Proliferation of cells and intracellular c-AMP content: comparative investigations of autologous lymphatic cells from palatine tonsils, nasopharyngeal tonsils, and blood.
The c-AMP content and thymidine incorporation were determined in tonsillogenic, adenoid, and peripheral lymphatic cells. A significant c-AMP decrease with simultaneous increase of the thymidine incorporation compared to the blood lymphocytes was noted in the tonsillogenic and adenoid cells. The negative regulative effect of c-AMP on cell proliferation and the function of tonsils at this processes are discussed.
D000234:Adenoids / Q000378:metabolism*; D000293:Adolescent; D002455:Cell Division / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D000242:Cyclic AMP / Q000378:metabolism* / Q000494:pharmacology; D004247:DNA / Q000096:biosynthesis; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism; D014066:Palatine Tonsil / Q000378:metabolism*
D004247:DNA; D000242:Cyclic AMP