title: Studies on the optimal dosage of co-trimazine in children.
abstract: There are many difficulties in creating a simple and useful dosage schedule for co-trimazine treatment in children. However, it has been possible to propose a schedule based on age. No advantage can be seen in choosing doses according to weight or other measures of body size. The schedule referred to as schedule B leads to levels of both sulphadiazine and trimethoprim that are as near the optimal as possible with respect to efficacy and side-effects.
mesh_terms: D000328:Adult; D000367:Age Factors; D001424:Bacterial Infections / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007223:Infant; D007700:Kinetics; D008297:Male; D013411:Sulfadiazine / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D014295:Trimethoprim / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D004338:Drug Combinations; D013411:Sulfadiazine; D014295:Trimethoprim