Differences between murine C1300 neuroblastoma clones detected by rosette formation with nerve growth factor-coated sheep red blood cells.
The expression of receptors for nerve growth factor (NGF) on the cell surface was assayed by rosette formation with ligand-coated sheep red blood cells (SRBC). Cell clones derived from the murine C1300 neuroblastoma and from hybrids between a neuroblastoma clone and L cell clones showed a wide variation in the capacity to form rosettes with NGF-coated SRBC. All the neuroblastoma, L cell and hybrid clones formed rosettes with phytohemagglutinin-coated SRBC and none formed rosettes with cytochrome c- or ferritin-coated SRBC or with SRBC not coated with ligand.
D000818:Animals; D001665:Binding Sites; D002999:Clone Cells; D003574:Cytochrome c Group / Q000378:metabolism; D005293:Ferritins / Q000378:metabolism; D006822:Hybrid Cells; D007158:Immunologic Techniques; D007739:L Cells; D037102:Lectins / Q000378:metabolism; D051379:Mice; D009414:Nerve Growth Factors / Q000378:metabolism*; D009447:Neuroblastoma / Q000378:metabolism*
D003574:Cytochrome c Group; D037102:Lectins; D009414:Nerve Growth Factors; D005293:Ferritins