Togavirus-like particles in renal epithelium of patients with systemic lupus erythematosus.
Virus-like particles, about 45 nm in diameter, were present in renal epithelium (tubules and podocytes) of 12 patients with confirmed systemic lupus erythematosus (SLE) and in 2 patients with probable SLE. They were not detected in renal biopsies from non-SLE patients. Morphologically, they suggest togavirus-like particles.
D001103:Arboviruses; D001706:Biopsy; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure; D007668:Kidney / Q000382:microbiology / Q000473:pathology / Q000648:ultrastructure*; D007684:Kidney Tubules / Q000648:ultrastructure; D008180:Lupus Erythematosus, Systemic / Q000473:pathology*; D008297:Male