title: Heart rate changes caused by enflurane and halothane anaesthesia in man.
abstract: Changes in heart rate and arterial pressure caused by enflurane and halothane anaesthesia were investigated in patients premedicated with diazepam and scopolamine. Enflurane caused a significant (12%) increase in heart rate and depression of arterial pressure (23%). Halothane depressed heart rate significantly (14%), whereas arterial pressure was unaffected. The authors conclude that enflurane possesses a positive chronotropic effect.
mesh_terms: D000328:Adult; D000368:Aged; D000769:Anesthesia, Inhalation; D001794:Blood Pressure / Q000187:drug effects; D003975:Diazepam; D004737:Enflurane / Q000494:pharmacology*; D005260:Female; D006221:Halothane / Q000494:pharmacology*; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male; D008738:Methyl Ethers / Q000494:pharmacology*; D008875:Middle Aged; D010313:Partial Pressure; D011229:Preanesthetic Medication; D012601:Scopolamine
chemical_list: D008738:Methyl Ethers; D004737:Enflurane; D012601:Scopolamine; D003975:Diazepam; D006221:Halothane