Granular cell tumors of the central nervous system of rats.
On the basis of our study of 12 cases of granular cell tumors in the brains of rats of different inbred strains, it seems that granular cell tumors are not rate in the central nervous system of untreated, aging BN/Bi rats. In none were metastases found. Awareness of the occurrence of these tumors in the central nervous system of these rats may stimulate further studies into the cellular origin of granular cell tumors that form in the central nervous system of the rat and might help to elucidate the origin of these tumors in general.
D000818:Animals; D001932:Brain Neoplasms / Q000453:epidemiology / Q000473:pathology*; D002528:Cerebellar Neoplasms; D005260:Female; D008297:Male; D009379:Neoplasms, Muscle Tissue / Q000453:epidemiology / Q000473:pathology*; D051381:Rats; D011914:Rats, Inbred BN