title: Pernicious anaemia and granulomatous skin lesions in a case of common variable hypogammaglobulinaemia.
abstract: A 45-year-old woman is reported with a history of recurrent bacterial infections since childhood; at the age of 37 years she developed recurrent ulcerated lesions around her mouth, in the groins and buttocks, which histologically contained small, non-caseating granulomas. A year latter when being treated for empyema, she was found to have common variable hypogammaglobulinaemia. Three years after this she developed a megaloblastic anaemia of vitamin B12-deficiency type.
mesh_terms: D000361:Agammaglobulinemia / Q000150:complications* / Q000235:genetics; D000752:Anemia, Pernicious / Q000209:etiology*; D005260:Female; D006099:Granuloma / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D010375:Pedigree; D012871:Skin Diseases / Q000209:etiology*