Evaluation of Tc-99m pyridoxal-phenylalanine as a hepatobiliary agent. Part 2. Clinical tests.
Twenty-four patients with normal or diseased hepatobiliary systems were subjected to a clinical trial in order to evaluate Tc-99m pyridoxal-phenylalanine as a biliary imaging agent. The investigation was combined with i.v. cholecysto-cholangiography in most cases, and the results were compared. It is concluded that qualitative information derived from conventional i.v. cholangiography is better in demonstrating the normal biliary tree or gallstones. The radiotracer techniques, however, are valuable in dynamic studies of Oddi's sphincter, in showing patency of biliary by-pass procedures, and in differentiating hepatocellular from obstructive jaundice.
D000368:Aged; D001659:Biliary Tract / Q000000981:diagnostic imaging*; D001660:Biliary Tract Diseases / Q000000981:diagnostic imaging; D002758:Cholangiography; D002765:Cholecystography; D002769:Cholelithiasis / Q000000981:diagnostic imaging; D002779:Cholestasis / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging*; D008107:Liver Diseases / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010649:Phenylalanine; D011730:Pyridoxal; D011877:Radionuclide Imaging; D009803:Sphincter of Oddi / Q000000981:diagnostic imaging; D013667:Technetium
D011730:Pyridoxal; D010649:Phenylalanine; D013667:Technetium