[Mechanism of the appearance of nuclear inclusions with microfilaments and microtubules in sympathetic neurons. Influence of dibutyryl-adenosine 3'-5' monophosphate and theophylline].
As we have shown previously the nucleus of sympathetic neurons contains microtubules and microfilaments giving rise to highly organized inclusions. Present in vivo experiments on cat stellate ganglia have shown that dibutyryl cyclic AMP and theophyllin induce an increase of their frequency (up to 8.5 fold). These and earlier observations lead us to conclude that cyclic AMP mediates the process of nuclear microtubules and microfilaments assembly from preformed protein subunits.
D000818:Animals; D003994:Bucladesine / Q000494:pharmacology*; D002415:Cats; D002467:Cell Nucleus / Q000187:drug effects* / Q000502:physiology / Q000648:ultrastructure; D066298:In Vitro Techniques; D008297:Male; D008870:Microtubules / Q000187:drug effects* / Q000502:physiology; D013564:Sympathetic Nervous System / Q000648:ultrastructure*; D013806:Theophylline / Q000494:pharmacology*
D003994:Bucladesine; D013806:Theophylline
Recherches sur le mécanisme d'apparition des inclusions nucleaires à microfilaments et à microtubules des neurones sympathiques. Influence du dibutyryl-adénosine 3'-5' monophosphate cyclique et de la théophylline