title: An indirect haemagglutination test for demonstration of gonococcal antibodies using gonococcal pili as antigen. I. Methodology and preliminary results.
abstract: An indirect haemagglutination (IHA) test for detection of gonococcal antibodies in human sera was established using purified pili as antigen. The majority of sera (44/51), positive in the gonococcal complement fixation test, were also positive in the IHA test with titres within the range 320-10,000. The results obtained for the following three groups of sera indicate a comparatively high speicificity of the IHA test; 1) 52 sera from children below 12 years of age were all negative, 2) 98% (184/188) of sera from blood donors were negative, 3) only sera from three adults out of 21 patients with meningococcal infections gave a positive reaction.
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D000942:Antigens, Bacterial; D002021:Buffers; D002648:Child; D003168:Complement Fixation Tests; D006386:Hemagglutination Tests / Q000379:methods*; D006801:Humans; D009344:Neisseria gonorrhoeae / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D002021:Buffers