[Na K ATPase changes in the erythrocyte membrane in subjects treated with inosine].
The effect of inosine on red cell membrane Na+K+ATPase in lead poisoning was studied in 13 subjects. In addition to enzyme damage, an appreciable increase in enzyme level was noted after 100 mg inosine i.m. for 20 days. It is felt that this form of management is useful in lead poisoning as a means of treating and preventing anaemia.
D000740:Anemia / Q000209:etiology / Q000517:prevention & control; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000201:enzymology*; D004912:Erythrocytes / Q000201:enzymology*; D006801:Humans; D007288:Inosine / Q000627:therapeutic use*; D007855:Lead Poisoning / Q000150:complications / Q000188:drug therapy* / Q000201:enzymology; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood*
D007288:Inosine; D000254:Sodium-Potassium-Exchanging ATPase
Modificazioni della Na +K+ATPasi di membrana nelle emazie di soggetti trattati con inosina.