title: Levels of complement during interferon induction.
abstract: Further data were obtained in support of the finding that the levels of interferon and complement show a negative correlation after induction of interferon in vivo. Experiments with selective chelating agents showed that the activation of complement occurs by the by-pass mechanism. Preliminary results indicate that interferon itself can reduce the level of complement in vivo. Experiments are underway to verify in rats the results obtained in mice.
mesh_terms: D000818:Animals; D003165:Complement System Proteins / Q000032:analysis*; D007369:Interferon Inducers; D007372:Interferons / Q000096:biosynthesis* / Q000494:pharmacology; D051379:Mice; D009975:Orthomyxoviridae; D051381:Rats
chemical_list: D007369:Interferon Inducers; D003165:Complement System Proteins; D007372:Interferons