Radioactive ruthenium red accumulation by tumors: a potential scanning agent.
The distribution of 103-Ru-Ruthenium red in tumour bearing animals indicates that Ruthenium red labelled with radioruthenium shows the characteristics of a tumour scanning agent. Its accumulation seems to be related to its specific binding to mucopolysaccharides. In addition, this radiocompound shows a potential value in the study of other pathological states involving the metabolism of mucopolysaccharides and glycoproteins.
D000818:Animals; D001665:Binding Sites; D006528:Carcinoma, Hepatocellular / Q000378:metabolism; D004396:Coloring Agents; D006025:Glycosaminoglycans / Q000378:metabolism; D008113:Liver Neoplasms / Q000378:metabolism; D009369:Neoplasms / Q000175:diagnosis*; D009374:Neoplasms, Experimental / Q000378:metabolism; D011877:Radionuclide Imaging; D051381:Rats; D012428:Ruthenium / Q000378:metabolism
D004396:Coloring Agents; D006025:Glycosaminoglycans; D012428:Ruthenium