The role of cardiovascular hemodynamics and liver histology in evaluating bleeding cirrhotic patients.
Preoperative cardiovascular hemodynamics and percutaneous liver biopsies were used to evaluate the pathophysiologic factors determining the operative prognosis of patients with cirrhotic liver disease and bleeding esophageal varices. These studies confirm the observations of Siegel that the greater the magnitude of the peripheral abnormalities in vascular tone and oxygen consumption the better must be the capability of the ventricular function, if the cirrhotic is to survive emergency or urgent portal decompressive surgery. These studies also show that the cardiovascular hemodynamics are directly correllated with the nature and degree of the abnormalities in the liver biopsy, and that pathologic and physiologic features of this disease which impact on surgical prognosis can be expressed through the easily obtained Survival Index. Bleeding cirrhotic patients with poor quality hemodynamics and poor histologic characteristics should be treated non operatively, since the operative mortality appears greater than that produced by a strategy of medical supportive therapy and delayed surgery if stabilization occurs.
D001707:Biopsy, Needle; D002302:Cardiac Output; D004630:Emergencies; D004932:Esophageal and Gastric Varices / Q000175:diagnosis* / Q000601:surgery; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis; D006439:Hemodynamics; D006801:Humans; D008099:Liver / Q000473:pathology*; D008103:Liver Cirrhosis / Q000175:diagnosis* / Q000601:surgery; D010101:Oxygen Consumption; D011379:Prognosis; D014655:Vascular Resistance