Adrenal-testis interaction in the stallion.
The authors describe the short and long term effects of synthetic adrenocorticotrophin and of cortisol on peripheral plasma testosterone concentrations in 2 stallions. A single injection of either hormone temporarily raised plasma testosterone concentrations but repeated injection (twice daily for 5 days) depressed plasma testosterone concentrations. Cessation of treatment was followed by a rise in plasma testosterone to concentrations higher than those in the pretreatment period. These findings are briefly discussed.
D000311:Adrenal Glands / Q000378:metabolism*; D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D006736:Horses / Q000097:blood / Q000502:physiology*; D006854:Hydrocortisone / Q000008:administration & dosage / Q000494:pharmacology*; D007275:Injections, Intravenous; D008297:Male; D013737:Testis / Q000378:metabolism*; D013739:Testosterone / Q000097:blood*
D013739:Testosterone; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone