[Hemodynamics in swine treated with PGI 2].
The hemodynamic response of pig perfused by PGI2 (2 micrograms/kg/mm/4 min) has been studied before and after vagosympathectomy. Prostacyclin produces hypotension, which depends to an reduction of total peripheral resistances, without cardiac involvement. A venous dilatation is also present with reduction of preload and of systolic volume. The authors conclude assessing that prostaciclyn act by peripheral mechanism.
D000818:Animals; D011464:Epoprostenol / Q000494:pharmacology*; D006439:Hemodynamics / Q000187:drug effects*; D007022:Hypotension / Q000139:chemically induced; D011453:Prostaglandins / Q000494:pharmacology*; D013552:Swine
D011453:Prostaglandins; D011464:Epoprostenol
Emodinamica nel maiale trattato con PGI2.