[Treatment of hypercholesterolemia in the male rat by introduction of soya oil supplemented or not with sardine oil in the diet].
Substituting soya oil for lard considerably reduced hypercholesterolemia in the male rat with induced hypercholesterolemia due to a dietary overlead of cholesterol and sodium deoxycholate. The decrement was more marked when a mixture of 80 p. 100 soya oil + 20 p. 100 sardine oil replaced the lard. This improvement of the hypocholesterolemic effect by adding sardine oil to soya oil was due to the long-chain fatty acids (mainly C20:5 and/or C22:5 n-3 in the fish oil).
D000818:Animals; D004041:Dietary Fats / Q000627:therapeutic use*; D005227:Fatty Acids / Q000032:analysis; D005399:Fishes; D006937:Hypercholesterolemia / Q000188:drug therapy*; D008297:Male; D009821:Oils / Q000627:therapeutic use*; D051381:Rats; D013025:Glycine max
D004041:Dietary Fats; D005227:Fatty Acids; D009821:Oils
Traitement de l'hypercholestérolémie chez le rat male par introduction dans la ration d'huile de soja supplémentée ou non par de l'huile de sardine.