Secretion of drugs by the parotid glands of rats and human beings.
The following drugs have been demonstrated to be secreted by the parotid glands of rats and human beings: amobarbital, chlorpromazine, codeine, glutethimide, meprobamate, pentobarbital, phenobarbital, and secobarbital. Methadone could not be detected in the parotid saliva of either rats or human beings, and morphine has been demonstrated only in parotid saliva of rats.
D000109:Acetylcholine / Q000494:pharmacology; D000328:Adult; D000654:Amobarbital / Q000378:metabolism; D000818:Animals; D001463:Barbiturates / Q000097:blood / Q000378:metabolism*; D002746:Chlorpromazine / Q000378:metabolism; D003061:Codeine / Q000378:metabolism; D005984:Glutethimide / Q000378:metabolism; D006801:Humans; D008297:Male; D008620:Meprobamate / Q000378:metabolism; D008691:Methadone / Q000378:metabolism; D009020:Morphine / Q000378:metabolism; D009294:Narcotics / Q000097:blood / Q000378:metabolism*; D010306:Parotid Gland / Q000187:drug effects / Q000378:metabolism*; D010424:Pentobarbital / Q000378:metabolism; D010634:Phenobarbital / Q000378:metabolism; D010862:Pilocarpine / Q000494:pharmacology; D051381:Rats; D012463:Saliva / Q000378:metabolism; D012631:Secobarbital / Q000378:metabolism; D014149:Tranquilizing Agents / Q000097:blood / Q000378:metabolism*
D001463:Barbiturates; D009294:Narcotics; D014149:Tranquilizing Agents; D010862:Pilocarpine; D012631:Secobarbital; D009020:Morphine; D008620:Meprobamate; D005984:Glutethimide; D000654:Amobarbital; D010424:Pentobarbital; D000109:Acetylcholine; D002746:Chlorpromazine; D008691:Methadone; D003061:Codeine; D010634:Phenobarbital