Detoxification reactions in isolated hepatocytes. Role of glutathione peroxidase, catalase, and formaldehyde dehydrogenase in reactions relating to N-demethylation by the cytochrome P-450 system.
D000445:Aldehyde Oxidoreductases / Q000378:metabolism*; D000818:Animals; D002374:Catalase / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D005557:Formaldehyde; D005561:Formates; D005979:Glutathione Peroxidase / Q000378:metabolism*; D006861:Hydrogen Peroxide; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D010084:Oxidation-Reduction; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism*; D010544:Peroxidases / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats
D005561:Formates; D005557:Formaldehyde; D003577:Cytochrome P-450 Enzyme System; D006861:Hydrogen Peroxide; D010544:Peroxidases; D002374:Catalase; D005979:Glutathione Peroxidase; D000445:Aldehyde Oxidoreductases; D010089:Oxidoreductases, N-Demethylating; D010634:Phenobarbital