Treatment of sudden deafness with sodium salts of triiodobenzoic acid derivatives.
Twenty-two patients with a complaint of sudden deafness were treated with one of the other of two radiopaque contrast media, 9 received daily doses of sodium iothalamate, and 13 were treated similarly with methylglucamine and sodium iodamide. Four of the first group and eight of the second demonstrated either an effective partial or a complete recovery of hearing function. Those failing to respond were generally classified completely deaf at admission and report nausea, vomiting, or vertigo at onset of sudden deafness. Treatment with sodium salts of triiodobenzoic acid derivatives, i.e., sodium iothalamate and methylglucamine and sodium iodamide, is judged to be effective in selected cases of sudden deafness.
D000293:Adolescent; D000328:Adult; D003287:Contrast Media / Q000627:therapeutic use*; D003638:Deafness / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007451:Iodamide / Q000627:therapeutic use; D007483:Iothalamic Acid / Q000627:therapeutic use; D008297:Male; D008536:Meglumine / Q000627:therapeutic use; D008875:Middle Aged
D003287:Contrast Media; D007483:Iothalamic Acid; D007451:Iodamide; D008536:Meglumine