[Effect on lymphocyte and granulocyte function of levamisole in chronic mucocutaneous candidamycosis].
In 5 patients (3 children, 2 adults) suffering from familial or non-familial chronic muco-cutaneous Candidosis (CMCC) combined with cellular immune deficiencies of different extent, an immunostimulating therapy regimen with levamisole was performed over 6 months. Post-treatment clinical and immunological re-examinations offered a favourable effect on the cellular immune system in all patients. As to the general health condition, in the children all clinical symptoms of CMCC clearly improved or disappeared completely, whereas in both adult patients no satisfactory clinical effect of levamisole therapy could be observed so far.
D000328:Adult; D002179:Candidiasis, Cutaneous / Q000188:drug therapy*; D002634:Chemotaxis, Leukocyte / Q000187:drug effects; D002648:Child; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D003022:Clotrimazole / Q000627:therapeutic use; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006098:Granulocytes / Q000187:drug effects*; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use*; D008214:Lymphocytes / Q000187:drug effects*; D008297:Male; D009761:Nystatin / Q000627:therapeutic use; D010587:Phagocytosis / Q000187:drug effects; D013607:Tablets; D013997:Time Factors
D013607:Tablets; D009761:Nystatin; D007978:Levamisole; D003022:Clotrimazole
Beeinflussung der Lympho- und Granulozytenfunktion durch Levamisol bei chronischer muco-cutaner Candidamycose.