title: The effect of sodium trimetaphosphate (TMP) as a chewing gum additive on caries increments in children.
abstract: A three-year study on school-age children using trimetaphosphate as a chewing gum additive produced significant reductions in proximal surface dental caries increments as compared to an non-chewing gum group. The reductions were 23.3% for the TMP sucrose gum group and 47.6% for the TMP nonsugar group as compared to the no-gum group.
mesh_terms: D000293:Adolescent; D002327:Cariostatic Agents; D002638:Chewing Gum; D002648:Child; D002675:Child, Preschool; D004245:DMF Index; D003731:Dental Caries / Q000209:etiology*; D005503:Food Additives / Q000494:pharmacology*; D006801:Humans; D008353:Mannitol / Q000494:pharmacology; D010710:Phosphates / Q000494:pharmacology*; D011122:Polyphosphates; D013012:Sorbitol / Q000494:pharmacology; D013395:Sucrose / Q000494:pharmacology; D013549:Sweetening Agents / Q000494:pharmacology
chemical_list: D002327:Cariostatic Agents; D002638:Chewing Gum; D005503:Food Additives; D010710:Phosphates; D011122:Polyphosphates; D013549:Sweetening Agents; D008353:Mannitol; D013012:Sorbitol; D013395:Sucrose; C009293:trimetaphosphoric acid