Effect of SCH 15280, a new bronchodilator, on cyclic 3',5'-nucleotide phosphodiesterase activity and cyclic 3',5'-adenosine monophosphate levels in guinea pig lung.
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors / Q000378:metabolism; D000628:Aminophylline / Q000494:pharmacology; D000818:Animals; D001578:Benzopyrans / Q000494:pharmacology*; D001993:Bronchodilator Agents / Q000494:pharmacology*; D002049:Burimamide / Q000494:pharmacology; D002744:Chlorpheniramine / Q000494:pharmacology; D000242:Cyclic AMP / Q000378:metabolism*; D006152:Cyclic GMP; D004347:Drug Interactions; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology; D066298:In Vitro Techniques; D007700:Kinetics; D008168:Lung / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D010726:Phosphodiesterase Inhibitors; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D011725:Pyridines / Q000494:pharmacology*
D001578:Benzopyrans; D001993:Bronchodilator Agents; D010726:Phosphodiesterase Inhibitors; D011725:Pyridines; D000628:Aminophylline; D002744:Chlorpheniramine; C009983:azanator; D006632:Histamine; D000242:Cyclic AMP; D010727:Phosphoric Diester Hydrolases; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D006152:Cyclic GMP; D002049:Burimamide