title: Mortality from chronic interstitial nephritis and phenacetin consumption in Denmark.
abstract: After 1950, a pronounced increase in the mortality from chronic interstitial nephritis among women was registered in Denmark. This was suspected to be caused by a contemporary increase in the consumption of drugs containing phenacetin. Restrictions were therefore imposed on the sale of such drugs in 1961 and consumption decreased sharply. This report, based upon death certificates from 1941--76, shows that the mortality rate from chronic interstitial nephritis has decreased gradually among women in Denmark since 1960, and has now reached the same level in younger women as in the 1940's.
mesh_terms: D002908:Chronic Disease; D003718:Denmark; D004363:Drug Utilization; D005260:Female; D006801:Humans; D009395:Nephritis, Interstitial / Q000139:chemically induced / Q000401:mortality*; D010615:Phenacetin / Q000009:adverse effects*
chemical_list: D010615:Phenacetin