Lipid and steroid hydroperoxides as substrates for the non-selenium-dependent glutathione peroxidase.
The reduction of linoleic acid hydroperoxide catalysed by rat liver cytosol was previously shown to be catalysed by a selenium-dependent glutathione peroxidase. In contrast, the enzyme responsible in guinea-pig liver cytosol is not selenium-dependent and appears to be a glutathione transferase.
D000818:Animals; D003600:Cytosol / Q000201:enzymology; D005979:Glutathione Peroxidase / Q000378:metabolism*; D006168:Guinea Pigs; D008055:Lipids; D008099:Liver / Q000201:enzymology*; D008297:Male; D010544:Peroxidases / Q000378:metabolism*; D010545:Peroxides; D012643:Selenium; D013256:Steroids
D008055:Lipids; D010545:Peroxides; D013256:Steroids; D010544:Peroxidases; D005979:Glutathione Peroxidase; D012643:Selenium