title: Infections following clenched-fist injury: a new perspective.
abstract: Fifteen cases of clenched-fist injury were studied by aerobic, anaerobic, and 10% CO2 cultures. Anaerobic bacteria and Eikenella corrodens were prominent pathogens, being recovered in 60% and 20% of cases, respectively. These organisms are more susceptible to penicillin than to penicillinase-resistant penicillins or cephalosporins. All clenched-fist injuries should be cultured in aerobic, anaerobic, and 10% CO2 atmospheres. We recommend the use of both penicillin and a penicillinase-resistant penicillin as initial empiric therapy.
mesh_terms: D001431:Bacteriological Techniques; D001442:Bacteroides Infections / Q000188:drug therapy / Q000209:etiology*; D016124:Eikenella corrodens / Q000302:isolation & purification; D006230:Hand Injuries / Q000150:complications* / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010406:Penicillins / Q000627:therapeutic use
chemical_list: D010406:Penicillins