The activity of four antimicrobial agents. Including three nitroimidazole compounds, against Bacteroides sp.
Forty strains of Bacteroides sp. were tested against three nitroimidazole compounds, metronidazole, tinidazole and nimorazole and the aminoglycosidic antibiotic spectinomycin. The effect of altering the inoculum and the presence of serum upon the minimum inhibitory concentration (MIC) was also noted. The three nitroimidazole compounds were all very active (average MIC = circa 0.25 mg/l). Tinidazole was twofold more active. The MIC of spectinomycin was 32 mg/l.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001439:Bacteroides / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009554:Nimorazole / Q000494:pharmacology; D009593:Nitroimidazoles / Q000494:pharmacology*; D000198:Spectinomycin / Q000494:pharmacology*; D014011:Tinidazole / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D009593:Nitroimidazoles; D014011:Tinidazole; D008795:Metronidazole; D009554:Nimorazole; D000198:Spectinomycin