In vitro lymphocytes stimulation with scarlet fever toxin.
Rabbit peripheral blood, spleen and thymus lymphocytes were stimulated in vitro with scarlet fever toxin. The ultrastructure of stimulated blast cells was described; the morphological features of these cells are similar to those of T-lymphoblasts. 3H-thymidine incorporation into lymphocytes stimulated with ET or PHA was studied in correlation with blast formation. Some quantitative discrepancies between both parameters are discussed.
D000818:Animals; D001427:Bacterial Toxins / Q000494:pharmacology*; D008213:Lymphocyte Activation / Q000187:drug effects*; D008214:Lymphocytes / Q000378:metabolism / Q000648:ultrastructure; D010835:Phytohemagglutinins / Q000494:pharmacology; D011817:Rabbits; D012541:Scarlet Fever; D013297:Streptococcus pyogenes; D013936:Thymidine / Q000378:metabolism
D001427:Bacterial Toxins; D010835:Phytohemagglutinins; D013936:Thymidine