Increased incidence of lymphomas in survivors of the host-versus-graft syndrome.
When (SB)F1 spleen cells were injected into perinatal parental B strain mice a lethal runting syndrome was induced. The survivors showed a significantly increased incidence of lymphomas in old age. The tumors occurred much later and less frequently than in the reverse reaction, B leads to (SB)F1 GVHD.
D000818:Animals; D006789:Host vs Graft Reaction; D008223:Lymphoma / Q000276:immunology*; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000276:immunology; D013154:Spleen / Q000637:transplantation*; D014184:Transplantation, Homologous