title: [Immunological aspects of pulmonary granulomatosis with special reference to sarcoidosis].
abstract: A wide variety of exogenous or endogenous aggressors exhibit the capacity to induce pulmonary granulomatous lesions. This lesion is characterized by exacerbation of phagocytic function and tentative development of a specific immune response. In many clinical situations there is a well developed circulating antibody response with deficient cell-mediated immunity of variable degree. Finally, it is argued that the granulomatous lesion may be due to abnormal cooperation between T and B lymphocytes.
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D000936:Antigen-Antibody Complex; D001323:Autoantibodies / Q000032:analysis; D001402:B-Lymphocytes / Q000276:immunology; D006099:Granuloma / Q000276:immunology*; D006801:Humans; D007731:Kveim Test; D008171:Lung Diseases / Q000276:immunology*; D008213:Lymphocyte Activation; D012217:Rheumatoid Factor / Q000032:analysis; D012507:Sarcoidosis / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D000936:Antigen-Antibody Complex; D001323:Autoantibodies; D012217:Rheumatoid Factor
vernacular_title: Aspects immunologiques des granulomatoses pulmonaires avec référence spéciale à la sarcoïdose