[Comparative studies on pirbuterol, salbutamol and a placebo administered as an aerosol in asthmatic patients].
In a single blind cross-over study 12 patients with asthma received in randomised order aerosols of pirbuterol 400 micrograms, salbutamol 200 micrograms or placebo. Only 9 patients met the criteria and were taken into account for the statistical analysis, namely a stable reversible broncho-obstruction. Pirbuterol and salbutamol did induce a considerable bronchodilation. Both drugs had a similar activity and few side effects.
D000328:Adult; D000336:Aerosols; D000368:Aged; D000420:Albuterol / Q000008:administration & dosage*; D001249:Asthma / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000008:administration & dosage*; D004983:Ethanolamines / Q000008:administration & dosage*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos
D000336:Aerosols; D001993:Bronchodilator Agents; D004983:Ethanolamines; D010919:Placebos; C009118:pirbuterol; D000420:Albuterol
Vergelijkende studie met pirbuterol, salbutamol en een placebo toegediend onder vorm van gedoseerde aerosols bij astmatische patiënten.