title: The solvent action of sodium hypochlorite on fixed and unfixed necrotic tissue.
abstract: This study was carried out to answer the questions concerning the percentage of sodium hypochlorite needed to dissolve necrotic tissue and parachlorophenol- or formaldehyde-fixed necrotic tissue and the effect of the combined use of sodium hypochlorite and hydrogen peroxide. The results of this investigation indicate that a 3 percent concentration of sodium hypochlorite is optimum for the production of an adequate solvent action on necrotic tissue. A combination of sodium hypochlorite with 3 percent hydrogen peroxide did not result in an increased solvent action; therefore, their simultaneous use is not recommended.
mesh_terms: D000818:Animals; D002733:Chlorophenols / Q000494:pharmacology*; D003238:Connective Tissue / Q000503:physiopathology; D003790:Dental Pulp Necrosis / Q000503:physiopathology*; D005404:Fixatives / Q000494:pharmacology*; D005557:Formaldehyde / Q000494:pharmacology*; D006861:Hydrogen Peroxide / Q000494:pharmacology; D009336:Necrosis / Q000503:physiopathology*; D051381:Rats; D012390:Root Canal Therapy; D012973:Sodium Hypochlorite / Q000494:pharmacology*; D012997:Solvents; D013997:Time Factors
chemical_list: D002733:Chlorophenols; D005404:Fixatives; D012997:Solvents; D005557:Formaldehyde; D006861:Hydrogen Peroxide; D012973:Sodium Hypochlorite