Starvation-induced decreased sensitivity of resting metabolic rate to triiodothyronine.
The decrease in resting oxygen consumption induced by starvation was found to occur not only in euthyroid rats but also in hypothyroid and even in hypothyroid animals treated with triiodothyronine. Furthermore, the effectiveness of triiodothyronine was decreased when given to hypothyroid animals.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004734:Energy Metabolism / Q000187:drug effects; D007037:Hypothyroidism / Q000378:metabolism; D008297:Male; D010101:Oxygen Consumption / Q000187:drug effects*; D051381:Rats; D011956:Receptors, Cell Surface / Q000187:drug effects; D013217:Starvation / Q000378:metabolism*; D014284:Triiodothyronine / Q000494:pharmacology*
D011956:Receptors, Cell Surface; D014284:Triiodothyronine