Inhibitory effect of quinidine on catecholamine release from adrenal medulla.
Quinidine was found to inhibit catecholamine release from the medulla of perfused adrenal glands induced by carbamylcholine. It also inhibited the release of catecholamine from adrenomedullary granules induced by ATP-Mg++.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000313:Adrenal Medulla / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D002217:Carbachol / Q000494:pharmacology; D002395:Catecholamines / Q000378:metabolism*; D002417:Cattle; D002837:Chromaffin Granules / Q000378:metabolism; D003864:Depression, Chemical; D004347:Drug Interactions; D066298:In Vitro Techniques; D011802:Quinidine / Q000494:pharmacology*; D013997:Time Factors
D002395:Catecholamines; D000255:Adenosine Triphosphate; D002217:Carbachol; D011802:Quinidine