title: [Change in the content of T-and B-lymphocytes in experimental benzene poisoning (author's transl)].
abstract: Changes in T-and B-lymphocytes content in experimental benzene intotication (BI) of CBA-mice were studied. The content of spontaneously rosette-forming cells, B-lymphocytes with C3 -receptors and T-cells in macro-and microtest was determined. It was shown that BI resulted in disorders in the function of thymus, depression of T-cell system and autoimmune shifts. A number of characteristics in kinetics of various fractions of lymphoid cells due perhaps, to different sensitivity of particular types of lymphoid cells to benzene and compensatory response as well. The significance of described phenomena is discussed.
mesh_terms: D000818:Animals; D000961:Antilymphocyte Serum; D001402:B-Lymphocytes / Q000276:immunology*; D001554:Benzene / Q000506:poisoning*; D002452:Cell Count; D008198:Lymph Nodes / Q000166:cytology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D012397:Rosette Formation; D013154:Spleen / Q000166:cytology; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland / Q000166:cytology
chemical_list: D000961:Antilymphocyte Serum; D001554:Benzene
vernacular_title: Veränderungen des T-und B-Lymphozytengehalts bei experimenteller Benzolintoxikation.