title: Ultrastructure of chick tendon fibroblast with special reference to secretory mechanism.
abstract: Electron-microscope study of chick tendon fibroblast revealed a constant ultrastructural finding of a microtubular-microfibrillar system and an intimate relationship which existed between the microtubular-microfibrillar system and secretory vacuoles. Additionally, the data from this study suggest a mechanism by which newly synthesized collagen molecules are transported and secreted into the extracellular space to be organized into mature collagen.
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000648:ultrastructure; D002645:Chickens; D003094:Collagen / Q000096:biosynthesis; D003593:Cytoplasm / Q000648:ultrastructure; D005110:Extracellular Space / Q000378:metabolism; D005347:Fibroblasts / Q000378:metabolism / Q000648:ultrastructure*; D008870:Microtubules / Q000648:ultrastructure; D009940:Organoids / Q000648:ultrastructure; D011347:Procollagen / Q000096:biosynthesis; D013710:Tendons / Q000166:cytology* / Q000378:metabolism / Q000648:ultrastructure; D014617:Vacuoles / Q000648:ultrastructure
chemical_list: D011347:Procollagen; D003094:Collagen