[The evidence of the chloramphenicol-sensibilisation by the usual lymphocyte transformation test (author's transl)].
As to its allergising capability Chloramphenicol holds a leading position. That's why the evidence of an existing sensibilisation is important. But there is a controversy concerning the usual lymphocyte transformation test (LTT). With the help of comparing tests (patch-test - LTT) a high rate of equal results between both the methods is shown. Thus, the efficiency of LTT basing on morphological analysing criteria, which is used for the evidence of an existing Chloramphenicol-sensibilisation seems to be proved.
D002701:Chloramphenicol / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology; D004342:Drug Hypersensitivity; D006801:Humans; D008213:Lymphocyte Activation; D009824:Ointments; D010328:Patch Tests; D012867:Skin / Q000473:pathology
D009824:Ointments; D002701:Chloramphenicol
Zum Nachweis der Chloramphenicol-Sensibilisierung mit Hilfe des auf morphologischen Auswertungskriterien basierenden Lymphozyten-Transformations-Tests.