Influence of classic immunosuppressants on spleen colony formation in mice. 3. Concentration of colony forming units in bone marrow and spleens of cyclophosphamide-treated mice.
The concentration of colony forming units (CFU) increased nonsignificantly in bone marrow, and significantly in spleens of cyclophosphamide-treated mice, but there was no increase in the absolute number of CFU in these organs due to decreased celullarity. The serum of mice pretreated with cyclophosphamide seems to have colony-stimulating activity.
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects* / Q000528:radiation effects; D001854:Bone Marrow Cells; D003114:Colony-Forming Units Assay; D003520:Cyclophosphamide / Q000494:pharmacology*; D006410:Hematopoiesis / Q000187:drug effects* / Q000528:radiation effects; D008297:Male; D051379:Mice; D013154:Spleen / Q000166:cytology / Q000187:drug effects / Q000528:radiation effects
D003520:Cyclophosphamide