Early effects in kidney enzyme activities after irradiation.
Brush border enzymes of proximal tubules, lysosomal activities and protein content of rat kidney were analysed after whole-body irradiation using two different experimental schedules. Maltase, alkaline phosphatase and beta-glucuronidase activities increased moderately during the first days after irradiation, whereas LAP, cathespsin D activities and protein content were not modified. No evident morphologic alterations were observed.
D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D003037:Cobalt Radioisotopes; D005260:Female; D005966:Glucuronidase / Q000378:metabolism; D007668:Kidney / Q000528:radiation effects*; D007687:Kidney Tubules, Proximal / Q000201:enzymology / Q000473:pathology / Q000528:radiation effects*; D008247:Lysosomes / Q000201:enzymology / Q000528:radiation effects; D008871:Microvilli / Q000201:enzymology / Q000528:radiation effects; D011506:Proteins / Q000378:metabolism; D011829:Radiation Dosage; D051381:Rats; D013997:Time Factors; D000520:alpha-Glucosidases / Q000378:metabolism
D003037:Cobalt Radioisotopes; D011506:Proteins; D000469:Alkaline Phosphatase; D000520:alpha-Glucosidases; D005966:Glucuronidase