The effect of DDT on vitamin D metabolism and calcium binding activity in the chick.
The mechanism of DDT impaired calcium absorption was studied in control, DDT fed and starved chicks. The metabolism of [3H]cholecalciferol was the same in the 3 groups, but the DDT fed and starved chicks had less intestinal calcium binding activity than the control chicks. These results suggest that DDT impaired calcium absorption and intestinal calcium binding activity may be a result of DDT induced anorexia.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002645:Chickens; D002762:Cholecalciferol / Q000378:metabolism; D003634:DDT / Q000494:pharmacology*; D004032:Diet; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism; D013217:Starvation / Q000378:metabolism; D014807:Vitamin D / Q000378:metabolism*
D014807:Vitamin D; D002762:Cholecalciferol; D003634:DDT; D002118:Calcium