title: [A purified rabies vaccine from human diploid cell cultures (author's transl)].
abstract: In order to improve the tolerance of rabies vaccine from human diploid cell cultures, the rabies virus antigen is purified in the sucrose density gradient by means of a flow ultracentrifuge. The purified virus has a specific infectiosity of 10(9) LD50 and a speicific activity of 250 units "relative activity" per 1 mg protein. The purified vaccine has been shown to be well tolerated, effective and stable.
mesh_terms: D000818:Animals; D002499:Centrifugation, Density Gradient; D046508:Culture Techniques; D004171:Diploidy; D006801:Humans; D051379:Mice; D011819:Rabies Vaccines / Q000302:isolation & purification*; D013395:Sucrose
chemical_list: D011819:Rabies Vaccines; D013395:Sucrose
vernacular_title: Ein gereinigter Tollwut-Impfstoff aus menschlichen diploiden Zellkulturen.