title: Scaglietti's method for conservative treatment of simple bone cysts with local injections of methylprednisolone acetate.
abstract: The results of 30 consecutive cases of simple bone cysts treated conservatively by intracystic injections of methylprednisolone acetate (MPA) according to the method of Scaglietti are reported. The injections were given under general or local anaesthesia in doses of 80-200 mgs repeated every 2 months up to a total of 2 or 3 injections, rarely more. The minimum period required for achieving a result is 6 months; but there is a continuation of radiographic improvement for 1 to 2 years. There is complete radiographic cure in about half the cases; in the others there is a substantial improvement which makes surgery unnecessary. We have used this method systematically for 3 years, and out of 42 cases only one required operation because of a displaced subtrochanteric fracture. There was a partial recurrence in one case after apparent radiographic cure. The patients' age does not seem to affect the result but we gained the impression that the effect of MPA is quicker and more reliable in younger patients. Although we do not understand the mechanism of cure in this method it has undoubted advantages over surgery.
mesh_terms: D000293:Adolescent; D000328:Adult; D001845:Bone Cysts / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D005122:Exudates and Transudates; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008297:Male; D008722:Methods; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D013396:Suction
chemical_list: D008775:Methylprednisolone