Clinical evaluation of thyroid imaging with 201T1-chloride.
Clinical value and limitation of thyroid imaging with 201T1Cl were studied. The positive rate of 201T1 was 82% in 22 malignant thyroid lesions and 46% in 37 benign lesions. A 201T1 positive image was obtained when a lesion was parenchymatous and a 201T1 negative one when it was cystic, filled with colloid or hyaline and had massive necrosis or bleeding. Thus 201T1Cl localized in a parenchymatous lesion and did not in a nonparenchymatous one regardless of a malignant or benign disease. An increasing positive lesion in contrast with the surrounding thyroid tissue implies that it may be malignant and a decreasing one benign as a results of review of serial scintiphotos. Scintigraphic methods with 131I and 201T1 are complementary each other and a 201T1 negative image itself has a high diagnostic value but it seems to be better to attach much value to the finding of imaging with 131I when a 201T1 positive image is obtained.
D000328:Adult; D000368:Aged; D002712:Chlorides; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013793:Thallium; D013959:Thyroid Diseases / Q000000981:diagnostic imaging; D013961:Thyroid Gland / Q000000981:diagnostic imaging*
D002712:Chlorides; D007457:Iodine Radioisotopes; D011868:Radioisotopes; D013793:Thallium