Attenuation of the diuretic effect of dopamine by droperidol in man and dogs.
The effects of dopamine 0.5--6.0 microgram kg-1 min-1 on urine flow and the excretion of sodium and inorganic phosphate were studied in patients and dogs. In both the patients and the animals the diuretic effect of dopamine was augmented by the i.v. administration of droperidol 0.25 mg kg-1. Similarly, the excretion of sodium and inorganic phosphate was increased by droperidol.
D000328:Adult; D000818:Animals; D004231:Diuresis / Q000187:drug effects*; D004285:Dogs; D004298:Dopamine / Q000494:pharmacology*; D004329:Droperidol / Q000494:pharmacology*; D004357:Drug Synergism; D005260:Female; D006801:Humans; D008297:Male; D010710:Phosphates / Q000652:urine; D012964:Sodium / Q000652:urine; D013997:Time Factors
D010710:Phosphates; D012964:Sodium; D004329:Droperidol; D004298:Dopamine