title: Antibody formation to dog pulp tissue altered by AH-26 sealer via the root canal.
abstract: Pulp tissue from three experimental dogs was tested for its antigenicity before and after incubation with AH-26 sealer. identical to Reactions to Arthus skin tests showed an increased response to pulp that had been incubated in AH-26, washed, and then injected, as compared with the material alone. Hemagglutinating antibody titers (1/500 to 1/800) were obtained from pulp tissue altered by AH-26. Inhibition tests showed the apecificity of the antibody to be at a dilution titer of 1:400. Therefore, a mixture of AH-26 sealer altered dog pulp tissue and rendered it antigenically active, and a specific humoral response was produced.
mesh_terms: D000372:Agglutination Tests; D000818:Animals; D000906:Antibodies / Q000032:analysis; D000917:Antibody Formation; D000941:Antigens; D001183:Arthus Reaction / Q000276:immunology; D003782:Dental Pulp / Q000276:immunology*; D003786:Dental Pulp Cavity / Q000276:immunology*; D003790:Dental Pulp Necrosis / Q000276:immunology; D004285:Dogs; D007114:Immunization; D008297:Male; D012387:Root Canal Filling Materials; D012882:Skin Tests
chemical_list: D000906:Antibodies; D000941:Antigens; D012387:Root Canal Filling Materials