Macular lesions in Alport's disease.
In three male patients with Alport's disease, two of them successfully treated by kidney transplantation, ophthalmoscopy revealed bilaterally densely packed whitish-yellow lesions around, and to some extent in, the macular area. These spots, superficially located in the retina, have not been previosly desribed in Alport's disease.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003638:Deafness / Q000235:genetics; D004585:Electrooculography; D004596:Electroretinography; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007223:Infant; D016030:Kidney Transplantation; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009394:Nephritis, Hereditary / Q000175:diagnosis / Q000235:genetics / Q000473:pathology*; D010375:Pedigree; D012164:Retinal Diseases / Q000175:diagnosis / Q000235:genetics / Q000473:pathology*; D014792:Visual Acuity