Synthesis of cationic cyclo-oligo(ethyleneadenine).
A novel cationic and cyclic oligo (ethyleneadenine) whose main chain has adenine ring was synthesized by the thermal polymerization of 9-(2-bromoethyl) adenine, in the solid phase. The chain extends through N-9 - N-1 and N-9 - N-7 of the adenine rings. Its molecular weight was determined to be 3960 by the sedimentation method. The micro-structure was confirmed mainly with NMR measurements. The cationic and cyclic oligo(ethyleneadenine) interacts with nucleotides and polynucleotides in neutral aqueous solution.
D000225:Adenine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D009682:Magnetic Resonance Spectroscopy; D008722:Methods; D008970:Molecular Weight; D009690:Nucleic Acid Conformation; D009711:Nucleotides; D011119:Polynucleotides
D009711:Nucleotides; D011119:Polynucleotides; C025323:9-(2-bromoethyl)adenine; D000225:Adenine