Surgical treatment of tendosynovial sarcoma.
Tendosynovial sarcoma is notorious for its high rates of local recurrence and metastases after surgical treatment. A retrospective study was made of 109 cases of monobloc wide soft part resection and amputation for primary tumors, and 29 patients who underwent resection of pulmonary metastases. Actuarial five-year survival rates after soft part resection was 70% for untreated, and 61% for previously treated, locally recurrent neoplasms. Corresponding rates after amputation were 47% and 64%. Local tumor recurrence developed in 18% of the primary soft part resections and 4% of the amputations, usually when some basic surgical principle had been violated. 35% five-year survival was achieved with judicious resection of solitary and multiple lung metastases in most cases without chemotherapy. Local control of a tendosynovial sarcoma can be achieved with properly executed surgical procedures which adhere to established tenets of cancer surgery. Resection of pulmonary metastases merits an important position in the management of these patients.
D000671:Amputation, Surgical; D001132:Arm; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000601:surgery*; D008197:Lymph Node Excision; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D011013:Pneumonectomy; D013584:Sarcoma, Synovial / Q000401:mortality / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000401:mortality / Q000601:surgery*; D013848:Thigh