[Influence of estrogen on the delayed action of prostaglandin F2alpha on the rat uterine contraction (author's transl)].
Responsiveness of the rat uterus on the day of estrus to PGE2, PGF2alpha and oxytocin was increased by administration of PGF2alpha i.p. 24 hours prior to the experiments, but that of the uterus on the day of diestrus was not altered by the same treatment. The delayed action of PGF2alpha was not observed in the uterus of ovariectomized rats, but was observed in the uterus of estrogen treated rats. The delayed action of PGF2alpha was not evident in either the vas deferens or the intestine of the rat.
D000818:Animals; D002369:Castration; D004031:Diestrus; D004970:Estrone / Q000494:pharmacology*; D004971:Estrus; D005260:Female; D008297:Male; D010121:Oxytocin / Q000494:pharmacology; D011247:Pregnancy; D011458:Prostaglandins E / Q000494:pharmacology; D011460:Prostaglandins F / Q000494:pharmacology*; D051381:Rats; D014590:Uterine Contraction / Q000187:drug effects*
D011458:Prostaglandins E; D011460:Prostaglandins F; D004970:Estrone; D010121:Oxytocin