Grand mal seizures after retrobulbar block.
Convulsions developed in two patients after retrobulbar block. The amount of local anesthetic agent that was used was considerably less than the intravenous toxic dose in both cases. No retrobulbar hemorrhage resulted. The probable cause of seizures was inadvertent injection of local anesthetic directly to the CNS via the ophthalmic artery or its sheath.
D000368:Aged; D000772:Anesthesia, Local / Q000009:adverse effects; D002045:Bupivacaine / Q000009:adverse effects*; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced*; D004837:Epinephrine / Q000009:adverse effects; D005123:Eye / Q000294:innervation; D006801:Humans; D007269:Injections, Intra-Arterial / Q000009:adverse effects; D008012:Lidocaine / Q000009:adverse effects*; D008297:Male; D009407:Nerve Block / Q000009:adverse effects*; D009880:Ophthalmic Artery; D012163:Retinal Detachment / Q000601:surgery*; D012591:Scleral Buckling
D008012:Lidocaine; D002045:Bupivacaine; D004837:Epinephrine