Thymoxamine and intraocular pressure.
Topical treatment with 1% thymoxamine produces in rabbit and human eyes a small but real miotic and tension-lowering effect. The latter is more evident using two different models of experimental ocular hypertension in rabbits. In human open-angle glaucoma eyes, tonographic measurements indicate that the outflow facility is left unchanged by the drug.
D000818:Animals; D005901:Glaucoma / Q000188:drug therapy; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008916:Miotics / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D013948:Moxisylyte / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D009883:Ophthalmic Solutions; D011817:Rabbits
D008916:Miotics; D009883:Ophthalmic Solutions; D013948:Moxisylyte