title: [Characteristics of fucidin biosynthesis by a Fusidium coccineum 257 A strain].
abstract: The physiological features of Fusidium coccineum, strain 257 A,  an organism producing fusidin were studied. It was found that increased concentrations of the carbon sources in the medium stimulated production of fusidin, while an increase in the content of various forms of nitrogen differently affected the level of the antibiotic viosynthesis: high concentrations of the amino acid-peptide form of nitrogen of corn-steep liquor decreased, while the protein form of nitrogen was associated with consumption of the significant part of carbon in the medium for formation of the fungus mycelium. Therefore, the concentration of the easily mobilizing forms of nitrogen may be considered as a regulator of the growth process of F. coccineum 257 A and production of fusidin by it.
mesh_terms: D050260:Carbohydrate Metabolism; D003470:Culture Media / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005672:Fusidic Acid / Q000096:biosynthesis*; D003904:Mitosporic Fungi / Q000254:growth & development / Q000378:metabolism*; D009584:Nitrogen / Q000378:metabolism
chemical_list: D003470:Culture Media; D005672:Fusidic Acid; D009584:Nitrogen
vernacular_title: Izuchenie osobennosteĭ biosinteza fuzidina shtammom Fusidium coccineum 257 A