Human labia majora skin: transepidermal water loss in vivo.
Transepidermal water (TEW) loss of normal vulvar and flexor forearm skin was measured in 12 subjects. A significantly elevated vulvar TEW loss was demonstrated. Depsite subcutaneous administration of atropine in seven subjects to eliminate eccrine sweating, no alteration in the elevated TEW loss was found. A significant anatomic and/or physiologic uniqueness of vulvar skin is demonstrated and warrants further investigation.
D000328:Adult; D001285:Atropine / Q000008:administration & dosage / Q000494:pharmacology; D004817:Epidermis / Q000502:physiology; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D008875:Middle Aged; D012879:Skin Physiological Phenomena; D013546:Sweating / Q000187:drug effects; D014844:Vulva / Q000502:physiology*; D014870:Water Loss, Insensible / Q000187:drug effects
D001285:Atropine