Concentric nuclear inclusions.
Membrane bound concentric lamellar inclusions were found in the nuclei of pancreatic acinar cells of a patient with multiple primary neoplasms and in the parotid acinar cells of a patient with systemic lupus erythematosus. It is proposed that these inclusions form from rough cisternae sequestered in the nucleus.
D007516:Adenoma, Islet Cell / Q000473:pathology; D000328:Adult; D002467:Cell Nucleus / Q000648:ultrastructure*; D002648:Child; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008180:Lupus Erythematosus, Systemic / Q000473:pathology; D008566:Membranes; D008854:Microscopy, Electron; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D010179:Pancreas / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000473:pathology; D010306:Parotid Gland / Q000473:pathology