Stimulation of microsomal drug-metabolizing enzymes in rat liver by 1,1,1,-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), pregnenolone-16 alpha-carbonitrile (PCN), and polychlorinated biphenyls (PCB's).
D000818:Animals; D001579:Benzopyrene Hydroxylase / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003579:Cytochrome Reductases / Q000378:metabolism; D003574:Cytochrome c Group; D003634:DDT / Q000494:pharmacology*; D004072:Digitonin / Q000494:pharmacology; D014453:Glucuronosyltransferase / Q000378:metabolism; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology*; D009575:Nitroanisole O-Demethylase / Q000378:metabolism; D010740:Phospholipases / Q000494:pharmacology; D011078:Polychlorinated Biphenyls / Q000494:pharmacology*; D011285:Pregnenolone Carbonitrile / Q000494:pharmacology*; D051381:Rats; D013268:Stimulation, Chemical; D014357:Trypsin / Q000494:pharmacology
D003574:Cytochrome c Group; D011285:Pregnenolone Carbonitrile; D003577:Cytochrome P-450 Enzyme System; D003634:DDT; D011078:Polychlorinated Biphenyls; D009575:Nitroanisole O-Demethylase; D001579:Benzopyrene Hydroxylase; D003579:Cytochrome Reductases; D014453:Glucuronosyltransferase; D010740:Phospholipases; D014357:Trypsin; D004072:Digitonin