Valproic acid: a new antiepileptic drug with potential side effects of dental concern.
Although the exact mechanism by which valproic acid acts on hemostasis is unknown, an association between the agent and defective blood clotting and spontaneous hemorrhage is evident. This side effect should be considered in the management of dental patients taking the drug for whom treatment involves surgery of the soft tissues.
D000328:Adult; D001777:Blood Coagulation / Q000187:drug effects; D001792:Blood Platelets / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced*; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D009055:Mouth / Q000601:surgery*; D010974:Platelet Aggregation / Q000187:drug effects; D014635:Valproic Acid / Q000009:adverse effects* / Q000378:metabolism / Q000494:pharmacology
D014635:Valproic Acid