[Preliminary observations on the results of treating malignant lymphoma with Lycurim].
The authors gave Lycurim to 30 patients with malignant lymphoma (LLC--12 cases, Hodgkin's disease - 15 cases, reticulosarcoma - 2 cases and lymphosarcoma - 1 case). The patients were divided into three groups. Group I received only Lycurim, group II - Lycurim and prednisone, group III - Lycurim and Solcoseryl. Significant improvement was observed in 22 patients, with complete remission in 5 cases and partial in 17 cases. Leucopenia and thrombocytopenia precluding treatment were never observed in cases treated simultaneously with prednisone or Solcoseryl. The authors believe that the proportion of remissions may be increased combining Lycurim with vincristine, procarbazine and glycocorticosteroids (LOP or LOPP).
D000183:Actihaemyl / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000477:Alkylating Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004896:Erythritol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006689:Hodgkin Disease / Q000188:drug therapy; D006801:Humans; D007275:Injections, Intravenous; D008223:Lymphoma / Q000188:drug therapy*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000188:drug therapy; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy; D008698:Mesylates / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D012075:Remission, Spontaneous
D000477:Alkylating Agents; D008698:Mesylates; D000183:Actihaemyl; D004896:Erythritol; D011241:Prednisone
Wstepne obserwacje dotyczace wyników leczenia chłoniaków złośliwych preparatem lycurim.