Localised myeloma with osteogenesis and Russell body formation.
A case of an osteosclerotic myeloma of the mandible is described. Bone formation took the form of prominent sunray spiculation and radiologically mimicked an osteosarcoma. No other well-documented solitary lesion of this type could be found in the English literature. In addition, this tumour contained an abundance of intracytoplasmic Russell bodies and also produced a paraprotein. The paraprotein peak disappeared after resection.
D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008297:Male; D008334:Mandible / Q000473:pathology*; D008339:Mandibular Neoplasms / Q000473:pathology*; D008854:Microscopy, Electron; D008875:Middle Aged; D010012:Osteogenesis; D010950:Plasma Cells / Q000648:ultrastructure; D010954:Plasmacytoma / Q000473:pathology*