Can a small blood vessel prosthesis be derived from heterologous foreign body reactive tissue?
This study investigated as a small diameter vascular replacement the tissue formed adjacent to an implanted cylindrical foreign body, heterologously transplanted. Grafts of 4 mm i.d. were grown in rabbits and transplanted to dogs as segmental carotid and femoral artery replacements. These maintained 50% patency after 3 weeks. Variables in the further development of this concept are discussed.
D000818:Animals; D001705:Bioprosthesis; D001807:Blood Vessel Prosthesis; D003094:Collagen; D003238:Connective Tissue / Q000473:pathology; D004285:Dogs; D005260:Female; D005549:Foreign-Body Reaction / Q000473:pathology*; D008297:Male; D011474:Prosthesis Design; D011817:Rabbits; D012826:Silicone Elastomers
D012826:Silicone Elastomers; D003094:Collagen