Experimental cryptococcal myocarditis.
Rabbits and rats developed myocarditis on the 16th, 30th, and 60th day after intrarenal inoculation with Cryptococcus neoformans. The cardiac lesions consist of focal necrosis with infiltrations of small round cells in the myocardium. Cryptococcal antigens were demonstrated by a direct immunofluorescent antibody method in the damaged myocardial lesions. Cryptococcus neoformans itself was found by periodic acid-Schiff stain in the damaged myocardial lesions.
D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis; D003453:Cryptococcosis / Q000473:pathology; D008297:Male; D009205:Myocarditis / Q000209:etiology* / Q000473:pathology; D009206:Myocardium / Q000276:immunology / Q000473:pathology; D011817:Rabbits; D051381:Rats
D000942:Antigens, Bacterial