title: Effect of modification of the essential catalytic residues in alpha-chymotrypsin on the thermodynamics of substrate analog association.
mesh_terms: D000098:Acetophenones; D000478:Alkylation; D001665:Binding Sites; D002918:Chymotrypsin / Q000378:metabolism; D006639:Histidine; D007700:Kinetics; D011485:Protein Binding; D013379:Substrate Specificity; D013816:Thermodynamics
chemical_list: D000098:Acetophenones; D006639:Histidine; D002918:Chymotrypsin