Ascorbic acid biosynthesis in the mammalian kidney.
The egg-laying mammals (Prototheria) synthesize L-ascorbic acid only in kidney, as is characteristic of reptiles. Bandicoots (Marsupialia) synthesize it in both kidney and liver. 2 other species of marsupials (kangaroos) synthesize it primarily in liver, but some individuals also synthesize in kidney.
D000818:Animals; D001205:Ascorbic Acid / Q000096:biosynthesis*; D007668:Kidney / Q000378:metabolism*; D007783:Lactones; D008099:Liver / Q000378:metabolism; D008394:Marsupialia / Q000378:metabolism*; D009007:Monotremata / Q000378:metabolism*; D013045:Species Specificity; D013401:Sugar Alcohol Dehydrogenases / Q000378:metabolism
D007783:Lactones; D013401:Sugar Alcohol Dehydrogenases; D001205:Ascorbic Acid