Role of the intrinsic metal in RNA polymerase from Escherichia coli. In vivo substitution of tightly bound zinc with cobalt.
D003035:Cobalt / Q000494:pharmacology*; D012321:DNA-Directed RNA Polymerases / Q000302:isolation & purification / Q000378:metabolism; D004926:Escherichia coli / Q000201:enzymology*; D007700:Kinetics; D013053:Spectrophotometry; D013698:Templates, Genetic; D015032:Zinc / Q000494:pharmacology
D003035:Cobalt; D012321:DNA-Directed RNA Polymerases; D015032:Zinc