Disseminated necrotizing myeloencephalitis: a herpes-associated neurological disease of horses.
Equine viral rhinopneumonitis type I virus was isolated from spinal cord and brain of a paraparetic horse with disseminated necrotizing myeloencephalitis. Necrotic arteriolitis,nonsuppurative necrotizing myeloencephalitis and Gasserian ganglioneuritis were present. On record were 12 more cases of horses with similar lesions. The horses had been ataxic or paretic for up to several weeks. A field survey indicated that 14 of 24 horses with acute myelitic signs developed them after recent exposure to respiratory disease.
D000818:Animals; D001921:Brain / Q000473:pathology; D004679:Encephalomyelitis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006564:Herpesviridae; D006566:Herpesviridae Infections / Q000382:microbiology / Q000473:pathology / Q000662:veterinary; D004861:Herpesvirus 1, Equid / Q000302:isolation & purification; D006734:Horse Diseases / Q000473:pathology; D006736:Horses; D009336:Necrosis; D013116:Spinal Cord / Q000382:microbiology / Q000473:pathology