title: Demonstration of intracellular growth of gonococci in human phagocytes using spectinomycin to kill extracellular organisms.
abstract: The use of spectinomycin to kill extracellular bacterial in phagocytosis tests with gonococci and human polymorphonuclear phagocytes allowed the demonstration of a greater degree of intracellular survival and growth than in previous tests using penicillin.
mesh_terms: D006801:Humans; D009344:Neisseria gonorrhoeae / Q000187:drug effects / Q000254:growth & development*; D009504:Neutrophils / Q000382:microbiology*; D010587:Phagocytosis; D000198:Spectinomycin / Q000494:pharmacology*
chemical_list: D000198:Spectinomycin