title: Upper airways obstruction with bilateral vocal cord paralysis.
abstract: In ten patients with bilateral vocal cord paralysis, we demonstrated variable extrathoracic airway obstruction. The ratio of forced expiratory flow at 50 percent vital capacity to forced inspiratory flow at the same lung volume (VE50/VI50) was 1.65 +/- 0.77 (mean +/- 1 SD). There was marked variability of inspiratory flow obstruction with a mean VI50 of 1.63 +/- 0.75 liters/ sec and a range from 0.9 liters/sec to 3.2 liters/sec. Nine of the ten patients required tracheostomy for symptoms of dyspnea. Follow-up flow volume loops were obtained to document the effects of surgical intervention and tracheostomy.
mesh_terms: D000328:Adult; D000368:Aged; D000402:Airway Obstruction / Q000209:etiology* / Q000503:physiopathology; D004417:Dyspnea / Q000209:etiology / Q000601:surgery; D005260:Female; D005540:Forced Expiratory Flow Rates; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D014140:Tracheotomy; D014797:Vital Capacity; D014826:Vocal Cord Paralysis / Q000150:complications* / Q000503:physiopathology