[Problems encountered during intensive routine scale performace of paper T4 and TSH radioimmunoassays (author's transl)].
High sensitivity attained in radioimmunoassays explains the important role played by specialized laboratories as screening partners for early neonatal hypothyroidism detection. In this paper, the author tries to point out optimal technical conditions to be followed while performing at routine scale T4 and TSH paper immunoassays choice of filter paper, blood collection and storage, assay, quality control, assay mecanization, computer calculation of results).
D001322:Autoanalysis; D003409:Congenital Hypothyroidism; D006801:Humans; D007231:Infant, Newborn; D008403:Mass Screening / Q000458:organization & administration; D011786:Quality Control; D011863:Radioimmunoassay / Q000379:methods; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood*
D013972:Thyrotropin; D013974:Thyroxine
Etude critique des problèmes associés à la pratique en grande série des dosages radioimmunologiques de T4 et de TSH sur papier.