Creutzfeldt-Jakob disease and optic atrophy.
A 49-year-old man developed ataxia, myoclonic jerks, cortical blindness, and dementia. In 3 1/2 months, he rapidly deteriorated and died. Clinical and autopsy diagnosis confirmed Creutzfeldt-Jakob disease. The eyes were examined and bilateral optic atrophy was noted. No other ocular changes were noted. Optic atrophy had not been noted before death.
D003315:Cornea / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000150:complications* / Q000473:pathology; D003711:Demyelinating Diseases / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009778:Occipital Lobe / Q000473:pathology; D009896:Optic Atrophy / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D009900:Optic Nerve / Q000473:pathology; D012160:Retina / Q000473:pathology; D014794:Visual Fields