Cell culture studies in progeria. I. Establishment and partial characterization of a lymphoblastoid cell line.
A lymphoblastoid cell line (EKS-L44) with definitive HLA specificities (HLA-Aw24, w30, B14, w35, Cw4-, DRw4, 5) was established from peripheral blood cells of a patient with progeria using Epstein-Barr virus. Cytogenetic study indicated that EKS-L44 was diploid after four months in vitro. The growth pattern of this cell line was not significantly different from a similarly established normal control nor from other lines initiated from patients with various disorders.
D002460:Cell Line; D002648:Child; D004171:Diploidy; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D008214:Lymphocytes / Q000166:cytology*; D008297:Male; D011371:Progeria / Q000473:pathology*
D006680:HLA Antigens