title: Sex-linked inheritance of cleft palate.
abstract: A family pedigree is reported in which males in four generations are affected with midline isolated cleft palate. This is the second report of cleft palate inherited as a sex-linked recessive trait, and it emphasizes the importance of careful pedigree construction when counseling families of children afflicted with this disorder.
mesh_terms: D000328:Adult; D002675:Child, Preschool; D002972:Cleft Palate / Q000235:genetics*; D005260:Female; D005808:Genes, Recessive; D005817:Genetic Counseling; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D010375:Pedigree; D012730:Sex Chromosomes; D014960:X Chromosome