title: Sister chromatid exchange in patients with viral disease.
abstract: Sister chromatid exchange (SCE) frequencies were studied in differentially stained chromosomes from lymphocytes of 17 patients with viral disease. The mean SCE score for the patients was 8.7 +/- 2.9 standard deviations. SCE scores were significantly elevated in the patients compared with the controls (p less than 0.01); however, variability in SCE means was observed in the patients. SCE elevations were also present in long term cultured Epstein Barr virus positive human B lymphocytes.
mesh_terms: D001402:B-Lymphocytes / Q000648:ultrastructure; D002460:Cell Line; D002478:Cells, Cultured; D004854:Herpesvirus 4, Human; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure*; D012854:Sister Chromatid Exchange; D014777:Virus Diseases / Q000235:genetics*