Evidence against involvement of endorphins in sexual arousal and orgasm in man.
In a double-blind study, intravenous injection of naloxone, at a dose sufficient to saturate the opiate (endorphin) receptors, had no effect on sexual arousal, penile erection, ejaculation, or orgasm in a human subject. Apparently, endorphins are not involved in these phenomena.
D000328:Adult; D004311:Double-Blind Method; D004723:Endorphins / Q000502:physiology*; D006801:Humans; D007989:Libido / Q000502:physiology*; D008297:Male; D009270:Naloxone / Q000494:pharmacology; D009948:Orgasm / Q000502:physiology*; D011957:Receptors, Opioid / Q000187:drug effects; D012647:Self-Assessment
D004723:Endorphins; D011957:Receptors, Opioid; D009270:Naloxone