Hemophilia and the female: considerations for the radiologist.
Hemophilia A and B are commonly considered male diseases because of their X-linked recessive inheritance, but clinical hemophilia is occasionally seen in females. This may represent an extreme example of the Lyon hypothesis in which a heterozygous female has only the one X chromosome bearing the aberrant gene in the active state.
D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000473:pathology; D002348:Carpal Bones; D002648:Child; D005260:Female; D005269:Femur; D005838:Genotype; D006467:Hemophilia A / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008297:Male; D010641:Phenotype; D011859:Radiography; D012729:Sex Chromosome Aberrations; D012737:Sex Factors; D013977:Tibia; D014960:X Chromosome