The antifungal antibiotic sinefungin as a very active inhibitor of methyltransferases and of the transformation of chick embryo fibroblasts by Rous sarcoma virus.
D000241:Adenosine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D001358:Avian Sarcoma Viruses; D002460:Cell Line; D002472:Cell Transformation, Viral / Q000187:drug effects*; D002642:Chick Embryo; D005347:Fibroblasts / Q000378:metabolism; D007700:Kinetics; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D012435:S-Adenosylhomocysteine / Q000494:pharmacology; D012436:S-Adenosylmethionine / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000935:Antifungal Agents; D012436:S-Adenosylmethionine; D012435:S-Adenosylhomocysteine; D008780:Methyltransferases; D000241:Adenosine