Bladder and urethral responses to isolated sacral motor root stimulation.
After complete intradural lumbosacral rhizotomy and cord transection in 40 cats, parasympathetic discharge was induced by electrical stimulation of the second and third sacral roots. Isolation of the stimulus to the preganglionic motor fiber resulted in bladder contraction and reciprocal urethral pressure loss. The threshold for the urethral response was lower than that of the bladder and the urethral response findings strongly suggest that urethral adrenoreceptor activity can be modified peripherally by a primary parasympathetic stimulus.
D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D005260:Female; D007001:Hypogastric Plexus / Q000187:drug effects / Q000502:physiology; D008297:Male; D009046:Motor Neurons / Q000187:drug effects / Q000502:physiology*; D009119:Muscle Contraction / Q000187:drug effects; D011312:Pressure; D011433:Propranolol / Q000494:pharmacology; D011941:Receptors, Adrenergic / Q000187:drug effects / Q000502:physiology; D013126:Spinal Nerve Roots / Q000187:drug effects / Q000502:physiology*; D014521:Urethra / Q000187:drug effects / Q000294:innervation / Q000502:physiology*; D001743:Urinary Bladder / Q000187:drug effects / Q000294:innervation / Q000502:physiology*
D011941:Receptors, Adrenergic; D011433:Propranolol