title: [Clinical significance of circulating autoantibodies].
abstract: Indirect immunofluorescence on cryostat sections of rat, baboon and human organs is the best technique for routin detection of organ specific antibodies. Most of these antibodies (antinuclear, antinucleolar, anti-mitochondria, anti-parietal cells, anti-microsomes, anti-reticulin, anti-thyroglobulin, anti-salivary gland) are detected in less than 1% of normal adults ar a titer of 1/5. Their detection at high titers is of high clinical significance.
mesh_terms: D000818:Animals; D000974:Antibodies, Antinuclear / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D006801:Humans; D051381:Rats; D012155:Reticulin / Q000276:immunology
chemical_list: D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D012155:Reticulin
vernacular_title: Valeur diagnostique des signes humoraux d'autoimmunisation