Thiamin biosynthesis in Saccharomyces cerevisiae. Origin of carbon-2 of the thiazole moiety.
Radioactivity from [2-14C]glycine enters C-2 of the thiazole moiety of thiamin and no other site, in Saccharomyces cerevisiae (strains A.T.C.C. 24903 and 39916, H.J. Bunker). Radioactivity from L-[Me-14C]methionine or from DL-[2-14C]tyrosine does not enter thiamin.
D002250:Carbon Radioisotopes; D055598:Chemical Phenomena; D002621:Chemistry; D005998:Glycine / Q000378:metabolism; D008715:Methionine / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D013831:Thiamine / Q000096:biosynthesis*; D013844:Thiazoles / Q000378:metabolism; D014443:Tyrosine / Q000378:metabolism
D002250:Carbon Radioisotopes; D013844:Thiazoles; D014443:Tyrosine; D008715:Methionine; D005998:Glycine; D013831:Thiamine