Effects of insulin on plasma fibrinogen levels in rats submitted to tissue injury or ACTH administration.
Insulin is necessary to produce an increase of plasma fibrinogen in rats submitted to tissue injury or ACTH administration. This increase is more significant when endogenous or exogenous excess of insulin is present, while in uninjured rats the absence or excess insulin does not modify plasma fibrinogen.
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000097:blood; D005260:Female; D005340:Fibrinogen / Q000378:metabolism*; D007328:Insulin / Q000494:pharmacology*; D007813:Laparotomy; D008297:Male; D051381:Rats; D014044:Tolbutamide / Q000494:pharmacology; D014947:Wounds and Injuries / Q000097:blood*
D007328:Insulin; D005340:Fibrinogen; D000324:Adrenocorticotropic Hormone; D014044:Tolbutamide