The close interrelationship between increased vascular retinal permeability and blood pressure level. Evidence from retinal fluorangiography.
A long-term study was done by means of interative fluorangiography on microvascular retinal permeability versus the blood pressure control carried out in 11 patients with a diastolic blood pressure of greater than or equal to 130 mm Hg and with retinal exudates, haemorrhages and oedema. No matter what the original disease was (i.e., essential, renovascular, endocrine hypertension or chronic nephropathy with terminal renal failure) the increased permeability appeared to be critically connected with the blood pressure level. Our results confirm that hypertension per se might be the cause of vascular permeability changes.
D000328:Adult; D001794:Blood Pressure; D002199:Capillary Permeability; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D006974:Hypertension, Malignant / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010211:Papilledema / Q000503:physiopathology; D012164:Retinal Diseases / Q000503:physiopathology*; D012166:Retinal Hemorrhage / Q000503:physiopathology; D012171:Retinal Vessels / Q000503:physiopathology*