title: Effects of influenza vaccination on the peripheral airways of healthy human volunteers.
abstract: Forty-two volunteers (15 of them cigarette smokers) were studied to determine the effects on the airways that might result from immunization with killed influenza virus vaccine. The forced vital capacity, the forced expiratory volume in one second, the maximal expiratory flows at 50 and 75 percnet of vital capacity, and the volume isoflow were determined before and at 24, 48, and 72 hours and one and two weeks after vaccination. For both smokers and nonsmokers, there were no significant changes in the results of these tests of pulmonary function following vaccination.
mesh_terms: D000328:Adult; D005260:Female; D005540:Forced Expiratory Flow Rates; D006801:Humans; D007252:Influenza Vaccines / Q000494:pharmacology*; D008168:Lung / Q000502:physiology*; D008297:Male; D008448:Maximal Expiratory Flow Rate; D008875:Middle Aged; D012907:Smoking / Q000150:complications; D013997:Time Factors; D014109:Total Lung Capacity; D014611:Vaccination; D014797:Vital Capacity
chemical_list: D007252:Influenza Vaccines