The dilemma of childhood optic gliomas.
A retrospective series reviewing 28 cases of optic glioma in childhood is reported from the Columbus Children's Hospital. The literature is reviewed from a clinical and pathological standpoint; in the pathological literature there is support for consideration of these lesions as a neoplastic entity, but none for designation of these gliomas as "hamartomas." An approach to the management of optic gliomas is presented. Treatment should be tailored to the individual patient; no clear therapeutic protocol appears to be supported by available data.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003390:Cranial Nerve Neoplasms / Q000150:complications / Q000401:mortality / Q000628:therapy*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D007223:Infant; D008297:Male; D009442:Neurilemmoma / Q000150:complications / Q000401:mortality / Q000628:therapy*; D009456:Neurofibromatosis 1 / Q000150:complications; D009897:Optic Chiasm; D009900:Optic Nerve