[Possible indications for recently developed antibiotics [author's transl)].
Properties and possible indications of recently developed antibiotics are described. For the treatment of pseudomonas aeruginosa infections of all penicillins azlocillin is the most favourable drug (instead of carbenicillin), for treatment of esch. coli infections it is mezlocillin (instead of ampicillin). Becampicillin and equally amoxycillin are more than ampicillin suitable for oral application (because of almost complete absorption). Cefaclor has a broader spectrum and stronger activity than cefalexin and will replace cefalexin in future. Sisomicin is similar to gentamicin and has no essential advantages. Netilmicin seems to be less oto-and nephrotoxic than gentamicin and may be used with less risk of side-effects in patients with renal insufficiency. Amikacin is reserved for infections by gentamicin-resistant bacteria.
D000583:Amikacin / Q000627:therapeutic use; D000667:Ampicillin / Q000378:metabolism / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002511:Cephalosporins / Q000378:metabolism / Q000627:therapeutic use; D007700:Kinetics; D009428:Netilmicin / Q000627:therapeutic use; D010406:Penicillins / Q000627:therapeutic use; D012853:Sisomicin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D010406:Penicillins; D009428:Netilmicin; D000667:Ampicillin; D000583:Amikacin; D012853:Sisomicin
Anwendungsmöglichkeiten neuerer Antibiotika.