title: The effects of overfilled polyethylene tube intraosseous implants in rats.
abstract: Polyethylene tubes obturated flush at one end overfilled 2 mm. at the opposite end with unset Grossman's cement and gutta-percha were implanted in rat tibias. Microscopic evaluation of the specimens revealed that (1) the gutta-percha, Grossman's sealer, and polyethylene tubing are well tolerated by rat intraosseous tissue and (2) a canal overextended 2 mm. beyond the apex with Grossman's cement and gutta-percha produces an early mild to moderate inflammatory response which resolves by the end of 30 day's. The overfillings did not significantly compromise the healing of rat intraosseous tissue.
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001842:Bone and Bones / Q000033:anatomy & histology / Q000187:drug effects* / Q000601:surgery; D003738:Dental Cements / Q000494:pharmacology*; D006171:Gutta-Percha / Q000494:pharmacology*; D007440:Intubation / Q000295:instrumentation; D008297:Male; D010000:Osteitis / Q000473:pathology; D011095:Polyethylenes; D051381:Rats; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials; D003738:Dental Cements; D011095:Polyethylenes; D012387:Root Canal Filling Materials; D006171:Gutta-Percha