[The effect of plasmin on kallikreinogen].
The effect of purified plasmin preparation on kallikreinogen isolated from rat blood plasma was studied by chromatography on DEAE-Sephadex. Plasmin was shown to affect kallikreinogen to form an active enzyme--kallikrein. The dependence of the activation degree on the plasmin activity and incubation time was studied. Evidence was found for the absence of Hagemann factor in the reaction medium, which excludes the possibility of indirect action of plasmin on kallikreinogen through the Hagemann factor fragments formed.
D000818:Animals; D004789:Enzyme Activation; D004792:Enzyme Precursors; D005341:Fibrinolysin; D007610:Kallikreins; D051381:Rats
D004792:Enzyme Precursors; D007610:Kallikreins; D005341:Fibrinolysin
Deĭstvie plazmina na kallikreinogen