50ppm MnBK subclinical neuropathy in rats.
40 rats were subjected daily for 6 months to an atmosphere containing 50ppm MnBK. 32 of the rats presented with demyelination of the sciatic nerve and 2 of these with axonal hypertrophy.
D000818:Animals; D001369:Axons / Q000187:drug effects / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D006984:Hypertrophy; D007659:Ketones / Q000494:pharmacology*; D008742:Methyl n-Butyl Ketone / Q000494:pharmacology*; D008832:Microchemistry; D009186:Myelin Sheath / Q000187:drug effects / Q000502:physiology; D051381:Rats; D012584:Sciatic Nerve / Q000187:drug effects / Q000473:pathology*
D007659:Ketones; D008742:Methyl n-Butyl Ketone