title: [Relationship between the limbic system and gonadal function. 2. Quantifiable prepuberal differentiation of medial cortical amygdaloid nuclei].
abstract: In juvenile female rats beteen the 21st and 26th days of age, the neurons of the medial and cortical amygdaloid nuclei undergo a highly significant karyovolumetrically measurable activation which, however, partially declines almost immediately. Such prepuberal variation of activity was found to be correlated with age-dependent effects of direct interventions with these nuclear regions upon the hypothalamy-pituitary-gonadal axis, e.g. implantation of oestradiol benzoate, stimulation or lesioning. This basically, is a quantitatibe-morphological confirmation of an assumption that had been derived earlier from experimental studies, according to which the mediocortical part of the amygdala undergoes in the prepuberal period a functional muteration or differentiation which is specific and related to puberty and gonadal functions (Döcke, 1976a, b; Döcke et al., 1976).
mesh_terms: D000375:Aging; D000679:Amygdala / Q000502:physiology*; D000818:Animals; D002454:Cell Differentiation; D002540:Cerebral Cortex / Q000502:physiology*; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D006066:Gonads / Q000502:physiology*; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects; D008032:Limbic System / Q000502:physiology*; D051381:Rats; D012741:Sexual Maturation
chemical_list: D004958:Estradiol
vernacular_title: Zur Frage der Beziehung des limbischen Systems zur Gonadenfunktion. 2. Mitteilung: Quantifizierbare präpuberale Differenzierung der Nuclei amygdaloidei medialis und corticalis.