Heart rate changes caused by enflurane and halothane anaesthesia in man.
Changes in heart rate and arterial pressure caused by enflurane and halothane anaesthesia were investigated in patients premedicated with diazepam and scopolamine. Enflurane caused a significant (12%) increase in heart rate and depression of arterial pressure (23%). Halothane depressed heart rate significantly (14%), whereas arterial pressure was unaffected. The authors conclude that enflurane possesses a positive chronotropic effect.
D000328:Adult; D000368:Aged; D000769:Anesthesia, Inhalation; D001794:Blood Pressure / Q000187:drug effects; D003975:Diazepam; D004737:Enflurane / Q000494:pharmacology*; D005260:Female; D006221:Halothane / Q000494:pharmacology*; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male; D008738:Methyl Ethers / Q000494:pharmacology*; D008875:Middle Aged; D010313:Partial Pressure; D011229:Preanesthetic Medication; D012601:Scopolamine
D008738:Methyl Ethers; D004737:Enflurane; D012601:Scopolamine; D003975:Diazepam; D006221:Halothane