Dynamics of anti-vaccinia HAI antibodies during the first month after smallpox revaccination at 20 years.
Anti-vaccina HAI antibody titers were dynamically followed up and correlated with the type of cutaneous reaction in 91 small pox revaccines aged 20-21 years. Serum samples collected at 2-day intervals for 14 days and on day 30 post inoculation (p.i.) were tested. Antibody titer rises began on days 4-6 and continued until day 14 p.i. On day 30 further rises were only recorded in the 9 vaccinees with primovaccinal reactions. The rhythm of antibody rises was almost the same in subjects with ambiguous and major cutaneous reactions.
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D000917:Antibody Formation; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007117:Immunization, Secondary; D012882:Skin Tests; D012899:Smallpox / Q000517:prevention & control*; D012900:Smallpox Vaccine; D013997:Time Factors
D000914:Antibodies, Viral; D012900:Smallpox Vaccine