Kartagener syndrome with abnormalities of cilia.
Kartagener syndrome of sinusitis, bronchiectasis and situs inversus has been so called since his classical description in 1933. This report presents two further cases, a brother and sister. They were extensively studied and the findings are reported. A unique finding was that in both patients, both in the maxillary sinuses and in the bronchi, abnormal cilia were discovered on electron microscopy. After a search of the literature the authors conclude that this finding is probably congenital rather than acquired and may explain the development of the sinusitis and bronchiectasis.
D000293:Adolescent; D000368:Aged; D001980:Bronchi / Q000473:pathology* / Q000648:ultrastructure; D001987:Bronchiectasis / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D002923:Cilia / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007223:Infant; D007619:Kartagener Syndrome / Q000235:genetics / Q000473:pathology*; D008297:Male; D008443:Maxillary Sinus / Q000473:pathology* / Q000648:ultrastructure; D009092:Mucous Membrane / Q000473:pathology / Q000648:ultrastructure; D012852:Sinusitis / Q000473:pathology