title: Reproduction and treatment of necrotic enteritis in broilers.
abstract: A change in ration from one containing 50% fish meal to a standard chick starter containing 10(8) Clostridium perfringens/g of feed resulted in the production of necrotic enteritis in 2-week-old broiler chicks. Lincomycin added to the inoculated ration at a concentration of 20 g/907.2 kg significantly reduced mortality in the chicks. Inoculation of broth cultures of C perfringens directly into the duodenum, using a surgically inserted tetrafluoroethylene resin tube, indicated a relationship existed between the number of C perfringens inoculated and the gross lesions. The disease could be consistently produced by this technique.
mesh_terms: D000821:Animal Feed; D000818:Animals; D002645:Chickens; D003015:Clostridium Infections / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D003016:Clostridium perfringens; D004751:Enteritis / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D008034:Lincomycin / Q000627:therapeutic use; D008297:Male; D009336:Necrosis; D011201:Poultry Diseases / Q000188:drug therapy / Q000209:etiology
chemical_list: D008034:Lincomycin