Effects of intraventricular injections of N-6,O-2-Dibutyryl adenosine 3,5-monophosphate on the rat brain cholinergic system.
Intraventricular injections of dibutyryl cyclic AMP effected increases of acetylcholine in the cerebral cortex-striatal and subcortical regions. No increase in choline acetyltransferase activity was observed; however, there was a significant decrease in acetylcholinesterase activity in the subcortical region.
D000109:Acetylcholine / Q000378:metabolism*; D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D003994:Bucladesine / Q000494:pharmacology*; D002540:Cerebral Cortex / Q000378:metabolism; D002552:Cerebral Ventricles; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D007267:Injections; D007275:Injections, Intravenous; D010275:Parasympathetic Nervous System / Q000187:drug effects; D051381:Rats; D013997:Time Factors
D003994:Bucladesine; D002795:Choline O-Acetyltransferase; D000110:Acetylcholinesterase; D000109:Acetylcholine