The chemotactic effect of Bacteroides fragilis lipopolysaccharide.
The atypical Bacteroides fragilis lipopolysaccharide is chemotactic for polymorphonuclear leukocytes. The chemotactic activity is mediated by complement activated through the alternative pathway. This mediator has been isolated. It is a polypeptide with a molecular weight of 16,000 and is most likely the complement component C5a.
D000818:Animals; D001441:Bacteroides fragilis / Q000276:immunology*; D002630:Chemotactic Factors; D003182:Complement C5 / Q000276:immunology; D003170:Complement Pathway, Alternative / Q000187:drug effects; D011135:Polysaccharides, Bacterial / Q000494:pharmacology*; D011817:Rabbits
D002630:Chemotactic Factors; D003182:Complement C5; D011135:Polysaccharides, Bacterial