Nuclear inheritance of resistance to antimycin A in Saccharomyces cerevisiae.
A group of 30 independent mutants of Saccharomyces cerevisiae, resistant to the respiratory inhibitor antimycin A, was investigated from a genetical and biochemical point of view. All the mutants can be grouped into two nuclear loci: AMY1 maps on the VII chromosome, between leu 1 and trp 5; AMY2 is close to its centromere on either chromosome XVIII or XIX. Both genes do not affect mitochondrial structures or functions.
D000968:Antimycin A / Q000494:pharmacology*; D002467:Cell Nucleus / Q000648:ultrastructure; D002874:Chromosome Mapping; D004352:Drug Resistance, Microbial; D005796:Genes; D008928:Mitochondria / Q000648:ultrastructure; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics*
D000968:Antimycin A