Histiocytic lymphoma in the brain as the only manifestation of relapse following remission maintainance with BCG immunotherapy.
This report describes an unusual case of lymphoma which, after 54 months of complete remission induced with chemotherapy and maintained with BCG immunotherapy, relapsed in the brain alone. It is possible that the immunotherapy led to this pattern of relapse: this is supported by several other studies. The difficulty in diagnosing brain lymphoma is emphasized.
D001500:BCG Vaccine / Q000009:adverse effects / Q000627:therapeutic use; D001921:Brain / Q000276:immunology; D001932:Brain Neoplasms / Q000209:etiology / Q000473:pathology; D001943:Breast Neoplasms / Q000628:therapy; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000473:pathology / Q000628:therapy; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012008:Recurrence; D012075:Remission, Spontaneous; D013967:Thyroiditis, Autoimmune / Q000150:complications; D013997:Time Factors
D001500:BCG Vaccine