[Mechanism of action of catecholamines on sodium transport in sections of rat renal cortex].
Stimulation of renal beta-adrenoreceptors increased passive accumulation of sodium and water contents in cells of renal sections incubated in non-oxygenated medium without potassium and glucose but had no effect on the passive loss of potassiuna. During incibation of sodium loaded sections in oxygenated medium with potassium and glucose, stimulation of beta-adrenoreceptors increased excertion of sodium from the sections, and accumulation of potassium, which was followed by reducing of intracellular water. Activation of beta-adrenoreceptors during action of catecholamines seems to elicit an increased passive inflow of sodium into the cells of renal channels and to activate the ionic pump pumping away sodium in exchange for potassium.
D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D001693:Biological Transport, Active / Q000187:drug effects; D004347:Drug Interactions; D004837:Epinephrine / Q000494:pharmacology; D007545:Isoproterenol / Q000494:pharmacology; D007684:Kidney Tubules / Q000378:metabolism / Q000502:physiology*; D010646:Phentolamine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D012964:Sodium / Q000378:metabolism*; D014867:Water / Q000378:metabolism
D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D014867:Water; D012964:Sodium; D011433:Propranolol; D007545:Isoproterenol; D004837:Epinephrine; D010646:Phentolamine
Mekhanizm deĭstviia katekholaminov na transport natrii v srezakh kory pochek krys.