title: Comedo formation following cobalt irradiation.
abstract: After cobalt-60 therapy 3 patients developed open and closed comedones in the face corresponding to the treatment fields. Biopsies showed extensive dermal elastotic material. It is suggested that the elastotic fibres may contribute to a change in the supporting function of the dermis and a secondary sebum retention and comedo formation.
mesh_terms: D000152:Acne Vulgaris / Q000209:etiology* / Q000473:pathology; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D003037:Cobalt Radioisotopes / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009669:Nose Neoplasms / Q000532:radiotherapy; D011832:Radiation Injuries; D011867:Radioisotope Teletherapy / Q000009:adverse effects*; D012867:Skin / Q000473:pathology
chemical_list: D003037:Cobalt Radioisotopes