title: Lateral diffusion of membrane lipids and proteins is increased specifically in neurites of differentiating neuroblastoma cells.
abstract: Lateral diffusion of membrane lipids and proteins was determined in differentiating C1300 mouse neuroblastoma cells by fluorescence photo-bleaching recovery measurements. It is demonstrated that upon differentiation the lateral diffusion of membrane lipids and proteins is increased specifically in the extending neurites. This indicates the appearance of a topographical heterogeneity in the cell membrane, whereby more fluid domains become located in the membrane of the neurites.
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D002460:Cell Line; D003712:Dendrites / Q000648:ultrastructure*; D008563:Membrane Lipids / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism*; D051379:Mice; D009447:Neuroblastoma / Q000648:ultrastructure*; D013050:Spectrometry, Fluorescence
chemical_list: D008563:Membrane Lipids; D008565:Membrane Proteins