Factors which have a significant effect on the survival of human skin grafts.
Survival of 436 ABO-compatible skin grafts exchanged in 97 Caucasian families was prolonged if donor and recipient were genotypically, as compared with phenotypically, HLA identical. Among skin grafts between haploidentical family members, a mismatch at the A locus was equivalent to a mismatch at the B locus. Skin grafted from child to mother survived longer than did skin grafted between other family members, other variables being equivalent. A highly significant positive correlation was found between the age of recipient and skin graft survival. In addition, a significant interaction was found between the relationship of donor and recipient and degree of antigen match.
D006085:Graft Survival; D006680:HLA Antigens; D006801:Humans; D016038:Skin Transplantation; D014019:Tissue Donors; D014184:Transplantation, Homologous
D006680:HLA Antigens