Diagnosis of experimentally induced bronchogenic tumours in the european hamster with bronchographs.
Four groups of European hamsters were treated subcutaneously once weekly for life with 1/20 or 1/40 the diethylnitrosamine LD 50. Three animals from each treatment group and the two control groups were examined every three weeks by means of bronchographic technique. In four of the animals the bronchograms showed early neoplastic alterations of the bronchial system. The results demonstrate that bronchography is a suitable method for the diagnosis of bronchogenic tumours in the European hamster and that it also allows for the detection of displacing neoplasms of non-bronchogenic origin in the region of the tracheal bifurcation.
D000818:Animals; D001995:Bronchography; D002283:Carcinoma, Bronchogenic / Q000139:chemically induced / Q000000981:diagnostic imaging*; D006224:Cricetinae; D005260:Female; D008175:Lung Neoplasms / Q000139:chemically induced / Q000000981:diagnostic imaging*; D008297:Male; D009374:Neoplasms, Experimental; D009602:Nitrosamines / Q000494:pharmacology
D009602:Nitrosamines