Interstrain variation of murine arylsulfatase C.
A method has been developed for the assay of arylsulfatase C in tissue extracts containing arylsulfatases A and B. Significant variation of enzyme activity was observed among 26 inbred murine strains. Activity differences were apparent at all stages evaluated between 1 and 70 days postnatal age. Arylsulfatase C from representative high- and low-activity strains exhibited similar Michaelis constants, temperature optima, pH optima, thermostabilities and inhibitor profiles.
D000375:Aging; D000818:Animals; D001192:Arylsulfatases / Q000378:metabolism*; D001921:Brain / Q000201:enzymology; D007668:Kidney / Q000201:enzymology; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains / Q000378:metabolism*; D013045:Species Specificity; D013429:Sulfatases / Q000378:metabolism*
D013429:Sulfatases; D001192:Arylsulfatases