[Effect of surface roughness of polymers on thrombus formation].
Thromboresistant properties of fluoroplast-4, lavsan, polymethylmetacrylate, carbon glass, employed in various devices contacting the blood and presenting different degrees of the surface roughness, were studied. The thromboresistant properties of polymers were judged on the ground of modified methods for determining the blood coagulating time, thromboelastograms, with reference to the prothrombin complex factors concentration, the amount of fibrinogen, heparin blood tolerance, the thrombocytes adhesion index, their splitting and flattening. A higher class of the polymer surface roughness was found to raise the thromboresistant properties of the surface. In case of polymers with high mechanical and strength properties the surface roughness is of greater importance in the genesis of thrombosis than in polymers possessing elastic properties.
D001672:Biocompatible Materials; D001777:Blood Coagulation; D002244:Carbon; D005465:Fluorocarbon Polymers; D005898:Glass; D011093:Polyethylene Terephthalates; D011108:Polymers; D013499:Surface Properties
D001672:Biocompatible Materials; D005465:Fluorocarbon Polymers; D011093:Polyethylene Terephthalates; D011108:Polymers; D002244:Carbon
Vliianie sherokhovatosti poverkhnosti polimerov na tromboobrazovanie.