Growth inhibition of sarcoma 180 induced by silica and talc.
In applying amorphous silica and talc in the site of solid Sarcoma 180 implants, the authors found a suppression and delay of tumor growth which was proveked by peritumoral foreign-body granulomas. Correlating these findings which those experiments which resulted in granulomas of hypersensitivity type, it may be suggested that any kind of peritumoral chronic inflammation enables an anti-tumor effect.
D000818:Animals; D002908:Chronic Disease; D005547:Foreign Bodies; D005549:Foreign-Body Reaction; D006099:Granuloma / Q000503:physiopathology; D007239:Infections; D008297:Male; D051379:Mice; D012510:Sarcoma 180 / Q000503:physiopathology*; D012822:Silicon Dioxide; D013627:Talc
D013627:Talc; D012822:Silicon Dioxide