[The influence of an overdose of vitamin A on the rat fetal membranes in the last third of the pregnancy (author's transl)].
The ultrastructure of the rat fetal membranes (yolk-sac) was examined following an intrauterine overdose of vitamin A (Retinol palmitate). Three and six hours after the injection drastic lesions of the yolk-sac surface cells were to be seen, obviously mainly due to the numerous leaky lysosomes present in the yolk-sac epithelium.
D000818:Animals; D005260:Female; D010873:Pinocytosis / Q000187:drug effects; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014801:Vitamin A / Q000008:administration & dosage / Q000494:pharmacology*; D015017:Yolk Sac / Q000187:drug effects* / Q000502:physiology / Q000648:ultrastructure
D014801:Vitamin A
Die Wirkung einer Uberdosis Vitamin A auf die Eihaut der Ratte im letzten Graviditätsdrittel.