title: [Bacteriological and clinical evaluation of a dicloxacillin-ampicillin combination (author's transl)].
abstract: This paper presents the results of the bacteriological and clinical assessment of the dicloxacillin-ampicillin combination Totocillin. The bacteriological examinations show that a synergistic and hyperadditive effect particularly on Staphylococcus, but also on E. coli, Klebsiella-Enterobacter and in a few cases on Proteus spp. is achieved with the combination. Clinical experience in urinary tract infections evidences the good efficacy of the combined preparation, which on statistical evaluation proved to be significantly more active than ampicillin alone. Satisfactory therapeutic results with the combination were yielded also in infections not involving the urinary tract.
mesh_terms: D000667:Ampicillin / Q000494:pharmacology* / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000188:drug therapy*; D004009:Dicloxacillin / Q000494:pharmacology* / Q000627:therapeutic use; D004338:Drug Combinations; D006801:Humans; D008826:Microbial Sensitivity Tests; D014552:Urinary Tract Infections / Q000188:drug therapy
chemical_list: D004338:Drug Combinations; D000667:Ampicillin; D004009:Dicloxacillin
vernacular_title: Bakteriologische und klinische Bewertung einer Dicloxacillin-Ampicillin-Kombination.