Effects of hypothalamic injections of 5,6-dihydroxytryptamine on thermoregulation in rats.
5,6-Dihydroxytryptamine, a serotonin depletor, infused directly into the anterior hypothalamus of rat's brain, produced an increase in both heat production and heat loss (as indicated by changes in peripheral circulation) at temperatures of 8, 15 and 22 degrees C. The rectal temperature of these treated rats remained constant.
D015115:5,6-Dihydroxytryptamine / Q000494:pharmacology*; D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D001833:Body Temperature Regulation / Q000187:drug effects*; D007031:Hypothalamus / Q000187:drug effects*; D007032:Hypothalamus, Anterior / Q000187:drug effects*; D008297:Male; D051381:Rats; D012881:Skin Temperature / Q000187:drug effects
D015115:5,6-Dihydroxytryptamine