Penetration of misonidazole after intravesical administration in cases of carcinoma of the bilharzial bladder.
The penetration of misonidazole was studied by a semiquantitative T.L.C. method after intravesical administration 2 h before total cystectomy in cases of carcinoma of the Bilharzial bladder. In 5 out of 7 cases misonidazole was found at a concentration of the order of 0.4 mg/g in the superficial and deep parts of the tumour, but not in normal bladder tissues.
D006801:Humans; D009593:Nitroimidazoles / Q000008:administration & dosage / Q000378:metabolism*; D012552:Schistosomiasis / Q000378:metabolism*; D001749:Urinary Bladder Neoplasms / Q000378:metabolism*
D009593:Nitroimidazoles