Histochemistry of the post-resuscitation changes in the brain.
In 20 dogs, acid mucopolysaccharides, gangliosides, lysosomal enzymes and iontransport enzymes were investigated. Material was taken 2, 24 and 72 h after 15 min of clinical death due to electrotrauma. Changes in the post-resuscitation period indicated deterioration of transmembrane ion--metabolite transport in the brain. These changes had phasic variations that reflect the complexity of post-resuscitation processes.
D000110:Acetylcholinesterase / Q000378:metabolism; D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism*; D004285:Dogs; D005260:Female; D005732:Gangliosides / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism; D006651:Histocytochemistry; D008247:Lysosomes / Q000378:metabolism; D008297:Male; D009474:Neurons / Q000378:metabolism; D012151:Resuscitation; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism
D005732:Gangliosides; D006025:Glycosaminoglycans; D000110:Acetylcholinesterase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D000254:Sodium-Potassium-Exchanging ATPase