Uterine oestrogen-receptor binding to oligo(dT)-cellulose. An inhibitor from hypothalamic cytosol.
The binding of rat uterine cytosol oestrogen receptor in vitro to oligo(dT)-cellulose is mediated by an activating factor in the cytosol [Thrower, Hall, Lim & Davison (1976) Biochem. J. 160, 271-280]. A potent inhibitor of this binding is present in hypothalamic cytosol. This inhibitor may have a role in vivo in regulating receptor translocation in the hypothalamus.
D000818:Animals; D002457:Cell Extracts / Q000494:pharmacology*; D002482:Cellulose / Q000031:analogs & derivatives* / Q000378:metabolism; D003600:Cytosol; D003864:Depression, Chemical; D004958:Estradiol; D005260:Female; D007031:Hypothalamus / Q000166:cytology*; D066298:In Vitro Techniques; D009838:Oligodeoxyribonucleotides / Q000378:metabolism; D051381:Rats; D011960:Receptors, Estrogen / Q000187:drug effects* / Q000378:metabolism; D014020:Tissue Extracts / Q000494:pharmacology*; D014599:Uterus / Q000378:metabolism*
D002457:Cell Extracts; D009838:Oligodeoxyribonucleotides; D011960:Receptors, Estrogen; D014020:Tissue Extracts; C021722:oligo(dT)-cellulose; D004958:Estradiol; D002482:Cellulose