The influence of succinylcholine on the duration of pancuronium neuromuscular blockade.
Question has been raised as to whether the use of succinylcholine (SCh) to facilitate endotracheal intubation might influence the duration of subsequently used pancuronium. The authors studied the duration of pancuronium in 67 adult patients by measuring muscle response to nerve stimulation. Thirty-seven of these patients were given prior SCh while the remaining 30 were not. No significant difference in the duration of pancuronium block was found between these 2 groups.
D000328:Adult; D004347:Drug Interactions; D004558:Electric Stimulation; D006801:Humans; D009119:Muscle Contraction / Q000187:drug effects; D009469:Neuromuscular Junction / Q000187:drug effects*; D010197:Pancuronium / Q000494:pharmacology*; D011229:Preanesthetic Medication; D013390:Succinylcholine / Q000494:pharmacology*; D013997:Time Factors; D014459:Ulnar Nerve / Q000502:physiology
D013390:Succinylcholine; D010197:Pancuronium