Release of lipoteichoic acid from Streptococcus sanguis: stimulation of release during penicillin treatment.
The spontaneous and the penicillin-stimulated release of water-soluble, glycerol-labeled polymers was compared in Streptococcus sanguis. In contrast to the spontaneous release occurring in exponentially growing or stationary-phase bacteria, penicillin-treated cells released the bulk of these polymers, and they were not replenished by synthesis during antibiotic treatment. Furthermore, a major portion of the extracellular polymers was characterized as acylated lipoteichoic acid.
D004912:Erythrocytes / Q000276:immunology; D006017:Glycolipids / Q000276:immunology / Q000378:metabolism*; D006386:Hemagglutination Tests; D006801:Humans; D010400:Penicillin G / Q000494:pharmacology*; D013298:Streptococcus sanguis / Q000187:drug effects* / Q000276:immunology; D013682:Teichoic Acids / Q000276:immunology / Q000378:metabolism*
D006017:Glycolipids; D013682:Teichoic Acids; D010400:Penicillin G