[Regulatory role of the bone marrow in immunogenesis. 1. Bone marrow suppressor cells in the in vitro culture].
Bone marrow cells added to the spleen cell culture (after Mishell and Dutton) stimulated with sheep red blood cells suppressed the production of plaque-forming cells. Bone marrow supressors-cells bear surface immunoglobulins and MBLA, they are referred to the actively prolferating cells, and, apparently, represent immature cells-precursors of B-lymphocytic series.
D000818:Animals; D000917:Antibody Formation; D000921:Antibody-Producing Cells / Q000166:cytology / Q000276:immunology*; D001402:B-Lymphocytes / Q000166:cytology / Q000276:immunology*; D001854:Bone Marrow Cells; D002455:Cell Division; D002478:Cells, Cultured; D003165:Complement System Proteins; D003470:Culture Media; D006918:Hydroxyurea / Q000494:pharmacology; D007106:Immune Sera; D007074:Immunoglobulin G / Q000096:biosynthesis*; D007166:Immunosuppressive Agents; D066298:In Vitro Techniques; D051379:Mice; D011817:Rabbits; D012756:Sheep; D013154:Spleen / Q000166:cytology
D003470:Culture Media; D007106:Immune Sera; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D003165:Complement System Proteins; D006918:Hydroxyurea
Reguliatornaia rol' kostnogo mozga v immunogeneze. Soobschenie 1. Kostno-mozgovye kletki-supressory v kul'ture in vitro.