title: Spiculated periosteal reaction in metastatic disease resembling osteosarcoma.
abstract: Sixteen cases of metastatic bone deposits presenting with sunburst spiculated periosteal reaction are presented. The most common origin was from prostatic carcinoma followed by neuroblastoma. A moderate soft tissue mass component was seen in 70% of the cases. The possible pathophysiologic reasons for this type of periosteal reaction are presented. The differential diagnosis is outlined.
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis; D000368:Aged; D001859:Bone Neoplasms / Q000000981:diagnostic imaging*; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005134:Eye Neoplasms / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012516:Osteosarcoma / Q000000981:diagnostic imaging*; D011471:Prostatic Neoplasms / Q000175:diagnosis; D011859:Radiography; D012175:Retinoblastoma / Q000175:diagnosis; D013274:Stomach Neoplasms / Q000175:diagnosis