title: Laparoscopic ovarian biopsy in seventy-one amenorrhoeic patients.
abstract: During laparoscopy we performed 132 ovarian punch biopsies in seventy one amenorrhoeic patients. With increasing experience, laparoscopic ovarian biopsy is a valuable element in the examination of amenorrhoeic patients. Biopsy specimens with an edge length of 4-5 mm for surface and depth can be obtained during laparoscopy under general anaesthesia without any great risk or difficulty. When performed bilaterally, it provides a representative picture of the cellular structure and function of the ovaries and thus makes a contribution to the prognosis of a disturbance in the endocrine regulating-circuit of ovarian function. In addition, the ovarian biopsy provides information about the basic gonadotrophic situation of the patient as a longitudinal section. It should be included in the synopsis of all endocrine and genetic parameters of a patient, particularly in clinic in which the morphological substrate of disturbed functions and apparent diseases is still examined.
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D001706:Biopsy / Q000379:methods; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use; D006801:Humans; D010535:Laparoscopy; D006080:Ovarian Follicle / Q000473:pathology; D010053:Ovary / Q000473:pathology*
chemical_list: D005300:Fertility Agents, Female