title: [Combined chemotherapy of metastasing melanoblastoma using ifosfamide and cis-platinum (II)-diamminodichloride (author's transl)].
abstract: 15 patients with metastasing melanoblastoma of stage III and IV were treated with a combination of cis-platinum (II)-diamminodichloride and ifosfamide. In 3 cases complete remission occurred, in 5 partial remission with tumour regression of more than 50%. The response rate is around 50% at present. Two cases showed no change after 6 months of chemotherapy.
mesh_terms: D000328:Adult; D000368:Aged; D002945:Cisplatin / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000627:therapeutic use*; D008297:Male; D008545:Melanoma / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D009362:Neoplasm Metastasis
chemical_list: D003520:Cyclophosphamide; D002945:Cisplatin; D007069:Ifosfamide
vernacular_title: Kombinierte Chemotherapie des metastasierenden Melanoblastoms mit Ifosfamid und cis-Diamino-dichloro-platin (II).