Cutis mamorata telangiectatica congenita in two sisters.
Cutis marmorata telangiectatica congenita was observed in two adult sisters. The condition appeared at birth and did not change much with age. In one sister the condition was accompanied by hypertension, acrocyanosis and ulceration of the big toe. On the basis of a comparison of the symptoms in patients and their relatives, the authors assume that Van Lohuizen syndrome is a dominantly inherited genetic disorder with low penetrance and great intrafamilial variability.
D000328:Adult; D005260:Female; D006801:Humans; D010375:Pedigree; D012871:Skin Diseases / Q000150:complications / Q000151:congenital* / Q000235:genetics; D013577:Syndrome; D013684:Telangiectasis / Q000150:complications / Q000151:congenital* / Q000235:genetics