Restriction to the cell nucleus of virus-induced host RNA's in a rat kidney tumor induced by polyoma virus.
RNA transcripts of repetitive DNA of WF rat kidney, which were derepressed during transformation by polyoma virus, were not transported to the cytoplasm in the tumor cells. Transcripts of repetitive DNA found in the normal cell nucleus were all transported to the cytoplasm in the tumor cells, including those restricted to the nuclei in the normal cells.
D000818:Animals; D001692:Biological Transport; D002467:Cell Nucleus / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D007680:Kidney Neoplasms / Q000209:etiology / Q000378:metabolism*; D009374:Neoplasms, Experimental / Q000209:etiology / Q000378:metabolism; D011120:Polyomavirus; D012313:RNA / Q000378:metabolism*; D012334:RNA, Neoplasm / Q000378:metabolism; D051381:Rats; D011920:Rats, Inbred WF; D014412:Tumor Virus Infections / Q000378:metabolism
D012334:RNA, Neoplasm; D012313:RNA