Adenocarcinoma of the pancreas associated with hypoglycemia: case report and review of the literature.
The occurrence of profound hypoglycemia in a patient with metastatic adenocarcinoma of the pancreas is reported. In contrast to the four previously reported cases, no suggestion of excess insulin production was found. Metabolic studies in this patient suggest both increased peripheral glucose utilization and decreased hepatic glucose production as contributing factors which promoted the hypoglycemia.
D000230:Adenocarcinoma / Q000150:complications* / Q000378:metabolism; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000150:complications* / Q000378:metabolism; D007328:Insulin / Q000096:biosynthesis; D007773:Lactates / Q000097:blood; D008099:Liver / Q000378:metabolism; D009362:Neoplasm Metastasis; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000378:metabolism
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D007773:Lactates