Failure to SV40-transformed lizard cells to induce tumors in autogeneic or allogeneic hosts.
Lizard cells from the tails of geckos were readily morphologically and antigenically transformed in vitro by SV40 virus. Neither autografts of these cells nor allografts of SV40 transformed gecko embryo cells produced tumors in animals under observation for 1 to 3 years.
D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D008116:Lizards; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000473:pathology*; D013539:Simian virus 40; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous