Bactericidal effects of combinations of ampicillin with anti-R-plasmid compounds on Salmonella typhimurium R1+.
Salmonella typhimurium R1(+), resistant to 2,500 mug of ampicillin per ml, was rapidly killed by combinations of 60 mug of ampicillin per ml with quinacrine (4 x 10(-4) M), ethidium bromide (10(-4) M), tilorone (10(-4) M), or Nitroakridin 3582 (5 x 10(-6) M).
D000166:Acridines / Q000494:pharmacology; D000667:Ampicillin / Q000494:pharmacology*; D004338:Drug Combinations; D004996:Ethidium / Q000494:pharmacology; D011796:Quinacrine / Q000494:pharmacology; D011815:R Factors / Q000187:drug effects; D012486:Salmonella typhimurium / Q000187:drug effects*; D013994:Tilorone / Q000494:pharmacology
D000166:Acridines; D004338:Drug Combinations; D000667:Ampicillin; D004996:Ethidium; D011796:Quinacrine; D013994:Tilorone