title: Some aspects of ACTH action on cerebral metabolism in infant rats.
abstract: In 150 newborn rats of either sex the influence of ACTH on cerebral phospholipid, phosphoprotein, and nucleic acids metabolism was investigated. The results show that ACTH induces a great stimulation of the cerebral phospholipid metabolism, especially in 14-and 21-day-old rats, a significant increase in the phosphoprotein metabolism at 7 and 14 days after birth, and a stimulation of the RNA synthesis in 7- and 14-day-old rats. The significance of these results is discussed.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000367:Age Factors; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D004247:DNA / Q000096:biosynthesis*; D005260:Female; D008297:Male; D010743:Phospholipids / Q000378:metabolism*; D010750:Phosphoproteins / Q000378:metabolism*; D012313:RNA / Q000096:biosynthesis*; D051381:Rats
chemical_list: D010743:Phospholipids; D010750:Phosphoproteins; D012313:RNA; D000324:Adrenocorticotropic Hormone; D004247:DNA