Influence of alterations in meal frequency on lipogenesis and body fat content in the rat.
Rats were allowed to eat only 2 hr per day (meal-fed) or were fed ad libitum (nibbler) for 12 wk; another group of animals was meal-fed for 3 wk and then fed ad libitum (converted I) while the fourth group of rats (converted II) was meal-fed for 3 wk, allowed to nibble for the next 3 wk, meal-fed from the 6th to 9th wk and then returned to ad libitum feeding for the last 3 wk. Body fat gain and food efficiency was increased in converted I rats. The lipogenic capacity of adipose tissue from meal-fed rats was greater than observen meal-fed rats were reverted to ad libitum feeding whereas lipogenic activity increased rapidly when ad libitum fed rats were switched to meal-feeding.
D000103:Acetyl-CoA Carboxylase / Q000032:analysis; D000273:Adipose Tissue / Q000032:analysis* / Q000201:enzymology; D000818:Animals; D001835:Body Weight; D064429:Fatty Acid Synthases / Q000032:analysis; D005227:Fatty Acids / Q000096:biosynthesis*; D005247:Feeding Behavior; D005508:Food Deprivation; D008297:Male; D051381:Rats; D013997:Time Factors
D005227:Fatty Acids; D064429:Fatty Acid Synthases; D000103:Acetyl-CoA Carboxylase