[Time of doubling of the volume of malignant tumors as a criterion of the effectiveness of their treament].
The authors have studied the rate of growth and determined the time for volume doubling in 31 primary and metastatic tumors. There was found a considerable time variation for the doubling of different tumors and identical tumors in different patients. In 15 patients the period of time during which multiple pulmonary metastases doubled their volume was determined. Considerable time variations were noted in 10 of them. It is suggested to use the variations in the time of doubling as an index of the therapy efficacy. There is a statistically reliable correlation between the time of the tumor volume being doubled and patients' survival.
D000328:Adult; D004341:Drug Evaluation; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000503:physiopathology; D009362:Neoplasm Metastasis; D013997:Time Factors
Vremia udvoeniia ob"ema zlokachestvennykh opukholeĭ, kak kriteriĭ éffektivnosti ikh lecheniia.