title: [Clinical aspects of trophoblastic tumors].
abstract: Trophoblastic tumors are among the rare diseases in this country. The most important clinical aspects are demonstrated by references and personal experiences in the treatment of trophoblastic tumors. In many countries (SU, USA, GB, Japan) the treatment of trophoblastic tumors has been centralized.--The therapeutical strategy is based on histology, stage and other important prognostic factors. Most important is chemotherapy with antineoplastic substances. Surgery and radiation are to be used only under appropriate indication. After treatment the control of the HCG-values by radioimmunassay is of high importance for the early diagnosis of relapse.--All facts demonstrate, that also in the GDR a stronger centralization of the treatment of trophoblastic tumors should be attained.
mesh_terms: D002822:Choriocarcinoma / Q000150:complications; D006063:Chorionic Gonadotropin / Q000032:analysis; D003609:Dactinomycin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D015122:Mercaptopurine / Q000627:therapeutic use; D008727:Methotrexate / Q000627:therapeutic use; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D011247:Pregnancy; D011379:Prognosis; D014328:Trophoblastic Neoplasms / Q000188:drug therapy / Q000473:pathology*; D014594:Uterine Neoplasms / Q000473:pathology*
chemical_list: D006063:Chorionic Gonadotropin; D003609:Dactinomycin; D015122:Mercaptopurine; D008727:Methotrexate
vernacular_title: Zur Klinik der Trophoblasttumoren.