Inhibition of lactation and ovarian function: a possible animal experimental model for humans.
Lactating Texel ewes are hyperprolactinemic. Hyperprolactinemia persists for at least the first 50 h after weaning, when the udder is swollen and tender. Oral administration of bromocriptine lowers hyperprolactinemia dramatically within 4 h, correlated with 'shrinking' of the udder. During lowering of hyperprolactinemia there is no immediate increase in LH.
D000818:Animals; D001971:Bromocriptine / Q000494:pharmacology; D005260:Female; D006801:Humans; D007774:Lactation / Q000502:physiology*; D008954:Models, Biological; D010060:Ovulation; D011247:Pregnancy; D011388:Prolactin / Q000378:metabolism*; D012756:Sheep
D001971:Bromocriptine; D011388:Prolactin