Effect of pulmonary artery ligation on the developing fetal lung.
Ligation of the left pulmonary artery was performed in fetal lambs. The procedure was well tolerated and most animals survived to birth. At birth, the animals were in no distress but had mild pulmonary hypertension. The lung to which the pulmonary artery was ligated underwent normal intrauterine maturation.
D000818:Animals; D005260:Female; D005333:Fetus / Q000601:surgery*; D008026:Ligation; D008168:Lung / Q000000981:diagnostic imaging / Q000196:embryology* / Q000473:pathology; D011247:Pregnancy; D011651:Pulmonary Artery / Q000000981:diagnostic imaging / Q000601:surgery*; D011859:Radiography; D011877:Radionuclide Imaging; D012756:Sheep