[Salmonella typhimurium--test system for detecting the mutagenic activity of environmental pollutants. II. Mutagenic effect of heavy metal salts in an in vitro system with metabolic activation].
Mutagenic effect of zinc chloride on Salmonella typhimurium strain was detected using in vitro metabolic activation system. Cadmium chloride showed no significant mutagenic activity in the same system. It is recommended to use both in vitro and in vivo metabolic activation systems in mutagenicity testing of chemicals.
D000818:Animals; D002104:Cadmium; D004785:Environmental Pollutants; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology; D009153:Mutagens; D012486:Salmonella typhimurium / Q000187:drug effects*; D015032:Zinc
D004785:Environmental Pollutants; D009153:Mutagens; D002104:Cadmium; D015032:Zinc
Salmonella typhimurium--test-sistema dlia vyiavleniia mutagennoĭ aktivnosti zagriazniteleĭ okruzhaiushcheĭ sredy. Soobshchenie II. Mutagennyĭ éffekt soleĭ tiazhelykh metallov v sisteme in vitro s metabolicheskoĭ aktivatsieĭ.