Calcium gradient dependent pyrophosphate formation by sarcoplasmic vesicles.
The vesicles of the sarcoplasmic membranes synthesize pyrophosphate from inorganic phosphate. Pyrophosphate synthesis proceeds as long as a calcium gradient is maintained across the vesicular membranes. Pyrophosphate synthesis is inhibited by low concentrations of nucleoside triphosphates.
D000227:Adenine Nucleotides / Q000378:metabolism; D000818:Animals; D001693:Biological Transport, Active; D002118:Calcium / Q000378:metabolism / Q000494:pharmacology*; D011756:Diphosphates / Q000096:biosynthesis*; D007292:Inosine Nucleotides / Q000378:metabolism; D007700:Kinetics; D008566:Membranes / Q000187:drug effects / Q000378:metabolism; D009132:Muscles; D011817:Rabbits; D012519:Sarcoplasmic Reticulum / Q000187:drug effects / Q000378:metabolism*
D000227:Adenine Nucleotides; D011756:Diphosphates; D007292:Inosine Nucleotides; D002118:Calcium