[T-lymphocyte diseases. Physiopathological and nosologic concepts (excluding cancer and graft rejection)].
The T-lymphocyte is at the heart of the physiopathological mechanism of most dysimmunity affections. Furthermore, some cases of granulomatosis, the immediate consequence of macrophagic disorder, come within the framework of T-lymphocyte diseases, épicritical centre of the complex process of cellular immunity. By reference to new knowledges about various actions of T-lymphocytes and their interactions with lymphocytes B and macrophages, and by reference to classic pathologic findings of diseases of immunity, the author's propose a new classification of these diseases, suggesting therapeutic reasearch in consideration of effect of drugs, especially immunostimulant treatments, on the immune system.
D000917:Antibody Formation; D001327:Autoimmune Diseases / Q000145:classification*; D001402:B-Lymphocytes / Q000502:physiology; D006801:Humans; D006968:Hypersensitivity, Delayed; D007105:Immune Complex Diseases / Q000145:classification*; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000145:classification*; D008264:Macrophages / Q000276:immunology; D010587:Phagocytosis; D013601:T-Lymphocytes / Q000276:immunology*
Les maladies du lymphocyte T. Conceptions physio-pathologiques et nosologiques (en dehors du cancer et du rejet de greffe).