Collagen breakdown and ammonia inhalation.
Measurement of several urinary metabolites of hydroxylysine indicates that considerable collagen degradation occurred in four individuals immediately after they had inhaled concentrated ammonia vapors. Since clinical and/or radiological evidence of intense upper respiratory and pulmonary inflammation were evident, it is likely that collagen degradation occurred at the level of the respiratory system.
D000293:Adolescent; D000641:Ammonia / Q000506:poisoning*; D002648:Child; D003094:Collagen / Q000378:metabolism*; D003404:Creatinine / Q000652:urine; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D006901:Hydroxylysine / Q000378:metabolism / Q000652:urine*; D007223:Infant; D008297:Male; D012140:Respiratory Tract Diseases / Q000139:chemically induced
D006901:Hydroxylysine; D000641:Ammonia; D003094:Collagen; D003404:Creatinine