title: Serum gamma-glutamyl transpeptidase. Evaluation in screening of hospitalized patients.
abstract: Evaluation in screening of hospitalized patients. Am J Clin Pathol 64: 311-314, 1975. The specificity of the serum gamma-glutamyl transpepidase (GGT) was evaluated by its determination in 1,040 unselected adult inpatients. GGT was elevated in 139 (13.4%) patients, but was only rarely elevated in the absence of elevation of other enzymes in the routine chemistry profile. Of the elevations, 32.4% occurred in patients with primary hepatobiliary disease. An elevated serum GGT is a strong indicator of hepatobiliary dysfunction. However, proper interpretation of a serum GGT elevation requires correlation with clinical data and other tests.
mesh_terms: D000437:Alcoholism / Q000175:diagnosis; D001660:Biliary Tract Diseases / Q000175:diagnosis*; D002493:Central Nervous System Diseases / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis; D006505:Hepatitis / Q000175:diagnosis; D006801:Humans; D008103:Liver Cirrhosis / Q000175:diagnosis; D008107:Liver Diseases / Q000175:diagnosis; D008297:Male; D009369:Neoplasms / Q000175:diagnosis; D014947:Wounds and Injuries / Q000175:diagnosis; D005723:gamma-Glutamyltransferase / Q000097:blood*
chemical_list: D005723:gamma-Glutamyltransferase