Lingual carcinogenesis in an inbred strain of hamsters.
Epidermoid carcinoma of the lateral border of the tongue can be induced in a standard strain of hamsters, applying DMBA in acetone after traumatizing the area with a root canal broach. Employing the same technique in an inbred strain of hamsters resulted in the more rapid development of carcinomas. The inbred strain should be a useful model for experimental carcinogenesis of tongue.
D015127:9,10-Dimethyl-1,2-benzanthracene; D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced* / Q000473:pathology; D006224:Cricetinae; D009374:Neoplasms, Experimental / Q000473:pathology; D014062:Tongue Neoplasms / Q000139:chemically induced* / Q000473:pathology
D015127:9,10-Dimethyl-1,2-benzanthracene