Effects of pregnancy on the glucose-induced insulin release from cultivated pancreatic islets of the rat.
7-day-cultured islets from pregnant Wistar rats released at 5.6 mM glucose significantly more insulin than islets from nonpregnant rats, whereas in vivo this heigthened glucose sensitivity is lost 48 h post partum.
D000818:Animals; D001786:Blood Glucose; D002478:Cells, Cultured; D005260:Female; D005865:Gestational Age; D005947:Glucose / Q000494:pharmacology*; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects* / Q000378:metabolism; D011247:Pregnancy; D011270:Pregnancy, Animal; D051381:Rats
D001786:Blood Glucose; D007328:Insulin; D005947:Glucose