title: Experimental tinea versicolor in rabbits and humans with Pityrosporum orbiculare.
abstract: The purpose of this investigation was to produce experimental tinea versicolor in rabbits and humans with Pityrosporum orbiculare. Inoculation with P. orbiculare under plastic occlusion on the glabrous follicle-rich inside of the rabbit ear resulted in a tinea versicolor-like lesion after 1 week in 3 of 4 animals. One week after inoculation with P. orbiculare under plastic occlusion, experimental infections similar to those found clinically in tinea versicolor were seen in 10 of 12 patients with a history of tinea versicolor and in 3 of 6 normal volunteers. It was not possible to produce experimental infections without occlusion. Spontaneous healing usually occurred.
mesh_terms: D000818:Animals; D006801:Humans; D008290:Malassezia / Q000472:pathogenicity*; D011817:Rabbits; D012867:Skin / Q000473:pathology; D014010:Tinea Versicolor / Q000473:pathology