Effect of diffusional lag time on multicompartmental pharmacokinetics for transepidermal infusion.
A simple proof is given to demonstrate that the lag time to reach steady state from transepidermal infusion is the sum of the diffusional and pharmacokinetic lag times.
D004058:Diffusion; D004817:Epidermis; D007263:Infusions, Parenteral; D007700:Kinetics; D008954:Models, Biological; D012869:Skin Absorption