title: The value of calcium dobesilate in the treatment of diabetic retinopathy. A controlled clinical trial.
abstract: The effect of calcium dobesilate on capillary resistance and background retinopathy was compared with placebo in a double-blind cross-over trial on 18 diabetics. Each treatment lasted 8 months. The trial produced no evidence in favour of a significant beneficial effect of calcium dobesilate on the capillary resistance in diabetics or on the course of the diabetic retinopathy.
mesh_terms: D000328:Adult; D000368:Aged; D001557:Benzenesulfonates / Q000627:therapeutic use*; D002123:Calcium Dobesilate / Q000627:therapeutic use*; D002200:Capillary Resistance / Q000187:drug effects; D002986:Clinical Trials as Topic; D003930:Diabetic Retinopathy / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography
chemical_list: D001557:Benzenesulfonates; D002123:Calcium Dobesilate