[Morphological and immunofluorescent studies of the leukocytes in blood smears in hepatitis A and B and chronic liver diseases].
Morphological examination of leukocytes in blood smears from patients with viral hepatitis A and B revealed up to 34% of atypical lymphocytes (AL) in the form of cells of irregular shape with the wide basophilic cytoplasm. Their number reached maximum by the 9th--14th day of the disease and decreased to 8% by 40--50 days. The number of AL was significantly higher during the high activity of the process both in acute and chronic forms of viral hepatitis A and B. In normal subjects as well as in patients with chronic hepatitis of alcoholic etiology the amount of AL did not exceed 6%. Immunofluorescent studies with gammaglobulin from convalescents after viral hepatitis A demonstrated fluorescence of the leukocyte cytoplasm in 86.3% of blood smears from patients with viral hepatitis both early in the disease and at 14--20 days in infectious hepatitis A (in controls no more than 6%). Fluorescence was demonstrated in 70.1% of cases in examinations of blood smears from patients with chronic liver diseases of viral etiology.
D000328:Adult; D002648:Child; D005455:Fluorescent Antibody Technique; D006506:Hepatitis A / Q000097:blood / Q000175:diagnosis*; D006509:Hepatitis B / Q000097:blood / Q000175:diagnosis*; D006519:Hepatitis, Alcoholic / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D007962:Leukocytes / Q000276:immunology / Q000473:pathology; D008103:Liver Cirrhosis / Q000097:blood / Q000175:diagnosis*
Morfologicheskoe i immunofliuorestsentnoe issledovaniia leikotsitov v mazkakh krovi pri virusnykh gepatitakh A i B i khronicheskikh zabolevaniiakh pecheni.