A different genetic code in human mitochondria.
Comparison of the human mitochrondial DNA sequence of the cytochrome oxidase subunit II gene and the sequence of the corresponding beef heart protein shows that UGA is used as a tryptophan codon and not as a termination codon and suggests that AUA may be a methionine and not an isoleucine codon. The cytochrome oxidase II gene is contiguous at its 5' end with a tRNAAsp gene and there are only 25 bases at its 3' end before a tRNALys gene. These tRNA'S are different from all other known tRNA sequences.
D001224:Aspartic Acid / Q000235:genetics; D001483:Base Sequence; D003062:Codon; D004272:DNA, Mitochondrial / Q000235:genetics*; D003576:Electron Transport Complex IV / Q000235:genetics*; D005796:Genes; D005815:Genetic Code; D006801:Humans; D007532:Isoleucine / Q000235:genetics; D008239:Lysine / Q000235:genetics; D008715:Methionine / Q000235:genetics; D012343:RNA, Transfer / Q000235:genetics; D014364:Tryptophan / Q000235:genetics
D003062:Codon; D004272:DNA, Mitochondrial; D007532:Isoleucine; D001224:Aspartic Acid; D014364:Tryptophan; D012343:RNA, Transfer; D008715:Methionine; D003576:Electron Transport Complex IV; D008239:Lysine