Steroid and prostaglandin secretion by the corpus luteum, endometrium and embryos of cyclic and pregnant pigs.
Prostaglandin F2 alpha (PGF2 alpha) secreted by the reproductive tissues of the pig in vitro was measured and it was found that the levels secreted by the corpus luteum and endometrium of early pregnant sows were significantly lower than those secreted by tissues during the late stage of the oestrous cycle. They were, however, comparable to levels secreted by tissues from the mid-stage of the oestrous cycle. Embryos also secreted significant amounts of PGF2 alpha. Secretion of progesterone and oestradiol by the corpora lutea of both cyclic and pregnant pigs fell within accepted limits but embryos were also found to secrete significant amounts of oestradiol. The results suggest that luteal maintenance in the early pregnant pig is unlikely to be directly due to reduced synthesis of PGF2 alpha.
D000818:Animals; D003338:Corpus Luteum / Q000378:metabolism*; D004622:Embryo, Mammalian / Q000378:metabolism*; D004717:Endometrium / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism; D004971:Estrus; D005260:Female; D011247:Pregnancy; D011270:Pregnancy, Animal; D011374:Progesterone / Q000378:metabolism; D011460:Prostaglandins F / Q000378:metabolism*; D013552:Swine / Q000502:physiology*
D011460:Prostaglandins F; D011374:Progesterone; D004958:Estradiol