[Anti-androgen treatment of acne (author's transl)].
A group of women suffering from acne vulgaris or post-pubertal acne was selected for a trial of anti-androgen treatment on the basis of suspected concomitant endocrine disorder from the case history. A satisfactory response to anti-androgen treatment was obtained in 80% of these subjects. The serum testosterone levels, which were slightly elevated or within the normal range prior to therapy, decreased significantly in response to anti-androgen treatment with an oral contraceptive of the combined type containing cyproterone acetate and ethinyl oestradiol. The highest rate of response was observed in patients with post-pubertal acne resistant to conventional therapy.
D000152:Acne Vulgaris / Q000097:blood / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D000726:Androgen Antagonists / Q000494:pharmacology / Q000627:therapeutic use*; D003270:Contraceptive Agents / Q000627:therapeutic use; D003534:Cyproterone / Q000627:therapeutic use; D004997:Ethinyl Estradiol / Q000627:therapeutic use; D005260:Female; D006801:Humans; D011627:Puberty; D013739:Testosterone / Q000097:blood
D000726:Androgen Antagonists; D003270:Contraceptive Agents; D013739:Testosterone; D004997:Ethinyl Estradiol; D003534:Cyproterone
Die Anwendung von Antiandrogenen in der Behandlung der Akne.