Immunological studies of eosinophilic gastro-enteritis and treatment with disodium cromoglycate and beclomethasone dipropionate.
A 45-year-old woman with intestinal malabsorption due to eosinophilic gastro-enteritis was found to have markedly fluctuating total serum IgE levels with a positive intradermal skin test and a positive radio-allergosorbent test to milk antigen. No organ-specific or non-organ-specific auto-antibodies were detected in the patient's serum, and her complement profile was normal. Low doses of disodium cromoglycate failed to improve intestinal absorption, whereas a 16-day course of a corticosteroid, beclomethasone dipropionate 3 mg daily, improved D-xylose and carotene absorption without suppressing the hypothalamic-pituitary-adrenal axis.
D001507:Beclomethasone / Q000627:therapeutic use*; D004205:Cromolyn Sodium / Q000627:therapeutic use*; D004804:Eosinophils; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications; D005759:Gastroenteritis / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008875:Middle Aged
D007073:Immunoglobulin E; D001507:Beclomethasone; D004205:Cromolyn Sodium