title: Acute ascending polyradiculoneuritis in a case of Creutzfeldt-Jakob disease.
abstract: A patient is described who showed subacute dementia and ataxia and, finally, acute asending polyradiculoneuritis. At necropsy, together with the cerebral and cerebellar lesions that are typical of Creutzfeldt-Jakob disease, the lesions of the spinal motor neurons, the spinal ganglia, and of the roots and peripheral nerves were analogous with those of the Guillain-Barré-Landry syndrome. The aetiological possibility is discussed either that this is a simple and unique association, or that the disorder is related to the virus nature of Creutzfeldt-Jakob disease.
mesh_terms: D000208:Acute Disease; D000328:Adult; D002540:Cerebral Cortex / Q000648:ultrastructure; D007562:Creutzfeldt-Jakob Syndrome / Q000150:complications* / Q000473:pathology; D005260:Female; D005625:Frontal Lobe / Q000648:ultrastructure; D005727:Ganglia, Spinal / Q000648:ultrastructure; D006801:Humans; D011128:Polyradiculopathy / Q000150:complications* / Q000473:pathology; D013788:Thalamus / Q000648:ultrastructure