Noonan's syndrome and cyanotic congenital heart disease. A report of 4 cases and review of the literature.
The clinical features of four adult patients with Noonan's syndrome and cyanotic congenital heart disease are presented. These findings, together with those of previously reported cases, illustrate the wide spectrum of cardiac anomalies that may be associated with the multiple somatic abnormalities of Noonan's syndrome.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004541:Eisenmenger Complex / Q000150:complications; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications*; D006344:Heart Septal Defects, Atrial / Q000150:complications; D006345:Heart Septal Defects, Ventricular / Q000150:complications; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications; D007223:Infant; D008297:Male; D009634:Noonan Syndrome / Q000150:complications*