title: [Various considerations in the treatment of amebic liver abscess].
abstract: From 1974 to 1976 Acute Amoebic Hepatic Abscess treatment was viewed retrospectively with a random double blind prospective study administering metronidazol emetine, or a combination of both to three groups of 20 patients per group. The retrospective study of 1974 underlines the then predominant tendency toward a surgical management with a higher mortality (p less than 0.002). In 1976 medical treatment patients increased with a corresponding diminution of mortality (p less than 0.001). The prospective study showed no statistically significant response difference to the pharmacologic treatment variations. Here only 1.6% of patients underwent surgery and 1/3 of them received puncture drainage due to medical treatment failure. We conclude that non complicated acute amoebic liver abscess treatment should be medical, preferably with only one antiamoebic drug.
mesh_terms: D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004341:Drug Evaluation; D004640:Emetine / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007273:Injections, Intramuscular; D008101:Liver Abscess, Amebic / Q000188:drug therapy*; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use*; D010919:Placebos
chemical_list: D010919:Placebos; D008795:Metronidazole; D004640:Emetine
vernacular_title: Algunas consideraciones en el tratamiento del absceso hepático amibiano.