Effect of silicic acid on surface potential of erythrocytes.
A potential-generating effect of ortho-silicic acid on the surface potentials of erythrocyte membranes was demonstrated by a potentiometric method using platinum electrodes. With concentration rising from 10(-7) to 10(-4) the silicic acid reduced potential of washed erythrocytes which reached the final concentration a value about 36 mV. Higher concentrations of acid caused haemolysis.
D000328:Adult; D004305:Dose-Response Relationship, Drug; D004910:Erythrocyte Membrane / Q000187:drug effects*; D004912:Erythrocytes / Q000187:drug effects*; D005260:Female; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects; D011199:Potentiometry / Q000379:methods; D012824:Silicic Acid / Q000494:pharmacology*; D012822:Silicon Dioxide / Q000494:pharmacology*
D012824:Silicic Acid; D012822:Silicon Dioxide