The excretion of trace elements in rat urine after treatment with 2,3-dimercaptopropane sodium sulfonate.
Administration of various doses of the chelating agent 2,3-dimercaptopropane sodium sulfonate (Dimaval, DMPS) leads to a greatly enhanced excretion of Zn and Cu. The excretion of Co, Mn, Ni and Fe remains unchanged. The relevance of these findings to the toxicity of DMPS is discussed.
D000818:Animals; D004112:Dimercaprol / Q000031:analogs & derivatives* / Q000494:pharmacology; D008297:Male; D051381:Rats; D014131:Trace Elements / Q000652:urine*
D014131:Trace Elements; D004112:Dimercaprol