Hypothalamic monoamine contents in endotoxin fever of new-born guinea pigs and kittens.
In new-born guinea pigs and kittens Escherichia coli endotoxin did not significantly modify the hypothalamic level of either norepinephrine (NE) or 5-hydroxytryptamine (5-HT). The hypothalamic 5-hydroxyindoleacetic acid (5-HIAA) content was significantly elevated in endotoxin-treated animals, but this elevation was confined to a period following the endotoxin injections by about 60 min in guinea pigs and 75-90 min in kittens.
D000818:Animals; D001679:Biogenic Amines / Q000032:analysis*; D002415:Cats; D004731:Endotoxins / Q000506:poisoning*; D004926:Escherichia coli; D005334:Fever / Q000139:chemically induced / Q000378:metabolism*; D006168:Guinea Pigs; D006897:Hydroxyindoleacetic Acid / Q000032:analysis; D007031:Hypothalamus / Q000032:analysis*; D009638:Norepinephrine / Q000032:analysis; D012701:Serotonin / Q000032:analysis; D013045:Species Specificity; D013997:Time Factors
D001679:Biogenic Amines; D004731:Endotoxins; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D009638:Norepinephrine