title: [Blood level values of rectally applied theophylline and its derivative proxyphylline and diprophylline in aqueous enema (author's transl)].
abstract: Serum levels of theophylline and two of its oxypropylic derivatives were determined in repetitive blood samples after instillation of a mixture of the three substances by means of an aqueous enema. From the time course of serum levels a rapid onset of bronchodilation and rather a long-lasting bronchodilatory effect of about 8 h may be expected. Side effects are rare. The pharmacological characteristics of the three compounds are discussed.
mesh_terms: D001993:Bronchodilator Agents; D004733:Enema; D006801:Humans; D013806:Theophylline / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000097:blood* / Q000494:pharmacology; D013997:Time Factors
chemical_list: D001993:Bronchodilator Agents; D013806:Theophylline
vernacular_title: Blutspiegelwerte von rektal verabreichtem Theophyllin und seiner Derivate Proxyphyllin und Diprophyllin im wässerigen Clysma.