Inflammatory giant cells: immunophagocytosis and rosette formation.
Mouse inflammatory giant cells formed after subcutaneous implantation of coverslips were exposed to sheep red blood cells opsonized with isologous antibodies. The maximal number of engulfed erythrocytes in numerous multinuclear cells exceeded that encountered in subcutaneous macrophages, but, on a per nucleus basis, the giant cells appeared less phagocytic.
D000818:Animals; D007249:Inflammation / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D051379:Mice; D008811:Mice, Inbred DBA; D010587:Phagocytosis; D012397:Rosette Formation