[HCO3-sensitive adenosinetriphosphatase from ascites tumour cells].
HCO3--sensitive ATPase was found in nuclear and plasma membrane fractions of Ehrlich ascites tumour cells and lymphoma NK cells. HCO3--ATPase was not sensitive to monovalent cations and to ouabain (10(-4) M). The 60 mM HCO3- is the concentration of maximal activation of the HCO3--sensitive ATPase. The HCO3--sensitive ATPase was inhibited by anions in the sequence: SCN- greater than F- greater than ClO4- greater J-. The anions Br-, NO3-, HSO3- were not effective.
D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors*; D000818:Animals; D000838:Anions; D001639:Bicarbonates / Q000494:pharmacology*; D002286:Carcinoma, Ehrlich Tumor / Q000201:enzymology*; D002460:Cell Line; D002462:Cell Membrane / Q000187:drug effects / Q000201:enzymology; D002467:Cell Nucleus / Q000187:drug effects / Q000201:enzymology; D007700:Kinetics; D008223:Lymphoma / Q000201:enzymology*; D051379:Mice
D000838:Anions; D001639:Bicarbonates; D000251:Adenosine Triphosphatases