Local and Gastrointestinal reactions to intravenously administered cefoxitin and cefuroxime.
Side effects of cefoxitin and cefuroxime were noted in 2 different studies during intravenous treatment for at least 14 days. In the cefoxitin group of 33 patients thrombophlebitis was observed in 3 cases and diarrhoea in 4 cases. In the cefuroxime group of 31 patients 1 case of thrombophlebitis was noted and 5 cases of diarrhoea occurred. Most patients with diarrhoea had decreased renal function or received higher dosage of the antibodies than the other patients.
D000368:Aged; D002440:Cefoxitin / Q000008:administration & dosage / Q000009:adverse effects*; D002444:Cefuroxime / Q000008:administration & dosage / Q000009:adverse effects*; D002511:Cephalosporins / Q000009:adverse effects*; D003967:Diarrhea / Q000139:chemically induced; D005919:Glomerular Filtration Rate; D006207:Half-Life; D006801:Humans; D007275:Injections, Intravenous; D013924:Thrombophlebitis / Q000139:chemically induced
D002511:Cephalosporins; D002440:Cefoxitin; D002444:Cefuroxime