Tooth allografts fail to stimulate immunologic memory in mice.
Tooth transplants should not preclude future transplants in the recipient. In this study teeth failed to stimulate immunologic memory in weakly disparate mice. The teeth did carry transplantation antigens and were rejected after second-set skin grafts. The teeth probably enhanced their own survival through some immunoregulatory mechanism.
D000818:Animals; D000941:Antigens; D003782:Dental Pulp / Q000033:anatomy & histology; D003786:Dental Pulp Cavity / Q000033:anatomy & histology; D006084:Graft Rejection; D006085:Graft Survival; D006650:Histocompatibility Testing; D007156:Immunologic Memory; D051379:Mice; D008815:Mice, Inbred Strains; D016038:Skin Transplantation; D014083:Tooth Germ / Q000033:anatomy & histology / Q000637:transplantation*; D014181:Transplantation Immunology; D014184:Transplantation, Homologous
D000941:Antigens