Effect of antipain on radiation induction of endogenous type-C virus from mouse cells in vitro.
Xenotropic murine type-C virus was induced after X-ray or UV light irradiation of K-Balb cells. The induction was markedly suppressed by postirradiation treatment of the cells with antipain, a protease inhibitor of microbial origin. Virus expression was unaffected when the cells were treated with halogenated pyrimidines.
D000976:Antipain / Q000494:pharmacology*; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002472:Cell Transformation, Viral; D005347:Fibroblasts; D007708:Kirsten murine sarcoma virus; D009842:Oligopeptides / Q000494:pharmacology*; D012190:Retroviridae / Q000187:drug effects* / Q000254:growth & development / Q000528:radiation effects; D014466:Ultraviolet Rays; D014779:Virus Replication / Q000187:drug effects* / Q000528:radiation effects; D014965:X-Rays
D009842:Oligopeptides; D000976:Antipain