Platelets and glomerulonephritis.
There is evidence derived from both experimental studies and from observation of human nephritis that platelets are important in the glomerular injury of chronic soluble-complex disease. It is not yet clear if platelets are involved in the events initiating endothelial damage, in perpetuating and amplifying injury, or both. Antiplatelet agents appear to have a role in the treatment of chronic forms of glomerulonephritis; but more knowledge of platelet involvement in nephritis and more readily available tests for platelet involvement are necessary before this suggestion can be tested intelligently.
D001792:Blood Platelets / Q000502:physiology*; D005921:Glomerulonephritis / Q000097:blood / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D010974:Platelet Aggregation
D007074:Immunoglobulin G; D007075:Immunoglobulin M