Comparison of quinestrol and Tace for relief of postpartum breast discomfort.
A single 2-mg dose of quinestrol was demonstrated safe and effective for controlling postpartum lactation and for alleviating breast discomfort. A double-blind comparison to Tace 72 mg every 12 hours for 2 days, and to placebo, was made in 134 patients. The single oral dose of quinestrol showed efficacy equal to the 2-day regimen of Tace. Both were superior to placebo.
D000293:Adolescent; D000328:Adult; D002741:Chlorotrianisene / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007774:Lactation / Q000187:drug effects*; D009651:Norpregnatrienes / Q000494:pharmacology*; D011247:Pregnancy; D011800:Quinestrol / Q000494:pharmacology*
D009651:Norpregnatrienes; D002741:Chlorotrianisene; D011800:Quinestrol