title: [Formation of chondroid tissue in the left ventricle and bundle of His in complex congenital cardiac abnormality (author's transl)].
abstract: The formation of chondroid tissue in the heart ventricles and in the region of the ventriculoatrial transition is regarded as a rare lesion of the human heart. We present the observation of a not well-known disorder of cardiac development connected with a cartilagineous transformation of endo- and myocardial tissue. Chondroid change was found in the innermost parts of the left ventricle in a heart with severe hypoplasia of left parts and aortic atresia. Cartilage-like tissue reached to the region of the bundle of His and to supraanular parts of the interatrial septum. The possible genesis of this change, that may be of clinical relevance, is discussed with regard to normal endo- and myocardial development.
mesh_terms: D001344:Autopsy; D002036:Bundle of His / Q000473:pathology; D002356:Cartilage / Q000473:pathology*; D006330:Heart Defects, Congenital / Q000473:pathology*; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male
vernacular_title: Knorpelbildung im Bereich des linken Ventrikels und des Hisschen Bündels bei einem komplexen angeborenen Herzvitium.