title: Antimicrobial effects of N2 in vitro.
abstract: The antimicrobial effect of the root canal filling material N2 has been studied in vitro. Pulverized as well as intact set N2 inhibited the growth of the mixed bacterial flora of saliva or pure cultures of S. mutants and A. viscosus on blood agar for at least 100 days. Intact set N2 transferred daily to blood agar inoculated with saliva lost its antimicrobial activity after nine transfers. The antimicrobial effect of N2 against S. mutants was found to be bactericidal. N2 also appeared to possess an antimicrobial "vapor effect".
mesh_terms: D000190:Actinomyces / Q000187:drug effects*; D005557:Formaldehyde; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D012463:Saliva / Q000382:microbiology; D013295:Streptococcus mutans / Q000187:drug effects*
chemical_list: D012387:Root Canal Filling Materials; D005557:Formaldehyde