Increased appetite (bulimia) in Parkinson's disease.
Five patients with Parkinson's disease, when first seen, manifested an abnormal increase in appetite. This bulimia decreased concomitantly with clinical improvement in the parkinsonism during treatment with L-dopa plus a decarboxylase inhibitor. A possible role of dopamine in the central control of appetite is discussed. Abnormally increased appetite (bulimia) is proposed as a new autonomic sign in Parkinson's disease.
D000368:Aged; D000547:Amantadine / Q000627:therapeutic use; D001068:Feeding and Eating Disorders / Q000209:etiology*; D005260:Female; D006801:Humans; D006815:Hunger; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000188:drug therapy
D007980:Levodopa; D000547:Amantadine