False positive 51Cr release tests during post-transplant immunological monitoring due to recipient serum radioactive contamination.
The occurrence of false positive 51Cr release test results in post-transplant immunological monitoring of human kidney graft recipients due to 131I carryover from renograms is described. False positivity was detected in 7 instances in 4 recipients, and suspected in 12 instances in 7 recipients, in a series of 46 consecutive transplant recipients. Technical methods and controls to detect and prevent such false positivity are described.
D000920:Antibody-Dependent Cell Cytotoxicity; D002860:Chromium Radioisotopes / Q000627:therapeutic use*; D003165:Complement System Proteins; D005189:False Positive Reactions; D006801:Humans; D007553:Isotope Labeling; D016030:Kidney Transplantation; D007959:Lymphocyte Culture Test, Mixed
D002860:Chromium Radioisotopes; D003165:Complement System Proteins