Capillary column gas chromatographic profile analysis of volatile compounds in sera of normal and virus-infected patients.
Using a transevaporator sampling technique, the volatile profiles from 70 microliter of serum were obtained by capillary-column gas chromatography. The complex chromatograms were interpreted by a combination of manual and computer techniques and a two-peak ratio method devised for the classification of normal and virus-infected sera. Using the K-nearest neighbor approach 85.7% of the unknown samples were classified correctly. Some preliminary results indicate the possible use of the method for the assessment of virus susceptibility.
D002849:Chromatography, Gas / Q000379:methods; D003201:Computers; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D007251:Influenza, Human / Q000097:blood*