Interactions between lymphocytes and C-type oncornaviruses in mice.
Several aspects of C-type oncornavirus-lymphocyte interactions in the mouse are reviewed: 1) immunological abnormalities induced by C-type viruses, particularly immunosuppression and autoimmunity; 2) activation or amplification of endogenous C-type viruses during immunological reactions; and 3) the immune responses to these endogenous oncornaviruses. A unifying hypothesis is proposed to relate various interactions between lymphocytes and C-type oncornaviruses.
D000818:Animals; D000956:Antigens, Viral; D001323:Autoantibodies; D005622:Friend murine leukemia virus / Q000276:immunology; D005796:Genes; D007111:Immunity, Cellular; D007165:Immunosuppression Therapy; D008214:Lymphocytes / Q000276:immunology*; D008223:Lymphoma / Q000276:immunology*; D051379:Mice; D008815:Mice, Inbred Strains; D009374:Neoplasms, Experimental / Q000276:immunology; D012190:Retroviridae / Q000276:immunology*; D014779:Virus Replication
D000956:Antigens, Viral; D001323:Autoantibodies