Hepatotoxicity in disulfiram-treated patients.
Thirty-five alcoholics receiving disulfiram for 3 weeks showed no dose-related hepatotoxicity compared with controls, but 9 did exhibit non-dose-related subclinical hepatotoxicity.
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000437:Alcoholism / Q000188:drug therapy; D000469:Alkaline Phosphatase / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology / Q000209:etiology*; D004221:Disulfiram / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male
D007770:L-Lactate Dehydrogenase; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D004221:Disulfiram