[Comparative effects of tamoxifen and estorgens on the induction of progesterone receptors and uterine growth in rats].
Effects of prolonged administration (7 days) of Tamoxifen (Tx: 100 micrograms/day), oestradiol-17 beta (E2; 1 microgram/day) and oestriol (E3; silastic capsules) on the uterine weight, protein, DNA and progesterone receptor (RP) content of prepubertal rats have been studied. It has been observed when compared with E2 that Tx induces a dissociated action after two days of administration; the RP content is still increasing when the other parameters are at a constant level. E3 has a similar action to E2.
D000818:Animals; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D051381:Rats; D011980:Receptors, Progesterone / Q000187:drug effects*; D013629:Tamoxifen / Q000494:pharmacology*; D013997:Time Factors; D014599:Uterus / Q000187:drug effects* / Q000254:growth & development
D011980:Receptors, Progesterone; D013629:Tamoxifen; D004958:Estradiol
Effets comparés du tamoxigène et des oestrogènes sur l'induction des récepteurs de la progesterone et la croissance de l'utérus de rate.