title: Nucleolar DNA organization in the interphase nuclei of mouse fibroblasts.
abstract: The organization of nucleolar DNA in interphase nuclei of somatic cells was studied at the ultrastructural level using oxidized DAB as a nucleic acid stain. Some finely filamentous networks of DNA-containing structures were observed within the nucleolar fibrillar component. They originated from the perinucleolar shell of condensed chromatin and from a chromatinic area with a honeycomb like structure. The latter was significantly associated with nucleoli and is believed to be a part of the nucleolar organizer region.
mesh_terms: D015100:3,3'-Diaminobenzidine; D000818:Animals; D002466:Cell Nucleolus / Q000648:ultrastructure*; D004247:DNA / Q000378:metabolism*; D003851:Deoxyribonucleases / Q000378:metabolism; D006652:Histological Techniques; D007739:L Cells; D051379:Mice; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D012260:Ribonucleases / Q000378:metabolism
chemical_list: D015100:3,3'-Diaminobenzidine; D004247:DNA; D003851:Deoxyribonucleases; D012260:Ribonucleases