Effect of hyaluronidase on the incidence of cystoid macular edema.
A prospective double-blind study of the effect of hyaluronidase on aphakic cystoid macular edema (CME) was performed. A 25% incidence of CME was encountered in patients receiving hyaluronidase admixed with the local anesthetic while no cases were diagnosed in the group not receiving hyaluronidase. The role of hyaluronidase in the pathogenesis of aphakic cystoid macular edema is discussed.
D000109:Acetylcholine / Q000008:administration & dosage; D002387:Cataract Extraction / Q000379:methods; D002986:Clinical Trials as Topic; D003560:Cysts / Q000150:complications; D048909:Diabetes Complications; D004311:Double-Blind Method; D004487:Edema / Q000139:chemically induced* / Q000175:diagnosis; D004837:Epinephrine / Q000008:administration & dosage; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000009:adverse effects* / Q000494:pharmacology; D006973:Hypertension / Q000150:complications; D008266:Macula Lutea / Q000187:drug effects*; D011446:Prospective Studies; D012164:Retinal Diseases / Q000139:chemically induced*
D006821:Hyaluronoglucosaminidase; D000109:Acetylcholine; D004837:Epinephrine