Relation between fibrinolytic activity and prostacyclin generation of atherosclerotic artery and dacron prosthetic graft.
The newly formed tissue of dacron vascular prosthetic grafts implanted in humans demonstrates prostacyclin generation and fibrinolytic activity comparable to that of the atherosclerotic artery in the vicinity. This provides some evidence that both activities important for haemostasis run parallel.
D000368:Aged; D001158:Arteries; D001161:Arteriosclerosis / Q000503:physiopathology*; D004727:Endothelium / Q000503:physiopathology; D011464:Epoprostenol / Q000378:metabolism*; D005342:Fibrinolysis / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates / Q000494:pharmacology*; D011453:Prostaglandins / Q000378:metabolism*; D019736:Prostheses and Implants / Q000009:adverse effects
D011093:Polyethylene Terephthalates; D011453:Prostaglandins; D011464:Epoprostenol