Intracranial germinomas: treatment and results.
Eighty-nine patients with intracranial germinomas were treated from 1954 through 1975. Radiotherapy was given in 62 patients. The five-year survival rate was 61% and the ten-year survival rate was 55%. In unbiopsied patients the five-year survival rate was 66% and the ten-year survival rate was 59%, whereas in biopsied ones it was 56% and 47%, respectively. Prophylactic irradiation to the spinal axis in the presence of germinoma cells in the cerebrospinal fluid may not be justified.
D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D004407:Dysgerminoma / Q000532:radiotherapy / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies