Platelet turnover in metastatic cancer and the effect of platelet aggregation inhibitors.
Patients with metastatic cancer have a permanent shortening of platelet survival and increased platelet consumption. Acetylsalicylic acid or dipyridamole in doses known to inhibit platelet aggregation, had no effect on platelet consumption.
D001241:Aspirin / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D004176:Dipyridamole / Q000494:pharmacology; D006801:Humans; D009362:Neoplasm Metastasis / Q000097:blood*; D010974:Platelet Aggregation / Q000187:drug effects*
D004176:Dipyridamole; D001241:Aspirin