title: [Determination of the iodine content of the thyroid by means of fluorescence scans (author's transl)].
abstract: A procedure is described in which stable 127I in the thyroid is induced to fluorescence (28.5 keV) by 241Am (59.5 keV). The radiation is registered on a Si (Li) detector and can be used in order to obtain a scintigram or to determine the concentration of127I in the thyroid at any selected point. The apparatus is available commercially and has been adapted for use with a scanner. Measurements using collimation of 3.5 to 4 cm revealed a focus with a marked tomographic effect. The sensitivity of the apparatus was investigated by using solutions of varying iodine concentrations; calibration curves for determining iodine concentration in thyroid tissue were obtained. It is necessary to take account of the thickness of the thyroid gland and of the superficial tissues because of the marked attenuation of the radiation within the tissues. Radiation dose to the thyroid during the scintigram was about 0.1 mGy (10 mrd), i.e. about 5% of a conventional TC scintigram. There is no whole body irradiation.
mesh_terms: D006801:Humans; D007455:Iodine / Q000032:analysis*; D007457:Iodine Radioisotopes; D008722:Methods; D011877:Radionuclide Imaging; D013961:Thyroid Gland / Q000032:analysis* / Q000000981:diagnostic imaging
chemical_list: D007457:Iodine Radioisotopes; D007455:Iodine
vernacular_title: Untersuchung des Jodgehalts der Schilddrüse durch Fluoreszenzanregung.