Kinetics of association between bisquaternary ammonium ligands and acetylcholinesterase. Evidence for two conformational states of the enzyme from stopped-flow measurements of fluorescence.
D000110:Acetylcholinesterase / Q000378:metabolism; D007700:Kinetics; D008433:Mathematics; D011485:Protein Binding; D011487:Protein Conformation; D000644:Quaternary Ammonium Compounds; D013050:Spectrometry, Fluorescence; D013329:Structure-Activity Relationship; D013997:Time Factors
D000644:Quaternary Ammonium Compounds; D000110:Acetylcholinesterase