Multiple buoyant densities of hepatitis A virus in cesium chloride gradients.
Hepatitis A virus (HAV) recovered from stools of human cases of hepatitis A and from stools of chimpanzees experimentally infected with HAV was shown to possess multiple buoyant densities in CsCl gradients. The greatest proportion of HAV was most frequently found at a buoyant density of 1.32-1.34 g/cm3, however, large proportions of HAV were also frequently found at higher densities, including 1.36-1.37, 1.40-1.42, and 1.45-1.48 g/cm3. These findings are consistent with the notion that HAV may be a parvovirus.
D000818:Animals; D002499:Centrifugation, Density Gradient; D004770:Enterovirus / Q000145:classification; D005243:Feces / Q000382:microbiology; D006507:Hepatovirus / Q000032:analysis* / Q000145:classification; D006801:Humans; D002679:Pan troglodytes; D010321:Parvoviridae / Q000145:classification