Restoration by levamisole of rosette-forming cells inhibited by histamine, db-CAMP and adenosine.
Db-cAMP and adenosine in vitro markedly inhibited the E-rosette formation of peripheral T-cells of healthy subjects. Histamine in vitro also inhibited the E-rosette formation, but only in patients with allergic disorders. Levamisole in vitro significantly restored the E-rosette formation of T-cells inhibited by db-cAMP, adenosine and histamine.
D000241:Adenosine / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D003994:Bucladesine / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D006632:Histamine / Q000494:pharmacology*; D006633:Histamine Antagonists; D006801:Humans; D066298:In Vitro Techniques; D007978:Levamisole / Q000494:pharmacology*; D012397:Rosette Formation
D006633:Histamine Antagonists; D007978:Levamisole; D003994:Bucladesine; D006632:Histamine; D000241:Adenosine