[Fractional composition of cytoplasmic RNP-particles in the cells of Zajdela ascitic hepatoma and the liver of a tumor-bearing animal].
The relative content of poly(A)-RNA in the cytoplasm was greater in the cells of Zajdela hepatoma and the liver of tumour-bearing rats than in the normal hepatocytes of rats. Besides, the tumour cells (and to a lesser extent the hepatocytes of the tumour-bearing animal) were characterized by the changes in the ratio of the polyribosomes and monoribosomes usual for normal hepatocytes (and correspondingly between the m-RNP-particles and the informosomes) in favour of the latter, this pointing to definite changes in their protein-synthesizing apparatus. As judged by some of the parameters, the cells of the tumour-bearing by some of the parameters, the cells of the tumour-bearing animal occupied an intermediate position between the normal and tumour cells.
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000032:analysis*; D002499:Centrifugation, Density Gradient; D002586:Cesium; D002712:Chlorides; D008099:Liver / Q000032:analysis*; D008113:Liver Neoplasms / Q000032:analysis*; D008297:Male; D009363:Neoplasm Proteins / Q000032:analysis; D009374:Neoplasms, Experimental; D009698:Nucleoproteins / Q000032:analysis*; D051381:Rats; D012261:Ribonucleoproteins / Q000032:analysis*; D013395:Sucrose
D002712:Chlorides; D009363:Neoplasm Proteins; D009698:Nucleoproteins; D012261:Ribonucleoproteins; D002586:Cesium; D013395:Sucrose
Osobennosti fraktsionnogo sostava tsitoplazmaticheskikh RNP-chastits v kletkakh astsitnoĭ gepatomy Zaĭdela i pecheni zhivotnogo s opukhol'iu