Non-specific decrease of cell-mediated immunity in female mice during syngeneic and allogeneic pregnancy.
Cell-mediated immunity is non-specifically reduced in the second half of H-2 incompatible pregnancy compared with syngeneic mating. Significant difference between syngeneic and allogeneic mated female mice was obtained using two independent tests: contact sensitivity to oxazolone (P smaller than 0.001) and local graft-versus-host reaction (P smaller than 0.01).
D000818:Animals; D005260:Female; D006087:Graft vs Host Reaction; D006649:Histocompatibility Antigens; D007108:Immune Tolerance; D007111:Immunity, Cellular; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011247:Pregnancy; D011270:Pregnancy, Animal
D006649:Histocompatibility Antigens