Accumulation of deoxyribonucleotides as a possible mediator of immunosuppression in hereditary deficiency of adenosine deaminase.
D000243:Adenosine Deaminase / Q000172:deficiency*; D002455:Cell Division / Q000187:drug effects; D003838:Deoxyadenine Nucleotides / Q000378:metabolism; D003839:Deoxyadenosines / Q000378:metabolism / Q000494:pharmacology; D003854:Deoxyribonucleotides / Q000378:metabolism*; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000378:metabolism*; D007165:Immunosuppression Therapy; D008213:Lymphocyte Activation / Q000187:drug effects; D009700:Nucleoside Deaminases / Q000172:deficiency*; D013601:T-Lymphocytes / Q000276:immunology
D003838:Deoxyadenine Nucleotides; D003839:Deoxyadenosines; D003854:Deoxyribonucleotides; D009700:Nucleoside Deaminases; D000243:Adenosine Deaminase