title: ACTH-adrenal system and exogenous steroids.
abstract: The results obtained from a research on 100 patients of both sexes affected with bronchial asthma, chronic obstructive bronchopathy, rheumatoid arthritis, haematological disorders and some other pathological forms, all depending on steroid therapy, are reported in this paper. The treatment was carried out using a new chronopluricorticoid (Dutimelan 8 15). The clinical efficiency is comparable to that obtained by the traditional steroid treatment with the advantage that symptoms of hypercorticism were absent or insignificant. The authors believe that such excellent results are to be attributed to the particular chronopharmacological characteristics of this preparation.
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000494:pharmacology / Q000627:therapeutic use*; D000324:Adrenocorticotropic Hormone / Q000378:metabolism / Q000502:physiology*; D000328:Adult; D000368:Aged; D002940:Circadian Rhythm; D003095:Collagen Diseases / Q000188:drug therapy; D003348:Cortisone / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D006505:Hepatitis / Q000188:drug therapy; D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000188:drug therapy; D010913:Pituitary-Adrenal System / Q000187:drug effects / Q000502:physiology*; D011239:Prednisolone / Q000627:therapeutic use; D011693:Purpura / Q000188:drug therapy; D012130:Respiratory Hypersensitivity / Q000188:drug therapy
chemical_list: D000305:Adrenal Cortex Hormones; D004338:Drug Combinations; D000324:Adrenocorticotropic Hormone; D011239:Prednisolone; D003348:Cortisone