title: [Use of neuroleptic agents in modern pig-farming (author's transl)].
abstract: in pig-farming, the use of neuroleptic agents in conditions causing stress has increased. In the meaty type pig, this stress gives rise to specific symptoms such as acidosis, hyperthermia and muscle rigidity. This will result in death before or an abnormal meat quality (PSE-meat) after slaughter. The symptoms may also be produced in these pigs by having them inhale halothane (Fluothane), the symptoms being rapidly reversible. The inhibitory effect of various neuroleptic agents of the group of butyrophenone and phenothiazine derivatives on the appearance and course of the above symptoms is discussed. The extent to which the quality of the meat and mortality during transport is affected following administration of these agents to slaughter pigs as well as the degree to which hypersensitivity reactions to halothane are reduced in young pigs serve as models. Finally, public health and ethical aspects relating to the use of neuroleptic agents in farm animals are examined more closely.
mesh_terms: D000003:Abattoirs; D000138:Acidosis / Q000209:etiology / Q000662:veterinary; D000818:Animals; D014150:Antipsychotic Agents / Q000627:therapeutic use; D002090:Butyrophenones / Q000627:therapeutic use; D004342:Drug Hypersensitivity / Q000517:prevention & control; D004995:Ethics, Professional; D005334:Fever / Q000209:etiology / Q000662:veterinary; D006221:Halothane / Q000494:pharmacology; D009127:Muscle Rigidity / Q000209:etiology / Q000662:veterinary; D010640:Phenothiazines; D013312:Stress, Physiological / Q000150:complications / Q000517:prevention & control / Q000662:veterinary*; D013552:Swine; D014149:Tranquilizing Agents / Q000627:therapeutic use*; D014730:Veterinary Medicine
chemical_list: D014150:Antipsychotic Agents; D002090:Butyrophenones; D010640:Phenothiazines; D014149:Tranquilizing Agents; D006221:Halothane
vernacular_title: Toepassing van neuroleptica in de moderne varkenshouderij