title: Collagenase is a component of the specific granules of human neutrophil leucocytes.
abstract: Azurophil and specific granules were isolated from human polymorphonuclear neutrophil leucocytes. Collagenase was almost exclusively a component of the specific granules. This finding is in contrast with the distribution of other proteolytic enzymes, which are localized in the azurophil (or lysosomal) granules.
mesh_terms: D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D003012:Microbial Collagenase / Q000378:metabolism*; D009504:Neutrophils / Q000201:enzymology* / Q000648:ultrastructure
chemical_list: D003012:Microbial Collagenase