title: [Results of application of CS-1170 to pediatric infections (author's transl)].
abstract: CS-1170 was administered in a total of 11 cases including respiratory infections, urinary-tract infections, and subacute bacterial endocarditis. It was effective in all of the cases; markedly effective in a case of bronchopneumonia with underlying Down's syndrome and infantile spasm and in 2 cases of urinary-tract infections with E. coli. The fact that it was effective for urinary-tract infection with E. coli which showed no sensitivity to ampicillin or cefazolin demonstrates the clinical significance and usefulness of CS-1170 which is said to have a strong antibacterial activity for bacterial producing beta-lactamase. No side effect was observed.
mesh_terms: D000367:Age Factors; D001424:Bacterial Infections / Q000188:drug therapy*; D002511:Cephalosporins / Q000627:therapeutic use*; D002513:Cephamycins / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications; D004341:Drug Evaluation; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications; D006801:Humans; D007223:Infant; D008297:Male
chemical_list: D002511:Cephalosporins; D002513:Cephamycins