A trial of Lotussin and linctus diphenhydramine in patients wth an irritant cough.
Lotussin and linctus diphenhydramine were compared for efficacy and patient preference in fifty patients suffering from post-infective cough. The trial was a single-blind randomized crossover one which was subjected to sequential analysis based on patient preferences. Under the conditions of the trial there appeared to be a significant difference in favour of Lotussin (p less than 0-01).
D000643:Ammonium Chloride / Q000627:therapeutic use; D000996:Antitussive Agents / Q000627:therapeutic use*; D002725:Chloroform / Q000627:therapeutic use; D002951:Citrates / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003371:Cough / Q000188:drug therapy*; D003915:Dextromethorphan / Q000627:therapeutic use; D004155:Diphenhydramine / Q000627:therapeutic use; D004338:Drug Combinations; D004341:Drug Evaluation; D004809:Ephedrine / Q000627:therapeutic use; D006140:Guaifenesin / Q000627:therapeutic use; D006801:Humans; D008610:Menthol / Q000627:therapeutic use
D000996:Antitussive Agents; D002951:Citrates; D004338:Drug Combinations; D000643:Ammonium Chloride; D008610:Menthol; D006140:Guaifenesin; D003915:Dextromethorphan; D002725:Chloroform; D004155:Diphenhydramine; D004809:Ephedrine