[Action of qualitatively varied proteins in the ration on aspects of the immunobiological reactivity of the body of white rats].
For 37--48 days the action of qualitatively different proteins (caseine jellatine) on some factors of the immunobiological reactivity of growing albino rats of the Wistar lineage was studied. A decline of the body mass and hypoproteinemia maintained on a diet with jellatine by comparison with animals with corresponding factors receiving caseine was revealed. In the spleen, mesenteric lymph nodes and in the small intestine layer proper in rats given a diet with jellatine a reduced number of plasmatic cells and also of the lymphoid series in the epithelial layer of the small intestine villi was disclosed. These animals failed to demonstrate the presence of specific antibodies 3 weeks after immunization with diphtherial anatoxin, whereas the heterohemagglutinines titre was rising. In animals kept on a diet with caseine the proportion of the heterohemagglutinines production and of specific antibodies had a reciprocal character, which manifested itself in a hefty depression of the agglutinines biosynthesis to sheep erythrocytes with an accruing titres of antidiphtherial antibodies.
D000596:Amino Acids / Q000172:deficiency; D000818:Animals; D000918:Antibody Specificity; D000937:Antigen-Antibody Reactions / Q000187:drug effects*; D001835:Body Weight / Q000187:drug effects; D004044:Dietary Proteins / Q000008:administration & dosage*; D004168:Diphtheria Toxoid / Q000008:administration & dosage; D006388:Hemagglutinins / Q000032:analysis; D007114:Immunization; D007421:Intestine, Small / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D013154:Spleen / Q000473:pathology; D013997:Time Factors
D000596:Amino Acids; D004044:Dietary Proteins; D004168:Diphtheria Toxoid; D006388:Hemagglutinins
Deistvie kachestvenno razlichnykh belkov ratsiona na nekotorye storony immunobiologicheskoĭ reaktivnosti organizma belykh krys.