Treatment of heterozygous type II hyperlipidemia by partial ileal bypass in a pediatric population.
Nine patients underwent partial ileal bypass as management for heterozygous type II hyperlipidemia.  The average age of this group was 12.5 yr. Follow-up has ranged from 1 to 6 yr. The growth and development of these children proceeded normally. The overall average serum cholesterol reduction was 33% when compared to the preoperative but postdietary control value. Side effects of the procedure include transient diarrhea and inability to absorb vitamin B12, requiring periodic parenteral administration. Partial ileal bypass has been shown to be an effective and obligatory method of treatment of hypercholesterolemia in children.
D000293:Adolescent; D000367:Age Factors; D001161:Arteriosclerosis / Q000209:etiology; D002648:Child; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications / Q000601:surgery*; D006949:Hyperlipidemias / Q000150:complications / Q000235:genetics* / Q000601:surgery*; D007082:Ileum / Q000601:surgery*; D008077:Lipoproteins, LDL / Q000097:blood*; D008297:Male
D008077:Lipoproteins, LDL; D002784:Cholesterol