A new plastic receptacle for solid phase immunoassays.
A new, simple, inexpensive plastic device for solid phase immunoassay, the through-passage receptacle (TPR), with a large ratio of surface area to volume, is described. It was substantially more efficient in non-specific protein adsorption and specific immunological binding than the conventional wells of microtiter plates. It was also easier to wash since washing was facilitated by a through-passage with a gravity flow. This device, which should be more conducive to automation than currently used receptacles, should increase the sensitivity and decrease the incubation time of the solid phase immunoassay technique.
D001666:Binding Sites, Antibody; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation; D007163:Immunosorbent Techniques; D011137:Polystyrenes; D011506:Proteins; D013997:Time Factors
D011137:Polystyrenes; D011506:Proteins