title: Duplications in Caenorhabditis elegans.
abstract: Thirteen chromosomal duplications, all unlinked to their linkage of origin, have been identified following X-irradiation. Ten are X-chromosome duplications, of which six are half-translocations on three autosomomal linkage groups and four are free fragments. Five of the half-translocations are homozygous fertile and two are recognizable cytologically as chromosome satellites, both of which show some mitotic instability. The free-X duplications show varying tendencies for loss. Three appear not to overlap in extent previously identified free-X duplications. The fourth carries genes from linkage group V, as well as X. Three duplications of a portion of linkage group II were identified and found to be free and quite stable in hyperploids. Some of the free duplications tend to disjoin from the X chromosome in males. New X-chromosome map data are presented.
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D004247:DNA / Q000528:radiation effects*; D004261:DNA Replication; D005260:Female; D008040:Genetic Linkage; D009348:Nematoda / Q000235:genetics*; D014960:X Chromosome; D014965:X-Rays
chemical_list: D004247:DNA