Toxicity of antibiotic combinations for vitrectomy infusion fluid.
We have found that gentamicin 8 microgram/ml in various combinations with methicillin 25 microgram/ml, oxacillin 10 microgram/ml, clindamycin 10 microgram/ml and penicillin 80 microgram/ml to be nontoxic to the retina when used in vitreous replacement fluid.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000633:toxicity; D002981:Clindamycin / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005839:Gentamicins / Q000008:administration & dosage* / Q000633:toxicity; D007267:Injections; D008712:Methicillin / Q000008:administration & dosage; D010068:Oxacillin / Q000008:administration & dosage; D010406:Penicillins / Q000008:administration & dosage; D011817:Rabbits; D012160:Retina / Q000187:drug effects*; D014822:Vitreous Body / Q000601:surgery*
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D010406:Penicillins; D002981:Clindamycin; D008712:Methicillin; D010068:Oxacillin