Simultaneous clinical manifestation of subependymoma of the fourth ventricle in identical twins. Case report.
At the age of 22 years, identical twin brothers simultaneously developed symptoms of intracranial pressure. Radiological investigation revealed cerebellar midline tumors with occlusive hydrocephalus of the third and lateral ventricles. At operation, subependymomas with identical histological features were found in the fourth ventricle in both twins. This is the first report of subependymomas in identical twins. The clinical data suggest that this tumor type is of maldevelopmental origin.
D000328:Adult; D002551:Cerebral Ventricle Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D004200:Diseases in Twins / Q000473:pathology / Q000601:surgery; D004806:Ependymoma / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D014430:Twins, Monozygotic