[Plasma cell beta-glucuronidase and monoclonal gammapathies (author's transl)].
beta-glucuronidase activity, estimated cytochemically, is, in more than half cases of myeloma, very increased or decreased, compared to that found in benign dysglobulinemias, where this activity is normal. A very high or very low score makes sure the diagnostic of myeloma. The relations between the beta-glucuronidase activity and the myeloma clinical stade according to Durie and Salmon and the bone lysis are discussed.
D004796:Clinical Enzyme Tests; D003937:Diagnosis, Differential; D005966:Glucuronidase / Q000378:metabolism*; D006801:Humans; D006942:Hypergammaglobulinemia / Q000175:diagnosis*; D009101:Multiple Myeloma / Q000175:diagnosis / Q000201:enzymology; D010950:Plasma Cells / Q000201:enzymology*
D005966:Glucuronidase
beta-Glucuronidases plasmocytaires dans les dysglobulinémies. Intérêt diagnostique de leur mise en évidence.