title: Abnormalities of gastric emptying and pyloric reflux in uncomplicated hiatus hernia.
abstract: We have measured the rate of gastric emptying of solid and liquid meals by an external scanning technique and have studied pyloric reflux by a radiological technique. Investigations were performed in patients with uncomplicated hiatal hernia, patients with uncomplicated duodenal ulcer and normal controls. There was a significant delay in the emptying of both solid and liquid meals in the patients with hiatal hernia compared with both the duodenal ulcer patients (solid meals P less than 0.01, liquid meals P less than 0.025) and with normal controls (solid meals P less than 0.05, liquid meals P less than 0.001). Duodenogastric reflux was observed in 35% of hiatal hernia patients compared with 24% of duodenal  ulcer patients and no incidence in the controls.
mesh_terms: D005746:Gastric Emptying; D006548:Hernia, Diaphragmatic / Q000503:physiopathology*; D006551:Hernia, Hiatal / Q000503:physiopathology*; D006801:Humans; D011708:Pylorus / Q000503:physiopathology*; D013997:Time Factors