title: Blood levels of sulfamethazine achieved in beef calves on medicated drinking water.
abstract: Studies on the use of sodium sulfamethazine in drinking water at three levels (572, 1028 and 1848 mg/L) were conducted in healthy weaned beef calves under similar dietary and environmental conditions. Blood sulfonamide levels greater than 5 mg/dl were attained with each treatment level but at different time intervals. The maximum levels in blood were achieved with the highest concentration in the water. However, a reduction in water intake caused a lower than anticipated dose of sulfamethazine. Under the conditions of the experiment the administration of sulfonamide in drinking water may be an effective means of mass medication of cattle.
mesh_terms: D000818:Animals; D002417:Cattle / Q000097:blood*; D004326:Drinking; D005260:Female; D012964:Sodium / Q000008:administration & dosage; D013418:Sulfamethazine / Q000008:administration & dosage / Q000097:blood*
chemical_list: D013418:Sulfamethazine; D012964:Sodium