[A new method of anastomosing severed nerves].
Nerve anastomoses glued with "Fribrinkleber" can be protected from tissue plasminogen-activators both by natural and synthetic inhibitors of fibrinolysis whether administered locally or systemically. The glued nerve-anastomoses do not attain the bond strength of sutured nerves, but show less foreign body reaction. Gluing nerves with Fibrinkleber" combined with inhibition of fibrinolysis would seem to be a good method for reuniting severed nerves. It may be especially useful in nerve transplantation if tension is avoided.
D000818:Animals; D005169:Factor VIII / Q000494:pharmacology; D005337:Fibrin / Q000627:therapeutic use; D005340:Fibrinogen / Q000627:therapeutic use; D005549:Foreign-Body Reaction / Q000517:prevention & control; D059348:Peripheral Nerve Injuries; D010525:Peripheral Nerves / Q000601:surgery*; D051381:Rats; D012584:Sciatic Nerve / Q000187:drug effects / Q000601:surgery; D013917:Thrombin / Q000494:pharmacology; D013997:Time Factors; D014014:Tissue Adhesives / Q000009:adverse effects / Q000627:therapeutic use*
D014014:Tissue Adhesives; D005169:Factor VIII; D005337:Fibrin; D005340:Fibrinogen; D013917:Thrombin
Eine neue Methode der Anastomosierung durchtrennter peripherer Nerven.