A syndrome of hereditary tyrosinemia in mink (Mustela vison Schreb.).
A hereditary disease in mink (Mustela vison Schreb.) leading to death when the affected kits are about six weeks old has been investigated. The disorder is inherited as a simple autosomal recessive character. Strongly elevated plasma tyrosine concentration is an outstanding feature of the disease. An enzyme defect in tyrosine aminotransferase (EC 2.6.1.5) or 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) is considered together with the possibility of a parallel between the disease in mink and the disease tyrosinosis or hereditary tyrosinemia in man.
D000592:Amino Acid Metabolism, Inborn Errors / Q000097:blood / Q000235:genetics / Q000662:veterinary*; D000818:Animals; D005260:Female; D008297:Male; D008907:Mink / Q000097:blood*; D010375:Pedigree; D013577:Syndrome; D014443:Tyrosine / Q000097:blood*
D014443:Tyrosine