title: Identification and study of a poxvirus isolated from wild rodents in Turkmenia.
abstract: A new poxvirus was isolated in 1974 from the kidney of a wild big gerbil (Rhombomys opimus) caught in Turkmenia, where these gerbils are wide-spread. The virus resembles cowpox virus and is markedly different from the virus of infectious ectromelia, the best-known poxvirus of rodents. The new virus is apparently identical to other poxvirus isolates made from white rats and Felidae in the Moscow Zoo. Experimental inoculation of the natural hosts--big gerbils and yellow susliks (Citellus fulvus)--produced a severe infection with a high mortality rate. Trnasmission of virus to uninoculated cage mates was shown to occur. Virus persisted in convalescent animals and was present in urine 3 weeks after inoculation and in kidney and testis for at least 5 weeks after inoculation. The role of rodents as natural hosts of poxviruses is discussed.
mesh_terms: D000828:Animal Population Groups / Q000382:microbiology*; D000818:Animals; D000835:Animals, Wild / Q000382:microbiology*; D004481:Ectromelia virus / Q000276:immunology; D005849:Gerbillinae / Q000382:microbiology*; D007668:Kidney / Q000382:microbiology; D051379:Mice; D011212:Poxviridae / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity; D011213:Poxviridae Infections / Q000635:transmission; D011817:Rabbits; D051381:Rats; D014423:Turkmenistan; D014616:Vaccinia virus / Q000276:immunology