Demyelinating peripheral neuropathy in a guinea hen associated with subacute lead intoxication.
In mammalian species lead acts primarily as a neurotoxin. Lead poisoning is common in avian species but lesions in the nervous system have not been associated with it. This paper describes a peripheral neuropathy with fragmentation and segmental demyelination of fibers in the sciatic nerves of an adult guinea hen (Numida meleagris) which died of lead poisoning.
D000818:Animals; D003711:Demyelinating Diseases / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D005260:Female; D007855:Lead Poisoning / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D011200:Poultry; D011201:Poultry Diseases / Q000139:chemically induced* / Q000473:pathology