Prevalence of HBs-Ag in schistosomiasis. (A) general aspects.
Nine hundred and sixteen schistosomal patient together with 97 non-schistosomal controls were examined for the presence of HBs-Ag and anti-HBs in their sera by counter-immunoelectrophoresis (CIEP). The results are reported and statistically analysed. HBs-Ag, anti-HBs and the exposure rate were found significantly higher in schistosomal patients than in controls. The frequency of HBs-Ag was not significantly different in the active and inactive schistosomal groups, while the anti-HBs was significantly higher in the inactive group. S. mansoni-infected cases showed significantly higher frequency of HBs-Ag and anti-HBs than cases with S. haematobium. The prevalence of HBs-Ag was highest between 20-39 years of age in the schistosomal group, while the anti-HBs was maximum at the age of 30-39 years. There were no sex differences in the prevalence of HBs-Ag and anti-HBs in both schistosomal and control groups. However, a significantly higher frequency of anti-HBs was found between male patients and male controls. The same was true for females. Patients with history of parenteral anti-bilharzial treatment and blood transfusions were accompanied with significantly higher percentage of HBs-Ag and anti-HBs. The importance and significance of the results are discussed.
D000328:Adult; D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D001803:Blood Transfusion; D003378:Counterimmunoelectrophoresis; D004534:Egypt; D005260:Female; D006510:Hepatitis B Antibodies / Q000032:analysis*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D012548:Schistosoma haematobium / Q000302:isolation & purification; D012550:Schistosoma mansoni / Q000302:isolation & purification; D012552:Schistosomiasis / Q000188:drug therapy / Q000276:immunology*; D012556:Schistosomicides / Q000627:therapeutic use; D012737:Sex Factors
D000914:Antibodies, Viral; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D012556:Schistosomicides