title: Chronic myelogenous leukemia simulating chronic granulomatous disease.
abstract: A 5-year illness of a child, characterized by recurrent bacterial infections and abnormal results of nitroblue tetrazolium dye reduction tests, was suggestive of chronic granulomatous disease but the illness terminated in overt myeloid leukemia. During this progression studies of leukocyte structure and metabolic activity revealed abnormalities that suggested the existence of a "preleukemic" state.
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006105:Granulomatous Disease, Chronic / Q000175:diagnosis*; D006801:Humans; D007951:Leukemia, Myeloid / Q000175:diagnosis* / Q000378:metabolism; D007958:Leukocyte Count; D007962:Leukocytes / Q000378:metabolism; D009580:Nitroblue Tetrazolium; D010585:Phagocyte Bactericidal Dysfunction / Q000175:diagnosis*
chemical_list: D009580:Nitroblue Tetrazolium
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