title: [Activation of prekallikrein from human blood serum by different activators].
abstract: It was shown that the activated Hageman factor and its active fragment convert a greater amount of prekallikrein into kallikrein than is observed under the effects of trypsin and kallikrein. The latter two enzymes convert from 30 to 60% of the Hageman factor-activated prekallikrein and its active fragment. A possible existence of two prekallikrein forms is discussed. A mechanism of interaction between individual components of the kininogenase system and their activators is discussed.
mesh_terms: D004789:Enzyme Activation; D005174:Factor XII / Q000378:metabolism; D006801:Humans; D007610:Kallikreins / Q000378:metabolism*; D007700:Kinetics; D011288:Prekallikrein / Q000378:metabolism*
chemical_list: D005174:Factor XII; D011288:Prekallikrein; D007610:Kallikreins
vernacular_title: Aktivirovanie prekallikreina syvorotki krovi cheloveka razlichnymi aktivatorami.