title: Possible mutagenic activity of saccharin.
abstract: A mutagenic effect of saccharin in Chinese hamsters, using the in vivo SCE test, was observed when massive overdoses were administered; cyclamate was not mutagenic.
mesh_terms: D000818:Animals; D002869:Chromosome Aberrations; D006224:Cricetinae; D003412:Cricetulus; D003494:Cyclamates / Q000494:pharmacology; D009153:Mutagens; D012439:Saccharin / Q000494:pharmacology*
chemical_list: D003494:Cyclamates; D009153:Mutagens; D012439:Saccharin