title: [Ocular signs in cases of down's syndrome (author's transl)].
abstract: 420 mongoloid children aged between one month and 14 years were examined in a special ophthalmology department for disabled children employing biomicroscopy, retinoscopy under atropine and, if possible, visual acuity testing. Epicanthal folds were present in 46%, mongoloid slanting of the lids in 72% of cases. A decrease in binocular vision was present in 40% of the children. Brushfield's spots were encountered in 86% of the patients in a circular arrangement, whilst in 7% only the temporal half of the iris was involved. Lens changes of a variable degree were present in altogether 55% of cases and an increase in the number of retinal vessels, as well as their radial arrangement, as described by Williams, were documented in 46% of the cases. A comparison of the incidence and degree of refractive anomalies in mongoloid and normal children was undertaken. The present findings are discussed and compared with the results of other investigators.
mesh_terms: D000293:Adolescent; D002386:Cataract / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications*; D005132:Eye Manifestations; D005143:Eyelids / Q000002:abnormalities; D006801:Humans; D007223:Infant; D012029:Refraction, Ocular; D012171:Retinal Vessels / Q000473:pathology; D013285:Strabismus / Q000209:etiology; D014786:Vision Disorders / Q000209:etiology
vernacular_title: Ophthalmologische Symptome beim Down-Syndrom.