title: [The effect of various caries preventive agents on the microflora of albino rats].
abstract: An experiment with 80 Wistar rats was performed to study, using cultural methods, the effect of locally and internally applied caries-preventive agents on the microbiological situation in the oral cavity and on the surface of the skin. Especially in case of combined internal and local application, fluoride-containing preparations exerted an inhibitory effect on the oral microflora that had been altered by a cariogenic diet and on the bacterial invasion of the skin. The influence of a locally applied mineral solution on bacterial growth was only insignificant.
mesh_terms: D000818:Animals; D003731:Dental Caries / Q000517:prevention & control*; D004037:Diet, Cariogenic; D004926:Escherichia coli / Q000187:drug effects; D005457:Fluoridation; D005459:Fluorides / Q000627:therapeutic use*; D005460:Fluorides, Topical / Q000627:therapeutic use; D007778:Lactobacillus / Q000187:drug effects; D009055:Mouth / Q000382:microbiology*; D051381:Rats; D012867:Skin / Q000382:microbiology; D013210:Staphylococcus / Q000187:drug effects; D013291:Streptococcus / Q000187:drug effects
chemical_list: D005460:Fluorides, Topical; D005459:Fluorides
vernacular_title: Uber den Einfluss verschiedener Kariespräventiva auf die Mikroflora von Albinoratten.