Transplanted cultured cells from pregnancy-dependent mammary tumors have a heterogenous developmental potential.
Cultured cells derived from pregnancy-dependent mouse mammary tumors (plaques) when transplanted into the gland-free mammary fat pad display a heterogeneous developmental potential. They not only gave rise to plaques but also produced normal mammary gland, hyperplastic alvoelar nodules (HAN), and autonomous mammary tumors.
D000818:Animals; D002478:Cells, Cultured; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000473:pathology*; D051379:Mice; D009368:Neoplasm Transplantation; D011247:Pregnancy; D011270:Pregnancy, Animal; D014184:Transplantation, Homologous