title: [Ultrastructural study of the different zones of the rat liver acinus after portacaval anastomosis].
abstract: Liver atrophy is a main feature in rats with a porto caval shunt. Histological studies revealed small size hepatocytes. Ultrastructural differences between periportal and centrolobular zones were noticed, in particular, the dilatation of the nuclear envelope and of the rough endoplasmic reticulum which appeared dilated, desorganized and sometimes without ribosomes, was more pronounced in the periportal zone. Hepatocytes of this zone might be more sensitive to the decrease of O2 and/or hepatotrophic factors.
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D008099:Liver / Q000166:cytology / Q000648:ultrastructure*; D008297:Male; D008930:Mitochondria, Liver / Q000648:ultrastructure; D011167:Portacaval Shunt, Surgical / Q000009:adverse effects; D051381:Rats
vernacular_title: Etude ultrastructurale des différentes zones de l'acinus hépatique de rat après anastomose porto-cave.