title: [The use of alfatesine in the treatment of epilepsy (author's transl)].
abstract: 7 patients (aged 15 months-72 years) were treated by intravenous infusion of alfatesine in varying dose depending on age and body weight. Treatment was effective in 6 of the 7 patients, 4 of whom had previously derived no benefit from standard treatment with benzodiazepines. Intravenous injection in 2 cases only increased the interval between seizures from 3-12 minutes to 25-40 minutes. No major side-effects were observed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000530:Alfaxalone Alfadolone Mixture / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008875:Middle Aged; D011277:Pregnanediones / Q000627:therapeutic use*
chemical_list: D011277:Pregnanediones; D000530:Alfaxalone Alfadolone Mixture
vernacular_title: Effets de l'alfatésine sur l'état de mal épileptique. Rapport préliminaire.