Meperidine does not block the cholinergic effects of oxotremorine.
Meperidine (20 and 40 mg/kg, IP) did not block the cholinergic effects (tremor, salivation, and tearing) produced by oxotremorine (0.4 mg/kg, SC) in rats, whereas atropine blocked these three effects (10 mg/kg, 2.5 mg/kg and 0.08 mg/kg, respectively.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D005260:Female; D008614:Meperidine / Q000494:pharmacology*; D010095:Oxotremorine / Q000037:antagonists & inhibitors*; D010276:Parasympatholytics; D051381:Rats; D012472:Salivation / Q000187:drug effects; D013666:Tears / Q000378:metabolism; D014202:Tremor / Q000139:chemically induced
D010276:Parasympatholytics; D010095:Oxotremorine; D001285:Atropine; D008614:Meperidine