title: [Comparative characteristics of antigenic peculiarities and several other properties of stable long-term cultures of salmonella L-forms].
abstract: Enzymatic properties, sensitivity to antibiotics and peculiarities of the antigenic structure of stable L-forms of S. paratyphi B (L-115), S. typhimurium (L-71a-16) and S. typhi (L-5761) were studied. In difference from the initial strains, the L-form under study possessed a high penicillin and ampicillin sensitivity, and also a marked sensitivity to polymyxin and detergents; this characterized them as L-forms of protoplastic type. All the L-variants differed considerably by the enzymatic properties from the initial strains, and, in the majority of cases, retained the antigenic components and the species-specificity characteristic of the initial parental cultures. Despite the loss of the cell wall the synthesis of O-antigen in the L-forms under study was undisturbed. The 6-forms contained an antigenic component not found in the initial cultures and apparently causing the neutralizing activity of the L-antiser.
mesh_terms: D000372:Agglutination Tests; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000942:Antigens, Bacterial; D003902:Detergents / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007740:L Forms / Q000276:immunology*; D011113:Polymyxins / Q000494:pharmacology; D012475:Salmonella / Q000187:drug effects / Q000201:enzymology / Q000276:immunology*; D012484:Salmonella paratyphi B / Q000276:immunology; D012485:Salmonella typhi / Q000276:immunology; D012486:Salmonella typhimurium / Q000276:immunology; D013045:Species Specificity
chemical_list: D000900:Anti-Bacterial Agents; D000942:Antigens, Bacterial; D003902:Detergents; D011113:Polymyxins
vernacular_title: Sravnitel'naia kharakteristika antigennykh osobennosteĭ i nekotorykh drugikh svoĭstv stabil'nykh dlitel'no kul'tiviruemykh L-form sal'monell