Nucleotide sequence of the self-priming 3' terminus of the single-stranded DNA extracted from the parvovirus Kilham rat virus.
The parvovirus genome is a linear, single-stranded DNA molecule with double-stranded hairpin termini. The 3' terminus can serve in vitro as a self-primer for the synthesis of a double-stranded viral DNA intermediate. We have sequenced the nucleotides in the 3' terminus and propose a model for the secondary structure of the terminus and the in vitro origin of replication for the complementary viral DNA strand.
D001483:Base Sequence; D003090:Coliphages / Q000201:enzymology; D004277:DNA, Single-Stranded / Q000032:analysis*; D004279:DNA, Viral / Q000032:analysis*; D004259:DNA-Directed DNA Polymerase / Q000378:metabolism; D009711:Nucleotides / Q000032:analysis*; D010321:Parvoviridae / Q000032:analysis*; D017992:Parvovirus / Q000032:analysis*
D004277:DNA, Single-Stranded; D004279:DNA, Viral; D009711:Nucleotides; D004259:DNA-Directed DNA Polymerase