Evaluation of a rapid and simple technique for the radioimmunoassay of triiodothyronine (T3).
This report compares T3 measurements obtained on the same serum samples by a resinstrip technique and by another existing radioimmunoassay method. The samples analyzed were obtained from a total of 90 subjects who were clinically categorized as hypothyroid, normal, hyperthyroid, or euthyroid while taking estrogen-containing compounds or while pregnant. The correlation coefficient for all 90 sera with these two different techniques was 0.94. All subjects who were clinically euthyroid (32) had a normal serum T3 concentration by the resin-strip technique. Similarly, 23 clinically hyperthyroid patients had elevated serum T3 concentrations and 15 of 17 clinically hypothyroid patients had decreased serum T3 levels.
D003271:Contraceptive Agents, Female / Q000494:pharmacology; D004966:Estrogens, Conjugated (USP) / Q000494:pharmacology; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000175:diagnosis; D007037:Hypothyroidism / Q000175:diagnosis; D011247:Pregnancy; D011863:Radioimmunoassay / Q000379:methods*; D013961:Thyroid Gland / Q000187:drug effects; D014284:Triiodothyronine / Q000097:blood*
D003271:Contraceptive Agents, Female; D004966:Estrogens, Conjugated (USP); D014284:Triiodothyronine