[Suppression of paradoxal sleep by clonidine in man].
The administration of clonidine (300 mug) suppresses REM sleep or strikingly diminishes its duration in Man. The statistical difference with placebo given in a double blind trial is highly significant. This suppression of REM sleep may depend on the stimulation of alpha-adrenergic receptors.
D000328:Adult; D002395:Catecholamines / Q000502:physiology; D003000:Clonidine / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D011941:Receptors, Adrenergic / Q000187:drug effects; D012895:Sleep, REM / Q000187:drug effects*
D002395:Catecholamines; D011941:Receptors, Adrenergic; D003000:Clonidine
Suppression du sommeil paradoxal par la clonidine chez l'Homme