title: [Effect of single impulses on cochlear microphone potentials of the guinea-pig cochlea].
abstract: The influence of highly intensive single impulses on the cochlea of guinea pig was studied in an acute experiment. Very short impulses of less than or equal to 0.1 ms duration were produced by a sparknoise generator. The cochlear microphonics (CM) to a test stimulus (sinus tone, 3150 Hz) were recorded from the round window and measured prior to, during, and following impulse treatment. During the impulse treatment, the greatest amplitude reduction of CM occurred after the first impulse, while the further impulses caused a decreasing reduction. At first the number of impulses was varied: 1, 3, and 5 impulses were applied at intervals of 15 s each, at an impulse sound level of 164 dB sound pressure level re. 0.002 mubar (SPL). After these impulse treatments, in all cases a continual decrease of CM amplitudes up to a constant end value without recovery was found within a 2-hrs period of observation. The height of the end value depends on the number of impulses applied. Subsequently, at an exposure to 5 impluses the impulse sound level was stepwise reduced (164, 153, 144, 139 and 133 dB SPL). Again, a characteristic decrease of CM amplitudes was observed during the 2-hrs period of observation. The height of the end value is now dependent on the impluse sound level. Impulses of 164, 153 and 144 dB SPL cause a strong decrease of CM while the effect of impulses of 139 and 133 dB SPL is distinctly lower.
mesh_terms: D000161:Acoustic Stimulation; D000200:Action Potentials; D000818:Animals; D001309:Auditory Threshold; D003051:Cochlea / Q000502:physiology*; D006168:Guinea Pigs; D000882:Haplorhini; D008253:Macaca mulatta; D009991:Oscillometry / Q000379:methods
vernacular_title: Die Wirkung von Einzelimpulsen auf das Mikropotential der Meerschweinchenocochlea.