title: [Gluing with fibrin in corneal surgery. An experimental study (author's transl)].
abstract: Penetrating corneal incisions of various sizes and forms were microsurgically glued onto 48 rabbit eyes by means of fibrinogen-plasma cryoprecipitate with or without 10x0 nylon sutures. Linear or curved penetrating corneal cuts up to 4 mm in length could be immediately closed water tight by pure gluing and without development of anterior synechiae. The suturing of oblique cuts may prove problematic. The more oblique such cuts were, the better the results they yielded after gluing. In cases of linear penetrating corneal incisions exceeding 4 mm in length, and in star-shaped wounds with radiants over 3 mm in length, anterior synechiae could only be avoided by application of additional sutures. Pure or additional gluing of corneal penetrating cuts accelerated wound healing, but was followed by broader scars than after pure suturing. Hence, the gluing of certain types of penetrating corneal wounds by means of fibrin can be applied only as an auxiliary procedure to microsurgical wound closure with sutures.
mesh_terms: D000818:Animals; D003315:Cornea / Q000601:surgery*; D005260:Female; D005340:Fibrinogen; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008722:Methods; D011817:Rabbits; D014014:Tissue Adhesives; D014945:Wound Healing
chemical_list: D014014:Tissue Adhesives; D005340:Fibrinogen
vernacular_title: Fibrinklebung in der Hornhautchirurgie. Eine experimentelle Studie.