title: Staphylococcal septic arthritis in three horses.
abstract: Three horses were diagnosed as having monarticular septic arthritis due to Staphylococcus aureus on the basis of culture of articular cartilage, synovial membrane and/or synovial fluid. The organisms were all well recognised human phage types and in two cases demonstrated beta-lactamase (penicillinase) activity. Details of case histories are presented and the bacteriological techniques and antibiotic management with cloxacillin, methicillin and penicillin discussed. Following treatment, sterile cultures of synovial fluid were achieved in all cases, but in two horses the infections resulted in degenerative articular changes. This necessitated arthrodesis of the fetlock joint in one case.
mesh_terms: D000818:Animals; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D002358:Cartilage, Articular / Q000382:microbiology; D003023:Cloxacillin / Q000627:therapeutic use; D005260:Female; D005552:Forelimb; D006614:Hindlimb; D006734:Horse Diseases / Q000188:drug therapy; D006736:Horses; D008297:Male; D008712:Methicillin / Q000627:therapeutic use; D011183:Postoperative Complications / Q000188:drug therapy / Q000662:veterinary; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D013211:Staphylococcus aureus / Q000302:isolation & purification; D013582:Synovial Fluid / Q000382:microbiology
chemical_list: D003023:Cloxacillin; D008712:Methicillin