[The post-transfusional toxoplasmosis (author's transl)].
The sera of 85 patients suffering from Cooley anemia, 100 normal children of the same group of age, and 550 blood donors have been tested for the presence of anti-toxoplasma antibodies by indirect immunofluorescence test. The sera of 10 thalassemic patients gave positive reactions at a dilution reaging from 1/64 to 1/2048; in 2 sera a positive reaction was obtained with specific anti-IgM antibodies, indicating an active infection. In the control group, only 2 positive sera have been found. In donors group, instead, 5 sera were positive, and in 2 cases IgM antibodies were detectable. The analysis of data confirms, although indirectly, that heavily transfused patients are at a particular risk to acquire the infection from Toxoplasma Gondii.
D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000628:therapy; D000906:Antibodies / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D006801:Humans; D013789:Thalassemia / Q000628:therapy; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis / Q000175:diagnosis / Q000209:etiology*; D065227:Transfusion Reaction
D000906:Antibodies
Note sulla toxoplasmosi post-trasfusionale.