title: Nucleotide sequence of a region of human mitochondrial DNA containing the precisely identified origin of replication.
abstract: A fragment of HeLa cell mitochondrial DNA containing the origin of replicaton has been sequenced. The precise position of the origin in this sequence has been identified by determining the nucleotide order in the 5'-end proximal portion of the heavy strand initiation fragment (7S DNA), and by aligning the two sequences.
mesh_terms: D001483:Base Sequence; D004261:DNA Replication; D004272:DNA, Mitochondrial / Q000235:genetics*; D006367:HeLa Cells; D006801:Humans; D006860:Hydrogen Bonding; D008928:Mitochondria / Q000502:physiology*; D008970:Molecular Weight; D009690:Nucleic Acid Conformation
chemical_list: D004272:DNA, Mitochondrial