A possible role for gut GLI: an inhibitor of lipolysis.
Duck gut GLI was incubated a) alone and b) with the lipolytically active duck pancreatic GLI and the intestinal factors peak 2 and 3, and the glycerol released from duck adipocytes measured. Intestinal GLI was non-lipolytic, but not inert: it reduced the lipolysis induced by pancreatic GLI and peak 2.
D000273:Adipose Tissue / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D005768:Gastrointestinal Hormones / Q000494:pharmacology*; D005934:Glucagon / Q000494:pharmacology*; D005990:Glycerol / Q000378:metabolism; D066298:In Vitro Techniques; D008053:Lipid Mobilization / Q000187:drug effects*; D010187:Pancreatic Hormones / Q000494:pharmacology
D005768:Gastrointestinal Hormones; D010187:Pancreatic Hormones; D005934:Glucagon; D005990:Glycerol