Novel R-plasmid-mediated beta-lactamase from Klebsiella aerogenes.
A novel beta-lactamase with a broad spectrum of activity against penicillins and cephalosporins has been detected in a strain of Klebsiella aerogenes. Its synthesis is mediated by an R-plasmid of molecular weight 64 x 10(6).
D000581:Amidohydrolases / Q000378:metabolism*; D002510:Cephalosporinase / Q000378:metabolism*; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000201:enzymology; D007709:Klebsiella / Q000201:enzymology*; D010405:Penicillinase / Q000378:metabolism*; D011815:R Factors
D000581:Amidohydrolases; D002510:Cephalosporinase; D010405:Penicillinase