Regulation of actin-myosin interaction.
In the presence of the regulatory protein complex tropomyosin-troponin ATPase activity of vertebrate skeletal muscle actomyosin is either higher or lower than in the absence of tropomyosin-troponin. The actual behavior depends on ionic strength, Ca2+ concentration, ATP concentration (determining the amount of rigor complexes present), and the ratio between actin and myosin. This effect of the myosin-actin ratio implies that under certain conditions cooperativity in actin-myosin interaction can be seen.
D000199:Actins / Q000378:metabolism*; D000205:Actomyosin / Q000378:metabolism; D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D009218:Myosins / Q000378:metabolism*; D014335:Tropomyosin / Q000378:metabolism; D014336:Troponin / Q000378:metabolism
D000199:Actins; D014335:Tropomyosin; D014336:Troponin; D000205:Actomyosin; D000251:Adenosine Triphosphatases; D009218:Myosins; D002118:Calcium