Artifactual depression of serum glutamic oxaloacetic transaminase by metronidazole.
Eighteen patients developed abnormally low serum glutamic oxaloacetic transaminase values during metronidazole therapy. Metronidazole absorbs at 340 nm, simulating reduced nicotinamide adenine dinucleotide, which is the final colorimetric product of the serum glutamic oxaloacetic transaminase assay.
D001219:Aspartate Aminotransferases / Q000037:antagonists & inhibitors* / Q000097:blood; D006801:Humans; D008722:Methods; D008795:Metronidazole / Q000494:pharmacology*; D009243:NAD / Q000032:analysis; D013056:Spectrophotometry, Ultraviolet
D009243:NAD; D008795:Metronidazole; D001219:Aspartate Aminotransferases