Morphological identification of alpha-1-antitrypsin in pulmonary macrophages.
Pulmonary macrophages, as seen in the routine sputum samples obtained from smokers, reveal bipolar orangophilic spurs. By use of histochemical and immunofluorescence techniques, these spurs have been found to contain alpha-1-antitrypsin. Morphological localization of this substance within the pulmonary macrophages may be significant.
D006651:Histocytochemistry; D006801:Humans; D008168:Lung / Q000166:cytology; D008173:Lung Diseases, Obstructive / Q000473:pathology*; D008264:Macrophages / Q000032:analysis* / Q000473:pathology; D012907:Smoking / Q000473:pathology; D013183:Sputum / Q000166:cytology*; D000515:alpha 1-Antitrypsin / Q000032:analysis*
D000515:alpha 1-Antitrypsin