Structural alterations in normal and axotomized facial nucleus neurons after treatment with morphine.
Chronic morphine administration induced ultrastructural alterations in neurons of the facial nucleus and increased the incidence of cell death after axotomy. These findings may correlate with the significant depression of neuronal metabolism known to occur after opiate treatment.
D000818:Animals; D001369:Axons / Q000502:physiology; D005154:Facial Nerve / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D009020:Morphine / Q000494:pharmacology*; D009474:Neurons / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure*; D051381:Rats
D009020:Morphine