title: The effect on fertility of vaccinating female sheep with biochemically defined fractions of ram spermatozoa.
abstract: Sixty sheep were vaccinated with six biochemically defined fractions of ram spermatozoa obtained by differential extraction procedures with 0.1% Triton X-100 and 2 M MgCl2, followed by ion-exchange chromatography. No one group showed a significant reduction in fertility as compared with the controls, but there was some evidence that MgCl2 extracts were not more potent infertility-inducing agents. Some of the mechanisms by which the immune response could influence fertility are also discussed.
mesh_terms: D000818:Animals; D000917:Antibody Formation; D005591:Chemical Fractionation; D005260:Female; D005298:Fertility; D008274:Magnesium; D008297:Male; D011247:Pregnancy; D012756:Sheep; D013094:Spermatozoa / Q000276:immunology*; D014611:Vaccination
chemical_list: D008274:Magnesium