Effects of terbutaline aerosol in reversible airway obstruction.
Aerosol terbutaline is an effective bronchodilator agent with at least a seven-hour duration of action in patients with reversible obstruction of the airways. Inhalation of up to 1.5 mg of this drug is not associated with significant alterations of pulse rate and blood pressure. Although a dose-related improvement of specific airway conductance was demonstrated 30 minutes after administration of the drug, no such effect was observed in measurements of the forced expiratory volume in one second.
D000336:Aerosols; D000368:Aged; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D001991:Bronchitis / Q000188:drug therapy* / Q000503:physiopathology; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos; D012123:Pulmonary Ventilation / Q000187:drug effects*; D013147:Spirometry; D013726:Terbutaline / Q000008:administration & dosage / Q000627:therapeutic use*
D000336:Aerosols; D010919:Placebos; D013726:Terbutaline