title: [Effect of the site of microbial aerosol application on the pathogenesis and clinical picture of aerosol infection].
abstract: On the basis of experimental and clinical study of infections with the aerosol mechanism of infection there was revealed a relationship between the fractional-dispersive composition of the microbial aerosol, the porta of infection and the clinico-pathogenetic peculiarities of the course of the disease. On the example of tularemia, plague and other nosological forms it was demonstrated that coarse-dispersive aerosol caused development of oculo-bubonic and anginous-bubonic form of the disease, whereas the high-dispersive aerosol led to the appearance of primary pneumonia. In experimental aerosol infection with the causative agents in which the infection under natural conditions is not air-borne (botulism, American horse encephalo-myelitis, etc.) specific disease as a rule develops without any primary affection of the respiratory organs.
mesh_terms: D000257:Adenoviridae Infections / Q000635:transmission; D000336:Aerosols; D000818:Animals; D000881:Anthrax / Q000635:transmission; D004165:Diphtheria / Q000635:transmission; D000882:Haplorhini; D006801:Humans; D007239:Infections / Q000635:transmission*; D007251:Influenza, Human / Q000635:transmission; D008253:Macaca mulatta; D002679:Pan troglodytes; D010930:Plague / Q000635:transmission; D009956:Psittacosis / Q000635:transmission; D012541:Scarlet Fever / Q000635:transmission; D014406:Tularemia / Q000635:transmission
chemical_list: D000336:Aerosols
vernacular_title: Vliianie mesta applikatsii mikrobnogo aérozolia na patogenez i kliniku aerozol'noi infektsii