title: Symptomatic arteriovenous malformation in infants less than 6 months of age.
abstract: The symptomatology and sequelae of symptomatic system arteriovenous (A-V) malformations in children less than 6 months old make an early diagnosis possible and early treatment mandatory. A group of 156 infants with systemic A-V malformations involving the CNS (81 infants), liver (61 infants), and lungs (14 infants) were studied to compare symptoms, diagnosis, treatment, and outcome. Congestive heart failure was present in 67% of the patients with CNS A-V malformations. Mortality among the patients with CNS A-V fistulas was 64%. Of those patients with hepatic A-V malformations 67% had abdominal masses, 48% congestive heart failure, and 55% died. Pulmonary A-V malformations presented with congestive heart failure 57%, cyanosis 43%, and resulted in a 43% mortality. Early combined medical and surgical therapy offered the best chance for a successful outcome.
mesh_terms: D001165:Arteriovenous Malformations / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D001314:Auscultation; D003490:Cyanosis / Q000209:etiology; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006391:Hemangioma / Q000209:etiology; D006499:Hepatic Artery / Q000002:abnormalities; D006503:Hepatic Veins / Q000002:abnormalities; D006801:Humans; D007223:Infant; D002538:Intracranial Arteriovenous Malformations / Q000150:complications / Q000175:diagnosis; D008297:Male; D011379:Prognosis; D011651:Pulmonary Artery / Q000002:abnormalities; D011667:Pulmonary Veins / Q000002:abnormalities; D013684:Telangiectasis / Q000209:etiology