A study of paired necro kidney grafts.
The comparison of the fate of kidney pairs originating from the same donor offers an opportunity to control variability in primary kidney graft survival due to characteristics of the donor. The present study on 1,303 pairs was made possible by combining the information in the Scandiatransplant registry and the EDTA follow-up file. The analysis showed that, contrary to expectation, the main variability in kidney graft survival is not donor dependent but rather due to post-nephrectomy factors. By the present approach it was possible to demonstrate a significant effect of presensitisation, HLA-A,B matching and recipient age. In contrast, transportation, and differences in sex and ABO blood group combinations seem to be of no importance for kidney graft survival.
D000017:ABO Blood-Group System; D000206:Actuarial Analysis; D000375:Aging; D000906:Antibodies; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006680:HLA Antigens; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D009392:Nephrectomy
D000017:ABO Blood-Group System; D000906:Antibodies; D006680:HLA Antigens