title: Intra-nasal flunisolide in the treatment of allergic rhinitis in general practice.
abstract: An open trial was carried out in general practice to assess the effectiveness and acceptability of flunisolide nasal spray in relieving symptoms of allergic rhinitis. Eighty-eight patients were entered in the study, 82 of whom were hay fever sufferers. The spray was given as 2 insufflations into each nostril, using a metered pump, twice daily over a period of 1 month. This provided a daily dose of 200 microgram flunisolide. Patients' symptoms were assessed on entry and at 2-week intervals. Flunisolide produced statistically significant reductions in all symptoms and resulted in complete or good control in 73 patients.
mesh_terms: D000281:Administration, Intranasal; D000293:Adolescent; D000328:Adult; D000336:Aerosols; D000368:Aged; D002648:Child; D002986:Clinical Trials as Topic; D005194:Family Practice; D005260:Female; D005446:Fluocinolone Acetonide / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011058:Pollen; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy*; D013997:Time Factors
chemical_list: D000336:Aerosols; D005446:Fluocinolone Acetonide