[Course of acute myocardial ischemia in dogs depending on the pharmacological background].
In acute myocardial ischemia of dogs glycogen is mobilized most completely and its break down products are utilized most efficaciously after administration of izatin rather than after gamma-hydroxybutyric acid (GABA) and guthymin. Izatin potentiates a beneficial effect of GABA on myocardial energy efficiency.
D000818:Animals; D003327:Coronary Disease / Q000188:drug therapy / Q000378:metabolism*; D004285:Dogs; D004734:Energy Metabolism / Q000187:drug effects; D005993:Glycerolphosphate Dehydrogenase / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism; D006164:Guanylthiourea / Q000627:therapeutic use*; D007211:Indoles / Q000627:therapeutic use*; D007510:Isatin / Q000627:therapeutic use*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D009252:NADPH Dehydrogenase / Q000378:metabolism; D010762:Phosphorylase a / Q000378:metabolism; D010763:Phosphorylase b / Q000378:metabolism; D013385:Succinate Dehydrogenase / Q000378:metabolism; D013890:Thiourea / Q000031:analogs & derivatives*; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use*
D007211:Indoles; D005680:gamma-Aminobutyric Acid; D007510:Isatin; D006003:Glycogen; D005993:Glycerolphosphate Dehydrogenase; D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase; D009252:NADPH Dehydrogenase; D010762:Phosphorylase a; D010763:Phosphorylase b; D013890:Thiourea; D006164:Guanylthiourea
Techenie ostroĭ ishemii miokarda sobak v zavisimosti ot farmakologicheskogo fona.