title: UV-induced reversion of a temperature-sensitive late mutant of simian virus 40 to a wild-type phenotype.
abstract: Irradiation of a simian virus 40 temperature-sensitive late mutant before infection of CV1 cells produces viruses that are phenotypically wild-type revertants. This probably occurs through suppression rather than true reversion because the revertants are produced at relatively high frequency and still have some properties of the original temperature-sensitive virus.
mesh_terms: D000818:Animals; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D000882:Haplorhini; D007668:Kidney; D009153:Mutagens; D009154:Mutation / Q000528:radiation effects*; D009604:Nitrosoguanidines; D010641:Phenotype; D011831:Radiation Genetics; D013539:Simian virus 40 / Q000254:growth & development / Q000528:radiation effects*; D013489:Suppression, Genetic; D013696:Temperature; D014466:Ultraviolet Rays; D014779:Virus Replication
chemical_list: D009153:Mutagens; D009604:Nitrosoguanidines