[Neutrophil function in children with acute lyphoblastic leukemia].
Neutrophil function has been studied in 12 patients with acute lymphoblastic leukemia by means of the NBT test and bactericidal assay against E. coli. Tests have been performed before and during treatment. In untreated patients the bactericidal activity of neutrophils was normal, in spite of the decreased number of cells reducing the NBT dye after activation with immuno-complexes. In remission, those patients showed normal reduction. No correlation was observed between the bactericidal power registered after cranial irradiation and the NBT test.
D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use; D001770:Blood Bactericidal Activity / Q000187:drug effects / Q000528:radiation effects; D002648:Child; D002675:Child, Preschool; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D004926:Escherichia coli; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000276:immunology* / Q000532:radiotherapy; D008297:Male; D009504:Neutrophils; D009580:Nitroblue Tetrazolium
D000970:Antineoplastic Agents; D003037:Cobalt Radioisotopes; D009580:Nitroblue Tetrazolium
La funzione dei neutrofili nel bambino con leucemia linfoblastica acuta.