title: Treatment of basal cell carcinoma of the skin with 5-fluorouracil ointment. A 10-year follow-up study.
abstract: During the period 1966-1968, 88 patients with a total of 95 basal cell carcinomas were treated with 5% 5-fluorouracil ointment. A follow-up study carried out from November 1977 to January 1978 revealed a total of 12 recurrences in 56 surviving patients with 56 basal cell carcinomas. The recurrence rate is thus 21.4%. It is concluded that there is hardly any indication for using 5-fluorouracil in local treatment of nodular basal cell carcinoma.
mesh_terms: D000287:Administration, Topical; D002280:Basal Cell Carcinoma / Q000188:drug therapy* / Q000601:surgery; D003475:Curettage; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D009364:Neoplasm Recurrence, Local; D009824:Ointments; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000601:surgery
chemical_list: D009824:Ointments; D005472:Fluorouracil