Comparative bioavailability of elemental iron powders for repair of iron deficiency anemia in rats. Studies of efficacy and toxicity of carbonyl iron.
The rate of hemoglobin repletion in iron-deficient rats was used to measure the bioavailability of several elemental iron powders added to an iron-free nutritionally balanced chow. We used ferrous sulfate as a standard, highly bioavailable control. Of the several powders, carbonyl iron demonstrated the highest bioavailability. Testing elemental iron powders in human diets seems appropriate.
D000747:Anemia, Hypochromic / Q000188:drug therapy*; D000818:Animals; D001682:Biological Availability; D004355:Drug Stability; D006400:Hematocrit; D007501:Iron / Q000378:metabolism / Q000627:therapeutic use* / Q000633:toxicity; D008297:Male; D051381:Rats
D007501:Iron