title: Down's syndrome and maternal age in British Columbia, 1972--75.
abstract: The occurrence of Down's syndrome in British Columbia during the period 1972-75 is analyzed with respect to maternal age distribution. This period is compared with previously studied periods. No marked trends are evident in the various age group-specific rates studied. The significance of these findings is discussed in connection with a possible role of environmental nutagens in induction of Down's syndrome and the maternal age effect.
mesh_terms: D000328:Adult; D000367:Age Factors; D001955:British Columbia; D004314:Down Syndrome / Q000453:epidemiology* / Q000209:etiology; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008423:Maternal Age; D008875:Middle Aged; D009153:Mutagens; D011247:Pregnancy
chemical_list: D009153:Mutagens