An inducible proline transport system in Candida albicans.
1. When Candida albicans cells were preincubated with proline or grown in the presence of proline as the sole nitrogen source they exhibited a rapid increase in the influx of proline (the inducible transport system). 2. The induction appeared to be specific for proline and also demonstrated in other Candida species. 3. Both the inducible and constitutive proline uptake systems exhibited similar characteristic features. 4. The nature of the inducer for proline uptake in C. albicans appeared to be free proline. 5. The development of the inducible proline transport system was dependent on concomitant synthesis of RNA and protein and the induction was not affected by glucose or any other carbon sources used.
D000596:Amino Acids / Q000378:metabolism; D001692:Biological Transport; D002176:Candida albicans / Q000378:metabolism*; D006601:Hexoses / Q000378:metabolism; D007700:Kinetics; D011392:Proline / Q000378:metabolism*; D013045:Species Specificity; D013386:Succinates / Q000378:metabolism
D000596:Amino Acids; D006601:Hexoses; D013386:Succinates; D011392:Proline