title: [Oral manifestations of Letterer-Siwe disease. Clinical and histological study of lesions centered in the mouth of a infant with acute and disseminated histiocytosis X].
abstract: The clinical, radiological and histological aspects of acute histiocytosis X of Letterer-Siwe disease are reviewed after personal observation of such cases. In spite of many advanced hypotheses the etiopathogenesis of Histiocytosis X is wide open to research. The diagnosis became possible by the discovery of histiocyte cells of a special order, the X-bodies, under the E. M. Recent research allows a classification of Letterer-Siwe disease, Hand-Schüller-Christian disease, and the eosinophilic granuloma under the same nosologic grouping. Finally, the prognosis of the Letterer-Siwe disease-so far much in the dark-may be improved by a properly conducted therapy.
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D004804:Eosinophils / Q000473:pathology; D006646:Histiocytosis, Langerhans-Cell / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D009059:Mouth Diseases / Q000473:pathology*; D009061:Mouth Mucosa / Q000473:pathology; D011859:Radiography
vernacular_title: Manifestations buccales de la maladie de Letterer-Siwe. Etude clinique et histologique des lésions siégeant dans la bouche chez un nourisson atteint d'Histiocytose aiguë et disséminée.