title: Endogenous opiates: through 1978.
abstract: The discovery of receptors in the brain for opiates and the structure of the endogenous peptides for these receptors has led to an explosion of interest in this field. The present review is the first of an annual series. It summarizes many of the highlights of research with opiate peptides published with a date of 1978 or earlier.
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D001931:Brain Mapping; D004361:Drug Tolerance; D004569:Electroencephalography; D004723:Endorphins / Q000378:metabolism* / Q000494:pharmacology; D004745:Enkephalins / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D007858:Learning / Q000187:drug effects; D001523:Mental Disorders / Q000188:drug therapy; D011939:Mental Recall / Q000187:drug effects; D009020:Morphine / Q000494:pharmacology; D009270:Naloxone / Q000494:pharmacology; D009619:Nociceptors / Q000187:drug effects; D011957:Receptors, Opioid / Q000378:metabolism; D009435:Synaptic Transmission / Q000187:drug effects
chemical_list: D004723:Endorphins; D004745:Enkephalins; D011957:Receptors, Opioid; D009270:Naloxone; D009020:Morphine