[Demonstration of specific receptors for angiotensin III in rat adrenal glands].
Distinct and specific binding sites for 3H-angiotensin II (A II) AND 3H-angiotensin III (A III) have been demonstrated in Rat adrenal gland preparations. A III binding sites have the highest affinity (KD29C1-2.10(-10)M) for the 2-8 heptapeptide. This suggests the possibility of a separate and distinct physiological role for the 2-8 heptapeptide, mediated via such A III binding sites.
D000804:Angiotensin II / Q000031:analogs & derivatives* / Q000378:metabolism*; D000805:Angiotensin III / Q000378:metabolism*; D000818:Animals; D001667:Binding, Competitive; D007700:Kinetics; D051381:Rats; D011945:Receptors, Angiotensin / Q000378:metabolism*; D011956:Receptors, Cell Surface / Q000378:metabolism*
D011945:Receptors, Angiotensin; D011956:Receptors, Cell Surface; D000804:Angiotensin II; D000805:Angiotensin III
Démonstration de récepteurs spécifiques de l'angiotensine III dans les surrénales de rat