Effect of the transition-state analogue, delta-N-(phosphonacetyl)-L-ornithine on citrulline synthesis in isolated rat-liver mitochondria and on urea synthesis in isolated rat hepatocytes.
D000818:Animals; D001639:Bicarbonates / Q000378:metabolism; D002956:Citrulline / Q000096:biosynthesis*; D005260:Female; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D009943:Organophosphorus Compounds / Q000494:pharmacology*; D009952:Ornithine / Q000031:analogs & derivatives* / Q000494:pharmacology; D009954:Ornithine Carbamoyltransferase / Q000378:metabolism*; D010746:Phosphonoacetic Acid / Q000031:analogs & derivatives / Q000494:pharmacology*; D051381:Rats; D014508:Urea / Q000096:biosynthesis*
D001639:Bicarbonates; D009943:Organophosphorus Compounds; D002956:Citrulline; D014508:Urea; D009952:Ornithine; D009954:Ornithine Carbamoyltransferase; D010746:Phosphonoacetic Acid