title: Synthesis of some 2-styrylquinazoline derivatives structurally related to certain chemotherapeutic agents.
abstract: The synthesis of certain 2-styryl-4-arylaminoquinazolines having the general formula 1 is described. 4-Chloro-2-styrylquinazolines were prepared by chlorination of 2-styryl-4-quinazolones in benzene solution using phosphorus oxychloride and an excess of dimethylaniline. Reacting the chlorostyrylquinazolines with certain arylamines afforded 1.
mesh_terms: D000588:Amines; D055598:Chemical Phenomena; D002621:Chemistry; D005557:Formaldehyde; D010880:Piperidines; D011799:Quinazolines / Q000138:chemical synthesis*
chemical_list: D000588:Amines; D010880:Piperidines; D011799:Quinazolines; D005557:Formaldehyde