[Cold-lymphocytotoxic antibodies in the sera of cervix-carcinoma patients].
Sera of 120 patients with cervical cancer were screened for cold reacting, complement dependant autolympho-cytotoxins (CoCoCy). These antibodies occurred in 21,7% of the patients in comparison with 11,2% of 116 controls. The highest percentage of CoCoCy-antibodies was detected in the sera of patients with cervical cancer stage I (27,6%). Thus demonstration of CoCoCy-antibodies may be of pathogenetic rather than of diagnostic interest. CoCoCy-antibodies could be seen to reflect autoimmune reactions in cervical cancer.
D001323:Autoantibodies / Q000032:analysis; D003080:Cold Temperature; D005260:Female; D006801:Humans; D008233:Lymphotoxin-alpha / Q000032:analysis*; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology; D002583:Uterine Cervical Neoplasms / Q000276:immunology* / Q000473:pathology
D001323:Autoantibodies; D008233:Lymphotoxin-alpha
Kälte-lymphozytotoxische Antikörper (CoCoCy) in Seren von Cervix-Karzinom-Patientinnen (CCa).