[Fetal macrosomy in alloxanized rats (author's transl)].
The aim of this work was to observe the starting of fetal macrosomy during the gestation of the diabetic rat and whether the sex of the fetuses has any influence on it. Lesions were produced in the B cells of the pancreas by the administration of alloxan on the 4th gestation day. The length and weight of the fetuses were not altered by this treatment before the 14th day of pregnancy, suggesting that fetal macrosomy should occur after this day.
D000496:Alloxan / Q000008:administration & dosage; D000818:Animals; D001835:Body Weight; D003921:Diabetes Mellitus, Experimental / Q000150:complications / Q000503:physiopathology*; D005260:Female; D005315:Fetal Diseases / Q000209:etiology* / Q000503:physiopathology; D007328:Insulin / Q000008:administration & dosage; D007515:Islets of Langerhans / Q000187:drug effects; D008297:Male; D010179:Pancreas / Q000473:pathology; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000150:complications / Q000503:physiopathology*; D051381:Rats; D012737:Sex Factors
D007328:Insulin; D000496:Alloxan
Macrossomia em fetos de ratas aloxanizadas.