title: Terbutaline's effects on the allergy skin test.
abstract: Beta adrenergic agents are known to inhibit mediator release from skin and lung mast cells in vitro and isoproterenol and epinephrine are known to impair the immediate allergic skin test reaction. We undertook to investigate the effects of aqueous and oral terbutaline on the allergy skin tests. We particularly wished to analyze the impact of terbutaline on the late allergic reaction, but we found that terbutaline mixed with ragweed antigen does not affect either the immediate or late skin test reaction. Furthermore, 5 mg of oral terbutaline does not inhibit the immediate allergic skin test.
mesh_terms: D002986:Clinical Trials as Topic; D003864:Depression, Chemical; D004311:Double-Blind Method; D006801:Humans; D006969:Hypersensitivity, Immediate; D010919:Placebos; D012882:Skin Tests; D013726:Terbutaline / Q000494:pharmacology*
chemical_list: D010919:Placebos; D013726:Terbutaline