title: Hepatic amebiasis in spider monkeys.
abstract: In the past, investigators have been able to produce hepatic amebiasis in laboratory animals only by direct introduction of parasites into the liver or its vasculature, or by other artificial manipulations. A natural model of human visceral amebiasis has been lacking. We document an extensive outbreak of amebic dystentery which took place in a colony of spider monkeys; severe hepatic abscesses occurred in many animals. The spider monkey is highly susceptible to infection with Entamoeba histolytica and could provide a valuable model for the study of the pathogenesis of invasive amebiasis.
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D004196:Disease Outbreaks / Q000662:veterinary*; D004748:Entamoeba histolytica / Q000302:isolation & purification; D000882:Haplorhini; D008099:Liver / Q000469:parasitology; D008101:Liver Abscess, Amebic / Q000453:epidemiology* / Q000469:parasitology; D008992:Monkey Diseases / Q000453:epidemiology* / Q000469:parasitology