Extramedullary plasmacytoma of the gastrointestinal tract in a renal transplant recipient.
A case of gastrointestional plasmacytoma found in a renal transplant recipient is described. Immunohistochemical study using immunoglobulin-enzyme bridge technique demonstrated IgA and k-type light chains in the majority of plasma cells infiltrated in the stomach. Pathological investigation revealed multiple similar tumors in the ileum, cecum and ascending colon suggesting a plasmacytoma of multicentric gastrointestinal origin. The pathogenesis of plasma cell tumors is briefly discussed with regard to organ transplantation.
D000328:Adult; D005770:Gastrointestinal Neoplasms / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007136:Immunoglobulins / Q000032:analysis; D007414:Intestinal Neoplasms / Q000473:pathology; D016030:Kidney Transplantation; D008297:Male; D010954:Plasmacytoma / Q000276:immunology / Q000473:pathology*; D011183:Postoperative Complications / Q000473:pathology*; D013274:Stomach Neoplasms / Q000473:pathology; D014184:Transplantation, Homologous
D007136:Immunoglobulins