Cadmium metabolism in cdm/cdm mice.
The uptake and metabolism of cadmium by cadmium-susceptible (+/+) and cadmium-resistant (cdm/cdm) strains of mice have been compared. These strains did not differ with respect to the quantitative uptake of cadmium into liver, kidney, or testis.  After intraperitoneal administration of a nontoxic dose, more than 80% of the cadmium in liver and testis of both strains is bound to low molecular weight proteins.  The chromatographic behavior of these cadmium-binding proteins is not affected by cdm genotype.
D000818:Animals; D002104:Cadmium / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism; D005838:Genotype; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains / Q000235:genetics / Q000378:metabolism*; D013737:Testis / Q000378:metabolism
D002352:Carrier Proteins; D002104:Cadmium