Identification of flurazepam (Dalmane) and a primary metabolite in urine by thin-layer chromatography.
A relatively simple, routine method has been described for the qualitative identification of flurazepam and its primary metabolite 7-chloro-1-(2-hydroxyethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one in urine. We have described two extractions and several identification procedures by which flurazepam and its primary urinary metabolite can be identified by TLC.
D014151:Anti-Anxiety Agents / Q000652:urine*; D001570:Benzodiazepinones / Q000652:urine; D002855:Chromatography, Thin Layer / Q000379:methods; D005479:Flurazepam / Q000031:analogs & derivatives / Q000378:metabolism / Q000652:urine*; D006801:Humans
D014151:Anti-Anxiety Agents; D001570:Benzodiazepinones; D005479:Flurazepam