Uveoscleral flow of aqueous humor in the normal dog.
Fluorescein-labeled dextran and sodium fluorescein perfused in the posterior chamber of the normal dog eye egressed through the trabecular meshwork and intrascleral plexus, as well as posteriorly through the ciliary body into the suprachoroidal space and the sclera. Intraocular pressures of 20, 25, 30, and 60 mm of Hg did not produce detectable changes in the fluorescein-labeled dextran movement. Topical 1% atropine and 10% phenylephrine did not affect posterior passage of sodium fluorescein; 2% pilocarpine impeded posterior passage, causing an accumulation of sodium fluorescein and associated fluorescence in the anterior ciliary body.
D000818:Animals; D001082:Aqueous Humor / Q000187:drug effects / Q000502:physiology*; D002924:Ciliary Body / Q000502:physiology; D004285:Dogs / Q000502:physiology*; D005452:Fluoresceins; D007429:Intraocular Pressure; D010862:Pilocarpine / Q000494:pharmacology; D012590:Sclera / Q000502:physiology*; D014602:Uvea / Q000502:physiology*
D005452:Fluoresceins; D010862:Pilocarpine