Potential fungicidal and bactericidal agents. Synthesis of certain 4-(2-amino-1,3,4-thiadiazol-5-yl)quinolines.
The synthesis of some new 4-[2-alkyl (aryl or aralkyl) amino-1,3,4-thiadiazol-5-yl]-2-substituted quinolines is described. IR, UV, NMR and MS data of representative examples are discussed. Most of the compounds prepared showed a reasonable antifungal and antimicrobial activity.
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D000935:Antifungal Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D011804:Quinolines