The effect of different kinds of animal housing on parameters of collagen metabolism in guinea pigs.
Parameters of collagen metabolism were investigated in guinea pigs, both untreated and treated with glucocorticoids. One series consisted of animals housed under normal conditions, the others of SPF animals from the same strain. There are marked differences in certain parameters, including the hydroxyproline content and the reaction of the collagen to glucocorticoids.
D000818:Animals; D001842:Bone and Bones / Q000378:metabolism; D003094:Collagen / Q000378:metabolism*; D004777:Environment; D005938:Glucocorticoids / Q000494:pharmacology*; D006168:Guinea Pigs; D006909:Hydroxyproline / Q000378:metabolism; D008297:Male; D012867:Skin / Q000378:metabolism; D013047:Specific Pathogen-Free Organisms
D005938:Glucocorticoids; D003094:Collagen; D006909:Hydroxyproline