Imbalances in T cell subpopulations in multiple sclerosis patients.
Abnormal proportions of a distinct T cell subpopulation able to bind IgG immune complexes (T.G cells) were found in peripheral blood samples from patients with MS. About 50% of the patients examined had an overabundance of T.G cells. The possible role of these cells in the pathogenesis of MS is considered.
D001772:Blood Cell Count; D002469:Cell Separation; D006801:Humans; D009103:Multiple Sclerosis / Q000209:etiology / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*