T lymphocytes in children with allergic respiratory disease.
The role of T lymphocytes in atopic disease is of considerable importance because animal studies indicate that cells of this lymphoid series may influence reaginic antibody response. T lymphocyte subpopulations were studied in a group of 76 children with allergic respiratory disease. There was no statistical difference between atopic children with asthma and those with allergic rhinitis as compared with an age-matched control population of 20 non-atopic children in terms of levels of active T lymphocytes or total T lymphocytes. The results of this study do not support the concept of a T cell immunodeficiency in children with allergic respiratory disease.
D002648:Child; D002675:Child, Preschool; D006801:Humans; D007958:Leukocyte Count; D012130:Respiratory Hypersensitivity / Q000097:blood / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*