title: [Biological characteristics of the plaque variants of the swine vesicular disease virus].
abstract: The Swine Vesicular Disease virus yields a heterogenic plaque population consisting of large round plaques of 8-10 mm, small uniform plaques with slightly indented contours, measuring 1-3 mm, and single plaques of transient form and size. The reisolates of the large (Lpf) plaques give a population that is similar to the initial virus, while the cloning of the small (Mpf) plaques leads to a homogenic population of such plaques. In vivo, the virus of the large plaques manifests enhanced virulence for swine. On the other hand, the selected small-plaque variant is apathogenic, which makes it possible to produce a live avirulent vaccine.
mesh_terms: D000818:Animals; D004770:Enterovirus / Q000235:genetics*; D004771:Enteroviruses, Porcine / Q000235:genetics*; D014644:Genetic Variation; D013552:Swine; D013555:Swine Vesicular Disease / Q000382:microbiology; D010948:Viral Plaque Assay; D014774:Virulence; D014776:Virus Cultivation
vernacular_title: Biologichna kharakteristika na plakovi varianti pri virusa na vezikuloznata bolest po svinete.