[Acute iridocyclitis, ankylosing spondylitis (Bechterew) and congenital tissue antigens (author's transl)].
The tiysue antigen HLA-B27 was present in 92.6% of 95 Swiss patients with classical ankylosing spondylitis. This tissue antigen is present in only 7.7% of healthy Swiss blood donors. 36% of all patients had one or several acute attacks of anterior uveitis. This usually follows the onset of joint symptoms. In 4% of the 95 patients the iritis was the first symptom. The combination of acute uveitis and ankylosing spondylitis with the tissue antigen HLA-B27 indicates that not only the spondylitis, but also the uveitis is in many cases genetically determined.
D000208:Acute Disease; D000328:Adult; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000235:genetics / Q000276:immunology; D014606:Uveitis, Anterior / Q000209:etiology* / Q000235:genetics / Q000276:immunology
D006680:HLA Antigens
Akute Iridozyklitis, Spondylitis ankylosans Bechterew und angeborene Gewebsantigene.