Susceptibility of common marmosets (Callithrix jacchus) to oncogenic and attenuated strains of Herpesvirus saimiri.
Adult common marmosets, inoculated with either of 2 oncogenic Herpesvirus saimiri (HVS) strains, developed fatal lymphoproliferative disease within 23-25 days post inoculation (PI). The disease was identical to HVS-induced lymphoma in cotton-topped and white-lipped marmosets. Common marmosets inoculated with an attenuated HVS strain developed persistent infection; virus has been recovered from cocultivated lymphocytes of these animals for more than 384 days PI.
D000818:Animals; D000914:Antibodies, Viral; D002143:Callitrichinae; D000882:Haplorhini; D006566:Herpesviridae Infections / Q000209:etiology*; D006567:Herpesvirus 2, Saimiriine / Q000276:immunology / Q000302:isolation & purification; D008214:Lymphocytes / Q000382:microbiology; D008223:Lymphoma / Q000209:etiology*; D009374:Neoplasms, Experimental / Q000209:etiology; D013045:Species Specificity; D014412:Tumor Virus Infections / Q000209:etiology*
D000914:Antibodies, Viral