Changes in CDP-diglyceride:inositol transferase activity during rabbit lung development.
During fetal and neonatal development the specific activity of the enzyme, CDP-diglyceride:inositol transferase in rabbit lung tissue increased 8- to 9-fold from day 17 of gestation to adulthood. This developmental increase in enzyme activity was not specific for lung tissue since a similar increase was also observed in liver tissue. The properties of CDP-diglyceride:inositol transferase in microsomes prepared from either fetal or adult rabbit lung tissue appeared to be the same. The increase in CDP-diglyceride:inositol transferase activity in rabbit lung tissue during development appeared to be reflective of synthesis of new enzyme rather than activation of pre-existing enzyme.
D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism; D003567:Cytidine Diphosphate Diglycerides; D005333:Fetus / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008168:Lung / Q000201:enzymology / Q000254:growth & development; D010770:Phosphotransferases / Q000378:metabolism*; D011817:Rabbits
D003567:Cytidine Diphosphate Diglycerides; D010770:Phosphotransferases