Ureteropelvic junction obstruction and sibling uropathology.
Thirty-seven siblings of 20 probands with ureteropelvic junction obstruction were evaluated with an intravenous pyelogram (IVP) and a voiding cystourethrogram (VCUG). Fourteen of 37 (38 per cent) had uropathology and 13 of 14 (93 per cent) required some form of therapy. Fifty-five per cent of the families had an additional child with uropathology. The recommendation concluded from this and a previous study on reflux is that all siblings of children with uropathology be investigated with an IVP and VCUG regardless of age or sex.
D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D014517:Ureteral Obstruction / Q000000981:diagnostic imaging / Q000235:genetics*; D014524:Urethral Obstruction / Q000235:genetics; D014552:Urinary Tract Infections / Q000235:genetics; D014567:Urography; D014718:Vesico-Ureteral Reflux / Q000000981:diagnostic imaging / Q000235:genetics