High-voltage electron microscopy of adrenal medulla: direct connections between mitochondria and catecholamine-storage vesicles.
A high-voltage electron microscopic study of adrenal medullary cells from hypoglycemia-stressed rats revealed the existence of tubular channels which create a luminal continuity between the mitochondrial compartment and the catecholamine-storage vesicles. It is suggested that these channels allow for the transfer of materials such as high-energy nucleotides between the mitochondria and the catecholamine-storage vesicles without an intervening membrane.
D000313:Adrenal Medulla / Q000378:metabolism / Q000473:pathology / Q000648:ultrastructure*; D000818:Animals; D002395:Catecholamines / Q000378:metabolism*; D007003:Hypoglycemia / Q000473:pathology; D008870:Microtubules; D008928:Mitochondria / Q000648:ultrastructure*; D051381:Rats
D002395:Catecholamines