title: [State of the central regulation of glucocorticoid function of the adrenals in brain tumors].
abstract: Clinico-biochemical study of patients with tumours of the great hemispheres (75 observations) showed differences in the direction of reaction of the adrenal cortex to some actions. There was found a normal metopyron test, an inadequate activation in intensive stress action (an operation of removal of brain tumour) and a marked prolonged reaction to low stress stimulus (administration of low adrenaline doses). Several tests characterizing the function of negative reverse association mechanism and also reactions to stress actions of various intensity are necessary to assess the state of the central regulation of the glucocorticoid activity.
mesh_terms: D015065:17-Hydroxycorticosteroids / Q000097:blood; D000293:Adolescent; D000311:Adrenal Glands / Q000503:physiopathology*; D000324:Adrenocorticotropic Hormone; D000328:Adult; D001932:Brain Neoplasms / Q000503:physiopathology* / Q000601:surgery; D004837:Epinephrine; D005260:Female; D005938:Glucocorticoids / Q000502:physiology*; D006801:Humans; D008297:Male; D008797:Metyrapone; D008875:Middle Aged; D013312:Stress, Physiological / Q000503:physiopathology; D013997:Time Factors
chemical_list: D015065:17-Hydroxycorticosteroids; D005938:Glucocorticoids; D000324:Adrenocorticotropic Hormone; D004837:Epinephrine; D008797:Metyrapone
vernacular_title: O sostoianii tsentral'noĭ reguliatsii gliukokorikoidnoĭ funktsii nadpochechnikov pri opukholiakh golovnogo mozga