title: Evaluation of otic drops on infection and healing of traumatic tympanic membrane perforations.
abstract: Guinea pigs were used to compare the efficacy of three commercially available otic preparations in treating traumatic tympanic membrane perforations. The results suggest that a clear, viscous solution of low pH will significantly reduce the incidence of infection and will not retard subsequent membrane healing.
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D003091:Colistin / Q000627:therapeutic use; D006168:Guinea Pigs; D006854:Hydrocortisone / Q000627:therapeutic use; D009355:Neomycin / Q000627:therapeutic use; D011113:Polymyxins / Q000627:therapeutic use; D012421:Rupture / Q000188:drug therapy*; D012996:Solutions; D014432:Tympanic Membrane; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D011113:Polymyxins; D012996:Solutions; D009355:Neomycin; D006854:Hydrocortisone; D003091:Colistin