title: [Serum thyroxine-binding protein for determining the functional state of the thyroid gland in pregnant women with endemic goiter].
abstract: A determination was made of the hormone-forming capacity of the thyroid gland in pregnent women under conditions of goiter endemic at various periods of pregnancy by trimesters (123-in healthy pregnant women, 206-with euthyroid goiter of the I degree, 271-or II degree, 90-of the II degree, and 4-of the IV degree). A method of zonal electrophoresis in the medinal-veronal buffer was applied. Thyrofixin with I131 isotope (made in the USSR) was used. With increase of the periods of pregnancy and the degree of euthyroid hyperplasia of the thyroid gland and goiter the thyroid gland function became elevated irrespective of age.
mesh_terms: D005260:Female; D006043:Goiter, Endemic / Q000097:blood* / Q000503:physiopathology; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D012423:Rural Health; D012426:Russia; D013961:Thyroid Gland / Q000503:physiopathology; D013975:Thyroxine-Binding Proteins / Q000032:analysis*; D014505:Urban Population
chemical_list: D013975:Thyroxine-Binding Proteins
vernacular_title: Tiroksinsviazyvaiushchiĭ belok krovi v opredelenii funktsional'nogo sostoianiia shchitovidnoĭ zhelezy u beremennykh v usloviiakh zobnoĭ ĕndemii