Mercaptide chelated protoheme: a model compound for cytochrome P-450.
A mercaptide chelated heme having the spectral characteristics of cytochrome P-450 has been prepared by coupling di-3-amino-propyl-disulfide to protoheme, followed by reduction and disulfide cleavage with sodium dithionithe.
D002248:Carbon Monoxide; D055598:Chemical Phenomena; D002621:Chemistry; D003577:Cytochrome P-450 Enzyme System; D004121:Dimethyl Sulfoxide; D004220:Disulfides; D004227:Dithionite; D006418:Heme; D008954:Models, Biological; D013053:Spectrophotometry; D013438:Sulfhydryl Compounds
D004220:Disulfides; D013438:Sulfhydryl Compounds; D004227:Dithionite; D006418:Heme; D002248:Carbon Monoxide; D003577:Cytochrome P-450 Enzyme System; D004121:Dimethyl Sulfoxide