title: Variable substructure in the secondary constriction of the human chromosome 1.
abstract: The secondary constriction in human chromosome 1 consists of a proximal segment stained by the GC-specific fluorochrome mithramycin and a distal segment stained by such fluorochromes as DAPI or DIPI, which show enhanced fluorescence intensities in AT-rich regions of the chromosomes. A study involving 21 individuals revealed that both parts are independently involved in length variability. In two cases, two GC-rich regions separated by an AT-rich segment and an additional distal AT-rich part were found.
mesh_terms: D001483:Base Sequence; D002871:Chromosome Banding; D002900:Chromosomes, Human, 1-3 / Q000648:ultrastructure*; D004247:DNA / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D004247:DNA