Mitogen-induced suppressor T cell activity in the in vitro cellular immune response.
A 24 h preincubation of human peripheral lymphocytes (PBL) in the presence of phytohemagglutinin (PHA) or concanavalin A (Con. A) renders them suppressive for the response of untreated cells to PHA, Con. A, candidin and allogeneic cells. However, cells stimulated with lipopolysaccharide (LPS) show no suppression.
D003208:Concanavalin A / Q000494:pharmacology; D006801:Humans; D007111:Immunity, Cellular; D008070:Lipopolysaccharides / Q000494:pharmacology; D007959:Lymphocyte Culture Test, Mixed; D008934:Mitogens / Q000494:pharmacology*; D008937:Mitomycins / Q000494:pharmacology; D010835:Phytohemagglutinins / Q000494:pharmacology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
D008070:Lipopolysaccharides; D008934:Mitogens; D008937:Mitomycins; D010835:Phytohemagglutinins; D003208:Concanavalin A