[Effect of the duration of the previous ischemia and of the mass of ischemic tissue on the state of the coagulating and anticoagulating blood systems in tourniquet shock].
In the experiments on 80 rabbits it was shown that the inclusion of the previously ischemized extremities into circulation is accompanied by elevation of coagulating potential of the blood and inhibition of fibrinolysis shortly after the tourniquet removal followed by hypocoagulation and fibrinolysis activation. These changes depend on the duration and mass of previously ischemized tissues. It is suggested that in tourniquet shock these disorders lead either to the danger of intravascular thrombosis or to hypocoagulation with secondary fibrinolysis.
D000818:Animals; D001777:Blood Coagulation; D005121:Extremities / Q000098:blood supply*; D005342:Fibrinolysis; D007511:Ischemia / Q000503:physiopathology*; D011817:Rabbits; D012039:Regional Blood Flow; D012769:Shock / Q000503:physiopathology*; D013997:Time Factors; D014111:Tourniquets / Q000009:adverse effects*
Vliianie dlitel'nosti predshestvuiushcheĭ ishemii i massy ishemizirovannoĭ tkani na sostoianie svertyvaiushcheĭ i protivosvertyvaiushcheĭ sistem krovi pri turniketnom shoke.