Data concerning the action of specific antiherpes immunoglobulins on the evolution of some nasopharyngeal and larynegeal neoplasms.
The administration of specific antiherpes immunoglobulins (Ig) to 9 patients with nasopharyngeal and laryngeal neoplasms resulted in the regression of metastatic lymph nodes, the absence of other metastatic localizations and the survival--in a good general state--of all the patients treated, for 23-29 months. Most of the patients received no other treatment during this time interval. In a control group consisting of 11 patients with the same forms of cancer, but who received no Ig, 4 fatal outcomes were recorded and all patients required re-hospitalization and application of other treatments. The method suggested may represent an efficient adjuvant therapy in some nasopharyngeal and laryngeal neoplasms.
D000328:Adult; D000368:Aged; D006564:Herpesviridae / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000627:therapeutic use*; D007167:Immunotherapy; D007822:Laryngeal Neoplasms / Q000276:immunology / Q000628:therapy*; D008207:Lymphatic Metastasis / Q000628:therapy; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000276:immunology / Q000628:therapy*
D007136:Immunoglobulins