[Early changes of liver microsomal lipids in acute thiobenzamide poisoning].
The administration to rats of Thiobenzamide, a new liver toxin, induces the early appearance of conjugated dienes among microsomal lipids. Along with an increased malonic dialdehyde "in vitro", the finding suggests lipid peroxidation to occur.
D000818:Animals; D001549:Benzamides / Q000633:toxicity*; D050356:Lipid Metabolism; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D008862:Microsomes, Liver / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D013854:Thioamides; D013871:Thiones / Q000633:toxicity; D013997:Time Factors
D001549:Benzamides; D008054:Lipid Peroxides; D013854:Thioamides; D013871:Thiones; D008315:Malondialdehyde; C015539:thiobenzamide
Alterazioni precoci dei lipidi microsomiali del fegato in corso di intossicazione acuta con tiobenzamide.