The effects of repeated injections of adrenaline on the response of the fowl to further alarm stimulation.
Chicks, aged two weeks, were injected with either adrenaline (300 microgram/kg) or saline daily for seven days. One day after the seventh injection it was found that the birds treated with adrenaline had become hypolipacidaemic and hypocholesteraemic and that there had been adrenal hypertrophy and an increase in the adrenal store of cholesterol. Plasma concentrations of glucose and corticosterone were within the normal range. The two groups (adrenaline- or saline-treated) were further subdivided each into two subgroups and were now injected with either adrenaline or saline, and their responses measured over a 120 min period. A significantly shorter period of hyperglycaemia was found in the birds pretreated with adrenaline and given a further injection of the hormone. These birds also showed an enhanced lipacidaemic response but the corticosterone response was not altered.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D002645:Chickens / Q000097:blood / Q000502:physiology*; D002784:Cholesterol / Q000097:blood; D003345:Corticosterone / Q000097:blood; D004837:Epinephrine / Q000008:administration & dosage* / Q000494:pharmacology; D005230:Fatty Acids, Nonesterified / Q000097:blood; D007273:Injections, Intramuscular; D013312:Stress, Physiological / Q000662:veterinary*
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D002784:Cholesterol; D003345:Corticosterone; D004837:Epinephrine