[Electron microscopical findings of the myocardium in Fallot's disease and of the ventricular septal defects (author's transl)].
Ultrastructural quantitative and qualitative investigations of the myocardium of 7 children with Fallot's disease and 3 children with a ventricular septal defect (VSD) have shown bizarre nuclei and a slight increase in the myofibril share of the volume (Fallot's disease: 51.22%; VSD: 56.85%). This may be interpreted as a sign of a cellular hypertrophy. The mitochondria have a proportion of 35.07% and 33.75%, respectively. The glycogen content is relatively high. The lipofuscin bodies originate mainly from mitochondria having a percentage of 1.43 and 1.67, respectively. Particular signs of a lesion could not be observed. From the ultrastructural findings on the morphology of heart muscle cells it can be deduced that operations of vitia may be safely carried out.
D000293:Adolescent; D006332:Cardiomegaly / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006003:Glycogen / Q000032:analysis; D006345:Heart Septal Defects, Ventricular / Q000473:pathology*; D006801:Humans; D007223:Infant; D008062:Lipofuscin; D008297:Male; D008854:Microscopy, Electron; D008929:Mitochondria, Heart / Q000648:ultrastructure; D009206:Myocardium / Q000648:ultrastructure*; D013771:Tetralogy of Fallot / Q000473:pathology*
D008062:Lipofuscin; D006003:Glycogen
Elektronenmikroskopische Befunde der Herzmuskulatur beim Morbus Fallot und Ventrikelseptumdefekt.