title: Relation of canrenone to the actions of spironolactone on adrenal cytochrome P-450 dependent enzymes.
mesh_terms: D000311:Adrenal Glands / Q000187:drug effects / Q000201:enzymology*; D000818:Animals; D002192:Canrenone / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D005037:Ethylmorphine-N-Demethylase / Q000378:metabolism; D006168:Guinea Pigs; D008297:Male; D008861:Microsomes / Q000201:enzymology; D008928:Mitochondria / Q000201:enzymology; D006899:Mixed Function Oxygenases / Q000378:metabolism; D011245:Pregnadienes / Q000494:pharmacology*; D013148:Spironolactone / Q000494:pharmacology*; D013252:Steroid 11-beta-Hydroxylase / Q000378:metabolism; D013255:Steroid 21-Hydroxylase / Q000378:metabolism
chemical_list: D011245:Pregnadienes; D013148:Spironolactone; D002192:Canrenone; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D013255:Steroid 21-Hydroxylase; D013252:Steroid 11-beta-Hydroxylase; D005037:Ethylmorphine-N-Demethylase