Mutual relationship between total and active  T lymphocytes in patients with malignant tumors.
The values of B lymphocytes and of active and total T lymphocytes have been followed in 104 patients with malignant diseases and 35 controls of corresponding age, using the rosette tests with sheep erythrocytes. A statistical analysis of the changes of total and active T lymphocytes in three selected groups of the malignant disorder revealed the decline in total T lymphocytes to be parallel to that in active T lymphocytes. Therefore, a follow-up of the immunocompetence of oncological patients with the criterion determination of thymus-dependent lymphocyte population by the classical method of rosette formation was found to be equally informative in the three groups of patients studied here, as an evolution of active T lymphocytes in the active rosette test.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D001943:Breast Neoplasms / Q000276:immunology; D002648:Child; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006801:Humans; D007938:Leukemia / Q000276:immunology; D008223:Lymphoma / Q000276:immunology; D008297:Male; D008545:Melanoma / Q000276:immunology; D008875:Middle Aged; D009369:Neoplasms / Q000276:immunology*; D012397:Rosette Formation; D012756:Sheep; D013601:T-Lymphocytes / Q000276:immunology*; D013736:Testicular Neoplasms / Q000276:immunology