Enhanced SV 40-virus replication in chinese hamster kidney cells pretreated with 5-iodo-2'-deoxyuridine.
SV40 virion production was enhanced when semipermissive Chinese hamster kidney cells were treated with 5-iodo-2'-deoxyuridine (IUDR), prior to infection either with virus or viral-DNA. Pretreatment did not increase SV40 replication in fully permissive monkey kidney and nonpermissive Syrian hamster or mouse embryo cells.
D000956:Antigens, Viral / Q000032:analysis; D002460:Cell Line; D004279:DNA, Viral / Q000096:biosynthesis; D007065:Idoxuridine / Q000494:pharmacology*; D013539:Simian virus 40 / Q000254:growth & development* / Q000276:immunology / Q000378:metabolism; D014779:Virus Replication / Q000187:drug effects*
D000956:Antigens, Viral; D004279:DNA, Viral; D007065:Idoxuridine