title: [Rheumatoid factors in Basedow's disease].
abstract: In patients with untreated Basedow's disease rheumatoid factors were determined by Waaler-Rose and Latex tests. The Waaler-Rose test was positive in 61.5% of 143 cases. After the acute disease stage settled the titers fell in more than 90% of the re-tested cases. In 50% the decrease in titre was of two dilutions or more. The Latex test was carried out in 152 patients. It was positive in 9.2% of the cases and became negative in 50% of the cases after the acute disease stage settled. In 5 out of 6 patients in whom the test remained positive there was in addition a rheumatic disease. The detectable rheumatoid factors are regarded as auto-antibodies against immuno-globulins. This suggests that polyarthritis in Basedow's disease is based on the same pathogenetic mechanisms as rheumatoid arthritis.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000918:Antibody Specificity; D001172:Arthritis, Rheumatoid / Q000209:etiology; D001323:Autoantibodies / Q000032:analysis; D002648:Child; D005260:Female; D006111:Graves Disease / Q000150:complications / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012217:Rheumatoid Factor / Q000032:analysis*
chemical_list: D001323:Autoantibodies; D007136:Immunoglobulins; D012217:Rheumatoid Factor
vernacular_title: Rheumafaktoren beim Morbus Basedow.