Liver injury and multiple drug therapy.
Analysis of the drugs used at the time of hepatic injury was carried out in a group of patients consecutively admitted to medical wards during a 10 years period (1965-1975). One drug was the possible cause in 26% of the patients and 74% of them were treated with multiple drug therapy. The most common drugs associated with liver damage have been sulphonamides, oral contraceptives, nitrofurantoin, methyldopa and phenothiazine derivatives.
D000328:Adult; D000368:Aged; D056486:Chemical and Drug Induced Liver Injury / Q000453:epidemiology / Q000209:etiology*; D004359:Drug Therapy, Combination / Q000009:adverse effects*; D005260:Female; D005387:Finland; D006801:Humans; D008297:Male; D008875:Middle Aged