title: Blood glucose monitoring and computer regulation by means of an artificial endocrine pancreas.
abstract: Extracorporeal blood glucose regulation has been implemented by a closed-loop system (artificial endocrine pancreas, "aep") of our own construct. Simple, highly flexible algorithms have been developed that allow smooth repair of a deranged glucose imbalance up to a period of 125 hours.
mesh_terms: D001187:Artificial Organs; D001786:Blood Glucose / Q000032:analysis*; D003201:Computers; D003920:Diabetes Mellitus / Q000188:drug therapy*; D005246:Feedback; D006801:Humans; D007263:Infusions, Parenteral; D007328:Insulin / Q000008:administration & dosage* / Q000627:therapeutic use; D007515:Islets of Langerhans / Q000378:metabolism*; D008433:Mathematics; D008875:Middle Aged; D008991:Monitoring, Physiologic
chemical_list: D001786:Blood Glucose; D007328:Insulin