Anti-tumor effects of interferon and its possible use as an anti-neoplastic agent in man.
Interferon exerts anti-tumour effects in vitro and in vivo in animal experiments. It can also exert an anti-tumour effect on human neoplastic cells in vitro. This article summarizes the results obtained so far in the anti-tumour trials in man in Stockholm. The need for scaled-up production of human interferon is emphasized.
D000328:Adult; D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D002648:Child; D004341:Drug Evaluation; D005347:Fibroblasts / Q000276:immunology; D006801:Humans; D007372:Interferons / Q000008:administration & dosage / Q000302:isolation & purification / Q000627:therapeutic use*; D007962:Leukocytes / Q000276:immunology; D009369:Neoplasms / Q000188:drug therapy*; D009374:Neoplasms, Experimental / Q000188:drug therapy*; D009928:Organ Specificity; D012516:Osteosarcoma / Q000188:drug therapy
D007372:Interferons