An inhibitor of cell cohesion from axenically grown cells of the slime mould, Dictyostelium discoideum.
Medium from a stationary phase culture of axenically grown D. discoideum cells contains an inhibitor of cohesion of log phase cells. The inhibitor is a heat-stable, low molecular weight substance. Its biological effects include inhibition of cohesion of aggregation-competent cells, of cells of other slime mould species, the blocking of development on Millipore filters and a reduction in adhesiveness of slime mould cells to glass. Present evidence suggests that the inhibitor may bind to the cell surface.
D000268:Adhesiveness; D002457:Cell Extracts / Q000494:pharmacology; D003470:Culture Media; D004023:Dictyostelium / Q000032:analysis* / Q000254:growth & development; D008970:Molecular Weight; D009235:Myxomycetes / Q000032:analysis*; D013045:Species Specificity
D002457:Cell Extracts; D003470:Culture Media