[Tryptic enzymes in the differential diagnosis of inflammatory diseases of the colon (author's transl)].
Inflammatory diseases of the colon can be differentiated by means of their chymotrypsin A excretion in the stool. In proctosigmoiditis and a group of comparable gastroenterological cases, the mean excretion level is between 170 and 200 mug per gram of stool. The chymotrypsin A level in proctocolitis, on the other hand, is significantly higher in all stages and increases with increasing activity of the disease. This brings a further diagnostic criterion to the clinical and endoscopic differences between proctosigmoiditis and proctocolitis (colitis ulcerosa). The fundamentally different behavior in the excretion of chymotrypsin A in the stool supports the hypothesis of two diseases differing from each other.
D002918:Chymotrypsin / Q000032:analysis*; D003092:Colitis / Q000201:enzymology*; D003093:Colitis, Ulcerative / Q000201:enzymology; D012809:Colon, Sigmoid; D003937:Diagnosis, Differential; D005243:Feces / Q000201:enzymology; D006801:Humans; D011349:Proctitis / Q000201:enzymology
D002918:Chymotrypsin
Tryptische Fermente in der Differentialdiagnose entzündlicher Kolonerkrankungen