[Presence of nuclear triiodothyronine (T3) receptors in mouse fibroblasts].
The present preliminary data obtained from intact fibroblasts of adult mice (polyploid stem L 929) suggest that this cell system possesses high-affinity and saturable nuclear binding sites for triiodothyronine. As estimated by the Scatchard analysis, the equilibrium dissociation constant is approximately 2 X 10(-10) moles, the maximal binding capacity is about 2 000 sites for T3 per cell nucleus.
D000818:Animals; D001665:Binding Sites; D002467:Cell Nucleus / Q000378:metabolism; D002478:Cells, Cultured; D005347:Fibroblasts / Q000378:metabolism / Q000648:ultrastructure; D007700:Kinetics; D051379:Mice; D011956:Receptors, Cell Surface / Q000378:metabolism; D014284:Triiodothyronine / Q000378:metabolism
D011956:Receptors, Cell Surface; D014284:Triiodothyronine
Présence de récepteurs nucléaires à la triiodothyronine (T3) dans le fibroblaste de souris.