Intraventricular Met5-enkephalin causes unexpected lowering of pain threshold and narcotic withdrawal signs in rats.
D000818:Animals; D006801:Humans; D007276:Injections, Intraventricular; D007930:Leucine; D008297:Male; D008715:Methionine; D009020:Morphine / Q000494:pharmacology; D009419:Nerve Tissue Proteins / Q000494:pharmacology*; D009842:Oligopeptides / Q000494:pharmacology*; D010146:Pain / Q000503:physiopathology*; D051381:Rats; D011957:Receptors, Opioid / Q000502:physiology; D013329:Structure-Activity Relationship; D013375:Substance Withdrawal Syndrome / Q000139:chemically induced*
D009419:Nerve Tissue Proteins; D009842:Oligopeptides; D011957:Receptors, Opioid; D009020:Morphine; D008715:Methionine; D007930:Leucine