[Change in the antinociceptive effect occurring in stimulation of the rat midbrain under the influence of morphine].
In chronic experiments on rats it was established that electric stimulation of certain areas of the midbrain depresses pain reactions of different genesis. Morphine in subanalgetic doses (2--2.5 mg/kg) reveals and potentiates the antinociceptive effect of central stimulation shown first of all by depression of the complex highly integrated components of an emotionally behavioral conductive reaction to pain.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D008636:Mesencephalon / Q000187:drug effects* / Q000502:physiology; D009020:Morphine / Q000494:pharmacology*; D009619:Nociceptors / Q000187:drug effects* / Q000502:physiology; D010146:Pain / Q000503:physiopathology; D051381:Rats; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology; D013268:Stimulation, Chemical
D009020:Morphine
Izmenenie pod vliianiem morfina antinotsitseptivnogo éffekta, voznikaiushchego pri stimuliatsii srednego mozga krysy.