title: [The effect of various organochlorine pesticides on the immunologic reactivity of the white rat].
abstract: Wistar rats, aged 30 and 90 days, received Aldrin and Lindan treatment (8 ppm or 11 ppm) over 60 days, followed by inoculation of E. coli. The capacity of antibody formation was changed but not inhibited. Functional disorders occurred in the thymus (decline of nucleic acids), adrenal gland (decline of Vitamin C), and in the protein synthesis. The toxicity of even smaller Aldrin doses obviously was stronger than that of Lindan. The toxicity of either substance to younger animals was stronger than to individuals in more advanced age.
mesh_terms: D000311:Adrenal Glands / Q000032:analysis; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis*; D000917:Antibody Formation / Q000187:drug effects*; D000942:Antigens, Bacterial; D001205:Ascorbic Acid / Q000032:analysis; D002452:Cell Count; D004247:DNA / Q000032:analysis; D004926:Escherichia coli / Q000276:immunology; D007306:Insecticides / Q000009:adverse effects*; D007962:Leukocytes; D012313:RNA / Q000032:analysis; D051381:Rats; D013950:Thymus Gland / Q000032:analysis
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D007306:Insecticides; D012313:RNA; D004247:DNA; D001205:Ascorbic Acid
vernacular_title: Beitrag zum Einfluss einiger organochlorurierter Pestizide auf die immunologische Reaktivität der weissen Ratte.