Cytogenetic properties of Chinese hamster V79-E cells: G-banding, C-banding, nucleolar organizer regions, and sister chromatid exchanges.
A line of the Chinese hamster V79 strain, denominated as V79-E, is cytogenetically characterized. It has a modal chromosome number of 22. Chromosome morphology, G- and C-banding reveal strong differences from the normal complement of the Chinese hamster presumably caused by rearrangements of chromosome segments during the past 20 years of in vitro culture. 4 chromosomes possess terminal nucleolar organizer regions. Spontaneous sister chromatid exchanges occur with a frequency of 0.38 sister chromatid exchanges per chromosome.
D000818:Animals; D002460:Cell Line; D002466:Cell Nucleolus; D002842:Chromatids; D002871:Chromosome Banding; D002875:Chromosomes / Q000032:analysis*; D006224:Cricetinae; D003412:Cricetulus; D007621:Karyotyping; D008168:Lung; D014178:Translocation, Genetic