Cytopathic effect and plaque formation by arboviruses in a continuous cell line (XTC-2) from the toad Xenopus laevis.
Forty-six arboviruses were tested for c.p.e. and/or plaque formation in an amphibian cell line. C.p.e. was observed with a high proportion of the viruses tested. Comparative plaque assay, in the XTC-2 cells at 28 degrees C and Vero cells at 37 degrees C, suggests that these systems are comparable in sensitivity and susceptibility to infection. Practical uses of this cell line are discussed.
D000818:Animals; D001103:Arboviruses / Q000254:growth & development*; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D000882:Haplorhini; D010948:Viral Plaque Assay; D014779:Virus Replication; D014981:Xenopus