Study of platelet aggregation in vivo: II. Effect of bencyclan on circulating metastatic tumor cells.
Circulation time of isotope labeled ascites tumor cells was measured after intravenous injection into mice. Circulation time was approximately doubled by pretreatment with the platelet aggregation inhibitor compound bencyclan.
D000818:Animals; D001537:Bencyclane / Q000494:pharmacology*; D002286:Carcinoma, Ehrlich Tumor / Q000473:pathology; D003508:Cycloheptanes / Q000494:pharmacology*; D008297:Male; D051379:Mice; D009362:Neoplasm Metastasis; D009374:Neoplasms, Experimental / Q000473:pathology; D009360:Neoplastic Cells, Circulating; D010974:Platelet Aggregation / Q000187:drug effects*; D013997:Time Factors
D003508:Cycloheptanes; D001537:Bencyclane