Irreversible inhibition of sodium entry sites in frog skin by a photosensitive amiloride analog.
A photosensitive binding reaction is described in which an analog of amiloride is bound to sites that control sodium entry into frog skin. This reaction results in irreversible inhibition of net sodium transport.
D000584:Amiloride / Q000031:analogs & derivatives / Q000494:pharmacology* / Q000528:radiation effects; D000818:Animals; D001001:Anura; D001692:Biological Transport / Q000187:drug effects; D003864:Depression, Chemical; D011719:Pyrazines / Q000494:pharmacology*; D011892:Rana catesbeiana; D012867:Skin / Q000187:drug effects* / Q000378:metabolism; D012964:Sodium / Q000378:metabolism*; D014466:Ultraviolet Rays
D011719:Pyrazines; D000584:Amiloride; D012964:Sodium