[Role of acid anion in formation of low-soluble aggregates of immunoglobulin G characteristic of malignant growth].
The acid medium favour the formation of low-soluble aggregates in the cancer patient blood serum. An anion of the acid utilized for creation of the aggregate-forming medium is involved into composition of the agregates. The elementary quantitative analysis of such aggregates showed that the amount of the incorporating anion is in inverse dependence on its affinity for proteins. The anion is established to participate at the stage of the low-soluble complex formation. A schematic model is suggested for low-soluble aggregates formed in the cancer patient blood cerum under the effect of the acid medium.
D000838:Anions; D006801:Humans; D007074:Immunoglobulin G; D046911:Macromolecular Substances; D009369:Neoplasms / Q000276:immunology*; D012995:Solubility
D000838:Anions; D007074:Immunoglobulin G; D046911:Macromolecular Substances
Rol' aniona kisloty v obrazovanii malorastvorimykh agregatov immunoglobulina G, kharadternogo dlia zlokachestvennogo rosta.