[Study of the antigenic properties of herpesvirus strains isolated from herpetic lesions at different sites].
The antigenic properties of 15 strains of hepesvirus isolated from herpetic lesions of different localization were studied. The serotype of each strain was established by the neutralization tests with hyperimmune sera to the reference type 1 and 2 strains: the cross-neutralization tests revealed antigenic relationships between the strains of 1 and 2 serotypes. Most strains isolated from lesions of the genitalia belonged to type 2, although one strain isolated in herpes genitalis belonged to type 1, and 2 strains isolated from facial lesions also belonged to type 2. These results confirm the necessity of using inactivated polyvaccine prepared from herpesvirus strains of antigenic types 1 and 2 for relapse control therapy instead of using monovalent type 1 and type 2 vaccines as reported by foreign authors.
D000956:Antigens, Viral / Q000032:analysis*; D002478:Cells, Cultured; D005260:Female; D005831:Genital Diseases, Female / Q000382:microbiology*; D005832:Genital Diseases, Male / Q000382:microbiology*; D006566:Herpesviridae Infections / Q000382:microbiology*; D006801:Humans; D007106:Immune Sera / Q000302:isolation & purification; D008297:Male; D009500:Neutralization Tests; D012008:Recurrence; D012703:Serotyping; D018139:Simplexvirus / Q000276:immunology* / Q000302:isolation & purification; D012874:Skin Diseases, Infectious / Q000382:microbiology*
D000956:Antigens, Viral; D007106:Immune Sera
Izuchenie antigennykh svoĭstv shtammov virusa gerpesa, vydelennykh iz gerpeticheskikh porazheniĭ razlichnoĭ lokalizatsii.