Acquired, transient factor X (Stuart factor) deficiency in patient with mycoplasma pneumonial infection.
A case of severe haemorrhagic diathesis due to acquired deficiency of factor X (both immunologically and in procoagulant activity) is presented. The clinical and serological features of this case indicated mycoplasma pneumonial infection. Factor X in the peripheral blood did not appear to be influenced by administration of vitamin K, prothrombin-complex concentrate, fresh plasma or fresh whole blood. Circulating inhibitors of blood coagulation were absent and systemic amyloidosis could not be demonstrated. After 20 d, factor X spontaneously returned to normal. In view of the absence of other known causes of factor X deficiency, a possible relationship with mycoplasma pneumonial infection is suggested.
D001803:Blood Transfusion; D005171:Factor X Deficiency / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D006474:Hemorrhagic Disorders / Q000188:drug therapy / Q000209:etiology / Q000628:therapy; D006801:Humans; D007020:Hypoprothrombinemias / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011019:Pneumonia, Mycoplasma / Q000097:blood / Q000150:complications*; D011516:Prothrombin / Q000627:therapeutic use; D012075:Remission, Spontaneous; D014812:Vitamin K / Q000627:therapeutic use
D014812:Vitamin K; D011516:Prothrombin