Prospective analysis of antiribonucleoprotein antibodies in systemic lupus erythematosus.
A prospective analysis of 50 successive patients with systemic lupus erythematosus, seen over a 4-year period, has been completed. 336 sera were examined for the presence of antibody to ribonucleoprotein using a counterimmunoelectrophoresis assay. Antibody was present in the sera of 16% of patients and was detectable in about the same titre throughout the course of the disease. The presence of the antibody did not appear to identify a subgroup of lupus patients with individual clinical characteristics.
D000906:Antibodies / Q000032:analysis*; D003165:Complement System Proteins / Q000032:analysis; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D009698:Nucleoproteins / Q000276:immunology*; D011446:Prospective Studies; D012261:Ribonucleoproteins / Q000276:immunology*
D000906:Antibodies; D009698:Nucleoproteins; D012261:Ribonucleoproteins; D003165:Complement System Proteins