Antibacterial and anthelminthic properties of visnaginone and khellinone derivatives.
The compounds tested, derivatives of visnaginone and khellinone, showed antibacterial activity on gram negative and gram positive micro-organisms. Some of the compounds possess an antibacterial activity on some pathogenic bacteria, i.e. Brucella abortus, for which there is no remedy as yet. All the chalcones tested were inactive except Ib, which showed antiparasitic broad spectrum.
D000818:Animals; D000871:Anthelmintics; D000900:Anti-Bacterial Agents; D001419:Bacteria / Q000187:drug effects; D001578:Benzopyrans / Q000494:pharmacology*; D002839:Chromans / Q000031:analogs & derivatives / Q000494:pharmacology*; D007666:Khellin / Q000031:analogs & derivatives* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests
D000871:Anthelmintics; D000900:Anti-Bacterial Agents; D001578:Benzopyrans; D002839:Chromans; D007666:Khellin