[Activation of hypersynchronous discharges in the visual cortex using corazole].
A study was made of the firing (extracellular records) of the rabbit visual cortex cells during hypersynchronous rhythmics of the wave-peak type, provoked by intravenous injection of subconvulsive doses of corasol. The analysis suggests that the wave-peak discharge results from synchronous alternation of depolarization potentials and long periods of postsynaptic inhibition in most of the cortical elements. In the course of involvement of new elements in the reaction, there is an increase in the probability of appearance of populations with a different frequency of discharge; this is one of the causes of discontinuation of the paroxysmal rhythm following small doses of corasol.
D000818:Animals; D002682:Chinchilla; D008564:Membrane Potentials / Q000187:drug effects; D009433:Neural Inhibition / Q000187:drug effects; D010433:Pentylenetetrazole / Q000494:pharmacology*; D011817:Rabbits; D013570:Synaptic Membranes / Q000187:drug effects; D014793:Visual Cortex / Q000187:drug effects*
D010433:Pentylenetetrazole
Ob aktivatsii gipersinkhronnykh razriadov v zritel'noĭ kore s pomosh'iu korazola.