[Thin-layer chromatographic technic for the semiquantitative determination of hydroxyzine residues in animal material].
The solution behaviour of hydroxyzine in water and chloroform (in the strongly alkaline and the strongly acidic range) is utilized to extract it from animal material and to purify the extract. A concentration of 0.01 p.p.m. is detectable in liver, kidneys and muscular substance. 0.05 p.p.m. may be determined semiquantitatively by visual spot comparison. In milk, the detectable amount is 0.1 p.p.m. and 0.5 p.p.m. can be determined semiquantitatively. The recoveries of low concentrations of hydroxyzine are likely to be lower in milk samples than in organ samples.
D000818:Animals; D002417:Cattle; D002855:Chromatography, Thin Layer / Q000379:methods; D005504:Food Analysis; D006919:Hydroxyzine / Q000032:analysis*; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D008460:Meat / Q000032:analysis; D008892:Milk / Q000032:analysis
D006919:Hydroxyzine
Dünnschichtchromatographisches Verfahren zur semiquantitativen Bestimmung von Hydroxyzinrückständen in tierischem Material.