Synthesis of some quinones of potential antitubercular activity.
Certain phthiocol derivatives of expected bactericidal action have been synthesized. These include the phthiocol moiety condensed with p-hydrazino-salicylic and -benzoic acids and their ethyl esters; phthiocol thiosemicarbazone and isonicotinyl hydrazidehydrazone. In another similar series the methyl group of phthiocol was replaced by carbethoxy, ethyl, butyl and isobutyl groups. Allyl and 1.2-epoxypropyl ethers of phthiocol being of high lipid dispersion were also synthesized.
D000995:Antitubercular Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D011809:Quinones / Q000138:chemical synthesis*; D013055:Spectrophotometry, Infrared / Q000379:methods
D000995:Antitubercular Agents; D011809:Quinones