title: [Synthesis of radioactively labelled reproterol hydrochloride (author's transl)].
abstract: Synthesis of radioactively labelled 7-(3-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethylamino]-propyl)-theophylline (reproterol) as needed for pharmacokinetic examinations, is described. The 14C-malonic diethyl ester was proven to be the suitable starting compound. The synthesis of the tritium-labelled reproterol is briefly described.
mesh_terms: D001993:Bronchodilator Agents / Q000138:chemical synthesis; D002250:Carbon Radioisotopes; D055598:Chemical Phenomena; D002621:Chemistry; D007553:Isotope Labeling; D010627:Phenethylamines / Q000138:chemical synthesis*; D014316:Tritium; D014970:Xanthines / Q000138:chemical synthesis*
chemical_list: D001993:Bronchodilator Agents; D002250:Carbon Radioisotopes; D010627:Phenethylamines; D014970:Xanthines; D014316:Tritium
vernacular_title: Synthese von radioaktive markiertem Reproterol-hydrochlorid