p-Aminophenol fluorescence and determination in the presence of acetaminophen.
The spectrophotometric and fluorometric properties of the aminophenols and of several compounds related to p-aminophenol were examined. A direct spectrofluorometric method for p-aminophenol determination at trace levels in methanol was developed and evaluated for the effect of inner filtering by acetaminophen. The method was applied to the determination of p-aminophenol as an impurity in acetaminophen and acetaminophen-containing tablets.
D000082:Acetaminophen; D000627:Aminophenols / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D008722:Methods; D013050:Spectrometry, Fluorescence; D013607:Tablets / Q000032:analysis
D000627:Aminophenols; D013607:Tablets; D000082:Acetaminophen