A comparison of six procedures for compatibility testing.
Six procedures for compatibility testing were compared, using red blood cells sensitized in normal saline, albumin or low-ionic strength saline (LISS) combined with either broad spectrum or anti-IgG antiglobulin testing (AGT). Despite shortened incubation times, tests employing LISS were as sensitive as those with albumin and broad spectrum AGT and more sensitive than the other four combinations. No false positive results were found. LISS technique with broad spectrum AGT appears to be suitable and superior for routine antibody detection and compatibility tests.
D001788:Blood Grouping and Crossmatching; D003298:Coombs Test; D004375:Duffy Blood-Group System; D004912:Erythrocytes / Q000276:immunology; D005189:False Positive Reactions; D006801:Humans; D007626:Kell Blood-Group System; D007983:Lewis Blood Group Antigens; D009994:Osmolar Concentration; D012710:Serum Albumin, Bovine; D012965:Sodium Chloride; D013997:Time Factors
D004375:Duffy Blood-Group System; D007626:Kell Blood-Group System; D007983:Lewis Blood Group Antigens; D012710:Serum Albumin, Bovine; D012965:Sodium Chloride