[Use of carminomycin in combination with UHF hyperthermia in the therapy of sarcoma 180].
It was found that combined treatment of sarcoma 180 with local U. H. F.-hyperthermia and carminomycin resulted in the tumor growth inhibition by more than 90 per cent, which was much higher than the effect of every agent alone. The thermochemotherapy allowed a decrease in the dose of the antibiotic without decreasing the antitumor effect. The U. H. F.-hyperthermia has an independent tumorolytic effect and promotes selective accumulation of carminomycin by the tumor.
D000818:Animals; D002360:Carubicin / Q000627:therapeutic use*; D003630:Daunorubicin / Q000031:analogs & derivatives*; D004353:Drug Evaluation, Preclinical; D055590:Electromagnetic Phenomena / Q000627:therapeutic use*; D006979:Hyperthermia, Induced / Q000379:methods*; D051379:Mice; D008808:Mice, Inbred CBA; D009368:Neoplasm Transplantation; D012510:Sarcoma 180 / Q000628:therapy*
D002360:Carubicin; D003630:Daunorubicin
Primenenie karminomitsina v sochetanii s UVCh-gipertermieĭ v terapii sarkomy 180.