Dynamic study of the blood viscosity of insulin-dependent diabetics by means of an artificial pancreas.
The blood viscosity of 15 insulin-dependent, poorly controlled, diabetic subjects was determined by using a microviscosimeter at low shear rates, with cylindrical cuvettes of the Couette type. It was found that the blood viscosity of these diabetics was more elevated than that of control patients (p less than 0.001). In ten diabetics, the return to a strict metabolic control over a period of more than 24 h by means of an artificial pancreas resulted in a significant systematic lowering of blood viscosity. These results suggest that the metabolic control of diabetes influences blood viscosity, and they underline the importance of an artificial pancreas for the dynamic study of the factors affecting blood viscosity during the course of diabetes.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001187:Artificial Organs; D001786:Blood Glucose / Q000378:metabolism; D001809:Blood Viscosity; D003201:Computers; D003920:Diabetes Mellitus / Q000097:blood / Q000188:drug therapy*; D005246:Feedback; D005260:Female; D006801:Humans; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use*; D007515:Islets of Langerhans / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic
D001786:Blood Glucose; D007328:Insulin