A rapid method for preimmunisation and grafting of mice with ear skin.
A schedule for a histocompatibility test among mice involving preimmunisation with ear skin is described and has been tested with the weak transplantation antigen H-Y in C57BL responder and C3H nonresponder strains. The transplantation technique was tested by autografting, and more than 99% of the operations were successful. The priming method reduces the survival of ear skin grafts in every combination tested.
D000818:Animals; D005260:Female; D006084:Graft Rejection; D006650:Histocompatibility Testing / Q000379:methods*; D007114:Immunization; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H / Q000276:immunology; D008810:Mice, Inbred C57BL / Q000276:immunology; D012737:Sex Factors; D012867:Skin / Q000276:immunology; D016038:Skin Transplantation; D013997:Time Factors