[Synthesis of 2,6-substituted derivatives of 5H-1.3.4-thiadiazolo[3,2a]-s-triazine-5,7-dione].
The synthesis of derivatives of 5H-1,3,4-thiadiazolo[3,2-a]-s-triazine-5,7-dione substituted in position 2 and 6 is described. The compounds were subjected to pharmacological screening, and some were found to possess antiinflammatory and antipyretic properties.
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis; D007213:Indomethacin / Q000494:pharmacology; D008297:Male; D051381:Rats; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D014227:Triazines / Q000138:chemical synthesis* / Q000494:pharmacology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D013830:Thiadiazoles; D014227:Triazines; D007213:Indomethacin
Sintesi di derivati 2,6-sostituiti del 5H-1,3,4-tiadiazolo[3,2-a]-s-triazina-5,7-dione.