[Glycoprotein changes in acute myocardial infarction (author's transl)].
The changes of 11 plasma glycoproteins have been recorded during the first month in 22 patients with acute myocardial infarction; the quantitations have been performed by radial immunodiffusion on plates. The IgM proteins are significantly augmented and, with lesser degree, the alpha1 acid glycoprotein, the alpha1 antitrypsin and the haptoglobin are significantly augmented too. The peak is noted on the tenth day (the alpha1 acid glycoprotein only has its peak in twentieth day). To explain these changes we can consider: 1) the inflammatory reaction; 2) the repair reaction; 3) the autoimmune response. The complete explanation of these findings needs time: in the mean time we could use the IgM changes as a test in the second stage diagnosis of the acute myocardial infarction as well as the tests used so far.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D005260:Female; D006023:Glycoproteins / Q000097:blood*; D006242:Haptoglobins / Q000032:analysis; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D012712:Serum Globulins / Q000032:analysis
D006023:Glycoproteins; D006242:Haptoglobins; D007136:Immunoglobulins; D012712:Serum Globulins
Modificazioni dell'assetto glicoproteico durante la fase acuta dell'infarto miocardico.