title: Influence of antibiotics on microbial intestinal transformation of cholesterol to coprostanol in man.
abstract: Fecal excretion of coprostanol was followed in groups of healthy volunteers receiving various antibiotics per os. No effect upon excretion was found in the groups receiving phenoximethylpenicillin or doxicycline, whereas a prolonged reduction was found in the groups receiving clindamycin, ampicillin, oxitetracycline or a fixed combination of bacitracin and neomycin.
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects / Q000378:metabolism*; D004083:Cholestanol / Q000378:metabolism*; D002784:Cholesterol / Q000031:analogs & derivatives* / Q000378:metabolism*; D002986:Clinical Trials as Topic; D005243:Feces / Q000032:analysis; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents; D004083:Cholestanol; D002784:Cholesterol