title: [Association of scleroderma with primary biliary cirrhosis (author's transl)].
abstract: A new case of Reynold's syndrome is reported. This patient was a 70 years old woman with scleroderma (grade II) and PBC (grade III - IV), associated with Sjögren's syndrome and cryoglobulinemia. She experienced 10 years earlier Raynaud's syndrome and arthralgia. A review of the Literature reveals 22 other detailed cases whose data are collected in this study. Considerations upon a common pathophysiology for scleroderma, PBC and Sjögren's syndrome are developed. Impairment of the function of suppressor T cells in patients undergoing these diseases is possible.
mesh_terms: D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000032:analysis; D003450:Cryoglobulins / Q000032:analysis; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007592:Joint Diseases / Q000209:etiology; D008105:Liver Cirrhosis, Biliary / Q000276:immunology* / Q000473:pathology; D008875:Middle Aged; D011928:Raynaud Disease / Q000209:etiology; D012595:Scleroderma, Systemic / Q000276:immunology* / Q000473:pathology; D012859:Sjogren's Syndrome / Q000150:complications / Q000276:immunology; D013577:Syndrome; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D001323:Autoantibodies; D003450:Cryoglobulins; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Association de sclérodermie et de cirrhose biliaire primitive.