The effect of ascorbic acid on infection chick-embryo ciliated tracheal organ cultures by coronavirus.
Chick embryo tracheal organ cultures showed increased resistance to infection by a coronavirus after exposure to ascorbate, while chick respiratory epithelium and allantois-on-shell preparations showed no increase in resistance to infection by an influenza virus or a paramyxovirus.
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology*; D002642:Chick Embryo; D003332:Coronaviridae / Q000254:growth & development*; D001351:Infectious bronchitis virus / Q000254:growth & development*; D009980:Influenza A virus / Q000254:growth & development; D007372:Interferons / Q000494:pharmacology; D009522:Newcastle disease virus / Q000254:growth & development; D009924:Organ Culture Techniques; D014132:Trachea; D014779:Virus Replication / Q000187:drug effects
D007372:Interferons; D001205:Ascorbic Acid