title: Study of cell surface antigens induced by herpes simplex virus. Note II. Some properties of the antigens.
abstract: Surface antigens induced by herpes simplex virus infection in HeLa cells remain unaltered after treatment of the cells with 2% formalin for 10 min or with 0.08% trypsin for 15 min at 37 degrees C. A longer trypsin treatment (for 1 hour) will cause gradual alterations in the virus-induced antigens. Hence, these antigens are proteins deeply implanted within the cellular membrane. Their mobility--optimal at 37 degrees C--allows aggregation of the antigens in the form of caps or patches by polyvalent ligands such as IgG.
mesh_terms: D000954:Antigens, Surface / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis*; D005557:Formaldehyde / Q000494:pharmacology; D006367:HeLa Cells; D018139:Simplexvirus / Q000276:immunology*; D013210:Staphylococcus; D014357:Trypsin / Q000494:pharmacology; D014776:Virus Cultivation
chemical_list: D000954:Antigens, Surface; D000956:Antigens, Viral; D005557:Formaldehyde; D014357:Trypsin