The isolation and characterization of narasin, a new polyether antibiotic.
Narasin is a new polyether antibiotic produced by a strain of Streptomyces aureofaciens. It is purified by organic solvent extraction and silica gel chromatography. Narasin is active in vitro against gram-positive bacteria, anaerobic bacteria, and fungi and is effective in protecting chickens from coccidial infections.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002645:Chickens; D003049:Coccidiostats; D004352:Drug Resistance, Microbial; D005658:Fungi / Q000187:drug effects; D007928:Lethal Dose 50; D051379:Mice; D014780:Viruses / Q000187:drug effects
D000900:Anti-Bacterial Agents; D003049:Coccidiostats