title: Current angiographic approach to diagnosis and therapy of acute gastrointestinal bleeding.
abstract: The author's current angiographic approach to the diagnosis and therapy of acute gastrointestinal (GI) bleeding is summarized and discussed. It is based on the authors' experience with diagnostic studies in more than 300 acute GI bleeders and the use of various angiotherapeutic techniques in 138 of them as well as the experience of others. A "moderately aggressive angiographic approach" is advocated for the diagnosis of acute GI bleeding in most patients with angiography used as needed after emergency endoscopy and preliminary medical therapy. Vasoconstrictive angiotherapy with selective intraarterial use of vasopressin is partially giving way to low dose, intravenous infusion of vasopressin and, where possible, to direct vascular occlusion. Selective transcatheter embolic occlusion of bleeding vessels is in indicated cases an accepted method for controlling arterial bleeding. Medical gelatin (Gelfoam) is the current authors' embolization material of choice. Selective variceal occlusion offers promising means for management of bleeding from gastroesophageal varices. Its possible combination with transcatheter intrahepatic portosystemic shunting might also provide non-surgical relief of portal hypertension.
mesh_terms: D000208:Acute Disease; D004932:Esophageal and Gastric Varices / Q000150:complications; D005756:Gastritis / Q000150:complications; D006471:Gastrointestinal Hemorrhage / Q000000981:diagnostic imaging* / Q000209:etiology; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use; D006489:Hemostatic Techniques; D006801:Humans; D007082:Ileum; D010438:Peptic Ulcer Hemorrhage / Q000628:therapy; D010439:Peptic Ulcer Perforation / Q000150:complications; D011859:Radiography; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
chemical_list: D014662:Vasoconstrictor Agents