A new method for the visualization of the epidermal Langerhans cell and its application on normal and allergic skin.
When skin specimens are exposed in vitro to L-dopa and catecholamines these substances accumulate in the Langerhans cells where they can be visualized with the histofluorescence method of Falck and Hillarp. Some methodological aspects are discussed and a preliminary study of Langerhans cells in contact allergy is reported.
D000818:Animals; D002395:Catecholamines / Q000378:metabolism; D003877:Dermatitis, Contact / Q000473:pathology; D000078404:Epidermal Cells; D006168:Guinea Pigs; D006801:Humans; D007801:Langerhans Cells / Q000166:cytology*; D007980:Levodopa / Q000378:metabolism; D008856:Microscopy, Fluorescence
D002395:Catecholamines; D007980:Levodopa