[Effect of cesium ions on the electrotropic actions of acetylcholine in the rabbit atrium].
Cs+ (15-20 mM) decreases the electrotropic vagal effects on an isolated vagal innervated rabbit atrium. By means of investigating the action potentials and the phase plane trajectories of trabeculae from the rabbit atrium using a modified single sucrose gap technique the anomalous rectification disappears and also the effect of acetylcholine (ACh) on action potential duration. We presume that the anomalous rectification should be a necessary condition of electrotropic vagal (ACh) action on the rabbit atrium.
D000109:Acetylcholine / Q000494:pharmacology*; D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D016275:Atrial Function; D002586:Cesium / Q000494:pharmacology*; D006325:Heart Atria / Q000187:drug effects; D007700:Kinetics; D008433:Mathematics; D009200:Myocardial Contraction / Q000187:drug effects*; D011817:Rabbits
D002586:Cesium; D000109:Acetylcholine
Elektrotrope Azetylcholinwirkungen auf das Vorhofmyokard unter dem Einfluss von Caesium-Ionen.