Aldactone and acebutolol in treatment of hypertension.
Twenty-one essential hypertensives were randomly treated with Aldactone, acebutolol or a combination of the two drugs. Statistically significant falls in systolic and diastolic pressures were demonstrated during treatment with Aldactone 100 mg daily, also when acebutolol and Aldactone 200 mg daily were administered. When the combination of Aldactone and acebutolol was given, diastolic pressures were lowered to a greater degree than seen with individual treatments.
D000070:Acebutolol / Q000627:therapeutic use*; D000328:Adult; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010919:Placebos; D013148:Spironolactone / Q000627:therapeutic use*
D010919:Placebos; D013148:Spironolactone; D000070:Acebutolol