Antibodies to phospholipids in experimental nocardiosis.
Live Nocardia asteroides injected intraperitoneally into guinea pigs produced antibodies to phospholipids of Nocardia whereas antibodies were not detected in animals injected with heat-killed N. asteroides. The antibody titer was found to be related with the degree of infection; a significant decrease was noted after sulfadiazine treatment suggesting that antibodies were produced in response to an increasing bacterial load that occurred as the infection progressed.
D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D006168:Guinea Pigs; D006358:Hot Temperature; D009617:Nocardia Infections / Q000188:drug therapy / Q000276:immunology*; D009616:Nocardia asteroides / Q000276:immunology*; D010743:Phospholipids / Q000276:immunology*; D013411:Sulfadiazine / Q000627:therapeutic use
D000907:Antibodies, Bacterial; D010743:Phospholipids; D013411:Sulfadiazine