[Coumarin-induced fetal abnormalities and stippled epiphyses].
The ability of most anticoagulants (except heparin) to cross the placenta and the consequent hemorrhage in the fetus has been recognized for some time (3). A teratogenic effect specifically attributed to warfarin sodium is a more recent finding (7, 9, 10). The following is a case report of a newborn with clinical and roentgenographic features similar to the cases reported previously.
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000015:Abnormalities, Multiple / Q000139:chemically induced; D000074:Acenocoumarol / Q000009:adverse effects*; D000328:Adult; D002806:Chondrodysplasia Punctata / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D011247:Pregnancy
D000074:Acenocoumarol
Embryo-foetopathie coumarinique et maladie des épiphyses ponctuees.