title: Two-step binding of eukaryotic ribosomes to brome mosaic virus RNA3.
abstract: Although brome mosaic virus RNA3 has only one translatable cistron, it can bind two 80S ribosomes at initiation. One ribosome binds at the first AUG codon (base 92-94). The other binds nearer the 5' end at an entry or holding site. Disome formation is thus unrelated to a silent cistron approximately 1,000 bases downstream.
mesh_terms: D001483:Base Sequence; D001665:Binding Sites; D002474:Cell-Free System; D003062:Codon; D009029:Mosaic Viruses / Q000235:genetics*; D009690:Nucleic Acid Conformation; D010442:Peptide Chain Initiation, Translational; D012333:RNA, Messenger / Q000378:metabolism*; D012367:RNA, Viral / Q000378:metabolism*; D012270:Ribosomes / Q000378:metabolism*
chemical_list: D003062:Codon; D012333:RNA, Messenger; D012367:RNA, Viral