Distribution of the multiple molecular forms of glucose-6-phosphate dehydrogenase in different physiological states.
The distribution of the multiple molecular forms of rat liver and mammary gland glucose-6-phosphate dehydrogenase was determined by electrophoresis on 5% polyacrylamide gels. In both of these organs, changes in the distribution of enzyme activity among the several forms was slight even when approximately 20- to 40-fold changes in enzyme specific activity were achieved by fasting-refeeding experiments (for liver) or during pregnancy and lactation (for mammary gland). It was concluded that the induction of glucose-6-phosphate dehydrogenase in these two organs occurs without any major redistribution among the multiple molecular forms of this enzyme.
D000818:Animals; D005215:Fasting; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism*; D007527:Isoenzymes / Q000378:metabolism*; D007774:Lactation; D008099:Liver / Q000201:enzymology*; D008321:Mammary Glands, Animal / Q000201:enzymology*; D008970:Molecular Weight; D011247:Pregnancy; D051381:Rats
D007527:Isoenzymes; D005954:Glucosephosphate Dehydrogenase