[New aspects in the pathogenesis of anemia in chronic polyarthritis].
In 44 patients with rheumatoid arthritis and 30 control persons, the activities of the following three hemesynthesizing enzymes were determined: delta-aminolevulinic acid dehydratase (D-ALA-D), porphobilinogen deaminase (PBG-D), and ferrochelatase (FCH). Compared with the control persons in patients with rheumatoid arthritis, statistically significant decreased activities of FCH were determined, whereas no differences between the two groups tested occurred with D-ALA-D and PBG-D.
D000740:Anemia / Q000201:enzymology*; D001172:Arthritis, Rheumatoid / Q000201:enzymology*; D005294:Ferrochelatase / Q000097:blood; D006418:Heme / Q000096:biosynthesis*; D006801:Humans; D011163:Hydroxymethylbilane Synthase / Q000097:blood; D000623:Porphobilinogen Synthase / Q000097:blood
D006418:Heme; D011163:Hydroxymethylbilane Synthase; D000623:Porphobilinogen Synthase; D005294:Ferrochelatase
Neue Aspekte in der Genese der Anämie bei chronischer Polyarthritis.