[Bladder carcinoma associated with long-term treatment with cyclophosphamide for multiple myeloma (author's transl)].
A report is presented of a female patient who developed an extensive bladder carcinoma with severe hemorrhaging after many years of treatment with cyclophosphamide for multiple myeloma. The severe hemorrhage could only be controlled by drainage of the urine. The possible causes of the development of a second neoplasia, particularly of urinary bladder carcinoma following long-term therapy with cyclophosphamide, are discussed.
D000368:Aged; D003520:Cyclophosphamide / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced; D006801:Humans; D009101:Multiple Myeloma / Q000188:drug therapy; D001745:Urinary Bladder Diseases / Q000139:chemically induced; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced*
D003520:Cyclophosphamide
Blasenkarzinom bei langjähriger Behandlung mit Cyclophosphamid wegen multiplem Myelom.