[Topical treatment of some dystrophic and inflammatory lesions of the skin and soft tissues].
An investigation has been carried out on lysozyme cleasing antiphlogistic granulogenic activity when topically applied to various lesions such as varicous ulcers, bed sores, herpetic infections or actinic ulcerative processes. 38 patients who had undergone surgery and were affected with these lesions, were treated with lysozyme ointment applied twice daily for 15 days. Parameters for evaluating the therapeutic effect of the drug were, besides the typical subjective symptomatology, planimetry of the lesions, hyperemia and perilesional erythema. At the end of the investigation it was observed that lysozyme applications had favourable restorative effects and, in the case of herpetic lesions, complete resolution was achieved. Tolerance was satisfactory, although in 2 cases treatment had to be precautionarily discontinued having the subject complained of reacutization of pruritus.
D000328:Adult; D000368:Aged; D003872:Dermatitis / Q000188:drug therapy; D005260:Female; D006561:Herpes Simplex / Q000188:drug therapy; D006562:Herpes Zoster / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009113:Muramidase / Q000627:therapeutic use*; D009824:Ointments; D003668:Pressure Ulcer / Q000188:drug therapy; D012871:Skin Diseases / Q000188:drug therapy*; D012883:Skin Ulcer / Q000188:drug therapy; D014647:Varicose Ulcer / Q000188:drug therapy
D009824:Ointments; D009113:Muramidase
Trattamento topico di alcune lesioni distrofiche e flogistiche della cute e dei tessuti molli.