title: Carcinomas of the paranasal sinuses: a study of sixty-six cases.
abstract: The therapy records of 66 patients with carcinomas of the paranasal sinuses were reviewed; primary carcinomas occurred in the maxillary sinus in 50 patients, the ethmoid sinus in 11 patients, the sphenoid sinus in 4 patients and the frontal sinus in 1 patient. The tumors of the maxillary sinus were staged retrospectively according to the American Joint Committee staging system recommended in 1976; 1 of 2 patients with T1, 5 of 11 patients with T2, 10 of 34 patients with T3 and 1 of 3 patients with T4 lesions showed no evidence of disease (NED) at 3 years. Combined high dose irradiation (6,000 rads in 6 weeks) followed by radical surgery in 4 to 6 weeks was well tolerated; this approach is recommended for the treatment of T1, T2, and selected T3-4 maxillary sinus lesions. Only 2 of 11 patients with ethmoid sinus lesions survived at 3 years.
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D002295:Carcinoma, Transitional Cell / Q000628:therapy*; D005005:Ethmoid Sinus; D005260:Female; D005626:Frontal Sinus; D006801:Humans; D008207:Lymphatic Metastasis / Q000628:therapy; D008297:Male; D008443:Maxillary Sinus; D008875:Middle Aged; D010255:Paranasal Sinus Neoplasms / Q000628:therapy*; D011882:Radiotherapy, High-Energy; D012075:Remission, Spontaneous; D013101:Sphenoid Sinus; D013997:Time Factors