title: Association of HLA antigens with glucose intolerance following renal transplantation.
abstract: Records of 109 renal transplant patients were reviewed to test the hypothesis that post transplant glucose intolerance would be associated with "diabetic", HLA antigens (HLA--B8, B18, Bw15 and Bw16). Of 42 patients with significant glucose intolerance, 23 had one or more of these antigens (RR=2.65, P=0.01). These findings suggest that stress or drug treatment associated with renal transplantation can induce glucose intolerance in patients with a "diabetic" gene associated with the HLA--B locus.
mesh_terms: D002102:Cadaver; D003920:Diabetes Mellitus / Q000235:genetics*; D005947:Glucose / Q000378:metabolism*; D005951:Glucose Tolerance Test; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D016030:Kidney Transplantation; D012306:Risk; D014184:Transplantation, Homologous
chemical_list: D006680:HLA Antigens; D005947:Glucose