title: [Antitumor action of preparation No. 31 in malignant tumors of the ovaries (a clinical cytological study)].
abstract: The authors have analysed clinico-cytological findings to estimate the efficacy of the preparation No 31 therapy in 18 primary patients with ascites forms of malignant epithelial tumors of the ovary. This preparation was found to be a highly effective chemotherapeutic agent possessing a marked cytolytic effect on tumor cells. The method of cytological assay of the serous cavities exudates may be utilized to determine the tumor sensitivity to the agent under test at early terms of the treatment, while being correlated with clinical data the former may be used to estimate the effectiveness of the chemotherapy.
mesh_terms: D000328:Adult; D000368:Aged; D000477:Alkylating Agents; D000970:Antineoplastic Agents; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000473:pathology; D014227:Triazines / Q000627:therapeutic use*
chemical_list: D000477:Alkylating Agents; D000970:Antineoplastic Agents; D014227:Triazines
vernacular_title: Protivoopukholevoe deistvie preparata No. 31 pri zlokachestvennykh opukholiakh iaichnikov (kliniko-tsitologicheskoe izuchenie).