title: Maintenance of Fc receptors in hybrid cell lines obtained by fusing mouse splenic macrophages with mouse myeloma cells.
abstract: Mouse splenic macrophages were fused with cells of the mouse myeloma line P3-X63-Ag8 in the presence of inactivated Sendai virus. Two continuously growing hybrid cell lines were established from fusion mixtures. These hybrid cell lines exhibited macrophage-like morphology and continued to express macrophage derived Fc receptor activity even after prolonged culture in vitro.
mesh_terms: D000818:Animals; D002460:Cell Line; D006822:Hybrid Cells / Q000276:immunology*; D007141:Immunoglobulin Fc Fragments; D008264:Macrophages / Q000276:immunology*; D051379:Mice; D009101:Multiple Myeloma; D010222:Parainfluenza Virus 1, Human; D011971:Receptors, Immunologic / Q000378:metabolism*; D013154:Spleen
chemical_list: D007141:Immunoglobulin Fc Fragments; D011971:Receptors, Immunologic