title: The relationship of phosphodiesterase and cyclic AMP to the process of fluid secretion in the salivary glands of the ixodid tick Amblyomma americanum.
abstract: Phosphodiesterase (PDE) activity in the salivary glands of the female. Amblyomma americanum decreased as the tick progressed from a slow to a rapid phase of feeding, while the rate of fluid secretion increased when glands were stimulated with cyclic AMP and theophylline. Dopamine stimulated PDE activity and an 'inhibitory' factor was found in glands obtained from rapidly engorging ticks which decreased PDE activity. These findings are discussed as they relate to the process of fluid secretion by salivary glands of feeding ixodid ticks.
mesh_terms: D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D004435:Eating; D005260:Female; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism*; D012469:Salivary Glands / Q000378:metabolism*; D012636:Secretory Rate; D013987:Ticks / Q000502:physiology*
chemical_list: D000242:Cyclic AMP; D010727:Phosphoric Diester Hydrolases