47,XXX karyotype obtained by amniocentesis.
A 29-year-old pregnant patient, gravida 4, para 3, sought genetic counseling because of a daughter who had Down's syndrome. Amniotic fluid obtained by amniocentesis indicated the fetal karyotype to be 47,XXX. The pregnancy was terminated and the karyotype was confirmed by typing venous blood from the fetus and the finding of double Barr bodies in the histologic sections of fetal tissue.
D000028:Abortion, Induced; D000649:Amniocentesis; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000235:genetics; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D012729:Sex Chromosome Aberrations / Q000175:diagnosis*