title: On the mechanism of tolerance to isoproterenol-induced accumulation of cAMP in rat pineal in vivo.
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000378:metabolism; D000262:Adenylyl Cyclases / Q000378:metabolism; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D004361:Drug Tolerance; D007545:Isoproterenol / Q000494:pharmacology*; D008297:Male; D010870:Pineal Gland / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D051381:Rats
chemical_list: D000242:Cyclic AMP; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D000262:Adenylyl Cyclases; D007545:Isoproterenol