title: Radioimmunoassay of secretin in serum.
abstract: A radioimmunoassay for the measurement of immunoreactive secretin has been developed. The assay is specific and sensitive so that 2.8 fmol/ml can be measured. Basal secretin levels in man are generally undetectable and a protein-rich meal does not elicit a secretin response. However, the intraduodenal instillation of HCl leads to a prompt rise in circulating immunoreactive secretin and exogenous secretin administered intravenously is easily and accurately measured.
mesh_terms: D000818:Animals; D000918:Antibody Specificity; D006801:Humans; D011863:Radioimmunoassay; D012633:Secretin / Q000097:blood* / Q000276:immunology; D012756:Sheep
chemical_list: D012633:Secretin