[Variation in the number and size of myelinated nerve fibers regenerated after repeated localized freezing of the sciatic nerve of rats].
The number and size of myelinated fibres have been determined in the nerve to medial head of the gastrocnemius muscle of Rats in which the sciatic nerve had been frozen locally 1 to 5 times at monthly intervals. The contralateral nerve was used as a control. When the measurements were made one month after the last freezing, the number of fibres increased progressively until the 3rd freezing, reaching about 220% of the normal value. No higher values were observed after 4 or 5 freezings. The mean diameter of fibres decreased with the number of operations. When the measurements were made 3, 6, 12 or 18 months after the 3rd freezing, the number of fibres decreased by about 30% between the 1st and the 3rd month and then stabilized. The mean diameter of fibres increased progressively. However, at the 18th month, the size of the myelinated fibres had not reached the normal value.
D000818:Animals; D005260:Female; D005615:Freezing; D008297:Male; D009413:Nerve Fibers, Myelinated / Q000166:cytology / Q000502:physiology*; D009416:Nerve Regeneration; D051381:Rats; D012584:Sciatic Nerve; D013997:Time Factors
Variations du nombre et du calibre des fibres nerveuses myélinisées régénérées après des congélations localisées itératives du nerf sciatique de rat.