[Effect of hypothalamic electrostimulation on the 11-hydroxy-corticosteroid content in the blood and on the immunological indices in rabbits with Brown-Pearce carcinoma].
In animals with Brown--Pearce carcinoma electric stimulation of the hypothalamus makes it possible to model an increased corticosterone level in blood at early stages of the tumor growth, which conditions more active development of antitumor reactions and consequently an enhanced tumor resorption. The increased level of free corticosterone seems to be essential for "triggering" and an active mode of proceeding of antitumor immune reactions.
D015062:11-Hydroxycorticosteroids / Q000097:blood*; D000818:Animals; D002284:Carcinoma, Brown-Pearce / Q000276:immunology / Q000503:physiopathology*; D004558:Electric Stimulation; D005609:Free Radicals; D007031:Hypothalamus / Q000503:physiopathology*; D007034:Hypothalamus, Posterior / Q000503:physiopathology*; D007109:Immunity; D008213:Lymphocyte Activation; D008264:Macrophages / Q000276:immunology; D008297:Male; D009368:Neoplasm Transplantation; D011817:Rabbits; D012397:Rosette Formation; D013997:Time Factors
D015062:11-Hydroxycorticosteroids; D005609:Free Radicals
Vliianie élektrostimuliatsii gipotalamusa na soderzhanie 11-oksikortikosteroidov v krovi i immunologicheskie pokazateli u krolikov s kartsinomoĭ Brauna-Pirs.