title: Marsupial--mouse cell hybrids containing fragments of the marsupial X chromosome.
abstract: Hybrids were obtained from fusions of HPRT-deficient mouse fibroblasts and marsupial lymphocytes. These hybrids retained no identifiable marsupial chromosomes, but all expressed the marsupial form of HPRT. Half the clones also expressed marsupial PGK-A, and half of these also marsupial G6PD; no other marsupial allozyme markers were detected. Since G6PD is known to be sex linked in these species, we conclude that Hpt and Pgk-A are also located on the X chromosome and the markers lie in the order Hpt-Pgk-A-Gpd.
mesh_terms: D000818:Animals; D002871:Chromosome Banding; D004586:Electrophoresis; D004798:Enzymes / Q000235:genetics; D005260:Female; D005819:Genetic Markers; D006822:Hybrid Cells / Q000648:ultrastructure*; D008214:Lymphocytes / Q000648:ultrastructure; D008394:Marsupialia / Q000235:genetics*; D051379:Mice; D012730:Sex Chromosomes; D014178:Translocation, Genetic; D014960:X Chromosome
chemical_list: D004798:Enzymes; D005819:Genetic Markers