[Therapy of alcoholism. The use of thiamine, ATP and magnesium and the control of clomethiazole sympathetic blockade (author's transl)].
Substitution therapy with thiamine, ATP and magnesium which, just like that with clomethiazole has a parasympathomimetic action, is based on the principle of suppression of the sympathetic system. If these patients are no longer capable for any reason of continuing to take the endogenous substances (thiamine, ATP and magnesium) by mouth, the treatment is continued with clomethiazole an an infusion. But since the intravenous administration of clomethiazole is not seldom accompanied by a parasympathetic coma with respiratory and cardiac depression and miosis, treatment of a sympathetic blockade with dextrose solution containing salt is proposed.
D000255:Adenosine Triphosphate / Q000627:therapeutic use*; D000328:Adult; D000437:Alcoholism / Q000188:drug therapy*; D002719:Chlormethiazole / Q000009:adverse effects / Q000037:antagonists & inhibitors / Q000627:therapeutic use*; D003128:Coma / Q000139:chemically induced / Q000188:drug therapy; D003911:Dextrans / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008274:Magnesium / Q000627:therapeutic use*; D008297:Male; D013564:Sympathetic Nervous System / Q000187:drug effects; D013831:Thiamine / Q000627:therapeutic use*
D003911:Dextrans; D002719:Chlormethiazole; D000255:Adenosine Triphosphate; D008274:Magnesium; D013831:Thiamine
Therapie der Alkoholkrankheit. Anwendung von Thiamin, ATP und Magnesium sowie Bekämpfung einer durch Chlormethiazol entstandenen Sympathikus-Blockade.