Interferon inhibits mouse leukaemia virus release: an electron microscope study.
Scanning electron microscopy of AKR cells chronically infected with AKR mouse leukaemia virus revealed that the number of budding virions was greatly increased in interferon-treated cells. These results, together with previous biochemical findings, suggest that in this system, interferon inhibits a late stage of virus assembly or release.
D000406:AKR murine leukemia virus / Q000187:drug effects / Q000254:growth & development*; D000818:Animals; D002460:Cell Line; D002462:Cell Membrane / Q000187:drug effects; D007372:Interferons / Q000494:pharmacology*; D009052:Leukemia Virus, Murine / Q000254:growth & development*; D051379:Mice; D008855:Microscopy, Electron, Scanning; D014779:Virus Replication / Q000187:drug effects*
D007372:Interferons