Effect of random airway sizes on aerosol deposition.
A previously developed deposition model is used to determine the total and regional deposition of inhaled aerosols in a population of human lungs by taking into account variability in airway dimensions. The results for particle sizes ranging from 0.1 micron to 8 micron aerodynamic diameter agree favorably with experimental data, thus suggesting that observed intersubject deposition variability is caused primarily by difference in airway dimensions.
D000336:Aerosols / Q000009:adverse effects*; D006801:Humans; D008168:Lung / Q000033:anatomy & histology*; D008433:Mathematics; D008954:Models, Biological; D010316:Particle Size
D000336:Aerosols