Experimental and clinical experiences with long-term kidney preservation by use of simpel hypothermia.
In an experimental work published in 1973, it was found, that it was possible to preserve pig kidneys with up to one hour of warm ischemia for 24 hours using pretreatment with chlorpromazine and subsequent preservation with simpel hypothermia (Collings C2-solution). Clinical experiences with this method are now presented and confirm, that this method allows preservation of ischaemic damaged kidneys for about 24 hours.
D000818:Animals; D002746:Chlorpromazine / Q000494:pharmacology; D005069:Evaluation Studies as Topic; D006801:Humans; D007036:Hypothermia, Induced; D007668:Kidney / Q000187:drug effects; D016030:Kidney Transplantation; D009926:Organ Preservation; D013997:Time Factors; D014019:Tissue Donors; D014021:Tissue Preservation; D014184:Transplantation, Homologous
D002746:Chlorpromazine