title: Poliomyelitis, rubella, and dengue antibody survey in Barbados. A follow-up study.
abstract: A follow-up study of poliomyelitis, rubella, and dengue antibodies has been made in light of results obtained in a 1972 health and serological survey in Barbados, W.I. Poliomyelitis antibody neutralization tests performed on sera from 307 children under age 15 using overnight serum/virus mixtures on microtiter plates at low serum dilutions revealed the absence of polio antibody at 1:2 dilution in 13.7% for type 1, 6.5% for type 2, and 14.3% for type 3 virus. A significant correlation of the presence or absence of poliomyelitis antibody to types 2 and 3 was seen with the response to immunization histories. Forty-three of 49 girls (88%) given rubella vaccine (RA 27/3) in 1972 had demonstrable haemagglutination-inhibition antibody 4 years later. Neutralization tests for dengue antibody confirmed the results of the complement-fixation tests and indicated that type 2 was probably the sole infecting strain.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000914:Antibodies, Viral / Q000032:analysis*; D001460:Barbados; D002648:Child; D002675:Child, Preschool; D003168:Complement Fixation Tests; D003715:Dengue / Q000276:immunology*; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007114:Immunization; D007223:Infant; D008297:Male; D009500:Neutralization Tests; D011051:Poliomyelitis / Q000276:immunology*; D012409:Rubella / Q000276:immunology*; D012737:Sex Factors
chemical_list: D000914:Antibodies, Viral