[Formation and release of antibodies in lymphocytes].
An immunohistochemical study proved that lymphocytes were the dominant cell type responsible for the production of antibodies during the local humoral immune response to human serum albumin in the mouse omentum. Ultrastructurally, specific antibodies were detected on ribosomes and polysomes linked to the perinuclear cisterna and placed in it, as well as on the free intracytoplasmic ribosomes and polysomes. In no case antibodies were found in other cell organelles involved in protein synthesis. Most probably the mechanismus of antibody release from lymphocytes are different from similar processes taking place in plasma cells.
D000818:Animals; D000906:Antibodies / Q000032:analysis*; D000917:Antibody Formation; D000918:Antibody Specificity; D005260:Female; D008214:Lymphocytes / Q000276:immunology*; D051379:Mice; D009852:Omentum / Q000276:immunology; D012270:Ribosomes / Q000276:immunology; D012756:Sheep
D000906:Antibodies
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