Metabolism of vinyl chloride: destruction of the heme of highly purified liver Microsomal cytochrome P-450 by a metabolite.
D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006207:Half-Life; D006418:Heme / Q000378:metabolism*; D066298:In Vitro Techniques; D050356:Lipid Metabolism; D008315:Malondialdehyde / Q000378:metabolism; D008862:Microsomes, Liver / Q000187:drug effects* / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009251:NADPH-Ferrihemoprotein Reductase / Q000378:metabolism; D010545:Peroxides / Q000378:metabolism; D051381:Rats; D013438:Sulfhydryl Compounds / Q000378:metabolism; D014752:Vinyl Chloride / Q000378:metabolism*; D014753:Vinyl Compounds / Q000378:metabolism*
D010545:Peroxides; D013438:Sulfhydryl Compounds; D014753:Vinyl Compounds; D006418:Heme; D008315:Malondialdehyde; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D009251:NADPH-Ferrihemoprotein Reductase; D014752:Vinyl Chloride