title: [Coumarin necrosis (author's transl)].
abstract: 2 cases of hermorrhagic skin infarctions of breast and thigh after anticoagulation with coumarin are reported. The mechanism of coumarin necrosis remains unknown. Treatment of lesions is necrotomy. A skin graft may be needed to cover the defect.
mesh_terms: D000368:Aged; D001940:Breast; D003374:Coumarins / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D009336:Necrosis; D011655:Pulmonary Embolism / Q000188:drug therapy; D012871:Skin Diseases / Q000139:chemically induced* / Q000601:surgery; D013848:Thigh
chemical_list: D003374:Coumarins
vernacular_title: Cumarin-Nekrose der Haut.