The effect of epinephrine on tracheal fluid flow and surfactant efflux in fetal sheep.
A marked decrease in fetal tracheal fluid flow and an increase in pulmonary surfactant efflux were found after infusion of epinephrine into fetal sheep. The data suggest that endogenous catecholamines may play a role in preparing the fetal lung for birth.
D000818:Animals; D001826:Body Fluids / Q000502:physiology*; D004837:Epinephrine / Q000008:administration & dosage / Q000494:pharmacology*; D005333:Fetus / Q000502:physiology*; D005865:Gestational Age; D007263:Infusions, Parenteral; D008168:Lung / Q000196:embryology* / Q000378:metabolism; D010713:Phosphatidylcholines / Q000032:analysis; D011663:Pulmonary Surfactants / Q000378:metabolism*; D012756:Sheep; D013997:Time Factors
D010713:Phosphatidylcholines; D011663:Pulmonary Surfactants; D004837:Epinephrine