[Demonstration of nucleotide pyrophosphatase and phosphohydrolase activities in normal lymphocyte of Balb/c mice and absence of these activities in YC8 tumor cells and in lymphocytes of animals with YC8 lymphoma].
Saline extraction of tumor cells from YC8 lymphoma transplanted in Balb/c Mice, of lymphocytes from animals bearing this tumor and of lymphocytes from control animals, allowed us to show important hydrolytic activities towards UDP-[(14C)]-galactose and galactose-[(14C)]-1-phosphate in normal lymphocytes. These activities disappear in lymphocytes from Mice bearing this tumor and in tumor cells themselves.
D000818:Animals; D007700:Kinetics; D008214:Lymphocytes / Q000201:enzymology*; D008223:Lymphoma / Q000201:enzymology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009374:Neoplasms, Experimental / Q000201:enzymology; D010744:Phosphoric Monoester Hydrolases / Q000032:analysis*; D011755:Pyrophosphatases / Q000032:analysis*; D014531:Uridine Diphosphate Galactose / Q000378:metabolism
D014531:Uridine Diphosphate Galactose; D010744:Phosphoric Monoester Hydrolases; D011755:Pyrophosphatases
Mise en évidence d'activités nucléotide-pyrophosphatase et phosphohydrolase dans les lymphocytes normaux de Souris Balb/c et absence de ces activités dans les cellules tumorales YC8 et les lymphocytes d'animaux proteurs du lymphome YC8