Regulation of lactate dehydrogenase activity in Rothia dentocariosa by fructose 1,6-diphosphate and adenosine 5'-triphosphate.
The L-(+)-lactate dehydrogenase from Rothia dentocariosa strain 17931 is activated by fructose 1,6-diphosphate and inhibited by adenosine 5'-triphosphate. The enzyme has a molecular weight of 120,000. In these respects, it resembles the lactate dehydrogenase of Actinomyces viscosus.
D000191:Actinomycetaceae / Q000201:enzymology*; D000255:Adenosine Triphosphate / Q000494:pharmacology*; D002474:Cell-Free System; D004789:Enzyme Activation / Q000187:drug effects; D005636:Fructosephosphates / Q000494:pharmacology*; D007770:L-Lactate Dehydrogenase / Q000032:analysis / Q000378:metabolism*; D007773:Lactates / Q000096:biosynthesis; D008970:Molecular Weight; D009243:NAD / Q000378:metabolism; D011773:Pyruvates / Q000378:metabolism
D005636:Fructosephosphates; D007773:Lactates; D011773:Pyruvates; D009243:NAD; D000255:Adenosine Triphosphate; D007770:L-Lactate Dehydrogenase