Regression of amyloidosis secondary to granulomatous ileitis following surgical resection and colchicine administration.
A patient with nephrotic syndrome was found to have amyloidosis secondary to an otherwise asymptomatic Crohn's disease. Resection of a major portion of the affected bowel and long-term colchicine therapy were followed by a complete clinical remission of the nephrotic syndrome, most probably due to a significant resolution of amyloidosis. The combination of resection of affected bowel segments, together with long-term colchicine therapy may offer a better prognosis than either method alone.
D000328:Adult; D000686:Amyloidosis / Q000209:etiology / Q000628:therapy*; D002432:Cecum / Q000601:surgery; D003078:Colchicine / Q000627:therapeutic use*; D003424:Crohn Disease / Q000150:complications*; D005260:Female; D006801:Humans; D007082:Ileum / Q000473:pathology / Q000601:surgery*; D009404:Nephrotic Syndrome / Q000150:complications
D003078:Colchicine