Alterations in blood pressure during exchange transfusion.
Blood pressure changes as a function of the rates of blood withdrawal and infusion were determined during exchange blood transfusion in 2 preterm newborn infants. 10 ml blood withdrawal and infusion completed within 3 minutes resulted in reversible changes in aortic pressure, whereas the same procedure completed within 45 to 60 seconds resulted in a progressive fall in the systolic pressure and in narrowing of the pulse pressure. In one of the cases this was associated with respiratory arrest. An exchange rate of 5 ml/kg per 3 minutes is recommended.
D001794:Blood Pressure; D004899:Erythroblastosis, Fetal / Q000628:therapy; D005078:Exchange Transfusion, Whole Blood / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000628:therapy*; D008297:Male; D011247:Pregnancy; D012131:Respiratory Insufficiency / Q000209:etiology; D013997:Time Factors