title: [Medico-genetic study of the population of Uzbekistan. IV. Medico-genetic description of the population of 4 villages of the Urgut district of the Samarkand region].
abstract: The data about the incidence of hereditary diseases and those with genetic predispositions which received after subtotal medico-genetical examination of the inhabitants of 4 villages in the Urgut district of the Samarkand province are presented. 848 inhabitants (348 adults and 464 children aged 7--16 years) are examined. The nosological profile of the morbidity and spectrum of the Mendelian diseases in the population is evaluated. The integrative estimate of load of the detrimental (non-lethal) genes is about 0.166 per individual.
mesh_terms: D000328:Adult; D000367:Age Factors; D002648:Child; D000013:Congenital Abnormalities / Q000453:epidemiology / Q000235:genetics; D005260:Female; D005787:Gene Frequency; D030342:Genetic Diseases, Inborn / Q000453:epidemiology* / Q000235:genetics; D005828:Genetics, Population; D005843:Geography; D006801:Humans; D008297:Male; D014610:Uzbekistan
vernacular_title: Mediko-geneticheskoe izuchenie naseleniia Uzbekistana. Soobshchenie IV. Mediko-geneticheskoe opisanie naseleniia chetyrekh kishlakov Urgutskogo raiona Samarkandskoĭ oblasti.