Succinylacetone, a potent inhibitor of heme biosynthesis: effect on cell growth, heme content and delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D006418:Heme / Q000096:biosynthesis*; D006454:Hemoglobins / Q000096:biosynthesis; D006537:Heptanoates / Q000494:pharmacology*; D006538:Heptanoic Acids / Q000494:pharmacology*; D007651:Keto Acids / Q000494:pharmacology; D004915:Leukemia, Erythroblastic, Acute / Q000378:metabolism*; D007942:Leukemia, Experimental / Q000378:metabolism; D051379:Mice; D000623:Porphobilinogen Synthase / Q000037:antagonists & inhibitors*
D006454:Hemoglobins; D006537:Heptanoates; D006538:Heptanoic Acids; D007651:Keto Acids; D006418:Heme; C020804:succinylacetone; D000623:Porphobilinogen Synthase