Lymphographic diagnosis of malignant lymphoma in the course of Sjögren's syndrome.
Three patients with Sjögren's syndrome complicated by malignant lymphoma are presented. During the benign stage, two showed non-specific hyperplastic lymph node patterns on lymphography. When the disease had become malignant, all cases revealed generalized involvement of the retroperitoneal lymph nodes. The lymphographic pattern was that of a malignant lymphoma: enlarged nodes, with a foamy, linear or reticular appearance but mostly preserved marginal sinuses. On lymphographic follow-up, the node alterations were consistent with the histological findings and the clinical status, including the therapeutic response.
D000328:Adult; D005260:Female; D006801:Humans; D008198:Lymph Nodes; D008220:Lymphography; D008223:Lymphoma / Q000150:complications / Q000000981:diagnostic imaging*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications*