title: Haemophilia.
abstract: The clinical and haematological features of haemophilia are reviewed and the historical aspects, pathogenesis and genetics are discussed. The problems associated with management, such as factor replacement, home therapy, physiotherapy, surgical intervention and the presence of inhibitors, are fully described. Finally, mention is made of the psychological problems of haemophiliacs and of the help given by the South African Haemophilia Foundation.
mesh_terms: D000906:Antibodies; D001803:Blood Transfusion; D002648:Child; D005169:Factor VIII / Q000276:immunology / Q000627:therapeutic use; D005260:Female; D005808:Genes, Recessive; D006467:Hemophilia A / Q000150:complications / Q000235:genetics / Q000628:therapy; D006701:Home Nursing; D006801:Humans; D007223:Infant; D008297:Male; D011183:Postoperative Complications / Q000517:prevention & control; D014842:von Willebrand Diseases
chemical_list: D000906:Antibodies; D005169:Factor VIII