[Quantitative interrelationships between the T- and B-cell populations of mouse lymphoid organs].
The number of thymocytes and splenic T-lymphocytes correlate negatively. After the treatment of mice with cortisol, this negative correlation changes for a positive one. It is proposed that the negative correlation between cortisone-sensitive thymocytes and splenic T cells is mediated by cortisone-resistant thymocytes. The negative correlations were also found between amounts of T-cells in mesenteric lymph nodes and in Peyer's patches, the positive correlations being seen between numbers of splenic and lymph nodes T-lymphocytes. No correlations between B-cell populations in different organs were revealed. Apparently, correlations between lymphocyte populations reflect some aspect of hierachic structure of the lymphoid system.
D000818:Animals; D001402:B-Lymphocytes; D002452:Cell Count; D003348:Cortisone / Q000494:pharmacology; D008198:Lymph Nodes / Q000166:cytology; D008221:Lymphoid Tissue / Q000166:cytology*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009928:Organ Specificity; D010581:Peyer's Patches / Q000166:cytology; D013154:Spleen / Q000166:cytology; D013601:T-Lymphocytes / Q000187:drug effects; D013950:Thymus Gland / Q000166:cytology
D003348:Cortisone
Kolichestvennye vzaimootnosheniia populiatsiĭ T- i B-kletok limfoidnykh organov mysheĭ.