Effects of 17beta-estradiol on the replication of rubella virus in an estrogen-responsive, continuous cell line.
A 70% reduction in the number of infectious rubella virions normally produced in MCF-7 cells occurred when the cells were stimulated with 17beta-estradiol. Analysis of virus-induced RNA indicated a delay in the conversion of replicative intermediate to virion RNA.
D002460:Cell Line; D004958:Estradiol / Q000494:pharmacology*; D012367:RNA, Viral / Q000032:analysis / Q000096:biosynthesis; D012412:Rubella virus / Q000187:drug effects* / Q000254:growth & development
D012367:RNA, Viral; D004958:Estradiol