[Cell mediated immunity in sarcoidosis patients].
In vitro tests, lymphocyte transformation tests, and leukocyte migration inhibition tests were carried out on nineteen patients with different stages of sarcoidosis. In all patients there was found a defect of cell-mediated immunity, which was most strongly pronounced in the remission phase of the disease. It is believed that the disturbance of cell-mediated immunity is a result of the disease. It is possible for such a disturbance to be intensified in the further course of disease. It appears that this disturbance may be compensated for by the system of B lymphocytes, through humoral antibodies, because clinical phenomena manifest in the patients and corresponding to the deficiency of immunity demonstrated in vitro could not be observed.
D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D007165:Immunosuppression Therapy; D012075:Remission, Spontaneous; D012507:Sarcoidosis / Q000276:immunology*
Zellvermittelte Immunität bei Sarkoidosekranken