title: Fluoride treatment and microhardness of dentin.
abstract: Effects of various fluoride treatments on the microhardness of human dentin were determined. Treatment with acidulated phosphate-fluoride at pH 3.0 induced a significant (p less than .05) softening when compared to treatment with water. APF at pH 4.0 did not bring about a significant change. Response to treatment with 0.4% SnF2 did not differ significantly from water treatment. Sequential treatment with APF (pH 4.0) followed by SnF2 produced significant (p less than .05) hardening of dentin. This hardening with APF-SnF2 differed at a high level of significance (p less than .001) from the softening produced by the pH 3.0 APF. A similarly significant difference was found between this single APF treatment and the single SnF2 treatment. When hardening of exposed dentin surfaces is desired, the sequential treatment method should be employed.
mesh_terms: D000149:Acidulated Phosphate Fluoride / Q000008:administration & dosage / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D003804:Dentin / Q000187:drug effects*; D003808:Dentin Solubility / Q000187:drug effects*; D005460:Fluorides, Topical / Q000494:pharmacology*; D006244:Hardness; D006801:Humans; D014002:Tin Fluorides / Q000008:administration & dosage / Q000494:pharmacology; D014867:Water
chemical_list: D005460:Fluorides, Topical; D014002:Tin Fluorides; D014867:Water; D000149:Acidulated Phosphate Fluoride