Prevention of rhesus isoimmunization with intravenous anti-D gammaglobulin.
The prevention of rhesus isoimmunization was studied in 2247 rhesus negative mothers given varying intravenous doses of gammaglobulin (IgG) anti-D post partum. The results obtained show that 240 microgram of IgG anti-D affords excellent protection, if the efficacy of prophylaxis is monitored by a single fetal cell count at 72 hours after injection, and further doses of immunoglobulin are given in the few cases where fetal red cells remain in the circulation.
D000917:Antibody Formation; D004899:Erythroblastosis, Fetal / Q000517:prevention & control*; D004906:Erythrocyte Count; D005260:Female; D005312:Fetal Blood; D006801:Humans; D007074:Immunoglobulin G / Q000008:administration & dosage*; D007518:Isoantibodies; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System
D007074:Immunoglobulin G; D007518:Isoantibodies; D012204:Rh-Hr Blood-Group System