[Analysis of the macrophage function in sarcoidosis].
This study demonstrates that, in spite of the fairly normal functional capacity of T lymphocytes in sarcoidosis, a deficit of cell-mediated immunity frequently develops. It is shown that monocytes of sarcoidosis seem to share in responsibility for the appearance of this deficit. Soluble factors from sensitized healthy monocytes are shown to be capable of restoring this capacity.
D002452:Cell Count; D006801:Humans; D007111:Immunity, Cellular; D008263:Macrophage Migration-Inhibitory Factors / Q000096:biosynthesis; D008264:Macrophages / Q000276:immunology*; D012507:Sarcoidosis / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D008263:Macrophage Migration-Inhibitory Factors
Analyse de la fonction des macrophages dans la sarcoïdose.