Pathophysiology of platelet-vessel interactions.
Thrombosis results from the interaction of a number of processes which are summarized in table I and figure 1. The predominant role of platelets in the genesis of rapid-flow, arterial thrombosis provides a rationale for the clinical trial of inhibitors of platelet functions in the management of several thrombotic disorders.
D001777:Blood Coagulation; D001783:Blood Flow Velocity; D001792:Blood Platelets / Q000503:physiopathology*; D004727:Endothelium / Q000503:physiopathology; D006801:Humans; D010974:Platelet Aggregation; D013927:Thrombosis / Q000209:etiology / Q000473:pathology*