Optimal perfusion parameters in kidney preservation.
The optimal pressure in the renal artery during initial perfusion with Collins' solution by spontaneous pressure in canine kidneys is 40-50 cm H2O and in human kidneys 40-60 cm H2O. An average-sized human kidney can be perfused by a full current which is limited only by the lumen of the infusion set. In smaller than average-sized human kidneys the current must be reduced to diminish the pressure in the renal artery to the optimal value. In prolonged hypothermal perfusion by means of a Gambro apparatus it will be necessary to assess the optimal pressure by direct measurement in the renal artery in intact average-sized human kidneys because the pressure reading on the manometer is not identical with the optimal pressure in the renal artery.
D000818:Animals; D001794:Blood Pressure; D004285:Dogs; D007668:Kidney / Q000033:anatomy & histology; D016030:Kidney Transplantation; D009926:Organ Preservation; D010477:Perfusion / Q000379:methods*; D012077:Renal Artery; D013696:Temperature; D014021:Tissue Preservation; D014184:Transplantation, Homologous