[Determinants of left ventricular function in aortic stenosis. Analysis based on pre and postoperative hemodynamic studies].
In 11 preoperative patients with aortic stenosis the isovolumic contractile indices Vpm and Vmax were normal (group N). In 8 patients with aortic stenosis these indices were depressed (group D). Peak systolic circumferential wall stress (afterload) did not differ in the two groups and showed a similar decrease after successful valve replacement. Left ventricular ejection fraction increased significantly in group D from 48 to 71% and remained unchanged in group N (70 and 75%). It is concluded that the significant improvement in ejection performance in group D at similar afterload conditions as in group N is indicative for an impaired preoperative myocardial contractile state.
D001024:Aortic Valve Stenosis / Q000503:physiopathology* / Q000628:therapy; D001794:Blood Pressure; D002302:Cardiac Output; D006350:Heart Valve Prosthesis; D006352:Heart Ventricles / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D009200:Myocardial Contraction; D011184:Postoperative Period
Determinanten der linksventrikulären Funktion bei Aortenstenose Analyse aufgrund prä- und postoperativer hämodynamischer Untersuchungen.