title: Invasive cancer of the cervix after cryosurgery. Pitfalls of conservative management.
abstract: Eight cases of invasive cervical carcinoma detected after cryotherapy for presumably noninvasive cervical lesions are reported. Three of these patients died from their disease less than 2 years following definitive therapy. The potential dangers of a less-than-optimal work-up of patients prior to freezing are analyzed and discussed in detail. Possible explanations for failures of cryotherapy are discussed, and guidelines for prevention of failures are presented.
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D003127:Colposcopy; D003452:Cryosurgery; D005188:False Negative Reactions; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D014626:Vaginal Smears