Sister chromatid exchange (SCE) in human lymphocytes. Effect of UV C irradiation and age.
The number of sister chromatid exchanges (SCE) per metaphase was determined in normal human lymphocytes by the Hoechst-Giemsa procedure. UV C irradiation promotes SCE dose-dependent in the range of 0-40 mJ/cm2. No difference of this phenomenon may be observed, compairing young volunteers (20-40 years) with a 60-80-year-old group.
D000328:Adult; D000367:Age Factors; D000368:Aged; D002842:Chromatids / Q000528:radiation effects*; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects*; D008677:Metaphase / Q000528:radiation effects; D008875:Middle Aged; D014466:Ultraviolet Rays