title: [Temperature-sensitive mutants of the Venezuelan equine encephalomyelitis virus studied in the complementation test].
abstract: Investigation of 15 ts mutants of Venezuelan equine encephalomyelitis (VEE) virus by complementation tests permitted to divide these mutants into 5 complementation groups and to distinguish unclassifiable mutants. Mutants of 2 groups had RNA+/- or RNA- phenotype, i. e. had defects in RNA synthesis. Mutants in the other 3 groups had the RNA+ phenotype, and the temperature-sensitive defect of these mutants was in later stages of virus reproduction.
mesh_terms: D004666:Encephalitis Virus, Venezuelan Equine / Q000145:classification / Q000235:genetics*; D005816:Genetic Complementation Test; D009154:Mutation; D010641:Phenotype; D012367:RNA, Viral / Q000235:genetics; D013696:Temperature; D014776:Virus Cultivation
chemical_list: D012367:RNA, Viral
vernacular_title: Izuchenie temperaturochuvstvitel'nykh mutantov virusa venesuél'skogo éntsefalomielita loshadei v teste na komplementarnost'.