title: [Mutagenic effect of new chemical compounds. IV. Mutagenic effect of dialkylaminoethyl esters of 5,6-dihydro-7H-benz(c)carbazol-carboxylic acids].
abstract: The mutagenic effect of dialkylaminoet hyl esters of 5,6-dihydro-7H-benz(c)carbazole-carboxylic acids on biochemical mutants (Escherichia coli P-678, Actinomyces rimosus 222) is found. Hydrochloride of diethylaminoethyl ester of 5,6-dihydro-7H-benz(c)carbazole-9-carboxylic acid, which induced reversible and direct mutations, proved to be the most active compound, its mutagenic activity exceeding considerably the activity of ethylene imine.
mesh_terms: D001388:Aziridines / Q000633:toxicity; D002227:Carbazoles / Q000633:toxicity*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics; D009153:Mutagens; D013045:Species Specificity; D013302:Streptomyces / Q000187:drug effects / Q000235:genetics
chemical_list: D001388:Aziridines; D002227:Carbazoles; D009153:Mutagens
vernacular_title: Mutagennoe deĭstvie novykh khimicheskikh soedineniĭ. Soobshchenie IV. Mutagennoe deĭstvie dialkilaminoétilovykh éfirov 5,6-digidro-7H-benz(c)karbazol-karbonovykh kislot.