Clinical, biochemical, and radiologic reversibility of hyperprolactinemic galactorrhea-amenorrhea and abnormal sella by thyroxine in a patient with primary hypothyroidism.
A case of primary hypothyroidism associated with postpartum galactorrhea-amenorrhea is reported. The configuration of the sella was compatible with pituitary adenoma, but prolactin dynamics did not support an autonomous secretory state. Replacement therapy with thyroxine led to complete reversal of clinical, radiologic, and biochemical abnormalities.
D000328:Adult; D000568:Amenorrhea / Q000209:etiology* / Q000378:metabolism; D005260:Female; D005687:Galactorrhea / Q000209:etiology* / Q000378:metabolism; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism; D007775:Lactation Disorders / Q000209:etiology*; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*; D011859:Radiography; D012658:Sella Turcica / Q000000981:diagnostic imaging*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000627:therapeutic use*
D011388:Prolactin; D013972:Thyrotropin; D013006:Growth Hormone; D013974:Thyroxine