Glycerol phosphate shuttle in virus-transformed cells in culture.
The glycerol phosphate shuttle is shown not only to be present and functional in virus-transformed cells, but its level is higher than in normal cells in culture. The increased aerobic glycolysis that has been demonstrated for these cells after transformation, therefore, is not due to an impairment of hydrogen transfer pathways.
D001358:Avian Sarcoma Viruses; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured; D005947:Glucose / Q000378:metabolism; D005993:Glycerolphosphate Dehydrogenase / Q000378:metabolism; D005994:Glycerophosphates / Q000378:metabolism*; D006019:Glycolysis; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D009243:NAD / Q000378:metabolism
D005994:Glycerophosphates; D009243:NAD; D005993:Glycerolphosphate Dehydrogenase; D007770:L-Lactate Dehydrogenase; D005947:Glucose