[Monoamine oxidase type B and the function of Ca2+, Mg2+-dependent adenosine triphosphatase of preparations of sarcoplasmic reticulum vesicles].
Oxidative deamination by monoamine oxidases of B type in the preparations of sarcoplasmic reticulum vesicles from rabbit skeletal muscles of beta-phenylethylamine or benzylamine was accompanied by a decrease of both the active transport of Ca2+ into the vesicles and Ca2+, Mg2+-dependent ATP-ase activity. This decrease was prevented by pretreatment of the vesicles with deprenyl, a specific monoamine oxidase type B inhibitor. The aldehydes formed in the course of enzymatic deamination of the substrates of type B, monoamine oxidases, are considered as possible participants in the regulation of Ca2+, Mg2+-dependent ATP-ase activity.
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D001596:Benzylamines / Q000494:pharmacology; D001693:Biological Transport, Active; D002118:Calcium / Q000378:metabolism; D003864:Depression, Chemical; D004298:Dopamine / Q000494:pharmacology; D008274:Magnesium; D008995:Monoamine Oxidase / Q000378:metabolism*; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology; D010627:Phenethylamines / Q000494:pharmacology; D011817:Rabbits; D012519:Sarcoplasmic Reticulum / Q000201:enzymology*; D012701:Serotonin / Q000494:pharmacology
D001596:Benzylamines; D008996:Monoamine Oxidase Inhibitors; D010627:Phenethylamines; D012701:Serotonin; D008995:Monoamine Oxidase; D000251:Adenosine Triphosphatases; D008274:Magnesium; D002118:Calcium; D004298:Dopamine; D009638:Norepinephrine
Monoaminoksidaza tipa B i funktsii Ca2+, Mg2+-zavisimoĭ adenozintrifosfatazy preparatov vezikul sarkoplazmaticheskogo retikuluma