Correlation between the rosette test with neuraminidase-treated sheep red blood cells and acid phosphatase activity in lymphocytes from patients with lymphoproliferative disease.
In 14 adult patients suffering from lymphoproliferative diseases, the relation between numbers of lymphocytes determined by the rosette test (nSE) with neuraminidase-treated sheep red blood cells and numbers of lymphocytes giving a positive reaction for acid phosphatase was determined. Statistical analysis of multiple test results in the patients (n = 38) showed highly positive correlation between the two markers. A similar positive correlation in the course of cytostatic treatment was observed in selected patients with type T and B cell lymphoma. The results indicate that determination of acid phosphatase activity can serve as an additional marker of T lymphocytes in groups of patients with lymphoproliferative disease.
D000135:Acid Phosphatase / Q000378:metabolism*; D006801:Humans; D008198:Lymph Nodes / Q000276:immunology; D008223:Lymphoma / Q000201:enzymology / Q000276:immunology; D008228:Lymphoma, Non-Hodgkin / Q000201:enzymology / Q000276:immunology; D008232:Lymphoproliferative Disorders / Q000201:enzymology / Q000276:immunology*; D009439:Neuraminidase / Q000378:metabolism; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000201:enzymology / Q000276:immunology*
D000135:Acid Phosphatase; D009439:Neuraminidase