title: [Clinical experience with S-6436 in urinary tract infections (author's transl)].
abstract: S-6436 is a new preparation of sustained release cephalexin. Twenty-eight patients with urinary tract infections were orally given 500mg of S-6436 twice a day for about 7 days, and the following results were obtained: 1) Excellent clinical responses were observed in 8 cases, good in 18 cases and failure in 2 cases. Effectiveness was 93%. 2) As for the side effect, gastrointestinal symptoms were observed in one case out of 28 cases, but they disappeared after the completion of the treatment. No other side effects due to S-6436 were observed. S-6436 has as much effectiveness and safety as compared with usual cephalexin preparations. The frequency of the administration of S-6436 is twice a day, which means that S-6436 is more convenient in giving it to patients than usual cephalexin preparations.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002506:Cephalexin / Q000008:administration & dosage*; D002908:Chronic Disease; D003692:Delayed-Action Preparations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008875:Middle Aged; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D003692:Delayed-Action Preparations; D002506:Cephalexin