A familial occurrence of allergic bronchopulmonary aspergillosis.
A family was recently studied in which two brothers with identical HLA serotypes had allergic bronchopulmonary aspergillosis. One of the two had a normal bronchogram. A field investigation of the family residence showed that a barn was the probable source of the organism causing disease in these patients. Immunologic characterization of the family members showed a broad spectrum of response to the environmental exposure.
D000293:Adolescent; D000328:Adult; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000000981:diagnostic imaging / Q000235:genetics* / Q000276:immunology; D001249:Asthma / Q000150:complications; D001995:Bronchography; D002648:Child; D002675:Child, Preschool; D003231:Conjunctivitis / Q000150:complications; D004197:Disease Reservoirs; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D007158:Immunologic Techniques; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D012220:Rhinitis / Q000150:complications; D012882:Skin Tests
D006680:HLA Antigens