The bromination of 6-methyl-4-methoxy-2H-thiopyran-2-one.
The bromination of 6-methyl-4-methoxy-2H-thiopyran-2-one was studied under ionic and radical conditions. The 6-bromomethyl, respectively 6-dibromomethyl derivatives were hydrolyzed to the corresponding 6-hydroxymethyl and 6-formyl derivatives. The antibacterial and antimycotic activities of the new compounds were tested.
D000935:Antifungal Agents / Q000138:chemical synthesis; D001966:Bromine / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D006868:Hydrolysis; D008826:Microbial Sensitivity Tests; D011714:Pyrans / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects
D000935:Antifungal Agents; D011714:Pyrans; D001966:Bromine