Corneal ulceration secondary to intestinal Shigella sonnei.
A 34-month-old boy had a corneal ulcer due to Shigella sonnei. To my knowledge, this is the first documented case reported where the same organism was recovered from the stool. One other case of S sonnei and two cases of S flexneri corneal ulcers have appeared in the literature. All cases have been in young black boys between the ages of 23 months and 6 years. The exact pathogenesis remains unclear, but direct fecalocular inoculation into a preexisting epithelial defect, a probable herpetic dendrite in this case, is most likely.
D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003320:Corneal Ulcer / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D003646:Debridement; D003937:Diagnosis, Differential; D004405:Dysentery, Bacillary / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007223:Infant; D007635:Keratitis, Dendritic / Q000175:diagnosis; D008297:Male; D010403:Penicillin Resistance; D012764:Shigella sonnei / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D000667:Ampicillin