Amino acid composition and sequence of crinia-angiotensin, an angiotensin II-like endecapeptide from the skin of the Australian frog Crinia georgiana.
Methanol extracts of the skin of the Australian amphibian Crinia georgiana contain large amounts of crinia-angiotensin II, a new angiotensin II-like peptide. This differs sharply from the conventional octapeptide angiotensins II in having attached the tripeptide Ala-Pro-Gly- to the N-terminus, and having an Ile residue substituted for the Val residue at position 6 from the C-terminus. Small amounts of angiotensin-like peptides have been traced, by radioimmunoassay, in skin extracts of some other Crinia species.
D000595:Amino Acid Sequence; D000804:Angiotensin II; D000809:Angiotensins; D000818:Animals; D001001:Anura; D010455:Peptides / Q000302:isolation & purification; D011863:Radioimmunoassay; D012867:Skin / Q000032:analysis*; D013045:Species Specificity
D000809:Angiotensins; D010455:Peptides; D000804:Angiotensin II; C021651:crinia-angiotensin