title: Pancuronium reduces halothane requirement in man.
abstract: We studied the contribution of pancuronium to anesthetic requirement in man by comparing MAC for halothane alone in 18 patients, with that after intravenous administration of pancuronium, 0.1 mg/kg, in 17 patients. In each group, movement was observed in limbs isolated from the circulation by tourniquet. In patients receiving pancuronium, halothane MAC was 0.55%, whereas the control value was 0.73%. Thus pancuronium reduces halothane MAC by 25%.
mesh_terms: D000328:Adult; D000769:Anesthesia, Inhalation; D000771:Anesthesia, Intravenous; D006221:Halothane / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010197:Pancuronium / Q000494:pharmacology*
chemical_list: D010197:Pancuronium; D006221:Halothane