Radioimmunoassay of main urinary metabolite of prostaglandin F2alpha in normal subjects.
Radioimmunoassay of 5alpha, 7alpha-dihydroxy-11-keto-tetranor-prosta-1,16-dioic acid, main urinary metabolite of prostaglandin F2alpha (PGF2alpha-MUM), was performed in normal subjects. Twenty-four hours secretion of PGF2alpha-MUM were 29.04 +/- 9.73 microgram in males and 18.22 +/- 5.88 microgram in females on an average. And an oral administration of aspirin resulted in the remarkable decrease of PGF2alpha-MUM in both sexes.
D001241:Aspirin / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D011460:Prostaglandins F / Q000378:metabolism / Q000652:urine*; D011863:Radioimmunoassay; D012737:Sex Factors
D011460:Prostaglandins F; D001241:Aspirin