[Long term in vivo and in vitro effect of sulfonylurea compounds on the islands of Langerhans of rat pancreas. Existence of a feedback mechanism between storage and synthesis apparatus of beta cells].
D000818:Animals; D005246:Feedback; D005947:Glucose / Q000494:pharmacology; D005905:Glyburide / Q000494:pharmacology*; D066298:In Vitro Techniques; D007328:Insulin / Q000096:biosynthesis*; D007329:Insulin Antagonists / Q000494:pharmacology; D007515:Islets of Langerhans / Q000187:drug effects* / Q000378:metabolism; D007930:Leucine / Q000378:metabolism; D011384:Proinsulin / Q000096:biosynthesis*; D051381:Rats; D014044:Tolbutamide / Q000494:pharmacology*
D007328:Insulin; D007329:Insulin Antagonists; D011384:Proinsulin; D014044:Tolbutamide; D007930:Leucine; D005947:Glucose; D005905:Glyburide
Langzeitwirkung von Sulfonylharnstoffen in vitro und in vivo auf die Langerhansschen Inseln des Rattenpankreas. Zur Frage der Existenz eines Rückkoppelungsmechanismus zwischen dem Speicher- und Syntheseapparat der Betazelle.