Human lymphoid cells release a lymphocyte-attaching and stimulating product.
In 4-h cultures human lymphoid cells release into culture supernatants substances capable of stimulating the proliferation of lymphocytes different at HLA system from cells which released the stimulating substances. Culture supernatant components responsible for stimulation are attached to lymphocytes allogeneic to their producers and on incubation with them can be removed from culture supernatants.
D000818:Animals; D002462:Cell Membrane / Q000276:immunology; D006680:HLA Antigens / Q000302:isolation & purification; D006801:Humans; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed / Q000379:methods; D008214:Lymphocytes / Q000276:immunology* / Q000378:metabolism; D051379:Mice; D013601:T-Lymphocytes / Q000276:immunology; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D006680:HLA Antigens; D014316:Tritium; D013936:Thymidine