Prostaglandin E1 infusion in the hypoplastic left heart syndrome.
Aortic infusion of prostaglandin E1 in a moribund infant resulted in marked clinical improvement. Appropriate studies were conducted and the diagnosis of hypoplastic left heart syndrome was made. Although the outcome was unaltered, the improved clinical condition allowed us to exclude potentially curable defects such as aortic coarctation and interruption.
D001011:Aorta / Q000002:abnormalities; D001027:Aortography; D004374:Ductus Arteriosus, Patent / Q000150:complications*; D004452:Echocardiography; D006330:Heart Defects, Congenital / Q000188:drug therapy*; D006351:Heart Valves / Q000002:abnormalities; D006352:Heart Ventricles / Q000002:abnormalities; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011458:Prostaglandins E / Q000627:therapeutic use*
D011458:Prostaglandins E