[Resistance of BCG-vaccinated body to tumor growth after administration of cyclophosphamide and desensitization].
It was shown that tumor growth is intensifying as a result of tumor cell implantation not only in early sensitization of BCG-vaccinated organism (see previously published data) but at the later period as well. Cyclophosphan removed this effect whereas desensitization carried out against the background of cyclophosphan action restored it. The data on the relationship between tuberculin allergy and the state of immunological defence reactions of the body suggest the possibility of stimulation of tumor growth as well as of its inhibition.
D000818:Animals; D001500:BCG Vaccine / Q000276:immunology*; D002279:Carcinoma 256, Walker / Q000276:immunology* / Q000473:pathology; D003520:Cyclophosphamide / Q000276:immunology*; D003888:Desensitization, Immunologic; D006968:Hypersensitivity, Delayed / Q000276:immunology; D008297:Male; D051381:Rats; D014373:Tuberculin / Q000276:immunology
D001500:BCG Vaccine; D014373:Tuberculin; D003520:Cyclophosphamide
Soprotivliaemost' vaktsinirovannogo BTsZh organizma rostu opukholi posle primeneniia tsiklofosfana i desensibilizatsii.