Liver damage due to perhexiline maleate.
Two middle-aged men, who had received perhexiline in recommended dosage, showed clinical and histological evidence of severe hepatic damage, and one of them died. Histological study of the livers showed a striking resemblance to alcoholic hepatitis.
D056486:Chemical and Drug Induced Liver Injury; D003937:Diagnosis, Differential; D006519:Hepatitis, Alcoholic / Q000175:diagnosis; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010480:Perhexiline / Q000009:adverse effects*; D010880:Piperidines / Q000009:adverse effects*
D010880:Piperidines; D010480:Perhexiline