Effects of macromolecular compounds on human leukocyte beta-galactosidase activity.
The enzyme properties of leukocyte beta-galactosidase and the effects of macromolecular compounds on its activity were studied in detail. It was demonstrated that various macromolecular compounds markedly influence the activity of beta-galactosidase. These phenomena should be taken into account when considering the biochemical abnormalities of tissues of patients with mucopolysaccharidoses and mucolipidoses.
D002850:Chromatography, Gel; D003208:Concanavalin A / Q000494:pharmacology; D003956:Dialysis; D005696:Galactosidases / Q000097:blood*; D006025:Glycosaminoglycans / Q000494:pharmacology; D006801:Humans; D007525:Isoelectric Focusing; D007700:Kinetics; D007962:Leukocytes / Q000201:enzymology*; D001616:beta-Galactosidase / Q000037:antagonists & inhibitors / Q000097:blood*
D006025:Glycosaminoglycans; D003208:Concanavalin A; D005696:Galactosidases; D001616:beta-Galactosidase