[Comparative studies on Bi-Nerisona cream (diflucortolone valerinate + chlorquinaldol) and on a combination preparation (betamethasone valerinate + gentamicin + tolnaftate + clioquinol) in a double-blind trial].
Bi-Nerisone cream and a control preparation, also in the form of a cream, have been clinically tested on 343 patients by means of a double blind study. Equilvalent results were obtained without registering any significant statistical differences, a finding, however, proving to be of great importance as Bi-Nerisone only contains two active substances (Diflucortolone valerat + Chlorquinaldol), whereas the control preparation contains a total of four (Betamethasone valerate + Gentamycin + Tolnaftate + Clioquinol).
D001624:Betamethasone Valerate / Q000627:therapeutic use; D002750:Chlorquinaldol / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D007464:Clioquinol / Q000627:therapeutic use; D003872:Dermatitis / Q000188:drug therapy*; D004311:Double-Blind Method; D004338:Drug Combinations; D005448:Fluocortolone / Q000031:analogs & derivatives / Q000627:therapeutic use*; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D009824:Ointments; D011244:Pregnadienediols / Q000627:therapeutic use*
D004338:Drug Combinations; D005839:Gentamicins; D009824:Ointments; D011244:Pregnadienediols; D005448:Fluocortolone; D007464:Clioquinol; D001624:Betamethasone Valerate; D002750:Chlorquinaldol
Vergleichende Untersuchung von Bi-Nerisona -Creme (Diflucortolonvalerianat + Chlorquinaldol) und einem Kombinationspräparat (Betamethasonvalerianat + Gentamycin + Tolnaftat + Clioquinol) im Doppelblindversuch.