title: Treatment of obsessive-compulsive neurosis with clomipramine (Anafranil).
abstract: An uncontrolled clinical study was carried out to evaluate the therapeutic efficacy of clomipramine (Anafranil, Geigy Pharmacueticals) in a group of twenty obsessive-compulsive neurotic patients. Clomipramine proved to be extremely useful in alleviating obsessive-compulsive neurosis as well as phobia. This finding was not secondary to the improvement in anxiety or depression which occurred, as the degree of improvement in obsessive symptoms far exceeded the improvement in the other symptoms.
mesh_terms: D000328:Adult; D000368:Aged; D001007:Anxiety / Q000523:psychology; D002997:Clomipramine / Q000009:adverse effects / Q000627:therapeutic use*; D003863:Depression / Q000523:psychology; D003984:Dibenzazepines / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009770:Obsessive Behavior / Q000523:psychology; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy* / Q000523:psychology; D010698:Phobic Disorders / Q000523:psychology
chemical_list: D003984:Dibenzazepines; D002997:Clomipramine