title: The metabolism of glucose in pancreatic islets.
abstract: Some quantitative aspects of glucose metabolism in isolated pancreatic islets are reviewed, with emphasis on the measurement of metabolic fluxes, substrate concentrations and enzyme activities. The influence of the environmental glucose concentration upon the production rate of metabolic end-products, and the intracellular concentration of both metabolites and co-factors is also considered.
mesh_terms: D000818:Animals; D001692:Biological Transport; D002952:Citric Acid Cycle; D005260:Female; D005941:Glucokinase / Q000378:metabolism; D005947:Glucose / Q000502:physiology*; D005958:Glucosephosphates / Q000096:biosynthesis; D006003:Glycogen / Q000378:metabolism; D006019:Glycolysis; D006593:Hexokinase / Q000378:metabolism; D007515:Islets of Langerhans / Q000378:metabolism*; D007773:Lactates / Q000378:metabolism; D008297:Male; D010084:Oxidation-Reduction; D010428:Pentosephosphates / Q000378:metabolism; D011773:Pyruvates / Q000378:metabolism; D051381:Rats; D013012:Sorbitol / Q000378:metabolism; D014306:Trioses / Q000378:metabolism
chemical_list: D005958:Glucosephosphates; D007773:Lactates; D010428:Pentosephosphates; D011773:Pyruvates; D014306:Trioses; D013012:Sorbitol; D006003:Glycogen; D006593:Hexokinase; D005941:Glucokinase; D005947:Glucose