Effect of drugs on intrauterine growth.
Although the teratogenic potential of maternally administered drugs is well known, their stimulation of intrauterine growth retardation may be equally deleterious. Possible adverse effects of propranolol, steroids, anticonvulsants, tranquilizers, and maternal smoking and drinking are discussed. Questions of fetal development and maternal management are considered in light of their interference with the mechanism of growth regulation.
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000818:Animals; D000431:Ethanol / Q000009:adverse effects; D005260:Female; D005317:Fetal Growth Retardation / Q000139:chemically induced* / Q000209:etiology; D005333:Fetus / Q000187:drug effects* / Q000502:physiology; D006128:Growth / Q000187:drug effects; D006801:Humans; D007743:Labor, Obstetric / Q000187:drug effects; D008431:Maternal-Fetal Exchange; D010634:Phenobarbital / Q000009:adverse effects; D011241:Prednisone / Q000009:adverse effects; D011247:Pregnancy; D011433:Propranolol / Q000009:adverse effects; D012907:Smoking / Q000150:complications; D013997:Time Factors
D000431:Ethanol; D011433:Propranolol; D011241:Prednisone; D010634:Phenobarbital