title: [Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome].
abstract: The therapeutics results with the use of different drugs (diazepam, nitrazepam, clonazepam, diphenylhydantoin, barbiturates--phenobarbital and primidone--, sodium dipropylacetate and ACTH) in twenty-nine patients with Lennox--Gastaut syndrome are carefully analysed. The effect of each drug on seizures (tonic, tonic-clonic, clonic, myoclonic or myoclonic-atonic, atonic and atypical absences) during the first month of each treatment is discussed. The "specific" use of each drug on the various forms of epileptic seizures is determined and the possibility of crisis control with reduction of the drugs dosage is verified.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use; D000927:Anticonvulsants / Q000008:administration & dosage / Q000627:therapeutic use*; D001463:Barbiturates / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002998:Clonazepam / Q000627:therapeutic use; D003975:Diazepam / Q000627:therapeutic use; D004569:Electroencephalography; D004827:Epilepsy / Q000145:classification / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009567:Nitrazepam / Q000627:therapeutic use; D010634:Phenobarbital / Q000627:therapeutic use; D010672:Phenytoin / Q000627:therapeutic use; D011324:Primidone / Q000627:therapeutic use; D012640:Seizures / Q000188:drug therapy*; D013036:Spasms, Infantile / Q000188:drug therapy; D013577:Syndrome
chemical_list: D000927:Anticonvulsants; D001463:Barbiturates; D011324:Primidone; D002998:Clonazepam; D010672:Phenytoin; D000324:Adrenocorticotropic Hormone; D009567:Nitrazepam; D003975:Diazepam; D010634:Phenobarbital
vernacular_title: Efeito de medicamentos sobre tipos eletroclínicos de crises epilépticas na síndrome de Lennox-Gastaut.