An assessment of vulval lichen sclerosus.
Vulval lichen sclerosus (L.S.) has been assessed clinically, colposcopically, and histologically to ascertain the suitability of including this condition in the nomenclature proposed by the International Society for the Study of Vulval Disease (I.S.S.V.D). In many cases the macroscopic appearance of lichen sclerosus is characteristic, but this is not always the case. Histologically, the appearances of the dermal hyaline change, the reduction in the length and the number of rete pegs, to a lesser extent thinning of the dermis and sometimes thinning of the epidermis are characteristics. The presence of dermal inflammatory cells and changes in the thickness of the keratin layer are, however, much more variable. Exact measurements of the various layers of the vulval skin are not necessary in the routine assessment of lichen sclerosus. The present study justifies the inclusion of lichen sclerosus on histological criteria in the I.S.S.V.D.'s nomenclature.
D005260:Female; D006801:Humans; D007391:International Cooperation; D012598:Sclerosis; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000145:classification* / Q000175:diagnosis; D009626:Terminology as Topic; D014844:Vulva / Q000473:pathology; D014845:Vulvar Diseases / Q000145:classification* / Q000175:diagnosis