title: A comparison of the processes of ventricular coarctation and choroid and ependymal fusion in the mouse brain.
abstract: Lateral ventricular coarctation and fusion of the choroid and ependyma was studied in prenatal and postnatal mice. Coarctation of the lateral ventricle was preceded by the presence of a large quantity of extracellular glycogen embedded in an electron-dense, amorphous matrix lying between the ventricular walls. As the site of coarctation is approached the quantity of glycogen and ground substance decreases and eventually the cilia and microvilli of the ependymal cells also disappear and adjacent walls are joined by maculae adherentes. The glycogen may be produced by the choroid plexus. The presence of cilia seems necessary for coarctation to occur. Fusion of the choroid plexus with the ependyma appears to be due simply to entanglement of choroidal microvilli and ependymal cilia without any specialised cell to cell connexions being present.
mesh_terms: D000818:Animals; D002552:Cerebral Ventricles / Q000032:analysis / Q000196:embryology* / Q000648:ultrastructure; D002831:Choroid Plexus / Q000196:embryology* / Q000648:ultrastructure; D002923:Cilia / Q000648:ultrastructure; D004805:Ependyma / Q000196:embryology / Q000648:ultrastructure; D006003:Glycogen / Q000032:analysis; D051379:Mice; D008854:Microscopy, Electron; D008871:Microvilli / Q000648:ultrastructure
chemical_list: D006003:Glycogen