title: Hydroxylase cofactor activity in cerebrospinal fluid of normal subjects and patients with Parkinson's disease.
abstract: A method for measuring hydroxylase cofactor activity in human cerebrospinal fluid is described. The hydroxylase cofactor content of cerebrsopinal fluid from Parkinsonian patients is approximately 50 percent that of normal subjects. A significant correlation between hydroxylase cofactor and the concentration of homovanillic acid in the cerebrospinal fluid was observed.
mesh_terms: D001708:Biopterins / Q000031:analogs & derivatives / Q000032:analysis / Q000134:cerebrospinal fluid*; D006719:Homovanillic Acid / Q000134:cerebrospinal fluid; D006801:Humans; D008722:Methods; D010300:Parkinson Disease / Q000134:cerebrospinal fluid*; D011621:Pteridines / Q000134:cerebrospinal fluid*
chemical_list: D011621:Pteridines; D001708:Biopterins; D006719:Homovanillic Acid