Acute and subchronic kidney injuries in mice induced by diphenylamine (DPA).
Adult and female mice were fed with diphenylamine by oral gavage. Mice of both sexes showed up with kidney injuries involving tubuli and some glomeruli. RE-cells in livers of both sexes were activated with content of yellowish-brown pigment.
D000208:Acute Disease; D000814:Aniline Compounds / Q000506:poisoning*; D000818:Animals; D004159:Diphenylamine / Q000506:poisoning*; D005260:Female; D007674:Kidney Diseases / Q000139:chemically induced* / Q000473:pathology; D007678:Kidney Glomerulus / Q000473:pathology; D007684:Kidney Tubules / Q000473:pathology; D008099:Liver / Q000187:drug effects; D008297:Male; D051379:Mice; D012157:Mononuclear Phagocyte System / Q000187:drug effects
D000814:Aniline Compounds; D004159:Diphenylamine