Some behavioral effects of SP 6-11 hexapeptide C-terminal of substance P injected into the cerebral ventricles in rats.
The effects of the peptide SP 6-11 injected into the lateral brain ventricle in chronic rats on the alimentary behavior in a maze and some spontaneous exploratory reactions were studied. It was shown that the peptide SP 6-11 in doses ranging from 50 to 500 pmol increased only locomotor activity and did not change a number of correct trials in a maze.
D000818:Animals; D002552:Cerebral Ventricles; D007278:Injections, Spinal; D008297:Male; D009043:Motor Activity / Q000187:drug effects*; D010446:Peptide Fragments; D051381:Rats; D013373:Substance P / Q000008:administration & dosage / Q000494:pharmacology*
D010446:Peptide Fragments; D013373:Substance P