[Conformation properties and pharmacological activity of adrenergic catecholamines].
In this study, the authors propose a comparison between conformational properties and pharmacological activity of a series of adrenergic phenethylamines; in particular they conclude that if the alpha adrenergic compounds adopt a gauche conformation, beta adrenergics prefer a trans form.
D002395:Catecholamines; D008968:Molecular Conformation; D010627:Phenethylamines; D013329:Structure-Activity Relationship; D013566:Sympathomimetics
D002395:Catecholamines; D010627:Phenethylamines; D013566:Sympathomimetics
Propriétés conformationnelles et activité pharmacologique de catécholamines adrénergiques.