title: Dry-heat destruction of lipopolysaccharide: mathematical approach to process evaluation.
abstract: A mathematical model was developed to estimate the number of logarithmic cycles (LDec) of lipopolysaccharide concentration destroyed by a dry-heat sterilization process. The LDec values calculated from the mathematical model agreed well with those obtained from the destruction of lipopolysaccharide by a dry-heat treatment. A discussion of how the mathematical model may be used to evaluate a dry-heat sterilization cycle is presented. This mathematical model and the dry-heat destruction curves indicated existence of a maximum LDec value at each temperature. The implications of this finding are discussed.
mesh_terms: D004926:Escherichia coli; D005069:Evaluation Studies as Topic; D006358:Hot Temperature; D008070:Lipopolysaccharides / Q000378:metabolism*; D008962:Models, Theoretical; D013242:Sterilization
chemical_list: D008070:Lipopolysaccharides