title: Fortnightly fluoride rinsing combined with topical painting of fluoride solutions containing Al-, Fe-, and Mn-ions.
abstract: The possibility of achieving a caries-reducing effect by a combination of fortnightly mouthrinsings with 0.2% NaF-solutions and topical painting with solutions containing Al-, Fe-, and Mn-ions was examined in a 4-year clinical study. In addition to the fluoride rinses one of two randomized groups was given three paintings per year with a 0.2% NaF-solution. The other group was painted three times per year with a potassium fluoride solution containing Al-, Fe-, and Mn-ions. This group developed significantly less caries during the study than the NaF-group. The results indicate that certain metal ions can enhance the caries-prophylactic action of the fluoride ions.
mesh_terms: D002648:Child; D004245:DMF Index; D004338:Drug Combinations; D004341:Drug Evaluation; D005459:Fluorides / Q000008:administration & dosage*; D005460:Fluorides, Topical / Q000008:administration & dosage*; D006801:Humans; D008670:Metals / Q000008:administration & dosage*; D009067:Mouthwashes; D009994:Osmolar Concentration; D012969:Sodium Fluoride / Q000008:administration & dosage*; D013997:Time Factors
chemical_list: D004338:Drug Combinations; D005460:Fluorides, Topical; D008670:Metals; D009067:Mouthwashes; D012969:Sodium Fluoride; D005459:Fluorides