[The effect of a substance extracted from the urine of prepubertal children on circulating rat gonadotropins].
In the male rat, castration causes an increase of the LH level measured by radioimmunoassay. The application of a compound extracted from a impuber child urine and having anti-gonadotropic effects revealed biologically cannot stop this increase that is even put up by the treatment.
D000818:Animals; D002369:Castration; D002675:Child, Preschool; D005640:Follicle Stimulating Hormone / Q000097:blood; D006062:Gonadotropins / Q000037:antagonists & inhibitors; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D010455:Peptides / Q000652:urine*; D051381:Rats
D006062:Gonadotropins; D010455:Peptides; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Action d'une substance extraite de l'urine d'enfant impubère sur les gonadotrophines circulantes du rat