An outline of D-penicillamine metabolism.
In a study using 14C-D-penicillamine in a normal subject only 50% of the D-penicillamine was absorbed from the gut. The major urinary metabolites are cysteine-penicillamine and penicillamine disulphide. S-methyl-D-penicillamine is the only biochemically transformed metabolite so far identified.
D000596:Amino Acids / Q000652:urine; D001711:Biotransformation; D003545:Cysteine / Q000652:urine; D005243:Feces / Q000737:chemistry; D006207:Half-Life; D006801:Humans; D010396:Penicillamine / Q000737:chemistry / Q000378:metabolism* / Q000493:pharmacokinetics
D000596:Amino Acids; D010396:Penicillamine; D003545:Cysteine