Histone and non-histone proteins from rabbit mammary gland at late pregnancy and early lactation.
The content of non-histone protein in epithelial cell chromatin from rabbit mammary gland increased during late pregnancy and early lactation up to 30%, while the histone content remained unchanged. No qualitative changes, as judged by polyacrylamide-gel electrophoresis, were found during accumulation of non-histone proteins at the onset of lactation. The chromatin isolated at lactation, assayed either by polylysine or Toluidine Blue binding, contained slightly more available DNA-phosphate than the chromatin isolated at pregnancy.
D000818:Animals; D002843:Chromatin / Q000032:analysis; D005260:Female; D006657:Histones / Q000032:analysis*; D007774:Lactation; D008321:Mammary Glands, Animal / Q000032:analysis*; D011107:Polylysine / Q000378:metabolism; D011247:Pregnancy; D011506:Proteins / Q000032:analysis*; D011817:Rabbits; D014048:Tolonium Chloride / Q000378:metabolism
D002843:Chromatin; D006657:Histones; D011506:Proteins; D014048:Tolonium Chloride; D011107:Polylysine