[Kinetics of morphological and histochemical changes in the spleen under conditions of ovarian neoplasms developing in same and of administration of anticollagen serum].
Experimentally, on the Biskind model it was shown that the development of ovarian tumors transplanted into the spleen is proceded by a progressive reduction in the amount of active splenic cell elements, containing serotonin and hydrolytic enzymes, and by the increased changes in the structure and chemical composition of non-cellular elements of its connective tissue framework with catecholamines accumulated in the latter and the remaining cells. The injection of anticollagen serum (ACS) would increase the terms of tumors arising with the resultant predominance of their benign forms.
D000818:Animals; D000906:Antibodies / Q000008:administration & dosage*; D003094:Collagen / Q000276:immunology*; D005260:Female; D006867:Hydrolases / Q000378:metabolism; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000473:pathology; D010051:Ovarian Neoplasms / Q000473:pathology*; D051381:Rats; D013154:Spleen / Q000187:drug effects / Q000201:enzymology / Q000473:pathology
D000906:Antibodies; D003094:Collagen; D006867:Hydrolases
Dinamika morfologicheskikh i gistokhimicheskikh izmeneniĭ v selezenke pri razvitii v neĭ opukholeĭ iaichnika i pri primenenii antikollagenovoĭ syvorotki.