title: Gamma variate analysis of pulmonary dilution curves for quantitation of left-to-right cardiac shunts.
abstract: Left-to-right shunts were quantified in patients with atrial septal defect using a gamma variate least square fit to radionuclide pulmonary dilution curves. All patients were studied with cardiac catheterization. There was a close correlation between the Fp/Fs ratios obtained by oximetry in cardiac catheterization and by gamma variate analysis. The results suggest that the radionuclide dilution method is sufficiently reliable to be used as a screening tests for the detection and quantitation of left-to-right cardiac shunts.
mesh_terms: D000293:Adolescent; D000328:Adult; D006328:Cardiac Catheterization; D006344:Heart Septal Defects, Atrial / Q000000981:diagnostic imaging*; D006801:Humans; D008722:Methods; D008875:Middle Aged; D010092:Oximetry; D011865:Radioisotope Dilution Technique; D011877:Radionuclide Imaging