Total synthesis of heterocyclic steroids, Part III. Synthesis of (+/-)-3,17-dithia-A-nor-14 beta-estra-1,5(10),6,8-tetraene-17-dioxide.
With 4-oxo-4,5,6,7-tetrahydrobenzothiophene and 2-methyl-3-oxothiophane-1-dioxide (III) as AB and D ring precursors respectively, (+/-)-3,17-dithia-A-nor-14 beta-estra-1,5(10),6,8-tetraene-17-dioxide (I) was synthesised following the modified Torgov method.
D004963:Estrenes / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008722:Methods; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013260:Steroids, Heterocyclic / Q000138:chemical synthesis*
C023639:3,17-dithia-A-nor-14 beta-estra-1,5(10),6,8-tetraene-17-dioxide; D004963:Estrenes; D007202:Indicators and Reagents; D013260:Steroids, Heterocyclic