title: [Focal epidermal necrolisis. A variation of lupus erythematosus of a new disease?].
abstract: Four cases with clinical characteristics closely related to Lupus Erythematosus Disseminatum are reported by the authors. The evolution, progress and the biochemical, immunological and photobiological data were different from those usually found in L.E.D. The histopathological picture was also dissimilar, the most characteristic finding being a sharply limited epidermal necrolysis with focal distribution. In view of the peculiarities of the clinico-pathological syndrome presented by these patients, the authors raise the questions does it represent a special modality of L.E.D. or a new lupus-like disease?
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology* / Q000473:pathology; D008297:Male; D010787:Photosensitivity Disorders / Q000175:diagnosis / Q000473:pathology; D012867:Skin / Q000473:pathology; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis / Q000276:immunology* / Q000473:pathology
vernacular_title: Necrolisis epidérmica focal una variedad de lupus eritematosos o una nueva enfermedad?