Hepatitis A infection and primary hepatocellular carcinoma.
The prevalence of antibody to the hepatitis A antigen (anti-HAV) has been studied in Senegal, among patients suffering from primary hepatocellular carcinoma (PHC) and among healthy blood donors. Anti-HAV was found in 62.5% of 64 cases of PHC as compared to 64% of 50 blood donors. Anti-HAV was as prevalent among PHC patients who evidenced chronic hepatitis B infection as among those without markers of chronic hepatitis B infection. These data suggest that hepatitis A infection is not associated with PHC in Senegal.
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D006528:Carcinoma, Hepatocellular / Q000209:etiology* / Q000276:immunology; D005260:Female; D006506:Hepatitis A / Q000150:complications* / Q000276:immunology; D006509:Hepatitis B / Q000276:immunology; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology* / Q000276:immunology; D008297:Male; D012675:Senegal
D000914:Antibodies, Viral