Skin exfoliation and purulent conjunctivitis in a new mutant-the exfoliative mouse.
A spontaneous autosomal recessive mutation has been named the exfoliative mouse (genotype ex/ex). Exfoliative mice suffer a transient purulent conjunctivitis in their 3rd week and an exfoliative skin disease in their 4th week. Gram-negative bacilli are present in blood and cerebrospinal fluid during the conjunctivitis stage, and in skin during the exfoliative period. The mutant can be differentiated from the ichthyotic mouse mutant.
D000818:Animals; D003231:Conjunctivitis / Q000235:genetics / Q000473:pathology*; D003873:Dermatitis, Exfoliative / Q000235:genetics / Q000473:pathology*; D004195:Disease Models, Animal; D051379:Mice; D008815:Mice, Inbred Strains; D009154:Mutation; D012867:Skin / Q000473:pathology