title: Concepts leading to the development of an anti-ischemic drug. Introductory remarks.
mesh_terms: D003327:Coronary Disease / Q000188:drug therapy / Q000503:physiopathology*; D003401:Creatine / Q000031:analogs & derivatives / Q000627:therapeutic use; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D009200:Myocardial Contraction / Q000187:drug effects; D009336:Necrosis / Q000503:physiopathology
chemical_list: C100173:creatinol phosphate; D003401:Creatine