[Hemolytic and aplastic crisis as a cause of anemia in congenital hemolytic diseases (spherocytosis)].
The author shows 45 patients suffering from congenital spherocytosis, tested by Cr-51. The author in 8 cases has found decreased T1/2 without anemia and splenomegaly, and in 13 cases with reduced T1/2, with anemia and without splenomegaly, and in 24 cases remarkably reduced T1/2, with anemia and congestive splenomegaly (proved increased blood plasma volume and increased index spleen: heart first day of testing). The author emphasizes the importance of "aplastic crisis" which is expressed in infection or other disturbances, as the cause of anemia, as well as the importance of "hemolytic crisis" which is expressed in increased splenic activity, also as the cause of anemia in congenital spherocytosis.
D000293:Adolescent; D000740:Anemia / Q000150:complications; D002648:Child; D004911:Erythrocyte Volume; D006207:Half-Life; D006801:Humans; D010953:Plasma Volume; D013103:Spherocytosis, Hereditary / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D013154:Spleen / Q000503:physiopathology; D013156:Splenectomy; D013163:Splenomegaly / Q000150:complications
Hemolizna i aplazna kriza kao uzroci anemije u urodenim hemoliznim bolestima (sverocitozi).