T and B lymphocytes in the liver and peripheral blood of subjects with acute and chronic hepatitis.
E and EAC rosette-forming cells in the peripheral blood and in the liver of subjects with acute and chronic hepatitis were studied. We found a highly significant reduction (P less than 0.01) of E rosette percentage in the lymphocytes isolated from the liver patients with chronic persistent, and chronic active, hepatitis. EAC rosette-forming cells were significantly increased in the liver of patients with chronic active hepatis (P less than 0.01). In this condition lymphocytes with Fc receptor were also found.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology*; D002908:Chronic Disease; D005260:Female; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006525:Hepatitis, Viral, Human / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008099:Liver / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
D006514:Hepatitis B Surface Antigens; D007136:Immunoglobulins