title: Anti-DNA antibodies in discoid lupus erythematosus. Follow-up study.
abstract: Anti-DNA antibodies have been detected previously in patients with chronic discoid lupus erythematosus (DLE) despite the absence of overt systemic manifestations. 27 patients with DLE were followed up 3 years after the detection of anti-DNA antibodies in 7. None had developed other features of systemic lupus erythematosus. We conclude that the occasional finding of anti-DNA antibodies in patients with DLE does not predict those likely to develop systemic disease.
mesh_terms: D000368:Aged; D000974:Antibodies, Antinuclear; D004247:DNA / Q000276:immunology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000276:immunology*; D008875:Middle Aged
chemical_list: D000974:Antibodies, Antinuclear; D004247:DNA