An ultrastructural study of eosinophilic granuloma: the Langerhans cell--its role in histogenesis and diagnosis.
An electron microscopic study of a case of eosinophilic granuloma of the mandible was performed. The fine structural similarity between the "histiocytic" cells of the lesion and epidermal Langerhans cells is discussed with regard to current theories and information on the origin of Langerhans cells and their potential role in the histogenesis of eosinophilic granuloma and other variants of histiocytosis X.
D000328:Adult; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004803:Eosinophilic Granuloma / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D004804:Eosinophils / Q000648:ultrastructure; D005260:Female; D006644:Histiocytes / Q000648:ultrastructure; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D007801:Langerhans Cells / Q000166:cytology / Q000648:ultrastructure*; D008336:Mandibular Diseases / Q000473:pathology*