title: [Early IgM decrease in the serum of carcinoma patients with paraneoplastic skin manifestations].
abstract: The authors describe two patients suffering from cancer accompanied with paraneoplastic skin disorders (bullous pemphigoid, dermatomyositis). Before the diagnosis of stomach cancer was obtained by X-ray examination, the IgM-level was found lower than in normal persons. The value of the IgM-estimation in the serum seems to be high in the diagnosis of tumours. Other causes of the decreased IgM-level than tumours and paraneoplastic disorders of the skin were not found.
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000276:immunology*; D002293:Adenocarcinoma, Scirrhous / Q000150:complications / Q000276:immunology*; D000368:Aged; D003882:Dermatomyositis / Q000209:etiology / Q000276:immunology; D006801:Humans; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000209:etiology / Q000276:immunology*; D012872:Skin Diseases, Vesiculobullous / Q000209:etiology / Q000276:immunology; D013274:Stomach Neoplasms / Q000150:complications / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Frühzeitige IgM-Verminderung im Serum von Karzinomkranken mit paraneoplastischen Hauterscheinungen