[The effect of carbenoxolone on stress ulcers in rats].
By an immobilisation with a 72 hour's interruption of intake of fluid and nutrition stress ulcers were produced in the stomach of Wistar rats. Through a sound 34 animals received daily 25 mg/kg/body weight carbenoxolon. In them ulcers were found in nearly the same number as in the 30 controls. A conspicuous accumulation of ulcers in the pre-stomach or glandular stomach was not observed. A protective effect of the carbenoxolon could not be proved.
D000818:Animals; D002229:Carbenoxolone / Q000627:therapeutic use*; D004341:Drug Evaluation; D010437:Peptic Ulcer / Q000188:drug therapy*; D051381:Rats; D014315:Triterpenes / Q000627:therapeutic use*
D014315:Triterpenes; D002229:Carbenoxolone
Der Einfluss von Carbenoxolon auf das Stressulkus der Ratte.