Dexamethasone in acute stroke.
Over 13 months 118 patients admitted to hospital with acute stroke were allocated at random to treatment with either dexamethasone or placebo. At one year there was no significant difference in the numbers of survivors or in the quality of life between the two groups. The results suggest that there is no indication for the routine administration of dexamethasone to a heterogeneous group of patients with stroke.
D000208:Acute Disease; D002561:Cerebrovascular Disorders / Q000097:blood / Q000134:cerebrospinal fluid / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007273:Injections, Intramuscular; D008297:Male; D011188:Potassium / Q000097:blood; D011897:Random Allocation; D013997:Time Factors
D003907:Dexamethasone; D011188:Potassium; D006854:Hydrocortisone