[Antithrombotic agents for the prevention of thromboses during infraclavicular vena cava catheterizaiton].
To study the suppressibility of thrombosis due to central venous catheter phlebographically, groups of 25 patients were given low-dose-heparin, dextran 70 or salicylate (initial application preoperatively). The catheter was inserted for 6 to 8 days. As a control group 25 patients received no antithrombotic medication whatsoever. Of these cases 35% showed evidence of thrombus formation. In comparison only the patients with salicylate showed a significant reduction of catheter-induced thrombosis by 67%. By comparing the heparin to the control group  the total of thrombotic formations when planimetrically assessed results in a ration of 1:12, which is superior to dextran and salicylate.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001241:Aspirin / Q000627:therapeutic use; D002404:Catheterization / Q000009:adverse effects*; D003911:Dextrans / Q000627:therapeutic use; D005260:Female; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D013350:Subclavian Vein; D013927:Thrombosis / Q000517:prevention & control*
D003911:Dextrans; D006493:Heparin; D001241:Aspirin
Antithrombotika zur Prophylaxe der Begleitthrombosen bei infraklavikulären Vena-Cava-Kathetern.