[The beneficial role of blood transfusion and preganancy in the survival of renal allografts].
This analysis involves 93 cases of transplants of non-related cadaver kidneys. The result was better (p = 0.02 at 1 year) in recipients transfused before the graft (73 cases) than in those who had not been trasfused (20 cases). However, this latter group had a shorter average period of haemodialysis (p = 0.05 than the first. The benefits of pre-immunisation appear from 1 to 2 transfusions or 1 pregnancy onwards (p = 0.02 at 1 year). Subjects transfused during the 6 months prior to the transplant had a graft which was functional more often than those who had been more than 6 months before the operation (p = 0.01 at 6 months). These results would be in favour of routine small quantity transfusions, approximately every six months in patients undergoing haemodialysis and on a waiting list for transplantation.
D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000032:analysis; D001803:Blood Transfusion; D002102:Cadaver; D002648:Child; D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D006085:Graft Survival; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D016030:Kidney Transplantation; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D013997:Time Factors; D014181:Transplantation Immunology; D014184:Transplantation, Homologous
D000906:Antibodies; D006680:HLA Antigens
Rôle bénéfique des transfusions sanguines et des grossesses dans la survie des allogreffes rénales.