[Model of the effect of 4-aminopyridine at the level of potassium channels of the giant axon of the squid, Logigo forbesi L].
Most of the effects of 4-aminopyridine on the potassium conductance of the giant axon of the Squid can be explained in terms of a simple model based on the physicochemical properties of the molecule and what is known about the structure of the potassium "channels".
D000818:Animals; D001369:Axons / Q000187:drug effects* / Q000378:metabolism; D001665:Binding Sites; D049832:Decapodiformes; D004553:Electric Conductivity; D007700:Kinetics; D008959:Models, Neurological; D011188:Potassium / Q000378:metabolism*; D011725:Pyridines / Q000494:pharmacology*
D011725:Pyridines; D011188:Potassium
Medèle d'action de la 4-aminopyridine au niveau des "cannaux" potassium de l'axone géant de calmar (Logigo forbesi L)