Dependence of yeast sporulation on mitochondrial protein synthesis.
Sporulation in diploid Saccharomyces cerevisiae is not dependent on continued protein synthesis in the mitochondria. Using chloramphenicol, it is shown that proteins essential for respiration and sporulation are synthesized in mitochondria early during growth in a presporulation medium.
D002701:Chloramphenicol / Q000494:pharmacology; D003513:Cycloheximide / Q000494:pharmacology; D004171:Diploidy; D003576:Electron Transport Complex IV / Q000378:metabolism; D005656:Fungal Proteins / Q000096:biosynthesis*; D008291:Malate Dehydrogenase / Q000378:metabolism; D008928:Mitochondria / Q000201:enzymology / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000254:growth & development* / Q000378:metabolism; D013172:Spores, Fungal / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism
D005656:Fungal Proteins; D002701:Chloramphenicol; D003513:Cycloheximide; D008291:Malate Dehydrogenase; D003576:Electron Transport Complex IV