Interaction of erythrocytes with human serum proteins. II. Dependence of the process on the concentration of protein, exposure and temperature of medium.
The effect of concentration of human serum proteins, duration of contact and temperature of the medium on the process of their interaction with formalized, tannin-treated sheep erythrocytes was studied. Dependence of the process of specific haemosensitization on the enumerated factors was established. The character of the process of haemosensitization by serum proteins and its dependence on the concentration of sensitins and the duration of the contact with them can be expressed by Langmuir's equation. On the basis of limited preliminary experiments it is thus possible to define the optimum conditions for the loading of erythrocytes.
D001798:Blood Proteins / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology*; D006386:Hemagglutination Tests; D006801:Humans; D008259:Macroglobulins / Q000276:immunology; D012709:Serum Albumin / Q000276:immunology; D012712:Serum Globulins / Q000276:immunology; D013696:Temperature; D013997:Time Factors
D001798:Blood Proteins; D008259:Macroglobulins; D012709:Serum Albumin; D012712:Serum Globulins