Protective effect of early serum from mice after cytomegalovirus infection.
Serum obtained from mice 3 to 5 days after cytomegalovirus infection contained complement-requiring neutralizing antibody, which, when passively transferred, protected mice from lethal infection with the homologous virus. The active substance was largely heat-stable 7s immunoglobulin.
D000818:Animals; D000914:Antibodies, Viral / Q000627:therapeutic use; D000937:Antigen-Antibody Reactions; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000276:immunology* / Q000628:therapy; D007109:Immunity; D007167:Immunotherapy; D007372:Interferons / Q000627:therapeutic use; D051379:Mice
D000914:Antibodies, Viral; D007372:Interferons