Demonstation that thymine dimers are excised as oligonucleotides from specifically incised ultraviolet-irradiated deoxyribonucleic acid.
The average size of the dimer-containing acid-soluble oligonucleotides after incubation of specifically incised DNA with two dimer excising nuclease activities has been determined to be about 8 nucleotides.
D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D002417:Cattle; D003090:Coliphages / Q000201:enzymology / Q000378:metabolism; D004254:DNA Nucleotidyltransferases / Q000378:metabolism*; D004269:DNA, Bacterial / Q000378:metabolism* / Q000528:radiation effects; D004279:DNA, Viral / Q000378:metabolism / Q000528:radiation effects; D004720:Endonucleases / Q000378:metabolism; D004926:Escherichia coli / Q000201:enzymology / Q000378:metabolism*; D009691:Nucleic Acid Denaturation; D009841:Oligonucleotides / Q000378:metabolism*; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D011830:Radiation Effects; D012910:Snake Venoms; D013154:Spleen / Q000201:enzymology; D013941:Thymine / Q000378:metabolism; D014466:Ultraviolet Rays
D004269:DNA, Bacterial; D004279:DNA, Viral; D009841:Oligonucleotides; D012910:Snake Venoms; D004254:DNA Nucleotidyltransferases; D004720:Endonucleases; D000469:Alkaline Phosphatase; D010727:Phosphoric Diester Hydrolases; D013941:Thymine