title: Homology and relationship between the genomes of papovaviruses, BK virus and simian virus 40.
abstract: A number of hybridization techniques have been used to assess the homology between the genomes of BK virus (BKV) and simian virus 40 (SV40). A noncontiguous set of homologous sequences has been localized primarily within the late region of the SV40 genome, and these sequences presumably account for the cross-reaction between V-antigens of the two viruses. The reason for the relatively strong crossreaction between SV40 and BKV T-antigens is still unclear. The sequence homology and similarity in genomic organization suggest a close relationship between these papovaviruses.
mesh_terms: D001739:BK Virus / Q000032:analysis*; D001483:Base Sequence; D004262:DNA Restriction Enzymes; D004279:DNA, Viral; D003854:Deoxyribonucleotides / Q000032:analysis; D005796:Genes; D006193:Haemophilus influenzae / Q000201:enzymology; D008854:Microscopy, Electron; D009693:Nucleic Acid Hybridization; D027383:Papillomaviridae / Q000032:analysis*; D027382:Polyomaviridae; D011120:Polyomavirus / Q000032:analysis*; D013539:Simian virus 40 / Q000032:analysis*; D013045:Species Specificity
chemical_list: D004279:DNA, Viral; D003854:Deoxyribonucleotides; D004262:DNA Restriction Enzymes