[Genetic determination of the immune response of mice to cells of various histological types].
The intensity of the immune response of cells in mice to strong transplantation antigens of the H-2 complex can depend on the histological type of cells taken for immunization. Splenic cells of C3H mice immunized the cells of BALB/c line better that cells of the non-lymphoid origin taken from the same donor. A reverse situation was observed in case of immunization by the same cells of the lines C57Bl/6 and A/He. It was shown by the analysis of the lines of the first generation derived from the crosses between the 3 lines studied and also by the analysis of these characters in mice born from the backcross, that these characters do not exhibit a simple Mendelian segregation.
D000818:Animals; D000937:Antigen-Antibody Reactions; D003433:Crosses, Genetic; D003602:Cytotoxicity, Immunologic; D005838:Genotype; D007109:Immunity; D007111:Immunity, Cellular; D007114:Immunization; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D008805:Mice, Inbred A; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains / Q000235:genetics* / Q000276:immunology; D013154:Spleen / Q000166:cytology; D014181:Transplantation Immunology
Geneticheskaia determinirovannost' immunnogo otveta mysheĭ na kletki raznogo gistologicheskogo tipa.