[The effect of an oral aminophylline compound with protracted activity on respiratory resistance and blood gases in obstructive respiratory diseases (author's transl)].
The effect of theophylline ethylenediamine oblong tablets (Euphyllin retard) was tested in 40 patients by means of a double-blind trial, applying a dose of 2 X 350 mg/d and 2 X 700 mg/d. At the dose of 2 X 700 mg/d Euphyllin retard showed a good bronchodilatory effect. A reduction of the obstruction in the airways and an improvement of the arterial blood gases was statistically secured. At the dose of 2 X 350 mg/d a sufficient bronchodilation could not be recorded.
D000328:Adult; D000368:Aged; D000403:Airway Resistance / Q000187:drug effects*; D000628:Aminophylline / Q000008:administration & dosage / Q000494:pharmacology*; D001158:Arteries; D002245:Carbon Dioxide / Q000097:blood*; D002986:Clinical Trials as Topic; D003692:Delayed-Action Preparations; D004311:Double-Blind Method; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000097:blood / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*
D003692:Delayed-Action Preparations; D002245:Carbon Dioxide; D000628:Aminophylline; D010100:Oxygen
Die Wirkung eines oralen Aminophyllin-Präparates mit Retardwirkung auf die Atemwegswiderstände und arteriellen Blutgase bei obstruktiven Atemwegserkrankungen.