title: [Properties and significance of macro-creatine kinases (author's transl)].
abstract: Sera from seven-patients with an unusual high ratio of creatine kinase-MB versus total creatine kinase, as found in the immunoinhibition test, were investigated. In every case, the electrophoretic separation of the isoenzymes showed a slow moving band, and exclusion chromatography showed the presence of macro-creatine kinase. Further chromatographic, electrophoretic and immunological investigations indicated that the macro-creatine kinases in six cases are complexes of creatine kinase-BB linked to immunoglobulin G.
mesh_terms: D000368:Aged; D003402:Creatine Kinase / Q000378:metabolism*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G; D007527:Isoenzymes; D008875:Middle Aged; D011485:Protein Binding
chemical_list: D007074:Immunoglobulin G; D007527:Isoenzymes; D003402:Creatine Kinase
vernacular_title: Eigenschaften und Bedeutung von Makro-Kreatinkinasen.