title: [Controlled trials of premedication of fiberendoscopy (author's transl)].
abstract: In four controlled studies on 771 consecutive patients we tested the value of premedication before passing a fiberendoscope. Following local anaesthesia of the throat, 10 mgs of diazepam in patients less than 60 years and 5 mgs in those over 60 years quickly injected intravenously caused a sufficient premedication for fiberendoscopy. Premedication with diazepam is better than placebo. We fell that omission of premedication is not justifiable. Flunitrazepam, for premedication, in doses of 1-2 mgs did not prove to be suitable. 20 patients were radiologically controlled for signs of aspiration following premedication and endoskopy. They showed no signs of aspiration.
mesh_terms: D000328:Adult; D000368:Aged; D000772:Anesthesia, Local; D002986:Clinical Trials as Topic; D003975:Diazepam / Q000008:administration & dosage; D004724:Endoscopy; D005336:Fiber Optic Technology; D005445:Flunitrazepam / Q000008:administration & dosage; D006801:Humans; D008875:Middle Aged; D010919:Placebos; D011292:Premedication
chemical_list: D010919:Placebos; D005445:Flunitrazepam; D003975:Diazepam
vernacular_title: Kontrollierte Studien zur Prämedikation von oberen Fiberendoskopien.