title: Role of prolactin the the expression of casein genes in the virgin rabbit.
abstract: Prolactin was injected into mature virgin rabbits. Casein mRNA, already present prior to the treatment was enhanced by prolactin. This accumulation of casein mRNA was not accompanied by a parallel significant synthesis of casein. Th effect of prolactin took place without a previous cellular multiplication. The mammary cell is therefore sensitive to prolactin before the first pregnancy but prolactin then displays only an abortive effect on the expression of casein genes.
mesh_terms: D000818:Animals; D002364:Caseins / Q000235:genetics*; D005260:Female; D005796:Genes / Q000187:drug effects*; D007700:Kinetics; D011388:Prolactin / Q000494:pharmacology*; D012333:RNA, Messenger / Q000235:genetics; D011817:Rabbits; D014158:Transcription, Genetic / Q000187:drug effects*
chemical_list: D002364:Caseins; D012333:RNA, Messenger; D011388:Prolactin