title: Use of bupivacaine hydrochloride in oral surgery-a clinical study.
abstract: A study was developed in an attempt to investigate the possible usefulness of the local anesthetic agent, bupivacaine hydrochloride, for oral surgery. The results show that bupivacaine hydrochloride is an effective local anesthetic agent. It has a rapid onset time, a high frequency of surgical anesthesia, a long duration, and a low incidence of side effects. In comparison to lidocaine, bupivacaine has a greater potency, a lower toxicity at equipotent doses a longer duration, a possible pain-free period after return of normal sensation, and it does not require a vasoconstrictor for consistent profoundness.
mesh_terms: D000293:Adolescent; D000328:Adult; D000766:Anesthesia, Dental; D000772:Anesthesia, Local; D002045:Bupivacaine / Q000378:metabolism / Q000494:pharmacology; D005260:Female; D006801:Humans; D008012:Lidocaine; D008297:Male; D008340:Mandibular Nerve; D009407:Nerve Block; D013997:Time Factors; D014095:Tooth, Impacted / Q000601:surgery*
chemical_list: D008012:Lidocaine; D002045:Bupivacaine