[Change in the dependence of lymphocyte reactivity to phytomitogens on endogenous hormonal factors in experimental bacterial lesion of the prostate].
The relationship between the blast lymphocyte transformation response (BLTR) to PHA P, Con A, PWM and 11-hydroxycorticosteroids (I) and the testosterone (II) levels in the blood plasma and the excretion of 17-ketosteroids with the urine were studied in 11 dogs with experimental urogenous prostatitis, provoked by Staphylococcus aureus, isolated from a patient with chronic prostatitis. Multiple correlation between the BLTR and hormonal factors was noted before the experiment. It was disturbed in a month and restored 2 months after the beginning of the experiment. Before the studies the relationships were mainly realized by direct correlation with 1 and 2 months after the experiment--due to the negative correlation with II. A homeostatic nature of the hormone lymphoid relationship with respect to 11-hydroxy-corticosteroids is suggested.
D000728:Androgens / Q000502:physiology*; D000818:Animals; D004285:Dogs; D004306:Dose-Response Relationship, Immunologic; D037102:Lectins / Q000494:pharmacology*; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects*; D008297:Male; D011472:Prostatitis / Q000276:immunology*; D013203:Staphylococcal Infections / Q000276:immunology*; D013997:Time Factors
D000728:Androgens; D037102:Lectins
Izmenenie zavisimosti reaktivnosti limfotsitov na fitomitogeny ot éndogennykh gormonal'nykh faktorov pri éksperimental'nom bakterial'nom porazhenii predstatel'noĭ zhelezy.