Clinical and hematological heterogeneity of T-cell derived lymphoproliferative diseases.
Human lymphoproliferative disorders characterized by T derived neoplastic cells include Sezary's syndrome and mycosis fungoides, most childhood lymphoblastic lymphomas, about a quarter of acute lymphoblastic leukemias and rare cases of poorly differentiated immunoblastic or lymphocytic lymphomas as well as a small percentage of chronic lymphocytic leukemias. Particular emphasis is placed on the immunological diagnosis of T derived cells using various membrane markers and on the hematological and clinical features of each of the disorders discussed.
D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology; D002648:Child; D003873:Dermatitis, Exfoliative / Q000276:immunology; D006801:Humans; D007945:Leukemia, Lymphoid / Q000276:immunology*; D008206:Lymphatic Diseases / Q000276:immunology*; D008228:Lymphoma, Non-Hodgkin / Q000276:immunology*; D009182:Mycosis Fungoides / Q000276:immunology*; D011537:Pruritus / Q000150:complications; D012397:Rosette Formation; D012878:Skin Neoplasms / Q000276:immunology*; D013577:Syndrome; D013601:T-Lymphocytes / Q000276:immunology