Participation of manganese ions complexed with tRNA in the interaction with amino acids and dipeptides.
Carboxyl groups of glycine, beta-alanine, gamma-aminobutyric acid and diglycine interact with Mn2+ coordinated by tRNA, as revealed by 1H and 13C NMR studies. The amino groups of these compounds interact with tRNA phosphate groups. The distances between the coordinated Mn2+ and carboxyl groups and the alpha-protons of glycine were determined. The role of Mn2+ and Mg2+ complexed with nucleic acids in the formation of specific complexes between proteins and nucleic acids is discussed.
D000409:Alanine / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism*; D000613:Aminobutyrates / Q000378:metabolism; D001665:Binding Sites; D004151:Dipeptides / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy; D005998:Glycine / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008345:Manganese / Q000378:metabolism*; D008433:Mathematics; D012343:RNA, Transfer / Q000378:metabolism*; D013329:Structure-Activity Relationship
D000596:Amino Acids; D000613:Aminobutyrates; D004151:Dipeptides; D008345:Manganese; D012343:RNA, Transfer; D000409:Alanine; D005998:Glycine