Microtubules, cyclic AMP and lysosomal enzyme release. A review.
The importance of microtubules and cyclic AMP in the control of lysosomal enzyme release from polymorphonuclear leukocytes is questioned. The article is a short review of pertinent literature designed to stimulate further research into this important mechanism of inflammation.
D000818:Animals; D003078:Colchicine / Q000627:therapeutic use; D000242:Cyclic AMP / Q000502:physiology*; D006152:Cyclic GMP / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000503:physiopathology*; D008247:Lysosomes / Q000201:enzymology / Q000502:physiology*; D008870:Microtubules / Q000502:physiology*; D009504:Neutrophils / Q000201:enzymology / Q000502:physiology* / Q000648:ultrastructure
D000242:Cyclic AMP; D006152:Cyclic GMP; D003078:Colchicine