Pyophosphate-induced inflammation: an in vivo study of the interrelationship of intracellular cyclic AMP and cyclic GMP.
The changes in leucocyte concentrations of cyclic AMP and cyclic GMP were monitored during pyrophosphate-induced pleurisy in rats. A classical 'Yin Yang' relationship was demonstrated.
D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D006152:Cyclic GMP / Q000378:metabolism*; D011756:Diphosphates / Q000494:pharmacology*; D007249:Inflammation / Q000139:chemically induced / Q000378:metabolism*; D008297:Male; D010998:Pleurisy / Q000139:chemically induced; D051381:Rats; D013997:Time Factors
D011756:Diphosphates; D000242:Cyclic AMP; D006152:Cyclic GMP