[Coagulation analytical studies in coli enterotoxemia in swine].
Store pigs with spontaneous outbreaks and experimental endotoxin shock were kept under observation in the context of coagulation analysis. Heparin was applied to some of the animals to disrupt the plasmatic coagulation system. The thrombocyte count in animals with endotoxin infusion declined by some 50 to 65 percent of the original level. No statistically secured difference was found to exist between heparinised animals, on the one hand, and non-heparinised, on the other. The aggregation and adhesion of thrombocytes in all shock animals was more pronounced than that in the controls. The fibrinogen levels were lowered in both the animals with spontaneous outbreaks and the experimental animals. Thrombocyte alteration was not found to have been dependent on activation of the plasmatic coagulation system. In endotoxin shock cases activation of plasmatic coagulation proteins was found to be preceded by rise in thrombocyte aggregation.
D000818:Animals; D001772:Blood Cell Count; D001777:Blood Coagulation / Q000187:drug effects; D001792:Blood Platelets; D003015:Clostridium Infections / Q000662:veterinary*; D004767:Enterotoxemia / Q000662:veterinary*; D004927:Escherichia coli Infections / Q000662:veterinary*; D005340:Fibrinogen / Q000032:analysis; D006493:Heparin; D010973:Platelet Adhesiveness; D010974:Platelet Aggregation; D012772:Shock, Septic / Q000097:blood; D013552:Swine; D013553:Swine Diseases / Q000097:blood*
D005340:Fibrinogen; D006493:Heparin
Gerinnungsanalytische Untersuchungen bei Kolienterotoxämie der Schweine