Hypertrophic osteoarthropathy in association with pulmonary metastasis from osteogenic sacroma.
Hypertrophic osteoarthropathy in children is rare, especially when it is associated with lung metastsis. The patient reported herein had metastic osteogenic sarcoma and failed to respond to chemotherapy or thoractomy. There are several theories as to the pathogenesis of osteoarthropathy, but none is totally convincing. Vagotomy or transection of intercostal nerves has been advocated to relieve the symptoms of osteoarthropathy.
D002648:Child; D005266:Femoral Neoplasms / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology; D008297:Male; D009362:Neoplasm Metastasis; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000209:etiology*; D012516:Osteosarcoma / Q000473:pathology*