Reagin-like activity of serum in human peridonotal disease.
The serum from patients with periodontitis produced a passive cutaneous anaphylaxis reaction in monkeys when tested against subgingival plaque. This detection of reaginic antibodies shows that patients with periodontitis make immunoglobulin E antibodies to plaque constituents.
D000818:Animals; D000888:Antibodies, Anti-Idiotypic; D000917:Antibody Formation; D003773:Dental Plaque / Q000276:immunology*; D000882:Haplorhini; D006358:Hot Temperature; D006801:Humans; D007073:Immunoglobulin E; D010323:Passive Cutaneous Anaphylaxis; D010518:Periodontitis / Q000276:immunology*; D011935:Reagins / Q000096:biosynthesis*
D000888:Antibodies, Anti-Idiotypic; D011935:Reagins; D007073:Immunoglobulin E