Studies on the mechanism of post-etorphine catalepsy. Modyfying effect of amphetamine, apomorphine and dihydroxy-phenylalanine (L-dopa) on etorphine-induced concentrations of dopamine and noradrenaline in the rat central nervous system.
Studies on the mechanism of post-etorphine catalepsy. Modyfying of amphetamine, apomorphine and dihydroxyphenyl-alanine (L-DOPA) on etorphine-induced concentrations of dopamine and noradrenaline in the rat central nervous system. Acta Physiol. Pol., 1979, 30 (2): 279--287. During stereotypy induced with amphetamine, apomorphine and 1-dihydroxyphenylalanine (L-DOPA) increased concentrations of dopamine (DA) and noradrenaline (NA) were found in the motor centres of the central nervous system (CNS). In post-etorphine catalepsy the concentrations of DA and NA were also increased in the frontal cortex, striopallidum, pons and cerebellum and in the lumbosacral spinal cord. However, these stereotypy-inducing agents used in premedication of post-etorphine catalepsy delayed significantly its onset and reduced its duration.
D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D001923:Brain Chemistry; D002375:Catalepsy / Q000503:physiopathology*; D004298:Dopamine / Q000032:analysis*; D005048:Etorphine / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D006801:Humans; D007980:Levodopa / Q000494:pharmacology*; D008297:Male; D009019:Morphinans / Q000037:antagonists & inhibitors*; D009638:Norepinephrine / Q000032:analysis*; D051381:Rats
D009019:Morphinans; D005048:Etorphine; D007980:Levodopa; D000661:Amphetamine; D001058:Apomorphine; D004298:Dopamine; D009638:Norepinephrine