[Study of antibiotic sensitivity in 34 strains of large colony mycoplasma (author's transl)].
The application of Steer's technic to large colony mycoplasma for the study of antibiotic sensitivities, permitted us to compare the activity of various molecules inhibiting protein synthesis. Among large colony mycoplasmas, only mycoplasma pneumoniae is sensitive to erythromycin but we have already isolated a strain resistant at 400 microgram/ml. This should be remembered during treatment of mycoplasma pneumoniae infections. This species always remains sensitive to tetracycline. Among the latter, doxycyclin and minocyclin are preferred, firstly for their greater efficacy in vitro and secondly their better pharmacodynamic criteria. Gentamicin, tobramycin and chloramphenicol are also active in vitro. No trial in vivo has been carried out.
D000900:Anti-Bacterial Agents; D002701:Chloramphenicol / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004917:Erythromycin / Q000494:pharmacology; D005839:Gentamicins / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009174:Mycoplasma / Q000187:drug effects*; D013754:Tetracyclines / Q000494:pharmacology; D014031:Tobramycin / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D013754:Tetracyclines; D004917:Erythromycin; D002701:Chloramphenicol; D014031:Tobramycin
Etude de la sensibilité aux antibiotiques de 34 souches de mycoplasmes a grandes colonies.