[Effect of parathyroid hormone and thyrocalcitonin on the cell membrane Na, K-ATP-ase of rat brain and kidney].
The influence of parathyroid hormone (PH) and thyrocalcitonine (TCT) on the enzymatic activity of ATP-ase systems of the membrane specimens of the cerebral cortex and renal cortex was investigated in experiments on rats. It was found that parathyroid hormone increased the activity of Na, K-ATP-ase and Ca-activated ATP-ase transport of the membranes in the brain and the kidneys both in vivo and in vitro. TCT caused analogous, but less expressed changes of the ATP-ase activity. Both hormones showed no influence on the Mg-ATP-ase activity of the both organs. It is supposed that the PH hormone influenced the membrane structures with the ATP-ase activity directly, while the action of TCT on them was mediated.
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D002116:Calcitonin / Q000494:pharmacology*; D002118:Calcium; D002462:Cell Membrane / Q000201:enzymology; D002540:Cerebral Cortex / Q000201:enzymology* / Q000648:ultrastructure; D004789:Enzyme Activation; D007672:Kidney Cortex / Q000201:enzymology* / Q000648:ultrastructure; D008274:Magnesium; D010281:Parathyroid Hormone / Q000494:pharmacology*; D011188:Potassium; D051381:Rats; D012964:Sodium; D013997:Time Factors
D010281:Parathyroid Hormone; D002116:Calcitonin; D012964:Sodium; D000251:Adenosine Triphosphatases; D008274:Magnesium; D011188:Potassium; D002118:Calcium
Vliianie paratireoidnogo gormona i tirokal'tsitonina na Na, K-ATF-szu kletochnykh membran golovnogo mozga i pochek krys