[Humoral reactions in BALC/c mice with sarcomatous Moloney-induced tumor].
In a progressive course of the blastomatous process induced by MSV-Moloney the antitumor antibodies level in the whole blood serum was practically unchanged, while the level of antibody-forming cells (AFC) in the spleen of these mice was considerably decreased as compared with that in the spleen of intact mice of the same age. If the tumor development was followed by its subsequent resorption, a biphase character of enhancement of the cytotoxic activity both of the whole serum and its fractions was noted. In the utmost developed tumor a reduced AFC level was observed, while in its resorption -- a gradual restoration of the AFC values up to the level characteristic of intact animals of the same age group.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000921:Antibody-Producing Cells / Q000032:analysis*; D003602:Cytotoxicity, Immunologic; D005260:Female; D051379:Mice; D008807:Mice, Inbred BALB C / Q000276:immunology; D008979:Moloney murine leukemia virus / Q000276:immunology; D012513:Sarcoma, Experimental / Q000276:immunology*; D013154:Spleen / Q000276:immunology; D014412:Tumor Virus Infections / Q000276:immunology
D000914:Antibodies, Viral
Gumoral'nye reaktsii mysheĭ BALB/c pri induktsii opukholi sarkomatoznym virusom Moloni.