Candida pachymeningitis with multiple cranial nerve pareses.
A 66-year-old woman complained of right-sided headache and was found to have progressive dysfunction of cranial nerves V and VIII through XII on the right side. At autopsy, there was a granulomatous pachymengitis involving the floor of the right middle and posterior cranial fossae due to Candida tropicalis infection. Inflammatory tissue compressed the clinically affected cranial nerves.
D000368:Aged; D002177:Candidiasis / Q000150:complications* / Q000473:pathology; D005154:Facial Nerve / Q000473:pathology; D005260:Female; D006801:Humans; D008581:Meningitis / Q000150:complications* / Q000473:pathology; D010243:Paralysis / Q000209:etiology / Q000473:pathology; D010523:Peripheral Nervous System Diseases / Q000209:etiology* / Q000473:pathology; D014276:Trigeminal Nerve / Q000473:pathology