[Tissue compatibility of gentamycin PMMA beads and chains (author's transl)].
In chronic bone tissue infections a very effective local antibiotic therapy can be achieved by temporary implantation of Gentamycin-PMMA beads. Eight weeks later the chains were removed and the surrounding specimens of bone were subjected to histological examination. On the basis of the results, it was established that the beads were encapsulated in neutrophile granulocytes, collagen fibers and foreign giant cells.
D000180:Acrylic Resins / Q000009:adverse effects; D000293:Adolescent; D000328:Adult; D001842:Bone and Bones / Q000473:pathology; D002648:Child; D005260:Female; D005549:Foreign-Body Reaction / Q000473:pathology; D005839:Gentamicins / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000188:drug therapy*; D014677:Pharmaceutical Vehicles; D011109:Polymethacrylic Acids / Q000009:adverse effects
D000180:Acrylic Resins; D005839:Gentamicins; D014677:Pharmaceutical Vehicles; D011109:Polymethacrylic Acids
Gewebsverträglichkeit von Gentamycin-PMMA-Ketten und -Kugeln.