[Use of the passive hemagglutination test for the purpose of determining antibody levels following animal immunization with Cl. perfringens toxoid].
Data are presented on the study of possibilities of the application of the passive hemagglutination test for titration of the blood sera of mice, guinea pigs and rabbits immunized with Cl. perfringens toxoid. A diagnostic agent obtained by the sensitization of formalin- and tannin-treated sheep erythrocytes with the serologically pure toxoid, and homologous sera (as standard) were used in this test. A high immune response of BALB/c and C3H mice to the Cl. perfringens toxoid permits to suggest inbred mice as a model for the immunological and immunogenetic studies connected with this toxoid.
D000818:Animals; D000992:Antitoxins / Q000032:analysis*; D003015:Clostridium Infections / Q000517:prevention & control*; D003016:Clostridium perfringens; D006168:Guinea Pigs; D006386:Hemagglutination Tests; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D011817:Rabbits; D014121:Toxoids
D000992:Antitoxins; D014121:Toxoids
O primenenii reaktsii passivnoĭ gemaggliutinatsii s tsel'iu opredeleniia urovnia antitel pri immunizatsii zhivotnykh anatoksinom Cl. perfringens