Ubiquity of R factor-mediated antibiotic resistance in the healthy population.
An attempt was made to assess the occurrence of R factor-mediated antibiotic resistance in the healthy population. Samples of aerobic, gram-negative intestinal bacteria from men from various parts of the country at military conscription were analysed for transferable drug resistance. The obtained frequency, about 15% of R factor carriers in the studied group, was interpreted to reflect the existence of a reservoir of R factors, from which resistant, pathogenic bacteria could be selected under antibiotic therapy. Resistance to tetracycline, streptomycin and sulfonamides dominated among the identified R factor-borne resistance traits.
D000328:Adult; D001419:Bacteria / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D007709:Klebsiella / Q000187:drug effects; D008297:Male; D011815:R Factors; D013307:Streptomycin / Q000494:pharmacology*; D013449:Sulfonamides / Q000494:pharmacology*; D013752:Tetracycline / Q000494:pharmacology*
D013449:Sulfonamides; D013752:Tetracycline; D013307:Streptomycin