Juvenile diabetes mellitus and optic atrophy.
Nine patients with the syndrome of juvenile diabetes mellitus and optic atrophy exemplified the wide range of manifestations of this syndrome. The disease may occur as a recessively inherited or sporadic disorder and tends to have multi-system involvement. Hearing loss, diabetes insipidus, and evidence of cerebellar or central vesitbulo-ocular dysfunction are common.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000235:genetics / Q000378:metabolism; D005260:Female; D006801:Humans; D007500:Iritis / Q000209:etiology; D007766:Lacrimal Apparatus Diseases / Q000209:etiology; D008297:Male; D000857:Olfaction Disorders / Q000209:etiology; D009896:Optic Atrophy / Q000209:etiology*; D009898:Optic Disk / Q000473:pathology; D011680:Pupil / Q000503:physiopathology; D013577:Syndrome