[Initial trial of a new test for the evaluation of hepatocellular function: the TMB test].
The oral administration of 400 mg of trimethoxy 1-3-5-benzene or T.M.B. is normally followed by a high urinary excretion of dimethoxy, 1, 3, hydroxy 5 benzene and other metabolites mainly in the form of conjugates. Urinary excretion during the first 3 hours is strongly reduced in liver disease. By a simple blind test we showed that the test is positive in subclinical and laboratory-negative liver failure.
D000328:Adult; D000368:Aged; D000840:Anisoles; D005260:Female; D006139:Guaiacol / Q000031:analogs & derivatives / Q000652:urine; D006801:Humans; D008107:Liver Diseases / Q000652:urine; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged
D000840:Anisoles; D006139:Guaiacol
Premiers essais d'un nouveau test d'évaluation du fonctionnement hépatocellulaire: le test au TMB.