title: The thermodynamic basis of nucleic acid synthesis: energetic considerations in phosphodiester bond formation, secondary structural interactions, and pyrophosphate hydrolysis.
mesh_terms: D000227:Adenine Nucleotides / Q000378:metabolism; D003090:Coliphages / Q000378:metabolism; D004277:DNA, Single-Stranded / Q000096:biosynthesis; D004279:DNA, Viral / Q000378:metabolism; D004259:DNA-Directed DNA Polymerase / Q000378:metabolism; D003854:Deoxyribonucleotides / Q000378:metabolism; D007700:Kinetics; D046911:Macromolecular Substances; D008954:Models, Biological; D008970:Molecular Weight; D009243:NAD / Q000378:metabolism; D009696:Nucleic Acids / Q000096:biosynthesis*; D009841:Oligonucleotides / Q000378:metabolism; D010755:Organophosphates / Q000378:metabolism*; D009943:Organophosphorus Compounds / Q000378:metabolism*; D011119:Polynucleotides / Q000096:biosynthesis; D011336:Probability; D013698:Templates, Genetic; D013816:Thermodynamics; D014158:Transcription, Genetic
chemical_list: D000227:Adenine Nucleotides; D004277:DNA, Single-Stranded; D004279:DNA, Viral; D003854:Deoxyribonucleotides; D046911:Macromolecular Substances; D009696:Nucleic Acids; D009841:Oligonucleotides; D010755:Organophosphates; D009943:Organophosphorus Compounds; D011119:Polynucleotides; D009243:NAD; D004259:DNA-Directed DNA Polymerase