Thin-layer chromatographic separation of the 3-O-methylated metabolites of noradrenaline.
The use of sodium borate impregnated thin-layer silica gel plates for the separation of noradrenaline and its 3-O-methylated metabolites is described. Its application to studies of the metabolism of tritiated I-noradrenaline by isolated tissues is illustrated for the rabbit uterus.
D000818:Animals; D002855:Chromatography, Thin Layer; D005260:Female; D006018:Glycols / Q000302:isolation & purification*; D066298:In Vitro Techniques; D008734:Methoxyhydroxyphenylglycol / Q000302:isolation & purification*; D009638:Norepinephrine / Q000302:isolation & purification* / Q000378:metabolism; D009647:Normetanephrine / Q000302:isolation & purification*; D011817:Rabbits; D014599:Uterus / Q000032:analysis / Q000378:metabolism; D014642:Vanilmandelic Acid / Q000302:isolation & purification*
D006018:Glycols; D009647:Normetanephrine; D008734:Methoxyhydroxyphenylglycol; D014642:Vanilmandelic Acid; D009638:Norepinephrine