Influence of infralow-frequency magnetic fields of high and ultrahigh intensity on the division of mammalian cells in vivo.
The influence of an infralow-frequency magnetic field (IMF) with intensity 3-127 k0e for 1 h on the mitotic activity, frequency of chromosome aberrations, and number of corneal epithelial cells of mice was studied. It was shown that the changes in mitotic activity that arise can be explained by a reversible inhibition of cell division at late stages of the mitotic cycle and synchronous entry into mitosis after the removal of this inhibition. The nature of the dependence of the effect on the intensity of the IMF is evidence of a difference in its molecular mechanisms in the region of high and ultrahigh intensities. As a result of the influence of an IMF of the intensity and duration used, no increase in the frequency of aberrant mitoses in corneal epithelial cells was detected. The number of cells in a standard visual field of the microscope also was practically unchanged.
D000818:Animals; D002452:Cell Count; D002869:Chromosome Aberrations; D003315:Cornea / Q000166:cytology*; D004847:Epithelial Cells; D008280:Magnetics; D051379:Mice; D008938:Mitosis; D008940:Mitotic Index