[On the carcinogenic action of N-nitroso compounds. 6th communication: methoxymethyl-methylnitrosamine, 1-(methoxy)-ethyl-ethylnitrosamine, methoxymethyl-ethylnitrosamine, 1-(methoxy)-ethyl-methylnitrosamine, and N-nitrosooxazolidine (author's transl)].
The compounds mentioned in the title were tested for carcinogenicity in rats. All compounds proved to be carcinogens which showed interesting differences above all in the organotropy of action and in the induction periods of tumors.
D000818:Animals; D001711:Biotransformation; D002273:Carcinogens; D005260:Female; D007928:Lethal Dose 50; D008113:Liver Neoplasms / Q000139:chemically induced; D008175:Lung Neoplasms / Q000139:chemically induced; D008297:Male; D009374:Neoplasms, Experimental / Q000139:chemically induced*; D009602:Nitrosamines / Q000633:toxicity*; D009603:Nitroso Compounds / Q000633:toxicity*; D009928:Organ Specificity; D010080:Oxazoles / Q000633:toxicity*; D051381:Rats
D002273:Carcinogens; D009602:Nitrosamines; D009603:Nitroso Compounds; D010080:Oxazoles
Zur carcinogenen Wirkung von N-Nitroso-Verbindungen. 6. Mitteilung: Methoxymethyl-methylnitrosamin, 1-(Methoxy)-äthyl-äthylnitrosamin, Methoxymethyl-äthylnitrosamin, 1-(Methoxy)-äthyl-methylnitrosamin und N-Nitrosooxazlidin