Intercellular adhesion as a function of the cell cycle traverse.
Intercellular adhesion is assumed to play an important role in a multitude of biological phenomena governing cellular behavior. The rate of intercellular adhesion as a function of the cell cycle traverse has been investigated using, in the monolayer assay, synchronized Chinese Hamster Ovary-K1 cells. Results obtained demonstrate that cells in G1 adhere to G1 cells at twice the rate that S cells adhere to each other. G1 cells adhere to S cells at an intermediate rate. The additive adhesiveness seen in G1 is abolished by brief trypsinization, suggesting that in G1 a qualitative or quantitative change occurs with respect to the presence or exposure of components involved in intercellular adhesion.
D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects; D002453:Cell Cycle; D002460:Cell Line; D002469:Cell Separation; D006224:Cricetinae; D005260:Female; D007399:Interphase; D010053:Ovary; D014357:Trypsin / Q000494:pharmacology
D014357:Trypsin