[The effect of tramadol and other analgesics on the pain threshold in human dental pulp (author's transl)].
In 60 young, healthy volunteers the analgesic efficacy of 1-(m-methoxyphenyl)-2-(dimethylaminomethyl)-cyclohexan-1-ol (tramadol; Tramal), dextropropoxyphene and a commercial drug mixture (acetylsalicylic acid 200 mg; phenacetin 200 mg; codeine phosphor. 10 mg; caffeine anhydr. 50 mg; phenobarbital 25 mg) was investigated by determining the pain threshold in dental pulp. All three drugs increased the pain threshold considerably but there was no difference in the analgesic effect of the three drugs.
D000328:Adult; D000700:Analgesics / Q000009:adverse effects / Q000494:pharmacology*; D003511:Cyclohexanols / Q000009:adverse effects / Q000494:pharmacology*; D003782:Dental Pulp / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D010146:Pain / Q000503:physiopathology*; D013997:Time Factors
D000700:Analgesics; D003511:Cyclohexanols
Beeinflussung der Schmerzschwelle an der Zahnpulpa durch Tramadol und andere Analgetika.