Ultrastructural cytology of prostate carcinoma cells from Wistar rats.
Cells from spontaneous adenocarcinomas of the prostate (Pollard, M.: J. Natl. Cancer Inst. 51: 1235, 1973) in aged Lobund Wistar rats were examined by electron microscopy. Cytologic structures of the rat prostate tumor cells resembled analogous structures from human prostate tumor cells. These findings support the prospect that the rat prostate tumor will provide a model system of prostate cancer in man.
D000230:Adenocarcinoma / Q000648:ultrastructure*; D000818:Animals; D002462:Cell Membrane / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D004195:Disease Models, Animal; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D008297:Male; D008928:Mitochondria / Q000648:ultrastructure; D009374:Neoplasms, Experimental / Q000648:ultrastructure; D011471:Prostatic Neoplasms / Q000648:ultrastructure*; D051381:Rats