[Self-association of 5'-GMP: nucelation by potassium ions].
23Na and 39K nuclear magnetic resonance are used to follow the self-assocation of 5'-GMP in aqueous solutions. For a 0,1 M concentration in 5'-GMP, large aggregates are formed only in presence of the potassium ion, at greater than 0.2 M concentrations. They do not appear with the other alkali metal cations. A plausible explantation is inclusion of the cation in the central cavity of 5'-GMP tetramers, with a marked selectivity in favor of potassium.
D055598:Chemical Phenomena; D002621:Chemistry; D006150:Guanine Nucleotides; D006157:Guanosine Monophosphate; D006860:Hydrogen Bonding; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D011188:Potassium
D006150:Guanine Nucleotides; D006157:Guanosine Monophosphate; D011188:Potassium
L'auto-assemblage du 5'-GMP: nucléation par les ions potassium.