PPD-induced blastogenesis is auto-regulated by suppressor cells generated in vitro.
Suppressor cell induction can be demonstrated during antigen specific blastogenesis by using the same methods which have shown induction of suppressor cells by Con A. Since suppressor cells are rapidly generated during antigen specific blastogenesis, they must regulate the final level of blastogenesis induced during the seven day in vitro incubation.
D003208:Concanavalin A; D004305:Dose-Response Relationship, Drug; D006801:Humans; D037102:Lectins; D008213:Lymphocyte Activation; D009000:Monocytes / Q000187:drug effects / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects / Q000276:immunology*; D014373:Tuberculin
D037102:Lectins; D014373:Tuberculin; D003208:Concanavalin A