title: Indoramin--an alpha adrenoreceptor antagonist for airway obstruction.
abstract: Indoramin, an alpha adrenoreceptor antagonist, was given in tablet form, in addition to regular salbutamol by aerosol, to 30 patients with airway obstruction. Indoramin produced a small increase in peak flow rate, no change in forced expiratory volume in one second and no improvement in symptoms. Troublesome unwanted effects occurred in six patients.
mesh_terms: D000328:Adult; D000368:Aged; D000402:Airway Obstruction / Q000188:drug therapy*; D000420:Albuterol / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D005260:Female; D005540:Forced Expiratory Flow Rates; D006801:Humans; D007211:Indoles / Q000627:therapeutic use*; D007217:Indoramin / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
chemical_list: D007211:Indoles; D007217:Indoramin; D000420:Albuterol