Trasylol (aprotinin) and kidney preservation.
Experiments carried out in rats and sheep have shown that Trasylol (aprotinin) is helpful in protecting kidneys from the harmful effects of ischaemia. After critical periods of ischaemia, renal failure was less frequent in the treated groups, and glomerular leakage of 131I-labelled albumin was greatly reduced.
D058186:Acute Kidney Injury / Q000517:prevention & control*; D000818:Animals; D007611:Aprotinin / Q000494:pharmacology*; D006085:Graft Survival; D007511:Ischemia / Q000150:complications / Q000503:physiopathology; D007668:Kidney / Q000098:blood supply / Q000503:physiopathology; D016030:Kidney Transplantation; D007683:Kidney Tubular Necrosis, Acute / Q000209:etiology / Q000517:prevention & control*; D009926:Organ Preservation; D051381:Rats; D012756:Sheep; D014021:Tissue Preservation
D007611:Aprotinin