[In vivo X-ray fluorescent analysis of iodine concentration in the thyroid (author's transl)].
A simple apparatus was made for the X-ray fluorescent analysis of iodine concentration of the thyroid. The apparatus consists of 241Am gamma-ray source of 300mCi and pure Ge detector of 50mm2X5mm. Diverging collimator was designed to achieve a full view of the thyroid. The detectable concentration was 0.2mg iodine/g tissue assuming the coefficient of variance of 30% and the counting time of 5 minutes. Measurement was performed for autopsied 10 thyroids and the results were in good correlation with those by neutron activation analysis (r=0.93). Iodine concentration ranged 0.3-1.2mg/g (mean 0.6mg/g) and compared well with the data in literatures. This technique is useful for the in vivo measurement of thyroidal iodine content in patients.
D000328:Adult; D000368:Aged; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007455:Iodine / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D013052:Spectrometry, X-Ray Emission / Q000295:instrumentation / Q000379:methods*; D013961:Thyroid Gland / Q000032:analysis*
D007455:Iodine