Spinal calcium changes with 1alpha-hydroxyvitamin D3.
During treatment of renal osteodystrophy with 1alpha-hydroxyvitamin D3 in eleven patients, regional changes in the skeleton have been compared with long-term calcium balance as assessed by whole-body calcium. Radial bone changes did not correlated well with calcium balance, but spinal calcium changes were of a similar magnitude when changes were large. Bone alkaline phosphatase changes correlated well with changes in spinal calcium, but less well with changes in radial bone density.
D000469:Alkaline Phosphatase / Q000032:analysis; D002118:Calcium / Q000032:analysis*; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use*; D008297:Male; D009501:Neutron Activation Analysis; D011884:Radius / Q000032:analysis; D013131:Spine / Q000032:analysis*
D006887:Hydroxycholecalciferols; D000469:Alkaline Phosphatase; D002118:Calcium