title: [Effect of the endolymphatic administration of chemical preparations on the leukocyte motor activity in stomach cancer].
abstract: The results are reported on the effect of endolymphatic administration of large doses of 5-fluorouracil and methotrexate on the rate of motion and the coefficient of the motion activity of leucocytes in peripheral blood in 20 gastric cancer patients. The functional changes were found to precede quantitative shifts in leucocytes. Two weeks after termination of the chemotherapy the rate of leucocytes motion and CMA restored to the initial values.
mesh_terms: D000328:Adult; D000368:Aged; D002465:Cell Movement / Q000187:drug effects; D004359:Drug Therapy, Combination; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage*; D005528:Foot; D006801:Humans; D007272:Injections, Intralymphatic; D007962:Leukocytes / Q000187:drug effects*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage*; D008875:Middle Aged; D011184:Postoperative Period; D011300:Preoperative Care; D013274:Stomach Neoplasms / Q000188:drug therapy*; D013997:Time Factors
chemical_list: D005472:Fluorouracil; D008727:Methotrexate
vernacular_title: Vliianie éndolimfaticheskogo vvedeniia khimiopreparatov na dvigatel'nuiu aktivnost' leĭkotsitov u bol'nykh rakom zheludka.