The structures of tridecaptins B and C (studies on antibiotics from the genus Bacillus. XXV).
On examining the structures of the antibiotics tridecaptins B and C, the constituent amino acids were separated and their chiralities were determined. The constituent fatty acids were identified by gas chromatography and mass spectrometry. Cleavage with N-bromosuccinimide and sequential analysis by EDMAN degradation demonstrates the sequence of the C-terminal side of tridecaptins B and C. Deacylation with polymyxin acylase of tridecaptin B and successive EDMAN degradation revealed the sequence of the N-terminal side of tridecaptin B. Finally partial acid hydrolysis on tridecaptin C clarified the sequence of the N-terminal side of tridecaptin C.
D000596:Amino Acids / Q000032:analysis; D000900:Anti-Bacterial Agents; D001407:Bacillus / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D005227:Fatty Acids / Q000032:analysis; D006868:Hydrolysis; D010455:Peptides / Q000032:analysis
D000596:Amino Acids; D000900:Anti-Bacterial Agents; D005227:Fatty Acids; D010455:Peptides