title: Effect of ACTH and bilateral gonadectomy on the adrenocortical tissue of an air-breathing fish -- Heteropneustes fossilis (Bloch).
abstract: The mammalian ACTH (20 I.U.) injected in Heteropneustes fossilis (Bloch) caused hyperplasia of the adrenocortical tissue. The interrenal as well as chrome cells became vacuolated. The interrenal nuclear size increased by 15% as an average than the control fishes. The glycogen granules were found to be absent from the interrenal cells. The effect of bilateral gonadectomy in both sexes has been marked in the gradual decrease of the interrenal nuclear diameter which 12 weeks after the operation, recorded nearly 25% reduction in size. The glycogen content was reduced considerably. Removal of gonads during maturation period bringing inhibition of hyperplasia of the gland at the time of spawning possibly indicates action of gonadal steroids on the physiological alterations of the interrenal cells.
mesh_terms: D000302:Adrenal Cortex / Q000166:cytology / Q000187:drug effects*; D000311:Adrenal Glands / Q000187:drug effects*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D002369:Castration; D002467:Cell Nucleus; D005399:Fishes / Q000502:physiology*; D006003:Glycogen / Q000378:metabolism; D006066:Gonads / Q000502:physiology; D006984:Hypertrophy / Q000209:etiology; D007668:Kidney / Q000378:metabolism
chemical_list: D000324:Adrenocorticotropic Hormone; D006003:Glycogen