Marek's disease in chickens: correlation of Marek's disease with nuclear-inclusion formation in feather-follicle epithelium.
The dynamics of nuclear-inclusion (NI) formation in feather-follicle epithelium of chickens inoculated with Marek's disease virus (with or without prior immunization with turkey herpesvirus) could be divided into two patterns: 1) transient NI formation at the initial stage postchallenge; and 2) persistent NI formation. Incidence of Marek's disease was closely correlated with the dynamics of NI formation. Active NI formation recurred in chickens showing pattern 2 and was closely related to the incidence of nerve lesions.
D000818:Animals; D002645:Chickens / Q000382:microbiology*; D004848:Epithelium / Q000382:microbiology; D005241:Feathers / Q000382:microbiology*; D006564:Herpesviridae / Q000276:immunology; D008381:Herpesvirus 2, Gallid / Q000254:growth & development*; D007114:Immunization / Q000662:veterinary; D007181:Inclusion Bodies, Viral; D008380:Marek Disease / Q000382:microbiology* / Q000473:pathology / Q000517:prevention & control; D014422:Turkeys