Histologic findings in the temporal bone in trisomy D (D/D translocation).
The temporal bones of an infant in whom the diagnosis of unblaanced trisomy D (D/D translocation) had been made by chromosomal analysis during life were studied histologically. Most of the findings resembled those that have been described by others in trisomy D (13-15) syndrome. A previously unreported abnoramlity was substrial edema displacing the stria vascularis. The importance of this finding remains to be defined by further study.
D000015:Abnormalities, Multiple / Q000473:pathology; D002901:Chromosomes, Human, 13-15; D004423:Ear / Q000002:abnormalities* / Q000473:pathology; D004427:Ear Diseases / Q000473:pathology; D007758:Ear, Inner / Q000473:pathology; D004432:Ear, Middle / Q000473:pathology; D004487:Edema / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000473:pathology; D008297:Male; D013701:Temporal Bone / Q000473:pathology*; D014178:Translocation, Genetic; D014314:Trisomy