[Cardiotropic effect of anti-arrhythmia agents].
In experiments on contractile proteins isolated from the myocardium rather than from the musculus gastrocnemius it was shown that in contradistinction to lidocain the drugs quinine, quinidine, novocainamide, papaverin, obsidan and isoptin at a concentration of 3 . 10(-4) M inhibit contraction of actomyosin threads and superprecipitation reaction of actomyosin suspension that occurs under the influence of adenosine triphosphoric acid.
D000205:Actomyosin / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D004347:Drug Interactions; D006321:Heart / Q000187:drug effects*; D066298:In Vitro Techniques; D009200:Myocardial Contraction / Q000187:drug effects; D011817:Rabbits
D000889:Anti-Arrhythmia Agents; D000255:Adenosine Triphosphate; D000205:Actomyosin
O kardiotropnom éffekte protivoaritmicheskikh sredstv.