[Stimulation of SV40 virus replication in Chinese hamster kidney cells by treatment of the cells with mitomycin C].
The production of virions by Chinese hamster kidney cells infected with SV 40 DNA is increased 10 to 100 fold by mitomycin C treatment. This observation has been confirmed for different cell clones. The optimum concentration of mitomycin C has been determined.
D002460:Cell Line; D004279:DNA, Viral / Q000378:metabolism*; D008937:Mitomycins / Q000494:pharmacology*; D013539:Simian virus 40 / Q000254:growth & development*; D013268:Stimulation, Chemical; D013997:Time Factors; D014779:Virus Replication / Q000187:drug effects*
D004279:DNA, Viral; D008937:Mitomycins
Stimulation de la réplication du virus SV 40 dans des cellules de rein de hamster chinois par traitement de ces cellules avec la mitomycine C