The effect of exogenous oxytocin on luteal function in mares.
Daily injections of 150 units oxytocin administered to 6 mares on Days 4, 5, 6, 7 and 8 after ovulation (Day 0 = ovulation) failed to induced luteolysis as indicated by the maintenance of normal plasma progestagen concentrations and the occurrence of normal ovulatory intervals. Three additional mares were given oestrogen injections 24 h before an injection of oxytocin on Day 7 after ovulation, but this treatment also failed to induce luteolysis since plasma progestagen concentrations were maintained in all three mares. Two mares exhibited normal ovulatory intervals, while the third developed a corpus luteum which persisted for 46 days.
D000818:Animals; D003338:Corpus Luteum / Q000187:drug effects* / Q000502:physiology; D004054:Diethylstilbestrol / Q000494:pharmacology; D004958:Estradiol / Q000494:pharmacology; D004971:Estrus / Q000187:drug effects; D005260:Female; D006736:Horses / Q000502:physiology*; D003341:Luteolysis / Q000187:drug effects; D009215:Myometrium / Q000187:drug effects; D010121:Oxytocin / Q000494:pharmacology*; D011247:Pregnancy; D011374:Progesterone / Q000097:blood
D011374:Progesterone; D004958:Estradiol; D010121:Oxytocin; D004054:Diethylstilbestrol