Morphologic aspects of nuclear bodies in a case of bronchiolar-alveolar carcinoma of the lung.
The ultrastructural features of a bronchiolar-alveolar carcinoma of the lung are described wherein the presence of nuclear bodies in many of the tumor cells were noted. Although these bodies are not viral elements, it is surmised that they may be virus associated and consequently possibly related to the etiology of this tumor. A review of the ultrastructural findings in the pulmonary adenomatosis of sheep is presented, and these are compared with those in human disease. Experimental evidence of an infectious agent responsible for human lung carcinomas is discussed, and possible avenues for future investigation are delineated.
D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged