[Demonstration of specific receptor sites of 3, 5, 3'-triiodo-L-thyronine on isolated rat hepatocytes].
The polarographic respiration studies of isolated liver cells from normal and thyroidectomised rats show that oxygen consumption rate is decreased by 40% after thyroidectomy. The number of specific binding sites estimated with 125I labelled T3 experiments, is about 130 per cell.
D000818:Animals; D001665:Binding Sites; D066298:In Vitro Techniques; D007457:Iodine Radioisotopes; D008099:Liver / Q000166:cytology / Q000187:drug effects*; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats; D011956:Receptors, Cell Surface; D013965:Thyroidectomy; D014284:Triiodothyronine / Q000494:pharmacology*
D007457:Iodine Radioisotopes; D011956:Receptors, Cell Surface; D014284:Triiodothyronine
Mise en évidence de sites récepteurs spécifiques de la 3, 5, 3'-triiodo-L-thyronine sur les hépatocytes isolés de rat