Tumor induced brain damage in rats: implications for behavioral and anatomical studies with aging animals.
In rats, spontaneously occurring tumors and infarcts induce damage which destroys or distorts regions of the brainstem and cerebral hemispheres. Despite such destruction, there may be no gross evidence of behavioral or metabolic pathology.
D000236:Adenoma / Q000150:complications*; D000375:Aging; D000818:Animals; D001522:Behavior, Animal; D001921:Brain / Q000473:pathology; D001925:Brain Damage, Chronic / Q000209:etiology* / Q000473:pathology; D002544:Cerebral Infarction / Q000209:etiology / Q000473:pathology; D008297:Male; D009374:Neoplasms, Experimental / Q000473:pathology; D010911:Pituitary Neoplasms / Q000150:complications* / Q000473:pathology; D051381:Rats