title: [The anatomical and histological investigation of the pancreas in the 19th century and till the discovery of insulin (1921). 4. The pancreas-research after the discovery of pancreas-diabetes (1889) till the discovery of insulin].
abstract: In this study is the history of the pancreas-research between 1889 and 1921 described. In this period are any important discoverys detected: The islets have 2 cell types (TSCHASSOW-NIKOW 1900, 1906); the connection between diabetes mellitus and islet-alterations (OPIE 1900); the independence of islets on exocrine parenchyma (SCHULZE 1900); the discovery of internal secretion (BAYLISS, STARLING 1902) and the regeneration of islets in mammals and the man (KYRLE 1908; WEICHSELBAUM 1908 in independent publications.
mesh_terms: D003920:Diabetes Mellitus / Q000266:history*; D005060:Europe; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D007328:Insulin / Q000266:history*; D007515:Islets of Langerhans / Q000033:anatomy & histology; D010179:Pancreas / Q000033:anatomy & histology / Q000378:metabolism; D012106:Research
chemical_list: D007328:Insulin
vernacular_title: Die anatomisch-histologische Erforschung des Pankreas vom Beginn des 19. Jahrhunderts bis zur Entdeckung des Insulins durch BANTING und BEST (1921) unter Berücksichtigung physiologischer Aspekte. 4. Die Pankreasforschung nach der Entdeckung des Pankreas-Diabetes (1889) bis zur Entdeckung des Insulins.