title: [Clinical aspects of a change in the nervous system after 49-day head-down hypokinesis].
abstract: Clinical and neurological methods were used to investigate the state of the central nervous system of 9 healthy male test subjects during a 49-day head-down (at an angle of 4-6 degrees) bed rest experiment. Beginning with the 4-5th week polymorphic changes in the nervous state emerged and developed. They can be divided into three clinical syndromes: astheno-neurotic syndrome that of autonomic dysfunction and the syndrome of neuromuscular (trophic) and statokinetic disorders. In comparison with the clinostatic bed rest, head-down tilting brought about changes in the nervous system earlier and with a more distinct "acute" phase. This is in favour of the concept that hemodynamic changes in the brain and the upper body play a very important part in the pathogenetic mechanism that underlies most disorders accompanying bed rest.
mesh_terms: D000222:Adaptation, Physiological; D000328:Adult; D001510:Bed Rest; D001794:Blood Pressure; D001833:Body Temperature Regulation; D006801:Humans; D009129:Muscle Tonus; D009132:Muscles / Q000503:physiopathology; D009420:Nervous System / Q000503:physiopathology*; D011187:Posture; D011674:Pulse; D013997:Time Factors
vernacular_title: Klinicheskie aspekty izmeneniia nervnoĭ sistemy pri 49-sutochnoĭ antiortostaticheskoĭ gipokinezii.