title: The reaction of the vascular pattern of the hypertrophied myocardium to increased cardiac volume load. A microangiographical study.
abstract: Myocardial stereo-microangiography was performed on 30 rats after swimming exercise for one or two periods with and without a previous operation for production of aortic stenosis. In 8 rats with aortic stenosis no swimming exercise followed, and 10 more rats served as normal controls. Swimming exercise resulted in a higher degree of cardiac hypertrophy than aortic stenosis. Both types of cardiac hypertrophy resulted in vascular adaptive reactions in the myocardium. The adaptive reaction to swimming exercise was found to be persistent, at least to some extent, and to be of use if the exercise was resumed. The adaptive alterations in aortic stenosis were further modified by a superimposed period of exercise, although the nutritive capillary vasculature only showed a slight and focal increase in density.
mesh_terms: D000818:Animals; D001024:Aortic Valve Stenosis / Q000473:pathology; D002196:Capillaries / Q000000981:diagnostic imaging / Q000473:pathology; D002306:Cardiac Volume; D006332:Cardiomegaly / Q000473:pathology*; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000473:pathology*; D009206:Myocardium / Q000473:pathology*; D005082:Physical Exertion; D051381:Rats; D013550:Swimming