title: [Role of antibodies in protection from pseudotuberculous infection and intoxication].
abstract: Lethal doses of virulent pseudotuberculosis bacilli and antipseudotuberculosis sera of different specificity were injected to albino mice simultaneously. A high neutralizing activity of antibodies against pseudotuberculosis intoxication was demonstrated. The type-specific antibodies proved to protect the mice from the toxins of the homologous types of the microbe only. Group antibodies of plaque antiserum and serum procured from the pseudoteburculosis convalescent produced a cross antitoxic action. The antiinfectious effect from the antibody administration was weak. Apparently in pseudotuberculosis the antibodies were the principal factor of the toxin neutralization and were of auxiliary significance in the protection from the developing infection. Neutralization of pseudotuberculosis toxins with plague antiserum served as an additional confirmation of cross immunity between plague and pseudotuberculosis.
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial; D000918:Antibody Specificity; D003429:Cross Reactions; D006736:Horses / Q000276:immunology; D006801:Humans; D007116:Immunization, Passive; D010930:Plague / Q000276:immunology; D011817:Rabbits / Q000276:immunology; D015009:Yersinia Infections / Q000517:prevention & control*; D015012:Yersinia pseudotuberculosis Infections / Q000276:immunology / Q000517:prevention & control*
chemical_list: D000907:Antibodies, Bacterial
vernacular_title: Rol' antitel v zashchite ot psevdotuberkuleznoĭ infektsii i intoksikatsii.