title: Lymphoid follicular pattern: a normal feature of the pediatric colon.
abstract: Tiny nodular filling defects up to 2 mm in diameter were seen in 12 of 27 patients under the age of 15 years undergoing double contrast enema. The pattern was particularly common in children under 5 years in whom a good quality double contrast study was obtained. While this pattern has been termed lymphoid hyperplasia, we believe it represents a normal lymphoid follicular pattern in the pediatric colon. The term lymphoid hyperplasia should be reserved for cases in which the lymphoid follicles are greater than 2 mm in diameter; this will usually represent an abnormal condition in response to infection, allergy, or immunologic disorders. The differential diagnosis of the lymphoid follicular pattern and lymphoid hyperplasia is briefly discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000361:Agammaglobulinemia / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D003106:Colon / Q000000981:diagnostic imaging* / Q000473:pathology; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics; D003424:Crohn Disease / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000000981:diagnostic imaging; D007223:Infant; D007417:Intestinal Polyps / Q000000981:diagnostic imaging / Q000235:genetics; D008221:Lymphoid Tissue / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D011859:Radiography