title: Enzyme activities in human endometrium, myometrium and leiomyomas of the uterus.
abstract: Certain selected enzymes of carbohydrate metabolism were measured in samples of endometrium and myometrium from women who were premenopausal or postmenopausal. In addition, a number of samples of leiomyoma were obtained and assayed. Activities of several enzymes were higher in endometrium from premenopausal women compared to those in postmenopausal women; activities in myometrium were similar regardless of menopausal status. The activities of G6PD, ICD and GPI appeared to be lower in leiomyoma samples versus myometrial samples from premenopausal women; however, these differences were not apparent when enzyme activity was expressed per milligram protein.
mesh_terms: D004717:Endometrium / Q000201:enzymology*; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D007889:Leiomyoma / Q000201:enzymology*; D008593:Menopause; D008598:Menstruation; D009215:Myometrium / Q000201:enzymology*; D010732:Phosphofructokinase-1 / Q000378:metabolism; D010734:Phosphogluconate Dehydrogenase / Q000378:metabolism; D013997:Time Factors; D014594:Uterine Neoplasms / Q000201:enzymology*; D014599:Uterus / Q000201:enzymology*
chemical_list: D007770:L-Lactate Dehydrogenase; D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D010732:Phosphofructokinase-1