[Repeated Keratoplasties and graft rejection].
It is always difficult to estimate the risk of recurrence of maladie due greffon in repeat grafts, and the intricate factors in these cases are open to complex analysis. A number of grafts have been divided into those which were repeated on the same eye and those on the two eyes of the same subject. In the majority of cases the grafts were penetrating (105 out of 118 cases), and the overall analysis of the results is dependent on the following factors: -- Grafts performed as primary procedures in one eye or both eyes: if they develop maladie due greffon, it is usually the 'endothelial' form which appears between the first and third month; the prognosis is good (53-66 p. 100 cure with steroid therapy). It was noticed that when grafts were performed on both eyes, there was a risk of developing maladie due greffon on the eye with the first graft simultaneously if it developed in the second eye. -- Repeated grafts on the same eye caused maladie due greffon of varying types (endothelial, stromal and mixed) with a much earlier occurrence. The prognosis is worse (6 p. 100 cure, 33 p. 100 semi-failure and 60 p. 100 failure). -- Finally repeated grafts on severe leucomas (burns, leucoma adherens, inflammatory keratopathies with active neovascularisation, etc.): these practically all end in failure due either to immunological reactions or inflammatory or cicatrical changes. A table of visual acuities obtained after treatment in cases of cure, incomplete cure and failure is given at the end of this paper.
D003316:Corneal Diseases / Q000601:surgery*; D016039:Corneal Transplantation; D005126:Eye Burns / Q000601:surgery; D006084:Graft Rejection; D006801:Humans; D008722:Methods; D014184:Transplantation, Homologous
Kératoplasties successives et maladie du greffon