Administration of antigen by intralymphatic route in the rat. II. Results in tumor active immunotherapy (delta). Preliminary report.
Tumor growth and survival time were followed in rats transplanted with Morris hepatoma 5123 and previously injected with a crude homogenate of the same tumor by the intradermic or intralymphatic route. Female rats treated by the intralymphatic route showed a longer survival time and impaired tumor growth. Male rats did not show any difference.
D000818:Animals; D000917:Antibody Formation; D000951:Antigens, Neoplasm / Q000008:administration & dosage*; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D005260:Female; D007167:Immunotherapy / Q000379:methods*; D007272:Injections, Intralymphatic; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental; D051381:Rats; D011919:Rats, Inbred Strains; D014184:Transplantation, Homologous
D000951:Antigens, Neoplasm