[Determination of the variation in conduction speed of motor fibers and the effects of diphenylhydantoin (Phenytoin) and diazepam (Faustan)].
The variation in the speed of conduction of motor fibers of the ulnar nerve was determined by Hopf's double-stimulus method and compared with values obtained from the duration of muscular response potentials for differently spaced points of stimulation. However, the values obtained from the difference of the duration of response potentials are inadequate since the duration of potentials cannot always be determined accurately. After a ten-day administration of faustan (15 mg per day) or phenytoin (300 mg per day) there was observed a decrease especially in the minimum rate of conduction of motor fibers of the ulnar nerve.
D000293:Adolescent; D000328:Adult; D003975:Diazepam / Q000494:pharmacology*; D005071:Evoked Potentials; D006801:Humans; D008875:Middle Aged; D010672:Phenytoin / Q000494:pharmacology*; D009435:Synaptic Transmission / Q000187:drug effects*; D013997:Time Factors; D014459:Ulnar Nerve / Q000187:drug effects*
D010672:Phenytoin; D003975:Diazepam
Die Bestimmung der Streubreite der Leitgeschwindigkeit motorischer Fasern und ihre Beeinflussung durch Diphenylhydantoin (Phenytion) und Diazepam (Faustan)