The catalysis of nucleotide polymerization by compounds of divalent lead.
Soluble lead salts and a number of lead-containing minerals catalyze the formation of oligonucleotides from nucleoside 5'-phosphorimidazolides. The effectiveness of lead compounds correlates strongly with their solubility. Under optimal conditions we were able to obtain 18% of pentamer and higher oligomers from ImpA. Reactions involving ImpU gave smaller yields.
D005075:Biological Evolution; D055598:Chemical Phenomena; D002621:Chemistry; D007854:Lead; D009711:Nucleotides; D009841:Oligonucleotides
D009711:Nucleotides; D009841:Oligonucleotides; D007854:Lead