title: Evolution of endemic goiter in the Valea Jiului area after 30 years of iodine prophylaxis.
abstract: After 30 years of iodine prophylaxis the incidence of goiter in the Valea Jiului area was reassessed. A number of 7,892 pupils aged 7-16 years were examined, of whom goiter was found in 32%. Before iodine prophylaxis started the incidence was 91.8%. The present survey shows that the small-sized goiters markedly prevail over middle-sized ones, while large-sized goiters became extinct. The diffuse to nodular goiter ratio changed by the disappearance of the nodular forms. The neurologic and psychic complications in goiter-bearing children disappeared. Attempts to correlate taste sensitivity to thiocarbamide with goiter failed. Examination of the digito-palmar dermatoglyphics showed a greater incidence of the higher atd angle, with transition forms of sulcus palmaris.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001824:Body Constitution; D002648:Child; D005260:Female; D006043:Goiter, Endemic / Q000453:epidemiology* / Q000517:prevention & control; D006044:Goiter, Nodular / Q000453:epidemiology; D006801:Humans; D007455:Iodine / Q000627:therapeutic use*; D008297:Male; D012383:Romania; D012737:Sex Factors
chemical_list: D007455:Iodine