title: [Effects of venous compression for blood sampling on the results of in vitro tests of thyroid function (author's transl)].
abstract: In a group of subjects with a normal as well as pathological thyroid function there was a significant increase in RT3U, serum-thyroxine-concentrations and TSH-levels but there were no significant changes in the T4-RT3U-indices and ETR-tests after 5 min of venous compression. The discordant results were obtained in 21 cases (26.9%) with the RT3U-test and in 4 cases (5,1%) with the T4-serum-level-determination, which may cause diagnostic errors. The non-standardized venous compression time causes a widening of the euthyroid zone which reduces the discrimination capabilities of these function tests. With TSH-determinations these deviations may be of diagnostic importance in the evaluation of TRH-TSH-test results. A standardized and minimum compression time when drawing blood samples is recommended in order to eliminate this potential source of diagnostic error.
mesh_terms: D001132:Arm / Q000098:blood supply; D001800:Blood Specimen Collection / Q000379:methods*; D006801:Humans; D011312:Pressure; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood; D014680:Veins
chemical_list: D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine
vernacular_title: Einfluss der Venenkompression bei der Blutentnahme auf die Ergebnisse der in vitro-Teste der Schilddrüsenfunktion.