Heterogeneity of A/Singapore/1/57 (H2N2) influenza virus.
The population of A/Singapore/1/57 (H2N2) influenza virus was found to contain two types of infectious particle. "Normal" virions with a diameter from 100-130 nm, a buoyant density in sucrose of 1.21 g/cm3 and a sedimentation coefficient 770 S represented about 90 percent of the population. In addition, a considerable amount of larger particles (up to 1000 nm) with a buoyant density in sucrose of 1.18 g/cm3 and a sedimentation coefficient of over 1000 S were present.
D002499:Centrifugation, Density Gradient; D002501:Centrifugation, Zonal; D053121:Influenza A Virus, H2N2 Subtype; D009980:Influenza A virus / Q000032:analysis* / Q000648:ultrastructure; D009975:Orthomyxoviridae / Q000032:analysis*