[Role of DNA repair disorders in chromosome instability, decreased longevity and neoplastic cell transformation in hereditary human diseases].
D000741:Anemia, Aplastic / Q000378:metabolism; D001260:Ataxia Telangiectasia / Q000378:metabolism; D002273:Carcinogens / Q000633:toxicity; D002470:Cell Survival; D002490:Central Nervous System / Q000503:physiopathology; D002869:Chromosome Aberrations; D002906:Chromosomes, Human, 6-12 and X; D004260:DNA Repair; D004314:Down Syndrome / Q000378:metabolism; D005148:Facial Dermatoses / Q000378:metabolism; D030342:Genetic Diseases, Inborn / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology; D006801:Humans; D007109:Immunity; D009154:Mutation; D009369:Neoplasms / Q000150:complications; D011371:Progeria / Q000378:metabolism; D012306:Risk; D013577:Syndrome; D014314:Trisomy; D014983:Xeroderma Pigmentosum / Q000378:metabolism
D002273:Carcinogens
Rol' narusheniia reparatsii DNK v nestabil'nosti khromosom, snizhenii zhiznesposobnosti i opukholevoĭ transformatsii kletok pri nasledstvennykh zabolevaniiakh cheloveka.