Characterization of L5178Y leukemic cells by phagocytosis, cytochemical methods, and membrane marker techniques.
Membrane marker techniques, endocytosis, and cytochemical methods were used to characterize L5178Y cells. L5178Y cells were found to have surface membrane immunoglobulin that typifies B-cells, and membrane receptors that are common to both B-cells and monocytes. L5178Y cells also have endocytic and enzymatic activities that are characteristic of monocytes. Thus L5178Y cells have the dual characteristics of B-cells and monocytes.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology / Q000473:pathology*; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology; D004705:Endocytosis; D007141:Immunoglobulin Fc Fragments; D007181:Inclusion Bodies, Viral; D007942:Leukemia, Experimental / Q000276:immunology / Q000473:pathology* / Q000503:physiopathology; D009000:Monocytes / Q000276:immunology / Q000473:pathology*; D011947:Receptors, Antigen, B-Cell; D012190:Retroviridae
D007141:Immunoglobulin Fc Fragments; D011947:Receptors, Antigen, B-Cell