title: Intra-incisional cephaloridine: a comparison of two methods of administration.
abstract: Serum cephaloridine concentrations were measured in the immediate post-operative period in 23 patients who had received a prophylactic dose of 1 g of the drug into the wound at the end of operation. Eleven patients received the antibiotic as a powder and 12 as a solution. The serum concentrations were higher, though not significantly so, in the group receiving powder, and this is thought to be due to the lesser amount of spillage and loss into dressings when the antibiotic is given in this form.
mesh_terms: D002509:Cephaloridine / Q000008:administration & dosage* / Q000097:blood / Q000627:therapeutic use; D006801:Humans; D011208:Powders; D012996:Solutions; D013530:Surgical Wound Infection / Q000517:prevention & control*; D013997:Time Factors
chemical_list: D011208:Powders; D012996:Solutions; D002509:Cephaloridine