Failure of mice infected with Rauscher leukemia virus (RLV-A) to develop splenic colonies.
A progressive increase occurs in the CFU-S/10(6) spleen cells with the development of RLV-A-induced erythroleukemia. In addition, alteration of the spleen by the RLV-A appears to prevent the seeding and development of spleen colonies in infected mice.
D000818:Animals; D006412:Hematopoietic Stem Cells; D004915:Leukemia, Erythroblastic, Acute / Q000473:pathology*; D007942:Leukemia, Experimental / Q000473:pathology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D011925:Rauscher Virus; D013154:Spleen / Q000473:pathology*; D014412:Tumor Virus Infections / Q000473:pathology*