Rapid purification of lymphocytic choriomeningitis virus by density gradient centrifugation in colloidal silica.
Lymphocytic choriomeningitis virus was purified from cell culture fluid by density gradient centrifugation in colloidal silica. The specific infectivity increased 5000-fold and the recovery of infectivity was about 10%.
D002460:Cell Line; D002499:Centrifugation, Density Gradient; D003102:Colloids; D008217:Lymphocytic choriomeningitis virus / Q000254:growth & development / Q000302:isolation & purification*; D008722:Methods; D012822:Silicon Dioxide
D003102:Colloids; D012822:Silicon Dioxide