title: Laboratory studies in the management of soft contact lens use.
abstract: Laboratory procedures may be of great value in dealing with lens spoilation and in monitoring the state of the cornea during lens wear. Deposition of calcium-rich material remains the only defined non-mechanical process involved in spoilation although other forms of deposit and discolouration occur. Excess calcium levels in tear fluid are not a feature of contact lens wear, but changes in the sodium-potassium concentration ratio of tears are found. The basis for this effect is obscure but ratio changes may be useful empirical indices of corneal function.
mesh_terms: D000293:Adolescent; D002118:Calcium; D003263:Contact Lenses, Hydrophilic; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008297:Male; D011188:Potassium / Q000032:analysis; D012964:Sodium / Q000032:analysis; D013666:Tears / Q000032:analysis / Q000201:enzymology
chemical_list: D007527:Isoenzymes; D012964:Sodium; D007770:L-Lactate Dehydrogenase; D011188:Potassium; D002118:Calcium