Influence of somatostatin on blood pressure and plasma renin activity in the rat.
In the anaesthetized rat synthetic somatostatin can interfere with the renin-angiotensin system by increasing plasma renin activity and decreasing normal blood pressure or counteracting several types of experimental hypertension.
D000804:Angiotensin II / Q000494:pharmacology; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D006973:Hypertension / Q000139:chemically induced / Q000201:enzymology / Q000503:physiopathology; D006977:Hypertension, Renal / Q000201:enzymology / Q000503:physiopathology; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology; D051381:Rats; D012083:Renin / Q000097:blood* / Q000494:pharmacology; D013004:Somatostatin / Q000494:pharmacology*; D013997:Time Factors
D000804:Angiotensin II; D013004:Somatostatin; D012083:Renin; D009638:Norepinephrine