Do peripheral nerves contain a factor inducing acetylcholine sensitivity in skeletal muscle?
A crude extract of the sciatic nerve, eluate of dialyzed nerve extract or 2 folin-positive sephadex fractions induced acetylcholine sensitivity of extrajunctional regions in extensor digitorum longus muscle fibres of the rat, when released from silastic plates implanted for 3--4 days onto the muscle surface.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D002454:Cell Differentiation; D004305:Dose-Response Relationship, Drug; D005260:Female; D008564:Membrane Potentials / Q000187:drug effects; D009045:Motor Endplate / Q000502:physiology*; D009469:Neuromuscular Junction / Q000502:physiology* / Q000648:ultrastructure*; D010525:Peripheral Nerves / Q000502:physiology*; D051381:Rats; D011950:Receptors, Cholinergic / Q000187:drug effects; D012584:Sciatic Nerve / Q000502:physiology
D011950:Receptors, Cholinergic; D000109:Acetylcholine