Studies on the etiology of the experimental neuropathy from industrial adhesive (glues).
Chickens treated by paintbrushing with glue distillate (used in shoe industries), hydrocarbon mixture and TOCP in hexane, developed paralysis (4/5); in these, we have demonstrated a diffuse degeneration of the myelinic sheath of the peripheral and central neurites. Besides TOCP, cyclohexane (because of its higher concentration in the glue distillate and in the hydrocarbon mixture) may be indicated as responsible for occupational neuropathy.
D000269:Adhesives / Q000009:adverse effects*; D000818:Animals; D002645:Chickens; D003408:Cresols / Q000009:adverse effects; D006586:Hexanes / Q000009:adverse effects; D009422:Nervous System Diseases / Q000139:chemically induced* / Q000473:pathology; D009784:Occupational Diseases / Q000139:chemically induced / Q000473:pathology; D009943:Organophosphorus Compounds / Q000009:adverse effects; D010243:Paralysis / Q000139:chemically induced / Q000473:pathology; D012775:Shoes; D012997:Solvents / Q000009:adverse effects
D000269:Adhesives; D003408:Cresols; D006586:Hexanes; D009943:Organophosphorus Compounds; D012997:Solvents