5-hydroxytryptamine induced changes in body temperature of newborn kittens and guinea-pigs and the effect of indomethacin thereon.
During the first days of life 10 microgram i.c.v. 5-HT evoked a primary, short-lasting hyperthermia in kittens and hypothermia in guinea-pigs. In both species, a secondary late hyperthermia occurred that could be prevented by indomethacin pretreatment.
D000818:Animals; D000831:Animals, Newborn; D001831:Body Temperature / Q000187:drug effects*; D002415:Cats; D006168:Guinea Pigs; D007213:Indomethacin / Q000494:pharmacology*; D011453:Prostaglandins / Q000096:biosynthesis; D012701:Serotonin / Q000494:pharmacology*
D011453:Prostaglandins; D012701:Serotonin; D007213:Indomethacin