[Effect of tranquilizers on cerebral cortex excitability in cats].
Chronic tests on cats showed that diazepam and nitrazepam lower the amplitude of primary responses (PR) of the second somatosensory zone of the brain cortex both to a single and paired stimulation of the thalamo-cortical radiation of fibers. Meprotan, while potentiating the PR to a single stimulation, does not influence the course of the PR restitution cycles. Benacryzine, while enhancing the PR to a single stimulation, produces the appearance of a lengthy phase of depression throughout the PR restitution cycle. In acute tests with unanesthetized, flaxedil immobilized cats, with an isolated cortical band underneath a stimulating electrode, analogous changes in PR both to a single and paired stimulation of the thalamo-cortical radiation of fibers were noted.
D000818:Animals; D001535:Benactyzine / Q000494:pharmacology*; D002415:Cats; D003975:Diazepam / Q000494:pharmacology*; D004558:Electric Stimulation; D004594:Electrophysiology; D005260:Female; D008297:Male; D008620:Meprobamate / Q000494:pharmacology*; D009434:Neural Pathways / Q000187:drug effects; D009567:Nitrazepam / Q000494:pharmacology*; D013003:Somatosensory Cortex / Q000187:drug effects*; D013787:Thalamic Nuclei / Q000187:drug effects
D001535:Benactyzine; D009567:Nitrazepam; D008620:Meprobamate; D003975:Diazepam
Vliianie trankvilizatorov na vozbudimost' kory golovnogo mozga koshek.