[Enhancement of compensatory renal hypertrophy by beta-1-24 corticotropin in the rat].
In the rat, the administration of beta1-24-corticotrophin during 7 days following an uninephrectomy enhances significantly the compensatory hypertrophy of the remaining kidney. There is no increase in renal compensatory hypertrophy when ACTH is injected to previously adrenalectomized rats. This action of ACTH could be related to the diabetes mellitus induced by this hormone or to an increase in sodium reabsorption by the tubular epithelial cells.
D000311:Adrenal Glands / Q000601:surgery; D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives*; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003366:Cosyntropin / Q000494:pharmacology*; D003404:Creatinine / Q000097:blood; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D006801:Humans; D006984:Hypertrophy; D007328:Insulin / Q000097:blood; D007668:Kidney / Q000187:drug effects / Q000473:pathology*; D009392:Nephrectomy; D009929:Organ Size; D011188:Potassium / Q000097:blood; D051381:Rats; D012964:Sodium / Q000097:blood; D014508:Urea / Q000097:blood
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D003366:Cosyntropin; D014508:Urea; D000324:Adrenocorticotropic Hormone; D012964:Sodium; D003404:Creatinine; D011188:Potassium
Stimulation de l'hypertrophie rénale compensatrice par la beta1-24 corticotrophine chez le rat.