[Effect of neuroleptics, midantan and DOPA on apomorphine sterotypy in rats].
The influence of differently structured neuroleptics on the stereotypyd attitude of rats, induced by apomorphine, was inquired into. Most of the known neuroleptics manifested an inhibitory effect on the apomorphine-induced stereotypy. Clozapine and azabutyrone were effective only in a dose of 25 mg/kg, while carbidine and promazine failed to exert any marked influence on the stereotypy. It seems that the antiapomorphine effect does not correlate with the antipsychotic activity of the neuroleptics.
D000547:Amantadine / Q000494:pharmacology*; D000818:Animals; D001058:Apomorphine / Q000037:antagonists & inhibitors*; D001519:Behavior / Q000187:drug effects*; D004295:Dihydroxyphenylalanine / Q000494:pharmacology*; D006801:Humans; D008297:Male; D051381:Rats; D013239:Stereotyped Behavior / Q000187:drug effects*; D014149:Tranquilizing Agents / Q000494:pharmacology*
D014149:Tranquilizing Agents; D004295:Dihydroxyphenylalanine; D000547:Amantadine; D001058:Apomorphine
Vliianie neĭroleptikov, midantana i DOFA na apomorfinovuiu sterotipiiu u krys