[Sodium transport and potassium excretion by the salivary ducts of the dog's submandibular gland (author's transl)].
In order to study the possibility of the existence of a threshold for the transport capacity for sodium by the salivary ducts of the dog's submandibular gland 10 mongrel dogs were rendered hypernatremic by the intravenous infusion of a hypertonic sodium solution. The main excretory duct was canulated and the vegetative branch of the chorda tympani nerve was maximally excited for 20-minute periods intercalated by similar periods of rest. A threshold for sodium transport was observed, dependent on the amount of sodium offered to the salivary ducts and on the salivary flow. This threshold is around 75 uEq/min with a flow of saliva of 1.3 ml per minute. The excretion of potassium in these experiments did not show a trend to reach a threshold.
D000818:Animals; D001692:Biological Transport; D002463:Cell Membrane Permeability; D002814:Chorda Tympani Nerve / Q000502:physiology; D004285:Dogs; D004558:Electric Stimulation; D006955:Hypernatremia / Q000139:chemically induced; D011188:Potassium / Q000378:metabolism*; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage; D012463:Saliva / Q000032:analysis* / Q000378:metabolism; D012964:Sodium / Q000097:blood / Q000378:metabolism*; D013363:Submandibular Gland / Q000378:metabolism*
D012462:Saline Solution, Hypertonic; D012964:Sodium; D011188:Potassium
Transporte de sódio e excreção de potássio pelos ductos salivares da glândula submandibular do cão.