title: Anterior uveitis in juvenile rheumatoid arthritis.
abstract: The ocular and systemic characteristics of 160 patients with anterior uveitis and seronegative juvenile rheumatoid arthritis are reviewed. Chronic uveitis occurred in 131 patients, 76% of whom were girls. Both eyes were involved in 70% of the cases. Band keratopathy occurred in 41% of the eyes, cataract in 42%, and secondary glaucoma in 19%. Only 11 patients had uveitis before the onset of arthritis. Notable correlations included a pauciarticular onset of arthritis in 95% of the patients, and positive tests for antinuclear antibody in 82%. Of 29 patients with acute anterior uveitis, 27 were boys. The inflammation responded well to therapy, and serious complications did not occur. At follow-up 21 patients had typical ankylosing spondylitis, and five had sacroiliitis. The incidence of positive results of tests for HLA-B27 antigen was 94%.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000974:Antibodies, Antinuclear / Q000032:analysis; D001171:Arthritis, Juvenile / Q000150:complications* / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004487:Edema / Q000150:complications; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007637:Keratoconjunctivitis / Q000150:complications; D008266:Macula Lutea; D008297:Male; D012164:Retinal Diseases / Q000276:immunology; D014605:Uveitis / Q000150:complications*
chemical_list: D000893:Anti-Inflammatory Agents; D000974:Antibodies, Antinuclear; D006680:HLA Antigens