In vitro antiplaque effects of antiseptic phenols.
Several phenols known to be antiseptics were tested in vitro for their ability to adsorb to saliva-coated enamel and subsequently inhibit plaque formation. 3,5,4'-tribromosalicylanilide was found to be effective against growth and plaque formation of A viscosus, A naeslundii, S mutans and S sanguis. Dibromsalicil was effective against A viscosus. The other phenols (hexylresorcinol, thymol, phenylphenol and zinc phenolsulfonate) did not inhibit in vitro growth or plaque formation.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects; D001970:Bromobenzoates / Q000627:therapeutic use; D002417:Cattle; D003773:Dental Plaque / Q000382:microbiology / Q000517:prevention & control*; D006604:Hexylresorcinol / Q000627:therapeutic use; D010636:Phenols / Q000494:pharmacology / Q000627:therapeutic use*; D012458:Salicylanilides / Q000627:therapeutic use; D012459:Salicylates / Q000627:therapeutic use; D012995:Solubility; D013943:Thymol / Q000627:therapeutic use; D014867:Water; D015032:Zinc / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D001970:Bromobenzoates; D010636:Phenols; D012458:Salicylanilides; D012459:Salicylates; D014867:Water; D013943:Thymol; C013931:dibromsalicil; D015032:Zinc; D006604:Hexylresorcinol