Substrate activities for adenosine kinase and adenosine deaminase in relation to the cytotoxicities of some O6-alkyl derivatives of 8-azainosine and 8-azaguanosine.
D000243:Adenosine Deaminase / Q000378:metabolism*; D000248:Adenosine Kinase / Q000378:metabolism*; D001372:Aza Compounds / Q000378:metabolism / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects*; D006151:Guanosine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D007288:Inosine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D007700:Kinetics; D009700:Nucleoside Deaminases / Q000378:metabolism*; D010770:Phosphotransferases / Q000378:metabolism*
D001372:Aza Compounds; D006151:Guanosine; D007288:Inosine; D010770:Phosphotransferases; D000248:Adenosine Kinase; D009700:Nucleoside Deaminases; D000243:Adenosine Deaminase