title: Urinary tract infection in general practice.
abstract: In three studies, 616 patients (610 female and six male) presented with symptoms suggesting urinary tract infection (UTI). Of these, 321 had greater than 100 X 10(6) bacteria per litre in a midstream urine sample. None of the presenting symptoms could be considered to be a reliable indicator of bacteriuria. Ninety percent of infected urines and 44 percent of uninfected urines had a raised white cell concentration. Escherichia coli was the most common infecting organism (71.3 percent). Next were Gram positive cocci at 15.6 percent, Proteus mirabilis (7.5 percent), and Klebsiella-Enterobacter species (0.7 percent). At follow-up over 30 days 25.6 percent of patients initially infected again had infected urine. The organisms isolated from initial MSUs were sensitive to most antibacterial agents by disc-sensitivity testing. The expected urine levels of drugs used in the study greatly exceeded the measured minimum inhibitory concentration.
mesh_terms: D000293:Adolescent; D000658:Amoxicillin / Q000627:therapeutic use; D000667:Ampicillin / Q000627:therapeutic use; D004926:Escherichia coli / Q000302:isolation & purification; D005194:Family Practice; D005260:Female; D005500:Follow-Up Studies; D006089:Gram-Negative Anaerobic Bacteria / Q000302:isolation & purification; D006801:Humans; D007709:Klebsiella / Q000302:isolation & purification; D007958:Leukocyte Count; D008297:Male; D009268:Nalidixic Acid / Q000627:therapeutic use; D010093:Oxolinic Acid / Q000627:therapeutic use; D011247:Pregnancy; D011511:Proteus / Q000302:isolation & purification; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D009268:Nalidixic Acid; D000667:Ampicillin; D000658:Amoxicillin; D010093:Oxolinic Acid