Ultrastructural autoradiographic study of blast cells in the mouse thymus. Interest for radioleukemia research.
Ultrastructural autoradiographic studies of mouse thymic blast cells after H3 Tdr injection show that their fine nuclear structure is related to their position in the cell cycle. The variations in the composition of the subcapsular blast cell population during radiation-induced leukemogenesis indicate kinetic changes in thymic lymphopoiesis, which are probably due to the oncogenic process.
D000818:Animals; D001345:Autoradiography; D002453:Cell Cycle; D005260:Female; D007953:Leukemia, Radiation-Induced / Q000473:pathology*; D008213:Lymphocyte Activation; D051379:Mice; D013601:T-Lymphocytes / Q000648:ultrastructure*; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D014316:Tritium; D013936:Thymidine