Glomerulonephritis in dermatitis herpetiformis. A case study.
A patient with dermatitis herpetiformis, proteinuria and reduced renal function is described. A renal biopsy studied by light and immunofluorescence microscopy revealed a glomerulonephritis with deposits of predominantly IgA and complement C3. Deposits of IgA and C3 were also demonstrated in a biopsy from normal skin, and a common pathway for the skin and renal lesions is suggested.
D003176:Complement C3 / Q000032:analysis; D003874:Dermatitis Herpetiformis / Q000150:complications*; D005260:Female; D005455:Fluorescent Antibody Technique; D005921:Glomerulonephritis / Q000150:complications*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007668:Kidney / Q000473:pathology; D007678:Kidney Glomerulus / Q000276:immunology; D008875:Middle Aged; D012867:Skin / Q000473:pathology
D003176:Complement C3; D007070:Immunoglobulin A