title: Damage to Trichinella spiralis newborn larvae by eosinophil major basic protein.
abstract: Purified eosinophil major basic protein damaged newborn larvae of Trichinella siralis when added to in vitro cultures. Damaged larvae were stiffened, immobile, and showed a granular appearance by light microscopy. Larvae in control cultures and in cultures containing equimolar concentrations of other basic proteins failed to exhibit such damage.
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000494:pharmacology*; D002478:Cells, Cultured; D004804:Eosinophils; D066298:In Vitro Techniques; D007814:Larva; D014234:Trichinella / Q000187:drug effects*
chemical_list: D001798:Blood Proteins