Somatostatin inhibits the release of acetylcholine induced electrically in the myenteric plexus.
Somatostatin inhibits the release of acetylcholine electrically induced in the myenteric plexus-longitudinal muscle of the guinea pig ileum. This effect is not mediated by opiate receptors. Tachyphylaxis to this effect of somatostatin has been observed.
D000109:Acetylcholine / Q000378:metabolism* / Q000494:pharmacology; D000818:Animals; D004558:Electric Stimulation; D006168:Guinea Pigs; D007082:Ileum; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D009197:Myenteric Plexus / Q000187:drug effects / Q000502:physiology*; D009270:Naloxone / Q000494:pharmacology; D013004:Somatostatin / Q000494:pharmacology*; D009435:Synaptic Transmission / Q000187:drug effects
D009270:Naloxone; D013004:Somatostatin; D000109:Acetylcholine