Heat sensitivity of murine sarcoma virus.
Murine sarcoma virus (Moloney) was found to be heat labile. Inactivation curve represents a first-order kinetics at temperatures between 30 degrees and 60 degrees. Inactivation constant analysis showed an inflexion at about 45 degrees, and the activation energy was calculated as 67.6 kcal/mol for higher temperature range and 7.95 kcal/mol for lower temperature range. Nature of inactivation is also discussed.
D003470:Culture Media; D017988:Gammaretrovirus / Q000472:pathogenicity*; D006358:Hot Temperature; D008979:Moloney murine leukemia virus / Q000472:pathogenicity*; D009053:Sarcoma Viruses, Murine / Q000472:pathogenicity*
D003470:Culture Media