Interaction between erythromycin and lincomycin in Streptococcus pyogenes.
Ten strains of Streptococcus pyogenes isolated were moderately resistant to erythromycin and highly but paradoxically resistant to lincomycin, and they showed antagonism between the two antibiotics. Another strain was moderately resistant to erythromycin and sensitive to lincomycin, and it showed synergism between the two antibodies.
D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D004917:Erythromycin / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D008034:Lincomycin / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D013045:Species Specificity; D013297:Streptococcus pyogenes / Q000187:drug effects*
D004917:Erythromycin; D008034:Lincomycin