[Viral hypothesis of multiple sclerosis: new aspects].
A review is presented of the epidemiological and serological data on which the viral hypothesis of multiple sclerosis is based. Recent experiments investigating the capacity of viruses to establish chronic infections are presented as a model to explain the clinical course of the disease. Finally, studies of the molecular interactions of vaccinia virus with the myelin membrane serve as a basis on which to discuss the problem of the mechanism of demyelination.
D003711:Demyelinating Diseases / Q000503:physiopathology; D006801:Humans; D008967:Molecular Biology; D009103:Multiple Sclerosis / Q000097:blood / Q000453:epidemiology / Q000382:microbiology*; D009186:Myelin Sheath / Q000382:microbiology; D014616:Vaccinia virus / Q000472:pathogenicity; D014777:Virus Diseases
Hypothèse virale de la sclérose en plaques: nouveaux aspects.