title: A pocket of controlled malaria in a holoendemic region of West Africa.
abstract: Yekepa, a mining town in northern Liberia, has been built entirely since 1960 and now has a population of 16 000 inhabitants including 1500 expatriates. Although situated in a holoendemic region with constant human movements in and out of the town, the mining company has succeeded in controlling malaria in Yekepa. Furthermore, there is a constant threat of the vector in the close surroundings to the town. Control is maintained by regular residual insecticide sprayings with DDT, regular larviciding with fuel oil and fortnightly issue of amodiaquine chemoprophylactic to all workers. A Malariometric survey showed that the spleen and parasite rates were 11% and 13% respectively in the controlled areas and 95% and 67% respectively in surrounding regions not subjected to control measures. The dominant malaria parasite in the area was Plasmodium falciparum. No adult vectors were found in the town. In the surrounding villages the average room density of adult vectors was 3.8 and the sporozoite rate in a village very close to the town was 9.2%. The dominant vector of the area was Anopheles gambiae with A. Funestusalso being present. The annual per capita cost, including all control activities, is about 4--5 US dollars.
mesh_terms: D000655:Amodiaquine / Q000627:therapeutic use; D000852:Anopheles / Q000469:parasitology; D002648:Child; D002675:Child, Preschool; D002738:Chloroquine / Q000627:therapeutic use; D003365:Costs and Cost Analysis; D006801:Humans; D007988:Liberia; D008288:Malaria / Q000191:economics / Q000469:parasitology / Q000517:prevention & control*; D009032:Mosquito Control / Q000379:methods; D010961:Plasmodium; D013163:Splenomegaly / Q000469:parasitology
chemical_list: D000655:Amodiaquine; D002738:Chloroquine