[Possible experimental model of Korsakoff's syndrome].
Study of the effects of chronic alcohol intoxication on conditioned behaviour in rats revealed spatial desorientation, the lack of a stable level of alertness, "negative attitude" to novelty, automatism of motor habit and periodical impairment of temporary connection reproduction. The authors conclude that the observed changes are comparable to a certain degree with the clinical pattern of Korsakov syndrome.
D000425:Alcohol Amnestic Disorder / Q000503:physiopathology; D000818:Animals; D003214:Conditioning, Classical / Q000502:physiology; D004195:Disease Models, Animal; D006801:Humans; D051381:Rats; D011930:Reaction Time / Q000502:physiology
Vozmozhnaia éksperimental'naia model' sindroma Korsakova.