Mitogenic stimulation of murine spleen cells by brief exposure to Staphylococcus aureus enteroxin B.
Staphylococcal enterotoxin B rapidly and firmly attached to external membrane surfaces of C57BL/6 spleen cells and, unless neutralized by specific antitoxin, committed the spleen cells to strong blastogenic responses.
D000818:Animals; D000992:Antitoxins / Q000494:pharmacology; D001427:Bacterial Toxins / Q000494:pharmacology*; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D004768:Enterotoxins / Q000494:pharmacology*; D008213:Lymphocyte Activation / Q000187:drug effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D008938:Mitosis / Q000187:drug effects; D013154:Spleen / Q000276:immunology*; D013211:Staphylococcus aureus; D013997:Time Factors
D000992:Antitoxins; D001427:Bacterial Toxins; D004768:Enterotoxins