title: Active transport of sodium by the malpighian tubules of the tsetse fly Glossian morsitans.
abstract: Isolated Malpighian tubules of Glossina morsitans are able to transport sodium against its concentration gradient. Their rate of secretion is dependent on the sodium concentration of the bathing medium. Potassium must be present in the bathing solution for rapid secretion to be maintained, but it does not play an active role in fluid secretion. Lithium and ammonium ions are able to substitute partially for sodium, other monovalent cations cannot. Ouabain does not affect rapid secretion by Glossina tubules in vitro. Conclusions drawn from the results are incorporated into a model of Malpighian tubule cell function in this insect.
mesh_terms: D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D002414:Cations, Monovalent / Q000494:pharmacology; D002988:Cloaca / Q000378:metabolism*; D000242:Cyclic AMP / Q000494:pharmacology; D004231:Diuresis / Q000187:drug effects; D066298:In Vitro Techniques; D008317:Malpighian Tubules / Q000378:metabolism*; D010042:Ouabain / Q000494:pharmacology; D011188:Potassium / Q000494:pharmacology; D012964:Sodium / Q000378:metabolism*; D014370:Tsetse Flies
chemical_list: D002414:Cations, Monovalent; D010042:Ouabain; D012964:Sodium; D000242:Cyclic AMP; D011188:Potassium