[Results of an experimental study of the antitumor activity of 1-asparaginase from E. coli and Erw. carotovora].
The antitumour activity of the preparations of L-asparaginase from E. coli and Erw. carotovora with respect to lymphadenosis L-5178 and Yorker's carcinosarcoma (ascitic cariants) has been established. No difference in antitumour efficacy of the preparation of L-asparaginase obtained from E. coli and Erw. carotovora was noted.
D000818:Animals; D001215:Asparaginase / Q000008:administration & dosage / Q000494:pharmacology*; D002279:Carcinoma 256, Walker / Q000188:drug therapy; D002478:Cells, Cultured; D002645:Chickens; D004353:Drug Evaluation, Preclinical; D004885:Erwinia / Q000201:enzymology*; D004926:Escherichia coli / Q000201:enzymology*; D066298:In Vitro Techniques; D007942:Leukemia, Experimental / Q000188:drug therapy; D008223:Lymphoma / Q000188:drug therapy; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy
D001215:Asparaginase
Rezul'taty éksperimental'nogo izucheniia protivoopukholevoĭ aktivnosti 1-asparaginazy iz E. coli i Erw. carotovora