[A new technic to evaluate the sensitivity of the renal parathyroid hormone receptor in man].
We propose a simplified assessment of response to parathyroid hormone which could replace the traditional Ellsworth Howard test for the differential diagnosis of pseudohypoparathyroidism in man. We have demonstrated that bovine parathyroid hormone in normal and hypoparathyroid subject increases plasma cAMP except in pseudohypoparathyroid subjects. It is an efficient, reliable method without any collection of urine samples.
D002675:Child, Preschool; D000242:Cyclic AMP / Q000097:blood*; D006801:Humans; D007011:Hypoparathyroidism / Q000097:blood; D010281:Parathyroid Hormone / Q000494:pharmacology*; D011547:Pseudohypoparathyroidism / Q000097:blood / Q000175:diagnosis*; D011956:Receptors, Cell Surface / Q000032:analysis*
D010281:Parathyroid Hormone; D011956:Receptors, Cell Surface; D000242:Cyclic AMP
Une nouvelle technique d'appréciation de la sensibilité du récepteur rénal à la parathormone chez l'homme