[Results of long-term treatment of primary osteoporosis with sodium fluoride (author's transl)].
Twenty-three patients with primary osteoporosis were treated with sodium fluoride over 25 months. Mean total dose was 21 g fluoride. Symptoms, body size, biochemical results, radiological changes and skeletal mineral content as well as bone histomorphometry were evaluated in assessing results of treatment. Accordingly, no advance in the disease process was demonstrable in 13 patients, while there was definite improvement in six, but in four there was further progression.
D001827:Body Height; D005260:Female; D005459:Fluorides / Q000627:therapeutic use*; D006801:Humans; D007085:Ilium / Q000473:pathology; D008297:Male; D008875:Middle Aged; D008903:Minerals / Q000032:analysis; D010024:Osteoporosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D011859:Radiography; D011884:Radius / Q000032:analysis; D012969:Sodium Fluoride / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D013997:Time Factors
D008903:Minerals; D012969:Sodium Fluoride; D005459:Fluorides
Ergebnisse einer Langzeittherapie der primären Osteoporose mit Natriumfluorid.