Genetics of cycloheximide resistance in Tetrahymena.
Cycloheximide resistance in Tetrahymena is inducible by mutagenesis. Two mutations, isolated independently from genetically different strains, were analyzed. The two mutations, Chx-1 and Chx-2, were found to be alleles at the same locus. A specific analysis is presented which may serve as a model for strategies employing an independent manipulation of the micro-and macronuclei of this organism for genetic studies.
D000483:Alleles; D002467:Cell Nucleus; D002874:Chromosome Mapping; D003513:Cycloheximide / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D005799:Genes, Dominant; D005816:Genetic Complementation Test; D010641:Phenotype; D013769:Tetrahymena pyriformis / Q000187:drug effects / Q000235:genetics*
D003513:Cycloheximide