[Cell viability after cryodestruction of the tumor].
By histoautoradiography DNA was determined in the Heren carcinoma cells during the first 6 days after cryosurgery of the tumor. During 2.5 days after cryosurgery no labeled cells in the cryodestructed tissue were detected. The DNA synthesizing cells were revealed in separate portions of some tumors 66 hours and longer following cryosurgery. The absence of labeled cells during 66 hours since the moment of cryoexposure indicates the block of DNA synthesis in cryoresistant tumor cells. It evidences that the cells which remained viable after cryosurgery were the cause of the recurrences observed.
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000378:metabolism / Q000503:physiopathology / Q000601:surgery; D002470:Cell Survival; D003452:Cryosurgery; D004273:DNA, Neoplasm / Q000096:biosynthesis; D008297:Male; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000378:metabolism / Q000503:physiopathology / Q000601:surgery*; D051381:Rats; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors
D004273:DNA, Neoplasm; D013936:Thymidine
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