Graves' disease, follicular thyroid carcinoma and functioning pulmonary metastases.
We present a case with the unusual association of Graves' disease and functioning pulmonary metastases of follicular thyroid carcinoma. Unlike other reports of thyroid cancer and thyrotoxicosis, this patient's hyperthyroidism was related to a hyperfunctioning primary thyroid neoplasm and not merely to large amounts of functioning metastatic tumor. Thyroidectomy cured her hyperthyroidism. A lung biopsy confirmed the impression of metastatic thyroid cancer. Following therapeutic radioactive I131 pulmonary metastases completely disappeared.
D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D000328:Adult; D005260:Female; D006111:Graves Disease / Q000150:complications*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D009362:Neoplasm Metastasis; D013964:Thyroid Neoplasms / Q000150:complications* / Q000473:pathology