Lymphocyte unresponsiveness to PPD tuberculin in badgers infected with Mycobacterium bovis.
Lymphocyte transformation tests using phytohaemagglutinin and concanavalin A showed that both T and B lymphocytes are functional in tuberculous badgers. Dose response curves indicated that purified protein derivative sensitised lymphocytes were suppressed when cultured in the presence of the antigen.
D000818:Animals; D002335:Carnivora; D003208:Concanavalin A / Q000494:pharmacology; D008213:Lymphocyte Activation; D009163:Mycobacterium bovis; D010835:Phytohemagglutinins / Q000494:pharmacology; D014373:Tuberculin / Q000276:immunology*; D014376:Tuberculosis / Q000276:immunology / Q000662:veterinary*
D010835:Phytohemagglutinins; D014373:Tuberculin; D003208:Concanavalin A