[Effect of mescaline on cerebral cholinesterases and on exploratory behavior in rats].
In this study the Authors had the purpose to evaluate the action of a psychotomimetic substance (mescaline) on behavior (exploring behaviour and spontaneous motility) and on cerebral biochemistry (cholinesterase activity) of rat. The mescaline has shown to be active both on behaviour (increasing the spontaneous motility) and on biochemistry (decreasing the total cholinesterase activity). From the examination of the results of this work it could be cautiously assumed the hypothesis that the behavioural effects of mescaline are related (at least partially) to modifications of the cholinergic system at the cerebral level.
D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000201:enzymology; D002091:Butyrylcholinesterase / Q000378:metabolism; D002802:Cholinesterases / Q000378:metabolism*; D005106:Exploratory Behavior / Q000187:drug effects*; D008297:Male; D008635:Mescaline / Q000494:pharmacology*; D009043:Motor Activity / Q000187:drug effects; D051381:Rats
D000110:Acetylcholinesterase; D002091:Butyrylcholinesterase; D002802:Cholinesterases; D008635:Mescaline
Azione della mescalina sulle colinesterasi cerebrali e sul comportamento esplorativo del ratto.