Effect of a long term oral administration of a hypercholesterolic diet on rat liver substructures.
The effects of high cholesterol diets on ultrastructure morphologic alterations of rat liver have been investigated. It has been verified that these diets induce the biochemical and morphological damage, as well as death in a shorter time than alipidic or sole saturated lipid diets. Moreover it has been established that the anatomic irreversible damage appears at the last stage, just before death.
D000818:Animals; D002791:Cholesterol, Dietary / Q000494:pharmacology*; D004041:Dietary Fats / Q000494:pharmacology*; D004721:Endoplasmic Reticulum / Q000187:drug effects / Q000648:ultrastructure; D008099:Liver / Q000187:drug effects / Q000473:pathology / Q000648:ultrastructure*; D008297:Male; D051381:Rats
D002791:Cholesterol, Dietary; D004041:Dietary Fats