A material with opioid activity in bovine milk and milk products.
Chloroform-methanol extracts of lyophilized milk, of commercially available dried milk or baby food and of casein digests were tested for opioid activity on the guinea-pig ileum longitudinal muscle-myenteric plexus preparation. Compounds with opioid activity--which proved to be resistant to peptidases--were detected in certain batches of baby food, casein digest, and cow milk in considerably varying amounts.
D000818:Animals; D002364:Caseins / Q000032:analysis; D002417:Cattle; D003611:Dairy Products / Q000032:analysis*; D004723:Endorphins / Q000032:analysis* / Q000494:pharmacology; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008892:Milk / Q000032:analysis*; D013997:Time Factors
D002364:Caseins; D004723:Endorphins