Evidence for a set of closely linked autosomal genes that interact with sex-chromosome heterochromatin in Drosophila melanogaster.
It is proposed that there exists a special region in the euchromatin of the left arm of chromosome 2 (contained within sections 31-32 of the standard salivary gland chromosome map) that is defined by a set of genes, each one of which interacts with a specific sex-chromosome heterochromatic segment. The evidence for the existence of this region is, first, the exhibition, mapping, and analysis of five different maternal-effect, embryonic semi-lethals located in region 31-32. Secondly, in each case the consequence of the maternal effect is markedly influenced by the amount of X- or Y-chromosome heterochromatin carried by the progeny of mutant mothers. The nature of this interaction and possible reasons for the existence of the cluster of autosomal genes are discussed.
D000818:Animals; D002874:Chromosome Mapping; D004331:Drosophila melanogaster / Q000648:ultrastructure*; D005111:Extrachromosomal Inheritance; D005260:Female; D005796:Genes; D008040:Genetic Linkage; D006570:Heterochromatin; D008297:Male; D009154:Mutation; D010641:Phenotype; D012730:Sex Chromosomes
D006570:Heterochromatin