Dexamethasone-induced neutrophilia. Negative correlation with increased plasma adrenaline concentrations.
Maximal increments in adrenaline and dexamethasone (DXM) plasma concentrations were observed c15 (T50 40 min) and 30 (T50 210-240 min) minutes after an i.v. DXM dose (6 mg/m2 BSA) in man. There appears, however, to be no direct interaction between these agents in the development of induced neutrophilia, which occurs c240 min postinjection.
D000328:Adult; D003907:Dexamethasone / Q000009:adverse effects*; D004837:Epinephrine / Q000097:blood*; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000187:drug effects*; D013997:Time Factors
D003907:Dexamethasone; D004837:Epinephrine