A double-blind crossover comparison of topical anesthetics.
Three topical anesthetics and a placebo were compared in 102 separate trials. The degree of anesthesia produced with each agent was determined by placing a needle in the palate near the palatal foramen. Pain produced was rated by the participants on a scale from 1 to 5.
D000287:Administration, Topical; D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage*; D001566:Benzocaine / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage; D008297:Male; D010146:Pain / Q000517:prevention & control; D010919:Placebos; D013748:Tetracaine / Q000008:administration & dosage
D000779:Anesthetics, Local; D010919:Placebos; D013748:Tetracaine; D008012:Lidocaine; D001566:Benzocaine