title: [Adenyl cyclase activity of human blood platelets in various blood diseases].
abstract: Adenyl cyclase activity was estimated in blood platelets of healthy persons and of patients with myeloleukosis, osteomyelofibrosis and with Glanzmann's thrombasthenia. Six-fold decrease in the adenyl cyclase activity from the platelets was observed in chronic myeloleukosis. The enzymatic activity in platelets was similar to normal level in osteomyelofibrosis and Glanzmann's thrombasthenia.
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism*; D001792:Blood Platelets / Q000201:enzymology*; D006801:Humans; D066298:In Vitro Techniques; D007951:Leukemia, Myeloid / Q000097:blood*; D055728:Primary Myelofibrosis / Q000097:blood*; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000235:genetics*; D013577:Syndrome
chemical_list: D000262:Adenylyl Cyclases
vernacular_title: Aktivnost' adeniltsiklazy krovianykh plastinok cheloveka pri nekotorykh zabolevaniiakh sistemy krovi.