Serum ornithine carbamoyltransferase (OCT) in rats poisoned with lanthanum, cerium and praseodymium.
Serum ornithine carbamoyltransferase (OCT) in rats poisoned with lanthanum, cerium and praseodymium. Acta Physiol. Pol., 1977, 28 (6): 589-594. The serum ornithine carbamoyltransferase in relation to doses of lanthanum, cerium and praseodymium, administered intravenously as chlorides, was investigated. A directly proportional relationship was found between the doses of these compounds and the serum enzyme level in rats. The lowest doses at which a rise in the serum OCT level occured were determined. They were: lanthanum - 0.75 mg/kg of body weight, cerium - 1.5 mg/kg, and praseodymium - 3 mh/kg. A decreasing toxicity of these elements with increasing value of atomic number was observed.
D000818:Animals; D002563:Cerium / Q000506:poisoning; D005260:Female; D007811:Lanthanum / Q000506:poisoning; D008674:Metals, Rare Earth / Q000506:poisoning*; D009954:Ornithine Carbamoyltransferase / Q000097:blood*; D011221:Praseodymium / Q000506:poisoning; D051381:Rats
D008674:Metals, Rare Earth; D002563:Cerium; D007811:Lanthanum; D009954:Ornithine Carbamoyltransferase; D011221:Praseodymium