Pulmonary nocardiosis in a patient receiving immunosuppressive agent.
A 20-year-old woman receiving corticosteroid treatment for systemic lupus erythematosus developed pulmonary nocardiosis with hydrophneumothorax. The organism identified as Nocardia asteroides resisted to sulfonamide and cotrimoxazole but sensitive to chloramphenicaol and streptomycin in vitro. She seemed to respond to chloramphenicol but subsequently had peritonitis and succumbed later.
D000328:Adult; D002701:Chloramphenicol / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy; D009617:Nocardia Infections / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D013449:Sulfonamides / Q000627:therapeutic use
D013449:Sulfonamides; D002701:Chloramphenicol; D011239:Prednisolone