[Blood cholesterol and hepatic bile secreting function in rats of different ages under normal conditions and after maintenance of an atherogenic diet].
The quantity of bile secreted during 24 hours and the concentration of total bile acids in adult 11--12-months-old and aged 27--29-month-old rats were determined by cannulation of common bile duct. As revealed, the difference in bile acid production and in the concentrations of cholesterol fractions in the liver and plasma between the adult and aged rats on a standard diet was insignificant. But the excretion of bile acids was markedly elevated both in adult and aged rats on atherogenous diet. The level of total and ester cholesterol in the plasma was higher in aged rats than in adult animals.
D000818:Animals; D001646:Bile / Q000378:metabolism*; D001647:Bile Acids and Salts / Q000378:metabolism; D002784:Cholesterol / Q000032:analysis / Q000097:blood*; D004036:Diet, Atherogenic; D008099:Liver / Q000032:analysis / Q000378:metabolism*; D051381:Rats
D001647:Bile Acids and Salts; D002784:Cholesterol
Kholesterin krovi i zhelcheotdelitel'naia funktsiia pecheni krys raznogo vozrasta v norme i pri soderzhanii ikh na aterogennom ratsione.