title: Enamel solubility reduction by acidulated phosphate-fluoride (APF) treatment.
abstract: The enamel solubility reducing (ESR) potential of acidulated phosphate-fluoride (APF) solutions containing varying amounts of F was studied. Commercial APF (1.23% F, pH 3.0) reduced solubility by about 80%. Fivefold dilutions of this APF were made with either phosphoric acid or water without significant effect on ESR potential. Further dilution to 0.12% F significantly decreased effectiveness. Commercially available APF products (1.23%) can be diluted several-fold with distilled water in the dental office without significant loss of ability to reduce the solubility of enamel.
mesh_terms: D000149:Acidulated Phosphate Fluoride / Q000494:pharmacology*; D003747:Dental Enamel Solubility / Q000187:drug effects*; D005459:Fluorides / Q000494:pharmacology*; D006801:Humans
chemical_list: D000149:Acidulated Phosphate Fluoride; D005459:Fluorides