High performance thin layer chromatography of neutral and acidic glycolipids: application to the chemical diagnosis of lipid storage diseases.
A new technique was utilized for the separation of neutral and acidic glycolipids using an equipment named U-Chamber System. This technique was employed for the chemical diagnosis of inherited inborn errors diseases in which complex glycolipids are involved. Results in the identification of storage products in Tay-Sachs' disease, GM1 gangliosidosis and Fabry's disease are presented.
D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods; D005733:Gangliosidoses / Q000175:diagnosis* / Q000652:urine; D006017:Glycolipids / Q000652:urine*; D006801:Humans
D006017:Glycolipids