A new pathway of metabolism of chloramphenicol which influences the interpretation of its irreversible binding to protein in vivo.
D000818:Animals; D001798:Blood Proteins / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D002701:Chloramphenicol / Q000378:metabolism*; D005998:Glycine; D006868:Hydrolysis; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology; D011485:Protein Binding; D051381:Rats; D012694:Serine; D014018:Tissue Distribution
D001798:Blood Proteins; D012694:Serine; D002701:Chloramphenicol; D005998:Glycine; D010634:Phenobarbital