title: Ultrastructure of neurofibrillary tangles in progressive supranuclear palsy.
abstract: The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy. Straight tubules and twisted tubules were observed in both the cortical and subcortical neurofibrillary tangles. Most tubules appeared separately in each neuron but a few straight tubules were mixed with the twisted tubules in the cortical tangles. The implication and possible significance of this findings are discussed.
mesh_terms: D000368:Aged; D001344:Autopsy; D001927:Brain Diseases / Q000473:pathology*; D006624:Hippocampus / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009454:Neurofibrils / Q000648:ultrastructure*; D011149:Pons / Q000648:ultrastructure; D013378:Substantia Nigra / Q000648:ultrastructure