The inhibitory action of glycine on rat cortical neurons.
The action of glycine (Gly) on rat cortical neurons was studied. Gly, iontophoretically applied, hyperpolarized the membrane potential, blocked the firing rate and decreased the amplitude of EPSP-IPSP sequences. Generally the membrane resistance during the aminoacid ejection decreased. The role of Gly in the rat cortical inhibition is discussed.
D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology*; D005998:Glycine / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D012964:Sodium / Q000494:pharmacology
D012964:Sodium; D005998:Glycine