[Experimental study of a gentamycin ointment].
Technology of 0.1 per cent gentamicin ointment production was developed. The ointment base consisted of vaseline and parafin (95:5). Pharmacokinetics and innocuousness of the gentamicin ointment were studied. It was shown that the ointment provided gentamicin diffusion through the skin utegument during a long period of time. Histological studies showed no local irritating effect of the ointment on the skin in its local use.
D000287:Administration, Topical; D000818:Animals; D004353:Drug Evaluation, Preclinical; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use*; D007700:Kinetics; D008297:Male; D009824:Ointments; D011817:Rabbits; D012867:Skin / Q000187:drug effects; D012869:Skin Absorption / Q000187:drug effects; D014783:Viscosity
D005839:Gentamicins; D009824:Ointments
Eksperimental'noe izuchenie gentamitsinovoĭ mazi.