title: Radiocarbon (14C) migration and metabolism kinetics (a review).
abstract: Radiocarbon (14C) introduced into the biosphere as a result of nuclear explosions and operation of nuclear power stations has upset the equilibrium existing in nature. The increase in 14C concentration in the biosphere is a problem of considerable hygienic and social importance, since 14C affects all living organism in the world. This paper presents data on 14C migration and metabolism kinetics. Radiocarbon metabolism kinetics depends on the form of the chemical compound metabolized. Inorganic 14C compounds are metabolized relatively fast. Organic 14C compounds (carbohydrates, fats and proteins) are retained longer in the body. Differences in the metabolism kinetics of differents 14C compounds lead to the formation of unequal irradiation doses in various organs and tissues. In establishing standards for admissible 14C intake, one should take into consideration the kind of chemical compound in which the element is incorporated.
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D001853:Bone Marrow / Q000378:metabolism; D001842:Bone and Bones / Q000378:metabolism; D002250:Carbon Radioisotopes / Q000008:administration & dosage* / Q000032:analysis; D004040:Dietary Carbohydrates / Q000378:metabolism; D004041:Dietary Fats / Q000378:metabolism; D004044:Dietary Proteins / Q000378:metabolism; D006207:Half-Life; D006801:Humans; D007700:Kinetics; D010084:Oxidation-Reduction; D012995:Solubility
chemical_list: D002250:Carbon Radioisotopes; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins