Growth hormone secretion in Addison's disease.
Growth hormone secretion has been evaluated in patients with Addison's disease given T.R.H., A.C.T.H. or Glucagon i.v., or L-DOPA p.o. In those with the idiopathic, auto-immune variety the mean response to glucagon and L-DOPA was reduced when compared with that documented for patients in whom tuberculosis caused the lesion. Growth hormone plasma concentrations barely changed after T.R.H. and A.C.T.H., irrespective of the aetiology of the disease.
D000224:Addison Disease / Q000209:etiology / Q000503:physiopathology*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D005260:Female; D005934:Glucagon / Q000494:pharmacology; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D007980:Levodopa / Q000494:pharmacology; D008297:Male; D012636:Secretory Rate / Q000187:drug effects
D007980:Levodopa; D000324:Adrenocorticotropic Hormone; D013006:Growth Hormone; D005934:Glucagon