[Effect of an autovaccine on the course of an experimental staphylococcal infection].
The effect of autovaccine on the state of cellular immunity in mice with staphylococcal infection was studied. The maximum decrease of staphylococcal dissemination in internal organs, espeically in the lungs, as well as an increase in the intensity of phagocytosis by peritoneal macrophages were observed after the administration of the vaccine by the method of inhalation. The intranasal administration of the vaccine also proved to be more effective than subcutaneous injection. The cumulation of immune response was more pronounced after the aerosol administration of autovaccine, especially in cases of pathological processes in the respiratory organs.
D000818:Animals; D004353:Drug Evaluation, Preclinical; D005260:Female; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D010587:Phagocytosis / Q000187:drug effects; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013209:Staphylococcal Vaccines / Q000008:administration & dosage*; D013997:Time Factors
D013209:Staphylococcal Vaccines
Vliianie autovaktsiny na techenie éksperimental'noĭ stafilokokkovoĭ infektsii.