[Experimental study of bacteremia and its role in the pathogenesis of dysentery].
In experiments on white mice pathophysiological, bacteriological, histological and immunofluorescent methods of investigation were used; it was shown that Sonne dysentery bacteria were capable during a short period of time to penetrate into the blood from the lumen of the stomach and the small intestine and moreover to deposit in the cells of the mucosa of the said organs. Into the large intestine the pathogen penetrates from the above situated departments of the intestine, which was most often observed in impairment of the evacuatory function of the stomach; moreover, the possibility of elimination of Sonne Shigella, as well as products of their desintegration, by the large intestine wall was shown. Bacteriemia is a short-term phenomenon and could be identified at early periods following infection, which may account for the fact of rare identification of Shigella in the blood of patients with dysentery.
D000818:Animals; D004405:Dysentery, Bacillary / Q000150:complications / Q000382:microbiology / Q000473:pathology*; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology*; D007413:Intestinal Mucosa / Q000382:microbiology / Q000473:pathology*; D051379:Mice; D018805:Sepsis / Q000209:etiology; D012764:Shigella sonnei / Q000302:isolation & purification
Eksperimental'noe izuchenie bakteriemii i ee znachenie v patogeneze dizenterii