Giant platelets and thrombocytopenia: a bleeding disorder in siblings. Clinical laboratory and electron microscopic aspects.
This report presents the findings of an inherited platelet abnormality in two members of the same family. The authors tested hemostasis of six normal and two abnormal members, studied the platelets using optical and electron microscopy, and genetic transmission in the family. The literature is also reviewed.
D000328:Adult; D001792:Blood Platelets / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008297:Male; D010375:Pedigree; D013921:Thrombocytopenia / Q000235:genetics* / Q000473:pathology