[The diagnostic value of various stiffness indices in the evaluation of the diastolic properties of the left ventricle].
The results are presented of simulated calculations obtained with the aid of a continuum model of the left ventricle in a passive state on the basis of a nonlinear elasticity theory. Various empirical indexes of left ventricular rigidity are calculated from modelled diastolic pressure/volume curves, and are compared with myocardial elasticity indicators. With respect to sensitivity and specificity, as the best there were found the volume-standardized Diamond index (d[lnP]/dV)V0 and the Laird index d(lnP)/d/lnV). The indexes are calculated from two parts of enddiastolic pressure/volume values. An analysis of clinically measured values confirmed the model predictions.
D001794:Blood Pressure; D002306:Cardiac Volume; D006332:Cardiomegaly / Q000503:physiopathology; D003971:Diastole; D004548:Elasticity; D006333:Heart Failure / Q000503:physiopathology; D006801:Humans; D008955:Models, Cardiovascular; D009203:Myocardial Infarction / Q000175:diagnosis*; D011379:Prognosis; D016276:Ventricular Function
Zum diagnotischen Aussagewert verschiedener Steifheitsindizes bei der Beurteilung der diastolischen Eigenschaften des linken Ventrikels.