Serological analysis of an oncornavirus (PMF virus) detected in malignant permanent human cell lines.
Immunodiffusion analysis of the PMF virus which was detected in malignant permanent human cell lines revealed positive reactions with antisera against the Mason-Pfizer monkey virus (MPMV). No cross-reactivity was demonstrated with murine leukemia virus (MuLV), rat leukemia virus (RaLV), hamster leukemia virus (HaLV), feline leukemia virus (FeLV), simian (woolly monkey) sarcoma virus (SSV-1) and mouse mammary tumor virus (MTV). The cross-reactive antigens of the PMF virus and the MPMV are considered as evidence for the human origin of the PMF virus.
D000818:Animals; D002417:Cattle; D002460:Cell Line / Q000276:immunology*; D006224:Cricetinae; D003429:Cross Reactions; D000882:Haplorhini; D006801:Humans; D005779:Immunodiffusion; D009052:Leukemia Virus, Murine / Q000276:immunology; D051379:Mice; D009858:Oncogenic Viruses / Q000276:immunology*; D051381:Rats; D013045:Species Specificity