Encephalopathy in infantile hepatic cirrhosis.
The cases are described of two sibs who developed hepatic cirrhosis in early infancy, accompanied by profound mental retardation. Post mortem in one sib there were multiple foci of demyelination with abundant cellular infiltration, scattered throughout the brain. These unusual pathological changes are briefly commented.
D001344:Autopsy; D002648:Child; D003711:Demyelinating Diseases / Q000150:complications* / Q000473:pathology; D006801:Humans; D008607:Intellectual Disability / Q000150:complications* / Q000473:pathology; D008103:Liver Cirrhosis / Q000150:complications* / Q000473:pathology; D008297:Male