Double-blind, crossover comparison of carbuterol and salbutamol.
The bronchodilator efficacy of oral carbuterol in the dose of 2 mg or 3 mg was compared with that of 4 mg salbutamol in a double-blind, crossover trial in 21 patients with bronchial asthma. Carbuterol 3 mg was found to be a more effective bronchodilator than salbutamol 4 mg. Both the drugs in these doses produced mild tachycardia but were otherwise well tolerated.
D000293:Adolescent; D000328:Adult; D000420:Albuterol / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy; D001794:Blood Pressure / Q000187:drug effects; D001993:Bronchodilator Agents / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004983:Ethanolamines / Q000627:therapeutic use*; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008450:Maximal Midexpiratory Flow Rate; D008875:Middle Aged; D011674:Pulse / Q000187:drug effects; D012129:Respiratory Function Tests
D001993:Bronchodilator Agents; D004983:Ethanolamines; D000420:Albuterol