Radiation effects on rat testes. IX. Studies on oxidative enzymes after partial body gamma irradiation.
Oxidative enzymes in the rat testes have been studied after gamma irradiation. The role of these enzymes in relation to spermatogenesis and steroidogenesis after radiation injury to testis has been discussed. Loss of succinic dehydrogenase and sorbitol dehydrogenase reflects the losts of germ cell population. Malic enzyme and malic dehydrogenase seem to the related to the deficiency of steroid hormones, whereas increase in glucose-6-phosphate dehydrogenase and NADP isocitric dehydrogenase is due to secondary stimulation of pituitary.
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis; D007521:Isocitrate Dehydrogenase / Q000032:analysis; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008291:Malate Dehydrogenase / Q000032:analysis; D008297:Male; D009249:NADP / Q000032:analysis; D010088:Oxidoreductases / Q000528:radiation effects*; D011506:Proteins / Q000032:analysis; D011830:Radiation Effects; D051381:Rats; D013012:Sorbitol; D013091:Spermatogenesis / Q000528:radiation effects; D013094:Spermatozoa / Q000528:radiation effects; D013256:Steroids / Q000096:biosynthesis; D013385:Succinate Dehydrogenase / Q000032:analysis; D013737:Testis / Q000201:enzymology / Q000528:radiation effects*; D013997:Time Factors
D011506:Proteins; D013256:Steroids; D013012:Sorbitol; D009249:NADP; D010088:Oxidoreductases; D007770:L-Lactate Dehydrogenase; D008291:Malate Dehydrogenase; D007521:Isocitrate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D013385:Succinate Dehydrogenase