title: [Experience with the combination mezlocillin/oxacillin in severe bacterial infections in a children's surgical ward (author's transl)].
abstract: Severe bacterial infections accompanying conditions during childhood which demand for surgical intervention mostly are caused by Staph. aureus, E. coli, Klebsiella/Aerobacter or Ps. aeruginosa. 20 patients, 10 of them suffering from a putrid peritonitis, showed a good efficacy of Optocillin (Bay 1-1330), a combination of 6-((R)-2-[3-methylsulfonyl-2-oxo-imidazolidine-1-carboxamido]-2-phenyl-acetamido)-penicillanic acid sodium salt (mezlocillin, Baypen) and 5-methyl-3-phenyl-4-isoxazolylpenicillin (oxacillin, Stapenor), in 85%. Bacteria were eliminated in 79%.
mesh_terms: D000293:Adolescent; D001424:Bacterial Infections / Q000097:blood / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000097:blood / Q000188:drug therapy; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008802:Mezlocillin; D010068:Oxacillin / Q000009:adverse effects / Q000627:therapeutic use*; D010406:Penicillins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D010406:Penicillins; D008802:Mezlocillin; D010068:Oxacillin
vernacular_title: Erfahrungen mit einer Mezlocillin-Oxacillin-Kombination bei schweren bakteriellen Infektionen in einer kinderchirurgischen Klinik.