Host-parasite relations in cotton rat filariasis. III. The quantitative transmission of Litomosoides carinii to un-irradiated and irradiated golden hamsters and white mice.
The quantitative transmission of Litomosoides carinii by Liponyssus bacoti to un-irradiated and irradiated hamsters and mice is described. Both young and adult, un-irradiated and irradiated hamsters were highly susceptible to L. carinii but mice (un-irradiated or irradiated) were poor hosts. All hamsters (18 un-irradiated and seven irradiated) became infected. Seven out of nine mice in an un-irradiated series became infected. There was apparently 'age resistance' or 'young susceptibility' in the hamsters. The susceptibility of young hamsters appeared similar to that of new-born Carworth white rats and cotton rats. The pattern of infection in un-irradiated and irradiated hamsters was similar. Results from irradiated animals were insufficient to draw any clear conclusions on the effect of irradiation to susceptibility to infection with L. carinii. X-irradiation apparently did not affect the innate susceptibility cr resistance of hamsters and mice to worms. The duration and intensity of microfilaraemia was apparently higher in irradiated hamsters.
D000818:Animals; D006224:Cricetinae; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005368:Filariasis / Q000276:immunology / Q000469:parasitology / Q000635:transmission*; D005370:Filarioidea / Q000254:growth & development*; D006790:Host-Parasite Interactions; D007113:Immunity, Innate / Q000528:radiation effects*; D008297:Male; D008647:Mesocricetus; D051379:Mice; D008925:Mites / Q000469:parasitology; D051381:Rats