[Further study of the hormonal regulation of natural immunity to weak transplantation antigens in inbred mice].
Blood plasma corticosterone level and the extent of immunological reaction to sex-antigen of skin transplant in inbred mice CBA, C57Bl/6, F1 (CBA X 57Bl/6), C3H, AKR was compared. Mice CBA had a high blood plasma corticosterone level and no immunological reaction to sex-antigen. A lower blood corticosterone level and the presence of reaction to sex-antigen was characteristic of mice C57Bl/6, AKR, C3H, F1(CBA X C57Bl/6). The number of endogenous colonies in the spleen of mice CBA was less than in mice C57Bl/6. Mice CBA had a narrow cortical thymus layer in comparison with the wide thymus cortex of mice AKR and C57Bl/6. Adrenalectomy of mice CBA caused a sharp widening of the thymus cortex.
D000315:Adrenalectomy; D000818:Animals; D000937:Antigen-Antibody Reactions; D002999:Clone Cells / Q000166:cytology; D003345:Corticosterone / Q000097:blood*; D005260:Female; D006649:Histocompatibility Antigens; D007113:Immunity, Innate; D008297:Male; D051379:Mice; D008806:Mice, Inbred AKR; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008815:Mice, Inbred Strains / Q000276:immunology*; D016038:Skin Transplantation; D013154:Spleen / Q000166:cytology; D013950:Thymus Gland / Q000166:cytology
D006649:Histocompatibility Antigens; D003345:Corticosterone
Dal'neĭshee izuchenie gormonal'noĭ reguliatsii estestvennogo immuniteta k slabym transplantatsionnym antigenam u inbrednykh mysheĭ.