title: Fertility problems in the renal transplant patient.
abstract: Renal function, and pituitary and testicular hormone levels were correlated with spermatogenesis in 7 male patients who had undergone successful kidney transplantations. Functions of the pituitary-Leydig cell axis were not impaired. However, abnormal renal function had a direct adverse affect on spermatogenesis. Mechanisms causing infertility in post-transplant patients are reviewed.
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000009:adverse effects; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007248:Infertility, Male / Q000139:chemically induced / Q000209:etiology*; D007668:Kidney / Q000503:physiopathology; D016030:Kidney Transplantation; D007985:Leydig Cells / Q000502:physiology; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010902:Pituitary Gland / Q000503:physiopathology; D011183:Postoperative Complications; D011239:Prednisolone / Q000009:adverse effects; D011241:Prednisone / Q000009:adverse effects; D013091:Spermatogenesis / Q000187:drug effects; D013739:Testosterone / Q000097:blood; D014184:Transplantation, Homologous; D014511:Uremia / Q000378:metabolism
chemical_list: D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D011239:Prednisolone; D001379:Azathioprine; D011241:Prednisone