[Combined treatment of lung cancer].
Since 1963 to 1975 one hundred and eighty eight patients were subjected to surgery with preoperative irradiation, using a betatron of 25 M. e. v. Irradiation was carried on during 2--3 weeks from 2 or 3 fields daily. A total focal dose ranged within the limits from 2500 to 4500 rad. Radical operations were performed in 159 patients, the mortality being 6.7%. The survival over 3 years--in 69.1%, over 5 years--in 57.3%. Postoperative irradiation using a betatron of 25 M. e. v. is found to contribute to an improvement of general condition in lung cancer patients and to render a positive effect on clinical and roentgenological signs of the disease. A comparative morphological study of diagnostic biopsy specimens and lung preparations, removed following irradiation, indicates various degree of cancer pathomorphosis up to tumor disappearrance and development of radiation sclerosis.
D000230:Adenocarcinoma / Q000473:pathology / Q000628:therapy; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011300:Preoperative Care; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy / Q000009:adverse effects
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