title: Computed tomographic evaluation of therapeutically induced changes in primary and secondary brain tumors.
abstract: A prospective study was initiated to evaluate computed tomography as a method for monitoring therapeutically induced changes in brain tumors. Early postoperative scans may be misleading in the evaluation of residual tumor because of trauma to the blood-brain barrier during operation. The size of the dominant mass (17/25), enhancement (11/25), edema (11/25), and ventricular distortion (14/25) were decreased in many patients after radiation therapy. Occasional tumors increased in size during radiation therapy (3/25). Enlargement of the lateral ventricles developed in 9 of 25 patients. Computed tomography offers definite advantages over nuclide brain scans, angiography and other diagnostic studies for evaluating therapeutically induced changes in brain tumors.
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000628:therapy*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy; D005260:Female; D005909:Glioblastoma / Q000000981:diagnostic imaging / Q000628:therapy; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy; D008297:Male; D008527:Medulloblastoma / Q000000981:diagnostic imaging / Q000628:therapy; D008545:Melanoma / Q000000981:diagnostic imaging / Q000628:therapy; D009362:Neoplasm Metastasis; D010871:Pinealoma / Q000000981:diagnostic imaging / Q000628:therapy; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed