Circannual variation in human erythrocyte adenosine aminohydrolase.
In serially independent samples of blood from apparently healthy subjects controlled as to clock-hour of blood withdrawal but not as to any circannual changes in circadian state, human erythrocyte adenosine aminohydrolase undergoes a statistically significant circannual rhythm, which may or may not be aliased. This rhythm is also demonstrated in patients with a variety of neoplastic diseases and it occurs around a statistically significantly lower mesor in patients with a variety of malignant tumors investigated.
D000243:Adenosine Deaminase / Q000097:blood*; D004912:Erythrocytes / Q000201:enzymology*; D006801:Humans; D009369:Neoplasms / Q000201:enzymology; D009700:Nucleoside Deaminases / Q000097:blood*; D012621:Seasons
D009700:Nucleoside Deaminases; D000243:Adenosine Deaminase