Reconstruction of rat skeletal muscle glycerophosphate shuttle.
The activity of alpha-glycerophosphate shuttle in homogenate and in a reconstructed system (isolated mitochondria and cytoplasm) from rat skeletal muscle is presented. The influence of some inhibitors of mitochondrial alpha-glycerosphate dehydrogenase on the activity alpha-glycerophosphate shuttle is demonstrated. The possible operativity of alpha-glycerophosphate shuttle in skeletal muscle in vivo is discussed.
D000818:Animals; D002474:Cell-Free System; D003593:Cytoplasm / Q000378:metabolism; D005993:Glycerolphosphate Dehydrogenase / Q000378:metabolism; D005994:Glycerophosphates / Q000378:metabolism*; D008931:Mitochondria, Muscle / Q000378:metabolism*; D009132:Muscles / Q000378:metabolism*; D009243:NAD / Q000378:metabolism; D010101:Oxygen Consumption; D051381:Rats
D005994:Glycerophosphates; D009243:NAD; D005993:Glycerolphosphate Dehydrogenase