Effect of glucose on the utilization of palmitate 1 14C by rat kidney cortex slices.
The authors studied the effect of glucose on the uptake and utilization of palmitate 1 14C by rat kidney cortex slices. They found that its inhibitory effect on free fatty acid (FFA) uptake was caused by inhibition of the incorporation of 1 14C-labelled palmitate into the total lipids and FFA and by reduced oxidation to 14CO2. Glucose has a regulative function in the utilization of FFA by the kidneys.
D000818:Animals; D002250:Carbon Radioisotopes; D002784:Cholesterol / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000037:antagonists & inhibitors; D005947:Glucose / Q000494:pharmacology*; D007672:Kidney Cortex / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D010084:Oxidation-Reduction; D010168:Palmitates / Q000378:metabolism*; D010169:Palmitic Acids / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism; D051381:Rats; D014280:Triglycerides / Q000378:metabolism
D002250:Carbon Radioisotopes; D005230:Fatty Acids, Nonesterified; D010168:Palmitates; D010169:Palmitic Acids; D010743:Phospholipids; D014280:Triglycerides; D002784:Cholesterol; D005947:Glucose