The role of increased Ca++ influx as a possible additional adaptive mechanism in experimental left ventricular hypertrophy (exp LVH).
Membrane potentials, isometric contraction and autohistoradiography with 45Ca in papillary muscle of rats with experimental LVH without cardiac failure as compared with sham-operated animals proved an increased Ca influx per beat and a Ca accumulation at or near the sarcolemma. This phenomenon is regarded as an additional mechanism for the improvement of the cardiac performance in the compensatory stage of the experimental LVH without cardiac failure.
D000200:Action Potentials; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D006332:Cardiomegaly / Q000378:metabolism* / Q000503:physiopathology; D007473:Ion Channels; D008564:Membrane Potentials; D051381:Rats; D012508:Sarcolemma / Q000378:metabolism
D007473:Ion Channels; D002118:Calcium