title: Effects of avian reovirus on Marek's disease (MD). I. Suppression of MD development.
abstract: The effects of an avian reovirus on the development of acute Marek's disease (MD) were studied by exposing chickens to Reo-W isolant of avian reovirus before infecting them with an oncogenic MD herpesvirus (MDHV). Four separate trials were made in a similar manner, 2 trials with an experimental line of White Leghorn (WSU-VS) highly susceptible to MD, and 2 trials with a commercial strain of meat-type (C-MT) chicken. MD mortality and/or incidence of gross MD lesions were consistently reduced by preexposure to avian reovirus. The suppression was more apparent in the WSU-VS than in the C-MT birds, and appeared greater with exposure to reovirus via the respiratory route than with the alimentary route.
mesh_terms: D000818:Animals; D002645:Chickens; D008381:Herpesvirus 2, Gallid / Q000276:immunology; D007167:Immunotherapy; D008380:Marek Disease / Q000276:immunology* / Q000517:prevention & control; D012088:Reoviridae Infections / Q000276:immunology*