title: Inclusion bodies in brain cell cultures from Creutzfeldt-Jakob disease.
abstract: Brain cell cultures were established from 20 patients with various forms of dementia and studied for evidence of virus induced alterations. Changes were detected in the cultured cells from 1 patient (L.C.) with the clinical and pathological diagnosis of Creutzfeldt-Jakob disease. These changes were present in the early passages of the brain tissue and were not seen in the cultures from the other cases.
mesh_terms: D002467:Cell Nucleus; D007562:Creutzfeldt-Jakob Syndrome / Q000473:pathology*; D046508:Culture Techniques; D006801:Humans; D002479:Inclusion Bodies; D013997:Time Factors