The Leeds results for radiotherapy in HBO for carcinoma of the head and neck.
Follow-up data at five years are reported for 24 patients with squamous cell carcinoma of the head and neck, included in a randomised prospective MRC study of radiotherapy in hyperbaric oxygen (10 fractions) or air (15 or 20 fractions). Although few, the data show a significant gain in local control (P less than 0.001) and survival (P less than 0.05) with the use of hyperbaric oxygen but no increased tissue reactions or morbidity.
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D006258:Head and Neck Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D008875:Middle Aged; D011879:Radiotherapy Dosage; D011897:Random Allocation; D013997:Time Factors