[Behavior of plasma androgens in cases of adrenal pathology].
Following chromatographic separation, the RI method has been used to examine the behaviour of plasmatic androgens in a group of normal subjects, in two patients with Addison's disease and two patients with hypercorticoadrenalism, due respectively to corticoadrenal adenoma and bilateral adenomatous hyperplasia. A significant reduction in adrenal androgens was observed in patients suffering from Addison's disease. The most interesting information, however, was the paradoxical reduction in DHEA and delta 4-A in patients with corticoadrenal hyperfunction.
D015062:11-Hydroxycorticosteroids / Q000097:blood; D015068:17-Ketosteroids / Q000097:blood; D000224:Addison Disease / Q000503:physiopathology; D000236:Adenoma / Q000503:physiopathology; D000305:Adrenal Cortex Hormones / Q000097:blood*; D000307:Adrenal Gland Diseases / Q000503:physiopathology*; D000310:Adrenal Gland Neoplasms / Q000503:physiopathology; D000328:Adult; D000728:Androgens / Q000097:blood*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006965:Hyperplasia
D015062:11-Hydroxycorticosteroids; D015068:17-Ketosteroids; D000305:Adrenal Cortex Hormones; D000728:Androgens; D006854:Hydrocortisone
Comportamento degli androgeni plasmatici in alcuni casi di patologia surrenaliea.