[Pharmacokinetics and plasma albumen binding of iotroxic acid (Biliscopin), iodoxic acid (Endomirabil) and ioglycamine (Biligram) (author's transl)].
Pharmacokinetic data after injection of the new cholegraphic contrast medium iotroxic acid (Biliscopin) in man are reported and compared with the results of injections of ioglycamate and iodoxic acid. Iotroxic acid is less completely bound to plasma proteins than ioglycamate, but significancy more so than iodoxamate. Plasma protein binding depends on contrast concentration in the plasma, as does excretion in the urine. Biliary transport rate and maximal iodine concentration in the gall bladder are higher after injections of iotroxinate and iodoxamate than after ioglycamate.
D003287:Contrast Media / Q000378:metabolism*; D006207:Half-Life; D006801:Humans; D007463:Iodobenzoates / Q000378:metabolism*; D007471:Ioglycamic Acid / Q000378:metabolism; D007700:Kinetics; D011485:Protein Binding; D014283:Triiodobenzoic Acids / Q000031:analogs & derivatives / Q000378:metabolism*
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007471:Ioglycamic Acid
Pharmakokinetik und Plasmaeiweissbindung von Iotroxinsäure (Biliscopin), Iodoxamsäure (Endomirabil) und Ioglycaminsäure (Biligram)