[Common antigens of stable group A streptococcal L forms and muscle fibers of human myocardium].
The immunofluorescence method was used to demonstrate that the antigens of stable streptococcus L-forms and of the cytoplasmic membrane of human myocardium muscle fibers were common. The common antigen was included into the composition of the surface membrane of the muscle cell adjacent to the sarcolemma, and of the transverse tubule membranes of the sarcoplasma reticulum passing in the Z-band region of the muscle fiber sarcomeres. The reactions is completely prevented by the exhaustion of the anti-serum to the antigen of the L-forms with the homogenate of human myocardium tissues or a suspension of the L-form cultures grown both on meat and on casein media. Exhaustion with tissue homogenate of other organs (the liver) or with concentrated nutrient medium practically failed to influence the extent of this reaction. The authors believe that the commonnes of the antigens of stable L-forms of streptococcus, group A, cultures and of the myocardium could serve as one of the causes of prolonged persistence of L-forms in human and animal organism.
D000818:Animals; D015478:Antigens, Heterophile; D005455:Fluorescent Antibody Technique; D006801:Humans; D007740:L Forms / Q000276:immunology*; D009206:Myocardium / Q000276:immunology*; D011817:Rabbits / Q000276:immunology; D013297:Streptococcus pyogenes / Q000276:immunology*
D015478:Antigens, Heterophile
Obshchie antigeny stabil'nykh L-form streptokokka gruppy A i myshechnykh volokon miokarda cheloveka.