title: Digital contracture deformity after implantation of a silicone prosthesis: light and electron microscopic study.
abstract: Following the implantation of a silicone tendon prosthesis for reconstruction of a deep flexor tendon, an extensive, dense, contractile fibrosis developed rapidly. The resulting flexion deformity ultimately necessitated an amputation. The amputated specimen was examined by light and electron microscopy. A great many myofibroblasts were seen in the new tendon sheath, which, because of their contractile properties, probably caused the deformity.
mesh_terms: D003286:Contracture / Q000473:pathology*; D003599:Cytoskeleton / Q000648:ultrastructure; D005347:Fibroblasts / Q000648:ultrastructure; D005383:Finger Injuries / Q000601:surgery*; D005385:Fingers / Q000473:pathology; D006097:Granulation Tissue / Q000473:pathology; D006227:Hand Deformities, Acquired / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000648:ultrastructure; D011183:Postoperative Complications / Q000473:pathology*; D019736:Prostheses and Implants; D012828:Silicones; D013708:Tendon Injuries / Q000601:surgery*
chemical_list: D012828:Silicones