[Biological compatibility of polyurethan (PUR) (author's transl)].
After implantation of a disc (thickness: 0.25 mm, diam: 1.5 mm) of PUR in the anterior chamber of rabbits through a lancet incision, the reactions of iris, aqueous, and cornea were observed for six months at regular intervals using slit-lamp photography. 'Steeping' materials were as compatible as nonsteeping materials. At the place where the disc touched the iris one could see during a half-year period hyperemia iridis and foreign-substance granuloma of the iris. The cause of these reactions is a toxin in the PUR. Mechanical irritants as a cause could be excluded through the method utilized in the experiment.
D000818:Animals; D000867:Anterior Chamber; D001082:Aqueous Humor / Q000187:drug effects; D001672:Biocompatible Materials; D003315:Cornea / Q000187:drug effects; D005549:Foreign-Body Reaction; D007498:Iris / Q000187:drug effects*; D011140:Polyurethanes / Q000633:toxicity*; D011817:Rabbits
D001672:Biocompatible Materials; D011140:Polyurethanes
Zur biologischen Verträglichkeit von vernetztem Polyurethan (PUR).