Lymphatic abnormalities in Noonan syndrome: A case report.
Lymphatic abnormalities are not generally recognized as part of the Noonan syndrome. A child with this condition in whom unique and widespread lymphatic abnormalities were demonstrated by lymphography is described. Both T and B lymphocytes were detected in chylous fluid drained from the thorax. In addition, the child was found to have a protein-losing enteropathy and cardiovascular defects. The clinical spectrum of the Noonan syndrome may include animalies of the lymphatic system.
D006328:Cardiac Catheterization; D002648:Child; D002916:Chylothorax / Q000150:complications; D005260:Female; D006801:Humans; D008208:Lymphatic System / Q000002:abnormalities*; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000502:physiology; D008220:Lymphography; D009634:Noonan Syndrome / Q000150:complications*; D011666:Pulmonary Valve Stenosis / Q000150:complications; D011947:Receptors, Antigen, B-Cell
D011947:Receptors, Antigen, B-Cell