Use of antibodies to purified Newcastle disease virus glycoproteins for strain comparisons and characterizations.
The H/N and F1 glycoproteins responsible for hemagglutinin/neuraminidase (H/N) activity and fusion (F1) activity were purified from several Newcastle disease virus strains and used to produce antisera. These antisera can be used to clearly distinguish the virus strains by a number of techniques including radioimmunoassay, and so provide a means of classifying new virus isolates. The variations detected between strains are not related to field virulence.
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D004591:Electrophoresis, Polyacrylamide Gel; D006023:Glycoproteins / Q000032:analysis* / Q000276:immunology; D006459:Hemolysin Factors; D009439:Neuraminidase / Q000378:metabolism; D009500:Neutralization Tests; D009522:Newcastle disease virus / Q000145:classification* / Q000201:enzymology / Q000276:immunology; D011817:Rabbits; D011863:Radioimmunoassay; D010948:Viral Plaque Assay
D000914:Antibodies, Viral; D006023:Glycoproteins; D009439:Neuraminidase