Alexia without agraphia, hemianopia, or color-naming defect: a disconnection syndrome.
A patient with alexia without agraphia, hemianopia, or color-naming defect was found at operation to have a meningioma arising from the tentorium cerebelli that compressed the inferior aspect of the left temporal-occipital junction. It is presumed to have involved only the left ventral visual association cortex and its inferior outflow tracts to the angular gyrus. The input from the right occipital area also was disconnected from the visual language verbal association area by involvement of the ventral outflow of the splenium of the corpus callosum. Preservation of color naming and matching suggests that these functions are dependent on the integrity of more dorsal occipital association systems.
D001932:Brain Neoplasms / Q000150:complications* / Q000503:physiopathology; D004411:Dyslexia, Acquired / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008579:Meningioma / Q000150:complications* / Q000503:physiopathology; D008875:Middle Aged; D009435:Synaptic Transmission