title: [Clinico-diagnostic considerations on lymphocytic thyroiditis. Presentation of clinical cases].
abstract: Personal experience with autoimmune lymphocyte thyroiditis, represented by 11 cases observed between 1972 and today, is reported. After some brief aetiopathogenetic notes on the lesions in question, the problems of diagnosing the nature of the thyropathy are stressed. After reviewing the examinations that have been proposed in the literature, it is noted that the preoperative recognition of a thyroiditis with autoimmune genesis is still problematical. The institution of a diagnostic protocol based on the systematic search for antibodies, the perchlorate test, the thyrostimulation test, ESR study, the search for alpha2 and gamma-globulins, scintigraphy with positive indicators and needle biopsy as well as on scintigraphy and thyrometabolic tests (T3-T4-TSH-TRH test) is proposed. Even when such a protocol is adopted, however, it should be mentioned that only in 18% of the personal cases was it possible to diagnose thyroiditis, in the other subjects this being merely an occasional post-operative finding. In confirming the personal therapeutic approach, which at least initially is medical, for recognized forms, it is pointed out that surgical treatment is to be preferred in certain cases because of the presence of compressive phenomena, and in others it appears capable of relieving, in follow-up, the thyroiditic process, probably as a result of the removal of the antigenic tissue.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000906:Antibodies / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D013961:Thyroid Gland / Q000473:pathology; D013963:Thyroid Hormones / Q000032:analysis; D013964:Thyroid Neoplasms / Q000175:diagnosis; D013966:Thyroiditis / Q000175:diagnosis; D013967:Thyroiditis, Autoimmune / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology
chemical_list: D000906:Antibodies; D001323:Autoantibodies; D007136:Immunoglobulins; D013963:Thyroid Hormones
vernacular_title: Considerazioni clinico-diagnostiche sulle tiroiditi linfocitarie. Presentazione di casi clinici.