Enzyme patterns in cancer.
The recent reports of the use of serum and tissue enzyme assays in primary diagnosis and then in following the course of the disease have been reviewed. These include use of bone marrow acid phosphatase, isoenzymes of both acid and alkaline phosphatase, LDH5/LDH1 ratios, sialyltransferase and the combination of carcinoembryonic antigen with serum enzyme assays to help in prediction of the occurrence of hepatic metastases.
D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000097:blood; D001192:Arylsulfatases / Q000378:metabolism; D001853:Bone Marrow / Q000201:enzymology; D001859:Bone Neoplasms / Q000201:enzymology; D002272:Carcinoembryonic Antigen / Q000032:analysis; D005634:Fructose-Bisphosphate Aldolase / Q000378:metabolism; D006593:Hexokinase / Q000378:metabolism; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000201:enzymology* / Q000276:immunology; D011471:Prostatic Neoplasms / Q000201:enzymology; D012799:Sialyltransferases / Q000378:metabolism
D002272:Carcinoembryonic Antigen; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D012799:Sialyltransferases; D006593:Hexokinase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D001192:Arylsulfatases; D005634:Fructose-Bisphosphate Aldolase