[On the metabolism of antipyrine (phenazone) in man (author's transl)].
The metabolism of antipyrine (phenazone) was studied by means of C14-antipyrine labelled at C-3. Besides the metabolites already known two conjugates were isolated and characterized by their mass spectra. The occurrence of 2-hydroxymethyl-3-methyl-1-phenyl-3-pyrazolin-5-one and 3,4-dihydroxy-2,3-dimethyl-1-phenyl-pyrazolidin-5-one could not be confirmed, although 95% of the radioactivity administered was recovered.
D000983:Antipyrine / Q000378:metabolism*; D001711:Biotransformation; D005965:Glucuronates / Q000378:metabolism; D006801:Humans; D006900:Hydroxylation; D013057:Spectrum Analysis
D005965:Glucuronates; D000983:Antipyrine
Zum Metabolismus von Antipyrin (Phenazon) beim Menschen.