Nephroblastoma. Results and complications of treatment.
Treatment results in 31 patients with nephroblastoma are reported. Survival seemed superior in patients who received Actinomycin-D in addition to surgery and postoperative irradiation. Twelve long-term surviving children were evaluated for side-effects of the treatment. Although inhibition of growth and other abnormalities occurred in most survivors, little permanent disability and dysfunction appears to have resulted from the treatment.
D000273:Adipose Tissue / Q000528:radiation effects; D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003609:Dactinomycin / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy*; D007738:Kyphosis / Q000209:etiology; D008297:Male; D009392:Nephrectomy; D011379:Prognosis; D011878:Radiotherapy / Q000009:adverse effects; D012600:Scoliosis / Q000209:etiology; D009396:Wilms Tumor / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy*
D000970:Antineoplastic Agents; D003609:Dactinomycin