The effect of oral isoniazid on human lymphocyte subpopulations.
After oral administration of isoniazid (INH) to volunteers, a significant reduction in circulating T lymphocytes and a significant increase in B lymphocytes was found. These findings suggest that INH may be useful as an immunosuppressive agent.
D000328:Adult; D001402:B-Lymphocytes / Q000187:drug effects*; D002965:Classification; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000494:pharmacology*; D007958:Leukocyte Count; D008297:Male; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000187:drug effects*
D007538:Isoniazid