title: In vitro RNA synthesis in nuclei from herpes simplex virus infected cells: effects of ultraviolet-irradiated, defective and bromodeoxyuridine-resistant virus preparations.
abstract: Transcription of virus DNA was detectable in vitro in nuclei isolated from cells infected with wild type and bromodeoxyuridine (BUdR)-resistant herpes simplex virus type 1 but was suppressed in nuclei of cells infected with ultraviolet irradiated or defective virus or cells treated with BUdR during infection.
mesh_terms: D001973:Bromodeoxyuridine / Q000494:pharmacology; D002460:Cell Line; D002467:Cell Nucleus / Q000378:metabolism; D004279:DNA, Viral / Q000378:metabolism; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D003673:Defective Viruses / Q000378:metabolism; D012367:RNA, Viral / Q000096:biosynthesis*; D018139:Simplexvirus / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D014158:Transcription, Genetic; D014466:Ultraviolet Rays
chemical_list: D004279:DNA, Viral; D012367:RNA, Viral; D012321:DNA-Directed RNA Polymerases; D001973:Bromodeoxyuridine