[Action of an ATP analog, adenosine 5'-hyophosphophosphate in the reactions catalysed by hexokinase and fructose-6-phosphate kinase].
Adenosine 5'-hypoposphate phosphorylates glucose and fructose 6-phosphate in the presence of hexokinase and fructose 6-phosphate kinase respectively. It behaves as a competitive inhibitor versus ATP in the hexokinase reaction. Its affinity for the two enzymes is similar to that of ATP, the maximal velocities being however much lower.
D000255:Adenosine Triphosphate / Q000031:analogs & derivatives*; D001667:Binding, Competitive; D006593:Hexokinase / Q000037:antagonists & inhibitors*; D007700:Kinetics; D010770:Phosphotransferases / Q000037:antagonists & inhibitors*
D000255:Adenosine Triphosphate; D010770:Phosphotransferases; D006593:Hexokinase
Action d'un analogue de l'ATP l'adenosine 5'-hypophosphosphosphate dans les réactions catalysées par l'héxokinase et la fructose 6-phosphate kinase