[Preventive effects of gliclazide on the development of cholesterol induced atherosclerosis in rabbits].
Administration of gliclazide inhibited the development of aortic and particularly coronary lesions induced by the cholesterol-containing diet; but it did not noticeably affect the evolution of plasma lipid disturbances.
D000818:Animals; D001012:Aorta, Abdominal / Q000473:pathology; D001013:Aorta, Thoracic / Q000473:pathology; D001161:Arteriosclerosis / Q000139:chemically induced / Q000503:physiopathology / Q000517:prevention & control*; D002788:Cholesterol Esters / Q000097:blood; D002791:Cholesterol, Dietary; D005907:Gliclazide / Q000627:therapeutic use*; D009206:Myocardium / Q000473:pathology; D010743:Phospholipids / Q000097:blood; D051381:Rats; D013453:Sulfonylurea Compounds / Q000627:therapeutic use*; D014280:Triglycerides / Q000097:blood
D002788:Cholesterol Esters; D002791:Cholesterol, Dietary; D010743:Phospholipids; D013453:Sulfonylurea Compounds; D014280:Triglycerides; D005907:Gliclazide
Effets préventifs du gliclazide sur le développement de l'athérosclérose induite par le cholestérol chez la lapin.