title: Immunity to transmissible (coronaviral) enteritis of turkeys (bluecomb).
abstract: Turkey flocks recovering from natural and laboratory induced coronaviral enteritis developed lifelong immunity. Virus neutralization tests indicated that neutralization capacity of serums from recovered turkeys was low. One-way cross challenge test using turkeys inoculated with various bluecomb isolates revealed close antigenic relationship or antigenic identity among bluecomb isolates. The controlled application of intestinal preparations containing coronavirus as a vaccination procedure had value in developing active lasting immunity but it has limitations in areas that are attempting to eliminate the disease by a depopulation program. Killed vaccines injected parenterally did not produce a detectable immunity.
mesh_terms: D000818:Animals; D003332:Coronaviridae / Q000254:growth & development / Q000276:immunology; D004752:Coronavirus, Turkey; D004625:Embryo, Nonmammalian; D004751:Enteritis / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D005455:Fluorescent Antibody Technique; D007422:Intestines / Q000473:pathology; D009500:Neutralization Tests; D011201:Poultry Diseases / Q000276:immunology* / Q000473:pathology; D012087:Reoviridae; D012088:Reoviridae Infections / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D014422:Turkeys