[Enzyme histochemical studies on the macula and Goormaghtigh cells of the guinea pig kidney].
Starting from the ultrastructural differences observed between the juxtaglomerular apparatus of the rat and that--only very rarely analysed--of the guinea pig kidney, the authors supposed that enzymhistochemical differences might also exist. This hypothesis could be confirmed by the results obtained in the Macula densa- and the Goormaghtigh-cells (Tab. 1 and 2). Indeed, in both places the Isocitrate dehydrogenase- and the Malate dehydrogenase-activities are stronger in the guinea pig than in the rat. On the other hand, the Glucose-6-phosphate and the 6-Phosphogluconate dehydrogenases show clearly weaker activities in the guinea pig Macula-cells compared with those of the rat, where these two enzymes give by far the strongest reaction. Metabolic differences might be related to the described diversities of the enzyme equipment.
D000818:Animals; D003576:Electron Transport Complex IV / Q000378:metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006168:Guinea Pigs; D007606:Juxtaglomerular Apparatus / Q000201:enzymology; D007668:Kidney / Q000201:enzymology*; D008297:Male; D009246:NADH Tetrazolium Reductase / Q000378:metabolism; D010088:Oxidoreductases / Q000378:metabolism; D051381:Rats; D013385:Succinate Dehydrogenase / Q000378:metabolism
D010088:Oxidoreductases; D005954:Glucosephosphate Dehydrogenase; D013385:Succinate Dehydrogenase; D009246:NADH Tetrazolium Reductase; D003576:Electron Transport Complex IV
Enzymhistochemische Untersuchungen an den Macula- und Goormaghtigh-Zellen der Meerschweinchen-Niere