title: The effect of a synthetic polypeptide, threonyl-prolyl-arginyl-lysine, on ovulation in the squirrel monkey (Saimiri sciureus) and hamster.
abstract: Synthetic TPAL, a polypeptide reported to occur naturally in hamster zygotes, was tested at doses of 3 or 18 microgram/day for antiovulatory activity in cyclic hamsters (for 4 days) and squirrel monkeys (for 5 days) induced to ovulate. The TPAL treatment did not alter the ovulatory response in hamsters or monkeys.
mesh_terms: D000818:Animals; D006224:Cricetinae; D005260:Female; D000882:Haplorhini; D009842:Oligopeptides / Q000494:pharmacology*; D010060:Ovulation / Q000187:drug effects*; D012453:Saimiri
chemical_list: D009842:Oligopeptides; C017147:kentsin