title: [Exocrine secretion of pancreatic carcinomas induced by immunologic effects: persistence of the specificity of the cancerous ascitic pancreatic cells].
abstract: Pancreatic carcinomas electively induced by immunological mechanism [(1), (2)] keep their exocrine secretory specificity along the various stages of their evolution: (a) during the transformation phase from adenoma to carcinoma; (b) in the evolved carcinoma; (c) in its metastasis; (d) in the ascitic carcinomatous cells formed. They are called: immuno-inducted carcinoma. The carcinomatous cells of the constantly deadly ascites cease their production of secretion granules after passages by intraperitoneal graft; but this secretion reappears in the solid carcinomas they induce by subcutaneous graft and contains trypsinogen and chymotrypsinogen, even after the 92nd passage, at the 757 day. Besides, the antisera (1) enhance the growth and the affinity for pancreas and adipose tissue of the carcinomatous ascitic strains they induced. They, sometimes, produce nodular hepatic carcinomas.
mesh_terms: D000906:Antibodies; D001201:Ascites / Q000378:metabolism*; D002277:Carcinoma / Q000378:metabolism*; D002919:Chymotrypsinogen / Q000378:metabolism; D008071:Lipoprotein Lipase / Q000276:immunology; D008198:Lymph Nodes; D008207:Lymphatic Metastasis; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000378:metabolism; D010190:Pancreatic Neoplasms / Q000209:etiology / Q000378:metabolism* / Q000473:pathology; D014362:Trypsinogen / Q000378:metabolism
chemical_list: D000906:Antibodies; D014362:Trypsinogen; D002919:Chymotrypsinogen; D008071:Lipoprotein Lipase
vernacular_title: Sécrétion exocrine du carcinome du pancréas induit par effet immunologique: persistance de la spécificité de la cellule pancréatique carcinomateuse ascitique