title: Molecular structures of cytidine-5'-diphosphate and cytidine-5'-diphospho-choline, and their role in intermidiary metabolism.
abstract: The nucleotide coenzyme cytidine-5'-diphospho-choline is highly folded. The CMP-5' parts of the molecules in the crystal structure are strongly linked by metal ligation and hydrogen bonds leaving the phosphoryl-choline residues relatively free. Cytidine-5'-diphosphoric acid exists as a zwitterion with N31 protonated. The P-O bond lengths from the anhydride bridging oxygen in the pyrophosphate are significantly different.
mesh_terms: D002794:Choline / Q000031:analogs & derivatives*; D003566:Cytidine Diphosphate Choline / Q000378:metabolism; D003597:Cytosine Nucleotides / Q000378:metabolism; D011756:Diphosphates; D008958:Models, Molecular
chemical_list: D003597:Cytosine Nucleotides; D011756:Diphosphates; D003566:Cytidine Diphosphate Choline; D002794:Choline