title: [Palatinite--a new sugar substitute and its caries prophylactic evaluation].
abstract: By means of programmed feeding experiments on rats, the caries-producing properties of a new sugar substitute Palat-nit were compared with those of other carbohydrates. The cariogenicity of Palatinit was significantly lower than that of sucrose and lactose and roughly comparable to that of L-sorbose. Reference strains of s. mutans are unable to produce extra-cellular polysaccharide or notable amounts of acid from Palatinit. The use of this substance as sugar substitute can be recommended for caries prophylaxis on the basis of these experiments.
mesh_terms: D003731:Dental Caries / Q000517:prevention & control*; D004187:Disaccharides / Q000378:metabolism; D004341:Drug Evaluation; D005947:Glucose / Q000031:analogs & derivatives / Q000378:metabolism; D006801:Humans; D013295:Streptococcus mutans / Q000378:metabolism; D013402:Sugar Alcohols / Q000378:metabolism; D013549:Sweetening Agents / Q000378:metabolism
chemical_list: D004187:Disaccharides; D013402:Sugar Alcohols; D013549:Sweetening Agents; C016640:Palatinit; D005947:Glucose
vernacular_title: Palatinit--ein neuer Zuckeraustauschstoff und seine kariesprophylaktische Beurteilung.