title: Comparative trial of a new hypnotic (Finorgal) with nitrazepam and triclofos sodium.
abstract: Thirty patients complaining of insomnia were studied in a double-blind trial with crossover of Finorgal, nitrazepam and triclofos sodium. Finorgal given as a hypnotic produced similar results to nitrazepam and triclofos sodium in terms of induction of sleep, duration and quality of sleep, dream recall and morning 'hangover'. Reported side-effects were not serious and occurred less frequently in association with Finorgal treatment than with nitrazepam or triclofos sodium. Laboratory investigations gave no indication of the development of any drug toxicity during the three-week period of the trial.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D002214:Capsules; D002986:Clinical Trials as Topic; D004155:Diphenhydramine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004311:Double-Blind Method; D004338:Drug Combinations; D004984:Ethchlorvynol / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005023:Ethylene Chlorohydrin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009567:Nitrazepam / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D009943:Organophosphorus Compounds / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy*
chemical_list: D002214:Capsules; D004338:Drug Combinations; D006993:Hypnotics and Sedatives; D009943:Organophosphorus Compounds; D004984:Ethchlorvynol; D005023:Ethylene Chlorohydrin; C022230:finorgal; D004155:Diphenhydramine; D009567:Nitrazepam