Cyclic nucleotides and prostaglandins (PGs) produced by the rabbit oviduct: effects of estrogen treatment.
Levels of cyclic AMP and cyclic GMP have been measured in oviducts of rabbits killed 68 hr after injection of human chorionic gonadotrophin (HCG) to induce ovulation. cAMP and cGMP levels were higher in the isthmus than in the ampulla. Estrogen treatment given at the same time as HCG increased cGMP levels. Levels of PGE and PGF in blood draining the oviduct were low and showed no effect of estrogen treatment at 68 hr after HCG.
D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D000242:Cyclic AMP / Q000378:metabolism; D006152:Cyclic GMP / Q000378:metabolism; D004967:Estrogens / Q000494:pharmacology*; D005187:Fallopian Tubes / Q000187:drug effects / Q000378:metabolism*; D005260:Female; D009712:Nucleotides, Cyclic / Q000096:biosynthesis*; D011453:Prostaglandins / Q000096:biosynthesis*; D011458:Prostaglandins E / Q000097:blood; D011460:Prostaglandins F / Q000097:blood; D011817:Rabbits
D006063:Chorionic Gonadotropin; D004967:Estrogens; D009712:Nucleotides, Cyclic; D011453:Prostaglandins; D011458:Prostaglandins E; D011460:Prostaglandins F; D000242:Cyclic AMP; D006152:Cyclic GMP