[Paraneoplastic hypercalcaemia in a case of carcinoma of the bladder. Demonstration in the tumour of a substance with parathormone activity (author's transl)].
Hypercalcaemia accompanied a bladder tumour in a 77-year-old woman. Immuno-reactive parathormone (IPTH) in the tumour being high, the hypercalcaemia could thus be attributed to secretion by the tumour of a substance with parathormone activity. The rarity of bladder tumours at the origin of paraneoplastic hypercalcaemia is recalled. The mechanism of the metabolic disturbance and the disagreement between serum and tumour levels of IPTH are discussed.
D000368:Aged; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D010281:Parathyroid Hormone / Q000032:analysis / Q000378:metabolism*; D001749:Urinary Bladder Neoplasms / Q000032:analysis / Q000150:complications* / Q000378:metabolism
D010281:Parathyroid Hormone
Hypercalcémie paranéoplasique au cours d'un cancer de la vessie. Mise en évidence dans la tumeur d'une substance à activité parathormone.