Heart disease risk factors and hormone use in postmenopausal women.
A population of 1,496 women aged 55 to 74 years was studied for the distribution of heart disease risk factors in the presence or absence of postmenopausal estrogens. Current hormone use was reported by 39%. Hormone users were significantly slimmer than nonusers at all ages. After adjustment for the effect of obesity, hormone users had significantly lower mean levels of plasma cholesterol and higher mean levels of plasma triglycerides than nonusers. Blood pressure and fasting plasma glucose concentration tended to be lower among hormone users, although the differences were not statistically significant in all age groups. This article discusses the theoretical implications of these observations for cardiovascular disease mortality and contrasts them with the cancer risk of postmenopausal estrogen use.
D000367:Age Factors; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D002140:California; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000175:diagnosis / Q000453:epidemiology*; D003920:Diabetes Mellitus / Q000235:genetics; D004967:Estrogens / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D009203:Myocardial Infarction / Q000235:genetics; D009765:Obesity; D012306:Risk; D012907:Smoking; D012923:Social Class; D014280:Triglycerides / Q000097:blood
D001786:Blood Glucose; D004967:Estrogens; D014280:Triglycerides; D002784:Cholesterol