title: The complement fixation test and African trypanosomiasis: I. Experimental infection and re-infection in cattle before and after treatment.
abstract: The complement fixation test was applied to assess antibody responses in cattle infected with T. brucei, T. congolense, and T. vivax which had been treated and re-infected. After the first infection, the specificity of the results was low in T. congolense, fair in T. brucei, and high in T. vivax infected animals. After re-infection with the same trypanosoma species as used for previous infections, the specificity of CF results was high in all cases. After a foregoing T. vivax infection, specific titres of T. congolense and to a lesser degree of T. brucei infections were frequently masked by residual T. vivax titres. After treatment of trypanosoma-infected cattle the fasted drop of CF antibody titres occurred in T. congolense cases, followed by T. brucei infections. T. vivax titres persisted over prolonged periods.
mesh_terms: D000818:Animals; D000906:Antibodies / Q000032:analysis; D000918:Antibody Specificity; D002417:Cattle; D003168:Complement Fixation Tests; D004133:Diminazene / Q000627:therapeutic use; D008297:Male; D012008:Recurrence; D013997:Time Factors; D014344:Trypanocidal Agents / Q000627:therapeutic use; D014353:Trypanosomiasis, African / Q000662:veterinary*; D014354:Trypanosomiasis, Bovine / Q000188:drug therapy / Q000276:immunology*
chemical_list: D000906:Antibodies; D014344:Trypanocidal Agents; D004133:Diminazene