title: Detection, localization, and treatment of occult bronchogenic carcinoma in nickel workers.
abstract: Asymptomatic men exposed to nickel sulfide prior to 1963 were studied prospectively to investigate cytologic abnormalities in the sputum. We discovered a considerably greater incidence of squamous cell tumors that would have been expected from subjects exposed only to cigarette smoke.
mesh_terms: D002283:Carcinoma, Bronchogenic / Q000139:chemically induced* / Q000175:diagnosis; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced; D006801:Humans; D008175:Lung Neoplasms / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects*; D009784:Occupational Diseases / Q000139:chemically induced*; D010087:Oxides; D011446:Prospective Studies; D012142:Respiratory Tract Neoplasms / Q000139:chemically induced; D012907:Smoking / Q000150:complications; D013183:Sputum / Q000166:cytology; D013440:Sulfides
chemical_list: D010087:Oxides; D013440:Sulfides; D009532:Nickel