The sedative effects of nicotinamide on gerbil wheel-running activity.
The activity of 5 groups of gerbils was monitored over 22 days. 3 of the groups received daily injections of nicotinamide (125, 250 or 500 mg/kg) and a 4th group received saline. The 5th group was untreated. The results indicated that both the 250 and 500 mg/kg nicotinamide administrations greatly reduced the activity levels of the gerbils.
D000818:Animals; D005849:Gerbillinae; D008297:Male; D009043:Motor Activity / Q000187:drug effects*; D009536:Niacinamide / Q000494:pharmacology*
D009536:Niacinamide