Urinary purine levels in suicide.
A high-resolution liquid chromatographic system was utilized to analyze urine samples of twelve nonchemical suicide victims for the relative composition of ultraviolet-absorbing compounds. The analyses demonstrated a decrease in the output of uric acid, characteristic of severe depression, and an increase in the excretion of hypoxanthine. The excretion of 7-methylxanthine was found to be variable and xanthine was normal.
D000328:Adult; D000368:Aged; D002851:Chromatography, High Pressure Liquid; D003404:Creatinine / Q000652:urine; D003863:Depression / Q000652:urine; D000431:Ethanol / Q000097:blood; D005260:Female; D006029:Glycosuria; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007042:Hypoxanthines / Q000652:urine; D008297:Male; D008875:Middle Aged; D011687:Purines / Q000652:urine*; D012737:Sex Factors; D013405:Suicide; D014527:Uric Acid / Q000652:urine; D014556:Urine; D014970:Xanthines / Q000652:urine
D007042:Hypoxanthines; D011687:Purines; D014970:Xanthines; D014527:Uric Acid; D000431:Ethanol; D003404:Creatinine