[Some aspects of biliary secretion in four species of primates (P. mandrillus, P. papio, E. patas and M. mulatta) (author's transl)].
Effect of several factors on flow and composition of bile of four species of Primates has been studied. Flow of bile widely varied. The smallest flow was found in E. patas and the greatest in P. mandrillus; P. papio and M. mulatta flows were intermediate. Cholic acid concentration in basal bile was small. Electrolites Na+, K+ and C1- were found in concentration close to its plasmatic values. In all four species, interruption of enterohepatic circulation of bile salt, induced a clear decrease in basal flow. Secretin injection (1 U/kg) induced flow increases in P. mandrillus. In M. mulatta and E. patas relationship between logarithm of secretin doses and biliary responses seems to occur. Cholecistokinine-Pancreozimine (2 U/kg) produced in P papio espectacular increases of flow and bile salts concentration with concomitant chloride decreases. Vagal stimulation gave no clear results, although vagal section and use of parasimpathicolitic drugs induced bile flow decreases that show a possible tonic vagal action on extrahepathic biliary tree.
D000818:Animals; D001646:Bile / Q000378:metabolism* / Q000502:physiology; D001647:Bile Acids and Salts / Q000032:analysis; D001652:Bile Ducts / Q000502:physiology; D002766:Cholecystokinin / Q000494:pharmacology*; D004901:Erythrocebus patas; D000882:Haplorhini; D008251:Macaca; D008297:Male; D010215:Papio; D011323:Primates / Q000502:physiology*; D012633:Secretin / Q000494:pharmacology; D012636:Secretory Rate / Q000187:drug effects; D013268:Stimulation, Chemical; D014630:Vagus Nerve / Q000502:physiology
D001647:Bile Acids and Salts; D012633:Secretin; D002766:Cholecystokinin
Algunos aspectos de la secreción biliar en cuatro especies de primates (P mandrillus, P. papio, M. mulatta, E. patas)