title: Altered nuclear structure during productive and abortive infections with SV40 DNA.
abstract: A striking alteration in nuclear morphology, detected by simian virus 40 (SV40) large-T antigen-specific immunofluorescence, occurred in cells infected by form I SV40 DNA but not by SV40 virions. This alteration did not require viral or cellular DNA synthesis.
mesh_terms: D000310:Adrenal Gland Neoplasms; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002460:Cell Line; D002467:Cell Nucleus / Q000276:immunology / Q000648:ultrastructure*; D004279:DNA, Viral; D005455:Fluorescent Antibody Technique; D000882:Haplorhini; D006801:Humans; D007668:Kidney; D008168:Lung / Q000196:embryology; D051379:Mice; D013539:Simian virus 40 / Q000254:growth & development / Q000276:immunology
chemical_list: D000956:Antigens, Viral; D004279:DNA, Viral