Changes in membrane fluidity of mast cells, induced by antigen-anaphylactic antibody reaction.
Binding of IgE to rat mast cell receptors caused a distinct decrease of membrane fluidity. The antigen-IgE antibody reaction was followed by rapid changes in membrane fluidity of sensitized mast cells. In the earliest phase of the antigen-antibody reaction membrane fluidity decreased, however, this decrease was followed by a quick increase 10 min. later.
D000707:Anaphylaxis / Q000276:immunology*; D000818:Animals; D000936:Antigen-Antibody Complex; D007073:Immunoglobulin E / Q000032:analysis; D008407:Mast Cells / Q000276:immunology* / Q000378:metabolism; D008560:Membrane Fluidity; D051381:Rats; D013050:Spectrometry, Fluorescence
D000936:Antigen-Antibody Complex; D007073:Immunoglobulin E