[Pararenal angiosarcoma as a manifestation of sexual dimorphism in carcinogenesis].
Pararenal angiosarcoma developed in 42% of CBA male mice injected subcutaneously 1.2-dimethyl hydrazine (DMH) in a dose of 8 mg/kg body weight within 30 weeks. None of 176 CBA female mice given the same treatment developed such tumors. Histologically, the tumors represented various angiosarcomas characterized by a marked invasive growth into the renal parenchyma.
D000818:Animals; D004127:Dimethylhydrazines; D006394:Hemangiosarcoma / Q000139:chemically induced* / Q000473:pathology; D007680:Kidney Neoplasms / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000473:pathology; D011110:Polymorphism, Genetic; D013997:Time Factors
D004127:Dimethylhydrazines
Pararenal'naia angiosarkoma kak proiavlenie polovogo dimorfizma v kantaserogeneze.