Absorption of paraquat by rat gut in vitro. Regional differences.
The absorption of radioactively labeled paraquat was measured in rat ileum, jejunum and colon by a micro everted sac technique (Semenza and Muhlhaupt, 1969). The absorption rate increased linearly over the range of concentrations measured (10(-5) to 10(-2) M) and was enhanced by nearly 50% in the absence of sodium ions. The absorption rate decreased in the order: ileum, jejunum, colon whereby in the colon still 65% of the values of the small intestine were observed.
D000818:Animals; D003106:Colon / Q000378:metabolism; D004032:Diet; D007082:Ileum / Q000378:metabolism; D007408:Intestinal Absorption; D007583:Jejunum / Q000378:metabolism; D007700:Kinetics; D008297:Male; D010269:Paraquat / Q000378:metabolism*; D051381:Rats
D010269:Paraquat