Monoclonal gammopathies in rheumatoid arthritis.
A total of 2560 sera from patients with and without rheumatoid diseases were examined for the incidence of monoclonal proteins. The incidence of monoclonal protein was higher (3.3%) in patients with rheumatoid arthritis than with other non-rheumatoid diseases of connective tissue (0.7%). Of 16 monoclonal proteins found in rheumatoid arthritis, 15 were IgG and 1 IgA; 7 sera belonged to the kappa and 9 to lambda type.
D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000276:immunology; D004587:Electrophoresis, Agar Gel; D004590:Electrophoresis, Paper; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains; D008875:Middle Aged
D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains