title: [Ribosome binding to the membranes of Candida albicans].
abstract: The in vitro binding of free ribosomes to the membranes of polyenoic antibiotics-sensitive and resistant strains of Candida albicans, considerably differing in the composition of their sterol components, was studied. It was shown that the extent and type of membrane-ribosome interaction is similar in both cases. The dependence of binding on ribosome concentration in the incubation mixture is double-phase, as was shown for different membrane fractions of both sensitive and resistant strains. The role of lipid membrane components, particularly that of sterols in the membrane-ribosome interactions is discussed.
mesh_terms: D002176:Candida albicans / Q000648:ultrastructure*; D002462:Cell Membrane / Q000648:ultrastructure; D012270:Ribosomes / Q000648:ultrastructure*; D013045:Species Specificity; D013261:Sterols / Q000032:analysis
chemical_list: D013261:Sterols
vernacular_title: Sviazyvanie ribosom s membranami Candida albicans.