Anti-lung antibodies associated with human lung allografts.
Serum specimens from 4 patients who had had a lung allograft were examined for anti-lung antibodies. Two patients developed antibodies after transplantation, and in 2, the antibodies increased in titer after an allograft. The absorption of the anti-lung antibody by fetal lung cell cultures, in contrast to the failure of absorption by kidney cell cultures from the same fetus, indicates that the antibody is lung specific.
D000918:Antibody Specificity; D001323:Autoantibodies; D002478:Cells, Cultured; D003165:Complement System Proteins; D003601:Cytotoxicity Tests, Immunologic; D005333:Fetus; D006801:Humans; D007668:Kidney / Q000166:cytology / Q000276:immunology; D008168:Lung / Q000166:cytology / Q000276:immunology*; D016040:Lung Transplantation; D014184:Transplantation, Homologous; D014343:Trypan Blue / Q000378:metabolism
D001323:Autoantibodies; D003165:Complement System Proteins; D014343:Trypan Blue