title: Comparative studies of methotrexate and metoprine: metabolic toxicity and cell killing.
mesh_terms: D000970:Antineoplastic Agents / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D004247:DNA / Q000378:metabolism; D003857:Deoxyuridine / Q000378:metabolism; D004359:Drug Therapy, Combination; D006801:Humans; D007700:Kinetics; D007951:Leukemia, Myeloid / Q000378:metabolism; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism; D008727:Methotrexate / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D011739:Pyrimethamine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D004247:DNA; D003857:Deoxyuridine; D008727:Methotrexate; D011739:Pyrimethamine