Studies of human malignant lymphomas after treatment with endoxan. I. Cytochemical studies in the respiratory enzymes succinic dehydrogenase and cytochrome oxidase.
The respiratory enzymes succinic dehydrogenase and cytochrome oxidase were studied in normal lymph node and malignant lymphoma cells under the effect of endoxan treatment. It is concluded that the decrease in the respiratory enzymes in lymphoma cells may be taken as one of the outstanding differences between the neoplastic and normal tissues.
D003520:Cyclophosphamide / Q000627:therapeutic use*; D003576:Electron Transport Complex IV / Q000378:metabolism; D006801:Humans; D008223:Lymphoma / Q000188:drug therapy* / Q000201:enzymology / Q000648:ultrastructure; D013385:Succinate Dehydrogenase / Q000378:metabolism
D003520:Cyclophosphamide; D013385:Succinate Dehydrogenase; D003576:Electron Transport Complex IV