GABA stimulates the rabbit corneal endothelial fluid pump.
GABA and its analogues were shown to activate the rabbit corneal endothelial fluid pump in the micromolar range. The stimulation was abolished by bicuculline and chlorpromazine, but not by picrotoxin.
D000818:Animals; D003315:Cornea / Q000166:cytology / Q000502:physiology*; D004727:Endothelium / Q000502:physiology; D011817:Rabbits; D013268:Stimulation, Chemical; D014882:Water-Electrolyte Balance / Q000187:drug effects*; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
D005680:gamma-Aminobutyric Acid