title: [Oxidative phase of pentose-phosphate cycle in sea mussel (mytilus edulis l.) (author's transl)].
abstract: Glucose-6-phosphate dehydrogenase (E.C. 1.1.1.49) and 6-phosphogluconate dehydrogenase (E.C. 1.1.1.44) activities measured in tissue extracts from sea mussel exhibit a potential unbalance which could cause an accumulation of 6-phosphogluconate. Nevertheless elevated levels of this metabolite are not detected in mussel tissues. The Entner-Doudoroff pathway has not been found in hepatopancreas, adductor muscle and gill tissues. Hepatopancreas glucose-6-phosphate-dehydrogenase and 6-phosphogluconate dehydrogenase apparent kinetic parameters at 25 degrees C, were determined. The enzymes are competitively inhibited by NADPH with respect to NADP+. Oxidized Glutathione at nearly physiological concentrations counteracts NADPH inhibition.
mesh_terms: D049872:Bivalvia / Q000201:enzymology*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism*; D010084:Oxidation-Reduction; D010734:Phosphogluconate Dehydrogenase / Q000378:metabolism*
chemical_list: D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase
vernacular_title: Fase oxidativa de la ruta de las pentosas en diversos tejidos de mejillón, Mytilus edulis l.