title: Genetic locus (ompB) affecting a major outer-membrane protein in Escherichia coli K-12.
abstract: Three multiply colicin-tolerant mutants in Escherichia coli K-12 from the TolIV, TolXIV, and TolXV phenotypic groups, all lacking or having only trace amounts of protein 1, a major outer-membrane protein, were mapped by Hfr crosses, and the position on the chromosome was confirmed by cotransduction with nearby markers. The mutations were located near malQP in the 74-min region of the E. coli chromosome. This locus is designated ompB, and analysis of data from two three-point crosses determined the linear sequence of genes to be aroB-ompB-malQP-glpD.
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis / Q000235:genetics*; D002473:Cell Wall / Q000378:metabolism; D002874:Chromosome Mapping; D003087:Colicins / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D005796:Genes; D009154:Mutation; D014161:Transduction, Genetic
chemical_list: D001426:Bacterial Proteins; D003087:Colicins