5 alpha-reductase deficiency in humans: support to the theory that 5 alpha-reduction of testosterone is an essential step in the control of LH secretion.
D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase / Q000172:deficiency*; D015113:Androstane-3,17-diol / Q000378:metabolism; D000818:Animals; D013196:Dihydrotestosterone / Q000378:metabolism; D012734:Disorders of Sex Development / Q000378:metabolism; D005246:Feedback; D005640:Follicle Stimulating Hormone / Q000097:blood / Q000378:metabolism; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism*; D008297:Male; D010088:Oxidoreductases / Q000172:deficiency*; D051381:Rats; D013739:Testosterone / Q000378:metabolism*
D013196:Dihydrotestosterone; D015113:Androstane-3,17-diol; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D010088:Oxidoreductases; D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase