[Carcinoma of the kidney. Trial of chemotherapy. 97 patients (author's transl)].
Chemotherapy for carcinoma of the kidney using the sequence VM 26 (or vincristine), CCNU gave 12 per cent of objective results (complete remission or regression of more than 50 per cent in metastatic tumours and did not alter the actuarial survival curve of these patients. The same type of chemotherapy given on a routine basis and early did not alter the actuarial curves of the first remission after nephrectomy for carcinoma of the kidney at Robson stage III or II. Early chemotherapy would thus not appear to be justified before trials in cases of metastatic carcinoma have led to the discovery of a more effective form.
D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000556:secondary; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy*; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009607:Nitrosourea Compounds / Q000008:administration & dosage* / Q000627:therapeutic use; D012075:Remission, Spontaneous; D014750:Vincristine / Q000008:administration & dosage* / Q000627:therapeutic use
D009607:Nitrosourea Compounds; D014750:Vincristine
Cancer du rein: essai de chimiothérapie. 97 malades.