[Medical support in surgery for pheochromocytoma].
The occurrence of hypertensive crises, arrhythmias and hypotensive crises during surgery for pheochromocytoma can be prevented both preoperatively and intraoperatively by adequate alpha-adrenergic blockade and volume replacement. Only in a few cases is additional beta-adrenergic blockade necessary. Preoperatively the author uses phenoxybenzamine (Dibenicyline) as alpha-blockade in a dose of 20-30 mg daily, and propanolol (Inderal) as beta-blockade in a dose of 4 X 20 mg daily, both given orally. Intraoperatively he gives preference to alpha-adrenergic receptor blockers with a short halflife, i.e. phentolamine (Regitin) and lidocaine or pranolol as the beta-adrenergic blocker.
D000310:Adrenal Gland Neoplasms / Q000601:surgery*; D001145:Arrhythmias, Cardiac / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000517:prevention & control*; D007022:Hypotension / Q000209:etiology / Q000517:prevention & control*; D007431:Intraoperative Complications / Q000517:prevention & control; D008012:Lidocaine / Q000627:therapeutic use*; D010643:Phenoxybenzamine / Q000627:therapeutic use*; D010646:Phentolamine / Q000627:therapeutic use*; D010673:Pheochromocytoma / Q000601:surgery*; D011292:Premedication; D011433:Propranolol / Q000627:therapeutic use*
D010643:Phenoxybenzamine; D008012:Lidocaine; D011433:Propranolol; D010646:Phentolamine
Die medikamentöse Unterstützung bei Phäochromozytomoperationen.