[Hypothermic storage under aerobic conditions--the effect of different flushing solutions on kidney functional recovery].
Canine kidneys (n = 17) were flushed with COLLINS (C2), SACKS II, LAMBOTTE (KMgS), ROSS (hypertonic citrate), or RINGER glucose-mannitol solution following a 30-min period of normothermic ischemia. After 24 h hypothermic preservation with retrograde oxygen persufflation (ROP) and autotransplantation, the immediate functional recovery was determined using inulin and PAH clearance methods and compared with the normal contralateral kidney. While a good functional recovery was found in the COLLINS group, significantly exceeding results from hypothermic ischemic storage preservation, in experiments using other flush solutions ROP preservation resulted in only a small immediate function. Thus the experiments indicate that COLLINS solution C2 is the optimal flush solution for ROP preservation.
D000332:Aerobiosis; D000818:Animals; D004285:Dogs; D005069:Evaluation Studies as Topic; D007668:Kidney / Q000502:physiology; D016030:Kidney Transplantation; D010477:Perfusion / Q000379:methods; D012996:Solutions; D014021:Tissue Preservation / Q000379:methods*; D014182:Transplantation, Autologous
D012996:Solutions
Hypotherme Lagerung unter aeroben Bedingungen--Einfluss unterschiedlicher Freispüllösungen auf die Funktionserhaltung der Niere.