[Excito-motor action of succinyldicholine and other cholinic esters on the spinal cord of the mouse].
We have realized on mice the spinal animal experiment, cutting the spinal chord below the bulb during artificial respiration. We have observed that the cholin esters and particularly the succinyldicholin injected into a caudal vein produce muscular contractions, of which we give a graphic. After having discussed these experimental results, we conclude that every cholin ester has an excitatory effect on the spinal chord. It must now be determined which of these esters is the normal medullary transmitter.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D007275:Injections, Intravenous; D051379:Mice; D010767:Phosphorylcholine / Q000494:pharmacology; D051381:Rats; D013116:Spinal Cord / Q000187:drug effects*; D013390:Succinylcholine / Q000031:analogs & derivatives* / Q000494:pharmacology
D010767:Phosphorylcholine; D013390:Succinylcholine; D000109:Acetylcholine
Action excito-motrice de la succinyldicholine et d'autres esters choliniques sur la moelle épinière de la Souris