title: [Peripheral macro-and microcirculatory changes in acute arterial obstruction with papaverine and trental administration].
abstract: The effect of myotropic spasmolytic drugs--papaverine and trental was studied in 54 patients with acute arterial obstruction. After intravenous injections of papaverine 55.8% of the patients developed impairment of peripheral macrohemodynamics and 52.9%--of microcirculation. The injection of trental was followed by an improvement of peripheral macro-and microcirculation in 75% of cases.
mesh_terms: D000208:Acute Disease; D001157:Arterial Occlusive Diseases / Q000188:drug therapy*; D001775:Blood Circulation / Q000187:drug effects*; D004341:Drug Evaluation; D004617:Embolism / Q000188:drug therapy; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D010208:Papaverine / Q000008:administration & dosage*; D010431:Pentoxifylline / Q000008:administration & dosage*; D011183:Postoperative Complications / Q000188:drug therapy; D013805:Theobromine / Q000031:analogs & derivatives*; D013927:Thrombosis / Q000188:drug therapy; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D010208:Papaverine; D013805:Theobromine; D010431:Pentoxifylline
vernacular_title: Izmeneniia perifericheskoĭ makro- i mikrotsirkuliatsii u bol'nykh s ostroĭ arterial'noĭ neprokhodimosti pri vvedenii papaverina i trentala.