Cytostatic treatment of polycythaemia rubra vera. Comparison of the effects of some cytostatics in 100 patients in a period of five years.
Experience with cytostatic treatment performed in patients with polycythaemia rubra vera is reviewed. The effectivity and side effects of the drugs applied are evaluated. Mannosulfan and mitobromitol were the drugs most sutiable for treatment. In certain special cases, 5-hydroxyurea was also satisfactory, while mitolactol was the least suitable.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D008297:Male; D008698:Mesylates / Q000627:therapeutic use; D008875:Middle Aged; D008927:Mitobronitol / Q000627:therapeutic use; D010761:Phosphorus Radioisotopes; D011087:Polycythemia Vera / Q000188:drug therapy*; D012075:Remission, Spontaneous
D000903:Antibiotics, Antineoplastic; D008698:Mesylates; D010761:Phosphorus Radioisotopes; D008927:Mitobronitol; D006918:Hydroxyurea