[Morphogenesis of experimental emphysema induced by different circulation disorders in the lungs].
Pulmonary emphysema was reproduced in 126 rabbits by disorders of circulation in the pulmonary artery system with the development of pre- and postcapillary hypertension and hypovolemia of pulmonary circulation. Under conditions of pulmonary circulation hypertension changes in the lungs initially are of the compensatory-hypertrophic nature: hyperplasia and distention of capillaries, myoelastosis of respiratory bronchioles and closing plates of alveoli, hypertrophy of the muscle wall of arteries and veins. At later intervals (4--12 months), processes of atrophy, sclerosis and inflation develop in the lungs; changes in the lungs acquire the nature of emphysema. Anemia, parenchymal atrophy, sclerosis and inflation develop in the lungs due to a considerable reduction of circulation.
D000818:Animals; D001284:Atrophy; D002196:Capillaries / Q000473:pathology*; D006965:Hyperplasia; D006976:Hypertension, Pulmonary / Q000473:pathology*; D008168:Lung / Q000098:blood supply*; D011651:Pulmonary Artery / Q000473:pathology*; D011652:Pulmonary Circulation; D011656:Pulmonary Emphysema / Q000209:etiology*; D011817:Rabbits; D012598:Sclerosis
Morfogenez eksperimental'noĭ emfizemy, indutsirovannoĭ razlichnymi narusheniiami krovoobrashcheniia v legkikh.