title: Electroanesthesia (EA) studies: current applications to human volunteers to produce general and local anesthesia.
abstract: Electrical currents found to be of sufficient intensity to produce EA in animals were applied to human subjects several hundred times, to determine whether, and how, clinical general anesthesia, and local anesthesia in various parts of the body, could be obtained. General anesthesia was not produced in any subject in any test, the obstacle in every instance being pain. Local analgesia of the arm was obtained in one subject, but in all other subjects muscle spasm and vibration pain prevented application of enough current to produce analgesia or anesthesia in the arm. Anesthesia of the hand was produced several times in all subjects, with a total loss of pain sensation.
mesh_terms: D000698:Analgesia; D000768:Anesthesia, General; D000772:Anesthesia, Local; D001132:Arm; D004566:Electrodes; D004580:Electronarcosis / Q000009:adverse effects; D005260:Female; D006225:Hand; D006801:Humans; D008297:Male; D009119:Muscle Contraction; D010146:Pain; D012535:Scalp