Regulation of human hemopoietic stem cell proliferation by syngeneic thymus-derived lymphocytes.
Viable T lymphocytes stimulate the proliferation of human syngeneic hemopoietic stem cells, but not influence their differentiation. The biological significance of this activity is discussed and its possible physiological role in the regulation of hemopoiesis is considered.
D001772:Blood Cell Count; D002455:Cell Division; D006410:Hematopoiesis; D006412:Hematopoietic Stem Cells / Q000502:physiology*; D006801:Humans; D013601:T-Lymphocytes / Q000502:physiology*