[Immunocytochemical localization of neurons containing ACTH 17-39 in the rat brain].
Immunoreactive neurons and fibers were localized in the Rat brain by immunocytochemistry using an anti-ACTH 17-39 antiserum. Neither adrenalectomy nor water deprivation affected intensity of distribution of reaction of labelled neurons whereas colchicine increased labelling of hypothalamic perikarya. These results support the neuronal origin of cerebral ACTH.
D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000032:analysis* / Q000502:physiology; D000818:Animals; D001921:Brain / Q000166:cytology*; D001923:Brain Chemistry; D003078:Colchicine / Q000494:pharmacology; D004032:Diet; D005260:Female; D007031:Hypothalamus / Q000187:drug effects; D007124:Immunoenzyme Techniques; D008297:Male; D009412:Nerve Fibers / Q000032:analysis; D009474:Neurons / Q000032:analysis* / Q000378:metabolism; D051381:Rats; D014867:Water
D014867:Water; D000324:Adrenocorticotropic Hormone; D003078:Colchicine
Identification immunocytochimique de neurones contenant de l'ACTH 17-39 dans le cerveau du rat.