[Methylprednisolone-induced inhibition of the sympathetic vasomotor tonus in hemorrhagic shock].
In anesthetized cats massive doses of methylprednisolon (40 mg/kg body wt.) induce a blood pressure decrease with bradycardia, which is not transmitted through vagal efferents. These effects are due to an inhibition of sympathetic outflow to heart and vessels.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D002628:Chemoreceptor Cells / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D008775:Methylprednisolone / Q000494:pharmacology*; D011311:Pressoreceptors / Q000187:drug effects; D012771:Shock, Hemorrhagic / Q000503:physiopathology*; D009435:Synaptic Transmission; D014666:Vasomotor System / Q000187:drug effects* / Q000502:physiology
D008775:Methylprednisolone
Methylprednisolon-induzierte Hemmung des sympathischen Vasomotorentonus im hämorrhagischen Schock.