Presence of Epstein-Barr virus receptors, but absence of virus penetration, in cells of an Epstein-Barr virus genome-negative human lymphoblastoid T line (Molt 4).
This paper reports a unique type of interaction of Epstein-Barr virus (EBV) with an EBV receptor-positive, genome-negative human lymphoid T cell line (Molt 4), which can be summarized as follows. Although Molt 4 cells express receptors for EBV, they appear to block the penetration of this virus. These observations are derived from combined studies with immunofluorescence and electron microscopy. It is possible that T cell lines bearing receptors for EBV may express such a control on virus penetration.
D000327:Adsorption; D001665:Binding Sites; D002051:Burkitt Lymphoma; D002460:Cell Line; D002462:Cell Membrane / Q000382:microbiology; D005455:Fluorescent Antibody Technique; D004854:Herpesvirus 4, Human / Q000254:growth & development*; D013601:T-Lymphocytes; D014779:Virus Replication