Restoration of DNA synthesis at non-permissive temperature and of UV resistance induced by bacteriophage Mu in Escherichia coli lig ts7 strain.
Infected by Mu, a mutant of E. coli, carrying the mutation lig ts7 shows a UV sensitivity intermediate between that of the uninfected lig-strain and that of the parental lig+ strain. At non-permissive temperature bacterial DNA replication is restored upon infection. These results suggest that DNA-ligase activity is coded for by the phage Mu genome.
D003090:Coliphages / Q000502:physiology*; D011088:DNA Ligases / Q000235:genetics; D004269:DNA, Bacterial / Q000096:biosynthesis*; D004926:Escherichia coli / Q000378:metabolism / Q000502:physiology* / Q000528:radiation effects; D007700:Kinetics; D009154:Mutation; D013696:Temperature; D014466:Ultraviolet Rays
D004269:DNA, Bacterial; D011088:DNA Ligases