Myotonic muscular dystrophy: altered calcium transport in erythrocytes.
Erythrocytes from patients with myotonic muscular dystrophy accumulate calcium at a significantly higher rate than normals do. This increased rate of net accumulation appears related to an enhanced permeability of the membrane to calcium, rather than to an impairment in its active outward transport.
D001692:Biological Transport / Q000187:drug effects; D002118:Calcium / Q000097:blood* / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D004910:Erythrocyte Membrane / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D009136:Muscular Dystrophies / Q000097:blood* / Q000378:metabolism; D011803:Quinine / Q000494:pharmacology
D011803:Quinine; D002118:Calcium