[Transitional tumours of urinary bladder (author's transl)].
An overall survey of the transitional epithelium of the bladder and its carcinomas. This study is based upon the recent literature, in particular the considerable contribution of scanner electron microscopy. a) The transitional epithelium has the reputation of having a simple structure and even behaviour. In fact, it is complex with highly specialised surface cells. It has marked powers of regeneration after aggressions of various types. b) Tumours of the transitional epithelium are defined in relation to rupture of the basal lamina. Invasive carcinomas are classified according to their histological stage of penetration, their pure or partially metaplasic type and their degree defined according to the criteria of Broders. There exists a correlation between these three types of evaluation. Non-invasive carcinomas are either papillary--putting into question the reality of benign bladder papilloma--or flat mucosal and then often associated closely or at a distance with an invasive carcinoma. c) Abnormal regeneration, dysplasia or hyperplasia as a result of aggressions of different types or developing in isolation represent a high risk histologically, implying the need for careful follow-up and surveillance. d) Histopathological study of urothelial or transitional tumours is simple in operative specimens but difficult in biopsies. It requires close cooperation between surgeons and pathologists to ensure correct orientation of the fragments.
D002278:Carcinoma in Situ / Q000648:ultrastructure; D002291:Carcinoma, Papillary / Q000648:ultrastructure; D002295:Carcinoma, Transitional Cell / Q000145:classification / Q000648:ultrastructure*; D004848:Epithelium / Q000648:ultrastructure; D006801:Humans; D006965:Hyperplasia; D008679:Metaplasia; D008854:Microscopy, Electron; D011230:Precancerous Conditions; D001749:Urinary Bladder Neoplasms / Q000648:ultrastructure*
La pathologie des carcinomes vésicaux. Evolution des idées.