[About the antimicrobial activity of substituted aromatic aldehydes and alcohols (author's transl)].
In the scope of our research about the antimicrobial activity of serveral chemicals a number of substituted benzaldehydes and benzylalcohols was investigated under standardized conditions following the method of DGHM (German Society of Hygiene and Microbiology) against bacteria, dermatophytes and moulds. The germicidal activity, demonstrated by the suspension test, is generally low except under special conditions (low or high pH-value). The germistatic activity, demonstrated by the MIC-test, is much higher than the germicidal effect (figs. 1--4). The relation structure-germistatic activity is discussed.
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001419:Bacteria / Q000187:drug effects*; D001547:Benzaldehydes / Q000494:pharmacology*; D001592:Benzyl Alcohols / Q000494:pharmacology*; D001593:Benzyl Compounds / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005658:Fungi / Q000187:drug effects*; D013045:Species Specificity; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001547:Benzaldehydes; D001592:Benzyl Alcohols; D001593:Benzyl Compounds
Zur antimikrobiellen Wirksamkeit substituierter aromatischer Aldehyde und Alkohole.