[Evaluation of the effectiveness of ALG in clinical kidney transplantation in alternating studies].
The efficacy of ALG (horse serum against cultured human lymphocytes) in addition to a standard azathioprine and steroid regimen has been investigated in an alternating series of 70 renal transplantations in adults. Patient survival was almost identical in both groups. Transplant survival after 2 years was 64% in the ALG group as opposed to 48% in the group without ALG. In agreement with current literature, immunosuppression with ALG in high dosage seems to be justified.
D000328:Adult; D000961:Antilymphocyte Serum / Q000627:therapeutic use*; D001379:Azathioprine / Q000627:therapeutic use*; D002648:Child; D005069:Evaluation Studies as Topic; D005260:Female; D006084:Graft Rejection; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use*; D014184:Transplantation, Homologous
D000961:Antilymphocyte Serum; D011239:Prednisolone; D001379:Azathioprine
Effektivitätsbeurteilung von ALG bei klinischer Nierentransplantation in alternierender Studie.