title: Mechanism of pyruvate inhibition of kidney pyruvate dehydrogenasea kinase and synergistic inhibition by pyruvate and ADP.
mesh_terms: D000244:Adenosine Diphosphate / Q000494:pharmacology*; D000255:Adenosine Triphosphate; D000818:Animals; D001667:Binding, Competitive; D002417:Cattle; D003999:Dichloroacetic Acid / Q000494:pharmacology; D004357:Drug Synergism; D007668:Kidney / Q000378:metabolism*; D007700:Kinetics; D008433:Mathematics; D011485:Protein Binding; D011768:Pyruvate Dehydrogenase Complex / Q000037:antagonists & inhibitors*; D011770:Pyruvate Kinase / Q000037:antagonists & inhibitors*; D011773:Pyruvates / Q000494:pharmacology*
chemical_list: D011768:Pyruvate Dehydrogenase Complex; D011773:Pyruvates; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D003999:Dichloroacetic Acid; D011770:Pyruvate Kinase