title: Families of manic-depressive patients: effect of treatment.
abstract: The authors studied the families of 12 patients with bipolar manic-depressive illness. They measured family stability using a life events scale for a 2-year period before lithium treatment and for 2 years during lithium treatment. The patients responded well to treatment; they were able to resume normal roles within the family. The life events scores decreased substantially during treatment in comparison with before treatment. The most severe impact of the illness was found in the children: 45% (N = 10) were moderately ill or symptomatic. The authors discuss the effect of manic-depressive illness on the family system as a whole and emphasize the need to combine psychosocial treatment with lithium treatment.
mesh_terms: D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy / Q000628:therapy; D002648:Child; D002653:Child Behavior Disorders / Q000209:etiology; D003376:Counseling; D003674:Defense Mechanisms; D005190:Family; D005196:Family Therapy; D005260:Female; D006760:Hospitalization; D006801:Humans; D007398:Interpersonal Relations; D008016:Life Change Events; D008094:Lithium / Q000627:therapeutic use; D008297:Male; D008393:Marriage; D010287:Parent-Child Relations
chemical_list: D008094:Lithium