Effect of L-histidine on the survival of a T-strain of mycoplasma.
The addition of L-histidine to the growth medium prolongs the stationary phase and the survival of a T-strain of mycoplasma. Results of an experiment performed with (14)C-labeled urea demonstrate that the action of L-histidine is based on the retardation of the rise of pH.
D002021:Buffers; D002250:Carbon Radioisotopes; D002452:Cell Count; D002470:Cell Survival / Q000187:drug effects; D006639:Histidine / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D009174:Mycoplasma / Q000254:growth & development* / Q000378:metabolism; D010879:Piperazines; D013237:Stereoisomerism; D013451:Sulfonic Acids; D014508:Urea / Q000378:metabolism
D002021:Buffers; D002250:Carbon Radioisotopes; D010879:Piperazines; D013451:Sulfonic Acids; D006639:Histidine; D014508:Urea