Cardiac arrest due to hyperkalemia following therapy for acute lymphoblastic leukemia.
A patient with acute lymphoblastic leukemia with a large tumor burden is presented. Following successful chemotherapy, the patient experienced a cardiac arrest presumably due to hyperkalemia in association with hyperuricemia. The implication of these findings for patients with responsive hematological malignancies is discussed.
D000293:Adolescent; D000493:Allopurinol / Q000627:therapeutic use; D003630:Daunorubicin / Q000009:adverse effects / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006323:Heart Arrest / Q000097:blood / Q000209:etiology*; D006801:Humans; D006947:Hyperkalemia / Q000097:blood / Q000150:complications* / Q000209:etiology; D007945:Leukemia, Lymphoid / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D008297:Male; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use; D014527:Uric Acid / Q000097:blood; D014747:Vinblastine / Q000627:therapeutic use; D014750:Vincristine / Q000009:adverse effects
D014527:Uric Acid; D014750:Vincristine; D014747:Vinblastine; D000493:Allopurinol; D011241:Prednisone; D003630:Daunorubicin