The aid of electron microscopy in the diagnosis of osteosarcoma of the bone (case report).
Osteogenic sarcoma with marked cellular anaplasia and little or no osteoid formation may present major problems in histologic identification. The application of electron microscopy is demonstrated in a case of a poorly differentiated osteosarcoma of the tibia. Unequivocal electron microscopic diagnostic findings are described in relation to light microscopic data.
D000293:Adolescent; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D012516:Osteosarcoma / Q000175:diagnosis* / Q000648:ultrastructure; D013977:Tibia