Apatite-associated arthropathy: a clinical study of 14 cases and of 2 patients with calcific bursitis.
Fourteen cases of acute calcific periarthritis and 2 cases of acute calcific bursitis are described. All patients had radiologic periarticular calcific deposits. Synovial fluid was available from 8 patients. Hydroxyapatite crystals were positively identified in 1 by x-ray diffraction analysis and by scanning and transmission electron microscopy. Apatite-associated arthropathy likely represents a form of crystal-induced inflammation. Three articular syndromes can be recognized; acute calcific periarthritis, acute (calcific) arthritis and a subacute-to-chronic arthritis resembling osteoarthritis. To improve patient classification, diagnostic criteria are proposed.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D001168:Arthritis / Q000175:diagnosis; D002061:Bursa, Synovial / Q000648:ultrastructure; D002062:Bursitis / Q000150:complications*; D002114:Calcinosis / Q000150:complications*; D005260:Female; D006621:Hip Joint / Q000000981:diagnostic imaging; D006801:Humans; D006882:Hydroxyapatites; D007719:Knee Joint / Q000000981:diagnostic imaging; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009504:Neutrophils; D010489:Periarthritis / Q000139:chemically induced* / Q000175:diagnosis; D011859:Radiography; D011877:Radionuclide Imaging; D013582:Synovial Fluid; D014961:X-Ray Diffraction
D006882:Hydroxyapatites