Enhancement of acetylcholine secretion by two sulfhydryl reagents.
Two sulfhydryl reagents (N-ethyl maleimide and p-chloromercuribenzoate), used in a concentration of 0.1 mmol/l, increased both spontaneous and evoked acetylcholine secretion at the toad neuromuscular junction, the former in the absence of extracellular calcium ions.
D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D002024:Bufo marinus; D002729:Chloromercuribenzoates / Q000494:pharmacology*; D004558:Electric Stimulation; D005033:Ethylmaleimide / Q000494:pharmacology*; D005071:Evoked Potentials / Q000187:drug effects; D066298:In Vitro Techniques; D009045:Motor Endplate / Q000378:metabolism; D013268:Stimulation, Chemical
D002729:Chloromercuribenzoates; D000109:Acetylcholine; D005033:Ethylmaleimide