[Late sequelae of tuberculous meningitis].
The paper contains a clinico-morphological description of a case with late sequelae of treated tubercular meningitis. The patient at 7 years of age had tuberculous meningitis which was treated by suboccipital and endolumbar administration of streptomycin. Following 12 years, epileptical seizures ensued with an eventual gradual weakness in the extremities leading to profound spastic tetraparesis. During the last years of life contractures and stem symptoms developed. The morphological picture was characterized by posttuberculous fibrous leptomeningitis with an extensive internal hydrocephalus, universal sclerosis of the cerebral and spinal vessels, disseminated demyelinization in the spinal cord and brain, a distinct improverishment of the grey matter by ganglionic cells. The result of liquorohemodynamical disorders was a syringolike cavity in the spinal cord. Under the ependima of the laral ventricle calcified cholesteatomas were found, which are considered as complications of suboccipital punctures in administering streptomycin.
D000328:Adult; D001921:Brain / Q000473:pathology*; D006801:Humans; D008297:Male; D008578:Meninges / Q000473:pathology*; D013116:Spinal Cord / Q000473:pathology*; D014390:Tuberculosis, Meningeal / Q000473:pathology*
Otdalennye posledstviia tuberkuleznogo meningita.