[Germinating capacity of Clostridium butyricum Jena H 8 in transplantation tumors (author's transl)].
Following parenteral application of spores of Clostridium butyricum their intratumoral germination and oncolysis were demonstrated on a variety of mouse transplantation tumors. The germination and propagation of the clostridia was restricted exclusively to the tumor tissue, they could not be demonstrated bacterioscopically in parallelly run normal tissue specimens. The observed differences of germination and lysis rate are due, in part, to tumor host and transplantate-specific properties.
D000818:Animals; D002455:Cell Division; D003013:Clostridium / Q000254:growth & development*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008954:Models, Biological; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D009369:Neoplasms; D009374:Neoplasms, Experimental / Q000276:immunology / Q000382:microbiology*; D013045:Species Specificity
Das Auskeimungsvermögen von Clostridium butyricum Jena H 8 in transplantationstumoren.