title: Relapsing polychondritis: review of current status and case report,.
abstract: This communication has attempted to review the present state of published knowledge on the syndrome of relapsing polychondritis. Basic anatomic, physiologic, and biochemical changes in this disorder are summarized and the role of metabolic and immunologic alterations in the pathogenesis discussed. An additional case of relapsing polychondritis is reported, and the clinical features of this case, plus those of 131 previously reported, are reviewed with discussion of present day therapeutic experience and prognosis.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications; D001706:Biopsy; D002358:Cartilage, Articular / Q000473:pathology; D003937:Diagnosis, Differential; D004195:Disease Models, Animal; D005260:Female; D006025:Glycosaminoglycans / Q000096:biosynthesis / Q000172:deficiency; D006801:Humans; D007109:Immunity; D007166:Immunosuppressive Agents; D008297:Male; D008875:Middle Aged; D010447:Peptide Hydrolases / Q000378:metabolism; D011081:Polychondritis, Relapsing / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000235:genetics / Q000276:immunology / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D011379:Prognosis; D012008:Recurrence
chemical_list: D000305:Adrenal Cortex Hormones; D006025:Glycosaminoglycans; D007166:Immunosuppressive Agents; D010447:Peptide Hydrolases