Transitory blindness during ethanol and phenethylbiguanide induced lactic acidosis in a subject with diabetes mellitus. A case report.
Transitory blindness is described in a diabetic patient with typical ethanol- and phenethylbiguanide induced lactic acidosis. The blindness developed in the course of 8 hours, but the vision returned during treatment with iv bicarbonate, insulin and glucose. The condition is discussed in relation to a presumed inhibition of the oxidative metabolism in the retina.
D000435:Alcoholic Intoxication / Q000150:complications*; D001766:Blindness / Q000139:chemically induced*; D016883:Diabetic Ketoacidosis / Q000097:blood / Q000139:chemically induced* / Q000150:complications; D003930:Diabetic Retinopathy / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007773:Lactates / Q000097:blood; D008875:Middle Aged; D010629:Phenformin / Q000009:adverse effects*
D007773:Lactates; D010629:Phenformin