Variability of gingival bleeding in experimental gingivitis trials.
Gingival bleeding is a difficult parameter to assess in experimental trials. The Confirmed Bleeding Day was recently developed as a measurement for this purpose. It was observed that considerable variations existed between the measurements made in a pilot study and an experimental trial, and these variations were subjected to a statistical analysis. The reasons for the variations are discussed, and recommendations made for the design of experimental trials involving gingival bleeding.
D002710:Chlorhexidine / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D005884:Gingival Hemorrhage / Q000188:drug therapy; D005891:Gingivitis / Q000188:drug therapy; D006801:Humans; D009067:Mouthwashes; D006472:Oral Hemorrhage / Q000188:drug therapy; D010865:Pilot Projects
D009067:Mouthwashes; D002710:Chlorhexidine