title: Effect of pemphigus antibodies on desmosomal structure in vitro.
abstract: Changes in desmosomes were noted in nonacantholytic regions of skin explants cultured in the presence of intercellular antibodies. These changes included dissociation of desmosomes, as well as a "selective loss" of desmosomal components in one or both of neighboring cells.
mesh_terms: D000051:Acantholysis / Q000276:immunology / Q000473:pathology; D000818:Animals; D000906:Antibodies / Q000008:administration & dosage*; D002450:Cell Communication / Q000187:drug effects; D003896:Desmosomes / Q000187:drug effects / Q000276:immunology / Q000648:ultrastructure*; D000882:Haplorhini; D006801:Humans; D008253:Macaca mulatta; D010392:Pemphigus / Q000276:immunology* / Q000473:pathology; D012867:Skin / Q000276:immunology / Q000648:ultrastructure
chemical_list: D000906:Antibodies