Latent herpetic infections following experimental viraemia.
The spectrum of tissues harbouring latent herpes simplex virus following intravenous inoculation of mice was defined by in vitro co-cultivation techniques. The virus could be detected in central and peripheral nervous systems (including adrenal medulla), but could not be found in any non-neural tissues. Spinal ganglia were the organs most commonly involved. The relationship of these findings to the natural history of herpetic infections is discussed.
D000311:Adrenal Glands / Q000382:microbiology; D000818:Animals; D001769:Blood / Q000382:microbiology; D001921:Brain / Q000382:microbiology; D005727:Ganglia, Spinal / Q000382:microbiology; D006561:Herpes Simplex / Q000382:microbiology*; D051379:Mice; D018139:Simplexvirus / Q000254:growth & development* / Q000302:isolation & purification; D013116:Spinal Cord / Q000382:microbiology