title: [Resistance to phage MS2 induced in E. coli by infection with that phage].
abstract: A sensitive cell of E. coli AB 259 Hfr 3000 infected with RNA-containing phage MS2 produces phages and simultaneously continues to divide showing a segregation of sensitive cells which maintain new cycles of the infection. Phage multiplication in the sensitive cell induces phage-resistant forms in the progeny of this cell. The described phenomenon is not caused by selection of pre-existing F--cells, but may result from a direct interaction of phage products with the episomal DNA coding proteins for F-pili. The elucidation of the mechanisms of this phenomenon may pave the way to studies of the DNA- and RNA- containing genome interaction within the cell, the mechanisms of persistent infection and the causes of different degrees in phage virulence.
mesh_terms: D003090:Coliphages; D004926:Escherichia coli; D005144:F Factor; D012367:RNA, Viral
chemical_list: D012367:RNA, Viral
vernacular_title: Ustoĭchivost' k fagu MS2, indutsirovannaia u E. coli pri zarazhenii étim fagom.