Early detection of inherited muscular dystrophy in chickens.
New Hampshire chickens, homozygous for inherited muscular dystrophy, display clinical manifestations at an early age. A fine structural examination of embryos from this strain shows marked degenerative changes four days prior to hatching. The Z bands appear to dissolve progressively to the point where finally the myofibrils become uniformly dense with no detectable banding patterns.
D000818:Animals; D002642:Chick Embryo; D003937:Diagnosis, Differential; D009132:Muscles / Q000196:embryology / Q000648:ultrastructure; D009137:Muscular Dystrophy, Animal / Q000175:diagnosis* / Q000235:genetics; D009210:Myofibrils / Q000648:ultrastructure