Characterization of reactive and suppressive cells in the mouse embryonic liver by peanut agglutinin (PNA).
Embryonic liver cells suppressed the MLC response of adult mouse spleen cells and reactivity to mitogens Con A, PHA and LPS. Suppression was exerted by cells agglutinated by PNA (PNA+ cells). Cells reacting to LPS and to DxS were found in the nonagglutinated (PNA-) cell fraction. The PNA+ fraction did not react to DxS nor did it reduce the response of sdult spleen cells to this mitogen.
D000818:Animals; D010367:Arachis; D001402:B-Lymphocytes / Q000276:immunology; D002469:Cell Separation; D003208:Concanavalin A / Q000494:pharmacology; D004622:Embryo, Mammalian / Q000276:immunology*; D005260:Female; D037102:Lectins / Q000494:pharmacology*; D008070:Lipopolysaccharides / Q000494:pharmacology; D008099:Liver / Q000276:immunology*; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D010835:Phytohemagglutinins / Q000494:pharmacology; D037121:Plant Lectins; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
D037102:Lectins; D008070:Lipopolysaccharides; D010835:Phytohemagglutinins; D037121:Plant Lectins; D003208:Concanavalin A