Alterations in phospholipid composition in ethanol tolerance and dependence.
Mammalian cells may retain a limited capacity to alter membrane phospholipid fatty acid composition. This may play a role in adaptation to the presence of ethanol (cellular tolerance) and in the response to the removal of ethanol and the withdrawal syndrome.
D000437:Alcoholism / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000378:metabolism; D004361:Drug Tolerance; D000431:Ethanol / Q000494:pharmacology*; D005227:Fatty Acids / Q000378:metabolism; D006801:Humans; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009186:Myelin Sheath / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D013347:Subcellular Fractions / Q000378:metabolism; D013997:Time Factors
D005227:Fatty Acids; D010743:Phospholipids; D000431:Ethanol