[Modification of a method to study cell fusion induced in vitro by viruses].
A studying method of viruses induced cell-fusion is described, using monolayers of Vero monkey cells. Nature and density of cells and infection multiplicity are studied. The sensibility is equal to 4 hemagglutining units of Sendaï and accuracy about +/- 3 % of polykaryocytosis. Quantification. comparison and kinetics study of cell-fusion are allowed by this method which may lead to systematic and routine exploration of cell-fusion ability of biological extracts from slow degenerative diseases of the human central nervous system.
D000818:Animals; D002459:Cell Fusion / Q000187:drug effects; D002478:Cells, Cultured; D006224:Cricetinae; D003584:Cytological Techniques; D000882:Haplorhini; D006801:Humans; D008459:Measles virus; D051379:Mice; D010222:Parainfluenza Virus 1, Human; D011092:Polyethylene Glycols / Q000494:pharmacology; D012756:Sheep; D014790:Visna-maedi virus
D011092:Polyethylene Glycols
Mise au point d'une méthode d'étude de la fusion cellulaire induite in vitro par les virus.