[Reaction performance, motor coordination performance and findings in hypertensive patients under diisopropylamine and reserpine therapy].
In 64 male hypertonics the reaction and coordination functions and the condition were standardized and compared before and after a four weeks ambulatory treatment with diisopropylamine (3 times 200 mg a day) and reserpine (3 times 0.25 mg a day). The two medicaments achieved good blood pressure reducing effects. Since in reserpine the therapeutic effect later appeared, fatigue and need for sleep were more frequent and continuous, in older patients still after a treatment of four weeks right and temporary reactions decreased, wrong reaction increased and the aim accelerated, is concluded that here in particular in the behaviour of older people more frequently a longer lasting disturbance is probable.
D000328:Adult; D000367:Age Factors; D001794:Blood Pressure / Q000187:drug effects; D005221:Fatigue / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009048:Motor Skills / Q000187:drug effects; D011437:Propylamines / Q000009:adverse effects / Q000494:pharmacology*; D011930:Reaction Time / Q000187:drug effects; D012110:Reserpine / Q000009:adverse effects / Q000494:pharmacology*; D012890:Sleep / Q000187:drug effects
D011437:Propylamines; D012110:Reserpine; C007442:diisopropylamine
Reaktionsleistungen, motorische Koordinationsleistungen und Befinden von Hypertonikern unter Diisopropylamin und Reserpin.