Leydig cell hypoplasia: a cause of male pseudohermaphroditism.
A patient with male pseudohermaphroditism is presented whose testicular biopsy showed marked paucity of the Leydig cell populations to which is attributed testosterone deficiency and impaired spermatogenesis.
D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000728:Androgens / Q000097:blood; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D012734:Disorders of Sex Development / Q000209:etiology*; D004967:Estrogens / Q000097:blood; D006801:Humans; D007985:Leydig Cells / Q000473:pathology*; D008297:Male; D013091:Spermatogenesis; D013733:Testicular Diseases / Q000150:complications*; D013737:Testis / Q000166:cytology; D013739:Testosterone / Q000097:blood / Q000172:deficiency
D000728:Androgens; D006063:Chorionic Gonadotropin; D004967:Estrogens; D013739:Testosterone; D000324:Adrenocorticotropic Hormone