title: [Persistent chronic hepatitis. Anatomical and functional study].
abstract: A functional study was made of 40 patients with bioptically diagnosed CPH. Fractional BSF clearance was the most frequently altered test and its correlation with the anatomical damage was significant. In particular, the fractional uptake clearance (K1) gave a pointer to both the presence of liver damage and its type. Elimination clearance (K2) may also be useful, especially in the differentiation of histological pictures on the borderline between CAH and CPH. In the evaluation of CPH, therefore, BSF clearance is of marked assistance both in rounding out the histological diagnosis, and in cutting down the need for control biopsies.
mesh_terms: D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood; D001663:Bilirubin / Q000097:blood; D002908:Chronic Disease; D005260:Female; D006505:Hepatitis / Q000097:blood* / Q000201:enzymology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008875:Middle Aged; D013448:Sulfobromophthalein; D000637:Transaminases / Q000097:blood
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D013448:Sulfobromophthalein; D000637:Transaminases; D000469:Alkaline Phosphatase; D001663:Bilirubin
vernacular_title: L'epatite cronica persistente. Studio anatomo-funzionale.