[Immunogenic and adjuvant properties of rat erythrocytes subjected to exposure to a high external temperature].
The erythrocytes of Wistar rats, subjected to heating at 40 degrees C (4 times, each heating lasting 40 min.) were found to be more immunogenic in mice than the erythrocytes of intact rats. The immunization of intact Wistar rats, in a single injection, with syngeneic erythrocytes obtained from the heated animals did not induce immunological response reaction, whereas 5 injections of these erythrocytes caused an increase in the number of rosette-forming cells. The injection of syngeneic erythrocytes obtained from the heated rats to intact animals also stimulated the development of immune response to sheep erythrocytes.
D000276:Adjuvants, Immunologic; D000818:Animals; D000917:Antibody Formation; D000921:Antibody-Producing Cells / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology*; D007114:Immunization; D051379:Mice; D051381:Rats; D012397:Rosette Formation; D013696:Temperature; D013997:Time Factors
D000276:Adjuvants, Immunologic
Izuchenie immunogennykh i ad"iuvantnykh svoĭstv éritrotsitov krys, podvergnutykh vozdeĭstviiu vysokoĭ vneshneĭ temperatury.