title: [NIH potency tests with inactivated rabies vaccines (author's transl)].
abstract: 63 NIH tests were analysed. A BPL inactivated tissue culture rabies vaccine No. 108 was compared with the national standard vaccine A 18 fourteen times in different tests. The results show that reproduction of results is unsatisfactory with the NIH test and that this test in its present traditional method with two injections is not very suitable for satisfactory potency evaluation of inactivated rabies vaccines. Proposals for modifications are made.
mesh_terms: D000818:Animals; D046508:Culture Techniques; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005260:Female; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D011819:Rabies Vaccines / Q000276:immunology / Q000592:standards* / Q000633:toxicity
chemical_list: D011819:Rabies Vaccines
vernacular_title: Zur Wirksamkeitsprüfung von inaktivierten Tollwut-Gewebekulturimpfstoffen im NIH-Test.