title: [Observation of the course of leukoplakia in the Larynx (author's transl)].
abstract: During a period of 15 years biopsies of the larynx of 3000 patients were taken out. At 319 patients the first histodiagnosis "Leukoplakia" was made. 10% carcinomas were found out later on grounds of observation of the course and by letter. 7% of these carcinomas occured within 1 year after the first histodiagnosis of "Leukoplakia". The first biopsy of these 7% carcinomas diagnosed as a "Leukoplakia" must be interpreted as a biopsy out of the marginal area of an already existent carcinoma. 3% of the carcinomas developed from the "Leukoplakia" just in the following years.
mesh_terms: D001706:Biopsy; D004847:Epithelial Cells; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D007971:Leukoplakia / Q000473:pathology*; D013997:Time Factors
vernacular_title: Verlaufsbeobachtung der Leukoplakie im Kehlkopf