[Polymorphism of a tumor cell population and selective processes. III. A change in the correlation of tumor cell subpopulations of the ascitic strain of Ehrlich-I.Ch.Ph. under the influence of glucose and sodium succinate].
A study was made of the action of glucose or sodium succinate on subpopulations of the Ehrlich-I.Ch.Ph. ascite strain characterised by markers "A1" and "A", resp. After i.p. injection of glucose the amount of "A1"-cell reached 50 and almost 100% on the 5th and 7th day of tumor growth. After the transplantation of "A1"-cells into intact animals, a homogenous cytogenetic feature of subpopulation persisted during 2 passages only. Kinetics studies of a subvariance of the Ehrlich-I.Ch.Ph. tumor containing "A1"-cells show that the tumor growth rate and grade of malignancy slightly differ from those seen in the controls.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy* / Q000235:genetics; D005819:Genetic Markers / Q000187:drug effects; D005947:Glucose / Q000627:therapeutic use*; D007552:Isotonic Solutions; D051379:Mice; D009368:Neoplasm Transplantation; D011110:Polymorphism, Genetic / Q000187:drug effects*; D012641:Selection, Genetic; D012965:Sodium Chloride / Q000627:therapeutic use; D013386:Succinates / Q000627:therapeutic use*; D013997:Time Factors
D005819:Genetic Markers; D007552:Isotonic Solutions; D013386:Succinates; D012965:Sodium Chloride; D005947:Glucose
Polimorfizm populiatsii opukholevykh kletok i selektivnye protsessy. III. Izmenenie sootnosheniia subpopuliatsiĭ opukholevykh kletok astsitnogo shtamma Erlikha-TKhF pod vliianiem gliukozy i suktsinata natriia.