Glaucoma and expulsive hemorrhage mechanisms in the Sturge-Weber syndrome.
An eye from an adult with Sturge-Weber syndrome and glaucoma is described histologically following enucleation for massive choroidal hemorrhage. The specimen is noted to contain hemangiomas of the episclera and choroid as well as a partial angle cleavage abnormality. Histologic evidence reviewed herein supports the concept that infantile glaucoma associated with this syndrome may be associated with marked filtration angle cleavage deformities. Some Sturge-Weber patients who develop unilateral glaucoma later as juveniles or adults appear to have milder expressions of angle cleavage abnormality or a forme fruste of this angle disorder. Any surgical procedure for this glaucoma preferably should be one which minimizes or eliminates operative hypotony, thus avoiding a possible expulsive hemorrhage.
D000328:Adult; D002832:Choroid Hemorrhage / Q000473:pathology*; D002830:Choroid Neoplasms / Q000473:pathology; D015353:Eye Enucleation; D005901:Glaucoma / Q000473:pathology*; D006392:Hemangioma, Cavernous / Q000473:pathology; D006801:Humans; D008297:Male; D015422:Scleral Diseases / Q000473:pathology; D013341:Sturge-Weber Syndrome / Q000473:pathology*