Malignant lymphoma in four of five siblings.
In one family four out of five siblings were affected with malignant lymphoma and HD has been diagnosed in two other relatives. HLA-haplotypes were identical for the three diseased siblings who were so studied, whereas for the unaffected one they were different.
D000914:Antibodies, Viral / Q000032:analysis; D001789:Blood Group Antigens; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006680:HLA Antigens; D004854:Herpesvirus 4, Human / Q000276:immunology; D006689:Hodgkin Disease / Q000235:genetics / Q000276:immunology; D006801:Humans; D008213:Lymphocyte Activation; D008223:Lymphoma / Q000235:genetics* / Q000276:immunology; D008875:Middle Aged; D010375:Pedigree
D000914:Antibodies, Viral; D001789:Blood Group Antigens; D006680:HLA Antigens