Structure specificity of some immunoadjuvant synthetic glycopeptides.
The immunoadjuvant activity of muramyl dipeptide seems to be critically dependent on the type of substitution of the gamma-carboxyl group of the D-isoglutamine residue. Moreover the nonapeptide L-Ala-D-isoGlu-L-lys-D-Ala-(Gly)5-OME also shows a definite effect.
D000276:Adjuvants, Immunologic; D000818:Animals; D006020:Glycopeptides; D006168:Guinea Pigs / Q000276:immunology; D006968:Hypersensitivity, Delayed; D010047:Ovalbumin; D013329:Structure-Activity Relationship
D000276:Adjuvants, Immunologic; D006020:Glycopeptides; D010047:Ovalbumin