title: The effects of fluoride on the percentage bacterial composition of dental plaque, on caries incidence, and on the in vitro growth of Streptococcus mutans, Actinomyces viscosus, and Actinobacillus sp.
abstract: Administration of 250 mug/ml NaF in drinking water to rats reduced both caries incidence (P less than 0.001) and the percentage of S mutans (0.01 greater than P greater than 0.001) although the percentage of Actinobacillus sp. was increased (P less than 0.001). An Actinobacillus sp. and S mutans FA1 both proliferated in NaF broth only if the NaF greater than 10 mug/ml, which was associated with the inhibition of acid production.
mesh_terms: D000188:Actinobacillus / Q000166:cytology / Q000187:drug effects*; D000190:Actinomyces / Q000166:cytology / Q000187:drug effects*; D000818:Animals; D001419:Bacteria / Q000187:drug effects*; D002452:Cell Count; D003731:Dental Caries / Q000209:etiology*; D003773:Dental Plaque / Q000382:microbiology*; D005459:Fluorides / Q000494:pharmacology*; D009055:Mouth / Q000382:microbiology; D051381:Rats; D012969:Sodium Fluoride / Q000494:pharmacology; D013295:Streptococcus mutans / Q000166:cytology / Q000187:drug effects*
chemical_list: D012969:Sodium Fluoride; D005459:Fluorides