title: [Correlation of Na,K-ATPase activity and protein synthesis in nerve cell membranes exposed to acetylcholine].
abstract: Acetylcholine (10(-6)--10(-3) M) added to the rat brain homogenate increased that activity of microsomal Na, K-ATPase and (14C)-amino acid incorporation in microsomal proteins. Actinomicin D (5.10(-5) M) eliminated the effect of acetylcholine. It is concluded that acetylcholine induced the synthesis of either Na, K-ATPase itself or some other proteins involved in the enzyme activity regulation.
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004790:Enzyme Induction / Q000187:drug effects; D066298:In Vitro Techniques; D008297:Male; D008861:Microsomes / Q000201:enzymology; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D009441:Neurilemma / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000096:biosynthesis*
chemical_list: D009419:Nerve Tissue Proteins; D000254:Sodium-Potassium-Exchanging ATPase; D000109:Acetylcholine
vernacular_title: Korreliatsiia Na,K-ATFaznoi aktivnosti i sinteza belkov v membranakh nervnykh kletok pri vozdeĭstvii atsetilkholina.