[A study of pancreatic insulinomas by electron microscopy. 9 cases (author's transl)].
Nine hypoglycaemia-inducing pancreatic tumours were studied by electron microscopy. In 8 of these tumours, it was possible to identify, within the cell cytoplasm, secretory granules with a "paracrystalline" content, identical in appearance to the granules of the B cell of the normal human pancreas. Thus electron microscopy would appear to be a reliable and sensitive method for the morphological identification of these endocrine tumours of the pancreas.
D007516:Adenoma, Islet Cell / Q000378:metabolism / Q000648:ultrastructure*; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D007515:Islets of Langerhans / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D010190:Pancreatic Neoplasms / Q000378:metabolism / Q000648:ultrastructure*
Insulinomes pancréatiques. Etude en microscopie électronique, 9 cas.