[Evolution towards generalization and cancer of a muco-cutaneous leishmaniasis treated with corticoids. (Report of a Chadian case) (author's transl)].
The authors present a case of muco-cutaneous leishmaniasis in the Republic of Chad. In that case, a long duration treatment with corticoids entailed the generalization of the disease in the form of a secondary kala-azar and the appearance of a histiocytosarcoma on the scar left by the oriental sore. Comments on the pathogenesis of leishmaniasis are then exposed.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007153:Immunologic Deficiency Syndromes / Q000276:immunology; D007897:Leishmaniasis, Mucocutaneous / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D007898:Leishmaniasis, Visceral / Q000209:etiology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000209:etiology* / Q000473:pathology; D008297:Male; D008536:Meglumine / Q000627:therapeutic use; D009303:Nasopharyngeal Neoplasms / Q000209:etiology* / Q000473:pathology; D009666:Nose / Q000473:pathology; D010419:Pentamidine / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D010419:Pentamidine; D008536:Meglumine
Genéralisation et cancérisation, sous corticothérapie, d'une leishmaniose cutanéo-muqueuse (à propos d'un cas observé au Tchad).