Effect of corticosteroids on exercise-induced lymphocytosis.
Eight subjects ran on a treadmill at 8 miles per hr for 10 min. All developed lymphocytosis with predominant effect on the B cells. This was repeated 5 hr after receiving 60 mg of Prednisone. The lymphocytosis of both T and B cells were suppressed. When this was repeated 2 hr after receiving Prednisone, only lymphocytosis of the T subpopulation was suppressed. It was concluded that corticosteroid administration could suppress entry of lymphocytes into the circulation, with preponderant effect on the T subpopulation.
D000328:Adult; D001402:B-Lymphocytes / Q000187:drug effects*; D006801:Humans; D007958:Leukocyte Count; D008218:Lymphocytosis; D008297:Male; D005082:Physical Exertion; D011241:Prednisone / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000187:drug effects*
D011241:Prednisone