title: Synaptic function in the nervous system: a theory and its application.
abstract: The objective of this paper is to present a new theory of synaptic function in the nervous system. The basis for this theory is the experimental demonstration that a nerve impulse assumes five different forms as it advances through the synaptic region, and that five basic mathematical operations have been identified as being involved in the transformation of one form into another form. As a result of these data, the synaptic region is regarded as a functional unit where information coming to it is unpacked, processed, stored, and retrieved for transit to another synaptic region or effector site. The data also suggests that a nerve impulse is a bolus of energy, therefore, without substance; that it contains information coded in its shape or form; that it is precisely described mathematically. Furthermore, the data suggests synaptic regions process these nerve impulses by applying mathematical operations to them; that function in the synaptic region is highly stereotyped (programmed); that chemical substances are associated with the mathematical operations. The basic approach of this theory is to regard a significant portion of the nervous system as an 'interface' between the external universe and man himself. As an interface, the nervous system receives and processes information from both the external universe and man himself in a programmed manner. The interface functions by converting the information it receives into a bolus of energy, the nerve impulse, then processes the bolus by converting it into numbers or functions and applying mathematical operation to it.
mesh_terms: D000109:Acetylcholine / Q000502:physiology*; D000110:Acetylcholinesterase / Q000502:physiology*; D000200:Action Potentials; D000818:Animals; D005728:Ganglia, Sympathetic / Q000502:physiology* / Q000503:physiopathology; D011558:Herpesvirus 1, Suid; D008959:Models, Neurological; D009433:Neural Inhibition; D011557:Pseudorabies / Q000503:physiopathology*; D051381:Rats; D013569:Synapses / Q000502:physiology*; D013570:Synaptic Membranes / Q000502:physiology; D009435:Synaptic Transmission
chemical_list: D000110:Acetylcholinesterase; D000109:Acetylcholine