title: Deletions of ribosomal protein genes in Escherichia coli merodiploids heterozygous for resistance to streptomycin and spectinomycin.
abstract: In a merodiploid strain of Escherichia coli heterozygous for the ribosomal protein genes spc and str, deletions were observed preventing the expression of either gene but permitting the expression of the other. This suggests that the spc and str genes are in separate transcriptional units.
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis; D002869:Chromosome Aberrations; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D004171:Diploidy; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects*; D005796:Genes; D006579:Heterozygote; D009154:Mutation; D012269:Ribosomal Proteins / Q000096:biosynthesis*; D000198:Spectinomycin / Q000494:pharmacology; D013307:Streptomycin / Q000494:pharmacology; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D012269:Ribosomal Proteins; D000198:Spectinomycin; D013307:Streptomycin