Deformed optic nerves in coisogenic albino and pigmented C57BL/6J--c2j mice.
The incidence of deformed optic nerve (DON) in C57 BL/6J--c2J mice is similar to that of a pigmented substrain of Long-Evans rats and much less than that of an albino substrain of Sprague Dawley rats. C57BL/6J--c2J albinos have no more DON than do coisogenic black mice. This suggests that albinism is not a factor in DON and that observed DON in Sprague Dawley rats are strain or substrain characteristics.
D000818:Animals; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008818:Mice, Neurologic Mutants; D009900:Optic Nerve / Q000002:abnormalities* / Q000033:anatomy & histology; D013045:Species Specificity