title: [Irrigation of the internal organs and the effect of the protein hydrolysate, Hydroport, in deep burns in rats].
abstract: The authors caused buring of III to IV degree, 10--15% in rats of the Wistar strain. The animals were divided into 4 groups: 1) healthy; 2) burned-nontreated; 3) burned-treated with saline; and 4) burned-treated with hydrolysate. Saline and hydrolysate were administered immediately after thermic trauma, and vascularization was examined by means of radioisotopic methods (86Rb) six hours after burning. Increased blood flow in the internal organs was found 6 hours after inducing the thermic trauma, excluding the pancreas. Saline revealed a certain tendency to normalization of the circulation, but this effect was insignificant and could not be referred to all organs. The protein hydrolysate most sensitively and significantly corrected deviations as in almost all organs they reached practically the norm.
mesh_terms: D000818:Animals; D002056:Burns / Q000628:therapy*; D004353:Drug Evaluation, Preclinical; D011492:Protein Hydrolysates / Q000627:therapeutic use*; D051381:Rats; D012039:Regional Blood Flow / Q000187:drug effects; D007507:Therapeutic Irrigation
chemical_list: D011492:Protein Hydrolysates
vernacular_title: Orosiavane na vutreshnite organi i negovoto povliiavane ot beltuchen khidrolizat Khidroport pri dulboko izgariane na plukhove.