Are class I (pre-early) proteins of bacteriophage T5 sufficient to induce abortive infection of ColIb+ Escherichia coli?
When T5 bacteriophage infect a colicin Ib-containing host, a variety of membrane changes and inhibition of macromolecular synthesis occur. This work shows that all these changes also occur when a mutant of T5 that can only inject 8% of its DNA is used. This indicates that all the information necessary for the abortive infection is present on this 8% (first-step-transfer) DNA.
D003087:Colicins; D003090:Coliphages / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D004926:Escherichia coli / Q000235:genetics / Q000502:physiology*; D005814:Genes, Viral; D005973:Glutamine / Q000378:metabolism; D008757:Methylglucosides / Q000378:metabolism; D010957:Plasmids; D011392:Proline / Q000378:metabolism; D014764:Viral Proteins / Q000502:physiology*
D003087:Colicins; D008757:Methylglucosides; D014764:Viral Proteins; D005973:Glutamine; D011392:Proline