Immune reactions associated with practolol therapy.
A review of adverse reactions following practolol therapy is presented. The appearance of antinuclear antibodies seems to herald the clinical manifestations. Antinuclear antibodies were found in 30% of patients treated with practolol for prolonged periods. It is suggested that patients who develop an immune reaction following practolol metabolize the drug differently than those who do not.
D000974:Antibodies, Antinuclear; D000917:Antibody Formation / Q000187:drug effects; D004342:Drug Hypersensitivity / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D011217:Practolol / Q000009:adverse effects*
D000974:Antibodies, Antinuclear; D011217:Practolol