Malignant astrocytoma following radiotherapy of a craniopharyngoima. Case report.
A 9-year-old schoolgirl received 6007 rads to the suprasellar region for craniopharyngioma. Five years later, a malignant astrocytoma developed in the right temporal lobe. We cite clinical and experimental evidence to support our suspicion that the glioma may have been induced by radiation.
D001254:Astrocytoma / Q000209:etiology*; D001932:Brain Neoplasms / Q000209:etiology*; D002648:Child; D003397:Craniopharyngioma / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D009381:Neoplasms, Radiation-Induced; D010911:Pituitary Neoplasms / Q000532:radiotherapy*; D011878:Radiotherapy / Q000009:adverse effects*; D013702:Temporal Lobe