Failure of sodium loading or deficiency to affect plasma prolactin in the male rat.
The relation between plasma prolactin (PRL) and sodium metabolism was studied in adult male rats. During the experiments attention was given to the avoidance of stress. Cannulated rats were infused with 2.5 ml 5% NaCl over a 40 min period. Plasma PRL did not change during or up to 2 h after this infusion. Other rats were subjected to a sodium deficient diet for 3 weeks. This treatment which induced a marked rise in plasma aldosterone, did not cause a change in plasma PRL. It is concluded that PRL does not have an important role in the regulation of sodium balance.
D000818:Animals; D004039:Diet, Sodium-Restricted; D008297:Male; D011388:Prolactin / Q000097:blood*; D051381:Rats; D012964:Sodium / Q000172:deficiency*; D012965:Sodium Chloride / Q000494:pharmacology*
D012965:Sodium Chloride; D011388:Prolactin; D012964:Sodium