Sulfones and sulfonamides in dermatology today.
Although dapsone and sulfapyridine have been used for years in dermatology, there has not always been a clear understanding of how these agents work. Recent investigation, however, has shed new light on thes agents which now allows a more rational approach to their use. This review is an attempt to familiarize the clinician with how these agents work, in what disease states they are effective, how to administer them, what adverse effects may occur, and how to monitor the patient to detect these adverse effects.
D000380:Agranulocytosis / Q000139:chemically induced; D003622:Dapsone / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D004342:Drug Hypersensitivity / Q000209:etiology; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced; D008708:Methemoglobinemia / Q000139:chemically induced; D012871:Skin Diseases / Q000188:drug therapy*; D013424:Sulfanilamides / Q000627:therapeutic use*; D013427:Sulfapyridine / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D013577:Syndrome
D013424:Sulfanilamides; D003622:Dapsone; D013427:Sulfapyridine