African green monkey fibroblast actin morphology during SV40 infection.
Monkey skin fibroblasts were infected with simian virus 40. Cells that exhibited the viral tumor antigen were found to retain the normal morphology of actin filaments up to six days after infection. However when cells were transformed in terms of focus formation they had lost the normal actin morphology.
D000199:Actins / Q000378:metabolism*; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D002478:Cells, Cultured; D003599:Cytoskeleton / Q000378:metabolism / Q000648:ultrastructure; D005347:Fibroblasts / Q000648:ultrastructure; D000882:Haplorhini; D066298:In Vitro Techniques; D009858:Oncogenic Viruses / Q000032:analysis; D013539:Simian virus 40 / Q000276:immunology; D012867:Skin / Q000648:ultrastructure
D000199:Actins; D000956:Antigens, Viral