title: [Male sex hormones and their derivatives. Pathophysiology and therapy].
abstract: After a short review of the chemistry, biosynthesis and physiology (regulation of production and secretion, effects) of the male sex hormones, the possible disturbances of the male sex hormones, the possible disturbances of the male sex function are pathophysiologically listed and some instructive diseases, as castration, testicular feminization, Kallmann syndrome, prolactinoma and flour-bag-drawfs, are discussed. Regarding the main topic, influence of general diseases on sex hormones, the implications of the cirrhosis of the liver and the dialysis in kidney disease are listed as examples. Indications and particularly the contraindications and dangers of testosterone and anabolic steroid therapy are discussed.
mesh_terms: D000302:Adrenal Cortex / Q000378:metabolism; D013734:Androgen-Insensitivity Syndrome; D002369:Castration; D004967:Estrogens / Q000378:metabolism; D007987:Gonadotropin-Releasing Hormone / Q000172:deficiency; D006801:Humans; D007006:Hypogonadism / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000378:metabolism; D007985:Leydig Cells / Q000378:metabolism; D008103:Liver Cirrhosis / Q000378:metabolism; D008297:Male; D011218:Prader-Willi Syndrome / Q000209:etiology; D013739:Testosterone / Q000502:physiology*; D013959:Thyroid Diseases / Q000378:metabolism
chemical_list: D004967:Estrogens; D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone
vernacular_title: Die männlichen Sexualhormone und ihre Derivate.