title: Changes in total body calcium on prolonged maintenance hemodialysis with high and low dialysate calcium.
abstract: In vivo neutron activation analysis was used to measure sequential changes in total body calcium in 25 unselected patients with end-stage renal disease on dialysis for a period as long as 5 years. In 7 unselected patients (group 1), dialysis with a calcium solution of 5.0 mg/100 ml resulted in significant calculated daily loss of calcium (-321 +/- SEM 76 mg/day) while dialysis with 6.5 mg/100 ml resulted in a significant calculated calcium gain (182 +/- SEM 103 mg/day; p less than 0.0025). The remaining 18 patients (group 2) were dialyzed with a dialysate calcium of 6.5 mg/100 ml and sequential total body calcium measurements showed no significant calcium losses (-12 +/- SEM 68 mg/day) for a period as long as 2 years.
mesh_terms: D002118:Calcium / Q000008:administration & dosage / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D009501:Neutron Activation Analysis; D006435:Renal Dialysis; D012996:Solutions
chemical_list: D012996:Solutions; D002118:Calcium