title: The hydration of proteoglycans of bovine cornea.
abstract: The water sorptive and retentive capacities of three corneal proteoglycans with different keratan sulfate/chondroitin-4-sulfate compositions were investigated. The calcium salt of a predominantly keratan sulfate containing proteoglycan had hydration properties similar to that of calcium keratan sulfate. The proteoglycan containing predominantly calcium chondroitin-4-sulfate side chains sorbed water to a greater extent than pure calcium chondroitin-4-sulfate but its retentive power was somewhat less. The proteoglycan containing about twice as much keratan sulfate as chondroitin-4-sulfate, on a dissaccharidic molar basis and had hydration properties which were closer to the behavior of chondroitin-4-sulfate than keratan sulfate. The results are discussed in terms of structure and polymer interaction in the proteoglycan matrices.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002118:Calcium; D002241:Carbohydrates / Q000032:analysis; D002417:Cattle; D002807:Chondroitin / Q000032:analysis; D002852:Chromatography, Ion Exchange; D003315:Cornea / Q000032:analysis*; D006025:Glycosaminoglycans; D007633:Keratins / Q000032:analysis; D011485:Protein Binding; D011509:Proteoglycans / Q000032:analysis; D014867:Water
chemical_list: D000596:Amino Acids; D002241:Carbohydrates; D006025:Glycosaminoglycans; D011509:Proteoglycans; D014867:Water; D007633:Keratins; D002807:Chondroitin; D002118:Calcium