Antibodies to Candida albicans in human cervicovaginal secretions.
The incidence of IgA and IgG antibodies against Candida albicans was determined in cervicovaginal secretions from 95 non-pregnant women. IgG antibodies were detected in 21.2% of women with vaginal candidosis, in 23.5% of women harbouring yeasts in the vagina without clinical signs of infection, and in 26.6% of women not harbouring yeasts in the vagina. IgA antibodies were found in 6.1% of women with vaginal candidosis, in 5.9% of women harbouring yeasts in the vagina without clinical signs of infection, and in 8.9% of women not harbouring yeasts in the vagina. IgG antibodies against C. albicans were detected in the serum of all 95 women. It is suggested that a proportion of the antibodies found in the secretions was derived from the circulation.
D000293:Adolescent; D000328:Adult; D000908:Antibodies, Fungal / Q000032:analysis*; D002176:Candida albicans / Q000276:immunology*; D002181:Candidiasis, Vulvovaginal / Q000276:immunology; D002582:Cervix Mucus / Q000276:immunology*; D003276:Contraceptives, Oral; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D008598:Menstruation; D008875:Middle Aged; D014621:Vagina / Q000276:immunology* / Q000378:metabolism
D000908:Antibodies, Fungal; D003276:Contraceptives, Oral; D007070:Immunoglobulin A; D007074:Immunoglobulin G