Activation of T-cells by a macrophage or 2-mercaptoethanol activated serum factor is essential for induction of a primary immune response to heterologous red cells in vitro.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D001402:B-Lymphocytes / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D006131:Growth Inhibitors / Q000494:pharmacology; D066298:In Vitro Techniques; D007939:Leukemia L1210 / Q000188:drug therapy; D008213:Lymphocyte Activation / Q000187:drug effects; D008223:Lymphoma / Q000188:drug therapy; D008264:Macrophages / Q000276:immunology*; D008623:Mercaptoethanol / Q000494:pharmacology*; D051379:Mice; D008815:Mice, Inbred Strains; D013601:T-Lymphocytes / Q000276:immunology*
D006131:Growth Inhibitors; D008623:Mercaptoethanol