title: [Tryptamine metabolic study in man].
abstract: A modified norharmane method was used for estimation of tryptamine in human urine at normal state. Tryptamine excretion did not depend on diuresis. Administration of neomycin did not affect the tryptamine excretion, which is inconsistent with the hypothesis on bacterial origin of the amine. Dynamics of tryptamine excretion was studied after administration of tryptophane, inhibitors of monoamine oxidase and their combinations. Sydnophen and sydnocarb caused hypotryptaminuria. Marked hypertryptaminuria was observed in severe chronic hepatitis and liver cirrhosis.
mesh_terms: D000293:Adolescent; D000328:Adult; D002940:Circadian Rhythm; D004231:Diuresis / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007668:Kidney / Q000502:physiology; D008107:Liver Diseases / Q000652:urine; D008297:Male; D008875:Middle Aged; D008996:Monoamine Oxidase Inhibitors; D009355:Neomycin; D011619:Psychotropic Drugs; D012016:Reference Values; D013558:Sydnones; D013997:Time Factors; D014363:Tryptamines / Q000652:urine*; D014364:Tryptophan
chemical_list: D008996:Monoamine Oxidase Inhibitors; D011619:Psychotropic Drugs; D013558:Sydnones; D014363:Tryptamines; D014364:Tryptophan; D009355:Neomycin
vernacular_title: Issledovanie obmena triptamina u cheloveka.