title: [Dynamics of erythrocyte hexokinase activity during glucose tolerance test in children with hereditary diabetes mellitus].
abstract: In determining the changes in hexokinase activity in erythrocytes during the glucose tolerance test in children with heredity aggravated by diabetes mellitus in comparison with such in apparently healthy children it was shown that in latent diabets the enzyme activity failed to alter during the whold period of study (on fasting stomach, 30, 60 and 180 minutes after glucose load), and increased 60 minutes after glucose load in potential diabetes, but to a lesser extent than in the control group. Changes of erythrocyte hexokinase response to glucose administration could serve as an auxiliary criterion for determination of the degree of risk in children with threatening diabetes.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003920:Diabetes Mellitus / Q000235:genetics*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000175:diagnosis; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005951:Glucose Tolerance Test; D006593:Hexokinase / Q000097:blood*; D006801:Humans; D008297:Male
chemical_list: D006593:Hexokinase
vernacular_title: Dinamika aktivnosti geksokinazy v éritrotsitakh pri provedenii gliukozotolerantnogo testa u deteĭ s otiagoshchennoĭ po sakharnomu diabetu nasledstvennost'iu.