Mutagenicity testing with Salmonella typhimurium strains. II. The effect of unusual phenotypes on the mutagenic response.
The enhanced sensitivity of some Salmonella typhimurium strains to the mutagenic action of a number of chemicals appears to be due to the defect in the uvrB gene product and not to an inability to produce H-2-S or to the absence of formic acid hydrogenlyase which also characterizes these strains.
D000445:Aldehyde Oxidoreductases / Q000378:metabolism; D001386:Azides / Q000494:pharmacology; D004852:Epoxy Compounds / Q000494:pharmacology; D005561:Formates; D005796:Genes; D008698:Mesylates / Q000494:pharmacology; D009153:Mutagens / Q000494:pharmacology*; D009154:Mutation; D009573:Nitrites / Q000494:pharmacology; D010641:Phenotype; D011420:Propiolactone / Q000494:pharmacology; D014176:Protein Biosynthesis; D012486:Salmonella typhimurium / Q000145:classification / Q000187:drug effects* / Q000378:metabolism
D001386:Azides; D004852:Epoxy Compounds; D005561:Formates; D008698:Mesylates; D009153:Mutagens; D009573:Nitrites; D011420:Propiolactone; D000445:Aldehyde Oxidoreductases