title: Midbrain central gray: LHRH infusion enhances lordotic behavior in estrogen-primed ovariectomized rats.
abstract: Ovariectomized rats were implanted with 23 gauge stainless steel cannulae in the ventrolateral midbrain central gray. Twelve sexually active rats were estrone-primed and infused with saline and 50 ng luteinizing hormone-releasing hormone (LHRH) in counterbalanced order. Infusion of luteinizing hormone-releasing hormone significantly enhanced the lordotic response to coital stimulation compared to saline infusion. These results support the role of hypothalamo-mesencephalic LHRH-containing pathways in modulating lordotic behavior in estrogen-primed ovariectomized rats.
mesh_terms: D000818:Animals; D002369:Castration; D004970:Estrone / Q000494:pharmacology*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D007031:Hypothalamus / Q000187:drug effects; D008636:Mesencephalon / Q000187:drug effects*; D011374:Progesterone / Q000494:pharmacology; D051381:Rats; D012726:Sexual Behavior, Animal / Q000187:drug effects*
chemical_list: D004970:Estrone; D007987:Gonadotropin-Releasing Hormone; D011374:Progesterone