Effect of halothane on isometric contractile properties of muscle from stress-susceptible and stress-resistant pigs.
The effect of clinical concentrations of halothane on the isometric contractile properties of muscle in stress-susceptible and stress-resistant pigs was studied. Exposure to halothane initially increased the percentage of peak twitch tension in the muscle of stress-susceptible pigs whereas the tension gradually decreased in the stress-resistant group of pigs. Halothane may act as a potentiator of muscle contraction in stress-susceptible animals, but this effect is transitory.
D000818:Animals; D006221:Halothane / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects*; D013312:Stress, Physiological / Q000235:genetics / Q000503:physiopathology / Q000662:veterinary*; D013552:Swine / Q000502:physiology*; D013553:Swine Diseases / Q000235:genetics* / Q000503:physiopathology
D006221:Halothane