title: The vascular supply of the endolymphatic sac.
abstract: The vascular anatomy of the endolymphatic sac in guinea pigs was examined following intravascular injection of silicone rubber (Microfil). Methacrylate resin of low viscosity (Mercox) was used to obtain vascular corrosion casts for scanning electron microscopy, which allowed more accurate differentiation between arteries and veins. The extensive vascular system around the sac comprises both arteries and veins, as well as lymphatic vessels. The arterial supply is derived mainly from the posterior meningeal artery in the posterior cranial fossa. In some cases a small artery also leads to the sac from the posterior vestibular artery in the labyrinth (in 7 of the 35 animals investigated). It courses together with the vein of the vestibular aqueduct along the walls of the endolymphatic duct. The blood is drained over the intermediate portion of the endolymphatic sac, which becomes lodged in a rich meshwork of capillaries, venules, veins and a few small arteries. A few venous trunks from both sac walls fuse with the vein of the vestibular aqueduct, which drains blood from the vestibule to the sigmoid sinus. Scanning electron microscopy also revealed numerous anastomosing vessels within bone channels with adjacent bone marrow sinusoids, which also probably contribute to the vascular supply of the endolymphatic sac.
mesh_terms: D000818:Animals; D002196:Capillaries / Q000648:ultrastructure; D007758:Ear, Inner / Q000033:anatomy & histology / Q000098:blood supply*; D004712:Endolymphatic Sac / Q000098:blood supply* / Q000166:cytology / Q000648:ultrastructure; D006168:Guinea Pigs; D006801:Humans; D008208:Lymphatic System / Q000033:anatomy & histology; D008576:Meningeal Arteries / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D012826:Silicone Elastomers; D014699:Venules / Q000648:ultrastructure; D014722:Vestibule, Labyrinth / Q000033:anatomy & histology
chemical_list: D012826:Silicone Elastomers