In vitro enhancement of natural cytotoxicity by tumour necrosis serum.
Cells cytotoxic for syngeneic, allogeneic and xenogeneic cultured target cells are shown to be induced spontaneously in cultures of murine lymphoid cells. Serum containing bacillus Calmette-Guérin and endotoxin-induced tumour necrosis factor accelerates the appearance of observed natural cytotoxic cells.
D000818:Animals; D002478:Cells, Cultured; D004731:Endotoxins / Q000494:pharmacology; D005260:Female; D007106:Immune Sera; D007694:Killer Cells, Natural / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D009163:Mycobacterium bovis; D009336:Necrosis; D009368:Neoplasm Transplantation; D012513:Sarcoma, Experimental / Q000276:immunology* / Q000473:pathology / Q000628:therapy; D014185:Transplantation, Isogeneic
D004731:Endotoxins; D007106:Immune Sera