Anti-HBe and subtypes of HBsAg among asymptomatic HBsAg carriers.
Finnish HBsAg positive blood donors were analyzed for the HBsAg subtype distribution and the presence of e antigen (HBeAg) and antibody to e (anti-HBe). 88% (159 of 180) of the donors had subtype and ad and 12% (21 of 180) had ay. HBeAg was found in 1% (2 of 180) and anti-HBe in 74% (133 of 180) of the donors. Anti-HBe was significantly (p less than 0.0001) more common among donors with subtype ad than with ay: 80 and 29% respectively. The mean age of donors with both subtype ad and anti-HBe was significantly (p less than 0.001) lower than that of the other donor categories.
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000914:Antibodies, Viral / Q000235:genetics*; D005260:Female; D005387:Finland; D005787:Gene Frequency; D006580:Genetic Carrier Screening; D006510:Hepatitis B Antibodies / Q000235:genetics*; D006514:Hepatitis B Surface Antigens / Q000235:genetics*; D006801:Humans; D008297:Male
D000914:Antibodies, Viral; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D000410:Alanine Transaminase