title: [Possibilities of radiation-dose reduction in the treatment of Hodgkin's disease. I. Exclusion of the mediastinum from the radiation field in primary high-cervical or infradiaphragmatic involvement and stage I or II (author's transl)].
abstract: A retrospective analysis on 482 patients with localised Hodgkin's disease revealed that none of those with primary high-cervical or primary infradiaphragmatic involvement had any infiltration of the mediastinum, either at the time or later. As a result, prophylactic mediastinal radiation was not practised if high-cervical or infradiaphragmatic lymph-nodes had been affected first. None of these patients had any mediastinal recurrence after at least seven years.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D003964:Diaphragm; D005500:Follow-Up Studies; D006689:Hodgkin Disease / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008479:Mediastinal Neoplasms / Q000532:radiotherapy; D008875:Middle Aged; D009333:Neck
vernacular_title: Möglichkeiten einer Therapiereduktion beim Morbus Hodgkin. I. Aussparung des Mediastinums aus dem Strahlenfeld bei primär hochzervikalem oder infradiaphragmalem Befall und Stadium I oder II.