title: [Creatinine clearance: indirect estimate (author's transl)].
abstract: The validity of some formulas proposed to estimate the creatunine clearance by values of serum creatinine and others non analytical parameters (sex, age, weight and height) was tested in a group of 200 adults (100 males and 100 females) and in a group of 134 children (80 males and 54 females). The age ranged from 1 month to 78 years; the values of serum creatinine varied from 0.3 to 10.0 mg/dl; the clearance value was calculated also in the usual way by the AutoAnalyzer (N-11 a Technicon method). The statistical analysis and the comparison of the data show good correlation between the clearance values calculated either by the direct or the indirect method. However the frequency of inacceptable disagreements does not allow the use of these formulas to evaluate the renal function and to regulate the administration of some drugs.
mesh_terms: D000328:Adult; D000367:Age Factors; D001322:Autoanalysis; D001827:Body Height; D001835:Body Weight; D002648:Child; D003404:Creatinine / Q000032:analysis / Q000097:blood*; D005260:Female; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D012737:Sex Factors
chemical_list: D003404:Creatinine
vernacular_title: Creatinina clearance: calcolo indiretto.