Stable and transmissible dicentric chromosome with terminal centromeres in ascites cell of mouse sarcoma 180.
The occurrence of a stable and transmissible dicentric chromosome with 2 terminal centromers has been reported in the ascites form of mouse sarcoma 180 cells which is chromosomally hypotetraploid. The number of such dicentrics is 2 in all endoreduplicated cells. The probable mode of anaphase separation of the dicentric has been discussed.
D000782:Aneuploidy; D000818:Animals; D001201:Ascites; D002503:Centromere / Q000648:ultrastructure; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D051379:Mice; D008938:Mitosis; D012510:Sarcoma 180 / Q000235:genetics*