A radio-immunological assay for triamcinolone in plasma.
A specific radioimmunoassay for the determination of picogram quantities of triamcinolone in plasma is reported. A rapid chemical separation method was incorporated in the procedure to remove the interfering endogenous hydrocortisone which cross reacts (5%) with the antiserum. Application of this radioimmunoassay to the analysis of triamcinolone plasma concentrations following oral administration of a 5 mg dose of the drug to a human volunteer is described.
D000818:Animals; D000918:Antibody Specificity; D003429:Cross Reactions; D006801:Humans; D008722:Methods; D011817:Rabbits / Q000276:immunology; D011863:Radioimmunoassay; D013256:Steroids / Q000276:immunology; D013997:Time Factors; D014221:Triamcinolone / Q000097:blood* / Q000276:immunology
D013256:Steroids; D014221:Triamcinolone