title: A portable, Preprogrammable insulin infusion system with 16 rates.
abstract: An external, portable, programmable pump has been developed for long-term therapeutic i.v. insusion of drugs. The impulse-controlled system consists of a 250 g CMOS-electronic unit and an electromechanical infusor (200 g) containing a 10 ml disposable syringe. The infusion pattern during the 24-h cycle is manually programmed in 16 steps from 24 to 384 microliter per 0.5 h. The coefficient of variation of the infusate is less than 2% per 0.5 h. An alarm circuit monitors the pump speed and the reservoir volume. The infusion system can operate continuously for 7 days with a 1 Ah, 5.4 volt battery.
mesh_terms: D001187:Artificial Organs; D003920:Diabetes Mellitus / Q000188:drug therapy*; D005246:Feedback; D006801:Humans; D007263:Infusions, Parenteral / Q000295:instrumentation*; D007328:Insulin / Q000008:administration & dosage* / Q000627:therapeutic use; D007515:Islets of Langerhans / Q000378:metabolism
chemical_list: D007328:Insulin