[Histological study of the bone marrow in 96 cases of Waldenstrom's macroglobulinemia. An evaluation with clinical, haematological and biological data (author's transl)].
Bone marrow biopsy in Waldenstrom's macroglobulinemia shows three types of lesions: lympho-plasmocytic and reticular infiltration, which is the most common, reticular infiltration, and aplastic marrow, more seldom. In all cases the reticulinic network is increased and thickened. These lesions are diffuse or nodular. Diffuse infiltration is more severe and has a median duration of 62 months instead of 82 months in nodular infiltration.
D000367:Age Factors; D000368:Aged; D001798:Blood Proteins / Q000032:analysis; D001799:Blood Sedimentation; D001847:Bone Diseases / Q000209:etiology; D001853:Bone Marrow / Q000473:pathology*; D001855:Bone Marrow Diseases / Q000209:etiology; D003094:Collagen / Q000032:analysis; D003238:Connective Tissue / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis; D012155:Reticulin / Q000032:analysis; D012509:Sarcoma / Q000209:etiology; D012737:Sex Factors; D008258:Waldenstrom Macroglobulinemia / Q000097:blood / Q000150:complications / Q000401:mortality / Q000473:pathology*
D001798:Blood Proteins; D012155:Reticulin; D003094:Collagen
Etude histologique de la moelle osseuse dans 96 cas de maladie de Waldenström. Confrontation avec les données cliniques, hématologiques et biologiques.