Synthesis and activation of mitotic Ca2+-adenosinetriphosphatase during the cell cycle of mouse mastocytoma cells.
The activity of a Ca2+-adenosinetriphosphatase (ATP phosphohydrolase, EC 3.6.1.3) increases during the mitotic phase of synchronized mouse mastocytoma P-815X2 cells. The enzyme is synchronized mouse mastocytoma P-815X2 cells. The enzyme is synthesized mainly during a distinct period of the interphase and is activated at mitosis. It is thought to regulate the formation of the mitotic apparatus by controlling the concentration of Ca2+ ions at the site of formation of the mitotic spindle.
D000251:Adenosine Triphosphatases / Q000096:biosynthesis / Q000378:metabolism*; D002118:Calcium / Q000494:pharmacology*; D002455:Cell Division; D002460:Cell Line; D004261:DNA Replication; D004789:Enzyme Activation; D012515:Mast-Cell Sarcoma / Q000201:enzymology*; D008938:Mitosis; D014176:Protein Biosynthesis; D013997:Time Factors
D000251:Adenosine Triphosphatases; D002118:Calcium