title: Endothelial lesions after temporary clipping. A comparative study.
abstract: The effect of temporary clipping on the arterial endothelium of rats was examined with scanning electron microscopy. The opening pressure of four Heifetz clips was modified by changing the springs. Four different clip forces (20, 35, 45, and 65 gm), four periods of clipping (10, 30, 60, and 180 minutes), and three vessel diameters (smaller than 1 mm, 1.1 to 1.3 mm, and 1.4 to 2 mm) were compared. Different grades of endothelial damage were observed. On gross examination the damage involved a detachment of endothelium and the adherence of platelets to the subendothelial tissue. The duration of clipping seemed to be of more importance than the clip force, whereas the vessel diameter had no recognizable influence.
mesh_terms: D000818:Animals; D001158:Arteries / Q000293:injuries*; D004848:Epithelium; D005260:Female; D008297:Male; D008866:Microsurgery; D051381:Rats; D013523:Surgical Equipment; D013927:Thrombosis / Q000209:etiology*; D014656:Vascular Surgical Procedures / Q000009:adverse effects*