Effect of exogenous interferon on neonatal infection with murine cytomegalovirus.
One dose of interferon given before inoculation of MCMV to the neonatal mouse resulted in less virus in the submaxillary glands and reduced tissue damage due to MCMV infection, probably by modulating the immune system.
D000818:Animals; D000831:Animals, Newborn; D003587:Cytomegalovirus / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control*; D007109:Immunity / Q000187:drug effects; D066298:In Vitro Techniques; D007372:Interferons / Q000494:pharmacology*; D008213:Lymphocyte Activation; D051379:Mice; D013363:Submandibular Gland / Q000382:microbiology
D007372:Interferons