[Tubular involvement in glomerular diseases of the kidney (author's transl)].
An attempt is made in this study to provide an answer to the question whether glomerular diseases are accompanied by tubular disorders. The urinary lysozyme activity was determined by means of a turbidimetric assay method in 10 healthy children as controls, 10 patients with glomerulonephritis, 8 patients with Alport's syndrome (hereditary glomerulonephritis with deafness) and 12 children with idiopathic nephrotic syndrome. In most of the cases a significant increase in urinary lysozyme excretion, indicative of tubular damage, was found and this finding correlates well with the tubular morphology of the patients.
D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D005921:Glomerulonephritis / Q000652:urine; D006801:Humans; D007223:Infant; D007674:Kidney Diseases / Q000503:physiopathology*; D007678:Kidney Glomerulus / Q000503:physiopathology*; D007684:Kidney Tubules / Q000503:physiopathology*; D009113:Muramidase / Q000652:urine; D009394:Nephritis, Hereditary / Q000652:urine; D009404:Nephrotic Syndrome / Q000652:urine
D009113:Muramidase
Tubuläre Mitbeteiligung bei glomerulren Erkrankungen der Niere