Monoamine oxidase activities in patients with migraine or with cluster headache during the acute phases and after treatment with L-5-hydroxytryptophan.
The results of a study of the activity of platelet monoamine oxidase (MAO) in patients with migraine or with "Cluster headache" during the acute phases and after treatment with L-5-hydroxytryptophan are presented. MAO levels are higher in migraine subjects than in normals. There is, also, a clear difference between basal MAO levels in migraine sufferers and in Cluster Headache sufferers. The treatment with L-5-hydroxytryptophan tend to normalize MAO activity in the migraine patients, but does not change the MAO activity in cluster headache patients.
D006916:5-Hydroxytryptophan / Q000627:therapeutic use*; D000208:Acute Disease; D000328:Adult; D001792:Blood Platelets / Q000201:enzymology*; D003027:Cluster Headache / Q000188:drug therapy* / Q000201:enzymology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy* / Q000201:enzymology; D008995:Monoamine Oxidase / Q000378:metabolism*; D014653:Vascular Headaches / Q000188:drug therapy*
D006916:5-Hydroxytryptophan; D008995:Monoamine Oxidase