Amyloidosis. An unusual complication of Gaucher's disease.
Gaucher's disease has been associated with plasma cell dyscrasias. A patient had Gaucher's disease, nephrotic syndrome, and systemic amyloidosis. Plasmacytosis in the bone marrow, the presence of light chains in the urine and renal glomeruli, and the finding of low circulating immunoglobulin levels suggest that the amyloid in this patient is related to a plasma cell dyscrasia.
D000686:Amyloidosis / Q000150:complications* / Q000473:pathology; D005260:Female; D005776:Gaucher Disease / Q000150:complications* / Q000235:genetics; D006801:Humans; D007674:Kidney Diseases / Q000150:complications / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010265:Paraproteinemias / Q000150:complications*; D013158:Splenic Diseases / Q000209:etiology / Q000473:pathology