High molecular fibrin derivatives in pre-eclamptic and eclamptic patients.
Soluble fibrin monomer complexes were assayed by agarose gel filtration and by ultracentrifugation. Increased values of SFMC were found in the normal third-trimester pregnancies. They were considerably higher in plasma of patients with pre-eclampsia. Concentrations were higher using ultracentrifugation as compared to gel chromatography. Using ultracentrifugation 4 components were identified, indicating that SFMC in this disease are not a homogeneous group.
D002847:Chromatography, Agarose; D004461:Eclampsia / Q000097:blood*; D004592:Electrophoresis, Starch Gel; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000097:blood*; D006801:Humans; D008970:Molecular Weight; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D014461:Ultracentrifugation
D005338:Fibrin Fibrinogen Degradation Products; C011468:fibrinmonomer