[Pathologic anatomy of experimental diseases of small laboratory animals caused by encephalomyocarditis virus (strain EMK-70)].
The results of pathomorphological investigation of the disease in small laboratory animals experimentally induced by the EMC-70 strain of encephalomyocarditis virus isolated from monkeys are presented. Irrespective of the mode of virus injection, the newborn and juvenile mice developed some lesions in the brown fat, transverse-striated muscles, as well as in the brain and heart. In guinea pigs the changes were characterized by the development of severe myocarditis and encephalitis accompanied by viral antigen accumulation. The disease induced by the EMC-70 strain could not be differentiated from the Coxsackie infection by the pathomorphological data. This fact should be taken into consideration in solving some problems pertinent to pathoanatomical diagnosis of viral diseases.
D002001:Adipose Tissue, Brown / Q000473:pathology; D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000473:pathology; D004686:Encephalomyocarditis virus; D004769:Enterovirus Infections / Q000473:pathology*; D006168:Guinea Pigs; D008099:Liver / Q000473:pathology; D051379:Mice; D009132:Muscles / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D011817:Rabbits; D013045:Species Specificity
Patologicheskaia anatomiia éksperimental'nogo zabolevaniia melkikh laboratornykh zhivotnykh, vyzvannogo virusom éntsefalomiokardita (shtamm EMK-70).