title: Transposon-mediated insertion of R factor into bacterial chromosome.
abstract: Insertion of transposon T n1 into the E. coli JC411 chromosome results in a sharp increase of plasmid RP4 integration frequency. This effect is absent in JC1553 recA cells. The RP4 integration with the chromosome is probably accomplished via recA-dependent recombination between transposon Tn1 inserted into the chromosome and the same transposon in the RP4 plasmid.
mesh_terms: D000667:Ampicillin / Q000494:pharmacology; D002876:Chromosomes, Bacterial; D004926:Escherichia coli; D007612:Kanamycin / Q000494:pharmacology; D011815:R Factors; D011995:Recombination, Genetic; D013752:Tetracycline / Q000494:pharmacology
chemical_list: D007612:Kanamycin; D000667:Ampicillin; D013752:Tetracycline