title: Reaction time variability in epileptic and brain-damaged patients.
abstract: Median reaction times and intra-individual variability were studied in epileptic (N = 63), brain-damaged (non-epileptic) (N = 25) and control patients (N = 25) using a six and one half minute visual, continuous reaction time task. Epileptic and brain-damaged groups were significantly slower than control patients on median reaction times at the 10th, 50th, and 90th percentiles and on the differences between the 10th and 90th percentiles. Thus both general slowing and greater intra-individual variability were found in the epileptic and brain-damaged patients. Reaction times were not related to presence, type and severity of EEG abnormality or to age of onset of epilepsy. Grand mal patients did have significantly greater variability than other types of seizure patients. Epileptic and brain-damaged patients did not differ significantly on any reaction time variables. Both groups were discriminated significantly from the controls on all reaction time measures, especially on the intra-individual variability measure.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001925:Brain Damage, Chronic / Q000175:diagnosis / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000503:physiopathology; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000503:physiopathology; D004827:Epilepsy / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D004832:Epilepsy, Absence / Q000503:physiopathology; D004833:Epilepsy, Temporal Lobe / Q000503:physiopathology; D004830:Epilepsy, Tonic-Clonic / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time / Q000502:physiology*; D013997:Time Factors