title: The management of drug induced gingival hyperplasia in mentally retarded patients with hemophilia: a report of two cases.
abstract: Two cases of hemophilia in severely mentally retarded patients with drug-induced gingival hyperplasia are presented. The method of management in each case is described. A conservative approach is recommended in which tissue removals and only selected extractions are performed. It is also suggested that the sequela of dilantin hyperplasia be considered when dilantin is used in patients with hemophilia or severely mentally retarded patients whose oral hygiene may be difficult to maintain. If feasible, as in the first case reported, discontinuance of the drug should be considered. In case 2 the patient is presently being weaned from dilantin therapy. It should be understood that the authors are concerned with the immediate clinical management of drug-induced gingival hyperplasia in mentally-retarded patients with hemophilia. Although this method of management has proved successful in the hands of the authors, we do not have data to show that it is the best form of treatment for these patients.
mesh_terms: D000328:Adult; D002648:Child; D005884:Gingival Hemorrhage / Q000209:etiology*; D005885:Gingival Hyperplasia / Q000139:chemically induced*; D006467:Hemophilia A; D006801:Humans; D008607:Intellectual Disability; D008297:Male; D006472:Oral Hemorrhage / Q000209:etiology*; D010672:Phenytoin / Q000009:adverse effects*
chemical_list: D010672:Phenytoin