[Effect of hyaluronidase on morphological changes in the myocardium in experimental myocardial infarct].
ECG, histological, and histochemical examinations on a model of experimental myocardial infarction showed that hyaluronidase administration leads to a decrease in the sum of elevation of the ST segment and the number of points (NST) at which this elevation is recorded, acceleration of healing processes in the affected zone, and to activation of respiratory enzymes and the pentosophosphate shunt in some of the fibres of the peri-infarction zone.
D000818:Animals; D004341:Drug Evaluation; D004950:Esterases / Q000378:metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006321:Heart / Q000187:drug effects*; D006651:Histocytochemistry; D006821:Hyaluronoglucosaminidase / Q000627:therapeutic use*; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000473:pathology; D009206:Myocardium / Q000201:enzymology / Q000473:pathology*; D011817:Rabbits; D013385:Succinate Dehydrogenase / Q000378:metabolism
D005954:Glucosephosphate Dehydrogenase; D013385:Succinate Dehydrogenase; D004950:Esterases; D006821:Hyaluronoglucosaminidase
Vliianie gialuronidazy na morfologicheskie izmeneniia v miokarde pri eksperimental'nom infarkte.