title: Covalent labeling of the tetrodotoxin receptor in excitable membranes.
abstract: A photoaffinity labeling technique is described by which a tetrodotoxin analog is covalently bound to receptor sites associated with the sodium pores of excitable membranes. The biological activity of the toxin analog is retained after the covalent binding reaction.
mesh_terms: D000345:Affinity Labels / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D002024:Bufo marinus; D008564:Membrane Potentials / Q000187:drug effects; D009132:Muscles / Q000378:metabolism*; D010777:Photochemistry; D011955:Receptors, Drug / Q000378:metabolism*; D013779:Tetrodotoxin / Q000031:analogs & derivatives / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D000345:Affinity Labels; D011955:Receptors, Drug; D013779:Tetrodotoxin