Effects of D-alpha-aminoadipate on physiologically evoked responses of cat dorsal horn neurones.
Microelectrophoretic administration of D-alpha-aminoadipate reversibly reduced excitatory responses of cat dorsal horn neurones evoked by iontophoretic glutamate and non-noxious peripheral stimuli but did not influence similar responses evoked by noxious peripheral stimuli or iontophoretic substance P.
D015074:2-Aminoadipic Acid / Q000494:pharmacology*; D000600:Amino Acids, Dicarboxylic / Q000494:pharmacology*; D000818:Animals; D002415:Cats; D005971:Glutamates / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D013116:Spinal Cord / Q000166:cytology* / Q000502:physiology; D013569:Synapses / Q000187:drug effects / Q000502:physiology*
D000600:Amino Acids, Dicarboxylic; D005971:Glutamates; D015074:2-Aminoadipic Acid