Changes in hexokinase properties during transformation and subsequent proliferation of liver cells.
The activity and subcellular distribution of hexokinase in liver and several hepatomas were studied. The differences were found in the behavior of this enzyme in spontaneous, primary induced and transplantable hepatomas as compared with normal liver.
D000818:Animals; D004052:Diethylnitrosamine; D006593:Hexokinase / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced / Q000201:enzymology*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008930:Mitochondria, Liver / Q000201:enzymology; D051381:Rats; D013347:Subcellular Fractions / Q000201:enzymology
D004052:Diethylnitrosamine; D006593:Hexokinase