Double controlled comparison of IDU and trifluorothymidine in thirty-three patients with superficial herpetic keratitis.
Thirty-three patients were followed in a double controlled study to test the efficacy of IDU and TFT on superficial epithelial herpes simplex virus infection. Sixteen received TFT and 17, IDU. There were four failures in patients on IDU therapy and no failures in the 16 patients using TFT. These results indicate a trend for greater efficacy of TFT than IDU. In those patients who healed with IDU and with TFT, there was no difference in the number of days to heal in each group.
D000208:Acute Disease; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007065:Idoxuridine / Q000627:therapeutic use*; D007635:Keratitis, Dendritic / Q000188:drug therapy*; D008297:Male; D013936:Thymidine / Q000031:analogs & derivatives*; D014271:Trifluridine / Q000627:therapeutic use*
D007065:Idoxuridine; D014271:Trifluridine; D013936:Thymidine