Effect of tranexamic acid on choroidal melanoma.
Four cases of malignant choroidal melanoma have been treated with the antifibrinolytic agent tranexamic acid (Cyklocapron). One patient treated for six months showed no progression in tumor growth. Three eyes have been enucleated, and the histological examination revealed that the tumours were surrounded by fibrin. No side-effects of the treatment were observed.
D000328:Adult; D000368:Aged; D002829:Choroid / Q000473:pathology; D002830:Choroid Neoplasms / Q000188:drug therapy* / Q000473:pathology; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D014148:Tranexamic Acid / Q000627:therapeutic use*; D058609:Visual Field Tests
D003509:Cyclohexanecarboxylic Acids; D014148:Tranexamic Acid