Mathematical model of the proliferation cycle of lymphoblastic leukemia cells.
In the paper a system of equations is described, which enables computation of the mean number of leukemic cells in the blood as a function of time. After formulation of the problem in the form of cybernetical model, the equations are derived. Then the results of modeling obtained with the aid of a digital computer are described. The paper concludes with short summary.
D002453:Cell Cycle; D003201:Computers; D003491:Cybernetics; D006801:Humans; D007700:Kinetics; D007945:Leukemia, Lymphoid / Q000473:pathology*; D008433:Mathematics; D008954:Models, Biological; D011336:Probability; D013997:Time Factors