A comparison of the antibacterial activity of sulphonamide-trimethoprim combinations.
Sensitivity patterns of 326 clinical isolates toward sulphonamide/trimethoprim combinations were tested in vitro. The relative merits of the different combinations are discussed in their pharmacological and bacteriological contexts. It is concluded that organisms sensitive to cotrimoxazole as judged by in vitro sensitivity tests performed at 37 degrees C are also sensitive to sulphamoxole/trimethoprim.
D004338:Drug Combinations; D004926:Escherichia coli / Q000187:drug effects; D007711:Klebsiella pneumoniae / Q000187:drug effects; D008826:Microbial Sensitivity Tests / Q000379:methods; D011513:Proteus mirabilis / Q000187:drug effects; D011514:Proteus vulgaris / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013420:Sulfamethoxazole / Q000494:pharmacology*; D013423:Sulfamoxole / Q000494:pharmacology*; D014295:Trimethoprim / Q000494:pharmacology*
D004338:Drug Combinations; D014295:Trimethoprim; D013423:Sulfamoxole; D013420:Sulfamethoxazole