title: [Pathophysiological prerequisites in the diagnosis and treatment of arterial occlusive diseases (author's transl)].
abstract: The pathophysiological consequences of an arterial occlusive disease are mainly governed by a) the location, degree, and temporal course of the vascular obstruction, b) the installation of a sufficient arterio-arterial bypass of the site of obstruction, and c) the behaviour of the postocclusive arterial vascular region. The acute total blockage of a larger artery usually can be diagnosed without major difficulties (the problems of comparative indirect blood pressure measurements for the localization of the occlusion are discussed). A partial obstruction, on the contrast, may be secret in the beginning. A stenosis of longer duration can be followed by the poststenotic bulging of the vessel wall; in this area platelet microemboli can take their origin. Compared with a limitation of O2-supply by the occlusion of a larger vessel the direct obstruction of the microvasculature will result in a more severe disturbance of organ function.
mesh_terms: D000818:Animals; D001012:Aorta, Abdominal / Q000503:physiopathology; D001157:Arterial Occlusive Diseases / Q000503:physiopathology*; D001794:Blood Pressure; D004285:Dogs; D004548:Elasticity; D005263:Femoral Artery / Q000503:physiopathology; D010101:Oxygen Consumption; D011674:Pulse; D014655:Vascular Resistance
vernacular_title: Pathophysiologische Voraussetzungen für die Diagnostik und Therapie arterieller Verschlusskrankheiten.