title: Clindamycin and diarrhea.
abstract: Of 298 outpatients receiving clindamycin for a variety of indications, diarrhea developed in ten (3.4%); none were diagnosed as having pseudo-membranous colitis. This is well within the range of relative frequencies of diarrhea development (0% to 22.2%) reported in 45 previous studies. Reliance solely on computer-recorded instances of diarrhea yielded a substantial underestimate of diarrhea occurence, but the rate was still significantly higher (P less than .05) in clindamycin users than in nonusers.
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002981:Clindamycin / Q000009:adverse effects* / Q000627:therapeutic use; D003201:Computers; D003967:Diarrhea / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008499:Medical Records / Q000592:standards; D008875:Middle Aged; D012874:Skin Diseases, Infectious / Q000188:drug therapy
chemical_list: D002981:Clindamycin