Two new concepts that might lead to a wearable artificial kidney.
A wearable artificial kidney involving two novel components is proposed. It consists of a turbulent flow ultrafiltering shunt, which supplies 20 liters of ultrafiltrate per day to a disposable activated charcoal cartridge (where creatinine, uric acid, and other tightly bound solutes are adsorbed) and then to an artificial loop of Henle (where the urea is concentrated into 2 liters of ultrafiltrate per day and discarded) from which 18 liters of cleansed, rewarmed ultrafiltrate containing 87% of the glucose is returned to the patient.
D001698:Biomedical Engineering; D006801:Humans; D007688:Kidneys, Artificial / Q000295:instrumentation*; D014462:Ultrafiltration / Q000295:instrumentation / Q000379:methods