The cell surface antigen A, B or O(H) as an indicator of malignant potential in stage A bladder carcinoma: preliminary report.
The presence or absence of cell surface antigens (A,B and H) on the cell surface of bladder tumors has been studied. The major blood group antigens A, B or O(H) are present on normal bladder epithelium but are not present on some low grade and low stage papillary transitional cell carcinomas of the bladder. We have demonstrated that of 5 stage A bladder tumors that have not recurred in at least 5 years 3 retained the cell surface antigens, while tumors that have recurred locally, invaded or metastasized had lost these cell surface antigens on the original stage A tumor.
D000017:ABO Blood-Group System; D002295:Carcinoma, Transitional Cell / Q000276:immunology* / Q000473:pathology; D002462:Cell Membrane / Q000276:immunology*; D006801:Humans; D009362:Neoplasm Metastasis; D012008:Recurrence; D001749:Urinary Bladder Neoplasms / Q000276:immunology* / Q000473:pathology
D000017:ABO Blood-Group System