Age distribution of the incidence of contact sensitivity to standard allergens.
The incidence of contact sensitivity to standard allergens present in the daily environment, such as chromium ion, cobalt, nickel and formaldehyde, is found to decrease in the fourth decade. It strongly suggests the presence of some immunoregulation in human beings, because sensitivity to these allergens should be equal in any decade.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000485:Allergens / Q000009:adverse effects*; D002648:Child; D002857:Chromium / Q000009:adverse effects; D003035:Cobalt / Q000009:adverse effects; D003877:Dermatitis, Contact / Q000276:immunology*; D005260:Female; D005557:Formaldehyde / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects; D010328:Patch Tests; D012737:Sex Factors
D000485:Allergens; D002857:Chromium; D005557:Formaldehyde; D003035:Cobalt; D009532:Nickel