On the intracerebral locus for androgenization of female rats.
Comparison of control and androgenized rats has revealed that many nerve terminals ending on arcuate nerve cells of rats treated neonatally with testosterone phenylpropionate show a decrease in dense-core vesicles, and an increase in the number of clear vesicles and of vesicles that exhibit various degrees of electron density. The same changes were observed in nerve terminals ending on preoptic neurons of rats androgenized neonatally. These findings are discussed in view of the intracerebral locus for androgenization of female rats.
D000818:Animals; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000096:biosynthesis; D007031:Hypothalamus / Q000187:drug effects*; D009411:Nerve Endings / Q000648:ultrastructure; D009474:Neurons / Q000187:drug effects; D009940:Organoids / Q000187:drug effects; D011301:Preoptic Area / Q000187:drug effects* / Q000648:ultrastructure; D051381:Rats; D013739:Testosterone / Q000494:pharmacology*
D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone