title: Biochemical and karyological properties of cells resistant to the quinazoline antifolate, methasquin.
mesh_terms: D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology*; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D002869:Chromosome Aberrations; D004351:Drug Resistance; D012696:Glycine Hydroxymethyltransferase / Q000378:metabolism; D008727:Methotrexate / Q000494:pharmacology; D008754:Methylenetetrahydrofolate Dehydrogenase (NADP) / Q000378:metabolism; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism*
chemical_list: D001224:Aspartic Acid; D013762:Tetrahydrofolate Dehydrogenase; D008754:Methylenetetrahydrofolate Dehydrogenase (NADP); D012696:Glycine Hydroxymethyltransferase; D008727:Methotrexate