[Metabolically stable classes of messenger-like nuclear RNA. II. Existence of homology between the 28S fraction of nuclear RNA, giant non-polyadenylated molecules of heterogeneous nuclear RNA and polyadenylated molecules of cytoplasmic RNA].
The existence and extent of homology between the 28S fraction of messenger-like nuclear RNA on one hand, and giant (greater than 45S) molecules of heterogeneous nuclear RNA and various fractions of cytoplasmic RNA on the other hand were studied by the method of competitive hybridization. The results obtained lead to the conclusion that the poly(A)-subfraction of hnRNA molecules with the size of greater than 15 000 nucleotides contains molecules subjected to rapid but incomplete processing with the formation of chains approximately 5000 nucleotides long (approximately 28S), which are then stored in the nucleus for up to 30 hours. Later polyadenylated and non-polyadenylated molecules of cytoplasmic RNA with the size of less than or equal to 2000 nucleotides are formed from the stored precursors.
D000818:Animals; D002467:Cell Nucleus / Q000032:analysis*; D010856:Columbidae; D004355:Drug Stability; D007700:Kinetics; D008970:Molecular Weight; D009693:Nucleic Acid Hybridization; D011061:Poly A; D012332:RNA, Heterogeneous Nuclear; D012333:RNA, Messenger
D012332:RNA, Heterogeneous Nuclear; D012333:RNA, Messenger; D011061:Poly A
Metabolicheski stabil'nye klassy iadernoĭ RNK informatsionnogo tipa. II. Nalichie gomologii mezhdu 28S fraktsieĭ iadernoĭ RNK, gigantskimi poli (A-)-molekulami geterogennoĭ iadernoĭ RNK i poli (A+)-molekulami tsitoplazmaticheskoĭ RNK.