title: An association between primary biliary cirrhosis and jejunal villous atrophy resembling celiac disease.
abstract: A 76-year-old female presented with malabsorption and was subsequently shown to have jejunal villous atrophy. There was only partial clinical and histologic recovery with gluten withdrawal, but this was thought to be due to poor adherence to the diet. The findings were considered to be consistent with adult celiac disease. During the course of investigations, she was also found to have primary biliary cirrhosis. This is the fifth recorded instance of this association and the first from North America. Because these are uncommon conditions, it is postulated that this is unlikely to be a chance association. The recognition of this coexistence is of practical importance in the investigation and treatment of patients with primary biliary cirrhosis and celiac disease.
mesh_terms: D000368:Aged; D001284:Atrophy; D002446:Celiac Disease / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007583:Jejunum / Q000473:pathology; D008099:Liver / Q000473:pathology; D008105:Liver Cirrhosis, Biliary / Q000150:complications* / Q000473:pathology; D008871:Microvilli / Q000473:pathology