Metabolic clearance rate of dehydroisoandrosterone sulfate. VI. Studies of eclampsia.
The metabolic clearance rate of dehydroisoandrosterone sulfate (MCRDS) was measured in 11 women during an eclamptic episode, and the subjects were then followed for at least 5 years. The MCRDS was usually decreased in primigravid women with eclampsia. However, in eclamptic primigravid women who later developed essential hypertension and/or recurrent hypertension in subsequent pregnancies the MCRDS was elevated. Also, in multiparous women with chronic essential hypertension plus superimposed eclampsia, the MCRDS was increased to above normal values.
D000328:Adult; D002908:Chronic Disease; D003687:Dehydroepiandrosterone / Q000378:metabolism*; D004461:Eclampsia / Q000150:complications / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D006666:History of Medicine; D006801:Humans; D006973:Hypertension / Q000209:etiology; D008657:Metabolic Clearance Rate; D010298:Parity; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology
D003687:Dehydroepiandrosterone