[Effect of an ovine pineal gland extract on prolactin release in vitro].
Defatted ovine pineal powder is submitted to acetic acid extraction followed by chromatographic separation. The extracted material and one of the two separated fractions inhibit the secretion of PRL by pituitary cells in monolayer culture. Both basal and TRH stimulated secretions are reduced.
D000818:Animals; D002478:Cells, Cultured; D066298:In Vitro Techniques; D010870:Pineal Gland; D010903:Pituitary Gland, Anterior / Q000166:cytology / Q000378:metabolism*; D011388:Prolactin / Q000378:metabolism*; D012756:Sheep; D013973:Thyrotropin-Releasing Hormone / Q000378:metabolism; D014020:Tissue Extracts / Q000494:pharmacology*
D014020:Tissue Extracts; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin
Influence d'un extrait de glandes pinéales ovines sur la libération de prolactine in vitro.