[Tubular nephropathy in chronic polyarthritis].
Disc electrophoresis and N-acetyl-beta-D-glucosaminidase (NAG) of urine are sensitive indicators of renal damage. In 28 from 50 patients with definite rheumatoid arthritis, a tubular proteinuria and a high urinary NAG-excretion and in 10 other patients one of these pathological parameters were detected. A positive correlation with disease activity was noted. Both methods are able to demonstrate a rheumatoid involvement of renal function.
D000118:Acetylglucosaminidase / Q000652:urine; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004008:Diclofenac / Q000627:therapeutic use; D004589:Electrophoresis, Disc; D005260:Female; D006046:Gold / Q000627:therapeutic use; D006801:Humans; D007684:Kidney Tubules; D008297:Male; D008875:Middle Aged; D010396:Penicillamine / Q000627:therapeutic use; D011507:Proteinuria / Q000209:etiology*
D004008:Diclofenac; D006046:Gold; D003520:Cyclophosphamide; D000118:Acetylglucosaminidase; D010396:Penicillamine
Tubuläre Nephropathie bei chronischer Polyarthritis.