title: Interaction of histones with human serum proteins.
abstract: The authors describe the interactions of whole calf thymus histone and its fractions with the human serum proteins. Immunoelectrophoretic analysis revealed two types of interactions: 1) a decrease in the electrophoretic mobility of a whole, immunochemically uniform fraction, and 2) a decrease in the electrophoretic mobility of only some molecules of such a fraction. In this association, the arginine-rich histone fraction (F3) was found to be the most active. The findings are important for interpreting the results of biological treatments.
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000378:metabolism*; D002417:Cattle; D006657:Histones / Q000097:blood*; D007136:Immunoglobulins / Q000302:isolation & purification; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008259:Macroglobulins / Q000378:metabolism; D013950:Thymus Gland / Q000378:metabolism
chemical_list: D001798:Blood Proteins; D006657:Histones; D007136:Immunoglobulins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008259:Macroglobulins