Effects of intravenous administration of brain phospholipids on gonadotropin release in man.
Administration of 600 mg of brain phospholipids i.v. in normal adult volunteers results in a significant decrease of the testosterone circulating levels. This phenomenon is not accompanied by a modification in gonadotropin quantitative levels, but by a reduction in LH pulsatility. This seems to be important for the peripheral biological activity of LH.
D000328:Adult; D001923:Brain Chemistry; D005640:Follicle Stimulating Hormone / Q000097:blood; D006062:Gonadotropins / Q000378:metabolism*; D006801:Humans; D007275:Injections, Intravenous; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010743:Phospholipids / Q000008:administration & dosage / Q000494:pharmacology*; D013739:Testosterone / Q000097:blood; D013997:Time Factors
D006062:Gonadotropins; D010743:Phospholipids; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone