title: The acardiac anomaly.
abstract: Karyotype analysis of a premature human acardiac twin disclosed normal chromosomes. A review of previous cytogenetic, placental and animal studies suggests that chromosomal errors are not the cause of the acardiac anomaly. Rather, they point to the placental vascular anastomoses as the principal pathogenetic event.
mesh_terms: D000015:Abnormalities, Multiple / Q000196:embryology; D009008:Abnormalities, Severe Teratoid / Q000196:embryology* / Q000235:genetics; D000818:Animals; D001188:Artiodactyla; D005260:Female; D006330:Heart Defects, Congenital / Q000196:embryology / Q000235:genetics; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000235:genetics; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D014427:Twins; D014430:Twins, Monozygotic