title: Gastric secretory function in coeliac disease.
abstract: Volume, total titrable acidity, total proteolytic activity and pepsin activity have been determined in 14 coeliac patients and in 8 controls of comparable ages and body weights. Basal secretion (B.O.), total outputs (T. O.) and peak outputs (P.O.) after pentagastrin injection have been determined. Peak outputs (values 60 min/kg) of these parameters are as follows: volume 5.0+/-1.7 ml in coeliacs, 4.3+/-1.2 ml in controls; total titrable acidity 406.1+/-155.0 mEq in patients, 296.1+/-182.4 in conttrols; total proteolytic activity 962.1+/-501.1 micronEq in coeliacs, 569.6+/-272.2 in controls; pepsin activity 789.1+/-521.8 micronEq in patients, 447.6+/-150.4 in controls.
mesh_terms: D002446:Celiac Disease / Q000175:diagnosis*; D005260:Female; D005745:Gastric Acidity Determination; D005750:Gastric Juice / Q000032:analysis*; D006801:Humans; D007223:Infant; D008297:Male; D010434:Pepsin A / Q000032:analysis; D010447:Peptide Hydrolases / Q000032:analysis
chemical_list: D010447:Peptide Hydrolases; D010434:Pepsin A