[Effect of peptide hormones of the gastrointestinal tract on leukocytes].
A single i. m. administration of pentagastrin or secretin changed the amount of lymphoid and myeloid cells in rats and mice. A total decrease of leucocytes is due to decrease of amount of lymphocytes, eosinophiles, and monocytes. Simultaneously the amount of segment-nuclear and relating to stab neutrophiles increased. After pentagastrin administration the amount of rosette-forming T-lymphocytes decreases. The data obtained suggest the effect of gastrin and secretin on the blood-forming and blood-destroying systems of the organism.
D000818:Animals; D002452:Cell Count; D002766:Cholecystokinin / Q000494:pharmacology; D005768:Gastrointestinal Hormones / Q000494:pharmacology*; D005934:Glucagon / Q000494:pharmacology; D007962:Leukocytes / Q000187:drug effects*; D009037:Motilin / Q000494:pharmacology; D010418:Pentagastrin / Q000494:pharmacology; D051381:Rats; D012397:Rosette Formation; D012633:Secretin / Q000494:pharmacology; D013601:T-Lymphocytes / Q000187:drug effects
D005768:Gastrointestinal Hormones; D012633:Secretin; D009037:Motilin; D005934:Glucagon; D002766:Cholecystokinin; D010418:Pentagastrin
Vliianie peptidnykh gormonov zheludochno-kishechnogo trakta na kletochnye élementy beloĭ krovi.