Regional distribution of beta-lipotropin converting enzymes in rat pituitary and brain.
Among the brain areas studied only pars distalis and pars intermedia are found to contain beta-lipotropin activating enzyme indicating the these may be the exclusive organs for a physiologically significant conversion of beta-lipotropin into beta-endorphin. beta-Endorphin inactivating enzyme is found to be rather uniformly distributed in all the pituitary and brain regions. alpha-and gamma-endorphins are presumably formed by the action of the enzyme on beta-endorphin.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D002540:Cerebral Cortex / Q000201:enzymology; D004723:Endorphins / Q000378:metabolism*; D008077:Lipoproteins, LDL / Q000378:metabolism*; D008297:Male; D010447:Peptide Hydrolases / Q000032:analysis*; D010902:Pituitary Gland / Q000201:enzymology*; D051381:Rats
D004723:Endorphins; D008077:Lipoproteins, LDL; D010447:Peptide Hydrolases