Partial amino acid sequence of penicillinase coded by Escherichia coli plasmid R6K.
Direct studies of the amino acid sequence of an Escherichia coli plasmid-coded penicillinase (penicillin amido-beta-lactamhydrolase, EC 3.5.2.6) are in complete agreement with results derived from the translation of the DNA sequence of a related plasmid, apart from a single amino acid substitution. This penicillinase from a Gram-negative bacterium shows 30-35% identity with functionally similar enzymes from Gram-positive bacteria. This paper should be read in conjunction with the report of the DNA sequence of the gene.
D000595:Amino Acid Sequence; D004926:Escherichia coli / Q000235:genetics*; D010405:Penicillinase / Q000096:biosynthesis / Q000235:genetics*; D010957:Plasmids; D001618:beta-Lactamases / Q000235:genetics*
D010405:Penicillinase; D001618:beta-Lactamases