The EM immunocytochemical demonstration of lysozyme in macrophage giant cells in sarcoidosis.
The giant cells (multinucleate macrophages) of human sarcoidosis have been shown by the unlabelled antibody immunoperoxidase technique at electron microscope level to contain lysozyme within cytoplasmic granules.
D006801:Humans; D007124:Immunoenzyme Techniques; D002479:Inclusion Bodies / Q000201:enzymology / Q000648:ultrastructure; D008264:Macrophages / Q000201:enzymology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009113:Muramidase / Q000032:analysis*; D012507:Sarcoidosis / Q000201:enzymology*
D009113:Muramidase