title: [Studies on the state of vitamins B1, B2 and B6 in Down's syndrome].
abstract: In 110 children-between 0-16 years of age-, 90 children with Down-syndrome and 20 controls the following metabolic parameter were analyzed: ETK (vitamin-B1-activating coefficient), EGR (vitamin B2), P-5'-P, EGOT (vitamin B6), GOT, GPT, pH, K, Na, Ca, Cl, uric-acid (HS). Among some important correlations between the different parameters it could be demonstrated-for the first time to our knowledge-that in Mongoloids a disturbance of the vitamin-B1-metabolism exists, certified by the so-called transketolase-test.
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D002648:Child; D004314:Down Syndrome / Q000378:metabolism*; D004573:Electrolytes / Q000378:metabolism; D005260:Female; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D011736:Pyridoxine / Q000378:metabolism*; D012256:Riboflavin / Q000378:metabolism*; D013831:Thiamine / Q000378:metabolism*
chemical_list: D004573:Electrolytes; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D011736:Pyridoxine; D012256:Riboflavin; D013831:Thiamine
vernacular_title: Untersuchungen zum Status von Vitamin B1, B2 und B6 beim Down-Syndrom