title: In vivo metabolite- antimetabolite relationships in antitumor therapy.
mesh_terms: D000630:Aminopterin / Q000037:antagonists & inhibitors / Q000627:therapeutic use; D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000378:metabolism / Q000627:therapeutic use*; D001711:Biotransformation; D005492:Folic Acid / Q000378:metabolism / Q000494:pharmacology; D002955:Leucovorin / Q000494:pharmacology; D051379:Mice; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism*
chemical_list: D000964:Antimetabolites, Antineoplastic; D005492:Folic Acid; D000630:Aminopterin; D002955:Leucovorin