A-nor steroids as post-coital contraceptives in the hamster with special reference to the transport and degeneration of eggs.
Two A-nor steroids, Anordrin and H241, showed a marked antifertility effect when given orally to hamsters at 10 mg/kg/day for three or four days after mating. Further study indicated that the antifertility effect was due to a disturbance of egg transport, retarded development and degeneration of fertilized eggs.
D000818:Animals; D002970:Cleavage Stage, Ovum / Q000187:drug effects; D003281:Contraceptives, Postcoital; D006224:Cricetinae; D010064:Embryo Implantation / Q000187:drug effects; D005187:Fallopian Tubes; D005260:Female; D009635:Norandrostanes / Q000494:pharmacology*; D010060:Ovulation / Q000187:drug effects; D010063:Ovum / Q000187:drug effects*; D010066:Ovum Transport / Q000187:drug effects*; D011817:Rabbits; D014599:Uterus
D003281:Contraceptives, Postcoital; D009635:Norandrostanes; C023615:anordiol; C010855:anordrin