title: The structural and infected cell polypeptides of influenza B virus.
abstract: Structural and virus-induced infected cell polypeptides of several strains of influenza B virus were examined by high resolution polyacrylamide gel electrophoresis and shown to be directly analogous to those of the influenza A viruses. Eight structural polypeptides, P1, P2, P3, HA1, HA2, NA, NP and M were observed in purified virus and at least two additional polypeptides, HA and NS could be detected in infected MDCK cells. The three P proteins  plus NP were shown to be associated with RNA-dependent RNA polymerase activity and HA, HA1, HA2 and NA were shown to be glycosylated. Like the influenza A viruses, migrational differences of some of the infected cell polypeptides could be observed between different B strains. Investigation of a time course of virus replication failed to show any temporal control of protein synthesis in the infected cell.
mesh_terms: D000818:Animals; D002460:Cell Line; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D004285:Dogs; D006023:Glycoproteins / Q000032:analysis; D007668:Kidney; D008970:Molecular Weight; D009975:Orthomyxoviridae / Q000032:analysis* / Q000201:enzymology / Q000254:growth & development; D010455:Peptides / Q000032:analysis*; D014779:Virus Replication
chemical_list: D006023:Glycoproteins; D010455:Peptides; D012321:DNA-Directed RNA Polymerases