[Demonstration of a new analytical grading system for the determination of pheochromocytoma within the scope of hypertension control].
The problems of the phaeochromocytoma are in its rareness, its appearance--every patient with hypertension can be a carrier of a phaeochromocytoma--, its localisation--10% are situated outside the adrenal glands--, its operability with following permanent normalisation of the pressure. As hypertension is very frequent and the diagnostics is very expensive the finding of carriers of phaeochromocytomas is possible only by means of screening methods. Thus cases with an urgent suspicion are found. Such a method is described, the basis of which is a semiquantitative determination of the vanillic amygdalic acid. Instead of the usually used diazocolour-reagent in connection with a non-optimal buffer a complete nitrophenylantiazotate with a buffer of high ionic strength is taken. The pH-value 10 of the urine which is to be demanded for the colour reaction is thus reached in every case. In order to avoid falsely normal results with every urinary test a preparation with added vanillic amygdalic acid is performed and thus the presence of colour inhibitors is recognized. If the result is pathological a quantitative determination is necessary.
D000310:Adrenal Gland Neoplasms / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000517:prevention & control*; D010673:Pheochromocytoma / Q000175:diagnosis*
Darstellung eines neuen analytischen Stufensystems zur Erfassung des Phäochromozytoms im Rahmen der Hypertoniebekämpfung.