Dimethylthiourea, an unexpected hazard for textile workers.
Our patient was a 24-year-old female textile cutter who had a conjunctivitis and an erythematous itching dermatitis of the eyelids, nasal mucous membranes, and the corners of the mouth. The patch tests with the standard series and a pharmaceutical test battery were negative. Further epicutaneous testing revealed a strong positive reaction to the textile cutting patterns she handled, which were duplicated by diazo processing. Specifically, the contact dermatitis reaction was caused by dimethylthiourea, an additive in diazo-sensitized paper.
D000328:Adult; D003231:Conjunctivitis / Q000139:chemically induced; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000139:chemically induced*; D005260:Female; D006801:Humans; D013783:Textile Industry; D013890:Thiourea / Q000009:adverse effects / Q000031:analogs & derivatives*
D013890:Thiourea