title: [Primary localization of the pathologic process in amyotrophic lateral sclerosis].
abstract: The clinico-electromyographical study was conducted in 120 patients with motor disturbances in amyotrophical lateral sclerosis. Comparing the clinical and electromyographical data in different variants of this disease the authors make a conclusion on the simultaneous damage of peripheral and central mononeurons from the very onset of the disease. Along with this the latter is damaged not only primarily, but secondarily as a result of trans-synaptic degerneration due to pathology of the segmental-nucleus motor cells.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000175:diagnosis* / Q000503:physiopathology; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons; D012021:Reflex, Abnormal; D012023:Reflex, Monosynaptic; D012026:Reflex, Stretch; D013116:Spinal Cord / Q000503:physiopathology; D013577:Syndrome
vernacular_title: O pervichnoĭ lokalizatsii patologicheskogo protsessa pri bokovom amiotroficheskom skleroze.