title: The response of ophthalmic arterial pressure to topically applied clonidine.
abstract: The effect of topically applied clonidine on aphthalmic arterial pressure was tested in three groups of open-angle glaucoma patients. In this test, 0.125% clonidine eye drops did not cause a statistically significant change in ophthalmic arterial pressure, but 0.25% and 0.5% clonidine caused a statistically significant, dose-dependent decrease in the diastolic and the systolic arterial pressure in the orbit. The clinical relevance of the results is discussed.
mesh_terms: D001794:Blood Pressure / Q000187:drug effects*; D002908:Chronic Disease; D003000:Clonidine / Q000008:administration & dosage / Q000494:pharmacology*; D005901:Glaucoma / Q000503:physiopathology; D006801:Humans; D009880:Ophthalmic Artery
chemical_list: D003000:Clonidine