[Immunological tests in the diagnosis and prognosis of disseminated lupus erythematosus, before treatment (author's transl)].
Sixty-four patients classified according to clinical manifestations, and renal pathological lesions have been submitted to a detailed immunological study before treatment. Four tests have provided significant correlations: antinative DNA antibodies (studied by a Farr test), C3, E rosette and cryoglobulins. The simultaneous considerations of these 4 parameters is however necessary in a given patient because each of them, taken separately, has no absolute value and may sometimes be clearly abnormal in patients with apparently benign outcome.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis; D000936:Antigen-Antibody Complex; D001485:Basement Membrane / Q000276:immunology; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D003450:Cryoglobulins / Q000032:analysis; D004269:DNA, Bacterial / Q000276:immunology; D005921:Glomerulonephritis / Q000276:immunology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000276:immunology; D008231:Lymphopenia / Q000209:etiology; D008875:Middle Aged; D011379:Prognosis; D011863:Radioimmunoassay / Q000379:methods; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology
D000974:Antibodies, Antinuclear; D000936:Antigen-Antibody Complex; D003176:Complement C3; D003181:Complement C4; D003450:Cryoglobulins; D004269:DNA, Bacterial
Tests immunologiques pour le diagnostic et le pronostic du lupus érythémateux disséminé avant traitement. Intérêt et limites.