Vitamin C and gallstone formation: a preliminary report.
Gallstone formation in hypovitaminotic C guinea-pig fed a high cholesterol diet was associated with qualitative changes in the gallbladder bile, namely, a high cholesterol concentration, a lowered bile acid content and diminished phospholipid-to-cholesterol and bile acid-to-cholesterol ratio.
D000818:Animals; D001206:Ascorbic Acid Deficiency; D001646:Bile / Q000032:analysis; D001647:Bile Acids and Salts / Q000032:analysis; D002769:Cholelithiasis / Q000209:etiology*; D002784:Cholesterol / Q000032:analysis; D002791:Cholesterol, Dietary / Q000008:administration & dosage; D006168:Guinea Pigs; D010743:Phospholipids / Q000032:analysis
D001647:Bile Acids and Salts; D002791:Cholesterol, Dietary; D010743:Phospholipids; D002784:Cholesterol