Recurrent genital Herpes simplex virus (HSV) infection of guinea pigs.
Intravaginal infection of guinea pigs with HSV type 2 induced lesions resembling genital herpes in humans. Chronic latent infection with spontaneously recurring genital lesions developed in animals surviving the primary disease. Clinical observations and virological studies during the acute and chronic infection are reported.
D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D005727:Ganglia, Spinal / Q000382:microbiology; D005831:Genital Diseases, Female / Q000382:microbiology; D006168:Guinea Pigs; D006561:Herpes Simplex / Q000382:microbiology; D012008:Recurrence; D012584:Sciatic Nerve / Q000382:microbiology; D018139:Simplexvirus / Q000302:isolation & purification; D012867:Skin / Q000382:microbiology; D013116:Spinal Cord / Q000382:microbiology; D014599:Uterus / Q000382:microbiology; D014621:Vagina / Q000382:microbiology