title: [Results of a double blind study with Segontin-Digoxin in coronary heart disease (author's transl)].
abstract: Segontin-Digoxin and digoxin were tested in a cross-over double blind trial in 30 patients with coronary heart disease and concomitant organic insufficiency in a cardiological specialist practice. As far as the coronary symptoms were concerned, treatment with Segontin-Digoxin was clearly superior to digoxin therapy alone. With regard to the elimination or improvement of signs of myocardial insufficiency, no difference could be established between the two preparations. A distinct lowering of heart rate and blood pressure, especially in hypertensives, was observed with Segontin-Digoxin therapy compared with digoxin alone.
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D003327:Coronary Disease / Q000150:complications / Q000188:drug therapy*; D004077:Digoxin / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D006333:Heart Failure / Q000150:complications; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos; D011299:Prenylamine / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D014149:Tranquilizing Agents
chemical_list: D004338:Drug Combinations; D010919:Placebos; D014149:Tranquilizing Agents; D004077:Digoxin; D011299:Prenylamine
vernacular_title: Ergebnisse einer Doppelblindstudie mit Segontin-Digoxin bei der koronaren Herzkrankheit