Mononuclear cell fraction carrying Herpesvirus saimiri in persistently infected squirrel monkeys.
Circulating lymphocytes from squirrel monkeys persistently infected with Herpesvirus saimiri (HVS) were separated into B- and T-lymphocyte fractions by a rosette-enrichment technique. HVS was isolated only from lymphocyte fractions forming rosettes or from unseparated lymphocytes; this indicated that T-lymphocytes were the target cells for HVS in the natural host, squirrel monkeys.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology / Q000382:microbiology; D002462:Cell Membrane / Q000382:microbiology; D002478:Cells, Cultured; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D000882:Haplorhini; D006564:Herpesviridae / Q000302:isolation & purification*; D006566:Herpesviridae Infections / Q000382:microbiology*; D006567:Herpesvirus 2, Saimiriine / Q000302:isolation & purification*; D008297:Male; D012453:Saimiri; D013045:Species Specificity; D013601:T-Lymphocytes / Q000276:immunology / Q000382:microbiology*