title: Multiple ocular anomalies associated with maternal LSD ingestion.
abstract: Severe ocular malformations, including microphthalmos, intraocular cartilage, cataract, persistent hyperplastic primary vitreous, and retinal dysplasia, occurred in a premature baby girl. The mother had ingested LSD during the first trimester of pregnancy. To our knowledge, this is the third case reported of ocular teratogenesis associated with maternal LSD ingestion. Further cases must be documented to establish an actual cause and effect relationship between the drug and the induced malformations.
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000473:pathology; D000015:Abnormalities, Multiple / Q000139:chemically induced* / Q000473:pathology; D000867:Anterior Chamber / Q000002:abnormalities; D002356:Cartilage / Q000002:abnormalities; D003315:Cornea / Q000002:abnormalities; D005123:Eye / Q000473:pathology; D005124:Eye Abnormalities; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008238:Lysergic Acid Diethylamide / Q000009:adverse effects*; D008431:Maternal-Fetal Exchange; D008850:Microphthalmos / Q000139:chemically induced; D009900:Optic Nerve / Q000002:abnormalities; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012160:Retina / Q000002:abnormalities; D013723:Teratogens; D014822:Vitreous Body / Q000002:abnormalities
chemical_list: D013723:Teratogens; D008238:Lysergic Acid Diethylamide