Acrylamide encephaloneuropathy due to well water pollution.
All five members of a family developed subacutely mental confusion and/or truncal ataxia. Symptoms and signs of polyneuropathy were seen later. The well water in the patients' home contained 400 ppm acrylamide. The present cases are unique in that they are cases of acrylamide poisoning induced by oral intake and percutaneous penetration, and that central nervous system symptoms were prominent.
D000178:Acrylamides / Q000506:poisoning*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001259:Ataxia / Q000139:chemically induced; D001927:Brain Diseases / Q000139:chemically induced; D002648:Child; D003221:Confusion / Q000139:chemically induced; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008569:Memory Disorders / Q000139:chemically induced; D051379:Mice; D009422:Nervous System Diseases / Q000139:chemically induced* / Q000453:epidemiology; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced; D013064:Speech Disorders / Q000139:chemically induced; D014873:Water Pollutants / Q000506:poisoning*; D014874:Water Pollutants, Chemical / Q000506:poisoning*
D000178:Acrylamides; D014873:Water Pollutants; D014874:Water Pollutants, Chemical