title: [Immune response dynamics during malignant tumor development].
abstract: Several mathematical models for the development of immune reaction during cancer diseases were plotted. The models describe both stimulation of the immune system by the tumor and its suppression. Non-specific inhibition was considered which resulted from glucose deficiency accompanying the development of a malignant tumor. The inhibiting effect of antitumour antibodies on toxic influence of limphocytes-killers was taken into account. The qualitative and quantitative study of the models showed the limits for the description of real interactions between tumour and organism by the mechanisms stated.
mesh_terms: D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000276:immunology / Q000378:metabolism; D005943:Gluconeogenesis; D005947:Glucose / Q000172:deficiency; D006003:Glycogen / Q000378:metabolism; D007694:Killer Cells, Natural / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D008433:Mathematics; D051379:Mice; D008954:Models, Biological; D009369:Neoplasms / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
chemical_list: D006003:Glycogen; D005947:Glucose
vernacular_title: Dinamika immunoĭ reaktsii pri razvitii zlokachestvennoĭ opukholi.