Failure to identify 'thrombocytolysin' (a spasmogenic factor released from platelets immunoreaction) with anaphylatoxin.
Horse platelets release an unidentified smooth muscle contracting substance after lysis by antiserum and complement. Since the active factor (thrombocytolysin) does not produce tachyphylactic response of the guinea-pig ileum it seems that it is not related to anaphylatoxins.
D000706:Anaphylatoxins; D000818:Animals; D001681:Biological Assay; D001792:Blood Platelets / Q000032:analysis*; D003165:Complement System Proteins; D006168:Guinea Pigs; D006736:Horses; D007082:Ileum / Q000187:drug effects; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010455:Peptides
D000706:Anaphylatoxins; D010455:Peptides; D003165:Complement System Proteins