title: Binding of chloramphenicol and its acetylated derivatives to Escherichia coli ribosomal subunits.
abstract: Chloramphenicol-acetylated derivatives (1-monoacetoxy-; 3-monoacetoxy-; 1,3-diacetoxy-chloramphenicol), produced by a wild type Escherichia coli strain carrying an R factor, have been extracted and purified. None of the acetylated derivatives has been found to bind to E. coli ribosomal subunits.
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis; D002701:Chloramphenicol / Q000031:analogs & derivatives* / Q000378:metabolism*; D004926:Escherichia coli / Q000378:metabolism*; D012270:Ribosomes / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D002701:Chloramphenicol