[Age and changes in the activity of several energy metabolism enzymes in the rabbit aorta].
Age alterations in the activity of several key enzymes of glucose oxidative breakdown (hexokinase, glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and cytochrome c oxidase) were studied in extracts from rabbit aorta. The hexokinase activity was measured also in mitochondrial fraction. The activity of all the enzymes studied in rabbit aorta (calculated either per 1 g of the tissue or per 1 mg of proteins) was the highest at the age from 1-2 weeks to 1 month. The minimal activity was observed in adult animals, which were 1-2 years old, In aorta of 3,5-4 years old rabbits an increase (per 1 g of the tissue) in the activity of the enzymes was observed.
D000375:Aging; D000818:Animals; D001011:Aorta / Q000201:enzymology* / Q000648:ultrastructure; D002682:Chinchilla; D003576:Electron Transport Complex IV / Q000378:metabolism; D004734:Energy Metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006593:Hexokinase / Q000378:metabolism; D008928:Mitochondria / Q000201:enzymology; D010734:Phosphogluconate Dehydrogenase / Q000378:metabolism; D011817:Rabbits
D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D003576:Electron Transport Complex IV; D006593:Hexokinase
Vozrastnye izmeneniia aktivnosti nekotoroykh fermentov énergeticheskogo obmena v aorte krolika.