title: Atrial myxoma in a family.
abstract: A family is described in which the mother and three of seven children had atrial myxoma. The mother had biatrial myxoma; surgical treatment resulted in massive intraoperative embolization and death. Surgery was sucessful in two sons with left atrial myxoma and systemic arterial embolization. A third son had calcified right atrial myxoma with destruction of the tricuspid valve and episodes of syncope and pulmonary embolism; surgery including valve replacement, was successful. The mother's father and a brother had died suddenly without a definite diagnosis. The family data are consistent with dominant transmission. The possibility of finding affected relatives should be borne in mind when studying patients with atrial myxoma.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000790:Angiocardiography; D006328:Cardiac Catheterization; D006332:Cardiomegaly / Q000000981:diagnostic imaging; D004200:Diseases in Twins; D004452:Echocardiography; D004562:Electrocardiography; D004617:Embolism / Q000601:surgery; D005260:Female; D006325:Heart Atria / Q000601:surgery*; D006338:Heart Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics* / Q000601:surgery; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000000981:diagnostic imaging / Q000235:genetics* / Q000601:surgery; D010375:Pedigree