title: Effects of two analgesic opiates (methadone and pentazocine) on the serum prolactin levels in breast cancer.
abstract: In 18 female patients affected by advanced breast cancer, the serum prolactin (PRL) levels have been determined under basal conditions and after the administration of analgesic opiates such as methadone and pentazocine. A significant increase of prolactin serum values was found after the use of both drugs. This finding is considered to be of clinical importance.
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000097:blood / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008691:Methadone / Q000627:therapeutic use*; D008875:Middle Aged; D010423:Pentazocine / Q000627:therapeutic use*; D011388:Prolactin / Q000097:blood*
chemical_list: D011388:Prolactin; D010423:Pentazocine; D008691:Methadone