Fetal blood sampling by fetoscopy in pregnant ewes.
Successful fetal blood sampling by fetoscopy is reported in 4 out of 6 pregnant ewes. No deleterious effect of the procedure on the course of pregnancy and fetal outcome could be demonstrated. There were two main problems: floating membranes and mobile fetal cotyledon vessels. Although the first problem could in part be overcome by infusion of saline, fetal blood sampling in the pregnant ewe is a rather difficult and time-consuming procedure.
D000818:Animals; D001800:Blood Specimen Collection / Q000379:methods*; D005260:Female; D005312:Fetal Blood; D005332:Fetoscopy; D008954:Models, Biological; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood*; D011296:Prenatal Diagnosis; D012756:Sheep