Erythrocyte enzymes in myelomatosis.
The activity of the erythrocyte enzymes: glucose-6-phosphate dehydrogenase, pyruvate kinase, glutathion reductase and ATPase were measured in 8 patients with untreated myelomatosis. Glucose-6-phosphate dehydrogenase was significantly increased. Glucose-6-phosphate dehydrogenase values were negatively correlated with the glomerular filtration rate as measured by 51Cr-EDTA clearance. The results support the existence of a shortened red cell survival in peripheral blood related to the degree of renal insufficiency.
D000251:Adenosine Triphosphatases / Q000097:blood*; D004912:Erythrocytes / Q000201:enzymology*; D005919:Glomerular Filtration Rate; D005954:Glucosephosphate Dehydrogenase / Q000097:blood*; D005980:Glutathione Reductase / Q000097:blood*; D006801:Humans; D009101:Multiple Myeloma / Q000201:enzymology*; D011770:Pyruvate Kinase / Q000097:blood*
D005954:Glucosephosphate Dehydrogenase; D005980:Glutathione Reductase; D011770:Pyruvate Kinase; D000251:Adenosine Triphosphatases