[Acute treatment with verapamil of paroxysmal supraventricular tachycardia and atrial flutter in paediatric age (author's transl)].
43 patients, 3 days to 12 years old, presented 68 paroxysms of supraventricular tachycardia and 2 crises of atrial flutter. 6 patients had a WPW syndrome and only 7 had an associated cardiac disease; the remaining had no other complaint but the arrhythmia. Verapamil, administered in the dose of 0.125-0.25 mg/Kg intravenously, interrupted critically the tachycardia in virtually all cases. The flutter was converted to atrial fibrillation with a slower ventricular rate. No adverse effects were observed but in two cases: one had a cardiac arrest promptly relieved and another a ventricular bradycardia corrected by atropine. Both cases had received an overdose of the drugs.
D000367:Age Factors; D001282:Atrial Flutter / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D004562:Electrocardiography; D006323:Heart Arrest / Q000139:chemically induced; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D013614:Tachycardia, Paroxysmal / Q000188:drug therapy*; D014700:Verapamil / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D014700:Verapamil
Trattamento acuto della tachicardia parossistica sopraventricolare e del flutter con verapamil, nell'etá pediatrica.