Seeding of intracranial ependymomas in children.
19 cases of intracranial ependymomas were reviewed to determine the incidence of seeding. 4 patients demonstrated conclusive evidence of seeding in sites remote from the operative and irradiated field, 3 of whom had high-grade ependymomas. Clinical-pathological correlation disclosed a greater tendency to seeding and a worse prognosis among patients with high-grade ependymomas. A more aggressive therapeutic approach is indicated when high-grade ependymomas are involved.
D000293:Adolescent; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D002551:Cerebral Ventricle Neoplasms / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D004806:Ependymoma / Q000473:pathology / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D009366:Neoplasm Seeding