[Relation of pharmacokinetics and toxicity of methotrexate at high dose].
D000328:Adult; D000368:Aged; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage* / Q000627:therapeutic use / Q000633:toxicity; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy*; D013763:Tetrahydrofolates / Q000627:therapeutic use*
D013763:Tetrahydrofolates; D002955:Leucovorin; C005984:5-methyltetrahydrofolate; D008727:Methotrexate
Rapporti fra farmacocinetica e tossicità del metotressato ad alta dose.