[The action of instilled physostigmine on the acetylcholine content of the bovine ciliary body (author's transl)].
The authors have compared the content of acetylcholine (ACh) of the two ciliary bodies (150 microgram of tissue) after the instillation of a stimulating dose of a 1% aqueous solution of physostigmine (10 applications of three drops at intervals of three minutes) into the conjunctival fornix of one eye. Kymographic measurements on guinea-pig ileum demonstrated an average elevation of the ACh content in the instilled ciliary bodies (0.48 microgram) against the controls (0.33 micron). The eyes were enucleated one hour after the last application.
D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D002417:Cattle; D002924:Ciliary Body / Q000187:drug effects / Q000378:metabolism*; D003228:Conjunctiva; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects; D007734:Kymography; D010830:Physostigmine / Q000008:administration & dosage / Q000494:pharmacology*
D010830:Physostigmine; D000109:Acetylcholine
Action de la physostigmine instillée sur le taux d'acétylcholine du corps ciliaire des bovins.