The influence of extracts from the skeletal muscle of guinea-pigs infected with Myco bovis BCG-Praha and/or with Myco fortuitum on the viability of Ehrlich ascites tumor cells.
Description of results obtained by following the influence of muscle from guinea-pigs infected with Myco bovis BCG-Praha and/or Myco fortuitum on the viability of Ehrlich ascites tumor cells is presented. The muscle extracts were prepared from the striated muscles of the upper and lower extremities as well as the sternal muscle of guinea-pigs killed on the 1st, 15th, 35th and 70th days after infection with the above-mentioned mycobacterial strains. It follows from the results obtained that only muscle extracts from guinea-pigs infected with BCG-Praha will exhibit a considerable potential inhibiting the viability of Ehrlich ascites tumor cells. This inhibitory factory could not be eliminated from muscle extracts either through saturation by a homologous mycobacterial strain or by homogenates of striated muscles gained from healthy, non-infected guinea-pigs.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000473:pathology*; D002470:Cell Survival; D005260:Female; D006168:Guinea Pigs; D008297:Male; D051379:Mice; D009132:Muscles; D009164:Mycobacterium Infections / Q000378:metabolism*; D009163:Mycobacterium bovis; D014020:Tissue Extracts / Q000494:pharmacology*; D014376:Tuberculosis; D014774:Virulence
D014020:Tissue Extracts