title: Physical and biological aspects of fracture healing with special reference to internal fixation.
abstract: Fracture healing is a repair process of a mechanical discontinuity loss of force transmission, and pathological mobility of bone. Through a sequence of changes of tissue development and geometry, the original structural integrity is restored. The recovery of rigidity and strength is related to tissue differentiation. In unified theory of non-operative and operative stabilized fractures, the mechanics of primary bone healing involves a complex interplay of physical and biological factors. The different patterns of bone repair respond to physical influences including strain tolerance.
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001860:Bone Plates; D001862:Bone Resorption; D001863:Bone Screws; D001842:Bone and Bones / Q000503:physiopathology; D002146:Bony Callus; D005593:Fracture Fixation, Internal; D005594:Fracture Fixation, Intramedullary; D050723:Fractures, Bone / Q000503:physiopathology / Q000601:surgery*; D006253:Haversian System / Q000503:physiopathology; D006801:Humans; D009336:Necrosis; D011312:Pressure; D013203:Staphylococcal Infections / Q000150:complications; D013314:Stress, Mechanical; D014945:Wound Healing