Induction of labor in the high-risk pregnancy with PGF 2 alpha.
The induction of labor in the high-risk patient is accompanied by an increased incidence of cesarean section partly due to failed induction. A series of 50 high-risk patients induced with intravenous prostaglandin F 2 alpha is presented. Forty-five were successfully induced, 35 of whom delivered vaginally. Failed inductions occurred in 5 patients. The overall success rate was 90%, and cesarean section rate was 25.5%. There was an increased incidence of late decelerations in the PGF 2 alpha groups as compared to spontaneous and Pitocin-stimulated labors. While the success was high, the use of a drug which itself may caused fetal cardiovascular changes is not desirable, especially in those pregnancies already at risk.
D000293:Adolescent; D000328:Adult; D002585:Cesarean Section; D005260:Female; D005318:Fetal Heart / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced; D009325:Nausea / Q000139:chemically induced; D011247:Pregnancy; D011460:Prostaglandins F / Q000009:adverse effects / Q000627:therapeutic use*; D012306:Risk; D013997:Time Factors; D014839:Vomiting / Q000139:chemically induced
D011460:Prostaglandins F