[Action of embryonic thymus and liver cells on the development of the ascitic form of Ehrlich's carcinoma].
The influence of the cells of embryonic thymus and liver on the development of Ehrlich carcinoma was studied. The intraperitoneal injection of the embryonic cells in the adult mice infested by the Ehrlich carcinoma resulted in a marked lengthening of the life time of animals and an increase of the survival percentage. The embryonic cells of thymus and liver inhibited sharply the growth of carcinoma cells in the diffusion chambers as well. In contrast to this, the thymus and bone marrow cells of adult animals, taken in the same concentrations as the embryonic cells, exhibited only a slight inhibiting effect on the growth of tumour cells. On the basis of these data a suggestion is put forward to the effect that the embryonic immunocompetent cells determine the stronger inhibition of tumour growth in the embryos as compared with the adult animals.
D000818:Animals; D000921:Antibody-Producing Cells / Q000637:transplantation; D002286:Carcinoma, Ehrlich Tumor / Q000209:etiology* / Q000276:immunology; D008099:Liver / Q000196:embryology* / Q000276:immunology; D051379:Mice; D008805:Mice, Inbred A; D008810:Mice, Inbred C57BL; D013950:Thymus Gland / Q000196:embryology* / Q000276:immunology; D014181:Transplantation Immunology
Deĭstvie kletok embrional'nogo timusa i pecheni na razvitie astsitnoĭ formy kartsinomy Erlikha.