title: Melatonin concentration in human blood and cerebrospinal fluid: relationship to stress.
abstract: In 35 daytime paired blood and cerebrospinal fluid (CSF) samples from 15 patients, melatonin levels in CSF were undetectable or detectable but not higher than blood levels. During pneumoencephalography in 6 patients, no significant elevation of blood melatonin levels was observed, whereas cortisol concentration increased.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008550:Melatonin / Q000097:blood / Q000134:cerebrospinal fluid*; D008875:Middle Aged; D011011:Pneumoencephalography; D013312:Stress, Physiological / Q000503:physiopathology*
chemical_list: D008550:Melatonin; D006854:Hydrocortisone