A positive feedback effect of oestradiol on LH release in the male marmoset monkey, Callithrix jacchus.
Subcutaneous injections of oestradiol benzoate in oil, resulting in a sustained elevation of circulating oestradiol levels, induced an initial suppression of LH secretion, followed by a positive discharge of LH in castrated male and female and in intact male marmosets. Oestrogen-induced LH release (producing maximum LH concentrations 24 h after the injection) was observed in 75% of castrated males and females. A positive discharge of LH occurred in 50% of intact males 28-36 h after oestrogen administration.
D000818:Animals; D002143:Callitrichinae; D002369:Castration; D004958:Estradiol / Q000097:blood / Q000494:pharmacology*; D005246:Feedback; D005260:Female; D000882:Haplorhini; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism*; D008297:Male
D004958:Estradiol; D007986:Luteinizing Hormone