Human red cell glyoxalase I polymorphism in Denmark and its application to paternity cases.
Phenotypes of glyoxalase I (GLO) were determined in 1220 unrelated adults from all parts of Denmark giving the gene frequencies GLO1 = 0.4311 and GLO2 = 0.5689. The segregation of phenotypes in 59 families and in 455 mother-child pairs was consistent with the assumed autosomal codominant inheritance. The results of an investigation of 379 parternity cases with respect to exclusions of non-fathers by means of the GLO system are reported, and the application of the GLO system to paternity cases is discussed.
D000328:Adult; D003718:Denmark; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005787:Gene Frequency; D006801:Humans; D007791:Lactoylglutathione Lyase / Q000097:blood / Q000235:genetics*; D008190:Lyases / Q000235:genetics*; D008297:Male; D010334:Paternity; D011110:Polymorphism, Genetic
D008190:Lyases; D007791:Lactoylglutathione Lyase