[Humoral factors in the regulation of the natural resistance of the body in toxic lesion of the liver].
The dynamics of natural resistance factors (complement, lysozyme, the bactericidal potency of blood serum) were found to be similar in rabbits with the toxic lesions of the liver resulting from the administration of carbon tetrachloride and in intact homologous rescipients receiving the serum of poisoned animals. Simultaneously a decrease in the complement titre and an increase in lysozyme activity and in the bactericidal potency of blood serum were observed. The effect thus revealed could be suppressed by treating the serum with contrical, a polyvalent proteinase inhibitor.
D000818:Animals; D001770:Blood Bactericidal Activity / Q000187:drug effects; D002252:Carbon Tetrachloride Poisoning / Q000276:immunology; D056486:Chemical and Drug Induced Liver Injury / Q000276:immunology*; D003165:Complement System Proteins / Q000032:analysis; D007109:Immunity / Q000187:drug effects; D007113:Immunity, Innate / Q000187:drug effects*; D008239:Lysine / Q000097:blood; D009113:Muramidase / Q000097:blood; D011817:Rabbits; D013997:Time Factors
D003165:Complement System Proteins; D009113:Muramidase; D008239:Lysine
Gumoral'nye faktory reguliatsii estestvennoĭ rezistentnosti organizma pri toksicheskom porazhenii pecheni.