[Changes in calcium ion binding and characteristics of Na+, K+-ATPase functioning in erythrocytes in the presence of hypertension].
A greater amount of calcium is removed with the aid of EDTA from the erythrocyte membranes of patients with hypertensive disease than from erythrocytes of persons with a normal arterial blood pressure. When isotonic MgCl2 was used the amount of calcium removed from the erythrocytic membrane was equal in both groups. The activity of Na-K-ATP-ase in the membrane of reconstituted erythrocytes increased with the action of calcium ions in the patients with hypertensive disease only half as much as in healthy persons.
D000251:Adenosine Triphosphatases / Q000097:blood*; D000328:Adult; D000368:Aged; D001665:Binding Sites; D002118:Calcium / Q000097:blood*; D002462:Cell Membrane / Q000378:metabolism; D004492:Edetic Acid; D004912:Erythrocytes / Q000201:enzymology / Q000378:metabolism*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000201:enzymology; D008274:Magnesium; D008297:Male; D008875:Middle Aged
D004492:Edetic Acid; D000251:Adenosine Triphosphatases; D008274:Magnesium; D002118:Calcium
Izmenenie sviazyvaniia ionov kal'tsiia i osobennosti funktsionirovaniia Na+, K+-ATFazy v éritrotsitakh pri gipertonicheskoĭ bolezni.