title: Plasma hormone levels in different ethnic populations of women.
abstract: It has been suggested that the urinary hormone profile is subject to environmental changes, such as urbanization and Westernization, and that the composition of the hormones can be used as a discriminate in determining the patient at risk for breast cancer. In this study, a comparison of the plasma hormone levels in Bantu and Japanese women, low-risk populations, and Caucasian women, a high-risk population, showed a higher level of 17 beta-estradiol in prepubertal girls and young Bantu and Japanese women. The higher estrogen level in the Bantu was evident in the early luteal and late follicular phases of the menstrual cycle. The difference in the dehydroepiandrosterone and testosterone levels in Bantu young women and prepubertal Bantu girls, suggests differences in adrenal activity between Bantu and Caucasian women. A fall in the plasma androstenedione was evident in postmenopausal Bantu and Japanese but not Caucasian women. Data suggest that the hormone profile is different among the 3 ethnic groups in both the pre- and postmenopausal women. Since the daily life-style of the women is comparable, it is suggested that the composition of the hormone profile is partially dependent on dietary on dietary factors.
mesh_terms: D000311:Adrenal Glands / Q000502:physiology; D000328:Adult; D000349:Africa; D000735:Androstenedione / Q000097:blood; D000818:Animals; D044466:Asian People; D044383:Black People; D001943:Breast Neoplasms / Q000453:epidemiology / Q000209:etiology; D002642:Chick Embryo; D002648:Child; D003687:Dehydroepiandrosterone / Q000097:blood; D004032:Diet; D004958:Estradiol / Q000097:blood; D004967:Estrogens / Q000097:blood; D004970:Estrone / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn; D007564:Japan; D007986:Luteinizing Hormone / Q000097:blood; D008593:Menopause; D008598:Menstruation; D044469:Racial Groups; D013739:Testosterone / Q000097:blood; D044465:White People
chemical_list: D004967:Estrogens; D012739:Gonadal Steroid Hormones; D004970:Estrone; D013739:Testosterone; D000735:Androstenedione; D003687:Dehydroepiandrosterone; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone