[Relationship between incurrent flow, calcium ion concentration and membrane potential].
A dependence of the inward current across the cell membrane giant neurones at garden snail was investigated under voltage champ. It has been concluded that there are two components of the inward current: a calcium-dependent and I0. The latter current probably was carried by sodium ions. The inward Ca current (ICa) is then given as a function [Ca]2+ by: formula (see text) : KCa is a dissociation constant of the sites in outer part channel independent of membrane voltage. The experimental data are interpreted by two barrier membrane model bases of absolute reaction rate Eyring's theory.
D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D002463:Cell Membrane Permeability; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D007473:Ion Channels / Q000502:physiology; D008564:Membrane Potentials; D008954:Models, Biological; D009474:Neurons / Q000187:drug effects*; D012908:Snails
D007473:Ion Channels; D002118:Calcium
Zavisimost' vkhodiashchego toka ot kontsentratsii ionov kal'tsiia i membrannogo potentsiala.