[Induction of the synthesis of various colicins by the action of N-methyl-N'-nitro-N-nitrosoguanidine and chloramphenicol].
The effect of N-methyl-N'-nitro-N-nitrosoguanidine on colicinogenic cells is shown to result in the induction of the synthesis of colicins B1, B4, K, Ia-CA53, Ib-P9 and V3. Chloramphenicol induces the synthesis of colicins B1, B4, K, V3 and, possibly, Ib-P9. The data obtained indicate, that there is a similarity between derepression mechanisms of different colicinogenic factors.
D003086:Bacteriocin Plasmids / Q000187:drug effects; D002701:Chloramphenicol / Q000494:pharmacology*; D003087:Colicins / Q000096:biosynthesis*; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics; D008769:Methylnitronitrosoguanidine / Q000494:pharmacology*
D003087:Colicins; D008769:Methylnitronitrosoguanidine; D002701:Chloramphenicol
Induktsiia sinteza razlichnykh kolitsinov pri deĭstvii N-metil-N'-nitro-N-nitrozoguanidina i khloramfenikola.