title: Diagnostic aspects of the cytomegalovirus mononucleosis syndrome in previously healthy persons.
abstract: The mononucleosis-like syndrome due to cytomegalovirus (CMV) has many clinical features in common with classic Epstein-Barr virus (EBV) induced infectious mononucleosis (IM). The hematologic and hepatic findings in both diseases are identical. Diagnosis of the CMV-IM syndrome usually can be made on the basis of indirect immunofluorescence for CMV macroglobulins (CMV-IgM). EBV virologic tests may also be necessary, as patients with primary EBV infections may have cross-reactions at low titer in the CMV-IgM test.
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D001219:Aspartate Aminotransferases / Q000097:blood; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D003937:Diagnosis, Differential; D005455:Fluorescent Antibody Technique; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007244:Infectious Mononucleosis / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D008099:Liver / Q000201:enzymology; D008297:Male; D013577:Syndrome
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D001219:Aspartate Aminotransferases