title: RNA-ligant interactions. (I) Magnesium binding sites in yeast tRNAPhe.
abstract: X-ray crystallagraphic studies studies indicate that there are at least four site-specifically bound hydrated Mg2+ ions, [Mg(H2O)n]2+, in yeast tRNAPhe. The size and the octahedral coordination geometry, rather than the charge, of [Mg(H2O)N]2+ appear to be the primary reasons for the specificity of magnesium ions in site-binding and in the stabilization of the tertiary structure of tRNA.
mesh_terms: D001665:Binding Sites; D055598:Chemical Phenomena; D002621:Chemistry; D008024:Ligands; D008274:Magnesium; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D010649:Phenylalanine; D012343:RNA, Transfer; D012441:Saccharomyces cerevisiae; D014961:X-Ray Diffraction
chemical_list: D008024:Ligands; D010649:Phenylalanine; D012343:RNA, Transfer; D008274:Magnesium