Homozygous alpha1 antitrypsin deficiency with unusual associations:  a case report.
The rare association of protease inhibitor deficiency (Pi(zz) genotype) in a black American with chronic, obstructive pulmonary disease due to asthmatic bronchitis, rather than basal pan lobular emphysema, is presented. The late onset of symptoms, despite environmental exposures, is also unusual in this homozygote, as is his ethnic background.
D001741:Black or African American; D001991:Bronchitis / Q000150:complications* / Q000175:diagnosis; D006720:Homozygote; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D014481:United States; D019896:alpha 1-Antitrypsin Deficiency