Hyperosmolar coma as etiological factor in the CNS radiation syndrome of rats.
Supralethal dose of whole-body or trunk but not head-irradiation in rats induced hyperosmolar coma accompanied by hypernatremia and hyperkalemia. This clinical entity has presented the symptoms of the CNS radiation syndrome with a characteristic short survival time.
D000818:Animals; D001769:Blood; D001772:Blood Cell Count; D002490:Central Nervous System / Q000503:physiopathology*; D003128:Coma / Q000097:blood* / Q000150:complications; D006400:Hematocrit; D008297:Male; D009994:Osmolar Concentration; D011188:Potassium / Q000097:blood; D011832:Radiation Injuries / Q000097:blood* / Q000150:complications; D051381:Rats; D012964:Sodium / Q000097:blood
D012964:Sodium; D011188:Potassium