Malignant fibrous histiocytoma associated with bone infarcts: report of a case.
A caisson worker with symmetrical bone infarcts in the tibiae demonstrated a malignant transformation of one of the bone infarcts with wide-spread metastases to the lungs and viscera. Histologically, the tumor was found to be a malignant fibrous histiocytoma and despite amputation, the patient died approximately one year following the diagnosis. This case lends credence to the concept of a cause and effect relationship existing between bone infarcts and the subsequent development of bone sarcoma.
D000328:Adult; D001859:Bone Neoplasms / Q000209:etiology / Q000473:pathology*; D001842:Bone and Bones / Q000098:blood supply; D018219:Histiocytoma, Benign Fibrous / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007238:Infarction / Q000150:complications*; D008297:Male; D013977:Tibia