title: An out-break of acute gastroenteritis due to rotavirus in an infant home.
abstract: In December 1976, an outbreak of acute infectious diarrhea occurred among infants who resided in an infant home in the city of Sapporo. Rotavirus infection was proved in 42 (90%) of 47 infants by serologic and/or electron microscopic examinations. Out of 42 infected infants 38(90%) were clinically affected; diarrhea with or without vomiting in 27 (64%), vomiting without diarrhea in 6 (14%) and only febrile episode in 5 (12%). The remaining 4(10%) infants showed no symptoms. Clinical manifestations seemed to differ depending on age. Diarrhea without vomiting was more common in the patients younger than 6 months of age, and vomiting or fever was more common in the groups of older age. Possible reasons for such an age dependency were discussed on the basis of complement-fixation tests using human and calf strains of rotavirus.
mesh_terms: D000208:Acute Disease; D000367:Age Factors; D000912:Antibodies, Neoplasm / Q000032:analysis; D004196:Disease Outbreaks / Q000453:epidemiology*; D005759:Gastroenteritis / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D007223:Infant; D007564:Japan; D012112:Residential Facilities; D012401:Rotavirus / Q000276:immunology; D014777:Virus Diseases / Q000453:epidemiology* / Q000276:immunology
chemical_list: D000912:Antibodies, Neoplasm