title: Potential halogenated industrial carcinogenic and mutagenic chemicals. IV. Halogenated aryl derivatives.
abstract: A variety of halogenated aryl derivatives possess significant activity as solvents for pesticides, heat transfer agents, pesticide intermediates, additives for rubber products, intermediates in organic synthesis and as insect repellants and deodorants. Ortho- and para-dichlorobenzenes; 1,2,4-trichloro- and hexachlorobenzene, as well as bromobenzenes and benzylchloride were reviewed principally in terms of their synthesis, areas of utility, stability, distribution, reactivity, levels of exposure, populations at risk, metabolism, carcinogenicity and mutagenicity.
mesh_terms: D000818:Animals; D001593:Benzyl Compounds / Q000633:toxicity; D001969:Bromobenzenes / Q000633:toxicity; D002274:Carcinogens, Environmental; D002722:Chlorobenzenes / Q000633:toxicity; D004781:Environmental Exposure; D006581:Hexachlorobenzene / Q000633:toxicity; D006801:Humans; D006846:Hydrocarbons, Halogenated / Q000633:toxicity*; D009153:Mutagens
chemical_list: D001593:Benzyl Compounds; D001969:Bromobenzenes; D002274:Carcinogens, Environmental; D002722:Chlorobenzenes; D006846:Hydrocarbons, Halogenated; D009153:Mutagens; D006581:Hexachlorobenzene