title: [Mutation of bacteriophage T4 restoring phage supressor psul+ activity in bacterial strain Escherichia coli BN].
abstract: The mutant of bacteriophage T4psu1+XF2 carrying a mutational aleration in the central region of proline-serine tRNA precursor is isolated. The mutational alteration results in the recovery of amber suppressor activity of phage psu1+ serine tRNA in Escherichia coli BN in which the synthesis of this tRNA is normally blocked. Since the amber suppressor activity of mutant serine tRNA becomes sensitive to a restrictive action of strR mutations, its structure seems to be different from that of parental suppressor serine tRNA.
mesh_terms: D001483:Base Sequence; D003090:Coliphages; D004926:Escherichia coli / Q000378:metabolism; D009154:Mutation; D011392:Proline; D012343:RNA, Transfer / Q000096:biosynthesis; D012367:RNA, Viral; D011995:Recombination, Genetic; D012694:Serine; D013489:Suppression, Genetic
chemical_list: D012367:RNA, Viral; D012694:Serine; D012343:RNA, Transfer; D011392:Proline
vernacular_title: Mutatsiia bakteriofaga T4, vosstanavlivaiushchaia aktivnost' fagovogo supressora psul+, v bakterial'nom shtamme Escherichia coli BN.