[2-(Diethylamino)pyrimidines 2nd Communication: Analgesics (author's transl)].
By condensation of 1,1-diethylguanidine (1) with beta-diketones (2), the 2-(diethylamino)pyrimidines (3) are formed. Aside from beta-diketones substituted by aliphatic (2 a--e), mixed aliphatic-aromatic (2f), and pure aromatic-carbocyclic (2g and h) moieties, also those carrying aromatic-heterocyclic (2i and 4) substitutents are amenable to this reaction.
D000700:Analgesics / Q000138:chemical synthesis*; D000818:Animals; D000935:Antifungal Agents / Q000138:chemical synthesis; D055598:Chemical Phenomena; D002621:Chemistry; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D011743:Pyrimidines / Q000032:analysis / Q000138:chemical synthesis* / Q000494:pharmacology; D011930:Reaction Time / Q000187:drug effects; D013055:Spectrophotometry, Infrared
D000700:Analgesics; D000935:Antifungal Agents; D011743:Pyrimidines
2-(Diäthylamino)pyrimidine. 4. Mitteilung: Analgetika.