Tissue perfusion rate determined from the decay of oxygen-15 activity after photon activation in situ.
Rates of cerebral perfusion were obtained from measurements of the disappearance (wash-out) of oxygen-15 after in situ tissue activation with 45-million-volt x-rays. In an anesthetized cat, typical values were 90 milliliters per minute per 100 grams of tissue, with 55 percent wash-out. In a specific radiotherapy patient, the value was 65 milliliters per minute per 100 grams of tissue, with 63 percent wash-out of oxygen-15 through incorporation into tissue water.
D000818:Animals; D001921:Brain / Q000098:blood supply*; D002415:Cats; D006801:Humans; D009369:Neoplasms / Q000098:blood supply; D010100:Oxygen / Q000097:blood* / Q000528:radiation effects; D010104:Oxygen Radioisotopes; D012039:Regional Blood Flow; D014965:X-Rays
D010104:Oxygen Radioisotopes; D010100:Oxygen