Suppression of intrinsic B-cell function in Dengue-infected mice.
Mice infected with Dengue virus show a depressed immune response to lipopolysaccharide (LPS), a helper T-cell-independent antigen, when LPS was administered on day 0, 6 and 12 post infection. Mice injected with inactivated virus failed to show immunosuppression.
D000818:Animals; D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology*; D003716:Dengue Virus / Q000276:immunology*; D007165:Immunosuppression Therapy; D007700:Kinetics; D008070:Lipopolysaccharides / Q000276:immunology; D051379:Mice
D008070:Lipopolysaccharides