title: [Effect of polyethylene glycol on association of muscle phosphorylase B].
abstract: It has been shown that a neutral polymer poly(ethyleneglycol) with molecular weight of 4000 and more shifts the equilibrium between the dimer and tetramer forms of phosphorylase B from rabbit skeletal muscles in the direction of formation of species with higher molecular weights. Poly(ethyleneglycol) with molecular weight below 600 has no effect on the association process. Phosphorylase B is precipitated in the form of crystals in the presence of poly(ethyleneglycol) mol. weight 40,000), when the concentration of the latter is higher than 50 mg/ml. AMP and sulfate ions are required for the crystallization process.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D003460:Crystallization; D046911:Macromolecular Substances; D008968:Molecular Conformation; D008970:Molecular Weight; D009132:Muscles / Q000201:enzymology*; D010763:Phosphorylase b; D006005:Phosphorylases; D011092:Polyethylene Glycols
chemical_list: D046911:Macromolecular Substances; D011092:Polyethylene Glycols; D010763:Phosphorylase b; D006005:Phosphorylases
vernacular_title: Vliianie poliétilenglikolia na assotsiatsiiu myshechnoĭ fosforilazy B.