Isolation of Epstein-Barr virus from cultured cells of a patient with Hodgkin's disease.
The suspension lymphoblastoid cell line named ChSL-1 was established from the tumor node of a patient with Hodgkin's disease. The cells of this culture produce a virus with morphological and physicochemical properties of herpes viruses. Immunologic study of the isolated virus demonstrated great similarity with the Epstein-Barr virus (EBV).
D000368:Aged; D000818:Animals; D000914:Antibodies, Viral; D002051:Burkitt Lymphoma / Q000276:immunology; D002478:Cells, Cultured; D002499:Centrifugation, Density Gradient; D006224:Cricetinae; D004854:Herpesvirus 4, Human / Q000276:immunology / Q000302:isolation & purification*; D006689:Hodgkin Disease / Q000382:microbiology* / Q000648:ultrastructure; D006801:Humans; D051379:Mice; D009303:Nasopharyngeal Neoplasms / Q000276:immunology
D000914:Antibodies, Viral