[Free amino acids in leukemic leukocytes].
Using the method of ion-exchange chromatography in automatic analyser the level of free amino acids was determined in peripheral blood leucocytes of 14 healthy blood donors and 36 patients with various types of leukaemia. In comparison with granulocytes the concentration of free amino acids in lymphocytes was reduced. The concentration of free amino acids in lymphocytes of chronic lymphatic leukemia was not essentially changed. The leucocytes in chronic myeloid leukemia showed a rise in the concentration of most free amino acids. In the blast cells of patients with acute myeloid the concentration of free amino acids was reduced in relation to DNA contents while in relation to proteins this concentration was raised.
D000328:Adult; D000596:Amino Acids / Q000097:blood*; D004273:DNA, Neoplasm / Q000097:blood; D005260:Female; D006801:Humans; D007938:Leukemia / Q000097:blood*; D007945:Leukemia, Lymphoid / Q000097:blood; D007951:Leukemia, Myeloid / Q000097:blood; D015470:Leukemia, Myeloid, Acute / Q000097:blood; D008297:Male
D000596:Amino Acids; D004273:DNA, Neoplasm
Wolne aminokwasy leukocytów białaczkowych