Coexistence of haemophilia A and von Willebrand's disease in the same kindred.
A clinical and laboratory investigation of a kindred in which haemophilia A and autosomal recessive von Willebrand's disease (VWD) were concomitantly present is described. 3 male patients were shown to be hemizygotes for moderate haemophilia A, one female appeared to be haemophilia A carrier and 3 males showed laboratory findings consistent with heterozygosity for autosomal recessive VWD. In one woman, the pedigree and laboratory findings suggest the possibility of double heterozygosity.
D001779:Blood Coagulation Factors; D001789:Blood Group Antigens; D005260:Female; D006467:Hemophilia A / Q000150:complications / Q000235:genetics*; D006801:Humans; D008297:Male; D010375:Pedigree; D014842:von Willebrand Diseases / Q000150:complications / Q000235:genetics*
D001779:Blood Coagulation Factors; D001789:Blood Group Antigens