A common differentiation antigen on plaque forming cells and a subpopulation of thymus cells in mice and rats.
A non species specific lymphocyte differentiation antigen is described which can be detected on plaque forming cells and a small fraction of thymocytes of mice and rats. The antigen is absent from a BALB/c plasma cell tumor and is not detectable on Dexamethasone-resistant thymocytes. On the basis of its occurrence the term TPCA (thymus plasma cell antigen) is proposed for the antigen. A monospecific anti TPCA serum could be prepared which enables the detection of the antigen on about 10% of rat thymocytes.
D000818:Animals; D000954:Antigens, Surface / Q000032:analysis*; D006462:Hemolytic Plaque Technique; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D010954:Plasmacytoma / Q000276:immunology; D051381:Rats; D013154:Spleen / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology*
D000954:Antigens, Surface