Effect of systemic corticosteroids on antibody-forming cells in the eye and draining lymph nodes.
After the intracorneal injection of rabbit eyes with bovine gamma globulin, a systemically administered corticosteroid resulted in the following changes: (1) a reduction in the number of antibody-forming cells in the homolateral uveal tract and cornea; (2) a reduction in the ocular inflammatory response; and (3) a reduction in the number of antibody-forming cells in the draining lymph nodes, if high doses of corticosteroid were given.
D000818:Animals; D000906:Antibodies; D000921:Antibody-Producing Cells / Q000187:drug effects*; D001082:Aqueous Humor / Q000276:immunology; D007634:Keratitis / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology*; D008297:Male; D011817:Rabbits; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000494:pharmacology*; D014605:Uveitis / Q000276:immunology*; D014822:Vitreous Body / Q000276:immunology
D000906:Antibodies; D014222:Triamcinolone Acetonide