Familial achalasia of the esophagus in mother and son: a possible pathogenetic relationship.
Familial achalasia most often has been recorded in siblings, and only rarely (twice previously) in a parent and offspring. This report concerns a third case of achalasia in a parent and offspring (mother and son). Clinical and radiographic features of the esophageal achalasia are presented. The possibility that genetic factors may play a role in the etiology of this disorder is discussed.
D000368:Aged; D004931:Esophageal Achalasia / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000235:genetics*; D004945:Esophagoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography