title: [A study of the natural evolution of hypertrophic obstructive cardiomyopathy. Analysis of 100 cases (authors' transl)].
abstract: The authors present a study of the course of hypertrophic obstructive cardiomyopathy (C.I.O.), diagnosed both through noninvasive (52) and invasive (48 cases) techniques, in 100 patients. The average period of observation (prospective and retrospective) was 8.2 years; in 68 cases prospective inquiries were carried out over an average period of 4.6 years. In 80% of the cases the first symptoms occurred when the patient was under 40, while the first diagnosis and period of observation usually took place between the ages of 20 and 50. The results of this study confirm that CIO is an illness with a slow evolution; the following facts emerge: a) considerable stability of the symptoms; b) low yearly mortality rate (1.8%); c) high rate of survival 10 years after the first onset of the symptoms. The most frequent cause of death is usually sudden, which leads to the supposition that one of the most important elements for prognosis is the identification and treatment of arrhythmias.
mesh_terms: D000787:Angina Pectoris / Q000209:etiology; D001145:Arrhythmias, Cardiac / Q000209:etiology; D009202:Cardiomyopathies / Q000150:complications / Q000453:epidemiology / Q000401:mortality / Q000473:pathology; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012189:Retrospective Studies; D013575:Syncope / Q000209:etiology
vernacular_title: Evoluzione naturale della cardiomiopatia ipertrofica ostruttiva. Analisi di 100 casi.