title: [Serum alkaline phosphatase and transaminase activity in cows with clinical ketosis].
abstract: Studied was the activity of the alkaline phosphatase and the transaminases in the serum of clinically normal and ketosis-affected cows as well as cows with an affected liver. The changes were followed in the activity of SGOT and SGPT that had set in as a result of five-day starving and the injection of prednisolon at the rate of 0.5 mg/kg in the course of four days. The activity of serum alkaline phosphatase in ketosis-affected cows proved unchanged--1.99 +/1 0.35 VE. A moderate increase was established in cows with liver affections-- 3.73 +/- 0.35 VE. The hyperenzymemia in ketosis-affected animals, in animals with liver injuries as well as in cows subjected to starving or prednisolon treatment was substantiated by the higher activity of SGOT. Dependable higher values of SGOT were established in the serum of freshly calved cows as compared to cows of advanced lactation. The higher activity of SGOT in animals with ketosis is associated with the physiologic status, starving, enzyme induction, inadequacy of the cell energy balance--all limiting the possibility of it being ascribed with preference to the tissue proliferation or destruction, which is to be expected with cows having an affected liver.
mesh_terms: D000138:Acidosis / Q000662:veterinary*; D000410:Alanine Transaminase / Q000097:blood*; D000469:Alkaline Phosphatase / Q000097:blood*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood*; D002417:Cattle; D002418:Cattle Diseases / Q000201:enzymology*; D005260:Female; D007662:Ketosis / Q000150:complications / Q000201:enzymology / Q000662:veterinary*; D007774:Lactation; D008107:Liver Diseases / Q000150:complications / Q000662:veterinary; D011239:Prednisolone / Q000494:pharmacology; D011247:Pregnancy; D013217:Starvation
chemical_list: D011239:Prednisolone; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase
vernacular_title: Serumnata aktivnost na alkalnata fosfataza i transaminazite pri kravi s klinichna ketoza.