5-Methylangelicin: a new highly photosensitizing angular furocoumarin.
5-Methylangelicin, a new highly photosensitizing angular furocoumarin, was studied in 2 different biological systems, the T2 phage and Ehrlich ascites tumor cells; in comparison with angelicin, the parent compound, it was several times more active.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000503:physiopathology*; D002470:Cell Survival / Q000187:drug effects / Q000528:radiation effects; D004273:DNA, Neoplasm / Q000096:biosynthesis; D011564:Furocoumarins / Q000494:pharmacology*; D051379:Mice; D012334:RNA, Neoplasm / Q000096:biosynthesis; D013329:Structure-Activity Relationship; D013604:T-Phages / Q000187:drug effects / Q000502:physiology / Q000528:radiation effects*; D014466:Ultraviolet Rays
D004273:DNA, Neoplasm; D011564:Furocoumarins; D012334:RNA, Neoplasm; C023026:5-methylangelicin