title: [Clinical and biological alarm signs of drug allergy (author's transl)].
abstract: Allergic symptoms to medications, which cause treatment to be interrupted in order to prevent more serious accidents such as anaphylactic shock, are reviewed and their practical importance discussed. They are of small significance if functional as they can be produced by placebos, but are more disturbing if cutaneous and due to various non-specific and sometimes vague immuno-allergic mechanisms. Isolated fever of the allergic type has to be interpreted within the framework of the affection being treated. Raised blood eosinophil levels are a valid sign of an allergic antibody-type reaction. The value of detailed observation of symptoms and signs in such cases is demonstrated.
mesh_terms: D000917:Antibody Formation; D003875:Drug Eruptions; D004342:Drug Hypersensitivity / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D004804:Eosinophils / Q000032:analysis; D005334:Fever / Q000209:etiology; D006801:Humans
vernacular_title: Signes d'alarme cliniques et biologiques de l'allergie médicamenteuse.