[The isoenzyme pattern of lactate-dehydrogenase in nasal secretions (author's transl)].
In the present study, the qualitative and quantitative isoenzyme pattern of lactate-dehydrogenase (LDH) in nasal secretions of 52 probands without disease in the nose is investigated electrophoretically. It was found that the LDH-isoenzyme pattern in nasal secretions does not only differ clearly from the distribution of LDH-isoenzymes is serum of the same probands but is characterized especially by a high percentage of LDH 3- and LDH 4-fractions; this corresponds to the monomeres H2M2 and HM3. These results differ completely from any other enzymatic pattern in the human organism. The results clearly indicate that LDH in nasal secretion is a product of the mucous membranes and does not originate from the serum by means of transsudation into the nasal secretion.
D006801:Humans; D007527:Isoenzymes / Q000032:analysis*; D007770:L-Lactate Dehydrogenase / Q000032:analysis*; D009093:Mucus / Q000201:enzymology*; D009297:Nasal Mucosa / Q000201:enzymology / Q000378:metabolism*
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
Das Isoenzymmuster der Laktatdehydrogenase im Nasensekret