Lipoprotein cholesterol in the serum of children, as determined independently by two different methods.
We separately evaluated split specimens of serum for lipoprotein cholesterol in 38 five- to 14-year-old children, by the heparin/Ca2+ precipitation method and the ultracentrifugation/dextran sulfate precipitation method. Statistical analysis of the results indicated an excellent agreement (especially in beta- and alpha-lipoprotein cholesterol values) between results by the two methods. The percentage of alpha-lipoprotein cholesterol (mean +/- SD: 38.6 +/- 5.0) in children further confirmed the earlier observations that cholesterol derived from alpha-lipoprotein in children constitutes a relatively greater part of the serum total cholesterol than is true of adults.
D000293:Adolescent; D002118:Calcium; D011232:Chemical Precipitation; D002648:Child; D002675:Child, Preschool; D002784:Cholesterol / Q000097:blood*; D003911:Dextrans; D005260:Female; D006493:Heparin; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D014461:Ultracentrifugation
D003911:Dextrans; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D006493:Heparin; D002784:Cholesterol; D002118:Calcium