Efficacy of albendazole for treatment of naturally acquired nematode infections in Washington cattle.
Albendazole, methyl 5-propylthio-1H-benzimidazol-2-yl carbamate, was given as a bolus (7.68 to 8.18 mg/kg of body weight) to cattle naturally infected with gastrointestinal nematodes and lungworms in a controlled trial. Over 99% of adult Ostertagia ostertagi, Trichostrongylus longispicularis, Cooperia oncophora, Nematodirus helvetianus, and Dictyocaulus viviparus were removed by the treatment. Efficacy against immature O ostertagi, early fourth-stage O ostertagi, and Oesophagostomum radiatum was 95.2%, 86.6%, and 96.7%, respectively. In a field trial, the same compound administered in a paste formulation (at approximately 7.5 mg/kg) eliminated over 99% of strongylin and Moniezia eggs from feces of treated cattle.
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D004022:Dictyocaulus Infections / Q000188:drug therapy; D008989:Monieziasis / Q000188:drug therapy; D009349:Nematode Infections / Q000662:veterinary*; D014252:Trichostrongyloidiasis / Q000188:drug therapy / Q000662:veterinary; D014861:Washington
D000871:Anthelmintics; D001562:Benzimidazoles