The histology of myocardium in malignant hyperthermia: a preliminary report of 11 cases.
The preliminary results of a retrospective examination of the myocardium from 11 patients who responded to general anaesthesia with malignant hyperthermia are presented. Light-microscopical examination of the sections revealed no specific changes due to malignant hyperthermia. Contraction bands were demonstrated in 4 cases and it is concluded that the present investigation does not support the suggestion that a specific myofibrillar damage is responsbile for the arrhythmias seen in malignant hyperthermia.
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008305:Malignant Hyperthermia / Q000473:pathology*; D008875:Middle Aged; D009200:Myocardial Contraction; D009206:Myocardium / Q000473:pathology*; D012189:Retrospective Studies