Hepatic triglyceride and lipoprotein lipase activities of post-heparin plasma in normals and hypertriglyceridemics.
Post-heparin plasma hepatic triglyceride lipase (H-TGL) and lipoprotein lipase (LPL) activities were 8-34 and 3.5-21 (range) mu mol/ml/hr respectively in males with normal serum lipid concentrations. In females the corresponding values were 4-25 and 4-16 mu mol/ml/hr. No significant differences were observed between ages or between the two sexes. Male patients with hypertriglyceridaemia had similar activities of H-TGL but significantly lower values for LPL activities than the control males. Significant linear correlations were found between serum triglyceride concentrations and LPL activities both for males (coefficient of correlation = r = -0.64) and for females (r = -0.62).
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001827:Body Height; D001835:Body Weight; D002648:Child; D002784:Cholesterol / Q000097:blood; D002846:Chromatography, Affinity; D005260:Female; D006493:Heparin / Q000494:pharmacology*; D006801:Humans; D006951:Hyperlipoproteinemias / Q000201:enzymology* / Q000378:metabolism; D008049:Lipase / Q000097:blood / Q000378:metabolism*; D008071:Lipoprotein Lipase / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood / Q000378:metabolism
D014280:Triglycerides; D006493:Heparin; D002784:Cholesterol; D008049:Lipase; D008071:Lipoprotein Lipase