title: Induction of parturition in the sow with a prostaglandin analogue (I.C.I. 80996).
abstract: Parturition was induced in 112 gilts and sows on day 111,, 112, and 113 of gestation by means of a single intramuscular injection of 175 mcg of a prostaglandin F2 alpha analogue (Cloprostenol, I.C.I 80996). No side effects were detected immediately after injection and the course of the induced parturition was normal. The interval between injection and parturition was approximately 28 hours. Induction of parturition on day 113 resulted in a significant shortening of this interval as compared with day 111, and 112. The average weights of the piglets at birth and at 5 weeks were within the normal range. The percentage of stillbirths and the loss of piglets up to weaning did not differ significantly between control and experimental groups. The practical applications of induction of parturition are discussed.
mesh_terms: D000818:Animals; D001724:Birth Weight; D003008:Cloprostenol / Q000009:adverse effects / Q000494:pharmacology; D005260:Female; D007751:Labor, Induced / Q000379:methods / Q000662:veterinary*; D008098:Litter Size / Q000187:drug effects; D011247:Pregnancy; D011461:Prostaglandins F, Synthetic / Q000009:adverse effects / Q000494:pharmacology; D013552:Swine
chemical_list: D011461:Prostaglandins F, Synthetic; D003008:Cloprostenol