title: Assignment of the gene for adenosine kinase to chromosome 14 in Mus musculus by somatic cell hybridization.
abstract: Evidence is presented for the assignment of the gene for adenosine kinase to Mus musculus chromosome 14 by synteny testing and karyotypic analysis of mouse X Chinese hamster somatic cell hybrid clones. ADOK and two enzymes previously mapped to mouse chromosome 14, NP and ES-10, were expressed concordantly in 29 hybrid clones. Chromosome analysis confirmed this assignment. Syntenic evidence is also presented using several clones of a gene transfer system in which the gene for human HPRT had integrated into modified mouse chromosome 14's.
mesh_terms: D000248:Adenosine Kinase / Q000235:genetics*; D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured; D002874:Chromosome Mapping; D002999:Clone Cells; D006224:Cricetinae; D005796:Genes; D006822:Hybrid Cells / Q000201:enzymology*; D051379:Mice; D010770:Phosphotransferases / Q000235:genetics*
chemical_list: D010770:Phosphotransferases; D000248:Adenosine Kinase