Epoxide hydrase activity in mouse skin eidermis.
By fractionation of mouse epidermis a "microsomal" fraction may be obtained with a specific EH-activity at least 6-7 times higher than that of epidermis homogenates. Such enrichment allows to utilize the radioassay with 7--3H-styrene oxide as substrate which normally is too insensitive for organs with low levels of EH-activities. By the procedure developed the unambiguous demonstration of EH-activity in the epidermis of mouse skin is possible.
D000818:Animals; D002474:Cell-Free System; D004851:Epoxide Hydrolases / Q000378:metabolism*; D006836:Hydro-Lyases / Q000378:metabolism*; D008722:Methods; D051379:Mice / Q000378:metabolism*; D008861:Microsomes; D012867:Skin / Q000201:enzymology*; D014316:Tritium
D014316:Tritium; D004851:Epoxide Hydrolases; D006836:Hydro-Lyases