title: Common exposure outbreak of gastroenteritis due to type 2 rotavirus with high secondary attack rate within families.
abstract: A sharp outbreak of gastroenteritis associated with human rotavirus type 2 involved not only all of nine infants and young children in a playgroup but also seven of 10 parents and grandparents studied. The source of the outbreak appeared to be two non-playgroup siblings. Six of 11 individuals studied shed human rotavirus type 2, and each of seven from whom paired sera were obtained developed a type 2 sero-response. Overall, evidence of infection with rotavirus type 2 was demonstrated in 10 of 11 individuals by detection of virus in stools and/or a serologic response in an enzyme-linked immunosorbent assay.
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000453:epidemiology*; D005243:Feces / Q000382:microbiology; D005759:Gastroenteritis / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D006801:Humans; D007223:Infant; D012328:RNA Viruses / Q000302:isolation & purification*; D012401:Rotavirus / Q000302:isolation & purification*; D014768:Virginia; D014777:Virus Diseases / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D000914:Antibodies, Viral