[Distribution, absorption and excretion of 198Au-colloid and Na251CrO4 in the chicken (author's transl)].
In order to clarify the suitability of 198Au-colloid and Na251CrO4 as a marker of transit of the gastrointestinal content of the chicken, the distribution, absorption and excretion of 198Au-colloid and Na251CrO4 in the chicken were examined. Orally administered 198Au-colloid was not absorbed by the gastrointestinal tract and excreted into feces. Intravenously injected 198Au-colloid was not excreted into the gastrointestinal tract through the gastrointestinal wall. On the other hand, orally administered Na251CrO4 was relatively well absorbed by the gastrointestinal tract and distributed over a whole body. Intravenously injected Na251CrO4 was excreted into the gastrointestinal tract through the gastrointestinal wall and bile ducts. It seemed that 198Au-colloid was not adhered to the gastrointestinal mucosa and consequently, the transport of 198Au-colloid in the gastrointestinal tract was not delayed. It is concluded that 198Au-colloid is highly suitable as a marker of gastrointestinal transit of the chicken but Na251CrO4 is unsuitable.
D000284:Administration, Oral; D000818:Animals; D002645:Chickens; D002860:Chromium Radioisotopes / Q000008:administration & dosage / Q000378:metabolism*; D005243:Feces / Q000032:analysis; D006048:Gold Colloid, Radioactive / Q000008:administration & dosage / Q000378:metabolism*; D007275:Injections, Intravenous; D007408:Intestinal Absorption; D008297:Male; D014018:Tissue Distribution
D002860:Chromium Radioisotopes; D006048:Gold Colloid, Radioactive