title: Morphology and 125I-concentration of embryonic chick thyroids cultured in an atmosphere of oxygen.
abstract: In vitro culture of whole thyroid glands may lead to loss of differentiation and function. Comparison by histology, histoautoradiography and gammacounting of 125I-concentration, of 12 to 13 days old embryonic chick thyroids, cultured on a gyratory shaker either in an atmosphere of 5% CO2 and air or of 95% O2 and 5% CO2, shows that a high concentration of O2 maintains the morphological and functional integrity of the thyroids for at least 4 days.
mesh_terms: D000818:Animals; D001274:Atmospheric Pressure; D002454:Cell Differentiation; D002642:Chick Embryo; D007457:Iodine Radioisotopes; D009924:Organ Culture Techniques; D010100:Oxygen; D013961:Thyroid Gland / Q000196:embryology* / Q000378:metabolism
chemical_list: D007457:Iodine Radioisotopes; D010100:Oxygen