Isolation and characterization of the transferrin receptor from human placenta.
The transferrin receptor has been isolated from human placenta using immunochromatography and affinity chromatography. The receptor is a glycoprotein and has a Mr = 90,000 on sodium dodecyl sulfate-gel electrophoresis in the presence of 2-mercaptoethanol. The isolated receptor is immunologically related to the transferrin receptor on the reticulocyte cell surface.
D000596:Amino Acids / Q000032:analysis; D002241:Carbohydrates / Q000032:analysis; D002462:Cell Membrane / Q000378:metabolism; D005260:Female; D006023:Glycoproteins / Q000302:isolation & purification / Q000378:metabolism; D006801:Humans; D005779:Immunodiffusion; D008970:Molecular Weight; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D011956:Receptors, Cell Surface / Q000302:isolation & purification* / Q000378:metabolism; D012156:Reticulocytes / Q000378:metabolism; D014168:Transferrin / Q000378:metabolism*
D000596:Amino Acids; D002241:Carbohydrates; D006023:Glycoproteins; D011956:Receptors, Cell Surface; D014168:Transferrin