[Clinical trial of tramadol by means of the "paired card" system (author's transl)].
1. 1-(m-Methoxyphenyl)-2-(dimethylaminomethyl)-cyclohexan-1-ol (tramadol; Tramal) was administered i.v. to patients suffering from pain of various origins. Its efficacy and side effects were compared with those of metamizole and placebo. 2. Tramadol (100 mg) was as effective as metamizole (2.5 mg) and significantly more effective than placebo. 3. All three compounds showed no significant differences in type and number of side effects.
D000700:Analgesics / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003511:Cyclohexanols / Q000009:adverse effects / Q000627:therapeutic use*; D004177:Dipyrone / Q000627:therapeutic use; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D010146:Pain / Q000188:drug therapy*; D010919:Placebos; D013223:Statistics as Topic
D000700:Analgesics; D003511:Cyclohexanols; D010919:Placebos; D004177:Dipyrone
Klinische Prüfung von Tramadol nach dem Paarlingskarten-System.