Suppressor T cells in low zone tolerance. II. Characterization of suppressor T and amplifier cells by physical and serological methods.
Suppressor cells involved in low zone tolerance to bacteriophage fd have been characterized by serological and physical methods. Suppressor T cells are peripheral T2 cells which are Ly-1-, Ly-2+ and Ia+. They are of high electrophoretic mobility, sediment 5 mm/h at 1 x g in a linear Ficoll 70 gradient, but are not restricted to a distinct band in a discontinuous bovine serum albumin gradient. Adherent phagocytic cells of low electrophoretic mobility can act as amplifier cells with a much shorter half-life than suppressor T cells.
D000818:Animals; D001435:Bacteriophages / Q000276:immunology*; D002448:Cell Adhesion; D006854:Hydrocortisone / Q000494:pharmacology; D007108:Immune Tolerance; D007116:Immunization, Passive; D008297:Male; D051379:Mice; D010587:Phagocytosis; D013154:Spleen / Q000166:cytology; D013601:T-Lymphocytes / Q000276:immunology*
D006854:Hydrocortisone