title: [Fatty acid patterns and glucose tolerance in Huntington's chorea (author's transl)].
abstract: Fatty acid patterns of plasma lipids and glucose-tolerance in Huntington's chorea. 25 patients with Huntington's chorea of various manifestation (9 predisposed symptomefree, 5 with light and 11 with severe manifestation) had studies of carbohydrate and lipid metabolism. These studies measured glucose-tolerance tests, insulin-, HGH-secretion, serum lipids and plasma fatty acid conposition of the cholesterylesters, triglycerides and phospholipids. The reactive insulin- but not HGH-levels were significantly raised, 32 % of the patients with Huntington's chorea had abnormal glucose-tolerance tests, compared with 3.2 % in a control group. Duration of symptoms correlated with higher cholesterol levels. Minor deviations were found in the fatty acid patterns in various lipid clases.
mesh_terms: D002784:Cholesterol / Q000097:blood; D005227:Fatty Acids / Q000097:blood*; D005951:Glucose Tolerance Test; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D006816:Huntington Disease / Q000097:blood*; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D008055:Lipids / Q000097:blood*; D011236:Prediabetic State / Q000097:blood
chemical_list: D005227:Fatty Acids; D007328:Insulin; D008055:Lipids; D013006:Growth Hormone; D002784:Cholesterol
vernacular_title: Fettsäuremuster der Plasmalipide, Insulin- und HGH-Sekretion bei Huntingtonscher Chorea