[Biochemical studies on histones of the central nervous system. II. Acetylation of histones from neurons and glia of the rat brain in vitro].
There are no qualitative differences in the electrophoretic patterns of histones from neurones and glia. A 25% increased acetylation rate is found in neuronal histones as compared to glial histones after incubation of chopped brain in a [14C]-acetate containing medium. This result probably reflects different condensation states of the chromatins of both cell types, as demonstrated by electron microscopy.
D000085:Acetates / Q000378:metabolism; D000107:Acetylation; D000818:Animals; D001921:Brain / Q000378:metabolism; D001923:Brain Chemistry; D004591:Electrophoresis, Polyacrylamide Gel; D006657:Histones / Q000032:analysis*; D008297:Male; D009457:Neuroglia / Q000032:analysis* / Q000378:metabolism / Q000648:ultrastructure; D009474:Neurons / Q000032:analysis* / Q000378:metabolism / Q000648:ultrastructure; D051381:Rats
D000085:Acetates; D006657:Histones
Biochemische Untersuchungen an Histonen des Zentralnervensystems. II. Azetylierung von Histonen aus Neuronen und Glia des Rattenhirns in vitro.