[Clinical evaluation on glucocorticoid administration in neurosurgical patients (author's transl)].
Anterior pituitary function tests (ITT, TRH test and LH-RH test) were performed on 10 patients with intracranial lesions other than hypothalamo-pituitary tumors. These lesions were 8 brain tumors and 2 aneurysms. Relatively high doses of glucocorticoid were administered in pre- and post-operative period to all the cases. Preoperative study showed a slightly low response of GH and FSH in one case and a low TSH response in 2 cases. ACTH, LH and PRL were normal in all the cases. Postoperative study was performed about 10 days after ceasing of glucocorticoid. Postoperative data revealed that anterior pituitary function tests did not show any significant changes after surgeries in all the patients.
D000328:Adult; D001623:Betamethasone / Q000008:administration & dosage; D001927:Brain Diseases / Q000601:surgery*; D001932:Brain Neoplasms / Q000378:metabolism / Q000601:surgery; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D002532:Intracranial Aneurysm / Q000378:metabolism / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010908:Pituitary Hormones, Anterior / Q000378:metabolism*
D005938:Glucocorticoids; D010908:Pituitary Hormones, Anterior; D001623:Betamethasone