Efficacy of seven anthelmintics against Ancylostoma ceylanicum in the golden hamster, Mesocricetus auratus.
In an experimental patent infection of Ancylostoma ceylanicum in golden hamsters the efficacy of seven anthelmintics was tested; bephenium hydroxynaphthoate, tetramisole, tetrachlorethylene, phenylene 1,4-diisothiocyanate, thiabendazole, parbendazole and mebendazole were studied. Mebendazole was the most effective, with parbendazole, phenylene 1,4-diisothiocyanate, thiabendazole and bephenium hydroxynaphthoate also satisfactory. Tetrachlorethylene and tetramisole were the least effective in our screen.
D000724:Ancylostomiasis / Q000188:drug therapy*; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use; D001598:Bephenium Compounds / Q000627:therapeutic use; D006224:Cricetinae; D007422:Intestines / Q000469:parasitology; D008463:Mebendazole / Q000627:therapeutic use; D008647:Mesocricetus; D013827:Thiabendazole / Q000627:therapeutic use
D000871:Anthelmintics; D001562:Benzimidazoles; D001598:Bephenium Compounds; D008463:Mebendazole; D013827:Thiabendazole