Cyclic nucleotide metabolism coupled to cytodifferentiation of Blastocladiella emersonii.
Cyclic GMP and cyclic AMP levels during growth and differentiation of B. emersonii were measured by use of chemical, biochemical, and immunologic assays. Of particular interest was the finding that net synthesis of cyclic GMP occurred during a single stage of its life cycle, sporulation, when intracellular levels increased 50- to 100-fold in a process requiring protein and RNA synthesis.
D001754:Blastocladiella / Q000254:growth & development / Q000378:metabolism*; D000242:Cyclic AMP / Q000378:metabolism*; D006152:Cyclic GMP / Q000378:metabolism*; D003513:Cycloheximide / Q000494:pharmacology; D003609:Dactinomycin / Q000494:pharmacology; D005658:Fungi / Q000378:metabolism*; D006868:Hydrolysis; D013172:Spores, Fungal / Q000378:metabolism
D003609:Dactinomycin; D003513:Cycloheximide; D000242:Cyclic AMP; D006152:Cyclic GMP