[Relationship of inotropic vagal effects to stretching of the atrium].
Isolated left rabbit atria were tested. Preparations are vagal innervated and driven by a constant frequency. Isovolumetric contractions, volumes of the auricles and intraatrial pressures were recorded. With increasing intraatrial pressure the effectivity of peripheral nerve-ending stimulation decreases. There exists a critical value of atrial area. The vagal effectivity will decrease rapidly, if the atrial surface increases higher than this critical value by stretching the auricles.
D000818:Animals; D001794:Blood Pressure; D005260:Female; D006325:Heart Atria / Q000294:innervation*; D008297:Male; D008465:Mechanoreceptors; D009200:Myocardial Contraction; D011817:Rabbits; D014630:Vagus Nerve / Q000502:physiology*
Dei Abhängigkeit inotroper Vaguswirkungen von der Dehnung des Vorhofmyokards.