A dominant temperature-sensitive assembly mutant of adenovirus type 2.
An assembly negative temperature-sensitive mutant of Ad2, ts48 was shown to exert dominance over other ts mutants and wild-type virus during coinfection, by inhibiting virion assembly. Dominance was only expressed at the nonpermissive temperature.
D000260:Adenoviruses, Human / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D005799:Genes, Dominant; D005814:Genes, Viral; D009154:Mutation; D010452:Peptide Biosynthesis; D013696:Temperature; D014764:Viral Proteins / Q000096:biosynthesis / Q000235:genetics*; D014779:Virus Replication
D014764:Viral Proteins