title: Differential effects of basolateral amygdala lesions on behavior, corticosterone, and prolactin responses.
abstract: The present experiment examines hormone-behavior relationships following manipulation of the amygdala. Affective behavior and levels of corticosterone and prolactin were compared in rats with lesions of the basolateral amygdala and in nonlesioned and sham-operated controls. Animals with lesions of the basolateral amygdala were found to be hyperreactive and to have normal resting levels of corticosterone and prolactin but potentiated corticosterone responses to stress. Normal prolactin stress responses were unaltered by the lesion. The results are discussed in relation to behavioral and endocrine changes seen following other limbic system lesions.
mesh_terms: D000679:Amygdala / Q000502:physiology*; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D002940:Circadian Rhythm; D003345:Corticosterone / Q000097:blood*; D004644:Emotions / Q000502:physiology; D008297:Male; D011388:Prolactin / Q000097:blood*; D051381:Rats; D013216:Reflex, Startle / Q000502:physiology; D013312:Stress, Physiological / Q000097:blood
chemical_list: D011388:Prolactin; D003345:Corticosterone