[Changes in the cholinosensitivity of sensomotor cortex neurons during conditioned reflex extinction].
Characteristics of neuronal responses of the sensorimotor cortex to ionophoretically administered neuromediators (acetylcholine, L-glutamate) were studied in rabbit in the course of extinction of conditioned defensive reflex. In the majority of neurones the extinction of the conditioned reflex is accompanied by a drop of cholinosensitivity. In a number of neurones the extinction of reflexes either does not change the reaction to acetylcholine, or enhances it. The analysis of these reactions permits to assume the existence of a group of neurones directly involved in the formation, fixation and storage of the temporary connection.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D003214:Conditioning, Classical / Q000502:physiology*; D004597:Electroshock; D005108:Extinction, Psychological / Q000502:physiology*; D005971:Glutamates / Q000494:pharmacology; D009044:Motor Cortex / Q000187:drug effects* / Q000502:physiology; D011817:Rabbits; D013003:Somatosensory Cortex / Q000187:drug effects* / Q000502:physiology; D013016:Sound
D005971:Glutamates; D000109:Acetylcholine
Izmenenie kholinochuvstvitel'nosti neĭronov sensomotornoĭ kory pri ugashenii uslovnogo refleksa.