title: [Deformities of the spine and ribs in embryologically related malformations of the heart with cyanosis].
abstract: Three cases of severe costovertebral deformities together with embryologically related cardiac malformations (Fallots Tetralogy and Truncus arteriosus communis) are presented. Two patients died because of their thoracic deformities and limited respiratory function. Relationships to similar bizarre veretebral anomalies are discussed. The cause is probably a teratogenic agent, acting between the fifth to eight embryologic week.
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000196:embryology*; D004374:Ductus Arteriosus, Patent / Q000196:embryology*; D005260:Female; D005865:Gestational Age; D006330:Heart Defects, Congenital / Q000196:embryology*; D006343:Heart Septal Defects / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011014:Pneumonia / Q000150:complications; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012272:Ribs / Q000002:abnormalities*; D013131:Spine / Q000002:abnormalities*; D013577:Syndrome; D013771:Tetralogy of Fallot / Q000150:complications
vernacular_title: Wirbelsäulen-und Rippenmissbildungen bei embryologisch verwandten zyanotischen Herzfehlern