title: Necrotizing infection of scrotum.
abstract: Necrotizing infection of the scrotum (Fournier gangrene) rapidly spreads to adjacent skin with fever and toxemia and is life-threatening. Subcutaneous gas and a foul-smelling wet discharge from the skin are usually present. The infection is not cured with antibiotic therapy alone and requires immediate extensive debridement of all necrotic tissue. Repeated debridement each several days under general anesthesia is necessary until healthy granulation is present in the wound. Reconstruction with skin flaps or skin grafts shortens hospitalization and prevents the dense scar tissue and immobility of the tests that can occur with spontaneous epithelization.
mesh_terms: D000328:Adult; D000368:Aged; D001442:Bacteroides Infections / Q000628:therapy; D004756:Enterobacteriaceae Infections / Q000628:therapy; D004927:Escherichia coli Infections / Q000628:therapy; D005734:Gangrene / Q000628:therapy*; D005738:Gas Gangrene / Q000628:therapy; D005832:Genital Diseases, Male / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D012611:Scrotum; D013203:Staphylococcal Infections / Q000628:therapy; D013290:Streptococcal Infections / Q000628:therapy; D013577:Syndrome