Uteroglobin-like antigen in the pulmonary epithelium and secretion of the lung.
The immunological identity of a uteroglobin-like protein, occurring in respiratory tract secretions and tissue, with uteroglobin from rabbit endometrial secretion is demonstrated. A uteroglobin-like antigen has been localized in bronchial epithelial cells and in bronchioles by immunofluorescence. This secretory protein is, in contrast to the authentic uteroglobin, hormone-independent, as far as estrogens and progesterone are concerned. The possible significance of comparative studies on uteroglobin and the uteroglobin-like antigen is discussed, taking into account cytological, endocrinological, and molecularbiological aspects.
D000818:Animals; D000941:Antigens / Q000032:analysis*; D001980:Bronchi / Q000276:immunology*; D003429:Cross Reactions; D004717:Endometrium / Q000276:immunology; D004848:Epithelium / Q000276:immunology; D005260:Female; D005455:Fluorescent Antibody Technique; D006023:Glycoproteins / Q000276:immunology*; D007122:Immunoelectrophoresis; D008297:Male; D011817:Rabbits; D013183:Sputum / Q000276:immunology*; D014598:Uteroglobin / Q000276:immunology*
D000941:Antigens; D006023:Glycoproteins; D014598:Uteroglobin