title: [Early or malignant ulcerative syphilis. Considerations apropos of 2 cases. Bibliographic analysis].
abstract: Two cases of early ulcerative syphilis observed in the city of La Plata, Argentina, in the last 13 years are presented. Cases n.o 1, classified as Queyrat type, was in a previously bad general condition, due both to excessive smoking and alcoholism and showed a classic blood serologic test, that was slightly reactive. Case n.o 2, Milian type, presented a previously excellent general condition. The classic blood serologic test and FTAabs. were strongly reactive. It showed only a significant depression of cell immunity, with regard to the bacterial cutaneous proofs (bacterial skin-tests) carried out "in vivo". In both cases the clinical aspect was similar, with ulcerative necrotic lesions and affectation of the general condition which coincided with the outbreak of those lesions. The response to treatment was good, with rapid improvement of the general condition while the improvement of the skin lesions was slower and occurred only within 3 weeks.
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D010401:Penicillin G Benzathine / Q000627:therapeutic use; D012867:Skin / Q000473:pathology; D013587:Syphilis / Q000188:drug therapy / Q000473:pathology*; D014456:Ulcer / Q000209:etiology
chemical_list: D010401:Penicillin G Benzathine
vernacular_title: Lúes ulcerativa precoz o maligna. Consideraciones a propósito de dos casos. Análisis bibliográfico.