A single mutation affects L-serine deaminase, L-leucyl-, L-phenylalanyl-tRNA protein transferase, and proline oxidase activity in Escherichia coli K-12.
A mutation at a single locus, wyb, results in several phenotypic changes in Escherichia coli K-12. The Wyb- phenotype includes: (i) an increase in L-serine deaminase activity, together with a loss of inducibility by L-leucine; (ii) an absence of L-leucyl-, L-phenylalanyl-tRNA protein transferase activity; (iii) inducibility of proline oxidase by proline; and (iv) a loss of ability to use maltose as a carbon and energy source.
D000217:Acyltransferases / Q000378:metabolism*; D004790:Enzyme Induction; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D005796:Genes; D012695:L-Serine Dehydratase / Q000378:metabolism*; D007930:Leucine; D008320:Maltose / Q000378:metabolism; D009154:Mutation; D010105:Oxygenases / Q000096:biosynthesis*; D011392:Proline; D012343:RNA, Transfer
D008320:Maltose; D012343:RNA, Transfer; D011392:Proline; D010105:Oxygenases; D000217:Acyltransferases; D012695:L-Serine Dehydratase; D007930:Leucine