title: Mutagen specificity in the induction of chromosomal aberrations in somatic cells of Drosophila melanogaster.
abstract: The distribution of chromosomal aberrations between and within chromosomes of male D, melanogaster somatic cells after treatment with UV has been analyzed. -- Distribution of the breaks between chromosomes was largely nonrandom since we found a higher aberration frequency than that expected on the Y chromosome. Moreover, within the chromosomes the aberrations are clustered in the pericentromeric heterochromatic regions. The above distribution is compared with that of the breaks induced by X rays and methyl-methane-sulphonate (MMS) which were distributed in a different pattern.
mesh_terms: D000818:Animals; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects / Q000528:radiation effects; D004331:Drosophila melanogaster / Q000648:ultrastructure; D006570:Heterochromatin / Q000648:ultrastructure; D008297:Male; D008741:Methyl Methanesulfonate / Q000494:pharmacology; D009154:Mutation; D009474:Neurons / Q000648:ultrastructure; D011336:Probability; D012730:Sex Chromosomes / Q000648:ultrastructure; D014466:Ultraviolet Rays; D014965:X-Rays
chemical_list: D006570:Heterochromatin; D008741:Methyl Methanesulfonate