[Corticosteroid-sensitive chemical diabetes in Horton's disease].
We report 5 cases of temporal arteritis associated with a diabetes whose good evolution under corticotherapy suggests a common pathogenesis. Several hypotheses can be formulated to explain the origin of the glycemic abnormality and to understand the way corticotherapy is effective. A moderate posology could at first have a hyperplasic effect on the insulin-secreting cells, and later on a favorable action on the vascular lesion and on an immunological disorder. Any definitive conclusion cannot be evolved yet. Only a more systematical study of the glycoregulation's abnormalities in the temporal arteritis will enable to answer the many remaining questions.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000368:Aged; D000818:Animals; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications* / Q000378:metabolism; D006168:Guinea Pigs; D006801:Humans; D007328:Insulin / Q000097:blood
D000305:Adrenal Cortex Hormones; D007328:Insulin
Diabète chimique cortico-sensible au cours de la maladie de Horton.