14-3-2 protein in rat brain.
The distribution of the 14-3-2 protein in rat brain was investigated by immuno-electron microscopy using antiserum to the protein conjugated with peroxidase. 14-3-2 was demonstrated in the nuclear membrane, the endoplasmic reticular membranes and in the plasma membrane of nerve cells. The protein was also localized to the presynaptic densities and to the pre- and postsynaptic membranes. It could not be demonstrated in the membranes of the Golgi complex, inner membrane of mitochondria or in the nucleoplasm of neurons. No 14-3-2 protein was found in astrocytes, oligodendrocytes or in non-neuroectodermal tissue elements.
D000818:Animals; D001923:Brain Chemistry; D002462:Cell Membrane / Q000032:analysis; D004721:Endoplasmic Reticulum / Q000032:analysis; D008297:Male; D009419:Nerve Tissue Proteins / Q000032:analysis*; D009474:Neurons / Q000032:analysis; D009685:Nuclear Envelope / Q000032:analysis; D051381:Rats; D013570:Synaptic Membranes / Q000032:analysis
D009419:Nerve Tissue Proteins