title: [Extraosseous Ewing's sarcoma].
abstract: A 18 years old female patient was admitted to our clinic with a diagnosis of non-Hodgkin malignant lymphoma originating from the subcutaneous tissue of the left paravertebral region. Notwithstanding cycles of polychemotherapy and radiotherapy, clinical conditions rapidly worsened with rapid appearance of an increasing number of cutaneous neoplastic infiltrations. Due to the rapid spread of the malignancy -- as shown by lung X-rays and bone marrow biopsy -- the patient died 8 months after the onset of the disease (2 months after admittance). At autopsy, tumor cell infiltrates were found not only in the bone marrow and lung but also in the liver, adrenals, gonads and spinal cord. Histological and cytochemical features -- both in bioptic and autopic tissue specimens -- were quite similar to those of Ewing's sarcoma of bone. On the whole, of these clinical and histopathological features, this can be considered a case of "extraskeletal Ewing's sarcoma" as described by Angervall and Enzinger and recently by E. H. Soule et Al.
mesh_terms: D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000473:pathology / Q000556:secondary; D000311:Adrenal Glands / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology; D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary; D010051:Ovarian Neoplasms / Q000473:pathology / Q000556:secondary; D010053:Ovary / Q000473:pathology; D012512:Sarcoma, Ewing / Q000473:pathology / Q000556:secondary; D012983:Soft Tissue Neoplasms / Q000473:pathology; D013116:Spinal Cord / Q000473:pathology
vernacular_title: Sarcoma di Ewing extrascheletrico.