[Effect of phentolamine on the electroencephalogram and pulse activity of the cortical neurons].
In tests with vigilant immobilized and also urethan anesthetized rabbits the influence of intravenous injection of phentolamine (3--10 mg/kg) on the EEG waves parameters was studied. It is shown that within 45 to 75 minutes following introduction of phentolamine there is observed either shortening or elimination of the EEG activation reaction in response to stimulation of the sciatic nerve. The blocking effect of the intravenous administration of phentolamine is noted also by following dynamic changes in the discharge activity of single neurons.
D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects* / Q000502:physiology; D003344:Cortical Synchronization; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D004569:Electroencephalography; D004594:Electrophysiology; D005071:Evoked Potentials / Q000187:drug effects; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D010646:Phentolamine / Q000494:pharmacology*; D011817:Rabbits
D010646:Phentolamine
Vliianie fentolamina na élektroéntsefalogrammu i impul'snuiu aktivnost' korkovykh neĭronov.