[Enzymatic exonuclease poly(A) degradation activity in liver nucleus and cytoplasm of rats].
Poly(A) degrading activities are detectable in nuclear, nucleoplasmic, cytoplasmic extracts and chromatin preparations from rat liver. More than 75% of the activity has been found within the nucleus; most of the nuclear activity is chromatin bound. Poly(A) degradation appears to occur largely via exonucleolitic cleavage.
D000249:Adenosine Monophosphate / Q000378:metabolism; D000818:Animals; D002467:Cell Nucleus / Q000201:enzymology*; D002843:Chromatin / Q000201:enzymology; D003593:Cytoplasm / Q000201:enzymology*; D004720:Endonucleases / Q000378:metabolism; D005092:Exonucleases / Q000378:metabolism*; D008099:Liver / Q000166:cytology / Q000201:enzymology*; D008297:Male; D011061:Poly A; D051381:Rats; D012260:Ribonucleases / Q000378:metabolism*
D002843:Chromatin; D011061:Poly A; D000249:Adenosine Monophosphate; D004720:Endonucleases; D005092:Exonucleases; D012260:Ribonucleases
Attivita' enzimatiche esonucleasiche degradanti il poli(A) presenti nel nucleo e nel citoplasma di fegato di ratto.