[Mechanism of the reaction of substrate phosphorylation in the tricarboxylic acid cycle].
The suggested sequence of the reactions differs from those presented in literature and includes the following compounds as intermediate ones: the complex of enzyme having 2ATP and two residues of phosphoric acid; the complex of enzyme having four residues of phosphoric acid; the complex of enzyme containing two residues of phosphoric acid and two residues of succinic acid. Sequences of the reactions suggested in literature involve as intermediate compounds a phosphorylated derivative of the enzyme (E--P), phosphorylated derivative CoA linked with the enzyme (E.CoA--P), a high-ergic compound of the enzyme with CoA (E.CoA) and succinyl phosphate linked with the enzyme (E.succinyl--P).
D000255:Adenosine Triphosphate / Q000378:metabolism*; D002952:Citric Acid Cycle; D003065:Coenzyme A / Q000378:metabolism; D013386:Succinates / Q000378:metabolism
D013386:Succinates; D000255:Adenosine Triphosphate; D003065:Coenzyme A
Mekhanizm reaktsii substratnogo fosforilirovaniia v tsikle trikarbonovykh kislot.