Two survivors of severe paraquat intoxication by "continuous hemoperfusion".
"Continuous hemoperfusion" (8 h/day for 2--3 weeks) was performed in two patients suffering from severe paraquat intoxication. On account of paraquat plasma concentrations a fatal outcome due to pulmonary fibrosis would have been expected in both cases. However, both patients survived following "continuous hemoperfusion" therapy. Coated activated charcoal seems to have a higher affinity for paraquat than lung tissue.
D000208:Acute Disease; D000293:Adolescent; D002606:Charcoal / Q000627:therapeutic use; D005260:Female; D005751:Gastric Lavage; D006464:Hemoperfusion; D006801:Humans; D008297:Male; D010269:Paraquat / Q000032:analysis / Q000506:poisoning*; D013406:Suicide, Attempted; D013997:Time Factors
D002606:Charcoal; D010269:Paraquat