title: Retention of phospholipid acyl groups is not characteristic of neoplastic cells in culture.
abstract: Phospholipid acyl group retention of normal and mouse sarcoma virus transformed cell lines has been examined. The cells were fed [1-14C]oleate for 24 h and then grown to non-radioactive medium for 4 days. Both the transformed rat and mouse cell lines continued to release 14C-labeled fatty acids and phospholipids into the culture medium similarly to the uninfected cells, and showed shifts in 14C between phospholipid subclasses. Thus, the phospholipid acyl group stability reported for L cells is not characteristic of oncogenic cells in culture.
mesh_terms: D000215:Acylation; D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured; D007668:Kidney; D007942:Leukemia, Experimental / Q000378:metabolism*; D051379:Mice; D008979:Moloney murine leukemia virus; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats; D012513:Sarcoma, Experimental / Q000378:metabolism*
chemical_list: D010743:Phospholipids