Mechanical responses of the isolated cervix of the day-22 pregnant rat to field stimulation.
Field stimulation of isolated, spirally-cut cervix from day-22 pregnant rats produced contractions which could be inhibited by tetrodotoxin or hyoscine and potentiated by propranolol. The rat cervix would appear to receive both cholinergic and noradrenergic innervations whose transmitters activate muscarinic cholinoceptors and beta-adrenoceptors respectively.
D000320:Adrenergic Fibers / Q000502:physiology; D000818:Animals; D002584:Cervix Uteri / Q000294:innervation* / Q000502:physiology; D002799:Cholinergic Fibers / Q000502:physiology; D004558:Electric Stimulation; D005260:Female; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects; D010646:Phentolamine / Q000494:pharmacology; D011247:Pregnancy; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D012601:Scopolamine / Q000494:pharmacology; D013779:Tetrodotoxin / Q000494:pharmacology
D013779:Tetrodotoxin; D011433:Propranolol; D012601:Scopolamine; D010646:Phentolamine