title: Hypertension in the elderly: special considerations in treatment.
abstract: The goal of antihypertensive therapy in the elderly should be to reduce systolic blood pressure to 140 mm Hg and diastolic pressure to 100 mm Hg without disturbing cerebral or coronary blood flow or depressing cerebral function. This goal can usually be accomplished by using half doses of thiazide diuretics alone or in combination with half doses of hydralazine. Drugs which produce postural hypotension or depress cardiac output and cerebral function should not be used.
mesh_terms: D000368:Aged; D001581:Benzothiadiazines; D004232:Diuretics; D006760:Hospitalization; D006801:Humans; D006830:Hydralazine / Q000008:administration & dosage; D006973:Hypertension / Q000188:drug therapy / Q000628:therapy*; D010349:Patient Compliance; D049993:Sodium Chloride Symporter Inhibitors / Q000008:administration & dosage
chemical_list: D001581:Benzothiadiazines; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors; D006830:Hydralazine