[Serological classification of post-transfusion hepatitis (author's transl)].
Post-transfusion hepatitis (PTH) remains to be a major hazard after massive blood transfusions. After 141 cardiac surgeries with massive blood transfusions the frequency of PTH reached 38%. The natural history of this type of hepatitis proved to be clinically mild but usually protracted. Icterus was found in one third. Serologically 46% of the PTH could be identified by HBs-Ag-testing as type B hepatitis. 39% revealed anti-HBs and 15% remained unclassified. HBs-Ag or anti-HBs were found in 40% patients without clinical or biochemical evidences of a hepatitis. The diagnosis of PTH still should rely on a synopsis of a typical clinical and biochemical hepatitis syndrome, characteristic serological findings and an adequate intervall between blood transfusion and outbreak of hepatitis.
D000328:Adult; D001021:Aortic Valve; D002648:Child; D005260:Female; D006350:Heart Valve Prosthesis; D006505:Hepatitis / Q000145:classification* / Q000209:etiology; D006509:Hepatitis B / Q000145:classification; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D007565:Jaundice / Q000209:etiology; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D065227:Transfusion Reaction
D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens
Die serologische Klassifizierung der Posttransfusionshepatitis.