title: ADS-12: an automated programmable 12-tablet dissolution testing system.
abstract: A novel computerized automated system is described which conforms to the basic requirements set forth in the compendia for testing the dissolution characteristics of solid dosage forms. This modular system can test 12 tablets simultaneously. It can maintain sink conditions at all times and can handle any chemistry amenable to an automatic analyzer. Dissolution, sampling, chemistry, and readout are all accomplished simultaneously, reducing the complete test time for 12 tablets to the dissolution time itself.
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000295:instrumentation; D003201:Computers; D004917:Erythromycin / Q000032:analysis; D010400:Penicillin G / Q000032:analysis; D011241:Prednisone / Q000032:analysis; D012459:Salicylates / Q000032:analysis; D012995:Solubility; D013056:Spectrophotometry, Ultraviolet; D013607:Tablets
chemical_list: D012459:Salicylates; D013607:Tablets; D004917:Erythromycin; D010400:Penicillin G; D011241:Prednisone