Mercury complexes of thionicotinamide adenine dinucleotide.
One-to-one mercury complexes of thionicotinamide adenine dinucleotide (TNAD+) were prepared by using HgSO4 and Hg(CH3 COO-)2. Optical absorption spectroscopy indicated that the mercury probably binds to the TNAD+ through the thio-keto group on the pyridine ring. X-ray diffraction patterns of crystals of mitochondrial malate dehydrogenase soaked in solution containing TNAD+ . mercury complex indicated binding and the X-ray intensity differences are different from mercurials alone.
D055598:Chemical Phenomena; D002621:Chemistry; D008291:Malate Dehydrogenase; D008628:Mercury; D009243:NAD / Q000031:analogs & derivatives*; D011485:Protein Binding; D013056:Spectrophotometry, Ultraviolet; D014961:X-Ray Diffraction
D009243:NAD; C003451:thionicotinamide adenine dinucleotide; D008291:Malate Dehydrogenase; D008628:Mercury