Determination of nikethamide and N-ethylnicotinamide in the blood and urine of greyhounds.
Following the intramuscular administration of nikethamide to a series of greyhounds, both plasma and urine excretion levels were obtained. A qualitative urine screening procedure for both nikethamide and its major metabolite has been devised. The method involves solvent extraction, thin-layer and a two-system gas chromatographic system.
D000818:Animals; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D003640:Dealkylation; D004285:Dogs / Q000097:blood / Q000378:metabolism* / Q000652:urine; D004300:Doping in Sports; D008401:Gas Chromatography-Mass Spectrometry; D008297:Male; D009552:Nikethamide / Q000097:blood / Q000378:metabolism* / Q000652:urine
D009552:Nikethamide