[Morphological and cytochemical characteristics of human cells transformed and made malignant by Rous and polyoma viruses].
In cells of human embryo skin--muscle tissue transformed by the Rouse sarcoma virus (23rd cell line) and polyoma virus (P-2 cell line), the mitotic activity was 48 0/00 for 23rd line, 51 0/00 for P-2 line as against 28 0/00 in the control cells. The transformed cells possessed greater amounts of RNA and DNA and protein--bound SH-groups, different forms of glycogen deposits, as well as higher acid phosphatase enzyme activities; there was practically no difference in acid mucopolysaccharide content or NAD-H2-diaphorase and succinate dehydrogenase activities.
D000135:Acid Phosphatase / Q000032:analysis; D001358:Avian Sarcoma Viruses; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured / Q000032:analysis / Q000201:enzymology; D002875:Chromosomes; D004247:DNA / Q000032:analysis; D004273:DNA, Neoplasm / Q000032:analysis; D008058:Dihydrolipoamide Dehydrogenase / Q000032:analysis; D006003:Glycogen / Q000032:analysis; D006025:Glycosaminoglycans / Q000032:analysis; D006801:Humans; D008938:Mitosis; D011120:Polyomavirus; D011123:Polyploidy; D012313:RNA / Q000032:analysis; D012334:RNA, Neoplasm / Q000032:analysis; D013385:Succinate Dehydrogenase / Q000032:analysis; D013438:Sulfhydryl Compounds / Q000032:analysis
D004273:DNA, Neoplasm; D006025:Glycosaminoglycans; D012334:RNA, Neoplasm; D013438:Sulfhydryl Compounds; D012313:RNA; D006003:Glycogen; D004247:DNA; D013385:Succinate Dehydrogenase; D008058:Dihydrolipoamide Dehydrogenase; D000135:Acid Phosphatase
Morfologicheskaia i tsitokhimicheskaia kharakteristika kletok cheloveka, transformirovannykh i malignizirovannykh virusami Rausa i poliomy