title: Tissue formation in the root canal after total pulpectomy and partial root filling.
abstract: In twenty human teeth, total removal of the pulp was attempted, and the root canal was filled 2 to 4 mm. short of the foramen in the same sitting. The root filling consisted of gutta-percha points and Kloroperka N-ö as a sealer. The teeth were extracted after observation periods of 2, 6, and 10 months and committed to histologic examination. Microscopic evaluation demonstrated that after 2 months, the space in the canal between the root filling and the foramen was occupied by connective tissue slightly inflamed in the area adjacent to the root filling. After 6 and 10 months the entire space contained a fully developed cell-rich fibrous tissue, and only a few lymphocytes were observed adjacent to the root filling material.
mesh_terms: D000328:Adult; D000368:Aged; D002725:Chloroform; D003238:Connective Tissue / Q000033:anatomy & histology; D003786:Dental Pulp Cavity / Q000033:anatomy & histology / Q000502:physiology*; D006171:Gutta-Percha; D006801:Humans; D008875:Middle Aged; D011670:Pulpectomy; D012387:Root Canal Filling Materials; D012389:Root Canal Obturation / Q000379:methods*; D014092:Tooth Root / Q000033:anatomy & histology
chemical_list: D012387:Root Canal Filling Materials; D002725:Chloroform; D006171:Gutta-Percha