Methotrexate inhibition of CCRF-CEM cultures of human lymphoblasts.
D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D004273:DNA, Neoplasm / Q000096:biosynthesis; D003841:Deoxycytidine / Q000494:pharmacology; D003857:Deoxyuridine / Q000378:metabolism; D005467:Floxuridine / Q000494:pharmacology; D005493:Folic Acid Antagonists; D006801:Humans; D007042:Hypoxanthines / Q000378:metabolism / Q000494:pharmacology; D002955:Leucovorin / Q000494:pharmacology; D007945:Leukemia, Lymphoid / Q000378:metabolism*; D008727:Methotrexate / Q000494:pharmacology*; D011687:Purines / Q000096:biosynthesis; D013936:Thymidine / Q000096:biosynthesis / Q000378:metabolism / Q000494:pharmacology
D004273:DNA, Neoplasm; D005493:Folic Acid Antagonists; D007042:Hypoxanthines; D011687:Purines; D005467:Floxuridine; D003841:Deoxycytidine; D002955:Leucovorin; D013936:Thymidine; D003857:Deoxyuridine; D008727:Methotrexate