High-pressure liquid chromatographic separation and determination of anomeric forms of streptozocin in a powder formulation.
A high-pressure liquid chromatographic assay for streptozocin in a sterile powder formulation (1.0 g/vial) is described. The method effectively separates the alpha- and beta-anomeric forms of streptozocin. Quantitative results are presented for the drug based on the use of an internal standard and peak height measurements.
D002851:Chromatography, High Pressure Liquid; D011208:Powders / Q000032:analysis; D013237:Stereoisomerism; D013311:Streptozocin / Q000032:analysis* / Q000302:isolation & purification
D011208:Powders; D013311:Streptozocin