McArdle's disease--what limit to the age of onset?
A patient with McArdle's disease is reported in whome proximal muscle weakness began in the 7th decade. Other unusual features included the absence of muscle cramps at any stage, asymmetrical wasting of the shoulder girdle muscles and calf hypertrophy. Muscle biopsy revealed a vacuolar myopathy, absent phosphorylase staining and qualitatively low glycogen content.
D000367:Age Factors; D000368:Aged; D006008:Glycogen Storage Disease / Q000473:pathology*; D006012:Glycogen Storage Disease Type V / Q000201:enzymology / Q000473:pathology*; D006801:Humans; D008297:Male; D009132:Muscles / Q000201:enzymology / Q000473:pathology / Q000648:ultrastructure; D006005:Phosphorylases / Q000172:deficiency
D006005:Phosphorylases