[Changes in the proliferative response of human lymphocytes in vitro on exposure to subcellular components of Bordetella pertussis].
Different components of B. pertussis were found to have a similar inhibitory effect on thymidine-3H incorporation caused by phytohemagglutinin (PHA) in the culture of lymphocytes taken from donors immunized with tetanus toxoid. However, the same fractions of B. pertussis produced differential effects on the reaction of lymphocyte proliferation in response to tetanus toxoid: murein-"ontaining membranes enhanced thymidine-3H incorporation, RNA-containing fractions reduced it and water-soluble components of disintegrated B. pertussis produced no effect on lymphocyte proliferation.
D001886:Bordetella pertussis / Q000276:immunology*; D004247:DNA / Q000096:biosynthesis; D006801:Humans; D066298:In Vitro Techniques; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D010835:Phytohemagglutinins / Q000276:immunology; D013347:Subcellular Fractions / Q000276:immunology*; D013745:Tetanus Toxoid / Q000276:immunology
D010835:Phytohemagglutinins; D013745:Tetanus Toxoid; D004247:DNA
Izmeneniia proliferativnogo otveta limfotsitov cheloveka in vitro pod deĭstviem subkletochnykh komponentov kokliushnykh bakteriĭ.