Embryonic mouse thymus development: stem cell entry and differentiation.
The entry and subsequent division and differentiation of blood-borne stem cells within the embryonic thymus has been studied in a system where the inflowing cells were either chromosomally or antigenically marked. H-2 positive stem cells enter the thymus within 5 days of grafting but may wait for up to 14 days before proliferating to give rise to Thy-1 positive thymocytes.
D000818:Animals; D000941:Antigens; D002454:Cell Differentiation; D002875:Chromosomes; D003602:Cytotoxicity, Immunologic; D006412:Hematopoietic Stem Cells / Q000502:physiology*; D051379:Mice; D008808:Mice, Inbred CBA; D009929:Organ Size; D013601:T-Lymphocytes; D013950:Thymus Gland / Q000196:embryology*
D000941:Antigens