New insights into cholesterol dynamics.
Kinetic aspects of cholesterol dynamics are described, with flux from the gut, to the liver, to the tissues, and back to the liver and gut, with a discussion of modifying mechanisms, synthesis, and transport. Overproduction of cholesterol, and bile acid and cholesterol malabsorption, are related to clinical problems.
D001647:Bile Acids and Salts / Q000378:metabolism; D002784:Cholesterol / Q000096:biosynthesis / Q000378:metabolism*; D005227:Fatty Acids / Q000096:biosynthesis; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism*; D007700:Kinetics; D008075:Lipoproteins, HDL / Q000378:metabolism; D008077:Lipoproteins, LDL / Q000378:metabolism; D008079:Lipoproteins, VLDL / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008286:Malabsorption Syndromes / Q000378:metabolism; D009765:Obesity / Q000378:metabolism; D014280:Triglycerides / Q000097:blood; D014973:Xanthomatosis / Q000378:metabolism
D001647:Bile Acids and Salts; D005227:Fatty Acids; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D014280:Triglycerides; D002784:Cholesterol