Increased susceptibility to kindled seizures in rats following a single injection of alcohol.
After 2 or 2.5 g of alcohol, rats previously subjected to low-intensity electrical stimulation of the amygdala showed first a suppression followed by a potentiation of motor seizures and afterdischarges.
D000679:Amygdala / Q000502:physiology; D000818:Animals; D004198:Disease Susceptibility / Q000139:chemically induced*; D004558:Electric Stimulation; D000431:Ethanol / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D007274:Injections, Intraperitoneal; D008297:Male; D051381:Rats; D011930:Reaction Time; D012640:Seizures / Q000209:etiology*; D013375:Substance Withdrawal Syndrome / Q000150:complications
D000431:Ethanol