[Maintenance of the circulation and the restoration of heart function in the donor body by means of direct mechanical heart massage for subsequent transplantation (an experimental study)].
The possibility of maintenance of circulation and subsequent restoration of the function of the heart in the organism of the donor, after 10-minute arrest of circulation, for transplantation of the heart was investigated. Study of the hemodynamic, biochemical, metabolic, and structural changes in the myocardium after 2-hour mechanical massage without and with pharmacological protection of the myocardium (glucose--insulin--potassium, hydrocortisone, dipyridamole), without and with restoration of cardiac activity in the organism of the donor and the recipient after transplantation of the second heart by the method suggested by Moory et al. in artificially created left ventricular insufficiency showed that direct mechanical massage of the heart may be used for its short-term preservation in the donor organism.
D000818:Animals; D001775:Blood Circulation; D003326:Coronary Circulation; D004285:Dogs; D006321:Heart / Q000502:physiology; D006336:Heart Massage / Q000379:methods*; D016027:Heart Transplantation; D006439:Hemodynamics; D006706:Homeostasis; D013997:Time Factors; D014019:Tissue Donors
Podderzhanie tsirkuliatsii i vosstanovlenie funktsii serdtsa v organizme donora s pomoshch'iu priamogo mekhanicheskogo kardiomassazha dlia posleduiushcheĭ transplantatsii (éksperimental'noe issledovanie).