Effect of prolactin on tetracycline binding to human spermatozoa.
The effect of different concentrations of prolactin (0 to 60 ng) on the release of tetracycline from human spermatozoa labeled with 7-3H-tetracycline hydrochloride was studied. Prolactin significantly enhanced the release of bound tetracycline, indicating that prolactin may influence the processes associated with sperm capacitation.
D000242:Cyclic AMP / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D009994:Osmolar Concentration; D011388:Prolactin / Q000494:pharmacology*; D013075:Sperm Capacitation; D013094:Spermatozoa / Q000378:metabolism*; D013752:Tetracycline / Q000378:metabolism*; D013997:Time Factors
D011388:Prolactin; D000242:Cyclic AMP; D013752:Tetracycline