Complex surveillance of Streptococcus pyogenes. IV. The phenomenon of interference of human serum under the conditions of the bactericidal test.
The phenomenon of interference of human sera under the conditions of the bactericidal test was described. In the presence of these sera, secondarily non-resistant strains of Streptococcus pyogenes were capable of vigorous growth and anti M 12 bactericidal activity was impaired. The factor was found in the albumin fraction and has probably the character of a blocking cytophilic lymphokin. It can markedly distort the interpretation of the bactericidal test.
D000328:Adult; D001769:Blood / Q000382:microbiology; D001770:Blood Bactericidal Activity; D002464:Cell Migration Inhibition; D005260:Female; D006801:Humans; D010612:Pharyngitis / Q000276:immunology*; D012709:Serum Albumin / Q000276:immunology; D013290:Streptococcal Infections / Q000276:immunology*; D013297:Streptococcus pyogenes / Q000254:growth & development / Q000276:immunology*
D012709:Serum Albumin