title: Detection of Mason-Pfizer monkey virus infection by syncytia formation of human cells doubly transformed by Rous sarcoma virus and simian virus 40.
abstract: Human cells doubly transformed by Rous sarcoma virus and SV40 (RSb cells) formed syncytia by cocultivation with Mason-Pfizer monkey virus (MPMV)-producing cells. This cell fusion was blocked by anti-MPMV serum indicating that the phenomenon is MPMV specific. The RSb cells were successfully used for MPMV infectivity assay in the same manner as KC cells.
mesh_terms: D000914:Antibodies, Viral; D001358:Avian Sarcoma Viruses; D002459:Cell Fusion; D002460:Cell Line; D002472:Cell Transformation, Viral; D012328:RNA Viruses / Q000254:growth & development* / Q000276:immunology; D013539:Simian virus 40
chemical_list: D000914:Antibodies, Viral