The occurrence of gamma-glutamylphenylalanine in the urine of newborn phenylketonurics.
The urine of untreated phenylketonurics in the first weeks of life contains gamma-glutamylphenylalanine (0.07--0.69 mmol/g creatinine, 12 samples) visible on the normal 2-dimensional electrophoreto-chromatogram. This compound is less prominent or absent when urine from older untreated phenylketonurics is examined and is not seen in normal urine.
D003404:Creatinine / Q000652:urine; D004151:Dipeptides / Q000652:urine*; D005973:Glutamine / Q000652:urine*; D006801:Humans; D007231:Infant, Newborn; D010649:Phenylalanine / Q000097:blood / Q000652:urine*; D010661:Phenylketonurias / Q000097:blood / Q000652:urine*
D004151:Dipeptides; D005973:Glutamine; D010649:Phenylalanine; D003404:Creatinine