[Effectiveness of antifibrinolytic, edema-preventing and hypotensive agents in the prevention of recurrent bleeding from intracranial aneurysms].
On the basis of a material of 561 patients with ruptured intracranial aneurysms treated at the Department of Neurosurgery, Institute of Neurology, Medical Academy in Cracow in the years 1971 to 1977 the authors discuss the effectiveness of conservative treatment for prevention of recurrent bleeding from these aneurysms. The whole group of 561 patients were divied into two subgroups: 361 patients (group A) receiving standard antifibrilytic treatment, drugs preventing oedema formation and reducing the arterial blood pressure, and 254 patients (group B) who were not given antifibrinolytic agents and the other pharmacological agents were given to them only sporadivally. Recurrent bleeding developed in 8.86% of cases of group A and 11.02% in group B. The difference was not significant.
D000328:Adult; D000614:Aminocaproates / Q000627:therapeutic use*; D015119:Aminocaproic Acid / Q000627:therapeutic use*; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001929:Brain Edema / Q000517:prevention & control*; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications*; D008875:Middle Aged; D012008:Recurrence; D012421:Rupture; D013345:Subarachnoid Hemorrhage / Q000188:drug therapy* / Q000209:etiology
D000614:Aminocaproates; D000959:Antihypertensive Agents; D015119:Aminocaproic Acid
Skuteczność leków antyfibrynolitycznych, przeciwobrzekowych i hipotensyjnych w zapobieganiu nawrotom krwawienia z tetniaków mózgu.