title: Spectinomycin modification. III Chloro-deoxy analogs.
abstract: 9-Epichloro-9-deoxy-4(R)-dihydrospectinomycin (3), 9-chloro-9-deoxy-4(R)-dihydrospectinomycin (7), 9-deoxy-8, 9-epimino-4(R)-dihydrospectinomycin (6), and 9-epichloro-9-deoxy-spectinomycin (10) have been prepared and their structures established by proton magnetic resonance. These analogs are devoid of antibiotic activity.
mesh_terms: D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D000198:Spectinomycin / Q000031:analogs & derivatives* / Q000494:pharmacology
chemical_list: D000198:Spectinomycin