[Removal of human kidneys under "in situ" hypothermia by aortic and caval cannulations. Technique and first clinical results (author's transl)].
After dissection and cannulation of aorta and vena cava, the kidneys are washed out "in situ" with a cooling perfusion, avoiding any possibility of so-called warm ischaemia. The kidneys and their vessels, still attached to aorta and vena cava, are then en bloc removed, which enables a satisfactory preparation of the vessels for subsequent anastomosis to be performed. After an experimental study [6], four kidneys were removed according to this procedure, and transplanted after an average cold-storage time of 23 hours. Diuresis recovery was immediate, and normalization of serum creatinin, and of urinary sodium and potassium levels, was achieved within 6 days.
D000293:Adolescent; D001011:Aorta; D002404:Catheterization; D003080:Cold Temperature; D006801:Humans; D016030:Kidney Transplantation; D009926:Organ Preservation / Q000379:methods*; D014021:Tissue Preservation / Q000379:methods*; D014184:Transplantation, Homologous; D014684:Venae Cavae
Prélèvement des reins chez l'homme sous réfrigération "in situ" par canulation aorto-cave. Technique, premiers résultats.