Metabolic changes after application of kallikrein in an ergometrical test.
Kallikrein given in a dose of 3 times 200 KE daily over 7 days caused under our test conditions an increase of ATP in blood and a decrease of lactate and especially of pyruvate. Glucose showed under this condition a higher utilization with a lowering of glucose in blood and an increase of the RQ. The acid-base metabolism follows these tendencies. In other experiments we did not find such effects, so the results must be specific to kallikrein.
D000255:Adenosine Triphosphate / Q000097:blood; D001639:Bicarbonates / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D006801:Humans; D007610:Kallikreins; D007773:Lactates / Q000097:blood; D010100:Oxygen / Q000097:blood; D005082:Physical Exertion; D011773:Pyruvates / Q000097:blood
D001639:Bicarbonates; D001786:Blood Glucose; D007773:Lactates; D011773:Pyruvates; D000255:Adenosine Triphosphate; D007610:Kallikreins; D010100:Oxygen