[Bronchial arteriography and intraarterial chemotherapy in bronchogenic carcinoma (author's transl)].
Selective bronchial angiography and short term intra-arterial infusions of Mitomycin C were performed in 70 patients with bronchogenic carcinoma. The courses were given 1--5 times with a median interval of 2 weeks. The angiograms were compared with chest radiograms and data obtained at bronchoscopy, mediastinoscopy, surgery or autopsy. The effect of therapy was evaluated with chest radiography and bronchoscopy. Among our first 36 patients an objective response was registered in 18/27 patients with squamous cell carcinoma, in 4/7 with adenocarcinoma and in 2/2 with small cell cancer. These results warrant further studies. Though not suitable as a routine procedure in the diagnostic work up of a patient with possible bronchogenic carcinoma bronchial angiogrpahy may contribute to a better staging when used e.g. in connection with intraarterial chemotherapy.
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000188:drug therapy; D000792:Angiography; D001981:Bronchial Arteries / Q000000981:diagnostic imaging*; D002283:Carcinoma, Bronchogenic / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D018288:Carcinoma, Small Cell / Q000000981:diagnostic imaging / Q000188:drug therapy; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000188:drug therapy; D006801:Humans; D007261:Infusions, Intra-Arterial; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D008937:Mitomycins / Q000008:administration & dosage* / Q000627:therapeutic use
D008937:Mitomycins
Bronchialangiographie und intraarterielle Chemotherapie bei Bronchuskarzinom.