GLC determination of trihexyphenidyl hydrochloride dosage forms.
A rapid, sensitive, and specific GLC method for the quantitation of trihexyphenidyl hydrochloride in various pharmaceutical dosage forms is described. The procedure involves chloroform extraction of the active ingredient from a weakly acidic solution, followed by GLC determination using a 3% methyl silicone column. The specificity of the system in relation to several compendial drug analogs also is reported.
D002214:Capsules / Q000032:analysis; D002849:Chromatography, Gas; D003692:Delayed-Action Preparations; D008722:Methods; D012996:Solutions / Q000032:analysis; D013607:Tablets / Q000032:analysis; D014282:Trihexyphenidyl / Q000032:analysis*
D002214:Capsules; D003692:Delayed-Action Preparations; D012996:Solutions; D013607:Tablets; D014282:Trihexyphenidyl