title: [Principles for intensive therapy of status epilepticus in children].
abstract: A total of 113 children with brain edema of infectious and toxic nature were studied. The main clinical syndrome in these conditions was an epileptical status. Among anticonvulsive drugs used seduxen appeared to be the most effective. The use of GABA, gas narcosis and myorelaxants is recommended as well. The rehydration by plasma, low molecular plasma substitutes and glucose-polyion solutions are discussed. The paper contains some information on contraindications for early dehydration and rehydration. Hypoxia is eliminated by providing adequate lung ventilation, oxygenotherapy or hyperbaric oxygenation, by using oxidative enzymes and drugs increasing the resistance of the brain to hypoxia and hypothermia. It is recommended that hormonal therapy should be used. The techniques of urgent measures and their sequence are given.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000769:Anesthesia, Inhalation; D001803:Blood Transfusion; D001812:Blood-Brain Barrier; D002648:Child; D002675:Child, Preschool; D002697:Chloral Hydrate / Q000627:therapeutic use; D003975:Diazepam / Q000627:therapeutic use; D005440:Fluid Therapy; D006801:Humans; D006885:Hydroxybutyrates / Q000627:therapeutic use; D006982:Hypertonic Solutions / Q000008:administration & dosage; D007036:Hypothermia, Induced; D010100:Oxygen / Q000627:therapeutic use; D010949:Plasma; D013226:Status Epilepticus / Q000188:drug therapy / Q000628:therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D006885:Hydroxybutyrates; D006982:Hypertonic Solutions; D002697:Chloral Hydrate; D003975:Diazepam; D010100:Oxygen
vernacular_title: Printsipy intensivnoĭ terapii sudorozhnogo statusa u deteĭ.