Radioprotective effect of a protein free parathyroid extract on the mitotic index of rat bone marrow cells.
The protective efficacy of an orally administered bovine protein-free parathyroid extract (PF-PTE) was studied on rat bone marrow cells in vivo with the mitotic index after 850 R irradiation. A remarkable decrease was found in the mitotic activity of bone marrow cells after irradiation in the non-protected animals. However, in the animals treated with PF-PTE after irradiation, a significantly smaller decrease and a faster recovery were found in the mitotic activity of the bone marrow cells.
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000502:physiology / Q000528:radiation effects*; D002417:Cattle; D008938:Mitosis / Q000528:radiation effects*; D008940:Mitotic Index / Q000187:drug effects / Q000528:radiation effects*; D010280:Parathyroid Glands / Q000502:physiology*; D011837:Radiation-Protective Agents; D051381:Rats; D014020:Tissue Extracts / Q000494:pharmacology*
D011837:Radiation-Protective Agents; D014020:Tissue Extracts