title: Chronic mucocutaneous candidiasis. Successful treatment with intermittent oral doses of clotrimazole.
abstract: Treatment of chronic mucocutaneous candidiasis has included drugs, immunotherapy, and replacement of nutritional and endocrine deficiency. Although amphotericin B is the best known and most commonly used form of treatment, the imidazole antibiotic clotrimazole has shown promise as an effective agent that can be given orally with low toxicity. A 9-year-old girl responded to intermittent clotrimazole therapy with complete and prolonged remission. This form of treatment offers advantages in safety and effectiveness over other therapies for chronic mucocutaneous candidiasis.
mesh_terms: D000284:Administration, Oral; D002179:Candidiasis, Cutaneous / Q000188:drug therapy*; D002648:Child; D002908:Chronic Disease; D003022:Clotrimazole / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage*; D009092:Mucous Membrane / Q000187:drug effects
chemical_list: D007093:Imidazoles; D003022:Clotrimazole