Further potential sources of energy modifying the multiplication of Mycobacterium leprae.
The multiplication of Mycobacterium leprae was modified by graded dilutions of organic acids. 0.01%-0.05% gluconic acid inhibited its multiplication. 0.005% of it promoted the growth of 2 out of 6 strains. 0.2% - 1.0% glucuronic acid promoted the multiplication of the majority of strains. 2.0% inhibited their multiplication, and 0.05% promoted the growth of one strain. Galacturonic and pyruvic acids were active in 0.2 - 2.0% concentrations, while the activity of citric acid was mainly noted at 1.0 and 2.0% concentrations.
D002454:Cell Differentiation / Q000187:drug effects; D002951:Citrates / Q000494:pharmacology; D003470:Culture Media; D005942:Gluconates / Q000494:pharmacology; D005965:Glucuronates / Q000494:pharmacology; D009166:Mycobacterium leprae / Q000254:growth & development*; D011773:Pyruvates / Q000494:pharmacology
D002951:Citrates; D003470:Culture Media; D005942:Gluconates; D005965:Glucuronates; D011773:Pyruvates