[Hypernatremia and adipsia (author's transl)].
We have studied an infant (female) with a persisting hypernatremia and adipsia, examined for the first time at the age of five months. The funtional test carried out showed an insensibility of the osmoreceptors for very important changes in POsm. carryng with them a lack of response of the ADH. Neuroradiological studies demostrated hydrocephalia secondary to a stenosis of the aqueduct of Silvio. Treatment with chlorpropamide proved effective. The literature is being revised comparing out results with those of other authors.
D002747:Chlorpropamide / Q000627:therapeutic use*; D003681:Dehydration / Q000150:complications* / Q000628:therapy; D004231:Diuresis; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging; D006955:Hypernatremia / Q000150:complications* / Q000188:drug therapy / Q000628:therapy; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology; D007223:Infant; D009994:Osmolar Concentration; D011859:Radiography; D012462:Saline Solution, Hypertonic; D014667:Vasopressins / Q000494:pharmacology*; D014882:Water-Electrolyte Balance
D012462:Saline Solution, Hypertonic; D014667:Vasopressins; D002747:Chlorpropamide
Hipernatremia y adipsia en un lactante hidrocefálico.