title: Histochemical localization of opiate receptors and opioid peptides.
abstract: It is possible to localize opiate receptors by histochemical methods. They appear in high densities in anatomical areas associated with physiologic functions altered by opiates. They appear to mediate inhibitory responses; some of them, in certain regions could be involved in axo-axonic synapses. The immunohistochemical studies as well as the electrophysiologic results are compatible with the view that the enkephalins are the endogenous substrates for the opiate receptors.
mesh_terms: D000818:Animals; D001345:Autoradiography; D001369:Axons / Q000032:analysis; D001665:Binding Sites; D001923:Brain Chemistry; D004174:Diprenorphine / Q000032:analysis; D004594:Electrophysiology; D004745:Enkephalins / Q000032:analysis; D005455:Fluorescent Antibody Technique; D006651:Histocytochemistry; D010455:Peptides / Q000032:analysis*; D051381:Rats; D017981:Receptors, Neurotransmitter / Q000032:analysis; D011957:Receptors, Opioid / Q000032:analysis*; D013116:Spinal Cord / Q000032:analysis
chemical_list: D004745:Enkephalins; D010455:Peptides; D017981:Receptors, Neurotransmitter; D011957:Receptors, Opioid; D004174:Diprenorphine