Systemic thermotherapy (whole body hyperthermia).
This is an article reviewing the literature and our experience to date (six months) in the treatment of cancer using whole body hyperthermia in the first 60 patients. WBHT is an effective method of treating cancer. Patients were treated for a total of eight hours, 180 degrees F for two hours. WBHT was induced by means of two high-flow water filled blankets. Toxicity included fatigue, nausea, diarrhea and first degree burns. There was no evidence of visceral damage. There were no mortalities during the procedure. Objective responses were 50%, subjective responses were 65%. The literature demonstrates and our study confirms that under closely monitored conditions, WBHT is a feasible, safe and active anti-cancer therapy. WBHT may be safely used as an adjunct to other active cancer therapies including X-ray therapy and chemotherapy.
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology; D004260:DNA Repair; D004273:DNA, Neoplasm / Q000378:metabolism; D006979:Hyperthermia, Induced; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000000981:diagnostic imaging / Q000276:immunology / Q000378:metabolism / Q000628:therapy; D010100:Oxygen / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects; D012334:RNA, Neoplasm / Q000378:metabolism; D011859:Radiography; D012510:Sarcoma 180 / Q000628:therapy; D014184:Transplantation, Homologous
D000970:Antineoplastic Agents; D004273:DNA, Neoplasm; D012334:RNA, Neoplasm; D010100:Oxygen