[Effect of antibiotics on the resistance of white mice to C1. perfringens toxin].
The effect of potassium benzylpenicillin, streptomycin sulfate and chlortetracycline on experimental gangrenous intoxication was studied. When the antibiotics were injected before intoxication, the albino mice resistance did not significantly change. When the antibiotics were injected immediately after the toxin administration, the resistance of the test animals markedly decreased.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003016:Clostridium perfringens; D004347:Drug Interactions; D004351:Drug Resistance; D005738:Gas Gangrene / Q000188:drug therapy; D051379:Mice; D010406:Penicillins / Q000494:pharmacology; D013307:Streptomycin / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology; D013997:Time Factors; D014118:Toxins, Biological / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D010406:Penicillins; D014118:Toxins, Biological; D013752:Tetracycline; D013307:Streptomycin
Vliianie antibiotikov na ustoĭchivost' belykh mysheĭ k toksinu C1. perfringens