Regulation of de novo purine synthesis in human and rat tissue: role of oxidative pentose phosphate pathway activity and of ribose-5-phosphate and phosphoribosylpyrophosphate availability.
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology; D002478:Cells, Cultured; D004789:Enzyme Activation; D006801:Humans; D007962:Leukocytes / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008751:Methylene Blue / Q000494:pharmacology; D010428:Pentosephosphates / Q000378:metabolism*; D010710:Phosphates / Q000494:pharmacology; D010754:Phosphoribosyl Pyrophosphate / Q000378:metabolism*; D011687:Purines / Q000096:biosynthesis*; D051381:Rats; D012268:Ribose-Phosphate Pyrophosphokinase / Q000378:metabolism; D012267:Ribosemonophosphates / Q000378:metabolism*
D010428:Pentosephosphates; D010710:Phosphates; D011687:Purines; D012267:Ribosemonophosphates; D010754:Phosphoribosyl Pyrophosphate; D012268:Ribose-Phosphate Pyrophosphokinase; D001205:Ascorbic Acid; D008751:Methylene Blue