Agglutination of leukemic cells and daunomycin entrapped erythrocytes with lectin in vitro and in vivo.
Wheat germ agglutinin (WGA) agglutinated the L1210 leukemic cells and daunomycin entrapped erythrocytes in vitro. Comparing with control preparations, the greatest increase in survival was obtained in vivo when the daunomycin entrapped erythrocytes and WGA were given to BDF1 mice bearing L1210 cells.
D000818:Animals; D003630:Daunorubicin / Q000008:administration & dosage / Q000627:therapeutic use; D004910:Erythrocyte Membrane / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology*; D066298:In Vitro Techniques; D037102:Lectins / Q000494:pharmacology*; D007939:Leukemia L1210 / Q000276:immunology*; D051379:Mice; D037121:Plant Lectins; D014908:Triticum
D037102:Lectins; D037121:Plant Lectins; D003630:Daunorubicin