Direct measurement of cGMP in blood plasma and urine by radioimmunoassay.
Antisera, raised against 2'-O-succinyl-cGMP conjugated to ovalbumin or kehole limpet haemocyanin, have been used to develop radioimmunoassays for the direct determination of urine and plasma cGMP levels. Details of these assays are presented, together with evidence for their validity.
D000818:Animals; D001666:Binding Sites, Antibody; D006152:Cyclic GMP / Q000097:blood* / Q000276:immunology / Q000652:urine; D006433:Hemocyanins / Q000276:immunology; D007106:Immune Sera; D011817:Rabbits; D011863:Radioimmunoassay
D007106:Immune Sera; D006433:Hemocyanins; D006152:Cyclic GMP