title: On the metabolic detoxication of thymol in rabbit and man.
abstract: The metabolic detoxication of thymol was investigated in rabbit and man. Thymol glucuronide which the aglycone is intact, was isolated from thymol medicated rabbit urine and identified as a acetyl derivative of methyl glucuronate. The hydroxylated product of thymol, thymohydroquinone, was recognized in a small amount in thymol medicated human urine. It was presumed that thymohydroquinone is excreted as ethereal sulfuric acid conjugate in man.
mesh_terms: D000818:Animals; D005965:Glucuronates / Q000652:urine; D006801:Humans; D006868:Hydrolysis; D006900:Hydroxylation; D008658:Inactivation, Metabolic; D011817:Rabbits; D013045:Species Specificity; D013943:Thymol / Q000378:metabolism* / Q000633:toxicity / Q000652:urine; D013997:Time Factors
chemical_list: D005965:Glucuronates; D013943:Thymol