Computer simulation of the effectiveness of male-linked translocations for the control of Anopheles albimanus Wiedemann.
A deterministic simulation model was used to establish the potential value of releasing male-linked translocation heterozygotes as a control measure for Anopheles albimanus Wiedemann. Theoretical population reductions exceeding 90% were obtained within 90 and 120 days after releases at initial ratios of 5 translocation males (TM): 1 normal male (NM) and 1 TM: 1 NM, respectively. Additional simulations emphasized the importance of the need for a method that would eliminate females from the release material. Releases containing 15% females were less effective than those with none. When a malaria subroutine was included in the model, the calculations showed that all the theoretical releases greatly reduced the number of malaria-infective females and therefore would have a profound effect on transmission of the disease. The number of malaria-infective females present was eliminated completely when only translocation males were released; however, a small number were present when the releases contained 15% females. Male-linked translocation males required longer periods of time to bring about population control than males that were completely sterile.
D000818:Animals; D000852:Anopheles / Q000235:genetics*; D003201:Computers; D005260:Female; D005298:Fertility; D006579:Heterozygote; D008288:Malaria / Q000517:prevention & control* / Q000635:transmission; D008297:Male; D008954:Models, Biological; D011156:Population Density; D014178:Translocation, Genetic