[Leukocyte adhesion suppression reaction for determining the immunological reactivity of oncological patients].
By means of the reaction of inhibition of leucocytes adhesiveness, suggested by Halliday and his coworkers, the authors examined the immune reactivity of 52 oncological patients and 25 healthy donors. The specific cell activity was observed only in oncological patients, and mainly against the antigen from autologous or histologically identical tumor. In a third of patients under examination blood serum would block the specific cell activity. The intensity of the reaction was enhanced in immunotherapy with FHA activated lymphocytes. The sensitivity of the reaction involved proved to be higher than that of the reaction of lymphocytes migration inhibition by the same antigens.
D000937:Antigen-Antibody Reactions; D000951:Antigens, Neoplasm / Q000008:administration & dosage; D002448:Cell Adhesion; D002464:Cell Migration Inhibition; D002986:Clinical Trials as Topic; D006801:Humans; D007167:Immunotherapy; D007962:Leukocytes / Q000276:immunology*; D009369:Neoplasms / Q000276:immunology*
D000951:Antigens, Neoplasm
Reaktsiia podavleniia prilipaniia leĭkotsitov dlia opredeleniia immunologicheskoĭ reaktivnosti onkologicheskikh bol'nykh.