title: Spectroscopic studies of oxy- and carbonmonoxyhemoglobin after pulsed optical excitation.
abstract: The photolysis of HbO2 and HbCO has been investigated with picosecond laser techniques. Transient absorption spectra were measured in the Soret and visible regions after excitation with 353- or 530-nm pulses. The photoproducts appeared within 8 psec and exhibited considerably broadened deoxyhemoglobin-like spectra, which persisted to 680 psec. The altered spectra are attributed to the production of deoxyheme conformational and spin states that might result from the intense excitation.
mesh_terms: D002263:Carboxyhemoglobin; D006454:Hemoglobins; D006801:Humans; D007700:Kinetics; D007834:Lasers; D010108:Oxyhemoglobins; D010782:Photolysis; D013053:Spectrophotometry
chemical_list: D006454:Hemoglobins; D010108:Oxyhemoglobins; D002263:Carboxyhemoglobin