Malignant fibrous histiocytoma of the larynx.
Fibrous histiocytoma is a rare mesenchymal tumor. The origin is believed to be a pleuri-potential cell, histiocytic in type, which can evolve into a facultative fibroblast under certain conditions. A case of a malignant fibrous histiocytoma in the subglottic larynx is reported. At present, the clinical behavior and degree of malignancy cannot be predicted. It appears that wide, local excision of the tumor with a margin of normal tissue is the treatment of choice. Regional block dissection of lymph nodes is not indicated unless clinically palpable nodes are present.
D000328:Adult; D005260:Female; D005931:Glottis / Q000601:surgery; D018219:Histiocytoma, Benign Fibrous / Q000601:surgery*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery*; D008197:Lymph Node Excision / Q000379:methods; D016038:Skin Transplantation; D014182:Transplantation, Autologous