Immune complexes in myelofibrosis: a possible guide to management.
Using a fluorescent technique intracellular immune complexes were found in the peripheral leucocytes in all of 12 patients with myelofibrosis studied. Fluorescent cells varied from 12% to 81%; with no relation to the total white count or any obvious clinical finding. Three of the patients with severe refractory anaemia benefited from immunosuppressive therapy.
D000936:Antigen-Antibody Complex; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007962:Leukocytes / Q000276:immunology; D008297:Male; D055728:Primary Myelofibrosis / Q000276:immunology* / Q000628:therapy
D000936:Antigen-Antibody Complex