title: [Use of prodigiozan for preventing acute respiratory viral diseases in a children's collective].
abstract: The epidemiological efficacy of 0.02 per cent solution of prodigiosan, a bacterial polysaccharide was used for the treatment of children in an area with acute respiratory infections, such as influenza and parainfluenza. The drug was administered intranasally by means of a dosing sprayer in the amounts of 0.2 ml once in 4 days for 4 months. Among the children treated with prodigiosan the rate of the acute respiratory viral infections was 2 times lower and the average duration of the disease was 2.4 times lower as compared to the control group. After 4 months of the drug use the average value of the "skin autoflora" test was much lower than that in the control group which testified to an increase in the non-specific immunobiological reactivity of the children under the effect of prodigiosan.
mesh_terms: D000208:Acute Disease; D000281:Administration, Intranasal; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D006801:Humans; D007251:Influenza, Human / Q000517:prevention & control; D008070:Lipopolysaccharides / Q000627:therapeutic use*; D018184:Paramyxoviridae Infections / Q000517:prevention & control; D011135:Polysaccharides, Bacterial / Q000627:therapeutic use*; D012141:Respiratory Tract Infections / Q000517:prevention & control*; D012706:Serratia marcescens; D012867:Skin / Q000382:microbiology; D012882:Skin Tests; D014777:Virus Diseases / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents; D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial
vernacular_title: Primenenie prodigiozana dlia profilaktiki ostrykh respiratornykh virusnykh zabolevaniĭ v detskom kollektive.