EEG sleep patterns in Parkinsonian patients treated with bromocryptine and L-dopa: a comparative study.
The nocturnal sleep patterns of six Parkinsonian patients treated with Bromocryptine (2-Br-L-ergocryptine CB-154), a dopamine-like agonist, were compared with those of the same patients under L-DOPA treatment. No significant differences were found between the two groups. It is suggested that Bromocryptine, acting on dopamine receptors in the sleep regulating systems at the reticular level in the midbrain has the same effect on sleep patterns of Parkinsonian patients as L-DOPA.
D000368:Aged; D001971:Bromocriptine / Q000627:therapeutic use*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy / Q000503:physiopathology*; D011954:Receptors, Dopamine / Q000187:drug effects; D012154:Reticular Formation; D012890:Sleep / Q000187:drug effects*
D011954:Receptors, Dopamine; D001971:Bromocriptine; D007980:Levodopa