Effect of chronic oral methadone treatment on the growth of maturing monkeys.
Three male rhesus monkeys drank methadone hydrochloride (1.0-2.5 mg/kg/day) in Tang orange drink from age two to four years. Their rate of body weight gain was faster than that found by other experimenters. In a second study one male monkey drank 2.0 mg/kg/day methadone while two others drank only Tang from age 21/2 to 31/2 years. The rate of body weight gain was identical for the three monkeys, and was the same as that found in the previous study. The apparent augmentation of body weight gain in the first study was probably due to inter-laboratory differences in housing and feeding conditions.
D000367:Age Factors; D000818:Animals; D001724:Birth Weight; D001835:Body Weight / Q000187:drug effects*; D000882:Haplorhini; D006801:Humans; D008251:Macaca / Q000254:growth & development*; D008253:Macaca mulatta / Q000254:growth & development*; D008297:Male; D008691:Methadone / Q000494:pharmacology*; D008954:Models, Biological
D008691:Methadone