Demonstration of lactoferrin in tumor tissue from two patients with positive gallium scans.
We have detected lactoferrin in tumor tissue from a patient with Hodgkin's disease and a patient with Burkitt's lymphoma. Both patients had radiogallium scans demonstrating increased uptake in the tumor tissue subsequently found to contain lactoferrin. Tissue assay for lactoferrin was performed by the indirect immunofluorescence method. Control splenic tissue showed either slight lactoferrin content or none.
D000328:Adult; D002051:Burkitt Lymphoma / Q000032:analysis / Q000000981:diagnostic imaging*; D002648:Child; D005455:Fluorescent Antibody Technique; D005710:Gallium Radioisotopes; D006689:Hodgkin Disease / Q000032:analysis / Q000000981:diagnostic imaging*; D006801:Humans; D007781:Lactoferrin / Q000032:analysis* / Q000276:immunology; D007782:Lactoglobulins / Q000032:analysis*; D008297:Male; D011877:Radionuclide Imaging; D013154:Spleen / Q000032:analysis
D005710:Gallium Radioisotopes; D007782:Lactoglobulins; D007781:Lactoferrin