title: [Biological effects of distamycin A].
abstract: In the present review are examined different biological effects of Distamycin A, an antibiotic produced by Streptomyces distallicus. This drug is moderately active on bacteria but it is strongly active on DNA viruses and on some Oncornaviruses, moreover it possesses antineoplastic and antimitotic activity at high doses at which it can result tossic and cause immunodepression.
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D002472:Cell Transformation, Viral / Q000187:drug effects; D004214:Distamycins / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D009374:Neoplasms, Experimental / Q000188:drug therapy; D011758:Pyrroles / Q000494:pharmacology*; D014780:Viruses / Q000187:drug effects*
chemical_list: D004214:Distamycins; D011758:Pyrroles
vernacular_title: Effetti biologici dell distamicina A.