Phototherapy and plasma immunoreactive prostaglandin A values. Its effect in premature infants.
Plasma immunoreactive prostaglandin A (iPGA) values were determined for 14 premature infants before and after 48 hours of phototherapy and in a control group of six age-matched premature infants. At 4 to 8 days of life, the infants who had received phototherapy for 48 hours had significantly lower iPGA values compared with controls. At 2 to 3 days of life, four infants with a clinically apparent patent ductus arteriosus were found to have significantly elevated iPGA values compared with controls. After 48 hours of phototherapy, these infants likewise had a significant decrease in iPGA values compared with controls; in all four infants, the ductus closed spontaneously. Phototherapy is an effective method for decreasing plasma iPGA values in premature infants.
D004374:Ductus Arteriosus, Patent / Q000097:blood* / Q000150:complications; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000628:therapy*; D007567:Jaundice, Neonatal / Q000150:complications / Q000628:therapy*; D010789:Phototherapy; D011454:Prostaglandins A / Q000097:blood*; D011863:Radioimmunoassay; D012127:Respiratory Distress Syndrome, Newborn / Q000097:blood / Q000150:complications
D011454:Prostaglandins A