Thermal transitions in human plasma low density lipoproteins.
Thermal analysis of human plasma low density lipoproteins reveals a broad reversible transition encompassing body temperature. The calorimetric and x-ray scattering data identify this transition as a cooperation, liquid-crystalline to liquid phase change involving the cholesterol esters in the lipoprotein. This behavior requires the presence of a region rich in cholesterol ester within the lipoprotein.
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002784:Cholesterol / Q000032:analysis; D002788:Cholesterol Esters / Q000032:analysis; D006801:Humans; D008079:Lipoproteins, VLDL / Q000032:analysis / Q000097:blood*; D010743:Phospholipids / Q000032:analysis; D013329:Structure-Activity Relationship; D013696:Temperature; D013816:Thermodynamics; D014280:Triglycerides / Q000032:analysis
D002788:Cholesterol Esters; D008079:Lipoproteins, VLDL; D010743:Phospholipids; D014280:Triglycerides; D002784:Cholesterol