[Test of an attenuated viral strain of TGE as a vaccine].
A live vaccine was produced using a local strain P of the virus of the transmissive gastroenteritis, arrenuated in cell cultures. The vaccinated pregnant sows had high-titer serum and colostrum virus-neutralizing antibodies. In the first days following farrowing there were in the colostrum ummunoglobulins of the Igg class that prevailed, however, IgA and IgM proved more effective in the virus-neutralizing test. Newborn pigs acquired passive immunity at about the 24th hour after the intake of colostrum. They withstood a challenge with a virulent virus.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D003126:Colostrum / Q000276:immunology; D003332:Coronaviridae / Q000276:immunology*; D004353:Drug Evaluation, Preclinical / Q000662:veterinary; D005260:Female; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008892:Milk / Q000276:immunology; D009500:Neutralization Tests; D011247:Pregnancy; D013552:Swine / Q000276:immunology; D005760:Transmissible gastroenteritis virus / Q000276:immunology*; D014611:Vaccination / Q000662:veterinary; D014613:Vaccines, Attenuated / Q000276:immunology*; D014765:Viral Vaccines / Q000276:immunology*
D000914:Antibodies, Viral; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D014613:Vaccines, Attenuated; D014765:Viral Vaccines
Izpitvane atenuiran virusen shtam na TGE kato vaksina.