Cushing's disease in a child with lymphosarcoma and acute leukemia.
A 6-year-old girl with lymphosarcoma developed Cushing's syndrome. Suppression-stimulation studies verified adrenal hyperfunction secondary to bilateral adrenocortical hyperplasia, and the course suggested the possibility of "ectopic ACTH" production by the neoplasm as the etiology.
D000302:Adrenal Cortex; D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D002648:Child; D003480:Cushing Syndrome / Q000209:etiology* / Q000473:pathology; D005260:Female; D006729:Hormones, Ectopic / Q000378:metabolism; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006965:Hyperplasia; D007945:Leukemia, Lymphoid / Q000150:complications*; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D009384:Paraneoplastic Endocrine Syndromes
D006729:Hormones, Ectopic; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone