title: Rapid purification of lymphocytic choriomeningitis virus by density gradient centrifugation in colloidal silica.
abstract: Lymphocytic choriomeningitis virus was purified from cell culture fluid by density gradient centrifugation in colloidal silica. The specific infectivity increased 5000-fold and the recovery of infectivity was about 10%.
mesh_terms: D002460:Cell Line; D002499:Centrifugation, Density Gradient; D003102:Colloids; D008217:Lymphocytic choriomeningitis virus / Q000254:growth & development / Q000302:isolation & purification*; D008722:Methods; D012822:Silicon Dioxide
chemical_list: D003102:Colloids; D012822:Silicon Dioxide