title: Myocardial revascularization: a rebuttal of the cooperative study.
abstract: From January 1972 through December 1974, at Saint Louis University Medical Center (SLU), 345 patients similar to those of the VA Cooperative Coronary Artery Study received CABG. Operative mortality was SLU 2.3%, VA 5.6% (p < 0.05). Perioperative myocardial infarction rate was SLU 8.4%, VA 18% (p < 0.005). One year graft patency was SLU 87%, VA 71%; all grafts patent SLU 76%, VA 54%; at least one graft patent SLU 96%, VA 89%. SLU angina pectoris relief at five years was 90%. SLU patients free of myocardial infarction five years postoperatively was 83%. Comparative cumulative four year survivals were: [Table: see text] Cumulative four-year survival in 272 SLU patients (79%) completely revascularized was 94%, compared to SLU entire group of 95%, VA medical 86% (p < 0.002) and VA surgical 85% (p < 0.002). Comparing 1972-74 SLU results to VA medical and surgical groups, CABG prolonged life in patients with double and triple vessel disease and in those completely revascularized.
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000517:prevention & control; D001026:Coronary Artery Bypass / Q000401:mortality; D005069:Evaluation Studies as Topic; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D008923:Missouri; D009203:Myocardial Infarction / Q000209:etiology / Q000517:prevention & control; D011183:Postoperative Complications / Q000401:mortality; D014182:Transplantation, Autologous; D014481:United States; D014493:United States Department of Veterans Affairs; D014680:Veins / Q000637:transplantation