title: Quantitative determination of prostatic epithelial and stromal hyperplasia by a new technique. Biomorphometrics.
abstract: Recent studies of neonatal and pathologic growth of the prostate have postulated the possible importance of stromal-epithelial interaction in the control of prostatic growth. To allow further analysis of the possible importance of this interaction, a new technique has been developed that permits quantification of the total number of stromal and epithelial cells in the prostate gland. This technique has been termed biomorphometrics and is a combination of standard morphometric and biochemical methodology. This method has been applied to analyze the hormonal response of the stromal and epithelial cells of the rat ventral prostate.
mesh_terms: D000818:Animals; D002452:Cell Count / Q000379:methods*; D002467:Cell Nucleus; D004247:DNA / Q000032:analysis; D004848:Epithelium / Q000473:pathology; D012739:Gonadal Steroid Hormones / Q000494:pharmacology; D006652:Histological Techniques; D006965:Hyperplasia; D008297:Male; D008433:Mathematics; D008853:Microscopy / Q000379:methods; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*; D051381:Rats
chemical_list: D012739:Gonadal Steroid Hormones; D004247:DNA