The susceptibility of Candida albicans to amphotericin B, nystatin, and 5-fluorocytosine.
Sensitivity tests were performed on 332 consecutive isolates of Candida albicans. All isolates were inhibited by 0.5 microgram/ml of amphotericin B, and 6.4 microgram/ml of nystatin; and 92.5% of strains were inhibited by 25 microgram/ml of 5-fluorocytosine. Therefore, all three drugs may be employed clinically in the treatment of candidiasis with a reasonable chance of success.
D000666:Amphotericin B / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D003596:Cytosine / Q000031:analogs & derivatives*; D004352:Drug Resistance, Microbial; D005437:Flucytosine / Q000494:pharmacology*; D009761:Nystatin / Q000494:pharmacology*
D009761:Nystatin; D000666:Amphotericin B; D003596:Cytosine; D005437:Flucytosine