Peripheral uveitis in the owl monkey. Experimental model.
Primary intravitreous HA injections cause a great variation in ocular inflammatory response, ranging from slight Tyndall effect (LI-HA) to severe inflammation (HI-HA). Both slight and severe inflammation are transient and subside completely within 10-30 days (early inflammatory response), whereas multiple injections ( greater than 3 times) cause a peripheral uveitis, which can be of interest as an experimental model. Control experiments with endotoxin (endotoxin uveitis) fail to produce the same or similar pathological alterations.
D000818:Animals; D001029:Aotus trivirgatus; D004731:Endotoxins; D005260:Female; D000882:Haplorhini; D006820:Hyaluronic Acid; D008297:Male; D012485:Salmonella typhi; D014605:Uveitis / Q000139:chemically induced* / Q000473:pathology
D004731:Endotoxins; D006820:Hyaluronic Acid