Covalent intercalative binding to DNA in relation to the mutagenicity of hydrocarbon epoxides and N-acetoxy-2-acetylaminofluorene.
D000099:Acetoxyacetylaminofluorene / Q000378:metabolism* / Q000494:pharmacology; D004278:DNA, Superhelical / Q000378:metabolism*; D004279:DNA, Viral / Q000378:metabolism*; D004852:Epoxy Compounds / Q000378:metabolism* / Q000494:pharmacology; D004988:Ethers, Cyclic / Q000378:metabolism*; D005449:Fluorenes / Q000378:metabolism*; D006868:Hydrolysis; D008854:Microscopy, Electron; D008956:Models, Chemical; D009153:Mutagens; D009690:Nucleic Acid Conformation / Q000187:drug effects; D011083:Polycyclic Compounds / Q000378:metabolism* / Q000494:pharmacology; D012486:Salmonella typhimurium / Q000187:drug effects; D013343:Styrenes / Q000378:metabolism / Q000494:pharmacology
D004278:DNA, Superhelical; D004279:DNA, Viral; D004852:Epoxy Compounds; D004988:Ethers, Cyclic; D005449:Fluorenes; D009153:Mutagens; D011083:Polycyclic Compounds; D013343:Styrenes; D000099:Acetoxyacetylaminofluorene