title: Liquoid induced stasis and the generalized Shwartzman reaction. An electron microscopic study in blue foxes.
abstract: The composition of the occlusive material within dilated glomerular capillaries, following intravenous injections of Liquoid in blue foxes, was studied electron microscopically; it was found that it mainly consisted of a debris in which disintegrated red cells constituted the major component. Damaged platelets and necrotic endothelial remnants were other components. These observations were interpreted as a result of glomerular stasis, and it was concluded that stasis in glomerular capillaries is a basic event in the development of the renal lesions accompanying the generalized Shwartzman reaction.
mesh_terms: D000818:Animals; D005260:Female; D005589:Foxes; D006487:Hemostasis / Q000187:drug effects*; D007678:Kidney Glomerulus / Q000648:ultrastructure*; D008297:Male; D011074:Polyanetholesulfonate / Q000494:pharmacology; D012790:Shwartzman Phenomenon / Q000503:physiopathology*
chemical_list: D011074:Polyanetholesulfonate