Ultrastructure of hyaline microthrombi in myocardial capillaries of pigs with spontaneous "mulverry heart disease".
Three 5-week-old pigs from an Indiana farm died of the cardiac form ("mulberry heart disease") of selenium-vitamin E deficiency. Grossly, the hearts had prominent hydropericardium and extensive serosal and myocardial hemorrhage. Histopathologic study demonstrated marked myocardial edema, congestion, and hemorrhage, with numerous capillary hyaline microthrombi that stained red with the periodic-acid Schiff rocedure. Ultrastructural study revealed that these thrombi were composed of elongated, dense masses of intertwined fibrin strands with occasional entrapped erythrocytes.
D000818:Animals; D002196:Capillaries / Q000648:ultrastructure*; D003327:Coronary Disease / Q000473:pathology / Q000662:veterinary*; D006331:Heart Diseases / Q000473:pathology / Q000662:veterinary*; D009206:Myocardium / Q000648:ultrastructure*; D012643:Selenium / Q000172:deficiency*; D013552:Swine; D013553:Swine Diseases / Q000473:pathology*; D014811:Vitamin E Deficiency / Q000662:veterinary*
D012643:Selenium