title: Chronic myeloid leukemia with permanent disappearance of the Ph1 chromosome and development of new clonal subpopulations.
mesh_terms: D000328:Adult; D001854:Bone Marrow Cells; D002904:Chromosomes, Human, 21-22 and Y; D002999:Clone Cells; D003114:Colony-Forming Units Assay; D006801:Humans; D007621:Karyotyping; D007951:Leukemia, Myeloid / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D008213:Lymphocyte Activation; D008297:Male