The effect of dibromothymoquinone on respiratory and photosynthetic electron transport in Rhodopseudomonas capsulata chromatophores.
Dibromothymoquinone has been shown to inhibit light-induced cytochrome b reduction, and oxidation of succinate and NADH by chromatophores of Rhodopseudomonas capsulata. The half-inhibitory concentration of light-induced reactions and NADH oxidation is 2.5 muM, but of succinate oxidation is 16 muM. Hexane extraction inhibited oxidation of NADH and succinate equally. The results are interpreted to suggest that ubiquinone is concerned in all three processes described, but that the pools associated with NADH and succinate oxidation are not equally accessible to dibromothymoquinone.
D020130:Bacterial Chromatophores / Q000378:metabolism*; D003580:Cytochromes / Q000378:metabolism; D003991:Dibromothymoquinone / Q000494:pharmacology*; D004579:Electron Transport / Q000187:drug effects; D009243:NAD / Q000378:metabolism; D010788:Photosynthesis / Q000187:drug effects*; D011809:Quinones / Q000494:pharmacology*; D012241:Rhodopseudomonas / Q000378:metabolism*; D013386:Succinates / Q000378:metabolism; D014451:Ubiquinone / Q000378:metabolism
D003580:Cytochromes; D011809:Quinones; D013386:Succinates; D009243:NAD; D014451:Ubiquinone; D003991:Dibromothymoquinone