title: [Influence of inflammation on keratinocytes of the palatal mucosa of guinea pigs].
abstract: The palatal mucosa of the guinea pig contained in the normal state a certain number of binucleated cells. Injections of substances inducing inflammation (carrageenan, calcium pyrophosphate dihydrate, monosodium urate) were made in order to produce an inflammatory reaction in the palatal mucosa of young male and adult guinea pigs. The percentage of binucleated epithelial cells was estimated at different time intervals after injections. For the three injected substances, a significant increase of the binucleated epithelial cells was noted in the palatal injected mucosa, when compared with a healthy mucosa or a mucosa having been injected with saline.
mesh_terms: D000818:Animals; D002131:Calcium Pyrophosphate / Q000494:pharmacology; D002351:Carrageenan / Q000494:pharmacology; D002452:Cell Count; D002467:Cell Nucleus / Q000648:ultrastructure; D004848:Epithelium / Q000187:drug effects / Q000473:pathology; D006168:Guinea Pigs; D007633:Keratins; D008297:Male; D009061:Mouth Mucosa / Q000187:drug effects / Q000473:pathology*; D010159:Palate; D013280:Stomatitis / Q000473:pathology*; D014527:Uric Acid / Q000494:pharmacology
chemical_list: D014527:Uric Acid; D007633:Keratins; D002351:Carrageenan; D002131:Calcium Pyrophosphate
vernacular_title: Influence de l'inflammation sur les kératinocytes de la muqueuse palatine du cobaye.