[Effect of sigetin on the concentration of triglycerides and cholesterol in rat blood and liver].
It was shown in experiments on male rats that sygethin an analogue of synesterol devoid of estrogenic effect decreased cholesterol level in the intact animals and diminished hypercholesterolemia induced by dexamethasone. Sygethin inhibited the hypertriglyceridemia induced by diethylstilbestrol, as well as by ethanol and dexamethasone.
D000818:Animals; D001557:Benzenesulfonates / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D002784:Cholesterol / Q000032:analysis* / Q000097:blood; D004054:Diethylstilbestrol / Q000008:administration & dosage; D045166:Estradiol Congeners / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D006949:Hyperlipidemias / Q000188:drug therapy*; D000960:Hypolipidemic Agents; D008099:Liver / Q000032:analysis*; D008297:Male; D051381:Rats; D014280:Triglycerides / Q000032:analysis* / Q000097:blood
D001557:Benzenesulfonates; D045166:Estradiol Congeners; D000960:Hypolipidemic Agents; D014280:Triglycerides; C001770:sigetin; D004054:Diethylstilbestrol; D002784:Cholesterol
Vliianie sigetina na soderzhanie triglitseridov i kholesterina v krovi i pecheni krys.