Tris(2,3-dibromopropyl) phosphate: mutagenicity of a widely used flame retardant.
Tris(2,3-dibromopropyl) phosphate, a widely used flame-retardant additive for textiles, is mutagenic to histidine-requiring strains of Salmonella typhimurium. Extracts of fabrics treated with this compound are also capable of inducing mutations in these bacterial strains.
D000818:Animals; D001681:Biological Assay; D003020:Clothing / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D006842:Hydrocarbons, Brominated; D008862:Microsomes, Liver / Q000378:metabolism; D009153:Mutagens; D009943:Organophosphorus Compounds / Q000009:adverse effects* / Q000378:metabolism; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects; D012867:Skin / Q000378:metabolism
D006842:Hydrocarbons, Brominated; D009153:Mutagens; D009943:Organophosphorus Compounds