title: [Pathophysiological aspects of therapeutic procedures in Menière's disease (author's transl)].
abstract: Meniére's disease is a nosologic entity. Its underlying pathophysiological mechanism is based on a disturbance of the quantitative correlation between peri- and endolymph volume on the one side and on a qualitative disorder of sodium and potassium concentration in the inner ear fluids on the other, resulting in a disregulation of osmotic pressure within the labyrinth. However, a critical review of the current literature as well as personal observations confirm that at the present time the scientific basis of a causal therapy is still lacking. Hence, both conservative and surgical treatment of Menière's disease does not allow to cure the cause but only some of the symptoms.
mesh_terms: D006801:Humans; D007761:Labyrinthine Fluids / Q000378:metabolism; D008575:Meniere Disease / Q000503:physiopathology* / Q000601:surgery; D008833:Microcirculation; D009994:Osmolar Concentration; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D014882:Water-Electrolyte Balance
chemical_list: D012964:Sodium; D011188:Potassium
vernacular_title: Pathophysiologische Aspekte und therapeutische Möglichkeiten beim Morbus Menière.