title: Acyl derivatives of p-aminobenzoic acid as new substrates for the assay of serum acylase activity.
abstract: A simple colorimetric method for the assay of cobalt-activated acylase activity in human serum using new and less toxic N-chloroacetyl-gamma-L-glutamyl-p-aminobenzoic acid as substrate has been described. The values obtained with this method are almost the same as with the previously described method using naphthylamide substrate.
mesh_terms: D010129:4-Aminobenzoic Acid / Q000138:chemical synthesis / Q000633:toxicity; D000581:Amidohydrolases / Q000097:blood*; D062365:Aminobenzoates; D000813:Anilides; D000818:Animals; D003035:Cobalt / Q000494:pharmacology; D003124:Colorimetry; D006525:Hepatitis, Viral, Human / Q000097:blood; D006801:Humans; D006868:Hydrolysis; D008722:Methods; D051379:Mice; D062366:para-Aminobenzoates
chemical_list: D062365:Aminobenzoates; D000813:Anilides; D062366:para-Aminobenzoates; D003035:Cobalt; D000581:Amidohydrolases; D010129:4-Aminobenzoic Acid