[Action of 9-aminoacridine on the axonal membrane of the cockroach [Periplaneta americane L].
When applied externally to the cockroach giant axon, the substance 9-aminoacridine diminishes both sodium and potassium conductane increases. The K+ CURRENT DIMINUTION SHOULD BE DONE TO A 9AA-induced potassium inactivation or to an accumulation of K+ ions in the periaxonal space.
D000166:Acridines / Q000494:pharmacology*; D000818:Animals; D001369:Axons / Q000187:drug effects*; D001692:Biological Transport / Q000187:drug effects; D002462:Cell Membrane / Q000187:drug effects*; D003058:Cockroaches; D008564:Membrane Potentials / Q000187:drug effects*; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism
D000166:Acridines; D012964:Sodium; D011188:Potassium
Action de la 9-aminoacridine sur la membrane axonale de la Blatte [Periplaneta americana L]