title: Complement C1-inactivator in the serum of patients with malignant disease.
abstract: Complement C1-inactivator (C1-IA) in serum was determined in 423 individuals. The normal range for the concentration of C1-IA in serum was calculated from values in 94 blood donors and the concentrations in the sera of 329 patients were determined in relation to this range. A significant correlation was found between widespread malignant neoplastic disease and increased quantity of C1-IA in serum. Determination of C1-IA may be used to evaluate the extent to which a malignant disease is disseminated.
mesh_terms: D003174:Complement C1 Inactivator Proteins / Q000097:blood*; D006801:Humans; D007122:Immunoelectrophoresis; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000097:blood*
chemical_list: D003174:Complement C1 Inactivator Proteins