title: Sinus node disease affecting both parents and both children.
abstract: A family is described in which both parents and both of their children developed conducting system disease before the age of 40. They all had evidence of possible sinus node dysfunction. The father and son had an unexplained polyneuritis during childhood.
mesh_terms: D000293:Adolescent; D000328:Adult; D001146:Arrhythmia, Sinus / Q000150:complications / Q000175:diagnosis / Q000235:genetics*; D001282:Atrial Flutter / Q000175:diagnosis; D001919:Bradycardia / Q000175:diagnosis; D002648:Child; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011115:Polyneuropathies / Q000150:complications; D012848:Sinoatrial Block / Q000175:diagnosis; D013577:Syndrome; D013610:Tachycardia / Q000175:diagnosis