Chromosome deletion [46,XX,del(20)(q11)] in agnogenic myeloid metaplasia.
A woman in the fourth year of agnogenic myeloid metaplasia was found to have partial deletion of the long arm of chromosome 20 [46,XX,del(20)(q11)] in mitoses of presumably immature myeloid cells from unstimulated cultures of peripheral blood and bone marrow. Cytogenetic studies of peripheral blood lymphocytes showed a normal female karyotype.
D001803:Blood Transfusion; D001853:Bone Marrow / Q000648:ultrastructure; D002872:Chromosome Deletion; D002903:Chromosomes, Human, 19-20; D005260:Female; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000648:ultrastructure; D008875:Middle Aged; D011087:Polycythemia Vera / Q000235:genetics; D055728:Primary Myelofibrosis / Q000235:genetics* / Q000628:therapy; D013156:Splenectomy