The retina in type 5 hyperlipoproteinemia.
Of two patients with type 5 hyperlipoproteinemia, one exhibited lipemia retinalis with multiple retinal hemorrhages and intraretinal lipid extravasations. Postmortem examination showed hemorrhages in the inner retinal layers and lipid deposits largely in the outer plexiform layer. Lipid within the walls of the retinal vessels was demonstrated by light and electron microscopy. The second patient exhibited visual loss due to progressive obstruction of retinal vessels with white material presumed to be lipid. Findings were confined to one eye.
D000328:Adult; D001344:Autopsy; D002914:Chylomicrons / Q000097:blood*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000473:pathology*; D008079:Lipoproteins, VLDL / Q000097:blood*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D012160:Retina / Q000473:pathology*; D012166:Retinal Hemorrhage / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology*; D014280:Triglycerides / Q000097:blood*
D002914:Chylomicrons; D008079:Lipoproteins, VLDL; D014280:Triglycerides