Defective neutrophil chemotaxis and hyperimmunoglobulinemia E in a child with recurrent infections.
The clinical and immunologic features of an adolescent boy with recurrent pyogenic infections are presented. A cellular defect in neutrophil chemotaxis, hyperimmunoglobulinemia E, and a negative delayed cutaneous reaction to antigen from Candida albicans were found.
D000293:Adolescent; D000946:Antigens, Fungal; D001424:Bacterial Infections / Q000276:immunology*; D002176:Candida albicans / Q000276:immunology; D002634:Chemotaxis, Leukocyte; D006801:Humans; D006942:Hypergammaglobulinemia / Q000276:immunology*; D006968:Hypersensitivity, Delayed; D007073:Immunoglobulin E; D008297:Male; D009504:Neutrophils / Q000276:immunology*; D012008:Recurrence; D012882:Skin Tests
D000946:Antigens, Fungal; D007073:Immunoglobulin E