Effect of mianserin on cardiac conduction.
A cardiovascular study of a new antidepressant, mianserin, given at 60 mg a day for a three-week period to 10 ambulant, moderately depressed patients is described. No effects on cardiac conduction were found by means of His bundle electrocardiography. Nine of 10 depressed patients improved while on the medication; mild sedation was the only side effect noted.
D000328:Adult; D003863:Depression / Q000188:drug therapy; D003984:Dibenzazepines / Q000494:pharmacology*; D005260:Female; D006321:Heart / Q000187:drug effects; D006329:Heart Conduction System / Q000187:drug effects*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008803:Mianserin / Q000494:pharmacology*; D008875:Middle Aged
D003984:Dibenzazepines; D008803:Mianserin