Adverse effects of electrical energy applied to the nervous system.
Neural prostheses activated by radiofrequency transmission are currently being implanted to treat a variety of clinical problems. It is essential that neither the materials used in these prostheses, particularly the electrodes, nor the stimulus parameters that are employed will cause neural damage. The experiences of investigators engaged in both the experimental laboratory and clinical studies of the effects of electrical stimulation are reported herein.
D000818:Animals; D001812:Blood-Brain Barrier; D002493:Central Nervous System Diseases / Q000209:etiology; D002531:Cerebellum / Q000378:metabolism; D002540:Cerebral Cortex; D002561:Cerebrovascular Disorders / Q000209:etiology; D004599:Electric Stimulation Therapy / Q000009:adverse effects*; D004567:Electrodes, Implanted; D006801:Humans; D009422:Nervous System Diseases / Q000209:etiology*; D010148:Intractable Pain / Q000628:therapy; D010523:Peripheral Nervous System Diseases / Q000209:etiology; D010791:Phrenic Nerve; D010841:Pia Mater / Q000098:blood supply; D012640:Seizures / Q000209:etiology; D013118:Spinal Cord Diseases / Q000209:etiology