A family with apparently sex-linked optic atrophy.
A family is described in which a probable new form of sex-linked optic atrophy was found in eight individuals. Some additional neurological abnormalities were noted. Results of studies of the Xg blood group excluded close linkage between the optic atrophy and Xg genes. As a probable coincidence, Huntington's chorea was found in a side branch of the family.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001789:Blood Group Antigens; D002648:Child; D002675:Child, Preschool; D005260:Female; D005796:Genes; D008040:Genetic Linkage; D005838:Genotype; D006801:Humans; D006816:Huntington Disease / Q000235:genetics; D008297:Male; D008875:Middle Aged; D009461:Neurologic Manifestations; D009896:Optic Atrophy / Q000175:diagnosis / Q000235:genetics*; D010375:Pedigree; D012730:Sex Chromosomes; D014792:Visual Acuity
D001789:Blood Group Antigens