title: [Effect of hyperoxia on oxygen tension in the blood and brain tissue].
abstract: Changes of the oxygen tension in the surface layers of cerebral cortex (PtO2) and arterial blood (PaO2) in the conditions of hyperoxia occurred in anesthetized rabbits: raising of O2 partial pressure in altitude chamber to 1.0 and 2.0 kgs/cm2 increased PaO2 from 76.5 +/- 11.4 mm Hg to 472.3 +/- 63.1 and 1138.0 +/- 79.4 mm Hg respectively. Raising of O2 partial pressure in altitude chamber from 0.2 to 6.0 kgs/cm2 increased PtO2 from 34.9 +/- 12.0 to 1087.5 +/- 149.8 mm Hg. Obvious defence reactions of the organism developed at the moment of transition from air breathing to pure oxygen breathing under the pressure of 1.0 kgs/cm2. High effectiveness of these reactions preserved with the raising of pressure to 3.0 kgs/cm2 and weakened with the further raising of pressure to 4.0-6.0 kgs/cm2. With prolongation of exposure to the 2.0-3.0 kgs/cm2 pressure the defence reactions slackened as well.
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000032:analysis*; D006931:Hyperbaric Oxygenation; D010100:Oxygen / Q000032:analysis / Q000097:blood; D011817:Rabbits; D012119:Respiration
chemical_list: D010100:Oxygen
vernacular_title: Vliianie giperoksii na napriazhenie kisloroda v krovi i tkani mozga.