Delayed type hypersensitivity to bovine serum albumin and to lipid-conjugated bovine serum albumin in mice.
Delayed type hypersensitivity (DTH) to bovine serum albumin (BSA) and to lipid-conjugated BSA were studied comparatively. Unlike the case of BSA with which no DTH can be detected with native antigen, injection of butyric-conjugated BSA (Bu-BSA) in sensitized mice provokes a typical DTH for an early and limited period. Alum-precipitated Bu-BSA (Al-Bu-BSA) provokes from the beginning a stronger DTH which persists a much longer period.
D000534:Alum Compounds / Q000494:pharmacology; D000818:Animals; D002087:Butyrates / Q000494:pharmacology; D002417:Cattle; D005260:Female; D005620:Freund's Adjuvant / Q000494:pharmacology; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D008055:Lipids / Q000494:pharmacology*; D051379:Mice; D012710:Serum Albumin, Bovine / Q000276:immunology*
D000534:Alum Compounds; D002087:Butyrates; D008055:Lipids; D012710:Serum Albumin, Bovine; D005620:Freund's Adjuvant