Chemical and biological studies on indomethacin, sulindac and their analogs.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001597:Benzylidene Compounds / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D002462:Cell Membrane / Q000187:drug effects; D002464:Cell Migration Inhibition; D002986:Clinical Trials as Topic; D004220:Disulfides / Q000378:metabolism; D004347:Drug Interactions; D004791:Enzyme Inhibitors; D005342:Fibrinolysis / Q000187:drug effects; D006801:Humans; D007192:Indenes / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D007211:Indoles / Q000494:pharmacology; D007213:Indomethacin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D008247:Lysosomes / Q000187:drug effects; D010085:Oxidative Phosphorylation / Q000187:drug effects; D011453:Prostaglandins / Q000096:biosynthesis; D012216:Rheumatic Diseases / Q000188:drug therapy; D013329:Structure-Activity Relationship; D013438:Sulfhydryl Compounds / Q000378:metabolism
D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001597:Benzylidene Compounds; D004220:Disulfides; D004791:Enzyme Inhibitors; D007192:Indenes; D007211:Indoles; D011453:Prostaglandins; D013438:Sulfhydryl Compounds; D007213:Indomethacin