Aspergillus pneumonia--a cluster of four cases in an intensive care unit.
Four cases of Aspergillus pneumonia occurred in an intensive care unit within a short period. Clusters of cases of invasive aspergillosis are rare and have usually been attributed to excessive contamination of the environment. Extensive environmental studies were, however, negative. Three of the cases were diagnosed ante mortem. One patient survived after early initiation of treatment with amphotericin B.
D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy; D001232:Aspergillus fumigatus / Q000302:isolation & purification; D001249:Asthma / Q000150:complications; D004812:Epidemiologic Methods; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications; D006801:Humans; D007362:Intensive Care Units; D008172:Lung Diseases, Fungal / Q000175:diagnosis*; D008173:Lung Diseases, Obstructive / Q000150:complications; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000175:diagnosis* / Q000188:drug therapy; D011112:Polymyxin B / Q000627:therapeutic use; D013019:South Africa
D011112:Polymyxin B