[Antimalaria fluorescent antibodies evolution in young children living in a stable malaria area (author's transl)].
The detection of malarial fluorescent antibodies have been performed in an Abidjan dispensary on 30 newborn babies with their mothers, 30 children 3 months old and 120 children from 6 to 24 months. This survey took place during the small rainy season and it demonstrates that: --synthesis of specific antibodies is significantly starting after the 3rd month; --the rise, after six months, of the malarial antibodies is parallel to the plasmodic index checked during the same period in the same area; --the rate of antibodies in 2 years old babies is almost the same that in adults; --living conditions in rural areas accelerate the synthesis of antibodies which, adversely, is slowed down by regular chemoprophylaxis; --Plasmodium berghei is a valuable antigen for mass survey; --Abidjan town is an hypoendemic zone of stable malaria in a mesoendemic area.
D000917:Antibody Formation; D002675:Child, Preschool; D007560:Cote d'Ivoire; D005455:Fluorescent Antibody Technique; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008288:Malaria / Q000276:immunology*; D010962:Plasmodium berghei / Q000276:immunology
Evolution des anticorps fluorescents anti-palustres chez de jeunes enfants vivant en zone de paludisme stable.