[Effect of hydrocortisone on the fractional makeup of acid mucopolysaccharides in the aorta].
Five components of the acid mucopolysaccharides were isolated from rabbit aorta; these were hyaluronic acid, heparitin sulphate, chondroitin sulphate A, C and B. Prolonged administration of hydrocortisone increased the hyaluronic acid concentrations and decreased the level of heparitin sulphate. Fifteen days after the cessation of the hormone administration the aortic tissue proved to contain a lower percentage of chondroitin sulphate A, C anc B.
D000818:Animals; D001011:Aorta / Q000032:analysis / Q000187:drug effects* / Q000378:metabolism; D002809:Chondroitin Sulfates / Q000032:analysis; D006025:Glycosaminoglycans / Q000032:analysis / Q000378:metabolism*; D006497:Heparan Sulfate / Q000032:analysis; D006820:Hyaluronic Acid / Q000032:analysis; D006854:Hydrocortisone / Q000494:pharmacology*; D008297:Male; D011817:Rabbits; D013997:Time Factors
D002809:Chondroitin Sulfates; D006025:Glycosaminoglycans; D006497:Heparan Sulfate; D006820:Hyaluronic Acid; D006854:Hydrocortisone
Vliianie gidrokortizona na fraktsionnyĭ sostav kislykh mukopolisakharidov aorty