Hepatitis B virus, cirrhosis and primary carcinoma of the liver. An electron microscopic study.
The core and coat of hepatitis B virus were found by electron microscopy in parenchymal cells of a liver biopsy from a 61 year old man with chronic active hepatitis and cirrhosis of the liver. Laparoscopy, 35 days after liver biopsy, and autopsy 42 days later confirmed the cirrhosis and showed in addition a well differentiated hepatoma. The possibility of a viral aetiology for the cirrhosis and primary carcinoma of the liver is considered.
D006528:Carcinoma, Hepatocellular / Q000382:microbiology*; D006515:Hepatitis B virus / Q000032:analysis*; D006801:Humans; D008099:Liver / Q000382:microbiology; D008103:Liver Cirrhosis / Q000382:microbiology*; D008113:Liver Neoplasms / Q000382:microbiology*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged