[Effect of long-wave ultraviolet light (313 nm) on the survivability and respiration of Candida utilis yeasts].
Irradiation of Candida utilis with near-UV (313 nm) was found to inhibit respiration; the degree of the inhibition correlated with the number of killed cells. Irradiation of the yeast mitochondria inhibited the activity of succinate oxidase; the dependence of the inhibition on the dose of near-UV (313 nm) was close to the dose dependence of the photoinhibition of respiration in whole cells. The action spectrum for the inhibition of the activity of succinate oxidase was recorded; it corresponded to the absorption spectrum of ubiquinone isolated from the yeast cells. The data obtained suggest that ubiquinone is a target molecule in the effects of inhibition of respiration and death of yeast cells induced with near-UV (313 nm).
D002175:Candida / Q000378:metabolism / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D008928:Mitochondria / Q000528:radiation effects; D010101:Oxygen Consumption / Q000528:radiation effects*; D013385:Succinate Dehydrogenase / Q000528:radiation effects; D014466:Ultraviolet Rays
D013385:Succinate Dehydrogenase
Vliianie dlinnovolnvogo ul'trafioletovogo sveta 313 nm na vyzhivaemost' i dykhanie drozhzheĭ Candida utilis.