[Experimental investigations of the content of glycogen in the adrenal gland of the rat after application of dexamethasone, ACTH and a combination of both (author's transl)].
The influence of dexamethasone, ACTH and the combination of both on the glycogen content of the rat adrenal gland was studied. Dexamethasone induces a transient increase of the adrenal glycogen content in a time and dose-dependent manner. The application of ACTH has no effect on the glycogen content. Surprisingly, the increase of the glycogen content induced by dexamethasone is completely blocked by the simultaneous application of ACTH.
D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D003907:Dexamethasone / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006003:Glycogen / Q000378:metabolism*; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D051381:Rats; D013047:Specific Pathogen-Free Organisms; D013997:Time Factors
D008112:Liver Glycogen; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone; D006003:Glycogen
Experimentelle Untersuchungen über den Glykogengehalt der Rattennebenniere nach Gabe von Dexamethason, ACTH sowie der Kombination Dexamethason/ACTH.