Epidermal growth factor stimulates secretion of human chorionic gonadotropin by cultured human choriocarcinoma cells.
Epidermal growth factor (EGF) binds to JEG-3 cells, a tissue culture line of human choriocarcinoma. EGF also stimulates secretion of human chorionic gonadotropin (hCG) and to a lesser extent the secretion of free hCG-alpha.
D002478:Cells, Cultured; D002822:Choriocarcinoma / Q000378:metabolism*; D006063:Chorionic Gonadotropin / Q000378:metabolism*; D003470:Culture Media; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D005260:Female; D006801:Humans; D010446:Peptide Fragments / Q000378:metabolism; D010455:Peptides / Q000494:pharmacology*; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000378:metabolism*
D006063:Chorionic Gonadotropin; D003470:Culture Media; D010446:Peptide Fragments; D010455:Peptides; D004815:Epidermal Growth Factor