title: Low risk of pelvic inflammatory disease in young never-pregnant women using Gravigard.
abstract: The present four-center investigation involves 516 never-pregnant women in whom a copper-7-intrauterine device (Cu-7-IUD) was inserted. Out of these patients 173 were teenagers at the time of insertion. A "small-sized" Cu-7-IUD (Cu-7-Nullip) - designed for nulliparous women - was randomely used instead of the commercially available Cu-7-IUD (GravigardR) in 76 - 44 of whom were teenagers - out of the 516 women. The incidence of pelvic inflammatory disease (PID) of 9,080 woman-months was reviewed. In the present study the incidence of PID varied from one center to another between 0.9  and 1.4 per cent/year in women wearing Cu-IUDs. When comparing these figures with the estimated incidence (1.2%) in the population of fertile-aged women, it was concluded that the risk for PID was not increased in never-pregnant women using Cu-IUDs, including teenagers as well as women of 20 years of age or more. No difference in the incidence of PID was observed between the GravigardR and the Cu-7 Nullip.
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging; D005260:Female; D006069:Gonorrhea / Q000150:complications; D006801:Humans; D007435:Intrauterine Devices, Copper / Q000009:adverse effects; D000292:Pelvic Inflammatory Disease / Q000209:etiology*; D011247:Pregnancy; D012306:Risk