Cell DNA induction by human cytomegalovirus.
The studies presented indicate that in cells pretreated with IUDR: (1) a temporal relationship exists between CMV and cell DNA synthesis; (2) in cells pretreated with IUDR only a fraction of the cell genome is induced by the virus to replicate; and (3) cell DNA induced by the virus to replicate represents unique rather than repetitive DNA sequences.
D001483:Base Sequence; D002472:Cell Transformation, Viral; D002478:Cells, Cultured; D003587:Cytomegalovirus / Q000378:metabolism*; D004247:DNA / Q000096:biosynthesis*; D004261:DNA Replication / Q000187:drug effects; D004279:DNA, Viral / Q000096:biosynthesis; D006801:Humans; D007065:Idoxuridine / Q000494:pharmacology; D008168:Lung; D009693:Nucleic Acid Hybridization; D013997:Time Factors
D004279:DNA, Viral; D004247:DNA; D007065:Idoxuridine