The half-life of glutamate dehydrogenase in plasma of dry and lactating dairy cows.
The clearance of glutamate dehydrogenase from plasma was measured weekly for three weeks in three dry and three lactating cows. The clearance was exponential with a mean clearance constant of 0.0488/j and means (+/- SE) half-life of 14.2 (+/- 0.77) h. There were variations among cows and among measurements in the same cow but there was no difference between the mean half-lives of GDH in lactating and dry cows. Because of the long half-life the small variations among individual cows are unlikely to affect the interpretation of increased plasma GDH activity.
D000818:Animals; D002417:Cattle / Q000097:blood* / Q000502:physiology; D005260:Female; D005969:Glutamate Dehydrogenase / Q000097:blood*; D006207:Half-Life; D007774:Lactation; D011247:Pregnancy
D005969:Glutamate Dehydrogenase