[Demonstration of the variations in accessibility or reactivity of mitochondrial SH groups according to the energy status of the mitochondria].
Evidence for energy dependent variations of mitochondrial SH groups accessibility or reactivity was obtained using alkylating agents. These variations are thought to be consecutive to conformational changes affecting some proteins among them the phosphate carrier and the adenylic nucleotide translocator.
D000227:Adenine Nucleotides / Q000378:metabolism; D000477:Alkylating Agents; D000818:Animals; D001692:Biological Transport; D004734:Energy Metabolism; D008930:Mitochondria, Liver / Q000378:metabolism*; D010101:Oxygen Consumption; D010710:Phosphates / Q000378:metabolism; D051381:Rats; D013386:Succinates / Q000378:metabolism; D013438:Sulfhydryl Compounds / Q000378:metabolism*; D013439:Sulfhydryl Reagents
D000227:Adenine Nucleotides; D000477:Alkylating Agents; D010710:Phosphates; D013386:Succinates; D013438:Sulfhydryl Compounds; D013439:Sulfhydryl Reagents
Mise en évidence des variations d'accessibilité ou de réactivité des groupes SH mitochondriaux suivant l'état énergétique des mitochondries.