The antihypertensive effect of pindolol (Visken) alone and combined with clopamide (Brinaldix).
After a two week washout period 25 patients with moderate to severe essential hypertension were treated with pindolol. In 12 patients the reduction in blood pressure was excellent and treatment with pindolol was continued. In 13 patients treatment was supplemented subsequently with clopamide and 12 patients had a satisfactory result. Side-effects were few and mild.
D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D003005:Clopamide / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010869:Pindolol / Q000008:administration & dosage / Q000627:therapeutic use*; D011674:Pulse / Q000187:drug effects
D003005:Clopamide; D010869:Pindolol