Raynaud's phenomenon in hypertensive dialysis patients taking a sustained-release propranolol formulation.
Five dialysis patients with residual hypertension were treated with a new sustained-release formulation of propranolol (160 mg per capsule) in a dosage of 1 to 2 capsules per day. Four of these patients developed persistent cold, numb, blue and clumsy fingers. The symptoms resolved when the drug was withdrawn.
D003692:Delayed-Action Preparations; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011433:Propranolol / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D011928:Raynaud Disease / Q000139:chemically induced*; D006435:Renal Dialysis
D003692:Delayed-Action Preparations; D011433:Propranolol