title: Spontaneous hepatic rupture in pregnancy.
abstract: Hepatic rupture as a late complication of toxemic pregnancy is a rare yet lethal condition requiring rapid recognition and surgical management. The clinical triad of toxemia, right upper quadrant pain, and sudden hypotension is the diagnostic hallmark of presentation. Most patients present near the time of delivery and are found to have subcapsular hematomas of the right hepatic lobe with free rupture into the peritoneal cavity and resultant exsanguinating hemorrhage. The association of toxemia and disseminated intravascular coagulation with secondary microembolic damage to the liver and other organs has been discussed. Basic surgical principles in the managment of hepatic subcapsular hematomas, and the prolonged postoperative course and frequent complications in these patients have been stressed.
mesh_terms: D000328:Adult; D001803:Blood Transfusion; D005260:Female; D006406:Hematoma / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008107:Liver Diseases / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D009336:Necrosis; D011225:Pre-Eclampsia / Q000150:complications / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications; D012422:Rupture, Spontaneous