title: Stimulation by organic solvents and detergents of conversion of L-sorbose to L-sorbosone by Gluconobacter melanogenus IFO 3293.
abstract: Treatment of Gluconobacter melanogenus IFO 3293 cells with benzene, carbon tetrachloride, cyclohexane, deoxycholate, toluene, or xylene stimulated their conversion of L-sorbose to L-sorbosone two- to threefold. The degree of stimulation depended upon the length of exposure time to the agent and the age of the G. melanogenus cells. A rapid decrease in viability of the cells and degradation of cell RNA was noted after treatment with the effective agents. The G. melanogenus cells were unable to absorb L-sorbose actively after toluene treatment.
mesh_terms: D000367:Age Factors; D003902:Detergents / Q000494:pharmacology*; D011113:Polymyxins / Q000494:pharmacology; D011548:Pseudomonadaceae / Q000187:drug effects / Q000378:metabolism*; D012997:Solvents / Q000494:pharmacology*; D013013:Sorbose / Q000031:analogs & derivatives / Q000378:metabolism*; D014050:Toluene / Q000494:pharmacology
chemical_list: D003902:Detergents; D011113:Polymyxins; D012997:Solvents; D014050:Toluene; D013013:Sorbose