title: Orbital apex syndrome secondary to herpes zoster ophthalmicus.
abstract: Two women, one with Hodgkin's disease and the other with no malignancy, developed herpes zoster with optic neuropathy and total ophthalmoplegia. Both patients developed an associated mild meningoencephalitis with a predominantly lymphocytic spinal fluid reaction that cleared spontaneously. The patient with Hodgkin's disease suffered a protracted course of the disease and developed a secondary bacterial endophthalmitis that necessitated an envisceration of the left eye. The patient without evidence of immunologic deficit recovered quickly with administration of corticosteroids.
mesh_terms: D000368:Aged; D005260:Female; D006563:Herpes Zoster Ophthalmicus / Q000150:complications* / Q000175:diagnosis; D006689:Hodgkin Disease / Q000150:complications; D006801:Humans; D008590:Meningoencephalitis / Q000209:etiology; D008875:Middle Aged; D009882:Ophthalmic Nerve; D009886:Ophthalmoplegia / Q000175:diagnosis / Q000209:etiology*; D009902:Optic Neuritis / Q000150:complications* / Q000175:diagnosis; D009915:Orbit; D013577:Syndrome