Healing of duodenal ulcer during treatment with an anticholinergic and an antacid.
Twenty-nine patients with endoscopically proven duodenal ulcers were treated with either placebo or benzilonium bromide (Ulcoban prolongatum) for 4 weeks. Antacid consumption was low in both groups. Healing after 4 weeks was verified endoscopically and was about equal for both treatments. Frequency of pain and other "dyspeptic" symptoms appeared to be less in patients treated with benzilonium. Lack of symptoms was not always associated with healing of the ulcers.
D000863:Antacids / Q000627:therapeutic use*; D001561:Benzilates / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy*; D006801:Humans; D010276:Parasympatholytics; D010919:Placebos; D011759:Pyrrolidines / Q000627:therapeutic use*
D000863:Antacids; D001561:Benzilates; D010276:Parasympatholytics; D010919:Placebos; D011759:Pyrrolidines