[Chromosomal structure or porcine lymphocytes effected by food additives].
Different concentrations of food additives were introduced in cultures of pig lymphocytes. No special chromosomal damage were induced by anticoccidians. On the contrary some antibiotics caused chromosomic anomalies. Chloramphenicol and furazolidone assayed in vitro and in vivo had also an antimitotic effect. The purpose of this work was to know the cytotoxic effect of some substances: a preliminary and cheap test could be a cytogenetic examination in vitro.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002869:Chromosome Aberrations / Q000187:drug effects; D002875:Chromosomes / Q000502:physiology*; D005503:Food Additives / Q000494:pharmacology*; D007621:Karyotyping; D008214:Lymphocytes / Q000187:drug effects / Q000502:physiology*; D013552:Swine
D000900:Anti-Bacterial Agents; D005503:Food Additives
Structure chromosomique des lymphocytes du porc et additifs alimentaires.