Effect of vitamin A on tumor development in burned, unburned, and glucocorticoid-treated mice inoculated with an oncogenic virus.
High doses of vitamin A decreased the severity of tumor development in mice inoculated with a murine sarcoma virus; the same doses of vitamin A had no effect on the increased tumorigenesis seen in animals severely stressed with thermal injury or the increased tumorigenesis induced by exogenous glucocorticoid administration.
D000818:Animals; D000970:Antineoplastic Agents; D002056:Burns; D005938:Glucocorticoids; D008297:Male; D051379:Mice; D009053:Sarcoma Viruses, Murine; D012513:Sarcoma, Experimental / Q000188:drug therapy*; D014801:Vitamin A / Q000627:therapeutic use*
D000970:Antineoplastic Agents; D005938:Glucocorticoids; D014801:Vitamin A