[Analgetic and anti-inflammatory action of glaucine].
The authors examined the analgetic and antiinflammatory action of glaucine. They used the following methods for evaluation the analgetic action: chemical irritation, heating plate, heat-ray irritation, mechanical irritation of the normal and inflammatory tissues, electrical irritation and analgetic test. The following methods were used for evaluation of antiinflammatory action: effect on the edema of the rat paw and granulation phases of the inflammation in rats. Codeine and acetysal were used as control drugs. The results from the experiments showed that glaucine successfully inhibited the granulation phase of inflammation and did not affect edema of the rat paw, induce by yeast beer. The analgetic action of glaucine was weak and without practical significance.
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001060:Aporphines / Q000627:therapeutic use*; D003061:Codeine / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D004487:Edema / Q000188:drug therapy; D051379:Mice; D008815:Mice, Inbred Strains; D051381:Rats
D000894:Anti-Inflammatory Agents, Non-Steroidal; D001060:Aporphines; C005004:glaucine; D003061:Codeine
Prouchvaniia vurkhu analgetichnoto i protivovuzpalitelnoto deĭstvie na glautsina.