title: Protoplast-like structures formation from two species of Enterobacteriaceae by fosfomycin treatment.
abstract: A procedure for protoplasts formation from Escherichia coli and Serratia marcescens by treatment with fosfomycin alone is described. This method gives high and low yields of stable protoplasts from E. coli and S. marcescens respectively. In the last case numerous spheroplasts were obtained. Electron micrographs of intact cells, protoplasts and spheroplasts are shown.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002462:Cell Membrane / Q000648:ultrastructure; D002473:Cell Wall / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects* / Q000648:ultrastructure; D005578:Fosfomycin / Q000494:pharmacology*; D011523:Protoplasts / Q000648:ultrastructure; D012706:Serratia marcescens / Q000187:drug effects* / Q000648:ultrastructure; D013104:Spheroplasts / Q000302:isolation & purification* / Q000648:ultrastructure
chemical_list: D000900:Anti-Bacterial Agents; D005578:Fosfomycin