title: Corneal transplantation for endothelial pigmentation.
abstract: Endothelial pigmentation does not usually interfere with vision. This case report documents a dense and extensive deposition of uveal pigment in corneal endothelial cells of a patient who had undergone 2 previous grafts subsequent to an alkali burn injury. The previous graft in which the pigmentation occurred remained compensated, but vision was impaired secondary to dense endothelial pigmentation. A combination of the initial chemical injury, recurrent iritis, chronic glaucoma, and multiple intraocular procedures may have resulted in the stimulus for the uveal tract to disperse a large amount of pigment onto the cornea and its subsequent phagocytosis by the endothelium. Endothelial pigmentation may become a more commonly seen complication in attempts to treat the severely damaged anterior segment.
mesh_terms: D000328:Adult; D002057:Burns, Chemical / Q000150:complications; D003315:Cornea / Q000473:pathology; D003316:Corneal Diseases / Q000209:etiology / Q000601:surgery*; D016039:Corneal Transplantation; D004727:Endothelium / Q000473:pathology; D005126:Eye Burns / Q000139:chemically induced / Q000150:complications; D005901:Glaucoma / Q000150:complications; D006801:Humans; D007500:Iritis / Q000150:complications; D008297:Male; D010859:Pigmentation Disorders / Q000601:surgery*; D014184:Transplantation, Homologous