A saliva substitute for use by xerostomic patients undergoing radiotherapy to the head and neck.
A saliva substitute has been developed for use in veteran patients, primarity those undergoing radiotherapy for malignancy of the head and neck. The viscosity of the solution is adjusted to simulate that of whole saliva, and the electrolyte levels are similarly set. Fluoride is included at the level of 5.0 p.p.m. in an effort to enhance the mineralizing capacity of this preparation which is high in calcium and phosphate.
D002712:Chlorides / Q000627:therapeutic use; D003743:Dental Enamel / Q000502:physiology; D005459:Fluorides / Q000627:therapeutic use; D006244:Hardness; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D010758:Phosphorus / Q000627:therapeutic use; D011188:Potassium / Q000627:therapeutic use; D012463:Saliva; D012964:Sodium / Q000627:therapeutic use; D012996:Solutions; D014987:Xerostomia / Q000628:therapy*
D002712:Chlorides; D012996:Solutions; D010758:Phosphorus; D012964:Sodium; D005459:Fluorides; D011188:Potassium