Changes of hormonal status in young mice by restricted caloric diet. Relation to lifespan extension. Preliminary results.
The maintainance of mice on a reduced caloric diet for 6 weeks starting from weaning time produces persistent changes in their hormonal status as reflected by differences in blood levels of gonadal and adrenal steroids. The changes might express a permanently different hypothalamic regulation. This might account for a prolongation of their life span.
D000375:Aging; D000818:Animals; D003345:Corticosterone / Q000097:blood; D004032:Diet; D004958:Estradiol / Q000097:blood; D005260:Female; D006728:Hormones / Q000097:blood*; D007328:Insulin / Q000097:blood; D008136:Longevity; D051379:Mice; D011374:Progesterone / Q000097:blood; D013974:Thyroxine / Q000097:blood
D006728:Hormones; D007328:Insulin; D011374:Progesterone; D004958:Estradiol; D013974:Thyroxine; D003345:Corticosterone