title: The incidence of urolithiasis in peptic ulcer patients.
abstract: Two hundred patients suffering from peptic ulcer have been examined for urinary stones. Two hundred healthy controls have been similary studied. In 14 patients from the first group (7%) urinary calculi were found, whereas the percentage in the second group was only 1%. This difference is statistically significant (P less than 0.01) (x2 distribution test). The increased incidence of peptic ulcer was attributed to the consumption of calcium in combination with easily absorbable alkalis (sodium bicarbonate). These findings must be considered in therapy for peptic ulcer diathesis.
mesh_terms: D000137:Acid-Base Imbalance / Q000150:complications; D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001639:Bicarbonates / Q000009:adverse effects / Q000627:therapeutic use; D002118:Calcium / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008892:Milk / Q000009:adverse effects; D010437:Peptic Ulcer / Q000150:complications* / Q000188:drug therapy; D014545:Urinary Calculi / Q000453:epidemiology / Q000209:etiology*
chemical_list: D001639:Bicarbonates; D002118:Calcium