Lymphocyte-associated antigens in patients with alveolar cell carcinoma.
Antiserum produced in rabbits against a virus-like particle pellet recovered from human alveolar cell carcinoma (ACC) was used for the detection of lymphocyte-associated antigen in patients with ACC. The method used was direct immunofluorescence. The results demonstrate that lymphocytes from some patients with ACC possess antigen and the presence of lymphocyte fluorescence in patients with ACC suggests widespread or metastatic disease. The presence of antigen may be of both diagnostic and prognostic value.
D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000276:immunology*; D000818:Animals; D000951:Antigens, Neoplasm / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007106:Immune Sera; D066298:In Vitro Techniques; D008175:Lung Neoplasms / Q000276:immunology*; D008177:Lupus Vulgaris / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D009362:Neoplasm Metastasis; D009393:Nephritis / Q000276:immunology; D011817:Rabbits
D000951:Antigens, Neoplasm; D007106:Immune Sera