[Circulating immune complexes and anti-IgG antibodies in rheumatoid arthritis].
Anti-IgG antibodies were studied in 222 patients hospitalized in a Rheumatology service using "radio-immuno-precipitation-PEG-assay" (RIPEGA), The presence of anti-IgG antibodies was observed in 94 per cent of sero-positive rheumatoid arthritis (RA+), 88 percent of seronegative rheumatoid arthritis (RA--), 50 percent miscellaneous chronic inflammatory rheumatisms (CIR) and 77 percent of no-classifiable chronic inflammatory rheumatisms. The study of circulating immune complexes (CIC) using the CIC-125 I linkage tests, carried out on 101 RA cases, demonstrated their presence in 80 per cent of RA+ and 85 per cent of RA--. The comparison of these two factors during RA showed a concordant relationship that was statistically significant. The presence of the rheumatoid factor (RF) in the form of complexes in the blood stream, is discussed.
D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D000936:Antigen-Antibody Complex; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D003172:Complement C1; D006801:Humans; D007074:Immunoglobulin G; D007457:Iodine Radioisotopes; D011233:Precipitin Tests; D011863:Radioimmunoassay / Q000379:methods; D012217:Rheumatoid Factor / Q000032:analysis
D000888:Antibodies, Anti-Idiotypic; D000936:Antigen-Antibody Complex; D003172:Complement C1; D007074:Immunoglobulin G; D007457:Iodine Radioisotopes; D012217:Rheumatoid Factor
Complexes immuns circulants et anticorps anti-IgG dans la polyarthrite rhumatoïde.