Effects of maternal dodecanoic or lauric acid (C12:0) feeding on milk fatty acid secretion and lipogenesis in the suckling rat.
Lauric acid feeding induced large alterations in mammary gland fatty acid secretion. It was highly incorported in milk triglycerides, suggesting that mammary gland was not able to efficiently regulate the qualitative aspects of medium-chain fatty acid secretion. These modifications in milk fatty acid secretion did not alter pup growth, lipogenesis balance or the classic parameters of the pup liver during the suckling period. Nevertheless, maternal lauric acid feeding induced important alterations in the qualitative aspects of pup lipogenesis before weaning.
D000821:Animal Feed; D000818:Animals; D004041:Dietary Fats; D005227:Fatty Acids / Q000378:metabolism*; D005260:Female; D007774:Lactation; D007850:Lauric Acids; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D008321:Mammary Glands, Animal / Q000378:metabolism; D008892:Milk / Q000378:metabolism*; D051381:Rats; D014886:Weaning
D004041:Dietary Fats; D005227:Fatty Acids; D007850:Lauric Acids