title: [The Sézary syndrome].
abstract: A case of the rare Sézary syndrome is described. The Sézary syndrome is a lymphoproliferative disorder of the skin, the lymph nodes, and to a smaller extent the bone marrow, which begins with erythrodermia. In the blood, strange circulating lymphocytes with a "cerebriform" chromatin structure and T-cell properties are found. The disease is primarly benign but may become malignant. The origin is unknown. Endogenic and exogenic factors are considered and relationships to other cutaneous lympho-proliferative diseases and treatment are discussed.
mesh_terms: D002699:Chlorambucil / Q000627:therapeutic use; D003873:Dermatitis, Exfoliative / Q000188:drug therapy; D006644:Histiocytes; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000188:drug therapy*; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis; D011241:Prednisone / Q000627:therapeutic use; D013577:Syndrome
chemical_list: D002699:Chlorambucil; D011241:Prednisone
vernacular_title: Das Sézary-Syndrom