title: Carcinoma arising in eccrine spiradenoma.
abstract: Two patients had carcinoma arising in eccrine spiradenoma. In both patients, recent changes in a long-standing cutaneous nodule prompted excision, and microscopic examination disclosed carcinoma intimately associated with and apparently arising from typical benign eccrine spiradenoma. One patient had lymph node metastasis.
mesh_terms: D000236:Adenoma / Q000473:pathology*; D000328:Adult; D000368:Aged; D004439:Eccrine Glands; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D013544:Sweat Gland Neoplasms / Q000473:pathology*; D013545:Sweat Glands