Naturally occurring plasmid carrying genes for enterotoxin production and drug resistance.
Escherichia coli strain 86, isolated from a piglet with diarrhea, carries plasmid-linked genes for resistance to tetracycline, streptomycin, and sulfonamides and for production of heat-labile and heat-stable enterotoxin. Results of (i) genetic experiments involving conjugal transfer and phage P1-mediated transduction and (ii) physical experiments involving electron microscopic examination of plasmid DNA and heteroduplex analysis show that a single conjugative plasmid carries the genes for drug resistance and production of enterotoxin.
D003227:Conjugation, Genetic; D004269:DNA, Bacterial / Q000378:metabolism; D004768:Enterotoxins / Q000096:biosynthesis*; D004926:Escherichia coli / Q000378:metabolism*; D005796:Genes; D008040:Genetic Linkage; D008970:Molecular Weight; D010957:Plasmids; D011815:R Factors; D013045:Species Specificity; D014161:Transduction, Genetic
D004269:DNA, Bacterial; D004768:Enterotoxins