[Chemotaxis of blood monocytes and polymorphonuclear leukocytes from patients with diabetes mellitus].
The chemotaxis of blood monocytes and polymorphonuclear leukocytes was measured in 20 adult patients with diabetes mellitus and 11 normal control subjects. In experiments dealing with monocytes, the diabetics had a chemotaxis value (125+/-10) significantly lower than that of controls (368+/-22); the polymorphonuclear leukocytes chemotaxis value of diabetics (468+/-31) was also lower than normal (1256+/-62). Adding insulin (10 unit/1000 cc) to the diabetes leukocytes suspension significantly increased the value of chemotaxis.
D000328:Adult; D000368:Aged; D002634:Chemotaxis, Leukocyte; D003920:Diabetes Mellitus / Q000276:immunology*; D005260:Female; D006801:Humans; D007328:Insulin / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000276:immunology; D009504:Neutrophils / Q000276:immunology
D007328:Insulin