[Study of cortico-melanotropic activities in the anterior pituitary of an anencephalic and a normal newborn].
Immunofluorescence studies by-means of anti-beta (1-24) corticotropin, anti-alpha (17-39) ACTH; anti-beta-MSH were performed on the anterior pituitary of an at-term anencephalic newborn. They showed small and rare cortico-melanotropic cells, as compared to those seen in the anterior pituitary of newborns. The comparison of these data with experimental observations suggest a possible autonomy of corticotropin function, although under hypothalamus control.
D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000757:Anencephaly / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009074:Melanocyte-Stimulating Hormones / Q000378:metabolism*; D010902:Pituitary Gland / Q000503:physiopathology*; D010903:Pituitary Gland, Anterior / Q000473:pathology / Q000503:physiopathology*
D000324:Adrenocorticotropic Hormone; D009074:Melanocyte-Stimulating Hormones
Etude des activites cortico-melanotropes dans l'antehypophyse d'un anencephale et d'un nouveau-ne normal