title: Do surgical packs cause peritoneal adhesions?
abstract: In spite of the growing variety of materials being used in the manufacture of intraabdominal packs (sponges), no data have been published on their adhesion-producing properties. We have shown that the Porton rat will reliably produce peritoneal adhesions in response to ischaemia and glove powder. In a randomized control trial using this rat model, we tested the adhesogenic potential of two commercially available surgical packs. Both brands of pack were shown to cause a significant incidence of postoperative peritoneal adhesions (P is less than 0.005), irrespective of whether the packs were used wet or dry. It is recommended that the adhesogenic potential of all products for use within the peritoneal cavity be established in an animal model prior to marketing.
mesh_terms: D000818:Animals; D001458:Bandages / Q000009:adverse effects*; D005260:Female; D008297:Male; D010532:Peritoneal Diseases / Q000209:etiology*; D051381:Rats; D000267:Tissue Adhesions