title: [Treatment of herpes simplex keratitis with Vidarabin ointment (author's transl)].
abstract: In 20 cases of herpes simplex keratitis the efficacy of Vidarabin ointment has been tested, in 19 cases after corneal abrasion. The eyes were treated once a day and padded until the epithelial defects had closed. Thereafter the ointment was applied 4 times per day for about one week more. On the average epithelial closure had been achieved after 2.4 days, complete normalization of the epithelium after a total of 3.6 days. This therapy results in a considerable shortening of the healing process as compared to the topical use of anti-viral medication alone. From this aspect Vidarabin ointment has proved to be a valuable adjuvant.
mesh_terms: D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004361:Drug Tolerance; D006801:Humans; D007635:Keratitis, Dendritic / Q000188:drug therapy*; D009824:Ointments; D013997:Time Factors; D014740:Vidarabine / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D009824:Ointments; D014740:Vidarabine
vernacular_title: Dei Behandlung der Herpes-simplex-Keratitis mit Vidarabin-Augensalbe.