Thrombotic thrombocytopenic purpura with C'3 vascular deposits: report of a case.
A case of thrombotic thrombocytopenic purpura in a young woman in which platelet microthrombi were distributed in small vessels throughout the body is reported. IgM and complement (C'3) were demonstrated in capillary and small arteriole walls by immunofluorescent microscopy. These findings support the findings of a previous case report, and are further evidence for a possible primary immune etiology for thrombotic thrombocytopenic purpura.
D000328:Adult; D001158:Arteries / Q000378:metabolism; D001808:Blood Vessels / Q000032:analysis*; D002196:Capillaries / Q000378:metabolism; D003176:Complement C3 / Q000378:metabolism*; D003165:Complement System Proteins / Q000378:metabolism*; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000378:metabolism*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000276:immunology*
D003176:Complement C3; D007075:Immunoglobulin M; D003165:Complement System Proteins