title: Neurological sequelae of malignant external otitis.
abstract: The neurological sequelae of malignant external otitis (MEO) form a characteristic syndrome. Following Pseudomonas external otitis, usually in an elderly, diabetic patient, either isolated facial nerve paralysis or multiple cranial nerve palsies develop. Once extensive neurological signs have developed, recovery rarely occurs. We saw a patient with MEO and multiple cranial nerve palsies who recovered following an extended course of gentamicin sulfate and carbenicillin disodium therapy.
mesh_terms: D000010:Abducens Nerve; D002228:Carbenicillin / Q000627:therapeutic use; D005158:Facial Paralysis / Q000188:drug therapy / Q000209:etiology*; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010032:Otitis Externa / Q000150:complications* / Q000209:etiology / Q000382:microbiology; D010243:Paralysis / Q000188:drug therapy / Q000209:etiology*; D010523:Peripheral Nervous System Diseases / Q000188:drug therapy / Q000209:etiology*; D011552:Pseudomonas Infections / Q000150:complications; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification
chemical_list: D005839:Gentamicins; D002228:Carbenicillin