The influence of acetylsalicylic acid and paracetamol on menstrual blood loss in women with and without an intrauterine contraceptive device.
The influence of ASA and paracetamol on menstural blood loss and on some hematologic parameters was investigated in 23 women without an IUD and 10 women with an IUD. Neither in women with normal nor in women with small defects in the hemostatic mechanism were statistically significant increases in menstrual blood losses observed during treatment with ASA or paracetamol when compared to placebo. There was no linear correlation between bleeding time and basal menstrual blood loss or between the blood losses induced by ASA and paracetamol and the bleeding time.
D000082:Acetaminophen / Q000494:pharmacology*; D000328:Adult; D001241:Aspirin / Q000494:pharmacology*; D004311:Double-Blind Method; D005260:Female; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D007435:Intrauterine Devices, Copper; D008598:Menstruation / Q000187:drug effects*; D013997:Time Factors
D000082:Acetaminophen; D001241:Aspirin