Familial occurrence of severe ulnar aplasia and lobster claw feet: a new syndrome.
In this paper we describe a previously unreported association of ulnar defect and lobster-claw deformity of the feet, occurring in four males belonging to two generations of the same family. Minor expression of the same ulnar reduction defect in female relatives suggests X-linked recessive inheritance, but an autosomal dominant with irregular expression cannot be excluded.
D000015:Abnormalities, Multiple / Q000235:genetics*; D000293:Adolescent; D005260:Female; D005528:Foot / Q000000981:diagnostic imaging; D005532:Foot Deformities, Congenital; D006801:Humans; D008297:Male; D010375:Pedigree; D011859:Radiography; D013577:Syndrome; D014457:Ulna / Q000002:abnormalities* / Q000000981:diagnostic imaging; D014960:X Chromosome