[Islet cell tumor with diarrhea and diabetes (glucagonoma?) associated with hyperparathyroidism. Long-term results of local-regional treatment with streptozotocin].
A case report of endocrine pancreatic tumour associated with diabetes and hyperparathyroidism is presented. Some arguments are in favour of a glucagonoma. Despite the absence of beta-cells in tumour, an exceptional result was obtained by use of Streptozotocin. This case brings up the relations between endocrine pancreatic tumours and parathyroid, and may be included in polyglandular adenoma syndrome.
D007516:Adenoma, Islet Cell / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism; D000328:Adult; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000378:metabolism; D003967:Diarrhea / Q000150:complications*; D005934:Glucagon / Q000378:metabolism; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism; D007328:Insulin / Q000627:therapeutic use; D007515:Islets of Langerhans / Q000378:metabolism; D008297:Male; D013311:Streptozocin / Q000627:therapeutic use
D007328:Insulin; D013311:Streptozocin; D005934:Glucagon
Tumeur insulaire avec diarrhée et diabète (glucagonome?) associée à un hyperparathyroïdisme. Résultat éloigné du traitement par la streptozotocine loco-régionale.