Novel arabinofuranosyl derivatives of cytosine resistant to enzymatic deamination and possessing potent antitumor activity.
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000378:metabolism / Q000627:therapeutic use; D002460:Cell Line; D003561:Cytarabine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism / Q000627:therapeutic use; D003564:Cytidine Deaminase / Q000378:metabolism; D003641:Deamination; D006801:Humans; D007939:Leukemia L1210 / Q000188:drug therapy; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D051379:Mice
D000970:Antineoplastic Agents; D003561:Cytarabine; D003564:Cytidine Deaminase