title: Total anomalous pulmonary venous return. Review of 125 patients treated surgically.
abstract: One hundred twenty-five patients undergoing surgical correction of total anomalous pulmonary venous return were studied. The overall mortality was 37% and was related to age at the time operation was required. Mortality was 57% during the first year of life, 29% in patients between 13 and 24 months, and 15% in those between 2 and 10 years; no deaths occurred in those over 10 years. Mortality was highest in patients with infracardiac lesions (62%), and lowest in those with cardiac defects (30%). The major cause of death was pulmonary edema, and survival was closely related to the degree of increased pulmonary vascular resistance. Surgical treatment should be delayed until at least 6 months of age, but the development of congestive heart failure may necessitate earlier operation.
mesh_terms: D000293:Adolescent; D000328:Adult; D001807:Blood Vessel Prosthesis; D002648:Child; D002675:Child, Preschool; D004209:Disposable Equipment; D005112:Extracorporeal Circulation / Q000379:methods; D005260:Female; D006325:Heart Atria / Q000601:surgery; D006330:Heart Defects, Congenital / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D006346:Heart Septum / Q000601:surgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008026:Ligation; D008297:Male; D008722:Methods; D008875:Middle Aged; D010106:Oxygenators; D011093:Polyethylene Terephthalates; D011183:Postoperative Complications / Q000401:mortality; D011379:Prognosis; D011652:Pulmonary Circulation; D011667:Pulmonary Veins / Q000002:abnormalities* / Q000601:surgery; D014655:Vascular Resistance
chemical_list: D011093:Polyethylene Terephthalates