Comparative study of two anti-ulcerogenic drugs--glaziovine and sulpiride.
The anti-ulcer effect of glaziovine, a major psychotropic alkaloid isolated from Ocotea glaziovii (Laureaceae) and belonging to a new chemical class, has been studied in different types of experimentally induced ulcers in the guinea-pig and the rat. The effect of glaziovine was compared with that of sulpiride.
D000818:Animals; D000897:Anti-Ulcer Agents; D001060:Aporphines / Q000494:pharmacology*; D005260:Female; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology; D008297:Male; D011708:Pylorus / Q000502:physiology; D051381:Rats; D012110:Reserpine / Q000494:pharmacology; D012149:Restraint, Physical; D012701:Serotonin / Q000494:pharmacology; D013276:Stomach Ulcer / Q000139:chemically induced / Q000503:physiopathology; D013469:Sulpiride / Q000494:pharmacology*
D000897:Anti-Ulcer Agents; D001060:Aporphines; D012701:Serotonin; D013469:Sulpiride; D006632:Histamine; D012110:Reserpine