25-Hydroxycholecalciferol and 1, 25-dihydroxycholecalciferol are potent inhibitors of cholesterol biosynthesis by normal and leukemic (L2C) guinea pig lymphocytes.
D000818:Animals; D002762:Cholecalciferol / Q000494:pharmacology; D002784:Cholesterol / Q000096:biosynthesis*; D004100:Dihydroxycholecalciferols / Q000494:pharmacology*; D006168:Guinea Pigs; D006887:Hydroxycholecalciferols / Q000494:pharmacology*; D007700:Kinetics; D007942:Leukemia, Experimental / Q000378:metabolism*; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D013329:Structure-Activity Relationship
D004100:Dihydroxycholecalciferols; D006887:Hydroxycholecalciferols; D002762:Cholecalciferol; D002784:Cholesterol