title: Hormonal regulation of intraocular pressure.
abstract: A detailed review of the hormonal effects on intraocular pressure is presented. There is evidence that corticotropin, vasopressin, thyroxin, insulin, glucocorticoids and mineralocorticoids may play a role in the physiologic regulation of intraocular pressure. Growth hormone, melanocyte stimulating hormone, progesterone, estrogen, chorionic gonadotropin and relaxin may influence intraocular pressure when administered in pharmacologic doses. Whether the key to understanding primary open-angle glaucoma lies in recognizing abnormal endocrine mechanisms, especially involving glucocorticoids, remains unclear at the present time.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000494:pharmacology; D000328:Adult; D000818:Animals; D002415:Cats; D006063:Chorionic Gonadotropin / Q000494:pharmacology / Q000502:physiology; D003339:Corpus Luteum Hormones / Q000494:pharmacology / Q000502:physiology; D004285:Dogs; D004967:Estrogens / Q000494:pharmacology / Q000502:physiology; D005260:Female; D005901:Glaucoma / Q000503:physiopathology*; D000882:Haplorhini; D006728:Hormones / Q000502:physiology*; D006801:Humans; D007328:Insulin / Q000494:pharmacology / Q000502:physiology; D007429:Intraocular Pressure / Q000187:drug effects; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000494:pharmacology / Q000502:physiology; D010907:Pituitary Hormones / Q000494:pharmacology / Q000502:physiology; D011247:Pregnancy; D011817:Rabbits; D013739:Testosterone / Q000494:pharmacology / Q000502:physiology; D013974:Thyroxine / Q000494:pharmacology / Q000502:physiology
chemical_list: D000305:Adrenal Cortex Hormones; D006063:Chorionic Gonadotropin; D003339:Corpus Luteum Hormones; D004967:Estrogens; D006728:Hormones; D007328:Insulin; D010281:Parathyroid Hormone; D010907:Pituitary Hormones; D013739:Testosterone; D013974:Thyroxine