Correlations between anti-albumin antibodies and HBsAG in hepatic patients.
A new category of autoantibodies--antipolymerized albumin antibodies (AAA)--was discovered in 1974. Studies performed from 1974 to 1976 showed their diagnosis and prognostic values in hepatic diseases; the AAA tests [immunodiffusion (ID) and hemagglutination (HS)] made possible a good estimation of the total liver cell function. Without being specific for a viral hepatitis B infection, highly significant linear correlations were found for AAA precipitin and agglutinin positivities with presence of HBsAg. High titre of AAA agglutinins unaccompanied by a positive ID test, characterise the "healthy carrier" of the HBsAg, while the isolated AAA positivity in ID is met in more severe, long-standing hepatic diseases.
D000208:Acute Disease; D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D002648:Child; D002908:Chronic Disease; D006386:Hemagglutination Tests; D006505:Hepatitis / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006525:Hepatitis, Viral, Human / Q000276:immunology; D006801:Humans; D005779:Immunodiffusion; D008103:Liver Cirrhosis / Q000276:immunology; D008107:Liver Diseases / Q000276:immunology*; D008887:Military Medicine
D001323:Autoantibodies; D006514:Hepatitis B Surface Antigens