G-cell counts in antral endoscopic biopsies by immunofluorescence.
Antral gastrin-producing cell (G-cells) were counted by an immunofluorescence technique in the antral biopsies obtained at endoscopy from 67 subjects; they included patients with duodenal ulcer, gastritis, and individuals with a normal gastric mucosa. The G-cell count was significantly lower (P less than 0.01) in patients with duodenal ulcer (142 G cells per mm2) in comparison to normal subjects (327 G cells per mm2). No statistically significant correlation was found between the G-cell number and any of the other parameters tested (pentagastrin test, basal serum gastrin and its response to a standard meal).
D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002452:Cell Count / Q000379:methods*; D004381:Duodenal Ulcer / Q000473:pathology*; D005260:Female; D005455:Fluorescent Antibody Technique; D005755:Gastrins / Q000097:blood; D005756:Gastritis / Q000473:pathology*; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011706:Pyloric Antrum / Q000166:cytology* / Q000473:pathology
D005755:Gastrins