[Studies on DNA content of tissues and organs. 2nd communication: findings on DNA content in various rat organs 1. during maturation and aging and 2. during experimental pathological models and their therapy (author's transl)].
In this paper the DNA content as a quantitative parameter of the cell content was analyzed on selected rat organs. Aging changes in parenchymatous and connective tissue (= mesenchymal) organs were examined. Further, some pilot studies on experimental animal models of human diseases (experimental shock and liver fibrosis) and their therapy were carried out. In these simulations of human diseases only some preliminary indications about changes in cell or DNA content, resp., of the various organs could be obtained. The results show that these pilot studies justify intensified continuation (in larger series).
D000375:Aging; D001011:Aorta / Q000378:metabolism; D003106:Colon / Q000378:metabolism; D004247:DNA / Q000378:metabolism*; D004195:Disease Models, Animal; D006128:Growth; D006801:Humans; D007421:Intestine, Small / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008106:Liver Cirrhosis, Experimental / Q000378:metabolism*; D008168:Lung / Q000378:metabolism; D010994:Pleura / Q000378:metabolism; D012769:Shock / Q000378:metabolism*; D012867:Skin / Q000378:metabolism
D004247:DNA
Untersuchungen zum DNS-Gehalt von Geweben und Organen. 2. Mitt.: Ergebnisse über den DNS-Gehalt verschiedener Organe der Ratte 1. während Reifung und Alterung und 2. während experimenteller Modelle menschlicher Erkrankungen und ihrer Behandlung.