Superiority of human complement for assaying bacterial lipopolysaccharides by their anticomplementary activity.
In assaying bacterial lipopolysaccharides (LPS) for anticomplementary activity, human complement (C) allowed detection of approximately 200 times smaller amounts of LPS than guinea-pigs C. Pig C was slightly inferior to human.
D000818:Animals; D003167:Complement Activation / Q000187:drug effects*; D003169:Complement Inactivator Proteins / Q000032:analysis*; D004926:Escherichia coli; D006168:Guinea Pigs; D006801:Humans; D008070:Lipopolysaccharides / Q000494:pharmacology*; D011135:Polysaccharides, Bacterial / Q000494:pharmacology; D013045:Species Specificity; D013552:Swine
D003169:Complement Inactivator Proteins; D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial