Production of interferon in human diploid cell cultures. II. Effect of various factors on interferon production in human diploid cell cultures.
Interferon was induced in primary human embryonic fibroblast cultures, using the Newcastle disease virus and synthetic polynucleotide poly I : poly C. Kinetics of interferon production were studied in this system, and optimal doses of some chemical factors which enhance interferon production were determined.
D002478:Cells, Cultured; D004171:Diploidy; D005347:Fibroblasts; D006801:Humans; D007372:Interferons / Q000096:biosynthesis*; D007700:Kinetics; D009522:Newcastle disease virus / Q000276:immunology*; D011070:Poly I-C / Q000494:pharmacology
D007372:Interferons; D011070:Poly I-C