title: Experimental study of cardiomyopathy induced by glucocorticoids.
abstract: Abnormal ECG changes were found in some patients who were treated glucocorticoid during long term. In experimental animals, chronic administration of glucocorticoid resulted abnormal ST and T changes of ECG, increased duration of action potential and induced electron microscopical changes of mitochondria. No significant changes were found in serum and myocardial potassium content.
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D009202:Cardiomyopathies / Q000139:chemically induced* / Q000473:pathology; D004285:Dogs; D004562:Electrocardiography; D005938:Glucocorticoids / Q000009:adverse effects*; D006439:Hemodynamics; D008928:Mitochondria / Q000648:ultrastructure; D009206:Myocardium / Q000648:ultrastructure; D011188:Potassium / Q000494:pharmacology; D011817:Rabbits; D051381:Rats
chemical_list: D005938:Glucocorticoids; D011188:Potassium