[Effect of agents used in the therapy of acute ischemic heart disease on the histomorphological changes in the myocardium in acute dystrophy].
The morphological analysis of the portions of the interventricular septum and left ventricular wall in cats has revealed dystrophic and necrotic changes in the myocardium after administration of caffeine followed by adrenaline: haemorrhages, intravascular thrombogenesis, dystrophic and necrobiotic changes in myocytes. In early periods of acute ischemic heart disease morphine, fibrinolysin, heparin and Inosie F either abolished (fibrinolysin) or considerably decreased (heparin and Inosie F) a tendency toward intravascular thrombogenesis and damage to the myocardial parenchyma.
D000208:Acute Disease; D000818:Animals; D002110:Caffeine / Q000008:administration & dosage; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D002415:Cats; D003327:Coronary Disease / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology; D004353:Drug Evaluation, Preclinical; D004837:Epinephrine / Q000008:administration & dosage; D006321:Heart / Q000187:drug effects*; D009206:Myocardium / Q000473:pathology*; D013997:Time Factors
D002317:Cardiovascular Agents; D002110:Caffeine; D004837:Epinephrine
Vliianie sredstv, ispol'zuemykh v terapii ostroĭ ishemicheskoĭ bolezni serdtsa, na gistomorfologicheskie izmeneniia v miokarde pri ego ostroĭ distrofii.