title: Iodinated silicone-an antibacterial alloplastic material.
abstract: Iodine is readily miscible in silicones and will pass freely into and out of this material at highly predictable and constant rates. Iodinated silicone is thus an effective, controlled-rate delivery system for molecular iodine. This delivery system was shown to produce bacteriostatic and bactericidal effects in vitro, and at least bacteriostatic effects in vivo. Iodinated silicone produced a protective effect against the morbidity of infection in the mouse.
mesh_terms: D000818:Animals; D001419:Bacteria / Q000187:drug effects*; D004058:Diffusion; D004926:Escherichia coli / Q000187:drug effects; D007455:Iodine / Q000494:pharmacology*; D007700:Kinetics; D051379:Mice; D008815:Mice, Inbred Strains; D008954:Models, Biological; D012828:Silicones / Q000494:pharmacology*; D013210:Staphylococcus / Q000187:drug effects
chemical_list: D012828:Silicones; D007455:Iodine