Temporary culture in isoleucine-free medium enhances transformation of 10T1/2 cells by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D004247:DNA / Q000378:metabolism; D007532:Isoleucine / Q000378:metabolism; D007700:Kinetics; D008769:Methylnitronitrosoguanidine / Q000494:pharmacology*; D051379:Mice
D007532:Isoleucine; D008769:Methylnitronitrosoguanidine; D004247:DNA