title: [Population genetics approach to the problem of the nonspecific biological resistance of the human body. I. Statement of the problem and basis for the approach. Distribution parameters of anthropometric markers of normal and ill newborn infants and nurslings].
abstract: Distributions of two metrical characters-the weight and the body length at birth are considered in several groups of healthy, diseased and dead newborns and infants. Significant differences in statistical parameters of these distributions (mean, standard deviation, skewness and kurtosis) are demonstrated for normal and malformated children. The increased number of children with minimal deviations from the mean values of characters (adaptive norm) is observed among healthy newborns, while in groups of diseased and dead children the frequency of individuals with extreme (especially low) values is increased. The principle of classification of individuals based simultaneously on two characteris is suggested and the problem of "average phenotype" classification by the number of characters is discussed.
mesh_terms: D001724:Birth Weight; D001827:Body Height; D005260:Female; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000235:genetics / Q000473:pathology*; D008297:Male; D010641:Phenotype
vernacular_title: Populiatsionno-geneticheskiĭ podkhod k probleme nespetsificheskoĭ biologicheskoĭ ustoĭchivosti cheloveskogo organizma. Soobshchenie I. Postanovka problemy i obosnovanie podkhoda. Parametry raspredeleniĭ antropometricheskikh priznakov novorozhdennykh i grudnykh deteĭ v norme i patologii.