Depression, ECT, and erythrocyte adenosinetriphosphatase activity.
Erythrocyte membrane Na+-K+ ATPase and Ca++ATPase levels were investigated in 11 women treated with ECT for endogenous depression and 11 age-matched normal control subjects. Pretreatment ATPase levels in depressives were significantly lower than in controls, and increased to control levels after a course of ECT. These data are discussed in terms of the physiology of depressive illness and ECT.
D000251:Adenosine Triphosphatases / Q000097:blood*; D000328:Adult; D001714:Bipolar Disorder / Q000201:enzymology / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D002462:Cell Membrane / Q000201:enzymology; D003863:Depression / Q000097:blood / Q000378:metabolism / Q000628:therapy*; D004565:Electroconvulsive Therapy; D004789:Enzyme Activation; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism
D012964:Sodium; D000251:Adenosine Triphosphatases; D011188:Potassium; D002118:Calcium