A gradual score to evaluate the climbing behaviour elicited by apomorphine in mice.
Mice treated with apomorphine tend to adopt a vertical position in a stereotyped manner. A quantal evaluation of this behaviour, taking into account its frequency and duration, leads to a biphasic dose-response curve that reveals opposite actions of the dopamine agonist.
D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D001519:Behavior / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008297:Male; D051379:Mice; D011954:Receptors, Dopamine / Q000187:drug effects; D013239:Stereotyped Behavior / Q000187:drug effects*; D013997:Time Factors
D011954:Receptors, Dopamine; D001058:Apomorphine