Enhancement of the antitumor effect of illudin S by including it into liposomes.
Entrapping illudin S in liposome markedly enhanced life prolonging effect in ddN mice bearing Ehrlich ascites tumors, presumably by decreasing the side effects.
D000818:Animals; D000903:Antibiotics, Antineoplastic; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D008081:Liposomes; D051379:Mice; D012717:Sesquiterpenes / Q000627:therapeutic use*; D013141:Spiro Compounds / Q000627:therapeutic use
D000903:Antibiotics, Antineoplastic; D008081:Liposomes; D012717:Sesquiterpenes; D013141:Spiro Compounds