Renal function studies using 99mTc-dimercaptosuccinic acid.
99mTc-dimercaptosuccinic acid (DMSA), provides both a well defined renal image via preferential cortical accumulation, and a quantitative assessment of separate kidney function, correlating well with renal plasma flow obtained from the 131I-Hippuran renogram of each kidney. 99mTc-DMSA is capable of labeling the functioning nephrons in the cortex without interference by the activity of urine flow, suggesting that DMSA should be termed a cortical tubular marker. 99mTc-DMSA scintigraphy has advantages over conventional methods in that it can be performed repeatedly with little discomfort to the patients, as a routine clinical examination.
D002648:Child; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging* / Q000378:metabolism; D007677:Kidney Function Tests / Q000379:methods*; D011877:Radionuclide Imaging; D004113:Succimer / Q000378:metabolism; D013438:Sulfhydryl Compounds; D013667:Technetium / Q000378:metabolism
D013438:Sulfhydryl Compounds; D013667:Technetium; D004113:Succimer