title: Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of the central effects of scopolamine (Hyoscine).
abstract: Galanthamine hydrobromide, an anticholinesterase drug capable of penetrating the blood-brain barrier, was used in a patient demonstrating central effects of scopolamine (hyoscine) overdosage. It is longer acting than physostigmine and is used in anaesthesia to reverse the non-depolarizing neuromuscular block. However, studies into the dose necessary to combating scopolamine intoxication are indicated.
mesh_terms: D000328:Adult; D002490:Central Nervous System / Q000187:drug effects*; D003128:Coma / Q000139:chemically induced / Q000188:drug therapy*; D003692:Delayed-Action Preparations / Q000009:adverse effects; D005702:Galantamine / Q000494:pharmacology / Q000627:therapeutic use*; D006212:Hallucinations / Q000139:chemically induced / Q000188:drug therapy*; D006801:Humans; D008297:Male; D012601:Scopolamine / Q000009:adverse effects / Q000506:poisoning*; D013405:Suicide
chemical_list: D003692:Delayed-Action Preparations; D005702:Galantamine; D012601:Scopolamine