Gelatin neutralization of the inhibitory effect of sodium polyanethol sulfonate on Neisseria meningitidis in blood culture media.
The inhibitory effect of sodium polyanethol sulfonate (0.05%) upon growth of Neisseria meningitidis was found to be neutralized by adding gelatin (l.1%) to the growth medium. The neutralizing effect was demonstrated in solid medium, as well as in nutrient broth for blood cultures. The findings parallel those of Wilkins and West (6) regarding gelatin neutralization of the inhibitory effect of sodium polyanethol sulfonate on Peptostreptococcus anaerobius.
D001557:Benzenesulfonates / Q000037:antagonists & inhibitors*; D001769:Blood; D003470:Culture Media; D005780:Gelatin / Q000494:pharmacology*; D009345:Neisseria meningitidis / Q000187:drug effects* / Q000254:growth & development; D011074:Polyanetholesulfonate / Q000037:antagonists & inhibitors*
D001557:Benzenesulfonates; D003470:Culture Media; D011074:Polyanetholesulfonate; D005780:Gelatin