title: [Ultrastructure of Darier's disease].
abstract: Biopsies from four patients with Darier's disease were studied by electron microscopy. The desmosome-tonofilament complex does not seem to be primarily involved in the acantholytic process responsible for the epidermal cells separation with formation of suprabasal lacunae. Grains and corps ronds are consistent histopathological findings in Darier's disease: the ultrastructure of these cells is described.
mesh_terms: D007644:Darier Disease / Q000473:pathology*; D004817:Epidermis / Q000648:ultrastructure; D006801:Humans; D008854:Microscopy, Electron; D012867:Skin / Q000648:ultrastructure*
vernacular_title: Ultraestructura de la enfermedad de Darier.