Porphyria and the dangerous life-threatening drugs.
The dangerous life-threatening drugs have been identified in 153 acute attacks in 138 porphyric patients by establishing a consistent temporal relationship between the administration of a specific drug and the development of an acute attack. The drugs so identified have been supplemented by a number of others found to be porphyrogenic by testing with a recently devised rat model. Lists of the dangerous and the safe drugs have been compiled.
D001463:Barbiturates / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D008297:Male; D010808:Physical Examination; D011164:Porphyrias / Q000139:chemically induced* / Q000145:classification / Q000188:drug therapy
D001463:Barbiturates