Response of neonatal mouse lung in organ culture to silica.
Short term organ cultures of lung fragments from neonatal mice maintain their normal architecture. Cultures exposed to silica flour in varying concentrations show effects resembling those seen in chronic silicosis produced by inoculation and inhalation methods.
D008168:Lung / Q000187:drug effects*; D008264:Macrophages / Q000473:pathology; D009924:Organ Culture Techniques; D012822:Silicon Dioxide / Q000494:pharmacology*; D012829:Silicosis / Q000473:pathology*
D012822:Silicon Dioxide