title: DNA of free and complexed origin in human plasma: concentration and length distribution.
abstract: The DNA content in plasma of five healthy human individuals has been estimated. Structures ascertained by electron microscopy have been identified as double-stranded DNA. Depending on the isolation procedure applied the DNA molecules found may originate from free and/or complexed forms of DNA. The lengths range from less than 0.2 microns up to about 13 microns. DNA concentration is in the range of 3 to 11 ng/ml.
mesh_terms: D002499:Centrifugation, Density Gradient; D004247:DNA / Q000097:blood* / Q000302:isolation & purification; D004277:DNA, Single-Stranded / Q000097:blood; D005260:Female; D005609:Free Radicals; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008970:Molecular Weight; D011485:Protein Binding
chemical_list: D004277:DNA, Single-Stranded; D005609:Free Radicals; D004247:DNA