Production of hydroxyl radicals and their role in the oxidation of ethanol by a reconstituted microsomal system containing cytochrome P-450 purified from phenobarbital-treated rats.
D000633:Aminopyrine N-Demethylase / Q000378:metabolism; D000818:Animals; D001589:Benzphetamine; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D000431:Ethanol / Q000378:metabolism*; D005609:Free Radicals; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D010084:Oxidation-Reduction; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology*; D051381:Rats
D005609:Free Radicals; D001589:Benzphetamine; D000431:Ethanol; D003577:Cytochrome P-450 Enzyme System; D010089:Oxidoreductases, N-Demethylating; D000633:Aminopyrine N-Demethylase; D010634:Phenobarbital