Spontaneous lymphoma associated with Herpesvirus saimiri in owl monkeys.
Two cases of lymphoma and one case of lymphoproliferative disease were found in a group of 7 owl monkeys imported into our colony as a single group. Herpesvirus saimiri (HVS) was isolated from the tumor cells of 1 lymphoma by cocultivation and from kidney cell cultures from the monkey with lymphoproliferative disease. Antibody to HVS was found in serum samples from 2 monkeys positive for HVS but not in the sera from the 4 clinically normal monkeys. Antibody to Epstein-Barr virus-infected cells was also found in the serum from the animal with lymphoma.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D003588:Cytopathogenic Effect, Viral; D006168:Guinea Pigs; D006564:Herpesviridae; D004854:Herpesvirus 4, Human / Q000276:immunology; D007938:Leukemia / Q000635:transmission / Q000662:veterinary; D008223:Lymphoma / Q000276:immunology / Q000635:transmission / Q000662:veterinary*; D008992:Monkey Diseases / Q000635:transmission*; D010568:Peru
D000956:Antigens, Viral