title: Metabolic products of microorganisms. 181. Chitin synthase from fungi, a test model for substances with insecticidal properties.
abstract: Chitin synthase from Coprinus cinereus (Schaeff. ex Fr.) S. F. Gray (= C. lagopus sensu Buller) was used as a model for chitin synthase from insects. The effect of dimilin (difluorobenzuron), captan (trichloromethylsulfonyl fungicide), kitazin P (organophosphorus ester fungicide) and parathion (organophosphorus insecticide) on the fungal enzyme was compared with the effect of nikkomycin (nucleosidepeptide antibiotic).
mesh_terms: D000363:Agaricales / Q000201:enzymology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002215:Captan / Q000494:pharmacology; D002687:Chitin Synthase / Q000037:antagonists & inhibitors*; D003302:Coprinus / Q000201:enzymology*; D004132:Diflubenzuron / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical; D005659:Fungicides, Industrial / Q000494:pharmacology*; D005964:Glucosyltransferases / Q000037:antagonists & inhibitors*; D007300:Insect Control; D007306:Insecticides / Q000494:pharmacology*; D008956:Models, Chemical; D009705:Nucleosides / Q000494:pharmacology; D010278:Parathion / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D005659:Fungicides, Industrial; D007306:Insecticides; D009705:Nucleosides; D010278:Parathion; D005964:Glucosyltransferases; D002687:Chitin Synthase; D002215:Captan; D004132:Diflubenzuron