Polymorphic tetrameric superoxide dismutase in the pike Esox lucius L. (Pisces; Esocidae).
1. Heart muscle extracts of northern pike from Lake Malaren in Sweden exhibited two electophoretic types of superoxide dismutase, one of which was identified as the cytoplasmic enzyme (s-SOD) and the other as the mitochondrial form (m-SOD). 2. Individual analysis of 51 pike indicated that s-SOD was invariant while m-SOD displayed a pattern of variation which was explicable by a single-locus polymorphism. 3. The observed m-SOD phenotype patterns suggested that the enzyme is a tetramer. This interpretation is supported by in vitro molecular hybridization studies.
D000818:Animals; D003593:Cytoplasm / Q000201:enzymology; D004592:Electrophoresis, Starch Gel; D008929:Mitochondria, Heart / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology*; D010641:Phenotype; D011110:Polymorphism, Genetic; D012487:Salmonidae / Q000235:genetics / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000032:analysis* / Q000235:genetics
D013482:Superoxide Dismutase