title: [Spectinomycin.  Indications and undesirable effects].
abstract: Modern chemotherapy postulates highly active drugs without unwanted side effects.  In the treatment of gonorrhea spectinomycin meets even the strictest requirements: maximal obtainable cure rates, no masking of concomitant syphilitic infections, and excellent tolerance.  In animal experiments no sensitizing effect of spectinomycin was found even when maximation procedures were applied.  Anaphylactoid activity of spectinomycin is low, as has been documented by personal investigational series.
mesh_terms: D000707:Anaphylaxis / Q000209:etiology; D001419:Bacteria / Q000187:drug effects; D002626:Chemistry, Pharmaceutical; D004342:Drug Hypersensitivity; D004352:Drug Resistance, Microbial; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D009344:Neisseria gonorrhoeae / Q000187:drug effects; D000198:Spectinomycin / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D013587:Syphilis / Q000175:diagnosis
chemical_list: D000198:Spectinomycin
vernacular_title: Spectinomycin.  Indikationen und unerwünschte Wirkungen