title: [Antibody formation in type A viral hepatitis].
abstract: Immune response to hepatitis type A antigen (HAAg) was measured by the passive hemagglutination test (PHA) and by the immune adherence test (IAHA). Specific antibodies found by PHA are of the IgM class which indicates a recent exposure to hepatitis A virus. The antibodies found by IAHA reflect the level of postinfectious immune status. The antibody curve is highest in the age group of 30--49 years (95%). The above-mentioned serological tests were carried out with purified by gel filtration in Sepharose 6B Botevgrad faecal morphologically consisting of 27 nm particles with the buoyant density in CcCl of 1.40 g/ml. The same particles were aggregated with sera positive for antibody to hepatitis type A antigen in immune electron microscopy (IEM).
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral; D002031:Bulgaria; D002648:Child; D002675:Child, Preschool; D003168:Complement Fixation Tests; D004196:Disease Outbreaks; D006386:Hemagglutination Tests; D006506:Hepatitis A / Q000453:epidemiology / Q000276:immunology* / Q000635:transmission; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D007104:Immune Adherence Reaction; D008875:Middle Aged
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral
vernacular_title: Izuchenie antiteloobrazovaniia pri virusnom gepatite tipa A.