title: [The effects of diverse agents (Ca++ and K++  ionophores, organomercurials, dithiols, colchicine, and cytochalasin B) on the maturation and differentiation without cleavage in Chaetopterus eggs].
abstract: Induction of maturation in Chaetopterus oocytes requires the presence of Ca++ ions in the medium, but differentiation without cleavage can proceed in the absence of this cation. The Ca++ ionophore A 23187 induces both maturation and the cortical reaction provided that Ca++ ions are present in the medium differentiation without cleavage may follow. Valinomycin slowly induces germinal vesicle breakdown, which is followed by a sharp segregation between hyaloplasm and yolk. PHMPS, but not DTT, induces maturation. Differentiation without cleavage is more sensitive to colchicin than to cytochalasin B.
mesh_terms: D000818:Animals; D000001:Calcimycin / Q000494:pharmacology; D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D003078:Colchicine / Q000494:pharmacology; D003571:Cytochalasin B / Q000494:pharmacology; D004261:DNA Replication; D004229:Dithiothreitol / Q000494:pharmacology; D005260:Female; D010063:Ovum / Q000166:cytology / Q000187:drug effects*; D010663:Phenylmercury Compounds / Q000494:pharmacology; D011077:Polychaeta; D014634:Valinomycin / Q000494:pharmacology
chemical_list: D010663:Phenylmercury Compounds; D014634:Valinomycin; D000001:Calcimycin; D003571:Cytochalasin B; D003078:Colchicine; D004229:Dithiothreitol
vernacular_title: Effets de divers agents (ionophores du Ca++ et du K+, organomercuriels, dithiols, colchicine et cytochalasine B) sur la différenciation sans clivage chez l'oeuf de chétoptère.