Lymphoreticular neoplasia in a dog resembling malignant histiocytosis (histiocytic medullary reticulosis) in man.
Malignant histiocytosis was diagnosed in a 4-year-old-dog. Major clinicopathologic findings included multiple cutaneous tumors, peripheral lymphadenopathy, hepatomegaly, lytic bone lesions, anemia, thrombocytopenia, and monoclonal IgA gammopathy. Pathologic findings included multi-systemic infiltration of erythrophagocytic malignant histiocytes. Chemotherapy was unsuccessful.
D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D004283:Dog Diseases / Q000097:blood / Q000473:pathology; D004285:Dogs; D005260:Female; D008099:Liver / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000097:blood / Q000473:pathology / Q000662:veterinary*; D012867:Skin / Q000473:pathology