Pyrophosphate retention by previously irradiated renal tissue.
In 3 patients, each of whom had previously had part of one kidney included within the field during radiation therapy, whole-body bone imaging using 99mTc-pyrophosphate showed increased activity in the irradiated renal segment. Possible mechanisms of such renal uptake are discussed.
D000293:Adolescent; D000328:Adult; D001842:Bone and Bones / Q000000981:diagnostic imaging; D011756:Diphosphates / Q000378:metabolism*; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D011877:Radionuclide Imaging; D013667:Technetium / Q000378:metabolism*; D013899:Thoracic Neoplasms / Q000532:radiotherapy
D011756:Diphosphates; D013667:Technetium