[Interaction of two isomers, N-nitrosomethylphenylamine, N-nitroso derivative, and p-nitrosomethylaniline with microorganisms].
There exists a relationship between the chemical structure C--NO or N--NO and biological effects. p-nitrosomethylaniline, a C-nitroso compound, in contrast to its isomer, N-nitrosomethylphenylamine, a N-nitroso derivate, shows a marked action against microoganisms and is, alone, reduced enzymatically.
D000814:Aniline Compounds / Q000494:pharmacology*; D000818:Animals; D001419:Bacteria / Q000187:drug effects*; D007536:Isomerism; D051379:Mice; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism; D009602:Nitrosamines / Q000494:pharmacology*; D009603:Nitroso Compounds / Q000494:pharmacology
D000814:Aniline Compounds; D009602:Nitrosamines; D009603:Nitroso Compounds; D009247:NADH, NADPH Oxidoreductases
Interrelations de deux isomères, la n-nitrosométhylphénylamine dérivé n-nitrosé et la p-nitrosométhylaniline, avec les microorganismes.