Effects of d-amphetamine and caffeine on schedule-controlled and schedule-induced responding.
The effects of d-amphetamine and caffeine were studied on rates and patterns of lever pressing and schedule-induced licking under fixed-interval schedules of food pellet presentation. In addition, the effects of caffeine were studied on lever pressing and licking under a multiple fixed-ratio fixed-interval schedule. Caffeine reduced mean overall rates of licking at lower doses than it reduced mean overall rates of pressing under the fixed-interval schedules, but the effects of caffeine on both licking and lever pressing depended largely on the control rate of responding. d-Amphetamine reduced mean overall rates of lever pressing and licking at about the same dose, but the effects of d-amphetamine also were a function of the control rate of responding.
D000818:Animals; D002110:Caffeine / Q000494:pharmacology*; D003216:Conditioning, Operant / Q000187:drug effects*; D003913:Dextroamphetamine / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004326:Drinking / Q000187:drug effects; D008297:Male; D051381:Rats; D012055:Reinforcement Schedule
D002110:Caffeine; D003913:Dextroamphetamine