Does increased gastric mucus play a role in the ulcer-protecting effects of zinc sulphate?
Zinc sulphate pretreatment i.p. produces dose-related reductions in stess ulcer incidence in pylorus-occluded rats. The associated increases in gastric wall mucus, in stressed and nonstressed animals, suggest that a similar effect may contribute to its ulcer-reducing ability in man.
D000818:Animals; D005753:Gastric Mucosa / Q000378:metabolism; D008297:Male; D010437:Peptic Ulcer / Q000517:prevention & control*; D051381:Rats; D013312:Stress, Physiological; D013431:Sulfates / Q000008:administration & dosage / Q000627:therapeutic use; D015032:Zinc / Q000008:administration & dosage / Q000627:therapeutic use*
D013431:Sulfates; D015032:Zinc