Plasmatic heparinic activity following lipid load.
Changes of hemocoagulability and of plasmatic fibrinolysis have induced us to study PHA following the administration of the lipid load. We have studied the effects induced by the administration of a lipid load, constituted by 1/2 g of olive oil and by 1/2 g of butter dissolved in 200 ml of vaccine milk. PHA has been estimated in all our subjects under basal conditions and after 4 1/2 hours from the lipid load. The statistical analysis of the results we have obtained shows a significant PHA reduction following the lipid load. Concluding, our results indicates that the lipid load very frequently causes a reduction of PHA which is due to a consumption of heparin. This consumption is more probably due to the activation of lipoprotein-lipase by heparin.
D000818:Animals; D002079:Butter; D004041:Dietary Fats / Q000494:pharmacology*; D006493:Heparin / Q000097:blood*; D006801:Humans; D008892:Milk; D009821:Oils / Q000494:pharmacology
D004041:Dietary Fats; D009821:Oils; D002079:Butter; D006493:Heparin