title: Psychiatric illness and human renal transplantation.
abstract: This study focuses on physiological as well as psychological causes for psychiatric illness in renal transplant recipients. During an 18 month period 20 transplant recipients were evaluated in psychiatric consultation. A variety of psychiatric illnesses were noted with eight having a secondary depression diagnosed according to psychiatric research criteria. Case histories of these patients indicated that corticosteroid and meythyldopa therapy were significant etiologic agents in the development of the depressive syndrome. A step-wise approach to the management of patients with depressed mood or slowed thinking was proposed.
mesh_terms: D000275:Adjustment Disorders / Q000209:etiology; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D002102:Cadaver; D003863:Depression / Q000139:chemically induced / Q000209:etiology*; D005260:Female; D006084:Graft Rejection / Q000187:drug effects; D006801:Humans; D006977:Hypertension, Renal / Q000188:drug therapy; D016030:Kidney Transplantation; D008297:Male; D008750:Methyldopa / Q000627:therapeutic use; D019965:Neurocognitive Disorders / Q000209:etiology; D011183:Postoperative Complications / Q000188:drug therapy / Q000209:etiology*; D014184:Transplantation, Homologous
chemical_list: D000305:Adrenal Cortex Hormones; D008750:Methyldopa