Tests in rufiventer and other marmosets of susceptibility to human hepatitis A virus.
The rufiventer marmoset proved equally satisfactory to S. mystax for studies of human hepatitis A virus. C. jacchus, C. argentata, S. weddelli, and S. oedipomidas oedipus were not satisfactory. Livers of rufiventer marmosets produced satisfactory CR326 strain hepatitis A antigen for immune adherence tests both in amount and specificity. Rufiventer marmosets infected with human hepatitis A virus showed enzyme elevations and high titers of viral antigen in their livers as early as seven days after viral inoculation, indicating that a primary viral infection can cause hepatitis without need for a secondary autoimmune response to liver tissue.
D000818:Animals; D000917:Antibody Formation; D000956:Antigens, Viral; D002143:Callitrichinae / Q000276:immunology; D000882:Haplorhini; D006507:Hepatovirus / Q000276:immunology / Q000472:pathogenicity*; D008099:Liver / Q000276:immunology / Q000382:microbiology; D013045:Species Specificity
D000956:Antigens, Viral