[Biochemical methods for the detection of lead poisoning (author's transl)].
After a short description of sources of lead poisoning a review is given of toxicity, absorption, storage and excretion of lead. Afterwards its biochemical affects--especially the influence on the biosynthesis of heme--are treated. Methods for diagnosis of lead poisoning resulting from these affects--determination of coproporphyrine and delta-aminolevulinic acid excretion in urine, erythrocyte delta-aminolevulinic acid dehydratase activity and erythrocyte protoporphyrin--are discussed in detail.
D000622:Aminolevulinic Acid / Q000652:urine; D003306:Coproporphyrins / Q000652:urine; D004467:Economics; D004912:Erythrocytes / Q000201:enzymology / Q000378:metabolism; D006418:Heme / Q000096:biosynthesis; D006801:Humans; D007854:Lead / Q000009:adverse effects / Q000378:metabolism / Q000494:pharmacology; D007855:Lead Poisoning / Q000175:diagnosis* / Q000378:metabolism; D008722:Methods; D009784:Occupational Diseases / Q000139:chemically induced; D000623:Porphobilinogen Synthase / Q000097:blood; D011524:Protoporphyrins / Q000097:blood; D013405:Suicide
D003306:Coproporphyrins; D011524:Protoporphyrins; D007854:Lead; D006418:Heme; D000622:Aminolevulinic Acid; D000623:Porphobilinogen Synthase
Biochemische Methoden zum Nachweis der Bleivergiftung.