title: A comparison between the morphologic changes in the livers of hamsters and rats after galactosamine treatment and their correlation with altered serum transaminase levels.
abstract: Galactosamine caused changes in the livers of rats that were similar to those seen in human viral hepatitis. In hamsters the changes were characteristic of a typical toxic hepatitis. The response by the liver to galactosamine was very variable in both the rat and the hamster and there was a degree of correlation between the raised transaminase levels and the liver cell damage.
mesh_terms: D000818:Animals; D056486:Chemical and Drug Induced Liver Injury; D006224:Cricetinae; D005688:Galactosamine / Q000009:adverse effects / Q000494:pharmacology*; D008099:Liver / Q000166:cytology* / Q000187:drug effects; D008297:Male; D051381:Rats; D000637:Transaminases / Q000097:blood*
chemical_list: D005688:Galactosamine; D000637:Transaminases