Mefenamic acid compared with ibuprofen in the treatment of rheumatoid arthritis.
A randomized double-blind within-patient study of mefenamic acid compared with ibuprofen was performed on forty patients with rheumatoid arthritis. It was concluded that mefenamic acid and ibuprofen had an analgesic and anti-inflammatory effect which was not significantly different in the dosages employed. Apart from six complaints of drowsiness of ibuprofen with two complaints on mefenamic acid, the side-effects were similar.
D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use*; D008297:Male; D008528:Mefenamic Acid / Q000627:therapeutic use*; D008875:Middle Aged; D010666:Phenylpropionates / Q000627:therapeutic use*
D010666:Phenylpropionates; D008528:Mefenamic Acid; D007052:Ibuprofen