[Phagocytic-activity in high risk patients of a surgical intensive care unit (author's transl)].
The in vitro phagocytic activity from PMNL against eight different Klebsiella strains, isolated from clinical material, was investigated and the K-index calculated for fifteen patients from a surgical intensive care unit. The hemagglutinating antibody titers against the test strains, as well as the serum concentrations of IgM, IgG, C3 and C4 were also determined. At the time of the investigation all patients had symptoms of a severe general infection. There could be no decrease in the phagocytic activity demonstrated. However, large variations against certain bacterial strains were observed. This same strain dependency was also observed for five healthy persons. The hemagglutinating antibody titers of any one patient were either generally increased for all strains or uniformly decreased. The serum concentrations of IgM, IgG, C3 and C4 were found to be, in general, within the normal large.
D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000032:analysis; D001424:Bacterial Infections / Q000276:immunology*; D002478:Cells, Cultured; D003165:Complement System Proteins / Q000032:analysis; D006098:Granulocytes / Q000276:immunology*; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007362:Intensive Care Units; D007709:Klebsiella / Q000276:immunology; D008875:Middle Aged; D010587:Phagocytosis; D011183:Postoperative Complications
D000907:Antibodies, Bacterial; D007136:Immunoglobulins; D003165:Complement System Proteins
Phagozytose-Aktivität bei gefährdeten Patienten einer chirurgischen Intensivstation.