[Interaction of spin-labeled saturated and unsaturated fatty acid derivatives with biological membrane lipid and protein components].
Interaction of saturated and unsaturated derivatives of spin-labelled fatty acids (2,2,6,6-tetramethyl-4-palmitoylpiperidil-l-oxyl (I) and synthetized by us 2,2,6,6-tetramethyl-4-oleoylpiperidil-1-oxyl (II) with sarcoplasmic reticulum membranes, retina rod outer segments and erythorocyte ghosts was studied. ESR spectra of the probe I are practically unresolved singlets, whereas ESR spectra of the probe II appear as more of less resolved triplet signals. The difference in ESR spectra of the probes I and II is the result of distribution of the probe I in pure lipid regions of membranes, the probe II being located both in lipid bilayer and hydrophobic areas of proteins.
D000818:Animals; D003497:Cyclic N-Oxides; D004578:Electron Spin Resonance Spectroscopy; D004910:Erythrocyte Membrane; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D006801:Humans; D066298:In Vitro Techniques; D008563:Membrane Lipids; D008565:Membrane Proteins; D010786:Photoreceptor Cells; D011817:Rabbits; D012519:Sarcoplasmic Reticulum; D013113:Spin Labels
D003497:Cyclic N-Oxides; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D008563:Membrane Lipids; D008565:Membrane Proteins; D013113:Spin Labels
Vzaimodeĭstvie spin-mechenykh proizvodnykh nasyshchennykh i nenasyshchennykh zhirnykh kislot s lipidnymi i belkovymi komponentami biologicheskikh membran