title: Porous hydrophilic polymer: good and bad news in the orthopedic application of cruciate ligament substitution.
abstract: In the configuration used, the Hydron sponge did not enhance the ingrowth of bone into the Dacron for prosthesis anchorage. In fact, the presence of the Hydron seemed to retard such ingrowth, even though there was bony incorporation of portions of the Hydron polymer. Fixation was more rigid when Dacron was implanted bare. Hydron sponge does not appear to remain intact within a joint. It would not seem suitable for intra-articular protection of a prosthesis or local delivery of antibiotics here. We did not search further for the polymer in the regional lymph nodes. Hydron sponge is capable of eleciting an unusual phenomenon of woven bone formation. This is "good news" for its potential, but realization of such potential will certainly require additional study. Double and triple interval fluorochrome labelling would be especially helpful in further studying the localization and rate of this bone formation.
mesh_terms: D000179:Acrylates; D000818:Animals; D004285:Dogs; D007719:Knee Joint / Q000187:drug effects / Q000601:surgery; D008023:Ligaments, Articular / Q000601:surgery*; D008689:Methacrylates / Q000494:pharmacology; D011093:Polyethylene Terephthalates; D019736:Prostheses and Implants; D013499:Surface Properties; D014867:Water
chemical_list: D000179:Acrylates; D008689:Methacrylates; D011093:Polyethylene Terephthalates; D014867:Water