An endogenous inhibitor of N-methyltransferase activity and opiate receptor binding in rabbit tissue.
We have characterized and purified a peptide extracted from newborn rabbit brain, lung and liver. This peptide has a molecular weight of 1500 and has the ability to inhibit adult rabbit lung N-methyltransferase activity in vitro and can also bind to opiate receptor in rat brain homogenate.
D001923:Brain Chemistry; D005048:Etorphine / Q000378:metabolism; D008099:Liver / Q000032:analysis; D008168:Lung / Q000032:analysis / Q000201:enzymology; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D008970:Molecular Weight; D010455:Peptides / Q000302:isolation & purification / Q000494:pharmacology; D011957:Receptors, Opioid / Q000187:drug effects / Q000378:metabolism*; D014363:Tryptamines / Q000378:metabolism
D010455:Peptides; D011957:Receptors, Opioid; D014363:Tryptamines; D005048:Etorphine; D008780:Methyltransferases