Potential halogenated industrial carcinogenic and mutagenic chemicals. III. Alkane halides, alkanols and ethers.
A variety of alkane halides, alkanols and ethers, analogous to the previously considered halogenated unsaturated (Part I) and saturated hydrocarbons (Part II) possess significant utility in a broad spectrum of applications including: solvents, fumigants, propellants and intermediates in the production of other chemicals, textiles, plastics and ion-exchange resins. Ethylene dichloride and dibromide, propylene dichloride; dibromochloropropane; 2-chloroethanol; 1-chloro-2-propanol; 2,3-dibromo-1-propanol; bis(chloromethyl)-, chloromethyl methyl-, bis(2-chloroisopropyl)-, and bis(2-chloroethyl-ethers were reviewed principally in terms of their synthesis, areas of utility, stability, distribution, reactivity, levels of exposure, population at risk, metabolism, carcinogenicity and mutagenicity.
D000438:Alcohols / Q000633:toxicity; D000473:Alkanes / Q000633:toxicity; D000818:Animals; D001725:Bis(Chloromethyl) Ether / Q000633:toxicity; D002274:Carcinogens, Environmental; D004781:Environmental Exposure; D004987:Ethers / Q000633:toxicity; D005023:Ethylene Chlorohydrin / Q000633:toxicity; D015946:Ethylene Dibromide / Q000633:toxicity; D005025:Ethylene Dichlorides / Q000633:toxicity; D006801:Humans; D006846:Hydrocarbons, Halogenated / Q000633:toxicity*; D008738:Methyl Ethers / Q000633:toxicity; D009153:Mutagens
D000438:Alcohols; D000473:Alkanes; D002274:Carcinogens, Environmental; D004987:Ethers; D005025:Ethylene Dichlorides; D006846:Hydrocarbons, Halogenated; D008738:Methyl Ethers; D009153:Mutagens; D015946:Ethylene Dibromide; D005023:Ethylene Chlorohydrin; D001725:Bis(Chloromethyl) Ether