[The epidemiology of Wilson's disease in the German Democratic Republic and current problems from the viewpoint of population genetics].
Between 1949 and Nov. 30, 1977 a total of 123 cases of Wilson's disease have been registered in the GDR. Using the available statistics the incidence rate of the disease is assumed to be about 2.9/100,000, the gene frequency approx. 0.53 per cent and the heterozygote incidence 1.05 per cent, supposing that the Hardy-Weinberg law applies to a large extent. Conclusions are drawn from the available material with a view to detection of the disease infuture and to genetic family counselling.
D005828:Genetics, Population; D005859:Germany, East; D006527:Hepatolenticular Degeneration / Q000453:epidemiology* / Q000235:genetics; D006801:Humans
Die Epidemiologie der Wilson schen Erkrankung in der DDR und die derzeitige Problematik einer populationsgenetischen Bearbeitung.