The hyperthermic potentiation of the cytotoxic effect of misonidazole on the EMT6 mouse tumour: relevance of in vitro measurement of in vivo effect.
The effect of local hyperthermia combined with misonidazole and the influence of temperature monitoring on this effect in growth delay studies and in vitro colony assay are described.
D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D006358:Hot Temperature; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009374:Neoplasms, Experimental / Q000628:therapy*; D009593:Nitroimidazoles / Q000494:pharmacology*; D013997:Time Factors
D009593:Nitroimidazoles