Genetic characterization of the new morphological and UV-sensitive mutants in Coprinus cinereus. I. A UV-sensitive mutation rad 1 associated with elevated frequencies of mitotic and meiotic recombination.
Studies on the effect of an UV-sensitive mutation, rad 1, in meiotic and mitotic recombination in Coprinus indicated that, in homozygous condition, rad 1 increased the spontaneous meiotic recombination by 50% and UV-induced mitotic intergenic recombination by about 5-fold. The homozygous rad 1 diploid was shown to be much more sensitive to the recombinogenic effects of polyfunctional than than of mono- or non-functional alkylating agents.
D000363:Agaricales / Q000528:radiation effects*; D003302:Coprinus / Q000235:genetics / Q000528:radiation effects*; D003433:Crosses, Genetic; D008540:Meiosis / Q000528:radiation effects*; D008938:Mitosis / Q000528:radiation effects*; D009154:Mutation; D014466:Ultraviolet Rays