Rat liver post-microsomal D-T diaphorase: activation of the enzymes by two carcinogens.
The effects of two carcinogens (N-acetylaminofluorene and 7, 12-dimethylbenz(a)anthracene) on the rat liver soluble D-T diaphorase are reported in this communication. The activity of the enzyme is increased in 24 hours by both compounds tested in this study.
D015073:2-Acetylaminofluorene / Q000494:pharmacology; D015127:9,10-Dimethyl-1,2-benzanthracene / Q000494:pharmacology; D000818:Animals; D002273:Carcinogens / Q000494:pharmacology*; D004789:Enzyme Activation; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism*; D011808:Quinone Reductases / Q000378:metabolism*; D051381:Rats
D002273:Carcinogens; D015127:9,10-Dimethyl-1,2-benzanthracene; D015073:2-Acetylaminofluorene; D009247:NADH, NADPH Oxidoreductases; D011808:Quinone Reductases