title: [Results of a double blind study with segontin--digoxin in coronary heart disease. (author's transl)].
abstract: Segontin-Digoxin and digoxin were tested in a cross-over double blind trial in 30 patients with coronary heart disease and concomitant organic insufficiency in a cardiological specialist practice. As far as the coronary symptoms were concerned, treatment with Segontin-Digoxin was clearly superior to digoxin therapy alone. With regard to the elimination or improvement of signs of myocardial insufficiency, no difference could be established between the two preparations. A distinct lowering of heart rate and blood pressure, especially in hypertensives, was observed with Segontin-Digoxin therapy compared with digoxin alone.
mesh_terms: D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D003327:Coronary Disease / Q000175:diagnosis / Q000188:drug therapy*; D004077:Digoxin / Q000627:therapeutic use*; D004338:Drug Combinations; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011299:Prenylamine / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D004077:Digoxin; D011299:Prenylamine
vernacular_title: Erebnisse einer doppelblindstudie mit Segontin--digoxin bei der koronaren herzkrankheit