Effect of dibutyryl cAMP and theophylline on cultured rat embryonic shields.
Effects of N6, O2 dibutyryl adenosine 3',5'-cyclic monophosphate (db-cAMP) and theophylline (Th) on cultured rat embryonic shields were studied. After addition of db-cAMP to the culture medium, an increase of the weight of explants and of the incidence of the skeletal muscle was observed. Theophylline seems to be ineffective.
D000818:Animals; D003994:Bucladesine / Q000494:pharmacology*; D046508:Culture Techniques; D004622:Embryo, Mammalian / Q000187:drug effects*; D005260:Female; D051381:Rats; D011919:Rats, Inbred Strains; D013806:Theophylline / Q000494:pharmacology*
D003994:Bucladesine; D013806:Theophylline