title: Ultrastructural localization of lactic dehydrogenase in mouse mammary carcinoma cells.
abstract: Electron microscopic study of lactic dehydrogenase (LDH) was carried out in C3H mouse mammary carcinoma cells. Scattered cytoplasmic LDH granules were noted as well as around mitochondria and nuclear membrane. Control studies with normal breast tissues failed to show any activity. This observation suggests that LDH plays an important role in C3H mammary carcinoma and may be of use as an additional marker.
mesh_terms: D000818:Animals; D002277:Carcinoma / Q000201:enzymology*; D005260:Female; D006651:Histocytochemistry; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008325:Mammary Neoplasms, Experimental / Q000201:enzymology* / Q000648:ultrastructure; D051379:Mice; D008809:Mice, Inbred C3H; D009374:Neoplasms, Experimental
chemical_list: D007770:L-Lactate Dehydrogenase