Total synthesis of heterocyclic steroids, Part II. Synthesis of (+/-)-17-thia-3-methoxy-8 alpha, 14 beta-estra-1,3,5(10)-triene-17-dioxide.
2-Methyl-3-oxothiophane-1-dioxide (II) was prepared and was used as the D ring precursor in the total synthesis of the title compound via modified Torgov synthesis.
D004963:Estrenes / Q000138:chemical synthesis*; D013260:Steroids, Heterocyclic / Q000138:chemical synthesis*; D013876:Thiophenes
D004963:Estrenes; D013260:Steroids, Heterocyclic; D013876:Thiophenes; C023799:2-methyl-3-oxothiophane-1-dioxide; C023798:17-thia-3-methoxy-8 alpha,14 beta-estra-1,3,5(10)-triene-17-dioxide