title: [Complications of antithrombotic prophylaxis with acetylsalicylic acid (ASS) in polycythemia (author's transl)].
abstract: Eight patients with polycythemia whose main complaints resulted from vascular complications were prophylactically treated with ASS. 4 patients tolerated the treatment without any side effects, 4 patients had an acute upper gastrointestinal hemorrhage, which was fatal in 2 cases. Correlations between the thrombohemorrhagical syndrome in polycythemia on one hand and the side effects of ASS on the other hand are discussed. As a result of this antithrombotic prophylaxis with ASS is not indicated in polycythemia even in predominance of vascular complications and absence of bleeding tendency. In life-threatening situations antithrombotic therapy with heparine should be preferred.
mesh_terms: D000368:Aged; D001241:Aspirin / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced*; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011087:Polycythemia Vera / Q000150:complications*; D013927:Thrombosis / Q000517:prevention & control*
chemical_list: D006493:Heparin; D001241:Aspirin
vernacular_title: Komplikationen der Thromboseprophylaxe mit Acetylsalicylsäure bei Polycythaemia vera.