title: [Penetration of vaccinia virus through the mucosa of the small intestine and its dissemination in the body following enteric immunization of monkeys].
abstract: The authors studied the penetration of variolo-vaccine virus through the mucosa of the small intestine of Macacus rhesus in enteral immunization, by immunofluorescent and virological methods. Fifteen minutes after the immunization the variolo-vaccine virus was revealed at the surface of the mucosal prismatic epithelium and in the t. mucosa propria within the cytoplasm of cells of the macrophage type. Dissemination of the process with detection of the variolo-vaccine virus in the blood, the lymph nodes, spleen and liver was determined within the range of 1 to 3 hours.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D005455:Fluorescent Antibody Technique; D000882:Haplorhini; D007413:Intestinal Mucosa / Q000382:microbiology*; D008253:Macaca mulatta; D012900:Smallpox Vaccine / Q000008:administration & dosage*; D014616:Vaccinia virus / Q000502:physiology*
chemical_list: D012900:Smallpox Vaccine
vernacular_title: Proniknovenie virusa ospovaktsiny cherez slizistuiu obolochku tonkogo kishechnika i ego disseminatsiia v organizme pri énteral'noĭ immunizatsii obez'ian.