Serum xanthine dehydrogenase of carbon tetrachloride-induced hepatotoxicity in alloxan-diabetic rats.
Xanthine dehydrogenase activity was determined in blood serum of rats in which diabetes had been induced by alloxan administration. The results show that there is no statistical significance in the difference found for normal and diabetic rats. Alloxan produced an inhibition in the enzyme activity in animals in which a carbon tetrachloride hepatotoxicity had been induced.
D000496:Alloxan / Q000494:pharmacology; D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000150:complications / Q000201:enzymology*; D003921:Diabetes Mellitus, Experimental / Q000150:complications / Q000201:enzymology*; D007658:Ketone Oxidoreductases / Q000097:blood*; D007700:Kinetics; D008099:Liver / Q000473:pathology*; D008297:Male; D051381:Rats; D014968:Xanthine Dehydrogenase / Q000097:blood*
D000496:Alloxan; D014968:Xanthine Dehydrogenase; D007658:Ketone Oxidoreductases