Pressure-flow relationships and pathological changes during renal preservation.
The renal pedicle of one kidney from each of four dogs was ligated for one hour. The contralateral kidney served as a control. Both kidneys were removed and perfused using the "Belzer" technique. Pressure-flow relationships were determined and biopsy samples taken. The vasculature was then injected with silicone rubber. Perfusion resistance, vascular filling with silicone rubber and observations made by electron microscopy were compared.
D000818:Animals; D004285:Dogs; D007511:Ischemia / Q000473:pathology; D007668:Kidney / Q000098:blood supply / Q000473:pathology* / Q000648:ultrastructure; D009926:Organ Preservation; D012039:Regional Blood Flow; D013997:Time Factors; D014021:Tissue Preservation