[The effect of nalorphine on analgesia induced by peripheral stimulation].
The blockade of effects induced by percutaneous peripheral stimulation were abolished by injection of an opiate antagonist as nalorphine. Our results lead to the hypothesis that central and peripheral stimulations act by the same mechanism in producing blockade of noxious impulses. One may suggest that peripheral stimulations induce release of endogenous morphine-like substances which in turn give descending inhibition.
D000698:Analgesia; D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D009269:Nalorphine / Q000494:pharmacology*; D009619:Nociceptors / Q000187:drug effects*; D010525:Peripheral Nerves / Q000502:physiology; D011957:Receptors, Opioid / Q000187:drug effects*; D009435:Synaptic Transmission / Q000187:drug effects
D011957:Receptors, Opioid; D009269:Nalorphine
Effets de la nalorphine sur les analgésies induites par stimulations périphériques.