The effect of nystatin on active transport in Rhodotorula glutinis (gracilis) is restricted to the plasma membrane.
The effect of the polyene antibiotic nystatin on the energy-requiring transport of substrates in the obligatory aerobic yeast Rhodotorula glutinis (gracilis) is restricted to its interaction with the plasma membrane, whereas the energy metabolism in mitochondria remains unaffected by the antibiotic. A method for preparation of the mitochondrial fraction from this yeast is described.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000968:Antimycin A / Q000494:pharmacology; D001693:Biological Transport, Active / Q000187:drug effects*; D002462:Cell Membrane / Q000378:metabolism*; D007700:Kinetics; D003904:Mitosporic Fungi / Q000378:metabolism*; D009761:Nystatin / Q000494:pharmacology*; D010101:Oxygen Consumption / Q000187:drug effects; D012248:Rhodotorula / Q000187:drug effects / Q000378:metabolism*; D014994:Xylose / Q000378:metabolism
D009761:Nystatin; D000968:Antimycin A; D000255:Adenosine Triphosphate; D014994:Xylose