title: Isolation and identification of the conidial germination factor of Neurospora crassa.
abstract: The germination-essential substance (germination factor [GF]) that is lost from conidia of Neurospora crassa on exposure to solutions of low water activity has been isolated and identified as a group of iron-transport compounds, or siderochromes. The principal siderochrome of conidia is ferricrocin, a cyclic hexapeptide. A closely related substance, ferrichrome C, is tentatively identified as a minor constituent. The same substances are also present in extracts of mycelium along with small amounts of a third siderochrome, which has not been identified. The GF activity of culture filtrates is due to coprogen, the only siderochrome previously identified with N. crassa.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D005291:Ferrichrome / Q000032:analysis; D005656:Fungal Proteins / Q000032:analysis; D006133:Growth Substances; D009491:Neurospora / Q000032:analysis*; D009492:Neurospora crassa / Q000032:analysis* / Q000254:growth & development; D010456:Peptides, Cyclic / Q000032:analysis / Q000302:isolation & purification; D013172:Spores, Fungal / Q000254:growth & development
chemical_list: D005656:Fungal Proteins; D006133:Growth Substances; D010456:Peptides, Cyclic; D005291:Ferrichrome