Search for disease-related cytotoxicity in mammary tumor patients.
Blood lymphocytes from benign and malignant mammary tumor patients ahd healthy blood donors were tested for cytotoxicity against monolayer cell lines, including two which were derived from breast carcinomas. Generally, the T subset was not cytotoxic, and if so this was not restricted to the relevant cell lines. In accordance with previous results 'null' cells were most efficient in the seemingly non-selective cytotoxicity.
D000232:Adenofibroma / Q000276:immunology; D001943:Breast Neoplasms / Q000276:immunology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000276:immunology; D002460:Cell Line; D003602:Cytotoxicity, Immunologic; D005260:Female; D006801:Humans; D007113:Immunity, Innate; D007141:Immunoglobulin Fc Fragments; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000276:immunology*; D009374:Neoplasms, Experimental / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D007141:Immunoglobulin Fc Fragments