Central functional changes after facial-spinal-accessory anastomosis in man and facial-hypoglossal anastomosis in the cat.
A left facial-spinal-accessory anastomosis was performed for peripheral facial paralysis in an 8-year-old boy. By the fourth postoperative year, the corneal reflex showed a normal latency, and left arm and face movements could be executed independently. The possibility of neural plasticity playing a role in establishing new central relationships which enable the achievement of a "normal" latency corneal reflex and independent face and arm movements is discussed. The latency of the corneal reflex recorded as electrical response of the orbicularis oculi muscle to electrical stimulation of the ipsilateral cornea was measured in normal cats and cats which had undergone a facial-hypoglossal anastomosis 12 to 14 months previously. The latency of the reflex was 8 to 22 msec in normal animals and 200 to 300 msec in the operated cats, while conduction times in the regenerated hypoglossal nerve fibers were found to be within normal limits. This suggests that the long latency of the corneal reflex following the cross anastomosis is due to the time required for transmission across newly-formed connections between the trigeminal terminals and the hypoglossal neurons.
D000055:Accessory Nerve / Q000601:surgery; D000818:Animals; D002415:Cats; D002648:Child; D004558:Electric Stimulation; D004576:Electromyography; D005154:Facial Nerve / Q000601:surgery; D005158:Facial Paralysis / Q000601:surgery*; D000882:Haplorhini; D006801:Humans; D007002:Hypoglossal Nerve / Q000601:surgery; D008297:Male; D009470:Muscle Spindles / Q000601:surgery; D009416:Nerve Regeneration; D009431:Neural Conduction; D009434:Neural Pathways / Q000601:surgery*; D019635:Neurosurgical Procedures; D009801:Oculomotor Muscles / Q000294:innervation; D010523:Peripheral Nervous System Diseases / Q000601:surgery*; D012025:Reflex, Pupillary; D012032:Refractory Period, Electrophysiological; D009435:Synaptic Transmission