title: [Geycogen content and the enzymatic system of its biosynthesis in normal and tumorous human tissues].
abstract: In human tumors (cancer of the liver, stomach, lymphogranulomatosis of lymphnodes, metastases in lymphnodes, ascites ovarian tumor cells) the authors studied the content of enzymes participating in glycogen biosynthesis through uridine diphosphateglucose mechanism--UDPG-glycogensynthetase, UDPG-pyrophosphroylase, phosphoglucomutase. As a rule, in human tumor cells the amount of glycogen and the activity of enzymes of its biosynthesis is decreased, the more the higher proliferative activity and autonomization of tumor cells.
mesh_terms: D004789:Enzyme Activation; D006003:Glycogen / Q000096:biosynthesis* / Q000378:metabolism; D006006:Glycogen Synthase / Q000378:metabolism; D006801:Humans; D008113:Liver Neoplasms / Q000378:metabolism; D008223:Lymphoma / Q000378:metabolism; D009369:Neoplasms / Q000378:metabolism*; D009713:Nucleotidyltransferases / Q000378:metabolism*; D010733:Phosphoglucomutase / Q000378:metabolism; D013274:Stomach Neoplasms / Q000378:metabolism; D005957:UTP-Glucose-1-Phosphate Uridylyltransferase / Q000378:metabolism*; D014532:Uridine Diphosphate Glucose / Q000378:metabolism*; D014539:Uridine Diphosphate Sugars / Q000378:metabolism*
chemical_list: D014539:Uridine Diphosphate Sugars; D006003:Glycogen; D006006:Glycogen Synthase; D009713:Nucleotidyltransferases; D005957:UTP-Glucose-1-Phosphate Uridylyltransferase; D010733:Phosphoglucomutase; D014532:Uridine Diphosphate Glucose
vernacular_title: Soderzhanie glikogena i énzimaticheskaia sistema ego biosintez v normal'nykh i opukholevykh tkaniakh cheloveka