Metabolic requirements for renal function.
Renal mass accounts for only 0.5% of body weight, yet the kidney consumes 7% of the body's total oxygen uptake. Most is used for tubular transport, but a significant portion contributes to less well-recognized aspects of renal function. Cortical gluconeogenesis capacity, for example, exceeds that of the liver per gram of tissue. Basal and transport metabolic processes are examined in terms of clinical relevance.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D001481:Basal Metabolism; D001693:Biological Transport, Active; D002254:Carbonates / Q000378:metabolism; D005227:Fatty Acids / Q000378:metabolism; D005943:Gluconeogenesis; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007477:Ions / Q000378:metabolism; D007668:Kidney / Q000378:metabolism*; D007679:Kidney Medulla / Q000378:metabolism; D007687:Kidney Tubules, Proximal / Q000378:metabolism; D010455:Peptides / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism
D002254:Carbonates; D005227:Fatty Acids; D007477:Ions; D010455:Peptides; D012964:Sodium; D000251:Adenosine Triphosphatases; D000254:Sodium-Potassium-Exchanging ATPase; D005947:Glucose