title: [Problems of bacteriologic diagnosis and aimed antibiotic therapy in pyogenic maxillofacial infections].
abstract: Bacteriologic analysis of pathogens from pyogenic infections of the jaw in 71 patients revealed that bacteria normally found in the buccal cavity predominated in 86% of the specimens. Considering the fact that no pathogens could be identified in 7% of the specimens, this then means that pathogens were only found in 7% of the specimens. Six to 12 strains were usually isolated in the mixed bacteria population of the buccal cavity. A total of 430 strains of bacteria were cultured and tested for their response to 20 common antibiotic preparations. We were able to confirm the high effectiveness of penicillin and/or broad spectrum penicillin 92% of the cases (8600 determinations of resistance). Tetracycline was effective in 89% of the cases; trimethoprim sulfamethoxazole, in 83%. The effectiveness of newer, more expensive, antibiotic preparations was not significantly better than that of pencillin. Administration of such antibiotic preparations therefore should be limited to problematic pathogens.
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000302:isolation & purification; D002176:Candida albicans / Q000302:isolation & purification; D004352:Drug Resistance, Microbial; D006801:Humans; D010482:Periapical Abscess / Q000188:drug therapy* / Q000382:microbiology; D010508:Periodontal Abscess / Q000188:drug therapy* / Q000382:microbiology; D010518:Periodontitis / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Zur Problematik der bakteriologischen Diagnostik und gezielten Antibiotikatherapie bei pyogenen Infektionen im Kiefer-Gesichts-Bereich.