Strand scission of DNA by bound adriamycin and daunorubicin in the presence of reducing agents.
D001665:Binding Sites; D004270:DNA, Circular / Q000378:metabolism; D004279:DNA, Viral / Q000378:metabolism; D003630:Daunorubicin / Q000378:metabolism / Q000494:pharmacology; D004317:Doxorubicin / Q000378:metabolism / Q000494:pharmacology; D009690:Nucleic Acid Conformation / Q000187:drug effects; D010084:Oxidation-Reduction; D013481:Superoxides
D004270:DNA, Circular; D004279:DNA, Viral; D013481:Superoxides; D004317:Doxorubicin; D003630:Daunorubicin