[The importance of man, mouse and rat skin surface lipid fractions on the "in vitro" penetration of "Schistosoma mansoni" cercariae (author's transl)].
The AA. have studied in this research, the rôle explicated in vitro from the lipids contained in a man's skin, in a rat of the Wistar experimental group and in a mouse of the Swiss one. They have seen that some lipids fractions, as triglycerides, waxes and squalenes explicate an action that favours the penetration of the cercariae in vitro on a plate of agar and that such an action is due to the unsaturation in the above said fractions of sebaceous origin. On the contrary the lipids of skin origin as sterols and their esters inhibit the penetration.
D000818:Animals; D006801:Humans; D066298:In Vitro Techniques; D007814:Larva; D050356:Lipid Metabolism; D008055:Lipids; D051379:Mice; D051381:Rats; D012550:Schistosoma mansoni; D012867:Skin / Q000378:metabolism / Q000469:parasitology*; D013185:Squalene / Q000494:pharmacology; D014280:Triglycerides / Q000494:pharmacology; D014885:Waxes / Q000494:pharmacology
D008055:Lipids; D014280:Triglycerides; D014885:Waxes; D013185:Squalene
L'importanza delle frazioni lipidiche cutanee di uomo, di topo e di ratto nella penetrazione "in vitro" delle cercarie di "Schistosoma mansoni".