title: Analysis of the cores of asbestos bodies from members of the general population: patients with probable low-degree exposure to asbestos.
abstract: Asbestos bodies were isolated from the lungs of 21 patients who had 300 to 9,000 of such bodies/g of lung tissue, a concentration frequently found in manual laborers in the general population who are not primary asbestos workers. All of the 123 bodies examined by electron diffraction produced diffraction patterns consistent with amphibole varieties of asbestos. Electron microprobe analysis (energy dispersive x-ray spectroscopy) of 46 bodies revealed that 38 of the cores were composed of the commercial amphiboles, amosite and crocidolite, whereas only 8 were composed of the noncommercial amphiboles, anthophyllite and tremolite. Review of the occupations of these patients revealed that all but one had blue-collar jobs. For many of these persons, putative sources of asbestos exposure such as construction work could be defined, but for some, the source could not be determined. One woman was apparently exposed to asbestos in the practice of her hobby of ceramics, in which she used anthophyllite-contaminated clay. We concluded that commercial amosite/crocidolite asbestos forms the cores of most asbestos bodies in manual laborers in the general population and that the source is usually occupational.
mesh_terms: D000328:Adult; D000368:Aged; D001194:Asbestos / Q000032:analysis*; D001195:Asbestosis / Q000473:pathology*; D004577:Electron Probe Microanalysis; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008168:Lung / Q000032:analysis* / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009790:Occupations
chemical_list: D001194:Asbestos