Thalassemia major terminating in a non-Hodgkin B-cell lymphoma: report of a case.
A large noncleaved diffuse follicular center cell lymphoma occurring in an 11-year-old child with homozygous beta thalassemia is described. The possible relationship between numerous blood transfusions during a 10-year period and the occurrence of a B-cell lymphoma is discussed.
D001402:B-Lymphocytes / Q000166:cytology; D002471:Cell Transformation, Neoplastic; D002648:Child; D006258:Head and Neck Neoplasms / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007158:Immunologic Techniques; D007945:Leukemia, Lymphoid / Q000150:complications*; D008223:Lymphoma / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology; D013789:Thalassemia / Q000150:complications* / Q000628:therapy; D065227:Transfusion Reaction