title: Subcellular distribution of the tumor-specific transplantation antigen of simian virus 40-transformed cells.
abstract: TU-5, a simian virus 40 (SV40)-transformed cell line of BALB/c origin, expressed the SV40-specific T-antigen and a transplantation  antigen (TSTA). Nuclei and plasma membranes were prepared from these cells and shown on the basis of the distribution of T-antigen and histocompatibility (H-2) antigens to be relatively free of cross contamination. Most of the TSTA, estimated by tumor rejection, was associated with the nuclear fraction.
mesh_terms: D000818:Animals; D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D002458:Cell Fractionation; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology; D002467:Cell Nucleus / Q000276:immunology; D002471:Cell Transformation, Neoplastic; D006649:Histocompatibility Antigens; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D013539:Simian virus 40 / Q000276:immunology*; D014185:Transplantation, Isogeneic; D014412:Tumor Virus Infections / Q000276:immunology*
chemical_list: D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D006649:Histocompatibility Antigens