[Uptake of retinol-C14 into liver mitochondrial membranes and erythrocyte stroma of albino rats on a vitamin A-free diet].
We have determined the incorporation of retinol-C14 into liver mitochondrial membranes and blood cell stroma in albino male Wistar strain rats, fed with a vitamin A deficient diet for 30, 60 and 90 days. At the end of the vitamin A deficient period, rats were kept fasting for 24 hours and then administered orally retinol-C14 (1,25 microC). They were divided into groups and killed after 3 hours, 3, 6, 12 days from the administration of retinol-C14. The incorporation is very high in one-month deficient rats, it decreases as the experimental period and the intervals after the administration of retinol-C14 grow longer.
D000818:Animals; D002250:Carbon Radioisotopes; D004912:Erythrocytes / Q000378:metabolism*; D008297:Male; D008930:Mitochondria, Liver / Q000378:metabolism*; D051381:Rats; D013997:Time Factors; D014801:Vitamin A / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D014802:Vitamin A Deficiency / Q000378:metabolism*
D002250:Carbon Radioisotopes; D014801:Vitamin A
Incorporazione di retinolo-C14 nelle membrane dei mitocondri epatici e nello stroma dei globuli rossi di ratti albini a dieta priva di vitamina A.