[Effect of hexenal and thiopental anesthesia on energy metabolism in different brain areas].
Respiration and oxidative phosphorylation were studied in dog mitochondria of visua and acoustic areas of brain cortex as well as of medial thalamus after hexenal and thiopental narcosis. The distinct increase in the respiratory activity, which was not accompanied by phosphate esterification, was observed in mitochondria of medial thalamus as compared with the organelles of brain cortex from visual and acoustic areas. The phenomenon was responsible for uncoupling of respiration and phosphorylation processes.
D000768:Anesthesia, General; D000818:Animals; D001303:Auditory Cortex / Q000187:drug effects / Q000378:metabolism; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D004285:Dogs; D006591:Hexobarbital / Q000494:pharmacology*; D010085:Oxidative Phosphorylation / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects; D013788:Thalamus / Q000187:drug effects / Q000378:metabolism; D013874:Thiopental / Q000494:pharmacology*; D014793:Visual Cortex / Q000187:drug effects / Q000378:metabolism
D006591:Hexobarbital; D013874:Thiopental
Vliianie geksenalovogo i tiopentalovogo narkoza na énergeticheskiĭ obmen v razlichnykh otdelakh golovnogo mozga.