Disseminated granuloma annulare treated with low-dose chlorambucil.
Disseminated granuloma annulare (DGA) is a frequently severe chronic and disfiguring disease that is resistant to conventional methods of therapy. In a patient with DGA, low-dose chlorambucil therapy (2 mg three times daily, orally administered) resulted in dramatic and rapid clearing of all lesions in a short period of time. To my knowledge, this is the fourth case reported in which this therapeutic modality was used.
D002699:Chlorambucil / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006099:Granuloma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D012871:Skin Diseases / Q000188:drug therapy* / Q000473:pathology
D002699:Chlorambucil