[Effect of a 22-day space flight on the metabolism of rat skeletal muscle tissue].
Skeletal muscles of flight rats showed no changes in the content of glycogen, adenosine triphosphatase activity of myosin and protein content in protein fractions (except the T fraction where the protein content increased on the 1st and returned to the normal on the 26th postflight day). On the 1st postflight day activities of aminotransferases and lactate dehydrogenase of sarcoplasmatic proteins were elevated and the isoenzyme spectrum of LDH was changed as if in muscular atrophy. The amount of free amino acids in muscles was lowered. On the 26 the postflight day the enzymic activity of sarcoplasmatic proteins remained increased whereas the isoenzyme spectrum of LDH returned to the normal and the amount of free amino acids grew significantly. In the microsomal fraction of muscles the phospholipid content decreased on the 1st and returned to the normal on the 26th postflight day.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000410:Alanine Transaminase / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D009124:Muscle Proteins / Q000378:metabolism; D009132:Muscles / Q000201:enzymology / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism; D051381:Rats; D013026:Space Flight; D013997:Time Factors
D000596:Amino Acids; D007527:Isoenzymes; D009124:Muscle Proteins; D010743:Phospholipids; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000251:Adenosine Triphosphatases
Vliianie 22-sutochnogo kosmicheskogo poleta na metabolizm tkani skeletnykh myshts u krys