Treatment of metastases in nephroblastoma.
A series of 36 children with nephroblastoma treated between 1966 and 1973 was analysed. None of the patients with stages I or II and microscopic type I or II developed metastases; 5 of 7 patients with stages I or II and microscopic type III developed metastases. All patients in stage III developed metastases. Fifteen patients developed metastases after the termination of the primary treatment. Of 9 patients with pulmonary metastases only, 6 are free of disease, all patients with metastases in other sites are dead.
D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D008113:Liver Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D008175:Lung Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D008297:Male; D009362:Neoplasm Metastasis; D009396:Wilms Tumor / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy*