Metastatic osteomyelitis following BCG vaccination.
An 8-year-old girl, who had been vaccinated with BCG without subsequent regional reactions, developed osteomyelitis in the left calcaneus 7 months later. The process healed after surgical treatment and chemotherapy for 1 year. Culture from the bone abscess gave growth of mycobacteria which could not be distinguished from BCG.
D000038:Abscess / Q000139:chemically induced* / Q000188:drug therapy / Q000382:microbiology; D001500:BCG Vaccine / Q000009:adverse effects*; D002111:Calcaneus / Q000473:pathology*; D002648:Child; D004917:Erythromycin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D009163:Mycobacterium bovis / Q000302:isolation & purification; D010019:Osteomyelitis / Q000139:chemically induced* / Q000188:drug therapy / Q000382:microbiology; D013307:Streptomycin / Q000627:therapeutic use
D001500:BCG Vaccine; D004917:Erythromycin; D007538:Isoniazid; D013307:Streptomycin