Some comments on the article: 'The Structure of Human-Plasma Low-Density Lipoprotein B. An X-Ray Small-Angle Scattering Study' by K. Muller, P. Laggner, O. Glatter, and G. Kostner [Eur. J. Biochem. 82, 73--90 (1978)].
In their paper, K. Muller, P. Laggner, O. Glatter and G. Kostner report X-ray scattering and density experiments on human plasma low-density lipoprotein B, performed at different solvent densities (i.e. contrast variation method). The interpretation of the experimental data lead those authors to question the use of that method and particularly the use of the characteristic scattering functions in the study of serum lipoproteins. In the present paper it is shown that several aspects of their analysis are in fact highly questionable and that the objections raised are therefore unfounded.
D055598:Chemical Phenomena; D002621:Chemistry; D002627:Chemistry, Physical; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood; D008956:Models, Chemical; D008970:Molecular Weight; D011487:Protein Conformation; D011789:Quantum Theory; D014961:X-Ray Diffraction
D008077:Lipoproteins, LDL