[Precursors of arteriosclerosis in childhood. Protocol and firsts results concerning plasma lipids and carbohydrate tolerance in 520 school children at Pordenone (Italy) (author's transl)].
The cardiological centers of Pordenone and Cittadella (Italy) organized by the Institute of Clinica Medica II of Padua University, have carried out a study on the "Precursors of arteriosclerosis in children", according to a WHO protocol. In this paper some results of the Pordenone study are reported, concerning serum cholesterol (TC), triglycerides (TG) and blood glucose 1 h after 1 g/Kg glucose per os. 520 school children, males and females, aged 6, 9, 12, 15 years, entered the study. Mean serum TC resulted significantly higher at age 12 as compared to the other age classes. Serum TG progressively increased with age. Mean serum TC and TG in our italian children and adolescents were silimar to those reported in studies from other countries. Blood glucose resulted significantly higher in children than in adolescents. The distribution of the blood glucose values was bimodal. After having arbitrarily fixed cut-off points for serum TC, TG and blood glucose, the prevalence of hyperlipidemia and hyperglycemia was determined. The prevalence figures have shown that at the pediatric age it is possible to identify subjects at "risk" of developing arteriosclerosis.
D000293:Adolescent; D000367:Age Factors; D001161:Arteriosclerosis / Q000453:epidemiology*; D001786:Blood Glucose; D002648:Child; D002784:Cholesterol / Q000097:blood; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D006943:Hyperglycemia / Q000150:complications; D006949:Hyperlipidemias / Q000150:complications; D007558:Italy; D008055:Lipids / Q000097:blood*; D008297:Male; D012306:Risk; D014280:Triglycerides / Q000097:blood
D001786:Blood Glucose; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol
Precursori dell'arteriosclerosi nell'infanzia. Protocollo di studio e primi risultati concernenti i lipidi plasmatici e la tolleranza ai carboidrati in un gruppo di bambini ed adolescenti de Pordenone.