Studies on the vesicular component of the Auerbach's plexus and the substance P content of the mouse colon in the acute phase of the experimental Trypanosoma cruzi infection.
A dramatic reduction in the total number of dense vesicles in Auerbach's plexus of the mouse colon was observed during the acute phase of experimental American Trypanosomiasis (Chagas' disease). A significant decrease in substance P activity of the colon of inoculated animals was also measured. It is suggested that this decrease in substance P activity could be related to the reduction in the number of dense vesicles in Auerbach's plexus.
D000818:Animals; D014355:Chagas Disease / Q000378:metabolism / Q000473:pathology*; D003106:Colon / Q000032:analysis* / Q000648:ultrastructure; D008297:Male; D051379:Mice; D008854:Microscopy, Electron; D009197:Myenteric Plexus / Q000648:ultrastructure*; D013373:Substance P / Q000032:analysis*; D013997:Time Factors
D013373:Substance P