Characterization of glycogen in selected tissues of turkey poults with spontaneous round heart disease and furazolidone-induced cardiomyopathy.
Furazolidone (FZ) at 700 ppm was added to feed mixtures fed turkey poults 2--5 weeks after hatching to induce acute experimental cardiomyopathy. Poults in the control pen received the same ration but without FZ. From EKG data obtained at weekly intervals, poults were selected for sacrifice at 5 and 10 weeks of age. Poults were sacrificed by cervical dislocation and appropriate samples of tissue from the left ventricle, liver, pectoralis and tibialis cranialis muscles were removed for glycogen assays. Character of glycogen, as determined by percent of branching and number of glucose units per segment, was not significantly altered in poults with spontaneous round heart disease or FZ-induced cardiomyopathy. This suggests that the glycogen accumulation noted in these conditions most closely resembles type II glycogenosis.
D000818:Animals; D009202:Cardiomyopathies / Q000139:chemically induced / Q000378:metabolism / Q000662:veterinary*; D005664:Furazolidone; D005947:Glucose / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism*; D006008:Glycogen Storage Disease / Q000378:metabolism*; D006009:Glycogen Storage Disease Type II / Q000378:metabolism*; D006331:Heart Diseases / Q000378:metabolism / Q000662:veterinary*; D008099:Liver / Q000378:metabolism; D008112:Liver Glycogen / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D010369:Pectoralis Muscles / Q000378:metabolism; D011201:Poultry Diseases / Q000378:metabolism*; D014422:Turkeys
D008112:Liver Glycogen; D005664:Furazolidone; D006003:Glycogen; D005947:Glucose