A histological study of idiopathic avascular necrosis of the head of the femur.
We have studied the histological appearances of forty femoral heads with idiopathic avascular necrosis. The characteristic histopathological changes of recurrent necrosis were present in 83 per cent. Recurrent necrosis occurred widely after revascularisation had progressed as far as the subchondral zone. The aetiology of idiopathic avascular necrosis of the femoral head may be a chronic condition which produces repeated infarction. The deformation and incomplete revascularisation of the femoral head may be due to repeated episodes of infarction as well as to mechanical factors related to weight-bearing.
D000293:Adolescent; D005260:Female; D005270:Femur Head / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology*; D005271:Femur Head Necrosis / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D011859:Radiography; D012008:Recurrence