title: Consequences of experimental mitral insufficiency induced by chordotomy.
abstract: In mitral insufficiency induced by chordotomy in dogs beside the common diagnostic data the values for tissue perfusion indicative of myocardial microcirculation have been studied. Unexpectedly, a decrease of subendocardial circulation was found; this reduced circulation manifested itself with alterations such as changes in mitochondrial structure, increased quantity of subsarcolemic sarcoplasma, and degenerative symptoms.
mesh_terms: D000818:Animals; D002302:Cardiac Output; D002815:Chordae Tendineae / Q000601:surgery*; D003326:Coronary Circulation; D004285:Dogs; D006439:Hemodynamics; D008168:Lung / Q000473:pathology; D008833:Microcirculation; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D009206:Myocardium / Q000473:pathology; D013318:Stroke Volume