Diphasic action of the aliphatic amide, HOE 17879, on hepatic microsomal drug metabolizing enzymes in the mouse.
D000577:Amides / Q000494:pharmacology*; D000818:Animals; D001713:Biphenyl Compounds / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003579:Cytochrome Reductases / Q000378:metabolism; D003574:Cytochrome c Group / Q000378:metabolism; D006140:Guaifenesin / Q000494:pharmacology; D006591:Hexobarbital / Q000494:pharmacology; D008297:Male; D051379:Mice; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009119:Muscle Contraction / Q000187:drug effects; D009246:NADH Tetrazolium Reductase / Q000378:metabolism; D009252:NADPH Dehydrogenase / Q000378:metabolism; D009575:Nitroanisole O-Demethylase / Q000378:metabolism; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism; D010090:Oxidoreductases, O-Demethylating / Q000378:metabolism; D012890:Sleep / Q000187:drug effects; D014403:Tubocurarine / Q000494:pharmacology
D000577:Amides; D001713:Biphenyl Compounds; D003574:Cytochrome c Group; D006140:Guaifenesin; C012142:HOE 17879; D003577:Cytochrome P-450 Enzyme System; D006591:Hexobarbital; D006899:Mixed Function Oxygenases; D009575:Nitroanisole O-Demethylase; D010090:Oxidoreductases, O-Demethylating; D010089:Oxidoreductases, N-Demethylating; D009246:NADH Tetrazolium Reductase; D003579:Cytochrome Reductases; D009252:NADPH Dehydrogenase; D014403:Tubocurarine