The role of cytolysin in pneumococcal ocular infection.
A highly purified preparation of pneumococcal cytolysin was responsible for the corneal damage that ensued upon intra-corneal injection of crude cell extract into the rabbit eye. The lysin may produce this pathologic finding by effecting activation or release of corneal degradative enzymes.
D000818:Animals; D003316:Corneal Diseases / Q000139:chemically induced* / Q000201:enzymology; D004789:Enzyme Activation; D004790:Enzyme Induction; D006460:Hemolysin Proteins / Q000302:isolation & purification; D011008:Pneumococcal Infections / Q000201:enzymology / Q000209:etiology; D011817:Rabbits; D013296:Streptococcus pneumoniae
D006460:Hemolysin Proteins