Scanning electron microscopy of antibody-dependent cell-mediated cytotoxicity of Friend leukemia virus-infected spleen cells.
Friend leukemia virus (FLV) infected splenocytes treated with rabbit anti-FLV serum and subsequently incubated with splenic lymphocytes from non-immune Balb/c mice were examined by scanning electron microscopy. Villous-covered lymphocytes adherred to the tumor cells and induced surface blebs, numerous membrane pores and eventual tumor cell lysis.
D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity; D005622:Friend murine leukemia virus; D004915:Leukemia, Erythroblastic, Acute / Q000276:immunology; D007942:Leukemia, Experimental / Q000276:immunology* / Q000473:pathology; D008297:Male; D051379:Mice; D008855:Microscopy, Electron, Scanning; D013154:Spleen / Q000276:immunology / Q000473:pathology