Edema formation and neutrophil mobilization in the neutropenic rat.
The relationship between leucocyte mobilization and edema formation was evaluated in the carrageenan pleurisy model. In normal rats carrageenan was able to mobilize between 80 and 100 million cells per ml of fluid. In neutropenic rats the concentration fell to between 20 and 50 million cells per ml, suggesting the edema formed after carrageenan injection is not directly correlated with cellular mobilization.
D000380:Agranulocytosis / Q000150:complications*; D000818:Animals; D002351:Carrageenan; D003520:Cyclophosphamide; D004487:Edema / Q000139:chemically induced*; D005260:Female; D009503:Neutropenia / Q000139:chemically induced / Q000150:complications*; D009504:Neutrophils; D051381:Rats
D003520:Cyclophosphamide; D002351:Carrageenan