Modulatory effects of the amygdala on oestrogen-induced LH secretion in ovariectomized rats.
An increase in LH secretion was induced in ovariectomized oestradiol benzoate-primed rats 5 h after a second injection of oestradiol benzoate. Lesions stereotaxically placed in the cortical and basomedial amygdala of steroid-primed rats abolished this rise. The results provide evidence for a facilitatory action of the amygdala upon LH release and an involvement of this region of the limbic system in oestrogen-feedback mechanisms.
D000679:Amygdala / Q000502:physiology*; D000818:Animals; D002369:Castration; D004958:Estradiol / Q000494:pharmacology*; D005246:Feedback; D005260:Female; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism*; D051381:Rats; D013268:Stimulation, Chemical
D004958:Estradiol; D007986:Luteinizing Hormone