Possible high dosage gentamycin therapy in infected neutropenic patients.
Serum gentamycin levels have been studied in 23 neutropenic infected patients after high doses (62 mg/m2 and 72 mg/m2) of the drug, we observed: a higher gentamicin level than with an usual dosage, levels under the ototoxic 10/ml level, no renal failure, and, no patient ototoxicity.
D000380:Agranulocytosis / Q000150:complications*; D000667:Ampicillin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005839:Gentamicins / Q000008:administration & dosage* / Q000097:blood / Q000627:therapeutic use; D006801:Humans; D007239:Infections / Q000150:complications / Q000188:drug therapy*; D009503:Neutropenia / Q000150:complications*
D005839:Gentamicins; D000667:Ampicillin