Gastric patch esophagoplasty: an experimental study.
To determine whether the use of pedicled full-thickness gastric patches would be feasible and safe in esophageal reconstruction, studies were undertaken in eleven dogs. The results demonstrate that patches containing parietal cell mucosa are likely to produce localized adjacent esophagitis. Patches containing antral mucosa do not produce esophagitis and are not associated with a subsequent increase in circulating serum gastrin levels.
D000818:Animals; D004285:Dogs; D004941:Esophagitis / Q000209:etiology; D004944:Esophagoplasty / Q000379:methods*; D005753:Gastric Mucosa / Q000378:metabolism*; D005755:Gastrins / Q000097:blood; D013270:Stomach / Q000637:transplantation*; D014182:Transplantation, Autologous / Q000009:adverse effects
D005755:Gastrins