Subtotal body irradiation with linear accelerator as preparation for marrow engraftment in aplastic anemia.
Two cases of multitransfused severe aplastic anemia were retransplanted with bone marrow from the same HLA compatible sibling donors after subtotal body irradiation (800 r). Only minor non hematologic toxicity was observed. No permanent take was seen in relation to this procedure. During the survival time of the patients (78-120 days) no signs of interstitial pneumonia were observed.
D000741:Anemia, Aplastic / Q000628:therapy*; D016026:Bone Marrow Transplantation; D003520:Cyclophosphamide / Q000627:therapeutic use; D006084:Graft Rejection / Q000528:radiation effects; D006801:Humans; D011344:Procarbazine / Q000627:therapeutic use; D011878:Radiotherapy / Q000379:methods; D011879:Radiotherapy Dosage; D014184:Transplantation, Homologous
D011344:Procarbazine; D003520:Cyclophosphamide