title: Kinetic control of phosphoglycerate mutase from Flavobacterium sp. grown on ethylene glycol.
abstract: A species of Flavobacterium able to oxidise ethylene glycol to pyruvate via glyoxylate, glycerate, 2-phosphoglycerate and phosphoenolpyruvate exploits phosphoglycerate mutase to initiate gluconeogenesis. Partially purified phosphoglycerate mutase from this bacterium is independent of adenylate charge control but is activated by phosphoenolpyruvate. The possible significance of this regulation is discussed.
mesh_terms: D000105:Acetyl Coenzyme A / Q000494:pharmacology; D002951:Citrates / Q000494:pharmacology; D005026:Ethylene Glycols / Q000378:metabolism*; D005417:Flavobacterium / Q000201:enzymology*; D007700:Kinetics; D009711:Nucleotides / Q000494:pharmacology; D010728:Phosphoenolpyruvate / Q000494:pharmacology; D010736:Phosphoglycerate Mutase / Q000378:metabolism*; D010770:Phosphotransferases / Q000378:metabolism*
chemical_list: D002951:Citrates; D005026:Ethylene Glycols; D009711:Nucleotides; D000105:Acetyl Coenzyme A; D010728:Phosphoenolpyruvate; D010770:Phosphotransferases; D010736:Phosphoglycerate Mutase