[Plasma LH response to LHRH in hypothyroid and thyroxin-treated rats (author's transl)].
Plasma LH response after intravenous injection of synthetic LHRH (50 ng) was studied in male rats (normal, after thyroidectomy, after treatment by dl thyroxin 50 microgram/a day, 10 days). LH response was significantly elevated in hypothyroid animals although it was not influenced by thyroxin injections. Prolonged plasma LH half-life in hypothyroid rats can account in this result.
D000818:Animals; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage*; D007037:Hypothyroidism / Q000097:blood*; D007275:Injections, Intravenous; D007986:Luteinizing Hormone / Q000097:blood* / Q000378:metabolism; D008297:Male; D051381:Rats; D013268:Stimulation, Chemical; D013965:Thyroidectomy; D013974:Thyroxine / Q000008:administration & dosage*
D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone; D013974:Thyroxine
Influence de l'hypothyroïdie et de l'administration de thyroxine sur la réponse LH à LHRH chez le rat.