[The radioimmunological assay of fibrinogen breakdown products with E antigen during postoperative venous thromboses. Study in 46 cases of arthroplasty for osteoarthrosis of the hip (author's transl)].
Twenty six patients (without thrombosis) had a normal 125I-fibrinogen test, among whom 15 had a normal phlebography; 18 patients (with thrombosis) had a positive 125I-fibrinogen test among whom 11 had a positive phlebography. There was a discrepancy between phlebography and 125I-fibrinogen test in 2 patients. In patients with thrombosis, there is a significantly increase of FgE levels for several days after the intervention. However the measurement of FgE is not a reliable test (4% of false positive and 38% of false negative); but it is always elevated in femoral and popliteal thrombosis.
D000328:Adult; D000368:Aged; D000941:Antigens / Q000032:analysis*; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis* / Q000276:immunology; D005340:Fibrinogen / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000097:blood*; D011863:Radioimmunoassay; D013924:Thrombophlebitis / Q000097:blood* / Q000209:etiology / Q000276:immunology
D000941:Antigens; D005338:Fibrin Fibrinogen Degradation Products; D005340:Fibrinogen
Le dosage radioimmunologique des produits de dégradation du fibrinogène possédant l'antigène E, au cours des thromboses veineuses post-opératoires. Etude à l'occasion de 46 arthroplasties pour coxarthrose.