Evidence that a precursor glycoprotein is cleaved to yield the major glycoprotein of avian tumor virus.
A glycoprotein designated pr90, which is recognized by anti-gp85 serum, is present in lysates of pulse-labeled transformed cells. Under chase conditions, a reduction in the level of labeled pr90 is observed concomitant with the appearance of labeled, cell-associated viral glycoprotein.
D001358:Avian Sarcoma Viruses / Q000276:immunology / Q000378:metabolism*; D002471:Cell Transformation, Neoplastic; D046508:Culture Techniques; D006023:Glycoproteins / Q000096:biosynthesis* / Q000276:immunology / Q000378:metabolism; D011498:Protein Precursors / Q000276:immunology / Q000378:metabolism*; D014764:Viral Proteins / Q000096:biosynthesis* / Q000276:immunology / Q000378:metabolism
D006023:Glycoproteins; D011498:Protein Precursors; D014764:Viral Proteins