Lysosomes in Brenner's tumor simulating secretory argentaffin granules.
Argentaffin cells were searched for in the epithelial nests of 30 Brenner's tumors, with the Fontana-Masson stain for the screening. Although these cells were found in five tumors, ultrastructural examination of one case, in which the argentaffin cells were multiple, identified the cytoplasmic granules as lysosomes and not as amine precursor uptake and decarboxylation (APUD)-type granules. We conclude that the epithelial component of Brenner's tumors consists of urothelium only and does not include the cells containing argentaffin APUD-type granules.
D001948:Brenner Tumor / Q000473:pathology* / Q000648:ultrastructure; D002838:Chromaffin System / Q000473:pathology*; D004759:Enterochromaffin Cells / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008247:Lysosomes / Q000473:pathology / Q000648:ultrastructure; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000648:ultrastructure