title: Two years oral use of chlorhexidine in man. I. General design and clinical effects.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001645:Biguanides / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003728:Dental Calculus / Q000517:prevention & control*; D003773:Dental Plaque / Q000517:prevention & control*; D004341:Drug Evaluation; D005260:Female; D005891:Gingivitis / Q000517:prevention & control*; D006801:Humans; D008297:Male; D013997:Time Factors; D014075:Tooth Discoloration / Q000139:chemically induced
chemical_list: D001645:Biguanides; D002710:Chlorhexidine