Antibodies to the acetylcholine receptor in myasthenic dogs.
Antibodies to the AChR and anti-striational antibodies have been detected in dogs suffering from myasthenia gravis. The detection of these antibodies adds to the known similarities between the human and canine disease. This animal model will facilitate investigation of agents involved in the induction of spontaneous myasthenia gravis.
D000109:Acetylcholine / Q000276:immunology*; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D004195:Disease Models, Animal; D004283:Dog Diseases / Q000276:immunology*; D004285:Dogs; D005260:Female; D008297:Male; D008459:Measles virus / Q000276:immunology; D009157:Myasthenia Gravis / Q000276:immunology / Q000662:veterinary*; D011950:Receptors, Cholinergic / Q000276:immunology*
D000914:Antibodies, Viral; D001323:Autoantibodies; D011950:Receptors, Cholinergic; D000109:Acetylcholine