Relation between curability and tumor volume in a murine carcinoma and sarcoma.
Tumor control doses (TCD50) using single 60CO doses were determined on C3HBA adenocarcinoma and Dunn osteosaroma ranging in size from microscopic pulmonary colonies (3 X 13(-5) mm3) to palpable subcutaneous tumors (300 mm3) in the hind limb. The power function TCD50 =23.57 TV0.15, with TCD50 in GY and TV (tumor volume) in mm3, fits the data for both tumors over the entire range of tumor volumes used.
D000230:Adenocarcinoma / Q000532:radiotherapy*; D000818:Animals; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D008325:Mammary Neoplasms, Experimental / Q000532:radiotherapy*; D051379:Mice; D009367:Neoplasm Staging; D012516:Osteosarcoma / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D012513:Sarcoma, Experimental / Q000532:radiotherapy
D003037:Cobalt Radioisotopes