The lack of mutagenic properties of patulin and patulin adducts formed with cysteine in Salmonella test systems.
The mutagenic properties of patulin and the patulin adducts formed with cysteine were tested with histidine auxotroph Salmonella typhimurium strains as indicator organisms. The tests were performed by microsomal activation and host-mediated assay. Neither patulin nor patulin--cysteine reaction mixture was mutagenic in these test systems.
D003545:Cysteine / Q000378:metabolism; D005821:Genetic Techniques; D009153:Mutagens; D010365:Patulin / Q000031:analogs & derivatives / Q000378:metabolism / Q000494:pharmacology*; D011714:Pyrans / Q000494:pharmacology*; D012486:Salmonella typhimurium / Q000235:genetics
D009153:Mutagens; D011714:Pyrans; D010365:Patulin; D003545:Cysteine