title: [Clinical and experimental studies on the effect of benzoyl peroxide in the treatment of acne].
abstract: In recent years benzoylperoxide has become increasingly popular in the treament of acne. Beside of a dermal irritative and keratolytic effect this was attributed to the bacteriostatic quality of the substance. By in vitro autoradiography and determination of skin surface lipids in benzoylperoxide=treated skin also a sebostatic effect could be observed. Scanning electron microscopy showed that benzoylperoxide influences the horny layer in a similar way like salicylic acid.
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy*; D000293:Adolescent; D001585:Benzoyl Peroxide / Q000627:therapeutic use*; D055598:Chemical Phenomena; D002621:Chemistry; D004817:Epidermis / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D005260:Female; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use; D050356:Lipid Metabolism; D008297:Male; D008855:Microscopy, Electron, Scanning; D010545:Peroxides / Q000627:therapeutic use*; D012867:Skin / Q000378:metabolism / Q000648:ultrastructure
chemical_list: D005230:Fatty Acids, Nonesterified; D007641:Keratolytic Agents; D010545:Peroxides; D001585:Benzoyl Peroxide
vernacular_title: Klinische und experimentelle Untersuchungen über die Wirkung von Benzoylperoxid in der Behandlung der Akne.