Effect of dimethylaminomethylendiphosphonate on the immobilisation osteoporosis in rats.
The influence of the immobilization on the bone by the resection of the N. ischiadicus has been examined in rats, 130--150 g and 400 g of weight. The simultaneous administration of dimethylaminomethylendiphosphonate uses to lower the differences in respect to osteodissimilation between the immobilized and not immobilized extremity, caused by immobilization.
D000818:Animals; D003714:Denervation; D004164:Diphosphonates / Q000494:pharmacology* / Q000627:therapeutic use; D005269:Femur / Q000473:pathology; D006614:Hindlimb / Q000294:innervation; D007103:Immobilization; D010024:Osteoporosis / Q000517:prevention & control*; D051381:Rats; D013977:Tibia / Q000473:pathology
D004164:Diphosphonates; C013954:N,N-dimethylaminomethane diphosphonic acid