title: A seventh complementation group in excision-deficient xeroderma pigmentosum.
abstract: Cells from a xeroderma pigmentosum patient XP2BI who has reached 17 years of age with no keratoses or skin tumours constitute a new, 7th complementation group G. These cells exhibit a low residual level of excision repair, 2% of normal after a UV dose of 5 J/m2 and an impairment of post-replication repair characteristic of excision-defective XPs. They are also sensitive to the lethal effects of UV and defective in host-cell reactivation of UV-irradiated SV40 DNA.
mesh_terms: D000293:Adolescent; D002478:Cells, Cultured; D004247:DNA / Q000528:radiation effects*; D004260:DNA Repair; D005260:Female; D005816:Genetic Complementation Test; D006801:Humans; D012867:Skin / Q000528:radiation effects; D014466:Ultraviolet Rays; D014983:Xeroderma Pigmentosum / Q000145:classification / Q000235:genetics*
chemical_list: D004247:DNA