title: Hydroxylation of tyrosine by plant peroxidase and mushroom tyrosinase, with and without hydrazine, to retard the oxidation of dopa.
abstract: Tyrosine was oxidized to dopa by horseradish peroxidase and mushroom tyrosinase. The first step of hydroxylation of tyrosine in the synthesis of melanin was demonstrated by isolation of dopa from the reaction mixture using hydrazine as a selective retardant.
mesh_terms: D004156:Catechol Oxidase / Q000378:metabolism*; D004295:Dihydroxyphenylalanine / Q000096:biosynthesis*; D006735:Horseradish Peroxidase / Q000378:metabolism*; D006834:Hydrazines / Q000494:pharmacology; D006900:Hydroxylation; D014442:Monophenol Monooxygenase / Q000378:metabolism*; D010084:Oxidation-Reduction; D010544:Peroxidases / Q000378:metabolism*; D014443:Tyrosine / Q000378:metabolism
chemical_list: D006834:Hydrazines; D014443:Tyrosine; D004295:Dihydroxyphenylalanine; D004156:Catechol Oxidase; D006735:Horseradish Peroxidase; D010544:Peroxidases; D014442:Monophenol Monooxygenase