Haemorrhagic infarction of the myocardium in a newborn with haemoglobin H disease and erythroblastosis.
Extensive haemorrhagic myocardial infarction developed in a newborn, apparently as a result of anoxia due to erythroblastosis fetalis, associated with haemoglobin H disease. Acute massive myocardial infarction in the neonatal period is rare and usually is associated with congenital malformation of the heart or its blood supply. Neonatal myocardial infarction in the anatomically normal heart with normal coronary vessels, has been described in only 8 patients (1). The communication describes a newborn with acute haemorrhagic myocardial infarction due to anoxia believed to be caused by the combined effect of erythroblastosis fetalis and haemoglobin H disease.
D004899:Erythroblastosis, Fetal / Q000150:complications*; D005260:Female; D006447:Hemoglobin H; D006453:Hemoglobinopathies / Q000150:complications*; D006470:Hemorrhage / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology* / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D011247:Pregnancy
D006447:Hemoglobin H