Lack of alpha-adrenergic component in the chronotrophic action of serotonin on isolated atrium of hamster.
Effects of serotonin on alpha-adrenergic receptors of isolated hamsters' atria preparation were investigated. The positive chronotropic effect of serotonin on isolated atria of the hamster is not related with postsynaptic alpha-adrenergic receptors.
D000818:Animals; D006224:Cricetinae; D004347:Drug Interactions; D005260:Female; D006321:Heart / Q000294:innervation; D006339:Heart Rate / Q000187:drug effects*; D066298:In Vitro Techniques; D008297:Male; D008729:Methoxamine / Q000494:pharmacology; D010646:Phentolamine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D011941:Receptors, Adrenergic / Q000187:drug effects*; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects*; D012701:Serotonin / Q000494:pharmacology*
D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D012701:Serotonin; D011433:Propranolol; D008729:Methoxamine; D010646:Phentolamine