Carbon dioxide sensitivity of aortic chemoreceptors in the cat.
Steady state CO2 sensitivity in the aortic chemoreceptors was variable. For 70.3% of the steady state response lines to increasing CO2 the slope was not significantly different from zero. For 24.3%, it was significantly positive and for 5.4% significantly negative. In contrast, in 86.7% of cases the oscillating response to alternate breaths of high and low CO2 suggested a transient response line which was significantly steeper than the steady state line. Removing CO2 from a high CO2 content inspirate for one breath caused a distinct drop in discharge on 83.3% of occasions. The significance of such transient CO2 sensitivity in the absence of clear steady state sensitivity is discussed.
D000818:Animals; D001011:Aorta / Q000294:innervation*; D001794:Blood Pressure; D002245:Carbon Dioxide; D002415:Cats; D002628:Chemoreceptor Cells / Q000502:physiology*; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000502:physiology; D008297:Male; D012119:Respiration
D002245:Carbon Dioxide