Hyponatremia in myxedema: a suggested therapeutic approach.
Two patients with myxedema coma and extreme hyponatremia associated with the syndrome of inappropriate secretion of antidiuretic hormone are described. Both recovered following i.v. hypertonic saline, furosemide and thyroxine. A review of 22 cases from the literature suggests that this therapeutic approach could improve the poor prognosis in this condition.
D000368:Aged; D005260:Female; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D007010:Hyponatremia / Q000188:drug therapy / Q000209:etiology*; D007177:Inappropriate ADH Syndrome / Q000150:complications; D009230:Myxedema / Q000150:complications* / Q000188:drug therapy; D012462:Saline Solution, Hypertonic / Q000627:therapeutic use; D013974:Thyroxine / Q000627:therapeutic use
D012462:Saline Solution, Hypertonic; D005665:Furosemide; D013974:Thyroxine