title: [Etiology and pathogenesis of multiple sclerosis].
abstract: The features of the clinical picture and pathomorphology are analysed in 23 patients with disseminated sclerosis (in the acute, subacute and chronic phases). A clinico-anatomical observation of a subacute development of disseminated sclerosis is described in detail. Certain arguments distinguishing the subacute form of disseminated sclerosis of an infectious allergic nature are given (the traits of the clinical picture, morphological changes in the nervous system in the form of combined micronecrosis, pericellular oedema, different degrees of lymphocyte infiltration, extensive areas with accumulated oligodendroglia or fibrillar astrocytes with fresh and old foci of demyelinization).
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D013116:Spinal Cord / Q000473:pathology*; D014777:Virus Diseases / Q000150:complications
vernacular_title: K etiologii i patogenezu rasseiannogo skleroza.