[Action of 5-bromodeoxyuridine as a function of time on the aspect of chromosomes. Attempt at interpretation].
The different aspects of chromosomes in culture with B.U.D.R. are described. The times of B.U.D.R. action are 1/2, 1, 2 and 3 mitotic cycles. Four different aspects are obtained. For each time, 250 mitosis are studied, and classified. The results seem to confirm the semiconservative replication.
D001973:Bromodeoxyuridine / Q000494:pharmacology*; D002478:Cells, Cultured; D002868:Chromosomal Proteins, Non-Histone / Q000096:biosynthesis; D002875:Chromosomes / Q000187:drug effects*; D004261:DNA Replication; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects; D008938:Mitosis / Q000187:drug effects; D013997:Time Factors
D002868:Chromosomal Proteins, Non-Histone; D001973:Bromodeoxyuridine
Action de la 5-bromodésoxyuridine en fonction du temps sur l'aspect des chromosomes. Essai d'interprétation