[Modifications by BCG of the mortality of the irradiated mouse].
Freeze-dried Bacillus Calmette Guerin (B.C.G.) of Institut Pasteur was given by intravenous route to mice at 1,2 and 4 mg/kg before and after gamma irradiation of animals by 1 000 rad. B.C.G. 1 mg/kg injected the day or the day after irradiation has a protective effect (mortality reduced from 77% for controls to 58% and 50% for treated mice). B.C.G. given before irradiation in single or double doses increased mortality.
D000818:Animals; D001500:BCG Vaccine; D007109:Immunity / Q000528:radiation effects; D007275:Injections, Intravenous; D008297:Male; D051379:Mice; D009163:Mycobacterium bovis / Q000276:immunology; D011833:Radiation Injuries, Experimental / Q000276:immunology*; D011837:Radiation-Protective Agents; D011838:Radiation-Sensitizing Agents; D013997:Time Factors
D001500:BCG Vaccine; D011837:Radiation-Protective Agents; D011838:Radiation-Sensitizing Agents
Modification par le B.C.G. de la mortalité de la souris irradiée