A case of small-cell Sézary's syndrome with null-cell features.
A case of the small-cell variant of Sézary's syndrome (SS) is reported in which the SS cells lacked the surface-marker characteristics of both T- and B-cells. In particular, the SS cells failed to form E-rosettes even with a sensitive technique using 2-amino-ethylisothiouronium bromide (AET)-treated sheep red blood cells. The significance of these findings is briefly considered in relation to the existing literature.
D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology; D003873:Dermatitis, Exfoliative / Q000276:immunology*; D006801:Humans; D007104:Immune Adherence Reaction; D008206:Lymphatic Diseases / Q000276:immunology*; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D012878:Skin Neoplasms / Q000276:immunology*; D013577:Syndrome; D013601:T-Lymphocytes / Q000276:immunology; D000338:beta-Aminoethyl Isothiourea
D000338:beta-Aminoethyl Isothiourea