[Toxic staphylococcal cutaneous necrolysis (scalded skin syndrome) (author's transl)].
The exfoliating exotoxin of serotype II staphylococci is responsable of three diseases with prevailing dermatologic symptoms: staphylococcal scarlet fever, staphylococcal Lyell syndrom and Ritter-Lyell disease. Melish demonstrated the effect of staphylococcal exotoxin on new-born mice less than five days old. This experimental model allowed to study the characteristics of the toxin. Precocious antistaphylococcal antibiotherapy is necessary.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003873:Dermatitis, Exfoliative / Q000209:etiology* / Q000266:history / Q000473:pathology; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D009336:Necrosis / Q000209:etiology; D012541:Scarlet Fever / Q000209:etiology* / Q000473:pathology; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D013211:Staphylococcus aureus / Q000145:classification / Q000378:metabolism; D013262:Stevens-Johnson Syndrome / Q000209:etiology* / Q000266:history / Q000473:pathology; D014118:Toxins, Biological / Q000302:isolation & purification / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D014118:Toxins, Biological
Le syndrome toxique staphylococcique cutané dit des enfants ébouillantés (scalded skin syndrome).