Glucagon effects on plasma cyclic AMP and other reactants in normals and low insulin responders.
The metabolic response to i.v. glucagon was evaluated in 11 normal individuals and 8 healthy low insulin responders. Elevations of plasma cyclic AMP and blood glucose were similar in both groups. Accordingly, no indications were seen of differing hepatic responsiveness to glucagon. In contrast, the groups differed in the course of plasma glycerol during the test.
D000273:Adipose Tissue / Q000378:metabolism; D001786:Blood Glucose / Q000032:analysis; D000242:Cyclic AMP / Q000097:blood*; D005934:Glucagon / Q000008:administration & dosage / Q000494:pharmacology*; D005951:Glucose Tolerance Test; D005990:Glycerol / Q000097:blood; D006801:Humans; D007275:Injections, Intravenous; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged
D001786:Blood Glucose; D007328:Insulin; D005934:Glucagon; D000242:Cyclic AMP; D005990:Glycerol