[Heart noradrenaline and dopamine during acute poisoning of rat by an anticholinesterasic pesticide: parathion].
Noradrenaline level in rat heart decreased after intoxication by parathion. The pharmacological investigations appeared to prove that this decrease results from the storage of acetylcholine, which provoked likewise a slowing of the cardiac rythm. The role of atropine is discussed.
D000109:Acetylcholine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002219:Carbamates / Q000494:pharmacology; D003975:Diazepam / Q000494:pharmacology; D004298:Dopamine / Q000032:analysis*; D005260:Female; D006321:Heart / Q000187:drug effects*; D006339:Heart Rate; D009206:Myocardium / Q000032:analysis; D009638:Norepinephrine / Q000032:analysis*; D010278:Parathion / Q000494:pharmacology*; D051381:Rats; D012640:Seizures / Q000517:prevention & control
D002219:Carbamates; D010278:Parathion; D001285:Atropine; D000109:Acetylcholine; D003975:Diazepam; D004298:Dopamine; D009638:Norepinephrine
La noradrénaline et la dopamine cardiaques lors de l'intoxication aiguë du rat par un pesticide anticholinestérasique: le parathion