title: Papular acrodermatitis of childhood and other papulo-vesicular acro-located syndromes.
abstract: Papular acrodermatitis of childhood (PAC), first recognized in Milan and described by Gianotti in 1955, is an infectious disease of childhood, of low infectivity, fairly widespread, and characterized by: (1) Non-relapsing erythemato-papular dermatitis localized to the face and limbs, lasting about 3 weeks. (2) Paracortical hyperplasia of lymph-nodes. (3) Acute hepatitis, usually anicteric, which lasts at least 2 months and may progress to chronic liver disease.
mesh_terms: D000169:Acrodermatitis / Q000150:complications / Q000276:immunology / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D006505:Hepatitis / Q000150:complications / Q000276:immunology / Q000473:pathology; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D006965:Hyperplasia; D008198:Lymph Nodes / Q000473:pathology; D012867:Skin / Q000473:pathology; D013577:Syndrome
chemical_list: D006514:Hepatitis B Surface Antigens