title: [Animal experiments on the detection of an exposure to "chemical mace" (author's transl)].
abstract: To answer the question whether a negative result of gas chromatographic blood analysis for components of chemical mace proves that no or at most only slight tear gas exposure can have occurred, animal experiments were carried out. In the blood of 10 guinea pigs, which were exposed to the contents of chemical mace for 1--6 h, the solvants 1,1,2-trichloro-1,2,2-trifluorethane (freon 113) and 1,1,1-trichloroethane could easily be detected--even 23 h after the end of exposure or after a storage of the blood samples for 18 weeks--whereas the lacrimator chloracetophenone (CN) could not be found at all. In vitro experiments showed that CN relatively quickly reacts with components of blood. Therefore, blood samples should be analyzed for CN after withdrawal as soon as possible. In case of inhalation of the contents of chemical mace, i.e., after the comparatively mildest form of CN application, most probably no traces of the lacrimator at all can pass into the blood due to the quick reaction of CN with proteins of the respiratory surface of the lung.
mesh_terms: D000818:Animals; D005617:Chlorofluorocarbons, Methane / Q000097:blood; D002849:Chromatography, Gas; D004781:Environmental Exposure; D006168:Guinea Pigs; D014240:Trichloroethanes / Q000097:blood; D002721:omega-Chloroacetophenone / Q000032:analysis*
chemical_list: D005617:Chlorofluorocarbons, Methane; D014240:Trichloroethanes; D002721:omega-Chloroacetophenone
vernacular_title: Tierexperimentelle Untersuchungen zum Nachweis einer Anwendung der "chemischen Keule".