[Stimulating action of the albumin fraction of soluble placental proteins on T- and B-lymphocyte transformation].
Under study was the effect of the albumin fraction of soluble placental proteins on the transformation of T- and B-lymphocytes, stimulated by Salmonellae phytohemagglutinin and lipopolysaccharides, respectively. Placental proteins were separated by their fractional sedimentation with ammonium sulphate and subsequent gelfiltration on Sephadex-G-200. The albumin fraction of placental proteins was shown to stimulated the reaction of the T- and B-lymphocytes blasttransformation. Some possible mechanisms of this effect are discussed.
D000418:Albumins / Q000302:isolation & purification / Q000494:pharmacology*; D001402:B-Lymphocytes / Q000187:drug effects*; D002478:Cells, Cultured; D005260:Female; D006801:Humans; D037102:Lectins / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000494:pharmacology; D008213:Lymphocyte Activation / Q000187:drug effects*; D010920:Placenta; D011247:Pregnancy; D012475:Salmonella; D012995:Solubility; D013268:Stimulation, Chemical; D013601:T-Lymphocytes / Q000187:drug effects*
D000418:Albumins; D037102:Lectins; D008070:Lipopolysaccharides
Stimuliruiushchee deĭstvie al'buminovoĭ fraktsii rastvorimykh belkov platsenty na transformatsiiu T- i B-limfotsitov.