[Effect of caffeine on the frequency of radiation-induced chromosome aberrations at different stages of the cell cycle].
The effect of caffeine on the frequency of chromosome aberrations in human lymphocytes irradiated at different stages of the cell cycle was studied. Caffeine appeared to nearly double the frequency of chromosome aberrations induced by irradiation at S and G2 stages and did not influence the effect of irradiation at G0 and G1 stages.
D002110:Caffeine / Q000494:pharmacology*; D002453:Cell Cycle / Q000187:drug effects / Q000528:radiation effects*; D002478:Cells, Cultured; D002842:Chromatids / Q000187:drug effects / Q000528:radiation effects; D002869:Chromosome Aberrations; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects / Q000528:radiation effects; D013997:Time Factors
D002110:Caffeine
Vliianie kofeina na chastotu aberratsiĭ khromosom, indutsirovannykh radiatsieĭ v razlichnykh stadiiakh kletochnogo tsikla.