title: Chronic lower leg ulceration in systemic lupus erythematosus.
abstract: Four patients with chronic recurrent deep lower leg ulcerations complicating systemic lupus erythematosus are reported. In each case, highly expressed systemic lupus erythematosus was evident and the ulcers were generally poorly responsive to therapeutic maneuvers and were severely debilitating. This lesion appears to be associated with a poor prognosis.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D011241:Prednisone / Q000627:therapeutic use; D012008:Recurrence; D014183:Transplantation, Heterologous
chemical_list: D011241:Prednisone