title: [Malignant insuloma. Evaluation of the response to treatment with streptozotocin, using selective arteriography of the celiac axis].
abstract: A patients with metastatic insulin-producing islet-cell carcinoma has been treated with Streptozotocin intravenously and studied by selective celiac angiography during treatment. A 50% decrease of the tumor's size has been demonstrated by this technique after a total dose of 19 grams of the drug together with return to normal of the serum-insulin and blood-glucose values. The usefulness of angiography in evaluating the tumor response to Streptozotocin and in managing chemotherapy is discussed.
mesh_terms: D007516:Adenoma, Islet Cell / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000792:Angiography; D002445:Celiac Artery / Q000000981:diagnostic imaging; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D013311:Streptozocin / Q000627:therapeutic use*
chemical_list: D013311:Streptozocin
vernacular_title: Insuloma maligno. Valutazione della risposta alla terapia con streptozotocina mediante arteriografia selettiva del tripode celiaco.