Multicenter two-dose trials of bivalent influenza A vaccines in asthmatic children aged six to 18 years.
Data from all of the vaccination centers that immunized asthmatic children six to 18 years old with bivalent influenza A/New Jersey/76 and A/Victoria/75 vaccines were analyzed. Systemic reaction indexes were somewhat higher in asthmatic children receiving the first dose of whole-virus vaccines than in similar vaccinees without asthma. Antibody levels after immunization, while different in some instances, did not show any significant trends toward either hypo- or hyperresponsiveness in the asthmatic children.
D000293:Adolescent; D000914:Antibodies, Viral / Q000096:biosynthesis; D001249:Asthma / Q000276:immunology*; D002648:Child; D004306:Dose-Response Relationship, Immunologic; D006801:Humans; D009980:Influenza A virus / Q000276:immunology; D007252:Influenza Vaccines / Q000009:adverse effects / Q000494:pharmacology*
D000914:Antibodies, Viral; D007252:Influenza Vaccines