title: [Advances in the treatment of malignant tumors in childhood: Wilm's tumor as an example (author's transl)].
abstract: The advances in the treatment of the Wilm's tumor have been made both surgically and in the conservative field. Extirpation through a lateral incision has given way to the broad transabdominal exposure. Inoperable tumors are very rare. Cytostatics like actinomycin D and vincristine are already applied intraoperatively. The choice of cytostatic and the duration of cytostatic therapy is adjusted to the intraoperative staging. The Society for Pediatric Oncology has worked out a modified plan of treatment in accordance with the growth of the tumor, in addition irradiation is applied according to the tumor staging. The results are stated as between 60 and 70%, the histology of the tumor and the age of the child, in addition to the growth of the tumor, being especially important.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003609:Dactinomycin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000628:therapy*; D008175:Lung Neoplasms / Q000628:therapy; D008297:Male; D009362:Neoplasm Metastasis; D009392:Nephrectomy / Q000379:methods; D011182:Postoperative Care; D011379:Prognosis; D014750:Vincristine / Q000627:therapeutic use; D009396:Wilms Tumor / Q000628:therapy*
chemical_list: D003609:Dactinomycin; D014750:Vincristine
vernacular_title: Fortschritte in der Behandlung maligner Tumoren im Kindesalter. Am Beispiel des Wilms-Tumors.