[Hyperbaric oxygen: effect of sodium dipropylacetate and dipropylacetamine on convulsion seizures and pulmonary lesions in the mouse].
It was shown that oxygen at high pressure (OHP) induced epileptic seizures and pulmonary damages on mice. Dipropylacetate protected mice against nervous syndrome better than did dipropylacetamide. No significant pulmonary protection was observed with both drugs.
D000081:Acetamides / Q000494:pharmacology; D000818:Animals; D006931:Hyperbaric Oxygenation / Q000009:adverse effects*; D051379:Mice; D011654:Pulmonary Edema / Q000209:etiology / Q000517:prevention & control*; D012640:Seizures / Q000209:etiology / Q000517:prevention & control*; D014631:Valerates / Q000031:analogs & derivatives* / Q000494:pharmacology*; D014635:Valproic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology*
D000081:Acetamides; D014631:Valerates; D014635:Valproic Acid
Oxygène hyperbare: effets du dipropylacétate de Na et du dipropylacétamide sur les crises convulsives et les lésions pulmonaires chez la souris