title: Median rhomboid glossitis: not a misnomer. Review of the literature and histologic study of twenty-eight cases.
abstract: A series of twenty-eight cases of median rhomboid glossitis were studied histologically. Of these twenty-eight cases, 85 percent showed fungal hyphae in the parakeratin layer. The literature is reviewed, and additional evidence is presented to support the theory the median rhomboid glossitis is not a developmental condition but the clinical expression of a localized chronic fungal infection.
mesh_terms: D000328:Adult; D000368:Aged; D002176:Candida albicans / Q000166:cytology; D002180:Candidiasis, Oral / Q000150:complications*; D003238:Connective Tissue / Q000473:pathology; D003937:Diagnosis, Differential; D004848:Epithelium / Q000473:pathology; D005260:Female; D005928:Glossitis / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D007642:Keratosis / Q000473:pathology; D008297:Male; D008875:Middle Aged