Biochemical studies of pigments from a pathogenic fungus Microsporum cookei. V. Evidence for the transmembrane permeability of xanthomegnin across phospholipid bilayer membranes.
Direct evidence is provided for the transmembrane permeation of xanthomegnin across phospholipid bilayer membranes using ascorbate-loaded liposomes. This process may be associated with an uncoupling effect on the oxidative phosphorylation of mitochondria.
D002463:Cell Membrane Permeability; D003574:Cytochrome c Group / Q000378:metabolism; D008081:Liposomes; D008864:Microsporum; D008928:Mitochondria / Q000378:metabolism; D010085:Oxidative Phosphorylation; D010860:Pigments, Biological / Q000378:metabolism* / Q000494:pharmacology; D014475:Uncoupling Agents
D003574:Cytochrome c Group; D008081:Liposomes; D010860:Pigments, Biological; D014475:Uncoupling Agents