[Dyskinetic-athetosic syndrome in a patient with prior radiculo-myelo-encephalopathy of probable viral origin. Therapeutic guidelines with levodopa and preliminary results].
The regulation of skeletal muscle tone and of the automatic and half-automatic movements by the extrapyramidal system in briefly discussed. The essential importance to keep separated the akinetic-hypertonic syndromes from the hypotonic-hyperkinetic ones is further confirmed. In fact two different chemical mediating agents work separately in these two cases: the Dopamine for the Nigro-Striatal system and the Ach for other tracts whose anatomy is still not well known, but which surely belong to the extrapyramidal system. Further more a clinical case of dyskinetic-athetosic post-infective syndrome, successfully treated with L.D., is discussed. The effectiveness of neuroleptic drugs in these hypotonic-hyperkinetic syndrome is stressed while they cause and worsen extra-pyramidal symptoms such as hypertonia and akynesia (hypertonic akinetic s.).
D001264:Athetosis / Q000188:drug therapy / Q000209:etiology; D002493:Central Nervous System Diseases / Q000150:complications*; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D009069:Movement Disorders / Q000188:drug therapy* / Q000209:etiology; D014777:Virus Diseases / Q000150:complications*
D007980:Levodopa
Sindrome discinetico-atetosica in paziente con pregressa radicolo-mielo-encefalopatia di verosimile etiologia virale. Indirizzo terapeutico con levodopa e primi risultati.