[Comparative clinical investigation of oral contraceptives with different doses (author's transl)].
The investigation of four oral contraceptives with different doses in adolescent girls showed that bleeding disturbances occur more frequently with low-dose preparations at the beginning of treatment. Nevertheless, these disturbances should be considered indicative of lesser central suppression. For this reason adolescent girls -- especially those with still immature cycles -- should be treated chiefly with preparations having only a low inhibitory effect on the central endocrine system in order not to disturb the maturation of the cycle.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D003276:Contraceptives, Oral / Q000008:administration & dosage*; D003278:Contraceptives, Oral, Hormonal / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004997:Ethinyl Estradiol / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008234:Lynestrenol / Q000008:administration & dosage; D008599:Menstruation Disturbances / Q000139:chemically induced
D003276:Contraceptives, Oral; D003278:Contraceptives, Oral, Hormonal; D004997:Ethinyl Estradiol; D008234:Lynestrenol
Vergleichende klinische Untersuchungen mit verschieden dosierten oralen Kontrazeptiva.