Endogenous prostaglandins modulate adrenal catecholamine secretion.
Adrenal catecholamine secretion induced by haemorrhage in the cat was increased by administration of indomethacin to intact or to bilaterally nephrectomized animals. Infusion of PGE2 (but not of PGF2 alpha) suppressed the increased catecholamine secretion caused by indomethacin.
D000311:Adrenal Glands / Q000378:metabolism*; D000818:Animals; D002395:Catecholamines / Q000378:metabolism*; D002415:Cats; D005260:Female; D007213:Indomethacin / Q000494:pharmacology; D008297:Male; D009392:Nephrectomy; D011453:Prostaglandins / Q000502:physiology*; D011458:Prostaglandins E / Q000494:pharmacology; D011460:Prostaglandins F / Q000494:pharmacology; D013997:Time Factors
D002395:Catecholamines; D011453:Prostaglandins; D011458:Prostaglandins E; D011460:Prostaglandins F; D007213:Indomethacin