Paternal age effect in fibrodysplasia ossificans progressiva.
Analysis by the method of Smith (1972) of birth order and parental age data collected from 38 of 42 patients with fibrodysplasia ossificans progressive shows a significant paternal age effect. This finding among the sporadically occurring cases would support the proposition that this condition usually arises as a new dominant mutation.
D000328:Adult; D001722:Birth Order; D005260:Female; D005356:Fibromyalgia / Q000235:genetics*; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D008423:Maternal Age; D008875:Middle Aged; D009154:Mutation; D009221:Myositis Ossificans / Q000235:genetics*; D010331:Paternal Age; D013577:Syndrome