Metabolic reduction of 4-nitroquinoline N-oxide and other radical-producing drugs to oxygen-reactive intermediates.
D015112:4-Nitroquinoline-1-oxide / Q000378:metabolism* / Q000494:pharmacology; D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003580:Cytochromes / Q000378:metabolism; D004579:Electron Transport / Q000187:drug effects; D005609:Free Radicals; D005947:Glucose / Q000378:metabolism; D006861:Hydrogen Peroxide / Q000378:metabolism; D066298:In Vitro Techniques; D008861:Microsomes / Q000378:metabolism; D009581:Nitrofurans / Q000378:metabolism* / Q000494:pharmacology; D009600:Nitroquinolines / Q000378:metabolism*; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects; D014812:Vitamin K / Q000378:metabolism* / Q000494:pharmacology
D003580:Cytochromes; D005609:Free Radicals; D009581:Nitrofurans; D009600:Nitroquinolines; D014812:Vitamin K; D015112:4-Nitroquinoline-1-oxide; D006861:Hydrogen Peroxide; D005947:Glucose