title: Kinetic studies of the interaction of uranyl ions with inorganic pyrophosphatase from baker's yeast.
abstract: Kinetic measurements were performed to test the effect of uranyl ions on the enzymatic hydrolysis of pyrophosphate. A strong inhibition of the enzyme was found. From a Dixon-plot an inhibition competitive to the substrate magnesium pyrophosphate and an inhibitory constant of Ki = 3 . 10(-7) M was deduced.
mesh_terms: D011756:Diphosphates; D007700:Kinetics; D011755:Pyrophosphatases / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000201:enzymology*; D014501:Uranium / Q000494:pharmacology*
chemical_list: D011756:Diphosphates; D014501:Uranium; D011755:Pyrophosphatases