Effects of presynaptic modulators on Ca2+-induced noradrenaline release from central noradrenergic neurons. Noradrenaline and enkephalin inhibit release by decreasing depolarization-induced Ca2+ influx.
D000818:Animals; D002118:Calcium / Q000378:metabolism / Q000494:pharmacology*; D002490:Central Nervous System / Q000187:drug effects / Q000378:metabolism*; D004347:Drug Interactions; D004723:Endorphins / Q000494:pharmacology*; D004745:Enkephalins / Q000494:pharmacology*; D066298:In Vitro Techniques; D008297:Male; D009270:Naloxone / Q000494:pharmacology; D009474:Neurons / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism* / Q000494:pharmacology; D010646:Phentolamine / Q000494:pharmacology; D011188:Potassium / Q000378:metabolism; D051381:Rats
D004723:Endorphins; D004745:Enkephalins; D009270:Naloxone; D011188:Potassium; D002118:Calcium; D009638:Norepinephrine; D010646:Phentolamine