[Gestonoroncapronate and carbohydrate metabolism during radiotherapie of female patients suffering from cancer of the genitals (author's transl)].
Glucose tolerance test (oral standard glucose tolerance test) was carried out--before starting radiotherapy--in 99 female patients suffering from inoperable cancer of the genitals. 47 of these patients were administered gestonoroncapronate (600 mg/week) during radiotherapy. Glucose tolerance was tested anew after the last irradiation. During the first hour after the second glucose tolerance test, an improvement of glucose tolerance was stated in the patients' group treated with gestonoroncapronate, whereas during the second hour a deterioration of glucose tolerance was found. The patients' collective treated without gestonoroncapronate demonstrated an improved glucose tolerance during the entire second course of the test. A decrease of capacity of the islet cell organ, induced by gestonoroncapronate, is discussed.
D050260:Carbohydrate Metabolism; D005260:Female; D005833:Genital Neoplasms, Female / Q000188:drug therapy / Q000378:metabolism* / Q000532:radiotherapy; D005866:Gestonorone Caproate / Q000378:metabolism* / Q000627:therapeutic use; D005951:Glucose Tolerance Test; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy
D005866:Gestonorone Caproate
Gestonoroncapronat und Kohlenhydratstoffwechsel bei der Bestrahlung weiblicher Genitalkarzinome.