title: Problems associated with the development of a colony of aged mice for experimental purposes.
abstract: Old animals are not commercially available in the U.K. The following problems associated with the supply of aged C57BL mice to an experimental group over a period of 12 years are discussed: the choice of animal, initial assumptions about management, and husbandry and its change with time. Finally, the recurrent problems which remain if valuable animals are to be kept disease-free yet available to experimentalists are listed.
mesh_terms: D000375:Aging; D000818:Animals; D051379:Mice; D008810:Mice, Inbred C57BL; D008954:Models, Biological