A comparison of the inhibitory effects of disodium pyrophosphate and disodium ethane-hydroxy-1, 1-diphosphonate on simple calcergy.
Both disodium pyrophosphate and disodium ethane-hydroxy-1, 1-diphosphate inhibit the reaction of simple calcergy induced in the mouse by lead acetate. The pyrophosphate is effective only by a direct interaction with the lead salt and the disphosphonate is effective only before the occurrence of histochemically demonstrable calcification.
D000818:Animals; D002114:Calcinosis / Q000139:chemically induced / Q000473:pathology / Q000517:prevention & control*; D011756:Diphosphates / Q000627:therapeutic use*; D012968:Etidronic Acid / Q000627:therapeutic use*; D007854:Lead; D008297:Male; D051379:Mice; D012867:Skin / Q000473:pathology; D013997:Time Factors
D011756:Diphosphates; D007854:Lead; D012968:Etidronic Acid