[Hemodynamic, functional and biochemical effects of hypobaric hypoxia in rats treated with cytidine diphosphocholine].
Treatment with cytidine diphosphocholine (20 mg/kg i.p.) in rats induces, during acute hypoxia, a reduction of vegetative responses (no modification of cerebral blood flow), a protection of conditioned avoidance response and a stabilization of dopamine and noradrenaline cerebral levels.
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002794:Choline / Q000031:analogs & derivatives*; D003566:Cytidine Diphosphate Choline / Q000494:pharmacology*; D004298:Dopamine / Q000378:metabolism; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D000860:Hypoxia / Q000503:physiopathology*; D009638:Norepinephrine / Q000378:metabolism; D010100:Oxygen / Q000097:blood; D010992:Plethysmography, Impedance; D011312:Pressure; D051381:Rats
D003566:Cytidine Diphosphate Choline; D002794:Choline; D010100:Oxygen; D004298:Dopamine; D009638:Norepinephrine
Effets hémodynamiques, fonctionnels et biochimiques de l'hypoxie hypobare chez le rat traité par la cytidine diphosphocholine.