Splenoperitoneal anastomoses after application of collagenase to the splenic capsule of rats.
In 200 Wistar rats the spleen was transposed into a pouch between the muscle layers of the left abdominal wall. Collagenase powder was applied to the spleen surface. After 12 to 24 hours an acute haemorrhagic inflammation was seen. Collaterals developed from the splenic parenchyma to the abdominal wall from the 10th day. They connected the portal venous system with the caval system.
D000009:Abdominal Muscles / Q000098:blood supply; D000818:Animals; D003094:Collagen; D003097:Collateral Circulation; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced; D007249:Inflammation / Q000139:chemically induced; D003012:Microbial Collagenase / Q000494:pharmacology*; D009132:Muscles / Q000473:pathology; D009336:Necrosis; D010537:Peritoneum / Q000098:blood supply*; D051381:Rats; D013154:Spleen / Q000098:blood supply* / Q000187:drug effects; D013997:Time Factors
D003094:Collagen; D003012:Microbial Collagenase