The effects of formocresol on rat sponge implant tissue: a biochemical study.
An investigation was conducted on the effect of formocresol treatment of the aqueous extractability and enzymatic susceptibility of excised implant tissue. The treated tissue demonstrated a decreased solubility and a diminished digestibility by trypsin, pepsin and collagenase. However, its reactivity toward hyaluronidase showed little alteration.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D003094:Collagen / Q000032:analysis; D003238:Connective Tissue / Q000187:drug effects*; D005566:Formocresols / Q000494:pharmacology*; D006821:Hyaluronoglucosaminidase / Q000494:pharmacology; D003012:Microbial Collagenase / Q000494:pharmacology; D010434:Pepsin A / Q000494:pharmacology; D051381:Rats; D012995:Solubility; D014357:Trypsin / Q000494:pharmacology
D000596:Amino Acids; D005566:Formocresols; D003094:Collagen; D006821:Hyaluronoglucosaminidase; D014357:Trypsin; D010434:Pepsin A; D003012:Microbial Collagenase