[Effect of a carcinogen on the electric activity of the rat stomach].
Acute experiments on rats showed that the intragastric administration of an aqueous solution of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) elicited depression of the electrical activity of the gastric wall manifested by a decrease in the amplitude and frequency of the basic electrical rhythm and by its complete stopping in most cases. MNNG abolished the excitatory reaction caused both by the vagal electric stimulation and administration of carbacholine, but there persists an inhibitory reaction elicited both by the vagal stimulation and infusion of ATP.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D003864:Depression, Chemical; D004558:Electric Stimulation; D008769:Methylnitronitrosoguanidine / Q000494:pharmacology*; D011708:Pylorus / Q000294:innervation*; D051381:Rats; D014630:Vagus Nerve / Q000502:physiology*
D008769:Methylnitronitrosoguanidine
Vliianie kantserogena na élektricheskuiu aktivnost' zheludka krys.