Basal cell carcinomas and basal cell carcinoma-like changes overlying dermatofibromas.
Three patients had pigmented nodular basal cell carcinomas overlying dermatofibromas and 19 patients had basal cell carcinoma-like changes. We agree with the view generally held that acanthosis, pseudoepitheliomatous hyperplasia, basal cell buddings, and hair follicle-like proliferations of basal cells represent reactive changes of a spectrum of epidermal alterations overlying dermatofibromas. Contrary to the general opinion, however, we believe that basal cell carcinoma-like changes, superficial multicentric basal cell carcinomas, and nodular basal cell carcinomas represent neoplastic changes of such a spectrum.
D000328:Adult; D002280:Basal Cell Carcinoma / Q000150:complications / Q000473:pathology*; D005260:Female; D005350:Fibroma / Q000150:complications / Q000473:pathology*; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D008297:Male; D008545:Melanoma / Q000473:pathology; D008875:Middle Aged; D009506:Nevus / Q000473:pathology; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*