title: Herpesvirus infection in the newborn. Its treatment by exchange transfusion and adenosine arabinoside.
abstract: A case is reported of herpesvirus infection in the newborn following maternal genital herpesvirus infection. The rationale for treating a newborn infant with signs of disseminated herpesvirus infection by exchange transfusion in addition to adenosine arabinoside is discussed. Because of the lack of data concerning therapy for a disease with a 50 to 100% mortality rate, it is important to present material such as this in order to provide information about possible new therapeutic modalities.
mesh_terms: D000328:Adult; D005078:Exchange Transfusion, Whole Blood; D005260:Female; D006564:Herpesviridae / Q000302:isolation & purification; D006566:Herpesviridae Infections / Q000188:drug therapy / Q000276:immunology / Q000628:therapy*; D006801:Humans; D007111:Immunity, Cellular; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000628:therapy*; D008297:Male; D011247:Pregnancy; D011684:Purine Nucleosides / Q000627:therapeutic use*; D014740:Vidarabine / Q000627:therapeutic use*
chemical_list: D011684:Purine Nucleosides; D014740:Vidarabine