[Salmonella-meningitis in the newborn (author's transl)].
Six children, out of twelve in a neonatal unit suffered from group D salmonellosis. Two patients presented in addition to intestinal manifestations massive extraintestinal symptoms, both with septicemia and meningitis. One patient died on the fourth day from massive disseminated intravascular coagulation and pyocephalus. The other patient had a complete recovery after an antibiotic therapy with chloramphenicol and ampicillin. As the source of infection the mother of case 1 was identified. In her stools salmonella group D were cultured. Cultures of the ward-personals, stool and the food were negative. It should be mentioned that only children fed with artificial food suffered from salmonellosis; whereas children on breastmilk had an unremarkable clinical course and consistantly negative stoolcultures.
D000667:Ampicillin / Q000627:therapeutic use; D001942:Breast Feeding; D002701:Chloramphenicol / Q000627:therapeutic use; D003428:Cross Infection; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000382:microbiology; D008581:Meningitis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D012480:Salmonella Infections / Q000150:complications* / Q000188:drug therapy; D018805:Sepsis / Q000209:etiology
D002701:Chloramphenicol; D000667:Ampicillin
Salmonella-Meningitis im Neugeborenenalter. Eine Kleinepidemie im Neugeborenenzimmer einer geburtshilflichen Abteilung.