[HL-A-B 27 in Reiter's disease with special reference to oligosymptomatic course forms].
In 21 patients with the clinical suspicion of oligosymptomatic R.S.), 21 patients with the clinical suspicion of oligosymptomatic R.S. and 16 patients with recurrent non-gonococcal urethritis 23 HLA-antigens were assessed using a lymphocyte toxicity test. 413 blood donors served as a controll group. 85,7% of the patients with R.S. had phenotyp HLA-B 27 compared with 7,4% of the controll persons. The group with the suspicion of R.S. exhibited with 57,1% a marked increased incidense of HLA-B 27 as well. Compared to this, the HLA-B 27 frequency in the patients with recurrent non-gonococcal urethritis was with 6,3% in especially of its oligosymptomatic courses. Because of the close association between HLA-B 27 and R.S. determination of histocompatibility antigens proved to be a valuable tool in the diagnosis of Reiter's disease, especially of its oligosymptomatic courses.
D000293:Adolescent; D000328:Adult; D016918:Arthritis, Reactive / Q000175:diagnosis* / Q000235:genetics; D003601:Cytotoxicity Tests, Immunologic; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D012737:Sex Factors
D006680:HLA Antigens
HLA-B 27 bei Morbus Reiter unter besonderer Berücksichtigung oligosymptomatischer Verlaufsformen.