title: A maximum likelihood map of chromosome 1.
abstract: Thirteen loci are mapped on chromosome 1 from genetic evidence. The maximum likelihood map presented permits confirmation that Scianna (SC) and a fourteenth locus, phenylketonuria (PKU), are on chromosome 1, although the location of the latter on the PGM1-AMY segment is uncertain. Eight other controversial genetic assignments are rejected, providing a practical demonstration of the resolution which maximum likelihood theory brings to mapping.
mesh_terms: D002874:Chromosome Mapping; D002900:Chromosomes, Human, 1-3; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D008297:Male; D010661:Phenylketonurias / Q000235:genetics; D011110:Polymorphism, Genetic
chemical_list: D005819:Genetic Markers