[Immunocytologic analysis, in rat hypothalamus, of neurons producing peptides related to endorphin, ACTH, MSH and beta-LPH. Comparison with other peptidergic and monoaminergic neurons].
In rat hypothalamus intraventricularly injected with colchicine, the same neurons of the ventral region are stained with I.S. against alpha and beta-endorphin, (1-24) and (17-39) ACTH, alpha and beta-MSH, and beta-LPH. They are distinct from those producing LH-RH, somatostatin, neurophysin, and dopamine. These results suggest that the same neurons elaborate peptides identical with or immunologically related to endorphins, ACTH, alpha-MSH and beta-LPH, probably issued from a common precursor.
D000324:Adrenocorticotropic Hormone / Q000032:analysis*; D000818:Animals; D001679:Biogenic Amines / Q000032:analysis; D004298:Dopamine / Q000032:analysis; D004723:Endorphins / Q000032:analysis*; D006651:Histocytochemistry; D007031:Hypothalamus / Q000032:analysis*; D007118:Immunoassay; D009074:Melanocyte-Stimulating Hormones / Q000032:analysis*; D009474:Neurons / Q000032:analysis*; D051381:Rats; D008083:beta-Lipotropin / Q000032:analysis*
D001679:Biogenic Amines; D004723:Endorphins; D000324:Adrenocorticotropic Hormone; D009074:Melanocyte-Stimulating Hormones; D008083:beta-Lipotropin; D004298:Dopamine
Analyse immunocytologique, dans l'hypothalamus du rat, des neurones producteurs de peptides de type endorphine. ACTH, MSH et beta-LPH. Etude comparative avec d'autres neurones peptidergiques et monoaminergiques.