Delayed foreign-body tumorigenesis in mice infected with lactate dehydrogenase-elevating virus: Brief communication.
Female and male CBA/H mice were infected with lactate dehydrogenase virus (LDV). Two weeks later, these mice and noninfected controls received double sc implants of unplasticized vinyl chloride-vinyl acetate copolymer films (0.2 X 15 X 22 mm). Foreign-body (FB) tumorigenesis was delayed in LDV-infected females and males by 2 months. This result could not be explained by an effect of LDV on cellular immunity, inasmuch as cellular immunity does not influence the course of FB tumorigenesis.
D000818:Animals; D005260:Female; D005549:Foreign-Body Reaction / Q000150:complications*; D007772:Lactate dehydrogenase-elevating virus / Q000276:immunology*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D011143:Polyvinyl Chloride; D012513:Sarcoma, Experimental / Q000209:etiology / Q000276:immunology*; D014753:Vinyl Compounds; D014777:Virus Diseases / Q000276:immunology
D014753:Vinyl Compounds; D011143:Polyvinyl Chloride