[Pulmonary function tests with the bronchodilator Terbutaline].
The acute bronchodilator effect of the beta 2-adrenoceptor agonist terbutaline was tested single-blind cross-over in out-patients with chronic obstructive airways disease (intrinsic asthma). In 7 series comparisons were made with other marketed bronchodilators. Airways resistance was measured by whole body plethysmography. In another 3 series the effect on heart rate of terbutaline and other adrenocepter agonists was tested in healthy volunteers. Terbutaline and the adrenoceptor agonists clenbuterol, epinephrine, fenoterol, hexoprenaline, isoprenaline, metaproterenol, reproterol and salbutamol, the vagolytics atropine, ipratropium bromide and AA 22-263, the xanthinederivative theophylline ethylenediamine and one combined substance drug were used.
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000420:Albuterol / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy*; D001285:Atropine / Q000627:therapeutic use; D002976:Clenbuterol / Q000627:therapeutic use; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D005280:Fenoterol / Q000627:therapeutic use; D006339:Heart Rate / Q000187:drug effects; D006594:Hexoprenaline / Q000627:therapeutic use; D006801:Humans; D007279:Injections, Subcutaneous; D009241:Ipratropium / Q000627:therapeutic use; D007545:Isoproterenol / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010276:Parasympatholytics / Q000627:therapeutic use; D013726:Terbutaline / Q000008:administration & dosage / Q000627:therapeutic use*; D013806:Theophylline / Q000627:therapeutic use
D010276:Parasympatholytics; D005280:Fenoterol; D001285:Atropine; D013806:Theophylline; D006594:Hexoprenaline; D009241:Ipratropium; D007545:Isoproterenol; D013726:Terbutaline; D000420:Albuterol; D002976:Clenbuterol; D004837:Epinephrine
Lungenfunktionsuntersuchungen mit dem Bronchospasmolytikum Terbutalin.