Chronic treatment with desipramine caused a sustained decrease of 3,4-dihydroxyphenylglycol-sulphate and total 3-methoxy-4-hydroxyphenylglycol in the rat brain.
D015102:3,4-Dihydroxyphenylacetic Acid / Q000378:metabolism; D000639:Amitriptyline / Q000494:pharmacology; D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects*; D002396:Catechols / Q000378:metabolism; D003864:Depression, Chemical; D003891:Desipramine / Q000494:pharmacology*; D004298:Dopamine / Q000494:pharmacology; D005026:Ethylene Glycols / Q000378:metabolism*; D006018:Glycols / Q000378:metabolism*; D006719:Homovanillic Acid / Q000378:metabolism; D007099:Imipramine / Q000494:pharmacology; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000378:metabolism* / Q000031:analogs & derivatives; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D013997:Time Factors; D014443:Tyrosine / Q000494:pharmacology
D002396:Catechols; D005026:Ethylene Glycols; D006018:Glycols; D015102:3,4-Dihydroxyphenylacetic Acid; D000639:Amitriptyline; D014443:Tyrosine; D008734:Methoxyhydroxyphenylglycol; D007099:Imipramine; D003891:Desipramine; C010117:3,4-dihydroxyphenylglycol; D004298:Dopamine; D009638:Norepinephrine; D006719:Homovanillic Acid