Comparative investigations of some enzymatic parameters and liver scanning in the early detection of the malignant liver process.
In 30 patients with histologically verified malignant liver processes, the authors have examined the value of the serum activity of liver lactate dehydrogenase (LDH), alkaline phosphatase and gamma-glutamyltranspeptidase and in a number of patients, 5'-nucleotidase. These values were compared with the findings received from scintigraphy of the liver. Based on the results obtained, the authors have concluded that the activities of the gamma-glutamyltranspeptidase (gammaGT), 5'-nucleotidase and liver lactate dehydrogenase are more significantly increased in malignant processes of the liver than scintigraphy of the liver could register.
D000410:Alanine Transaminase / Q000032:analysis; D000469:Alkaline Phosphatase / Q000097:blood / Q000378:metabolism*; D001219:Aspartate Aminotransferases / Q000032:analysis; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000201:enzymology / Q000473:pathology; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000201:enzymology* / Q000473:pathology; D008113:Liver Neoplasms; D009708:Nucleotidases / Q000097:blood / Q000378:metabolism*; D005723:gamma-Glutamyltransferase / Q000097:blood / Q000378:metabolism*
D007770:L-Lactate Dehydrogenase; D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D009708:Nucleotidases; D000469:Alkaline Phosphatase