title: Biological properties and clinical application of propolis. XI. Histophathological analysis after intravenous application of ethanol extract of poprolis (EEP).
abstract: Mice were given i.v. injections of water solutions of ethanol extract of propolis (EEP) over a varying period of time. Some of the animals were sacrificed immediately following the last injection and some within 2--4 weeks after the last injections. Internal organ samples were taken and underwent a microscopic examination. Insignificant pathological changes in the liver were observed. These changes were transient and regressed within 2--4 weeks after the application of EEP.
mesh_terms: D000818:Animals; D007668:Kidney / Q000473:pathology; D008099:Liver / Q000473:pathology; D008168:Lung / Q000473:pathology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009206:Myocardium / Q000473:pathology; D010537:Peritoneum / Q000473:pathology; D011429:Propolis / Q000633:toxicity*; D012116:Resins, Plant / Q000633:toxicity*; D013154:Spleen / Q000473:pathology; D013997:Time Factors
chemical_list: D012116:Resins, Plant; D011429:Propolis