Recombinant plasmids formed in vivo carrying and expressing two incompatibility regions.
The formation in vivo of recombinants between a plasmid of incompatibility group N (R1010-10) and plasmids of groups P (R751) and W (R388) is described. From examination of the molecular weights of these recombinant plasmids, they appear to be cointegrates. These cointegrates have the incompatibility properties of both 'parent' plasmids.
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004269:DNA, Bacterial / Q000032:analysis*; D004270:DNA, Circular / Q000032:analysis*; D004274:DNA, Recombinant / Q000032:analysis*; D004926:Escherichia coli / Q000032:analysis / Q000187:drug effects / Q000235:genetics*; D005809:Genes, Regulator; D008970:Molecular Weight; D009690:Nucleic Acid Conformation; D011815:R Factors; D011995:Recombination, Genetic; D014295:Trimethoprim / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004270:DNA, Circular; D004274:DNA, Recombinant; D014295:Trimethoprim