title: Cyclic release of luteinizing hormone and the effects of luteinizing hormone-releasing hormone injection in Asiatic elephants.
abstract: Cyclic changes in serum concentration of luteinizing hormone (LH) were observed throughout the estrous cycle of Asiatic elephants (Elephas maximus). The increase in serum LH was correlated with a slight increase in serum estradiol concentration and the onset of behavioral heat (willingness to mate). In a second series of studies, injection of luteinizing hormone-releasing hormone after 3 days of estrone administration induced an increase in serum LH. These studies indicate that the Asiatic elephant exhibits a cyclic LH release that can be experimentally induced by estrone and luteinizing hormone-releasing hormone administration.
mesh_terms: D000818:Animals; D004606:Elephants / Q000502:physiology*; D004967:Estrogens / Q000097:blood; D004970:Estrone / Q000494:pharmacology; D004971:Estrus; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D007986:Luteinizing Hormone / Q000097:blood*; D011247:Pregnancy
chemical_list: D004967:Estrogens; D004970:Estrone; D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone