title: Metals as mutagens.
abstract: A number of metals are mutagenic in bacteria or phage. These include compounds of arsenic, chromium, copper, iron, manganese, molybdenum, platinum, and selenium. Compounds containing alumium, antimony, arsenic, cadmium, copper, lead, mercury, nickel, and tellium have been shown to induce chromosomal aberrations or abnormal cell divisions in animal or plant cells. Genetic evidence suggests that arsenic, chromium, and molybdenum compounds may influence the accuracy of DNA repair processes in microorganisms.
mesh_terms: D000818:Animals; D001412:Bacillus subtilis / Q000235:genetics; D002273:Carcinogens; D002869:Chromosome Aberrations; D004260:DNA Repair; D004781:Environmental Exposure; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics; D006801:Humans; D008670:Metals / Q000494:pharmacology* / Q000633:toxicity; D009153:Mutagens; D009154:Mutation; D009369:Neoplasms / Q000139:chemically induced / Q000235:genetics; D011995:Recombination, Genetic; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics
chemical_list: D002273:Carcinogens; D008670:Metals; D009153:Mutagens