The relative roles of surgery and radiotherapy in the management of soft tissue sarcomas of adults. A personal appraisal.
The literature of the last 25 years pertaining to the treatment of sarcomas of the soft somatic tissues by surgery and radiotherapy, both separately and in combination, has been reviewed. Surgery alone, if it is to be successful in an appreciable proportion of cases, must be radical. There is a growing body of evidence which suggests that less-than-radical surgery in combination with postoperative radiotherapy may give results equal or superior to those of radical surgery alone. There is need for a multicentre controlled clinical trial to compare the results of the two modes of treatment.
D000328:Adult; D005354:Fibrosarcoma / Q000401:mortality; D006801:Humans; D008080:Liposarcoma / Q000401:mortality; D009364:Neoplasm Recurrence, Local; D011184:Postoperative Period; D012509:Sarcoma / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*