title: [Familial pericentric inversion of y chromosome and Down's syndrome].
abstract: A boy with Down's syndrome is presented. Karyotipe showed a 47,XY,+21,inv Y(p+q--) constitution. The father had the same Y anomaly. A review of pericentric inversions of Y chromosome and its possible relation with Down's syndrome is made.
mesh_terms: D002869:Chromosome Aberrations; D002904:Chromosomes, Human, 21-22 and Y; D004314:Down Syndrome / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male
vernacular_title: Inversión pericéntrica familiar del cromosoma Y y síndrome de Down