Harderian gland dacryoadenitis in rats resulting from orbital bleeding.
Localized necrotizing inflammation of the Harderian gland was a sequela to obtaining blood samples from rats by the orbital bleeding technique. The lesion affected a few adjoining lobules that were adjacent to ocular muscles, in contrast to the widespread inflammation of the Harderian gland which results from sialodacryoadenitis virus infection. Lesions resolved in 4 weeks by atrophy of acini in affected lobules with associated mononuclear cell inflammation and fibrosis.
D000818:Animals; D001800:Blood Specimen Collection; D003607:Dacryocystitis / Q000209:etiology / Q000662:veterinary; D005260:Female; D006243:Harderian Gland / Q000473:pathology*; D007765:Lacrimal Apparatus / Q000473:pathology*; D009915:Orbit / Q000098:blood supply; D051381:Rats; D012376:Rodent Diseases / Q000209:etiology*