[Enzymatic mechanisms of the oncolysis by Clostridium oncolyticum M 55 ATCC 13.732 (author's transl)].
After a short review of older attempts at explanation of the oncolysis by Cl. oncolyticum M 55 a new theory will be presented. In connection with new results of enzymological investigations the metabolic correlations between the tumor cell and the vegetative clostridial cell and the consequences of the results for an oncolytic therapy will be demonstrated.
D000936:Antigen-Antibody Complex; D000942:Antigens, Bacterial; D001920:Bradykinin / Q000378:metabolism; D003013:Clostridium / Q000201:enzymology / Q000378:metabolism*; D006801:Humans; D006861:Hydrogen Peroxide / Q000096:biosynthesis; D009369:Neoplasms / Q000201:enzymology*; D010447:Peptide Hydrolases / Q000096:biosynthesis / Q000378:metabolism; D013171:Spores, Bacterial
D000936:Antigen-Antibody Complex; D000942:Antigens, Bacterial; D006861:Hydrogen Peroxide; D010447:Peptide Hydrolases; D001920:Bradykinin
Enzymatische Mechanismen der Onkolyse durch Clostridium oncolyticum M 55 ATCC 13.732.