Mechanism of cataract production by 3-beta(2-diethylaminoethoxy) androst-5-en-17-one hydrochloride, U18666A: an inhibitor of cholesterol biosynthesis.
D000375:Aging; D000736:Androstenes / Q000633:toxicity*; D000818:Animals; D000924:Anticholesteremic Agents / Q000633:toxicity*; D002386:Cataract / Q000139:chemically induced* / Q000378:metabolism; D002784:Cholesterol / Q000096:biosynthesis; D003459:Crystallins / Q000096:biosynthesis; D003897:Desmosterol / Q000378:metabolism; D004195:Disease Models, Animal; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D007908:Lens, Crystalline / Q000378:metabolism; D008297:Male; D011188:Potassium / Q000378:metabolism; D051381:Rats; D012964:Sodium / Q000378:metabolism
D000736:Androstenes; D000924:Anticholesteremic Agents; D003459:Crystallins; D003897:Desmosterol; D002784:Cholesterol; D012964:Sodium; D011188:Potassium