title: [Treatment of alopecia areata with D.N.C.B. (author's transl)].
abstract: The results of treatment of 16 cases of alopecia areata with dinitrochlorobenzene (D.N.C.B.) are reported. The chemical is applied to the scalp once a week, beginning three weeks after sensitivation (patch-test 1/50). We have available to us a battery of D.N.C.B. solutions of various concentrations (11 solutions ranging from 1/20,000 to 1/25). The concentration used varies at each application with the desired result being a contact dermatitis. In the 16 cases studied, 4 were classified as good results, 8 as poor and 4 as failures. Hairgrowth begins with three weeks following the first D.N.C.B. application to the scalp. Good prognostic signs include the facility in sensitizing the patient as well as the intensity of this reaction. The reasons for this treatment's efficacy being as yet unknown, the standardization, as well as the actual technique are, at the present time difficult and hazardous.
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000506:Alopecia Areata / Q000188:drug therapy*; D002648:Child; D003877:Dermatitis, Contact; D004137:Dinitrochlorobenzene / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009578:Nitrobenzenes / Q000627:therapeutic use*
chemical_list: D004137:Dinitrochlorobenzene; D009578:Nitrobenzenes
vernacular_title: Traitement de la prelade par applications locales de D.N.C.B.