title: Is appendicitis familial?
abstract: A family history of appendicectomy was sought in two groups of children admitted to Llandough Hospital over sixteen months. The study group consisted of 29 children with histologically confirmed acute appendicitis, while the control group consisted of 29 children admitted for reasons unrelated to abdominal pain. A history of appendicectomy was elicited in first-degree relatives--that is, siblings and parents of 20 of the children in the study group and of four of the controls--a statistically significant difference. The results obtained from this study suggest that a familial predisposition to appendicitis exists.
mesh_terms: D000208:Acute Disease; D001062:Appendectomy; D001064:Appendicitis / Q000235:genetics* / Q000601:surgery; D002648:Child; D005260:Female; D006801:Humans; D008297:Male