title: Properties of anti-hairy cell serum.
abstract: An antiserum was prepared in rabbits against hairy leukaemic cells. After absorption with human erythrocytes, thymus and liver powder, the serum was passed through immunoabsorbent columns to remove extensive anti-plasma protein activity. Following these procedures, sensitive techniques failed to reveal residual activity against alpha-macroglobulins, beta2-microglobulin and other human plasma proteins. The antiserum reacted with normal B lymphocytes but not with T lymphocytes or monocytes. Positive reactions were seen in B cell lymphomas, chronic lymphocytic leukaemia, hairy-cell leukaemia and uninucleated Reed-Sternberg cells.
mesh_terms: D001402:B-Lymphocytes / Q000276:immunology; D005455:Fluorescent Antibody Technique; D006689:Hodgkin Disease / Q000276:immunology / Q000648:ultrastructure; D006801:Humans; D007106:Immune Sera / Q000276:immunology*; D007943:Leukemia, Hairy Cell / Q000276:immunology* / Q000648:ultrastructure; D007945:Leukemia, Lymphoid / Q000276:immunology; D008223:Lymphoma / Q000276:immunology; D008854:Microscopy, Electron
chemical_list: D007106:Immune Sera