Reversible modification of rat liver F1-ATPase by a redox reaction.
F1-ATPase from rat liver mitochondria exhibited a change in properties when reduced by dithionite: an increase in activity together with a disappearance of its sensitivity to bicarbonate stimulation was observed. A complete reversion to the original properties was achieved with the oxidizing agent 2,6-dichlorophenolindophenol.
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology; D002614:Chelating Agents / Q000494:pharmacology; D004227:Dithionite / Q000378:metabolism* / Q000494:pharmacology; D004789:Enzyme Activation; D008930:Mitochondria, Liver / Q000201:enzymology*; D010084:Oxidation-Reduction; D051381:Rats; D013447:Sulfites / Q000378:metabolism*
D001639:Bicarbonates; D002614:Chelating Agents; D013447:Sulfites; D004227:Dithionite; D000251:Adenosine Triphosphatases