Haemoglobin switching during development in normal and hypophysectomised fetal sheep.
Haemoglobin synthesis has been studied in fetal sheep. The switch from gamma to beta chain synthesis occurs rapidly between 130 and 150 days. Fetal hypophysectomy delays the rate of switching but the timing of the onset of the switch is not under pituitary control.
D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D005319:Fetal Hemoglobin / Q000096:biosynthesis*; D006441:Hemoglobin A / Q000096:biosynthesis; D006453:Hemoglobinopathies / Q000503:physiopathology; D006454:Hemoglobins / Q000096:biosynthesis*; D007016:Hypophysectomy; D011247:Pregnancy; D012756:Sheep
D006454:Hemoglobins; D006441:Hemoglobin A; D005319:Fetal Hemoglobin