[Evaluation of the therapeutic and toxic action of platinum cis-dichlorodiamine].
The substance under study was employed in 9 patients with a far-advanced lesion. Dosage of 7.5 mg/m2 of the body surface failed to render any effect, whereas 15 mg/m2 induced partial regression in 2 patients and stabilization of the process in another 2 patients. Some toxic phenomena were noted on the part of the digestive tract.
D000230:Adenocarcinoma / Q000188:drug therapy; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy; D001984:Bronchial Neoplasms / Q000188:drug therapy; D002945:Cisplatin / Q000009:adverse effects / Q000627:therapeutic use* / Q000633:toxicity; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D006689:Hodgkin Disease / Q000188:drug therapy; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012075:Remission, Spontaneous; D013274:Stomach Neoplasms / Q000188:drug therapy; D013997:Time Factors
D002945:Cisplatin
Otsenka terapevticheskogo i toksicheskogo deĭstviia tsis-dikhlordiamina platiny.