A krypton-81m generator for organ ventilation and perfusion investigations.
A sterile pyrogen-free generator for ultra-short half-life 81mKr has been developed. During initial loading, the binding efficiency of 81Rb is 90--99%. The count rate during perfusion is 3 x 10(5) counts per minute for a 1,9 GBq (50 mCi) 81Rb generator. The generator has been used for routine and special investigations of lung perfusion and ventilation and for myocardial perfusion during catheterization.
D006321:Heart; D006801:Humans; D007726:Krypton; D008168:Lung / Q000502:physiology; D010477:Perfusion; D011868:Radioisotopes; D011876:Radionuclide Generators / Q000295:instrumentation*; D012119:Respiration; D012413:Rubidium / Q000032:analysis
D011868:Radioisotopes; D007726:Krypton; D012413:Rubidium