title: Hepatitis in skunks caused by the virus of infectious canine hepatitis.
abstract: Two cases of acute, fatal, hepatitis occurred in young, striped skunks (Mephitis mephitis) trapped in southern Ontario. Histologically, lesions in the liver were similar to infectious canine hepatitis. A virus was isolated which produced large intranuclear inclusions in dog kidney cell cultures. These inclusions were Feulgen-positive and fluoresced green with acridine orange stain. The skunk hepatitis isolate was identified as the virus of infectious canine hepatitis by virus neutralization tests.
mesh_terms: D006516:Adenoviruses, Canine / Q000254:growth & development / Q000276:immunology; D000818:Animals; D002335:Carnivora; D004285:Dogs; D005260:Female; D006522:Hepatitis, Infectious Canine / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D008099:Liver / Q000473:pathology; D008297:Male; D012889:Mephitidae