title: Long-term studies on therapy and tolerance of ketoprofen.
abstract: The therapeutic value of non-steroid anti-inflammatory agents for therapy of rheumatoid arthritis is discussed and a long-term study is described which was carried out for up to 12 monts on tolerance of ketoprofen compared with indomethacin. Objective laboratory data were used as criteria for possible influence on organ function. No abnormalities in renal and liver function were observed.
mesh_terms: D001168:Arthritis / Q000378:metabolism; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000201:enzymology; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D007660:Ketoprofen / Q000627:therapeutic use*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D010666:Phenylpropionates / Q000627:therapeutic use*
chemical_list: D010666:Phenylpropionates; D007660:Ketoprofen; D007213:Indomethacin