[Preoperative administration of antacids to prevent Mendelson's syndrome in pregnant women receiving general anesthesia (author's transl)].
Preoperative administration of 15 mls of the antacid Andursil to women undergoing surgical procedures in GA during pregnancy does reduce the risk of aspiration pneumonitis (Mendelson-Syndrome) from 1:3,5 to 1:15,5. The data show that the number of risk patients is increased in early stages of pregnancy and--surprisingly--in patients undergoing elective surgery. Pains and costs of prophylactic antacids are negligible. Neonates of LSCS patients receiving an antacid are not at an increased risk. As a conclusion the prophylactic administration of oral antacids to all pregnant women having a GA is recommended.
D000768:Anesthesia, General; D000863:Antacids / Q000627:therapeutic use*; D002585:Cesarean Section; D005260:Female; D006801:Humans; D011015:Pneumonia, Aspiration / Q000517:prevention & control*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000601:surgery*; D013577:Syndrome; D013997:Time Factors
D000863:Antacids
Antazida zur Verhütung des Mendelson-Syndroms bei operativen Eingriffen in Allgemeinnarkose während der Schwangerschaft.