title: External and interstitial radiation therapy of carcinoma of the oral tongue. A review of 32 years' experience.
abstract: In 204 patients with squamous cell carcinoma of the oral tongue treated with radiation therapy, the most significant prognostic factors appeared to be the presence of neck lymph node metastasis on presentation and the status of the disease three months after treatment. The most common site of failure was the primary lesion, either alone or with neck disease. External irradiation alone was seldom successful. Use of peroral cone irradiation or interstitial implants, either alone or in combination with external irradiation, achieved good local control in early lesions. When the primary tumor was uncontrolled by radiation therapy, salvage with surgery was rare. When failure occurred in the neck alone, radical neck dissection was successful in the majority of cases.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001847:Bone Diseases / Q000209:etiology; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000532:radiotherapy*; D005260:Female; D006258:Head and Neck Neoplasms / Q000401:mortality / Q000532:radiotherapy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D009378:Neoplasms, Multiple Primary; D011379:Prognosis; D011832:Radiation Injuries; D011882:Radiotherapy, High-Energy; D011883:Radium / Q000008:administration & dosage; D011886:Radon / Q000008:administration & dosage; D012142:Respiratory Tract Neoplasms / Q000175:diagnosis; D014062:Tongue Neoplasms / Q000401:mortality / Q000532:radiotherapy*
chemical_list: D011886:Radon; D011883:Radium