Formation of benzo[a]pyrene metabolite-nucleoside adducts in isolated perfused rat and mouse liver and in mouse lung slices.
D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism*; D002273:Carcinogens; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis; D004247:DNA / Q000378:metabolism; D003853:Deoxyribonucleosides / Q000378:metabolism*; D004790:Enzyme Induction / Q000187:drug effects; D004852:Epoxy Compounds / Q000378:metabolism; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism*; D008168:Lung / Q000378:metabolism*; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D051379:Mice; D010477:Perfusion; D010634:Phenobarbital / Q000494:pharmacology; D012313:RNA / Q000378:metabolism; D051381:Rats; D012263:Ribonucleosides / Q000378:metabolism*
D001580:Benzopyrenes; D002273:Carcinogens; D003853:Deoxyribonucleosides; D004852:Epoxy Compounds; D012263:Ribonucleosides; D008748:Methylcholanthrene; D012313:RNA; D004247:DNA; D003577:Cytochrome P-450 Enzyme System; D010634:Phenobarbital