[Variations of chlorides and bicarbonates in pancreatic juice in response to increasing doses of secretin and cholecystokinin].
Sequential changes in chloride and bicarbonate concentrations in pancreatic juice were evaluated after gradually increased doses of: 1) synthetic secretin in men 2) natural secretin in dogs 3) natural CCK in dogs. The results suggest that the increase in bicarbonate concentration is accompanied by a proportional chloride concentration decrease. The total anionic concentration is constant and it is not affected by different hormonal stimulation.
D000328:Adult; D000818:Animals; D001639:Bicarbonates / Q000378:metabolism*; D002712:Chlorides / Q000378:metabolism*; D002766:Cholecystokinin / Q000494:pharmacology*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D006801:Humans; D010189:Pancreatic Juice / Q000187:drug effects / Q000378:metabolism*; D012633:Secretin / Q000494:pharmacology*
D001639:Bicarbonates; D002712:Chlorides; D012633:Secretin; D002766:Cholecystokinin
"Variazioni del cloro e dei bicarbonati nel succo pancreatico in risposta a dosicrescenti di secretina o colecistochinina".