[Inhibition of corticotropic function by administration of GABA in carp (Cyprinus carpio L.)].
The intracardiac injection (50 microgram/g) of GABA to Carps clearly inhibits the rise of the plasma cortisol level which occurs usually in response to the blood sampling manipulations. The inhibition starts thirty minutes after injection and lasts till the end of the experiment two hours later. The hypothesis that this neurotransmitter has a regulatory function on the corticotrop cells, especially on the excretion of ACTH has to be considered.
D000302:Adrenal Cortex / Q000187:drug effects / Q000502:physiology*; D000324:Adrenocorticotropic Hormone / Q000502:physiology; D000613:Aminobutyrates / Q000494:pharmacology*; D000818:Animals; D002347:Carps; D006854:Hydrocortisone / Q000097:blood*; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
D000613:Aminobutyrates; D005680:gamma-Aminobutyric Acid; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
Inhibition de la fonction corticotrope par l'administration de GABA chez la carpe (Cyprinus carpio L.).