Islet cell hyperplasia localized by pancreatic vein catheterization and insulin radioimmunoassay.
A patient with organic hypoglycemia but with normal pancreatic arteriography was investigated with pancreatic vein catheterization for insulin immunoassay. Very high insulin concentrations (1, 130 micronU/ml) were found in a vein draining part of the pancreatic tail. Even though no tumor was found at operation, distal hemipancreatectomy was performed according to the assay findings. Histology and immunohistochemistry revealed a localized islet hyperplasia.
D000328:Adult; D002404:Catheterization; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000097:blood / Q000175:diagnosis; D007328:Insulin / Q000097:blood*; D007515:Islets of Langerhans / Q000473:pathology*; D010179:Pancreas / Q000098:blood supply*; D011863:Radioimmunoassay; D014680:Veins
D007328:Insulin