title: Bacterial infection in relation to pain and irregular bleeding in women using IUD.
abstract: Pain and metrorrhagia in women using IUDs are often the reason for removing the IUD. In 54 women where the IUD was removed, uterine fluid for bacteriologic cultures was taken from the removed IUD. There was a correlation between positive cultures and symptoms of pain and metrorrhagia. Spotty bleeding caused by microtraumata and increased fibrinolytic activity of the IUD might thus consitute a substrate for bacterial invasion resulting in endometritis and in turn increased bleeding and pain. In 18 male consorts of females with positive cultures, asymptomatic bacteriospermia was found. Treatment offered alleviated symptoms. Removal of the IUD need thus not be necessary.
mesh_terms: D001424:Bacterial Infections / Q000150:complications*; D004754:Enterobacter / Q000472:pathogenicity; D004926:Escherichia coli / Q000472:pathogenicity; D005260:Female; D006801:Humans; D007434:Intrauterine Devices / Q000009:adverse effects*; D007709:Klebsiella / Q000472:pathogenicity; D007778:Lactobacillus / Q000472:pathogenicity; D008297:Male; D008796:Metrorrhagia / Q000209:etiology*; D010146:Pain / Q000209:etiology*; D013210:Staphylococcus / Q000472:pathogenicity; D013291:Streptococcus / Q000472:pathogenicity