Effects of lithium chloride on peripheral acetylcholine release and brain acetylcholine levels in the guinea-pig.
Lithium chloride administered acutely or chronically to guinea-pigs had no effect on brain level of acetylcholine or on peripheral release of acetylcholine from longitudinal muscle of the ileum. The results suggest differences between in vitro and in vivo action of lithium.
D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005071:Evoked Potentials; D006168:Guinea Pigs; D008094:Lithium / Q000494:pharmacology*; D009469:Neuromuscular Junction / Q000187:drug effects* / Q000378:metabolism; D010525:Peripheral Nerves / Q000187:drug effects; D009435:Synaptic Transmission / Q000187:drug effects
D008094:Lithium; D000109:Acetylcholine