Mutagenic activity of Fusarium moniliforme isolates in the Salmonella typhimurium assay.
A total of 33 isolates of Fusarium moniliforme from several food or feed crops were grown on sterile cracked corn, and chloroform-isopropanol extracts were assayed for mutagenic activity in the Salmonella typhimurium-microsome system by using tester strain TA98 or TA100 or both. Extracts of 21 (64%) of the isolates assayed against TA100 were mutagenic. Activities of seven of these extracts were increased markedly with incorporation of the liver homogenate (S-9) into the assay. Seven (33%) of the isolates assayed against TA98 were weakly active, with the liver homogenate having little effect on reversion rates.
D000821:Animal Feed; D000818:Animals; D001681:Biological Assay / Q000379:methods*; D002523:Edible Grain / Q000382:microbiology; D005516:Food Microbiology; D005670:Fusarium / Q000032:analysis*; D008862:Microsomes, Liver / Q000187:drug effects; D009153:Mutagens / Q000032:analysis* / Q000494:pharmacology; D010935:Plant Diseases; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects*
D009153:Mutagens