title: Anatomical relationships between the ventral mesencephalic tegmentum--a 10 region and the locus coeruleus as demonstrated by anterograde and retrograde tracing techniques.
abstract: We have searched for anatomical connections between the ventral mesencephalic tegmentum (VMT), including the dopaminergic cell group A10 and the locus coeruleus (LC) region. Tritiated leucine (120--220 nl) and horseradish peroxidase delivered by electrophoresis were injected in the VMT-A10 region. We have demonstrated, on the one hand bilateral projections from the VMT-A10 region to LC, and on the other hand a possible contralateral projection from LC to VMT-A10 region. These relationships, reported for the first time may have some important functional significance.
mesh_terms: D000818:Animals; D004298:Dopamine; D006735:Horseradish Peroxidase / Q000494:pharmacology; D007553:Isotope Labeling; D007930:Leucine / Q000494:pharmacology; D008125:Locus Coeruleus / Q000033:anatomy & histology*; D008297:Male; D009434:Neural Pathways; D051381:Rats; D009435:Synaptic Transmission / Q000187:drug effects; D013681:Tegmentum Mesencephali / Q000033:anatomy & histology*
chemical_list: D006735:Horseradish Peroxidase; D007930:Leucine; D004298:Dopamine