Bacterial utilization of a hydrazine derivative as nitrogen source for growth.
The ability of microbes to metabolize the N--N bond seems rare. Pseudomonas sp. from soil can utilize 1,4,5,6-tetrahydro-6-oxo-3-pyridazinecarboxylic acid as C and N source. This appears to be the first report that a microbe can cleave a nitrogen--nitrogen bond in an organic compound and use the products for growth.
D000332:Aerobiosis; D050260:Carbohydrate Metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D006834:Hydrazines / Q000378:metabolism; D009584:Nitrogen / Q000378:metabolism*; D011549:Pseudomonas / Q000254:growth & development / Q000378:metabolism* / Q000648:ultrastructure; D011724:Pyridazines / Q000378:metabolism*; D012988:Soil Microbiology
D006834:Hydrazines; D011724:Pyridazines; D009584:Nitrogen; C020943:1,4,5,6-tetrahydro-6-oxo-3-pyridazinecarboxylic acid