Malakoplakia in a cadaver renal allograft: a case study.
Malakoplakia is an uncommon chronic inflammatory disease characterized by histocytes with intracellular Michaelis-Gutmann bodies. The etiology is uncertain, but it is thought that depressed macrophage phagocytosis of bacteria is important. This presentation describes a case of malakoplakia arising in a cadaver renal transplant. The association of long term immunosuppression and repeated E. coli urinary tract infections is discussed.
D002102:Cadaver; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D016030:Kidney Transplantation; D008287:Malacoplakia / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D011183:Postoperative Complications; D014184:Transplantation, Homologous