title: Dispersion of cisternae of rough endoplasmic reticulum in aging CNS neurons: a strictly linear trend.
abstract: Dispersion of cisternae of rough endoplasmic reticulum (RER) in aging rats has been determined quantitatively for mitral cells of the olfactory bulb and Purkinje cells of the cerebellum using a recently published morphometric technique (Cruz Orive, '76). In both cell types dispersion of cisternae occurred throughout the period studied and in a linear fashion. The observed RER dispersion cannot be attributed to a decrease in the total amount of RER, since the total amount of RER was constant in Purkinje cells and increased in mitral cells during the age studied.
mesh_terms: D000375:Aging; D000818:Animals; D002531:Cerebellum / Q000166:cytology*; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D002479:Inclusion Bodies / Q000648:ultrastructure; D008297:Male; D009474:Neurons / Q000648:ultrastructure*; D009830:Olfactory Bulb / Q000166:cytology*; D011689:Purkinje Cells / Q000648:ultrastructure; D051381:Rats