[In vitro studies to elucidate the fibrinolytic activity in cerebrospinal fluid altered by inflammation and hemorrhage and having pathologic protein values].
Using selectively immunological methods, it was possible, through FSP determination, for plasmin activities and plasminogen concentrations to be occasionally and exclusively detected in inflammatorily altered liquores and in bloody liquores, respectively. Thus, bloody cerebrospinal fluid, in contrast with inflammatorily altered liquor, usually shows free fibrinolytic activity, so that antifibrinolytic therapy of intracranial aneurysmal hemorrhage is pathophysiologically justifiable.
D002493:Central Nervous System Diseases / Q000134:cerebrospinal fluid*; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis*; D002908:Chronic Disease; D005337:Fibrin / Q000134:cerebrospinal fluid*; D005338:Fibrin Fibrinogen Degradation Products / Q000134:cerebrospinal fluid; D005340:Fibrinogen / Q000134:cerebrospinal fluid*; D005341:Fibrinolysin / Q000134:cerebrospinal fluid*; D006470:Hemorrhage; D006801:Humans; D007249:Inflammation; D010958:Plasminogen / Q000134:cerebrospinal fluid*
D002556:Cerebrospinal Fluid Proteins; D005338:Fibrin Fibrinogen Degradation Products; D005337:Fibrin; D005340:Fibrinogen; D010958:Plasminogen; D005341:Fibrinolysin
In-vitro Versuche zur Klärung der fibrinolytischen Aktivität in entzündlich veränderten und blutigen Liquores mit pathologischen Proteinwerten.