[Activation of plasminogen in its immobilization].
Plasminogen is established to be able of transforming into the plasmin-like is compound when it is immobilized on aminoethyl cellulose by means of glutaric aldehyde. The plasminogen immobilized in such a way manifests a caseinolytic activity and is not activated additionally by streptokinase. The plasminogen immobilized on bromocyanogen-activated sepharose and cellulose, like soluble proenzyme, has no activity of plasmin and retains the ability of being activated with streptokinase in catalytic amounts.
D002364:Caseins; D002482:Cellulose; D004789:Enzyme Activation; D004800:Enzymes, Immobilized / Q000378:metabolism*; D005341:Fibrinolysin / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D010958:Plasminogen / Q000378:metabolism*; D012685:Sepharose; D013300:Streptokinase / Q000378:metabolism
D002364:Caseins; D004800:Enzymes, Immobilized; D010958:Plasminogen; D002482:Cellulose; D012685:Sepharose; D013300:Streptokinase; D005341:Fibrinolysin
Aktivatsiia plazminogena pri ego immobilizatsii.