Type III glycogenosis with multicore structures.
A case of an infantile type III glycogenosis (Forbes disease), confirmed by morphologic and biochemical studies, had light-microscopic, histochemical, and electron-microscopic evidence of multicore structures and type 1 fiber predominance with hypotrophy. This association is discussed with relation to the unusual clinical findings. The authors conclude that two distinct disease entities--Forbes disease and multicore myopathy--may coexist.
D000251:Adenosine Triphosphatases / Q000032:analysis; D002675:Child, Preschool; D005260:Female; D006003:Glycogen / Q000032:analysis; D006008:Glycogen Storage Disease / Q000473:pathology*; D006010:Glycogen Storage Disease Type III / Q000378:metabolism / Q000473:pathology*; D006651:Histocytochemistry; D006801:Humans; D008099:Liver / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009132:Muscles / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D009246:NADH Tetrazolium Reductase / Q000032:analysis; D013385:Succinate Dehydrogenase / Q000032:analysis
D006003:Glycogen; D013385:Succinate Dehydrogenase; D009246:NADH Tetrazolium Reductase; D000251:Adenosine Triphosphatases