Activity of liver fructose diphosphatase from chick embryos treated with aminoguanidine sulfate.
Injection of chick embryos with aminoguanidine sulfate (AGS) on the fourth day of incubation resulted in a decreased specific activity of liver fructose diphosphatase (FDPase) prior to hatch time. This decreased FDPase specific activity was found to be the consequence of increased levels of an enzyme inhibitor (adenosin 5'-monophosphate) rather than a specific repression of enzyme synthesis.
D000249:Adenosine Monophosphate / Q000494:pharmacology; D000588:Amines / Q000494:pharmacology; D000818:Animals; D002642:Chick Embryo / Q000187:drug effects / Q000201:enzymology*; D003956:Dialysis; D006597:Fructose-Bisphosphatase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006146:Guanidines / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000201:enzymology*
D000588:Amines; D006146:Guanidines; D000249:Adenosine Monophosphate; D006597:Fructose-Bisphosphatase