Some new observations in an intracranial germinoma.
A case of an intracranial germinoma from the suprasellar region of a 9-year-old girl was examined in the electron microscope. The tumor consists, for the most part, of both large polygonal and small lymphocyte-like elements. Annulate lamellae are common in the epithelial cells. The small blood vessels are fenestrated, and the endothelial cells contain tubular bodies, membrane-bounded vacuoles containing dense fluid and occasional tubules, arrays of tubules within the nuclear envelope and rough endoplasmic reticulum, and a markedly irregular luminal surface. Dense, lamellated structures are present in the widened, collagen-containing perivascular spaces.
D001932:Brain Neoplasms / Q000473:pathology*; D002196:Capillaries / Q000648:ultrastructure; D002462:Cell Membrane / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D002648:Child; D004407:Dysgerminoma / Q000473:pathology*; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D004727:Endothelium / Q000648:ultrastructure; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D005337:Fibrin / Q000032:analysis; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D008214:Lymphocytes / Q000648:ultrastructure; D014617:Vacuoles / Q000648:ultrastructure
D005337:Fibrin