Mutagenicity of dieldrin in the Salmonella-microsome test.
Dieldrin was assayed in vitro for its mutagenic activity in several strains of S. typhimurium with and without Aroclor 1254 treated mouse liver homogenate (S-9M). The mutagenicity of the insecticide was expressed maximally in all strains in the presence of liver S-9M and less so in three strains without liver microsomes.
D000818:Animals; D004026:Dieldrin / Q000494:pharmacology*; D005821:Genetic Techniques; D006639:Histidine / Q000378:metabolism; D051379:Mice; D008862:Microsomes, Liver / Q000378:metabolism; D009153:Mutagens; D010641:Phenotype; D012486:Salmonella typhimurium / Q000378:metabolism
D009153:Mutagens; D006639:Histidine; D004026:Dieldrin