The effect of oxisuran, a selective inhibitor of cellular immunity, on the rejection of bovine corneal xenografts in rabbits.
Oxisuran, a selective inhibitor of cellular immunity, delayed the rejection of bovine corneal xenografts when it was administered intraperitoneally to rabbits. The drug produced no significnat effect on the production of humoral antibody in response to injected sheep erythrocytes.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D002417:Cattle / Q000276:immunology; D016039:Corneal Transplantation; D006084:Graft Rejection / Q000187:drug effects*; D006388:Hemagglutinins / Q000096:biosynthesis; D007111:Immunity, Cellular / Q000187:drug effects*; D011725:Pyridines / Q000627:therapeutic use* / Q000633:toxicity; D011817:Rabbits; D014183:Transplantation, Heterologous
D006388:Hemagglutinins; D011725:Pyridines