A new concept regarding the origin of the junctional and crevicular epithelium in rat molars.
The substitution of the internal enamel epithelium by a squamous epithelium during tooth eruption has been studied histologically in rat molars. Just prior to eruption, cytolysis of the connective tissue covering the cusp tip determines hyperplasia in the oral epithelium. A conspicuous infiltration results. Infiltrated undifferentiated cells form distinct cords which seem to be attracted by the internal enamel epithelium. They reaggregate when they come into its contact and form an underlying epithelium. The process starts in the superficial part and progressively extends towards the cervix. Finally, the internal enamel epithelium is expelled when desquamation begins. The lack of mitoses in both stratum intermedium and internal enamel epithelium and the pyknosis observed in the former, clearly show that the cells of the embryonic dental bell do not take part in the formation of the squamous epithelium as some authors still suppose.
D000565:Ameloblasts / Q000166:cytology; D000818:Animals; D002449:Cell Aggregation; D002467:Cell Nucleus / Q000648:ultrastructure; D003743:Dental Enamel / Q000166:cytology*; D004847:Epithelial Cells; D008963:Molar; D051381:Rats; D014078:Tooth Eruption