Bronchiolitis and asthma: possible common pathogenetic pathways.
A discussion of possible mechanism for virus-induced wheezing in normal and asthmatic children is presented. Presently attractive theories for immune injury in viral bronchiolitis include those which depend on pathology induced by types 1, 3, and 4 of Gell and Coombs. The continuum of viral bronchiolitis with virus-induced wheezing in young children who are labeled "asthmatic" argues for some common mechanism of bronchiolar obstruction.
D001249:Asthma / Q000209:etiology*; D001990:Bronchiolitis, Viral / Q000209:etiology* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007223:Infant; D012136:Respiratory Syncytial Viruses / Q000472:pathogenicity; D012229:Rhinovirus / Q000472:pathogenicity
D007073:Immunoglobulin E