Effect of a carious dentin softener on the dentin and pulp.
The application of GK-101 to carious dentin softens the first or outer layer which contains denatured collagen. The second or inner layer of carious dentin, containing normal collagen fibers, is unaffected. The pulps of dog teeth were not affected by applying the solution to freshly prepared sound dentin.
D000818:Animals; D003731:Dental Caries / Q000473:pathology*; D003782:Dental Pulp / Q000187:drug effects*; D003804:Dentin / Q000187:drug effects* / Q000473:pathology; D004285:Dogs; D005998:Glycine / Q000031:analogs & derivatives* / Q000494:pharmacology; D006244:Hardness; D006801:Humans
D005998:Glycine