The fate of protein subunits of parainfluenza (Sendai) virus after adsorption to NIL8 hamster embryo cells.
Adsorption of u.v.-inactivated Sendai virus on to NIL8 hamster cells causes fusion of the cells into polykaryocytes within 2 h. "Infected" cells were incubated at 37 degrees C for periods of 10 min to 8 h and their surface proteins iodinated with [125I] catalysed by peroxidase. Structural components of the viral envelope, such as haemagglutin-neuraminidase (HN) and probably also the fusion protein (F) were detected in the cell membrane for periods up to 4 h post infection.
D000327:Adsorption; D000956:Antigens, Viral / Q000032:analysis*; D002459:Cell Fusion; D002462:Cell Membrane / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D007124:Immunoenzyme Techniques; D010222:Parainfluenza Virus 1, Human / Q000276:immunology / Q000378:metabolism*; D014764:Viral Proteins / Q000276:immunology / Q000378:metabolism*
D000956:Antigens, Viral; D014764:Viral Proteins