[RNA-polymerase of murine leukemia L1210 cells].
Multiple forms of RNA polymerases (I, II and III) from murine leukemia L1210 cells are solubilized, purified and characterized. Heterogeneity of RNA polymerases I and III is revealed by chromatography on DEAE-Sephadex and Phosphocellulose (P-11). The properties of these forms such as peculiarities of transcription of native and denaturated DNA, metal ion dependence (Mg2+, Mn2+ and (NH4)2SO4) and alpha-amanitin sensitivity resemble those reported for other mammalian RNA polymerases. The level of RNA polymerase I of leukemia L1210 cells increase approximately ten-fold relative to its level in some organs of healthy mice.
D000818:Animals; D012321:DNA-Directed RNA Polymerases / Q000302:isolation & purification* / Q000378:metabolism; D007939:Leukemia L1210 / Q000201:enzymology*; D051379:Mice; D012318:RNA Polymerase I / Q000302:isolation & purification; D012319:RNA Polymerase II / Q000302:isolation & purification; D012320:RNA Polymerase III / Q000302:isolation & purification; D014158:Transcription, Genetic
D012319:RNA Polymerase II; D012321:DNA-Directed RNA Polymerases; D012318:RNA Polymerase I; D012320:RNA Polymerase III
RNK-polimeraza kletok limfoleĭkoza L1210 myshei.