Drug kinetics in protein energy malnutrition.
Potential problems of drug metabolism in human protein energy malnutrition (PEM) are reviewed in the light of the pathophysiological changes seen in PEM. Data derived from human studies and animal experiments are discussed, and a plea is made for further research in this area.
D000818:Animals; D001646:Bile / Q000378:metabolism; D002648:Child; D006801:Humans; D007223:Infant; D007408:Intestinal Absorption; D007668:Kidney / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011485:Protein Binding; D011502:Protein-Energy Malnutrition / Q000378:metabolism*; D051381:Rats
D004364:Pharmaceutical Preparations