Can elevated levels of copper in drinking water precipitate aucte hemolysis in G-6-PD deficient individuals?
The hypothesis that elevated levels of copper in drinking water may be a factor in the precipitation of acute hemolysis in those with a G-6-PD deficiency in their erythrocytes is developed. The present U.S. EPA drinking water standards do not have a primary (or human health) standard for copper but only a secondary standard which is designed to prevent an unacceptable taste. Because of the widespread occurrence of elevated levels of copper in drinking water in areas where the water is corrosive and the households have copper piping, it is recommended that environmental health regulatory agencies develop a risk assessment concerning the effects of copper on those high risk groups who are predisposed to develop a copper induced hemolysis.
D003300:Copper / Q000009:adverse effects*; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood* / Q000150:complications; D006461:Hemolysis; D006801:Humans; D012306:Risk; D014881:Water Supply / Q000032:analysis*
D003300:Copper