title: Biochemical characterization of infantile gastroenteritis virus (IGV).
abstract: Enzymic and biophysical studies with purified infantile gastroenteritis virus (IGV) nucleic acid indicated that the virion contained a double-stranded RNA genome of approx. 14 x 10(6) daltons which could be separated by gel electrophoresis into eight bands of RNA which were comprised of 15 RNA species. Two major virus proteins, VP2 (mol. wt. = 135,000) and VP8 (mol. wt. = 40,000), which composed about 85% of the total virion protein, were detected in IGV particles by polyacrylamide gel electrophoresis. Eight additional minor proteins were also resolved.
mesh_terms: D003968:Diarrhea, Infantile / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D005759:Gastroenteritis / Q000382:microbiology*; D006801:Humans; D007223:Infant; D008970:Molecular Weight; D010455:Peptides / Q000032:analysis; D012367:RNA, Viral / Q000032:analysis; D012087:Reoviridae / Q000032:analysis; D014764:Viral Proteins / Q000032:analysis; D014713:Viruses, Unclassified / Q000032:analysis* / Q000648:ultrastructure
chemical_list: D010455:Peptides; D012367:RNA, Viral; D014764:Viral Proteins