[Immunopathogenetic aspects of chronic hepatitis].
In a short survey aspects to the immunopathogenesis of chronic hepatitides are explained. Hereby, partly critically, humoral and cellular immunophenomena are discussed, furthermore, the author deals with genetic factors, viruses and drugs as a cause of autoimmune hepatitides. Finally a simple working hypothesis to the pathogenesis is formulated and it is tried to classify the chronic aggressive hepatitis into six sub-groups on the basis of immunological, clinical and biochemical criteria: 1. much HBAg-associated, 2. lupoid, 3. drug-induced, 4. autoimmune cholostatic mixed form, 5. much associated with Ak to endoplasmatic reticulum and 6. undefined.
D000974:Antibodies, Antinuclear / Q000302:isolation & purification; D000917:Antibody Formation; D001323:Autoantibodies / Q000302:isolation & purification; D001327:Autoimmune Diseases / Q000150:complications; D002908:Chronic Disease; D005260:Female; D006680:HLA Antigens / Q000302:isolation & purification; D006505:Hepatitis / Q000209:etiology / Q000276:immunology*; D006511:Hepatitis B Antigens / Q000302:isolation & purification; D006801:Humans; D007136:Immunoglobulins / Q000302:isolation & purification; D008103:Liver Cirrhosis / Q000276:immunology; D008297:Male
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D006680:HLA Antigens; D006511:Hepatitis B Antigens; D007136:Immunoglobulins
Aspekte zur Immunpathogenese chronischer Hepatitiden