[Andrological characteristics in males with X-chromosomal pathology].
The authors examined 32 patients with Klinefelter's syndrome: 21 with chromatine-positive (the 1st group), 11 with chromatine-negative (the 2nd group). In contrast to the patients of the 2nd group an altered karyotype was revealed in patients of the 1st group (47/XXY, 46XY/47XXY, 48XXXY/49XXXXY). Hormonal examination revelaed hypoandrogenia with a relative hyperestrogenuria in the majority of the patients of the 1st and 2nd groups. However, patients of the 2nd group displayed a greater preservation of the reserve testicular function. Further clinical, endocrinological and cytogenetic studies of the Klinefelter's syndrome is necessary for its differential diagnosis and correction.
D015068:17-Ketosteroids / Q000652:urine; D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D004967:Estrogens / Q000652:urine; D005260:Female; D006801:Humans; D007713:Klinefelter Syndrome / Q000175:diagnosis*; D008297:Male; D010808:Physical Examination; D012727:Sex Characteristics; D012728:Sex Chromatin / Q000032:analysis; D013739:Testosterone / Q000652:urine; D014960:X Chromosome
D015068:17-Ketosteroids; D004967:Estrogens; D013739:Testosterone
Andrologischeskaia kharakteristika lits muzhskogo pola s X-khromosomnoĭ patologieĭ.