title: Antimicrobial effectiveness in endodontic therapy using formocresol and two new alcoformol agents. Mechanical preparation during the first visit.
abstract: Antimicrobial effectiveness of two alcoformol agents (AF 8.75 and AF 3.5) was studied in a clinical trial by means of bacteriologic examination of the root canals. After the initial culture was taken, the root canal was reamed and a second culture was taken. One of the disinfectants was sealed in the pulp chamber for one week. At the second visit, a third culture was taken. No statistically significant differences were found between the effectiveness of the disinfectants; the cumulative effect of mechanical preparation and disinfection was such that initially positive teeth did not differ significantly from initially negative teeth when treated by this procedure.
mesh_terms: D000891:Anti-Infective Agents, Local; D001419:Bacteria / Q000187:drug effects; D003786:Dental Pulp Cavity / Q000382:microbiology; D004202:Disinfectants / Q000494:pharmacology; D004341:Drug Evaluation; D000431:Ethanol / Q000494:pharmacology; D005557:Formaldehyde / Q000494:pharmacology*; D005566:Formocresols / Q000494:pharmacology*; D006801:Humans; D011670:Pulpectomy; D012390:Root Canal Therapy; D013997:Time Factors
chemical_list: D000891:Anti-Infective Agents, Local; D004202:Disinfectants; D005566:Formocresols; D005557:Formaldehyde; C019241:alcoformol; D000431:Ethanol