Bioavailability of erythromycin ethylsuccinate in pediatric patients.
A parallel treatment group bioavailability study was undertaken in children 6 to 65 months of age, comparing fasting and nonfasting erythromycin serum levels after a single oral dose of erythromycin ethylsuccinate granules. Results demonstrated significantly higher levels in the nonfasting than in the fasting state, while fasting state levels were comparable to those found in studies of adult subjects receiving recommended doses of the same compound.
D001424:Bacterial Infections / Q000188:drug therapy; D001682:Biological Availability; D002675:Child, Preschool; D004917:Erythromycin / Q000031:analogs & derivatives* / Q000097:blood / Q000627:therapeutic use; D005215:Fasting; D006801:Humans; D007223:Infant
D004917:Erythromycin