[The importance of herpes simplex virus type 2 (HSV-2) infection pregnancy and the period following birth (author's transl)].
The Type 2 herpes simplex virus is mainly localized in the genital region and is transmitted by sexual intercourse. A distinction must be made between primary and recurrent infection. During pregnancy, infection of the generative tract with HSV-2 can be expected in 0.1% of cases, depending on the patient's social status. It was possible to culture HSV-2 from the cervical secretion in 0.65% of an investigated group of pregnant women. Fifty percent of all infections in pregnancy are asymptomatic. Miscarriages are common before the 20th week of pregnancy (33%), while later there is a slight increase in premature confinement. Where HSV-2 infection exists at the time of birth, cesarean section is the method of choice for delivery. If rupture of the amnion has occurred over 4 hours previously surgical delivery to prevent infection is no longer justified. A start has been made on therapy for herpes genitalis and neonatal herpes, although sufficient experience for therapeutic recommendations has not yet been gathered.
D000022:Abortion, Spontaneous / Q000209:etiology; D000914:Antibodies, Viral / Q000302:isolation & purification; D005260:Female; D006561:Herpes Simplex / Q000175:diagnosis / Q000517:prevention & control / Q000635:transmission*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis / Q000517:prevention & control / Q000635:transmission*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000517:prevention & control / Q000635:transmission*
D000914:Antibodies, Viral
Die Bedeutung der Herpes-simplex-Virus-Typ 2-(HSV-2)-Infektion für Schwangerschaft und Neugeborenenperiode.