title: Antibody formation and cell-mediated immunity to dog pulp tissue altered by N2 paste via the root canal.
abstract: 1. N2 paste when incubated with dog pulp tissue renders it antigenically active. 2. Specific systemic circulating antibody to dog pulp tissue altered by N2 paste was obtained. 3. When dog pulp tissue was altered by N2 paste a specific lymphocyte stimulation resulted. 4. The root canal is an effective mode of immunization.
mesh_terms: D000818:Animals; D000906:Antibodies / Q000032:analysis; D000917:Antibody Formation; D000941:Antigens; D003782:Dental Pulp / Q000276:immunology*; D003786:Dental Pulp Cavity / Q000276:immunology; D004285:Dogs; D005557:Formaldehyde / Q000276:immunology*; D007111:Immunity, Cellular; D007114:Immunization; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D009336:Necrosis / Q000276:immunology; D012387:Root Canal Filling Materials / Q000276:immunology*
chemical_list: D000906:Antibodies; D000941:Antigens; D012387:Root Canal Filling Materials; D005557:Formaldehyde