title: Osteosclerotic myeloma.
abstract: A 49-year-old man with an osteosclerotic lesion of a thoracic vertebra had peripheral neuropathy, lymphadenopathy, and elevated serum alkaline phosphatase and monoclonal immunoglobulin levels in the cerebrospinal fluid. These findings, not usually seen in ""classical'' myeloma, have been noted in different combinations in the osteosclerotic variety.
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis / Q000134:cerebrospinal fluid; D008206:Lymphatic Diseases / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000201:enzymology / Q000473:pathology*; D010026:Osteosclerosis / Q000473:pathology*; D010523:Peripheral Nervous System Diseases / Q000473:pathology; D013904:Thoracic Vertebrae / Q000473:pathology
chemical_list: D007074:Immunoglobulin G; D000469:Alkaline Phosphatase