Granulomatous mastitis. A review of 5 cases.
A review of 67 cases diagnosed as granulomatous, tuberculous or fungal mastitis revealed 5 cases which were similar, clinically and histopathologically, to the new entity of granulomatous mastitis described by Kessler and Wolloch. The 5 patients were young women of childbearing age, 4 with breast lesions clinically simulating carcinoma of the breast. Histopathological examination showed granulomata and abscess formation confined to the breast lobules. No acid-fast bacilli or fungi were demonstrated. Granulomatous mastitis may be caused by a chemical reaction associated with contraceptive pill therapy, or may have an auto-immune or infective aetiology.
D000293:Adolescent; D000328:Adult; D001940:Breast / Q000473:pathology; D003276:Contraceptives, Oral / Q000009:adverse effects; D005260:Female; D006099:Granuloma / Q000139:chemically induced / Q000209:etiology / Q000473:pathology; D006801:Humans; D008413:Mastitis / Q000139:chemically induced / Q000209:etiology / Q000473:pathology*; D011247:Pregnancy
D003276:Contraceptives, Oral