Muscle biopsy in hypotonic schizophrenic children: a preliminary report.
Two hypotonic boys, aged 7 years, 3 months and 7 yers, 7 months, who possessed sufficient speech to demonstrate a severe thought disorder and who differed markedly in their activity levels, were subjected to a biopsy of the quadriceps muscle. The biopsies revealed atrophy of type 2 muscle fibers, as well as variability in the size of these fibers. The findings could be compatible with a denervation phenomenon.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D002648:Child; D006801:Humans; D008297:Male; D009123:Muscle Hypotonia / Q000201:enzymology / Q000473:pathology*; D009132:Muscles / Q000201:enzymology / Q000473:pathology; D012561:Schizophrenia, Childhood / Q000201:enzymology / Q000473:pathology*
D000251:Adenosine Triphosphatases