Binding of testosterone, dihydrotestosterone and progesterone to rat prostate cytosol: application of microcalorimetry.
The binding capacity of rat prostate cytosol for dihydrotestosterone, testosterone and progesterone was studied in vitro. The thermodynamic parameters obtained by microcalorimetry point to the importance of the observation of energy changes occuring during the hormone-receptor complex formation.
D000818:Animals; D001665:Binding Sites; D002151:Calorimetry; D002369:Castration; D003600:Cytosol / Q000378:metabolism*; D013196:Dihydrotestosterone / Q000378:metabolism*; D008297:Male; D011374:Progesterone / Q000378:metabolism*; D011467:Prostate / Q000378:metabolism*; D051381:Rats; D011956:Receptors, Cell Surface; D013739:Testosterone / Q000378:metabolism*
D011956:Receptors, Cell Surface; D013196:Dihydrotestosterone; D013739:Testosterone; D011374:Progesterone