Experimental results of the use of flavofosfolipol in dairy cattle.
In a field trial carried out on a farm with about 100 dairy cows, half of the animals were treated orally with 45 mg flavofosfolipol per animal daily for 370 days, while the other half were untreated controls. The administration of the flavofosfolipol did not produce any residues in the milk. Body functions and fertility were not affected. Milk production was increased, although not with statistical significance. The qualitative characteristics of the milk and its cheese-making properties were normal. The casein content was increased by 6.58% over that of the controls, and thus was statistically significant. There was a statistically significant decrease in the mean cell content of the milk. The high negative correlation between the casein level and the cell content of the milk suggests that an improvement in the function of the mammary parenchyma could be responsible for the higher casein content. This improvement in function could also be due to a favourable effect of the antibiotic, still to be clarified, on the ruminal microflora. In economic terms the use of flavofosfolipol in dairy cattle seems to be of considerable interest.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001455:Bambermycins / Q000008:administration & dosage / Q000494:pharmacology* / Q000633:toxicity; D002118:Calcium / Q000032:analysis; D002364:Caseins / Q000032:analysis; D002417:Cattle / Q000502:physiology*; D005260:Female; D005298:Fertility / Q000187:drug effects; D007774:Lactation / Q000187:drug effects; D008055:Lipids / Q000032:analysis; D008321:Mammary Glands, Animal / Q000187:drug effects; D008892:Milk / Q000032:analysis* / Q000166:cytology; D008894:Milk Proteins / Q000032:analysis; D011247:Pregnancy; D013997:Time Factors
D000900:Anti-Bacterial Agents; D002364:Caseins; D008055:Lipids; D008894:Milk Proteins; D001455:Bambermycins; D002118:Calcium