LOGIT: a program for dose-response analysis.
We describe a FORTRAN computer program for fitting the logistic distribution function: (formula: see text) Where x represents dose or time, to dose-response data. The program determines both weighted least squares and maximum likelihood estimates for the parameters alpha and beta. It also calculates the standard errors of alpha and beta under both estimation methods, as well as the median lethal dose (LD50) and its standard error. Dose--response curves found by both fitting methods can be plotted as well as the 95% confidence bands for these lines.
D003201:Computers; D004305:Dose-Response Relationship, Drug; D007928:Lethal Dose 50; D008954:Models, Biological; D012044:Regression Analysis