title: Inhibitory and mutagenic effects of sodium nitroprusside and its adenine complex on Escherichia coli.
abstract: Sodium nitroprusside and its adenine complex were found to decrease the growth rate of exponentially growing Escherichia coli cultures, and the adenine complex to exert in addition a bactericidal effect. In mutation experiments the latter compound failed to induce base-pair substitutions in the E. coli strains tested but the results do not allow to exclude other mutagenic mechanisms.
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics; D005292:Ferricyanides / Q000494:pharmacology*; D009153:Mutagens; D009154:Mutation; D009599:Nitroprusside / Q000031:analogs & derivatives / Q000494:pharmacology*; D014529:Uridine / Q000494:pharmacology
chemical_list: D005292:Ferricyanides; D009153:Mutagens; D009599:Nitroprusside; D000225:Adenine; D014529:Uridine