[Role of substrates in providing energy for the secretory function of the stomach].
Glycogen, general lipids and free fatty acids (FFA) contents in mucosa of the dog stomach were studied at rest, in latency period, and at peak secretion induced by histamine or carbocholine. Histamine increased the glycogen and FFA contents in mucosa and decreased that of general lipids. Carbocholine reduced the glycogen content at peak secretion as compared with the latency period. The decrease in general lipids content was less obvious than that induced by histamine. The data obtained suggest that energy supply for acid and pepsin formation in the gastric mucosa depends on the substances applied; lipids are mainly used for HCl formation, and glycogen - for pepsinogen formation.
D000818:Animals; D002217:Carbachol / Q000494:pharmacology; D004285:Dogs; D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism*; D006003:Glycogen / Q000378:metabolism*; D006632:Histamine / Q000494:pharmacology; D050356:Lipid Metabolism; D010434:Pepsin A / Q000378:metabolism
D005230:Fatty Acids, Nonesterified; D006632:Histamine; D002217:Carbachol; D006003:Glycogen; D010434:Pepsin A
Rol' substratov v énergeticheskom obespechenii sekretornoĭ funktsii zheludka.