title: Large airway obstruction secondary to endobronchial coccidioidomycosis.
abstract: When clinically apparent, coccidioidomycosis usually presents either as an interstitial pulmonary infiltrate or, later in its course, a parenchymal nodule often with cavitation. The present report concerns a young adult woman whose presentation was one of shortness of breath with wheezing and stridor, secondary to a localized endobronchial coccidiodal granuloma producing nearly complete obstruction of the right mainstem bronchus. Such a presentation has not been reported previously in an adult. The possible association of serious fungal disease with previous jejunoileal bypass surgery is discussed.
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000175:diagnosis / Q000209:etiology*; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D001982:Bronchial Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D001999:Bronchoscopy; D003047:Coccidioidomycosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D006801:Humans; D014056:Tomography, X-Ray
chemical_list: D000666:Amphotericin B