Posterior amorphous corneal dystrophy.
A family of ten individuals aged 18 months to 75 years had biomicroscopic findings consisting of large, amorphous, sheet-like opacifications of the posterior stroma and Descemet's membrane, and alterations of the endothelium. A uniform thinning of the cornea was present. These findings do not conform to previously described corneal dystrophies. The condition appears minimally progressive and the three-generation pedigree indicated an autosomal-dominant inheritance pattern.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003317:Corneal Dystrophies, Hereditary / Q000235:genetics* / Q000473:pathology; D003886:Descemet Membrane / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010375:Pedigree