[On an improved device for measuring skin tearing strength. Technical description and experimental results obtained from rat skin following therapy with topical corticoids (author's transl)].
Technical details of an improved method for measuring tensile behaviour of normal and treated rat skin are described. The apparatus has been developed specifically for skin specimens so that the extending force and the adequate strain rate until rupture are designed especially for this purpose. Skin is to be mounted in the jaws of the instrument in horizontal position. Preliminary biological data have been worked out.
D000287:Administration, Topical; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D005448:Fluocortolone / Q000031:analogs & derivatives / Q000494:pharmacology*; D006854:Hydrocortisone; D008297:Male; D010827:Physiology / Q000295:instrumentation; D011244:Pregnadienediols / Q000494:pharmacology*; D051381:Rats; D012867:Skin / Q000187:drug effects; D012879:Skin Physiological Phenomena; D013718:Tensile Strength / Q000187:drug effects
D000893:Anti-Inflammatory Agents; D011244:Pregnadienediols; D005448:Fluocortolone; D006854:Hydrocortisone
Uber ein verbessertes Zugprüfgerät für den Hautreissversuch. Beschreibung der Technik und Versuchsergebnisse an Hautproben der Ratte nach Behandlung mit topisch wirksamen Corticoiden.