["Old new" problem of the lues risk in transfusion medicine: the effect of the serum and ACD stabilizer at different temperatures on the infectiosity of Treponema pallidium (Nichols strain)].
The portion of warm and fresh blood transfusions had increased obviously. This is accompanied by a decrease of the restrictive period of the former 72 and the presently 48 hours for blood units to be transfused. Therefore, the danger of a symphilis transmitted by transfusion is impending again. This is realized insufficiently and the syphilis may occur, if blood is drawn in the seronegative phase of the primary stage of syphilis and transfused within the restrictive period. Model trials on the infectivity of Treponema pallidum revealed that the syphilis cannot be transmitted by blood and its derivates drawn in the seronegative phase after storage at 4 degrees C for 24 hours. Therefore, the reduction of the restrictive period to 48 hours is justified.
D000818:Animals; D001769:Blood / Q000382:microbiology*; D001793:Blood Preservation; D002951:Citrates / Q000494:pharmacology*; D005947:Glucose / Q000494:pharmacology*; D006801:Humans; D011817:Rabbits; D012306:Risk; D012996:Solutions; D013587:Syphilis / Q000635:transmission*; D013696:Temperature; D013997:Time Factors; D065227:Transfusion Reaction; D014210:Treponema pallidum / Q000472:pathogenicity*
D002951:Citrates; D012996:Solutions; D005947:Glucose
Zum "alten neuen" Problem des Luesrisikos in der Transfusionsmedizin: Einfluss von Serum und ACD-Stabilisator bei verschiedenen Temperaturen auf die Infektiosität von Treponema pallidum (Stamm Nichols).