Interrelationships of mycotoxins with nutrition.
Mycotoxins interact with lipid, protein, carbohydrate, and vitamin nutrition. Diets high in lipid have a mortality-sparing effect against aflatoxicosis and, if high in unsaturated fatty acids, a growth-sparing effect. Aflatoxicosis causes a lipid malabsorption syndrome coupled with decreased digestive enzymes and bile salt excretion, a decreased synthesis of fatty acids, and impaired transport. Deficiencies of vitamins A, D, or riboflavin make animals more sensitive to aflatoxin while a thiamin deficiency has the opposite effect. Interaction with vitamins E and K has not been clearly demonstrated as yet. Mycotoxins increase the protein requirements of animals and apparently alter the enzymes that regulate glycogen catabolism and neogenesis.
D000818:Animals; D050260:Carbohydrate Metabolism; D004040:Dietary Carbohydrates; D004044:Dietary Proteins; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D009183:Mycotoxins / Q000378:metabolism* / Q000494:pharmacology; D009747:Nutritional Physiological Phenomena; D011506:Proteins / Q000378:metabolism; D012256:Riboflavin / Q000378:metabolism; D013045:Species Specificity; D013831:Thiamine / Q000378:metabolism; D014801:Vitamin A / Q000378:metabolism; D014807:Vitamin D / Q000378:metabolism; D014810:Vitamin E / Q000378:metabolism; D014812:Vitamin K / Q000378:metabolism
D004040:Dietary Carbohydrates; D004044:Dietary Proteins; D009183:Mycotoxins; D011506:Proteins; D014801:Vitamin A; D014812:Vitamin K; D014807:Vitamin D; D014810:Vitamin E; D012256:Riboflavin; D013831:Thiamine