title: [Pharmacodynamics of anti-inflammatory preparations in body exposure to a physical therapeutic factor].
abstract: The analgetic and antipyretic action of acetylsalicylic acid is potentiated, whereas that of butadion and amidopyrine is decreased in the conditions of prior action of peloid skin applications (body temperature 42 degrees C). The effect of phenobarbital rises and that of butadion remains unchanged, whereas the inhibitory effect of ethazol revealed in the course of investigations of levelled under conditions of the action of the physical factor on the microsomal system. This leads to the changes in biotransformation and pharmacodynamics of the drugs.
mesh_terms: D000632:Aminopyrine / Q000008:administration & dosage; D000698:Analgesia / Q000379:methods; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001241:Aspirin / Q000008:administration & dosage; D001831:Body Temperature / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D005260:Female; D005334:Fever / Q000188:drug therapy; D008297:Male; D009094:Mud Therapy; D010634:Phenobarbital / Q000008:administration & dosage; D010653:Phenylbutazone / Q000008:administration & dosage; D026741:Physical Therapy Modalities; D011749:Pyrogens / Q000008:administration & dosage; D051381:Rats; D011919:Rats, Inbred Strains; D012007:Rectum; D013830:Thiadiazoles / Q000008:administration & dosage; D013997:Time Factors
chemical_list: D000893:Anti-Inflammatory Agents; D011749:Pyrogens; D013830:Thiadiazoles; D000632:Aminopyrine; D010653:Phenylbutazone; D001241:Aspirin; D010634:Phenobarbital
vernacular_title: Izuchenie farmakodinamiki protivovospalitel'nykh preparatov v usloviiakh vozdeĭstviia na organizm fizicheskogo lechebnogo faktoka.