Effect in vitro of ioglycamide on blood proteins and paraproteins.
No modification of plasma or serum viscosity was observed after in vitro addition of ioglycamide in a series of 160 healthy subjects and 1 467 patients including 33 cases of IgM paraproteinemia, 20 with Waldenström's disease. The labelled contrast medium never bound to paraproteins. These results are contradictory to the statements in the literature, that plasma gel formation occurs in Waldenström's disease.
D001798:Blood Proteins; D001809:Blood Viscosity / Q000187:drug effects; D006801:Humans; D007075:Immunoglobulin M; D007463:Iodobenzoates; D007471:Ioglycamic Acid; D010265:Paraproteinemias / Q000097:blood; D010266:Paraproteins; D011485:Protein Binding; D008258:Waldenstrom Macroglobulinemia / Q000097:blood
D001798:Blood Proteins; D007075:Immunoglobulin M; D007463:Iodobenzoates; D010266:Paraproteins; D007471:Ioglycamic Acid