Immunodepression, ascites tumour and lactate dehydrogenase virus.
The delayed hypersensitivity (DH) response to picryl chloride was studied in Ehrlich ascites tumour-bearing and normal control mice. A significant depression of the DH response was found in the tumour-bearing mice, which was associated with a marked elevation of serum lactate dehydrogenase (LDH). Depression of DH was also observed in mice receiving cell-free ascitic fluid. These mice also showed an elevated serum LDH which is assumed to be associated with the lactate dehydrogenase virus. A method for assaying DH in vivo is described.
D000818:Animals; D001202:Ascitic Fluid / Q000276:immunology; D002286:Carcinoma, Ehrlich Tumor / Q000150:complications / Q000276:immunology*; D004431:Ear, External / Q000276:immunology; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007772:Lactate dehydrogenase-elevating virus / Q000276:immunology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D014777:Virus Diseases / Q000150:complications
D007770:L-Lactate Dehydrogenase