[Enzyme and protein release from human granulocytes: effect of ATP].
The authors study the proteins and enzymes release of resting and phagocytosing human leukocytes suspended in Krebs-Ringer-Phosphate milieu containing or not glucose. They measure the metabolic level and the percentage of enzymes release and show the influence of ATP on this phenomenon. These results are in favour of a direct action of ATP on the cellular membrane.
D000255:Adenosine Triphosphate / Q000378:metabolism / Q000494:pharmacology*; D000328:Adult; D002462:Cell Membrane / Q000187:drug effects; D002463:Cell Membrane Permeability / Q000187:drug effects; D005947:Glucose / Q000378:metabolism; D005966:Glucuronidase / Q000378:metabolism; D006098:Granulocytes / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D066298:In Vitro Techniques; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D007773:Lactates / Q000378:metabolism; D007962:Leukocytes / Q000502:physiology*; D010587:Phagocytosis; D011773:Pyruvates / Q000378:metabolism
D007773:Lactates; D011773:Pyruvates; D000255:Adenosine Triphosphate; D007770:L-Lactate Dehydrogenase; D005966:Glucuronidase; D005947:Glucose
Sortie d'enzymes et protéines à partir de granulocytes humains : influence de l'ATP