title: [Comparative, quantitative and morphological investigations (automatic image analysis--micromorphometric analysis) of myocardium of rat isoprenalin treatment (author's transl)].
abstract: The alterations of areas of myocardium of male rats (2, 4, and 6 months) are investigated after isoprenalin treatment (0.05 mg/kg body weight and day i.p. for 30 days). The investigations are carried out using automatic microscope picture analysis, morphometric point counting and resp. Both methods yield the same qualitative results: The effect of isoprenalin is dependent on age and yields for old rats (6 months) only very little morphometric alterations in the myocardium. The automatic microscope picture analysis is a very effective method of investigation (45 seconds/cross section).
mesh_terms: D000367:Age Factors; D000818:Animals; D003201:Computers; D006321:Heart / Q000187:drug effects*; D007545:Isoproterenol / Q000494:pharmacology*; D008297:Male; D009206:Myocardium / Q000473:pathology; D051381:Rats
chemical_list: D007545:Isoproterenol
vernacular_title: Vergleichende quantitativ-morphologische Untersuchungen (Automatische Mikroskopbildanalyse--mikromorphometrische Analyse) des Myokards der Ratte nach wiederholten Gaben von Isoprenalin.