Globin gene expression in MSV-transformed fibroblasts.
The activation of globin gene expression on viral transformation of 3T3 cells was investigated. Globin mRNA was determined using a radioactive complementary DNA probe. No difference was found between 3T3 and transformed 3T3 cells. There does not therefore appear to be a random activation of extensive regions of the cellular genome.
D000818:Animals; D002460:Cell Line; D002472:Cell Transformation, Viral; D005914:Globins / Q000096:biosynthesis*; D007700:Kinetics; D051379:Mice; D009693:Nucleic Acid Hybridization; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism; D009053:Sarcoma Viruses, Murine; D014158:Transcription, Genetic
D012333:RNA, Messenger; D005914:Globins