[Action of heavy water on actomyosin pellicular filaments].
Deuterium oxide (D2O) prolongates the contractile ability of actomyosin threads by 85%. The contraction of actomyosin threads decreases in the presence of D2O by 28%. D2O decreases neutral red sorption by actomyosin threads. The limiting dye sorption (A infinity) decreases by 45 and 31% within the ranges of weak and high concentrations, resp. Thus, deuterium oxide may affect the conformation of protein molecules.
D000042:Absorption; D000205:Actomyosin / Q000494:pharmacology*; D000818:Animals; D003903:Deuterium; D004347:Drug Interactions; D066298:In Vitro Techniques; D008968:Molecular Conformation; D009119:Muscle Contraction / Q000187:drug effects; D009499:Neutral Red / Q000494:pharmacology; D011189:Potassium Chloride / Q000494:pharmacology; D011817:Rabbits; D013997:Time Factors; D014867:Water / Q000494:pharmacology
D014867:Water; D009499:Neutral Red; D011189:Potassium Chloride; D000205:Actomyosin; D003903:Deuterium
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