Mechanism of urea nitrogen binding by proposed oxidized starch gastrointestinal absorbents.
By use of 14-C label it was demonstrated that apparent binding of urea N to polyaldehyde starch was probably preceeded by hydrolysis to ammonium ion. Thus direct urea binding was not the mechanism through which ingested polyaldehyde starch might increase fecal N excretion in uremic patients.
D003485:Cyanates / Q000378:metabolism; D005243:Feces; D008024:Ligands; D009584:Nitrogen / Q000378:metabolism; D010504:Periodic Acid; D000644:Quaternary Ammonium Compounds / Q000378:metabolism; D013213:Starch / Q000494:pharmacology*; D014508:Urea / Q000378:metabolism*; D014511:Uremia / Q000188:drug therapy
D003485:Cyanates; D008024:Ligands; D000644:Quaternary Ammonium Compounds; D010504:Periodic Acid; D014508:Urea; D013213:Starch; D009584:Nitrogen