title: Behçet's syndrome. Report of a case associated with pericardial effusion and cryoglobulinemia treated with indomethacin.
abstract: A patient with Behçet's syndrome manifested by optic atrophy, purulent conjunctivitis and orogenital ulcerations presented with a high fever and pericardial effusion. A mixed cryoglobulinemia (immunoglobulin A (IgA)-immunoglobulin G (IgG)) was observed. Treatment with indomethacin resulted in rapid defervescence, resolution of the pericardial effusion and the orogenital ulcerations, and disappearance of the cryoglobulinemia. Discontinuation of indomethacin therapy was followed by a recurrence of the oral and genital ulcerations that responded promptly to the reinstitution of indomethacin treatment.
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D003450:Cryoglobulins; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007213:Indomethacin / Q000627:therapeutic use*; D008297:Male; D010265:Paraproteinemias / Q000150:complications*; D010490:Pericardial Effusion / Q000150:complications*
chemical_list: D003450:Cryoglobulins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007213:Indomethacin