title: A peptide containing aspartic acid, glutamic acid and serine in calf brain synaptic vesicles.
abstract: Free amino acids and other amino compounds in calf brain synaptic vesicles were identified and determined by thin-layer chromatography and ion-exchange chromatography. The vesicles contained ten identified amino acids with glutamic acid, aspartic acid, taurine and gamma-aminobutyric acid in the highest concentrations, and also cysteic acid (or cysteinesulfinic acid), glutamine, alanine, serine, glycine and lysine. The vesicles also contained certain unknown acid-labile, ninhydrin-positive compounds, one of which was a peptide yielding, after acid hydrolysis, about 40% aspartic acid, 30% serine, 15% glutamic acid, 10% glycine and possibly some alanine and lysine. The concentration of the peptide in the vesicles was as high as that of all the other amino compounds together.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001224:Aspartic Acid / Q000032:analysis*; D001923:Brain Chemistry; D002417:Cattle; D002852:Chromatography, Ion Exchange; D002855:Chromatography, Thin Layer; D005971:Glutamates / Q000032:analysis*; D010455:Peptides / Q000032:analysis*; D012694:Serine / Q000032:analysis*; D013572:Synaptic Vesicles / Q000032:analysis*
chemical_list: D000596:Amino Acids; D005971:Glutamates; D010455:Peptides; D001224:Aspartic Acid; D012694:Serine