title: Elution of renal antischistosome antibodies in human schistosomiasis mansoni.
abstract: Elution of complexed immunoglobulins was carried out in renal tissue obtained at autopsy from schistosomiasis mansoni and control cases. Substantial amounts of IgG were found in acid eluates of 2 of 5 schistosomiasis cases and 2 of 3 controls. The IgG from schistosomiasis cases produced specific indirect immunofluorescence reactions in gut and tegument of sections of adult Schistosoma mansoni; no reactivity was present against egg granulomas, cercariae, or mouse liver tissue. Control case eluates produced no fluorescence with S. mansoni antigens.
mesh_terms: D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D000941:Antigens; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G; D007668:Kidney / Q000276:immunology* / Q000473:pathology; D012550:Schistosoma mansoni / Q000276:immunology; D012552:Schistosomiasis / Q000276:immunology* / Q000473:pathology
chemical_list: D000888:Antibodies, Anti-Idiotypic; D000941:Antigens; D007074:Immunoglobulin G