[Delayed healings of the epithelium of the cornea due to soft lenssolutions].
Six different soft lens solution have been tested to investigate their effect on the healing process of a corneal erosion, experimentally scratched in rabbit-cornea. Healing delays have been observed in every cases; also by three medicaments which are used for "dry" eyes. The latter ones should never have  a conjunctival application. Theexplanation of those  healing delays is given by the concentration properties of HEMA-lenses for disinfectants. The admixtures of soft lens solutions like buffers and liquid polymerscause and additive effect on retardment of coeneal regeneration.
D000818:Animals; D002021:Buffers; D002710:Chlorhexidine / Q000494:pharmacology; D003263:Contact Lenses, Hydrophilic; D003315:Cornea / Q000187:drug effects* / Q000503:physiopathology; D005035:Ethylmercury Compounds / Q000494:pharmacology; D005128:Eye Diseases / Q000503:physiopathology; D005260:Female; D005942:Gluconates / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D008297:Male; D009883:Ophthalmic Solutions; D011108:Polymers; D011817:Rabbits; D012038:Regeneration; D012459:Salicylates / Q000494:pharmacology; D012995:Solubility; D013997:Time Factors; D014867:Water
D002021:Buffers; D005035:Ethylmercury Compounds; D005942:Gluconates; D009883:Ophthalmic Solutions; D011108:Polymers; D012459:Salicylates; D014867:Water; D002710:Chlorhexidine
Abkeilungsverzögerungen des Hornhautepithels durch lösungen für weiche kontaktlinsen