title: [Clinical application of iodine 123 with special consideration of radionuclide purity, measuring accuracy and radiation dose(author's dose)].
abstract: Iodine 123 is a nearly "ideal" radionuclide for thyroid imaging.  The production of Iodine 123 requires cyclotrons or accelerators.  The production of multicurie amounts of Iodine 123 has been suggested through the use of high-energy accelerators (less than 60 MeV).  Most of the methods for the production of Iodine 123 using a compact cyclotron result in contamination with f.e. Iodine 124 which reduces the spatial resolution af imagining procedures and increases the radiation dose to the patient.  The radiation dose has been calculated for three methods of production.  The various contamination with Iodine 124, Iodine 125, and Iodine 126 result in comparable radiation dose of Iodine 131, provided that the time between production and application is more than four half-live-times of Iodine 123.
mesh_terms: D002648:Child; D006801:Humans; D007457:Iodine Radioisotopes; D009688:Nuclear Reactors; D011829:Radiation Dosage; D011835:Radiation Protection; D011851:Radioactivity; D011854:Radiochemistry; D011877:Radionuclide Imaging; D013959:Thyroid Diseases / Q000175:diagnosis; D013960:Thyroid Function Tests
chemical_list: D007457:Iodine Radioisotopes
vernacular_title: Klinische Anwendung von Jod-123 unter Berücksichtigung von Radionuklidreinheit, Messgenauigkeit und Strahlenbelastung