[Practical and theoretical aspects of genetic family counselling in mucoviscidosis (author's transl)].
It is now obvious that mucoviscidosis possesses an autosomatic recessive heredity. It is not yet clear whether the cause will be found in only one or in several mutant genes. A definite assertion on the genetics of mucoviscidosis can not be done until a practicable test for heterozygotes is available allowing representative investigations. As long as this is not so a repeat risk of at least 25% should be taken as a basis for adequately counselling parents of patients with mucoviscidosis.
D003550:Cystic Fibrosis / Q000235:genetics / Q000517:prevention & control*; D005260:Female; D005808:Genes, Recessive; D005817:Genetic Counseling; D005838:Genotype; D006579:Heterozygote; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D013997:Time Factors
Praktische und theoretische Aspekte der genetischen Familienberatung bei Mukoviszidose.