Neurologic complications following the treatment of human Babesia microti infection with diminazene aceturate.
A 65-year-old man infected with Babesia microti failed to respond to therapy with oral chloroquine phosphate. He was then successfully dreated with diminazene aceturate, an experimental anti-protozoal agent. After his recovery from babesiosis, the patient developed acute idiopathic polyneuritis (Landry-Guillain-Barré Syndrome), which was probably related to his diminazene therapy.
D000368:Aged; D000578:Amidines / Q000009:adverse effects*; D000818:Animals; D001404:Babesiosis / Q000188:drug therapy*; D002738:Chloroquine / Q000627:therapeutic use; D004133:Diminazene / Q000009:adverse effects*; D006801:Humans; D008297:Male; D011115:Polyneuropathies / Q000139:chemically induced*
D000578:Amidines; D002738:Chloroquine; D004133:Diminazene