[Polyadenylic acid rich RNA fractions in primary hepatomas induced with diethylnitrosamine].
The column chromatography with unmodified cellulose revealed a polyadenilic acid rich fraction of total RNA from diethylnitrosamine induced primary hepatomas and normal rat liver. It was shown that the quantity of this fraction was increased to 3.15 per cent. The 2.5% polyacrylamide gel electrophoresis of the polyadenylic acid rich fraction indicated its different spectra in tumors and normal rat liver, the main change being in bipolymer fractions with sedimentation coefficient 28 S and higher.
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000032:analysis* / Q000139:chemically induced; D055598:Chemical Phenomena; D002621:Chemistry; D004052:Diethylnitrosamine; D008113:Liver Neoplasms / Q000032:analysis* / Q000139:chemically induced; D008297:Male; D011061:Poly A; D012334:RNA, Neoplasm / Q000302:isolation & purification*; D051381:Rats
D012334:RNA, Neoplasm; D011061:Poly A; D004052:Diethylnitrosamine
Obogashchennye poliadenilovoĭ kislotoĭ fraktsiĭ RNK v pervichnykh gepatomakh indutsirovannykh diétilnitrozaminom