Binding of deoxyribonucleic acid to the surface of human platelets.
It was demonstrated that washed human platelets can bind minute amounts of 14C-DNA on their surface during short-term incubation. The binding was specific and firm in the described experimental conditions. Washed platelets bound also 14C-DNA anti-DNA antibody complexes, although to a lesser amount than 14C-DNA alone. The possible significance of these findings is briefly discussed.
D001665:Binding Sites; D001792:Blood Platelets / Q000378:metabolism*; D004247:DNA / Q000097:blood*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood
D004247:DNA