title: Lymphoid changes suggesting escalation of immune response into malignant lymphoma.
abstract: The conditions in which the microscopic changes of the lymphoid organs, especially lymph nodes, render difficult the histologic decision of immune response or malignant lymphoma, are reviewed. The possibility that in certain circumstances, prolonged, pathologic immune response escalate to malignant lymphomas, as well as the new classifications of these diseases, in terms of this conception are discussed.
mesh_terms: D003937:Diagnosis, Differential; D018219:Histiocytoma, Benign Fibrous / Q000276:immunology; D006801:Humans; D008199:Lymphadenitis / Q000276:immunology; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000276:immunology*; D008223:Lymphoma / Q000175:diagnosis / Q000276:immunology*; D014777:Virus Diseases / Q000276:immunology