[Cytological and histochemical studies on cell cultures infected with bovine herpesvirus type 2].
Cell cultures of embryonic calf kidney which had been infected with bovid herpes virus 2 were examined for cytological and histochemical changes. The morphological changes recorded from cells damaged by virus infection included the formation of gigant syncytial cells and intranuclear inclusions of Cowdry Type A. The cytological changes in the infected cells were accompanied by variation in enzyme activity. Recordable were rise in lactate dehydrogenase and alkaline phosphatase as well as decline in succinate dehydrogenase and acid phosphate activity. These phenomena were found to have resulted from impediment of cell metabolism by virus action.
D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D002417:Cattle; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D004622:Embryo, Mammalian; D006564:Herpesviridae; D006566:Herpesviridae Infections / Q000473:pathology; D007181:Inclusion Bodies, Viral; D007668:Kidney / Q000201:enzymology / Q000473:pathology*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D013385:Succinate Dehydrogenase / Q000378:metabolism; D014776:Virus Cultivation
D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase
Zytologische und histochemische Untersuchungen an mit bovinem Herpesvirus Typ2 infizierten Zellkulturen