title: [Topography and the protein synthesis level in the large pyramidal neurons during sleep and wakefulness].
abstract: In the large pyramidal neurons of the pariental cortex of cat during the slow-waved phase of sleep in comparison to the state of awake, an uneven decrease of the level of 3H-leucine inclusion was established in  different functionally specialized zones of the cell. Using electron microscopy, a decrease in the number of polysomes and membrane-attached ribosomes was shown in the perinuclear zone of large pyramids in slow-waved phase of sleep. The results obtained suggest a decrease in the intensity of protein synthesis in comparison to the state of awake.
mesh_terms: D000818:Animals; D001345:Autoradiography; D002415:Cats; D005260:Female; D007930:Leucine / Q000378:metabolism; D008297:Male; D008854:Microscopy, Electron; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D009474:Neurons / Q000378:metabolism* / Q000648:ultrastructure; D010296:Parietal Lobe / Q000502:physiology; D012270:Ribosomes / Q000648:ultrastructure; D012890:Sleep / Q000502:physiology*; D012894:Sleep Stages / Q000502:physiology; D014851:Wakefulness / Q000502:physiology*
chemical_list: D009419:Nerve Tissue Proteins; D007930:Leucine
vernacular_title: Izuchenie topografii i urovnia sinteza belka v krupnykh piramidnykh neĭronakh vo vremia sna i bodrstvovaniia.