Regression of atheroma in the rabbit.
Ten studies in the literature concerning regression of rabbit atheroma were re-examined. In studies where cholesterol content was referred to weight, a degree of regression was noted in 3/4 studies. Such regression might at least partly have resulted from the dilution effect of the atheroma contents when results were expressed on a weight basis. By contrast, when results were referred to length or protein, partial regression was seen in only 1/4 studies. Mild atheroma induced by short-term cholesterol feeding did seem to regress in 2/2 studies.
D000818:Animals; D001011:Aorta / Q000032:analysis / Q000473:pathology*; D001161:Arteriosclerosis / Q000378:metabolism / Q000473:pathology*; D001835:Body Weight; D002784:Cholesterol / Q000032:analysis; D002791:Cholesterol, Dietary; D004195:Disease Models, Animal; D005069:Evaluation Studies as Topic; D005260:Female; D008297:Male; D011817:Rabbits
D002791:Cholesterol, Dietary; D002784:Cholesterol