Uptake of 67Cu by ceruloplasmin in vitro.
Solutions of human ceruloplasmin, in Tris buffer at pH values between 6 and 7.5, readily took up carrier-free 67Cu2+, but only when the substrate, rho-phenylenediamine, was added.
D002021:Buffers; D002570:Ceruloplasmin / Q000378:metabolism*; D003300:Copper / Q000378:metabolism* / Q000494:pharmacology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010655:Phenylenediamines; D011868:Radioisotopes
D002021:Buffers; D010655:Phenylenediamines; D011868:Radioisotopes; D003300:Copper; D002570:Ceruloplasmin