The fetal hydantoin syndrome. A case report.
A patient with the fetal hydantoin syndrome is described. The features include mild to moderate mental deficiency, craniofacial anomalies, prenatal onset of growth deficiency and varying limb abnormalities. Recognition of this spectrum of abnormalities in an infant should raise the possibility of maternal ingestion of hydantoin during pregnancy. The dangers of therapy with this drug during pregnancy are emphasized.
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000328:Adult; D004827:Epilepsy / Q000188:drug therapy; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D006827:Hydantoins / Q000009:adverse effects*; D007223:Infant; D008297:Male; D010672:Phenytoin / Q000009:adverse effects; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy
D006827:Hydantoins; D010672:Phenytoin