A cancer-associated, fast, homoarginine-sensitive electrophoretic form of serum alkaline phosphatase.
Serum from patients with a variety of cancers often (p = 70%) contains a characteristic electrophoretic form of alkaline phosphatase detectable by cellulose polyacetate electrophoresis. The lower prevalence of this electrophoretic form in presumably healthy individuals (p = 7%) and noncancer hospitalized patients (p = 30%) suggests that it may be useful as a diagnostic or monitory marker.
D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood* / Q000302:isolation & purification; D001120:Arginine / Q000031:analogs & derivatives*; D004588:Electrophoresis, Cellulose Acetate; D005260:Female; D006709:Homoarginine / Q000494:pharmacology*; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D008297:Male; D009369:Neoplasms / Q000201:enzymology*; D012075:Remission, Spontaneous
D007527:Isoenzymes; D006709:Homoarginine; D001120:Arginine; D000469:Alkaline Phosphatase