title: Frequency of glutathione reductase, pyruvate kinase and glucose-6-phosphate dehydrogenase deficiency in a Spanish population.
abstract: The frequencies of deficiencies of glutathione reductase (GSSG-R), pyruvate kinase (PK) and glucose-6-phosphate dehydrogenase (G6PD) in a Spanish sample are presented. A total of 2,129 individuals was analyzed for GSSG-R, 1,636 for PK, and 1,066 (629 males and 437 females) for G6PD. Beutler's method was used. The frequencies obtained for these deficiencies were: GSSG-R, 0.09%; PK, 0.24%; and G6PD, 0.79%. The results are discussed.
mesh_terms: D005260:Female; D005787:Gene Frequency; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000453:epidemiology*; D005980:Glutathione Reductase / Q000172:deficiency*; D006801:Humans; D008297:Male; D008661:Metabolism, Inborn Errors / Q000453:epidemiology*; D011770:Pyruvate Kinase / Q000172:deficiency*; D013030:Spain
chemical_list: D005980:Glutathione Reductase; D011770:Pyruvate Kinase