Outcome of Listeria monocytogenes infection in compromised and non-compromised adults; a comparative study of seventy-two cases.
The mortality in listeric meningitis and septicaemia, the two main clinical manifestations of the infection, is generally considered to be high. However, co-existing disorders rather than the listeric infection itself seem to determine the outcome. In the present study of 72 listeric infections among non-pregnant adults, 28 patients without co-existing disease had a fatality rate of 10.7% as compared to 57.9% among 19 immunocompromised individuals. Finally, in a third group of listeric patients, including alcoholics and people with heart disease or diabetes mellitus, the fatality rate was 24.0%.
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008088:Listeriosis / Q000150:complications / Q000188:drug therapy / Q000401:mortality*; D008584:Meningitis, Listeria / Q000401:mortality; D008875:Middle Aged; D018805:Sepsis / Q000401:mortality
D000900:Anti-Bacterial Agents