An assessment by competition hybridization of the sequence homology between the RNAs of the seven serotypes of FMDV.
A comparison has been made of the RNAs of the seven serotypes of foot-and-mouth disease virus (FMDV) by competition hybridization. Homology among the three European serotypes A, O, C and the Asia I serotype was 60 to 70%. Similar homologies were found among the three Southern African Territories serotypes (SAT I, SAT 2, SAT 3), but homology between the two groups was much lower (25 to 40%). Homology between the RNAs of subtypes within serotypes A and O was greater than 70%. Double competition experiments with the Eropean serotypes indicate sharing of nucleotide sequences.
D005537:Aphthovirus / Q000032:analysis* / Q000145:classification; D001483:Base Sequence; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D012367:RNA, Viral / Q000032:analysis*; D012703:Serotyping
D012367:RNA, Viral