Prevalence of antibodies to Toxoplasma gondii in pregnant women in Oregon.
Sera from 95,929 pregnant women were screened for antibodies to Toxoplasma gondii with the indirect hemagglutination test (IHA) at a 1:64 dilution of the sera. An indirect fluorescent antibody-IgM specific test (IFA-IgM) was used on all sera found to have an IHA titer of greater than or equal to 1:256. From August 1973 to December 1976, 8.1% of pregnant women had IHA titers of greater than or equal to 1:64. In addition, 129 (18.4%) of 700 pregnant women with IHA titers of greater than or equal to 1:256 had IFA-IgM titers of greater than or equal to 1:4. The IHA test was an acceptable test for mass screening of sera from pregnant women. In Oregon, one in every 200 women contracts toxoplasmosis during her pregnancy.
D000293:Adolescent; D000328:Adult; D000375:Aging; D000906:Antibodies; D005260:Female; D005455:Fluorescent Antibody Technique; D006386:Hemagglutination Tests; D006801:Humans; D007075:Immunoglobulin M; D009922:Oregon; D011247:Pregnancy; D013997:Time Factors; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000175:diagnosis*; D014125:Toxoplasmosis, Congenital / Q000209:etiology
D000906:Antibodies; D007075:Immunoglobulin M