title: [Value of the enzyme tests in the evaluation of the severity of disease and prognosis in acute myocardial infarct].
abstract: The article discusses the results of simultaneous tests for the activity of total lactate dehydrogenase (LDH), its isoenzymes and creatine phosphokinase (CPK) in blood serum of 450 patients with macrofocal myocardial infarction; in 213 of them the disease followed a severe course and in 237 a mild course. The activity of these enzymes was used in this group of patients for judging the immediate and in 190 patients wht late prognosis. The authors' study showed that the maximum indices of the activity of LDH, LDH1 fraction and CPK in blood serum were higher in patients with severe myocardial infarction than in those with a mild course of the disease. The immediate and late prognosis in myocardial infarction was graver in higher activity of serum enzymes.
mesh_terms: D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood*; D005069:Evaluation Studies as Topic; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000201:enzymology / Q000401:mortality; D011379:Prognosis
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase
vernacular_title: Znachenie opredeleniia aktivnosti fermentov v syvorotke krovi v otsenke tiazhesti zabolevaniia i prognoza u bol'nykh ostrym infarktom miokarda.