title: The effects of a polychlorinated biphenyl)Aroclor 1254) on the white pelican: ultrastructure of hepatocytes.
abstract: White pelicans were each given 100 mg of polychlorinated biphenyls (Aroclor 1254) per day for 10 weeks. After the treatment period, the bird's food supply was decreased 50% for 2 weeks. Measurements taken from transmission electron micrographs of the pelican's liver tissue revealed hepatocytes of the treated birds averaged 22% larger in cross-section area than those of controls. The number of vacuoles (lysosomes, microbodies) per hepatocyte was 22% greater. The number of mitochondria per hepatocyte was 25% greater while 25% fewer cristae per mitochondrion were present in treated as compared to control birds.
mesh_terms: D000818:Animals; D001140:Aroclors / Q000494:pharmacology*; D001717:Birds / Q000033:anatomy & histology*; D008099:Liver / Q000187:drug effects / Q000648:ultrastructure*; D008930:Mitochondria, Liver / Q000187:drug effects; D011078:Polychlorinated Biphenyls / Q000494:pharmacology*
chemical_list: D001140:Aroclors; D011078:Polychlorinated Biphenyls