title: [Organ and tissue cyclic adenosine-3', 5'-monophosphate during the process of the body's adaptation to extreme factors].
abstract: Various by nature extreme factors (hypoxic hypoxia, CO intoxication, chemical influence, noise and hypokinesia) caused similar changes in cAMP levels in different organs of albino rats (liver, the great cerebral hemispheres, heart). There was a significant increase in cAMP concentrations during the first stages of the influence and a progressive fall when the influence was continued. This fall was particularly expressed when the extreme factors used were of marked intensity. The authors consider the universality of the ascertained regularity to be a reflection of one of the central adaptive mechanisms of cell and the organism as a whole.
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism; D002249:Carbon Monoxide Poisoning / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism*; D004811:Epichlorohydrin / Q000506:poisoning; D000860:Hypoxia / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D013312:Stress, Physiological / Q000378:metabolism*; D013343:Styrenes / Q000506:poisoning
chemical_list: D013343:Styrenes; D004811:Epichlorohydrin; D000242:Cyclic AMP
vernacular_title: Tsiklicheskiĭ adenozin-3'5'-monofosfat v organakh i tkaniakh v protsesse adaptatsii organizma k ekstremal'nym vozdeĭstviiam.