title: Joint effusions after kidney transplantation.
abstract: Thirty-seven consecutive renal transplant recipients were studied prospectively for joint disease. Six developed arthralgias while corticosteroid doses were being lowered. Eleven patients (30%) developed knee effusions at a mean interval of 10 days following transplantation. Synovial fluids were colorless or very pale yellow, with few leukocytes (mean, 28/mm3). These benign transudative effusions did not correlate with immunologic abnormalities, transplant rejection, crystal deposition, or avascular necrosis and may have been due to high dose oral corticosteroid therapy.
mesh_terms: D000293:Adolescent; D000328:Adult; D003460:Crystallization; D005122:Exudates and Transudates / Q000032:analysis / Q000166:cytology / Q000276:immunology; D005260:Female; D006084:Graft Rejection; D006801:Humans; D007592:Joint Diseases / Q000139:chemically induced / Q000209:etiology* / Q000276:immunology; D016030:Kidney Transplantation; D007719:Knee Joint / Q000187:drug effects; D007958:Leukocyte Count; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D010146:Pain; D013583:Synovial Membrane / Q000473:pathology; D013585:Synovitis / Q000139:chemically induced / Q000209:etiology / Q000276:immunology; D014184:Transplantation, Homologous
chemical_list: D008775:Methylprednisolone