[Comparison of the cytotoxicity of chloroform on mouse L cells by measurement of proteins and chromium 51 release].
The authors describe a new cytotoxicity test based on the classical measurement of the residual proteins after a contact time of 4 days between the produit tested and the mouse L cells. The results are expressed as a cytotoxic dose 50 with a confidence limit for the 95% threshold after a statistical treatment of the analytical data by a computerized method. For chloroform, this method is more sensitive that the classical cytotoxicity test involving the chrom 51 release.
D002725:Chloroform / Q000633:toxicity*; D002857:Chromium / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D007700:Kinetics; D007739:L Cells / Q000187:drug effects / Q000378:metabolism*; D008433:Mathematics; D011506:Proteins / Q000378:metabolism*
D011506:Proteins; D002857:Chromium; D002725:Chloroform
Etude comparative de la cytotoxicité du chloroforme sur les cellules L de souris par la mesure des protéines et du relargage du chrome 51.