[Effects of hyperpolarizing currents on the action potentials of nodal and perinodal sino-atrial cells of the rabbit heart].
A technique of focal polarization allowed us to confirm that the action potentials of the true rabbit heart pacemaker cells possess a rapid sodium channel normally inactivated because of the low value of the take-off potential of this tissue. The latent pacemaker cells are regular sinocaval cells depolarized as a consequence of the proximity of true pacemaker cells.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D004558:Electric Stimulation; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects; D011817:Rabbits; D012849:Sinoatrial Node / Q000502:physiology*; D013779:Tetrodotoxin / Q000494:pharmacology; D014683:Vena Cava, Superior / Q000294:innervation / Q000502:physiology
D013779:Tetrodotoxin
Effets des courants hyperpolarisants sur les potentiels d'action des cellules sino-atriales nodales et périnodales du coeur de lapin.