Management of surgical gastrointestinal complications in renal transplant recipients.
Gastrointestinal (GI) complications developed in 19 (7.2%) of 265 patients after renal transplantation, and 3 (16%) patients died. Complications included colon perforations, colonic bleeding, small-bowel infarction, pancreatitis, subphrenic abscess, and upper GI tract bleeding. Ulcers located in the second portion of the duodenum developed in six patients; four of them required operation for massive hemorrhage, which occurred during or immediately after the administration of high-dose methylprednisolone for rejection. However, the association of methylprednisolone and colon perforation was not clear from this report. Early diagnosis and prompt operation for surgical-type GI complications in transplant recipients contribute to a low mortality.
D000328:Adult; D003108:Colonic Diseases / Q000601:surgery; D005260:Female; D005767:Gastrointestinal Diseases / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D006471:Gastrointestinal Hemorrhage / Q000601:surgery; D006801:Humans; D007165:Immunosuppression Therapy; D007238:Infarction / Q000601:surgery; D007416:Intestinal Perforation / Q000601:surgery; D007421:Intestine, Small / Q000098:blood supply; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000601:surgery; D011183:Postoperative Complications / Q000401:mortality / Q000601:surgery*; D013369:Subphrenic Abscess / Q000601:surgery; D014184:Transplantation, Homologous