Primary hypothyroidism, amenorrhea, and galactorrhea.
A 30-year-old woman had galactorrhea and secondary amenorrhea, along with symptoms, signs, and laboratory findings of primary hypothyroidism. Serum prolactin and thyrotropin (TSH) levels were elevated. After initiation of thyroid hormone replacement, serum TSH and prolactin levels fell progressively into the normal range. Along with these changes, the patient noted a return of normal menstrual function and the galactorrhea disappeared.
D000328:Adult; D000568:Amenorrhea / Q000097:blood / Q000209:etiology*; D005260:Female; D005687:Galactorrhea / Q000097:blood / Q000209:etiology*; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D007775:Lactation Disorders / Q000209:etiology*; D011247:Pregnancy; D011388:Prolactin / Q000097:blood; D013577:Syndrome; D013974:Thyroxine / Q000627:therapeutic use
D011388:Prolactin; D013974:Thyroxine