title: Occurrence of infection with group B coxsackievirus in rheumatic and nonrheumatic Filipino children.
abstract: The pathogenesis of rheumatic fever has been linked to various immune mechanisms involving streptococcal antibodies and heart tissue antigens. Latent myocarditis due to group B coxsackievirus has also been considered as a possible conditioning factor. The validity of the role of infection with group B coxsackievirus in rheumatic fever was tested by determining the incidence of type-specific neutralizing antibodies in sera of Filipino children. Analysis of the results by means of a normal Z-test showed that the incidence in rheumatic children was not statistically significant in comparison to the incidence in asymptomatic children.
mesh_terms: D000293:Adolescent; D000914:Antibodies, Viral / Q000032:analysis*; D002648:Child; D003384:Coxsackievirus Infections / Q000150:complications*; D029822:Enterovirus B, Human / Q000276:immunology*; D006801:Humans; D009500:Neutralization Tests; D010679:Philippines; D012213:Rheumatic Fever / Q000150:complications* / Q000276:immunology
chemical_list: D000914:Antibodies, Viral