An in vitro model of liver injury using paracetamol treatment of liver slices and prevention of injury by some antioxidants.
D000082:Acetaminophen / Q000009:adverse effects* / Q000037:antagonists & inhibitors; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000378:metabolism / Q000517:prevention & control; D003640:Dealkylation; D005978:Glutathione / Q000378:metabolism; D066298:In Vitro Techniques; D007521:Isocitrate Dehydrogenase / Q000378:metabolism; D008297:Male; D011188:Potassium / Q000378:metabolism; D051381:Rats
D000975:Antioxidants; D000082:Acetaminophen; D007521:Isocitrate Dehydrogenase; D005978:Glutathione; D011188:Potassium