title: [Advances in topical therapy of skin diseases (author's transl)].
abstract: The anti-inflammatory effect of the new topical corticosteroid fluocortin butyl ester is approximately equal to that of hydrocortisone acetate but it has the advantage that systemic side-effects are lacking. Vitamin A acid and benzoyl peroxide have brought significant advances in the topical treatment of acne. For the treatment of chloasma and other hyperpigmentations the combination of vitamin A acid and hydroquinone with a corticoid is considerably more effective than any of the single components alone. Povidone-iodine with its extraordinarily low sensitization rate has proved useful for external antimicrobial treatment. Extensive or multiple precancerous lesions are effectively treated with 5-fluorouracil. New hair growth can be induced in alopecia areata by the local application of DNCB.
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy; D000287:Administration, Topical; D000505:Alopecia / Q000188:drug therapy; D001585:Benzoyl Peroxide / Q000627:therapeutic use; D004137:Dinitrochlorobenzene / Q000627:therapeutic use; D005448:Fluocortolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D006873:Hydroquinones / Q000627:therapeutic use; D010859:Pigmentation Disorders / Q000188:drug therapy; D011230:Precancerous Conditions / Q000188:drug therapy; D012871:Skin Diseases / Q000188:drug therapy*; D014212:Tretinoin / Q000627:therapeutic use
chemical_list: D004137:Dinitrochlorobenzene; D006873:Hydroquinones; D014212:Tretinoin; D005448:Fluocortolone; D005472:Fluorouracil; D001585:Benzoyl Peroxide
vernacular_title: Fortschritte in der dermatologischen Lokaltherapie.