Fertility and cancer therapy.
With increased survival of increasing numbers of cancer patients as a result of therapy, the consequences, early and late, of the therapies must be realized. It is the treating physician's duty to preserve as much reproductive potential as possible for patients, consistent with adequate care. With radiotherapy this means shielding the gonads as much as possible, optimal but not excessive doses and fields, oophoropexy, or sperm collection and storage prior to irradiation. With chemotherapy it means the shortest exposure to drugs consistent with best treatment and prior to therapy the collection and storage of sperm where facilities are available. At present this is still an experimental procedure. Artificial insemination for a couple when the male has received cancer therapy is another alternative. Finally, it is the responsibility of physicians caring for patients with neoplasms to be knowledgeable about these and all other effects of therapy so that patients may be counseled appropriately and understand the implications of therapy for their life.
D000970:Antineoplastic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007246:Infertility / Q000209:etiology*; D008297:Male; D009369:Neoplasms / Q000628:therapy*; D010053:Ovary / Q000187:drug effects / Q000528:radiation effects; D010063:Ovum / Q000187:drug effects / Q000528:radiation effects; D011247:Pregnancy; D011878:Radiotherapy / Q000009:adverse effects*; D013091:Spermatogenesis / Q000187:drug effects / Q000528:radiation effects; D013737:Testis / Q000187:drug effects / Q000528:radiation effects
D000970:Antineoplastic Agents