Lithium inhibits basal and food-stimulated gastrin secretion.
Ten psychiatric patients were given a protein-rich meal in periods on and off lithium administration. The concentrations of gastrin in serum were measured radioimmunochemically before and during the meal. The results show that lithium suppresses basal as well as food-stimulated gastrin secretion.
D000328:Adult; D005260:Female; D005502:Food; D005755:Gastrins / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006801:Humans; D008094:Lithium / Q000494:pharmacology* / Q000627:therapeutic use; D011618:Psychotic Disorders / Q000188:drug therapy
D005755:Gastrins; D008094:Lithium