[Histoenzymatic changes and dosimetric studies of some organs and areas, using diagnostic radioisotopes. Critical review of a 10-year experiment].
Ten years experience of dosimetry and study of the histochemical changes brought on by internal irradiation are reviewed. The research is broken down into three stages: 1) identification of enzymatic damage in small laboratory animals; 2) study of the dose really absorbed at various points of critical organs of large animals, 3) the collection of histoenzymatic data resulting from research on large animals treated internally with isotopes commonly used in diagnosis.
D000118:Acetylglucosaminidase / Q000378:metabolism*; D000135:Acid Phosphatase / Q000378:metabolism*; D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D004285:Dogs; D006596:Hexosaminidases / Q000378:metabolism*; D007668:Kidney / Q000201:enzymology / Q000528:radiation effects*; D008099:Liver / Q000201:enzymology / Q000528:radiation effects*; D008247:Lysosomes / Q000201:enzymology / Q000528:radiation effects; D010088:Oxidoreductases / Q000378:metabolism*; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000201:enzymology*; D011868:Radioisotopes; D051381:Rats
D011868:Radioisotopes; D010088:Oxidoreductases; D000135:Acid Phosphatase; D006596:Hexosaminidases; D000118:Acetylglucosaminidase; D000251:Adenosine Triphosphatases
Modificazioni istoenzimatiche e rilievi dosimetrici su alcuni organi e distretti per impiego di radioisotopi a scopo diagnostico. Resoconto critico di una esperienza decennale.