[Characteristics of the functional activity of human blood neutrophils using the nitroblue tetrazolium reduction test].
A study was made of the test of restoration of the nitroblue tetrazolium (NBT) by the intact blood neutrophils and the neutrophils stimulated with various endotoxin doses of Gram-negative bacteria in 70 healthy persons. A high sensitivity of the test with the NBT for the quantitative assessment of the neutrophil response under conditions stimulating the phagocytic activity was demonstrated. A functional nonhomogeneity of the neutrophil population, the most distinct with the minimal stimulating action, was noted.
D000328:Adult; D004731:Endotoxins / Q000494:pharmacology*; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000378:metabolism*; D009580:Nitroblue Tetrazolium / Q000378:metabolism*; D010084:Oxidation-Reduction; D012706:Serratia marcescens / Q000032:analysis; D013778:Tetrazolium Salts / Q000378:metabolism*
D004731:Endotoxins; D013778:Tetrazolium Salts; D009580:Nitroblue Tetrazolium
Kharakteristika funktsional'noĭ aktivnosti neĭtrofilov krov cheloveka s pomoshch'iu reaktsii vosstanovleniia nitrosinego tetrazoliia.