Total synthesis of prostaglandin-E2 by rearrangement of a 6,8-disubstituted-2-oxabicyclo[3.2.1]octan-3-one to a 4,5 disubstituted-perhydrocyclopenta[b]furan-2-one.
D001643:Bridged Bicyclo Compounds; D001952:Bridged-Ring Compounds; D055598:Chemical Phenomena; D002621:Chemistry; D007783:Lactones; D011458:Prostaglandins E / Q000138:chemical synthesis*
D001643:Bridged Bicyclo Compounds; D001952:Bridged-Ring Compounds; D007783:Lactones; D011458:Prostaglandins E