Pituitary growth hormone cell adenoma with cytoplasmic tubular aggregates in the capillary endothelium.
Electron microscopy revealed the presence of cytoplasmic tubular aggregates in the capillary endothelium of a sparsely granulated growth hormone cell adenoma removed surgically from a 25-year-old female patient with acromegaly. To our knowledge, this is the second publication describing these structures in hypophysial growth hormone cell adenomas.
D000236:Adenoma / Q000098:blood supply / Q000378:metabolism / Q000648:ultrastructure*; D000328:Adult; D002196:Capillaries / Q000648:ultrastructure; D004727:Endothelium / Q000648:ultrastructure; D005260:Female; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D010911:Pituitary Neoplasms / Q000098:blood supply / Q000378:metabolism / Q000648:ultrastructure*
D013006:Growth Hormone