[The influences of hyperbaric oxygen (OHP) on the normal inner ear of guinea pigs. Simultaneous registrations of cochlea microphonics (CM) and nerve potentials (AP) (author's transl)].
Guinea pigs were treated with 3 bar oxygen pressure in a hyperbaric chamber and CMs and APs were simultaneously registrated. The results depended on the kind of the usual anesthesy. If nembutal i.p. was used, the CMs and APs had been increased significant shortly after oxygen pressure reached 3 bar (CMs increased more than APs). If urethane i.p. was used, the CMs and APs increases not so significantly. These results are traced back to the different effect of the both anesthetic drugs on the blood flow in the brain. Oxygen toxicity in the inner ear was observed after OHP of 3 bar more than 30 min but only by APs. The CMs didn't show any signs of oxygen toxicity under the same conditions during 60 min and more.
D000161:Acoustic Stimulation; D000200:Action Potentials; D000777:Anesthetics; D003051:Cochlea / Q000502:physiology; D007758:Ear, Inner / Q000187:drug effects*; D006931:Hyperbaric Oxygenation; D010100:Oxygen / Q000494:pharmacology* / Q000633:toxicity; D014520:Urethane
D000777:Anesthetics; D014520:Urethane; D010100:Oxygen
Die Wirkung von hyperbarem Sauerstoff (OHP) auf das normale Innenohr des Meerschweinchens. Simultane Ableitungen von Cochleamikrophonpotentialen (CM) und Nervenaktionspotentialen (AP).