title: Paternal age effect in fibrodysplasia ossificans progressiva.
abstract: Analysis by the method of Smith (1972) of birth order and parental age data collected from 38 of 42 patients with fibrodysplasia ossificans progressive shows a significant paternal age effect. This finding among the sporadically occurring cases would support the proposition that this condition usually arises as a new dominant mutation.
mesh_terms: D000328:Adult; D001722:Birth Order; D005260:Female; D005356:Fibromyalgia / Q000235:genetics*; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D008423:Maternal Age; D008875:Middle Aged; D009154:Mutation; D009221:Myositis Ossificans / Q000235:genetics*; D010331:Paternal Age; D013577:Syndrome