Desipramine and some other antidepressant drugs decrease the major norepinephrine metabolite 3,4-dihydroxyphenylglycol-sulphate in the rat brain.
D015102:3,4-Dihydroxyphenylacetic Acid / Q000378:metabolism; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001923:Brain Chemistry / Q000187:drug effects*; D003891:Desipramine / Q000494:pharmacology*; D004298:Dopamine / Q000378:metabolism; D006018:Glycols / Q000378:metabolism*; D006719:Homovanillic Acid / Q000378:metabolism; D008297:Male; D009638:Norepinephrine / Q000378:metabolism*; D009647:Normetanephrine / Q000378:metabolism; D051381:Rats; D012110:Reserpine / Q000494:pharmacology; D013997:Time Factors; D014443:Tyrosine / Q000494:pharmacology
D000928:Antidepressive Agents; D006018:Glycols; D009647:Normetanephrine; D015102:3,4-Dihydroxyphenylacetic Acid; D014443:Tyrosine; D012110:Reserpine; D003891:Desipramine; D004298:Dopamine; D009638:Norepinephrine; D006719:Homovanillic Acid