title: Induction of mutations by photodynamic action of thiopyronine in Saccharomyces cerevisiae.
abstract: The induction of cytoplasmic and nuclear mutations by the photodynamic action of thiopyronine is demonstrated in a haploid strain of Saccharomyces cerevisiae that has been isolated as a photodynamic sensitive mutant. No significant increase in corresponding mutation frequencies could be observed in a strain resistant to photodynamic inactivation by thiopyronine.
mesh_terms: D002467:Cell Nucleus / Q000187:drug effects; D003593:Cytoplasm / Q000187:drug effects; D006238:Haploidy; D009154:Mutation; D010777:Photochemistry; D010787:Photosensitivity Disorders / Q000139:chemically induced; D011754:Pyronine / Q000031:analogs & derivatives; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development; D014966:Xanthenes / Q000031:analogs & derivatives
chemical_list: D014966:Xanthenes; D011754:Pyronine