title: Optic nerve manifestations of human congenital cytomegalovirus infection.
abstract: A Latin American male and a white female infant who had a cytomegalovirus infection on the first day of life had unilateral optic nerve hypoplasia. A white male infant who had cytomegalovirus isolated at 5 weeks of age had a unilateral partial coloboma of the optic nerve. A 4-month-old black infant with cytomegalovirus infection diagnosed at 2 days of age had a unilateral complete coloboma of the optic nerve associated with microphthalmia. Optic nerve involvement was an important manifestation of this disease.
mesh_terms: D002675:Child, Preschool; D002825:Chorioretinitis / Q000000981:diagnostic imaging; D003103:Coloboma / Q000000981:diagnostic imaging; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000151:congenital; D005132:Eye Manifestations; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009887:Ophthalmoscopy; D009902:Optic Neuritis / Q000000981:diagnostic imaging*; D011859:Radiography; D014786:Vision Disorders / Q000000981:diagnostic imaging