Adenosine 3',5'-cyclic monophosphate and guanosine 3',5'-cyclic monophosphate levels in human breast cancer tissue.
Intracellular levels of adenosine 3',5'-cyclic monophosphate and guanosine 3',5'-cyclic monophosphate were measured in breast carcinomas. These levels were increased significantly as compared to normal breast tissues. In benign breast tumors, intermediate levels of adenosine 3'5'-cyclic monophosphate were observed, but they did not differ significantly with malignant tissues. No relation has been shown with estradiol or progesterone binding sites.
D001943:Breast Neoplasms / Q000378:metabolism*; D000242:Cyclic AMP / Q000378:metabolism*; D006152:Cyclic GMP / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism; D005260:Female; D006801:Humans; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D004958:Estradiol; D000242:Cyclic AMP; D006152:Cyclic GMP