[New considerations on the role of the mouse skin surface lipids on the "in vivo" penetration of "Schistosoma mansoni" cercariae (author's transl)].
The authors have studied the effect of delipitizing and of the previously extracted skin lipids reapplication on mice experimental infected with Schistosoma mansoni cercariae. The results demonstrated that the amount of living cercariae, not penetrated, recovered after the exposition to the parasite is greater in the delipitized mice than in the other ones. The low amount of worms recovered from the treated mice might be due to the effect of the mouse skin surface lipids not only on stimulating cercarial penetration but also on allowing cercarial transformation to schistosomula during skin crossing.
D000818:Animals; D001700:Biomphalaria / Q000469:parasitology; D005260:Female; D050356:Lipid Metabolism; D051379:Mice; D012547:Schistosoma / Q000502:physiology*; D012867:Skin / Q000378:metabolism*; D012879:Skin Physiological Phenomena
Nuove considerazioni sul ruolo dei lipidi superficiali cutanei di topo nella penetrazione "in vivo" delle cercarie di "Schistosoma mansoni".