Direct evidence favouring the notion that erythropoietin alters iron transport across the isolated intestinal tract of the rat.
A simple and reproducible method, using the isolated not everted intestine of the rat, for the study of iron transport is presented. Erythropoietin (ESF) enhanced significantly the passage of 59Fe across the intestine augmenting its movement at mucosal and serosal layers of the intestinal well.
D000818:Animals; D004921:Erythropoietin / Q000494:pharmacology*; D066298:In Vitro Techniques; D007408:Intestinal Absorption / Q000187:drug effects*; D007501:Iron / Q000378:metabolism*; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D051381:Rats; D013997:Time Factors
D004921:Erythropoietin; D007501:Iron