[Experiences with research on pharmacopsychological effects on older people].
During the last years we tested a number of cerebral vasoactive and cerebral metabolic active substances on aged people with the help of the double blind method against with placebo in order to measure the change of the "nutritive insufficiency" with its neurophysiological and vascular-psychological syndromes under pharmacological influence. We used psychological test instruments (groups of 60-80 patients between 50 and 70 years). Duration of the treatment was 3-4 months. Analysis of the dates by way of variance and covariance analysis. Significant results of successive treatments were achieved: improvements of the mental ability as far as the functions of the memory are concerned, higher capacity of attention and concentration (vigilance), fluency and adaptability of cognitive functions, increasing openess of mind and the ability of experiencing, improvement of the general mood and good health. Longer lasting effects in comparison of the drugs were noticed only after treatment with metabolic agents. Publication is planned.
D000368:Aged; D001288:Attention / Q000187:drug effects; D002986:Clinical Trials as Topic; D003071:Cognition / Q000187:drug effects; D004311:Double-Blind Method; D004644:Emotions / Q000187:drug effects; D006801:Humans; D008568:Memory / Q000187:drug effects; D008606:Mental Processes / Q000187:drug effects*; D008875:Middle Aged; D011581:Psychological Tests; D012392:Rorschach Test; D013997:Time Factors; D014665:Vasodilator Agents / Q000494:pharmacology*
D014665:Vasodilator Agents
Erfahrungen bei der Untersuchung pharmakopsychologischer Effekte im Alter.