[Biosynthesis of cardiolipin in the rat hepatoma 27 and Jensen sarcoma].
The localization of cardiolipin biosynthesis in rat hepatoma 27 and Jensen sarcoma cells was investigated. In both tumors cardiolipin was found to be synthesized only in the mitochondria as is the case in normal rat liver. It is concluded that the occurrence of cardiolipin in the microsomes of the tumor cells may be connected with a transmembrane exchange of phospholipids in vivo.
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000378:metabolism*; D002308:Cardiolipins / Q000096:biosynthesis*; D008113:Liver Neoplasms / Q000378:metabolism*; D008861:Microsomes / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism; D009374:Neoplasms, Experimental / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D051381:Rats; D012513:Sarcoma, Experimental / Q000378:metabolism*
D002308:Cardiolipins; D010743:Phospholipids
Biosintez kardiolipina v gepatome 27 i sarkome Iensena krys