The identification of an epoxy-hydroxy acid as a product from the incubation of arachidonic acid with washed blood platelets.
An epoxy-hydroxy compound, 10-hydroxy-11,12-epoxy-eicosa-5,8,14-trienoic acid, has been identified as a product on incubation of arachidonic acid with washed blood platelets from human, horse, cat, dog and rabbit. Gas chromatographic - mass spectrometric (GC-MS) evidence of structure is discussed.
D015126:8,11,14-Eicosatrienoic Acid / Q000031:analogs & derivatives / Q000097:blood*; D000818:Animals; D001095:Arachidonic Acids / Q000097:blood*; D001792:Blood Platelets / Q000378:metabolism*; D002415:Cats; D055598:Chemical Phenomena; D002621:Chemistry; D004285:Dogs; D005231:Fatty Acids, Unsaturated / Q000097:blood*; D008401:Gas Chromatography-Mass Spectrometry; D006736:Horses; D006801:Humans; D007536:Isomerism; D011817:Rabbits
D001095:Arachidonic Acids; D005231:Fatty Acids, Unsaturated; D015126:8,11,14-Eicosatrienoic Acid