[Modeling the oxidative detoxication function of the liver using electrochemical oxidation reactions].
An electrochemical system is developed, which permits to simulate oxidative reactions, processing in presence of cytochrome P-450. The system, combined with a dialyzing apparatus, may be used for oxidation and elimination of various hydrophobic substances of exoand endogenous origin from animal and human organisms.
D000632:Aminopyrine / Q000378:metabolism; D000814:Aniline Compounds / Q000378:metabolism; D000818:Animals; D001663:Bilirubin / Q000378:metabolism; D001711:Biotransformation; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003956:Dialysis; D004563:Electrochemistry; D008099:Liver / Q000201:enzymology*; D008954:Models, Biological; D009596:Nitrophenols / Q000378:metabolism; D010084:Oxidation-Reduction
D000814:Aniline Compounds; D009596:Nitrophenols; D000632:Aminopyrine; D003577:Cytochrome P-450 Enzyme System; D001663:Bilirubin
Modelirovanie okislitel'noĭ detoksitsiruiushcheĭ funktsii pecheni s pomoshch'iu reaktsiĭ élektrokhimicheskogo okisleniia.