title: Developmentally regulated cyclic AMP-dependent protein kinases in Dictyostelium discoideum.
abstract: Two apparently distinct species of cyclic AMP-dependent protein kinase appear during the first 1-2 hr of development in Dictyostelium discoideum; no such activity can be detected in vegetative cell extracts. These two kinases are similar in properties to the type I and II cyclic AMP-dependent protein kinases found in a number of mammalian tissues. Their time of appearance supports the idea that one or both mediate the effects of cyclic AMP on gene expression early in Dictyostelium development.
mesh_terms: D002457:Cell Extracts / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism; D004023:Dictyostelium / Q000201:enzymology* / Q000254:growth & development; D007527:Isoenzymes / Q000096:biosynthesis* / Q000378:metabolism; D009235:Myxomycetes / Q000201:enzymology*; D011494:Protein Kinases / Q000096:biosynthesis* / Q000378:metabolism
chemical_list: D002457:Cell Extracts; D007527:Isoenzymes; D000242:Cyclic AMP; D011494:Protein Kinases