The effect of ascorbic acid on RNA and protein synthesis on two cultured cell lines in vitro.
Previous work in this laboratory has thrown some light on the possible mechanism involved in the anti-tumour activity of ascorbic acid (AA). In order to elucidate this mechanism further, the present studies, involving the effect of AA on protein and RNA synthesis, were carried out. The results obtained in this investigation may support the hypothesis previously put forward for the action of AA on cell proliferation.
D001205:Ascorbic Acid / Q000494:pharmacology*; D002277:Carcinoma; D002294:Carcinoma, Squamous Cell; D002455:Cell Division; D002460:Cell Line; D006801:Humans; D007822:Laryngeal Neoplasms; D009062:Mouth Neoplasms; D009363:Neoplasm Proteins / Q000096:biosynthesis*; D012334:RNA, Neoplasm / Q000096:biosynthesis*
D009363:Neoplasm Proteins; D012334:RNA, Neoplasm; D001205:Ascorbic Acid