title: Acetate oxidation by bloodstream forms of Trypanosoma cruzi.
abstract: Bloodstream forms of Trypanosoma cruzi had a substantial increase in respiration in the presence of acetate. Oxidation of acetate took place via the tricarboxylic acid cycle and involved an antimycin A-sensitive respiratory pathway. Oxygen uptake in the presence of acetate was a sensitive to antimycin A inhibition as was CO2 production. There was a 6--7% residual O2 uptake which was not inhibited by high antimycin concentrations. Human anti-T. cruzi sera had no effect on oxygen uptake.
mesh_terms: D000085:Acetates / Q000378:metabolism*; D000818:Animals; D000937:Antigen-Antibody Reactions; D000968:Antimycin A / Q000494:pharmacology; D001769:Blood / Q000469:parasitology; D007106:Immune Sera; D051379:Mice; D010084:Oxidation-Reduction; D010101:Oxygen Consumption; D014349:Trypanosoma cruzi / Q000276:immunology / Q000378:metabolism*
chemical_list: D000085:Acetates; D007106:Immune Sera; D000968:Antimycin A