title: Kynurenine hydroxylase in Musca domestica L.
abstract: 1. Kynurenine hydroxylase activity was assayed in extracts of Musca domestica L. 2. During the life cycle of the fly, there is a peak of enzyme activity shortly after pupation. 3. Eye-color mutants, rb2, rb1; rb2 and cm, show reduced activity during pupal stages. 4. An ocra mutant lacks this activity. 5. The rb1 and rb2 mutations were separated from the rb1; rb2 strain. From measurements of the xanthommatin content, the rb1 mutation was suggested to enhance the expression of the rb2 gene.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D005127:Eye Color / Q000235:genetics; D005260:Female; D005838:Genotype; D006793:Houseflies / Q000201:enzymology* / Q000235:genetics / Q000254:growth & development; D050601:Kynurenine 3-Monooxygenase; D007814:Larva / Q000201:enzymology; D008297:Male; D006899:Mixed Function Oxygenases / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D010078:Oxazines / Q000032:analysis; D010641:Phenotype; D010860:Pigments, Biological; D011679:Pupa / Q000378:metabolism; D013696:Temperature; D014966:Xanthenes
chemical_list: D000596:Amino Acids; D010078:Oxazines; D010860:Pigments, Biological; D014966:Xanthenes; C002866:xanthommatin; D006899:Mixed Function Oxygenases; D050601:Kynurenine 3-Monooxygenase