Myocardial ultrastructural changes in Kugelberg-Welander syndrome.
Electron microscopical study of a biopsied specimen of myocardium from a patient with the Kugelberg-Welander syndrome revealed myocardial degeneration, including preferential loss of myosin filaments and abnormalities in the Z bands. Leptomeric fibrils were also observed in the cardiac muscle cell; there does not appear to be a previous report of the finding of such fibrils in human myocardium.
D000328:Adult; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009133:Muscular Atrophy / Q000473:pathology*; D009206:Myocardium / Q000648:ultrastructure*; D013118:Spinal Cord Diseases / Q000473:pathology*; D013577:Syndrome