Symposium on membrane markers and antigens of human lymphocytes and leukemic cells.
B lymphocytes, mediators of humoral immunity, carry easily detectable SIg, form rosettes with RBC coated with IgM and complement (EAC rosetting) and bind aggregated Ig (Fc receptor activity). Human T lymphocytes, mediators of cellular immunity, lack a specific antigen found on mice T lymphocytes (theta antigens). They form spontaneous (non-immune) rosettes with SRCB (E rosetting) and they are identified by labelling or cytotoxicity tests wtih heterologous antisera. Apart from B and T lymphocytes, a third population of lymphoid cells carrying no detectable surface markers have been identified by various methods (Null cells).
D001402:B-Lymphocytes / Q000276:immunology; D001666:Binding Sites, Antibody; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D011947:Receptors, Antigen, B-Cell / Q000276:immunology; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology
D007141:Immunoglobulin Fc Fragments; D011947:Receptors, Antigen, B-Cell