Renal damage associated with long term use of lithium carbonate.
The authors report 2 cases of renal damage associated with lithium carbonate treatment. The relevant literature is reviewed and supports the claim that the lithium ion may be nephrotoxic. The article concludes with practical recommendations for clinical practice until futher evidence regarding this association is available.
D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D004305:Dose-Response Relationship, Drug; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006801:Humans; D007668:Kidney / Q000187:drug effects*; D007671:Kidney Concentrating Ability / Q000187:drug effects; D008094:Lithium / Q000009:adverse effects* / Q000097:blood / Q000627:therapeutic use; D008297:Male
D008094:Lithium; D003404:Creatinine