title: Preserved scleral allografts in periodontal defects in man. II. Histological evaluation.
abstract: 1. The scleral grafts appeared to be well accepted as there were no signs of antigenicity or untoward reactions. 2. The gingival connective tissue, periodontal ligament and the periosteum were observed intertwined with sclera at the interface. 3. Sclera was invaded by host fibroblasts, capillaries, and appeared in some areas to be raplaced by a dense connective tissue. 4. Areas of cementogenesis could be observed in all specimens. 5. There were no signs of osteogenesis within the scleral grafts. 6. The alveolar crest appeared relatively nonreactive to sclera. 7. There were no signs of external root resorption or ankylosis. 8. Sclera may be able to be used to fill in osseous craters, other periodontal defects and as a scaffolding in conjunction with osseous grafts. This requires further investigation. 9. Sclera may possibly be used in areas where there was loss of gingival contour or need for ridge augmentation.
mesh_terms: D000539:Alveolar Process / Q000033:anatomy & histology; D003094:Collagen; D003238:Connective Tissue / Q000033:anatomy & histology; D005881:Gingiva / Q000033:anatomy & histology; D006801:Humans; D010510:Periodontal Diseases / Q000601:surgery*; D010513:Periodontal Ligament / Q000033:anatomy & histology; D010519:Periodontium / Q000502:physiology; D010521:Periosteum / Q000033:anatomy & histology; D012590:Sclera / Q000033:anatomy & histology / Q000502:physiology / Q000637:transplantation*; D014021:Tissue Preservation; D014184:Transplantation, Homologous; D014945:Wound Healing
chemical_list: D003094:Collagen