The effect of sympathicomimetic agents on carbohydrate metabolism of planaria.
Epinephrine, ephedrine, dopamine and isoproterenol considerably influence carbohydrate utilization in planaria. Dopamine alone and in combination is the most potent, while ephedrine the least effective in this respect. The finding of increased responses to combined treatment supports the view of the existence of different receptor sites for the sympathicomimetic drugs. The results substantiate conclusions concerning the phylogenesis of hormone receptors.
D000818:Animals; D004298:Dopamine / Q000494:pharmacology*; D004809:Ephedrine / Q000494:pharmacology*; D004837:Epinephrine / Q000494:pharmacology*; D005947:Glucose / Q000378:metabolism*; D007545:Isoproterenol / Q000494:pharmacology*; D010932:Planarians / Q000187:drug effects* / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism; D014419:Turbellaria / Q000187:drug effects*
D011956:Receptors, Cell Surface; D004809:Ephedrine; D005947:Glucose; D007545:Isoproterenol; D004298:Dopamine; D004837:Epinephrine