title: Small-colony forms of enteric bacteria after exposure to aminoglycosides.
abstract: Small colony forms of enteric bacteria were isolated in vitro after exposure of near-lethal amounts of aminoglycosides. These small-colony forms were several times more resistant to all aminoglycosides than the parent clones. A small form of Escherichia coli was isolated directly from a clinical specimen, along with a more sensitive larger colony.
mesh_terms: D000617:Aminoglycosides / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D004926:Escherichia coli / Q000187:drug effects / Q000302:isolation & purification; D005839:Gentamicins / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D008826:Microbial Sensitivity Tests
chemical_list: D000617:Aminoglycosides; D005839:Gentamicins