Ampicillin resistant Haemophilus parainfluenzae endocarditis.
A case of Haemophilus parainfluenzae bacterial endocarditis is described. This is the first reported case of endocarditis caused by ampicillin resistant H parainfluenzae. Resistance was not mediated by a beta lactamase. Ampicillin therapy had not controlled the infection, but a four-week course of chloramphenicol was curative. Several general therapeutic points are discussed.
D000328:Adult; D000667:Ampicillin / Q000494:pharmacology*; D002701:Chloramphenicol / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D006190:Haemophilus / Q000187:drug effects*; D006192:Haemophilus Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D010403:Penicillin Resistance
D002701:Chloramphenicol; D000667:Ampicillin