title: [Drugs and drug combinations responsible for cutaneomucosal reactions].
abstract: The drugs and drug combinations responsible for cutaneo-mucosal reactions are very numerous, which explains why this undesireable side effect is the most frequent of all. Multiple pathogenic mechanisms are described: immunoallergic with its different types of reactions, overdosage, idiosyncrasy, drug interactions, etc. The reactions of produced vary from the maculo-papular rash to definitive staining of the skin. A few specific cases have been analyzed: the allergic reactions with penicillins, the photo-toxicity of certain tetracyclines, licheniform eruptions with gold salts or lupus erythematosus with penicillamine. Centralization of pharmacological information is desireable in order to better understand these reactions.
mesh_terms: D004338:Drug Combinations / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000276:immunology; D004342:Drug Hypersensitivity / Q000276:immunology; D004347:Drug Interactions; D006801:Humans; D010406:Penicillins / Q000009:adverse effects; D013754:Tetracyclines / Q000009:adverse effects
chemical_list: D004338:Drug Combinations; D010406:Penicillins; D013754:Tetracyclines
vernacular_title: Médicaments et associations médicamenteuses responsables de réactions cutanéo-muqueuses