Selective inhibitors of Ca2+-binding modulator of phosphodiesterase produce vascular relaxation and inhibit actin-myosin interaction.
D015106:3',5'-Cyclic-GMP Phosphodiesterases / Q000037:antagonists & inhibitors; D000199:Actins / Q000378:metabolism*; D000205:Actomyosin / Q000378:metabolism; D000818:Animals; D001013:Aorta, Thoracic / Q000187:drug effects; D002118:Calcium / Q000378:metabolism*; D002352:Carrier Proteins / Q000037:antagonists & inhibitors*; D002417:Cattle; D004789:Enzyme Activation; D005260:Female; D066298:In Vitro Techniques; D008297:Male; D009218:Myosins / Q000378:metabolism*; D010726:Phosphodiesterase Inhibitors / Q000494:pharmacology*; D011485:Protein Binding / Q000187:drug effects; D011817:Rabbits; D014664:Vasodilation / Q000187:drug effects*
D000199:Actins; D002352:Carrier Proteins; D010726:Phosphodiesterase Inhibitors; D000205:Actomyosin; D015106:3',5'-Cyclic-GMP Phosphodiesterases; D009218:Myosins; D002118:Calcium