Morphological evidence for the presence of the endogenous guinea-pig retravirus in the lymphoblasts of L2C leukemia.
Peripheral blood samples of a transplantable guinea-pig leukemia revealed that, only during the terminal stages of the disease, leukemic cells produce virus particles indistinguishable from the RNA tumor viruses of the Retraviridae family genus Oncorna virus B.
D000818:Animals; D006168:Guinea Pigs; D007181:Inclusion Bodies, Viral; D007942:Leukemia, Experimental / Q000382:microbiology / Q000648:ultrastructure; D007945:Leukemia, Lymphoid / Q000382:microbiology* / Q000648:ultrastructure; D008214:Lymphocytes / Q000382:microbiology; D012190:Retroviridae / Q000254:growth & development* / Q000648:ultrastructure