[Cross reactions in the H-2 system of cytotoxic T-lymphocytes concentrated by the adsorption-elution method on target cell monolayers].
Cytotoxic T-lymphocytes (CTL) obtained by in vivo immunization were enriched by the absorption-elution technique, using the relevant allogeneic target cell (TC) monolayers. After the separation of C57BL anti-A (anti-KkDd) lymphocytes into anti-Kk and anti-Dd subpopulations they displayed cross killing cytotoxic effect on H-2d and H-2kTC, respectively. B10D2 anti-B10 (anti-KbDd) lymphocytes cross reacted to H-2a and H-2q TC. The results are discussed in the light of heterogeneity of CTL clones or their receptors.
D000483:Alleles; D000818:Animals; D003429:Cross Reactions; D003602:Cytotoxicity, Immunologic; D006183:H-2 Antigens / Q000235:genetics / Q000276:immunology*; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D011995:Recombination, Genetic; D013601:T-Lymphocytes / Q000276:immunology*
D006183:H-2 Antigens
Perekrestnye reaktsii v sisteme H-2 tsitotoksicheskikh T-limfotsitov, kontsentrirovannykh metodom adsorbtsii-éliutsii na monosloe kletok-misheneĭ.