XY gonadal dysgenesis associated with hGH and gonadotrophin deficiencies.
A girl of remarkably short stature, referred for investigation with the diagnosis of gonadal dysgenesis and the finding of a male karyotype, proved to be deficient in growth hormone and gonadotrophin secretion, and was treated with growth and sex hormones. It was concluded that this case demonstrates an apparently casual coincidence of pituitary insufficiency with XY gonadal dysgenesis, evidently the first to be reported.
D000293:Adolescent; D000328:Adult; D003241:Consanguinity; D004393:Dwarfism, Pituitary / Q000150:complications* / Q000235:genetics / Q000503:physiopathology; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006065:Gonadotropins, Pituitary / Q000172:deficiency*; D013006:Growth Hormone / Q000172:deficiency*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D011581:Psychological Tests; D014424:Turner Syndrome / Q000150:complications* / Q000235:genetics / Q000503:physiopathology; D014998:Y Chromosome
D006065:Gonadotropins, Pituitary; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013006:Growth Hormone