title: [Susceptibility and sensitivity of the Siberian lemming and Middendorff's vole to leptospirae of the grippotyphosa serogroup].
abstract: Siberian lemmings and Middendorf's voles were found to be susceptible to infection caused by Leptospira of the Grippotyphosa serogroup after the intraperitoneal injection of Leptospira culture, the application of the culture or infected urine to the skin, as well as after Leptospira-carrying animals were placed together with the animals to be infected. The infectious sensitivity of these animals to Leptospira was not high: leptospiruria was observed for 1-3 weeks; in some of the voles leptospiruria was slightly pronounced, whereas other voles had a great number of Leptospira in urine. Antibodies appeared in the blood on day 5 after infection, and their titers increased till days 61-63. In no case could Leptospira be isolated from the kidneys of the animals killed on days 61-83 of the experiment.
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D003411:Arvicolinae / Q000382:microbiology*; D005260:Female; D007919:Leptospira / Q000472:pathogenicity*; D007922:Leptospirosis / Q000276:immunology / Q000382:microbiology; D008297:Male; D012377:Rodentia / Q000382:microbiology*; D012800:Siberia; D013997:Time Factors; D014556:Urine / Q000382:microbiology
chemical_list: D000907:Antibodies, Bacterial
vernacular_title: O vospriimchivosti i chuvstvitel'nosti sibirskogo lemminga i polevki Middendorfa k leptospiram serogruppy grippotyphosa.