Kinetics and mechanism of degradation of some 2-sulfanilamidopyrimidine derivatives. Part V. Mechanism of sulfadimidine solvolysis.
The products of spontaneous hydrolysis of sulfadimidine are: sulfanilamide, aniline, 2-hydroxy- 4,6-dimethylpyrimid and ammonium carbonate. The mechanism of spontaneous hydrolysis of sulfadimidine is proposed.
D000814:Aniline Compounds / Q000032:analysis; D002850:Chromatography, Gel; D004355:Drug Stability; D006868:Hydrolysis; D007700:Kinetics; D011743:Pyrimidines / Q000032:analysis; D000644:Quaternary Ammonium Compounds / Q000032:analysis; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013418:Sulfamethazine / Q000032:analysis; D013424:Sulfanilamides / Q000032:analysis
D000814:Aniline Compounds; D011743:Pyrimidines; D000644:Quaternary Ammonium Compounds; D013424:Sulfanilamides; D013418:Sulfamethazine