[Possible role of free radicals in the transformations and mechanism of physiological action of vitamin D].
Deficiency of vitamine D is accompanied with a decrease of ESR signal intensity from g = 2.003, as well as of the signals with g = 1.94 and gav. = 2.25 in the liver and kidneys of young rats. Injection of 2.5 g ergocalciferole (vitamine D2) to these animals results in a complete or partial normalization of the intensity of these signals during 6--16 hrs and an increase of the ESR signal intensity from g = 2.003 in small intestine mucosa.
D000818:Animals; D004578:Electron Spin Resonance Spectroscopy; D004872:Ergocalciferols / Q000627:therapeutic use; D005609:Free Radicals; D007421:Intestine, Small / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008297:Male; D051381:Rats; D014808:Vitamin D Deficiency / Q000188:drug therapy / Q000378:metabolism*
D004872:Ergocalciferols; D005609:Free Radicals
O vozmozhnoĭ roli svobodnykh radikalov v prevrashcheniiakh i mekhanizme fiziologicheskogo deĭstviia vitamina D