Effect of interferon on induction of S antigen by polyoma virus in BHK 21 cells.
A new surface antigen (S antigen) can be detected by immunofluorescence during the abortive transformation of hamster cells by polyoma virus. It was found that addition of interferon greatly reduces the percentage of cells positive for S antigen.
D000818:Animals; D000941:Antigens / Q000032:analysis*; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology*; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D006224:Cricetinae; D005455:Fluorescent Antibody Technique; D007372:Interferons / Q000494:pharmacology*; D007668:Kidney; D011120:Polyomavirus / Q000276:immunology*
D000941:Antigens; D007372:Interferons