In vivo detection of rabbit atropinesterase.
The comparability of an in vivo rapid screening test for the presence of atropinesterase with an in vitro standard colorimetric test was assessed using 410 male and female New Zealand white rabbits. The results from both tests were in agreement in 405 of the 410 (98.8%) rabbits compared. One false negative and four false positive results occurred with the rapid screening test.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002265:Carboxylic Ester Hydrolases / Q000097:blood*; D003124:Colorimetry; D005260:Female; D008297:Male; D011817:Rabbits / Q000097:blood*; D012025:Reflex, Pupillary / Q000187:drug effects
D001285:Atropine; D002265:Carboxylic Ester Hydrolases; C023201:tropinesterase