Inhibition of adenosine 3',5'-monophosphate-dependent protein kinase by staphylococcal alpha-toxin.
Staphylococcal alpha-toxin inhibited the activity of cyclic adenosine 3',5'-monophosphate-dependent protein kinase by competitive inhibition, probably by its interaction with a cyclic adenosine 3',5'-monophosphate-binding site in the protein kinase molecule.
D001427:Bacterial Toxins / Q000494:pharmacology*; D001665:Binding Sites; D001667:Binding, Competitive; D000242:Cyclic AMP / Q000378:metabolism; D011485:Protein Binding; D047428:Protein Kinase Inhibitors; D013210:Staphylococcus
D001427:Bacterial Toxins; D047428:Protein Kinase Inhibitors; D000242:Cyclic AMP