title: Prostaglandin E1 (PGE1) in angiography of tumors of the extremities.
abstract: Prostaglandin E1 (PGE1) is a potent vasodilator. The value of this agent as an adjuvant in angiography of tumors of the extremities was evaluated in 10 patients. Except in one case involving a hemangioma, the diagnostic information concerning tumor vascularity and delineation of the extent of disease decreased after the use of PGE1. The visualization of small normal muscular arteries was improved. Therefore, the effect of PGE1 may be to preferentially increase the blood flow in normal tissues relative to the tumor. PGE1 seems to be of little value in enhancing the angiographic demonstration of neoplasms of the extremity.
mesh_terms: D000293:Adolescent; D000328:Adult; D000792:Angiography / Q000379:methods*; D001859:Bone Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging; D002648:Child; D005121:Extremities / Q000000981:diagnostic imaging*; D005260:Female; D005542:Forearm / Q000000981:diagnostic imaging; D005870:Giant Cell Tumors / Q000098:blood supply / Q000000981:diagnostic imaging; D006225:Hand / Q000000981:diagnostic imaging; D006391:Hemangioma / Q000098:blood supply / Q000000981:diagnostic imaging; D006392:Hemangioma, Cavernous / Q000098:blood supply / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000000981:diagnostic imaging; D009369:Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging*; D011458:Prostaglandins E; D013977:Tibia / Q000000981:diagnostic imaging; D014665:Vasodilator Agents
chemical_list: D011458:Prostaglandins E; D014665:Vasodilator Agents