Metabolic alpha-hydroxylation of the tobacco-specific carcinogen, N'-nitrosonornicotine.
D000818:Animals; D001711:Biotransformation; D002273:Carcinogens / Q000378:metabolism* / Q000494:pharmacology; D006900:Hydroxylation; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism*; D009153:Mutagens; D009538:Nicotine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D009602:Nitrosamines / Q000378:metabolism* / Q000494:pharmacology; D010947:Plants, Toxic; D051381:Rats; D011916:Rats, Inbred F344; D012486:Salmonella typhimurium / Q000187:drug effects; D014026:Nicotiana
D002273:Carcinogens; D009153:Mutagens; D009602:Nitrosamines; D009538:Nicotine