[Arginine aspartate effects on acute human alcoholizing test (author's transl)].
One oral arginine aspartate administration (10g), 30 minutes after the beginning of acute human alcoholizing test (150 ml whisky 45 degrees, 67,5 g pure alcohol, mean load about 1 g/kg), provokes the following effects. Clinically, intensity and lasting alcohol manifestations are reduced. Alcoholemic absolute curve (g/l) does not vary: 1 h peak equal in the two treated and non treated groups, similar 6 h levels but a little lesser in the treated subjects, without significative difference. Alcohol space does not vary. Arginine aspartate provokes a significant increase between 1 h and 4 h of alcoholemic disparition slope, when rapported to body weight: mg/kg/h (p < 0,02), and ethyloxydation coefficient: mg/kg/h (p < 0,05).
D000328:Adult; D004347:Drug Interactions; D000431:Ethanol / Q000097:blood* / Q000494:pharmacology; D006801:Humans; D010084:Oxidation-Reduction
D000431:Ethanol
Effets de l'aspartate d'arginine sur l'épreuve d'alcoolisation aiguë sur l'homme.