title: Schistosoma mansoni: ultrasonically detectable motor activity responses to 5-hydroxytryptamine in vitro.
abstract: The ultrasonic method compared favourably with other methods for monitoring schistosome motor activity in vitro, being able to detect and differentiate between the activity responses of Schistosoma mansoni to 5-hydroxytryptamine at concentrations down to 1 X (10(-6) M. This was taken to indicate suitable sensitivity for the application of the ultrasonic method to other drug studies.
mesh_terms: D006916:5-Hydroxytryptophan / Q000494:pharmacology*; D000818:Animals; D003201:Computers; D004305:Dose-Response Relationship, Drug; D005260:Female; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects*; D012550:Schistosoma mansoni / Q000187:drug effects*; D014465:Ultrasonics
chemical_list: D006916:5-Hydroxytryptophan