[Proliferation of the exocrine and endocrine portions of the pancreas after its resection].
A weak regenerative capacity of the pancreas was revealed after the resection of about 40 per cent of the tissue of this organ in mice-hybrids CBA X C57BL/6, weighing 20--28 g. During the 21 days of the experiment there was no significant restoration of the pancreas weight. An increase of the proliferative activity (the number of mitoses and daily fraction of the thymidine-3H-labeled cells were counted) was brief and failed to spread over the whole organ. The maximal number of the labeled nuclei in the epithelium of the acini and the islets was found in the area near the wound where the organ tissue was somewhat edematous. In the areas near the wound surface, but unaffected, the labeled cells count was increased during the early post-operative period only. The number of labeled cells of the islets and acini of the pancreas in the areas distant from the wound (in the loop of the duodenum) was no different from the control. The number of labeled cells in the islets was greater than in the acini.
D000818:Animals; D006824:Hybridization, Genetic; D007515:Islets of Langerhans / Q000502:physiology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008938:Mitosis; D010179:Pancreas / Q000502:physiology*; D010180:Pancreatectomy; D012038:Regeneration; D013997:Time Factors
O proliferatsii ékzokrinnogo i éndokrinnogo otdelov podzheludochnoĭ zhelezy posle ee rezektsii.