Actinic reticuloid. A clinical, pathologic, and action spectrum study.
A 54-year-old man suffered from a chronic dermatitis that was more severe on light-exposed areas. Skin biopsy specimens revealed histopathologic findings consistent with those seen in mycosis fungoides. Ultrastructural studies demonstrated the existence of lymphoid cells with hyperconvoluted nuclei, typical of the mycosis fungoides cell or Sézary cell, within the epidermis, dermis, and peripheral blood. Light testing with a monochromator showed abnormal photosensitivity to both short- and long-wave ultraviolet light as well as to the violet, blue, and green wavelengths of visible light. The features of this patient's disease indicate actinic reticuloid.
D001706:Biopsy; D002467:Cell Nucleus / Q000648:ultrastructure; D002908:Chronic Disease; D003872:Dermatitis / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000175:diagnosis; D010787:Photosensitivity Disorders / Q000175:diagnosis* / Q000473:pathology; D012867:Skin / Q000473:pathology*