title: [Histochemical study of cerebral cortex cholinesterases during early mammalian ontogeny].
abstract: Histochemical studies have been made on changes in true cholinesterase and pseudocholinesterase in mammalian ontogenesis. It was found that at early ontogenetic stages the enzymes are located mainly in deep layers. In rabbits, early accumulation of the true cholinesterase takes place; evident maximum of the reaction was found directly over the fibres of the cortical white matter during the last days of foetal development and in newborn animals. Accumulation of pseudocholinesterase in myelinating fibers begins at the 7-10th day. In the cortex of human foetuses, evident heterochronous accumulation of cholinesterase was noted, since the enzyme was concentrated mainly in the occipital and frontal parts of the isocortex.
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D002091:Butyrylcholinesterase / Q000378:metabolism*; D002540:Cerebral Cortex / Q000196:embryology* / Q000201:enzymology; D002802:Cholinesterases / Q000378:metabolism*; D006168:Guinea Pigs; D006651:Histocytochemistry; D006801:Humans; D011817:Rabbits
chemical_list: D000110:Acetylcholinesterase; D002091:Butyrylcholinesterase; D002802:Cholinesterases
vernacular_title: Gistokhimicheskoe issledovanie kholinésteraz kory bol'shogo mozga v rannem ontogeneze mlekopitaiushchikh.