[Immune and autoimmune reactions in the mechanism of action of drug substances, their detoxication and the development of habituation to them].
It has been shown that rausedyl administration is followed by enhanced synthesis of autoantibodies to serotonine and adrenaline. Meanwhile bucarban enhances the synthesis of autoantibodies to endogenous insulin and ACTH to hydrocortisone and testosterone. Activation of the autoimmune system of regulating the balance of endogenous compounds was shown by an increased number of specific antibody-producing cells in the organs and tissues and by the growth of the titer of circulating antibodies in the blood.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D000918:Antibody Specificity / Q000187:drug effects; D000937:Antigen-Antibody Reactions / Q000187:drug effects*; D001323:Autoantibodies / Q000032:analysis / Q000096:biosynthesis / Q000276:immunology*; D002478:Cells, Cultured; D004361:Drug Tolerance; D004364:Pharmaceutical Preparations / Q000276:immunology*; D011234:Precipitins / Q000032:analysis; D051381:Rats; D012397:Rosette Formation; D013997:Time Factors
D000906:Antibodies; D001323:Autoantibodies; D004364:Pharmaceutical Preparations; D011234:Precipitins
Immunnye i autoimmunnye reaktsii v mekhanizme deĭstviia lekarstvennykh veshchestv, ikh detoksikatsii i razvitiia pyrivykaniia k nim.