Trisomy 8p due to the 3:1 segregation of the balanced translocation t(8;15)mat.
An additional small G-like chromosome was found in a newborn female with multiple abnormalities and hemorrhagic diathesis. G banding showed that the index patient was trisomic for the short arm of chromosome 8 and revealed the anomaly t(8;15)(q12;p11) in her mother. The relationship between chromosome 8 and multiple hemorrhages is discussed.
D000015:Abnormalities, Multiple / Q000235:genetics; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002901:Chromosomes, Human, 13-15; D002906:Chromosomes, Human, 6-12 and X; D005167:Factor VII / Q000235:genetics; D005260:Female; D005809:Genes, Regulator; D006474:Hemorrhagic Disorders / Q000235:genetics; D006801:Humans; D007231:Infant, Newborn; D014178:Translocation, Genetic; D014314:Trisomy
D005167:Factor VII