title: [Influence of cefaclor on experimental pyelonephritis (author's transl)].
abstract: A comparative study on the antibiotic activity of cefaclor and cephradine was performed in an infection and therapy model of acute pyelonephritis in the rat. Pathogens were Escherichia coli and Klebsiella pneumoniae. The antibiotics, which were administered orally, both had a pronounced effect in comparison to the untreated control group. Cefaclor was superior to cephradine in infections caused by K. pneumoniae.
mesh_terms: D000818:Animals; D002433:Cefaclor / Q000627:therapeutic use*; D002506:Cephalexin / Q000031:analogs & derivatives*; D002515:Cephradine / Q000627:therapeutic use; D004927:Escherichia coli Infections / Q000188:drug therapy; D007710:Klebsiella Infections / Q000188:drug therapy; D007711:Klebsiella pneumoniae; D011704:Pyelonephritis / Q000188:drug therapy*; D051381:Rats
chemical_list: D002433:Cefaclor; D002515:Cephradine; D002506:Cephalexin
vernacular_title: Die Beeinflussung der experimentellen Pyelonephritis durch Cefaclor.