title: [Obstetrical problems in patients with Glanzmann's thrombasthenia. A casuistic presentation (author's transl)].
abstract: Glanzmann's thrombasthenia is a rare, autosomal recessive disorder of bleeding arrest. The differential diagnosis of this platelet defect with respect to recently gained knowledge is presented in the case of a pregnant woman. Because of pelvic presentation a cesarean section was performed after adequate platelet substitution, which did not involve excessive blood loss. A severe puerperal infection necessitated an abdominal hysterectomy after appropriate platelet transfusion. The difficulties in testing platelet function in the newborn are discussed. The effectiveness of a commercially available homologous phospholipide complex (Fibraccel) was tested on the patient in a noncritical phase. The results appear important for general procedure when pregnancy and platelet dysfunction concur.
mesh_terms: D000328:Adult; D001946:Breech Presentation; D002585:Cesarean Section; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007231:Infant, Newborn; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000628:therapy*; D011645:Puerperal Infection / Q000601:surgery; D011696:Purpura, Thrombocytopenic / Q000235:genetics* / Q000628:therapy; D013577:Syndrome
vernacular_title: Geburtshilfliche Probleme bei Thrombasthenie Glanzmann-Naegeli.