Tolerance of guaiacolic ester of acetylsalicylic acid by patients with aspirin-asthma.
The effects of oral administration of the guaiacolic ester of acetylsalicylic acid (ASA-G) on the ventilatory function were studied by means of a body plethysmograph, in a group of nine ASA-asthmatic patients. No differences in specific airway resistance were observed between ASA-G and placebo. It is concluded that ASA-G is tolerated by patients with ASA-induced asthma.
D000403:Airway Resistance / Q000187:drug effects; D001241:Aspirin / Q000009:adverse effects* / Q000031:analogs & derivatives* / Q000494:pharmacology; D001249:Asthma / Q000139:chemically induced*; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos; D010991:Plethysmography; D012119:Respiration / Q000187:drug effects
D010919:Placebos; D001241:Aspirin; C023557:guacetisal