Correlation of tartrazine hypersensitivity with specific serum IgD levels.
The clinical diagnosis of hypersensitivity to the food dye tartrazine in 16 subjects correlated with levels of tartrazine-specific IgD antibodies determined by a solid phase radioimmunoassay inhibition test. This is the first study associating hypersensitivity to a low molecular weight chemical with an antibody response of the IgD class. There was little or no correlation between clinical sensitivity and IgE antibodies.
D000917:Antibody Formation; D000918:Antibody Specificity; D001391:Azo Compounds / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000276:immunology*; D006801:Humans; D007072:Immunoglobulin D; D013645:Tartrazine / Q000009:adverse effects*
D001391:Azo Compounds; D007072:Immunoglobulin D; D013645:Tartrazine