Chronic gouty nephropathy treated by long-term hemodialysis and allopurinol.
A patient with intractable tophaceous gout and advanced renal failure responded favorably to treatment by long-term hemodialysis and administration of allopurinol. Plasma uric acid levels returned to normal, tophi decreased in size, and the frequency of attacks of gout decreased markedly and permitted the patient to return to full-time employment.
D000493:Allopurinol / Q000627:therapeutic use*; D006073:Gout / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000209:etiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D013997:Time Factors; D014527:Uric Acid / Q000097:blood
D014527:Uric Acid; D000493:Allopurinol