Active T and EA-rosette-forming cells in human cadaver renal allograft recipients.
Active T(AT) and EA-rosette-forming cells (RFC) were determined in seventeen haemodialysis patients and twenty-two renal allograft recipients to correlate these estimates with the clinical outcome of renal allografts. Either AT- or EA-RFC or both were found to be elevated during the period of rejection crisis. Assays for AT- and EA-RFC were found to be complementary suggesting that they may be detecting two different types of rejection crises. Thus, determination of AT- and EA-RFC in the peripheral blood may prove to be useful in the routine immunological monitoring of renal allograft recipients.
D000328:Adult; D005260:Female; D006084:Graft Rejection; D006801:Humans; D016030:Kidney Transplantation; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*; D014181:Transplantation Immunology; D014184:Transplantation, Homologous