The action of collagenase on K-type Bence-Jones proteins.
The proteolytic action of a bacterial collagenase on two Bence-Jones k chains has been studied and the localization of the cleavage sites accomplished. The implications of this enzymatic attack are discussed.
D000595:Amino Acid Sequence; D001536:Bence Jones Protein / Q000378:metabolism*; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism*; D007147:Immunoglobulin Light Chains / Q000378:metabolism*; D007145:Immunoglobulin kappa-Chains / Q000378:metabolism*; D003012:Microbial Collagenase / Q000378:metabolism*; D009194:Myeloma Proteins / Q000378:metabolism; D013379:Substrate Specificity
D007070:Immunoglobulin A; D007147:Immunoglobulin Light Chains; D007145:Immunoglobulin kappa-Chains; D009194:Myeloma Proteins; D001536:Bence Jones Protein; D003012:Microbial Collagenase