title: A review of drug "clearance times" in racehorses.
abstract: A review is presented of published and some unpublished work dealing with aspects of drug clearance from horses. This work includes plasma half-lives and urinary clearance times for specified drugs, as well as a consideration of more general factors likely to influence these values. The review is presented primarily as a guide to the veterinary surgeon in practice, to assist in the drug therapy of horses without contravening the Rules of Racing relating to doping.
mesh_terms: D000075:Acepromazine / Q000378:metabolism; D000661:Amphetamine / Q000378:metabolism; D000818:Animals; D002110:Caffeine / Q000378:metabolism; D004809:Ephedrine / Q000378:metabolism; D004837:Epinephrine / Q000378:metabolism; D005938:Glucocorticoids / Q000378:metabolism; D006736:Horses / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism; D010113:Oxyphenbutazone / Q000378:metabolism; D010424:Pentobarbital / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010653:Phenylbutazone / Q000378:metabolism
chemical_list: D005938:Glucocorticoids; D004364:Pharmaceutical Preparations; D002110:Caffeine; D000075:Acepromazine; D000661:Amphetamine; D010653:Phenylbutazone; D004809:Ephedrine; D010113:Oxyphenbutazone; D010424:Pentobarbital; D009638:Norepinephrine; D004837:Epinephrine