title: Elimination and metabolism of dimethylnitrosamine (DMN) by Xenopus laevis and other amphibians.
abstract: The elimination of (14C)-DMN after i.p. injection into Xenopus was measured, as was the metabolism in vitro of (14C)-DMN by liver from Xenopus and 9 other amphibian species. In view of its rapid elimination from the body and low rate of metabolism by Xenopus liver in vitro, DMN is unlikely to be toxic or carcinogenic in Xenopus.
mesh_terms: D000663:Amphibians; D000818:Animals; D002250:Carbon Radioisotopes; D004128:Dimethylnitrosamine / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D051381:Rats; D013045:Species Specificity; D014981:Xenopus / Q000378:metabolism*
chemical_list: D002250:Carbon Radioisotopes; D004128:Dimethylnitrosamine