[Dynamics of plasma corticoid levels following intranuscular or intravenous ACTH-stimulation in children and adults (author's transl)].
Following ACTH-stimulation, in 40 patients plasma corticoid levels (CPB-technique) were determined every 15 min for three hours to demonstrate the period of maximal increase. There was no significant difference in the increase of plasma cortisol following intravenous or intramuscular injection of ACTH (beta1-23). Peak values were reached at 60 min (65.2 +/- 3.2 mug/100 ml). This is considered to be the right moment for blood sampling when using a short ACTH-test.
D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D011863:Radioimmunoassay; D013997:Time Factors
D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
Die dynamik der Corticoid-Plasmaspiegel nach ACTH bei Kindern und Erwachsenen unter i.v.- und i.m.-Applikation