Failure to respond to influenza vaccine in the aged: correlation with B-cell number and function.
Failure to respond to influenza vaccination correlated with a decreased number and percentage of IgD-bearing PBL and a dampened lymphocyte response to PWM in a subset of healthy aged volunteers. These subjects had normal levels of serum immunoglobulins, intact T cell function, and normal numbers of E-rosetting cells.
D000367:Age Factors; D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology*; D006801:Humans; D007114:Immunization; D007072:Immunoglobulin D; D007075:Immunoglobulin M; D007252:Influenza Vaccines / Q000276:immunology / Q000627:therapeutic use*; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology
D007072:Immunoglobulin D; D007075:Immunoglobulin M; D007252:Influenza Vaccines