Demonstration of intracellular growth of gonococci in human phagocytes using spectinomycin to kill extracellular organisms.
The use of spectinomycin to kill extracellular bacterial in phagocytosis tests with gonococci and human polymorphonuclear phagocytes allowed the demonstration of a greater degree of intracellular survival and growth than in previous tests using penicillin.
D006801:Humans; D009344:Neisseria gonorrhoeae / Q000187:drug effects / Q000254:growth & development*; D009504:Neutrophils / Q000382:microbiology*; D010587:Phagocytosis; D000198:Spectinomycin / Q000494:pharmacology*
D000198:Spectinomycin