[Synthesis and antimycotic activity of 3-methylamino derivatives of various 2-mercapto-5-aryl-1,3,4-oxadiazoles].
In continuation of previous work designed to obtain derivatives of 2-mercapto-1,3,4-oxadiazole of possible biological interest, the Mannich bases (III - XXX) were prepared. The compounds prepared bear at position 5, with respect to the oxadiazole nucleus, 3,4,5-trimethoxy and 3,4-dihydroxymethylenephenyl radicals which have proved of interest in other series of derivatives. The antimycotic activity of the compounds is reported.
D000935:Antifungal Agents / Q000138:chemical synthesis*; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000935:Antifungal Agents; D010069:Oxadiazoles
Sintesi e attività antimicotica di 3-metilamminoderivati di alcuni 2-mercapto-5-aril-1,3,4-ossadiazoli.