Effect of ionic environment on densities of membrane-associated particles in presynaptic membranes observed in freeze-fractured synaptosomes.
The effects of high-K and high-Ca in the incubation medium on membrane-associated particles of the presynaptic membranes were examined. There was a marked increase in the density of protoplasmic fracture face after incubation in the high-K or high-Ca medium.
D000818:Animals; D002118:Calcium / Q000494:pharmacology; D005614:Freeze Fracturing; D006168:Guinea Pigs; D008854:Microscopy, Electron; D011188:Potassium / Q000494:pharmacology; D013570:Synaptic Membranes / Q000187:drug effects / Q000648:ultrastructure*; D013574:Synaptosomes / Q000187:drug effects / Q000648:ultrastructure*
D011188:Potassium; D002118:Calcium