[Specific cytolytic activity of human lymphocytes following vaccination with vaccinia virus and measles virus].
Human peripheral lymphocytes harvested 7 days after vaccination with vaccinia virus or measles virus lyse specifically target cells infected with the corresponding virus. This cytotoxic activity is found in a subpopulation of lymphocytes depleted of T-cells and containing lymphocytes bearing Fc receptor. The activity can also be transferred by supernatant of immune lymphocytes on addition of normal lymphocyte. These results suggest that two types of cell are involved: an antibody-secreting cell providing specific antiviral antibody (B-cells), and an effector cell bearing Fc receptor (K-cells).
D000328:Adult; D000921:Antibody-Producing Cells / Q000276:immunology; D002648:Child; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000276:immunology; D008212:Lymphocyte Depletion; D008214:Lymphocytes / Q000276:immunology*; D008457:Measles / Q000517:prevention & control; D008458:Measles Vaccine / Q000494:pharmacology*; D008459:Measles virus / Q000276:immunology*; D014615:Vaccinia / Q000517:prevention & control; D014616:Vaccinia virus / Q000276:immunology*; D014765:Viral Vaccines / Q000008:administration & dosage
D007141:Immunoglobulin Fc Fragments; D008458:Measles Vaccine; D014765:Viral Vaccines
Activité cytolytique spècifique des lymphocytes humains après vaccination par les virus de la vaccine et de la rougeole.