Generation of reactive metabolites of N-hydroxy-phenacetin by glucoronidation and sulfation.
D000081:Acetamides / Q000378:metabolism; D000818:Animals; D005965:Glucuronates / Q000378:metabolism; D014453:Glucuronosyltransferase / Q000378:metabolism; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D008297:Male; D010615:Phenacetin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology; D011485:Protein Binding; D051381:Rats; D013329:Structure-Activity Relationship; D013431:Sulfates / Q000378:metabolism; D013466:Sulfurtransferases / Q000378:metabolism; D013696:Temperature; D013997:Time Factors
D000081:Acetamides; D005965:Glucuronates; D013431:Sulfates; D014453:Glucuronosyltransferase; D013466:Sulfurtransferases; D010615:Phenacetin