Inhibitory activity of Streptococcus mitis against oral bacteria.
The antagonistic properties of three strains of Streptococcus mitis were investigated. They were found to inhibit a wide range of oral bacteria; Gram-positive and Gram-negative, facultative and anaerobic species being susceptible. The S. mitis strains were shown to be producing hydrogen peroxide, this being partially responsible for the aerobic inhibitory activity. A second inhibitory factor(s) was also produced, aerobically and anaerobically, although this could not be isolated. A limited characterization of this factor was undertaken using plate cultures.
D000191:Actinomycetaceae / Q000254:growth & development*; D000332:Aerobiosis; D000693:Anaerobiosis; D001438:Bacteroidaceae / Q000254:growth & development*; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism; D009055:Mouth / Q000382:microbiology; D013210:Staphylococcus / Q000254:growth & development*; D013291:Streptococcus / Q000254:growth & development / Q000378:metabolism*; D014678:Veillonella / Q000254:growth & development*
D006861:Hydrogen Peroxide