Somatostatin and diabetes.
Somatostatin may act as a local regulator of endocrine and exocrine secretion and as a peptidergic neurotransmitter rather than as a classical circulating hormone. The possible physiologic role of its secretion in the regulation of islet A and B cell function, and particularly its significance in nutrient homeostasis and diabetes, are discussed.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000503:physiopathology*; D006706:Homeostasis / Q000187:drug effects; D006801:Humans; D007515:Islets of Langerhans / Q000502:physiology / Q000503:physiopathology; D010179:Pancreas / Q000166:cytology; D013004:Somatostatin / Q000378:metabolism / Q000494:pharmacology / Q000502:physiology* / Q000627:therapeutic use
D001786:Blood Glucose; D013004:Somatostatin