The immunological classification of acute lymphoblastic leukemias.
The main methods used in order to assess the immunological markers on the blast cells from patients with acute lymphoblastic leukemia (ALL) are critically evaluated. The classification of ALL according to the phenotype of the leukemic cells and their presumed origin is reviewed. The correlations with clinical features and prognosis, as well as their possible therapeutic implications, are discussed.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000951:Antigens, Neoplasm; D001402:B-Lymphocytes / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006412:Hematopoietic Stem Cells / Q000276:immunology; D006801:Humans; D007141:Immunoglobulin Fc Fragments; D007075:Immunoglobulin M; D007223:Infant; D007945:Leukemia, Lymphoid / Q000145:classification / Q000276:immunology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011947:Receptors, Antigen, B-Cell; D012075:Remission, Spontaneous; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology; D013997:Time Factors
D000951:Antigens, Neoplasm; D007141:Immunoglobulin Fc Fragments; D007075:Immunoglobulin M; D011947:Receptors, Antigen, B-Cell