Susceptibility of human lymphocyte populations to infection by herpes simplex virus.
The antibody response to diphtheria toxoid by cultured tonsil cells was suppressed by herpes simplex virus during its inductive stage. Since only T lymphocytes readily supported virus replication, this immunosuppression may be attributed to a selective effect of the virus on this population of cells.
D000917:Antibody Formation; D002478:Cells, Cultured; D004168:Diphtheria Toxoid; D006561:Herpes Simplex / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000096:biosynthesis; D007165:Immunosuppression Therapy; D013601:T-Lymphocytes / Q000276:immunology*; D014779:Virus Replication
D004168:Diphtheria Toxoid; D007136:Immunoglobulins