Treatment of spontaneous murine lymphomas with syngeneic lymphoid cells.
Syngeneic thymus grafts and spleen cells were administered to thymectomized and intact (C57BL/1XA)F1 mice with spontaneous lymphomas. Their life span was prolonged significantly compared to untreated tumor-bearing controls. Dramatic clinical and histologic evidence of tumor regression was observed.
D000818:Animals; D008223:Lymphoma / Q000628:therapy*; D051379:Mice; D008815:Mice, Inbred Strains; D009374:Neoplasms, Experimental / Q000628:therapy; D013154:Spleen / Q000637:transplantation*; D013934:Thymectomy; D013950:Thymus Gland / Q000637:transplantation*; D014185:Transplantation, Isogeneic