title: Occupational dermatosis due to a soil fumigant.
abstract: D-D mixture is a preplant soil fumigant. It contains dichloropropanes and dichloropropenes, epichlorohydrin and is known as a primary irritant. Three cases of untoward reaction to D-D are reported. By patch testing, the existence of a contact allergic sensitivity to D-D could be proved in one patient. The other two cases reacted negatively; they were probably of a primary irritant origin. Patch tests with compounds related to D-D suggest that the cause of contact allergy must be sought in the propene(s) fraction of D-D. In future cases of untoward reactions to D-D, patch testing appears to be necessary in order to differentiate between a contact allergic and a primary irritant reaction.
mesh_terms: D000969:Antinematodal Agents / Q000009:adverse effects; D002728:Chlorohydrins / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000139:chemically induced* / Q000175:diagnosis; D004811:Epichlorohydrin / Q000009:adverse effects*; D005651:Fumigation; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000009:adverse effects*; D010328:Patch Tests; D012987:Soil
chemical_list: D000969:Antinematodal Agents; D002728:Chlorohydrins; D006843:Hydrocarbons, Chlorinated; D012987:Soil; D004811:Epichlorohydrin; C007792:Fumigant 93