[Genetic polymorphism of erythrocytic enzymes in the Rennes area. Frequency of adenylate kinase, esterase D, adenosine deaminase, 6-phosphogluconate dehydrogenase, glutamate-pyruvate transaminase and glyoxyalase I phenotypes].
Blood donors from the Centre Régional de Transfusion Sanguine de Rennes were investigated for the phenotypic distribution of seven enzymatic systems : adenylate kinase, adenosine deaminase, esterase D, 6-phosphogluconate dehydrogenase, glutamate-pyruvate transaminase, phosphoglucomutase, and glyoxalase I. Two unusual phenotypes were observed: phenotype 6-1 for adenosine deaminase and phenotype 3-1 for transaminase GPT. For five of these enzymes, the statistical analysis points out significant differences in one or several of the European populations described in the literature.
D000243:Adenosine Deaminase / Q000235:genetics; D000262:Adenylyl Cyclases / Q000235:genetics; D000293:Adolescent; D000328:Adult; D000410:Alanine Transaminase / Q000235:genetics; D004912:Erythrocytes / Q000201:enzymology*; D004950:Esterases / Q000235:genetics; D005260:Female; D005602:France; D006801:Humans; D007791:Lactoylglutathione Lyase / Q000235:genetics; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D010733:Phosphoglucomutase / Q000235:genetics; D010734:Phosphogluconate Dehydrogenase / Q000235:genetics; D011110:Polymorphism, Genetic
D010734:Phosphogluconate Dehydrogenase; D000410:Alanine Transaminase; D004950:Esterases; D000243:Adenosine Deaminase; D007791:Lactoylglutathione Lyase; D000262:Adenylyl Cyclases; D010733:Phosphoglucomutase
Etude du polymorphisme génétique de quelques enzymes érythrocytaires dans la région de Rennes. Fréquence des phénotypes de l'adénylate-kinase, de l'estérase D, de l'adénosine-désaminase, de la 6-phosphogluconate-déshydrogénase, de la glutamate-pyruvate-transaminase et de la glyoxalase I.