title: Ceramic hydroxylapatite as a plaque growth and drug screening substrate.
abstract: A new polycrystalline form of hydroxylapatite, CHA, has been shown to closely mimic dental enamel, in vitro, in regard to rate and degree of plaque formation and effectiveness of antiplaque drugs. The material has successfully been exploited as a standardized hydroxylapatite plaque growth substrate in conjuntion with a mass antidental plaque drug screening program.
mesh_terms: D001031:Apatites / Q000138:chemical synthesis; D002516:Ceramics; D003773:Dental Plaque / Q000188:drug therapy* / Q000382:microbiology; D004353:Drug Evaluation, Preclinical; D013295:Streptococcus mutans / Q000187:drug effects; D013499:Surface Properties; D014075:Tooth Discoloration / Q000139:chemically induced
chemical_list: D001031:Apatites