Evidence for recombination between two different immunological types of foot-and-mouth disease virus.
Recombination was observed between temperature-sensitive (ts) mutants of two immunological types of foot-and-mouth disease virus which were distinguishable by two marker characteristics in addition to their antigenic type. Putative ts+ recombinants were isolated and the segregation patterns of their marker characteristics examined. The results are discussed in terms of the origin of new sub-type strains.
D000956:Antigens, Viral; D005537:Aphthovirus / Q000187:drug effects / Q000276:immunology; D006146:Guanidines / Q000494:pharmacology; D006358:Hot Temperature; D011995:Recombination, Genetic
D000956:Antigens, Viral; D006146:Guanidines