title: [Occurrence of congenital ocular toxoplasmosis in siblings].
abstract: The author points out in connection with the description of two families in which evidently several children suffered damage through toxoplasmosis with which the mother had been infected a long time ago (pseudocoloboma of the macula, changes of the macula similar to juvenile degreneration, abortion and malformations such as anophthalmia, rhinoschisis, cheiloschisis, gnathoschisis and palatoschisis), that low titer levels in the Sabin-Feldmann test and in the complement fixation test are by no means totally insignificant for subsequent pregnancies, as is commonly assumed. In any case, women who have already given birth to children with congenital toxoplasmosis should be subjected to toxoplasmosis treatment, as far as possible, before any new pregnancy.
mesh_terms: D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis; D012698:Serologic Tests; D014123:Toxoplasmosis / Q000175:diagnosis; D014126:Toxoplasmosis, Ocular / Q000151:congenital / Q000235:genetics*
vernacular_title: Zur Frage des Vorkommens angeborener toxoplasmogener Augenveränderungen bei Geschwistern.