[Quantifiable morphokinesis of parts of the hypothalamo-adenohypophyseal-gonadal axis of hormonally desexed boars. 4. Studies on boars that have undergone combined treatment with the steroid test substance 547 and norgestrel].
Steroid test substance 547 and Norgestrel were used in a combination treatment of parts of the hypothalamo-adenohypophyseo-gonadal axis of boars. The quantifiable parameters of the morphokinetic effect thus produced (cell nucleus volumes of Nucleus praeopticus medialis hypothalami and its neurons as well as those of Leydig's cells testicle weight, length and diameter of tube, percentage of Leydig's cells, testicle weight, length and diameter of tube, percentage of Leydig's cells) did not differ significantly from the findings obtained from boars treated with Norgestrel only (cf. Dorst and co-workder, 1978). The same combination treatment, however, differed from exclusive Norgestrel treatment by causing the occurrence of socalled castration cells, which led to the assumption of an anti-androgenic effect of such combination treatment.
D000736:Androstenes / Q000494:pharmacology*; D000818:Animals; D002369:Castration / Q000379:methods; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects*; D007700:Kinetics; D007985:Leydig Cells / Q000187:drug effects; D008297:Male; D009474:Neurons / Q000187:drug effects; D009644:Norgestrel / Q000494:pharmacology*; D009929:Organ Size / Q000187:drug effects; D010903:Pituitary Gland, Anterior / Q000187:drug effects; D011301:Preoptic Area / Q000187:drug effects; D013552:Swine / Q000033:anatomy & histology*; D013737:Testis / Q000187:drug effects*; D045165:Testosterone Congeners / Q000494:pharmacology*
D000736:Androstenes; D045165:Testosterone Congeners; D009644:Norgestrel
Zur quantifizierbaren Morphokinese an Gliedern der hypothalamoadenohypophyseo-gonadalen Achse hormonell desexualisierter Eber 4. Mitteilung: Untersuchungen an Ebern, die in einer kombinierten Behandlung mit der Steroidtestsubstanz 547 und Norgestrel unterzogen wurden.