Trimethoprim resistance plasmids of different origin encode different drug-resistant dihydrofolate reductases.
D002729:Chloromercuribenzoates / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D010957:Plasmids / Q000187:drug effects*; D013045:Species Specificity; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics*; D014295:Trimethoprim / Q000494:pharmacology*
D002729:Chloromercuribenzoates; D014295:Trimethoprim; D013762:Tetrahydrofolate Dehydrogenase