Vaginal epithelialization with human amnion.
Human amnion is a readily available and inexpensive allograft with low antigenicity, high antimicrobial potential, and the ability to foster epithelialization. It has been used to reconstruct the vagina in 2 patients following vaginectomy for diffuse carcinoma in situ (CIS) and in 1 patient following severe, corrosive, vulvovaginal burns. It was also used to construct the vagina in 1 patient with müllerian agenesis. In all 4 cases, epithelialization was complete within 8 weeks.
D000293:Adolescent; D000328:Adult; D000650:Amnion / Q000637:transplantation*; D002057:Burns, Chemical / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D014184:Transplantation, Homologous; D014621:Vagina / Q000002:abnormalities / Q000293:injuries / Q000601:surgery*; D014625:Vaginal Neoplasms / Q000601:surgery