The effect of experimental uremia on potassium-activated phosphatase from erythrocyte and cardiac membranes.
Unilateral nephrectomy and partial resection of the contralateral kidney in rats causes uremia that lasts for several weeks and influenced overall (Na+, K+)-ATPase activity as well as p-nitrophenyl phosphatase (p-NPPase) in the plasma membranes of erythrocytes and heart. Both enzymatic activities are inhibited to a similar extent in the uremic animals, regardless of whether the membranes were investigated one or four weeks after surgical treatment.
D009597:4-Nitrophenylphosphatase / Q000378:metabolism*; D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D004910:Erythrocyte Membrane / Q000201:enzymology*; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D066298:In Vitro Techniques; D009206:Myocardium / Q000201:enzymology* / Q000648:ultrastructure; D009392:Nephrectomy; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism; D051381:Rats; D012508:Sarcolemma / Q000201:enzymology; D012964:Sodium / Q000378:metabolism; D014511:Uremia / Q000201:enzymology*
D012964:Sodium; D010744:Phosphoric Monoester Hydrolases; D009597:4-Nitrophenylphosphatase; D000251:Adenosine Triphosphatases; D011188:Potassium