title: Autologous blood transfusion during cardiac surgery. A re-evaluation of three methods.
abstract: The use of autologous blood transfusion to decrease blood bank requirements and improve coagulation parameters during cardiac surgery is still controversial. This study was undertaken to re-evaluate three methods of autologous blood transfusion. Before bypass, 13 to 15 percent of the patient's estimated blood volume was removed and stored with either CPD or heparin at room temperature and returned via a peripheral vein after bypass. All patients had significant abnormalities in their PTT, PT, and platelet counts after bypass. Heparinized autologous blood removed from the vena cava cannula was the only technique which significantly improved the PTT and platelet count. Total blood bank requirements were significantly less for the autologous blood groups than for controls. There was a saving of 18 percent in banked blood requirements. Fresh frozen plasma and platelets were not found to be routinely needed during cardiac surgery.
mesh_terms: D001772:Blood Cell Count; D001780:Blood Coagulation Tests; D001792:Blood Platelets; D001804:Blood Transfusion, Autologous / Q000379:methods*; D001810:Blood Volume; D006348:Cardiac Surgical Procedures; D001026:Coronary Artery Bypass; D005069:Evaluation Studies as Topic; D006350:Heart Valve Prosthesis; D006493:Heparin; D006801:Humans; D010949:Plasma; D011183:Postoperative Complications
chemical_list: D006493:Heparin