[Serological demonstration of a Treponema pallidum reinfection].
An improved method for precise separation of 19-S-IgM from other immunoglobulines reveals the reappearance of antitreponemal 19-S-IgM-antibodies after reinfection in five patients. The IgM-FTA-ABS-test with non-separated full-serum was non-reactive in all cases due to competitive inhibition. The new assay apparently permits a clear differentiation between reinfection and non-specific increase of titers in lipoidal antigen tests. Treatment failures can be distinguished from reinfections in cases where this method can continuously be applied.
D000328:Adult; D000918:Antibody Specificity; D001317:Austria; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D013587:Syphilis / Q000453:epidemiology; D013588:Syphilis Serodiagnosis / Q000379:methods*; D014210:Treponema pallidum / Q000276:immunology
D007075:Immunoglobulin M
Serologischer Nachweis einer Reinfektion mit Treponema pallidum.