[Modification of chromatin condensation in cultured macrophages during induction of cell division by an inflammatory exudate].
The determination of chromatin condensation in rat peritoneal macrophages in culture showed a predominance of heterochromatin with low transcriptory activity. After induction of division in rat peritoneal macrophages in culture by an acute inflammatory exudate, a decrease of heterochromatin and an increase of euchromatin were observed. This result brings further evidence to support previous observations according to which this type of exudate shows mitogenic properties.
D000818:Animals; D002455:Cell Division; D002478:Cells, Cultured; D002843:Chromatin / Q000502:physiology*; D003470:Culture Media; D003911:Dextrans; D005122:Exudates and Transudates; D006570:Heterochromatin / Q000502:physiology; D007249:Inflammation / Q000139:chemically induced / Q000503:physiopathology*; D008264:Macrophages / Q000502:physiology*; D008297:Male; D051381:Rats
D002843:Chromatin; D003470:Culture Media; D003911:Dextrans; D006570:Heterochromatin
Modifications de la condensation chromatinienne de macrophages en culture au cours de l'induction de leur division par un exsudat inflammatoire.