The effect of different doses of prednisolone in the treatment of childhood ITP.
The result of treatment of children with ITP, who received either 0.5, 1 or 2 mg/kg per day of prednisolone showed that 1 mg/kg per day gave the best response, the least failure rate and the duration of treatment was not different compared to 2 mg/kg per day. It was concluded that the proper dosage of the prednisolone given to these children should be 1 mg/kg per day. However the number of the patients in the study were rather small further clinical studies and treatment with 1 mg/kg and 2 mg/kg per day of prednisolone in childhood ITP are warranted.
D000293:Adolescent; D001792:Blood Platelets / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use*; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000188:drug therapy*
D011239:Prednisolone