Production of Venezuelan equine encephalitis virus in cells grown on artificial capillaries.
Primary cell cultures, a continuous cell line, and a diploid cell line were grown on an artificial capillary system. The cells were subsequently infected with Venezuelan equine encephalitis virus, and viral replication was studied. Extracellular fluids harvested from this system contained high titers of virus and were relatively free of cell debris.
D002460:Cell Line; D002478:Cells, Cultured; D004666:Encephalitis Virus, Venezuelan Equine / Q000254:growth & development*; D014776:Virus Cultivation / Q000295:instrumentation / Q000379:methods*