Asthma due to non-occupational exposure to toluene (tolylene) di-isocyanate.
The production of asthma by toluene di-isocyanate, aspirated into the ventilating system and emanating from the exhausts of a neighbouring factory, was established in three otherwise non-exposed clerical workers. Occupational-type exposure tests with a polyurethane varnish/toluene di-isocyanate mixture elicited vigorous and prolonged non-immediate asthmatic reactions, thus enabling identification of the otherwise, obscure etiological cause of their asthma.
D000328:Adult; D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D001249:Asthma / Q000139:chemically induced* / Q000175:diagnosis; D003485:Cyanates / Q000506:poisoning*; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014051:Toluene 2,4-Diisocyanate / Q000506:poisoning*; D014691:Ventilation
D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D003485:Cyanates; D014051:Toluene 2,4-Diisocyanate