[Action of an ovulation stimulator on the genital function of the female rat].
Effect of cyclofenil on genital function implied organs, is studied in cyclic female rats injected s. cut: 0.5, 5 or 50 mg/kg/day, during 12 days. The treatment increases pituitary, adrenal and uterine weights, decreases ovarian weight, adrenal and ovarien cholesterol. These data suggest that cyclofenil acts directly or undirectly at different levels of hypothalamo-pituitary-genital axis with central inhibition and light peripheral stimulation.
D000311:Adrenal Glands / Q000032:analysis / Q000187:drug effects*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002784:Cholesterol / Q000032:analysis; D003408:Cresols / Q000494:pharmacology*; D003506:Cyclofenil / Q000494:pharmacology*; D004971:Estrus / Q000187:drug effects; D005260:Female; D009929:Organ Size / Q000187:drug effects; D010053:Ovary / Q000032:analysis / Q000187:drug effects*; D010060:Ovulation / Q000187:drug effects; D010870:Pineal Gland / Q000187:drug effects; D010902:Pituitary Gland / Q000187:drug effects*; D011247:Pregnancy; D051381:Rats; D013961:Thyroid Gland / Q000187:drug effects; D014599:Uterus / Q000187:drug effects
D003408:Cresols; D002784:Cholesterol; D003506:Cyclofenil
Action d'un "stimulateur de l'ovulation" sur la fonction génitale de la ratte