Glucose-6-phosphate-dependent pyruvate kinase in Streptococcus mutans.
Pyruvate kinase of Streptococcus mutans JC 2 had an absolute and specific requirement for glucose-6-phosphate. Inorganic phosphate was a strong inhibitor. The enzyme required K+ or NH4+ and Mg2+ or Mn2+. S. mutans FIL and E 49, Streptococcus bovis ATCC 9809, and Streptococcus salivarius ATCC 13419 had also glucose-6-phosphate-dependent pyruvate kinases, whereas Streptococcus sanguis NCTC 10904 had an enzyme activated by fructose-1,6-diphosphate.
D000641:Ammonia / Q000378:metabolism; D002474:Cell-Free System; D005958:Glucosephosphates / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D008274:Magnesium / Q000378:metabolism; D008345:Manganese / Q000378:metabolism; D010710:Phosphates / Q000494:pharmacology; D010728:Phosphoenolpyruvate / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D011770:Pyruvate Kinase / Q000378:metabolism*; D013045:Species Specificity; D013291:Streptococcus / Q000201:enzymology*; D013295:Streptococcus mutans / Q000201:enzymology*
D005958:Glucosephosphates; D010710:Phosphates; D008345:Manganese; D010728:Phosphoenolpyruvate; D000641:Ammonia; D011770:Pyruvate Kinase; D008274:Magnesium; D011188:Potassium