[Effect of phosphemide on the glycogen content in the organs of white rats].
Tests on albino rats brought evidence that the antineoplastic drug phosphemide, administered to the animals in doses of 10 mg/kg daily for 7 days reduces the glycogen content in the liver on the 5th day of investigation. In the heart, skeletal muscles, kidneys and spleen no changes in the glycogen were noted. Phosphemide produced morphological changes in the spleen and kidneys.
D000818:Animals; D000970:Antineoplastic Agents; D001388:Aziridines / Q000494:pharmacology*; D001389:Azirines / Q000494:pharmacology*; D004347:Drug Interactions; D005260:Female; D006003:Glycogen / Q000032:analysis*; D008297:Male; D009943:Organophosphorus Compounds / Q000494:pharmacology; D051381:Rats; D013997:Time Factors
D000970:Antineoplastic Agents; D001388:Aziridines; D001389:Azirines; D009943:Organophosphorus Compounds; C008880:phosphazine; D006003:Glycogen
Vliianie fosfemida na soderzhanie glikogena v nekotorykh organakh belykh krys.