title: Small spherical viruses in faeces from gastroenteritis patients.
abstract: Faecal samples from 238 patients with gastroenteritis were examined by direct electron microscopy using grids with thin carbon film. Of these samples 18 were found to contain Norwalk agent-like particles, calicivirus, astrovirus and parvovirus-like particles. Immune electron microscopy was performed on a serum pair and faeces from one of the patients with astrovirus. An antibody response was demonstrated, suggesting that the virus was the etiological agent of the infection.
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D005243:Feces / Q000382:microbiology*; D005759:Gastroenteritis / Q000382:microbiology*; D006801:Humans; D010321:Parvoviridae / Q000276:immunology / Q000302:isolation & purification / Q000648:ultrastructure; D014780:Viruses / Q000276:immunology / Q000302:isolation & purification / Q000648:ultrastructure
chemical_list: D000914:Antibodies, Viral