title: [Total and specific IgE concentrations for early diagnosis of respiratory allergy in children less than four years old (author's transl)].
abstract: Serum total IgE concentrations were determined according to paper-radio-immunosorbent test (Prist, Phadebas) in 73 infants aged 2 months to 4 years, with recurrent asthmatoid bronchitis. Specific IgE against multiple inhalant allergens (Dermatophagoides pteronyssinus d1, house dust h3, pollens, moulds) were quantified by radio allergosorbent test (Rast, Phadebas). Normal total IgE values were determined in a control group of 111 infants aged 0 to 4 years. Total IgE were slightly elevated in 8 cases, strongly in 35 cases (id. e in 47% of the patients' group). Serum IgE are significantly higher in infants whose first degree relatives are atopics. Specific IgE against d1 are detected in 44% of our cases. Fourteen infants with dl-specific IgE have had an "ecologic treatment" by Paragerm AK. The clinical results are good in twelve of these patients. Total IgE and d1-specific IgE decrease in 5 cases at the end of the Paragerm application.
mesh_terms: D000367:Age Factors; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis / Q000276:immunology; D007073:Immunoglobulin E / Q000032:analysis*; D007223:Infant; D008297:Male; D011852:Radioallergosorbent Test; D012130:Respiratory Hypersensitivity / Q000175:diagnosis* / Q000276:immunology
chemical_list: D007073:Immunoglobulin E
vernacular_title: Intérêt du dosage des IgE totales et spécifiques dans le diagnostic précoce de l'allergie respiratoire chez l'enfant de moins de 4 ans.