title: [Stenosis of the aqueduct of Sylvius and their endocrine manifestations (author's transl)].
abstract: In a 14-year-old boy, neurological signs (fall in visual acuity, signs of raised intracranial pressure) led to a diagnosis of stenosis of the aqueduct of Sylvius. Cure was obtained by insertion of a ventriculo-cardiac bypass (Holter's valve). Endocrine signs (delayed growth, excessweight, loss of circadian variations in cortisol levels) regressed in a few months after the operation. Amongst endocrine manifestations of stenosis of the aqueduct, delayed growth and disturbances in gonadal function are the most common, together with obesity. They usually regress after neurosurgical treatment.
mesh_terms: D000293:Adolescent; D002524:Cerebellar Ataxia / Q000209:etiology; D002535:Cerebral Aqueduct; D014695:Cerebral Ventriculography; D002557:Cerebrospinal Fluid Shunts; D003251:Constriction, Pathologic / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D004700:Endocrine System Diseases / Q000209:etiology*; D005260:Female; D005831:Genital Diseases, Female / Q000209:etiology; D005832:Genital Diseases, Male / Q000209:etiology; D006130:Growth Disorders / Q000209:etiology; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D006854:Hydrocortisone / Q000097:blood; D002542:Intracranial Embolism and Thrombosis; D008297:Male; D009765:Obesity / Q000209:etiology; D011011:Pneumoencephalography
chemical_list: D006854:Hydrocortisone
vernacular_title: Les sténoses de l'aqueduc de Sylvius et leurs manifestations endocriniennes.