[Lipid peroxidation, peroxidase activity and glutathione antiperoxide systems in rat tissues under conditions of high altitude hypoxia].
The content of lipid peroxides in rat tissues does not vary essentially under conditions of high altitude hypoxia. The peroxidase activity undergoes fluctuating changes with a significant increase in brain tissues. Among the enzymes of the glutathione antiperoxide system only the glutathione peroxidase activity shows a 5-10-fold decrease. As assumption is advanced that under conditions of hypoxia there occurs an inhibition of the glutathione antiperoxide system, which prevents the lipid peroxides level in tissues from falling.
D000531:Altitude; D000818:Animals; D005979:Glutathione Peroxidase / Q000378:metabolism*; D000860:Hypoxia / Q000378:metabolism*; D007700:Kinetics; D050356:Lipid Metabolism; D009928:Organ Specificity; D010544:Peroxidases / Q000378:metabolism*; D010545:Peroxides / Q000378:metabolism*; D051381:Rats
D010545:Peroxides; D010544:Peroxidases; D005979:Glutathione Peroxidase
Peroksidatsiia lipidov, peroksikaznaia aktivnost' i sostoianie glutationovoĭ antiperekisnoĭ sistemy v tkaniakh krys pri vysotnoĭ gipoksii.