title: [Molecular aspects of the action of insulin].
abstract: Molecular aspects of the insulin action in an organism are discussed. The following mechanisms of the hormone effect are considered: induction of the synthesis of glycolytic enzymes in cell-targets under effect of insulin; mechanisms of the insulin reception in cell-enzymes in cell-targets; the possible role of cyclic nucleotides as mediators in the effect of insulin in cell targets.
mesh_terms: D000273:Adipose Tissue / Q000166:cytology; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D002463:Cell Membrane Permeability; D000242:Cyclic AMP / Q000378:metabolism; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D005943:Gluconeogenesis; D005947:Glucose / Q000378:metabolism; D005952:Glucose-6-Phosphatase / Q000037:antagonists & inhibitors; D006003:Glycogen / Q000096:biosynthesis; D006019:Glycolysis; D006593:Hexokinase / Q000378:metabolism; D007328:Insulin / Q000502:physiology*; D007527:Isoenzymes / Q000378:metabolism; D008099:Liver / Q000166:cytology; D009132:Muscles / Q000166:cytology; D010085:Oxidative Phosphorylation; D010729:Phosphoenolpyruvate Carboxykinase (GTP) / Q000037:antagonists & inhibitors; D010744:Phosphoric Monoester Hydrolases / Q000037:antagonists & inhibitors; D011766:Pyruvate Carboxylase / Q000037:antagonists & inhibitors; D011770:Pyruvate Kinase / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D014158:Transcription, Genetic
chemical_list: D007328:Insulin; D007527:Isoenzymes; D006003:Glycogen; D000242:Cyclic AMP; D006593:Hexokinase; D011770:Pyruvate Kinase; D012321:DNA-Directed RNA Polymerases; D010744:Phosphoric Monoester Hydrolases; D005952:Glucose-6-Phosphatase; D010729:Phosphoenolpyruvate Carboxykinase (GTP); D011766:Pyruvate Carboxylase; D005947:Glucose
vernacular_title: Molekuliarnye aspekty deĭstviia insulina