Brain death: II. Neuropathological correlation with the radioisotopic bolus technique for evaluation of critical deficit of cerebral blood flow.
Diffuse necrosis and autolysis were found in the brains from 6 comatose, respirator-supported patients in whom the bolus technique demonstrated no cerebral blood flow during a period exceeding 20 hours prior to cardiac death. When blood flow was insufficient to produce a bolus, there was no evidence of active tissue response to necrosis. In 6 similar patients, when cerebral blood flow was detected by the bolus technique, less extensive necrosis was observed postmortem and there was active tissue response.
D001049:Apnea / Q000473:pathology; D001329:Autolysis / Q000473:pathology; D001921:Brain / Q000473:pathology*; D001926:Brain Death; D002560:Cerebrovascular Circulation; D003128:Coma / Q000473:pathology; D004569:Electroencephalography; D006801:Humans; D008722:Methods; D009336:Necrosis; D009474:Neurons / Q000648:ultrastructure; D013667:Technetium
D013667:Technetium