title: Effect of a serine protease on isolated myofibrils.
abstract: Morphological changes occurred in myofibrils prepared from the glycerinated psoas muscle of rabbit during incubation with a serine protease crystallized from rat skeletal muscle. Two notable phenomena were observed: (1) loss of the Z band in the early stage of incubation and (2) complete disappearance of the A band after swelling of the myofibrils. The results indicate that the serine protease has an action on myofibrils different from that of Ca2+-dependent neutral protease.
mesh_terms: D000818:Animals; D010450:Endopeptidases / Q000378:metabolism*; D008858:Microscopy, Phase-Contrast; D008970:Molecular Weight; D009132:Muscles / Q000201:enzymology; D009210:Myofibrils / Q000648:ultrastructure*; D051381:Rats; D012694:Serine
chemical_list: D012694:Serine; D010450:Endopeptidases