title: The fate of adenosine monophosphate in the rat after a single oral administration. Influence of a simultaneous treatment by papaverine.
abstract: The fate in the organism of Adenosine Monophosphate after a single oral administration of 10 mg/kg, was studied in the Rat, using 14C-labelled AMP. This paper deals more specially with the study of the plasmatic kinetics of AMP, since we proved at first that the AMP molecule goes intact through the intestinal barrier into the blood. The effects on these kinetics of a joint administration of Papaverine are considered.
mesh_terms: D000249:Adenosine Monophosphate / Q000097:blood / Q000378:metabolism* / Q000652:urine; D000818:Animals; D004347:Drug Interactions; D005243:Feces / Q000032:analysis; D005260:Female; D007700:Kinetics; D008297:Male; D010208:Papaverine / Q000494:pharmacology*; D051381:Rats
chemical_list: D000249:Adenosine Monophosphate; D010208:Papaverine