title: [Follow-up of 28 cases of hypothyroidism in children (author's transl)].
abstract: Author reports follow-up of 28 cases of hypothyroidism evaluated for a period of several years according to the following parameters: growth in weight and lenth, bone age, cortical thickness, bone diameter and linear growth prognosis. He classifies the cases according to the type of hypothyroidism and age of patient in which diagnosis was made. Two-third of the cases are female. As a whole, he considers acceptable results of the evaluation. Nevertheless, in the group of glandular dysgenesis, evaluation is poor, but it is very trustworthy in those with hormonogenesis alteration, and in the group of pituitary-hypothalamic hypothyroidism. Those patients in whom diagnosis was made before 12 months of age, the degree of impairment is lesser and the course changes only scantly by treatment. On those on which diagnosis was made after 12 months of life, are more seriously damaged and they usually need treatment for four years or more for a catch-up growth period. Early recognition is crucial and if possible, it must be carried out through newborn screening test.
mesh_terms: D000367:Age Factors; D001827:Body Height / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D005260:Female; D006128:Growth / Q000187:drug effects*; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy*; D007223:Infant; D008297:Male; D013974:Thyroxine / Q000627:therapeutic use; D014284:Triiodothyronine / Q000627:therapeutic use
chemical_list: D014284:Triiodothyronine; D013974:Thyroxine
vernacular_title: Estudio longitudinal del crecimiento y desarrollo somáticos en niños hipotiroideos bajo tratamiento específico.