title: Determination of red blood cell superoxide dismutase and glutathione peroxidase in newborns in relation to neonatal hemolysis.
abstract: Superoxide dismutase and glutathione peroxidase activities have been determined in newborns. Their mean values are approximately the same as in normal adults. In some cases a low content of superoxide dismutase and/or a high (superoxide dismutase/glutathione peroxidase) ratio are associated with hematological symptoms. In addition, a low superoxide dismutase activity is associated with hyperbilirubinemia and is present in two of the three cases showing maximal acetylphenylhdrazine-induced hemoloysis.
mesh_terms: D000328:Adult; D004912:Erythrocytes / Q000201:enzymology*; D005979:Glutathione Peroxidase / Q000097:blood*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008722:Methods; D010544:Peroxidases / Q000097:blood*; D010659:Phenylhydrazines; D013482:Superoxide Dismutase / Q000097:blood*
chemical_list: D010659:Phenylhydrazines; D010544:Peroxidases; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase