Further immunization studies with mammary tumor virus.
A single i.m. dose of formalin-inactivated murine mammary tumor virus greatly reduces viral expression and mammary tumorigenesis in Af (tumor incidence, 39%) and RIIIf (tumor incidence, 11%) mice, which carry only  endogenous, gamete-transmitted virus. In C57BL mice, 1 mug of vaccine in Freund's complete adjuvant protects against later challenge with RIII virus.
D000818:Animals; D008325:Mammary Neoplasms, Experimental / Q000517:prevention & control*; D008324:Mammary Tumor Virus, Mouse / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL; D009500:Neutralization Tests; D014611:Vaccination; D014765:Viral Vaccines
D014765:Viral Vaccines