The nature of the effector cells of cell-mediated immune responses to Sendai and Kunz virus infections in mice.
The development of virus-specific cell-mediated immune (CMI) responses to Sendai and Kunz virus infections of the respiratory tract of mice is described. In addition a heterotypic cell-mediated immune response develops during each of the virus infections. Cell depletion studies indicate that the effector cells of the virus-specific CMI responses are theta antigen bearing T lymphocytes. Similar studies of the heterotypic responses suggest that 2 cell types are involved, T lymphocytes and NK cells.
D000818:Animals; D003602:Cytotoxicity, Immunologic; D007111:Immunity, Cellular; D008264:Macrophages / Q000276:immunology; D051379:Mice; D009975:Orthomyxoviridae / Q000276:immunology; D010222:Parainfluenza Virus 1, Human / Q000276:immunology; D018184:Paramyxoviridae Infections / Q000276:immunology*; D012141:Respiratory Tract Infections / Q000276:immunology; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology; D013934:Thymectomy; D013997:Time Factors