[Epithelial displasias of the uterine cervix during pregnancy and its evolution (author's transl)].
During the ten year routing study of smears in 12,300 pregnant women, 180 cases of atypias of the uterine cervix were detected (1.46%). However, only 106 of these had sufficient follow up to allow us to draw useful conclusions. The lesions detected included: 1 invasive carcinoma, 71 atypical epithelial lesions and 34 border lesions of which 20 (58%) showed improvement and 14 (41%) remained unchanged. A comparative sutdy of 11,090 sexually active women who were on high oestrogen combination pills, revealed a similar incidence of cervical lesions (1.27%). The lesions included: 2 invasive carcinomas, 100 epithelial atypias and 38 border lesions of which 44 per cent showed improvement and 55 per cent remained unchanged. Cervical lesions were detected in only 0.5 per cent of women on law oestrogen combination pills. These results indicate that it is almost impossible for the cytologist to arrive at a diagnosis of carcinoma in situ in the pregnant woman or in the woman on the pill. No morphologic guide exists to help establish a prognosis. Only follow up study of the cervical lesion is valuable in this regard. Any lesion remaining 6 to 12 months after the delivery should be removed.
D000328:Adult; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D002584:Cervix Uteri / Q000473:pathology; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage / Q000009:adverse effects; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology*; D002578:Uterine Cervical Dysplasia / Q000139:chemically induced / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014626:Vaginal Smears
D003277:Contraceptives, Oral, Combined
Les atypies épithéliales du col utérin au cours de la grossesse et leur évolution.