title: [Vitamins K and E and the functional state of connective tissue].
abstract: The function of the connective tissue in the skin of albino rats with the vitamin K deficiency was studied. Changes both in the cellular elements and in the fibrous structures (deranged differentiation of cellular elements, changes in the collagenformation, accumulation of acid mucopolysaccarides, etc.) were revealed. All of the mentioned changes are eliminated not only by introduction of vicasol, but also by that of alpha-tocopherol.
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D003238:Connective Tissue / Q000378:metabolism / Q000503:physiopathology*; D004247:DNA / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism; D007501:Iron / Q000378:metabolism; D008297:Male; D011134:Polysaccharides / Q000378:metabolism; D051381:Rats; D012867:Skin / Q000503:physiopathology; D014810:Vitamin E / Q000627:therapeutic use*; D014812:Vitamin K / Q000627:therapeutic use; D014813:Vitamin K Deficiency / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology*
chemical_list: D006025:Glycosaminoglycans; D011134:Polysaccharides; D014812:Vitamin K; D014810:Vitamin E; D004247:DNA; D007501:Iron
vernacular_title: Vitaminy K i E i funktsional'noe sostoianie soedinitel'noĭ tkani