A major locus for hyper-beta-lipoproteinemia with xanthomatosis.
Complex segregation analysis of hyper-beta-lipoproteinemia with xanthomatosis has provided strong evidence for a major locus, in addition to significant polygenic effect and sibling environment. Estimates of gene frequency agree with values generally given in the literature.
D002874:Chromosome Mapping; D005787:Gene Frequency; D006801:Humans; D006937:Hypercholesterolemia / Q000235:genetics*; D006949:Hyperlipidemias / Q000235:genetics*; D008077:Lipoproteins, LDL / Q000097:blood*; D008954:Models, Biological; D014973:Xanthomatosis / Q000235:genetics*
D008077:Lipoproteins, LDL