Mechanism of liquefaction of the human ejaculate. II. Role of collagenase-like peptidase and seminal proteinase.
Collagenase-like peptidase and seminal proteinase were isolated from human testis and human seminal plasma. The effects of both enzymes upon proteins isolated from the human ejaculate were studied. Both enzymes degraded ejaculate proteins. The data suggest that collagenase-like peptidase is responsible for the first, and seminal proteinase for the second, phase of human ejaculate liquefaction in vitro.
D002850:Chromatography, Gel; D006801:Humans; D008297:Male; D003012:Microbial Collagenase / Q000378:metabolism / Q000502:physiology*; D008970:Molecular Weight; D010447:Peptide Hydrolases / Q000378:metabolism / Q000502:physiology*; D011506:Proteins / Q000378:metabolism; D012661:Semen / Q000201:enzymology / Q000502:physiology*; D013737:Testis / Q000201:enzymology
D011506:Proteins; D010447:Peptide Hydrolases; D003012:Microbial Collagenase