[Study of smallpox vaccine virus distribution in the body of rabbits following oral immunization].
Virological and immunofluorescent methods were applied to the study of the distribution of the smallpox vaccine virus in the organs and tissues of rabbits immunized orally. It appeared that the vaccinal process developed with a predominant localization of the antigen in the regional (in respect to the site of administration) lymph nodes; the virus was revealed in the cell cytoplasm.
D000284:Administration, Oral; D000818:Animals; D000956:Antigens, Viral / Q000302:isolation & purification; D003593:Cytoplasm / Q000382:microbiology; D008198:Lymph Nodes / Q000382:microbiology; D009928:Organ Specificity; D011817:Rabbits; D012900:Smallpox Vaccine / Q000008:administration & dosage*; D012901:Variola virus / Q000276:immunology / Q000302:isolation & purification*
D000956:Antigens, Viral; D012900:Smallpox Vaccine
Izuchenie raspredeleniia v organizme virusa ospovaktsiny pri oral'noĭ immunizatsii krolikov