title: Antiviral activity in interferon-treated bovine tracheal organ cultures.
abstract: The effect of bovine interferon on the replication of infectious bovine rhinotracheitis virus and vesicular stomatitis virus in bovine tracheal organ cultures was studied. After treatment of tracheal organ cultures with interferon, inhibition of infectious bovine rhinotracheitis virus and vesicular stomatitis virus replication was observed. This tracheal organ system may be useful in determining the in vivo response to interferon for viral infections of the bovine respiratory tract.
mesh_terms: D000818:Animals; D002417:Cattle; D007242:Herpesvirus 1, Bovine; D007372:Interferons / Q000494:pharmacology*; D009924:Organ Culture Techniques; D014132:Trachea; D014721:Vesicular stomatitis Indiana virus; D014777:Virus Diseases / Q000382:microbiology; D014779:Virus Replication
chemical_list: D007372:Interferons