Corticoid uptake by the paraventricular nucleus in the hypothalamus of the duck, Anas platyrhynchos.
3H-corticoids were localized by autoradiography in small neurons in the area of the magnocellular paraventricular nucleus of mallard ducks. Correlative data show that: (1) the label is principally unmetabolized steroid, (2) the hypothalamus competitively binds corticosterone, (3) the paraventricular nucleus contains immunoreactive neurophysin, is richly innervated by boutons of monoaminergic nerves and is involved in the adaptive response to osmotic stress.
D000305:Adrenal Cortex Hormones / Q000378:metabolism*; D000818:Animals; D001345:Autoradiography; D001667:Binding, Competitive; D003600:Cytosol / Q000378:metabolism; D004372:Ducks / Q000378:metabolism*; D005246:Feedback; D007031:Hypothalamus / Q000378:metabolism*; D008473:Median Eminence / Q000378:metabolism; D009474:Neurons / Q000378:metabolism; D009481:Neurophysins / Q000032:analysis; D010286:Paraventricular Hypothalamic Nucleus / Q000378:metabolism*; D010913:Pituitary-Adrenal System / Q000502:physiology; D011956:Receptors, Cell Surface; D013312:Stress, Physiological; D014883:Water-Electrolyte Imbalance
D000305:Adrenal Cortex Hormones; D009481:Neurophysins; D011956:Receptors, Cell Surface