Labelling of lymphocytes with various radiosotopes for in vivo tracer studies; a review.
Several methods are available for labelling lymphoid cells with radioactive markers e.g. 3H, 14C, 125I, 131I, 35S, 75Se, based on general metabolic processes, involving DNA, RNA and protein synthesis in these cells. Together with methods for labelling lymphoid cells with 51Cr and 99mTc, radioisotopes which are captured in cells but not incorporated in its metabolites, these will be reviewed in the present paper. Attention will be given to possible applications of the use of radiosotope labels.
D000596:Amino Acids / Q000378:metabolism; D002250:Carbon Radioisotopes; D002860:Chromium Radioisotopes; D004247:DNA / Q000096:biosynthesis; D003841:Deoxycytidine / Q000378:metabolism; D007065:Idoxuridine / Q000378:metabolism; D007553:Isotope Labeling / Q000379:methods*; D008214:Lymphocytes / Q000276:immunology / Q000528:radiation effects; D014176:Protein Biosynthesis; D012313:RNA / Q000096:biosynthesis; D011868:Radioisotopes / Q000009:adverse effects; D013667:Technetium; D013936:Thymidine / Q000378:metabolism; D014316:Tritium; D014529:Uridine / Q000378:metabolism
D000596:Amino Acids; D002250:Carbon Radioisotopes; D002860:Chromium Radioisotopes; D011868:Radioisotopes; D003841:Deoxycytidine; D014316:Tritium; D012313:RNA; D013667:Technetium; D004247:DNA; D007065:Idoxuridine; D013936:Thymidine; D014529:Uridine