Tissue culture of the epithelium of the normal and cataractous adult lens.
Tissue culture of cataractous lens epithelium shows deterioration of cellular tropism, anisomorphism, anisometry, and formation of large intracytoplasmic vacuoles with deterioration of the lysosomal system, the vacuolated cells showing no tendency to form fibers.
D000328:Adult; D002386:Cataract / Q000378:metabolism / Q000473:pathology*; D002465:Cell Movement; D046508:Culture Techniques; D003593:Cytoplasm; D003594:Cytoplasmic Granules; D004848:Epithelium / Q000378:metabolism / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D007908:Lens, Crystalline / Q000378:metabolism / Q000473:pathology*; D008858:Microscopy, Phase-Contrast; D014617:Vacuoles