Worldwide controversies in gestational trophoblastic neoplasms.
This article reviews worldwide controversies concerning gestational trophoblastic neoplasms (hydatidiform mole, invasive mole, and choriocarcinoma). The epidemiology, endocrinology, histopathologic grading, classification, diagnosis, treatment, management and follow-up (including chemotherapy, irradiation, and immunotherapy) of gestational trophoblastic neoplasms - particularly molar pregnancies - are discussed; and ways to help create a standardized classification system and provide optimal treatment for each type of patient are suggested.
D006063:Chorionic Gonadotropin / Q000097:blood; D003609:Dactinomycin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000188:drug therapy / Q000628:therapy; D008727:Methotrexate / Q000627:therapeutic use; D011247:Pregnancy; D014328:Trophoblastic Neoplasms / Q000145:classification / Q000188:drug therapy / Q000276:immunology; D014594:Uterine Neoplasms / Q000145:classification / Q000188:drug therapy / Q000276:immunology / Q000628:therapy
D006063:Chorionic Gonadotropin; D003609:Dactinomycin; D008727:Methotrexate