title: [Catecholamine sensitivity of the hypophyseal-adrenal system in the early ontogeny of rats].
abstract: The dynamics of the hypophyseal-suprarenal system reaction to catecholamines of different type of effect was studied in the Wistar rats during the first 16 days of life. The reaction to epinephrine was noted in 4 days old and to novodrin in 8 days old rats. Since the reaction to epinephrine acting on alpha- and beta-receptors appears ahead of that to novodrin acting selectively on beta-receptors, a suggestion was put forward to the effect that alpha-receptors matured more rapidly that beta-receptors. The increase of the system reaction to the stimulation of recepors sensitive to catecholamines was noted on the 12-14th days of life and appears to be related to the formation of central adrenergic mechanisms.
mesh_terms: D015062:11-Hydroxycorticosteroids / Q000097:blood; D000302:Adrenal Cortex / Q000187:drug effects; D000305:Adrenal Cortex Hormones / Q000097:blood; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D002395:Catecholamines / Q000494:pharmacology*; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D010913:Pituitary-Adrenal System / Q000187:drug effects*; D051381:Rats; D013997:Time Factors
chemical_list: D015062:11-Hydroxycorticosteroids; D000305:Adrenal Cortex Hormones; D002395:Catecholamines; D000324:Adrenocorticotropic Hormone; D007545:Isoproterenol; D004837:Epinephrine
vernacular_title: Chuvstvitel'nost' gipofizarno-nadpochechnikovoĭ sistemy k kateckholaminam v rannem ontogeneze krys.