[The protein constituents of human bronchial washings. Their relationship to the defenses of the respiratory tract (author's transl)].
In an attempt to define the composition of normal bronchial secretions, bronchial washings were obtained from normal areas of the lung in six patients. An analysis of proteins in the washings was carried out by crossed immunoelectrophoresis. The proteins detected were derived mainly from plasma and a very low content of secretory proteins was found. The composition of bronchial secretions and bronchial washings from a bronchitic patient was established and compared by crossed immunoelectrophoresis and gel filtration. The most important components were IgA, alpha1-antichymotrypsin and alpha1-antitrypsin, all of which are defense factors for the respiratory tract.
D001798:Blood Proteins / Q000032:analysis; D001980:Bronchi / Q000378:metabolism*; D001991:Bronchitis / Q000378:metabolism; D002850:Chromatography, Gel; D002908:Chronic Disease; D002918:Chymotrypsin / Q000037:antagonists & inhibitors; D005122:Exudates and Transudates; D006023:Glycoproteins / Q000032:analysis; D006801:Humans; D007106:Immune Sera; D007123:Immunoelectrophoresis, Two-Dimensional; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D011506:Proteins / Q000032:analysis*; D012141:Respiratory Tract Infections / Q000276:immunology*; D012709:Serum Albumin / Q000032:analysis; D013183:Sputum / Q000032:analysis*; D007507:Therapeutic Irrigation; D014168:Transferrin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis
D001798:Blood Proteins; D006023:Glycoproteins; D007106:Immune Sera; D007071:Immunoglobulin A, Secretory; D007074:Immunoglobulin G; D011506:Proteins; D012709:Serum Albumin; D014168:Transferrin; D000515:alpha 1-Antitrypsin; D002918:Chymotrypsin
Constituants protéiques de liquides de lavages bronchiques humains. Relations avec la défense de l'appareil respiratoire