The Axenfeld syndrome and the Rieger syndrome.
A family is reported in which both the syndrome of Axenfeld and the eye malformations of the syndrome of Rieger occur, indicating that both may be expressions of the same gene. We also review the associated anomalies already reported, emphasise their high incidence, suggest that these are not accidental associations, and propose some possible explanations for the high incidence.
D000867:Anterior Chamber / Q000002:abnormalities*; D005124:Eye Abnormalities; D005260:Female; D005796:Genes; D005901:Glaucoma / Q000235:genetics*; D006801:Humans; D008297:Male; D010375:Pedigree; D013577:Syndrome; D014071:Tooth Abnormalities / Q000235:genetics*