[Proliferation of hamster embryo fibroblast cultures infected with the herpes simplex virus].
In the HEF system in logarythmic and stationary phases of the culture growth the type-2 herpes simplex virus serves as a stimulator of proliferative processes in the cell (there is an increase of the labelled cells index, mitotic index and the intensity of labelling). The capacity of herpes virus not to suppress the cell DNA synthesis, as infestious viruses do, but to stimulate poliferative abilities of the cell indicates a presumable potential oncogenicity of this virus.
D000818:Animals; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured; D006224:Cricetinae; D003588:Cytopathogenic Effect, Viral; D004247:DNA / Q000096:biosynthesis; D005347:Fibroblasts / Q000382:microbiology*; D008940:Mitotic Index; D009858:Oncogenic Viruses; D018139:Simplexvirus / Q000472:pathogenicity*; D013997:Time Factors
D004247:DNA
Proliferatsiia kul'tur fibroblastov émbrionov khomiaka, zarazhennykh virusom prostogo gerpesa.