Corpora amylacea in the peripheral nerve axons.
Deposits similar to corpora amylacea were observed by electron microscopy within myelinated axons in the peripheral nerves in a case of familial spastic paralysis. Ultrastructurally the deposits consisted of randomly interlacing short filaments which were closely related to glycogen granules present in the periphery of the deposits. A possible relationship between the filamentous structures and glycogen granules is discussed. The significance of this inclusion and of related bodies is also discussed.
D000328:Adult; D000682:Amyloid / Q000032:analysis; D001369:Axons / Q000648:ultrastructure*; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D006003:Glycogen / Q000032:analysis; D006801:Humans; D002479:Inclusion Bodies / Q000032:analysis / Q000648:ultrastructure*; D008297:Male; D009128:Muscle Spasticity / Q000473:pathology*; D009422:Nervous System Diseases / Q000473:pathology; D010525:Peripheral Nerves / Q000648:ultrastructure*
D000682:Amyloid; D006003:Glycogen