Sex chromatin and cytogenetic survey of 10417 adult males and 357 children institutionalized in Belgian institutions for mentally retarded patients.
A survey of adult male immates of the major institutions for mental patients in Belgium was undertaken in 1965. Out of 10417 males examined 61 had positive sex chromatin (5.8%); 201 had bilateral small testis (1.9%), 4 hypogonad patients carried a D/D translocation. Out of 857 karyotyped children, 2.9% carried an autosomal or sex-chromosomal anomaly other than trisomy G. This prevalence of chromosomal anomalies in children with low I.Q. (less than 50) emphasizes the need for further studies.
D000293:Adolescent; D000328:Adult; D001530:Belgium; D002648:Child; D002674:Child, Institutionalized; D002869:Chromosome Aberrations / Q000453:epidemiology*; D025063:Chromosome Disorders; D002901:Chromosomes, Human, 13-15; D004314:Down Syndrome / Q000453:epidemiology; D006801:Humans; D007006:Hypogonadism / Q000453:epidemiology; D008607:Intellectual Disability / Q000235:genetics*; D008297:Male; D012728:Sex Chromatin / Q000032:analysis*; D012729:Sex Chromosome Aberrations / Q000453:epidemiology; D014178:Translocation, Genetic