Two pericentric inversions of human chromosome 11.
A pericentric inv(11) (pl5q23) detectable by G-, Q-, and R-banding and occuring in 1 member of each of 3 generations of a family is described. In another family studied by several banding methods in search of chromosomal markers, a pericentric inv(11) (p11q11) was found. It was detectable only by C-banding, the darkly staining band being located on the short-arm side of the centromere. The reasons for defining this aberration as an inversion rather than a location variant are outlined. This inversion occurred in 9 members of 3 generations of a large family. There was no clear-cut evidence of any clinical consequences of these inversions either in heterozygotes or their offspring.
D001399:Azure Stains; D007446:Chromosome Inversion; D002875:Chromosomes / Q000648:ultrastructure; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D010375:Pedigree
D001399:Azure Stains