title: [Effect of estradiol-17 beta on the somatrotroph cells of the adenohypophysis in the newt (author's transl)].
abstract: The somatotroph cells of the female newt's adenohypophysis are characterized by PAS positive, acidophils, electron dense large inclusions (4-6 micrometer). The apparition of these inclusions has been studied in females during the puberty. A correlation between the ovary stages and apparition, number and ultrastructural aspects (paracrystalline arrangement) of the inclusions is established. Same inclusion genesis and aspects has been observed after treatment of young newt males by oestradiol-17 beta (5 mg/liter diluted in the aquarium water). It is concluded that endocrine activity of ovaries may be responsible of the inclusions occurence in the females.
mesh_terms: D000818:Animals; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008297:Male; D010053:Ovary / Q000502:physiology*; D010903:Pituitary Gland, Anterior / Q000648:ultrastructure*; D011110:Polymorphism, Genetic / Q000187:drug effects*; D012455:Salamandridae
chemical_list: D004958:Estradiol
vernacular_title: Rôle des oestrogènes dans l'apparition d'un dimorphisme sexuel des cellules somatotropes de l'hypophyse du trition Pleurodèle.