[About employing platelets to determine enterotoxigenic activity of E. coli and others enterobacteria. Preliminary approach (author's transl)].
After an introduction concerning to the assays employed in vitro and in vivo to determine enterotoxigenic activity of E. coli the A. suggest a new in vitro model as a preliminary approach based upon the influence of LT enterotoxin of E. coli on platelet aggregation (inhibitory effect) as expression of stimulation of adenylatecyclase activity evoked by this fraction and eventually by other choleralyke fractions released from enterobacteria.
D000818:Animals; D004755:Enterobacteriaceae / Q000472:pathogenicity*; D004768:Enterotoxins; D004926:Escherichia coli / Q000472:pathogenicity*; D006801:Humans; D010974:Platelet Aggregation
D004768:Enterotoxins
Approccio preliminare sul possibile impiego delle piastrine come sistema cellulare utilizzabile per la verifica della enteropatogenicità di "Escherichia coli" e di altri enterobatteri.