Urine solute excretion in growing low-birth-weight infants.
Fifteen thriving low-birth-weight infants who weighed less than 1,950 gm at birth were randomly selected to study the urine solute excretion on two milk-based proprietary formulas, SMA or Formula 4. The results showed that urine oxmolality rose progressively with increasing caloric concentration and was 78, 111, and 163 mOsm/kg H2O on 67, 80, and 100 kCal/dl SMA, respectively. Formula 4 gave rise to significantly higher urine osmolality (133 mOsm/kg H2O) than SMA, when fed at the same caloric density of 67 kCal/dl. Although the dependence of urine solute excretion on dietary load was confirmed, the rapidly growing low-birth-weight infant appears to incorporate a larger portion of potential urine solute into growing tissues, than is the case in the term infant.
D000818:Animals; D004044:Dietary Proteins / Q000378:metabolism; D004573:Electrolytes / Q000652:urine; D002149:Energy Intake; D006801:Humans; D007225:Infant Food; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008892:Milk / Q000378:metabolism*; D009584:Nitrogen / Q000652:urine; D009994:Osmolar Concentration; D012995:Solubility; D014556:Urine / Q000032:analysis*
D004044:Dietary Proteins; D004573:Electrolytes; D009584:Nitrogen