title: Vitiligo and dysgammaglobulinemia. A case report and family study.
abstract: This report concerns an 8 year old female with vitiligo and dysgammaglobulinemia characterized by absent IgA, very low IgG, and normal IgM. The t-cell immune system was intact but other family members had low levels or absence of IgA. The possible relationship of dysgammaglobulinemia and vitiligo is discussed along with the classification and inheritance of the immune cell defects.
mesh_terms: D000293:Adolescent; D000328:Adult; D000365:Age Determination by Skeleton; D000368:Aged; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D004406:Dysgammaglobulinemia / Q000235:genetics* / Q000276:immunology; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000235:genetics*; D007196:Indiana; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D010375:Pedigree; D012867:Skin / Q000473:pathology; D014820:Vitiligo / Q000235:genetics* / Q000276:immunology
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M