Effect of exercise stress upon the acute toxicity of adriamycin in mice.
The effect of an acute exercise stress upon the acute toxicity of adriamycin was tested. Mice were forced to swim for 30 min following 18 or 23 mg/kg ip of adriamycin. Survival was checked daily for 30 days. The exercise stress did not appear to increase the toxicity of adriamycin in these animals.
D000818:Animals; D004317:Doxorubicin / Q000633:toxicity*; D008297:Male; D051379:Mice; D005082:Physical Exertion; D013312:Stress, Physiological / Q000503:physiopathology*; D013997:Time Factors
D004317:Doxorubicin