[Serum antigammaglobulin antibodies in patients with cancer of the uterine cervix (author's transl)].
Agar immunoprecipitation with homologous and heterologous IgG aggregates and hemagglutination with sensitized sheep red blood cells showed that high percentage of patients with cancer of the uterine cervix have antigammaglobulin antibodies in their blood serum. In order to confirm the Ig type of the studied antibodies, sera of cancer patients were fractionated by gel filtration on Sephadex G200 by pH = 4.0. The positive hemagglutination and precipitation activities of the first gel filtration peaks (comprising the 19 S macroglobulin) as the lack of such activity after treatment with 2-mercaptoethanol confirmed the antibodies to be of IgM type.
D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis*; D002583:Uterine Cervical Neoplasms / Q000276:immunology*
D000888:Antibodies, Anti-Idiotypic; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Serum Antigammaglobulin-Antikörper bei Patienten mit Carcinoma colli uteri.