[Role of an insoluble thymus fraction in the differentiation of T lymphocytes].
An insoluble thymic fraction, free of both thymocytes and thymic hormone, was injected intraperitoneally to C57B1/6 mice. Following this injection, marked changes were noted in thymocyte populations: these consisted mainly in a significant increase of subcapsular prothymocytes, peaking at day 7. These observations were made by histological examination and confirmed by a study of physical characteristics of thymocyte populations. The possibility that this insoluble thymic fraction might have a biologically active component responsible for prothymocytes recruitment is examined.
D000818:Animals; D002454:Cell Differentiation; D008566:Membranes / Q000502:physiology; D051379:Mice; D012995:Solubility; D013601:T-Lymphocytes / Q000166:cytology*; D013950:Thymus Gland / Q000166:cytology / Q000502:physiology* / Q000648:ultrastructure
Rôle d'une fraction thymique insoluble dans la différenciation des lymphocytes T.