[Bactericidal action of formalin on the causative agent of plague].
Ten per cent neutral formalin in a ratio 1 : 20 was demonstrated to be useful as a desinfecting and fixing substance in pathohistological examinations of organs and tissues animals infected with the causative agent of plague. With test-objects' volume of 1.0 cm3 the optimal period of exposure providing a permanent bactericidal effect is 24 hours, with volumes of 1.5 and 2.0 cm3-2 days. The fixing effect of formalin on tissues is exerted in 3-4 days.
D000818:Animals; D004202:Disinfectants; D004305:Dose-Response Relationship, Drug; D005557:Formaldehyde / Q000494:pharmacology*; D006168:Guinea Pigs; D006652:Histological Techniques; D051379:Mice; D010930:Plague / Q000382:microbiology; D012996:Solutions; D013997:Time Factors; D015010:Yersinia pestis / Q000187:drug effects*
D004202:Disinfectants; D012996:Solutions; D005557:Formaldehyde
Izuchenie bakteritsidnogo deĭstviia formalina na vozbuditelia chumy.