Adipose cell size in spontaneously hypertensive rats (SHR).
The size of adipose cells in spontaneously hypertensive rats (SHR) and normotensive controls has been evaluated at 4, 8 and 26 weeks of age. Age-matched groups showed significant differences only in 8-week-old rats, but this can be explained by the lower body weight of SHR. In both groups of animals fat cell size varies with body weight (r = 0.965 in SHR and r = 0.863 in normotensive rats) independent of the stage of hypertension. The regression lines are not significantly different. Thus, no evidence of enlarged adipocytes in SHR has been obtained.
D000273:Adipose Tissue / Q000473:pathology*; D000367:Age Factors; D000818:Animals; D001835:Body Weight; D006973:Hypertension / Q000473:pathology*; D008297:Male; D051381:Rats