title: Interferon response to human diploid cell strain rabies vaccines in man.
abstract: Circulating interferon was found in volunteers immunized with 3.0 ml and 1.0 ml doses of human diploid cell strain (HDCS) rabies vaccines. Peak interferon titres were observed 17--25 hours after primary vaccination and the response diminished upon revaccination. The response was dose-related and did not correlate with the antigenic value of the vaccines or with the titre of infections virus in the vaccines before inactivation.
mesh_terms: D002460:Cell Line; D004171:Diploidy; D004306:Dose-Response Relationship, Immunologic; D006801:Humans; D007273:Injections, Intramuscular; D007372:Interferons / Q000097:blood*; D011819:Rabies Vaccines / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D011819:Rabies Vaccines; D007372:Interferons