Serotoninergic control of MSH secretion in the eel. Ultrastructural study after 5-hydroxytryptophan treatment.
Injection of 5-HTP induces a melanodisperson ; MSH cells are markedly stimulated :hormone synthesis (development of Golgi area and endoplasmic reticulum) and release (reduction of secretory granules) are observed. This stimulatory serotoninergic pathway seems antagonistic to the dopaminergic system that inhibits MSH secretion in the eel.
D006916:5-Hydroxytryptophan / Q000494:pharmacology*; D000818:Animals; D004524:Eels / Q000378:metabolism*; D009074:Melanocyte-Stimulating Hormones / Q000378:metabolism*; D008854:Microscopy, Electron; D010903:Pituitary Gland, Anterior / Q000648:ultrastructure
D009074:Melanocyte-Stimulating Hormones; D006916:5-Hydroxytryptophan