title: Lethality of radioisotopes in early mouse embryos.
abstract: The development of pre-implantation mouse embryos was found to be prevented by exposure of the embryos to [35S]methionine, but not to [3H]methionine. Such embryos have also been shown to be highly sensitive to [3H]thymidine. These observations are discussed with reference to the path lengths and energies of electrons emitted from the different radioisotopes.
mesh_terms: D000818:Animals; D001755:Blastocyst / Q000528:radiation effects*; D002460:Cell Line; D002470:Cell Survival / Q000528:radiation effects; D002875:Chromosomes / Q000528:radiation effects; D008715:Methionine; D051379:Mice; D009374:Neoplasms, Experimental / Q000648:ultrastructure; D013462:Sulfur Radioisotopes; D013724:Teratoma / Q000648:ultrastructure; D014316:Tritium
chemical_list: D013462:Sulfur Radioisotopes; D014316:Tritium; D008715:Methionine