Treatment of psoriasis with 8-methoxypsoralen and sunlight.
Photochemotherapy with 8-methoxypsoralen and sunlight (PUVA-SOL), administered three times weekly, proved effective in the treatment of psoriasis. Weekend photochemotherapy (modified PUVA-SOL) also appeared useful as an adjunct to standard topical corticosteroid therapy. Careful measurement of ambient long-wave ultraviolet light (UVA) in the treatment locale and respect for the phototoxic potential of PUVA-SOL are necessary for success. The long-range toxicity of psoralen photochemotherapy remains undetermined.
D000287:Administration, Topical; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005069:Evaluation Studies as Topic; D006801:Humans; D008730:Methoxsalen / Q000627:therapeutic use*; D010778:Photochemotherapy; D011565:Psoriasis / Q000188:drug therapy*; D013472:Sunlight; D014221:Triamcinolone / Q000627:therapeutic use*
D014221:Triamcinolone; D008730:Methoxsalen