Accidental intrathecal administration of vincristine.
Vincristine is a chemotherapeutic agent used in the treatment of various neoplastic diseases. Its neurotoxicity after therapeutic and pharmacologic doses has been well documented. We report a case of accidental intrathecal administration of vincristine in order to describe the complications seen, discuss possible means of therapeutic intervention, and serve as a reminder that preventive measures are mandatory to avoid such accidents in the future.
D002675:Child, Preschool; D006801:Humans; D007278:Injections, Spinal; D007945:Leukemia, Lymphoid / Q000188:drug therapy; D008508:Medication Errors; D009422:Nervous System Diseases / Q000139:chemically induced; D014750:Vincristine / Q000008:administration & dosage* / Q000009:adverse effects
D014750:Vincristine