Analysis of intrafamilial correlations, serum levels of IGM and the human X-chromosome.
The serum concentrations of immunoglobulin M (IgM) were measured in a sample of 93 monozygotic twin pairs, their spouses, and their offsprings. The hypothesis that the human X chromosome carries genes that control the levels of IgM was tested with two different approaches neither one of which provided conclusive evidence to support the IgM X-linked gene hypothesis.
D005260:Female; D008040:Genetic Linkage; D006801:Humans; D007075:Immunoglobulin M / Q000235:genetics*; D008297:Male; D011247:Pregnancy; D012730:Sex Chromosomes; D014427:Twins; D014430:Twins, Monozygotic; D014960:X Chromosome
D007075:Immunoglobulin M