title: Prevention of xerostomia-related dental caries in irradiated cancer patients.
abstract: Three caries preventative regimens: oral hygiene; oral hygiene and topical fluoride; and oral hygiene, typical fluoride, and sucrose restriction were evaluated in patients with cancer given xerostomia-producing radiotherapy. The oral hygiene-fluoride gel combination was remarkably effective in protecting these high risk patients from caries, regardless of the cariogenicity of the diet.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003731:Dental Caries / Q000209:etiology / Q000517:prevention & control*; D004032:Diet; D005260:Female; D005460:Fluorides, Topical / Q000627:therapeutic use; D005782:Gels; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009910:Oral Hygiene; D012472:Salivation / Q000528:radiation effects; D014987:Xerostomia / Q000209:etiology*
chemical_list: D005460:Fluorides, Topical; D005782:Gels