title: [Relationship between the sensitivity of the delayed agglutination test and synthetic detergents].
abstract: Residual amounts of detergents (Losk, Bio-73, Alka-lux, Bourgas, Bourgaslux, and Vero) in a concentration of 10-5 to 10-7 in physiologic saline can inhibit the agglutination titers by 3 to 5 degrees. This could mislead in the assessment of the reaction with regard to its diagnostic value. It is admitted that the inhibition produced is due to changes in the antibodies--drop in the total protein and light variations in all protein fractions as well as in the probable surface deterioration of the antigen, leading to its defective agglutinability. It is suggested to rinse more than five times all glassware that has been cleaned with detergents.
mesh_terms: D000371:Agglutination / Q000187:drug effects*; D000372:Agglutination Tests / Q000592:standards*; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis*; D002645:Chickens / Q000276:immunology; D003902:Detergents / Q000494:pharmacology*; D012475:Salmonella / Q000276:immunology*; D012756:Sheep / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D003902:Detergents
vernacular_title: Povliiavane chuvstvitelnostta na bavnata aglutinatsionna reaktsiia ot sintetichni pochistvashti preparati.