Late development of colorectal cancer subsequent to pelvic irradiation.
Two cases of irradiation-associated carcinoma of the colon are reported and the literature reviewed. The clinical courses and operative difficulties in treating these patients are emphasized. The necessity for life-long follow-up examinations with proctoscopic and barium-enema evaluations in high-risk patients is stressed. Irradiation-associated carcinoma of the colon occurs almost exclusively in women, but should be investigated in patients of either sex who live for long periods after pelvic irradiation.
D000230:Adenocarcinoma / Q000473:pathology / Q000532:radiotherapy; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy; D003110:Colonic Neoplasms / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D011832:Radiation Injuries; D011839:Radiation, Ionizing / Q000009:adverse effects; D012004:Rectal Neoplasms / Q000209:etiology* / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000532:radiotherapy