Hodgkin's disease - a 'B' neoplasm?
Lymph node tissue from 2 patients with Hodgkin's disease was studied by light microscopy using the immunoperoxidase technique with a panel of monospecific antisera. Hodgkin's mononuclear and Reed-Sternberg cells were shown to exhibit features characteristic of B cells. The possibility that Hodgkin's disease is a B-cell neoplasm is discussed.
D001402:B-Lymphocytes / Q000473:pathology; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D013601:T-Lymphocytes / Q000473:pathology