[Electron absorption and fluorescence spectra of carbonyl--conjugated pentaenes in various media].
It was found that fluorescence intensity of carbonyl-conjugated pentaens of flavofungin flavopentin and brunefungin in solutions depended on the solvent polarity and specific interactions of the antibiotics with the solvents. Addition of cholesterol into the aqueous solutions of these antibiotics resulted in a hypsochrome shift in their absorption spectra and increased fluorescence intensity. The antibiotics were found by their fluorescence in the yeast cells sensitive to them when their content was close to the concentrations resulting in the cell lysis. Low concentrations of the antibiotics resulted in changed localization of the yeast self fluorescence.
D000935:Antifungal Agents / Q000032:analysis*; D002784:Cholesterol; D008826:Microbial Sensitivity Tests; D008856:Microscopy, Fluorescence; D012996:Solutions; D013050:Spectrometry, Fluorescence; D013054:Spectrophotometry, Atomic; D013535:Suspensions; D015003:Yeasts / Q000187:drug effects
D000935:Antifungal Agents; D012996:Solutions; D013535:Suspensions; D002784:Cholesterol
Elektronnye spektry pogloshcheniia i fliuorestsentsii karbonil--kon"iugirovannykh pantaenov v razlichnykh sredakh.