[Basal prolactin secretion in diabetes mellitus].
Consideration given to the literature data about the diabetogenic effect of prolactin, the basal prolactin secretion was investigated in 98 patients with diabetes mellitus. A significantly increased basal prolactin level was established. The influence of age, sex, disease duration, type of diabetes, blood sugar level, mode of treatment and vascular complications upon prolactinemia was studied. Significantly higher prolactinemia was found in insulin treated patients and insignificantly -- in diabetics with retinopathy. The correlation of prolactinemia with glycemia, insulinemia and lipacidemia is low. That provides gounds to admit that hyperprolactinemia plays no essential role as an additional diabetogenic factor in the patients with diabetes mellitus. The causal relationship between hyperprolactinemia and diabetes still remains not well elucidated.
D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000503:physiopathology*; D003928:Diabetic Nephropathies / Q000503:physiopathology; D003930:Diabetic Retinopathy / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008593:Menopause; D008598:Menstruation; D011388:Prolactin / Q000097:blood / Q000378:metabolism*
D001786:Blood Glucose; D011388:Prolactin
Prouchvaniia vurkhu bazalnata sekretsiia na prolaktina pri bolni ot zakharna bolest.