Sterol balance in a patient with abetalipoproteinaemia.
Total-body cholesterol synthesis was measured in a woman with abetalipoproteinaemia and in a normal woman of similar age. The rate of synthesis of cholesterol was 15.4 +/- 4.1 mg/kg/day in the patient and 14.3 +/- 2.6 mg/kg/day in the control subject, indicating that cholesterol synthesis in the whole body is not increased in the complete absence of plasma low density lipoprotein.
D000012:Abetalipoproteinemia / Q000097:blood / Q000378:metabolism*; D000328:Adult; D001647:Bile Acids and Salts / Q000032:analysis; D002784:Cholesterol / Q000096:biosynthesis*; D002791:Cholesterol, Dietary / Q000032:analysis; D005243:Feces / Q000032:analysis; D005260:Female; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood
D001647:Bile Acids and Salts; D002791:Cholesterol, Dietary; D008077:Lipoproteins, LDL; D002784:Cholesterol