title: Biochemical characterization of the proliferation pool of lymphatic cells in the human tonsil and demonstration of the age-dependent pool size reduction.
abstract: The DNA and RNA content and also the thymidine and uridine incorporation kinetics were determined in peripheral lymphocytes and lymphatic cells of the tonsil. The existence of a proliferation pool of lymphoid cells in the tonsil could be established by the comparison of all data. An age-conditioned reduction of the pool size was assumed from the uridine incorporation rate which takes place faster than the organo-specific cell decrease likewise conditioned by age in the tonsil. The abscess tonsil could be explained as a pathological state with considerable reduction of proliferation.
mesh_terms: D000328:Adult; D000367:Age Factors; D002455:Cell Division; D002648:Child; D002675:Child, Preschool; D004247:DNA / Q000096:biosynthesis / Q000378:metabolism; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes / Q000378:metabolism*; D014066:Palatine Tonsil / Q000166:cytology* / Q000378:metabolism; D012313:RNA / Q000096:biosynthesis / Q000378:metabolism; D013936:Thymidine / Q000378:metabolism; D014529:Uridine / Q000378:metabolism
chemical_list: D012313:RNA; D004247:DNA; D013936:Thymidine; D014529:Uridine