Relationship between 3,4-dihydroxyphenylacetaldehyde levels and tetrahydropapaveroline formation.
It was demonstrated that DOPAL, the aldehyde derived from the action of MAO on dopamine, can condense with dopamine to form THP. This compound is of special interest, since it is an intermediate in the biosynthesis of morphine.
D000079:Acetaldehyde / Q000031:analogs & derivatives* / Q000032:analysis / Q000378:metabolism*; D000437:Alcoholism / Q000378:metabolism*; D000818:Animals; D001923:Brain Chemistry; D004298:Dopamine / Q000032:analysis / Q000378:metabolism; D006801:Humans; D008995:Monoamine Oxidase / Q000494:pharmacology; D010208:Papaverine / Q000031:analogs & derivatives*; D051381:Rats; D013765:Tetrahydropapaveroline / Q000032:analysis / Q000096:biosynthesis*
D013765:Tetrahydropapaveroline; D010208:Papaverine; D008995:Monoamine Oxidase; D000079:Acetaldehyde; D004298:Dopamine