title: Design of species- or isozyme-specific enzyme inhibitors. 2. Differences between a bacterial and a mammalian thymidine kinase in the effect of thymidine substituents on affinity for the thymidine site.
mesh_terms: D000818:Animals; D001665:Binding Sites; D006224:Cricetinae; D003593:Cytoplasm / Q000201:enzymology; D004926:Escherichia coli / Q000201:enzymology; D007700:Kinetics; D013045:Species Specificity; D013329:Structure-Activity Relationship; D013936:Thymidine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D013937:Thymidine Kinase / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D013937:Thymidine Kinase; D013936:Thymidine