title: Normal versus alpha-amanitin induced cellular dynamics of the midgut epithelium in female Aedes aegypti L. (Insecta, Diptera) in response to blood feeding.
abstract: In midgut epithelial cells (stomach) of untreated female A. aegypti an increase in the surface area of the rough endoplasmic reticulum (rer) and in the ratio of membrane-bound to free ribosomes is morphometrically measured during digestion of the first blood meal. This can be correlated with the synthesis and release of digestive proteases. The dynamics of the ribosomes in A. aegypti are similar to those in A. stephensi. 3 ng alpha-amanitin per mosquito prevent normal blood digestion, the proliferation of the rer and the increase in the ratio of bound to free ribosomes. On the other hand, some synthesis of new ribosomes takes place.
mesh_terms: D000330:Aedes / Q000502:physiology* / Q000648:ultrastructure; D000546:Amanitins / Q000494:pharmacology; D000818:Animals; D001769:Blood; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D004063:Digestion; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D012270:Ribosomes / Q000648:ultrastructure; D013270:Stomach / Q000648:ultrastructure
chemical_list: D000546:Amanitins