[Preliminary analysis of intensive treatment of acute lymphoblastic leukemia in children].
The analysis was carried out on 31 children with acute lymphoblastic leukaemias. In 29 of them remissions were obtained conducting later during 3 years intensive maintenance therapy associated with radiotherapy to the central nervous system (according to the method of the Memphis group). Superiority of intensive treatment in relation to more sparing treatment has been demonstrated. Therapeutic failures were observed in children with primarily poor prognosis of leukaemia, especially with blastic hyperleucocytosis. The behavior of serum immunoglobulins and especially infections occurring in children during treatment are discussed.
D000367:Age Factors; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination / Q000379:methods; D006801:Humans; D007223:Infant; D007945:Leukemia, Lymphoid / Q000188:drug therapy*; D012008:Recurrence; D012075:Remission, Spontaneous
D000970:Antineoplastic Agents
Wstepna analiza wyników intensywnego leczenia ostrych bialaczek limfoblastycznych u dzieci.