[Two pathways of pyrimidine nucleotide biosynthesis in birds].
Dillerent chicken tissues are shown to display a clearly pronounced specificity relative to [2-14C] orotic acid and [5-3H]uridine as precursors of synthesis of the pool and RNA pyrimidine nucleotides. The fraction of pyrimidine nucleotides synthetized relative to the reserve pathway (uridine utilization) decreases in the series: kidneys greater than duodenum mucosa greater than lungs greater than liver greater than pancreas greater than bone marrow greater than brain greater than spleen. The results of [2-14C]orotic acid and [53H]uridine incorporation into UMP and CMP of the liver and spleen tissues RNA are interpreted in terms of the concept on existence of separate pools of pyrimidine phosphates--RNA precursors.
D000818:Animals; D002645:Chickens; D004386:Duodenum / Q000378:metabolism; D007413:Intestinal Mucosa / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D009928:Organ Specificity; D009963:Orotic Acid / Q000378:metabolism*; D011742:Pyrimidine Nucleotides / Q000096:biosynthesis*; D012313:RNA / Q000096:biosynthesis; D014529:Uridine / Q000378:metabolism*
D011742:Pyrimidine Nucleotides; D009963:Orotic Acid; D012313:RNA; D014529:Uridine
O dvukh putiakh biosinteza pirimidinovykh nukleotidov u ptits.