title: Poor hypotensive response and tachyphylaxis following intravenous labetalol.
abstract: Three renal patients with transplant kidneys and uncontrolled hypertension were treated with intravenous doses of labetalol. Only minor depressor effects were noted and tachyphylaxis developed in 1 patient. Other parenteral hypotensive agents reduced blood pressure satisfactorily.
mesh_terms: D000328:Adult; D004983:Ethanolamines / Q000627:therapeutic use*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007263:Infusions, Parenteral; D007275:Injections, Intravenous; D016030:Kidney Transplantation; D007741:Labetalol / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D013618:Tachyphylaxis; D013997:Time Factors; D014184:Transplantation, Homologous
chemical_list: D004983:Ethanolamines; D007741:Labetalol