title: DNA and the cell cycle.
abstract: The cell cycle and its significance for pathology is reviewed. The molecular basis and questions of regulation in the cell cycle are discussed, along with deviations from the normal cycle in the form of polyploidy formation and aneuploidy in tumor cells. Automated prescreening processes may play a role in the future in daily routine diagnosis. Methods of cytophotometry with the possibility for objective pattern recognition will become significant in pathology in many ways, both in research and in routine work.
mesh_terms: D000782:Aneuploidy; D000818:Animals; D006332:Cardiomegaly; D002467:Cell Nucleus / Q000648:ultrastructure; D003581:Cytodiagnosis / Q000379:methods; D004247:DNA / Q000032:analysis / Q000096:biosynthesis; D004273:DNA, Neoplasm; D006131:Growth Inhibitors; D006801:Humans; D008938:Mitosis; D009369:Neoplasms / Q000175:diagnosis; D009698:Nucleoproteins / Q000096:biosynthesis; D010783:Photometry / Q000379:methods; D011123:Polyploidy
chemical_list: D004273:DNA, Neoplasm; D006131:Growth Inhibitors; D009698:Nucleoproteins; D004247:DNA