Changes in beta-2 adrenergic receptor sensitivity with maturation of erythroid progenitor cells.
Erythroid burst forming units (BFU-E) were much more sensitive to the beta-2 selective adrenergic drug, salbutamol, than erythroid colony forming units (CFU-E) in an in vitro study of erythroid progenitor cells.
D000420:Albuterol / Q000494:pharmacology; D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000502:physiology*; D002078:Butoxamine / Q000494:pharmacology; D002478:Cells, Cultured; D004921:Erythropoietin / Q000494:pharmacology; D006412:Hematopoietic Stem Cells / Q000187:drug effects / Q000502:physiology*; D011817:Rabbits; D011941:Receptors, Adrenergic / Q000502:physiology*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000502:physiology*
D011941:Receptors, Adrenergic; D011943:Receptors, Adrenergic, beta; D002078:Butoxamine; D004921:Erythropoietin; D000420:Albuterol