title: [On amino acid antagonists: beta-diketoesters and their corresponding gamma-enolethers].
abstract: Starting with well known beta-diketoesters the corresponding gamma-enolethers are synthesized and described. Both classes of compounds inhibited the growth of some microorganisms. The inhibition is abolishable by addition of certain amino acids to the definite medium. A possible mechanism of inhibition is discussed and compared with the mechanism of some beta,gamma-unsaturated alpha-amino acids. The known unsaturated alpha-amino acids, their origin and their biological activity are summarized in two tables.
mesh_terms: D000596:Amino Acids / Q000037:antagonists & inhibitors*; D001419:Bacteria / Q000032:analysis / Q000187:drug effects*; D055598:Chemical Phenomena; D002621:Chemistry; D004952:Esters; D004987:Ethers; D005231:Fatty Acids, Unsaturated; D007651:Keto Acids / Q000494:pharmacology*; D010944:Plants / Q000032:analysis; D013329:Structure-Activity Relationship; D000637:Transaminases / Q000037:antagonists & inhibitors; D015003:Yeasts / Q000187:drug effects*
chemical_list: D000596:Amino Acids; D004952:Esters; D004987:Ethers; D005231:Fatty Acids, Unsaturated; D007651:Keto Acids; D000637:Transaminases
vernacular_title: beta-Diketoester und deren Enoläther als Aminosäure-Antagonisten