Comparative thermometric coagulation studies of plasmas from normal outbred Swiss Webster mice and persons.
The functional capabilities of a thermometric clot-timer have been demonstrated in a comparative study of human and mouse plasma coagulation. The influence of some variables on coagulation times of mouse and human plasmas were examined in activated partial thromboplastin time, one-stage prothrombin time, and Russell's viper venom time assays. Mouse plasma coagulation times were generally shorter and more reproducible than those of human plasma. Optimal assay conditions are also described.
D000818:Animals; D001780:Blood Coagulation Tests / Q000295:instrumentation / Q000379:methods / Q000662:veterinary*; D002122:Calcium Chloride / Q000494:pharmacology; D006801:Humans; D051379:Mice / Q000097:blood*; D010714:Phosphatidylethanolamines / Q000494:pharmacology; D011517:Prothrombin Time / Q000662:veterinary; D012822:Silicon Dioxide; D012965:Sodium Chloride / Q000494:pharmacology; D013696:Temperature; D014757:Viper Venoms
D010714:Phosphatidylethanolamines; D014757:Viper Venoms; D012965:Sodium Chloride; D012822:Silicon Dioxide; D002122:Calcium Chloride