The applications of steroid hormone radioimmunoassays to clinical obstetrics.
This is a selective survey of recent publications dealing with theoretical and established applications of steroid hormone radioimmunoassay procedures applied to clinical obstetric investigation. This subject is reviewed in three sections: first, basic principles of steroid hormone radioimmunoassay methodology; second, steroidogenesis in normal pregnancy and its relation to patterns of steroid hormones measured in maternal and fetal circulations; third, applied steroid radioimmunoassay technology as it is being used in established and potential clinical applications. It is concluded that steroid hormone radioimmunoassay procedures have been and will continue to be a highly productive technology applied to clinical obstetric investigation.
D000305:Adrenal Cortex Hormones / Q000096:biosynthesis / Q000097:blood*; D002784:Cholesterol / Q000096:biosynthesis; D003687:Dehydroepiandrosterone / Q000097:blood; D004953:Estetrol / Q000097:blood; D004958:Estradiol / Q000097:blood; D004964:Estriol / Q000097:blood; D004970:Estrone / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005333:Fetus / Q000378:metabolism; D012739:Gonadal Steroid Hormones / Q000096:biosynthesis / Q000097:blood*; D006801:Humans; D006908:Hydroxyprogesterones / Q000097:blood; D008099:Liver / Q000378:metabolism; D010920:Placenta / Q000378:metabolism; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011863:Radioimmunoassay
D000305:Adrenal Cortex Hormones; D012739:Gonadal Steroid Hormones; D006908:Hydroxyprogesterones; D004970:Estrone; D003687:Dehydroepiandrosterone; D004958:Estradiol; D002784:Cholesterol; D004953:Estetrol; D004964:Estriol