Inhibition of Na235SO4 incorporation of granulomatous tissue by a glycosamine derivative.
The effect of N-acetyl-4-6-(p-oxy-benzylidene)-D-glycosamine on Na235SO4 incorporation has been studied in vitro. The 0.25-2.0 mmoles of the compound significantly inhibited the Na235SO4 incorporation of granulomatous tissue. The inhibitory effect proved to be dose dependent.
D000117:Acetylglucosamine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005944:Glucosamine / Q000031:analogs & derivatives*; D006025:Glycosaminoglycans / Q000096:biosynthesis; D006099:Granuloma / Q000378:metabolism*; D008297:Male; D051381:Rats; D013431:Sulfates / Q000378:metabolism*
D006025:Glycosaminoglycans; D013431:Sulfates; C025172:N-acetyl-4,6-(4-oxy-benzylidene)glycosamine; D005944:Glucosamine; D000117:Acetylglucosamine