title: Studies on Theileriidae (Sporozoa) in Tanzania. VI. Second field trial on immunization against cattle theileriosis.
abstract: Nine cattle, immunized by an infection and treatment method with 3 strains of Theileria parva (Muguga, Kiambu 5 and Serengeti transformed) and nine controls, were exposed to natural tick infestation in Tanzania. All controls contracted fatal East Coast Fever within 2 months of exposure. All immunized animals survived the period of exposure (over 2 months), but later one died of ECF, one of heart-water, one of an undetermined cause (not a theileriosis), and one disappeared from the herd. The 5 remaining animals survived for over 3 months after exposure ended. It is thought that this method of immunization is of value in protecting valuable animals at risk. An attempt to immunize against pathogenic Theilereia mutans, by injecting blood containing an apathogenic strain of this parasite, gave inconclusive results as no pathogenic strains were encountered during the trial.
mesh_terms: D000818:Animals; D002417:Cattle; D004912:Erythrocytes / Q000469:parasitology; D056890:Eukaryota; D005455:Fluorescent Antibody Technique; D006400:Hematocrit; D007114:Immunization; D008198:Lymph Nodes / Q000469:parasitology; D013801:Theileriasis / Q000097:blood / Q000469:parasitology / Q000517:prevention & control*