title: Fibrous reactions in the tissues which surround silicone breast prostheses.
abstract: Fibrotic reactions in adipose tissue, in the pectoral muscle and in the mammary gland are described. These were provoked by trauma to those tissues during implantation. Such reactions cause thickening of the capsule around the implant, and may be contributory factors in constrictive fibrosis.
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D001940:Breast / Q000473:pathology / Q000601:surgery*; D005260:Female; D005549:Foreign-Body Reaction / Q000473:pathology; D006801:Humans; D010369:Pectoralis Muscles / Q000473:pathology; D019736:Prostheses and Implants / Q000009:adverse effects*; D012828:Silicones / Q000009:adverse effects
chemical_list: D012828:Silicones