Mediastinal embryonal carcinoma with bilateral choroidal metastases. Fluorescein angiographic and histopathologic study.
28-year-old sportsman developed chest pain, dyspnoea, haemoptysis and swelling of the right leg. 8 weeks later he also complained of blurred vision. Ophthalmoscopy revealed subretinal infiltrates diagnosed as tumour metastases by fluorescein angiography. The patient died 10 weeks after the first symptoms. At autopsy large mediastinal embryonal carcinoma was diagnosed, and both eyes revealed choroidal metastases. This rare tumour usually involves young men and is invariably fatal within a few months. Exceptional bilateral choroidal metastases constituted the presenting sign.
D000328:Adult; D002830:Choroid Neoplasms / Q000473:pathology / Q000556:secondary*; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology*; D009362:Neoplasm Metastasis; D013724:Teratoma / Q000473:pathology / Q000556:secondary*