Placental type of membrane-bound arylamidase (Shiba isoenzyme) found in human cancerous lung.
A placental type of membrane-bound arylamidase (Shiba isoenzyme) was found in the tissue of adenocarcinoma of the lung. Cancerous lung membrane-bound arylamidase had the same electrophoretic mobility, isoelectric point (pH 4.2), and susceptibility to SDS inactivation as placental membrane-bound arylamidase. Cancerous lung membrane-bound arylamidase had molecular weight and kinetic properties similar to normal lung membrane-bound arylamidase, but differed from the normal lung membrane-bound arylamidase with respect to electrophoretic mobility, isoelectric point, heat stability and inactivation by SDS.
D000626:Aminopeptidases / Q000378:metabolism*; D002462:Cell Membrane / Q000201:enzymology; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism; D007700:Kinetics; D008175:Lung Neoplasms / Q000201:enzymology*; D008970:Molecular Weight; D010920:Placenta / Q000201:enzymology
D007527:Isoenzymes; D000626:Aminopeptidases