title: [Effect of preovulatory overripeness of the ovum on the course of the early stages of rat embryogenesis].
abstract: One day delay of ovulation in rats, caused by the injection of medinal, resulted in the marked slowing down of the cleavage rate. The delay is due to additive effect of both the drug itself and preovulatory over-ripeness of the oocytes. Upon two days medinal delay of ovulation, the toxic effect of over-ripeness was not stronger than upon the twofold injection of medinal; two days hormonal delay of ovulation resulted in the distinct inhibition of cleavage.
mesh_terms: D000818:Animals; D001462:Barbital / Q000494:pharmacology; D002454:Cell Differentiation / Q000187:drug effects; D003864:Depression, Chemical; D004627:Embryonic Induction / Q000187:drug effects; D005260:Female; D010060:Ovulation / Q000187:drug effects; D010063:Ovum / Q000187:drug effects / Q000502:physiology*; D011247:Pregnancy; D011359:Proestrus / Q000187:drug effects; D051381:Rats; D013997:Time Factors
chemical_list: D001462:Barbital
vernacular_title: Vliianie preovultiatornogo perezrevaniia iaĭtsekletok na techenie rannikh stadiĭ émbriogeneza krys.