Pain-induced alterations in the individual non-esterified fatty acids in serum.
Changes of individual non-esterified fatty acids in serum were studied in 7 metabolically healthy patients, suffering from idiopathic trigeminal neuralgia, who underwent electrocoagulation of gasserian ganglion under neurolepthypalgesia. The mean concentration of fatty acids increased by about 40% during the strong surgical pain stimulus. The increased lipolysis affected all individual fatty acids in proportion to the ratio of their presence in adipose tissue. The mechanism of pain-induced activation of lipase and possible consequences of alterations in individual non-esterified fatty acids are discussed.
D000328:Adult; D000368:Aged; D004564:Electrocoagulation; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D005260:Female; D006801:Humans; D008053:Lipid Mobilization; D008297:Male; D008875:Middle Aged; D012668:Trigeminal Ganglion / Q000601:surgery; D014277:Trigeminal Neuralgia / Q000097:blood* / Q000601:surgery
D005230:Fatty Acids, Nonesterified