title: The assessment of interaction between drugs by the Autobac 1 system.
abstract: A study has been undertaken on the applicability of the Autobac 1 system to the checker board method to determine the interaction of combined drugs on bacterial populations. Preliminary results are reported which show that the Autobac makes easier, accurate, flexible and rapid such a method. In order to improve the significance and facilitate technical operations and data processing of this test additional equipment and device are suggested.
mesh_terms: D002505:Cephacetrile / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D003091:Colistin / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004917:Erythromycin / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D005839:Gentamicins / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009268:Nalidixic Acid / Q000494:pharmacology; D009582:Nitrofurantoin / Q000494:pharmacology; D012293:Rifampin / Q000494:pharmacology; D013754:Tetracyclines / Q000494:pharmacology
chemical_list: D004338:Drug Combinations; D005839:Gentamicins; D013754:Tetracyclines; D009268:Nalidixic Acid; D004917:Erythromycin; D002701:Chloramphenicol; D009582:Nitrofurantoin; D002505:Cephacetrile; D012293:Rifampin; D003091:Colistin