[Chronic hypophosphatemic osteopathy ("rachitis"). Clinico-osteological review].
Chronic hypophosphatemia is the most common type of "resistant" rickets. Bone deformities, dwarfism and X-chromosomal dominant heredity, are regular findings in this "inborn error" of phosphate metabolism. Continumous administration of high dosage of vitamin D results in some improvement of the rickets-like bone lesions. Oral administration of phosphate seems to improve longitudinal growth. A summary of our experiences in 44 patients is presented.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004392:Dwarfism / Q000209:etiology; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D007015:Hypophosphatemia, Familial / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D010710:Phosphates / Q000627:therapeutic use; D014807:Vitamin D / Q000627:therapeutic use
D010710:Phosphates; D014807:Vitamin D
Die chronische hypophosphatämische Osteopathie ("Rachitis"). Klinisch-osteologische Ubersicht.