Presumed chronic ocular histoplasmosis syndrome: a clinical-pathologic case report.
An eye of a patient with clinically typical presumed ocular histoplasmosis was studied by light microscopy, electron microscopy and immuno-fluorescence techniques. There was clinical and pathological evidence of anterior segment involvement. The posterior segment showed granulomatous and nongranulomatous chorioretinal lesions with and without subretinal neovascularization. Immunohistopathological staining for histoplasma antigens revealed positive staining at sites of lymphoid inflammation. Organisms were not identified.
D000328:Adult; D000941:Antigens; D002829:Choroid / Q000473:pathology; D002830:Choroid Neoplasms / Q000150:complications; D005128:Eye Diseases / Q000175:diagnosis / Q000473:pathology; D005455:Fluorescent Antibody Technique; D005654:Fundus Oculi; D006658:Histoplasma / Q000276:immunology; D006660:Histoplasmosis / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008266:Macula Lutea / Q000473:pathology; D008297:Male; D008545:Melanoma / Q000150:complications; D008875:Middle Aged; D010786:Photoreceptor Cells / Q000648:ultrastructure; D010857:Pigment Epithelium of Eye / Q000648:ultrastructure; D012171:Retinal Vessels / Q000473:pathology; D014606:Uveitis, Anterior / Q000209:etiology
D000941:Antigens