title: Replacement of ruptured chordae tendineae of the mitral valve with autologous pericardial chordae.
abstract: Severe mitral regurgitation owing to rupture of chordae tendineae has been repaired in 10 patients by construction of new chordae from autologous pericardium. The site of rupture was the posterior leaflet in eight patients, the anterior leaflet in one patient, and both leaflets in one patient. Cardiac catheterization demonstrated severe mitral regurgitation (average 49%) and a left atrial V wave of 45 mm. Hg. The reconstruction was carried out with pericardium rolled into a chorda with one end attached to the appropriate papillary muscle and the other attached to the flail edge of the mitral valve leaflet being repaired. One patient died on the seventh postoperative day from pneumonia. The remaining nine patients are alive and well (Functional Class I) from 6 months to 9 1/2 years (average 3 years) following the operation. None requires anticoagulants.
mesh_terms: D000368:Aged; D000790:Angiocardiography; D001794:Blood Pressure; D006328:Cardiac Catheterization; D002815:Chordae Tendineae; D005260:Female; D005500:Follow-Up Studies; D006341:Heart Rupture / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D010496:Pericardium / Q000637:transplantation*; D011652:Pulmonary Circulation; D013536:Suture Techniques; D014182:Transplantation, Autologous