[Impulse flow structure following exposure of a cutaneous nerve to nociceptive solutions of potassium chloride].
Using the cross-correlation method, the pattern of impulses flow coding a nociceptive signal is studied in the n. saphenus of the cat. It is found that nociceptive solutions of KCl (125-1000 mM) stimulate both myelinated and nonmyelinated fibres. The flow density increases with time of the stimulation action, reaching a level sufficient for the appearance of nociceptive pressure reflexes. The maximum of these reflexes coincides with the appearance of synchronous pulsations in the group of non-myelinated fibres. Thus a nociceptive signal caused directly by the exposure of the nerve to strong solutions of KCl is coded by a high density of the impulse flow, in which synchronous pulsations are likely to be found.
D000818:Animals; D002415:Cats; D009413:Nerve Fibers, Myelinated / Q000502:physiology; D009619:Nociceptors / Q000502:physiology*; D010146:Pain / Q000139:chemically induced; D010525:Peripheral Nerves / Q000502:physiology*; D011189:Potassium Chloride; D012867:Skin / Q000294:innervation*
D011189:Potassium Chloride
Struktura impul'snogo potoka pri deĭstvii notsitseptivnykh rastvorov khloristogo kaliia na kozhnyĭ nerv koshki.