title: The relationship between carcinogenicity and mutagenicity of some polynuclear hydrocarbons.
abstract: 25 polynuclear hydrocarbons were tested for mutagenicity using the Ames Assay and the results were compared with existing carcinogenicity data. The assessment of the predictive value of this particular short-term test showed a 58% positive and a 41% negative correlation.
mesh_terms: D001551:Benz(a)Anthracenes / Q000494:pharmacology*; D001580:Benzopyrenes / Q000494:pharmacology*; D002273:Carcinogens; D004305:Dose-Response Relationship, Drug; D005821:Genetic Techniques; D009153:Mutagens; D012486:Salmonella typhimurium
chemical_list: D001551:Benz(a)Anthracenes; D001580:Benzopyrenes; D002273:Carcinogens; D009153:Mutagens