title: [Ultrastructural study in four cases of cutaneous xanthomas in children (author's transl)].
abstract: Three cases are associated with a Reclinghausen disease. Histological findings show typical xanthoma. Electron microscopical study indicates: --numerous intracytoplasmic lipid inclusions of various type (droplets, crystals, concentric lamellar bodies, ceroid granules) in dermal cells (histiocytic foam cells, endothelial cells, Schwann cells, fibroblasts and most cells); --large intranuclear inclusions in some histiocytes containing few lipids droplets; these figures could be compared to a slice of "petrified wood"; their significance is as yet unknown (Liesegang rings?).
mesh_terms: D002467:Cell Nucleus / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003593:Cytoplasm / Q000032:analysis; D005260:Female; D006644:Histiocytes / Q000648:ultrastructure; D006801:Humans; D002479:Inclusion Bodies / Q000473:pathology; D008055:Lipids / Q000032:analysis; D008297:Male; D009456:Neurofibromatosis 1 / Q000150:complications; D012867:Skin / Q000648:ultrastructure; D012871:Skin Diseases / Q000150:complications / Q000473:pathology*; D014973:Xanthomatosis / Q000150:complications / Q000473:pathology*
chemical_list: D008055:Lipids
vernacular_title: Etude ultrastructurale de 4 cas de xanthomes cutanés chez l'enfant.