title: Echocardiographic abnormalities in acute rheumatic fever.
abstract: The echocardiographic velocity of circumferential fiber shortening and left atrial dimension were measured serially in two groups of children with acute rheumatic fever: Group I, six patients with valve regurgitation without congestive heart failure, and Group II, seven patients with regurgitation and congestive heart failure. In Group I, the initial velocity of circumferential fiber shortening was increased to 1.90 +/- 0.31 circumferences per second (circ/sec) (mean +/- standard deviation). In group II, it was decreased (1.18+/-0.25). In group I velocity of circumferential fiber shortening subsequently decreased but remained above the normal level; in Group II it increased to exceed the expected normal value. Concurrent changes in left atrial dimension were observed in both groups. The initial left atrial dimension of Group I (2.2 +/- 0.75 cm/m2) was slightly increased and returned to normal (1.70 +/- 0.32) on follow-up study. The left atrial dimension of Group II was greatly increased initially (2.70 +/- 0.81 cm/m2) and remained large (2.50 +/- 0.67). Three patients in Group II experienced rebound during corticosteroid withdrawal. In each the velocity of circumferential fiber shortening decreased, suggesting impaired cardiac contractility. The echocardiogram thus facilitates serial assessment of the severity of carditis in acute rheumatic fever.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000494:pharmacology; D006332:Cardiomegaly / Q000503:physiopathology; D002648:Child; D004452:Echocardiography; D004548:Elasticity; D006325:Heart Atria / Q000503:physiopathology; D006333:Heart Failure / Q000503:physiopathology; D006337:Heart Murmurs; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000503:physiopathology; D009200:Myocardial Contraction / Q000187:drug effects; D010490:Pericardial Effusion; D012213:Rheumatic Fever / Q000503:physiopathology*; D012214:Rheumatic Heart Disease / Q000503:physiopathology
chemical_list: D000305:Adrenal Cortex Hormones