title: [Etiopathogenetical, clinical and therapeutic considerations on meningo-encephalic localizations in acute lymphatic leukemias: personal contribution].
abstract: The aetiology, pathogenesis, clinical forms and therapeutic attempts carried out in connection with the central nervous system localizations in acute lymphoblastic leukaemia, on the basis of an extensive review of the literature and of personal experience are examined. The particular role which central nervous system leukaemia plays on the subsequent clinical course of the disease is stressed and the efforts made, both prophylactically and therapeutically, in order to decrease the incidence of this complication, which invariably has a deteriorating influence of the progress of the disease are described.
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001344:Autopsy; D002648:Child; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008590:Meningoencephalitis / Q000209:etiology*
chemical_list: D000305:Adrenal Cortex Hormones; D000970:Antineoplastic Agents
vernacular_title: Considerazioni eziopatogenetiche, cliniche e terapeutiche sulle localizzazioni meningo-encefaliche nelle leucemie linfatiche acute: contributo personale.