title: Endometrial hyperplasia: a five-year study.
abstract: Because of the recent controversy concerning estrogen and endometrial cancer, we studied the possible potential precursor lesions of the endometrium, reviewing 263 patients hospitalized in a community teaching hospital. The estrogen hormonal status, either exogenously or endogenously produced, plays a large role in the histologic structure of the uterine endometrium and may lead to difficulty in determining the exact histologic diagnosis or its potential to progress to endometrial adenocarcinoma.
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis; D000293:Adolescent; D000328:Adult; D000368:Aged; D004714:Endometrial Hyperplasia / Q000139:chemically induced / Q000175:diagnosis*; D004966:Estrogens, Conjugated (USP) / Q000009:adverse effects; D005260:Female; D006801:Humans; D008875:Middle Aged; D011230:Precancerous Conditions / Q000175:diagnosis*; D014594:Uterine Neoplasms / Q000175:diagnosis
chemical_list: D004966:Estrogens, Conjugated (USP)