Effect of underfeeding on the inhibition of gonadotrophin secretion by testosterone propionate in rats.
Single (0 . 25 mg/100 g body wt) or multiple (5 x 20 microgram/100 g) injections of testosterone propionate were given to castrated male rats fed normally or restricted to a 50% intake. Serum FSH and LH levels were higher in the underfed rats and the effectiveness of testosterone propionate in suppressing serum levels of gonadotrophins was increased by underfeeding.
D000818:Animals; D002369:Castration; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D005508:Food Deprivation / Q000502:physiology*; D007986:Luteinizing Hormone / Q000378:metabolism*; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010902:Pituitary Gland / Q000378:metabolism*; D051381:Rats; D013739:Testosterone / Q000494:pharmacology*
D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone