title: Light-evoked changes in chick optic lobe adenylate-cyclase.
abstract: The effects of exposure to 48 h darkness and to stroboscope stimulation on chick optic lobe adenylate-cyclase activity were studied. A significant decrease in adenylate-cyclase after 48 h exposure to darkness occurred with return to normal values after re-exposure to light. Stroboscope stimulation for 3 min produced instead a marked increase in optic lobe adenylate-cyclase. Present experiments suggest that cAMP may serve as inhibitory messenger in synaptic transmission along central visual pathways.
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D002645:Chickens / Q000378:metabolism*; D003624:Darkness; D008027:Light; D003336:Tectum Mesencephali / Q000201:enzymology*; D013997:Time Factors
chemical_list: D000262:Adenylyl Cyclases