[Thymidine phosphorylation with the participation of rat thymic and hepatic thymidine kinase in the presence of a factor from Cl. perfringens (welchii)].
Factor CPW, isolated from Cl. perfringens/welchii was shown to activate latent thymidine kinase (factor N) from liver tissue of rats beginning from 42 days age. CPW factor activated 3.5-fold also thymidine kinase from rat strumous gland; the enzyme was observed during involution of the tissue. The data suggest that increase in thymidine kinase activity in proliferating tissues is related to activation of latent enzymes.
D000367:Age Factors; D000818:Animals; D001426:Bacterial Proteins / Q000302:isolation & purification / Q000494:pharmacology*; D003016:Clostridium perfringens; D004789:Enzyme Activation / Q000187:drug effects; D008099:Liver / Q000201:enzymology; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D051381:Rats; D013936:Thymidine / Q000378:metabolism*; D013937:Thymidine Kinase / Q000378:metabolism*; D013950:Thymus Gland / Q000201:enzymology
D001426:Bacterial Proteins; D013937:Thymidine Kinase; D013936:Thymidine
Fosforilirovanie timidina s uchastiem timidinkinazy iz zobnoĭ zhelezy i pecheni krys v prisutstvii faktora iz Cl. perfringens (welchii).