[Neural regulation of coronary circulation].
In anesthetized dogs, with the aid of catheterization and perfusion of the coronary arteries roith heporinesed blood, catheterization of the heart cavities, and synchronous recording of the hemodynamics in unopened thorax, the mechanisms of neural regulation of the coronary circulation were analysed. Tonic effects of the nervous system on the coronary vessels are insignificant, coronary resistance being maintained by the high basal tonus. The cholinergic and adrenergic mechaniseins interact with the more powerful metabolic mechanisms. The concrete interrelationships between the cholinergic and the adrenergic mechanisms in the heart adrenergic responses as well as their probable physiological significance, are discussed.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001341:Autonomic Nervous System / Q000502:physiology*; D003326:Coronary Circulation; D003331:Coronary Vessels / Q000294:innervation*; D004285:Dogs; D004837:Epinephrine / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology; D010646:Phentolamine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D011942:Receptors, Adrenergic, alpha / Q000502:physiology; D011943:Receptors, Adrenergic, beta / Q000502:physiology; D011976:Receptors, Muscarinic / Q000502:physiology; D011978:Receptors, Nicotinic / Q000502:physiology; D014655:Vascular Resistance
D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D011976:Receptors, Muscarinic; D011978:Receptors, Nicotinic; D001285:Atropine; D011433:Propranolol; D009638:Norepinephrine; D004837:Epinephrine; D010646:Phentolamine
Nervnaia reguliatsiia koronargnogo krovoobrashcheniia.