Reaginic immune response to tree pollen antigen in LBN rats.
The immunogenicity and cross-antigenicity of ten common tree pollen allergens were studied in LBN rats. The rats produced IgE antibodies to each of the allergens used (maple, willow, poplar, ash, oak, sycamore, hickory, walnut, birch, and elm), yet the allergens had extremely limited cross-reactivity. The possible explanation for the limited cross-antigenicity is discussed.
D000818:Animals; D000917:Antibody Formation; D003429:Cross Reactions; D010323:Passive Cutaneous Anaphylaxis; D011058:Pollen; D051381:Rats; D011914:Rats, Inbred BN; D011935:Reagins / Q000096:biosynthesis*; D014197:Trees
D011935:Reagins