[Neonatal hypoglycemia due to hyperinsulinism secondary to Langerhans' polyadenomatosis. Recovery after pancreatectomy].
Report of a case of a neonatal hypoglycemia detected at the 11th hour of life, secondary to a Langherans polyadenomatosis in a girl with an hemihypertrophy. Pre- and post-operative tests are reported. In case of neonatal hypoglycemia, the criteria leading to the diagnosis of hyperinsulinism, i.e. the only neonatal hypoglycemia with surgical treatment are reviewed. Except in the case of adenoma, the pancreatectomy should be performed subtotally. The best time for surgery is as soon as the 3rd week, in order to preserve the cerebral development.
D007516:Adenoma, Islet Cell / Q000150:complications*; D001786:Blood Glucose / Q000378:metabolism; D003981:Diazoxide / Q000627:therapeutic use; D005260:Female; D005934:Glucagon / Q000032:analysis; D005947:Glucose / Q000008:administration & dosage; D005949:Glucose Oxidase / Q000032:analysis; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D006943:Hyperglycemia / Q000139:chemically induced; D006946:Hyperinsulinism / Q000150:complications* / Q000209:etiology; D007003:Hypoglycemia / Q000209:etiology* / Q000601:surgery; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology*; D007328:Insulin / Q000032:analysis; D007515:Islets of Langerhans / Q000473:pathology; D007930:Leucine / Q000032:analysis; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000150:complications*; D011863:Radioimmunoassay
D001786:Blood Glucose; D007328:Insulin; D005934:Glucagon; D005949:Glucose Oxidase; D007930:Leucine; D005947:Glucose; D003981:Diazoxide; D006854:Hydrocortisone
Hypoglycemie neonatale par hyperinsulinisme secondaire a une polyadenomatose Langheransienne. Pancreatectomie suivie de guerison