title: An appraisal of the relationship between primary hepatocellular carcinoma and hepatitis B virus.
abstract: The association between hepatitis B virus infection and primary hepatocellular carcinoma is reviewed. On the basis of serological and tissue examination there is a close link between virus infection and the tumour. While there is evidence to favour an oncogenic role for virus this is not conclusive, and other possible explanations for the relationship are discussed.
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006115:Greece; D006509:Hepatitis B / Q000150:complications* / Q000453:epidemiology; D006511:Hepatitis B Antigens / Q000032:analysis; D006801:Humans; D066298:In Vitro Techniques; D008103:Liver Cirrhosis / Q000150:complications; D008113:Liver Neoplasms / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D014481:United States
chemical_list: D006511:Hepatitis B Antigens