title: Implications of the 99mTc diphosphonate bone scan on treatment of primary breast cancer.
abstract: The 99mTc diphosphonate scan is important in the study of primary breast cancer. The short-term prognosis for scan-positive patients is poor. Serial bone scans provide a safe and reliable prognostic index in patients following mastectomy. By correlating the scan with biochemical tumor markers, a matrix of diagnostic tests may be developed that is capable of identifying high-risk patients who may benefit from systemic therapy.
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging*; D001943:Breast Neoplasms / Q000628:therapy*; D004164:Diphosphonates; D005260:Female; D006801:Humans; D008408:Mastectomy; D009362:Neoplasm Metastasis; D011182:Postoperative Care; D011379:Prognosis; D011877:Radionuclide Imaging; D012306:Risk; D013667:Technetium
chemical_list: D004164:Diphosphonates; D013667:Technetium