Major transplantation antigens in host responses to infection.
There is increasing support for the concept that in all of their varied immunologic functions, T lymphocytes act through a dual specificity. In the case of intracellular viral infections, the recognition required for cytolysis involves both a "self" component, coded for by the genes that specify the major transplantation antigens, and an "X" component, provided by viral antigens expressed on the target-cell surface.
D000818:Animals; D001424:Bacterial Infections / Q000276:immunology; D006183:H-2 Antigens / Q000032:analysis; D006680:HLA Antigens / Q000032:analysis; D006649:Histocompatibility Antigens / Q000032:analysis*; D006801:Humans; D007239:Infections / Q000276:immunology*; D007694:Killer Cells, Natural / Q000276:immunology; D008216:Lymphocytic Choriomeningitis / Q000276:immunology; D051379:Mice; D013601:T-Lymphocytes / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology; D014777:Virus Diseases / Q000276:immunology
D006183:H-2 Antigens; D006680:HLA Antigens; D006649:Histocompatibility Antigens