title: Chromosome variants and abnormalities detected in 51 married couples with repeated spontaneous abortions.
abstract: Chromosome analysis of 51 married couples with repeated spontaneous abortions revealed a normal female karyotype in all wives, whereas 39 (76.5%) husbands showed a normal Y chromosome, 10 (19.6%) a Yq+, one (1.9%) a Yqs and one (1.9%) two Y chromosomes. The high incidence of Yq+ found in this investigation correlates with previous reports and indicates that the risk of spontaneous abortions is increased when the male partner has a large Y chromosome.
mesh_terms: D000026:Abortion, Habitual / Q000235:genetics*; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D012306:Risk; D012729:Sex Chromosome Aberrations; D014998:Y Chromosome