title: A synergistic interaction between the teratogenic effect of trypan blue and dietary deficiency in the rat.
abstract: There was an increased incidence, compared to controls, of exencephaly and microphthalmia in the offspring of rats fed a vitamin D deficient diet and injected with trypan blue on day 9 of gestation. Oral vitamin D did not reverse the effect.
mesh_terms: D000014:Abnormalities, Drug-Induced; D000818:Animals; D002762:Cholecalciferol / Q000494:pharmacology; D005260:Female; D005865:Gestational Age; D011247:Pregnancy; D051381:Rats; D013723:Teratogens; D014343:Trypan Blue / Q000633:toxicity*; D014808:Vitamin D Deficiency
chemical_list: D013723:Teratogens; D002762:Cholecalciferol; D014343:Trypan Blue