[Autoimmune panhemopathy in lymphoid hyperplasia in a child].
The case reported concerns a 12 year old boy, admitted in 1970 with a clinical picture evoking a malignant hemopathy: thrombocytopenic purpura, leukopenia, multiple lymphadenopathies, enlarged spleen and, at histological examination, lympho-reticular hyperplasia of the spleen and lymphe nodes, simulating at the beginning, a nodular lymphoma. Immuno-hematological investigations revealed a complex auto-immune picture, which concerned essentially hematopoiesis. In fact, the pseudo-tumoral aspect of lymphenodes, was related to a dysfunction of the immune system, the pathogeny of which is presently better known.
D001327:Autoimmune Diseases / Q000175:diagnosis; D002648:Child; D003937:Diagnosis, Differential; D006402:Hematologic Diseases / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007970:Leukopenia / Q000150:complications; D008206:Lymphatic Diseases / Q000150:complications / Q000175:diagnosis*; D008223:Lymphoma / Q000175:diagnosis; D008297:Male; D011696:Purpura, Thrombocytopenic / Q000150:complications; D013163:Splenomegaly / Q000150:complications
D007136:Immunoglobulins
Panhemopathie auto-immune avec hyperplasie lymphoide chez un enfant.