[Effect of furosemide and ethacrynic acid on sodium transport and potassium secretion].
Ethacrinic acid (0.5 mg/ml), similarly to strophanthin K, increased sodium content and decreased potassium content in the tissue of the frog urinary bladder. Furocemide (0.1 mg/ml) failed to change the ionic content of this tissue. These data indicated a difference in the intracellular action of furosemide and ethacrynic acid.
D000818:Animals; D001001:Anura; D001693:Biological Transport, Active / Q000187:drug effects; D004976:Ethacrynic Acid / Q000494:pharmacology*; D005665:Furosemide / Q000494:pharmacology*; D011188:Potassium / Q000378:metabolism*; D011896:Rana temporaria; D012964:Sodium / Q000378:metabolism*; D001743:Urinary Bladder / Q000187:drug effects* / Q000378:metabolism
D005665:Furosemide; D012964:Sodium; D004976:Ethacrynic Acid; D011188:Potassium
Vliianie furosemida i étakrinovoĭ kisloty na transport natriia i sekretsiiu kaliia.