[Effect of polyethyelene glycol on proliferation of cultured Chinese hamster cells].
Chinese hamster cells in suspension were treated with PEG 4000 for 20 min. It was found that cell size began to diminish already when a 5% PEG solution was used, and reached the minimal value in a 20% PEG solution. A pronounced cell death was observed when PEG concentration exceeded 20%, but cells that survived retained their proliferation potential. It is concluded that the cell death results from hypoosmotic shock when cell suspension in PEG solution is diluted.
D000818:Animals; D002478:Cells, Cultured; D006224:Cricetinae; D004305:Dose-Response Relationship, Drug; D005347:Fibroblasts / Q000187:drug effects*; D008938:Mitosis / Q000187:drug effects*; D009997:Osmotic Pressure; D011092:Polyethylene Glycols / Q000494:pharmacology*
D011092:Polyethylene Glycols
Vliianie poliétilenglikolia na proliferatsiiu kul'tiviruemykh kletok kitaĭskogo khomiachka.