An in vivo preparation (Thiry-Vella fistula) suitable for the measurement of intestinal absorption in the guinea pig.
A thiry-Vella isolated intestinal loop was constructed in the guinea pig. The procedure consisted of removal of a 30-cm segment of the jejunem, restoration of intestinal continuity by a jejunojejunostomy, and exteriorization of the segment through stomata sutured to the skin. The procedure was performed on seven guinea pigs of which three survived. The three survivors remained normal in maintenance of hair, feeding, and weight gain over a long period.
D000818:Animals; D006168:Guinea Pigs / Q000378:metabolism / Q000601:surgery*; D007408:Intestinal Absorption; D007412:Intestinal Fistula; D007583:Jejunum / Q000378:metabolism / Q000601:surgery*; D008297:Male; D008722:Methods