Effect of hyperbaric oxygen on certain growth features of Candida albicans.
Candida albicans (Robin) Berkhout, isolated from an adult female with recurring candidiasis, was tested in vitro for macroscopic and microscopic growth features at varying hyperbaric oxygen levels and at various exposure times and intervals. The organism was found to be inhibited within a pressure/time range well tolerated by human subjects, suggesting that hyperbaric oxygen might be used successfully in treating human candidiasis. Overall experimental results provide an in vitro basis for use of compression chamber therapy in candidiasis treatment.
D001274:Atmospheric Pressure; D002176:Candida albicans / Q000187:drug effects / Q000254:growth & development*; D010100:Oxygen / Q000494:pharmacology*; D013997:Time Factors
D010100:Oxygen