Studies on platelet aggregation in vivo. VI. Effect of a pyrimido-pyrimidine derivative [RA233] on tumor cell metastasis.
The pyrimido-pyrimidine derivative RA 233 was found to increase circulation time and decrease metastatic settling of intravenously injected, radioisotope labeled ascites tumor cells in mice.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor; D008297:Male; D051379:Mice; D009012:Mopidamol / Q000494:pharmacology*; D009362:Neoplasm Metastasis; D009360:Neoplastic Cells, Circulating; D010974:Platelet Aggregation / Q000187:drug effects*; D011743:Pyrimidines / Q000494:pharmacology*
D011743:Pyrimidines; D009012:Mopidamol