[Transfer of genetic information from T to B human lymphocytes during an immune response to herpes simplex virus].
Human blood lymphocytes carrying different allotypes were divided into B and T subpopulations and cultured in presence or in absence of ultraviolet inactivated Herpes Simplex Virus. Isolated B or T cells did not produce any antiherpetic activity. The B lymphocytes cultured in presence of 1 or 50% of the supernatant collected from virus exposed T cells synthesized on antiherpetic antibody with some allotypic markers of the T cell donor.
D000914:Antibodies, Viral / Q000096:biosynthesis*; D001402:B-Lymphocytes / Q000276:immunology*; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000032:analysis / Q000096:biosynthesis*; D066298:In Vitro Techniques; D008211:Lymphocyte Cooperation; D018139:Simplexvirus / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D000914:Antibodies, Viral; D007126:Immunoglobulin Allotypes
Transfert d'informations génétiques de lymphocytes humains T à B au cours d'une réponse immunitaire au virus Herpes simplex.