title: [Gonadotropic function in female Cushing syndrome (author's transl)].
abstract: A study of 38 female Cushing syndromes showed decreased levels of FSH and LH, with normal LH-RH stimulation in most adrenal hyperplasia and benign adenoma, and absent stimulation in carcinoma. The levels were normalized by suppression of hypercorticism. This suggests a blunted gonadotropic function, in female Cushing syndrome, probably at the hypothalamic level. The predominant respective roles of hyperandrogeny in carcinoma and of hypercortisolism in adrenal hyperplasia and benign adenoma seem probable.
mesh_terms: D000236:Adenoma / Q000150:complications; D000310:Adrenal Gland Neoplasms / Q000150:complications; D000311:Adrenal Glands / Q000473:pathology; D002277:Carcinoma / Q000150:complications; D003480:Cushing Syndrome / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology; D006065:Gonadotropins, Pituitary / Q000502:physiology*; D006801:Humans; D006854:Hydrocortisone / Q000502:physiology; D006965:Hyperplasia; D007986:Luteinizing Hormone / Q000097:blood
chemical_list: D006065:Gonadotropins, Pituitary; D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D006854:Hydrocortisone
vernacular_title: Etude de la fonction gonadotrope dans le syndrome de Cushing chez la femme.