title: Androgen binding in human testis.
abstract: Cytosol preparations of human testis contain macromolecules that bind tritiated dihydrotestosterone. Studies of steroid competition, heat sensitivity and dissociation rate constants indicate a similarity to serum testosterone-estradiol-binding globulin. The amount of binding of tritiated dihydrotestosterone is greater than could be explained by contamination of testis by serum.
mesh_terms: D002731:4-Chloromercuribenzenesulfonate / Q000494:pharmacology; D000368:Aged; D000728:Androgens / Q000378:metabolism*; D003534:Cyproterone / Q000494:pharmacology; D003593:Cytoplasm / Q000378:metabolism; D003600:Cytosol / Q000378:metabolism; D004054:Diethylstilbestrol / Q000494:pharmacology; D013196:Dihydrotestosterone / Q000378:metabolism; D004229:Dithiothreitol / Q000494:pharmacology; D006801:Humans; D046911:Macromolecular Substances; D008297:Male; D008875:Middle Aged; D010447:Peptide Hydrolases / Q000494:pharmacology; D011944:Receptors, Androgen / Q000378:metabolism; D013439:Sulfhydryl Reagents / Q000494:pharmacology; D013737:Testis / Q000378:metabolism* / Q000648:ultrastructure
chemical_list: D000728:Androgens; D046911:Macromolecular Substances; D011944:Receptors, Androgen; D013439:Sulfhydryl Reagents; D013196:Dihydrotestosterone; D002731:4-Chloromercuribenzenesulfonate; D004054:Diethylstilbestrol; D003534:Cyproterone; D010447:Peptide Hydrolases; D004229:Dithiothreitol