Adrenergic regulation of phosphorolysis and hydrolysis of glycogen in smooth muscle of rabbit stomach in situ.
In smooth muscle of rabbit stomachs, activities of hydrolytic and phosphorolytic enzymes of glycogen degradation under the influence of agents stimulating and blocking adrenergic alpha and beta-receptors were studied. The results indicate that beta-adrenergic receptor in smooth muscle activated not only phosphorolytic, but also hydrolytic degradation of glycogen, and the alpha-adrenergic receptor only inhibited phosphorolysis but had no influence on hydrolysis of glycogen.
D000109:Acetylcholine / Q000494:pharmacology; D000681:Amylases / Q000378:metabolism; D000818:Animals; D001626:Bethanechol Compounds / Q000494:pharmacology; D000242:Cyclic AMP / Q000494:pharmacology; D006003:Glycogen / Q000378:metabolism*; D006600:Hexosephosphates / Q000378:metabolism; D008297:Male; D009130:Muscle, Smooth / Q000378:metabolism*; D011817:Rabbits; D013015:Sotalol / Q000494:pharmacology; D013566:Sympathomimetics / Q000494:pharmacology
D001626:Bethanechol Compounds; D006600:Hexosephosphates; D013566:Sympathomimetics; D006003:Glycogen; D013015:Sotalol; D000242:Cyclic AMP; D000681:Amylases; D000109:Acetylcholine