title: [Monocytic leukemia. Analysis of clinical and hematological data in 21 patients (author's transl)].
abstract: A clinical hematological survey is given of 21 patients with monocytic leukemia. About 1/3 of all immature cell leukoses are monocytic leukemias; a classification of the acute leucoses by enzyme histochemical methods should be attempted. Since more than half of the patients exhibited subleukemic to aleukemic peripheral leukocyte levels, the histological findings of a sternal puncture are diagnostic pointers. The bone marrow picture of monocytic leukemia is characterized by a great preponderance of atypical cell elements of the monocyte series which give a distinctly positive reaction in the non-specific esterase test. The combined use of cytostatics producing remission brought marked improvement in half the patients. Remission lasted from 2 to 8 weeks.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D001856:Bone Marrow Examination; D002908:Chronic Disease; D003561:Cytarabine / Q000008:administration & dosage; D003630:Daunorubicin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007951:Leukemia, Myeloid / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy / Q000201:enzymology; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009000:Monocytes / Q000473:pathology; D013249:Sternum; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D003561:Cytarabine; D014750:Vincristine; D004317:Doxorubicin; D008727:Methotrexate; D003630:Daunorubicin
vernacular_title: Monozyten-Leukämie. Analyse der Klinischen und hämatologischen Daten bei 21 Patienten.