The reduction of 5 alpha-cholestan-3-one and 5 beta-cholestan-3-one by some boranes and hydroborates.
This paper describes the high yield synthesis of 5 alpha-cholestan-3 alpha-ol and 5 beta-cholestan-3 beta-ol by the reduction of 5 alpha- and 5 beta-cholestan-3-one using using potassium and lithium-tri-sec-butyl-hydroborates as reducing reagents. Attempts to obtain the same alcohols using other bulky boranes resulted in the equatorial products.
D001880:Boranes; D001894:Borohydrides; D002776:Cholestanes; D002777:Cholestanols; D002778:Cholestanones; D008722:Methods; D010084:Oxidation-Reduction
D001880:Boranes; D001894:Borohydrides; D002776:Cholestanes; D002777:Cholestanols; D002778:Cholestanones