Effect of zinc and cadmium on delta-aminolevulinate dehydratase of red blood cells in protecting against enzyme losses during storage.
The effect of zinc and cadmium on delta-aminolevulinate dehydratase of bovine erythrocytes stored at -30 degrees C for different times was determined. The results show a. storage of erythrocytes leads to an enhancement of the enzyme activity, which after six weeks is 165% (500 muM ZnCl2) respectively 220% (100 muM CdCl2) for red blood cells of calves, and after four weeks in 420% respectively 450% (same concentrations) for red blood cells of adult cattle, b. the older the samples are, the higher is the metal concentrations, needed for activation.
D000818:Animals; D001793:Blood Preservation; D002104:Cadmium / Q000494:pharmacology*; D002417:Cattle; D004305:Dose-Response Relationship, Drug; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D006836:Hydro-Lyases / Q000097:blood*; D000623:Porphobilinogen Synthase / Q000097:blood*; D015032:Zinc / Q000494:pharmacology*
D002104:Cadmium; D006836:Hydro-Lyases; D000623:Porphobilinogen Synthase; D015032:Zinc