Recent developments in suicide substrates and other active site-directed inactivating agents of specific target enzymes.
D000114:Acetylene / Q000494:pharmacology; D000345:Affinity Labels; D000480:Alkynes; D000590:Amino Acid Chloromethyl Ketones; D000594:Amino Acid Oxidoreductases / Q000037:antagonists & inhibitors; D000818:Animals; D001665:Binding Sites; D002918:Chymotrypsin / Q000037:antagonists & inhibitors; D004791:Enzyme Inhibitors / Q000378:metabolism*; D004988:Ethers, Cyclic / Q000494:pharmacology; D006801:Humans; D007535:Isomerases / Q000037:antagonists & inhibitors; D007700:Kinetics; D008956:Models, Chemical; D008996:Monoamine Oxidase Inhibitors; D009570:Nitriles / Q000494:pharmacology; D010088:Oxidoreductases / Q000037:antagonists & inhibitors; D010777:Photochemistry; D047428:Protein Kinase Inhibitors; D011732:Pyridoxal Phosphate / Q000494:pharmacology; D013329:Structure-Activity Relationship; D000637:Transaminases / Q000037:antagonists & inhibitors; D014361:Trypsin Inhibitors / Q000378:metabolism; D014753:Vinyl Compounds / Q000494:pharmacology
D000345:Affinity Labels; D000480:Alkynes; D000590:Amino Acid Chloromethyl Ketones; D004791:Enzyme Inhibitors; D004988:Ethers, Cyclic; D008996:Monoamine Oxidase Inhibitors; D009570:Nitriles; D047428:Protein Kinase Inhibitors; D014361:Trypsin Inhibitors; D014753:Vinyl Compounds; D011732:Pyridoxal Phosphate; D010088:Oxidoreductases; D000594:Amino Acid Oxidoreductases; D000637:Transaminases; D002918:Chymotrypsin; D007535:Isomerases; D000114:Acetylene