title: [Clinical trial of Pulvo 47 Neomycin in the treatment of leg ulcer (author's transl)].
abstract: Pulva 47 Neomycine was tested in 30 patients suffering from a leg ulcer, 11 of those were surinfected. Half the ulcers dated back over 6 months. The would preparation included a careful cleaning with a permanganate or dakin's solution. In most of the cases, the product was applied on a once a day basis during an average period of 30 days. In 12 patients, the severity of the infection needed an additional antibiotherapy administered orally. The results were expressed in relation to the activity on the infection and wound healing. In 28 patients, the signs of infection disappeared completely. The wound healing effect was very satisfying in 22 patients (19 of them had varicose or post-phlebitis ulcers). The value of the results is independent on the date of onset and on the area of the lesions. The tolerance was good; only 4 patients suffered from itching after the application of the compound. It is mainly through his wound healing effect that Pulvo 47 Neomycine represents a progress compared to other similar specialties.
mesh_terms: D000328:Adult; D000336:Aerosols; D000368:Aged; D002374:Catalase / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007785:Lactose / Q000008:administration & dosage; D007871:Leg Ulcer / Q000188:drug therapy*; D008274:Magnesium / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009355:Neomycin / Q000008:administration & dosage*; D013228:Stearates / Q000008:administration & dosage; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D000336:Aerosols; D004338:Drug Combinations; D013228:Stearates; D002374:Catalase; D009355:Neomycin; D008274:Magnesium; D007785:Lactose
vernacular_title: Essai clinique de Pulvo 47 Néomycine dans le traitement des ulcères de jambes.