Refractory sideroblastic anemia secondary to autoimmune hemolytic anemia.
A 75-year-old woman was hospitalized with autoimmune hemolytic anemia. During a period of 22 months the patient had six hemolytic crises which responded to treatment with prednisone and azathioprine. During the last admission the patient presented a sideroblastic anemia with 98% of 'ring sideroblasts' in the bone marrow. This association has never, to our knowledge, been reported before. It is possible that the immunosuppression played a definite role in the development of this sideroblastic anemia.
D000368:Aged; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications* / Q000188:drug therapy; D000756:Anemia, Sideroblastic / Q000209:etiology*; D001379:Azathioprine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy; D011241:Prednisone / Q000627:therapeutic use
D001379:Azathioprine; D011241:Prednisone