title: ACTH4-10: cognitive and behavioral effects in hyperactive, learning-disabled children.
abstract: A single dose of 30 mg i.m. ACTH4-10 or placebo was given to a sample of 20 hyperactive, learning-disabled children. No significant drug effects were obtained on measures of visual and auditory memory, new learning, impulsivity, attention, perceptual motor skills, anxiety, or behavior during testing. There was a slight increase in pulse rate for drug compared with the placebo group. These findings are in keepeing witth other recent reports of limited or insignificant cognitive effects in adults of a single dose of this peptide.
mesh_terms: D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002648:Child; D005260:Female; D006801:Humans; D006948:Hyperkinesis / Q000188:drug therapy*; D007859:Learning Disabilities / Q000188:drug therapy*; D008297:Male
chemical_list: D000324:Adrenocorticotropic Hormone