title: Villous adenomas of the colorectum.
abstract: During a ten-year period 258 patients with villous adenomas were seen at the Massachusetts General Hospital: seventy-four of these patients (29%) had invasive cancer that developed in adenomas. The operative mortality ascribed to removal of benign adenomas was zero, but for cancer arising in villous adenomas it was 3 per cent. Therapy often is difficult because of the size and location of the tumors. Methods of removal have been considered in detail.
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology; D000236:Adenoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D000368:Aged; D003082:Colectomy; D003106:Colon / Q000473:pathology; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D003125:Colostomy; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000473:pathology; D007417:Intestinal Polyps / Q000601:surgery; D007813:Laparotomy; D008297:Male; D009364:Neoplasm Recurrence, Local; D009928:Organ Specificity; D011183:Postoperative Complications / Q000401:mortality; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D012007:Rectum / Q000473:pathology; D012812:Sigmoidoscopy; D009626:Terminology as Topic