Biochemical analysis of damage induced in yeast by formaldehyde. II. Induction of cross-links between DNA and protein.
Exposure of Saccharomyces cerevisiae cells to formaldehyde-induced cross-links between DNA and proteins. This damage was demonstrated by three different techniques. Ultraviolet irradiation also produced cross-links between DNA and proteins in yeast.
D002499:Centrifugation, Density Gradient; D004247:DNA / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005557:Formaldehyde / Q000494:pharmacology*; D005656:Fungal Proteins / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics* / Q000528:radiation effects; D014466:Ultraviolet Rays
D005656:Fungal Proteins; D005557:Formaldehyde; D004247:DNA