title: [Sacrococcygeal teratomas in children treated at the Oncological Clinic of the Mother and Child Institute in Warsaw].
abstract: During the years, 1962 through 1975, 27 children with sacrococcygeal teratomas were seen at the Oncological Department of the National Research Institute for Mother and Child in Warsaw. 13 teratomas were benign and 14 were malignant. Surgical removal through a sacral approach was the basis of the treatment. In the presacral tumors with great diameter two-phase method was performed (the first phase--trans-abdominal excision of the tumor and the second phase--excision of remnant tumor's pedicle with coccygeal bone resection). Monodrug chemotherapy (Cyclophosphamide, Actinomycin D) in malignant tumors was without effect. In the group of benign teratomas are alive 11 children, in the group of malignant teratomas only one child survived. Some profits are expected from the multidrug chemotherapy ( Methotrexate , Cyclophosphamide, Actinomycin D) associated with radiotherapy, this can make operable primarily inoperable tumors.
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000601:surgery / Q000628:therapy*; D002675:Child, Preschool; D003050:Coccyx; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011044:Poland; D011300:Preoperative Care; D011879:Radiotherapy Dosage; D012447:Sacrum; D013724:Teratoma / Q000601:surgery / Q000628:therapy*
vernacular_title: Potworniaki okolicy krzyzowo-guzicznej u dzieci w materiale Kliniki Onkologii Dzieci i Młodziezy Instytutu Matki i Dziecka w Warszawie.