Semiautomated turbidimetric bioassay for the ionophore A23187.
The inhibitory effect of A23187 against Staphylococcus aureus was used to quantitate the activity of this ionophore in fermentation samples and in isolation and crystallization samples. The assay was shown to be rapid and reproducible.
D000900:Anti-Bacterial Agents / Q000032:analysis*; D001322:Autoanalysis; D001681:Biological Assay; D000001:Calcimycin / Q000032:analysis* / Q000494:pharmacology; D008722:Methods; D009391:Nephelometry and Turbidimetry; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000001:Calcimycin