Inhibition of sterol biosynthesis by 9 alpha-fluoro and 9 alpha-hydroxy derivatives of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one.
D000818:Animals; D002478:Cells, Cultured; D002782:Cholestenes / Q000494:pharmacology*; D002783:Cholestenones / Q000138:chemical synthesis / Q000494:pharmacology*; D005227:Fatty Acids / Q000096:biosynthesis; D005333:Fetus; D006903:Hydroxymethylglutaryl CoA Reductases / Q000378:metabolism; D007739:L Cells / Q000187:drug effects / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D051379:Mice; D013259:Steroids, Fluorinated / Q000138:chemical synthesis / Q000494:pharmacology*; D013261:Sterols / Q000096:biosynthesis*; D013329:Structure-Activity Relationship
D002782:Cholestenes; D002783:Cholestenones; D005227:Fatty Acids; D013259:Steroids, Fluorinated; D013261:Sterols; D006903:Hydroxymethylglutaryl CoA Reductases