Relationship between serum cholinesterase and low density lipoproteins in children with nephrotic syndrome.
1. A significant increase in the activity of serum cholinesterase and concentration of dextran sulphate precipitable lipoproteins, cholesterol and triglycerides was observed in sixteen children with a diagnosis of nephrotic syndrome when compared with the values obtained in 22 other normal children of comparable ages. 2. In 7 children with nephrotic syndrome serum concentrations of beta-lipoprotein and cholinesterase were markedly higher in the acute stage compared to the convalescent stage. A working hypothesis is proposed to explain the hyperlipoproteinemia in nephrotic syndrome.
D002648:Child; D002802:Cholinesterases / Q000097:blood*; D003911:Dextrans; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood*; D008832:Microchemistry; D009404:Nephrotic Syndrome / Q000097:blood* / Q000201:enzymology; D014280:Triglycerides / Q000097:blood
D003911:Dextrans; D008077:Lipoproteins, LDL; D014280:Triglycerides; D002802:Cholinesterases