title: Noradrenergic hyperactivity in opiate withdrawal supported by clonidine reversal of opiate withdrawal.
mesh_terms: D002986:Clinical Trials as Topic; D003000:Clonidine / Q000627:therapeutic use*; D004311:Double-Blind Method; D006556:Heroin Dependence / Q000534:rehabilitation*; D006801:Humans; D008125:Locus Coeruleus / Q000378:metabolism; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D009638:Norepinephrine / Q000378:metabolism*; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D003000:Clonidine; D008691:Methadone; D009638:Norepinephrine