title: [Proposal for a method of testing the acute irritative effect of substances by experiments upon animals (author's transl)].
abstract: This paper deals with the test methods for the irritative effect of substances, and suggests a method for standardised determination of acute dermal I.D.50. Liquids or easily soluble substances can be checked in various concentrations with the help of an open application on rabbits.
mesh_terms: D004655:Emulsions; D006801:Humans; D007509:Irritants / Q000494:pharmacology; D012867:Skin / Q000187:drug effects*; D012882:Skin Tests; D012996:Solutions
chemical_list: D004655:Emulsions; D007509:Irritants; D012996:Solutions
vernacular_title: Vorschlag einer Methode zur Prüfung der akuten irritativen Wirkung von Substanzen im Tierversuch.