[Rosette formation test for evaluating the immunological state of serum hepatitis patients].
The number of T-lymphocytes was determined by the method of spontaneous rosette formation according to Bach et al., and of B-lymphocytes by the method of complementary rosette formation of Mendes et al. in 57 patients with serum hepatitis whose diagnosis had been confirmed by laboratory studies (HBsAg+) in the course of the disease. A decrease in the absolute and relative amount of T-lymphocytes was observed at the peak of the disease and was particularly marked in patients with severe disease. The values of B-lymphocytes did not change significantly in most patients throughout the disease but lower values of both relative and absolute numbers were observed in severe and fulminant forms. The amount of O-lymphocytes increased at the peak of the disease, particularly in severely ill patients. These results may be used as an additional test in the evaluation of the severity of a patient's condition.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology; D006509:Hepatitis B / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007958:Leukocyte Count; D008875:Middle Aged; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology
Test rozetkoobrazovaniia dlia otsenki immunologicheskogo statusa bol'nykh syvorotochnym gepatitom.