Circulating mitotic cells in the newborn infant. The preparation of karyotypes without prior cell culture.
A method is described which permits the rapid chromosome analysis, without prior culturing, of newborn infants suspected of having chromosomal abnormalities. This was accomplished by the direct preparation of karyotypable slides from in vivo circulating mitotic cells taken from  placental cord blood immediately after delivery.
D001777:Blood Coagulation; D001793:Blood Preservation; D002875:Chromosomes; D005260:Female; D005312:Fetal Blood / Q000166:cytology*; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping / Q000379:methods*; D008297:Male; D008938:Mitosis; D012737:Sex Factors