The evidence that salt is an important aetiological agent, if not the cause, of hypertension.
1. Salt intake and the incidence of hypertension correlate between populations. 2. Salt intake within a population may correlate with the incidence of hypertension. 3. Disorders that lead to retention of salt cause hypertension. 4. Modest salt restriction reduces blood pressure in many patients. 5. Reducing salt balance and preventing the compensatory rise in angiotensin II controls blood pressure in most patients. 6. Salt is the probable cause of the epidemic of hypertension in the Western world; this could be prevented by salt restriction.
D000450:Aldosterone / Q000097:blood; D006801:Humans; D006929:Hyperaldosteronism / Q000097:blood; D006973:Hypertension / Q000097:blood / Q000139:chemically induced*; D008901:Mineralocorticoids / Q000652:urine; D012083:Renin / Q000097:blood; D012306:Risk; D012964:Sodium / Q000097:blood; D012965:Sodium Chloride / Q000009:adverse effects*
D008901:Mineralocorticoids; D012965:Sodium Chloride; D000450:Aldosterone; D012964:Sodium; D012083:Renin