[Suppressor cells in the "in vitro" induced cell mediated immune response: their origin and target (author's transl)].
Suppressor cells, produced in a mixed lymphocyte reaction between CBA and irradiated DBA/2 lymphocytes, inhibited the production of cytotoxic CBA cells in a second MLR. There were several suppressor cells: T and non-T cells, cells with or without Fc-receptors, and cytotoxic as well as non-cytotoxic cells. Reconstitution of the in vitro production of cytotoxic as well as non-cytotoxic cells. Reconstitution of the in vitro production of cytotoxic lymphocytes in suppressed cultures by supplementary CBA cells was better than that which took place after the addition of DBA/2 stimulator cells.
D000818:Animals; D001666:Binding Sites, Antibody; D003601:Cytotoxicity Tests, Immunologic; D007111:Immunity, Cellular; D007141:Immunoglobulin Fc Fragments; D007165:Immunosuppression Therapy; D007959:Lymphocyte Culture Test, Mixed; D051379:Mice; D008808:Mice, Inbred CBA; D008811:Mice, Inbred DBA
D007141:Immunoglobulin Fc Fragments
Cellules suppressives dans la réponse a médiation cellulaire induite in vitro: leurs origines et leurs cibles.