[T- and B-lymphocytes in lymphogranulomatosis].
The authors report the results of the complex investigation of T-and B-lymphocytes in peripheral blood and functional features of T-cells in the reaction of blasttransformation with PHA in 27 patients with lymphogranulomatosis and in 30 healthy individuals. Generalized forms of lymphogranulomatosis of stage III-IV (in 21 of 27 patients) were predominating. All patients showed an active phase of the lesion. T-system immunity was found to be suppressed, that was manifested in reduced T-cells number, a decreased lymphocytes RBT to PHA per one or two dilutions. It is supposed that the observed T-lymphocytes disorders is one of the causes of the impairment of cell immunity reactions, found in vivo in patients with lymphogranulomatosis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology*; D005260:Female; D006689:Hodgkin Disease / Q000097:blood / Q000276:immunology* / Q000473:pathology; D006801:Humans; D066298:In Vitro Techniques; D037102:Lectins / Q000494:pharmacology; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology* / Q000473:pathology
D037102:Lectins
T- i B-limfotsity u bol'nykh limfogranulematozom.