Luteinizing hormone and follicle-stimulating hormone production in the pars tuberalis of hypophysectomized rats.
Luteinizing hormone and follicle-stimulating hormone were identified by immunocytochemistry in the same cells of the pituitary pars tuberalis, following hypophysectomy in the rat. A marked hyperplasia and hypertrophy of these cells occurred in response to hypophysectomy. These findings are discussed in light of the potential for hormone production by pars tuberalis gonadotropes following hypophysectomy performed as part of an experimental protocol, as well as that performed for palliation of human metstatic breast cancer.
D000818:Animals; D005260:Female; D005640:Follicle Stimulating Hormone / Q000096:biosynthesis*; D007016:Hypophysectomy; D007120:Immunochemistry; D007986:Luteinizing Hormone / Q000096:biosynthesis*; D010902:Pituitary Gland / Q000378:metabolism; D010903:Pituitary Gland, Anterior / Q000166:cytology / Q000378:metabolism*; D051381:Rats
D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone