title: Evolution of type C viral genes: evidence for an Asian origin of man.
abstract: Old World monkeys and apes, including man, possess, as a normal component of their cellular DNA, gene sequences (virogenes) related to the RNA of a virus isolated from baboons. A comparison of the viral gene sequences and the other cellular sequences distinguishes those Old World monkeys and apes that have evolved in Africa from those that have evolved in Asia. Among the apes, only gorilla and chimpanzee seem by these criteria to be African, whereas gibbon, orang-utan and man are identified as Asian, leading us to conclude that most of man's evolution has occurred outside Africa.
mesh_terms: D000349:Africa; D000595:Amino Acid Sequence; D000818:Animals; D001208:Asia; D005075:Biological Evolution; D004247:DNA / Q000032:analysis; D005796:Genes; D006801:Humans; D009691:Nucleic Acid Denaturation; D009693:Nucleic Acid Hybridization; D010215:Papio / Q000382:microbiology; D011323:Primates / Q000382:microbiology; D012367:RNA, Viral / Q000032:analysis; D012190:Retroviridae; D013045:Species Specificity; D013696:Temperature
chemical_list: D012367:RNA, Viral; D004247:DNA