Effect of local anesthetics on intraocular penetration of subconjunctival antibiotics.
The combination of the subconjunctival injection of lidocaine HCl or procaine HCl with the subconjunctival injection of penicillin G, methicillin, cephaloridine, or gentamicin did not influence their intraocular penetration or subsequent antibiotic activity in aqueous humor of experimental animals.
D000779:Anesthetics, Local / Q000494:pharmacology*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis*; D001082:Aqueous Humor / Q000032:analysis* / Q000187:drug effects; D002509:Cephaloridine / Q000032:analysis; D003228:Conjunctiva; D005839:Gentamicins / Q000032:analysis; D007267:Injections; D008012:Lidocaine / Q000494:pharmacology; D008712:Methicillin / Q000032:analysis; D010400:Penicillin G / Q000032:analysis; D011343:Procaine / Q000494:pharmacology; D011817:Rabbits
D000779:Anesthetics, Local; D000900:Anti-Bacterial Agents; D005839:Gentamicins; D011343:Procaine; D008012:Lidocaine; D002509:Cephaloridine; D010400:Penicillin G; D008712:Methicillin