[The implantation of lyophilized and gamma-sterilized allogenetic incus and of lyophilized and gamma-sterilized xenogenetic malleus (calf) in rabbits and humans (author's transl)].
The histological reactions to the implantation of allogenetic and xenogenetic lyophilized and gamma-sterilized material into the middle ear of rabbits and men is described. In contrary to the behaviour of allogenetic material the xenogenetic shows a clear minor tendency of revitalisation. The reason is the antigen-antibody-reaction which takes place at the capillary network of the donor and leads to a hylinosis with following obliteration of the vascular rete. Therefore the angiogenetic osteogenesis cannot develop. The clinical usuability of such material is discussed.
D000818:Animals; D001861:Bone Regeneration; D002417:Cattle; D004429:Ear Ossicles / Q000637:transplantation*; D004432:Ear, Middle / Q000098:blood supply; D005612:Freeze Drying; D006084:Graft Rejection; D006801:Humans; D007188:Incus / Q000473:pathology / Q000637:transplantation*; D008307:Malleus / Q000473:pathology / Q000637:transplantation*; D010020:Osteonecrosis / Q000473:pathology; D011183:Postoperative Complications / Q000473:pathology; D011817:Rabbits; D013242:Sterilization; D014183:Transplantation, Heterologous; D014184:Transplantation, Homologous; D014433:Tympanoplasty / Q000379:methods
Die Implantation des lyophilisierten und gamma-sterilen allogenetischen Amboss und des lyophilisierten und gamma-sterilen xenogenetischen Hammer (Kalb) bei Kaninchen und Mensch.