Deposition and clearance of fibrin in the rat lung following acute haemorrhage.
The effect of acute haemorrhage on the deposition and clearance of fibrin in the rat lung after thrombin-induced intravascular coagulation was investigated. Haemorrhage was followed by less embolization of fibrin to the lungs and delayed elimination from the lungs. As lung tissue fibrinolysis was not diminished, the peripheral and pulmonary circulatory disturbance was probably in itself responsible for the observed effects.
D000208:Acute Disease; D000818:Animals; D005260:Female; D005337:Fibrin / Q000378:metabolism*; D005340:Fibrinogen / Q000378:metabolism; D005342:Fibrinolysis; D008168:Lung / Q000378:metabolism*; D011652:Pulmonary Circulation; D011655:Pulmonary Embolism / Q000097:blood; D051381:Rats; D012771:Shock, Hemorrhagic / Q000378:metabolism*; D013917:Thrombin / Q000494:pharmacology
D005337:Fibrin; D005340:Fibrinogen; D013917:Thrombin