[Effect of "carbostimulin", vitamin D 3 and their mixture on bone tissue regeneration].
Healing of the bone injury in rabbits was studied as affected by carbostimulin and its mixture with vitamin D3. Some biochemical indexes: the content of sialic acids, calcium and citric acid in blood serum of the animals, intensity of 14C incorporation from NaH14CO3 into the regenerated bone tissue and its proteins as well as histological studies, data, evidence for a positive effect of the mentioned preparations on the bone substance regeneration in the animals under experiment. So. the content of sialic acids in blood serum normalizes on the 10th day after the operation mostly in the animals which were administered the mixture of the preparations and in which the most pronounced hypercalcemia is observed. Incorporation of 14C from NaH14CO3 into the regenerated tissue and its proteins is most intensive in the same animals.
D000818:Animals; D001639:Bicarbonates / Q000378:metabolism; D001861:Bone Regeneration / Q000187:drug effects*; D001842:Bone and Bones / Q000187:drug effects / Q000378:metabolism; D002118:Calcium / Q000097:blood; D002250:Carbon Radioisotopes; D002762:Cholecalciferol / Q000494:pharmacology*; D002951:Citrates / Q000097:blood; D007553:Isotope Labeling; D011817:Rabbits; D012794:Sialic Acids / Q000097:blood
D001639:Bicarbonates; D002250:Carbon Radioisotopes; D002951:Citrates; D012794:Sialic Acids; D002762:Cholecalciferol; D002118:Calcium
Vpliv karbostimulinu ĭ vitaminu D3 ta ĭkh sumishi na regeneratsiiu kistkovoĭ tkanini.