Ophthalmoplegia, ataxia and hyporeflexia (Fisher's syndrome). With a midbrain lesion demonstrated by CT scanning.
This report concerns a patient with ophthalmoplegia, ataxia and hyporeflexia (Fisher's syndrome) with a lesion in the midbrain tegmentum demonstrated by computerized-tomography (CT) scanning. Spontaneous recovery was almost complete 1 month after the onset. Based upon its strategic location, it is suggested that the lesion can explain the findings in the patient. The CT finding, if confirmed, will necessitate a reconsideration of our current pathogenetic views about Landry-Guillain-Barré syndrome in general and Fisher's syndrome in particular.
D001259:Ataxia / Q000209:etiology*; D001927:Brain Diseases / Q000503:physiopathology; D002648:Child; D005260:Female; D006801:Humans; D008636:Mesencephalon / Q000473:pathology; D009886:Ophthalmoplegia / Q000209:etiology*; D011129:Polyradiculoneuropathy / Q000000981:diagnostic imaging*; D012021:Reflex, Abnormal / Q000209:etiology*; D013681:Tegmentum Mesencephali / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed