The formation of disulfide bonds in human protamines during sperm maturation.
The disulfide contents of human sperm heads, as measured by reduction to the sulfhydryls and subsequent alkylation with 14C-iodoacetamide, increase about 2-fold during the sperm passage from the caput to caudal epididymides. Majority of the increased disulfides resides in the human protamine fractions.
D002843:Chromatin / Q000648:ultrastructure; D004220:Disulfides; D004822:Epididymis / Q000378:metabolism; D006801:Humans; D008297:Male; D011479:Protamines / Q000378:metabolism*; D013079:Sperm Maturation
D002843:Chromatin; D004220:Disulfides; D011479:Protamines