A double-blind comparison of meptazinol with pentazocine and placebo in cancer pain.
Two consecutive double-blind, crossover, single-administration trials have shown that intramuscular meptazinol, a new opioid-antagonist drug, is superior to placebo and equivalent ot pentazocine in relieving chronic pain due to cancer.
D000700:Analgesics / Q000627:therapeutic use*; D000818:Animals; D001381:Azepines / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D000882:Haplorhini; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D051379:Mice; D009369:Neoplasms / Q000188:drug therapy*; D010148:Intractable Pain / Q000188:drug therapy*; D010423:Pentazocine / Q000627:therapeutic use*; D051381:Rats
D000700:Analgesics; D001381:Azepines; D010423:Pentazocine