title: Achalasia and diffuse oesophageal spasm in siblings.
abstract: We report the occurrence of achalasia and diffuse oesophageal spasm in brother and sister. The familial occurrence of these unusual disorders is consistent with the possibility that they share a common aetiology and indicates the potential importance of genetic predisposition.
mesh_terms: D000328:Adult; D004931:Esophageal Achalasia / Q000000981:diagnostic imaging / Q000235:genetics* / Q000503:physiopathology; D004935:Esophageal Diseases / Q000000981:diagnostic imaging / Q000235:genetics* / Q000503:physiopathology; D004947:Esophagus / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011312:Pressure; D011859:Radiography; D013035:Spasm / Q000000981:diagnostic imaging / Q000235:genetics* / Q000503:physiopathology