Relationship between deoxyribonucleoside triphosphate pools and deoxyribonucleic acid synthesis in an nrdA mutant of Escherichia coli.
A shift to 42 degrees C in an nrdA mutant causes a decrease in deoxyribonucleic acid synthesis without a concomitant decrease in deoxynucleotide triphosphate pools.
D004261:DNA Replication; D004269:DNA, Bacterial / Q000096:biosynthesis*; D003854:Deoxyribonucleotides / Q000378:metabolism*; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D012262:Ribonucleoside Diphosphate Reductase / Q000378:metabolism; D013696:Temperature
D004269:DNA, Bacterial; D003854:Deoxyribonucleotides; D012262:Ribonucleoside Diphosphate Reductase