[Pathology of mitosis after cellular recovery from a metaphase block].
The experiments in Chinese hamster fibroblast-like cells have shown that the c-mitosis inducing agents (colchicine, colcemid and low temperature) produce evident stathmokinetic and radiomimetic effects. By the reversibility moment of the former the latter becomes apparent, manifesting in bridge accumulation. This form of pathology is likely to be caused by the disturbance of the cellular nucleoprotein metabolism in c-mitosis.
D000818:Animals; D002453:Cell Cycle / Q000187:drug effects; D002478:Cells, Cultured; D003078:Colchicine / Q000494:pharmacology; D003080:Cold Temperature; D006224:Cricetinae; D003412:Cricetulus; D003703:Demecolcine / Q000494:pharmacology; D066298:In Vitro Techniques; D007700:Kinetics; D008677:Metaphase / Q000187:drug effects; D008938:Mitosis / Q000187:drug effects; D013997:Time Factors
D003078:Colchicine; D003703:Demecolcine
Patologiia mitoza posle vykhoda kletok iz metafaznogo bloka.