title: [HCO3- -stimulated ATPase of rat kidneys].
abstract: In homogenate and mitochondria of cortex and medulla of rat kidney a stimulating effect of different concentrations of bicarbonate on the ATPase activity was studied. By the rate of inhibition of Mg2+-ATPase and HCO3-ATPase, thiocyanate, perchlorate and azide were distributed as follows: N3 greater than CNS greater than ClO4. Thiocyanate inhibited non-competitively the HCO3-stimulated ATPase activity. The similarity was observed between HCO3-stimulated ATPase from rat kidney and bicarbonate-stimulated ATPase from other cells.
mesh_terms: D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000818:Animals; D000838:Anions; D001386:Azides / Q000494:pharmacology; D001639:Bicarbonates / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation / Q000187:drug effects; D007668:Kidney / Q000201:enzymology*; D007672:Kidney Cortex / Q000201:enzymology; D007679:Kidney Medulla / Q000201:enzymology; D008928:Mitochondria / Q000201:enzymology; D010472:Perchlorates / Q000494:pharmacology; D051381:Rats; D013861:Thiocyanates / Q000494:pharmacology
chemical_list: D000838:Anions; D001386:Azides; D001639:Bicarbonates; D010472:Perchlorates; D013861:Thiocyanates; D000251:Adenosine Triphosphatases
vernacular_title: HCO3- -stimuliruemaia ATF-aza pochek krysy