title: Sequential bilateral germ cell tumors of the testis despite interval chemotherapy.
abstract: We report on 3 patients who had a second primary germ cell tumor of the testis despite prior or ongoing systemic chemotherapy for the original tumor. Evidence favoring the designation of the tumors as separate primary lesions is presented. The clinical and theoretical implications of this phenomenon are discussed.
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002822:Choriocarcinoma / Q000188:drug therapy; D004359:Drug Therapy, Combination; D004407:Dysgerminoma / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009362:Neoplasm Metastasis; D009378:Neoplasms, Multiple Primary; D013724:Teratoma / Q000188:drug therapy; D013736:Testicular Neoplasms / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents