title: Mutagenicity of nitrovin--a nitrofuran feed additive.
abstract: Nitrovin, a nitrofuran feed additive, is shown to be directly mutagenic in Salmonella typhimurium TA 98 and TA 100 between 0.1 and 2.5 microgram per plate (0.09--2.3 micrometer). Addition of a rat-liver homogenate reduces the mutation rates. Nitrovin inhibits growth of the same bacteria in suspension cultures at concentrations above 0.09 micrometer.
mesh_terms: D000821:Animal Feed; D000818:Animals; D005503:Food Additives / Q000494:pharmacology; D008099:Liver / Q000201:enzymology; D008297:Male; D009153:Mutagens; D009154:Mutation; D009581:Nitrofurans / Q000494:pharmacology*; D009610:Nitrovin / Q000494:pharmacology*; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects
chemical_list: D005503:Food Additives; D009153:Mutagens; D009581:Nitrofurans; D009610:Nitrovin