Pulsed nuclear magnetic resonance studies on nuclear fractions of normal and malignant tissues.
Nuclear fractions isolated from normal liver tissues and an experimental tumor--mouse fibrosarcoma (MFS)--were studied by pulsed NMR. Findings were: (1) T1 values of nuclear fractions are higher than those of the tissues or origin. (2) T1 values of nuclear fractions isolated from liver of tumor-bearers are higher than T1 values of nuclear fractions of normal liver. (3) T1 values of nuclear fractions of MFS tumor are higher than nuclear fractions of liver of tumor-bearing mice. Comparison of T1 values of the nuclear fractions shows a hierarchy of T1 from liver to MFS.
D000818:Animals; D001834:Body Water / Q000032:analysis; D002467:Cell Nucleus / Q000032:analysis*; D005354:Fibrosarcoma / Q000032:analysis*; D008099:Liver / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D009374:Neoplasms, Experimental / Q000032:analysis