title: t-Alleles and the possibility of post-meiotic gene expression during mammalian spermatogenesis.
abstract: Although there is strong evidence for post-meiotic RNA synthesis during spermatogenesis, definitive proof of haploid gene transcription is lacking. Segregation distortion in t-allele-bearing males provides evidence for post-meiotic gene expression since delayed mating experiments argue strongly that there are similar numbers of qualitatively different spermatozoa in ejaculates of males carrying moderately distorting t-alleles. Such post-meiotic transcription may not be infrequent but the intercellular bridges connecting spermatids would usually maintain gametic equivalence.
mesh_terms: D000483:Alleles; D000818:Animals; D005260:Female; D005796:Genes; D007365:Intercellular Junctions / Q000502:physiology; D008297:Male; D008540:Meiosis; D051379:Mice; D010641:Phenotype; D012313:RNA / Q000096:biosynthesis; D013091:Spermatogenesis; D013094:Spermatozoa / Q000502:physiology; D013997:Time Factors
chemical_list: D012313:RNA