[Collagen modifications after deep cutaneous burns in rats].
Acid extracted collegen is prepared from rat skin 48 hours after burning ; the material obtained is purified by salt precipitation and fractionnated by carboxymethylcellulose chromatography as described by Piez (3). Control samples are studied by a similar procedure. It can be concluded that after burning, rat skin collagen becomes insoluble ; the result seems to be consistent with intra and intermolecular crosslinks formation.
D000818:Animals; D002056:Burns / Q000378:metabolism*; D003094:Collagen / Q000032:analysis*; D004591:Electrophoresis, Polyacrylamide Gel; D051381:Rats; D012995:Solubility
D003094:Collagen
Modifications du collagène après brûlure cutanée profonde chez le rat.