Clinical trial of Ferastral in iron-deficient, non-pregnant patients in Ibadan, Nigeria.
Fifteen patients with proven iron-deficiency anaemia treated with intramuscular injections of Ferastral, iron-poly (sorbitol-gluconic acid) complex, have been studied. Fourteen showed a satisfactory rise in haematocrit. No local or systemic complications were observed. One patient with iron-deficiency anaemia due to a bleeding malignant lesion did not achieve a satisfactory haematocrit level although the bone marrow showed iron repletion following the injection. It is concluded that Ferastral is an effective drug in the treatment of iron-deficiency anaemia.
D000747:Anemia, Hypochromic / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D005942:Gluconates / Q000627:therapeutic use; D006400:Hematocrit; D006454:Hemoglobins / Q000096:biosynthesis; D006801:Humans; D007273:Injections, Intramuscular; D007501:Iron / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D009549:Nigeria; D013012:Sorbitol / Q000627:therapeutic use
D004338:Drug Combinations; D005942:Gluconates; D006454:Hemoglobins; D013012:Sorbitol; D007501:Iron