Antitumor effect of protein-bound polysaccharide preparation, PS-K, against 3-methylcholanthrene-induced fibrosarcoma in C57BL/6 mice.
The protein-bound polysaccharide preparation, PS-K, was found to possess an antitumor effect against 3-methylcholanthrene-induced fibrosarcoma in mice which was shown to have a tumor-specific transplantation antigen. This antitumor effect seemed to be exerted through a host-mediated tumor immunity.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D001487:Basidiomycota; D005260:Female; D005354:Fibrosarcoma / Q000139:chemically induced / Q000188:drug therapy*; D006025:Glycosaminoglycans / Q000627:therapeutic use*; D008748:Methylcholanthrene; D051379:Mice; D008810:Mice, Inbred C57BL; D009374:Neoplasms, Experimental; D011509:Proteoglycans / Q000627:therapeutic use*
D000903:Antibiotics, Antineoplastic; D006025:Glycosaminoglycans; D011509:Proteoglycans; D008748:Methylcholanthrene