Sites including those of origin and termination of replication are not freely available to single-cut restriction endonucleases in the supercompact form of simian virus 40 minichromosome.
D002460:Cell Line; D002843:Chromatin; D004261:DNA Replication; D004262:DNA Restriction Enzymes; D004278:DNA, Superhelical / Q000378:metabolism; D004279:DNA, Viral / Q000378:metabolism; D005814:Genes, Viral; D008854:Microscopy, Electron; D013539:Simian virus 40 / Q000378:metabolism*
D002843:Chromatin; D004278:DNA, Superhelical; D004279:DNA, Viral; D004262:DNA Restriction Enzymes