["Entero-insular axis" and regulation of blood sugar and insulin levels following oral glucose loading].
The mineral water Essentuki 17 administered per so with glucose exerted a modifying effect on the regulation of glycaemia and insulinaemia in intact rats. This effect undergoes a few phases of changing and disappears by the 30th day. Under conditions of this adaptation, the glycaemia regulation is somewhat worsening. After i.v. administration of glucose during this period the regulation of glycaemia and insulinaemia remains unaltered. This suggests that the mineral water exerts its biological effect, mainly, on the entero-insular axis system (Unger and Eisentraut, 1969) and that the modifying effect is due not to a concrete complex of the mineral water electrolytes but rather to the unspecific factor of "perturbation" in the enteral medium.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D005947:Glucose / Q000008:administration & dosage*; D007328:Insulin / Q000097:blood*; D007408:Intestinal Absorption; D007422:Intestines / Q000502:physiology; D007515:Islets of Langerhans / Q000502:physiology; D008900:Mineral Waters; D051381:Rats; D014994:Xylose / Q000378:metabolism
D001786:Blood Glucose; D004040:Dietary Carbohydrates; D007328:Insulin; D008900:Mineral Waters; D014994:Xylose; D005947:Glucose
"Entero-insuliarnaia os'" i regulirovanie glikemii i insulinemii posle peroral'noĭ nagruzki gliukozoĭ.