Influence of cytostatics on some platelet functions in vitro. V. Hydroxyurea.
Hydroxyurea added to citrated platelet-rich plasma in vitro did not influence the aggregation of the platelets, their adhesion to glass, their release of aggregating activity, platelet factor 4 or availability of platelet factor 3. Neither did it have any effect on the uptake of 14C-serotonin, the reptilase clot retraction or the coagulation system.
D001792:Blood Platelets / Q000187:drug effects*; D006801:Humans; D006918:Hydroxyurea / Q000494:pharmacology*; D010973:Platelet Adhesiveness / Q000187:drug effects; D010974:Platelet Aggregation / Q000187:drug effects; D010977:Platelet Factor 3; D010978:Platelet Factor 4; D012701:Serotonin / Q000097:blood
D012701:Serotonin; D010977:Platelet Factor 3; D010978:Platelet Factor 4; D006918:Hydroxyurea