LH-RH and HCG studies in a Turner phenotype male (Noonan's syndrome). A case report.
LH-RH and HCG stimulation tests were performed in a prepubertal 13-year-old boy with Noonan's syndrome. The basal plasma LH (0.8 mIU/ml) was normal and FSH (2.5 mIU/ml) high, with an elevated response of both LH (8.3 mIU/ml) and FSH (9.6 mIU/ml) to LH-RH, as seen in primary hypogonadism. However, the patient had a normal testosterone response to HCG (437 ng%). These conflicting test results illustrate the difficulty of predicting potential for fertility in patients with Turner phenotype male.
D000293:Adolescent; D006063:Chorionic Gonadotropin; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009634:Noonan Syndrome / Q000097:blood*; D013739:Testosterone / Q000097:blood
D006063:Chorionic Gonadotropin; D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone