title: Retroperitoneal germ cell tumors with no apparent testicular involvement.
abstract: Five men with retroperitoneal germ cell tumors and no apparent testicular involvement are described. Each case has a different feature lending support to one of the various theories concerning the origin of these tumors. Patients with such a tumor are best managed without removal or biopsy of either testis. Careful, periodic re-examination of both testes is suggested. Only if a testis subsequently becomes abnormal is its removal indicated.
mesh_terms: D000328:Adult; D001706:Biopsy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004407:Dysgerminoma / Q000175:diagnosis / Q000628:therapy; D005472:Fluorouracil / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D008926:Plicamycin / Q000627:therapeutic use; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis / Q000628:therapy; D013724:Teratoma / Q000175:diagnosis / Q000628:therapy; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000628:therapy; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D003520:Cyclophosphamide; D008926:Plicamycin; D005472:Fluorouracil; D008727:Methotrexate