title: [Classification, diagnosis, and therapy of immunological aspects of disease according to reaction types].
abstract: The classical division of the immune reactions into an immediate humoral type and a cellular late type is left in favour of a classification in 4 forms of reaction according to Gell and Coombs. This classification allows of a by far more reasonable coordination of the diagnostic measures as well as aimed therapeutic conclusions. In detail are differed: type I as anaphylaxis and reagin type (mediator-substance-type), example-anaphylactic shock and asthma; type II as cytotoxic type (cytotoxic antibodies), example-Coombs-positive haemolytic anaemia; type III as immune complex type, examples-serum disease, Arthus-reaction, glomerulonephritis; type IV as type of the cellular immune reactions. Combinations and transitions are possible in the same way as a further sub-classification of the types. It is demonstrated as by the combination of in-vitro-tests, skin tests and, perhaps, bioptic investigations the type is to be determined as far as possible. Only this allows an aimed and reasonable therapy.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000707:Anaphylaxis / Q000175:diagnosis; D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis; D019867:Anti-Glomerular Basement Membrane Disease / Q000175:diagnosis; D001183:Arthus Reaction / Q000175:diagnosis; D001249:Asthma / Q000175:diagnosis; D005921:Glomerulonephritis / Q000175:diagnosis; D006801:Humans; D007105:Immune Complex Diseases / Q000175:diagnosis; D007154:Immune System Diseases / Q000145:classification / Q000175:diagnosis / Q000628:therapy; D007109:Immunity; D007111:Immunity, Cellular; D007167:Immunotherapy; D012713:Serum Sickness / Q000175:diagnosis; D012882:Skin Tests
chemical_list: D000305:Adrenal Cortex Hormones
vernacular_title: Einteilung, Diagnostik und Therapie immunologischer Krankheitsbilder nach Reaktionstypen