Biosynthesis of sphingomyelin in rat liver endoplasmic reticulum.
Rat liver microsomal sphingomyelin synthetase (CDPcholine: N-acylspingosine choline phosphotransferase (EC 2.7.8.3)) has been shown to be markedly stimulated by ATP and pantothenic acid derivatives such as CoA, pantethine, pantetheine and 4'-phosphopantetheine.
D000818:Animals; D003065:Coenzyme A / Q000494:pharmacology; D000242:Cyclic AMP / Q000494:pharmacology; D004721:Endoplasmic Reticulum / Q000201:enzymology*; D008862:Microsomes, Liver / Q000201:enzymology*; D010084:Oxidation-Reduction; D010205:Pantothenic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D010770:Phosphotransferases / Q000378:metabolism*; D051381:Rats; D012265:Ribonucleotides / Q000494:pharmacology; D013109:Sphingomyelins / Q000096:biosynthesis*; D013329:Structure-Activity Relationship
D012265:Ribonucleotides; D013109:Sphingomyelins; D010205:Pantothenic Acid; D000242:Cyclic AMP; D010770:Phosphotransferases; D003065:Coenzyme A