[Intraamniotic application of lecithin in pregnant rabbits (author's transl)].
In order to find possibilities to influence therapeutically the respiratory distress syndrom at the premature infant animal experiences were carried out with 14C-lecithine. High pregnant rabbits got 14C-lecithine by intraamnial application. Investigation of the distribution of lecithine in the amniotic fluid and in the fetal organism showed an accumulation of lecithine metabolits in lung and lever tissue.
D000650:Amnion; D000653:Amniotic Fluid / Q000378:metabolism; D000818:Animals; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007267:Injections; D007421:Intestine, Small / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D008431:Maternal-Fetal Exchange; D010713:Phosphatidylcholines / Q000008:administration & dosage / Q000378:metabolism*; D011247:Pregnancy; D011817:Rabbits; D012127:Respiratory Distress Syndrome, Newborn / Q000517:prevention & control
D010713:Phosphatidylcholines
Intraamniale Applikation von Lecithin bei hochträchtigen Kaninchen