At least three human neutrophil lysosomal proteases are capable of degrading joint connective tissues.
D001172:Arthritis, Rheumatoid / Q000201:enzymology; D002403:Cathepsins / Q000378:metabolism; D003094:Collagen / Q000378:metabolism; D003238:Connective Tissue / Q000378:metabolism*; D004549:Elastin / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism*; D006098:Granulocytes / Q000201:enzymology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007596:Joints / Q000378:metabolism*; D007704:Kininogens / Q000378:metabolism; D008247:Lysosomes / Q000201:enzymology*; D003012:Microbial Collagenase / Q000378:metabolism; D009504:Neutrophils / Q000201:enzymology*; D010196:Pancreatic Elastase / Q000378:metabolism; D011509:Proteoglycans / Q000378:metabolism
D007704:Kininogens; D011509:Proteoglycans; D003094:Collagen; D004549:Elastin; D002403:Cathepsins; D010450:Endopeptidases; D010196:Pancreatic Elastase; D003012:Microbial Collagenase