Significance of anomalous thermoregulation in the pre-diabetic spiny mouse (Acomys cahirinus): cold tolerance: blood glucose and food consumption responses to environmental heat.
Decreased cold tolerance, reduced food requirement for body weight maintenance and comparative resistance to the hypoglycaemic effect of fasting in high ambient temperatures have been demonstrated in the spiny mouse. These phenomena could be related to anomalous spiny mouse thermoregulation, a phenomenon which is common in desert rodents and is simulated by mutant and artificially diabetic rodent species. The data can be interpreted as showing evidence for a survival advantage of genotypes with potential diabetic expression, and may provide an explanation of the geographic distribution of certain species.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D003080:Cold Temperature; D004435:Eating; D005215:Fasting; D005260:Female; D006358:Hot Temperature; D008297:Male; D051379:Mice; D011236:Prediabetic State / Q000097:blood / Q000503:physiopathology / Q000662:veterinary*; D012376:Rodent Diseases / Q000097:blood / Q000503:physiopathology*; D012377:Rodentia / Q000502:physiology
D001786:Blood Glucose