A study on the evaluation of local shati starch as a substitute of polysaccharides used in the preparation of capsules and tablets of antibiotics.
Local shati starch was extracted, purified and used as an excipient for the preparation of capsules and tablets of oxytetracycline and chloramphenicol. The weight variation test, disintegration time and hardness test of these dosage forms were done and compared with the conventional maize starch containing tables and capsules of the antibiotics. The results in respect of their potency test were found to conform to official pharmacopoeias (B.P. and U.S.P). Stability study for over one year of both varieties of tablets and capsules revealed that they retained their potencies equally well.
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002214:Capsules; D004339:Drug Compounding; D005079:Excipients; D014677:Pharmaceutical Vehicles; D010944:Plants; D011134:Polysaccharides; D013213:Starch; D013607:Tablets
D000900:Anti-Bacterial Agents; D002214:Capsules; D005079:Excipients; D014677:Pharmaceutical Vehicles; D011134:Polysaccharides; D013607:Tablets; D013213:Starch