Maturation linked expression of a myeloid cell surface antigen.
An antiserum raised against myelomonocytic and monocytic leukaemia cells has been used to define a cell surface antigen shared by normal and leukaemic cells of the granulocyte and monocyte cell lines. The quantitative expression of this antigen was investigated using the Fluorescence Activated Cell Sorter and was shown to correlate with the degree of morphological maturation.
D000818:Animals; D000941:Antigens / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000032:analysis; D002454:Cell Differentiation; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology*; D003429:Cross Reactions; D003602:Cytotoxicity, Immunologic; D005333:Fetus; D005455:Fluorescent Antibody Technique; D006098:Granulocytes / Q000276:immunology; D006801:Humans; D007106:Immune Sera; D007951:Leukemia, Myeloid / Q000276:immunology*; D009000:Monocytes / Q000276:immunology; D011817:Rabbits / Q000276:immunology
D000941:Antigens; D000951:Antigens, Neoplasm; D007106:Immune Sera