[Antigenic activity and the reactogenicity of UV ray-inactivated antirabies vaccine from the brain of sheep].
Tests in volunteers showed that the reactogenicity of rabies vaccine prepared from sheep brain and inactivated with ultraviolet rays was not greater than the reactogenicity of Fermi vaccine. At the same time it was found to have a higher activity when injected both in the form of 5% suspension (in full and decreased doses) and with brain tissue content as low as 2.5%.
D000293:Adolescent; D000328:Adult; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000276:immunology*; D001733:Bites and Stings / Q000188:drug therapy; D001921:Brain / Q000276:immunology*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D006801:Humans; D007114:Immunization; D008875:Middle Aged; D011818:Rabies / Q000517:prevention & control; D011819:Rabies Vaccines / Q000276:immunology / Q000528:radiation effects*; D011820:Rabies virus / Q000276:immunology; D012756:Sheep / Q000276:immunology; D013997:Time Factors; D014466:Ultraviolet Rays; D014613:Vaccines, Attenuated / Q000276:immunology / Q000528:radiation effects*
D000914:Antibodies, Viral; D000956:Antigens, Viral; D011819:Rabies Vaccines; D014613:Vaccines, Attenuated
Antigennaia aktivnost' i reaktogennost' inaktivirovannoĭ UF-luchami antirabicheskoi vaktsiny iz mozga ovets.