Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster.
A new temperature-sensitive paralytic mutant of Drosophila, comatose, is compared behaviorally and physiologically with the previously known types, para and shi. All three have different properties with respect to kinetics of paralysis at high temperature and recovery from paralysis; com is hypersensitive to paralysis by cooling. Neurophysiological experimeents indicate different mechanisms for paralysis in each of the mutants.
D000818:Animals; D004331:Drosophila melanogaster / Q000502:physiology*; D004558:Electric Stimulation; D007700:Kinetics; D007814:Larva; D008564:Membrane Potentials; D009132:Muscles / Q000502:physiology; D009154:Mutation; D009469:Neuromuscular Junction / Q000503:physiopathology; D010243:Paralysis / Q000235:genetics* / Q000503:physiopathology; D009435:Synaptic Transmission; D013696:Temperature