title: Problems of model testing.
abstract: At first, a model is defined generally and a classification into descriptive and mechanistic models is made. A definition of what is meant by testing the adequacy of regression type models is given. The situations with or without repeated measurements are distinguished. The principle of the decision theoretical approach for model discrimination is compared with that of the significance test for adequacy. Finally, the problem of the optimality of experimental designs with respect to tests of adequacy is discussed. The arguments are demonstrated with various examples.
mesh_terms: D000367:Age Factors; D000818:Animals; D006801:Humans; D008954:Models, Biological; D010919:Placebos; D012107:Research Design; D013223:Statistics as Topic
chemical_list: D010919:Placebos