Successful treatment of invasive pulmonary aspergillosis in the immunocompromised host.
We have reported the successful treatment of a patient with acute leukemia complicated by pulmonary aspergillosis, a commonly fatal situation. Specific diagnosis was obtained easily by transbronchial lung biopsy. Our therapeutic approach included aggressive treatment of both the underlying malignant process and the aspergillosis with a combination of amphotericin B and rifampin.
D000666:Amphotericin B / Q000627:therapeutic use*; D001228:Aspergillosis / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D008172:Lung Diseases, Fungal / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012293:Rifampin / Q000627:therapeutic use*
D000666:Amphotericin B; D012293:Rifampin