Swiss and inbred mice in the infant mouse test for the assay of Escherichia coli thermostable enterotoxin.
Swiss and inbred mice (C3H, ASn, B10A, and C57) were used to assay different thermostable enterotoxins prepared from Escherichia coli strains 3 (human), E57 (swine), B41 (cattle), and S13 (sheep). All strains of mice detected enterotoxins, but some reacted better to a given thermostable enterotoxin preparation than other inbred strains. Since the results obtained with Swiss mice were more consistent than with inbred mice, the former are apparently more suitable in the infant mouse test.
D000704:Analysis of Variance; D000818:Animals; D001681:Biological Assay; D004768:Enterotoxins / Q000032:analysis* / Q000494:pharmacology; D004926:Escherichia coli; D006358:Hot Temperature; D007422:Intestines / Q000187:drug effects*; D051379:Mice; D008815:Mice, Inbred Strains; D009929:Organ Size / Q000187:drug effects; D013045:Species Specificity
D004768:Enterotoxins