[Hemoglobin Stanleyville II and mucoviscidosis in an Alsatian family].
Hemoglobin Stanleyville II, resembling hemoglobin D, has been found several times in individuals from Central Africa. This paper now reports its discovery in Alsace, in an 8 year old girl with cystic fibrosis. The mother and 5 out of 7 siblings had the abnormal hemoglobin. Only 2 of these 5 children had all the symptoms of cystic fibrosis. The family has been living in Alsace for many generations. Cystic fibrosis, a congenital disease, has a high incidence (1/1,800) among white children but is rare in black people.
D000328:Adult; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications / Q000235:genetics*; D005260:Female; D005602:France; D006453:Hemoglobinopathies / Q000150:complications / Q000235:genetics*; D006455:Hemoglobins, Abnormal; D006579:Heterozygote; D006801:Humans; D008297:Male; D010375:Pedigree; D044465:White People
D006455:Hemoglobins, Abnormal
Hémoglobine Stanleyville II et mucoviscidose dans une famille alsacienne