[Comparative study of the gastric response in rats with pyloric ligation -- normovolemic rats and rats made hypovolemic by acute hemorrhage -- subjected to hypoxia].
Gastric secretion was studied in two groups of rats in which pyloric ligature was made according to Dai's method. Both groups were put in a hypopressure chamber. One of the groups was normovolemic. The other group was made hypovolemic by acute bleeding. The following parameters were checked in gastire contents: volumen, acid and pepsin secretion, U.P./g. of stomach, chloride, potassium and sodium; in gastric mucosa total U.P. and pepsinogen concentration were measured. In the rats subjected to acute hypovolemia and hypoxia it was found a significant decrease in acid secretion, chloride and potassium mEq/1; there were no statistically significant changes in volume, pepsin secretion; U.P./g. of stomach and sodium mEq/1. Total U. P. and U.P./. of stomach increased in the gastirc mucosa.
D000818:Animals; D001810:Blood Volume; D002712:Chlorides / Q000032:analysis; D005260:Female; D005750:Gastric Juice / Q000032:analysis / Q000378:metabolism*; D005753:Gastric Mucosa / Q000032:analysis; D000860:Hypoxia / Q000503:physiopathology*; D008026:Ligation; D008297:Male; D010434:Pepsin A / Q000032:analysis; D010435:Pepsinogens / Q000032:analysis; D011188:Potassium / Q000032:analysis; D011708:Pylorus / Q000502:physiology*; D051381:Rats
D002712:Chlorides; D010435:Pepsinogens; D010434:Pepsin A; D011188:Potassium
Estudio comparativo de la respuesta gástrica en ratas con piloro ligado, normovolémicas e hipovolémicas por hemorragia aguda, sometidas a hipoxia.