title: Plasmid-determined resistance to tellurium compounds.
abstract: Transferable plasmids in gram-negative bacteria that confer resistance to potassium tellurite or tellurate were found. This re-istance was distinct from resistance to mercury, silver, or arsenic compounds and was unrelated to antibiotic resistance. In Escherichia coli, plasmids determine a 100-fold increase in the minimal inhibitory concentration for tellurite and a 10-fold increase in tellurate resistance. Many, but not all, of the plasmids belong to incompatibility group S. In Pseudomonas aeruginosa, tellurium resistance is specifically associated with incompatibility group P-2 and involves a 5- to 10-fold increase in tellurite or tellurate resistance.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001149:Arsenates / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects*; D005111:Extrachromosomal Inheritance; D008628:Mercury / Q000494:pharmacology; D010957:Plasmids; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D012643:Selenium / Q000494:pharmacology; D012834:Silver / Q000494:pharmacology; D013691:Tellurium / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D001149:Arsenates; D012834:Silver; D008628:Mercury; D012643:Selenium; D013691:Tellurium