title: [Polarographic determination of lipid hydroperoxides in the liver of guinea pigs on a varying allowance of ascorbic acid].
abstract: As shown by polarographic method, administration of high doses of ascorbic acid into guinea pigs (100 mg per 100 g of body weight) within two weeks led to a distinct increase (2-fold) in concentration of endogenous peroxides in liver tissue. Maintaining of the animals on a diet, deficient in vitamin C, within 4 weeks (scorbutic animals) was accompanied by 1.6-fold decrease in content of lipid peroxides in liver tissue as compared with control group.
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000008:administration & dosage*; D001206:Ascorbic Acid Deficiency / Q000378:metabolism; D004032:Diet; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D008054:Lipid Peroxides / Q000032:analysis*; D008099:Liver / Q000032:analysis*; D011048:Polarography / Q000379:methods*; D013997:Time Factors
chemical_list: D008054:Lipid Peroxides; D001205:Ascorbic Acid
vernacular_title: Poliarograficheskoe opredelenie gidroperekiseĭ lipidov v pecheni morskikh svinok pri razlichnoĭ obespechennosti askorbinovoĭ kislotoĭ.