title: Combined treatment of radioresistant malignant tumors with high frequency hyperthermia and gamma-rays therapy--recent results.
abstract: From the beginning of radiotherapy, efforts have been made to improve the therapeutic effects X-rays by heat. Recently, the combined therapy of heat and X-ray therapy has gained new interest because of failures of the megavoltage therapy of solid malignant tumors. Encouraged by our own animal experiments with a Walker-tumor of rats, since 1972 we have treated 52 patients with tumors of lower sensitivity. We used decimeter waves; wave length of 69 cm and a frequency of 433.92 MHz. After preheating for 3 to 5 min we added the gamma-rays of Caesium-137 or Cobalt-60 in usual rhythms. The total dose only in few cases exceeded 6000 to 6500 rads in six to seven weeks. We observed a relatively very good response for tumors of low sensitivity. The dose was between 20 and 30% lower which in the treatment of tumors of median sensitivity is acceptable. Local recurrences are rare and occurrence of distant metastases are within the characteristic development of certain malignant tumors. A prospective study has begun.
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary / Q000628:therapy; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary / Q000628:therapy; D001943:Breast Neoplasms / Q000628:therapy; D002081:Buttocks; D003528:Carcinoma, Adenoid Cystic / Q000628:therapy; D002588:Cesium Radioisotopes / Q000627:therapeutic use*; D003037:Cobalt Radioisotopes / Q000627:therapeutic use*; D003972:Diathermy; D005260:Female; D005720:Gamma Rays; D006394:Hemangiosarcoma / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000628:therapy*; D011867:Radioisotope Teletherapy; D012888:Skull Neoplasms / Q000628:therapy
chemical_list: D002588:Cesium Radioisotopes; D003037:Cobalt Radioisotopes