Chromatid breaks induced in Chinese hamster cells by low doses (12--100 rad) of pi--mesons.
Monolayer cultures of the fibroblast-like Chinese hamster cell-line 19/1 were irradiated in the G2-phase of the cell cycle by pi--mesons (6 rad/min peak-pion dose rate). Frequencies of induced single- and isochromatid breaks, acentric fragments and interchanges were compared with data obtained from 140 kV X-rays. The RBE-values were for the pion dose peak between 0.8--1.2 and for the pion dose plateau 0.5--0.9. Whereas for single chromatid breaks there was no significant difference between X-rays and peak pions for identical physical doses, the isochromatid breaks alone showed a significantly higher frequency for 100 rad peak pions.
D000818:Animals; D002842:Chromatids / Q000528:radiation effects*; D006224:Cricetinae; D003412:Cricetulus; D004307:Dose-Response Relationship, Radiation; D004601:Elementary Particles; D066298:In Vitro Techniques; D014965:X-Rays