The respiratory effects of 1-cis-2-(a-dimethylamino-m-hydroxybenzyl) cyclohexanol-HCl and pentazocine in man.
The respiratory effects of 1-cis-2-(a-dimethylamino-m-hydroxybenzyl) cyclohexanol-HCl (WY-15,705) were compared to those of pentazocine when given intramuscularly to man. It was found that WY-15,705 was 2.8 times as potent in terms of its respiratory depressant effects.
D000588:Amines / Q000494:pharmacology*; D000700:Analgesics / Q000494:pharmacology*; D001596:Benzylamines / Q000494:pharmacology*; D002245:Carbon Dioxide / Q000378:metabolism; D003511:Cyclohexanols / Q000494:pharmacology; D006801:Humans; D008297:Male; D010423:Pentazocine / Q000494:pharmacology*; D012119:Respiration / Q000187:drug effects*; D013997:Time Factors
D000588:Amines; D000700:Analgesics; D001596:Benzylamines; D003511:Cyclohexanols; D002245:Carbon Dioxide; C018273:ciramadol; D010423:Pentazocine