title: Sex-dependent action of prenatal fractionated X-irradiation in the mouse. Biochemical findings.
abstract: X-irradiation of pregnant NMRI-mice on gestational days 11-13 with 3 x 10.5 Gy increased postnatal mortality of the female offspring only. Weights, protein content and acetylcholinesterase, as well as Na,K-ATPase activities in the brains of all treated offspring, were changed. There were, however, no differences between females and males with respect to these parameters.
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism* / Q000528:radiation effects; D000818:Animals; D001921:Brain / Q000378:metabolism / Q000528:radiation effects*; D005260:Female; D005333:Fetus / Q000528:radiation effects*; D008297:Male; D051379:Mice; D009419:Nerve Tissue Proteins / Q000378:metabolism* / Q000528:radiation effects; D011247:Pregnancy; D012737:Sex Factors; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism* / Q000528:radiation effects
chemical_list: D009419:Nerve Tissue Proteins; D000110:Acetylcholinesterase; D000254:Sodium-Potassium-Exchanging ATPase