Effect of a hydrocholeretic agent (Zanchol) on sterol metabolism in rats.
The keto acid, gamma-oxo-gamma-(8-fluoranthene)butyric acid (Zanchol) markedly alters sterol metabolism in rats. It stimulates cholesterol and bile acid synthesis and decreases cholesterol absorption.
D000818:Animals; D001647:Bile Acids and Salts / Q000096:biosynthesis; D002087:Butyrates / Q000494:pharmacology; D002756:Cholagogues and Choleretics / Q000494:pharmacology*; D002784:Cholesterol / Q000096:biosynthesis / Q000378:metabolism*; D002793:Cholic Acids / Q000494:pharmacology*; D005449:Fluorenes / Q000494:pharmacology*; D008297:Male; D051381:Rats
D001647:Bile Acids and Salts; D002087:Butyrates; D002756:Cholagogues and Choleretics; D002793:Cholic Acids; D005449:Fluorenes; D002784:Cholesterol; C011826:florantyrone