Gonadal malignancy and 46, XY karyotype in a true hermaphrodite.
A case of true hermaphroditism associated with gonadoblastoma and dysgerminoma is reported. The patient had a 46, XY karyotype. The possible significance of the Y chromosome in the development of gonadal tumors and the histogenetic problems of gonadoblastoma are also discussed.
D000328:Adult; D012734:Disorders of Sex Development / Q000150:complications* / Q000601:surgery; D004407:Dysgerminoma / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology; D010053:Ovary / Q000473:pathology; D012729:Sex Chromosome Aberrations; D013736:Testicular Neoplasms / Q000150:complications* / Q000473:pathology; D013737:Testis / Q000473:pathology