A human neoplastic hematopoietic cell line producing a fibroblast type of interferon.
1301 is a subline of the EBV-genome negative T leukemia line CCRF-CEM. IF was induced by Sendai virus. By use of neutralizing antisera and by studies of some physical properties it could be shown that IF was of the fibroblast type. This was confirmed by its antiviral effect on heterologous cell lines.
D000818:Animals; D002460:Cell Line; D005347:Fibroblasts; D006358:Hot Temperature; D006801:Humans; D007372:Interferons / Q000096:biosynthesis* / Q000276:immunology / Q000494:pharmacology; D007945:Leukemia, Lymphoid; D009500:Neutralization Tests; D010222:Parainfluenza Virus 1, Human
D007372:Interferons