[Uteroplacental blood flow in normal pregnancy before and after short-term treatment with (isoxsuprine) beta-sympathicomimetica (author's transl)].
The uteroplacental blood flow was measured in 26 normal pregnant women between the 36-43 weeks of pregnancy before and after a short-term treatment of isoxsuprine. The patients had no complications of pregnancy and no uterine contractions during this time. We used our intravenous Xe-133 method for measuring the intervillous and myometrial perfusion (20). During the blood flow measurements we also measured maternal arterial blood pressure and heart rate. To evaluate the short-term treatment effect of isoxsurpine we applied an intravenous injection or infusion. The placental flow was (124 +/- 32) before and (117 +/- 39) ml/min/100 ml after isoxsuprine application. The corresponding values for myometrial flow were (7,8 +/- 3,5) and (6,2 +/- 3,0) ml/min/100 g. The pathological changes of the uterplacental blood flow with vena caval syndrom will referred in text. There was a statistically significant increase in maternal heart rate and a decrease in blood pressure.
D000328:Adult; D005260:Female; D005333:Fetus / Q000502:physiology; D006801:Humans; D007556:Isoxsuprine / Q000494:pharmacology*; D008431:Maternal-Fetal Exchange / Q000187:drug effects*; D010920:Placenta / Q000098:blood supply*; D011247:Pregnancy; D012039:Regional Blood Flow / Q000187:drug effects; D014599:Uterus / Q000098:blood supply* / Q000502:physiology
D007556:Isoxsuprine
Uteroplazentare Perfusion bei normalen Schwangerschaften vor und nach Kurzzeit-Therapie mit (Isoxsuprin) Beta-Sympathiekomimetika.