A preliminary investigation of the human pharmacology of a novel azido-pyrimidine diuretic, SC 16102.
D000284:Administration, Oral; D001386:Azides / Q000494:pharmacology; D004231:Diuresis; D004232:Diuretics / Q000008:administration & dosage / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D006852:Hydrochlorothiazide / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D007687:Kidney Tubules, Proximal / Q000187:drug effects; D008297:Male; D000451:Mineralocorticoid Receptor Antagonists; D009318:Natriuresis; D011188:Potassium / Q000378:metabolism; D011743:Pyrimidines / Q000494:pharmacology*; D013997:Time Factors; D014667:Vasopressins / Q000037:antagonists & inhibitors; D014868:Water Deprivation
D001386:Azides; D004232:Diuretics; D000451:Mineralocorticoid Receptor Antagonists; D011743:Pyrimidines; D006852:Hydrochlorothiazide; D014667:Vasopressins; D011188:Potassium