title: Intradermal skin tests with Dermatophagoides pteronyssinus in asthmatic children: correlation with specific IgE and bronchial provocation tests.
abstract: The purpose of the present study was to compare the results of the skin tests, the specific IgE levels and bronchial provocation tests in a group of sensitive asthmatic children with a Dermatophagoides pteronyssinus extract standardized by the RAST inhibition method. Skin tests showed a positive 'end point' in twelve children of 0.5 U/ml antigen; in eleven 5 U/ml; seven of 50 U/ml; six of 500 U/ml. Specific IgE was present in thirty-three children (92%). A close relationship between positive skin tests and serum IgE levels was found. Bronchial provocation tests were positive in twenty-eight children (78%): eight children with both positive RAST and positive skin tests had negative bronchial provocation tests.
mesh_terms: D000293:Adolescent; D000485:Allergens; D001249:Asthma / Q000276:immunology*; D001666:Binding Sites, Antibody; D001980:Bronchi / Q000276:immunology; D001985:Bronchial Provocation Tests; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D007428:Intradermal Tests; D008297:Male; D008925:Mites; D011852:Radioallergosorbent Test; D012882:Skin Tests
chemical_list: D000485:Allergens; D007073:Immunoglobulin E