[Evaluation of intestinal absorption of calcium by means of double-isotope methods and oral administration of the tracer].
The percent intestinal absorption of calcium was measured in normal volunteers and in patients with idiopathic hypercalciuria employing the deconvolution method, the ratio of the two administered isotopes at equilibrium and the percent of dose present in plasma 2 hr after oral administration of the tracer. Comparison of results obtained showed that the technique based on the ratio between the two radioisotopes overestimates intestinal absorption by about 9% with respect to values calculated with the deconvolution method, but gives results comparable to those determined by oral administration of the isotope. The percent dose of the tracer 2 h after i.v. administration is closely correlated with the size of the miscible calcium pool. A less significant correlation exists between the size of the pool and percent of the dose 2 h after oral administration.
D000284:Administration, Oral; D002118:Calcium / Q000378:metabolism*; D002128:Calcium Metabolism Disorders / Q000175:diagnosis*; D002132:Calcium Radioisotopes / Q000008:administration & dosage; D006801:Humans; D007275:Injections, Intravenous; D007408:Intestinal Absorption
D002132:Calcium Radioisotopes; D002118:Calcium
Valutazione dell'assorbimento intestinale del calcio me diante i metodi del doppio isotopo e la somministrazione orale del tracciante.