title: [Phototoxic reactions to 8-methoxypsoralen as occupational dermatosis].
abstract: The case history of a 50-year-old assistant pharmacist, who had been working with 8-methoxypsoralene (8-MOP) without any protection, is discussed. Shortly after this work, he was exposed to sunlight. Within 72 h he developed a typical local reaction with painful erythema and vesiculation on the back of both hands, followed by hyperpigmentation a week later. Light testing on skin dusted with 8-MOP resulted in the same clinical picture. Histopathological examination of a lesion showed the characteristics of a phototoxic dermatitis. Guidelines for the prevention of complications in those who are professionally exposed to 8-MOP are emphasized.
mesh_terms: D003877:Dermatitis, Contact / Q000209:etiology; D009783:Dermatitis, Occupational / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008730:Methoxsalen / Q000009:adverse effects*; D008875:Middle Aged; D009790:Occupations; D010604:Pharmacy; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D011481:Protective Clothing
chemical_list: D008730:Methoxsalen
vernacular_title: Phototoxische Reaktion auf 8-Methoxypsoralen als Berufsdermatose.