Glucocorticoids and carbohydrate metabolism in hypothermic and hibernating hamsters.
In hibernating hamsters carbohydrate reserves are regulated and are in dynamic equilibrium. During "deep" hypothermia (Tb 7-8 degrees C) hamsters undergo a progressive hypoglycemia, depletion of liver glycogen, and death within 24 hours. Glucocorticoid treatment results in enhanced blood and liver carbohydrates, prolonged survival at Tb 7-8 degrees C, and enhanced thermogenic capacity leading to arousal.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D050260:Carbohydrate Metabolism; D003348:Cortisone / Q000494:pharmacology; D006224:Cricetinae; D005938:Glucocorticoids / Q000494:pharmacology*; D006605:Hibernation / Q000187:drug effects; D007035:Hypothermia / Q000378:metabolism*; D008112:Liver Glycogen / Q000378:metabolism
D001786:Blood Glucose; D005938:Glucocorticoids; D008112:Liver Glycogen; D003348:Cortisone