A triple test for screening biological activity of prostacyclin analogues.
6,9-Thiaprostacyclin was used as a representative of prostacyclin analogues with the aim to design the most convenient procedure for evaluation of vasodilator, anti-platelet and other biological properties within this new group of potential anti-thrombotic agents.
D001681:Biological Assay; D001808:Blood Vessels; D004353:Drug Evaluation, Preclinical / Q000379:methods; D011464:Epoprostenol / Q000494:pharmacology; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010974:Platelet Aggregation / Q000187:drug effects; D011453:Prostaglandins / Q000494:pharmacology; D011465:Prostaglandins, Synthetic; D014666:Vasomotor System / Q000187:drug effects
D011453:Prostaglandins; D011465:Prostaglandins, Synthetic; D011464:Epoprostenol