Immune disturbances after severe enteritis during the first six months of life.
Infants with severe enteritis and associated prolonged thymic atrophy during the first six months of life showed persistent cell-mediated immune deficiency between the ages of three and five years. Experimental investigations show that early intrauterine and extrauterine stress may lead to permanent cell-mediated immune deficiency and an imbalanced immune response. Trends in disease frequency among different population groups may be influenced in part by the immunity of the host.
D000818:Animals; D002648:Child; D002675:Child, Preschool; D004137:Dinitrochlorobenzene / Q000276:immunology; D004751:Enteritis / Q000000981:diagnostic imaging / Q000276:immunology*; D006168:Guinea Pigs; D006801:Humans; D007111:Immunity, Cellular; D007114:Immunization; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis; D007223:Infant; D011859:Radiography; D012882:Skin Tests; D013950:Thymus Gland / Q000000981:diagnostic imaging
D004137:Dinitrochlorobenzene; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins