Anger camera imaging of perfused and nonperfused brain tissue with intra-arterial 133Xenon technique.
The regional cerebral blood flow, the regional blood flow distribution, and the regional distribution of perfused (= vital) brain tissue been imaged with a digitalized conventional Anger camer. An analog scaler was placed behind the PM-tubes to reduce dead-time loss. The input pulse rate was doubled to counteract the effect of scaling on counting statistics, and the gamma emission was filtered through 1 mm of brass to increase the fraction of the integral count rate within the 40% window. In this way the 31 keV peak disappears, and Compton scatter and disturbing coincidences are markedly reduced. This improves spatial resolution. The flow parameters are imaged regionally in 3 X 3 mm2 matrix elements after flat field correction and smoothing. The matrix is 64 X 64 interpolated to 128 X 128. Patient studies emphasized the importance of imaging the distribution of perfused and nonperfused tissue in cases of infarctions, dilacerations, etc., where angiography and conventional brain scanning may often be negative.
D000328:Adult; D000368:Aged; D001099:Arachnoid / Q000000981:diagnostic imaging; D001254:Astrocytoma / Q000000981:diagnostic imaging; D001927:Brain Diseases / Q000000981:diagnostic imaging*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging; D002561:Cerebrovascular Disorders / Q000139:chemically induced; D003288:Contusions / Q000000981:diagnostic imaging; D003560:Cysts / Q000000981:diagnostic imaging; D004828:Epilepsies, Partial / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000000981:diagnostic imaging; D008297:Male; D008614:Meperidine / Q000009:adverse effects; D008875:Middle Aged; D011247:Pregnancy; D011248:Pregnancy Complications / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging; D014980:Xenon Radioisotopes
D014980:Xenon Radioisotopes; D008614:Meperidine