title: [Reversibility of structural changes in the chromatin of peripheral blood lymphocyte interphase nuclei in patients suffering Down's disease under influence of serum from healthy subjects].
abstract: By using fluorescent microscopy and acridine orange staining it has been shown in the studies on a short-term human cell culture that the cellular chromatin DNA melting curve at the temperature range of 78--85 degrees C depends on changing conditions of the environment, i. e. on the composition of the blood serum.
mesh_terms: D000328:Adult; D055598:Chemical Phenomena; D002621:Chemistry; D002843:Chromatin; D004247:DNA; D004314:Down Syndrome / Q000235:genetics / Q000628:therapy*; D006358:Hot Temperature; D006801:Humans; D007116:Immunization, Passive; D066298:In Vitro Techniques
chemical_list: D002843:Chromatin; D004247:DNA
vernacular_title: Obratimost' pod vliianiem syvorotki zdorovog cheloveka strukturnykh izmeneniĭ khromatina interfaznykh iader limfotsitov perifericheskoĭ krovi u bol'nykh, stradaiushchikh bolezn'iu Dauna