Use of nitrogen-specific detector for GLC determination of plasma bucainide.
A sensitive and specific GLC determination of plasma bucainide was developed using a nitrogen-specific detector. The method permits the determination of bucainide as low as 5.0 ng/ml of plasma and provides sufficient sensitivity and reproducibility for clinical use.
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000097:blood*; D002849:Chromatography, Gas / Q000295:instrumentation; D004285:Dogs; D006801:Humans; D008722:Methods; D009584:Nitrogen / Q000032:analysis; D010879:Piperazines / Q000097:blood*
D000889:Anti-Arrhythmia Agents; D010879:Piperazines; C019280:bucainide; D009584:Nitrogen