A toxin purified from the venom of black widow spider affects the uptake and release of radioactive gamma-amino butyrate and N-epinephrine from rat brain synaptosomes.
D000818:Animals; D001180:Arthropod Venoms / Q000494:pharmacology*; D001692:Biological Transport / Q000187:drug effects; D001740:Black Widow Spider; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D004837:Epinephrine / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D008297:Male; D051381:Rats; D013111:Spider Venoms / Q000302:isolation & purification / Q000494:pharmacology*; D013574:Synaptosomes / Q000187:drug effects / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D001180:Arthropod Venoms; D013111:Spider Venoms; D005680:gamma-Aminobutyric Acid; D004837:Epinephrine