The changes of in vitro 131I-iodine uptake in the thyroid gland of rats exposed to septal lesions and immobilization stress.
The in vitro uptake of 131I by the thyroid gland was investigated in rats after immobilization stress with special respect to animals lesioned in the septal area. Lesions in a septal area performed 10 days before decreased the iodide accumulation in the thyroid, while stress by immobilization increased it to the control basal value. Repeated immobilization in control rats did not produce any changes in the iodide uptake in vitro. ACTH injected in vivo stimulated the iodide 131I uptake in vitro by thyroid glands of hypophysectomized rats. It is concluded that immobilization stress in rats with septal lesions increases 131I-iodide uptake in vitro and that the increase was probably influenced by both catecholamines and glucocorticoids.
D000818:Animals; D007016:Hypophysectomy; D007103:Immobilization; D066298:In Vitro Techniques; D007455:Iodine / Q000378:metabolism*; D007457:Iodine Radioisotopes; D008297:Male; D051381:Rats; D013312:Stress, Physiological / Q000378:metabolism*; D013961:Thyroid Gland / Q000378:metabolism*
D007457:Iodine Radioisotopes; D007455:Iodine