title: Assessment of the healing potentials of ulcers of the skin by photoplethysmography.
abstract: An objective method of assessing the healing potentials of skin ulcers would eliminate the long waiting period necessary for visual evidence of healing or nonhealing to appear. This would permit the continued conservative treatment for healing ulcers and prompt surgical interventions for those ulcers which are nonhealing. In this preliminary study, the cutaneous blood flow immediately around the ulcer site was studied using the photoplethysmograph. Vigorous cutaneous blood flow shown by good pulsatile wave forms on the photoplethysmograph is shown to be indicative of an ongoing healing process in which spontaneous healing of the ulcer can be predicted. Ulcers with nonpulsatile wave forms fail to heal with conservative management. One patient with nonpulsatile wave forms at the ulcer site showed improvement and eventual healing of the ulcer after undergoing a lumbar sympathectomy. Thus, nonpulsatile blood flow shown by poor wave forms on the photoplethysmograph would suggest early surgical intervention. This method may also aid in determining the extent of surgical excision of the ischemic scar tissue surrounding the chronic skin ulcer.
mesh_terms: D006801:Humans; D007511:Ischemia / Q000628:therapy; D008027:Light; D010991:Plethysmography; D003668:Pressure Ulcer / Q000601:surgery / Q000628:therapy; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply*; D012883:Skin Ulcer / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*