Calmette-Guerin bacillus treatment of experimental conjunctival malignant melanoma.
Malignant melanoma of the conjunctival region was induced in the golden Syrian hamster. Inoculation of this lesion with Calmette-Guerin bacillus (BCG), 48 hours after injection of 10(3) tumor cells, either slowed, limited, or completely prevented the growth of the tumor in 56% of the treated eyes. In 98% of the control eyes, malignant melanoma grew rapidly and extensively.
D000818:Animals; D001500:BCG Vaccine / Q000627:therapeutic use*; D003228:Conjunctiva; D006224:Cricetinae; D005134:Eye Neoplasms / Q000276:immunology / Q000473:pathology / Q000628:therapy*; D005260:Female; D007167:Immunotherapy; D008545:Melanoma / Q000276:immunology / Q000473:pathology / Q000628:therapy*; D008647:Mesocricetus; D009374:Neoplasms, Experimental / Q000276:immunology / Q000473:pathology / Q000628:therapy
D001500:BCG Vaccine