Isolation and properties of flagella of trypanosomatids.
A procedufe is described for the isolation of flagella of Crithidia fasciculata, Herpetomonas samuelpessoai and Leishmania tarentolae in a highly purified state and giving reasonably good yield. The 3 types of flagella give a similar electrophoretic pattern of proteins. It is shown that H. samuelpessoai and, to a lesser extent, C. fasciculata flagella confer protection against Trypanosoma cruzi infection.
D000818:Animals; D014355:Chagas Disease / Q000276:immunology; D056890:Eukaryota / Q000032:analysis* / Q000648:ultrastructure; D005407:Flagella / Q000032:analysis* / Q000648:ultrastructure; D006168:Guinea Pigs; D007891:Leishmania / Q000032:analysis / Q000648:ultrastructure; D011506:Proteins / Q000302:isolation & purification
D011506:Proteins