[Induction of anti-glomerular basement membrane antibodies in BN rats: genetic control].
Mercuric chloride induces anti-glomerular basement membrane antibodies in Brown Norway rats  (Ag B3) and not in Lewis rats (Ag B1). Studies on (Lewis X BN) F1 and F2 and with back-crosses (Lewis X BN) F1 X Lewis demonstrate a genetic control for this immune response. This genetic control probably depends on two non-linked, autosomal and dominant genes. One of these genes is linked to the major histocompatibility locus.
D000818:Animals; D000917:Antibody Formation; D001485:Basement Membrane / Q000276:immunology*; D007125:Immunogenetics; D007678:Kidney Glomerulus / Q000276:immunology*; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew
Induction d'anticorps ant-membrane basale glomérulaire (MBG) chez le rat Brown Norway: contrôle génétique de la réponse anticorps