title: Apurinic endonucleases from Saccharomyces cerevisiae.
abstract: Three endonuclease activities have been partially purified from Saccharomyces cerevisiae on the basis of their activity against x-irradiated closed-circular supercoiled bacteriophage PM2 DNA. These endonucleases also nick apurinic DNA and two out of the three activities incise DNA UV-irradiated with high doses. The endonuclease activities have also been distinguished on the basis of their magnesium requirement and sensitivity to EDTA.
mesh_terms: D001080:Apurinic Acid; D003851:Deoxyribonucleases / Q000302:isolation & purification*; D004720:Endonucleases / Q000302:isolation & purification*; D012441:Saccharomyces cerevisiae / Q000201:enzymology*; D013379:Substrate Specificity
chemical_list: D001080:Apurinic Acid; D003851:Deoxyribonucleases; D004720:Endonucleases