title: Absence of poly (A) from the infective RNA of Nodamura virus.
abstract: With the exception of phage Qbeta, the RNAs of all the other small icosahedral RNA viruses so far examined contain a poly (A) tract. This tract has been implicated in the infectivity of poliovirus RNA. We have now shown that Nodamura virus, a divided genome virus from which infective RNA can be extracted, does not contain any poly (A) tracts. This evidence with Nodamura virus shows that poly (A) is not a necessary requirement for the infectivity of virus RNA molecules.
mesh_terms: D005537:Aphthovirus / Q000032:analysis; D010849:Picornaviridae / Q000032:analysis* / Q000472:pathogenicity; D017955:Poliovirus / Q000032:analysis; D011061:Poly A / Q000032:analysis*; D012367:RNA, Viral / Q000032:analysis*
chemical_list: D012367:RNA, Viral; D011061:Poly A