[Donnan equilibrium and kinetics of uric acid transport across human erythrocyte membrane].
The study of the effects of varying pH and ionic composition of external solution on the uric acid ratio (see article) for human erythrocytes at equilibrium and on its permeability constant shows that the distribution of uric acid agrees with the laws of the Gibbs-Donnan equilibrium and its passage across the human erythrocyte membrane with the law of ionic diffusion.
D001565:Benzoates / Q000494:pharmacology; D001692:Biological Transport / Q000187:drug effects; D002462:Cell Membrane / Q000378:metabolism*; D002463:Cell Membrane Permeability; D004139:Dinitrofluorobenzene / Q000494:pharmacology; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010653:Phenylbutazone / Q000494:pharmacology; D012980:Sodium Salicylate / Q000494:pharmacology; D014527:Uric Acid / Q000097:blood*
D001565:Benzoates; D014527:Uric Acid; D004139:Dinitrofluorobenzene; D010653:Phenylbutazone; D012980:Sodium Salicylate
Equilibre de Donnan et cinétique du transport de l'acide urique par la membrane de l'hématie humaine