title: Improvement of the efficiency of ion-exchange cellulose columns and their application.
abstract: Packing procedures and operating conditions for microparticulate ion-exchange cellulose columns were investigated. The efficiencies of ion-exchange cellulose and mixed-bed ion-exchange cellulose columns were compared. The mixed-bed columns contained ion-exchange cellulose and diatomite, and those with a 5:1 volume ratio of ion-exchange cellulose (average particle size 7 micronm) and diatomite were found to be superior in almost every respect. Medical, pharmaceutical, biochemical and environmental applications of this type of column are shown.
mesh_terms: D002482:Cellulose; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002852:Chromatography, Ion Exchange / Q000379:methods*; D007612:Kanamycin / Q000032:analysis; D002955:Leucovorin / Q000097:blood; D008727:Methotrexate / Q000097:blood; D009675:Novobiocin / Q000032:analysis
chemical_list: D009675:Novobiocin; D007612:Kanamycin; D002482:Cellulose; D002955:Leucovorin; D008727:Methotrexate