title: The effect of prostaglandins on the isolated internal muscles of the mammalian eye, including man.
abstract: The effects of PG's on the isolated intraocular muscles were determined in cat, rabbit, monkey and man, as well as their interactions with cholinergic agents and with catecholamines; the effects of PG antagonists; the effects of PG synthetase inhibitors; and the effects of cholinergic and adrenergic blockade and depletion. It is speculated that PG's may be involved in the regulation of the pupil and accommodation.
mesh_terms: D000818:Animals; D002395:Catecholamines / Q000494:pharmacology; D002415:Cats; D004357:Drug Synergism; D005123:Eye / Q000187:drug effects*; D000882:Haplorhini; D006801:Humans; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects*; D010276:Parasympatholytics / Q000494:pharmacology; D011448:Prostaglandin Antagonists; D011453:Prostaglandins / Q000096:biosynthesis / Q000494:pharmacology*; D011817:Rabbits; D013565:Sympatholytics / Q000494:pharmacology
chemical_list: D002395:Catecholamines; D010276:Parasympatholytics; D011448:Prostaglandin Antagonists; D011453:Prostaglandins; D013565:Sympatholytics