Interferon production and activity in mouse neuroblastoma cells.
Mouse neuroblastoma cells are capable of synthesizing interferon after induction with virus or polynucleotides. Differentiation of neuroblastoma cells depresses interferon synthesis without an apparent effect on sensitivity to interferon.
D000818:Animals; D003994:Bucladesine / Q000494:pharmacology; D002454:Cell Differentiation / Q000187:drug effects; D002460:Cell Line; D007372:Interferons / Q000096:biosynthesis* / Q000494:pharmacology; D051379:Mice; D009447:Neuroblastoma; D009522:Newcastle disease virus / Q000254:growth & development; D010222:Parainfluenza Virus 1, Human / Q000254:growth & development; D011070:Poly I-C / Q000494:pharmacology; D013806:Theophylline / Q000494:pharmacology; D014721:Vesicular stomatitis Indiana virus / Q000187:drug effects
D003994:Bucladesine; D007372:Interferons; D013806:Theophylline; D011070:Poly I-C