Genetic studies on the Gc subtypes.
Gc subtypes were determined by immunofixation isoelectric focusing. In a family study involving 93 families with a total of 176 children, a three-allele model with six genotypes was confirmed. The distribution of Gc subtypes was studied in three populations from Europe and in a sample of Druzes from Northern Israel. Three new variant Gc types were observed.
D000483:Alleles; D002352:Carrier Proteins / Q000235:genetics*; D002648:Child; D002762:Cholecalciferol / Q000378:metabolism*; D005787:Gene Frequency; D005858:Germany; D006801:Humans; D007525:Isoelectric Focusing; D007557:Israel; D007558:Italy; D011110:Polymorphism, Genetic
D002352:Carrier Proteins; D002762:Cholecalciferol