title: [Clinical experience of cefoxitin in the field of obstetrics and gynecology (author's transl)].
abstract: Cefoxitin was given to the 7 patients of infections in the field of obstetrics and gynecology, and the following results were obtained: 1) The clinical response was excellent in 2 patients, good in 4 and poor in 1 patient with the efficacy rate of 85.7%. Out of the 4 patients resistant to the previous therapy with other antibiotics, 3 patients responded to cefoxitin, and all the 3 patients of anaerobic infections responded satisfactorily to cefoxitin. 2) Microorganisms isolated were 2 strains each of E. coli and Staphylococcus aureus, 3 strains of Peptococcus and 1 strain of Eubacterium lentum. All the 8 strains isolated were sensitive to cefoxitin. As to bacteriological response, all the strains isolated were eradicated except 1 strain of Staphylococcus aureus which recurred on the 9th day after completion of the therapy with the eradication rate of 87.5%. 3) No subjective nor objective side effects were noted. Especially, the elevated GOT and GPT observed on a patient complicated with hepatitis prior to the initiation of cefoxitin treatment were found to be normal upon completion of the treatment.
mesh_terms: D000009:Abdominal Muscles; D000328:Adult; D000368:Aged; D002440:Cefoxitin / Q000627:therapeutic use*; D002585:Cesarean Section / Q000009:adverse effects; D005260:Female; D005402:Fistula / Q000188:drug therapy / Q000209:etiology; D005831:Genital Diseases, Female / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D010249:Parametritis / Q000188:drug therapy; D000292:Pelvic Inflammatory Disease / Q000188:drug therapy; D011183:Postoperative Complications; D011247:Pregnancy; D011702:Pyelitis / Q000188:drug therapy; D014946:Wound Infection / Q000188:drug therapy
chemical_list: D002440:Cefoxitin