[Ultrastructural characteristics of experimental tumors of the intestine].
Tumors of the rat large intestine induced by subcutaneous injection of 1,2-dimethylhydrazine were studied by the method of electron microscopy. Adenocarcinomas retained histiotypical differentiation and at the same time consisted mostly of cells with a low rate of differentiation. Just on the contrary, in mucous and signet-ring cell carcinomas the picture of an advanced cell differentiation was observed in a complete loss of organogeny. The greatest malignancy of neoplasms (signet-ring carcinoma), which cells are characterized by a high degree of cytological differentiation, is a manifestation of independence of tumor progression signs.
D000230:Adenocarcinoma / Q000473:pathology*; D002288:Adenocarcinoma, Mucinous / Q000473:pathology*; D000818:Animals; D002454:Cell Differentiation; D007414:Intestinal Neoplasms / Q000473:pathology*; D007420:Intestine, Large / Q000648:ultrastructure*; D008297:Male; D009374:Neoplasms, Experimental / Q000473:pathology*; D051381:Rats
Ul'trastrukturnaia kharakteristika éksperimental'nykh opukholeĭ kishechnika