title: [Intracerebral calcifications associated with intrathecal methotrexate therapy in acute lymphocytic leukemia (author's transl)].
abstract: A case of a child with acute lymphocytic Leukemia is reported. The roentgenograms of the skull show intracerebral "railroad-track-like" calcifications mimicking those seen in Sturge-Weber syndrome. These calcifications are described and their etiology is discussed. The frequency of such observations in cases of acute lymphocytic leukemia with CNS-treatment is increasing.
mesh_terms: D001927:Brain Diseases / Q000139:chemically induced*; D002114:Calcinosis / Q000139:chemically induced*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007945:Leukemia, Lymphoid / Q000150:complications / Q000188:drug therapy*; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D008727:Methotrexate
vernacular_title: Methotrexatbedingte intrazerebrale Verkalkung bei Leukämie.