In vivo effect of cyclic nucleotides on velocity and chemotaxis of neutrophil granulocytes.
Neutrophil granulocytes velocity and chemotaxis were obeserved by a direct method. Only chemotaxis could be inhibited by dibutyryl Cyclic AMP, this phenomenon could be reversed by cyclic GMP.
D000818:Animals; D002465:Cell Movement / Q000187:drug effects; D002634:Chemotaxis, Leukocyte / Q000187:drug effects; D006098:Granulocytes; D007962:Leukocytes / Q000187:drug effects; D009504:Neutrophils; D009712:Nucleotides, Cyclic / Q000494:pharmacology*; D051381:Rats
D009712:Nucleotides, Cyclic