Antimicrobial and cytolytic activity of N,N-dimethyl-l-methyldodecylamine oxide.
N,N-Dimethyl-l-methyldodecylamine oxide inhibited the growth of bacteria, yeast and filamentous fungi; further it induced lysis of osmotically stabilized protoplasts of Saccharomyces cerevisiae and human erythrocytes. This effect is based evidently on a change in the organization and function of cell membranes.
D000588:Amines / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D002462:Cell Membrane / Q000187:drug effects*; D004910:Erythrocyte Membrane / Q000187:drug effects; D005658:Fungi / Q000187:drug effects*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D009996:Osmotic Fragility / Q000187:drug effects; D010087:Oxides / Q000494:pharmacology; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000187:drug effects
D000588:Amines; D010087:Oxides