Immunoreactivity for beta-endorphin in LH-RH neurons of the fetal human hypothalamus.
A peptide immunochemically related to beta-endorphin was detected in some LH-RH neurons of the fetal human hypothalamus by comparison of adjacent sections stained for beta-endorphin and for LH-RH. In the same section, by successive staining and after antibody elution, both peptides were again revealed in the same neuron. The significance of the presence of the beta-endorphin-like material in LH-RH neurons is discussed.
D000324:Adrenocorticotropic Hormone / Q000032:analysis; D001923:Brain Chemistry; D004723:Endorphins / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D007987:Gonadotropin-Releasing Hormone / Q000032:analysis*; D006801:Humans; D007031:Hypothalamus / Q000032:analysis* / Q000166:cytology / Q000196:embryology; D007124:Immunoenzyme Techniques; D009474:Neurons / Q000032:analysis
D004723:Endorphins; D007987:Gonadotropin-Releasing Hormone; D000324:Adrenocorticotropic Hormone