Correlation between antiestrogenic and antiovulatory activity of some newer substituted coumarins.
Seven 7-(4-substituted thiosemicarbazido methoxy)-4-methyl coumarins were found to antagonize the uterotropic effects of estradiol and blocked the copper acetate induced ovulation in rabbits.
D000818:Animals; D003374:Coumarins / Q000494:pharmacology* / Q000633:toxicity; D003864:Depression, Chemical; D004965:Estrogen Antagonists; D005260:Female; D051379:Mice; D010060:Ovulation / Q000187:drug effects*
D003374:Coumarins; D004965:Estrogen Antagonists