title: Rapid melatonin transients.
abstract: Two normal male subjects exhibited rapid pulses of melatonin concentration in plasma, apparently unrelated to stages of sleep and undisturbed with spontaneous waking during the night. Pulse intervals of approximately 8 and 12 min., respectively, for subjects 1 and 2, were associated with excursions of 35% and 33% of the nadir or 28% and 26% of the mean value. The pulses were detected with a 2.5 min. sampling interval.
mesh_terms: D000328:Adult; D004569:Electroencephalography; D006801:Humans; D008297:Male; D008550:Melatonin / Q000097:blood / Q000378:metabolism*; D010507:Periodicity; D012894:Sleep Stages
chemical_list: D008550:Melatonin