title: Cytogenetic study of 10 cases of infectious mononucleosis.
abstract: Cytogenetic analysis of 10 cases of infectious mononucleosis has revealed increased damage in the form of chromosome breakage and aberrations typical of viral infection, but in addition a few cells were consistently found to harbour a deleted number 22, similar tsponse to the mitogen phytohaemagglutinin is suggested. This inhibitor appears to have a reversible action on the patient's own lymphocytes but no inhibitory effect on control lymphocytes.
mesh_terms: D000293:Adolescent; D000328:Adult; D002869:Chromosome Aberrations; D002872:Chromosome Deletion; D002904:Chromosomes, Human, 21-22 and Y; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007244:Infectious Mononucleosis / Q000097:blood / Q000235:genetics*; D008213:Lymphocyte Activation; D008297:Male