title: [Lethal aspergillosis of the paranasal sinuses (author's transl)].
abstract: A 73-year-old farmer developed both blindness of his left eye and a 20 kg loss of weight within 3 months. A protrusion of his left eyebulb was observed, which suggested the retrobulbar growth of a tumor. Histologic examinations of several biopsies from the paranasal sinuses evidenced polypoid tissue with signs of chronic inflammation, ulceration, and fungus infection. The patient died in cerebral coma. The autopsy revealed a destruction of the cranial base by a chronic mycocenic osteomyelitis, a frontal lobe abscess, and a fungus invasion of the internal carotid artery with circumscribed thrombosis of this vessel and adjacent encephalomalazie. The fungus was identified morphologically as aspergillus, a rare differential diagnosis to paranasal malignancies.
mesh_terms: D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis*; D001922:Brain Abscess / Q000473:pathology; D002341:Carotid Artery Thrombosis / Q000175:diagnosis; D002343:Carotid Artery, Internal / Q000473:pathology; D003937:Diagnosis, Differential; D005625:Frontal Lobe / Q000473:pathology; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000473:pathology; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis; D010256:Paranasal Sinuses / Q000473:pathology; D012141:Respiratory Tract Infections / Q000175:diagnosis* / Q000000981:diagnostic imaging; D012886:Skull / Q000473:pathology; D014056:Tomography, X-Ray
vernacular_title: Letale Aspergillose der Nasennebenhöhlen