Type IIa hyperlipoproteinemia and the HLA system.
The comparative study of a control group made up of 340 healthy subjects, a group of 100 unrelated patients, all showing signs of type II hyperlipoproteinemia and a family of 15 members covering three successive generations, brings to light the highly significant increase of the recurrence of HLA Bw17 antigen and the increase in frequency of HLA Bw35 antigen.
D005787:Gene Frequency; D006680:HLA Antigens; D006650:Histocompatibility Testing; D006801:Humans; D006937:Hypercholesterolemia / Q000276:immunology; D006949:Hyperlipidemias / Q000235:genetics*; D008077:Lipoproteins, LDL / Q000097:blood; D010375:Pedigree
D006680:HLA Antigens; D008077:Lipoproteins, LDL