[Investigation of cyclic renal adenosinmonophosphate (yamp)-excretion in pseudohypoparathyreoidism (author's transl)].
Report on a boy aged 6-1/2 years with pseudohypoparathyroidism. This is due to a genetic lack of PTH inducible adenocyclase. Even during vitamin D treatment renal camp formation by giving PTH extract cannot be stimulated, while in this situation. PTH shows a clearly phosphaturic effect. Whether this is due to a PTH potentiated vitamin D effect is discussed. The assay of camp in urine before and after stimulation with PTH extract has proved the most certain diagnostic criterion.
D000469:Alkaline Phosphatase / Q000097:blood; D002648:Child; D002762:Cholecalciferol / Q000627:therapeutic use; D000242:Cyclic AMP / Q000652:urine*; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology; D007677:Kidney Function Tests; D008297:Male; D010710:Phosphates / Q000097:blood; D011547:Pseudohypoparathyroidism / Q000175:diagnosis / Q000188:drug therapy / Q000652:urine*
D010710:Phosphates; D002762:Cholecalciferol; D000242:Cyclic AMP; D000469:Alkaline Phosphatase
Untersuchungen über das Verhalten der renalen cyclischen Adenosinmonophosphate-(CAMP)-Ausscheidung beim Pseudohypoparathyreoidismus