Effect of prostaglandin F-2 alpha on ovarian enzyme activity in the hysterectomized guinea-pig.
The enzymes studied were cholesterol esterase, cholesterol ester synthetase 3 beta-hydroxysteroid dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase. PGF-2 alpha reduced the activities of 3 beta-hydroxysteroid dehydrogenase and cholesterol esterase but did not affect those of cholesterol ester synthetase of 20 alpha-hydroxysteroid dehydrogenase.
D015089:20-Hydroxysteroid Dehydrogenases / Q000378:metabolism; D015096:3-Hydroxysteroid Dehydrogenases / Q000378:metabolism; D000818:Animals; D005260:Female; D006168:Guinea Pigs; D007044:Hysterectomy; D010053:Ovary / Q000187:drug effects / Q000201:enzymology*; D011460:Prostaglandins F / Q000494:pharmacology*; D002787:Sterol Esterase / Q000378:metabolism; D002785:Sterol O-Acyltransferase / Q000378:metabolism
D011460:Prostaglandins F; D015096:3-Hydroxysteroid Dehydrogenases; D015089:20-Hydroxysteroid Dehydrogenases; D002785:Sterol O-Acyltransferase; D002787:Sterol Esterase