title: Mutagenicity tests of diflubenzuron in the micronucleus test in mice, the L5178Y mouse lymphoma forward mutation assay, and the Ames Salmonella reverse mutation test.
abstract: Diflubenzuron, one of a new class of pesticides believed to act via inhibition of chitin synthesis in the developing insect cuticle, was tested for possible mutagenic activity using the micronucleus test in mice, the L5178Y mouse lymphoma forward mutation test at the thymidine kinase locus, and the Ames Salmonella/microsome reverse mutation test. No mutagenic effect was found.
mesh_terms: D000818:Animals; D002460:Cell Line; D004132:Diflubenzuron / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical; D005821:Genetic Techniques; D007605:Juvenile Hormones / Q000494:pharmacology*; D051379:Mice; D009153:Mutagens; D009154:Mutation; D051381:Rats; D012486:Salmonella typhimurium / Q000235:genetics
chemical_list: D007605:Juvenile Hormones; D009153:Mutagens; D004132:Diflubenzuron