Application of freeze-dried monkey erythrocytes to measles viral hemagglutination and hemagglutination-inhibition tests.
Erthrocytes collected from monkey species including grivet, rhesus, and cynomolgus monkeys were stabilized by fixation with glutaraldehyde of a low concentration and were freeze-dried in vacuo. These freeze-dried erythrocytes were compared with fresh erythrocytes for measles viral hemagglutination and hemagglutination inhibition and could be used in both tests instead of fresh erythrocytes. They maintained their initial appearance and sensitivity to measles viral hemagglutinins after storage at 4 degrees C for 4 months more.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D004912:Erythrocytes; D005612:Freeze Drying; D000882:Haplorhini; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D008252:Macaca fascicularis; D008253:Macaca mulatta; D008459:Measles virus / Q000276:immunology*
D000914:Antibodies, Viral