title: Gonadotrophin-inhibiting activity in seminal plasma from intact and vasectomized bulls.
abstract: Bull seminal plasma administered to male rats at the time of castration inhibited the rise in the levels of FSH and LH otherwise seen in the serum 24 h later. That the gonadotrophin-inhibiting activity was also present in the seminal plasma from vasectomized bulls suggests that it was not of testicular origin. Although the substance with gonadotrophin-inhibiting activity was a protein, it may be chemically distinct from inhibin.
mesh_terms: D000818:Animals; D002417:Cattle; D005640:Follicle Stimulating Hormone / Q000037:antagonists & inhibitors; D006062:Gonadotropins / Q000037:antagonists & inhibitors*; D007118:Immunoassay; D007986:Luteinizing Hormone / Q000037:antagonists & inhibitors; D008297:Male; D012661:Semen / Q000032:analysis*; D013735:Testicular Hormones / Q000494:pharmacology*; D014659:Vasectomy
chemical_list: D006062:Gonadotropins; D013735:Testicular Hormones; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone