[Pharmacology of fibrinolytics].
The pharmacological basis for clinical uses of the fibrinolytic agents streptokinase and urokinase is summarizing described. Since streptokinase is still the drug of choice in fibrinolytic therapy of thromboembolic disorders, its chemistry, mode of action, pharmacokinetics, toxicity, and side-effects are reported in detail.
D010450:Endopeptidases / Q000494:pharmacology*; D005343:Fibrinolytic Agents / Q000009:adverse effects / Q000494:pharmacology* / Q000633:toxicity; D006801:Humans; D013300:Streptokinase / Q000009:adverse effects / Q000494:pharmacology* / Q000633:toxicity; D014568:Urokinase-Type Plasminogen Activator / Q000494:pharmacology*
D005343:Fibrinolytic Agents; D010450:Endopeptidases; D013300:Streptokinase; D014568:Urokinase-Type Plasminogen Activator
Zur Pharmakologie der Fibrinolytika.