Childhood and adult acute leukaemia in Johannesburg blacks.
Thirty-four Black patients (14 children and 20 adults) suffering from acute leukaemia were assessed at the haematology clinics of Baragwanath Hospital and Johannesburg General Hospital during a recent 2-year period. It is evident that acute leukaemia in Blacks has become more prevalent in the Johannesburg area than it was 20 years ago, the increase being most striking in the younger age group. The incidence of acute myelocytic and lymphocytic leukaemia in Black children was the same. In adults acute myelocytic leukaemia predominated. The remission rate of 90% achieved in patients with acute lymphoblastic leukaemia was similar to the rates described in Europe and the USA. Results in patients with acute myelocytic leukaemia were less favourable (35% with initial complete remission). The problems of management (limited isolation facilities), complications related to prolonged hospitalization (loss of earnings, problems of visiting), and difficulties with follow-up examination are outlined. In underdeveloped and developing countries, training paramedical personnel to assist with the outpatient care of patients with neoplastic disease might alleviate some of these problems.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001741:Black or African American; D044383:Black People; D002648:Child; D002675:Child, Preschool; D005260:Female; D006412:Hematopoietic Stem Cells; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000188:drug therapy; D004915:Leukemia, Erythroblastic, Acute / Q000188:drug therapy; D007945:Leukemia, Lymphoid / Q000453:epidemiology / Q000628:therapy*; D015470:Leukemia, Myeloid, Acute / Q000453:epidemiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D013019:South Africa