Indirect atomic absorption analysis of ethambutol.
In the presence of cupric ions and sodium hydroxide, ethambutol forms a chelate compound which can be extracted with ethyl-methyl ketone. The amount of ethambutol-copper complex was determined by measuring the copper by Atomic Absorption Spectroscopy (AAS) in the ethylmethyl ketone extract. When this method was applied to pharmaceutical samples satisfactory results were obtained. The method is accurate for routine analyses and very simple to be carried out.
D055598:Chemical Phenomena; D002621:Chemistry; D004977:Ethambutol / Q000032:analysis*; D008722:Methods; D013054:Spectrophotometry, Atomic
D004977:Ethambutol