Giant platelets and fibrin-like inclusions in platelets of BALB/c mice after intraperitoneal inoculation of HIPA tumour agent.
2 days after ip inoculation of cell-free extracts of HIPA tumour, giant platelets and platelets with band-like inclusions were found in blood of BALB/c mice. Band-like inclusions with platelets have morphologic structure of fibrin. Their presence in the thrombocytes is probably an accidental finding. Giant platelets in the circulating blood are probably due to a disturbed meagacaryocytopoiesis.
D000818:Animals; D001792:Blood Platelets / Q000032:analysis / Q000648:ultrastructure*; D002474:Cell-Free System; D005337:Fibrin / Q000032:analysis*; D002479:Inclusion Bodies; D007274:Injections, Intraperitoneal; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental; D010954:Plasmacytoma / Q000032:analysis / Q000473:pathology*; D010974:Platelet Aggregation; D013921:Thrombocytopenia
D005337:Fibrin