title: Increased appetite (bulimia) in Parkinson's disease.
abstract: Five patients with Parkinson's disease, when first seen, manifested an abnormal increase in appetite. This bulimia decreased concomitantly with clinical improvement in the parkinsonism during treatment with L-dopa plus a decarboxylase inhibitor. A possible role of dopamine in the central control of appetite is discussed. Abnormally increased appetite (bulimia) is proposed as a new autonomic sign in Parkinson's disease.
mesh_terms: D000368:Aged; D000547:Amantadine / Q000627:therapeutic use; D001068:Feeding and Eating Disorders / Q000209:etiology*; D005260:Female; D006801:Humans; D006815:Hunger; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000188:drug therapy
chemical_list: D007980:Levodopa; D000547:Amantadine