Quantification of vestibular compensation in unilateral Meniere's disease.
The main parameters of the vestibulo-ocular reflex (i.e. the gain or reflectivity, the long-time constant of the semicircular canals, the time constant of the mechano-neural transduction, and that of the central leaky integrator) were computed from the post-rotational nystagmic responses of unilateral Meniere's patients. Comparison with normal subjects showed a decrease of the first two parameters both in CW and CCW responses. No significant changes were observed in the remaining parameters. Probably due to a process of central compensation, a high level of symmetry was observed mainly in longstanding patients.
D000328:Adult; D000368:Aged; D002150:Caloric Tests; D004584:Electronystagmography; D005133:Eye Movements; D006801:Humans; D008575:Meniere Disease / Q000175:diagnosis* / Q000503:physiopathology; D008875:Middle Aged; D012399:Rotation; D014722:Vestibule, Labyrinth / Q000503:physiopathology*