[Several mechanisms of acetylcholine participation in the processes of formation and fixation of temporary connections].
Microphoretic application of acetylcholine (ACH) to the neurones of the rabbit sensorimotor cortex elicits changes of spontaneous and evoked activity which do not correlate with one another and which persist up to two minutes after the end of ACH application. Following the formation of a defensive conditioned reflex to sound, the reactions to ACH in units involved in the formation of the temporary connection are intensified as compared with their reactions before conditioning and with reactions of those neurones which did not elaborate a temporary connection. The possible mechanisms of ACH participation in the processes of elaboration and fixation of temporary connections are discussed.
D000109:Acetylcholine / Q000494:pharmacology*; D000293:Adolescent; D000818:Animals; D001931:Brain Mapping; D003214:Conditioning, Classical / Q000187:drug effects*; D005071:Evoked Potentials; D005712:Galvanic Skin Response / Q000187:drug effects; D006801:Humans; D009044:Motor Cortex / Q000187:drug effects*; D011817:Rabbits; D011930:Reaction Time / Q000187:drug effects; D011999:Recruitment, Neurophysiological; D012154:Reticular Formation / Q000502:physiology; D013003:Somatosensory Cortex / Q000187:drug effects*; D013016:Sound
D000109:Acetylcholine
O nekotorykh mekhanizmakh uchastiia atsetilkholina v protsessakh formirovaniia i fiksatsii vremennykh sviazeĭ.