title: Changes of maternal and fetal pituitary-adrenocortical functions during human labour.
abstract: The results of maternal 11-hydroxycorticoid (11-OHCS) determination on blood obtained from four stages of 44 spontaneous labour cases showed a strong and time-related maternal adrenocortical activation during vaginal delivery. The high 11-OHCS level in the cord blood and the increase of the 11-OHCS concentration in the amniotic fluid suggested the same response of the fetal adrenal. However, in 14 cases of elective caesarean sections the 11-OHCS levels in the cord blood and the amniotic fluid did not rise in spite of the elevated maternal plasma 11-OHCS content.
mesh_terms: D015062:11-Hydroxycorticosteroids / Q000097:blood*; D000302:Adrenal Cortex / Q000502:physiology; D000653:Amniotic Fluid / Q000032:analysis; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D006801:Humans; D007743:Labor, Obstetric; D008431:Maternal-Fetal Exchange; D010902:Pituitary Gland / Q000502:physiology; D011247:Pregnancy
chemical_list: D015062:11-Hydroxycorticosteroids