Defects of the central nervous system in Finland. IV. Associations with diagnostic x-ray examinations.
Based on the Finnish Register of Congenital Malformations a search was undertaken to find possible associations between defects of the CNS and diagnostic x-ray examinations of the mother during pregnancy as well as pelvic x-ray examinations prior to pregnancy. Time-area--matched pregnancies and polydactylic children were used as controls. The risk of having a microcephalic child was increased for mothers with pelvic x-ray prior to pregnancy, but the number of discordant pairs was small. Of the examinations performed during pregnancy, fetal x-ray was significantly more common among mothers who delivered a CNS-defective child. No associations were observed for other kinds of examinations.
D000016:Abnormalities, Radiation-Induced / Q000453:epidemiology*; D005260:Female; D005333:Fetus / Q000528:radiation effects*; D006801:Humans; D007231:Infant, Newborn; D008400:Mass Chest X-Ray / Q000009:adverse effects; D009436:Neural Tube Defects / Q000453:epidemiology* / Q000209:etiology; D010387:Pelvimetry / Q000009:adverse effects*; D011247:Pregnancy; D011859:Radiography / Q000009:adverse effects*