Immunoglobulin content of experimentally induced amyloid in hamsters.
Experimental amyloidosis in hamsters induced by Di-Te-Per vaccine was studied for periods of 14 to 126 days. Immunohistochemical analysis showed that after the 4th week of immunization amyloid deposits containing immunoglobulins accumulated in the liver, spleen and renal glomeruli. The amount of immunoglobulin in the amyloid deposits increased in the final stage in the kidneys, spleen and portal spaces of liver. In the spaces of Disse the amount of immunoglobulin after 4 and 18 weeks of immunization was similar.
D000686:Amyloidosis / Q000209:etiology / Q000276:immunology*; D000818:Animals; D001428:Bacterial Vaccines; D006224:Cricetinae; D004195:Disease Models, Animal; D007114:Immunization; D007136:Immunoglobulins / Q000032:analysis*; D007678:Kidney Glomerulus / Q000276:immunology; D008099:Liver / Q000276:immunology; D013154:Spleen / Q000276:immunology
D001428:Bacterial Vaccines; D007136:Immunoglobulins