Vitamin A deficiency following small-bowel bypass surgery for obesity.
Side effects are common in individuals who have undergone small-bowel bypass surgery for morbid obesity. Most of these side effects subside after a few months. More serious complications may require reestablishment of the bypassed loop. Rarely have vitamin deficiencies been observed. Development of vitamin A deficiency in a patient was characterized by phrynoderma and night blindness. This was promptly reversed by oral treatment with vitamin A. There was no improvement in low to subnormal serum levels of fat-soluble vitamins after a course of tetracycline hydrochloride. Studies suggested presence of a malabsorption state probably due to rapid transit time through the small bowel and reduced absorptive surface.
D000293:Adolescent; D005260:Female; D006801:Humans; D007082:Ileum / Q000601:surgery*; D007583:Jejunum / Q000601:surgery*; D008286:Malabsorption Syndromes / Q000209:etiology; D009755:Night Blindness / Q000188:drug therapy / Q000209:etiology; D009765:Obesity / Q000628:therapy*; D011183:Postoperative Complications; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy / Q000209:etiology; D013754:Tetracyclines / Q000627:therapeutic use; D014801:Vitamin A / Q000627:therapeutic use; D014802:Vitamin A Deficiency / Q000150:complications / Q000188:drug therapy / Q000209:etiology*
D013754:Tetracyclines; D014801:Vitamin A