[Natural antibodies (isohemagglutinins, heterophilic, antierythrocytic and antibacterial) in children with congenital immunologic deficiency syndromes].
Examination of 30 patients with immunodeficient diseases showed that the system of natural antibodies was considerably changed depending on the form and the extent of deficiency of the immune system: in agammaglobuinemia the antibodies under study were almost completely absent, and in immunological insufficiency with ataxia-teleangiectasis the production of antibacterial antibodies proved to be sharply decreased. The data obtained can be used both for the diagnosis of immunodeficiencies and for control of the restoration of the immunological competence after a number of therapeutic measures, particularly after the transplantation of the thymus-sternum complex.
D000293:Adolescent; D000373:Agglutinins / Q000302:isolation & purification*; D000818:Animals; D000907:Antibodies, Bacterial / Q000302:isolation & purification*; D001260:Ataxia Telangiectasia / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D004285:Dogs; D004912:Erythrocytes / Q000276:immunology; D004926:Escherichia coli / Q000276:immunology; D006168:Guinea Pigs; D006801:Humans; D007113:Immunity, Innate; D007153:Immunologic Deficiency Syndromes / Q000151:congenital* / Q000276:immunology; D007518:Isoantibodies / Q000302:isolation & purification*; D051379:Mice; D011817:Rabbits; D051381:Rats; D012756:Sheep
D000373:Agglutinins; D000907:Antibodies, Bacterial; D007518:Isoantibodies
Estestvennye antitela (izogemaggliutininy, geterofil'nye, antieritrotsitarnye i antibakterial'nye) u deteĭ s vrozhdennymi immunodefitsitnymi zabolevaniiami.