A new rat lymphocyte surface marker: characterization and separation of cells with receptors for Helix pomatia hemagglutinin.
Thirty-two percent of neuraminidase-treated DA rat spleen lymphocytes and 48% of lymph node lymphocytes possess receptors for Helix pomatia hemagglutinin (HP). Moreover, these HP-receptor-bearing cells can be separated from B cells by affinity chromatography on HP-Sepharose columns. The virtual absence of immunoglobulin (Ig) receptors and the close correlation with reported T-cell content of these lymphoid tissues suggest that HP-receptor lymphocytes are probably T cells and that HP may provide a convenient marker, for both the identification and the purification of rat T lymphocytes.
D000373:Agglutinins; D000818:Animals; D000918:Antibody Specificity; D001666:Binding Sites, Antibody; D002458:Cell Fractionation; D002462:Cell Membrane / Q000276:immunology; D002469:Cell Separation; D005455:Fluorescent Antibody Technique; D006372:Helix, Snails; D006388:Hemagglutinins; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D051381:Rats
D000373:Agglutinins; D006388:Hemagglutinins