title: [Studies on the Relationship between immunity and the level of neutralizing antibodies in pigs vaccinated against foot-and-mouth disease (author's transl)].
abstract: The statistical relationship between the titers of neutralizing antibodies and the immunity of 706 pigs vaccinated against FMD was studied. This was done for each of four virus strains separately. Whereas no correlation between both test systems could be detected in case of the strains A5 Westerwald, C Detmold and O1Santander, a significant correlation was ascertained for the strain O1Kaufbeuren. Becuase of the different findings depending on the virus strain under study it was concluded that the antibody titer alone does not provide a useful measure for potency testing of FMD-vaccines for pigs.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D005537:Aphthovirus / Q000276:immunology*; D005536:Foot-and-Mouth Disease / Q000276:immunology* / Q000517:prevention & control; D007109:Immunity; D009500:Neutralization Tests; D013552:Swine; D013553:Swine Diseases / Q000276:immunology* / Q000517:prevention & control; D014611:Vaccination / Q000662:veterinary; D014765:Viral Vaccines
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines
vernacular_title: Untersuchungen zur Abhängigkeit zwischen immunität und Höhe der Neutralisationstiter bei Schweinen nach Impfung mit Maul- und Klauenseuche-(MKS-)Vakzinen