X-14547A, a new ionophorous antibiotic produced by Streptomyces antibioticus NRRL 8167. Discovery, fermentation, biological properties and taxonomy of the producing culture.
X-14547A is a novel antibiotic produced by a new strain of Streptomyces antibioticus (NRRL 8167). The antibiotic is active in vitro against Gram-positive bacteria and is capable of complexing and transporting divalent as well as monovalent metal cations.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D000001:Calcimycin / Q000494:pharmacology; D005285:Fermentation; D007211:Indoles / Q000096:biosynthesis / Q000494:pharmacology; D007476:Ionophores / Q000096:biosynthesis / Q000494:pharmacology*; D007832:Lasalocid / Q000494:pharmacology; D013302:Streptomyces / Q000378:metabolism*; D013303:Streptomyces antibioticus / Q000145:classification / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D007211:Indoles; D007476:Ionophores; D000001:Calcimycin; D007832:Lasalocid