The fate of fertilized ova in rats receiving luteinizing hormone-releasing hormone (LRH).
The development and eventual fate of unimplanted fertilized ova in rats receiving pregnancy-inhibiting doses of luteinizing hormone-releasing hormone (LRH) were studied during the first 14 days of gestation. The results suggest that LRH accelerates passage of ova through the oviducts. Also, the zona pellucida of treated animals is retained by the majority of ova until day 7; zona-encased ova were observed as late as day 10. Elimination of the ova appears to occur by expulsion with uterine fluids through the vagina upon the animals' return to estrus.
D000818:Animals; D001755:Blastocyst; D010064:Embryo Implantation / Q000187:drug effects; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D010060:Ovulation / Q000187:drug effects; D010063:Ovum / Q000166:cytology; D011247:Pregnancy; D051381:Rats; D015044:Zona Pellucida; D015053:Zygote / Q000187:drug effects*
D007987:Gonadotropin-Releasing Hormone