title: A 3-year clinical trial of the effect on dental caries of a dentifrice containing 2% sodium monoflurophosphate.
abstract: A clinical trial of a dentifrice containing 2% sodium monofluorophosphate was carried out on 782 schoolchildren in Shropshire, England. After 3 years, a reduction of 23.8% was found in the DMFS increment obtained from clinical examination. The reduction was 38.8% using radiographs. The children were divided into three groups according to baseline DMFS. Those with a "medium" caries experience were found to benefit most from using the dentifrice. There was a difference in the effect on individual tooth sites; the approximal surfaces of the posterior teeth received the most benefit and the occlusal surfaces the least.
mesh_terms: D002648:Child; D002986:Clinical Trials as Topic; D004245:DMF Index; D003731:Dental Caries / Q000517:prevention & control*; D003802:Dentifrices; D004341:Drug Evaluation; D005260:Female; D005460:Fluorides, Topical / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010710:Phosphates / Q000627:therapeutic use*; D012964:Sodium; D013997:Time Factors
chemical_list: D003802:Dentifrices; D005460:Fluorides, Topical; D010710:Phosphates; D012964:Sodium