[Antibodies against the Epstein-Barr virus, capsid antigen in children with malignant neoplasms (author's transl)].
Sera from children were tested for antibodies to viral capsid antigens of Epstein-Barr virus. The method applied was the indirect immunofluorescence test. 25 sera from healthy donors were titrated as controls. In 14 patients with acute lymphocytic leukemia we found low levels, a tiny little girl with chronic myelocytic leukemia (?) AND THREE CHILDREN.WITH LYMPHOPROLIFERATIVE DISORDERS SHOWed highly increased serological reactivities. Investigated children with other kinds of tumours did not serologically differ significantly from the control group. Further investigations should clarify the role of this infectious agent.
D000367:Age Factors; D000914:Antibodies, Viral / Q000032:analysis*; D002213:Capsid / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005455:Fluorescent Antibody Technique; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D007223:Infant; D007945:Leukemia, Lymphoid / Q000175:diagnosis / Q000276:immunology; D007951:Leukemia, Myeloid / Q000276:immunology; D008223:Lymphoma / Q000175:diagnosis / Q000276:immunology; D008297:Male; D008527:Medulloblastoma / Q000276:immunology; D009369:Neoplasms / Q000175:diagnosis / Q000276:immunology*; D012208:Rhabdomyosarcoma / Q000276:immunology; D013724:Teratoma / Q000276:immunology; D013736:Testicular Neoplasms / Q000276:immunology
D000914:Antibodies, Viral
Epstein-Barr Viruscapsidantikörper bei kindlichen Malignomen