title: The effect of vitamin E administration to pregnant women, on the concentration of linoleic acid in adipose tissue of the newborns.
abstract: The composition of various lipids were measured in ten healthy newborns of mothers who were treated with 100 mg vitamin E per day, starting in the 35th week of pregnancy. The maternal serum vitamin E levels following the treatment (1.10 +/- 0.49 mg/dl) showed no increase as compared to the pretreatment values (1.06 +/- 0.38 mg/dl). There was no significant difference in serum vitamin E levels in those newborns whose mothers were treated--(0.19 +/- 0.12 mg/dl) as compared to 10 newborns whose mothers were not treated with vitamin E (0.13 +/- 0.07 mg/dl). However, there was a striking increase in the relative concentration of linoleic acid in the adipose tissue to those newborns whose mothers were treated (9.4%--versus--4.1%).
mesh_terms: D000273:Adipose Tissue / Q000187:drug effects / Q000378:metabolism*; D002788:Cholesterol Esters / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D008041:Linoleic Acids / Q000378:metabolism*; D011247:Pregnancy; D014280:Triglycerides / Q000378:metabolism; D014810:Vitamin E
chemical_list: D002788:Cholesterol Esters; D005230:Fatty Acids, Nonesterified; D008041:Linoleic Acids; D014280:Triglycerides; D014810:Vitamin E