[Effect of "pasteurizing" doses of ionizing radiations on the drug resistance of microorganisms isolated in pharmaceutical chemical manufacture].
Changes in the antibioticograms after a single irradiation of dry cultures of microorganisms isolated at a pharmaceutical factory were noted in 0.5 per cent of 686 microbial strains tested. Restoration of sensitivity to one or more often several antibiotics was found in the microbes with the changed antibioticograms. After a three-fold irradiation the value increased to 9 per cent. Development of the drug resistance in the microbes neither after the single nor after the three-fold irradiation was observed.
D001419:Bacteria / Q000528:radiation effects; D002509:Cephaloridine / Q000494:pharmacology; D003470:Culture Media; D004307:Dose-Response Relationship, Radiation; D004340:Drug Contamination / Q000517:prevention & control*; D004345:Drug Industry; D004352:Drug Resistance, Microbial / Q000528:radiation effects*; D009031:Moscow; D013210:Staphylococcus / Q000528:radiation effects; D013291:Streptococcus / Q000528:radiation effects; D015003:Yeasts / Q000528:radiation effects
D003470:Culture Media; D002509:Cephaloridine
Vliianie "pasterizuiushchikh" doz ioniziruiushchikh izlucheniĭ na lekarstvennuiu chuvstvitel'nost' mikroorganizmov, vydelennykh na khimiko-farmatsevticheskom proizvodstve.