Changes in the metabolism of biogenic amines in alcoholism--especially regarding CSF monoamine metabolites and serum DBH activity.
Concentrations of the major metabolites of biogenic amines in cerebrospinal fluid and activity of serum dopamine-beta-hydroxylase in abstinent alcoholics were measured, suggesting that withdrawal symptoms of alcoholics were based on the abnormality of serotonin and dopamine metabolism in the body.
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000378:metabolism*; D001679:Biogenic Amines / Q000134:cerebrospinal fluid / Q000378:metabolism*; D004299:Dopamine beta-Hydroxylase / Q000097:blood*; D005260:Female; D006719:Homovanillic Acid / Q000134:cerebrospinal fluid; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid; D008297:Male; D008875:Middle Aged; D013375:Substance Withdrawal Syndrome / Q000378:metabolism; D013997:Time Factors
D001679:Biogenic Amines; D006897:Hydroxyindoleacetic Acid; D004299:Dopamine beta-Hydroxylase; D006719:Homovanillic Acid