title: [Immune serum globulin E in patients with leukoplakia (author's transl)].
abstract: Significant changes of humoral factors can occur during the development and growth of malignant tumors. Such can be observed by the periodic recording of immune serum globulin E levels if sensitive RIA methods are employed. Observations of normal persons show largely stable immune serum globulin E levels, and are comparable in patients with leukoplakia of the larynx as well as in patients whose malignant conditions were removed by oepration or radiotherapy. In three patients, a statistically significant increase in serum immune globulin E was recorded immediately before malignant degeneration of known leukoplakia occurred, and was also found in 22 control tumor patients who had experienced local relapses of disease.
mesh_terms: D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D007457:Iodine Radioisotopes; D007822:Laryngeal Neoplasms / Q000276:immunology*; D007971:Leukoplakia / Q000276:immunology*; D011863:Radioimmunoassay; D012008:Recurrence
chemical_list: D007457:Iodine Radioisotopes; D007073:Immunoglobulin E
vernacular_title: Serum-Immunoglobulin-E bei Leukoplakiepatienten.