title: [Relationship between sex and the development and course of experimental chronic alcoholism].
abstract: The existence of sex differences in the development and course of experimental alcoholism in sexually mature rats (with 20 individual animals of each sex) was established. With formation of preference to a 8% ethanol solution as against water, with free access of the animals to the liquids, this process by its speed is shown to proceed quicker in males, but the females display a greater degree of preference. Moreover, the females manifest a greater lability with respect to the fortifying properties of ethanol. In framing the preference the presence of a second animal of the same or the other sex leads to a greater consumption of ethanol by the females than by males. On a repeated offering of ethanol following its cancellation the renewed preference of ethanol to water occurs in females quicker and more intensively than in males.
mesh_terms: D000437:Alcoholism / Q000453:epidemiology*; D000818:Animals; D005260:Female; D006801:Humans; D008297:Male; D051381:Rats; D012737:Sex Factors
vernacular_title: Osobennosti formirovaniia i techeniia éksperimental'nogo khronicheskogo alkogolizma v zavisimosti ot pola.