title: Association of lysolecithin acyltransferase with the high density lipoproteins and its activation by the low density lipoproteins in normal human plasma.
abstract: The lysolecithin acyltransferase of human plasma is shown to be associated with the high-density lipoprotein fraction. Although the low density lipoproteins do not have intrinsic enzyme activity, their presence activated the enzyme 3--7-fold. This activation is not affected by heat-treatment of the low density lipoproteins, but is abolished by the addition of heparin.
mesh_terms: D008243:1-Acylglycerophosphocholine O-Acyltransferase / Q000097:blood*; D000217:Acyltransferases / Q000097:blood*; D000328:Adult; D004789:Enzyme Activation / Q000187:drug effects; D006493:Heparin / Q000494:pharmacology; D006358:Hot Temperature; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood*; D008297:Male
chemical_list: D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D006493:Heparin; D000217:Acyltransferases; D008243:1-Acylglycerophosphocholine O-Acyltransferase