Systemic absorption of topically applied chloramphenicol eyedrops.
Five children under the age of 9 years had topical chloramphenicol drops administered 2-hourly to each eye for 5 to 7 days. Systemic absorption was not detected by 2 sensitive assays for the drug. The hazards of topical chloramphenicol and reports in the current literature are discussed.
D000042:Absorption; D002648:Child; D002675:Child, Preschool; D002701:Chloramphenicol / Q000008:administration & dosage / Q000378:metabolism* / Q000652:urine; D004334:Drug Administration Schedule; D006801:Humans; D009883:Ophthalmic Solutions
D009883:Ophthalmic Solutions; D002701:Chloramphenicol