Intal (sodium cromoglycate) therapy in ulcerative colitis.
Intal was applied intrarectally for the treatment of ulcerative colitis in 39 patients with active pathological process. The drug was insufflated by means of rectoscopic tube at the dosage of 200 mg capsules daily for 15 days. Complete remission of the disease has been achieved in 97 per cent of patients within 2 weeks of the administration of the drug. As a maintenance treatment the patients were given SCG orally (240 mg daily) for a period of 2--3 years. During the course of 2--3 years' observation 93 per cent of patients have been maintained in remission by oral SCG therapy.
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D002214:Capsules; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D004205:Cromolyn Sodium / Q000008:administration & dosage / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012007:Rectum; D012075:Remission, Spontaneous
D002214:Capsules; D004205:Cromolyn Sodium