title: Efficacy of injectable and tablet formulations of praziquantel against immature Echinococcus granulosus.
abstract: Efficacy of an injectable formulation of praziquantel (given intramuscularly or subcutaneously at a dosage level of 5 mg/kg of body weight) or a tablet formulation (5 mg/kg) against immature Echinococcus granulosus was studied in experimentally infected dogs. The compound was efficacious (100% clearance) if injected via either route or if administered orally.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004443:Echinococcosis / Q000188:drug therapy / Q000662:veterinary*; D005260:Female; D007273:Injections, Intramuscular; D007279:Injections, Subcutaneous; D007546:Isoquinolines / Q000008:administration & dosage* / Q000627:therapeutic use; D008297:Male; D011719:Pyrazines / Q000008:administration & dosage / Q000627:therapeutic use; D013607:Tablets
chemical_list: D007546:Isoquinolines; D011719:Pyrazines; D013607:Tablets