Regulation of polyamine and streptomycin transport during stringent and relaxed control in Escherichia coli.
Inhibition of polyamine uptake was observed during amino acid depletion in a stringent strain of Escherichia coli CP78 but not in a relaxed strain (CP79). Chloramphenicol was shown partially to relieve the inhibition of uptake. Stringent cells which were induced for a transport system common to both polyamines and streptomycin were found to restrict the uptake of spermidine as well as streptomycin.
D000596:Amino Acids / Q000494:pharmacology; D001693:Biological Transport, Active / Q000187:drug effects; D002701:Chloramphenicol / Q000494:pharmacology; D003470:Culture Media; D004926:Escherichia coli / Q000378:metabolism*; D006150:Guanine Nucleotides / Q000378:metabolism*; D006159:Guanosine Tetraphosphate / Q000378:metabolism*; D011700:Putrescine / Q000378:metabolism*; D013095:Spermidine / Q000378:metabolism*; D013307:Streptomycin / Q000378:metabolism*
D000596:Amino Acids; D003470:Culture Media; D006150:Guanine Nucleotides; D006159:Guanosine Tetraphosphate; D002701:Chloramphenicol; D013095:Spermidine; D011700:Putrescine; D013307:Streptomycin