[Value of lymphoblastic transformation test for diagnosis and treatment of microbial asthmas in adults (author's transl)].
A lymphoblastic transformation test (LTT) done on 9 germs in 30 patients (270 tests) with bacterial asthma was found positive 117 times out of 170 (43.3%) while the same study done on a control group of 100 non microbial asthma was generally negative (5% of positive responses). Positive LTT confirmed, in 59.2% of cases, the cutaneous tests. In the other cases, discrepancies can be found in both ways: positive LTT and negative cutaneous tests (16.9%) or the reverse (23.9%). The significance of disagreeing results is discussed. Specific desensitizations done only with the bacteria producing agreeing positive reactions, gave interesting though inconstant results.
D000328:Adult; D001249:Asthma / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D001419:Bacteria / Q000276:immunology*; D003888:Desensitization, Immunologic; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000628:therapy; D008213:Lymphocyte Activation; D008297:Male; D012882:Skin Tests
Apport du test de transformation lymphoblastique au diagnostic et au traitement des asthmes bactériens de l'adulte.