Selective antagonism of 5-fluorouracil cytotoxicity by 4-hydroxypyrazolopyrimidine (allopurinol) in vitro.
D000493:Allopurinol / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D004359:Drug Therapy, Combination; D005472:Fluorouracil / Q000008:administration & dosage / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D007942:Leukemia, Experimental / Q000188:drug therapy* / Q000378:metabolism; D051379:Mice; D009963:Orotic Acid / Q000378:metabolism
D009963:Orotic Acid; D000493:Allopurinol; D005472:Fluorouracil