Ethanol induced secretion of calcitonin in chronic renal disease.
Whisky (25-50 ml) increased plasma levels of immunoreactive calcitonin (iCT) in seventeen of nineteen patients with chronic renal failure. The effect was greater in patients with high levels of iCT than in those with normal levels. Changes in plasma iCT were not related to changes in calcium, phosphate or immunoreactive gastrin, but were inhibited by the prior administration of propranolol.
D002116:Calcitonin / Q000378:metabolism*; D002118:Calcium / Q000097:blood; D000431:Ethanol; D005755:Gastrins / Q000097:blood; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism*; D010281:Parathyroid Hormone / Q000378:metabolism; D010710:Phosphates / Q000097:blood; D011433:Propranolol; D011863:Radioimmunoassay
D005755:Gastrins; D010281:Parathyroid Hormone; D010710:Phosphates; D000431:Ethanol; D002116:Calcitonin; D011433:Propranolol; D002118:Calcium