Extracellular Ca2+ and Mg2+ and cellular metabolism of phospholipids.
High extracellular concentration of Ca2+ inhibits the incorporation of 32P into the cellular phospholipids. This effect is more significant in neoplastic than in normal cells, and it is accompanied by an increase of the percentual incorporation into the lecithin fraction.
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D002118:Calcium / Q000378:metabolism / Q000494:pharmacology*; D006528:Carcinoma, Hepatocellular / Q000378:metabolism; D005110:Extracellular Space / Q000032:analysis; D066298:In Vitro Techniques; D007424:Intracellular Fluid / Q000032:analysis; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008113:Liver Neoplasms; D008274:Magnesium / Q000494:pharmacology*; D010743:Phospholipids / Q000096:biosynthesis*; D010758:Phosphorus / Q000378:metabolism; D051381:Rats
D010743:Phospholipids; D010758:Phosphorus; D008274:Magnesium; D002118:Calcium