Treatment of acute phenothiazine reaction.
Dystonic reactions induced by phenothiazines are not uncommon, yet rapid relief of symptoms is still often delayed. We think that a test dose of diphenhydramine should be given for its diagnostic and therapeutic efficacy when phenothiazine-induced dystonic reactions are suspected. Differential diagnostic testing should then proceed. We present three typical cases and discuss the therapy and diagnosis.
D000328:Adult; D002648:Child; D004155:Diphenhydramine / Q000627:therapeutic use; D004421:Dystonia / Q000139:chemically induced* / Q000188:drug therapy; D006801:Humans; D008297:Male; D010640:Phenothiazines / Q000009:adverse effects*
D010640:Phenothiazines; D004155:Diphenhydramine