[Analysis of immune reactions of the CSF. A neuro-immunologic classification (author's transl)].
CSF immunological reactions are classified in 5 patterns, considering the level of CSF albumin and the percentage of CSF-IgG. The 5 patterns are: 1) normal, 2) inflammatory (pure local synthesis of IgG), 3) two types of trasudates (inflammatory or not) when blood-CSF exchanges increase, 4) meningitis if a transudate is associated with local IgG synthesis. The distinction between transudate and meningitis needs the determination of serum IgG. This classification better than the classical ratios, defines the immunological status of a neurological patient in the different phases of his disease. It determines the frequency of the 5 immunological patterns for each nervous disease and the signification of any antibody detected in the CSF. It proposes a common language between the different laboratories and overall, between biologists and clinicians.
D000418:Albumins / Q000134:cerebrospinal fluid; D001927:Brain Diseases / Q000134:cerebrospinal fluid / Q000276:immunology; D002555:Cerebrospinal Fluid / Q000276:immunology*; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis / Q000276:immunology; D005122:Exudates and Transudates / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid*; D007249:Inflammation / Q000134:cerebrospinal fluid / Q000276:immunology; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000276:immunology
D000418:Albumins; D002556:Cerebrospinal Fluid Proteins; D007074:Immunoglobulin G
L'analyse des réactions immunitaires du liquide céphalo-rachidien. Un essai de classification neuro-immunologique.