Cytogenetic study of 10 cases of infectious mononucleosis.
Cytogenetic analysis of 10 cases of infectious mononucleosis has revealed increased damage in the form of chromosome breakage and aberrations typical of viral infection, but in addition a few cells were consistently found to harbour a deleted number 22, similar tsponse to the mitogen phytohaemagglutinin is suggested. This inhibitor appears to have a reversible action on the patient's own lymphocytes but no inhibitory effect on control lymphocytes.
D000293:Adolescent; D000328:Adult; D002869:Chromosome Aberrations; D002872:Chromosome Deletion; D002904:Chromosomes, Human, 21-22 and Y; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007244:Infectious Mononucleosis / Q000097:blood / Q000235:genetics*; D008213:Lymphocyte Activation; D008297:Male