title: [Effect of calcium ions on channels for entrance and exit of ionic currents in the membranes of mollusk neurons].
abstract: A newly developed method of internal dialysis was applied together with the voltage clamp method to the isolated neurons of molluscs Helix pomatia and Limnea stagnalis. Effect of Ca on the Ca inward and K delayed outward currents was investigated. Removal of Ca from the external medium was equivalent to 25-35 mV hyperpolarization of the membrane. Internal Ca in concentrations up to 3.5-10-(7)M caused insignificant depression of K outward current. 5.7-10-(8)M of internal Ca completely blocked Ca inward current. Ca-chelating agents applied either internally or externally caused an appearance of Na inward current transferred through the Ca channels.
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism / Q000494:pharmacology*; D002462:Cell Membrane / Q000378:metabolism; D004533:Egtazic Acid / Q000494:pharmacology; D004563:Electrochemistry; D006372:Helix, Snails; D008195:Lymnaea; D008564:Membrane Potentials / Q000187:drug effects*; D009474:Neurons / Q000187:drug effects*; D012964:Sodium / Q000378:metabolism
chemical_list: D004533:Egtazic Acid; D012964:Sodium; D002118:Calcium
vernacular_title: Deĭstvie ionov kal'tsiia na kanaly vkhodiashchikh i vykhodiashchikh ionnykh tokov v membrane neĭronov molliuskov