title: Simultaneous pharmacokinetics of alclofenace in plasma and synovial fluid in patients with rheumatoid arthritis.
abstract: The simultaneous pharmacokinetics of alclofenac in the plasma and synovial fluid of 10 patients with rheumatoid arthritis were studied after a single 1 g. oral dose. A gas-liquid chromatographic method was used for assaying alclofenac in both plasma and synovial fluid. Alclofenac readily appears in the plasma and synovial fluid.
mesh_terms: D000284:Administration, Oral; D001172:Arthritis, Rheumatoid / Q000378:metabolism*; D006801:Humans; D010648:Phenylacetates / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D013582:Synovial Fluid / Q000378:metabolism*
chemical_list: D010648:Phenylacetates