[Further investigations on the protective effect of cadmium acetate in bromotrichloromethane poisoning].
The rats were pretreated with cadmium acetate (20 mg/Kg.ip) and subsequently challenged with a dose of bromotrichloromethane (2,6 mmoles/Kg.po), the haloalkane produced no change on liver polyribosomes, as evidenced by disaggregation of sedimentation profile. Cadmium acetate failed to protect against CBrCl3-induced lipid peroxidation, as measured by malonaldehyde production of liver homogenate.
D000085:Acetates; D000818:Animals; D001975:Bromotrichloromethane / Q000633:toxicity*; D002104:Cadmium / Q000494:pharmacology*; D011232:Chemical Precipitation; D002725:Chloroform / Q000031:analogs & derivatives*; D050356:Lipid Metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008315:Malondialdehyde / Q000378:metabolism; D010544:Peroxidases / Q000378:metabolism; D011132:Polyribosomes / Q000187:drug effects; D051381:Rats
D000085:Acetates; D002104:Cadmium; D008315:Malondialdehyde; D002725:Chloroform; C028031:cadmium acetate; D010544:Peroxidases; D001975:Bromotrichloromethane
Ulteriori indagini sul'effetto protettivo dell'acetato di cadmio nella intossicazione da triclorobromometano.