Contraception via topical application? - A review.
The skin, generally speaking, is not an absorption organ but one of its major functions is the protection of the body against the entrance of foreign material. Under certain circumstances, however, drugs can be introduced into the skin and thereby into the body as can be seen in the topical treatment of skin diseases. Though percutaneous pharmacokinetics of steroids seem appropriate for contraception, the variability of the absorption process appears to be too high for this purpose.
D000042:Absorption; D000287:Administration, Topical; D001790:Blood Physiological Phenomena; D003267:Contraception; D004817:Epidermis / Q000187:drug effects; D006801:Humans; D008208:Lymphatic System / Q000502:physiology; D012679:Sense Organs / Q000502:physiology; D012867:Skin / Q000187:drug effects*; D012869:Skin Absorption / Q000187:drug effects; D013997:Time Factors