title: [Course of pregnancy and labor after prenatal diagnosis of genetic defects and abnormalities].
abstract: 138 patients were referred to us to prenatal diagnosis of genetic defects. Only in 120 patients the diagnostic procedures could also be carried out. In 75% the amniocentesis was performed to establish the amnion cell culture and in 22.5% for analysis of alphafetoprotein and for performance of fetography. In 4.2% a genetic indication for interruption was found by the prenatal diagnosis. Among the 61 terminated pregnancies a premature delivery occurred in 13.1%. The operating frequency of delivery was 16.2% and the perinatal mortality was 1.6%.
mesh_terms: D000649:Amniocentesis / Q000379:methods*; D000013:Congenital Abnormalities / Q000175:diagnosis*; D004314:Down Syndrome / Q000175:diagnosis; D005260:Female; D005313:Fetal Death / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D007744:Obstetric Labor Complications / Q000235:genetics*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000235:genetics*
vernacular_title: Schwangerschaftsverlauf und Geburt nach pränataler Diagnostik genetischer Defekte und Missbildungen.