title: Bowenoid lesions, Bowen's disease and keratoacanthomas in long-term PUVA-treated patients.
abstract: Four patients are described, two with histologically proven multiple foci of bowenoid lesions, one patient with bowenoid lesions and Bowen's disease, and one patient with two keratoacanthomas, most of the lesions occurring in non sun-exposed but photochemically treated areas of the body. These patients had received long-term PUVA treatment for their psoriasis. Two patients had a history of arsenic intake. The possible relationship of these epidermal lesions to light treatment is discussed.
mesh_terms: D000328:Adult; D000368:Aged; D001151:Arsenic / Q000009:adverse effects; D001913:Bowen's Disease / Q000209:etiology* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D011564:Furocoumarins / Q000009:adverse effects*; D006801:Humans; D007636:Keratoacanthoma / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy / Q000009:adverse effects*; D011230:Precancerous Conditions / Q000209:etiology / Q000473:pathology; D011565:Psoriasis / Q000188:drug therapy; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology; D013997:Time Factors
chemical_list: D011564:Furocoumarins; D001151:Arsenic