[Stimulation by ACTH of protein synthesis in cultured adrenal cells. Absence of an effect by cyclin AMP].
ACTH stimulates the incorporation of 14C-leucine into proteins of adrenal tumor cells in culture. This stimulation though about 20% over controls is statistically significant. Cyclic AMP did not reproduce the stimulation observed with ACTH.
D000311:Adrenal Glands / Q000187:drug effects* / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D002478:Cells, Cultured; D000242:Cyclic AMP / Q000494:pharmacology*; D003513:Cycloheximide / Q000494:pharmacology; D051379:Mice; D014176:Protein Biosynthesis
D000324:Adrenocorticotropic Hormone; D003513:Cycloheximide; D000242:Cyclic AMP
Stimulation par l'ACTH de la synthèse protéique de cellules surrénaliennes en culture. Absence d'effet de l'AMP cyclique