title: [Forensic aspects of digoxin-poisoning: toxicological and morphological findings (author's transl)].
abstract: Case report. A 82 year old woman died 80 min after accidental ingestion of 5 mg beta-methyl-digoxin. The autopsy and the histological examination revealed non-specific alterations due to shock and preexisting coronary heart disease. Digoxin levels in various fluids and tissues were estimated by radioimmunoassay: bloodplasma 20--25 ng/ml, liquor 10--13 ng/ml, liver 100--110 ng/g, kidney 130--145 ng/g; the gastric fluid contained 0,6 mg. Forensic aspects of glycosid-intoxication, especially of the varying concentrations in different tissues, are discussed.
mesh_terms: D000368:Aged; D004077:Digoxin / Q000031:analogs & derivatives*; D005260:Female; D005554:Forensic Medicine; D006321:Heart / Q000187:drug effects; D006801:Humans; D008168:Lung / Q000187:drug effects / Q000473:pathology; D008520:Medigoxin / Q000032:analysis / Q000506:poisoning*; D009206:Myocardium / Q000473:pathology; D011863:Radioimmunoassay; D014018:Tissue Distribution
chemical_list: D004077:Digoxin; D008520:Medigoxin
vernacular_title: Toxikologische und morphologische Befunde bei Digosinvergiftung in forensischer Sicht.