title: Surgical treatment of aneurysm of the ascending aorta with aortic insufficiency and marked displacement of the coronary ostia.
abstract: Six patients with a large aneurysm of the ascending aorta involving the root of the aorta and severe aortic valve insufficiency owing to marked annular dilatation were treated by replacement of the ascending aorta and aortic valve with a composite unit. It was also necessary to transpose the origin of the coronary arteries with the use of saphenous vein grafts. In 3 patients, the aneurysm was due to a chronic dissection. In one patient, the aneurysm extended beyond the arch of the aorta. There were no operative deaths. One patient died suddenly of pulmonary emboli 11 months after surgery. The remaining 5 patients are doing well, 5 months to 4 years postoperatively.
mesh_terms: D000328:Adult; D001014:Aortic Aneurysm / Q000150:complications / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000209:etiology* / Q000601:surgery; D001807:Blood Vessel Prosthesis / Q000379:methods*; D003331:Coronary Vessels / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene; D014182:Transplantation, Autologous; D014680:Veins / Q000637:transplantation
chemical_list: D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene