Evidence for changes in cell shape from a 2-dimensional to a 3-dimensional substrate.
Chick embryo mesoderm cells were explanted to culture systems in vivo and in vitro and their subsequent movements were correlated with the external morphology as studied by SEM. In vitro cell movements are exaggerations of normal in vivo movements where a 2-dimensional substrate is encountered rather than a 3-dimensional environment.
D000818:Animals; D002465:Cell Movement; D002642:Chick Embryo; D003584:Cytological Techniques; D008648:Mesoderm / Q000166:cytology*; D008855:Microscopy, Electron, Scanning