[Relation between urinary cyclic AMP, PTH and histomorphometric resorption parameter. A study of 44 human iliac crest bone biopsies].
Daily urinary cyclic AMP (AMPcU) has been compared to pth plasma level and to bone resorption parameters in 44 cases of metabolic bone disease. In 14 cases of primary hyperparathyroidism, AMPcU was always increased likewise in 4 cases of osteomalacia with secondary hyperparathyroidism. On the whole series of cases a significant correlation has been found (1) between PTH plasma level and AMPcU and (2) between bone resporption surfaces and AMPcU. Conversely, no correlation between PTH and periosteocytic lacunae size, nor between AMPcU and periosteocytic lacunae has been found.
D000236:Adenoma / Q000378:metabolism; D000328:Adult; D000368:Aged; D001862:Bone Resorption / Q000378:metabolism*; D001842:Bone and Bones / Q000648:ultrastructure; D002277:Carcinoma / Q000378:metabolism; D003404:Creatinine / Q000652:urine; D000242:Cyclic AMP / Q000652:urine*; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000378:metabolism; D006962:Hyperparathyroidism, Secondary / Q000378:metabolism; D006965:Hyperplasia / Q000378:metabolism; D007085:Ilium / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010018:Osteomalacia / Q000378:metabolism; D010024:Osteoporosis / Q000378:metabolism; D010279:Parathyroid Diseases / Q000378:metabolism; D010281:Parathyroid Hormone / Q000097:blood*; D010282:Parathyroid Neoplasms / Q000378:metabolism; D013223:Statistics as Topic
D010281:Parathyroid Hormone; D003404:Creatinine; D000242:Cyclic AMP
L'amp cyclique urinaire et la parathormone plasmatique confrontés aux paramètres histomorphométriques osseux de résorption. a propos de 44 biopsies osseuses iliaques humaines