[Effect of dibazol on the state of the hypophyseal-adrenal system in patients operated on under thiopental anesthesia].
In the observations over the patients subjected to operations on the limbs under thiopental narcosis and in the experiments on white rats exposed to a shockogenic trauma (by Kennon's method) it has been found that the prophylactic injection of 1--2 mg/kg dose of dibazol rises the non-specific resistance of the body. The hormones of the pituitary-adrenal system have been found to hold an important place in the mechanism of the effect of dibazol.
D015062:11-Hydroxycorticosteroids / Q000097:blood; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000818:Animals; D001562:Benzimidazoles / Q000008:administration & dosage*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects; D008297:Male; D009125:Muscle Relaxants, Central / Q000008:administration & dosage*; D010913:Pituitary-Adrenal System / Q000187:drug effects*; D051381:Rats; D012774:Shock, Traumatic / Q000097:blood; D013514:Surgical Procedures, Operative; D013874:Thiopental; D013997:Time Factors
D015062:11-Hydroxycorticosteroids; D001562:Benzimidazoles; D009125:Muscle Relaxants, Central; D000324:Adrenocorticotropic Hormone; D013874:Thiopental
Vliianie dibazola na sostoianie gipofiz-adrenalovoĭ sistemy u bol'nykh, operiruemykh pod tiopentalovym narkozom.