Immunocytochemical localization of binding 'sites' for LH and hCG in preimplantation mouse embryos.
By using an immunoperoxidase antibody method, mouse blastocysts were found to bind specifically hCG and ovine LH but not FSH or the beta unit of hCG. Brown peroxidase reaction products were present in the morula and increased with the formation of the blastocoele. The LH/hCG binding 'sites' may be related to the initiation of steroidogenesis in the embryo.
D000818:Animals; D001755:Blastocyst / Q000378:metabolism; D006063:Chorionic Gonadotropin / Q000378:metabolism*; D004622:Embryo, Mammalian / Q000378:metabolism*; D047108:Embryonic Development; D005260:Female; D007124:Immunoenzyme Techniques; D007986:Luteinizing Hormone / Q000378:metabolism*; D051379:Mice; D011247:Pregnancy; D011956:Receptors, Cell Surface / Q000378:metabolism*
D006063:Chorionic Gonadotropin; D011956:Receptors, Cell Surface; D007986:Luteinizing Hormone