Detection of enterotoxigenic and invasive strains of Yersinia enterocolitica.
Membrane filtrates and heavy cell suspensions of 11 strains of Yersinia enterocolitica isolated from a recent epidemic were examined respectively for enterotoxin activity and tissue invasiveness. Although no heat-labile enterotoxins were detected, some strains were found to possess heat-stable enterotoxins and to have the ability to penetrate the conjunctival epithelia of guinea pig eyes. These activites were detected only in cultures grown at 25 degrees C and not at 36 degrees C.
D000311:Adrenal Glands; D000818:Animals; D001431:Bacteriological Techniques; D002460:Cell Line; D004196:Disease Outbreaks; D004768:Enterotoxins / Q000096:biosynthesis*; D006168:Guinea Pigs; D007637:Keratoconjunctivitis / Q000209:etiology; D051379:Mice; D013045:Species Specificity; D014774:Virulence; D015007:Yersinia / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism*; D015009:Yersinia Infections / Q000382:microbiology
D004768:Enterotoxins