title: [Nosologic isolation of involutional depressions and features of their dynamics during psychopharmacotherapy].
abstract: Clinical follow-up studies of 92 patients registered in a psychiatric dispensary with involutional depression confirmed the diagnosis only in 51 cases. Some clinical features in the hereditary loading, premorbid personality traits and premanifest symptoms in patients with a confirmed diagnosis during follow-up examinations were demonstrated. Variants in the development of the clinical picture, related to signs of therapeutic pathomorphosis and due to long-term psychopharmacotherapy were eliminated. An underestimation of this circumstance may lead to an unjustified narrowing of the limits of involutional depression.
mesh_terms: D000328:Adult; D000342:Affective Symptoms / Q000175:diagnosis; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000188:drug therapy; D003951:Diagnostic Errors; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000175:diagnosis; D012559:Schizophrenia / Q000175:diagnosis; D012563:Schizophrenia, Paranoid / Q000175:diagnosis; D013577:Syndrome; D014149:Tranquilizing Agents / Q000627:therapeutic use*
chemical_list: D000928:Antidepressive Agents; D014149:Tranquilizing Agents
vernacular_title: K voprosu o nozologicheskom obosoblenii involiutsionnykh depressiĭ i osobennostiakh ikh dinamiki pri psikhofarmakoterapii.