title: Studies on the etiology of lymphomas in turkeys: isolation of reticuloendotheliosis in virus.
abstract: Studies of tissues from 25 normal turkey flocks and of 15 selected turkey lymphoid tumors revealed no Marek's disease or lymphoid leukosis viruses, although reticuloendotheliosis viruses (REV) were isolated from 3 flocks (2 with a history of neoplastic disease). The REV isolates were culturally and antigenically similar to the prototype REV strain T but were of low pathogenicity. Attempts failed to transmit 6 lymphoid tumors of diverse origin by inoculation into 2 strains of recipient turkeys. These data support an etiological role for REV in some though not all forms of turkey neoplastic disease.
mesh_terms: D000818:Animals; D008223:Lymphoma / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*; D011201:Poultry Diseases / Q000382:microbiology* / Q000635:transmission; D001356:Reticuloendotheliosis virus / Q000276:immunology / Q000302:isolation & purification* / Q000472:pathogenicity; D012190:Retroviridae / Q000302:isolation & purification*; D013154:Spleen / Q000382:microbiology; D014422:Turkeys