The effect of Procion Blue on certain metabolic activities of Streptococcus mutans.
Metabolic activities of S mutans were selectively affected by Procion Blue, known to cause covalent bonds and stable cross links in relation to carbohydrate and protein. In this study, despite the reduction in extra polysaccharide, the level of activity of glucosyltransferase was not significantly changed from the control level and colonial morphology was not transformed from smooth to rough. The results of the investigation imply at least interference with formation of extra cellular polysaccharide, possibly in the bacterial cell wall.
D001431:Bacteriological Techniques; D002473:Cell Wall / Q000378:metabolism; D004396:Coloring Agents / Q000494:pharmacology*; D005964:Glucosyltransferases / Q000032:analysis; D009994:Osmolar Concentration; D011134:Polysaccharides / Q000378:metabolism*; D013045:Species Specificity; D013295:Streptococcus mutans / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*
D004396:Coloring Agents; D011134:Polysaccharides; D005964:Glucosyltransferases