title: Management of the uninhibited bladder by selective sacral neurectomy.
abstract: The authors report the treatment of incontinence due to uninhibited bladder contractions by selective sacral neurectomy in nine patients, four without evidence of neurological disease. A detailed and objective analysis of bladder and urethral function, together with quantitation of clinical features, was made before and after operation. Seven patients were either cured or greatly improved. The overall increase in bladder capacity and reduction of uninhibited activity were statistically significant. The resting urethral sphincter pressure was unchanged, but the contractility of the voluntary external sphincter was slightly impaired. Criteria for such neurectomies are discussed.
mesh_terms: D000763:Anesthesia, Caudal; D000772:Anesthesia, Local; D002045:Bupivacaine; D003714:Denervation; D004775:Enuresis / Q000601:surgery; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D006874:Hydrostatic Pressure; D007796:Laminectomy; D007989:Libido; D008160:Lumbosacral Plexus / Q000601:surgery; D008297:Male; D009119:Muscle Contraction; D009407:Nerve Block / Q000379:methods; D013126:Spinal Nerve Roots / Q000601:surgery*; D009435:Synaptic Transmission; D014521:Urethra / Q000294:innervation; D001743:Urinary Bladder / Q000294:innervation; D001750:Urinary Bladder, Neurogenic / Q000601:surgery*; D014549:Urinary Incontinence / Q000601:surgery*
chemical_list: D002045:Bupivacaine