Dual action of double-stranded RNA inhibiting protein synthesis in extracts of interferon-treated mouse L cells. Translation is impaired at the level of initiation and by mRNA degradation.
D007372:Interferons / Q000494:pharmacology*; D007739:L Cells / Q000378:metabolism*; D007930:Leucine / Q000378:metabolism; D008574:Mengovirus; D008715:Methionine / Q000378:metabolism; D010442:Peptide Chain Initiation, Translational; D014176:Protein Biosynthesis; D011506:Proteins / Q000494:pharmacology*; D012313:RNA / Q000494:pharmacology*; D012333:RNA, Messenger / Q000378:metabolism*; D012343:RNA, Transfer / Q000378:metabolism; D012367:RNA, Viral / Q000378:metabolism; D012270:Ribosomes / Q000378:metabolism
D011506:Proteins; D012333:RNA, Messenger; D012367:RNA, Viral; D012313:RNA; D007372:Interferons; D012343:RNA, Transfer; D008715:Methionine; D007930:Leucine