[A new insulin radioimmunotest and its use in the determination of anti-insulin antibodies].
Acetylation of insulin with 3H-acetic anhydride resulted in the predominant 3H-labeling at the aminoterminal position of the B-chain (B1). The labeled insulin was unchanged in its immunologic reactivity as compared to native insulin. It was used in a second antibody radioimmunoassay for the detection of antiinsulin-antibodies in insulin-dependent patients with Diabetes mellitus.
D003920:Diabetes Mellitus / Q000276:immunology*; D006801:Humans; D007105:Immune Complex Diseases / Q000276:immunology; D007328:Insulin / Q000276:immunology*; D007330:Insulin Antibodies / Q000032:analysis*; D007333:Insulin Resistance; D011863:Radioimmunoassay
D007328:Insulin; D007330:Insulin Antibodies
Ein neuer Insulin-Radioimmuntest und seine Anwendung auf die Bestimmung von Antiinsulinantikörpern.