Treatment of luteal phase inadequacy with bromocriptine.
A group of 15 women diagnosed as having luteal phase inadequacy (LPI) and a history of 1--2 years of infertility were treated with bromocriptine continuously for 4 months. Plasma levels of prolactin, progesterone, 17 alpha-hydroxy-progesterone and estradiol were measured by radioimmunoassay in a control month and each of the treatment months. There was no significant improvement in the levels of the steroids over the 4-month period, although the prolactin levels were depressed, and 2 subjects became pregnant during the study.
D000328:Adult; D001971:Bromocriptine / Q000494:pharmacology / Q000627:therapeutic use*; D003338:Corpus Luteum / Q000187:drug effects / Q000503:physiopathology*; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D006908:Hydroxyprogesterones / Q000097:blood; D007247:Infertility, Female / Q000188:drug therapy* / Q000503:physiopathology; D008183:Luteal Phase / Q000187:drug effects*; D008598:Menstruation / Q000187:drug effects*; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D011863:Radioimmunoassay
D006908:Hydroxyprogesterones; D001971:Bromocriptine; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin