A model for the assessment of left ventricular compliance: effect of hypertrophy and infarction.
Non-linear elastic theory was applied to the problem of diastolic filling of the left ventricle, which was treated as a thick-walled sphere. The mathematical model was used to predict pressure-volume relationships for ventricles with various initial dimensions and myocardial elasticity constants. A resonable agreement was obtained with data reported in the literature. The results may provide a basis for the use of empirical compliance indices.
D000818:Animals; D001794:Blood Pressure; D002306:Cardiac Volume; D006332:Cardiomegaly / Q000503:physiopathology*; D003187:Compliance; D004285:Dogs; D006321:Heart / Q000502:physiology* / Q000503:physiopathology; D006801:Humans; D008954:Models, Biological; D009203:Myocardial Infarction / Q000503:physiopathology*; D011817:Rabbits; D016276:Ventricular Function