Inheritance patterns in recurrent aphthous ulcers: twin and pedigree data.
Nineteen sets of twins and 318 individuals from six families were examined and interviewed in order to ascertain whether a genetic component could be established for recurrent aphthous ulcers (RAU). While no specific mode of inheritance could be established, the data strongly support the hypothesis of a genetic factor involved in susceptibility to the disease.
D004200:Diseases in Twins; D005260:Female; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D010375:Pedigree; D011247:Pregnancy; D012008:Recurrence; D013281:Stomatitis, Aphthous / Q000235:genetics*; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic