Inhibition of human blood platelet aggregation by photochemotherapy in vitro and in vivo.
Irradiation of human blood platelets with UV-A in vitro impairs their ability to aggregate after challenge with collagen. There also appears to be mild and transient inhibition of platelet aggregability in psoriatics during the fourth week of photochemotherapy.
D000328:Adult; D000875:Anthralin / Q000627:therapeutic use; D003094:Collagen / Q000494:pharmacology; D006801:Humans; D008730:Methoxsalen / Q000494:pharmacology / Q000627:therapeutic use; D010778:Photochemotherapy; D010974:Platelet Aggregation / Q000187:drug effects* / Q000528:radiation effects; D011565:Psoriasis / Q000097:blood / Q000188:drug therapy; D013997:Time Factors; D014466:Ultraviolet Rays
D003094:Collagen; D008730:Methoxsalen; D000875:Anthralin