title: Mutagenic activity of furfural in Salmonella typhimurium TA100.
abstract: The mutagenic activity of furfural was tested in Salmonella typhimurium strains TA98 and TA100. Furfural produced mutations in the TA100 strain, but not in the TA98 strain. A rat-liver microsomal fraction did not increase the mutagenic activity of furfural in either strain. Mutagenic activity of furfural in the TA100 strain was not increased by benzo[alpha]pyrene in the presence of metabolic activation.
mesh_terms: D001580:Benzopyrenes / Q000494:pharmacology; D001711:Biotransformation; D005662:Furaldehyde / Q000494:pharmacology*; D005821:Genetic Techniques; D009153:Mutagens; D012486:Salmonella typhimurium / Q000235:genetics
chemical_list: D001580:Benzopyrenes; D009153:Mutagens; D005662:Furaldehyde