title: [Role of the N-terminal sequence (1-26) in the dimerization of protein L7 in solution].
abstract: Native protein L7 from E. coli ribosomes, oxidized protein and a fragment of protein L7 containing the sequence 27--120 obtained by cleavage of the native protein by cyanogen bromide were investigated by sedimentation analysis. It was found that protein L7 exists in solution in a dimer form while the protein oxidized by hydrogen peroxide and the fragment 27--120 do not form a dimer. On the basis of these investigations a conclusion is made that the ability for dimerization is stimulated by N-terminal regions of the protein L7 molecule.
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D001426:Bacterial Proteins; D004926:Escherichia coli / Q000032:analysis*; D008970:Molecular Weight; D010084:Oxidation-Reduction; D011108:Polymers; D011487:Protein Conformation; D012269:Ribosomal Proteins
chemical_list: D000596:Amino Acids; D001426:Bacterial Proteins; D011108:Polymers; D012269:Ribosomal Proteins
vernacular_title: Rol' N-kontsevoĭ posledovatel'nosti (1-26) dlia dimerizatsii belka L7 v rastvore.