Murine oncornavirus activation in the pancreas during infection with Venezuelan equine encephalitis virus.
Electron microscopic studies of the pancreases of 3-week-old ICR Swiss mice infected with Venezuelan equine encephalitis virus and killed 6 days post inoculation (at which time they were moribund) indicated significantly more type-C particles than were found in uninfected controls. This phenomenon was apparently possible because of the microanatomy of the pancreas, in which interstital spaces allowed accumulation of virus particles.
D000818:Animals; D004683:Encephalomyelitis, Equine / Q000382:microbiology*; D004685:Encephalomyelitis, Venezuelan Equine / Q000382:microbiology*; D017988:Gammaretrovirus / Q000302:isolation & purification*; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure; D051379:Mice; D008813:Mice, Inbred ICR; D010179:Pancreas / Q000382:microbiology*; D012190:Retroviridae / Q000302:isolation & purification*; D014779:Virus Replication