Iris tissue reaction to dacron and silk in primates: evaluation for intraocular lens fixation.
Dacron, silk, and a combination of the two were evaluated for tissue ingrowth response in the primate iris with a view towards the feasibility of using these materials for intraocular lens fixation. The materials were well tolerated by all eyes, with no inflammation after seven days and no cases of endophthalmitis occurring. Adherence to iris was strong in silk-containing materials at 14 days by gross and histologic examination, and the Dacron-silk combination was judged most suitable for potential human use.
D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects*; D005549:Foreign-Body Reaction / Q000209:etiology*; D000882:Haplorhini; D007498:Iris / Q000473:pathology / Q000601:surgery; D007910:Lenses, Intraocular / Q000379:methods*; D008252:Macaca fascicularis; D011093:Polyethylene Terephthalates / Q000009:adverse effects*; D013537:Sutures / Q000592:standards
D001672:Biocompatible Materials; D011093:Polyethylene Terephthalates