[Methods for detecting "cataleptic states" in the rat].
For the detection of drug-induced cataleptic states four new methods of "dynamic" character are described. They are based on passive extension of the muscles, changes in spatial position or force to motoric activity. Together with the well-known methods of "static" character, they are compiled to a "Test Battery" in which eight neuroleptics as well as bulbocapnine, metoclopramide, two cholinergic and two opioid drugs were investigated. Due to the pattern of reaction in the "Test Battery" it is possible to differentiate between various classes of cataleptiogenic drugs.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D002375:Catalepsy / Q000139:chemically induced* / Q000503:physiopathology; D006220:Haloperidol / Q000494:pharmacology; D006801:Humans; D008722:Methods; D010095:Oxotremorine / Q000494:pharmacology; D051381:Rats
D010095:Oxotremorine; D006220:Haloperidol
Methodisches Vorgehen zur Erfassung "kataleptischer Zustände" bei der Ratte.