title: Loss and recovery of trabecular bone in the distal radius following fracture--immobilization of the upper limb in children.
abstract: Computed tomography of the human radius is performed using a special purpose scanning device which incorporates a radionuclide (125I) as radiation source. Parameters decribing the trabecular bone and the compact bone are determined at a distal and a diaphyseal measuring site respectively. Using this measurement technique changes in bone mineralization in the radius were studied in a group of 23 children following immobilization of an upper limb for fracture healing. An immobilization period of between three to six weeks resulted in a reduction of the relevant parameter value of up to 44% (mean 16%) in the distal part of the radius, whereas no significant change could be seen in the diaphyseal part of the same bone. Rapid remineralization of trabecular bone is indicated by the increase of the corresponding parameter value at a rate of up to several percent per week. However, in some of the patients studied complete normalization was not attained during the first six months following cast removal.
mesh_terms: D001861:Bone Regeneration; D001862:Bone Resorption; D002648:Child; D005260:Female; D005592:Fracture Fixation; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D011884:Radius / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011885:Radius Fractures / Q000000981:diagnostic imaging / Q000503:physiopathology*; D013997:Time Factors; D014055:Tomography, Emission-Computed; D014458:Ulna Fractures / Q000000981:diagnostic imaging / Q000503:physiopathology
chemical_list: D007457:Iodine Radioisotopes