[Modeling experimental pollinosis].
Experimental pollinosis was modelled on guinea pigs. The animals were placed in a cell in which an allergen-water-dialyzed extract of ambrosia pollen was dispersed by means of coaxial pulveriser. Homocytotropic antibodies serving as indices of animal sensitization to the specific allergen formed in guinea pigs as a result of aerosol sensitization. Sensitization of the animals to the ambrosia allergen was accompanied by an increase of sensitivity of the broncho-pulmonary apparatus and was characterized by the bronchospastic reaction in resolving inhalation or inrtavenous injection of a specific allergen.
D000336:Aerosols; D000485:Allergens; D000818:Animals; D002457:Cell Extracts; D004195:Disease Models, Animal; D006168:Guinea Pigs; D010323:Passive Cutaneous Anaphylaxis; D011058:Pollen; D012119:Respiration; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology / Q000503:physiopathology
D000336:Aerosols; D000485:Allergens; D002457:Cell Extracts
Modelirovanie éksperimental'nogo pollinoza.