A rapid method for electron microscopic examination of blood cells.
A method is described whereby the time required for the processing of white blood cells for electron microscopy can be shortened from 36 to 3 1/2 hours. Because cells of the peripheral blood are not attached to each other, fixation, dehydration, and infiltration of the embedding medium is more rapid. This makes it possible for clinicians to use fine structural data for diagnosis as illustrated in three cases.
D000328:Adult; D000368:Aged; D003584:Cytological Techniques; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000097:blood; D007962:Leukocytes / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron / Q000379:methods; D008875:Middle Aged; D012751:Sezary Syndrome / Q000097:blood; D013997:Time Factors