Dopamine blockade of the thyroliberin -- induced cyclic AMP accumulation in rat anterior pituitary.
Effects of dopamine and thyroliberin on the cyclic AMP concentration in the rat anterior pituitary gland were investigated in vitro. Dopamine by itself had no effect on the anterior pituitary cAMP concentration but inhibited the cAMP-accumulating effect of thyroliberin.
D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D004298:Dopamine / Q000494:pharmacology*; D008297:Male; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000378:metabolism*; D051381:Rats; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology*
D013973:Thyrotropin-Releasing Hormone; D000242:Cyclic AMP; D004298:Dopamine