The inter-relationship of thyroid hormones, vitamin A and their binding proteins following acute stress.
The effects of surgical stress on the metabolism of the retinol-binding-protein-thyroxine-binding-prealbumin complex were investigated. The immediate postsurgical period was characterized by a rapid decline in the serum concentration of retinol, retinol binding protein and triiodothyronine and an increase in the 24 h urinary excretion of retinol, retinol-binding-protein and thyroxine. Similar, but less pronounced, changes were seen in other subjects suffering acute myocardial infarction but were not observed in normal healthy euthyroid males or in pre-operative euthyroid patients. The preparation of specific anti-retinol binding protein anti-serum and the use of this in 'monorocket' immunoelectrophoresis are also described.
D000906:Antibodies / Q000032:analysis; D006801:Humans; D009203:Myocardial Infarction / Q000378:metabolism; D011228:Prealbumin / Q000378:metabolism*; D012177:Retinol-Binding Proteins / Q000276:immunology / Q000378:metabolism* / Q000652:urine; D012709:Serum Albumin / Q000378:metabolism*; D013312:Stress, Physiological / Q000378:metabolism*; D013974:Thyroxine / Q000652:urine; D013975:Thyroxine-Binding Proteins / Q000378:metabolism*; D014284:Triiodothyronine / Q000097:blood; D014801:Vitamin A / Q000378:metabolism* / Q000652:urine
D000906:Antibodies; D011228:Prealbumin; D012177:Retinol-Binding Proteins; D012709:Serum Albumin; D013975:Thyroxine-Binding Proteins; D014284:Triiodothyronine; D014801:Vitamin A; D013974:Thyroxine