Pyridoxine treatment of galactorrhoea-amenorrhoea syndromes.
The effect of pyridoxine (B6) on galactorrhoea, amenorrhoea, and the galactorrhoea-amenorrhoea syndrome was studied in 22 patients. No consistent change in serum prolactin concentration and no resumption of ovulation were seen during 3 months B6 therapy. Inappropriate lactation ceased in 3 of 10 patients with galactorrhoea alone, and menses were restored in 2 of 9 patients with the galactorrhoea-amenorrhoea syndrome while on B6 therapy. Our results suggest that B6 is not generally effective in  the treatment of galactorrhoea-amenorrhoea syndromes.
D000328:Adult; D000568:Amenorrhea / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D005687:Galactorrhea / Q000188:drug therapy*; D006801:Humans; D007775:Lactation Disorders / Q000188:drug therapy*; D010060:Ovulation / Q000187:drug effects; D011247:Pregnancy; D011388:Prolactin / Q000097:blood; D011736:Pyridoxine / Q000627:therapeutic use*
D011388:Prolactin; D011736:Pyridoxine