The incorporation of 3H (G) L-leucine into single muscle fibers in Duchenne dystrophy and Charcot-Marie Tooth disease.
The results are reported of single muscle fiber uptake of tritiated leucine in muscle biopsy material from Duchenne dystrophy and Charcot-Marie Tooth disease. The uptake in the two conditions is compared and suggests that the previously reported increase in synthesis of cytoplasmic proteins in muscular dystrophy are probably related to regenerative efforts by the muscle fibers.
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002607:Charcot-Marie-Tooth Disease / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007930:Leucine / Q000378:metabolism*; D008875:Middle Aged; D009132:Muscles / Q000378:metabolism*; D009133:Muscular Atrophy / Q000378:metabolism*; D009136:Muscular Dystrophies / Q000378:metabolism*
D007930:Leucine