Double blind study of meptazinol versus pentazocine and placebo in postoperative pain treatment.
The purpose of this double blind study was to evaluate the efficiency and safety of a new analgesic drug meptazinol, compared to pentazocine and placebo, in patients suffering from postoperative pain. Subjective and objective parameters were controlled. It appeared clearly that meptazinol had a potent analgesic effect with rapid onset, but rather short duration. Analgesic effect of pentazocine appeared more slowly, but persisted for a longer time. The two active drugs had no effects on the objective parameters measured.
D001381:Azepines / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D008621:Meptazinol / Q000494:pharmacology / Q000627:therapeutic use*; D010149:Postoperative Pain / Q000188:drug therapy*; D010423:Pentazocine / Q000494:pharmacology / Q000627:therapeutic use*; D010919:Placebos
D001381:Azepines; D010919:Placebos; D008621:Meptazinol; D010423:Pentazocine