Evaluation of oxfendazole against natural infections of gastro-intestinal nematodes and lung-worms in calves.
The anthelmintic activity of oxfendazole (Syntex) was tested in calves at dosages of 2-5 and 5-0 mg per kg. At both dose levels, oxfendazole showed 100 per cent efficacy against adult Ostertagia ostertagi, O lyrata, O cremensis, fifth stage Ostertagia spp and adult Haemonchus spp. Against adult Cooperia oncophora, efficacy was 99.8 per cent and 100 per cent at doses of 2.5 mg per kg and 5.0 mg per kg respectively while at both dose levels 100 per cent activity was recorded against C surnabada and fourth and fifth stage Cooperia spp. One hundred per cent efficacy was obtained with both dose levels against adult and fifth stage Dictyodaulus viviaprus; against Trichuris spp, percentage efficacy was 92 and 100 per cent at doses 2.5 and 5.0 mg per kg respectively. Oxfendazole showed higher efficacy than levamisole against Ostertagia spp but against the other species encountered, both anthelmintics possessed similar efficacy. Both anthelmintics significantly increased the calves' weight gains.
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D002219:Carbamates / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D004022:Dictyocaulus Infections / Q000188:drug therapy*; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000662:veterinary*; D007978:Levamisole / Q000627:therapeutic use; D009349:Nematode Infections / Q000662:veterinary*; D010029:Ostertagiasis / Q000188:drug therapy / Q000662:veterinary; D013272:Stomach Diseases / Q000188:drug therapy / Q000662:veterinary*; D014252:Trichostrongyloidiasis / Q000188:drug therapy / Q000662:veterinary
D000871:Anthelmintics; D001562:Benzimidazoles; D002219:Carbamates; D007978:Levamisole; C011030:oxfendazole