[Antenatal estimation of fetal maturity by exfoliative cytology of amniotic fluid (author's transl)].
In 152 amniotic fluid samples, derived either from amniocentesis or amniotomy, smears have been performed for cytological investigation (staining after Harris-Shorr). The per cent amount of different cell-shapes has been determined. Polygonal, anucleate, transparent cells, representing desquameted fetal keratinocytes, are seen more frequently in late pregnancy and have been registered separately. These data have been compared to the postnatal determination of gestational age after Dubowitz et al, as well as Farr et al. This mode of investigation allows a safe and objective determination of maturity in the last weeks of pregnancy and thereby an exclusion of a presumed fetal prematurity. This method seems very useful in differential diagnosis between fetal hypotrophy and prematurity in the latter part of pregnancy.
D000653:Amniotic Fluid / Q000166:cytology*; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D011247:Pregnancy; D011263:Pregnancy Trimester, Third
Präpartale Beurteilung der fetalen Reife durch zytologische Fruchtwasseruntersuchungen.