title: Observations on the association of annulate lamellae with vinblastine-induced paracrystals in tumour cells in vitro.
abstract: Tumour cells in vitro responded to prolonged treatment with colchicine with the formation of annulate lamellae. Following the colchicine treatment, paracrystals were induced with vinblastine. A close association of annulate lamellae with vinblastine-induced crystals was observed. The hypothesis that annulate lamellae and the related unclear membrane with the pore complexes may play a role in the control of the cytoplasmic microtubule complex is discussed.
mesh_terms: D000818:Animals; D002460:Cell Line; D003078:Colchicine / Q000494:pharmacology; D051379:Mice; D008854:Microscopy, Electron; D008870:Microtubules; D009374:Neoplasms, Experimental / Q000473:pathology*; D009685:Nuclear Envelope; D014747:Vinblastine / Q000494:pharmacology*
chemical_list: D014747:Vinblastine; D003078:Colchicine