The effects of stomach loads of hypertonic NaCl on thyroidectomized prepubescent rats.
Prepubescent male and female rats (N = 56) were surgically thyroidectomized and given stomach loads of .9% or 6.0% NaCl. The 6.0% NaCl, thyroidectomized S s responded by decreasing food intake and losing weight 24 hours after loading. Normal S s did not, and no sex difference was found. The .9% NaCl thyroidectomized S s drank significantly less than the normals. The results were interpreted in terms of thyroid hormone activity which affects renal function.
D000818:Animals; D001835:Body Weight; D004327:Drinking Behavior / Q000502:physiology*; D005247:Feeding Behavior / Q000502:physiology*; D005260:Female; D008297:Male; D051381:Rats; D012462:Saline Solution, Hypertonic / Q000494:pharmacology*; D012965:Sodium Chloride / Q000494:pharmacology*; D013961:Thyroid Gland / Q000502:physiology*; D014882:Water-Electrolyte Balance
D012462:Saline Solution, Hypertonic; D012965:Sodium Chloride