The neuromuscular blocking properties of AH 8165 during halothane anaesthesia.
The time to onset, duration, time for reversal, and dose required to abolish twitch response for AH 8165 have been investigated. The drug is shown to be a rapidly acting agent, with a duration of action similar to pancuronium.
D000768:Anesthesia, General; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D006221:Halothane; D006225:Hand / Q000294:innervation; D006801:Humans; D007275:Injections, Intravenous; D009388:Neostigmine / Q000494:pharmacology; D011726:Pyridinium Compounds / Q000008:administration & dosage / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D013997:Time Factors; D014459:Ulnar Nerve / Q000502:physiology
D011726:Pyridinium Compounds; D009388:Neostigmine; D006221:Halothane