title: Starfish and horseshoe crab egg factors cause elevations of cyclic nucleotide concentrations in spermatozoa from starfish and horseshoe crabs.
abstract: Factors collected from the eggs of the starfish (Pisaster giganteus) and the horsehoe crab (Limulus polyphemus) caused significant increases in the sperm cyclic nucleotide concentrations of the respective species. Sea urchin egg factors, at concentrations that resulted in maximal cyclic nucleotide elevations in sea urchin spermatozoa, had no effect on those of starfish or horseshoe crab, suggesting a species specificity with respect to egg factor-induced changes in sperm cyclic nucleotide metabolism.
mesh_terms: D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D006152:Cyclic GMP / Q000378:metabolism; D005260:Female; D005306:Fertilization; D006737:Horseshoe Crabs / Q000502:physiology; D008297:Male; D010063:Ovum / Q000502:physiology*; D012617:Sea Urchins; D013045:Species Specificity; D013081:Sperm Motility / Q000187:drug effects; D013084:Sperm-Ovum Interactions; D013094:Spermatozoa / Q000378:metabolism*; D013215:Starfish / Q000502:physiology; D013806:Theophylline / Q000494:pharmacology
chemical_list: D013806:Theophylline; D000242:Cyclic AMP; D006152:Cyclic GMP