Noncoincidence of histone and DNA synthesis in cleavage cycles of early development.
The times of histone and DNA synthesis do not coincide in early cleavage of the sea urchin embryo. In fact, the production of histones increases during the interval after DNA synthesis (G2). Enucleate merogones, parthenogenetically activated, synthesize histones encoded upon maternal histone messenger RNA. The pattern of protein synthesis changes following fertilization, in part, but not solely, due to the increasing synthesis of histones relative to other proteins. Regulation of histone synthesis and the loading of newly replicated DNA with histones must themselves undergo change at the time of transition from cleavage cycles to cycles more typical of somatic cells.
D000818:Animals; D001345:Autoradiography; D002453:Cell Cycle; D002467:Cell Nucleus / Q000378:metabolism; D004247:DNA / Q000096:biosynthesis*; D004591:Electrophoresis, Polyacrylamide Gel; D004625:Embryo, Nonmammalian / Q000378:metabolism*; D006657:Histones / Q000096:biosynthesis* / Q000302:isolation & purification; D012617:Sea Urchins / Q000378:metabolism
D006657:Histones; D004247:DNA
Dev Biol. 1977 May;57(1):136-49
67977
Cell. 1977 Feb;10(2):237-43
189936
Proc Natl Acad Sci U S A. 1977 Jan;74(1):173-7
264672
Cell Differ. 1977 Mar;5(5-6):283-91
558056
Cell Biol Int Rep. 1977 Jan;1(1):23-30
565255
Proc Natl Acad Sci U S A. 1976 Jun;73(6):1863-7
778847
Eur J Biochem. 1977 Jan;72(2):385-92
837922
Cell. 1976 Sep;9(1):171-8
987854
Cell. 1976 Oct;9(2):311-22
987857
Cell. 1975 Jan;4(1):59-67
1116174
Nature. 1975 Sep 18;257(5523):247-8
1161028
Dev Biol. 1975 Apr;43(2):254-63
1168601
Eur J Biochem. 1975 Aug 15;56(2):335-41
1175627
Dev Biol. 1976 Feb;48(2):327-35
1254085
Proc Natl Acad Sci U S A. 1967 Aug;58(2):681-8
4168359
J Mol Biol. 1974 Sep 15;88(2):263-85
4476799
Proc Natl Acad Sci U S A. 1973 Oct;70(10):2840-4
4517937
Proc Natl Acad Sci U S A. 1973 Sep;70(9):2614-8
4582192
Biochim Biophys Acta. 1973 Feb 4;294(1):481-96
4705997
Biochem Biophys Res Commun. 1973 Jul 17;53(2):515-22
4736817
J Mol Biol. 1973 Oct 5;79(4):681-96
4796595
Nature. 1974 Jan 4;247(5435):36-8
4808938
Dev Biol. 1974 Feb;36(2):286-98
4814569
Eur J Biochem. 1974 Jul 1;46(1):83-8
4850204
J Cell Biol. 1966 Oct;31(1):1-9
4961668
J Mol Biol. 1969 Jun 28;42(3):559-75
4979625
Arch Biochem Biophys. 1972 Feb;148(2):633-41
5063077
Proc Natl Acad Sci U S A. 1967 Nov;58(5):1977-83
5237492
J Mol Biol. 1969 Oct 28;45(2):337-51
5367032
Nature. 1970 Aug 15;227(5259):680-5
5432063
Dev Biol. 1970 Feb;21(1):125-46
5445757
J Mol Biol. 1971 Apr 28;57(2):355-8
5579623
Nature. 1968 Aug 24;219(5156):860-1
5673350
Science. 1969 May 23;164(3882):961-3
5813983
Biochim Biophys Acta. 1969 Aug 20;186(2):349-57
5822837
Dev Biol. 1965 Dec;12(3):520-42
5894666
Dev Biol. 1976 Sep;52(2):310-7
12194440
J Biophys Biochem Cytol. 1961 Feb;9:445-62
13786522
Exp Cell Res. 1959;Suppl 6:227-35
13792619
Exp Cell Res. 1964 Oct;36:53-61
14222747
Proc Natl Acad Sci U S A. 1967 Feb;57(2):409-16
16591485