Transmission of excitation from muscle to nerve under in situ conditions.
In order to investigate the excitatory effect of the muscle on the adjacent nerve experiments were performed on nerve-muscle and whole leg preparations of the frog. The results showed that muscular activity could generate excitation of the nerve in contact with the muscle under in situ circumstances, and that a well-defined part of the muscle could play a significant role in the transmission of excitation from muscle to nerve. The results support the hypothesis of being an additional way for muscle activity to influence the regulatory mechanism of the nerve-muscle function during excitatory processes.
D000200:Action Potentials; D000818:Animals; D001001:Anura; D066298:In Vitro Techniques; D009132:Muscles / Q000502:physiology; D009469:Neuromuscular Junction / Q000502:physiology*; D011893:Rana esculenta; D009435:Synaptic Transmission