Effect of alkoxyglycerols on the frequency of fistulas following radiation therapy for carcinoma of the uterine cervix.
The incidence of injuries following radiation therapy for carcinoma of the uterine cervix is markedly decreased by the administration of alkoxyglycerols. This is the case for less harmful injuries as well as for the more severe ones, i.e. the fistulas. Recto-vaginal and vesico-vaginal fistulas are reduced with 47 per cent when alkoxyglycerols are administered prior to radiation treatment.
D005260:Female; D005990:Glycerol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D011832:Radiation Injuries / Q000517:prevention & control*; D011878:Radiotherapy / Q000009:adverse effects*; D012006:Rectovaginal Fistula / Q000209:etiology / Q000517:prevention & control*; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*; D014719:Vesicovaginal Fistula / Q000209:etiology / Q000517:prevention & control*
D005990:Glycerol