The effect of dianabol on the postirradiation disturbances of kininogenesis in rats.
The effect of Dianabol on the irradiation-induced disturbances in kininogenesis in rats was studied. It was found that Dianabol inhibits the postradiation increase of the kininforming activity in tissues of rats and decreases the level of kinins in irradiated animals. A probable role of these properties of Dianabol in its radioprotective activity is discussed.
D000818:Animals; D005767:Gastrointestinal Diseases / Q000209:etiology; D007704:Kininogens / Q000096:biosynthesis* / Q000097:blood; D007705:Kinins / Q000097:blood* / Q000502:physiology; D008099:Liver / Q000201:enzymology; D001121:Lysine Carboxypeptidase / Q000528:radiation effects; D008297:Male; D008696:Methandrostenolone / Q000494:pharmacology*; D007703:Peptidyl-Dipeptidase A / Q000528:radiation effects; D011832:Radiation Injuries / Q000209:etiology; D011833:Radiation Injuries, Experimental / Q000201:enzymology*; D051381:Rats; D013154:Spleen / Q000201:enzymology
D007704:Kininogens; D007705:Kinins; D008696:Methandrostenolone; D007703:Peptidyl-Dipeptidase A; D001121:Lysine Carboxypeptidase