Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D003907:Dexamethasone / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000096:biosynthesis; D006168:Guinea Pigs; D006854:Hydrocortisone / Q000494:pharmacology; D008168:Lung / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D010740:Phospholipases / Q000037:antagonists & inhibitors*; D014176:Protein Biosynthesis; D013928:Thromboxane A2 / Q000096:biosynthesis*; D013931:Thromboxanes / Q000096:biosynthesis*; D014221:Triamcinolone / Q000494:pharmacology
D000893:Anti-Inflammatory Agents; D004791:Enzyme Inhibitors; D013931:Thromboxanes; D014221:Triamcinolone; D013928:Thromboxane A2; D003907:Dexamethasone; D010740:Phospholipases; D006854:Hydrocortisone