Application of counterimmunoelectrophoresis in rapid detection of cytomegalovirus antibodies.
Determination of cytomegalovirus antibodies by counterimmune-electrophoresis correlated well with results of complement-fixation antibody studies. The sensitivity and specificity of the counterimmunoelectrophoresis method (vs. complement fixation) was 88.9%. Fourfold antibody increases detected by complement fixation were also detected by counterimmunoelectrophoresis. In addition, no cross-reaction was observed in the counterimmunoelectrophoresis assay between other DNA viral antisera and cytomegalovirus antigen (Ad-169).
D000914:Antibodies, Viral / Q000032:analysis*; D003168:Complement Fixation Tests; D003378:Counterimmunoelectrophoresis / Q000379:methods*; D003429:Cross Reactions; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D007122:Immunoelectrophoresis / Q000379:methods*; D016030:Kidney Transplantation; D011183:Postoperative Complications / Q000175:diagnosis; D014184:Transplantation, Homologous
D000914:Antibodies, Viral