Hemophilus influenzae pneumonia in adults.
Hemophilus influenzae pneumonia was diagnosed in 41 adult patients based on cultures of blood, pleural fluid or transtracheal aspirate. Bacteremia occurred in all age groups, but was most frequent in patients over the age of 50 years with severe underlying pulmonary disease. Chest films usually demonstrated multisegmental or multilobar infiltrates without evidence of cavitation. Pleural involvement was evident in half of the patients, although empyema occurred infrequently. Mortality was almost always associated with serious underlying diseases and bacteremia. Encapsulated strains of H. influenzae (usually type B) were identified in 18 of 22 (82 per cent) patients. The use of transtracheal aspirations and the adoption of routine subculturing of blood cultures on chocolate agar appear to be important factors in our increased recognition of this disease.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006192:Haemophilus Infections / Q000175:diagnosis* / Q000401:mortality; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010996:Pleural Effusion / Q000382:microbiology; D011014:Pneumonia / Q000175:diagnosis / Q000382:microbiology*; D018805:Sepsis / Q000382:microbiology; D013183:Sputum / Q000382:microbiology; D014132:Trachea / Q000382:microbiology