Heterotopically induced bone marrow. The concentration of hemopoietic stem cells in the induced bone marrow and its ability to repopulate lethally irradiated recipients.
Bone marrow induced in mice by xenogeneic epithelia of human amnion established cell line and of dog transitional epithelium seems to contain hemopoietic stem cells in the same concentration as orthotopic bone marrow. The induced bone marrow is able to protect lethally irradiated syngeneic recipients when used in the same doses as orthotopic one.
D000650:Amnion / Q000166:cytology; D000818:Animals; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D002460:Cell Line; D003114:Colony-Forming Units Assay; D004285:Dogs; D004847:Epithelial Cells; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D051379:Mice; D011828:Radiation Chimera; D014183:Transplantation, Heterologous