[Has N-isopropyl-N'-phenylparaphenylenediamine a place among standard allergens? Importance of this allergen in rubber intolerance].
Allergic contact dermatitis to N-isopropyl-N'-phenylparaphenylenediamine (IPPD) from rubber is far from being exceptional. Out of a total of 56 cases of allergic contact dermatitis to IPPD, 42 were considered as caused by occupational contacts: 17 cases were found in tyre manufacturers, 9 in car-mechanics, 9 in drivers, and 7 in various industrial branches. Out of the 56 cases, 23 also reacted allergically to mercaptobenzothiazole or to tetramethylthiuramdisulphide, or to both of these substances. In a chromatographic analysis of samples of 9 different tyre brands, IPPD was found in 8 cases.
D000485:Allergens; D055598:Chemical Phenomena; D002621:Chemistry; D003877:Dermatitis, Contact; D009783:Dermatitis, Occupational / Q000139:chemically induced*; D006801:Humans; D015122:Mercaptopurine / Q000009:adverse effects; D010655:Phenylenediamines / Q000009:adverse effects*; D012408:Rubber / Q000009:adverse effects*; D013893:Thiram / Q000009:adverse effects
D000485:Allergens; D010655:Phenylenediamines; D013893:Thiram; D012408:Rubber; C014627:N-isopropyl-N-phenyl-4-phenylenediamine; D015122:Mercaptopurine
La N-isopropyl'N'-phénylparaphénylènediamine a-t-elle sa place dans la batterie standard d'allergènes? Importance de cet allergène dans l'intolérance au caoutchouc.