[Increase in stability of isolated tissues and proteins caused by the action of chemical stimulants].
Chemical agents in subtoxic concentrations prolongate the survival time of living muscles and the time of contractile ability of glycerinated muscles. They preserve also the native property of actomyosine over the control time. The increase of resistance of living muscles and their models may be explained by stabilization of proteins or of their complexes. It is accompanied by the change of the indices of the functional state of the living muscle--by the decrease of the binding of vital dyes, by the hyperpolarization, by reducing the consumption of O2 and by the conservation of the quantity of SH groups at the high level.
D000205:Actomyosin; D000818:Animals; D001001:Anura; D002697:Chloral Hydrate / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000494:pharmacology*; D066298:In Vitro Techniques; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects; D008931:Mitochondria, Muscle / Q000187:drug effects; D009119:Muscle Contraction / Q000187:drug effects; D009124:Muscle Proteins; D009132:Muscles / Q000187:drug effects* / Q000502:physiology; D010085:Oxidative Phosphorylation / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects; D011489:Protein Denaturation / Q000187:drug effects; D012965:Sodium Chloride / Q000494:pharmacology; D013094:Spermatozoa / Q000187:drug effects / Q000378:metabolism; D013438:Sulfhydryl Compounds / Q000378:metabolism; D013552:Swine; D014508:Urea / Q000494:pharmacology; D014520:Urethane / Q000494:pharmacology*
D009124:Muscle Proteins; D013438:Sulfhydryl Compounds; D014520:Urethane; D000431:Ethanol; D002697:Chloral Hydrate; D012965:Sodium Chloride; D014508:Urea; D000205:Actomyosin
Uvelichenie ustoĭchivosti izolirovannykh tkaneĭ i belkov, vyzvannoe deĭstviem khimicheskikh razdrazhiteleĭ.