title: [Antiviral properties of analogs of distamycin A].
abstract: The effect of 9 analogues of distamycin A was studied in a tissue culture with respect to the virus of a smallpox vaccine and classical avian plague. Three analogues of distamycin A (I, VI, VII) were studied in chick embryos with respect to the smallpox and influenza viruses. The analogues were characterized by a loss or decrease of the activity against the smallpox vaccine virus as compared to distamycin A. In contrast to distamycin A analogue VII had an inhibitory effect on influenza infection in chick embryos.
mesh_terms: D000998:Antiviral Agents; D004214:Distamycins / Q000494:pharmacology*; D009980:Influenza A virus / Q000187:drug effects*; D009975:Orthomyxoviridae / Q000187:drug effects*; D011758:Pyrroles / Q000494:pharmacology*; D012901:Variola virus / Q000187:drug effects*
chemical_list: D000998:Antiviral Agents; D004214:Distamycins; D011758:Pyrroles
vernacular_title: Izuchenie protivovirusnykh svoĭstv analogov distamitsina A.