title: Metabolites of Dactylaria lutea. The structures of dactylariol and the antiprotozoal antibiotic dactylarin.
abstract: The metabolites of the predacious fungus Dactylaria lutea ROUTIEN include the anthraquinone macrosporin (2) and three hydroxylated 1,2,3,4-tetrahydro derivatives of this anthraquinone, altersolanol A (5), altersolanol B (4) and dactylariol (6). The structure and relative configuration of dactylariol are established from spectroscopic studies, and its absolute configuration is proposed as 1R, 2R, 3R by virtue of its co-occurrence with altersolanol B. Dactylarin, suggested by other authors to have the structure (1), is shown to be identical with altersolanol B (4).
mesh_terms: D000880:Anthraquinones / Q000096:biosynthesis*; D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D000981:Antiprotozoal Agents / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D003904:Mitosporic Fungi / Q000378:metabolism*; D008968:Molecular Conformation
chemical_list: D000880:Anthraquinones; D000900:Anti-Bacterial Agents; D000981:Antiprotozoal Agents