Cell-mediated immunity in pregnancy evaluated using lymphocyte transformation tests and rosette tests for T and B lymphocytes. A cross-section analysis.
In vitro tests of cellular immune response using lymphocyte transformation tests and rosette tests for T and B lymphocytes were studied in a cross-section analysis of a total of 55 patients in six groups (non-pregnant, 2-3 month pregnant, 4-5 month pregnant, 6-7 month pregnant, at parturition and 3 months after parturition). No pregnancy-related changes were found in the numbers of T, B or nil cells, nor changes in PHA, PWM or MLC responses. However, a significant reversible depression of the PPD response was found in the second half of pregnancy.
D000328:Adult; D001402:B-Lymphocytes; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008213:Lymphocyte Activation; D011247:Pregnancy; D012397:Rosette Formation; D013601:T-Lymphocytes