Aporphines. 25-trimethylislyl derivatives of N-methyl and N-propyl aporphines: gas chromatographic and mass spectrometric properties.
A series of synthetic, semisynthetic and naturally occurring aporphine alkaloids were converted to the O-trimethylsilyl derivatives, and analyzed by gas chromatography mass spectrometry. A discussion of structurally informative fragment ions along with gas chromatographic data is presented. Their applicability to the analysis of biological metabolites of apomorphine, a CNS active structural analog of dopamine, is discussed.
D001058:Apomorphine / Q000031:analogs & derivatives / Q000032:analysis; D001060:Aporphines / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D002849:Chromatography, Gas; D008401:Gas Chromatography-Mass Spectrometry; D013058:Mass Spectrometry; D012825:Silicon / Q000032:analysis*; D014297:Trimethylsilyl Compounds / Q000032:analysis*
D001060:Aporphines; D014297:Trimethylsilyl Compounds; D001058:Apomorphine; D012825:Silicon