[Renal osteodystrophy in two children : a comparison of the effects of 1 alpha-hydroxycholecalciferol (author's transl)].
Two children suffering from renal osteodystrophy were treated by 1 alpha hydroxycholecalciferol (1 alpha OHD3) 1 microgr. each day, for 18 months. In both the level alkaline phosphatase decreased at the same time as endogenous immunoreactive CT increased, iPTH did not change steadily, whereas plasma creatinine rise. As plasma calcium concentration did not increase, it is suggested that the increase in endogenous CT concentration is a part of the favourable response to the treatment by 1 alpha OHD3.
D000469:Alkaline Phosphatase / Q000097:blood; D002116:Calcitonin / Q000097:blood; D002648:Child; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000097:blood / Q000188:drug therapy*; D003404:Creatinine / Q000097:blood; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use*; D010281:Parathyroid Hormone / Q000097:blood
D006887:Hydroxycholecalciferols; D010281:Parathyroid Hormone; D002116:Calcitonin; D003404:Creatinine; D000469:Alkaline Phosphatase
Comparaison de deux cas d'ostéodystrophie rénale sévère chez l'enfant, traités par la 1 alpha hydroxycholecalciferol (1 alpha OHD).