[The use of different liver-protective substances in the course of antitubercular chemotherapy and their effectiveness in preventing and countering the appearance of metabolic and functional liver changes Clinico-statistical studies].
An open study was run on three groups of hospitalised 40 patients with medium to serious lung TB to evaluate the effectiveness of generic liver protector drugs, UDPG, and an association of UDPG-GSH in the prevention a nd hindrance of organic and metabolic-functional liver alterations in the course of chemotherapy. It was found that UDPG--particularly in association with GSH--gave highly significant results by comparison with generic protector drugs.
D000596:Amino Acids / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000009:adverse effects*; D005260:Female; D005978:Glutathione / Q000627:therapeutic use*; D006801:Humans; D008107:Liver Diseases / Q000209:etiology* / Q000517:prevention & control; D008110:Liver Extracts / Q000627:therapeutic use*; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*; D014532:Uridine Diphosphate Glucose / Q000627:therapeutic use*; D014535:Uridine Diphosphate Glucuronic Acid / Q000627:therapeutic use*; D014539:Uridine Diphosphate Sugars / Q000627:therapeutic use*; D014805:Vitamin B 12 / Q000627:therapeutic use*
D000596:Amino Acids; D000995:Antitubercular Agents; D008110:Liver Extracts; D014539:Uridine Diphosphate Sugars; D014535:Uridine Diphosphate Glucuronic Acid; D005978:Glutathione; D014805:Vitamin B 12; D014532:Uridine Diphosphate Glucose
Impiego di differenti sostanze di pertinenza epatica in corso di chemioterapia antitubercolare e loro efficacia nel prevenire e contrastare l'insorgenza di alterazioni metabolico-funzionali. Ricerca clinico-statistica.