Transtympanic electrocochleography in patients with syphilis and hearing loss.
Transtympanic electrocochleography was carried out on 18 syphilitic patients (30 ears were tested) most of whom were suffering from the late onset congenital form of the disease. A diphasic action potential with a large negative summating potential on the descending limb was found in 77.7% of ears; the cochlear microphonic potential was always of small amplitude. While these findings are not pathognomonic of syphilis, they are characteristic and may be explained on pathological grounds.
D000200:Action Potentials; D000293:Adolescent; D000328:Adult; D000368:Aged; D003051:Cochlea / Q000473:pathology / Q000503:physiopathology*; D004594:Electrophysiology; D005260:Female; D006311:Hearing Disorders / Q000503:physiopathology*; D006801:Humans; D007762:Labyrinthitis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013587:Syphilis / Q000473:pathology / Q000503:physiopathology*; D013590:Syphilis, Congenital / Q000473:pathology