Effects of combining pilocarpine, d-amphetamine, and either a free feeding schedule or cyclic food deprivation on mouse killing by rats.
The combination of a drug which suppresses mouse killing by rats (d-amphetamine) , a drug which activates mouse killing (pilocarpine), and either ad-lib food or a 24-hour cyclic food deprivation schedule were examined for their effects on the mouse-killing response by rats (N = 53). Results showed that the presence of d-amphetamine prevented the activating effects of pilocarpine in rats with a fairly high killing propensity regardless of whether they were on the ad-lib food or the deprivation schedule. The study suggests that a drug which affects both eating behavior and mouse killing is more effective in determining behavioral outcomes than a drug which affects only mouse killing.
D000374:Aggression / Q000187:drug effects / Q000502:physiology; D000818:Animals; D003913:Dextroamphetamine / Q000494:pharmacology*; D004336:Drug Antagonism; D005247:Feeding Behavior / Q000187:drug effects; D005508:Food Deprivation; D006801:Humans; D010862:Pilocarpine / Q000494:pharmacology*; D051381:Rats; D011930:Reaction Time
D010862:Pilocarpine; D003913:Dextroamphetamine