Plasma ACTH levels in stressed and nonstressed adrenalectomized rats.
Following adrenalectomy there is a triphasic response of ACTH secretion characterized by an initial high rise immediately following the adrenalectomy, secondary to the stress of the procedure. This is followed by a fall to resting ACTH secretion until a steady state is reached 1 to 2 weeks following adrenalectomy at levels about 10 times normal. The ability to respond to stress with increased ACTH secretion is not lost at any time following adrenalectomy.
D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000097:blood* / Q000378:metabolism; D000818:Animals; D010902:Pituitary Gland / Q000378:metabolism; D051381:Rats; D013312:Stress, Physiological / Q000097:blood*
D000324:Adrenocorticotropic Hormone