[The behaviour of visually evoked potentials (VEP) in schizophrenia under gradually rising doses of fluphenazine dihydrochloride (author's transl)].
The paper describes a study of visually evoked potentials (VEP) during 50 days in a schizophrenic female patient to whom we administered increasing dosages (from 150 mg up to 600 mg) and afterwards progressively decreasing ones (from 600 mg to 20 mg) of 10-(3-[4-(2-hydroxyethyl)-1-piperazinyl]-propyl)-2-trifluoromethylphenothiazine (fluphenazine-dihydrochloride). We tried to establish a relation between the aspect of latencies and form of curves and the dosages. We also discussed a possible correspondence between VEP and psychopathological changes.
D005071:Evoked Potentials / Q000187:drug effects*; D005260:Female; D005476:Fluphenazine / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D012559:Schizophrenia / Q000188:drug therapy / Q000503:physiopathology*; D014793:Visual Cortex / Q000187:drug effects* / Q000503:physiopathology
D005476:Fluphenazine
Das Verhalten der visuell evozierten Potentiale (VEP) bei Schizophrenie unter allmählich erhöhten Dosen von Fluphenazin-dihydrochlorid.