title: Discoloration of permanent front teeth in 3,157 Norwegian children due to tetracyclines and other factors.
abstract: During routine orthodontic screening in Oslo, Norway, of 3,157 children, aged 1--11 years and born in 1963/64, 36 cases (1.14%) with cosmetically marring discoloration of permanent front teeth were registered. Thirty-four of them arrived for a more exhaustive examination, which in 24 of the children revealed positive tetracycline fluorescence on exposure to ultraviolet light. In 13 (0.4%) of the children, the discolorations were diagnosed to be tetracycline-induced. Enamel hypoplasia was frequently found in teeth with positive fluorescence. Multiple exposures to various tetracyclines were reported in all children who exhibited positive fluorescence.
mesh_terms: D002648:Child; D003744:Dental Enamel Hypoplasia / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D009664:Norway; D013754:Tetracyclines / Q000009:adverse effects*; D014075:Tooth Discoloration / Q000139:chemically induced* / Q000150:complications / Q000453:epidemiology
chemical_list: D013754:Tetracyclines