Adenovirus type 12 infection of defined mouse-human hybrid cell clones.
Human adenovirus type 12 does not multiply in mouse cells; only viral T-antigen is detected. Mouse-human cell hybrid clones containing human chromosomes A3, B5, C7, C11, C12, D14, E17, F19 and F20, support synthesis of adenovirus DNA and capsid antigens.
D000256:Adenoviridae / Q000378:metabolism*; D000257:Adenoviridae Infections; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002999:Clone Cells / Q000378:metabolism; D004279:DNA, Viral / Q000096:biosynthesis*; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D006822:Hybrid Cells / Q000378:metabolism*; D051379:Mice; D010710:Phosphates / Q000378:metabolism; D013936:Thymidine / Q000378:metabolism
D000956:Antigens, Viral; D004279:DNA, Viral; D010710:Phosphates; D013936:Thymidine