Detection of a virus-specific antigen on the surface of herpes simplex virus-transformed cells.
A virion-associated antigen, CP-1, was detected on the surface of hamster cells after transformation by inactivated herpes simplex virus type 1. Presence of the CP-1 antigen on the cells correlates with the synthesis of antibody by tumorbearing hamsters capable of neutralizing both herpes simplex virus types 1 and 2.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology*; D002471:Cell Transformation, Neoplastic; D006224:Cricetinae; D004622:Embryo, Mammalian; D005347:Fibroblasts; D005455:Fluorescent Antibody Technique; D018139:Simplexvirus / Q000254:growth & development* / Q000276:immunology
D000956:Antigens, Viral