Protective effects of adenosine triphosphate administration in burns.
The effects of intramuscular adenosine triphosphate (ATP) administration after thermal skin injury on the ATP content and morphology of the liver and heart were studied in male Sprague-Dawley rats. The results showed that exogenous ATP injected during the early post-burn period could restore the ATP content of the liver and heart to near normal values and modify the burn-related morphological alterations in the liver.
D000251:Adenosine Triphosphatases / Q000008:administration & dosage* / Q000378:metabolism / Q000627:therapeutic use; D000818:Animals; D002056:Burns / Q000188:drug therapy* / Q000473:pathology; D004341:Drug Evaluation; D007273:Injections, Intramuscular; D007274:Injections, Intraperitoneal; D008099:Liver / Q000201:enzymology / Q000473:pathology; D009206:Myocardium / Q000201:enzymology / Q000473:pathology; D051381:Rats
D000251:Adenosine Triphosphatases