title: [Express method of detecting mutant forms of human serum cholinesterase].
abstract: An express method is developed for detection of patients carrying dibucaine-resistant and "silent" variants of cholinesterase in blood serum. 200 donors as well as 25 patients with various with various pathological syndroms were examined; 5 patients carrying dibucaine-resistant cholinesterase were detected, which constituted 2.22% in the group. The method might be used in anesthesiology, blood transfusion and in experimental studies of the problems of medical genetics.
mesh_terms: D002802:Cholinesterases / Q000097:blood* / Q000235:genetics; D002986:Clinical Trials as Topic; D003992:Dibucaine; D006580:Genetic Carrier Screening / Q000379:methods; D006720:Homozygote; D006801:Humans; D009154:Mutation; D013053:Spectrophotometry
chemical_list: D002802:Cholinesterases; D003992:Dibucaine
vernacular_title: Ekspress-metod vyiavleniia mutantnykh form kholinésterazy syvorotki krovi cheloveka.