The relationship between fibrinogen degradation products and cryofibrinogen.
Cryofibrinogen obtained from four children with inflammatory diseases was invesitgated for immunoglobulin and FDP activity. It is concluded that the potential for fibrinogenolysis is present in cryofibrinogen but it is not necessary for its formation. The proteins in the cryoprecipitates that migrate electrophorectically with the alpha-, beta- and gamma-globulins represent immunoglobulins and, perhaps, some FDP.
D001797:Blood Protein Electrophoresis; D011232:Chemical Precipitation; D002648:Child; D003080:Cold Temperature; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism*; D005340:Fibrinogen / Q000378:metabolism*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis
D005338:Fibrin Fibrinogen Degradation Products; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D005340:Fibrinogen