Copper, zinc and iron levels in the cerebrospinal fluid of copper poisoned sheep.
Copper, zinc and iron levels were measured in cerebrospinal fluid (CSF) of normal and copper poisoned sheep. Copper values were within the range recorded for humans but zinc levels were six to 20 times and iron levels were 20 to 30 times higher than values reported for humans. The amount of copper, zinc and iron in the CSF did not increase in sheep dosed with copper and hence it is unlikely that the level of copper in the CSF is related to the changes in the nervous system that have been reported in copper poisoned sheep.
D000818:Animals; D003300:Copper / Q000134:cerebrospinal fluid / Q000506:poisoning*; D007501:Iron / Q000134:cerebrospinal fluid*; D008099:Liver / Q000378:metabolism; D012756:Sheep; D012757:Sheep Diseases / Q000134:cerebrospinal fluid* / Q000139:chemically induced; D013116:Spinal Cord / Q000378:metabolism; D015032:Zinc / Q000134:cerebrospinal fluid*
D003300:Copper; D007501:Iron; D015032:Zinc