title: Aspirin and ulcers.
abstract: In eastern Australia, there is an epidemic of gastric ulcer which began 30 years in young women who are now middle-aged, (b) This epidemic is associated with the regular use of aspirin most often in the form of A.P.C. powders taken for non-medical reasons, (c) Data from three separate studies in America confirms a statistically significant association of regular aspirin use and chronic gastric ulcer, and (d) An explanation is provided by the effect of aspirin in inhibiting prostaglandin synthetase.
mesh_terms: D001241:Aspirin / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use; D016861:Cyclooxygenase Inhibitors; D005260:Female; D006801:Humans; D008297:Male; D013276:Stomach Ulcer / Q000139:chemically induced*
chemical_list: D016861:Cyclooxygenase Inhibitors; D001241:Aspirin