Presence of sodium transport inhibiting factor in dog plasma during volume expansion.
Plasma dialysates from volume-expanded dogs (E) were compared directly to dialysates from the same dogs when hydropenic. In a double-blind study, E caused relative inhibition of short-circuit current in toad urinary bladder. We therefore confirm the presence of a sodium transport inhibiting factor in plasma of volume-expanded dogs.
D000818:Animals; D001681:Biological Assay; D001693:Biological Transport, Active; D001810:Blood Volume; D003681:Dehydration / Q000097:blood; D004285:Dogs; D012964:Sodium / Q000378:metabolism*; D014882:Water-Electrolyte Balance
D012964:Sodium