[Acute nephritis and allergic vasculitis due to phenindione (author's transl)].
The authors report a case of acute nephritis which appears during a treatment with phenindione. The nephropathy described after this medication are now well known. Their manifestations are either a proteinuria associated or not with a nephrotic syndrome or an interstitial nephritis whose pronostic is reserved. In this observation the mechanism is different : the lesion is glomerular and complicates an allergic vasculitis which was secondary to the phenindione's therapy. The pronostic was good.
D000208:Acute Disease; D000368:Aged; D000936:Antigen-Antibody Complex; D004342:Drug Hypersensitivity / Q000209:etiology*; D005921:Glomerulonephritis / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D010630:Phenindione / Q000009:adverse effects*; D014657:Vasculitis / Q000139:chemically induced* / Q000276:immunology
D000936:Antigen-Antibody Complex; D010630:Phenindione
Glomérulonéphrite aiguë et vascularite allergique après traitement a la phénylindanedione.