title: A comparative assessment of carbuterol, fenoterol and hexoprenaline in allergic asthma.
abstract: Carbuterol tablets (2,0 mg) were compared with the tablets of fenoterol (2,5 mg) and hexoprenaline (1 mg). The three drugs were shown to be equally effective for a period of 4 hours, but carbuterol and fenoterol exerted a statistically significant bronchodilating action for 7 and 8 hours respectively, while the action of hexoprenaline lasted for 4 hours in the majority of patients. The aerosols of carbuterol (200 mg) and fenoterol (400 mg) appeared to be similar in inhibiting exercise-induced asthma, whereas hexoprenaline (200 mg) did not appear to be as effective.
mesh_terms: D000293:Adolescent; D000328:Adult; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy; D001794:Blood Pressure / Q000187:drug effects; D001980:Bronchi / Q000187:drug effects; D002986:Clinical Trials as Topic; D004983:Ethanolamines / Q000008:administration & dosage / Q000494:pharmacology; D005260:Female; D005280:Fenoterol / Q000008:administration & dosage / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D006594:Hexoprenaline / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010627:Phenethylamines / Q000008:administration & dosage; D012123:Pulmonary Ventilation; D013607:Tablets
chemical_list: D000336:Aerosols; D004983:Ethanolamines; D010627:Phenethylamines; D013607:Tablets; D005280:Fenoterol; D006594:Hexoprenaline