title: Control of the receptor for galactose taxis in Salmonella typhimurium.
abstract: The chemotactic response to galactose in wild-type Salmonella typhimurium is not inducible by galactose, but is inducible by fucose, a non-metabolizable analog. In a galactokinase mutant, however, the galactose receptor is inducible by galactose. These data indicate that the concentration of free galactose in the cell controls the levels of the galactose receptor. The intensities of the chemotactic responses were found to vary in proportion to the concentration of galactose receptors. In bacteria with higher levels of galactose receptors, the ribose response is inhibited by galactose. This supports the model in which the ribose and galactose receptors compete for a common component of the signaling system.
mesh_terms: D002633:Chemotaxis; D005643:Fucose / Q000378:metabolism; D005686:Galactokinase / Q000235:genetics; D005690:Galactose / Q000378:metabolism*; D009154:Mutation; D011955:Receptors, Drug / Q000378:metabolism*; D012266:Ribose / Q000378:metabolism; D012486:Salmonella typhimurium / Q000235:genetics / Q000502:physiology*
chemical_list: D011955:Receptors, Drug; D005643:Fucose; D012266:Ribose; D005686:Galactokinase; D005690:Galactose