Use of bacteriophage nucleic acid inducers of interferon in man.
The interest in therapeutic exploration of phage ds-RNAs is motivated by their antiviral and immunoregulatory activities. Preliminary studies in man indicate that topical application of native ds-RNAs represents no health-hazard to patients and may be beneficial in the therapy of viral skin and eye diseases.
D000818:Animals; D003090:Coliphages / Q000378:metabolism; D004341:Drug Evaluation; D004342:Drug Hypersensitivity; D005128:Eye Diseases / Q000188:drug therapy; D006561:Herpes Simplex / Q000188:drug therapy; D006801:Humans; D007369:Interferon Inducers / Q000494:pharmacology*; D007372:Interferons / Q000096:biosynthesis*; D012367:RNA, Viral / Q000494:pharmacology* / Q000633:toxicity; D012874:Skin Diseases, Infectious / Q000188:drug therapy; D014777:Virus Diseases / Q000188:drug therapy
D007369:Interferon Inducers; D012367:RNA, Viral; D007372:Interferons