The metabolic response to exercise in chronic alcoholics.
The metabolic response to steady exercise was studied in six chronic alcoholics and six normal control subjects. Higher concentrations of lactated and pyruvate were observed in the alcoholics during exercise and they also developed post-exercise ketosis. These changes were probably not due to reduced fitness of the alcoholics as the heart rates of both groups were similar. Alcoholics had lower levels of growth hormone during exercise compared with the controls suggesting that chronic alcohol consumption has a depressor effect on pathways regulating the release of growth hormone.
D000328:Adult; D000437:Alcoholism / Q000097:blood* / Q000503:physiopathology; D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005990:Glycerol / Q000097:blood; D013006:Growth Hormone / Q000097:blood; D006339:Heart Rate; D006801:Humans; D007659:Ketones / Q000097:blood; D007773:Lactates / Q000097:blood; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D011773:Pyruvates / Q000097:blood
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007659:Ketones; D007773:Lactates; D011773:Pyruvates; D013006:Growth Hormone; D005990:Glycerol