[Inhibition of ethanol exidation on prolonged fasting in man: reversibility on fructose infusion(author's transl)].
Fasting for over 36 hours was found to inhibit ethanol metabolism in healthy volunteers by 43% (P less than 0.01) compared with values obtained after 12 hours' fasting. Ethanol oxidation was not inhibited by prolonged fasting when it was stimulated by intravenous fructose. The explanation for this effect is thought to lie in the inhibition of alcohol oxidation mainly by limiting the rate of NADH-reoxidation in the liver.
D000429:Alcohol Oxidoreductases; D000431:Ethanol / Q000097:blood / Q000378:metabolism*; D005215:Fasting; D005632:Fructose / Q000008:administration & dosage*; D006801:Humans; D008099:Liver / Q000187:drug effects; D009243:NAD; D010084:Oxidation-Reduction; D013997:Time Factors
D009243:NAD; D005632:Fructose; D000431:Ethanol; D000429:Alcohol Oxidoreductases
Hemmung des Athanolabbaus beim Menschen durch Fasten: Reversibilität durch Fructose-Infusion