Blockade of presynaptic alpha-receptors and of amine uptake in the rat brain by the antidepressant mianserine.
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism* / Q000502:physiology; D003984:Dibenzazepines / Q000494:pharmacology*; D004558:Electric Stimulation; D007099:Imipramine / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D008803:Mianserin / Q000494:pharmacology*; D009206:Myocardium / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects*; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects*; D012701:Serotonin / Q000378:metabolism*; D013574:Synaptosomes / Q000378:metabolism
D003984:Dibenzazepines; D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D008803:Mianserin; D012701:Serotonin; D007099:Imipramine; D009638:Norepinephrine