Pulmonary and rhinocerebral mucormycosis. Successful outcome with amphotericin B and griseofulvin therapy.
An ominous prognosis is associated with combined pulmonary and rhinocerebral mucormycosis (phycomycosis). We report the case of a diabetic patient with ketoacidosis who had extensive pulmonary and rhinocerebral mucormycosis that responded satisfactorily to amphotericin B and griseofulvin therapy. The affected lung is completely atelectatic and has remained so for 12 months without evidence of necrosis or abscess formation.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D001927:Brain Diseases / Q000150:complications / Q000188:drug therapy*; D016883:Diabetic Ketoacidosis / Q000150:complications; D005260:Female; D006118:Griseofulvin / Q000627:therapeutic use*; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications / Q000188:drug therapy*; D009091:Mucormycosis / Q000150:complications / Q000188:drug therapy*; D009668:Nose Diseases / Q000150:complications / Q000188:drug therapy*; D011379:Prognosis
D006118:Griseofulvin; D000666:Amphotericin B