title: Investigations on the level of circulating eosinophils throughout a 24 hour period in parasitic disease.
abstract: Circulating absolute eosinophil levels were studied over a 24 hour period in a series of 10 patients with presumed parasitological disease. Seven of these ten had the distinct nocturnal increase and a percentage swing paralleling that found in normal subjects. Three patients had a reversed pattern. The latter were thought to have one or other form of filariasis. Two patients with loasis and a "physiological response" had suppression as anticipated to exogenous steroid. It is concluded that steroid administration will not separate parasitic from other causes of eosinophilia.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D002940:Circadian Rhythm / Q000187:drug effects*; D003937:Diagnosis, Differential; D004804:Eosinophils / Q000187:drug effects*; D006373:Helminthiasis / Q000175:diagnosis* / Q000469:parasitology; D006376:Helminths / Q000302:isolation & purification; D006801:Humans; D007958:Leukocyte Count; D008118:Loiasis / Q000175:diagnosis; D011239:Prednisolone / Q000494:pharmacology
chemical_list: D000324:Adrenocorticotropic Hormone; D011239:Prednisolone