title: [The morphology of lung cancer and background changes according to bronchoscopic biopsy findings].
abstract: Results of a pathohistological investigation of bronchoscopy bioptic specimens in 523 patients, including 422 patients with cancer of the lungs, 7--with benign tumours of the lungs, 83,--with chronic nonspecific afflictions, and 11--with pulmonary tuberculosis, are discussed. A histological diagnosis of bronchogenic cancer was established in 210 out of 422 observations. In central cancer positive results of bronchobiopsy (i. i. revealing of tumour) were obtained in 198 (52.1%) out of 380 cases, in peripheral cancer - in 12 (28.5%) out of 42 cases. Investigations of bronchobiopsy specimens made it possible to establish: epidermoid cancer in 123 (58.6%) cases, microcellular anaplastic cancer in 58 (27.6%) of cases, adenocarcinoma in 15 (7.1%) of cases, macrocellular cancer in 1 (0.5%) case. In 13 observations (6.2%) the histological type of cancer was not identified. The specific gravity of epidermoid cancer was consistently greater than in investigations of operation and section material. Analysis of the background changes in bronchobiopsies in which no tumour tissue was observed showed a substantially lower incidence (P less than 0.01) of atypical metaplasia of the bronchial epithelium in chronic nonspecific diseases than in the bronchogenic cancer.
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D001706:Biopsy; D001999:Bronchoscopy; D018288:Carcinoma, Small Cell / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology*; D008297:Male
vernacular_title: Morfologiia raka legkogo i fonovykh izmeneniĭ po materialam bronkhoskopicheskikh biopsiĭ