The effect of orally administered sodium cromoglycate on symptoms of food allergy.
A comparison was made between the effects of sodium cromoglycate (SCG) and placebo on symptoms of food allergy in twenty children. Both the clinician's and patient's preferences and the clinician's evaluation of the specific response to challenge showed a significant benefit from SCG. A striking effect on skin symptoms was seen in some children and the recorded mean score for skin symptoms was lower after 2 weeks' treatment with sodium cromoglycate. However, the differences detected from the mean symptom scores were not statistically significant. Neither were there any significant changes in the IgE, IgG, IgA and IgM food allergen antibody levels related to the treatment.
D000293:Adolescent; D000485:Allergens; D000818:Animals; D001249:Asthma; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004205:Cromolyn Sodium / Q000627:therapeutic use*; D004485:Eczema; D005260:Female; D005399:Fishes / Q000276:immunology; D005512:Food Hypersensitivity / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A; D007073:Immunoglobulin E; D007075:Immunoglobulin M; D007223:Infant; D007782:Lactoglobulins / Q000276:immunology; D008297:Male; D010059:Ovomucin / Q000276:immunology; D010342:Patient Acceptance of Health Care; D010919:Placebos; D011852:Radioallergosorbent Test; D011864:Radioimmunosorbent Test
D000485:Allergens; D007070:Immunoglobulin A; D007075:Immunoglobulin M; D007782:Lactoglobulins; D010919:Placebos; D010059:Ovomucin; D007073:Immunoglobulin E; D004205:Cromolyn Sodium