[Oxidation of 4-anilino-5-methoxydioxybenzene-1,2 in complex biochemical systems possessing superoxide dismutase activity].
The kinetics of 4-anilino-5-methoxydioxybenzene-1,2 (AMOBQH2) autoxidation in biochemical systems possessing the superoxide dismutase activity were studied. The autoxidation of AMOBQH2 is affected by superoxide dismutase, which is indicative of participation of the superoxide radical in this process. The main kinetic effect of superoxide dismutase consists in a decrease of the effective rate constant for AMOBQH2 autoxidation. Peroxidase releases the superoxide dismutase inhibition of AMOBQH2 autoxidation. The data obtained are discussed in terms of a biochemical mechanism of action of biologically active aminoaromatic derivatives of o-benzoquinone.
D000818:Animals; D007700:Kinetics; D010084:Oxidation-Reduction; D011809:Quinones; D051381:Rats; D013482:Superoxide Dismutase / Q000378:metabolism*; D013481:Superoxides
D011809:Quinones; D013481:Superoxides; D013482:Superoxide Dismutase
Okislenie 4-anilino-5-metoksi-1,2-dioksibenzola v slozhnykh biokhimicheskikh sistemakh, obladaiushchikh superoksiddismutaznoĭ aktivnost'iu.