title: [Hyper- and hypo-reactivity in mice with regard to the induction of virus inhibitory factor or interferon].
abstract: 1. IF induction in mice with Newcastle disease virus produced hyperreactivity on subsequent induction with certain doses of poly I:C. 2. Laparotomy or intraperitoneal injection with air caused temporary hyporeactivity of spleen and lungs on IF induction with endotoxin. Laparotomy in splenectomised mice did not affect IF formation in lungs.
mesh_terms: D000388:Air; D000818:Animals; D007372:Interferons / Q000096:biosynthesis*; D007700:Kinetics; D007813:Laparotomy; D008168:Lung / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D009522:Newcastle disease virus; D011070:Poly I-C / Q000494:pharmacology*; D013154:Spleen / Q000187:drug effects / Q000378:metabolism; D013156:Splenectomy
chemical_list: D007372:Interferons; D011070:Poly I-C
vernacular_title: Hyper- et hypo-réactivité de la souris vis-à-vis de l'induction du facteur inhibiteur des virus ou interféron.