Use of hepatic cell cultures to detect and evaluate the mechanisms of action of toxic chemicals.
D000818:Animals; D002463:Cell Membrane Permeability; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured; D003584:Cytological Techniques; D004247:DNA / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D046911:Macromolecular Substances; D009154:Mutation; D051381:Rats; D014116:Toxicology / Q000379:methods*
D046911:Macromolecular Substances; D004247:DNA