title: [A study of a new osmotic anti-glaucoma medication, isosorbide, in ophthalmic surgical practice (author's transl)].
abstract: Study of isosorbide effect in postoperative long term therapy. A preestablished randomized sequence allows one to compare two series of cases, cataract and glaucoma procedures, one series receiving the drug, the other series serving as a control. Based on the following clinical parameters, coaptation of wound edges, depth of anterior chamber, vitreous volume and position, iris position, analysis of the results demonstrates less complications in the treated serie. Efficacy, safety, scarcity of side effects of the drug, allows its prolonged administration in such clinical situations entailing treatment of postoperative ocular hypertension.
mesh_terms: D000368:Aged; D000768:Anesthesia, General; D000772:Anesthesia, Local; D002387:Cataract Extraction; D002648:Child; D004341:Drug Evaluation; D005260:Female; D005901:Glaucoma / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D007547:Isosorbide / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009995:Osmosis; D011183:Postoperative Complications / Q000517:prevention & control; D013012:Sorbitol / Q000031:analogs & derivatives*
chemical_list: D013012:Sorbitol; D007547:Isosorbide
vernacular_title: Etude d'une nouvelle médication osmotique anti-glaucomateuse, l'isosorbide, dans le cadre de la chirurgie oculaire.