Viability of red cells stored in diminished concentration of citrate.
A comparison was made between the post-transfusion survival of red cells stored in standard ACD-A and in modified ACD-A, containing two-thirds the amount of citrate. Measurements of survival after 28 d storage in both solutions were made in each of six subjects. Mean post-transfusion survival with the two solutions was almost identical. When the results in one subject in whom survival was particularly bad with both solutions were omitted mean values at 24 h were 74.0% for standard ACD-A and 74.9% for modified ACD-A. It is concluded that viability is just as well maintained in modified ACD-A as in standard ACD-A. The results also provide further evidence of large differences between donors with respect to the maintenance of red cell viability during storage.
D000255:Adenosine Triphosphate / Q000097:blood; D001793:Blood Preservation; D002951:Citrates; D004905:Erythrocyte Aging; D006801:Humans; D008297:Male; D013997:Time Factors
D002951:Citrates; D000255:Adenosine Triphosphate