Recognition mechanisms in infectious disease.
Recent studies have begun to elucidate the nature of pathogen-host recognition mechanisms. Not only is our understanding of the nature of infection thereby growing, but there is promise of an entirely new approach to treatment--by inhibiting or preventing the contact between pathogen and target cell, the first step in the infectious process. Models have largely been elucidated for shigella infections and cholera.
D001424:Bacterial Infections / Q000473:pathology; D002771:Cholera / Q000382:microbiology; D004405:Dysentery, Bacillary / Q000382:microbiology; D006801:Humans; D007239:Infections / Q000382:microbiology / Q000473:pathology*; D008954:Models, Biological; D013812:Therapeutics