title: Ophthalmic manifestations of visceral larva migrans.
abstract: Two patients had ocular manifestations of infestation with visceral larva migrans. In neither case did the eye involvement improve despite thiabendazole, local and systemic steroids, and cryotherapy. The lack of ocular response to treatment may be assumed to be because of organisms were already dead. Thiabendazole therapy is probably worth trying for early ophthalmic involvement with visceral larva migrans if the organism is still alive. In most cases the diagnosis of visceral larva migrans can be made with the help of the ELISA serum antigen determination so that enucleation of the eye will not be necessary for diagnostic purposes.
mesh_terms: D002675:Child, Preschool; D003452:Cryosurgery; D004797:Enzyme-Linked Immunosorbent Assay; D005128:Eye Diseases / Q000188:drug therapy / Q000469:parasitology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D007816:Larva Migrans, Visceral / Q000150:complications* / Q000175:diagnosis; D008297:Male; D012163:Retinal Detachment / Q000469:parasitology*; D013285:Strabismus / Q000469:parasitology*; D013827:Thiabendazole / Q000627:therapeutic use
chemical_list: D013827:Thiabendazole