Is prolactin involved in sperm capacitation?
Immunoreactive prolactin in high concentration was detected in the human semen. Therefore, the effect of prolactin on the various metabolic parameters of the human spermatozoa was studied. It was found that prolactin brought about many of the biochemical changes in the spermatozoa which are known to be associated with the process of capacitation. These results suggest that prolactin has a role in the sperm capacitation.
D000177:Acrosome / Q000187:drug effects; D000251:Adenosine Triphosphatases / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D002463:Cell Membrane Permeability / Q000187:drug effects; D000242:Cyclic AMP / Q000378:metabolism; D004789:Enzyme Activation; D005307:Fertilization in Vitro / Q000187:drug effects; D005632:Fructose / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008297:Male; D011388:Prolactin / Q000032:analysis / Q000494:pharmacology* / Q000502:physiology; D012661:Semen / Q000032:analysis; D013075:Sperm Capacitation / Q000187:drug effects*; D013094:Spermatozoa / Q000187:drug effects / Q000378:metabolism; D013752:Tetracycline / Q000378:metabolism
D005632:Fructose; D011388:Prolactin; D000242:Cyclic AMP; D000251:Adenosine Triphosphatases; D013752:Tetracycline; D005947:Glucose; D002118:Calcium