Complement and Fc receptors on cord blood and adult neutrophils.
The percentage of neutrophils forming erythrocyte-antibody-complement complex (EAC) and with erythrocyte-antibody complex (EAG) was determined for 30 normal newborns and 10 normal adults. The cord values ranged from 84-100% EAC binding cells with a mean of 95%. The adult values ranged from 89-100% EAG binding cells with a mean of 96% rosetted neutrophils. The mean percentage of EAG binding cells in the cord samples was 81%, whereas in the seven adult samples the mean was 87%.
D000328:Adult; D000917:Antibody Formation; D001665:Binding Sites; D002462:Cell Membrane / Q000276:immunology; D003176:Complement C3 / Q000378:metabolism*; D003165:Complement System Proteins / Q000378:metabolism*; D004912:Erythrocytes / Q000276:immunology; D005312:Fetal Blood / Q000276:immunology*; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000378:metabolism*; D007158:Immunologic Techniques; D007231:Infant, Newborn; D009504:Neutrophils / Q000276:immunology*; D011947:Receptors, Antigen, B-Cell / Q000378:metabolism*
D003176:Complement C3; D007141:Immunoglobulin Fc Fragments; D011947:Receptors, Antigen, B-Cell; D003165:Complement System Proteins