title: Morphine abstinence is associated with increased brain cyclic AMP.
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology / Q000378:metabolism*; D001923:Brain Chemistry / Q000187:drug effects; D003994:Bucladesine / Q000494:pharmacology; D000242:Cyclic AMP / Q000378:metabolism* / Q000494:pharmacology; D006152:Cyclic GMP / Q000494:pharmacology; D003864:Depression, Chemical; D004195:Disease Models, Animal; D004343:Drug Implants; D006801:Humans; D008297:Male; D009020:Morphine / Q000008:administration & dosage; D009021:Morphine Dependence / Q000378:metabolism*; D009043:Motor Activity / Q000187:drug effects; D009270:Naloxone / Q000494:pharmacology; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D051381:Rats; D013268:Stimulation, Chemical; D013375:Substance Withdrawal Syndrome / Q000378:metabolism*
chemical_list: D004343:Drug Implants; D009270:Naloxone; D003994:Bucladesine; D009020:Morphine; D000242:Cyclic AMP; D010727:Phosphoric Diester Hydrolases; D006152:Cyclic GMP