title: Circadian rhythm of serotonin N-acetyltransferase activity in organ culture of chicken pineal gland.
abstract: When chicken pineal glands were organ-cultured in darkness, serotonin N-acetyltransferase activity was low during daytime, increased at midnight, and decreased on the next morning. The autonomous increase of N-acetyltransferase activity was suppressed by illumination of the glands. When pineal glands were cultured under a light-dark cycle (LD 12:12), the change of N-acetyltransferase activity continued to oscillate in phase with the light-dark cycle for 3 days.
mesh_terms: D000123:Acetyltransferases / Q000378:metabolism*; D000818:Animals; D002645:Chickens; D002940:Circadian Rhythm; D003624:Darkness; D008027:Light; D008550:Melatonin / Q000096:biosynthesis; D009924:Organ Culture Techniques; D010870:Pineal Gland / Q000201:enzymology / Q000502:physiology*; D012701:Serotonin
chemical_list: D012701:Serotonin; D000123:Acetyltransferases; D008550:Melatonin