title: Radiochromatography of 5-3H-uridine derivatives found in trichloracetic and soluble fractions of mouse brain, liver, muscle and blood.
abstract: Trichloracetic acid soluble fractions from the mouse brain, liver, muscle and blood were chromatographed in three solvent systems after a subcutaneous injection of 5-3H-uridine (boric acid -- ethanol -- water -- ammonium hydroxide; n-butanol -- acetic acid -- water; IM ammonium acetate -- 95% ethanol). The amount of uridine converted to uracil in the brain and blood highly prevailed over that phosphorylated to UMP. On the contrary, the amount of 3H-;uracil was small in the LIVER AND MUSCLe, the majority of 3H-uridine being converted to UMP.
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D051379:Mice; D009132:Muscles / Q000378:metabolism*; D012313:RNA / Q000096:biosynthesis; D012995:Solubility; D014238:Trichloroacetic Acid; D014316:Tritium; D014529:Uridine / Q000031:analogs & derivatives / Q000097:blood / Q000378:metabolism*
chemical_list: D014316:Tritium; D014238:Trichloroacetic Acid; D012313:RNA; D014529:Uridine