[Development and study of an experimental herpesvirus vaccine].
The strains suitable for the development of herpesvirus vaccine were selected as a result of studies on numerous herpes virus strains isolated from patients with relapsing herpes infection of various localizations. Infectious tissue culture antigens were obtained by roller cultivation of chick embryo fibroblast cultures infected with herpesvirus in the presence of 0.2% human serum albumin. A high immunogenic and antigenic activity of the experimental vaccines prepared from these antigens was established. Animal experiments demonstrated the possibility of control of the specific activity of herpesvirus vaccines.
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D000956:Antigens, Viral; D002460:Cell Line; D005557:Formaldehyde; D007114:Immunization; D007120:Immunochemistry; D051381:Rats; D018139:Simplexvirus / Q000276:immunology*; D014613:Vaccines, Attenuated; D014765:Viral Vaccines
D000914:Antibodies, Viral; D000956:Antigens, Viral; D014613:Vaccines, Attenuated; D014765:Viral Vaccines; D005557:Formaldehyde
Razrabotka i izuchenie éksperimental'noĭ protivogerpeticheskoĭ vaktsiny