title: Polyvinylpyrrolidone contrast enhancement: abscess imaging.
abstract: Rabbits with thigh abscesses received an intravenous solution of polyvinylpyrrolidone (PVP) and metallic salts, resulting in a dense ring of contrast enhancement as determined by computed tomography (CT). Enhancement increased during the first two weeks, stabilized, then decreased to control levels at eight weeks. After antibiotics the ring of enhancement appeared to mark the abscess perimeter as it regressed. Normal muscle density did not change. The magnitude and duration of enhancement would improve CT detection of small lesions and be useful in evaluating the efficacy of therapy.
mesh_terms: D000038:Abscess / Q000000981:diagnostic imaging* / Q000188:drug therapy; D000818:Animals; D011205:Povidone; D011817:Rabbits; D011856:Radiographic Image Enhancement; D013848:Thigh; D014057:Tomography, X-Ray Computed
chemical_list: D011205:Povidone