title: Wikstromol, antitumor lignan from Wikstroemia foetida var. oahuensis Gray and Wikstroemia uva-ursi Gray (Thymelaeaceae).
abstract: The ethanol extracts of Wikstroemia foetida var. oahuensis and Wikstroemia uva-ursi showed antitumor activity against the P-388 lymphocytic leukemia (3PS) test system One PS-active constituent of both plants was the lignan wikstromol. Several inactive compounds were identified as daphnoretin, pinoresinol, and syringaresinol.
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000627:therapeutic use; D055598:Chemical Phenomena; D002621:Chemistry; D005663:Furans / Q000302:isolation & purification* / Q000627:therapeutic use; D007942:Leukemia, Experimental / Q000188:drug therapy; D017705:Lignans
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D005663:Furans; D017705:Lignans; C020436:nortrachelogenin