title: Regional differences in high-affinity choline uptake in brain after acute and chronic treatment with ethanol.
abstract: A single  dose of ethanol has been shown to affect both striatal and hippocampal high-affinity choline uptake. This effect is probably mediated through effects of ethanol on acetylcholine release. Choline uptake has also been shown to be altered in ethanol-dependent animals, and these effects may be coupled to alterations in dopamine neurons which are produced by chronic ethanol feeding and withdrawal.
mesh_terms: D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D002794:Choline / Q000378:metabolism*; D003342:Corpus Striatum / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000008:administration & dosage / Q000494:pharmacology*; D006624:Hippocampus / Q000378:metabolism*; D008297:Male; D051381:Rats
chemical_list: D000431:Ethanol; D002794:Choline; D000109:Acetylcholine