Cicloxilic acid and the bile lipids in oral contraceptive users.
Cholesterol supersaturation of gallbladder bile induced by oral contraceptives is significantly reduced by the administration of cis-2-hydroxy-2-phenyl-cyclohexane-carboxilic acid (cicloxilic acid), a choleretic substance which has been demonstrated to exert an antilithogenic effect in the rat and in man.
D000293:Adolescent; D000328:Adult; D001646:Bile / Q000187:drug effects* / Q000378:metabolism; D002756:Cholagogues and Choleretics / Q000494:pharmacology*; D002784:Cholesterol / Q000378:metabolism; D003276:Contraceptives, Oral / Q000037:antagonists & inhibitors*; D003278:Contraceptives, Oral, Hormonal / Q000037:antagonists & inhibitors*; D003509:Cyclohexanecarboxylic Acids / Q000494:pharmacology*; D005260:Female; D006801:Humans; D050356:Lipid Metabolism
D002756:Cholagogues and Choleretics; D003276:Contraceptives, Oral; D003278:Contraceptives, Oral, Hormonal; D003509:Cyclohexanecarboxylic Acids; D002784:Cholesterol