[Anti hepatitis A antibodies in the French population and in polyvalent plasma immunoglobulins at a transfusion center (Gamma TS)].
A search for antibodies directed specifically against hepatitis virus A was carried out in 600 blood donors in the Paris region (354 men and 246 women) by a radio-immunological technic in solid phase. 75.3% had a positive test, no difference was found as regards sex on country of origin (57 were not French). An increase in the frequency of carriers of anti-HAV carriers was observed in relation to age, for 48.4% were aged between 18 and 24 years and 85.9% had antibodies after age 40 years. An estimation of anti-HAV antibodies was made on 19 lots of immunoglobulins from French transfusion centers by the same technic. High and homogenous levels were observed (average 1/4 270). These data were discussed and compared with those in the literature. A better prophylaxis of hepatitis A and the determination of specific activity of polyvalent immunoglobulins with regard to this virus is then considered.
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral; D001782:Blood Donors; D001803:Blood Transfusion; D005260:Female; D005602:France; D006507:Hepatovirus / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G; D008297:Male; D008875:Middle Aged
D000914:Antibodies, Viral; D007074:Immunoglobulin G
Anticorps anti-hépatite A dans la population française et dans les immunoglobulines plasmatiques polyvalentes des centres de transfusion (Gamma TS).