Leucocyte-like motility of cancer cells, with reference to the mechanism of extravasation in metastasis.
The movement of rat ascites tumor cells of AH66F and Yoshida sarcoma cultured in an agar medium was analyzed. Contraction occurred at the frontal fringe of each cell, and the cytoplasm and nucleus seemed to pass through the site of contraction. Morphological changes observed were similar to that of the leucoycte.
D000818:Animals; D002465:Cell Movement; D002478:Cells, Cultured; D007962:Leukocytes / Q000166:cytology; D008114:Liver Neoplasms, Experimental / Q000473:pathology; D009040:Motion Pictures; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis / Q000473:pathology; D051381:Rats; D012517:Sarcoma, Yoshida / Q000473:pathology