[Vasodilator treatment of the acute phase of myocardial infarct with phentolamine. Analysis of hemodynamic results and therapeutic indications].
Treatment by phentolamine was carried out in 30 patients presenting with an acute myocardial infarction complicated by left ventricular failure, 8 of which had cardiogenic shock. The response to treatment was closely related to the level of overload of the left ventricle. Significant improvement in the haemodynamic state was only observed in the most severe cases of cardiac failure, and in these cases was accompanied by only a minimal and insignificant change in mean arterial pressure and heart rate.
D000208:Acute Disease; D001794:Blood Pressure / Q000187:drug effects; D003326:Coronary Circulation / Q000187:drug effects; D003331:Coronary Vessels / Q000187:drug effects*; D004341:Drug Evaluation; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy*; D010646:Phentolamine / Q000627:therapeutic use*; D012770:Shock, Cardiogenic / Q000188:drug therapy; D014665:Vasodilator Agents
D014665:Vasodilator Agents; D010646:Phentolamine
Le traitement vasodilatateur par la phentolamine à la phase aiguë de l'infarctus du myocarde. Analyse des résultats hémodynamiques et indications thérapeutiques.