title: Tween 80/diatrizoate enemas in bowel obstruction.
abstract: Although successful treatment of meconium ileus with Gastrografin enema has been attributed to the hypertonicity of this material, Tween 80, present in a 0.75% concentration, may be its most effective component. Tween 80 acts as a surface-active substance and stool emulsifier. An enema solution of 1%-2% Tween 80 and isotonic sodium diatrizoate has been effective in the relief of meconium or fecal mass obstruction in infants and children.
mesh_terms: D000293:Adolescent; D002675:Child, Preschool; D003973:Diatrizoate / Q000627:therapeutic use*; D004733:Enema; D005244:Fecal Impaction / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000628:therapy; D007415:Intestinal Obstruction / Q000628:therapy*; D008297:Male; D008470:Meconium; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D011136:Polysorbates / Q000627:therapeutic use*
chemical_list: D011136:Polysorbates; D003973:Diatrizoate; D011092:Polyethylene Glycols