Selective activation of human suppressor cells by a nonproliferative stimulus.
The eliciting of suppressor cell activity by heat-treated stimulating cells demonstrates that suppression can be induced by an antigenic but non-effective mixed lymphocyte culture (MLC) stimulus in vitro. Simultaneous or prior MLC or cytotoxic T lymphocyte activity is not required for alloantigen-induced suppressor cell activation.
D000941:Antigens; D002455:Cell Division; D006358:Hot Temperature; D006801:Humans; D007111:Immunity, Cellular; D066298:In Vitro Techniques; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D013601:T-Lymphocytes / Q000276:immunology* / Q000378:metabolism; D013936:Thymidine / Q000378:metabolism
D000941:Antigens; D013936:Thymidine