title: Hemofiltration: treatment of renal failure by ultrafiltration and substitution.
abstract: Hemofiltration, in contrast to hemodialysis or peritoneal dialysis, eliminates toxic substances accumulated in uremia by a process that is independent of molecular weight. By means of a special device, the ultrafiltrate of blood is replaced, up to the desired amount, by a modified Ringer's lactate solution. The application of this new method results in better control of severe hypertension, and controls calcium phosphate and lipid metabolism in a more physiologic manner than dialysis does, without additional drug therapy being necessary. Smaller amounts of fluid and a simplification of devices improve hygienic conditions and patient mobility.
mesh_terms: D001794:Blood Pressure; D001835:Body Weight; D006400:Hematocrit; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D007773:Lactates; D008970:Molecular Weight; D009994:Osmolar Concentration; D006435:Renal Dialysis; D014462:Ultrafiltration
chemical_list: D007773:Lactates