HLA phenotypes and cadmium blood level.
The distribution of HLA phenotypes was studied and the amount of cadmium blood level was determined in a group of 100 healthy subjects. The HLA-A3 phenotype seems associated with high cadmium levels in the blood. The lymphocytes transformation test with PHA and different concentrations of cadmium indicates that A3 cells are more sensitive than others to inhibition by cadmium.
D002104:Cadmium / Q000097:blood*; D005260:Female; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D008213:Lymphocyte Activation; D008297:Male; D010375:Pedigree; D010641:Phenotype; D010835:Phytohemagglutinins / Q000494:pharmacology; D012907:Smoking
D006680:HLA Antigens; D010835:Phytohemagglutinins; D002104:Cadmium