The major histocompatibility complex of rhesus monkeys, RhL--A. VII. Identification of five new serologically defined antigens.
Five new serologically defined (SD) tissue antigens of rhesus monkeys are described. Results of a population study and a segregation analysis in families were consistent with their control by the major histocompatibility complex (MHC), as alleles of the two previously established SD loci of RhL--A. The number of identifiable SD specificities of the rhesus monkeys' MHC is now twenty-five, thirteen controlled by the SD1 locus and twelve by SD2. The recombination frequency between SD1 and SD2 is estimated to be 0.3%. No evidence of a third SD series, as analogue of the human HLA--C locus, has yet been found.
D000818:Animals; D001792:Blood Platelets; D005838:Genotype; D006238:Haploidy; D000882:Haplorhini; D006649:Histocompatibility Antigens / Q000032:analysis*; D007106:Immune Sera / Q000494:pharmacology; D007163:Immunosorbent Techniques; D008253:Macaca mulatta; D010641:Phenotype; D011995:Recombination, Genetic
D006649:Histocompatibility Antigens; D007106:Immune Sera