Formaldehyde-ozone-induced fluorescence and ACTH immunoreactivity in basophil tumours of the pituitary.
The ACTH cells of human foetal pituitary displayed intense formaldehyde-ozone-induced fluorescence characteristic of peptides or proteins with NH2-terminal tryptophan. Fourteen pituitary tumours were examined histochemically. Of these, two displayed formaldehyde-ozone-induced fluorescence. These two tumours were the only ones to exhibit ACTH immunoreactivity.
D000324:Adrenocorticotropic Hormone / Q000032:analysis*; D000368:Aged; D005260:Female; D005557:Formaldehyde; D006801:Humans; D008856:Microscopy, Fluorescence; D010126:Ozone; D010455:Peptides / Q000032:analysis*; D010903:Pituitary Gland, Anterior / Q000032:analysis; D010911:Pituitary Neoplasms / Q000032:analysis*; D014364:Tryptophan / Q000032:analysis*
D010455:Peptides; D005557:Formaldehyde; D010126:Ozone; D014364:Tryptophan; D000324:Adrenocorticotropic Hormone