title: Pathogenicity of some Mycoplasma and Acholeplasma species in the lungs of gnotobiotic calves.
abstract: Cloned cultures of 16 strains, representing nine different species of Mycoplasma and Acholeplasma, were inoculated intratracheally into gnotobiotic calves. Strains of M bovirhinis, M canadense, M verecundum, A axanthum and A modicum did not produce visible pneumonic lesions and were not reisolated from the lungs. Strains of M alkalescens and M arginini colonised the lower respiratory tract but failed to produce visible pneumonia. M bovigenitalium (strain M991/70) and M dispar (strain Gri226) both colonised the respiratory tract and induced pneumonic lesions estimated to involve up to 8 per cent (M bovigenitalium) and 17 per cent (M dispar) of the lung. Histologically M bovigenitalium produced a cuffing pneumonia and M dispar produced a interstitial alveolitis.
mesh_terms: D000127:Acholeplasma / Q000302:isolation & purification / Q000472:pathogenicity*; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000209:etiology* / Q000382:microbiology; D005856:Germ-Free Life; D008168:Lung / Q000382:microbiology; D009174:Mycoplasma / Q000302:isolation & purification / Q000472:pathogenicity*; D009175:Mycoplasma Infections / Q000209:etiology / Q000382:microbiology / Q000662:veterinary*; D011014:Pneumonia / Q000209:etiology / Q000382:microbiology / Q000662:veterinary*