title: [Effect of daily instillations of timolol on the nycthemeral tension in subjects with chronic open-angle glaucoma (author's transl)].
abstract: This study included 22 patients with chronic open-angle glaucoma who were treated with either 0.25% or 0.5% timolol. The results showed that a single daily instillation of 0.25% or 0.5% timolol was effective, without producing any side-effects. It was interesting to note that timolol caused the tension peaks to disappear, the nycthemeral graph curve becoming plateau-shaped.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D011412:Propanolamines / Q000008:administration & dosage*; D013997:Time Factors; D013999:Timolol / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D011412:Propanolamines; D013999:Timolol
vernacular_title: Action d'une instillation quotidienne de timolol sur la courbe tensionnelle nycthémérale de sujets porteurs d'un glaucome à angle ouvert.