Ribosome lamella complex in neoplastic cells of a Sézary's syndrome.
The first case of ribosome lamella complex (RLC) is reported in abnormal cells of a Sézary's syndrome, a T cell malignancy. Until now this ultrastructural cytoplasmic inclusion has usually been described in hairy cell leukaemia and other lymphoproliferative syndromes of B cell origin. Since RLC are also observed in abnormal lymphoid T cells, in non lymphoid cells, and moreover in non haematopoietic cells, they lack diagnostic specificity.
D000368:Aged; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D012270:Ribosomes / Q000648:ultrastructure*; D012751:Sezary Syndrome / Q000097:blood*; D013601:T-Lymphocytes / Q000648:ultrastructure*