title: Selective breeding of rats for differences in reactivity to alcohol. An approach to an animal model of alcoholism. II. Behavioral measures.
abstract: Two lines of rats have been bred which differ in sensitivity to alcohol over a range of doses, but the difference is not reflected in blood alcohol concentration, alcohol intake or selection. The two lines respond similarly on tests of emotionality; however, differences in running-wheel activity suggest differences in neural apparatus.
mesh_terms: D000428:Alcohol Drinking; D000437:Alcoholism / Q000503:physiopathology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001947:Breeding; D004195:Disease Models, Animal; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D009043:Motor Activity / Q000187:drug effects*; D051381:Rats
chemical_list: D000431:Ethanol