Basal cell nevus syndrome and adenocarcinoma of the colon. Response to systemic fluorouracil.
A patient with basal nervus syndrome was found to have an adenocarcinoma of the colon. This association, probably fortuitous, made it possible to study the effect of intravenous 5-fluorouracil on the cutaneous basal cell tumors. There was no reaction to this treatment. Subsequently, all visible basal cell tumors were satisfactorily eradicated with topical 5-fluorouracil.
D000230:Adenocarcinoma / Q000150:complications / Q000188:drug therapy*; D000328:Adult; D002280:Basal Cell Carcinoma / Q000150:complications / Q000188:drug therapy*; D003110:Colonic Neoplasms / Q000150:complications / Q000188:drug therapy*; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use*; D006801:Humans; D009506:Nevus / Q000150:complications / Q000188:drug therapy*; D012878:Skin Neoplasms / Q000150:complications / Q000188:drug therapy*; D013577:Syndrome
D005472:Fluorouracil