title: Effects of hypophysectomy, bilateral adrenalectomy and hormone replacement therapy upon organ monoamine oxidase activity.
abstract: Changes in MAO activity after hypophysectomy (HX) are not due to adrenal insufficiency. ACTH failed to reverse the effects of HX and enhanced the depression of cardiac and spleenic MAO. The data suggests both facilitatory and inhibitory effects of pituitary hormones on MAO activity.
mesh_terms: D000311:Adrenal Glands / Q000201:enzymology / Q000502:physiology*; D000313:Adrenal Medulla / Q000502:physiology; D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000818:Animals; D001921:Brain / Q000201:enzymology; D003907:Dexamethasone / Q000494:pharmacology; D005725:Ganglia, Autonomic / Q000201:enzymology; D007016:Hypophysectomy; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008297:Male; D008995:Monoamine Oxidase / Q000378:metabolism*; D009206:Myocardium / Q000201:enzymology; D010902:Pituitary Gland / Q000502:physiology*; D051381:Rats; D013154:Spleen / Q000201:enzymology; D014649:Vas Deferens / Q000201:enzymology
chemical_list: D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone; D008995:Monoamine Oxidase