[The effect of estrogens in the etiopathogenesis of endometrial adenocarcinoma].
Recent data suggesting that oestrogens also encourage the onset of adenocarcinoma of the endometrium in man are reviewed. Emphasis is placed on the fact that this is most likely to occur when prolonged oestrogeni stimulation is not suitably opposed by progesterone. It is felt that the latter, or its synthetic homologues, should be employed in all long-standing cases of exogenous or endogenous hyperoestrogenism.
D000230:Adenocarcinoma / Q000209:etiology*; D000328:Adult; D000818:Animals; D001943:Breast Neoplasms / Q000209:etiology; D002869:Chromosome Aberrations; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects; D004967:Estrogens / Q000009:adverse effects* / Q000378:metabolism; D005260:Female; D006801:Humans; D007564:Japan; D008593:Menopause; D051379:Mice; D009765:Obesity / Q000150:complications; D010051:Ovarian Neoplasms / Q000378:metabolism; D010298:Parity; D011374:Progesterone / Q000502:physiology; D011817:Rabbits; D051381:Rats; D011956:Receptors, Cell Surface; D012042:Registries; D012306:Risk; D014481:United States; D014594:Uterine Neoplasms / Q000209:etiology*
D003278:Contraceptives, Oral, Hormonal; D004967:Estrogens; D011956:Receptors, Cell Surface; D011374:Progesterone
L'azione degli estrogeni nell'eziopatogenesi dell'adenocarcinoma dell'endometrio.