Mechanism of induction of gastrointestinal toxicity in the mouse by 5-fluorouracil, 5-fluorouridine, and 5-fluoro-2'-deoxyuridine.
D000818:Animals; D001835:Body Weight; D004064:Digestive System / Q000187:drug effects* / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005467:Floxuridine / Q000378:metabolism / Q000633:toxicity*; D005472:Fluorouracil / Q000378:metabolism / Q000633:toxicity*; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D012313:RNA / Q000096:biosynthesis; D013997:Time Factors; D014529:Uridine / Q000031:analogs & derivatives* / Q000378:metabolism
D005467:Floxuridine; D012313:RNA; D005472:Fluorouracil; D014529:Uridine