The behaviour of some enzymes in the mouse liver due to chronic benzene intoxication.
1. Long trem benzene action brings about a permanent decrease in oxidoreductive enzymes and active transport as well as an inactivation of the lysosomal apparatus in liver-cells. 2. Particular liver lobule zones show different sensitivity to toxic action of benzene which might result from their different role in the processes of benzene biotransformation.
D000135:Acid Phosphatase / Q000378:metabolism*; D000818:Animals; D001554:Benzene / Q000506:poisoning*; D000252:Calcium-Transporting ATPases / Q000378:metabolism*; D002908:Chronic Disease; D008099:Liver / Q000201:enzymology* / Q000473:pathology; D008297:Male; D051379:Mice; D009246:NADH Tetrazolium Reductase / Q000378:metabolism*; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism*; D013385:Succinate Dehydrogenase / Q000378:metabolism*
D013385:Succinate Dehydrogenase; D009246:NADH Tetrazolium Reductase; D009247:NADH, NADPH Oxidoreductases; D000135:Acid Phosphatase; D000252:Calcium-Transporting ATPases; D001554:Benzene