title: [Comparative study on the volume effect of a 2/3 electrolyte solution and of a 4 per cent dextran solution during the 1st stage of anesthesia].
abstract: In 224 orthopedic patients the volume effect of a 2/3 strength electrolyte solution was compared to a 4% dextran solution of low molecular weight during the early period of anesthesia. Basic circulatory parameters like medium arterial pressure, pressure amplitude and heart beats per minute were measured. It was supposed that a different volume effect could be expected according to the difference in composition of the two solutions. However no statistically significant difference of the determined circulatory parameters could be demonstrated after comparison of both populations. It was concluded that both intravenous solutions have the same effect on the circulatory volume within the time period under investigation i.e. 20 minutes before until 15 minutes after intubation.
mesh_terms: D000136:Acid-Base Equilibrium / Q000187:drug effects; D000758:Anesthesia; D001158:Arteries / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D001834:Body Water / Q000187:drug effects; D003911:Dextrans / Q000494:pharmacology*; D004573:Electrolytes / Q000494:pharmacology*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008970:Molecular Weight; D012996:Solutions; D013997:Time Factors; D014882:Water-Electrolyte Balance / Q000187:drug effects
chemical_list: D003911:Dextrans; D004573:Electrolytes; D012996:Solutions
vernacular_title: Vergleichende Untersuchung über die Volumenwirkung einer Zweidrittel-Elektrolytlösung sowie einer 4%igen Dextranlösung in der Phase der Narkoseeinleitung.