title: Ovine coccidiosis: comparison of the effects of monensin and aureomycin on lambs infected with coccidia.
abstract: Lambs naturally infected with mixed species of Eimeria were fed monensin (30 mg/kg of feed) and aureomycin (10 mg/kg of feed) separately and in combination. An evaluation was made of the efficacy of the treatments in the suppression of oocyst production. Comparisons were made of the parasitic damage to the intestinal surface. Performance of the lambs was measured by weight gains and feed efficiency. Monensin given separately or in combination with aureomycin produced decreases in oocyst counts that were not significantly different from those in the lambs given only aureomycin. Body weight gains and feed efficiency were best in the aureomycin-treated group, and less so in the monensin-treated and the control groups. Animals fed the monensin-aureomycin combination had the poorest weight gains and feed efficiency. Scanning electron microscopy indicated that the groups fed monensin or aureomycin separately had morphologically normal intestinal surfaces. This was in contrast to the control group and the group fed the monensin-aureomycin combination, wherein there was disrupted intestinal surface morphology.
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002751:Chlortetracycline / Q000008:administration & dosage / Q000627:therapeutic use*; D003048:Coccidiosis / Q000188:drug therapy / Q000662:veterinary*; D003049:Coccidiostats / Q000008:administration & dosage / Q000627:therapeutic use; D004338:Drug Combinations; D005663:Furans / Q000627:therapeutic use*; D008985:Monensin / Q000008:administration & dosage / Q000627:therapeutic use*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy*
chemical_list: D003049:Coccidiostats; D004338:Drug Combinations; D005663:Furans; D008985:Monensin; D002751:Chlortetracycline