title: [Study of the organotropic and oncotropic properties of human type 16 adenovirus in the body of Syrian hamsters and mice (author's transl)].
abstract: Human adenovirus type 16 was studied in Syrian hamsters bearing SV40 virus induced transplantable tumour and in mice of Black line with Lewis cancer. Despite its tropism to the tumour tissue, the virus injected into the blood stream was first accumulated in the lung tissue and in organs of the  reticuloendothelial system (the spleen and liver). When the tumour was in the lung tissue of mice, the virus content in it was much higher than in a similar tumour of subcutaneous localization.
mesh_terms: D000256:Adenoviridae / Q000302:isolation & purification / Q000472:pathogenicity*; D000818:Animals; D001769:Blood / Q000382:microbiology; D001921:Brain / Q000382:microbiology; D002250:Carbon Radioisotopes; D002478:Cells, Cultured; D006224:Cricetinae; D006652:Histological Techniques; D007422:Intestines / Q000382:microbiology; D007668:Kidney / Q000382:microbiology; D008099:Liver / Q000382:microbiology; D008168:Lung / Q000382:microbiology; D008198:Lymph Nodes / Q000382:microbiology; D008748:Methylcholanthrene; D051379:Mice; D008815:Mice, Inbred Strains; D009132:Muscles / Q000382:microbiology; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000382:microbiology; D013539:Simian virus 40; D013154:Spleen / Q000382:microbiology; D013997:Time Factors; D014316:Tritium; D014776:Virus Cultivation; D014780:Viruses / Q000302:isolation & purification
chemical_list: D002250:Carbon Radioisotopes; D014316:Tritium; D008748:Methylcholanthrene
vernacular_title: Izuchenie organotrophnykh i onkotropnykh i onkotrophnykh svoĭstv chelovecheskogo adenovirusa tipa 16 v organizme siriĭskikh khomiachkov i mysheĭ