title: Thrombelastography during and after elective abdominal surgery.
abstract: Thrombelastography has been performed on recalcified whole blood from 50 patients before, during and after elective abdominal surgery. The characteristic changes of the thrombelastographic indices r, k and mA are described. During operation r and k shortened, but no change in mA was observed. This response was in part associated with an increase in factor VIII activity. Following operation, while r time was somewhat shortened, much more marked changes in k and mA were evident. Increasing fibrinogen concentration was the dominant factor in determining the post-operative changes in the thrombelastograph.
mesh_terms: D000005:Abdomen / Q000601:surgery*; D001772:Blood Cell Count; D001792:Blood Platelets; D005169:Factor VIII / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis*; D006801:Humans; D013916:Thrombelastography
chemical_list: D005169:Factor VIII; D005340:Fibrinogen