[Cardio-circulatory effects of aminophylline (Euphyllin) (author's transl)].
In 24 patients with congenital or acquired heart disease, functional class II--IV New York Heart Association Classification, effects of aminophylline on hemodynamics have been investigated intraoperatively, during extracorporeal circulation and postoperatively. Aminophylline caused a decrease in arterial pressure, left ventricular pressure, right and left atrial pressure, total systemic resistance and total pulmonary resistance. At the same time there was an increase in heart peak, peak dp/dt, cardiac index and stroke index. Our results demonstrate beneficial cardiac and extracardiac effects of aminophylline in man.
D000328:Adult; D000403:Airway Resistance / Q000187:drug effects; D000628:Aminophylline / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D006348:Cardiac Surgical Procedures; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005112:Extracorporeal Circulation; D006321:Heart / Q000187:drug effects*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008875:Middle Aged; D011184:Postoperative Period; D014655:Vascular Resistance / Q000187:drug effects
D000628:Aminophylline
Beeinflussung von Herzkreislaufparametern durch Aminophyllin (Euphyllin).