title: Low molecular weight intracellular iron transport compounds.
abstract: Evidence is presented for the existence of an intracellular pool of low molecular weight iron compounds which acts as an intermediate between extracellular iron and a wide variety of intracellular processes. It is in equilibrium with storage iron and iron enzymes and is of major importance in iron toxicity and chelation therapy.
mesh_terms: D001692:Biological Transport; D002460:Cell Line; D003600:Cytosol / Q000032:analysis; D003676:Deferoxamine / Q000494:pharmacology; D004847:Epithelial Cells; D004848:Epithelium / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism*; D005293:Ferritins / Q000096:biosynthesis; D006418:Heme / Q000096:biosynthesis; D006801:Humans; D007413:Intestinal Mucosa / Q000166:cytology; D007501:Iron / Q000097:blood* / Q000378:metabolism / Q000502:physiology; D007502:Iron Chelating Agents / Q000378:metabolism; D007700:Kinetics; D008928:Mitochondria / Q000378:metabolism; D010586:Phagocytes / Q000378:metabolism
chemical_list: D007502:Iron Chelating Agents; D006418:Heme; D005293:Ferritins; D007501:Iron; D003676:Deferoxamine