The pathophysiology of renal hypertension.
The increased understanding of the mechanisms leading to production of renal hypertension, and in particular the recognition of the renin-angiotensin-aldosterone axis as an integrated capacity-volume system for the control of arterial blood pressure, now allows a rational approach to the diagnosis and management of patients suffering from this disease. In this brief review some of the experimental evidence behind this rational approach is presented.
D000450:Aldosterone / Q000502:physiology; D000804:Angiotensin II / Q000502:physiology; D000818:Animals; D003250:Constriction; D004195:Disease Models, Animal; D004285:Dogs; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery; D007606:Juxtaglomerular Apparatus / Q000378:metabolism; D051381:Rats; D012077:Renal Artery; D012083:Renin / Q000378:metabolism
D000804:Angiotensin II; D000450:Aldosterone; D012083:Renin