Molecular characteristic of antibodies in the blood serum and in the lymph nodes during fractional immunization with small doses of bacterial vaccines.
An experiment on 58 rabbits demonstrated that only macromolecular agglutinins 19S are present in extracts from the lymph nodes after fractional immunization with small doses of typhoid vaccine or some dysentery vaccine. At the same time, antibodies in the blood serum are distributed in fractions of different molecular weight, starting from the 14th day of experiment. It is very probable that this distribution of antibodies is associated with the occurrence in the blood of an inhibitor of the activity of macromolecular antibodies.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis*; D001428:Bacterial Vaccines / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology*; D008970:Molecular Weight; D011817:Rabbits; D012764:Shigella sonnei / Q000276:immunology; D013997:Time Factors; D014436:Typhoid-Paratyphoid Vaccines / Q000276:immunology
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D014436:Typhoid-Paratyphoid Vaccines