title: EMS-induced reversion studies in the white locus of Drosophila melanogaster.
abstract: 5 white-locus mutants of Drosophila melanogaster, respresenting 5 different sub-sites, were treated with EMS and tested for reversion to wild-type. 4 of them were genuine mutants and one was not. Moreover, the ability of the 4 mutants to revert to wild-type differed from one another which therefore reflects a qualitatively distinct alteration in the genetic material delimited by each mutant.
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D004331:Drosophila melanogaster / Q000187:drug effects / Q000235:genetics; D005020:Ethyl Methanesulfonate / Q000494:pharmacology*; D005127:Eye Color; D005260:Female; D008297:Male; D008698:Mesylates / Q000494:pharmacology*; D009154:Mutation / Q000187:drug effects*; D013489:Suppression, Genetic
chemical_list: D008698:Mesylates; D005020:Ethyl Methanesulfonate