Ocular myasthenia gravis mimicking pseudointernuclear ophthalmoplegia and variable esotropia.
A 70-year-old man with known vascular disease, who had bilateral internuclear ophthalmoplegia, and an 18-month-old girl with a long-term variable esotropia culminating in a postinfectious oculopharyngeal neuropathy both responded with a positive edrophonium chloride (Tensilon) test, strongly suggesting the diagnosis of myasthenia gravis. Both subsequently received maintenance doses of neostigmine methylsulfate (Prostigmin).
D000368:Aged; D003937:Diagnosis, Differential; D004491:Edrophonium; D004948:Esotropia / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009157:Myasthenia Gravis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D009388:Neostigmine / Q000627:therapeutic use; D009886:Ophthalmoplegia / Q000175:diagnosis / Q000209:etiology*; D013285:Strabismus / Q000209:etiology*
D009388:Neostigmine; D004491:Edrophonium