title: Assignment of the H-Y antigen gene to the short arm of chromosome Y.
abstract: We have presented two cases strongly suporting a Y chromosome short-arm location for the H-Y antigen gene. The first case was HY antigen-positive with an isochromosome for the short arm of the Y with no long arm of the Y being present. The other case was H-Y antigen-negative in fibroblasts from an individual with a 46,X,i(Yq) karyotype with no short arm of the Y present. The two cases presented also confirmed previous reports that the testicular forming gene is also located on the short arm of chromosome Y.
mesh_terms: D002648:Child; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002877:Chromosomes, Human / Q000648:ultrastructure; D005260:Female; D005796:Genes; D006182:H-Y Antigen / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D012729:Sex Chromosome Aberrations / Q000235:genetics*; D012730:Sex Chromosomes; D014998:Y Chromosome
chemical_list: D006182:H-Y Antigen