Granulomatous hepatitis in a healthy adult following BCG injection into a plantar wart.
This is the first reported case of granulomatous hepatitis in a healthy adult following intralesional injection of BCG into a plantar wart. Previous reports of disseminated disease following intralesional injections have all been in patients with malignancies. The clinical course in this patient was characterized by fever, chills and drainage from the injection site. Diagnosis was made by demonstration of noncaseating granulomas on liver biopsy. No acid-fast organisms were identified by stain or culture. The patient responded to antituberculous therapy.
D000328:Adult; D001500:BCG Vaccine / Q000009:adverse effects* / Q000627:therapeutic use; D001707:Biopsy, Needle; D005260:Female; D005528:Foot; D006099:Granuloma / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006505:Hepatitis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D014860:Warts / Q000628:therapy*
D001500:BCG Vaccine