title: [Effect of somatotropic hormone on certain indices related to carbohydrate and fat metabolism in sheep].
abstract: Investigated was the effect of the somatotropic hormone (STH) at doses of 0.3 mg/kg and 1 mg/kg liveweight on the amount of insulin, glucose, and free fatty acids (FFA) in the serum up to the 12th hour following treatment. The activity of glucose-6-phosphatase and the amount of glycogen were studied in tissue samples taken through biopsy of the liver at the 2nd, 4th, 6th, and 8th hour after treatment with STH. The content of blood sugar decreased, and that of insulin increased in the course of one hour following treatment. The values shown by FFA first dropped (at the end of the 1st hour), and then rose by the 6th hour after treatment. The amount of glycogen and the activity of glucose-6-phosphatase increased at the 6th hour following treatment with STH. The variations shown by the investigated indices depend on the size of the STH doses.
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D050260:Carbohydrate Metabolism; D004305:Dose-Response Relationship, Drug; D005215:Fasting; D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D005952:Glucose-6-Phosphatase / Q000378:metabolism; D013006:Growth Hormone / Q000494:pharmacology*; D007328:Insulin / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D008112:Liver Glycogen / Q000378:metabolism; D012756:Sheep / Q000378:metabolism*; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D008112:Liver Glycogen; D013006:Growth Hormone; D005952:Glucose-6-Phosphatase
vernacular_title: Vliianie na somatotropniia khormon vurkhu niakoi pokazateli, svurzani s vuglekhidratniia i mastniia obmen pri ovtse