["Low triiodothyronine (T3) syndrome": "thyroxine (T4) euthyroidism" evidence (author's transl)].
As first described in serious systemic illnesses isolated decreased T3 plasma concentration was related to impaired peripheral conversion of T4, to T3 with preferential production of reverse T3 (rT3). A "low T3 syndrome" was seen in 47 out of 109 patients with extra-thyroidal diseases. Metabolic state, TSH and TSH responses to TRH were normal despite of low T3 concentration. Euthyroidism seems mainly due to T4 itself in these patients.
D000368:Aged; D000856:Anorexia Nervosa / Q000378:metabolism; D004038:Diet, Reducing / Q000009:adverse effects; D006801:Humans; D007037:Hypothyroidism / Q000378:metabolism; D007674:Kidney Diseases / Q000378:metabolism; D008103:Liver Cirrhosis / Q000378:metabolism; D009369:Neoplasms / Q000378:metabolism; D009765:Obesity / Q000378:metabolism; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood*; D014284:Triiodothyronine / Q000097:blood* / Q000502:physiology*; D014285:Triiodothyronine, Reverse / Q000502:physiology*
D014284:Triiodothyronine; D014285:Triiodothyronine, Reverse; D013972:Thyrotropin; D013974:Thyroxine
"Syndrome de basse T3": évidence d'une "euthyroïdie à T4".