title: Acceleration of plasma bicarbonate conversion to carbon dioxide by pulmonary carbonic anhydrase.
abstract: In isolated rabbit lungs perfused with solutions containing little or no carbonic anhydrase activity, nearly complete equilibration between H14CO3- and 14CO2 occurs during a single circulation. This equilibration can be inhibited by blocking pulmonary carbonic anhydrase with acetazolamide.
mesh_terms: D000086:Acetazolamide / Q000494:pharmacology; D000818:Animals; D001639:Bicarbonates / Q000097:blood* / Q000378:metabolism; D002245:Carbon Dioxide / Q000097:blood*; D002256:Carbonic Anhydrases / Q000378:metabolism*; D008168:Lung / Q000201:enzymology* / Q000378:metabolism; D010477:Perfusion; D011817:Rabbits
chemical_list: D001639:Bicarbonates; D002245:Carbon Dioxide; D002256:Carbonic Anhydrases; D000086:Acetazolamide