title: Inhibition of DNA synthesis in concanavalin A stimulated rat lymph node cells by serum from arthritic rats.
abstract: Serum from adjuvant arthritic rats inhibits the mitogenic response of rat lymph node cells to concanavalin A, leaving unaffected the response to phytohemagglutinin. This activity is already evident 4 days after adjuvant administration and persists for at least 28 days.
mesh_terms: D000818:Animals; D001168:Arthritis / Q000097:blood*; D001169:Arthritis, Experimental / Q000097:blood*; D003208:Concanavalin A / Q000494:pharmacology*; D004247:DNA / Q000096:biosynthesis*; D005260:Female; D008198:Lymph Nodes / Q000378:metabolism*; D008214:Lymphocytes / Q000378:metabolism*; D051381:Rats; D011917:Rats, Inbred Lew; D013936:Thymidine / Q000378:metabolism
chemical_list: D003208:Concanavalin A; D004247:DNA; D013936:Thymidine