Separation of epidermis from dermis with sodium thiocyanate.
After human skin is treated with 2 N sodium thiocyanate, epidermis is easily separated from dermis. The level of cleavage occurs at the lamina lucida of the basement membrane zone. Bullous pemphigoid antigen remains attached to the epidermis.
D006652:Histological Techniques; D006801:Humans; D012867:Skin / Q000187:drug effects / Q000648:ultrastructure; D013861:Thiocyanates / Q000494:pharmacology
D013861:Thiocyanates