Urinary content of 3',5'-adenosine monophosphate (cAMP) and creatinine in full-term and premature infants.
Cyclic 3',5'-monophosphate (c-AMP) and creatinine were measured in full-term and premature infants. In normals, values for c-AMP were highest on days 1 and 2 (1.3-1.5 nmol/ml) and decreased thereafter. In prematures the c-AMP values were significantly lower than in the full-term infants. There was a rough correlation with birth weight. Creatinine values were closely reflected by the c-AMP levels. Changes found in neonatal jaundice, hypocalcaemia, respiratory distress syndrome, and anoxia could be attributed to prematurity. No diurnal variation in c-AMP values was found.
D003404:Creatinine / Q000652:urine*; D000242:Cyclic AMP / Q000652:urine*; D005260:Female; D005311:Fetal Hypoxia / Q000652:urine; D006801:Humans; D006996:Hypocalcemia / Q000652:urine; D007231:Infant, Newborn; D007234:Infant, Premature; D007567:Jaundice, Neonatal / Q000652:urine; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000652:urine
D003404:Creatinine; D000242:Cyclic AMP