[Microspectrophotometric study of the content of various metabolites in cervical cancer].
The composite microspectrophotometric study of the content of DNA, PAS-positive, alcian-positive substances, lipids, and the activity of succinate dehydrogenase and ascorbic acid in the cervical epithelium normally and in cancer tumors showed preinvasive forms of cancer to be characterized by increased polyploidy, content of DNA and lipids, and increased activity of succinate dehydrogenase, and decreased content of glycogen, acid mucopolysaccharides and ascorbic acid. Invasive forms of cancer are characterized by more marked changes in these values.
D000328:Adult; D000368:Aged; D001205:Ascorbic Acid / Q000378:metabolism; D002584:Cervix Uteri / Q000378:metabolism* / Q000473:pathology; D004273:DNA, Neoplasm / Q000378:metabolism; D005260:Female; D006003:Glycogen / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D008875:Middle Aged; D013053:Spectrophotometry / Q000379:methods; D013385:Succinate Dehydrogenase / Q000378:metabolism; D002583:Uterine Cervical Neoplasms / Q000378:metabolism* / Q000473:pathology
D004273:DNA, Neoplasm; D006025:Glycosaminoglycans; D006003:Glycogen; D013385:Succinate Dehydrogenase; D001205:Ascorbic Acid
Mikrospektrofotometricheskoe issledovanie soderzhaniia nekotorykh metabolitov v rakovykh opukholiakh sheĭki matki.