Isolation of low-virulent mouse hepatitis virus from nude mice with wasting syndrome and hepatitis.
Mouse hepatitis viruses were isolated on DBT cell culture from affected livers in most nude mice having wasting syndrome and chronic hepatitis. These nude isolates were pathogenic for cortisone-treated ICR weanling mice but not for non-treated ones.
D000818:Animals; D000956:Antigens, Viral; D001491:Basophils / Q000648:ultrastructure; D006520:Hepatitis, Animal / Q000276:immunology / Q000382:microbiology* / Q000473:pathology; D008099:Liver / Q000473:pathology; D051379:Mice; D008819:Mice, Nude / Q000382:microbiology*; D006517:Murine hepatitis virus / Q000276:immunology / Q000302:isolation & purification* / Q000472:pathogenicity
D000956:Antigens, Viral