title: [Salmonella typhimurium as a test system for detecting the mutagenic activity of environmental pollutants. I. The mutagenic action of heavy metal salts in in vivo and in vitro systems without metabolic activation].
abstract: The work presents the data on mutagenic effects of heavy metal salts (Zn and Cd) on Salmonella typhimurium test strains using mutagenicity test in vitro without metabolic activation and host-mediated assay. The techniques used enabled to determine also the types of mutations arising from the exposure to ZnCl2 and CdCl2.
mesh_terms: D000818:Animals; D002104:Cadmium / Q000009:adverse effects; D002712:Chlorides; D004785:Environmental Pollutants / Q000009:adverse effects*; D066298:In Vitro Techniques; D008670:Metals / Q000009:adverse effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009153:Mutagens; D009154:Mutation / Q000187:drug effects; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics*; D015032:Zinc / Q000009:adverse effects
chemical_list: D002712:Chlorides; D004785:Environmental Pollutants; D008670:Metals; D009153:Mutagens; D002104:Cadmium; D015032:Zinc
vernacular_title: Salmonella typhimurium--test-sistema dlia vyiavleniia mutagennoĭ aktivnosti zagriazniteleĭ okruzhaiushcheĭ sredy. Soobshchenie I. Mutagennoe deĭstvie soleĭ tiazhelykh metallov v sistemakh in vivo i in vitro bez metabolicheskoĭ aktivatsii.