[Value of Soludactone in cardiac surgery in adults].
The use of potassium canrenoate (Soludactone) in the post-operative period in 31 patients who had undergone open-heart surgery, in comparison with a control batch of patients, led to a more rapid and easier regression of myocardial hyperexcitability, the maintenance of kaliemia at values near normal, a reduction in kaliuresis, a rapid elevation of the urinary Na/K ratio and the maintenance of satisfactory diuresis. But the majority of these effects appear progressively during the first 3 days of treatment, so potassium canrenoate should be prescribed 3 days before the intervention so that the beneficial effects may be manifested from the day of the intervention itself.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000517:prevention & control; D002191:Canrenoic Acid / Q000627:therapeutic use*; D006348:Cardiac Surgical Procedures; D004231:Diuresis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009318:Natriuresis; D011182:Postoperative Care; D011183:Postoperative Complications / Q000517:prevention & control; D011188:Potassium / Q000097:blood / Q000652:urine; D011245:Pregnadienes / Q000627:therapeutic use*; D011300:Preoperative Care; D012964:Sodium / Q000097:blood / Q000652:urine
D011245:Pregnadienes; D002191:Canrenoic Acid; D012964:Sodium; D011188:Potassium
Intérêt de la Soludactone en chirurgie cardiaque de l'adulte