title: [Plasma concentration and metabolic clearance rate of aldosterone at weaning, at puberty, and in adult guinea pigs].
abstract: Plasma aldosterone concentrations were measured by radioimmunoassay and metabolic clearance rates (M.C.R.) were determined by a continuous infusion of H3-aldosterone on day 20 and 50 and at 3, 6 and 24 months in the male and the female guinea-pig. Plasma aldosterone concentration rose gradually from day 20 up to 24 months. At every stage the values were always higher in the female than in the male. M.C.R. (1/24 h/100 g) decreased from day 20 to 24 months and appeared to be sex-dependent in the guinea-pig.
mesh_terms: D000367:Age Factors; D000450:Aldosterone / Q000097:blood / Q000378:metabolism*; D000818:Animals; D000831:Animals, Newborn; D005260:Female; D006168:Guinea Pigs; D006400:Hematocrit; D008297:Male; D008657:Metabolic Clearance Rate; D011188:Potassium / Q000097:blood; D012737:Sex Factors; D012741:Sexual Maturation; D012964:Sodium / Q000097:blood
chemical_list: D000450:Aldosterone; D012964:Sodium; D011188:Potassium
vernacular_title: Concentration plasmatique et taux de clairance métabolique de l'aldostérone chez le cobaye au sevrage, à la puberté et à l'âge adulte.