[Endobronchial Abrikosov's tumor. Two new cases associated to malignant tumors].
Endobronchial localizations of the granular cell tumours or Abrikossoff's tumour are very rare (6%) but their association with malignant tumours is exceptional and perhaps fortuitous. The clinical manifestations are generally the consequence of bronchial erosion and blocking. Bronchial endoscopy is the essential examination which allows the tumour to be seen and a biopsy to be made. Pathological examination confirms the diagnosis. The typicall cell of granular cell tumour is a large, polygonal one with finely granular eosinophilic cytoplasm and a small dark vesicular nucleus. Such cells are arranged in syncytial masses containing long, spindleshape cells with elongated nuclei. If the optical and elctron microscope description is well known, the histogenesis of the disease is still in dispute; the neurogenic origin seems to be the best one, but at present there is not enough evidence to make this assumption a certainty. Surgical exeresis is the only therapy to bring about a cure, but clinical supervision is necessary because of a possible relapse.
D000328:Adult; D001984:Bronchial Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009379:Neoplasms, Muscle Tissue / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography; D012878:Skin Neoplasms / Q000556:secondary; D014062:Tongue Neoplasms / Q000556:secondary
Tumeur d'Abrikossoff endobronchique. A propos de deux nouveaux cas associés à des tumeurs malignes.