title: [Respiration at high altitudes, phosphate-protein interaction: the sequence of hemoglobins from guinea pig and dromedary (author's transl)].
abstract: The sequence of the main hemoglobin component of the guinea pig (Cavia aerea f. porcellus, Caviidae) and that of the hemoglobin of the dromedary (Camelus dromedarius, Camelidae) is given. The sequence is obtained automatically by the sequenator using the quadrol and the propyne programme. The sequence of the alpha-and beta-chains of the guinea pig is compared with that of the human hemoglobin; the sequence of the dromedary in comparison to the Ilama shows in the alpha-chains five amino acid exchanges, in the beta-chains there are only two exchanges in beta 2 and beta 76. Beta 2 in dromedary is the P2-glycerate contact histidine. This sustains the interpretation of the high altitude respiration of the Ilama as mutation beta2His leads to Asn.
mesh_terms: D000531:Altitude; D000595:Amino Acid Sequence; D000818:Animals; D002161:Camelids, New World / Q000097:blood; D002162:Camelus / Q000097:blood*; D006168:Guinea Pigs / Q000097:blood*; D006454:Hemoglobins; D006801:Humans; D012119:Respiration; D013045:Species Specificity
chemical_list: D006454:Hemoglobins
vernacular_title: Höhenatmung, Phosphat-Protein-Wechselwirkung: Die Sequenz der Hämoglobine des Meerschweinchens und des Dromedars.