Gibbon ape leukemia virus-Hall's Island: new strain of gibbon ape leukemia virus.
Gibbon ape leukemia virus-Hall's Island (GaLV-H), a type C virus related to previous isolates of GaLV and simian sarcoma virus, was isolated from a gibbon ape with lymphocytic leukemia from a small colony of free-ranging gibbon apes on Hall's Island near Bermuda. We show here by molecular hybridization experiments that GaLV-H is approximately 60% related to three previous isolates of GaLV (GaLV-SF, GaLV-SEATO, and GaLV-Br) and is less closely related to simian sarcoma virus. The oligopyrimidine pattern of a transcript of the terminal 135 +/- 5 nucleotides of the viral RNA of GaLV-H is similar to that of GALV-Br but distinct from that of GaLV-SF and simian sarcoma virus. GaLV-H thus represents a fifth distinct strain of the infectious primate type C viruses, which among the previously described isolates of GaLV is most closely related to GaLV-Br.
D000818:Animals; D001483:Base Sequence; D006922:Hylobates; D009693:Nucleic Acid Hybridization; D012367:RNA, Viral / Q000032:analysis; D012190:Retroviridae / Q000032:analysis / Q000145:classification*; D012842:Sarcoma Virus, Woolly Monkey / Q000032:analysis
D012367:RNA, Viral