A direct confirmation of the specificity of mutation frequency decline for suppressor mutations.
In a phage T7-resistand and galactose-sensitive derivative of E. coli B/r trp- it has been possible to show that MFD for UV-induced mutations is specific for Trp+ reversions (mainly of an ochre suppressor-containing type) but is without effect on galactose-resistant or D-fucose-resistant (ara Cc) forward mutations.
D004926:Escherichia coli / Q000235:genetics* / Q000528:radiation effects; D005643:Fucose / Q000378:metabolism; D005690:Galactose / Q000378:metabolism; D009154:Mutation / Q000528:radiation effects*; D013489:Suppression, Genetic / Q000528:radiation effects*; D014364:Tryptophan / Q000378:metabolism; D014466:Ultraviolet Rays
D005643:Fucose; D014364:Tryptophan; D005690:Galactose