title: Synthesis and biological activity evaluation of some quinolines.
abstract: Synthesis of some quinolines having the thiosemicarbazide and nitrostyryl moieties is described. 8-nitroquinoline-4-acraldehyde undergoes Vilsmeier reaction with dimethylacetamide to afford the respective pentadiene amide. Screening of the synthesized quinolines for bactericidal and mollusicidal activities is reported.
mesh_terms: D000818:Animals; D007928:Lethal Dose 50; D009603:Nitroso Compounds / Q000138:chemical synthesis; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D012485:Salmonella typhi / Q000187:drug effects; D012908:Snails / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013882:Thiosemicarbazones / Q000138:chemical synthesis
chemical_list: D009603:Nitroso Compounds; D011804:Quinolines; D013882:Thiosemicarbazones