title: Concealed accessory pathway and dual AV conduction: drug-dependent reentrant tachycardia.
abstract: Electrophysiological studies were performed in a patient with paroxysmal supraventricular tachycardia and a normal surface ECG at the time of the study. Premature atrial stimulation revealed dual AV conduction and an echo zone during AV conduction over the fast and the slow pathway. The prolongation of the AV conduction time by a calcium antagonist, Ro 11-1781, permitted the induction of tachycardias via both pathways. Premature ventricular stimulation yielded constant VA conduction times with activation of the low right atrium before the high right atrium before the left atrium. During the tachycardia, premature right ventricular beats conducted to the atrium at a time when the AV node and the His bundle would be refractory. The study suggests the simultaneous occurrence of an occult accessory bundle connecting the right ventricle to the right atrium and dual AV conduction.
mesh_terms: D000328:Adult; D002304:Cardiac Pacing, Artificial; D004562:Electrocardiography; D004594:Electrophysiology / Q000295:instrumentation / Q000379:methods; D006321:Heart / Q000187:drug effects; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008297:Male; D011437:Propylamines / Q000494:pharmacology; D013614:Tachycardia, Paroxysmal / Q000503:physiopathology*; D013976:Tiapamil Hydrochloride
chemical_list: D011437:Propylamines; D013976:Tiapamil Hydrochloride