Clinical syndromes of myasthenia in infancy and childhood. A review.
Ten clinical syndromes of defective neuromuscular transmission in infancy and childhood are reviewed. Autoimmune, genetic, infectious, and pharmacologic mechanisms have been implicated. These disorders manifest themselves in a variety of ways including severe respiratory insufficiency. Prompt diagnosis and treatment may be lifesaving.
D000110:Acetylcholinesterase / Q000172:deficiency; D000367:Age Factors; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D001906:Botulism / Q000150:complications; D001932:Brain Neoplasms / Q000150:complications; D002648:Child; D002675:Child, Preschool; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D003095:Collagen Diseases / Q000150:complications; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000503:physiopathology; D008297:Male; D009157:Myasthenia Gravis / Q000503:physiopathology / Q000628:therapy; D011247:Pregnancy; D012737:Sex Factors; D013577:Syndrome
D000900:Anti-Bacterial Agents; D002800:Cholinesterase Inhibitors; D000110:Acetylcholinesterase