title: Biological standardization of potency testing of diphtheria-tetanus-pertussis vaccines.
abstract: Active protection tests were introduced for the potency testing of the toxoid components of the DTP vaccine. The standardization of these tests is described, with special attention on WHO requirements. A freeze-dried, adsorbed DTP vaccine was prepared for use under tropical or subtropical conditions. The potency testing of the components of this vaccine is presented in this paper.
mesh_terms: D000818:Animals; D004168:Diphtheria Toxoid / Q000276:immunology / Q000592:standards*; D005260:Female; D006168:Guinea Pigs; D006814:Hungary; D007109:Immunity; D008297:Male; D051379:Mice; D010567:Pertussis Vaccine / Q000276:immunology / Q000592:standards*; D013745:Tetanus Toxoid / Q000276:immunology / Q000592:standards*
chemical_list: D004168:Diphtheria Toxoid; D010567:Pertussis Vaccine; D013745:Tetanus Toxoid