The role of the adrenal gland in the lipid accumulation process in the liver of rats bearing an acth and prolactin producing tumor.
The role of the adrenal glands in the development of fatty liver was investigated in rats bearing a transplantable pituitary mammotropic tumor which produces large quantities of ACTH and prolactin. The biochemical and histochemical and histochemical evidence obtained has demonstrated that the adrenal glands, particularly glucocorticoids, are essential for lipid accumulation in the liver of rats with tumor.
D000311:Adrenal Glands / Q000503:physiopathology*; D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D000818:Animals; D005234:Fatty Liver / Q000209:etiology*; D005260:Female; D005938:Glucocorticoids / Q000378:metabolism; D008055:Lipids / Q000032:analysis; D008099:Liver / Q000032:analysis; D009368:Neoplasm Transplantation; D009384:Paraneoplastic Endocrine Syndromes / Q000150:complications; D010911:Pituitary Neoplasms / Q000150:complications*; D011388:Prolactin / Q000378:metabolism; D051381:Rats; D011916:Rats, Inbred F344
D005938:Glucocorticoids; D008055:Lipids; D000324:Adrenocorticotropic Hormone; D011388:Prolactin