Fatal paralytic ileus complicating phenothiazine therapy.
The occurrence of fatal paralytic ileus with peritonitis in a patient receiving phenothiazines and an antiparkinsonian agent is described. Although sporadic reports of this complication have appeared, it has not been emphasized in the literature. Only by being alert to this problem can one hope to achieve earlier diagnosis and begin prompt and appropriate treatment.
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001590:Benztropine / Q000009:adverse effects / Q000627:therapeutic use; D002746:Chlorpromazine / Q000009:adverse effects / Q000627:therapeutic use; D003106:Colon / Q000473:pathology; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D007415:Intestinal Obstruction / Q000139:chemically induced*; D007418:Intestinal Pseudo-Obstruction / Q000139:chemically induced* / Q000401:mortality / Q000473:pathology; D010538:Peritonitis / Q000150:complications; D012559:Schizophrenia / Q000188:drug therapy; D014268:Trifluoperazine / Q000009:adverse effects / Q000627:therapeutic use
D014150:Antipsychotic Agents; D001590:Benztropine; D014268:Trifluoperazine; D002746:Chlorpromazine