Blood and urinary 18F pharmacokinetics following parenteral administration in the rat.
Blood and urinary excretion time courses of 18F administered parenterally to rats were monitored for two hours. The intraperitoneal, subcutaneous, and intravenous routes gave kinetically indistinguishable results after ten minutes following the dose. The blood time course during the first hour following intramuscular dosing showed a relative constancy and suggested a delayed absorption time.
D000818:Animals; D005260:Female; D005461:Fluorine / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism* / Q000652:urine; D007273:Injections, Intramuscular; D007274:Injections, Intraperitoneal; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D011868:Radioisotopes / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism* / Q000652:urine; D051381:Rats
D011868:Radioisotopes; D005461:Fluorine