Filter columns for preparation of leukocyte-poor blood for transfusion.
Filter columns (Imugard filters) packed with cotton wool prepared from Gossypium barbadense cotton removed 95--100% of leukocytes from packed red cell suspensions. Recovery of red cells was about 95%. The efficacy was similar for ACD and heparinized blood. Blood was filtered below 10 degrees C within 30 min under pressures of less than 0.2 kg/cm2. The shape and functions of the red cells were not altered by filtration. No pyrogenic or toxic substances, and little particulate matter were eluted from the filters.
D000818:Animals; D005374:Filtration / Q000295:instrumentation / Q000379:methods; D003368:Gossypium; D010956:Plasmapheresis; D014935:Wool