Visual loss and foveal lesions in Usher's syndrome.
Forty-eight patients with Usher's syndrome were assess for the degree of visual loss, extent of lens opacities, and presence of foveal lesions. Twenty-one patients (44%) showed either atrophic or cystic-appearing bilateral foveal changes. Despite having foveal lesions and variable degrees of lens opacities most patients maintained central visual acuity of 20/60 or better until their middle 30s.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002386:Cataract / Q000473:pathology; D002648:Child; D005260:Female; D005584:Fovea Centralis / Q000473:pathology*; D006319:Hearing Loss, Sensorineural / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D007908:Lens, Crystalline / Q000473:pathology; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012174:Retinitis Pigmentosa / Q000473:pathology* / Q000503:physiopathology; D013577:Syndrome; D014786:Vision Disorders / Q000473:pathology* / Q000503:physiopathology; D014792:Visual Acuity