Quantitative histochemistry of the spinal motor neurone nucleus during human fetal development.
A quantitative histochemical study of the developing anterior horn cell nucleus was undertaken. The DNA, the arginine and lysine-rich histones as well as the acidic nuclear proteins of the spinal motor neurone nucleus were estimated during normal fetal development by means of scanning microdensitometry. The arginine-rich histones and the acidic nuclear proteins were found to be increased at the 12-14 week period, a finding which suggests that this period is critical in the differentiation of the spinal motor neurone.
D001120:Arginine / Q000032:analysis; D004247:DNA / Q000032:analysis; D005260:Female; D005865:Gestational Age; D006657:Histones / Q000032:analysis; D006801:Humans; D008239:Lysine / Q000032:analysis; D009046:Motor Neurons / Q000032:analysis*; D011247:Pregnancy; D013116:Spinal Cord / Q000032:analysis* / Q000166:cytology / Q000196:embryology*
D006657:Histones; D004247:DNA; D001120:Arginine; D008239:Lysine