title: Ambruticin (W7783), a new antifungal antibiotic.
abstract: Ambruticin represents a new class of antibiotics isolated from a strain of Polyangium cellulosum var, fulvum, a bacterium belonging to the class Myxobacteriales. This antibiotic is a cyclopropyl-polyene-pyran acid and is active in vitro against fungi.
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000032:analysis / Q000096:biosynthesis* / Q000494:pharmacology; D005285:Fermentation; D007928:Lethal Dose 50; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051379:Mice; D008826:Microbial Sensitivity Tests; D009231:Myxococcales / Q000378:metabolism; D011714:Pyrans / Q000096:biosynthesis / Q000494:pharmacology; D013055:Spectrophotometry, Infrared
chemical_list: D000935:Antifungal Agents; D011714:Pyrans