title: The role of the septal area in the neuroendocrine control of growth in the adult golden hamster.
abstract: Somatic, endocrine and behavioral correlates of growth were measured in intact and hypophysectomized adult hamsters with or without electrolytic damage to the rostral septal area. Septal (SEP) lesions significantly increased somatic growth rate, food consumption and serum concentration of growth hormone (GH) and insulin. Pituitary GH content and concentration were reduced in lesioned hamsters. None of these changes were found in hypophysectomized hamsters with SEP lesions. SEP lesions did not affect the percentage of body fat. These data suggest that the septum or adjacent fibers of passage inhibit growth in adult hamsters.
mesh_terms: D000818:Animals; D001827:Body Height; D001835:Body Weight; D001921:Brain / Q000033:anatomy & histology / Q000502:physiology*; D006224:Cricetinae; D004327:Drinking Behavior / Q000502:physiology; D004564:Electrocoagulation; D005247:Feeding Behavior / Q000502:physiology; D005260:Female; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism; D007016:Hypophysectomy; D007328:Insulin / Q000097:blood; D008647:Mesocricetus; D009490:Neurosecretory Systems / Q000502:physiology*; D010903:Pituitary Gland, Anterior / Q000378:metabolism; D013238:Stereotaxic Techniques
chemical_list: D007328:Insulin; D013006:Growth Hormone