Effect of cyproheptadine on TRH-stimulated prolactin and TSH release in man.
TRH-stimulated prolactin release was determined in four male volunteers with and without pre-treatment with cyproheptadine. All showed a marked increase in the TRH-mediated prolactin rise and a marked decrease in the TRH-mediated TSH rise when receiving cyproheptadine pre-treatment.
D000328:Adult; D003533:Cyproheptadine / Q000494:pharmacology*; D004357:Drug Synergism; D006801:Humans; D008297:Male; D011388:Prolactin / Q000097:blood*; D013972:Thyrotropin / Q000097:blood*; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology*
D003533:Cyproheptadine; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D013972:Thyrotropin