Serotonin and monoamine oxidase in mouse skin: effects of cigarette smoke exposure.
Mice were exposed to either air or cigarette smoke and the content and uptake of serotonin and activity of monoamine oxidase were determined. Serotonin concentration increased as a function of the frequency of exposure, while serotonin uptake by the skin was maximally increased after two 8 min. exposures. MAO activity for serotonin, but not for tyramine, was decreased by cigarette smoke exposure of more than 8 min.
D000818:Animals; D008297:Male; D051379:Mice; D008995:Monoamine Oxidase / Q000378:metabolism*; D010947:Plants, Toxic; D012701:Serotonin / Q000378:metabolism*; D012867:Skin / Q000201:enzymology / Q000378:metabolism*; D012907:Smoking; D014026:Nicotiana; D014439:Tyramine / Q000378:metabolism
D012701:Serotonin; D008995:Monoamine Oxidase; D014439:Tyramine