title: Production of carcinoembryonic antigen by human prostate epithelial cells in vitro.
abstract: The medium from all 16 human prostate epithelial cell cultures tested contained elevated levels of carcinoembryonic antigen (CEA) or CEA-like substance; 11 of 16 had greater than 20 ng CEA/ml. In contrast, medium from cultures of other human tissues (prostate fibroblasts, genitourinary tumors, melanoma, and nontumor tissue), as well as media controls, contained less than 1 ng CEA/ml. Results indicated that CEA determination may provide a way to identify human prostatic epithelium in culture.
mesh_terms: D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002478:Cells, Cultured; D004847:Epithelial Cells; D004848:Epithelium / Q000276:immunology; D006801:Humans; D008297:Male; D011467:Prostate / Q000276:immunology*; D011471:Prostatic Neoplasms / Q000276:immunology*
chemical_list: D002272:Carcinoembryonic Antigen