Stability of rat skin collagen during recovery from under-nutrition.
The growth of young rats was arrested for 6 weeks from 48 h after receiving an injection of L-[5-3H]proline. The 3H in the hydroxyproline of the newly synthesized skin collagen remained steady during under-nutrition and did not decrease during the subsequent recovery period. It was concluded that in this animal model the renewed growth did not induce degradation of the pre-existing collagen fibres.
D000818:Animals; D003094:Collagen / Q000378:metabolism*; D006128:Growth; D006909:Hydroxyproline / Q000378:metabolism; D008297:Male; D009748:Nutrition Disorders / Q000378:metabolism*; D051381:Rats; D012867:Skin / Q000378:metabolism
D003094:Collagen; D006909:Hydroxyproline