[A histochemical study of the effect of progesterone on the carbohydrate metabolism enzymes of different morphologic forms of endometrial cancer].
The histochemical method was used for determining glycogen, phosphorylase, glycogensynthetase, and glucose-6-phosphatase in order to evaluate the effect of progesterone on different morphological forms of cancer of the endometrium in man. On the basis of histochemical analysis of changes in the carbohydrate metabolism in 29 cases of cancer before and after treatment with progesterone a conclusion is drawn that sensitivity of tumours of the endometrium to hormonotherapy only partially depends upon the degree of their morphological differentiation.
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000201:enzymology; D002277:Carcinoma / Q000188:drug therapy* / Q000201:enzymology; D005260:Female; D005952:Glucose-6-Phosphatase / Q000378:metabolism; D006006:Glycogen Synthase / Q000378:metabolism; D006651:Histocytochemistry; D006801:Humans; D006908:Hydroxyprogesterones / Q000627:therapeutic use*; D014594:Uterine Neoplasms / Q000188:drug therapy* / Q000201:enzymology
D006908:Hydroxyprogesterones; D006006:Glycogen Synthase; D005952:Glucose-6-Phosphatase
Gistokhimicheskoe issledovanie deĭstviia progesterona na fermenty uglevodnogo obmena razlichnykh morfologicheskikh form raka éndometriia