Bovine lymphosarcoma: development of a radioimmunologic technique for detection of the etiologic agent.
A highly sensitive and specific radioimmunoassay has been developed for the major structural protein of an oncornavirus etiologically associated with bovine lymphosarcoma. This test can be used to identify cattle which have been exposed to the bovine leukemia virus and may thus develop or transmit the disease. Analysis of randomly obtained serums indicates that infection that infection with this virus is widespread among cattle.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology*; D001909:Leukemia Virus, Bovine / Q000276:immunology / Q000302:isolation & purification*; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000276:immunology / Q000662:veterinary*; D011863:Radioimmunoassay / Q000379:methods*; D012190:Retroviridae / Q000302:isolation & purification*; D014764:Viral Proteins / Q000276:immunology
D000914:Antibodies, Viral; D014764:Viral Proteins