title: The influence of exercise on muscle lysosomal enzymes.
abstract: Representative lysosomal enzyme activities were measured in muscles taken 0 h and 24 h after an acute exercise run that was completed without any overt signs of fatigue. The animals had progressed 2 and 4 weeks into a standard exercise program which typically produces adaptive changes in the working muscles. There was an increase in acetylglucosaminidase activity (12%) in the fast-twitch red muscle section of all animals that participated in the training program. This small increase may be representative of a delayed response found after more exhausting exercise. The single exercise bout, however, did not cause any acute change in lysosomal activity nor alter the partition of lysosomal enzymes between the "free" and particulate fractions. Thus, altered lysosomal enzyme activity does not appear to be a contributing influence that challenges muscle fiber homeostasis during moderately intense running.
mesh_terms: D000118:Acetylglucosaminidase / Q000378:metabolism; D000818:Animals; D002403:Cathepsins / Q000378:metabolism; D006706:Homeostasis; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D009132:Muscles / Q000201:enzymology*; D005082:Physical Exertion; D051381:Rats
chemical_list: D000118:Acetylglucosaminidase; D002403:Cathepsins