Beta-mimetic drugs and possible prevention of respiratory distress syndrome.
The prophylactic value of beta-mimetic drugs in preventing respiratory distress syndrome (RDS) is investigated by comparing 29 preterm infants of ritodrine treated mothers with 34 preterm infants of a control group. Five cases of RDS (17 per cent) occurred among the infants of treated mothers as compared with 12 cases (35 per cent) in the control group (p = 0-09). The difference is, however, statistically significant for the group of infants weighing less than 2300 grams (p = 0-01) which includes all infants affected with RDS.
D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D001034:Apgar Score; D001724:Birth Weight; D002986:Clinical Trials as Topic; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011412:Propanolamines / Q000627:therapeutic use*; D012127:Respiratory Distress Syndrome, Newborn / Q000517:prevention & control*; D012189:Retrospective Studies; D012312:Ritodrine / Q000627:therapeutic use*
D000318:Adrenergic beta-Agonists; D011412:Propanolamines; D012312:Ritodrine