[Interaction of paramagnetic probes with submitochondrial particle membranes].
Redox-transformations of some paramagnetic probes differing in chemical structure have been studied during their interaction with the membranes of submitochondrial particles. Dependence of the probe restoration kinetics on the conditions of functioning of the electron-transport chain, presence of oxygen, respiration substrate, electron transport inhibitors (antimycin, alpha tenoiltriftoracetate, potassium cyanide) in the reaction mixture is shown. Water-soluble as well as strongly hydrophobic spin probes are restored when the respiration substrate (succinate) is present; they interact with the lipid-soluble carrier ubiquinone.
D000968:Antimycin A / Q000494:pharmacology; D003486:Cyanides / Q000494:pharmacology; D003497:Cyclic N-Oxides; D004579:Electron Transport / Q000187:drug effects; D008566:Membranes; D010084:Oxidation-Reduction; D010100:Oxygen; D013113:Spin Labels; D013347:Subcellular Fractions; D013804:Thenoyltrifluoroacetone / Q000494:pharmacology
D003486:Cyanides; D003497:Cyclic N-Oxides; D013113:Spin Labels; D013804:Thenoyltrifluoroacetone; D000968:Antimycin A; D010100:Oxygen
Issledovanie vzaimodeĭstviia paramagnitnykh zondov s membranoĭ submitokhondrial'nykh chastits.