[Non-addictive properties of tiapride (1347)].
Possible addiction to tiapride was sought in a 10 kg Beagle dog and an ordinary 12 kg dog using the substitution method suggested by J.J. Deglarez. Tiapride at a dose of 30 mg/kg was not able to interrupt the state of hyperexcitability triggered off by sudden morphine withdrawal. On may consider that tiapride is completely lacking in addictive properties.
D000818:Animals; D001549:Benzamides / Q000494:pharmacology*; D004285:Dogs; D006801:Humans; D009021:Morphine Dependence; D013375:Substance Withdrawal Syndrome; D019966:Substance-Related Disorders; D014149:Tranquilizing Agents / Q000494:pharmacology*
D001549:Benzamides; D014149:Tranquilizing Agents
Rapport au sujet des propriétés non toxicomanogènes du tiapride (1347).