[Free cation protein secreted by gastric epithelium as an ingredient of the alkaline component of gastric juice].
The results of the study suggest that the secrete of the gastric lining epithelium of man and dog contains a free cation protein which is a macromolecular ingredient of the alkaline component of gastric juice. Under conditions of increasing and persisting hypersecretion of the acid, first the surface and then the pit epithelium increasingly secrete cation protein, and in the gastric juice an increased content of the alkaline component is detected. Subsequently, with persisting hypersecretion, the synthesizing capacity of the epithelial cells is exhausted and this is accompanied by a deficiency of the alkaline component in gastric juice.
D000328:Adult; D000818:Animals; D002412:Cations; D004285:Dogs; D004381:Duodenal Ulcer / Q000473:pathology / Q000503:physiopathology; D005745:Gastric Acidity Determination; D005750:Gastric Juice / Q000032:analysis*; D005753:Gastric Mucosa / Q000378:metabolism* / Q000473:pathology; D005756:Gastritis / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D011506:Proteins / Q000032:analysis / Q000378:metabolism*
D002412:Cations; D011506:Proteins
Svobodnyĭ kationnyĭ belok, sekretiruemyĭ pokrovnym epiteliem zheludka, kak sostnavaia chast' shchelochnogo komponenta.