[Enzyme profile of exudate leukocytes from diabetic rabbits].
In leukocytes of exudate from diabetic rabbits, the activities of hexokinase, phosphoglucomutase and glucose-6-phosphate dehydrogenase are increased, and a tendency of adenylate kinase activity to decline is observable. The activities of UDP-pyrophosphatase, UDP-glycogentransferase, 6-phosphogluconate dehydrogenase and glutahione reductase in the exudate erythrocytes in diabetes are not essentially altered. The decrease of the key enzymes of glycolysis and pentose phosphate cycle, providing the leukocytes with energy and metabolites, reduces the functional activity of leukocytes from exudate in diabetes.
D000263:Adenylate Kinase / Q000097:blood; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology*; D004912:Erythrocytes / Q000201:enzymology; D005954:Glucosephosphate Dehydrogenase / Q000097:blood; D005964:Glucosyltransferases / Q000097:blood; D005980:Glutathione Reductase / Q000097:blood; D006593:Hexokinase / Q000097:blood; D007962:Leukocytes / Q000201:enzymology*; D010733:Phosphoglucomutase / Q000097:blood; D010734:Phosphogluconate Dehydrogenase / Q000097:blood; D011755:Pyrophosphatases / Q000097:blood; D011817:Rabbits
D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D005980:Glutathione Reductase; D005964:Glucosyltransferases; D006593:Hexokinase; D000263:Adenylate Kinase; D011755:Pyrophosphatases; D010733:Phosphoglucomutase
Enzimaticheskii prophil leukotsitov eksudata pri diabete.