title: The effects of temperature variations on cryoprecipitate.
abstract: The effect of temperature on Factor VIII levels in blood and cryoprecipitate was assessed. Freshw collected units of blood required several hours to reach 4 C, but this delay seemed of little importance since equal amounts of cryoprecipitated Factor VIII were recovered from blood stored either at 22 C or at 4 C. Freezing at -80, -60, or -40 C produced identical yields of Factor VIII, whereas freezing at -20 C resulted in significantly lower recoveries. This might be expected if one considers the physiochemical changes that occur during the freezing process.
mesh_terms: D001793:Blood Preservation; D003080:Cold Temperature; D005167:Factor VII / Q000302:isolation & purification*; D005615:Freezing; D006801:Humans
chemical_list: D005167:Factor VII