A unifying mechanism for stimulation of mammalian pyruvate dehydrogenase(a) kinase by reduced nicotinamide adenine dinucleotide, dihydrolipoamide, acetyl coenzyme A, or pyruvate.
D000105:Acetyl Coenzyme A / Q000494:pharmacology*; D000818:Animals; D002417:Cattle; D004229:Dithiothreitol / Q000494:pharmacology; D007668:Kidney / Q000201:enzymology; D007700:Kinetics; D008928:Mitochondria / Q000201:enzymology; D008930:Mitochondria, Liver / Q000201:enzymology; D009243:NAD / Q000494:pharmacology*; D009994:Osmolar Concentration; D011494:Protein Kinases / Q000378:metabolism*; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism; D011773:Pyruvates / Q000494:pharmacology*; D008063:Thioctic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology
D011768:Pyruvate Dehydrogenase Complex; D011773:Pyruvates; D009243:NAD; D000105:Acetyl Coenzyme A; D008063:Thioctic Acid; D011494:Protein Kinases; D004229:Dithiothreitol