Bone disease, hypophosphatemia and hyperparathyroidism after renal transplantation.
Long-term survivors after renal transplantation (RT) show: 1) decreased s-phosphorus 2) increased s-PTH 3) no correlation between s-PTH and s-phosphorus 4) increased amount of non-mineralized bone (osteomalacia), inversely correlated to s-phosphorus 5) decreased amount of trabecular bone (osteopenia) in RT patients with aseptic necorsis of bone.


CONCLUSIONS
aseptic necrosis of bone after RT is mainly due to osteoid-induced osteopenia, perhaps aggravated by hypophosphatemic osteomalacia.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001847:Bone Diseases / Q000097:blood / Q000209:etiology*; D001842:Bone and Bones / Q000473:pathology; D002118:Calcium / Q000097:blood; D003404:Creatinine / Q000097:blood; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications*; D007674:Kidney Diseases / Q000097:blood; D016030:Kidney Transplantation; D008875:Middle Aged; D010015:Osteolysis, Essential / Q000097:blood; D010018:Osteomalacia / Q000097:blood; D010281:Parathyroid Hormone / Q000097:blood; D010710:Phosphates / Q000097:blood*; D014184:Transplantation, Homologous
D010281:Parathyroid Hormone; D010710:Phosphates; D003404:Creatinine; D002118:Calcium