[Mechanism of the antiexudative action of heparin].
The skin inflammation was induced by xylol application in experiments on rats. Exogenous and endogenous hyperheparinemia was found not to influence the dynamics of microcirculatory changes in the inflammatory area at the onset of its development, vascular permeability being significantly decreased. It is suggested that decreased vascular permeability plays an important role in the mechanism of antiexudative heparin action.
D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects; D005122:Exudates and Transudates / Q000187:drug effects*; D006493:Heparin / Q000494:pharmacology*; D007249:Inflammation / Q000139:chemically induced / Q000503:physiopathology; D051381:Rats; D014992:Xylenes
D014992:Xylenes; D006493:Heparin
K mekhanizmu antiékssudativnogo deĭstviia geparina.