[Changes in the ATPase activity of the brain and erythrocytes in hypoxia].
An effect of hypoxic hypoxia on the total, Mg2+-dependent and Na-K-dependent ATPase activities was studied in rat brain and erythrocytes. In brain tissue under effect of 15 min hypoxia a distinct decrease in all the ATPase activities was observed; the activity of Na-K-dependent ATPase decreased especially distinctly (by 32% of the initial level). Within 90 min of hypoxia the enzymatic activity was partially restored but did not reach the initial level. In erythrocytes 15 min hypoxia was also accompanied by a significant decrease in Na-K-dependent ATPase activity (30.5% of the initial level). But within 90 min the enzymatic activity was distinctly increased (up to 196.4%). Mg2+-dependent ATP-ase was more resistant to oxygen deficiency, Variations in the enzymatic activity were less distinct, although they showed the same pattern as those of the Na-K-dependent ATPase.
D000251:Adenosine Triphosphatases / Q000032:analysis / Q000378:metabolism*; D000818:Animals; D001273:Atmosphere Exposure Chambers; D001921:Brain / Q000201:enzymology*; D002413:Cations, Divalent; D002414:Cations, Monovalent; D004789:Enzyme Activation; D004794:Enzyme Repression; D004912:Erythrocytes / Q000201:enzymology*; D000860:Hypoxia / Q000201:enzymology*; D008274:Magnesium / Q000378:metabolism; D008297:Male; D011188:Potassium / Q000378:metabolism; D051381:Rats; D012964:Sodium / Q000378:metabolism; D013997:Time Factors
D002413:Cations, Divalent; D002414:Cations, Monovalent; D012964:Sodium; D000251:Adenosine Triphosphatases; D008274:Magnesium; D011188:Potassium
Izmeneniia ATf-aznoĭ aktivnosti mozga i éritrotsitov