title: [Pharmacokinetic characteristics and the effectiveness of using carbenicillin on newborn premature infants with infectious and inflammatory diseases].
abstract: The results of the study on the pharmacokinetics peculiar properties of carbenicillin premature infants treated with the drug administered intravenously or intramuscularly are presented. The maximum antibiotic blood levels after intravenous administration exceeded the MIC for most of the causative agents isolated from the children. The schemes for the antibiotic use in treatment of purulent septic processes of children are recommended.
mesh_terms: D000367:Age Factors; D001702:Biopharmaceutics; D001724:Birth Weight; D002228:Carbenicillin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000188:drug therapy*; D007700:Kinetics; D011014:Pneumonia / Q000188:drug therapy; D018805:Sepsis / Q000188:drug therapy
chemical_list: D002228:Carbenicillin
vernacular_title: Osobennosti farmakokinetiki i éffektivnost' primeneniia karbenitsillina u novorozhdennykh nedonoshennykh deteĭ s infektsionno-vospalitel'nymi zabolevaniiami.