Evidence that 5 alpha-reduction of delta 4,3-ketosteroids may be more important for their androgenic than their luteinizing hormone-inhibiting activity.
D000728:Androgens / Q000502:physiology*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002369:Castration; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D008696:Methandrostenolone / Q000494:pharmacology*; D009929:Organ Size / Q000187:drug effects; D010084:Oxidation-Reduction; D011467:Prostate / Q000187:drug effects / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D012313:RNA / Q000378:metabolism; D051381:Rats; D013739:Testosterone / Q000378:metabolism / Q000494:pharmacology*
D000728:Androgens; D011506:Proteins; D013739:Testosterone; D012313:RNA; D007986:Luteinizing Hormone; D008696:Methandrostenolone