In vitro effects of contrast media on the water content of human erythrocytes.
The effect of the concentration of the contrast media Visotrast 370, Dimer X and Adipiodon on the water content of human erythrocytes was analysed in vitro. While a concentration-dependent water discharge (shrinkage) of erythrocytes was found in the presence of Visotrast 370 and Dimer X, the application of Adipiodon caused water uptake (swelling). Possible causes of swelling of red blood cells despite the hyperosmolality of Adipiodon are discussed.
D003287:Contrast Media / Q000494:pharmacology*; D004912:Erythrocytes / Q000032:analysis* / Q000187:drug effects; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D014867:Water / Q000032:analysis*
D003287:Contrast Media; D014867:Water