Pedigree analysis of the hypothermal recovery of the effects of gamma-rays on hepatoma cells.
Cultured hepatoma cells of the rat were irradiated with 400 to 900 R of gamma-rays. They were kept at room temperature for several hours before transferred to normal culture condition at 37 degrees C. The pedigree analysis of growing cells recorded by cinematography indicated a variety of lethal and non-lethal recovery events such as a decrease in lethal branch formation and an increase in locomotion. The so-called repair immediately after irradiation has many facets depending upon dose and duration of the low temperature treatment.
D000818:Animals; D002453:Cell Cycle / Q000528:radiation effects; D002455:Cell Division / Q000528:radiation effects*; D002465:Cell Movement / Q000528:radiation effects; D002470:Cell Survival / Q000528:radiation effects; D002478:Cells, Cultured; D003080:Cold Temperature; D005720:Gamma Rays; D008114:Liver Neoplasms, Experimental / Q000473:pathology