[Prognostic significance of the cyclic AMP concentration in acute leukemias].
In patients with acute leukemia (myeloblastic, lymphoblastic, undifferentiated) proliferation kinetics and cyclic adenosine-3', 5'-monophosphate (cAMP) concentration of the leukemic cells were studied for their significance in the prediction of responsiveness to cytostatic therapy. Patients with good clinical response had significantly faster turnover and lower cAMP-levels than those who failed to respond to treatment.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001854:Bone Marrow Cells; D002453:Cell Cycle; D000242:Cyclic AMP / Q000097:blood*; D006801:Humans; D007938:Leukemia / Q000097:blood*; D008875:Middle Aged; D011379:Prognosis
D000242:Cyclic AMP
Prognostische Bedeutung der Konzentration von zyklischem AMP bei akuten Leukämien.