A micromethod for simultaneous estimation of blood levels of some commonly used antiepileptic drugs.
The analysis of serum samples for the antiepileptic drugs carbamazepine, phenobarbital and phenytoin by a simple extraction technique and chromatographic analysis by high-pressure liquid chromatography is described. The method is a micro one which correlates well with gas-liquid chromatographic procedures. Coefficients of variation are smaller than 3%.
D000927:Anticonvulsants / Q000097:blood*; D002220:Carbamazepine / Q000097:blood; D002849:Chromatography, Gas / Q000379:methods; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003975:Diazepam / Q000097:blood; D006801:Humans; D008832:Microchemistry; D003708:Nordazepam / Q000097:blood; D010634:Phenobarbital / Q000097:blood; D010672:Phenytoin / Q000097:blood
D000927:Anticonvulsants; D002220:Carbamazepine; D010672:Phenytoin; D003708:Nordazepam; D003975:Diazepam; D010634:Phenobarbital