The use of a simple barrier system to exclude murine pathogens.
A simple barrier system was used successfully to exclude Mycoplasma pulmonis and Sendai virus from a conventional mouse room. 49 weeks after introduction of the barrier system of management Pasteurella pneumotropica was first isolated from animals in the room.
D000818:Animals; D005856:Germ-Free Life; D006799:Housing, Animal; D051379:Mice; D009174:Mycoplasma / Q000302:isolation & purification; D010222:Parainfluenza Virus 1, Human / Q000302:isolation & purification; D010325:Pasteurella / Q000302:isolation & purification; D013047:Specific Pathogen-Free Organisms; D014691:Ventilation