[Oxygen effect in the therapy of lung cancer].
Nine lung cancer patients were subjected preoperatively to radiotherapy under hypoxia with inhaling of GHM-10 (gas hypoxic mixture). The patients were followed up during 7--12 months. The results obtained evidence the rationality of further studies in this direction, that is of special importance due to introducing of reconstructive--plastic operations on the trachea and bronchi into oncological practice. Thus, there will be a possibility to preserve, in some cases, a porton of the lung. Since the functional status of the lung after surgical and radiation treatment is of primary importance for the duration of patients' survival, the lung tissue protection from side-effects of radiation in irradiating lung tumors may offer good perspectives.
D000230:Adenocarcinoma / Q000378:metabolism; D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000378:metabolism; D002470:Cell Survival; D002478:Cells, Cultured; D006801:Humans; D006931:Hyperbaric Oxygenation; D000860:Hypoxia / Q000378:metabolism; D066298:In Vitro Techniques; D008175:Lung Neoplasms / Q000378:metabolism / Q000532:radiotherapy*; D009368:Neoplasm Transplantation; D010101:Oxygen Consumption; D010313:Partial Pressure; D013997:Time Factors
Kislorodnyĭ éffekt v terapii raka legkogo.