title: Prejudices in pharmacology and pharmacotherapy: reserpine as a model for experimental research in depression.
abstract: The choice of reserpine as practically the sole model substance used in research in depression over two decades was not dictated by rational considerations alone: hypothetical notions, prospects of the rapid realization of experimental research aims and the fascination of the exotic origin of this "natural" drug made a significant contribution.
mesh_terms: D002395:Catecholamines / Q000378:metabolism; D003863:Depression / Q000139:chemically induced*; D004195:Disease Models, Animal; D049673:History, 20th Century; D006801:Humans; D011600:Psychopharmacology / Q000379:methods*; D012107:Research Design; D012110:Reserpine / Q000266:history / Q000494:pharmacology*
chemical_list: D002395:Catecholamines; D012110:Reserpine