[The pharmaco-kinetics of angiographic contrast media, with special reference to the extra-vascular space. An experimental study on dogs. Paper II. Pharmaco-kinetics of an angiographic contrast medium used for selective angiography (author's transl)].
Basic studies were carried out on experimental animals in order to investigate the pharmaco-kinetics of angiographic contrast media when used in various ways. Injections were carried out through angiographic catheters in a "physiological angiographic" manner. Measurements obtained by using radioactive compounds have shown that the distribution and excretion of the contrast medium are independent of the site of injection. The kinetics of the contrast within an organ do not differ, whether it is injected selectively or not. The results of all the experiments will be discussed at the conclusion of the third paper.
D000792:Angiography; D000818:Animals; D001011:Aorta / Q000033:anatomy & histology; D001012:Aorta, Abdominal; D001916:Brachial Artery; D002404:Catheterization / Q000295:instrumentation; D002445:Celiac Artery; D003287:Contrast Media / Q000008:administration & dosage / Q000378:metabolism*; D003974:Diatrizoate Meglumine / Q000378:metabolism; D004285:Dogs; D007269:Injections, Intra-Arterial; D014316:Tritium
D003287:Contrast Media; D014316:Tritium; D003974:Diatrizoate Meglumine
Pharmakokinetik angiographischer Kontrastmittel unter besonderer Berücksichtigung des extravasalen Raumes. Eine experimentelle Grundlagenstudie an Hunden zur Charakterisierung der Angiographica. II. Mitteilung: Pharmakokinetik eines angiographischen Kontrastmittels unter den Bedingungen einer selektiven -- "angiographischen" -- Applikation