Avian myeloblastosis virus-induced lymphosarcoma producing erythroblastic leucosis in chicks.
Acute myeloblastosis and several forms of tumor, including one case of lymphosarcoma occurred when avian myeloblastosis virus (BAI-A strain) was inoculated into newly hatched chicks (SPF). The homogenate of lymphosarcoma inoculated intraperitoneally into other newly hatched chicks induced a high incidence of erythroblastic leucosis. Electron microscopy did not reveal the presence of C-type virus particles in the tumor tissue. The relationship between avian myeloblastosis virus, lymphosarcoma and erythroblastic leucosis is discussed.
D000818:Animals; D001353:Avian Leukosis / Q000209:etiology*; D001354:Avian Leukosis Virus / Q000472:pathogenicity; D009189:Avian Myeloblastosis Virus / Q000472:pathogenicity; D001853:Bone Marrow / Q000648:ultrastructure; D001854:Bone Marrow Cells; D002645:Chickens; D006614:Hindlimb; D008228:Lymphoma, Non-Hodgkin / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D009374:Neoplasms, Experimental; D011201:Poultry Diseases / Q000209:etiology*; D012190:Retroviridae / Q000648:ultrastructure; D009396:Wilms Tumor / Q000209:etiology / Q000662:veterinary