title: Effect of premedication on etomidate anaesthesia.
abstract: The effect of premedication upon the induction of anaesthesia with etomidate was studied in 74 adult patients undergoing elective orthopaedic surgery. Premedication with fentanyl plus atropine or with diazepam plus atropine decreased the frequency of involuntary muscle movements without modifying the pattern of the circulatory effects of etomidate, although fentanyl increased the frequency of apnoea. Pain at the site of injection was not modified by premedication.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous / Q000009:adverse effects; D001285:Atropine; D003975:Diazepam; D005045:Etomidate / Q000009:adverse effects; D005283:Fentanyl; D006801:Humans; D007093:Imidazoles / Q000009:adverse effects; D008875:Middle Aged; D010146:Pain / Q000139:chemically induced / Q000517:prevention & control; D011229:Preanesthetic Medication
chemical_list: D007093:Imidazoles; D001285:Atropine; D003975:Diazepam; D005283:Fentanyl; D005045:Etomidate