title: Recurrence of Down's syndrome associated with microchromosome.
abstract: We report a family with five members presenting an extra bisatellited microchromosome. Two of them also present trisomy 21. We discuss the relationship between trisomy and the extra chromosome.
mesh_terms: D000328:Adult; D002869:Chromosome Aberrations; D004314:Down Syndrome / Q000235:genetics*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010375:Pedigree; D014314:Trisomy