title: Histiocytic lymphoma in a patient with Lennert's lymphoma. Report of a case with unusual cytoplasmic inclusions.
abstract: The transformation of Lennert's lymphoma into histiocytic lymphoma appears to be part of the natural history of the disorder rather than therapeutically induced. Unusual paranuclear nonmembrane-bound filamentous inclusions were found in many of the neoplastic cells in the histiocytic lymphoma. We report evidence for the immunoglobulin nature of this material, indicating a B cell origin of the neoplasm.
mesh_terms: D000008:Abdominal Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007120:Immunochemistry; D008198:Lymph Nodes / Q000473:pathology; D008223:Lymphoma / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology* / Q000648:ultrastructure; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary