title: Collagenolytic activity of eosinophilic granuloma in vitro.
abstract: Lytic activity of eosinophilic granuloma and other tumours was studied in vitro on collagen substrate. Collagen degradation was measured through the release of hydroxyproline-rich peptides into the medium. The in vitro lytic action was at a maximum in the case of EG and was correlated with the presence of histiocytic cells.
mesh_terms: D001859:Bone Neoplasms / Q000378:metabolism; D002478:Cells, Cultured; D002648:Child; D003094:Collagen / Q000378:metabolism*; D004803:Eosinophilic Granuloma / Q000378:metabolism*; D006801:Humans; D006909:Hydroxyproline / Q000032:analysis
chemical_list: D003094:Collagen; D006909:Hydroxyproline