Human and mouse hypoxanthine-guanine phosphoribosyltransferase: dimers and tetramers.
Human and mouse hypoxanthine-guanine phosphoribosyltransferase subunits combine to form an active heteropolymer. Dimers form the basic subunit structure of the enzymes, yet the dimers can readily associate to form tetramers. The equilibrium between dimers and tetramers is significantly influenced by the ionic strength of the enzyme solvent.
D000818:Animals; D002460:Cell Line; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D006822:Hybrid Cells / Q000201:enzymology; D007041:Hypoxanthine Phosphoribosyltransferase / Q000235:genetics; D046911:Macromolecular Substances; D051379:Mice; D008970:Molecular Weight; D011487:Protein Conformation; D014960:X Chromosome
D046911:Macromolecular Substances; D007041:Hypoxanthine Phosphoribosyltransferase