Murine leukaemia virus expression in the AKR following thymectomy.
Thymectomy effectively prevents the development of spontaneous lymphoma in the AKR but how this effect is achieved remains to be determined. One possible mechanism, namely suppression of genomic expression of the oncogenic murine leukaemia virus now seems unlikely since levels of the group specific MuLV antigen were in comparision with their sham operated controls unaltered in both neonatally and adult thymectomized AKR.
D000367:Age Factors; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D007668:Kidney / Q000276:immunology; D009052:Leukemia Virus, Murine / Q000276:immunology*; D008099:Liver / Q000276:immunology; D008223:Lymphoma / Q000209:etiology; D051379:Mice; D008806:Mice, Inbred AKR; D013154:Spleen / Q000276:immunology; D013934:Thymectomy
D000956:Antigens, Viral