title: Structural comparison of hexosaminidases in primates.
abstract: 1. beta-Hexosaminidase (hex) structure was compared in various primates, using thin-layer isoelectric focusing on polyacrylamide gels and quantitative microcomplement fixation. 2. Isoelectric focusing revealed no intraspecies differences and similar interspecies patterns. 3. Hex A and B are evolving at a moderate, but equal, rate and in a manner consistent with accepted phylogenetic patterns. 4. Quantitative microcomplement fixation revealed a closer homology between human hex A and chimpanzee A or human hex B and chimpanzee hex B than between human hex A and human hex B.
mesh_terms: D000818:Animals; D054818:Hexosaminidase A; D054819:Hexosaminidase B; D006801:Humans; D007525:Isoelectric Focusing; D011323:Primates / Q000235:genetics*; D013045:Species Specificity; D001619:beta-N-Acetylhexosaminidases / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification
chemical_list: D054818:Hexosaminidase A; D054819:Hexosaminidase B; D001619:beta-N-Acetylhexosaminidases