Antigenic activity in adult Dipetalonema viteae in the indirect immunofluorescent test against sera from filariasis patients--the immunofluorescent histological search for "pure" antigen.
Using IFAT, it has been shown that isolated egg-shells and uterine fluid of Dipetalonema viteae are the most potent antigens in heterologous systems using human sera from patients infected with Wuchereria bancrofti, Onchocerca volvulus and Loa loa, as well as in homologous systems using sera from animals infected with D. viteae. It is suggested that these antigens are unlikely to be highly species-specific, and that anatomical isolation of antigens is a necessary prerequisite to immunochemical analysis aimed at the preparation of a "pure" antigen.
D000818:Animals; D000941:Antigens / Q000302:isolation & purification*; D004153:Dipetalonema / Q000276:immunology*; D005368:Filariasis / Q000175:diagnosis / Q000276:immunology; D005455:Fluorescent Antibody Technique; D013045:Species Specificity
D000941:Antigens