Fibrous long spacing type collagen fibrils in the glomeruli of experimental amyloidosis in rabbit.
Fibrous long spacing type collagen fibrils were observed in the glomeruli of experimental amyloidosis induced by either injections of casein or prolonged sensitization of Arthus type tissue antigens in the rabbit. These fibrous long spacing type fibrils were admixed with amyloid fibrils which accumulated both in nodular and diffuse deposition, but they were observed also in irregularly thickened capillary basement membranes and mesangial areas, where amyloid did not deposit. The periodicity of these fibrous long spacing fibrils was approximately 1200 , and nine symmetrical intraperiodic bands were obviously discerned within each period.
D000682:Amyloid; D000686:Amyloidosis / Q000139:chemically induced / Q000473:pathology*; D000818:Animals; D000941:Antigens; D001183:Arthus Reaction; D001485:Basement Membrane / Q000648:ultrastructure; D002364:Caseins; D003094:Collagen; D007674:Kidney Diseases / Q000473:pathology*; D007678:Kidney Glomerulus / Q000473:pathology / Q000648:ultrastructure*; D008854:Microscopy, Electron; D011817:Rabbits
D000682:Amyloid; D000941:Antigens; D002364:Caseins; D003094:Collagen