The effectiveness of topical antibacterials in acne: a double-blind clinical study.
In a double-blind study, three groups of patients with mild to moderate acne were treated for eight weeks with topical acne creams containing the antibacterials triclosan or triclosan plus propylene phenoxetol. The formula without antibacterials served as the control. Total-face lesion counts, evaluation of the overall degree of inflammation of the lesions, and patient self-assessment showed the added efficacy of the antibacterials when incorporated into the control.
D000152:Acne Vulgaris / Q000188:drug therapy*; D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005026:Ethylene Glycols / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009824:Ointments; D014260:Triclosan / Q000008:administration & dosage / Q000627:therapeutic use
D000891:Anti-Infective Agents, Local; D005026:Ethylene Glycols; D009824:Ointments; D014260:Triclosan; C016697:propylene phenoxetol