[Selection of cell lines resistant to ouabain from murine plasmacytoma MOPC 173. Cross resistance to cyclic AMP, theophylline, and concanavalin A].
Using ouabain as a selective agent, we obtained from a contact inhibited and a non contact inhibited cell layer derived from the same plasmocytoma, different resistant cell lines. All of them were ouabain resistant but were also able to grow in presence of normallly toxic levels of cAMP, theophylline and concanavalin A.
D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D002462:Cell Membrane / Q000187:drug effects; D003208:Concanavalin A / Q000494:pharmacology; D000242:Cyclic AMP / Q000494:pharmacology; D004351:Drug Resistance; D010042:Ouabain / Q000494:pharmacology; D010954:Plasmacytoma; D013806:Theophylline / Q000494:pharmacology
D003208:Concanavalin A; D010042:Ouabain; D013806:Theophylline; D000242:Cyclic AMP
Sélection de lignées cellulaires résistantes à l'ouabaïne issues du plasmocytome murin MOPC 173. Résistance croisée à l'égard de l'AMP cyclique, de la théophylline et de la concanavaline A