Cardiac localization of 99mTc-(Sn)-pyrophosphate following irradiation of the chest.
Of 70 consecutive cancer patients referred from radiotherapy for bone scans, 32% showed cardiac uptake of 99mTc-(Sn)-pyrophosphate; only 9% of a control group showed this uptake. Of those with prior left hemithorax irradiation, 60% showed cardiac uptake; only 12% of those with irradiation elsewhere showed this phenomenon (p less than .01). The patients who had no increased uptake tended to have shorter irradiation-to-scan time intervals (less than 10 months) than those who did show increased uptake (mean of 22 months).
D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000175:diagnosis*; D001943:Breast Neoplasms / Q000532:radiotherapy; D011756:Diphosphates; D005260:Female; D006689:Hodgkin Disease / Q000532:radiotherapy; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D009206:Myocardium; D011877:Radionuclide Imaging; D011878:Radiotherapy / Q000009:adverse effects*; D013667:Technetium; D013909:Thorax / Q000528:radiation effects
D011756:Diphosphates; D013667:Technetium