title: Alpha-chain disease. A case report with autopsy findings.
abstract: A 19-year-old Coloured man with alpha-chain disease died after perforation of a lymphoma in the duodenojejunal region. At autopsy he was found to have a dense plasma cell infiltration of the lamina propria of the entire small bowel, causing thickening of that organ, and a malignant lymphoma in the duodenojejunal region which had spread to regional mesenteric nodes and to the liver only.
mesh_terms: D000328:Adult; D001344:Autopsy; D003586:Cytomegalovirus Infections / Q000150:complications; D004386:Duodenum / Q000473:pathology; D006362:Heavy Chain Disease / Q000150:complications / Q000473:pathology*; D006801:Humans; D007143:Immunoglobulin Heavy Chains; D007137:Immunoglobulin alpha-Chains; D007414:Intestinal Neoplasms / Q000150:complications; D007583:Jejunum / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008223:Lymphoma / Q000150:complications; D008297:Male; D008643:Mesentery
chemical_list: D007143:Immunoglobulin Heavy Chains; D007137:Immunoglobulin alpha-Chains