title: Atropine versus glycopyrrolate. A study of intraocular pressure and pupil size in man.
abstract: Following control observations of intraocular pressure and pupil size, in doses suitable for pre-anaesthetic medication, glycopyrrolate (0.004 mg/kg) and atropine (0.01 mg/kg) were given intramuscularly to healthy volunteers in a randomised, cross-over fashion. No significant change in either intraocular pressure or pupil size was noted 45 min after drug administration.
mesh_terms: D000328:Adult; D001285:Atropine / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D006024:Glycopyrrolate / Q000494:pharmacology*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008875:Middle Aged; D011229:Preanesthetic Medication; D011680:Pupil / Q000187:drug effects*; D011759:Pyrrolidines / Q000494:pharmacology*; D011897:Random Allocation; D012107:Research Design
chemical_list: D011759:Pyrrolidines; D001285:Atropine; D006024:Glycopyrrolate