Maintenance of mydriasis with topical indomethacin during and after penetrating keratoplasty in the rabbit.
The use of indomethacin eyedrops, 0.5%, in combination with topical atropine and phenylephrine, prior to and immediately following an 8-mm penetrating keratoplasty in rabbits maintains maximal pupillary dilation. With this technique, we achieved clear grafts without synechiae in virtually every instance.
D000287:Administration, Topical; D000818:Animals; D001285:Atropine / Q000008:administration & dosage; D016039:Corneal Transplantation; D005260:Female; D007213:Indomethacin / Q000008:administration & dosage*; D008297:Male; D009184:Mydriatics; D009883:Ophthalmic Solutions; D010656:Phenylephrine / Q000008:administration & dosage; D011182:Postoperative Care; D011680:Pupil / Q000187:drug effects*; D011817:Rabbits; D014184:Transplantation, Homologous
D009184:Mydriatics; D009883:Ophthalmic Solutions; D010656:Phenylephrine; D001285:Atropine; D007213:Indomethacin