Edema associated with ibuprofen therapy.
A 15-kg weight gain developed in a patient during the third week of ibuprofen therapy. The edema disappeared with discontinuation of the drug regimen and did not reappear during a subsequent six-month observation period. It should be recognized that ibuprofen may be associated with salt and water retention in the same fashion as previously described with phenylbutazone and indomethacin.
D000368:Aged; D004231:Diuresis / Q000187:drug effects; D004487:Edema / Q000139:chemically induced*; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D010146:Pain / Q000188:drug therapy; D010666:Phenylpropionates / Q000009:adverse effects*
D010666:Phenylpropionates; D007052:Ibuprofen