[Signs of fetal immunology. Embryopathy caused by viruses: clinical and anatomopathological aspects. Determination of IgM and IgA in the umbilical cord blood of newborn infants in relation to intrauterine infections. Control clinical examination of infants with high levels of IgM and IgA at birth].
The Authors report the results of IgM and IgA assays in blood of the umbilical cord of 1694 newborns during the period from October 1973 to July 1974 after a rubella epidemic occurred in Piedmont. 11.67% of the newborns showed a IgM value higher than 20 mg/100 ml; 0.88% gave values higher than 40 mg/100 ml. For 3.49% IgA values were higher than 3 mg/100 ml; in 0.89% cases it was higher than 6 mg/100 ml. These newborns with high levels of IgM and IgA have been observed: the Authors conclude that there is no correlation between high levels of IgM and IgA and prenatal infection.
D005260:Female; D005312:Fetal Blood / Q000276:immunology*; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis*; D011247:Pregnancy; D012409:Rubella / Q000151:congenital / Q000175:diagnosis*
D007070:Immunoglobulin A; D007075:Immunoglobulin M
Cenni di immunologia fetale. Embriopatia da virus: quadro clinico e anatomopatologico. Dosaggio delle IgM e IgA nel sangue del cordone ombelicale di neonati in relazione alle infezioni intrauterine. Esame clinico di controllo dei bambini con elevato tasso di IgM e IgA alla nascita.