title: [Synthesis of bronchospasmolytically effective beta phenylethyl-aminoalkyl-xanthines].
abstract: New theophylline and theobromine derivatives are synthetized from the beta-phenylethylaminoalkyl-xanthines, whose phenyl substituent is substitutent by one or two hydroxyl groups and partially also by other substituents. Different methods of synthesis are described, among them the production of the bronchospasmolytic 7-(3-[2-(3,5-dihydroxyphenyl)-2-hydroxy-ethylamino]-propyl)-theophylline (reproterol-HCl).
mesh_terms: D001993:Bronchodilator Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D010627:Phenethylamines / Q000138:chemical synthesis*; D013806:Theophylline / Q000031:analogs & derivatives; D014970:Xanthines / Q000138:chemical synthesis*
chemical_list: D001993:Bronchodilator Agents; D010627:Phenethylamines; D014970:Xanthines; D013806:Theophylline
vernacular_title: Synthesen von bronchospasmolytisch wirksamen beta-Phenläthyl-aminoalkyl-xanthinen