title: Comparison of therapeutic efficacy of doxycycline, chlortetracycline and lincomycin-spectinomycin on E. coli infection of young chickens.
abstract: Three replicate trials were conducted with broiler male chicks to test the therapeutic efficacy of doxycycline, chlortetracycline and lincomycin-spectinomycin in water against an artifically induced Escherichia coli infection. Mortality, lesion scores (heart, liver and air sac), and performance data were the criteria in evaluating therapeutic efficacy of these drugs. Results indicated the therapeutic efficacy of doxycycline was greater than chlortetracycline and lincomycin-spectinomycin.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002645:Chickens; D002751:Chlortetracycline / Q000008:administration & dosage / Q000627:therapeutic use*; D004318:Doxycycline / Q000008:administration & dosage / Q000627:therapeutic use*; D004927:Escherichia coli Infections / Q000188:drug therapy* / Q000662:veterinary*; D008034:Lincomycin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D011201:Poultry Diseases / Q000188:drug therapy*; D000198:Spectinomycin / Q000008:administration & dosage / Q000627:therapeutic use*; D014867:Water
chemical_list: D014867:Water; D000198:Spectinomycin; D008034:Lincomycin; D004318:Doxycycline; D002751:Chlortetracycline