[Experimental studies on the antimicrobial effect of several butylcyanoacrylate tissue adhesives].
It is dealt with the effects of various butycyano-acrylate type surgical adhesives on gram-positive and gram-negative bacterial species. The experimental results show a growth-inhibiting effect on gram-positive germs. Gram-negative germs are not affected. The growth inhibition produced by SO2-containing adhesives is greater than that caused by SO2-free ones. As compared to Histoacryl blue, the Fimomed variants showed a broader spectrum. Furthermore, it was stated that the adhesive exerts its growth-inhibiting effect not only in the monomeric, but also in the polymeric state. A relationship between the gram-behaviour and the antimicrobic effect of the adhesive is taken into consideration.
D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D003352:Corynebacterium / Q000187:drug effects; D003487:Cyanoacrylates / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004659:Enbucrilate / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D011549:Pseudomonas / Q000187:drug effects; D013291:Streptococcus / Q000187:drug effects; D013458:Sulfur Dioxide / Q000494:pharmacology; D014014:Tissue Adhesives
D000891:Anti-Infective Agents, Local; D003487:Cyanoacrylates; D014014:Tissue Adhesives; D013458:Sulfur Dioxide; D004659:Enbucrilate
Experimentelle Untersuchungen zur antimikrobiellen Wirkung von einigen Butylzyanoakrylatgewebeklebern.