[Nasosinusal polyposis and aspirin intolerance. Fernand Widal-Lermoyez syndrome].
The authors describe the clinical picture of the aspirin idiosyncrasy and propose to call this peculiar entity: syndrom of Widal and Lermoyez. They compare 25 cases of aspirin nasal polyposis with 26 other cases of various etiologies. Other substances than aspirin seem to be charged. The complications are regular with severe asthma and infection. The pathogenesis is discussed, excluding an allergic mechanism; it remain not quite clear. Essentially prophylactic, the treatment is poor and difficult.
D000328:Adult; D001241:Aspirin / Q000009:adverse effects* / Q000494:pharmacology; D001249:Asthma / Q000209:etiology; D003937:Diagnosis, Differential; D004342:Drug Hypersensitivity / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D009298:Nasal Polyps / Q000209:etiology* / Q000473:pathology; D010255:Paranasal Sinus Neoplasms / Q000209:etiology* / Q000473:pathology; D013577:Syndrome
D001241:Aspirin
Polypose naso-sinusienne et maladie à l'aspirine. Syndrome de Fernand Widal et Lermoyez.