[Renal production and excretion of AMPc after intravenous infusion of salmon calcitonin in man].
Intravenous infusion of salmon calcitonin in man produced an increase in the plasma levels and urinary excretion of cyclic AMP. This study demonstrates a net extraction of cyclic AMP from plasma by the kidneys but salmon calcitonin does not act only on the kidney and stimulates the production of cyclic AMP in extra renal tissues. The excess of cyclic AMP formed is catabolized by the kidneys.
D000328:Adult; D000618:Aminohippuric Acids / Q000032:analysis; D002116:Calcitonin / Q000097:blood / Q000494:pharmacology*; D002118:Calcium / Q000032:analysis; D000242:Cyclic AMP / Q000096:biosynthesis* / Q000097:blood / Q000652:urine; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007263:Infusions, Parenteral; D007444:Inulin / Q000008:administration & dosage / Q000032:analysis; D007668:Kidney / Q000187:drug effects*; D008297:Male; D012964:Sodium / Q000032:analysis; D013268:Stimulation, Chemical
D000618:Aminohippuric Acids; D007444:Inulin; D002116:Calcitonin; D012964:Sodium; D000242:Cyclic AMP; D002118:Calcium
Etude de la production et de l'excrétion rénale d'AMPc après perfusion intraveineuse de calcitonine de Saumon chez l'Homme?29H