title: [Malignant interstitial cell tumor of testis with a marker enzyme (author's transl)].
abstract: Metastatic interstitial cell tumor of the testis is one of the rarest human neoplasms. This is the nineteenth case to be reported. While most of these tumors are combined with hormonal dysfunction, the present tumor, apart from its uncommon hormonal profile, is remarkable because of its capacity of producing and secreting a marker enzyme, alkaline phosphatase. No response was seen after cytostatic therapy with new antineoplastic agents, such as a combination of adriamycin and cis-diamminedichloride-platinum (II), and ifosfamide. Considering the lack of radiosensitivity, surgery is the primary modality of treatment.
mesh_terms: D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood*; D006801:Humans; D007984:Leydig Cell Tumor / Q000201:enzymology* / Q000473:pathology / Q000628:therapy; D008297:Male; D009362:Neoplasm Metastasis; D013736:Testicular Neoplasms / Q000201:enzymology* / Q000473:pathology / Q000628:therapy
chemical_list: D000469:Alkaline Phosphatase
vernacular_title: Metastasierender Leydig-Zell-Tumor des Hodens mit einem Markerenzym.