Von Willebrand's disease and pregnancy.
The course of a pregnant patient with von Willebrand's disease, who underwent a successful cesarean section without supportive Factor VIII therapy is described. She had no postoperative bleeding despite a persistently prolonged bleeding time. The significance of the bleeding time, Factor VIII activity, and Factor VIII-related antigen in relation to bleeding tendency and therapeutic management is discussed.
D000328:Adult; D000941:Antigens; D001780:Blood Coagulation Tests; D002585:Cesarean Section; D005169:Factor VIII / Q000378:metabolism; D005260:Female; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000628:therapy*; D014842:von Willebrand Diseases / Q000097:blood / Q000628:therapy*
D000941:Antigens; D005169:Factor VIII