Scleroderma: pathogenic factors and current management.
The aetiology of scleroderma remains unknown. Pathogenetic mechanisms may originate from vascular, collagen or immune abnormalities. These are reviewed and the current management although in the main unsatisfactory may alleviate a number of the distressing symptoms.
D001808:Blood Vessels / Q000473:pathology / Q000503:physiopathology; D001809:Blood Viscosity; D003094:Collagen / Q000378:metabolism; D006801:Humans; D008833:Microcirculation; D012595:Scleroderma, Systemic / Q000209:etiology* / Q000276:immunology / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D012867:Skin / Q000378:metabolism / Q000473:pathology
D003094:Collagen