Polymorphism of alanine aminotransferase (E.C.2.7.6.1): common and rare alleles.
Gene frequencies of common and rare GPT alleles derived from an investigation of 1139 unrelated, healthy individuals from southwestern Germany are given. GPT typing was performed by means of horizontal starch gel electrophoresis in a Tris-histidine x HCl buffer system. In addition, a new electrophoretic variant, GPT9, is described. The frequencies of the GPT alleles observed were calculated as: GPT1, 0.4987; GPT2, 0.4686; GPT1M, 0.022; GPT0, 0.005; GPT3, 0.0022; GPT4, 0.0025; GPT8, 0.0005; GPT9, 0.0005.
D000410:Alanine Transaminase / Q000097:blood / Q000235:genetics*; D000483:Alleles; D004592:Electrophoresis, Starch Gel; D005787:Gene Frequency; D005860:Germany, West / Q000208:ethnology; D006801:Humans; D010641:Phenotype; D011110:Polymorphism, Genetic
D000410:Alanine Transaminase