[Formation of diploids by Aspergillus niger and their biosynthesis of citric acid].
Diploid organisms appeared spontaneously in heterokaryons of Aspergillus niger produced by crossing a beige mutant, which was adenine-deficient, and a green mutant requiring the addition of yeast autolysate. The frequency of diploidization increased two-fold under the action of colchicine (0.5%). The diploids became prototrophous, the colour of their conidia increased 1.5--2.4 times. The rate of production of citric acid by the diploid strains which had originated under the action of colchinine was 1.5 times higher than that of the parent haploid mutants.
D001234:Aspergillus niger / Q000166:cytology / Q000235:genetics* / Q000378:metabolism; D002951:Citrates / Q000096:biosynthesis*; D003078:Colchicine / Q000494:pharmacology; D003433:Crosses, Genetic; D004171:Diploidy; D009154:Mutation; D013045:Species Specificity
D002951:Citrates; D003078:Colchicine
Obrazovanie diploidov u Aspergillus niger i biosintez imi limonnoĭ kisloty.