Variable effects of heart rate on phasic and regional left ventricular muscle blood flow in anaesthetized dogs.
Tachycardia to 240 beats/min in anaesthetized dogs increases coronary blood flow while flow in the left ventricular wall remains homogeneous. An arteriovenous fistula causes subendocardial ischaemia at 120 beats/min but pacing to 180 to 210 beats/min increases subendocardial blood flow by increasing diastolic coronary driving pressure per minute.
D000818:Animals; D001011:Aorta; D001164:Arteriovenous Fistula / Q000503:physiopathology; D016275:Atrial Function; D001794:Blood Pressure; D002564:Cerium Isotopes; D003326:Coronary Circulation; D003331:Coronary Vessels; D004285:Dogs; D004566:Electrodes; D006339:Heart Rate; D008026:Ligation; D010101:Oxygen Consumption; D010138:Pacemaker, Artificial; D011868:Radioisotopes; D012212:Rheology; D012538:Scandium; D013326:Strontium Radioisotopes; D014159:Transducers; D016276:Ventricular Function
D002564:Cerium Isotopes; D011868:Radioisotopes; D013326:Strontium Radioisotopes; D012538:Scandium