[Karyotypic variability of a tumor cell population in the process of prolonged growth in the body].
An ascite variant of spontaneous mammary gland tumor of C3H/Sn mice was transplanted subcutaneously into syngenic mice. During the tumor growth (150 days) some alterations occur in the genetical structure of the tumor population: a change in the stem line, the increase and a further decrease of nearoctaploid cells.
D000818:Animals; D005260:Female; D014644:Genetic Variation; D007621:Karyotyping; D008325:Mammary Neoplasms, Experimental / Q000235:genetics*; D051379:Mice; D008809:Mice, Inbred C3H; D011003:Ploidies; D013997:Time Factors
Izuchenie kariotipicheskoĭ izmenchivosti populiatsii opukholevykh kletok v protsesse dlitel'nogo rosta v organisma.