title: [Local reactions after repeated tetanus vaccinations].
abstract: Subjects who had exhibited a strong local reaction after vaccination with tetanus toxoid showed a high serum antitoxin titer. This observation confirms earlier findings published in the United States. Since the falloff rate in tetanus antitoxin, year by year, is no more than 30%, such patients should not receive a new booster injection in the following 10 years unless the risk of tetanus is considered great. When boostering these persons, the dose of tetanus toxoid can be reduced to 1-2 Lf.
mesh_terms: D000328:Adult; D000368:Aged; D000917:Antibody Formation; D006801:Humans; D007117:Immunization, Secondary; D008875:Middle Aged; D013743:Tetanus Antitoxin / Q000032:analysis*; D013745:Tetanus Toxoid / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D013743:Tetanus Antitoxin; D013745:Tetanus Toxoid
vernacular_title: Lokale Reaktionen nach wiederholten Tetanusimpfungen.