[Investigations on the relationship between intraocular pressure and perifoveal capillary circulation in glaucoma patients using the entoptic blood corpuscle phenomenon (author's transl)].
Blood circulation in the central retina was examined in 30 eyes suffering from glaucoma, using the entoptic phenomenon to count leucocytes travelling through the retinal capillaries in the macula area. Two measurements were taken for each eye at different intraocular pressure levels and the results were compared with each other. They showed that reduction of an originally high intraocular tension level significantly increased the blood flow. In a control group of healthy eyes in a similar group of patients insignificant changes in blood flow were recorded. There was thus a direct linear relationship between reduction of intraocular pressure and relative increase in blood flow with a strongly positive correlation (r = 0,74). Hence an effective autoregulation of blood flow in relation to changes in intraocular pressure could not be demonstrated.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002196:Capillaries / Q000503:physiopathology; D005260:Female; D005654:Fundus Oculi; D005901:Glaucoma / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D007429:Intraocular Pressure; D007958:Leukocyte Count; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D055095:Optics and Photonics / Q000295:instrumentation*; D012171:Retinal Vessels / Q000503:physiopathology*; D014788:Vision, Entoptic
Untersuchungen über die Beziehungen der zentralen kapillaren Retinadurchblutung zur Augendruckhöhe bei Glaukompatienten mit Hilfe der entoptisch sichtbaren Blutbewegung.