Lack of sequence homology between the nucleic acids of Rauscher leukaemia virus and polyoma virus Y8e produced simultaneously in a continuous mouse cell line.
In a continuous cell line (Y8e) from spleen and thymus cells of mice, infected with RLV, the presence of both RLV and polyoma virus Y8e in a single cell could be demonstrated by electron microscopy. A comparison of the nucleic acids of RLV and polyoma virus from Y8e cells by two molecular hybridization methods showed lack of sequence homology between the viral nucleic acids.
D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D002467:Cell Nucleus / Q000378:metabolism; D004279:DNA, Viral / Q000096:biosynthesis; D051379:Mice; D008854:Microscopy, Electron; D009693:Nucleic Acid Hybridization; D011120:Polyomavirus / Q000378:metabolism*; D012367:RNA, Viral / Q000096:biosynthesis; D011925:Rauscher Virus / Q000378:metabolism*; D013045:Species Specificity; D013154:Spleen; D013950:Thymus Gland
D004279:DNA, Viral; D012367:RNA, Viral