title: The effects of root shape and biology on bone growth.
abstract: A statistical study was carried out on the influence of root surfaces on adjacent cellular activity. This activity is indeed affected by both the shape and the biology of those surfaces. Flat surfaces tend to inhibit, nicked surfaces tend to stimulate bone formation in a bone-growing environment. A biologic effect is exerted by the matrix of diseases roots. They contain an inhibitory principle which is not present in healthy roots. This factor is masked by the apatite structure and is destroyed by heat.
mesh_terms: D000818:Animals; D001695:Biology; D001846:Bone Development; D001853:Bone Marrow / Q000254:growth & development; D051381:Rats; D014092:Tooth Root / Q000033:anatomy & histology* / Q000502:physiology