Protein binding properties of prazosin.
The serum protein binding proerties of prazosin were determined by the equilibrium dialysis technique, using radiolabeled drug of high specific activity. At concentrations typically found in human therapy, prazosin is bound to serum proteins to the extent of approximately 92 percent. This value is not altered in the presence of several other drugs frequently diminished in conjunction with prazosin.
D001798:Blood Proteins / Q000378:metabolism; D002747:Chlorpropamide / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D011224:Prazosin / Q000097:blood*; D011485:Protein Binding / Q000187:drug effects; D011799:Quinazolines / Q000097:blood*
D001798:Blood Proteins; D011799:Quinazolines; D002747:Chlorpropamide; D011224:Prazosin