[Model building in pharmacokinetics/Part II: Generalized theoretical presentation of complete integration of linear compartment models of optional structure (author's transl)].
The method of Laplace transformation is used to obtain the integral of linear differential equations for pharmacokinetic models. A general solution uniform in structure for all types of models (mammillary, catenary, mixed) was established. Choice of one more application compartments, of kinetics describing the input procedure and of elimination pathways is free.
D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010600:Pharmacology
D004364:Pharmaceutical Preparations
Modellentwicklung in der Pharmakokinetik. II. Teil: Verallgemeinerte theoretische Darstellung der vollständigen Integration linearer Kompartmentmodelle beliebiger Struktur.