Effects of the third (aqueous) extract of ginseng on the cardiovascular dynamics of dogs during halothane anesthesia.
An electromagnetic flowmeter probe was chronically implanted around the ascending aorta in a group of dogs. Subsequently, ten dogs were lightly anesthetized with halothane (0.75%) and the third (aqueous) extract of ginseng (40 mg/kg) was administered intravenously. Five dogs were anesthetized without the administration of ginseng. Eleven cardiovascular variables including cardiac output, stroke volume, heart rate, mean arterial pressure, pulse pressure, central venous pressure, total peripheral resistance, pH, PaCO2, PaO2, and base deficit were compared. The cardiac output, stroke volume, and central venous pressure were decreased significantly, while total peripheral resistance was increased significantly following ginseng.
D000769:Anesthesia, Inhalation; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D004285:Dogs; D006221:Halothane; D006439:Hemodynamics / Q000187:drug effects*; D005894:Panax; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D012212:Rheology; D013318:Stroke Volume / Q000187:drug effects; D014655:Vascular Resistance / Q000187:drug effects; D014867:Water
D010936:Plant Extracts; D014867:Water; D006221:Halothane