title: [Effects of gonad-inhibiting factor from the brain upon morphology and metabolism in germ cells and sexula somatic cells of nemertines (author's transl)].
abstract: After the deprivation of gonad-inhibiting factor (GIF) from the brain in adult Nemertines of both sexes, the sexual characters appear and/or grow rapidly. Very early, RNA synthesis is promoted in young oocytes, DNA synthesis is increased in spermatogonia and primary spermatocytes and protein synthesis is significantly increased in germ cells and sexual somatic cells. The brain origin of GIF suggests a polypeptide nature whereas its effects are those of sex steroid hormones in Vertebrates. GIF could be a regulating hormone which would inhibit the secretion of tropic hormone(s) produced by unknown cells in proximity to the sexual targets.
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D005854:Germ Cells / Q000378:metabolism*; D006728:Hormones / Q000502:physiology*; D010986:Platyhelminths / Q000502:physiology*; D012741:Sexual Maturation
chemical_list: D006728:Hormones
vernacular_title: Effets du facteur cérébralgonado-inhibiteur (FGI) sur la morphologie et le métabolisme des cellules sexualisées germinales et somatiques des nemertiens.