[Morphogenesis of eleastotic transformation of breast cancer stroma (author's transl)].
Within the tissue proteins in stroma of breast cancer occured multifocal elastotic transformations. The transformations concern collagen bundles that are devoided of mucopolysaccharide substance. The fields of degenerated connective tissue take on the capacities to dye like elastic fibres. The authors suggest that the increase of elastotic material in stroma of breast cancer is bound with the collagen degradation that is caused by metabolites of cancer tissue. The phenomenon occured in all age groups and is not closely bound with the grade of histological malignancy of cancer.
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology*; D002277:Carcinoma / Q000378:metabolism / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000378:metabolism / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D003094:Collagen / Q000378:metabolism; D004547:Elastic Tissue / Q000473:pathology*; D005260:Female; D005347:Fibroblasts / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism; D006801:Humans; D008875:Middle Aged
D006025:Glycosaminoglycans; D003094:Collagen
Die Morphogenese der clastotischen Veränderungen des Mammakarzinomstromas