Leukaemic involvement of the pleura. A case report.
In chronic myelocytic leukaemia (CML), the pleura is a most uncommon site of extramedullary involvement. A 34-year-old man with CML presented with a massive pleural effusion. His peripheral blood contained few blast cells and the leucocyte alkaline phosphatase level was low. Cytological examination of the pleural fluid revealed cells with the morphological features of myeloblasts and monoblasts. The patient was treated with systemic chemotherapy, with no effect on the leukaemic pleural effusion.
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002908:Chronic Disease; D006801:Humans; D007951:Leukemia, Myeloid / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D008297:Male; D010996:Pleural Effusion / Q000166:cytology / Q000000981:diagnostic imaging / Q000209:etiology*; D011859:Radiography
D000970:Antineoplastic Agents