Improved method for measuring fibrinogen in plasma, with use of a plasmin inhibitor.
We describe a modified procedure for quantitating plasma fibrinogen by use of the thrombin-clottable protein technique. The method is accurate and requires a0out 30 min to complete. During its formation and isolation, the clot is protected from the degradative action of plasmin by an inhibitor, epsilon-aminocaproic acid.
D000614:Aminocaproates / Q000494:pharmacology; D001780:Blood Coagulation Tests; D005340:Fibrinogen / Q000032:analysis*; D005341:Fibrinolysin / Q000037:antagonists & inhibitors*; D007700:Kinetics; D013053:Spectrophotometry / Q000379:methods; D013300:Streptokinase
D000614:Aminocaproates; D005340:Fibrinogen; D013300:Streptokinase; D005341:Fibrinolysin