The rapid extraction of paraquat from plasma using an ion-pairing technique.
A method for the quantitative extraction of paraquat from plasma is described. The method relies on the use of an organic-soluble ion pair of paraquat with dodecyl sulphate. The use of the extraction procedure in conjunction with the dithionite colour reaction gives a method which is suitable for emergency estimations with a sensitivity limit of 50 micrograms/l. The extraction procedure alone offers a new first step in the clean up of paraquat for analysis by other methods.
D000433:1-Propanol; D003124:Colorimetry / Q000379:methods; D004227:Dithionite; D006801:Humans; D008722:Methods; D008752:Methylene Chloride; D010269:Paraquat / Q000097:blood* / Q000302:isolation & purification; D012967:Sodium Dodecyl Sulfate; D012997:Solvents; D013056:Spectrophotometry, Ultraviolet
D012997:Solvents; D004227:Dithionite; D012967:Sodium Dodecyl Sulfate; D008752:Methylene Chloride; D000433:1-Propanol; D010269:Paraquat