title: Intestinal absorption of 65 Zinc in A46 (Adema disease) after treatment with oxychinolines.
abstract: In two calves with the genetic defect A46 (Adema disease) intestinal absorption of 65Zn was increased during a period of oral treatment with oxychinolines. Oral supplementation with zinc oxide resulted in extremely high plasma zinc concentrations and a moderate increase in 65Zn absorption.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy* / Q000235:genetics; D006912:Hydroxyquinolines / Q000627:therapeutic use*; D007408:Intestinal Absorption / Q000187:drug effects*; D008286:Malabsorption Syndromes / Q000188:drug therapy / Q000235:genetics / Q000662:veterinary*; D015125:Oxyquinoline / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D015032:Zinc / Q000097:blood; D015034:Zinc Oxide / Q000627:therapeutic use
chemical_list: D006912:Hydroxyquinolines; D015125:Oxyquinoline; D015032:Zinc; D015034:Zinc Oxide