Quantitative effect of theophylline anhydrous on exercise-induced asthma after maximal physical effort.
The quantitative effects of theophylline anhydrous upon exercise-induced asthma (EIA) were evaluated in asthmatic children. Theophylline inhibits EIA after maximal physical effort, increases tolerance to exercise and exerts a greater inhibitory effect upon larger than smaller airways. Its inhibitory effect seems not to be related to plasma theophylline levels.
D000293:Adolescent; D001249:Asthma / Q000188:drug therapy*; D001250:Asthma, Exercise-Induced / Q000188:drug therapy*; D002648:Child; D004305:Dose-Response Relationship, Drug; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008450:Maximal Midexpiratory Flow Rate; D010366:Peak Expiratory Flow Rate; D005082:Physical Exertion; D012129:Respiratory Function Tests; D013806:Theophylline / Q000097:blood / Q000627:therapeutic use*
D013806:Theophylline