[Animal experimental studies on the question of chemical prevention of congenital clefts. II. Studies on mouse cleft palates due to cyclophosphamide].
Embryotoxic and teratogenic effects were produced by cyclophosphamide in mice of the AB/Jena-Halle strain. The simultaneous administration of Solcoseryl tended to modify these noxious effects, significantly reducing the incidence of cleft palates to one half.
D000183:Actihaemyl / Q000627:therapeutic use*; D000818:Animals; D002972:Cleft Palate / Q000139:chemically induced / Q000517:prevention & control*; D003520:Cyclophosphamide; D005260:Female; D005333:Fetus / Q000187:drug effects; D051379:Mice; D011247:Pregnancy; D014020:Tissue Extracts / Q000627:therapeutic use*
D014020:Tissue Extracts; D000183:Actihaemyl; D003520:Cyclophosphamide
Tierexperimentelle Untersuchungen zur Frage der medikamentösen Prophylaxe kongenitaler Spaltbildungen.