An unusual neoplasm of adipose tissue in a rat.
The light microscopic features of a spontaneous neoplasm of adipose tissue from a rat were suggestive of a mixed liposarcoma with a myxoid matrix. However, ultrastructurally, the cell characteristics were those of a hibernoma. These characteristics included cells containing lipid droplets of variable size, numberous pleomorphic mitochondria and close apposition to blood vessels. Lipofuscin granules and subplasmalemmal condensations were not observed ultrastructurally.
D000273:Adipose Tissue / Q000473:pathology; D000818:Animals; D005260:Female; D008067:Lipoma / Q000473:pathology / Q000662:veterinary*; D008080:Liposarcoma / Q000473:pathology / Q000662:veterinary*; D009369:Neoplasms / Q000473:pathology / Q000662:veterinary*; D051381:Rats; D012376:Rodent Diseases / Q000473:pathology*