[Transmembrane ionic currents in neuroblastoma cells].
Isolated neuroblastoma cells (clone A-1 from clone N-18) were investigated by means of the intracellular dialysis technique. Changes in the ionic composition of intra- and extracellular media show that the fast inward current is carried by Na ions and delayed outward current is carried by K ions. Na inward current was blocked by TTX. Calcium inward current was not observed. Substitution of Na ions for K ions showed that PNa: PK = 7:1. A relatively low potassium conductance was found in the neuroblastoma cells.
D000200:Action Potentials; D000818:Animals; D002118:Calcium / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism*; D002999:Clone Cells; D051379:Mice; D009447:Neuroblastoma / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D013779:Tetrodotoxin / Q000494:pharmacology
D013779:Tetrodotoxin; D012964:Sodium; D011188:Potassium; D002118:Calcium
Transmembrannye ionnye toki v kletkakh neĭroblastomy.