title: [Vogt-Koyanagi syndrome. Therapeutic trial with corticosteroid].
abstract: A brazilian housewife, descendant of japanese (both parents), 37 years aged, affected with Vogt-Koyanagi's syndrome (uveitis, dysacousia, alopecia, madarosis, poliosis, vitiligo) was treated with prednisone. During the course and at the end of the treatment an almost complete regression of alopecia, poliosis, madarosis and a total involution of the dysacousia could be observed, meanwhile the vitiligo and the sequels of uveitis remained unchanged. Taking into account that Vogt-Koyanagi's syndrome is susceptible of expontaneous involution, no definitive conclusion about the efficiency of therapeutic agent may be drawn in this singular case. However, it must be considered as valid the possibility of a favourable action of a systemic treatment with corticosteroides in the initial stages of the disease chiefly for preventing its more harmful consequences, i.e. deafness and blindness.
mesh_terms: D000328:Adult; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D010859:Pigmentation Disorders / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use*; D013607:Tablets; D014605:Uveitis / Q000188:drug therapy*; D014607:Uveomeningoencephalitic Syndrome / Q000188:drug therapy*
chemical_list: D013607:Tablets; D011241:Prednisone
vernacular_title: Síndrome de Vogt-Koyanagi. Tentativa terapêutica com corticosteróide.