[Role of the sympathetic-adrenal and kallikrein-kinin systems in regulating central hemodynamics in acute experimental occlusion of the terminal portion of the aorta].
The role of the sympatheticoadrenal and kallikrein-kinin systems in the pathogenesis of hemodynamic disorders was studied in 29 dogs with acute experimental occlusion of the terminal part of the aorta. Data confirming the close dependence of the indices of central hemodynamics on the activity of the sympatheticoadrenal and kallikrein-kinin systems are presented. Close positive correlative connection between activation of the sympatheticoadrenal and kallikrein-kinin systems was revealed. The possible mechanisms of the correction of hemodynamic disorders in severe degree of ischemia by means of agents blocking the kallikrein system are discussed.
D000311:Adrenal Glands / Q000503:physiopathology*; D000818:Animals; D001012:Aorta, Abdominal / Q000503:physiopathology; D001018:Aortic Diseases / Q000188:drug therapy / Q000503:physiopathology*; D007611:Aprotinin / Q000627:therapeutic use; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D004617:Embolism / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics; D007610:Kallikreins / Q000097:blood*; D007705:Kinins / Q000097:blood*; D008297:Male; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D013997:Time Factors
D007705:Kinins; D007611:Aprotinin; D007610:Kallikreins
Rol' simpatiko-adrenalovoĭ i kallikrein-kininovoĭ sistem v reguliatsii tsentral'no gemodinamiki pri ostroĭ éksperimental'noĭ okkliuzii terminal'nogo otdela aorty.