[Action of hyperoxia on hemolytic activity of the complement system].
Normobarie oxygen exposures momentarily raise by about 20% the haemolytic activity of the guinea pig complement likely by a rise of protein synthesis. About the end of this treatment the complement activity quickly decreases back to its initial value. Hyperbaric oxygen exposure immediately decreases the haemolytic activity. This shift might be result of a release in the serum of cytoplasmic elements bearing an anticomplementary activity or of an inactivation of the complement components involved in the stress reaction appearing in the treated animals. 2 days after the first exposure, during the resting phase, the complement rate increases by about 25% then decreases slowly back to normal.
D000818:Animals; D003169:Complement Inactivator Proteins; D003165:Complement System Proteins / Q000502:physiology*; D006168:Guinea Pigs; D006461:Hemolysis; D006931:Hyperbaric Oxygenation; D008297:Male; D010100:Oxygen; D011312:Pressure; D013312:Stress, Physiological
D003169:Complement Inactivator Proteins; D003165:Complement System Proteins; D010100:Oxygen
Action de l'hyperoxie sur l'activité hémolytique du système du complément