Morphological irregularities in Dane particle cores.
Electron microscopy of hepatitis B antigen has revealed Dane particles with abnormal morphology. These aberrant Dane particles contain incomplete cores. They were seen in large numbers in the serum of an HBsAg-carrying renal dialysis patient and were less numerous but invariably present in other Dane particle-containing sera --12 from asymptomatic carriers, 2 chronic hepatitis patients and 1 patient with acute hepatitis. All 16 sera were shown to contain HBeAg.
D000937:Antigen-Antibody Reactions; D002353:Carrier State / Q000276:immunology*; D006509:Hepatitis B / Q000276:immunology*; D006511:Hepatitis B Antigens / Q000032:analysis*; D006801:Humans; D008854:Microscopy, Electron; D006435:Renal Dialysis
D006511:Hepatitis B Antigens