Structural investigation of the antibiotic ristomycin A. Synthesis of ristobiose and ristotriose.
Proof is given by synthesis confirming the structure of ristobiose as 2-O-alpha-D-mannopyranosyl-D-glucose (IV) and ristotriose as O-alpha-L-rhamnopyranosyl (1 leads to 6)-O-[alpha-D-mannopyranosyl (1 leads to 2)]-D-glucose (X) which are obtained from ristomycin A upon mild acid hydrolysis. Both oligosaccharides, IV and X, have been detected for the first time as the components of an antibiotic.
D006868:Hydrolysis; D008745:Methylation; D009844:Oligosaccharides / Q000032:analysis; D012310:Ristocetin / Q000031:analogs & derivatives* / Q000032:analysis / Q000138:chemical synthesis
D009844:Oligosaccharides; D012310:Ristocetin