title: Genetic translocation in Staphylococcus aureus.
abstract: A 5.2-kilobase pair transposon, Tn551, has been found in Staphylococcus aureus, a Gram-positive bacterium. Initially detected on plasmid pI258, it undergoes rec-independent transposition to multiple chromosomal and plasmid sites, sometimes causing insertional inactivation. Unlike most other transposons, Tn551 undergoes apparently precise excision as a rule. The initial observation of Tn551 transition involved UV inactivation of the carrier plasmid; this would appear to be a general means of detecting transposable elements.
mesh_terms: D002872:Chromosome Deletion; D002874:Chromosome Mapping; D004352:Drug Resistance, Microbial; D004917:Erythromycin; D005796:Genes; D010957:Plasmids; D011815:R Factors; D011995:Recombination, Genetic; D013211:Staphylococcus aureus / Q000235:genetics*; D014178:Translocation, Genetic
chemical_list: D004917:Erythromycin