Development of glomerular fibrinolytic activity in the rat.
Fibrinolytic activity of the glomeruli was studied in rats of different age using the fibrin-slide technic. In normal rats glomerular fibrinolytic activity (GFA) was relatively low. After a single injection of liquoid (sodium polyanethol sulfonate), a pronounced increase of GFA was evident. The superficial nephrons had a significantly higher GFA than the juxtamedullary nephrons. Compared with rats 2 months of age, rats 2 weeks of age showed a greater GFA in all the glomeruli.
D000375:Aging; D000818:Animals; D001780:Blood Coagulation Tests; D004211:Disseminated Intravascular Coagulation / Q000503:physiopathology; D005342:Fibrinolysis; D007678:Kidney Glomerulus / Q000503:physiopathology*; D008297:Male; D011108:Polymers / Q000008:administration & dosage; D051381:Rats
D011108:Polymers