[Hyperlipemia and diabetes].
There are several causes for hyperlipemia in the diabetic: (a) an increase in hepatic synthesis of prebetalipoproteins, and (b) reduced elimination of prebetalipoproteins and chylomicrons from the bloodstream, due to diminished activity of lipoprotein lipase in insulin deficiency. The role of heredity has been put in doubt by the observation that diabetes and hypertriglyceridemia are not transmitted by the same genetic factor. The shortterm and longterm implications of diabetic hyperlipemia are discussed, together with the treatment.
D002914:Chylomicrons / Q000378:metabolism; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000235:genetics; D006801:Humans; D006949:Hyperlipidemias / Q000209:etiology*; D008079:Lipoproteins, VLDL / Q000096:biosynthesis*; D008099:Liver / Q000378:metabolism; D014280:Triglycerides / Q000378:metabolism
D002914:Chylomicrons; D008079:Lipoproteins, VLDL; D014280:Triglycerides
Hyperlipémie et diabète