Alteration in cell-mediated immunity in patients with chronic active hepatitis. I. Lymphocyte subpopulations.
Absolute number of T and B lymphocytes were measured in the peripheral blood of 25 patients with biopsy proven HBsAg-positive Chronic Active Hepatitis (CAH), in 9 with Chronic Persistent Hepatitis (CPH), and in 25 HBsAg-negative healthy controls. In patients with CAH and cirrhosis total T lymphocytes were decreased; no difference were found between patients with CPH and normal controls. This data emphasize the importance of monitoring T-cells population in patients with HBsAg-positive CAH.
D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology*; D002908:Chronic Disease; D006509:Hepatitis B / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D007111:Immunity, Cellular; D007958:Leukocyte Count; D008875:Middle Aged; D011947:Receptors, Antigen, B-Cell / Q000032:analysis; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
D006514:Hepatitis B Surface Antigens; D011947:Receptors, Antigen, B-Cell