title: Trigeminal neuropathy with nasal ulceration: report of two cases and one necropsy.
abstract: Two cases are reported of progressive trigeminal neutopathy with nasal ulceration. One patient developed signs of spinal cord involvement 15 years after the onset of trigeminal symptoms and died after a total course of 21 years. Necropsy revealed an unusual trigeminospinal system degeneration with deposition of amyloid-like substances in the affected structures. The other patient is alive eight years after the onset of symptoms, the only indication of a lesion outside the trigeminal nerve being a patch of numbness in one leg.
mesh_terms: D000328:Adult; D005260:Female; D005727:Ganglia, Spinal / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009668:Nose Diseases / Q000150:complications*; D010523:Peripheral Nervous System Diseases / Q000150:complications / Q000473:pathology; D012883:Skin Ulcer / Q000150:complications*; D013116:Spinal Cord / Q000098:blood supply / Q000473:pathology; D014276:Trigeminal Nerve / Q000473:pathology