title: The surface morphology of mitogen-stimulated human peripheral blood lymphocytes.
abstract: The changes occurring in surface morphology during the transformation of normal peripheral blood lymphocytes by phytohaemagglutinin (PHA) are described and the surface ultrastructure of the PHA-induced blasts is compared with that of pokeweed mitogen (PWM)-and rabbit anti-beta2-microglobulin antiserum-induced blasts. Both mitogen-specific and non-specific changes were observed and their possible relationship to the activation of lymphocyte subpopulations is discussed. Similar surface characteristics found in various tissue lymphoid cells are also described.
mesh_terms: D000888:Antibodies, Anti-Idiotypic; D002462:Cell Membrane / Q000648:ultrastructure; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000648:ultrastructure*; D008855:Microscopy, Electron, Scanning; D008934:Mitogens; D013997:Time Factors; D001613:beta 2-Microglobulin / Q000276:immunology
chemical_list: D000888:Antibodies, Anti-Idiotypic; D008934:Mitogens; D001613:beta 2-Microglobulin