title: Experience with the use of proteolytic enzyme (Travase) in burn patients.
abstract: In an effort to find an enzyme preparation for chemical debridement of burns, we treated 463 burn patients with Sutilains ointment (Travase) from 1972 through 1975. This method allowed earlier application of the first skin graft and resulted in a shorter hospital stay without significantly altering mortality compared with results obtained before 1972 and with national results. Travase appears to be effective in the treatment of burn patients when used in this method.
mesh_terms: D000328:Adult; D002056:Burns / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D003646:Debridement; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D010447:Peptide Hydrolases / Q000627:therapeutic use*; D012837:Silver Sulfadiazine / Q000627:therapeutic use
chemical_list: D010447:Peptide Hydrolases; D012837:Silver Sulfadiazine