A fatal enteric syndrome in Mystromys albicaudatus (white tailed rat) following topical antibiotic treatment.
Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs. Clinical signs included anorexia, depression, and rough hair coat. Predominant necropsy findings were hrmorrhagic typhlitis and colitis. Results of studies evaluating the roles of the anesthetic and the tropical antibiotic ointment suggested that the deaths were caused by ingestion of the topically applied antibiotic.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D001414:Bacitracin / Q000009:adverse effects; D002429:Cecal Diseases / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary; D002432:Cecum / Q000473:pathology; D003092:Colitis / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary; D003106:Colon / Q000473:pathology; D007410:Intestinal Diseases / Q000662:veterinary*; D009355:Neomycin / Q000009:adverse effects; D011113:Polymyxins / Q000009:adverse effects; D051381:Rats; D012376:Rodent Diseases / Q000139:chemically induced* / Q000473:pathology
D000900:Anti-Bacterial Agents; D011113:Polymyxins; D001414:Bacitracin; D009355:Neomycin