title: [Endocrine and exocrine functional disorders in pancreatic diabetes].
abstract: In diabetic diseases of pancreatic origin we find three typical patterns of insulin secretion. The different insulin secretion allows a clear distinction of a diabetes of the maturity onset type and of the juvenile onset type type on the one hand and of a diabetes caused by a pancreatitis on the other hand. In a pancreatitis we see the expected reduction of the exocrine function. In the so called maturity onset diabetes a slight reduction of excretory functions could be seen. These results suggest that in maturity onset diabetes only a selective defect of the beta-cells exists, while in juvenile onset diabetes a destruction or reduction of beta-cells but an intact excretory function may be assumed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001639:Bicarbonates / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000209:etiology / Q000503:physiopathology*; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology; D005260:Female; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000473:pathology; D008049:Lipase / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000150:complications*; D010447:Peptide Hydrolases / Q000378:metabolism
chemical_list: D001639:Bicarbonates; D001786:Blood Glucose; D007328:Insulin; D008049:Lipase; D010447:Peptide Hydrolases
vernacular_title: Endokrine und exokrine Funktionsstörungen beim Pankreasdiabetes.