title: Adjuvant systemic therapy in "early" breast cancer.
abstract: "Early" breast cancer is a systemic disease in the majority of cases. Progress has been and is being made toward the determination of those women at risk of recurrence. Attractive as it seems, the value of systemic adjuvant therapy, given at the time of minimal tumour load i.e., after mastectomy, is not proven. Therefore, for the average case it is better to treat the cancer locally and to observe and leave further evaluation of systemic therapy to those centres which are able to conduct controlled, randomized trails.
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D002369:Castration; D005260:Female; D006801:Humans; D007167:Immunotherapy; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D011956:Receptors, Cell Surface
chemical_list: D000970:Antineoplastic Agents; D011956:Receptors, Cell Surface