[Influence of bioflavonoid (4-methylesculetin) on the reaction of isolated calf hepatic artery to serotonin].
The effect of 4-metilesculetin on strips of calf hepatic arteries was investigated. 4-metilesculetin antagonizes the contraction induced by 5-HT probably through activation of the synthesis of vasodilator prostaglandins.
D000818:Animals; D002417:Cattle; D006499:Hepatic Artery / Q000187:drug effects*; D009119:Muscle Contraction / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology; D011453:Prostaglandins / Q000096:biosynthesis; D012603:Scopoletin / Q000494:pharmacology*; D012701:Serotonin / Q000494:pharmacology*; D012702:Serotonin Antagonists; D014468:Umbelliferones / Q000494:pharmacology*
D011453:Prostaglandins; D012702:Serotonin Antagonists; D014468:Umbelliferones; D012701:Serotonin; D012603:Scopoletin
Influenza di un bioflavonoide (4-metilesculetolo) sulle risposte di arterie epatiche isolate di vitello alla serotonina.