Is there a physiological intravascular coagulation in obstetrical cases?
The concentrations of plasmatic fibrinogen and its degradation products (FDPs), and the paracoagulation test using serial dilution of protamine sulphate (SDPS) were determined during the third trimester of pregnancy, labor, and puerperium. Singificant increases in the concentrations of fibrinogen and FDPs were observed throughout the process of pregnancy and birth, combined with both positive and negative SDPS tests. We suggest that these findings do not indicate a process of physiological DIC.
D001780:Blood Coagulation Tests; D004211:Disseminated Intravascular Coagulation; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D011247:Pregnancy; D013431:Sulfates
D005338:Fibrin Fibrinogen Degradation Products; D013431:Sulfates; D005340:Fibrinogen