Synthesis of a proposed thymic factor.
Less than Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn, a proposed serum thymic factor, has been synthesized. The protected precursor, less than Glu-Ala-Lys(i-Noc)-ser(Bzl)-Gln-Gly-Gly-Ser(Bzl)-Asn, was prepared by a combination of solid phase and solution methods. The benzyl blocking groups were removed by HF and the i-Noc blocking group was removed by catalytic hydrogenation.
D000595:Amino Acid Sequence; D008722:Methods; D009842:Oligopeptides / Q000138:chemical synthesis; D013951:Thymus Hormones / Q000138:chemical synthesis*
D009842:Oligopeptides; D013951:Thymus Hormones