[Nature of vagotomy and atropine hypercoagulation].
Bilateral vagotomy and i. v. administration of atropin entailed shortening of total and thrombin time and lowering of fybrinolysis. The vagotomy brought about the changes within 3--15 min, whereas the atropinization evoked them in about 30--60 min. The maximum shortening of total and thrombin time and lowering of fibrinolysis occurred at the moment of highest activity of the cervical sympathetic system. Thereupon these effects in the blood coagulating system seem to be called forth by activity of the sympathetic system after vagotomy.
D000818:Animals; D001285:Atropine / Q000494:pharmacology*; D001777:Blood Coagulation / Q000187:drug effects; D004594:Electrophysiology; D005260:Female; D005342:Fibrinolysis; D008297:Male; D011817:Rabbits; D051381:Rats; D011930:Reaction Time / Q000502:physiology; D013564:Sympathetic Nervous System / Q000502:physiology; D014628:Vagotomy; D014630:Vagus Nerve / Q000502:physiology*
D001285:Atropine
Priroda vagotomicheskoĭ i atropinovoĭ giperkoaguliatsii.