Neurological complication of antirabies vaccination in São Paulo, Brazil. Clinical and therapeutical aspects.
The author studied especially the clinical aspects and therapeutic results in 73 patients with neurological complication of anti-rabies vaccination. The neuroparalytic accidents and the most constant neurologic signs and symptoms were emphasized. The most common clinical syndrome was thoraco-lumbar meningomyelitis and there were CSF alterations in 88% of the cases studied. Eighteen patients presented neurologic complications after Fuenzalida vaccine: only 1 of them had Guillain-Barré syndrome, 1 had meningoradiculitis, 4 had myelitis and in the other 12 cases there was diffuse involvement of the nervous system especially of the spinal cord and meninges (meningomyelitis and meningoencephalomyelitis).
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use*; D000328:Adult; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007249:Inflammation; D007278:Injections, Spinal; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009422:Nervous System Diseases / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000209:etiology*; D010243:Paralysis / Q000209:etiology*; D011818:Rabies / Q000517:prevention & control; D011819:Rabies Vaccines / Q000009:adverse effects*; D014611:Vaccination
D000305:Adrenal Cortex Hormones; D011819:Rabies Vaccines; D000324:Adrenocorticotropic Hormone; D008775:Methylprednisolone