title: Increase of serum cholesterol in man fed a bran diet.
abstract: The effects of wheat bran and other sources of dietary fibre on serum total and high density lipoprotein(HDL)-cholesterol were investigated in a group of 62 subjects, with rigid control of dietary intake. It was found that a high-fibre diet with vegetables and fruits as well as a low-fibre diet, to which isolated citrus pectin had been added to the same level as present in the vegetables and fruits diet, caused a small decrease in the concentration of serum cholesterol after 5 weeks. Surprisingly, addition of bran (on average 38 g/day) to a low-fibre diet caused an increase in the level of serum cholesterol by on average 0.34 mmol/l (P less than or equal to 0.005). The amount and type of dietary fibre had no substantial effect on the HDL-cholesterol concentration.
mesh_terms: D000293:Adolescent; D000328:Adult; D001939:Bread; D002482:Cellulose / Q000494:pharmacology*; D002784:Cholesterol / Q000097:blood*; D004043:Dietary Fiber / Q000494:pharmacology*; D005260:Female; D005638:Fruit; D006801:Humans; D008297:Male; D010368:Pectins / Q000494:pharmacology; D014908:Triticum; D014675:Vegetables
chemical_list: D004043:Dietary Fiber; D010368:Pectins; D002482:Cellulose; D002784:Cholesterol