title: Metabolic fate of timepidium bromide (SA-504)--Unstable metabolities in the rats.
abstract: The colored substances excreted in bile or urine have bee investigated after adminstration of a high dose of SQ-504 to rats. A reddish-violet colored substance and a bluish-violet colored substance were dominant. Their chemical structures were not assigned because of their small quantity and instability. It was recognized that the colored substances were metabolites of SA-504 from the studies with 3H and 14C labelled SA-504 and the derivatives of SA-504.
mesh_terms: D000818:Animals; D001646:Bile / Q000032:analysis; D002250:Carbon Radioisotopes; D055598:Chemical Phenomena; D002621:Chemistry; D010860:Pigments, Biological / Q000032:analysis / Q000302:isolation & purification / Q000652:urine; D010880:Piperidines / Q000138:chemical synthesis / Q000378:metabolism*; D051381:Rats; D013329:Structure-Activity Relationship; D013876:Thiophenes / Q000138:chemical synthesis / Q000378:metabolism*; D014316:Tritium
chemical_list: D002250:Carbon Radioisotopes; D010860:Pigments, Biological; D010880:Piperidines; D013876:Thiophenes; D014316:Tritium; C001739:timepidium bromide