Lipid droplet of sebaceous carcinoma. Electron microscopic study utilizing glycol methacrylate-glutaraldehyde-urea procedure.
The ultrastructure of lipid droplets of sebaceous carcinoma (Meibomian gland carcinoma) was studied by conventional methods and a lipid-retention procedure. Two different structures were clearly differentiated by the latter technique. The peripheral part of the lipid droplet was composed of whirled lamellar structures (myelin-like structures) while the interior appeared to be continuously homogenous. The lamellar structures were presumed to have come from smooth-surfaced endoplasmic reticulum, and to transform to the amorphous material-triglyceride-during maturation of the lipid droplets. A true limiting membrane or membranous shell around the lipid droplet was not deceted.
D000368:Aged; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D005142:Eyelid Neoplasms / Q000032:analysis / Q000473:pathology; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008055:Lipids / Q000032:analysis*; D008853:Microscopy; D008854:Microscopy, Electron; D012626:Sebaceous Gland Neoplasms / Q000032:analysis* / Q000473:pathology; D014280:Triglycerides / Q000032:analysis
D008055:Lipids; D014280:Triglycerides