Dynamic changes of horse serum T-globulin immunization with snake venoms, tetanus and diphtheria toxoids.
In course of immunizing horses with snake venoms, tetanus and diphtheria toxoids, a new serum component, T-globulin, was formed and migrated between the beta- and gamma-globulins. The T-globulin content was parallel with the antibody titre after the middle course of immunization. There were many components in snake antivenin and T-globulin was composed of most of those components. The components of diphtheria T-globulin were the same as those of crude antitoxin and tetanus T-globulin except one precipitin.
D000818:Animals; D000992:Antitoxins / Q000032:analysis; D000997:Antivenins / Q000032:analysis; D001797:Blood Protein Electrophoresis; D004168:Diphtheria Toxoid / Q000276:immunology*; D006736:Horses / Q000097:blood*; D007114:Immunization; D007122:Immunoelectrophoresis; D012712:Serum Globulins / Q000032:analysis*; D012910:Snake Venoms / Q000276:immunology*; D013745:Tetanus Toxoid / Q000276:immunology*; D013997:Time Factors
D000992:Antitoxins; D000997:Antivenins; D004168:Diphtheria Toxoid; D012712:Serum Globulins; D012910:Snake Venoms; D013745:Tetanus Toxoid