High-affinity binding processes for GABA, glycine, and beta-alanine in synaptosome-enriched fractions of rats CNS.
A bicuculline-sensitive component of the binding of GABA and strychnine-sensitive components of the binding of glycine and beta alanine to synaptosome-enriched fractions of rat CNS have been demonstrated in the presence of physiological concentrations of Na+ and other inorganic ions. These processes might be related to synaptic receptors for these inhibitory amino-acids.
D000409:Alanine / Q000378:metabolism*; D000818:Animals; D002490:Central Nervous System / Q000378:metabolism*; D005998:Glycine / Q000378:metabolism*; D066298:In Vitro Techniques; D051381:Rats; D017981:Receptors, Neurotransmitter / Q000378:metabolism; D013574:Synaptosomes / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D017981:Receptors, Neurotransmitter; D005680:gamma-Aminobutyric Acid; D000409:Alanine; D005998:Glycine