Thrombotic thrombocytopenic purpura: treatment with a combination of antiplatelet drugs.
Thrombotic thrombocytopenic purpura (TTP) is a rare disease with a vary high mortality. Different modalities of therapy have been tried, but often with no effect. Recently, interest has focused on drugs interfering with platelet function, though few patients have received antiplatelet drugs as the only therapy. We describe a patient with TTP, who recovered completely on a combination therapy with dextran, aspirin and dipyridamole.
D001241:Aspirin / Q000008:administration & dosage / Q000627:therapeutic use*; D001792:Blood Platelets / Q000187:drug effects; D003911:Dextrans / Q000008:administration & dosage / Q000627:therapeutic use*; D004176:Dipyridamole / Q000627:therapeutic use*; D004211:Disseminated Intravascular Coagulation / Q000188:drug therapy; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008875:Middle Aged; D011697:Purpura, Thrombotic Thrombocytopenic / Q000188:drug therapy*
D003911:Dextrans; D004176:Dipyridamole; D001241:Aspirin