[Biliary lithiasis in cystic fibrosis. Study of the bile salts in the serum and in the bile in one case (author's transl)].
Biliary lithiasis was discovered in a girl aged 11 suffering from Cystic Fibrosis and who underwent partial small bowel resection for meconium ileus. A cholecystectomy was performed at 15. Examination of the stones showed that they were composed of cholesterol and chemical examination of the bile showed an increase of phospholipids and a decrease in bile salts. There was also a modification of the ratio (Formula: see text) in the serum and the bile. All those factors contribute to the insolubility of cholesterol and to the formation of lithiasis. For all those reasons, the authors recommend a regular radiologic surveillance of the gallbladder in Cystic Fibrosis.
D000293:Adolescent; D001646:Bile / Q000032:analysis*; D001647:Bile Acids and Salts / Q000032:analysis* / Q000097:blood; D002648:Child; D002763:Cholecystectomy; D002769:Cholelithiasis / Q000209:etiology* / Q000378:metabolism / Q000628:therapy; D002784:Cholesterol / Q000032:analysis; D003550:Cystic Fibrosis / Q000150:complications* / Q000378:metabolism; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007415:Intestinal Obstruction / Q000601:surgery; D007421:Intestine, Small / Q000601:surgery
D001647:Bile Acids and Salts; D002784:Cholesterol
Lithiase biliaire au cours de la mucoviscidose. Etude des sels biliaires dans le sérum et la bile chez une malade.