title: [Studies on the antihypertensive effect of metoprolol in practice. Results of a cooperative study by 1296 general practitioners (author's transl)].
abstract: A study with the beta1-selective adrenergic receptor blocker metoprolol in general practice was carried out by 1296 practitioners and internists. The results in 10.088 hypertensive patients were analyzed with regard to 1.9 million separate data. 200 mg metoprolol lowered the blood pressure by 25/12 mm Hg, the pulse rate fell by an average of 8 beats per minute within 6 weeks. Metoprolol was well tolerated and the relatively rare side-effects decreased in the course of the 6 weeks' therapy.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D002648:Child; D004361:Drug Tolerance; D005194:Family Practice; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008790:Metoprolol / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D011412:Propanolamines / Q000627:therapeutic use*; D011674:Pulse / Q000187:drug effects; D013997:Time Factors
chemical_list: D011412:Propanolamines; D008790:Metoprolol
vernacular_title: Untersuchungen über die antihypertensive Wirkung von Metoprolol in der Praxis. Ergebnisse einer Gemeinschaftsstudie von 1296 praktizierenden Arzten.