[Investigations on the antimicrobial activity of amine-aldehyde-condensates. 6. Communication: azomethines of substituted benzaldehydes (author's transl)].
In the scope of our research about the antimicrobial activity of amin-aldehydecondensates a number of substituted benzaldehyde azomethines was synthesized by condensation of suitable benzaldehydes with primary amines (aminoethanol and n-butylamine). Structures and physical constants are shown in the table 1. The antimicrobial activity is demonstrated by the results of the disk-test (table 2 and 3), of the minimal inhibition concentration test (MIC, table 4) and of the suspension-disinfecting test following the method of the DGHM (table 5). It may be shown that both the germistatic and the germicidal activity depends on the substituents of the aromatic ring. Bactericidal activity show the test compounds mainly versus the gram-negative bacteria.
D000447:Aldehydes; D000588:Amines; D000935:Antifungal Agents / Q000592:standards*; D002176:Candida albicans / Q000187:drug effects; D004202:Disinfectants / Q000592:standards*; D007709:Klebsiella / Q000187:drug effects
D000447:Aldehydes; D000588:Amines; D000935:Antifungal Agents; D004202:Disinfectants
Untersuchungen zur antimikrobiellen Wirksamkeit von Amin-Aldehydkondensaten. 6. Mitteilung: Azomethine substituierter Benzaldehyde.