Studies on the haemodynamic action of complamin in pregnancy.
In the present work, an attempt has been made to verify whether Complamin improves placental circulation as suggested by several authors. Complamin was administered intravenously to patients in the last trimester of pregnancy and its action on blood pool dynamics was examined over 30 min. The results from 30 investigations showed that a significant reduction in uteroplacental blood pool occurred. The production of placental hypovolaemia, which led to a reduction in blood pool of more than 30% in some cases, is regarded as a potential danger to the fetus.
D000328:Adult; D001810:Blood Volume; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D010920:Placenta / Q000098:blood supply; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D012039:Regional Blood Flow / Q000187:drug effects; D013806:Theophylline / Q000031:analogs & derivatives*; D014971:Xanthinol Niacinate / Q000494:pharmacology*
D014971:Xanthinol Niacinate; D013806:Theophylline