3alpha-Hydroxy-5beta,14beta-chol-8-en-24-oic acid and its isomer, dehydration products of chenodeoxycholic acid obtained by treatment with concentrated HC1.
3alpha, 7alpha-Dihydroxy-5beta-cholan-24-oic acid in acetic acid was treated with concentrated hydrochloric acid at room temperature. Two of the dehydration products thus obtained proved to correspond to the beta- and gamma-acids reported (5). One (gamma-acid) of these was identified as 3alpha-hydroxy-5beta, 14beta-chol-8-en-24-oic acid (IIa) by means of several spectral measurements of itself and its OsO4 oxidation products. Chemical structure of the other (beta-acid) remains undetermined.
D055598:Chemical Phenomena; D002621:Chemistry; D002635:Chenodeoxycholic Acid; D002770:Cholenes; D002849:Chromatography, Gas; D007536:Isomerism; D013058:Mass Spectrometry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D002770:Cholenes; D002635:Chenodeoxycholic Acid