Surface marker and other characteristics of Gaucher's cells.
A full surface marker study of the splenic storage cells in a case of Gaucher's disease largely substantiates the monocyte/histiocyte nature of Gaucher's cells. In addition, an apparent T-lymphocyte deficiency is demonstrated in the spleen and peripheral blood, and the possible significance of this finding is discussed.
D002457:Cell Extracts / Q000276:immunology; D002648:Child; D005260:Female; D005776:Gaucher Disease / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007958:Leukocyte Count; D011947:Receptors, Antigen, B-Cell / Q000032:analysis; D012397:Rosette Formation; D013154:Spleen / Q000276:immunology* / Q000648:ultrastructure; D013601:T-Lymphocytes / Q000276:immunology
D002457:Cell Extracts; D011947:Receptors, Antigen, B-Cell