UV-induced DNA repair in hairy cell leukaemia patients.
We analysed by liquid scintillation counting and by autoradiography the DNA repair synthesis induced by UV irradiation in mononucleated cells from peripheral blood of 'hairy cell leukaemia' patients. In 9 out of 12 patients the repair activity values obtained in repeated assays were found to be significantly lower than those of healthy donors.
D000328:Adult; D004260:DNA Repair / Q000528:radiation effects*; D004273:DNA, Neoplasm / Q000097:blood*; D005260:Female; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000097:blood*; D007962:Leukocytes / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014466:Ultraviolet Rays
D004273:DNA, Neoplasm