Studies of respiratory function in volunteers given live influenza virus vaccine.
Measurements of peak flow, vital capacity, FEV1 and flow volume studies were performed in healthy volunteers for 20 weeks following intranasal vaccination with live-attenuated A/Victoria/3/75 recombinants or placebo. Despite differing attenuation of the two candidate strains, no effect on pulmonary function was detected.
D000328:Adult; D000914:Antibodies, Viral; D005260:Female; D005540:Forced Expiratory Flow Rates; D005541:Forced Expiratory Volume; D006801:Humans; D009980:Influenza A virus / Q000276:immunology / Q000302:isolation & purification; D007252:Influenza Vaccines / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012119:Respiration; D014613:Vaccines, Attenuated / Q000009:adverse effects*; D014797:Vital Capacity
D000914:Antibodies, Viral; D007252:Influenza Vaccines; D014613:Vaccines, Attenuated