title: Response of two rodents, Mastomys natalensis and Mystromys albicaudatus, to the pancreatic carcinogen azaserine.
abstract: The response of two rodents to azaserine carcinogenicity for the pancreas was evaluated. Mystromys albicaudatus was not responsive; however, Mastomys natalensis developed large numbers of atypical acinar cell nodules and several adenomas in a 6-month study. Mastomys is the most responsive of several animals in which azaserine has been studied as a pancreatic carcinogen.
mesh_terms: D000236:Adenoma / Q000139:chemically induced / Q000473:pathology; D000818:Animals; D001377:Azaserine / Q000633:toxicity*; D009374:Neoplasms, Experimental / Q000139:chemically induced; D010190:Pancreatic Neoplasms / Q000139:chemically induced* / Q000473:pathology; D011230:Precancerous Conditions / Q000139:chemically induced / Q000473:pathology; D012377:Rodentia
chemical_list: D001377:Azaserine