Menorrhagia, diffuse myometrial hypertrophy and the intrauterine contraceptive device: a report of fourteen cases.
Fourteen uteri, removed for IUD-associated menorrhagia, were studied. Twelve of these IUD-bearing uteri showed pure diffuse myometrial hypertrophy; the other two uteri were enlarged as a result of multiple leiomyomas in one case and extensive deep adenomyosis in the other. The incidence of pure myometrial hypertrophy in the IUD group was far in excess of that observed in a control non-IUD-bearing menorrhagia series, where leiomyomas and/or deep adenomyosis were mostly responsible for the uterine enlargement.
D000328:Adult; D004715:Endometriosis / Q000209:etiology; D005260:Female; D006801:Humans; D006984:Hypertrophy; D007434:Intrauterine Devices / Q000009:adverse effects*; D007889:Leiomyoma / Q000209:etiology; D008595:Menorrhagia / Q000209:etiology*; D008875:Middle Aged; D009215:Myometrium / Q000473:pathology*; D009929:Organ Size; D014594:Uterine Neoplasms / Q000209:etiology; D014599:Uterus / Q000473:pathology*