Possible stimulatory effect of retinoic acid on pulmonary macrophages.
Retinoic acid was administered to hamsters suffering from N-nitroso-N-methylurethane-induced fibrosing alveolitis. A significant increase in macrophage numbers was seen in the lungs of retinoid-treated animals as compared to the unsupplemented group.
D000542:Alveolitis, Extrinsic Allergic / Q000139:chemically induced / Q000503:physiopathology; D000818:Animals; D006224:Cricetinae; D008264:Macrophages / Q000187:drug effects / Q000502:physiology*; D009605:Nitrosomethylurethane; D014212:Tretinoin / Q000494:pharmacology*
D014212:Tretinoin; D009605:Nitrosomethylurethane