title: [Cowden's disease].
abstract: We report a typical case of Cowden disease or Multiple Hamartoma Syndrome in a 32 year old female without a family history of this illness. The patient suffered bilateral fibrocystic disease of the breast, having been subjected to mastectomy because of carcinomatous degeneration. She complained of gastric symptoms, and the x-ray examination showed multiple polyposis. On physical examination an asymptomatic thyroid nodule was noted. The skin showed multiple wart-like lesions, lichenoid papules, localized hyperkeratosis and pigmented spots. She had many papillomas in her mouth a rasberry tongue and bilateral perleches.
mesh_terms: D000328:Adult; D005260:Female; D006222:Hamartoma / Q000150:complications*; D006801:Humans; D007569:Jaw Abnormalities / Q000150:complications*; D009056:Mouth Abnormalities / Q000150:complications*; D009061:Mouth Mucosa / Q000473:pathology; D010212:Papilloma / Q000473:pathology; D011127:Polyps / Q000150:complications / Q000000981:diagnostic imaging; D011859:Radiography; D012867:Skin / Q000473:pathology; D013272:Stomach Diseases / Q000150:complications / Q000000981:diagnostic imaging; D013577:Syndrome
vernacular_title: Enfermedad de Cowden.