Immunoglobulins and secretory component in the external secretions of foals with combined immunodeficiency.
Nasal washings and tears were collected from seven Arabian foals with combined immunodeficiency and nine normal foals. The major immunoglobulin in the external secretions of normal foals over 2 months of age was secretory immunoglobulin A, whereas foals with combined immunodeficiency lacked this immunoglobulin. The external secretions of both normal and immunodeficient foals contained free secretory component at birth.
D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D006734:Horse Diseases / Q000276:immunology*; D006736:Horses; D007070:Immunoglobulin A / Q000096:biosynthesis*; D007128:Immunoglobulin Fragments / Q000096:biosynthesis*; D007153:Immunologic Deficiency Syndromes / Q000276:immunology / Q000662:veterinary*; D009297:Nasal Mucosa / Q000378:metabolism*; D012635:Secretory Component / Q000096:biosynthesis*; D013666:Tears / Q000276:immunology*
D007070:Immunoglobulin A; D007128:Immunoglobulin Fragments; D012635:Secretory Component