Fibroxanthosarcoma of bone.
A tumour arising from the body of the eighth thoracic vertebra is believed to be the first recordedexample of a primary fibroxanthosarcoma of bone. Apart from the absence of a demonstrable storiform pattern, the histology conformed to that of fibroxanthosarcoma of the soft tissues. Ultrastructural studies showed that asteroid-like bodies seen in the cytoplasm of some tumour cells consisted of aggregated centrioles surrounded by cytoplasmic vacuoles. The finding of Langerhans cell granules in some tumour cells supported their identification as histiocytes. These granules have not previously been recorded in the fibrous histiocytoma group of tumours.
D000368:Aged; D005354:Fibrosarcoma / Q000473:pathology*; D006644:Histiocytes / Q000648:ultrastructure; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D008297:Male; D008938:Mitosis; D009940:Organoids / Q000648:ultrastructure; D013125:Spinal Neoplasms / Q000473:pathology*; D013904:Thoracic Vertebrae / Q000473:pathology* / Q000648:ultrastructure