title: [Etiology of combined inhalational hydrocyanic acid and carbon monoxide poisoning].
abstract: A young man was found dead in a kitchen, that was partly burnt. Autopsy revealed, as cause of death, a combined intoxication following inhalation of carbon monoxide and hydrocyanic acid. Own investigations on the pyrolysis of pieces of furniture found in the kitchen (plastic plates containing melamine and plates containing formaldehyde) showed, that hydrocyanic acid was liberated through combustion of such substances and inhaled by the victim. The poisoning picture is discussed, and discussion includes especially considerations on the peculiar sensitivity of the brain toward the action of hydrocyanic acid and the relative insensitivity of the heart muscle. It is thought that the cause of such sensitivity difference lies in the physiological differences of the intracellular energy production. Finally the dangers of combustion gases developing from burning plastic materials are reemphasized.
mesh_terms: D000328:Adult; D001344:Autopsy; D002248:Carbon Monoxide / Q000032:analysis; D002249:Carbon Monoxide Poisoning / Q000209:etiology* / Q000473:pathology; D004347:Drug Interactions; D004781:Environmental Exposure; D005390:Fires; D006801:Humans; D006856:Hydrogen Cyanide / Q000032:analysis / Q000506:poisoning*; D008297:Male
chemical_list: D006856:Hydrogen Cyanide; D002248:Carbon Monoxide
vernacular_title: Zur Entstehung der kombinierten inhalatorischen Blausäure-Kohlenmonoxid-Vergiftung.