title: The penetration of the embedding medium methyl methacrylate in undecalcified bone.
abstract: Cutting artifacts in microtome sections prepared from undemineralized methyl methacrylate embedded bone are due to the almost complete absence of methacrylate in the intercellular compartment of the bone tissue, the soft tissues being fully impregnated with the polymer. The osteocyte system is only partially penetrated by methacrylate.
mesh_terms: D001842:Bone and Bones / Q000187:drug effects / Q000648:ultrastructure*; D004492:Edetic Acid / Q000494:pharmacology; D006652:Histological Techniques; D006801:Humans; D008768:Methylmethacrylates / Q000302:isolation & purification; D003012:Microbial Collagenase / Q000494:pharmacology; D008855:Microscopy, Electron, Scanning; D014357:Trypsin / Q000494:pharmacology
chemical_list: D008768:Methylmethacrylates; D004492:Edetic Acid; D014357:Trypsin; D003012:Microbial Collagenase