title: Changes in trout testis cyclic GMP concentration during hormonally induced spermatogenesis.
abstract: The concentration of cyclic GMP was determined in trout testes (Salmo gairdnerii) during hormonally-induced sermatogenesis. Early in spermatogenesis, a relatively high concentration (1 mumole/kg wet weight testis) of cyclic GMP was present. A sharp, ten-fold, decrease in testis cyclic GMP concentration occurred during the early stages of rapid mitotic activity and testis growth. A further gradual five-fold decrease in cyclic GMP concentration occurred during meiosis and the following transformation of spermatocytes into spermatids and then to mature spermatozoa.
mesh_terms: D000818:Animals; D002455:Cell Division; D006152:Cyclic GMP / Q000378:metabolism*; D008297:Male; D009929:Organ Size; D010907:Pituitary Hormones / Q000494:pharmacology; D013091:Spermatogenesis / Q000187:drug effects; D013737:Testis / Q000033:anatomy & histology / Q000166:cytology / Q000378:metabolism*; D014337:Trout
chemical_list: D010907:Pituitary Hormones; D006152:Cyclic GMP