Protein deficiency and energy restriction in young cebus monkeys.
Infant cebus monkeys (Cebus albifrons) were fed liquid formulas that were limited in protein, energy, or a combination of the two restrictions. Weight gain, food intake, hematological development, and plasma protein and cholesterol levels were monitored over a 20-week period. The animals restricted in protein developed the classical signs of protein deficiency--reductions in plasma albumin, a mild anemia, accumulation of fat in the liver, and, in a few cases, facial edema. These animals maintained a relatively high energy intake, and apparently wasted energy when compared to similarly non-growing energy-restricted animals. Energy-restricted animals did not exhibit these symptoms, even when their daily protein intake was reduced to match that of protein-restricted monkeys. It is concluded that an energy restriction superimposed upon a limited protein intake did not increase protein requirements or precipitate protein deficiency.
D000596:Amino Acids / Q000097:blood; D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism; D001798:Blood Proteins / Q000378:metabolism; D001823:Body Composition; D002784:Cholesterol / Q000097:blood; D004195:Disease Models, Animal; D004487:Edema / Q000209:etiology; D002149:Energy Intake; D004734:Energy Metabolism; D006128:Growth; D000882:Haplorhini; D006400:Hematocrit; D011488:Protein Deficiency / Q000378:metabolism; D011502:Protein-Energy Malnutrition / Q000097:blood / Q000378:metabolism*
D000596:Amino Acids; D001798:Blood Proteins; D002784:Cholesterol