Evaluation and comparison of two assays for detection of immunity to rubella infection.
Two commercially available rapid screening tests, Rubacell (Abbott Laboratories; passive hemagglutination) and FIAX (International Diagnostic Technology; indirect immunofluorescence) were compared with a standard hemagglutination inhibition assay for detection of immunity to rubella infection. In tests of approximately 300 sera, both rapid assays were specific and sensitive and showed a high predictive value of a positive result. Within-run reproducibility studies were excellent for both tests; however, Rubacell was superior to FIAX with respect to time-cost analysis.
D000914:Antibodies, Viral / Q000032:analysis; D005455:Fluorescent Antibody Technique / Q000191:economics; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests / Q000191:economics / Q000379:methods*; D006801:Humans; D012409:Rubella / Q000276:immunology*
D000914:Antibodies, Viral