Isochromosome for the long arm of the Y in an infertile male.
A 37-year-old man investigated for infertility had bilateral atrophic testes. Cytogenetic investigations revealed a chromosome complement of 45,XO/46,Xi(Yq)/46,XY. Mechanisms for the origin of the i(Yq) are considered, and the relation of his chromosome constitution to his infertility and hypogonadism are discussed.
D000328:Adult; D001284:Atrophy; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D008297:Male; D012729:Sex Chromosome Aberrations / Q000150:complications*; D012730:Sex Chromosomes; D013737:Testis / Q000473:pathology; D014998:Y Chromosome