title: Effect of an acute dose of ethanol on rat liver microsomal mixed function oxygenase components and membrane lipid composition.
abstract: The lipid composition of rat liver microsomes was not altered in response to a single acute dose of ethanol relative to isocaloric glycerol-treated controls. Microsomal cytochrome P-450 was transiently elevated, the elevation paralleling blood ethanol levels. Microsomal NADPH oxidase was transiently elevated relative to the activity in isocaloric glycerol-treated controls.
mesh_terms: D000818:Animals; D000431:Ethanol / Q000097:blood / Q000494:pharmacology*; D005227:Fatty Acids / Q000378:metabolism; D008099:Liver / Q000187:drug effects; D008297:Male; D008563:Membrane Lipids / Q000378:metabolism*; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D009929:Organ Size / Q000187:drug effects; D010088:Oxidoreductases / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
chemical_list: D005227:Fatty Acids; D008563:Membrane Lipids; D000431:Ethanol; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases