Temperature sensitivity of cyclic adenosine 3':5'-monophosphate-binding proteins and the regulation of growth and differentiation in neuroblastoma cells.
The apparent association constant (K-a) of cAMP to the binding proteins from resistant and nonresistant cells was 7.4 times 10-7 M-1 and 8.2 times 10-7 M-1, respectively, and the specific activity of cAMP BINDING TO THESE PROTEINS WAS SIMILAR FOR BOTH TYPES OF CELLS.
D000109:Acetylcholine; D000110:Acetylcholinesterase / Q000378:metabolism; D000628:Aminophylline / Q000494:pharmacology; D000818:Animals; D001369:Axons / Q000254:growth & development; D003994:Bucladesine / Q000494:pharmacology; D002454:Cell Differentiation / Q000187:drug effects; D002478:Cells, Cultured; D000242:Cyclic AMP / Q000378:metabolism*; D004228:Dithionitrobenzoic Acid / Q000494:pharmacology; D007700:Kinetics; D008623:Mercaptoethanol / Q000494:pharmacology; D051379:Mice; D009447:Neuroblastoma / Q000378:metabolism*; D011458:Prostaglandins E / Q000494:pharmacology; D011485:Protein Binding; D011955:Receptors, Drug; D013696:Temperature
D011458:Prostaglandins E; D011955:Receptors, Drug; D000628:Aminophylline; D008623:Mercaptoethanol; D003994:Bucladesine; D004228:Dithionitrobenzoic Acid; D000242:Cyclic AMP; D000110:Acetylcholinesterase; D000109:Acetylcholine