Deactivation of persistently activated pancreatic adenylate cyclase. Evidence of uncoupling of hormone receptors and enzyme effector in the persistently activated state, and of the presence of two guanyl nucleotide regulatory sites.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D002462:Cell Membrane / Q000201:enzymology; D002766:Cholecystokinin / Q000494:pharmacology; D004789:Enzyme Activation / Q000187:drug effects; D006150:Guanine Nucleotides / Q000378:metabolism*; D006165:Guanylyl Imidodiphosphate / Q000494:pharmacology; D007700:Kinetics; D010179:Pancreas / Q000201:enzymology*; D051381:Rats; D011956:Receptors, Cell Surface / Q000378:metabolism; D012633:Secretin / Q000494:pharmacology
D006150:Guanine Nucleotides; D011956:Receptors, Cell Surface; D012633:Secretin; D006165:Guanylyl Imidodiphosphate; D002766:Cholecystokinin; D000262:Adenylyl Cyclases