Glycolipids in model membranes. Spin label and freeze-etch studies.
1. Several types of glycolipid are examined in lipid bilayer model membranes as part of a program to clarify their fuction in living cells. 2. Data obtained with three spin labelled derivatives of galactosyl ceramide is reported showing a fatty acid fluidity gradient similar to that obtained with phospholipid spin labels. Some possible structural implications of the observed differences are considered. 3. Results obtained using Freeze-Etch electron microscopy and hemagglutination inhibition are given showing beef brain gangliosides in lipid vesicles to be effective receptors for influenza virus.
D002518:Ceramides; D004578:Electron Spin Resonance Spectroscopy; D005613:Freeze Etching; D008081:Liposomes; D008563:Membrane Lipids; D008854:Microscopy, Electron; D008954:Models, Biological; D008968:Molecular Conformation; D009975:Orthomyxoviridae / Q000648:ultrastructure; D010713:Phosphatidylcholines; D013113:Spin Labels
D002518:Ceramides; D008081:Liposomes; D008563:Membrane Lipids; D010713:Phosphatidylcholines; D013113:Spin Labels