[The possibility of heart-muscle damage through fenoterol (elektrocardiographic and blood-chemistry studies with particular reference to the heart-muscle-specific isoenzym creatinkinase MB.) (author's transl)].
Fifty patients with premature uterine contractions were treated with the uterine relaxant Fenoterol in combination with the calcium antagonist Verapamil. In order to exclude the possibility of myocardial damage, the heart-muscle-specific isoenzym Creatinkinase MB was routinely evaluated, in addition to ECG-checks. In none of the cases could a significant enzyme activity be shown, even in long-term therapy with high doses of Fenoterol.
D000328:Adult; D003402:Creatine Kinase / Q000378:metabolism; D004357:Drug Synergism; D004562:Electrocardiography; D004983:Ethanolamines / Q000009:adverse effects*; D005260:Female; D005280:Fenoterol / Q000009:adverse effects* / Q000627:therapeutic use; D006331:Heart Diseases / Q000139:chemically induced*; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism; D009206:Myocardium / Q000201:enzymology; D009336:Necrosis; D007752:Obstetric Labor, Premature / Q000517:prevention & control; D011247:Pregnancy; D014700:Verapamil / Q000627:therapeutic use
D004983:Ethanolamines; D007527:Isoenzymes; D005280:Fenoterol; D014700:Verapamil; D003402:Creatine Kinase
Zur Frage der Myocardschädigung durch Fenoterol (Klinisch-chemische Untersuchungen unter besonderer Berücksichtigung des herzmuskelspezifischen Creatinkinase-Isoenzyms MB).