Forssman-like antibody levels in sera of patients with lung cancer.
Sera of normal individuals or patients with lung cancer were assayed for Forssman-like antibody by a quantitative and specific method using ethylenediaminetetraacetate-containing buffer to inactivate complement in the test serum. It was shown that although Forssman-like antibody levels were distributed widely, (a) the levels of young (20 to 45 years of age) normal subjects of Blood Groups A and AB were lower than those of Blood Groups O and B, (b) the levels of old (60 to 80 years of age) normal subjects were lower than those of young normal subjects of Blood Groups O and B, and (c) the levels of old lung cancer patients were lower when compared to age-matched normal individuals of their blood group.
D000017:ABO Blood-Group System; D000328:Adult; D000367:Age Factors; D000368:Aged; D000912:Antibodies, Neoplasm / Q000032:analysis*; D000936:Antigen-Antibody Complex; D003165:Complement System Proteins; D005577:Forssman Antigen / Q000276:immunology*; D006461:Hemolysis; D006358:Hot Temperature; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000276:immunology*; D008875:Middle Aged
D000017:ABO Blood-Group System; D000912:Antibodies, Neoplasm; D000936:Antigen-Antibody Complex; D003165:Complement System Proteins; D005577:Forssman Antigen