Influence of a mycoplasma respiratory tract infection on sheep erythrocyte and complement receptor-bearing cell composition in the respiratory tract of swine.
Pulmonic and peripheral blood lymphocyte subpopulations in healthy and Mycoplasma suipneumoniae-infected pigs were compared. The T- and the B-lymphocyte populations were counted, the B cells by the complement receptor (zymosan-complement rosettes) technique and the T cells by the ED-rosette technique (sheep RBC-dextran rosettes). The T cells were found to predominate among pulmonic, as well as blood, lymphocytes. Pulmonic B-cell and blood T-cell percentages were increased after mycoplasma respiratory tract infection. However, blood B-cell and pulmonic T-cell percentages were not significantly affected. A significant (P less than 0.001) correlation between pulmonic and blood T-lymphocyte compositions was found; conversely, no correlation was observed between blood and pulmonic B-cell percentages. These data could imply that pulmonic B cells are predominantly involved in local immune reactions after a mycoplasma respiratory tract infection.
D000818:Animals; D001402:B-Lymphocytes; D008168:Lung / Q000032:analysis / Q000276:immunology; D008214:Lymphocytes / Q000145:classification*; D009175:Mycoplasma Infections / Q000097:blood / Q000662:veterinary*; D011951:Receptors, Complement / Q000032:analysis*; D012137:Respiratory System / Q000276:immunology*; D012141:Respiratory Tract Infections / Q000276:immunology / Q000662:veterinary*; D012397:Rosette Formation; D012756:Sheep / Q000276:immunology; D013552:Swine; D013553:Swine Diseases / Q000276:immunology*; D013601:T-Lymphocytes
D011951:Receptors, Complement