Differential neutralization of spontaneous and centrifuge-assisted chlamydial infectivity.
Neutralization by specific antibody of a fast-killing variant strain of Chlamydia trachomatis, which showed high spontaneous infectivity for cell monolayers, was examined. It appeared that in spontaneous infection antibody-treated chlamydiae were neutralized by inhibition of attachment to cells. Centrifugation imposed a different effect: infection was inhibited at some step at or subsequent to attachment.
D000907:Antibodies, Bacterial / Q000276:immunology*; D002478:Cells, Cultured; D002498:Centrifugation; D002692:Chlamydia trachomatis / Q000276:immunology / Q000472:pathogenicity*; D009500:Neutralization Tests
D000907:Antibodies, Bacterial