[Vasoactive intestinal peptide (VIP) in the Verner-Morrison syndrome (author's transl)].
An early diagnosis of the Verner-Morrison syndrome will greatly enhance the chances of curative resection. There is a striking need for a simple diagnostic test. A number of suggestions have been made for the presumed hormone mediator of this syndrome. Numerous reports have led to a wide acceptance that vasoactive intestinal peptide (VIP) is the responsible mediator for the pharmacologic actions of this peptide are similar to the physiological characteristics noted in the watery diarrhea syndrome. A raised plasma VIP concentration, on the other hand, would suggest the presence of a tumour. These observations argue for the radioimmunoassay measurement of plasma VIP in a patient with the watery diarrhea syndrome.
D007516:Adenoma, Islet Cell / Q000097:blood / Q000175:diagnosis; D003967:Diarrhea / Q000097:blood / Q000175:diagnosis*; D005768:Gastrointestinal Hormones / Q000097:blood*; D006801:Humans; D007008:Hypokalemia / Q000175:diagnosis*; D010190:Pancreatic Neoplasms / Q000097:blood / Q000175:diagnosis; D011863:Radioimmunoassay; D013577:Syndrome; D014660:Vasoactive Intestinal Peptide / Q000097:blood*
D005768:Gastrointestinal Hormones; D014660:Vasoactive Intestinal Peptide
Le peptide intestinal vasoactif (VIP) au cours du syndrome de Verner-Morrison.