title: The amino acid sequence of fragment A, an enzymically active fragment of diphtheria toxin. I. The tryptic peptides from the maleylated protein.
abstract: Six tryptic peptides ranging in size from 3 to 126 residues were isolated from maleylated Fragment A of diphtheria toxin after tryptic hydrolysis. These peptides accounted for all 193 residues found by amino acid analysis. After demaleylation, the six peptides were purified by chromatography on Sephadex G-50, coupled with paper chromatography and electrophoresis, and were analyzed by various methods. The compositions and properties of the peptides are reported. Almost 70% of the residues were positioned within these peptides.
mesh_terms: D000247:Adenosine Diphosphate Sugars; D000595:Amino Acid Sequence; D004167:Diphtheria Toxin; D008299:Maleic Anhydrides; D009243:NAD; D009713:Nucleotidyltransferases; D010445:Peptide Elongation Factors; D010446:Peptide Fragments / Q000032:analysis; D012266:Ribose / Q000031:analogs & derivatives; D014357:Trypsin
chemical_list: D000247:Adenosine Diphosphate Sugars; D004167:Diphtheria Toxin; D008299:Maleic Anhydrides; D010445:Peptide Elongation Factors; D010446:Peptide Fragments; D009243:NAD; D012266:Ribose; D009713:Nucleotidyltransferases; D014357:Trypsin