The role of HLA-DR antigens in transplantation--survival of skin allografts in HLA-haploidentical donor-recipient combinations.
The results of 79 skin grafts performed in haploidentical donor-recipient pairs are correlated with HLA-A, -B, -C, and -DR compatibility. A strong detrimental effect of DR incompatibilities has been demonstrated. This effect is independent from that exerted by products of the HLA-A, -B, and -C loci. An additive effect of HLA-A, -B, and -DR incompatibilities on allograft survival time has been observed.
D002874:Chromosome Mapping; D005260:Female; D006085:Graft Survival; D006680:HLA Antigens / Q000276:immunology*; D006238:Haploidy; D006801:Humans; D008297:Male; D016038:Skin Transplantation; D014184:Transplantation, Homologous
D006680:HLA Antigens