[Detection of B-cell antigen on the blast cells in chronic myeloid leukemia].
The presence of the common antigen on B lymphocytes of healthy donors and myeloblasts of patients with chronic myeloid leukemia in blastic crisis was observed with antimyeloblastic serum in the indirect surface immunofluorescence test. The cytotoxic test showed this antigen in the blastic cells in 27 out of 57 patients with CML BC, in 3 of 11 patients with acute lymphoid leukemia, in 1 of 8 patients with chronic lymphoid leukemia and in 2 of 2 patients with undifferentiated leukemia. The antigen was not found in the peripheral blood cells of healthy donors.
D000951:Antigens, Neoplasm / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis*; D001402:B-Lymphocytes / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic / Q000379:methods; D005455:Fluorescent Antibody Technique; D006801:Humans; D007106:Immune Sera; D007951:Leukemia, Myeloid / Q000276:immunology*
D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D007106:Immune Sera
Obnaruzhenie B-kletochnogo antigena na blastnykh kletkakh bol'nykh khronicheskim mieloidnym leĭkozom.