title: Methotrexate and central nervous system toxicity.
mesh_terms: D001708:Biopterins / Q000031:analogs & derivatives / Q000378:metabolism; D001921:Brain / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects; D002648:Child; D006801:Humans; D007945:Leukemia, Lymphoid / Q000628:therapy; D008727:Methotrexate / Q000009:adverse effects*; D011832:Radiation Injuries
chemical_list: D001708:Biopterins; D008727:Methotrexate