Catecholamine secreting tumor of the glomus jugulare.
A case of endocrinologically active glomus jugulare is presented. The localization within the tumor of the catecholamine hyperproduction was demonstrated by selective venous sampling from the vena jugularis externa draining the tumor. The norepinephrine/epinephrine ratio was high and of the same order in blood, urine and cerebrospinal fluid. Bioassay showed high levels of intratumoral norepinephrine and epinephrine. The ways of treatment and their influence on the catecholamines are briefly discussed. In every phaeochromocytoma-like syndrome both the existence of catecholamine hyperproduction and the anatomical site of this hypersecretion have to be precisely documented in order to define the correct treatment to be applied.
D002395:Catecholamines / Q000378:metabolism*; D002533:Cerebral Angiography; D005925:Glomus Jugulare Tumor / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010236:Paraganglioma, Extra-Adrenal / Q000378:metabolism*
D002395:Catecholamines