title: Recombination of carbon monoxide with hemoglobin after flash photolysis of the carboxyderivative in mixed solvents at subzero temperature.
abstract: The kinetics of recombination of carbon monoxide to hemoglobin produced by total flash photolysis of its carboxyderivative are studied at low temperatures (down to --55 degrees C) in mixed hydroalcoholic solvents. The rates are found to be different in two solvents used, namely ethylene glycol/buffer and methanol/buffer; for the former, the rates at subzero temperatures are simply explained by cooling and are consistent with the activation energy as measured in aqueous solution, while those in methanol/buffer show evidence of a specific solvent effect. Values are reported for the rate constants and activation energies in the two solvents.
mesh_terms: D002248:Carbon Monoxide / Q000097:blood*; D002263:Carboxyhemoglobin; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003080:Cold Temperature; D005026:Ethylene Glycols; D006454:Hemoglobins / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D000432:Methanol; D008722:Methods; D010782:Photolysis; D012997:Solvents; D013997:Time Factors; D014783:Viscosity
chemical_list: D005026:Ethylene Glycols; D006454:Hemoglobins; D012997:Solvents; D002248:Carbon Monoxide; D002263:Carboxyhemoglobin; D000432:Methanol