title: [Effect of differentiation of GABA levels in various cell cultures].
abstract: The effect of factors inducing somatic differentiation on cellular GABA level has been investigated. C6 glial cells from a rat astrocytoma present a significantly higher GABA level than the other glial or neuronal cells studied. A significant decrease in GABA levels in most cases parallels the somatic differentiation induced either by withdrawal of fetal serum, or by addition of dibutyryl cyclic AMP to the culture medium.
mesh_terms: D000613:Aminobutyrates / Q000032:analysis*; D000818:Animals; D001253:Astrocytes / Q000032:analysis*; D003994:Bucladesine / Q000494:pharmacology; D002454:Cell Differentiation; D002460:Cell Line / Q000187:drug effects; D002999:Clone Cells / Q000032:analysis*; D006224:Cricetinae; D005312:Fetal Blood; D051379:Mice; D009457:Neuroglia / Q000032:analysis*; D009474:Neurons / Q000032:analysis*; D051381:Rats; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
chemical_list: D000613:Aminobutyrates; D005680:gamma-Aminobutyric Acid; D003994:Bucladesine
vernacular_title: Effet de la différenciation sur la teneur en GABA dans diverses cultures de cellules.