Intoxication with ajmaline in an infant.
We present a case of overdosage of ajmaline in an infant. The appearance of atactic gait and clonic tonic seizures were followed by loss of consciousness, apnea, supraventricular tachycardia, left bundle-branch block, and a prolonged Q-T interval. Cardiopulmonary resuscitation, gastric lavage, and forced diuresis were followed by complete recovery. Continuous electrocardiographic monitoring is mandatory in these cases, and the use of a cardiac pacemaker, respirator, and therapy with antiarrhythmic agents should be considered.
D000061:Accidents, Home; D000284:Administration, Oral; D000404:Ajmaline / Q000008:administration & dosage / Q000506:poisoning*; D001049:Apnea / Q000139:chemically induced; D001145:Arrhythmias, Cardiac / Q000139:chemically induced*; D001259:Ataxia / Q000139:chemically induced*; D002037:Bundle-Branch Block / Q000139:chemically induced; D003244:Consciousness Disorders / Q000139:chemically induced; D004231:Diuresis; D004562:Electrocardiography; D005260:Female; D005751:Gastric Lavage; D006801:Humans; D007223:Infant; D008991:Monitoring, Physiologic; D012151:Resuscitation; D012640:Seizures / Q000139:chemically induced*; D012965:Sodium Chloride / Q000627:therapeutic use; D013607:Tablets; D013610:Tachycardia / Q000139:chemically induced
D013607:Tablets; D000404:Ajmaline; D012965:Sodium Chloride