Cholestryl-phosphoryl-choline in lipid bilayers.
Cholesteryl-phosphoryl-choline (CPC), a hybrid between cholesterol and lecithin, is incorporated into sonicated liposomes and erythrocyte membranes similarly to cholesterol. The effect of CPC on lipid microviscosity and degree of order is smaller, but not significantly than that of cholesterol. It is proposed that CPC may be employed as an efficient modulator of lipid dynamics.
D001769:Blood; D002784:Cholesterol / Q000494:pharmacology; D004910:Erythrocyte Membrane / Q000187:drug effects*; D004912:Erythrocytes / Q000187:drug effects*; D006801:Humans; D066298:In Vitro Techniques; D008081:Liposomes; D008567:Membranes, Artificial; D009996:Osmotic Fragility / Q000187:drug effects; D010713:Phosphatidylcholines / Q000494:pharmacology; D013696:Temperature; D014783:Viscosity
D008081:Liposomes; D008567:Membranes, Artificial; D010713:Phosphatidylcholines; D002784:Cholesterol