title: Pure red cell hypoplasia associated with long-arm deletion of chromosome 5.
abstract: A further instance of the new hematologic entity of pure red cell hypoplasia with deletion of the the long arm of a chromosome 5(5q-) was seen in a 59-year-old white male. Examination of the bone marrow showed depressed erythroid cells with normal granulocytic and megakaryocytic precursors. Chromosomal analysis showed deletion of a chromosome 5 without any apparent translocation. This karyotype may be associated with acute leukemia.
mesh_terms: D000741:Anemia, Aplastic / Q000097:blood / Q000235:genetics* / Q000628:therapy; D001803:Blood Transfusion; D002872:Chromosome Deletion; D002905:Chromosomes, Human, 4-5; D004913:Erythrocytes, Abnormal; D006801:Humans; D008297:Male; D008875:Middle Aged