Oxygenation of the cerebral and coronary circulation with right axillary artery perfusion during venoarterial bypass in primates.
The effectiveness of right axillary artery perform in delivering oxygenated blood to the cerebral and coronary circulation during venoarterial bypass in primates was studied. Both right and left common carotid flow measurements and arterial gas measurements revealed high flows and elevated PO2 levels. Incomplete mixing in the ascending aorta was observed from cineangiograms taken at various pump oxygenator flows in 1 animal. The results demonstrated that the brain receives excellent oxygenation at all bypass levels. However, the coronary circulation is perfused primarily by blood ejected from the left ventricle and receives only minimal contribution of well-oxygenated blood from the pump oxygenator circuit. Therefore, the heart may suffer prolonged hypoxemia during long-term venoarterial bypass for acute respiratory insufficiency.
D000818:Animals; D001013:Aorta, Thoracic / Q000502:physiology; D001366:Axillary Artery / Q000502:physiology; D002302:Cardiac Output; D002339:Carotid Arteries / Q000502:physiology; D002404:Catheterization; D002496:Central Venous Pressure; D002560:Cerebrovascular Circulation; D003326:Coronary Circulation; D005112:Extracorporeal Circulation; D005268:Femoral Vein; D000882:Haplorhini; D010100:Oxygen / Q000097:blood; D010215:Papio
D010100:Oxygen