The effect of piroxicam on platelet aggregation.
Piroxicam inhibited aggregation of human and dog platelets caused by collagen, but not by adenosine diphosphate (ADP). Release of platelet ADP was inhibited by piroxicam.
D000244:Adenosine Diphosphate / Q000037:antagonists & inhibitors / Q000378:metabolism; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism; D003094:Collagen / Q000494:pharmacology; D004285:Dogs; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects*; D011725:Pyridines / Q000494:pharmacology*; D013843:Thiazines / Q000494:pharmacology*
D000893:Anti-Inflammatory Agents; D011725:Pyridines; D013843:Thiazines; D000244:Adenosine Diphosphate; D003094:Collagen