Tumor promoter 12-O-tetradecanoylphorbol-13-acetate is not a prostaglandin E-type agonist.
The tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA), proposed to fit a prostaglandin type receptor, does not compete with [3H] prostaglandin E1 (PGE1) for the established PGE1 receptor of fat cells.
D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D001667:Binding, Competitive; D066298:In Vitro Techniques; D008297:Male; D010704:Phorbols / Q000494:pharmacology*; D011459:Prostaglandins E, Synthetic / Q000378:metabolism*; D051381:Rats; D011956:Receptors, Cell Surface / Q000187:drug effects*; D011982:Receptors, Prostaglandin / Q000187:drug effects* / Q000378:metabolism; D013755:Tetradecanoylphorbol Acetate / Q000378:metabolism / Q000494:pharmacology*
D010704:Phorbols; D011459:Prostaglandins E, Synthetic; D011956:Receptors, Cell Surface; D011982:Receptors, Prostaglandin; D013755:Tetradecanoylphorbol Acetate