title: Twelve years experience in establishing larger colonies of small laboratory animals under SPF conditions by means of germfree technology.
abstract: The special procedures and techniques to develop poly-associated gnotobiotic animals in order to start large SPF colonies of small laboratory animals are discussed.
mesh_terms: D000822:Animal Husbandry / Q000592:standards; D000818:Animals; D000830:Animals, Laboratory; D004064:Digestive System / Q000382:microbiology; D005260:Female; D005856:Germ-Free Life; D006168:Guinea Pigs; D007044:Hysterectomy / Q000662:veterinary; D051379:Mice; D011247:Pregnancy; D011270:Pregnancy, Animal; D011817:Rabbits; D051381:Rats; D013047:Specific Pathogen-Free Organisms