title: Metronidazole in prevention and treatment of bacteroides infections in elective colonic surgery.
abstract: A double-blind randomised trial was carried out among 46 patients undergoing elective colonic surgery; 27 patients received prophylactic metronidazole and 19 received placebo. Anaerobic infections did not develop in any of the metronidazole-treated patients, but did develop in 11 (58%) of 19 controls who were subsequently successfully treated with metronidazole.
mesh_terms: D001424:Bacterial Infections / Q000453:epidemiology; D001442:Bacteroides Infections / Q000517:prevention & control*; D002986:Clinical Trials as Topic; D003106:Colon / Q000601:surgery*; D006089:Gram-Negative Anaerobic Bacteria; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*
chemical_list: D008795:Metronidazole