Septum and adrenocortical function.
Dorsal septum is an intermediary centre in between the hippocampus and hypothalamus and it has got inhibitory influence over the hypothalamo-pituitary-adrenal axis. Stimulation of the dorsal septum manifested with fall in adrenocortical output whereas its lesion has opposite response. Ventral septum is a facilitatory area regarding activation of the hypothalamo-pituitary-adrenal axis. It is a balancing centre lying in between the higher central nervous system structures and the hypothalamus. Stimulation and lesion of the ventral septum led to rise and fall in adrenal venous 17-OHCS output respectively. Adrenocortical response to stress of burn was not blocked or inhibited following lesion of the dorsal as well as ventall septum.
D015065:17-Hydroxycorticosteroids / Q000097:blood; D000302:Adrenal Cortex / Q000502:physiology*; D000818:Animals; D001921:Brain / Q000502:physiology*; D002056:Burns / Q000378:metabolism; D004285:Dogs; D004558:Electric Stimulation; D008297:Male; D013997:Time Factors
D015065:17-Hydroxycorticosteroids