Catalase and dehydroascorbate reductase in human polymorphonuclear leukocytes (PMN): possible functional relationship.
In leukocytes (PMN) of individuals with Swiss type acatalasemia, the rate of dehydroascorbate reduction is 4 times normal. This observation suggests that the protective function served by catalase in human PMN is supported by dehydroascorbate reductase.
D020642:Acatalasia; D002374:Catalase / Q000097:blood*; D003683:Dehydroascorbic Acid; D005979:Glutathione Peroxidase / Q000097:blood; D005980:Glutathione Reductase / Q000097:blood; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D009247:NADH, NADPH Oxidoreductases / Q000097:blood*; D009504:Neutrophils / Q000201:enzymology*; D010587:Phagocytosis; D013482:Superoxide Dismutase / Q000097:blood
D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D009247:NADH, NADPH Oxidoreductases; D005980:Glutathione Reductase; D003683:Dehydroascorbic Acid