The correlation between hypertension in past history and the incidence of cerebral aneurysms.
The incidence of hypertension in past history was investigated in 811 cases of cerebral aneurysm. These cases were compiled from 1,000 cases of saccular aneurysm in which direct surgical operations for aneurysm were performed at our clinic during the period from June 1961 to September 1975. Of the 811 cases, 365 (45%) had hypertension in their past history; 185 (42.7%) out of 433 males and 180 (47.6%) out of 378 females. In the 5th decade of age, the incidence was significantly higher in the females than in the males, but no difference by sex was noted in other age groups. In the males from the 3rd to the 7th decade, the number of hypertensives increased significantly with advancing age, whereas in the females a significant difference was observed only between the 4th and 7th decades, the latter including more hypertensives. The incidence of hypertensives in the aneurysm cases was compared with that in the Japanese population reported by Sasaki. This comparison revealed that in both sexes between the 4th and 6th decades, the incidence was significantly higher in the former, whereas no significant difference was noted between the two in the 7th decade. As to the location of aneurysms, only the multiple aneurysms group had a significantly greater number of hypertensives than single aneurysm group. These results agree with previous reports that cerebral aneurysm may occur more frequently in the hypertensives than in the normotensives.
D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D002532:Intracranial Aneurysm / Q000453:epidemiology* / Q000209:etiology; D007564:Japan; D008297:Male; D008875:Middle Aged