title: Responses to sustained use of anabolic steroid.
abstract: Description is given of six body-builders who had been taking Methandrostenolone (up to 20 mg/day in intermittent courses for a year or more). At the time of examination there was no subjective disturbance of sexual function, but testosterone levels were low relative to laboratory standards and luteinizing hormone levels were also reduced - particularly in relation to testosterone concentrations. Abnormal liver function tests were seen in three of the six subjects, and one had mild diabetes with high serum cholesterol, triglycerides and uric acid. The weight gain of the group was not outstanding, and the only possible finding was a high haemoglobin and haematocrit in one of the six subjects.
mesh_terms: D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D002784:Cholesterol / Q000097:blood; D003920:Diabetes Mellitus / Q000139:chemically induced; D004300:Doping in Sports; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008111:Liver Function Tests; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008696:Methandrostenolone / Q000008:administration & dosage / Q000494:pharmacology*; D008875:Middle Aged; D013739:Testosterone / Q000097:blood; D014280:Triglycerides / Q000097:blood; D014527:Uric Acid / Q000097:blood
chemical_list: D006454:Hemoglobins; D014280:Triglycerides; D014527:Uric Acid; D013739:Testosterone; D007986:Luteinizing Hormone; D002784:Cholesterol; D008696:Methandrostenolone; D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase