Determination of iodide in metabolic studies of 125I-labeled compounds.
Methods capable of measuring inorganic iodide in the presence of other highly polar metabolites were developed in support of studies concerning the metabolism of 125I-labeled compounds. The methods included separation of iodine on a weakly basic resin paper followed by gamma-counting, methyl iodide exchange, and reverse isotopic dilution.
D000818:Animals; D001713:Biphenyl Compounds / Q000378:metabolism; D002854:Chromatography, Paper; D006847:Hydrocarbons, Iodinated / Q000378:metabolism; D007454:Iodides / Q000032:analysis* / Q000652:urine; D007457:Iodine Radioisotopes; D008722:Methods; D011865:Radioisotope Dilution Technique; D051381:Rats
D001713:Biphenyl Compounds; D006847:Hydrocarbons, Iodinated; D007454:Iodides; D007457:Iodine Radioisotopes