Characterisation of immunofluorescent heterophile antibodies which may be confused with autoantibodies.
Approximately 6% of sera submitted for routine immunofluorescent autoantibody screeening produced characteristic reaction patterns against a variety of animal and human tissues. It is suggested that these non-tissue-specific patterns represent a complex family of heterophile antibodies which could be confused with certain autoantibodies. It is further suggested that these heterophile antibodies bear a relationship to IgG isohaemagglutinins.
D000818:Animals; D000910:Antibodies, Heterophile / Q000032:analysis*; D000918:Antibody Specificity; D001323:Autoantibodies / Q000032:analysis*; D005188:False Negative Reactions; D005189:False Positive Reactions; D005455:Fluorescent Antibody Technique; D006168:Guinea Pigs; D006801:Humans; D051379:Mice; D051381:Rats
D000910:Antibodies, Heterophile; D001323:Autoantibodies