title: Secondary structure prediction of anterior pituitary hormones. Lack of correlation between predicted values and circular dichroism data.
abstract: The secondary structures of human somatotropin, human choriomammotropin, ovine and porcine prolactin, human, ovine and porcine beta-lipotropin, human and ovine lutropin, human thyrotropin, human corticotropin, alpha-melanotropin and human beta-melanotropin have been predicted by the method of Chou & Fasman. Predicted contents of alpha-helix and beta-sheet do not correspond well with values estimated from circular dichroism spectra.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000032:analysis; D000818:Animals; D002942:Circular Dichroism; D013006:Growth Hormone / Q000032:analysis; D006801:Humans; D007986:Luteinizing Hormone / Q000032:analysis; D009074:Melanocyte-Stimulating Hormones / Q000032:analysis; D010908:Pituitary Hormones, Anterior / Q000032:analysis*; D011388:Prolactin / Q000032:analysis; D011487:Protein Conformation; D012756:Sheep; D013552:Swine; D013972:Thyrotropin / Q000032:analysis; D008083:beta-Lipotropin / Q000032:analysis
chemical_list: D010908:Pituitary Hormones, Anterior; D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D007986:Luteinizing Hormone; D013972:Thyrotropin; D013006:Growth Hormone; D009074:Melanocyte-Stimulating Hormones; D008083:beta-Lipotropin