Suprasellar extension of tumour associated with increased cerebrospinal fluid activity of LH and FSH.
A 65 year old man with pituitary adenoma, partial hypopituitarism and normal serum FSH and LH concentration is described. LH (but not FSH) partially increased following the administration of LH-RH. Subsequent FSH and LH assays of the cerebrospinal fluid, however, showed a high and correctly predicted suprasellar extension of the tumour.
D000236:Adenoma / Q000134:cerebrospinal fluid* / Q000601:surgery; D000368:Aged; D005640:Follicle Stimulating Hormone / Q000097:blood / Q000134:cerebrospinal fluid*; D007987:Gonadotropin-Releasing Hormone; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood / Q000134:cerebrospinal fluid*; D008297:Male; D010911:Pituitary Neoplasms / Q000134:cerebrospinal fluid* / Q000601:surgery; D013739:Testosterone / Q000097:blood; D013963:Thyroid Hormones / Q000097:blood
D013963:Thyroid Hormones; D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone