title: [Regulation of the breadth of the field of self recognition].
abstract: On the basis of certain cybernetic considerations, the need is demonstrated of several plasmatic circuits controlling the amplitude of the self recognition field. Regulating every individual circuit in a defense-enhancing direction is demonstrated to trigger a self-destroying, increasing-positive-retroaction mechanism, which is in turn controlled by an increasing-negative-retroactive defense-inhibiting mechanism. The existence is also demonstrated of a correlation between these retroaction processes. When certain stimulation levels are exceeded, such a correlation results in the growth of the negative process being sped up. The possibilities are discussed of stimulating the regulation of the circuit that governs the tumoral defense, keeping the negative retroaction below the limits at which it starts developing exponentially, thereby enhancing anticancer defenses.
mesh_terms: D003491:Cybernetics; D003674:Defense Mechanisms; D004198:Disease Susceptibility; D006801:Humans; D007113:Immunity, Innate; D012649:Self Concept
vernacular_title: Sulla regolazione dell'ampiezza del campo di reconoscimento del self.