title: Genetic differences in the mitogenic response of peripheral blood lymphocytes in the chicken.
abstract: The mitogenic responses of chicken peripheral blood lymphocytes were compared in two partially inbred chicken lines and in their hybrids. The lymphocytes of line P chickens showed a higher phytohaemagglutinin (PHA) response than those of line V chickens and (P X V)F1 hybrids. The Con A responses were of the same magnitude in all chicken lines. The higher PHA response in line P chickens was not sex-linked, apparently was not associated with the major histocompatibility complex and it did not correlate with immunoglobulin G allotypes.
mesh_terms: D000818:Animals; D002645:Chickens / Q000097:blood / Q000235:genetics*; D003208:Concanavalin A / Q000494:pharmacology; D008040:Genetic Linkage; D007126:Immunoglobulin Allotypes / Q000235:genetics; D008214:Lymphocytes / Q000276:immunology*; D008285:Major Histocompatibility Complex; D008934:Mitogens / Q000494:pharmacology*; D010641:Phenotype; D010835:Phytohemagglutinins / Q000494:pharmacology; D012730:Sex Chromosomes
chemical_list: D007126:Immunoglobulin Allotypes; D008934:Mitogens; D010835:Phytohemagglutinins; D003208:Concanavalin A