[Dynamics of the amount of fluid in the chest cavity and lower extremities in cardiac insufficiency under the influence of strophanthin and lasix].
The effect of lasix (in 51 patients) and strophanthin (in 16 patients) on the dynamics of changes in the amount of fluid in the chest and leg in cardiac insufficiency was studied by impedance plethysmography. It was established that in isolated insufficiency of only the left parts of the heart, parenteral administration of 20 mg of lasix led almost in all cases to a decrease in the total amount of fluid in the chest and its organs by 14% on the average; the decrease in the volume of fluid in pulmonary edema, cardiac asthma, and insufficiency of the left parts of the heart without acute manifestations is practically the same and amounts to 17, 14, and 12% on the average, respectively. In isolated hypervolemia of the pulmonary circulation, lasix causes a decrease in the amount of fluid in the leg also, by 7% on the average, in three fourths of cases. In total cardiac insufficiency, lasix reduces the volume of fluid in the chest and leg to a similar degree (by 13 and 16% on the average) practically in all cases.
D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004487:Edema / Q000188:drug therapy* / Q000209:etiology; D005665:Furosemide / Q000627:therapeutic use*; D006333:Heart Failure / Q000150:complications*; D006801:Humans; D007866:Leg / Q000098:blood supply*; D011654:Pulmonary Edema / Q000188:drug therapy* / Q000209:etiology; D013328:Strophanthins / Q000627:therapeutic use*
D013328:Strophanthins; D005665:Furosemide
Dinamika kolichestva zhidkosti v grudnoĭ kletke i nizhneĭ konechnosti pri serdechnoĭ nedostatochnosti pod vliianiem strofantina i laziksa.