[Adrenaline and cyclic AMP stimulation of ketopentose and sedoheptulose formation in rat liver homogenates].
Formation of sedoheptulose-7-phosphate and ketopentose phosphate was studied in vitro as affected by epinephrine and cAMP. No effect of epinephrine on the activity of transketolase was found with ribose-5-phosphate as a substrate of the nonoxidative reactions of the pentose phosphate ccyle. Epinephrine and cAMP enhance the formation of ketopentoses and sedoheptulose with glycogen as a main carbohydrate source, which is most pronounced in the experiments with cold preincubation. The phosphorylase system mediate influence of epinephrine and cAMP on the nonoxidative reactions products may be assumed.
D000818:Animals; D000242:Cyclic AMP / Q000494:pharmacology*; D004837:Epinephrine / Q000494:pharmacology*; D006003:Glycogen / Q000378:metabolism; D006539:Heptoses / Q000096:biosynthesis; D008099:Liver / Q000378:metabolism*; D009005:Monosaccharides / Q000096:biosynthesis*; D010429:Pentoses / Q000096:biosynthesis; D051381:Rats
D006539:Heptoses; D009005:Monosaccharides; D010429:Pentoses; D006003:Glycogen; D000242:Cyclic AMP; D004837:Epinephrine
Stimuliatsiia adrenlinom i tsiklicheskoĭ AMF obrazovaniia ketopentoz i sedogeptulezy v gomogenatakh pecheni krys