Further observations on infections of guinea pigs with Venezuelan encephalitis virus strains.
Guinea pigs from a Guatemalan colony died after subcutaneous inoculating of moderately small doses of equine-benign strains of Venezuelan encephalitis (VE) virus of hemagglutination-inhibition subtype I-E from enzootic habitats in Mexico and Guatemala. Thus these guinea pigs were unlike English short hair and inbred 13 guinea pigs, which usually survive infections with equine-benign VE strains of subtype I-E. We therefore caution others that not all strains of guinea pigs can be used to evaluate the potential equine virulence of VE viruses.
D000818:Animals; D004666:Encephalitis Virus, Venezuelan Equine / Q000472:pathogenicity*; D004683:Encephalomyelitis, Equine / Q000662:veterinary*; D004685:Encephalomyelitis, Venezuelan Equine / Q000382:microbiology / Q000662:veterinary*; D005260:Female; D006166:Guatemala; D006168:Guinea Pigs / Q000382:microbiology; D008297:Male; D013045:Species Specificity