[Blood lactic acid level changes during acidosis induced by hydrochloric acid perfusion].
An increase in H+ ions concentration by infusion of hydrochloric acid produces a reduction in lactacidemia. This phenomenon is a result of the inhibitory effect of acidosis on phosphofructokinase producing a diminution of intracellular glycolysis.
D000136:Acid-Base Equilibrium / Q000187:drug effects; D000138:Acidosis / Q000097:blood* / Q000139:chemically induced; D000818:Animals; D004285:Dogs; D006400:Hematocrit; D006454:Hemoglobins / Q000378:metabolism; D006851:Hydrochloric Acid; D007773:Lactates / Q000097:blood*; D010100:Oxygen / Q000097:blood; D011773:Pyruvates / Q000097:blood
D006454:Hemoglobins; D007773:Lactates; D011773:Pyruvates; D006851:Hydrochloric Acid; D010100:Oxygen
Variations de la lactacidémie au cours de l'acidose induite par perfusiond'acide chlorhydrique