title: [Effect of teratogens on the functional state of the lysosomal segregation apparatus of embryonic hepatocytes].
abstract: The effect of chloridine, 2-mercaptobenzimidazol, 6-mercaptopurine, dichlorhydrate 2(beta-ethyl aminoethyl) pyridine, pentoxyl, actinomycin D and dimethyl sulfoxide on the functional state of lysosome-segregation system (red acridine granules) was studied in drugs to stabilize the lysosome membrane in the embryonic cells is proved on the basis of experiments with quenching the acridine orange granules adsorbed by the structures with the neutral red molecules.
mesh_terms: D000818:Animals; D002463:Cell Membrane Permeability / Q000187:drug effects; D005260:Female; D005865:Gestational Age; D007425:Intracellular Membranes / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000196:embryology*; D008247:Lysosomes / Q000187:drug effects*; D008856:Microscopy, Fluorescence; D011247:Pregnancy; D051381:Rats; D013723:Teratogens / Q000494:pharmacology*
chemical_list: D013723:Teratogens
vernacular_title: Vliianie nekotorykh teratogenov na funktsional'noe sostoianie lizosomno-segregatsionnogo apparata émbrional'nykh gepatotsitov.