Origin of polyoma virus-associated endonuclease.
Polyoma virus particles purified from infected cells, but not from the culture medium, exhibited an endonuclease activity distinct from the serum contaminant recently described. This endonuclease cleaved form I polyoma DNA once only per molecule, at one of three possible sites corresponding to the known adenosine-ribosylthymine-rich regions of the molecule.
D002460:Cell Line; D004270:DNA, Circular / Q000378:metabolism; D004279:DNA, Viral / Q000378:metabolism; D003851:Deoxyribonucleases / Q000378:metabolism; D004720:Endonucleases / Q000378:metabolism; D011120:Polyomavirus / Q000201:enzymology
D004270:DNA, Circular; D004279:DNA, Viral; D003851:Deoxyribonucleases; D004720:Endonucleases