Yellow nail syndrome. Possible association with malignancy.
A dramatic resolution of yellow nail deformity occurred in a 66-year-old man shortly after the removal of a carcinoma of the larynx. Seventeen months later, a productive cough developed and radiologic evidence of bronchiectasis was found. There was no evidence of lymphedema, pleural effusion, sinusitis, or immunologic abnormalities. At least three other patients with a variant of yellow nail syndrome have died of malignancy. Therefore, the resolution of the nail deformity following laryngectomy may not be fortuitous.
D000368:Aged; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009260:Nail Diseases / Q000150:complications* / Q000628:therapy; D013577:Syndrome