Autotransfusion following cardiac operations: a randomized, prospective study.
To evaluate the safety and effectiveness of the collection and retransfusion of postoperatively shed mediastinal blood as part of a multifaceted approach to blood conservation following cardiac operation, 113 patients were randomized into either an autotransfusion group (54 patients) or a control group (59 patients). Intraoperative and postoperative hemodilution was practiced in all patients. The clinical safety of this technique was confirmed by the lack of septic, hematological, pulmonary, renal, or hepatic complications. However, in this setting where blood conservation is already aggressively practiced, the ability of the technique to further reduce the use of banked blood following cardiac surgical procedures was not demonstrated.
D000328:Adult; D000368:Aged; D001780:Blood Coagulation Tests; D001800:Blood Specimen Collection; D001804:Blood Transfusion, Autologous / Q000009:adverse effects / Q000379:methods*; D006348:Cardiac Surgical Procedures; D003365:Costs and Cost Analysis; D004209:Disposable Equipment; D005260:Female; D006801:Humans; D008297:Male; D008482:Mediastinum; D008722:Methods; D008875:Middle Aged; D009204:Myocardial Revascularization; D011182:Postoperative Care; D011183:Postoperative Complications; D011446:Prospective Studies