Identification of an isoquinoline alkaloid after chronic exposure to ethanol.
A rapid and simple method for extraction of biogenic amines from small tissue samples was used to examine striata from ethanol-treated mice for TIQs. The results indicate that chronic ethanol administration can induce the formation of MSAL in striatal tissue.
D000437:Alcoholism / Q000378:metabolism*; D000470:Alkaloids / Q000032:analysis; D000818:Animals; D002395:Catecholamines / Q000032:analysis; D002849:Chromatography, Gas; D003342:Corpus Striatum / Q000032:analysis* / Q000187:drug effects; D000431:Ethanol / Q000494:pharmacology; D006801:Humans; D007546:Isoquinolines / Q000032:analysis*; D051379:Mice; D008813:Mice, Inbred ICR
D000470:Alkaloids; D002395:Catecholamines; D007546:Isoquinolines; D000431:Ethanol