title: Reference compounds for the study of moxestrol metabolism.
abstract: Reference compounds for the subsequent identification of the metabolites of the potent estrogen, moxestrol (R 2858) , in various species were isolated from the bile of phenobarbital pretreated rats or obtained via enzymatic hydroxylation by microorganisms. A few of them were prepared by chemical synthesis. The structures of all these compounds were determined by physical and chemical methods.
mesh_terms: D000818:Animals; D001646:Bile / Q000032:analysis; D055598:Chemical Phenomena; D002621:Chemistry; D045166:Estradiol Congeners / Q000138:chemical synthesis* / Q000378:metabolism; D004997:Ethinyl Estradiol / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism; D005874:Gibberella / Q000378:metabolism; D006900:Hydroxylation; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats
chemical_list: D045166:Estradiol Congeners; D004997:Ethinyl Estradiol; C011310:moxestrol; D010634:Phenobarbital