title: [Elaboration of chloramphenicol acetyltransferase by cells of E. coli K-12 under conditions altering the intracellular concentration of cyclic adenosine-3',5'-monophosphate].
abstract: The influence of cAMP, ACTH and glucose on the stimulation of chloramphenicol acetyl transferase synthesis in the cells of E. coli CSH-2/R222 and E. coli WZ-78/R222. (cya855) was examined. Glucose proved to decrease the enzyme synthesis in E. coli CSH-2/R222, causing catabolite repression; 5 mM of cAMP and 1000 mug/ml ACTH overcame the latter. The enzyme synthesis in E. coli WZ-78/R222 was insensitive to the catabolite repression; as to ACTH - it failed to cause stimulation ofchloramphenicol acetyl transferase synthesis in E. coli WZ-78/R222.
mesh_terms: D000123:Acetyltransferases / Q000096:biosynthesis*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D002701:Chloramphenicol; D000242:Cyclic AMP / Q000378:metabolism* / Q000494:pharmacology; D004926:Escherichia coli / Q000201:enzymology* / Q000378:metabolism; D005947:Glucose / Q000494:pharmacology
chemical_list: D002701:Chloramphenicol; D000324:Adrenocorticotropic Hormone; D000242:Cyclic AMP; D000123:Acetyltransferases; D005947:Glucose
vernacular_title: Issledovanie vyrabotki khloramfenikolatsetiltransferazy kletkami E. coli K-12 v usloviiakh, izmeniaiushchikh vnutrikletochnuiu kontsentratsiiu tsiklicheskogo adenozin-3',5'-monofosfata