Familial renal agenesis and urogenital malformations. Seminal vesicle cyst and vaginal cyst with bicornuate uterus in siblings.
A seminal vesicle cyst was found in a 30-year-old man with ipsilateral renal agenesis. His sister had embryologically analogous malformations--Gartner duct cyst, bicornuate uterus and renal agenesis. This seems to be the first reported familial occurrence of these combined malformations. The embryogenesis is reviewed and the diagnostic procedure and treatment are discussed.
D000015:Abnormalities, Multiple / Q000235:genetics; D000328:Adult; D003560:Cysts / Q000196:embryology / Q000235:genetics*; D005260:Female; D006801:Humans; D007668:Kidney / Q000002:abnormalities*; D008297:Male; D012669:Seminal Vesicles / Q000002:abnormalities*; D014599:Uterus / Q000002:abnormalities*; D014621:Vagina / Q000002:abnormalities*; D014928:Wolffian Ducts