title: Metabolism of halothane after its repeated administration in man.
abstract: Metabolism of halothane following its repeated administration, was studied in three patients by estimating the blood bromide concentrations before, during and after halothane anaesthesia. In one patient, the blood halothane concentration was measured during and after its administration. The fraction of halothane metabolised was found to be increased after its repeated administration. This was proved by the rapid clearance of halothane and the increased blood bromide concentration.
mesh_terms: D000768:Anesthesia, General; D001965:Bromides / Q000097:blood*; D006221:Halothane / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged
chemical_list: D001965:Bromides; D006221:Halothane