[Pathogenetic mechanisms of tick-borne encephalitis].
The main cause of progressive forms of tickborne encephalitis is a prolonged persistence of certain viral strains in the brain. Although there are no virals with a selective capability to lead only to an acute or chronic encephalitis, nevertheless in the epidemiological process there is a selection of virals capable of bringing on chronic forms of the disease. In cases of an incapacity of immunological factors bor a defence during the initial phase of the infectious process there may be prerequisites to a fixation of the virals in the brain and a chronic development of the neuroinfections. It is necessary to differentiate active neuroinfectious processes due to persistent virals and postencephalitic reparative-dystrophical syndromes. This permits to avoid a hyperdiagnosis and more reasonably select therapeutical measures in the evaluation of their effectivity.
D000818:Animals; D001921:Brain / Q000382:microbiology* / Q000473:pathology; D004669:Encephalitis Viruses, Tick-Borne / Q000302:isolation & purification*; D004675:Encephalitis, Tick-Borne / Q000209:etiology* / Q000382:microbiology; D005911:Gliosis / Q000382:microbiology; D000882:Haplorhini
Nekotorye patogeneticheskie mekhanizmy progredientnykh form kleshchevogo éntsefalita