Thymoma immunological and ultrastructural characterization.
A 69-year-old man with a mediastinal mass was found to have atypical lymphoid cells in peripheral blood and bone marrow. Light and electron microscopic studies showed that the mediastinal mass was a thymoma. B- and T-cell differentiation and PHA responsiveness in the tumor and peripheral blood were consistent with T-cells. After excision of the tumor and a course of radiotherapy  the B/T ratio and PHA responsiveness in peripheral blood returned to normal while the atypical lymphocytes disappeared from circulation.
D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology; D001853:Bone Marrow / Q000648:ultrastructure; D001854:Bone Marrow Cells; D006801:Humans; D037102:Lectins / Q000494:pharmacology; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000648:ultrastructure*; D008297:Male; D008479:Mediastinal Neoplasms / Q000097:blood / Q000276:immunology* / Q000648:ultrastructure; D013601:T-Lymphocytes / Q000276:immunology; D013945:Thymoma / Q000097:blood / Q000276:immunology* / Q000648:ultrastructure
D037102:Lectins