title: Oestrous and ovarian responses to exogenous progesterone and oestrogen in prepubertal ewe lambs in relation to the fecundity of their dams.
abstract: Oestrus was consistently induced by 20, 40 or 80 microgram oestradiol benzoate in progesterone-primed lambs aged 23 weeks and 17 weeks respectively in two experiments. The duration of oestrus increased linearly with increasing log dose of oestrogen, and was negatively correlated with the time of its onset. In the absence of progesterone there was a reduced incidence, later onset and shorter duration of oestrus. Progesterone alone did not induce oestrus. In lambs treated during January (Exp. 2), a later date of injection of oestrogen was associated with earlier onset and longer duration of oestrus. The induced oestrus was anovulatory. Oestrogen reduced the proportion of lambs with follicles greater than or equal to 3 mm in diameter whilst progesterone had no effect. Lambs which were the progeny of low- and high-fecundity dams did not differ in their oestrous or ovarian responses. Correlations between the dam's lamb production index and the time to onset and duration of the induced oestrus were also not significant.
mesh_terms: D000818:Animals; D004958:Estradiol / Q000494:pharmacology*; D004971:Estrus / Q000187:drug effects*; D005260:Female; D005298:Fertility; D006080:Ovarian Follicle / Q000033:anatomy & histology / Q000187:drug effects*; D011247:Pregnancy; D011374:Progesterone / Q000494:pharmacology; D012756:Sheep
chemical_list: D011374:Progesterone; D004958:Estradiol