title: [Morphology of the lymphoid system in the perinatal period under conditions of antigenic stimulation].
abstract: Lymphoid tissue of 29 fetuses and newborns (13 controls and 16 with infections) was studied. In premature babies the thymus responds to antigenic stimulation by accidental involution of the immature type. In addition to the latter, under conditions of the antigenic stimulation the thymus shows either premature maturation with mature reaction, or hypoplasia, or no response (inert thymus). In most cases the antigenic stimulation speeds up maturation of the peripheral lymphoid tissue as confirmed by morphometrical data. Depending on the antigen, however, hypoplasia of the thymus and of the peripheral lymphoid tissue may be observed. Localized infection develops with mature immune system, generalized in immature immune response.
mesh_terms: D001424:Bacterial Infections / Q000276:immunology* / Q000473:pathology; D005260:Female; D005313:Fetal Death / Q000276:immunology / Q000473:pathology; D005315:Fetal Diseases / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000276:immunology* / Q000473:pathology; D007235:Infant, Premature, Diseases / Q000276:immunology / Q000473:pathology; D008208:Lymphatic System / Q000276:immunology / Q000473:pathology*; D011247:Pregnancy
vernacular_title: Morfologiia limfoidnoĭ sistemy v perinatal'nom periode pri antigennom vozdeĭstvii.