Punctiform and polychromatic pre-Descemet's dominant corneal dystrophy.
A new type of pre-Descemet's corneal dystrophy is described. The opacities are punctiform, polychromatic, of uniform size, and evenly distributed over the whole cornea. The diagnosis is made only by slit lamp because there is no visual impairment. The disease is hereditary and follows the autosomal mode of inheritance with a high percentage of penetrance, expressivity, and specificity in 4 successive generations, in which 8 affected members were observed among a total of 46.
D000328:Adult; D000368:Aged; D002675:Child, Preschool; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D003315:Cornea / Q000473:pathology; D003317:Corneal Dystrophies, Hereditary / Q000145:classification / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree