title: Epidermal cells adhere preferentially to type IV (basement membrane) collagen.
abstract: Epidermal cells from adult guinea pig skin attach and differentiate preferentially on substrates of type IV (basement membrane) collagen, compared to those of types I--III collagen. In contrast, guinea pig dermal fibroblasts attach equally well to all four collagen substrates. Fibronectin mediates the attachment of fibroblasts but not of epidermal cells to collagen.
mesh_terms: D001769:Blood; D002448:Cell Adhesion / Q000187:drug effects; D002455:Cell Division; D003094:Collagen; D000078404:Epidermal Cells; D005347:Fibroblasts / Q000166:cytology; D006023:Glycoproteins / Q000494:pharmacology; D007700:Kinetics
chemical_list: D006023:Glycoproteins; D003094:Collagen