Mortality in lupus nephritis.
The principal causes of death of 68 patients with lupus glomerulonephritis were reviewed. Renal failure (40%), vascular events (25%), and infections (16%) were the predominant causes. Diffuse proliferative glomerulonephritis was associated with an increased frequency of renal failure. A bimodal pattern of early deaths due to active lupus and sepsis and late deaths from vascular events was found superimposed on a constant rate of death from renal failure.
D058186:Acute Kidney Injury / Q000401:mortality; D000328:Adult; D001424:Bacterial Infections / Q000401:mortality; D002493:Central Nervous System Diseases / Q000401:mortality; D002561:Cerebrovascular Disorders / Q000401:mortality; D003645:Death, Sudden / Q000209:etiology; D005921:Glomerulonephritis / Q000401:mortality; D006333:Heart Failure / Q000401:mortality; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008107:Liver Diseases / Q000401:mortality; D008180:Lupus Erythematosus, Systemic / Q000401:mortality*; D008396:Maryland; D008875:Middle Aged; D009393:Nephritis / Q000401:mortality*; D011655:Pulmonary Embolism / Q000401:mortality; D013997:Time Factors