Modification of metoclopramide GLC assay: application to human biological specimens.
A modified electron-capture GLC assay for metoclopramide in human biological specimens is reported. This assay involves the incorporation of a back-extraction method to remove endogenous contaminants. Its applicability was demonstrated by studying the time course of metoclopramide in plasma and urine from a human subject. The lowest quantifiable metoclopramide concentration in plasma was 7 ng/ml, provided 0.5 ml of plasma was used.
D002849:Chromatography, Gas; D006207:Half-Life; D006801:Humans; D008722:Methods; D008787:Metoclopramide / Q000032:analysis* / Q000097:blood / Q000652:urine; D013997:Time Factors
D008787:Metoclopramide