Persistent measles virus infection in a calf kidney cell line. Note III. Cellular alterations in the selected chronically infected K-2 cell line.
Marked morphological, growth and chromosome alterations pointing to in vitro cellular transformation were made evident in a selected calf kidney cell line (K-2) chronically infected with measles virus. The transformed cell line released infectant virus and had no oncogenic potential for the hamster.
D000818:Animals; D002417:Cattle; D002472:Cell Transformation, Viral; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D003588:Cytopathogenic Effect, Viral; D066298:In Vitro Techniques; D007668:Kidney; D008459:Measles virus; D014776:Virus Cultivation