[Combination of chemotherapy and radiotherapy. I. Differential effect on the intestinal syndrome of irradiation combined with the drug administered in fractional doses and at various times].
We have studied the different effects on the intestinal syndrome between the administration of fractional doses of 5-Fu before and after irradiation. There is no difference between the diverse modalities and we obtain the same result when the 5-Fu is administered, fractionated or not, before or after the irradiation.
D000818:Animals; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage* / Q000627:therapeutic use; D007414:Intestinal Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D007928:Lethal Dose 50; D051379:Mice; D008807:Mice, Inbred BALB C; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000532:radiotherapy; D013997:Time Factors
D005472:Fluorouracil
Association de chimiothérapie et de radiothérapie. I. Effet différentiel sur le syndrome intestinal de l'association de l'irradiation et du fractionnement dans le temps de la drogue.