Mechanisms of oral staphylococcal enterotoxin B-induced emesis in the monkey (38553).
Vomition is the most consistent response to oral SEB challenge in the monkey.  The technique of cross-circulation clearly differentiates local neural phenomenon from humoral mechanisms.  Our results support the theory that SED-induced vomition follows stimulation of local neural receptors in the gut.  The evidence indicates no significant amount of enterotoxin absorption or stimulation of vomition by any centrally acting humoral mechanism.
D000284:Administration, Oral; D000818:Animals; D002245:Carbon Dioxide / Q000097:blood; D003427:Cross Circulation; D004768:Enterotoxins / Q000494:pharmacology*; D005260:Female; D006386:Hemagglutination Tests; D006400:Hematocrit; D006863:Hydrogen-Ion Concentration; D008251:Macaca; D008297:Male; D009994:Osmolar Concentration; D013210:Staphylococcus; D014839:Vomiting / Q000209:etiology*
D004768:Enterotoxins; D002245:Carbon Dioxide