A comparative evaluation of fenoterol and terbutaline in the treatment of asthma.
In a double-blind trial of six weeks' duration 30 chronic asthmatic outpatients were treated with 5 mg tablets of either fenoterol or terbutaline two to four times daily. In pulmonary function tests on days 1, 21 and 42 there were no statistically significant differences between the two drugs in terms of mean increases in FEV1 or in duration of effect. No decline in efficacy musculoskeletal side effects declined as the study progressed.
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000188:drug therapy*; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004341:Drug Evaluation; D004983:Ethanolamines / Q000627:therapeutic use*; D005260:Female; D005280:Fenoterol / Q000009:adverse effects / Q000627:therapeutic use*; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008450:Maximal Midexpiratory Flow Rate; D008875:Middle Aged; D011674:Pulse / Q000187:drug effects; D013726:Terbutaline / Q000009:adverse effects / Q000627:therapeutic use*; D013997:Time Factors
D004983:Ethanolamines; D005280:Fenoterol; D013726:Terbutaline