Posttraumatic anterior pituitary insufficiency in childhood.
5 patients are presented in whom cerebral trauma of varying intensity during childhood was followed by pituitary insufficiency. There was no correlation between the severity of injury and subsequent hormonal defects. Among other anterior pituitary hormone defects, growth retardation secondary to growth hormone deficiency is a predominant feature in the pediatric age group. Only one patient requires treatment of neurohormonal diabetes insipidus. The prevalence of traumatic origin among the hypopituitary dwarfs observed in our departement is 3.7%.
D000293:Adolescent; D045930:Anabolic Agents / Q000627:therapeutic use; D001827:Body Height; D001930:Brain Injuries / Q000150:complications; D002648:Child; D002675:Child, Preschool; D006259:Craniocerebral Trauma / Q000150:complications*; D003919:Diabetes Insipidus / Q000209:etiology; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D006130:Growth Disorders / Q000209:etiology; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D007018:Hypopituitarism / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D012887:Skull Fractures / Q000150:complications; D013963:Thyroid Hormones / Q000627:therapeutic use
D045930:Anabolic Agents; D004967:Estrogens; D013963:Thyroid Hormones; D013006:Growth Hormone