title: [Analysis of 300 cases of secondary pancytopenia].
abstract: Clinical analysis of 300 cases of secondary pancytopenia treated in a period of 10 years is reported. The disease was more frequent in women than in men. The most frequent single cause were drugs, among them chloramphenicol. Most patients had pancytopenia and hypoplastic bone marrow. The mortality was 37%. Death occurred most frequently in the first 6 months of the disease due to infection or thrombocytopenic heamorrhagic diathesis. The results of treatment with corticosteroids and androgenic steroids were unsatisfactory.
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000728:Androgens / Q000627:therapeutic use; D002701:Chloramphenicol / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010198:Pancytopenia / Q000139:chemically induced / Q000188:drug therapy; D012737:Sex Factors
chemical_list: D000305:Adrenal Cortex Hormones; D000728:Androgens; D002701:Chloramphenicol
vernacular_title: Analiza 300 przypadków pancytopenii wtórnych.