title: Oestrus and fertility following progestagen treatment of mares showing clinical evidence of early pregnancy failure.
abstract: Of 383 mares showing clinical evidence of suspected early fetal resorption between 20 and 60 days after mating, 217 were treated with a single injection of 200 mg CAP (a synthetic progestagen); the remaining 166 mares served as untreated controls. Treatment had neither a beneficial nor a detrimental effect on the continuation of pregnancy. Conception rates following loss of the conceptus were higher in lactating than in non-lactating mares. No increase in number of twin or deformed foals was evident in the treated animals.
mesh_terms: D000818:Animals; D004971:Estrus / Q000187:drug effects*; D005260:Female; D005298:Fertility / Q000187:drug effects*; D005313:Fetal Death / Q000662:veterinary*; D005327:Fetal Resorption / Q000517:prevention & control / Q000662:veterinary*; D006734:Horse Diseases / Q000517:prevention & control*; D006736:Horses; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D045167:Progesterone Congeners / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D045167:Progesterone Congeners