Toxic psychosis due to cyproheptadine in a child on hemodialysis: a case report.
In 1971 Simmons et al. presented evidence that children receiving regular dialysis therapy required approximately seventy percent of recommended caloric intake to achieve normal growth. Since that time, pediatric nephrologists and dietitians have strived to meet that requirement. In an effort to attain adequate caloric intake, cyproheptadine, a known appetite stimulant, was prescribed to a child on chronic hemodialysis. The following reports the unexpected complication of toxic psychosis that resulted.
D002648:Child; D003533:Cyproheptadine / Q000009:adverse effects* / Q000627:therapeutic use; D001068:Feeding and Eating Disorders / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D008297:Male; D011605:Psychoses, Substance-Induced / Q000209:etiology*; D006435:Renal Dialysis / Q000009:adverse effects
D003533:Cyproheptadine