title: The antimicrobial effect of fluorides (acidulated phosphate, sodium and stannous) on Actinomyces viscosus.
abstract: The effect of three commercially prepared fluoride compounds (acidulated phosphate fluoride 1.23% F-, stannous fluoride 0.4%, and sodium fluoride 0.05%) diluted to various concentrations with brain heart infusion broth, on the growth of five strains of Actinomyces viscosus following 1 and 24 hours' exposure to the fluorides was studied. Results demonstrated that SnF2 was the most effective growth inhibitor of the organisms at 500 ppm F- after 1 hour and at 100 ppm F- after 24 hours' exposure. APF and NaF were not effective within a 1 hour exposure period, but did suppress growth of the organisms at 200 ppm in the cultures exposed for 24 hours.
mesh_terms: D000149:Acidulated Phosphate Fluoride / Q000494:pharmacology*; D000190:Actinomyces / Q000187:drug effects*; D000900:Anti-Bacterial Agents; D005459:Fluorides / Q000494:pharmacology*; D005460:Fluorides, Topical / Q000494:pharmacology; D012969:Sodium Fluoride / Q000494:pharmacology*; D013997:Time Factors; D014002:Tin Fluorides / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D005460:Fluorides, Topical; D014002:Tin Fluorides; D000149:Acidulated Phosphate Fluoride; D012969:Sodium Fluoride; D005459:Fluorides