[Effect of several diuretics on ischemic damage to the kidneys].
Furosemide, etacrynic acid and mannitol administered to the survival of rats. However, these drugs prove ineffective in the event they are indicated after the action of the ischemic factor is discontinued. Etacrynic acid and novurit inhibit the functional activity of isolated mitochondria incubated under hypoxia and at a temperature of 37 degrees C.
D000818:Animals; D004232:Diuretics / Q000494:pharmacology / Q000627:therapeutic use*; D004976:Ethacrynic Acid / Q000627:therapeutic use; D005665:Furosemide / Q000627:therapeutic use; D066298:In Vitro Techniques; D007511:Ischemia / Q000188:drug therapy* / Q000517:prevention & control; D007668:Kidney / Q000098:blood supply*; D008353:Mannitol / Q000627:therapeutic use; D008928:Mitochondria / Q000187:drug effects; D009941:Organomercury Compounds / Q000008:administration & dosage / Q000627:therapeutic use; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats; D014494:Unithiol / Q000627:therapeutic use
D004232:Diuretics; D009941:Organomercury Compounds; D008353:Mannitol; D014494:Unithiol; D005665:Furosemide; D004976:Ethacrynic Acid
Vliianie nekotorykh diuretikov na ishemicheskoe povrezhdenie pochek.