The effects of brain monoamine depletion on p-chlorophenyl-alanine-induced hypothermia.
I.p. administration of p-chlorophenylalanine produced a fall in rectal temperature in rats. The hypothermia was attenuated after pretreatment of the animals with 5,6-dihydroxytryptamine, but was unaffected after pretreatment of the animals with 6-hydroxydopamine.
D015115:5,6-Dihydroxytryptamine / Q000494:pharmacology; D000818:Animals; D001831:Body Temperature / Q000187:drug effects*; D001923:Brain Chemistry / Q000187:drug effects*; D010134:Fenclonine / Q000494:pharmacology*; D006892:Hydroxydopamines / Q000494:pharmacology; D008297:Male; D051381:Rats; D012701:Serotonin / Q000378:metabolism / Q000502:physiology*
D006892:Hydroxydopamines; D012701:Serotonin; D010134:Fenclonine; D015115:5,6-Dihydroxytryptamine