title: [Studies on the toxicity of thiaminedisulfide monoorotate. Short communication (author's transl)].
abstract: The water soluble thiaminedisulfide monoorotate (thiooratin) was studied in mice and rats for its acute and subchronic toxicity. After continuous administration over 8 weeks no organic damages, in particular no fatty livers, were found.
mesh_terms: D000818:Animals; D005260:Female; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D009963:Orotic Acid / Q000031:analogs & derivatives* / Q000633:toxicity; D013831:Thiamine / Q000031:analogs & derivatives* / Q000633:toxicity; D013997:Time Factors
chemical_list: D009963:Orotic Acid; D013831:Thiamine
vernacular_title: Untersuchungen zur Toxizität des Thiamindisulfid-monoorotat. Kurze Mitteilung.