title: Normocapnic anaesthesia with trichloroethylene for intraocular surgery.
abstract: Measurements of intraocular pressure (IOP) by applanation tonometry in twelve patients undergoing lens extraction showed that a normocapnic anaesthetic technique using 0.4% trichloroethylene with controlled ventilation of the lungs (IPPV) with large tidal volumes (14 ml/kg) reduced IOP by 13--20%. There was only a small reduction in arterial pressure. Normocapnia was easy to achieve by use of the single-limb co-axial Penlon (Bain type) anaesthetic breathing circuit in conjunction with an electrically-driven, small and inexpensive lung ventilator. The anaesthetic technique described using trichloroethylene is suitable for lens extraction surgery when it is desired to avoid a halothane anaesthetic for any reason.
mesh_terms: D000368:Aged; D000769:Anesthesia, Inhalation; D001794:Blood Pressure / Q000187:drug effects; D002245:Carbon Dioxide / Q000097:blood*; D002387:Cataract Extraction; D005260:Female; D006221:Halothane; D006801:Humans; D007385:Intermittent Positive-Pressure Ventilation; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D014241:Trichloroethylene / Q000494:pharmacology
chemical_list: D002245:Carbon Dioxide; D014241:Trichloroethylene; D006221:Halothane