[The haemodynamic principle of action of diazoxide (hypertonalum) in the treatment of acute hypertensive crises in late pregnant women (author's transl)].
In ten hypertensive late pregnant women with passing crises of hypertension cardiovascular analysis with the method of quantitative sphygmometry, the unbloody recording of the blood pressure and the direct electronic measuring of the pulse wave velocity were made before and after the intravenous injection of 300 mg Diazoxid (Hypertonalum). This drug is recommended to the treatment of severe preeclampsia and eclampsia because of lessening the arterial blood pressure and the total peripheral resistance, increasing the heart rate, stroke volume and cardiac output.
D000208:Acute Disease; D002302:Cardiac Output / Q000187:drug effects; D003981:Diazoxide / Q000494:pharmacology / Q000627:therapeutic use*; D004461:Eclampsia / Q000188:drug therapy; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*; D011674:Pulse / Q000187:drug effects; D014655:Vascular Resistance / Q000187:drug effects
D003981:Diazoxide
Das hämodynamische Wirkungsprinzip von Diazoxid (Hypertonalum) bei der Behandlung akuter Hochdruckkrisen in graviditate.