A case of acromegaly improved by pituitary apoplexy.
This report deals with a detailed course of one patient with acromegaly who had a pituitary apoplexy.  The pituitary apoplexy occurred suddenly 5 days after administration of a oral hypoglycemic agent, buformin, during hospitalization.  Immediately after the attack changes of the concentrations of several hormones such as serum growth-hormone, serum thyroid hormone and urinary 17-hydroxycorticosteroids were followed until the development to hypopituitary state.  Simultaneously with the decrease of the concentrations of the above-mentioned hormones, a regression of the physical manifestations of acromegaly and a complete amelioration of diabetes mellitus were observed.
D015065:17-Hydroxycorticosteroids / Q000652:urine; D000172:Acromegaly / Q000150:complications / Q000503:physiopathology*; D000324:Adrenocorticotropic Hormone / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D008875:Middle Aged; D010900:Pituitary Diseases / Q000150:complications / Q000503:physiopathology*; D012075:Remission, Spontaneous / Q000097:blood; D013963:Thyroid Hormones / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone
D015065:17-Hydroxycorticosteroids; D001786:Blood Glucose; D007328:Insulin; D013963:Thyroid Hormones; D013973:Thyrotropin-Releasing Hormone; D000324:Adrenocorticotropic Hormone; D013972:Thyrotropin; D013006:Growth Hormone