[The action of vitamin D2 and of 25-hydroxy-cholecalciferol on calcemia and urinary calcium excretion in the alcoholic cirrhotic (author's transl)].
In 2 similar groups of alcoholic cirrhotics with definite hepatic failure, the results of the oral administration of 25-hydroxycholecalciferol and of vitamin d2 on calcemia and urinary calcium excretion were studied. 25-hydroxycholecalciferol definitely increases calcemia and urinary calcium excretion, this action being superior to that of vitamin D2. This action which occurs, at least in part, by an increase in intestinal calcium absorption, deomonstrated the true nature of the "hepatic block" of vitamin D2 in alcoholic cirrhosis and the value of the administration of 25-hydroxycholecalciferol.
D002118:Calcium / Q000378:metabolism*; D004872:Ergocalciferols / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use*; D007408:Intestinal Absorption / Q000187:drug effects; D008104:Liver Cirrhosis, Alcoholic / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
D004872:Ergocalciferols; D006887:Hydroxycholecalciferols; D002118:Calcium
Action de la vitamine D2 et du 25-hydroxycholécalciférol sur la calcémie et la calciurie du cirrhotique alcoolique.