Positive cross-match for B-lymphocyte antigens (IA like) and kidney allograft behaviour.
We describe six cases of kidney graft performed against a positive anti-B lymphocyte cross-match. These antibodies were found after retrospective and systematic screening of the effect of the recipient sera upon donor frozen B lymphocytes. As opposed to the consequences of anti-HLA "SD" preimmunisation, none of the transplantation rapported here failed by acute rejection. The benefic role of anti-B lymphocyte antibodies "Ia like" present at the time of grafting is then suggested.
D000906:Antibodies / Q000032:analysis; D001402:B-Lymphocytes / Q000276:immunology*; D003176:Complement C3 / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D006084:Graft Rejection; D006650:Histocompatibility Testing; D006801:Humans; D007141:Immunoglobulin Fc Fragments; D066298:In Vitro Techniques; D016030:Kidney Transplantation; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology; D014181:Transplantation Immunology; D014184:Transplantation, Homologous
D000906:Antibodies; D003176:Complement C3; D007141:Immunoglobulin Fc Fragments