Procaine in porcine malignant hyperthermia.
Serum creatine phosphokinase, rectal temperature and muscle pH at death were measured in three halothane-susceptible Landrace pigs. Two of the pigs were treated with procaine. Although the course of the syndrome was different in the treated pigs, procaine did not reverse the established malignant hyperthermia syndrome.
D000818:Animals; D001831:Body Temperature; D003402:Creatine Kinase / Q000097:blood; D006221:Halothane; D006863:Hydrogen-Ion Concentration; D007275:Injections, Intravenous; D008305:Malignant Hyperthermia / Q000139:chemically induced / Q000188:drug therapy* / Q000201:enzymology; D009132:Muscles / Q000032:analysis; D011343:Procaine / Q000008:administration & dosage / Q000627:therapeutic use*; D013552:Swine; D013997:Time Factors
D011343:Procaine; D003402:Creatine Kinase; D006221:Halothane