Effect of immunization with attenuated Mycobacterium bovis (BCG) on experimental herpetic keratitis.
Mycobacterium bovis (BCG, Pasteur strain) was injected intraperitoneally into guinea pigs and rabbits on the 19th and 5th days prior to the intracorneal inoculation of Herpesvirus hominis. During a three-day and nine-day observation period, respectively, the BCG had no significant effect on the clinical course of the herpetic keratitis and no effect on the titer of virus present in the infected corneas.
D000818:Animals; D001500:BCG Vaccine; D003588:Cytopathogenic Effect, Viral; D004195:Disease Models, Animal; D006168:Guinea Pigs; D007167:Immunotherapy; D007274:Injections, Intraperitoneal; D007635:Keratitis, Dendritic / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D007668:Kidney; D008297:Male; D011817:Rabbits; D018139:Simplexvirus / Q000032:analysis; D014613:Vaccines, Attenuated
D001500:BCG Vaccine; D014613:Vaccines, Attenuated