title: Effect of ethanol on levels of isoniazid, sulfanilamide and sulfapyridin in mouse blood.
abstract: The effect of ethanol of blood levels of free and conjugated sulfonamides (sulfanilamide and sulfapyridin) and isoniazid was investigated in mice. Ethanol (1.5 and 4 mg/g i.v.) enhanced the amount of conjugated isoniazid without affecting the total amount of isoniazid in blood, and tended to raise the total amount of the sulfonamides.
mesh_terms: D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D007538:Isoniazid / Q000097:blood*; D051379:Mice; D013424:Sulfanilamides / Q000097:blood*; D013427:Sulfapyridine / Q000097:blood*
chemical_list: D013424:Sulfanilamides; D000431:Ethanol; D007538:Isoniazid; D013427:Sulfapyridine