[Effect of fat free diet during the last week of pregnancy upon the linoleic and arachidonic acid content of fetal organ lipids and placenta lipids of the rat].
Pregnant Wistar rats were fed a fatfree diet from day 16--22 of pregnancy. On day 22, the fatty acid components of cholesterol esters, triglycerides, free fatty acids and phospholipids of maternal (brain, muscle, serum, white adipose tissue, liver) and fetal (brain, carcass, serum, liver) tissues, including the placenta, were examined gaschromatographically for the participation of linoleic and arachidonic  acid. In all fetal and maternal organs the linoleic acid levels in the fatty acid patterns were strongly reduced. The alterations nearly always involved all the lipid fractions of a tissue and were mostly equal within a tissue. The strongest decreases of linoleic acid occurred in the placenta, and the weakest, in the lipids of maternal muscle and maternal adipose tissue. The linoleic acid alterations were principally similar in fetal and the corresponding maternal tissues, while being less pronounced in case of maternal muscle. The participation of arachidonic acid in the fatty acid pattern is completely retained in the lipids of fetal organs, and is even enhanced in those of the placenta.
D000818:Animals; D001095:Arachidonic Acids / Q000032:analysis*; D002788:Cholesterol Esters / Q000032:analysis; D004041:Dietary Fats; D005230:Fatty Acids, Nonesterified / Q000032:analysis; D005260:Female; D005333:Fetus / Q000378:metabolism; D008041:Linoleic Acids / Q000032:analysis*; D050356:Lipid Metabolism; D008431:Maternal-Fetal Exchange; D010743:Phospholipids / Q000032:analysis; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D011270:Pregnancy, Animal; D051381:Rats; D014018:Tissue Distribution; D014280:Triglycerides / Q000032:analysis
D001095:Arachidonic Acids; D002788:Cholesterol Esters; D004041:Dietary Fats; D005230:Fatty Acids, Nonesterified; D008041:Linoleic Acids; D010743:Phospholipids; D014280:Triglycerides
Der Einfluss fettfreier Diät während der letzten Schwangerschaftswoche auf den Linol- und Arachidonsäuregehalt der Organlipide des Feten und der Plazentalipide der Ratte.