Whole-body autoradiography of 99Tcm-labelled pyrophosphate and related compounds in young rats.
The distribution of 99Tcm-labelled pyrophosphate in young rats was analysed by wholebody autoradiography and compared with those observed for 99Tcm-pertechnetate, 32P-labelled pyrophosphate and 85Sr-chloride. 99Tcm-labelled pyrophosphate was rapidly accumulated in bone and dentine and was similar to 32P-labelled pyrophosphate and 85Sr-chloride. The uptake of these substances in developing enamel was rather low in contrast to 99Tcm-pertechnetate, which had no affinity for bone.
D000818:Animals; D001345:Autoradiography; D001842:Bone and Bones / Q000378:metabolism; D002712:Chlorides / Q000378:metabolism; D003743:Dental Enamel / Q000378:metabolism; D003804:Dentin / Q000378:metabolism; D011756:Diphosphates / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D010761:Phosphorus Radioisotopes; D051381:Rats; D013131:Spine / Q000378:metabolism; D013154:Spleen / Q000378:metabolism; D013326:Strontium Radioisotopes; D013667:Technetium; D013950:Thymus Gland / Q000378:metabolism; D001743:Urinary Bladder / Q000378:metabolism
D002712:Chlorides; D011756:Diphosphates; D010761:Phosphorus Radioisotopes; D013326:Strontium Radioisotopes; D013667:Technetium