Catecholamine levels in the whole brain and the probability of memory formation are not related.
Amnesia was induced with reserpine or was blocked with 1-dopa and 5-hydroxytrptophan before or after passive avoidance training in mice. The levels of dopamine and norepinephrine in the whole brain were measured in corresponding groups with gas chromatography-mass spectrometry. No correlation was found between retention and the levels of these catecholamines in the brain.
D006916:5-Hydroxytryptophan / Q000494:pharmacology; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology; D001923:Brain Chemistry / Q000187:drug effects; D002395:Catecholamines / Q000032:analysis / Q000502:physiology*; D004298:Dopamine / Q000032:analysis; D007980:Levodopa / Q000494:pharmacology; D008297:Male; D008568:Memory / Q000502:physiology*; D051379:Mice; D009638:Norepinephrine / Q000032:analysis; D012110:Reserpine / Q000494:pharmacology; D013997:Time Factors
D002395:Catecholamines; D007980:Levodopa; D012110:Reserpine; D006916:5-Hydroxytryptophan; D004298:Dopamine; D009638:Norepinephrine