[Bronchodilator effect of methylxanthine derivatives (author's transl)].
The bronchodilator effect of theophylline ethylenediamine was compared with that of a combination of the methylxanthines theophylline, diprophylline and proxyphylline, after administration of slow-release capsules. At an initial dose of twice two capsules the two drug preparations produced similar, therapeutically significant, effects. When reducing the dose to twice one capsule, during long-term treatment, there was a clinically and statistically significantly greater bronchodilator effect among those patients receiving the combined methylxanthine preparation.
D000328:Adult; D000368:Aged; D001982:Bronchial Diseases / Q000188:drug therapy; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D004400:Dyphylline / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013806:Theophylline / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use*
D001993:Bronchodilator Agents; D004400:Dyphylline; D013806:Theophylline
Zur bronchodilatatorischen Wirkung von Methylxanthinderivaten.