title: The efficacy of fenbendazole in the control of immature strongyle infections in ponies.
abstract: The efficacy of fenbendazole against immature stages of Trichonema spp., Strongylus vulgaris and Strongylus edentatus was evaluated. Naturally infected 6 to 12 month old ponies were given single, oral doses of 0, 15, 30 and 60 mg/kg of body weight. A dose response relationship was noted between increasing dose levels and efficiency against larval trichonemes and migrating stages of S. vulgaris and S. edentatus. Dose levels of 30 mg/kg and higher removed 93 per cent of mucosal stages of Trichonema spp., while doses of 60 mg/kg removed 83 per cent and 89 per cent of the migrating larvae of S. vulgaris and S. edentatus respectively.
mesh_terms: D000818:Animals; D001011:Aorta / Q000469:parasitology; D001562:Benzimidazoles / Q000627:therapeutic use*; D005273:Fenbendazole / Q000627:therapeutic use*; D006736:Horses; D007420:Intestine, Large / Q000469:parasitology; D013319:Strongyle Infections, Equine / Q000188:drug therapy* / Q000469:parasitology
chemical_list: D001562:Benzimidazoles; D005273:Fenbendazole