title: Fetal and maternal risk factors in herpes gestationis.
abstract: Forty-one cases of immunologically proved herpes gestationis (HG) are reviewed and there appears to be an increased risk of fetal morbidity and mortality. The onset of HG is most frequent in the second and third trimesters of pregnancy although postpartum onset or exacerbation is common. The presence of high-titer, antibasement membrane zone antibody seems to correlate with a severe clinical disease. Systemic treatment with corticosteroids is frequently necessary in order to control maternal signs and symtpoms of HG.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000906:Antibodies; D001485:Basement Membrane / Q000276:immunology; D005260:Female; D005313:Fetal Death / Q000209:etiology; D005315:Fetal Diseases / Q000209:etiology; D006801:Humans; D010298:Parity; D006559:Pemphigoid Gestationis / Q000150:complications / Q000188:drug therapy / Q000276:immunology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000150:complications / Q000188:drug therapy / Q000276:immunology; D011645:Puerperal Infection / Q000209:etiology; D012306:Risk; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy
chemical_list: D000305:Adrenal Cortex Hormones; D000906:Antibodies