Stimulatory effect of Panax ginseng principles on DNA and protein synthesis in rat testes.
The effect of fraction 4 of the extract from the roots of Panax ginseng, Oura, on DNA and protein syntheses was investigated. Addition of fraction 4 in vitro stimulated DNA and protein syntheses in testes. The stimulating effect was reduced by pretreatment with cycloheximide. This might give some evidence about the stimulatory effect of ginseng on spermatogenesis.
D000818:Animals; D003513:Cycloheximide / Q000494:pharmacology; D004247:DNA / Q000096:biosynthesis*; D066298:In Vitro Techniques; D008297:Male; D005894:Panax; D010936:Plant Extracts / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D010946:Plants, Medicinal; D014176:Protein Biosynthesis; D051381:Rats; D013268:Stimulation, Chemical; D013737:Testis / Q000187:drug effects / Q000378:metabolism*
D010936:Plant Extracts; D004247:DNA; D003513:Cycloheximide