[Effect of L-DOPA administration on brain bioelectrical activity in hypothalamo-hypophyseal diseases].
The influence of the L-DOPA preparation on the bioelectrical activity of the brain was studied in 15 patients with Itsenko-Cushing's disease and in 12 patients with diencephalic obesity. L-DOPA administration caused an increase of the theta-rhythm index in the anterior leads in comparison with the initial recording, although the periods of detection of this elevation differed in various patients. No changes of the character of the EEG recording during the test with L-DOPA in comparison with the background recording was revealed in the patients with Itsenko-Cushings disease.
D000293:Adolescent; D000328:Adult; D000513:Alpha Rhythm; D001921:Brain / Q000187:drug effects*; D001927:Brain Diseases / Q000188:drug therapy* / Q000503:physiopathology; D002986:Clinical Trials as Topic; D003480:Cushing Syndrome / Q000188:drug therapy; D004027:Diencephalon; D004341:Drug Evaluation; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007031:Hypothalamus; D007980:Levodopa / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000188:drug therapy; D010900:Pituitary Diseases / Q000188:drug therapy* / Q000503:physiopathology; D013826:Theta Rhythm; D013997:Time Factors
D007980:Levodopa
Vliianie vvedeniia L-DOFA na bioélektricheskuiu aktivnost' golovnogo mozga bol'nykh s gipotalamo-gipofizarnymi zabolevaniiami.