title: Degeneration and regeneration of some mechanoreceptors. An ultrastructural study. I. Ultrastructure of denervated Herbst corpusles.
abstract: The degenerative changes in the HERBST corpusles have been investigated at ultrastructural level during the 3rd h to 1 year after nerve section. The earliest changes have been established in the nerve ending followed by the remaining nonmyelinated and myelinated portion of the receptor nerve fibre. The changes reflect the retrograde character of the degenerative process. The receptor cell elements pass through the stage of activation followed by their destruction and elimination. The Schwann receptor cells fullfill the pagocytotic role in the elimination of the axonal debris, after that they have been also completely eliminated. Their places are occupied by the activated fibroblasts and developed collagen fibrils. One part of the perineural cells persist a long time after denervation and they preserve the common although modified receptor configuration.
mesh_terms: D000818:Animals; D003714:Denervation; D004372:Ducks / Q000033:anatomy & histology*; D007365:Intercellular Junctions / Q000648:ultrastructure; D008465:Mechanoreceptors / Q000648:ultrastructure*; D008938:Mitosis; D009186:Myelin Sheath / Q000648:ultrastructure; D009410:Nerve Degeneration; D009412:Nerve Fibers / Q000648:ultrastructure; D009416:Nerve Regeneration; D009940:Organoids / Q000648:ultrastructure; D012583:Schwann Cells; D012867:Skin / Q000294:innervation*; D013997:Time Factors