title: Necessity for end colostomy with transection of the descending colon in guinea pigs.
abstract: Surgical procedures for resection and transection of the descending colon in the guinea pig were studied. Wedge resection with removal of less than 1 cm diameter of tissue resulted in an 80% (8 of 10 guinea pigs) survival rate. Colonic transection with restorative anastomosis, either end-to-end or side-to-side, resulted in a 94% (35 of 37 guinea pigs) death rate due to colonic impaction proximal to the site of anastomosis. A modified procedure for ventral end colostomy resulted in a 79% (19 of 24 guinea pigs) survival rate. These results indicated that caution should be taken in surgical manipulations intended to treat or study diseases of the colon in the guinea pig.
mesh_terms: D000818:Animals; D003108:Colonic Diseases / Q000601:surgery / Q000662:veterinary; D003125:Colostomy / Q000662:veterinary*; D006168:Guinea Pigs / Q000601:surgery*