[The toxoplasmin skin test (st) - a safe method to reveal endured contact with toxoplasma gondii? (author's transl)].
Toxoplasmin skin tests were applied to 4.341 pregnant women, between August 1975 and December 1977, and 30 per cent of them were serologically tested by means of DT and FR. Findings were in fair agreement in 87 per cent of all cases. This result was compared to similar examinations conducted earlier in the past. Discrepancies in excess of 30 per cent were quoted elsewhere in literature. Possible causes are discussed in greater detail. - A clearcut correlation was found to exist between the intensity of dermal response to toxoplasmin skin tests and agreement between such tests, on the one hand, and serological results, on the other. That agreement, remarkably, followed a linear correlation with the age of the pregnant women concerned. The gaps between responses widened along with decreasing age. - Differences between negative ST and serological tests were recorded from as much as 27 per cent. In such cases, serological confirmation should be sought immediately. Serological verification is considered to be essential to all poor positive responses to ST, defined by the author as erythema of the skin below 10 mm in diameter, where the discrepancy figure had been nearly 28 per cent. The amount of agreement regarding skin responses above 10 mm in diameter was 98.6 per cent, an acceptable magnitude. - With all the above limitations, ST is an uninvolved and inexpensive screening method by which to detect endured toxoplasmosis. It is, therefore, suitable for proper selection, particularly at the beginning of pregnancy.
D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D012698:Serologic Tests; D012882:Skin Tests / Q000592:standards*; D014121:Toxoids; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis / Q000175:diagnosis*
D014121:Toxoids
Ist-der Toxoplasmin-Hauttest (IDT) eine sichere Methode zum Nachweis eines stattgehabten Kontaktes mit Toxoplasma gondii?