title: [Hyposensitisation treatment with pure bee venom (author's transl)].
abstract: Hyposensitisation with pure bee venom was undertaken in eleven persons with proven allergy to bee stings. Rapid hyposensitisation led to side effects in seven of them during dosage increase. Serial determination of total IgA, IgG, IgM and alpha1-antitrypsin revealed no changes, while allergen-specific IgG and IgE and total IgE increased maximally after 30 days. All persons were exposed to one bee sting during the treatment: all tolerated it well without the allergic reactions which had previously been noted.
mesh_terms: D000293:Adolescent; D000328:Adult; D001514:Bee Venoms; D002648:Child; D003888:Desensitization, Immunologic / Q000009:adverse effects; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007073:Immunoglobulin E / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008722:Methods; D013997:Time Factors; D000515:alpha 1-Antitrypsin / Q000032:analysis
chemical_list: D001514:Bee Venoms; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D000515:alpha 1-Antitrypsin; D007073:Immunoglobulin E
vernacular_title: Die Hyposensibilisierungsbehandlung mit reinem Bienengift.