Influence of rec and pol genes on the maintenance of a Proteus plasmid (P-lac) in Escherichia coli.
The maintenance requirements of a Proteus plasmid, P-lac, in Escherichia coli have been investigated. P-lac could not be inherited by recB and polA1 mutants, and it requires a functional recC gene for maintenance. P-lac replication was inhibited by chloramphenicol.
D002701:Chloramphenicol / Q000494:pharmacology; D003227:Conjugation, Genetic; D004261:DNA Replication / Q000187:drug effects; D004269:DNA, Bacterial / Q000096:biosynthesis / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D005111:Extrachromosomal Inheritance; D005796:Genes; D007785:Lactose / Q000378:metabolism; D010957:Plasmids; D011513:Proteus mirabilis
D004269:DNA, Bacterial; D002701:Chloramphenicol; D007785:Lactose