C-Type virus particles in a cell line from a lymphosarcoma of a nude mouse.
C-type virus particles were observed by electron microscopy in cultures of a cell line (NML-1) derived from a lymphosarcoma that arose spontaneously in a nude NIH outbred mouse. The presence of such particles indicated that human tumors heterotransplanted in nude mice might become contaminated with murine oncornaviruses.
D000818:Animals; D002460:Cell Line; D008228:Lymphoma, Non-Hodgkin / Q000382:microbiology* / Q000473:pathology; D051379:Mice; D008819:Mice, Nude; D008854:Microscopy, Electron; D012190:Retroviridae / Q000302:isolation & purification*