Induction of SMON-type virus form avian infectious laryngotracheitis virus.
SMON-type virus which shows different host range was induced from ILT virus under unsuitable culture conditions for the growth of the parental ILT virus, such as cultivation in CAM of 12-day-old eggs or cultivation in CHK cells at 32 degrees. Furthermore, it was induced from ILT virus by mutagenesis by either BrdU or NG in CHK cell cultures.
D000367:Age Factors; D000818:Animals; D001973:Bromodeoxyuridine; D002478:Cells, Cultured; D002645:Chickens; D006224:Cricetinae; D003588:Cytopathogenic Effect, Viral; D004531:Eggs; D006564:Herpesviridae / Q000254:growth & development*; D001352:Herpesvirus 1, Gallid / Q000254:growth & development; D009154:Mutation; D009604:Nitrosoguanidines; D013045:Species Specificity; D013696:Temperature; D014776:Virus Cultivation; D014779:Virus Replication
D009604:Nitrosoguanidines; D001973:Bromodeoxyuridine