Detection of a cell surface antigen common to a mouse myeloma and a population of mouse thymocytes.
A new antigen termed PTA (plasmocytoma thymus antigen) is described which occurs on 70--80% of mouse thymocytes of all mouse strains tested and on an IgG 2b producing BALB/c plasma cell tumor. PTA is detectable on mouse spleen and lymph node cells. It is absent from liver, brain, bone marrow, and antibody plaque forming cells. PTA is not related to theta antigen and is not detectable on rat thymocytes.
D000818:Animals; D000954:Antigens, Surface / Q000032:analysis*; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology; D005455:Fluorescent Antibody Technique; D007074:Immunoglobulin G; D051379:Mice; D008807:Mice, Inbred BALB C; D008815:Mice, Inbred Strains; D010954:Plasmacytoma / Q000276:immunology*; D013154:Spleen / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology*; D014018:Tissue Distribution
D000954:Antigens, Surface; D007074:Immunoglobulin G