title: [Antibacterial and antiviral activity of the polychloroethyl- and beta,beta-dichlorovinylamides of carboxylic acids].
abstract: A number of compounds having antiviral and antibacterial (antistaphylococcal) activity was found in the beta,beta-dichlorvinyl- and alpha-chlor(alpha-oxy)-beta,beta,beta-trichlorethylamide series of carboxylic acids. The antistaphylococcal activity of the compounds under study was found to depend, to a certain extent, ontheir chemical structure, whereas no such dependence was established in respect of their antiviral activity. In the treatment of combined influenza-staphylococcal infection a decrease in antistaphylococcal effect was observed, while antiviral activity remained stable.
mesh_terms: D000577:Amides / Q000494:pharmacology*; D000890:Anti-Infective Agents; D000998:Antiviral Agents; D004305:Dose-Response Relationship, Drug; D004352:Drug Resistance, Microbial; D008826:Microbial Sensitivity Tests; D014753:Vinyl Compounds / Q000494:pharmacology
chemical_list: D000577:Amides; D000890:Anti-Infective Agents; D000998:Antiviral Agents; D014753:Vinyl Compounds
vernacular_title: Antibakterial'naia i antivirusnaia aktivnost' polikhlorétil- i beta,beta-dikhlorvinilamidov karbonovykh kislot.