Extreme duct papillomatosis of the juvenile breast.
Three cases of peculiar and very severe ductal papillomatosis of the breast are reported. This ductal papillomatosis was unusual, both in its histological architecture and in occurring in juveniles, viz. girls aged 11, 14, and 17 years. In two of the patients breast cancer was diagnosed 27 and 11 years later. In one of them the ductal papillomatosis must be presumed to have been precancerosis, while in the other patient there was possibly from the outset an unusually papilliferous, intraductal carcinoma of low malignancy.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D002648:Child; D004848:Epithelium / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008408:Mastectomy; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary; D010212:Papilloma / Q000473:pathology* / Q000601:surgery; D011230:Precancerous Conditions / Q000473:pathology*