title: [Study of the mechanism of reduction of the virulence in the Shigella flexneri strains resistant to streptomycin].
abstract: Streptomycin-resistant mutations in donor strains of E. coli K12 Hfr AB 313 and AT-13 are not associated with the action of the strA-gene limiting the suppression. Shigella mutations str-r obtained by the method described in this paper also failed to limit the suppression. Changes in the virulence observed in transmission strA region from the str-r strains of E. coli and shigellae used in this work were not connected with mutations limiting the suppression (with competent mutations).
mesh_terms: D000483:Alleles; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000235:genetics; D006824:Hybridization, Genetic; D009154:Mutation; D012763:Shigella flexneri / Q000187:drug effects / Q000235:genetics / Q000472:pathogenicity*; D013307:Streptomycin / Q000494:pharmacology*; D014161:Transduction, Genetic; D014774:Virulence
chemical_list: D013307:Streptomycin
vernacular_title: Izuchenie mekhanizma snizheniia virulentnosti u rezistentnykh k streptomitsinu shtammov Shigell flexnera.