Influence of chronic ethanol vapor inhalation on hepatic parenchymal and Kupffer cell function.
This report evaluates the influence of chronic ethanol vapor inhalation on various facets of liver function as well as induction of hepatic and pulmonary pathology in rats. Chronic ethanol inhalation is associated with minimal hepatic dysfunction, but pronounced induction of metabolic tolerance.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D000431:Ethanol / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D005740:Gases; D007728:Kupffer Cells / Q000187:drug effects*; D008099:Liver / Q000166:cytology / Q000187:drug effects*; D008111:Liver Function Tests; D008297:Male; D011720:Pyrazoles / Q000494:pharmacology; D051381:Rats; D013997:Time Factors; D014280:Triglycerides / Q000378:metabolism
D005740:Gases; D011720:Pyrazoles; D014280:Triglycerides; D000431:Ethanol