Chemical characterization of murine Ia alloantigens determined by the i-E/i-C subregions of the H-2 complex.
Alloantisera directed against the alloantigens determined by the I-E and I-C subregions of the murine major histocompatibility complex precipitate two components that have molecular weights of 35,000 and 29,000. These components, when analyzed by partial NH2-terminal sequencing, show no homology to two components of similar size determined by the I-A subregion. However, the large chain determined by the murine I-E and/or I-C subregion is homologous to the large chain of the human HLA-D region alloantigen, although the small chains isolated from these two species do not display any such homology.
D000595:Amino Acid Sequence; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D006183:H-2 Antigens; D051379:Mice / Q000276:immunology*; D008970:Molecular Weight; D013154:Spleen / Q000276:immunology
D006183:H-2 Antigens
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