Survival following thrombotic thrombocytopenic purpura in pregnancy.
When thrombotic thrombocytopenic purpura (TTP) occurs in pregnancy, survival of either the mother or fetus is exceedingly rare. A patient is reported who developed this disease in the 17th week of pregnancy and recovered after treatment with antiplatelet drugs (aspirin, dipyridamole) and corticosteroids. The rationale and potential hazards of antiplatelet therapy in TTP are discussed.
D000328:Adult; D001241:Aspirin / Q000627:therapeutic use; D001780:Blood Coagulation Tests; D001803:Blood Transfusion; D001806:Blood Urea Nitrogen; D002585:Cesarean Section; D003907:Dexamethasone / Q000627:therapeutic use; D004176:Dipyridamole / Q000627:therapeutic use; D005260:Female; D005316:Fetal Distress / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000188:drug therapy / Q000401:mortality*; D011262:Pregnancy Trimester, Second; D011697:Purpura, Thrombotic Thrombocytopenic / Q000097:blood / Q000188:drug therapy / Q000401:mortality*
D004176:Dipyridamole; D003907:Dexamethasone; D001241:Aspirin