[Effect of thyrocalcitonin on the functions of the intact and hypertrophied myocardium].
Examination of 20 individuals without any pathological conditions of the cardiovascular system and 8 patients with myocardial hypertrophy has shown that the hypocalciemic hormone of the thyroid gland thyrocalcitonin has a certain negative inotropic effect and does not possess chrono- and dromotropic affects. The mechanism of the cardiac effect of thyrocalcitonin is evidently due to its effect on the metabolism of calcium and its transportation in the myocardial structures.
D000328:Adult; D000368:Aged; D002116:Calcitonin / Q000627:therapeutic use*; D006332:Cardiomegaly / Q000188:drug therapy* / Q000503:physiopathology; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000187:drug effects* / Q000502:physiology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D013997:Time Factors
D002116:Calcitonin
Vliianie tirokaltsitonina na funktsii intaktnogo i gipertrofirovannogo miokarda.