title: Orthopaedic problems of renal transplantation.
abstract: One in six patients receiving renal transplants has orthopaedic problems. Osteoporosis with accompanying fractures is common, as is avascular necrosis of the hips, knees, and other bones. Immunosuppressive therapy with steroids is implicated and its mode of action discussed. No means of prophylasix is known. If treated conservatively, aseptic necrosis of bone is much more disabling than is commonly believed as judged by the critical assessment technique of Charnley. The authors therefore recommend that a surgical approach should be adopted whenever possible.
mesh_terms: D000328:Adult; D002102:Cadaver; D004185:Disability Evaluation; D005260:Female; D005265:Femoral Neck Fractures / Q000209:etiology; D005271:Femur Head Necrosis / Q000209:etiology; D006801:Humans; D006811:Humerus; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016030:Kidney Transplantation; D008297:Male; D008684:Metatarsus; D008875:Middle Aged; D010020:Osteonecrosis / Q000209:etiology*; D010024:Osteoporosis / Q000209:etiology*; D011183:Postoperative Complications; D014184:Transplantation, Homologous
chemical_list: D007166:Immunosuppressive Agents