Incidence and outcome of the respiratory distress syndrome in gram-negative sepsis.
Twenty cases of the adult respiratory distress syndrome (ARDS) in 86 cases of Gram-negative bacteremia were identified. Features of Gram-negative bacteremia associated with the development of ARDS included a history of cardiac disease, hypotension, and thrombocytopenia. The mortality of patients with and without ARDS was 90% and 55%, respectively. The association of hypotension and thrombocytopenia with the subsequent development of ARDS suggests the possible role of endotoxin-induced coagulopathy in this complication.
D003327:Coronary Disease / Q000150:complications; D006801:Humans; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D018805:Sepsis / Q000150:complications*; D012772:Shock, Septic / Q000150:complications; D013921:Thrombocytopenia / Q000150:complications