title: Floor pen studies on the anticoccidial efficacy of arprinocid in turkeys.
abstract: Arprinocid was tested against coccidiosis in turkeys reared in floor pens. Contamination of pens with Eimeria meleagrimitis, E. adenoeides, and E. gallopavonis was accomplished by the infected seeder bird technique. Performance improved with increasing levels of arprinocid through 120 ppm, but weight gains were depressed at 180 ppm. Lesion scores were significantly and progressively reduced by treatment with 60, 90, 120, and 180 ppm of arprinocid. Control of lesion scores and performance of birds treated with 120 ppm of arprinocid were comparable to the amprolium (125 ppm) treatment. In a separate experiment, the oocyst passage of E. meleagrimitis and of E. adenoeides was progressively reduced by increasing levels of arprinocid, and sporulation rate was decreased. Sportulation was not obtained in oocysts from birds fed arprinocid at 120 ppm or higher.
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000818:Animals; D001593:Benzyl Compounds / Q000627:therapeutic use; D003048:Coccidiosis / Q000401:mortality / Q000517:prevention & control / Q000662:veterinary*; D003049:Coccidiostats / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004539:Eimeria; D011200:Poultry; D011201:Poultry Diseases / Q000517:prevention & control*; D014422:Turkeys
chemical_list: D001593:Benzyl Compounds; D003049:Coccidiostats; D000225:Adenine