title: [Experimental study on canine gastric motility following selective proximal vagotomy (author's transl)].
abstract: Electromyographical studies were made on the gastric motility of dogs following selective vagotomy (SV) and selective proximal vagotomy (SPV) as the subsequent studies on the changes after truncal vagotomy (TV) after which gastric motility is fairly disturbed, and the influence of pyloroplasty additionally performed to SPV. Gastric discharge frequency was suppressed by SV similar to that by TV. Dysrhythmia of motility occurred after gastric vogotomy. Restoration to the normal was the fastest after SPV. Changes in the discharge frequency after SPV did not differ much from those in the normal stomach and other types of vagotomy. With SPV, the decrease in the propagation velocity of basic electrical rhythms (BER) was mild, and a pattern similar to the control was shown compared with TV and SV. The antiperistaltic discharge was observed even with SPV, but the frequency was low compared with TV and SV. The frequency of peristaltic discharge was the highest when pyloroplasty was performed in addition to SPV. The responses to vagostigmine, insulin tetragastrin in SPV were similar to those in the normal stomach. During the gastric emptying time, there was neither difference before and after SPV, nor any significant difference due to the presence or absence of pyloroplasty. The above data show that SPV is advantageous for retaining the function of gastric peristalsis, also for gastric secretion, but the addition of pyloroplasty will not be advantageous for the elimination of gastric content.
mesh_terms: D000200:Action Potentials; D000818:Animals; D004285:Dogs; D004576:Electromyography; D005746:Gastric Emptying; D005753:Gastric Mucosa / Q000378:metabolism; D005769:Gastrointestinal Motility / Q000187:drug effects; D007328:Insulin / Q000494:pharmacology; D009388:Neostigmine / Q000494:pharmacology; D011708:Pylorus / Q000294:innervation / Q000601:surgery; D013270:Stomach / Q000187:drug effects / Q000502:physiology*; D013758:Tetragastrin / Q000494:pharmacology; D014628:Vagotomy
chemical_list: D007328:Insulin; D013758:Tetragastrin; D009388:Neostigmine