Cyclic adenosine monophosphate production by embryonic chick cells.
Cells dissociated from 1-day-old chick embryos produce a pulse of cyclic adenosine monophosphate (cyclic AMP) when stimulated with cyclic AMP. There is a stimulus threshold concentration of about 10(-8) molar cyclic AMP and an upper limit, above which the response is suppressed, of about 6 X 10(-6) molar. The response occurs within 5 seconds of stimulation and corresponds to an average pulse size in the range of 10(7) molecules per cell.
D000818:Animals; D002642:Chick Embryo / Q000166:cytology / Q000378:metabolism*; D000242:Cyclic AMP / Q000096:biosynthesis* / Q000494:pharmacology; D066298:In Vitro Techniques; D011865:Radioisotope Dilution Technique
D000242:Cyclic AMP