title: [The role of serotonin in one of the types of aggressive behavior--"predatory aggression"].
abstract: Electrolytic lesion of the midbrain raphe nuclei in rats, lowering serotonin level in the forebrain, elicited mouse-killing behavior. After the lesion, 50% of previously non-killers rats became mouse-killers. 5-Hydroxytryptophan (100 mg/kg) administration elevated serotonin level to normal values and completely blocked predatory aggression. p-Chlorophenylalanine produced obvious reduction in brain serotonin and slightly stimulated aggressive behavior. These results suggest that the brain serotonin participates as an inhibitory factor in mouse-killing behavior in rats.
mesh_terms: D006916:5-Hydroxytryptophan / Q000494:pharmacology; D000374:Aggression / Q000502:physiology*; D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects; D010134:Fenclonine / Q000494:pharmacology; D006801:Humans; D008297:Male; D008636:Mesencephalon / Q000502:physiology*; D009433:Neural Inhibition; D051381:Rats; D012154:Reticular Formation / Q000502:physiology; D012701:Serotonin / Q000032:analysis / Q000502:physiology*; D013687:Telencephalon / Q000032:analysis / Q000502:physiology*
chemical_list: D012701:Serotonin; D006916:5-Hydroxytryptophan; D010134:Fenclonine
vernacular_title: O roli serotonina v odnom iz vidov agressivnogo povedeniia--"agressii khishchnika".