[Diagnosis of primary hyperparathyroidism and differential diagnosis of hypercalcemia].
The leading symptom in patients with primary hyperparathyroidism (pHPT) is renal lithiasis and not osteopathy. The most abundant circulating forms of parathyroid hormone in pHPT represent COOH-terminal fragments with molecular weights ranging from 4000 to 7000. Radioimmunnoassays making use of antibodies directed to CCOH-terminal parts of human parathyroid hormone are therefore suitable in distinguishing patients with pHPT from control subjects and patients with hypercalcemia unrelated to hyperfunctioning parathyroid glands.
D001323:Autoantibodies; D003937:Diagnosis, Differential; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis*; D006961:Hyperparathyroidism / Q000175:diagnosis*; D008970:Molecular Weight; D010281:Parathyroid Hormone / Q000097:blood / Q000276:immunology
D001323:Autoantibodies; D010281:Parathyroid Hormone
Diagnose des primären Hyperparathyreoidismus und Differentialdiagnose der Hypercalciämie.