title: [Change in the exocrine function of the liver after cholecystectomy under the influence of diet therapy].
abstract: In patients with sustained cholecystectomy the content of the basic bile components (cholesterol, cholic acid, total phosphorus) was measured. The cholate-cholesterol coefficient, enabling it to a certain degree to evaluate the lithogeneity of the bile, was calculated. The cholesterol concentration in the serum and bile was contrasted. A total of 104 patients were examined at different post-operative periodss and it was found that in 70 per cent of them the bile was not oversaturated with cholesterol. Two variants of the No. 5 diet were used--the sparing and fatty, differing in the amount of fat and carbohydrates. Under the effect of the No. 5 sparing diet a reduced serum cholesterol concentration was noted along with a noticeable rise of the cholic acid content in the bile with a not too brusque rise of the cholesterol level therein, which led to an increase of the cholate-cholesterol coefficient. Against the background of the treatment with a No. 5 fat diet in evidence was a diminution of the serum cholesterol content, a clearcut fall in the cholesteroland cholic acid concentration in the bile with a continuing fairly high cholate-chole sterol coefficient.
mesh_terms: D000328:Adult; D001646:Bile / Q000378:metabolism; D002763:Cholecystectomy; D002769:Cholelithiasis / Q000178:diet therapy* / Q000503:physiopathology; D002779:Cholestasis / Q000178:diet therapy; D002784:Cholesterol / Q000097:blood; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004041:Dietary Fats / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008099:Liver / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged
chemical_list: D004040:Dietary Carbohydrates; D004041:Dietary Fats; D002784:Cholesterol
vernacular_title: Izmenenie vneshnesekretornoĭ funktsii pecheni u bol'nykh posle kholetsistéktomii pod vliianiem dietoterapii.