JC human papovavirus replication in human amnion cells.
JC human papovavirus was found to replicate in primary human amnion cells. The virus has undergone eight passages in amnion cells and was identified by serological methods as JC virus. By restriction endonuclease analysis of the viral DNA, the fragments observed were identical to those previously reported for the prototype strain.
D000650:Amnion; D000956:Antigens, Viral / Q000032:analysis; D046508:Culture Techniques; D003588:Cytopathogenic Effect, Viral; D004279:DNA, Viral / Q000032:analysis; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000382:microbiology; D008970:Molecular Weight; D027383:Papillomaviridae / Q000032:analysis / Q000254:growth & development* / Q000276:immunology; D027382:Polyomaviridae; D014779:Virus Replication
D000956:Antigens, Viral; D004279:DNA, Viral