Fever, lethargy and rash complicating treatment for Wilms' tumor-a new syndrome?
A syndrome of fever, lethargy, irritability and rash occurred in patients undergoing surgery, irradiation and chemotherapy for Wilms' tumor. The incidence, course and severity of these findings are described. Potential etiologic factors are analyzed and a hypothesis advanced.
D002648:Child; D002675:Child, Preschool; D003609:Dactinomycin / Q000009:adverse effects*; D003872:Dermatitis / Q000209:etiology*; D003875:Drug Eruptions / Q000209:etiology; D005260:Female; D005334:Fever / Q000209:etiology*; D006801:Humans; D007223:Infant; D007239:Infections / Q000150:complications; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D008297:Male; D011183:Postoperative Complications; D011878:Radiotherapy / Q000009:adverse effects*; D013577:Syndrome; D014750:Vincristine / Q000009:adverse effects; D009396:Wilms Tumor / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*
D003609:Dactinomycin; D014750:Vincristine