title: Thymidylate synthetase - a target enzyme in cancer chemotherapy.
mesh_terms: D000818:Animals; D001667:Binding, Competitive; D003545:Cysteine / Q000378:metabolism; D004273:DNA, Neoplasm / Q000096:biosynthesis; D003856:Deoxyuracil Nucleotides / Q000378:metabolism / Q000494:pharmacology*; D005260:Female; D005467:Floxuridine / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007460:Iodoacetamide / Q000031:analogs & derivatives; D007700:Kinetics; D008297:Male; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D008956:Models, Chemical; D009369:Neoplasms / Q000188:drug therapy / Q000201:enzymology* / Q000378:metabolism; D013763:Tetrahydrofolates / Q000378:metabolism; D013873:Thionucleotides / Q000378:metabolism / Q000494:pharmacology; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013942:Thymine Nucleotides / Q000378:metabolism / Q000494:pharmacology
chemical_list: D004273:DNA, Neoplasm; D003856:Deoxyuracil Nucleotides; D013763:Tetrahydrofolates; D013873:Thionucleotides; D013942:Thymine Nucleotides; D005467:Floxuridine; D008780:Methyltransferases; D013940:Thymidylate Synthase; D003545:Cysteine; D007460:Iodoacetamide