Efficacy of phosphonoacetic acid on herpes simplex virus infection of sensory ganglia.
Treatment of mice with phosphonoacetic acid markedly reduced the incidence of latent ganglionic infection with herpes simplex virus when administered within 24 h after viral inoculation, but had no effect on an already established ganglionic infection.
D000085:Acetates / Q000627:therapeutic use*; D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use; D005260:Female; D005724:Ganglia / Q000382:microbiology*; D006561:Herpes Simplex / Q000188:drug therapy*; D051379:Mice; D008807:Mice, Inbred BALB C; D009422:Nervous System Diseases / Q000188:drug therapy; D009943:Organophosphorus Compounds / Q000627:therapeutic use*; D018139:Simplexvirus / Q000472:pathogenicity*
D000085:Acetates; D000998:Antiviral Agents; D009943:Organophosphorus Compounds