Antimicrobial prophylaxis of contaminated tissues containing suture implants.
Neomycin sulfate was the only antibiotic tested that significantly reduced the incidence of infections around suture implant sites. The therapeutic efficacy of this antibiotic was related to the chemical and physical configuration of the sutures.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004927:Escherichia coli Infections / Q000517:prevention & control; D051379:Mice; D009355:Neomycin / Q000627:therapeutic use; D013203:Staphylococcal Infections / Q000517:prevention & control; D013211:Staphylococcus aureus; D013530:Surgical Wound Infection / Q000517:prevention & control*; D013537:Sutures
D000900:Anti-Bacterial Agents; D009355:Neomycin