title: First experiences with HLA-matched corneal grafts in high risk cases.
abstract: In highly vascularized corneas the number of graft failures caused by irreversible rejections is higher than in non-or slightly vascularized corneas. The importance of antigen compatibility is demonstrated, especially in these 'high risk' cases. Ten highly vascularized corneas were grafted with HLA-matched donor material; only one reversible rejection was seen in this group. Nine non-or slightly vascularized corneas were grafted with donor material chosen a random. Retrospective HLA matching was performed. Three irreversible rejections were seen in this group. The number of HLA incompatibilities was high.
mesh_terms: D016039:Corneal Transplantation; D006680:HLA Antigens / Q000032:analysis*; D006650:Histocompatibility Testing / Q000379:methods; D006801:Humans; D011183:Postoperative Complications; D014184:Transplantation, Homologous
chemical_list: D006680:HLA Antigens