Effect of anti-mouse macrophage serum on murine cytomegalovirus infection.
Rabbit anti-mouse macrophage serum (AMS) was used to study the role played by macrophages against murine cytomegalovirus infection. Treatment of mice with AMS enhanced morbidity and mortality following virus infection. These results are discussed in relation to the role of macrophages against virus infections.
D000311:Adrenal Glands / Q000473:pathology; D000818:Animals; D003586:Cytomegalovirus Infections / Q000503:physiopathology*; D007106:Immune Sera / Q000494:pharmacology; D007372:Interferons / Q000097:blood; D007668:Kidney / Q000473:pathology; D008099:Liver / Q000473:pathology; D008214:Lymphocytes; D008264:Macrophages / Q000276:immunology / Q000503:physiopathology*; D051379:Mice; D010587:Phagocytosis; D013154:Spleen / Q000473:pathology
D007106:Immune Sera; D007372:Interferons