title: [Toxicity of silica-gel polymers].
abstract: Mice of the ICR strain were tested for the effect of intraperitoneally applied polymers of silicagel. Silicagel applied in the form of spherical-shaped particles caused local irritation and resorptive reaction with granulocytes. There was also renal damage of the type of necronephrosis and signs of necronephrosis.
mesh_terms: D000818:Animals; D005549:Foreign-Body Reaction; D007274:Injections, Intraperitoneal; D007673:Kidney Cortex Necrosis / Q000139:chemically induced; D051379:Mice; D008813:Mice, Inbred ICR; D011108:Polymers / Q000008:administration & dosage / Q000633:toxicity; D012822:Silicon Dioxide / Q000008:administration & dosage / Q000633:toxicity*; D013997:Time Factors
chemical_list: D011108:Polymers; D012822:Silicon Dioxide
vernacular_title: Toxicita silikagelových polymerů.