[Studies of the blood pool dynamic actions of dipyridamole in pregnancy (author's transl)].
The action of 2,6-bis(diethanolamino)-4,8-dipiperidinopyrimido-(5,4-d)pyrimidine (dipyridamole, Persantin) on utero-placental and cardiac blood pool dynamics was examined in 12 pregnant women. 113mIndium was injected i.v. and blood pool changes in the heart, placenta and myometrium were registered by external measurement of the gamma-activity. While there was a significant decrease in blood pool of the heart after dipyridamole, there were no marked changes in the blood pools of placenta or myometrium. The decrease in cardiac blood pool was interpreted as a sign of an increase in the cardiac output.
D000328:Adult; D003326:Coronary Circulation / Q000187:drug effects; D004176:Dipyridamole / Q000494:pharmacology*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D010920:Placenta / Q000098:blood supply; D011247:Pregnancy / Q000187:drug effects*; D012039:Regional Blood Flow / Q000187:drug effects; D014599:Uterus / Q000098:blood supply
D004176:Dipyridamole
Untersuchungen über blutpooldynamische Wirkungen von Dipyridamol in der Schwangerschaft.