title: The effect of lidocaine on succinylcholine-induced rise in intraocular pressure.
abstract: The effect of lidocaine on the increase of intraocular pressure induced by succinylcholine was studied in patients 6 to 85 years of age. Three groups of patients were studied. One group of eight patients received lidocaine 1 mg.kg-1 before succinylcholine and a control group of ten patients did not have lidocaine. Anaesthesia was induced with thiopentone 5 mg.kg-1 and maintained with nitrous oxide 50 per cent with oxygen and halothane 1.0-1.5 per cent. The tracheae of all patients were intubated. Lidocaine in doses of 1.0 to 2.0 mg.kg-1 did not prevent transient rise in intraocular pressure following administration of succinylcholine and tracheal intubation.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D007442:Intubation, Intratracheal; D008012:Lidocaine / Q000494:pharmacology*; D008875:Middle Aged; D011229:Preanesthetic Medication; D013390:Succinylcholine / Q000037:antagonists & inhibitors*
chemical_list: D008012:Lidocaine; D013390:Succinylcholine