Mutagenic activity of furfural in Salmonella typhimurium TA100.
The mutagenic activity of furfural was tested in Salmonella typhimurium strains TA98 and TA100. Furfural produced mutations in the TA100 strain, but not in the TA98 strain. A rat-liver microsomal fraction did not increase the mutagenic activity of furfural in either strain. Mutagenic activity of furfural in the TA100 strain was not increased by benzo[alpha]pyrene in the presence of metabolic activation.
D001580:Benzopyrenes / Q000494:pharmacology; D001711:Biotransformation; D005662:Furaldehyde / Q000494:pharmacology*; D005821:Genetic Techniques; D009153:Mutagens; D012486:Salmonella typhimurium / Q000235:genetics
D001580:Benzopyrenes; D009153:Mutagens; D005662:Furaldehyde