Proximal gastric vagotomy and suprapyloric antrectomy. Experimental evaluation in dogs.
In five dogs with Heidenhain pouches, proximal gastric vagotomy and suprapyloric antrectomy did not alter the rate of gastric emptying of 300 mL of 1% dextrose or of 40 plastic spheres, or disrupt the barricade preventing duodenogastric reflux. However, the operation did slow gastric emptying of 50 g of cubed liver and increase the postprandial secretion of hydrochloric acid from the pouch. We concluded that suprapyloric antrectomy can be combined with proximal gastric vagotomy without disturbing the gastric emptying of liquids and indigestible solids or resulting in increased duodenogastric reflux. However, the operation does slow gastric emptying of digestible solids.
D000818:Animals; D004285:Dogs; D004378:Duodenal Diseases / Q000517:prevention & control; D004594:Electrophysiology; D005260:Female; D005746:Gastric Emptying; D005750:Gastric Juice / Q000378:metabolism; D005764:Gastroesophageal Reflux / Q000517:prevention & control; D008722:Methods; D011706:Pyloric Antrum / Q000601:surgery*; D013270:Stomach / Q000294:innervation* / Q000601:surgery; D014628:Vagotomy / Q000379:methods