[Effect of hepatic adhesion factor, contactin, on the mechanical properties of ultrastructural elements of hepatocyte contact].
Injection of isotonic fluid under heightened pressure 20--30 mm of Hg into the bed of the liver reveals inhomogeneity of the mechanical properties of the simple junction of heptacytes: the zone where the divergence of the contact surfaces is observed is interrupted by highly adhesive regions (HAR) where the normal distance between the membranes is preserved. The adhesive factor acts as an organizer of the inhomogeneity of the simple junction: when it is introduced in vivo, new HAR appear in the simple junction. On account of contact-tropic activity of adhesive factor we termed it--contactin.
D000818:Animals; D002448:Cell Adhesion; D007365:Intercellular Junctions / Q000648:ultrastructure; D008099:Liver / Q000032:analysis* / Q000166:cytology / Q000648:ultrastructure; D008297:Male; D051379:Mice; D008854:Microscopy, Electron; D011506:Proteins / Q000032:analysis / Q000494:pharmacology*
D011506:Proteins
Vliianie adgezionnogo faktora pecheni--kontaktina na mekhanicheskie svoĭstva ul'trastrukturnykh élementov kontakta gepatotsitov.