Factor IX deficiency in an Alaskan Malamute.
Factor IX deficiency, consistent with hemophilia B, was detected in a 6-month old male Alaskan Malamute with a 2-week history of persistent oozing from an oral wound. Laboratory studies disclosed an intrinsic coagulation defect. Hemophilia A was initially suspected. Further evaluation demonstrated normal factor VIII activity and factor VIII-related antigen, but factor IX activity was only 1.3% of normal.
D000413:Alaska; D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis*; D004285:Dogs; D006467:Hemophilia A / Q000175:diagnosis / Q000662:veterinary; D002836:Hemophilia B / Q000175:diagnosis / Q000662:veterinary*; D008297:Male