[Estrogen receptors and nuclear translocation in C3H independent mouse mammary tumors (author's transl)].
In C3H independent mouse mammary tumors, estrogen receptors were characterized and analyzed using dextrancoated charcoal, protamine sulfate and hydroxyapatite assays. The mean concentration of cytosol receptors was of 18.5 +/- 3.5 femtomoles per mg of protein stating that C3H tumor was a "receptor-positive" tumor. The cytosol estrogen-receptor complexes were translocated in vivo to the nucleus thus suggesting that the hormone-independency of the C3H tumor should be searched in later steps of the estradiol mechanism of action.
D000818:Animals; D008325:Mammary Neoplasms, Experimental / Q000032:analysis*; D008722:Methods; D051379:Mice; D008809:Mice, Inbred C3H; D011960:Receptors, Estrogen / Q000032:analysis*
D011960:Receptors, Estrogen
Récepteurs des oestrogènes et translocation nucléaire dans les tumeurs mammaires indépendantes de souris C3H.