The effect of controlled halothane anaesthesia on splanchnic oxygen consumption in the dog.
The influence of halothane ansesthesia on splanchnic oxygen flow and oxygen uptake was studied in seven dogs. Mean oxygen supply to the liver and the portally-drained tissues decreased significantly to 44% and 53% of control values, respectively, while mena oxygen consumption diminished insignificantly to 68% and 82% of control values, respectively. There was a fall in the oxygen flow/oxygen consumption ratio in all animals following halothane. The relatively unimpaired oxygen uptake, in spite of a diminished oxygen supply, led to an increased extraction of oxygen by the tissues. Some factors affecting oxygen utilisation during halothane anaesthesia are discussed.
D000005:Abdomen; D000758:Anesthesia; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D001831:Body Temperature; D002245:Carbon Dioxide / Q000097:blood; D004285:Dogs; D006221:Halothane / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D008099:Liver / Q000378:metabolism; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption / Q000187:drug effects*; D010313:Partial Pressure; D012039:Regional Blood Flow / Q000187:drug effects; D012119:Respiration
D002245:Carbon Dioxide; D010100:Oxygen; D006221:Halothane