[Nature of the hyperpotassic composition of the medium surrounding individual tissue mechanoreceptors].
The ouabain effect on potassium concentration in the Pacini corpuscle fluid was studied using continuous perfusion of cat's mesenteric receptors with ouabain in Ringer's bicarbonate solution. To check the solution penetration into the corpuscles, Na36Cl and (G-3H)-ouabain were used. 2 . 10(-2) mM ouabain reduced (K+) in corpuscle fluid. The high potassium concentration in Pacini corpuscle fluid seems to be due to Na+--K+-ATPase system.
D000818:Animals; D002415:Cats; D002463:Cell Membrane Permeability; D005110:Extracellular Space / Q000378:metabolism*; D008297:Male; D008465:Mechanoreceptors / Q000378:metabolism*; D008643:Mesentery / Q000294:innervation; D010042:Ouabain / Q000494:pharmacology; D010141:Pacinian Corpuscles / Q000187:drug effects / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism*; D012965:Sodium Chloride / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000502:physiology
D012965:Sodium Chloride; D010042:Ouabain; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium
O prirode giperkalievogo sostava sredy, okruzhaiushcheĭ odinochnye tkanevye mekhanoretseptory.