title: Bone scanning in otolaryngology.
abstract: Modern radionuclide bone scanning has introduced a new concept in physiologic and anatomic diagnostic imaging to general medicine. As otolaryngologists must diagnose and treat disease in relation to the bony and/or cartilaginous supporting structures of the neurocranium and upper airway, this modality should be included in the otolaryngologist's diagnostic armamentarium. It is the purpose of this manuscript to study the specific applications of bone scanning to our specialty at this time, based on clinical experience over the past three years. This thesis describes the development of bone scanning in general (history of nuclear medicine and nuclear physics; history of bone scanning in particular). General concepts in nuclear medicine are then presented; these include a discussion of nuclear semantics, principles of radioactive emmissions, the properties 99mTc as a radionuclide, and the tracer principle. On the basis of these general concepts, specific concepts in bone scanning are then brought forth. The physiology of bone and the action of the bone scan agents is presented. Further discussion considers the availability and production of the bone scan agent, patient factors, the gamma camera, the triphasic bone scan and the ultimate diagnostic principle of the bone scan. Clinical applications of bone scanning in otolaryngology are then presented in three sections. Proven areas of application include the evaluation of malignant tumors of the head and neck, the diagnosis of temporomandibular joint disorders, the diagnosis of facial fractures, the evaluation of osteomyelitis, nuclear medicine imaging of the larynx, and the assessment of systemic disease. Areas of adjunctive or supplementary value are also noted, such as diagnostic imaging of meningioma. Finally, areas of marginal value in the application of bone scanning are described.
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005147:Facial Bones / Q000293:injuries; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging; D006801:Humans; D007818:Laryngeal Diseases / Q000000981:diagnostic imaging; D008722:Methods; D010019:Osteomyelitis / Q000000981:diagnostic imaging; D010038:Otorhinolaryngologic Diseases / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D012887:Skull Fractures / Q000000981:diagnostic imaging; D013667:Technetium; D013706:Temporomandibular Joint Dysfunction Syndrome / Q000000981:diagnostic imaging; D009626:Terminology as Topic
chemical_list: D013667:Technetium