[Effects of gamma-oryzanol on norepinephrine contents in the brain and stomach of rats (author's transl)].
Norepinephrine (NE) content in the brain slightly but significantly increased when gamma-oryzanol (100 mg/kg, s.c.) was given once daily for 1, 5 or 10 days, while NE in the gastric area was not affected. The turnover rate of brain NE tended to decrease with the administration of gamma-oryzanol. From the results, it is likely that successive doses of gamma-oryzanol increase brain NE by inhibiting degradation or release of NE.
D000818:Animals; D001921:Brain / Q000378:metabolism; D001923:Brain Chemistry / Q000187:drug effects*; D008297:Male; D009638:Norepinephrine / Q000032:analysis* / Q000378:metabolism; D010666:Phenylpropionates / Q000494:pharmacology*; D051381:Rats; D013270:Stomach / Q000032:analysis*
D010666:Phenylpropionates; C013172:gamma-oryzanol; D009638:Norepinephrine