title: Triplex gene dosage effect of TPI and G3PD in a human lymphoblastoid cell line with partial trisomy 12p13 and 18p.
abstract: The EBV-induced lymphoblastoid line established from a patient carrying a duplication of the distal part of chromosome 12 short arm (12p13) retained the original partial trisomy and displayed the same triplex gene dosage effect for TPI and G3PD as found in the patient's RBC and WBC.
mesh_terms: D002238:Carbohydrate Epimerases / Q000235:genetics*; D002460:Cell Line; D002472:Cell Transformation, Viral; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases / Q000235:genetics*; D004854:Herpesvirus 4, Human; D006801:Humans; D014305:Triose-Phosphate Isomerase / Q000235:genetics*; D014314:Trisomy
chemical_list: D005987:Glyceraldehyde-3-Phosphate Dehydrogenases; D002238:Carbohydrate Epimerases; D014305:Triose-Phosphate Isomerase