title: 1alpha-hydroxyvitamin D3 in primary hyperparathyroidism.
abstract: The surgical management of primary hyperparathyroidism with severe bone disease (and tertiary hyperparathyroidism) has frequently been complicated by severe and prolonged post-operative hypocalcaemia. In seven such cases a short-pre-operative course of 1alpha-hydroxyvitamin D3 has been found to abolish these adverse features virtually completely and even to diminish pre-operative symptoms where present. Exacerbation of hypercalcaemia has not occurred and this regimen is thus recommended as a routine measure.
mesh_terms: D000328:Adult; D002118:Calcium / Q000378:metabolism; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use*; D006961:Hyperparathyroidism / Q000601:surgery*; D006996:Hypocalcemia / Q000188:drug therapy*; D007085:Ilium / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010280:Parathyroid Glands / Q000601:surgery; D011183:Postoperative Complications / Q000188:drug therapy*
chemical_list: D006887:Hydroxycholecalciferols; D002118:Calcium