Activation of AMP aminohydrolase during skeletal-muscle contraction.
AMP aminohydrolase activity is enhanced by 60% after 5 s tetanic stimulation of phosphorylase kinase-deficient mouse muscle and after 60 s tetanus in normal mice. During the recovery from tetanus the activity in the contralateral leg is similarly enhanced. The activation is stable to 1000-fold dilution and has a half-life of approx. 1 h.
D000659:AMP Deaminase / Q000378:metabolism*; D000818:Animals; D004789:Enzyme Activation; D051379:Mice; D009119:Muscle Contraction; D009132:Muscles / Q000201:enzymology*; D009709:Nucleotide Deaminases / Q000378:metabolism*; D010764:Phosphorylase Kinase / Q000172:deficiency
D010764:Phosphorylase Kinase; D009709:Nucleotide Deaminases; D000659:AMP Deaminase