title: ["In vitro" and "in vivo" antibacterial activity of a new synthetic antibiotic cinoxacin].
abstract: The Authors have conducted the experimental studies tending to valuate the antibacterial activity in vitro and in vivo of cinoxacin versus that demonstrated by nalidixic acid. The obtained results demonstrate the cinoxacin presents a similar antibacterial activity to that of nalidixic acid.
mesh_terms: D000818:Animals; D001407:Bacillus / Q000187:drug effects; D001419:Bacteria / Q000187:drug effects*; D002937:Cinoxacin / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D007709:Klebsiella / Q000187:drug effects; D051379:Mice; D008826:Microbial Sensitivity Tests; D011511:Proteus / Q000187:drug effects; D011724:Pyridazines / Q000494:pharmacology*; D012475:Salmonella / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013291:Streptococcus / Q000187:drug effects
chemical_list: D011724:Pyridazines; D002937:Cinoxacin
vernacular_title: Attivita antibatterica "in vitro" e "in vivo" di un nuovo antibiotico sinetetico: il cinoxacin.