title: [Acute tuberculous meningitis in children. A report on 4 cases (author's transl)].
abstract: Four children were treated for acute tuberculous meningitis. One child died and 2 others were left with severe neurological sequellae. The diagnostic and clinical signs of tuberculous meningitis are reviewed. Treatment includes the administration of an association of INH-rifampicine and ethambutol orally, or INH-ethambutol-ethionamide intravenously when oral administration is impossible. Intrathecal injections of rifamycine SV can be given for acute forms. Corticoids have only one indication: intracranial hypertension with cerebral edema, which requires surgical decompression if no improvement is obtained. The fact that cases of tuberculous meningitis are still notified, is a justification for early BCG vaccination and regular control of the tuberculin allergic reaction.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D002675:Child, Preschool; D003422:Critical Care; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000627:therapeutic use; D005000:Ethionamide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D007427:Intracranial Pressure; D007538:Isoniazid / Q000627:therapeutic use; D008297:Male; D012293:Rifampin / Q000627:therapeutic use; D014390:Tuberculosis, Meningeal / Q000175:diagnosis / Q000517:prevention & control / Q000601:surgery / Q000628:therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D004977:Ethambutol; D005000:Ethionamide; D007538:Isoniazid; D012293:Rifampin
vernacular_title: Méningite tuberculeuse grave de l'enfant. A propos de quatre observations dans un service de réanimation.