[The mode of action of bacteriocin N5 purified from Clostridium perfringens].
The purified bacteriocin N5 produced by Clostridium perfringens BP6K inhibited simultaneously the syntheses of DNA, RNA and protein in sensitive cells, without DNA degradation. Bacteriocin N5 inhibited the accumulation of leucin and caused the exit of the previously accumulated amino acid. The effects of bacteriocin N5 are very similar to those observed for colicins E1, K, A and I.
D001426:Bacterial Proteins / Q000096:biosynthesis; D001430:Bacteriocins / Q000494:pharmacology*; D001693:Biological Transport, Active / Q000187:drug effects; D003016:Clostridium perfringens / Q000187:drug effects* / Q000378:metabolism; D004269:DNA, Bacterial / Q000096:biosynthesis; D007930:Leucine / Q000378:metabolism; D012329:RNA, Bacterial / Q000096:biosynthesis; D013997:Time Factors
D001426:Bacterial Proteins; D001430:Bacteriocins; D004269:DNA, Bacterial; D012329:RNA, Bacterial; D007930:Leucine
Sur le mode d'action de la bactériocine N5 purifiée de Clostridium perfringens