Lack of effect of prolactin suppression on plasma dehydroepiandrosterone sulphate.
In twelve patients with hyperprolactinaemia, treatment which reduced plasma prolactin from a mean of 531 microgram/l (range 68-3500 microgram/1) to 8.3 microgram/l (0-27 microgram/l), caused no significant change in plasma dehydroepiandrosterone sulphate (DHA-SO4). Pre-treatment levels of DHA-SO4 were within the normal range in eleven out of twelve cases. The results do not support for claims that prolactin excess is associated with an increase in circulating DHA-SO4.
D000293:Adolescent; D000328:Adult; D003687:Dehydroepiandrosterone / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D011388:Prolactin / Q000097:blood*
D003687:Dehydroepiandrosterone; D011388:Prolactin