[Diagnosis of primary hypercholesteremia--a classification of genetic factors as causes for myocardial infarct].
Cultvated lymphocytes of patients with myocardial infarction with a primary hypercholesterolaemia as well as of unconspicuous control persons take up LDL-cholesterol labelled by 125iodine. Here is evident that lymphocytes of patients with a primary hypercholesterolaemia may incorporate significantly less LDL-cholesterol than healthy control persons. Supplementing the serum lipid determinations and the lipid electrophoresis the described radiochemical investigations at the model of lymphocytes make possible a biochemically exact diagnosis of the primary hypercholesterolaemia and thus an evident genetic analysis of the patients with infarctions.
D000293:Adolescent; D000328:Adult; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000235:genetics*; D008077:Lipoproteins, LDL / Q000097:blood; D008213:Lymphocyte Activation; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology*
D008077:Lipoproteins, LDL; D002784:Cholesterol
Zur Diagnostik der primären Hypercholesterolämie--Ein Beitrag zur Einordnung genetischer Faktoren in den Ursachenkomplex des Herzinfarktes.