Demonstration of Marek's disease tumor-associated surface antigen in chickens infected with nononcogenic Marek's disease virus and herpesvirus of turkeys.
The presence of Marek's disease tumor-associated surface antigen (MATSA) was demonstrated on spleen cells from P-line chickens inoculated 5--6 days earlier with herpesvirus of turkeys and SB-1 (a nononcogenic Marek's disease virus). Antisera against MATSA expressed on five Marek's disease lymphoblastoid cell lines were able to recognize the MATSA present on SB-1-infected spleen cells. No viral membrane antigens and only a low incidence of viral internal antigens could be demonstrated.
D000818:Animals; D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D000956:Antigens, Viral; D002645:Chickens; D006566:Herpesviridae Infections / Q000276:immunology*; D007109:Immunity; D008380:Marek Disease / Q000276:immunology*; D013154:Spleen / Q000276:immunology
D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D000956:Antigens, Viral