Sugar-specific antibodies reactive towards cell-surface carbohydrates.
Antibodies generated against sugar-azoproteins have been purified by affinity chromatography using elution with monosaccharide. They have high specificity for monosaccharide and they react with terminal, non-reducing sugars on the surfaces of human erythrocytes. Some of them, either native or as Fab fragments, inhibit mitogenic stimulation of lymphocytes by concanavalin A.
D000818:Animals; D000906:Antibodies / Q000302:isolation & purification; D000917:Antibody Formation; D000918:Antibody Specificity; D002241:Carbohydrates / Q000276:immunology*; D004910:Erythrocyte Membrane / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology*; D006384:Hemagglutination; D006801:Humans; D066298:In Vitro Techniques; D008214:Lymphocytes; D008934:Mitogens; D011817:Rabbits / Q000276:immunology
D000906:Antibodies; D002241:Carbohydrates; D008934:Mitogens