title: [Activity of phosphofructokinase in some organs of guinea pigs with different ascorbic acid levels].
abstract: Changes of the phosphofructokinase (PFK; KF.2.7.I.II) activity in the skeletal and heart muscle, in the liver and skin of guinea pigs with different ascorbic acid allowances of their organism were studied. In animals receiving physiological and high vitamin "C" doses no changes in the activity of the tissues under study were observed. In cases of acute C-hypovitaminosis the activity of the enzyme in the skin fell by 26 per cent, in scurvy it declined in the liver by 28 per cent and in the skin -- by 46 per cent. In these conditions the PFK activity in the skeletal and heart muscles remained invariable. In one group of the animals chronic latent C-hypovitaminosis was simulated it attended by a diminishing fermentative activity in the heart by 24 and in the skin -- by 20 per cent. No changed activity in the liver was revealed.
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000032:analysis* / Q000378:metabolism / Q000494:pharmacology; D001206:Ascorbic Acid Deficiency / Q000201:enzymology*; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D008099:Liver / Q000201:enzymology; D009132:Muscles / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D010732:Phosphofructokinase-1 / Q000378:metabolism*; D012867:Skin / Q000201:enzymology
chemical_list: D010732:Phosphofructokinase-1; D001205:Ascorbic Acid
vernacular_title: Aktivnost' fosfofruktokinazy v nekotorykh organakh morskikh svinok pri pazlichnoi stepeni obespechennosti askorbinovoĭ kislotoĭ