Massive platelet transfusion after splenectomy in a case of myelofibrosis.
A patient with myelofibrosis complicated by massive splenomegaly underwent splenectomy to alleviate the increasing transfusion requirements and iron overload. The platelets exhibited qualitative defects pre-operatively. Following splenectomy the patient bled profusely and required massive blood and platelet transfusions. The postoperative haemorrhage was controlled by giving sufficient platelets to normalize the platelet aggregation.
D001792:Blood Platelets / Q000473:pathology; D001803:Blood Transfusion; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D010974:Platelet Aggregation; D017713:Platelet Transfusion; D011183:Postoperative Complications; D055728:Primary Myelofibrosis / Q000601:surgery*; D013156:Splenectomy