The influence of imipramine on the circulatory system and some other parameters of arterial hypertension.
Imipramine in doses of 0.35-0.45 mg/kg body weight usually induces a drop in arterial blood pressure; the drop is statistically significant in patients with essential hypertension. In these patients, a significant increase in excretion of catecholamines in urine was observed when compared with a control group. In both groups no changes in heart action were found.
D000328:Adult; D002395:Catecholamines / Q000652:urine; D004804:Eosinophils / Q000187:drug effects; D005654:Fundus Oculi / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007099:Imipramine / Q000627:therapeutic use*; D008875:Middle Aged
D002395:Catecholamines; D007099:Imipramine