title: Cholestatic hepatitis after administration of furan derivatives.
abstract: A patient developed cholestatic hepatitis while being treated with nitrofurantoin. A second episode of jaundice followed the intravaginal administration of a mixture of furazolidone and nifuroxime. It is important to consider possible cross-sensitivity of chemically related compounds even when they are administered by different routes.
mesh_terms: D000328:Adult; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D002779:Cholestasis / Q000139:chemically induced*; D048909:Diabetes Complications; D003875:Drug Eruptions / Q000209:etiology; D005260:Female; D006801:Humans; D009582:Nitrofurantoin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D014552:Urinary Tract Infections / Q000188:drug therapy
chemical_list: D009582:Nitrofurantoin