title: ["Late onset disease" (congenital german measles) (author's transl)].
abstract: The paper reports on a case of "late onset disease" (congenital German measles). Diagnostically significant for this disease in an infant appearing perfectly healthy when new-born, were mainly the findings of an interstitial pneumonia, hepatosplenomegaly, as well as findings indicating the presence of a meningoencephalitis and retinopathy. The diagnosis of this rare course of congenital German measles was finally established via the identification of specific IgM rubeola antibodies, of a raised hemagglutination inhibition titer, and of the German measles virus itself. An attempt to treat the interstitial pneumonia with cortisone preparations remained unsuccessful. The clinical and diagnostic problem complexes are discussed briefly.
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D006385:Hemagglutination Inhibition Tests; D006529:Hepatomegaly / Q000175:diagnosis; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007223:Infant; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis; D011658:Pulmonary Fibrosis / Q000175:diagnosis; D012164:Retinal Diseases / Q000175:diagnosis; D012409:Rubella / Q000151:congenital* / Q000175:diagnosis; D013163:Splenomegaly / Q000175:diagnosis; D013997:Time Factors
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M
vernacular_title: Angeborene Röteln mit spätem Krankheitsbeginn ("Late onset disease").