Nuclear localization of aldosterone in rat brain cells assessed by autoradiography.
Autoradiographic studies with 3H aldosterone demonstrate nuclear concentration of hormone in neurons of the hippocampus, septum, allocortical regions and brain stem reticular formation and motor nuclei of cranial nerves and in the meninges. The results suggest that mineralocorticoids have wide ranging effects on different parts of the central nervous system.
D000315:Adrenalectomy; D000450:Aldosterone / Q000378:metabolism*; D000818:Animals; D001345:Autoradiography; D001921:Brain / Q000378:metabolism*; D002467:Cell Nucleus / Q000378:metabolism*; D005260:Female; D009474:Neurons / Q000378:metabolism; D051381:Rats; D014018:Tissue Distribution; D014316:Tritium
D014316:Tritium; D000450:Aldosterone