Effects and side effects of radiosynovectomy with Yttrium 90 on rheumatic joint cartilage.
8 and 12 weeks after Synovectomy with Yttrium 90, cartilage specimens from the femoral condyle of 8 patients with R.A. were examined. Cellular and matrix damage could be detected. Intracellular particles containing Circonium, an Yttrium decay-product could be found using microprobe X-ray analysis. This was verified in experimentally induced arthritis in the rat.
D000818:Animals; D001172:Arthritis, Rheumatoid / Q000473:pathology / Q000532:radiotherapy*; D002358:Cartilage, Articular / Q000473:pathology / Q000528:radiation effects*; D006801:Humans; D007270:Injections, Intra-Articular; D051381:Rats; D015021:Yttrium Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*
D015021:Yttrium Radioisotopes