[The treatment of haemorrhagic complications due to disturbance of platelet function after operations with extracorporal circulation (author's transl)].
The preoperative selective blood cell separation followed by the postoperative platelet autoransfusion could prevent the exhaustion of platelet function by operations with extracorporal circulation. The postoperative blood loss could be reduced by about 57%. This method can be recommended specially in cases of increased platelet traumatization after long time perfusion. Partial disturbances of platelet function after operations with ECC can also be favourably influenced by infusion of homologous phospholipid (Fibraccel). The postoperative blood loss could be reduced by about one third. This method is beneficial in open heart surgery with short perfusion times due to its little technical expenses.
D001021:Aortic Valve; D001791:Blood Platelet Disorders / Q000209:etiology / Q000628:therapy*; D001792:Blood Platelets; D001804:Blood Transfusion, Autologous; D002469:Cell Separation / Q000379:methods; D005112:Extracorporeal Circulation / Q000009:adverse effects*; D006350:Heart Valve Prosthesis; D006801:Humans; D008943:Mitral Valve; D010977:Platelet Factor 3 / Q000627:therapeutic use
D010977:Platelet Factor 3
Therapie thrombozytärer Blutungen nach Eingriffen mit extrakorporaler Zirkulation.