title: Chemotherapy of malignant fibrous histiocytoma: a Southwest Oncology Group report.
abstract: Malignant fibrous histiocytoma is a rare tumor, which constitutes 3-4% of the soft tissue sarcomas. It occurs with maximum frequency in the sixth and seventh decades of life and has a distinct male preponderance. In two-thirds of the patients an extremity is the primary site and approximately one-half develop local recurrences and one-half, distant metastases. Response to combination chemotherapy occurred in 33%, a rate similar to that seen in other sarcomas.
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D005069:Evaluation Studies as Topic; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012983:Soft Tissue Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents