[Diabetic cataract and flavonoids (first results) (author's transl)].
The possible effects of Quercetine, a potent inhibitor of aldose-reductase, on cataract formation and vascular permeability were investigated in streptozotocine-diabetic rats. Preliminary results after peroral administration of Quercetine did not allow to demonstrate a clear inhibitory effect on cataract formation.
D000449:Aldehyde Reductase / Q000037:antagonists & inhibitors; D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects; D002386:Cataract / Q000517:prevention & control*; D003921:Diabetes Mellitus, Experimental / Q000150:complications; D003930:Diabetic Retinopathy / Q000517:prevention & control*; D005419:Flavonoids / Q000627:therapeutic use*; D011794:Quercetin / Q000494:pharmacology / Q000627:therapeutic use*; D051381:Rats; D012160:Retina / Q000098:blood supply
D005419:Flavonoids; D011794:Quercetin; D000449:Aldehyde Reductase
Cataracte diabétique et flavonoïdes (premiers résultats).