title: Maximal work capacity of women during acute hypoxia.
abstract: Six healthy women (22--34 yr of age) performed maximal bicycle work in a hypobaric chamber at sea level and at simulated altitudes of 2,130 and 3,050 m (barometric pressures, 758, 586, and 523 Torr). Maximal oxygen uptake (VO2max) decreased 10 and 15% from sea-level values at 2,130 and 3,050 m, respectively. At these altitudes minute ventilation (VEBTPS) increased 17 and 22% respectively, a consequence of increased respiratory rate (fR). Respiratory exchange ratios increased 10 and 14%, and oxygen pulse decreased 9 and 12%, respectively, at 2,130 and 3,050 m. Maximal blood lactates, heart rates, cardiac outputs, and plasma volume shifts were unaffected by these altitudes. Although during maximal work the percentage increases in VEBTPS, fR, and R that resulted from altitude exposure were greater in women than those previously reported for men, the decrements in VO2max were comparable to those in men. The results show that relative to their performance at sea level, men and women have equal ability to perform maximal work at altitudes up to 3,050 m.
mesh_terms: D000208:Acute Disease; D000328:Adult; D001274:Atmospheric Pressure; D002302:Cardiac Output; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000503:physiopathology*; D007773:Lactates / Q000378:metabolism; D008297:Male; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption; D005082:Physical Exertion; D010953:Plasma Volume; D012119:Respiration; D012737:Sex Factors
chemical_list: D007773:Lactates; D010100:Oxygen