Cholesterol synthesis in freshly isolated human leukocytes.
Cholesterol synthesis has been studied in human leukocytes shortly after the isolation from healthy subjects. Not delipidated human serum reduced the cholesterol synthesis when added to the incubation medium. A similar effect was obtained when the leukocytes were incubated in the presence of physiological concentrations of low density lipoproteins.
D002478:Cells, Cultured; D002784:Cholesterol / Q000096:biosynthesis*; D003470:Culture Media; D006801:Humans; D007962:Leukocytes / Q000378:metabolism*; D008077:Lipoproteins, LDL / Q000494:pharmacology
D003470:Culture Media; D008077:Lipoproteins, LDL; D002784:Cholesterol