The activity of Golgi-membrane galactosyltransferase in the liver of streptozotocin-diabetic rats.
The Golgi-rich membrane fraction isolated from streptozotocin-diabetic rat liver had a lower protein content than the corresponding fraction from normal liver. Its UDPgalactose-N-acetylglucosamine galactosyltransferase activity calculated per 1 g of liver or whole liver was decreased. The electron-microscopic examination of the negatively stained fraction revealed morphological changes. The morphology of the Golgi complex in thin sections of diabetic liver was also changed.
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology* / Q000473:pathology; D005260:Female; D005700:Galactosyltransferases / Q000032:analysis*; D006056:Golgi Apparatus / Q000201:enzymology* / Q000648:ultrastructure; D008099:Liver / Q000201:enzymology* / Q000648:ultrastructure; D012313:RNA / Q000032:analysis; D051381:Rats; D013311:Streptozocin
D013311:Streptozocin; D012313:RNA; D005700:Galactosyltransferases