Preliminary studies on cholinergic control of pituitary gonadotrophin secretion in the ewe.
Administration of neostigmine, a cholinomimetic, to anoestrous ewes diminished the increase in jugular plasma luteinising hormone and follicle-stimulating hormone induced by oestradiol. Intravenous injection of atropine had no effect on the gonadotrophin surge.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D004958:Estradiol / Q000494:pharmacology; D004971:Estrus; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology; D006065:Gonadotropins, Pituitary / Q000097:blood*; D007986:Luteinizing Hormone / Q000097:blood; D009388:Neostigmine / Q000494:pharmacology; D010275:Parasympathetic Nervous System / Q000502:physiology*; D011247:Pregnancy; D011950:Receptors, Cholinergic / Q000187:drug effects; D012756:Sheep / Q000502:physiology*
D006065:Gonadotropins, Pituitary; D011950:Receptors, Cholinergic; D007987:Gonadotropin-Releasing Hormone; D009388:Neostigmine; D004958:Estradiol; D001285:Atropine; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone