title: The initiation region of the SV40 VP1 gene.
abstract: The sequence of 15 nucleotides located at the 5' terminus of the plus strand of the SV40 Hind K fragment has been determined as (5') A-G-C-T-T-A-T-G-A-A-G-A-T-G-G (3'). The 3' on OH terminal G of this segment is part of the G-C-C codeword for the N terminal alanine of the VP1 protein. This region therefore presumably corresponds to a ribosome binding site on the 16S late mRNA. Complementarily to the 3' OH of eucaryotic 18S ribosomal RNA and homology with the BMV coat ribosome binding site are discussed.
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis*; D001483:Base Sequence; D001665:Binding Sites; D003062:Codon; D004279:DNA, Viral / Q000032:analysis*; D005796:Genes; D012333:RNA, Messenger / Q000378:metabolism; D012367:RNA, Viral / Q000378:metabolism; D012270:Ribosomes / Q000378:metabolism; D013539:Simian virus 40
chemical_list: D001426:Bacterial Proteins; D003062:Codon; D004279:DNA, Viral; D012333:RNA, Messenger; D012367:RNA, Viral