Multiple oncogenesis of neural crest cells by steroids in suckling mice.
In suckling mice injected with steroids, multiple tumors occurred in the sites where neural crest cells normally are present. It is speculated that the phase of the cell cycle of the neural crest cells may have something to do with its cell surface and cellular phenotypic expression in the system mediated by cyclic AMP.
D000818:Animals; D000831:Animals, Newborn; D006854:Hydrocortisone; D051379:Mice; D009378:Neoplasms, Multiple Primary / Q000139:chemically induced* / Q000473:pathology; D009380:Neoplasms, Nerve Tissue / Q000139:chemically induced* / Q000473:pathology; D013739:Testosterone / Q000031:analogs & derivatives*
D013739:Testosterone; D006854:Hydrocortisone