The use of fluorescein in radical inguinal lymphadenectomy.
Necrosis with slough of skin flaps is a common and distressing complication after radical inguinal node dissection. Conventional methods to predict viability of dermal flaps are notoriously unreliable. Intravenous fluorescein has been shown to be a reliable indicator of the adequacy of blood supply to dermal flaps in experimental models and in radical mastectomies. Fluorescein has been used in 6 separate node dissections for carcinoma of the penis. In all cases fluorescein reliably delineated viable skin flaps and its use can help decrease the morbidity rate in inguinal node dissection.
D002294:Carcinoma, Squamous Cell / Q000628:therapy; D005451:Fluorescein Angiography; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D009336:Necrosis; D010412:Penile Neoplasms / Q000628:therapy; D011183:Postoperative Complications / Q000517:prevention & control; D012867:Skin / Q000098:blood supply; D013524:Surgical Flaps