title: Orgotein in equine navicular disease: a double blind study.
abstract: Fourteen horses (7 treated with orgotein and 7 treated with a placebo) with navicular disease were studied on a double blind basis. All 14 horses had clinical and radiographic evidence of navicular disease. Orgotein and the placebo were administered by juxtabursal injection. Of the 7 orgotein-treated horses, 3 responded but none of the 7 placebo-treated horses responded. The difference was statistically significant (P less than 0.05).
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002062:Bursitis / Q000188:drug therapy / Q000662:veterinary; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005534:Foot Diseases / Q000188:drug therapy / Q000662:veterinary*; D005552:Forelimb; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D007273:Injections, Intramuscular; D008297:Male; D008667:Metalloproteins / Q000008:administration & dosage / Q000627:therapeutic use*; D010000:Osteitis / Q000662:veterinary*
chemical_list: D000893:Anti-Inflammatory Agents; D008667:Metalloproteins; C005180:orgotein