Phloretin and related compounds inhibit agonist stimulated cAMP accumulation in cultured cells of CNS origin.
D000241:Adenosine / Q000494:pharmacology; D000818:Animals; D001254:Astrocytoma / Q000378:metabolism; D002478:Cells, Cultured; D002490:Central Nervous System / Q000187:drug effects / Q000378:metabolism*; D000242:Cyclic AMP / Q000378:metabolism*; D006027:Glycosides / Q000378:metabolism; D006801:Humans; D007545:Isoproterenol / Q000494:pharmacology; D051379:Mice; D009447:Neuroblastoma / Q000378:metabolism; D010693:Phloretin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D011458:Prostaglandins E / Q000378:metabolism
D006027:Glycosides; D011458:Prostaglandins E; D000242:Cyclic AMP; D000241:Adenosine; D007545:Isoproterenol; D010693:Phloretin