title: [Therapy of gout].
abstract: Increasing incidence of gout and its importance as a risk factor for arteriosclerosis stimulate the practitioner to improve his knowledge about therapeutic possibilities. Therapy of gout includes (1) treatment of acute attack with colchicine and indometacin, (2) decrease of uric acid blood concentration in tophaceous gout using uricosurica, alkalinization of urin, increased diuresis, and blockade of de-novo synthesis of uric acid, and (3) maintenance therapy with allopurinol or uricosurica to avoid recurrent arthritis as well as tophi. In addition, surgical removal of larger tophi may be of benefit.
mesh_terms: D000493:Allopurinol / Q000627:therapeutic use; D001161:Arteriosclerosis / Q000209:etiology; D001553:Benzbromarone / Q000627:therapeutic use; D003078:Colchicine / Q000627:therapeutic use; D006073:Gout / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007103:Immobilization; D007213:Indomethacin; D014527:Uric Acid / Q000097:blood
chemical_list: D014527:Uric Acid; D001553:Benzbromarone; D000493:Allopurinol; D003078:Colchicine; D007213:Indomethacin
vernacular_title: Gicht-Therapie.