title: The inhibitory action of glycine on rat cortical neurons.
abstract: The action of glycine (Gly) on rat cortical neurons was studied. Gly, iontophoretically applied, hyperpolarized the membrane potential, blocked the firing rate and decreased the amplitude of EPSP-IPSP sequences. Generally the membrane resistance during the aminoacid ejection decreased. The role of Gly in the rat cortical inhibition is discussed.
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology*; D005998:Glycine / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D012964:Sodium / Q000494:pharmacology
chemical_list: D012964:Sodium; D005998:Glycine