[Establishment and characterization of 3 human cell lines derived from intracerebral metastatic tumors].
Twelve human tumors were cultivated in vitro by the trypsinization technique and 3 cell lines were established. Each of these 3 lines showed individual characteristics which were maintained during passages. After inoculation into nude mice, 2 lines induced tumors which possessed the histologic features of the original human tumors (melanoma and carcinoma of stomach), the other line derived from a breast carcinoma was rejected.
D000818:Animals; D001932:Brain Neoplasms / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology; D002277:Carcinoma / Q000473:pathology; D002460:Cell Line; D003896:Desmosomes / Q000648:ultrastructure; D006801:Humans; D008545:Melanoma / Q000473:pathology; D051379:Mice; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D012878:Skin Neoplasms / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology; D014183:Transplantation, Heterologous
Etablissement et caractérisation de 3 lignées cellulaires humaines dérivées de tumeurs métastatiques intracérébrales