title: [New cell line of mouse ependymoblastoma].
abstract: A new cell line derived from transplanted mouse ependimoblastoma consists of typical fibroblast-like cells with well-defined pleomorphism. The line is characterized by a rapid increase and decrease of proliferative activity, by a short stationary phase and early degeneration. The average time of themitotic cycle was determined as being 22-24, tG1-11-12, ts-8-9, tG2-3 and tM-near 0.9 hours. The cytophotometrical evaluation of DNA content revealed two cell subpopulations with different ploidy, both in culture and in tumor in vivo. As compared to the original tumor cells, the cultured cells differ in wider variability of DNA content and a higher average ploidy per nucleus.
mesh_terms: D000818:Animals; D001932:Brain Neoplasms / Q000235:genetics / Q000378:metabolism; D002460:Cell Line; D004273:DNA, Neoplasm / Q000096:biosynthesis; D004806:Ependymoma / Q000235:genetics / Q000378:metabolism; D006651:Histocytochemistry; D051379:Mice; D008940:Mitotic Index; D011003:Ploidies
chemical_list: D004273:DNA, Neoplasm
vernacular_title: Novaia kletochnaia liniia épendoblastomy myshi.