title: Male pseudohermaphrodite reared as a female.
abstract: A 31-year-old male pseudohermaphrodite has been brought up as a female. The parents had told their child not to discuss the problem of ambiguous genitalia with anyone. As a teenager masculinization had occurred. Chromosome analysis of both peripheral blood and gonadal tissue was 46XY. The internal gonads were testes surrounded by a rim of ovarian stroma. A rudimentary cervix opened into a small vagina, as did the urethra in a valve-like fashion. The phallus was amputated during surgical reconstruction of the external genitalia to create a phenotypic female and the vagina was enlarged. Oestrogen therapy resulted in breast development.
mesh_terms: D002668:Child Rearing; D012734:Disorders of Sex Development / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D004997:Ethinyl Estradiol / Q000627:therapeutic use; D005260:Female; D005783:Gender Identity; D006066:Gonads / Q000601:surgery; D006801:Humans; D008297:Male; D009640:Norethindrone / Q000627:therapeutic use; D013518:Surgery, Plastic; D014621:Vagina / Q000601:surgery
chemical_list: D004997:Ethinyl Estradiol; D009640:Norethindrone