title: [Active therapeutic exercises in combination with vasoactive drug in intermittent claudication (author's transl)].
abstract: Earlier investigations have shown that the success of physiotherapeutic exercises in peripheral arterial circulatory disturbances in stage II (Fontaine) can be increased by additional administration of "vasoactive" substances. In the present double-blind study, therefore, 102 outpatients were treated with magnesium nicotinate-magnesium dehydrocholate or a placebo in addition to basic physical therapy. The drug collective (n = 50) showed an increase in walking distance of 24.1% compared with the placebo group (n = 52). Also, in respect to the success rate, the drug collective did better, which, however, may have been due to the unequal distribution of the prognosis factors. Yet it may be concluded that the physiotherapeutic exercises can be effectively supported by the drug tested.
mesh_terms: D000368:Aged; D002986:Clinical Trials as Topic; D003685:Dehydrocholic Acid / Q000627:therapeutic use*; D004311:Double-Blind Method; D004341:Drug Evaluation; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D007383:Intermittent Claudication / Q000188:drug therapy / Q000628:therapy*; D008274:Magnesium / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009539:Nicotinic Acids / Q000627:therapeutic use*; D010919:Placebos
chemical_list: D009539:Nicotinic Acids; D010919:Placebos; D008274:Magnesium; D003685:Dehydrocholic Acid
vernacular_title: Kombination aktiver Ubungsbehandlung mit einem vasoaktiven Pharmakon bei Claudicatio intermittens.