title: [Experience in the use of competitive binding of hormones with proteins for the determination of non-metabolized glucocorticoids in the blood and urine in some pituitary-adrenal diseases].
abstract: A method of competitive protein-binding analysis was applied to the study of nonmetabolized glucocorticoids (NMG) in the plasma and urine of healthy persons and those suffering from hyper- and hypocorticism.  NMG determination by this method reflected adequately the funcitonal condition of the adrenal cortex under normal conditions and in hypophyseo-adrenal diseases, including tests with ACTH and dexametazan, and coordinated with the results obtained by standard chemical methods.
mesh_terms: D000309:Adrenal Insufficiency / Q000175:diagnosis / Q000378:metabolism*; D000324:Adrenocorticotropic Hormone; D001667:Binding, Competitive; D003480:Cushing Syndrome / Q000175:diagnosis / Q000378:metabolism*; D003907:Dexamethasone; D005938:Glucocorticoids / Q000097:blood / Q000378:metabolism* / Q000652:urine; D006801:Humans; D010912:Pituitary-Adrenal Function Tests; D010913:Pituitary-Adrenal System; D011485:Protein Binding
chemical_list: D005938:Glucocorticoids; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone
vernacular_title: Opyt primeneniia metoda konkurentnogo sviazyvaniia gormonov belkami dlia opredeleniia nemetabolizirovannykh gliukokortikoidov v krovi i moche pri nekotorykh gipofizarno-nadpochechnikovykh zabolevaniiakh