title: Hypothalamo-pituitary-adrenal function in pituitary adenoma and craniopharyngioma. Part I: Insulin test, lysine-vasopressin test, and rapid ACTH test.
abstract: For the assessment of hypothalamo-pituitary-adrenal function in the presence of pituitary adenomas and craniopharyngiomas, insulin tests, lysine-vasopressin tests, and rapid ACTH tests were performed and plasma cortisol was assayed. Rapid ACTH test and lysine-vasopressin test, which examine adrenal and mainly pituitary function respectively, showed normal function in ten among 14 cases. But insulin test, which examines the whole hypothalamo-pituitary-adrenal function, showed various levels of abnormality in eight among 14 cases. Frequent association of functional disturbances of this axis in these diseases was stressed.
mesh_terms: D000238:Adenoma, Chromophobe / Q000175:diagnosis* / Q000503:physiopathology; D000293:Adolescent; D000324:Adrenocorticotropic Hormone; D000328:Adult; D000368:Aged; D002648:Child; D003397:Craniopharyngioma / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology; D007328:Insulin; D008236:Lypressin; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000503:physiopathology; D010913:Pituitary-Adrenal System / Q000503:physiopathology; D014667:Vasopressins / Q000031:analogs & derivatives*
chemical_list: D007328:Insulin; D014667:Vasopressins; D008236:Lypressin; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone