title: The effect of parathyroid hormone and vitamin D3 metabolites on CaBP synthesis by embryonic duodenum, in vitro.
abstract: Embryonic chick duodena were incubated, in vitro, for two days in the presence of vitamin D analogues and metabolites and the ability of PTH to potentiate the vitamin-D-dependent synthesis of CaBP measured. PTH potentiated CaBP synthesis in the presence of vitamin D3, 25-OH-D3, 1 alpha-OH-D3, DHT, and 1,25(OH)2D3. The synthesis of CaBP was directly related to the log of the meddium PTH concentration over the range 1 x 10(-8) M to 5 x 10(-7) M.
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002352:Carrier Proteins / Q000096:biosynthesis*; D002642:Chick Embryo; D004100:Dihydroxycholecalciferols / Q000494:pharmacology; D004357:Drug Synergism; D004386:Duodenum / Q000196:embryology / Q000378:metabolism*; D006887:Hydroxycholecalciferols / Q000494:pharmacology*; D009924:Organ Culture Techniques; D010281:Parathyroid Hormone / Q000494:pharmacology*
chemical_list: D002352:Carrier Proteins; D004100:Dihydroxycholecalciferols; D006887:Hydroxycholecalciferols; D010281:Parathyroid Hormone; D002118:Calcium