Study of Pseudomonas haemolysin. II. Characteristics of Pseudomonas haemolysin.
Haemolysins of 4 strains of Pseudomonas aeruginosa producing different fractions [II, 2 + II, I + II + III] were studied. The production of specific antibodies was demonstrated making possible the immunoelectrophoretic record of the whole lysin and of the individual fractions. Tests on laboratory animals [mice, rabbits] showed a high degree lethal and dermonecrotic property of the lysin containing the fractions II + III and I + II + III.
D000042:Absorption; D000818:Animals; D000918:Antibody Specificity; D003091:Colistin / Q000494:pharmacology; D003601:Cytotoxicity Tests, Immunologic; D004586:Electrophoresis; D004912:Erythrocytes / Q000276:immunology; D005839:Gentamicins / Q000494:pharmacology; D006460:Hemolysin Proteins / Q000032:analysis*; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D051379:Mice; D008826:Microbial Sensitivity Tests; D011113:Polymyxins / Q000494:pharmacology; D011549:Pseudomonas / Q000276:immunology*; D011817:Rabbits / Q000276:immunology; D012756:Sheep / Q000276:immunology
D005839:Gentamicins; D006460:Hemolysin Proteins; D011113:Polymyxins; D003091:Colistin