Effect of orchidectomy and estradiol on acetylcholinesterase activity in rat brain areas and adenohypophysis.
Orchidectomy plus estradiol administration decreased acetylcholinesterase activity in the rat cerebral cortex and mesencephalon, while in the amygdala it was increased. In the adenohypophysis, orchidectomy increased enzyme activity, but subsequent estradiol treatment decreased it. The hypothalamus did not respond to either manipulation.
D000110:Acetylcholinesterase / Q000378:metabolism*; D000679:Amygdala / Q000201:enzymology; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology*; D002369:Castration; D002540:Cerebral Cortex / Q000201:enzymology; D004958:Estradiol / Q000494:pharmacology*; D007031:Hypothalamus / Q000201:enzymology; D008297:Male; D008636:Mesencephalon / Q000201:enzymology; D009928:Organ Specificity; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000201:enzymology*; D051381:Rats
D004958:Estradiol; D000110:Acetylcholinesterase