Serum beta-lipoprotein and other specific protein concentrations in patients with immunocytoma.
Serum beta-lipoprotein and other specific protein concentrations were measured in 56 patients suffering from multiple myelomatosis, "benign" paraproteinaemia or Waldenström's macroglobulinaemia and in 56 control subjects. The mean level of B-lipoprotein in untreated patients with multiple myelomatosis and macroglobulinaemia was significantly lower than that of the controls. Patients who responded to chemotherapy showed a rapid return to normal of the beta-lipoprotein concentration, while the level remained unchanged in most of those who did not.
D000368:Aged; D001797:Blood Protein Electrophoresis; D001798:Blood Proteins / Q000032:analysis; D002699:Chlorambucil / Q000627:therapeutic use; D002784:Cholesterol / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006452:Hemoglobinometry; D006801:Humans; D005779:Immunodiffusion; D008077:Lipoproteins, LDL / Q000097:blood*; D008297:Male; D008558:Melphalan / Q000627:therapeutic use; D008875:Middle Aged; D009101:Multiple Myeloma / Q000097:blood* / Q000188:drug therapy; D010265:Paraproteinemias / Q000097:blood*; D011239:Prednisolone / Q000627:therapeutic use; D014461:Ultracentrifugation; D008258:Waldenstrom Macroglobulinemia / Q000097:blood* / Q000188:drug therapy
D001798:Blood Proteins; D008077:Lipoproteins, LDL; D002699:Chlorambucil; D002784:Cholesterol; D011239:Prednisolone; D008558:Melphalan