Alterations in the rate of lipogenesis in vivo in maternal liver and adipose tissue on premature weaning of lactating rats: a possible regulatory role of prolactin.
Removal of pups for 24 h from rats at peak lactation decreased 3H2O incorporation into lipid in vivo in mammary gland by 95%, whereas it was increased in liver (77%) and adipose tissue (330%). These increases were prevented by administration of prolactin. Plasma insulin increased 3-fold on weaning and this was partially prevented by prolactin.
D000273:Adipose Tissue / Q000378:metabolism*; D000818:Animals; D005260:Female; D007774:Lactation; D008055:Lipids / Q000096:biosynthesis*; D008099:Liver / Q000378:metabolism*; D008321:Mammary Glands, Animal / Q000378:metabolism; D011247:Pregnancy; D011388:Prolactin / Q000097:blood / Q000502:physiology*; D051381:Rats; D014886:Weaning
D008055:Lipids; D011388:Prolactin