[Electroclinical correlations during anticonvulsive therapy of status epilepticus and chronic focal epilepsies using clonazepam].
Clonazepam was used in 22 instances of status epilepticus by intravenous route with particularly good results. Severe etiologies in status were common. Therapy of partial and secondarily generalized convulsion is favoured. 18 patients with epilepsies of similar classification were treated by long term oral administration with inconstant results. Spatio-temporal and dose related profiles of convulsive and electroencephalographic desactivation are demonstrated. Signs of secondary generalisation were abolished first whereas focal signs turned out more resistent proved by repeated EEG recordings. Hypnotic effect as constituent or not in parenteral status therapy is discussed.
D000293:Adolescent; D000328:Adult; D001570:Benzodiazepinones / Q000627:therapeutic use*; D001921:Brain / Q000503:physiopathology; D002908:Chronic Disease; D002998:Clonazepam / Q000627:therapeutic use*; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D013226:Status Epilepticus / Q000188:drug therapy* / Q000503:physiopathology
D001570:Benzodiazepinones; D002998:Clonazepam
Elektroklinische Korrelationen während der antikonvulsiven Behandlung des Status epilepticus und chronischer Epilepsien fokaler Genese mit Clonazepam.