[Investigations concerning the evidence of herpes simplex virus type 2 (HSV-2) antibodies in patients with carcinoma of the cervix (author's transl)].
The neutralizing antibodies to HSV-1 and HSV-2 were determined in the sera of 128 patients. Infection was detectable in nearly 100% of the cases in each of the three investigated groups (patients with carcinoma of the cervix, female patients with chronic recurrent HSV infection in the genital area and a control group without and history of HSV infection). The percentage of patients displaying HSV-2 antibodies in the group with carcinoma of the cervix (38%) is significantly higher than in the control group (12%). The results are compared with the findings of other authors and the possible causal significance of HSV in carcinogenesis is discussed.
D000328:Adult; D000368:Aged; D000818:Animals; D000914:Antibodies, Viral / Q000302:isolation & purification*; D000917:Antibody Formation; D002417:Cattle; D005260:Female; D006561:Herpes Simplex / Q000276:immunology; D006801:Humans; D008875:Middle Aged; D009500:Neutralization Tests; D012008:Recurrence; D018139:Simplexvirus / Q000276:immunology*; D002583:Uterine Cervical Neoplasms / Q000276:immunology* / Q000382:microbiology
D000914:Antibodies, Viral
Untersuchungen zum Nachweis von Herpes-simplex-Virus-Typ-2-(HSV-2-)Antikörpern bei Zervixharzinompatientinnen