title: Studies in epidemiology of maedi/visna in sheep.
abstract: Lambs born to ewes from flocks with a high incidence of maedi/visna were separated from their dams at birth (group 1), or after 10 h (group 2), six weeks (group 3) or one year (group 4) and were observed for periods of up to eight years. Group 1 lambs remained free of infection while 28 per cent, 76 per cent and 81 per cent respectively of lambs in the other groups developed clinical, serological or histopathological evidence of infection during the observation period. It is therefore concluded that vertical transmission, if it occurs at all, is of little significance in the epidemiology of the disease. The number of serologically, virologically and histopathologically maedi/visna positive sheep, the time of onset of disease and the severity of lesions were related to the duration of exposure to the parent flock. In a separate trial no evidence was obtained for the transmission of maedi/visna by Muellerius capillaris larvae.
mesh_terms: D000818:Animals; D003168:Complement Fixation Tests; D005260:Female; D008681:Metastrongyloidea / Q000382:microbiology; D011021:Pneumonia, Progressive Interstitial, of Sheep / Q000453:epidemiology* / Q000382:microbiology / Q000635:transmission; D012756:Sheep; D014790:Visna-maedi virus