Antifertility efficacy of the plant Aristolochia indica linn on mouse.
Two compounds isolated from the alcoholic extract of the roots of Aristolochia indica Linn were tested on day 6 pregnant mice. One of the compounds, p-coumaric acid showed 100% interceptive activity at the single oral dose of 50 mg/kg of body weight. The antifertility efficacy of these two compounds is discussed.
D000818:Animals; D003338:Corpus Luteum / Q000473:pathology; D003373:Coumaric Acids / Q000494:pharmacology; D010064:Embryo Implantation; D005260:Female; D005298:Fertility / Q000187:drug effects*; D005960:Glucosides / Q000494:pharmacology; D008297:Male; D051379:Mice; D010053:Ovary / Q000473:pathology; D010944:Plants; D011247:Pregnancy
D003373:Coumaric Acids; D005960:Glucosides