Proinsulin binds to a growth peptide receptor and stimulates DNA synthesis in chick embryo fibroblasts.
D000818:Animals; D002096:C-Peptide / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D002642:Chick Embryo; D004247:DNA / Q000096:biosynthesis*; D005347:Fibroblasts / Q000378:metabolism*; D007328:Insulin / Q000494:pharmacology; D008099:Liver / Q000378:metabolism; D008214:Lymphocytes / Q000378:metabolism; D011384:Proinsulin / Q000378:metabolism / Q000494:pharmacology*; D011485:Protein Binding; D011956:Receptors, Cell Surface / Q000378:metabolism*; D012710:Serum Albumin, Bovine / Q000494:pharmacology; D013936:Thymidine / Q000378:metabolism
D002096:C-Peptide; D007328:Insulin; D011956:Receptors, Cell Surface; D012710:Serum Albumin, Bovine; D004247:DNA; D011384:Proinsulin; D013936:Thymidine