title: Damage caused by two finnish mushrooms, Cortinarius speciosissimus and Cortinarius gentilis on the rat kidney.
abstract: The toxicity of two mushroom species found in Finland, Cortinarius speciosissimus and Cortinarius gentilis, on the rat was studied. Dried, homogenized mushroom was given orally by stomach tubing. A dose of 500 mg dried mushroom/kg body weight, was used. It was demonstrated that both species caused renal damage. No damage could be shown in other organs. The renal histopathological changes corresponded to those of tubulo-interstitial nephritis. The sensitivity of different individuals to the fungal toxins varied greatly.
mesh_terms: D000818:Animals; D007668:Kidney / Q000473:pathology*; D008297:Male; D009145:Mushroom Poisoning / Q000150:complications / Q000473:pathology*; D009395:Nephritis, Interstitial / Q000139:chemically induced / Q000473:pathology; D051381:Rats