title: [Multiple eccrine spiradenomas. Apropos of 2 cases in 2 sisters].
abstract: Two cases of multiple eccrine spiradenoma were studied, representing respectively up to the present time the 7th and 8th registered cases in the world literature. These cases two are siblings, a fact that had never been observed before. The histogenesis of the tumour has been the subject of controversy. The presence of multiple lesions in each patient and the incidence in siblings are two important points in favour of the naevic character of eccrine spiradenoma. Among other therapeutic measures we wish to draw attention to the excellent result we obtained with small doses of radiotherapy (1,500 rads divided in ten applications). It should be kept in mind that remission of the disease may only be temporary.
mesh_terms: D000236:Adenoma / Q000235:genetics* / Q000473:pathology; D000328:Adult; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000235:genetics* / Q000473:pathology; D013544:Sweat Gland Neoplasms / Q000235:genetics* / Q000473:pathology
vernacular_title: Espiradenomas écrinos múltiplos. A propósito de dois casos em irmãs.