title: First observations on treatment of cholesteatoma with (N-acetyl)cysteine.
abstract: In a series of cholesteatoma patients the benefit of local application of acetylcysteine was demonstrated. Chemical studies and fractional analyses were used to reveal the breakdown of keratin. Histochemically the influence of acetylcysteine on keratin is confirmed.
mesh_terms: D000111:Acetylcysteine / Q000627:therapeutic use*; D000287:Administration, Topical; D002781:Cholesteatoma / Q000188:drug therapy*; D004427:Ear Diseases / Q000188:drug therapy*; D006801:Humans; D007633:Keratins / Q000378:metabolism
chemical_list: D007633:Keratins; D000111:Acetylcysteine