title: Adrenergic activity and intraocular pressure.
abstract: Systemically-administered noradrenaline lowers intraocular pressure; isoproterenol, similarly administered, has an intraocular pressure-raising effect. Unless extremely low doses are used, these effects will be marked by opposite changes in arterial perfusing pressure. Intraocular pressure-regulating mechanisms carry both alpha- and beta-receptors. Stimulation of alpha-receptors decreases intraocular pressure, while stimulation of beta-receptors increases intraocular pressure. Intraocular pressure is under tonic sympathetic influence.
mesh_terms: D000010:Abducens Nerve / Q000601:surgery; D000818:Animals; D002339:Carotid Arteries / Q000502:physiology; D003250:Constriction; D004285:Dogs; D004558:Electric Stimulation; D005703:Gallamine Triethiodide / Q000494:pharmacology; D007429:Intraocular Pressure / Q000187:drug effects*; D007545:Isoproterenol / Q000494:pharmacology; D009638:Norepinephrine / Q000031:analogs & derivatives / Q000494:pharmacology; D009801:Oculomotor Muscles / Q000294:innervation; D011941:Receptors, Adrenergic / Q000502:physiology*; D014630:Vagus Nerve / Q000502:physiology
chemical_list: D011941:Receptors, Adrenergic; D007545:Isoproterenol; D005703:Gallamine Triethiodide; D009638:Norepinephrine