Effect of influenza vaccination on plasma phenytoin concentrations.
A mean decrease in plasma phenytoin concentrations of 11-14% (p less than 0.005) was observed in seven patients within 4 days after influenza vaccination. Possible mechanisms are discussed.
D004827:Epilepsy / Q000188:drug therapy; D006801:Humans; D007252:Influenza Vaccines; D008657:Metabolic Clearance Rate / Q000187:drug effects; D010672:Phenytoin / Q000097:blood*; D014611:Vaccination
D007252:Influenza Vaccines; D010672:Phenytoin