[Decrease in the radiation effect in the lymphoid organs of animals adapting to altitude].
Adaptation to altitude hypoxia exerts a positive effect on the cell density of lymph organs of gamma-irradiated animals. It also reduces radiation degradation of DNA, its availability to DNase in the nuclear chromatin and disorders in the activity of DNA polymerases. The role of inhibition of radiation-induced degradation of chromatin DNA in the protective effect of altitude adaptation on the cell density of lymph organs is discussed.
D000222:Adaptation, Physiological / Q000528:radiation effects*; D000531:Altitude; D000818:Animals; D004247:DNA / Q000528:radiation effects; D003851:Deoxyribonucleases / Q000528:radiation effects; D004789:Enzyme Activation / Q000528:radiation effects; D005720:Gamma Rays / Q000009:adverse effects; D000860:Hypoxia / Q000503:physiopathology; D008221:Lymphoid Tissue / Q000528:radiation effects*; D008297:Male; D010744:Phosphoric Monoester Hydrolases / Q000528:radiation effects; D051381:Rats; D013154:Spleen / Q000528:radiation effects; D013997:Time Factors
D004247:DNA; D003851:Deoxyribonucleases; D010744:Phosphoric Monoester Hydrolases
Snizhenie radiatsionnogo éffekta v limfoidnykh organakh zhivotnykh pri adaptatsii k vysokogor'iu.