The generation of TXA2 in human platelet rich plasma and its inhibition by nictindole and prostacyclin.
D000244:Adenosine Diphosphate / Q000494:pharmacology; D001095:Arachidonic Acids / Q000494:pharmacology; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D003094:Collagen / Q000494:pharmacology; D004837:Epinephrine / Q000494:pharmacology; D011464:Epoprostenol / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D007211:Indoles / Q000494:pharmacology*; D010088:Oxidoreductases / Q000037:antagonists & inhibitors*; D010974:Platelet Aggregation / Q000187:drug effects; D011453:Prostaglandins / Q000494:pharmacology*; D011725:Pyridines / Q000494:pharmacology; D013917:Thrombin / Q000494:pharmacology; D013928:Thromboxane A2 / Q000097:blood*; D013930:Thromboxane-A Synthase / Q000037:antagonists & inhibitors*; D013931:Thromboxanes / Q000097:blood*
D001095:Arachidonic Acids; D007211:Indoles; D011453:Prostaglandins; D011725:Pyridines; D013931:Thromboxanes; D013928:Thromboxane A2; D000244:Adenosine Diphosphate; D003094:Collagen; D011464:Epoprostenol; D010088:Oxidoreductases; D013917:Thrombin; D013930:Thromboxane-A Synthase; C002092:nictindole; D004837:Epinephrine