title: [Therapy of duodenal ulcer using cimetidine].
abstract: 55 patients with endoscopically confirmed duodenal ulcers received either cimetidine (26 patients) or placebo (29 patients) in a double-blind trial. At four weeks, 85% of the patients treated with cimetidine and 62% of those receiving placebo had endoscopically healed ulcers. This difference is not statistically significant. However, patients on cimetidine showed a more rapid and statistically significant reduction in the size of their ulcers.
mesh_terms: D002927:Cimetidine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004381:Duodenal Ulcer / Q000188:drug therapy*; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D010919:Placebos
chemical_list: D006146:Guanidines; D010919:Placebos; D002927:Cimetidine
vernacular_title: Traitement de l'ulcère duodénal par la cimétidine.