Renal hypertrophy in experimental diabetes: relation to severity of diabetes.
Streptozotocin diabetic rats have larger kidneys than non-diabetic rats. In the present study the rate of kidney growth during the first seven days of diabetes was correlated with the blood glucose concentration. Over a wide range of blood glucose concentrations (116-340 mg/100 ml) the kidney weight, protein content and protein/DNA ratio were closely correlated with the glucose values.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D004247:DNA / Q000032:analysis; D003920:Diabetes Mellitus / Q000139:chemically induced; D003928:Diabetic Nephropathies / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006984:Hypertrophy; D007668:Kidney / Q000032:analysis / Q000473:pathology*; D011506:Proteins / Q000032:analysis; D051381:Rats; D013311:Streptozocin
D001786:Blood Glucose; D011506:Proteins; D013311:Streptozocin; D004247:DNA