title: Local en bloc resection for limb preservation.
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000601:surgery*; D002986:Clinical Trials as Topic; D004317:Doxorubicin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005121:Extremities / Q000601:surgery*; D005260:Female; D006801:Humans; D007595:Joint Prosthesis; D002955:Leucovorin / Q000627:therapeutic use; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D009362:Neoplasm Metastasis; D012516:Osteosarcoma / Q000601:surgery*; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D002955:Leucovorin; D008727:Methotrexate