[Influence of dibutyryl cyclic AMP and theophylline on the frequency of nuclear microtubules and microfilaments of sympathetic neurons].
In vivo dibutyryl cyclic AMP and theophylline, as does electrical stimulation, increase the frequency of nuclear microtubules and microfilaments in neurons of cat stellate ganglia. These and previous results lead us to conclude that cyclic AMP mediates the process of assembly of these two structural components from preformed protein subunits and thus triggers the formation of highly organized nuclear inclusions corresponding to the so-called intranuclear rodlets of light microscopy.
D000818:Animals; D003994:Bucladesine / Q000494:pharmacology*; D002415:Cats; D002467:Cell Nucleus; D000242:Cyclic AMP / Q000502:physiology; D008297:Male; D008870:Microtubules / Q000187:drug effects*; D009454:Neurofibrils / Q000187:drug effects; D009474:Neurons / Q000187:drug effects; D013233:Stellate Ganglion / Q000187:drug effects / Q000648:ultrastructure; D013564:Sympathetic Nervous System / Q000187:drug effects* / Q000502:physiology; D013806:Theophylline / Q000494:pharmacology*
D003994:Bucladesine; D013806:Theophylline; D000242:Cyclic AMP
Influence du dibutyryl AMP cyclique et de la théophylline sur la fréquence des microtubules et des microfilaments nucléaires des neurones sympathiques