title: Prostaglandin I2 partially inhibits human platelet aggregation stimulated by antithymocyte globulin.
abstract: Antithymocyte globulin (ATG), which is used as an immunosuppressive agent in organ transplantation, has the side effect of inducing platelet aggregation. The present in vitro studies show that a component of ATG induced platelet aggregation can be inhibited by prostaglandin I2.
mesh_terms: D000961:Antilymphocyte Serum / Q000494:pharmacology*; D001792:Blood Platelets / Q000502:physiology*; D011464:Epoprostenol / Q000494:pharmacology*; D006801:Humans; D011453:Prostaglandins / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000961:Antilymphocyte Serum; D011453:Prostaglandins; D011464:Epoprostenol