Some observations on the in vivo effect of propranolol on platelet aggregation and release.
Platelet function was investigated in four normal volunteers, one patient with a mild form of von Willebrand disease, and one with a thrombocytopathy, all taking propranolol. No effect on platelet function attributable to this drug could be demonstrated in any of these subjects. It is suggested that propranolol administered in conventional doses does not impair platelet hemostatic function.
D000328:Adult; D001791:Blood Platelet Disorders / Q000097:blood; D001792:Blood Platelets / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects*; D011433:Propranolol / Q000494:pharmacology*; D014842:von Willebrand Diseases / Q000097:blood
D011433:Propranolol