title: Carcinoma of the esophagus in Africans: establishment of a continuously growing cell line from a tumor specimen.
abstract: Biopsy material, from a patient with an esophageal carcinoma of a type occurring relatively frequently in Africans in some regions of Southern Africa, has been adapted to cell culture conditions and has developed into a continuously growing tumor cell line. The cells have a squamous pattern of growth which they maintain, without piling up, even in heavily confluent cultures.
mesh_terms: D000261:Adenoviruses, Simian; D000349:Africa; D002460:Cell Line; D002478:Cells, Cultured / Q000201:enzymology / Q000648:ultrastructure; D003588:Cytopathogenic Effect, Viral; D004847:Epithelial Cells; D004848:Epithelium / Q000201:enzymology / Q000648:ultrastructure; D004938:Esophageal Neoplasms; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D018139:Simplexvirus
chemical_list: D005954:Glucosephosphate Dehydrogenase