:Animals; D003877:Dermatitis, Contact / Q000517:prevention & control*; D009783:Dermatitis, Occupational / Q000517:prevention & control*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D006229:Hand Dermatoses / Q000517:prevention & control*; D006801:Humans; D066298:In Vitro Techniques; D051379:Mice; D012116:Resins, Plant / Q000627:therapeutic use*; D012867:Skin / Q000187:drug effects; D012997:Solvents / Q000009:adverse effects*; D013552:Swine
chemical_list: D003879:Dermatologic Agents; D012116:Resins, Plant; D012997:Solvents