S-carboxymethylcysteine in the treatment of glue ear: a double blind trial.
A double blind trial was carried out comparing S-carboxymethylcysteine (S-CMC; Mucodyne, Berk Pharmaceuticals) with inert placebo in the treatment of glue ear in fifty-two children who had not previously undergone surgery for the condition. The results, analysed after three months of treatment failed to demonstrate a significant reduction in the number of children receiving S-CMC who eventually required surgery for the condition.
D002233:Carbocysteine / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D003545:Cysteine / Q000031:analogs & derivatives*; D004311:Double-Blind Method; D004341:Drug Evaluation; D006801:Humans; D010033:Otitis Media / Q000188:drug therapy*
D002233:Carbocysteine; D003545:Cysteine