title: Collaborative complementation study of temperature-sensitive mutants of herpes simplex virus types 1 and 2.
abstract: Twenty-three complementation groups of herpes simplex virus type 1 (HSV-1) and 20 of HSV-2 were identified by qualitative and quantitative complementation analysis from among 43 temperature-sensitive (ts) mutants of HSV-1 and 29 ts mutants of HSV-2 which had been isolated independently in 10 laboratories.
mesh_terms: D005814:Genes, Viral; D005816:Genetic Complementation Test / Q000379:methods; D009154:Mutation; D018139:Simplexvirus / Q000235:genetics* / Q000254:growth & development; D013696:Temperature; D014779:Virus Replication