Computerized double-tracer subtraction scanning with gallium-67 citrate in inflammatory diseases.
A gallium-67/technetium-99m subtraction technique was used with a variable weighting factor. That is, each image was separately set to 100%. Varying amounts of the Tc-99m images were subtracted from those of Ga-67. A total of 95 patients who had radiogallium scanning for suspected inflammatory disease were studied by the subtraction technique. Thirty of these patients had abnormal Tc-99m pyrophosphate bone scans, while 20 had abnormal radiogallium abdominal foci; 45 had defects in liver, spleen, or kidney images. The subtraction technique with variable weighting was highly successful in enhancing hot-spot visibility, and in providing information as to the anatomic location of the defect.
D000038:Abscess / Q000000981:diagnostic imaging; D000328:Adult; D001170:Arthritis, Infectious / Q000000981:diagnostic imaging; D002951:Citrates; D003201:Computers; D011756:Diphosphates; D005260:Female; D005710:Gallium Radioisotopes; D006801:Humans; D007249:Inflammation / Q000000981:diagnostic imaging*; D007674:Kidney Diseases / Q000000981:diagnostic imaging; D008100:Liver Abscess / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging / Q000379:methods*; D013158:Splenic Diseases / Q000000981:diagnostic imaging; D013667:Technetium
D002951:Citrates; D011756:Diphosphates; D005710:Gallium Radioisotopes; D013667:Technetium