[Effect of cyclophosphane on the function and structure of the kidneys].
In experiments on dogs and rats it has been shown that single administration of cyclophosphane in low doses produces no changes in the renal function or in water-electrolyte metabolism. Material changes in the canalicular apparatus of the kidneys, water-salt equilibrium and organ ultrastructure have been recorded in prolonged administration of the drug.
D000818:Animals; D003520:Cyclophosphamide / Q000494:pharmacology*; D004231:Diuresis / Q000187:drug effects; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D007668:Kidney / Q000187:drug effects* / Q000648:ultrastructure; D007677:Kidney Function Tests; D051381:Rats; D013997:Time Factors; D014882:Water-Electrolyte Balance / Q000187:drug effects
D003520:Cyclophosphamide
Vliianie tsiklofosfana na funktsiiu i strukturu pochek.