[Spin-labeled nucleosides, nucleoside-5'-mono-, di-, and triphosphates].
A general method of synthesis of spin-labeled nucleosides, nucleoside-5'-mono-, di- and triphosphates is developed. It is based on the acyllation of ribose OH-group with N-(2,2,5,5-tetramethyl-3-carbonylpyrollin-1-oxyl)-imidasole. Their ESR and UV-spectra are studied. While studying the products of interaction between nucleoside mono-, di- and triphosphates and N-(2,2,5,5-tetramethyl-3-carbonylpyrrolin-1-oxyl)-imidasole along with the formation of monoradicals due to the acyllation of 2'(3')-OH-groups of ribose in the case of AMP, GMP and GDP acyllation by the phosphate group with the formation of biradicals has been also observed.
D003497:Cyclic N-Oxides; D004578:Electron Spin Resonance Spectroscopy; D009705:Nucleosides; D009711:Nucleotides; D013113:Spin Labels
D003497:Cyclic N-Oxides; D009705:Nucleosides; D009711:Nucleotides; D013113:Spin Labels
Spin-mechenye nukleozidy, nukleozid-5'-mono-, di- i trifosfaty