title: Synthesis of 1-phenyl-2-(phenylcarbamoyl)pyrazolidines as potential anticonvulsant agents.
abstract: Twelve 1-phenyl-2-(phenylcarbamoyl)pyrazolidines were synthesized from 1-arylpyrazolidines and aryl isocyanates. These adducts showed little anticonvulsant activity in the maximal electroshock seizure and pentylenetetrazol seizure assays.
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis*; D004597:Electroshock; D051379:Mice; D010433:Pentylenetetrazole / Q000037:antagonists & inhibitors; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000927:Anticonvulsants; D011720:Pyrazoles; D010433:Pentylenetetrazole