Calcium uptake by myometrial membranes: effect of A 23187, a calcium ionophore.
A subcellular fraction, relatively enriched with plasma membranes, showed an ATP-dependent Ca2+ uptake. The addition of a Ca2+. Other drugs (angiotensin, prostaglandin F2alpha, 5-hydroxytryptamine and cyclic nucleotides) had negligible effects on Ca2+ transport. The preparation appears to transport Ca2+, although binding is negligible.
D000255:Adenosine Triphosphate / Q000502:physiology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003994:Bucladesine / Q000494:pharmacology; D000001:Calcimycin / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism*; D000242:Cyclic AMP / Q000494:pharmacology; D005260:Female; D066298:In Vitro Techniques; D008566:Membranes / Q000378:metabolism; D009215:Myometrium / Q000378:metabolism*; D011460:Prostaglandins F / Q000494:pharmacology; D051381:Rats; D012701:Serotonin / Q000494:pharmacology; D013997:Time Factors; D014599:Uterus / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D011460:Prostaglandins F; D012701:Serotonin; D000001:Calcimycin; D003994:Bucladesine; D000255:Adenosine Triphosphate; D000242:Cyclic AMP; D002118:Calcium