Isolation of mutants with altered metabolic control of the NAH plasmid-encoded catechol meta-cleavage pathway.
Two types of mutants which displayed altered regulation of the NAH catabolic plasmid-encoded catechol meta-cleavage pathway were isolated in Pseudomonas putida. Altered metabolic control was indicated by assay of catechol 2,3-dioxygenase. In one type of mutant the catechol 2,3-dioxygenase was synthesized constitutively. In the other type the range of carbon sources which induce the catechol 2,3-dioxygenase was increased.
D002396:Catechols / Q000378:metabolism*; D004790:Enzyme Induction; D009154:Mutation; D010105:Oxygenases / Q000096:biosynthesis; D010957:Plasmids; D011549:Pseudomonas / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*
D002396:Catechols; D010105:Oxygenases