title: Comparative investigations of some enzymatic parameters and liver scanning in the early detection of the malignant liver process.
abstract: In 30 patients with histologically verified malignant liver processes, the authors have examined the value of the serum activity of liver lactate dehydrogenase (LDH), alkaline phosphatase and gamma-glutamyltranspeptidase and in a number of patients, 5'-nucleotidase. These values were compared with the findings received from scintigraphy of the liver. Based on the results obtained, the authors have concluded that the activities of the gamma-glutamyltranspeptidase (gammaGT), 5'-nucleotidase and liver lactate dehydrogenase are more significantly increased in malignant processes of the liver than scintigraphy of the liver could register.
mesh_terms: D000410:Alanine Transaminase / Q000032:analysis; D000469:Alkaline Phosphatase / Q000097:blood / Q000378:metabolism*; D001219:Aspartate Aminotransferases / Q000032:analysis; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000201:enzymology / Q000473:pathology; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000201:enzymology* / Q000473:pathology; D008113:Liver Neoplasms; D009708:Nucleotidases / Q000097:blood / Q000378:metabolism*; D005723:gamma-Glutamyltransferase / Q000097:blood / Q000378:metabolism*
chemical_list: D007770:L-Lactate Dehydrogenase; D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D009708:Nucleotidases; D000469:Alkaline Phosphatase