title: Interrelationship of Chlamydia trachomatis and other pathogens in the female genital tract.
abstract: The isolation of Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, and Candida albicans in the female genital tract was studied in 1323 patients attending a venereal disease clinic. Disruption of the cell monolayers use for the isolation of C. trachomatis was significantly associated with the presence of T. vaginalis; this effect was markedly reduced by the addition of vancomycin to gentamicin and amphotericin B in the transport and growth media. The only significant positive association was the more frequent isolation of C. trachomatis in the presence of N. gonorrhoeae. There was a negative association between N. gonorrhoeae and C. albicans and between T. vaginalis and C. albicans, the fungus being isolated significantly less frequently when these microorganisms were present.
mesh_terms: D002176:Candida albicans / Q000302:isolation & purification; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D005260:Female; D005836:Genitalia, Female / Q000382:microbiology*; D006801:Humans; D009344:Neisseria gonorrhoeae / Q000302:isolation & purification; D014246:Trichomonas vaginalis / Q000302:isolation & purification