Hematologic perturbations associated with salicylate.
Interactions of salicylates with the hematopoietic system are reviewed. Development of anemia is discussed with respect to fluid retention, gastrointestinal bleeding, and hemolytic anemia. Alterations in polymorphonuclear leukocyte and platelet function are evaluated. Interactions with anticoagulants and with the coagulation system are identified.
D001241:Aspirin / Q000009:adverse effects*; D001792:Blood Platelets / Q000502:physiology; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced; D006402:Hematologic Diseases / Q000139:chemically induced*; D006413:Hematopoietic System / Q000187:drug effects; D006461:Hemolysis / Q000187:drug effects; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D007962:Leukocytes / Q000502:physiology; D012459:Salicylates / Q000009:adverse effects*
D012459:Salicylates; D001241:Aspirin