Selectivity and rejectivity in cancer metastasis.
In cancer metastasis, "selectivity" denotes the formation of secondary tumor in an organ in such a manner that its localization pattern is peculiar. The opposite phenomenon should be recognized and called "rejectivity". In man, carcinomas appear to spread selectively to the umbilicus, whereas lymphomas seem to reject that site. In all probability, recognition of the twin theory of selectivity and rejectivity will stimulate research on cancer dissemination.
D006801:Humans; D008223:Lymphoma / Q000473:pathology; D009362:Neoplasm Metastasis / Q000503:physiopathology*; D009928:Organ Specificity; D014472:Umbilicus / Q000503:physiopathology