Recovery from encephalomyelitis caused by Herpesvirus simiae. Report of a case.
A 29-year-old monkey handler developed an acute encephalomyelitis with neuromuscular dysfunction that progressed to respiratory arrest on the 18th day of illness. Thereafter, with supportive care, the patient's condition improved steadily. The titer of neutralizing antibodies to H simiae rose from 1:4 (eighth day of illness) to 1:512 (47th day of illness). Apparently the fifth known survivor of H simiae (herpesvirus B) encephalomyelitis, this patient is also remarkable because of virtually complete recovery, apparently the second documented instance of a good outcome.
D000328:Adult; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D003168:Complement Fixation Tests; D004679:Encephalomyelitis / Q000209:etiology* / Q000276:immunology; D005455:Fluorescent Antibody Technique; D006564:Herpesviridae; D006566:Herpesviridae Infections / Q000209:etiology* / Q000276:immunology; D006568:Herpesvirus 1, Cercopithecine / Q000276:immunology; D006801:Humans; D008251:Macaca; D008297:Male; D009461:Neurologic Manifestations; D009784:Occupational Diseases / Q000209:etiology*; D012131:Respiratory Insufficiency / Q000209:etiology
D000914:Antibodies, Viral