[Use of clofelin for arresting hypertensive crises].
The authors gave clophelin by intravenous (0.1 g) or intramuscular (0.1--0.15 mg) injections to 75 patients who were in a state of hypertensive crisis. In 67 patients (89--4%) the crisis was successfully arrested. In most patients maximum hypotensive effect occurred 10--20 minutes after intravenous injection and 20--30 minutes after intramuscular administration. Tolerance to a single injection of the drug was good. In some cases there was a marked additional fall of arterial pressure in the orthostatic position, a sensation of dryness in the mouth, weakness and mild somnolence.
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D003000:Clonidine / Q000008:administration & dosage / Q000627:therapeutic use*; D003971:Diastole / Q000187:drug effects; D004341:Drug Evaluation; D004630:Emergencies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D013599:Systole / Q000187:drug effects; D013997:Time Factors
D003000:Clonidine
Primenenie klofelina dlia kupirovaniia gipertonicheskikh krizov.