[Bioavailability of ampicillin suspensions].
The rate of ampicillin transfer into solution from suspensions of 2 types, i.e. suspensions of anhydrous ampicillin and suspensions of ampicillin trihydrate was studied. Conditions for estimation of the rate of ampicillin dissolution from the suspensions were developed. The pharmacokinetics of the pharmaceutical forms was studied on dogs. Definite advantages of the anhydrous ampicillin suspension were shown as compared to the ampicillin trihydrate suspension.
D000667:Ampicillin / Q000097:blood / Q000494:pharmacology*; D000818:Animals; D001682:Biological Availability; D004285:Dogs; D066298:In Vitro Techniques; D007700:Kinetics; D011208:Powders; D012995:Solubility; D013535:Suspensions; D013997:Time Factors
D011208:Powders; D013535:Suspensions; D000667:Ampicillin
Biodostupnost' suspenziĭ ampitsillina.