Lack of relationship of red cell enzyme activity to bilirubin and carboxyhemoglobin levels in healthy term infants.
A total of 32 term infants were studied in an attempt to confirm and extend the recent observation of Petrich & associates (14) that minor degrees of transient deficiences of the red cell enzymes glucose phosphate isomerase and glyceraldehyde-3-phosphate dehydrogenase were related to hyperbilirubinemia in otherwise healthy term infants. No relationships could be observed between the activity of these enzymes and the bilirubin level on day three. In addition, no correlation was present between bilirubin values and carboxyhemoglobin levels on day three, suggesting that in the healthy term infant excessive hemolysis is not usually responsible for the variations observed in bilirubin levels.
D001663:Bilirubin / Q000097:blood*; D002263:Carboxyhemoglobin / Q000378:metabolism*; D004163:Diphosphoglyceric Acids / Q000097:blood; D004912:Erythrocytes / Q000201:enzymology*; D005956:Glucose-6-Phosphate Isomerase / Q000097:blood; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases / Q000097:blood; D006454:Hemoglobins / Q000378:metabolism*; D006593:Hexokinase / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D010732:Phosphofructokinase-1 / Q000097:blood
D004163:Diphosphoglyceric Acids; D006454:Hemoglobins; D002263:Carboxyhemoglobin; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases; D006593:Hexokinase; D010732:Phosphofructokinase-1; D005956:Glucose-6-Phosphate Isomerase; D001663:Bilirubin