Knuckle pads, leukonychia, deafness, and keratosis palmoplantaris: report of a family.
A family is described in which knuckle pads, leukonychia, deafness, and keratosis palmoplantaris are present as a syndrome is several members. This is the second such family reported demonstrating that keratosis palmoplantaris is part of the syndrome. Inheritance pattern is probably autosomal dominant.
D000328:Adult; D002648:Child; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D003638:Deafness; D005260:Female; D005799:Genes, Dominant; D006311:Hearing Disorders / Q000235:genetics; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009264:Nails, Malformed; D012868:Skin Abnormalities; D013577:Syndrome; D014034:Toes