Problems in clinical organ preservation.
Effective preservation of donor organs is essential for successful renal cadaver transplantation. Three problems of direct clinical relevance are discussed: (i) agonal damage to the donor kidney; (ii) extracorporeal preservation; (iii) effects of preservation on antigenicity. Current techniques for preserving donor kidneys by continuous perfusion and by ice storage are described.
D000818:Animals; D000941:Antigens; D001926:Brain Death; D002102:Cadaver; D002951:Citrates; D004285:Dogs; D006801:Humans; D006982:Hypertonic Solutions; D007053:Ice; D007511:Ischemia; D007668:Kidney / Q000098:blood supply / Q000276:immunology; D016030:Kidney Transplantation; D009926:Organ Preservation; D010477:Perfusion; D014021:Tissue Preservation; D014184:Transplantation, Homologous
D000941:Antigens; D002951:Citrates; D006982:Hypertonic Solutions; D007053:Ice