Pulmonary hypertension in silicotic rats.
In male rats, pulmonary hypertension was found 9, 17 to 18, and 30 wk after an intrapulmonary injection of 50 mg quartz dust suspended in saline. Pulmonary arterial blood pressure increased progressively with time, and in the oldest group, the weight of the right heart ventricle was increased.
D000818:Animals; D001794:Blood Pressure; D002245:Carbon Dioxide / Q000097:blood; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006976:Hypertension, Pulmonary / Q000150:complications*; D008297:Male; D010100:Oxygen / Q000097:blood; D011651:Pulmonary Artery / Q000503:physiopathology*; D051381:Rats; D012829:Silicosis / Q000097:blood / Q000150:complications / Q000503:physiopathology*
D006454:Hemoglobins; D002245:Carbon Dioxide; D010100:Oxygen