[Release of synthesized lipids by isolated Wistar rat liver perfused by labelled oleic acid and glycerol].
After perfusions with oleic acid (9, 10-3H) and glycerol (1-14C) of isolated livers from wistar Rats, previously subjected to fasting, the study of the TG and PL synthesized by the liver and released in the circulation gives of evidence similar ways of metabolising TG and PL. Two liver pools are present: -- a storage pool, built with slow exchanges of AG of endogenous glycerolipids. In our experiments, the TG: 16 : 0 18 : 1 18: 2 and 16 : 0 18 : 1 18 : 1 and the PL: PE and PC are the glycerolipids of liver constitution: -- a pool of liver secretion. TG and PL are formed according to a rapid de novo synthesis using preferentially the exogenous substrates. They are released in the circulation. In our experiments, the TG secreted are the TG 18 : 1 18 : 1 18 : 1 and 16 : 0 18 : 1 18 : 2, the PL are the PE, AP and LPC.
D000818:Animals; D005990:Glycerol / Q000378:metabolism*; D008055:Lipids / Q000096:biosynthesis*; D008297:Male; D009829:Oleic Acids / Q000378:metabolism*; D010743:Phospholipids / Q000096:biosynthesis; D051381:Rats; D014280:Triglycerides / Q000096:biosynthesis
D008055:Lipids; D009829:Oleic Acids; D010743:Phospholipids; D014280:Triglycerides; D005990:Glycerol
Sécrétion des lipides synthétisés par le foie de rat Wistar isoĺe et perfusé par de l 'acide oléique et du glycérol marqués.