[Potentialization of antibiotics by lytic enzymes].
Few lytic enzymes, specially papaine and lysozyme, acting on the membrane and cell wall structures facilitate effects of bacitracine, streptomycine and other antibiotics. Streptomycino resistant strains became sensibles to this antibiotic after contact with papaine and lysozyme. The results of tests in physiological suspensions concern only the lytic activity of enzymes. The results on nutrient medium concern together lytic, and antibiotic activities.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001433:Bacteriolysis; D004357:Drug Synergism; D005779:Immunodiffusion; D008826:Microbial Sensitivity Tests; D008837:Micrococcus / Q000187:drug effects; D009113:Muramidase / Q000494:pharmacology*; D010206:Papain / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects; D013291:Streptococcus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D009113:Muramidase; D010206:Papain
Potentialisation des antibiotiques par les enzymes lytiques