title: On the metabolic characteristics of Shigella flexneri X Escherichia coli, devoid of ability for intracellular multiplication in epithelial cells. III. Oxygen uptake and dehydrogenase activity.
abstract: The oxygen uptake and dehydrogenase activity of avirulent xyl+ and xyl- str hybrids (KCP-), obtained from virulent strains Sh. flexneri (Sh. flexneri 222 5 a and Sh. flexneri M42-432a) and donor strain E. coli AB 313, devoid of ability for intracellular multiplication in epithelial cells are studied. Some tricarboxylic acid intermediates, hexoses and pentoses were used as substrates. A definite tendency has been established, indicating a decreased rate of oxygen consumption and dehydrogenase activity of the hybrids, compared to the respiratory activity of the virulent recipient strains tsh. flexneri in all substrates used.
mesh_terms: D002460:Cell Line; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D006824:Hybridization, Genetic; D010088:Oxidoreductases / Q000378:metabolism; D010101:Oxygen Consumption; D012763:Shigella flexneri / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity; D014774:Virulence
chemical_list: D010088:Oxidoreductases