title: Vaccination against diseases associated with herpesvirus infections in animals: a review.
abstract: An account is presented of the development and use of herpesvirus vaccines in domestic animals, with particular reference to those viruses causing cytolytic rather than oncogenic infections. The chief infections covered are Aujeszky's disease (AD or pseudorabies), infectious bovine rhinotracheitis (IBR) and equine rhinopneumonitis (equine abortion; EHV-1). Others mentioned are feline viral rhinotracheitis and malignant catarrhal fever of cattle. Both live-modified and inactivated vaccines are widely used or under development for ADV, IBR and EHV-1. Live vaccines are generally regarded as successful in some circumstances but have major drawbacks, both in regard to safety or immunogenicity for the individual animal or to efforts to control and eliminate the viruses from whole populations. Difficulties remian in the preparation and use of inactivated vaccines, which still suffer from many of the epidemiological objections raised against modified live vaccines.
mesh_terms: D000818:Animals; D002415:Cats; D002417:Cattle; D002645:Chickens; D005260:Female; D006564:Herpesviridae / Q000276:immunology*; D006566:Herpesviridae Infections / Q000517:prevention & control / Q000662:veterinary*; D004861:Herpesvirus 1, Equid / Q000276:immunology; D006736:Horses; D007241:Infectious Bovine Rhinotracheitis / Q000517:prevention & control; D008380:Marek Disease / Q000517:prevention & control; D011247:Pregnancy; D011557:Pseudorabies / Q000517:prevention & control; D013552:Swine; D014765:Viral Vaccines / Q000302:isolation & purification / Q000627:therapeutic use*
chemical_list: D014765:Viral Vaccines