title: Antibody like activities against cholesterol ester in anti-LDL antiserum. An observation on the surface of LDL.
abstract: The antibody like activities against cholesterol and cholesterol ester were examined by means of radioimmunoassay system, immunolysis of liposomes containing cholesterol and other steroids. In comparison with anti-etiocholenic acid antiserum and anti-cholesterol succinate antiserum, it was proved that anti-LDL antiserum contained 2 kinds of antibodies, one was specific to the structure of cholesterol skeleton and other was specific to the whole structure of cholesterol ester. LDL only combined with anti-cholesterol succinate antibody resulting with the inhibition of the interaction between sheep red cell sensitized by cholesterol succinate and anti-cholesterol succinate antiserum by means of passive hemagglutionation reaction.
mesh_terms: D000818:Animals; D000918:Antibody Specificity; D002784:Cholesterol / Q000031:analogs & derivatives* / Q000276:immunology; D002788:Cholesterol Esters / Q000276:immunology*; D006385:Hemagglutination Inhibition Tests; D007106:Immune Sera; D008077:Lipoproteins, LDL / Q000276:immunology*; D008081:Liposomes / Q000276:immunology; D011817:Rabbits / Q000276:immunology; D011863:Radioimmunoassay; D012756:Sheep / Q000276:immunology
chemical_list: D002788:Cholesterol Esters; D007106:Immune Sera; D008077:Lipoproteins, LDL; D008081:Liposomes; D002784:Cholesterol