[Modification of chromosome aberrations caused by kilham virus in rat embryo cells].
Mutagenic effect of Kilham virus on the frequency of chromosome aberrations in the cells of primary and continous rat embryo cultures and the modification effect of cadmium salt on the mutagenic potential of this virus was studied. The frequency of chromosome aberrations increased in the primary rat embryo culture after Kilham virus enfection. Rat embryo culture chronically infected with Kilham virus did not differ from control continuous cells in the frequency level of chromosome aberrations. Isertion of cadmium in the process of cultivation increased the mutagenic effect of kilham virus in the primary rat embryo culture.
D000818:Animals; D002104:Cadmium / Q000494:pharmacology; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D066298:In Vitro Techniques; D008938:Mitosis; D010321:Parvoviridae / Q000187:drug effects; D017992:Parvovirus / Q000187:drug effects*; D051381:Rats
D002104:Cadmium
Modifikatsiia khromosomnykh aberratsiĭ pod deĭstiviem virusa kilkhéma v kletkakh krysinykh émbrionov.