title: [Mixed lymphocyte culture (MLC) as a histocompatibilty test for allogen grafts. Part I: HLA-D locus: genetics and typing (author's transl)].
abstract: The importance of the HLA-gene complex is discussed and, in particular, of the HLA-D locus with respect to the clinical outcome of allografts. The genetic situation is deduced from an evaluation of population and family studies using the mixed lymphocyte culture (MLC). Further methods for the typing of gene products of HLA-D or closely-linked loci are described.
mesh_terms: D000328:Adult; D000483:Alleles; D000936:Antigen-Antibody Complex; D000937:Antigen-Antibody Reactions; D002648:Child; D005260:Female; D006680:HLA Antigens / Q000302:isolation & purification*; D006650:Histocompatibility Testing / Q000379:methods*; D006720:Homozygote; D006801:Humans; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000276:immunology; D014184:Transplantation, Homologous
chemical_list: D000936:Antigen-Antibody Complex; D006680:HLA Antigens
vernacular_title: Die gemischte Lymphozytenkultur (MLC) als Parameter für der Verträglichkeit von allogenen Organtransplantaten. Teil I: Genetische Grundlagen und Möglichkeiten der HLA-D-Typisierung.