title: Pancuronium bromide precurarisation. II An evaluation of clinical aspects in patients of female sex.
abstract: The authors have studied the effects of precurarisation by means of pancuronium on 120 female patients by using three multiple doses of pancuronium bromide. The authors have demonstrated that the dose of pancuronium, capable of abolishing almost completely fasciculations and postoperative succinylcholine myalgias, corresponds to 0.009 mg/kg. This dose has proved to be most efficient in causing a considerable increase in subjective precurarisation symptoms (Heavy eye-lids, blurred vision etc.). Such symptoms have never caused even the least discomfort to the patients. The authors have finally demonstrated that the doses of pancuronium employed cause a decrease in V.C. within limits that do not, however, compromise ventilation.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D009119:Muscle Contraction / Q000187:drug effects*; D010149:Postoperative Pain / Q000517:prevention & control*; D010197:Pancuronium / Q000008:administration & dosage / Q000494:pharmacology*; D013390:Succinylcholine / Q000037:antagonists & inhibitors*; D014797:Vital Capacity / Q000187:drug effects
chemical_list: D013390:Succinylcholine; D010197:Pancuronium