title: Does ATP decrease exponentially during red cell aging?
abstract: The precise changes in adenosine triphosphate (ATP) during red cell aging have not been established. Studies of ATP content based on cell density, a presumptive index of red cell age, observations in anemic subjects in whom age-dependent hemeolysis may occur and studies of the loss of metabolic capability with aging, suggest that the reduction in red cell ATP may be a continuous process, approximating a negative expotential function. Several experimental approaches could be used to support or refute this hypothesis.
mesh_terms: D000255:Adenosine Triphosphate / Q000097:blood*; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000378:metabolism*; D006019:Glycolysis; D006801:Humans; D008433:Mathematics
chemical_list: D000255:Adenosine Triphosphate