High-fibre, low-saturated-fat diet and the aetiology of colo-rectal carcinomata in a low-risk population.
The Chilean population exhibits a very low risk for colo-rectal cancer. The farm workers have a high-fibre, low-saturated-fat diet and also an extremely low age-adjusted death rate for colonic and rectal cancer, in each sex. A highly significant positive correlation between age-adjusted death rates from arteriosclerotic heart disease in males and colonic and rectal cancer death rates suggests that high levels of saturated fats and/or cholesterol in the diet may be incriminated for high death rates from large bowel cancer. It is concluded that high plant fibre content and low levels of saturated fats and/or cholesterol in the diet may be important factors influencing the very low age-adjusted death rates from colo-rectal carcinoma in Chilean farm workers.
D002482:Cellulose; D002677:Chile; D002791:Cholesterol, Dietary; D003110:Colonic Neoplasms / Q000453:epidemiology*; D004032:Diet; D004041:Dietary Fats; D005224:Fats, Unsaturated; D005260:Female; D006801:Humans; D008297:Male; D012004:Rectal Neoplasms / Q000453:epidemiology*
D002791:Cholesterol, Dietary; D004041:Dietary Fats; D005224:Fats, Unsaturated; D002482:Cellulose