title: Cyclic nucleotide phosphodiesterase in silkworm. Developmental change of cyclic AMP and cyclic GMP phosphodiesterases.
abstract: Changes in theactivities of two cyclic AMP phosphodiesterases (II and III, EC 3.1.4.17) and cyclic GMP phosphodiesterase during development were studied in silkworm, Bombyx mori. The developmental patterns of the activities of the two cyclic AMP phosphodiesterases were similar to each other, but they differed distinctly from that of cyclic GMP phosphodiesterase. The ratios of cyclic GMP phosphodiesterase/cyclic AMP phosphodiesterase III were constant in larva, but changed greatly and rapidly before pupation.
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000378:metabolism; D000818:Animals; D012831:Bombyx / Q000201:enzymology* / Q000254:growth & development; D006152:Cyclic GMP; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008274:Magnesium / Q000494:pharmacology; D008345:Manganese / Q000494:pharmacology; D008675:Metamorphosis, Biological; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism*
chemical_list: D008345:Manganese; D010727:Phosphoric Diester Hydrolases; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D006152:Cyclic GMP; D008274:Magnesium