Neutrophil functions in acne conglobata.
Chemotaxis, random migration, phagocytosis, spontaneous and stimulated NBT reduction were evaluated in neutrophils from the peripheral blood of 8 patients with acne conglobata and were found to be normal. Only 2 patients had an increased spontaneous NBT reduction, and another exhibited a defect in neutrophil adhesiveness. On this basis, intrinsic defects of the major neutrophil functions, as evaluated in vitro, can be excluded in acne conglobata.
D000152:Acne Vulgaris / Q000097:blood / Q000276:immunology*; D000293:Adolescent; D000328:Adult; D002634:Chemotaxis, Leukocyte; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000276:immunology*; D009580:Nitroblue Tetrazolium; D010587:Phagocytosis
D009580:Nitroblue Tetrazolium