title: Fucose incorporation into rat hippocampus structures after acquisition of a brightness discrimination. A histoautoradiographic analysis.
abstract: Using a brigthness discrimination model in rats, the labeling of discrete hippocampus formation structures was studied after intraventricular application of [3H]-fucose. This substance was injected 5 min before training as well as 5 min, 3, 7 and 23 h after training, the pulse period lasting 120 min in all cases. A significantly training-related enhanced labeling of CA1, CA3 and CA4 cell bodies and fibres revealed that a biphasic time course occurring when radioactive fucose was applied 5 min before training and 7 h after training, whereas the increased labeling of area dentata structures was evidenced only after application of radioactive fucose 5 min before and after training. In all structures under investigation the training-related increase in labeling was more pronounced in the fibre layers than in the pyramidal and granular cell bodies.
mesh_terms: D000818:Animals; D001345:Autoradiography; D001362:Avoidance Learning; D005643:Fucose / Q000378:metabolism*; D006624:Hippocampus / Q000378:metabolism*; D008027:Light; D008297:Male; D011287:Prejudice; D051381:Rats; D014018:Tissue Distribution; D014316:Tritium; D014796:Visual Perception
chemical_list: D014316:Tritium; D005643:Fucose