title: Use of the positive difference transform for RBC elimination in bone marrow smear images.
abstract: The use of an algorithm with a broad range of utility in digital image processing (the positive difference transform) is illustrated. Its effectiveness as a procedure for selective elimination of hemoglobin-containing images is demonstrated. A set of heuristics, employing information concerning nuclear hemoglobin content, is shown to discriminate nucleated erythrocytic cells from those of the leukocyte series.
mesh_terms: D001854:Bone Marrow Cells; D001856:Bone Marrow Examination / Q000379:methods*; D004912:Erythrocytes; D006454:Hemoglobins / Q000032:analysis; D008433:Mathematics
chemical_list: D006454:Hemoglobins