Antibody to lymphocytic choriomeningitis virus in children with congenital hydrocephalus.
Antibody to lymphocytic choriomeningitis (LCM) virus was found by the indirect immunofluorescence (IF) technique in high titres in 9 out of 28 children with congenital hydrocephalus and in moderate titres in 6 mothers of these seropositive children.  It is suggested that LCM virus or a closely related virus infecting the foetus in utero may play a role in the aetiopathogenesis of some cases of congenital hydrocephalus.
D000328:Adult; D000914:Antibodies, Viral; D000917:Antibody Formation; D001782:Blood Donors; D002648:Child; D002675:Child, Preschool; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000276:immunology* / Q000382:microbiology; D007223:Infant; D007231:Infant, Newborn; D008216:Lymphocytic Choriomeningitis / Q000150:complications; D008217:Lymphocytic choriomeningitis virus / Q000276:immunology*; D011247:Pregnancy
D000914:Antibodies, Viral