[Participation of the contractile activity of the skeletal musculature in systemic circulatory reactions to orthostatic action].
Under orthostatic test (OT) the elimination of the skeletal muscle contractile activity with a myorelaxant sharply elevated the initial hypotension and decreased considerably the compensatory restoration of the arterial pressure (AP) in anesthetized cats. Reaction of the cardiac output in OT changed insignificantly. The AP elevation synchronous with the motor reactions, eliminated by the myorelaxant, was observed. As revealed by the method of artificial circulation (bypass of the left ventricle), the compensatory vasoconstriction of the resistance vessels was eliminated by the myorelaxant under OT. In some experiments myorelaxation evoked a significant elevation of the blood pooling in the capacitance vessels.
D000818:Animals; D001775:Blood Circulation / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D002415:Cats; D006439:Hemodynamics / Q000187:drug effects; D009119:Muscle Contraction / Q000187:drug effects; D009132:Muscles / Q000098:blood supply / Q000502:physiology*; D011187:Posture; D013390:Succinylcholine / Q000494:pharmacology; D014655:Vascular Resistance / Q000187:drug effects
D013390:Succinylcholine
Uchastie sokratitel'noĭ aktivnosti skeletnoĭ muskulatury v sistemnykh reaktsiiakh krovoobrashcheniia na ortostaticheskoe vozdeĭstvie.