Bacillus laterosporus endophthalmitis.
A strain of Bacillus laterosporus was isolated from the aqueous and vitreous humors of a patient with endophthalmitis that developed after a penetrating injury of the cornea. Intravitreal inoculation of the isolate into rabbits produced severe panophthalmitis, corneal perforation, orbital cellulitis, and even meningitis. These observations suggest that B laterosporus, hitherto classified as nonpathogenic, is an opportunist that can cause disease when conditions are favorable.
D000328:Adult; D000818:Animals; D001082:Aqueous Humor / Q000382:microbiology; D001407:Bacillus / Q000302:isolation & purification; D001424:Bacterial Infections; D065306:Corneal Injuries; D009877:Endophthalmitis / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D008297:Male; D011817:Rabbits; D014950:Wounds, Penetrating / Q000150:complications