title: [Amyloid neuropathy associated with a benign monoclonal gammopathy (lambda light chains)].
abstract: The authors report a case of non-familial amyloid neuropathy in which there was sensory-motor neuropathy of the 4 limbs, multiple lesions in the cranial nerves, and large subcutaneous amyloid deposits. Biopsy samples showed the presence of amyloid deposits in the interstitial tissues, the vessel walls in the muscle hypodermis, and in the bone marrow. A light monoclonal lambda chain was present in the serum. Immunofluorescent studies of the biopsy specimens showed the presence of elective fluorescence with an anti-lambda immunoserum in the amyloid substance.
mesh_terms: D000686:Amyloidosis / Q000150:complications* / Q000276:immunology; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007147:Immunoglobulin Light Chains; D007146:Immunoglobulin lambda-Chains; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000150:complications* / Q000276:immunology
chemical_list: D007147:Immunoglobulin Light Chains; D007146:Immunoglobulin lambda-Chains
vernacular_title: Neuropathie amyloide associée à une gammapathie monoclonale bénigne (chaines légeres lambda).