title: Stability of patulin to sulfur dioxide and to yeast fermentation.
abstract: The affinity of patulin for sulfur dioxide (SO2) is much less than was previously reported and is of little significance at the SO2 concentrations (below 200 ppm) used in the processing of apple juice and cider. However, at concentrations of 2000 ppm SO2 and 15 ppm patulin, combination was 90% complete in 2 days. Removal of SO2 liberated only part of the patulin, which suggests that 2 mechanisms are involved: one reversible (opening the hemiacetal ring) and one irreversible (SO2 addition at the double bond). Test with 2 yeasts used in English commercial cider making confirmed that patulin is effectively removed during yeast fermentation.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D004355:Drug Stability; D005285:Fermentation; D010365:Patulin / Q000032:analysis / Q000037:antagonists & inhibitors; D011714:Pyrans / Q000032:analysis / Q000037:antagonists & inhibitors; D012441:Saccharomyces cerevisiae / Q000254:growth & development*; D013458:Sulfur Dioxide / Q000494:pharmacology*
chemical_list: D011714:Pyrans; D013458:Sulfur Dioxide; D010365:Patulin