Synthesis of a cytotoxic insulin cross-linked to diphtheria toxin fragment A capable of recognizing insulin receptors.
D000818:Animals; D002460:Cell Line; D004167:Diphtheria Toxin / Q000378:metabolism* / Q000494:pharmacology; D004220:Disulfides; D007328:Insulin / Q000378:metabolism* / Q000494:pharmacology; D007700:Kinetics; D051379:Mice; D008809:Mice, Inbred C3H; D014176:Protein Biosynthesis / Q000187:drug effects; D011972:Receptor, Insulin / Q000378:metabolism*
D004167:Diphtheria Toxin; D004220:Disulfides; D007328:Insulin; D011972:Receptor, Insulin