The effect of drug therapy without volume restoration in experimental traumatic shock. Part II. Pethidine.
Different opinions seem to exist as to the use of analgesies in the treatment of trauma patients. For this reason we investigated experimentally the effect of pethidine in traumatic shock. Pethidine was administrated to eight of sixteen anaesthetized rabbits with lower limb injuries. The effect of pethidine was unfavourable. This was due to the effect of the drug on circulation and not on respiration.
D000818:Animals; D001794:Blood Pressure; D001810:Blood Volume; D005260:Female; D006400:Hematocrit; D006863:Hydrogen-Ion Concentration; D008297:Male; D008614:Meperidine / Q000627:therapeutic use*; D010313:Partial Pressure; D011817:Rabbits; D012774:Shock, Traumatic / Q000188:drug therapy*; D013997:Time Factors
D008614:Meperidine