title: Relevance of circulating immune complexes in childhood acute lymphoblastic leukaemia.
abstract: Circulating immune complexes have been measured using the (125I)C1q binding test in 216 sera from 135 children with acute lymphoblastic leukaemia. Increased circulating immune complexes were detectable in 10.7% of the sera and 10.4% of the children. There was no correlation between the presence of circulating immune complexes and prognosis, but a strong correlation with a history of recent infection.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000912:Antibodies, Neoplasm; D000936:Antigen-Antibody Complex; D000951:Antigens, Neoplasm; D002648:Child; D002675:Child, Preschool; D003172:Complement C1; D003168:Complement Fixation Tests; D005260:Female; D006801:Humans; D007223:Infant; D007239:Infections / Q000150:complications / Q000276:immunology; D007945:Leukemia, Lymphoid / Q000150:complications / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011379:Prognosis
chemical_list: D000912:Antibodies, Neoplasm; D000936:Antigen-Antibody Complex; D000951:Antigens, Neoplasm; D003172:Complement C1