title: Implication of protein aromatic amino acids in concanavalin A-carbohydrate interactions. A radiolytic study.
abstract: Pulse radiolysis and 60Co gamma-radiolysis have been used to study the effects of ionizing radiation on the glycogen-precipitating activity of the protein concanavalin A. Both eaq- and OH. react extremely rapidly with the protein and contribute to the observed loss of concanavalin A activity. Evidence is also presented that (Br)2-. and (SCN)2-. react with with tyrosine and tryptophan residues in concanavalin A, which is also accompanied by loss of glycogen precipitation activity.
mesh_terms: D003037:Cobalt Radioisotopes; D003208:Concanavalin A / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006003:Glycogen; D011675:Pulse Radiolysis; D011952:Receptors, Concanavalin A / Q000528:radiation effects; D014364:Tryptophan; D014443:Tyrosine
chemical_list: D003037:Cobalt Radioisotopes; D011952:Receptors, Concanavalin A; D003208:Concanavalin A; D014443:Tyrosine; D014364:Tryptophan; D006003:Glycogen