[Effects of the virus-inhibiting factor or interferon on the in vitro multiplication of mouse tumor cells].
1) The in vitro effect of virus-inhibiting factor (IF) or interferon on Ehrlich ascites tumor and sarcoma 180 was found to be cytostatic, but not cytocidal. 2) Mouse peritoneal macrophages or splenic lymphoid cells, in the presence of IF, did not affect multiplication of the tumor cells examined.
D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology; D002286:Carcinoma, Ehrlich Tumor / Q000473:pathology*; D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D003513:Cycloheximide / Q000494:pharmacology; D003703:Demecolcine / Q000494:pharmacology; D066298:In Vitro Techniques; D007372:Interferons / Q000494:pharmacology*; D008214:Lymphocytes / Q000502:physiology; D008264:Macrophages / Q000502:physiology; D008297:Male; D051379:Mice; D012510:Sarcoma 180 / Q000473:pathology*
D000964:Antimetabolites, Antineoplastic; D007372:Interferons; D003513:Cycloheximide; D003703:Demecolcine
Effet du facteur inhibiteur des virus ou interféron sur la multiplication in vitro des cellules malignes murines.