Biochemical and pharmacological effects of the fermentation-derived antitumor agent, (alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125).
D015092:3-Deazauridine / Q000494:pharmacology; D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D004351:Drug Resistance; D005260:Female; D005998:Glycine / Q000031:analogs & derivatives* / Q000494:pharmacology; D007555:Isoxazoles / Q000494:pharmacology* / Q000633:toxicity; D007928:Lethal Dose 50; D007939:Leukemia L1210 / Q000188:drug therapy* / Q000378:metabolism; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009711:Nucleotides / Q000378:metabolism; D010080:Oxazoles / Q000494:pharmacology*; D012737:Sex Factors
D000903:Antibiotics, Antineoplastic; D007555:Isoxazoles; D009711:Nucleotides; D010080:Oxazoles; D015092:3-Deazauridine; D005998:Glycine