title: Development of tonic immobility in the rabbit: relation to body temperature.
abstract: Tonic immobility was studied in rabbit pups varying in age from 1 to 30 days. During the 1st 2 postnatal weeks the rabbits were active in an open field, had difficulty walking and executing a righting response, lost body temperature rapidly, and had no, or only short durations of, tonic immobility. After this age they were less active, hopped and righted well, maintained core temperature, and showed increased durations of tonic immobility. Within the 1st 2 postnatal weeks cooling and warming potentiated; thereafter, cooling disrupted and only warming potentiated tonic immobility. The results suggest that rate of heat loss can act as a stimulus to block tonic immobility and increase activity in neonatal rabbits. With development, cooling produces shivering which can disrupt tonic immobility, whereas warming may raise movement initiation thresholds which can potentiate tonic immobility.
mesh_terms: D000367:Age Factors; D000818:Animals; D001831:Body Temperature; D005106:Exploratory Behavior; D005260:Female; D007103:Immobilization; D008297:Male; D009043:Motor Activity; D009048:Motor Skills; D009129:Muscle Tonus; D011187:Posture; D011817:Rabbits; D012018:Reflex