title: Changes in protein levels in perfusates of freely moving cats: relation to behavioral state.
abstract: Perfusates from the brains of freely moving cats, obtained by means of a push-pull cannula, contain high concentrations of proteins. The levels vary in a cyclic fashion and are higher during rapid eye movement sleep than during the waking state. The proteins represent a distinctive class of tissue protein and their changing levels appear to reflect an alteration in the protein content of the extracellular space of brain related to behavioral state.
mesh_terms: D000818:Animals; D001921:Brain / Q000166:cytology / Q000378:metabolism*; D002404:Catheterization; D002415:Cats; D002940:Circadian Rhythm; D005110:Extracellular Space / Q000378:metabolism; D006624:Hippocampus / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D010477:Perfusion; D012154:Reticular Formation / Q000378:metabolism; D012890:Sleep; D012895:Sleep, REM
chemical_list: D009419:Nerve Tissue Proteins