[Possible significance of hexokinase binding to mitochondrial membranes].
A magnitude of the Pasteur's effect and content of bound hexokinase were studied in various malignant and normal tissues. In all cases studied these two values were practically the same. Dynamics of changes in subcellular localization of hexokinase and the Pasteur's effect were similarly altered in liver tissue during ontogenesis. Binding hexokinase with mitochondrial membranes was assumed to be the cytophysiological mechanism for regulation of glycolytic activity by respiration.
D000818:Animals; D001665:Binding Sites; D002286:Carcinoma, Ehrlich Tumor / Q000201:enzymology*; D006528:Carcinoma, Hepatocellular / Q000201:enzymology*; D006593:Hexokinase / Q000378:metabolism*; D008113:Liver Neoplasms / Q000201:enzymology*; D051379:Mice; D008928:Mitochondria / Q000201:enzymology*
D006593:Hexokinase
O vozmozhnom znachenii sviazyvaniia geksokinazy s membranami mitokhondriĭ