[Avoidance learning in rats treated with estrogens].
Male and female rats were treated with estradiol benzoate in the 5 degrees day of life. The avoidance conditioning, tested after 65 days, was significatively impaired in males treated with estradiol, a significative retardation was observed in females treated, but no significant end-difference versus no-treated females. It is supposed that a hormone induced synaptic shaft/spines ratio in preoptic area may be involved in avoidance conditioning.
D000679:Amygdala / Q000187:drug effects; D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D006062:Gonadotropins / Q000378:metabolism; D008297:Male; D011301:Preoptic Area / Q000187:drug effects; D051381:Rats; D017981:Receptors, Neurotransmitter / Q000187:drug effects; D012737:Sex Factors
D006062:Gonadotropins; D017981:Receptors, Neurotransmitter; D004958:Estradiol
Condizionamento di evitamento in ratti trattati conestrogeni.