title: Transverse-sectional imaging with Na18F in myocardial infarction.
abstract: The potential utility of Na18F for acute infarct imaging was assessed in a canine model with a positron camera. Transverse-section imaging of radiofluoride in five dogs with acute myocardial infarction, using a multicrystal positron camera, clearly demonstrated the zones of damage as areas of increased activity. The F-18 uptake in the infarct zones was found to peak at 48 to 72 hr after coronary ligation, as does Tc-99m pyrophosphate. Preliminary in vitro studies indicate that the relative F-18 uptake, 48 after ligation, is an inverse linear function of regional blood flow.
mesh_terms: D000641:Ammonia; D000818:Animals; D004285:Dogs; D004601:Elementary Particles; D005459:Fluorides; D005461:Fluorine; D008863:Microspheres; D009203:Myocardial Infarction / Q000000981:diagnostic imaging*; D009590:Nitrogen Radioisotopes; D011868:Radioisotopes; D012538:Scandium; D012969:Sodium Fluoride; D014055:Tomography, Emission-Computed / Q000295:instrumentation
chemical_list: D009590:Nitrogen Radioisotopes; D011868:Radioisotopes; D005461:Fluorine; D000641:Ammonia; D012969:Sodium Fluoride; D005459:Fluorides; D012538:Scandium