[Antigenic activity of Bordetella pertussis during cultivation in liquid nutrient media].
The authors studied the antigenic activity of Bordetella pertussis during stab cultivation. For the first time there were revealed changes (oscillations) of antigenic activity: formation of 3 peaks of which the middle was the highest. A possibility of improving the quality of pertussis vaccine by using biomass at the height of the peak was experimentally founded.
D000942:Antigens, Bacterial / Q000032:analysis; D001886:Bordetella pertussis / Q000254:growth & development / Q000276:immunology*; D003470:Culture Media; D006386:Hemagglutination Tests; D010567:Pertussis Vaccine
D000942:Antigens, Bacterial; D003470:Culture Media; D010567:Pertussis Vaccine
Antigennaia aktivnost' kokliushnykh bakteriĭ v protsesse kul'tivirovaniia v zhidkoĭ pitatel'noi srede.