[Study of the texture of furosemid tablets. Part 2 (author's transl)].
The authors studied the alterations of the texture and of the physical properties of Furosemid tablets, which are prepared with the aid of hydroxypropylcellulose mucilage, that occur during storage. Klucel MF mucilage proved to be a very good binding agent. Though the film bursted on drying during storage, by which the pore volume of the tablets increased, the mechanical strength remained almost unchanged. The cause of this is the formation of solid bridges.
D002482:Cellulose; D055598:Chemical Phenomena; D002626:Chemistry, Pharmaceutical; D002627:Chemistry, Physical; D005079:Excipients; D005665:Furosemide / Q000032:analysis; D008855:Microscopy, Electron, Scanning; D013499:Surface Properties
D005079:Excipients; D005665:Furosemide; D002482:Cellulose
Untersuchung der Textur von Furosemid-Tabletten. Teil 2.