Immunization against feline oncarnavirus disease using a killed tumor cell vaccine.
Specific pathogen-free cats were immunized with an inactivated feline oncornavirus tumor cell vaccine. Immunized cats produced high antibody titers to the feline oncornavirus-associated cell membrane antigen and were protected from oncogenic feline sarcoma virus challenge. However, immunization did not produce virus-neutralizing antibody nor did it prevent viremia.
D000818:Animals; D000912:Antibodies, Neoplasm / Q000032:analysis; D000918:Antibody Specificity; D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D002415:Cats; D003080:Cold Temperature; D009858:Oncogenic Viruses / Q000276:immunology; D005253:Sarcoma Viruses, Feline / Q000276:immunology; D012513:Sarcoma, Experimental / Q000276:immunology / Q000517:prevention & control*; D014412:Tumor Virus Infections / Q000517:prevention & control*; D014611:Vaccination
D000912:Antibodies, Neoplasm; D000951:Antigens, Neoplasm; D000956:Antigens, Viral