[Toxic reactions to gold salts with severe enterocolitis in a patient with rheumatoid arthritis].
A case of severe enterocolitis which occurred on initiation of chrysotherapy for rheumatoid arthritis is reported. The patient, a male aged 50 years, suffered from dramatic diarrhea for several weeks. Biopsy specimens from the stomach, ileum and colon revealed signs of inflammation. Later, general toxicodermia, mouth ulcers, blood eosinophilia and asymptomatic proteinuria were observed. After several months all the side effects disappeared. The toxicodermia was the most persistent.
D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D001835:Body Weight; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced*; D006046:Gold / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D013280:Stomatitis / Q000139:chemically induced
D006046:Gold
Réactions toxiques aux sels d'or avec entérocolite grave chez un homme atteint d'une polyarthrite rhumatoïde