Studies on exogenous and endogenous interaction of gastrin and secretin in a case of achalasia.
Studies were carried out in a case of achalasia. Administration of secretin caused relaxation of the spastic condition of LES, and high levels of serum gastrin and lower levels of plasma secretin are suggested to be related with the abnormally spastic condition of LES in the patient.
D000328:Adult; D004931:Esophageal Achalasia / Q000097:blood / Q000503:physiopathology*; D004947:Esophagus / Q000503:physiopathology*; D005755:Gastrins / Q000097:blood / Q000494:pharmacology* / Q000502:physiology; D006801:Humans; D008297:Male; D008722:Methods; D009119:Muscle Contraction / Q000187:drug effects*; D009126:Muscle Relaxation / Q000187:drug effects*; D011312:Pressure; D012633:Secretin / Q000097:blood / Q000494:pharmacology* / Q000502:physiology
D005755:Gastrins; D012633:Secretin