[Influence of nystatine, a polyene antibiotic, on the formation of complex-bound sterols and the formation of conidia by Coprinus cinereus (author's transl)].
In contrary to the wild strain, a monocaryotic mutant of Coprinus cinereus (basidiomycete) does not contain hydrosoluble, complex-bound sterols. Under nystatine-treatment, however, the mutant is induced to produce this kind of stereols in abundance. Furthermore, nystatine highly increases sporulation of the mutant and decreases sporulation of the wild strain.
D000363:Agaricales / Q000378:metabolism*; D003302:Coprinus / Q000187:drug effects / Q000378:metabolism*; D007700:Kinetics; D009154:Mutation; D009761:Nystatin / Q000494:pharmacology*; D013045:Species Specificity; D013261:Sterols / Q000096:biosynthesis*; D013997:Time Factors
D013261:Sterols; D009761:Nystatin
Influence de la nystatine, un antibiotique polyénique, sur la formation des stérols liés par complexes et sur la conidiation du Coprinus cinereus