title: [Metastasizing islet cell carcinoma of the pancreas in a 10-year-old girl (author's transl)].
abstract: A medullary islet cell carcinoma of the pancreas with liver and peritoneal metastases was found at autopsy of a 10-year-old girl. Ultrastructurally, the carcinoma cells showed typical secretion granules resembling prevailingly A1 (D) cell granules in pancreatic islets. Silver impregnation according to Hellerström and Hellman (1960) for demonstration of A1 islet cells was moderately positive in the tumor cells. Therefore, it is suggested that the presented metastasizing islet cell carcinoma may have derived from A1 islet cells.
mesh_terms: D007516:Adenoma, Islet Cell / Q000648:ultrastructure*; D002277:Carcinoma / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications; D008854:Microscopy, Electron; D009362:Neoplasm Metastasis; D010190:Pancreatic Neoplasms / Q000648:ultrastructure*; D010534:Peritoneal Neoplasms / Q000150:complications
vernacular_title: Metastasierendes Inselzellkarizinom des Pankreas bei einem 1Ojährigen Mädchen