Atypical isolate of Cryptococcus neoformans cultured from sputum of a patient with pulmonary cancer and blastomycosis.
Cryptococcus neoformans was isolated repeatedly from a patient with epider-moid carcinoma and pulmonary blastomycosis. The isolate was atypical in that it had only a minute capsule, caused persistent infection but no perceptible disease in mice, and initially appeared not to assimilate trehalose. Only after an incubation of 2 to 3 weeks did utilization of this substrate become apparent.
D000368:Aged; D001759:Blastomycosis / Q000150:complications / Q000382:microbiology*; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000382:microbiology*; D003454:Cryptococcus / Q000302:isolation & purification*; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D006801:Humans; D008172:Lung Diseases, Fungal / Q000382:microbiology*; D008175:Lung Neoplasms / Q000150:complications / Q000382:microbiology*; D008297:Male