Heat-accelerated radioinactivation of attenuated poliovirus.
Attenuated poliovirus is inactivated in a synergistic manner when exposed simultaneously to heat and ionizing radiation. The synergistic response is observed in both the thermally labile and stable forms of the virus. A three-term kinetic model may be used to describe the inactivation response of the virus in a thermal and/or ionizing radiation environment.
D003037:Cobalt Radioisotopes; D005720:Gamma Rays; D006358:Hot Temperature; D017955:Poliovirus / Q000528:radiation effects; D011830:Radiation Effects
D003037:Cobalt Radioisotopes