Mitogenic effects of murine serum and fibroblast growth factor on EGF nonproliferative variants of 3T3.
The enhanced ability of murine serum to support growth of 3T3 cells, when compared with fetal calf serum, is also evident on variants of 3T3 cells lacking the ability to bind epidermal growth factor (EGF). Variant 3T3 cell lines unable to bind EGF also retain a mitogenic response to fibroblast growth factor.
D000818:Animals; D002417:Cattle; D002460:Cell Line; D004815:Epidermal Growth Factor / Q000378:metabolism*; D005312:Fetal Blood; D005346:Fibroblast Growth Factors; D008297:Male; D051379:Mice / Q000097:blood*; D008934:Mitogens / Q000494:pharmacology; D009154:Mutation; D010455:Peptides / Q000378:metabolism* / Q000494:pharmacology*
D008934:Mitogens; D010455:Peptides; D005346:Fibroblast Growth Factors; D004815:Epidermal Growth Factor