[Determination of auto-antibodies against spermatozoa after vasectomy and epididymectomy by indirect immunofluorescence (author's transl)].
As a result of successful recanalization of the vas deferens, a low pregnancy rate has been observed. The formation of auto-antibodies is considered as cause. In vasectomized and epididymectomized rats, the presence of auto-antibodies against spermatozoa was proven by indirect immunofluorescence. After uni- and/or bilateral obstruction of the vasa, the formation of antibodies against spermatozoa takes place which - after 2 months - proves to be permanent for 9 months, then showing a decreased titre. An animal model is presented suitable for the study of immunological processes in unilateral gonadal diseases.
D000818:Animals; D001323:Autoantibodies / Q000032:analysis*; D004822:Epididymis / Q000601:surgery*; D005455:Fluorescent Antibody Technique; D008297:Male; D051381:Rats; D013094:Spermatozoa / Q000276:immunology*; D014659:Vasectomy
D001323:Autoantibodies
Nachweis von zirkulierenden Spermatozoen-Antikörpern nach Vasektomie und Epididymektomie mittels der Technik fluoreszierender Antikörper.