title: [Influence of a hypertonic medium on cell susceptibility to foot-and-mouth disease virus].
abstract: The influence of hypertonic medium on the relationship between two cell clones of IB-RS-2 swine line and the foot-and-mouth disease virus was studied. Although the number of infected cells was increased by the cell treatment with the hypertonic medium, before or during the time of virus adsorption and penetration onto the cells, showed by the plaque number, the viral replication was partially inhibited as showed by the plaque size as by the viral yield in one-cycle of infection. On the other hand, the cell treatment with that medium after virus adsorption and penetration time inhibited as the plaque number and size as the yield of the foot-and-mouth disease virus.
mesh_terms: D000818:Animals; D005537:Aphthovirus / Q000254:growth & development* / Q000276:immunology; D002460:Cell Line; D002478:Cells, Cultured / Q000187:drug effects; D003470:Culture Media; D006131:Growth Inhibitors / Q000494:pharmacology; D006982:Hypertonic Solutions / Q000494:pharmacology*; D066298:In Vitro Techniques; D007668:Kidney; D013552:Swine; D010948:Viral Plaque Assay; D014779:Virus Replication / Q000187:drug effects
chemical_list: D003470:Culture Media; D006131:Growth Inhibitors; D006982:Hypertonic Solutions
vernacular_title: Influência de meio hipertônico sobre a susceptibilidade celular ao vírus da febre aftosa.