An assay for histocompatibility gene mutations in mice.
A method used for detecting histocompatibility gene mutations by tailskin graft tests in mice is described. Advantages and disadvantages are found for this assay system. The results of published work point to some interesting features of the H-gene mutational event, but also leave many questions yet to be answered.
D000818:Animals; D005796:Genes; D005821:Genetic Techniques; D006649:Histocompatibility Antigens / Q000235:genetics*; D007158:Immunologic Techniques; D051379:Mice; D009154:Mutation; D016038:Skin Transplantation; D014181:Transplantation Immunology
D006649:Histocompatibility Antigens