title: [Enzymatic mechanisms for antimicrobial protection of the oral cavity].
abstract: Data on the role of oral lysozyme, ribonuclease, deoxyribonuclease and peroxidase in antimicrobial defense of the macroorganism are reviewed. The biochemical and physiological properties of the enzymes secreted by salivary glands and released from emigrating leukocytes are discussed. Spectra of antimicrobial action of the enzymes and participation of these enzymes in maintaining the stability of oral biocenosis are described as well as the regulation of these enzymatic activities and the pathogenetic significance of impairments in their secretion. The most perspective aspects of the problems discussed are outlined for further investigation.
mesh_terms: D000818:Animals; D001409:Bacillus cereus / Q000187:drug effects; D001410:Bacillus megaterium / Q000187:drug effects; D003731:Dental Caries / Q000201:enzymology; D003851:Deoxyribonucleases / Q000502:physiology*; D004926:Escherichia coli / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D005891:Gingivitis / Q000201:enzymology; D006801:Humans; D007778:Lactobacillus / Q000187:drug effects; D007891:Leishmania / Q000187:drug effects; D009055:Mouth / Q000382:microbiology*; D009113:Muramidase / Q000502:physiology*; D009174:Mycoplasma / Q000187:drug effects; D009504:Neutrophils / Q000201:enzymology*; D009195:Peroxidase / Q000502:physiology; D010544:Peroxidases / Q000502:physiology*; D012260:Ribonucleases / Q000502:physiology*; D012463:Saliva / Q000201:enzymology; D012469:Salivary Glands / Q000201:enzymology*; D013210:Staphylococcus / Q000187:drug effects; D013280:Stomatitis / Q000201:enzymology; D013291:Streptococcus / Q000187:drug effects; D014780:Viruses / Q000187:drug effects
chemical_list: D010544:Peroxidases; D009195:Peroxidase; D003851:Deoxyribonucleases; D012260:Ribonucleases; D009113:Muramidase
vernacular_title: Fermentativnye mekhanizmy antimikrobnoĭ zashchity rotovoĭ polosti.