title: [Clinical and hormonal development of a case of malignant exophthalmus after hypophyseal myskiotomy].
abstract: A pituitary myskiotomy was performed in a 26-years old man with Graves' disease and progressive exophtalmus. At the onset of Graves' disease a high level of serum TSH, LATS and thyroid hormones was found. Following pituitary miskiotomy a stationary exophtalmus and other signs of Graves' disease have been recorded. The serum levels of LATS and thyroid hormones were high. The serum concentration of TSH decreased to a level undetectable even after the TRH stimulation test. It is discussed the pathogenesis of Graves' disease: its onset due to neuroendocrine disturbances (S. M. Milcu) and its evolution due to autoimmune mechanisms.
mesh_terms: D000328:Adult; D006111:Graves Disease / Q000097:blood*; D006801:Humans; D008135:Long-Acting Thyroid Stimulator / Q000097:blood; D008297:Male; D010902:Pituitary Gland / Q000601:surgery*; D013963:Thyroid Hormones / Q000097:blood; D013972:Thyrotropin / Q000097:blood
chemical_list: D013963:Thyroid Hormones; D013972:Thyrotropin; D008135:Long-Acting Thyroid Stimulator
vernacular_title: Evolution clinique et hormonale d'un cas d'exophtalmie maligne après myskiotomie hypophysaire.