[Effect of phenoxybenzamine, propranolol and guanethidine after repeated administration on nutritional blood flow in rats].
In anesthetized rats, after i.p. treatment during 4 days: phenoxybenzamine and guanethidine were hypotensive and increased nutritional blood flow in squeletal muscles; propranolol had a poor hypotensive effect and decreased nutritional circulation in heart, skin and intestine.
D000818:Animals; D001783:Blood Flow Velocity; D001794:Blood Pressure / Q000187:drug effects; D002200:Capillary Resistance / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D003326:Coronary Circulation / Q000187:drug effects; D006145:Guanethidine / Q000494:pharmacology*; D007422:Intestines / Q000098:blood supply; D008433:Mathematics; D009132:Muscles / Q000098:blood supply; D010643:Phenoxybenzamine / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology*; D051381:Rats; D012867:Skin / Q000098:blood supply
D010643:Phenoxybenzamine; D011433:Propranolol; D006145:Guanethidine
Action de la phénoxybenzamine, du propranolol et de la guanéthidine après administration répétée sur les débits nutritionnels chez le rat