[Early effect of poliomyelitis virus on 5'-nucleotidase activity in HeLa cells].
One of the earlier effects of poliovirus was the maintaining of a high level of Hela cells 5'-nucleotidase activity (maximal efficiency for a virus/cell ratio = 500 ID 50/cell) (ID50:50% Infections Dose). The activity decreased when cells were suspended in the presence of EDTA(EDTA:Ethylene Diamine Tetracetic Acid) and was partially restored by adding 10 mM Mg++ interactions are discussed.
D004492:Edetic Acid / Q000494:pharmacology; D006367:HeLa Cells / Q000201:enzymology*; D007700:Kinetics; D008274:Magnesium / Q000494:pharmacology; D009708:Nucleotidases / Q000378:metabolism*; D017955:Poliovirus
D004492:Edetic Acid; D009708:Nucleotidases; D008274:Magnesium
Action précoce du virus poliomyélitique sur l'activité 5'-nucléotidase des cellules HeLa.