title: Antithyroglobulin (ATG) production by peripheral blood leukocytes in vitro.
abstract: Antithyroglobulin is produced in vitro by pokeweed mitogen stimulation of peripheral blood lymphocytes from patients whose serum contains the autoantibody. Antithyroglobulin synthesis requires T lymphocyte help but is suppressed by larger numbers of T lymphocytes. T cells from both patients and normals perform both of these functions.
mesh_terms: D000917:Antibody Formation; D006801:Humans; D007518:Isoantibodies / Q000096:biosynthesis*; D008934:Mitogens; D011863:Radioimmunoassay; D013601:T-Lymphocytes / Q000276:immunology*; D013954:Thyroglobulin / Q000276:immunology*
chemical_list: D007518:Isoantibodies; D008934:Mitogens; D013954:Thyroglobulin