title: [Various methods of using lincomycin for treating acute and chronic hematogenic osteomyelitis in children].
abstract: Comparative data on the treatment of 209 children with acute and chronic hematogenic osteomyelitis are presented; 128 patients hospitalized before 1974 were treated with antibiotics, mainly penicillin and streptomycin without sensitivity testing. From 1974 81 children were treated with lincomycin; 80 per cent of the isolates were sensitive to this antibiotic. In lincomycin therapy the method of electrophoresis on the disease focus, intrabone administration of the drug and administration of the drug into the bone cavity together with the blood clot during surgical interventions in cases with chronic hematogenic osteomyelitis were used. A marked decrease in the rate of the chronic forms of the disease was registered (from 77.2 to 8.8 per cent).
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D001853:Bone Marrow; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular; D007478:Iontophoresis; D008034:Lincomycin / Q000008:administration & dosage*; D010019:Osteomyelitis / Q000188:drug therapy* / Q000209:etiology; D011300:Preoperative Care; D018805:Sepsis / Q000150:complications / Q000188:drug therapy*; D013630:Tampons, Surgical; D014945:Wound Healing / Q000187:drug effects
chemical_list: D008034:Lincomycin
vernacular_title: Razlichnye metody ispol'zovaniia linkomitsina dlia lecheniia ostrogo i khronicheskogo gematogennogo osteomielita u deteĭ.