title: [Investigations on immunity against poliomyelitis (author's transl)].
abstract: Six virus laboratories from various parts of the German Federal Republic and West Berlin undertook investigations into polio-myelitis immunity in 1972. A total of 267 persons aged up to 20 years were investigated for neutralizing antibodies against the three types of polio virus. The study showed that from the fourth year of life approximately 70% of the persons investigated had antibodies against all three types of polio virus. In some younger children the equivalent values were considerably lower. After the fourth year of life there were only slight differences in the humoral immunity against the three polio virus types. There was no evidence that the immunity level had deteriorated up to the 20th year of life and thus there is no indication of the necessity for a repeat immunisation at a certain time. The investigation confirmed that three oral administrations of trivalent vaccine, as are now generally recommended as basic immunization in the German Federal Republic, result in a conversion rate of over 90% against each of the three virus types.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000914:Antibodies, Viral / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D005860:Germany, West; D006801:Humans; D007110:Immunity, Active; D007223:Infant; D011051:Poliomyelitis / Q000276:immunology*; D017955:Poliovirus / Q000145:classification; D011055:Poliovirus Vaccine, Oral; D014611:Vaccination
chemical_list: D000914:Antibodies, Viral; D011055:Poliovirus Vaccine, Oral
vernacular_title: Untersuchungen über die Immunitätslage gegen Poliomyelitis. Ergebnisse einer kooperativen Studie der Deutschen Vereinigung zur Bekämpfung der Kinderlähmung und anderer Viruskrankheiten