Immunofluorescence studies in reactional leprosy with relevance to treatment.
Twenty-three biopsies of skin lesions of patients with various types of leprosy, showing a recent reaction, were examined by means of immunofluorescence (IF) methods. The patients were divided into two groups according to the number of inflammatory cells, staining with various FTC-labelled anti-immunoglobulin antisera, in representative areas of the biopsies. It was found that the presence of these cells was correlated with a good response to thalidomide treatment.
D005455:Fluorescent Antibody Technique; D006801:Humans; D007918:Leprosy / Q000188:drug therapy / Q000276:immunology*; D013792:Thalidomide / Q000627:therapeutic use
D013792:Thalidomide