title: [Postnatal and transplacental carcinogenic effects of methyl methanesulphonate (MMS) and ethyl methanesulphonate (EMS) in hooded rats (author's transl)].
abstract: In the last years numerous investigations of the preferentially neurotropic carcinogenic action of different indirectly alkylating N-nitroso-compounds have been reported. Contrary to these the nuber of experiments, in which the effect of directly alkylating methyl methanesulphonate (MMS) and ethyl methanesulphonate (EMS) was studied is relatively small. Therefore, in own investigations on 4 groups of hooded rats of the inbred strain E the postnatal and prenatal effects of MMS and EMS were studied.
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D005020:Ethyl Methanesulfonate; D005260:Female; D008698:Mesylates; D008741:Methyl Methanesulfonate; D009374:Neoplasms, Experimental / Q000139:chemically induced* / Q000473:pathology; D009463:Neuroma / Q000139:chemically induced; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D051381:Rats
chemical_list: D008698:Mesylates; D005020:Ethyl Methanesulfonate; D008741:Methyl Methanesulfonate
vernacular_title: Zur postnatalen und transplazentaren kanzerogenen Wirkung von Methylmethansulfonat (MMS) und Athylmethansulfonat (AMS) bei der Haubenratte.