[Assessment of the biological condition of a nonsterile preparation of cerebral dura mater during long-term storage in a formalin solution].
An allogeneic cerebral dura mater prepared under nonsterile conditions will become fully sterilized after 48 hours of storage in a 0.75% formalin solution. The long-term (up to 3 years) conservation of this tissue in the above mentioned solution preserves it in a condition permitting transplantation. The experimental transplantation of such tissue results in making the subdural space airtight. This occurs primarily because of the adhesion of the edges of the donor and recipients dura mater in the area of the defect as a result of aseptic inflammation with subsequent resolution and replacement of the transplant with the connective tissue of a similar structure with the dura mater.
D000328:Adult; D000818:Animals; D004285:Dogs; D004388:Dura Mater / Q000032:analysis / Q000637:transplantation; D005557:Formaldehyde; D006801:Humans; D006909:Hydroxyproline / Q000032:analysis; D008297:Male; D008875:Middle Aged; D011506:Proteins / Q000032:analysis; D013997:Time Factors; D014021:Tissue Preservation; D014183:Transplantation, Heterologous; D014184:Transplantation, Homologous
D011506:Proteins; D005557:Formaldehyde; D006909:Hydroxyproline
Otsenka biologicheskogo sostoianiia nesteril'no zagotovlennoĭ tverdoĭ mozgovoĭ obolochki v protsesse ee dlitel'nogo khraneniia v rastvore formalina.