[Chemical and radioisotope studies of the metabolism in mineralized tissues following use of calcium-, phosphate-, and fluoride-containing toothpastes].
During experimental research work carried out on animals with a view to clearing up the caries-forming processes, metabolic disturbances could be detected in the hard tissues of teeth after administering a cariogenic diet. The aim of the present work was to investigate the effects of tooth-pastes with calcium, phosphate and fluoride content upon changes in metabolic processes, and thus to clarify the mechanism of the anti-cariogenic effect exerted by fluoride tooth-pastes.
D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D002132:Calcium Radioisotopes; D002250:Carbon Radioisotopes; D003731:Dental Caries / Q000378:metabolism*; D004037:Diet, Cariogenic; D005460:Fluorides, Topical / Q000494:pharmacology*; D008297:Male; D010710:Phosphates / Q000494:pharmacology*; D010761:Phosphorus Radioisotopes; D051381:Rats; D014070:Tooth / Q000378:metabolism*; D014100:Toothpastes
D002132:Calcium Radioisotopes; D002250:Carbon Radioisotopes; D005460:Fluorides, Topical; D010710:Phosphates; D010761:Phosphorus Radioisotopes; D014100:Toothpastes; D002118:Calcium
Chemische and radioisotopische Untersuchungen des Stoffwechsels in mineralisierten Geweben der Ratte nach Anwendunkg kalzium-, phosphat-, und fluoridhaltiger Zahnpasten