Barrier contraceptive practice and male infertility as related factors to breast cancer in married women. Preliminary results.
A case-control study was conducted in order to test the hypothesis that a reduced exposure to human seminal factors in the early reproductive life of women is a risk factor in breast cancer. The relative risk of exposure to the hypothetical semen-factor deficiency is 4.7 times greater for breast-cancer patients than for the controls. The risk of developing breast cancer within the same population in the U.S.A. is estimated as 5 times greater for women who use barrier methods (condom and other) than for women who use non-barrier contraceptive methods (diaphragm and other). The reduction of the incidence of breast cancer by eliminating the barrier contraceptive techniques would be not less than 50% in married women in the population.
D000328:Adult; D001943:Breast Neoplasms / Q000209:etiology*; D003271:Contraceptive Agents, Female; D003273:Contraceptive Devices / Q000009:adverse effects*; D003274:Contraceptive Devices, Female; D003275:Contraceptive Devices, Male / Q000009:adverse effects; D005260:Female; D006801:Humans; D007248:Infertility, Male; D008297:Male; D008393:Marriage; D008875:Middle Aged; D012306:Risk; D012661:Semen / Q000502:physiology*
D003271:Contraceptive Agents, Female