title: Functional possibilities for aminoacylation of viral RNA in transcription and translation.
abstract: RNA from at least ten viruses, representing more than four different group, is known to specifically bind in amino acid in a tRNA-like manner. The biological function of aminoacylation of RNA from these viruses and of tRNA association with tumor viruses and bacteriophage, is discussed. Hypothetical schemes are presented for a role for aminoacylation in viral translational and transcriptional mechanisms, and the current evidence relating to these models is presented.
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D009189:Avian Myeloblastosis Virus / Q000378:metabolism; D001358:Avian Sarcoma Viruses / Q000378:metabolism; D003090:Coliphages / Q000378:metabolism; D007700:Kinetics; D009029:Mosaic Viruses / Q000378:metabolism; D010452:Peptide Biosynthesis; D010942:Plant Viruses / Q000378:metabolism*; D014176:Protein Biosynthesis; D012343:RNA, Transfer / Q000378:metabolism; D012367:RNA, Viral / Q000378:metabolism*; D013698:Templates, Genetic; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000096:biosynthesis; D014779:Virus Replication
chemical_list: D000596:Amino Acids; D012367:RNA, Viral; D014764:Viral Proteins; D012343:RNA, Transfer