[Comparison of the sebaceous secretions of the skin of the forehead under the treatment with three oral contraceptives. Diane, Neogynon and Lyndiol (author's transl)].
Ten women who took oral contraceptives for six months or longer were investigated. The women took in a randomized sequence cyproteronazetate 2 mg. ethinyloestradiol 50 mcg. (Diane), D-Norgestrel 0.25 mg., ethinyloestradiol 50 mcg. (Neogynon), and Lynestrenol 2.5 mg. with ethinyloestradiol 50 mcg. (Lyndiol). During each treatment cycle at four defined pounts the sebaceous secretions from the skin of the forehead was measured. Since each patient received one cycle of each of the oral contraceptives each patient served as her own control. With Diane and Neogynon the sebaceous secretions were the same. With ingestion of Lyndiol there was a significantly higher sebaceous secretion than with the other two oral contraceptives (p less than 0.05, t-test for paired observations).
D000328:Adult; D003276:Contraceptives, Oral; D003278:Contraceptives, Oral, Hormonal; D003534:Cyproterone / Q000494:pharmacology*; D004997:Ethinyl Estradiol / Q000494:pharmacology*; D005260:Female; D005546:Forehead; D006801:Humans; D008234:Lynestrenol / Q000494:pharmacology*; D008598:Menstruation; D009644:Norgestrel / Q000494:pharmacology*; D012627:Sebaceous Glands / Q000187:drug effects*; D013997:Time Factors
D003276:Contraceptives, Oral; D003278:Contraceptives, Oral, Hormonal; D009644:Norgestrel; D004997:Ethinyl Estradiol; D003534:Cyproterone; D008234:Lynestrenol
Vergleich der Talgsekretion der Stirnhaut bei Behandlung mit drei kontrazeptiven Pillen: Cyproteronazetat 2 mg mit Athinylöstradiol 50 microgram (Diane), D-Norgestrel 0,25 mg mit Athinylöstradiol 50 microgram (Neogynon) und Lynestrenol 2,5 mg mit Athinylöstradiol 50 microgram (Lyndiol).