[Adenylate cyclase system and its interrelation with muscle function].
The article deals with the data of the recent years on localization, structural organization and function of the adenylate cyclase system enzymes. They are mainly membrane-linked enzymes responsible for perception, transformation and transmission of signals of nervous and humoral systems from the cell surface to its internal part, right up the genetic apparatus. The enzymes are characterized catalyzing formation and transformation of cAMP-adenylate cyclase, phosphodisterase and enzymes by means of which intracellular metabolism is regulated with participation of cAMP-protein kinases and phosphoproteinphosphatases. The data are systematized as to possible interrelation of the adenylate cyclatase system function with calcium ion exchange. Attention is concentrated on the system possible role in the transport of this important cation, particularly in ensuring the function of the organism contractile systems.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism; D009132:Muscles / Q000201:enzymology / Q000502:physiology*; D009469:Neuromuscular Junction / Q000502:physiology; D010749:Phosphoprotein Phosphatases / Q000378:metabolism; D011494:Protein Kinases / Q000378:metabolism
D000242:Cyclic AMP; D011494:Protein Kinases; D010749:Phosphoprotein Phosphatases; D000262:Adenylyl Cyclases
Adenilattsiklaznaia sistema i ee vzaimosviaz' s funktsieĭ myshts.