[Panniculitis nodularis febrilis non suppurative in metastasizing soft-tissue sarcoma].
Report of a 28-year-old female patient with a metastasizing soft tissue sarcoma confined to the oral mucosa and subcutis. The basic disease attracted clinical attention as a nodular febrile nonsuppurative panniculitis (Pfeifer-Weber-Christian disease). Perivascular tumor cells in the subcutis obviously induced localized fat necroses. Ultrastructurally, the pathological cells showed no indicative cytological characteristics other than a close association with reticulin fibers. Apparently, a metastasizing tumor disease can be concealed under the clinical picture of a nodular febrile non suppurative panniculitis--as a paraneoplastic syndrome.
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009061:Mouth Mucosa / Q000473:pathology*; D009062:Mouth Neoplasms / Q000175:diagnosis*; D009362:Neoplasm Metastasis; D010201:Panniculitis, Nodular Nonsuppurative / Q000175:diagnosis*; D009384:Paraneoplastic Endocrine Syndromes / Q000175:diagnosis; D012509:Sarcoma / Q000175:diagnosis*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis
Panniculitis nodularis febrilis non suppurativa bei metastasiertem Weichteilsarkom.