Cavitating lung nodules and pneumothorax in children with metastatic Wilms' tumor.
Lung metastases evolved into large thin-walled cysts in two children with Wilms' tumor. Histologic examination of one lesion suggested that invasion of a small bronchus or bronchiole, leading to ball-valve obstruction, was responsible. One patient also experienced recurrent pneumothorax, probably on the same basis. The formation of thin-walled cysts has not previously been observed with metastatic Wilms' tumor. Pneumothorax is a rare complication of metastatic Wilms' tumor.
D001984:Bronchial Neoplasms / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D009336:Necrosis; D009362:Neoplasm Metastasis; D011030:Pneumothorax / Q000150:complications / Q000000981:diagnostic imaging*; D011859:Radiography; D009396:Wilms Tumor / Q000473:pathology*