Elevated lymphocyte ATP-ase activity in patients with cancer of the uterine cervix.
Elevated lymphocyte Adenosine Tri-Phosphatase (ATP-ase) activity was found in 23 och 28 patients with cervical uterine carcinomas of various stages. Treatment with external irradiation and radium insertion was followed by a decline in the lymphocyte ATP-ase activity in 22 patients, while the activity remained unchanged in one patient. No correlation between the tumour stage and the lymphocyte ATP-ase activity was demonstrated. In 24 patients the clinical effect of the treatment was well correlated with the decline in ATP-ase activity. It is suggested that the determination of lymphocyte ATP-ase activity could be valuable in screening for cervical carcinoma and for follow-up after radical treatment.
D000251:Adenosine Triphosphatases / Q000097:blood*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology*; D008875:Middle Aged; D011883:Radium / Q000627:therapeutic use; D002583:Uterine Cervical Neoplasms / Q000201:enzymology* / Q000532:radiotherapy
D000251:Adenosine Triphosphatases; D011883:Radium