Treatment of cold urticaria.
In a single patient with severe essential acquired cold urticaria, the following drug regimes were assessed: diphenhydramine, cyproheptadine, hydroxyzine, terbutaline, cimetidine, hydroxyzine plus cimetidine, and hydroxyzine plus terbutaline. Each regime showed favourable results, but a significance level of P = 0.01 was reached only for (a) hydroxyzine plus cimetidine in the suppression of erythema, and (b) the histamine H1 antagonists in the suppression of wealing.
D000328:Adult; D002927:Cimetidine / Q000627:therapeutic use; D003080:Cold Temperature / Q000009:adverse effects; D003533:Cyproheptadine / Q000627:therapeutic use; D004155:Diphenhydramine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D006919:Hydroxyzine / Q000627:therapeutic use; D008297:Male; D013726:Terbutaline / Q000627:therapeutic use; D014581:Urticaria / Q000188:drug therapy* / Q000209:etiology
D003533:Cyproheptadine; D006919:Hydroxyzine; D002927:Cimetidine; D004155:Diphenhydramine; D013726:Terbutaline