title: Effect of a single amino acid substitution on stability of conformation of a protein.
mesh_terms: D000595:Amino Acid Sequence; D004926:Escherichia coli / Q000201:enzymology; D006358:Hot Temperature; D009154:Mutation; D011487:Protein Conformation; D011489:Protein Denaturation / Q000187:drug effects; D013816:Thermodynamics; D014367:Tryptophan Synthase; D014508:Urea / Q000494:pharmacology; D014961:X-Ray Diffraction
chemical_list: D014508:Urea; D014367:Tryptophan Synthase