title: Influence of fasting period, ligation time, sex, age and bodyweight on the gastric secretory response of pylorus-ligated Wistar rats.
abstract: A study on variables influencing the gastric secretory response of pylorus-ligated Wistar rat, shows that: 1. 24 h is a sufficient fasting period for satisfactory emptying of the stomach, periods of up to 48 h yielding no advantage; 2. between 2 and 4 h is the most appropriate pyloric ligation time because in this range there are no variations in volume of gastric secretion, concentration and output of acid per unit of ligation time; 3. sex has no influence on any of the parameters; 4. animals should be age-selected because only above a given age threshold the gastric secretory response per unit of bodyweight is constant.
mesh_terms: D000375:Aging; D000818:Animals; D001835:Body Weight; D005215:Fasting; D005260:Female; D005750:Gastric Juice / Q000378:metabolism*; D008026:Ligation; D008297:Male; D011708:Pylorus / Q000502:physiology; D051381:Rats; D012737:Sex Factors; D013997:Time Factors