title: Pineal melatonin concentrations in the Syrian hamster.
abstract: Pineal melatonin concentrations exhibited a marked diurnal rhythmicity in gold hamsters maintained in a light-dark cycle of 15 h of light and 10 h of darkness. When tissue was collected at 3-h intervals throughout a 24-h period, daytime levels of 95--232 pg/pineal gland rose to concentrations of 760--1335 pg/pineal gland (P greater than 0.001 vs. all other values) at 0400 h, 8 h after the onset of darkness. When tissue was collected sequentially during the dark phase, pineal melatonin concentrations remained significantly elevated from 0200--0500 h (P less than 0.01 and P less than 0.001 vs. daytime values, respectively). Superior cervical ganglionectomy abolished the rhythm of pineal melatonin concentrations, and the concentrations were maintained at 60--105 pg/pineal gland throughout a 24-hr period.
mesh_terms: D000818:Animals; D002940:Circadian Rhythm; D006224:Cricetinae; D003624:Darkness; D005727:Ganglia, Spinal / Q000502:physiology; D008027:Light; D008297:Male; D008550:Melatonin / Q000378:metabolism*; D008647:Mesocricetus; D010870:Pineal Gland / Q000378:metabolism*
chemical_list: D008550:Melatonin