title: [Relation of urinary excretion of cholesterol in cancer patients to certain hormonal-metabolic parameters and the effect of drugs on this relation].
abstract: Excretion of cholesterol with urine was studied using gas chromatography in healthy persons, in patients with cancer of mammary glands, fibroadenoma, lung carcinoma and in patients with beningn processes in lungs. Cholesterol excretion was not increased in patients with the malignant tumors studied. In patients with the cancer of mammary glands and lung carcinoma normal correlation was altered between excretion of cholesterol with urine and content of lipoproteins, protein-bound iodine, 11-hydroxycorticosteroids in blood as well as excretion of cyclic AMP with urine. Treatment with euphylline was accompanied by a decrease in cholesteroluria in patients with fibroadenoma but the drug had no comparable effect on patients with the cancer of mammary glands. In patients with the cancer of mammary glands phenphormine caused distinct decrease and misclerone--moderate increase in excretion of cholesterol with urine.
mesh_terms: D015062:11-Hydroxycorticosteroids / Q000097:blood; D015065:17-Hydroxycorticosteroids / Q000652:urine; D000232:Adenofibroma / Q000097:blood / Q000652:urine*; D000628:Aminophylline / Q000494:pharmacology; D000924:Anticholesteremic Agents / Q000494:pharmacology; D001798:Blood Proteins / Q000378:metabolism; D001943:Breast Neoplasms / Q000097:blood / Q000652:urine*; D002784:Cholesterol / Q000097:blood / Q000652:urine*; D000242:Cyclic AMP / Q000652:urine; D005260:Female; D006801:Humans; D007455:Iodine / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D008175:Lung Neoplasms / Q000097:blood / Q000652:urine*; D008297:Male; D008875:Middle Aged; D010629:Phenformin / Q000494:pharmacology; D010743:Phospholipids / Q000097:blood
chemical_list: D015062:11-Hydroxycorticosteroids; D015065:17-Hydroxycorticosteroids; D000924:Anticholesteremic Agents; D001798:Blood Proteins; D008074:Lipoproteins; D010743:Phospholipids; D000628:Aminophylline; D007455:Iodine; D002784:Cholesterol; D010629:Phenformin; D000242:Cyclic AMP
vernacular_title: Vzaimosviaz' ékskretsii kholesterina s mochoĭ u onkologicheskikh bol'nykh s nekotorymi gormonal'no-metabolicheskimi parametrami i vliianie na étot protsess lekarstvennykh preparatov.