title: Treatment of intraocular proliferations with intravitreal steroids.
abstract: Autotransplantation of 250,000 tissue cultured fibroblasts from rabbit rump skin into the vitreous cavity results in intravitreal strand formation and traction retinal detachment (27 of 47 eyes, 57%). A single intravitreal injection of 1 mg of dexamethasone alcohol inhibits fibroblast growth as judged by the significantly reduced number of retinal detachments (11 of 46 eyes, 24%).
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D003907:Dexamethasone / Q000494:pharmacology / Q000627:therapeutic use*; D005128:Eye Diseases / Q000517:prevention & control; D005347:Fibroblasts / Q000187:drug effects / Q000637:transplantation; D011817:Rabbits; D012163:Retinal Detachment / Q000209:etiology / Q000517:prevention & control*; D014182:Transplantation, Autologous; D014822:Vitreous Body / Q000187:drug effects*
chemical_list: D003907:Dexamethasone