[Results of concentrated irridiation in glioblastomas, astrocytomas and brain tumours of the adult (author's transl)].
Concentrated irradiation (two series of 1,800 rads in 2 sessions and 3 days) separated by a rest period of 3 to 4 weeks has been used to treat 214 adult patients with brain tumors between 1965 and 1972. These included 108 glioblastomas, 18 astrocytomas and 88 brain metastases from different origins. Early side effects are moderate or inexistent provided synthetic ACTH or corticoid steroids have been given several days before irradiation. Survival is related, at least, in the first 2 groups of primary tumor to local failure. For brain metastases, death could be related to others reasons. In spite of the fact that comparison is made with a previous series of 121 cases it seems that this type of irradiation gives the same survival rates. Moreover it has specific advantages as reducing duration of hospitalization and the number of treatment sessions.
D000328:Adult; D001932:Brain Neoplasms / Q000532:radiotherapy*; D005909:Glioblastoma / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D008722:Methods; D009362:Neoplasm Metastasis; D011836:Radiation Tolerance; D011879:Radiotherapy Dosage
Résultats de l'irradiation concentrée dans les glioblastomes, les astrocytomes malins et les métastases cérébrales de l'adulte