Droperidol, fentanyl and morphine for i.v. surgical premedication.
Fentanyl 0.1 mg and morphine 10 mg alone and in combination with droperidol 2.5 and 5.0 mg were studied for i.v. surgical premedication in 240 patients. Relief of anxiety, sedation, lack of recall, patient acceptance and side-effects were evaluated. The addition of droperidol to fentanyl and morphine produced greater sedation and relief of anxiety before operation, but did not improve patient acceptance or lack of recall.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001007:Anxiety / Q000188:drug therapy; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004329:Droperidol / Q000008:administration & dosage; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D011939:Mental Recall / Q000187:drug effects; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage; D011229:Preanesthetic Medication; D013997:Time Factors
D009020:Morphine; D004329:Droperidol; D005283:Fentanyl