A new variety of hereditary sensory neuropathy.
A pedigree with a new form of hereditary sensory neuropathy is described. Ataxia and scoliosis rather than loss of pain and ulcerating acropathy are the principal clinical feature. Analysis of the pedigree suggests a dominant mode of transmission with variable age of onset and perhaps reduced penetrance.
D001259:Ataxia; D003638:Deafness; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D009431:Neural Conduction; D010375:Pedigree; D010523:Peripheral Nervous System Diseases / Q000235:genetics* / Q000503:physiopathology; D012306:Risk; D012600:Scoliosis; D012677:Sensation