Influence of triethylcholine on autonomic transmission in vitro.
The influence of triethylcholine (TEC) on isolated autonomic transmission has been investigated in some isolated preparations. The guinea-pig hypogastric nerve-vas deferens-urinary bladder preparation for studying both cholinergic and adrenergic transmission simultaneously is described. Incubation with TEC caused impairment of cholinergic transmission but failed to inhibit adrenergic transmission. Employing TEC as a pharmacological tool, no evidence for a cholinergic link could be obtained in adrenergic transmission in the isolated vas deferens and rabbit ileum preparations.
D000818:Animals; D001341:Autonomic Nervous System / Q000187:drug effects*; D002794:Choline / Q000031:analogs & derivatives* / Q000494:pharmacology*; D004558:Electric Stimulation; D006168:Guinea Pigs; D007082:Ileum / Q000294:innervation; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D011817:Rabbits; D051381:Rats; D009435:Synaptic Transmission / Q000187:drug effects*; D001743:Urinary Bladder / Q000294:innervation; D014649:Vas Deferens / Q000294:innervation
D002794:Choline