title: [Identification of 3 genes in the F-plasmid of Escherichia coli K-12].
abstract: The F'argG plasmid and its two transfer-deficient (tra-) analogues have been used to analyse the pleiotropic effect of a mutation in the integrated F-factor of HfrC strain. This mutation has been shown to disturb the functioning of at least three plasmid genes constituting, probably, a single regulon: the rsf gene determining the production of recombination-stimulating factor via conjugation (RSF); the prt gene responsible for the protective effect of the plasmid against N-methyl-N'-nitro-N-nitrosoguanidine, methyl methanesulphonate and UV-irradiation; the rep gene the product of which can be involved in the control of Hfr-chromosome replication. Possible location and order of the genes in the F-plasmid are discussed.
mesh_terms: D003090:Coliphages; D004269:DNA, Bacterial / Q000096:biosynthesis / Q000302:isolation & purification; D004926:Escherichia coli / Q000254:growth & development / Q000378:metabolism; D005796:Genes; D006358:Hot Temperature; D009154:Mutation; D012343:RNA, Transfer; D012367:RNA, Viral
chemical_list: D004269:DNA, Bacterial; D012367:RNA, Viral; D012343:RNA, Transfer
vernacular_title: Identifikatsiia trekh genov v F-plazmide Escherichia coli K-12.