title: [Stereotaxic ventroposteromedial thalamotomy in the treatment. Clinical observations and physiopathological considerations].
abstract: In 6 patients the authors performed stereotaxic ventroposteromedial thalamotomy for abolition or reduction of pain. The operation produced lesions in the centrum medianum and parasfascicular nucleus. In 2 cases unilateral operation was performed contralaterally to the side of pain, in the remaining cases the operation was done bilaterally as a one-step procedure. Postoperative follow demonstrated that in 1 case improvement was completely absent, in 4 initial good effect was transient and pain returned after several weeks and in only 1 patient very good effect persists for over 12 months. In the light of these experiences and a survey of the pertinent literature the authors reach the conclusion that limited stereotatic lesion of the so called non-specific pain-transmitting thalamic nuclei produces permanent abolition or alleviation of pain in few cases only. The pathophysiology of pain is discussed in the light of these data.
mesh_terms: D000328:Adult; D000368:Aged; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009619:Nociceptors / Q000503:physiopathology; D010146:Pain / Q000209:etiology / Q000503:physiopathology; D059408:Pain Management; D013238:Stereotaxic Techniques; D013788:Thalamus / Q000601:surgery*
vernacular_title: Stereotaktyczna talamotomia brzuszna tylno-przyśrodkowa w leczeniu bólu. Spostrzezenia kliniczne i rozwazania patofizjologiczne.