Effect of fluoride topical solutions on enamel demineralization by lactate buffers and Streptococcus mutans in vitro.
Applications of APF and NaF solutions to extracted human teeth reduced the extent of enamel subsurface demineralization induced by colonization of S. mutans but were ineffective against demineralization by acid lactate buffers. It is concluded that the CaF2 formed on the tooth surface during the treatment is responsible for the protection observed.
D000149:Acidulated Phosphate Fluoride / Q000494:pharmacology; D000268:Adhesiveness; D002021:Buffers; D002124:Calcium Fluoride / Q000494:pharmacology; D003743:Dental Enamel / Q000378:metabolism; D003747:Dental Enamel Solubility / Q000187:drug effects*; D005460:Fluorides, Topical / Q000494:pharmacology*; D006801:Humans; D007773:Lactates / Q000494:pharmacology*; D012969:Sodium Fluoride / Q000494:pharmacology; D013295:Streptococcus mutans / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D013997:Time Factors
D002021:Buffers; D005460:Fluorides, Topical; D007773:Lactates; D000149:Acidulated Phosphate Fluoride; D012969:Sodium Fluoride; D002124:Calcium Fluoride