Morphological observations of dysplastic gliomas heterotransplanted to experimental animals.
Observations concerning transplantation of 5 cases of malignant dysplastic gliomas to the anterior chamber of the guinea-pig eye have been presented. This type of gliomas, composed mainly of cytoplasm-abundant cells, show weak transplantability, slow rate of growth, and particular tendency to degeneration and necrosis. At the same time, in subsequent passages, an intensive proliferation of small-cell component occurs, comparing with cytoplasm-abundant cells.
D000818:Animals; D000867:Anterior Chamber / Q000601:surgery; D002455:Cell Division; D002470:Cell Survival; D046508:Culture Techniques; D005134:Eye Neoplasms / Q000473:pathology; D005909:Glioblastoma / Q000473:pathology; D005910:Glioma / Q000473:pathology*; D006168:Guinea Pigs; D006801:Humans; D007108:Immune Tolerance; D009336:Necrosis; D009368:Neoplasm Transplantation; D013997:Time Factors; D014183:Transplantation, Heterologous