[Human acrocentric chromosomal associations in old age].
Associations of satellite chromosome fibres of acrocentric chromosomes of the DD, GG and DG types were studied in persons aged from 80 to 114 years. It was found that the value of P (probability of joining of satellite fibres of two chromosomes in a group) is considerably less than the corresponding value for persons aged from 20 to 48 years. It is supposed that the decrease of the frequency of association at senile age is caused by heterochromatization of satellite fibres in the 13th and 14 chromosome pairs.
D000328:Adult; D000368:Aged; D000375:Aging; D002478:Cells, Cultured; D002901:Chromosomes, Human, 13-15 / Q000648:ultrastructure*; D002904:Chromosomes, Human, 21-22 and Y / Q000648:ultrastructure*; D005260:Female; D006570:Heterochromatin / Q000648:ultrastructure; D006801:Humans; D007962:Leukocytes / Q000648:ultrastructure; D008297:Male; D008677:Metaphase; D008875:Middle Aged
D006570:Heterochromatin
Assotsiatsii akrotsentricheskikh khromosom cheloveka v starcheskom vozraste.