Influence of the major histocompatibility complex in the pig (SLA) on serum haemolytic complement levels.
Sera from fourty-six non-congenic adult pigs from one inter-related herd were tested for their haemolytic serum complement levels. A comparison of these data with the major histocompatibility complex (SLA) genotypes of these animals resulted in the demonstration of highly significant differences in lytic activity between sera obtained from animals of two distinct SLA haplotypes. These data showed a high correlation between the SLA complex and the level of haemolytic activity.
D000818:Animals; D003165:Complement System Proteins / Q000235:genetics*; D003433:Crosses, Genetic; D005260:Female; D005796:Genes; D005838:Genotype; D006462:Hemolytic Plaque Technique; D006649:Histocompatibility Antigens / Q000235:genetics*; D006650:Histocompatibility Testing; D008297:Male; D010375:Pedigree; D013552:Swine / Q000097:blood / Q000235:genetics* / Q000276:immunology
D006649:Histocompatibility Antigens; D003165:Complement System Proteins