Observations on the neuromuscular blocking action of alcuronium in the dog and its reversal by neostigmine.
The action of alcuronium chloride on neuromuscular transmission in the dogs was investigated by electrical and mechanical methods. The mean duration of action was 70 min. Reversal of its action was produced with atropine and neostigmine.
D000443:Alcuronium / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D004285:Dogs / Q000502:physiology*; D009388:Neostigmine / Q000494:pharmacology*; D009466:Neuromuscular Blocking Agents; D009435:Synaptic Transmission / Q000187:drug effects; D014117:Toxiferine / Q000031:analogs & derivatives*
D009466:Neuromuscular Blocking Agents; D009388:Neostigmine; D001285:Atropine; D014117:Toxiferine; D000443:Alcuronium