A method for detection of complement cleavage in gingival fluid.
A sensitive method is described for detection of C3 cleavage in gingival fluid taken from sites of both normal and inflamed gingiva. Preliminary data suggest a direct relationship between C3 conversion and the presence of periodontal disease.
D002908:Chronic Disease; D003167:Complement Activation; D003176:Complement C3; D003181:Complement C4; D003773:Dental Plaque / Q000382:microbiology; D005883:Gingival Crevicular Fluid / Q000276:immunology*; D005891:Gingivitis / Q000276:immunology*; D006801:Humans; D007122:Immunoelectrophoresis; D010512:Periodontal Index; D010518:Periodontitis / Q000276:immunology*
D003176:Complement C3; D003181:Complement C4