Inner ear morphology in Down's syndrome.
A comparative study was made on four pairs of temporal bones from patients with Down's syndrome (trisomy 21) and 15 pairs of temporal bones from other infants of the same age range. Spiral reconstructions showed chochlear length to be slightly shorter in temporal bones from patients with Down's syndrome than that in the controls. Based upon these dimensional measurements, a developmental anomaly of the vestibular apparatus was found.
D003051:Cochlea / Q000473:pathology; D004314:Down Syndrome / Q000473:pathology*; D004431:Ear, External / Q000473:pathology; D007758:Ear, Inner / Q000473:pathology*; D004432:Ear, Middle / Q000473:pathology; D006801:Humans; D007223:Infant; D009925:Organ of Corti / Q000473:pathology; D013701:Temporal Bone / Q000473:pathology; D014722:Vestibule, Labyrinth / Q000473:pathology