[Hypotensive action of arachidonic acid, slow acting analphylactic substance (SRS-A) and thromboxane A2 in rats].
In the rat, diethylcarbamazine, imidazole and L 8027 do not modify the hypotensive activity of PGE2 and arachidonic acid. The formation of SRS-A from arachidonic acid does not compete with the synthesis of PG in the cardiovascular system of the rat. The thromboxane A2 does not participate in the hypotensive activity of arachidonic acid in the rat.
D000818:Animals; D001095:Arachidonic Acids / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D006493:Heparin / Q000494:pharmacology; D007022:Hypotension / Q000139:chemically induced / Q000503:physiopathology*; D051381:Rats; D013189:SRS-A / Q000494:pharmacology*; D013928:Thromboxane A2 / Q000494:pharmacology*; D013931:Thromboxanes / Q000494:pharmacology*
D001095:Arachidonic Acids; D013189:SRS-A; D013931:Thromboxanes; D013928:Thromboxane A2; D006493:Heparin
Action hypotensive de l'acide arachidonique, substance à action lente de l'anaphylaxie (SRS-A) et thromboxane A2, chez le rat.