Ultrastructural changes in rat liver cells induced by Proteus mirabilis endotoxin.
Changes in individual organella of rat hepatocytes developing under the effect of Proteus mirabilis endotoxin (Pme) were observed under electron microscope. The effect of drugs which diminish liver cell injury by Pme (polymyxin, cholestyramine and hydrocortisone) on the changes was studied.
D000818:Animals; D001427:Bacterial Toxins / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D002792:Cholestyramine Resin / Q000494:pharmacology; D004731:Endotoxins / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D006854:Hydrocortisone / Q000494:pharmacology; D008099:Liver / Q000187:drug effects* / Q000648:ultrastructure; D008297:Male; D011113:Polymyxins / Q000494:pharmacology; D011513:Proteus mirabilis; D051381:Rats
D001427:Bacterial Toxins; D004731:Endotoxins; D011113:Polymyxins; D002792:Cholestyramine Resin; D006854:Hydrocortisone