Study of some erythrocytic enzymes in extracorpuscular hemolytic anemias.
Investigations on the activity of three erythrocytic enzymes i.e., glucose-6-phosphate dehydrogenase (G-6-PDH), catalase and lactate dehydrogenase (LDH), in 20 patients with extracorpuscular hemolytic anemias of various origins showed a general tendency to decrease of G-6-PDH and catalase, with a concomitant increase in LDH. These results are interpreted as due to metabolic disturbances induced by hemolysis in the erythroblastic series and/or to possible perturbations specific for each type of anemia.
D000293:Adolescent; D000328:Adult; D000743:Anemia, Hemolytic / Q000097:blood*; D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood; D002374:Catalase / Q000097:blood*; D003095:Collagen Diseases / Q000097:blood; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000097:blood*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D007945:Leukemia, Lymphoid / Q000097:blood; D008223:Lymphoma / Q000097:blood; D008297:Male; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000097:blood
D007770:L-Lactate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D002374:Catalase