Scintigraphic visualization of myocardial infarcts in baboons using thallium-201 and  technetium-99m pyrophosphate.
4 baboons with myocardial infarcts were evaluated using thallium-201 for myocardial imaging and 99Tcm pyrophosphate for infarct visualization. Scintiphotographic findings were compared with the size of myocardial infarcts calculated from measurements of the activity of MB isoenzymes of creatine kinase (CK-MB) in serum and in the myocardium at autopsy, as described by Sobel's method. Lack of thallium-201 accumulation was noted in left ventricular infarcts of 3 of the 4 baboons. These same areas localized 99Tcm pyrophosphate administered 24--30 h after infarction.
D000818:Animals; D003402:Creatine Kinase / Q000378:metabolism; D011756:Diphosphates; D000882:Haplorhini; D007527:Isoenzymes / Q000378:metabolism; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D010215:Papio; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013667:Technetium; D013793:Thallium
D011756:Diphosphates; D007527:Isoenzymes; D011868:Radioisotopes; D013667:Technetium; D013793:Thallium; D003402:Creatine Kinase