A high molecular weight inhibitor of Ca2+ -dependent neutral protease in rat brain.
An endogenous, heat-stable inhibitor of high mol. wt (approximately 3x10(5)) was found to be present in rat brain, which inhibited Ca2+-dependent neutral protease specifically but not due to its binding of Ca2+ in the medium .
D000818:Animals; D001921:Brain / Q000201:enzymology*; D001923:Brain Chemistry; D002118:Calcium / Q000494:pharmacology*; D007700:Kinetics; D010447:Peptide Hydrolases / Q000378:metabolism*; D011480:Protease Inhibitors / Q000302:isolation & purification*; D051381:Rats
D011480:Protease Inhibitors; D010447:Peptide Hydrolases; D002118:Calcium