[Brain sulfatides and cerebrosides in experimental hyperphenylalaninemia].
Effect of acute and chronic hyperphenylalaninemia (HPA) on metabolism of various fractions of sulfatides and cerebrosides from rat brain was studied. Content of all the fractions was distinctly decreased under the effect of HPA. The specific radioactivity in the majority of the sulfatide and cerebroside fractions decreased more significantly in chronic HPA. The data obtained suggest that synthesis of sulfatides and cerebrosides was inhibited in experimental hyperphenylalaninemia.
D000208:Acute Disease; D000818:Animals; D001921:Brain / Q000378:metabolism*; D002554:Cerebrosides / Q000378:metabolism*; D002908:Chronic Disease; D004195:Disease Models, Animal; D006801:Humans; D050356:Lipid Metabolism; D010649:Phenylalanine / Q000097:blood*; D010661:Phenylketonurias / Q000378:metabolism; D051381:Rats; D013433:Sulfoglycosphingolipids / Q000378:metabolism*
D002554:Cerebrosides; D013433:Sulfoglycosphingolipids; D010649:Phenylalanine
Issledovanie sul'fatidov i tserebrozidov golovnogo mozga pri éksperimental'noĭ giperfenilalaninemii.