title: Proplast in the middle ear and oval window of cats.
abstract: Poly(tetrafluoroethylene) carbon fiber implant material (Proplast), an all-plastic material, was evaluated for use in otologic surgery. Response to the implant was studied in the middle ear and vestibule of 14 cats by placing the Proplast in the oval window after stapedectomy. After a one year follow-up, it appears that Proplast was tolerated well, causing no inflammatory reaction in either the vestibule or cochlea, or in the middle ear cavity. Fibrous tissue ingrowth was found throughout the implant, and a fibrous tissue membrane covered both the vestibular and the tympanic surfaces of the Proplast. Being well tolerated by both middle ear and inner ear tissues, this porous, all-plastic material offers several otologic applications.
mesh_terms: D000818:Animals; D002244:Carbon / Q000627:therapeutic use*; D002415:Cats; D004432:Ear, Middle / Q000473:pathology / Q000601:surgery*; D005549:Foreign-Body Reaction / Q000473:pathology; D011138:Polytetrafluoroethylene / Q000627:therapeutic use*; D019736:Prostheses and Implants; D014722:Vestibule, Labyrinth / Q000473:pathology / Q000601:surgery*
chemical_list: D002244:Carbon; D011138:Polytetrafluoroethylene