Structural requirements for the metabolic activation of benzo[a]pyrene to mutagenic products: effects of modifications in the 4,5-, 7,8-, and 9,10-positions.
D000818:Animals; D001580:Benzopyrenes / Q000138:chemical synthesis / Q000378:metabolism* / Q000494:pharmacology; D004851:Epoxide Hydrolases / Q000378:metabolism; D008862:Microsomes, Liver / Q000201:enzymology; D009153:Mutagens / Q000378:metabolism*; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D001580:Benzopyrenes; D009153:Mutagens; D004851:Epoxide Hydrolases