Labetalol binding to specific alpha- and beta-adrenergic sites in vitro and its antagonism of adrenergic responses in vivo.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004082:Dihydroalprenolol / Q000037:antagonists & inhibitors; D004088:Dihydroergotoxine / Q000037:antagonists & inhibitors; D004285:Dogs; D004983:Ethanolamines / Q000494:pharmacology*; D005260:Female; D006168:Guinea Pigs; D006339:Heart Rate / Q000187:drug effects; D007741:Labetalol / Q000494:pharmacology*; D011817:Rabbits; D011869:Radioligand Assay; D011941:Receptors, Adrenergic / Q000187:drug effects*; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects*
D004983:Ethanolamines; D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D004088:Dihydroergotoxine; D004082:Dihydroalprenolol; D007741:Labetalol