Countercurrent immunoelectrophoresis in group B streptococcal disease.
Countercurrent immunoelectrophoresis was used for the detection of group- and type-specific antigens in the body fluids of 61 infants from St. Louis and Indiana with group B streptococcal infections. Urine concentrated using an Amicon filter yielded the highest percentage of positive results; 81% were positive in the St Louis group. When three body fluids (urine, CSF, and blood) were available, at least one was positive for group B streptococcus in 95% of the cases. This study demonstrates the applicability of this test in a tertiary care facility (St Louis) and in smaller hospitals (Indiana) with access to central laboratory.
D000942:Antigens, Bacterial / Q000032:analysis*; D002675:Child, Preschool; D003378:Counterimmunoelectrophoresis; D005069:Evaluation Studies as Topic; D005260:Female; D006764:Hospitals, Community; D006801:Humans; D007122:Immunoelectrophoresis; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000276:immunology; D008297:Male; D013290:Streptococcal Infections / Q000276:immunology*; D013292:Streptococcus agalactiae / Q000276:immunology*
D000942:Antigens, Bacterial