Cell-mediated immunity to antigens associated with endogenous murine C-type leukemia viruses.
Splenic lymphocytes from (BALB/c times A/J) F 1 mice are cytotoxic for BALB/c fibroblasts infected with an endogenous C-type leukemia virus, but are not cytotoxic for uninfected BALB/c fibroblasts. These results indicate that mice do not exhibit cell-mediated immune tolerance to antigens associated with endogenous C-type viruses.
D000818:Animals; D000956:Antigens, Viral; D002460:Cell Line; D003601:Cytotoxicity Tests, Immunologic; D005347:Fibroblasts; D005838:Genotype; D006648:Histocompatibility; D007111:Immunity, Cellular; D009052:Leukemia Virus, Murine / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D051379:Mice; D008805:Mice, Inbred A; D008807:Mice, Inbred BALB C; D012190:Retroviridae / Q000276:immunology*; D013045:Species Specificity; D013154:Spleen / Q000166:cytology / Q000276:immunology
D000956:Antigens, Viral