[Evaluation of the vegetable oil taken up into the duodenum as a factor in pancreozymin liberation in healthy persons and in digestive organ diseases].
Investigations carried out in 14 healthy volunteers, 29 patients with chronic pancreatitis and 15 patients with chronic hepatitis showed that infusion into the duodenum of an optimally tolerable quantity (25 ml) of vegetable oil makes for a release of an amount of pancreozymin, which, by the criterion for stimulating secretion of pancreatic amylase, is equivalent to 0.5 Un/kg of pure preparation of pancreozymin and, as to the degree of stimulating the secretion of lipase and trypsin, it exceeds the effect of 0.5 Un/kg, but is less than that of 1.5 Un/kg of pure pancreozymin. These data should be taken into account in evaluating the ability of some alimentary fats to stimulate the release of endogenous pancreozymin.
D002766:Cholecystokinin / Q000378:metabolism*; D002908:Chronic Disease; D004386:Duodenum / Q000378:metabolism*; D004789:Enzyme Activation / Q000187:drug effects; D005767:Gastrointestinal Diseases / Q000378:metabolism*; D006262:Health; D006505:Hepatitis / Q000378:metabolism; D006801:Humans; D009821:Oils / Q000378:metabolism*; D010195:Pancreatitis / Q000378:metabolism; D010945:Plants, Edible; D012008:Recurrence
D009821:Oils; D002766:Cholecystokinin
Otsenka postupivshego v dvenadtsatiperstnuiu kishku rastitel'nogo masla kak faktora osvobozhdeniia pankreozimina u zdorovykh liudeĭ i pri bolezniakh organov pishchevareniia.