Generation of cytotoxic T lymphocytes against Ly alloantigen.
Cytotoxic T lymphocytes specific for immune alloantigens controlled by alleles of the Ly system have been induced in vivo. These results were obtained either in a secondary type of response or by treating mice before immunization with a single dose of cyclophosphamide (80 mg/kg).
D000483:Alleles; D000818:Animals; D002478:Cells, Cultured; D003520:Cyclophosphamide / Q000008:administration & dosage; D003601:Cytotoxicity Tests, Immunologic; D007114:Immunization; D007519:Isoantigens; D051379:Mice; D008815:Mice, Inbred Strains; D013601:T-Lymphocytes / Q000276:immunology*
D007519:Isoantigens; D003520:Cyclophosphamide