[Immune-haematological diagnosis of neonatal immunothrombocytopenia (author's transl)].
The diagnosis of immunologically caused platelet deficiencies in newborn infants requires use of methods permitting demonstration of platelet auto- and allo-zntibodies, complete and incomplete antibodies. Taking the well known differentiation of neonatal immunothrombocytopenias into auto- and allo-immune diseases as a basis, the immune-haematological findings in eight cases are reported. For the first time two cases are reported in which both idiopathic thrombocytopenic purpura of the mother was known and allo-immunisation against paternal HLA antigens of the child could be demonstrated.
D001323:Autoantibodies / Q000032:analysis; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D007158:Immunologic Techniques; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis / Q000276:immunology*; D008297:Male; D013921:Thrombocytopenia / Q000175:diagnosis / Q000276:immunology*
D001323:Autoantibodies; D006680:HLA Antigens
Die immunhämatologische Diagnostik neonataler Immunthrombozytopenien.