[Studies on the metabolism of parenterally infused amino acids in healthy adults].
We studied the metabolic kinetics after short-time infusion of a 10% standardised L-amino-acid-mixture in 19 healthy adults. The following results were of special interest: 1. Nearly all amino-acids had half life times between 7 and 10 minutes. 2. The male adults showed averagely higher clearance and transfer rates in contrast to female. There was a statistical difference for serine and alanine in the transfer rates, for serine, methionine and glycine in the clearance. 3. The maximum of daily turnover could be calculated for about 5,6 g/kg body weight. Based on the measured transfer rates we discuss the composition of some standardised L-amino-acid-mixtures.
D000328:Adult; D000409:Alanine / Q000378:metabolism; D000596:Amino Acids / Q000008:administration & dosage / Q000378:metabolism*; D005260:Female; D005998:Glycine / Q000378:metabolism; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008715:Methionine / Q000378:metabolism; D012694:Serine / Q000378:metabolism; D012737:Sex Factors
D000596:Amino Acids; D012694:Serine; D008715:Methionine; D000409:Alanine; D005998:Glycine
Untersuchungen über die Verwertung parenteral zugeführter Aminosäuren bei gesunden Erwachsenen.