title: A radioimmunoassay for isoniazid.
abstract: A sensitive radioimmunoassay is described, for measuring isoniazid in therapeutic and subtherapeutic concentrations. This radioimmunoassay was used in an exploratory clinical study to measure, as a function of time, the concentration of this drug in plasma of patients receiving isoniazid therapy.
mesh_terms: D000107:Acetylation; D000636:Aminosalicylic Acids / Q000097:blood; D003429:Cross Reactions; D006801:Humans; D007538:Isoniazid / Q000031:analogs & derivatives / Q000097:blood* / Q000378:metabolism / Q000627:therapeutic use; D007539:Isonicotinic Acids / Q000097:blood; D009536:Niacinamide / Q000097:blood; D011863:Radioimmunoassay / Q000379:methods*; D014316:Tritium; D014376:Tuberculosis / Q000188:drug therapy
chemical_list: D000636:Aminosalicylic Acids; D007539:Isonicotinic Acids; D014316:Tritium; D009536:Niacinamide; D007538:Isoniazid