Experimental microvascular anastomoses in radiated vessels: a study of the patency rate and the histopathology of healing.
A study of microvascular surgery in radiated tissue is presented. The radiation damage to the vessels and its consequence on the histopathology of blood vessel healing is discussed. The main difficulty encountered was the radiation-induced fibrosis in the perivascular tissues. The patency rate in ther arterial anastomoses was unaltered by prior radiation, but the patency rate in the venous anastomoses fell to 54 percent after high doses of prior radiation.
D000818:Animals; D001808:Blood Vessels / Q000473:pathology / Q000528:radiation effects*; D005263:Femoral Artery / Q000473:pathology / Q000528:radiation effects / Q000601:surgery; D007084:Iliac Vein / Q000473:pathology / Q000528:radiation effects / Q000601:surgery; D008866:Microsurgery; D011829:Radiation Dosage; D051381:Rats; D012867:Skin / Q000528:radiation effects; D014656:Vascular Surgical Procedures; D014945:Wound Healing