Metabolism of protriptyline by rabbit liver in vitro.
A new metabolite of protriptyline formed by incubation of the drug in a rabbit liver microsomal system was identified as the hydroxylamine derivative by mass spectral and NMR analysis.
D000818:Animals; D001711:Biotransformation; D003986:Dibenzocycloheptenes / Q000378:metabolism*; D066298:In Vitro Techniques; D008862:Microsomes, Liver / Q000378:metabolism*; D011530:Protriptyline / Q000378:metabolism*; D011817:Rabbits
D003986:Dibenzocycloheptenes; D011530:Protriptyline