Underlying disorders responsible for the neonatal deaths associated with low Apgar Scores.
Data from a large study were used to determine the frequency of fatal disorders associated with low Apgar scores. 5-min scores had the best correlation with mortality rates. Death rates were more than ten times greater with abnormal than with normal 5-min scores. This difference was only 3-fold for 1-min values. Amniotic fluid infections were responsible for nearly half of the deaths in preterm and 24% of the deaths in term neonates with 5-min Apgar scores 0--6. The respective values for disorders that cause antenatal hypoxia were 25 and 24% and for major congenital anomalies, 7 and 28%.
D000037:Abruptio Placentae; D000653:Amniotic Fluid; D001034:Apgar Score; D000013:Congenital Abnormalities / Q000401:mortality; D005260:Female; D005311:Fetal Hypoxia / Q000401:mortality; D005322:Premature Rupture of Fetal Membranes; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000401:mortality*; D007234:Infant, Premature; D007744:Obstetric Labor Complications; D007752:Obstetric Labor, Premature; D010922:Placenta Diseases; D010923:Placenta Previa; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious