title: Contrast-enhanced lesions on computerised tomography in multiple sclerosis.
abstract: Two patients are described in whom computerised tomography revealed contrast-enhanced lesions in the early stages of multiple sclerosis. Such lesions may be differentiated from tumours by their transient nature, lack of space-occupying effect, and localisation in the white matter. Contrast enhancement in demyelinating disease is probably related to local breakdown of the blood-brain barrier.
mesh_terms: D000328:Adult; D014695:Cerebral Ventriculography; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D007483:Iothalamic Acid; D009103:Multiple Sclerosis / Q000000981:diagnostic imaging*; D010296:Parietal Lobe / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: D007483:Iothalamic Acid