[Characteristics of guinea pig anti-bovine parathormone antiserum used in radioimmunologic determination of human parathormone].
The cross-reaction for hPTH radioimmunoassay and the multiple forms of hPTH circulating, pose several problems in interpreting results. This communication reports a sensitive radioimmunoassay for hPTH utilising a guineapig antiserum which is reactive with the amino-terminal region retaining biological activity, and which cross-reacts completely with hPTH, indicating levels of hPTH expressed as bovine PTH equivalent that would be correct.
D000818:Animals; D002417:Cattle; D003429:Cross Reactions; D006168:Guinea Pigs / Q000276:immunology; D006801:Humans; D006961:Hyperparathyroidism / Q000097:blood; D010281:Parathyroid Hormone / Q000097:blood / Q000276:immunology*; D011863:Radioimmunoassay / Q000379:methods*
D010281:Parathyroid Hormone
Etude des caractéristiques d'un antisérum de cobaye antiparathormone bovine utilisé dans une technique de dosage radioimmunologique de la parathormone humaine