Variations in melanin and riboflavin content of amphibian liver under the influence of reserpine and amphetamine.
By means of paper chromatography, Lactobacillus casei test and the staining method with the Feulgen reaction, the effects of reserpine and amphetamine on riboflavin and melanin were studied in the liver of Triturus cristatus. It was demonstrated that the concentrations of both melanin and riboflavin can be altered by the influence of these drugs. From the results obtained it is suggested that riboflavin shows a correlation with the density of melanin.
D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D008099:Liver / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D008543:Melanins / Q000378:metabolism*; D008544:Melanocytes / Q000187:drug effects; D011621:Pteridines / Q000378:metabolism; D012110:Reserpine / Q000494:pharmacology*; D012256:Riboflavin / Q000378:metabolism*; D013997:Time Factors; D014319:Triturus
D008543:Melanins; D011621:Pteridines; D012110:Reserpine; D000661:Amphetamine; D012256:Riboflavin