title: Iodine absorption from the gastrointestinal tract during hypaque-enema examination.
abstract: Iodinated contrast agents administered intravenously or intra-arterially may cause serious reactions in hypersensitive patients. Oral administration of Hypaque (diatrizoate sodium) results in minimal absorption of iodine, but the amount of iodine absorbed with Hypaque-enema studies is unreported. Hypaque-enema examinations were performed in 20 normal, nonsensitive patients and increased serum iodine levels ten to 200 times base-line values, peaking after approximately one hour in patients who had measurements obtained for four hours. Therefore, before Hypague-enema studies, patients must be carefully questioned about their tolerance of iodinated contrast agents, and preparations should be made for possible serious hypersensitivity reactions.
mesh_terms: D000328:Adult; D003106:Colon / Q000000981:diagnostic imaging / Q000378:metabolism; D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects*; D004064:Digestive System / Q000000981:diagnostic imaging* / Q000378:metabolism; D004733:Enema; D006801:Humans; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000000981:diagnostic imaging / Q000378:metabolism; D007455:Iodine / Q000378:metabolism*; D008875:Middle Aged; D011859:Radiography; D013997:Time Factors
chemical_list: D003287:Contrast Media; D007455:Iodine