title: Two cases of rubella infection with cardiac involvement.
abstract: During the prevalence of rubella infection in Japan in 1975, we experienced 2 cases complicated with cardiac involvement: a 40-year-old housewife and a 52-year-old man. These 2 cases showed enlarged cardiac silhouettes and bilateral pleural effusion on the chest X-ray films. Pericardial effusion was demonstrated by echocardiogram and cardiac RI pool scintigram. A myocardial biopsy specimen showed slight cell infiltration in Case 1. The anti-rubella antibody titer rose from 128x to 4096x in Case 1 and from 265x to 1024x in Case 2. From these findings Case 1 was diagnosed as rubella pancarditis and Case 2 as pleuropericarditis. Only 4 cases with the cardiac involvement of rubella was reported in the past.
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D004696:Endocarditis / Q000209:etiology; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000209:etiology; D010493:Pericarditis / Q000209:etiology; D010998:Pleurisy / Q000209:etiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012409:Rubella / Q000150:complications* / Q000175:diagnosis; D012412:Rubella virus / Q000276:immunology
chemical_list: D000914:Antibodies, Viral