DNA content in human uterine cervical dysplasias.
The DNA content of nuclei extracted from separate biopsies of normal cervical epithelium and from dysplastic sites in the same patient was determined biochemically. Mean percentage increase in the DNA content of dysplasias (mild: 143.3 +/- 14.9; moderate: 225.8 +/- 51.1; and severe: 359.8 +/- 45.8) was found to be statistically significant (F-Test: p less than 0.001) over the normal values in control cervical tissues.
D000293:Adolescent; D000328:Adult; D002584:Cervix Uteri / Q000032:analysis / Q000473:pathology*; D004247:DNA / Q000032:analysis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011230:Precancerous Conditions / Q000378:metabolism*
D004247:DNA