title: Fluoride uptake and caries rate in hamster molars after topical fluoride application followed by acidulation.
abstract: Daily topical application of 2% NaF on hamster molars for 4 days in vivo, followed by acidulation (grapefruit beverage, pH 3.3) resulted in a lower caries rate than NaF followed by water application. Fluoride uptake was somewhat higher, but not significantly so in the acidulated group.
mesh_terms: D000818:Animals; D001628:Beverages; D002957:Citrus; D006224:Cricetinae; D003731:Dental Caries / Q000209:etiology*; D004037:Diet, Cariogenic; D005460:Fluorides, Topical / Q000008:administration & dosage / Q000378:metabolism*; D008647:Mesocricetus; D008963:Molar; D012969:Sodium Fluoride / Q000008:administration & dosage; D014867:Water / Q000494:pharmacology
chemical_list: D005460:Fluorides, Topical; D014867:Water; D012969:Sodium Fluoride