Cinnabarinate synthase from baboon (Papio ursinus) liver. Identity with catalase.
The enzyme chinnabarinate synthase was purified from the nuclei of baboon liver. Two purified fractions were obtained that exhibited a typical haem protein absorption spectrum; a probable identity with catalase was demonstrated. It was confirmed that catalase in the presence of Mn2+ produces cinnabarinate from 3-hydroxyanthranilate. Doubt is expressed on the existence of a distinct cinnabarinate synthase enzyme.
D015095:3-Hydroxyanthranilic Acid / Q000378:metabolism; D000818:Animals; D002374:Catalase / Q000302:isolation & purification*; D004591:Electrophoresis, Polyacrylamide Gel; D000882:Haplorhini; D008099:Liver / Q000201:enzymology*; D008345:Manganese; D010215:Papio / Q000378:metabolism*
D015095:3-Hydroxyanthranilic Acid; D008345:Manganese; C019901:cinnabarinate synthase; D002374:Catalase