Parasympathetic degeneration secretion of saliva in rats.
In rats under chloralose anaethesia saliva was found to flow from the submandibular and parotid glands previously subjected to (partial) postganglionic parasympathetic denervation. Secretion started in the submandibular glands 8.8-11.8 hours, and in the parotid glands 14.0-12.6 hours after the denervation and lasted about 7 hours in both glands. It was not abolished by sympatholytic drugs but by atropine. It is regarded as an example of the "degeneration activity" described in many organs and species and provides a method for prolonged stimulation of salivary glands in rats.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D003714:Denervation; D010275:Parasympathetic Nervous System / Q000502:physiology*; D010306:Parotid Gland / Q000294:innervation* / Q000378:metabolism; D051381:Rats; D012472:Salivation / Q000187:drug effects; D013363:Submandibular Gland / Q000294:innervation* / Q000378:metabolism
D001285:Atropine