Limitation of the specific serum radioimmunoassay for human chorionic gonadotropin in the management of trophoblastic neoplasms.
Two cases of recurrent trophoblastic disease are presented in which human chorionic gonadotropin was detected in assays of urine concentrates at a time when serum levels were undetectable by a sensitive and specific beta-subunit radioimmunoassay. The potential greater usefulness of measurements of urinary concentrates is discussed.
D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood* / Q000652:urine; D005260:Female; D006801:Humans; D011247:Pregnancy; D011863:Radioimmunoassay; D012008:Recurrence; D014328:Trophoblastic Neoplasms / Q000378:metabolism*
D006063:Chorionic Gonadotropin