[Radioimmunoassay of cholylglycine in serum (author's transl)].
Serum levels of cholylglycines (CG) were determined by radioimmunoassay and that of total bile acids (TBA) by enzymatic method. In normal subjects, serum levels of CG, TBA and CG/TBA ratio were 0.6 +/- 0.4 micronM, 7 +/- 2 micronM and 0.08 +/- 0.06, respectively. They were increased markedly in acute hepatitis and moderately in chronic hepatitis and cirrhosis. Thus, measurement of serum CG as compared with serum TBA appears to be a sensitive liver test.
D001647:Bile Acids and Salts / Q000097:blood; D006000:Glycocholic Acid / Q000097:blood*; D006505:Hepatitis / Q000097:blood*; D006801:Humans; D006913:Hydroxysteroid Dehydrogenases; D008103:Liver Cirrhosis / Q000097:blood*; D011863:Radioimmunoassay
D001647:Bile Acids and Salts; D006913:Hydroxysteroid Dehydrogenases; D006000:Glycocholic Acid