title: Cholelithiasis. Review of advances in research.
abstract: Cholelithiasis is now known to result from multiple causes and to have distinct clinical correlates. New knowledge about its pathophysiology and relationship to altered hepatic metabolism, the enterohepatic circulation, and gallbladder function has led to theories of prevention and to medical methods of treatment, including dissolution of stones by bile acid therapy.
mesh_terms: D000328:Adult; D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism; D001663:Bilirubin; D002769:Cholelithiasis / Q000175:diagnosis / Q000378:metabolism* / Q000628:therapy; D002784:Cholesterol / Q000378:metabolism; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D006903:Hydroxymethylglutaryl CoA Reductases / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D011247:Pregnancy
chemical_list: D001647:Bile Acids and Salts; D002784:Cholesterol; D006903:Hydroxymethylglutaryl CoA Reductases; D001663:Bilirubin