title: Poly-plethysmographic study on the effects of ritodrine on the cardiovascular system of patients in labour.
abstract: The effects of ritodrine infusion on the cardiovascular system of six women in threatened or premature labour are reported. In contrast to other betamimetics, ritodrine caused a moderate rise in systolic blood pressure, the corresponding fall in diastolic pressure leading to a widened pulse pressure but no risk of hypotension. Ritodrine caused a rise in cardiac output, and was well tolerated by the patients. Special care should be taken in treating patients with known heart disease.
mesh_terms: D000293:Adolescent; D000328:Adult; D001775:Blood Circulation / Q000187:drug effects*; D001794:Blood Pressure / Q000187:drug effects; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007743:Labor, Obstetric; D007752:Obstetric Labor, Premature / Q000503:physiopathology*; D010701:Phonocardiography; D010991:Plethysmography; D011247:Pregnancy; D011412:Propanolamines / Q000494:pharmacology*; D012312:Ritodrine / Q000494:pharmacology*
chemical_list: D011412:Propanolamines; D012312:Ritodrine