In vivo formation of N-nitroso compounds and detection of their mutagenic activity in the host-mediated assay.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005753:Gastric Mucosa / Q000378:metabolism*; D008297:Male; D008782:Methylurea Compounds / Q000494:pharmacology; D051379:Mice; D009153:Mutagens; D009573:Nitrites / Q000494:pharmacology; D009602:Nitrosamines / Q000378:metabolism / Q000494:pharmacology; D009603:Nitroso Compounds / Q000378:metabolism* / Q000494:pharmacology; D012486:Salmonella typhimurium / Q000187:drug effects*; D013329:Structure-Activity Relationship
D008782:Methylurea Compounds; D009153:Mutagens; D009573:Nitrites; D009602:Nitrosamines; D009603:Nitroso Compounds