Effect of phosphate omission on glucose-induced insulin release in vitro.
In the isolated perfused rat pancreas, omission of extracellular phosphate (H2PO-4) significantly reduces the insulin secretion in response to 16.7 mM glucose.
D000818:Animals; D005947:Glucose / Q000494:pharmacology*; D066298:In Vitro Techniques; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007700:Kinetics; D008297:Male; D010179:Pancreas / Q000187:drug effects / Q000378:metabolism*; D010477:Perfusion; D010710:Phosphates / Q000494:pharmacology*; D051381:Rats
D007328:Insulin; D010710:Phosphates; D005947:Glucose