Hepatoma occurring two decades after hepatic irradiation.
Hepatoma has been related to chemical, dietary, metabolic, infectious, and genetic factors. therapeutic hepatic irradiation has never been associated with hepatoma. A case of hepatocellular carcinoma is presented that occurred two decades after radiotherapy for presumed hepatic hemangioma. Radiation-related liver disease is discussed in general, with emphasis placed on radiation hepatocarcinogenesis.
D002252:Carbon Tetrachloride Poisoning / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000209:etiology* / Q000473:pathology; D002648:Child; D004247:DNA / Q000378:metabolism; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology* / Q000473:pathology; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D011878:Radiotherapy / Q000009:adverse effects*; D013997:Time Factors
D004247:DNA