Experimental models for DNA-RNA viral interactions: a brief review.
Evidences that demonstrate or imply the occurrence of DNA-RNA viral interactions in man and animals are reviewed. The concurrent presence of two dissimilar oncogenic viruses influenced responses both in vivo and in vitro. Cell-mediated immune responses to Marek's disease herpesvirus were altered in specific-pathogen-free chickens inoculated as embryos with an avian leukosis virus. The possible roles of immunological factors in the pathogenesis and control of tumor development associated with DNA-RNA viral interactions remain to be investigated.
D000818:Animals; D001354:Avian Leukosis Virus; D002645:Chickens; D046508:Culture Techniques; D006564:Herpesviridae; D008381:Herpesvirus 2, Gallid; D004854:Herpesvirus 4, Human; D007111:Immunity, Cellular; D008380:Marek Disease / Q000276:immunology; D008954:Models, Biological; D009374:Neoplasms, Experimental / Q000209:etiology* / Q000276:immunology; D012328:RNA Viruses; D010948:Viral Plaque Assay