title: Synaptic membrane protein D2 in the cerebrospinal fluid of manic-melancholic patients.
abstract: The synaptic membrane protein D2 was measured in the cerebrospinal fluid (CSF) of manic-melancholic patients. The concentration of D2 increased with the age of the patients until about 35 years of age. No difference was found between the D2-concentration in CSF from a control group compared with different manic-melancholic subgroups. The D2-concentration in CSF collected from the patients during depression or mania was compared with CSF collected from the same patients when their moods were normalized. In the case of the depressed patients, we found that the D2-concentration increased slightly when the mood was normalized.
mesh_terms: D000328:Adult; D000367:Age Factors; D001714:Bipolar Disorder / Q000134:cerebrospinal fluid*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000134:cerebrospinal fluid*; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000134:cerebrospinal fluid*; D013048:Specimen Handling; D013570:Synaptic Membranes / Q000032:analysis
chemical_list: D008565:Membrane Proteins; D009419:Nerve Tissue Proteins