[Modification of potassium current by 4 aminopyridine. Case of the isolated giant axon of the cockroach (Periplaneta americana)].
Action of 4-aminopyridine has been studied under voltage-clamp on the isolated giant axon of the cockroach. Our results show that 4-AP reduces K+ currents (inward or outward currents).
D000200:Action Potentials / Q000187:drug effects*; D000588:Amines; D000818:Animals; D001369:Axons / Q000187:drug effects; D002463:Cell Membrane Permeability / Q000187:drug effects*; D003058:Cockroaches; D011188:Potassium / Q000502:physiology*; D011725:Pyridines / Q000031:analogs & derivatives / Q000494:pharmacology*; D013779:Tetrodotoxin / Q000494:pharmacology
D000588:Amines; D011725:Pyridines; D013779:Tetrodotoxin; D011188:Potassium
Modifications des courants potassium par la 4-aminopyridine. Cas de l'axone géant isolé de la blatte (Periplaneta americana)