A cartilage catabolic factor from synovium.
Porcine synovium in organ culture produces a factor that causes chondrocytes to degrade their matrix. A quantitative assay for the factor, for which the cartilage of bovine nasal septum is used, is described. Evidence is presented that the catabolic factor is a protein.
D000818:Animals; D001681:Biological Assay / Q000379:methods; D002358:Cartilage, Articular / Q000187:drug effects / Q000378:metabolism*; D002417:Cattle; D005591:Chemical Fractionation; D046508:Culture Techniques; D011506:Proteins / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D013552:Swine; D013583:Synovial Membrane / Q000032:analysis*
D011506:Proteins