title: Onset of illness in bipolar manic-depressives and their affectively ill first-degree relatives.
abstract: Some suggestive data regarding age of onset and the relationship of stress to onset in a group of bipolar manic-depressive patients and their first-degree relatives are presented. Possible explanations of the interesting correlation in age of onset among family members are discussed. Because of a small sample size, the clinical significance of the findings are uncertain, but are presented because of their potential interest to those investigating genetic components of affective illness.
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001714:Bipolar Disorder / Q000235:genetics*; D003863:Depression / Q000235:genetics; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013315:Stress, Psychological