Osteogenic sarcoma in siblings.
A brother and sister with osteogenic sarcoma are reported. A review of the literature reveals thirty additional cases of osteogenic sarcoma in familial aggregation, sixteen of sibling relationship. Genetic and environmental etiologic factors of osteogenic sarcoma are discussed.
D000293:Adolescent; D001859:Bone Neoplasms / Q000175:diagnosis / Q000235:genetics*; D002648:Child; D005260:Female; D005266:Femoral Neoplasms / Q000175:diagnosis; D006801:Humans; D006811:Humerus; D008297:Male; D012516:Osteosarcoma / Q000175:diagnosis / Q000235:genetics*