title: Effect of agonist-antagonist interaction on the development of tolerance and dependence.
mesh_terms: D000698:Analgesia; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004347:Drug Interactions; D004361:Drug Tolerance; D006801:Humans; D008297:Male; D009020:Morphine / Q000008:administration & dosage / Q000494:pharmacology; D009269:Nalorphine / Q000008:administration & dosage / Q000494:pharmacology; D009270:Naloxone / Q000008:administration & dosage / Q000494:pharmacology; D051381:Rats; D011930:Reaction Time / Q000187:drug effects; D011957:Receptors, Opioid / Q000187:drug effects*; D013375:Substance Withdrawal Syndrome / Q000139:chemically induced / Q000503:physiopathology; D019966:Substance-Related Disorders / Q000209:etiology* / Q000503:physiopathology; D013997:Time Factors
chemical_list: D011957:Receptors, Opioid; D009270:Naloxone; D009020:Morphine; D009269:Nalorphine