title: Immunological evaluation of children undergoing tonsillectomy.
abstract: This study was carried out on 80 patients undergoing tonsillectomy for chronic tonsillitis. Twenty healthy school children in the same age group were investigated for control values. Ten children were also available for evaluation of any immunological change after tonsillectomy. No significant variation was seen in the serum IgG, IgA, and IgM levels before and after tonsillectomy. Peripheral absolute lymphocyte count was higher in the pre-operative cases as compared to the control group, and this count became near normal following tonsillectomy. Skin tests with recall antigens PPD and Candida and contact sensitizing agent 2:4 DNCB showed an improved cell mediated immune response following tonsillectomy.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000917:Antibody Formation; D001798:Blood Proteins / Q000032:analysis; D002175:Candida / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004137:Dinitrochlorobenzene / Q000276:immunology; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis; D007958:Leukocyte Count; D008214:Lymphocytes; D008297:Male; D010033:Otitis Media / Q000276:immunology; D013997:Time Factors; D014068:Tonsillectomy; D014069:Tonsillitis / Q000276:immunology*
chemical_list: D001798:Blood Proteins; D004137:Dinitrochlorobenzene; D007136:Immunoglobulins