Tumor incidence in Visna virus inoculated mice.
Mice (female Swiss albino) inoculated when newborn with Visna virus had tumors in 77% of cases when examined 8-12 months later. The tumors were mainly of the mammary carcinoma type. The tumor incidence in non-infected control animals was only 20%. In contrast, no increased incidence of tumors was observed among Visna virus-inoculated inbred mice (BALB/c, CBA and DBA) with low incidence of spontaneous mammary carcinoma.
D000818:Animals; D000831:Animals, Newborn; D001943:Breast Neoplasms / Q000209:etiology; D002471:Cell Transformation, Neoplastic; D005260:Female; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009369:Neoplasms / Q000209:etiology; D012328:RNA Viruses; D014790:Visna-maedi virus