Electron microscopic demonstration of Crimean hemorrhagic fever virus in CV-1 cells.
Crimean hemorrhagic fever (CHF) virus was detected by electron microscopy in ultrathin sections of CV-1 cells. The virus particles appeared spherical or oval and occurred both intra- and extracellularly. Based on their size and density of their contents, two types of virions, probably representing different phases of the reproduction cycle of CHF virus, could be distinguished.
D000818:Animals; D001103:Arboviruses / Q000302:isolation & purification*; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D003593:Cytoplasm / Q000382:microbiology; D000882:Haplorhini; D003225:Hemorrhagic Fever Virus, Crimean-Congo / Q000254:growth & development / Q000302:isolation & purification* / Q000648:ultrastructure; D007668:Kidney; D014779:Virus Replication