title: Contrast medium reactions correlated with time of day.
abstract: Dynamic physiologic and psychological changes occur in patients awaiting excretory urography. A total of 2,000 patients were studied to see if rates of reaction to urographic contrast materials are influenced by the time of day such injections are given. Examinations performed between 7:00 A.M. and 2:00 P.M. were evaluated. The data suggest that reactions to radiographic contrast medium occur randomly and that a "safe" or "safer" time of day cannot be defined.
mesh_terms: D002940:Circadian Rhythm; D003973:Diatrizoate / Q000031:analogs & derivatives*; D003974:Diatrizoate Meglumine / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000503:physiopathology*; D006801:Humans; D014567:Urography / Q000009:adverse effects / Q000379:methods*
chemical_list: D003973:Diatrizoate; D003974:Diatrizoate Meglumine