The effect of chloroquine upon the developing lens.
Applied to the developing lens of the 14-day-old chick embryo, in organ culture conditions, chloroquine prevented the elongation of the primary lens fibres, destroyed the equatorial ones and provoked vacuolisation and/or destruction in the epithelial cells.
D000818:Animals; D002642:Chick Embryo; D002738:Chloroquine / Q000494:pharmacology*; D007908:Lens, Crystalline / Q000187:drug effects / Q000196:embryology* / Q000473:pathology; D009924:Organ Culture Techniques
D002738:Chloroquine