title: [Intensity of DNA synthesis in animal organs after a flight on the Kosmos-782 biosatellite].
abstract: With respect to H3-thymidine incorporation the rate of DNA synthesis in the liver, spleen and thymus of rats was determined in flight and synchronous rats. Six hours post-flight the rate of H3-thymidine incorporation into the liver of flight rats did not differ from the normal (vivarium controls) and was 50% higher than in the synchronous rats. In the spleen and thymus of flight animals this parameter was 60 and 33% below the norm. Similar but less pronounced changes in the spleen were found in the synchronous rats. Twenty-five days postflight the rate of DNA synthesis in lymph organs recovered completely and tended to increase, whereas in the liver it remained significantly below the norm.
mesh_terms: D000818:Animals; D004247:DNA / Q000096:biosynthesis*; D008099:Liver / Q000378:metabolism; D051381:Rats; D013026:Space Flight; D013154:Spleen / Q000378:metabolism; D013936:Thymidine / Q000378:metabolism; D013950:Thymus Gland / Q000378:metabolism; D013997:Time Factors; D014586:USSR
chemical_list: D004247:DNA; D013936:Thymidine
vernacular_title: Intensivnost' sintez DNK v organakh zhivotnykh posle poleta na biosputnike "Kosmos-782".