title: Tympanoplasty using formaldehyde formed fascia grafts.
abstract: The closure of total perforations of the tympanic membrane has always been more difficult than lesser eardrum defects. Postoperative anterior sulcus blunting and graft lateralization occur with greater frequency in this situation and thus compromise results. In 1975, Rodney Perkins developed and described a technique for the closure of such total perforations which involved the use of formaldehyde treated temporalis muscle fascia, shaped by means of a metal mold into the configuration of a normal tympanic membrane and medial end of the bony external ear canal. This formaldehyde formed fascia (FFF) graft impressed us with its adaptability and logic. This article is a review of 139 cases involving the use of formaldehyde treated grafts not only for closure of total performations, but also for closure of total performations with concomitant middle ear ossicular reconstruction. The postoperative nonperforation rate in this series is 96.4%; blunting and/or graft lateralization was absent in 94.2% of cases. Closures of the air-bone gap to within 20 db occurred in 74% of cases with an overall gain in hearing for all cases of 84%. We believe that formaldehyde formed fascia grafts are an effective tool for the closure of total tympanic membrane perforations with or without concomitant ossicular chain reconstruction.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005205:Fascia / Q000637:transplantation*; D005557:Formaldehyde; D006801:Humans; D008875:Middle Aged; D012421:Rupture; D014182:Transplantation, Autologous; D014432:Tympanic Membrane / Q000293:injuries; D014433:Tympanoplasty / Q000379:methods*
chemical_list: D005557:Formaldehyde