title: Synergistic antibacterial activity in vitro of trimethoprim and sulphonamides and the importance of pharmacokinetic properties for optimal therapy.
mesh_terms: D004357:Drug Synergism; D004926:Escherichia coli / Q000187:drug effects*; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D013411:Sulfadiazine / Q000494:pharmacology; D013420:Sulfamethoxazole / Q000494:pharmacology; D013443:Sulfisomidine / Q000494:pharmacology; D013449:Sulfonamides / Q000494:pharmacology* / Q000627:therapeutic use; D014295:Trimethoprim / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D013449:Sulfonamides; D013411:Sulfadiazine; D014295:Trimethoprim; D013420:Sulfamethoxazole; D013443:Sulfisomidine