title: Bacterial studies of leg ulcers.
abstract: --Bacteriologic studies of 30 chronic leg ulcers were studied in 18 adult patients before and after treatment with a local cleansing agent, Debrisan.--Results show that all ulcers, whether clinically inflamed or not, are secondarily infected.--The majority of ulcers grew more than 1 type of organism, up to 6 different types in 1 single ulcer.--The use of Debrisan reduces the types of organisms and colony counts in ulcers, allowing healthy granulation and epithelialization to proceed normally.--Control of infection reduces surrounding local edema and erythema.--By reducing types of organisms and colony counts in chronic leg ulcers successful skin grafting was readily achieved.
mesh_terms: D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000150:complications* / Q000188:drug therapy; D003911:Dextrans / Q000627:therapeutic use; D004811:Epichlorohydrin / Q000627:therapeutic use; D006801:Humans; D007871:Leg Ulcer / Q000150:complications* / Q000188:drug therapy / Q000628:therapy; D008875:Middle Aged; D016038:Skin Transplantation; D014184:Transplantation, Homologous
chemical_list: D003911:Dextrans; D004811:Epichlorohydrin; C013471:dextranomer