Thymineless bacteriophage induction in Staphylococcus aureus. II. Specific transduction of constitutive and inducible erythromycin resistance.
Specific transduction of inducible (eroA) and constitutive (eroB) erythromycin resistance is mediated by thymineless induced lysates from derivatives of Staphylococcus aureus strain 8325(N)thy. Both loci can coexist in the same cell but segregate by transduction or transformation. The gene(s) is probably integrated in the recipient chromosome and excised at thymine starvation.
D002876:Chromosomes, Bacterial; D004269:DNA, Bacterial / Q000032:analysis; D004270:DNA, Circular / Q000032:analysis; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000494:pharmacology*; D005796:Genes; D008242:Lysogeny; D009154:Mutation; D013204:Staphylococcus Phages / Q000254:growth & development*; D013211:Staphylococcus aureus / Q000032:analysis / Q000187:drug effects / Q000378:metabolism*; D013941:Thymine / Q000378:metabolism*; D014161:Transduction, Genetic; D014170:Transformation, Genetic; D014466:Ultraviolet Rays; D014779:Virus Replication
D004269:DNA, Bacterial; D004270:DNA, Circular; D004917:Erythromycin; D013941:Thymine