The role of enteropeptidase in the digestion of protein and its development in human fetal small intestine.
Enteropeptidase converts trypsinogen into active trypsin, which not only hydrolyses some peptide bonds of food proteins but also activates a number of pancreatic zymogens. For this reason enteropeptidase is a key enzyme in the digestion of dietary proteins and its absence may result in gross protein malabsorption.
D000595:Amino Acid Sequence; D000818:Animals; D002648:Child; D004044:Dietary Proteins; D004063:Digestion; D010450:Endopeptidases / Q000378:metabolism*; D004765:Enteropeptidase / Q000172:deficiency / Q000378:metabolism*; D004789:Enzyme Activation; D005260:Female; D005333:Fetus / Q000378:metabolism; D005865:Gestational Age; D006801:Humans; D007421:Intestine, Small / Q000196:embryology / Q000201:enzymology*; D008871:Microvilli / Q000201:enzymology; D011247:Pregnancy; D013045:Species Specificity; D014357:Trypsin / Q000378:metabolism; D014362:Trypsinogen / Q000378:metabolism
D004044:Dietary Proteins; D014362:Trypsinogen; D010450:Endopeptidases; D014357:Trypsin; D004765:Enteropeptidase