[The clinical value of unspecific humoral immune parameters. Attempt at an immunogram. II. Quantitative determination of CH50E, CB50E, C3, C4 and lysozyme and measurement of indirect phagocytosis rate in the serum of patients with chronic pyelonephritis].
In 183 patients with chronic pyelonephritis as unspecific humoral immune parameters CH50E, CB50E, C3, C4 and lysozyme as well as the indirect phagocytosis against Staphylococcus aureus SG 511 and E. coli were tested. Clinically a differentiation according to 3 degrees of the renal function and 3 degrees of the activity of the disease was performed. The statistical analysis took into consideration mean and limit values. With the help of contingency tables tendency pictures were developed. C3, C4 and lysozyme proved as suitable for a humoral immunogramme in chronic pyelonephritis. C3 was increased in clear activity, C4 and lysozyme in restricted renal function and expressed activity. In view of the high biologic variation of humoral test parameters advantages and disadvantages of an immunogramme are discussed. But for patients with chronic pyelonephritis finally the estimations of IgM, IgG, IgD, C3, C4 and lysozyme are regarded as clinically useful. A feasable immunologic test set should be controlled, precised and completed.
D000328:Adult; D002908:Chronic Disease; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D003165:Complement System Proteins / Q000032:analysis*; D004926:Escherichia coli / Q000276:immunology; D006801:Humans; D009113:Muramidase / Q000032:analysis*; D010587:Phagocytosis; D011704:Pyelonephritis / Q000276:immunology*; D013211:Staphylococcus aureus / Q000276:immunology
D003176:Complement C3; D003181:Complement C4; D003165:Complement System Proteins; D009113:Muramidase
Untersuchungen zur klinischen Wertigkeit von unspezfischen humoralen Immunparametern. Versuch eines Immunogramms. II. Mitteilung. Die quantitative Bestimmung von CH50E, CB50E, C3, C4 und Lysozym sowie die Messung der indirekten Phagozytosebeeinflussung bei Seren von Patienten mit chronischer Pyelonephritis.