Mitogenicity of cell wall fractions of Micropolyspora faeni.
Cell wall fractions of Micropolyspora faeni, a causative agent of hypersensitivity pneumonitis, have been shown to possess non-specific mitogenic activity for guinea pig, rabbit and human lymphocytes. This activity was unrelated to endotoxin and may not be associated with peptidoglycan. This lymphocyte proliferation stimulus may play a role in the adjuvant properties of this organism and in the etiology of hypersensitivity lung disease.
D000818:Animals; D002473:Cell Wall; D006168:Guinea Pigs; D008033:Limulus Test; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D008848:Micromonosporaceae / Q000276:immunology*; D008934:Mitogens; D009112:Muramic Acids; D011817:Rabbits; D013154:Spleen / Q000166:cytology
D008934:Mitogens; D009112:Muramic Acids