[Effects of aflatoxins B1 on glucose-6-phosphatase activity in kidney and liver of rats (Rattus rattus norvegicus)].
The authors observed the influence of the B1 aflatoxin over rat liver and kidneys glucose-6-phosphatase activity. Animals aged 30 and 60 days received B1 aflatoxin in oil, 1 mcg/g and 5 mcg/g of body weight. The parameters were observed 6, 24 and 48 hours after the micotoxin administration. There was significant decrease of glucemia in the 30 days animals. In the 60 days animals the results suggested possible increase in the liver glucose-6-phosphatase and marked decrease in glycogen.
D000348:Aflatoxins / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001798:Blood Proteins; D005952:Glucose-6-Phosphatase / Q000378:metabolism*; D006003:Glycogen / Q000097:blood; D007668:Kidney / Q000201:enzymology*; D008099:Liver / Q000201:enzymology*; D008297:Male; D051381:Rats
D000348:Aflatoxins; D001786:Blood Glucose; D001798:Blood Proteins; D006003:Glycogen; D005952:Glucose-6-Phosphatase
Influência da aflatoxina B1 sobre a atividade da glicose-6-fosfatase de fígado e rim de ratos (Rattus rattus norvegicus).