Pheochromocytoma causing exercise-related headache and pulmonary edema.
A 13-year-old hypertensive girl with a history of severe headaches following exercise developed circulatory collapse after "squat jumps." Pulmonary edema was present without evidence of a cerebral mass. The patient died with increased intracranial pressure despite decompressive craniectomy. Neuropathological evaluation revealed diffuse cerebral edema and a pheochromocytoma in the right adrenal gland. Examination of urine revealed elevation of vanillylmandelic acid levels.
D000293:Adolescent; D001929:Brain Edema / Q000209:etiology; D005260:Female; D006261:Headache / Q000209:etiology*; D006801:Humans; D010673:Pheochromocytoma / Q000150:complications* / Q000473:pathology; D005082:Physical Exertion; D011654:Pulmonary Edema / Q000209:etiology*