The necessity for monitoring chloramphenicol levels when treating neonatal meningitis.
Chloramphenicol can be an effective agent in the treatment of ampicillin-resistant E. coli meningitis due to susceptible organisms in the premature or term infant. However, it can be used safely and effectively only if careful monitoring of serum levels is undertaken.
D002701:Chloramphenicol / Q000097:blood* / Q000627:therapeutic use; D004927:Escherichia coli Infections / Q000097:blood / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000097:blood / Q000188:drug therapy*; D008581:Meningitis / Q000097:blood / Q000188:drug therapy*; D008991:Monitoring, Physiologic
D002701:Chloramphenicol