Inhibition of Mg, Ca-ATPase from E. coli by ruthenium red.
The membrane-bound, solubilized, and trypsin-treated forms of Mg, Ca-ATPase from E. coli are inhibited by ruthenium red [RR]. The inhibition is noncompetitive and is reduced at higher substrate concentrations. n-Butanol-extracted ATPase is not inhibited by ruthenium red and is not activated by KCl.
D000251:Adenosine Triphosphatases; D000440:Butanols; D002118:Calcium; D004791:Enzyme Inhibitors; D004926:Escherichia coli / Q000201:enzymology; D008274:Magnesium; D012428:Ruthenium / Q000494:pharmacology*; D012430:Ruthenium Red / Q000494:pharmacology*; D014357:Trypsin
D000440:Butanols; D004791:Enzyme Inhibitors; D012430:Ruthenium Red; D012428:Ruthenium; D014357:Trypsin; D000251:Adenosine Triphosphatases; D008274:Magnesium; D002118:Calcium