Invasive pulmonary aspergillosis associated with influenza.
Fatal invasive pulmonary aspergillosis may follow viral influenza infections. Two cases with verified influenza A infection were followed by fatal necrotizing pneumonia due to Aspergillus fumigatus. Both patients demonstrated cutaneous anergy and lymphocytopenia. Influenza and perhaps other viruses that depress T-cell function may result in increased susceptibility to infections in which T cells are important in host defenses.
D000942:Antigens, Bacterial / Q000276:immunology; D001228:Aspergillosis / Q000209:etiology*; D001232:Aspergillus fumigatus; D001996:Bronchopneumonia / Q000209:etiology; D005260:Female; D006801:Humans; D009980:Influenza A virus / Q000276:immunology; D007251:Influenza, Human / Q000150:complications*; D008172:Lung Diseases, Fungal / Q000209:etiology*; D008231:Lymphopenia / Q000209:etiology; D008875:Middle Aged; D011024:Pneumonia, Viral / Q000209:etiology; D013601:T-Lymphocytes / Q000276:immunology
D000942:Antigens, Bacterial