Effects of monochromatic X-radiation on the membrane of nodes of Ranvier under voltage and current clamp conditions.
Monochromatic Ag-Ka-radiation decreased irreversibly the peak sodium current in nodes of Ranvier. This decrease occurs only with a delay of about 1000 sec after a threshold dose of about 8 kR has been reached. Potassium current and resting potential are practically not affected.
D000818:Animals; D001001:Anura; D008564:Membrane Potentials / Q000187:drug effects / Q000528:radiation effects; D011188:Potassium / Q000494:pharmacology*; D011893:Rana esculenta; D011901:Ranvier's Nodes / Q000502:physiology / Q000528:radiation effects*; D012584:Sciatic Nerve / Q000502:physiology / Q000528:radiation effects
D011188:Potassium