Immunoelectrophoretic investigations on Sendai virus envelope antigens in relation to host antigens.
The different antigenic fractions characteristic of egg-cultivated Sendai virus envelopes were studied by immunoelectrophoresis. Virus-specific and host-specific fractions were identified. It was proved that incorporation of the host membrane fragments into the viral envelopes is not a passive phenomenon. During the last stages of its assembly and release, the virus incorporates into the envelopes some host glycoproteins, after an active biochemical processing resulting in a considerable reduction of their molecular weight, while the host antigenic determinants remain almost unaltered.
D000818:Animals; D000941:Antigens / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis*; D002462:Cell Membrane / Q000276:immunology; D002642:Chick Embryo; D005321:Extraembryonic Membranes; D010222:Parainfluenza Virus 1, Human / Q000276:immunology*; D014776:Virus Cultivation
D000941:Antigens; D000956:Antigens, Viral