A case of acute myeloblastic leukemia with Ph1 chromosome showing translocation 9q+;22q-.
Cytogenetic studies of the bone marrow and peripheral blood with the quinacrine fluorescence banding technique in a patient with the clinical diagnosis of acute myeloblastic leukemia revealed the Philadelphia chromosome due to a translocation between chromosomes 22 and 9. He had been exposed to the atomic bomb in Hiroshima, and some hours after the exposure he wandered into the hypocenter.
D002869:Chromosome Aberrations; D002904:Chromosomes, Human, 21-22 and Y; D002906:Chromosomes, Human, 6-12 and X; D003561:Cytarabine / Q000627:therapeutic use; D006801:Humans; D007564:Japan; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000235:genetics*; D008297:Male; D015122:Mercaptopurine / Q000627:therapeutic use; D008875:Middle Aged; D009689:Nuclear Warfare; D011239:Prednisolone / Q000627:therapeutic use; D014178:Translocation, Genetic
D003561:Cytarabine; D011239:Prednisolone; D015122:Mercaptopurine