Enhancement of attention in man with ACTH/MSH 4-10.
Normal men were infused for 4 hr with ACTH/MSH 4-10 or a control solution. Behavioral testing after the infusion indicated that subjects who received ACTH/MSH 4-10 were less anxious and had better visual memory than control subjects but the predominant effect of the heptapeptide was to increase visual attention. It was speculated that ACTH/MSH 4-10 may be uniquely coded for attentional functioning.
D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives / Q000494:pharmacology*; D000328:Adult; D001143:Arousal / Q000187:drug effects; D001288:Attention / Q000187:drug effects*; D006801:Humans; D008297:Male; D009074:Melanocyte-Stimulating Hormones / Q000031:analogs & derivatives / Q000494:pharmacology*; D008568:Memory / Q000187:drug effects; D010455:Peptides / Q000494:pharmacology; D013268:Stimulation, Chemical; D014796:Visual Perception / Q000187:drug effects
D010455:Peptides; D000324:Adrenocorticotropic Hormone; D009074:Melanocyte-Stimulating Hormones