title: [Cardiovascular effect of infukoll 6% on normotensive late pregnancy].
abstract: By means of quantitative sphygmometry and the unbloody recording of arterial blood pressure the hemodynamic effect of an infusion of 500 ml dextrane 75 (Infukoll 6%) on the cardiovascular systeme in 10 normovolemic normotensive healthy late pregnant women is examined. Hematocrit decreases as an expression of increasing plasma volume. Arterial blood pressure and heart rate remain unchanged. Stroke volume and cardiac output increase significantly. Simultaneously total peripheral resistance decreases. Therefore dextrane 75 is indicated in pregnancy for therapy and prophylaxis of circulatory conditions with lowered plasma volume.
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D002306:Cardiac Volume / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects*; D003911:Dextrans / Q000494:pharmacology*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006400:Hematocrit; D006801:Humans; D010953:Plasma Volume / Q000187:drug effects; D011247:Pregnancy; D011263:Pregnancy Trimester, Third
chemical_list: D003911:Dextrans
vernacular_title: Herz-Kreislaufwirkung von Infukoll 6% bei normotensiven Spätschwangeren.