title: [2 cases of hemolytic complications during intermittent treatment with rifampicin].
abstract: Two cases are presented, of hemolytic jaundice, determined by rifampicin. The first occured in a woman in whom treatment was started again after an interruption of 6 months and the second in a man undergoing intermittent treatment that had been tolerated very well for 3 months. Following the extension of the application of rifampicin in intermittent treatment might occur more frequently. Posology apparently has a major role and some precautions are to be taken.
mesh_terms: D000328:Adult; D000743:Anemia, Hemolytic / Q000139:chemically induced*; D000906:Antibodies / Q000032:analysis; D003298:Coombs Test; D004342:Drug Hypersensitivity / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D012293:Rifampin / Q000009:adverse effects* / Q000627:therapeutic use; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
chemical_list: D000906:Antibodies; D012293:Rifampin
vernacular_title: Două observatii de accidente hemolitice în cursul tratamentului intermitent cu rifampicină