title: Oxamethacin: a pilot field survey.
abstract: Two hundred sixty-four general practice patients were treated with oxamethacin (100 mg b.i.d.) and 261 with indomethacin (50 mg b.i.d.) for a maximum period of two weeks. Both drugs showed equally good analgesic and anti-inflammatory effects. Thirty-six patients (14%) treated with oxamethacin and sixty patients (23%) treated with indomethacin reported side-effects. Among them, seventeen patients on oxamethacin (6%) and forty-tree patients on indomethacin (16.5%) reported gastro-intestinal disorders. Side-effects necessitated interruption of treatment in fourteen patients (5%) on oxamethacin and in thirty-three patients (13%) on indomethacin.
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001168:Arthritis / Q000188:drug therapy; D001416:Back Pain / Q000188:drug therapy; D006073:Gout / Q000188:drug therapy; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D052256:Tendinopathy / Q000188:drug therapy
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; C019028:oxamethacin; D007213:Indomethacin