Endocarditis associated with porcine valve xenografts.
Review of porcine valve xenografts in 68 patients over a 32-month period disclosed seven episodes of endocarditis in six patients, an attack rate of 10%. Four patients died as a result of the infections. The presence of Staphylococcus epidermidis in every case was most striking as was the preponderance of methicillin sodium resistance. The clustering of cases within a restricted time period, and the absence of subsequent cases, suggests the strong possibility of a nosocomial occurrence.
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001021:Aortic Valve / Q000601:surgery; D001705:Bioprosthesis; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology*; D013203:Staphylococcal Infections / Q000209:etiology*; D014183:Transplantation, Heterologous
D000900:Anti-Bacterial Agents