[The effect of the argon laser on the vessels, the macro- and microcirculation of the mucosa of the hamster cheek-pouch. An intravitalmicroscopic study (author's transl)].
The mucosa of the cheek-pouch of five golden Syrian Hamsters was irradiated with the beam of an argonionlaser (diameter 0.5 mm and 200 mW). The effect on the micro- and macro-vessels and the bloodstream, especially of the microcirculation, is studied intravitalmicroscopically. In the microcirculation and also in the small and large venous and arterial vessels a restriction of bloodstream, praestasis, pendulumstream, stream reversal and some white microthrombi, -- emboli and agglutination of erythrocytes are visible. The bloodless welding of the vessels takes place even before the evaporation and coagulation necrosis of the surrounding epithelium of the mucosa as a result of the relatively selective effect of the Argon Laser on the reddish vessel-system by a continuous narrowing of the vessels-walls to the complete loss of their lumen rather than by a thrombosis. Firstly the capillaries, the venoles and the arterioles are obliterated, then those of middle size and at last the large venae and arteries in which case large vessels function for a moment as smaller ones. A continuously growing imbibition with increasing duration of the laser irradiation can be observed. Three clinically important phenomenon, depending on the laserdose can be observed: 1. a partial, 2. a subtotal and total obliteration of the network of the vessels, and 3. a total destruction of the blood-vessels and also of the tissue. Therefore clinically a subtotal or total network obliteration of the blood-vessels of strongly vascularised tissues, haemangiomas, teleangiectasias in case of morbus Rendu-Weber-Osler and livid enlarged nasal conchae might be obtained. Further a total tissue-destruction with a break in the continuity of the tissue for example with strongly vascularised carcinoma or its metastases might be effected.
D000818:Animals; D001128:Argon; D001158:Arteries / Q000503:physiopathology; D001777:Blood Coagulation; D002196:Capillaries / Q000503:physiopathology; D002610:Cheek / Q000601:surgery; D006224:Cricetinae; D006391:Hemangioma / Q000601:surgery; D006439:Hemodynamics; D053685:Laser Therapy; D007834:Lasers / Q000009:adverse effects*; D008833:Microcirculation; D009061:Mouth Mucosa / Q000098:blood supply*; D013684:Telangiectasis / Q000601:surgery; D014652:Vascular Diseases / Q000209:etiology* / Q000503:physiopathology; D014656:Vascular Surgical Procedures; D014680:Veins / Q000503:physiopathology
D001128:Argon
Wirkung des argonlasers auf die Gefässe, Mikro-und Makrozirkulation der Schleimhaut der Hamster-backentasche. Eine intravitalmikroskopische Studie