title: Inhaled nitrous oxide and cathepsin D activity in the lung.
abstract: Acute exposures of lungs to nitrous oxide in anesthetic concentration results in an initial lowered free activity of cathepsin D. Chronic exposures with either continuous or interrupted anesthetic exposure increases the free activity of this enzyme.
mesh_terms: D000769:Anesthesia, Inhalation; D000818:Animals; D002403:Cathepsins / Q000037:antagonists & inhibitors / Q000378:metabolism*; D005260:Female; D008168:Lung / Q000187:drug effects* / Q000201:enzymology; D008247:Lysosomes / Q000187:drug effects / Q000201:enzymology; D008297:Male; D009609:Nitrous Oxide / Q000494:pharmacology*; D051381:Rats
chemical_list: D002403:Cathepsins; D009609:Nitrous Oxide