Evaluation of virucidal compounds for inactivation of rhinovirus on hands.
Antimicrobial liquids and foams were applied to the hands to determine their virucidal activity against rhinoviruses. Dilute solutions (1%) of iodine in ethyl alcohol or in water were most effective in causing inactivation of rhinovirus when applied immediately after viral contamination. Iodine also had a residual virucidal activity which persisted on the hands for up to 1 h. Less effective inactivation of rhinovirus was observed with foams containing 0.23% hexachlorophene and 58% ethyl alcohol and another containing 0.2% benzalkonium chloride and 50% ethyl alcohol. Ethyl alcohol alone or in a mixture with benzyl alcohol was the least effective preparation tested.
D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D006225:Hand / Q000382:microbiology*; D006801:Humans; D007455:Iodine / Q000008:administration & dosage / Q000494:pharmacology; D012229:Rhinovirus / Q000187:drug effects*
D000891:Anti-Infective Agents, Local; D007455:Iodine