Formaldehyde-ozone-induced fluorescence in pituitary ACTH cells: effect of adrenalectomy.
ACTH and MSH cells of the pituitary are rich in peptides with NH2-terminaltryptophan, as revealed by fluorescence histochemistry. Adrenalectomy stimulates the ACTH cells but not the MSH cells. As a result, ACTH as well as tryptophyl-peptides disappear from the ACTH cells but not from the MSH cells. It is concluded that the tryptophyl-peptides are stored together with the respective hormone in the ACTH and MSH cells and that tryptophyl-peptides in the ACTH cells are released together with the hormone.
D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone; D000818:Animals; D006224:Cricetinae; D005453:Fluorescence; D005557:Formaldehyde; D009074:Melanocyte-Stimulating Hormones; D010126:Ozone; D010902:Pituitary Gland / Q000166:cytology*
D005557:Formaldehyde; D010126:Ozone; D000324:Adrenocorticotropic Hormone; D009074:Melanocyte-Stimulating Hormones