[The manufacture and transfusion of deep frozen preserved blood].
For the past ten years we have been evaluating the preservation of human red cells by freezing. A comparative study of several techniques revealed no major differences as far as clinical effectiveness is concerned. The recovery percentage varies from 90-95%. Due to the washing procedure, necessary for removing the intracellular cryophylactic substance glycerol, no side effects from these ghosts have been observed. The maximum storage time in the post-thaw period should not exceed 24 hours, because the so-called "closed system" is interrupted. Since the preparations and storage of these cells is laborious and expensive, frozen blood should be used in selected clinical situations, i.e. rare blood types, autologous transfusions.
D001793:Blood Preservation; D001804:Blood Transfusion, Autologous; D003451:Cryoprotective Agents; D005615:Freezing; D005990:Glycerol; D006505:Hepatitis / Q000635:transmission; D006801:Humans
D003451:Cryoprotective Agents; D005990:Glycerol
Herstellung und Transfusion von tiefgekühlten Blutkonserven