Lymphomatoid granulomatosis of the skin. A new clinocopathologic entity.
Lymphomatoid granulomatosis is a necrotizing arteritis primarily affecting the lungs but also found in the skin, kidneys, central nervous system, and other extra-pulmonary sites. Cutaneous involvement occurred in 45% of the cases described by Liebow in his original series. Light microscopy studies were performed. The IgA and IgG levels were slightly decreased and the IgE level was elevated. Cell-mediated immunity was impaired. No viruses were isolated or identified by immunofluorescence. A man had cutaneous lesions as the first sign of lymphomatoid granulomatosis.
D000368:Aged; D000818:Animals; D000956:Antigens, Viral; D001706:Biopsy; D002294:Carcinoma, Squamous Cell; D002417:Cattle; D002460:Cell Line; D005455:Fluorescent Antibody Technique; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000196:embryology; D007822:Laryngeal Neoplasms; D008168:Lung / Q000196:embryology; D008253:Macaca mulatta; D008297:Male; D010488:Polyarteritis Nodosa / Q000382:microbiology / Q000473:pathology; D012871:Skin Diseases / Q000382:microbiology / Q000473:pathology; D012883:Skin Ulcer / Q000473:pathology
D000956:Antigens, Viral