[Study of the distribution of haptoglobin groups in Marseilles, in normal and in cancer subjects].
Authors have studied 758 sera from normal subjects in Marseille area. The genotype frequencie Hp 1 is 0,39, similar that of France in general. The phenotype repartition is 16% for Hp 1-1, 45% for Hp 2-1 and 39% for Hp 2-2. People with carcinoma have shown a increase of the frequencie of the phenotype Hp 2-2 and a decrease of the frequencie of genotype Hp 1, mostly in lung carcinoma (Hp 1 = 0,29) and in carcinoma of digestive track (Hp 1 = 0,19). However, a control group, which is constituted by people hospitalized in the Anti-Cancerous Center, has a Hp 1 frequencie of 0,29 a well as lung carcinoma, no explication was found.
D005602:France; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D009369:Neoplasms / Q000235:genetics*; D010641:Phenotype
Etude de la répartition des groupes haptoglobines à Marseille, chez des sujets normaux et cancéreux