title: [Treatment of duodenal ulcers with antacid mixtures and sulpiride. A double-blind controlled study (author's transl)].
abstract: A total of 108 patients with duodenal ulcers were divided into 4 groups in a double-blind study controlled by endoscopic examinations. Patients in each group were given either an antacid mixture or sulpiride alone, antacid mixture plus sulpiride, or a placebo. The highest complete recovery rate (84 per cent) was noted in the antacid mixture plus sulpiride group, while partial healing (more than 50 per cent reduction in ulcer size) was highest in the sulpiride group (84,6 per cent). As sulpiride has both healing effects on the ulcer and an analgesic effect against pain it can be prescribed in association with antacid mixtures for the treatment of duodenal ulcers.
mesh_terms: D000863:Antacids / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D013469:Sulpiride / Q000627:therapeutic use*
chemical_list: D000863:Antacids; D013469:Sulpiride
vernacular_title: Traitement de l'ulcère duodénal par les pansements digestifs et le sulpiride: étude en double aveugle.