Predicting serum vitamin E concentrations from the age of normal and anticonvulsant drug-treated epileptic children using regression equations.
Serum vitamin E was assayed in 100 patients who were apparently normal, with no medical problems and on no medication, and whose ages ranged from 2 to 12 years. Serum vitamin E was also assayed in 100 patients with grand mal convulsive disorders, on anticonvulsants, but on no other drugs, with no gastrointestinal problems and in a similar age range. In the 100 control children, there was a tendency for serum vitamin E to increase with age. Serum vitamin E concentrations in 100 anticonvulsant drug-treated epileptic children were significantly lower than in the control group and did not increase with age. In the control group, a regression analysis was used to predict serum vitamin E concentrations in different age groups. This information would be useful for population and metabolic studies of serum vitamin E concentrations.
D000367:Age Factors; D000927:Anticonvulsants / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D014810:Vitamin E / Q000097:blood*
D000927:Anticonvulsants; D014810:Vitamin E