Chromosomal marker 20q- in cases of osteomyelosclerosis and CML.
Two male patients with myeloproliferative disorders (osteomyelosclerosis in one and CML in the other) were found to have a chromosomal marker 20q- in blood cells (unstimulated short time cultures). Marked erythropoietic disturbances were not revealed in these cases. The specificity of the 20q- marker for red cell disorders is discussed.
D000368:Aged; D002872:Chromosome Deletion; D002903:Chromosomes, Human, 19-20; D004920:Erythropoiesis; D006801:Humans; D007951:Leukemia, Myeloid / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000235:genetics*