title: Circadian rhythmicity in the methylation of 5-hydroxyindoles and norepinephrine in the pineal gland of 10 day old rats.
abstract: In pineals of 10 day old rats 5-hydroxytryptophan, 5-hydroxyindole-3-acetic acid, N-acetylserotonin/5-hydroxytryptophol and norepinephrine are methylated following a circadian rhythm. During the night HIOMT and COMT activities were measured for the above mentioned substrates, while HIOMT activity for 5-hydroxytryptophan and N-acetylserotonin/5-hydroxytryptophol was also determined during daytime.
mesh_terms: D006916:5-Hydroxytryptophan / Q000378:metabolism*; D000121:Acetylserotonin O-Methyltransferase / Q000378:metabolism; D000818:Animals; D002394:Catechol O-Methyltransferase / Q000378:metabolism; D002940:Circadian Rhythm; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism*; D006917:Hydroxytryptophol / Q000378:metabolism*; D007211:Indoles / Q000378:metabolism*; D008745:Methylation; D009638:Norepinephrine / Q000378:metabolism*; D010870:Pineal Gland / Q000201:enzymology*; D051381:Rats; D012701:Serotonin / Q000378:metabolism
chemical_list: D007211:Indoles; D006917:Hydroxytryptophol; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D006916:5-Hydroxytryptophan; D000121:Acetylserotonin O-Methyltransferase; D002394:Catechol O-Methyltransferase; D009638:Norepinephrine