Streptocerciasis: degeneration of adult Dipetalonema streptocerca in man following diethylcarbamazine therapy.
Thirty-three patients in Zaire with streptocerciasis were treated daily with diethylcarbamazine (DEC) for 21 days. Histopathologic studies of biopsy specimens with papules of skin established that during DEC treatment adult male and female Dipetalonema streptocerca die and degenerate. DEC may thus produce radical cures of streptocerciasis.
D000293:Adolescent; D000328:Adult; D002648:Child; D004049:Diethylcarbamazine / Q000627:therapeutic use*; D004153:Dipetalonema / Q000187:drug effects*; D004154:Dipetalonema Infections / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D005368:Filariasis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology
D004049:Diethylcarbamazine