title: Single-dose antibiotic prophylaxis in appendectomy.
abstract: Prophylactic antibiotics will reduce the number of wound infections after so-called clean-contaminated gastrointestinal operations. The prophylactic regimen must be designed with the pharmacokinetical properties of the used drug, in mind. A safe and simple, easily standardized procedure, applicable in both elective and acute clinical situations is preferable. A single-dose regimen with prophylactic cephaloridine has been tried and evaluated.
mesh_terms: D001062:Appendectomy; D002509:Cephaloridine / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005500:Follow-Up Studies; D006801:Humans; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D002509:Cephaloridine