Retrospective tests of B-cold lymphocytotoxins and transplant survival at a single center.
Sera from 203 recipients prior to transplantation were examined against a panel of 30 T and B lymphocytes at 5 degrees C and 37 degrees C. Those patients classified as having B-cold cytotoxins only had higher 1-year transplant survival rates from cadaver donors (82%) than patients with no antibodies (58%) or patients with antibodies reactive to T and B lymphocytes in the warm (37%). These results based on transplants from a single center confirm earlier studies derived from patients in 27 centers.
D000961:Antilymphocyte Serum / Q000627:therapeutic use*; D001402:B-Lymphocytes / Q000276:immunology*; D003080:Cold Temperature; D003450:Cryoglobulins / Q000276:immunology; D006085:Graft Survival; D006801:Humans
D000961:Antilymphocyte Serum; D003450:Cryoglobulins