title: [Pathogenetic therapy of nervous system and muscular diseases using large doses of prednisolone on alternate days].
abstract: A total of 230 patients with myasthenia, polymositis, disseminated sclerosis and myeloradiculopolyneuronitis were administered high doses of prednisolone (up to 100 mg) every other day. The treatment efficacy and low incidence of side effects and complications are emphasized. High doses of prednisolone given every other day do not inhibit secretions of endogenic ACTH and cortisol. The immunodepressant effect of the drug remains unchanged.
mesh_terms: D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D003345:Corticosterone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008722:Methods; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy; D009135:Muscular Diseases / Q000188:drug therapy*; D009187:Myelitis / Q000188:drug therapy; D009220:Myositis / Q000188:drug therapy; D009422:Nervous System Diseases / Q000188:drug therapy*; D011129:Polyradiculoneuropathy / Q000188:drug therapy; D011239:Prednisolone / Q000008:administration & dosage*
chemical_list: D000324:Adrenocorticotropic Hormone; D011239:Prednisolone; D003345:Corticosterone; D006854:Hydrocortisone
vernacular_title: Patogeneticheskaia terapiia zabolevaniĭ nervnoĭ sistemy i myshts bol'shimi dozami prednizolona cherez den'.