title: [Immunologic development disorders and disease incidence].
abstract: Interference with any organ system during development leads to permanent damage. Severe disease or starvation during the first four months of extrauterine life lead to a persistent deficiency of cell mediated immunity, which changes the life expectancy and later disease patterns in population groups. Severe intercurrent disease, starvation or trauma later in life lower cell mediated immunity only temporarily.
mesh_terms: D000486:Allergy and Immunology; D000818:Animals; D002657:Child Development; D005260:Female; D005315:Fetal Diseases / Q000150:complications; D006801:Humans; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000209:etiology; D007223:Infant; D007231:Infant, Newborn; D002955:Leucovorin / Q000172:deficiency; D008297:Male; D051379:Mice; D009017:Morbidity; D009748:Nutrition Disorders / Q000150:complications; D011247:Pregnancy; D013217:Starvation / Q000150:complications; D013950:Thymus Gland / Q000378:metabolism
chemical_list: D002955:Leucovorin
vernacular_title: Immunologische Entwicklungsstörungen und Krankheitshäufigkeit.