[Colony-stimulating factor (CSF) and granulopoietic activity (GA) in various mouse organs].
The colony stimulating factor and granulopoietic activity were determined in the homogenates of mouse kidney, liver, spleen and bone marrow. The activity of CSF and GA were highest in the kidney. The homogenate of this organ was fractionated then by ultracentrifugation. The distribution of CSF and GA in subcellular fractions and homogenates may suggest that kidney cells are the source of a substance causing, both, colony stimulation and granulopoietic activity.
D000818:Animals; D001853:Bone Marrow / Q000502:physiology / Q000648:ultrastructure; D003115:Colony-Stimulating Factors / Q000378:metabolism*; D006410:Hematopoiesis; D007668:Kidney / Q000502:physiology / Q000648:ultrastructure; D008099:Liver / Q000502:physiology / Q000648:ultrastructure; D008297:Male; D051379:Mice; D013154:Spleen / Q000502:physiology / Q000648:ultrastructure
D003115:Colony-Stimulating Factors
Czynnik pobudzajacy wzrost kolonii granulocytów (CSF) i aktywność granulopoetyczna (GA) w tkankach i narzadach myszy.