Murine tumor induction by cytomegalovirus.
Cytomegalic inclusion disease can be induced in mice with relative ease. In the study reported here, grandular neoplasms were produced in four mice by means of immunosupression together with large doses of cytomegalovirus. The results of this study suggest that cytomegalovirus may well be an etiologic agent in the formation of salivary gland tumors.
D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D000961:Antilymphocyte Serum / Q000494:pharmacology; D003587:Cytomegalovirus; D003586:Cytomegalovirus Infections / Q000150:complications*; D007109:Immunity / Q000187:drug effects / Q000528:radiation effects; D007165:Immunosuppression Therapy; D008297:Male; D010307:Parotid Neoplasms / Q000209:etiology; D011830:Radiation Effects; D012468:Salivary Gland Neoplasms / Q000209:etiology*; D013363:Submandibular Gland
D000961:Antilymphocyte Serum