Experimental candida-induced arteritis in mice. Relation to arteritis in the mucocutaneous lymph node syndrome.
An extract of Candida albicans isolated from a patient with typical mucocutaneous lymph node syndrome (MCLS) can produce coronary arteritis in a mouse when injected intraperitoneally. An unusual feature of this arteritis is that it is granulomatous, shows no fibrinoid change and is confined to the coronary arteries. These characteristics are quite similar to those found in patients with MCLS.
D000818:Animals; D000946:Antigens, Fungal; D001158:Arteries / Q000473:pathology; D001167:Arteritis / Q000209:etiology* / Q000473:pathology; D002176:Candida albicans / Q000276:immunology*; D003327:Coronary Disease / Q000209:etiology*; D005243:Feces / Q000382:microbiology; D006801:Humans; D008206:Lymphatic Diseases / Q000209:etiology*; D051379:Mice; D009080:Mucocutaneous Lymph Node Syndrome / Q000209:etiology* / Q000382:microbiology
D000946:Antigens, Fungal