[Histochemical characteristics of the mucus in pseudomyxoma peritonei].
Histochemical investigations of gelatinous masses of 3 patients with pseudomyxoma peritonei were carried out. The tissues of the mucinous adenocarcinoma of the ovary and normal appendix were used for comparison. The results showed that the mucus in pseudomyxoma peritonei as well as that of the epithelial cells of the appendix belonged to the group of acid nonsulfurated mucoid substances of epithelial origin rich in syalic acid. The mucus in the mucinous adenocarcinoma of the ovary had the same histochemical properties, except for its resistance to neuraminidase. Some suggestions on the pathogenetic mechanisms of the development of the disease and possibilities of therapeutic applications of neuraminidase are presented.
D002288:Adenocarcinoma, Mucinous / Q000378:metabolism; D000328:Adult; D001065:Appendix / Q000378:metabolism; D003537:Cystadenoma / Q000378:metabolism*; D004848:Epithelium / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009093:Mucus / Q000378:metabolism*; D010051:Ovarian Neoplasms / Q000378:metabolism; D010534:Peritoneal Neoplasms / Q000378:metabolism*
Gistokhimicheskaia kharakteristika slizi pri psevdomiksome briushiny.