Group B streptococcal colonization in a newborn nursery: effects of iodophor and triple dye cord care.
Control of nosocomial group B streptococcal (GBS) colonization of newborn infants was attempted in a four-cycle study alternately employing single applications of povidone-iodine (iodophor) and triple dye to the umbilical cord stump and periumbilical area. GBS colonization rates were 49% and 34% following iodophor cord care (cycles II and III) and 11% and 50% following triple dye cord care (cycles II and IV). The apparent significant reduction of GBS colonization during triple dye cycle II could not be reproduced in a subsequent follow-up culture survey and remains unexplained.
D004396:Coloring Agents / Q000494:pharmacology*; D003428:Cross Infection / Q000517:prevention & control; D005840:Gentian Violet / Q000494:pharmacology; D006801:Humans; D007224:Infant Care; D007231:Infant, Newborn; D007455:Iodine / Q000494:pharmacology*; D007466:Iodophors / Q000494:pharmacology*; D009725:Nurseries, Hospital; D011370:Proflavine / Q000494:pharmacology; D013292:Streptococcus agalactiae / Q000187:drug effects*; D014470:Umbilical Cord / Q000187:drug effects / Q000382:microbiology*
D004396:Coloring Agents; D007466:Iodophors; D007455:Iodine; D011370:Proflavine; D005840:Gentian Violet