Galactorrhea, amenorrhea, hyperprolactinemia, and an empty sella.
Increased serum prolactin (hPRL) and increased volume of the sella turcica as detected by roentgenography are compatible with a pituitary adenoma. The empty sella syndrome can increase sella volume, but is usually associated with minimal, if any, endocrine dysfunction. The present case details a young woman with amenorrhea, galactorrhea, elevated serum hPRL, and roentgenographic evidence of an enlarged sella turcica. Pneumoencephalography with hypocycloidal polytomography is interpreted as both an empty sella, and evidence of a pituitary adenoma. The etiology and endocrine findings in the empty sella syndrome are discussed.
D000236:Adenoma / Q000150:complications; D000328:Adult; D000568:Amenorrhea / Q000150:complications*; D004652:Empty Sella Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D005687:Galactorrhea / Q000150:complications*; D006801:Humans; D007775:Lactation Disorders / Q000150:complications*; D010911:Pituitary Neoplasms / Q000150:complications; D011011:Pneumoencephalography; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*; D014056:Tomography, X-Ray
D011388:Prolactin