Studies on histones and nuclear phosphoproteins of rat liver and Morris hepatoma.
1. The chemical composition of chromatins obtained from Buffalo rat liver and Morris hepatoma strain 5123 was investigated. 2. The presence of an additional subfraction within the very lysine-rich histone (fl) was states in both kinds of tissues. It amounted to about 8% and 5% of fl in rat liver and Morris hepatoma, respectively. 3. Nuclear phosphoproteins (phenol-soluble) from normal and tumour tissues in polyacrylamide gel in SDS showed some qualitative differences in the range of molecular weights of about 40 000 - 70 000 and over 100 000 daltons.
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000032:analysis*; D002843:Chromatin / Q000032:analysis; D004591:Electrophoresis, Polyacrylamide Gel; D006657:Histones / Q000032:analysis*; D008099:Liver / Q000032:analysis* / Q000648:ultrastructure; D008113:Liver Neoplasms; D008970:Molecular Weight; D009363:Neoplasm Proteins / Q000032:analysis*; D009374:Neoplasms, Experimental / Q000032:analysis; D009698:Nucleoproteins / Q000032:analysis*; D010750:Phosphoproteins / Q000032:analysis; D051381:Rats
D002843:Chromatin; D006657:Histones; D009363:Neoplasm Proteins; D009698:Nucleoproteins; D010750:Phosphoproteins