Further evaluation of the test for detection of antibody-coated bacteria in urine sediment.
To assess the reproducibility of the test for detection of antibody-coated bacteria in urine sediment as it might be used in a diagnostic laboratory for classification of urinary tract infections, multiple urine specimens from 83 patients were tested. The results were reproducible and consistent, or if inconsistent potentially explainable, in all but four patients. The explanation for inconsistencies include the immune response to the infecting bacteria, nonspecificity of the antibody coating the bacteria, antibody in prostatic secretions, and antibody-coated bacteria contaminating the urine specimens.
D000907:Antibodies, Bacterial / Q000032:analysis; D003429:Cross Reactions; D003937:Diagnosis, Differential; D004755:Enterobacteriaceae / Q000302:isolation & purification*; D004926:Escherichia coli / Q000276:immunology; D005069:Evaluation Studies as Topic; D005455:Fluorescent Antibody Technique; D006801:Humans; D007711:Klebsiella pneumoniae / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000378:metabolism; D011472:Prostatitis / Q000276:immunology; D011549:Pseudomonas / Q000302:isolation & purification*; D014552:Urinary Tract Infections / Q000175:diagnosis*; D014556:Urine / Q000382:microbiology*
D000907:Antibodies, Bacterial