title: [Very extensive ulcers in a case of mixed cryoglobulinemia].
abstract: A young girl suffering from mixed cryoglobulinemia had shown since puberty ulcers of the lower limbs. A first very serious occurrence of necrotic lesions of the feet was stopped through the use of bilateral lumbar sympathectomy and grafts. A second extremely serious onset was cured using peridural lumbar anesthesia maintained for six weeks. D-penicillamine proved inefficient.
mesh_terms: D000293:Adolescent; D000328:Adult; D000767:Anesthesia, Epidural; D003450:Cryoglobulins / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007871:Leg Ulcer / Q000209:etiology* / Q000628:therapy; D010265:Paraproteinemias / Q000150:complications*; D016038:Skin Transplantation; D013562:Sympathectomy; D014182:Transplantation, Autologous
chemical_list: D003450:Cryoglobulins; D007070:Immunoglobulin A; D007075:Immunoglobulin M
vernacular_title: Ulcères très étendus dans un cas de cryoglobulinémie mixte.