title: Effect of calcitonin on the phosphorylation of non-histones from cultured bone cells.
abstract: 32P-uptake into non-histones from bone cell cultures was selectively stimulated in the presence of calcitonin. Comparison of the control and experimental radioactivity profiles of non-histones fractionated by SDS gel electrophoresis showed that, in response to calcitonin stimulation, there was a 2- to 3-fold increase in the specific activity associated with non-histone proteins in the molecular weight range of 10,000 to 45,000 daltons while that of bands between 50,000 to 200,000 decreased.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002116:Calcitonin / Q000494:pharmacology*; D002478:Cells, Cultured / Q000032:analysis / Q000187:drug effects / Q000378:metabolism*; D002868:Chromosomal Proteins, Non-Histone / Q000032:analysis / Q000096:biosynthesis*; D006657:Histones / Q000032:analysis; D008970:Molecular Weight; D010758:Phosphorus / Q000378:metabolism*; D051381:Rats; D012886:Skull
chemical_list: D000596:Amino Acids; D002868:Chromosomal Proteins, Non-Histone; D006657:Histones; D010758:Phosphorus; D002116:Calcitonin