[Results of medical treatment of gastroduodenal ulcers with disordered gastric emptying].
The efficacy of medical treatment was studied in 53 patients with a peptic ulcer responsible for disturbed gastric emptying. An improvement in gastric emptying was noted in 38 cases and persistence of the disorder in 15 cases. These results were not related to the dose of anticholinergic drug, nor to the degree of disturbance in gastric emptying. Only one improvement was noted out of 7 cases of pyloric ulcer. A relapse of disturbed gastric emptying, occurred in 17 out of 38 patients who were initially improved. 25 patients out of 53 were finally operated on, 15 owing to persistence of the gastric emptying disturbance under treatment and 10 owing to a relapse. Out of 18 gastrectomy specimens, the ulcer was found to be healed in 7 cases. It seems that disturbed gastric emptying may be due to fixed deformities of the pylorus which are little changed by medical treatment, and minor disturbances of emptying regress well under treatment. Disturbed gastric emptying due tp pyloric ulcer is the most difficult to treat medically.
D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D005769:Gastrointestinal Motility; D006801:Humans; D008297:Male; D008875:Middle Aged; D010276:Parasympatholytics / Q000627:therapeutic use*; D010437:Peptic Ulcer / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery; D012008:Recurrence
D010276:Parasympatholytics
Résultats du traitement médical des ulcères gastro-duodénaux avec gêne à l'évacuation gastrique