[Effect of psychotomimetics and haloperidol on head twitching following alcohol withdrawal in mice].
After ethanol withdrawal dependent mice exhibited head twitching. The frequency of head-twitches was decreased by LSD and mescaline in a dose-dependent manner and increased by small doses of haloperidol and physostigmine. LSD antagonized the potentiating effects of haloperidol and physostigmine. The incidence of head-twitches after intracerebral injections of 5-HT in naive mice was lessened by LSD. The involvement of dopaminergic, serotoninergic, and cholinergic transmission systems in the action of psychotomimetics is discussed.
D000818:Animals; D000431:Ethanol; D006213:Hallucinogens / Q000627:therapeutic use*; D006220:Haloperidol / Q000037:antagonists & inhibitors / Q000627:therapeutic use*; D006801:Humans; D008238:Lysergic Acid Diethylamide / Q000627:therapeutic use; D008297:Male; D008635:Mescaline / Q000627:therapeutic use; D051379:Mice; D010830:Physostigmine / Q000037:antagonists & inhibitors / Q000627:therapeutic use; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy*; D014202:Tremor / Q000188:drug therapy*
D006213:Hallucinogens; D000431:Ethanol; D008238:Lysergic Acid Diethylamide; D010830:Physostigmine; D006220:Haloperidol; D008635:Mescaline
Die Wirkung von Psychotomimetika und Haloperidol auf das Kopfzucken nach Alkoholentzug bei Mäusen.