[Detection of blood group P1 activity in F. hepatica and F. gigantica (author's transl)].
Four lyophilizated liver flüke antigens and one of hydatid fluid were examined for the presence of blood group like antigens P1, A, B, M and N by an hemagglutination inhibition test with hyperimmune and natural hemagglutinating sera. P1 or P1-like substance was found in the extracts of "Fasciola hepatica" and "F. gigantica" in a lower concentration than in echinoccocal fluid. This presence may explain the occurrence of anti-P1 antibodies in patients infected with liver flüke and belonging to the P2 blood group. However biochemical studies will be necessary to determine if the P1 activity is due to the blood group P1 substance of the red cell itself or due to a P1 like substance.
D000818:Animals; D000941:Antigens / Q000032:analysis*; D001789:Blood Group Antigens / Q000276:immunology*; D005209:Fasciola / Q000276:immunology*; D005210:Fasciola hepatica / Q000276:immunology; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D010127:P Blood-Group System / Q000276:immunology*
D000941:Antigens; D001789:Blood Group Antigens; D010127:P Blood-Group System
Mise en évidence de substance P1 ou P1-like dans Fasciola hepatica et Fasciola gigantica.