[Kinetics of cell proliferation in normal epidermis before and after application of 1 per cent vitamin A-acid solution (author's transl)].
A 1 per cent Vitamin A-acid solution was applied externally for 2 weeks on normal epidermis. The result was an acute dermatitis, characterized by hyperproliferation and shortened phases of cell cycle. There was no increase in the proliferative activity of lymphoid cells in the moderate dermal infiltrate.
D000287:Administration, Topical; D002250:Carbon Radioisotopes; D002455:Cell Division / Q000187:drug effects; D003875:Drug Eruptions; D006801:Humans; D007700:Kinetics; D012867:Skin / Q000187:drug effects*; D013997:Time Factors; D014212:Tretinoin / Q000008:administration & dosage / Q000009:adverse effects*; D014801:Vitamin A / Q000031:analogs & derivatives*
D002250:Carbon Radioisotopes; D014801:Vitamin A; D014212:Tretinoin
Die Proliferationskinetik normaler Epidermis vor und nach äusserlicher Anwendung einer 1 per cent igen Vitamin A-Säure-Lösung