Structural studies of the Shigella flexneri variant X, type 5 a and type 5 b O-antigens.
Previous studies of different Shigella flexneri O-antigens indicate that their O-specific region is composed of oligosaccharide repeating units containing a basic tetrasaccharide structure, to which alpha-D-glucopyranosyl groups and O-acetyl groups may be attached to different positions. Structural studies of O-antigens from variant X, type 5a and type 5b lend further support to this assumption. These antigens contain terminal alpha-D-glucopyranosyl groups, one each per repeating unit in X and 5a, two in 5b. The location of these groups in the repeating unit has been determined.
D002241:Carbohydrates / Q000032:analysis; D008070:Lipopolysaccharides; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009154:Mutation; D009844:Oligosaccharides / Q000032:analysis; D011135:Polysaccharides, Bacterial; D012763:Shigella flexneri / Q000276:immunology*
D002241:Carbohydrates; D008070:Lipopolysaccharides; D009844:Oligosaccharides; D011135:Polysaccharides, Bacterial