title: [Treatment of osteoporosis with a new retard-preparation of sodium fluoride (author's transl)].
abstract: 25 female patients with different forms of osteoporosis (progredient form in elderly patients, steroid osteoporosis, involutive osteoporosis) treated during a period varying between 1 to 24 months with a new compound preparation containing 25 mg sodium fluoride and 200 mg L-ascorbic acid per tablet. The daily dose amounts to 2 tablets. Clinical success was observed in 18 patients, X-ray controls showed increase of bone density in 8 patients. In 3 cases it was necessary to discontinue treatment because of side effects (2 patients with pains in the bones and joints, 1 patient with stomach troubles). Late side effects have not been observed. At present the treatment of certain forms of osteoporosis with sodium fluoride is the only effective therapy of this disease.
mesh_terms: D000368:Aged; D003692:Delayed-Action Preparations; D005260:Female; D005459:Fluorides / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010024:Osteoporosis / Q000188:drug therapy*; D011859:Radiography; D012969:Sodium Fluoride / Q000627:therapeutic use*; D013131:Spine / Q000000981:diagnostic imaging
chemical_list: D003692:Delayed-Action Preparations; D012969:Sodium Fluoride; D005459:Fluorides
vernacular_title: Therapie der Osteoporose mit einem neuen Natriumfluorid-Retardopräparat.