title: [Pathohistologic and biochemical changes in the brain in atherosclerotic dementia].
abstract: The data obtained from studies of 48 postmortem cases of atherosclerotic dementia with the use of histological and biochemical methods demonstrated a prevalence of ischemic changes in the nervous cells, cells-shadows, demyelinization, fragmentation of nervous filaments, hyperplasia, hypertrophy of astrocytes, a swelling of oligodendroglia compared to other changes. A drop in the amount of lecithin in the brain is the highest, while that in kefaline fractions is the lowest. A drop in the amount of sphyngomyelin occupies a middle place.
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology*; D001923:Brain Chemistry; D002540:Cerebral Cortex / Q000473:pathology; D002784:Cholesterol / Q000032:analysis; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D008578:Meninges / Q000473:pathology; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D010743:Phospholipids / Q000032:analysis
chemical_list: D010743:Phospholipids; D002784:Cholesterol
vernacular_title: Patogistologicheskie i biokhimicheskie izmeneniia golovnogo mozga pri ateroskleroticheskom slaboumii.