Ability of various factors to oppose the stimulatory effect of dibutyrylcyclic AMP on the release of melanocyte-stimulating hormone by the rat pituitary in vitro.
Various agents were tested for their ability to oppose the stimulatory effect of dibutyryl cyclic AMP on the release of the melanocyte-stimulating hormone from the rat neuro intermediate lobe in vitro. Only dopamine exhibited an inhibitory effect; serotonin, gamma-amino-butyric acid, tocinoic acid, tocinamide, the tripeptide Pro-Leu-Gly-NH2 and dibutyryl cyclic GMP were all ineffective.
D000818:Animals; D003994:Bucladesine / Q000037:antagonists & inhibitors*; D006152:Cyclic GMP / Q000031:analogs & derivatives / Q000494:pharmacology; D004298:Dopamine / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D009074:Melanocyte-Stimulating Hormones / Q000378:metabolism*; D010042:Ouabain / Q000494:pharmacology; D010121:Oxytocin / Q000031:analogs & derivatives / Q000494:pharmacology; D010455:Peptides / Q000494:pharmacology; D010902:Pituitary Gland / Q000187:drug effects / Q000378:metabolism*; D051381:Rats; D012701:Serotonin / Q000494:pharmacology; D013806:Theophylline / Q000494:pharmacology
D010455:Peptides; D012701:Serotonin; D010121:Oxytocin; D010042:Ouabain; D003994:Bucladesine; D009074:Melanocyte-Stimulating Hormones; D013806:Theophylline; D006152:Cyclic GMP; D004298:Dopamine