[The treatment of Cushing's syndrome by selective excision of pituitary adenoma. 3 cases (author's transl)].
In three patients suffering from Cushing's disease, exploration revealed an enclosed pituitary adenoma in one case and a microadenoma in two cases. Selective excision via a transphenoidal approach resulted in cure of Cushing's disease as reflected by complete regression of clinical signs and the restoration of circadian rythm of cortisol. Regular follow-up over a period of more than two years showed the persistence of normal regulation of the corticotrophic sector of the pituitary.
D000236:Adenoma / Q000150:complications / Q000601:surgery*; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D002940:Circadian Rhythm; D003480:Cushing Syndrome / Q000209:etiology / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications / Q000601:surgery*
D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
Maladie de Cushing: traitement par exérèse sélective de l'adénome hypophysaire. 3 observations.