Upper tract management when posterior urethral valve ablation is insufficient.
Of 105 boys with posterior urethral valves managed during a 10-year period most were managed by primary valve ablation. However, 39 of these boys required concomitant or additional procedures to 71 massively dilated ureters because of azotemia, infection and/or progressive upper tract deterioration. In 17 boys 25 ureters could be reconstructed primarily by varying degrees of ureteral tailoring. When there was severe infection, azotemia and/or doubt as to the function of the affected renal unit, staged reconstruction was initiated by cutaneous ureterostomy. One-fourth of these ureterostomy diverted children died of azotemia despite free urinary drainage. Those who went on to have staged reconstruction, despite multiple surgical procedures, retained intact urinary systems with acceptable function.
D001424:Bacterial Infections / Q000150:complications; D002648:Child; D002675:Child, Preschool; D062109:Dermatologic Surgical Procedures; D004108:Dilatation, Pathologic; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D018805:Sepsis / Q000150:complications; D014511:Uremia / Q000150:complications; D014515:Ureteral Diseases / Q000209:etiology / Q000601:surgery; D014521:Urethra / Q000002:abnormalities* / Q000601:surgery; D014547:Urinary Diversion; D014552:Urinary Tract Infections / Q000150:complications