Glomerular localization of preformed immune complexes in nephrotoxic serum nephritis.
Pre-formed immune complexes solubilized in antigen excess were infused into rats with nephrotoxic serum nephritis and normal control animals. Complex localization was evident in seven of ten nephrotoxic animals suggesting that the presence of immune mediated glomerular injury makes the kidney susceptibility to further immune injury.
D000818:Animals; D000936:Antigen-Antibody Complex; D006041:Goats / Q000276:immunology; D007678:Kidney Glomerulus / Q000032:analysis; D008297:Male; D009393:Nephritis / Q000209:etiology / Q000276:immunology*; D051381:Rats
D000936:Antigen-Antibody Complex