Bovine vibriosis vaccination: immunity conferred by a single biotype.
An adjuvant vaccine was prepared from an Australian isolate of Campy-lobacter fetus subsp fetus biotype intermedius and injected into 23 virgin Guernsey heifers. Ten nonvaccinated animals served as controls. When challenged by the intravaginal route with a culture of either the homologous strain or biotype venerealis, weekly swabs from the anterior vagina continued to yield either biotype in 8 of 10 nonvaccinates at 6 weeks as compared with 3 of 23 vaccinates. Serology in vaccinated heifers and rabbits showed that the vaccine produced high titres of antibody against both homologous and heterologous strains.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D001428:Bacterial Vaccines; D002167:Campylobacter / Q000276:immunology*; D002169:Campylobacter Infections / Q000276:immunology / Q000662:veterinary*; D002168:Campylobacter fetus / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D005260:Female; D007109:Immunity; D014611:Vaccination / Q000662:veterinary*
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines