[Effect of Corynebacterium parvum on the immune response in guinea pigs. II. Passive transfer of enhanced anamnestic response and delayed hypersensitivity observed after treatment with Corynebacterium parvum].
After intradermal immunization with a mixture of Corynebacterium parvum (C. parvum) and ovalbumin guinea pigs show a markedly increased anamnestic response to an intradermal booster of ovalbumin as compared to controls treated with ovalbumin only. At the same time a reaction of delayed type hypersensitivity is observed in the treated animals, but not in controls. The enhanced anamnestic response as well as the posivitive skin reaction were transferred to strain 2 histocompatible guinea pigs by peripheral blood leukocytes as well as by peritoneal exudate cells. Passive transfer was not obtained after prior irradiation of donor animals.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D000907:Antibodies, Bacterial / Q000032:analysis; D000917:Antibody Formation; D001202:Ascitic Fluid / Q000166:cytology; D001803:Blood Transfusion; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed; D007116:Immunization, Passive; D008214:Lymphocytes / Q000276:immunology; D010047:Ovalbumin / Q000276:immunology; D011425:Propionibacterium acnes / Q000276:immunology*; D011830:Radiation Effects
D000906:Antibodies; D000907:Antibodies, Bacterial; D010047:Ovalbumin
Effet du Corynebacterium parvum sur la réponse immune du Cobaye. II. Transfert passif de la réponse anamnestique amplifiée et de l'hypersensibilité retardée obtenue après traitement par le Corynebacterium parvum.