Antibacterial effects of metrizoate and metrizamide on bacterial growth in vitro.
Urinary pathogens were exposed in vitro to Isopaque and Amipaque in concentrations of 100 mg I/ml and 260 mg I/ml. Both contrast media in the higher concentration had a slight or negligible bacteriostatic effect on some of the test bacteria. No bactericidal effect was detected. Consequently, radiography of the urinary tract with these two media in the concentrations mentioned does not interfere with the culturing of bacteria from urine samples.
D001419:Bacteria / Q000187:drug effects*; D013293:Enterococcus faecalis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D007463:Iodobenzoates / Q000494:pharmacology*; D008793:Metrizamide / Q000494:pharmacology*; D008794:Metrizoic Acid / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D011514:Proteus vulgaris / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects
D007463:Iodobenzoates; D008794:Metrizoic Acid; D008793:Metrizamide