title: LEg venous oxygen saturation in the evaluation of intra-operative blood flow during arterial reconstructive surgery.
abstract: In twenty-four patients, undergoing a femoro-popliteal saphenous vein bypass graft for symptomatic atherosclerotic occlusion of the superficial femoral artery, oxygen saturation values for the femoral and popliteal veins were compared to the directly measured blood flows in the common femoral artery and in the bypass graft, respectively. Blood flow and venous oxygen saturation increased significantly after transfusion of 900 ml of blood. Pharmacological vasodilation caused a significant increase in blood flow both before and after transfusion, whereas the changes in venous oxygen saturation were significant only before blood transfusion. A close statistical relationship was found between initial femoral venous oxygen saturation and initial blood flow in the common femoral artery as well as between initial popliteal venous oxygen saturation and initial byapss blood flow. However, especially at low saturation values, the evaluation of blood flow was very uncertain. Whole leg and lower leg oxygen uptakes were not altered by intraoperative changes in blood volume. It is concluded that blood flow in the common femoral artery and the bypass graft can be roughly estimated from analysis of oxygen saturation in the femoral and popliteal veins, respectively. Furthermore, by determining leg venous oxygen saturation both before and after flow augmentation, induced by pharmacological vasodilation, a conception of the load on the vascular system may be obtained.
mesh_terms: D000368:Aged; D001157:Arterial Occlusive Diseases / Q000601:surgery; D001158:Arteries / Q000601:surgery*; D001161:Arteriosclerosis / Q000601:surgery*; D001803:Blood Transfusion; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D005268:Femoral Vein; D006801:Humans; D007383:Intermittent Claudication / Q000601:surgery*; D007432:Intraoperative Period; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*; D011150:Popliteal Artery / Q000601:surgery*; D011152:Popliteal Vein; D012039:Regional Blood Flow; D012212:Rheology; D012501:Saphenous Vein / Q000637:transplantation*; D014182:Transplantation, Autologous; D014665:Vasodilator Agents
chemical_list: D014665:Vasodilator Agents; D010100:Oxygen