title: How toxic are phenols?
abstract: How toxic are phenols? The phenolic acids cannot all be detoxified. Phenyl-glucuronide, although water soluble, can still disturb cell membrane transport mechanisms. Apprecialbe amounts of toxic-free phenols form a lipid pool in the uremic patient. These findings are also relevant to hepatic coma.
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D001692:Biological Transport; D001711:Biotransformation; D004912:Erythrocytes / Q000378:metabolism; D005965:Glucuronates / Q000378:metabolism; D006801:Humans; D062385:Hydroxybenzoates / Q000378:metabolism; D007668:Kidney / Q000378:metabolism*; D007674:Kidney Diseases / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008297:Male; D010636:Phenols / Q000378:metabolism*; D010974:Platelet Aggregation; D051381:Rats; D012457:Salicylamides / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D014511:Uremia / Q000097:blood / Q000378:metabolism*
chemical_list: D005965:Glucuronates; D062385:Hydroxybenzoates; D010636:Phenols; D012457:Salicylamides; D012964:Sodium; D000251:Adenosine Triphosphatases