Evaluation of treatment of lepromatous leprosy patients in the Netherlands.
The results of treatment of the group of leprosy patients at the lepromatous side of the leprosy spectrum registered at the Department of Dermatology of the University of Amsterdam in the years 1950-1976 were studied. The average duration of treatment to obtain bacteriologically negative skin biopsies in patients who were untreated at the time of registration, was 5 years. A substantial number of patients suffered a relapse; the main reasons for these relapses were discontinuation of treatment and DDS treatment in low dosage.
D002986:Clinical Trials as Topic; D002991:Clofazimine / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D004341:Drug Evaluation; D006801:Humans; D007917:Leprostatic Agents / Q000627:therapeutic use*; D007918:Leprosy / Q000188:drug therapy*; D009426:Netherlands; D010670:Phenylthiourea / Q000031:analogs & derivatives / Q000627:therapeutic use; D012008:Recurrence; D012293:Rifampin / Q000627:therapeutic use; D013997:Time Factors
D007917:Leprostatic Agents; D010670:Phenylthiourea; D003622:Dapsone; D002991:Clofazimine; D012293:Rifampin