title: Safety of long-term tetracycline therapy for acne.
abstract: Results of blood chemistry studies using an automated multiple analysis system and blood cell counts for 325 patients receiving long-term low-dosage tetracycline hydrochloride therapy continuously for three years or longer revealed minimal changes in all but one patient. This patient developed a transient hyperbilirubinemia with mild juandice while taking 500 mg of tetracycline daily.
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D000368:Aged; D001772:Blood Cell Count; D001774:Blood Chemical Analysis; D002481:Cellulitis / Q000188:drug therapy; D002648:Child; D005260:Female; D005499:Folliculitis / Q000188:drug therapy; D005667:Furunculosis / Q000188:drug therapy; D006801:Humans; D008297:Male; D012393:Rosacea / Q000188:drug therapy; D013752:Tetracycline / Q000009:adverse effects / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D013752:Tetracycline