[Liver enlargement induced by oxythioquinox: effect of the fat content of the diet (author's transl)].
The relationship between the level of lipid calories in the diet and the effects of oxythioquinox, administered at 200 mg/kg fresh food, for 35 days, was studied on the liver enlargment of rat. The results show that the level lipid calories itself have no effect since, in the treated animals, the liver enlargement is due part to an increase of the water content and part to an increase of the size of the cells.
D000818:Animals; D002784:Cholesterol / Q000378:metabolism; D004247:DNA / Q000378:metabolism; D004041:Dietary Fats / Q000494:pharmacology*; D006529:Hepatomegaly / Q000139:chemically induced*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D011810:Quinoxalines / Q000494:pharmacology*; D012313:RNA / Q000378:metabolism; D051381:Rats
D004041:Dietary Fats; D011810:Quinoxalines; D012313:RNA; C005266:quinomethionate; D004247:DNA; D002784:Cholesterol
Hypertrophie du foie provoquée par l'oxythioquinox: influence du traux de lipides de la ration alimentaire.