Tobramycin-curare interaction.
A 59-year-old patient had urologic surgery under d-tubocurarine-fentanyl-N2O anesthesia. The muscle relaxant was reversed with prostigmine at the end of the 5-hour procedure. Reparalysis occurred after the administration of IV tobramycin and was successfully reversed with prostigmine.
D000758:Anesthesia / Q000009:adverse effects*; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D004347:Drug Interactions; D006801:Humans; D008297:Male; D008875:Middle Aged; D014031:Tobramycin / Q000009:adverse effects*; D014403:Tubocurarine / Q000009:adverse effects*
D000900:Anti-Bacterial Agents; D014031:Tobramycin; D014403:Tubocurarine