Re-examination of small intestinal disposal of Vibrio cholerae in mice.
The rapid disposal of antibody-treated vibrios by peristalsis in whole animal models makes it difficult to obtain clear evidence for a simultaneous intra-intestinal bactericidal effect. In this paper we have re-examined the evidence for direct intra-intestinal killing. We have found that the data can be explained adequately by peristaltic effects without postulating a direct bactericidal action in vivo.
D000818:Animals; D000831:Animals, Newborn / Q000382:microbiology; D000907:Antibodies, Bacterial; D004064:Digestive System / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D005260:Female; D007109:Immunity; D007413:Intestinal Mucosa / Q000382:microbiology; D007421:Intestine, Small / Q000276:immunology* / Q000382:microbiology; D008297:Male; D051379:Mice; D010528:Peristalsis; D014734:Vibrio cholerae / Q000276:immunology* / Q000302:isolation & purification
D000907:Antibodies, Bacterial