title: [Lumbar myelography with methylglucamine-iocarmate (dimer-x). A critical review of neurological complications (author's transl)].
abstract: A critical literature review is presented on the basis of our own clinical experiences with complications and distressing side effects of the lumbar Dimer-X myelography. Severe Complications such as spinal and conuscauda-symptoms, epileptic seizures, amnestic episodes and late palsies of the Abducens nerve in literature range between 1 and 9%. Unspecific side effects which cannot clearly be differentiated from pure post-lumbal puncture complaints are reported to occur in up to 28%. The probably underlying pathogenetic mechanisms are discussed together with former animal experiments which revealed a local toxity of the contrast medium at the central nervous tissue and the surrounding membranes.
mesh_terms: D000010:Abducens Nerve; D000707:Anaphylaxis / Q000139:chemically induced; D004827:Epilepsy / Q000139:chemically induced; D006801:Humans; D007482:Iothalamate Meglumine / Q000009:adverse effects*; D008161:Lumbosacral Region; D009192:Myelography / Q000009:adverse effects*; D010243:Paralysis / Q000139:chemically induced; D013118:Spinal Cord Diseases / Q000139:chemically induced*
chemical_list: D007482:Iothalamate Meglumine
vernacular_title: Die lumbale Myelographie mit Methylglucamin-Jocarmat (Dimer-X). Eine kritische Ubersicht neurologischer Komplikationen.