[Retrospective study of 99 cases of ovarian carcinoma, stages I to IV].
A retrospective study on the survival of 99 patients with ovarian carcinoma stages I-IV has been conducted. A bad prognosis for early stages is emphasized. 38 of the 64 patients treated by chemotherapy presented an objective therapeutic response: 24 cases showed complete or partial remission of a duration between 4 to 26 months, while 14 cases showed no change or progressive disease. The effects of chemotherapy on survival have been statistically analyzed for these 38 cases and have shown a longer survival for responders. These results suggest that the use of chemotherapy as an adjuvant to surgery in ovarian cancer deserves further investigation.
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000401:mortality / Q000473:pathology*; D002699:Chlorambucil / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000473:pathology*; D012189:Retrospective Studies; D013852:Thiotepa / Q000627:therapeutic use
D002699:Chlorambucil; D003520:Cyclophosphamide; D013852:Thiotepa
Etude rétrospective de 99 cas de carcinomes ovariens, stades I à IV.