title: Lithium treatment of patients with affective illness associated with organic brain symptoms.
abstract: Lithium was used to treat the manic symptoms of affective disorder in three patients with associated organic brain syndromes. In all three cases neuropsychological testing permitted evaluation of the degree of dysfunction during the acute and follow-up periods of treatment. Lithium was effective in controlling the manic symptoms of all three patients, and there was no evidence that it caused further organic deterioration.
mesh_terms: D000368:Aged; D001714:Bipolar Disorder / Q000150:complications / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007361:Intelligence Tests; D008094:Lithium / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000150:complications* / Q000175:diagnosis; D009483:Neuropsychological Tests; D012075:Remission, Spontaneous
chemical_list: D008094:Lithium