Chemical aspects of radiosensitization. Reaction of sensitizers with radicals produced in the radiolysis of aqueous solutions of nucleic acid components.
The effects of oxidants (sensitizers) in the radiolysis of aqueous solutions of pyrimidine and purine bases have been investigated. Their influence on the nature of the permanent radiolysis products and on the kinetics of disappearance of transient intermediates is reported. Particular attention has been paid to the chemical fates of carbocationic intermediates which can be produced from radical-sensitizer interaction.
D000225:Adenine; D006151:Guanosine; D011687:Purines / Q000528:radiation effects*; D011743:Pyrimidines / Q000528:radiation effects*; D011838:Radiation-Sensitizing Agents / Q000494:pharmacology*; D011854:Radiochemistry
D011687:Purines; D011743:Pyrimidines; D011838:Radiation-Sensitizing Agents; D006151:Guanosine; D000225:Adenine