Systemic amyloidosis and hypogammaglobulinemia.
Small deposits of amyloid were found at autopsy in the kidneys, liver, spleen, and blood vessels of the intestines of a patient known to have primary acquired hypogammaglobulinemia. Previously described cases of hypogammaglobulinemia-associated amyloid are reviewed and possible pathogenetic mechanisms are discussed. The pathogenesis of amyloidosis in this patient is not known.
D000293:Adolescent; D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications* / Q000276:immunology; D000368:Aged; D000686:Amyloidosis / Q000150:complications*; D001987:Bronchiectasis / Q000150:complications; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008875:Middle Aged
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M