Hypothesis on the mechanism of erythrocyte invasion by malaria merozoites.
Plasmodium knowlesi merozoites invade erythrocytes by a sequence of events: attachment, widespread deformation of the erythrocyte membrane, endocytosis, and resealing of the membrane and vesicle. The possible mechanisms by which these events occur are discussed. In particular, there is a detailed discussion of the role of the Duffy blood group system in invasion.
D000268:Adhesiveness; D000818:Animals; D002462:Cell Membrane; D004375:Duffy Blood-Group System; D004912:Erythrocytes / Q000469:parasitology*; D000882:Haplorhini; D006801:Humans; D008253:Macaca mulatta; D008954:Models, Biological; D010961:Plasmodium / Q000502:physiology*; D010963:Plasmodium falciparum / Q000502:physiology; D010966:Plasmodium vivax / Q000502:physiology
D004375:Duffy Blood-Group System