On the relationship between glycerophosphoglycolipids and lipoteichoic acids of gram-positive bacteria. III. Di(glycerophospho)-acylkojibiosyldiacylglycerol and related compounds from Streptococcus lactis NCDO 712.
1. Streptococcus lactis NCDO 712 contains at lease three unusually polar glycerophosphoglycolipids. One of them was composed of D-glucose, glycerol, fatty acid ester, and phosphorus in the molar ratio of approx. 2 : 3 : 3 : 2. The structure was established as 1,2-di-O-acyl-3-O-[6-(sn-glycero-1-phospho-3-sn-glycero-1-phospho)-alpha-D-glucopyranosyl-(1 leads to 2)-(6-O-acyl-alpha-D-glucopyranosyl)]-glycerol. 2. The second glycerophosphoglycolipid was shown to have the same core structure but is lacking the carbohydrate-linked fatty acid. The third glycero-phosphoglycolipid is a glycosylated derivative of the first one bearing an alpha-galactosyl residue at position 2 of the inner glycolipid-linked glycerophosphate moiety. 3. These novel phosphoglycolipids are considered to be the so far missing link between simple glycerophosphoglycolipids and lipoteichoic acids of Gram-positive bacteria.
D000468:Alkalies; D055598:Chemical Phenomena; D002621:Chemistry; D004075:Diglycerides / Q000378:metabolism; D006017:Glycolipids / Q000378:metabolism*; D006868:Hydrolysis; D013294:Lactococcus lactis / Q000378:metabolism*; D013058:Mass Spectrometry; D010712:Phosphatidic Acids / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism*; D013682:Teichoic Acids / Q000378:metabolism*
D000468:Alkalies; D004075:Diglycerides; D006017:Glycolipids; D010712:Phosphatidic Acids; D010743:Phospholipids; D013682:Teichoic Acids