The effect on fertility of vaccinating female sheep with biochemically defined fractions of ram spermatozoa.
Sixty sheep were vaccinated with six biochemically defined fractions of ram spermatozoa obtained by differential extraction procedures with 0.1% Triton X-100 and 2 M MgCl2, followed by ion-exchange chromatography. No one group showed a significant reduction in fertility as compared with the controls, but there was some evidence that MgCl2 extracts were not more potent infertility-inducing agents. Some of the mechanisms by which the immune response could influence fertility are also discussed.
D000818:Animals; D000917:Antibody Formation; D005591:Chemical Fractionation; D005260:Female; D005298:Fertility; D008274:Magnesium; D008297:Male; D011247:Pregnancy; D012756:Sheep; D013094:Spermatozoa / Q000276:immunology*; D014611:Vaccination
D008274:Magnesium