Anti-androgen-therapy in pachydermia of the female larynx--a new therapeutic possibility.
Case-report about a 56 year old white female patient with pachydermia laryngis and hirsutism, successfully treated with cyproterone-acetate, a testosterone antagonist. The significance of androgenic hormones for the development of epithelial changes in the female larynx is emphasized. The administration of antiandrogenic substances as a new therapeutic measure is discussed.
D015065:17-Hydroxycorticosteroids / Q000652:urine; D015068:17-Ketosteroids / Q000652:urine; D003534:Cyproterone / Q000627:therapeutic use*; D004967:Estrogens / Q000652:urine; D005260:Female; D006628:Hirsutism / Q000150:complications / Q000188:drug therapy / Q000652:urine; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000652:urine; D008875:Middle Aged; D011230:Precancerous Conditions / Q000150:complications / Q000188:drug therapy* / Q000652:urine; D013739:Testosterone / Q000652:urine; D014827:Vocal Cords
D015065:17-Hydroxycorticosteroids; D015068:17-Ketosteroids; D004967:Estrogens; D013739:Testosterone; D003534:Cyproterone