title: Effects of rate of repetitive stimulus presentation on the visual evoked brain potentials of young adults with Down's syndrome.
abstract: Visual evoked brain potentials (VEP) to repeated stimuli of several interstimulus intervals (ISI) were recorded from young adults with Down's syndrome (DS). The following results were obtained: (i) An ISI effect previously observed in normals: VEP amplitudes increased with increase in ISI; some ISI effect on latency was also observed; (ii) VEP amplitudes of DS subjects were larger than VEP amplitudes of normals; (iii) VEP peak latencies of DS subjects were longer than VEP peak latencies obtained from normals; (iv) ISI had a more pronounced effect on VEP amplitudes of DS than normal subjects. These results are discussed with respect to CNS differences and issues of attention and information processing.
mesh_terms: D000328:Adult; D002540:Cerebral Cortex / Q000502:physiology; D004314:Down Syndrome / Q000523:psychology*; D004569:Electroencephalography; D005071:Evoked Potentials; D006801:Humans; D008297:Male; D010775:Photic Stimulation / Q000379:methods; D011930:Reaction Time / Q000502:physiology; D014796:Visual Perception / Q000502:physiology