Assignment of a gene for uridine diphosphate galactose-4-epimerase to human chromosome 1 by somatic cell hybridization, with evidence for a regional assignment to 1pter yields 1p21.
The presence of human uridine diphosphate galactose-4-epimerase (GALE) was found to correlate with the presence of chromosome 1 in somatic cell hybrids between man and mouse. The gene for GALE can therefore be assigned to human chromosome 1. Using a chromosome 1 rearrangement, we have been able to regionally assign GALE to the pter yields p21 region.
D000818:Animals; D002238:Carbohydrate Epimerases / Q000235:genetics*; D002874:Chromosome Mapping; D002900:Chromosomes, Human, 1-3; D006801:Humans; D006822:Hybrid Cells / Q000201:enzymology*; D051379:Mice; D014534:UDPglucose 4-Epimerase / Q000235:genetics*
D002238:Carbohydrate Epimerases; D014534:UDPglucose 4-Epimerase