[Splenectomy in idiopathic thrombocytopenic purpura: short- and long-term results (author's transl)].
The results of splenectomy in 25 patients with chronic idiopathic thrombocytopenic purpura (ITP) are reported. Splenectomy was performed when the platelet count was consistently less than 30,000/mm3 in spite of glucocorticoid therapy over an observation period of at least six months. Following splenectomy, 13 patients showed complete remission, 9 partial remission, whilst in 3 cases the condition was unaffected by splenectomy. It is not possible to predict a successful response to splenectomy on the basis of preoperative laboratory findings. A rise in thrombocyte count to over 400,000/mm3 during the first 2 weeks after splenectomy makes complete remission very likely.
D000293:Adolescent; D000328:Adult; D001772:Blood Cell Count; D001792:Blood Platelets; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011379:Prognosis; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000628:therapy*; D012075:Remission, Spontaneous; D013156:Splenectomy
Splenektomie bei idiopathischer thrombozytopenischer Purpura. Kurz- und Langzeitergebnisse.