Galactose utilization by the rat tapeworm, Hymenolepis diminuta.
1. Hymenolepis diminuta incorporated label from 14C-galactose into glycogen, but the sugar would not support net glycogen synthesis. Glucose stimulated the incorporation of label from 14C-galactose into glycogen, while glycerol did not. 2. During incubations in galactose, large internal pools of galactose and galactose 1-P accumulated, while the concentration of glucose 6-phosphate remained unchanged. 3. In vitro culture experiments indicated that galactose would not support worm growth. Therefore, while galactose can be metabolized to a limited extent, it cannot substitute for glucose as a nutrient source.
D000818:Animals; D001834:Body Water / Q000187:drug effects / Q000378:metabolism; D004040:Dietary Carbohydrates / Q000378:metabolism / Q000494:pharmacology; D004734:Energy Metabolism; D005690:Galactose / Q000378:metabolism* / Q000494:pharmacology; D005947:Glucose / Q000378:metabolism / Q000494:pharmacology; D006003:Glycogen / Q000096:biosynthesis; D006926:Hymenolepis / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*
D004040:Dietary Carbohydrates; D006003:Glycogen; D005947:Glucose; D005690:Galactose