title: Antibodies to bovine leukemia virus in a leukosis dairy herd and suggestions for control of the infection.
abstract: A closed herd of 765 Holstein-Friesian dairy cattle with a history of multiple cases of leukosis was tested for antibodies to bovine leukemia virus by the bovine leukemia-glycoprotein immunodiffusion test. A total of 355 animals (46.4%) were antibody positive. Prevalence was 60% in the 373 milking cows and 100% in the breeding bulls. Antibodies were present in 59% of newborn calves. Prevalence of antibodies was higher in older animals and cows in second lactation had a higher prevalence than cows in first lactation (72% vs 43%). Proposed control measures in this herd aim at preventing infection of calves, heifers and lactating cows by: 1) separating them into groups negative and positive for bovine leukemia virus antibodies, 2) not allowing calves to receive colstrum or milk from infected cows and 3) by using seronegative bulls for natural breeding tested at three month intervals. Calves should be tested after six months of age. Before this time calves of positive mothers should be treated as being positive.
mesh_terms: D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D005260:Female; D007938:Leukemia / Q000276:immunology / Q000635:transmission / Q000662:veterinary*; D001909:Leukemia Virus, Bovine / Q000276:immunology*; D008297:Male; D011247:Pregnancy; D012190:Retroviridae / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral