Surface immunoglobulins on stimulated lymphocytes.
The effect of phytohaemagglutinin, lipopolysaccharide, lipid A and streptococcal erythrogenic toxin on the expression of surface immunoglobulins on nerborn piglet spleen lymphocytes was studied, using iodinated anti-pig Ig, L-, mu- or gamma-antisera. It has been concluded that only IgM is the surface immunoglobulin on non-stimulated as well as LPS-stimulated piglet lymphoid cells. An increase in the numberof labelled cells was observed after cultivation of piglet spleen cells with all the mitogens tested.
D000818:Animals; D000831:Animals, Newborn; D001427:Bacterial Toxins / Q000494:pharmacology; D002462:Cell Membrane / Q000276:immunology; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D066298:In Vitro Techniques; D037102:Lectins / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000494:pharmacology; D008214:Lymphocytes / Q000276:immunology*; D008934:Mitogens / Q000494:pharmacology*; D013297:Streptococcus pyogenes; D013552:Swine
D001427:Bacterial Toxins; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D037102:Lectins; D008070:Lipopolysaccharides; D008934:Mitogens