Damage to the biliary tract during preservation.
Biliary complications following liver transplantation continue to present major difficulties. Damage to the biliary tract has been reported after preservation of the liver before transplantation. Studies in the rabbit are reported that confirm the extensive biliary autolysis during preservation. This damage is directly related to the presence of bile in the biliary tract and can be reduced by the washout of bile and biliary perfusion.
D000818:Animals; D001329:Autolysis; D001659:Biliary Tract / Q000473:pathology*; D001798:Blood Proteins; D005704:Gallbladder / Q000473:pathology; D008099:Liver / Q000473:pathology; D009336:Necrosis; D010477:Perfusion; D011183:Postoperative Complications / Q000209:etiology; D011309:Preservation, Biological; D011817:Rabbits
D001798:Blood Proteins