Prolonged manometric study of the gastroduodenal junction in man.
A study of the motor activity of the gastroduodenal (GD) junction has been carried out on 8 subjects by using an original probe provided with a suction cup, that allows not only a duodenogastric (DG) pull-though, but also a prolonged recording of the pyloric, antral and duodenal motor activity, in basal condition and after intraduodenal instillation of HCl 0.1 N and intravenous infusion of cerulein. The position of the probe was controlled with fluoroscopy and transmural potential difference. The DG pull-through did not show a zone of high pressure at the GD junction, but the prolonged study showed, during HC1 and cerulein administrations, a significant increase of the pyloric tonus.
D000328:Adult; D002569:Cerulenin / Q000494:pharmacology; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D006851:Hydrochloric Acid / Q000494:pharmacology; D008297:Male; D008365:Manometry; D008875:Middle Aged; D011706:Pyloric Antrum / Q000502:physiology; D011708:Pylorus / Q000502:physiology*; D012462:Saline Solution, Hypertonic / Q000494:pharmacology; D013997:Time Factors
D012462:Saline Solution, Hypertonic; D002569:Cerulenin; D006851:Hydrochloric Acid