[The "greifswald-therapy-model" for carcinoma of the cervix uteri for clinical testing of the cancer-multistep-therapy after M. von Ardenne (author's transl)].
The results of a preliminary study of the cancer-Multistep-Therapy (C.M.T.) (so called "The Greifswald-Modell") are reported. This Greifswald-Therapy-Model has been developed by hitherto existing experiences in the clinical test of the C.M.T. 4 patients with carcinoma uteri T2bNOMO to T2bNOMO level epithelium-carcinomas histologically verified showed after a preoperative treatment with C.M.T. and cantactradiatio (60CO) under the employment of a reduced dose of radios (1/2 to 1/3 of the pretherapy used in this clinic or 1/4 to 1/5 of the tumor dose) a complete regression of the tumor-specific changes. In the surgical specimen won after 4-7 weeks after C.M.T., carcinoma could not be detected either macroscopically or microscopically. Patients with a good therapy -- compatibility show a liberty of relapse with an increase in weight and an excellent physical and psychical health two year after C.M.T. This preliminary study shows the capability of the well - chosen therapy-model for the clinical test of the therapy-effect of the C.M.T. and it urgently demands to carry on with adequate alternate rows by including other conventional therapy schemes and other kinds of tumor to estimate definitively the effect of the C.M.T. in the tumor therapy.
D000359:Aftercare; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008722:Methods; D008954:Models, Biological; D011867:Radioisotope Teletherapy; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*
D003037:Cobalt Radioisotopes
Das "Greifswalder Therapiemodell" für das Karzinom der Zervix uteri zur klinischen Prüfung der Krebs-Mehrschritt-Therapie nach M. von Ardenne