title: Correlation between the rosette test with neuraminidase-treated sheep red blood cells and acid phosphatase activity in lymphocytes from patients with lymphoproliferative disease.
abstract: In 14 adult patients suffering from lymphoproliferative diseases, the relation between numbers of lymphocytes determined by the rosette test (nSE) with neuraminidase-treated sheep red blood cells and numbers of lymphocytes giving a positive reaction for acid phosphatase was determined. Statistical analysis of multiple test results in the patients (n = 38) showed highly positive correlation between the two markers. A similar positive correlation in the course of cytostatic treatment was observed in selected patients with type T and B cell lymphoma. The results indicate that determination of acid phosphatase activity can serve as an additional marker of T lymphocytes in groups of patients with lymphoproliferative disease.
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D006801:Humans; D008198:Lymph Nodes / Q000276:immunology; D008223:Lymphoma / Q000201:enzymology / Q000276:immunology; D008228:Lymphoma, Non-Hodgkin / Q000201:enzymology / Q000276:immunology; D008232:Lymphoproliferative Disorders / Q000201:enzymology / Q000276:immunology*; D009439:Neuraminidase / Q000378:metabolism; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000201:enzymology / Q000276:immunology*
chemical_list: D000135:Acid Phosphatase; D009439:Neuraminidase