title: Utilization of acetate by chick brain during postnatal maturation.
abstract: 1. The study of the compartmentation of glutamate metabolism has been performed in the chick brain in vivo and in vitro in the presence of [U-14C]acetate between day 1 and day 30 of postnatal maturation. 2. The compartmentation of glutamate metabolism in vivo appears between day 1 and day 4 after hatching in the cerebral hemispheres and optic lobes. It is however more precocious in the optic lobes. In the cerebellum, it appears later, at about day 4 after hatching. The compartmentation of glutamate metabolism appears at the same time as the rapid incorporation of glucose into amino acids takes place in the cerebral hemispheres and the optic lobes. 3. In the chick telencephalon in vitro, the compartmentation of glutamate metabolism is visible from day 1 after hatching onwards. This difference is undoubtedly linked to the absence of an interference of glucose metabolism with acetate metabolism in vitro, and to the presence of a third compartment in the cerebral slices.
mesh_terms: D000085:Acetates / Q000378:metabolism*; D000375:Aging; D000596:Amino Acids / Q000096:biosynthesis; D000818:Animals; D001921:Brain / Q000254:growth & development* / Q000378:metabolism; D002645:Chickens
chemical_list: D000085:Acetates; D000596:Amino Acids