title: The clinical diagnosis of insulinoma.
abstract: Based on the literature and on experience and on experience with 23 cases the clinical diagnosis of insulinomas is reviewed. In clinical praxis the diagnostic steps can usually be simplified to a demonstration of fasting, symptomatic hypoglycaemia. Hence, we have used the 72-hour fast as the single diagnostic test for insulinomas during the last 5 years. Pro-insulin measurements may be a valuable supplementary tool. Other diagnostic tests are probably of little importance.
mesh_terms: D007516:Adenoma, Islet Cell / Q000097:blood / Q000175:diagnosis*; D001786:Blood Glucose / Q000032:analysis; D005215:Fasting; D005934:Glucagon; D006801:Humans; D007328:Insulin / Q000097:blood / Q000378:metabolism; D000078790:Insulin Secretion; D007930:Leucine; D010190:Pancreatic Neoplasms / Q000097:blood / Q000175:diagnosis*
chemical_list: D001786:Blood Glucose; D007328:Insulin; D005934:Glucagon; D007930:Leucine