Experimental infection of rabbits with the virus of infectious bovine rhinotracheitis.
Adult and newborn rabbits were infected with the LA strain of infectious bovine rhinotracheitis virus. Adult rabbits developed only mild, self-limiting conjunctivitis, but had microscopic inflammatory foci in the liver and adrenal glands. Newborn rabbits developed a severe, sometimes fatal, generalized infection with focal and diffuse necrosis of the liver and adrenal glands.
D000307:Adrenal Gland Diseases / Q000209:etiology; D000818:Animals; D000831:Animals, Newborn / Q000382:microbiology*; D003231:Conjunctivitis / Q000209:etiology; D004195:Disease Models, Animal; D005260:Female; D007242:Herpesvirus 1, Bovine / Q000472:pathogenicity*; D007249:Inflammation; D008099:Liver / Q000648:ultrastructure; D008107:Liver Diseases / Q000209:etiology; D009336:Necrosis; D011817:Rabbits