In vitro and in vivo comparison of single-donor platelets and multiple-donor pooled platelets transfusions in leukemic patients.
In vitro and in vivo studies were done to evaluate efficacy of fresh, single donor platelets (SDP) obtained by Latham-bowl plateletpheresis and multiple donor, pooled platelets (MDPP) obtained by conventional centrifugation for transfusion of leukemic patients. Results indicate increased effectiveness, both in vitro and in vivo, of single donor platelets as compared to multiple donor pooled platelets.
D000255:Adenosine Triphosphate / Q000097:blood; D000577:Amides / Q000097:blood; D001780:Blood Coagulation Tests; D001782:Blood Donors; D001803:Blood Transfusion; D002952:Citric Acid Cycle; D006801:Humans; D007938:Leukemia / Q000628:therapy*; D017713:Platelet Transfusion; D013997:Time Factors
D000577:Amides; D000255:Adenosine Triphosphate