title: [Central nervous manifestations of neurofibromatosis in children (author's transl)].
abstract: Serious central nervous manifestation of neurofibromatosis have been reported in 11 children aged 1,5-12 years. According to the present literature we conclude: 1. Central nervous lesions of neurofibromatosis are common even in childhood. 2. About two thirds of these patients suffer from brain tumors. 3. The tumors involve the suprasellar region in many cases. 4. By this localisation endocrine manifestations, especially precocious puberty, are frequent.
mesh_terms: D001254:Astrocytoma / Q000150:complications; D001827:Body Height; D001932:Brain Neoplasms / Q000150:complications; D002493:Central Nervous System Diseases / Q000150:complications / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006130:Growth Disorders / Q000150:complications; D006801:Humans; D006849:Hydrocephalus / Q000150:complications; D007223:Infant; D008297:Male; D009456:Neurofibromatosis 1 / Q000150:complications*; D009461:Neurologic Manifestations; D009896:Optic Atrophy / Q000150:complications; D011629:Puberty, Precocious / Q000150:complications; D012658:Sella Turcica
vernacular_title: Zentralnervöse Erkrankungen bei Kindern mit Neurofibromatose von Recklinghausen.