Genetics of hyperuricemia in families with gout.
Complex segregation analysis supports the polygenic hypothesis of Hauge and Harvald and Neel et al, according to which hyperuricemia ascertained through gout is rarely due to a major gene, evidence for which is not significant in two studies that were considered to favor a major locus.
D005787:Gene Frequency; D014644:Genetic Variation; D006073:Gout / Q000235:genetics*; D006801:Humans; D008433:Mathematics; D008957:Models, Genetic; D014527:Uric Acid / Q000652:urine*
D014527:Uric Acid