Identification of the ftsA gene product.
A nonsense mutation was identified in the essential cell division gene ftsA of Escherichia coli. A gamma-transducing phage was isolated which complemented this mutation. This phage programmed the synthesis of four bacterial proteins in UV-irradiated cells. By substituting the nonsense mutation for the ftsA+ allele in this transducing phage and comparing the proteins programmed by it in UV-treated Su+ and Su- cells, the product of the ftsA gene was identified as a protein with a molecular weight of 50,000.
D000483:Alleles; D001426:Bacterial Proteins / Q000032:analysis*; D002455:Cell Division; D003090:Coliphages / Q000235:genetics; D004926:Escherichia coli / Q000032:analysis* / Q000235:genetics / Q000528:radiation effects; D005796:Genes; D008970:Molecular Weight; D009154:Mutation; D014161:Transduction, Genetic; D014466:Ultraviolet Rays
D001426:Bacterial Proteins