Effect of growth hormone on lymphocyte respiration and growth rate of children.
Oxygen consumption by circulating lymphocytes of children with isolated growth hormone deficiency was studied before and 6 mo after the start of growth hormone therapy. A plot of percent change in respiration (oxygen consumed per mg protein or microgram DNA) against height gain during the therapy showed a linear association (correlation coefficient 0.667--0.756).
D000293:Adolescent; D001827:Body Height / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D005260:Female; D006130:Growth Disorders / Q000188:drug therapy / Q000378:metabolism; D013006:Growth Hormone / Q000172:deficiency* / Q000627:therapeutic use; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism*; D008297:Male; D010101:Oxygen Consumption / Q000187:drug effects*
D013006:Growth Hormone