title: Tympanoplasty with preformed autologous ossicles.
abstract: A method of creating a preformed new bone graft from the patient's temporal region using a titanium mould is described. The preliminary work which was performed on animals demonstrated the ability to generate healthy bone in this way. Subsequent application of this technique to the problems of ossicular reconstruction in human ears has proved encouraging in selected cases.
mesh_terms: D000818:Animals; D001705:Bioprosthesis; D016025:Bone Transplantation; D004285:Dogs; D004429:Ear Ossicles; D006801:Humans; D011817:Rabbits; D013701:Temporal Bone / Q000601:surgery; D014025:Titanium; D014182:Transplantation, Autologous; D014433:Tympanoplasty / Q000379:methods*
chemical_list: D014025:Titanium