title: Effect of Clostridium toxoids, especially of Clostridium perfringens toxoid, on mouse transplanted tumors.
abstract: The antitumor activities of toxoids of Clostridium perfringens, C. nouyi, C. septicum, and C. tetani were tested against sarcoma-180 and Ehrlich carcinoma. Among them, C. perfringens toxoid showed a high antitumor activity against the growth of the implanted sarcoma-180 ascites form. The results of the inhibiting effect of C. perfringens toxoid on Nakahara-Tokuzen-Fukuoka (NTF) reticulum cell sarcoma and methylcholanthrene-induced fibrosarcoma were also described.
mesh_terms: D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000628:therapy; D003013:Clostridium; D003016:Clostridium perfringens; D003017:Clostridium tetani; D005260:Female; D005354:Fibrosarcoma / Q000628:therapy; D007167:Immunotherapy; D016403:Lymphoma, Large B-Cell, Diffuse / Q000628:therapy; D051379:Mice; D008813:Mice, Inbred ICR; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000628:therapy*; D012510:Sarcoma 180 / Q000628:therapy; D012513:Sarcoma, Experimental / Q000628:therapy; D014121:Toxoids / Q000302:isolation & purification
chemical_list: D014121:Toxoids