title: [Analysis of the effectiveness of treating children with different forms of intellectual deficiency with piriditol].
abstract: The clinical efficacy of piriditol treatment in children with intellectual insufficiency was studied by means of special techniques, determining the velocity of visual information processing (VVIP) and short-time visual memory (SVM), which reflects the functional state of the brain. Piriditol was administered to 50 children aged from 7 to 12 years. The clinical state was characterized as mental retardation, due to mild organic brain lesions or oligophrenia in the form of mild debility. The use of special techniques (VVIP and SVM) for the study of intellectual activity permitted to analyze more differentially the stimulating and sedative effect of piriditol, to detect the new property of the drug, i.e. to remove the processes of fatigue in the brain tissues. A positive effect of the treatment was most marked in children with mental retardation rather than in oligophrenic patients.
mesh_terms: D002648:Child; D003201:Computers; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008570:Memory, Short-Term / Q000187:drug effects*; D011725:Pyridines / Q000627:therapeutic use*; D011746:Pyrithioxin / Q000627:therapeutic use*; D013997:Time Factors; D014796:Visual Perception / Q000187:drug effects*
chemical_list: D011725:Pyridines; D011746:Pyrithioxin
vernacular_title: Analiz éffektivnosti lecheniia piriditolom deteĭ s razlichnymi formami intellektual'noĭ nedostatochnosti.