title: A new approach to the study of lipid-protein interactions in the structure of biological membranes.
abstract: The lytic action of a number of N-acyl amino acids on lecithin liposomes was examined. The agents' affinity for lecithin liposome membrane was measured and the results obtained were treated to estimate the interactions of the amino acid residues with the lecithin polar head group at the surface of the liposome membrane. The data were considered in relation to the study of the surfactant effects on the erythrocyte volume. The ability of the suggested approach to obtain information on protein-lipid interactions inaccessible by other techniques is briefly commented on.
mesh_terms: D000596:Amino Acids; D055598:Chemical Phenomena; D002621:Chemistry; D007850:Lauric Acids; D008051:Lipid Bilayers; D008081:Liposomes; D010713:Phosphatidylcholines; D012995:Solubility; D013501:Surface-Active Agents
chemical_list: D000596:Amino Acids; D007850:Lauric Acids; D008051:Lipid Bilayers; D008081:Liposomes; D010713:Phosphatidylcholines; D013501:Surface-Active Agents