RNase T1-resistant oligonucleotides of an N- and a B-tropic murine leukemia virus of BALB/c: evidence for recombination between these viruses.
We used two-dimensional gel electrophoresis to obtain fingerprints of 32P-labeled RNase T1-resistant oligonucleotides derived from the genomes of an N- and a B-tropic murine leukemia virus of BALB/c. These viruses share approximately 30 large T1-resistant oligonucleotides. In addition, there are eight large oligonucleotides unique to the N-tropic virus, and there are six B-trophic virus-specific oligonucleotides. Viruses, designated XLP-N, which appear by biological criteria and analysis of virion proteins to be recombinants between these N- and B-tropic viruses, possess some but not all of the N or B virus-specific oligonucleotides.
D004352:Drug Resistance, Microbial; D005814:Genes, Viral; D009052:Leukemia Virus, Murine / Q000032:analysis / Q000235:genetics*; D009843:Oligoribonucleotides / Q000032:analysis; D012367:RNA, Viral / Q000032:analysis*; D011995:Recombination, Genetic; D012260:Ribonucleases / Q000494:pharmacology
D009843:Oligoribonucleotides; D012367:RNA, Viral; D012260:Ribonucleases