title: [Experimental investigations on the effectiveness of fenbendazole in parasitic helminths of the stomach, intestines and lung of cattle (author's transl)].
abstract: Helminth-free bulls were injected artificially with Ostertagia ostertagi (120 000 L3), Cooperia oncophora (240000 L3), Haemonchus spec. (1 000 L3) and/or Dictyocaulus viviparus (60 L3/kg) orally or intraruminally. The animals were treated with fenbendazole during the prepatent period or after having reached maturity. The effect of 5 mg fenbendazole/kg p.o. on 3-d, 10-d- and adult stages of Ostertagia ostertagi, Haemonchus spec. and Cooperia oncophora ranges between less than 94% and 100%. Particularly noticeable was the effect on 10-d-old Ostertagia ostertagi with less than 94%. 5 mg/kg fenbendazole orally removed nearly 100% of 6-d-, 13-d-, and adult stages of Dictyocaulus viviparus. Fenbendazole may be administered as a drench or as medicated feed. The safety of the compound permits the administration of excessively high doses without clinical signs.
mesh_terms: D000818:Animals; D001562:Benzimidazoles / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D004022:Dictyocaulus Infections / Q000188:drug therapy / Q000662:veterinary; D004064:Digestive System / Q000469:parasitology; D006188:Haemonchiasis / Q000188:drug therapy / Q000662:veterinary; D006374:Helminthiasis, Animal; D008168:Lung / Q000469:parasitology; D010029:Ostertagiasis / Q000188:drug therapy / Q000662:veterinary
chemical_list: D001562:Benzimidazoles
vernacular_title: Experimentelle Untersuchungen zur Wirksamkeit von Fenbendazol auf Magen-, Darm- und Lungerwurmbefall des Rindes