title: Comparison of the proteolytic specificities of bovine and porcine pepsin A.
abstract: Bovine pepsin A inactivates pancreatic ribonuclease through a limited proteolysis the same way as does porcine pepsin A. The specific activity is lower and more dependent on the ionic strength. The proteolytic specificity of bovine pepsin A has been investigated with B-chain of oxidized porcine insulin as the substrate. The specificity resembles qualitatively that of porcine pepsin but with quantitative differences.
mesh_terms: D000818:Animals; D001665:Binding Sites; D002417:Cattle; D002852:Chromatography, Ion Exchange; D002854:Chromatography, Paper; D004590:Electrophoresis, Paper; D007328:Insulin; D010434:Pepsin A; D010455:Peptides / Q000032:analysis; D012260:Ribonucleases; D013045:Species Specificity; D013552:Swine
chemical_list: D007328:Insulin; D010455:Peptides; D012260:Ribonucleases; D010434:Pepsin A