[Effect of vasopressin on the lower esophageal sphincter. Study on the action mechanism of vasopressin in bleeding esophageal varices].
The effect of vasopressin on the lower esophageal sphincter has been investigated in 12 healthy volunteers. Peripheral infusion of 0.2 U/min resulted in a significant (p less than 0.05) decrease in sphincter pressure. Accordingly, vasopressin-induced myogenic compression of bleeding varices has been ruled out as a potential additional hemostatic mechanism of vasopressin.
D004932:Esophageal and Gastric Varices / Q000150:complications; D004943:Esophagogastric Junction / Q000187:drug effects*; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy; D006490:Hemostatics; D006801:Humans; D008365:Manometry; D011312:Pressure; D014667:Vasopressins / Q000494:pharmacology*
D006490:Hemostatics; D014667:Vasopressins
Der Einfluss von Vasopressin auf den unteren ösophagealen Sphinkter. Eine Studie zum Wirkungsmechanismus von Vasopressin bei der Osophagusvarizenblutung.