title: The role of radiosensitizing drugs in the management of cancer.
abstract: This paper discusses the role of radiosensitizers not only as adjuncts in the radiotherapy of local neoplastic disease but also in the potential management of metastases by virtue of their direct cytotoxic effects upon hypoxic cells.
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D006224:Cricetinae; D006801:Humans; D006931:Hyperbaric Oxygenation; D008795:Metronidazole / Q000494:pharmacology; D051379:Mice; D008920:Misonidazole / Q000494:pharmacology; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000532:radiotherapy; D009502:Neutrons; D011836:Radiation Tolerance; D011838:Radiation-Sensitizing Agents / Q000627:therapeutic use*; D011878:Radiotherapy / Q000379:methods; D051381:Rats
chemical_list: D011838:Radiation-Sensitizing Agents; D008795:Metronidazole; D008920:Misonidazole