Vaccination of calves against Taenia saginata infection using antigens collected during in vitro cultivation of larvae: passive protection via colostrum from vaccinated cows and vaccination of calves protected by maternal antibody.
Six-to-11-day-old calves which received colostrum from cows vaccinated with in vitro culture antigens of Taenia saginata during their last month of pregnancy showed a high level of resistance to a challenge infection with T saginata eggs. Although colostral antibody reduced the numbers of larvae which became established it did not promote destruction of those which had undergone development. Calves which had received colostrum from vaccinated dams were themselves vaccinated with culture antigen when they were eight to 10 weeks old. These calves showed strong immunity to a challenge infection of T saginata eggs administered four weeks after vaccination.
D000818:Animals; D000941:Antigens / Q000302:isolation & purification*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D003126:Colostrum / Q000276:immunology*; D005260:Female; D007112:Immunity, Maternally-Acquired; D011247:Pregnancy; D013621:Taenia / Q000254:growth & development / Q000276:immunology*; D013622:Taeniasis / Q000276:immunology / Q000662:veterinary*; D014611:Vaccination / Q000662:veterinary*
D000941:Antigens