Prolonged curarisation in the presence of renal impairment.
Prolonged curarisation in the presence of renal failure occurred in six cases where pancuronium was used, and one case where alcuronium was used. The cases are presented with a brief review of the literature. Pancuronium must be used with great caution if postoperative reversal problems are to be avoided. Greater use of adjuvants will reduce requirements and may eliminate the problems encountered in renal failure.
D000328:Adult; D000368:Aged; D000443:Alcuronium / Q000009:adverse effects; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000150:complications* / Q000378:metabolism; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D003473:Neuromuscular Nondepolarizing Agents / Q000009:adverse effects* / Q000378:metabolism; D010197:Pancuronium / Q000009:adverse effects; D011183:Postoperative Complications / Q000209:etiology*; D013997:Time Factors
D003473:Neuromuscular Nondepolarizing Agents; D010197:Pancuronium; D000443:Alcuronium