[Solid dendritic angiosarcomas (of the hemangioendothelioma and hemangiopericytoma types in the differential diagnosis of malignant lymphomas)].
A group of 11 cases was used for the closer follow-up of an extraskeletal tumour lik Ewing's sarcoma (9). While mostly soft tissues were affected, its localization was variegated. Throughout the long-term follow-up period there was only one case of non-relapse after extirpation. Most of the tumours became generalized within three years. One exceptional case involved generalization after 13 years. The tumour reveals a mostly solid, seemingly organoid pattern, always, however, with reticular foci or sinusoid in nature. The cells, round or dendritic in appearance, have numerous intercellular connections with Weibel Palade granules occasionally demonstrable in their cytoplasm. In foci of peritheliomatous appearance, such as may exceptionally predominate in the tumour, the tumour cells become elongated, contain an abundance of endoplasmic reticulum, and make up a system of integrated basal membranes. According to its structural and cytological properties, the tumour has the nature of angiosarcoma, mostly of the endothelial type, frequently assuming the nature of the pericytic variant. These transitional structural properties just as the tumour' biological behaviour are unlike Ewing's sarcoma and, for that reason, a change of the name is proposed.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006390:Hemangioendothelioma / Q000175:diagnosis*; D006393:Hemangiopericytoma / Q000175:diagnosis*; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012512:Sarcoma, Ewing / Q000175:diagnosis
Solidní dendritické angiosarkomy (hemangioendoteliomatózního a hemangiopericytomatózního typu v diferenciální diagnostice malignínch lymfomů).