title: delta9 Desaturase activity in normal mouse liver and hepatoma SS1K.
abstract: The activity of delta9 desaturase was determined in the microsomal fraction of normal mouse liver and hepatoma SS1K in the presence of the 105,000 x g supernatant. Neither hepatic nor hepatoma soluble fractions were able to modify the low desaturating capacity. Two enzymes from the microsomal electron transport chain associated with delta9 desaturase, namely NADH-cytochrom b5 reductase and NADH-cytochrom C reductase were also measured. The results indicate that the low delta9 desaturase activity in hepatoma SS1K could be related to the reduced amount of desaturase.
mesh_terms: D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000201:enzymology*; D003579:Cytochrome Reductases / Q000378:metabolism; D044943:Fatty Acid Desaturases / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D008113:Liver Neoplasms / Q000201:enzymology*; D008297:Male; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology; D009374:Neoplasms, Experimental / Q000201:enzymology
chemical_list: D044943:Fatty Acid Desaturases; D003579:Cytochrome Reductases