A comparative study of iodine and potassium perchlorate metabolism in the laying hen.  1. incorporation of I-131 in chicken ova.
The uptake of 131-I in chicken ova was studied for 3 hours after a single intramuscular dose.  There was uptake as early as 10 minutes and it continued throughout the 3 hours in spite of a rapid decrease in blood activity.  The fast growing ova, weightin 0.5 to 2.0 grams, were the most efficient in the uptake of 131-I per unit weight.  Autoradiograms of the topographic distribution of 131-I showed a peripheral deposition.  When multiple doses were given, concentric rings in the growing ovocytes were seen.
D000818:Animals; D001345:Autoradiography; D002645:Chickens / Q000378:metabolism*; D005243:Feces / Q000032:analysis; D005260:Female; D007273:Injections, Intramuscular; D007455:Iodine / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D007457:Iodine Radioisotopes; D010058:Oviposition; D010063:Ovum / Q000378:metabolism*; D010472:Perchlorates / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism*; D013961:Thyroid Gland / Q000378:metabolism; D013974:Thyroxine / Q000378:metabolism; D013997:Time Factors
D007457:Iodine Radioisotopes; D010472:Perchlorates; D007455:Iodine; D013974:Thyroxine; D011188:Potassium