[Quantitative analysis of the immunogenic activity of SV40 virus and the cells of tumors induced by this virus].
The study of specific antitumour immunity induced by onogenic SV40 virus and by cell of SV40 virus and by cells of SV40-induced tumour of Syrian hamster demonstrated direct correlation between the level of specific antitumour resistance and the immunizing virus and tumour cell doses. The minimal resistance-inducing dose of the wild type SV40 virus strain was 10 times higher than that of ts A-30 mutant of this virus. Minimal resistance-inducing dose of irradiated cells of the tumour was about 9 x 10(5) cells; a 10-fold increase of this dose significantly increased the specific antitumour immunity level.
D000818:Animals; D000951:Antigens, Neoplasm; D006224:Cricetinae; D066298:In Vitro Techniques; D009374:Neoplasms, Experimental / Q000276:immunology* / Q000517:prevention & control; D013539:Simian virus 40 / Q000276:immunology*; D014611:Vaccination
D000951:Antigens, Neoplasm
Kolichestvennyĭ analiz immunogennoĭ aktivnosti virusa SV40 i kletok opukholi, indutsirovannoĭ étim virusom.