title: [Chloracne due to tetrachloro-2,3,7,8-dibenzo-p-dioxin in children (author's transl)].
abstract: Several cases of chloric acne have been observed in children after the accidental Seveso TCDD intoxication. The lesions consist in an inflammatory hyperkeratotic erythema of exposed areas, with numerous horny cysts, sometimes associated with granuloma annulare aspects of the hands. All lesions have the same histological pattern and atrophoderma vermiculata is often their ultimate evolution. These cases are similar to the epidemic follicular keratosis observed in 1946 around Bâle in Switzerland; thus the clinical and genetic evolution of these patients may be foreseen.
mesh_terms: D000152:Acne Vulgaris / Q000139:chemically induced* / Q000473:pathology; D002675:Child, Preschool; D004147:Dioxins / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D000072317:Polychlorinated Dibenzodioxins / Q000009:adverse effects*; D012867:Skin / Q000473:pathology
chemical_list: D004147:Dioxins; D000072317:Polychlorinated Dibenzodioxins
vernacular_title: Chloracné au tétrachloro-2,3,7,8-dibenzo-p-dioxine chez les enfants.