Electron spin resonance studies of radicals obtained by the reaction of alpha-tocopherol and its model compound with superoxide ion.
alpha-Tocopherol (vitamin E) and its model compound, 6-hydroxy-2,2,5,7,8-pentamethylchroman, were found to be oxidized by O2- to yield free radicals which were detected at room temperature by ESR spectroscopy. The ESR spectra of these radicals showed seven main lines with additional hyperfine structure and have the same g-values at 2.0046. Assignments of the ESR spectra were done on the basis of the spectra of the free radicals of deuterated hydroxypentamethylchroman obtained from the same reaction with O2-. The radicals observed are chromanoxyls generated by the abstraction of hydrogen from the 6-hydroxy group of tocopherols.
D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D008956:Models, Chemical; D010100:Oxygen; D013481:Superoxides; D014810:Vitamin E
D005609:Free Radicals; D013481:Superoxides; D014810:Vitamin E; D010100:Oxygen