Glucose transport-deficient mutant of Neurospora crassa with an unusual rhythmic growth pattern.
A new mutant of Neurospora crassa has been isolated from the patch strain. The phenotype of the new mutant includes the periodic production of sparse and dense aerial hyphae and the inability to utilize carbohydrates. The biochemical lesion was identified as a deficiency in the low-affinity glucose transport system. The high-affinity transport system appeared normal. External conditions such as medium composition, temperature change, and light-dark cycles affected the rhythm of hyphal production to a different extent in the mutant from that in the parental strain. The lesion in the mutant was mapped on the far left arm of linkage group IV.
D000085:Acetates / Q000378:metabolism; D001089:Arabinose / Q000378:metabolism; D001693:Biological Transport, Active; D002250:Carbon Radioisotopes; D002458:Cell Fractionation; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D003470:Culture Media; D003513:Cycloheximide / Q000494:pharmacology; D003624:Darkness; D008040:Genetic Linkage; D005947:Glucose / Q000031:analogs & derivatives / Q000378:metabolism*; D005990:Glycerol / Q000378:metabolism; D008928:Mitochondria / Q000201:enzymology; D009154:Mutation; D009491:Neurospora / Q000378:metabolism*; D009492:Neurospora crassa / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism*; D010507:Periodicity; D010641:Phenotype; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism; D013696:Temperature
D000085:Acetates; D002250:Carbon Radioisotopes; D003470:Culture Media; D011768:Pyruvate Dehydrogenase Complex; D003513:Cycloheximide; D001089:Arabinose; D005947:Glucose; D005990:Glycerol