[Intraspecies antagonism of Sh. flexneri in an HEp-2 cell line model].
The authors describe an effect of suppression of invasion of the guinea pig eye conjunctiva and the HEp-2 epithelial cells by virulent Sh. flexneri bacilli, with a simultaneous administration of the same dose of avirulent shigella mutants, genetically connected with them. The data of morphological study and experiments with 3H-glucose labeled shigellae carried out on the cell species model indicated that the bacterial competition for the specific sites for absorption on the epithelial cells underlay the observed phenomenon.
D000818:Animals; D000898:Antibiosis; D002460:Cell Line; D006168:Guinea Pigs; D007637:Keratoconjunctivitis / Q000209:etiology; D012763:Shigella flexneri / Q000472:pathogenicity / Q000502:physiology*; D014774:Virulence
Izuchenie vnutrividovogo antagonizma Sh. flexneri na modeli kletochnoĭ linii HEp-2.