title: [Three hypothalamic tumours: clinical, biologic, X-ray and therapeutic study (author's transl)].
abstract: On the basis of 3 cases of hypothalamic tumours (glioma of the hypothalamus or of the stem of the pituitary, glioma of the hypothalamus or of the optic chiasma, pinealoblastoma), the authors emphasise: (1) the existence of a special endocrine "formula" since it often combines anterior pituitary insufficiency, diabetes insipidus and moderate hyperprolactinaemia; (2) the remarkable efficacy, in all 3 cases, of cobalt therapy, tumour regression becoming complete during the 6 to 10 months following the end of radiotherapy; (3) the post-radiotherapeutic endocrine complications, endocrine deficit becoming greater whilst the tumour disappeared; (4) the diagnostic possibilities and above all regular surveillance now made possible by tomodensitometry.
mesh_terms: D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000532:radiotherapy; D002648:Child; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003919:Diabetes Insipidus / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D005910:Glioma / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000532:radiotherapy; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology; D007031:Hypothalamus / Q000000981:diagnostic imaging; D008297:Male; D010871:Pinealoma / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000532:radiotherapy; D010908:Pituitary Hormones, Anterior / Q000172:deficiency; D011388:Prolactin / Q000097:blood; D014057:Tomography, X-Ray Computed
chemical_list: D003037:Cobalt Radioisotopes; D010908:Pituitary Hormones, Anterior; D011388:Prolactin
vernacular_title: Etude clinique, biologique, radiologique et thérapeutique de 3 tumeurs hypothalamiques. Gliomes et pinéalome.