Construction of hybrid viruses in vitro and their possible use for the production of specific viral or cellular proteins.
The use of plasmid and bacteriophage vectors for cloning of DNA segments from procaryotes and eucaryotes is described. A similar approach is being developed with DNA viruses like simian virus 40 or adenovirus 2. Such hybrid viruses may permit the amplification of specific genes and the overproduction of the corresponding proteins.
D000260:Adenoviruses, Human / Q000235:genetics*; D001419:Bacteria / Q000235:genetics; D001435:Bacteriophages; D004274:DNA, Recombinant; D004279:DNA, Viral / Q000235:genetics; D005814:Genes, Viral; D006824:Hybridization, Genetic; D010957:Plasmids; D013539:Simian virus 40 / Q000235:genetics*; D014161:Transduction, Genetic; D014764:Viral Proteins / Q000235:genetics*
D004274:DNA, Recombinant; D004279:DNA, Viral; D014764:Viral Proteins