[Micromethod of preparing and purifying labeled 4-methyl-5-beta-hydroxyethylthiazole].
A micromethod is developed for production and purification of small amounts (50-60 microgram) of 35S-4-methyl-5beta-hydroxyethyl thiazole(hemineurine)--a neurotropic agent, which is promising for treatment of delirium tremens. 35S-hemineurine was obtained as follows: sulfite separation of it from pyrimidine residues and other reagents py paper electrophoresis and the subsequent elution of labelled 4-methyl-5beta-hydroxyethyl thiazole from electrophoregramms. The purity of the preparation obtained was controlled by chromatographic, chemical and spectrophotometric analysis (using pure unlabelled preparation).
D001249:Asthma / Q000150:complications; D001991:Bronchitis / Q000150:complications; D006993:Hypnotics and Sedatives; D013831:Thiamine / Q000032:analysis; D013844:Thiazoles / Q000302:isolation & purification*; D014149:Tranquilizing Agents
D006993:Hypnotics and Sedatives; D013844:Thiazoles; D014149:Tranquilizing Agents; D013831:Thiamine
Mikrometod polucheniia i ochistki mechenogo 4-metil-5 beta-oksiétiltiazola.