title: Toxin from the culture filtrate of Shigella dysenteriae that causes morphological changes in Chinese hamster ovary cells and is distinct from the neurotoxin.
abstract: A toxin that causes morphological changes in Chinese hamster ovary cells was isolated from a culture filtrate of Shigella dysenteriae 1. It was partially purified by successive column chromatography on diethylaminoethyl-cellulose, Bio-Gel A-5m, and hydroxylapatite. The toxin was separated from neurotoxin by diethylaminoethyl-cellulose column chromatography and was not lethal for mice.
mesh_terms: D001427:Bacterial Toxins / Q000302:isolation & purification / Q000494:pharmacology*; D002460:Cell Line; D002478:Cells, Cultured / Q000166:cytology / Q000187:drug effects*; D012762:Shigella dysenteriae
chemical_list: D001427:Bacterial Toxins