Myopathy with multiple central cores. A case with hypersensitivity to pyrexia.
An eight-year-old male suffered from long-standing proximal muscle weakness, dramatically aggravated by febrile episodes. Neuromuscular work-up disclosed a myopathy with multiple central cores of non-familial nature. The presence of central cores in this patient as well as in the myopathy of malignant hyperpyrexia might suggest a pathophysiological basis common to both conditions.
D002648:Child; D005334:Fever / Q000150:complications*; D006801:Humans; D007223:Infant; D007866:Leg; D008297:Male; D009132:Muscles / Q000473:pathology*; D009135:Muscular Diseases / Q000150:complications / Q000151:congenital / Q000473:pathology*