[Effects of zinc-aerosols on the inhalation toxicity of cadmium (author's transl)].
Female rats were continuously exposed for 3 months to an aerosol containing 50 micrograms/m3 Cadmium-Oxyd and 1.25 mg/m3 Zinc-Oxyd. Our results were compared with those of Prigge (1977), who studied the CdO-toxicity under equal conditions. Inour investigations we studied with clinical and clinico-chemical methods a possible protective effect of ZnO on the Cd-toxicity, given simultanously. A protective effect of ZnO on the Cd-toxicity was evident in out investigations in form of a reduced deposition of Cd in lungs, in livers and kidneys. A reduction of the cadmium-induced hyperplasia of lungs was a remarkable sign for a protective action of Zn. There are some criterions, that Zn, given simultaneously in the studied concentrations, can inhibit the Cd-induced disorder of function in kidneys.
D000336:Aerosols; D000818:Animals; D002104:Cadmium / Q000097:blood / Q000378:metabolism; D002105:Cadmium Poisoning / Q000378:metabolism / Q000517:prevention & control*; D005260:Female; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D051381:Rats; D015032:Zinc / Q000627:therapeutic use*; D015034:Zinc Oxide / Q000008:administration & dosage / Q000627:therapeutic use*
D000336:Aerosols; D002104:Cadmium; D015032:Zinc; D015034:Zinc Oxide
Der Einfluss von Zink-Aerosolen auf die Inhalationstoxizität von Cadmium.