[Is the sodium ionic channel a cyclic hexapeptide? (author's transl)].
A cyclic hexapeptide affords a model of an ionic channel, permeable to Na+ but not to K+. The selective fixation of tetrodotoxin and saxitoxin could occur through six hydrogen bonds, one with each of carbonyles of the crown exposed at the outside of the membrane.
D001665:Binding Sites; D007473:Ion Channels; D008958:Models, Molecular; D010456:Peptides, Cyclic; D012530:Saxitoxin; D012964:Sodium / Q000378:metabolism*; D013779:Tetrodotoxin
D007473:Ion Channels; D010456:Peptides, Cyclic; D012530:Saxitoxin; D013779:Tetrodotoxin; D012964:Sodium
Le pore ionique perméable au sodium est-il un hexapeptide cyclique?