[Preparation and evaluation of antibacterial activity of partial fractions of Vallesia antillana Wood].
A study on the antibacterial properties of alkaloidal fractions of Vallesia antillana Wood, a Cuban plant belonging to the Apocynaceae family, is performed for the first time. Four partial fractions from bark of stems were prepared according to a classical extraction of total alkaloids and a partial fractionation of these, with the use of tartaric acid and ethyl ether and by a pH gradient with values of 2.5, 5.0, 7.0 and alkaline one. Data from thin layer chromatography on the alkaloidal content of different fractions are added and an assessment of antibacterial activity was made; for this, a method of sections in agar medium with bacterial species of human clinical interest was used; inhibitory halos found within 24 hours of incubation at 37 degrees C are reported in millimeters.
D000470:Alkaloids / Q000032:analysis* / Q000494:pharmacology; D000900:Anti-Bacterial Agents; D001419:Bacteria / Q000187:drug effects; D002855:Chromatography, Thin Layer / Q000379:methods*; D004341:Drug Evaluation; D010936:Plant Extracts / Q000032:analysis*; D010947:Plants, Toxic / Q000032:analysis*
D000470:Alkaloids; D000900:Anti-Bacterial Agents; D010936:Plant Extracts
Preparación y evaluación de la actividad antibacteriana de fracciones parciales de Vallesia antillana Wood.