title: [Peptide-hydrolase activity in different areas of brain with introduction of hydrocortisone and ACTH].
abstract: A single introduction of hydrocortisone is established to evoke an increase in the total activity of acid peptide-hydrolase in most areas of the brain. A single administration of ACTH single and long term administration of hydrocortisone was found to increase the specific activity of acid peptide-hydrolase of the soluble fraction. The specific activity of neutral peptide-hydrolase of the soluble fraction increases with a single administration of ACTH and long term administration of hydrocortisone. A single and long term administration of hydrocortisone and ACTH cause an increase in the percentage of the soluble form of peptide-hydrolases of the total activity.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology*; D006854:Hydrocortisone / Q000494:pharmacology*; D009928:Organ Specificity; D010447:Peptide Hydrolases / Q000378:metabolism*
chemical_list: D000324:Adrenocorticotropic Hormone; D010447:Peptide Hydrolases; D006854:Hydrocortisone
vernacular_title: Peptyd-hidrolazna aktyvnist' u piznykh viddilakh holovnoho mozku za vvedennia hidrokortyzonu ĭ AKTH