title: Properties of cells transformed by DNA tumor viruses.
abstract: Transformation by the papovaviruses, SV40 and polyoma, is reviewed briefly, including factors that affect the frequency of transformation. Virus markers useful in the determination of the etiology of virus-free tumors are described, including viral DNA, viral mRNA, virus-induced antigens, and the rescue of infectious virus. Finally, the evidence that viral genes are involved in the maintenance of transformation is presented.
mesh_terms: D002471:Cell Transformation, Neoplastic; D004261:DNA Replication; D009154:Mutation; D010641:Phenotype; D011120:Polyomavirus; D013539:Simian virus 40; D014779:Virus Replication