[Results of a study of the reactogenicity and epidemiological effectiveness of a 2d revaccination against whooping cough].
The reactogenicity and epidemiological effectiveness of the second revaccination against pertussis were studied in conformity with all the conditions of a controlled epidemiological trial. The character of the distribution of local and fever reactions in children aged 6 years after the second revaccination with adsorbed DTP vaccine suggests the presence of high sensitivity to the pertussis component of absorbed DTP vaccine in children of this age group. The results obtained from the study of epidemiological effectiveness (in 15,621 children) indicated that the second revaccination of children aged 6 years (at an interval of 3 or more years after the first revaccination) was not advisable as it did not influence noticeably the pertussis incidence.
D000327:Adsorption; D002648:Child; D002986:Clinical Trials as Topic; D004168:Diphtheria Toxoid / Q000008:administration & dosage; D004338:Drug Combinations; D004341:Drug Evaluation; D006801:Humans; D007117:Immunization, Secondary / Q000009:adverse effects; D010567:Pertussis Vaccine / Q000008:administration & dosage; D013745:Tetanus Toxoid / Q000008:administration & dosage; D013997:Time Factors; D014586:USSR; D014505:Urban Population; D014611:Vaccination / Q000009:adverse effects; D014917:Whooping Cough / Q000517:prevention & control*
D004168:Diphtheria Toxoid; D004338:Drug Combinations; D010567:Pertussis Vaccine; D013745:Tetanus Toxoid
Rezul'taty izucheniia reaktogennosti i épidemiologicheskoĭ éffektivnosti II revaktsinatsii protiv kokliusha.