Evaluation of the fibrinogen analyzer.
The fibrinogen analyzer, a newly introduced instrument for plasma fibrinogen assay, was evaluated for its clinical use. Fibrinogen was assayed based on the automated measurement of absorbance changes of fibrinogen clotting by thrombin. High reproducibility and close correlation with the phenol method were observed. Concentrations of heparin below 1.25 mu/ml had minimal effects on the fibrinogen assay using the fibrinogen analyzer. Free hemoglobin below 400 mg/dl and bilirubin with a concentration less than 4 mg/dl had no significant effects on the fibrinogen values. This instrument is highly recommended for plasma fibrinogen assay in clinical laboratories.
D000818:Animals; D001663:Bilirubin; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D005069:Evaluation Studies as Topic; D005340:Fibrinogen; D006454:Hemoglobins; D006493:Heparin; D006801:Humans; D010636:Phenols
D006454:Hemoglobins; D010636:Phenols; D005340:Fibrinogen; D006493:Heparin; D001663:Bilirubin