[Immediate effects of desoxycorticosterone of vasomotor properties of noradrenaline and isoprenaline in rats].
In the rat, desoxycorticosterone (3 to 10 mg p. kg) does not modify the systemic vasoconstriction provoked by noradrenaline even in presence of an excess of sodium chloride. This mineralo-steroid reduces the vasodilatation induced by isoprenaline. Sodium chloride in excess potentiates this inhibition.
D000818:Animals; D002339:Carotid Arteries; D003900:Desoxycorticosterone / Q000494:pharmacology*; D005260:Female; D006973:Hypertension / Q000139:chemically induced / Q000503:physiopathology; D007545:Isoproterenol / Q000494:pharmacology*; D007601:Jugular Veins; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology*; D051381:Rats; D012965:Sodium Chloride / Q000494:pharmacology; D014661:Vasoconstriction / Q000187:drug effects*; D014664:Vasodilation / Q000187:drug effects*
D003900:Desoxycorticosterone; D012965:Sodium Chloride; D007545:Isoproterenol; D009638:Norepinephrine
Effets immédiats de la désoxycorticostérone sur les propriétés vasomotrices de la noradrénaline et de l'isoprénaline chez le rat.