title: Inhibition of phosphodiesterase activity of human spermatozoa by spermine.
abstract: Sperm motility and metabolism are dependent upon the levels of cyclic AMP. Our studies have demonstrated that spermine by inhibiting sperm phosphodiesterase activity could regulate sperm physiology.
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D008297:Male; D013094:Spermatozoa / Q000201:enzymology*; D013096:Spermine / Q000494:pharmacology*
chemical_list: D013096:Spermine; D015105:3',5'-Cyclic-AMP Phosphodiesterases