Immmune complex glomerular disease in argyric mice.
A mesangiopathic glomerulonephritis with prominent mesangial immunoglobulin deposits was induced in mice by single or multiple intraperitoneal injections of bovine serum albumin. The silver-labelled basement membrane in mice which had ingested 6mM silver nitrate in drinking water proved a useful marker indetermining that the immune deposits were on the intracapillary aspect of the basement membrane.
D000818:Animals; D001129:Argyria / Q000473:pathology*; D001485:Basement Membrane / Q000648:ultrastructure; D005921:Glomerulonephritis / Q000473:pathology*; D007105:Immune Complex Diseases / Q000473:pathology*; D007668:Kidney / Q000473:pathology; D007678:Kidney Glomerulus / Q000648:ultrastructure; D051379:Mice