title: Addition of fluoride to pit and fissure sealants--a feasibility study.
abstract: The data obtained in this in vitro study indicate that contact with pit and fissure sealants to which NaF has been added in amounts ranging from 2 to 5% substantially increases the fluoride content of the enamel and reduces its solubility in acid. The properties of the materials do not seem to be impaired by the addition of fluoride in these amounts. It thus appears that this approach to providing a backup anticariogenic mechanism may, indeed, be feasible. However, further investigation must be done to confirm the anticariogenic effect and to establish the most efficacious means of fluoride incorporation in the materials.
mesh_terms: D000180:Acrylic Resins; D000327:Adsorption; D001840:Dental Bonding; D003743:Dental Enamel / Q000378:metabolism; D003747:Dental Enamel Solubility / Q000187:drug effects; D003764:Dental Materials; D005460:Fluorides, Topical / Q000378:metabolism / Q000494:pharmacology; D006244:Hardness; D010895:Pit and Fissure Sealants; D012822:Silicon Dioxide; D012964:Sodium; D013314:Stress, Mechanical; D013499:Surface Properties; D014099:Toothbrushing; D014867:Water
chemical_list: D000180:Acrylic Resins; D003764:Dental Materials; D005460:Fluorides, Topical; D010895:Pit and Fissure Sealants; D014867:Water; D012822:Silicon Dioxide; D012964:Sodium