title: Evidence for an action of sodium ions in the activation of contraction of twitch muscle fibre.
abstract: Simultaneous records in current clamp conditions of potential and of contraction of frog skeletal twitch muscle fibre have shown that a part of the contraction directly depends on the intervention of sodium ions (increase in presence of veratrine, decrease in lithium Ringer). The results confirm previous voltage clamp data and suggest a mechanism of sodium induced calcium release.
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001001:Anura; D007473:Ion Channels / Q000502:physiology*; D009119:Muscle Contraction / Q000187:drug effects; D013779:Tetrodotoxin / Q000494:pharmacology; D014702:Veratrine / Q000494:pharmacology
chemical_list: D007473:Ion Channels; D013779:Tetrodotoxin; D014702:Veratrine