Cation-induced immunosuppression: the effect of lithium or Arthus reactivity, delayed hypersensitivity and antibody production in the rat.
Arthus reactivity and delayed skin sensitivity to bovine serum albumin (BSA), and anti-BSA antibody production were markedly impaired in female Wistar rats repeatedly injected with lithium chloride.
D000818:Animals; D000917:Antibody Formation; D001183:Arthus Reaction / Q000276:immunology*; D001835:Body Weight; D005260:Female; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D007074:Immunoglobulin G / Q000096:biosynthesis; D007075:Immunoglobulin M / Q000096:biosynthesis; D007165:Immunosuppression Therapy; D007249:Inflammation / Q000276:immunology; D008094:Lithium / Q000494:pharmacology*; D009929:Organ Size; D051381:Rats; D013154:Spleen / Q000033:anatomy & histology; D013950:Thymus Gland / Q000033:anatomy & histology
D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008094:Lithium