title: Rubeosis iridis generated by insulin hypersensitivity.
abstract: There are important similarities between human and experimental monkey rubeosis iridis. We believe that we have developed a useful primate model to study iris neovascularization and that the possible role of immunity to insulin in the pathogenesis of human diabetic rubeosis iridis warrants further detailed consideration.
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000473:pathology; D003920:Diabetes Mellitus / Q000188:drug therapy; D004195:Disease Models, Animal; D004342:Drug Hypersensitivity / Q000150:complications*; D000882:Haplorhini; D006801:Humans; D006940:Hyperemia / Q000276:immunology; D007114:Immunization; D007249:Inflammation / Q000276:immunology; D007328:Insulin / Q000009:adverse effects; D007498:Iris / Q000098:blood supply* / Q000473:pathology; D008253:Macaca mulatta; D014603:Uveal Diseases / Q000276:immunology / Q000473:pathology
chemical_list: D007328:Insulin