title: Hfr formation by I pilus-determining plasmids in Escherichia coli K-12.
abstract: R483, an atypical, I pilus-determining plasmid, and also R144, a typical one, were shown to suppress the DnaA phenotype by integration into the Escherichia coli chromosome.
mesh_terms: D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial / Q000378:metabolism; D003087:Colicins / Q000096:biosynthesis; D004261:DNA Replication; D004269:DNA, Bacterial / Q000096:biosynthesis / Q000378:metabolism; D004926:Escherichia coli / Q000187:drug effects* / Q000378:metabolism; D009154:Mutation; D010641:Phenotype; D011815:R Factors; D000198:Spectinomycin / Q000494:pharmacology; D013307:Streptomycin / Q000494:pharmacology; D013696:Temperature; D014170:Transformation, Genetic; D014295:Trimethoprim / Q000494:pharmacology
chemical_list: D003087:Colicins; D004269:DNA, Bacterial; D000198:Spectinomycin; D014295:Trimethoprim; D013307:Streptomycin