Association of HLA antigens and primary open-angle glaucoma.
HLA testing of 55 patients with primary open-angle glaucoma revealed no increased frequencies of any of 17 HLA-A and 29 HLA-B antigens. However, the subgroup with a known family history of primary open-angle glaucoma had an increase in the frequency of the HLA-B12 antigen (48%). Intrafamily studies might further define the strength and importance of this association.
D005260:Female; D005901:Glaucoma / Q000235:genetics / Q000276:immunology*; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008297:Male
D006680:HLA Antigens