[Suppressor effect induced by sodium periodate on the antibody response of mouse splenic cells in vitro : inhibition of this effect by sodium borohydride].
Mild oxidation of mouse spleen cells by sodium periodate induces blastogenesis. Concomitantly, the in vitro response of these cells to sheep red blood cells is inhibited. Exposure of spleen cells to sodium borohydride following periodate treatment reduces blastogenesis and restores the immune response.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D001894:Borohydrides / Q000494:pharmacology*; D066298:In Vitro Techniques; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects* / Q000276:immunology; D008297:Male; D051379:Mice; D008811:Mice, Inbred DBA; D010504:Periodic Acid / Q000494:pharmacology*; D013154:Spleen / Q000166:cytology / Q000187:drug effects* / Q000276:immunology
D001894:Borohydrides; D010504:Periodic Acid
Effet suppresseur induit par le periodate de sodium sur la réponse anticorps des cellules spléniques de souris in vitro : inhibition de cet effet par le borohydrure de sodium.