Rapid diagnosis of type III group B streptococcal meningitis by latex particle agglutination.
A latex particle agglutination assay was developed to detect type III group B streptococcal antigen in cerebrospinal fluid. Agglutination was observed in each of 12 initial and 54% of 26 subsequent CSF specimens obtained a mean of 53 hours after the institution of antimicrobial therapy. Latex agglutination was more sensitive than countercurrent immunoelectrophoresis for the detection of type III group B streptococcal antigen in CSF from neonates and young infants with meningitis.
D000942:Antigens, Bacterial / Q000032:analysis; D003378:Counterimmunoelectrophoresis; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007841:Latex Fixation Tests; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D013290:Streptococcal Infections / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D013292:Streptococcus agalactiae
D000942:Antigens, Bacterial