Inward rectification in skeletal muscle: a blocking particle model.
Inwardly rectifying potassium currents were measured in resting frog skeletal muscle in different [K]o. A modle is presneted for inward rectification which supposes that the potassium conductance depends on the K+ concentration within a channel and is reduced by a blocking particle which is driven into the channel by depolarization.
D000818:Animals; D001001:Anura; D001665:Binding Sites; D001667:Binding, Competitive; D002414:Cations, Monovalent / Q000378:metabolism; D004553:Electric Conductivity; D066298:In Vitro Techniques; D007473:Ion Channels; D008954:Models, Biological; D009132:Muscles / Q000378:metabolism* / Q000502:physiology; D009994:Osmolar Concentration; D010539:Permeability; D011188:Potassium / Q000378:metabolism*; D011896:Rana temporaria
D002414:Cations, Monovalent; D007473:Ion Channels; D011188:Potassium