[Lymphopenia and variations in T and B lymphocytes appearing immediately after irradiation (author's transl)].
Immunity tests were conducted in 21 patients with cancer, before and two months after irradiation. T and B lymphocyte counts were normal before irradiation when compared to a control group. Lymphopenia was present after irradiation affecting mainly the T lymphocytes (P = 0.005), whereas changes in B lymphocytes were not significant. These results suggest that irradiation has an immunosuppressive effect which should be studied in greater detail to establish possible therapeutic applications.
D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000166:cytology / Q000528:radiation effects*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008231:Lymphopenia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000532:radiotherapy; D011878:Radiotherapy / Q000009:adverse effects*; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000166:cytology / Q000528:radiation effects*
Lymphopénie et variation des lymphocytes T et B dans les suites immédiates de l'irradiation.