Torsion dystonia: a case with delayed remission following thalamotomy and phenothiazine therapy.
Torsion dystonia in 13-year-old girl progressed to severe opisthotonus and dystonic posturing of the limbs, accompanied by severe psychic changes, cachexia and calcification around joints. Drug therapy was ineffective. Ventrolateral thalamotomy and chlorpromazine brought about a delayed but remarkable amelioration of all symptoms and signs, still present 4 years later.
D000293:Adolescent; D002114:Calcinosis / Q000000981:diagnostic imaging; D002746:Chlorpromazine / Q000627:therapeutic use*; D004421:Dystonia / Q000188:drug therapy / Q000628:therapy*; D005260:Female; D006801:Humans; D011187:Posture; D011859:Radiography; D012075:Remission, Spontaneous; D013238:Stereotaxic Techniques; D013788:Thalamus / Q000601:surgery*; D013997:Time Factors
D002746:Chlorpromazine