title: Cytochrome c oxidase as the receptor molecule for chemoaccumulation (chemotaxis) of Euglena toward oxygen.
abstract: Chemoaccumulation of Euglena gracilis toward oxygen was selectively inhibited, without concomitant effects on cell motility, by cyanide (10(-6) to 10(-4) molar) and carbon monoxide (5 x 10(-5) to 5 x 10(-4) molar). Above these concentrations, motility of the cell was imparied and the chemosensory response was inhibited. Azide did not affect chemoaccumulation even at 5 x 10(-3) molar. It is concluded that cytochrome a3 serves as the chemoreceptor molecule for oxygen-mediated behavioral responses in Euglena.
mesh_terms: D000818:Animals; D001386:Azides / Q000494:pharmacology; D002248:Carbon Monoxide / Q000494:pharmacology; D002633:Chemotaxis / Q000187:drug effects; D003486:Cyanides / Q000494:pharmacology; D003580:Cytochromes / Q000037:antagonists & inhibitors; D003576:Electron Transport Complex IV / Q000037:antagonists & inhibitors / Q000502:physiology*; D005056:Euglena gracilis / Q000502:physiology*; D010100:Oxygen; D011955:Receptors, Drug / Q000502:physiology
chemical_list: D001386:Azides; D003486:Cyanides; D003580:Cytochromes; D011955:Receptors, Drug; D002248:Carbon Monoxide; D003576:Electron Transport Complex IV; D010100:Oxygen