Transmission of a mucosal disease virus infection between sheep.
The transmission of mucosal disease virus (MDV) from infected ewes and their lambs to susceptible sheep was investigated. MDV was recovered from the amniotic fluid of an infected pregnant ewe and from the blood, nasal swabs and urine of hairy lambs. MDV infection was transmitted either at lambing, from infective foetal fluids or lambs, or later as a result of contact with a surviving with a hairy lamb and either aborted or gave birth to an infected hairy lamb. Adult sheep and 12-months-old sheep were less readily infected than were newborn lambs. Pregnant ewes were infected by contact with a hairy lamb and either aborted or gave birth to an infected hairy lamb. A method to minimise spread of the infection in the field is suggested.
D000818:Animals; D000831:Animals, Newborn / Q000382:microbiology; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000382:microbiology / Q000635:transmission*; D002417:Cattle; D002418:Cattle Diseases / Q000635:transmission*; D001908:Diarrhea Viruses, Bovine Viral / Q000302:isolation & purification; D005260:Female; D005333:Fetus / Q000382:microbiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology / Q000635:transmission*