Partial amino-acid sequence of NAD-specific glutamate dehydrogenase of Neurospora crassa.
Parts of the primary structure of the NAD-specific glutamate dehydrogenase [L-glutamate:NAD oxidoreductase (deaminating), EC 1.4.1.2] from Neurospora crassa are presented. Segments of the sequence representing 886 unique amino-acid residues have been determined; the largest contains 267 residues. There are only short regions of possible homology between this enzyme and the glutamate dehydrogenases of bovine liver or the NADP-specific enzyme of Neurospora. The large size of the subunit (116,000 molecular weight) of the NAD-specific glutamate dehydrogenase is unusual when compared to other known dehydrogenases.
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000626:Aminopeptidases; D002268:Carboxypeptidases; D003488:Cyanogen Bromide; D005969:Glutamate Dehydrogenase / Q000032:analysis*; D009243:NAD; D009491:Neurospora / Q000201:enzymology*; D009492:Neurospora crassa / Q000201:enzymology*; D010447:Peptide Hydrolases; D014357:Trypsin
D000596:Amino Acids; D009243:NAD; D005969:Glutamate Dehydrogenase; D002268:Carboxypeptidases; D010447:Peptide Hydrolases; D000626:Aminopeptidases; D014357:Trypsin; D003488:Cyanogen Bromide