Location of the force of wound contraction.
Contractile fibroblasts were found on electron microscopy to be distributed throughout the substance of contracting pig and rat wounds. The force of wound contraction is probably caused by these cells contracting and pulling on each other and on the surrounding stroma. This evidence suggests that the pull theory of wound contraction is correct.
D000818:Animals; D005347:Fibroblasts / Q000473:pathology; D006097:Granulation Tissue / Q000473:pathology; D051381:Rats; D013552:Swine; D013997:Time Factors; D014945:Wound Healing