Changes in the ultrastructure of satellite cells of slow loris in tricresylphosphate poisoning.
Toxic reaction of satellite cells from posterior root ganglia of slow loris in TCP poisoning is described. The satellite cells in experimental animals show a marked increase in the rough ER, Golgi complex, microvesicles and filaments. Furthermore there is also an increase in the number of dense bodies and mitochondrial density in these cells. The significance of these changes are discussed and it is concluded that in TCP poisoning not only the neurons but the supporting cells are also affected.
D000818:Animals; D003408:Cresols / Q000506:poisoning*; D005727:Ganglia, Spinal / Q000187:drug effects* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009417:Nerve Tissue / Q000648:ultrastructure; D012183:Retrograde Degeneration; D011443:Strepsirhini; D014317:Tritolyl Phosphates / Q000506:poisoning*
D003408:Cresols; D014317:Tritolyl Phosphates