title: [Chromosomal structures of Pseudomonas testosteroni. IV. Effect of testosterone on RNA-synthesis (author's transl)].
abstract: Testosterone degrading enzymes are synthesized de novo by bacterium P. testosteroni to utilize testosterone-like steroids as the only source of carbon. RNA-synthesis of the whole lysate of testosterone-induced bacteria was found to be 15% reduced compared to the control, suggesting a cytoplasmatic factor which modulates chromatin associated RNA-polymerase activity.
mesh_terms: D002876:Chromosomes, Bacterial / Q000378:metabolism*; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D007700:Kinetics; D011549:Pseudomonas / Q000187:drug effects / Q000378:metabolism*; D012329:RNA, Bacterial / Q000096:biosynthesis*; D013739:Testosterone / Q000494:pharmacology*; D014158:Transcription, Genetic / Q000187:drug effects
chemical_list: D012329:RNA, Bacterial; D013739:Testosterone; D012321:DNA-Directed RNA Polymerases
vernacular_title: Chromosomale strukture von Pseudomona testosteroni. IV. Wirkung von Testosteron auf die RNA-Synthese.