title: [Treatment of diabetes during pregnancy with Des-Phe insulin: preliminary results (author's transl)].
abstract: Seven pregnant diabetics were treated with Des-Phe insulin (Hoe 01-S and Hoe 02-S). Daily blood glucose profiles were obtained for 7 to 32 weeks, a total of 4182 measurements. The blood glucose level was well controlled with the insulin preparation. Postprandial blood-glucose increase was counteracted so that even one hour after food the preprandial blood sugar concentration had been reached (Des-Phe insulin Hoe 01-S). This ensured normal carbohydrate metabolism during pregnancy. There were no side effects or skin allergies. The pregnancy proceeded uneventfully in all patients resulting in seven normal infants.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006946:Hyperinsulinism / Q000517:prevention & control; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000517:prevention & control; D007328:Insulin / Q000627:therapeutic use*; D007330:Insulin Antibodies; D010649:Phenylalanine; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000628:therapy*
chemical_list: D007328:Insulin; D007330:Insulin Antibodies; D010649:Phenylalanine
vernacular_title: Behandlung von Diabetikerinnen während der Schwangershcaft mit Des-Phe-Insulin Erster Erfahrungsbericht.