[Inhibitory effect of exogenous histones on cellular growth and DNA synthesis in Chlamydomonas reinhardtii].
The addition of exogenous histones to synchronous culture of Chlamydomonas reinhardtii, at the beginning of the cell cycle, leads to the death of the cells. The same amount of histones added in the middle of the cycle, only blocks the cell division. The mechanism of this inhibition effect of the histones could involve a block at the level of the chloroplast DNA replication.
D002453:Cell Cycle / Q000187:drug effects; D002696:Chlamydomonas / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D002736:Chloroplasts / Q000378:metabolism; D004247:DNA / Q000096:biosynthesis*; D004261:DNA Replication / Q000187:drug effects; D006657:Histones / Q000494:pharmacology*
D006657:Histones; D004247:DNA
Action inhibitrice des histones exogénes sur la croissance cellulaire et sur la synthése d' ADN chez Chlamydomonas reinhardtii.