Enzymic dealkylation of a substituted aminoacetamidobenzophenone and cyclization to the corresponding benzodiazepine in vitro.
D000818:Animals; D001570:Benzodiazepinones / Q000378:metabolism*; D001577:Benzophenones / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D003500:Cyclization; D003640:Dealkylation; D004285:Dogs; D005557:Formaldehyde / Q000378:metabolism; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D010101:Oxygen Consumption; D051381:Rats; D013997:Time Factors
D001570:Benzodiazepinones; D001577:Benzophenones; D005557:Formaldehyde