title: Non-clostridial gas gangrene in the diabetic lower limb.
abstract: Three cases of non-clostridial gas gangrene in diabetic lower limbs are reported. This rare condition occurs only in diabetes with peripheral neuropathy and is invariably fatal unless treated surgically. The clinical picture is deceptive with a slow, but insidiously progressive course, and the late appearance of skin necrosis. Antibacterial therapy is ineffective in preventing death. A serious delay may be fostered by inconclusive bacteriological investigations. Urgent radical amputation is required to save the patient's life.
mesh_terms: D000328:Adult; D001442:Bacteroides Infections / Q000150:complications; D003013:Clostridium; D048909:Diabetes Complications; D013293:Enterococcus faecalis; D004927:Escherichia coli Infections / Q000150:complications; D005260:Female; D005738:Gas Gangrene / Q000382:microbiology*; D006801:Humans; D007866:Leg / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D013203:Staphylococcal Infections / Q000150:complications; D013290:Streptococcal Infections / Q000150:complications