title: [Quantitative determination of pemoline in serum and urine after ingestion of therapeutic doses (author's transl)].
abstract: Serum and urine 5-phenyl-2-imino-4-oxazolidone (pemoline, Tradon) levels have been determined in normal subjects after therapeutic doses (40 mg). Peak levels in serum were reached within 4-6 h (1.1-1.5 mg/1). The half-life was 16-18 h. After the oral administration of 40 mg of pemoline 35-50% of the dose was excreted in urine within 32 h.
mesh_terms: D000328:Adult; D001711:Biotransformation / Q000187:drug effects; D006801:Humans; D008297:Male; D008333:Mandelic Acids / Q000652:urine; D010389:Pemoline / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism* / Q000652:urine; D013997:Time Factors
chemical_list: D008333:Mandelic Acids; D010389:Pemoline
vernacular_title: Quantitative Bestimmung von Pemolin in Serum und Harn nach Einnahme therapeutischer Dosen.