title: Influence of different endodontic methods of treatment upon the process of apical closure of immature pulpless human teeth and the structure of the newly formed calcified tissue in apical opening.
abstract: A description is given of the pathohistological structure of the calcified tissue in the apical opening of four extracted immature pulpless human teeth treated by various endodontic methods. It is concluded that in the tooth treated by mortal extirpation there was neither histological healing nor any tendency for further apex formation. In both the tooth where vital extirpation was performed and in one of the teeth treated as apical periodontitis, the apices were formed from conglomerates of different calcified tissues, identical to the tissue which was formed under comparable conditions in experimental dogs. In the fourth human tooth also treated as apical periodontitis after treatment the apical opening closed with irregular dentine tissue. In this study consideration was given to the problem of the origin of the odontoblasts which co-exist with the hard destructive process present in some pulpless teeth. It is concluded that in the case presented in this study the irregular dentine was formed by the same odontoblasts which took part in the process of normal odontogenesis. This fact, should be respected in the course of endodontic treatment of immature pulpless teeth.
mesh_terms: D000818:Animals; D002126:Calcium Hydroxide / Q000494:pharmacology; D002164:Camphor / Q000494:pharmacology; D002725:Chloroform / Q000031:analogs & derivatives; D003782:Dental Pulp / Q000503:physiopathology; D003809:Dentin, Secondary / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D004285:Dogs; D006801:Humans; D007455:Iodine; D009804:Odontoblasts / Q000502:physiology; D010636:Phenols / Q000494:pharmacology; D011670:Pulpectomy; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D014074:Tooth Calcification; D014092:Tooth Root / Q000503:physiopathology*; D014945:Wound Healing
chemical_list: D010636:Phenols; D012387:Root Canal Filling Materials; D002164:Camphor; D002725:Chloroform; D007455:Iodine; D002126:Calcium Hydroxide