Lymphocyte markers, serum thymic factor and IgE in IgA deficiency.
Eleven patients having a selective IgA deficiency had very low T-cell percentages assessed by using E-rosettes, active E-rosetts and an anti-human anti-T-lymphocyte antigen serum. B-cells were normal or slightly decreased. IgE concentrations were often low. Patients with serum IgA under 50 IU/ml often had elevated serum IgE values and low T-cell percentages. Serum thymic factor dosages were correlated with the E-rosette assay.
D000293:Adolescent; D000328:Adult; D000361:Agammaglobulinemia / Q000276:immunology*; D000368:Aged; D000961:Antilymphocyte Serum / Q000494:pharmacology; D001402:B-Lymphocytes / Q000276:immunology; D002648:Child; D006801:Humans; D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D007073:Immunoglobulin E / Q000276:immunology*; D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008214:Lymphocytes / Q000276:immunology*; D008875:Middle Aged; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
D000961:Antilymphocyte Serum; D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007073:Immunoglobulin E