title: An unusual case of median cleft lip with orbital hypotelorism--a missing link in the classification.
abstract: De Myer (1963) classified median-facial anomalies into two groups: 1. Median cleft lip with orbital hypotelorism 2. Median cleft lip with orbital hypertelorism. The first group is characterised by median-cleft lip, absence of premaxilla, nasal skeleton, and crista galli. In addition, there is a holoprosencephaly which may involve the whole forebrain or a smaller part of the brain. In this group, the children die within the first year or during childhood and always suffer from mental retardation. In this report, we present a 12-year-old child with an unusual form of median cleft lip with hypotelorism without brain deformity.
mesh_terms: D002648:Child; D002675:Child, Preschool; D002971:Cleft Lip / Q000145:classification / Q000150:complications*; D004569:Electroencephalography; D005145:Face / Q000002:abnormalities; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008437:Maxilla / Q000002:abnormalities; D009666:Nose / Q000002:abnormalities; D009915:Orbit / Q000002:abnormalities*