title: Diurnal and seasonal variations in human platelet serotonin in man.
abstract: Platelet serotonin (5-HT) was found to be an individually constant parameter correlating with the uptake of exogenous 5-HT. A pronounced diurnal pattern of 5-HT, with a minimum in the afternoon and higher values in the morning and evening, was similar to the diurnal variations in plasma free tryptophan. Platelet 5-HT was  significantly higher at 8 a.m. than 4 p.m. in spring but no longer in autumn, and was similar in both men and women. It appeared that peripheral diurnal variations in 5-HT were opposite in phase to the central 5-HT rhythm.
mesh_terms: D000328:Adult; D001792:Blood Platelets / Q000032:analysis*; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012621:Seasons; D012701:Serotonin / Q000097:blood*; D012737:Sex Factors; D014364:Tryptophan / Q000097:blood
chemical_list: D012701:Serotonin; D014364:Tryptophan