Reinstitution of gold therapy in rheumatoid arthritis after mucocutaneous reactions.
Gold therapy was successfully reinstituted in 28 of 30 patients with rheumatoid arthritis who had previously developed toxic, mucocutaneous reactions. At least six weeks after the reactions had completely cleared, patients were given 1 to 10 mg of gold sodium thiomalate (Myochrysine). This dose was increased every two to four weeks. An initial dose of 1 or 2 mg, with an interval of at least three weeks between injections, increasing not more than5 mg at each injection, is recommended.
D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004334:Drug Administration Schedule; D003875:Drug Eruptions / Q000276:immunology / Q000517:prevention & control*; D005260:Female; D006052:Gold Sodium Thiomalate / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D013280:Stomatitis / Q000139:chemically induced
D006052:Gold Sodium Thiomalate