Effects of thyroidectomy on monoamine oxidase activities toward tyramine and serotonin in the circumventricular nuclei of the rat.
Following thyroidectomy, monoamine oxidase (MAO) activities toward tyramine decreased significantly by 20% in the nucleus periventricularis and the nucleus arcuatus among the 3 hypothalamic nuclei of the rat, while MAO activity toward serotonin decreased significantly by 10% only in the nucleus periventricularis. It is suggested that thyroidectomy induced selective changes on the multiple forms of MAO in the discrete circumventricular nuclei.
D000818:Animals; D007031:Hypothalamus / Q000201:enzymology*; D007033:Hypothalamus, Middle / Q000201:enzymology*; D008297:Male; D008995:Monoamine Oxidase / Q000378:metabolism*; D051381:Rats; D012701:Serotonin / Q000378:metabolism*; D013961:Thyroid Gland / Q000502:physiology*; D013965:Thyroidectomy; D014439:Tyramine / Q000378:metabolism*
D012701:Serotonin; D008995:Monoamine Oxidase; D014439:Tyramine