Fluorescence data and studies on the lipid solubility and chemical structure of N-propyl-ajmaline as compared to ajmaline.
The quaternary N-propyl-ajmaline was found to have a higher lipid solubility than ajmaline. Lipid solubility was pH dependent. From chemical, fluorescence and IR-spectroscopic studies it is concluded that the existence of N-propyl-ajmaline in a tautomeric state between a carbinol-ammonium and an aldehyde-amine structure is responsible for the high lipid solubility.
D000404:Ajmaline / Q000031:analogs & derivatives*; D055598:Chemical Phenomena; D002621:Chemistry; D007536:Isomerism; D008055:Lipids; D012995:Solubility; D013050:Spectrometry, Fluorescence; D013055:Spectrophotometry, Infrared
D008055:Lipids; D000404:Ajmaline