Acute tubular necrosis following intravesical instillation of formalin.
Intravesical instillation of formalin in a patient with transitional cell carcinoma of the bladder and radiation cystitis was followed by acute renal failure due to acute tubular necrosis. Formic acid, which is a metabolic product of formalin, has been postulated as the pathogenetic agent responsible for acute tubular necrosis.
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000328:Adult; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy; D005557:Formaldehyde / Q000009:adverse effects* / Q000378:metabolism / Q000627:therapeutic use; D005561:Formates / Q000378:metabolism; D006801:Humans; D007683:Kidney Tubular Necrosis, Acute / Q000139:chemically induced*; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000532:radiotherapy
D005561:Formates; D005557:Formaldehyde