New antibiotic pigments related to fusarubin from Fusarium solani (Mart.) Sacc. I. Fermentation, isolation, and antimicrobial activities.
A cholesterol-decomposing fungus, Fusarium solani (Mart.) SACC. strain PP 96, was found to produce several different naphthaquinone pigments in a glycerol-mineral salts medium. Three novel compounds structurally related to fusarubin were isolated by chloroform extration followed by silicic acid column chromatography and preparative thin-layer chromatography. The purified compounds were found to have relatively low activity against bacteria, yeasts and filamentous fungi.
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D004352:Drug Resistance, Microbial; D005285:Fermentation; D005670:Fusarium / Q000378:metabolism*; D009285:Naphthoquinones / Q000302:isolation & purification* / Q000494:pharmacology; D010860:Pigments, Biological / Q000302:isolation & purification* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D009285:Naphthoquinones; D010860:Pigments, Biological