Prostaglandin F2 alfa infusion and halothane anaesthesia.
The cardiovascular reaction to infusion of prostaglandin F2 alfa was examined in seven patients during N2O-jalothane anaesthesia. As in the non-anaesthetized individual, no changes in blood pressure, pulse rate, CVP or ECG occurred during anaesthesia, but a great reflux of enteric juice to the ventricle was noticed only 2-3 min after the beginning of the hormone infusion. It is concluded that prostaglandin F2 alfa may be safely given to patients who are going to be anaesthetized, but the patients must be considered as having a full stomach and therefore treated as such.
D000328:Adult; D000758:Anesthesia; D001646:Bile; D001794:Blood Pressure / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects*; D002496:Central Venous Pressure / Q000187:drug effects; D004347:Drug Interactions; D005260:Female; D005750:Gastric Juice; D006221:Halothane / Q000494:pharmacology*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008875:Middle Aged; D011453:Prostaglandins / Q000494:pharmacology*; D012881:Skin Temperature / Q000187:drug effects
D011453:Prostaglandins; D006221:Halothane