Hypertension among Aleuts.
Surveys of Aleuts on St. Paul Island, Alaska, in 1966 and 1976 found a prevalence of hypertension as high as any reported in the United States. The rate remained high over the 10-year period. Preliminary data from other Aleut villages on the Aleutian Chain indicate that a high prevalence of hypertension may be widespread in this region. Etiologically genetic factors, obesity, and a high salt intake are all present. In addition, an exceedingly high level of cadmium content was found in seal livers, a dietary staple. Isolated locations such as St. Paul provide natural laboratories for possibly elucidating the complex etiology of this disease.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000413:Alaska; D000818:Animals; D002104:Cadmium / Q000009:adverse effects / Q000032:analysis; D004032:Diet / Q000009:adverse effects; D005260:Female; D006801:Humans; D006973:Hypertension / Q000139:chemically induced / Q000453:epidemiology* / Q000209:etiology; D004930:Inuit; D008297:Male; D008460:Meat / Q000032:analysis; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D046048:Seals, Earless
D002104:Cadmium