title: [Characteristics of glycogen synthetase I from rabbit skeletal muscles].
abstract: Electrophoretic heterogeneity of glycosynthetase I from rabbit skeletal muscles is observed. Multiple glycosynthetase forms are separated in sucrose density gradient, their molecular weights are estimated. The existence of the enzyme as an equilibrium system of oligomeric forms, capable of reversible association-dissociation, is demonstrated. Dissociating effect of ATP, high pH values (11--12) and high ionic strength (2 M KCl) on oligomers of glycogen synthetase I is found to take place. Different activity of oligomers of different association degree is observed.
mesh_terms: D000818:Animals; D006006:Glycogen Synthase / Q000378:metabolism; D007527:Isoenzymes / Q000378:metabolism; D007700:Kinetics; D046911:Macromolecular Substances; D008970:Molecular Weight; D009132:Muscles / Q000201:enzymology*; D009994:Osmolar Concentration; D011817:Rabbits
chemical_list: D007527:Isoenzymes; D046911:Macromolecular Substances; D006006:Glycogen Synthase
vernacular_title: Osobennosti stroeniia glikogensintetazy 1 iz skeletnykh myshts krolika.