Interaction of kanamycin and noise exposure.
The amount of hair cell damage in the cochleas of guinea pigs after exposure to different experimental conditions suggests that a 'safe' level of kanamycin has a potentiating effect on damage due to noise. Such an effect lasts more than 20 days after the cessation of the drug administration.
D000818:Animals; D003051:Cochlea / Q000187:drug effects*; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000187:drug effects; D007612:Kanamycin / Q000633:toxicity*; D009622:Noise / Q000009:adverse effects*; D013997:Time Factors
D007612:Kanamycin