title: Neuro-insular complex type I in the mouse. Re-evaluation of the pancreatic islet as a modified ganglion.
abstract: Autonomic ganglia in the pancreas may include islet cells; while islets sometimes contain a group of ganglion cells. Electron microscope observation in adult mice confirms occurrence of a structure called neuro-insular complex type I by Fujita (1959), in which islet cells are juxtaposed to nerve cells either directly or by intercalation of a thin glial cell cytoplasm. Islet cells are equivalent to neurons in their attitude towards neurons and towards glial elements in the neuro-insular complex. There seems to be every gradation between pure ganglia, mixed forms representing the neuro-insular complexes, and pure islets. Pancreatic islets may thus be regarded as modified ganglia.
mesh_terms: D000818:Animals; D005260:Female; D005725:Ganglia, Autonomic / Q000648:ultrastructure*; D007515:Islets of Langerhans / Q000648:ultrastructure*; D008297:Male; D051379:Mice; D010179:Pancreas / Q000294:innervation*