Infectious mononucleosis and fatal myocarditis.
Mycocarditis is an uncommon manifestation and, very rarely, a lethal complication of infectious mononucleosis. A 14-year-old girl initially had exudative pharyngitis and splenomegaly and developed refractory ventricular fibrillation. The diagnosis of infectious mononucleosis was confirmed by both a strongly positive heterophil antibody test and a high titer of Epstein-Barr virus. Pathologic studies demonstrated extensive histiocytic and lypmhocytic infiltration of the myocardium.
D000293:Adolescent; D000914:Antibodies, Viral / Q000032:analysis; D001344:Autopsy; D005260:Female; D004854:Herpesvirus 4, Human / Q000032:analysis; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications* / Q000175:diagnosis; D009205:Myocarditis / Q000209:etiology*; D009206:Myocardium / Q000473:pathology; D010612:Pharyngitis / Q000209:etiology; D013154:Spleen / Q000473:pathology; D013163:Splenomegaly / Q000209:etiology; D014693:Ventricular Fibrillation / Q000209:etiology
D000914:Antibodies, Viral