Single case study. Amoxapine, a new antidepressant, appears in human milk.
A young woman developed galactorrhea during treatment with a new dibenzoxazepine antidepressant, amoxapine. Both amoxapine and its active and major metabolite, 8-OH-amoxapine, appeared in breast milk. More recent literature suggests that probably all antidepressants can appear in human milk.
D000328:Adult; D000657:Amoxapine / Q000009:adverse effects / Q000378:metabolism* / Q000627:therapeutic use; D001711:Biotransformation; D003863:Depression / Q000188:drug therapy; D003989:Dibenzoxazepines / Q000378:metabolism*; D005260:Female; D005687:Galactorrhea / Q000139:chemically induced; D006801:Humans; D008895:Milk, Human / Q000378:metabolism*; D011247:Pregnancy
D003989:Dibenzoxazepines; D000657:Amoxapine