title: In vitro system for studying the efficacy of antiviral agents in preventing the reactivation of latent herpes simplex virus.
abstract: Antiviral antibody and interferon did not prevent in vitro reactivation of herpes simplex virus in latently infected sensory ganglia. Phosphonoacetic acid and 9-beta-d-arabinofuranosyladenine blocked reactivation, but this treatment did not eradicate the latent infection.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral; D000998:Antiviral Agents / Q000494:pharmacology*; D005260:Female; D005724:Ganglia / Q000382:microbiology; D006561:Herpes Simplex / Q000276:immunology / Q000382:microbiology; D007372:Interferons / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C; D010746:Phosphonoacetic Acid / Q000494:pharmacology; D018139:Simplexvirus / Q000187:drug effects*; D014740:Vidarabine / Q000494:pharmacology
chemical_list: D000914:Antibodies, Viral; D000998:Antiviral Agents; D007372:Interferons; D014740:Vidarabine; D010746:Phosphonoacetic Acid