[Concepts in therapy of the first relapse in acute lymphoblastic leukaemia: experience with 28 children (author's transl)].
In 10 out of 15 children with first relapse of ALL complete remission could be achieved by a combination of Adriamycin + Methylprednisolon followed by Asparaginase + Methylprednisolon. Median remission duration was 24 weeks. The results of this regimen proved superior to other regimens tested.
D000293:Adolescent; D001215:Asparaginase / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004317:Doxorubicin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D007223:Infant; D007945:Leukemia, Lymphoid / Q000188:drug therapy*; D008775:Methylprednisolone / Q000627:therapeutic use; D012008:Recurrence; D012075:Remission, Spontaneous; D013997:Time Factors
D004317:Doxorubicin; D001215:Asparaginase; D008775:Methylprednisolone
Behandlungswege für das 1. Rezidiv der akuten lymphoblastischen Leukämie (ALL): Erfahrungen an 28 Kindern