Iodinated silicone-an antibacterial alloplastic material.
Iodine is readily miscible in silicones and will pass freely into and out of this material at highly predictable and constant rates. Iodinated silicone is thus an effective, controlled-rate delivery system for molecular iodine. This delivery system was shown to produce bacteriostatic and bactericidal effects in vitro, and at least bacteriostatic effects in vivo. Iodinated silicone produced a protective effect against the morbidity of infection in the mouse.
D000818:Animals; D001419:Bacteria / Q000187:drug effects*; D004058:Diffusion; D004926:Escherichia coli / Q000187:drug effects; D007455:Iodine / Q000494:pharmacology*; D007700:Kinetics; D051379:Mice; D008815:Mice, Inbred Strains; D008954:Models, Biological; D012828:Silicones / Q000494:pharmacology*; D013210:Staphylococcus / Q000187:drug effects
D012828:Silicones; D007455:Iodine