title: [The effect of tramadol, a new analgesic, on respiration and cardiovascular function (author's transl)].
abstract: 1. The effect of 1-(m-methoxyphenyl)-2-(dimethylaminomethyl)-cyclohexan-1-ol (tramadol; Tramal), a new i.v. administered analgesic, on respiration and cardiovascular function was investigated in 15 patients in a clinic of general surgery. 2. Blood gas analysis revealed that tramadol, unlike morphine-like analgesics, does not depress respiration. 3. The drug did not affect blood pressure, and the observed slight increase in heart rate was transient and statistically not significant.
mesh_terms: D000700:Analgesics / Q000494:pharmacology*; D001784:Blood Gas Analysis; D003511:Cyclohexanols / Q000494:pharmacology*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D012119:Respiration / Q000187:drug effects*; D013997:Time Factors
chemical_list: D000700:Analgesics; D003511:Cyclohexanols
vernacular_title: Uber die Wirkung von Tramadol auf Atmung und Kreislauf.