Secificity of mouse endocervical cell response progesterone: presence of receptors.
The mouse cervical cell response to progesterone, corticosterone, and androgens was studied in vitro and comparatively by grafts on males. Contrary to the exocervical cells which responded more or less to the three steroid hormones, the endocervical cells responded exclusively to progesterone even in an estrogen free system. This result suggests the existence in the mouse endocervical cells of specific receptors to progesterone and indicates that the squamons cells of the uterine cervix have a different response to steroid hormones depending on where these cells are located.
D000728:Androgens / Q000494:pharmacology; D000818:Animals; D002369:Castration; D002584:Cervix Uteri / Q000166:cytology / Q000187:drug effects* / Q000637:transplantation; D003345:Corticosterone / Q000494:pharmacology; D046508:Culture Techniques; D004971:Estrus; D005260:Female; D006025:Glycosaminoglycans / Q000096:biosynthesis; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D011247:Pregnancy; D011374:Progesterone / Q000494:pharmacology*; D011956:Receptors, Cell Surface; D014184:Transplantation, Homologous
D000728:Androgens; D006025:Glycosaminoglycans; D011956:Receptors, Cell Surface; D011374:Progesterone; D003345:Corticosterone
Spécificité de réponse des cellules de l'endocol de la souris à la progestérone: présence de récepteurs