title: Responses to intensive training and methandrostenelone administration. I. Contractile and performance variables.
abstract: The purpose of this study was to investigate the effects of methandrostenelone (Dianabol) on contractile and performance variables in the rat. Thirty-six male Sprague Dawley rats 90 days old were divided into sedentary and exercise groups; they were further subdivided into Dianabol (0.35 mg/kg/day) treated and untreated groups. The exercise groups underwent a program of high intensity training 7 days/week for 6 weeks. Training produced changes in isometric force-time characteristics indicating increased production of tension. Performance test scores increased significantly from 3 weeks to 6 weeks. Performance by exercise and exercise with Dianabol groups was indistinguishable. It is concluded that Dianabol did not significantly alter the adaptations of the rat to high intensity training.
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D008297:Male; D008696:Methandrostenolone / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects*; D010805:Physical Conditioning, Animal; D005082:Physical Exertion; D051381:Rats
chemical_list: D008696:Methandrostenolone