Café-au-lait spots of the fundus in neurofibromatosis.
Mild pigmentary changes found in the fundi of two patients with neurofibromatosis, resembled café-au-lait spots homologous with skin manifestations of the disease. In one, associated retinal hamartomas were present. The café-au-lait lesions were clinically distinct from previously reported uveal melanomas and may represent a hitherto unrecognized sign of ocular neurofibromatosis.
D000328:Adult; D000368:Aged; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D009456:Neurofibromatosis 1 / Q000473:pathology*; D010858:Pigmentation; D012160:Retina / Q000473:pathology