Effects of analgesics during labor.
Four analgesic agents were studied during labour: pethidinesparine, ketamine hydrochloride, nitrous oxide-oxygen, and trichloroethylene in air (Trilene). Excellent analgesia was achieved with ketamine, however hallucinations were troublesome. Trichloroethylene analgesia was good without side-effects. Pethidine-sparine produced moderate analgesia but with nausea and/or vomiting. Nitrous oxide 50% presented poor analgesia. Uterine activity was insignificantly diminished in the late first stage after administration of all analgesic agents except with ketamine. There were no untoward effects on fetuses.
D000773:Anesthesia, Obstetrical; D005260:Female; D005318:Fetal Heart / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007649:Ketamine / Q000494:pharmacology*; D008614:Meperidine / Q000494:pharmacology*; D009609:Nitrous Oxide / Q000494:pharmacology*; D011247:Pregnancy; D014241:Trichloroethylene / Q000494:pharmacology*; D014590:Uterine Contraction / Q000187:drug effects*
D014241:Trichloroethylene; D007649:Ketamine; D008614:Meperidine; D009609:Nitrous Oxide