title: Radiation-induced aldehydes in collagen.
abstract: Aldehydes present in native and irradiated (30 krad) collagen were separated from its enzymic degradation products using molecular-sieve chromatography on Bio-Gel P-2 column. From the absorption spectra of N-methylbenzothiazolone hydrazone derivatives it was concluded that two out of five of the aldehydes separated from the irradiated collagen, were identical with those present in control collagen. The possible origin of three other aldehydes is discussed.
mesh_terms: D000447:Aldehydes / Q000138:chemical synthesis*; D000818:Animals; D002850:Chromatography, Gel; D003094:Collagen / Q000031:analogs & derivatives / Q000528:radiation effects*; D006835:Hydrazones; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D003012:Microbial Collagenase; D011830:Radiation Effects; D051381:Rats; D013057:Spectrum Analysis; D013844:Thiazoles; D014965:X-Rays
chemical_list: D000447:Aldehydes; D006835:Hydrazones; D013844:Thiazoles; D003094:Collagen; D003012:Microbial Collagenase