Cell aggregates in malignant mesothelioma.
The finding in cell block sections of a central core of collagen within tumour aggregates in 4 out of 12 cases of effusions due to malignant mesothelioma is statistically significant (P greater than .01) when compared with its incidence in 2 of 80 cases of effusion due to metastatic carcinoma. It is suggested that this observation may be of diagnostic value in the cytologic evaluation of effusions when malignant mesothelioma is suspected.
D001202:Ascitic Fluid / Q000166:cytology*; D003094:Collagen; D003581:Cytodiagnosis; D003937:Diagnosis, Differential; D006801:Humans; D008654:Mesothelioma / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D009362:Neoplasm Metastasis; D010996:Pleural Effusion / Q000166:cytology*
D003094:Collagen