Establishment of a T-cell line from human lymphosarcoma.
A leukemic T-cell line, designated as TALL-1, has been established in continuous culture from the bone marrow of a patient with a leukemic phase of T-cell lymphosarcoma. TALL-1 cells have T-cell properties and lack Epstein-Barr virus or its genome. The cells of TALL-1 line are considered to have originated from the donor's leukemic cells on the basis of their cytogenetic, morphological, and surface features.
D000328:Adult; D002460:Cell Line; D006801:Humans; D007945:Leukemia, Lymphoid / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology*; D008297:Male; D013601:T-Lymphocytes / Q000473:pathology*