title: On the origins of high in vivo wear rates in polyethylene components of total joint prostheses.
abstract: Scanning electron microscope examination of the polyethylene components of 8 total hip and 16 total knee prostheses which had been implanted 4--96 months revealed that in many cases severe wear may not necessarily be caused by the presence of acrylic cement debris or other abrasives. The craters and cracks observed on severely worn surfaces are associated with fusion defects in the plastic itself. The fusion defects were seen to occur as a result of the low temperature necessary to mold ultrahigh molecular weight polyethylene and are (at least at present) difficult to avoid. As a consequence of the above and variability of molecular weight in this material, relatively wide variations in wear rate should be expected even in the absence of acrylic debris.
mesh_terms: D000179:Acrylates / Q000009:adverse effects; D001843:Bone Cements / Q000009:adverse effects; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D007595:Joint Prosthesis; D007720:Knee Prosthesis; D008297:Male; D008970:Molecular Weight; D011095:Polyethylenes; D011183:Postoperative Complications / Q000209:etiology / Q000473:pathology
chemical_list: D000179:Acrylates; D001843:Bone Cements; D011095:Polyethylenes