Prolonged curarisation following renal transplantation. A retrospective study.
A retrospective study of postoperative respiratory morbidity in 247 patients requiring renal transplantation between 1955 and 1973 showed that 7 patients required postoperative controlled ventilation for up to 6 days. The nondepolarising relaxants tubocurarine and pancuronium were used in only 65 patients, but all 7 cases of respiratory failure occurred in this group. This suggests that the use of these drugsin anephric patients is potentially hazardous so far as postoperative respiratory insufficiency is concerned.
D000293:Adolescent; D000328:Adult; D002648:Child; D006801:Humans; D007223:Infant; D016030:Kidney Transplantation; D008875:Middle Aged; D010197:Pancuronium / Q000009:adverse effects* / Q000494:pharmacology; D011183:Postoperative Complications; D012131:Respiratory Insufficiency / Q000139:chemically induced*; D012189:Retrospective Studies; D013390:Succinylcholine / Q000009:adverse effects; D014184:Transplantation, Homologous; D014403:Tubocurarine / Q000009:adverse effects*
D013390:Succinylcholine; D010197:Pancuronium; D014403:Tubocurarine