Estimation of tubule or cylinder LV, SV and VV on thick sections.
The estimators of tubule or cylinder LV = 2NA, SV = 2IL, and VV = PP are considered in terms of bias due to section thickness, diameter, overlap, and grazing or fuzzy profiles. The superiority in a number of cases of the indirect estimation of SV and VV as functions of LV and profile diameter is discussed. Statistical aspects are dealt with in a practical example.
D000818:Animals; D006652:Histological Techniques; D007684:Kidney Tubules / Q000648:ultrastructure; D008433:Mathematics; D008854:Microscopy, Electron; D008871:Microvilli / Q000648:ultrastructure; D008954:Models, Biological; D051381:Rats