[Lymphokine production in the cell-mediated immune response (author's transl)].
In response to tuberculin, lymphocytes derived from BCG-sensitized guinea pigs elaborated soluble materials capable of inducing some reactions in vitro which correlated with the cell-mediated immune response in vivo. The lymphokine activity of these soluble materials was demonstrated by the following biological effects: macrophage migration inhibition, macrophage aggregation, cytotoxicity to HeLa cells and skin reaction.
D000818:Animals; D001500:BCG Vaccine; D002464:Cell Migration Inhibition; D003601:Cytotoxicity Tests, Immunologic; D006168:Guinea Pigs; D007111:Immunity, Cellular; D008214:Lymphocytes / Q000276:immunology; D008222:Lymphokines / Q000096:biosynthesis*; D008264:Macrophages / Q000276:immunology; D012882:Skin Tests
D001500:BCG Vaccine; D008222:Lymphokines