In vitro metabolism of 4-androstene-3,17-dione by human submaxillary gland homogenates.
Tritiated 4-androstene-3,17-dione was incubated with human submaxillary gland homogenates. In 180-minute incubations, human submaxillary gland converted 4-androstene-3,17-dione predominately to testosterone and to a lesser extent, 5alpha-androstane-3alpha,17beta-diol and androsterone.
D000328:Adult; D000368:Aged; D000734:Androstenediols / Q000096:biosynthesis; D000735:Androstenedione / Q000378:metabolism*; D046508:Culture Techniques; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013363:Submandibular Gland / Q000378:metabolism*; D013739:Testosterone / Q000096:biosynthesis
D000734:Androstenediols; D013739:Testosterone; D000735:Androstenedione