Preparation and characterization of insulin of carp (Cyprinus carpio).
Insulin of carp (Cyprinus carpio) was isolated and crystallized. The insulin was biologically active in two tests; it decreased the blood glucose level and stimulated 14CO2-formation from glucose. The chemical properties are similar to those of insulins from other species. The insulins of carp and of mammals differ greatly immunologically. Antibodies against carp insulin crossreact with carp proinsulin.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002245:Carbon Dioxide / Q000378:metabolism; D002347:Carps; D002417:Cattle; D003429:Cross Reactions; D003530:Cyprinidae; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000032:analysis / Q000276:immunology / Q000302:isolation & purification / Q000494:pharmacology; D007330:Insulin Antibodies / Q000276:immunology; D007515:Islets of Langerhans / Q000032:analysis; D011384:Proinsulin / Q000276:immunology; D051381:Rats
D000596:Amino Acids; D001786:Blood Glucose; D007328:Insulin; D007330:Insulin Antibodies; D002245:Carbon Dioxide; D011384:Proinsulin; D005947:Glucose