title: "Prostatic acid phosphatase?" A comparison of acid phosphatase activities in epithelial cells, granulocytes, monocytes, lymphocytes, and platelets purified by velocity sedimentation in isokinetic gradients of Ficoll in tissue culture medium.
abstract: Numerous investigators have found several substrates and inhibitors to be particularly suited for the demonstration of acid phosphatase of prostatic origin. There has been much controversy over the specificity or lack of specificity of several substrates and inhibitors. We have investigated acid phosphatase activities obtained from several kinds of purified cells. None of the substrates or inhibitors which we studied permitted us to discriminate "prostatic" acid phosphatase from acid phosphatase activities obtained from other kinds of cells.
mesh_terms: D000135:Acid Phosphatase / Q000037:antagonists & inhibitors / Q000302:isolation & purification*; D001792:Blood Platelets / Q000201:enzymology; D003300:Copper / Q000494:pharmacology; D004847:Epithelial Cells; D004848:Epithelium / Q000201:enzymology; D005459:Fluorides / Q000494:pharmacology; D005557:Formaldehyde / Q000494:pharmacology; D006098:Granulocytes / Q000201:enzymology; D006358:Hot Temperature; D006801:Humans; D007501:Iron / Q000494:pharmacology; D008214:Lymphocytes / Q000201:enzymology; D008297:Male; D009000:Monocytes / Q000201:enzymology; D010710:Phosphates; D010767:Phosphorylcholine; D011467:Prostate / Q000201:enzymology*; D011471:Prostatic Neoplasms / Q000175:diagnosis; D013644:Tartrates / Q000494:pharmacology
chemical_list: D010710:Phosphates; D013644:Tartrates; D010767:Phosphorylcholine; D005557:Formaldehyde; D003300:Copper; D007501:Iron; D000135:Acid Phosphatase; D005459:Fluorides