Detection of complement (c3d) coated cells in a newborn due to maternal anti-i.
A case of a positive direct antiglobulin test on a newborn's cord red blood cells caused by maternal anti-i is reported. The direct antiglobulin test was moderately positive using polyspecific antiglobulin reagent and monospecific anti-C3d, but negative using monospecific anti-IgG. The infant showed no clinical signs of hemolytic disease of the newborn.
D001789:Blood Group Antigens; D003176:Complement C3 / Q000032:analysis; D003298:Coombs Test; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D005312:Fetal Blood; D006801:Humans; D007048:I Blood-Group System; D007074:Immunoglobulin G / Q000032:analysis; D007231:Infant, Newborn; D007518:Isoantibodies / Q000032:analysis*; D008297:Male; D011247:Pregnancy
D001789:Blood Group Antigens; D003176:Complement C3; D007048:I Blood-Group System; D007074:Immunoglobulin G; D007518:Isoantibodies