14C-Thiourea binding in the rat lung.
Results of the present study demonstrate that in vitro covalent binding of radioactivity from the edematogenic agent [14C] thiourea to rat lung protein can occur under aerobic and anaerobic conditions. Binding of thiourea to lung protein is associated with a reduction in glutathione. The binding of [14C] from thiourea to lung protein is temperature dependent.
D000332:Aerobiosis; D000693:Anaerobiosis; D000818:Animals; D005978:Glutathione / Q000378:metabolism; D066298:In Vitro Techniques; D008168:Lung / Q000378:metabolism*; D008297:Male; D011485:Protein Binding; D051381:Rats; D013890:Thiourea / Q000378:metabolism*; D013997:Time Factors
D005978:Glutathione; D013890:Thiourea