One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
One hundred and twenty-seven cultured human tumor cell lines produced tumors after sc inoculation of 1-20 million cells into nude mice. They included 56 carcinoma lines, 14 sarcoma lines, and 57 lines from miscellaneous tumors and were all glucose-6-phosphate dehydrogenase type B. Twenty-nine percent of the lines produced tumors of 1 cm3 size within 1 month and 41% in the second month after inoculation. The histopathology correlated with the human tumor of origin in all cases.
D000818:Animals; D002460:Cell Line; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis; D006367:HeLa Cells / Q000201:enzymology; D006801:Humans; D007527:Isoenzymes / Q000032:analysis; D008297:Male; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000201:enzymology / Q000473:pathology*; D014183:Transplantation, Heterologous
D007527:Isoenzymes; D005954:Glucosephosphate Dehydrogenase