title: Isocitrate dehydrogenase in Aedes aegypti: formal genetics, preliminary linkage data and study of natural populations.
abstract: Two loci for isocitrate dehydrogenase (Idh-1 ad Idh-2) are described in Ae. aegypti, both polymorphic with two codominant alleles. Crosses made to test linkage relationships of Idh-1 indicate that this locus is independent from sex (chromosome 1) and from Sod-1 and Hk-1 loci (chromosome 3), while it is linked to Pgm on the second chromosome. Average percent of recombination is 11.37, but significant differences have been found among strains. Data on genetic variability of Idh-1 and Idh-2 in three domestic african field populations are presented.
mesh_terms: D000330:Aedes / Q000201:enzymology* / Q000235:genetics; D000818:Animals; D005260:Female; D005799:Genes, Dominant; D008040:Genetic Linkage; D006579:Heterozygote; D006593:Hexokinase / Q000235:genetics; D007521:Isocitrate Dehydrogenase / Q000235:genetics*; D007527:Isoenzymes / Q000235:genetics*; D008297:Male; D011110:Polymorphism, Genetic; D013482:Superoxide Dismutase / Q000235:genetics
chemical_list: D007527:Isoenzymes; D007521:Isocitrate Dehydrogenase; D013482:Superoxide Dismutase; D006593:Hexokinase