title: The conformational states of oxidized and oxygenated beef-heart cytochrome c oxidase.
abstract: 1. The "oxygenated" form of cytochrome has been generated by treatment of the enzyme with ascorbic acid. 2. "Oxygenated oxidase" so generated is stable over long periods (24 h). 3. Sedimentation velocity experiments have shown the "oxygenated" oxidase to be a less compact molecule than the oxidized.
mesh_terms: D000818:Animals; D001205:Ascorbic Acid; D001665:Binding Sites; D002417:Cattle; D004355:Drug Stability; D003576:Electron Transport Complex IV; D008970:Molecular Weight; D009206:Myocardium / Q000201:enzymology*; D010084:Oxidation-Reduction; D011485:Protein Binding; D011487:Protein Conformation; D013053:Spectrophotometry; D013997:Time Factors; D014461:Ultracentrifugation; D014783:Viscosity
chemical_list: D003576:Electron Transport Complex IV; D001205:Ascorbic Acid