Contact sensitization to benzoyl peroxide.
Four formulations of benzoyl peroxide, two 5% and two 10% gels, were assayed for contact sensitizing capability by the human maximization test. Seventy-six per cent became sensitized. Sensitized subjects reacted to all four formulations. Benzoic acid and related compounds failed to elicit an allergic reaction.
D000152:Acne Vulgaris / Q000188:drug therapy; D001585:Benzoyl Peroxide / Q000009:adverse effects* / Q000627:therapeutic use; D003875:Drug Eruptions / Q000209:etiology*; D006801:Humans; D010328:Patch Tests; D010545:Peroxides / Q000009:adverse effects*
D010545:Peroxides; D001585:Benzoyl Peroxide