Leukemic relapse 5 1/2 years after allogeneic bone marrow transplantation.
A 13-yr-old male with acute myelogenous leukemia was treated with various chemotherapy regimens for 3 1/2 yr and then underwent an allogeneic bone marrow transplantation. The donor marrow was successfully engrafted, and the patient remained in remission free of all chemotherapy. Then, 5 1/2 yr later, he developed an extramedullary relapse with a chloroma of his maxillary sinus. This case illustrates the need for prolonged followup of transplant recipients and suggest that statements proposing cure as a result of this procedure may be premature.
D000293:Adolescent; D016026:Bone Marrow Transplantation; D005500:Follow-Up Studies; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D008297:Male; D008443:Maxillary Sinus; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis; D012008:Recurrence; D012075:Remission, Spontaneous; D012852:Sinusitis / Q000175:diagnosis; D014184:Transplantation, Homologous