title: Reflex threshold shift in chinchillas following a prolonged exposure to noise.
abstract: The acoustic reflex is considered to reduce transmission across the middle ear and thereby protect the inner ear from intense sounds. The dynamic properties of this reflex seem to be a function of the duration of the eliciting stimulus. Assessment of the protective action afforded by middle-ear muscle contractions for long-term noise exposures requires the knowledge of how these dynamic properties change under such conditions. Round window electrodes were implanted in eight chinchillas. Changes in the threshold of the acoustic reflex were measured during an eight-hour exposure at 95 dB SPL to an octave-band noise centered at 0.5 kHz. The criterion measure of the acoustic reflex was a change in the amplitude of the cochlear microphonic generated by a 0.5 kHz eliciting tone. Thresholds of the acoustic reflex increased systematically throughout the noise exposure up to approximately 14 dB after 8 hours. The time course of the changes in the threshold of the acoustic reflex was nearly identical to the time course of behaviorally measured changes in the auditory sensitivity as reported by Carder and Miller (1972).
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000818:Animals; D001305:Auditory Fatigue; D002682:Chinchilla; D003055:Cochlear Microphonic Potentials; D009622:Noise / Q000009:adverse effects*; D012022:Reflex, Acoustic; D013997:Time Factors