Hemolysis in vitro by sorbose, sorbitol and xylitol.
L-sorbose, xylitol and sorbitol solutions (56 mM) were not hemolytic when incubated with erythrocytes of 30 healthy volunteers, 14 thalassemic heterozygotes and in 30 horses, 30 cows and 30 Osborne-Mendel rats. Lysis of dog erythrocytes was most pronounced when incubated with L-sorbose but was also significant in xylitol and sorbitol solutions.
D000818:Animals; D002417:Cattle; D004285:Dogs; D004912:Erythrocytes; D006461:Hemolysis / Q000187:drug effects*; D006736:Horses; D006801:Humans; D066298:In Vitro Techniques; D051381:Rats; D013012:Sorbitol / Q000494:pharmacology*; D013013:Sorbose / Q000494:pharmacology*; D013789:Thalassemia / Q000097:blood; D014993:Xylitol / Q000494:pharmacology*
D013012:Sorbitol; D013013:Sorbose; D014993:Xylitol