The use of bone core biopsies for cytogenetic analysis.
Cultures of bone core specimens have proved satisfactory for cytogenetic analysis in patients from whom it was impossible to obtain a bone marrow aspirate, or in whose peripheral blood dividing myeloid cells were absent or insufficient in number. The quality of the metaphase chromosome is adequate for banding studies.
D000328:Adult; D001706:Biopsy; D001842:Bone and Bones / Q000473:pathology*; D002869:Chromosome Aberrations / Q000473:pathology; D025063:Chromosome Disorders; D002877:Chromosomes, Human / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged