title: Effect of high-power density microwave irradiation on the soluble proteins of the rabbit lens.
abstract: New Zealand rabbits were irradiated on the left side of the head by microwaves (2.45 GHz) at 300 mw/cm2 for 20 min on each of 2 consecutive days. Lens changes in irradiated animals, observed by biomicroscopy, ranged from no changes to small posterior subcapsular opacities. Pore-gradient electrophoresis was used to examine the distribution of soluble lens proteins. A marked difference in soluble protein distribution of the lens cortex and nucleus was observed. Comparison of irradiated and control lenses revealed an apparent shift toward higher-molecular-weight components in the cortex samples of the microwave-irradiated lenses.
mesh_terms: D000818:Animals; D002386:Cataract / Q000209:etiology* / Q000473:pathology; D004195:Disease Models, Animal; D004591:Electrophoresis, Polyacrylamide Gel; D005136:Eye Proteins / Q000032:analysis*; D007908:Lens, Crystalline / Q000032:analysis / Q000473:pathology / Q000528:radiation effects*; D008872:Microwaves / Q000009:adverse effects*; D008970:Molecular Weight; D011817:Rabbits
chemical_list: D005136:Eye Proteins