Inhibition of insulin biosynthesis by alloxan, streptozotocin, and N-nitrosomethylurea.
D000496:Alloxan / Q000494:pharmacology*; D000818:Animals; D002850:Chromatography, Gel; D003864:Depression, Chemical; D007328:Insulin / Q000096:biosynthesis*; D007515:Islets of Langerhans / Q000378:metabolism; D008297:Male; D008770:Methylnitrosourea / Q000494:pharmacology*; D051379:Mice; D008815:Mice, Inbred Strains; D009536:Niacinamide / Q000494:pharmacology; D009607:Nitrosourea Compounds / Q000494:pharmacology*; D011384:Proinsulin / Q000096:biosynthesis; D011506:Proteins / Q000378:metabolism; D013311:Streptozocin / Q000494:pharmacology*
D007328:Insulin; D009607:Nitrosourea Compounds; D011506:Proteins; D009536:Niacinamide; D013311:Streptozocin; D008770:Methylnitrosourea; D000496:Alloxan; D011384:Proinsulin