Asplenia syndrome. Report of two cases.
Two babies with asplenia syndrome are described. Both presented with the severe cardiovascular anomalies found in this syndrome and had Howell-Jolly bodies in peripheral blood smears. The chest X-rays showed dextrocardia, decreased pulmonary circulation and a horizontal symmetrical liver, and were helpful in the clinical diagnosis. Additional findings at autopsy included a mobile cecum and bilateral trilobed lungs with bilateral eparterial bronchi.
D000015:Abnormalities, Multiple; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013154:Spleen / Q000002:abnormalities*; D013577:Syndrome