Metabolic activation of 3-methylcholanthrene and its metabolites to products mutagenic to bacterial and mammalian cells.
D000818:Animals; D001711:Biotransformation; D002478:Cells, Cultured; D003577:Cytochrome P-450 Enzyme System; D066298:In Vitro Techniques; D008297:Male; D008748:Methylcholanthrene / Q000031:analogs & derivatives* / Q000378:metabolism* / Q000494:pharmacology; D008862:Microsomes, Liver / Q000378:metabolism; D009153:Mutagens / Q000378:metabolism*; D010105:Oxygenases / Q000378:metabolism; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects
D009153:Mutagens; D008748:Methylcholanthrene; D003577:Cytochrome P-450 Enzyme System; D010105:Oxygenases