Changes in the activities of blood and tissue adenosinetriphosphatase and lactate dehydrogenase after exposure to 60Co gamma-rays in association with some drug treatments.
Experiments in rats exposed to a moderate dose of 60Co gamma-radiation and treated with either cystamine, AET, complamin or alpha-methyldopa suggested that the efficiency of a radioprotective drug might be related to its ability to maintain low levels of ATP-ase activity in blood and tissues after irradiation.
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D003037:Cobalt Radioisotopes; D003538:Cystamine / Q000494:pharmacology*; D005720:Gamma Rays; D007413:Intestinal Mucosa / Q000201:enzymology; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D008750:Methyldopa / Q000494:pharmacology*; D011830:Radiation Effects; D051381:Rats; D013154:Spleen / Q000201:enzymology; D013806:Theophylline / Q000031:analogs & derivatives*; D014971:Xanthinol Niacinate / Q000494:pharmacology*; D000338:beta-Aminoethyl Isothiourea / Q000494:pharmacology*
D003037:Cobalt Radioisotopes; D000338:beta-Aminoethyl Isothiourea; D008750:Methyldopa; D014971:Xanthinol Niacinate; D013806:Theophylline; D007770:L-Lactate Dehydrogenase; D000251:Adenosine Triphosphatases; D003538:Cystamine