title: Ultrastructural changes in the adenohypophysis, adrenal gland activity, and desynchronization of the oestrous cycle following unpredictable stress in the rat.
abstract: An ultrastructural study of the adenohypophysis, after exposure of female Wistar rats to a signalled unpredictable 5- and 15-day stress regimen, is described. Cellular activity of the adenohypophysis correlated well with the circulating levels of corticosterone. Intense secretory activity was observed in all tropic cell types at 5 and 15 days although the observed differences generally were greater in the 5-day stressed group. It was observed that the oestrous cycles of 40 and 100% of the rats became desynchronized over the 5- and 15-day stress period respectively.
mesh_terms: D000818:Animals; D003345:Corticosterone / Q000097:blood*; D004971:Estrus; D005260:Female; D010903:Pituitary Gland, Anterior / Q000648:ultrastructure*; D011247:Pregnancy; D051381:Rats; D013312:Stress, Physiological / Q000097:blood / Q000473:pathology* / Q000503:physiopathology
chemical_list: D003345:Corticosterone