Lateral transport of a lipid probe and labeled proteins on a cell membrane.
Diffusion coefficients (D) of a lipid probe and labeled proteins on L-6 myoblast membranes have been measured giving D(protein) approximately 2 X 10(-10) square centimeter per second and D (lipid probe) approximately 9 X 10(-9) square centimeter per second. Some of the membrane proteins are immobile, but the lipid probe diffuses freely over macroscopic distances. Cytochalasin B slows protein but not lipid probe diffusion.
D001386:Azides / Q000494:pharmacology; D002460:Cell Line; D002462:Cell Membrane / Q000648:ultrastructure; D003078:Colchicine / Q000494:pharmacology; D003571:Cytochalasin B / Q000494:pharmacology; D003599:Cytoskeleton / Q000502:physiology; D004058:Diffusion; D066298:In Vitro Techniques; D008563:Membrane Lipids / Q000502:physiology*; D008565:Membrane Proteins / Q000502:physiology*; D013050:Spectrometry, Fluorescence
D001386:Azides; D008563:Membrane Lipids; D008565:Membrane Proteins; D003571:Cytochalasin B; D003078:Colchicine