The effect of topical application with an organic and inorganic fluoride compound on the inhibition of dental plaque in humans.
Accumulation of dental plaque for 3 and 7 days respectively was determined by calculating the difference between the postcollection and precollection weights of enamel slabs attached to orthodontic bands cemented to the upper first molars of 3 subjects. Pretreatment of the enamel slabs with amine-fluoride or -chloride respectively-at an equivalent amine concentration-prevented plaque deposition on the slabs, whereas pretreatment with sodium monofluorophosphate was less effective. The fluoride concentrations of all fluoride-pretreated enamel slabs were similar. No convincing demonstration of significant differences between the treatments could be predicted in view of the discrepancy in results at the 3- and 7-day test periods.
D000328:Adult; D000588:Amines / Q000494:pharmacology*; D002712:Chlorides / Q000494:pharmacology; D003743:Dental Enamel / Q000378:metabolism; D003773:Dental Plaque / Q000517:prevention & control*; D005459:Fluorides / Q000494:pharmacology*; D005460:Fluorides, Topical / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D008297:Male; D010710:Phosphates / Q000494:pharmacology*; D012969:Sodium Fluoride / Q000494:pharmacology*
D000588:Amines; D002712:Chlorides; D005460:Fluorides, Topical; D010710:Phosphates; D012969:Sodium Fluoride; D005459:Fluorides