title: [Immunosuppressive activity of several drugs and their effect on antibody formation in pullorum disease].
abstract: Furazolidon given alone or in combination with chloramphenicol, with spectinomycin, with gentamycin or with sodium arsenilate as well as chlorpyrazine, applied alone, suppress the clinical manifestation of pullorum disease in birds both in the experimental and in the spontaneous outbreak of the disease. These medicinal drugs lower the production of agglutinins in birds--mostly the combination furazolidon+chloramphenicol, followed by furazolidon+sodium arsenilate. The same combinations do not prove essentially effective in influencing the development of the morphologic lesions and do not fully exempt the body from the causative agent of pullorum disease.
mesh_terms: D000373:Agglutinins / Q000096:biosynthesis; D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D002645:Chickens; D002701:Chloramphenicol / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005664:Furazolidone / Q000627:therapeutic use; D005839:Gentamicins / Q000627:therapeutic use; D007166:Immunosuppressive Agents; D011201:Poultry Diseases / Q000188:drug therapy*; D012481:Salmonella Infections, Animal / Q000188:drug therapy*; D000198:Spectinomycin / Q000627:therapeutic use
chemical_list: D000373:Agglutinins; D000890:Anti-Infective Agents; D000907:Antibodies, Bacterial; D005839:Gentamicins; D007166:Immunosuppressive Agents; D005664:Furazolidone; D002701:Chloramphenicol; D000198:Spectinomycin
vernacular_title: Imunodepresivna aktivnost na niakoi lekarstva i vliianieto im vurkhu antitialoobrazuvaneto pri tif-pulorozata.