Studies on the effects of heterologous antisera against subcellular thymocyte fraction.
Subcellular fractions of mice thymocytes were used for sensitization of rabbits. The antisera were examined for their immunosuppressive potency in vivo by allogeneic murine tumor metastases system and on skingraft survival and in vitro by leukocyte agglutination tests. The results indicated that the most potent immunosuppressive antisera was that against the second fraction (Fr. 2) of the detergent soluble endoplasmic reticulum fraction from thymocytes.
D000372:Agglutination Tests; D000818:Animals; D000961:Antilymphocyte Serum; D007165:Immunosuppression Therapy; D008207:Lymphatic Metastasis; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D011817:Rabbits; D012509:Sarcoma / Q000276:immunology; D016038:Skin Transplantation; D013601:T-Lymphocytes; D014184:Transplantation, Homologous
D000961:Antilymphocyte Serum