Immunoglobulin synthesis by an SV-40-induced hamster lymphoma.
A transplantable lymphoid tumour induced in Syrian hamsters by SV-40 was shown to synthesize a 7Sgamma2 monoclonal immunoglobulin of the same idiotype was also found in the membrane of the tumour cell. The induction of immunoglobulin synthesizing tumours by SV-40 should be useful for studies on immunoglobulin synthesis, lymphoid cell receptors and tumour immunity.
D000818:Animals; D002462:Cell Membrane / Q000276:immunology; D006224:Cricetinae; D005779:Immunodiffusion; D007136:Immunoglobulins / Q000096:biosynthesis*; D008223:Lymphoma / Q000276:immunology*; D009374:Neoplasms, Experimental / Q000276:immunology; D013539:Simian virus 40
D007136:Immunoglobulins