title: The effect of controlled halothane anaesthesia on splanchnic oxygen consumption in the dog.
abstract: The influence of halothane ansesthesia on splanchnic oxygen flow and oxygen uptake was studied in seven dogs. Mean oxygen supply to the liver and the portally-drained tissues decreased significantly to 44% and 53% of control values, respectively, while mena oxygen consumption diminished insignificantly to 68% and 82% of control values, respectively. There was a fall in the oxygen flow/oxygen consumption ratio in all animals following halothane. The relatively unimpaired oxygen uptake, in spite of a diminished oxygen supply, led to an increased extraction of oxygen by the tissues. Some factors affecting oxygen utilisation during halothane anaesthesia are discussed.
mesh_terms: D000005:Abdomen; D000758:Anesthesia; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D001831:Body Temperature; D002245:Carbon Dioxide / Q000097:blood; D004285:Dogs; D006221:Halothane / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D008099:Liver / Q000378:metabolism; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption / Q000187:drug effects*; D010313:Partial Pressure; D012039:Regional Blood Flow / Q000187:drug effects; D012119:Respiration
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen; D006221:Halothane