[Activity of enzymes of nucleic acid metabolism in rat liver nuclei under induction of RNA synthesis by electric stimulation of hypothalamus].
Electrostimulation of hypothalamus results in an increase of RNA synthesis of the AU-type in liver cells of intact and adrenalectomized rats. No such effect is observed in the animals with denervated liver. An increase in RNA synthesis is accompanied by an increase in the activities of RNA-polymerases II and III and histone hydrolase and a decrease in the activities of RNAse and DNAse. The mechanisms of the effect of the nervous system on the activities of the nucleic acid metabolism enzymes are discussed.
D000818:Animals; D002467:Cell Nucleus / Q000201:enzymology*; D003851:Deoxyribonucleases / Q000378:metabolism; D004558:Electric Stimulation; D007031:Hypothalamus / Q000502:physiology*; D008099:Liver / Q000201:enzymology*; D008297:Male; D012313:RNA / Q000096:biosynthesis*; D012319:RNA Polymerase II / Q000378:metabolism; D012320:RNA Polymerase III / Q000378:metabolism; D051381:Rats; D012260:Ribonucleases / Q000378:metabolism; D014158:Transcription, Genetic
D012313:RNA; D012319:RNA Polymerase II; D012320:RNA Polymerase III; D003851:Deoxyribonucleases; D012260:Ribonucleases
Aktivnost' fermentov obmena nukleinovykh kislot v iadrakh pecheni krys pri induktsii sinteza RNK elektrostimuliatsieĭ gipotalamusa.