Selective breeding of rats for differences in reactivity to alcohol. An approach to an animal model of alcoholism. II. Behavioral measures.
Two lines of rats have been bred which differ in sensitivity to alcohol over a range of doses, but the difference is not reflected in blood alcohol concentration, alcohol intake or selection. The two lines respond similarly on tests of emotionality; however, differences in running-wheel activity suggest differences in neural apparatus.
D000428:Alcohol Drinking; D000437:Alcoholism / Q000503:physiopathology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001947:Breeding; D004195:Disease Models, Animal; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D009043:Motor Activity / Q000187:drug effects*; D051381:Rats
D000431:Ethanol