[Effect of Mycoplasma arthritidis on mouse and rat lymphoid cells in experimental Mycoplasma infection].
Early stages of mycoplasma infection of mice and rats were accompanied by suppression of the populations of rosette- and plaque-forming cells. Later the character and dynamics of the immune response to M. arthritidis differed in mice and rats. In mice mycoplasma infection was accompanied by stimulation of rosette-forming cells with some suppression of the plaque-forming cells from the 7th to the 36th day of infection. In rats by the 7th day the number of plaque- and rosette-forming cells decreased in comparison with control, and the immune response was restored by the 15h day; at later periods the immune response of the infected rats exceeded the normal level considerably. The cellular and humoral immune reactions proved to depend on the mycoplasma dose.
D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D001170:Arthritis, Infectious / Q000276:immunology; D003114:Colony-Forming Units Assay; D007109:Immunity; D007111:Immunity, Cellular; D007114:Immunization; D008214:Lymphocytes / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009174:Mycoplasma / Q000276:immunology*; D009175:Mycoplasma Infections / Q000276:immunology*; D051381:Rats; D012397:Rosette Formation; D013997:Time Factors
D000907:Antibodies, Bacterial
Vliianie Mycoplasma arthritidis na limfoidnye kletki mysheĭ i krys pri éksperimental'noĭ mikoplazma-infektsii.