Consumptive coagulopathy during the Bromsulphalein test--indocyanine green as an alternative.
Liver function tests involving the use of Bromsulphalein can lead to hemolysis and consequent DIC. Latent forms can be detected by means of fibrinolytic degradation products and reduction in the number of leukocytes containing acid mucopolysaccharides of the heparin type, together with an increase in the total leukocyte count as a sign of stress. In comparisons between the bromsulphalein and indocyanine green tests, these parameters have sho4n that liver function tests using indocyanine green are harmless.
D000328:Adult; D001491:Basophils; D004211:Disseminated Intravascular Coagulation / Q000139:chemically induced*; D005338:Fibrin Fibrinogen Degradation Products; D006461:Hemolysis; D006801:Humans; D007122:Immunoelectrophoresis; D007208:Indocyanine Green; D007958:Leukocyte Count; D008111:Liver Function Tests / Q000379:methods*; D013448:Sulfobromophthalein / Q000009:adverse effects*
D005338:Fibrin Fibrinogen Degradation Products; D013448:Sulfobromophthalein; D007208:Indocyanine Green