Goniodysgenesis in exfoliation glaucoma.
According to our material the exfoliation glaucoma can be regarded as the result of an interplay of at least two different pathologic conditions: a primary genetic goniodysgenesis creating a relative block to the outflow, and a probable vasculopathy in the iris. Subsequent degeneration of the iris will lead to a liberation of pigment and debris, i.e., the exfoliation syndrome, eventually causing obliteration of the outflow pathways.
D000368:Aged; D005123:Eye / Q000473:pathology; D005124:Eye Abnormalities; D005260:Female; D005901:Glaucoma / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D010375:Pedigree; D014129:Trabecular Meshwork / Q000473:pathology; D014603:Uveal Diseases / Q000150:complications* / Q000175:diagnosis