title: 25-hydroxycholecalciferol: high affinity substrate for hepatic cytochrome P-450.
mesh_terms: D000633:Aminopyrine N-Demethylase / Q000037:antagonists & inhibitors; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D004097:Dihydrotachysterol / Q000378:metabolism; D004789:Enzyme Activation; D004872:Ergocalciferols / Q000378:metabolism; D006887:Hydroxycholecalciferols / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism*; D009251:NADPH-Ferrihemoprotein Reductase / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology; D011485:Protein Binding; D051381:Rats; D014808:Vitamin D Deficiency / Q000378:metabolism
chemical_list: D004872:Ergocalciferols; D006887:Hydroxycholecalciferols; D003577:Cytochrome P-450 Enzyme System; D000633:Aminopyrine N-Demethylase; D009251:NADPH-Ferrihemoprotein Reductase; D004097:Dihydrotachysterol; D010634:Phenobarbital