title: Histophysiological studies of prostaglandin F2alpha on isolated organs. I. Effect of prostaglandin F2alpha on the heart.
abstract: The physiological and histochemical effects of PGF2alpha on isolated rabbit hearts were examined. The results showed a positive inotropic effect. The coronary flow increased. From the histochemical studies, adenosine triphosphatase (ATP-ase) and succinic dehydrogenase activities were increased while that of alkaline phosphatase was decreased. Glycogen granules were depleted. These findings were discussed on a histophysiological basis.
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D003326:Coronary Circulation / Q000187:drug effects; D005260:Female; D006003:Glycogen / Q000378:metabolism; D006321:Heart / Q000187:drug effects*; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects; D009206:Myocardium / Q000201:enzymology; D011460:Prostaglandins F / Q000494:pharmacology*; D011817:Rabbits; D013385:Succinate Dehydrogenase / Q000378:metabolism
chemical_list: D011460:Prostaglandins F; D006003:Glycogen; D013385:Succinate Dehydrogenase; D000469:Alkaline Phosphatase; D000251:Adenosine Triphosphatases