Linking of N4-aminocytosine to glutathione by use of bromopyruvate.
N4-Aminocytosine reacted with acetone and acetaldehyde to form hydrazones that were readily revertible to the parent compound. With pyruvate, in contrast, it formed a stable hydrazone. By use of bromopyruvate, N4-aminocytosine was linked to glutathione.
D002625:Chemistry, Organic; D003596:Cytosine / Q000031:analogs & derivatives*; D005978:Glutathione; D006835:Hydrazones; D008722:Methods; D055601:Organic Chemistry Phenomena; D011773:Pyruvates
D006835:Hydrazones; D011773:Pyruvates; C025320:N(4)-aminocytosine; C017092:bromopyruvate; D003596:Cytosine; D005978:Glutathione