[The inhibition of various bacterial proteinases with natural proteinase inhibitiors(author's transl)].
Proteus mirabilis, citrobacter intermedius, staphylococcus aureus haemolyticus and staphylococcus albus produce extracellualr proteinases with maximum activity at pH 7.8. These proteinases are inhibited practically completely by human and animal blood serum. This inhibitory activity of human serum is caused by alpha2-macroglobulin. Ovomucoid showed nearly the same inhibitory activity as alpha2-macroglobulin.
D000818:Animals; D001419:Bacteria / Q000187:drug effects / Q000201:enzymology*; D001769:Blood; D002417:Cattle; D002954:Citrobacter / Q000201:enzymology; D004285:Dogs; D005110:Extracellular Space / Q000201:enzymology; D006801:Humans; D008259:Macroglobulins / Q000494:pharmacology; D011480:Protease Inhibitors; D011513:Proteus mirabilis / Q000201:enzymology; D011549:Pseudomonas / Q000201:enzymology; D013210:Staphylococcus / Q000201:enzymology
D008259:Macroglobulins; D011480:Protease Inhibitors
Zur Hemmbrakeit verschiedener Bakterienproteinasen durch natürlichs Proteinaseninhibitoren.