Relationship between Epstein-Barr virus-associated nuclear antigen and cell viability in human cell lines.
The relationship between the cell viability and frequency of cell with Epstein-Barr virus (EBV)-associated nuclear antigen was investigated in cultures of 4 EBV-carrier lymphoblastoid cell lines, by means of anti-complement immunofluorescence. The percentages of viable cells and those of EB nuclear antigen-positive cells were close to each other in the entire course of cultivation of all cell lines. This leads to a conclusion that absence of EB nuclear antigen in a given cell population should be evaluated in relation to cell viability.
D000956:Antigens, Viral / Q000032:analysis*; D002460:Cell Line; D002467:Cell Nucleus / Q000276:immunology; D002470:Cell Survival; D003165:Complement System Proteins; D005455:Fluorescent Antibody Technique; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D008214:Lymphocytes; D008722:Methods
D000956:Antigens, Viral; D003165:Complement System Proteins