[Gastroduodenostomy and duodenogastric reflux (author's transl)].
In 36 pigs the intragastric C14 bile acid reflux and the concentration of lysolecithin is measured following different types of hemigastrectomy and gastroduodenostomy. Termino-terminal, termino-lateral and supraduodenal termino-lateral anastomosisses were as well studied as an isoperistaltic jejunal transposition of 15 cm resp. 25 cm length.-After all types of direct gastroduodenostomy the amounts of intragastral C14 bile acids and lysolecithin were significantly elevated. An additional jejunal transposition decrease the reflux in relation to the length of the transposed jejunal segment. The importance of the duodenogastric reflex of bile acids and lysolecithin for the development of alkaline reflux gastritis and carcinoma of the gastric stump is discussed. For clinical purpose a replacement of the pyloric reflux barrier by a primary jejunal transposition in case of pylorectomy has to be discussed.
D000818:Animals; D001647:Bile Acids and Salts / Q000032:analysis; D004386:Duodenum / Q000601:surgery; D005743:Gastrectomy; D005756:Gastritis / Q000209:etiology; D005764:Gastroesophageal Reflux; D007583:Jejunum / Q000601:surgery; D008244:Lysophosphatidylcholines / Q000032:analysis; D010713:Phosphatidylcholines / Q000032:analysis; D013270:Stomach / Q000601:surgery; D013552:Swine
D001647:Bile Acids and Salts; D008244:Lysophosphatidylcholines; D010713:Phosphatidylcholines
Gastroduodenostomie und duodenogastraler Reflux. Eine tierexperimentelle Untersuchung.