Histopathology of carcinomas of the liver in mice ingesting dieldrin or aldrin.
C3HeB/Fe male and female mice, ingesting 10 ppm of the pesticides dieldrin or aldrin in the diet, developed highly significant incidences of carcinomas of the liver. The carcinomas varied from well differentiated to poorly differentiated and undifferentiated and were capable of metastasis.
D002759:Adenoma, Bile Duct / Q000139:chemically induced* / Q000473:pathology; D000452:Aldrin / Q000633:toxicity*; D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000139:chemically induced* / Q000473:pathology; D004026:Dieldrin / Q000633:toxicity*; D005260:Female; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D009362:Neoplasm Metastasis; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000473:pathology
D004026:Dieldrin; D000452:Aldrin