title: Electroencephalographic and clinical changes as correlated in geriatric patients treated three months with an ergot alkaloid preparation.
abstract: The results of a 3-month trial with an ergot alkaloid preparation (Hydergine) in 16 geriatric patients showed that, in accordance with a previously proposed working hypothesis, the improvement induced by the drug in electroencephalographic age-related changes was accompanied by clinical improvement in patients with similarly age-related mental deterioration.
mesh_terms: D000342:Affective Symptoms / Q000188:drug therapy; D000368:Aged; D000513:Alpha Rhythm; D001007:Anxiety / Q000188:drug therapy; D001143:Arousal / Q000187:drug effects; D002986:Clinical Trials as Topic; D003704:Dementia / Q000188:drug therapy*; D003863:Depression / Q000188:drug therapy; D004088:Dihydroergotoxine / Q000627:therapeutic use*; D004311:Double-Blind Method; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D004088:Dihydroergotoxine