Confirmation that neither phenotype nor hydroxylation of collagen is altered in overgrown gingiva from diphenylhydantoin-treated patients.
Collagens, solubilized by pepsin-digestion of diphenylhydantoin-induced overgrown gingiva, appeared similar to collagens solubilized from inflamed gingiva with regard to: ratio of type I to type III collagen, ratio of alpha1 to alpha2 of type I collagen, and degree of hydroxylation of type I collagen.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002845:Chromatography; D003094:Collagen / Q000302:isolation & purification / Q000378:metabolism*; D005881:Gingiva / Q000032:analysis; D005885:Gingival Hyperplasia / Q000139:chemically induced / Q000378:metabolism*; D005891:Gingivitis / Q000378:metabolism*; D006801:Humans; D006900:Hydroxylation; D006909:Hydroxyproline / Q000378:metabolism; D008239:Lysine / Q000378:metabolism; D008875:Middle Aged; D010641:Phenotype; D010672:Phenytoin / Q000009:adverse effects*; D011392:Proline / Q000378:metabolism
D010672:Phenytoin; D003094:Collagen; D011392:Proline; D008239:Lysine; D006909:Hydroxyproline