title: [Acute myelogenous leukemia 11 years after successful treatment of Hodgkin's disease. A contribution to the problem of secondary tumors].
abstract: Acute myelogenous leukemia 11 years after successful treatment of Hodgkin's disease: A contribution to the problem of second malignancies. The occurence of a therapy resistant acute myelogenous leukemia 11 years after successful treatment (operation, radiotherapy, polychemotherapy) of Hodgkin's disease is described. While this second malignancy was rarely seen in the era of minimal or no therapy of Hodgkin's disease, it is nowadays described more often. The possible causes of this second malignant tumor are discussed. Although modern therapy of Hodgkin's disease should not be abandoned from fear of second malignancies, any change in primary treatment must consider not only acute toxicity but also the occurence of late second malignant tumors. Long term follow-up of all patients treated with radiotherapy and/or polychemotherapy is necessary.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D004351:Drug Resistance; D006689:Hodgkin Disease / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D008297:Male; D009378:Neoplasms, Multiple Primary
vernacular_title: Akute myeloische Leukämie 11 Jahre nach erfolgreicher Behandlung eines Morbus Hodgkin.