Hydatidiform mole metastasizing to the lung.
Pulmonary lesions developed in three patients with an invasive hydatidiform mole. At open thoracotomy the modules were found to contain molar tissue. Therapy with twice-weekly methotrexate induced complete clinical and biologic remission of the disease in all three patients.
D000293:Adolescent; D000328:Adult; D006063:Chorionic Gonadotropin / Q000652:urine; D005260:Female; D006801:Humans; D002820:Hydatidiform Mole, Invasive / Q000188:drug therapy / Q000473:pathology* / Q000652:urine; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology*; D008727:Methotrexate / Q000627:therapeutic use; D009215:Myometrium / Q000473:pathology; D009362:Neoplasm Metastasis / Q000473:pathology*; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000473:pathology*
D006063:Chorionic Gonadotropin; D008727:Methotrexate