Disseminated BCG disease associated with immunotherapy by scarification in acute leukemia.
Disseminated BCG infection developed in a patient with acute leukemia receiving BCG immunotherapy by scarification. Predisposing factors included the underlying malignancy, intensive chemotherapy, and continuous high-dose corticosteroids. The scarification technique is safe; however, physicians should be alert to this syndrome as a cause of fever of unknown origin in cancer patients receiving BCG immunotherapy.
D000368:Aged; D001500:BCG Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007165:Immunosuppression Therapy; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000276:immunology / Q000628:therapy*; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications / Q000209:etiology; D014376:Tuberculosis / Q000150:complications / Q000209:etiology*
D001500:BCG Vaccine