Immunopathology of rheumatoid arthritis.
The central place of immunologic aberrations in the pathology of rheumatoid arthritis is now well established. It is the nature and interactions of these aberrations that still remain to be elucidated. Among the many puzzles being studied are the uniquely self-perpetuating nature of rheumatoid arthritis immune complexes and the role of complement and the prostaglandins in joint damage and pain.
D000936:Antigen-Antibody Complex; D001172:Arthritis, Rheumatoid / Q000209:etiology / Q000276:immunology* / Q000473:pathology; D003165:Complement System Proteins / Q000502:physiology; D006801:Humans; D011453:Prostaglandins / Q000502:physiology; D012217:Rheumatoid Factor / Q000032:analysis; D012218:Rheumatoid Nodule / Q000473:pathology; D013583:Synovial Membrane / Q000276:immunology
D000936:Antigen-Antibody Complex; D011453:Prostaglandins; D003165:Complement System Proteins; D012217:Rheumatoid Factor