[Preventive action of pancuronium in cardiac rhythm disorders in children induced by administration of succinylcholine].
The author noted the development of tahycardia following the administration of succinylcholine, while repeated administration of the drug was followed by marked bradycardia in most of the children who received it. Administration of Pancuronium in amounts of 0,01 mg/kg of body weight, three minutes before the administration of succinylcholine resulted in the development of only very slight changes in the heart rhythm with a mean bradycardia of --0,7. Pancuronium was proved to provide prophylactic effects in rhythm disturbances occuring after intravenous reinjection of succinylcholine and this effect was superior to that obtained with d-tubocurarine.
D000293:Adolescent; D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000188:drug therapy / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D010197:Pancuronium / Q000627:therapeutic use*; D013390:Succinylcholine / Q000009:adverse effects*
D013390:Succinylcholine; D010197:Pancuronium
Acţiunea preventivă a pancuronium-ului în tulburările de ritm cardiac la copii date de administrarea de succinilcolină