[The role of lipoproteinlipase and hepatic triglyceride lipase in the metabolism of triglyceride-rich lipoproteins (author's transl)].
After intravenous injection of heparin two triglyceride lipases are secreted into the plasma: Lipoproteinlipase and a "hepatic" triglyceride lipase. The properties of these two enzymes are extensively discussed in this review. The different methods of measurement of the two lipases are described in detail. The physiological role of lipoproteinlipase in the catabolism of triglyceride-rich lipoproteins is quite well understood. The function of the hepatic triglyceride lipase is not clear until now. The speculations about the possible role of the so-called "remnants" as a substrate of hepatic triglyceride lipase are discussed. The results of own investigations concerning the possible role of these two enzymes in the triglyceride metabolism under different pathophysiological conditions are presented.
D000906:Antibodies; D050260:Carbohydrate Metabolism; D005215:Fasting; D006493:Heparin; D006801:Humans; D007328:Insulin; D008049:Lipase / Q000378:metabolism*; D008071:Lipoprotein Lipase / Q000378:metabolism*; D008074:Lipoproteins / Q000378:metabolism*; D010740:Phospholipases / Q000378:metabolism; D011479:Protamines; D006435:Renal Dialysis; D014280:Triglycerides / Q000378:metabolism; D014304:Triolein / Q000378:metabolism; D014511:Uremia / Q000378:metabolism
D000906:Antibodies; D007328:Insulin; D008074:Lipoproteins; D011479:Protamines; D014280:Triglycerides; D014304:Triolein; D006493:Heparin; D010740:Phospholipases; D008049:Lipase; D008071:Lipoprotein Lipase
Die Bedeutung der Lipoproteinlipase und der hepatischen Triglyzeridlipase beim Abbau Triglyzerid-reicher Lipoproteine.