title: [Changes in the kinin system components and structure of the myocardium under the influence of antikinin preparations in allergic myocarditis in rabbits].
abstract: Experimental allergic myocarditis was induced in rabbits; a study was made of the effect on the kininogen content and on the activity of kininase in the myocardium, and on its morphological structure produced by anginine, contrical, aspirin, indometacine and epsilon-aminocapronic acid. The former two preparations were much more potent (in comparison with the others) in inhibiting the activation of the myocardial kinin system and promoted restoration of the morphological structure of the myocardium. Development of an allergic inflammation in the myocardium could be arrested or decreased by inhibition of the kinin system of the plasma and myocardium by specific agents.
mesh_terms: D015119:Aminocaproic Acid / Q000627:therapeutic use; D000818:Animals; D007611:Aprotinin / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D006321:Heart / Q000187:drug effects*; D006967:Hypersensitivity / Q000188:drug therapy / Q000503:physiopathology*; D007213:Indomethacin / Q000627:therapeutic use; D007704:Kininogens; D007705:Kinins / Q000037:antagonists & inhibitors*; D001121:Lysine Carboxypeptidase / Q000378:metabolism; D009205:Myocarditis / Q000188:drug therapy / Q000503:physiopathology*; D009206:Myocardium / Q000378:metabolism / Q000473:pathology*; D007703:Peptidyl-Dipeptidase A / Q000378:metabolism; D011727:Pyridinolcarbamate / Q000627:therapeutic use; D011817:Rabbits
chemical_list: D007704:Kininogens; D007705:Kinins; D011727:Pyridinolcarbamate; D007611:Aprotinin; D007703:Peptidyl-Dipeptidase A; D001121:Lysine Carboxypeptidase; D001241:Aspirin; D015119:Aminocaproic Acid; D007213:Indomethacin
vernacular_title: Izmeneniia komponentov kininovoĭ systemy i struktury miokarda pod vliianiem antikininovykh preparatov pri allergicheskom miokardite u krolikov