[Possible use of a single test culture in determining the biological activity of polyene antibiotics].
A possibility using a common test-culture in estimation of biological activity of levorin, amphotericin B, mycoheptin and nistatin was studied. It was found that C. guillier mondii, strain 40, may be used as a common test-culture. It provided satisfactory microbial growth, clear and rather large inhibition growth zones with respect to all the drugs tested.
D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology*; D002174:Candicidin / Q000494:pharmacology; D002175:Candida / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005658:Fungi / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects; D009761:Nystatin / Q000494:pharmacology; D011090:Polyenes; D012440:Saccharomyces / Q000187:drug effects
D000935:Antifungal Agents; D011090:Polyenes; D009761:Nystatin; D002174:Candicidin; D000666:Amphotericin B; C008567:mycoheptin
O vozmozhnosti ispol'zovaniia edinoĭ test-kul'tury pri opredelenii biologicheskoĭ aktivnosti polienovykh antibiotikov.