Depression of spontaneous and ionophore-induced neurotransmitter release by Salmonella.
Exposure of frog neuromuscular junctions to heat-killed, lyophilized Salmonella typhimurium (SR 11) produces an early increase in spontaneous transmitter release followed by depression of release and blockade of the obligatory release usually induced by ionophore X537A.
D000818:Animals; D001001:Anura; D007832:Lasalocid / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects; D009045:Motor Endplate / Q000502:physiology; D009469:Neuromuscular Junction / Q000187:drug effects*; D011894:Rana pipiens; D012475:Salmonella / Q000502:physiology*; D009435:Synaptic Transmission / Q000187:drug effects*
D008070:Lipopolysaccharides; D007832:Lasalocid