Effect of nutrient variations on growth and brefeldin A formation in Curvularia lunata.
The highest level of secreted brefeldin A was present in glucose-grown cultures, intermediate levels in glucose-fructose, and xylose cultures and low levels in fructose- and galactose-grown cultures of Curvularia lunata. The biomass decreased from glucose, fructose, xylose, glucose-fructose to galactose cultures. Brefeldin A levels and mycelial yields were low in citrate-, gluconate-, and succinate-grown cultures. Inorganic phosphate-limited cultures supported a high level of brefeldin A. Intermediate levels were present in trace elements-, and inorganic phosphate-trace elements-limited cultures.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D003470:Culture Media; D003517:Cyclopentanes / Q000096:biosynthesis; D005632:Fructose / Q000378:metabolism; D005690:Galactose / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D003904:Mitosporic Fungi / Q000254:growth & development / Q000378:metabolism*; D010461:Peptones / Q000378:metabolism; D010710:Phosphates / Q000378:metabolism; D014131:Trace Elements / Q000378:metabolism; D014994:Xylose / Q000378:metabolism
D000900:Anti-Bacterial Agents; D003470:Culture Media; D003517:Cyclopentanes; D010461:Peptones; D010710:Phosphates; D014131:Trace Elements; D005632:Fructose; D014994:Xylose; D005947:Glucose; D005690:Galactose