Opposite effects of vasotocin injected intrapituitarly and intraventricularly on corticotropin release in mice.
A single injection of 10 pg synthetic arginine vasotocin into the pituitary significantly potentiated adrenal hypertrophy produced in male mice by unilateral adrenalectomy, whereas the same concentration injected into the 3rd ventricle produced adrenal atrophy.
D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000818:Animals; D007276:Injections, Intraventricular; D008297:Male; D051379:Mice; D009929:Organ Size; D010902:Pituitary Gland / Q000187:drug effects*; D010903:Pituitary Gland, Anterior / Q000187:drug effects* / Q000378:metabolism; D014668:Vasotocin / Q000008:administration & dosage / Q000494:pharmacology*
D000324:Adrenocorticotropic Hormone; D014668:Vasotocin