[Use of cardiotonic heterosides in pediatrics].
The indications for the administration of cardiotonic heterosides are quite similar in adults and children. However, their use in children raises several practical problems, generally related to differences in kinetics and/or tissular sensitivity. The pharmacodynamic properties and the kinetics of cardiotonic glycosides of digitalis are reviewed and therapeutic and toxicologic effects are discussed.
D000367:Age Factors; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D002648:Child; D004071:Digitalis Glycosides / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology / Q000506:poisoning / Q000627:therapeutic use*; D006329:Heart Conduction System / Q000187:drug effects; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D009200:Myocardial Contraction / Q000187:drug effects; D009206:Myocardium / Q000378:metabolism
D004071:Digitalis Glycosides
L'utilisation des heterosides cardiotoniques en pediatrie.