title: Catecholamines in shock.
abstract: The role of endogenous catecholamines in various clinical shock and stress states is reviewed; the effects, especially on the peripheral circulation, of catecholamine secretion are the same independent of the cause. Risks of using sympathomimetic agents in the treatment of shock are evaluated. A prolonged noradrenaline activity is to be expected in surgical stress states, e.g. multiple injuries, fat embolism syndrome, burns and infections; therapeutic approaches to minimize the sympathoadrenal activity are outlined.
mesh_terms: D002395:Catecholamines / Q000037:antagonists & inhibitors / Q000097:blood / Q000378:metabolism*; D004620:Embolism, Fat / Q000503:physiopathology; D006801:Humans; D008833:Microcirculation; D009638:Norepinephrine / Q000097:blood / Q000378:metabolism; D012769:Shock / Q000188:drug therapy / Q000503:physiopathology*; D012770:Shock, Cardiogenic / Q000503:physiopathology; D012772:Shock, Septic / Q000503:physiopathology; D013312:Stress, Physiological; D013514:Surgical Procedures, Operative; D014662:Vasoconstrictor Agents / Q000627:therapeutic use; D014947:Wounds and Injuries / Q000503:physiopathology
chemical_list: D002395:Catecholamines; D014662:Vasoconstrictor Agents; D009638:Norepinephrine