title: Urea in the management of advanced malignancies (preliminary report).
abstract: Twenty cases of advanced (Stage III) cancer of the cervix were treated with intratumour injection of 40% urea solution and local application of 50% urea ointment. Sixty percent of these patients had beneficial effect and in 25% of the patients there was minimal response. Patients with multiple secondaries in liver had very good symptomatic relief with oral urea. Urea therapy is a simple, cheap, and safe method of treating advanced stages of cancer, where very little can be done by the accepted lines of treatment such as surgery or radiotherapy. This line of treatment can be practiced even in a consulting room or primary health center.
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy; D001859:Bone Neoplasms / Q000188:drug therapy; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy*; D005260:Female; D005334:Fever / Q000139:chemically induced; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy; D008297:Male; D009362:Neoplasm Metastasis; D012516:Osteosarcoma / Q000188:drug therapy; D010412:Penile Neoplasms / Q000188:drug therapy; D014508:Urea / Q000009:adverse effects / Q000627:therapeutic use*; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy*
chemical_list: D014508:Urea