[Cyclic 3',5'-adenosine monophosphate stimulation of chloramphenicol-acetyltransferase synthesis in bacterial cellular systems].
A study was made of the effect of cyclic cyclic 3',5'-adenosinmonophosphate (c-AMP) on the production of chloramphenicol-acetyltranspherase (CAT) enzyme by whole bacterial cells in the strains of E. coli CSH-2/R222 and WZ-78/R222 (cya855). It was shown that CAT synthesis in the E. coli WZ-78/R222 strain was two times less in comparison with the E. coli CSH-2/R222 strain. C-AMP only insignificantly increased the production of CAT by the E. coli CSH-2/R222 strain, but considerably influenced the production of this enzyme by the WZ-78/R222 strain.
D000123:Acetyltransferases / Q000096:biosynthesis*; D002701:Chloramphenicol / Q000096:biosynthesis*; D000242:Cyclic AMP / Q000494:pharmacology*; D004789:Enzyme Activation / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects* / Q000378:metabolism; D011815:R Factors; D013268:Stimulation, Chemical
D002701:Chloramphenicol; D000242:Cyclic AMP; D000123:Acetyltransferases
Stimuliatsiia tsiklichekim 3',5'-adenozinmonofosfatom sinteza khloramfenikol-atsetiltransferazy v bakterial'nykh kletochnykh sistemakh