title: [Leukoplakia simplex or metaplastic keratosis of the mouth mucosa?].
abstract: Leukoplakia simplex lesions affecting the oral mucous membrane of cheeks and the floor of the mouth were characterized from the clinical, histological, electron-microscopical and stereological point of view. An integration of the various observations suggested that a combination of atrophic and metaplastic processes give rise to this type of leukoplakia-lesion which imitates epidermal structures and, therefore, could be defined as a metaplastic keratosis. Possible pathogenetic mechanisms are formulated which might be responsible for and cause this type of oral mucous membrane lesion.
mesh_terms: D000328:Adult; D000368:Aged; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007642:Keratosis / Q000473:pathology*; D007971:Leukoplakia / Q000473:pathology*; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology* / Q000648:ultrastructure
vernacular_title: Leukoplakia simplex, oder metaplastische Keratose der Mundschleimhaut?