[The effectiveness of vasopressors and vasodilators for pharmaco-dynamic renal angiography (author's transl)].
9,450 radiographs of 355 patients were analysed in order to determine the diagnostic values of pharmaco-dynamic renal angiography. In each case renal angiography was performed by a conventional techinique as the basis for a clinical experimental study of the effectiveness of a-renergic and cholinergic drugs. The comparison showed unequivocally that pharmacodynamic methods may increase the value of renal angiography. Vasopressors alter the pressure gradient during the arterial phase and improve filling of neovascular areas, which are themselves unreactive. The value of the vasodilators depends on the increased contrast values during the parenchymatous and venous phases of the angiogram. In this way structural changes in tne renal parenchyma and pathological changes in the veins can be emphasised. The value of adrenergic drugs consists in increasing the vascular supply to various tumours, focal inflammatory disease and renal contusion, whereas cholinergic drugs are suitable for improving the demonstration of parenchymal lesions, such as tumours, cysts, abscesses, tuberculomas and localised renal trauma. The results indicate clearly that pharmaco-dynamic methods represent an integral part of renal angiography.
D000109:Acetylcholine / Q000494:pharmacology; D000230:Adenocarcinoma / Q000098:blood supply / Q000000981:diagnostic imaging; D000236:Adenoma / Q000098:blood supply / Q000000981:diagnostic imaging; D000293:Adolescent; D000368:Aged; D000792:Angiography / Q000379:methods*; D001027:Aortography / Q000379:methods; D006801:Humans; D007668:Kidney / Q000098:blood supply; D007674:Kidney Diseases / Q000000981:diagnostic imaging*; D052177:Kidney Diseases, Cystic / Q000000981:diagnostic imaging; D007680:Kidney Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging; D008875:Middle Aged; D009638:Norepinephrine / Q000494:pharmacology; D011704:Pyelonephritis / Q000000981:diagnostic imaging; D012039:Regional Blood Flow / Q000187:drug effects; D014662:Vasoconstrictor Agents / Q000494:pharmacology*; D014665:Vasodilator Agents / Q000494:pharmacology*
D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents; D000109:Acetylcholine; D009638:Norepinephrine
Effektivität von Vasopressoren und Vasodilatoren in der pharmakodynamischen Nierenangiographie