Biochemical markers in Hodgkin's disease and non-Hodgkin's lymphoma.
Vertical studies indicate that, in general, acute phase reactant proteins (APRP) reflect disease activity in both Hodgkin's disease and non-Hodgkin's lymphoma. Longitudinal studies of the selected APRP profile demonstrate the following: 1. The stable profile is characteristic of remission. 2. Considerable elevation of APRPs coincides with relapsed disease. 3. An unstable profile is a feature of relapsing disease and may give early warning of relapse. 4. Patients responding inadequately to treatment frequently have unstable APRP profiles.
D000328:Adult; D002097:C-Reactive Protein / Q000032:analysis; D002918:Chymotrypsin / Q000037:antagonists & inhibitors; D005260:Female; D006023:Glycoproteins / Q000097:blood; D006689:Hodgkin Disease / Q000097:blood*; D006801:Humans; D008223:Lymphoma / Q000097:blood*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000097:blood; D008228:Lymphoma, Non-Hodgkin / Q000097:blood; D008297:Male; D008875:Middle Aged; D009961:Orosomucoid / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis
D006023:Glycoproteins; D009961:Orosomucoid; D000515:alpha 1-Antitrypsin; D002097:C-Reactive Protein; D002918:Chymotrypsin