Comparison of ampicillin with clindamycin plus gentamicin in the treatment of postpartum uterine infection.
A prospective randomized study of the treatment of postpartum endometritis was conducted with 43 patients. The bacterial origin of the infection was determined by uterine aspiration. Treatment was successful in 17 of the 19 patients receiving ampicillin (12 g/d) and in 21 of the 24 patients receiving clindamycin (2.4 g/d) plus gentamicin (5.1 mg/kg daily).
D000667:Ampicillin / Q000627:therapeutic use*; D001431:Bacteriological Techniques; D002981:Clindamycin / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D004716:Endometritis / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage*; D006801:Humans; D011247:Pregnancy; D011446:Prospective Studies; D011645:Puerperal Infection / Q000188:drug therapy*; D011897:Random Allocation
D005839:Gentamicins; D002981:Clindamycin; D000667:Ampicillin