[Measurement of multiregional blood volumes: a cerebral vascular autoregulatory phenomenon (author's transl)].
The variations in regional cerebral blood volume (RCBV) during controlled severe hypotension induced by sodium nitroprusside were studied in a series of 29 patients with aneurysms (14), meningiomas (6) and arteriovenous malformations. Two characteristic variations were noted. The RCBV and mean blood pressure (MPB) vary inversely, this type of variation being known as "Active variation". When pathological lesions are present the RCBV and MBP are modified in the same direction in the regions affected and this is called "Passive variation". A quantitative study in 21 patients showed that in the healthy regions there was a change from the active to the passive mode of variation for a MBP situated between 44 and 52 mm of mercury.
D000328:Adult; D000368:Aged; D001794:Blood Pressure; D001811:Blood Volume Determination; D002560:Cerebrovascular Circulation / Q000187:drug effects; D006801:Humans; D002532:Intracranial Aneurysm / Q000503:physiopathology*; D002538:Intracranial Arteriovenous Malformations / Q000503:physiopathology*; D008577:Meningeal Neoplasms / Q000503:physiopathology*; D008579:Meningioma / Q000503:physiopathology; D008875:Middle Aged; D008954:Models, Biological; D009599:Nitroprusside / Q000494:pharmacology
D009599:Nitroprusside
Mesure du volume sanguin multi-régional: phénomène d'autorégulation vasculaire cérébral.