Metabolic acidosis and coma due to an overdose of nalidixic acid.
A case of severe metabolic acidosis and coma after taking 28 g of nalidixic acid is described. After administration of 600 mEq of sodium bicarbonate the patient developed a respiratory alkalosis with secondary tetany. She recovered her state of consciousness nine hours later and the acid-base disturbance resolved after sixty hours.
D000138:Acidosis / Q000139:chemically induced*; D000328:Adult; D003128:Coma / Q000139:chemically induced*; D005260:Female; D006801:Humans; D009268:Nalidixic Acid / Q000506:poisoning*; D013406:Suicide, Attempted
D009268:Nalidixic Acid