Relevance of specific activity in experimental erythrocytocide by 55Fe.
Iron loads between 0.20 microgram and 26 microgram, added to 5 mu Ci 59Fe, were followed for up to 150 days in mice. Relative organ uptake increased as a function of iron load in liver and kidneys while it decreased in bone marrow and blood. Several weeks after injection, all load-related differences disappeared.
D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D004912:Erythrocytes / Q000528:radiation effects*; D004920:Erythropoiesis / Q000528:radiation effects; D007504:Iron Radioisotopes / Q000008:administration & dosage; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D051379:Mice; D013997:Time Factors; D014018:Tissue Distribution
D007504:Iron Radioisotopes