The effects of 2-thiophenecarboxylic acid on serum ionic calcium and magnesium levels in rats.
1. Administration of 2-thiophenecarboxylic acid to rats maintained on a low calcium diet resulted in a significant depression in the serum levels of total and ionized calcium and inorganic phosphate. 2. The serum magnesium levels were not altered by the drug.
D000818:Animals; D002118:Calcium / Q000097:blood*; D002264:Carboxylic Acids / Q000494:pharmacology; D003864:Depression, Chemical; D006863:Hydrogen-Ion Concentration; D008274:Magnesium / Q000097:blood*; D008297:Male; D010710:Phosphates / Q000097:blood; D051381:Rats; D013876:Thiophenes / Q000494:pharmacology*
D002264:Carboxylic Acids; D010710:Phosphates; D013876:Thiophenes; D008274:Magnesium; D002118:Calcium