title: Ocular melanomas: formaldehyde-induced fluorescence in relation to mortality.
abstract: Some ocular malignant melanomas contain enough cysteinyldopa to make them fluorescent when treated with formaldehyde. In 32 ocular malignant melanomas, such fluorescence was seen in 19 cases, which had a slightly, but not significantly, worse prognosis than the 13 cases with no fluorescence. The mixed type of malignant melanoma showed fluorescence significantly more often than the B type. Fluorescence histochemistry thus gives a biochemical classification of the tumor, but not a malignancy prognosis.
mesh_terms: D000328:Adult; D000368:Aged; D005134:Eye Neoplasms / Q000175:diagnosis* / Q000401:mortality; D005260:Female; D005453:Fluorescence; D005557:Formaldehyde; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000401:mortality; D008875:Middle Aged; D011379:Prognosis; D013548:Sweden
chemical_list: D005557:Formaldehyde