[Myeloperoxidase synthesis in white mouse leukocytes].
H3-leucine incorporation in myeloperoxidase (MPO) and into total soluble protein (TSP) from leucocytes of peritoneal exudate of mice was determined by immunological procedure. Maximal H3-leucine incorporation was observed within 48 hours and 16 hours of exposition for MPO and TSP respectively. Half-life period of MPO was 2,6 days which is comparable with the duration of neutrophils maturation up to the stage of metamyelocyte. Apparently, no essential formation of MPO takes place at the level of band and segmented neutrophils.
D000818:Animals; D007930:Leucine / Q000378:metabolism; D007962:Leukocytes / Q000201:enzymology*; D008297:Male; D051379:Mice; D009195:Peroxidase / Q000096:biosynthesis*; D010544:Peroxidases / Q000096:biosynthesis*
D010544:Peroxidases; D009195:Peroxidase; D007930:Leucine
Izuchenie biosinteza mieloperoksidazy leĭkotsitov belykh mysheĭ