[Extraction of cholesterol from vessel walls by surface-active agents and organic solvents].
Low concentrations (0.1--1.0%) of surface-active substances Tween-20, Triton X-100 and sodium deoxycholate were shown to extract 20--40% of cholesterol from dog vessel wall. Dioxane was effective at high concentrations (80--100%). As contrast to dioxane, ethanol extracted up to 20% of cholesterol at low concentrations (10--20%). The thickened intima of the atherosclerotic vessel is the significant barrier for the extraction of cholesterol.
D000818:Animals; D001011:Aorta / Q000032:analysis; D001808:Blood Vessels / Q000032:analysis*; D002784:Cholesterol / Q000302:isolation & purification*; D004146:Dioxanes; D004285:Dogs; D000431:Ethanol; D012997:Solvents; D013501:Surface-Active Agents
D004146:Dioxanes; D012997:Solvents; D013501:Surface-Active Agents; D000431:Ethanol; D002784:Cholesterol
Ekstraktsiia kholesterina iz stenki sosuda poverkhnostno-aktivnymi veshchestvami i organicheskimi rastvoriteliami.