Experimentally induced anaplasmosis in neonatal isohemolytic anemia-recovered calves.
Anaplasma marginale infections were induced in 3 calves previously affected with neonatal immunohemolytic anemia (NIA). Similar infections were induced in 6 splenectomized and 7 intact calves. The response to infection by 3 calves (NIA recovered) closely resembled infections seen in splenectomized calves, being markedly more severe than similar infections in intact calves. Spleens from 3 (NIA recovered) calves after splenectomy were about one-tenth normal size. Marked recrudescing anaplasmal infections were not detected after splenectomy of the calves (NIA recovered), whereas marked recrudescing infections were observed after splenectomy of 2 intact calves having recovered from the primary infections.
D000712:Anaplasmosis / Q000097:blood / Q000209:etiology*; D000818:Animals; D001769:Blood / Q000382:microbiology; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood / Q000209:etiology* / Q000473:pathology; D004899:Erythroblastosis, Fetal / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006400:Hematocrit; D011247:Pregnancy; D013154:Spleen / Q000473:pathology; D013156:Splenectomy / Q000662:veterinary