Optic neuropathy in ketogenic diet.
A symmetrical, bilateral optic neuropathy is reported in 2 patients being treated with ketogenic diets for seizure control. Laboratory tests suggested a thiamine deficiency, and both patients recovered normal visual function after several weeks of treatment with thiamine. The risk of optic nerve dysfunction occurring during the treatment with a ketogenic diet can be minimised if routine vitamin B supplements are given and periodic evaluation of optic nerve function undertaken.
D002648:Child; D002675:Child, Preschool; D004041:Dietary Fats / Q000009:adverse effects* / Q000627:therapeutic use; D004827:Epilepsy / Q000178:diet therapy*; D005260:Female; D006801:Humans; D008297:Male; D009901:Optic Nerve Diseases / Q000209:etiology*; D013832:Thiamine Deficiency / Q000209:etiology
D004041:Dietary Fats