Interim report: high dosage bromperidol therapy of delirium tremens.
The high dosage of bromperidol as used in this investigation was a safe and effective agent in the treatment of alcohol-induced delirium tremens. All of the 10 patients survived without having complications of the illness or side effects of the therapy. The high doses of bromperidol had a gradual effect against the ten target symptoms of delirium tremens. Particularly effective was the action of bromperidol in controlling hallucinatory phenomena. Against excitement and restlessness, it was rather less effective; no patients were oversedated. Supplementary sedative medication was only rarely needed.
D000328:Adult; D000430:Alcohol Withdrawal Delirium / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D006212:Hallucinations / Q000188:drug therapy; D006220:Haloperidol / Q000008:administration & dosage / Q000031:analogs & derivatives*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011595:Psychomotor Agitation / Q000188:drug therapy; D011604:Psychoses, Alcoholic / Q000188:drug therapy*
D006220:Haloperidol