title: Iosefamate meglumine: an iodinated contrast agent for hepatic computed tomography scanning.
abstract: Iosefamate meglumine, a water-soluble, iodinated compound which is chemically and pharmacologically similar to iodipamide, was studied as a contrast agent for hepatic CT scanning in dogs. The difference between the CT attenuation number of liver and blood increased by 16 EMI units after intravenous injection of iosefamate 150 mg l/kg. The agent may prove useful in improving the CT detection of isodense tumors within the liver.
mesh_terms: D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D007458:Iodipamide / Q000031:analogs & derivatives*; D008107:Liver Diseases / Q000000981:diagnostic imaging*; D008536:Meglumine / Q000031:analogs & derivatives / Q000494:pharmacology; D014057:Tomography, X-Ray Computed
chemical_list: C020374:iosefamate meglumine; D008536:Meglumine; D007458:Iodipamide