Vesico-ureteral reflux and uninhibited neurogenic bladder.
Ureteral reflux in female patients who also have latent uninhibited neurogenic bladder occurs synchronously with uninhibited contraction, is blocked by buscopan and is aggravated by besacholine. Intrinsic neuromuscular antireflux mechanism of the vesicoureteral junction (VUJ) appears to be affected by unknown ways with uninhibited contraction. Urethrovesical reflux observed synchronously with uninhibited contraction seems to play an additional role in the genesis of urinary infection. A different look is required in the management of these refluxes, in that concomitant use of the anticholinergic drugs is recommended in addition to the conventional approach for the control of infection, reflux and voiding symptoms.
D002648:Child; D005260:Female; D006801:Humans; D008875:Middle Aged; D010276:Parasympatholytics / Q000627:therapeutic use; D010277:Parasympathomimetics / Q000009:adverse effects; D014513:Ureter / Q000294:innervation; D001750:Urinary Bladder, Neurogenic / Q000150:complications*; D014718:Vesico-Ureteral Reflux / Q000150:complications* / Q000188:drug therapy
D010276:Parasympatholytics; D010277:Parasympathomimetics