title: Quantitative comparisons of the pulmonary toxicity of tobacco and NSM smoke.
abstract: Smoking elicits a panacinar rise in pulmonary alveolar lysosomal activity that is thought to correlate with the irritancy of the smoke. Quantitative image analysis of lung sections stained histochemically for acid phosphatase indicates that tobacco smoke is significantly more irritant than NSM smoke.
mesh_terms: D000135:Acid Phosphatase; D000388:Air; D000818:Animals; D005260:Female; D007509:Irritants / Q000633:toxicity; D008168:Lung / Q000473:pathology*; D008264:Macrophages / Q000201:enzymology / Q000473:pathology; D010947:Plants, Toxic; D051381:Rats; D012906:Smoke; D014026:Nicotiana
chemical_list: D007509:Irritants; D012906:Smoke; D000135:Acid Phosphatase