title: The anthelmintic efficacy of albendazole against gastrointestinal roundworms, tapeworms, lungworms and liverflukes in sheep.
abstract: Anthelmintic trials were carried out to evaluate the efficacy of albendazole against helmi of 2,5 to 3,8 mg/kg administered orally, resulted in a 98,8 to 100% reduction of adult parasites of the genera Haemonchus, Ostertagia, Trichostrongylus, Nematodirus, Gaigeria, Oesophagostomum, Chabertia, Marshallagia and Cooperia. Against the immature stages of these genera, except for Marshallagia and Cooperia, which were not tested, a dose level of 2,5 to 3,8 mg/kg was 83,9-100% effective. Albendazole at 2,5 mg/kg was 99,0% effective against adult stages of Dictyocaulus; its activity at a dose of 3,8 mg/kg against the immature stages of D. filaria was 89,3%. In sheep naturally infested with Moniezia, 100% elimination was obtained at a dose level of 2,5 mg/kg. Dose levels of 3,8 mg/kg and higher were more than 76% effective against adult Fasciola hepatica, while a dose of 4,8 mg/kg was 63% effective against adult Fasciola gigantica.
mesh_terms: D015766:Albendazole; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D002590:Cestode Infections / Q000188:drug therapy / Q000662:veterinary; D005767:Gastrointestinal Diseases / Q000188:drug therapy / Q000662:veterinary*; D006373:Helminthiasis / Q000188:drug therapy; D006374:Helminthiasis, Animal; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary; D012756:Sheep / Q000469:parasitology*; D012757:Sheep Diseases / Q000188:drug therapy* / Q000469:parasitology; D014201:Trematode Infections / Q000188:drug therapy / Q000662:veterinary
chemical_list: D000871:Anthelmintics; D001562:Benzimidazoles; D015766:Albendazole