Fatty-acid synthesis in lactating-goat mammary gland. 1. Medium-chain fatty-acid synthesis.
Tissue slices from lactating goat-mammary gland synthesized short (C4:0 and C6:0), medium (C8:0 and C10:0) and long-chain (C12:0 to C16:0) fatty acids in proportions similar to that found in goat milk fat. In contrast, the particle-free supernatant fraction and the purified fatty acid synthetase from this tissue synthesized predominantly short-chain and long-chain fatty acids. Terminating acyl-thioesterases of low molecular weight could not be detected in the particle-free supernatant. Addition of the microsomal fraction to the particle-free supernatant induced the synthesis of medium-chain fatty acids in proportions which were similar to those found in goat milk fat.
D000105:Acetyl Coenzyme A / Q000378:metabolism; D000818:Animals; D003600:Cytosol / Q000502:physiology; D064429:Fatty Acid Synthases / Q000378:metabolism; D005227:Fatty Acids / Q000096:biosynthesis*; D005260:Female; D006041:Goats; D007774:Lactation; D008321:Mammary Glands, Animal / Q000378:metabolism*; D011247:Pregnancy; D011817:Rabbits
D005227:Fatty Acids; D000105:Acetyl Coenzyme A; D064429:Fatty Acid Synthases