title: Sister chromatid exchange detection. The method and its usefulness in genetic counseling.
abstract: The sister chromatid exchange (SCE) detection was performed in the blood cultures from two human subjects, progenitors of some congenitally malformed children and from one patient with presumed symptoms of Bloom's syndrome. The usefulness of the SCE detection in genetic counseling and for the estimation of induced chromosomal lesions is discussed.
mesh_terms: D000328:Adult; D002478:Cells, Cultured; D002842:Chromatids / Q000648:ultrastructure*; D002869:Chromosome Aberrations; D000013:Congenital Abnormalities / Q000235:genetics; D005260:Female; D005817:Genetic Counseling; D005821:Genetic Techniques; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure*; D008297:Male