Endothelial monocyte antigens in man.
A group of antigens expressed in endothelial cells and monocytes, but not detectable in either T or B lymphocytes, has been the object of ongoing studies. The antibodies were not removed by absorption with platelets or B lymphocytes and were readily eliminated after absorption with monocytes or endothelial cells. Stripping with rabbit anti-human beta2-microglobulin made endothelial cells or monocytes resistant to lysis by endothelial-monocyte antibodies. Thus, endothelial monocyte antigens may be associated with beta2-microglobulin and are distinct from HLA-DR in this regard. Family studies suggest that most, but not all, monocyte-specific reactions segregated in linkage with HLA.
D000941:Antigens; D001402:B-Lymphocytes / Q000276:immunology; D004727:Endothelium / Q000276:immunology; D005260:Female; D006680:HLA Antigens / Q000235:genetics; D006650:Histocompatibility Testing; D006801:Humans; D009000:Monocytes / Q000276:immunology*; D011247:Pregnancy; D014470:Umbilical Cord / Q000276:immunology; D001613:beta 2-Microglobulin / Q000276:immunology
D000941:Antigens; D006680:HLA Antigens; D001613:beta 2-Microglobulin