title: Correlation of encystment and Division in Schizopyrenus russelli.
abstract: Schizopyrenus russelli, a free-living soil ameba, grows and encysts in the presence of bacteria. The encystment occurs with decline in the division rate. This is accompanied by incorporation of [U-14C] glucose into cyst cellulose. The degree of multiplication (but not of encystment) is a function of bacterial concentration. Berenil, a trypanocidal drug, while allowing excystment, completely inhibited multiplication of emerged amebae and their encystment. Addition of this drug after 24 hr, when amebae had gone into a phase of active division failed to check encystment, although it still inhibited further multiplication of the amebae. The findings suggest that a phase of cell division may be a prerequisite for encystment.
mesh_terms: D000818:Animals; D002455:Cell Division; D003470:Culture Media; D004247:DNA / Q000096:biosynthesis; D013769:Tetrahymena pyriformis / Q000166:cytology* / Q000378:metabolism; D013997:Time Factors
chemical_list: D003470:Culture Media; D004247:DNA