[Clinical studies on the effect of pregnancy and labor on the pharmacokinetics of ampicillin].
After giving 5 g Ampicillin intravenously to a total of 33 women (gravidae during the VIII. month pregnancy, women in labor and health controll persons) the serum levels of the mothers were analysed according to the pharmacokinetic parameter half-life of elimination.--Our results show that only the delivery cause significant differences of the kinetic of ampicillin.--Our results are discussed with the data given by literature.
D000328:Adult; D000667:Ampicillin / Q000378:metabolism* / Q000652:urine; D001711:Biotransformation; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007743:Labor, Obstetric; D011247:Pregnancy; D011263:Pregnancy Trimester, Third
D000667:Ampicillin
Klinische Untersuchungen zum Einfluss von Schwangerschaft und Geburt auf die Pharmakokinetik von Ampizillin.