Effect of protein deficiency on absorption, transport and distribution of alpha-tocopherol in the rat.
The absorption, transport and distribution of alpha-[3H]tocopherol were greatly decreased in protein deficiency. This was reflected in the subcellular distribution of alpha-[3H]tocopherol in livers of protein-deficient rats. The ratio, bound:free for alpha-[3H]tocopherol, also decreased in both serum and liver cytosol. After protein refeeding, absorption, transport and distribution patterns of alpha-[3H]tocopherol for the protein-deficient rats were restored to patterns similar to those of control animals.
D000818:Animals; D001693:Biological Transport, Active; D004044:Dietary Proteins / Q000378:metabolism; D007408:Intestinal Absorption; D008079:Lipoproteins, VLDL / Q000378:metabolism; D008099:Liver / Q000166:cytology / Q000378:metabolism; D008297:Male; D011485:Protein Binding; D011488:Protein Deficiency / Q000378:metabolism*; D051381:Rats; D013347:Subcellular Fractions / Q000378:metabolism; D014810:Vitamin E / Q000378:metabolism*
D004044:Dietary Proteins; D008079:Lipoproteins, VLDL; D014810:Vitamin E