Mitochondrial mutagenesis in Saccharomyces cerevisiae. I. Ultraviolet radiation.
UV efficiently induces mutations in mitDNA , conferring resistance to erythromycin. Mitochondrial chloramphenicol-resistant mutants are probably also induced by UV, but almost 90% of mutants with such phenotype are non-mitochondrial; therefore it is possible to estimate accurately the frequences of the induced presumptive mitochondrial capr mutations.
D002701:Chloramphenicol / Q000494:pharmacology; D004247:DNA / Q000528:radiation effects*; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000494:pharmacology; D008928:Mitochondria / Q000528:radiation effects*; D009154:Mutation; D010641:Phenotype; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D014466:Ultraviolet Rays
D004917:Erythromycin; D002701:Chloramphenicol; D004247:DNA