title: Recovery of reovirus type 2 from an immature dog with respiratory tract disease.
abstract: Two similar cytopathic agents were recovered from the throat and rectal swab specimens of an immature dog with upper respiratory tract disease. The reference isolate, 14-72R, was shown to be a member of the reovirus group by its physicochemical properties, cytopathic effects in cell cultures, and appearance when examined in the electron microscope. Both isolates hemagglutinated human type O erythrocytes and antigenically were closely related to reovirus type 2. The affected pup had an increase in antibody titer to reovirus types 2 and 3. The latter findings provide evidence for possible heterotypic antibody responses in dogs to reovirus infection.
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D003588:Cytopathogenic Effect, Viral; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D012087:Reoviridae / Q000254:growth & development / Q000302:isolation & purification* / Q000648:ultrastructure; D012088:Reoviridae Infections / Q000382:microbiology / Q000662:veterinary*; D012141:Respiratory Tract Infections / Q000382:microbiology / Q000662:veterinary*