Antipyretic action of mepacrine without blockade of prostaglandin (PG) synthesis in the C.N.S.
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D007213:Indomethacin / Q000494:pharmacology; D008297:Male; D010433:Pentylenetetrazole / Q000494:pharmacology; D011453:Prostaglandins / Q000096:biosynthesis*; D011460:Prostaglandins F / Q000096:biosynthesis; D011796:Quinacrine / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011453:Prostaglandins; D011460:Prostaglandins F; D011796:Quinacrine; D010433:Pentylenetetrazole; D007213:Indomethacin