Comparisons of surface markers on Herpesvirus-associated lymphoid cells of nonhuman primates and established human lymphoid cell lines.
Herpesvirus saimiri (HVS)-owl monkey lymphoid cells were found to have high levels of surface receptor for sheep erythrocytes and erythrocytes of 3 other species. These HVS-lymphoid cells lacked a receptor for modified complement. Lymphoid cells of one HVS-owl monkey line showed evidence for the presence of surface immunofluorescent staining with anti-kappa chain serum. Cells of an established HVS-marmoset lymphoid line had similar surface markers. Of 4 established human lymphoid cell lines, all lacked a receptor for sheep erythrocytes, 3 showed evidence for the presence of receptor for modified complement, and 3 showed immunofluorescent evidence for the presence on the surface of both heavy and light chain immunoglobulin. Preliminary data on an established Epstein-Barr virus (EBV)-owl monkey lymphoid cell line indicated a lack of receptor for sheep erythrocytes, presence of receptor for modified complement, and surface immunofluorescent staining with both anti-heavy and anti-light chain sera.
D000818:Animals; D001666:Binding Sites, Antibody; D002460:Cell Line; D003165:Complement System Proteins; D004912:Erythrocytes / Q000276:immunology; D000882:Haplorhini; D006564:Herpesviridae; D006567:Herpesvirus 2, Saimiriine; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D007145:Immunoglobulin kappa-Chains; D008223:Lymphoma / Q000209:etiology / Q000276:immunology*; D009374:Neoplasms, Experimental / Q000276:immunology; D011947:Receptors, Antigen, B-Cell; D012756:Sheep / Q000276:immunology
D007145:Immunoglobulin kappa-Chains; D011947:Receptors, Antigen, B-Cell; D003165:Complement System Proteins