Clinico-pathologic correlation in non-Hodgkin's lymphoma. II. Clinical and prognostic significance of nodularity.
A retrospective review of 302 patients with non-Hodgkin's lymphoma is reported. The tumors were classified according to a modified Lukes & Collins scheme and their growth pattern was analysed. Nodular growth was scored in 3 degrees. Nodularity was found to be correlated with certain clinical features and of great relevance for prognosis. The growth pattern was also correlated with cell type, but even within a certain cytologic type, nodular tumors were associated with better survival than diffuse tumors.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008223:Lymphoma / Q000401:mortality / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D012737:Sex Factors