[Absence of 5 alpha-reductase in plasma membranes of the hypothalamus in male rats].
No 5alpha-reductase activity was found in plasmic membranes from male rats hypothalami. Contrary to all expectation, it was found that 5alpha-dihydrotestosterone which was synthetized in microsomes or nuclei, was accumulated in plasmic membranes. The significance of this fact is at the moment unknown.
D000728:Androgens / Q000378:metabolism*; D000734:Androstenediols / Q000378:metabolism; D000735:Androstenedione / Q000378:metabolism; D000818:Animals; D002462:Cell Membrane / Q000201:enzymology; D013196:Dihydrotestosterone / Q000378:metabolism; D007031:Hypothalamus / Q000201:enzymology*; D008297:Male; D010088:Oxidoreductases / Q000378:metabolism*; D051381:Rats; D013739:Testosterone / Q000378:metabolism
D000728:Androgens; D000734:Androstenediols; D013196:Dihydrotestosterone; D013739:Testosterone; D000735:Androstenedione; D010088:Oxidoreductases
Sur l'absence de 5alpha-réductase dans les membranes plasmiques de l'hypothalamus du Rat mâle.