title: Canine cutaneous histiocytoma: ultrastructural and cytochemical observations.
abstract: Five canine cutaneous histiocytomas were studied by electron microscopy and esterase cytochemistry. The tumor cells contained irregular nuclei, characteristic lysosomal granules, and perinuclear microfilaments. The cells showed activity with alpha-naphthyl acetate esterase stains. These characteristics are evidence that this tumor originates from the mononuclear phagocyte system.
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000201:enzymology / Q000473:pathology; D004285:Dogs; D004950:Esterases / Q000378:metabolism; D018219:Histiocytoma, Benign Fibrous / Q000201:enzymology / Q000648:ultrastructure / Q000662:veterinary*; D012878:Skin Neoplasms / Q000201:enzymology / Q000648:ultrastructure / Q000662:veterinary*
chemical_list: D004950:Esterases