title: An evaluation of prophylactic doxycycline in hysterectomy patients.
abstract: Although data now exist that the use of prophylactic antibiotics reduces postoperative febrile morbidity in hysterectomy patients, some controversy remains about this point of view. This prospective, double-blind, randomized study evaluated the use of doxycycline before and during the first three postoperative days after abdominal and vaginal hysterectomy in private patients. The results indicate a reduction in the febrile morbidity in the drug group as compared to the placebo group.
mesh_terms: D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004318:Doxycycline / Q000008:administration & dosage / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007045:Hysterectomy, Vaginal; D007902:Length of Stay; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies
chemical_list: D004318:Doxycycline