title: [Effect of flunarizine (sibelium) on the arterial blood flow (author's transl)].
abstract: 31 patients with intermittent claudication were treated with 10 mg Flunarizine (Sibelium) daily for 6 months. Before the beginning of the trial and after a period of 6 months, a plethysmographic examination was undertaken to determine the reactive hyperemia elicited by a temporary arterial occlusion. 25 patients showed an improvement in at least one of the parameters measured during the reactive hyperemia. Lengthening of the walking distance was also seen at the same time in 24 of these patients. In a further analysis of our results it was shown that in each of the 25 patients those parameters of the reactive hyperemia improved which had deviated furthest from the normal.
mesh_terms: D000328:Adult; D000368:Aged; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006940:Hyperemia / Q000188:drug therapy; D007383:Intermittent Claudication / Q000188:drug therapy*; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use*; D010991:Plethysmography
chemical_list: D010879:Piperazines
vernacular_title: Einfluss von Flunarizin (Sibelium) auf das arterielle Blutstromverhalten.