title: Tumor cell interactions in vitro microtubules, 100 angstrom filaments, and contractile microfilaments of tumor cells involved in "emperipolesis".
abstract: An increase in the number of examples of emperiopolesis, i.e., cells within cells, was observed subsequently to addition of Bt2cAMP to spinner flask cultures of JB-1-E tumor cells. A conspicuous arrangement of microtubules and 100 angstrom filaments in the tumor cells involved in emperiopelesis was observed. Absence of emperipolesis in cultures treated with cytochalasin B indecates a possible role of the contractile microfilaments in the events leading to emperiopolesis. The significance of and the term emperipolesis are discussed.
mesh_terms: D000818:Animals; D003994:Bucladesine / Q000494:pharmacology*; D002460:Cell Line; D002478:Cells, Cultured; D003571:Cytochalasin B / Q000494:pharmacology*; D003599:Cytoskeleton; D051379:Mice; D008806:Mice, Inbred AKR; D008870:Microtubules; D010954:Plasmacytoma / Q000648:ultrastructure*
chemical_list: D003571:Cytochalasin B; D003994:Bucladesine