title: [Blood hormones in chronic ischemic heart disease and acute myocardial infarct].
abstract: The activity of some blood hormones was determined by radioimmune analysis in 58 patients with chronic ischemic heart disease (CIHD), 60 patients with myocardial infarction (MI) and in 24 practically healthy individuals. Increased activity of pituitary hormones (ACTH and TTH) with simultaneous increase in the blood STH content in the absence of essential changes in the FSH and LH content was established. These shifts in the production of pituitary hormones are evidently due both to disorders in the hypothalamo-hypophyseal area and to changes in the activity of systems coordinated to the pituitary gland in patients with CIHD. In patients with MI the activity of these hormones in blood does not differ from that in the control group. In patients with CIHD, the activity of the thyroid is diminished due to a decrease in its thyroxin-producing ability against the background of high activity of the pituitary thyreotropic function. The discussed shifts in the activity of some hormones in CIND and MI are conducive to the advancement of atherosclerosis and changes in myocardial metabolism.
mesh_terms: D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000097:blood; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003327:Coronary Disease / Q000097:blood*; D012739:Gonadal Steroid Hormones / Q000097:blood; D006728:Hormones / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D010187:Pancreatic Hormones / Q000097:blood; D010907:Pituitary Hormones / Q000097:blood; D012083:Renin / Q000097:blood; D013963:Thyroid Hormones / Q000097:blood; D013997:Time Factors
chemical_list: D000305:Adrenal Cortex Hormones; D012739:Gonadal Steroid Hormones; D006728:Hormones; D010187:Pancreatic Hormones; D010907:Pituitary Hormones; D013963:Thyroid Hormones; D012083:Renin
vernacular_title: Gormony krovi pri khronicheskoĭ ishemicheskoĭ bolezni serdtsa i ostrom infarkte miokarda.