A transitional cell carcinoma cell line.
A transitional cell carcinoma cell line, COLO 232, was derived from a primary urinary bladder tumor in a Caucasian male. In culture, COLO 232 retained distinct uroepithelial phenotypic traits and produced both carcinoembryonic antigen and adrenocorticotropic hormone. COLO 232 had a chromosome mode of 58 and retained the X and Y chromosomes. Ten marker chromosomes were identified. COLO 232 will be of value for biochemical and immunological studies.
D000324:Adrenocorticotropic Hormone / Q000096:biosynthesis; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002295:Carcinoma, Transitional Cell; D002460:Cell Line; D002877:Chromosomes, Human / Q000032:analysis; D006801:Humans; D008297:Male; D001749:Urinary Bladder Neoplasms
D002272:Carcinoembryonic Antigen; D000324:Adrenocorticotropic Hormone