title: Lamellar bodies at the cell periphery of human muscle fibers.
abstract: The cytochemical and ultrastructural features of lamellar bodies in human skeletal muscle fibers were studied using tannic acid-glutaraldehyde, ruthenium red-glutaraldehyde fixation methods, conventional electron microscopy and the freeze fracture technique. The lamellar bodies consisted of concentric lamellae with a regular spacing of 6.5 +/- 0.2 nm. These structures were found preferentially at the cell periphery closely associated with the plasma membrane, near the nuclear poles and in the space between muscle fiber and satellite cell. The cytochemical and ultrastructural features of the lamellar bodies suggest they are largely composed of phospholipid. It is possible that these structures are involved in muscle membrane maintenance.
mesh_terms: D000328:Adult; D002462:Cell Membrane / Q000648:ultrastructure; D002648:Child; D005260:Female; D005614:Freeze Fracturing; D006801:Humans; D047348:Hydrolyzable Tannins; D008297:Male; D008854:Microscopy, Electron; D009132:Muscles / Q000648:ultrastructure*; D009685:Nuclear Envelope / Q000648:ultrastructure; D009940:Organoids / Q000648:ultrastructure; D010743:Phospholipids / Q000032:analysis; D012430:Ruthenium Red
chemical_list: D047348:Hydrolyzable Tannins; D010743:Phospholipids; D012430:Ruthenium Red