title: Estrogen increases both spiperone-induced catalepsy and brain levels of [3H]spiperone in the rat.
mesh_terms: D000818:Animals; D001812:Blood-Brain Barrier / Q000187:drug effects*; D001921:Brain / Q000378:metabolism; D002090:Butyrophenones / Q000378:metabolism* / Q000494:pharmacology*; D002369:Castration; D002375:Catalepsy / Q000139:chemically induced*; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D006801:Humans; D051381:Rats; D011954:Receptors, Dopamine / Q000187:drug effects; D013134:Spiperone / Q000378:metabolism* / Q000494:pharmacology*
chemical_list: D002090:Butyrophenones; D011954:Receptors, Dopamine; D004958:Estradiol; D013134:Spiperone