Should the ruptured renal allograft be removed?
During a 16-month period when 93 renal transplants were performed, eight kidney graft ruptures were detected within 18 days of transplantation, without evidence of venous obstruction. Six grafts were removed at the time of an exploratory operation for rupture and only one showed signs of probable irreversible rejection when examined by microscopy. Two graft ruptures were repaired and one of these grafts has had good long-term function 22 months later. These observations suggest that if bleeding at the site of grafts has had good long-term function 22 months later. These observations suggest that if bleeding at the site of graft rupture can be securely controlled and if the conditions of the patient and of the graft are favorable except for the rupture, it may be possible to save more than one of eight grafts.
D000293:Adolescent; D000328:Adult; D002102:Cadaver; D006084:Graft Rejection; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007668:Kidney / Q000473:pathology / Q000601:surgery; D007674:Kidney Diseases / Q000601:surgery*; D016030:Kidney Transplantation; D008875:Middle Aged; D009392:Nephrectomy; D012422:Rupture, Spontaneous / Q000473:pathology / Q000601:surgery; D014184:Transplantation, Homologous
D007166:Immunosuppressive Agents