title: Isolation and characterization of a cycloheximide-resistant mutant of Acanthamoeba castellanii Neff.
abstract: A cycloheximide-resistant mutant was isolated from the amoeba Acanthamoeba castellanii Neff. Drug resistance was found to be due to a ribosomal modification.
mesh_terms: D000656:Amoeba / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D000818:Animals; D003513:Cycloheximide / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D005796:Genes; D009154:Mutation; D014176:Protein Biosynthesis; D012270:Ribosomes
chemical_list: D003513:Cycloheximide