[Experimental exacerbation of latent Q rickettsial infection].
The evidence of the prolonged persistence of Coxiella burnetii in experimental animals was obtained. Cyclophosphamide was shown to be capable of activating Q rickettsiosis in guinea pigs, and the period of the aggravation of this infection was found to be accompanied by a decrease in IgG concentration and a relative increase in IgM content.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D002642:Chick Embryo; D003381:Coxiella / Q000276:immunology; D003520:Cyclophosphamide / Q000008:administration & dosage; D006168:Guinea Pigs; D007109:Immunity; D051379:Mice; D011778:Q Fever / Q000139:chemically induced / Q000276:immunology* / Q000382:microbiology; D013154:Spleen / Q000382:microbiology; D013997:Time Factors
D000907:Antibodies, Bacterial; D003520:Cyclophosphamide
Obostrenie latentnoi Ku-rikketsial'noĭ infektsii v éksperimente.