title: [Study of the fibrinogen splitting products in the blood plasma in hyperfibrinolysis].
abstract: Dependence between the content of fibrinogen splitting products, rate of their formation and activation degree of the fibrinolytic system was studied in human and rabbit blood under conditions of hyperfibrinolysis in the experiments in vitro and in vivo. The effect of proteinases inhibitors on fibrinolysis and fibrinogen splitting products activation with streptokinase was also examined in the in vitro and in vivo experiments.
mesh_terms: D000818:Animals; D000933:Antifibrinolytic Agents / Q000494:pharmacology; D007611:Aprotinin / Q000494:pharmacology; D002021:Buffers; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005340:Fibrinogen / Q000378:metabolism*; D005341:Fibrinolysin / Q000378:metabolism; D005342:Fibrinolysis / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D010455:Peptides / Q000494:pharmacology; D011479:Protamines / Q000378:metabolism; D011480:Protease Inhibitors; D011817:Rabbits; D013300:Streptokinase / Q000494:pharmacology; D013997:Time Factors
chemical_list: D000933:Antifibrinolytic Agents; D002021:Buffers; D004791:Enzyme Inhibitors; D010455:Peptides; D011479:Protamines; D011480:Protease Inhibitors; D005340:Fibrinogen; D007611:Aprotinin; D013300:Streptokinase; D005341:Fibrinolysin
vernacular_title: Vyvchennia produktiv rozscheplennia fibrynochenu v plazmi krovi pry hiperfibrynolizi