Insulin allergy and insulin resistance: two immunologic reactions.
Insulin allergy and insulin resistance can cause life-threatening problems for diabetic patients. Fortunately, allergic manifestations are usually localized, but increasingly severe local reactions can precede a systemic reaction. How use of newer and purer insulin preparations than those previously available will affect the incidence of immunologic reactions is yet to be determined.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D000937:Antigen-Antibody Reactions; D002417:Cattle; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000276:immunology; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007328:Insulin / Q000009:adverse effects* / Q000276:immunology / Q000627:therapeutic use; D007333:Insulin Resistance; D013552:Swine
D000906:Antibodies; D007074:Immunoglobulin G; D007328:Insulin; D007073:Immunoglobulin E