The attenuation of prostaglandin-induced luteolysis in decidual tissue-bearing pseudopregnant rats.
Decidual tissue (DT)-bearing pseudopregnancy (PSP) rats, in contrast to hysterectomized PSP rats, were resistant to a luteolytic regimen of either PGF2alpha or PGE2 when examined for the duration of PSP diestrus. The PG treatments, however, caused a marked fall in the serum progesterone levels on days 10 and 12, although the levels in DT-bearing rats on day 10 were significantly higher than in the hysterectomized rats.
D000818:Animals; D002369:Castration; D003338:Corpus Luteum / Q000187:drug effects*; D003656:Decidua / Q000187:drug effects*; D005260:Female; D011374:Progesterone / Q000097:blood; D011453:Prostaglandins / Q000494:pharmacology*; D011458:Prostaglandins E / Q000494:pharmacology; D011460:Prostaglandins F / Q000494:pharmacology; D011555:Pseudopregnancy; D051381:Rats
D011453:Prostaglandins; D011458:Prostaglandins E; D011460:Prostaglandins F; D011374:Progesterone