title: [Chemical and pharmacological research on pyran derivatives. XIII. Derivatives of 2H-pyrano/3,2-c/quinoline].
abstract: Treatment of N-alkylanilines or diphenylamine with N,N-dialkylethoxycarbonylacetamides in the presence of phosphorus oxychloride afforded 6-alkyl(phenyl)-4-dialkylaminopyrano [3,2-c] quinoline-2,5-(6H)-diones, two molecules of amide being involved in the reaction. In some instances 6-alkyl(phenyl)-4-alkylaminopyrano [3,2-c] quinoline-2,5(6H)-diones were obtained through a partial dealkylation of the amino group. Pharmacological evaluation of some compounds showed no activity on the CNS.
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000187:drug effects; D007202:Indicators and Reagents; D051379:Mice; D011714:Pyrans / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity
chemical_list: D007202:Indicators and Reagents; D011714:Pyrans; D011804:Quinolines
vernacular_title: Ricerche chimiche e farmacologiche su derivati piranici. XIII - Derivati della 2H-pirano[3,2-c]chinolina.