title: [Metastasising squamous-cell carcinoma of the skin in a ten-year-old girl].
abstract: Because of recurrent paronychia of the right thumb "granulation" tissue was removed from the nail-bed of a ten-year-old girl. Histological examination revealed a cornified squamous-cell carcinoma. About five months later a lymph-node metastasis was found in the right axilla. After radical dissection of the axillary region further lymph-node metastases were found, as well as a lymphangitic carcinosis with tumour infiltration in the veins. Despite telecobalt radiation there were recurrent retastases which could no longer be removed by operation. Two years after the diagnosis the girl died. Necrospy revealed diffuse tumour infiltration of the soft tissue of the axilla, upper arm, shoulder, neck and thoracic wall on the right, including the breast tissue, with thoracic para-aortic-abdominal and left-sided axillary lymph-node metastases, and lung and pleural metastases bilaterally.
mesh_terms: D000367:Age Factors; D001344:Autopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000473:pathology / Q000601:surgery; D009362:Neoplasm Metastasis / Q000473:pathology; D010304:Paronychia / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology*; D013933:Thumb
vernacular_title: Metastasierendes Plattenepithelkarzinom der Haut mit letalem Verlauf bei einem zehnjährigen Mädchen.