Disappearance of pregnancy-specific beta 1 glycoprotein from the maternal circulation after delivery.
It is likely that there are systematic differences between circulating pregnancy-specific beta 1 glycoprotein (SP1) levels measured by radioimmunoassay and immunoprecipitation systems. We have re-investigated the decline in circulating levels of SP1 following delivery of the placenta. Serial blood samples were collected for 120 hours from 10 women following Caesarean section or vaginal delivery at term. The apparent half-life of SP1 after delivery ranged between 17 and 45 hours.
D005260:Female; D006207:Half-Life; D006801:Humans; D010920:Placenta; D049590:Postpartum Period; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000378:metabolism*; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000378:metabolism*; D011863:Radioimmunoassay
D011257:Pregnancy Proteins; D011268:Pregnancy-Specific beta 1-Glycoproteins