[Adsorption properties of Beidellite (author's transl)].
The beidellite is both an activator and an adsorbing agent for certain clotting factors: at low concentration (1 p. 1 000), factors XII and VII of human plasma are activated. At a concentration of 10 p. 1 000, the fibrinogen is totally adsorbed, leaving in the supernatant most of the VIII. At alpha 20 p. 1 000 concentrations, most of factor II remains unabsorbed, the remaining plasma being devoided of other clotting factors except minute amounts of factors XI and XII. Contrarely to bentonite, which has similar properties, beidellite does not absorb water and does not modify the pH. Beidellite is therefore a very useful agent for selective adsorption of clotting factors.
D000327:Adsorption; D000538:Aluminum Silicates / Q000378:metabolism*; D001779:Blood Coagulation Factors; D001780:Blood Coagulation Tests; D004305:Dose-Response Relationship, Drug; D005164:Factor IX / Q000378:metabolism; D005165:Factor V / Q000378:metabolism; D005167:Factor VII / Q000378:metabolism; D005169:Factor VIII / Q000378:metabolism; D005170:Factor X / Q000378:metabolism; D005172:Factor XI / Q000378:metabolism; D005174:Factor XII / Q000378:metabolism; D005340:Fibrinogen / Q000032:analysis / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010714:Phosphatidylethanolamines / Q000378:metabolism; D011516:Prothrombin / Q000378:metabolism; D013917:Thrombin / Q000378:metabolism
D000538:Aluminum Silicates; D001779:Blood Coagulation Factors; D010714:Phosphatidylethanolamines; D005165:Factor V; D005167:Factor VII; D011516:Prothrombin; D005169:Factor VIII; D005164:Factor IX; D005170:Factor X; D005174:Factor XII; D005340:Fibrinogen; D005172:Factor XI; D013917:Thrombin
Etude des propriétés adsorbantes de la beidellite