[Effect of small doses of diphtheria exotoxin on cell cultures].
High diphtheria exotoxin concentrations induced irreversible injuries to all the cultures under study (L, HeLa, spcv pzM). However, its final titres in the mentioned cells differed. HeLa and pzM cells, being highly sensitive, can be recommended for titration of dipheria exotoxin, instead of the expensive guinea pig tests. Low (subtoxic) doses produced cytoproliferative action and caused changes of the cell properties.
D000818:Animals; D002143:Callitrichinae; D004167:Diphtheria Toxin / Q000008:administration & dosage / Q000032:analysis / Q000633:toxicity*; D006367:HeLa Cells; D007668:Kidney / Q000196:embryology; D007739:L Cells; D008938:Mitosis; D013552:Swine; D014721:Vesicular stomatitis Indiana virus / Q000472:pathogenicity
D004167:Diphtheria Toxin
Deĭstvie malykh doz difteriinogo ékzotoksina na kul'tury kletok.