2-(Aminomethyl)-2-decarboxyprostaglandin F2 alpha type analogs.
The 2-(aminomethyl)-2-decarboxy analogs of prostaglandin F2 alpha (PGF2 alpha), (15S)-15-methyl-PGF2 alpha, 16-phenoxy-omega-tetranor-PGF2 alpha and 16,16-dimethyl-PGF2 alpha were synthesized. The amino analogs closely resemble the parent PGF2 alpha compounds as antifertility agents in the hamster.
D000019:Abortifacient Agents / Q000138:chemical synthesis*; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D006224:Cricetinae; D004353:Drug Evaluation, Preclinical; D005260:Female; D011247:Pregnancy; D011461:Prostaglandins F, Synthetic / Q000138:chemical synthesis*
D000019:Abortifacient Agents; D011461:Prostaglandins F, Synthetic