title: Hyperbilirubinaemia and idiopathic hypopituitarism in the newborn period.
abstract: Two infants with idiopathic panhypopituitarism presented with severe neonatal hypoglycaemia, hepatomegaly and hyperbilirubinaemia (direct and indirect). Abnormal liver function tests returned to normal over a 5--8 month period. The growth rate in the absence of detectable growth hormone was 50% of normal during the first 6 months. The effect of growth hormone on somatomedin levels and growth rate during the first year of life in one of the infants is described.
mesh_terms: D000328:Adult; D005260:Female; D013006:Growth Hormone / Q000627:therapeutic use; D006529:Hepatomegaly / Q000209:etiology; D006801:Humans; D007003:Hypoglycemia / Q000151:congenital; D007018:Hypopituitarism / Q000151:congenital* / Q000175:diagnosis; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis; D007567:Jaundice, Neonatal / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D011247:Pregnancy; D013002:Somatomedins / Q000032:analysis
chemical_list: D013002:Somatomedins; D013006:Growth Hormone