Response to starvation before and after a jejuno-ileal bypass operation for morbid obesity.
A greater metabolic response developed during a seven day starvation in two morbidly obese patients three months after a 90 per cent jejuno-ileal bypass operation when compared with a similar fast before operation. There was a greater degree of ketosis, a decreased urinary urea excretion and an earlier utilization of ketone bodies. These changes suggest a metabolic adaptation of the body to the semistarvation state caused by the operation with a more rapid utilization of adipose tissue as a fuel and a sparing of lean body mass.
D000328:Adult; D004038:Diet, Reducing; D005260:Female; D006801:Humans; D007082:Ileum / Q000601:surgery; D007421:Intestine, Small / Q000601:surgery*; D007583:Jejunum / Q000601:surgery; D007662:Ketosis / Q000378:metabolism; D009765:Obesity / Q000178:diet therapy / Q000378:metabolism / Q000628:therapy*; D013217:Starvation / Q000378:metabolism*