title: Influence of metoprolol, alone and in combination with a thiazide diuretic, on blood pressure, plasma volume, extracellular volume and glomerular filtration rate in essential hypertension.
mesh_terms: D000328:Adult; D001581:Benzothiadiazines; D001794:Blood Pressure / Q000187:drug effects; D001835:Body Weight; D002986:Clinical Trials as Topic; D004232:Diuretics; D004359:Drug Therapy, Combination; D005110:Extracellular Space / Q000187:drug effects; D005260:Female; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008790:Metoprolol / Q000494:pharmacology / Q000627:therapeutic use*; D008875:Middle Aged; D010953:Plasma Volume / Q000187:drug effects; D011412:Propanolamines / Q000627:therapeutic use*; D049993:Sodium Chloride Symporter Inhibitors / Q000627:therapeutic use*
chemical_list: D001581:Benzothiadiazines; D004232:Diuretics; D011412:Propanolamines; D049993:Sodium Chloride Symporter Inhibitors; D008790:Metoprolol