DNA polymerase in pseudorabies virus infected cells.
The DNA polymerase activity in BHK 21/C13 cells infected with pseudorabies virus is inhibited by incubation with antiserum to pseudorabies but not by incubation with pre-immune serum or by antiserum to herpes simplex virus type 1 (HSV-1) or herpes simplex virus type 2 (HSV-2). It also differs from the cell enzyme and the enzymes in HSV-1 or HSV-2 infected cells in its requirement for KCl in the in vitro assay. It seems likely, therefore, that pseudorabies virus specifies its own DNA polymerase.
D002460:Cell Line; D002474:Cell-Free System; D004254:DNA Nucleotidyltransferases / Q000276:immunology / Q000378:metabolism*; D006564:Herpesviridae / Q000201:enzymology*; D011558:Herpesvirus 1, Suid / Q000201:enzymology* / Q000254:growth & development / Q000276:immunology; D007106:Immune Sera / Q000494:pharmacology; D011189:Potassium Chloride / Q000494:pharmacology; D018139:Simplexvirus / Q000201:enzymology / Q000276:immunology
D007106:Immune Sera; D011189:Potassium Chloride; D004254:DNA Nucleotidyltransferases