title: Severe mannitol-induced hyponatremia complicating transurethral prostatic resection.
abstract: A case is presented in which the absorption of mannitol irrigation solution across prostatic veins resulted in severe hyponatremia in a patient undergoing transurethral prostatic resection. Since hyposmolality of the extracellular fluid was not seen because of the presence of mannitol the patient was asymptomatic despite a rapid decrease in the serum sodium concentration to 99 mEq./l. The importance of distinguishing dilutional hyponatremia from hyponatremia with normal or elevated osmolality is discussed.
mesh_terms: D000368:Aged; D006801:Humans; D007010:Hyponatremia / Q000209:etiology*; D008297:Male; D008353:Mannitol / Q000009:adverse effects*; D009994:Osmolar Concentration; D011183:Postoperative Complications / Q000209:etiology*; D011468:Prostatectomy
chemical_list: D008353:Mannitol