title: Pediatric appendicitis. A 20-year study of 1,640 children at Cook County (Illinois) Hospital.
abstract: Of 1,640 children with acute appendicitis treated at Cook County (Illinois) Hospital between Jan 1, 1957, and Dec 31, 1976, 35% had appendiceal perforation. Overall morbidity was 12.8% and mortality was 0.24%. Antibiotics, transperitoneal drainage, and delayed wound closure were used routinely in children with appendiceal perforation. Antibiotics and transperitoneal drains did not appreciably alter the incidence of intraabdominal abscess formation. Delayed wound closure in patients with appendiceal perforation reduced the incidence of wound infection by 75%.
mesh_terms: D000038:Abscess; D000208:Acute Disease; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001062:Appendectomy; D001064:Appendicitis / Q000188:drug therapy / Q000601:surgery* / Q000628:therapy*; D002429:Cecal Diseases / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D004322:Drainage; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007223:Infant; D007416:Intestinal Perforation / Q000628:therapy; D007813:Laparotomy; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal