[Characteristics of cytotoxic t-lymphocytes eluted from allogenic target cells].
Gain in the specific cytotoxic effect of immune lymphocytes after their absorption on the corresponding target cells (TC) and subsequent elution with pronase was caused not by the increase of the cytotoxic activity of individual cells, but by the quantitative enrichment of the population with the effector T-cells. Eluted and the initial immune lymphocytes failed to differ by the kinetics of absorption on the TC. The eluted lymphocyte fraction was characterized by a two fold increase in the T-cell content and a 4-5-fold increase in the number of DNA-synthesizing cells on account of an increase in the content of medium and large lymphocytes.
D000818:Animals; D000937:Antigen-Antibody Reactions; D003601:Cytotoxicity Tests, Immunologic; D004247:DNA / Q000096:biosynthesis; D007106:Immune Sera; D007158:Immunologic Techniques; D008214:Lymphocytes / Q000378:metabolism; D051379:Mice; D008815:Mice, Inbred Strains; D011402:Pronase; D013601:T-Lymphocytes / Q000276:immunology*
D007106:Immune Sera; D004247:DNA; D011402:Pronase
Kharakteristika tsitotoksicheskikh t-limfotsitov, éliuirovannykh s allogennykh kletok-misheneĭ