title: Receptor binding studies on A1-(2-nitro-4-trimethylammoniophenyl)insulin.
abstract: The results are presented from receptor binding studies and isolated fat cell assays on A1-(2-nitro-4-trimethylammoniophenyl)insulin. In the former tests, the derivative is shown to have properties similar to native insulin and the fat cell assays afford a value of 76 +/- 4%. The importance of a charged, hydrophilic moiety attached at A1-glycine is discussed in the light of the above findings.
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D000818:Animals; D001667:Binding, Competitive; D001681:Biological Assay; D007328:Insulin / Q000031:analogs & derivatives* / Q000378:metabolism; D007700:Kinetics; D051379:Mice; D011972:Receptor, Insulin / Q000378:metabolism*
chemical_list: D007328:Insulin; D011972:Receptor, Insulin