title: [Inactivated saponin vaccine against salmonellal abortion in sheep].
abstract: An inactivated saponine vaccine is prepared from five highly immunogenic Salmonella abortus ovis strains, selected by means of a biological test on white rats. Saline was used as a diluent of the vaccine, with the addition of 30 per cent glycerine, 0.012 per cent saponine and 0.1 per cent propiolactone. The optimum immunization dose of 5 cm3 is injected singly subcutaneously behind the elbow, two and a half months after impregnation. The vaccine is applied on infected farms before the disease occurs. The cellular-humoral immunity, which forms 14 days after the injection, lasts 4--5 months and protects the sheep against salmonellosis abortion.
mesh_terms: D000034:Abortion, Veterinary / Q000517:prevention & control*; D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage* / Q000302:isolation & purification; D004341:Drug Evaluation / Q000662:veterinary; D005260:Female; D011247:Pregnancy; D012475:Salmonella / Q000276:immunology; D012481:Salmonella Infections, Animal / Q000517:prevention & control*; D012503:Saponins; D012756:Sheep; D012757:Sheep Diseases / Q000517:prevention & control*; D014611:Vaccination / Q000662:veterinary
chemical_list: D001428:Bacterial Vaccines; D012503:Saponins
vernacular_title: Inaktivirana saponinova vaksina protiv salmonelozniia abort po ovtsete.