[Energetic swelling and lysis of mitochondria].
B1 avitaminosis presents a typical example of energetic mitochondrial degeneration. The alterations--swelling and lysis of mitochondria--are accompanied by dilatation with formation of megamitochondria, by appearance of blebs and tearings of the mitochondrial membranes, by progressive fading of the matrix, by swelling of the mitochondrial membranes with lysis of the cristae advancing from centre towards periphery, by vacuolar transformation of the cell and by development of onionoid bodies (corpora cepiformia).
D000818:Animals; D008928:Mitochondria / Q000648:ultrastructure*; D008933:Mitochondrial Swelling; D010179:Pancreas / Q000648:ultrastructure; D051381:Rats; D013832:Thiamine Deficiency / Q000473:pathology*
Energetische Verquellung und Lyse der Mitochondrien.