Becker's melanosis: an ultrastructural study.
Becker's melanosis is an uncommon condition characterized by hypertrichosis, hyperpigmentation of the epidermis, dermal melanophages and absence of nevus cells. Ultrastructural examination of such a melanotic lesion from a young white man revealed giant melanosomes. In addition, normal-sized melanosomes were found singly in the keratinocytes of the involved skin. Dermal venules were surrounded by multiple layers of basement membrane.
D000328:Adult; D006801:Humans; D006983:Hypertrichosis / Q000473:pathology; D008297:Male; D008544:Melanocytes / Q000648:ultrastructure; D008548:Melanosis / Q000473:pathology*; D008854:Microscopy, Electron; D009940:Organoids / Q000648:ultrastructure; D012867:Skin / Q000648:ultrastructure*; D013577:Syndrome