title: Complex surveillance of Streptococcus pyogenes. IV. The phenomenon of interference of human serum under the conditions of the bactericidal test.
abstract: The phenomenon of interference of human sera under the conditions of the bactericidal test was described. In the presence of these sera, secondarily non-resistant strains of Streptococcus pyogenes were capable of vigorous growth and anti M 12 bactericidal activity was impaired. The factor was found in the albumin fraction and has probably the character of a blocking cytophilic lymphokin. It can markedly distort the interpretation of the bactericidal test.
mesh_terms: D000328:Adult; D001769:Blood / Q000382:microbiology; D001770:Blood Bactericidal Activity; D002464:Cell Migration Inhibition; D005260:Female; D006801:Humans; D010612:Pharyngitis / Q000276:immunology*; D012709:Serum Albumin / Q000276:immunology; D013290:Streptococcal Infections / Q000276:immunology*; D013297:Streptococcus pyogenes / Q000254:growth & development / Q000276:immunology*
chemical_list: D012709:Serum Albumin