Relapsing E. coli K1 antigen meningitis in a newborn.
A male infant of 32 weeks' gestational age who presented with recurrent apnoea on the second day of life was shown to have an Escherichia coli K1 antigen meningitis. Relapse occurred 6 days after an adequate systemic course of gentamicin and chloramphenicol and intrathecal gentamicin. This was successfully treated with intraventricular gentamicin and systemic cotrimoxazole. The need to maintain a high index of suspicion for meningitis in the newborn period and to treat adequately the frequently accompanying ventriculitis is emphasized.
D000942:Antigens, Bacterial / Q000032:analysis; D004926:Escherichia coli / Q000276:immunology; D004927:Escherichia coli Infections / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008581:Meningitis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D011135:Polysaccharides, Bacterial
D000942:Antigens, Bacterial; D011135:Polysaccharides, Bacterial