Distribution of herpes simplex virus in acute necrotising encephalitis.
A 49-yr-old female developed a rapidly progressive neurological illness. The gross, light microscopic and electron-microscopic examination of the brain revealed all of the characteristic features of acute necrotising encephalitis with predominant involvement of the left limbic system. The distribution of herpes simplex virus suggests that the olfactory apparatus is the route of infection.
D000208:Acute Disease; D001921:Brain / Q000473:pathology; D004660:Encephalitis / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D005260:Female; D006561:Herpes Simplex / Q000473:pathology*; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D009336:Necrosis; D009830:Olfactory Bulb / Q000382:microbiology / Q000648:ultrastructure; D018139:Simplexvirus / Q000502:physiology