title: Consequences of eyelid squeezing on intraocular pressure.
abstract: We investigated the effect of a forcible eyelid squeeze (two-second squeeze and two-second rest) over one minute, on intraocular pressure in volunteer groups of normal volunteers, ocular hypertensive and glaucoma patients, and those with a family history of glaucoma. The normal volunteers fell into two groups: responders and nonresonders, with the responders showing about a 2-mm Hg decrease and the nonresponders a small increase in intraocular pressure. It was possible to arrange the groups into an order dependent upon the change in intraocular pressure induced by eyelid squeezing; normal responders (-1.98 mm Hg), family history of glaucoma (-0.48 mm Hg), ocular hypertensive patients (-0.07 mm Hg), normal nonresponders (+ 0.04 mm Hg) and glaucoma patients (taking medication) (+ 0.25 mm Hg). Correlation of disease entity with other ocular factors such as intraocular pressure and total outflow facility was poor.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005143:Eyelids / Q000502:physiology*; D005260:Female; D005901:Glaucoma / Q000235:genetics / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged