title: Immunological relationships and a genetic interpretation of major and minor acidic proteins in human parotid saliva.
abstract: Isoelectric focusing was performed on parotid salivas selected for their electrophoretic phenotypes of proline-rich acidic salivary proteins. Fractions encompassing narrow pH regions were pooled and examined by polyacrylamide  gel electrophoresis. Isoelectric focusing yielded partial purification of major and minor acidic proline-rich proteins which were subsequently compared by immunoelectrophoresis and double immunodiffusion against goat anti-human parotid saliva. Cross-reactivity without spurring between all fractions containing major Pr proteins in both immunoelectrophoresis and double immunodiffusion suggests that these proteins are immunologically very similar or identical.
mesh_terms: D000483:Alleles; D000818:Animals; D003429:Cross Reactions; D006041:Goats / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G; D010306:Parotid Gland / Q000276:immunology / Q000378:metabolism; D010641:Phenotype; D012463:Saliva / Q000276:immunology; D012471:Salivary Proteins and Peptides / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G; D012471:Salivary Proteins and Peptides