title: [Humoral immunity aspects of meningococcal infection. I. A method of performing and the characteristics of the immune bacteriolysis reaction].
abstract: Immune bacteriolysis test with meningococcus, group A, was used for the purpose of serum antibody study. Meningococcus cultures with a bright orange fluorescence of the colonies in oblique illumination (the I type) proved to possess the greatest lysability. Guinea pig serum sorbed with meningococcus suspension was found to be the best source of the complement. Sera obtained after 1 to 3 days of rabbit immunization, containing mostly IgM antibodies, had the greatest bactericidal capacity. Only those fractions which contained IgM possessed bactericidal activity in the hyperimmune rabbit sera with a high IgG antibody concentration. No lytic activity was displayed against meningococcus by unfractionated hyperimmune sera.
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D001433:Bacteriolysis; D006168:Guinea Pigs; D007106:Immune Sera / Q000276:immunology; D007109:Immunity; D007114:Immunization; D007158:Immunologic Techniques; D008589:Meningococcal Infections / Q000276:immunology*; D009345:Neisseria meningitidis / Q000276:immunology; D011817:Rabbits; D013997:Time Factors
chemical_list: D000907:Antibodies, Bacterial; D007106:Immune Sera
vernacular_title: Nekotorye aspekty gumoral'nogo immuniteta pri meningokokkovoĭ infektsii. Soobshchenie I. Metodika postanovki i osobennosti reaktsii immunogo bakterioliza.