Specific inhibition of human group I pepsins by two pepsin inhibitiors.
Two pepsin-inhibitors, a peptide produced by Streptomyces EF-44-201 and a peptide produced by Actinomycetes have been found to inactivate completely the human group I pepsin, but to have little activity against the group II pepsins.
D006801:Humans; D010434:Pepsin A / Q000037:antagonists & inhibitors*; D010436:Pepstatins / Q000494:pharmacology; D010455:Peptides / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D010436:Pepstatins; D010455:Peptides; D010434:Pepsin A