Directed biosynthesis of analogues of ergot peptide alkaloids with Claviceps purpurea.
Analogues of peptide ergot alkaloids can be obtained by feeding a producing culture of Claviceps purpurea with an analogue of one of the amino acids of the peptide chain of the alkaloid.
D000596:Amino Acids / Q000378:metabolism; D002967:Claviceps / Q000378:metabolism*; D004873:Ergolines / Q000031:analogs & derivatives / Q000096:biosynthesis; D004876:Ergot Alkaloids / Q000096:biosynthesis*
D000596:Amino Acids; D004873:Ergolines; D004876:Ergot Alkaloids