[(Informed consent in clinical trials and its impact on methods of randomization and statistical evaluation)].
If patients eligible for a clinical trial are fully informed on alternative therapies, randomization, risks, benefits and right to refuse some of them will disagree with randomization. Random procedures which pay regard to that fact are described. The effect on statistical evaluation and sample sizes is investigated.
D002986:Clinical Trials as Topic; D006801:Humans; D007258:Informed Consent; D008962:Models, Theoretical; D011897:Random Allocation
Berücksichtigung der Aufklärungspflicht bei Therapiestudien und ihre Auswirkung auf Randomisierungs- und Auswertungsverfahren.