Acetazolamide in the treatment of haemorrhagic glaucoma.
For the first time the clinical effect of acetazolamide (AZA) in haemorrhagic glaucoma has been the subject of a controlled study. The clinical impression of none, or a slight effect of AZA in haemorrhagic glaucoma was confirmed. An intravenous injection of a AZA, 10 mg/kg body weight, produced in 13 patients (14 eyes) with haemorrhagic glaucoma a fall in the intraocular pressure (IOP) of only 7.7% within 30 min. A similar examination of 4 patients (5 eyes) with other types of glaucoma showed a drop in pressure of 32.0%. Examinations of the haemorrhagic-glaucoma eyes later that day and on the next day showed no further effect of AZA on the IOP. It is concluded that AZA is of no importance in the treatmen of haemorrhagic glaucoma.
D000086:Acetazolamide / Q000627:therapeutic use*; D000368:Aged; D005260:Female; D005901:Glaucoma / Q000188:drug therapy*; D006470:Hemorrhage / Q000188:drug therapy; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D000086:Acetazolamide