[Congenital cytomegalovirus infection after maternal renal transplantation (author's transl)].
A 34-year-old female gave birth to a 32 to 35 week-old girl one year after she had undergone renal transplantation. The child was dwarfed and microcephalic and also had congenital platelet deficiency and purpura. In addition it was anaemic and suffered from severe neonatal icterus. An initial hypogammaglobulinaemia disappeared except for low IgA levels. The immunoglobulin deficiency is probably correlated with the virologically and serologically proven cytomegalovirus infection. The incidence of this disease seems to be high in children of mothers with renal transplantations.
D000361:Agammaglobulinemia / Q000151:congenital; D000751:Anemia, Neonatal / Q000175:diagnosis; D003586:Cytomegalovirus Infections / Q000151:congenital*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000175:diagnosis; D016030:Kidney Transplantation; D008831:Microcephaly / Q000175:diagnosis; D011247:Pregnancy; D011693:Purpura / Q000151:congenital; D013921:Thrombocytopenia / Q000151:congenital; D013997:Time Factors
D007070:Immunoglobulin A
Konnatale Zytomegalie des Kindes einer nierentransplantierten Mutter