title: Stimulation of the thalamus and its effect on electrographic manifestations of the brain in unrestrained rats.
abstract: The thalamus was electrically stimulated in unrestrained rats with implanted cortical and subcortical electrodes. Single pulses often triggered rhythmic cortical activity identical with the 8--9/sec spike episodes which occur spontaneously in rats in the walking state. In rhythmic stimulation of the thalamus, self-sustained 3/sec spike-wave paroxysmal activity, with partial clonic jerks, was observed. Specific and non-specific thalamic nuclei participated in the production of these activities.
mesh_terms: D000818:Animals; D001143:Arousal; D001921:Brain / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology; D004558:Electric Stimulation; D004569:Electroencephalography; D005071:Evoked Potentials; D006624:Hippocampus / Q000502:physiology; D008297:Male; D051381:Rats; D013787:Thalamic Nuclei / Q000502:physiology; D013788:Thalamus / Q000502:physiology*