Reduced adhesiveness between skin fibroblasts from patients with Duchenne muscular dystrophy.
The intercellular adhesiveness of skin fibroblasts from patients with Duchenne muscular dystrophy and normal controls has been measured by determining the collision efficencies of cells using the couette viscometer. The collision efficencies for dystrophic cells were significantly lower that those for normal cells (0.01 greater than P greater than 0.005), indicating that dystrophic cells are less adhesive than normal cells.
D000328:Adult; D002448:Cell Adhesion; D002449:Cell Aggregation; D002648:Child; D002675:Child, Preschool; D005347:Fibroblasts / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure; D006801:Humans; D009136:Muscular Dystrophies / Q000503:physiopathology*; D012867:Skin / Q000503:physiopathology* / Q000648:ultrastructure; D014357:Trypsin / Q000494:pharmacology
D014357:Trypsin