title: [Neomycin resorption from the normal and inflammatorily altered peritoneum].
abstract: The clinical problem of the resorption of Neomycin from the normal and inflammatory altered peritoneal cavity was studied experimentally in the guinea pig. In a total of 197 guinea pigs the pharmacokinetics of Neomycin in serum and perilymph after injection subcutaneously or in normal and inflammatorily altered peritoneal cavity of the guinea pig were determined. No statistically significant difference between the pharmacokinetics of Neomycin in serum and perilymph of the different series could be found. The possible clinical relevance of the results is discussed.
mesh_terms: D000042:Absorption; D000818:Animals; D006168:Guinea Pigs; D034381:Hearing Loss; D009355:Neomycin / Q000009:adverse effects / Q000097:blood / Q000378:metabolism*; D010498:Perilymph / Q000032:analysis; D010537:Peritoneum / Q000502:physiology*; D010538:Peritonitis / Q000503:physiopathology*
chemical_list: D009355:Neomycin
vernacular_title: Zur Neomycin-Resorption aus dem gesunden und entzündlich veränderten Peritoneum.