[Investigation on the renal clearance of metylglucamine diatrizoate and of sodium and metylglucamine diatrizoate (author's transl)].
In 14 patients the kinetics has been studied of two contrast media labelled with 131I, and namely of MGM diatrizoate and of diatrizoate of sodium and MGM. The clearance was determined both at basal concentrations and in double concentration by means of external counting. The results were statistically studied by means of the linear regression method. The authors conclude that the MGM diatrizoate is exclusively eliminated through the glomeruli both in basal and double concentration. The diatrizoate of sodium and MGM is eliminated in low concentration through the glomeruli, while in double concentration it is partially eliminated through the tubuli.
D000328:Adult; D003973:Diatrizoate / Q000031:analogs & derivatives* / Q000378:metabolism*; D003974:Diatrizoate Meglumine / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007457:Iodine Radioisotopes; D007668:Kidney / Q000378:metabolism*; D007677:Kidney Function Tests; D007678:Kidney Glomerulus / Q000378:metabolism; D007684:Kidney Tubules / Q000378:metabolism; D007700:Kinetics; D008875:Middle Aged; D013997:Time Factors
D007457:Iodine Radioisotopes; D003973:Diatrizoate; D003974:Diatrizoate Meglumine
Studio delle clearance renali del diatrizoato di metilglucamina e del diatrizoato di sodio e metilglucamina.