[Changes of activity of alkaline phosphatase at the circulatory system in experimental hypertension of the rat (author's transl)].
Changes of activity of the alkaline phosphatase are investigated in the border of the outer media of vessels in two different models of hypertension (Goldblatt and Carotis-Sinus) in the rat. After onset of hypertension an increase of activity takes place in an area largely overlapping a necrosis of the outer medial region of the aorta. The formation of regenerated tissue leads to a thickening of the adventitia and to a decrease of the activities. Changes of the activities in the peripheral vessels presumably are due to participation of other factors. Indications to this effect are discussed.
D000469:Alkaline Phosphatase / Q000032:analysis*; D000818:Animals; D001808:Blood Vessels / Q000201:enzymology*; D006651:Histocytochemistry; D006973:Hypertension / Q000201:enzymology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D000469:Alkaline Phosphatase
Aktivitätsschwankungen der alkalischen Phosphatase am Gefässsystem bei der experimentellen Hypertonie der Ratte