[Immunocytochemistry of pancreatic and pancreatico-duodenal apudomas].
Immunocytochemical techniques, applied to material fixed with Bouin's fluid and using immune sera specific to various hormonal polypeptide(s), give a classification of pancreatic and pancreatico-duodenal apudomas based upon cellular functional activity. With a rane containing a minimum of five antibodies (gastrin, insulin, glucagon, somatostatin and pancreatic polypeptide), 15 tumours could be identified amongst the 22 tested. They were either "monohormonal" tumours (10 cases) or "bi- or polyhormonal" tumours (5 cases). In the remaining 7 cases, only rare cells were immunoreactive. A large number of immunoreactivities thus revealed in histological sections are clinically silent or are present in a "forme fruste".
D000818:Animals; D001079:Apudoma / Q000032:analysis* / Q000145:classification / Q000473:pathology; D002417:Cattle; D004379:Duodenal Neoplasms / Q000032:analysis* / Q000145:classification / Q000473:pathology; D005455:Fluorescent Antibody Technique; D006168:Guinea Pigs; D006651:Histocytochemistry; D006801:Humans; D010190:Pancreatic Neoplasms / Q000032:analysis* / Q000145:classification / Q000473:pathology; D011817:Rabbits
Immunocytochimie des apudomes pancréatiques et pancréatico-duodénaux.