Diet-induced arteriopathies in the rabbit aorta and oral vasculature.
Advanced atherosclerosis in the form of fibro-fatty intimal plaques has been produced in the rabbit aorta and oral vasculature (labial, lingual, gingival, palatal, periodontal and alveolar arteries) by dietary means. The animals were fed a hypercholesteremic diet and a normocholesteremic diet on alternate months for two years. In the aorta and in many of the oral vessels, the formation of the intimal atheromas was paralleled by a degeneration of the tunica media. The lingual arteries rivaled the aorta and coronary arteries in vulnerability to the diet-induced arteriopathies.
D000818:Animals; D001011:Aorta / Q000473:pathology; D001018:Aortic Diseases / Q000209:etiology* / Q000473:pathology; D001158:Arteries / Q000473:pathology; D001161:Arteriosclerosis / Q000209:etiology* / Q000473:pathology; D002784:Cholesterol / Q000097:blood; D004036:Diet, Atherogenic; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D008297:Male; D009055:Mouth / Q000098:blood supply*; D011817:Rabbits
D002784:Cholesterol