[Pharmacological suppression of paradoxical sleep in the newborn rat (author's transl)].
In an attempt to suppress paradoxical sleep (PS) an intracerebral injection of 6 0HDA was carried out on rat faetuses at a gestational age of 16-20 days. In these animals a delay in maturation occurred compared to controls, the only modification of sleep being observed however, related to the circadian rhythmn of PS. The possible reasons for this are discussed within the framework of a concept relating paradoxical sleep to cerebral maturation.
D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000187:drug effects* / Q000254:growth & development; D002940:Circadian Rhythm / Q000187:drug effects; D005865:Gestational Age; D006892:Hydroxydopamines / Q000494:pharmacology*; D009043:Motor Activity / Q000187:drug effects; D051381:Rats; D012895:Sleep, REM / Q000187:drug effects*
D006892:Hydroxydopamines
Essai de suppression pharmacologique du sommeil paradoxal chez le rat nouveau-né.