title: Effects of castration, estradiol and testosterone on tubulin levels of the medial basal hypothalamus and the adenohypophysis of the rat.
abstract: Tubulin levels of the medial basal hypothalamus (MBH) were greater in male than in female rats. Orchidectomy brought about a decrease of MBH tubulin concentration, whereas testosterone injection augmented it in the MBH and adenohypophysis. Estradiol administration augmented MBH tubulin and protein concentration.
mesh_terms: D000818:Animals; D002369:Castration; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D006023:Glycoproteins / Q000378:metabolism*; D007031:Hypothalamus / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D010903:Pituitary Gland, Anterior / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D012737:Sex Factors; D013739:Testosterone / Q000494:pharmacology*; D014404:Tubulin / Q000378:metabolism*
chemical_list: D006023:Glycoproteins; D014404:Tubulin; D013739:Testosterone; D004958:Estradiol