Differences and similarities in chromatin structure of Neurospora crassa and higher eucaryotes.
The subunit structure of Neurospora chromatin which contains a full histone complement (Goff, 1976) exhibits both differences and similarities to chromatin of higher eucaryotes. The size of the DNA per subunit is only 170 +/- 5 base pairs, as compared to 200 base pairs in higher eucaryotes. However, the internal structures of the subunits are closely related. They contain 140 base pairs of DNA that are more tightly associated with the histone core and similarly arranged on the outside of the subunit. Hence the difference in structure resides in a shorter linker region of adjacent subunits in Neurospora chromatin. This is supported by a reduced primary cutting site and a lower content of lysines in histone H1. The role of H1 and its relation to the linker region are discussed.
D000818:Animals; D002843:Chromatin / Q000032:analysis*; D004247:DNA / Q000032:analysis*; D003851:Deoxyribonucleases; D008099:Liver / Q000032:analysis; D009491:Neurospora / Q000032:analysis*; D009492:Neurospora crassa / Q000032:analysis*; D009690:Nucleic Acid Conformation; D011487:Protein Conformation; D051381:Rats; D013045:Species Specificity
D002843:Chromatin; D004247:DNA; D003851:Deoxyribonucleases