Primary meningeal mesenchymal chondrosarcoma.
A primary meningeal mesenchymal chondrosarcoma initially resembled an angioblastic meningioma because the typical chondroid islands were not demonstrable. Cartilage was seen only in an intracerebral recurrence and in subsequent extracranial metastases. Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material. Features of meningeal or pericytic cells were not seen.
D002648:Child; D002813:Chondrosarcoma / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D006394:Hemangiosarcoma / Q000175:diagnosis; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology*; D008578:Meninges / Q000473:pathology; D008637:Mesenchymoma / Q000473:pathology*; D009362:Neoplasm Metastasis