title: In vitro hepatic and extra-hepatic reduction of (minus)-nicotine-1'-N-oxide in rats.
mesh_terms: D000693:Anaerobiosis; D000818:Animals; D002248:Carbon Monoxide / Q000494:pharmacology; D002849:Chromatography, Gas; D003497:Cyclic N-Oxides / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004064:Digestive System / Q000378:metabolism; D004386:Duodenum / Q000378:metabolism; D004492:Edetic Acid / Q000494:pharmacology; D005415:Flavins / Q000494:pharmacology; D005753:Gastric Mucosa / Q000378:metabolism; D007082:Ileum / Q000378:metabolism; D066298:In Vitro Techniques; D007422:Intestines / Q000648:ultrastructure; D007668:Kidney / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D008168:Lung / Q000378:metabolism; D008297:Male; D008861:Microsomes / Q000201:enzymology; D008862:Microsomes, Liver / Q000201:enzymology; D008930:Mitochondria, Liver / Q000201:enzymology / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D009247:NADH, NADPH Oxidoreductases / Q000037:antagonists & inhibitors; D009249:NADP; D009538:Nicotine / Q000378:metabolism*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000037:antagonists & inhibitors / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology; D011335:Proadifen / Q000494:pharmacology; D011506:Proteins / Q000378:metabolism; D051381:Rats
chemical_list: D003497:Cyclic N-Oxides; D005415:Flavins; D011506:Proteins; D009249:NADP; D009538:Nicotine; D002248:Carbon Monoxide; D003577:Cytochrome P-450 Enzyme System; D004492:Edetic Acid; D011335:Proadifen; D010088:Oxidoreductases; D009247:NADH, NADPH Oxidoreductases; D010634:Phenobarbital