[Experimental studies of parmidin (pyridinolcarbamate) effect on microvascular permeability of the lungs, skin and mesentery].
The effect of parmidin (pyridinolcarbamate) on microvascular permeability of several organs has been studied on experimental mice and rats using different models of increased vascular permeability, returned to normal by the drug due to its antibradykinine properties. The experimental results correlate with the clinical data on parmidin applied in therapy of a number of diseases associated with abnormal microcirculation.
D000818:Animals; D002219:Carbamates / Q000494:pharmacology*; D008297:Male; D008643:Mesentery / Q000098:blood supply* / Q000187:drug effects; D051379:Mice; D008833:Microcirculation / Q000187:drug effects / Q000502:physiology*; D011652:Pulmonary Circulation / Q000187:drug effects*; D011727:Pyridinolcarbamate / Q000494:pharmacology*; D051381:Rats; D012867:Skin / Q000098:blood supply* / Q000187:drug effects
D002219:Carbamates; D011727:Pyridinolcarbamate
Vliianie parmidina (piridinolkarbamata) na pronitsaemost' mikrososudov legkikh, kozhi i bryzheĭki v eksperimente.