[Molecular mechanisms of receptor. II. Identification of the conformational transition of rhodopsin responsible for the leading edge of the photoresponse of artificial lipid membranes modified by fragments of the outer segment of rods].
Kinetic parameters of photoinduced permeability increase of artificial lipid membranes, modified by ROS fragments (tau20 degrees C = 20 mesec Ea = 33 +/- 2 kcal/mole) coincides with appropriate parameters of photoinduced protein fluorescence intensity decrease and ROS fragments absorption spectra change (metarhodopsin I leads leads to metarhodopsin II transition). Hydroxylamine accelerates this process, its rate is proportional to hydroxylamine at concentrations lower than 0.6 M.
D002462:Cell Membrane / Q000528:radiation effects; D006898:Hydroxylamines; D007700:Kinetics; D008027:Light; D008563:Membrane Lipids / Q000528:radiation effects; D008567:Membranes, Artificial; D008968:Molecular Conformation / Q000528:radiation effects; D010786:Photoreceptor Cells / Q000502:physiology* / Q000528:radiation effects* / Q000648:ultrastructure; D012168:Retinal Pigments / Q000528:radiation effects*; D012243:Rhodopsin / Q000528:radiation effects*; D013050:Spectrometry, Fluorescence; D013696:Temperature; D013816:Thermodynamics
D006898:Hydroxylamines; D008563:Membrane Lipids; D008567:Membranes, Artificial; D012168:Retinal Pigments; D012243:Rhodopsin
Molekuliarnye mekhanizmy gerneratsii retseptornogo potentsiala fotoretseptorom. II. Identifikatsiia konformatsionnogo perekhoda rodopsina, otvetstvennogo za perednii front fotootveta iskusstvennoĭ lipidnoĭ membrany, modifitsirovannoĭ fragmentami naruzhnogo segmenta palochki.