Propranolol therapy during pregnancy in a patient with idiopathic hypertrophic subaortic stenosis: is it safe?
A case is presented of a low birth weight infant born prematurely with depressed respiration, sinus bradycardia, and hypoglycemia associated with maternal propranolol therapy during pregnancy and up until labor and delivery. The need for caution in the casual use of propranolol during pregnancy in an asymptomatic patient with IHSS and the potential fetal complications are emphasized.
D000328:Adult; D001020:Aortic Stenosis, Subvalvular / Q000188:drug therapy*; D002312:Cardiomyopathy, Hypertrophic / Q000188:drug therapy*; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000187:drug effects; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*; D011433:Propranolol / Q000009:adverse effects* / Q000627:therapeutic use; D012119:Respiration / Q000187:drug effects
D011433:Propranolol