[Formation of broad-spectrum antibiotics by cultures of the genus Micromonospora].
Data on the study of antibiotic production by the representatives of Micromonospora and the use of ion exchange resins for intensification of screening antibiotic-producing organisms among Micromonospora are presented. It was found that out of 172 strains of Micromonospora tested 92 (53.5 per cent) cultures produced antibiotics, 18 of which were active against gramnegative bacteria. The use of carboxylic ion exchange resins at early microbiological stages of the screening provided an increase in the frequency of finding broad spectrum antibiotics from 10.4 to 19.7 per cent.
D000327:Adsorption; D000617:Aminoglycosides / Q000096:biosynthesis; D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000302:isolation & purification; D003470:Culture Media; D007475:Ion Exchange Resins; D008826:Microbial Sensitivity Tests; D008847:Micromonospora / Q000378:metabolism*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D003470:Culture Media; D007475:Ion Exchange Resins
Obrazovanie antibiotikov shirokogo spektra deĭstviia kul'turami iz roda Micromonospora.