[Leydig cell tumor of the ovary (biologic (in vivo and in vitro) and ultrastructural study) (author's transl)].
The authors present the case of a young hirsute woman of 28 years old. Urinary 17 KS were very increased without DHA, but with androsterone, etiocholanolone and 11 oxy 17 Ketosteroids. Androstenedione and testosterone plasmatic levels were very high and per operative selective ovarian vein catheterization showed a direct production of these potent androgens. In vitro study of the tumor allowed to obtain same results. Light and electron microscopic study showed a Leydig cell tumor of left ovary.
D015068:17-Ketosteroids / Q000652:urine; D000328:Adult; D000735:Androstenedione / Q000097:blood; D005260:Female; D006628:Hirsutism / Q000378:metabolism*; D006801:Humans; D007984:Leydig Cell Tumor / Q000378:metabolism* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000378:metabolism* / Q000473:pathology; D013739:Testosterone / Q000097:blood
D015068:17-Ketosteroids; D013739:Testosterone; D000735:Androstenedione
Tumeur ovarienne à cellule de Leydig. Etude biologique (in vivo et in vitro) et ultrastructurale.