[Report on two cases of bullous manifestations, one of which being a pemphigus, induced by penicillamine (author's transl)].
Cutaneous bullous disease may be induced by D-penicillamin. We have briefly reviewed what was then possible: bullosa epidermolysis, pemphigus, bullous toxiderma. We have had the opportunity to observe twice this phenomenon. In one case, as already mentioned about fifteen times in the literature, it was a pemphigus. Its clinical, histological and immunological features are mentioned, and its good prognosis confirmed. The other case gives matter to discussion about toxic pre-pemphigus.
D003875:Drug Eruptions / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010392:Pemphigus / Q000139:chemically induced* / Q000473:pathology; D010396:Penicillamine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000473:pathology
D010396:Penicillamine
A propos de deux cas d'accidents bulleux, dont un cas de pemphigus, dus à la pénicillamine.