Endotoxemia and adrenaline-hyperreactive death in mice.
Mice given i.v. a sublethal dose of endotoxin in advance died with shock-like symptoms on administration of sublethal adrenaline dose. The lethal adrenaline-hyperreaction induced by endotoxin appeared gradually within a few h, showed maximum response after several h and almost disappeared 24 h after endotoxin administration.
D000818:Animals; D004731:Endotoxins / Q000008:administration & dosage / Q000633:toxicity*; D004837:Epinephrine / Q000633:toxicity*; D004926:Escherichia coli; D005260:Female; D008070:Lipopolysaccharides / Q000633:toxicity; D051379:Mice; D012772:Shock, Septic / Q000209:etiology
D004731:Endotoxins; D008070:Lipopolysaccharides; D004837:Epinephrine