Evidence implicating the mononuclear phagocytic system of the rat in immunity to infections with Trypanosoma lewisi.
The present study emphasises the importance of the mononuclear phagocytic system of the rat in immunity to infections with Trypanosoma lewisi. Despite the great increase in the weight of the spleen, the liver played a major role in removing the parasites from the circulation. No evidence could be obtained that removal of the parasites was related to the lytic activity of specific antibody and complement.
D000818:Animals; D000917:Antibody Formation; D000918:Antibody Specificity; D003165:Complement System Proteins; D008099:Liver / Q000276:immunology; D051379:Mice; D009000:Monocytes / Q000276:immunology*; D010586:Phagocytes / Q000276:immunology*; D010587:Phagocytosis; D051381:Rats; D013154:Spleen / Q000276:immunology; D014350:Trypanosoma lewisi / Q000276:immunology; D014352:Trypanosomiasis / Q000276:immunology*
D003165:Complement System Proteins