[Effect of hydrocortisone on intensity of (3H)methionine incorporation into rat polyribosome and cytosol proteins in alloxan diabetes].
Alloxane diabetes decreases the intensity of [3H] methionine incorporation into total proteins of the liver cells polyribosomes and cytosol. Administration of hydrocortisone for seven days aggravate this disturbances and insulin injections level them. A combined administration of both hormones weakens the negative effect of hydrocortisone on the intensity of the amino acid incorporation and the glucose level in blood.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003600:Cytosol / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D006854:Hydrocortisone / Q000494:pharmacology*; D007328:Insulin / Q000494:pharmacology; D008099:Liver / Q000378:metabolism*; D008297:Male; D008715:Methionine / Q000378:metabolism; D011132:Polyribosomes / Q000187:drug effects / Q000378:metabolism*; D014176:Protein Biosynthesis / Q000187:drug effects*; D051381:Rats; D012269:Ribosomal Proteins / Q000096:biosynthesis
D001786:Blood Glucose; D007328:Insulin; D012269:Ribosomal Proteins; D008715:Methionine; D006854:Hydrocortisone
Vliianie gidrokoptizona na intensivnost' vkliucheniia (3H) metionina v belki polisom i tsitozola pecheni krys pri alloksanovom dnabete.