Selective destruction of intestinal nervous elements by local application of benzalkonium solution in the rat.
Intestinal aganglionosis produced by serosal application of 0.1% benzalkonium solution to the colon of the rat was studied electronmicroscopically, and it was concluded that a higher susceptibility to the agent and a lower recovering ability of the nerve elements might be responsible for the phenomenon.
D000818:Animals; D001548:Benzalkonium Compounds / Q000494:pharmacology*; D003106:Colon / Q000294:innervation* / Q000648:ultrastructure; D005724:Ganglia / Q000187:drug effects / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009474:Neurons / Q000187:drug effects / Q000648:ultrastructure*; D051381:Rats
D001548:Benzalkonium Compounds