title: [Histopathological diagnosis in the animal experiment (author's transl)].
abstract: Spontaneous and experimentally induced organ alterations in laboratory animals do not always coincide with comparable lesions in human pathology. In addition, the discrimination between experimental tissue alterations and non-pathological structural variations may be difficult. In such cases a clear-cut separation can only be achieved by a proven dose-response relation, which, however, requires a quantitative or semiquantitative registration of histological findings.
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D009374:Neoplasms, Experimental / Q000473:pathology; D010336:Pathology / Q000379:methods*; D051381:Rats; D013045:Species Specificity
vernacular_title: Die histopathologische Diagnostik im Tierversuch.