Immediate endocrine and metabolic consequences of traumatic quadriplegia in a young woman.
Onset of paralysis by cervical spinal cord injury led immediately to temporary adrenocortical activation and, within 2 days, to sustained skin and bone breakdown. Urine cAMP was increased, blood parathyroid hormone, renin activity, and electrolytes were normal, and fluid and electrolytes balance became negative during the initial 6 days of paralysis.
D015065:17-Hydroxycorticosteroids / Q000097:blood; D000293:Adolescent; D001842:Bone and Bones / Q000378:metabolism; D002118:Calcium / Q000652:urine; D003094:Collagen / Q000378:metabolism; D000242:Cyclic AMP / Q000652:urine; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006909:Hydroxyproline / Q000378:metabolism; D008239:Lysine / Q000031:analogs & derivatives; D010281:Parathyroid Hormone / Q000097:blood; D010758:Phosphorus / Q000652:urine; D011782:Quadriplegia / Q000097:blood / Q000378:metabolism* / Q000652:urine; D012083:Renin / Q000097:blood; D013577:Syndrome; D014883:Water-Electrolyte Imbalance / Q000209:etiology
D015065:17-Hydroxycorticosteroids; D010281:Parathyroid Hormone; D010758:Phosphorus; D003094:Collagen; D000242:Cyclic AMP; D012083:Renin; D008239:Lysine; D006909:Hydroxyproline; D002118:Calcium; D006854:Hydrocortisone