A Drosophila mutant with a temperature-sensitive block in nerve conduction.
A mutant, napts (no action potential, temperature-sensitive), is described in which axonal conduction fails at high temperature. Synaptic transmission at the larval neuromuscular junction is unimpaired. Larvae and adults are rapidly paralyzed at restrictive temperatures; they recover rapidly when the temperature is decreased. The mutant gene is recessive and is located on the second chromosome at map position 56.
D000200:Action Potentials; D000818:Animals; D002874:Chromosome Mapping; D004330:Drosophila / Q000235:genetics*; D005808:Genes, Recessive; D007814:Larva; D009154:Mutation; D009431:Neural Conduction; D009435:Synaptic Transmission; D013696:Temperature