Inhibition of protein synthesis in vitro by a lectin from Momordica charantia and by other haemagglutinins.
Protein synthesis by a rabbit reticulocyte lysate is inhibited by the haemagglutinating lectins from Momordica charantia and Crotalaria juncea seeds and from the roe of Rutilus rutilus, and by a commercial preparation of the mitogenic lectin from Phytolacca americana. The haemagglutinins from the seeds of Ricinus communis and of Vicia cracca acquired inhibitory activity after their reduction with 2-mercaptoethanol.
D002474:Cell-Free System; D006388:Hemagglutinins / Q000494:pharmacology; D066298:In Vitro Techniques; D037102:Lectins / Q000494:pharmacology*; D008623:Mercaptoethanol; D037121:Plant Lectins; D014176:Protein Biosynthesis; D012639:Seeds / Q000032:analysis
D006388:Hemagglutinins; D037102:Lectins; D037121:Plant Lectins; D008623:Mercaptoethanol