Topical mechlorethamine therapy for mycosis fungoides.
Patients with limited skin involvement by mycosis fungoides were treated with daily topical mechlorethamine. Seven of thirteen patients had a complete remission of diseases. Six of these seven experienced a contact dermatitis and four underwent a successful topical desensitization programme. The possible beneficial therapeutic effects of developing a contact allergy are discussed.
D000287:Administration, Topical; D003877:Dermatitis, Contact / Q000209:etiology; D003888:Desensitization, Immunologic; D005260:Female; D006801:Humans; D008297:Male; D008466:Mechlorethamine / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000188:drug therapy*; D012878:Skin Neoplasms / Q000188:drug therapy*
D008466:Mechlorethamine