title: Primary hepatocellular carcinoma in Australia: Aetiological considerations.
abstract: This is a study of aetiological associations in patients with primary hepatocellular carcinoma (PHC). Thirty new patients with PHC were seen in a five-year period. The most common aetiological association was alcoholic cirrhosis. This was implicated in the development of PHC in 13 patients. However, since the introduction of radioimmunoassay for hepatitis B surface antigen (HBsAg) there have been six patients with HBsAg-associated PHC. Thus, for the first time, an association of hepatitis B virus with PHC is described in this country.
mesh_terms: D001315:Australia; D006528:Carcinoma, Hepatocellular / Q000209:etiology* / Q000276:immunology; D005260:Female; D006509:Hepatitis B / Q000150:complications*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications* / Q000276:immunology; D008113:Liver Neoplasms / Q000209:etiology* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay
chemical_list: D006514:Hepatitis B Surface Antigens