[Early scanning electron microscopy changes of the surface of the leaflets of orthotopic transplanted glyceraldehyd-conditioned conus-pulmonalis xenografts. An experimental study in dogs].
The surface of the leaflets of orthotopic transplanted glutaraldehyd-conditioned conus-pulmonalis xenografts show when analysed by a scanning microscope the following constant changes. Within seconds the surface of the leaflets is covered by a grainy layer of proteins followed by fibrin threads. Cellular elements of the blood--like platelets, white blood cells, macrophages and microthrombi--are incorporated in the fibrin network. This leads, after several weeks to a fibrous layer especially over the stiff parts of the valve. No endothelium was seen even after 6 months.
D000818:Animals; D001705:Bioprosthesis; D001773:Blood Cells / Q000648:ultrastructure; D001798:Blood Proteins; D004285:Dogs; D005337:Fibrin; D006350:Heart Valve Prosthesis; D008855:Microscopy, Electron, Scanning; D011655:Pulmonary Embolism / Q000517:prevention & control; D011664:Pulmonary Valve / Q000601:surgery* / Q000648:ultrastructure; D013552:Swine; D013997:Time Factors; D014183:Transplantation, Heterologous
D001798:Blood Proteins; D005337:Fibrin
Frühe rasterelektronenoptische Oberflächenveränderungen nach orthotoper Pulmonalklappen-Xenotransplantation durch glutaraldehyd-konditionierte Schweineklappen. Eine experimentelle Studie an Hunden.