Influence of thymoxamine on changes in pupil diameter and accommodation produced by homatropine and ephedrine.
Local instillation of thymoxamine eye drops (0-1%) completely reversed the mydriasis produced by ephedrine (5%) but not that produced by ephedrine (5%) together with homatropine (0-5%). Small but significant changes in accomodation were found with ephedrine and with thymoxamine, as well as the larger expected changes with homatropine.
D000065:Accommodation, Ocular / Q000187:drug effects*; D000328:Adult; D002986:Clinical Trials as Topic; D004106:Dilatation; D004809:Ephedrine / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D013948:Moxisylyte / Q000494:pharmacology*; D009184:Mydriatics; D011680:Pupil / Q000187:drug effects*; D014326:Tropanes / Q000494:pharmacology*
D009184:Mydriatics; D014326:Tropanes; D004809:Ephedrine; D013948:Moxisylyte