Oxygen consumption in the developing chick cornea.
Embryonic chick corneas at different stages of development were evaluated for O2 consumption. Some embryos were treated with thyroxine or thiouracil. In untreated animals, corneal QO2 (oxygen consumption/hr./mg. dry weight) decreased from 3.60 at stage 38 to 1.58 after hatching. The temperature coefficient Q10 increased from 1.55 at stage 40 to 2.03 after hatching. If O2 consumption is calculated as microliters of O2 consumed per hour per corneal pair, it increases between stage 38 (3.20) and hatched chicks (6.20) with a plateau between stages 40 and 45. Thiouracil treatment reduced O2 consumption by the cornea at stages 42 and 45, and thyroxine treatment elevated it at stage 40.
D000367:Age Factors; D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D002642:Chick Embryo; D003315:Cornea / Q000378:metabolism*; D010101:Oxygen Consumption / Q000187:drug effects*; D013889:Thiouracil / Q000494:pharmacology*; D013974:Thyroxine / Q000494:pharmacology*
D013889:Thiouracil; D013974:Thyroxine