[Peripheral microthrombotic purpura associated with acute promyelocytic leukemia in pregnancy. A light and electron microscopic study].
A case is presented of a pregnant patient in the 28th week of gestation with promyelocytic leukemia and an unusual thrombohemorrhagic skin lesion. Ultrastructural examination revealed a microthrombotic purpura. Reduced coagulation factors increased during heparin treatment. The exacerbation of disseminated intravascular coagulation is explained by a hypercoagulable state in pregnancy in association with the as yet unknown etiology of "promyelocytic fibrinopathic leukemia".
D000328:Adult; D002196:Capillaries / Q000473:pathology / Q000648:ultrastructure; D004211:Disseminated Intravascular Coagulation / Q000473:pathology; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications* / Q000473:pathology / Q000648:ultrastructure; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000473:pathology; D011262:Pregnancy Trimester, Second; D011697:Purpura, Thrombotic Thrombocytopenic / Q000150:complications* / Q000473:pathology
Periphere mikrothrombotische Purpura be i akuter promyelocytischer Leukämie in der Schwangerschaft. Eine licht- und elektronenmikroskopische Untersuchung.