Cell-mediated immunity, Epstein-Barr virus and nasopharyngeal carcinoma.
Cellular immunity is apparently important in host defenses against cancer. A growing body of information on CMI to EBV is here reviewed, providing a strong basis for studies of such reactivity in NPC. Present work suggests that CMI responses to virus- and tumour-associated antigens may have implications for etiology, diagnosis and treatment.
D000818:Animals; D000956:Antigens, Viral; D002277:Carcinoma / Q000276:immunology*; D002455:Cell Division; D006564:Herpesviridae / Q000276:immunology; D006566:Herpesviridae Infections / Q000276:immunology; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000276:immunology; D007244:Infectious Mononucleosis / Q000276:immunology; D007957:Leukocyte Adherence Inhibition Test; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000378:metabolism; D008222:Lymphokines / Q000096:biosynthesis; D008233:Lymphotoxin-alpha / Q000096:biosynthesis; D009303:Nasopharyngeal Neoplasms / Q000276:immunology*; D010835:Phytohemagglutinins / Q000494:pharmacology; D012882:Skin Tests; D013601:T-Lymphocytes / Q000276:immunology; D014412:Tumor Virus Infections / Q000276:immunology
D000956:Antigens, Viral; D008222:Lymphokines; D008233:Lymphotoxin-alpha; D010835:Phytohemagglutinins