Rapid assessment of fetal pulmonary maturity.
The absorbance of amniotic fluid at 653 nm has been measured in 300 specimens and found to have a significant correlation with the L/S ratio. Then 118 patients were further evaluated for neonatal outcome. RDS was absent in 99% of patients with mature absorbance values. This determination has the advantage of rapid performance without specialized equipment or training and represents a significant contribution to the assessment of fetal pulmonary maturity.
D000653:Amniotic Fluid / Q000032:analysis*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000196:embryology* / Q000502:physiology; D010713:Phosphatidylcholines / Q000032:analysis; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D012127:Respiratory Distress Syndrome, Newborn / Q000175:diagnosis; D012306:Risk; D013057:Spectrum Analysis; D013109:Sphingomyelins / Q000032:analysis
D010713:Phosphatidylcholines; D013109:Sphingomyelins