[Morphological changes in the central canal of the cat after kaolin injection into the cisterna magna].
40 adult cats were made hydrocephalic by intracisternal injection of 200 mg Kaolin. 34 survived between 24 hours to 4 months. In 19 cases a ventriculostomy was carried out, whereby in 13 animals a contrast filling of the central canal occurred. The contrast medium injected into the ventricles entered the external CSF-space in the lumbo-sacral junction of the filum terminale. Light- and electron-microscopic studies showed adaptive structural changes of the central canal epithelium in the early stages. In later stages massive destructions of ependyma and spinal cord parenchyma were found.
D000818:Animals; D002415:Cats; D002467:Cell Nucleus / Q000648:ultrastructure; D002946:Cisterna Magna; D004805:Ependyma / Q000648:ultrastructure; D004848:Epithelium / Q000648:ultrastructure; D006849:Hydrocephalus / Q000139:chemically induced / Q000473:pathology*; D007365:Intercellular Junctions / Q000648:ultrastructure; D007616:Kaolin / Q000008:administration & dosage; D008928:Mitochondria / Q000648:ultrastructure; D009192:Myelography; D009457:Neuroglia / Q000648:ultrastructure; D013116:Spinal Cord / Q000648:ultrastructure*
D007616:Kaolin
Morphologische Veränderungen am Zentralkanal der Katze nach Kaolin-Injektion in die Cisterna magna.