title: [Management of persistent ductus arteriosus in the newborn with respiratory insufficiency].
abstract: Sixteen newborn babies with severe respiratory distress and patent ductus arteriosus with congestive heart failure are presented. Fifteen of them were premature and one at full term. Management consisted of the accepted medical and ventilatory aids such as digitalis, diuretics, ventilators, etc. Thirteen cases were given indomethacin with clinical closure in five of them (38%). Ten cases underwent surgical closure with 30% mortality. It is recommended that these patients be given indomethacin inicially; if there is no response in 36 hours surgical closure of the duct should be performed prior to progressive deterioration and eventual death.
mesh_terms: D000284:Administration, Oral; D004077:Digoxin / Q000627:therapeutic use; D004374:Ductus Arteriosus, Patent / Q000188:drug therapy* / Q000601:surgery; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage* / Q000627:therapeutic use; D007223:Infant; D007231:Infant, Newborn; D007440:Intubation; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000188:drug therapy* / Q000601:surgery
chemical_list: D004077:Digoxin; D005665:Furosemide; D007213:Indomethacin
vernacular_title: Manejo del conducto arterioso persistente en el recién nacido con insuficiencia respiratoria.