[Histochemical study of the enzymes of glycogen metabolism in the human endometrium during the normal menstrual cycle].
The content of glycogen in the human endometrium is dependet on the activity of enzymes involved in processes of synthesis and dissociation of glicogen: glycogen-synthetase, phosphorilase and glycogen-6-phosphatase. The activation of "D" form of glycogensynthetase dependent on glucose-6-phosphate and the increase of the glycoogen quantity in the endometrium glands epithelium is observed in the period of growing gestagenic function of the ovaries. At the end of the secretory phase there occurs activation of the glycogen dissociation enzme-phosphorilase which goes in parallel with abrupt inhibition of the glycogensynthetase activity and disappearance or glycogen from the gland epithelium. The inhibition of glycogen synthetase is conditioned by a decreased level of intracellular glucose-6-phosphate which appears due to activation of glucose-6-phosphate in this period.
D004717:Endometrium / Q000201:enzymology*; D004847:Epithelial Cells; D004848:Epithelium / Q000378:metabolism; D005260:Female; D005952:Glucose-6-Phosphatase / Q000378:metabolism*; D006003:Glycogen / Q000378:metabolism; D006006:Glycogen Synthase / Q000378:metabolism*; D006801:Humans; D008598:Menstruation; D010053:Ovary / Q000502:physiology; D006005:Phosphorylases / Q000378:metabolism*
D006003:Glycogen; D006005:Phosphorylases; D006006:Glycogen Synthase; D005952:Glucose-6-Phosphatase
Gistokhimicheskoe issledovanie fermentov metabolizma glikogena v éndometrii cheloveka pri normal'nom menstrual'nom tsikle