title: Rheological properties of skin components under compressive load.
abstract: Characterization was made of the mechanical properties under compression of four major skin components (collagen, elastin, chondroitin sulfate, and hyaluronic acid) placed in a gel matrix. Using the previous theoretical work of Bert et al., thickness under compression was related to degree of hydration and the results expressed in terms of pressure vs. hydration. All measurements were conducted at 14 degrees C, 21 degrees C, and 25 degrees C. Application of the findings to a model based on the finite deformation strain-energy theory of Aubert indicate that collagen, elastin, and chondroitin sulfate show a viscoelastic response under compression. On the other hand, hyaluronic acid and gelatin exhibit rubber-like behavior.
mesh_terms: D002807:Chondroitin / Q000031:analogs & derivatives*; D002809:Chondroitin Sulfates / Q000502:physiology*; D003094:Collagen / Q000502:physiology*; D003187:Compliance; D004548:Elasticity; D004549:Elastin / Q000502:physiology*; D006801:Humans; D006820:Hyaluronic Acid / Q000502:physiology*; D008433:Mathematics; D008954:Models, Biological; D008968:Molecular Conformation; D011312:Pressure
chemical_list: D006820:Hyaluronic Acid; D002807:Chondroitin; D002809:Chondroitin Sulfates; D003094:Collagen; D004549:Elastin