title: Iodine-125--labeled estradiol: a gamma-emitting analog of estradiol that binds to the estrogen receptor.
abstract: 17 beta-[16 alpha-125I]Iodoestradiol has been synthesized by exchange of 16 beta-bromoestradiol with Na125I. The iodinated product is readily separated from the bromo reactant by column chromatography. It concentrates in the rat uterus in vivo and binds avidly and specifically to the uterine estrogen receptor in vitro.
mesh_terms: D000818:Animals; D004958:Estradiol / Q000031:analogs & derivatives* / Q000032:analysis / Q000378:metabolism; D005260:Female; D007457:Iodine Radioisotopes; D011863:Radioimmunoassay / Q000379:methods; D051381:Rats; D011960:Receptors, Estrogen / Q000378:metabolism*; D014599:Uterus / Q000378:metabolism
chemical_list: D007457:Iodine Radioisotopes; D011960:Receptors, Estrogen; D004958:Estradiol