The influence of extended glucagon infusion on liver cell regeneration after partial hepatectomy in the rat.
Extended infusion of various amounts of glucagon leads, in normal rats, to a slight reduction in liver cell DNA synthesis. After partial hepatectomy the extended infusion of glucagon causes a large reduction in DNA synthesis in the remaining liver.
D000818:Animals; D004247:DNA / Q000096:biosynthesis; D005260:Female; D005934:Glucagon / Q000494:pharmacology*; D006498:Hepatectomy; D007263:Infusions, Parenteral; D008115:Liver Regeneration / Q000187:drug effects*; D051381:Rats
D004247:DNA; D005934:Glucagon