Streptozotocin: an inactive agent in small cell carcinoma.
Fifteen patients with advanced small cell carcinoma of the lung were treated with streptozotocin. No objective reponses were seen. A review of the literature reveals no objective response in a total of 56 patients, indicating that this agent is inactive as a single agent in small cell carcinoma.
D018288:Carcinoma, Small Cell / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D013311:Streptozocin / Q000009:adverse effects / Q000627:therapeutic use*; D014839:Vomiting / Q000139:chemically induced
D013311:Streptozocin