Pregnancy interrupting effects of some bacterial toxins.
Embryotoxic properties of Shigella dysenteriae and Clostridium perfringens toxins, of E. coli endotoxin, V. cholerase and E. coli enterotoxins were compared in mice. E. coli endotoxin has embryotoxic effects at all stages of pregnancy. E. coli enterotoxin V. cholerae enterotoxin and Shigella dysenteriae toxin are most effective mainly at earlier stages of pregnancy. Clostridium perfringens toxin has no embryotoxic effect.
D000020:Abortifacient Agents, Nonsteroidal; D000818:Animals; D003016:Clostridium perfringens; D004622:Embryo, Mammalian / Q000187:drug effects; D004731:Endotoxins / Q000494:pharmacology*; D004926:Escherichia coli; D005260:Female; D051379:Mice; D011247:Pregnancy / Q000187:drug effects*; D012762:Shigella dysenteriae
D000020:Abortifacient Agents, Nonsteroidal; D004731:Endotoxins