[In vitro activity of cefoxitin compared with the activity of other antibiotics and trimethoprim-sulfamethoxazole (author's transl)].
The new developed antibiotic cefoxitin has been tested in vitro on its effectiveness against bacteria isolated from human material. Pseudomonas aeruginosa and streptococci of the serological group D were not tested, because these microorganisms are not sensitive against this antibiotic. Besides cefoxitin other antibiotics (cephalothin, cephalexin, ampicillin, carbenicillin, tetracycline, gentamicin, penicillin G, oxacillin) and trimethoprim-sulfamethoxazole were also tested. As to the results cefoxitin shows the best effectiveness against all gram-positive bacteria and against gram-negative bacteria including indol-positive species of proteus, providencia, serratia marcescens and the anaerobe, gram-negative, non-spore-forming rods. There are different results with enterobacter-, citrobacter-, achromobacter- and acinetobacter-species.
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001431:Bacteriological Techniques; D002440:Cefoxitin / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology*; D006089:Gram-Negative Anaerobic Bacteria / Q000187:drug effects; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D013420:Sulfamethoxazole / Q000494:pharmacology*; D014295:Trimethoprim / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D002440:Cefoxitin; D014295:Trimethoprim; D013420:Sulfamethoxazole
In-vitro-Aktivität von Cefoxitin-Natrium im Vergleich mit anderen Antibiotika und Trimethoprim-Sulfamethoxazol.