title: Analogs and conversion products of streptozotocin.
abstract: Reduction of the nitroso group in streptozotocin (1a) has led to cyclized products rather than a semicarbazide (1c). Some analogs (1e, 9a, 9b, 9c and 9d) of streptozotocin in which the nitroso group was replaced by other groups have been prepared.
mesh_terms: D000215:Acylation; D000818:Animals; D002384:Catalysis; D002460:Cell Line; D007939:Leukemia L1210 / Q000503:physiopathology; D007942:Leukemia, Experimental / Q000188:drug therapy; D051379:Mice; D010084:Oxidation-Reduction; D013311:Streptozocin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology
chemical_list: D013311:Streptozocin