[Myotonic seizures; the action of curare or related compounds on myotonia (author's transl)].
Myotonic seizures with apnea are alarming but temporary incidents occurring during curaization of a myotonic patient. Experience with regional curaization in myotonia shows that it is induced only by suxamethonium and it is only an exaggeration of the fasciculations produced by this compound. In contrast, however, competitive curare compounds have no effect on myotonia. The myotonic seizure, which is specific to myotonia, is radically different from the other respiratory accidents common to muscular dystrophies.
D000293:Adolescent; D003472:Curare / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009222:Myotonia / Q000188:drug therapy*; D003473:Neuromuscular Nondepolarizing Agents / Q000627:therapeutic use*; D012640:Seizures / Q000188:drug therapy*; D013390:Succinylcholine / Q000494:pharmacology; D014403:Tubocurarine / Q000494:pharmacology
D003473:Neuromuscular Nondepolarizing Agents; D003472:Curare; D013390:Succinylcholine; D014403:Tubocurarine
Les crises myotoniques; l'action des curares sur la myotonie.