An animal model for childhood convoluted T-cell lymphoma.
The light microscopic and ultrastructural characteristics of the AKR-J mouse lymphoma are described in detail. Clinical and histologic facets of convoluted T-cell lymphoma of childhood and AKR-J mouse lymphoma are reviewed. The remarkably close correlation between these two entities is demonstrated. The possibility that this mouse tumor should be utilized as a model for convoluted T-cell lymphoma of childhood is emphasized.
D000818:Animals; D004195:Disease Models, Animal; D008198:Lymph Nodes / Q000473:pathology / Q000648:ultrastructure; D008223:Lymphoma / Q000473:pathology; D051379:Mice; D008806:Mice, Inbred AKR; D008855:Microscopy, Electron, Scanning; D013601:T-Lymphocytes / Q000648:ultrastructure