[Insulin-forming activity of monolayer cultures of pancreatic islet cells from cattle fetuses].
The radioimmunological method was applied to the study of insulin content in the growth medium of primary monolayer cultures of bovine fetal pancreatic islet cells grown with usual and increased (300 mg%) glucose content. The latter led to an enhanced insulin secretion. The results of cytological study demonstrated a definite interrelationship between the mitotic activity of culture cells and the intensity of insulin secretion into the medium.
D000818:Animals; D002417:Cattle; D002478:Cells, Cultured; D005947:Glucose / Q000494:pharmacology; D007328:Insulin / Q000096:biosynthesis* / Q000378:metabolism; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000166:cytology / Q000378:metabolism*; D013997:Time Factors
D007328:Insulin; D005947:Glucose
Insulinoobrazuiushchaia aktivnost' odnosloĭnykh kul'tur ostrovkovykh kletok podzheludochnoĭ zhelezy plodov krupnogo rogatogo skota.