title: Serum phosphodiesterase I activity in breast cancer patients.
abstract: Serum phosphodiesterase I (PDE I) activity was determined in 13 control and 51 breast-cancer patients with various stages of disease. Patients with both localized and metastatic breast cancer had significantly elevated serum PDE I activity. The highest activity was seen in patients with liver metastases. A decline in serum PDE I activity was seen after surgical resection of all known disease.
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood; D001943:Breast Neoplasms / Q000201:enzymology* / Q000601:surgery; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000201:enzymology / Q000556:secondary; D010727:Phosphoric Diester Hydrolases / Q000097:blood*
chemical_list: D000469:Alkaline Phosphatase; D010727:Phosphoric Diester Hydrolases