title: [Urinary uropepsin activity in patients with encephalomalacia as an index of the activity of the hypothalamo- hypophyseal-adrenal axis].
abstract: The determinations were carried out in 25 patients with thrombotic encephalomalacia. The changes in 24-hour urine uropepsin activity were studied after administration of metopirone and dexamethasone. The uropepsin activity in a sample of 24-hour urine was determined by the method of West, Ellis and Scott. A statistically significant fall of uropepsin activity was observed in 24-hour urine after metopirone, with a rise in the activity of this enzyme after dexamethasone administration.
mesh_terms: D000368:Aged; D004678:Encephalomalacia / Q000503:physiopathology / Q000652:urine*; D010450:Endopeptidases / Q000652:urine*; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology*; D008875:Middle Aged; D010913:Pituitary-Adrenal System / Q000503:physiopathology*
chemical_list: D010450:Endopeptidases
vernacular_title: Aktywność uropepsyny w moczu chorych z rozmieknieniem mózgu jako wykładnik aktywności układu podwzgórze--przysadka--nadnercza.