title: Placental coccidioidomycosis without fetal disease.
abstract: We encountered two cases of maternal coccidioidomycosis with placental involvement. Altered cell-mediated immunity during pregnancy makes the diagnosis of desseminated coccidioidomycosis difficult by the routine serologic tests; placental examination provides specific information. A high index of suspicion regarding this disease and prompt institution of appropriate therapy are necessary in order to decrease maternal and neonatal mortality.
mesh_terms: D000328:Adult; D003047:Coccidioidomycosis / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D005315:Fetal Diseases; D006801:Humans; D010922:Placenta Diseases / Q000175:diagnosis / Q000473:pathology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000473:pathology*