Turnover of mouse photoreceptor outer segments in constant light and darkness.
Pigmented mice differ from frogs in that lighting regime has only a small effect on rod outer segment turnover. During 8 days in constant light or darkness, disc addition measured as total displacement of a radioactive band in rod outer segments of mice which has received injections of tritiated amino acids was never modified by more than 7% compared to cyclic light controls. Disc shedding continued in each lighting regime, and as judged from outer segment dimensions, disc shedding approximately balanced disc addition.
D000818:Animals; D001345:Autoradiography; D003624:Darkness; D007930:Leucine; D008027:Light; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009898:Optic Disk / Q000502:physiology; D010586:Phagocytes; D010649:Phenylalanine; D010775:Photic Stimulation; D010786:Photoreceptor Cells / Q000502:physiology*; D014316:Tritium
D014316:Tritium; D010649:Phenylalanine; D007930:Leucine