IgG subclasses, barrier function for albumin and production of immunoglobulin G in the central nervous system.
Cerebrospinal fluids from patients with neurological diseases have been studied. It appeared that the detectability of immunoglobulin G subclasses 1, 2, 3, 4, and the occurrence of oligoclonal bands in the IgG region increased with increasing concentration of IgG in the spinal fluid. No specific pattern emerged in the different disease groups. Formula: see text.
D000418:Albumins / Q000134:cerebrospinal fluid*; D001812:Blood-Brain Barrier; D001921:Brain / Q000378:metabolism; D002493:Central Nervous System Diseases / Q000134:cerebrospinal fluid / Q000276:immunology; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis / Q000378:metabolism; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis / Q000134:cerebrospinal fluid*; D009422:Nervous System Diseases / Q000134:cerebrospinal fluid* / Q000276:immunology; D012016:Reference Values
D000418:Albumins; D002556:Cerebrospinal Fluid Proteins; D007074:Immunoglobulin G