[Changes in rat hypothalamo-neurohypophyseal system after repeated ethanol administration].
The histochemical, immunohistological and histoenzymatic study of the hypothalamo-neurohypophysial system of the rat shows that chronic ethanol administration induces: a temporary blockage of vasopressin synthesis, a vasoconstriction of the neurohypophysial capillaries, a dendritic storage of immunoreactive vasopressin. In our experimental conditions, a long ethanol treatment disturbs the balance between vasopressin synthesis and release.
D000437:Alcoholism / Q000503:physiopathology*; D000818:Animals; D003712:Dendrites / Q000378:metabolism; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects*; D008297:Male; D010904:Pituitary Gland, Posterior / Q000098:blood supply / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D014667:Vasopressins / Q000096:biosynthesis
D014667:Vasopressins; D000431:Ethanol
Modifications du système hypothalamo-neurohypophysaire du rat après administration répétée d'éthanol