14C vitamin A in developing rat teeth and bone. A whole body-autoradiographic study.
The distribution of vitamin A in developing young rats has been studied. Low doses of 14C-retinol were administered intraperiotoneally and the uptake analyzed autoradiographically. The vitamin was found to accumulate mainly in the intestines, liver, kidney, adrenal and brown fat. No uptake could be detected in hard tissue forming cells nor in any hard tissue, except in the secretory ameloblasts of the incisors.
D002001:Adipose Tissue, Brown / Q000378:metabolism; D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D001345:Autoradiography; D001846:Bone Development; D001842:Bone and Bones / Q000378:metabolism*; D002250:Carbon Radioisotopes; D007274:Injections, Intraperitoneal; D007413:Intestinal Mucosa / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D051381:Rats; D014070:Tooth / Q000254:growth & development / Q000378:metabolism*; D014801:Vitamin A / Q000008:administration & dosage / Q000378:metabolism*
D002250:Carbon Radioisotopes; D014801:Vitamin A