[Plasma ion changes in venous blood incubated with beta receptor blockers and subjected to tonometry in vitro. 1. Study using propranolol].
The Authors considered the variations in electrolyte plasmatic assessment in blood samples incubated "in vitro" with propranolol (48 gamma/10 cc) and part of sample incubated with propranolol and theophyllin-ethilandiamin. The evaluation of electrolyte assessment was performed at 20'-40'-60' after tonometration. Sodium and potassium values increase in the samples with the beta-blocking agent and are statistically significant only after 20'; in further controls the increasing values persist. Chloride rises too, marked by a low statistic significance. No variations were observed in samples incubated also with propranolol and antiphosphodiestherasic agent. The Authors suggest trat data should confirm ionic transport blockage across the red cell membrane obtained with theophylline.
D001692:Biological Transport / Q000187:drug effects; D002712:Chlorides / Q000097:blood; D004910:Erythrocyte Membrane; D005029:Ethylenediamines / Q000494:pharmacology; D006801:Humans; D010726:Phosphodiesterase Inhibitors / Q000494:pharmacology; D011188:Potassium / Q000097:blood; D011433:Propranolol / Q000494:pharmacology*; D012964:Sodium / Q000097:blood; D013806:Theophylline / Q000494:pharmacology; D014065:Tonometry, Ocular
D002712:Chlorides; D005029:Ethylenediamines; D010726:Phosphodiesterase Inhibitors; D012964:Sodium; D011433:Propranolol; D013806:Theophylline; D011188:Potassium
Le modificazioni joniche del plasma di sangue venoso incubato e tonometrato "in vitro" con farmaci attivi sui beta-recettori.