title: [Effect of preparations on the capacity of thyroxine to suppress compensatory thyroid hypertrophy in rats].
abstract: It has been shown in compensatory hypertrophy of the thyroid gland of male rats weighing 180--240 g that of 18 compounds tested five drugs (cyclic AMP, theophylline, phenformin, tryptophan and disulfiram) reduce an inhibitory effect of thyroxin and are likely to raise the threshold of homeostatic inhibition in the hypothalamohypophyseal and thyroid system.
mesh_terms: D000375:Aging / Q000187:drug effects; D000818:Animals; D006706:Homeostasis / Q000187:drug effects; D006984:Hypertrophy / Q000139:chemically induced; D008297:Male; D051381:Rats; D013268:Stimulation, Chemical; D013961:Thyroid Gland / Q000187:drug effects* / Q000473:pathology; D013965:Thyroidectomy; D013974:Thyroxine / Q000037:antagonists & inhibitors*; D013997:Time Factors
chemical_list: D013974:Thyroxine
vernacular_title: Vliianie nekotorykh preparatov na sposobnost' tiroksina k podavleniiu kompensatornoĭ gipertrofii shchitovidnoĭ zhelezy u krys.