[Adrenergic regulation of thermogenesis in Siberian lemmings].
Siberian lemmings seem to have lesser noradrenaline (NA) calorigenic action and higher beta-adrenergic "asymmetry" of catecholamine calorigenic effects than the cold- and warmth-adapted laboratory rodents. Selective inhibition of catecholamine effects by beta-adrenoblocking drug propranolol, obvious potentiation of NA effect by caffeine, and compensatory increasing of thermoregulatory musclar contractile activity during the blockade of betaadrenoreceptors under cooling suggest the domineering of betaadrenergic mechanisms of thermogenesis in siberian lemmings and their high thermoregulatory lability.
D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D001833:Body Temperature Regulation / Q000187:drug effects; D002110:Caffeine / Q000494:pharmacology; D004347:Drug Interactions; D007545:Isoproterenol / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects; D011433:Propranolol / Q000494:pharmacology; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000502:physiology; D012377:Rodentia / Q000502:physiology*; D013564:Sympathetic Nervous System / Q000502:physiology*
D011943:Receptors, Adrenergic, beta; D002110:Caffeine; D011433:Propranolol; D007545:Isoproterenol; D009638:Norepinephrine
Osobennosti adrenergicheskoĭ reguliatsii termogeneza u sibirskikh lemmingov.