title: [Juvenile hormone in diapausing Pieris brassicae and mutations. Tetrahydrofolic acid and pterins incubated in chrysalids, provoking ontogenic and mutagenic genetic information alterations in Drosophila melanogaster].
abstract: Study of AMPc phosphodiesterase shows presence of JH in diapausing chrysalids and antogonistic action of FH and pterines. Study of farnesoldeshydrogenase and farnesal deshydrogenase in Dm shows that FH4 and pterines inhibite FDH, active ADH. Conclusion is JH in diapause chrysalides is active factor with FH4 provoking genesis of pigmentary mutation, cellular proliferation or growth deficiencies. Comparison with JH+FH4+ teromes incubated in Bar (Muller 5) mutants of Dm in place of diapausing chrysalids reproduce larval deficiences, mosaics and mutations observed in precedent experiments.
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000032:analysis; D000429:Alcohol Oxidoreductases / Q000032:analysis; D000445:Aldehyde Oxidoreductases / Q000032:analysis; D000818:Animals; D002080:Butterflies / Q000187:drug effects* / Q000201:enzymology; D004247:DNA / Q000096:biosynthesis; D004331:Drosophila melanogaster / Q000187:drug effects* / Q000201:enzymology; D005204:Farnesol / Q000378:metabolism; D007605:Juvenile Hormones / Q000494:pharmacology*; D007814:Larva; D007915:Lepidoptera / Q000187:drug effects*; D002955:Leucovorin / Q000494:pharmacology; D009154:Mutation; D009758:Nymph; D011622:Pterins / Q000494:pharmacology; D012313:RNA / Q000096:biosynthesis; D013763:Tetrahydrofolates / Q000494:pharmacology
chemical_list: D007605:Juvenile Hormones; D011622:Pterins; D013763:Tetrahydrofolates; D005204:Farnesol; D012313:RNA; D004247:DNA; D000429:Alcohol Oxidoreductases; D000445:Aldehyde Oxidoreductases; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D002955:Leucovorin
vernacular_title: Hormone juvénile de Pieris brassicae diapausante et mutations. Acide tétrahydrofolique et ptérines incubés dans ces chrysalides provoquant chez Drosophila melanogaster des altérations de l'information génétique ontogènes et mutagènes