[Hemoperfusion with XAD-4 resin in the treatment of a severe parathion intoxication (author's transl)].
After ingestion of 200-300 ml E 605-forte (i.e., 100-150 g parathion) a maximal concentration of 10.2 mg/l could be measured in the plasma of a male patient. An extracorporeal hemoperfusion was carried out using XAD-4 resin. The clearance valued 83 ml/min at a blood flow of 100 ml/min, which is about 40% higher compared to perfusion on activated charcoal. The described method is possibly an improved technique which could raise the rate of survival following parathion intoxication. In our study, however, the fatal end could not be prevented due to the intake of a very high dose of the poison.
D002606:Charcoal; D006464:Hemoperfusion; D006801:Humans; D007475:Ion Exchange Resins; D008297:Male; D008875:Middle Aged; D010278:Parathion / Q000097:blood / Q000378:metabolism / Q000506:poisoning*; D013405:Suicide; D014018:Tissue Distribution
D007475:Ion Exchange Resins; D002606:Charcoal; D010278:Parathion
Hämoperfusion mit Adsorberharz XAD-4 bei einer extrem schweren Parathion-Vergiftung.