[Cellular immunity factors in dysentery].
Cellular immune response was studied in 89 adult patients suffering from various clinical forms of acute dysentery, with the use of the lymphocyte blast-cell transformation reaction under the action of a specific antigen (dysenterin) and a nonspecific mitogen (phitohemagglutinin). Functional value of T-lymphocytes proved to be retained in patients with acute dysentery; there was also lymphocyte stimulation by a specific antigen in patients with moderately severe and severe forms of dysentery during the first week of the disease. Specificity of blast-cell transformation of sensitized lymphocytes under the action of dysenterin was shown. Patients with a high percentage of the lymphocyte blast forms displayed a more rapid positive progress of the main clinical indices at the height of the disease than analogous patients with a low blast percentage in the blood. The expediency of using the blast-cell transformation reaction for differential diagnosis and prognosis of moderately severe and severe forms of acute dysentery is discussed.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D004405:Dysentery, Bacillary / Q000276:immunology* / Q000473:pathology; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D007111:Immunity, Cellular; D007420:Intestine, Large / Q000473:pathology; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D012764:Shigella sonnei
Nekotorye faktory kletochnogo immuniteta pri dizenterii.