title: Studies on the effects of O-isopropoxyphenylmethyl carbamate on the meiotic chromosomes of Saccobranchus fossilis.
abstract: O-isopropoxyphenylmethyl carbamate in S. fossilis chromosomes has been found to induce fragmentation at pachytene and diakinesis. Fragmentation frequency increased with the increase in dose. The yield of total clumping at different doses and different intervals was inconsistent. Precocious despiralization and stickiness were also observed. Time interval was observed to be a factor in the appearance of anomalies with different doses. The dicentric bridges which were frequent at low dose, diminished in quantum with the increase in dose.
mesh_terms: D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002875:Chromosomes / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005399:Fishes / Q000235:genetics*; D005854:Germ Cells / Q000648:ultrastructure; D007306:Insecticides / Q000633:toxicity; D007700:Kinetics; D008540:Meiosis / Q000187:drug effects*; D009152:Mutagenicity Tests; D001074:Propoxur / Q000633:toxicity*
chemical_list: D007306:Insecticides; D001074:Propoxur