title: [Changes in the sensitivity of the heart of marine mollusks to acetylcholine during the spawning period].
abstract: In experiments on 5 species of marine bivalve molluscs (Spisula sachalinensis, Callista brevisiphonata, Mactra sulcatoria, Peronidia venulosa, Mya japonica) it has been shown that the level of sensitivity of cardiac muscle to ACh corresponds to functional condition of the reproductive system. During the discharge of mature sexual products, significant increase in the sensitivity to the mediator is observed -- from threshold ACh concentrations about 10(-9) M to 10(-15)--10(-17) M during spawning. If the spawning time is shifted, the onset of the increase in cardiac sensitivity is shifted as well. This parallelism is absent in species with portional mode of reproduction -- Crenomytilus grayanus and Modiolus difficilis.
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D002319:Cardiovascular System / Q000187:drug effects*; D008974:Mollusca / Q000502:physiology*; D012098:Reproduction; D013045:Species Specificity
chemical_list: D000109:Acetylcholine
vernacular_title: Ob izmenenii chuvstvitel'nosti serdtsa morskikh molliuskov k atsetilkholinu v period neresta.