Intrasellar paraganglioma associated with hypopituitarism.
A 37-year-old with a history of postpubertal arrest of sexual development and delayed growth was found to have an enlarged sella turcica. The clinical and biochemical features were consistent with hypopituitarism. A tumor was removed transsphenoidally that, through light microscopy, histochemistry, and electron microscopy, proved to be a paraganglioma. We report the possible origin of intrasellar paraganglioma, as well as the pathogenesis of hypopituitarism.
D000328:Adult; D006651:Histocytochemistry; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D007124:Immunoenzyme Techniques; D008297:Male; D010235:Paraganglioma / Q000150:complications* / Q000648:ultrastructure; D010908:Pituitary Hormones, Anterior / Q000032:analysis; D012658:Sella Turcica; D012888:Skull Neoplasms / Q000150:complications* / Q000648:ultrastructure
D010908:Pituitary Hormones, Anterior