Effects of a human plasma fraction on leucocyte migration into inflammatory exudates.
A fraction prepared from normal human plasma inhibits the migration of polymorphonuclear and mononuclear leucocytes into inflammatory exudates produced by the intrapleural injection of carrageeman or turpentine by the subcutaneous implantation of polyvinyl sponges in the rat. The mechanism of the effect does not involve complement depletion.
D000818:Animals; D001798:Blood Proteins / Q000378:metabolism; D002351:Carrageenan; D002464:Cell Migration Inhibition; D003165:Complement System Proteins / Q000032:analysis; D005122:Exudates and Transudates / Q000503:physiopathology*; D005260:Female; D006168:Guinea Pigs; D007249:Inflammation / Q000139:chemically induced / Q000503:physiopathology*; D007962:Leukocytes / Q000187:drug effects*; D010949:Plasma; D010994:Pleura / Q000503:physiopathology; D051381:Rats; D014020:Tissue Extracts / Q000494:pharmacology*
D001798:Blood Proteins; D014020:Tissue Extracts; D002351:Carrageenan; D003165:Complement System Proteins