Inactivation of electrophilic metabolites by glutathione S-transferases and limitation of the system due to subcellular localization.
D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism* / Q000494:pharmacology; D001711:Biotransformation; D003600:Cytosol / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism*; D008297:Male; D051379:Mice; D008862:Microsomes, Liver / Q000378:metabolism; D009153:Mutagens; D012486:Salmonella typhimurium / Q000187:drug effects
D001580:Benzopyrenes; D009153:Mutagens; D005982:Glutathione Transferase; D005978:Glutathione