title: Notes on the genetics of congenital glaucoma.
abstract: Relying on the analysis of 81 non-Gypsy families with congenital glaucoma from the entire territory of Slovakia, the authors discuss the share of the genetic component in the etiology of the disease. The characteristics of the families of this series resembled those of comparable series as far as the percentage of familial occurrence, the percentage of bilateral occurrence (73.56%), the percentage of parental consanguinity (4.87%) and in the prevalence of males with a ratio of 1.55:1 are concerned. The incidence of the disease in Slovakia varies around 1 per 22,000 live-born infants. In the non-Gypsy population of Slovakia, the authors assume a multifactorial etiology.
mesh_terms: D003241:Consanguinity; D003604:Czechoslovakia; D005260:Female; D005901:Glaucoma / Q000151:congenital / Q000453:epidemiology / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010375:Pedigree; D012737:Sex Factors