Heart preservation by means of a complex artificial perfusion fluid.
Heart storage for different time intervals of up to 72 hours was carried out using a complex perfusion fluid elaborated according to a personal new theoretical concept. The recovery of the hearts stored by means of this fluid was practically integral as shown by the measurements and recordings of several cardiac functional parameters within a period of 5-7 hours of ex vivo functional testing subsequent to the storage. This fluid was also found to allow repeated heart storages for 24 hours alternating with efficient ex vivo functional testing for periods of 5-7 hours. Such performances in heart preservation were not yet reported elsewhere. This fluid was thought to allow an efficient ex vivo heart conditioning before transplantation by immunological or pharmacological treatments throughout repeated short-term or long-term alternating storages and recoveries.
D000596:Amino Acids; D000818:Animals; D004285:Dogs; D016027:Heart Transplantation; D010477:Perfusion / Q000379:methods; D012996:Solutions; D013997:Time Factors; D014021:Tissue Preservation / Q000379:methods*; D014184:Transplantation, Homologous
D000596:Amino Acids; D012996:Solutions