Congenital lobar emphysema.
Congenital lobar emphysema is reported occurring in a 10 day old, low birth weight infant. Following resection, gross examination of the affected lobe revealed collapsed but unobstructed bronchi, suggesting a cartilaginous defect. The specimen was insufflated with formalin and the bronchial tree dissected out. Histological study including comparison with a normal pulmonary lobe, confirms that abnormalities of cartilage may be important in the pathogenesis of congenital lobar emphysema.
D002356:Cartilage / Q000473:pathology; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D011013:Pneumonectomy; D011656:Pulmonary Emphysema / Q000151:congenital* / Q000473:pathology / Q000601:surgery