Effects of ageing on the pharmacokinetics of pancuronium.
The effects of age on the pharmacokinetics of pancuronium were investigated. The distribution volume of pancuronium did not appear to be age-dependent, but elimination of the drug decreased with increasing age. The clinical implications of these findings are discussed.
D000328:Adult; D000368:Aged; D000375:Aging; D000768:Anesthesia, General; D001835:Body Weight; D005260:Female; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D010197:Pancuronium / Q000378:metabolism*
D010197:Pancuronium