title: Gas-liquid chromatography of digitoxigenin and digoxigenin as acetates of their epoxygeninic acid methyl esters.
abstract: Gas chromatographic analysis of ditigoxigenin and digoxigenin, the genins of the cardenolide glycosides digitoxin and digoxin, cannot be done without derivatization. However, during the derivatization, side-reactions often present serious problems. A procedure has been found for transforming digitoxigenin and digoxigenin into the corresponding acetates of their epoxygeninic acid methyl esters, which are stable compounds and suitable for gas chromatographic analysis.
mesh_terms: D000085:Acetates / Q000032:analysis; D002849:Chromatography, Gas; D004073:Digitoxigenin / Q000032:analysis*; D004076:Digoxigenin / Q000032:analysis*; D004077:Digoxin / Q000031:analogs & derivatives*; D004355:Drug Stability; D004852:Epoxy Compounds / Q000032:analysis; D004952:Esters / Q000032:analysis
chemical_list: D000085:Acetates; D004852:Epoxy Compounds; D004952:Esters; D004073:Digitoxigenin; D004077:Digoxin; D004076:Digoxigenin