[Myocardial damage in hemorrhagic hypotension].
Damage to the myocard caused by the loss of blood was studied in experiments on dogs. After long-lasting hypotonia focal lesions of the myocard of degenerative type have been found. Desorganization of the myofilaments and invagination of the disc could be seen in the area of the intercalar discs. Filaments in the other regions have not shown any alterations. In the mitochondria hypoxic lesions were revealed. One part of the alterations are not reversible. After 48 hours of survival focal necrosis with hyper contraction and calcification could be observed. It was surrounded by cellular infiltration containing mononuclear cells. Cellular necrosis revealed, may lie on the basis of the central lesion of the circulation appearing after long-lastng hypotonia.
D000818:Animals; D009202:Cardiomyopathies / Q000209:etiology*; D004285:Dogs; D005260:Female; D006470:Hemorrhage / Q000150:complications*; D008297:Male; D008931:Mitochondria, Muscle / Q000648:ultrastructure; D009206:Myocardium / Q000648:ultrastructure; D012771:Shock, Hemorrhagic / Q000150:complications
Myocardiális károsodások véreztetéses hypotoniában.