title: Cimetidine in the management of the Zollinger-Ellison syndrome.
abstract: The first case of the Zollinger-Ellison syndrome treated from the outset continuously for more than a year with the histamine H2-receptor antagonist cimetidine is reported. Symptomatic response has been dramatic and sustained, marked endoscopic improvement has been observed with healing of oesophageal, gastric and stomal ulcers.
mesh_terms: D000368:Aged; D002927:Cimetidine / Q000627:therapeutic use*; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D015043:Zollinger-Ellison Syndrome / Q000188:drug therapy*
chemical_list: D006146:Guanidines; D002927:Cimetidine