title: Dentin permeability: changes produced by iontophoresis.
abstract: Iontophoretic currents (0--1.0 mA) were applied to dentin disks prepared from human third molars. A negative electrode increased 125I-permeation 10X, while a positive electrode increased 14C-lidocaine 8X. Iontophoresis appears promising as a method to increase the permeation of dentin by ionized substances of therapeutic interest.
mesh_terms: D002250:Carbon Radioisotopes / Q000378:metabolism; D003804:Dentin / Q000378:metabolism; D003806:Dentin Permeability; D004058:Diffusion; D006801:Humans; D007457:Iodine Radioisotopes / Q000378:metabolism; D007478:Iontophoresis / Q000379:methods; D008012:Lidocaine / Q000378:metabolism; D014088:Tooth Permeability
chemical_list: D002250:Carbon Radioisotopes; D007457:Iodine Radioisotopes; D008012:Lidocaine