title: Disciform detachment of the macula. II. Fluorescein and indocyanine green fluorescence angiographic findings in juvenile haemorrhagic macular choroidopathy.
abstract: Six patients with juvenile haemorrhagic mascular choroidopathy were studied with fluorescein and indocyanine green fluorescence (ICG) angiography, and red-light and red-free light photography in different stages of the disease. The primary lesion consisted of multifocal, whitish, dot-like areas of choroidal infiltration showing hyperfluorescence in the late phase of the fluorescein angiograms. Red-light photographs revealed depigmentation of the pigment epithelium overlying the choroidal lesion, and clearly demonstrated the subsequent pigment-ring lesion. Fluorescein angiograms revealed subretinal neovascularization at the site of the disciform-stage choroidal lesion. ICG angiograms revealed the choridal lesion to be located in the region of greatest supply of short posterior ciliary arteries, wheras the lesion itself remained underfilled throughout the angiogram suggesting vascular decompensation at the site of the lesion. The results suggest a vascular basis, namely intravascular coagulation in the central choriocapillaris, for this uveitis entity.
mesh_terms: D002829:Choroid; D004211:Disseminated Intravascular Coagulation; D005451:Fluorescein Angiography; D005452:Fluoresceins; D006660:Histoplasmosis; D006801:Humans; D007208:Indocyanine Green; D008266:Macula Lutea; D009898:Optic Disk; D010857:Pigment Epithelium of Eye; D012163:Retinal Detachment / Q000175:diagnosis*; D012166:Retinal Hemorrhage
chemical_list: D005452:Fluoresceins; D007208:Indocyanine Green