A double-blind crossover trial of baclofen--a new treatment for the unstable bladder syndrome.
Forty patients with the unstable bladder syndrome have been treated in a double-blind crossover trial of baclofen 5 mg qds versus placebo. Baclofen significantly improved diurnal and nocturnal frequency of micturition and the severity of incontinence. Considerable improvement was also obtained with placebo.
D001418:Baclofen / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D001745:Urinary Bladder Diseases / Q000188:drug therapy*; D014549:Urinary Incontinence / Q000188:drug therapy*; D014555:Urination Disorders / Q000188:drug therapy
D001418:Baclofen