title: Erythema chronicum migrans with purpura and polymorphonuclear infiltrates.
abstract: Erythema chronicum migrans with an intensely purpuric border developed in a 70-year-old woman. A biopsy specimen, in addition to showing the usual perivascular mononuclear infiltrate, demonstrated numerous polymorphonuclear leukocytes associated with leukocytoclasis. Immunofluorescence study showed vascular deposition of IgM and C3.
mesh_terms: D000368:Aged; D001733:Bites and Stings; D003176:Complement C3 / Q000032:analysis; D004890:Erythema / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D009504:Neutrophils / Q000473:pathology; D011693:Purpura / Q000209:etiology; D013987:Ticks
chemical_list: D003176:Complement C3; D007075:Immunoglobulin M