Antigenic relationship between human and bovine rotaviruses as determined by neutralization, immune adherence hemagglutination, and complement fixation tests.
Guinea pig antiserum to bovine rotavirus does not neutralize human rotavirus. Bovine and human rotaviruses were, however, extensively cross-reactive when examined by complement fixation and immune adherence hemagglutination tests with antiserum to either virus. The immune adherence hemagglutination test was 16- to 32-fold more sensitive than the complement fixation test in detecting rotavirus.
D000818:Animals; D000956:Antigens, Viral; D002417:Cattle; D003168:Complement Fixation Tests; D003429:Cross Reactions; D006168:Guinea Pigs; D006801:Humans; D007104:Immune Adherence Reaction; D007106:Immune Sera / Q000494:pharmacology; D009500:Neutralization Tests; D012328:RNA Viruses / Q000276:immunology*; D012401:Rotavirus / Q000276:immunology*
D000956:Antigens, Viral; D007106:Immune Sera