title: The cryosurgical treatment of intraepithelial neoplasia.
abstract: At the Finseninstituttet and the Radium Centre in Copenhagen, from 1971-1975 inclusive, cryosurgery was carried out altogether 59 times on 57 patients. Only 8 patients showed histopathological changes in the biopsies sufficient to indicate conization. Hysterectomy was carried out on 8 patients. In 7 of these the removed uteri showed either no malignant changes or changpy. Invasive growth was discovered only in 1 patient, who later underwent a total hysterectomy by the Wertheim method. A biopsy on 1 patient with carcinoma in situ, suspected invasive growth, was treated with radium.
mesh_terms: D000328:Adult; D002278:Carcinoma in Situ / Q000473:pathology / Q000601:surgery*; D002584:Cervix Uteri / Q000473:pathology; D003452:Cryosurgery / Q000379:methods*; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007044:Hysterectomy; D008875:Middle Aged; D011247:Pregnancy; D002578:Uterine Cervical Dysplasia / Q000473:pathology / Q000601:surgery*; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*