Deep tendon reflex in Eaton-Lambert syndrome.
The mechanism of absent or decreased deep tendon reflex in Eaton-Lambert syndrome was studied. There was no evidence suggestive of the presence of a neuropathy. On the other hand, a brief (about 10 seconds) maximal voluntary contraction made the absent deep tendon reflexes elicitable, which suggests that the block of neuromuscular transmission in Eaton-Lambert syndrome is responsible for the absent or decreased deep tendon reflex. Such enhancement of the decreased deep tendon reflex in Eaton-Lambert syndrome might be helpful in differentiating neuropathy and Eaton-Lambert syndrome.
D001984:Bronchial Neoplasms / Q000150:complications; D018288:Carcinoma, Small Cell / Q000150:complications; D004576:Electromyography; D006146:Guanidines / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000188:drug therapy / Q000503:physiopathology*; D012023:Reflex, Monosynaptic; D012026:Reflex, Stretch
D006146:Guanidines