Treatment of psoriasis with topical nitrogen mustard.
With the advent of various new methods of treating psoriasis, it is necessary to remind physicians to consider an agent that is easy to administer, locally effective, relatively inexpensive, not time-consuming and without systemic toxic effects. Nineteen patients were treated with topical nitrogen mustard between 1972 and 1976, and only five developed sufficient contact sensitization to warrant stopping medication.
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006801:Humans; D006854:Hydrocortisone; D008466:Mechlorethamine / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D011537:Pruritus / Q000139:chemically induced / Q000188:drug therapy; D011565:Psoriasis / Q000188:drug therapy*
D000893:Anti-Inflammatory Agents; D008466:Mechlorethamine; D011241:Prednisone; D006854:Hydrocortisone