title: Localisation on foot-and-mouth disease virus (FMDV) of an antigenic deficiency induced by passage in BHK cells.
abstract: Passage of FMDV in BHK suspended cells was confirmed to induce an antigenic deficiency on the virion. By immunodiffusion experiments with complete virus, with trypsin-treated virus and with 12S virus fraction it was shown that the induced antigenic deficiency is located on the trypsin-removable part of the virion. These results were confirmed by absorption experiments.
mesh_terms: D000818:Animals; D000956:Antigens, Viral; D005537:Aphthovirus / Q000187:drug effects / Q000276:immunology*; D002417:Cattle / Q000276:immunology; D002460:Cell Line; D006224:Cricetinae; D006168:Guinea Pigs / Q000276:immunology; D007106:Immune Sera; D005779:Immunodiffusion; D009500:Neutralization Tests; D013552:Swine / Q000276:immunology; D014357:Trypsin / Q000494:pharmacology; D014776:Virus Cultivation
chemical_list: D000956:Antigens, Viral; D007106:Immune Sera; D014357:Trypsin