title: Effects of the inhibition of aromatic aminoacids decarboxylase on prolactin secretion in humans.
abstract: Carbidopa, at the dose of 250 mg. and benserazide at the dose of 125 mg, given orally in a single dose to healthy women aged between 23 - 26 years enhance significantly serum prolactin. The effect is not shared by two other inhibitors of AADC, namely alpha-methyl DOPA (500 mg) and fentiazac (400 mg). The effect of benserazide is suppressed by bromocriptine (2.5 mg) and blunted by 1-DOPA (400 mg) given orally simultaneusly.
mesh_terms: D000328:Adult; D065105:Aromatic Amino Acid Decarboxylase Inhibitors; D001545:Benserazide / Q000494:pharmacology; D001971:Bromocriptine / Q000494:pharmacology; D002230:Carbidopa / Q000494:pharmacology; D004298:Dopamine / Q000494:pharmacology; D005260:Female; D006801:Humans; D011388:Prolactin / Q000097:blood*
chemical_list: D065105:Aromatic Amino Acid Decarboxylase Inhibitors; D001971:Bromocriptine; D001545:Benserazide; D011388:Prolactin; D002230:Carbidopa; D004298:Dopamine