Laboratory evaluation of amikacin susceptibility testing by the AutoBac I system.
A total of 319 clinical isolates were compared for amikacin susceptibility by AutoBac I and Bauer-Kirby disk diffusion methods. There was an overall agreement of 98.5% between AutoBac I and Bauer-Kirby. An additional 23 strains resistant to amikacin, obtained from Bristol Laboratories, registered a 65% overall agreement. The sensitivity readings differed between the two methods for 13 organisms: 11 were minor discrepancies, intermediate by one of the two methods, and 2 were very major discrepancies, resistant by disk diffusion and susceptible by AutoBac I.
D000583:Amikacin / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D006801:Humans; D007612:Kanamycin / Q000031:analogs & derivatives*; D008826:Microbial Sensitivity Tests / Q000379:methods*; D013045:Species Specificity
D007612:Kanamycin; D000583:Amikacin