title: [Treatment of hypertension with propranolol in internal medicine and general practice. A field trial with a simplified twice daily administration of Dociton 80 (author's transl)].
abstract: More recent investigations on the duration of effect and plasma half-life of propranolol suggest a simplification of dosage for the beta-blocker in the treatment of hypertension. A field trial with Dociton 80 twice daily as initial therapy was carried out in over 2000 patients with essential hypertension with relatively few side effects and confirmed the distinctly longer-persisting effect of the beta-blocker on longterm application. Including the marginal values, the response rate in this collective was relatively high at 73%.
mesh_terms: D001919:Bradycardia / Q000139:chemically induced; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011433:Propranolol / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D011674:Pulse / Q000187:drug effects; D014717:Vertigo / Q000139:chemically induced
chemical_list: D011433:Propranolol
vernacular_title: Hypertoniebehand-lung mit Propranolol in der internistischen und Allgemeinpraxis. Eine Feldstudie mit vereinfachter, zweimal täglicher Verabreichung von Dociton 80.