title: UV studies of nucleic acid vase complexation with isoproterenol in different solvents.
abstract: Charge transfer complex formation between nucleic acid bases and isoproterenol was demonstrated from UV absorption measurements. The solvent polarity effects on equilibrium constants were investigated. The solvent systems containing 0.1 N HCl were 20% aqueous ethanol, water, and water containing sodium chloride. The equilibrium constants, calculated from UV absorption data by the application of the Benesi-Hildebrand equation, were small and increased with increasing ionic strength. Equilibrium constant wavelength dependence was demonstrated in some cases.
mesh_terms: D007545:Isoproterenol; D007700:Kinetics; D011687:Purines; D011743:Pyrimidines; D012997:Solvents; D013056:Spectrophotometry, Ultraviolet; D013816:Thermodynamics
chemical_list: D011687:Purines; D011743:Pyrimidines; D012997:Solvents; D007545:Isoproterenol