Contribution to the early diagnosis of congenital toxoplasmosis.
A method based on a single serological test enabling the diagnosis of congenital toxoplasmosis immediately after birth is described. The concentration of anti-toxoplasmosis antibody from the CSF is compared to that of rubeola used as reference. It is thus possible to distinguish between the passive passage of antibodies in the CSF and their in situ synthesis. When concentration of antibody in the CSF is higher for toxoplasmosis than for rubeola, the existence of a congenital infection of toxoplasmosis can be suggested.
D000906:Antibodies / Q000032:analysis* / Q000134:cerebrospinal fluid; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008457:Measles / Q000276:immunology; D012698:Serologic Tests; D014125:Toxoplasmosis, Congenital / Q000175:diagnosis* / Q000276:immunology
D000906:Antibodies