[Subacute alcoholic intoxication in rats: effect of an intravenous injection of glucagon or adrenaline].
We have studied the hyperglycemic effect of glucagon (20 microgram/kg) and adrenaline (5 microgram/kg/mn/3 mn) on the rat subjected to a subacute alcoholic intoxication (6,4 g/kg by day during 12 days). The hyperglycemic action of the glucagon is increased while that of the adrenaline slightly decreased. So, the alcoholic intoxication allows to dissociate the both mechanisms of the glycogenolytic action of both hormones. Two hypothesis are brought forward in the discussion.
D000437:Alcoholism / Q000503:physiopathology*; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D004837:Epinephrine / Q000494:pharmacology*; D000431:Ethanol; D005934:Glucagon / Q000494:pharmacology*; D006801:Humans; D006943:Hyperglycemia / Q000139:chemically induced*; D007700:Kinetics; D008297:Male; D051381:Rats
D001786:Blood Glucose; D000431:Ethanol; D005934:Glucagon; D004837:Epinephrine
Intoxication alcoolique subaiguë chez le rat: action d'une injection intraveineuse de glucagon ou d'adrénaline.