title: Chronic laxative abuse associated with pancreatic islet cell hyperplasia.
abstract: Marked pancreatic islet cell hyperplasia was found in a patient with laxative-induced diarrhoea. It is suggested that laxative abuse might be an important aetiological factor in patients with pancreatic islet cell hyperplasia and the watery diarrhoea syndrome but in whom no hormonal excess can be demonstrated.
mesh_terms: D000328:Adult; D002400:Cathartics / Q000506:poisoning*; D003967:Diarrhea / Q000139:chemically induced; D006801:Humans; D006965:Hyperplasia / Q000139:chemically induced; D007515:Islets of Langerhans / Q000473:pathology*; D008297:Male; D019966:Substance-Related Disorders
chemical_list: D002400:Cathartics