title: Antepartum fetal testing. I. The oxytocin challenge test.
abstract: Two hundred seventy-eight high-risk patients were managed by a comprehensive assessment of the anatomic, biochemical, and functional environment of the fetoplacental unit utilizing predetermined guidelines. Decisions to terminate pregnancy were reserved for patients who demonstrated a positive OCT. Perinatal outcome in patients with positive OCT's was significantly worse than in patients who did not have a positive OCT. Patients with suspicious OCT's frequently had positive OCT's and were more likely to bear growth-retarded infants, whereas negative OCT's in general were associated with a favorable outcome. Correlation of estriol excretion with the OCT and perinatal outcome was inconsistent. There were a total of four prenatal deaths, all of which were considered unpreventable.
mesh_terms: D000013:Congenital Abnormalities / Q000150:complications; D005260:Female; D005313:Fetal Death / Q000209:etiology; D005333:Fetus; D006801:Humans; D007751:Labor, Induced; D010121:Oxytocin; D011247:Pregnancy; D012306:Risk; D014590:Uterine Contraction / Q000187:drug effects
chemical_list: D010121:Oxytocin