Mood change and magnesium. A possible interaction between magnesium and lithium?
Magnesium and lithium are chemically related. Magnesium is an essential ion in many enzyme systems and lithium is of value in the treatment of manic-depressive disease. A significant sex difference in mean plasma magnesium levels is reported in 44 depressed patients. It is suggested that further studies of magnesium metabolism are indicated and that they may provide a better understanding of manic-depressive disease and the mode of action of lithium.
D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy; D003863:Depression / Q000097:blood*; D005260:Female; D006801:Humans; D008094:Lithium / Q000494:pharmacology; D008274:Magnesium / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors
D008094:Lithium; D008274:Magnesium