title: The three-dimensional structure of tubulin protofilaments.
abstract: A three-dimensional image of tubulin protofilaments, reconstructed to 20 A resolution from electron micrographs of negatively stained zinc-induced sheets, has been used to generate an improved model for microtubule substructure. This model has been used to phase a reconstructed image from X-ray amplitudes, which is compatible with the electron microscope results.
mesh_terms: D003461:Crystallography; D006023:Glycoproteins; D046911:Macromolecular Substances; D008854:Microscopy, Electron; D008870:Microtubules / Q000648:ultrastructure*; D011485:Protein Binding; D014404:Tubulin; D014961:X-Ray Diffraction; D015032:Zinc / Q000494:pharmacology
chemical_list: D006023:Glycoproteins; D046911:Macromolecular Substances; D014404:Tubulin; D015032:Zinc