Polioencephalomalacia (cerebrocortical necrosis) induced by experimental thiamine deficiency in lambs.
Lesions of polioencephalomalacia (PEM, cerebrocortical necrosis) have been demonstrated in pre-ruminant lambs fed on synthetic, thiamine-free milk. Thiamine deficiency in these lambs was confirmed by transketolase assay.
D000818:Animals; D001921:Brain / Q000473:pathology; D004678:Encephalomalacia / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D009336:Necrosis; D012756:Sheep; D012757:Sheep Diseases / Q000209:etiology / Q000473:pathology*; D013832:Thiamine Deficiency / Q000150:complications / Q000662:veterinary*