Influence of spermine on some membrane-disturbing actions.
The influence of spermine on the potassium loss from yeast cells as a consequence of membrane-disturbing actions was investigated. Spermine interfered strongly in the action membrane-active bactericides on yeast cells; this interference resembles the action of certain metal ions. Spermine provides a protection against the positively charged parasosaniline and accomplishes a strong potentiation of the action of the negatively charged sodium dodecyl sulphate.
D002463:Cell Membrane Permeability / Q000187:drug effects*; D009996:Osmotic Fragility / Q000187:drug effects; D011188:Potassium / Q000378:metabolism; D011523:Protoplasts / Q000187:drug effects; D012394:Rosaniline Dyes / Q000494:pharmacology; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000378:metabolism; D012967:Sodium Dodecyl Sulfate / Q000494:pharmacology; D013096:Spermine / Q000494:pharmacology*; D013696:Temperature
D012394:Rosaniline Dyes; D013096:Spermine; D012967:Sodium Dodecyl Sulfate; D011188:Potassium