title: Minor salivary gland calculi. A clinicopathologic study of forty-seven new cases.
abstract: An analysis of forty-seven previously unreported cases of minor salivary gland calculi revealed that they were usually solitary, firm, freely movable, small masses. Also, we noted that these calculi exhibited a striking predilection for the upper lip and buccal mucosa of adults. The organic matrix of all calculi was similar; however, the amount of mineralized material was variable. A variety of types of epithelial metaplasia was noted in the pericalcular ducts, with the most common type being squamous-cell metaplasia. Chronic periductal and lobular inflammation in addition to duct ectasia were common findings. The cause of minor salivary gland calculi is not known; however, local factors, such as duct morphology or biochemical alterations, or both, may be involved.
mesh_terms: D000328:Adult; D000368:Aged; D003116:Color; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D008046:Lip / Q000473:pathology; D008297:Male; D008875:Middle Aged; D008903:Minerals; D009061:Mouth Mucosa / Q000473:pathology; D012465:Salivary Duct Calculi / Q000378:metabolism / Q000473:pathology*; D012469:Salivary Glands / Q000473:pathology; D012470:Salivary Glands, Minor / Q000473:pathology; D012793:Sialadenitis / Q000473:pathology
chemical_list: D008903:Minerals