[Effect of oxygen and hypergravitation on alveolar surfactant].
The effect of prolonged exposure (up to 66 hours) to pure oxygen breathing and to short (5-minute) oxygen breathing combined with acceleration (+5Gz) on the surface tension and surface potential of the alveolar washout of the albino rat lungs was determined. Both experimental conditions produced atelectasis and a decrease of the surfactant surface activity. Possible mechanisms of shifts of the surfactant activity under hyperoxia only, and hyperoxia with accelerations are discussed.
D000818:Animals; D004594:Electrophysiology; D006112:Gravitation; D008168:Lung / Q000032:analysis* / Q000502:physiology; D008297:Male; D010100:Oxygen; D011663:Pulmonary Surfactants / Q000032:analysis*; D051381:Rats; D013500:Surface Tension
D011663:Pulmonary Surfactants; D010100:Oxygen
Vliianie kisloroda i gipergravitatsii na al'veoliarnyĭ surfaktant.