Responses of the early chick embryo to external cAMP sources.
Early chick embryos were stimulated with local sources of cAMP. Three major effects were observed: bending of the embryonic axis, attraction of cells on the ventral surface of the embryo, and disruption of the blastodisc. Each had a characteristic concentration dependence. These results are compared with those from studies of cells disaggregated from similar embryos.
D000818:Animals; D002642:Chick Embryo / Q000166:cytology / Q000187:drug effects*; D000242:Cyclic AMP / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005775:Gastrula / Q000187:drug effects; D007700:Kinetics; D013268:Stimulation, Chemical
D000242:Cyclic AMP