[Sulindac suppositories: treatment of pain in osteoarthritis (author's transl)].
Thirty one patients with osteoarthritis (29 hips, 16 knees) were submitted to a treatment with sulindac at a daily dose of 200 mg bid suppositories during four weeks. This trial showed that the treatment brought relief of pain in the majority of patients. Compared with others previously prescribed drugs, sulindac was more effective (72%). Sulindac suppositories were well tolerated; only three drop-out because side-effects (gastro intestinal tract: 2, skin 1) have been reported. Sulindac suppositories tolerance was reported as good.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007192:Indenes / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D013467:Sulindac / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D013488:Suppositories
D007192:Indenes; D013488:Suppositories; D013467:Sulindac
Etude du suppositoire de sulindac dans le traitement de la douleur arthrosique.