Immunosuppressive effect of Trypanosoma congolense and Trypanosoma vivax on the secondary immune response of cattle to Mycoplasma mycoides subsp mycoides.
Trypanosoma congolense and T vivax infections in cattle were shown to have a suppressive effect on the secondary humoral immune response to M mycoides. The trypanosome infections caused an involution of the thymus. The secondary response was biphasic in nature and was unrelated to infection with trypanosomes.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000917:Antibody Formation; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D007108:Immune Tolerance; D009175:Mycoplasma Infections / Q000662:veterinary*; D009176:Mycoplasma mycoides / Q000276:immunology; D011002:Pleuropneumonia, Contagious / Q000276:immunology*; D014354:Trypanosomiasis, Bovine / Q000276:immunology*
D000907:Antibodies, Bacterial