Rat growth hormone gene: intervening sequences separate the mRNA regions.
Rat genomic DNA was digested with various restriction endonucleases, separated by gel electrophoresis and hybridized to 125 I-labeled mRNA for the precursor protein to growth hormone. Restriction sites were found within the genomic DNA that were not found in the previously reported DNA sequence corresponding to the mRNA (19). It appears that the gene for growth hormone contains intervening sequences separating the DNA regions that specify mRNA sequences.
D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D004247:DNA / Q000378:metabolism; D004262:DNA Restriction Enzymes; D005796:Genes; D013006:Growth Hormone / Q000096:biosynthesis*; D008970:Molecular Weight; D009693:Nucleic Acid Hybridization; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats; D014158:Transcription, Genetic
D012333:RNA, Messenger; D013006:Growth Hormone; D004247:DNA; D004262:DNA Restriction Enzymes