title: Serotonin and monoamine oxidase in mouse skin: effects of cigarette smoke exposure.
abstract: Mice were exposed to either air or cigarette smoke and the content and uptake of serotonin and activity of monoamine oxidase were determined. Serotonin concentration increased as a function of the frequency of exposure, while serotonin uptake by the skin was maximally increased after two 8 min. exposures. MAO activity for serotonin, but not for tyramine, was decreased by cigarette smoke exposure of more than 8 min.
mesh_terms: D000818:Animals; D008297:Male; D051379:Mice; D008995:Monoamine Oxidase / Q000378:metabolism*; D010947:Plants, Toxic; D012701:Serotonin / Q000378:metabolism*; D012867:Skin / Q000201:enzymology / Q000378:metabolism*; D012907:Smoking; D014026:Nicotiana; D014439:Tyramine / Q000378:metabolism
chemical_list: D012701:Serotonin; D008995:Monoamine Oxidase; D014439:Tyramine