Vertical transmission of type I and type 2 Herpes simplex virus infection in hamsters.
The relation of type 2 herpes simplex virus infection during the several stages of embryogenesis of hamster was examined using histopathological and immunofluorescent techniques. The comparative investigation between type 2 and type 1 was done. Both types of herpes simplex virus caused placental lesions and vertical transmission in fetuses when the virus was inoculated intravenously into pregnant hamsters at the middle and late stage of gestation.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D006224:Cricetinae; D005260:Female; D005313:Fetal Death / Q000382:microbiology; D005327:Fetal Resorption / Q000382:microbiology; D005455:Fluorescent Antibody Technique; D006561:Herpes Simplex / Q000151:congenital* / Q000276:immunology / Q000473:pathology; D008431:Maternal-Fetal Exchange; D009215:Myometrium / Q000473:pathology; D010920:Placenta / Q000473:pathology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D012703:Serotyping; D018139:Simplexvirus / Q000472:pathogenicity*
D000914:Antibodies, Viral; D000956:Antigens, Viral