title: Is your dosage really necessary? Antibiotic dosage in urinary infection.
abstract: Dense cultures of bacteria were exposed to changing concentrations of beta-lactam antibiotics in an in-vitro model of the urinary bladder. The results suggest that uncomplicated urinary infection may respond to lower doses than are usually given without compromising the success of subsequent treatment in those cases in which such minimal treatment fails.
mesh_terms: D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage*; D002511:Cephalosporins / Q000008:administration & dosage*; D004926:Escherichia coli / Q000187:drug effects; D004927:Escherichia coli Infections / Q000188:drug therapy; D006801:Humans; D010406:Penicillins / Q000008:administration & dosage*; D011512:Proteus Infections / Q000188:drug therapy; D011513:Proteus mirabilis / Q000187:drug effects; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D000892:Anti-Infective Agents, Urinary; D002511:Cephalosporins; D010406:Penicillins