Peripheral B- and T-lymphocyte counts in patients with sarcoma and breast carcinoma.
Peripheral B- and T-lymphocyte counts were studied in 50 patients before they received any therapy for their conditions: 16 had carcinoma of the breast; 8 soft tissue sarcoma; and 26, benign disease. Among 11 males, the six patients with advanced soft tissue sarcoma had significantly lower percentages of T lymphocytes than five patients with benign conditions. And six female patients with advanced breast cancers had significantly higher numbers of B lymphocytes than the 10 patients with early breast malignancies. Pertinent reports in the literature were reviewed and discussed. Presently, the clinical and prognostic values of quantitative study of T and B lymphocytes remain to be defined.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001402:B-Lymphocytes; D001943:Breast Neoplasms / Q000097:blood* / Q000473:pathology; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D012509:Sarcoma / Q000097:blood*; D012983:Soft Tissue Neoplasms / Q000097:blood*; D013601:T-Lymphocytes