Cholestyramine in the peritoneal cavity of the rat.
The effects of cholestyramine in the peritoneal cavity of the rat are described. Cholestyramine causes mild peritonitis with adhesion formation between the liver and the omentum. In the management of biliary peritonitis, a lavage solution containing a suspension of cholestyramine would appear to be contra-indicated by these experimental studies.
D000818:Animals; D056486:Chemical and Drug Induced Liver Injury; D002792:Cholestyramine Resin / Q000633:toxicity*; D005260:Female; D008107:Liver Diseases / Q000473:pathology; D009852:Omentum / Q000473:pathology; D010537:Peritoneum / Q000473:pathology; D010538:Peritonitis / Q000139:chemically induced* / Q000473:pathology; D051381:Rats; D000267:Tissue Adhesions
D002792:Cholestyramine Resin