[Pharmacological analysis of monoaminergic effects of the amygdaloid complex on the food-procuring conditioned reaction of rats].
The produced by microinjections of dopamine, norepinephrine, serotonin and glutamic acid into the dorsomedial divisions of the tonsil on the food-procuring conditioned reaction of rats was studied. All of the studied substances were found to lengthen the latent time of the conditioned food reaction, the number of food-procuring movements and the scope of the reflex increasing under the effect of dopamine and serotonin, but diminishing following introduction of norepinephrine and glutamic acid. The dopamine effects materialize through the medium of the tonsil neuron receptors, which are sensitive of haloperidol or chloropromazine, and those serotnin--through D-serotonin-sensitive neuron system structures of the amygdaloid complex. The inhibitory effects of norepinephrine are not of an elective nature, for they correlate with the depression of the spontaneous motor activity of the rats. The modulating influence of glutamic acid on the food-procuring conditioned reflex reaction of the rats is not associated with the action on the dopamine, or serotonin-reactive neuron systems of the dorso-medial tonsil.
D000679:Amygdala / Q000187:drug effects*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D002746:Chlorpromazine / Q000494:pharmacology; D003214:Conditioning, Classical / Q000187:drug effects*; D004087:Dihydroergotamine / Q000494:pharmacology; D004298:Dopamine / Q000494:pharmacology; D005502:Food; D005971:Glutamates / Q000494:pharmacology; D006220:Haloperidol / Q000494:pharmacology; D008297:Male; D008784:Methysergide / Q000494:pharmacology; D009020:Morphine / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology; D051381:Rats; D017981:Receptors, Neurotransmitter / Q000187:drug effects*; D012701:Serotonin / Q000494:pharmacology
D005971:Glutamates; D017981:Receptors, Neurotransmitter; D012701:Serotonin; D004087:Dihydroergotamine; D009020:Morphine; D006220:Haloperidol; D002746:Chlorpromazine; D004298:Dopamine; D009638:Norepinephrine; D008784:Methysergide
Farmakologicheskiĭ analiz monoaminergicheskikh vliianiĭ mindalevidnogo kompleksa na pishchedobyvatel'nuiu uslovnuiu reaktsiiu krys.