Impedance rheoplethysmography. The role of estimation of vasodilatory activity.
The activity of a number of vasodilatory drugs was studied, with the help of impedance rheoplethysmography, on the vascular bed of the hind limb of anaesthetized rabbits. The vasodilators under study induce changes in rheoplethysmogram to a more or less important degree. The results were compared with those obtained with electromagnetic flowmetry. This method seems to be useful in the study of vasodilators because it allows to measure their effects and the duration thereof in a non-aggressive way. This method using flowmetry, allows to study in an analytical way those substances' effects on artery, vein and also capillary.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004078:Dihydralazine / Q000494:pharmacology; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D008297:Male; D009599:Nitroprusside / Q000494:pharmacology; D010891:Piribedil / Q000494:pharmacology; D010992:Plethysmography, Impedance; D011817:Rabbits; D013997:Time Factors; D014664:Vasodilation / Q000187:drug effects*
D009599:Nitroprusside; D010891:Piribedil; D004078:Dihydralazine