The Nail Patella syndrome--a report of a family.
This report describes two cases of the Nail Patella Syndrome with renal involvement. Pathological studies include immunochemistry, light microscopy, immunofluorescence and electron microscopy. The possibility of secondary immune damage to altered glomerular basement membrane is suggested as a cause of the progressive renal disease which occurs in some of these cases.
D000293:Adolescent; D000328:Adult; D001485:Basement Membrane / Q000473:pathology; D005260:Female; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D009261:Nail-Patella Syndrome / Q000235:genetics* / Q000473:pathology