Genetic mapping of the locus controlling structural variations of murine C3 in the chromosome 17.
Backcross progeny, (NC X TF/GnLe)F1 X TF/GnLe, was tested for C3 allotype controlled by C3-1 and the expression of mutant gene tf, repeated loss and regrowth of hair. The recombination frequency between these two loci both located in chromosome 17 of the mouse was 24%. Taken together with our previous linkage data, C3-1 is now localized to a position 11 cm more distal than H-2 on chromosome 17.
D000818:Animals; D002874:Chromosome Mapping; D002875:Chromosomes; D003176:Complement C3 / Q000235:genetics*; D003433:Crosses, Genetic; D008040:Genetic Linkage; D014644:Genetic Variation; D006649:Histocompatibility Antigens / Q000235:genetics; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics*; D010641:Phenotype
D003176:Complement C3; D006649:Histocompatibility Antigens