[The fertility of trisomy 21 sufferers. One case (author's transl)].
A case of pregnancy in a patient with trisomy 21 with birth of a hypotrophic infant, with a normal caryotype but multiple malformations. This case illustrates the limitations on antenatal diagnosis by amniocentesis. Study of the literature confirms the unfavourable foetal prognosis as a result of the risk of transmission of the chromosomal abnormality and, secondly, the prevalence of incest.
D000015:Abnormalities, Multiple / Q000209:etiology*; D000328:Adult; D000649:Amniocentesis; D004314:Down Syndrome / Q000503:physiopathology*; D005260:Female; D005298:Fertility; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications
Fécondité des sujets trisomiques 21. Une observation.