Striated muscle cells in the leptomeninges in cerebral dysplasia.
Non-neoplastic foci of skeletal muscle cells are rarely noted within human central nervous system. This report describes two children with developmental anomalies and striated muscle in the leptomeninges. Embryological displacement of notochordal or prechordal mesoderm in certain types of cranio-vertebral-cerebral dysplasia may account for the origin, the restricted sites and the infrequent observation of leptomeningeal striated muscle cells.
D000015:Abnormalities, Multiple / Q000473:pathology; D000293:Adolescent; D001099:Arachnoid / Q000648:ultrastructure*; D001921:Brain / Q000002:abnormalities* / Q000473:pathology; D004200:Diseases in Twins; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009132:Muscles / Q000648:ultrastructure*; D010841:Pia Mater / Q000648:ultrastructure*; D016136:Spina Bifida Occulta / Q000473:pathology*; D013116:Spinal Cord / Q000473:pathology