Restriction of resistance transfer in Staphylococcus aureus.
The transduction frequency of wild type resistance plasmids carrying the modification of a defined donor strain into a series of acceptor strains with different restriction systems and into restriction-deficient mutants was studied. Plasmids carrying resistance to tetracycline, chloramphenicol and penicillin were in general as sensitive as the transducing phage to restriction and modification. Plasmids carrying penicillinase of type A and C could be transferred into strains of group II.
D002701:Chloramphenicol; D004262:DNA Restriction Enzymes / Q000235:genetics; D004352:Drug Resistance, Microbial; D005796:Genes; D010403:Penicillin Resistance; D010957:Plasmids; D013211:Staphylococcus aureus / Q000235:genetics*; D013752:Tetracycline; D014161:Transduction, Genetic
D002701:Chloramphenicol; D004262:DNA Restriction Enzymes; D013752:Tetracycline