Detection of T-cell surface determinants in three Marek's disease lymphoblastoid cell lines.
The T-cell surface antigens on three lymphoblastoid cell lines, MOB1, MOB-2 and MSB-1, derived from Marek's disease lymphomas were examined by the cytotoxicity test and the indirect membrane immunofluorescent test. These cell lines reacted specifically with antisera prepared against chicken thymus cells, although their reactivities were less than that of typical thymus cells. These three cell lines were of thymus origin.
D000818:Animals; D000941:Antigens; D000961:Antilymphocyte Serum / Q000494:pharmacology; D001354:Avian Leukosis Virus / Q000276:immunology; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology; D002645:Chickens; D003601:Cytotoxicity Tests, Immunologic; D005455:Fluorescent Antibody Technique; D008381:Herpesvirus 2, Gallid / Q000276:immunology; D008223:Lymphoma / Q000276:immunology; D008380:Marek Disease / Q000276:immunology*; D011817:Rabbits; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*
D000941:Antigens; D000961:Antilymphocyte Serum