A comparison of the bronchodilator effects of terbutaline, Tedral and the simultaneous use of both agents.
A modified double-blind study in 14 asthmatic patients had demonstrated that oral terbutaline (5 mg) resulted in significantly greater bronchodilation than did Tedral. Simultaneous ingestion of terbutaline and Tedral resulted in significantly greater bronchodilation than after either agent alone, which supports the concomitant use of beta-2 agonists and theophylline agents when treating patients with airflow obstruction.
D000403:Airway Resistance / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D004809:Ephedrine / Q000627:therapeutic use*; D005541:Forced Expiratory Volume; D006801:Humans; D008450:Maximal Midexpiratory Flow Rate; D010634:Phenobarbital / Q000627:therapeutic use*; D011674:Pulse / Q000187:drug effects; D013726:Terbutaline / Q000627:therapeutic use*; D013806:Theophylline / Q000627:therapeutic use*; D014797:Vital Capacity
D013806:Theophylline; D004809:Ephedrine; D013726:Terbutaline; D010634:Phenobarbital