[Enhanced UV sensitivity of Escherichia coli strain uvrA crp].
UV-sensitivity and UV-induced mutability to tryptophan independence has been studied in isogenic crp, cya, crp+, uvrA crp and uvrA crp+ strains of Escherichia coli. crp and cya strains are found to have the same UV-sensitivity as an isogenic wild type strain. UV-sensitivity of uvrA crp strain seems to be one-two orders increased as compared with the sensitivity exhibited by the uvrA - crp+ strain. The yield of UV-induced revertants is slightly higher in crp, cya and uvrA crp strains than in the wild type cells. The existence of cap-dependent inducible error-free repair pathway is supposed due to the data obtained.
D004260:DNA Repair / Q000528:radiation effects; D004269:DNA, Bacterial / Q000528:radiation effects; D004926:Escherichia coli / Q000235:genetics / Q000528:radiation effects*; D005796:Genes / Q000528:radiation effects; D009154:Mutation; D014466:Ultraviolet Rays
D004269:DNA, Bacterial
Povyshennaia UF-chuvstvitel'nost' shtamma Escherichia coli uvrA crp.