[Influence of temperature on the secretion of insulin and glucagon induced by stimulation of cholinergic receptors in the presence of glucose].
In the presence of a glucose concentration of 1.5 g/1 the secretion of insulin from the isolated perfused rat pancreas is clearly weaker at 28 degrees C than at 37.5 degrees C. In response to cholinergic stimulation, the absolute increase of insulin secretion rate is less at 28 degrees C than at 37.5 degrees C. However, when evaluated in percentage in relation to the baseline value, this increase is more important at the lower temperature. As to glucagon secretion, lowering of the temperature from 37.5 degrees C to 28 degrees C modifies neither this secretion in the presence of glucose alone, nor the increased secretion provoked by the cholinergic stimulation.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D005934:Glucagon / Q000378:metabolism*; D005947:Glucose / Q000494:pharmacology*; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000378:metabolism*; D051381:Rats; D011950:Receptors, Cholinergic / Q000502:physiology*; D013696:Temperature
D007328:Insulin; D011950:Receptors, Cholinergic; D005934:Glucagon; D005947:Glucose; D000109:Acetylcholine
Influence de la température sur les sécrétions d'insuline et de glucagon provoquées par la stimulation des récepteurs cholinergiques en  présence de glucose.