[In-patient treatment of peptic ulcer with cimetidine. II. Controlled double-blind trial on gastric ulcer patients (author's transl)].
In a controlled double-blind clinical trial of 39 in-patients with gastric ulcer the effect of cimetidine on ulcer healing, ulcer pain and pentagastrin-stimulated acid and pepsin secretion was measured. A faster healing rate in the cimetidine group was statistically not significant. Cimetidine had no effect on ulcer pain and pentagastrin-stimulated acid and pepsin secretion. There were no serious untoward reactions.
D000328:Adult; D000368:Aged; D002927:Cimetidine / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005745:Gastric Acidity Determination; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain; D010418:Pentagastrin; D010434:Pepsin A; D013276:Stomach Ulcer / Q000188:drug therapy*; D013997:Time Factors
D006146:Guanidines; D002927:Cimetidine; D010434:Pepsin A; D010418:Pentagastrin
Cimetidin in der stationären Behandlung des peptischen Ulkus. II. Doppelblindstudie bei Ulcus ventriculi.