[Permeability of sublingual mucosa to organic molecules. Limited role of sublingual absorption in aerosol vaccinations].
131I labelled tetanus anatoxin was placed in vivo, in the sublingual area in the rat. The radioactivity appearing in blood was insignificant, even after that the disappearance rate in reference animal had been taken into account. It is concluded that immunisation with aerosols is fundamentally carried out through the respiratory tract.
D000336:Aerosols; D000818:Animals; D001692:Biological Transport; D007275:Injections, Intravenous; D008297:Male; D009060:Mouth Floor / Q000378:metabolism*; D009092:Mucous Membrane / Q000378:metabolism; D051381:Rats; D013745:Tetanus Toxoid / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D013961:Thyroid Gland / Q000378:metabolism; D014611:Vaccination
D000336:Aerosols; D013745:Tetanus Toxoid
La perméabilité de la mugueuse sub-linguale aux molécules organiques. Les limites du rôle de la voie sub-linguale dans la vaccination par aérosols