5-Propyl-2'-deoxyuridine: a specific anti-herpes agent.
In both primary rabbit kidney cells and human skin fibroblasts, 5-propyl-2'-deoxyuridine proved inhibitory to herpes simplex virus at a concentration as low as 1 micrograms/ml, whereas concentrations higher than 200 micrograms/ml were required to inhibit vaccinia virus replication or normal cell metabolism.
D000818:Animals; D003857:Deoxyuridine / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D006561:Herpes Simplex / Q000188:drug therapy; D006801:Humans; D011817:Rabbits; D018139:Simplexvirus / Q000187:drug effects*; D014616:Vaccinia virus / Q000187:drug effects
C024068:5-propyl-2'-deoxyuridine; D003857:Deoxyuridine