title: Herpesvirus type 2: isolation from seminal vesicle and testes.
abstract: Reproductive tissues from 10 recent male cadavers were examined. Herpesvirus type 2 was isolated from testes, seminal vesicle, or both in 4 cases. This is the first report of the isolation of herpesvirus type 2 from human seminal vesicular tissue. The data support previous evidence that herpesvirus type 2 can be isolated from the reproductive tissues of males without active or prior infection and suggest that these tissues may serve as a reservoir for transmission of this virus. The study also documents, for the first time, the ability to culture herpesvirus type 2 in organ explants from cadaveric reproductive tissues with the subsequent release of infectious virus.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003470:Culture Media; D004197:Disease Reservoirs; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000382:microbiology; D012669:Seminal Vesicles / Q000382:microbiology*; D018139:Simplexvirus / Q000302:isolation & purification*; D013737:Testis / Q000382:microbiology*
chemical_list: D003470:Culture Media