Derivatives of 4(7)-methyl- and 5,6-dimethyl-benzimidazolyl-2-mercaptoacetic acids.
Esters, hydrazides and hydrazones of the in title mentioned acids were prepared and screened for tuberculostatic activity. The strongest activity (MIC at 15-6 mug/cm3) was shown by hydrazide 4 and its hydrazone 4a.
D000995:Antitubercular Agents / Q000138:chemical synthesis*; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis / Q000494:pharmacology
D000995:Antitubercular Agents; D001562:Benzimidazoles; D013438:Sulfhydryl Compounds