An evaluation of Tween 80 effects on the survival and DNA repair in Escherichia coli following UV or gamma irradiation.
The notion that Tween 80 may be a DNA-repair inhibitor was tested with Escherichia coli. The results indicate that cell growth, colony-forming ability, and the rate and extent of removal of thymine-containing dimers from DNA are unchanged in the presence of Tween 80. We conclude that this detergent does not increase or diminish the effect of UV or gamma irradiation to bacteria.
D004260:DNA Repair / Q000187:drug effects*; D004269:DNA, Bacterial / Q000378:metabolism / Q000528:radiation effects; D004926:Escherichia coli / Q000378:metabolism / Q000528:radiation effects; D005720:Gamma Rays; D011092:Polyethylene Glycols / Q000494:pharmacology*; D011136:Polysorbates / Q000494:pharmacology*; D011740:Pyrimidine Dimers / Q000378:metabolism; D014466:Ultraviolet Rays
D004269:DNA, Bacterial; D011136:Polysorbates; D011740:Pyrimidine Dimers; D011092:Polyethylene Glycols