[Serological recognition of agglutinins against O and H antigens of various Salmonellae in "normal" adult subjects].
The distribution of Salmonella agglutinins among 390 normal sera from people living in the district of Pisa is described, and the relation of these findings with the Salmonella serotypes occurring in the same area is discussed. Clusters of agglutinins for several O and H antigens were found at or above a titre of 1:20, in many samples. In order to explain the significance of such antibodies and their origin an identical survey was carried out on some sera from patients with chronic liver disease, using the same antigens suspensions. The results from healthy persons compared with the increased antibody titres detected in liver patients support the hypothesis that the anti-Salmonella agglutinins may be originate by various antigenic stimuli which may be specific or most frequently non-specific, since it is well established the cross-reactivity between both the somatic and flagellar antigens of Salmonella and those of other organisms.
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D000942:Antigens, Bacterial; D006801:Humans; D012475:Salmonella / Q000276:immunology; D012480:Salmonella Infections / Q000175:diagnosis*
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial
Ricognizione sierologica di agglutinine verso antigeni "O" e "H" di varie salmonelle in soggetti adulti "normali".