Hereditary determination of several hemodynamic indices.
Investigation of the genetic determination of hemodynamic indices (the volume of circulating blood, the time of total blood circuit, the rate of lesser blood flow and the minute heart volume) is carried out in 16 mono- and 15 dizygotic twin pairs. The volume of circulating blood only was found to be highly genetically determined (G = 0.90). The role of heredity and environment was almost the same in genesis of the time of total blood circuit and the rate of lesser blood flow (G = 0.34 and 0.48 respectively), while the effect of environment is prevailed for the minute heart volume. The coefficient of genetic determination G is considered to be the most competent estimate among other indices of heredity, because it makes possible to isolate the additive variance and the variance of determing genetic component of phenotypical dispersion of a character. On the basis of the parameters studied, a multifactorial character of hemodynamics indices inheritance is suggested.
D000328:Adult; D001776:Blood Circulation Time; D001783:Blood Flow Velocity; D001810:Blood Volume; D002302:Cardiac Output; D005260:Female; D014644:Genetic Variation; D005838:Genotype; D006439:Hemodynamics; D006801:Humans; D008875:Middle Aged; D010641:Phenotype; D011247:Pregnancy; D011652:Pulmonary Circulation; D014427:Twins; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic
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