Effect of cyclic AMP and theophylline on phagocytotic activity of Tetrahymena pyriformis.
Dibutyril cAMP and the cPDE-inhibitor theophylline both enhance the phagocytotic activity of Tetrahymena. Theophylline and cAMP-activating histamine are synergistic. It follows that the cAMP-adenylcyclase system functions in the unicellular animal Tetrahymena.
D000818:Animals; D003994:Bucladesine / Q000494:pharmacology*; D006632:Histamine / Q000494:pharmacology; D010587:Phagocytosis / Q000187:drug effects; D013806:Theophylline / Q000494:pharmacology*
D003994:Bucladesine; D006632:Histamine; D013806:Theophylline