Aldosterone binding in bovine ciliary body.
The presence of aldosterone binding which was not identical with dexamethasone binding was verified in the ciliary body of the bovine eye in vitro. The site of aldosterone binding was presumably located in the non-pigmented layer of ciliary epithelium. Specific aldosterone binding was found also in lens epithelium but not in corneal epithelium. The finding of receptor-like aldosterone binding confirms the concept of possible mineralocorticoid-dependent active sodium transport through the ciliary and lens epithelium in the eye.
D000450:Aldosterone / Q000378:metabolism*; D000818:Animals; D001665:Binding Sites; D002417:Cattle; D002924:Ciliary Body / Q000378:metabolism*; D003907:Dexamethasone / Q000494:pharmacology; D004848:Epithelium / Q000378:metabolism; D007908:Lens, Crystalline / Q000378:metabolism
D000450:Aldosterone; D003907:Dexamethasone