title: Acid-base and electrolyte balance in infants of diabetic mothers. Vaginal delivery versus caesarean section.
abstract: The acid-base and electrolyte balance of 30 women studied at delivery and in their infants during the first 48 h. 18 women were diabetics, 10 of these were delivered vaginally (DMvag) and 8 by elective caesarean section (DMcs). 12 healthy women were vaginally delivered (HMvag). The infants of diabetic mothers (IDM) received active infusion therapy. At birth the DMvag and their infants (IDMvag) had a more pronounced metabolic acidosis than the DMcs and their babies (IDMcs). The largest metabolic acidosis occurred, however, in the group of HMvag and their infants (IHMvag). After birth no significant differences were obtained in the acid-base and electrolyte balance between IDMvag and IDMcs. The plasma potassium level remained lower in IDM than in IHM. The study stress the importance of adequate management of diabetes in pregnancy in combination with active intravenous therapy during delivery and to the infant in the immediate neonatal period. The slightly larger metabolic acidosis seen in combination with vaginal delivery suggests that this mode of delivery should not be attempted uncritically in diabetic women.
mesh_terms: D000136:Acid-Base Equilibrium; D000328:Adult; D001639:Bicarbonates / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D001798:Blood Proteins / Q000378:metabolism; D002118:Calcium / Q000097:blood; D002245:Carbon Dioxide / Q000097:blood; D002585:Cesarean Section; D002712:Chlorides / Q000097:blood; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D007743:Labor, Obstetric; D007773:Lactates / Q000097:blood; D008274:Magnesium / Q000097:blood; D008431:Maternal-Fetal Exchange; D010313:Partial Pressure; D010758:Phosphorus / Q000097:blood; D011188:Potassium / Q000097:blood; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood*; D012964:Sodium / Q000097:blood; D014882:Water-Electrolyte Balance
chemical_list: D001639:Bicarbonates; D001786:Blood Glucose; D001798:Blood Proteins; D002712:Chlorides; D007773:Lactates; D002245:Carbon Dioxide; D010758:Phosphorus; D012964:Sodium; D008274:Magnesium; D011188:Potassium; D002118:Calcium