title: [The current state of masculine contraception].
abstract: The present state of male contraception is reviewed with reference to pharmacological methods only. Since spermatogenesis is the result of a long chain of endocrine mechanisms starting in the hypothalamus, any review of contraceptive techniques must follow these physiological links. Spermatogenesis itself involves different stages and each of them can be a target for pharmacological compounds. Although no drug is currently available that offers all the necessary guarantees required of a contraceptive, interesting interconnections have nevertheless emerged. In consequence there are grounds for moderate optimism as to the availability of a male contraceptive in the coming years.
mesh_terms: D000328:Adult; D000728:Androgens / Q000494:pharmacology; D000906:Antibodies; D003272:Contraceptive Agents, Male; D004822:Epididymis / Q000187:drug effects; D004967:Estrogens / Q000494:pharmacology; D005640:Follicle Stimulating Hormone; D006801:Humans; D007986:Luteinizing Hormone; D008297:Male; D009593:Nitroimidazoles / Q000494:pharmacology; D011374:Progesterone / Q000494:pharmacology; D013090:Spermatocytes / Q000187:drug effects; D013092:Spermatogenesis-Blocking Agents / Q000494:pharmacology; D013876:Thiophenes / Q000494:pharmacology
chemical_list: D000728:Androgens; D000906:Antibodies; D003272:Contraceptive Agents, Male; D004967:Estrogens; D009593:Nitroimidazoles; D013092:Spermatogenesis-Blocking Agents; D013876:Thiophenes; D011374:Progesterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
vernacular_title: Etat actuel de la contraception masculine