Inhibition of growth of Coccidioides immitis on Sabouraud medium containing polymyxin B.
No growth of Coccidioides immitis occurred when fluid from infected tissue or arthrospores suspended in distilled water were plated on the surface of Sabouraud medium, solidified with refined agar, and containing 20 mg of polymyxin B per liter. Solidification of Sabouraud medium with unrefined agar completely abolished the anticoccidioidal activity of polymyxin B.
D000362:Agar / Q000494:pharmacology; D000818:Animals; D003045:Coccidioides / Q000187:drug effects / Q000254:growth & development*; D003047:Coccidioidomycosis / Q000382:microbiology; D004195:Disease Models, Animal; D008168:Lung / Q000382:microbiology; D011113:Polymyxins / Q000494:pharmacology*
D011113:Polymyxins; D000362:Agar