title: [Treatment of alopecia areata with dinitrochlorobenzol (DNCB)].
abstract: Twenty-two patients with severe forms of alopecia areata were treated about 4--16 months with dinitrochlorobenzene (DNCB) dissolved in acetone. According to the patients' reactivity to DNCB the chemical was applied to the scalp in various concentration once a week. In 14 patients we observed the therapeutic effect of DNCB is unknown. Possibly it might be due to a change in the local immunoregulation. At the present time this treatment cannot be recommended for general use.
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000506:Alopecia Areata / Q000188:drug therapy*; D002648:Child; D003877:Dermatitis, Contact; D004137:Dinitrochlorobenzene / Q000008:administration & dosage / Q000627:therapeutic use*; D005138:Eyebrows; D005140:Eyelashes; D005260:Female; D006801:Humans; D007114:Immunization; D008297:Male; D009578:Nitrobenzenes / Q000627:therapeutic use*
chemical_list: D004137:Dinitrochlorobenzene; D009578:Nitrobenzenes
vernacular_title: Zur Behandlung der Alopecia areata mit Dinitrochlorbenzol (DNCB).