The effect of an intrauterine device on mast cell numbers and distribution in the hamster uterus.
The effect of an IUD on mast cell numbers and distribution in the uterus was studied in castrated, castrated hormone-treated and cycling hamsters. The device had a stimulatory effect on total mast cell numbers in those animals that received no treatment, peanut oil, or estrogen therapy and in all cycling animals. The device also apparently causes mast cells to be redistributed in the different areas of the uterus. The results indicate that the IUD alters the uterine mast cell response to exogenous hormones and cycle times.
D000818:Animals; D002369:Castration; D002452:Cell Count; D006224:Cricetinae; D004967:Estrogens; D005260:Female; D007434:Intrauterine Devices; D008407:Mast Cells; D011374:Progesterone; D014599:Uterus / Q000166:cytology*
D004967:Estrogens; D011374:Progesterone