Multifocal adenocarcinoma of the jejunum.
We report on an 89-year-old female admitted with signs of intestinal obstruction in whom three independent adenocarcinomas of the proximal jejunum were found. Multiple foci of pyloric gland metaplasia, glandular hyperplasia and dysplasia, carcinoma-in-situ, and several varieties of adenocarcinoma were identified on microscopic examination of 14 cm of excised jejunum. Multifocal adenocarcinoma of the small intestine is extremely rare. We are not aware of any case harboring the complex changes described herein.
D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D002278:Carcinoma in Situ / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007580:Jejunal Neoplasms / Q000473:pathology*; D008679:Metaplasia; D009378:Neoplasms, Multiple Primary / Q000473:pathology*