[Influence of TRH on the depressive syndrome (author's transl)].
In two cases of chronic endogenous depression changes of mood and drive have been investigated over a period of 26 days by self rating scales "ESTA". After a single dose of 250 microgramm TRH a small antidepressive effect and a clear shift of the syndrome in the direction of a mixed state could be demonstrated thus suggesting an increased desintegration of the mood-drive-system.
D000328:Adult; D002908:Chronic Disease; D003527:Cyclothymic Disorder / Q000188:drug therapy; D003863:Depression / Q000188:drug therapy*; D004341:Drug Evaluation; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D013973:Thyrotropin-Releasing Hormone / Q000008:administration & dosage / Q000627:therapeutic use*
D013973:Thyrotropin-Releasing Hormone
Bemerkungen zum Effekt von Thyreotropin-releasing-hormone (TRH) auf das depressive Syndrom.