The influence of Artobotrys odoratissimus Linn. extracts on phosphatase activity in the uterus of rats.
The effect of 50% ethanolic and benzene extracts of Artobotrys odoratissimus Linn., a potent antiestrogenic plant on uterine acid and alkaline phosphatase activity has been studied in adult rats. Both the extracts decreased the alkaline phosphatase activity in the uterus of intact and ovariectomized rats (P less than 0.001) but elevated the acid phosphatase activity (P less than 0.001). 50% ethanolic extract acts at low dose levels; however its activity decreases as the dose is increased. Benzene extract showed more consistent dose-response relationship.
D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D002369:Castration; D005260:Female; D066298:In Vitro Techniques; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D013997:Time Factors; D014599:Uterus / Q000187:drug effects / Q000201:enzymology*
D010936:Plant Extracts; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D010744:Phosphoric Monoester Hydrolases