A comparison of two technetium-99m-labeled radiopharmaceuticals for lymphoscintigraphy: concise communication.
A comparison of stannous phytate and antimony sulfide colloid, both labeled with Tc-99m, was conducted during the performance of internal mammary lymphoscintigraphy in 46 patients. Thirteen of these patients were randomized to receive both radiotracers in two consecutive studies. The results indicated a statistical difference between agents; Tc-99m antimony sulfide allowed visualization of a greater number of more intense nodes, better delineation of the total length of the internal mammary lymph-node chain, and a more consistent visualization of supraclavicular nodes. Although previously published animal data suggest utility of Tc-99m stannous phytate for lymph-node imaging, Tc-99m antimony sulfide was shown in this clinical comparison to provide a more reliable representation of lymph-node anatomy.
D000965:Antimony; D001943:Breast Neoplasms / Q000000981:diagnostic imaging; D003102:Colloids; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D015609:Organotechnetium Compounds; D010833:Phytic Acid; D011877:Radionuclide Imaging; D013667:Technetium; D017556:Technetium Compounds
D003102:Colloids; D015609:Organotechnetium Compounds; D017556:Technetium Compounds; C019096:technetium Tc 99m antimony sulfide; C019099:technetium Tc 99m stannous phytate; D013667:Technetium; D010833:Phytic Acid; D000965:Antimony