Investigation on Huntington's disease. III. Biochemical observations, a possibly predictive test?
The possible biochemical basis underlying the aetiology and pathogenesis of Huntington's disease (H.D.) is discussed. The development of a predictive test for presymptomatic detection of the disorder, based on measurement of serum caeruloplasmin and serum dopamine beta-hydroxylase (DBH) is also described. Possible means of appraising the proposed test are suggested.
D002570:Ceruloplasmin / Q000032:analysis*; D004299:Dopamine beta-Hydroxylase / Q000097:blood*; D006801:Humans; D006816:Huntington Disease / Q000097:blood* / Q000201:enzymology
D004299:Dopamine beta-Hydroxylase; D002570:Ceruloplasmin