Active E rosette formation by human lymphoblasts.
The percentage of active and total E rosettes for lymphocytes cultured for 72 h both with and without phytohaemagglutinin (PHA) was evaluated in 20 normal subjects. A clear increase in the formation of active E rosettes by PHA-stimulated lymphocytes was demonstrated with respect to unstimulated lymphocytes. Our data gives further proof that the active E rosettes constitute a specific subpopulation of lymphocytes which represent functionally active T cells in the blood.
D000328:Adult; D006801:Humans; D008213:Lymphocyte Activation; D008875:Middle Aged; D010835:Phytohemagglutinins / Q000494:pharmacology; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
D010835:Phytohemagglutinins