title: Serum concentrations of oestradiol and progesterone during the normal oestrous cycle and early pregnancy in the lion (Panthera leo).
abstract: During a 6-month study period weekly serum samples demonstrated 9 oestradiol surges above 14 pg/ml (range 19-108 pg/ml) among 3 lionesses isolated from male lions. Intervals between peaks ranged from 3 to 8 weeks. Progesterone surges of more than 17 ng/ml (range 17-282 ng/ml) and lasting for 2-6 weeks were recorded after 7 of the oestradiol peaks. Sexual behaviour correlated well with the oestradiol peaks. Except for cornification following oestradiol peaks, there was no obvious vaginal cytology pattern at other times of the cycle. Pregnancy occurred after a 12-h contact with a male during behavioural oestrus. During gestation (108 days) oestradiol values remained low, while progesterone was elevated to 49 ng/ml within 12 h after mating, reaching a peak of 143 ng/ml at the 4th week, and remaining elevated during the next 2 months.
mesh_terms: D000818:Animals; D002335:Carnivora / Q000097:blood*; D004958:Estradiol / Q000097:blood*; D004971:Estrus; D005260:Female; D008045:Lions / Q000097:blood* / Q000502:physiology; D011247:Pregnancy; D011270:Pregnancy, Animal; D011374:Progesterone / Q000097:blood*; D012726:Sexual Behavior, Animal / Q000502:physiology; D014621:Vagina / Q000166:cytology
chemical_list: D011374:Progesterone; D004958:Estradiol