Circadian variation in an amphetamine induced motor response.
Significant diurnal variation in occurrence and duration of D-amphetamine induced head-shaking were observed in 9-day-old rats. The lowest values were obtained near noon, and the highest around midnight. These variations should be considered if head-shaking is to be used as a quantitative neuropharmacological test.
D000818:Animals; D002940:Circadian Rhythm; D003913:Dextroamphetamine / Q000494:pharmacology*; D009043:Motor Activity / Q000187:drug effects* / Q000502:physiology; D051381:Rats
D003913:Dextroamphetamine