title: Rheumatoid arthritis associated with hyperviscosity syndrome and intermediate complex formation.
abstract: A patient with long-standing rheumatoid arthritis developed hyperviscosity syndrome that correlated with the presence of abundant intermediate complexes in plasma. The intermediate complexes were isolated, and evidence is presented that these complexes are composed predominantly of igG-rheumatoid factor.
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications*; D001796:Blood Protein Disorders / Q000150:complications*; D001797:Blood Protein Electrophoresis; D001798:Blood Proteins / Q000032:analysis; D001809:Blood Viscosity; D005260:Female; D006474:Hemorrhagic Disorders; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007074:Immunoglobulin G / Q000302:isolation & purification*; D009461:Neurologic Manifestations; D010953:Plasma Volume; D012164:Retinal Diseases; D012217:Rheumatoid Factor / Q000302:isolation & purification*; D013577:Syndrome
chemical_list: D001798:Blood Proteins; D007074:Immunoglobulin G; D012217:Rheumatoid Factor