[Sensitivity of normal and Rous virus-transformed lines of Armenian hamster cells to infectious viruses].
The capacity of normal (NHET) and Rous virus-transformed cell line of armenian hamster both producing (SHET Sh-R) and not producing (SHET K-3) virus to support reproduction of vaccinia and Newcastle disease viruses was demonstrated. The former of these viruses replicated in the cell cultures with cytopathic effect, the latter did so without causing cell degeneration. The degree of Newcastle disease virus reproduction in all 3 cultures was the same whereas vaccinia virus synthesis in SHET Sh-R was inhibited as compared with NHET and SHET K-3 cultures. Interference between Rous virus and vaccinia virus in SHET Sh-R culture was not due to interferon. The infectious viruses under study caused no activation of Rous virus genome in the virogenic SHET K-3 cell line.
D000818:Animals; D001358:Avian Sarcoma Viruses / Q000254:growth & development; D002460:Cell Line; D006224:Cricetinae; D003588:Cytopathogenic Effect, Viral; D009522:Newcastle disease virus / Q000254:growth & development*; D014616:Vaccinia virus / Q000254:growth & development*; D014762:Viral Interference; D014779:Virus Replication
Chuvstvitel'nost' normal'noi i transformirovannoi virusom Rausa linii kletok armianskogo khomiachka k infektsionnym virusam