Immunological studies in neonates with spina bifida.
Fifteen neonates with spina bifida were investigated prior to surgery for T and B lymphocytes subpopulations and mitogen responsiveness to PHA. Results were compared to similar studies in 30 normal healthy neonates. The mean percentage of T-lymphocyes in spina bifida patients was 44.6% compared to 48.9% in normal neonates. A normal dose response to PHA was obtained in all patients. These results suggest no impairment of lymphocyte function in neonates born with spina bifida.
D001402:B-Lymphocytes / Q000276:immunology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007958:Leukocyte Count; D008297:Male; D008934:Mitogens / Q000276:immunology; D010835:Phytohemagglutinins / Q000276:immunology; D016136:Spina Bifida Occulta / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D008934:Mitogens; D010835:Phytohemagglutinins