title: Status asthmaticus in children: a one-year study.
abstract: 50 children were admitted on 72 occasions during one year in status asthmaticus, defined as wheezing not relieved by two doses of bronchodilator 4 hours apart. At least one-third of children were hypercapnoeic on admission. They were managed with either oral prednisolone and nebulised salbutamol. Those with peak expiratory flow rates of greater than 25% expected for height were satisfactorily managed on the oral regimen. One child needed assisted ventilation. 73% were fit for discharge within 4 days and more than half of them needed a change in maintanance treatment.
mesh_terms: D000293:Adolescent; D000420:Albuterol / Q000627:therapeutic use; D000628:Aminophylline / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy* / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007223:Infant; D007385:Intermittent Positive-Pressure Ventilation; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D000628:Aminophylline; D011239:Prednisolone; D000420:Albuterol; D006854:Hydrocortisone