[Incidence and specificity of circulating immune complexes in infectious mononucleosis (proceedings)].
Occurrence of immune complexes in infectious mononucleosis has been investigated by the 125I Clq binding assay. Increased serum Clq-binding activity was found in 87% of the 23 patients studied during the acute stage of the disease. The serum Clq-binding material detected has properties identical to those of immune complexes. IgG antibodies dissociated from the complexes at acid pH and F (ab)'2 fragments obtained after treatment by pepsin appeared to be directed against the viral capsid antigen of Epstein-Barr virus.
D000914:Antibodies, Viral; D000918:Antibody Specificity; D000936:Antigen-Antibody Complex; D002213:Capsid; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D007158:Immunologic Techniques; D007244:Infectious Mononucleosis / Q000276:immunology*
D000914:Antibodies, Viral; D000936:Antigen-Antibody Complex
Incidence et spécificité des complexes immuns circulants dans la mononucléose infectieuse.