Changes in thick filament length in Limulus striated muscle.
Here we describe the change in thick filament length in striated muscle of Limulus, the horseshoe crab. Long thick filaments (4.0 microns) are isolated from living, unstimulated Limulus striated muscle while those isolated from either electrically or K+-stimulated fibers are significantly shorter (3.1 microns) (P less than 0.001). Filaments isolated from muscle glycerinated at long sarcomere lengths are long (4.4 microns) while those isolated from muscle glycerinated at short sarcomere lengths are short (2.9 microns) and the difference is significant (P less than 0.001). Thin filaments are 2.4 microns in length. The shortening of thick filaments is related to the wide range of sarcomere lengths exhibited by Limulus telson striated muscle.
D008841:Actin Cytoskeleton / Q000648:ultrastructure*; D000818:Animals; D003599:Cytoskeleton / Q000648:ultrastructure*; D005990:Glycerol / Q000494:pharmacology; D006737:Horseshoe Crabs; D009132:Muscles / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure*; D012518:Sarcomeres / Q000648:ultrastructure
D005990:Glycerol
Biochim Biophys Acta. 1959 Jul;34:147-57
13815112
J Ultrastruct Res. 1963 Aug;49:156-65
14058440
J Ultrastruct Res. 1961 Apr;5:109-15
13720918
Nature. 1954 May 22;173(4412):973-6
13165698
Nature. 1954 May 22;173(4412):971-3
13165697
Science. 1976 Oct 29;194(4264):521-3
1085986
J Cell Biol. 1972 Oct;55(1):221-35
4120073
J Mol Biol. 1974 Sep 15;88(2):343-8
4452999
J Ultrastruct Res. 1973 May;43(3):313-43
4575715
J Mol Biol. 1974 Sep 25;88(3):693-709
4449125
Comp Biochem Physiol B. 1974 Jan 15;47(1):9-26
4810372