title: The properdin system: composition and function.
abstract: This article summarized the physicohemical data on the factors which compose the properdin system in guinea pig and man. The following other topics are discussed: (1) Activation of the properdin system; (2) Formation of the initiating and amplification C3 convertases; (3) Formation of the C5 convertase, and (4) Regulatory control mechanisms of the properdin system.
mesh_terms: D000818:Animals; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003176:Complement C3; D050577:Complement C3-C5 Convertases; D003179:Complement C3b; D003182:Complement C5; D011415:Complement Factor B; D011416:Complement Factor D; D006168:Guinea Pigs; D006801:Humans; D011414:Properdin
chemical_list: D003176:Complement C3; D003182:Complement C5; D011414:Properdin; D003179:Complement C3b; D050577:Complement C3-C5 Convertases; C493488:CFD protein, human; D011416:Complement Factor D; D011415:Complement Factor B