[Effect of a parenterally administered casein hydrolysate on the secretory activity of the stomach with different degrees of gastric gland denervation].
Experiments carried out on dogs helped ascertain the casein hydrolysate capable of provoking gastric secretion both with retained gastric innervation and without preservation of the vagal and sympathetic innervation. As this been shown earlier the effect of nitrous substances on the gastric secretion is realized mainly through the agency of the nervous mechanism. The observed secretion in dogs with denervated isolated pouches, however, occuring in response to administration of casein hydrolysate may be explained by mobilization of gastrin under the effect of nervous impulses and its action on the gastric glands. This assumption has been confirmed by tests carried out with the inhibitorglycomacropeptide which inhibits mainly the action of gastrin on the gastric glands.
D000818:Animals; D002364:Caseins; D004285:Dogs; D005753:Gastric Mucosa / Q000294:innervation / Q000378:metabolism*; D006020:Glycopeptides / Q000494:pharmacology; D010288:Parenteral Nutrition; D011492:Protein Hydrolysates / Q000008:administration & dosage; D013562:Sympathectomy; D014628:Vagotomy
D002364:Caseins; D006020:Glycopeptides; D011492:Protein Hydrolysates
Deĭstvie parenteral'no vvedennogo gidrolizata kazeina na sekretornuiu deiatel'nost' zheludka pri raznoĭ stepeni denervatsii zheludochnykh zhelez.