title: [Reverse electron transfer from the cytochrome c level in cyanide-resistant mitochondria of the yeast, Candida lipolytica].
abstract: The ability of cyanide-resistant mitochondria of yeast Candida lipolytica to perform reverse electron transfer from cytochrome c to alternative oxidase was studied. It was shown that the energy for such a transfer can be provided by high energy intermediates or membrane potential but not by ATP. Reverse electron transfer from cytochrome c is impossible due to energy of NADH and alpha-glycerophosphate oxidation via alternative pathway in the presence of cyanide. These results prove once again that electron transfer via alternative pathway is not connected with the energy accumulation.
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D002175:Candida / Q000378:metabolism*; D003486:Cyanides / Q000494:pharmacology*; D003574:Cytochrome c Group / Q000378:metabolism*; D004352:Drug Resistance, Microbial; D004579:Electron Transport / Q000187:drug effects; D004734:Energy Metabolism; D005994:Glycerophosphates / Q000378:metabolism; D008564:Membrane Potentials; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D009243:NAD / Q000378:metabolism
chemical_list: D003486:Cyanides; D003574:Cytochrome c Group; D005994:Glycerophosphates; D009243:NAD; D000255:Adenosine Triphosphate
vernacular_title: Obratnyĭ perenos elektronov na urovne tsitokhroma c v tsianidrezistentnykh mitokhondriiakh drozhzheĭ Candida lypolytica.