Establishment of an albino sand rat (Psammomys obesus colony and comparison with the natural coloured animal.
The lifespan and fertility of albino sand rats were found to be severely reduced in comparison with a laboratory colony of brown sand rats. The albinos were also much more susceptible to diabetes, as judged by their glucose tolerance. In fact, untreated albinos had a higher incidence of diabetic response than coloured sand rats fed a diabetogenic diet. The albino sand rats reproduced poorly because of a reduction in male fertility. Circulating testosterone levels and seminal vesicle weights were reduced in the albinos. It is speculated that the reduction in reproductive capacity is related to diabetes.
D000417:Albinism; D000818:Animals; D003920:Diabetes Mellitus / Q000662:veterinary; D005260:Female; D005298:Fertility; D006029:Glycosuria / Q000662:veterinary; D006200:Hair Color; D008098:Litter Size; D008297:Male; D011247:Pregnancy; D051381:Rats / Q000502:physiology*; D012376:Rodent Diseases; D012621:Seasons