Lymphocytes forming stable E-rosettes in acute and chronic hepatitis.
Lymphocytes forming E-rosettes with sheep erythrocytes which do not disintegrate at 37 degrees C have been demonstrated in increased numbers in peripheral blood of patients with acute type B hepatitis (6--20% of lymphocytes) and with HBsAg negative active chronic hepatitis (9--28% of lymphocytes). They were not increased in patients with HBsAg positive active chronic hepatitis. Such lymphocytes were adherent to nylon wool and a large proportion of them had FcIgG receptors (21--69%). These are properties of a subpopulation of T lymphocytes having suppressor function.
D000328:Adult; D002448:Cell Adhesion; D002462:Cell Membrane / Q000276:immunology; D002648:Child; D005260:Female; D006505:Hepatitis / Q000276:immunology*; D006509:Hepatitis B / Q000276:immunology; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000276:immunology; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*; D013696:Temperature
D007141:Immunoglobulin Fc Fragments