title: [Waldenstrôm's macroglobulinemia. Developmental and prognostic study].
abstract: The course of 27 cases of Waldenström's macroglobuilinemia was observed during at least 2 years or until death. A worsening occurred in half of the patients, with 7 deaths before 2 years. 10 patients improved under therapy, with only two deaths later. The more frequent complications were infections, but other complications, haemorragic, neurologic, osseous and renal were also observed. A haemoglobin initial level higher than 9 g % and a significant decrease of lymphocyte blood count under chemotherapy seem to be of good prognosis.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D008258:Waldenstrom Macroglobulinemia / Q000150:complications / Q000401:mortality
chemical_list: D007075:Immunoglobulin M
vernacular_title: Macroglobulinémie de Waldenström. Etude évolutive et pronostique