Monosomy 14, monosomy 22 and 13q--three chromosomal abnormalities observed in cells of two malignant mesotheliomas studied by banding techniques.
Two malignant mesotheliomas were studied by banding techniques. Both neoplasms had a hypodiploid stemline. Five and eight marker chromosomes, respectively, were included in the stemline karyotypes. Monosomy 14, monosomy 22 and a No. 13 with an interstitial long-arm deletion were deviations found in both neoplasms. In addition, closely located regions in No. 1 and No. 3 were involved in both tumors in the formation of other marker types with dissimilar morphology.
D000328:Adult; D000368:Aged; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002901:Chromosomes, Human, 13-15; D002904:Chromosomes, Human, 21-22 and Y; D006801:Humans; D007621:Karyotyping; D008297:Male; D008654:Mesothelioma / Q000235:genetics*; D010534:Peritoneal Neoplasms / Q000235:genetics*; D010997:Pleural Neoplasms / Q000235:genetics*