title: The production of chaetoglobosins, sterigmatocystin, O-methylsterigmatocystin, and chaetocin by Chaetomium spp. and related fungi.
abstract: Production of mycotoxins by Chaetomium spp. and related fungi on rice culture was examined by a combination of cytotoxicity tests using HeLa cells and thin-layer chromatography. Three species, C. mollipilium, C. rectum, and C. subaffine, as well as C. cochliodes and C. globosum, were proved to produce chaetoglobosins. From cultures of four strains of Chaetomium sp., assigned to C. thielavioideum, and one strain of Farrowia sp., chaetocin, sterigmatocystin, and O-methylsterigmatocystin were isolated. Morphological characteristics of the producers of sterigmatocystins are described.
mesh_terms: D001203:Ascomycota / Q000378:metabolism*; D002597:Chaetomium / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D003470:Culture Media; D006367:HeLa Cells / Q000187:drug effects; D006801:Humans; D026121:Indole Alkaloids; D007211:Indoles / Q000096:biosynthesis; D009183:Mycotoxins / Q000096:biosynthesis* / Q000633:toxicity; D012275:Oryza / Q000382:microbiology; D010879:Piperazines / Q000096:biosynthesis; D013045:Species Specificity; D013241:Sterigmatocystin / Q000031:analogs & derivatives / Q000096:biosynthesis
chemical_list: D003470:Culture Media; D026121:Indole Alkaloids; D007211:Indoles; D009183:Mycotoxins; D010879:Piperazines; D013241:Sterigmatocystin; C019290:chaetoglobosins