title: Effect of 5-phosphoribosyl-a-pyrophosphate on de novo pyrimidine biosynthesis in cultured Ehrlich ascites cells made permeable with dextran sulfate 500.
mesh_terms: D000227:Adenine Nucleotides / Q000494:pharmacology; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D002463:Cell Membrane Permeability; D002478:Cells, Cultured; D003911:Dextrans / Q000494:pharmacology*; D005947:Glucose / Q000494:pharmacology; D007700:Kinetics; D051379:Mice; D009962:Orotate Phosphoribosyltransferase / Q000378:metabolism; D010428:Pentosephosphates / Q000494:pharmacology*; D010754:Phosphoribosyl Pyrophosphate / Q000494:pharmacology*; D011743:Pyrimidines / Q000096:biosynthesis*; D012268:Ribose-Phosphate Pyrophosphokinase / Q000378:metabolism
chemical_list: D000227:Adenine Nucleotides; D003911:Dextrans; D010428:Pentosephosphates; D011743:Pyrimidines; D010754:Phosphoribosyl Pyrophosphate; D009962:Orotate Phosphoribosyltransferase; D012268:Ribose-Phosphate Pyrophosphokinase; D005947:Glucose