title: Nomenclature for gliomas.
abstract: Gliomas, derived from astrocytes, oligodendroglia, or ependyma, are each united into a continuum by a graduation of anaplasia. Neoplasms originate at all levels of each continuum; subsequently, some move along its declivity. Conversely, neuroblastic tumors may differentiate, whereas concomitantly in the same lesion, the glial stroma may dedifferentiate. Anaplastic glia, as in a glioblastoma multiforme, can initiate malignant transformation in alien cells.
mesh_terms: D000368:Aged; D000708:Anaplasia / Q000473:pathology; D001254:Astrocytoma / Q000145:classification / Q000473:pathology; D001932:Brain Neoplasms / Q000145:classification* / Q000473:pathology; D002648:Child; D005260:Female; D005909:Glioblastoma / Q000145:classification / Q000473:pathology; D005910:Glioma / Q000145:classification* / Q000473:pathology; D006801:Humans; D008297:Male; D009626:Terminology as Topic