Kinetic properties of the primary inhibitor of plasmin from human plasma.
The interaction of human plasmin with the newly discovered alpha2-plasmin inhibitor was investigated. It was found from rate measurements that the reaction involves the rapid formation of a first enzyme-inhibitor complex, followed by the slow irreversible transition to another complex. L-Lysine influences the first step, but not the second.
D005341:Fibrinolysin / Q000037:antagonists & inhibitors*; D006801:Humans; D007700:Kinetics; D011485:Protein Binding
D005341:Fibrinolysin