Congenital granular-cell myoblastoma.
The clinical and pathologic features of congenital granular-cell myoblastoma in five infant girls are reported. One lesion, treated expectantly, progressively decreased in size and after 3 yr and 9 mo could not be detected, while two lesions which were imcompletely excised did not recur. It is suggested that congenital granular-cell myoblastoma is caused by an intrauterine stimulus, and that this stimulus may possible be production of estrogen by the fetus. Congential granular-cell myoblastoma should be treated expectantly or by limited excision, and has an excellent prognosis.
D002675:Child, Preschool; D004967:Estrogens / Q000096:biosynthesis; D005260:Female; D005333:Fetus / Q000378:metabolism; D006801:Humans; D007231:Infant, Newborn; D007573:Jaw Neoplasms / Q000151:congenital*; D008339:Mandibular Neoplasms / Q000151:congenital / Q000473:pathology / Q000601:surgery; D008441:Maxillary Neoplasms / Q000151:congenital / Q000473:pathology / Q000601:surgery; D009379:Neoplasms, Muscle Tissue / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D014062:Tongue Neoplasms / Q000151:congenital
D004967:Estrogens