Tumor location detected with radioactively labeled monoclonal antibody and external scintigraphy.
Murine teratocarcinomas were located in mice by external gamma-ray scintigraphy with an iodine-125-labeled monoclonal antibody specific to the tumors. The specificity of the method was increased by subtracting the radiation produced by an iodine-125-labeled indifferent monoclonal antibody of the same immunoglobulin class as the tumor-specific antibody.
D000818:Animals; D000912:Antibodies, Neoplasm; D002999:Clone Cells / Q000276:immunology; D051379:Mice; D009374:Neoplasms, Experimental / Q000175:diagnosis / Q000276:immunology; D011877:Radionuclide Imaging / Q000379:methods*; D013724:Teratoma / Q000175:diagnosis* / Q000276:immunology
D000912:Antibodies, Neoplasm