[Intestinal resorption with 3H labeled enzyme mixture (wobenzyme)].
0.2 g of an enzyme mixture (Wobenzym) labelled with 3H-acetic anhydride, were given orally to guinea pigs, which were arranged in 4 groups of 5 animals. The animals of each group were sacrificed at intervals of 30 minutes, 2, 4 and 24 hours after application. Radioactivity of the small and large intestine, plasma, urine, liver, heart, kidney, and skeletal muscle were determined. It could be shown that the labelled mixture of enzymes was absorbed from the intestine and was demonstrable in significant amounts in plasma, urine, heart, kidney, liver and skeletal muscle.
D000818:Animals; D004338:Drug Combinations; D004798:Enzymes / Q000097:blood / Q000652:urine; D006168:Guinea Pigs; D006867:Hydrolases / Q000378:metabolism*; D007408:Intestinal Absorption; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D009132:Muscles / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D012431:Rutin / Q000378:metabolism; D014018:Tissue Distribution; D014316:Tritium
D004338:Drug Combinations; D004798:Enzymes; D014316:Tritium; D012431:Rutin; C023295:Wobenzym; D006867:Hydrolases
Untersuchungen über intestinale Resorption mit 3H-markiertem Enzymgemisch (Wobenzym).