Indirect EPR evidence for the production of singlet oxygen in the photosensitization of nucleic acid constituents by proflavine.
EPR spectroscopy is used to analyse the influence of D2O and NaN3 on the free radicals induced in frozen aqueous solutions of 5'-thymidine monophosphate photosensitized (lambda greater than 320 nm) by proflavine at 205 K. The results can be explained if the production of singlet oxygen during the process is assumed.
D000166:Acridines; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D008027:Light; D010084:Oxidation-Reduction; D010100:Oxygen; D010777:Photochemistry; D011370:Proflavine; D013942:Thymine Nucleotides
D000166:Acridines; D005609:Free Radicals; D013942:Thymine Nucleotides; D011370:Proflavine; D010100:Oxygen