[A previously unpublished indication for sulpiride: functional uterine hemorrhages].
Sulpiridin has been shown to be remarkably efficient in treating functional uterine haemorrhage (70 per cent success). It is especially so in the pre-menopause. Its mode of action takes place on three levels: the hypothalamus, where it works on the clonic centre for the release of gonadotrophins (the tonic centre not being affected); the ovaries, where it lessens the sensitivity of the reaction of the ovary to gonadotrophins; the uterus, where there is direct action on the thickness of the mucous lining of the uterus and on its blood supply.
D000328:Adult; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007031:Hypothalamus / Q000187:drug effects; D008593:Menopause; D008595:Menorrhagia / Q000188:drug therapy*; D008796:Metrorrhagia / Q000188:drug therapy*; D008875:Middle Aged; D010053:Ovary / Q000187:drug effects; D013469:Sulpiride / Q000009:adverse effects / Q000627:therapeutic use*; D014599:Uterus / Q000187:drug effects
D013469:Sulpiride
Une indication inédite du sulpiride: les hémorragies utérines fonctionnelles.