[Role of several physico-chemical surface properties of bacteria in the machanism of the initial phases of phagocytosis].
An attempt was made on E. coli pattern to reveal the role played by the surface charge and the extent of the surface hydration in the mechanism of the initial phagocytosis phases (attraction and submersion). Phagocytosis experiments with washed bacteria and washed rabbit leukocytes demonstrated a marked direct dependence of the electrophoretic velocities of escherichia and the intensity of their phagocytic ingestion, and a strong reverse relationship between the extent of hydration and the phagocytic activity. Treatment of bacteria with rabbit plasma with subsequent washing led to a significant reduction of hydration and to an insignificant reduction of the electrophoretic velocities with parallel increase of the phagocyte activity. Correlation between the phagocytosis intensity and the acquired physico-chemical properties of bacteria became weak.
D000327:Adsorption; D001798:Blood Proteins; D004560:Electricity; D004586:Electrophoresis; D004926:Escherichia coli; D007962:Leukocytes / Q000276:immunology; D010587:Phagocytosis; D013499:Surface Properties
D001798:Blood Proteins
O roli nekotorykh fiziko-khimicheskikh svoĭstv poverkhnosti bakteriĭ v mekhanizme nachal'nykh faz fagotsitoza