[Participation of Na, K-ATPase in the mechanism of isotonic fluid absorption by the epithelium of the frog gallbladder].
In experiments on the isolated frog gallbladders it was shown that addition of ouabain (1.10(-4) M) or noradrenaline 3.10(-6) M) into the incubation Ringer solution from the serous surface of the gallbladder and also replacement of K+ in the solution for the equivalent quantity of Na+ ions caused a reduction of the absorption of isotonic fluid by the epithelium and a fall of the Na,K-ATPase activity in its cells. Noradrenaline also cased a reduction of Mg-ATPase activity. A significant positive correlation was found between the transport rate of the isotonic fluid by the epithelium and the Na,K-ATPase activity in its cells.
D000042:Absorption; D000251:Adenosine Triphosphatases / Q000502:physiology*; D000818:Animals; D001001:Anura; D001692:Biological Transport / Q000187:drug effects; D004789:Enzyme Activation / Q000187:drug effects; D004848:Epithelium / Q000378:metabolism; D005704:Gallbladder / Q000378:metabolism*; D066298:In Vitro Techniques; D007552:Isotonic Solutions; D009638:Norepinephrine / Q000494:pharmacology; D010042:Ouabain / Q000494:pharmacology; D011188:Potassium; D012964:Sodium
D007552:Isotonic Solutions; D010042:Ouabain; D012964:Sodium; D000251:Adenosine Triphosphatases; D011188:Potassium; D009638:Norepinephrine
Ob uchastii Na, K-ATF-azy v mekhanizme vsasyvaniia izotonicheskoĭ zhidkosti épiteliem zhelchnogo puzyria liagushki.