[Increase in the rate of anaerobic glycolysis as an index of hypoxia in hemorrhagic shock].
A rate of anaerobic glycolysis and the activity of several enzymes involved were studied in brain, heart, liver and small intestine of rabbits in hemorrhagic shock. In hemorrhagic shock at 45 mm of m. c. the rate of glycolysis was increased in liver tissue and intestine, at 35 mm of m.c.--in liver tissue, intestine and brain, at 26 mm of m.c.--in all the tissues studied. The enzymatic activity did not alter markedly. The possible mechanism of the increased rate of anaerobic glycolysis is discussed.
D000818:Animals; D001794:Blood Pressure; D001921:Brain / Q000201:enzymology / Q000378:metabolism; D002682:Chinchilla; D005956:Glucose-6-Phosphate Isomerase / Q000378:metabolism; D006019:Glycolysis; D006593:Hexokinase / Q000378:metabolism; D007421:Intestine, Small / Q000201:enzymology / Q000378:metabolism; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D009206:Myocardium / Q000201:enzymology / Q000378:metabolism; D010732:Phosphofructokinase-1 / Q000378:metabolism; D011817:Rabbits; D012771:Shock, Hemorrhagic / Q000201:enzymology / Q000378:metabolism*
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D006593:Hexokinase; D010732:Phosphofructokinase-1; D005956:Glucose-6-Phosphate Isomerase
Uvelichenie skorosti anaérobnogo glikoliza kak pokazatel' gipoksii pri gemorragicheskom shoke.