title: Ovarian tumors and related lesions in aged chimpanzees.
abstract: The ovaries of a 48-year-old chimpanzee each contained a large bilateral fibrothecoma. A 39-year-old chimpanzee had two small fibrothecomas in one ovary and a well-differentiated Sertoli-Leydig cell tumor in the other; there also was adenomatous hyperplasia of the endometrium. Both animals had extensive thecal hypertrophy in the ovaries. Thecal hypertrophy might have been a source of excessive estrogen and could have been a partial cause of the ovarian tumors.
mesh_terms: D000818:Animals; D005260:Female; D007984:Leydig Cell Tumor / Q000473:pathology / Q000662:veterinary*; D010051:Ovarian Neoplasms / Q000473:pathology / Q000662:veterinary*; D010053:Ovary / Q000473:pathology; D002679:Pan troglodytes; D012707:Sertoli Cell Tumor / Q000473:pathology / Q000662:veterinary*; D013798:Thecoma / Q000473:pathology / Q000662:veterinary*; D014599:Uterus / Q000473:pathology