title: [Juvenile melanoma; a clinical and histological study].
abstract: Investigations were carried out in 52 female and 18 male patients, aged between 2 and 49 years, with juvenile melanoma. The tumor occured as a solitary tumor in all cases except one. It was mainly localized on the head (54%), and the extremities, on the trunk in three cases only. In 35% the tumor could be diagnosed clinically. Light microscopy revealed in 37.1% spindle cells, in 17.1% epitheloid cells, and in 45.7% the juvenile melanoma was of the mixed type. A proliferation of the vascular endothelial cells (37.1%) as well as immature looking mast cells in the tumor region were prominent findings. A transepidermal elimination of tumor cell nests was noted in one case. The other results are in agreement with earlier descriptions of this tumor.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000098:blood supply / Q000473:pathology*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000098:blood supply / Q000473:pathology; D012878:Skin Neoplasms / Q000098:blood supply / Q000473:pathology*
vernacular_title: Das juvenile Melanom; Eine klinische und histologische Untersuchung.