title: Cardio-circulatory effects of enflurane anesthesia in health and disease.
abstract: The circulatory effects of enflurane (Ethrane) were studied in 10 unmedicated volunteers during anesthesia over a period of 90 min or more. Cardiac output did not change significantly at a mean alveolar concentration of 2.3 vol.%. Heart rate was increased in all cases. Enflurane causes negative inotropic activity in the heart muscle but has little influence on the pump performance of the heart.
mesh_terms: D000769:Anesthesia, Inhalation; D001775:Blood Circulation / Q000187:drug effects*; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects*; D004737:Enflurane / Q000009:adverse effects / Q000494:pharmacology*; D006801:Humans; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D004737:Enflurane