title: [Antigenic and biological characteristics of influenza A1 viruses isolated in the 1977 pandemic].
abstract: Investigations of the antigenic and biological properties of the causative agents of the 1977 influenza epidemic revealed their appurtenance to the old subtype A1 of influenza virus which had disappeared from circulation 20 years ago. A comparative study of A1 viruses isolated in 1947--1956 and A1/77 established closer relationship of the latter to the causative agents of 1949 and 1950 epidemics. The "old" and newly isolated viruses 4ere also closely related biologically. The similarity of influenza A1/77 viruses with the agents of the pandemic cycle of A1 in 1947--1956 is a convincing confirmation of the hypothesis of Francis-Davenport and Smorodintsev-Luzyanina.
mesh_terms: D000956:Antigens, Viral / Q000032:analysis*; D004196:Disease Outbreaks / Q000453:epidemiology*; D006389:Hemagglutinins, Viral / Q000032:analysis; D006801:Humans; D009980:Influenza A virus / Q000276:immunology* / Q000302:isolation & purification; D007251:Influenza, Human / Q000453:epidemiology / Q000382:microbiology*; D009439:Neuraminidase / Q000032:analysis; D012800:Siberia
chemical_list: D000956:Antigens, Viral; D006389:Hemagglutinins, Viral; D009439:Neuraminidase
vernacular_title: Antigennaia i biologicheskaia kharakteristika virusov grippa A1, izolirovannykh v pandemiiu 1977 g.