[Hemolysis in Kala Azar: isotopic study, possible role of a PNH like defect (author's transl)].
A case of Kala Azar with prevailing hemolytic anemia is reported. The hemolysis has been associated during a short time with positive PNH test (i.e.: Crosby and sucrose tests). According to the data found in the Litterature, the hemolysis occurs quite frequently. One of the possible mechanisms is an abnormal sensitivity of the erythrocyte membrane to complement, which had not yet been described.
D000328:Adult; D000743:Anemia, Hemolytic / Q000276:immunology*; D003165:Complement System Proteins; D004910:Erythrocyte Membrane / Q000276:immunology; D005260:Female; D006801:Humans; D007504:Iron Radioisotopes; D007898:Leishmaniasis, Visceral / Q000097:blood / Q000276:immunology*
D007504:Iron Radioisotopes; D003165:Complement System Proteins
L'hémolyse du Kala Azar. Etude isotopique, mise en évidence d'une sensibilité anormale au complément.