[Role of immune RNA in the interaction of T- AND B-lymphocytes].
"Immune" RNA preparations were obtained from the total population and also from the T- and B-lymphocytes of the spleens of the QBA line. Intact bone marrow cells or splenic cells activated with antigen served as target cells for the "immune" RNA. Investigations were carried out in the system of syngenic transfer. To study the target cells in the activated population of the spleen elimination of T-or B-lymphocytes was realized immediately after the incubation of the suspension of the splenic cells with the RNA preparations with the aid of anti-theta-or anti-B-antilymphocytic sera. T-lymphocytes served as the source of the biologically active RNA in the total preparation. B-lymphocytes of the spleen and the bone marrow served as target cells for the RNA of the cells of thymus origin. However, to detect the inducing action of the RNA simultaneous presence in the population of T- and B-lymphocytes is necessary.
D000818:Animals; D000917:Antibody Formation; D000961:Antilymphocyte Serum / Q000494:pharmacology; D001402:B-Lymphocytes / Q000032:analysis / Q000276:immunology*; D007106:Immune Sera / Q000494:pharmacology; D051379:Mice; D008808:Mice, Inbred CBA; D012313:RNA / Q000494:pharmacology / Q000502:physiology*; D013154:Spleen / Q000032:analysis; D013601:T-Lymphocytes / Q000032:analysis / Q000276:immunology*
D000961:Antilymphocyte Serum; D007106:Immune Sera; D012313:RNA
Znachenie immunnoĭ RNK vo vzaimodeĭstvii T- i B-limfotsitov