Trisomy 18 syndrome with an unusual karyotype: possible double isochromosome.
Chromosome analysis of an infant with characteristic features of trisomy 18 is presented. The chromosome complement contained a modal count of 47 but there was only one No. 18. In addition, there were two metacentric chromosomes of different sizes. The two metacentric chromosomes were identified by G- and C-banding to be possible isochromosomes of the long and short arms of a No. 18 chromosome.
D001399:Azure Stains; D002875:Chromosomes / Q000648:ultrastructure; D002877:Chromosomes, Human; D002902:Chromosomes, Human, 16-18; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007621:Karyotyping; D014314:Trisomy
D001399:Azure Stains