Cerebral complications of angiography for transient ischemia and stroke: prediction of risk.
We examined the records of 147  consecutive patients studied by femoral catheterization to identify factors contributing to angiographic risk in cerebrovascular disease. Cerebral complications occurred in 12.2 percent and were permanent in 5.2 percent. Computer-assisted multivariate analysis of 21 possible risk factors was done. Two of these risk factors correlated strongly with increased risk: number of previous transient ischemic attacks (TIAs) (p less than 0.001), and the presence of arterial stenosis of greater than 90 percent (p less than 0.03). Risk factors of marginal significance were: diabetes, female sex, and number of selective injections. A discriminant function for estimation of risk was derived: D = [8 X number of TIAs] + [6 x number of arteries catheterized] + [14 if diabetic, 0 if not] + [11 if female, 0 if male]. When D was greater than 55, 77 percent of patients had a complication. When D was less than 55, 98 percent of patients had no complication. Unfortunately, patients in whom the study is most indicated tend to be those at greatest risk.
D000704:Analysis of Variance; D001161:Arteriosclerosis / Q000000981:diagnostic imaging; D001314:Auscultation; D001927:Brain Diseases / Q000209:etiology*; D002404:Catheterization / Q000009:adverse effects; D002533:Cerebral Angiography / Q000009:adverse effects* / Q000379:methods; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging*; D003287:Contrast Media / Q000009:adverse effects; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D002546:Ischemic Attack, Transient / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D012306:Risk; D013035:Spasm / Q000209:etiology; D014786:Vision Disorders / Q000209:etiology
D003287:Contrast Media