title: Nucleotide sequence of the gene coding for the major protein of hepatitis B virus surface antigen.
abstract: DNA extracted from hepatitis B virus Dane particles has been cloned in bacteria using a plasmid vector. A full-length clone has been examined by restriction endonuclease analysis, and the nucleotide sequence of an 892-base pair fragment from cloned hepatitis B viral DNA encoding the surface antigen gene is reported. The amino acid sequence deduced from the DNA indicates that the surface antigens is a protein consisting of 226 amino acids and with a molecular weight of 25,398. The portion of the gene coding for this protein apparently contains no intervening sequences.
mesh_terms: D000954:Antigens, Surface / Q000235:genetics*; D000956:Antigens, Viral / Q000235:genetics*; D001483:Base Sequence; D004279:DNA, Viral / Q000235:genetics; D005796:Genes; D006515:Hepatitis B virus / Q000235:genetics*; D014764:Viral Proteins / Q000235:genetics
chemical_list: D000954:Antigens, Surface; D000956:Antigens, Viral; D004279:DNA, Viral; D014764:Viral Proteins