title: Irreversible protein binding of [14-C]imipramine with rat and human liver microsomes.
mesh_terms: D000818:Animals; D002248:Carbon Monoxide / Q000494:pharmacology; D002417:Cattle; D065607:Cytochrome P-450 Enzyme Inhibitors; D004851:Epoxide Hydrolases / Q000037:antagonists & inhibitors; D006801:Humans; D007099:Imipramine / Q000378:metabolism*; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism*; D009249:NADP / Q000494:pharmacology; D011335:Proadifen / Q000494:pharmacology; D011485:Protein Binding; D051381:Rats; D012293:Rifampin / Q000494:pharmacology; D012710:Serum Albumin, Bovine / Q000378:metabolism; D013438:Sulfhydryl Compounds / Q000494:pharmacology; D013997:Time Factors
chemical_list: D065607:Cytochrome P-450 Enzyme Inhibitors; D013438:Sulfhydryl Compounds; D012710:Serum Albumin, Bovine; D009249:NADP; D002248:Carbon Monoxide; D011335:Proadifen; D004851:Epoxide Hydrolases; D007099:Imipramine; D012293:Rifampin