Cactecholamines and the oedematous reaction to oestradiol in the rat uterus.
The effect of catecholamines on the 4 h oedematous reaction to estradiol in the immature rat uterus was investigated. Isoprenaline was found to augment the reaction to suboptimal doses of estradiol (0.25--0.5 microgram/kg. This effect was reversed by d,l-propranolol. Adrenaline and noradrenaline were found to inhibit the reaction to oestradiol 2 microgram/kg. The effect of adrenaline was reversed by phenotalmine.
D000818:Animals; D002395:Catecholamines / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004487:Edema / Q000139:chemically induced*; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D014599:Uterus / Q000187:drug effects*
D002395:Catecholamines; D004958:Estradiol