'Sezary-like' cells in malignant and non-malignant diseases.
Lymphocyte-like distinctive cells with cerebriform and serpentiform nuclei, as described in 'Sézary syndrome' were detected in the peripheral blood of two patients, one with plasma-cell leukemia and one with bacterial sepsis. These observations suggest that 'Sézary cells' are not strictly specific, neither for a neoplastic nor for a nonneoplastic disease, but rather representing a reactive form of lymphocytes to different stimuli.
D002467:Cell Nucleus / Q000648:ultrastructure; D003873:Dermatitis, Exfoliative / Q000473:pathology; D005260:Female; D006801:Humans; D007952:Leukemia, Plasma Cell / Q000648:ultrastructure*; D008206:Lymphatic Diseases / Q000473:pathology*; D008214:Lymphocytes / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged; D011549:Pseudomonas; D018805:Sepsis / Q000473:pathology*; D013577:Syndrome