A study of the photoinduced mutagenicity of methylene blue.
Illumination of Salmonella typhimurium strains in the presence of methylene blue resulted in the production of mutations of the base-substitution type. This photodynamic effect mediated by the dye was separable from the genetic event seen when bacteria are illuminated in the absence of added photosensitizers.
D008027:Light; D008751:Methylene Blue / Q000494:pharmacology*; D009153:Mutagens; D009154:Mutation; D010777:Photochemistry; D012486:Salmonella typhimurium / Q000528:radiation effects
D009153:Mutagens; D008751:Methylene Blue