title: Lysosomal enzyme release associated with the invasion of rat liver by Novikoff hepatoma.
abstract: The lysosomes of both Novikoff heptoma and liver from Novikoff heptoma-bearing rats were found to be relatively intact structurally, lower in acid phosphatase activity, greatly depleted in number but with nearly normal membrane integrity when compared with normal liver.
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000201:enzymology* / Q000473:pathology; D008099:Liver / Q000201:enzymology* / Q000648:ultrastructure; D008113:Liver Neoplasms / Q000201:enzymology* / Q000473:pathology; D008247:Lysosomes / Q000201:enzymology* / Q000502:physiology; D008297:Male; D009374:Neoplasms, Experimental / Q000201:enzymology / Q000473:pathology; D010539:Permeability; D051381:Rats
chemical_list: D000135:Acid Phosphatase