125 I-anti-immunoglobulin test: a new tool for the detection of drug-allergic platelet antibodies.
It is shown that the 125I-anti-immunoglobulin test with platelets is as sensitive and reproducible for the detection of quinidine-associated antibodies as platelet complement fixation. Because of its independence from complement activation, this test might prove most valuable for the demonstration of non-complement-fixing, drug-associated antibodies.
D000906:Antibodies / Q000302:isolation & purification*; D001792:Blood Platelets / Q000276:immunology*; D003168:Complement Fixation Tests; D006801:Humans; D007158:Immunologic Techniques; D011696:Purpura, Thrombocytopenic / Q000276:immunology; D011802:Quinidine / Q000276:immunology*; D011863:Radioimmunoassay
D000906:Antibodies; D011802:Quinidine