Cytogenetic and clinical findings in mares with gonadal dysgenesis.
Gonadal dysgenesis in the mare is associated with several different karyotypes, including sex chromosome aneuploidy (63,X; 63,X/64,XX; 63,X/64,XY or 65,XXX), the normal male complement (64,XY) and autosomal deletion (64,XX?del2q-). The 63,X is the most common karyotype found in gonadal dysgenesis. Aneuploid cases probably represent spontaneous chromosome non-disjunction during oogenesis, spermatogenesis or early embryonic development. Cases with XY or autosomal deletion may be inherited defects or of spontaneous origin.
D000782:Aneuploidy; D000818:Animals; D001789:Blood Group Antigens; D002872:Chromosome Deletion; D005260:Female; D005838:Genotype; D006059:Gonadal Dysgenesis / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D006734:Horse Diseases / Q000235:genetics* / Q000473:pathology; D006736:Horses / Q000235:genetics; D007621:Karyotyping; D010641:Phenotype
D001789:Blood Group Antigens