title: Amebic liver abscess in children: clinical and epidemiologic features.
abstract: Amebiasis, that is, infection with Entameba histolytica, continues to be endemic in the United States, with liver abscess occurring as an infrequent but constant complication. Seven cases are reported, with epidemiologic investigation of two. Reliable findings in hepatic abscess include fever, abdominal pain, respiratory distress, tender abdomen, and large, tender liver. Anemia, elevated white count with left shift, and the radiographic findings of an elevated right hemidiaphragm are constant. Epidemiologically, amebiasis occurs in clusters in the United States with person-to-person transmission predominant in spread. Infection is associated with poor sanitation and crowding. Investigation of the families of two patients documented 9/21 carriers and an additional 3/21 who were seropositive, as well as crowding and poor sanitation. In this country, treatment of a patient with amebic disease should include investigation of his home and family.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008101:Liver Abscess, Amebic / Q000175:diagnosis / Q000235:genetics / Q000635:transmission; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D008800:Mexico / Q000208:ethnology; D008875:Middle Aged; D012499:Sanitation; D014481:United States
chemical_list: D008795:Metronidazole