[Ultrastructure of the blood platelets in the newborn infant and in the young mongolian child. Study of 13 cases].
Blood platelets from infant and new born mongolians were examined and compared taking into consideration existing or non existing haematologic anomalies, such as transitory leucoblastosis with or without hyperthrombocytosis and acute leucosis without thrombopenia. These abnormalities were correlated with the analysis of control samples from haematologically normal new-born and premature children as well as samples from adult mongolian, patients with other chromosomal alterations (13-15, phi) and new-born or adults with thrombocytosis. The presence of dysmorphic platelets could be observed in variable degrees and numbers in all the mongolian samples. The characters of the morphologic abnormalities, constantly observed with variations due to pathological causes, denote either metabolic or structural thrombopathy.
D000208:Acute Disease; D000328:Adult; D001791:Blood Platelet Disorders / Q000209:etiology; D001792:Blood Platelets / Q000378:metabolism / Q000648:ultrastructure*; D002648:Child; D002901:Chromosomes, Human, 13-15; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004314:Down Syndrome / Q000097:blood* / Q000150:complications; D006003:Glycogen / Q000378:metabolism; D006801:Humans; D002479:Inclusion Bodies / Q000378:metabolism; D007223:Infant; D007231:Infant, Newborn; D007955:Leukemoid Reaction / Q000150:complications; D007964:Leukocytosis / Q000150:complications; D050356:Lipid Metabolism; D008218:Lymphocytosis / Q000150:complications; D008533:Megakaryocytes / Q000648:ultrastructure; D013922:Thrombocytosis / Q000150:complications; D014617:Vacuoles / Q000648:ultrastructure
D006003:Glycogen
Ultrastructure des plaquettes sanguines chez le nouveau-né et le jeune enfant mongolien. Etude de 13 cas