title: Ricin and modeccin do not inhibit the elongation factor 1-dependent binding of aminoacyl-tRNA to ribosomes.
abstract: Ricin and modeccin do not affect the total number of ribosomes to which phenylalanyl-tRNA becomes bound in the EF 1-dependent reaction. Previous inconsistencies resulted from the use of the nitrocellulose-filter technique, which overestimates the number of control ribosomes engaged in the binding reaction if trace amounts of EF 2 contaminate the ribosomal preparations.
mesh_terms: D037102:Lectins / Q000494:pharmacology*; D010445:Peptide Elongation Factors / Q000378:metabolism*; D010649:Phenylalanine; D012346:RNA, Transfer, Amino Acyl / Q000378:metabolism*; D054790:Ribosome Inactivating Proteins, Type 2; D012270:Ribosomes / Q000187:drug effects / Q000378:metabolism*; D012276:Ricin / Q000494:pharmacology*
chemical_list: D037102:Lectins; D010445:Peptide Elongation Factors; D012346:RNA, Transfer, Amino Acyl; D054790:Ribosome Inactivating Proteins, Type 2; D010649:Phenylalanine; C016004:modeccin; D012276:Ricin
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