[Effect of thymocytes on the quantity of polypotent hematopoietic mast cells in the spleen of sublethally irradiated mice].
With the aid of Till and McCulloch's method, 5 times 10(-6) thymic cells were found to cause an increase in the number of hemopoietic endogenous spleen colonies in syngeneic donor-recipient combination. Thymic cells of C57BL mice had no effect on the number of endogenous colonies in the spleen. 40 times 10(-6) thymic cells administered 24 hr after sublethal irradiation caused an increase in the number of colony forming units in the spleen within 14 days. Possible ways of the thymus effect on hemopoiesis are discussed.
D000818:Animals; D002452:Cell Count; D017690:Cell Transplantation; D003584:Cytological Techniques; D004307:Dose-Response Relationship, Radiation; D006412:Hematopoietic Stem Cells / Q000528:radiation effects*; D006824:Hybridization, Genetic; D008407:Mast Cells / Q000528:radiation effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011830:Radiation Effects; D013154:Spleen / Q000166:cytology* / Q000528:radiation effects; D013950:Thymus Gland / Q000166:cytology*; D013997:Time Factors
Vliianie kletok timusa na kolichestvo polipotentnykh stvolovykh krovetvornykh kletokv selezenke subletal'no obluchennykh mysheĭ