title: Use of dextran 150 as a macromolecular agent to improve granulocyte yields on the intermittent flow blood cell separator (Haemonetics Model 30).
abstract: Leukaphereses were performed on the intermittent flow cell separator (Haemonentics Model 30) using citrated dextran 150 as a macromolecular agent to improve separation of granulocytes. A mean of 1.77 X 10(10) granulocytes and 7.73 X 10(11) platelets were obtained without steroid stimulation and 2.65 X 10(10) granulocytes and 8.91 X 10(11) platelets were obtained with steroid stimulation of donors. There were no significant adverse reactions to dextran.
mesh_terms: D002469:Cell Separation / Q000379:methods*; D003911:Dextrans / Q000494:pharmacology*; D006098:Granulocytes; D006801:Humans; D007937:Leukapheresis
chemical_list: D003911:Dextrans