Synthesis of as-triazines as potential antiviral agents.
Four acenaphtho[1,2-e]-as-triazines and 11 5,6-diaryl-as-triazines, all substituted with an aliphatic or aromatic amino function in the 3-position, were synthesized. Two acenaphthotriazines were active against vesicular stomatitis virus in tissue culture.
D000818:Animals; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000627:therapeutic use; D004686:Encephalomyocarditis virus; D004769:Enterovirus Infections / Q000188:drug therapy; D008722:Methods; D051379:Mice; D008826:Microbial Sensitivity Tests; D009499:Neutral Red; D014227:Triazines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000627:therapeutic use; D010948:Viral Plaque Assay
D000998:Antiviral Agents; D014227:Triazines; D009499:Neutral Red