title: Antineoplastic activity and cytotoxicity of flavones, isoflavones, and flavanones.
abstract: Several hundred flavonoid derivatives, natural and synthetic, which have been tested in the screening program of the National Cancer Institute, have been examined for indications of structure-activity relationships which might exist among these compounds. No such relationships are apparent. In spite of occasional activity these compounds do not warrant further detailed pursuit as anti-tumor agents.
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents; D005419:Flavonoids / Q000494:pharmacology*; D006801:Humans; D007529:Isoflavones / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D000970:Antineoplastic Agents; D005419:Flavonoids; D007529:Isoflavones