[The potentiation of stimulated gastric juice secretion by prednisolone].
In 5 series of dogs the acute effect of a high dose of prednisolone (40 mg/kg i.v.) on Histalog stimulated gastric secretion (5 mg/kg s.c.) was tested. There was no effect of prednisolone alone. The combination of Histalog and prednisolone showed a potentiation of Histalog stimulation in high range. The effect was not seen when truncal vagotomy was performed before stimulation. It is possible that there is a cholinergic reaction or an interaction in the metabolism of histamine.
D000818:Animals; D001625:Betazole / Q000494:pharmacology; D004285:Dogs; D005750:Gastric Juice / Q000187:drug effects*; D008297:Male; D011239:Prednisolone / Q000494:pharmacology*; D014628:Vagotomy
D001625:Betazole; D011239:Prednisolone
Untersuchungen zur Potenzierung der stimulierten Magensäure-Sekretion durch Prednisolon.