Serotonin receptors on astrocytes in primary cultures: effects of methysergide and fluoxetine.
A specific binding of serotonin (at least 50 fmol/mg protein) was demonstrated in mouse astrocytes in primary cultures. This binding was inhibited by methysergide and by fluoxetine.
D000818:Animals; D001253:Astrocytes / Q000378:metabolism*; D002478:Cells, Cultured; D005473:Fluoxetine / Q000494:pharmacology*; D008784:Methysergide / Q000494:pharmacology*; D051379:Mice; D011437:Propylamines / Q000494:pharmacology*; D011485:Protein Binding / Q000187:drug effects; D011985:Receptors, Serotonin / Q000187:drug effects / Q000378:metabolism*
D011437:Propylamines; D011985:Receptors, Serotonin; D005473:Fluoxetine; D008784:Methysergide