title: The involvement of serotonin in induced ovulation in the immature rat.
abstract: In pregnant mare's serum gonadotropin (PMS) treated immature rats the cortex, cerebellum, caudate nucleus and hypothalamus were isolated and analyzed for their serotonin (5-HT) content at 6-h intervals for 72 h. Results showed a general trend of significant variation occurring in days 1 and 3 after PMS injection with no major variations observed on the second day. The results obtained suggest a possible involvement of 5-HT in the control of ovulation.
mesh_terms: D000818:Animals; D002421:Caudate Nucleus / Q000378:metabolism; D002531:Cerebellum / Q000378:metabolism; D002540:Cerebral Cortex / Q000378:metabolism; D005260:Female; D006064:Gonadotropins, Equine / Q000494:pharmacology; D007031:Hypothalamus / Q000378:metabolism; D010060:Ovulation / Q000187:drug effects; D051381:Rats; D012701:Serotonin / Q000378:metabolism / Q000502:physiology*; D013997:Time Factors
chemical_list: D006064:Gonadotropins, Equine; D012701:Serotonin