title: The antioxidant vitamins.
abstract: This article is an attempt to study the metabolic functions of vitamin C and E together. Such a study must necessarily be imcomplete owing to the extreme richness of the literature. The increasing importance of the work on free radical reactions, their toxicity and carcinogenic action, and also their relation to the metabolism of metals, particularly iron, copper, selenium, and zinc, shows a number of metabolic pathways with which both vitamins interact. It is hoped that this article will indicate future research possibilities.
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D001205:Ascorbic Acid / Q000378:metabolism* / Q000627:therapeutic use; D001206:Ascorbic Acid Deficiency / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D003683:Dehydroascorbic Acid; D005231:Fatty Acids, Unsaturated / Q000378:metabolism; D005260:Female; D005298:Fertility / Q000187:drug effects; D005504:Food Analysis; D005511:Food Handling; D005609:Free Radicals; D006358:Hot Temperature; D006801:Humans; D008658:Inactivation, Metabolic; D007962:Leukocytes / Q000378:metabolism; D008297:Male; D009751:Nutritional Requirements; D011247:Pregnancy; D012737:Sex Factors; D013045:Species Specificity; D013329:Structure-Activity Relationship; D014131:Trace Elements / Q000378:metabolism; D014810:Vitamin E / Q000378:metabolism* / Q000627:therapeutic use; D014811:Vitamin E Deficiency / Q000378:metabolism
chemical_list: D000975:Antioxidants; D005231:Fatty Acids, Unsaturated; D005609:Free Radicals; D014131:Trace Elements; D014810:Vitamin E; D001205:Ascorbic Acid; D003683:Dehydroascorbic Acid