Fluoride levels in human parotid saliva following ingestion of fluoride compounds of varying solubility.
Healthy dental students received oral doses of 10.0 mg F daily in the form of compounds of widely varying solubilities. Parotid saliva F concentration and urinary F excretion were highest with NaF, Na2PO3F, and SnF2, lowest with CaF2, and intermediate with AlF3. Solubility of the ingested fluoride compound was a controlling factor in the amount of F excreted in the urine, the peak F concentration reached in parotid saliva, and the duration of a significant elevation in salivary F.
D000042:Absorption; D000284:Administration, Oral; D000535:Aluminum / Q000008:administration & dosage; D002124:Calcium Fluoride / Q000008:administration & dosage; D005459:Fluorides / Q000008:administration & dosage* / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D010306:Parotid Gland; D010710:Phosphates / Q000008:administration & dosage; D010919:Placebos; D012463:Saliva / Q000032:analysis*; D012969:Sodium Fluoride / Q000008:administration & dosage; D012995:Solubility; D014002:Tin Fluorides / Q000008:administration & dosage
D010710:Phosphates; D010919:Placebos; D014002:Tin Fluorides; D012969:Sodium Fluoride; D000535:Aluminum; D002124:Calcium Fluoride; D005459:Fluorides