Cyclic peptides. II. Synthesis of AM-Toxin I.
To confirm the structure of AM-toxin I (a phytotoxic cyclotetradepsipeptide) the proposed peptide was prepared by a conventional method. The synthetic peptide and natural AM-toxin I were identical as regards t.l.c., u.v., mass spectra and biological activity in causing necrosis on apple leaves. A prepared dimer of AM-toxin I showed extremely weak activity; the relationship between the ring size and biological activity of AM-toxin I is discussed.
D013058:Mass Spectrometry; D008722:Methods; D010456:Peptides, Cyclic / Q000138:chemical synthesis*; D010944:Plants / Q000187:drug effects; D013056:Spectrophotometry, Ultraviolet; D014118:Toxins, Biological / Q000138:chemical synthesis*
D010456:Peptides, Cyclic; D014118:Toxins, Biological