title: Effects of heparin, aspirin and dipyridamole on thrombus formation on venous catheters.
abstract: Heparin, aspirin and dipyridamole were given alone or in combination to groups of sheep which had polyethylene catheters inserted into facial and saphenous veins. Animals were killed after 3 or 9 days. Neither aspirin nor dipyridamole reduced the amounts of thrombus on the catheters at autopsy. Heparin reduced thrombus only when sufficient was given to reduce blood coagulation.
mesh_terms: D000818:Animals; D001241:Aspirin / Q000627:therapeutic use*; D002404:Catheterization / Q000009:adverse effects*; D004176:Dipyridamole / Q000627:therapeutic use*; D004195:Disease Models, Animal; D005145:Face / Q000098:blood supply; D006493:Heparin / Q000627:therapeutic use*; D011095:Polyethylenes / Q000009:adverse effects; D012501:Saphenous Vein; D012756:Sheep; D013927:Thrombosis / Q000209:etiology / Q000517:prevention & control*; D014680:Veins
chemical_list: D011095:Polyethylenes; D004176:Dipyridamole; D006493:Heparin; D001241:Aspirin