Haemostatic and complement changes in a family with 'allergic' disorders.
A family with allergic manifestations, haemostatic disturbances, total absence of haemolytic activity of the complement system and low IgG levels is described. It is suggested that this functional abnormality of the complement system and the decreased level of immunoglobulin G may be due to immune complex reactions.
D000293:Adolescent; D000328:Adult; D000799:Angioedema / Q000235:genetics; D000936:Antigen-Antibody Complex; D001779:Blood Coagulation Factors; D003174:Complement C1 Inactivator Proteins / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D003165:Complement System Proteins; D005260:Female; D006461:Hemolysis; D006801:Humans; D006967:Hypersensitivity / Q000097:blood / Q000235:genetics* / Q000276:immunology; D007074:Immunoglobulin G / Q000032:analysis; D007705:Kinins / Q000032:analysis; D008297:Male; D006255:Rhinitis, Allergic, Seasonal / Q000235:genetics
D000936:Antigen-Antibody Complex; D001779:Blood Coagulation Factors; D003174:Complement C1 Inactivator Proteins; D003181:Complement C4; D007074:Immunoglobulin G; D007705:Kinins; D003165:Complement System Proteins