Comparison of toxicity and mutagenicity of butyl methanesulfonate among human lymphoblast lines.
The toxic and mutagenic effects of butyl methanesulfonate (BMS) were compared among four diploid human lymphoblast lines, MIT-2, WI-L2, MGL8B-2 and GM 130. The toxic and mutagenic effects of 24-h exposure to BMS were similar for the MIT-2, WI-L2 and MGL8B-2 lines, while the GM 130 line was strikingly resistant to the toxic and mutagenic effects of BMS.
D000440:Butanols / Q000494:pharmacology / Q000633:toxicity*; D002460:Cell Line; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects; D008698:Mesylates / Q000494:pharmacology / Q000633:toxicity*; D009153:Mutagens
D000440:Butanols; D008698:Mesylates; D009153:Mutagens