title: [Management of gastrointestinal diseases using a motility-regulating preparation. Results of a field study using bromopride (Viaben) conducted by 530 general practitioners on 4182 patients].
abstract: Abnormalities of oesophago-gastro-intestinal motoricity play an important etiologic role in various affections of stomach, intestine, oesophagus and associated complaints. The new monosubstance bromopride produces a selective action restoring the basal motility of stomach, pylorus, duodenum and of the lower oesophageal sphincter to normal. The effect and tolerance of Viaben (bromopride) were examined in an open field study on 4182 subjects. The drug was given in average doses of one capsule three times a day. The results were assessed as very good in 37.9% of cases, and as good in 47.9%. No change was seen in 12.2%, while only 2.0% were aggravated. 64.7% of all patients benefited within the first fortnight. Nausea, vomiting and intolerance to drugs even disappeared in the first days of treatment. Individuals exhibiting a nervous, irritative stomach also had a rapid response to the drug. Pain, which is a fairly common complaint, passed off quickly. Side effects were seen in 6.8% of cases. However, the question whether they were due to the treatment, is not easily answered in an open study. The most common side effect was tiredness (3.7%), which was reported to be mild in some cases. The dyskinesia observed in subjects treated with other ortho-substituted benzamides was only seen in 0.4% of all patients.
mesh_terms: D001549:Benzamides / Q000494:pharmacology / Q000627:therapeutic use*; D001657:Biliary Dyskinesia / Q000188:drug therapy; D004378:Duodenal Diseases / Q000188:drug therapy; D005756:Gastritis / Q000188:drug therapy; D005759:Gastroenteritis / Q000188:drug therapy; D005767:Gastrointestinal Diseases / Q000188:drug therapy*; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans
chemical_list: D001549:Benzamides
vernacular_title: Behandlung gastrointestinaler Erkrankungen mit einem motilitätsregulierenden Präparat. Ergebnisse einer Feldstudie mit Bromoprid (Viaben) bei 4182 Patienten durch 530 niedergelassene Arzte.