[The blood-flow in hands with Dupuytren's contracture and Raynaud disease: functional and morphological studies (author's transl)].
Concerning the question whether a correlation between the vasospasm and morphological changes in the neuro-myo-arterial glomerular (Hoyer-Grosser-Organ) exists also in Dupuytren disease, a series of 18 patients with Dupuytren and 5 patients with Raynaud disease were studied by finger venous occlusion plethysmography and finger tip biopsies. No typical histological changes were found in Dupuytren's Contracture, particularly none in the 13 cases (70%) which had a latent vasospasm and none in the 5 cases (30%) which had a normal plethysmogram, whereas in all the patients with Raynaud disease the typical morphological changes of wall, lumen and morphometric counts of the "Suquet-Hoyer" canals were found in correspondance to the abnormal plethysmogram. According to these results the vasospasm of Dupytren and Raynaud disease seems to be pathogenetically different.
D001775:Blood Circulation; D004387:Dupuytren Contracture / Q000503:physiopathology*; D005385:Fingers / Q000473:pathology; D006225:Hand / Q000503:physiopathology*; D006801:Humans; D010992:Plethysmography, Impedance; D011928:Raynaud Disease / Q000503:physiopathology*; D014661:Vasoconstriction
Funktionelle und morphologische vergleichende Untersuchungen der Durchblutung von Händen mit Dupuytrenscher Kontraktur und Raynaud-Syndrom. Fingervenenverschlussplethysmographie -- Fingerbeerenbiopsie.