title: Radiation-induced epithelial-submucosal separation: an electron and light microscopical investigation.
abstract: Irradiation injury of the mouse tongue was studied by electron and light microscopy. A specific lesion was found to be the result of edema. Epithelial compensation was seen in the form of proliferation of desmosomes and  hemidesmosomes, elongation of rete ridges, and hypertrophy of cytoplasmic projections from basal cells.
mesh_terms: D000818:Animals; D001485:Basement Membrane / Q000528:radiation effects / Q000648:ultrastructure; D001768:Blister / Q000473:pathology; D003593:Cytoplasm / Q000528:radiation effects / Q000648:ultrastructure; D004820:Epidermolysis Bullosa / Q000473:pathology; D004848:Epithelium / Q000528:radiation effects / Q000648:ultrastructure; D005928:Glossitis / Q000473:pathology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009940:Organoids / Q000528:radiation effects / Q000648:ultrastructure; D014059:Tongue / Q000528:radiation effects* / Q000648:ultrastructure