Immunoglobulins and complement in human periodontitis.
The gingiva in human periodontitis shows IgG, IgM, and C3 suggesting an antigen-antibody response binding and activating complement. The irregular distribution of the fluorescence on the basement membrane suggests binding of antigen-antibody complexes.
D000936:Antigen-Antibody Complex; D000937:Antigen-Antibody Reactions; D001485:Basement Membrane / Q000276:immunology; D003176:Complement C3 / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D005881:Gingiva / Q000276:immunology; D005891:Gingivitis / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D010518:Periodontitis / Q000276:immunology*
D000936:Antigen-Antibody Complex; D003176:Complement C3; D007074:Immunoglobulin G; D007075:Immunoglobulin M