[Effect of anabolic steroid hormones on protein and lipid metabolic indices in thermal injury].
Burns of 20% of rat skin caused a decrease in content of albumins and gamma-globulins in blood and simultaneous increase in content of alpha 1- and alpha 2-globulins. Content C17 : 1 and C19 : 1 monoenoic fatty acids was decreased in blood and liver tissue of the rats with burns. These patterns were normalized after administration into the animals of synthetic anabolic steroid nerobolyl at a dose 5 mg/kg. Burning castrated male rats led to a decrease in concentration of albumins, alpha 1- and alpha 2-globulins in blood with simultaneous increase of monoenoic fatty acids in blood and liver tissue. Nerobolyl normalized these patterns at a dose 20 mg/kg, while a dose 5 mg/kg was distinctly less effective.
D045930:Anabolic Agents / Q000627:therapeutic use*; D000818:Animals; D001798:Blood Proteins / Q000378:metabolism*; D002056:Burns / Q000097:blood* / Q000188:drug therapy; D002369:Castration; D004353:Drug Evaluation, Preclinical; D005227:Fatty Acids / Q000097:blood; D008055:Lipids / Q000097:blood*; D008099:Liver / Q000378:metabolism; D008297:Male; D009277:Nandrolone / Q000031:analogs & derivatives; D010666:Phenylpropionates / Q000008:administration & dosage; D051381:Rats
D045930:Anabolic Agents; D001798:Blood Proteins; D005227:Fatty Acids; D008055:Lipids; D010666:Phenylpropionates; D009277:Nandrolone
Vliianie anabolicheskikh steroidnykh gormonov na pokazateli belkovogo i lipidnogo obmena pri termicheskoĭ travme.