title: [Granulocyte dysfunction. I. Inborn defects (author's transl)].
abstract: The insight in the function and dysfunction of granulocytes lately arouses more and more interest. This report summarises our present knowledge. In the first of two chapters the authors review the molecular basis of granulocyte function and the inborn defects of chemotaxis, opsonisation, phagocytosis and intracellular killing of bacteria and fungi.
mesh_terms: D000380:Agranulocytosis; D002462:Cell Membrane; D002609:Chediak-Higashi Syndrome / Q000503:physiopathology; D002633:Chemotaxis; D002648:Child; D004314:Down Syndrome / Q000503:physiopathology; D006098:Granulocytes / Q000378:metabolism; D006105:Granulomatous Disease, Chronic / Q000151:congenital / Q000235:genetics; D006402:Hematologic Diseases / Q000151:congenital*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000097:blood; D007589:Job Syndrome / Q000503:physiopathology; D007962:Leukocytes; D009895:Opsonin Proteins / Q000378:metabolism; D009195:Peroxidase / Q000172:deficiency; D010587:Phagocytosis; D014405:Tuftsin / Q000172:deficiency
chemical_list: D009895:Opsonin Proteins; D009195:Peroxidase; D014405:Tuftsin
vernacular_title: Granulocytendyfunktion. I. Angeborene Störungen