Proton magnetic resonance studies on [methionine]-enkephalin and beta-endorphin in aqueous solution.
Proton magnetic resonance studies of [Met5]-enkephalin (lipotropin 61-65) in aqueous solution indicate a conformational preference for the pentapeptide backbone. The structural differences between [Met5]-enkephalin and other, more flexible peptides have been investigated using paramagnetic probe techniques. An outline structure for beta-endorphin (lipotropin 61-91) in aqueous solution is obtained from binding studies using Gd(III) as a relaxation probe.
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D004723:Endorphins; D004745:Enkephalins; D009682:Magnetic Resonance Spectroscopy; D008715:Methionine; D008968:Molecular Conformation; D010446:Peptide Fragments / Q000032:analysis; D010902:Pituitary Gland; D012996:Solutions; D013552:Swine
D004723:Endorphins; D004745:Enkephalins; D010446:Peptide Fragments; D012996:Solutions; D008715:Methionine