The effect of mycoplasmas on replication and plaquing ability of Herpes simplex virus.
M. arginini, an arginine utilizer, can decrease the yield of Herpes simplex virus, type 1 grown in Vero cells. M. arginini can also cause a reduction in number and size of plaques produced by HSV.  The reduction in titer and plaque size produced in M. arginini-infected cells can be reversed by supplementing medium with additional arginine. A. laidlawii, a nonarginine utilizing mycoplasma, had no effect on the growth of HSV.
D000818:Animals; D001120:Arginine / Q000494:pharmacology; D002417:Cattle; D002460:Cell Line; D002470:Cell Survival; D000882:Haplorhini; D006462:Hemolytic Plaque Technique; D007668:Kidney; D009175:Mycoplasma Infections / Q000150:complications* / Q000382:microbiology; D018139:Simplexvirus / Q000187:drug effects / Q000276:immunology; D014779:Virus Replication
D001120:Arginine