The effect of sympathomimetic drugs on immediate skin reactions and metabolic responses in asthmatic patients.
The varied effects of intradermal injection of isoproterenol and propranolol on the immediate skin reaction were studied in relation to the metabolic responses to the intravenous injection of epinephrine. In asthmatic patients whose skin reaction was not suppressed with 10(-7) M isoproterenol, the hyperglycemic response after the injection of epinephrine was significantly reduced.
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000276:immunology / Q000378:metabolism*; D001786:Blood Glucose; D004391:Dust; D004837:Epinephrine / Q000008:administration & dosage; D005230:Fatty Acids, Nonesterified; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D007545:Isoproterenol / Q000008:administration & dosage; D008297:Male; D011433:Propranolol / Q000008:administration & dosage; D012882:Skin Tests; D013566:Sympathomimetics / Q000008:administration & dosage*
D001786:Blood Glucose; D004391:Dust; D005230:Fatty Acids, Nonesterified; D013566:Sympathomimetics; D011433:Propranolol; D007545:Isoproterenol; D004837:Epinephrine