[Cytomegalovirus antibodies in the pregnant female and in the newborn infant complement fixation and indirect hemagglutination tests (author's transl)].
705 paired sera from mother and infant have been studied at the time of the child birth for the presence of cytomegalovirus antibodies by complement-fixation and indirect hemagglutination tests. 51.3% of those sera were found to have CF antibodies, and 72.8% to have HA antibodies. The indirect hemagglutination test is a more sensitive reaction and detects also IgM antibodies. Chosen sera were fractionated and searched for IgM-HA antibodies to detect CMV congenital infections; only one child was found to be positive. The number of mothers having been in contact with cytomegalovirus was 82.7% (having CF or HA antibodies or both). Immigrant were found to be more often positive than native women (94.3% vs 76.1%); this difference was even greater when CF antibodies alone were considered (74.6% vs 37.7%). Depending on age groups of mothers, the increased number of positives found in CF test was not noticed in HA test.
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral; D000917:Antibody Formation; D003168:Complement Fixation Tests; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000276:immunology; D005260:Female; D006387:Hemagglutination, Viral; D006801:Humans; D007074:Immunoglobulin G / Q000302:isolation & purification; D007075:Immunoglobulin M / Q000302:isolation & purification; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D044469:Racial Groups
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Cytomégalovirus et anticorps foeto-maternels: Etude comparée des réactions de fixation du complément et d'hémagglutination indirecte