Ferastral treatment of three healthy phlebotomized males.
Iron deficiency anaemia was produced by repeated phlebotomies in three healthy males. The storage iron was estimated as 666, 522 and 750 mg. After treatment with 1 000 mg of Ferastral the blood haemoglobin concentration rose at an average daily rate of 0.1 g/100 ml/day. Ninety per cent of the injected iron could be accounted for, and the utilization was estimated to about 70-80%. Side effects comprised pain and discolouration at the injection site.
D000328:Adult; D000747:Anemia, Hypochromic / Q000188:drug therapy*; D001815:Bloodletting; D002986:Clinical Trials as Topic; D004338:Drug Combinations; D005942:Gluconates / Q000627:therapeutic use; D006801:Humans; D007501:Iron / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D013012:Sorbitol / Q000627:therapeutic use
D004338:Drug Combinations; D005942:Gluconates; D013012:Sorbitol; D007501:Iron