Urolithiasis associated with hypercalciuria.
Fifty male patients with urolithiasis (UL), associated with idiopathic hypercalciuria (IH), were studied in comparison to a group of 18 male normocalcemic patients with inactive calcium stone disease of unknown etiology. In the group of IH-UL, in addition to hypercaliuria, statistically significant hyperphosphaturia with decreased tubular reabsorption of phosphate and hyperuricemia were observed; there was a tendency to hypophosphatemia although non-significant. In 36% of the IH-UL patients the first episode of renal colic appeared at age 40 to 50. Thirty-eight per cent of the IH-UL patients had recurrent stone formation. Twenty per cent of the IH-UL patients had a family history of urolithiasis. Forty-six per cent of all stones contained oxalate in addition to calcium, and 25% of the stones contained oxalate and phosphate.
D000328:Adult; D000368:Aged; D002118:Calcium / Q000652:urine*; D006801:Humans; D006934:Hypercalcemia; D006961:Hyperparathyroidism / Q000150:complications; D007669:Kidney Calculi / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000097:blood / Q000652:urine; D014527:Uric Acid / Q000097:blood / Q000652:urine
D010710:Phosphates; D014527:Uric Acid; D002118:Calcium