Influenza hemagglutination-inhibiting antibodies in hospitalized children. Distribution of specific activity into IgM, IgG and IgA classes.
Sera from 75 children hospitalized with a clinical diagnosis of acute respiratory virus disease were tested by hemagglutination-inhibition as regards influenza A2 and B antibody shifts. In 48 patients there was an antibody shift during the clinical evolution of the disease (against influenza A2 in 34, B-- in 11, A2 and B in 3cases). A significant proportion of sera with antibody shift associated with a decrease of serum IgG levels and with an increase of serum IgM and IgA levels.
D000914:Antibodies, Viral / Q000145:classification*; D002675:Child, Preschool; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins / Q000276:immunology*; D007223:Infant; D009980:Influenza A virus / Q000276:immunology; D007251:Influenza, Human / Q000175:diagnosis / Q000276:immunology*
D000914:Antibodies, Viral; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins