[Mechanism of the change in energy and electrolyte metabolism in the respiratory musculature in experimental botulism].
Distinct decrease in concentrations of creatine phosphate and K+ was observed in various respiratory muscles of cat in generalized botulism, accompanied by the syndrom of asphyxia. Content of glycogen and Na+ was unaltered in these cases. In local botulinic paralysis concentrations of creatine phosphate, glycogen and K+ were decreased in the respiratory muscles. Accumulation of Na+ was observed in diaphragm and intercostal muscles. Content of K+ and creatine phosphate was partially restored in respiratory muscles after intraperitoneal administration of guanidine HCl/50 mg/kg of body weight/.
D000818:Animals; D001906:Botulism / Q000378:metabolism*; D002415:Cats; D003964:Diaphragm / Q000378:metabolism; D004734:Energy Metabolism; D005260:Female; D006003:Glycogen / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000378:metabolism*; D010725:Phosphocreatine / Q000378:metabolism; D011188:Potassium / Q000378:metabolism*; D012119:Respiration; D012272:Ribs; D012964:Sodium / Q000378:metabolism*; D013997:Time Factors
D010725:Phosphocreatine; D006003:Glycogen; D012964:Sodium; D011188:Potassium
K mekhanizmu izmeneniia énergeticheskogo i élektrolitnogo obmena v dykhatel'noĭ muskulature pri éksperimental'nom botulizme.