99Tcm-DP accumulation in rabbit skull bones after 60Co gamma irradiation.
Histology demonstrated new bone formation and bone destruction in rabbit mandibles irradiated with 20 Gy in a single exposure, but no abnormality following 10 Gy in a single exposure. Gamma camera examination of the 99Tcm-DP distribution could not demonstrate any abnormalities, and is concluded not to be effective in demonstrating early radiation injury to bone tissue. Radiation therapy is considered a negligible source of false positive findings in scintigraphy of the facial skeleton.
D000818:Animals; D001862:Bone Resorption / Q000528:radiation effects; D003037:Cobalt Radioisotopes; D005720:Gamma Rays; D008334:Mandible / Q000473:pathology / Q000528:radiation effects; D008336:Mandibular Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D010006:Osteoblasts / Q000528:radiation effects; D010012:Osteogenesis / Q000528:radiation effects; D010025:Osteoradionecrosis / Q000175:diagnosis* / Q000473:pathology; D011817:Rabbits; D011832:Radiation Injuries / Q000175:diagnosis*; D011877:Radionuclide Imaging; D012886:Skull / Q000000981:diagnostic imaging / Q000528:radiation effects*; D013667:Technetium; D013997:Time Factors
D003037:Cobalt Radioisotopes; D013667:Technetium