The antigen Duclos. A new high frequency red cell antigen related to Rh and U.
An antibody is described which defines a new high frequency red cell antigen, Duclos, whose expression seems to require the presence of both U and Rh fundamental antigens. Apart from the antibody maker's own red cells the only nonreactive samples were from Rhnull U impaired individuals, one example of which was shown however to yield very slight amounts of antibody through absorption-elution tests. Rhmod U weak cells gave very depressed and Rhnull U positive or Rh common U negative cells moderately depressed reactions. The proposita's red cells had an apparently normal Rh-LW condition but their U antigen was significantly decreased. No further Duclos negative individual was found by screening 8,500 blood donors in the Paris area.
D000368:Aged; D001789:Blood Group Antigens; D005260:Female; D006382:Hemadsorption; D006801:Humans; D010641:Phenotype; D012204:Rh-Hr Blood-Group System
D001789:Blood Group Antigens; D012204:Rh-Hr Blood-Group System