[Burkitt's lymphoma].
The Burkitt's tumor is a neoplastic disease which occurs mostly in the tropics. Sporadic cases however are distributed all over the world. This undifferentiated lymphosarcoma predominates in children. Extralymphnodal in origin, quick growth and lack of pain are very characteristic signs. Unattended most of the patients die within a few months. Cytostatic treatment in connection with x-ray therapy and surgical proceedings show some results. The Epstein-Barr-virus is incriminated to play a causative role in the pathogenesis of Burkitt's lymphoma. But the experimental proof of its oncogenic activity in human beings has not yet been demonstrated. The problem of an active immunization is to be controlled.
D000349:Africa; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001859:Bone Neoplasms / Q000473:pathology; D002051:Burkitt Lymphoma / Q000532:radiotherapy; D002648:Child; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005153:Facial Neoplasms / Q000473:pathology; D005260:Female; D004854:Herpesvirus 4, Human / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D008297:Male; D009461:Neurologic Manifestations; D009915:Orbit / Q000601:surgery; D011323:Primates; D014611:Vaccination
D000914:Antibodies, Viral; D003520:Cyclophosphamide
Burkitt-Tumor