title: Caustic ingestions: a rational look at diluents.
abstract: Treatment of lye ingestions by antidotes recommended on product labels includes the use of acid neutralizers. The possibility that heat produced by this exothermic reaction increased tissue damage was examined in vitro. Although Drano produced heat with all diluents including water and milk, acid antidotes prolonged the duration of high temperature. Clinitest tablets neutralized with milk produced no temperatures above 40 degrees C. The ready availability of milk or water, their acceptance by the child, and lack of toxic side effects make them diluents of choice for alkaline corrosive agents.
mesh_terms: D000085:Acetates; D000818:Animals; D000931:Antidotes; D002424:Caustics / Q000506:poisoning*; D055598:Chemical Phenomena; D002621:Chemistry; D002957:Citrus; D006801:Humans; D008892:Milk; D013696:Temperature; D013997:Time Factors; D014867:Water
chemical_list: D000085:Acetates; D000931:Antidotes; D002424:Caustics; D014867:Water