title: Stress-generated potentials in bone: effects of collagen modifications.
abstract: The effect of collagen modification on the magnitude of stress-generated potentials has been studied. A whole bone model has been developed for determining the effects of collagen crosslinking on the electrical signals. Increased crosslinking results in larger electrical signals, and such increases result whether in vivo or in vitro changes in the collagen are made.
mesh_terms: D000375:Aging; D000629:Aminopropionitrile / Q000494:pharmacology; D000818:Animals; D001842:Bone and Bones / Q000187:drug effects; D003094:Collagen; D004560:Electricity; D005557:Formaldehyde / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D008954:Models, Biological; D051381:Rats; D013314:Stress, Mechanical
chemical_list: D000629:Aminopropionitrile; D005557:Formaldehyde; D003094:Collagen