Aldolase isoenzymes in liver cirrhosis and primary liver cell cancer.
The isoenzymatic pattern of aldolase was determined by immunoprecipitation with specific anti-aldolase A, B and C sera in 21 pathological liver tissues and in the sera of normals (n equals 20), liver cirrhotics (n equals 52) and hepatoma patients (n equals 22). The increase of aldolase A in primary liver cell carcinoma is not reflected in the sera of these patients, cannot be used for diagnostic purposes and is not hepatoma-specific.
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000201:enzymology*; D005634:Fructose-Bisphosphate Aldolase / Q000097:blood / Q000378:metabolism*; D006801:Humans; D007106:Immune Sera; D007527:Isoenzymes / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D008103:Liver Cirrhosis / Q000201:enzymology*; D008113:Liver Neoplasms / Q000201:enzymology*; D012756:Sheep / Q000276:immunology
D007106:Immune Sera; D007527:Isoenzymes; D005634:Fructose-Bisphosphate Aldolase