title: Role of activation and sensory stimuli in recovery from lateral hypothalamic damage in the cat.
abstract: The early stages of recovery from lateral hypothalamic lesions were analyzed in 30 adult cats. In addition to aphagia and adipsia, neurological examination revealed deficits suggestive of deficient endogenous arousal, including somnolence, catalepsy, akinesia, and sensory neglect. Manipulations (tail pinch and injection of amphetamine) that counteracted these deficits also restored feeding. During recovery from aphagia, feeding gradually became activated by sensory stimuli (sight, feel, and smell) associated with food. These data suggest that activation is an important component in the control of normal feeding.
mesh_terms: D000374:Aggression / Q000502:physiology; D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D001143:Arousal / Q000502:physiology*; D001522:Behavior, Animal / Q000502:physiology; D002415:Cats; D004327:Drinking Behavior / Q000502:physiology; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology; D005260:Female; D006706:Homeostasis; D006801:Humans; D007031:Hypothalamus / Q000502:physiology*; D008297:Male; D009069:Movement Disorders / Q000209:etiology; D011930:Reaction Time; D012677:Sensation / Q000502:physiology*
chemical_list: D000661:Amphetamine