[The psychotropic effect of beclamid (author's transl)].
60 boys and girls between 6 and 14 years with the symptoms "psychomotoric unrest", "disturbance of behavior" and "disturbed concentration" with and without epilepsy were treated and observed in hospital during a period of 8 weeks. Group I (20 patients) was given Beclamid, 3--6 tablets a day according to weight. Group II (20 patients) was given placebos in the same dosage. Group III (20 patients) was given Beclamid during 4 weeks and placebo for the following 4 weeks. Compared with the placebo groups the influence on concentration, memory and skill was significantly better after the application of Beclamid. The extent of the improvement depended on the period of medication. The Beclamid-group could be guided more easily, showed a better sense for cooperation and turned out to be more accessable to pedagogic methods. This positive psychotropic effect again increased with the period of medication. The (positive) influence on behaviour also affected the effciency at shcool and learning. Neither a sedative nor other side effects could be seen.
D000293:Adolescent; D000588:Amines / Q000627:therapeutic use*; D001596:Benzylamines / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002653:Child Behavior Disorders / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006948:Hyperkinesis / Q000188:drug therapy; D008297:Male; D008568:Memory / Q000187:drug effects; D008606:Mental Processes / Q000187:drug effects; D010919:Placebos; D011422:Propionates / Q000009:adverse effects / Q000627:therapeutic use*; D011596:Psychomotor Disorders / Q000188:drug therapy*; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use*
D000588:Amines; D001596:Benzylamines; D010919:Placebos; D011422:Propionates; D011619:Psychotropic Drugs
Die psychotrope Wirkung von Beclamid