Immunological evaluation in patients with urological cancers.
The immunological competence of 100 patients bearing urological cancers was evaluated by means of skin tests and serum immunoelectrophoresis. Cell-mediated immunodepressions were observed in 93.3% of prostatic cancers, 68.6% of bladder cancers and 38.4% of renal cancers. The immunoglobulin values increased in 80% of prostatic cancers, 31.3% of bladder cancers and in 23% of renal cancers. IgA was elevated in almost all the prostatic growths. In bladder and renal cancers a clear correlation between immunodepression and tumour stage was found. Treatment significantly improved the skin test reactivity in the evaluated patients. Metastases and recurrences occurred more frequently in immunodepressed subjects.
D000230:Adenocarcinoma / Q000276:immunology*; D000368:Aged; D002648:Child; D004407:Dysgerminoma / Q000276:immunology*; D005260:Female; D006801:Humans; D007109:Immunity; D007136:Immunoglobulins / Q000032:analysis; D007680:Kidney Neoplasms / Q000276:immunology; D008297:Male; D011471:Prostatic Neoplasms / Q000276:immunology; D012882:Skin Tests; D013736:Testicular Neoplasms / Q000276:immunology; D001749:Urinary Bladder Neoplasms / Q000276:immunology; D014565:Urogenital Neoplasms / Q000276:immunology*
D007136:Immunoglobulins