Enzymes of fructose metabolism in human kidney.
Activities of enzymes involved in fructose metabolism were measured in samples of human kidney cortex and medulla. The enzymes are ketohexokinase, aldolase, NAD- and NADP-dependent alcohol dehydrogenase, aldehyde dehydrogenase, triokinase and glycerate kinase; hexose biphosphatase and sorbitol dehydrogenase were also investigated. With the exception of glycerate kinase, all enzymes involved in fructose metabolism were found in the human cortex and medulla. The enzyme levels in the medulla were low in comparison with the cortex.
D000429:Alcohol Oxidoreductases / Q000378:metabolism; D005632:Fructose / Q000378:metabolism*; D005634:Fructose-Bisphosphate Aldolase / Q000378:metabolism; D006593:Hexokinase / Q000378:metabolism; D006598:Hexosediphosphates; D006801:Humans; D007668:Kidney / Q000201:enzymology*; D007672:Kidney Cortex / Q000201:enzymology; D007679:Kidney Medulla / Q000201:enzymology; D009928:Organ Specificity; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D010770:Phosphotransferases / Q000378:metabolism
D006598:Hexosediphosphates; D005632:Fructose; D000429:Alcohol Oxidoreductases; D010770:Phosphotransferases; D006593:Hexokinase; D010744:Phosphoric Monoester Hydrolases; D005634:Fructose-Bisphosphate Aldolase