Phagocytosis of chrysotile fibers by pleural mesothelial cells in culture.
Pleural mesothelial cells (PMC) from the parietal pleura of rats were incubated in culture with UICC A chrysotile fibers. The sequence of events in phagocytosis was studied by electron microscopy: phases of attachment sequestration, and degranulation of lysosomal content into the phagocytic vacuole were observed. This demonstrates that PMC can engage in phagocytosis of chrysotile fibers.
D000818:Animals; D001194:Asbestos; D002478:Cells, Cultured; D004847:Epithelial Cells; D008854:Microscopy, Electron; D010587:Phagocytosis; D010994:Pleura / Q000166:cytology*; D051381:Rats
D001194:Asbestos