Nonspecific T-lymphocyte mitogenesis by pyrogenic exotoxins from group A streptococci and Staphylococcus aureus.
Group A streptococcal pyrogenic exotoxins types A, B, and C and staphylococcal pyrogenic exotoxin were shown to be potent nonspecific T-lymphocyte mitogens. Adherent cell populations did not significantly affect the nonspecific mitogenicity.
D005098:Exotoxins / Q000494:pharmacology*; D008213:Lymphocyte Activation; D011749:Pyrogens; D013211:Staphylococcus aureus; D013297:Streptococcus pyogenes; D013601:T-Lymphocytes / Q000276:immunology*
D005098:Exotoxins; D011749:Pyrogens