Estradiol and testosterone levels in the peripheral and ovarian circulations in patients with endometrial cancer.
Estradiol and testosterone levels in the peripheral and ovarian circulation of patients with endometrial cancer and of postmenopausal women were studied. These levels proved to be the same in the two groups. The ovaries of neither group secreted estradiol. The testosterone level in the ovarian circulation of all examined women was four times higher than that in the peripheral circulation, thus indicating the ovarian origin of testosterone.
D000368:Aged; D004958:Estradiol / Q000097:blood* / Q000378:metabolism; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D010053:Ovary / Q000098:blood supply* / Q000378:metabolism; D013739:Testosterone / Q000097:blood* / Q000378:metabolism; D014594:Uterine Neoplasms / Q000097:blood* / Q000378:metabolism
D013739:Testosterone; D004958:Estradiol