Testing for potential thrombogenicity of prothrombin complex concentrates.
The methods used in the author's laboratory for testing for potential thrombogenicity in prothrombin complex concentrates are described and compared critically. Alternative methods of presenting the results of these test systems are discussed. Changes in fractionation procedure which have resulted in improved performance of concentrates in one or more of the tests are discussed.
D000990:Antithrombin III; D005164:Factor IX / Q000032:analysis; D006493:Heparin; D006801:Humans; D010314:Partial Thromboplastin Time; D011516:Prothrombin / Q000032:analysis*; D011786:Quality Control; D013917:Thrombin / Q000032:analysis
D000990:Antithrombin III; D011516:Prothrombin; D005164:Factor IX; D006493:Heparin; D013917:Thrombin