Stimulation by isoproterenol of erythropoiesis in cultures of dispersed cells of the primitive-streak chick blastodisc.
Low concentrations of isoproterenol stimulated proliferation of precursors of erythroid cells in cultures of cells prepared from the developing chick blastodisc at the stage of the primitive streak. Propranolol blocked this stimulatory action but had no effect upon erythropoiesis in the absence of isoproterenol.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D002642:Chick Embryo; D003470:Culture Media; D004900:Erythroblasts / Q000187:drug effects; D004920:Erythropoiesis / Q000187:drug effects*; D007545:Isoproterenol / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology
D003470:Culture Media; D011433:Propranolol; D007545:Isoproterenol