Estrogen biosynthesis and its inhibition--a review.
A short review is given about extragonadal sources of estrogens via androgen aromatization; the possible importance of this aromatization; the mechanism of aromatization, the inhibition of androgen aromatization by steroidal compounds; the importance and possible usefulness of such an inhibition.
D000328:Adult; D000728:Androgens / Q000378:metabolism* / Q000494:pharmacology; D000735:Androstenedione / Q000378:metabolism; D047072:Aromatase Inhibitors; D004967:Estrogens / Q000096:biosynthesis* / Q000494:pharmacology; D004970:Estrone / Q000096:biosynthesis; D005260:Female; D006801:Humans; D008297:Male; D010920:Placenta / Q000201:enzymology; D013329:Structure-Activity Relationship
D000728:Androgens; D047072:Aromatase Inhibitors; D004967:Estrogens; D004970:Estrone; D000735:Androstenedione