Synthesis of a mannosyl phosphoryl polyprenol by the cellular slime mold Dictyostelium discoideum.
A membrane fraction isolated from the cellular slime mold Dictyostelium discoideum was incubated with GDP-[14C]mannose and found to catalyze the incorporation of [14C]mannose into an endogenous acceptor to yield a product with the chemical and chromatographic properties of a polyprenol phosphate sugar derivative. These results suggest that D. discoideum can synthesize a mannosyl phosphoryl polyprenol.
D004023:Dictyostelium / Q000378:metabolism*; D006155:Guanosine Diphosphate Mannose / Q000378:metabolism; D006600:Hexosephosphates / Q000096:biosynthesis*; D008358:Mannose / Q000096:biosynthesis; D009235:Myxomycetes / Q000378:metabolism*; D013729:Terpenes / Q000096:biosynthesis*
D006600:Hexosephosphates; D013729:Terpenes; D006155:Guanosine Diphosphate Mannose; D008358:Mannose