title: Absorption of vitamin C from the human buccal cavity.
abstract: 1. Ascorbic acid was absorbed across the mucosa of the human mouth. 2. Omission of sodium ions from the medium decreased the  absorption of ascorbic acid. 3. The presence of D-glucose, or 3-O-methyl-D-glucose, increased the absorption of ascorbic acid but D-fructose had little effect and D-mannitol had no effect. 4. Calcium ions also increased ascorbic acid absorption probably by a secondary effect on "Na+ fluxes. 5. Buccal mucosa was also permeable to dehydroascorbic acid and D-isoascorbic acid.
mesh_terms: D000042:Absorption; D000328:Adult; D001205:Ascorbic Acid / Q000378:metabolism*; D001692:Biological Transport / Q000187:drug effects; D002118:Calcium / Q000378:metabolism; D003683:Dehydroascorbic Acid / Q000378:metabolism; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism
chemical_list: D012964:Sodium; D005947:Glucose; D001205:Ascorbic Acid; D002118:Calcium; D003683:Dehydroascorbic Acid