title: [Dynamics of changes in the activity of plasma lactate dehydrogenase, leucylarylamidase and GOT and GPT aminotransferases in poultry following damage to the organism caused by cadmium and tetrachloromethane].
abstract: In the experiments performed with broilers, after a per os application of tetrachloromethane and cadmium (Cd+2), the activity of lactate dehydrogenase (LDH), leucylarylamidase (LA), and the GOT and GPT amino transferase was determined in the blood plasm. By means of an electrophoretic division of the blood plasm of clinically healthy broilers one enzymatically active fraction of LA and LDH was ascertained. The injury caused to the organism of poultry by carbon tetrachloride and cadmium did not affect the heterogeneity of these two enzymes. After an application of tetrachloromethane (CCl4) in the dose of 8 and 10 ml kg-1 the total activity of LDH and LA changed. The influence of cadmium on the organism in the total dose of 200 mg kg-1 resulted in the changed activity of LDH, GOT, and LA. From the results obtained it has been assumed that the examined activity of LDH, GOT, and LA can be utilized for the diagnosing of non-specific injuries of the organism of poultry.
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D002105:Cadmium Poisoning / Q000201:enzymology / Q000662:veterinary*; D002252:Carbon Tetrachloride Poisoning / Q000201:enzymology / Q000662:veterinary*; D002645:Chickens; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D007931:Leucyl Aminopeptidase / Q000097:blood*; D011041:Poisoning / Q000201:enzymology / Q000662:veterinary; D011201:Poultry Diseases / Q000201:enzymology*; D000637:Transaminases / Q000097:blood*
chemical_list: D007770:L-Lactate Dehydrogenase; D000637:Transaminases; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D007931:Leucyl Aminopeptidase
vernacular_title: Dynamika zmien aktivity laktátdehydrogenázy, leucylarylamidázy a aminotransferázy got a gpt v krvnej plazme hydiny po poskodení organizmu kadmion a tetrachlôrmetánom