Identification in situ of T lymphocytes in the dermal and epidermal infiltrates of mycosis fungoides.
Frozen tissue sections from the lesions of five patients with histologically proven mycosis fungoides were examined using a specific antihuman T-cell antiserum and an indirect peroxidase staining technique. The dermal and epidermal infiltrates were shown to comprise predominantly cells bearing the specific T-cell antigen, HTLA. Two of the patients exhibited characteristic Pautrier microabscesses whose cells were exclusively T lymphocytes.
D000328:Adult; D000368:Aged; D004817:Epidermis / Q000276:immunology; D005260:Female; D005629:Frozen Sections; D006801:Humans; D007106:Immune Sera; D007124:Immunoenzyme Techniques; D008297:Male; D009182:Mycosis Fungoides / Q000276:immunology*; D012867:Skin / Q000276:immunology; D012878:Skin Neoplasms / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D007106:Immune Sera