title: [Differential indications for desipramine--results of a controlled multiclinical study].
abstract: The antidepressants desipramine and imipramine were compared within the framework of a multiclinical study performed under the conditions of a controlled clinical experiment. There has been found a time-different remission of affective symptoms, which was not detectable for the inhibition of drive. The tachythymoleptic action of desipramine is discussed with reference to these results. Evaluation of the possibility of controlling affects shows different ranges of activity of desipramine and imipramine, with desipramine influencing especially negative psychoenergetic symptoms in the area of drives and emotions and imipramine, restrictive symptoms in addition to differential phenomena of the psychomotor expression.
mesh_terms: D002986:Clinical Trials as Topic; D003863:Depression / Q000175:diagnosis / Q000188:drug therapy*; D003891:Desipramine / Q000627:therapeutic use*; D004311:Double-Blind Method; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use
chemical_list: D007099:Imipramine; D003891:Desipramine
vernacular_title: Zur Differentialindikation von Desipramin--Ergebnisse einer kontrollierten multiklinischen Studie.