Inhibition of heart and brain cyclic adenosine 3',5'-monophosphate phosphodiesterase by new non-steroidic compounds structurally related to natural cardenolides.
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology*; D002298:Cardenolides / Q000494:pharmacology*; D002417:Cattle; D006321:Heart / Q000187:drug effects; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D009206:Myocardium / Q000201:enzymology*; D011485:Protein Binding / Q000187:drug effects; D051381:Rats
D002298:Cardenolides; D015105:3',5'-Cyclic-AMP Phosphodiesterases