NMR in cancer. VII. Sodium-23 magnetic resonance of normal and cancerous tissues.
Sodium-23 magnetic resonance was performed on four types of cancers and six types of normal tissues of rats and mice. The spin-lattice relaxation time of the tumors was generally longer than that of the normal tissues, with the most marked difference occurring between rat liver (T1 = 6.5 msec) and Novikoff hepatoma (T1 =23.7 msec). Estimation of tissue sodium from the signal intensity of the resonance indicated that all four types of tumors contained more sodium than any of the normal tissues.
D000818:Animals; D002279:Carcinoma 256, Walker / Q000032:analysis; D002286:Carcinoma, Ehrlich Tumor / Q000032:analysis; D006528:Carcinoma, Hepatocellular / Q000032:analysis; D007422:Intestines / Q000032:analysis; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D008113:Liver Neoplasms; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051379:Mice; D009132:Muscles / Q000032:analysis; D009374:Neoplasms, Experimental / Q000032:analysis*; D009928:Organ Specificity; D051381:Rats; D012510:Sarcoma 180 / Q000032:analysis; D012964:Sodium / Q000032:analysis*; D013737:Testis / Q000032:analysis
D012964:Sodium