Possible presence of autoantibodies to zone pellucida in infertile women.
Of 52 serum samples from infertile women tested against isolated porcine oocytes by immunofluorescence, 8 produced intense reactions in zonae pellucidae, while only one of 52 sera from control subjects showed the reaction. Autoantibodies to the zona may be present in these women.
D000818:Animals; D001323:Autoantibodies; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007247:Infertility, Female / Q000276:immunology*; D009865:Oocytes / Q000276:immunology; D010063:Ovum / Q000276:immunology*; D013552:Swine / Q000276:immunology; D015044:Zona Pellucida / Q000276:immunology*
D001323:Autoantibodies