title: Choriocarcinoma and invasive mole. A review of 10 years' experience.
abstract: Experience gained in the management of 24 patients with choriocarcinoma and invasive mole admitted to Groote Schuur Hospital, Cape Town, during the past 10 years is analysed. Three high-risk patients died and 21 patients recovered without any known recurrence, giving a 'cure' rate of 87%. The modes of presentation, methods of diagnosis, and treatment, including cytotoxic therapy and the place of hysterectomy, are discussed. Patients with choriocarcinoma require special facilities, including beta-subunit human chorionic gonadotrophin assay, ultrasonography and arteriography, together with skilled treatment, and a plea is made for the referral of all patients to special treatment centres.
mesh_terms: D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000556:secondary; D002822:Choriocarcinoma / Q000175:diagnosis / Q000453:epidemiology / Q000556:secondary / Q000628:therapy*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008875:Middle Aged; D011247:Pregnancy; D011248:Pregnancy Complications; D013019:South Africa; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*