Granulocyte collagenase and elastase and the plasma protease inhibitors in human pus.
Granulocyte collagenase and elastase was demonstrated in human pus using specific antisera. The enzymes were complexed by alpha1-antitrypsin and alpha2-macroglobulin but also were present as free proteases. All purulent exudates showed free elastolytic and collagenolytic activity.
D000038:Abscess / Q000201:enzymology; D000906:Antibodies; D000937:Antigen-Antibody Reactions; D006098:Granulocytes / Q000201:enzymology*; D006801:Humans; D007962:Leukocytes / Q000201:enzymology*; D008259:Macroglobulins / Q000032:analysis; D003012:Microbial Collagenase / Q000032:analysis*; D010196:Pancreatic Elastase / Q000032:analysis*; D011480:Protease Inhibitors; D013492:Suppuration / Q000201:enzymology*; D014361:Trypsin Inhibitors / Q000032:analysis
D000906:Antibodies; D008259:Macroglobulins; D011480:Protease Inhibitors; D014361:Trypsin Inhibitors; D010196:Pancreatic Elastase; D003012:Microbial Collagenase