Effects of methomyl and ethanol on behavior in the Sprague-Dawley rat.
Emotional behavior and activity levels were studied following administration of ethanol and/or a carbamate pesticide, methomyl, to rats via a ground chow diet. Acetylcholinesterase levels were lowered following the experimental diets. The group having the greatest reduction in AChE, the methomyl group, showed less evidence for habituation in an open-field test. No differences relative to control subjects were noted on handling and muricide tests.
D000374:Aggression / Q000187:drug effects; D000375:Aging; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001835:Body Weight / Q000187:drug effects; D002802:Cholinesterases / Q000097:blood; D004644:Emotions / Q000187:drug effects; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D007306:Insecticides / Q000494:pharmacology*; D008297:Male; D008724:Methomyl / Q000494:pharmacology*; D009043:Motor Activity / Q000187:drug effects; D051381:Rats
D007306:Insecticides; D008724:Methomyl; D000431:Ethanol; D002802:Cholinesterases