Intraspinal metastases from retinoblastoma.
Cerebrospinal fluid seeding is a well-known mode of metastasis for intracranial neoplasms such as medulloblastoma, ependymoma, and glioblastoma; however, retinoblastoma is not usually considered. The route of spread appears to be by direct extension into the optic nerve from the retina and into the meningeal spaces by extension from the choroid, or along the central retinal vessels to the subarachnoid space. Four cases are presented.
D002675:Child, Preschool; D003390:Cranial Nerve Neoplasms / Q000150:complications; D005134:Eye Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D009901:Optic Nerve Diseases / Q000150:complications; D011859:Radiography; D012175:Retinoblastoma / Q000473:pathology*; D013120:Spinal Cord Neoplasms / Q000000981:diagnostic imaging* / Q000209:etiology