Vanadate inhibits (Na+ + K+)ATPase by blocking a conformational change of the unphosphorylated form.
D000818:Animals; D007679:Kidney Medulla / Q000201:enzymology; D008274:Magnesium / Q000494:pharmacology; D010750:Phosphoproteins / Q000037:antagonists & inhibitors; D010766:Phosphorylation; D011487:Protein Conformation / Q000187:drug effects; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors*; D013050:Spectrometry, Fluorescence; D013552:Swine; D014639:Vanadium / Q000494:pharmacology*
D010750:Phosphoproteins; D014639:Vanadium; D000254:Sodium-Potassium-Exchanging ATPase; D008274:Magnesium