The effect of lithium on luteinizing hormone and testosterone in man.
Serum luteinizing hormone and testosterone were determined weekly during the course of a comparison of the effects of lithium versus placebo on impulsive aggressive behavior in 16-24 year-old male prisoners. The duration of drug treatment for each individual was up to 3 months. A significant reduction of serious agressive behavioral incidents occurred in the third month on lithium and was accompanied by a significant rise in serum luteinizing hormone, with no change in serum testosterone.
D000293:Adolescent; D000328:Adult; D000374:Aggression / Q000187:drug effects; D002986:Clinical Trials as Topic; D006801:Humans; D007175:Impulsive Behavior / Q000097:blood / Q000188:drug therapy*; D008094:Lithium / Q000494:pharmacology* / Q000627:therapeutic use; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D010919:Placebos; D011329:Prisoners; D013739:Testosterone / Q000097:blood*; D013997:Time Factors
D010919:Placebos; D013739:Testosterone; D007986:Luteinizing Hormone; D008094:Lithium