Effect of glucosamine on the replication of the arenavirus Junín in Vero cells.
When Vero cells infected with Junín virus are cultured in the presence of 16 mM glucosamine, no infectious virus is produced and no surface antigens or virions are detected. Cytoplasmic viral antigen, however, is synthesized normally.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001116:Arenaviridae / Q000187:drug effects*; D006477:Arenaviruses, New World / Q000187:drug effects* / Q000254:growth & development / Q000276:immunology; D002460:Cell Line; D002467:Cell Nucleus / Q000276:immunology; D003593:Cytoplasm / Q000276:immunology; D005944:Glucosamine / Q000494:pharmacology*; D000882:Haplorhini; D007668:Kidney; D014779:Virus Replication / Q000187:drug effects*
D000956:Antigens, Viral; D005944:Glucosamine