title: Role of ionophores in energy coupling.
abstract: If, as we deem inevitable, the principles of energy coupling are universal, then the necessity for charge-separating devices will apply across the board to all bioenergetic systems. Since, apart from the elctron transfer chain, ionophores are the only charge-separating devices available in bioenergetic systems, model of energy coupling that does not feature this central role of ionophores can be taken seriously. The ionophore approach thus opens the royal highway to the ultimate solution of all bioenergetic problems.
mesh_terms: D000255:Adenosine Triphosphate / Q000096:biosynthesis; D001693:Biological Transport, Active; D002352:Carrier Proteins / Q000378:metabolism; D003574:Cytochrome c Group / Q000378:metabolism; D004579:Electron Transport; D004734:Energy Metabolism; D006728:Hormones; D007476:Ionophores / Q000378:metabolism; D008567:Membranes, Artificial; D008928:Mitochondria / Q000378:metabolism; D008954:Models, Biological; D010085:Oxidative Phosphorylation; D010713:Phosphatidylcholines; D010743:Phospholipids / Q000378:metabolism; D013228:Stearates / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D002352:Carrier Proteins; D003574:Cytochrome c Group; D006728:Hormones; D007476:Ionophores; D008567:Membranes, Artificial; D010713:Phosphatidylcholines; D010743:Phospholipids; D013228:Stearates; D000255:Adenosine Triphosphate