Pseudo-Chediak-Higashi anomaly in promyelocytic leukaemia associated with intravascular coagulation.
Giant granules were present in the cytoplasm of marrow granulocytes and in abnormal immature leucocytes circulating in the blood of a patient with promyelocytic leukaemia associated with intravascular coagulation. These granules resembled those seen in Chediak-Higashi syndrome.
D001853:Bone Marrow / Q000473:pathology*; D002609:Chediak-Higashi Syndrome / Q000097:blood*; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000150:complications*; D005260:Female; D006098:Granulocytes / Q000648:ultrastructure; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000097:blood* / Q000150:complications; D007962:Leukocytes / Q000648:ultrastructure*; D008875:Middle Aged