title: Type and amount of dietary fat affect relative concentration of cholesterol in blood and other tissues of rats.
abstract: The effects of diet on tissue cholesterol disposition in the rat were studied. Growing rats were fed a nonfat dry milk supplemented with two levels of soy-bean oil (SBO) and tallow (T) such that either 30% or 50% of total dietary calories came from fat. Two of four groups of rats fed the diets with 50% of calories from fat were supplemented with 20% ground whole oats. Considering all diets, rats fed SBO had higher blood and kidney cholesterol than did rats fed T; supplementation of the diet with oats increased the plasma cholesterol of the "50%" SBO rats and , conversely, decreased plasma cholesterol of the "50%" T rats. Muscle cholesterol content was not affected by variations in dietary fat and oats. In all treatments, cholesterol concentration of epididymal fat and liver were greater in the SBO-fed than in the T-fed rats.
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000097:blood*; D004041:Dietary Fats / Q000008:administration & dosage*; D004043:Dietary Fiber / Q000008:administration & dosage; D002523:Edible Grain; D005224:Fats, Unsaturated / Q000008:administration & dosage; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009929:Organ Size; D051381:Rats; D013025:Glycine max
chemical_list: D004041:Dietary Fats; D004043:Dietary Fiber; D005224:Fats, Unsaturated; D002784:Cholesterol