Thorotrast induced hepatic cholangiocarcinoma and angiosarcoma.
A 49 year old woman developed hepatic cholangiocarcinoma and angiosarcoma 22 years after the administration of Thorotrast. The etiologic association between Thorotrast and a variety of malignant hepatic neoplasms is well known, but the simultaneous occurrence of two different hepatic neoplasms has not been previously reported.
D002759:Adenoma, Bile Duct / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006394:Hemangiosarcoma / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000473:pathology; D008875:Middle Aged; D009362:Neoplasm Metastasis; D013154:Spleen / Q000473:pathology; D013911:Thorium Dioxide / Q000009:adverse effects*
D013911:Thorium Dioxide