Interferon therapy in neoplastic disease. A preliminary report.
The treatment of 10 patients having neoplastic disease with exogenous i.m. interferon therapy is described. The interferon given is partially purified interferon produced from human leukocytes. Sendai virus is used as interferon inductor. The patients reported in this paper have been on treatment for periods of 2-28 months. Apart from initial periods of fever, no side-effects have been recorded. Patients suffering from bladder papillomas have shown partial regression after a few months of therapy. The other cases treated are too few to warrant any conclusions, but the therapy does seem to have been beneficial.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage; D001859:Bone Neoplasms / Q000188:drug therapy; D002648:Child; D005260:Female; D006801:Humans; D007372:Interferons / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000188:drug therapy* / Q000601:surgery; D012516:Osteosarcoma / Q000188:drug therapy / Q000628:therapy; D010212:Papilloma / Q000601:surgery / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000601:surgery; D014594:Uterine Neoplasms / Q000532:radiotherapy / Q000628:therapy
D000970:Antineoplastic Agents; D007372:Interferons