The effect of lidocaine on the secretion induced by cholera toxin in the cat small intestine.
The intraluminal administration of lidocaine, a local anaesthetic agent, inhibits the net loss of fluid into the intestinal lumen produced by cholera toxin in the cat. It is suggested that the activation of a nervous reflex is involved in the pathogenesis of cholera.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D002772:Cholera Toxin / Q000494:pharmacology*; D007421:Intestine, Small / Q000098:blood supply / Q000187:drug effects / Q000378:metabolism*; D008012:Lidocaine / Q000494:pharmacology*; D012039:Regional Blood Flow / Q000187:drug effects
D002772:Cholera Toxin; D008012:Lidocaine