[Liver and ovulation inhibitors. Effects on liver function of estrogen-progestagen containing steroid oral contraceptives].
Since introduction of oral contraceptive steroids a variety of physiologic-adaptive and toxic side effects have been reported. -a review is given. The study reports also four cases of hepatic vein thrombosis (Budd-Chiari-Syndrome--Venoocclusive disease) and three cases of benign hepatic tumors (liver cell adenoma and focal nodular hyperplasia) in young women following 2- to 5-year treatment with oral contraceptive steroids.
D000236:Adenoma / Q000209:etiology; D000328:Adult; D006502:Budd-Chiari Syndrome / Q000209:etiology; D003276:Contraceptives, Oral / Q000009:adverse effects*; D003277:Contraceptives, Oral, Combined / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000209:etiology; D010060:Ovulation / Q000187:drug effects
D003276:Contraceptives, Oral; D003277:Contraceptives, Oral, Combined
Leber und Ovulationshemmer. Zur leberschädigenden Wirkung der Ostrogen-Progestagen-haltigen oralen kontrazeptiven Steroide.