Apolipoprotein A-1 in cholestatic liver diseases.
The apolipoprotein A-1 in cholestatic liver diseases was determined by rocket immunoelectrophoresis. A decrease in the serum apo A-1 was generally observed in LP-X positive liver disease, particularly in the patients with extrahepatic biliary obstruction. With reference to LP-X levels and LCAT activity, the results indicated that not only hepatocellular damage but also cholestasis contribute to the decrease of apo A-1 concentration in patients with liver disease.
D000328:Adult; D001053:Apolipoproteins / Q000097:blood*; D002779:Cholestasis / Q000097:blood*; D005260:Female; D006801:Humans; D007122:Immunoelectrophoresis / Q000379:methods; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D007862:Phosphatidylcholine-Sterol O-Acyltransferase / Q000097:blood
D001053:Apolipoproteins; D008077:Lipoproteins, LDL; D007862:Phosphatidylcholine-Sterol O-Acyltransferase