title: Rebound nystagmus: EOG analysis of a case with a floccular tumour.
abstract: Eye movements were recorded and quantitatively analysed in a patient with a tumour initially involving the cerebellar flocculus. Ocular motor abnormalities included (1) impaired smooth pursuit, (2) impaired cancellation of the vestibulo-ocular reflex when fixating an object rotating with the head, and (3) gaze paretic and rebound nystagmus. Comparable findings have been reported in monkeys with experimental floccular lesions. The rebound nystagmus (but not the other ocular motor abnormalities) disappeared when the tumour appeared to invade the brain stem in the region near the vestibular nuclei. This finding suggests that the floccular lesion unmasked a bias which created rebound nystagmus and that the bias probably arose in the vestibular nuclei.
mesh_terms: D000293:Adolescent; D002150:Caloric Tests; D002528:Cerebellar Neoplasms / Q000150:complications* / Q000601:surgery; D004585:Electrooculography; D005260:Female; D006801:Humans; D009759:Nystagmus, Pathologic / Q000150:complications* / Q000175:diagnosis; D010212:Papilloma / Q000150:complications* / Q000601:surgery; D012438:Saccades