[Dependence of frog epithelial cell and neuron survival time on the concentration of certain substances].
The frog cornea epitelial cells, nervous cells of spinal ganglia and of urinary bladder have been found to survive in vitro, in the presence of subtoxical concentrations of chloral hydrate, urea, ethanol or methanol added to the Ringer solution, longer than control preparations. The above drugs added both in lower and higher concentrations lead to cell damages, thus reducing the cell survival time, which was tested by the capacity to deposit granules of a vital dye - neutral red.
D000818:Animals; D001001:Anura; D002470:Cell Survival / Q000187:drug effects; D002697:Chloral Hydrate / Q000494:pharmacology; D003315:Cornea / Q000166:cytology*; D004305:Dose-Response Relationship, Drug; D004847:Epithelial Cells; D000431:Ethanol / Q000494:pharmacology; D005727:Ganglia, Spinal / Q000166:cytology; D000432:Methanol / Q000494:pharmacology; D009474:Neurons / Q000166:cytology*; D009499:Neutral Red / Q000378:metabolism; D010275:Parasympathetic Nervous System / Q000166:cytology; D013997:Time Factors; D014508:Urea / Q000494:pharmacology; D001743:Urinary Bladder / Q000294:innervation
D009499:Neutral Red; D000431:Ethanol; D002697:Chloral Hydrate; D014508:Urea; D000432:Methanol
Zavisimost' vremeni perezhivaniia épitelial'nykh kletok i neĭronov liagushki ot kontsentratsii nekotorykh veshchestv.