Some effects of an intrauterine device on glucosaminoglycans of the hamster uterus.
The effect of an intrauterine device (IUD) on non-heparin sulfomucopolysaccharide (SMP) was studied in castrated, hormone-treated, and cycling hamsters by photographic densitometry of tissue sections stained specifically for SMP with Alcian blue. Non-heparin SMP increased slightly in the myometrium of IUD-containing uteri of all castrated groups, with the increase being significant in only the peanut oil-treated group. The endometrium also showed slight increases in sulfomucin in IUD-containing uteri of peanut oil, progesterone, and estrogen plus progesterone-treated animals. These increases, however, were not statistically significant. In cycling hamsters the IUD had little effect on uterine non-heparin SMP in most cycle stages.
D000818:Animals; D010367:Arachis; D002369:Castration; D006224:Cricetinae; D003720:Densitometry; D004967:Estrogens / Q000494:pharmacology; D004971:Estrus; D005260:Female; D006025:Glycosaminoglycans / Q000502:physiology*; D007434:Intrauterine Devices; D009821:Oils / Q000494:pharmacology; D011247:Pregnancy; D011374:Progesterone / Q000494:pharmacology; D014599:Uterus / Q000502:physiology*
D004967:Estrogens; D006025:Glycosaminoglycans; D009821:Oils; C020341:glucosaminoglycans; D011374:Progesterone