[Action of biotin-pyridoxine complex on the development of experimental atherosclerosis].
Investigations were conducted in two series of tests on 40 rabbits. In the first series a selection of the optimal dose of the vitamins was made and in the II series the action of the optimal dose of the biotin-pyridoxine complex was studied. Each test series included 2 control groups of the animals. The biotin-pyridoxine complex (in doses of 80 gamma and 3.2 mg per 1 kg of the body mass) was shown to exert an inhibitory action on the development of experimental atherosclerosis.
D000818:Animals; D001161:Arteriosclerosis / Q000188:drug therapy* / Q000378:metabolism; D001710:Biotin / Q000627:therapeutic use*; D001777:Blood Coagulation / Q000187:drug effects; D004036:Diet, Atherogenic; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D050356:Lipid Metabolism; D008297:Male; D011736:Pyridoxine / Q000627:therapeutic use*; D011817:Rabbits; D013997:Time Factors
D004338:Drug Combinations; D001710:Biotin; D011736:Pyridoxine
Deĭstvie kompleksa biotin-piridoksin na razvitie éksperimental'nogo ateroskleroza.