Intracardiac heterotopia--mesenchymal and endodermal.
A case is reported of an intracardiac 'epithelial heterotopia' with a predominant mesenchymal component. This is thought to have resulted from the differentiation of aberrant primitive cell(s) displaced into the heart during its development. Though microscopically resembling a myxoma, this lesion is clearly distinguished by the presence of glandular structures. The myxoid component exhibited a startling invasiveness which resulted in occlusion of the superior vena cava, causing symptoms very early in life and death at the age of 6 months.
D002828:Choristoma / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D004707:Endoderm / Q000473:pathology; D006338:Heart Neoplasms / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D009232:Myxoma / Q000175:diagnosis; D009361:Neoplasm Invasiveness; D014683:Vena Cava, Superior / Q000473:pathology