title: Bilayer lipid membranes (BLM) study of antigen-antibody interactions.
abstract: Previous work of del Castillo and co-workers has shown that bilayer lipid membranes (BLM) can be used as transducers for detection of antigen-antibody reactions. The present experiments extend the previous work by incorporating complement into the BLM system. The results indicate that the antigen-antibody complex or the complement has no ability to affect the BLM system separately, but when carefully combined they will destabilize the BLM as a tool for investigating immunological reactions is suggested.
mesh_terms: D000906:Antibodies; D000936:Antigen-Antibody Complex; D000941:Antigens; D002784:Cholesterol; D003165:Complement System Proteins; D004553:Electric Conductivity; D006801:Humans; D007700:Kinetics; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D012709:Serum Albumin; D012710:Serum Albumin, Bovine
chemical_list: D000906:Antibodies; D000936:Antigen-Antibody Complex; D000941:Antigens; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D012709:Serum Albumin; D012710:Serum Albumin, Bovine; D003165:Complement System Proteins; D002784:Cholesterol