A comparison of ampicillin and amoxycillin in acute on chronic bronchitis.
Twenty-five patients with an acute exacerbation of chronic bronchitis completed a double-blind trial of amoxycillin 1.5 g v ampicillin 4 g daily. After treatment for one week there was no difference between the treatments in the rates of achieving mucoid sputum, reduction in sputum volume, improvement in peak expiratory flow rate, or duration of hospital stay. In the doses studied ampicillin and amoxycillin are effective drugs of about equal cost.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000658:Amoxicillin / Q000627:therapeutic use*; D000667:Ampicillin / Q000494:pharmacology / Q000627:therapeutic use*; D001991:Bronchitis / Q000188:drug therapy*; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004341:Drug Evaluation; D005540:Forced Expiratory Flow Rates; D006801:Humans; D008875:Middle Aged; D013183:Sputum / Q000187:drug effects
D000667:Ampicillin; D000658:Amoxicillin