title: Multiple regulatory events in the development of competence for genetic transformation in Haemophilus influenzae.
abstract: Cyclic adenosine 3',5'-monophosphate derepresses enzyme synthesis but does not yield high levels of transformability or detectable levels of competence-related envelope polypeptides. Additional regulatory events must trigger complete expression of competence.
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis; D002462:Cell Membrane / Q000201:enzymology; D002473:Cell Wall / Q000378:metabolism; D000242:Cyclic AMP / Q000494:pharmacology; D004269:DNA, Bacterial / Q000378:metabolism; D004794:Enzyme Repression / Q000187:drug effects; D006193:Haemophilus influenzae / Q000201:enzymology / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008070:Lipopolysaccharides / Q000096:biosynthesis; D008970:Molecular Weight; D010452:Peptide Biosynthesis; D011135:Polysaccharides, Bacterial / Q000096:biosynthesis; D014170:Transformation, Genetic
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial; D000242:Cyclic AMP; D007770:L-Lactate Dehydrogenase