Separation of standard opiates and their analysis in pharmaceutical and illicit preparations by paired-ion reverse-phase high-pressure liquid chromatography.
The separation of standard opiates in a mixture and their analysis in clandestine and pharmaceutical preparations were accomplished by PIC on a micro-Bondapak C18 column. The identification of the opiates was based on two parameters: retention times and the ratios of absorbance peaks recorded at 254 and 280 nm. No prior clean-up procedure of samples was required for analysis by this method. Baseline separation of drug components in clandestine and in pharmaceutical preparations made this method suitable for their quantitation.
D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003932:Heroin / Q000032:analysis; D013287:Illicit Drugs / Q000032:analysis*; D009022:Morphine Derivatives / Q000032:analysis*; D009269:Nalorphine / Q000032:analysis; D009294:Narcotics / Q000032:analysis*; D010208:Papaverine / Q000032:analysis; D004364:Pharmaceutical Preparations / Q000032:analysis*
D013287:Illicit Drugs; D009022:Morphine Derivatives; D009294:Narcotics; D004364:Pharmaceutical Preparations; D003932:Heroin; D010208:Papaverine; D009269:Nalorphine