[Light and electron microscopie examination of a case of primary liver carcinoma in an infant (author's transl)].
The course of an infantial liver carcinoma is reported. Two liver biopsies and autopsy material were studied by light- and electron microscope. The histological findings and the clinical data are discussed. The first biopsy taken from the liver showed glycogen storage within the hepatic cells. It is suggested that this phenomenon is consistent with the preblastomatous stage of the liver cells. This fact is supported also by experimental way. The detection of this glycogen storage could be used as an early sign of the liver cancer in childhood, and might stress an early surgical intervention.
D001344:Autopsy; D001706:Biopsy; D006528:Carcinoma, Hepatocellular / Q000032:analysis / Q000473:pathology*; D002471:Cell Transformation, Neoplastic; D005260:Female; D006003:Glycogen / Q000032:analysis; D006801:Humans; D007223:Infant; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000032:analysis / Q000473:pathology*; D008854:Microscopy, Electron
D006003:Glycogen
Licht- und elektronenmikroskopische Untersuchungen in einem Fall von primärem Leberkarzinom im Säuglingsalter