Rose Bengal plate agglutination and counterimmunoelectrophoresis tests on spinal fluid in the diagnosis of Brucella meningitis.
Rose Bengal and counterimmunoelectrophoresis, two tests that detect antibodies against different structural antigens, when carried out on spinal fluid permitted rapid diagnosis of human Brucella meningitis. The Rose Bengal test was positive in five out of five patients studied, and counterimmunoelectrophoresis was positive in all but one. The Brucella meningitis was characterized by an increase of immunoglobulin G in the cerebrospinal fluid.
D000372:Agglutination Tests; D000907:Antibodies, Bacterial / Q000134:cerebrospinal fluid; D000942:Antigens, Bacterial; D002002:Brucella / Q000276:immunology; D002006:Brucellosis / Q000175:diagnosis*; D002555:Cerebrospinal Fluid / Q000276:immunology*; D003378:Counterimmunoelectrophoresis; D003937:Diagnosis, Differential; D006801:Humans; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D008581:Meningitis / Q000175:diagnosis*; D012395:Rose Bengal
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D007074:Immunoglobulin G; D012395:Rose Bengal