title: Metabolic changes in pregnancy relevant to diabetes mellitus.
abstract: The alterations in carbohydrate metabolism during pregnancy are discussed and possible mechanisms for these changes are put forward. It is stressed that the raised levels of plasma glucose, the enhanced response to insulin and the decreased tissue sensitivity to insulin are all features of normal pregnancy. It may be difficult to distinguish this from very early forms of diabetes mellitus during pregnancy, the detection of which is briefly considered.
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D050260:Carbohydrate Metabolism; D005260:Female; D005934:Glucagon / Q000097:blood; D005951:Glucose Tolerance Test; D006441:Hemoglobin A / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000096:biosynthesis / Q000097:blood; D007333:Insulin Resistance; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000175:diagnosis* / Q000378:metabolism; D011384:Proinsulin / Q000096:biosynthesis
chemical_list: D001786:Blood Glucose; D007328:Insulin; D005934:Glucagon; D006441:Hemoglobin A; D011384:Proinsulin