The ability of cholestyramine resin and other adsorbents to bind Escherichia coli enterotoxins.
Several adsorbent materials were evaluated for their ability to bind Escherichia coli enterotoxins. Cholestyramine, a strong anion-exchange resin, bound the heat-labile and the heat-stable types of enterotoxin and reduced significantly their effects in some animal models. However, its efficacy in the treatment of diarrhoeic piglets appeared to be adversely affected by the presence of milk in the alimentary tract.
D000327:Adsorption; D000818:Animals; D001427:Bacterial Toxins / Q000378:metabolism*; D002792:Cholestyramine Resin / Q000378:metabolism* / Q000627:therapeutic use; D003967:Diarrhea / Q000188:drug therapy; D004768:Enterotoxins / Q000378:metabolism*; D004926:Escherichia coli; D007408:Intestinal Absorption; D008892:Milk; D013552:Swine
D001427:Bacterial Toxins; D004768:Enterotoxins; D002792:Cholestyramine Resin