Regulation of initiation of DNA synthesis in relation to mitosis in cultured hepatoma cells.
The commitment of Reuber H 35 hepatoma cells to DNA synthesis was studied by exposing cells which were synchronized by serum depletion, to serum. It is shown that the period of commitment is 6--8 during the G2 period of the previous cell cycle.
D000818:Animals; D002453:Cell Cycle; D002478:Cells, Cultured; D004261:DNA Replication; D008114:Liver Neoplasms, Experimental / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D008938:Mitosis; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D014316:Tritium; D013936:Thymidine