Damage to Trichinella spiralis newborn larvae by eosinophil major basic protein.
Purified eosinophil major basic protein damaged newborn larvae of Trichinella siralis when added to in vitro cultures. Damaged larvae were stiffened, immobile, and showed a granular appearance by light microscopy. Larvae in control cultures and in cultures containing equimolar concentrations of other basic proteins failed to exhibit such damage.
D000818:Animals; D001798:Blood Proteins / Q000494:pharmacology*; D002478:Cells, Cultured; D004804:Eosinophils; D066298:In Vitro Techniques; D007814:Larva; D014234:Trichinella / Q000187:drug effects*
D001798:Blood Proteins