[Reduced radiation sensitivity of hyperthyroid goiter with endocrine ophthalmopathy (author's transl)].
The therapeutic success of fractionated radioiodine treatment of hyperthyroid patients with and without endocrine ophthalmopathy is examined. To achieve a stable euthyroid metabolism, patients with endocrine ophthalmopathy generally need a greater number of treatments with a necessarily higher total dose of radioiodine and longer duration of treatment than hyperthyroid patients without endocrine ophthalmopathy. The average age, the average uptake of 131l and the serum concentration of free T4 were comparable in both groups of patients. A struma nodosa was more frequently found in the group of hyperthyroid patients with endocrine ophthalmopathy than in hyperthyroid patients without exophthalmus.
D004307:Dose-Response Relationship, Radiation; D005260:Female; D006044:Goiter, Nodular / Q000150:complications; D006111:Graves Disease / Q000150:complications*; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications / Q000532:radiotherapy*; D007455:Iodine / Q000008:administration & dosage / Q000378:metabolism; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011836:Radiation Tolerance; D011879:Radiotherapy Dosage; D013974:Thyroxine / Q000097:blood
D007457:Iodine Radioisotopes; D007455:Iodine; D013974:Thyroxine
Verminderte Strahlensensibilität hyperthyreoter Strumen bei endokriner Ophthalmopathie.