title: Therapeutics of caries prevention--concepts and prospects.
abstract: Despite intensive research, water fluoridation and, where practiced, diet control, remain the most effective methods of preventing caries. In this paper, a number of approaches discussed appear to hold promise that they may enhance the caries preventive effect of fluoride, and others, when developed and applied, may hasten the day when dental caries will cease to be a public health problem.
mesh_terms: D000287:Administration, Topical; D000336:Aerosols; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D001428:Bacterial Vaccines / Q000627:therapeutic use; D003731:Dental Caries / Q000517:prevention & control*; D003733:Dental Caries Susceptibility; D003773:Dental Plaque / Q000382:microbiology / Q000517:prevention & control; D057487:Enzyme Therapy; D006801:Humans; D013295:Streptococcus mutans / Q000276:immunology; D013549:Sweetening Agents / Q000627:therapeutic use; D014611:Vaccination
chemical_list: D000336:Aerosols; D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D001428:Bacterial Vaccines; D013549:Sweetening Agents