[Effect of metoclopramide on growth hormone (GH) release induced with ACTH].
We examined 10 volunteers subjects, sound and exempt from endocrine disease. The rapid injection of 0,25 mg of ACTH (Synacten) was followed by a distinct increase of plasma Growth Hormone (GH) within 30 or 60 min in 9 of 10 normal volunteers. The test were then repeated in the 12 "responders" after previous subministration of Metoclopramide and the GH response was totally abolished.
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000328:Adult; D000818:Animals; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008787:Metoclopramide / Q000494:pharmacology*; D013268:Stimulation, Chemical
D000324:Adrenocorticotropic Hormone; D013006:Growth Hormone; D008787:Metoclopramide
Effetto della metoclopramide sulla liberazione di GH indotta dall'ACTH.