Formation of larger cell aggregates by transformed cells: an in vitro index of cell transformation.
Virus-transformed rat and hamster embryonic cells formed larger cell aggregates than those formed by normal counterpart cells within 1-3 days. This aggregate property correlated with growth in soft agar and tumorigenicity.
D000818:Animals; D002449:Cell Aggregation; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured; D006224:Cricetinae; D051381:Rats; D009053:Sarcoma Viruses, Murine; D012513:Sarcoma, Experimental / Q000473:pathology; D013539:Simian virus 40