Metabolic energy requirements during teleost melanophore adaptations.
Inhibition of oxidative phosphorylation by 2,4-dinitrophenol or sodium cyanide promotes complete melanosome aggregation in teleost melanophores. This aggregation is not promoted via the alpha-sympathetic receptor sites because it occurs in the presence of tolazoline hydrochloride, an alpha-receptor blocking agent. Interpretation of these results suggests metabolic energy release is required in the centrifugal direction only.
D000818:Animals; D002449:Cell Aggregation / Q000187:drug effects; D003486:Cyanides / Q000494:pharmacology; D004140:Dinitrophenols / Q000494:pharmacology; D004734:Energy Metabolism; D005399:Fishes; D008547:Melanophores / Q000378:metabolism*; D010085:Oxidative Phosphorylation / Q000187:drug effects; D014043:Tolazoline / Q000494:pharmacology
D003486:Cyanides; D004140:Dinitrophenols; D014043:Tolazoline