The role of sodium transport in thyroid thermogenesis.
The hypothesis that augmentation of Na+ transport activity mediates a significant fraction of thyroid thermogenesis is supported by studies on a wide range of target tissues. Recent criticisms based on theoretical and experimental considerations do not appear to negate the validity of this concept. A basic difficulty that remains to be resolved, however, is the development of techniques for assessing the contribution of the Na+ transport pathway to energy turnover in the intact animal.
D000818:Animals; D001833:Body Temperature Regulation; D007037:Hypothyroidism / Q000503:physiopathology; D008099:Liver / Q000378:metabolism; D010101:Oxygen Consumption; D051381:Rats; D012964:Sodium / Q000378:metabolism*; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism; D013696:Temperature; D013961:Thyroid Gland / Q000502:physiology* / Q000503:physiopathology
D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase