Stimulation of glucagon and inhibition of insulin secretion evoked from carotid baroreceptors.
The influence from carotid baroreceptors on portal immuno-reactive glucagon and insulin levels and on arterial plasma glucose concentration was studied in vagotomized cats by sectioning of the sinus nerves. Such a complete elimination of the afferent baroreceptor discharge caused a prompt and pronounced increase in the glucose and glucagon levels, whereas the insulin concentration significantly decreased. The role of vascular barorecptors in the hyperglycemic response to hemorrhage is discussed.
D000818:Animals; D002344:Carotid Body / Q000502:physiology*; D002415:Cats; D005934:Glucagon / Q000097:blood*; D007328:Insulin / Q000097:blood*; D007700:Kinetics; D011956:Receptors, Cell Surface / Q000502:physiology*; D014628:Vagotomy
D007328:Insulin; D011956:Receptors, Cell Surface; D005934:Glucagon