Disappearance of chlorpromazine from plasma following drug withdrawal.
Plasma chlorpromazine measured by a gas chromatographic procedure was found to disappear rapidly during the first week after withdrawal of chlorpromazine treatment in a group of 17 chronically hospitalized patients. The drug or its metabolites were no longer measurable in plasma after 8 days.
D000328:Adult; D000368:Aged; D002746:Chlorpromazine / Q000097:blood* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008134:Long-Term Care; D008297:Male; D001523:Mental Disorders / Q000097:blood* / Q000188:drug therapy; D008657:Metabolic Clearance Rate; D008875:Middle Aged
D002746:Chlorpromazine