A comparison of noxythiolin and povidone-iodine in experimentally induced peritoneal infection in mice.
Noxythiolin (Noxyflex, Geistlich), given intraperitoneally as a 2.5 per cent solution, protected mice from the lethal effects of an intraperitoneal injection of Escherichia coli. Povidone-iodine (Pevidine, Berk), containing 0.075 per cent iodine, gave no protection.
D000818:Animals; D004926:Escherichia coli; D007274:Injections, Intraperitoneal; D008297:Male; D051379:Mice; D009677:Noxythiolin / Q000008:administration & dosage / Q000627:therapeutic use*; D010538:Peritonitis / Q000188:drug therapy* / Q000209:etiology; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000008:administration & dosage / Q000627:therapeutic use*; D013890:Thiourea / Q000031:analogs & derivatives*
D009677:Noxythiolin; D011206:Povidone-Iodine; D011205:Povidone; D013890:Thiourea