[Role of the medial hypothalamus in regulating the pituitary-adrenocortical system].
In unrestrained rabbits, inhibition of ACTH release as determined by changes in plasma levels of corticosteroids, followed electrolytic lesion of the dorso-and ventromedia nuclei of the hypothalamus. Electric stimulation of the dorsal midbrain tegmentum had activated ACTH prior to lesion; after the lesion of the dorso-and ventromedial nuclei the stimulation produced no response. The dorso-and ventromedial nuclei of the hypothalamus are essential for basal and induced secretion of the ACTH.
D000305:Adrenal Cortex Hormones / Q000378:metabolism*; D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000818:Animals; D001931:Brain Mapping; D004558:Electric Stimulation; D007031:Hypothalamus / Q000502:physiology*; D007033:Hypothalamus, Middle / Q000502:physiology*; D008297:Male; D010913:Pituitary-Adrenal System / Q000502:physiology*; D011817:Rabbits; D013681:Tegmentum Mesencephali / Q000502:physiology
D000305:Adrenal Cortex Hormones; D000324:Adrenocorticotropic Hormone
Rol'medial'nogo gipotalamusa v reguliatsii gipofizarno-adrenokortikal'noĭ sistemy.