title: [Effect of imazalil (1-(2-(2,4-dichlorophenyl)-2-(2-propenyloxy) ethyl)-1H-imidazole) on biosynthesis of ergosterol in Penicillium expansum Link].
abstract: Imazalil is a new fungicide effective against Penicillium molds on fruits after harvest. This compound inhibits ergosterol biosynthesis in mycelia of Penicillium expansum. The accumulation of 24--methylenedithydrolanosterol, obtusifoliol and 14 alpha-methyl-delta 8, 24(28)-ergostadienol in treated fungi suggests that imazalil blocks sterol C--14 demethylation.
mesh_terms: D003640:Dealkylation; D004875:Ergosterol / Q000096:biosynthesis*; D005659:Fungicides, Industrial / Q000494:pharmacology*; D007093:Imidazoles / Q000494:pharmacology*; D010407:Penicillium / Q000187:drug effects / Q000378:metabolism*
chemical_list: D005659:Fungicides, Industrial; D007093:Imidazoles; D004875:Ergosterol
vernacular_title: Effet de l'imazalil [1-(2-(2,4-dichlorophényl)-2-(2-propényloxy) éthyl)-1H-imidazole] sur la biosynthèse de l'ergostérol chez Penicillium expansum Link.