Predictive value of renal-vein renin measurements in children with various forms of renal hypertension. An international study.
Renal-vein renin was determined in 55 children with renovascular or renal hypertension, 33 of whom being treated surgically. The overall cure rate after surgery was 87.9%. Of 23 patients having a renal-vein renin ratio greater than 1.5, 20 were operated successfully, but 9 of 10 operated patients with a ratio of less than 1.5 also benefited from surgery. Taking into account the frequency of "false-negative ratios" (27.3%) and the potential risks of catheterization, it is suggested that renal-vein renin measurements are not useful as a routine procedure for investigation of a child with renovascular hypertension.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000097:blood* / Q000601:surgery; D007223:Infant; D007668:Kidney / Q000002:abnormalities; D008297:Male; D012078:Renal Artery Obstruction / Q000097:blood / Q000601:surgery; D012082:Renal Veins; D012083:Renin / Q000097:blood*
D012083:Renin