Virological studies on gynaecological patients.
Endometrial epithelial cells and blood samples taken simultaneously with the curettage (first serum) of 138 patients suffering from menstrual bleeding disorders as well as materials obtained from 16 induced abortions, were studied for the presence of virus. Fourteen adenovirus 2 strains were isolated from samples of the patients. Endometrial epithelial cells of 35 patients were examined with immunofluorescence method and 23 of them displayed specific fluorescence referring to the presence of viral antigens, with adenovirus and herpesvirus antisera. Studying withserological reactions the first and second (convalescent) sera of patients, high titers were found against type 2 herpesvirus in both sera, and titer rise against the latent adenovirus types in the second sera. Neither infective virus nor the presence of viral antigens were demonstrable in materials obtained from induced abortions.
D000028:Abortion, Induced; D000256:Adenoviridae / Q000302:isolation & purification*; D000956:Antigens, Viral / Q000302:isolation & purification; D004717:Endometrium / Q000382:microbiology*; D004847:Epithelial Cells; D004848:Epithelium / Q000382:microbiology; D005260:Female; D006801:Humans; D008599:Menstruation Disturbances / Q000382:microbiology*; D011247:Pregnancy; D018139:Simplexvirus / Q000302:isolation & purification*
D000956:Antigens, Viral