Bisulfite induced lipid oxidation.
Bisulfite (0.5 to 10 millimolar) initiates oxidation of lipids in aqueous emulsions of corn oil in a dose-dependent manner as measured by reaction with thiobarbituric acid. The reaction is effectively quenched by the antioxidant, 2,6-dit-butyl-4-hydroxymethyl phenol as well as by Mn+2 (10(-5)-10(-3)M). The latter observation is in disagreement with that reported by others and suggests that in case of lipids an alternative mechanism exists for the initiation of reactive species.
D000975:Antioxidants / Q000494:pharmacology*; D002084:Butylated Hydroxytoluene / Q000031:analogs & derivatives / Q000494:pharmacology; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D006863:Hydrogen-Ion Concentration; D050356:Lipid Metabolism; D008345:Manganese / Q000494:pharmacology; D009821:Oils / Q000378:metabolism; D010084:Oxidation-Reduction; D013447:Sulfites / Q000494:pharmacology*
D000975:Antioxidants; D009821:Oils; D013447:Sulfites; D002084:Butylated Hydroxytoluene; D008345:Manganese