title: The amino acid activation reaction catalyzed by methionyl-transfer rna synthetase: evidence for synergistic coupling between the sites for methionine adenosine and pyrophosphate.
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives / Q000378:metabolism; D000604:Amino Acyl-tRNA Synthetases / Q000378:metabolism*; D001665:Binding Sites; D001667:Binding, Competitive; D003956:Dialysis; D011756:Diphosphates / Q000378:metabolism; D004357:Drug Synergism; D004926:Escherichia coli; D007700:Kinetics; D008274:Magnesium / Q000378:metabolism; D008715:Methionine / Q000378:metabolism; D008718:Methionine-tRNA Ligase / Q000378:metabolism*; D008954:Models, Biological; D013050:Spectrometry, Fluorescence; D046249:Transfer RNA Aminoacylation; D014357:Trypsin
chemical_list: D011756:Diphosphates; D008715:Methionine; D014357:Trypsin; D000604:Amino Acyl-tRNA Synthetases; D008718:Methionine-tRNA Ligase; D008274:Magnesium; D000241:Adenosine