A method for the analysis of sigmoid stimulus-response curves.
This paper describes a method, using an interactive computer programme, for fitting a curve to data which is expected to assume a sigmoid form. The programme is specifically designed to generate best estimates of the limits and maximum slope of stimulus-response curves for the carotid sinus baroreceptor reflex, but is applicable to curve-fitting tasks in other fields such as immunology, pharmacology, biochemistry and neurophysiology.
D000818:Animals; D001794:Blood Pressure; D002346:Carotid Sinus / Q000502:physiology*; D003201:Computers; D004305:Dose-Response Relationship, Drug; D006339:Heart Rate; D008433:Mathematics; D008722:Methods; D011817:Rabbits