title: The calculation of annual limits of intake for plutonium-239 in man using a bone model which allows for plutonium burial and recycling.
abstract: Values of the annual limit of intake (ALI) for plutonium-239 in man have been calculated using committed dose equivalent limits as recommended by ICRP in Publication 26. The calculations were made using a multicompartment bone model which allows for plutonium burial and recycling in the skeleton. In one skeletal compartment, the growing surfaces of cortical bone, it is assumed that plutonium deposits are retained and are not subject to resorption or recycling. In the trabecular bone compartment plutonium is taken to be resorbed with either subsequent redeposition onto bone surfaces or retention in the bone marrow. ALIs for plutonium-239 have been calculated assuming a range of rates of bone accretion (0-32 micron yr-1), different amounts of plutonium retained in the marrow (0-60%) and a 20%, 45% or 70% deposition of plutonium in the skeleton from the blood. The calculations made using this bone model suggest that 750 Bq (20 nCi) is an appropriate ALI for the inhalation of class W and class Y plutonium compounds and that 830 kBq and 5 MBq (23 muCi and 136 muCi) are the appropriate ALIs for the ingestion of soluble and insoluble forms of plutonium respectively.
mesh_terms: D000284:Administration, Oral; D000336:Aerosols; D001853:Bone Marrow / Q000528:radiation effects*; D001842:Bone and Bones / Q000528:radiation effects*; D006801:Humans; D008452:Maximum Allowable Concentration; D008954:Models, Biological; D011005:Plutonium / Q000008:administration & dosage; D011829:Radiation Dosage; D013269:Stochastic Processes
chemical_list: D000336:Aerosols; D011005:Plutonium