title: Biologic evaluation of filling materials. A comparison of results using cell culture techniques, implantation tests and pulp studies.
abstract: The paper presents a comparison of results from cell culture studies, implantation tests and pulp studies using silicate cement, composite material and zinc oxide/eugenol cement. The three techniques allow differentiation between reactions produced by the materials, but a poor correlation exists between the results from the different techniques. This information is considered important for a selection of techniques for biologic testing of dental materials.
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured / Q000187:drug effects* / Q000378:metabolism; D003188:Composite Resins / Q000494:pharmacology*; D003782:Dental Pulp / Q000187:drug effects*; D003793:Dental Restoration, Permanent; D062109:Dermatologic Surgical Procedures; D004341:Drug Evaluation; D000882:Haplorhini; D012823:Silicate Cement / Q000494:pharmacology*; D012867:Skin / Q000187:drug effects*; D015035:Zinc Oxide-Eugenol Cement / Q000494:pharmacology*
chemical_list: D001672:Biocompatible Materials; D003188:Composite Resins; D015035:Zinc Oxide-Eugenol Cement; D012823:Silicate Cement