[Bronchial mucociliary clearance in chronic bronchitics (author's transl)].
Bronchial mucociliary clearance is analysed in 13 clinically stable patients with chronic bronchitis in comparison with 7 normal non smokers by measuring the rate of removal of inhaled monodispersed particles of resin (diameter: 8.1 +/- 3.5 micrometer) tagged with 99mTc. Particles delivered with a high insufflation rate are uniformly deposited on proximal airways. The pattern of distribution is comparable in all the subjects studied. In normal non smokers, the percentage of bronchial radioactivity cleared 1 h after the inhalation was 34 +/- 11.2 percent. The patients may be divided into 2 groups: Group 1 (n = 6) is characterized by a  mucociliary clearance similar to the normals while group 2 (n = 7) shows a low mucociliary transport rate (decrease of bronchial radioactivity after 4 h less than 10 percent).
D000328:Adult; D000368:Aged; D001980:Bronchi / Q000503:physiopathology*; D001991:Bronchitis / Q000503:physiopathology*; D002908:Chronic Disease; D002923:Cilia / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000503:physiopathology; D012116:Resins, Plant; D013667:Technetium; D014132:Trachea / Q000503:physiopathology*
D012116:Resins, Plant; D013667:Technetium
Mesure de la clearance muco-ciliaire des bronches proximales chez le bronchitique chronique.