title: [Problems in massive transfusion].
abstract: The concept of massive blood transfusion is defined not by the number of units of blood administered but rather by the relationship of the number of blood units transfused to the normal blood volume of the recipient and the rapidity of administration. The composition of stored blood can lead to different metabolic disturbances, specifically in cases of massive transfusion. The importance of hyperkalemia, hypocalcemia and citrate intoxication as well as disturbances in the acid-base balance and blood coagulation as seen in cases of massive transfusion are analysed and the necessary therapeutical consequences discussed.
mesh_terms: D000137:Acid-Base Imbalance / Q000209:etiology; D001639:Bicarbonates / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000209:etiology; D001779:Blood Coagulation Factors / Q000032:analysis; D001793:Blood Preservation; D001794:Blood Pressure; D001803:Blood Transfusion; D001810:Blood Volume; D002118:Calcium / Q000009:adverse effects / Q000627:therapeutic use; D002951:Citrates / Q000506:poisoning; D006493:Heparin; D006801:Humans; D006996:Hypocalcemia / Q000517:prevention & control; D007008:Hypokalemia / Q000209:etiology; D012881:Skin Temperature; D012964:Sodium / Q000627:therapeutic use; D014690:Venous Pressure; D014693:Ventricular Fibrillation / Q000139:chemically induced
chemical_list: D001639:Bicarbonates; D001779:Blood Coagulation Factors; D002951:Citrates; D006493:Heparin; D012964:Sodium; D002118:Calcium
vernacular_title: Probleme bei der Massivtransfusion.