Vision threshold profiles in X-linked retinitis pigmentosa.
Absolute thresholds for blue-green and red stimuli were measured along the horizontal and vertical meridans in two patients with X-linked retinitis pigmentosa. From these data, we deduced that cones mediate detection of both stimuli in the central 10 degrees, there is a ring scotoma in the mid-periphery, and in the far periphery rods mediate detection of both stimuli. Conclusions drawn from the psychophysical measures about rod and cone function across the retina are in point-by-point agreement with the data of a recent electron microscopic study by Szamier et al. on the retina of a 24-year-old X-linked retinitis pigmentosa patient.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003118:Color Perception / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D009755:Night Blindness / Q000150:complications; D010786:Photoreceptor Cells / Q000502:physiology*; D012160:Retina / Q000473:pathology / Q000648:ultrastructure; D012174:Retinitis Pigmentosa / Q000150:complications / Q000235:genetics* / Q000503:physiopathology; D012607:Scotoma / Q000150:complications; D012684:Sensory Thresholds; D014792:Visual Acuity; D014794:Visual Fields; D014960:X Chromosome