Preparation of factor VIII concentrates by cryoprecipitate sedimentation.
A new method for factor VIII concentrate preparation is proposed. The method is the collection of cryoprecipitate after sedimentation at 4 C in a jacketed glass vessel. The final product is standardized (4.0 +/- 0.3 factor VIII units per ml) and can be infused in hemophilic patients regardless of their ABO blood type. Factor VIII recovery (52.2 +/- 6.4%) is comparable to other processes.
D001803:Blood Transfusion; D011232:Chemical Precipitation; D003080:Cold Temperature; D005169:Factor VIII / Q000302:isolation & purification*; D006801:Humans; D008722:Methods
D005169:Factor VIII