title: [Some problems of Wilson's disease].
abstract: The Leipzig Center for Wilson's Disease in the GDR is charged with the registration and diagnosis of all homozygous Wilson gene carriers, the clarification of all suspected cases, including the heterozygote test, and the co-ordination of long-term treatment. At present, there are 78 recorded Wilson gene carriers living. On the basis of our own comprehensive observations and investigations over prolonged periods of time, questions concerning pathogenesis, genetics, diagnosis and therapeutic measures, including their side-effects, are dealt with.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D006580:Genetic Carrier Screening; D005859:Germany, East; D006527:Hepatolenticular Degeneration / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D006720:Homozygote; D006801:Humans; D010396:Penicillamine / Q000627:therapeutic use
chemical_list: D010396:Penicillamine
vernacular_title: Zu einigen Problemen der Wilsonschen Erkrankung.