Changes in serum succinyltrialanine p-nitroanilide hydrolysing activity in hepatobiliary diseases.
Serum succinyltrialanine p-nitroanilide hydrolysing activity was elevated in patients with hepatobiliary diseases. The highest activities were seen in acute cholangitis and intrahepatic cholestasis. The change in succinyltrialanine p-nitroanilide hydrolysing activity was closely associated with those in gamma-glutamyltranspeptidase and alkaline phosphatase activities. In some cases, however, the former was more sensitive than the latter.
D000328:Adult; D000368:Aged; D000813:Anilides / Q000097:blood / Q000378:metabolism; D001649:Bile Duct Diseases / Q000201:enzymology*; D005260:Female; D006801:Humans; D006867:Hydrolases / Q000097:blood*; D006868:Hydrolysis; D008107:Liver Diseases / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D009842:Oligopeptides / Q000097:blood* / Q000378:metabolism
D000813:Anilides; D009842:Oligopeptides; C015516:succinyl-trialanine-4-nitroanilide; D006867:Hydrolases