[Mechanisms of the reversibility of the stathmokinetic response induced by suboptimal temperature].
Autoradiographic research with leucine-3H showed that the reversibility of the statmokinetic reaction induced by the suboptimal temperature (21 degrees C) did not require any additional protein synthesis and therefore was not connected with the neoformation of the microtubules. Normalization of the mitotic rate was delayed in the presence of copper ions preventing polymerization of microtubules. These data suggest that repolymerization of microtubules subunits was the principal way of mitosis recovery after the action of suboptimal temperature.
D000818:Animals; D002999:Clone Cells; D003300:Copper / Q000494:pharmacology; D006224:Cricetinae; D008870:Microtubules / Q000378:metabolism; D008938:Mitosis; D014176:Protein Biosynthesis; D013696:Temperature
D003300:Copper
Mekhanizmy obratimosti statmokineticheskoĭ reaktsii, vyzvannoĭ suboptimal'noĭ temperaturoĭ.