title: Immunological tolerance and dogma.
abstract: Immunization and tolerance induction are complementary rather than antagonistic aspects of immune responsiveness. Adult normal organisms may become tolerant to proteins ingested as food. This has been known for a long time but has failed to influence immunological thinking. It is argued that the notion of oral tolerance is incompatible with current immunological paradigms and demand their revision.
mesh_terms: D000818:Animals; D000917:Antibody Formation; D006801:Humans; D007108:Immune Tolerance; D007111:Immunity, Cellular; D008214:Lymphocytes / Q000276:immunology; D011506:Proteins / Q000276:immunology*; D011971:Receptors, Immunologic
chemical_list: D011506:Proteins; D011971:Receptors, Immunologic