title: Stability-indicating assay for pivmecillinam hydrochloride and pivmecillinam hydrochloride capsules.
abstract: A high-pressure liquid chromatographic assay has been developed for pivmecillinam hydrochloride and pivmecillinam hydrochloride capsules. The method separates five reported degradation products and a number of esterified, related compounds. The accuracy of this method is comparable to the published ultraviolet assay and the relative standard deviation of a series of six replicate assays was better than +/- 0.7%.
mesh_terms: D000561:Amdinocillin Pivoxil / Q000032:analysis*; D002214:Capsules; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004355:Drug Stability; D010397:Penicillanic Acid / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D002214:Capsules; D000561:Amdinocillin Pivoxil; D010397:Penicillanic Acid