The hydrolysis of some L-amino acid-p-nitranilides with the normal and pregnant's serum aminopeptidases.
From 4 serum aminopeptidases (2 of pregnant and 2 of nonpregnant women's sera), the placental lysosomal (mol. wt 320,000) splits Lys-NAp only. B-Cys-NAp is hydrolyzed from the both placental enzymes, i.e. lysosomal and microsomal (mol. wt 145,000) AP. Ala-NAp is split by both nonpregnant serum AP more readily than Leu-NAp.
D000626:Aminopeptidases / Q000097:blood* / Q000378:metabolism*; D005260:Female; D006801:Humans; D010920:Placenta / Q000201:enzymology; D011247:Pregnancy
D000626:Aminopeptidases