[Anticoagulation and immunosuppression in rapidly progressive glomerulonephritis of poststreptococcal type (author's transl)].
In the majority of cases acute poststreptococcal glomerulonephritis is characterized by a good prognosis. Only relatively rare courses of this disease with clinical symptoms of rapid progressive glomerulonephritis and morphological signs of extracapillary glomerulonephritis together with crescent formation are sometimes prone to an infavorable outcome. A widely accepted medication does not exist up to now. Our own observations including clinical and morphological follow up studies are suggesting a combination of anticoagulants and immunosuppressive drugs. Indication and usefullness of that regimen are discussed.
D000293:Adolescent; D000925:Anticoagulants / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004176:Dipyridamole / Q000627:therapeutic use; D005921:Glomerulonephritis / Q000188:drug therapy* / Q000209:etiology; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D011507:Proteinuria / Q000175:diagnosis; D013290:Streptococcal Infections / Q000150:complications
D000925:Anticoagulants; D007166:Immunosuppressive Agents; D004176:Dipyridamole; D003520:Cyclophosphamide; D006493:Heparin; D011239:Prednisolone
Antikoagulation und Immunsuppression bei akuter (Poststreptokokken-) Glomerulonephritis mit rapid progressivem Verlauf.