[Quantitative determination of the epidermal G2-chalonelike factor in rat tissues by means of radial immunodiffusion].
A high-molecular glycoprotein (epidermal G2 chalone) shown to be homogeneous by electrophoresis and immunochemistry was isolated from rat skin. It exerts a strong tissue-rather than species-specific antimitotic effect on the keratinizing epithelium. The paper is concerned with its quantitative immunodiffusion determination in some tissues by means of monospecific antiserum. A clear-cut correlation between the mitotic index and the epidermal G2 chalone level in the mucosa is shown with special reference to vaginal epithelium of rats during the estrual cycle.
D000818:Animals; D004817:Epidermis / Q000032:analysis; D005260:Female; D006131:Growth Inhibitors / Q000032:analysis*; D005779:Immunodiffusion / Q000379:methods*; D007122:Immunoelectrophoresis / Q000379:methods; D008297:Male; D051381:Rats
D006131:Growth Inhibitors
Kolichestvennoe opredelenie v tkaniakh krys épidermal'nogo G2-keĭlonopodobnogo faktora metodom radioal'noĭ immunodiffuzii.