title: X chromatin and aging.
abstract: X chromatin analysis of 30 aged and 30 control women failed to confirm X chromosome loss as responsible for the increase in incidence of hypodiploid cells observed with increasing age in women. No evidence was found to support a previously suggested relationship between X chromosome loss and the loss of mental function (senility) as measured by psychological tests.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D003704:Dementia / Q000235:genetics; D005260:Female; D006801:Humans; D007360:Intelligence; D012728:Sex Chromatin; D012730:Sex Chromosomes; D013223:Statistics as Topic