Computer-aided analysis of chromosomal aberrations occurring in an abnormal human karyotype.
A semi-automatic method for recognition of chromosomal changes is presented: from a coded description of an abnormal chromosome (formulated with the aid of an R-banding technique), a computer program makes simulations to reconstitute this chromosomal image from a group of normal chromosomes. Nine types of aberrations (see text) can thus be recognized and the aggregate structure of a group of abnormal chromosomes occurring in a human karyotype can also be rediscovered.
D002869:Chromosome Aberrations; D002871:Chromosome Banding; D003201:Computers; D006801:Humans; D007621:Karyotyping / Q000379:methods