title: [The hypothesis of the genetic transmission (autosomal recessive) of subtypes of HBs Ag. The example of Kel Kummer].
abstract: In a study of asymtomatic carriers of hepatitis B surface antigen (HBs Ag) in a closed population, the Twareg Kel Kummer, 18% of the population (79 individuals out of 439 tested) were found to be carriers of one of the 3 sub types: HBs Ag/a2 1 dw, HBs Ag/a2 1 yw and HBs Ag/a3 yw. Evidence from genealogies and the distribution of carriers in the pyramid of ages strongly supports the hypothesis of genetic transmission of the gene sub type as an autosomal recessive.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002353:Carrier State / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D005260:Female; D005787:Gene Frequency; D005808:Genes, Recessive; D006509:Hepatitis B / Q000235:genetics; D006514:Hepatitis B Surface Antigens / Q000145:classification / Q000235:genetics*; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007223:Infant; D008297:Male; D008302:Mali; D008875:Middle Aged
chemical_list: D006514:Hepatitis B Surface Antigens
vernacular_title: Contribution à l'hypothèse de la transmission génétique (autosomale récessive) des sous-types du HBs Ag. L'exemple des Kel Kummer.