Intravenous zinc sulfate therapy in zinc-depleted patients.
Zinc sulfate was administered intravenously in 3 patients with severe conditional zinc deficiency. The dosage ranged from 10 to 20 mg ionic zinc daily, and the duration of the treatment did not exceed 2 weeks. The rise in serum zinc and urinary zinc per 24 h, as well as in serum alkaline phosphatase, occurred at a faster rate than observed in a patient who was given 135 mg zinc daily by mouth. No subjective or biochemical side effects of the intravenous zinc therapy was observed.
D000469:Alkaline Phosphatase / Q000097:blood; D006801:Humans; D007275:Injections, Intravenous; D015032:Zinc / Q000008:administration & dosage / Q000172:deficiency* / Q000378:metabolism / Q000627:therapeutic use*
D000469:Alkaline Phosphatase; D015032:Zinc