Evidence of a long-term rhythm in withdrawal, brain concentration, and hepatic clearance of morphine in the rat.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D004343:Drug Implants; D005260:Female; D006801:Humans; D008099:Liver / Q000378:metabolism*; D008297:Male; D009020:Morphine / Q000097:blood / Q000378:metabolism*; D009021:Morphine Dependence / Q000188:drug therapy / Q000378:metabolism*; D009270:Naloxone / Q000627:therapeutic use; D051381:Rats; D012621:Seasons; D012737:Sex Factors; D013375:Substance Withdrawal Syndrome / Q000378:metabolism*; D013997:Time Factors
D004343:Drug Implants; D009270:Naloxone; D009020:Morphine