title: Effect of glycerol on carotenogenesis in the extreme halophile, Halobacterium cutirubrum.
abstract: Growth of cells of Halobacterium cutirubrum in complex medium in the presence of 0.1 to 0.5% glycerol was slightly stimulated (about 10%), but the content of the major red pigment, bacterioruberin, was reduced fourfold and that of the minor red pigments, mono- and bisanhydrobacterioruberins, was also reduced but to a lesser extent. The content of the C40 carotenes, beta-carotene and lycopene, however, was greatly increased in 0.1 to 0.5% glycerol but was then reduced to negligible amounts at higher glycerol concentrations (1 to 5%). Similar effects of glycerol on carotenogenesis were observed when cells were grown in a chemically defined medium (BSMK), but growth of cells was considerably slower.
mesh_terms: D002338:Carotenoids / Q000096:biosynthesis*; D003470:Culture Media; D005990:Glycerol / Q000494:pharmacology*; D006217:Halobacterium / Q000187:drug effects* / Q000378:metabolism; D008055:Lipids / Q000096:biosynthesis; D013185:Squalene / Q000096:biosynthesis; D014812:Vitamin K / Q000031:analogs & derivatives / Q000096:biosynthesis; D024482:Vitamin K 2 / Q000031:analogs & derivatives*; D014815:Vitamins / Q000096:biosynthesis
chemical_list: D003470:Culture Media; D008055:Lipids; D014815:Vitamins; D024482:Vitamin K 2; D014812:Vitamin K; C002951:bacterioruberin; D002338:Carotenoids; C024223:vitamin MK 8; D013185:Squalene; D005990:Glycerol