Mapping AK1, ACONs, and AK3 to chromosome 9 in man employing and X/9 translocation and somatic cell hybrids.
The adenylate kinase 1 (AK1), adenylate kinase3 (AK3), and aconitaseS (ACONS) genes have been assigned to chromosome 9 in man by employing an X/9 translocation segregating in man-mouse somatic cell hybrids. Segregation was controlled by taking advantage of the HAT/8-azaguanine selection-counterselection strategy directed at the X-linked HPRT locus. Assignment of AK1 to chromosome 9 has suggested the assignment of the ABO blood-group locus and the nail-patella (Np) locus to 9, since both loci are linked to AK1 by family studies.
D000154:Aconitate Hydratase; D000263:Adenylate Kinase; D000818:Animals; D002869:Chromosome Aberrations; D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000201:enzymology; D006836:Hydro-Lyases; D051379:Mice; D010770:Phosphotransferases; D012730:Sex Chromosomes; D014178:Translocation, Genetic
D010770:Phosphotransferases; D000263:Adenylate Kinase; D006836:Hydro-Lyases; D000154:Aconitate Hydratase