[Current aspects of human heart transplantation. II. Postoperative surveillance and results].
The cardiac transplantation program of the Pitié-Salpêtrière Hospital has, since October 1973, involved 17 transplants with 15 recipients. Seven patients are alive. Real progress has been achieved in all areas: --selection of the recipient, now more strict is dependent upon precise criteria; --choice of the donor should take into account the best possible tissue and haemodynamic compatibility; --immuno-depressive therapy involves the combination of corticosteroids, azathioprine, antilymphocytic globulins and heparin. It is varied as necessary in relation to episodes of rejection; --the diagnosis of rejection is based upon clinical, radiological and electrical criteria, but also upon new and precise haemodynamic and biological criteria; --long term control is facilitated by regular telephone transmission of the electrocardiogram. The prognosis remains reserved but with socio-professional rehabilitation to help in overcoming the initial slight degree of "hospitalism", the sensation of a new life is such that cardiac transplantation represents an acceptable solution in the treatment of certain cardiac diseases.
D001424:Bacterial Infections / Q000209:etiology; D002302:Cardiac Output; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D004562:Electrocardiography; D005500:Follow-Up Studies; D006084:Graft Rejection; D006321:Heart / Q000000981:diagnostic imaging; D006326:Heart Auscultation; D016027:Heart Transplantation; D006439:Hemodynamics; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007545:Isoproterenol / Q000008:administration & dosage; D010490:Pericardial Effusion / Q000209:etiology; D011020:Pneumonia, Pneumocystis / Q000209:etiology; D011182:Postoperative Care; D011183:Postoperative Complications; D011859:Radiography; D012046:Rehabilitation; D013689:Telephone; D014184:Transplantation, Homologous; D014937:Work
D007166:Immunosuppressive Agents; D007545:Isoproterenol
Aspects actuels de la transplantation cardiaque humaine. II. Surveillance post-opératoire et résultats