title: Long-term treatment of hypertension with labetalol.
abstract: 1 Thirty-two hypertensive patients have been treated with labetalol for periods of up to 7 years. 2 Ten patients observed for 6 years from time of stabilization of dosage, did not show any tolerance to labetalol. 3 Postural and exercise hypotension were not seen in these patients over this prolonged follow-up, although they were seen in other patients given over 2 g labetalol daily.
mesh_terms: D000328:Adult; D000368:Aged; D001772:Blood Cell Count; D001794:Blood Pressure / Q000187:drug effects; D001835:Body Weight; D004361:Drug Tolerance; D004983:Ethanolamines / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007741:Labetalol / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D011187:Posture; D013997:Time Factors
chemical_list: D004983:Ethanolamines; D007741:Labetalol