title: An apparent connection between histidine, recombination, and repair in Neurospora.
abstract: Two mutants of Neurospora crassa, uvs-3 and mei-3, share four properties--UV sensitivity, inhibition by histidine, meiotic blockage when homozygous, and increased duplication instability (due to mitotic crossing over, to deletions or to both). The present paper shows that a third nonallelic mutant, uvs-6, exhibits the same four properties.--Also, the instability of duplications in the absence of any UV-sensitive mutant is increased by the presence of histidine in the growth medium.
mesh_terms: D004260:DNA Repair; D006639:Histidine / Q000235:genetics*; D009154:Mutation; D009491:Neurospora / Q000235:genetics*; D009492:Neurospora crassa / Q000235:genetics* / Q000528:radiation effects; D011995:Recombination, Genetic; D014466:Ultraviolet Rays
chemical_list: D006639:Histidine