Ethanol, pentobarbital, and chlordiazepoxide effects in squirrel monkeys responding under fixed-ratio food presentation and stimulus-shock termination schedules.
Ethanol, pentobarbital, and chlordiazepoxide were administered to squirrel monkeys responding under a multiple schedule comprised of two fixed-ratio 100-response schedules (FR 100). Under one FR schedule, the one-hundredth response produced food. Under the other schedule, the one-hundredth response terminated the prevailing stimuli and accompanying schedule of electric shock presentation (stimulus-shock termination). Comparable high response rates were maintained under the two schedules. Each drug produced dose-related decreases in response rates. With all three drugs the effects on all aspects of performance were quantitatively similar for both stimulus-shock termination and food-maintained responding.
D000818:Animals; D002707:Chlordiazepoxide / Q000494:pharmacology*; D003216:Conditioning, Operant / Q000187:drug effects*; D003864:Depression, Chemical; D004597:Electroshock; D000431:Ethanol / Q000494:pharmacology*; D000882:Haplorhini; D008297:Male; D010424:Pentobarbital / Q000494:pharmacology*; D011678:Punishment; D012055:Reinforcement Schedule; D012201:Reward; D012453:Saimiri
D000431:Ethanol; D002707:Chlordiazepoxide; D010424:Pentobarbital