[The mycoplasma-pneumonia. A model for the study of the pathogenesis of infectious diseases (author's transl)].
The known mechanisms of pathogenicity of Mycoplasma pneumoniae are discussed. In addition, evidence is provided for the participation of the immune system in the pathogenesis of M. pneumoniae disease. In a working hypothesis the stimulation of a protective and/or a reactive immune response is postulated, depending on the predisposition of the host, the infecting dose, the frequency of contact and the virulence of the organisms. Because well studied animal models are available, the Mycoplasma-Pneumonia is well suited to investigate the pathogenesis of infections caused by bacteria and the defense of the host.
D000818:Animals; D006224:Cricetinae; D004195:Disease Models, Animal; D006168:Guinea Pigs; D009174:Mycoplasma / Q000276:immunology / Q000472:pathogenicity; D009175:Mycoplasma Infections / Q000209:etiology* / Q000276:immunology; D011014:Pneumonia / Q000209:etiology* / Q000276:immunology; D014774:Virulence
Die Mycoplasma-Pneumonie. Ein Modell zum Studium der Pathogenese von Infektionskrankheiten.