Similarity of clinical and laboratory results obtained with microporous teflon membrane oxygenator and bubble-film hybrid oxygenator.
For 80 elective clinical cardiopulmonary bypasses we alternately used either a commercial microporous Teflon membrane oxygenator or a commercial hybrid bubble-film oxygenator. Setup time was a little longer with the membrane unit (20 minutes), but priming volume (2,250 ml) was the same. No problems were encountered with the hybrid oxygenator. However, despite our monitoring of additional variables, including shim and inlet pressure and recirculation flow, gas exchange abnormalities were encountered in 5 patients on whom the membrane oxygenator was used; in 4 of these cases the abnormalities were encountered prior to our recognition of the potential for occasional internal shunting with this device. There were no hospital deaths. When the two groups, matched except for oxygenator selection, were compared, there were no significant differences clinically or hematologically. For cardiopulmonary bypass of 2 hours or less, both oxygenators studied are definite improvements over previous silicone membrane and high-gas-flow bubble oxygenators. However, lower cost and reduced complexity favor the hybrid oxygenator.
D001786:Blood Glucose / Q000032:analysis; D001792:Blood Platelets; D001803:Blood Transfusion; D001806:Blood Urea Nitrogen; D002315:Cardiopulmonary Bypass; D004322:Drainage; D005340:Fibrinogen / Q000032:analysis; D006400:Hematocrit; D006801:Humans; D010106:Oxygenators; D010107:Oxygenators, Membrane; D011517:Prothrombin Time; D013909:Thorax
D001786:Blood Glucose; D005340:Fibrinogen