The application of robust non-linear regression methods for fitting hyperbolic Scatchard plots.
The Scatchard plot is an essential tool for the estimation of binding parameters in biochemistry. In certain situations the fitting of a hyperbolic line is required in this context. It is proposed to solve this non-linear regression problem by robust methods. A method according to Huber and Dutter (1974) is outlined and its good applicability is demonstrated.
D003201:Computers; D012044:Regression Analysis; D013223:Statistics as Topic