[Immunglobulin G-, M- and A-levels after 3 and 6 days intravenous treatment by D-penicillamin (author's transl)].
In 10 patients with lung fibrosis the serum levels of immunglobulins G, A and M were determined before and after a 3 days-treatment by D-Penicillamine (1.0 g/die i.v.) by the radialimmunodiffusion method of Mancini. There is a fall in the immunglobulins IgG and IgM, the levels of IgA are not lowered. Continuing the treatment with 2 times 1.00 g D-Penicillamine per day for 3 further days does not lower the levels of IgM and IgG further.
D000328:Adult; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D007275:Injections, Intravenous; D008297:Male; D010396:Penicillamine / Q000008:administration & dosage / Q000627:therapeutic use*; D011658:Pulmonary Fibrosis / Q000097:blood / Q000188:drug therapy
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D010396:Penicillamine
Immunoglobulin G-, M- und A-Spiegel nach 3- und 6tägiger intravenöser D-Penicillamintherapie