The prevention of invasive cancer of the rectum.
The results of the 25+ year Cancer Detection Center study, including 20,000 participants and 100,000+ patient-years experience, demonstrate the obviation of appearance of most lower bowel cancers associated with a program of proctosigmoidoscopy and adenomatous polyp removal. Once on a schedule of periodic examinations, study participants developed only a fraction of the anticipated number of rectal cancers; most of the cancers which did develop were detected while at an early stage and with involvement of only the mucosa. Not a single death from lower bowel cancer has occurred among active study participants or for 7+ years following the most recent examination at the Center.
D000230:Adenocarcinoma / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D011230:Precancerous Conditions / Q000175:diagnosis* / Q000601:surgery; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000517:prevention & control* / Q000601:surgery; D012812:Sigmoidoscopy