Evaluation of a new diagnostic kit for the enzymatic determination of creatinine.
We have evaluated a new diagnostic kit for the enzymatic determination of creatinine in serum, plasma and urine. The method was found to be linear up to 1000 mumol/l. Within-run precision had a coefficient of variation of 3.1--5.6% for normal to slightly elevated values and of 2.3--3.3% for values of about 320 mumol/l. Day-to-day precision was found to be 7.8 and 5.7% for values of 94 and 141 mumol/l, respectively. Mean analytic recovery was 98%. Bilirubin and hemoglobin did not interfere in concentrations up to 490 and 240 mumol/l, respectively. The influence of lipids was studied. Correlation studies were done with two other methods, the Technicon SMA 12/60 method and the Dutch standard manual method.
D000581:Amidohydrolases; D001322:Autoanalysis; D001663:Bilirubin / Q000097:blood; D003404:Creatinine / Q000097:blood* / Q000652:urine; D006454:Hemoglobins; D006801:Humans; D011933:Reagent Kits, Diagnostic; D013056:Spectrophotometry, Ultraviolet / Q000379:methods
D006454:Hemoglobins; D011933:Reagent Kits, Diagnostic; D003404:Creatinine; D000581:Amidohydrolases; D001663:Bilirubin