Chasing Crohn's.
The importance of Crohn's disease in oral pathology is briefly discussed. A series of experiments using immunofluorescent tracing techniques is described which culminates in the identification of a Crohn's-specific circulating antibody which reacts with autologous oral mucosa in vitro. It is suggested that this forms the basis of a diagnostic test.
D000328:Adult; D000888:Antibodies, Anti-Idiotypic / Q000032:analysis; D000974:Antibodies, Antinuclear / Q000032:analysis; D001327:Autoimmune Diseases; D003424:Crohn Disease / Q000276:immunology* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000276:immunology* / Q000473:pathology; D009061:Mouth Mucosa / Q000276:immunology
D000888:Antibodies, Anti-Idiotypic; D000974:Antibodies, Antinuclear