title: Evidence for cyclic AMP-dependent protein kinase activity in isolated guinea pig and rat liver mitochondria.
abstract: Purified preparations of guinea pig and rat liver mitochondria contain considerable latent cAMP-dependent protein kinase activity that is revealed by treatment with 1% Triton X-100. The solubilized kinase was partly purified by DEAE-cellulose chromatography. It accepts protein in the washed Triton-extracted mitochondria as substrate.
mesh_terms: D000818:Animals; D000242:Cyclic AMP / Q000494:pharmacology*; D004789:Enzyme Activation; D006168:Guinea Pigs; D007700:Kinetics; D008274:Magnesium / Q000494:pharmacology; D008930:Mitochondria, Liver / Q000187:drug effects / Q000201:enzymology*; D011092:Polyethylene Glycols; D011494:Protein Kinases / Q000378:metabolism*; D051381:Rats; D013045:Species Specificity
chemical_list: D011092:Polyethylene Glycols; D000242:Cyclic AMP; D011494:Protein Kinases; D008274:Magnesium