High mutageniticity of metabolically activated chrysene 1,2 dihydrodiol: evidence for bay region activation of chrysene.
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002911:Chrysenes / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004852:Epoxy Compounds / Q000494:pharmacology; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism*; D009153:Mutagens; D010105:Oxygenases / Q000378:metabolism; D010616:Phenanthrenes / Q000494:pharmacology*; D051381:Rats; D012486:Salmonella typhimurium / Q000235:genetics*; D013329:Structure-Activity Relationship
D002911:Chrysenes; D004852:Epoxy Compounds; D009153:Mutagens; D010616:Phenanthrenes; D003577:Cytochrome P-450 Enzyme System; D010105:Oxygenases