[Inhibition of tumor growth and metastases in mice with Lewis lung tumors by vitamin A and BCG].
The anti-tumor effect of vitamin A and/or BCG was investigated in Lewis lung tumor system. Tumor growth and lung metastases were significantly suppressed, when tumor cells were mixed with BCG and inoculated subcutaneously into vitamin A-treated animals. Survival time was also prolonged by the same treatment. Vitamin A alone, without BCG, showed no effect on tumor growth, lung metastases or survival time.
D000818:Animals; D001500:BCG Vaccine; D008175:Lung Neoplasms / Q000628:therapy*; D008297:Male; D051379:Mice; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D014801:Vitamin A / Q000627:therapeutic use*
D001500:BCG Vaccine; D014801:Vitamin A
Hemmung von Tumorwachstum und Metastasen in Lewis-Lungentumortragenden Mäusen durch Vitamin A+BCG.