Effect of bleeding on in vivo in vitro colony-forming hemopoietic cells.
The effect of bleeding on spleen colony-forming units (CFU-S) and on in vitro colony-forming cells with colony-stimulating factor (CFU-C) and erythropoietin (CFU-E) has been evaluated. The in vivo and in vitro colony-forming cells of the bone marrow show a decrease which for the CFU-E, CFU-C follows a short-lived increase. In the spleen, all progenitor cells assayed have shown a significant and sustained increase.
D000818:Animals; D002455:Cell Division; D002999:Clone Cells; D003115:Colony-Stimulating Factors; D004921:Erythropoietin; D006412:Hematopoietic Stem Cells / Q000502:physiology*; D006470:Hemorrhage; D051379:Mice; D008815:Mice, Inbred Strains; D013154:Spleen / Q000166:cytology*
D003115:Colony-Stimulating Factors; D004921:Erythropoietin