[The removal of gastrin secreting tissue in the treatment of Zollinger-Ellison syndrome (author's transl)].
In the light of 24 cases, routine total gastrectomy in the treatment of Zollinger-Ellison's syndrome should be abandoned in favour of the removal of gastrin-secreting tissue. This treatment which gives just as good results on the ulcer disease, also has the advantage of removal of the tumour tissue malignant in almost 2/3 of cases. Removal of the gastrin secreting tissue thus becomes the operation of choice. Total gastrectomy remains a last resort operation if it proves impossible to find or remove the gastrinoma, or, if after removal of the original tumour, there occurs a relapse of the ulcers or spread of the neoplasm.
D000328:Adult; D000368:Aged; D004386:Duodenum / Q000601:surgery; D005260:Female; D005743:Gastrectomy; D005753:Gastric Mucosa / Q000378:metabolism* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000601:surgery; D010437:Peptic Ulcer / Q000601:surgery; D015043:Zollinger-Ellison Syndrome / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*
L'exérèse du tissue gastrino-secrétant dans le traitement du syndrome de Zollinger-Ellison.