title: Transmembrane potentials of osteoblasts.
abstract: Transmembrane potentials were recorded in situ from osteoblasts on the parietal bones of albino rat pups, 3 to 24 days of age. Osteoblasts exhibit a uniquely low polarization of their cell membranes (3.93 mV, inside negative). Osteoblasts respond rapidly, but transiently, to parathyroid hormone by depolarization, and to thyrocalcitonin by hyperpolarization.
mesh_terms: D000818:Animals; D002116:Calcitonin / Q000494:pharmacology; D002462:Cell Membrane / Q000187:drug effects / Q000502:physiology*; D008564:Membrane Potentials / Q000187:drug effects*; D010006:Osteoblasts / Q000187:drug effects / Q000502:physiology*; D010281:Parathyroid Hormone / Q000494:pharmacology; D010294:Parietal Bone / Q000166:cytology; D051381:Rats
chemical_list: D010281:Parathyroid Hormone; D002116:Calcitonin