Neurosurgical infection treated with fosfomycin and 6-methylprednisolone.
A left parietal parasagittal meningioma was removed in a 67-year-old female patient. In the postoperative period she had a neurosurgical cerebral suppurating infection: subdural, epidural and epicranial, connected to the exterior by several fistulas. In the operative revision and after a culture, the germ causing the infection, E. coli, was isolated. Treatment was begun with 16 g of intravenous fosfomycin and 120 mg daily of 6-methylprednisolone intramuscularly, and this treatment cured the patient.
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000601:surgery*; D004359:Drug Therapy, Combination; D004927:Escherichia coli Infections / Q000188:drug therapy*; D005260:Female; D005578:Fosfomycin / Q000627:therapeutic use*; D006801:Humans; D008579:Meningioma / Q000601:surgery*; D008775:Methylprednisolone / Q000627:therapeutic use*; D013530:Surgical Wound Infection / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D005578:Fosfomycin; D008775:Methylprednisolone