Intra-nasal flunisolide in the treatment of allergic rhinitis in general practice.
An open trial was carried out in general practice to assess the effectiveness and acceptability of flunisolide nasal spray in relieving symptoms of allergic rhinitis. Eighty-eight patients were entered in the study, 82 of whom were hay fever sufferers. The spray was given as 2 insufflations into each nostril, using a metered pump, twice daily over a period of 1 month. This provided a daily dose of 200 microgram flunisolide. Patients' symptoms were assessed on entry and at 2-week intervals. Flunisolide produced statistically significant reductions in all symptoms and resulted in complete or good control in 73 patients.
D000281:Administration, Intranasal; D000293:Adolescent; D000328:Adult; D000336:Aerosols; D000368:Aged; D002648:Child; D002986:Clinical Trials as Topic; D005194:Family Practice; D005260:Female; D005446:Fluocinolone Acetonide / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011058:Pollen; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy*; D013997:Time Factors
D000336:Aerosols; D005446:Fluocinolone Acetonide