Coarctation in children. Controlled hypotension using labetalol and halothane.
Hypotension was induced with halothane and labetalol, an alpha and beta adrenergic blocking agent, in nine children undergoing operation for postductal coarctation of the aorta. The mean arterial pressure decreased by an average of 30% following labetalol, and in six patients the initial halothane concentration (1%) had to be reduced during this period. The heart rate decreased by an average of 8% after labetalol. Profound beta-blockade did not occur, and operating conditions were considered satisfactory. The usefulness of labetalol in the postoperative period is suggested.
D000293:Adolescent; D001017:Aortic Coarctation / Q000601:surgery*; D001794:Blood Pressure; D002648:Child; D002675:Child, Preschool; D004983:Ethanolamines; D006221:Halothane; D006339:Heart Rate; D006801:Humans; D007023:Hypotension, Controlled / Q000379:methods*; D007223:Infant; D007741:Labetalol
D004983:Ethanolamines; D007741:Labetalol; D006221:Halothane