title: Comparative analysis of GS and BK virus genomes.
abstract: Analysis of heteroduplexing between the genomes of GS virus, a BK-group virus, and the prototype BK virus revealed one region of nonhomology. Further analysis by cleavage of viral DNA with the restriction endonucleases EcoRI, HindIII, and HaeIII revealed that base changes in the GS virus genome spanned 0.6 to 0.7 map unit from the EcoRI site. Large T and small t antigens of GS virus appear to be similar in size to the BK virus antigens.
mesh_terms: D000951:Antigens, Neoplasm / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D001739:BK Virus / Q000032:analysis* / Q000235:genetics; D001483:Base Sequence; D002460:Cell Line; D004262:DNA Restriction Enzymes / Q000378:metabolism; D004279:DNA, Viral / Q000032:analysis*; D005814:Genes, Viral; D006801:Humans; D007668:Kidney / Q000196:embryology; D009690:Nucleic Acid Conformation; D009692:Nucleic Acid Heteroduplexes / Q000032:analysis; D011120:Polyomavirus / Q000032:analysis* / Q000235:genetics / Q000276:immunology
chemical_list: D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D004279:DNA, Viral; D009692:Nucleic Acid Heteroduplexes; D004262:DNA Restriction Enzymes