Endogenous Nocardia endophthalmitis: report of a case in a patient treated for lymphocytic lymphoma.
A patient with pulmonary, cerebral, and intraocular nocardiosis is reported. The intraocular disease was first recognized at autopsy. Only 7 patients with intraocular nocardiosis have been described previously. The intraocular lesions were central and paracentral, and the distribution resembled those described in 5 of the previous patients with metastatic intraocular disease. The ocular histology differed from those cases previously reported in that a granulomatous reaction accompanied the suppurative component. Malignant lymphoma treated with radiation therapy, cytotoxic drugs, and steroids formed the background against which the disease occurred in this patient.
D000368:Aged; D001922:Brain Abscess / Q000209:etiology; D002825:Chorioretinitis / Q000209:etiology* / Q000473:pathology; D005123:Eye / Q000473:pathology; D005260:Female; D006258:Head and Neck Neoplasms / Q000150:complications / Q000628:therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008169:Lung Abscess / Q000209:etiology; D008223:Lymphoma / Q000150:complications / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D009617:Nocardia Infections / Q000209:etiology* / Q000473:pathology; D009616:Nocardia asteroides
D007166:Immunosuppressive Agents