Oral contraceptive use and fasting triglyceride, plasma cholesterol and HDL cholesterol.
Fasting plasma triglyceride, plasma cholesterol and high-density lipoprotein (HDL) cholesterol levels were studied for 190 white women, ages 21--39 years, who were classified according to their oral contraceptive (OC) usage patterns at two community surveys, 3 years apart. The mean level of fasting triglyceride was higher among current OC users (95 mg/100 ml) than among nonusers (73 mg/100 ml) (p = 0.002). After adjustment for the possible confounding effects of age, weight, current cigarette smoking and fasting glucose level, current OC users still had a mean plasma triglyceride level 19 mg/100 ml higher than that of nonusers (p = 0.007). Current OC users also appeared to have somewhat higher levels of total cholesterol which were of borderline significance in crude and adjusted analyses. There was a nonsignificant inverse relationship of OC use with HDL cholesterol levels. Past use did not affect these results, indicating that the OC-induced lipid changes were reversible.
D000328:Adult; D000375:Aging; D001786:Blood Glucose; D001835:Body Weight; D002784:Cholesterol / Q000097:blood*; D003276:Contraceptives, Oral; D005260:Female; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood*; D012907:Smoking; D013997:Time Factors; D014280:Triglycerides / Q000097:blood*
D001786:Blood Glucose; D003276:Contraceptives, Oral; D008075:Lipoproteins, HDL; D014280:Triglycerides; D002784:Cholesterol