title: Dual action of methadone on 5-HT synthesis and metabolism.
mesh_terms: D006916:5-Hydroxytryptophan / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D004295:Dihydroxyphenylalanine / Q000378:metabolism; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D008297:Male; D008691:Methadone / Q000494:pharmacology*; D009020:Morphine / Q000494:pharmacology; D009270:Naloxone / Q000494:pharmacology; D011339:Probenecid / Q000494:pharmacology; D051381:Rats; D012701:Serotonin / Q000096:biosynthesis / Q000378:metabolism*; D014364:Tryptophan / Q000378:metabolism; D014443:Tyrosine / Q000378:metabolism
chemical_list: D012701:Serotonin; D009270:Naloxone; D014443:Tyrosine; D006897:Hydroxyindoleacetic Acid; D004295:Dihydroxyphenylalanine; D009020:Morphine; D014364:Tryptophan; D006916:5-Hydroxytryptophan; D011339:Probenecid; D008691:Methadone