Genetic associations of transitional cell carcinoma.
A series of 101 cases of transitional cell carcinoma (TCC) was contrasted with a control series for several genetic parameters. Three genetic associations were demonstrated with the TCC patients having A gene frequencies, HLA B5 and HLA CW4 genes all higher than might be expected by chance. A classification of the natural history of the disease is used to show that the HLA frequencies vary with the more or the less severe forms of the disease.
D000328:Adult; D000368:Aged; D001789:Blood Group Antigens / Q000235:genetics; D002295:Carcinoma, Transitional Cell / Q000235:genetics* / Q000473:pathology*; D003558:Cystoscopy; D005260:Female; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D014571:Urologic Neoplasms / Q000235:genetics* / Q000473:pathology
D001789:Blood Group Antigens; D006680:HLA Antigens