Proviral sequences of baboon endogenous type C RNA virus in DNA of human leukaemic tissues.
Hybridisation of RNA from a baboon endogenous type C RNA virus to DNA from tissues of leukaemic patients indicates that a virus of this type is horizontally transmitted among humans. DNA from several patients with leukaemia hybridised 70% of the hybridisable RNA from baboon endogenous type C RNA virus (BaEV) and yielded hybrids of high tm, whereas DNA from normal human tissues hybridised only 23% of the BaEV RNA, and the tm of these hybrids was lower.
D000328:Adult; D000818:Animals; D001483:Base Sequence; D004273:DNA, Neoplasm / Q000032:analysis*; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000382:microbiology* / Q000635:transmission; D007962:Leukocytes / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D009693:Nucleic Acid Hybridization; D010215:Papio / Q000382:microbiology*; D012190:Retroviridae / Q000032:analysis* / Q000254:growth & development; D013154:Spleen / Q000382:microbiology
D004273:DNA, Neoplasm; D004279:DNA, Viral