title: [Draize's test in assessment of eye tolerance to various cosmetic products].
abstract: The methods of Marzulli-Ruggles and Draize were used in an assessment of eye irritation on the part of three children's shampoos. Two products proved irritant with the Marzulli-Ruggles method. The most aggressive product was designated VAS-2-36/A. Better tolerance was observed in albino rabbits when the Draize method was used, though even here some ocular alterations were noted. Once again, VAS-2-36/A was the most irritant substance.
mesh_terms: D000818:Animals; D003228:Conjunctiva / Q000187:drug effects; D003315:Cornea / Q000187:drug effects; D004342:Drug Hypersensitivity; D005123:Eye / Q000187:drug effects; D005143:Eyelids / Q000187:drug effects*; D007498:Iris / Q000187:drug effects; D008722:Methods; D011817:Rabbits; D012915:Soaps / Q000009:adverse effects*
chemical_list: D012915:Soaps
vernacular_title: Tollerabilità oculare di taluni prodotti di cosmesi con il test di Draize.