Stress polycythemia--a pathophysiologic study.
Two patients with "Gaisböck syndrome" (stress polycythemia) were found to have been under chronic "stress" with REM sleep decrease, decreased nocturnal ADH-like activity and consequent nocturnal water loss. The role of REM decrease with chronic "stress" in causing secondary decrease in nocturnal ADH-like activity was emphasized as the means by which "stress" caused the blood volume changes seen with these two patients. Some factors that possibly could play a role in the pathophysiology of this syndrome were ruled out and other factors not studied here were considered for future investigation.
D015065:17-Hydroxycorticosteroids / Q000378:metabolism; D000328:Adult; D001794:Blood Pressure; D002940:Circadian Rhythm; D004912:Erythrocytes; D006400:Hematocrit; D006632:Histamine / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008676:Metanephrine / Q000652:urine; D009647:Normetanephrine / Q000652:urine; D010953:Plasma Volume; D011086:Polycythemia / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology*; D011674:Pulse; D012895:Sleep, REM; D012964:Sodium / Q000652:urine; D013046:Specific Gravity; D013315:Stress, Psychological; D013577:Syndrome
D015065:17-Hydroxycorticosteroids; D009647:Normetanephrine; D008676:Metanephrine; D006632:Histamine; D012964:Sodium; D006854:Hydrocortisone