[Therapeutic embolisation of visceral arteries. Animal experiments, early clinical experience and introduction of a new embolising material (author's transl)].
In order to compare the effectiveness and suitability of the most commonly used embolising materials--autologous blood clot, either pure or modified by epsilon-amino-caproic acid, gelatin, or fibrin foam--a series of experiments was carried out using the renal arteries of rabbits. Our own experience and the information in the literature indicate that there is at present no optimal and lasting material for embolisation. A new radioopaque for am consisting of a silicone elastomer has been found to be superior to all other materials, without any evidence of complication arising from it. Contrary to present views, it has been shown that the effect of embolisation is best demonstrated scintigraphically; angiography immediately after embolisation does not provide the necessary informatin (spasm, further thrombosis). The results of animal experiments and toxicity studies indicated that the substance can be used as suitable embolising material in patients, provided the indications are strictly controlled.
D000792:Angiography / Q000379:methods; D000818:Animals; D001158:Arteries / Q000502:physiology; D001794:Blood Pressure; D004621:Embolization, Therapeutic / Q000379:methods*; D007668:Kidney / Q000000981:diagnostic imaging; D011817:Rabbits; D011877:Radionuclide Imaging; D013997:Time Factors
Therapeutische Embolisation von Organarterien--Tierexperimentelle Untersuchungen, erste klinische Erfahrungen, Einführung eines neuen Embolisationsmaterials.