[Effect of metabolism products of Shigella sonnei, Sh. flexneri and Sh. shigae on proteolytic activity of the organism connective tissue].
The activity of proteolytic enzymes, neutral proteinases and cathepsins E+D, was determined in homogenates from the tissues of capsules formed around diffusion chambers with shigella (Shigella sonnei, Sh. flexneri, Sh. shigae) 1, 2, 3, 5 and 10 days after their implantation to the abdominal cavity of rabbits. The specific proteolytic activity in the capsule tissues in the experimental variants is higher in all the studied periods than in the control and its singularities depend on the microbe species. The rise in the proteolytic activity is the highest under the effect of the Sh. shigae metabolism products, the influence of Sh. flexneri and Sh. sonnei in this respect is somewhat less pronounced.
D000005:Abdomen / Q000382:microbiology*; D000818:Animals; D002403:Cathepsins / Q000378:metabolism*; D003238:Connective Tissue / Q000201:enzymology* / Q000382:microbiology; D010447:Peptide Hydrolases / Q000378:metabolism*; D011817:Rabbits; D012760:Shigella / Q000378:metabolism*; D012763:Shigella flexneri / Q000378:metabolism; D012764:Shigella sonnei / Q000378:metabolism; D013045:Species Specificity
D002403:Cathepsins; D010447:Peptide Hydrolases
Vliianie produktov zhiznedeiatel'nosti shigell zonne, fleksnera i shiga na proteoliticheskyiu aktivnost' soedinitel'noĭ tkani organizma.