title: Cytochrome oxidase and ascorbic acid in the normal and regenerating tail of the scincid lizard, Mabuya carinata. A histophysiological study.
abstract: The concentration of ascorbic acid (AA) and the histochemical distribution of this vitamin together with cytochrome oxidase have been investigated in the normal and regenerating tail of the Scincid lizard, Mabuya carinata. An interesting aspect of this investigation is the observation of a total lack of cytochrome oxidase in both the normal and regenerating tail of the lizard, except for the differentiating phase. On the other hand, AA has been found to be present in the normal and regenerating tail with above normal levels during wound healing (twofold) and differentiation (fivefold). In the light of the poor cytochrome oxidase activity, the higher content of AA noted during regeneration has been construed to play a possible role in the respiratory mechanics of the regenerating lizard tail. Further, the importance of AA in cellular metabolism and the wound healing and differentiative processes have also been discussed.
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism*; D003576:Electron Transport Complex IV / Q000378:metabolism*; D008116:Lizards / Q000378:metabolism*; D012038:Regeneration; D013623:Tail / Q000502:physiology; D014945:Wound Healing
chemical_list: D003576:Electron Transport Complex IV; D001205:Ascorbic Acid