title: [Changes in the morpho-functional properties of gastric parietal cells during activation of secretory activity].
abstract: Electron--microscope and biochemical studies in rats and dogs showed that secretory membranes of parietal cells were in dynamic equilibrium with plasmalemma in activated secretion. During secretion, a transposition of secretory membranes occurs: 53.2% of tubulovesicular membranes transform into membranes of intracellular canaliculi and apical surface. K+--ATPace and carbonic anhydrase activities increased (55.5% and 62.9%, resp.). The system of secretory membranes and enzyme systems of parietal cells seem to take part synchronously in the process of gastric acid secretion.
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D001639:Bicarbonates / Q000378:metabolism; D002256:Carbonic Anhydrases / Q000378:metabolism; D002462:Cell Membrane / Q000648:ultrastructure; D004435:Eating; D005753:Gastric Mucosa / Q000166:cytology* / Q000378:metabolism / Q000648:ultrastructure; D008274:Magnesium / Q000494:pharmacology; D008297:Male; D009940:Organoids / Q000648:ultrastructure; D010418:Pentagastrin / Q000494:pharmacology; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism
chemical_list: D001639:Bicarbonates; D000251:Adenosine Triphosphatases; D002256:Carbonic Anhydrases; D000254:Sodium-Potassium-Exchanging ATPase; D010418:Pentagastrin; D008274:Magnesium
vernacular_title: Izmenenie morfo-funktsional'nykh svoĭstv parietal'nykh kletok zheludka pri aktivatsii sekretornoĭ deiatel'nosti.