The acute toxicity of ethanol: dosage and kinetic nomograms.
We are concerned with the frequency of potentially lethal ethanol intoxications (about 1 pint of hard liquor) in teenagers. We present 2 illustrative cases, discuss the acute toxicity of ethanol, and present 2 simple calculating charts for dosage and kinetics. The widespread use and economic impact of ethanol have kept this potent sedative-hypnotic free of the same federal regulations that control the availability of other drugs with a similar potency and margin of safety.
D000079:Acetaldehyde / Q000378:metabolism; D000293:Adolescent; D000435:Alcoholic Intoxication / Q000503:physiopathology*; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000097:blood / Q000378:metabolism; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D008954:Models, Biological
D000431:Ethanol; D000079:Acetaldehyde