title: Comparative study of chromogenesis and endotoxin production from pathogenic Pseudomonas aeruginosa strains, isolated from neoplastic processes.
abstract: Several differences in relation to the chromogenesis and the production of endotoxins were found in Ps. aeruginosa strains, isolated from tumors. The strains isolated from neoplastic processes showed a higher amount of chromogenic fractions as compared with the control strains. Phenazinic compounds presented the main differences. Using two common methods of isolation and purification of Gram-negative endotoxin, we found a higher yield of these molecules in the case of tumor-isolated strains.
mesh_terms: D000818:Animals; D004731:Endotoxins / Q000096:biosynthesis* / Q000633:toxicity; D006801:Humans; D007928:Lethal Dose 50; D008070:Lipopolysaccharides / Q000096:biosynthesis / Q000633:toxicity; D051379:Mice; D009369:Neoplasms / Q000382:microbiology* / Q000532:radiotherapy; D010619:Phenazines / Q000378:metabolism; D010860:Pigments, Biological / Q000096:biosynthesis*; D011135:Polysaccharides, Bacterial / Q000096:biosynthesis / Q000633:toxicity; D011550:Pseudomonas aeruginosa / Q000378:metabolism*; D011817:Rabbits; D013045:Species Specificity
chemical_list: D004731:Endotoxins; D008070:Lipopolysaccharides; D010619:Phenazines; D010860:Pigments, Biological; D011135:Polysaccharides, Bacterial