Virus-induced diabetes mellitus. V. Biological differences between the M variant and other strains of encephalomyocarditis virus.
The M variant of encephalomyocarditis virus is very closely related serologically to five other strains of encephalomyocarditis virus. Despite the serological relationship, these five viruses differ markedly from the M variant in their tissue tropisms and only the M variant infects beta cells of the pancreas, producing diabetes.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000209:etiology* / Q000276:immunology; D004686:Encephalomyocarditis virus / Q000276:immunology* / Q000472:pathogenicity*; D004769:Enterovirus Infections / Q000276:immunology*; D014644:Genetic Variation; D008297:Male; D051379:Mice; D009500:Neutralization Tests
D000914:Antibodies, Viral