Mitogen-induced activation of stable E-rosettes by human lymphocytes.
Following on an earlier study which demonstrated that PHA can activate human lymphocytes to form temperature-stable (37 degrees C.) E-rosettes with sheep red blood cells, a number of other mitogens were tested. These included Concanavalin A, pokeweed mitogen, soybean agglutinin, sodium periodate, and galactose oxidase. All except soybean agglutinin demonstrated the capability to activate lymphocytes to form stable E-rosettes.
D003208:Concanavalin A / Q000494:pharmacology; D005692:Galactose Oxidase / Q000494:pharmacology; D006801:Humans; D037102:Lectins; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D008934:Mitogens / Q000494:pharmacology*; D010504:Periodic Acid / Q000494:pharmacology; D010835:Phytohemagglutinins / Q000494:pharmacology; D037121:Plant Lectins; D011043:Pokeweed Mitogens / Q000494:pharmacology; D012397:Rosette Formation; D013025:Glycine max
D037102:Lectins; D008934:Mitogens; D010835:Phytohemagglutinins; D037121:Plant Lectins; D011043:Pokeweed Mitogens; D010504:Periodic Acid; D003208:Concanavalin A; D005692:Galactose Oxidase