[Effects of hypothalamus and globus pallidus lesions and of apomorphine injections into the globus pallidus, caudate nucleus, substantia nigra and septum on the aggressive behavior induced by apomorphine treatment of rats (author's transl)].
Intraspecific apomorphine-induced aggressive behavior in the rat was not affected following electrolytic lesions of the ventromedial hypothalamus. Some inhibition of the aggressive behavior was found after lateral lesions and an almost total suppression after destruction of globus pallidus. These results, as well as those following localized injections of apomorphine into the septum, substantia nigra, caudate nucleus, and globus pallidus suggested that the latter anatomical region may be the major site of the action of apomorphine in the behavior studies. The role of acetylcholine is discussed.
D000374:Aggression / Q000187:drug effects*; D000818:Animals; D001058:Apomorphine / Q000008:administration & dosage / Q000494:pharmacology*; D002421:Caudate Nucleus; D005917:Globus Pallidus / Q000502:physiology*; D006801:Humans; D007031:Hypothalamus / Q000502:physiology*; D007276:Injections, Intraventricular; D051381:Rats; D013378:Substantia Nigra
D001058:Apomorphine
Effets de lésions de l'hypothalamus et du globus pallidus et d'injections d'apomorphine dans le globu pallidus, le noyau caudé, la substantia nigra et le septum sur le "comportement d'agressivité induit par l'apomorphine" chez le rat.