Failure to obtain positive MEM tests in either cell-mediated immune conditions in the guinea-pig or in human cancer.
The macrophage electrophoretic mobility test described by Caspary and Field (1971) and modified by Pritchard et al. (1973) was investigated in various models of cell-mediated immune conditions in the guinea-pig and in cancer in man. No positive results were obtained in 92 guinea-pig experiments. Only 17 of 154 experiments on 74 patients gave definite positives in experiments with human cancer and a few positive results were obtained with normal healthy subjects.
D000818:Animals; D000941:Antigens; D000951:Antigens, Neoplasm; D002464:Cell Migration Inhibition; D004586:Electrophoresis; D006168:Guinea Pigs; D006801:Humans; D007111:Immunity, Cellular; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology*; D009369:Neoplasms / Q000276:immunology*
D000941:Antigens; D000951:Antigens, Neoplasm