The contribution of hepatic triglyceride lipase to plasma post-heparin lipolytic activity in the rat.
Plasma post-heparin lipolytic activity (PHLA) was reduced by 50% in functionally hepatectomised compared with shamoperated rats. Inhibition of PHLA by protamine sulphate was significantly increased in functionally hepatectomised compared with shamoperated rats. Hepatic triglyceride lipase contributes significantly to total plasma PHLA. Its function is not yet clear.
D000818:Animals; D003864:Depression, Chemical; D006493:Heparin; D006498:Hepatectomy; D008049:Lipase / Q000378:metabolism*; D008055:Lipids / Q000097:blood*; D008079:Lipoproteins, VLDL / Q000097:blood; D008099:Liver / Q000201:enzymology*; D008297:Male; D011479:Protamines / Q000494:pharmacology; D051381:Rats; D014280:Triglycerides
D008055:Lipids; D008079:Lipoproteins, VLDL; D011479:Protamines; D014280:Triglycerides; D006493:Heparin; D008049:Lipase