[Effect of the alpha-fraction of human blood plasma on the cellular and humoral immune response in mice and rats].
Th author describes the influence of the fraction Con-I-A of human plasma on the survival of skin transplantant in mice and the influence of the same fraction as well as human ceruloplasmin (purity over 97%) on the production of hemagglutinins in rats. In the nontreated animals with alpha-fraction the transplanted skin from C57BI/10 on BIOCZH survived on the average 7,5 +/- 0,54, but in the treated animals--8,56 +/- 0,55. Titers of hemagglutinins in Wistar rats, immunized with 0, Rh--human erythrocytes was 11,6 +/- 3,5 in nontreated animals on the fifth day, but in the treated animals with alphafraction the titre was 9,5 +/- 1,35 and 5,3 +/- 1,78 in the treated animals with ceruloplasmin.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D001798:Blood Proteins / Q000276:immunology*; D002570:Ceruloplasmin / Q000494:pharmacology; D006388:Hemagglutinins / Q000032:analysis; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D007114:Immunization; D007165:Immunosuppression Therapy; D051379:Mice; D051381:Rats; D016038:Skin Transplantation; D013997:Time Factors; D014181:Transplantation Immunology / Q000187:drug effects
D001798:Blood Proteins; D006388:Hemagglutinins; D002570:Ceruloplasmin
Vliianie na al'fa-fraktsiia ot choveshka kruvna plazma vurkhu kletuchniia i khumoralniia imunen otgovor u mishki i plukhove.