[Specificity of the effect of thrombin on the chemoreceptors of the frog carotid labyrinth].
Perfusion of thrombin and trypsin solutions through the frog carotid labyrinth acts on the carotid chemoreceptors and evokes reflex response of the anticoagulating system. The similarity of effects of both these agents seems to be due to similarity of their structures. Other agents acting on the frog vascular chemoreceptors: sodium chloride hypoxia, lobeline,--cause no activation of the reflex anticoagulating system. Thrombin is concluded to be the adequate and specific irritant of the vascular chemoreceptors of the frog anticoagulating system.
D000818:Animals; D001001:Anura; D001777:Blood Coagulation; D002339:Carotid Arteries / Q000294:innervation*; D002628:Chemoreceptor Cells / Q000187:drug effects*; D008120:Lobeline / Q000494:pharmacology; D008297:Male; D010100:Oxygen / Q000097:blood; D010525:Peripheral Nerves / Q000502:physiology; D011896:Rana temporaria; D012018:Reflex; D012965:Sodium Chloride / Q000494:pharmacology; D013917:Thrombin / Q000494:pharmacology*; D014357:Trypsin / Q000494:pharmacology
D012965:Sodium Chloride; D008120:Lobeline; D014357:Trypsin; D013917:Thrombin; D010100:Oxygen
O spetsifichnosti deĭstviia trombina na khemoretseptory karotidnogo labirinita liagushki