The elongation of fatty acids by microsomes and mitochondria from normal and pyridoxine-deficient rat brains.
The developmental profile of fatty acid elongation enzymes of rat brain microsomes and mitochondria and the consequences of pyridoxine deficiency have been investigated. The results suggest that a single enzyme system is responsible for elongation of the various fatty acids by mitochondria whereas the microsomal elongation system is diverse.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D003065:Coenzyme A / Q000378:metabolism; D005227:Fatty Acids / Q000378:metabolism*; D008861:Microsomes / Q000201:enzymology*; D008928:Mitochondria / Q000201:enzymology*; D010171:Palmitoyl Coenzyme A / Q000378:metabolism; D051381:Rats; D026681:Vitamin B 6 Deficiency / Q000201:enzymology*
D005227:Fatty Acids; D010171:Palmitoyl Coenzyme A; D003065:Coenzyme A