title: Puncture wounds of the foot.
abstract: Serious complications occurred in 29 of 887 children with puncture wounds of the feet treated over a four-year period at the Dr. Charles A. Janeway Child Health Centre. Osteomyelitis in one of the small bones of the foot was the commonest complication and occurred when a cartilaginous surface (physeal plate or articular cartilage) had been violated. Although systemic signs of osteomyelitis frequently are absent, this infectious process is refractory to medical management. The combined surgical and medical management of this complication is outlined. Management of puncture wounds in the emergency room should include a thorough history concisely recorded, tetanus prophylaxis, and cleansing, debridement, and probing of the wound. Antimicrobial agents are not routinely required but should be reserved for patients presenting late with cellulitis or an established infection. A semisynthetic penicillinase-penicillin appears to be the agent of choice until the results of microbiologic studies are available.
mesh_terms: D000293:Adolescent; D002481:Cellulitis / Q000209:etiology / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D003091:Colistin / Q000627:therapeutic use; D004917:Erythromycin / Q000627:therapeutic use; D005260:Female; D018409:Foot Injuries; D006801:Humans; D007710:Klebsiella Infections / Q000628:therapy; D008034:Lincomycin / Q000627:therapeutic use; D008297:Male; D010019:Osteomyelitis / Q000209:etiology; D010406:Penicillins / Q000627:therapeutic use; D011552:Pseudomonas Infections / Q000628:therapy; D013203:Staphylococcal Infections / Q000628:therapy; D013290:Streptococcal Infections / Q000628:therapy; D013754:Tetracyclines / Q000627:therapeutic use; D014950:Wounds, Penetrating / Q000150:complications / Q000628:therapy
chemical_list: D010406:Penicillins; D013754:Tetracyclines; D004917:Erythromycin; D008034:Lincomycin; D003091:Colistin