Human autologous and allogeneic rosettes.
Human red blood cells can bind to human peripheral blood lymphocytes. The percentage of these rosette-forming cells (TEh) depends on various conditions including temperature and the use of selected foetal calf serum. It is improved by toluidine blue. Prior incubation at 37 degrees C is not necessary. ABO and rhesus antigen D have no influence on rosette formation. Analysis of human rosettes in T and B cell rich populations, in patients with chronic lymphatic leukaemia or T cell lymphoma provides further evidence that human autologous and allogeneic rosette-forming cells belong to a T cell subpopulation.
D000017:ABO Blood-Group System; D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D001782:Blood Donors; D002417:Cattle; D002469:Cell Separation; D005333:Fetus / Q000276:immunology; D006801:Humans; D007158:Immunologic Techniques; D012204:Rh-Hr Blood-Group System; D012710:Serum Albumin, Bovine / Q000494:pharmacology; D012756:Sheep; D013045:Species Specificity; D013601:T-Lymphocytes / Q000276:immunology; D013696:Temperature
D000017:ABO Blood-Group System; D012204:Rh-Hr Blood-Group System; D012710:Serum Albumin, Bovine