Relation between total serum IgE levels and IgE antibody production in rats.
Five different rat strains were immunized with 100 microgram ovalbumin and 1 mg Al (OH)3. A good correlation was found between the total serum IgE level of a rat strain before immunization and the IgE antibody production. Good IgE antibody-producing strains had high total serum IgE levels and vice versa. A discordance between the evolution of the total serum IgE level after immunization and the changes in IgE antibody level was found in all strains.
D000818:Animals; D000917:Antibody Formation; D007114:Immunization; D007073:Immunoglobulin E / Q000096:biosynthesis*; D008297:Male; D051381:Rats; D011914:Rats, Inbred BN
D007073:Immunoglobulin E