[Distribution of Mg-activated ATPase activity in the sensorimotor cortex (electron-cytochemical study)].
The localization of Mg-activated ATPase was studied by the lead method. The reaction product was seen in the nuclei and nucleoli of the cells. Five types of its distribution in the nuclei, typical for different types of cells and characterizing their functional activity were distinguished. The reaction to ATPase was also determined in the ribosomes, lipofuscin granules and some oval areas of the cytoplasma of cellular bodies and axons. The precipitate in the brain mitochondria was detected only after the administration of aminazine (15 mg/kg), i. e. in conditions of increased membrane permeability. The presence of ATPase reaction products in axo-dendrite synapses of different types, where it is mainly bound with postsynaptical consolidation and reflects the size of zone activity contacts, may have a direct relation to the conduction of the nervous impulse. The reaction product is also constantly present in the basal membrane of blood vessels.
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D002466:Cell Nucleolus / Q000201:enzymology; D002467:Cell Nucleus / Q000201:enzymology; D002746:Chlorpromazine / Q000494:pharmacology; D004789:Enzyme Activation; D006651:Histocytochemistry; D008274:Magnesium / Q000494:pharmacology*; D008854:Microscopy, Electron; D008928:Mitochondria / Q000201:enzymology; D009044:Motor Cortex / Q000201:enzymology*; D051381:Rats; D013003:Somatosensory Cortex / Q000201:enzymology*; D013569:Synapses / Q000201:enzymology
D000251:Adenosine Triphosphatases; D008274:Magnesium; D002746:Chlorpromazine
Raspredelenie Mg-aktiviruemoĭ ATF-aznoĭ aktivnosti v sensorno-motornoĭ kore golovnogo mozga (élektronno-tsitokhimicheskoe issledovanie).