[Effect of several anti-arrhythmic substances on ion currents in from atrium].
On trabeculae of the frog's atrium it is shown by the method of the potential fixation with the use of a double saccharose bridge that novocainamide, quinidine and oxylidine mainly reduce the steady output membrane current and virtually have no effect on the input peak current. And, conversely, novocain significantly suppresses the input peak current and affects but little the steady membrane current.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D001001:Anura; D002463:Cell Membrane Permeability / Q000187:drug effects; D006321:Heart / Q000187:drug effects*; D008564:Membrane Potentials / Q000187:drug effects; D011188:Potassium / Q000378:metabolism; D011342:Procainamide / Q000494:pharmacology; D011802:Quinidine / Q000494:pharmacology; D011812:Quinuclidines / Q000494:pharmacology
D000889:Anti-Arrhythmia Agents; D011812:Quinuclidines; D011802:Quinidine; D011342:Procainamide; D011188:Potassium
Osobennosti deĭstviia nekotorykh antiaritmicheskikh veshchestv na ionnye toki v predserdii liagushki.