Demonstration of Fc receptors on the surface of B lymphocytes.
Human blood lymphocytes were tested by an immunofluorescence technique for surface immunoglobulin and by a rosette test with IgG-sensitised red cells for Fc receptors. From combined tests and experiments involving fractionation of lymphocyte populations it is concluded that Fc receptors are demonstrable on most B lymphocytes by the rosette test, but only if the red cells are optimally sensitised. These observations are advanced as an explanation of the discrepant results of surface marker tests on B cells.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D001666:Binding Sites, Antibody; D002448:Cell Adhesion; D002645:Chickens; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D007141:Immunoglobulin Fc Fragments; D007158:Immunologic Techniques; D011947:Receptors, Antigen, B-Cell; D012397:Rosette Formation
D007141:Immunoglobulin Fc Fragments; D011947:Receptors, Antigen, B-Cell