title: [Functional interactions of the genomes of Shigella sonnei phages and Escherichia coli phage T4 in mixed infection].
abstract: A comparative study of Shigella sonnei phages U and G and Escherichia coli phage T4 has shown that enzymes coded for by the Sh. sonnei phages can functionally substitute for some T4-coded products. This finding in indicative of an evolutionary relationship between T-even phages and disenteric phages U and G. The U phage is uncapable to compensate amber mutants for the genes that control the conversion of cytosine into 5-hydroxymethyl cytosine (5-HMC) and the glucosylation of the latter, which agrees with our earlier finding that the U phage DNA contains no 5-HMC. U and G phages are also found to exclude the T4 phage in the course of mixed infection.
mesh_terms: D001435:Bacteriophages / Q000235:genetics*; D003596:Cytosine / Q000031:analogs & derivatives / Q000378:metabolism; D004279:DNA, Viral / Q000235:genetics; D005814:Genes, Viral / Q000528:radiation effects; D005815:Genetic Code; D066298:In Vitro Techniques; D009154:Mutation; D012764:Shigella sonnei / Q000235:genetics*; D013604:T-Phages / Q000235:genetics*; D014466:Ultraviolet Rays; D014776:Virus Cultivation
chemical_list: D004279:DNA, Viral; D003596:Cytosine
vernacular_title: Funktsional'nye vzaimodeĭstviia genomov fagov Shigella sonnei i faga Escherichia coli T4 pri smeshannoĭ infektsii.