[Cardiotropic effects of luliberin. Effects of luliberin on the activities of phosphorylase A and ornithine decarboxylase and concentration of 3', 5'-AMP].
The level of luliberin, the luteinizing hormone-releasing hormone (LH-RH), and the possibility of the hormonal control of metabolic and biosynthetic processes in the heart were studied. It was shown that the rat heart contains a factor, which is immunochemically and chromatographically related to LH-RH (19--46 picograms per organ). Intraperitoneal injection of LH-RH increases the activities of phosphorylase A and ornithine decarboxylase and the concentration of 3',5'-AMP and potentiates the stimulating effect of adrenaline on ornithine decarboxylase.
D000818:Animals; D002262:Carboxy-Lyases / Q000378:metabolism*; D000242:Cyclic AMP / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects; D009206:Myocardium / Q000378:metabolism*; D009955:Ornithine Decarboxylase / Q000378:metabolism*; D010762:Phosphorylase a / Q000378:metabolism*; D006005:Phosphorylases / Q000378:metabolism*; D051381:Rats
D007987:Gonadotropin-Releasing Hormone; D000242:Cyclic AMP; D010762:Phosphorylase a; D006005:Phosphorylases; D002262:Carboxy-Lyases; D009955:Ornithine Decarboxylase
Kardiotropnoe deĭstvie liuliberina. Vliianie na aktivnost' fosforila3y A, ornitindekarboksila3y i kontsentratsiius 3': 5'-AMP.