Biological and phytochemical investigation of plants XV. Pteryxia terebinthina var. terebinthina (Umbelliferae).
Aqueous extracts of Pteryxia terebinthina var. terebinthina were shown to possess antiarrhythmic activity. A novel furanocoumarin, pterybinthinone, the known coumarins pteryxin and umbelliferone, and sucrose were isolated from this plant. Attempts to re-isolate a structurally undefined, defibrillatory substance by means of a published protocol were unsuccessful.
D031841:Aconitum / Q000037:antagonists & inhibitors; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000302:isolation & purification*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000188:drug therapy; D002415:Cats; D003374:Coumarins / Q000302:isolation & purification / Q000494:pharmacology; D066298:In Vitro Techniques; D010042:Ouabain / Q000037:antagonists & inhibitors; D010936:Plant Extracts / Q000494:pharmacology; D010944:Plants / Q000032:analysis*; D011817:Rabbits; D051381:Rats; D014468:Umbelliferones / Q000302:isolation & purification / Q000494:pharmacology
D000889:Anti-Arrhythmia Agents; D003374:Coumarins; D010936:Plant Extracts; D014468:Umbelliferones; C019546:pteryxin; D010042:Ouabain; C019545:pterybinthinone