[Description of the ratios between metabolite concentrations in a polyenzyme system].
It was demonstrated that the relations between substrate and product concentrations for a reaction catalyzed by michaelian enzyme incorporated in a multienzyme system can be graphically represented by a diverging set of straight lines intersecting in one point, the flux velocity being treated as a parameter. A competitive inhibitor shifts the intersection point along the line of equilibrium state. The relations between the concentrations of more than two reagents are represented by a set of equivelocity surfaces. The relations between substrate and product concentrations for a kinetically cooperative reaction conforming to the graphical representation by the second--order curves were analyzed. The stability criterion was obtained for a multienzyme system with the first enzyme allosterically regulated by products of subsequent reactions.
D000494:Allosteric Regulation; D001667:Binding, Competitive; D002384:Catalysis; D004791:Enzyme Inhibitors; D004798:Enzymes; D007700:Kinetics; D008956:Models, Chemical
D004791:Enzyme Inhibitors; D004798:Enzymes
Opisanie sootnosheniĭ mezhdu kontsentratsiiami metabolitov v polifermentnoĭ sisteme.