Hypersensitivity to isoproterenol in rabbit heart decreases guanine nucleotide effect on adenylate cyclase.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000526:Alprenolol / Q000031:analogs & derivatives / Q000378:metabolism; D000818:Animals; D002462:Cell Membrane / Q000201:enzymology; D006150:Guanine Nucleotides / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects*; D066298:In Vitro Techniques; D007545:Isoproterenol / Q000494:pharmacology*; D009206:Myocardium / Q000201:enzymology; D011817:Rabbits; D012110:Reserpine / Q000494:pharmacology
D006150:Guanine Nucleotides; D000526:Alprenolol; D012110:Reserpine; D000262:Adenylyl Cyclases; D007545:Isoproterenol