Ceramide metabolism in brain.
Ceramide is the fundamental structure and key intermediate of all sphingolipids. Biosynthesis and catabolism of brain ceramide, especially their relationship to the metabolism of more complex sphingolipids in brain, are reviewed. Human genetic diseases which involve altered ceramide metabolism are also discussed.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002518:Ceramides / Q000096:biosynthesis / Q000378:metabolism*; D005227:Fatty Acids / Q000378:metabolism; D005732:Gangliosides / Q000378:metabolism; D006801:Humans; D008052:Lipid Metabolism, Inborn Errors / Q000378:metabolism; D013107:Sphingolipids / Q000378:metabolism; D013110:Sphingosine / Q000378:metabolism
D002518:Ceramides; D005227:Fatty Acids; D005732:Gangliosides; D013107:Sphingolipids; D013110:Sphingosine