title: [Action of distension upon uterine growth (author's transl)].
abstract: The uterine horn growth has been studied in castrated female rats under the influence of distension. One of the two horns was used as a control horn, to insure us that no endogenous hormone was responsible for the uterine growth. Morphological studies, as well at low as at high resolution, demonstrated the ability of distension to initiate an epithelial growth. The use of 3H thymidine, or H3 uridine also provided some evidence for RNA synthesis 30 mm after distension initiation, and DNA synthesis 24 to 48 hours after distension onset. In these cases all the uterine tissues were concerned.
mesh_terms: D000818:Animals; D002369:Castration; D002455:Cell Division / Q000187:drug effects; D000242:Cyclic AMP / Q000378:metabolism; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D008854:Microscopy, Electron; D010812:Physical Stimulation; D051381:Rats; D013806:Theophylline / Q000494:pharmacology; D013936:Thymidine / Q000378:metabolism; D014529:Uridine / Q000378:metabolism; D014599:Uterus / Q000033:anatomy & histology / Q000254:growth & development* / Q000378:metabolism
chemical_list: D013806:Theophylline; D000242:Cyclic AMP; D013936:Thymidine; D014529:Uridine
vernacular_title: Action de la distension sur la croissance utérine