title: An infectious bursal disease virus outbreak in 14- and 15-week-old chickens.
abstract: Infectious bursal disease virus (IBDV) observed in a flock of 14- and 15-week-old chickens was typical of the acute symptomatic IBDV infections more common in younger birds. High flock morbidity was indicated by a marked decrease in feed consumption, although deaths were not excessive. At necropsy, affected birds had small hemorrhages in thigh muscles, creamy-yellow-colored bursae of Fabricius with prominent longitudinal striations, and swollen mottled kidneys. Histopathologic examination revealed bursal lesions typical of IBDV infection. One of six sera from necropsied birds was positive for antibody to IBDV in the agar-gel precipitin (AGP) test, and one week later all 35 samples tested were positive. Bursae were homogenized and found to contain IBDV as evidenced by precipitation, with antibody to IBDV, in the AGP test.
mesh_terms: D000367:Age Factors; D000818:Animals; D002060:Bursa of Fabricius / Q000382:microbiology / Q000473:pathology; D002645:Chickens; D004196:Disease Outbreaks / Q000662:veterinary*; D007243:Infectious bursal disease virus / Q000302:isolation & purification; D011201:Poultry Diseases / Q000382:microbiology; D012087:Reoviridae / Q000302:isolation & purification; D012088:Reoviridae Infections / Q000662:veterinary*