title: Histones biosynthesis and turnover in epithelial lens cells cultured in vitro.
abstract: "Histone synthesis was compared in epithelial lens cells during exponential growth and in the stationary phase brought by contact inhibition. Double labelling experiments with 3H-lysine and 14C-lysine show a net turnover of histone H1 independent of DNA replication. The nucleosome core histones seem to turn over also, but much more slowly than H1".
mesh_terms: D000818:Animals; D002417:Cattle; D002455:Cell Division; D002478:Cells, Cultured; D004847:Epithelial Cells; D004848:Epithelium / Q000378:metabolism; D006657:Histones / Q000096:biosynthesis / Q000378:metabolism*; D007399:Interphase; D007908:Lens, Crystalline / Q000166:cytology / Q000378:metabolism*
chemical_list: D006657:Histones