title: Analysis of fludrocortisone acetate and its solid dosage forms by high-performance liquid chromatography.
abstract: A newly developed reversed-phase high-performance liquid chromatographic assay and test method for determining content uniformity are described for fludrocortisone acetate. The method is stability indicating and separates most known degradation products and impurities. In addition, the method is simple, sensitive, accurate, and relatively free of interferences. The coefficient of variation for multiple weight assays is between 0.3 and 1.8%.
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D005438:Fludrocortisone / Q000032:analysis*; D006358:Hot Temperature; D008722:Methods; D013607:Tablets / Q000032:analysis
chemical_list: D013607:Tablets; D005438:Fludrocortisone