title: [Advantages and disadvantages of insulin therapy in elderly diabetics with asymptomatic hyperglycemia].
abstract: 15 elderly diabetic patients with fasting blood glucose levels above 160 mg/100 ml, without hyperglycemic symptoms and previously treated with oral antidiabetic agents, were put on insulin. The change of treatment regimen was made in the outpatient department. Frequent clinical and laboratory controls were performed and the patients were given full instructions for injection technique and diet. On the insulin regimen a prompt and lasting improvement was observed in the metabolic parameters (blood glucose levels both fasting and after food intake, Hb A1c, serum insulin, glucagon and serum lipid concentrations). The so-called "asymptomatic" patients noticed a marked improvement in their general status and performance. Three months after insulin therapy was started 13 of our 15 patients preferred the insulin treatment to oral agents. However, weight gain and a tendency to hypoglycemia were noticed in less disciplined patients. In addition, considerable time was spent on instruction of the patients. Bearing these factors in mind, insulin therapy in elderly diabetics with so-called "sysmptomatic hyperglycemia" can be regarded as worthwhile.
mesh_terms: D000368:Aged; D001835:Body Weight; D003920:Diabetes Mellitus / Q000628:therapy*; D005934:Glucagon / Q000097:blood; D006454:Hemoglobins; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology; D007328:Insulin / Q000097:blood / Q000627:therapeutic use; D008055:Lipids / Q000097:blood; D008875:Middle Aged
chemical_list: D006454:Hemoglobins; D007328:Insulin; D008055:Lipids; D005934:Glucagon
vernacular_title: Vor- und Nachteile der Insulintherapie bei älteren Diabetikern mit Asymptomatischer Hyperglykämie.