[Contribution of immunoglobulin assays to the diagnosis of human African trypanosomiasis in patients immunologically suspect (immunofluorescence and ELISA). A preliminary report (author's transl)].
Can the diagnosis of sleeping sickness in patients immunologically suspect, without seeing the parasite, be obtained by dosing IgG and IgM? The authors demonstrate that two groups of people with positive immunodiagnosis, one parasitologically confirmed and the other not confirmed, do not show significant difference when dosing immunoglobulins. These two groups respectively show a significant difference when compared with a parasitologically and immunologicaly negative group. The simultaneous increase in IgG and IgM might confirm the immunodiagnosis.
D007560:Cote d'Ivoire; D005455:Fluorescent Antibody Technique; D006801:Humans; D007124:Immunoenzyme Techniques; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D008403:Mass Screening / Q000379:methods; D014353:Trypanosomiasis, African / Q000175:diagnosis* / Q000453:epidemiology
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Apport du dosage des immunoglobulines pour de diagnostic de la trypanosomiase humaine africaine chez les suspects immunologiques (immunofluorescence et ELISA). Résultats préliminaires.