113mIn-tripolyphosphate: a new radiopharmaceutical for bone scanning.
A compound was synthetized, which by X-Ray diffraction studies proved to be hexahydrated sodium tripolyphosphate. By means of in vitro procedures, it was demonstrated that this compound was able to complex trivalent cations, and that 113mIn could be completely incorporated to it. In vivo studies in rats, and scans performed with this new radiopharmaceutical in humans showed its highly selective accumulation in metastasic bone tumors.
D000818:Animals; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D006801:Humans; D007204:Indium; D011122:Polyphosphates / Q000378:metabolism; D011868:Radioisotopes; D011877:Radionuclide Imaging; D051381:Rats; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging; D014018:Tissue Distribution
D011122:Polyphosphates; D011868:Radioisotopes; D007204:Indium