title: Possible mechanisms for the genesis of common chromosome abnormalities, including isochromosomes and the philadelphia chromosome.
mesh_terms: D002503:Centromere; D002869:Chromosome Aberrations; D002900:Chromosomes, Human, 1-3; D002904:Chromosomes, Human, 21-22 and Y; D002906:Chromosomes, Human, 6-12 and X; D003434:Crossing Over, Genetic / Q000187:drug effects; D005260:Female; D006801:Humans; D007938:Leukemia / Q000235:genetics*; D007951:Leukemia, Myeloid / Q000235:genetics; D008297:Male; D008937:Mitomycins / Q000494:pharmacology; D009369:Neoplasms / Q000235:genetics*; D014178:Translocation, Genetic; D014314:Trisomy
chemical_list: D008937:Mitomycins