The ultrastructure of malignant fibrous histiocytoma (case report).
A soft tissue malignant fibrous histiocytoma was studied by light and electron microscopy. The presence of fibroblast-like cells, histiocyte-like cells, undifferentiated stem cells, and xanthomatous cells was confirmed. Fibroblast- and histiocyte-like multinucleated giant cells were also observed. The observation of lysosomes in some fibroblast-like cells, the features of undifferentiated stem cells, and the presence of cells and intermediate characteristics common to xanthomatous, histiocytic, and stem cells suggest a strict relationship among these cellular types.
D000293:Adolescent; D005347:Fibroblasts / Q000648:ultrastructure; D005487:Foam Cells / Q000648:ultrastructure; D006412:Hematopoietic Stem Cells / Q000648:ultrastructure; D006644:Histiocytes / Q000648:ultrastructure; D018219:Histiocytoma, Benign Fibrous / Q000648:ultrastructure*; D006801:Humans; D008297:Male; D012983:Soft Tissue Neoplasms / Q000648:ultrastructure*