Malabsorption of water miscible vitamin A in children with giardiasis and ascariasis.
Vitamin A absorption was studied using a water-miscible oral preparation of vitamin A in 19 children ages 1 1/2 to 9 years old with giardiasis and/or ascariasis, both before and after their eradication with appropriate therapy, and in three children without parasites. Marked impairment of vitamin A absorption was noted when administered in a water miscible form in children with 1) combined infection with Giardia lamblia and Ascaris lumbricoides, 2) giardiasis alone, and 3) in a proportion of children with ascariasis alone. In children with both giardiasis and ascarasis eradication of the infections promptly lead to a significant improvement in vitamin A absorption and restored it to normal. Children with giardiasis alone also showed improved vitamin A absorption after therapy. In children with ascariasis alone successful therpay did not lead to a statistically significant improvement.
D001196:Ascariasis / Q000150:complications / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005873:Giardiasis / Q000150:complications / Q000378:metabolism*; D006801:Humans; D007408:Intestinal Absorption; D007583:Jejunum / Q000382:microbiology; D007785:Lactose / Q000378:metabolism; D050356:Lipid Metabolism; D008286:Malabsorption Syndromes / Q000188:drug therapy / Q000209:etiology; D008297:Male; D014801:Vitamin A / Q000378:metabolism* / Q000627:therapeutic use
D014801:Vitamin A; D007785:Lactose