Heterogeneity of human plasma low density lipoprotein.
Low density lipoprotein (LDL) was fractionated into subspecies by the use of DEAE-agarose column chromatography and the peptide compositions of the LDL subspecies which eluted at different NaCl concentrations were determined. LDL which elutes at low NaCl concentration has relatively less non-B apoprotein than does LDL which elutes at high salt concentration. The LDL subspecies which elute at high NaCl concentration contain more apo A-1 than do those which elute at the lower NaCl molarity. These results indicate that LDL consists of subfractions which differ in their peptide compositions.
D002852:Chromatography, Ion Exchange; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood*; D009994:Osmolar Concentration; D011506:Proteins / Q000032:analysis; D012965:Sodium Chloride
D008077:Lipoproteins, LDL; D011506:Proteins; D012965:Sodium Chloride