title: Group B beta-hemolytic streptococcal colonization. Acquisition, persistence, and effect of umbilical cord treatment with triple dye.
abstract: Following an outbreak of group B beta-hemolytic streptococcal neonatal infection (GBS), a prevalence survey of GBS colonization was performed on 238 infants. No important differences were noted in the prevalence of colonization when the infants were grouped according to age. Follow-up of 24 colonized babies for three months disclosed that most had persistence of GBS at the rectum and pharynx. Local umbilical cord care with triple dye (TD) or hexachlorophene skin cleanser was compared with untreated controls with respect to rates of GBS colonization. At birth the colonization rates of the three groups were similar. The rate of acquisition of colonization with GBS was 1.0% in the TD group, 6.3% in the hexachlorophene group, and 8.3% in the control group. Triple dye was much more effective than no specific cord care or hexachlorophene in preventing acquisition of GBS colonization.
mesh_terms: D000166:Acridines / Q000627:therapeutic use*; D000367:Age Factors; D004396:Coloring Agents / Q000627:therapeutic use*; D004338:Drug Combinations; D005840:Gentian Violet / Q000627:therapeutic use*; D006582:Hexachlorophene / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control; D008396:Maryland; D010614:Pharynx / Q000382:microbiology; D011370:Proflavine / Q000627:therapeutic use*; D000644:Quaternary Ammonium Compounds / Q000627:therapeutic use*; D012007:Rectum / Q000382:microbiology; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control; D013292:Streptococcus agalactiae / Q000302:isolation & purification; D014470:Umbilical Cord / Q000382:microbiology
chemical_list: D000166:Acridines; D004396:Coloring Agents; D004338:Drug Combinations; D000644:Quaternary Ammonium Compounds; C014234:Triple Dye; D011370:Proflavine; D006582:Hexachlorophene; D005840:Gentian Violet