title: [Radiological determination of skull thickness and skull thickness increase in patients with severe blood dyscrasias and hyperplasia of the red marrow (author's transl)].
abstract: A method is described for measuring the thickness of the cranial bones in x-ray pictures of the skull, which in a reliable way can only be done in the frontal and the parietal bones. From the results, representative and comparable values have been obtained consisting of the mean and maximum thickness of the bones and of the mean deviation of the thickness in the bone. By using these values, the thickness has been determined in normal persons and the increase of thickness established in different patients suffering from a number of blood disorders. A scale of increasing degrees of thickening could be set up ranging form normal conditions to extraordinary enlargement. As the thickening of the bones is due to the hyperactivity of the red marrow contained in the bones, and the increase of thickness depends on the intensity of the overgrowth of the marrow and of the time of its action on the osseous substance, from the thickness of the bones a conclusion can be drawn regarding the presence, the severity and the duration of the existing blood disorder. Since, moreover, the enlargement of the bones is irreversible, an increased thickness of the cranial bones may, in patients without alterations in the blood, point to a former blood disorder.
mesh_terms: D000293:Adolescent; D000328:Adult; D000740:Anemia; D000747:Anemia, Hypochromic; D000755:Anemia, Sickle Cell; D000886:Anthropometry; D001855:Bone Marrow Diseases; D002648:Child; D002675:Child, Preschool; D005260:Female; D005624:Frontal Bone / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010294:Parietal Bone / Q000000981:diagnostic imaging* / Q000473:pathology; D011859:Radiography; D013789:Thalassemia
vernacular_title: Zur röntgenologischen Bestimmung der Dicke der Schädelknochen und ihrer Verbreiterung bei Patienten mit schwerer Bluterkrankung und Hyperplasie des roten Knochenmarks