title: Anisotropic molecular motion on cell surfaces.
abstract: Photobleaching in a two-dimensional periodic pattern has been used to characterize the motion of succinylconcanavalin A receptors on the surfaces of mouse fibroblasts. These receptors were found to exhibit anisotropic two-dimensional diffusion in adherent cells having parallel stress fibers. Diffusion coefficients of the order of 10(-11) cm2/sec and 10(-12) cm2/sec were measured for diffusive motions parallel and perpendicular to these fibers. The determination of the anisotropic motion used a two-dimensional Fourier analysis. A study was made of the effect of changes in cell shape on the photobleach pattern.
mesh_terms: D000818:Animals; D002465:Cell Movement; D004058:Diffusion; D005347:Fibroblasts; D005583:Fourier Analysis; D008560:Membrane Fluidity; D051379:Mice; D010777:Photochemistry; D011952:Receptors, Concanavalin A / Q000378:metabolism*; D013696:Temperature
chemical_list: D011952:Receptors, Concanavalin A