[On the carcinogenic action of N-nitroso-compounds. 5th Communication: acetoxymethyl-methyl-nitrosamine (author's transl)].
After oral application of 3.5 and 1.75 mg/kg Acetoxymethyl-Methyl-nitrosamine to Sprague-Dawley rats twice weekly, more than 80% of the animals developed squamous cell carcinomas of the forestomach after 6 months.
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced; D004128:Dimethylnitrosamine / Q000031:analogs & derivatives / Q000494:pharmacology*; D008297:Male; D009374:Neoplasms, Experimental / Q000139:chemically induced; D009602:Nitrosamines / Q000494:pharmacology*; D051381:Rats; D013274:Stomach Neoplasms / Q000139:chemically induced*; D013997:Time Factors
D009602:Nitrosamines; D004128:Dimethylnitrosamine
Zur carcinogenen Wirkung von N-Nitroso-Verbindungen. 5. Mitteilung: Acetoxymethyl-Methyl-Nitrosamin