Effects of isocaloric supplements of glucose or soyabean oil on lipids in tissues and plasma lipoproteins of starved and overfed chicks.
Chicks were overfed a basic diet supplemented isocalorically by soyabean oil or glucose 1, 2 and 10 days after 1 day of starvation. Carcass lipids resumed the prestarvation level 1 and 2 days after overfeeding with oil or glucose, respectively. After 10 days, an equal amount of lipid, mainly triglycerides, accumulated in the carcasses of both supplement groups. In the liver a transient accumulation of lipid was noticed in the oil-supplemented groups while a continuous increase was found in the glucose-supplemented ones. Hyperlipemia, due essentially to very low density lipoprotein (VLDL), was concomitant to liver lipid concentration. After 1 day, oil overfeeding raised plasma VLDL 6-fold, while the same level of VLDL was obtained within 2 days with glucose supplement. After 10 days, hyperlipemia was reduced in the oil-supplemented group, while it increased in the glucose-supplemented one. The fatty acid fluctuation caused by the treatments in liver lipids and plasma VLDL were grossly similar: the level of linoleic acid was reduced by glucose and increased by oil supplementation; the linoleic acid increase in VLDL preceeded that of liver lipids in the oil-supplemented groups. The results indicate a delayed transport of newly synthesized hepatic lipids in glucose-supplemented animals.
D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001835:Body Weight; D002645:Chickens; D002784:Cholesterol / Q000378:metabolism; D004041:Dietary Fats / Q000008:administration & dosage / Q000494:pharmacology*; D002149:Energy Intake; D004734:Energy Metabolism; D005227:Fatty Acids / Q000032:analysis; D005947:Glucose / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*; D050356:Lipid Metabolism; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood*; D008297:Male; D009821:Oils; D009929:Organ Size; D010743:Phospholipids / Q000378:metabolism; D013025:Glycine max; D013217:Starvation; D014280:Triglycerides / Q000378:metabolism
D004041:Dietary Fats; D005227:Fatty Acids; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D009821:Oils; D010743:Phospholipids; D014280:Triglycerides; D002784:Cholesterol; D005947:Glucose