title: [Synthesis of 2,3-diazaphenothiazine. IX. Derivatives of 1- and 4-alkylamine, triazole and N-10-dialkylaminoalky 2,3-diazaphenothiazine].
abstract: Methods of synthesis are described for 10H-pyridazino[4,5-b] [1,4]benzothiazine with alkylamine groups at the 1 and 4 position, triazole derivatives of the same heterocycle containing a pentadecanoic chain and derivatives with dialkylaminoalkyl groups at N-10. The results of pharmacological and microbiological examination are reported.
mesh_terms: D000588:Amines / Q000138:chemical synthesis; D000889:Anti-Arrhythmia Agents / Q000138:chemical synthesis; D003500:Cyclization; D004353:Drug Evaluation, Preclinical; D006634:Histamine H1 Antagonists / Q000138:chemical synthesis; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D010640:Phenothiazines / Q000138:chemical synthesis* / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014230:Triazoles / Q000138:chemical synthesis
chemical_list: D000588:Amines; D000889:Anti-Arrhythmia Agents; D006634:Histamine H1 Antagonists; D007202:Indicators and Reagents; D010640:Phenothiazines; D014230:Triazoles
vernacular_title: Sintesi di 2,3-diazafenotiazine. Nota IX - Derivati 1- e 4-alchilaminici, triazolici ed N-10-dialchilamino-alchilici della 2,3-diazafenotiazina