The mutagenic effect of benzene, toluene and xylene studied by the SCE technique.
In experiments in vitro, neither benzene, toluene nor xylene changed the number of sister-chromatid exchanges (SCEs) or the number of chromosomal aberrations in human lymphocytes. Toluene and xylene caused a significant cell growth inhibition which was not observed with benzene in the same concentrations.
D001554:Benzene / Q000494:pharmacology*; D003434:Crossing Over, Genetic; D004305:Dose-Response Relationship, Drug; D005821:Genetic Techniques; D006801:Humans; D009153:Mutagens; D014050:Toluene / Q000494:pharmacology*; D014992:Xylenes / Q000494:pharmacology*
D009153:Mutagens; D014992:Xylenes; D014050:Toluene; D001554:Benzene