title: Inactivation of E. coli RNA polymerase by pyridoxal 5'-phosphate: identificationof a low pKa lysine as the modified residue.
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D001665:Binding Sites; D001894:Borohydrides; D012321:DNA-Directed RNA Polymerases / Q000037:antagonists & inhibitors*; D004926:Escherichia coli / Q000187:drug effects; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008239:Lysine / Q000032:analysis; D011485:Protein Binding; D011487:Protein Conformation; D011732:Pyridoxal Phosphate / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D000596:Amino Acids; D001894:Borohydrides; D011732:Pyridoxal Phosphate; D012321:DNA-Directed RNA Polymerases; D008239:Lysine