Experimental flap delay with formic acid.
Using dorsal, cranially based 10 X 3 cm composite pedicle flaps in rats, the effects of an injection of 2 ml of formic acid in different concentrations was studied. Concentrations of 0.2 per cent gave a very significant increase in flap survival over controls. Preoperative penicillin did not influence the outcome.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D005561:Formates / Q000494:pharmacology*; D006085:Graft Survival / Q000187:drug effects*; D051381:Rats; D016038:Skin Transplantation; D014182:Transplantation, Autologous
D005561:Formates