The distinctive features of acute monocytic leukemia.
Acute monocytic leukemia is an uncommon form of acute leukemia. Distinctive clinical features include gingival hypertrophy, lymphoadenopathy, coagulation disorders, and lysozymuria. Blast cell morphology and cytochemistry are diagnostic. Receptors for the Fc fragment of IgG have been demonstrated on the basis of a few cases. The drug VP 16-213 has been shown to be very effective in treatment of untreated and previously treated patients.
D001778:Blood Coagulation Disorders / Q000209:etiology; D002467:Cell Nucleus / Q000648:ultrastructure; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D004950:Esterases; D005047:Etoposide / Q000627:therapeutic use; D005886:Gingival Hypertrophy / Q000209:etiology; D006651:Histocytochemistry; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000175:diagnosis* / Q000188:drug therapy; D008198:Lymph Nodes / Q000473:pathology; D009000:Monocytes / Q000648:ultrastructure; D009113:Muramidase / Q000097:blood; D011239:Prednisolone / Q000627:therapeutic use; D014747:Vinblastine / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine; D014747:Vinblastine; D005047:Etoposide; D011239:Prednisolone; D004950:Esterases; D009113:Muramidase