The relationship between carcinogenicity and mutagenicity of some polynuclear hydrocarbons.
25 polynuclear hydrocarbons were tested for mutagenicity using the Ames Assay and the results were compared with existing carcinogenicity data. The assessment of the predictive value of this particular short-term test showed a 58% positive and a 41% negative correlation.
D001551:Benz(a)Anthracenes / Q000494:pharmacology*; D001580:Benzopyrenes / Q000494:pharmacology*; D002273:Carcinogens; D004305:Dose-Response Relationship, Drug; D005821:Genetic Techniques; D009153:Mutagens; D012486:Salmonella typhimurium
D001551:Benz(a)Anthracenes; D001580:Benzopyrenes; D002273:Carcinogens; D009153:Mutagens