[Spontaneous leukemia of AKR mice. Successful passive immunization with goat antibodies against isolated glycoprotein gp71 of Friend leukemia virus].
The occurrence of fatal spontaneous leukemia in AKR mice could be drastically reduced by passive immunization with goat antibody against isolated murine Friend virus glycoprotein gp71, possessing high group specific reactivity. The success depended on the time of antibody application. The best results were achieved when mothers and babies were inoculated.
D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000008:administration & dosage*; D005622:Friend murine leukemia virus / Q000276:immunology; D006041:Goats / Q000276:immunology; D007112:Immunity, Maternally-Acquired; D007114:Immunization; D007115:Immunization Schedule; D007116:Immunization, Passive; D007074:Immunoglobulin G / Q000008:administration & dosage; D007938:Leukemia / Q000517:prevention & control / Q000662:veterinary*; D007942:Leukemia, Experimental / Q000517:prevention & control; D051379:Mice; D008806:Mice, Inbred AKR / Q000276:immunology*; D014764:Viral Proteins / Q000276:immunology*
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D014764:Viral Proteins
Spontane Leukämie der AKR-Mäuse. Erfolgreiche passive Immunisierung mit Ziegen-Antikörper gegen isoliertes Glykoprotein gp71 des Friend-Leukämie-Virus.