Microsurgical renal transplantation techniques in small animals.
The laboratory rat has been widely used as a preclinical model of renal transplantation. Surgical anastomosis of the small lumenal structures encountered requires strict adherence to basic principles of microsurgical technique. Nonfatal technical errors may adversely affect renal allograft function and influence experimental results. Experience obtained from a series of more than 600 rat renal transplants is discussed.
D000818:Animals; D004195:Disease Models, Animal; D006085:Graft Survival; D016030:Kidney Transplantation; D008866:Microsurgery / Q000379:methods*; D010477:Perfusion; D051381:Rats; D011919:Rats, Inbred Strains; D013536:Suture Techniques; D014184:Transplantation, Homologous; D001743:Urinary Bladder / Q000601:surgery