title: The stability of standards for radioimmunoassay of human TSH: research standard A and the international reference preparation initially 68/38.
abstract: The stability of the International Reference Preparation of human TSH for immunoassay (previously distributed in ampoules coded 68/38) and of Research Standard A for HTSH has been examined by radioimmunoassay of accelerated degradation samples (stored as the dry ampouled preparations). Potency estimates on degradation samples suggest a high order of stability of immunopotency recognisable by two antisera (MRC 72/356 and Hunter 3A). For the International Reference Preparation the loss of immunopotency during storage at -20 degrees C is predicted to have been 0.56% per year.
mesh_terms: D004355:Drug Stability; D004356:Drug Storage; D006801:Humans; D007106:Immune Sera; D011863:Radioimmunoassay; D013696:Temperature; D013972:Thyrotropin / Q000032:analysis* / Q000276:immunology / Q000592:standards
chemical_list: D007106:Immune Sera; D013972:Thyrotropin