title: Clonogenic assays in the B16 melanoma: response to cyclophosphamide.
abstract: The survival of clonogenic cells in the B16 melanoma has been studied simultaneously by 3 methods: an in vitro assay in soft agar, a lung-colony assay, and the end-point dilution technique. Details of the first 2 methods have previously been reported, but those of the third are described here. The 3 methods have agreed well in investigations of the response of the B16 melanoma to cyclophosphamide.
mesh_terms: D002452:Cell Count; D002470:Cell Survival / Q000187:drug effects; D002999:Clone Cells / Q000187:drug effects; D003520:Cyclophosphamide / Q000494:pharmacology / Q000627:therapeutic use*; D066298:In Vitro Techniques; D008175:Lung Neoplasms; D008545:Melanoma / Q000188:drug therapy*; D009374:Neoplasms, Experimental / Q000188:drug therapy
chemical_list: D003520:Cyclophosphamide