title: [Use of a 1:1 association of ampicillin and flucloxacillin in surgical patients (author's transl)].
abstract: This clinical trial was designed to assess the validity of an association of equal parts of ampicillin and flucloxacillin in surgical patients; the product was administered by injection in daily doses of 2-3 grams. In a group of 20 patients the same product was used prophylactically against infection, with positive results in 85% of the cases; the mean duration of treatment was 5 days. In 13 patients affected by urinary and biliary infections the product was effective. After a 7 days-therapy, 11 cases showed a marked improvement of the clinical symptomatology. Allergic cutaneous reactions (rashes, itching) appeared in five cases. No other side-effects had been noticed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000667:Ampicillin / Q000008:administration & dosage* / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy / Q000517:prevention & control*; D003023:Cloxacillin / Q000031:analogs & derivatives*; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D005436:Floxacillin / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D013514:Surgical Procedures, Operative
chemical_list: D004338:Drug Combinations; D005436:Floxacillin; D000667:Ampicillin; D003023:Cloxacillin
vernacular_title: L'associazione ampicillina-flucloxacillina 1:1 nel paziente chirurgico.