The effects of temporary fluid restriction in clip-nephrectomized rats.
Constriction of the remaining renal artery in unilaterally nephrectomized rats is associated with a high mortality in the early post-operative phase before hypertension has developed. The high mortality is accompanied by increased vascular permeability, mesenteric and pancreatic oedema. Temporary post-operative water restriction reduces this mortality and also modifies subsequent blood pressure elevation, heart weight and cardiac index in surviving animals.
D000818:Animals; D002199:Capillary Permeability; D003250:Constriction; D005260:Female; D006977:Hypertension, Renal / Q000378:metabolism* / Q000473:pathology; D009392:Nephrectomy; D051381:Rats; D012077:Renal Artery / Q000502:physiology*; D014867:Water / Q000378:metabolism*; D014882:Water-Electrolyte Balance
D014867:Water