title: Interaction of alpha-actinin, filamin and tropomyosin with F-actin.
abstract: The abilities of alpha-actinin, filamin and tropomyosin to bind F-actin were examined by cosedimentation experiments. Results indicated that smooth muscle alpha-actinin and filamin can bind to actin filaments simultaneously with little evidence of competition. In contrast, tropomyosin exhibits marked competition with either filamin or alpha-actinin for sites on actin filaments.
mesh_terms: D000185:Actinin; D000199:Actins; D000818:Animals; D002352:Carrier Proteins; D002645:Chickens; D003285:Contractile Proteins; D005895:Gizzard, Avian / Q000032:analysis; D046911:Macromolecular Substances; D009124:Muscle Proteins; D009130:Muscle, Smooth / Q000032:analysis; D011485:Protein Binding; D014335:Tropomyosin; D014422:Turkeys
chemical_list: D000199:Actins; D002352:Carrier Proteins; D003285:Contractile Proteins; D046911:Macromolecular Substances; D009124:Muscle Proteins; D014335:Tropomyosin; D000185:Actinin