Cytotoxic effect of fatty acids in vitro on Ehrlich exudative carcinoma cells and normal exudative cells (leukocytes).
A mixture of pure fatty acids isolated hydrolytically from linseed oil in the form of water-soluble salts with ethanolamine were examined for cytotoxicity for Ehrlich carcinoma and normal exudative cells. Cytotoxicity of the mixture was similar to that of salts of oleic and linolenic acids. On the other hand, the mixture of fatty acids and oleic acids was more toxic for normal exudative cells than linolenic acid.
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy*; D005227:Fatty Acids / Q000627:therapeutic use*; D007962:Leukocytes / Q000187:drug effects*; D008042:Linolenic Acids / Q000627:therapeutic use; D008043:Linseed Oil; D051379:Mice
D005227:Fatty Acids; D008042:Linolenic Acids; D008043:Linseed Oil