title: The long term treatment with beta-carotene in erythropoietic protoporphyria: a controlled trial.
abstract: The efficacy of oral beta-carotene for the prevention of photosensitivity symptoms in erythropoietic protoporphyria was studied in a controlled cross-over trial in which it was compared with a placebo. No significant difference was found between the 2 preparations. Patients' symptoms showed statistically significant association with sunlight hour records.
mesh_terms: D000328:Adult; D002338:Carotenoids / Q000097:blood / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004912:Erythrocytes / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D011164:Porphyrias / Q000188:drug therapy*; D011524:Protoporphyrins / Q000097:blood; D013472:Sunlight
chemical_list: D011524:Protoporphyrins; D002338:Carotenoids