[Effect of fluocortin butylester (0.75%) as an ointment in the pyrexal erythema test on human skin (author's transl)].
The antiinflammatory efficacy of butyl 6alpha-fluoro-11beta-hydroxy-16alpha-methyl-3,20-dioxo-1,4-pregnadien-21-oate (fluocortin butylester, Vaspit) as a 0,75% ointment was tested in comparison with 1% hydrocortisone acetate ointment in the model of the pyrexal erythema. Fluocortin butylester appeared to be significantly superior to hydrocortisone acetate.
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D004890:Erythema / Q000188:drug therapy*; D005448:Fluocortolone / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use*; D006801:Humans; D006854:Hydrocortisone; D009824:Ointments; D011244:Pregnadienediols / Q000627:therapeutic use*
D000893:Anti-Inflammatory Agents; D009824:Ointments; D011244:Pregnadienediols; D005448:Fluocortolone; D006854:Hydrocortisone
Wirksamkeit von Fluocortin-butylester (0.75%) als Salbe im Pyrexalerythem-Test an der menschlichen Haut.