Treatment of multiple intestinal helminthiasis with oxantel and pyrantel.
32 elementary school children were treated for multiple intestinal helminthiasis (ascariasis, trichuriasis and hookworm infections) with a combination of the pamoate salts of oxantel and pyrantel in a dose of 15 to 20mg/kg body weight of each in 1 daily dose for 3 consecutive days. The cure rate for ascariasis was 96.7%, and 84.4% for both trichuriasis and hookworm infections. 68.7% were completely cured of all 3 helminths. However, among those not completely cured, only 1 species of the previous 3 infecting helminths was present after treatment and then with a very marked reduction in egg count.
D002648:Child; D002986:Clinical Trials as Topic; D004338:Drug Combinations; D006373:Helminthiasis / Q000188:drug therapy* / Q000469:parasitology; D006801:Humans; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy* / Q000469:parasitology; D011715:Pyrantel / Q000009:adverse effects / Q000627:therapeutic use*; D011743:Pyrimidines / Q000627:therapeutic use*; D013343:Styrenes / Q000627:therapeutic use
D004338:Drug Combinations; D011743:Pyrimidines; D013343:Styrenes; D011715:Pyrantel