title: Lack of glucose phosphotransferase function in phosphofructokinase mutants of Escherichia coli.
abstract: Phosphofructokinase (pfkA) mutants of Escherichia coli are impaired in growth on all carbon sources entering glycolysis at or above the level of fructose 6-phosphate (nonpermissive carbon sources), but growth is particularly slow on sugars, such as glucose, which are normally transported and phosphorylated by the phosphoenolpyruvate, (PEP)-dependent phosphotransferase system (PTS).
mesh_terms: D004926:Escherichia coli / Q000201:enzymology* / Q000254:growth & development / Q000378:metabolism; D005690:Galactose / Q000378:metabolism; D005941:Glucokinase / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D008358:Mannose / Q000378:metabolism; D009154:Mutation; D010641:Phenotype; D010728:Phosphoenolpyruvate / Q000378:metabolism; D010732:Phosphofructokinase-1 / Q000096:biosynthesis*; D010770:Phosphotransferases / Q000378:metabolism
chemical_list: D010728:Phosphoenolpyruvate; D010770:Phosphotransferases; D010732:Phosphofructokinase-1; D005941:Glucokinase; D005947:Glucose; D008358:Mannose; D005690:Galactose