Lymphocyte and fibroblast chalones: some chemical properties.
Experiments with lymphocyte and fibroblast chalones indicate that they are complexed strongly with RNA in tissue extracts; have a molecular weight of less than 10,000 and more than 1,000 daltons, and probably about 5,000 daltons; are strongly cationically charged; and contain mannose and perhaps other carbohydrates.
D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D005347:Fibroblasts / Q000187:drug effects; D006020:Glycopeptides / Q000032:analysis; D006131:Growth Inhibitors / Q000302:isolation & purification / Q000494:pharmacology; D007526:Isoelectric Point; D008214:Lymphocytes / Q000187:drug effects; D008358:Mannose / Q000032:analysis; D008970:Molecular Weight; D012313:RNA / Q000378:metabolism
D006020:Glycopeptides; D006131:Growth Inhibitors; D012313:RNA; D008358:Mannose