[The protective effect of sodium selenite and vitamin E in hypervitaminosis D].
Vitamin D2 (160 000-240 000 IU/kg) produced during 5 days pronounced hypercalciemia and metastatic calcification of internal organs. Subcutaneous injection of sodium selenite (10 mg/kg) brought down the level of calcium in the blood plasma and decreased calcification of internal organs. Conjoint introduction of sodium selenite (30 gamma/kg) and of vitamin "E" (50 mg/kg) lowered the aortal calcinosis by 54 per cent, of the lung--by 93, of the heart--by 86 and of the kidney--by 96 per cent.
D000818:Animals; D004359:Drug Therapy, Combination; D004872:Ergocalciferols / Q000506:poisoning*; D008297:Male; D051381:Rats; D012643:Selenium / Q000008:administration & dosage / Q000627:therapeutic use*; D014810:Vitamin E / Q000008:administration & dosage / Q000627:therapeutic use*
D004872:Ergocalciferols; D014810:Vitamin E; D012643:Selenium
Zashchitnoe deĭstvie selenita natriia i vitamina E pri D-gipervitaminoze