Effects of neuromuscular blocking agents on arterial blood pressure in the rat.
Gallamine triethiodide pancuronium bromide or d-tubocurarine was infused intravenously at different rates in urethane anaesthetized rats. When given in neuromuscular blocking doses gallamine triethiodide produced significant hypotension if the rate of infusion exceeded 2 mg/min whereas neither pancuronium bromide nor d-tubocurarine produced a marked change in blood pressure in neuromuscular blocking doses.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D004576:Electromyography; D005703:Gallamine Triethiodide / Q000494:pharmacology; D009466:Neuromuscular Blocking Agents / Q000494:pharmacology*; D010197:Pancuronium / Q000494:pharmacology; D051381:Rats; D013997:Time Factors; D014403:Tubocurarine / Q000494:pharmacology
D009466:Neuromuscular Blocking Agents; D010197:Pancuronium; D005703:Gallamine Triethiodide; D014403:Tubocurarine