[Mechanism of calcium ion transport in brain microsome fractions].
The influence of Ca2+ in rising concentrations on the ATP-dependent Ca2+-binding system of the brain microsome fraction, the inhibitory effect of SH-reagents on it and the protective effect of ATP correlate with the properties of the Mg2+-dependent Ca2+-activated ATPase of this fraction. Such properties of the system as inactivation with an increase in Ca2+-concentration effect of phosphate and oxalate, relation to detergents cannot be explained from the view point of the tri-phosphoinozitid-dependent binding of Ca2+. These data indicate that the general mechanism of Ca2+ transport in the brain microsome fraction is similar to the mechanism of this process in the sarcoplasmatic reticulum and is realized with participation of Mg2+, Ca2+-ATPase.
D000251:Adenosine Triphosphatases / Q000502:physiology*; D000818:Animals; D001693:Biological Transport, Active; D001921:Brain / Q000378:metabolism* / Q000648:ultrastructure; D002118:Calcium / Q000378:metabolism*; D003902:Detergents / Q000494:pharmacology; D005033:Ethylmaleimide / Q000494:pharmacology; D008861:Microsomes / Q000378:metabolism*; D010716:Phosphatidylinositols / Q000494:pharmacology; D011817:Rabbits
D003902:Detergents; D010716:Phosphatidylinositols; D000251:Adenosine Triphosphatases; D005033:Ethylmaleimide; D002118:Calcium
Do pytannia pro mekhanizm transportu ĭoniv kal'tsiiu u fraktsiï mikrosom mozku