[Effect of nociceptive stimulation on the mitotic activity of cutaneous epithelial cells surrounding a wound at different age periods].
Wounds, 1 cm in length, reaching the cutaneous muscle were inflicted to rats, aged 11 days, 2 and 2 1/2 months, under the right scapula. In 48 hours the animals were subjected to pain irritation with electric current. Mitotic activity was determined in the cells of the basal layer of cutaneous epithelium. Pain stimulation decreased the mitotic index of the cutaneous epithelium cells in animals of all the age groups under study considerably (several times). There was an increase of mitotic index from the early to later periods of postnatal ontogenesis.
D000367:Age Factors; D000818:Animals; D004848:Epithelium; D008297:Male; D008940:Mitotic Index; D010146:Pain; D051381:Rats; D012867:Skin / Q000293:injuries* / Q000473:pathology; D014945:Wound Healing
Vliianie notsitseptivnogo razdrazheniia na mitoticheskuiu aktivnost' kletok kozhnogo épiteliia, okruzhaiushchego ranu, v razlichnye vozrastnye periody.