Transketolase activity in psychiatric patients.
The thiamine status of 42 physically healthy nonalcoholic psychiatric inpatients was evaluated by measuring transketolase activity in a hemolysate of their red blood cells, before and after addition of thiamine pyrophosphate to the hemolysate. Sixteen patients (38%) showed evidence of thiamine deficiency. Five of these patients had received thiamine-containing vitamins for a period of from 2 fo 47 days prior to testing, suggesting that poor nutrition may not fully account for the thiamine deficiency observed.
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000201:enzymology*; D008875:Middle Aged; D013831:Thiamine / Q000627:therapeutic use; D013832:Thiamine Deficiency / Q000201:enzymology; D014174:Transketolase / Q000097:blood*
D014174:Transketolase; D013831:Thiamine