Inhibtion of diplopterol synthesis in Tetrahymena pyriformis by a hypocholesteremic compound.
The hypocholesteremic compound, 3beta-(beta-dimethylaminoethoxy)-androst-5-en-17-one was earlier shown to inhibit the synthesis of tetrahymanol and two undentified lipids.  It now has been demonstrated that one of the unidentified compounds is diplopterol.
D015068:17-Ketosteroids / Q000494:pharmacology; D000736:Androstenes / Q000494:pharmacology*; D000818:Animals; D000924:Anticholesteremic Agents / Q000494:pharmacology*; D002845:Chromatography; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D005019:Ethyl Ethers / Q000494:pharmacology; D013058:Mass Spectrometry; D012822:Silicon Dioxide; D013261:Sterols / Q000096:biosynthesis*; D013769:Tetrahymena pyriformis / Q000187:drug effects / Q000378:metabolism*
D015068:17-Ketosteroids; D000736:Androstenes; D000924:Anticholesteremic Agents; D005019:Ethyl Ethers; D013261:Sterols; D012822:Silicon Dioxide