Studies on hemolytic activity of bisphenol A diglycidyl methacrylate (BIS-GMA).
To clarify the high hemolytic activity of BIS-GMA, the molar concentration producing 50% hemolysis (H50) and the partition coefficient inoctanol-water were determined using BIS-GMA and various types of methacrylates. It is suggested that the strong hemolytic potency of BIS-GMA is due to the high hydrophobic nature of the compound.
D000179:Acrylates / Q000494:pharmacology*; D000180:Acrylic Resins / Q000494:pharmacology; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D004285:Dogs; D006461:Hemolysis / Q000187:drug effects*; D008689:Methacrylates / Q000494:pharmacology*; D008768:Methylmethacrylates / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000179:Acrylates; D000180:Acrylic Resins; D008689:Methacrylates; D008768:Methylmethacrylates