title: On a mechanism for the mood and personality changes of adult and later life. A psychobiological hypothesis.
mesh_terms: D000339:Affect / Q000187:drug effects / Q000502:physiology; D000375:Aging / Q000187:drug effects; D000818:Animals; D000929:Antidepressive Agents, Tricyclic / Q000494:pharmacology; D001714:Bipolar Disorder / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D002997:Clomipramine / Q000494:pharmacology; D004292:Dominance, Cerebral / Q000187:drug effects / Q000502:physiology; D004298:Dopamine / Q000378:metabolism; D004833:Epilepsy, Temporal Lobe / Q000378:metabolism; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D008094:Lithium / Q000494:pharmacology; D008959:Models, Neurological; D009433:Neural Inhibition / Q000187:drug effects; D009638:Norepinephrine / Q000378:metabolism; D010551:Personality / Q000187:drug effects; D010554:Personality Disorders / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism
chemical_list: D000929:Antidepressive Agents, Tricyclic; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D008094:Lithium; D002997:Clomipramine; D004298:Dopamine; D009638:Norepinephrine