Protection against challenge with Escherichia coli heat-labile enterotoxin by immunization of rats with cholera toxin/toxoid.
Rats were used to study dose-response curves to intestinal challenge with cholera toxin or Escherichia coli heat-labile enterotoxin. Prior immunization with cholera toxin/toxoid induced significant and equal protection against both toxins.
D000818:Animals; D000992:Antitoxins; D001427:Bacterial Toxins / Q000037:antagonists & inhibitors*; D002772:Cholera Toxin / Q000037:antagonists & inhibitors; D004305:Dose-Response Relationship, Drug; D004768:Enterotoxins / Q000037:antagonists & inhibitors*; D004926:Escherichia coli; D005260:Female; D007082:Ileum / Q000187:drug effects; D007114:Immunization; D051381:Rats; D014121:Toxoids
D000992:Antitoxins; D001427:Bacterial Toxins; D004768:Enterotoxins; D014121:Toxoids; D002772:Cholera Toxin