Inhibition of cimetidine-induced hyperprolactinaemia by pretreatment with levodopa or bromocriptine.
A single i.v. administration of cimetidine, an histamine receptor antagonist, produced a significant increase in serum prolactin (PRL) levels in fifteen normal men. This effect was suppressed by pretreatment with levodopa or bromocriptine.
D000328:Adult; D001971:Bromocriptine / Q000494:pharmacology*; D002927:Cimetidine / Q000494:pharmacology*; D006146:Guanidines / Q000494:pharmacology*; D006801:Humans; D007980:Levodopa / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D011388:Prolactin / Q000097:blood*
D006146:Guanidines; D001971:Bromocriptine; D007980:Levodopa; D002927:Cimetidine; D011388:Prolactin