[Double blind study of the action of two topic drugs on the thrombosis of the carotid artery of rats after microsuture (author's transl)].
The action of 2 topic agents on the thrombosis of the carotid artery after microsuture was studied in rats. These drugs were magnesium sulfate whose antithrombotic effect has been demonstrated in vitro, and Ringer lactate considered inactive on coagulation. Twenty-two randomized rats underwent an end-to-end microsuture of the primitive carotid artery, the solutions being used to wash the lumen of the vessel and to irrigate the operative field. Arterial patency was controlled after one hour and after 10 days. No statistically significant difference was found between the two series.
D000818:Animals; D002339:Carotid Arteries / Q000601:surgery*; D002341:Carotid Artery Thrombosis / Q000209:etiology / Q000517:prevention & control*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D007773:Lactates / Q000627:therapeutic use*; D008278:Magnesium Sulfate / Q000627:therapeutic use*; D008297:Male; D008866:Microsurgery; D011183:Postoperative Complications / Q000517:prevention & control*; D051381:Rats; D013536:Suture Techniques
D007773:Lactates; D008278:Magnesium Sulfate
Etude en double aveugle de l'action de deux agents locaux sur la thrombose de la carotide primitive du rat après microsuture.