Mechanism of action of somatostatin: growth-hormone release [45Ca]calcium ion efflux and cyclic nucleotide metabolism of bovine anterior-pituitary slices in the presence of prostaglandin E2 and 1-methyl-3-isobutylxanthine.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002417:Cattle; D000242:Cyclic AMP / Q000378:metabolism*; D006152:Cyclic GMP / Q000378:metabolism*; D013006:Growth Hormone / Q000378:metabolism*; D066298:In Vitro Techniques; D007700:Kinetics; D010902:Pituitary Gland / Q000378:metabolism*; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000378:metabolism*; D011458:Prostaglandins E / Q000494:pharmacology*; D013004:Somatostatin / Q000494:pharmacology*; D014970:Xanthines / Q000494:pharmacology*
D011458:Prostaglandins E; D014970:Xanthines; D013004:Somatostatin; D013006:Growth Hormone; D000242:Cyclic AMP; D006152:Cyclic GMP; D002118:Calcium