The effect of exogenous nucleosides on postimplantation development of mouse embryos.
Exogenous nucleosides, either singly or in combination, do not enhance postimplantation development of mouse embryos in vitro, and adenosine, guanosine and thymidine are toxic to the embryos at high concentrations.
D000241:Adenosine / Q000494:pharmacology; D000818:Animals; D003562:Cytidine / Q000494:pharmacology; D004622:Embryo, Mammalian / Q000187:drug effects*; D047108:Embryonic Development; D005260:Female; D006151:Guanosine / Q000494:pharmacology; D066298:In Vitro Techniques; D051379:Mice; D009705:Nucleosides / Q000494:pharmacology*; D011247:Pregnancy; D013936:Thymidine / Q000494:pharmacology; D014529:Uridine / Q000494:pharmacology
D009705:Nucleosides; D006151:Guanosine; D003562:Cytidine; D000241:Adenosine; D013936:Thymidine; D014529:Uridine