title: In vitro studies on the metabolism of dibenzo[c,f]-[1,2]diazepine.
abstract: Dibenzo [c,f]-[1,2] diazepine is a new compound with a tricyclic structure and a double bond between two nitrogen atoms in positions 1 and 2 of the molecule. Its in vitro metabolism has been studied, incubating the compound with rat liver microsomes. Two metabolites have been identified: dibenzo [c,f] - [1,2]diazepine-1-N-oxide and a monohydroxyderivative in the aromatic ring.
mesh_terms: D000818:Animals; D001569:Benzodiazepines / Q000378:metabolism; D001711:Biotransformation; D003984:Dibenzazepines / Q000378:metabolism*; D066298:In Vitro Techniques; D008297:Male; D013058:Mass Spectrometry; D008862:Microsomes, Liver / Q000378:metabolism; D008970:Molecular Weight; D051381:Rats
chemical_list: D003984:Dibenzazepines; D001569:Benzodiazepines