title: An effective, simplified medium for the culture of Neisseria gonorrhoeae.
abstract: A new culture medium for Neisseria gonoorhoeae is described. The frequency of isolation of gonococci was significantly higher when this medium was used than when Thayer-Martin medium containing vancomycin, colistin, and nystatin was used in a study of cervical, urethral, and analy specimens. In a similar comparative study, Thayer-Martin medium containing trimethoprim and polymyxin B as antimicrobial agents gave a significantly lower frequency of isolation of gonococci than did the new medium. A modified McLeod medium containing human placenta was found to have the same high performance as the new medium, but, like the modified Thayer-Martin medium, the modified McLeod medium is more expensive and more difficult to prepare.
mesh_terms: D001003:Anal Canal / Q000382:microbiology; D002584:Cervix Uteri / Q000382:microbiology; D003470:Culture Media; D005260:Female; D006069:Gonorrhea / Q000382:microbiology; D006801:Humans; D008297:Male; D009344:Neisseria gonorrhoeae / Q000254:growth & development*; D014521:Urethra / Q000382:microbiology
chemical_list: D003470:Culture Media