Influence of repair on the specificity of ultraviolet-induced reversion of an ochre alleles of the structural gene for iso-1-cytochrome c.
The specific action of UV on the reversion of the ochre allele cycl-9, in which 21 out of 23 revertants have been shown to arise from A-T-to-G.C transitions at position one in the UAA codon, was found to depend on the function of the RAD6 gene, since cycl-9 reversion occurred by a variety of single-base-pair substitutions in a strain carrying the rad6-1 allele.
D000483:Alleles; D003062:Codon; D003574:Cytochrome c Group / Q000031:analogs & derivatives*; D003575:Cytochromes c1 / Q000096:biosynthesis*; D004260:DNA Repair; D005796:Genes; D011831:Radiation Genetics; D014466:Ultraviolet Rays
D003062:Codon; D003574:Cytochrome c Group; D003575:Cytochromes c1