Experimental and clinical data indicating the psychotropic properties of progestogens.
Investigations of the psychotropic effects of progestogens employing the technique of quantitative pharmaco-EEG indicated that progestogens produce a profile similar to that of the minor tranquillizers. Healthy volunteers received single oral doses in a double-blind controlled study. A short review of the clinical literature adds support to the suggestion that progestogens have sedative properties.
D001519:Behavior / Q000187:drug effects; D002490:Central Nervous System / Q000187:drug effects*; D002540:Cerebral Cortex / Q000187:drug effects; D002986:Clinical Trials as Topic; D003534:Cyproterone / Q000494:pharmacology; D003975:Diazepam / Q000494:pharmacology; D004311:Double-Blind Method; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008598:Menstruation; D009644:Norgestrel / Q000494:pharmacology; D011247:Pregnancy; D045167:Progesterone Congeners / Q000494:pharmacology*
D045167:Progesterone Congeners; D009644:Norgestrel; D003534:Cyproterone; D003975:Diazepam