Valine, leucine, and isoleucine metabolism by lactating bovine mammary tissue.
Valine, leucine, and isoleucine were extracted by the lactating bovine mammary gland in excess of outputs in milk protein. Carbon-14 uniformly labeled L-valine, L-leucine or L-isoleucine were catabolized when incubated in vitro with lactating bovine mammary tissue slices. The pathways of degradation of these amino acids by mammary tissue appear to be those common to other tissues. These amino acids represent a potential source of energy to the mammary gland as well as a source of carbon and alpha-amino nitrogen for synthesis of nonessential amino acids.
D000085:Acetates / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D002417:Cattle; D005260:Female; D005947:Glucose / Q000378:metabolism; D007532:Isoleucine / Q000378:metabolism*; D007651:Keto Acids / Q000378:metabolism; D007774:Lactation; D007930:Leucine / Q000378:metabolism*; D008321:Mammary Glands, Animal / Q000378:metabolism*; D008892:Milk / Q000378:metabolism; D008894:Milk Proteins / Q000378:metabolism; D011247:Pregnancy; D014633:Valine / Q000378:metabolism*
D000085:Acetates; D000596:Amino Acids; D007651:Keto Acids; D008894:Milk Proteins; D007532:Isoleucine; D007930:Leucine; D014633:Valine; D005947:Glucose