[Effect of craniocerebral hypothermic perfusion on the metabolism of ischemic brain].
Intravascular perfusion of the brain by colloid-saline "extracellular" fluid was carried out in 58 experimental dogs against the background of acute hypoxia. Biochemical indices of metabolism in flowing and outflowing brain fluid as well as in the brain tissue were studied. It was shown that under conditions of acute hypoxia normo- and particularly hypothermic intravascular perfusion of the brain by colloid-saline fluid decreases the disturbances of metabolic homeostasis.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002545:Brain Ischemia / Q000378:metabolism*; D002245:Carbon Dioxide / Q000378:metabolism; D004285:Dogs; D007036:Hypothermia, Induced; D007773:Lactates / Q000378:metabolism; D010084:Oxidation-Reduction; D010101:Oxygen Consumption; D011188:Potassium / Q000378:metabolism; D011773:Pyruvates / Q000378:metabolism; D012964:Sodium / Q000378:metabolism
D007773:Lactates; D011773:Pyruvates; D002245:Carbon Dioxide; D012964:Sodium; D011188:Potassium
Vliianie kraniotserebral'noĭ gipotermicheskoi perfuzii na metabolizm ishemizirovannogo mozga.