In vivo antiviral activity of D-glucosamine.
Intraperitoneal treatments with D-glucosamine, an inhibitor of the glycosylation of the viral envelope, decreased the growth rate of tumors induced in quails or in chicks by Rous sarcoma virus and increased the survival of mice inoculated with human influenza virus.
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001358:Avian Sarcoma Viruses / Q000187:drug effects; D002645:Chickens; D005622:Friend murine leukemia virus; D005944:Glucosamine / Q000494:pharmacology / Q000627:therapeutic use*; D009980:Influenza A virus; D007274:Injections, Intraperitoneal; D007942:Leukemia, Experimental / Q000517:prevention & control*; D008297:Male; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000517:prevention & control*; D011784:Quail; D001357:Sarcoma, Avian / Q000517:prevention & control*; D013237:Stereoisomerism
D000998:Antiviral Agents; D005944:Glucosamine