title: Some particular aspects of the microarchitecture of human coronary arteries.
abstract: The following light-microscopic features characterize the microarchitecture of human coronary arteries compared with other organ arteries of muscular type and similar size: (a) the rapid development of a diffuse thickened intima which in adolescents becomes the main layer of the coronary artery wall; (b) the slow post-natal increase in the number of circularly oriented rows of smooth muscle cells of the media; (c) the occurrence of numerous longitudinal muscle columns, particularly in arterial segments and branches which run from the base to the apex of the heart; (d) the complex organization of branching points, including the presence of large pads or cushions, a very thick intima and many longitudinal muscle columns, some of which exhibit a spiral course at the level of the branch mouths with the formation of muscle rings round the entrance orifices.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D003331:Coronary Vessels / Q000033:anatomy & histology* / Q000196:embryology / Q000254:growth & development; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009130:Muscle, Smooth / Q000033:anatomy & histology / Q000196:embryology