[Kinetics of bone uptake of 99m Tc-labeled diphosphonates. Preliminary results].
The bone fixation of diphosphonates depends on the degree of osteogenesis, the blood bone flow and the capillary permeability. The precise characteristics of the fixation kinetic are not very well known. The authors propose a new method which makes possible to study them and expose their results. For average persons the fixation curves present an ascending line, an apex, reach within 40 mn and a descending line. Any affection don't seem to have characteristic curves; on the contrary it is possible to have different curves for a same affection which implies doubtless various anatomic and metabolic data.
D001847:Bone Diseases / Q000378:metabolism*; D001859:Bone Neoplasms / Q000378:metabolism*; D001842:Bone and Bones / Q000378:metabolism*; D004164:Diphosphonates / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D012588:Scintillation Counting; D013667:Technetium
D004164:Diphosphonates; D013667:Technetium
Etude de la cinétique de fixation osseuse des diphosphonates marqués au 99m tc. Résultats préliminaires.