Interferon production by rabies strains isolated from wild rodents.
Eight rabies strains isolated from wild rodents produced interferon in laboratory mouse brains the second day after inoculation. Low levels of interferon were also detected in the serum, kidneys and lungs of the animals. The dosage and route of inoculation had no pronounced effect on interferon production.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001681:Biological Assay; D001921:Brain / Q000378:metabolism; D003604:Czechoslovakia; D007372:Interferons / Q000032:analysis / Q000096:biosynthesis*; D007668:Kidney / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D051379:Mice; D009500:Neutralization Tests; D011818:Rabies / Q000378:metabolism; D011820:Rabies virus / Q000254:growth & development* / Q000276:immunology / Q000302:isolation & purification; D012377:Rodentia / Q000382:microbiology*
D000914:Antibodies, Viral; D007372:Interferons