Myeloperoxidase-Cl--H2O2 bactericidal system: effect of bacterial membrane structure and growth conditions.
The human-myeloperoxidase-Cl--H2O2 bactericidal system killed (i) smooth Enterobacteria spp. greater than or equal to rough and (ii) static-grown, stationary-phase bacteria greater than or equal to aerated-grown, log-phase. This is in contrast to human neutrophil granule extracts (involved in nonoxidative bactericidal mechanisms) that kill rough and aerated log-phase Enterobacteria spp. much more efficiently.
D001433:Bacteriolysis; D002462:Cell Membrane / Q000648:ultrastructure; D002712:Chlorides / Q000378:metabolism; D004926:Escherichia coli / Q000254:growth & development / Q000648:ultrastructure; D006861:Hydrogen Peroxide / Q000378:metabolism; D009504:Neutrophils / Q000502:physiology; D009195:Peroxidase / Q000378:metabolism*; D010544:Peroxidases / Q000378:metabolism*; D012475:Salmonella / Q000254:growth & development / Q000648:ultrastructure
D002712:Chlorides; D006861:Hydrogen Peroxide; D010544:Peroxidases; D009195:Peroxidase