title: Neural pathway mediating somatic evoked responses in the caudate nucleus of cats.
abstract: The course of somatic afferents to caudate nucleus (CN) was investigated. In curaized cats discrete lesions in intralaminar nuclei, n. centralis medialis (NCM) affect evoked response (ER) in CN to radial nerve stimulation. NCM lesions totally abolish these somatic responses, while after subthalamic lesions ER appear only when a high stimulus intensity is used. Lesions in the specific relay nuclei, ventralis posterior lateralis (VPL) have no effect on somatic ER in CN. Barbiturates (10 mg/kg) abolish somatic ER in CN. Stimulation of the ponto-mesencephalic reticular formation (RF) in a region where visual and somatic responses are recorded shows lowest threshold values for eliciting evoked responses in NCM and CN. The potentials in CN to RF stimulation are restricted to this nucleus and disappear in the internal capsule.
mesh_terms: D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D001463:Barbiturates / Q000494:pharmacology; D001933:Brain Stem / Q000502:physiology*; D002415:Cats; D002421:Caudate Nucleus / Q000187:drug effects / Q000502:physiology*; D005071:Evoked Potentials; D005260:Female; D008297:Male; D008636:Mesencephalon / Q000502:physiology; D011930:Reaction Time; D012154:Reticular Formation / Q000502:physiology; D013787:Thalamic Nuclei / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology
chemical_list: D001463:Barbiturates