Evidence for an action of sodium ions in the activation of contraction of twitch muscle fibre.
Simultaneous records in current clamp conditions of potential and of contraction of frog skeletal twitch muscle fibre have shown that a part of the contraction directly depends on the intervention of sodium ions (increase in presence of veratrine, decrease in lithium Ringer). The results confirm previous voltage clamp data and suggest a mechanism of sodium induced calcium release.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001001:Anura; D007473:Ion Channels / Q000502:physiology*; D009119:Muscle Contraction / Q000187:drug effects; D013779:Tetrodotoxin / Q000494:pharmacology; D014702:Veratrine / Q000494:pharmacology
D007473:Ion Channels; D013779:Tetrodotoxin; D014702:Veratrine