[Spheroplast bacteriocin from strains of the causative agent of pseudotuberculosis and its identification by the antibacterial activity spectrum and the morphology of the inhibition zones].
Capacity for production of bactericin was found in the spheroplasts of the strains of the rodent pseudotuberculosis microbe. The author named it as pseudotuberculocin. The bacteriocin production was not detected in the initial strains of the pseudotuberculosis microbe. Pseudotuberculocin differed in the antibacterial spectrum and morphology of the growth inhibition zones formed on the plates with the indicator strains from the pesticins produced by the strains of the plaque microbe of the marmot and sandword varieties respectively and the cultures of the plaque microbe from the Transcaucasian Upland, as well as from pesticins of the spheroplasts of these strains. Production of a pesticin differing from pesticins of the rod-like forms of these strains by an ability to inhibit the growth of the homologous indicators was shown in the spheroplasts of the plaque microbe of the marmot and sandword varieties. Sensitivity of the plaque microbe strains of the marmot and sandword varieties to the pesticins of the plaque microbe strains and pseudotuberculocin was noted. With an account of the difference in the activity of the tested pesticins and pseudotuberculocin against the strains of the Frederic collection it is recommended to use this property for identifications of pesticins and pseudotuberculocin.
D000818:Animals; D000898:Antibiosis / Q000187:drug effects*; D001430:Bacteriocins / Q000096:biosynthesis* / Q000302:isolation & purification / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D012376:Rodent Diseases / Q000382:microbiology; D012377:Rodentia; D013104:Spheroplasts / Q000378:metabolism*; D015007:Yersinia / Q000378:metabolism*; D015009:Yersinia Infections / Q000382:microbiology; D015010:Yersinia pestis / Q000378:metabolism
D001430:Bacteriocins
Bakteriotsin sferoplastov shtammov vozbuditelia psevdotuberkuleza i ego identifikatsiia po spektru antibakterial'noĭ aktivnosti i morfologii zon ingibitsii.