[Treatment of lithium tremor with the beta receptor blocker, pindolol].
In a cross-over study with Pindolol, 15 mg/day, against placebo, we studied during 4 weeks 22 patients aged between 20 and 65 years who where treated by means of lithium carbonate retard (Quilonum Retard). The tremor was measured twice a week by means of three apparative methods: an accelerometer, a 'hole-plate' and an 'aimed tapping plate', both constructed by Janke, and was also studied by means of a self-evaluation rating-scale. We obtained a positive therapeutic effect of Pindolol on lithium-induced tremor, which was statistically significant by means of the 'hole-plate' and of self-evaluation. Differences in results are discussed.
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008094:Lithium / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009048:Motor Skills / Q000187:drug effects; D010869:Pindolol / Q000627:therapeutic use*; D010919:Placebos; D014202:Tremor / Q000139:chemically induced / Q000188:drug therapy* / Q000523:psychology
D010919:Placebos; D008094:Lithium; D010869:Pindolol
Die Behandlung des Lithiumtremors mit dem Beta-Rezeptorenblocker Pindolol.