Granuloma formation associated with subconjunctival injection of a corticosteroid in dogs.
In three dogs given a subconjunctival injection of methylprednisolone acetate for the treatment of ophthalmic disorders, a yellow mass developed at the injection site. Microscopic examination of each excised mass revealed circumscribed granulomatous inflammation surrounding a central core of amorphous foreign material.
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage* / Q000009:adverse effects; D000818:Animals; D003228:Conjunctiva; D003692:Delayed-Action Preparations; D004283:Dog Diseases / Q000139:chemically induced* / Q000473:pathology; D004285:Dogs; D005128:Eye Diseases / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D006099:Granuloma / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D007267:Injections / Q000009:adverse effects / Q000662:veterinary; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects
D000305:Adrenal Cortex Hormones; D003692:Delayed-Action Preparations; D008775:Methylprednisolone