Hepatic clearance of drugs. III. Additional experimental evidence supporting the "well-stirred" model, using metabolite (MEGX) generated from lidocaine under varying hepatic blood flow rates and linear conditions in the perfused rat liver in situ preparation.
D000818:Animals; D066298:In Vitro Techniques; D008012:Lidocaine / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008102:Liver Circulation; D008954:Models, Biological; D010477:Perfusion; D051381:Rats
D008012:Lidocaine