Phalloidin-induced proliferation of actin filaments within rat hepatocytes. Visualisation by electron microscopy and immunofluorescence.
Confirming our previous ultrastructural and biochemical studies, the combined electron microscopy and immunofluorescence investigations show that phalloidin causes a characteristically striking increase of actin filaments within rat hepatocytes. Filaments are localized mainly at the level of special junctional complexes between contiguous cells and around bile canaliculi.
D000199:Actins / Q000378:metabolism*; D000818:Animals; D005455:Fluorescent Antibody Technique; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D009842:Oligopeptides / Q000494:pharmacology*; D010590:Phalloidine / Q000494:pharmacology*; D051381:Rats
D000199:Actins; D009842:Oligopeptides; D010590:Phalloidine