title: Total body irradiation with 8 MeV X-rays in generalized malignant disease.
abstract: The authors describe their experience with total body irradiation (TBI) with 8 MeV-x rays in the treatment of disseminated tumors. With a dose of 125 rad, given three times with 2-week intervals, some objective remissions (6/26) were obtained, especially in patients with lymphomas. For solid tumors only subjective improvement could be achieved. The side-effects were acceptable. The authors came to the conclusion that total body irradiation may be an alternative to chemotherapy for certain cases of generalized cancer.
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002908:Chronic Disease; D005260:Female; D006689:Hodgkin Disease / Q000532:radiotherapy; D006801:Humans; D007938:Leukemia / Q000532:radiotherapy; D008223:Lymphoma / Q000532:radiotherapy; D008297:Male; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D011882:Radiotherapy, High-Energy / Q000009:adverse effects / Q000379:methods
chemical_list: D000970:Antineoplastic Agents