title: The lipopolysaccharides of Neisseria gonorrhoeae colony types 1 and 4.
abstract: The lipopolysaccharides (LPS) of strains of Neisseria gonorrhoeae grown in type 1 (T1) and 4 (T4) colony forms have been isolated. LPS from T4 colony type cells on mild hydrolysis gave a lipid A and a core oligosaccharide composed of 2-amino-2-deoxy-D-glucose, D-glucose, D-galactose, L-glycero-D-manno-heptose and 3-deoxy-D-manno-octuosonic acid that appeared to be common to all the strains examined. LPS from T1 colony type cells on mild hydrolysis gave a lipid A and high molecular weight O polysacc,arides which showed considerable differences in glycose composition for each strain examined. In those strains examined, T4 cells appear to produce a common "R" type LPS whereas T1 cells produce an "S" type LPS with structurally different O polysaccharide structures which probably account for serologically differentiated strains of N. gonorrhoeae.
mesh_terms: D000606:Amino Sugars / Q000032:analysis; D000942:Antigens, Bacterial / Q000032:analysis*; D001426:Bacterial Proteins / Q000032:analysis; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D008070:Lipopolysaccharides / Q000032:analysis / Q000302:isolation & purification / Q000378:metabolism*; D009005:Monosaccharides / Q000032:analysis; D009344:Neisseria gonorrhoeae / Q000254:growth & development / Q000378:metabolism*; D010758:Phosphorus / Q000032:analysis; D011135:Polysaccharides, Bacterial / Q000032:analysis; D013045:Species Specificity; D013400:Sugar Acids / Q000032:analysis
chemical_list: D000606:Amino Sugars; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D008070:Lipopolysaccharides; D009005:Monosaccharides; D011135:Polysaccharides, Bacterial; D013400:Sugar Acids; D010758:Phosphorus