title: High-dose methotrexate therapy--an area of uncertainty.
mesh_terms: D006801:Humans; D007700:Kinetics; D002955:Leucovorin / Q000008:administration & dosage; D008727:Methotrexate / Q000008:administration & dosage* / Q000009:adverse effects / Q000378:metabolism / Q000494:pharmacology; D009369:Neoplasms / Q000188:drug therapy; D011485:Protein Binding
chemical_list: D002955:Leucovorin; D008727:Methotrexate