Double blind trial of ritodrine and placebo in twin pregnancy.
In a double blind trial, 25 patients with twin pregnancy were given 40 mg of ritodrine hydrochloride by mouth daily and 24 similar patients received a placebo. The ritodrine group had no significant prolongation of pregnancy nor increase in birth weight, and a high incidence of side effects occurred.
D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005317:Fetal Growth Retardation / Q000517:prevention & control; D006801:Humans; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000517:prevention & control*; D010919:Placebos; D011247:Pregnancy; D011272:Pregnancy, Multiple; D011412:Propanolamines / Q000627:therapeutic use*; D012312:Ritodrine / Q000009:adverse effects / Q000627:therapeutic use*; D014427:Twins
D010919:Placebos; D011412:Propanolamines; D012312:Ritodrine