Comparison of sulpiride and chlorpromazine in psychoses. A double-blind multicentre study.
In a material of 71 patients admitted because of acute or chronic psychoses, 32 were treated with sulpiride (up to 1,800 mg per day) and 39 with chlorpromazine (up to 675 mg). Duration of treatment was from 4 to 8 weeks. The effect of the two preparations was very similar as were the type and frequency of side effects, except that sulpiride did not cause sunrash.
D000328:Adult; D002746:Chlorpromazine / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004341:Drug Evaluation; D006801:Humans; D008875:Middle Aged; D010259:Paranoid Disorders / Q000188:drug therapy; D011618:Psychotic Disorders / Q000188:drug therapy*; D012559:Schizophrenia / Q000188:drug therapy; D013469:Sulpiride / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors
D013469:Sulpiride; D002746:Chlorpromazine