Transabdominal lymphography after intraperitoneal injection of Rous virus in newborn rats.
Newborn rats were inoculated in the peritoneal cavity with Rous sarcoma virus (Schmidt-Ruppin strain). They were studied lymphographically and histologically after various intervals of time. As a result of lesions of the lymph vessels and nodes, the lymphatic drainage of the peritoneal cavity was increasingly impaired. Pleural effusion developed as a result of leakage through the walls of the lymphatics. The passage through the lymph nodes was blocked and large lymph cysts arose in the mediastinum and retroperitoneally.
D000818:Animals; D000831:Animals, Newborn; D001358:Avian Sarcoma Viruses; D007274:Injections, Intraperitoneal; D008205:Lymphangitis / Q000000981:diagnostic imaging* / Q000209:etiology; D008220:Lymphography / Q000379:methods*; D008297:Male; D008480:Mediastinitis / Q000209:etiology; D010529:Peritoneal Cavity / Q000000981:diagnostic imaging*; D010996:Pleural Effusion / Q000209:etiology; D051381:Rats; D012187:Retroperitoneal Space