[Vestibular toxicity of gentamycin: value of the galvanic test (author's transl)].
A total of 6 cases of bilateral vestibular areflexia due to Gentamycin are reported. Vestibular destruction was associated with deafness in only 3 of the patients. Two patients had no signs of renal insufficiency. Galvanic vestibular exploration showed complete and bilateral lack of excitability in 3 out of 4 cases, which could be due to the co-existence of nerve or nuclei lesions. In one case, galvanic excitability was within normal limits, and severe equilibrium problems presisted. The presence of an asymmetry on galvanic examination could be an unfavourable prognostic sign in vestibular toxicity due to Gentamycin.
D000328:Adult; D000368:Aged; D005260:Female; D005712:Galvanic Skin Response; D005839:Gentamicins / Q000009:adverse effects*; D006801:Humans; D007759:Labyrinth Diseases / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D004856:Postural Balance / Q000187:drug effects; D012021:Reflex, Abnormal / Q000139:chemically induced; D014725:Vestibular Nerve / Q000187:drug effects; D014726:Vestibular Nuclei / Q000187:drug effects; D014722:Vestibule, Labyrinth / Q000187:drug effects*
D005839:Gentamicins
Toxicité vestibulaire de la gentamycine: intérêt de l'épreuve galvanique.