[Characteristics of the combined action of fentanyl and sodium oxybutyrate on respiration].
Experiments conducted with rabbits (86) and albino rats (28) demonstrated that with the use of sodium oxybutyrate (200 mg/kg) in combination with phentanyl (0,02 mg/kg) the former reduces the depressing influence of the latter on the external respiration and tissue processes.
D000136:Acid-Base Equilibrium / Q000187:drug effects; D000472:Alkalosis, Respiratory / Q000139:chemically induced; D000818:Animals; D001769:Blood / Q000187:drug effects; D004338:Drug Combinations; D005283:Fentanyl / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D006885:Hydroxybutyrates / Q000494:pharmacology*; D008297:Male; D010101:Oxygen Consumption / Q000187:drug effects; D010313:Partial Pressure; D011188:Potassium / Q000097:blood; D011817:Rabbits; D051381:Rats; D012119:Respiration / Q000187:drug effects*; D012964:Sodium / Q000097:blood; D012978:Sodium Oxybate / Q000494:pharmacology*; D013997:Time Factors
D004338:Drug Combinations; D006885:Hydroxybutyrates; D012978:Sodium Oxybate; D012964:Sodium; D011188:Potassium; D005283:Fentanyl
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