title: Hepatic necrosis caused by halothane and hypoxia in phenobarbital-treated rats.
mesh_terms: D000769:Anesthesia, Inhalation; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology / Q000473:pathology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004790:Enzyme Induction; D005459:Fluorides / Q000097:blood; D005978:Glutathione / Q000378:metabolism; D006221:Halothane / Q000008:administration & dosage / Q000633:toxicity*; D000860:Hypoxia / Q000150:complications* / Q000201:enzymology / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D009336:Necrosis; D010634:Phenobarbital / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats
chemical_list: D003577:Cytochrome P-450 Enzyme System; D005978:Glutathione; D005459:Fluorides; D006221:Halothane; D010634:Phenobarbital