Intracisternal virus-like particles in a human pituitary adenoma.
Electron microscopy revealed the presence of intracisternal virus-like particles in a mixed pituitary adenoma consisting of growth hormone cells and prolactin cells. The tumor was removed by surgery from a 48 year old man with a multiple endocrine adenomatosis type I syndrome. The significance of virus-like particles in the pathogenesis of pituitary adenomas remains to be elucidated.
D000236:Adenoma / Q000382:microbiology*; D004721:Endoplasmic Reticulum / Q000382:microbiology* / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000382:microbiology*