15/17 translocation in acute promyelocytic leukaemia.
A translocation between a chromosome 15 and a chromosome 17 was found in the bone marrow of a 14-year-old boy who had clinical and laboratory symptoms of acute promyelocytic leukemia (APL). As far as we know, this is the sixth case of APL with 15/17 translocation to be reported in the literature. This observation gives further support to the hypothesis that there is an association between this chromosomal rearrangement and APL.
D000293:Adolescent; D001853:Bone Marrow / Q000648:ultrastructure; D002901:Chromosomes, Human, 13-15; D002902:Chromosomes, Human, 16-18; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic