Levamisole in the treatment of cyclical neutropenia.
A child with cyclical neutropenia was observed before and during treatment with levamisole. Marked clinical improvement occurred while on levamisole. Deterioration occurred after stopping treatment. The improvement was not associated with changes in the neutrophil or monocyte counts, nor did tests of phagocytic cell function convincingly demonstrate improvement while the child was on treatment.
D000380:Agranulocytosis / Q000188:drug therapy*; D002675:Child, Preschool; D005260:Female; D005892:Gingivitis, Necrotizing Ulcerative / Q000188:drug therapy*; D006801:Humans; D007958:Leukocyte Count; D007978:Levamisole / Q000627:therapeutic use*; D009503:Neutropenia / Q000097:blood / Q000188:drug therapy*; D010586:Phagocytes / Q000502:physiology
D007978:Levamisole