title: Premature rupture of the membranes: a conservative approach.
abstract: A conservative approach was followed in 188 patients with premature rupture of the membranes (PROM) over a 2 year period. There were no neonatal deaths from sepsis, and only one infant showed a positive central bacteriologic culture. Fifty-seven percent of all patients less than 37 weeks' gestation had a latent period of 24 hours and 19% went beyond 7 days before labor began. Patients less than 34 weeks' gestation who received antepartum steroids for lung maturation showed no increased infectious morbidity or mortality. A conservative approach to patients with PROM seems reasonable when either prematurity and/or a cervix unfavorable for induction further complicates the pregnancy.
mesh_terms: D036861:Delivery, Obstetric; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000175:diagnosis / Q000628:therapy*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000517:prevention & control; D007751:Labor, Induced; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012127:Respiratory Distress Syndrome, Newborn / Q000517:prevention & control; D012306:Risk; D018805:Sepsis / Q000150:complications; D013256:Steroids / Q000627:therapeutic use
chemical_list: D013256:Steroids