Daily variation in concentration of plasma corticosteroid in hypophysectomized rats.
A daily variation in the concentration of plasma corticosteroid hormone is present in hypophysectomized rats implanted with pellets of adrenocorticotropic hormone (ACTH) and thyroxine. Although ACTH is necessary to maintain a functional adrenal, and thyroxine is required to permit the expression of the plasma corticosteroid rhythm, a normal daily variation in plasma corticosteroid concentration does not appear to depend on the periodic release of pituitary hormones.
D000305:Adrenal Cortex Hormones / Q000097:blood*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000818:Animals; D002940:Circadian Rhythm; D007016:Hypophysectomy; D008297:Male; D051381:Rats; D013974:Thyroxine / Q000494:pharmacology
D000305:Adrenal Cortex Hormones; D000324:Adrenocorticotropic Hormone; D013974:Thyroxine