title: Reactivity of HLA typing sera against cultured lymphoblastoid cell lines and purified peripheral B and T cells from the same original donors.
abstract: Anomalous cytotoxicity reactions are observed in some HLA typing sera when cultured lymphoid cells are used as targets. These extra reactions are also detected when the purified B cells from the original donors of the cell lines are used. This observation strongly indicates that these extra reactions are directed to the B cell alloantigens which are normally expressed on B cells of the original donor.
mesh_terms: D001402:B-Lymphocytes / Q000276:immunology*; D002471:Cell Transformation, Neoplastic; D003601:Cytotoxicity Tests, Immunologic; D006680:HLA Antigens; D006801:Humans; D007106:Immune Sera; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D006680:HLA Antigens; D007106:Immune Sera