title: Time factor in oxygen transfer from mother to fetus.
abstract: The time factor in the oxygen transfer from mother to fetus was studied by the tcPO2 technique. When a fairly constant fetal circulation made estimation possible, the decrease in fetal tcPO2 synchronous with and due to the uterine contractions in more than 400 events was always delayed 50--60 sec. Since the time lag in the increase in fetal tcPO2 following administration of pure oxygen to the mother was found to be of the same order of magnitude, the placental part of the delay in the oxygen transfer from mother to fetus can be assumed to be 50--60 sec. This determination supports the prevalent hypothesis that type II dips or late decelerations in the fetal heart rate are caused by hypoxia while type I dips or early decelerations are initiated by other factors.
mesh_terms: D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D005318:Fetal Heart / Q000502:physiology; D006339:Heart Rate; D006801:Humans; D008431:Maternal-Fetal Exchange; D010100:Oxygen / Q000008:administration & dosage / Q000097:blood*; D010313:Partial Pressure; D010920:Placenta / Q000098:blood supply / Q000378:metabolism; D011247:Pregnancy; D013997:Time Factors; D014590:Uterine Contraction
chemical_list: D010100:Oxygen