Effectiveness of theophylline to increase cyclic AMP levels and force of contraction in electrically paced guinea-pig auricles. Comparison with isoprenaline, calcium and ouabain.
D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D002304:Cardiac Pacing, Artificial; D000242:Cyclic AMP / Q000378:metabolism*; D005260:Female; D006168:Guinea Pigs; D066298:In Vitro Techniques; D007545:Isoproterenol / Q000494:pharmacology*; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects*; D009206:Myocardium / Q000378:metabolism*; D010042:Ouabain / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology; D013806:Theophylline / Q000494:pharmacology*; D013997:Time Factors
D010042:Ouabain; D011433:Propranolol; D013806:Theophylline; D000242:Cyclic AMP; D007545:Isoproterenol; D002118:Calcium