[Glutamate dehydrogenase activity in motor cortex neurons during restoration of disrupted visual function].
The recovery of the visual function of rats throughout two weeks after deprivation period (keeping animals in dark chambers for 8 weeks from their birth) leads to a significant normalization of the activity level of glutomatedehydrogenase in the neurones of the III and V layers of the motor cortex. The changes of the enzyme activity in the neurones are accompanied by a diminution of their sizes. The obtained data together with the results of the previous studies (Busnuk, 1976), suggest that the elimination of the visual impulse activity in the early ontogenesis exerts a specific and reversible influence on the morpho-chemical differentiation of neurones both in the visual and in the motor cortical areas. The functional factors determining the direction of changes in the studied parameters of cortical neurones during deprivation and in the rate of their normalization during recovery of the visual function are discussed.
D000818:Animals; D005969:Glutamate Dehydrogenase / Q000378:metabolism*; D009044:Motor Cortex / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D012683:Sensory Deprivation; D014785:Vision, Ocular / Q000502:physiology*
D005969:Glutamate Dehydrogenase
Aktivnost' gliutamatdegidrogenazy v neĭronakh dvigatel 'noĭ kory pri vosstanovlenii narushennoĭ zri tel 'noĭ funktsii.