title: Spontaneous tumors and common diseases in two colonies of Syrian hamsters. II. Respiratory tract and digestive system.
abstract: Spontaneous respiratory tract neoplasms in Syrian hamsters occurred in almost equal frequencies in two colonies: 3% in the Eppley Colony (EC) and 3.6% in the Hannover Colony (HC). Neoplasms were in the nasal cavity, trachea, and lungs, and most were benign; however, 2 adenocarcinomas of the nasal cavity (EC) and 1 adenocarcinoma of the larynx (HC) were found. The incidence of digestive tract tumors showed a more marked difference than that of the respiratory tract: 7% in the EC and 23% in the HC. Digestive tract tumors accounted for 15 and 41% of all tumors in the EC and HC, respectively. All EC digestive tract neoplasms were benign and occurred mostly in males; 19 (83%) were forestomach papillomas and the remaining 4 )17%) were liver hemangioendotheliomas (2) and pancreatic duct adenomas (2). In the HC, almost 50% of the digestive tract neoplasms were malignant and most frequent in females. These tumours include 19(42%) intestinal adenocarcinomas, 18(40%) liver neoplasms (hemangioendotheliomas, cholangiomas, cholangiocarcinomas), 5 (13%) forestomach papillomas, and 2 (4%) gallbladder polyps. The morphology of these neoplasms was reported.
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D002759:Adenoma, Bile Duct / Q000473:pathology; D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000473:pathology; D006224:Cricetinae; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000453:epidemiology* / Q000473:pathology; D006390:Hemangioendothelioma / Q000473:pathology; D007822:Laryngeal Neoplasms / Q000473:pathology; D008113:Liver Neoplasms / Q000473:pathology; D008297:Male; D008647:Mesocricetus; D009374:Neoplasms, Experimental / Q000453:epidemiology / Q000473:pathology; D009669:Nose Neoplasms / Q000473:pathology; D010212:Papilloma / Q000473:pathology; D011127:Polyps / Q000473:pathology; D012142:Respiratory Tract Neoplasms / Q000453:epidemiology* / Q000473:pathology; D012737:Sex Factors