Diurnal intraocular pressure in juvenile open-angle glaucoma.
Outpatient diurnal intraocular pressures were obtained on 10 patients with juvenile open-angle glaucoma at approximately 6 hour intervals. There were 8 males and 2 females with an age range of 19 to 38 years. All glaucomatous medications were stopped 24 hours before recording the tensions. The peak intraocular pressure was recorded at the 6 PM interval in 6 of the 10 patients. Three patients recorded their highest pressures at the 12 AM (midnight) interval. Extraordinarily wide angles were observed in all cases and myopia was a common refractive error. Although the family history was not known in 3 patients, there was a positive family history of glaucoma in 7 of the 10 patients, which suggests an autosomal dominant mode of inheritance.
D000328:Adult; D000367:Age Factors; D002940:Circadian Rhythm; D005260:Female; D005901:Glaucoma / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male