[Anaplastic carcinoma of the thyroid gland with chondroid, osteoid, and marocellular metaplasia of the stroma, associated with Hashimoto's lymphocytic thyroiditis].
Anaplastic, mostly spindle-cellular, carcinoma of the thyroid gland was diagnosed bioptically in a 65-year-old woman. Necroptically it was found that the carcinoma was associated with Hashimoto's lymphocytic thyroiditis. In the hitherto-differentiated carcinomatous parts the papillary component prevailed and the original lymphocytic stromal infiltration was in evidence here. In the anaplastic parts isolated macrocellular elements occurred and, in some places, also chondroid and osteoid structures, especially the structures of macrocellular bone tumor character. These structures were entirely missing in the distant metastases and were, therefore, evaluated as a stromal nontumorous metaplastic process.
D000368:Aged; D002277:Carcinoma / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008679:Metaplasia; D013961:Thyroid Gland / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000150:complications* / Q000473:pathology; D013967:Thyroiditis, Autoimmune / Q000150:complications*
Anaplastický karcinom stítné zlázy s chondroidní, osteoidní a obrovskobunĕcnou metaplazií stromatu, sdruzený s Hashimotovou lymfocytární (thyreoiditídou).