Cultures from thymus and liver cells and blood lymphocytes for chromosome analysis in human abortions.
The authors propose a rapid method for chromosome studies in human abortions as a supplementary or alternative method to embryonic tissue cultures. Cultures were set up from fetal lymphocytes and thymus and liver cells. 72 hours was the longest time necessary to obtain suitable chromosome preparations. A very high rate of success was obtained in the 28 cases studied.
D000022:Abortion, Spontaneous / Q000235:genetics*; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D005260:Female; D005821:Genetic Techniques; D006801:Humans; D008099:Liver / Q000196:embryology* / Q000648:ultrastructure; D008214:Lymphocytes / Q000648:ultrastructure*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D013950:Thymus Gland / Q000196:embryology* / Q000648:ultrastructure