title: [Duodenal ulcer therapy with cimetidine. A clinical endoscopic study in 76 patients (author's transl)].
abstract: 34 patients were treated with cimetidine and placebo in a double blind trial and 42 were treated with cimetidine alone. Criteria investigated were the pain response, consumption of antacids when required and especially the endoscopically demonstrated scarring of the duodenal ulcer. Compared with placebo, cimetidine is capable of soothing pain and also reducing the consumption of antacids more quickly and to a greater extent. The differences are statistically significant. Complete anatomical healing of the ulcer was established in the double blind study in 80% of the patients in the cimetidine group and in 40% of the placebo group. Similar results were also shown in the group which received cimetidine alone.
mesh_terms: D002927:Cimetidine / Q000627:therapeutic use*; D004311:Double-Blind Method; D004381:Duodenal Ulcer / Q000188:drug therapy*; D004386:Duodenum; D004724:Endoscopy; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D010919:Placebos
chemical_list: D006146:Guanidines; D010919:Placebos; D002927:Cimetidine
vernacular_title: Therapie mit Cimetidin beim Ulcus duodeni. Klinisch-endoskopische Studie an 76 Patienten.