title: Environmental factors affecting antipyrine metabolism in London factory and office workers.
abstract: 1 Measurements of antipyrine clearance in saliva have been made in 128 London factory and office workers. 2 Mean antipyrine clearance in 56 Asian immigrants was 40% slower than in 72 White subjects. 3 Although dietary differences existed between the two groups, analysis of their effect independently of race was impossible since all but one of the vegetarians were Asian and the non-vegetarians were nearly all White. 4 In the White subjects, use of the oral contraceptive reduced clearance by 38% in women, while cigarette smoking increase clearance by 38% in men.
mesh_terms: D000293:Adolescent; D000328:Adult; D000428:Alcohol Drinking; D000983:Antipyrine / Q000378:metabolism*; D001208:Asia / Q000208:ethnology; D004032:Diet; D004777:Environment; D005260:Female; D006207:Half-Life; D006801:Humans; D007700:Kinetics; D008131:London; D008297:Male; D008875:Middle Aged; D009787:Occupational Medicine; D044469:Racial Groups; D012737:Sex Factors; D012907:Smoking / Q000378:metabolism; D044465:White People
chemical_list: D000983:Antipyrine