A rapid, sensitive method for quantifying enflurane in whole blood.
Thermal conductively detection (TCD) in conjunction with gas-liquid chromatography was employed for the analysis of enflurane in n-heptane extracts of whole blood. Enflurane was estimated to be 98 per cent extracted from whole blood by n-heptane. Analysis of enflurane standards ranging in concentration from 4.1 to 813 muM demonstrated linearity, with a correlation coefficient of 0.9999. As little as 8 muM enflurane may be detected in whole blood. TCD gas-liquid chromatography is a rapid and sensitive method for quantifying enflurane in whole blood.
D002849:Chromatography, Gas; D004737:Enflurane / Q000097:blood*; D006536:Heptanes / Q000494:pharmacology; D006801:Humans; D013814:Thermal Conductivity; D013997:Time Factors
D006536:Heptanes; D004737:Enflurane