89Strontium therapy of bone metastases of carcinoma of the prostatic gland.
Following a firm diagnostic and therapeutic schedule for patients with prostatic carcinoma. 89Strontium therapy was introduced for multiple metastases. Positive skeletal scintigraphy with 99mTc-EHDP induced check for affinity to Sr using 85Sr scintigraphy. Of 80 patients, multiple metastases were found in 26. Therapy with 1 mCi of 89Sr-chloride was started in 20 cases. In 8 patients, relief from severe pain appeared shortly afterward, and a further 8 it was possible to prevent the development of pain. Moderate success in 3 cases and a failure to provide relief in 1 were observed.
D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D004164:Diphosphonates; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D010148:Intractable Pain / Q000517:prevention & control / Q000532:radiotherapy; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011877:Radionuclide Imaging; D011879:Radiotherapy Dosage; D013326:Strontium Radioisotopes / Q000627:therapeutic use*; D013667:Technetium
D004164:Diphosphonates; D013326:Strontium Radioisotopes; D013667:Technetium