title: [Persistence of the vaccinia virus and interferon production in the organs of vaccinated white mice].
abstract: Experiments in white mice vaccinated intradermally with live smallpox vaccine demonstrated penetration and long-term persistence of vaccinia virus in the spleen, lymph nodes, lungs and brain. In the same organs interferon was detected. After a certain period of time interferon was found in higher titers and for longer periods than in the blood of the animals which indicates its production directly in these organs.
mesh_terms: D000818:Animals; D001769:Blood / Q000382:microbiology; D001921:Brain / Q000382:microbiology; D007372:Interferons / Q000096:biosynthesis*; D008168:Lung / Q000382:microbiology; D008198:Lymph Nodes / Q000382:microbiology; D051379:Mice; D013154:Spleen / Q000382:microbiology; D013997:Time Factors; D014611:Vaccination; D014616:Vaccinia virus / Q000302:isolation & purification*
chemical_list: D007372:Interferons
vernacular_title: O persistentsii virusa ospovaktsiny i produktsii interferona v organakh vaktsinirovannykh belykh mysheĭ.