In vivo effect of endrin on three phosphatases in kidney and liver of the fish Ophiocephalus punctatus.
The effect of endrin (0.030 ppm) on the acid phosphatase, alkaline phosphatase and glucose-6-phosphatase activities in the kidney and liver of a teleost fish, Ophiocephalus (Channa) punctatus has been studied. The period of exposure was twenty days. An increase in the acid phosphatase activity is noted in the two tissues examined here. There is no significant change in the activity of alkaline phosphatase in kidney while in liver the enzyme is inhibited. In the kidney glucose-6-phosphatase showed a slight increase in activity but it is inhibited in liver.
D000135:Acid Phosphatase / Q000037:antagonists & inhibitors; D000469:Alkaline Phosphatase / Q000037:antagonists & inhibitors; D000818:Animals; D004732:Endrin / Q000494:pharmacology*; D005399:Fishes / Q000378:metabolism*; D005952:Glucose-6-Phosphatase / Q000037:antagonists & inhibitors; D007668:Kidney / Q000187:drug effects / Q000201:enzymology*; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D010744:Phosphoric Monoester Hydrolases / Q000037:antagonists & inhibitors*
D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D010744:Phosphoric Monoester Hydrolases; D005952:Glucose-6-Phosphatase; D004732:Endrin