Monolayer cultures of normal adult rat adrenocortical cells: steroidogenic responses to nucleotides, bacterial toxins and antimicrotubular agents.
Monolayer cultures of normal rat adrenocortical cells were treated with agents which stimulate steroidogenesis by Y-1 adrenal tumour cells. Choleragen was active, whereas cyclic nucleotides other than cyclic AMP, bacterial endotoxins and antimicrotubular agents were inactive.
D000302:Adrenal Cortex / Q000187:drug effects* / Q000378:metabolism; D000311:Adrenal Glands / Q000187:drug effects*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D003078:Colchicine / Q000494:pharmacology; D003345:Corticosterone / Q000378:metabolism*; D046508:Culture Techniques; D000242:Cyclic AMP / Q000494:pharmacology; D004768:Enterotoxins / Q000494:pharmacology*; D008297:Male; D009712:Nucleotides, Cyclic / Q000494:pharmacology*; D011034:Podophyllotoxin / Q000494:pharmacology; D011687:Purines / Q000494:pharmacology; D051381:Rats; D012263:Ribonucleosides / Q000494:pharmacology; D014734:Vibrio cholerae; D014747:Vinblastine / Q000494:pharmacology
D000972:Antineoplastic Agents, Phytogenic; D004768:Enterotoxins; D009712:Nucleotides, Cyclic; D011687:Purines; D012263:Ribonucleosides; D014747:Vinblastine; D000324:Adrenocorticotropic Hormone; D000242:Cyclic AMP; D011034:Podophyllotoxin; D003078:Colchicine; D003345:Corticosterone