title: [Pathophysiology and disgnosis of autonomous adenoma (author's transl)].
abstract: From personal experience in 200 patients and after a careful review of the literature autonomous adenoma of the thyroid is discussed under three aspects: 1. Different ways of its pathogenesis are possible. None of them has been sufficiently proven. 2. Differentiation by scintigraphy into a compensated, partially decompensated stage does not correlate sufficiently with the concentration of thyroid hormones in the blood and the overall clinical picture. The TRH test is negative in about 90% of patients independent of the stage evaluated by scintigraphy. 3. The diagnosis of the disease by modern tools is critically reviewed.
mesh_terms: D000236:Adenoma; D006801:Humans; D011877:Radionuclide Imaging; D013961:Thyroid Gland; D013963:Thyroid Hormones / Q000097:blood; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D013973:Thyrotropin-Releasing Hormone
chemical_list: D013963:Thyroid Hormones; D013973:Thyrotropin-Releasing Hormone
vernacular_title: Pathophysiologie und Diagnostik des autonomen Adenoms