title: Phenothiazine-induced ventricular tachycardia following acute overdose.
abstract: The chronic use of phenothiazine is known to result in ventricular arrhythmias in certain patients. The occurrence of cardiac abnormalities following acute phenothiazine overdose is less well documented. Phenothiazine-induced ventricular tachycardia, when it occurs in the overdose situation, may be refractory to conventional antiarrhythmic drugs. We present a case in which the usual therapy was unsuccessful. Only after a transvenous pacemaker was inserted was the patient's condition reversed.
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D004599:Electric Stimulation Therapy; D004562:Electrocardiography; D005260:Female; D006801:Humans; D010138:Pacemaker, Artificial; D010640:Phenothiazines / Q000506:poisoning*; D013406:Suicide, Attempted; D013610:Tachycardia / Q000139:chemically induced* / Q000628:therapy
chemical_list: D000889:Anti-Arrhythmia Agents; D010640:Phenothiazines