title: On the dose response in B. subtilis transfection: involvement of aggregates in phi 29 transfection.
abstract: Transfection with phi 29 DNA is predominantly caused by multimolecular, protease-sensitive aggregates of DNA. A minority of transfecting DNA molecules having properties of unit-length phi 29 genome molecules show a quadratic dose response in transfection.
mesh_terms: D001412:Bacillus subtilis / Q000235:genetics*; D001435:Bacteriophages / Q000235:genetics*; D004279:DNA, Viral / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000494:pharmacology; D014162:Transfection
chemical_list: D004279:DNA, Viral; D010447:Peptide Hydrolases