title: Heck's disease (focal epithelial hyperplasia).
abstract: A patient and his mother noted the insidious appearance of a distinctive benign papular eruption confined to the mucosa of the lips. The clinical pattern and histologic findings fulfill the criteria of a recently described entity, focal epithelial hyperplasia. An electron microscopic search for viral particles was negative. Arguments for both a viral and a hereditary pathogenesis have been put forth, but the etiology of the condition remains controversial. This disorder may be more frequently reported as dermatologists become increasingly aware of its existence.
mesh_terms: D000328:Adult; D006801:Humans; D006965:Hyperplasia; D008047:Lip Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology*; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology*; D010241:Parakeratosis / Q000209:etiology / Q000473:pathology