Complete Klüver-Bucy syndrome in man.
A 22 year old right-handed man suffered a viral meningoencephalitis, possibly herpetic, resulting in bilateral damage to the temporal lobes as confirmed by appropriate clinical, electrophysiological and neuroradiological studies. Extended clinical neuropsychological evaluation documented all the characteristic features of the syndrome described by Klüver and Bucy following bilateral ablation of the temporal lobes in adult Rhesus monkeys, including "psychic blindness," oral exploration, hypermetamorphic impulse to action," lack of emotional responsiveness, aberrant sexual behavior, and an insatiable appetite. Additionally, a  severe Wernicke's aphasia and a profound memory disorder were evident. The significance of these features as regards limbic function in the human is discussed.
D000328:Adult; D001037:Aphasia / Q000150:complications / Q000209:etiology; D001519:Behavior; D001068:Feeding and Eating Disorders / Q000150:complications / Q000209:etiology; D006566:Herpesviridae Infections / Q000150:complications; D006716:Homosexuality / Q000150:complications / Q000209:etiology; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000150:complications / Q000209:etiology; D008590:Meningoencephalitis / Q000150:complications*; D011612:Psychosurgery / Q000009:adverse effects*; D012725:Sexual Behavior; D013577:Syndrome; D013702:Temporal Lobe / Q000502:physiology*