Studies on the interference between the allergic reactions caused by different antigen-antibody systems.
Interference between two different in vivo antigen-antibody reactions which occurred simultaneously was studied in guinea pigs. Animals were presensitized with an aqueous fraction (CP) extracted from cells of Corynebacterium equi, strain KO-85. Skin reactions of the Arthus type elicited by the CP fraction inhibited passive cutaneous anaphylaxis (PCA) induced by bovine serum albumin (BSA) and rabbit anti-BSA serum. PCA reactions of the CP-sensitized animals were also inhibited upon simultaneous challenges of BSA and the CP as evidence by reduction of PCA titer of the anti-BSA serum.
D000818:Animals; D000906:Antibodies; D000937:Antigen-Antibody Reactions; D000941:Antigens; D001183:Arthus Reaction / Q000276:immunology*; D003352:Corynebacterium / Q000276:immunology; D006168:Guinea Pigs; D008297:Male; D010323:Passive Cutaneous Anaphylaxis; D012710:Serum Albumin, Bovine / Q000276:immunology
D000906:Antibodies; D000941:Antigens; D012710:Serum Albumin, Bovine