title: Normal human endometrium in cell culture. II. A microspectrophotometric study of polyploid nuclei in short-term primary epithelial cultures.
abstract: The growth of short-term primary cultures of endometrial epithelium has been studied using Feulgen microspectrophotometry. A gradual increase in the number of polyploid nuclei up to 64C has been observed and is associated with a decline in the growth capacity of the cultures. The specific mechanism(s) of this polyploidization is not known.
mesh_terms: D002467:Cell Nucleus / Q000378:metabolism*; D046508:Culture Techniques; D004247:DNA / Q000096:biosynthesis*; D004717:Endometrium / Q000648:ultrastructure*; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008938:Mitosis; D011123:Polyploidy; D013053:Spectrophotometry
chemical_list: D004247:DNA