title: [Fractional content of androgens in the urine of young sexually mature, old and castrated dogs].
abstract: Fractional composition of 17-KS was studied experimentally in the urine of young sexually-mature, old and castrated dogs. A reduction of the dehydroepiandrosterone, androsterone, ethiocholanolone and of the fraction of 11-oxidized 17-KS in the old, and particularly in the castrated dogs was demonstrated. Androsterone and ethiocholanolone  fractions were subject to the greatest reduction in excretion in the animals under study; the androsterone/ethiocholanolone coefficient was decreased more in old dogs than in the castrated ones. A relative prevalence of dehydroepiandrosterone and of 11-oxdized ketosteroids was noted.
mesh_terms: D000375:Aging; D000728:Androgens / Q000652:urine*; D000738:Androsterone / Q000652:urine; D000818:Animals; D002369:Castration; D003687:Dehydroepiandrosterone / Q000652:urine; D004285:Dogs; D005043:Etiocholanolone / Q000652:urine; D006801:Humans
chemical_list: D000728:Androgens; D003687:Dehydroepiandrosterone; D005043:Etiocholanolone; D000738:Androsterone
vernacular_title: Fraktsionnoe sedershanie androgenov v moche molodykh polovozrelykh, starykh i kastrirovannykh sobak