title: An investigation into the effect on cigarette smoking of a new anti-smoking chewing gum.
abstract: A preparation claimed to help patients to break the habit of smoking has recently been introduced. Material released in the mouth from a chewing gum causes an unpleasant taste when tobacco smoke is inhaled. This claim has been investigated in a double-blind trial on sixty subjects, thirty of whom took the active chewing gum and thirty the placebo chewing gum. The subjects each used one piece of chewing gum four times a day over a period of two weeks. This investigation clearly indicates that the active chewing gum is effective as an anti-smoking preparation, when used over a period of two weeks and the effect is still demonstrable one month later, although to a lesser extent.
mesh_terms: D000085:Acetates / Q000627:therapeutic use; D000328:Adult; D000643:Ammonium Chloride / Q000627:therapeutic use; D002638:Chewing Gum; D002986:Clinical Trials as Topic; D004338:Drug Combinations; D006801:Humans; D010919:Placebos; D012834:Silver / Q000627:therapeutic use; D000074606:Smoking Prevention; D013835:Thiamine Pyrophosphate / Q000627:therapeutic use
chemical_list: D000085:Acetates; D002638:Chewing Gum; D004338:Drug Combinations; D010919:Placebos; D000643:Ammonium Chloride; D012834:Silver; D013835:Thiamine Pyrophosphate