A comparative controlled trial of pimozide and fluphenazine decanoate in the continuation therapy of schizophrenia.
Evidence from a controlled, comparative trial indicates that oral pimozide is clinically at least as effective as depot injections of fluphenazine decanoate in the continuation therapy of a group of schizophrenic patients discharged from hospital. The administration of pimozide was associated with fewer unwanted effects. The implications of the findings are discussed.
D000328:Adult; D002986:Clinical Trials as Topic; D003863:Depression / Q000188:drug therapy; D005260:Female; D005476:Fluphenazine / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010868:Pimozide / Q000009:adverse effects / Q000627:therapeutic use*; D012008:Recurrence; D012559:Schizophrenia / Q000188:drug therapy*
D010868:Pimozide; D005476:Fluphenazine