[Biological properties of the mumps virus. Behavior using the T50 marker].
The authors studied the behaviour of 11 mumps virus strains or variants including the thermolabile standard Jeryl Lynn strain under thermal charge (50 degrees C/30 min). Varants were obtained from the Soviet vaccinal strains Leningrad-3 by cultivation under various conditions. Incubation temperature and cellular substrate played an important role therein. Variants with various behaviour in the marker T50 resulted. It was found that passages at 32 degrees C at limited dilutions as well as those on chick embryos or in cultures of chicken fibroblasts increased their thermolability. Possible correlations between their behaviour in the marker T50 and the degree of di attenuation are discussed. (Ta)
D000650:Amnion; D000818:Animals; D002478:Cells, Cultured; D002642:Chick Embryo; D003470:Culture Media; D004285:Dogs; D005347:Fibroblasts; D006358:Hot Temperature; D006801:Humans; D007668:Kidney; D009109:Mumps virus / Q000235:genetics / Q000502:physiology*; D014613:Vaccines, Attenuated; D014774:Virulence; D014779:Virus Replication
D003470:Culture Media; D014613:Vaccines, Attenuated
Biologische Eigenschaften des Mumpsvirus. Das Verhalte im T50-Marker.