Langerhans cells trap tick salivary gland antigens in tick-resistant guinea pigs.
In the infested skin of tick-resistant guinea pigs, indirect immunofluorescence techniques have revealed that antigens from the ticks' salivary glands are associated with discrete dendritic cells in the epidermis. Evidence is presented to support the suggestion that these antigen-retaining cells are Langerhans cells.
D000251:Adenosine Triphosphatases; D000818:Animals; D000941:Antigens / Q000276:immunology*; D003712:Dendrites / Q000201:enzymology / Q000276:immunology; D005455:Fluorescent Antibody Technique; D006168:Guinea Pigs; D007801:Langerhans Cells / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology; D012469:Salivary Glands / Q000276:immunology*; D013987:Ticks
D000941:Antigens; D000251:Adenosine Triphosphatases