[Antibody treatment of digoxin intoxication in a patient with renal failure (author's transl)].
A 72-year-old man with coronary heart disease and renal failure required hospitalization because of digoxin intoxication with severe arrhythmias and generalised heart failure. The intoxication was successfully treated and sinus rhythm rapidly restored after administration of heterologous digoxin-specific F(ab')2 antibody fragments. There were no side-effects and the heart failure improved after treatment.
D000368:Aged; D000818:Animals; D000906:Antibodies; D003327:Coronary Disease / Q000188:drug therapy; D004077:Digoxin / Q000506:poisoning*; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D012756:Sheep / Q000276:immunology
D000906:Antibodies; D004077:Digoxin
Antikörperbehandlung einer Digoxin-Intoxikation bei einem Patienten mit Niereninsuffizienz.