title: [Benzylpenicillin-induced leucopenia in subacute bacterial endocarditis (author's transl)].
abstract: In the high-dose benzylpenicillin treatment of subacute bacterial endocarditis leucopenia can develop in rare cases. Often it is paralleled by anemia, sometimes also by a decrease in the number of platelets. Myalgia, gastric discomfort, or a sore threat deserve interest as premonitory symptoms. In every case this treatment inevitably needs through hematologic control.
mesh_terms: D000328:Adult; D004698:Endocarditis, Subacute Bacterial / Q000188:drug therapy*; D006801:Humans; D007970:Leukopenia / Q000139:chemically induced*; D008297:Male; D009135:Muscular Diseases / Q000139:chemically induced; D010146:Pain / Q000139:chemically induced; D010400:Penicillin G / Q000009:adverse effects* / Q000627:therapeutic use; D013272:Stomach Diseases / Q000139:chemically induced; D013921:Thrombocytopenia / Q000139:chemically induced
chemical_list: D010400:Penicillin G
vernacular_title: Penicillin-G-induzierte Leukopenie bei Endocarditis lenta.