[Clinical and laboratory chemical examination in the diagnostic demarkation of chronic lymphatic leukemia].
In its conventional meaning, chronic lymphatic leukemia (CLL) describes a variety of clinical and prognostical aspects. Since it was found using immunohistological methods that a remarkable number of lymphoplasmacytoid lymphoma (immunocytoma) were initially considered to belong to the CLL-group according to cell morphology, cell count and clinical status, the purpose of this study was to set up clinical and laboratory parameters separating CLL and immunocytoma. This was accomplished by categorizing 71 patients of preliminary CLL by age, sex, distribution of B and T lymphocytes, cell morphology, symptoms at the time of diagnosis, clinical course, electrophoresis and quantitative immunoglobulines. According to these features, the sample of patients was divided into three groups: Group 1: chronic lymphatic leukemia probable. Group 2: immunocytoma probable. Group 3: clear-cut separation is not possible. In these patients a lymphnode extirpation and a fluorescent examination of surface immunoglobulines should be performed.
D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007945:Leukemia, Lymphoid / Q000175:diagnosis* / Q000276:immunology; D008223:Lymphoma / Q000175:diagnosis / Q000276:immunology; D008297:Male; D008875:Middle Aged
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Klinische und laborchemische Untersuchungen zur diagnostischen Abgrenzung der chronischen lymphatischen Leukämie.