Esophageal complications in the treatment of oat cell carcinoma with combined irradiation and chemotherapy.
A case of esophageal stenosis was noted in a patient treated with a combination of irradiation and chemotherapy for oat cell carcinoma. Review of the entire series of 22 patients revealed an unusually high rate (8/22) of esophagitis. These complications are discussed in relation to timing radiation dose and multidrug chemotherapy
D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D003520:Cyclophosphamide / Q000009:adverse effects / Q000627:therapeutic use; D004317:Doxorubicin / Q000009:adverse effects / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000009:adverse effects*; D004940:Esophageal Stenosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D008297:Male; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D011878:Radiotherapy / Q000009:adverse effects*; D014750:Vincristine / Q000009:adverse effects / Q000627:therapeutic use
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D008727:Methotrexate