title: Development of Dipetalonema viteae third-stage larvae (Nematoda: Filarioidea) in micropore chambers implanted into jirds, hamsters, normal and immunized mice.
abstract: Development of third-stage larvae of Dipetalonema viteae within subcutaneously implanted micropore chambers proceeded in all hosts tested up to the fourth-stage larvae and occasionally to adolescent worms. In the jird the timing of development was comparable to a natural infection. Although the mouse is an insusceptible host, larval development could take place, but was very slow. Two intraperitoneal inoculations of living third-stage larvae into mice induced the production of antibodies against the larval cuticle and against common antigens. In such immune mice the development of third- and fourth-stage larvae within micropore chambers was significantly inhibited, larval mortality was increased, and the larval motility was impaired.
mesh_terms: D000818:Animals; D000906:Antibodies / Q000032:analysis; D006224:Cricetinae / Q000469:parasitology*; D004153:Dipetalonema / Q000254:growth & development* / Q000276:immunology; D006790:Host-Parasite Interactions; D007114:Immunization; D007814:Larva / Q000254:growth & development; D008297:Male; D008647:Mesocricetus / Q000469:parasitology*; D051379:Mice / Q000469:parasitology*; D012377:Rodentia / Q000469:parasitology*; D013045:Species Specificity
chemical_list: D000906:Antibodies