Ammonium chloride inhibits cell fusion induced by syn mutants of herpes simplex virus type 1.
Cell fusion induced by syn mutants of herpes simplex virus type 1 is inhibited by NH4Cl. The inhibition of fusion is both rapid and rapidly reversible and apprears to be due to the NH4+ ion. Virus production was not significantly altered by NH4Cl, although cell growth was greatly diminished.
D000643:Ammonium Chloride / Q000494:pharmacology*; D002459:Cell Fusion / Q000187:drug effects*; D009154:Mutation; D018139:Simplexvirus / Q000187:drug effects / Q000254:growth & development*; D014779:Virus Replication / Q000187:drug effects
D000643:Ammonium Chloride