Hepatic microsomal biotransformation of 1,3,5(10),16-estratetraen-3-o1 to 16,17-epiestriol and estriol via 16 alpha,17 alpha- and 16 beta,17 beta-epoxy-1,3,5(10)-estratrien-3-ols.
D000818:Animals; D002248:Carbon Monoxide / Q000494:pharmacology; D002849:Chromatography, Gas; D004852:Epoxy Compounds / Q000378:metabolism; D004963:Estrenes / Q000378:metabolism*; D004964:Estriol / Q000031:analogs & derivatives* / Q000378:metabolism*; D005260:Female; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008797:Metyrapone / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D011335:Proadifen / Q000494:pharmacology; D051381:Rats; D013237:Stereoisomerism
D004852:Epoxy Compounds; D004963:Estrenes; C021673:16 beta,17 beta-epoxy-1,3,5(10)-estratrien-3-ol; D002248:Carbon Monoxide; D011335:Proadifen; D004964:Estriol; D008797:Metyrapone