Analysis of the antagonistic effect of gamma-L-glutamyl-taurine on glucocorticoid and triiodothyronine.
gamma-L-Glutamyl-taurine, a newly discovered parathyroid hormone, considerably inhibited the cytochemically detected transcription-inducing effect (appearance of free histone) of prednisolone and triiodothyronine. Such an inhibition took place also if the morphogenetic hormones were given not simultaneously with, but after the administration of litoralon. Litoralon injected alone also displayed inductor properties increasing the number of nuclei containing free histone.
D000818:Animals; D002467:Cell Nucleus / Q000032:analysis; D005973:Glutamine / Q000031:analogs & derivatives* / Q000494:pharmacology; D006657:Histones / Q000032:analysis; D008099:Liver / Q000166:cytology; D008297:Male; D010281:Parathyroid Hormone / Q000494:pharmacology*; D011239:Prednisolone / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D051381:Rats; D013654:Taurine / Q000031:analogs & derivatives* / Q000494:pharmacology; D014158:Transcription, Genetic / Q000187:drug effects*; D014284:Triiodothyronine / Q000037:antagonists & inhibitors* / Q000494:pharmacology
D006657:Histones; D010281:Parathyroid Hormone; D014284:Triiodothyronine; D005973:Glutamine; D013654:Taurine; D011239:Prednisolone