title: Effect of fiber and dye degradation products (FDP) on burn wound healing.
abstract: Upon exposure to the thermal environment of an aircraft fire, many fire retardant fabrics off-gas fiber and dye degradation products (FDP). Condensation of these products on human skin raises questions concerning possible deleterious effects on burn wound healing. A porcine bioassay was used to study the physiological effects of FDP. Selected areas of living skin, protected by dyed aromatic polyamides and polybenzimidazole fabrics, were exposed to a thermal source adjusted to simulate a postcrash JP-4 fuel fire. Burn sites contaminated with FDP were evaluated by clinical observation ane to begin epithelialization, time to closure of an open wound, and the amount and type of cicatrix formation. The experiment showed that each fabric has unique off-gasing products. The greatest amount of FDP was deposited on the skin when the skin was covered by a single layer of shell fabric separated by a 6.35-mm air gap. The presence of an intervening cotton T-shirt decreased the amount of FDP deposited on the skin. We found no evidence that FDP caused alterations in wound healing.
mesh_terms: D000337:Aerospace Medicine; D000818:Animals; D002056:Burns / Q000503:physiopathology*; D004396:Coloring Agents / Q000009:adverse effects*; D005411:Flame Retardants / Q000009:adverse effects*; D011481:Protective Clothing; D013552:Swine; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D004396:Coloring Agents; D005411:Flame Retardants