[Adrenocortical function in hyperprolactinemia. The study of glucocorticoids, mineralocorticoids and androgens in chronic and acute hyperprolactinemias (author's transl)].
Glucocorticoids, mineralocorticoids, and adrenal androgens were studied in 3 groups of patients: control subjects (group I), hyperprolactinemic subjects (group II) and miscellaneous patients including chromophobe adenomas and normalized hyperprolactinemic subjects treated with Bromocriptine (group III). All the patients were studied in the basal state and under various conditions: Metyrapone, ACTH, TRH for glucocorticoids, ACTH, TRH, saline perfusion for mineralocorticoids, ACTH and TRH for androgens. It is concluded that: the adrenal secretion of glucocorticoids, mineralocorticoids and androgens is not altered under basal conditions in chronic hyperprolactinemia nor during dynamic tests in chronic hyperprolactinemia (prolactin adenoma) nor in acute hyperprolactinemia (induced by TRH).
D000208:Acute Disease; D000236:Adenoma / Q000097:blood; D000302:Adrenal Cortex / Q000502:physiology*; D000324:Adrenocorticotropic Hormone; D000728:Androgens / Q000097:blood*; D002908:Chronic Disease; D005260:Female; D005938:Glucocorticoids / Q000097:blood*; D006801:Humans; D008797:Metyrapone; D008901:Mineralocorticoids / Q000097:blood*; D010911:Pituitary Neoplasms / Q000097:blood; D011388:Prolactin / Q000097:blood*; D013973:Thyrotropin-Releasing Hormone
D000728:Androgens; D005938:Glucocorticoids; D008901:Mineralocorticoids; D013973:Thyrotropin-Releasing Hormone; D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D008797:Metyrapone
La fonction cortico-surrénale dans les hyperprolactinémies. Etude des glucocorticoïdes, minéralocorticoïdes, et androgènes dans les états d'hyperprolactinémie aiguë et chronique.