title: Coexistence of different pathways in the metabolism of n-propylbenzene by Pseudomonas sp.
abstract: Pseudomonas desmolytica S449B1 and Pseudomonas convexa S107B1 grown on n-propylbenzene oxidized n-propylbenzene to beta-phenylpropionic acid and benzoic acid by initial oxidation of the n-propyl side chain and the following beta-oxidation, respectively. The same strains also oxidized n-propylbenzene to 3-n-propylcatechol by initial oxidation of positions 2 and 3 of the aromatic nucleus. A ring fission product, 2-hydroxy-6-oxononanoic acid, was also isolated from the culture broth. Together with the results of oxygen uptake experiments, the data obtained suggested not only the existence of a reductive step to form 2-hydroxy-6-oxononanoic acid, but also the coexistence of two different pathways in the metabolism of n-propylbenzene by the strains used.
mesh_terms: D001555:Benzene Derivatives / Q000378:metabolism*; D001565:Benzoates / Q000378:metabolism; D001673:Biodegradation, Environmental; D002087:Butyrates / Q000378:metabolism; D002396:Catechols / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D006880:Hydroxy Acids / Q000378:metabolism; D007651:Keto Acids / Q000378:metabolism; D010084:Oxidation-Reduction; D010101:Oxygen Consumption; D010666:Phenylpropionates / Q000378:metabolism; D011549:Pseudomonas / Q000378:metabolism*; D013045:Species Specificity
chemical_list: D001555:Benzene Derivatives; D001565:Benzoates; D002087:Butyrates; D002396:Catechols; D006880:Hydroxy Acids; D007651:Keto Acids; D010666:Phenylpropionates; C024268:n-propylbenzene; C024269:2-hydroxy-6-oxonanoic acid