Effects of cadium on growth, sexual development, and metabolism in female rats.
Female rats were exposed to cadmium by multiple intramuscular injections of 250 mug CaCl2 for 54 days. Activity and haircoat were affected, sores on the sites of injection and persistent diestrus were observed in the treated rats. Morphological examination of organs revealed a smaller weight and size in reproductive organs and pituitary, but enlargement of liver, spleen, and kidney. The ratic enzymatic demethylation activity.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002104:Cadmium / Q000097:blood / Q000494:pharmacology*; D004971:Estrus / Q000187:drug effects; D005260:Female; D006128:Growth / Q000187:drug effects*; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008660:Metabolism / Q000187:drug effects*; D009929:Organ Size / Q000187:drug effects; D011247:Pregnancy; D051381:Rats; D012741:Sexual Maturation / Q000187:drug effects*; D013154:Spleen / Q000033:anatomy & histology / Q000187:drug effects
D002104:Cadmium