Polysomes and polysomal mRNAs in SV40-infected CV-1 cells. In vivo observations.
SV40-specific polysomes are relatively larger than host polysomes. Both 16 S and 19 S virus-specific late mRNAs are found associated with these polysomes and they are present in a ratio of approximately 2 : 1. The rates at which these virus-specific mRNAs are translated are the same, so that the relative amounts of virus-specific polypeptides synthesized in the virus-infected cells is determined by the relative amounts of 16 S and 19 S mRNAs coding for them.
D002460:Cell Line; D005814:Genes, Viral; D008970:Molecular Weight; D011132:Polyribosomes / Q000378:metabolism*; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics* / Q000378:metabolism; D013539:Simian virus 40 / Q000235:genetics* / Q000378:metabolism; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000235:genetics; D014779:Virus Replication
D012333:RNA, Messenger; D014764:Viral Proteins