Mitotic spindle fiber orientation in relation to cell migration in the neo-cortex of normal and reeler mouse.
The angular distribution of mitotic spindle fibers has been studied in the telencephalic ventricular zone (VZ) of mouse embryos and has been found to be monophasic and invariant during the early cortical histogenesis both in the normal and in a reeler embryo. This observation suggests that the orientation of mitotic spindle fibers is independent of nerve cell migration in the embryonic cortex.
D000818:Animals; D002465:Cell Movement; D002540:Cerebral Cortex / Q000196:embryology*; D051379:Mice; D008818:Mice, Neurologic Mutants / Q000196:embryology; D008938:Mitosis