An experimental model of tryptic haemorrhagic enteropathy of the dog.
To study the enteropathy characteristics of the shock state of the dog a simple experimental model has been developed. The cranial mesenteric artery was perfused with 2 micrograms/kg/min norepinephrine for an hour via a diagnostic cardiac catheter inserted under fluoroscopic control. This caused a "pharmacological occlusion" of the artery by local alpha receptor stimulation, and tryptic haemorrhagic enteritis was produced without hypovolaemia or assay operative procedure.
D000818:Animals; D004285:Dogs; D004751:Enteritis / Q000139:chemically induced / Q000209:etiology*; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced / Q000209:etiology*; D009638:Norepinephrine / Q000633:toxicity*; D012769:Shock / Q000150:complications*; D013577:Syndrome; D014357:Trypsin
D014357:Trypsin; D009638:Norepinephrine