Murine B lymphocyte heterogeneity: distribution of complement receptor-bearing and minor lymphocyte-stimulating B lymphocytes among cells with different densities of total surface Ig and IgM.
The distribution of complement receptor-bearing (CR+) and minor lymphocyte-stimulating (Mls)-defined lymphocyte-activating determinants (LAD) among B lymphocytes with different densities of total surface immunoglobulin (sIg) and sIgM was determined. B lymphocytes that bore intermediate densities of sIg and low densities of sIgM had the highest frequency of CR+ cells and were the most active in expressing Mls-defined LAD. The distribution of these and other surface markers on B-lymphocyte subpopulations is discussed.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D001665:Binding Sites; D003165:Complement System Proteins; D005455:Fluorescent Antibody Technique; D007075:Immunoglobulin M; D007959:Lymphocyte Culture Test, Mixed; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008811:Mice, Inbred DBA; D011947:Receptors, Antigen, B-Cell
D007075:Immunoglobulin M; D011947:Receptors, Antigen, B-Cell; D003165:Complement System Proteins