Detection and clinical significance of functional intrapulmonary vascular anastomoses in patients with chronic nonspecific lung diseases.
In 60 patients with chronic nonspecific lung diseases, both pulmonary circulation systems were examined simultaneously by catheterization and selective angiography of bronchial and lesser circulation vessels. The value of regional oxy- and barometric measurements for the diagnostics of left-to-right shunts in the lesser circulation was proved. Complex angiological examinations of both lung circulation systems helped reveal the basic variations of intrapulmonary anastomoses in both systems in patients with chronic nonspecific lung diseases. The formation of intrapulmonary anastomoses in such patients led to regional hyperoxygenation and to pulmonary arterial hypertension in the lesser circulation (in 18% of the patients), and to functional blockade of the perfusion (in 47% of the patients) of the affected segments, lobes, or the whole lung, which phenomenon substantially influenced the clinical course of the disease.
D000328:Adult; D000792:Angiography; D001794:Blood Pressure; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008171:Lung Diseases / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000503:physiopathology; D011652:Pulmonary Circulation