[Prostaglandin E binding by plasmatic membranes of thyroid gland cells].
The binding of prostaglandins E (PGE) with human and bovine thyrocyte plasmatic membranes was investigated by the new method with material from the kit for radioimmunoassay of PGE. There was a high affinity and a low affinity site for the specific PGE binding on human and bovine thyrocytes plasmic membranes. The effect of thyrotropin and cyclic nucleotides on the PGE binding by the membranes was revealed.
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000818:Animals; D002417:Cattle; D002462:Cell Membrane / Q000378:metabolism*; D006152:Cyclic GMP / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D006044:Goiter, Nodular / Q000378:metabolism; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism; D009829:Oleic Acids / Q000494:pharmacology; D011458:Prostaglandins E / Q000378:metabolism*; D011485:Protein Binding / Q000187:drug effects; D013961:Thyroid Gland / Q000378:metabolism*; D013972:Thyrotropin / Q000494:pharmacology
D008565:Membrane Proteins; D009829:Oleic Acids; D011458:Prostaglandins E; D000324:Adrenocorticotropic Hormone; D013972:Thyrotropin; D006152:Cyclic GMP
Sviazyvanie prostaglandinov E plazmaticheskimi membranani kletok shchitovidnoi zhelezy.