[Study of the interrelationship between the content of immunizing units and the immunogenicity of C1. perfringens anatoxins].
Comparative experiments were conducted on rabbits and guinea pigs; a study was made of the immunological efficacy of the toxoids with a different content of the immunizing units (IU/ml). There was revealed a regular quantitative interrelationship between the content of the IU/ml in the toxoids, the level of the antitoxin formation and the extent of protection against the experimental gas gangrene in the immunized animals.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000917:Antibody Formation / Q000187:drug effects*; D000942:Antigens, Bacterial / Q000032:analysis; D003016:Clostridium perfringens / Q000276:immunology*; D004353:Drug Evaluation, Preclinical; D005738:Gas Gangrene / Q000276:immunology / Q000401:mortality; D006168:Guinea Pigs; D007114:Immunization; D007117:Immunization, Secondary; D011817:Rabbits; D013997:Time Factors; D014121:Toxoids / Q000032:analysis
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D014121:Toxoids
Izuchenie vzaimosviazi mezhdu soderzhaniem immuniziruiushchikh edinitis i immunogennost'iu anatoksinov C1. perfringens