title: Operative management of radiation injuries of the intestinal tract.
abstract: A review of forty cases of radiation-induced gastrointestinal injuries is presented. Based on this experience and reports in the literature, preoperative management and operative technics are discussed. The increased risk of radiation bowel injury is recognized in patients who have had previous operations. Preradiation contrast studies are advised to identify trapped loops of intestine in the pelvis. Small bowel resection is recommended with localized segments of disease. Bypass operations are preferable to avoid any extensive dissections. Bypass operations have anastomotic dehiscence rates similar to those of resections. Proctocolitis is usually managed by diverting colostomy, with resection in a few favorable cases or with treatment failures. Most rectovaginal fistulas are managed by permanent colostomy. Small bowel fistulas are best treated by bypass with partial or total exclusion rather than by primary resection. Vigorous preoperative and postoperative nutritional support and evaluation are vital because of the poor healing qualities of irradiated bowel. Multiple operative procedures should be anticipated because the natural history of radiation bowel injury is slowly progressive.
mesh_terms: D000368:Aged; D003092:Colitis / Q000209:etiology / Q000601:surgery; D003108:Colonic Diseases / Q000209:etiology / Q000601:surgery; D004751:Enteritis / Q000209:etiology / Q000601:surgery; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000209:etiology* / Q000601:surgery; D007415:Intestinal Obstruction / Q000209:etiology / Q000601:surgery; D007416:Intestinal Perforation / Q000209:etiology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011349:Proctitis / Q000209:etiology / Q000601:surgery; D011832:Radiation Injuries / Q000601:surgery*; D011878:Radiotherapy / Q000009:adverse effects*; D012003:Rectal Fistula / Q000209:etiology / Q000601:surgery; D012006:Rectovaginal Fistula / Q000209:etiology / Q000601:surgery