[The kinetics of the humoral and secretory IgA-production at the beginning of an acute respiratory disease (A.R.D.) in infants (author's transl)].
On three consecutive days at the beginning of an acute respiratory disease (A.R.D.) we analysed the concentration of IgA in the serum and in the aspirate of the nasopharyngeal region (N.P.A.) of 13 infants from the age of 3 up to 21 months (average age: 7.4 months). We found, that the absolute concentration as well as the dynamics of the changes of the concentration were higher in the N.P.A. than in the serum. The differences found are statistically significant. On the basis of these pathophysiological facts a screening-method could be developed for the early diagnosis of acute virus diseases of the upper respiratory passages.
D000914:Antibodies, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007223:Infant; D007700:Kinetics; D008297:Male; D009093:Mucus / Q000276:immunology*; D009305:Nasopharynx; D012141:Respiratory Tract Infections / Q000276:immunology*; D014777:Virus Diseases / Q000175:diagnosis
D000914:Antibodies, Viral; D007070:Immunoglobulin A
Die Kinetik der humoralen und sekretorischen IgA-Produktion im Beginn eines akuten respiratorischen Infektes (A.R.E.) im Säuglings- und Kleinkindesalter.