Triiodothyronine-secreting (toxic) adenoma of the thyroid gland: light and electron microscopic characteristics.
A patient with thyrotoxicosis due to a triiodothyronine (T3)-secreting autonomous adenoma is described. The histmorphology of the neoplasms was similar to other neoplasms previously reported. Ultrastructural features of the adenoma are compatible with a very actively secreting follicular cell and are best compared with the ultrastructure of a diffuse toxic goiter. Distinctive features that separate toxic adenomas from various thyroid carcinomas and normal thyroid parenchyma are discussed.
D000236:Adenoma / Q000150:complications / Q000378:metabolism / Q000648:ultrastructure*; D000328:Adult; D002277:Carcinoma / Q000648:ultrastructure; D002291:Carcinoma, Papillary / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia; D006980:Hyperthyroidism / Q000209:etiology; D008854:Microscopy, Electron; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D013964:Thyroid Neoplasms / Q000150:complications / Q000378:metabolism / Q000648:ultrastructure*; D014284:Triiodothyronine / Q000378:metabolism*
D014284:Triiodothyronine