Inactivation of enterovirus by glutaraldehyde.
A study on the rate of inactivation by glutaraldehyde of coxsackievirus was conducted using different concentrations, temperatures, and pH values. It was found, that 2 percent glutaraldehyde at pH 7.4 and 25 C, as recommended for a sporicide, reduced the titer of infectious virus by 2 log10U in 1 min or less. The reduction was not negatively affected by high concentrations of organic matter (serum and animal spillings) in the reaction mixtures.
D000447:Aldehydes / Q000494:pharmacology*; D000818:Animals; D001798:Blood Proteins; D002417:Cattle; D003470:Culture Media; D003588:Cytopathogenic Effect, Viral; D004770:Enterovirus / Q000187:drug effects*; D005976:Glutaral / Q000494:pharmacology*; D006367:HeLa Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D051379:Mice; D013696:Temperature; D014556:Urine; D014776:Virus Cultivation
D000447:Aldehydes; D001798:Blood Proteins; D003470:Culture Media; D005976:Glutaral