title: A simple ultrasound method to characterize in vitro plaque inhibition activity.
abstract: A method employing ultrasound vibration for evaluating in vitro plaque derived from Streptococcus mutans was developed. It successfully detected small changes in the cohesive/adhesive characteristics of deposits briefly exposed to several antibacterials and "antiadherents". Increased structural fragility and diminished plaque growth were generally associated with the antibacterials.
mesh_terms: D000268:Adhesiveness; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001548:Benzalkonium Compounds / Q000494:pharmacology; D002241:Carbohydrates / Q000032:analysis; D002594:Cetylpyridinium / Q000494:pharmacology; D002710:Chlorhexidine / Q000494:pharmacology; D003773:Dental Plaque / Q000032:analysis / Q000382:microbiology / Q000503:physiopathology / Q000517:prevention & control*; D006801:Humans; D011136:Polysorbates / Q000494:pharmacology; D013295:Streptococcus mutans / Q000378:metabolism; D014465:Ultrasonics
chemical_list: D000900:Anti-Bacterial Agents; D001548:Benzalkonium Compounds; D002241:Carbohydrates; D011136:Polysorbates; D002594:Cetylpyridinium; D002710:Chlorhexidine