Trials of treating myocarditis in mice infected with coxsackie B3 viruses.
On the assumption of an immunologic background of chronic myocarditis after infection with Coxsackie B3 viruses, mice were treated with prednisolone or cyclophosphamide, starting 18 days after infection, for periods of three months. The favorable therapeutic effect indicates that chronic myocarditis is an immunologic disease.
D000818:Animals; D003384:Coxsackievirus Infections / Q000188:drug therapy* / Q000276:immunology; D003520:Cyclophosphamide / Q000627:therapeutic use*; D029822:Enterovirus B, Human; D051379:Mice; D009205:Myocarditis / Q000188:drug therapy* / Q000276:immunology; D011239:Prednisolone / Q000627:therapeutic use*; D013997:Time Factors
D003520:Cyclophosphamide; D011239:Prednisolone