IgD myeloma: immunology and ultrastructure.
A case of multiple myeloma producing IgD-M component with light chains of lambda type is reported. It involved the skeleton and was complicated by compression of the spinal cord and massive extension to the pleura. The urine contained lambda Bence Jones protein. Under the electron microscope, the neoplastic plasma cells showed dissociation between nuclear and cytoplasmic maturation.
D000368:Aged; D001536:Bence Jones Protein / Q000652:urine; D006801:Humans; D007072:Immunoglobulin D / Q000378:metabolism*; D007146:Immunoglobulin lambda-Chains / Q000378:metabolism; D008297:Male; D009101:Multiple Myeloma / Q000145:classification / Q000276:immunology* / Q000648:ultrastructure; D009194:Myeloma Proteins / Q000378:metabolism*; D011947:Receptors, Antigen, B-Cell / Q000378:metabolism
D007072:Immunoglobulin D; D007146:Immunoglobulin lambda-Chains; D009194:Myeloma Proteins; D011947:Receptors, Antigen, B-Cell; D001536:Bence Jones Protein