The fine structure of macrophage granules in experimental granulomas in rodents.
Macrophages in granulomas in four rodent species contain cytoplasmic granules with an ordered substructure similar to those previously described in human granuloma macrophages. These appearances, as well as other ultrastructural features of the cells, are compatible with the view that those macrophages have a secretory function.
D000818:Animals; D003594:Cytoplasmic Granules / Q000648:ultrastructure*; D006099:Granuloma / Q000473:pathology*; D006168:Guinea Pigs; D006614:Hindlimb / Q000473:pathology; D008264:Macrophages / Q000648:ultrastructure*; D008297:Male; D051379:Mice; D008854:Microscopy, Electron; D011817:Rabbits; D051381:Rats