title: [Effect of sodium oxybutyrate on reflex hemodynamic reactions].
abstract: Clinical examination of patients with diseases of the lungs and locomotor system during the surgical treatment and experiments in animals has shown that sodium hydroxybutyrate used as an anesthetizing drug under conditions of the neuroleptic analgesia fails to provide an effective defense against the surgical trauma. This is shown by the instability in the hemodynamic indices, metabolic shifts and the presence of nociceptive viscero-somatic reflexes.
mesh_terms: D000368:Aged; D000771:Anesthesia, Intravenous; D000818:Animals; D001842:Bone and Bones / Q000293:injuries; D002986:Clinical Trials as Topic; D004353:Drug Evaluation, Preclinical; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006885:Hydroxybutyrates / Q000494:pharmacology; D007596:Joints / Q000293:injuries; D008171:Lung Diseases / Q000601:surgery; D008875:Middle Aged; D011013:Pneumonectomy; D011229:Preanesthetic Medication; D012018:Reflex / Q000187:drug effects*; D012978:Sodium Oxybate / Q000494:pharmacology; D013997:Time Factors
chemical_list: D006885:Hydroxybutyrates; D012978:Sodium Oxybate
vernacular_title: O vliianii oksibutirata matriia na reflektornye gemodinamicheskie reaktsii.