title: Alpha-1-antitrypsin globules in the liver and PiM phenotype.
abstract: The finding is recorded of typical a1-antitrypsin globules, confirmed by immunofluorescence and immunoperoxidase methods, in the hepatocytes of a patient shown to have a normal serum antitrypsin level and normal phenotype (TiM) for a1-antitrypsin. The identification of such globules can no longer be regarded as conclusive evidence of an abnormal a1-antitrypsin phenotype.
mesh_terms: D000368:Aged; D006801:Humans; D008099:Liver / Q000166:cytology*; D008297:Male; D010641:Phenotype; D000515:alpha 1-Antitrypsin / Q000302:isolation & purification*
chemical_list: D000515:alpha 1-Antitrypsin