Placental barrier against circulating immune complexes. A study in pregnant guinea pigs using maternal injection of horseradish peroxidase soluble immune complexes.
It is not rare that the so-called immune complex diseases (some of which were recently supposed to be induced by the biological effects of circulating antigen-antibody immune complexes) are concomitantly present in pregnant females. But there have been very few reports of congenital immune complex diseases.
D000818:Animals; D000936:Antigen-Antibody Complex; D005260:Female; D005455:Fluorescent Antibody Technique; D006168:Guinea Pigs; D007105:Immune Complex Diseases / Q000151:congenital* / Q000196:embryology; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000378:metabolism; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000378:metabolism; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology
D000936:Antigen-Antibody Complex; D007074:Immunoglobulin G