title: [Clinical studies of the therapeutic effect of the combination of spiramycin and metronidazole in dental and stomatological diseases].
abstract: The therapeutic effect and clinical tolerance of an association of spiramycin and metronidazole were assessed in 20 patients with odontostomatological inflammation. The results were regarded as satisfactory with regard to the length of treatment and the progression of the clinical picture in 90% of the cases treated. Unwanted side-effects, not sufficiently severe to stop the treatment, were noted in only 2 cases. Comparison with the results obtained in a control series treated with spiramycin only showed that the combination was more effective, though the difference was not significant, and letter tolerated.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D005891:Gingivitis / Q000188:drug therapy; D006801:Humans; D007933:Leucomycins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D009059:Mouth Diseases / Q000188:drug therapy*; D010497:Pericoronitis / Q000188:drug therapy; D010518:Periodontitis / Q000188:drug therapy; D013280:Stomatitis / Q000188:drug therapy
chemical_list: D004338:Drug Combinations; D007933:Leucomycins; D008795:Metronidazole
vernacular_title: Indagine clinica sull'effetto terapeutico dell'associazione spiramicina-metronidazolo in campo odontostomatologico.