[The proteincomposition of human parotid saliva in acute and chronic parotitis. Quantitativ densitometry of single protein-fractions in comparison to normal secretions].
By means of acrylamidgelectrophoresis parotid secretions of patients with acute and chronic parotitis were examined. Thereby significant changes in protein patterns of electrophoretic separation were found. Especially two bands are described in detail. One in the cathodal near gel region, the isoamylases, and the otherone in the anodal part of the gel, identified as albumin. In rest and under stimulation these bands show signficant changes compared to normal secretions. Furthermore information about the capacity of the parotid gland parenchyma is won by observing the changes of amylase bands in rest and under stimulation in chronic parotitis without actute exacerbations. The amylase shows a remarked decreased secretion in chronic parotitis under stimulation corresponding to parenchymalteration. The same happens with the albuminexcretion as parameter for ductlesions. In chronic parotitis albmuninexcretion goes parallel to duct changes in sialography. Therefore by discelectrophoretic separation of native parotid saliva a helpful mean for diagnostic use is given, besides sialography and scintigraphy.
D000208:Acute Disease; D000418:Albumins / Q000032:analysis; D002908:Chronic Disease; D003720:Densitometry; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007517:Isoamylase / Q000032:analysis; D010309:Parotitis / Q000000981:diagnostic imaging / Q000378:metabolism*; D011506:Proteins / Q000032:analysis*; D012463:Saliva / Q000378:metabolism*; D012796:Sialography
D000418:Albumins; D011506:Proteins; D007517:Isoamylase
Uber die Proteinzusammensetzung des menschlichen Parotissekretes bei akuten und chronischen Entzüdungen Quantitative denistometrische Bestimmung der einzelnen Proteinfraktionen im Vergleich zu normalen Drüsensekreten