title: A brush-border-bound peptidase and amino acid transport.
abstract: Aminopeptidase when in its integral form interacts with lecithin to form a stable lipoprotein complex. The reconstituted system is a single-bilayer vesicle about 30 nm in diameter. The hydrophobic part of the amphipathic hydrolase is incorporated in the lecithin bilayer with the portion carrying enzymic activity oriented towards the external aqueous phase. This part can be detached by proteases.
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D000626:Aminopeptidases / Q000378:metabolism; D000818:Animals; D001692:Biological Transport; D002462:Cell Membrane / Q000201:enzymology*; D004150:Dipeptidases / Q000378:metabolism; D007421:Intestine, Small / Q000201:enzymology; D007700:Kinetics; D008074:Lipoproteins; D008567:Membranes, Artificial; D008871:Microvilli / Q000201:enzymology*; D008954:Models, Biological; D010713:Phosphatidylcholines
chemical_list: D000596:Amino Acids; D008074:Lipoproteins; D008567:Membranes, Artificial; D010713:Phosphatidylcholines; D000626:Aminopeptidases; D004150:Dipeptidases