title: A case of Gilles de la Tourette's syndrome accompanied with alcoholism.
abstract: A case of Gilles de la Tourette's syndrome with alcoholism and migraine is described. Multiple motor tics and coprolalia were suppressed by the treatment with haloperidol. The concentration of HVA and 5-HIAA in the cerebrospinal fluid were measured and increment of HVA concentrations was outstanding while his symptoms were aggravated. This might be evidence for hyperactivity of dopaminergic neurons involved in manifest symptomatology of this syndrome.
mesh_terms: D000437:Alcoholism / Q000150:complications*; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D005879:Tourette Syndrome / Q000150:complications* / Q000188:drug therapy / Q000209:etiology
chemical_list: D006220:Haloperidol