title: [Disruption of the mechanisms of natural immunity in the initial stage of adjuvant disease in rats and guinea pigs].
abstract: Similar changes in the nonspecific immunity indices were noted in experiments on rats and guinea pigs with adjuvant disease: depression of blood serum bactericidal activity and increase of the lysozyme and complement level, as well as inhibition of the phagocytic activity of leukocytes and production of normal antibodies to O- and Vi-antigens of typhoid bacilli in rats. Changes in disturbances of natural immunity factors in adjuvant disease correlated with the severity of the process in both animal species.
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D001168:Arthritis / Q000276:immunology*; D001169:Arthritis, Experimental / Q000276:immunology*; D001770:Blood Bactericidal Activity; D003165:Complement System Proteins; D006168:Guinea Pigs; D007113:Immunity, Innate; D007962:Leukocytes / Q000276:immunology; D008297:Male; D009113:Muramidase / Q000097:blood; D010587:Phagocytosis; D051381:Rats; D012485:Salmonella typhi / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D003165:Complement System Proteins; D009113:Muramidase
vernacular_title: Narushenie mekhanizmov estestvennogo immuniteta v nachal'noĭ stadii ad'iuvantnoĭ belezni u krys i morskikh svinok.