Hypofibrinogenemia-dysfibrinogenemia and von Willebrand's disease in the same family.
Two Puerto Rican families were studied. One family included a number of members with dysfibrinogenemia occasionally associated with hypofibrinogenemia. The second family had members with von Willebrand's disease. The two diseases merged in the proband's immediate family; the affected members of this family exhibited a mild bleeding disorder. Others in the two families had no obvious bleeding tendency.
D000328:Adult; D000347:Afibrinogenemia / Q000097:blood / Q000150:complications / Q000235:genetics*; D001778:Blood Coagulation Disorders / Q000097:blood / Q000150:complications / Q000235:genetics*; D001780:Blood Coagulation Tests; D002648:Child; D002675:Child, Preschool; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D008297:Male; D010375:Pedigree; D011647:Puerto Rico; D014842:von Willebrand Diseases / Q000097:blood / Q000150:complications / Q000235:genetics*
D005340:Fibrinogen