Vitrectomy in experimental endophthalmitis: Part II--Bacterial endophthalmitis.
Three methods of treatment for Staphylococcus aureus endophthalmitis were compared: subconjunctival injection with intramuscular gentamicin, intravitreal injection with intramuscular gentamicin, and vitrectomy using infusion solution containing gentamicin along with intramuscular gentamicin. Subconjunctival injection with intramuscular gentamicin was not successful in treating infection. Intravitreal injection with intramuscular gentamicin and vitrectomy with intramuscular gentamicin were equally effective in eradicating infection; however, the combination of vitrectomy and intramuscular gentamicin provided clearer vitreous with greater fundus detail.
D000818:Animals; D003228:Conjunctiva; D005069:Evaluation Studies as Topic; D005128:Eye Diseases / Q000188:drug therapy / Q000601:surgery*; D005839:Gentamicins / Q000008:administration & dosage / Q000627:therapeutic use; D007267:Injections; D007273:Injections, Intramuscular; D011817:Rabbits; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000601:surgery*; D014822:Vitreous Body / Q000601:surgery*
D005839:Gentamicins