Inhibition of adsorption of West-Nile and herpes simplex viruses by procaine.
The effect of the local anaesthetic drug procaine on the adsorption of two enveloped viruses was studied. Physiological concentrations of the drug (7 X 10(-3)--7 X 10(-2) M) strongly inhibited the adsorption of both West-Nile and herpes viruses as determined by plaque assay and the infective center assay.
D000327:Adsorption; D002460:Cell Line; D011343:Procaine / Q000494:pharmacology*; D018139:Simplexvirus / Q000187:drug effects* / Q000254:growth & development; D010948:Viral Plaque Assay; D014902:West Nile virus / Q000187:drug effects* / Q000254:growth & development
D011343:Procaine