Increase in genetic activity of the polycyclic hydrocarbon benzo[a]pyrene by inhibition of the epoxide hydrase in an activation system in vitro.
D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism / Q000494:pharmacology*; D002460:Cell Line; D002842:Chromatids / Q000187:drug effects; D002869:Chromosome Aberrations; D006224:Cricetinae; D003434:Crossing Over, Genetic / Q000187:drug effects; D003510:Cyclohexanes / Q000494:pharmacology; D004851:Epoxide Hydrolases / Q000037:antagonists & inhibitors*; D004852:Epoxy Compounds / Q000494:pharmacology; D005260:Female; D008862:Microsomes, Liver / Q000378:metabolism; D009153:Mutagens; D010053:Ovary; D051381:Rats
D001580:Benzopyrenes; D003510:Cyclohexanes; D004852:Epoxy Compounds; D009153:Mutagens; D004851:Epoxide Hydrolases