title: [Papillomatosis of the opening of the major duodenal papilla in chronic, recurrent pancreatitis (based on surgical biopsy data)].
abstract: Examinations of 55 major duodenal papillas (MDP) amputated in patients with chronic relapsing pancreatitis revealed papillomatosis of the opening zone in 20 (36%). Papillomatosis developed when the pancreating and bile ducts discharged into the duodenum separately at the top of MDP without forming an ampoule. Papillomatosis was manifested by fibrous-epithelial papillar hyperplastic outgrowths representing pathologically altered folds of the MDP mucous membrane. The features of changes in papillary outgrowths were shown to include circulatory disorders, lympho-plasmocytic infiltration of the stroma, adenomatosis, etc. The causes of papillomatosis development and its association with chronic relapsing pancreatitis are discussed.
mesh_terms: D014670:Ampulla of Vater / Q000473:pathology*; D001650:Bile Duct Neoplasms / Q000209:etiology / Q000473:pathology*; D001706:Biopsy; D002908:Chronic Disease; D006801:Humans; D009092:Mucous Membrane / Q000473:pathology; D010195:Pancreatitis / Q000150:complications*; D010212:Papilloma / Q000209:etiology / Q000473:pathology*; D012008:Recurrence
vernacular_title: Papillomatoz ust'ia bol'shogo duodenal'nogo sosochka u bol'nykh khronicheskim retsidiviruiushchim pankreatitom (po dannym operatsionnykh biopsiĭ).