Acute mesenteric ischaemia.
The experience of acute mesenteric ischaemia at St Vincent's Hospital, Melbourne, has been reviewed over 17 years. The mortality remains appallingly high. This applies particularly to those patients who had thrombosis of the superior mesenteric artery, amongst whom the mortality in this series was 97%. The mortality was slightly less in the group suffering from embolic occlusion of the superior mesenteric artery (66%), and in those suffering from thrombosis of the superior mesenteric vein (60%). A mortality of 66% was also found in patients suffering from non-occlusive gut ischaemia. Delay in diagnosis accounted for this high mortality. Early diagnosis is all-important, and this depends on the performance of mesenteric angiography in any patient suspected of having mesenteric ischaemia. Appropriate surgery may then be carried out in the occlusive group and supportive treatment, including intraarterial papaverine infusion, given to those with non-occlusive ischaemia. There is a pressing need for simple non-invasive tests to segregate those patients suffering from acute mesenteric ischaemia from those whose acute abdomen is due to some other cause.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D004617:Embolism / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D008297:Male; D008638:Mesenteric Arteries; D008641:Mesenteric Vascular Occlusion / Q000175:diagnosis / Q000601:surgery; D008642:Mesenteric Veins; D008875:Middle Aged; D013927:Thrombosis / Q000175:diagnosis / Q000601:surgery