[The presence of a hypothetical extracellular fraction in integral typhoid vaccines prepared on a semi-synthetic medium (author's transl)].
The Authors have carried out a research on the purpose of explain the action of a typhoid vaccines prepared on a semi-synthetic medium, which in preliminary tests on mice and men evinced good immunizing power. The tests now performed demonstrate that an acellular filtrate of the vaccine (obtained from 24 h old culture) showed have the characteristics of an exotoxin and developes a strong immunizing power.
D000818:Animals; D000907:Antibodies, Bacterial / Q000302:isolation & purification; D000917:Antibody Formation / Q000187:drug effects; D000942:Antigens, Bacterial / Q000302:isolation & purification; D003470:Culture Media; D005110:Extracellular Space / Q000276:immunology*; D051379:Mice; D011817:Rabbits; D014436:Typhoid-Paratyphoid Vaccines / Q000032:analysis* / Q000494:pharmacology
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D003470:Culture Media; D014436:Typhoid-Paratyphoid Vaccines
La presenza di una ipotetica frazione extracellulare in vaccini antitifici allestiti su terreno semisintetico.