Hemangiosarcoma and hepatocellular carcinoma of the liver following vinyl chloride exposure. A report of two cases.
A report is given of the clinical and autopsy findings of two men who died from malignant liver neoplasm following occupational exposure to vinyl chloride. The first patient was a 44-year-old man with an hemangiosarcoma of the liver, the second patient a 67-year-old man with an hepatocellular carcinoma. So far an hepatocellular carcinoma due to vinyl chloride has not yet been observed in man. Its occurrence, however, has been suggested from the results of animal experiments. The connection of hepatocellular carcinoma with exposure to vinyl chloride is discussed.
D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000139:chemically induced* / Q000473:pathology; D006394:Hemangiosarcoma / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced; D014752:Vinyl Chloride / Q000506:poisoning*; D014753:Vinyl Compounds / Q000506:poisoning*
D014753:Vinyl Compounds; D014752:Vinyl Chloride