Mapping of the two mitochondrial antimycin A resistance loci in Saccharomyces cerevisiae.
Retention or loss of the two new mitochondrial antimycin A resistance loci AI and AII has been analyzed in a large number of stable cytoplasmic petite mutants. Using these deletion mutants it was possible to localize the two antimycin A resistance loci in the OI--OII region of mitochondrial DNA. The genetic loci are mapped in the following order: OII--AI--AII--cobl--OI. The mapping relationship of mutants resistant to antimycin A or funiculosin to various cob mutants is described.
D000968:Antimycin A / Q000494:pharmacology*; D004272:DNA, Mitochondrial; D004352:Drug Resistance, Microbial; D005111:Extrachromosomal Inheritance; D005796:Genes; D008040:Genetic Linkage; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics*
D004272:DNA, Mitochondrial; D000968:Antimycin A