In vitro dissolution of human gallstones: the efficacy of heparinized solutions.
The use of heparinized solutions to dissolve or fragment stones retained in the biliary tree after surgery is still controversial. In this in vitro study heparin in concentrations of up to 100,000 mu/l did not dissolve or fragment the stones examined, nor did it enhance the dissolution properties of the bile salt, sodium cholate.
D002769:Cholelithiasis / Q000188:drug therapy*; D002793:Cholic Acids / Q000627:therapeutic use; D004357:Drug Synergism; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D066298:In Vitro Techniques
D002793:Cholic Acids; D006493:Heparin