[The Heidelberg capsule, an antacid of improved galenics].
By means of the Heidelberg capsule the influence of two different antacids on the acidity of gastric juice was measured in 16 normal test subjects. The antacidic combination drugs were Roha salt tablets (RSTB) containing herba absinthii 1.9 mg; fruct. anisi 35.5 mg; rhiz. calami 22.2 mg; bolus alba 14.0 mg; calcium phosphoricum 53.3 mg; magnesium sulfuricum 41.1 mg; calcium carbonicum 70.0 mg; magnesium carbonicum 42.0 mg; sodium bicarbonicum 1120 mg, and Roha gastric tablets (RMTB) with retarded release and containing fruct. anisi 40 mg; herba absinthii 3.2 mg; calcium carbonicum 688 mg; sodium bicarbonicum 480 mg; magnesium carbonicum 40 mg. Compared to the simple antacid RSTB, the duration of the neutralizing effect of the retarded RMTB was prolonged significantly by 300%.
D000328:Adult; D000863:Antacids / Q000494:pharmacology*; D002214:Capsules; D002254:Carbonates / Q000494:pharmacology*; D003692:Delayed-Action Preparations; D005260:Female; D005750:Gastric Juice / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D013678:Technology, Pharmaceutical; D013997:Time Factors
D000863:Antacids; D002214:Capsules; D002254:Carbonates; D003692:Delayed-Action Preparations
Untersuchungen mit der Heidelberger Kapsel an einem galenisch verbesserten Antazidum