[Effect of adaptation to high-altitude hypoxia on the adrenoreactivity of the heart and the state of the adenyl cyclase and phosphodiesterase systems of the myocardium].
Experiments in white rats suggested that changes in activity of certain intracellular systems played a significant role in the mechanism of increasing adrenoreactivity of the heart in adaptation to high-altitude hypoxia.
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000378:metabolism; D000064:Acclimatization; D000262:Adenylyl Cyclases / Q000378:metabolism; D000531:Altitude; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism; D006321:Heart / Q000187:drug effects / Q000503:physiopathology*; D000860:Hypoxia / Q000201:enzymology / Q000503:physiopathology*; D007527:Isoenzymes / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000201:enzymology*; D009638:Norepinephrine / Q000494:pharmacology; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D051381:Rats
D007527:Isoenzymes; D000242:Cyclic AMP; D010727:Phosphoric Diester Hydrolases; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D000262:Adenylyl Cyclases; D009638:Norepinephrine
Vliianie adaptatsii k vysotnoĭ gipoksii na adrenoreaktivnost' serdtsa i sostoianie adeniltsiklaznoĭ i fosfodiésteraznoĭ sistem miokarda.