[Acute pituitary failure as the presentation of a prolactin cell adenoma during a pregnancy made possible by bromocriptine (author's transl)].
A 21-year-old woman had sterility due to amenorrhoea-galactorrhoea with hyperprolactinaemia and hypoplastic ovaries. The sella turcica was asymmetrical but tomograms were suggestive of a congenital appearance. There was no suprasellar expansion. Treatment with bromocriptine and HMG resulted in pregnancy. Acute pituitary failure occurred at the 10th week, revealing an adenoma. The pregnancy proceeded to term after hypophysectomy. This complication, the first reported under the effects of bromocriptine, may serve as a reminder of the precautions to be taken during pregnancy in a hyperprolactinaemic woman.
D000236:Adenoma / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D000328:Adult; D000568:Amenorrhea / Q000150:complications / Q000188:drug therapy; D001971:Bromocriptine / Q000627:therapeutic use*; D005132:Eye Manifestations; D005260:Female; D005687:Galactorrhea / Q000150:complications; D006801:Humans; D007016:Hypophysectomy; D007247:Infertility, Female / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000503:physiopathology; D011388:Prolactin / Q000378:metabolism*
D001971:Bromocriptine; D011388:Prolactin
Apoplexie hypophysaire révélatrice d'un adénome à cellules prolactiniques au cours d'une grossesse permise par la bromocriptine.