[Inhibitory effect of methergoline on serotonin induced contraction of isolated strips of coronary arteries].
Metergoline (antiserotonin drug) prevents the contraction induced by serotonin on strips of isolated coronary arteries. Moreover when metergoline is added at the maximal contraction, it induces relaxation of the vascular smooth muscle preceeded by a brevious phase of contraction.
D000818:Animals; D002417:Cattle; D003331:Coronary Vessels / Q000187:drug effects*; D004873:Ergolines / Q000494:pharmacology*; D008711:Metergoline / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects*; D009131:Muscle, Smooth, Vascular / Q000187:drug effects; D012701:Serotonin / Q000494:pharmacology*; D012702:Serotonin Antagonists
D004873:Ergolines; D012702:Serotonin Antagonists; D008711:Metergoline; D012701:Serotonin
Effetto inibitorio della metergolina sulla contrazione indotta da serotonina, di segmenti di arterie coronarie isolate.