[Cellular differentiation and malignant transformation (author's transl)].
The mechanisms and determination of differentiation of normal and cancer cells were compared by distinguishing them from the phenomena of regulation, retrodifferentiation and maturation. Reference is made to the laws of order in time and space which are superimposed on the common genetic code during the various types of differentiation. In conclusion, the particular mechanisms of malignant differentiation are discussed by taking melanoma and tumor formation by papova-viruses as examples.
D000818:Animals; D002454:Cell Differentiation; D002471:Cell Transformation, Neoplastic; D002472:Cell Transformation, Viral; D006801:Humans; D009858:Oncogenic Viruses / Q000235:genetics; D014176:Protein Biosynthesis; D013997:Time Factors; D014158:Transcription, Genetic
Différenciation cellulaire et cancérisation.