title: [Nonachlazine in solution as an arresting agent in stenocardiac attacks].
abstract: Nonachlazine infused in the form of a solution penetrates rapidly the blood and organs. In experiments on cats it was shown that infusion of the drug into the stomach enriches the speed of blood flow and oxyhemoglobin amount in the coronary sinus blood after 2--3 minutes. Heart oxygen consumption increases slightly. Nonachlazine solution is little toxic. As a result of pharmacological research it is recommended for removing angina pectoris attacks in patients irresponsive to nitroglycerin.
mesh_terms: D000787:Angina Pectoris / Q000188:drug therapy*; D000818:Animals; D002415:Cats; D003326:Coronary Circulation / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D009628:Nonachlazine / Q000378:metabolism / Q000627:therapeutic use* / Q000633:toxicity; D010640:Phenothiazines / Q000627:therapeutic use*; D051381:Rats; D012996:Solutions; D013997:Time Factors; D014018:Tissue Distribution
chemical_list: D010640:Phenothiazines; D012996:Solutions; D009628:Nonachlazine
vernacular_title: Nonakhlazin v rastvore kak sredstvo kupirovaniia pristupov stenokardii.