[Research on substances with antiviral activity. VIII. Benzindanoncarboxylic acids].
New derivatives (esters, amides, nitriles, amidines, thiosemicarbazones and guanylhydrazones) of 1H-benz[e]indene-2,3-dihydro-5-methyl-1-oxo-3-carboxylic acid and 1H-benz[e]indene-2,3-dihydro-7-methyl-3-oxo-1-carboxylic acid were prepared and tested for antiviral activities in vitro against vaccinia virus, HID stock and parainfluenza type 3 virus, HA-I/CR-8 stock. Four compounds (II g), (II i), (III b), (III g), showed weak activity in vitro against vaccinia virus.
D000998:Antiviral Agents / Q000138:chemical synthesis*; D002264:Carboxylic Acids / Q000138:chemical synthesis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D012106:Research; D018108:Respirovirus / Q000187:drug effects; D014616:Vaccinia virus / Q000187:drug effects
D000998:Antiviral Agents; D002264:Carboxylic Acids
Ricerche su sostanze ad attività antivirale. Nota VIII - Derivati di acidi benzindanoncarbossilici.