[A new method for technical synthesis of tertiary and quaternary d,1-tropic acid esters of some N-subsituted nortropan- and granatan-3-oles (author's transl)].
A new technically feasible method for synthesizing atropine is described. This method can also be applied to N-substituted nortropan- and granatan-3-oles. The quaternization of these basic tropic acid ester yields new substances which have a pharmacological profile different from that of atropine. The stereoselectivity of the quanternization reaction is discussed.
D001285:Atropine / Q000138:chemical synthesis; D009241:Ipratropium / Q000138:chemical synthesis; D008722:Methods; D008968:Molecular Conformation; D000644:Quaternary Ammonium Compounds / Q000138:chemical synthesis; D014326:Tropanes / Q000138:chemical synthesis*
D000644:Quaternary Ammonium Compounds; D014326:Tropanes; D001285:Atropine; D009241:Ipratropium
Eine neue Methode zur technischen Darstellung von tertiären und quartären d,1-Tropasäureestern einiger N-substituierter Nortropan- bzw. Granatan-3-ole