title: [Hexokinase activity in blood serum during carcinogenesis].
abstract: During carcinogenesis, induced by diethylnitrosamine in rats Wistar (in doses of 2.5 mg per Kg of weight daily with drinking water), the hexokinase (HK) activity in blood serum was observed with the appearance of the first morphological symptoms of tumor growth. It is observed mainly starting from the first months. At the end of the experimental period (8-9th month), when hepatomas develop in the liver, the HK activity in blood serum was noted almost in all cases. No serum HK activity was found in control rats.
mesh_terms: D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000201:enzymology*; D006593:Hexokinase / Q000097:blood*; D008113:Liver Neoplasms / Q000201:enzymology*; D008297:Male; D009374:Neoplasms, Experimental / Q000201:enzymology; D051381:Rats
chemical_list: D006593:Hexokinase
vernacular_title: Ob aktivnosti geksokinazy v syrovotke krovi pri kantserogeneze