Computerised tomography in the leucodystrophies.
11 patients with a diagnosis of leucodystrophy are reported. In 9 the CAT scan was abnormal and showed areas of markedly decreased density in the white matter. 3 of these patients had adrenoleucodystrophy. In 2, contrast enhancement at the anterior borders of the low density areas was present. The 2 negative scans were from children with metachromatic leucodystrophy; one had an atypical form of the disease and the other had the biochemical defect, but was still presymptomatic and had no neurological deficit.
D000293:Adolescent; D001921:Brain / Q000000981:diagnostic imaging*; D002675:Child, Preschool; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007966:Leukodystrophy, Metachromatic / Q000000981:diagnostic imaging; D008297:Male; D014057:Tomography, X-Ray Computed