[Evaluation of thymic hormone and E-rosettes in patients with IgA deficiency].
We have investigated lymphocyte subpopulations and T cell functions, in particular E rosettes and serum level of thymic factor in ten young patients (aged 6 to 20) with partial and selective IgA deficiency. The control group included ten age-matched healthy subjects. Significantly depressed levels of serum thymic factor were found in six patients. These results were correlated with the decreased number of E rosettes found in five of them, and support a T-cell involvement in IgA deficiency.
D000293:Adolescent; D000328:Adult; D002648:Child; D004406:Dysgammaglobulinemia / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A; D007153:Immunologic Deficiency Syndromes / Q000276:immunology*; D007158:Immunologic Techniques; D013601:T-Lymphocytes / Q000276:immunology*; D013951:Thymus Hormones / Q000032:analysis*
D007070:Immunoglobulin A; D013951:Thymus Hormones
Evaluation de l'hormone thymique et des rosettes T au cours des déficits en IgA