Levodopa in the treatment of Parkinson's disease.
Levodopa is at present the most effective treatment of Parkinson's disease. Its use in combination with a peripheral decarboxylase inhibitor prolongs the elevation of plasma levels and decreases the incidence of peripheral side effects. Severe psychiatric and neurologic side-effects may necessitate reduction or cessation of the drug.
D001921:Brain / Q000378:metabolism; D006801:Humans; D007980:Levodopa / Q000009:adverse effects / Q000378:metabolism / Q000627:therapeutic use*; D010300:Parkinson Disease / Q000188:drug therapy* / Q000378:metabolism
D007980:Levodopa