Renal transplantation in patients with bilateral Wilm's tumor.
Review of cases and of published reports of patients with bilateral Wilms' tumor revealed a significantly higher mortality rate in those who had received a renal transplant than in those who had not. The increased mortality is attributed to overwhelming sepsis resulting from chemotherapy, radiotherapy and immunosuppression. Growth of the tumor did not appear to be accelerated by immunosuppression and transplantation.
D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000401:mortality / Q000601:surgery* / Q000628:therapy; D016030:Kidney Transplantation; D011183:Postoperative Complications; D018805:Sepsis / Q000209:etiology; D014184:Transplantation, Homologous; D009396:Wilms Tumor / Q000401:mortality / Q000601:surgery* / Q000628:therapy