title: [Postpartum contraception: effect of lynestrenol during the lactation period (author's transl)].
abstract: 167 women were treated with 0.5 mg lynestrenol/day for a period of 8-32 weeks immediately postpartum. The lactation periods of 67 of the women were observed during the stay in hospital (maximum 7 days) in comparison with a control group (n = 20) of untreated women in the puerperium. There was no quantitative difference in milk production between the lynestrenol-treated women and the control group. In order to exclude a possible thromboembolic effect the lynestrenol the thrombocyte aggregation was determined in all women at 4-weekly intervals as a measure of a thrombotic tendency. During the entire period of the investigation the mean PAT rating remained between I and II. Among the clinical parameters a raised amenorrhea rate of 21% and a larger proportion (39%) of breakthrough bleedings were notable. The responded easily to treatment.
mesh_terms: D000293:Adolescent; D000328:Adult; D002582:Cervix Mucus / Q000187:drug effects / Q000378:metabolism; D005260:Female; D006801:Humans; D007774:Lactation / Q000187:drug effects*; D008234:Lynestrenol / Q000009:adverse effects / Q000378:metabolism / Q000494:pharmacology*; D008599:Menstruation Disturbances / Q000139:chemically induced; D008895:Milk, Human / Q000378:metabolism; D010974:Platelet Aggregation / Q000187:drug effects; D049590:Postpartum Period / Q000187:drug effects*; D011247:Pregnancy
chemical_list: D008234:Lynestrenol
vernacular_title: Kontrazeption post partum: Beeinflussung der Stillperiode durch Lynestrenol.