title: Clinical significance of skin lesions in the diagnosis of gastrointestinal malignancies.
abstract: Distinctive syndromes correlating skin manifestations and gastrointestinal malignancies are described. The skin lesions may precede, accompany, or follow the primary disease in the gastrointestinal tract and can be important diagnostic clues. They should alert the physician to the possibility that his patient may have an associated internal cancer.
mesh_terms: D000052:Acanthosis Nigricans / Q000175:diagnosis; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis*; D006801:Humans; D007417:Intestinal Polyps / Q000175:diagnosis; D007645:Keratoderma, Palmoplantar / Q000175:diagnosis; D008303:Malignant Carcinoid Syndrome / Q000175:diagnosis; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis; D009808:Odontogenic Tumors / Q000175:diagnosis; D010016:Osteoma / Q000175:diagnosis; D012877:Skin Manifestations; D012878:Skin Neoplasms / Q000175:diagnosis; D013577:Syndrome