Lack of correlation between interferon production of mononuclear cells and virus replication in chronic hepatitis B virus infection.
Interferon production in hepatitis B virus carriers with normal liver functions was preserved, whereas in carriers with chronic hepatitis it was depressed. The lower interferon production in hepatitis B virus carriers with chronic hepatitis appears to be the result rather than the cause of chronic hepatic disease.
D002353:Carrier State; D002908:Chronic Disease; D004259:DNA-Directed DNA Polymerase / Q000378:metabolism; D006509:Hepatitis B / Q000097:blood* / Q000382:microbiology; D006515:Hepatitis B virus / Q000201:enzymology / Q000254:growth & development; D006801:Humans; D007372:Interferons / Q000096:biosynthesis*; D009000:Monocytes / Q000378:metabolism*
D007372:Interferons; D004259:DNA-Directed DNA Polymerase