title: [Carpipramine in psychoses].
abstract: A survey of 131 psychotic subjects treated with carpipramine and a synthesis of the Japanese, German and French publications about this drug were done. The most valuable results were obtained in hebephrenics and in depressed schizophrenics. Carpipramine has a definite desinhibitory action against motor retardation, lack of energy, ideo-motor slowliness and blunting of the affect. At low doses, paranoid schizophrenics become worse. The emerged delusional and anxious phenomena, can be avoided by using higher doses. This drug possesses two kinds of effects: antidelusional and desinhibitory actions. If it does not seem to be a true antidepressant, Carpipramine proves useful in deficits of the psychomotor tone, which were resistant to antidepressant drugs.
mesh_terms: D001714:Bipolar Disorder / Q000188:drug therapy; D002986:Clinical Trials as Topic; D003984:Dibenzazepines / Q000627:therapeutic use*; D006801:Humans; D007266:Inhibition, Psychological; D010259:Paranoid Disorders / Q000188:drug therapy; D011618:Psychotic Disorders / Q000188:drug therapy*; D012562:Schizophrenia, Disorganized / Q000188:drug therapy
chemical_list: D003984:Dibenzazepines
vernacular_title: La carpipramine au cours des psychoses.