Effects on plaque and gingivitis of a chlorhexidine dental gel in the mentally retarded.
The effectiveness of a 1% chlorhexidine-containing dental gel on dental plaque and gingival health was evaluated over a period of 6 months using a double-blind procedure. One hundred and seventeen mentally retarded subjects aged between 10-17 years resident in an institution were divided into two groups. One group was assigned daily brushing with the 1% chlorhexidine gel, the other group a placebo quinine sulfate-containing gel. No other form of oral hygiene was used during the experimental period. Assessment of dental plaque accumulation and gingivitis was made at 0, 1, 3, and 6 months. An assessment was also made 2 months after the gel was withdrawn from use and normal toothbrushing procedures resumed. No clinical or statistical advantage was noted in plaque or gingivitis scores in the group receiving chlorhexidine treatment during the 6-month period. This group showed a higher prevalence of tooth staining. It was concluded that periodontal severity and poor oral hygiene exceeded the plaque- and gingivitis-preventing potential of chlorhexidine.
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D001645:Biguanides / Q000627:therapeutic use*; D002648:Child; D002710:Chlorhexidine / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003773:Dental Plaque / Q000517:prevention & control*; D004341:Drug Evaluation; D005260:Female; D005782:Gels; D005891:Gingivitis / Q000517:prevention & control*; D006801:Humans; D008607:Intellectual Disability; D008297:Male; D014099:Toothbrushing
D001645:Biguanides; D005782:Gels; D002710:Chlorhexidine