Prolyl hydroxylase and collagen biosynthesis in rat liver following varying degrees of partial hepatectomy.
Prolyl hydroxylase activity and collagen biosynthesis have been measured at intervals following 2 extents of hepatic resection in rats. Prolyl hydroxylase activity is validated as a measure of collagen biosynthesis. The levels rise to a peak at 72 h and thereafter decline. The implications for the process of liver regeneration are discussed.
D000818:Animals; D003094:Collagen / Q000096:biosynthesis*; D006498:Hepatectomy; D008099:Liver / Q000378:metabolism*; D008115:Liver Regeneration; D008297:Male; D009929:Organ Size; D011393:Procollagen-Proline Dioxygenase / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D003094:Collagen; D011393:Procollagen-Proline Dioxygenase