Isoflavones and hypercholesterolemia in rats.
Isoflavones isolated from three commonly used pulses such as Bengalgram (Cicer arietinum), greengram (Phaseolus aureus) and blackgram (Phaseolus mungo) and p-coumaric acid were supplemented to hypercholesterolemia-inducing diet of rats. Among isoflavones, Biochanin A and Formononetin showed hypolipidemic activity but diadzein did not; p-coumaric acid also produced a significant reduction in serum cholesterol levels.
D000818:Animals; D002784:Cholesterol / Q000097:blood; D002934:Cinnamates / Q000494:pharmacology*; D003296:Cooking; D003373:Coumaric Acids / Q000302:isolation & purification / Q000494:pharmacology*; D007887:Fabaceae / Q000032:analysis; D005419:Flavonoids / Q000494:pharmacology*; D006937:Hypercholesterolemia / Q000139:chemically induced*; D007529:Isoflavones / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D010743:Phospholipids / Q000097:blood; D010946:Plants, Medicinal; D051381:Rats; D014280:Triglycerides / Q000097:blood
D002934:Cinnamates; D003373:Coumaric Acids; D005419:Flavonoids; D007529:Isoflavones; D010743:Phospholipids; D014280:Triglycerides; D002784:Cholesterol