[Effect of linoleic acid and products of its free radical oxidation on succinate dehydrogenase].
Effects of linoleic acid and its oxidation products (with 75--80% content of hydroperoxide) on isolated succinate dehydrogenase were studied by means of spectrophotometry and ESR-spectroscopy. It was shown that unlike the unoxidized acid, low concentrations of its oxidation products increased catalytic activity, while its high concentrations of its oxidation products increased catalytic activity, while its high concentrations brought about a decrease of SH-group content and the amplitude of ESR signal of reduced nonheme iron in the enzyme.
D001665:Binding Sites; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D008041:Linoleic Acids; D010084:Oxidation-Reduction; D011487:Protein Conformation; D013385:Succinate Dehydrogenase
D005609:Free Radicals; D008041:Linoleic Acids; D013385:Succinate Dehydrogenase
Vliianie linolevoĭ kisloty i produktov ee svobodnoradikal'no okisleniia na suktsinatdegidrogenazu.