title: Synthesis and antitumor properties of 7-deoxy-7-[(cis- and trans-3-aminocyclohexane)thio]carminomycinone.
abstract: The synthesis of analogues of carminomycin in which the daunosamine group has been replaced by (cis- and trans-3-aminocyclohexane)thio moieties is described. The new compounds were found to exhibit none of the antitumor or antibiotic activity associated with carminomycin.
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D001412:Bacillus subtilis / Q000187:drug effects; D010582:Bacteriophage lambda / Q000254:growth & development; D002360:Carubicin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D003630:Daunorubicin / Q000031:analogs & derivatives*; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D013237:Stereoisomerism; D014775:Virus Activation / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents; D002360:Carubicin; D003630:Daunorubicin