Nasal polyps treated by beclomethasone nasal aerosol.
A double-blind cross-over study of the effect of insufflation of beclomethasone dipropionate 400 microgram per day for four weeks showed favourable results, as verified statistically, concerning nasal blockage at the end of the treatment period. Rhinomanometry also showed that the nasal patency was significantly improved during the beclomethasone period. There was also a tendency, though not statistically significant, for nasal secretion to react favourable. The polyps did not disappear during the active treatment period and short-term treatment with beclomethasone aerosol can thus only be used as an adjuvant to other models of therapy, whether medical or surgical, in nasal polyps. No clinical side-effects of any importance were observed during the study.
D000281:Administration, Intranasal; D000328:Adult; D000336:Aerosols; D000368:Aged; D000402:Airway Obstruction / Q000175:diagnosis; D001507:Beclomethasone / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005069:Evaluation Studies as Topic; D006801:Humans; D008365:Manometry; D008875:Middle Aged; D009298:Nasal Polyps / Q000188:drug therapy*
D000336:Aerosols; D001507:Beclomethasone