Chlorhexidine as an effective agent against Chlamydia trachomatis in vitro and in vivo.
In a small field trial, chlorhexidine (50 micrograms/ml) was as effective against clinical trachoma as topical tetracyclines or oral co-trimoxazole; in vitro, 2.5 micrograms/ml was chlamydicidal.
D002675:Child, Preschool; D002692:Chlamydia trachomatis / Q000187:drug effects*; D002710:Chlorhexidine / Q000494:pharmacology* / Q000627:therapeutic use; D006367:HeLa Cells; D006801:Humans; D010919:Placebos; D013420:Sulfamethoxazole / Q000627:therapeutic use; D013752:Tetracycline / Q000627:therapeutic use; D014141:Trachoma / Q000188:drug therapy; D014295:Trimethoprim / Q000627:therapeutic use
D010919:Placebos; D014295:Trimethoprim; D013752:Tetracycline; D013420:Sulfamethoxazole; D002710:Chlorhexidine