Herpes simplex virus (HSV) infection of organotypic nerve cell cultures. Tubule-like structures in the nuclei of cells infected with type 2 but not with type 1 virus.
In HSV-2 infected cultures, intranuclear tubule-like structures were found more commonly in fibroblasts and central nervous system (CNS) neurons than in oligodendrocytes, astrocytes, satellite and Schwann cells, but were found least often in peripheral neurons.
D000818:Animals; D001253:Astrocytes / Q000648:ultrastructure; D002478:Cells, Cultured; D005347:Fibroblasts / Q000648:ultrastructure; D006561:Herpes Simplex / Q000473:pathology*; D051379:Mice; D009420:Nervous System / Q000648:ultrastructure*; D009474:Neurons / Q000648:ultrastructure; D009836:Oligodendroglia / Q000648:ultrastructure; D012583:Schwann Cells / Q000648:ultrastructure