title: Genetic differences in the levator ani muscle weight between inbred and congenic mouse strains.
abstract: Significant differences in relative weight of the levator ani muscle (LAW) between inbred and congenic mouse strains, differing genetically only by the major histocompatibility H-2 complex were found. It is assumed that a genetic factor (Hom-1), identical or closely associated wi th the H-2 complex, is one of the genes which influence LAW. These experiments suggest that for assay methods for myotropic activity of androgens groups of animals may be used with a homogenous genotype.
mesh_terms: D045930:Anabolic Agents / Q000494:pharmacology; D000818:Animals; D002369:Castration; D005815:Genetic Code; D005838:Genotype; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains / Q000378:metabolism / Q000502:physiology; D024510:Muscle Development; D009132:Muscles / Q000033:anatomy & histology / Q000378:metabolism; D009929:Organ Size; D013739:Testosterone / Q000378:metabolism
chemical_list: D045930:Anabolic Agents; D013739:Testosterone