title: Regulation of the lysine biosynthetic pathway in Escherichia coli K-12: isolation of a cis-dominant constitutive mutant for AK III synthesis.
abstract: A method for isolating regulatory mutants for the synthesis of lysine biosynthetic enzymes in Escherichia coli is described. One of them is identified as a cis-dominant constitutive mutant for the synthesis of the lysine-sensitive asportokinase AK III (lysC gene).
mesh_terms: D000483:Alleles; D001120:Arginine / Q000378:metabolism; D001222:Aspartate Kinase / Q000096:biosynthesis* / Q000378:metabolism; D001223:Aspartate-Semialdehyde Dehydrogenase / Q000096:biosynthesis; D001431:Bacteriological Techniques; D002874:Chromosome Mapping; D003090:Coliphages; D003227:Conjugation, Genetic; D004305:Dose-Response Relationship, Drug; D004794:Enzyme Repression; D004926:Escherichia coli / Q000201:enzymology* / Q000254:growth & development / Q000302:isolation & purification; D005144:F Factor; D005799:Genes, Dominant; D008239:Lysine / Q000096:biosynthesis* / Q000378:metabolism; D009154:Mutation; D010770:Phosphotransferases / Q000096:biosynthesis*; D013045:Species Specificity; D014161:Transduction, Genetic
chemical_list: D001120:Arginine; D001223:Aspartate-Semialdehyde Dehydrogenase; D010770:Phosphotransferases; D001222:Aspartate Kinase; D008239:Lysine