[The effect of antacids on stress-induced lesions of the gastric mucosa in the piglet (author's transl)].
After administration of antacids, gastric stress lesions due to hemorrhagic shock appear in the pig stomach quicker and more markedly than in animals which have been similarly treated with an indifferent substance or not at all. However, once treated, the administration of antacids seems to favor the healing of mucosal lesions after the end of the stress. At the same time it was observed that after administration of antacids in hemorrhagic shock, the serum gastrin level rises and does not remain  constant, as in the control group. An attempt is made to explain the favorable effect of antacids on the genesis of hemorrhagic stress lesions in the pig's stomach through this observation.
D000818:Animals; D000863:Antacids / Q000009:adverse effects / Q000494:pharmacology*; D004195:Disease Models, Animal; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects* / Q000473:pathology; D005755:Gastrins / Q000097:blood; D006471:Gastrointestinal Hemorrhage / Q000473:pathology; D008297:Male; D012771:Shock, Hemorrhagic / Q000150:complications / Q000473:pathology; D013272:Stomach Diseases / Q000209:etiology; D013276:Stomach Ulcer / Q000209:etiology; D013312:Stress, Physiological / Q000150:complications; D013552:Swine; D013997:Time Factors
D000863:Antacids; D005755:Gastrins
Uber der Einfluss von Antazida auf stressinduzierte Magenschleimhautläsionen beim Ferkel