[Action of a new synthetic ACTH drug in psoriatic arthropathy].
In light of observations in 10 patients the author reports the results of a course of therapy with synthetic depot tetracosactide (SYNACTHEN DEPOT) in psoriatic arthritis. In 2 patients no improvement was evident, while in 3 patients temporary improvement was observed but the effect of the drug was inadequate except in combination. In 5 patients, following intramuscular administration of 1 mg without any other medication, improvement in the symptoms and the objective articular findings, where ankylosis was not present, was observed within a few hours and this improvement lasted for more than one week.
D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage / Q000138:chemical synthesis / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D001168:Arthritis / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy*
D000324:Adrenocorticotropic Hormone
Wirkung eines synthetischen ACTH-Präparates bei psoriatischer Arthropathie