title: High-dose methotrexate therapy with citrovorum factor: a pharmacologic perspective in murine tumor models.
mesh_terms: D000818:Animals; D004247:DNA / Q000096:biosynthesis; D004273:DNA, Neoplasm / Q000096:biosynthesis; D004359:Drug Therapy, Combination; D007421:Intestine, Small / Q000187:drug effects / Q000378:metabolism; D007700:Kinetics; D002955:Leucovorin / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D007939:Leukemia L1210 / Q000188:drug therapy / Q000378:metabolism; D008727:Methotrexate / Q000008:administration & dosage* / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D051379:Mice; D009374:Neoplasms, Experimental / Q000188:drug therapy* / Q000378:metabolism; D012510:Sarcoma 180 / Q000188:drug therapy / Q000378:metabolism; D013997:Time Factors
chemical_list: D004273:DNA, Neoplasm; D004247:DNA; D002955:Leucovorin; D008727:Methotrexate