Human liver alcohol dehydrogenase isoenzyme variations. Improved separation methods using prolonged high voltage starch-gel electrophoresis and isoelectric focusing.
Human liver alcohol dehydrogenase isozyme patterns were studied using prolonged high voltage starch-gel electrophoresis and gel-slab isoelectric focusing. Homo- and heterodimers of ADH2 locus were easily distinguished from each other. The gene frequencies of ADH2 2 and ADH2 3 in 46 random liver samples from Germany were found to be 0.044 and 0.424 respectively.
D000429:Alcohol Oxidoreductases / Q000235:genetics* / Q000302:isolation & purification; D005787:Gene Frequency; D005860:Germany, West; D006801:Humans; D007527:Isoenzymes / Q000235:genetics* / Q000302:isolation & purification; D008099:Liver / Q000201:enzymology*; D008722:Methods
D007527:Isoenzymes; D000429:Alcohol Oxidoreductases