Isolation of two new related peptide antibiotics, cerexins A and B (studies on antibiotics from the genus Bacillus. I).
Two new antibiotics cerexins A and B were isolated from different strains identified with Bacillus cereus. These two antibiotics are amphoteric in nature, soluble in particular solvents such as dimethylsulfoxide, dimethylformamide and alkaline water, and show typical infrared absorptions of peptide. These also have similar antimicrobial properties active against gram-postive bacteria.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001409:Bacillus cereus / Q000032:analysis*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D051379:Mice; D010455:Peptides / Q000302:isolation & purification / Q000494:pharmacology; D013210:Staphylococcus / Q000187:drug effects; D013296:Streptococcus pneumoniae / Q000187:drug effects; D013297:Streptococcus pyogenes / Q000187:drug effects
D000900:Anti-Bacterial Agents; D010455:Peptides