A comparative study of ketone body metabolism between the camel (Camelus dromedarius) and the sheep (Ovis aries).
1. Plasma levels of beta-hydroxybutyrate (BHB), and acetoacetate (AcAc) have been measured in camels (Camelus dromedarius) and sheep (Ovis aries). The activity of beta-hydroxybutyrate dehydrogenase (BHB-deH2) (E.C. 1.1.1.30) was studied in the rumen epithelium and the liver of these animals. 2. Concentrations of plasma BHB and AcAc in the camel were in respective order 33 and 4 times lower than that of the sheep. The ratios of BHB to AcAc were 0.61 and 4.8 for the camel and sheep, respectively. 3. The activity of BHB-deH2 in the rumen epithelium of the camel and sheep were 7.15 and 66 mumol/hr/g wet wt tissue, respectively. The activity in both species was higher in the rumen epithelium than in the liver.
D000090:Acetoacetates / Q000378:metabolism; D000818:Animals; D002162:Camelus / Q000378:metabolism*; D006884:Hydroxybutyrate Dehydrogenase / Q000378:metabolism; D066298:In Vitro Techniques; D007657:Ketone Bodies / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D012417:Rumen / Q000201:enzymology / Q000378:metabolism; D012756:Sheep; D013045:Species Specificity
D000090:Acetoacetates; D007657:Ketone Bodies; D006884:Hydroxybutyrate Dehydrogenase