[The role of the platelets in myocardial infarction induced by isoproterenol in the rat (author's transl)].
The AA. suggest that the myocardial infarction induced by isoproterenol in the rat may be determined by phenomenons of intracoronaric platelets aggregation. The effects on the degree and extension of the infarctual necrotic area have been evaluated in a drug with remarkable platelets antiaggregation activity (ASL). The following parameters are considered: wet and dry weight of the organ, and tissutal CPK levels.
D000818:Animals; D001241:Aspirin / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism; D003326:Coronary Circulation; D003331:Coronary Vessels / Q000187:drug effects; D007545:Isoproterenol / Q000009:adverse effects; D009203:Myocardial Infarction / Q000097:blood / Q000139:chemically induced / Q000209:etiology*; D009206:Myocardium / Q000378:metabolism; D010974:Platelet Aggregation / Q000187:drug effects*; D051381:Rats
D007545:Isoproterenol; D001241:Aspirin; D002118:Calcium
Ruolo delle piastrine nell'infarto miocardico da isoproterenolo nel ratto.