Listericidal activity of non-stimulated and stimulated human macrophages in vitro.
An in vitro biological assay system has been described to quantify the listericidal activity of human macrophages grown from peripheral blood monocytes. Within 15 min after in vitro infection, the activated macrophages showed a faster and higher degree in killing capacity as compared to the nonactivated ones; the killing process early and was of short duration.
D006801:Humans; D066298:In Vitro Techniques; D008089:Listeria monocytogenes / Q000187:drug effects / Q000276:immunology*; D008213:Lymphocyte Activation; D008264:Macrophages / Q000187:drug effects / Q000276:immunology*; D010400:Penicillin G / Q000494:pharmacology; D010587:Phagocytosis; D013997:Time Factors
D010400:Penicillin G