[The effect of somatostatin on the ileocecal sphincter (ICS) before and after extensive small bowel resection].
The ileocoecal sphincter pressure of rabbits was studied under somatostatin infusion before and after subtotal small bowel resection. Before resection, somatostatin increased the pressure necessary to pass fluid through this zone according to the applied doses. Seven days after resection, a decrease in the ileocoecal sphincter pressure was found, which could not be affected by somatostatin infusion. One year after resection, the reflux pressure was again normal, and the somatostatin effect was similar as to that before resection.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D007080:Ileocecal Valve / Q000187:drug effects* / Q000502:physiology; D007421:Intestine, Small / Q000601:surgery*; D011312:Pressure; D011817:Rabbits; D013004:Somatostatin / Q000494:pharmacology*; D013997:Time Factors
D013004:Somatostatin
Der Einfluss von Somatostatin auf den Ileocoecalsphincter (ICS) vor und nach ausgedehnten Dünndarmresektionen.