Acute renal failure in marathon runners.
The Comrades Marathon is a gruelling test of man's stamina and only trained athletes participate. It is surprising that of over 2,000 contestants each year on a 90-km (56.25-mile) course, severe cardiac and renal damage does not occur more often. We are able, however, to report 10 cases over 9 years when renal damage did occur. 3 cases required haemodialysis; 1 had peritoneal dialysis; 2 patients had renal biopsies. Possible idiosyncratic factors are discussed as is the pathogenesis of acute tubular necrosis.
D058186:Acute Kidney Injury / Q000209:etiology* / Q000378:metabolism; D000328:Adult; D006801:Humans; D008297:Male; D009212:Myoglobinuria / Q000150:complications; D012420:Running