Malignancy in a 19-year experience of adult celiac disease.
Malignancy has developed in 10 of 93 patients with celiac disease who attended this hospital from 1959 to 1978. Four patients developed lymphoma, 5 a squamous carcinoma of the esophagus, and 1 an adenocarcinoma of the ileum. Because the majority of patients were ingesting varying amounts of gluten at the time of their follow-up no conclusion can be drawn about the possible role of a gluten-free diet in the prevention of malignancy.
D000230:Adenocarcinoma / Q000150:complications* / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D000368:Aged; D001315:Australia; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000453:epidemiology; D002446:Celiac Disease / Q000150:complications* / Q000178:diet therapy; D004938:Esophageal Neoplasms / Q000150:complications* / Q000453:epidemiology; D005260:Female; D005983:Glutens; D006801:Humans; D007082:Ileum; D007414:Intestinal Neoplasms / Q000150:complications* / Q000453:epidemiology; D008223:Lymphoma / Q000150:complications* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012306:Risk
D005983:Glutens