The binding of the mucoprotein from gastric mucus to cells in tissue culture and the inhibition of cell adhesion.
The mucoprotein, which is responsible for the formation of gastric mucous gel in pig, has been shown to bind equally well to suspensions of baby hamster kidney cells, polyoma-virus-transformed baby hamster kidney cells and HeLa cells. The binding of the mucoprotein to the cells is dependent on Ca 2
D000818:Animals; D001386:Azides / Q000494:pharmacology; D001665:Binding Sites / Q000187:drug effects; D002118:Calcium / Q000494:pharmacology; D002448:Cell Adhesion / Q000187:drug effects; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured; D002999:Clone Cells; D003208:Concanavalin A; D006224:Cricetinae; D005752:Gastric Mucins; D006367:HeLa Cells; D006801:Humans; D007457:Iodine Radioisotopes; D007668:Kidney; D008274:Magnesium / Q000494:pharmacology; D009088:Mucoproteins; D010434:Pepsin A / Q000378:metabolism; D011120:Polyomavirus; D011485:Protein Binding / Q000187:drug effects; D012710:Serum Albumin, Bovine; D013462:Sulfur Radioisotopes; D013552:Swine; D013696:Temperature
D001386:Azides; D005752:Gastric Mucins; D007457:Iodine Radioisotopes; D009088:Mucoproteins; D013462:Sulfur Radioisotopes; D003208:Concanavalin A; D012710:Serum Albumin, Bovine; D010434:Pepsin A; D008274:Magnesium; D002118:Calcium