Prophylactic and therapeutic activity of Rofenaid-40A in an experimental Escherichia coli airsac infection in chickens.
Rofenaid at a 0.02% dose level in feed was effective prophylactically and therapeutically against an experimentally induced Escherichia coli airsac infection in chickens. The activity of Rofenaid compared very favorably with that of the approved dose level of NF-180. Furthermore, the prophylactic use of Rofenaid did not interfere with the therapeutic efficacy of NF-180.
D000400:Air Sacs / Q000382:microbiology; D000818:Animals; D001835:Body Weight; D002645:Chickens; D004926:Escherichia coli / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*; D011201:Poultry Diseases / Q000188:drug therapy / Q000382:microbiology / Q000517:prevention & control*; D011743:Pyrimidines / Q000627:therapeutic use*; D012141:Respiratory Tract Infections / Q000382:microbiology / Q000662:veterinary*; D013412:Sulfadimethoxine / Q000627:therapeutic use*
D011743:Pyrimidines; D013412:Sulfadimethoxine