Frequency discrimination following the selective destruction of cochlear inner and outer hair cells.
Frequency discrimination was measured behaviorally before and after drug-induced lesions of cochlear hair cells in the cat. Discrimination was unaffected by complete loss of outer hair cells provided that at least 50% of inner hair cells were intact. Thus, inner hair cells are important for frequency discrimination, and they can function normally in this regard without the influence of outer hair cells.
D000818:Animals; D001309:Auditory Threshold / Q000502:physiology; D001522:Behavior, Animal / Q000502:physiology; D002415:Cats; D003051:Cochlea / Q000648:ultrastructure; D006198:Hair Cells, Auditory / Q000187:drug effects / Q000502:physiology*; D007612:Kanamycin / Q000494:pharmacology; D008465:Mechanoreceptors / Q000502:physiology*; D010897:Pitch Discrimination
D007612:Kanamycin