title: Oral hypoglycemic agents.
abstract: Oral agents should not be used in the treatment of patients with asymptomatic maturity-onset diabetes. The indication for sulfonylureas is symptomatic maturity-onset diabetes or excessive hyperglycemia--fasting blood sugar over 300 mg per 100 ml--in the elderly patient who cannot or will not take insulin. The use of biguanides cannot be recommended.
mesh_terms: D001645:Biguanides / Q000008:administration & dosage* / Q000009:adverse effects; D002986:Clinical Trials as Topic; D003920:Diabetes Mellitus / Q000188:drug therapy*; D004341:Drug Evaluation; D006801:Humans; D013453:Sulfonylurea Compounds / Q000008:administration & dosage* / Q000009:adverse effects; D013607:Tablets
chemical_list: D001645:Biguanides; D013453:Sulfonylurea Compounds; D013607:Tablets