title: Abortive development of Wuchereria bancrofti in a West African strain of Culex pipiens fatigans.
abstract: The detailed morphology of the larvae of Wuchereria bancrofti developing in a refractory strain of Culex pipiens fatigans from Liberia, West Africa, has been described. The abortive development of the parasite in the thoracic muscles of the mosquito was characterized mainly by: (i) retardation or complete failure of initial division of the G-cell, (ii) partial or complete encapsulation of developing larvae, especially at the anal and excretory vesicle areas of late first-stage, (iii) breakdown of the forming internal structures with formation of clusters of DNA-and RNA-positive material, and (iv) anomalous development of some larvae in which extra-corporeal growth of internal tissues took place.
mesh_terms: D000354:Africa, Western; D000818:Animals; D000852:Anopheles / Q000469:parasitology; D003465:Culex / Q000469:parasitology*; D007303:Insect Vectors; D007814:Larva / Q000033:anatomy & histology / Q000254:growth & development; D008543:Melanins; D013045:Species Specificity; D014957:Wuchereria / Q000254:growth & development*; D014958:Wuchereria bancrofti / Q000033:anatomy & histology / Q000254:growth & development*
chemical_list: D008543:Melanins