Inhibition of synthesis of pyrimidine nucleotides by 2-hydroxy-3-(3,3-dichloroallyl)-1,4-naphthoquinone.
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000378:metabolism; D002478:Cells, Cultured; D004081:Dihydroorotate Oxidase / Q000037:antagonists & inhibitors; D006801:Humans; D066298:In Vitro Techniques; D007939:Leukemia L1210 / Q000188:drug therapy* / Q000378:metabolism; D051379:Mice; D008815:Mice, Inbred Strains; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism; D009285:Naphthoquinones / Q000494:pharmacology*; D011742:Pyrimidine Nucleotides / Q000096:biosynthesis*
D009285:Naphthoquinones; D011742:Pyrimidine Nucleotides; D004081:Dihydroorotate Oxidase