Adaptation to hypertonicity and selection of cell hybrids.
The ability to survive in hypertonic media varies markedly among different cell strains. This property was exploited to set up a selection procedure to isolate cell hybrids, in cell fusion experiments. The results of a cross between two EUE sublines, with a differential sensitivity to hypertonicity, are discussed.
D000222:Adaptation, Physiological; D002460:Cell Line; D002462:Cell Membrane / Q000502:physiology; D006801:Humans; D006822:Hybrid Cells / Q000502:physiology*; D009994:Osmolar Concentration; D010222:Parainfluenza Virus 1, Human; D012641:Selection, Genetic