title: Antiemetic effect of droperidol after ophthalmic surgery.
abstract: Postoperative nausea with emesis is an undesirable side effect of general anesthesia in patients who have undergone ophthalmic surgery. The antiemetic effect of intravenous droperidol (Inapsine) was measured in a double-blind, controlled study of 78 patients undergoing general (enflurane [Ethrane]) anesthesia for a variety of ophthalmic procedures. There was a significant difference in the incidence of postoperative nausea and/or emesis in the droperidol-treated group, 13 of 78 (16%) as compared with the control population (37 of 87 [42%]). No complications of droperidol administration were observed. Droperidol may be an effective antiemetic drug if used prophylactically in patients who receive general anesthesia for ophthalmic surgery.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000768:Anesthesia, General / Q000009:adverse effects*; D000932:Antiemetics; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004329:Droperidol / Q000494:pharmacology*; D005128:Eye Diseases / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D014839:Vomiting / Q000209:etiology
chemical_list: D000932:Antiemetics; D004329:Droperidol