title: [Sharp's syndrome (mixed connective tissue disease). Clinical aspects diagnosis and prognosis].
abstract: Sharp syndrome (mixed connective tissue disease) is a distinct rheumatic syndrome with symptoms of various connective tissue diseases (rheumatoid arthritis, systemic lupus erythematodes, progressive systemic sclerosis, polymyositis and others). 15 patients with mixed connective tissue disease are described. The clinical picture and diagnostic criteria are evaluated and the course of the disease, treatment and prognosis are discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis; D000914:Antibodies, Viral / Q000032:analysis; D001172:Arthritis, Rheumatoid / Q000150:complications; D002648:Child; D003095:Collagen Diseases; D003587:Cytomegalovirus / Q000276:immunology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008875:Middle Aged; D009220:Myositis / Q000150:complications; D011379:Prognosis; D012595:Scleroderma, Systemic / Q000150:complications; D013577:Syndrome
chemical_list: D000974:Antibodies, Antinuclear; D000914:Antibodies, Viral
vernacular_title: Das Sharp-Syndrom ("mixed connective tissue disease"). Klinik, Dianose und Verlauf.