title: [Bile acid derivatives with antimicrobial activity].
abstract: A series of condensation products of cholic and dehydrocholic acids with (L)-aminoacids was prepared and tested in vitro for antimicrobial activity. The derivatives of cholic acid with basic aminoacids showed significant activity, especially marked when (L)-arginine was the condensed aminoacid.
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D002793:Cholic Acids / Q000138:chemical synthesis* / Q000494:pharmacology; D003685:Dehydrocholic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology
chemical_list: D000596:Amino Acids; D000900:Anti-Bacterial Agents; D002793:Cholic Acids; D003685:Dehydrocholic Acid
vernacular_title: Derivati di acidi biliari ad attività antimicrobica.