title: [Experience from a 3-year administration of megestrol acetate of karakul sheep].
abstract: Five milligram of megestrol acetate were orally used over ten days during mating periods to synchronise oestrus in caracool sheep. Eighteen days were allowed to elapse from the last administration of progestagen before 1,000 I.U. PMSG were injected to boost fertility. The test reported in this paper had been applied to a large sheep herd over three years. The following conclusions were drawn: Synchronised occurrence of heat in the mating period was not reduced by oral administration of 5 mg megestrol acetate over ten days for a period of three years (87.1 to 95.5 per cent). The fertilisation rate in response to first insemination was between 68.8 and 73.1 per cent. Birth to lambs was given by 85-92 per cent of the ewes after two inseminations. No fertility occurred in 1.5-3.1 per cent of all animals.
mesh_terms: D000818:Animals; D004341:Drug Evaluation; D004973:Estrus Synchronization / Q000187:drug effects; D005260:Female; D005298:Fertility / Q000187:drug effects; D007315:Insemination, Artificial / Q000662:veterinary; D008297:Male; D008535:Megestrol / Q000008:administration & dosage*; D011247:Pregnancy; D012756:Sheep / Q000502:physiology*; D013997:Time Factors
chemical_list: D008535:Megestrol
vernacular_title: Opyt trekhletnego primeneniia megestrola na karakul'skikh ovtsakh.