[The Lesch-Nyhan syndrome as a rare cause of hemolytic anemia].
The Lesch Nyhan Syndrome is a rare cause of hemolytic anemia. By electron microscopy, platelets of a patient with this disorder lacked a marginal bundle nearly completely--and had morphologically an abnormal structure. This may be a hint with respect to the pathogenesis of this unresolved syndrome.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000745:Anemia, Hemolytic, Congenital / Q000201:enzymology*; D001792:Blood Platelets / Q000648:ultrastructure; D004912:Erythrocytes / Q000378:metabolism; D006160:Guanosine Triphosphate / Q000378:metabolism; D006801:Humans; D007926:Lesch-Nyhan Syndrome / Q000175:diagnosis* / Q000201:enzymology; D010198:Pancytopenia / Q000201:enzymology
D006160:Guanosine Triphosphate; D000255:Adenosine Triphosphate
Das Lesch-Nyhan-Syndrom als seltene Ursache einer hämolytischen Anämie.