[Effect of amizil and arecoline on the activity of Na, K-ATP-ase and concentration of Na+ and K+ ions in rat brain].
A study was made of the activity of Na, K-ATP-ase and the Na+ and K+ content in the brain of rats with the action of arecoline and amizyl. Both arecoline and amizyl increased the Na, K-ATP-ase activity. This could be associated with the changes in the redistribution of the Na+ and K+ ions in the nerve cell. Arecoline proved to cause changes in the electrolyte distribution by the depolarization type, whereas amizyl--by the type of hyperpolarization of the nerve cell membrane.
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D001115:Arecoline / Q000494:pharmacology*; D001535:Benactyzine / Q000494:pharmacology*; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D011188:Potassium / Q000032:analysis*; D051381:Rats; D012964:Sodium / Q000032:analysis*; D013997:Time Factors
D001115:Arecoline; D001535:Benactyzine; D012964:Sodium; D000251:Adenosine Triphosphatases; D011188:Potassium
Vliianis amizila i arekolina na aktivnost' Na, K-ATF-azy i soderzhanie ionov Na+ i K+ V GOLOVNOM MOZGE KRYS