Specificity of action of neuraminidase, according to its bacteriological origin.
Neuraminidase from Vibrio Cholerae selectively cleaves sialic acid from FSH, but leaves the LH sialic acid, not influencing the biological activity of the latter hormone. On the other hand, Neuraminidase from Clostridium perfringens does not possess this specific action and destroys the biological activity of LH as is suggested by Parlow's OAAD-test.
D003016:Clostridium perfringens / Q000201:enzymology; D007986:Luteinizing Hormone; D009439:Neuraminidase / Q000378:metabolism*; D013045:Species Specificity; D013379:Substrate Specificity; D014734:Vibrio cholerae / Q000201:enzymology
D007986:Luteinizing Hormone; D009439:Neuraminidase