Ocular Toxocara in siblings of two families. Diagnosis confirmed by ELISA test.
To my knowledge this study of two families with ocular Toxocara is the first in the literature to report involvement of more than one sibling. All four children had far-advanced disease with irreversible loss of macular vision in the affected eye. The clinical findings were confirmed by the ELISA test. With laboratory confirmation of the clinical findings, I expect to find not only more patients in the population at large with ocular Toxocara, but also expect to find numerous siblings in a particular family to be involved as well. Therefore, when ocular Toxocara is found in a child, every sibling in the family should be examined. Just as the young child with amblyopia does not complain of decreased vision, even so the young child with ocular Toxocara often will not complain of any visual problems.
D001196:Ascariasis / Q000235:genetics*; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005128:Eye Diseases / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D014120:Toxocariasis / Q000175:diagnosis / Q000235:genetics*