title: [New sulfonamide-trimethoprim combination, Supristol. Results of a joint therapeutic trial (author's transl)].
abstract: The efficacy of a new low dosage trimethoprim-sulfamoxole combination (Supristol) was tested in a joint therapeutic study in 6 medical clinics or departments and in a general practice. A good therapeutic result (healing) was achieved in about 80% of the 143 patients included in the trial. The preparation was well tolerated. Symptoms of intolerance appeared in only 2% of the cases. It is assumed that the low dosage of the preparation influences the tolerance favorably without affecting the efficacy.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000188:drug therapy; D001799:Blood Sedimentation; D002648:Child; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004338:Drug Combinations; D004357:Drug Synergism; D005260:Female; D005767:Gastrointestinal Diseases / Q000188:drug therapy; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D012141:Respiratory Tract Infections / Q000188:drug therapy; D013449:Sulfonamides / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D014295:Trimethoprim / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy
chemical_list: D004338:Drug Combinations; D013449:Sulfonamides; D014295:Trimethoprim
vernacular_title: Neue Sulfonamid-Trimethoprim-Kombination Supristol. Ergebnisse einer gemeinschaftlichen therapeutischen Prüfung.