[Comparative study of the insulin-secreting effects of L (+) and of D (-) sodium lactate].
Both sodium 6(+) and D(-) lactate stimulate insulin secretion from the isolated perfused rat pancreas; however the insulin secretory effect of the L(+) form is much superior to that of the D(-) form. Glucagon secretion is not modified by the two isomers.
D000818:Animals; D066298:In Vitro Techniques; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects*; D007773:Lactates / Q000494:pharmacology*; D051381:Rats; D012636:Secretory Rate / Q000187:drug effects; D013237:Stereoisomerism; D013268:Stimulation, Chemical
D007328:Insulin; D007773:Lactates
Etude comparative des effets insulino-sécréteurs du L (+) et du D (-) lactate de sodium