[Morphological changes in the cells of Escherichia coli damaged by nitrous yperite].
Nitrous yperite supressed division of E. coli cells; as a result, filaments and giant abnormal cells appeared. Apparently, giant forms were caused by defects in the cell wall induced by nitrous ypertie due to a mutation in the mon gene of the strain. These cells gave rise to normal cells as well as to small bacteria resembling mini-cell.
D000477:Alkylating Agents; D002455:Cell Division / Q000187:drug effects; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000187:drug effects*; D008858:Microscopy, Phase-Contrast; D009588:Nitrogen Mustard Compounds / Q000494:pharmacology*; D013997:Time Factors
D000477:Alkylating Agents; D009588:Nitrogen Mustard Compounds
Morfologicheskie izmeneniia kletok Escherichia coli, povrezhdennykh azotistym ipritom.