In vitro parameters of cell-mediated immune reactions in healthy individuals following immune-stimulation attempts with levamisole.
In vitro parameters of cellular immune reactions were followed by 10 healthy individuals during administration of levamisole. Leucocyte migration tests, lymphocyte transformation tests and ATP-ase activity of peripheral blood lymphocytes were investigated. Levamisole did not influence resting human lymphocytes of the stimulation response of lymphocytes. The metabolic activity of lymphocytes expressed by their ATP-ase activity was not significantly changed after levamisole administration.
D000251:Adenosine Triphosphatases / Q000032:analysis; D000328:Adult; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007978:Levamisole / Q000494:pharmacology; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000187:drug effects / Q000201:enzymology / Q000276:immunology; D008297:Male; D013997:Time Factors
D007978:Levamisole; D000251:Adenosine Triphosphatases