[Neurulation and interkinetic nuclear migration in the chick embryo (author's transl)].
Neurulation and interkinetic nuclear migration was studied in cells of the forming neural tube of chick embryos submitted to a variety of treatments. Our results show that cytochalasin B (5 mug/ml) does not protect microtubules against disruption occurring after 3 h at 2 degrees C nor does it prevent their repolymerization once they are cold-disrupted. However, db-cAMP protects microtubules against such cold disruption. We indicate that the inhibitory effect of cytochalasin B on interkinetic nuclear migration cannot be ascribed to an effect on microtubules.
D000818:Animals; D003994:Bucladesine / Q000494:pharmacology; D002465:Cell Movement; D002467:Cell Nucleus / Q000187:drug effects; D002642:Chick Embryo; D003080:Cold Temperature; D003571:Cytochalasin B / Q000494:pharmacology; D005724:Ganglia / Q000166:cytology; D007700:Kinetics; D008870:Microtubules / Q000187:drug effects; D009420:Nervous System / Q000196:embryology*
D003571:Cytochalasin B; D003994:Bucladesine
Neurulation et migration nucléaire intercinétique chez des embryons de poulet