Metastatic malignant melanoma transplanted via a renal homograft: a case report.
A case of transplantation of a malignant melanoma via a cadaver renal homograft is presented. The recipient developed a widespread malignancy ninteen months after renal transplantation. At autopsy the tumor was diagnosed as a malignant melanoma. Autopsy of the donor had previously revealed a spindle cell malignancy in the spleen. It is postulated that the splenic tumor in the donor represents a spindle cell variant of malignant melanoma, and hence this malignancy was inadvertently transferred to the recipient via the renal homograft.
D002102:Cadaver; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D007680:Kidney Neoplasms / Q000209:etiology* / Q000473:pathology; D016030:Kidney Transplantation; D008297:Male; D008545:Melanoma / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D013160:Splenic Neoplasms / Q000473:pathology; D014184:Transplantation, Homologous