Peripheral lymphocyte culture in the diagnosis of drug induced liver injury.
In order to evaluate the usefulness of the peripheral lymphocyte culture method for the diagnosis of drug-induced liver injury, a study was carried out on 21 cases of drug-induced liver injury (Group A). Nine cases in Group A showed a positive lymphocyte stimulation test. Out of 9 cases which showed positive stimulation six cases were cholestatic type of liver injury, and the remaining three were of hepatitic type. The results suggest that peripheral lymphocyte culture method is a useful method for diagnosis of drug-induced liver injury.
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000995:Antitubercular Agents / Q000494:pharmacology; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D008213:Lymphocyte Activation; D008297:Male
D000900:Anti-Bacterial Agents; D000995:Antitubercular Agents