Incorporation of HLA antigens into the envelope of RNA tumor viruses grown in human cells.
Virion antigens of feline leukemia virus are associated with HLA antigens in the membrane of human cells infected with the virus. Feline leukemia virus produced by these cells incorporates host membrane antigens into the virion envelope, making the virus susceptible to lysis by antisera directed to HLA or to uninfected cells plus complement.
D000818:Animals; D000954:Antigens, Surface / Q000032:analysis; D000956:Antigens, Viral; D002460:Cell Line; D002478:Cells, Cultured; D005455:Fluorescent Antibody Technique; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D005256:Leukemia Virus, Feline / Q000378:metabolism; D012190:Retroviridae / Q000276:immunology / Q000378:metabolism*; D014412:Tumor Virus Infections; D014779:Virus Replication
D000954:Antigens, Surface; D000956:Antigens, Viral; D006680:HLA Antigens