Mutagenicity of the mycotoxin emodin in the salmonella/microsome system.
The mycotoxin emodin was found to be a frameshift mutagen for Salmonella typhimurium strain TA 1537 after metabolic activation in a mammalian microsome system.
D000818:Animals; D000880:Anthraquinones / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D004642:Emodin / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000378:metabolism; D009153:Mutagens; D009154:Mutation; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000235:genetics
D000880:Anthraquinones; D009153:Mutagens; D004642:Emodin