Hydronephrosis, renal agenesis, and associated genitourinary anomalies in ACI rats.
The ACI rat provides a congenital mammalian model for the spontaneously occurring defects of renal agenesis and hydronephrosis. These anomalies appear to be part of a spectrum of abnormalities caused by a mesonephric duct defect. These same anomalies also exist in man probably more commonly than previously appreciated.
D000015:Abnormalities, Multiple / Q000235:genetics* / Q000473:pathology; D000818:Animals; D000831:Animals, Newborn; D005260:Female; D006869:Hydronephrosis / Q000150:complications / Q000235:genetics* / Q000473:pathology; D007668:Kidney / Q000002:abnormalities* / Q000473:pathology; D008297:Male; D011247:Pregnancy; D051381:Rats; D011912:Rats, Inbred ACI / Q000196:embryology / Q000235:genetics*; D011919:Rats, Inbred Strains / Q000235:genetics*; D014564:Urogenital Abnormalities; D014566:Urogenital System / Q000473:pathology