[Changes in the spike activity of vagus nerves following stimulation of the anticlotting system].
In rabbits, changes of electrical activity of the n. vagus liver branches were studied during i. v. administration of thrombin and perfusion of the isolated carotid sinus, during the reflex response of the anticoagulating blood system. The efferent vagus activity raised to the maximal level within 3--10 min after i. v. administration or after perfusion, coinciding in time with the maximal effect of the hypocoagulation. The augmentation of the activity depended on amount of thrombin. The similarity of effects of the perfusion and i. v. thrombin suggests the same efferents for the reflex response of the anticoagulating blood system passing through the vagus.
D000818:Animals; D001777:Blood Coagulation; D002346:Carotid Sinus / Q000187:drug effects*; D004594:Electrophysiology; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D005342:Fibrinolysis / Q000187:drug effects; D008099:Liver / Q000294:innervation*; D008297:Male; D009476:Neurons, Efferent / Q000502:physiology; D011817:Rabbits; D013917:Thrombin / Q000494:pharmacology*; D013918:Thrombin Time; D014630:Vagus Nerve / Q000502:physiology*; D014914:Whole Blood Coagulation Time
D005340:Fibrinogen; D013917:Thrombin
Izmenenie impul'snoĭ aktivnosti bluzhdaiushchikh nervov pri vozbuzhdenii protivosvertyvaiushcheĭ sistemy.