[Effects of anesthesia and surgical trauma on the immune response of pediatric patients].
The AA. have evaluated the effects of anaesthesia and surgical trauma on the ability of lymphocytes from 10 patients to release Leukocyte Inhibiting Factor (LIF) after stimulation with phytohaemoagglutinin (PHA). In addition, they have studied the electrophoretic mobility of Polymorphonuclear-cells (PMN) and lymphocytes of 8 patients after incubation in autologus plasma. The experimental results show decrease of LIF production after operation in 6 individuals and reduction of eletrophoretic mobility of PMN and lymphocytes. The last finding is not significant on statistical point of view.
D000293:Adolescent; D000758:Anesthesia / Q000009:adverse effects*; D002464:Cell Migration Inhibition; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D037102:Lectins / Q000494:pharmacology; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D008263:Macrophage Migration-Inhibitory Factors / Q000378:metabolism; D008297:Male; D013514:Surgical Procedures, Operative / Q000009:adverse effects*
D037102:Lectins; D008263:Macrophage Migration-Inhibitory Factors
Effetti della anestesia e del trauma operatorio sulla risposta immunitaria di pazienti in eta' pediatrica.