title: Changing form and function in one ventricle hearts.
abstract: Postnatal changes in morphology of hearts with one functioning ventricle influence physiology, natural history and physical signs. The most important and early changes relate to the acquiring of subpulmonary or subaortic stenosis. For this to occur, the basic anatomy has to be of particular arrangement; investigators should be aware of the problems and search for gradients both at rest and on Isuprel stimulation when the anatomy is appropriately disturbed. Atrio-ventricular valve regurgitation and calcification may also develop. Many changes are predictable from study of the basic pathology and knowledge of them helps to plan management at the correct time in the living patient.
mesh_terms: D000328:Adult; D002114:Calcinosis / Q000209:etiology; D002312:Cardiomyopathy, Hypertrophic / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D006345:Heart Septal Defects, Ventricular / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D007223:Infant; D008297:Male; D008944:Mitral Valve Insufficiency / Q000209:etiology; D011859:Radiography; D014262:Tricuspid Valve Insufficiency / Q000209:etiology