Attempt at enzyme replacement by organ transplantation: renal transplantation in Gaucher disease.
Following renal transplantation, hepatic glucocerebroside deposits in a child with Gaucher disease were reduced. This suggests that enzyme replacement had been achieved.
D002102:Cadaver; D002648:Child; D005260:Female; D005776:Gaucher Disease / Q000201:enzymology / Q000601:surgery*; D005959:Glucosidases / Q000378:metabolism*; D005962:Glucosylceramidase / Q000378:metabolism*; D005963:Glucosylceramides / Q000378:metabolism; D006801:Humans; D016030:Kidney Transplantation; D008099:Liver / Q000378:metabolism; D008297:Male; D014184:Transplantation, Homologous
D005963:Glucosylceramides; D005959:Glucosidases; D005962:Glucosylceramidase