title: The ecology of gonococcal plasmids.
abstract: Of 261 strains of Neisseria gonorrhoeae examined for plasmids, 6 were plasmid-free, 217 contained only a small multicopy 2.6 X 10(6) dalton plasmid and 38 carried a large 24.5 X 10(6) dalton plasmid. Restriction enzyme digests and DNA-DNA hybridization studies revealed that the large plasmids isolated between 1940 and 1978 share a common core of DNA sequences (70 to 100%) and represent a group of closely related molecules.
mesh_terms: D001483:Base Sequence; D004262:DNA Restriction Enzymes / Q000378:metabolism; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics*; D004270:DNA, Circular / Q000032:analysis / Q000235:genetics*; D006069:Gonorrhea / Q000382:microbiology; D006801:Humans; D009344:Neisseria gonorrhoeae / Q000032:analysis / Q000235:genetics*; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D010957:Plasmids
chemical_list: D004269:DNA, Bacterial; D004270:DNA, Circular; D004262:DNA Restriction Enzymes