[Fibrinogen Quebec I and Quebec II: two new families of dysfibrinogenemia (author's transl)].
Two new families of congenital dysfibrinogenemia originating from French Canada are reported. The dysfibrinogenemia in the first family is characterized by an abnormal aggregation of the fibrin monomers; the defect in the second family is due to a faulty release of fibrinopeptides during the proteolytic phase of the thrombin-fibrinogen reaction.
D001778:Blood Coagulation Disorders / Q000151:congenital / Q000235:genetics*; D005260:Female; D005337:Fibrin / Q000378:metabolism; D005340:Fibrinogen; D006474:Hemorrhagic Disorders / Q000235:genetics; D006801:Humans; D008297:Male
D005337:Fibrin; D005340:Fibrinogen
Fibrinogènes Québec I et Québec II: deux nouvelles familles de dysfibrinogénémie.