Pancreatic islet cell carcinoma in a dog treated with streptozotocin.
After surgical removal of the primary tumor and recurrence of hypoglycemia, a dog with metastatic pancreatic islet cell carcinoma was treated with streptozotocin. Nephrotoxicosis resulted after a single administration of streptozotocin.
D007516:Adenoma, Islet Cell / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000139:chemically induced / Q000188:drug therapy* / Q000601:surgery; D004285:Dogs; D005260:Female; D007003:Hypoglycemia / Q000662:veterinary; D007328:Insulin / Q000097:blood; D007674:Kidney Diseases / Q000139:chemically induced / Q000662:veterinary; D009362:Neoplasm Metastasis; D010190:Pancreatic Neoplasms / Q000601:surgery / Q000662:veterinary*; D013311:Streptozocin / Q000009:adverse effects / Q000627:therapeutic use*
D007328:Insulin; D013311:Streptozocin