Detection of low-level carbadox residues in animal feeds by high pressure liquid chromatography.
The high pressure liquid chromatographic (HPLC) method is capable of detecting from 1 to 0.024 ppm methyl 3-(2-quinoxalinyl-methylene)carbazate-N1,N4-dioxide (carbadox). Carbadox is extracted from the feed with 2% NH4OH in acetone, passed through a liquid-liquid partition, subjected to HPLC, and detected by using a 365 nm detector. No feed materials or other active drug ingredients produced false positive results.
D000821:Animal Feed / Q000032:analysis*; D000818:Animals; D002218:Carbadox / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D005506:Food Contamination / Q000032:analysis; D008722:Methods; D011810:Quinoxalines / Q000032:analysis*; D013552:Swine
D011810:Quinoxalines; D002218:Carbadox