[Results of cellular immune reaction assessment under 5-fluorocytosine therapy].
In the judgment of cellular immune reactions with the help of LTT, taking into consideration age-specific variations in generalised mycoses negative and decreased results, respectively, are found after testing with PHA, PPD, in the mixed culture and with candidine. After overcoming of the generalisation of fungi the finding normalised. While using metabolites in other clinical pictures always a decrease of the cellular immune reaction is found, under treatment with 5-fluorocytosin in generalised mycoses no decrease of the transformation of lymphocytes is to be observed. Here after successful therapy even an adequate increase is shown. The examinations confirm the opinion that 5-fluorocytosin does not condition an influence on the function of the T-lymphocytes.
D002648:Child; D003596:Cytosine / Q000031:analogs & derivatives*; D005437:Flucytosine / Q000627:therapeutic use*; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D008213:Lymphocyte Activation; D009181:Mycoses / Q000188:drug therapy
D003596:Cytosine; D005437:Flucytosine
Ergebnisse der Beurteilung zellulärer Immunreaktionen unter der Behandlung mit 5-Fluorozytosin.