[Weakening of the ultraviolet ray-induced unscheduled DNA synthesis in human lymphocytes in extreme old age].
The intensity of unscheduled DNA synthesis was studied in UV-irradiated (10--15 J/m2) peripheral blood lymphocytes of 80--90 years old persons. In these extreme old age persons, reparative DNA synthesis was found sufficiently reduced in comparison with that in middle aged (20--43 years old) ones. The role of DNA repair processes in ageing is under discussion.
D000328:Adult; D000368:Aged; D000375:Aging / Q000528:radiation effects*; D002478:Cells, Cultured; D004247:DNA / Q000528:radiation effects*; D004260:DNA Repair / Q000528:radiation effects; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D014466:Ultraviolet Rays
D004247:DNA
Oslablenie indutsirovannogo ul'trafioletovymi luchami vneplanovogo sinteza DNK v limfotsitakh cheloveka v glubokoĭ starosti.