title: Tissue response to silicone rubber when used as a root canal filling.
abstract: To test the tissue compatibility of silicone rubber when it is used as a root canal filler, excess material was intentionally forced into the apical tissues in primates. The tissue response was one of general acceptance, with the usual response being fibrotic encapsulation. A low degree of inflammation was noted. Further studies are in progress.
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000033:anatomy & histology; D000882:Haplorhini; D006801:Humans; D007568:Jaw / Q000033:anatomy & histology; D008253:Macaca mulatta; D010486:Periapical Tissue / Q000033:anatomy & histology / Q000187:drug effects*; D010513:Periodontal Ligament / Q000033:anatomy & histology; D010518:Periodontitis / Q000209:etiology; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D012389:Root Canal Obturation; D012826:Silicone Elastomers / Q000494:pharmacology*
chemical_list: D012387:Root Canal Filling Materials; D012826:Silicone Elastomers