Vascular malformations of the spinal cord (angiodysgenetic myelomalacia): a critique on its pathogenesis.
Two cases of angiodysgenetic myelomalacia are presented. Both patients had progressive weakness and sensory deficits in the lower extremities and vascular malformations of their spinal cords. The lesions were located on the dorsum of the spinal cord and the dorso-spinal roots. We believe the symptoms that developed later in life were due to spinal cord ischemia resulting from late degenerative changes in the vessels of the malformation and an ever increasing spinal "steal".
D000368:Aged; D001344:Autopsy; D001808:Blood Vessels / Q000002:abnormalities; D000013:Congenital Abnormalities / Q000150:complications; D006801:Humans; D007511:Ischemia / Q000209:etiology / Q000473:pathology; D008297:Male; D009187:Myelitis / Q000209:etiology / Q000473:pathology*; D013116:Spinal Cord / Q000098:blood supply