title: Preparation of diastereomeric urethane derivatives of atropine and l-hyoscyamine using (-)-1-phenylethylisocyanate.
abstract: Diastereomeric urethane derivatives of atropine (d,l-hyoscyamine) and l-hyoscyamine were prepared by reacting the alkaloids with (-)-1-phenylethylisocyanate. The derivatives, as the picrate ion-pairs, were characterized by their melting points, optical rotations, elemental analyses, and IR, NMR, and UV-visible spectra.
mesh_terms: D001286:Atropine Derivatives / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D003485:Cyanates; D009682:Magnetic Resonance Spectroscopy; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014520:Urethane / Q000031:analogs & derivatives / Q000138:chemical synthesis
chemical_list: D001286:Atropine Derivatives; D003485:Cyanates; D014520:Urethane