Intravitreal antimycotic therapy and the cure of mycotic endophthalmitis caused by a Paecilomyces lilacinus contaminated pseudophakos.
A salvaged eye in a case of mycotic endophthalmitis is reported. The case was one of eleven in the United States resulting from Luminex lens implants contaminated with amphotericin B resistant Paecilomyces lilacinus, and one of two eyes salvaged in this series of cases. The fungus, recognized 28 days after the lens was inserted, was in the anterior chamber, on the psuedophakos, and in the vitreous. The therapeutic procedures included removal of the pseudophakos, radical vitrectomy and iridectomy, and the intraocular and combined topical and systemic use of antimycotic compounds, including miconazole and thiabendazole.
D000368:Aged; D000935:Antifungal Agents / Q000008:administration & dosage*; D009877:Endophthalmitis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007498:Iris / Q000601:surgery; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008297:Male; D008825:Miconazole / Q000008:administration & dosage; D003904:Mitosporic Fungi; D009181:Mycoses / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D013827:Thiabendazole / Q000008:administration & dosage; D014822:Vitreous Body / Q000601:surgery
D000935:Antifungal Agents; D008825:Miconazole; D013827:Thiabendazole