[Preferential affinity of acetylcholine receptor protein for certain lipids studied using monolayer cultures].
The interaction of the cholinergic (nicotinic) receptor protein purified from Torpedo marmorata electric organ with lipidic monomolecular films is studied at constant film area or constant superficial pressure. In both experimental situations, it is incorporated more efficiently into cholesterol than into egg lecithin films without showing any selectivity for a particular phospholipid class.
D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D002784:Cholesterol; D004557:Electric Organ / Q000378:metabolism; D005399:Fishes; D007700:Kinetics; D008024:Ligands; D010713:Phosphatidylcholines; D011950:Receptors, Cholinergic / Q000378:metabolism; D011978:Receptors, Nicotinic / Q000378:metabolism
D008024:Ligands; D010713:Phosphatidylcholines; D011950:Receptors, Cholinergic; D011978:Receptors, Nicotinic; D002784:Cholesterol; D000109:Acetylcholine
Affinité préférentielle de la protéine réceptrice de l'acétylcholine pour certains lipides révélée par la méthode des monocouches.