The efficacy of fenbendazole in the control of immature strongyle infections in ponies.
The efficacy of fenbendazole against immature stages of Trichonema spp., Strongylus vulgaris and Strongylus edentatus was evaluated. Naturally infected 6 to 12 month old ponies were given single, oral doses of 0, 15, 30 and 60 mg/kg of body weight. A dose response relationship was noted between increasing dose levels and efficiency against larval trichonemes and migrating stages of S. vulgaris and S. edentatus. Dose levels of 30 mg/kg and higher removed 93 per cent of mucosal stages of Trichonema spp., while doses of 60 mg/kg removed 83 per cent and 89 per cent of the migrating larvae of S. vulgaris and S. edentatus respectively.
D000818:Animals; D001011:Aorta / Q000469:parasitology; D001562:Benzimidazoles / Q000627:therapeutic use*; D005273:Fenbendazole / Q000627:therapeutic use*; D006736:Horses; D007420:Intestine, Large / Q000469:parasitology; D013319:Strongyle Infections, Equine / Q000188:drug therapy* / Q000469:parasitology
D001562:Benzimidazoles; D005273:Fenbendazole