[Alteration in the secretion of anterior pituitary hormones during dimethylbenzathracene induction of mammary tumors in rats].
In a sensitive strain of Rat (Sprague-Dawley) a deregulation of the secretion of some pituitary hormones was noted in the female during induction of mammary tumors by dimethylbenzanthracene administration. The deregulation occurred quickly and depended on the stage of the estrous cycle. It mainly consists of hyposecretion of gonadotropins. TSH and GH and of hypersecretion of prolactin.
D015127:9,10-Dimethyl-1,2-benzanthracene; D000818:Animals; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D013006:Growth Hormone / Q000378:metabolism; D007986:Luteinizing Hormone / Q000378:metabolism; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced / Q000378:metabolism*; D010908:Pituitary Hormones, Anterior / Q000378:metabolism*; D011388:Prolactin / Q000378:metabolism; D051381:Rats; D013972:Thyrotropin / Q000378:metabolism
D010908:Pituitary Hormones, Anterior; D015127:9,10-Dimethyl-1,2-benzanthracene; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D013006:Growth Hormone
Altération de la sécrétion des horomones antéhypophysaires deurant l'induction de tumeurs mammaires par le diméthylbenzanthracène chez la ratte.