Biliary excretion of erythromycin after parenteral administration.
1 The biliary excretion of erythromycin has been studied following parenteral administration in 23 patients. 2 Mean bile levels of the drug were approximately ten times higher than corresponding serum concentrations 1 h after i.v. (erythromycin lactobionate) and i.m. (erythromycin ethylsuccinate) injection. 3 Thus, unlike many antimicrobial agents, these compounds are well concentrated in the bile.
D001646:Bile / Q000378:metabolism*; D004917:Erythromycin / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D006801:Humans; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D013997:Time Factors
D004917:Erythromycin