title: Clinical significance of 99mtechnetium sulfur colloid accumulation in renal transplant patients.
abstract: The accumulation of 99mtechnetium sulfur colloid (99mTcSC) was evaluated in 47 studies performed on 19 renal transplant patients by comparing its transplant activity to its bone marrow accumulation. There was a diagnosis of rejection of 21 of 22 studies (96.5%) in which marked transplant accumulation was noted. In 11 studies of patients with a clinical diagnosis of post-transplant acute tubular necrosis (ATN), the transplant activity varied from none to moderate. Rejection developed in 5 of 6 studies with minimal to moderate accumulation. Normally functioning renal transplant patients, or those with ATN and no superimposed rejection, do not show evidence of 99mTcSC accumulation.
mesh_terms: D000293:Adolescent; D000328:Adult; D002102:Cadaver; D003102:Colloids; D005260:Female; D006084:Graft Rejection; D006801:Humans; D016030:Kidney Transplantation; D007683:Kidney Tubular Necrosis, Acute / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis; D011877:Radionuclide Imaging; D012078:Renal Artery Obstruction / Q000175:diagnosis; D013455:Sulfur; D013667:Technetium; D013927:Thrombosis / Q000175:diagnosis; D014184:Transplantation, Homologous
chemical_list: D003102:Colloids; D013455:Sulfur; D013667:Technetium