Etomidate in a new solvent. A clinical evaluation.
The introduction of polyethylene glycol as a solvent for etomidate appears to markedly reduce the incidence of pain on injection while maintaining the previously demonstrated advantageous features of cardiovascular stability and rapid recovery.
D000771:Anesthesia, Intravenous; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D005045:Etomidate / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D010146:Pain / Q000139:chemically induced; D011092:Polyethylene Glycols / Q000494:pharmacology
D007093:Imidazoles; D011092:Polyethylene Glycols; D005045:Etomidate