Thymidine 5'-O-pivaloate. A prodrug derivative of thymidine with potential applications in high-dose methotrexate therapy.
D000818:Animals; D004247:DNA / Q000378:metabolism; D004359:Drug Therapy, Combination; D007700:Kinetics; D007939:Leukemia L1210 / Q000188:drug therapy*; D008297:Male; D008727:Methotrexate / Q000037:antagonists & inhibitors* / Q000627:therapeutic use / Q000633:toxicity; D051379:Mice; D010421:Pentanoic Acids / Q000494:pharmacology; D013936:Thymidine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology
D010421:Pentanoic Acids; C020524:thymidine 5'-O-pivaloate; D004247:DNA; D013936:Thymidine; D008727:Methotrexate