title: Nephroblastoma in the Black child: a review of treatment in the Johannesburg Paediatric Tumour Clinic.
abstract: Twenty-five Black children with nephroblastoma who were referred to the Paediatric Tumour Clinic during the preceding 4 years, are reviewed. Results indicate that in the case of a locally advanced, fixed, primary tumour, initial surgery, even if it is combined with chemotherapy, may be a factor in the rapid postoperative development of multiple pulmonary metastases. Pre-operative irradiation appeared to be advantageous for these patients. Long-term chemotherapy holds no advantage over short-term chemotherapy.
mesh_terms: D001741:Black or African American; D000970:Antineoplastic Agents / Q000627:therapeutic use; D044383:Black People; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000628:therapy*; D008297:Male; D013019:South Africa; D009396:Wilms Tumor / Q000188:drug therapy / Q000401:mortality / Q000628:therapy*
chemical_list: D000970:Antineoplastic Agents