Characterization of immunofluorescent cyclic GMP-positive fibres in the central nervous system.
The cyclic GMP immunofluorescent fibres in the rat central nervous system have been characterized as processes of fibrous astrocytes, on the basis of distribution and similarity to the localization of glial fibrillary acidic protein. The neuroglial localization of the nucleotide is discussed together with the surprising observation that these cyclic GMP positive fibres are absent from the central nervous system of the adult mouse.
D000818:Animals; D001253:Astrocytes / Q000032:analysis; D001923:Brain Chemistry; D006152:Cyclic GMP / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D005904:Glial Fibrillary Acidic Protein; D051379:Mice; D009412:Nerve Fibers / Q000032:analysis*; D009419:Nerve Tissue Proteins / Q000032:analysis; D011817:Rabbits; D051381:Rats
D005904:Glial Fibrillary Acidic Protein; D009419:Nerve Tissue Proteins; D006152:Cyclic GMP