title: [Thallium intoxication treated by hemodialysis, forced diuresis and antidote (author's transl)].
abstract: Mode of action and toxicity of thallium and former treatment of thallium intoxication are described. A case of thallium poisoning with a lethal dose of thallous sulfate which was successfully treated by hemodialysis, forced diuresis and antidote is reported. 43 percent of the thallium could be eliminated by continuous hemodialysis during 72 hours and forced diuresis within the third and seventh day after ingestion of the poison. The dialysance of thallium was 111,1 ml/min with a blood flow of 200 ml/min. Later damage can be prevented by early maximal elimination of thallium.
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000328:Adult; D000931:Antidotes; D004232:Diuretics / Q000627:therapeutic use; D005295:Ferrocyanides / Q000627:therapeutic use; D006801:Humans; D008928:Mitochondria / Q000187:drug effects; D011041:Poisoning / Q000628:therapy*; D006435:Renal Dialysis; D013793:Thallium / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000506:poisoning*
chemical_list: D000931:Antidotes; D004232:Diuretics; D005295:Ferrocyanides; D013793:Thallium; D000251:Adenosine Triphosphatases
vernacular_title: Thalliumvergiftung. Kombinationsbehandlung mit Hämodialyse, forcierter Diurese und Antidot