Effect of sodium cellulose phosphate therapy on crystallization of calcium oxalate in urine.
Effects of oral sodium cellulose phosphate therapy (5 g three times a day with meals for 4 days) on renal excretion of oxalate and on the crystallization of calcium oxalate in urine were examined in six patients with absorptive hypercalciuria on a constant metabolic dietary regimen. During treatment, urinary oxalate increased by 9-50 mg/day. However, urinary calcium decreased by 138-225 mg/day (50%-70%). Thus, the state of saturation of urine with respect to calcium oxalate decreased or did not change significantly. There was no consistent or significant change in the formation product ratio (limit of metastability) or in the crystal growth of calcium oxalate in urine.
D000284:Administration, Oral; D002118:Calcium / Q000652:urine*; D002411:Cation Exchange Resins / Q000627:therapeutic use*; D002482:Cellulose / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use; D003460:Crystallization; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006934:Hypercalcemia / Q000188:drug therapy*; D007475:Ion Exchange Resins / Q000627:therapeutic use*; D009943:Organophosphorus Compounds / Q000008:administration & dosage / Q000627:therapeutic use; D010070:Oxalates / Q000652:urine*; D010710:Phosphates / Q000652:urine; D014556:Urine
D002411:Cation Exchange Resins; D007475:Ion Exchange Resins; D009943:Organophosphorus Compounds; D010070:Oxalates; D010710:Phosphates; D002482:Cellulose; C008881:phosphocellulose; D002118:Calcium