[Interrelationship of the mediator receptors in the terminals of the afferent nerves of the cornea of the eye].
In local application of substances with a mediator action (adrenaline, acetylcholine, histamine) and blockers of specific receptors (dihydroergotoxin, inderal, atropine and of subcutaneous dimedrol) together with dicaine it was possible to reveal a distinct presence in the cornea of the eye of the mediator receptors capable of influencing one another. Pharmacological analysis permitted a supposition to be made that there were two receptor systems in the sensory nerve endings of the cornea; these systems were in reciprocal inhibitory relations; due to this their regular influence on the processes of excitation and inhibition is effected in the sensory nerve ending.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D003315:Cornea / Q000294:innervation*; D004088:Dihydroergotoxine / Q000494:pharmacology; D004155:Diphenhydramine / Q000494:pharmacology; D004837:Epinephrine / Q000494:pharmacology; D006632:Histamine / Q000494:pharmacology; D009433:Neural Inhibition; D009474:Neurons / Q000502:physiology*; D009475:Neurons, Afferent / Q000187:drug effects / Q000502:physiology*; D011433:Propranolol / Q000494:pharmacology; D011817:Rabbits; D011984:Sensory Receptor Cells / Q000187:drug effects / Q000502:physiology*; D009435:Synaptic Transmission; D013748:Tetracaine / Q000494:pharmacology
D013748:Tetracaine; D004088:Dihydroergotoxine; D001285:Atropine; D006632:Histamine; D004155:Diphenhydramine; D011433:Propranolol; D000109:Acetylcholine; D004837:Epinephrine
O vzaimootnosheniiakh mediatornykh retseptorov v okonchaniiakh afferentnykh nervov rogovitsy glaz