title: Scleroderma with massive regional lymphadenopathy.
abstract: Scleroderma in a two-year-old boy with gross enlargement of the right inguinal lymph nodes, as an early sign, is reported. Repeated lymph node biopsies revealed non-characteristic reactive changes and hyperplasia, but eventually histological examination of skin and muscle from the right leg were diagnostic. The effect of one year of D-penicillamine therapy is briefly mentioned.
mesh_terms: D002675:Child, Preschool; D006801:Humans; D008206:Lymphatic Diseases / Q000188:drug therapy; D008297:Male; D010396:Penicillamine / Q000627:therapeutic use; D012595:Scleroderma, Systemic / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D010396:Penicillamine