3-Deazaadenosine, an inhibitor of adenosylhomocysteine hydrolase, inhibits reproduction of Rous sarcoma virus and transformation of chick embryo cells.
D000241:Adenosine / Q000494:pharmacology; D000818:Animals; D001354:Avian Leukosis Virus / Q000254:growth & development; D001358:Avian Sarcoma Viruses / Q000187:drug effects*; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D002472:Cell Transformation, Viral / Q000187:drug effects*; D002642:Chick Embryo; D046508:Culture Techniques; D003839:Deoxyadenosines / Q000494:pharmacology; D005947:Glucose / Q000378:metabolism; D006867:Hydrolases / Q000037:antagonists & inhibitors; D007536:Isomerism; D012263:Ribonucleosides / Q000494:pharmacology*; D014372:Tubercidin / Q000494:pharmacology*; D014779:Virus Replication / Q000187:drug effects*
D003839:Deoxyadenosines; D012263:Ribonucleosides; D006867:Hydrolases; D005947:Glucose; D000241:Adenosine; D014372:Tubercidin