The social outcome of patients in a trial of long-term continuation therapy in schizophrenia: pimozide vs. fluphenazine.
A blind social assessment at home carried out twice during a year's follow-up of 41 patients on continuation therapy, 21 randomly allocated to pimozide tablets and 20 to fluphenazine decanoate injections. Patients on pimozide were significantly more favourably rated on aspects of sociability, use of leisure, warmth of personal relationships, household tasks and child-rearing. The mode of production of this result is discussed.
D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004651:Employment; D004739:England; D005260:Female; D005476:Fluphenazine / Q000627:therapeutic use*; D006801:Humans; D007398:Interpersonal Relations; D007899:Leisure Activities; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D010868:Pimozide / Q000627:therapeutic use*; D012008:Recurrence; D012559:Schizophrenia / Q000188:drug therapy*; D012917:Social Adjustment
D010868:Pimozide; D005476:Fluphenazine