[Abnormal movements induced by psychotropic drugs].
The abnormal movements produced by the psychotropic drugs are related to various physiopathological mechanisms: -- dopaminergic receptors blockage provokes neuroleptic parkinsoniam tremor; -- neuroleptic-induced tardive dyskinesia is similar to 1. Dopa abnormal movements; tardive dyskinesia is due to denervation induced hypersensitivity of the dopamine receptor; the 1. Dopa dyskinesia is probably related to altered responsiveness of these receptors due to an increase in dopaminergic receptor sensitivity; -- antidepressant drugs, particularly lithium, provoke tremor, alleviated by beta blockage; it is probably caused by an abnormal sensitivity of the beta noradrenergic receptors.
D002819:Chorea / Q000139:chemically induced; D004409:Dyskinesia, Drug-Induced / Q000209:etiology*; D006801:Humans; D007980:Levodopa / Q000009:adverse effects; D008094:Lithium / Q000009:adverse effects; D009069:Movement Disorders / Q000139:chemically induced* / Q000503:physiopathology; D010302:Parkinson Disease, Secondary / Q000139:chemically induced; D011619:Psychotropic Drugs / Q000009:adverse effects*; D011954:Receptors, Dopamine / Q000187:drug effects; D011955:Receptors, Drug / Q000187:drug effects; D014202:Tremor / Q000139:chemically induced*
D011619:Psychotropic Drugs; D011954:Receptors, Dopamine; D011955:Receptors, Drug; D007980:Levodopa; D008094:Lithium
Mouvements anormaux induits par les médicaments psychotropes.