title: [Bioptic liver changes in brucellosis (author's transl)].
abstract: Histomorphological changes of the liver are demonstrated in 120 biopsy samples of 104 patients with clinically and serologically proven Bang's disease. A granulomatous hepatitis was found in 1/3 of the patients in addition to a non-specific mobilisation of the active mesenchyma and a reactive hepatitis of changing intensity. The nodules are not looking like tuberculous granulomas, but consist of a disseminated accumulation of small lympho-histiocytic cells. Furthermore, the relatively high percentage of steatosis of the parenchyma (50%), lipofuscinosis (40%), and circumscribed hepatocellular siderosis (26%) can be considered as important lesions of parenchymal cells.
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D001707:Biopsy, Needle; D002007:Brucellosis, Bovine / Q000473:pathology*; D002417:Cattle; D005234:Fatty Liver / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000473:pathology; D006505:Hepatitis / Q000473:pathology; D006644:Histiocytes; D006801:Humans; D008055:Lipids / Q000032:analysis; D008062:Lipofuscin / Q000032:analysis; D008099:Liver / Q000032:analysis / Q000473:pathology*; D008107:Liver Diseases / Q000473:pathology; D008214:Lymphocytes; D008297:Male; D008875:Middle Aged; D012806:Siderosis / Q000473:pathology
chemical_list: D008055:Lipids; D008062:Lipofuscin
vernacular_title: Bioptische Leberveränderungen bei Morbus Bang.