Absent pyruvate inhibition of pyruvate dehydrogenase kinase in lactating rat mammary gland following various treatments. Removal of circulating insulin and prolactin and exposure to protein synthesis inhibitors.
D000818:Animals; D001971:Bromocriptine / Q000494:pharmacology; D003513:Cycloheximide / Q000494:pharmacology; D005260:Female; D007328:Insulin / Q000097:blood*; D007774:Lactation; D008321:Mammary Glands, Animal / Q000187:drug effects / Q000201:enzymology*; D008928:Mitochondria / Q000201:enzymology; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*; D047428:Protein Kinase Inhibitors; D011494:Protein Kinases / Q000378:metabolism*; D011691:Puromycin / Q000494:pharmacology; D011768:Pyruvate Dehydrogenase Complex / Q000037:antagonists & inhibitors / Q000378:metabolism*; D011773:Pyruvates / Q000494:pharmacology; D051381:Rats; D013311:Streptozocin / Q000494:pharmacology
D007328:Insulin; D047428:Protein Kinase Inhibitors; D011768:Pyruvate Dehydrogenase Complex; D011773:Pyruvates; D001971:Bromocriptine; D011691:Puromycin; D013311:Streptozocin; D011388:Prolactin; D003513:Cycloheximide; D011494:Protein Kinases