Immunological detection of somatostatin in a primitive hypothalamic mouse cell line, precursor of a neurophysin cell lineage.
A primitive nerve cell line (F7 clone), obtained by SV 40 transformation of mouse fetal hypothalamic cells, has been previously shown to share some properties with a progenitor cell for neurophysin synthesizing neuron. This paper describes the immunological detection, at the light microscope level, of somatostatin in this cell line. A SV 40 transformed neurosecretory clone, synthesizing neurophysin and vasopressin, was used as control.
D000818:Animals; D002460:Cell Line; D007031:Hypothalamus / Q000032:analysis* / Q000166:cytology; D051379:Mice; D009474:Neurons / Q000378:metabolism; D009481:Neurophysins / Q000096:biosynthesis*; D051381:Rats; D013004:Somatostatin / Q000032:analysis*; D013552:Swine
D009481:Neurophysins; D013004:Somatostatin