[Treatment of the syndrome of inappropriate secretion of antidiuretic hormone with demethylchlortetracycline. Apropos of 2 cases].
Two cases of inappropriate antidiuresis are reported, one associated with small cell anaplastic bronchial carcinoma, the other secondary to acute hydrocephalus. ttreatment with demethylchlortetracycline proved effective in both cases. Treatment of the inappropriate antidiuretic syndrome is discussed and the advantages of demethylchlortetracycline emphasised. This antibiotic seems to represent the treatment of choice of the chronic syndrome of inappropriate antidiuresis.
D000368:Aged; D001984:Bronchial Neoplasms / Q000150:complications; D002648:Child; D003707:Demeclocycline / Q000627:therapeutic use*; D006801:Humans; D006849:Hydrocephalus / Q000150:complications; D007010:Hyponatremia / Q000188:drug therapy*; D008297:Male; D009994:Osmolar Concentration; D010900:Pituitary Diseases / Q000188:drug therapy*; D014667:Vasopressins / Q000172:deficiency* / Q000378:metabolism
D014667:Vasopressins; D003707:Demeclocycline
Traitement du syndrome d'antidiurèse inappropriée par la déméthylchlortétracycline