[Lupus erythematosus panniculitis (author's transl)].
Lupus erythematosus panniculitis is a rare clinical variant of lupus erythematosus. In this report we described a 38 year-old female patient who had suffered from chronic discoid lupus erythematosus for several years before developing widespread inflammatory, sclerotic and ulcerative lesions, which were first diagnosed as Weber-Christian panniculitis. It was only when the patient developed other signs and symptoms of systemic lupus erythematosus that the subcutaneous lesions were recognized as lupus panniculitis. A combined regimen of tetracyclines and chloroquine resulted in a remission, both with regard to regression of the lesions and suppression of the serological parameters of disease activity. The findings in this particular patient and similar reports in the literature form the basis for a discussion of the entity of lupus panniculitis.
D002738:Chloroquine / Q000627:therapeutic use; D003176:Complement C3 / Q000032:analysis; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D008179:Lupus Erythematosus, Discoid / Q000150:complications* / Q000188:drug therapy; D008775:Methylprednisolone / Q000627:therapeutic use; D010201:Panniculitis, Nodular Nonsuppurative / Q000150:complications*; D012867:Skin / Q000276:immunology; D013752:Tetracycline / Q000627:therapeutic use
D003176:Complement C3; D007075:Immunoglobulin M; D002738:Chloroquine; D003520:Cyclophosphamide; D013752:Tetracycline; D008775:Methylprednisolone
Lupus-erythematosus-Pannikulitis.