title: [Study of the electrophoretic and kinetic properties of erythrocyte glucose-6-phosphate dehydrogenase in hereditary enzyme deficiencies. Description of a new variant of glucose-6-phosphate dehydrogenase: the Gd Kremenchug].
abstract: A study of the activity of human erythrocyte G-6-PD has been completed on a great number of normal controls, coming from different regions of the USSR. This study has led to the discovery of a new variant of erythrocytic Gd, which was named "Kremenchug" from the origin of the patient. This new Gd, has a very low Km for G-6-P, and has a greater affinity for 2-deoxyglucose-6-phosphate. The maximal activity versus the pH of the medium is also characteristic of this new Gd.
mesh_terms: D000328:Adult; D002648:Child; D004586:Electrophoresis; D014644:Genetic Variation; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics*; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000235:genetics*; D006801:Humans; D007700:Kinetics; D008297:Male
chemical_list: D005954:Glucosephosphate Dehydrogenase
vernacular_title: Etude des propriétés électrophorétiques et cinétiques de la glucose-6-phosphate déshydrogénase (Gd) d'érythrocytes dans les déficits héréditaires de l'enzyme description d'une nouvelle variante de glucose-6-phosphate déshydrogénase: la Gd Kremenchug.