Cornifying Darier's disease.
Five patients with cornifying Darier's disease were treated successfully by partial-thickness resection of the skin and dermabrasion down through the papillary dermis into the reticular dermis. Healing was quick and the complication rate was low. Although some lesions recurred, all of these 5 patients have been able to return to full work and are now employed. The histology and genetics of the disease are discussed.
D000328:Adult; D007644:Darier Disease / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D003869:Dermabrasion; D006801:Humans; D008297:Male; D008875:Middle Aged; D013518:Surgery, Plastic / Q000379:methods*