title: Cytogenetic localization of the acid phosphatase-1 gene in Drosophila melanogaster.
abstract: A translocation in which a segment of chromosome 3 is inserted into the Y chromosome was found to contain the acid phosphatase-1 gene (Acph-1). In flies hyperploid for that gene, acid phosphatase-1 levels are proportional to the dose of the gene. The locus is placed within the salivary chromosome subdivisions 99D and 99E on the basis of its inclusion in the translocated segment and on the previous placement of the claret locus. Several chromosomal rearrangements involving heterochromatic breakpoints and euchromatic breakpoints adjacent to 99D-99E were tested for possible postiion-effect variegation of acid phosphatase-1. No decrease in the synthesis of the electorphoretic subunit encoded by the relocated gene was observed within any of the rearrangements.
mesh_terms: D000135:Acid Phosphatase / Q000096:biosynthesis / Q000235:genetics*; D000818:Animals; D002874:Chromosome Mapping; D002875:Chromosomes; D004331:Drosophila melanogaster / Q000201:enzymology / Q000235:genetics*; D004792:Enzyme Precursors / Q000096:biosynthesis; D005796:Genes; D012469:Salivary Glands / Q000648:ultrastructure; D014178:Translocation, Genetic
chemical_list: D004792:Enzyme Precursors; D000135:Acid Phosphatase