[Short-term oral chemoprophylaxis before intestine surgery. Quantitative determination of bacteria and fungi in stool specimens (author's transl)].
The methods of quantitative analysis of aerobe and anaerobe microbes and fungi stool specimens are described. The results of the studies in health people are compared to the results in patients undergoing surgical treatment of intestinal tract. A group of these patients received Neomycin and Bacitracin orally as short-time chemoprophylaxis to diminish possible woundinfection and/or sepsis. After oral medication germs as Bifidobacterium, Bacteroides and Clostridium (not Cl. perfringens) are reduced or lost, Veillonella, Eubacterium, Fusiformis, Peptostreptococcus and Lactobacillus were suppressed. Resistant strains of E. coli and Enterococci increased to high concentration/g faeces. After treatment the rate of gram-negative bacteria resistant to Neomycin increased. This might be of epidemiologically importance for the distribution of microbes resistant to Neomycin and other aminoglycosides as Klebsiella, Candida spec. and Torulopsis.
D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001414:Bacitracin / Q000008:administration & dosage; D001419:Bacteria / Q000302:isolation & purification*; D005243:Feces / Q000382:microbiology*; D005658:Fungi / Q000302:isolation & purification*; D006801:Humans; D007410:Intestinal Diseases / Q000601:surgery; D008722:Methods; D009355:Neomycin / Q000008:administration & dosage; D011300:Preoperative Care; D013530:Surgical Wound Infection / Q000517:prevention & control*
D000900:Anti-Bacterial Agents; D001414:Bacitracin; D009355:Neomycin
Kurzfristige orale Chemoprophylaxe vor Operationen am Darm. Aussagemöglichkeiten bei der quantitativen Untersuchung der Stuhlflora auf Bakterien und Pilze.