title: H-Y antigen in the teleost.
abstract: H-Y antigen, presumably the product of mammalian testis-determining genes, has been detected in three species of teleost fish, Xiphophorus maculatus. Haplochromis burtoni, and Oryzias latipes, and in hybrids of the genus Tilapia. In X. maculatus H-Y was most readily detected in YY males, suggesting that a genetic determinant of H-Y antigen expression may exist on the teleost Y-chromosome. Although H-Y was detected in males and not in feamles in each of the species that we studied, male heterogamety has not been firmly established for H. burtoni. Thus despite the extreme phlyogenetic conservation of H-Y genes and their association with the Y-chromosome, it remains open to question whether H-Y will always be found in the heterogametic sex, and whether serologically defined H-Y antigen plays any part in the differentiation of the teleost gonad.
mesh_terms: D000818:Animals; D001921:Brain / Q000276:immunology; D003429:Cross Reactions; D005260:Female; D005399:Fishes / Q000276:immunology*; D005838:Genotype; D006182:H-Y Antigen / Q000032:analysis*; D008099:Liver / Q000276:immunology; D008297:Male; D051379:Mice; D012397:Rosette Formation; D012730:Sex Chromosomes / Q000276:immunology; D012737:Sex Factors; D013045:Species Specificity; D013094:Spermatozoa / Q000276:immunology
chemical_list: D006182:H-Y Antigen