Appearance of immunoglobulin G Fc receptor in cultured human cells infected with varicella-zoster virus.
After infection with varicella-zoster virus, HeLa and human embryo lung cells developed a receptor for the Fc portion of human and rabbit immunoglobulin G. The receptor was detected by both hemadsorption and immunofluorescence, using antibody-coated erythrocytes and heat-aggregated immunoglobulin G. However, sheep erythrocytes sensitized with F(ab')2 of anti-sheep erythrocyte antibody did not adsorb to the receptor. When cell-free varicella-zoster virus was inoculated into the HeLa cell monolayer, the Fc receptor appeared at first 6 h after infection; varicella-zoster virus antigen in the cytoplasm and detectable cytopathic effects appeared later.
D000818:Animals; D002460:Cell Line; D004622:Embryo, Mammalian; D004912:Erythrocytes / Q000276:immunology; D005455:Fluorescent Antibody Technique; D006367:HeLa Cells; D006382:Hemadsorption; D014645:Herpesvirus 3, Human / Q000276:immunology*; D006801:Humans; D008168:Lung; D011961:Receptors, Fc / Q000096:biosynthesis* / Q000276:immunology; D012756:Sheep / Q000276:immunology; D014779:Virus Replication
D011961:Receptors, Fc