High resolution crystal structures of yeast hexokinase complexes with substrates, activators, and inhibitors. Evidence for an allosteric control site.
D000227:Adenine Nucleotides / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000495:Allosteric Site; D055598:Chemical Phenomena; D002621:Chemistry; D003460:Crystallization; D004789:Enzyme Activation; D005944:Glucosamine / Q000031:analogs & derivatives / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006593:Hexokinase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D008958:Models, Molecular; D008968:Molecular Conformation; D012441:Saccharomyces cerevisiae / Q000201:enzymology*; D013431:Sulfates / Q000378:metabolism
D000227:Adenine Nucleotides; D013431:Sulfates; D000255:Adenosine Triphosphate; D006593:Hexokinase; D005947:Glucose; D005944:Glucosamine