Antibacterial effect of salivary peroxidases on a cariogenic strain of Streptococcus mutans.
The antibacterial effect of purified human salivary lactoperoxidase on a cariogenic strain of Streptococcus mutans was demonstrated while another oral peroxidase, probably of leukocytic origin, did not affect the growth. Lactoperoxidase was rapidly adsorbed by bacterial cells indicating the necessity of the contact between the enzyme and the cells before inhibition.
D000327:Adsorption; D000900:Anti-Bacterial Agents; D003731:Dental Caries / Q000382:microbiology; D006861:Hydrogen Peroxide / Q000494:pharmacology; D007784:Lactoperoxidase / Q000494:pharmacology; D010544:Peroxidases / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology*; D012463:Saliva / Q000201:enzymology*; D013295:Streptococcus mutans / Q000187:drug effects* / Q000378:metabolism
D000900:Anti-Bacterial Agents; D006861:Hydrogen Peroxide; D007784:Lactoperoxidase; D010544:Peroxidases