[Translation of hormone receptor interactions into biological function. A hypothesis (author's transl)].
Published data revealing discrepancies between the kinetics of hormone binding and adenylate cyclase activation are critically analyzed. This analysis gave rise to the hypothesis concerning the translation of hormone receptor interactions into biological function, i.e.: adenylate cyclase activation. Because the lifetime of the hormone receptor complex is too long, other steps in signal transfer are considered for the control of adenylate cyclase activity.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D001665:Binding Sites; D002462:Cell Membrane / Q000378:metabolism / Q000648:ultrastructure; D010856:Columbidae; D004789:Enzyme Activation; D006150:Guanine Nucleotides / Q000378:metabolism; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D051379:Mice; D008956:Models, Chemical; D011485:Protein Binding; D051381:Rats; D011956:Receptors, Cell Surface
D006150:Guanine Nucleotides; D006728:Hormones; D011956:Receptors, Cell Surface; D000262:Adenylyl Cyclases
Die Ubersetzung der Hormonrezeptorwechselwirkung in biologische Funktion. Eine Hypothese