Prostaglandins and model aspects of thrombosis.
The possible role of prostaglandins (PGs) in thrombosis was determined by examining their effects in models of thrombosis which included platelet aggregation (in vitro), blood flow (in vivo) and thrombus formation (in vivo). It was found that blood flow and thrombosis can be effectively modulated by the various types of prostaglandins produced by the blood and the vascular tissue.
D000818:Animals; D001160:Arterioles / Q000187:drug effects; D001777:Blood Coagulation / Q000187:drug effects; D001783:Blood Flow Velocity; D006224:Cricetinae; D004305:Dose-Response Relationship, Drug; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects; D011453:Prostaglandins / Q000494:pharmacology / Q000502:physiology*; D013927:Thrombosis / Q000503:physiopathology*
D011453:Prostaglandins