title: A T-cell marker in mouse fibroblast x T-lymphocyte somatic cell hybrids.
abstract: Continuous hybrid cell lines have been generated by the fusion of allogeneically primed murine T lymphocytes with mouse L-cell-derived fibroblasts of the line 613. The resulting hybrid clones express one or more T-cell-specific surface components identifiable by radioiodination of intact cells followed by NP-40 solubilization of membrane proteins and sodium dodecyl sulfate polyacrylamide gel electrophoresis. These markers are stably expressed by the hybrid lines after several months of passage.
mesh_terms: D000818:Animals; D002999:Clone Cells / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D005347:Fibroblasts / Q000276:immunology; D005692:Galactose Oxidase / Q000378:metabolism; D006822:Hybrid Cells / Q000276:immunology*; D007457:Iodine Radioisotopes; D007784:Lactoperoxidase / Q000378:metabolism; D051379:Mice; D008815:Mice, Inbred Strains; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D007457:Iodine Radioisotopes; D005692:Galactose Oxidase; D007784:Lactoperoxidase