title: Study of adaptation on the regulation of proteosynthesis in the organism to changed nutritional conditions.
abstract: The authors studied the response of the regulation of proteosynthesis in the rat organism at the level of a model protein--haemoglobin--during developing protein depletion, comparing the response of rats encountering this situation for the first time with the response of animals specially prepared for it by a multiple depletion-repletion cycle. The changes in the response of both groups of animals to the same stimulus indicate that the data acquired in experience of these states are stored in the organism and form the basis of its changed response to a fresh load. The authors did not study the mechanism and site of storage of the information in question, or the mechanism of coordinated regulation, but they expressed the hypothesis that central regulation of protein biosynthesis could be involved.
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001772:Blood Cell Count; D004044:Dietary Proteins / Q000008:administration & dosage; D004906:Erythrocyte Count; D006454:Hemoglobins / Q000032:analysis; D008297:Male; D014176:Protein Biosynthesis; D011488:Protein Deficiency / Q000378:metabolism*; D051381:Rats; D012156:Reticulocytes; D013997:Time Factors
chemical_list: D004044:Dietary Proteins; D006454:Hemoglobins