title: [Relationship between environmental pollution and genetic monitoring of human populations].
abstract: The basis of genetic monitoring is the knowledge of laws of the spontaneous mutation process. These laws are determined for human chromosome and genome mutations by cytogenetic examination of newborns, infants with congenital defects, and the material of spontaneous abortions. Confidence intervals and all the necessary sample sizes were calculated when registering the mutagenic effects of different intensity in the general population as well as to the groups of closer contact with mutagens. Such calculations were made for controlling the spontaneous mutation process in lymphocytes of human peripheral blood on the basis of registering chromosome aberrations.
mesh_terms: D000022:Abortion, Spontaneous / Q000139:chemically induced; D000328:Adult; D000368:Aged; D002869:Chromosome Aberrations / Q000139:chemically induced; D025063:Chromosome Disorders; D004785:Environmental Pollutants / Q000633:toxicity*; D005260:Female; D005313:Fetal Death / Q000139:chemically induced; D005820:Genetic Testing; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008875:Middle Aged; D009153:Mutagens; D011159:Population Surveillance; D011247:Pregnancy
chemical_list: D004785:Environmental Pollutants; D009153:Mutagens
vernacular_title: Geneticheskiĭ monitoring populiatsiĭ cheloveka v sviazi s zagriazneniem sredy.