title: 9-(2-hydroxyethoxymethyl)guanine as an inhibitor of herpes simplex virus replication.
abstract: The drug 9-(2-hydroxyethoxymethyl)guanine effectively inhibits herpes simplex virus replication. It is selectively phosphorylated by the virus-induced thymidine kinase but not by normal cellular thymidine kinase.
mesh_terms: D000998:Antiviral Agents; D006147:Guanine / Q000031:analogs & derivatives* / Q000494:pharmacology; D018139:Simplexvirus / Q000187:drug effects*; D014779:Virus Replication / Q000187:drug effects*
chemical_list: D000998:Antiviral Agents; D006147:Guanine