title: Cyclic adenosine 3':5'-monophosphate and inhibition of deoxyribonucleic acid synthesis in vitro.
abstract: Results are presented which suggest that inhibition of tritiated thymidine incorporation into the deoxyribonucleic acid of bone marrow in vitro by high concentrations of cyclic adenosine 3':5'-monophosphate is pharmacological in nature, and thus apparently unrelated to the physiological actions of cAMP.
mesh_terms: D000249:Adenosine Monophosphate / Q000494:pharmacology; D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000378:metabolism; D001854:Bone Marrow Cells; D003994:Bucladesine / Q000494:pharmacology; D002478:Cells, Cultured; D000242:Cyclic AMP / Q000494:pharmacology*; D006152:Cyclic GMP / Q000494:pharmacology; D004247:DNA / Q000096:biosynthesis*; D003841:Deoxycytidine / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013806:Theophylline / Q000494:pharmacology; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
chemical_list: D003841:Deoxycytidine; D014316:Tritium; D000249:Adenosine Monophosphate; D003994:Bucladesine; D004247:DNA; D013806:Theophylline; D000242:Cyclic AMP; D006152:Cyclic GMP; D013936:Thymidine