Paraproteinaemia in Sézary syndrome.
We have observed non-myelomatous monoclonal hypergammaglobulinaemia in a 61-year-old man with Sézary syndrome. Similar cases have not been reported before. Sézary cells of patients studied by other investigators were found to be helper T cells. The abundant production of T-lymphocytic stimuli may possibly explain in our case the occurrence of a paraprotein.
D001853:Bone Marrow / Q000276:immunology / Q000648:ultrastructure; D001854:Bone Marrow Cells; D002462:Cell Membrane / Q000276:immunology / Q000648:ultrastructure; D003873:Dermatitis, Exfoliative / Q000150:complications*; D005455:Fluorescent Antibody Technique; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007074:Immunoglobulin G; D007645:Keratoderma, Palmoplantar / Q000150:complications; D008206:Lymphatic Diseases / Q000150:complications*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D013577:Syndrome; D013601:T-Lymphocytes / Q000276:immunology / Q000648:ultrastructure
D007074:Immunoglobulin G