[Role of adreno- and cholinoreactive structures of the hypothalamus in regulating blood coagulation and maintaining it in a fluid state].
Electrical stimulation of anterior and lateral hypothalamus as well as acetylcholin injection into the same areas activated the anticoagulating blood system whereas adrenaline injections activated the coagulating system. The electrical stimulation with certain parameters seems to involve cholinoreactive structures of the hypothalamus, shifting the blood potential towards hypocoagulation. The sitmulation of the paraventricular and ventromedial hypothalamic nuclei with the same current activated the blood coagulating system whereas stimulation of the preoptic lateral or medial areas, medial supraoptic nucleus of the hypothalamus induced no changes in the homeostatic system. The data obtained suggest that the regulation of the blood anticoagulating system involves the anterior hypothalamic area, the suprachiazmatic nucleus, and the rostral part of the lateral hypothalamic area.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D001777:Blood Coagulation; D001931:Brain Mapping; D004558:Electric Stimulation; D004837:Epinephrine / Q000494:pharmacology*; D005342:Fibrinolysis; D007031:Hypothalamus / Q000502:physiology*; D007032:Hypothalamus, Anterior / Q000502:physiology; D008297:Male; D010286:Paraventricular Hypothalamic Nucleus / Q000502:physiology; D011301:Preoptic Area / Q000502:physiology; D051381:Rats; D013495:Supraoptic Nucleus / Q000502:physiology
D000109:Acetylcholine; D004837:Epinephrine
Rol' adreno- i kholinoreaktivnykh struktur gipotalamusa v reguliatsii svertyvaniia krovi i podderzhaniia ee v zhidkom sostoianii.