title: [Sleep stages and growth hormone in manganese poisoning. Effects of L dopa].
abstract: Sleep characteristics are studied in 7 patients with sequelae of manganese intoxication and in 8 controls. A reduction in the length of the REM stage was observed, which could be prolonged by L Dopa administration, but without achieving values comparable to the controls. No changes were noted in the non-REM stage of sleep. These results are similar to the ones obtained in Parkinson's disease, suggesting clinical and probably biochemical similarities between the 2 conditions. The blood concentrations of growth hormone during sleep in the manganic patients was lower than in the control group, and no significant variations were noted after L Dopa administration.
mesh_terms: D000328:Adult; D000368:Aged; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D007980:Levodopa / Q000494:pharmacology* / Q000627:therapeutic use; D020149:Manganese Poisoning; D008875:Middle Aged; D012895:Sleep, REM / Q000187:drug effects
chemical_list: D007980:Levodopa; D013006:Growth Hormone
vernacular_title: Etapas de sueño y hormona de crecimiento en intoxicación por manganeso. Efecto de L Dopa.