Histocompatibility antigens in vertebral ankylosing hyperostosis.
All known A, B, and C HLA antigens were determined in 50 white patients with vertebral ankylosing hyperostosis. A statistically significant decrease was found for the A9 and A11 specificities. Only three (6%) of the patients possessed the B27 antigen, a frequency which is not different from that of a control population. B27 therefore does not seem to be linked to abundant new bone formation.
D000328:Adult; D000368:Aged; D000844:Ankylosis / Q000276:immunology*; D001848:Bone Diseases, Developmental / Q000276:immunology*; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013122:Spinal Diseases / Q000276:immunology*
D006680:HLA Antigens