title: A histochemical study of denervated marsupial hemidiaphragm.
abstract: The marsupial (quokka) hemidiaphragm showed postdenervation hypertrophy and subsequent atrophy. The type II muscle fibres hypertrophied up to 20 days postoperation and then regressed. However, the type I fibres hypertrophied throughout the experimental period (100 days) studied. Unlike denervated eutherian hemidiaphragm, fibre-splitting was absent in the denervated marsupial muscle. An enhancement of the ATPase reaction in the denervated type I fibres may be due to dedifferentiation. Presumably innervation exerts a 'negative control' and prevents increase of type I fibre size in the normal hemidiaphragm.
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D001284:Atrophy; D003714:Denervation; D003964:Diaphragm; D005260:Female; D006984:Hypertrophy; D007614:Macropodidae / Q000033:anatomy & histology*; D008297:Male; D008394:Marsupialia / Q000033:anatomy & histology*; D009132:Muscles / Q000201:enzymology / Q000294:innervation* / Q000473:pathology
chemical_list: D000251:Adenosine Triphosphatases