title: Tissue specific distribution of sulfated mucopolysaccharides in mammals.
abstract: A comparative study on the distribution of sulfated mucopolysaccharides in several tissues of five mammalian species is reported. It is shown that each tissue has a characteristic composition differing from each other regarding the relative amount, type and molecular size of chondroitin sulfate A/C, chondroitin sulfate B and heparan sulfate. It is also shown that the same tissue from different mammals has the same types and proportions of sulfated mucopolysaccharides, but with different molecular weights. Exception to this rule was observed for the distribution of heparin which was present only in a few tissues of the five mammals studied. The possible involvement of the sulfated mucopolysaccharides in cell recognition and/or adhesiveness is discussed in view of this characteristic distribution.
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D002417:Cattle; D002809:Chondroitin Sulfates / Q000032:analysis; D003871:Dermatan Sulfate / Q000032:analysis; D004285:Dogs; D006025:Glycosaminoglycans / Q000032:analysis*; D006168:Guinea Pigs; D006497:Heparan Sulfate / Q000032:analysis; D006801:Humans; D007082:Ileum / Q000032:analysis; D007668:Kidney / Q000032:analysis; D008970:Molecular Weight; D009132:Muscles / Q000032:analysis; D009928:Organ Specificity; D011817:Rabbits; D013045:Species Specificity; D013552:Swine
chemical_list: D002809:Chondroitin Sulfates; D003871:Dermatan Sulfate; D006025:Glycosaminoglycans; D006497:Heparan Sulfate