title: Diagnosis of food allergy through bronchial challenge.
abstract: Bronchial provocation tests were performed in 48 children whose skin tests were positive to food extracts or in cases in which anamnestic data suggested food allergy. In 20 cases a marked change of dynamic compliance, vital capacity or FEV1 could be demonstrated within 1--5 minutes after the inhalation of food extracts. Ten of them had bronchoconstriction after milk or egg; 5 among them had negative skin tests. Twenty patients were examined before and after 1--3 hours after the ingestion of 300 ml. of milk. Five of them showed definite decrease of FEV1, whereas the vital capacity did not change. It is concluded that food allergy can be established as the cause of bronchoconstriction in 5--10% of asthmatic children.
mesh_terms: D000293:Adolescent; D000485:Allergens; D000818:Animals; D001249:Asthma / Q000150:complications* / Q000276:immunology; D001980:Bronchi / Q000276:immunology; D001986:Bronchial Spasm / Q000209:etiology* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D004531:Eggs; D005512:Food Hypersensitivity / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008892:Milk; D012882:Skin Tests; D013147:Spirometry
chemical_list: D000485:Allergens