title: The effect of electrical stimulation on the experimentally denervated rat muscle.
abstract: The m. quadriceps of white rats was electrically stimulated after nerve crush and after nerve section. Electrically stimulated muscles showed fewer central nuclei and a greater number of necrotic single fibres. The demonstration of motor endplates could not give a reliable indication of the onset of reinnervation. The various results show the importance of the trophic influence of the nerve and raise the suspicion that electrical stimulation has a retarding effect on the atrophy but also on regeneration of the fibres. After 7 weeks the unstimulated muscles show a greater degree of regeneration than the stimulated ones.
mesh_terms: D000818:Animals; D004599:Electric Stimulation Therapy; D009121:Muscle Denervation; D009133:Muscular Atrophy / Q000628:therapy*; D009409:Nerve Crush; D009416:Nerve Regeneration; D051381:Rats