Effect of sex on the strain differences in hepatic metabolism of starved and nonstarved rats.
The hepatic metabolism of starved and nonstarved male and female rats from the Wistar and BHE (line 4) strains has been studied. Liver tissue was frozen between precooled copper plates and the levels of various metabolites of the glycolytic and citric acid cycle and adenine nucleotides determined. While the major differences in hepatic metabolism were attributable to the strain of animal, sex effects were also observed. These results suggest that differences in compartmental phosphorylation states may be indicative of a greater lipogenic capacity of these rats compared to normal rats.
D000818:Animals; D003600:Cytosol / Q000378:metabolism; D005260:Female; D008055:Lipids / Q000096:biosynthesis; D008099:Liver / Q000378:metabolism*; D008297:Male; D008930:Mitochondria, Liver / Q000378:metabolism; D010084:Oxidation-Reduction; D010085:Oxidative Phosphorylation; D051381:Rats; D012737:Sex Factors; D013045:Species Specificity; D013217:Starvation / Q000378:metabolism*
D008055:Lipids