[Androgen receptors in the cytosol of normal mucosa and of pharyngo-laryngeal epitheliomas in humans].
Specific binding for 5 alpha dihydrotestosterone has been characterized in cytosol fraction from human pharyngeal and laryngeal mucosae. The high binding affinity of the protein receptor (Kd 2 x 10(-10)M) and its low capacity are similar in both sexes, and similar in both normal mucosa and epithelioma.
D001665:Binding Sites; D003600:Cytosol / Q000378:metabolism; D013196:Dihydrotestosterone / Q000378:metabolism*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000378:metabolism*; D007830:Larynx / Q000378:metabolism*; D008297:Male; D009092:Mucous Membrane / Q000378:metabolism / Q000648:ultrastructure; D010610:Pharyngeal Neoplasms / Q000378:metabolism*; D010614:Pharynx / Q000378:metabolism*; D011485:Protein Binding; D011956:Receptors, Cell Surface; D012737:Sex Factors
D011956:Receptors, Cell Surface; D013196:Dihydrotestosterone
Récepteurs d'androgénes: mise en évidence dans la fraction cytosolique de muqueuse normale et d'épithéliomas pharyngo-laryngés humains