title: Effects of lead nitrate on the activities of a few enzymes in the kidney and ovary Heteropneustes fossillis.
abstract: The effect of LC(50) and a sublethal concentration of lead nitrate on the activities of alkaline phosphatase, acid phosphatase, glucose-6-phosphatase, lipase and urease in the kidneys and ovaries of a teleost fish, Channa punctatus has been examined after 96 hr and 30 days respectively. The results show that all the five enzymes in the two tissues are inhibited significantly at both the experimental stages. However, the inhibition produced after 30 days by the sublethal concentration ish higher indicating the cumulative action of lead. Further, the inhibition of enzymes is, more marked in kidney than in the ovary.
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D005260:Female; D005399:Fishes / Q000378:metabolism*; D005952:Glucose-6-Phosphatase / Q000378:metabolism; D007668:Kidney / Q000187:drug effects* / Q000201:enzymology; D007854:Lead / Q000494:pharmacology*; D007855:Lead Poisoning / Q000201:enzymology*; D008049:Lipase / Q000378:metabolism; D009566:Nitrates / Q000494:pharmacology*; D010053:Ovary / Q000187:drug effects* / Q000201:enzymology; D014510:Urease / Q000378:metabolism
chemical_list: D009566:Nitrates; D007854:Lead; D008049:Lipase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D005952:Glucose-6-Phosphatase; D014510:Urease