Treatment of a neonate with propionic acidaemia and severe hyperammonaemia by peritoneal dialysis.
A moribund newborn infant with propionic acidaemia and severe hyperammonaemia was successfully treated by peritoneal dialysis. The removal of ammonia and possibly additional toxic metabolites by peritoneal dialysis may be life-saving in newborn infants with propionic acidaemia or other hyperammonaemic syndromes.
D000592:Amino Acid Metabolism, Inborn Errors / Q000201:enzymology / Q000628:therapy*; D000641:Ammonia / Q000097:blood*; D002262:Carboxy-Lyases / Q000172:deficiency; D003437:Crotonates; D005260:Female; D005347:Fibroblasts / Q000201:enzymology; D006801:Humans; D007231:Infant, Newborn; D007962:Leukocytes / Q000201:enzymology; D008025:Ligases / Q000172:deficiency; D010530:Peritoneal Dialysis; D011422:Propionates / Q000097:blood*
D003437:Crotonates; D011422:Propionates; D000641:Ammonia; D002262:Carboxy-Lyases; D008025:Ligases