title: Production of human lens capsule illustrated by a case of chronic lenticular chalcosis.
abstract: The osmiophilic  capsular inclusion bodies in a case of  accidental lenticular chalcosis have been used as an in vivo indicator of capsular production. Copper stimulation and hence inclusion impregnation lasted 5 years and was stopped 2 years before removal of the lens by extraction of a foreign body. The amount of capsule produced in the two year period varied at different locations but it greatly exceeded the previously measured quantities. A capsular turnover is postulated with a capsular production by the epithelial cells and a surface resorption process. The production rate is considered to be relatively high in childhood and gradually subsides with increasing age.
mesh_terms: D000328:Adult; D003300:Copper / Q000378:metabolism; D005128:Eye Diseases / Q000209:etiology* / Q000378:metabolism; D005129:Eye Foreign Bodies / Q000150:complications*; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D007908:Lens, Crystalline / Q000378:metabolism / Q000648:ultrastructure*; D008297:Male
chemical_list: D003300:Copper