[Correction of nitrogen metabolism in rats with toxic hepatitis by parenteral administration of an amino acid mixture].
The nitrogen metabolism in rats with toxic affection of the liver caused by administration of CCl4 was studied as affected by the amino acid mixture moriamine S-2. It is established that with toxic hepatitis the nitrogen metabolism is sharply disturbed, especially during protein deficiency. The following evidences for this fact: a rise in the depth of the nitrogen negative balance, an increase in the intensity of amine nitrogen and ammonia excretion with urea as well as an increase in the amount of amine nitrogen in blood and tissues with a simultaneous decrease in the content of protein. The parenteral administration of the amino acid mixture for eight days to the animals with a toxic affection of the liver is more effective when nitrogen preparation is combined with the group B vitamin, vitamin C, insulin, nerobolyl and sirepar.
D000596:Amino Acids / Q000008:administration & dosage*; D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000150:complications* / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications* / Q000188:drug therapy; D005260:Female; D007279:Injections, Subcutaneous; D008099:Liver / Q000032:analysis; D008297:Male; D009132:Muscles / Q000032:analysis; D009206:Myocardium / Q000032:analysis; D009584:Nitrogen / Q000032:analysis; D011488:Protein Deficiency / Q000150:complications* / Q000188:drug therapy; D051381:Rats
D000596:Amino Acids; D009584:Nitrogen
Korrektsii azotistogo obmena parenteral'no vvedennoĭ aminokislotnoĭ smes'iu pri toksicheskom gepatite u krys.