title: Spread of Salmonella typhi in a maternity hospital.
abstract: An Asian patient with undiagnosed typhoid fever was admitted to a maternity hospital and delivered within 10 min. Salmonella typhi (phage type D5) was isolated from her blood and from the faeces of her baby. Another women in a different room of the labour suite at the same time acquired the same organism in her faeces; her brother was admitted to the Infectious Diseases Unit 5 weeks later with typhoid fever. Two babies, born over 60 h after the index case was delivered, became faecal excreters of the same strain and one of them also developed S. typhi osteitis of the hip. These two babies and their mothers were in the same ward as each other, but not that occupied by the infected mother and her baby. Nine other excreters in two of the families involved were identified. The index case and her baby were isolated immediately after delivery, and the relevant rooms in the labour suite were adequately disinfected. No evidence of undisinfected equipment used by the index case and the other infected patients was found, and no spread to staff was detected. The mode of spread remains unknown.
mesh_terms: D000293:Adolescent; D000328:Adult; D003428:Cross Infection / Q000635:transmission*; D004196:Disease Outbreaks / Q000453:epidemiology; D004739:England; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000209:etiology*; D012485:Salmonella typhi / Q000302:isolation & purification; D014435:Typhoid Fever / Q000453:epidemiology / Q000235:genetics / Q000635:transmission*