title: Resistance to thiabendazole in a field population of Ostertagia circumcincta from sheep.
abstract: A population of Ostertagia circumcincta from sheep has been found which, in field and laboratory trials, showed a lack of response to the recommended dose (44 mg/kg) of thiabendazole, suggesting that a degree of resistance exists to this anthelmintic. Preliminary experiments indicated a less than expected response to levamisole. This was not confirmed in a laboratory trial and therefore resistance to this anthelmintic has not been shown conclusively.
mesh_terms: D000818:Animals; D004351:Drug Resistance; D005243:Feces / Q000469:parasitology; D010029:Ostertagiasis / Q000469:parasitology / Q000662:veterinary*; D010270:Parasite Egg Count; D012756:Sheep; D012757:Sheep Diseases / Q000469:parasitology*; D013827:Thiabendazole / Q000627:therapeutic use*; D014251:Trichostrongyloidea / Q000187:drug effects*; D014252:Trichostrongyloidiasis / Q000662:veterinary*
chemical_list: D013827:Thiabendazole