[Effect of levamisole on the cytotoxic activity of normal lymphocytes in tissue culture].
Preliminary incubation of normal non-immune spleen lymphocytes from C57BL/6j and BALB/c mice with levamisole (1 . 10(-4) - 1 . 10(-5)M) for 45 min at 37 degrees C with subsequent wash-out resulted in potentiation of the cytotoxic effect with respect to allogenic target cells (L-cells). Simultaneous administration of lymphocytes and levamisole to a culture of target cells did not produce cytotoxic effect.
D000818:Animals; D002478:Cells, Cultured; D003601:Cytotoxicity Tests, Immunologic; D007739:L Cells / Q000276:immunology; D007978:Levamisole / Q000494:pharmacology*; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D013045:Species Specificity
D007978:Levamisole
Vliianie levamizola na tsitotoksicheskuiu aktivnost' normal'nykhlimfotsitov v kul'ture tkani.