[In vitro biosynthesis of octopamine by the nervous system and the heart of the mollusc gastropode Helix pomatia (author's transl)].
The tyrosine is decarboxylated in vitro by the central nervous tissue and by the intracardiac nervous tissue of Helix pomatia by aromatic amino-acid decarboxylase. The tyramine obtained is then partially transformed into octopamine by tyramine-beta-hydroxylase. The inhibition of monoamine oxidase favours apparition of the 2 amines. The monoamine oxidase seems able to regulate their synthese and to assure their inactivation.
D004299:Dopamine beta-Hydroxylase / Q000378:metabolism; D006372:Helix, Snails / Q000378:metabolism*; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D009206:Myocardium / Q000378:metabolism; D009420:Nervous System / Q000378:metabolism; D009655:Octopamine / Q000096:biosynthesis*; D012621:Seasons; D014439:Tyramine / Q000096:biosynthesis
D008996:Monoamine Oxidase Inhibitors; D009655:Octopamine; D004299:Dopamine beta-Hydroxylase; D014439:Tyramine
Biosynthèse in vitro d'octopamine par le système nerveux et le coeur du mollusque gastéropode Helix pomatia.