The complications of full-pelvic irradiation with particular emphasis to external beam therapy.
62 Patients with uterine carcinoma of cervix treated with high-dose large-volume full-pelvic irradiation given through co-axial-opposing pair portals over the anterior and posterior pelvis. Of these patients, 29 also received a single course of intracavitary radium supplementary to external beam irradiation. Only the severe complications which required surgical intervention have been analyzed, In the group of 33 patients who received only external irradiation, 4 developed such complications (12.1%).The overall incidence of those complications was about 19.3%. It is concluded that the treatment with hidh-dose large-volume full-pelvic irradiation technique, utilizing two opposing parallel pelvic portals, carries an incidence of morbidity 3-4 times the acceptable level and should be discouraged. Alternative techniques are discussed.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000209:etiology*; D007415:Intestinal Obstruction / Q000209:etiology; D007416:Intestinal Perforation / Q000209:etiology; D007421:Intestine, Small / Q000528:radiation effects; D008875:Middle Aged; D009336:Necrosis; D010388:Pelvis; D011349:Proctitis / Q000209:etiology; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy / Q000009:adverse effects*; D013997:Time Factors; D014456:Ulcer / Q000209:etiology; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*