Significant hormonal changes in patterns of lipid granules in vaginal exfoliated cells.
In vaginal exfoliative cytology, the routine Papanicolaou and Shorr's staining procedures do not reliably indicate the post-ovulatory phase. An experimental study of 100 female albino rats and a clinical study of 190 women was initiated to establish an easier method for identifying the post-ovulatory phase. It was found that the appearance of intracytoplasmic lipid granules in vaginal cells stained by Oil Red 0 may serve as a sensitive indicator of the post-ovulatory phase.
D000818:Animals; D003276:Contraceptives, Oral / Q000494:pharmacology; D003594:Cytoplasmic Granules / Q000032:analysis*; D004971:Estrus; D005260:Female; D006801:Humans; D008055:Lipids; D008598:Menstruation; D011085:Polycystic Ovary Syndrome / Q000473:pathology; D011247:Pregnancy; D051381:Rats; D014621:Vagina / Q000648:ultrastructure*
D003276:Contraceptives, Oral; D008055:Lipids