Fluorometric study of interaction between ACTH fragments and bovine adrenocortical membranes.
Corticotropin 1-24 and [Gly1]corticotropin1-18 amide increased the fluorescence of 1-anilinonaphthalene-8-sulfonate which bound to the bovine adrenocortical membranes. The two ACTH fragments interacted with the protein of the membranes and membranes and increased the net positive charge of the membranes.
D000302:Adrenal Cortex / Q000187:drug effects* / Q000378:metabolism; D000311:Adrenal Glands / Q000187:drug effects*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000817:Anilino Naphthalenesulfonates / Q000378:metabolism*; D000818:Animals; D002417:Cattle; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D003366:Cosyntropin / Q000494:pharmacology; D005453:Fluorescence; D010446:Peptide Fragments / Q000494:pharmacology; D010740:Phospholipases / Q000494:pharmacology; D011402:Pronase / Q000494:pharmacology; D011955:Receptors, Drug
D000817:Anilino Naphthalenesulfonates; D010446:Peptide Fragments; D011955:Receptors, Drug; D003366:Cosyntropin; D000324:Adrenocorticotropic Hormone; D010740:Phospholipases; D011402:Pronase