Suppression of the desquamating effect of smoking on the human endothelium by hydroxyethylrutosides.
In a group of volunteers, smoking two cigarettes produced a significant increase in the number of circulating endothelial cells. This effect was suppressed in another group by a preventive oral administration of a hydroxyethylrutoside preparation. The results fully confirmed our earlier experimental findings in rats.
D002452:Cell Count; D004727:Endothelium / Q000187:drug effects / Q000473:pathology*; D005260:Female; D006801:Humans; D006896:Hydroxyethylrutoside / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D009538:Nicotine / Q000037:antagonists & inhibitors*; D012431:Rutin / Q000031:analogs & derivatives*; D012907:Smoking / Q000473:pathology*
D006896:Hydroxyethylrutoside; D012431:Rutin; D009538:Nicotine