title: [An outbreak of "wet tail" in hamsters due to Tyzzer's organism (author's transl)].
abstract: In a colony of Golden hamsters, many animals were found to show signs of "wet tail", and spontaneous deaths occurred during two months. With this outbreak of wet tail and death, etiologic and pathologic studies were made on 11 cases supplied from the colony. Gross pathologic examination disclosed hemorrhagic enteritis in 10 and necrotic foci in the liver in 5 out of 10 cases examined. A number of bacilli morphologically suggestive of Tyzzer's organisms were detected on smears of cut surfaces of the affected intestines and livers. After inoculation with homogenate of the intestines from the moribund cases into hamsters by oral route, the same clinical manifestations as observed in spontaneous cases were reproduced, and the inoculated animals died in 10 to 14 days with numerous Tyzzer's organisms in their intestines and livers. When apparently healthy hamsters were introduced into contaminated cages with soiled bedding which were allowed to stand at room temperature for about 2 months, most of them developed signs of wet tail and died in 5 to 19 days having liver necrosis characteristic of Tyzzer's disease.
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D001424:Bacterial Infections / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary*; D001473:Bartonella / Q000472:pathogenicity*; D006224:Cricetinae; D004196:Disease Outbreaks / Q000662:veterinary*; D005260:Female; D008297:Male; D012376:Rodent Diseases / Q000453:epidemiology* / Q000635:transmission