[Desquamative interstitial pneumonia. Peripheral eosinophilia in DIP: a new clinical aspect (author's transl)].
It were Liebow et al. (1965) who, for the first time, described the desquamative interstitial pneumonia (DIP) as one clinical and morphological unit. The etiopathology of this disease is still unknown and there exist many controversial opinions as to its role within the interstitial pneumonias. For the clinical-physician the DIP represents a difficult problem because there seems to be no uniform appearance to this disease. So a lung-biopsy is the unique way to make a definitive diagnosis. The following description represents a case of DIP observed at our hospital. At the same time we tried to give a review of our present knowledge concerning the morphology, course and therapy of this disease. We think it should be note that the DIP was accompanied by an extreme peripheral eosinophilia. To our knowledge this is the first time such a phenomenon is described. In the course of the treatment with steroids the eosinophilia disappeared parallel to the normalization of the radiographic findings.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D000542:Alveolitis, Extrinsic Allergic / Q000175:diagnosis; D003095:Collagen Diseases / Q000175:diagnosis; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D008168:Lung / Q000000981:diagnostic imaging; D011014:Pneumonia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011657:Pulmonary Eosinophilia / Q000175:diagnosis; D011859:Radiography; D012293:Rifampin / Q000627:therapeutic use; D013752:Tetracycline / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D013752:Tetracycline; D007538:Isoniazid; D012293:Rifampin
Desquamative interstitielle Pneumonie Periphere Eosinophilie bei DIP: ein neuer klinischer Aspekt.