Determination of red blood cell superoxide dismutase and glutathione peroxidase in newborns in relation to neonatal hemolysis.
Superoxide dismutase and glutathione peroxidase activities have been determined in newborns. Their mean values are approximately the same as in normal adults. In some cases a low content of superoxide dismutase and/or a high (superoxide dismutase/glutathione peroxidase) ratio are associated with hematological symptoms. In addition, a low superoxide dismutase activity is associated with hyperbilirubinemia and is present in two of the three cases showing maximal acetylphenylhdrazine-induced hemoloysis.
D000328:Adult; D004912:Erythrocytes / Q000201:enzymology*; D005979:Glutathione Peroxidase / Q000097:blood*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008722:Methods; D010544:Peroxidases / Q000097:blood*; D010659:Phenylhydrazines; D013482:Superoxide Dismutase / Q000097:blood*
D010659:Phenylhydrazines; D010544:Peroxidases; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase