Serologic responses to treatment of 128 patients with late latent syphilis.
One hundred twenty-eight patients who had been treated for late latent syphilis were followed. Benzathine penicillin G (2.4 X 10(6) units given intramuscularly once a week for two weeks) was administered to 123 patients, and five patients were given tetracycline (500 mg orally four times daily for 12 days). Of these patients, 56 (44%) became seronegative within five years, and 72 (56%) had persistently positive reagin tests.
D000328:Adult; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010401:Penicillin G Benzathine / Q000627:therapeutic use; D011935:Reagins / Q000032:analysis; D013588:Syphilis Serodiagnosis; D013592:Syphilis, Latent / Q000188:drug therapy* / Q000276:immunology; D013752:Tetracycline / Q000627:therapeutic use
D011935:Reagins; D013752:Tetracycline; D010401:Penicillin G Benzathine