Test method for determination of virucidal efficacy of liquid surface disinfectants.
A test method was developed incorporating AOAC use-dilution stainless steel Penicylinders and H.Ep.-2 tissue culture cells for the evaluation of disinfectants as virucides. The subsequent collaborative study using Herpes simplex and poliovirus type 1 in evaluation against a quaternary ammonium compound, phenolic, and iodiphor disinfectants indicated that the basic test procedure is sound. However, an improved virus concentration technique and a modified method for drying virus-contaminated cylinders are recommended. In addition, other types of disinfectants and test viruses should be included in order to demonstrate that the procedure is versatile as well as reproducible.
D000998:Antiviral Agents; D004202:Disinfectants / Q000494:pharmacology*; D008722:Methods; D017955:Poliovirus / Q000187:drug effects; D018139:Simplexvirus / Q000187:drug effects; D013501:Surface-Active Agents / Q000494:pharmacology*
D000998:Antiviral Agents; D004202:Disinfectants; D013501:Surface-Active Agents