Variation of properties of chrysotile asbestos subjected to milling.
Mechanical milling is commonly used to produce short chrysotile asbestos for experimental purposes. Such manipulation also decreases fiber crystallinity, alters Si-O and Mg-O interlayer bonding, induces coordination changes in the brucite layer, diminishes the ability of fiber to reduce specific free radicals and physisorb organic molecules, and decreases hemolytic potency and antagonist sorption capabilities. The degree of alteration is related to the time of milling. Results of biological experimentation with these materials must be interpreted with caution. Interaction mechanisms in the biological setting are suggested for chrysotile fiber.
D000818:Animals; D001194:Asbestos / Q000032:analysis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D006461:Hemolysis / Q000187:drug effects; D066298:In Vitro Techniques; D008854:Microscopy, Electron; D010316:Particle Size; D012756:Sheep; D013053:Spectrophotometry; D014961:X-Ray Diffraction
D005609:Free Radicals; D001194:Asbestos