[Preparation of mouse antiserum against isologous aggregated immunoglobulins and its effect on rosette forming cells].
A method of obtaining antisera against isologous aggregated mouse immunoglobulins is described. This serum designated MAAS blocked in vitro the antigen-binding receptors of the immune rosette-forming cells. MAAS was injected to mice immunized with SRBC. In comparision with the immunized mice given normal isologous serum rosette-forming B-cells were absent in the spleen of mice given MAAS at the peak of isologous response. But the antibody-forming cell count was not decreased under the influence of MAAS.
D000818:Animals; D000888:Antibodies, Anti-Idiotypic; D001402:B-Lymphocytes / Q000276:immunology*; D007106:Immune Sera; D007136:Immunoglobulins; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D012397:Rosette Formation; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D000888:Antibodies, Anti-Idiotypic; D007106:Immune Sera; D007136:Immunoglobulins
Poluchenie myshinoĭ antisyvorotki protiv izologichnykh agregirovannykh immunoglobulinov i izuchenie ee deĭstviia na rozetkoobrazuiushchie kletki.