[Data on the biological properties of olefin sulfate].
In the experiments on hybrid mice CBA X C57Bl6 the effect of the preparation Progress with different (16.5% and 24.5%) content of the surface-active agent--olefine sulphate on benz(a)pyrene induced carcinogenesis has been studied. The cutaneous application of the substance has evidenced enhanced carcinogenesis under the exposure to a larger of the two dosages: skin tumors in the experimental group were noted in 68.75% of animals, in the control group (application of the carcinogen)--in 19.44%. Under the condition of peroral administration of the agent no enhancement of carcinogenesis was revealed, meanwhile proventricular tumors appeared in the group where the carcinogen was administered without the preliminary carcinogen exposure.
D000284:Administration, Oral; D000287:Administration, Topical; D000475:Alkenes; D000818:Animals; D002273:Carcinogens; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009374:Neoplasms, Experimental / Q000139:chemically induced; D012878:Skin Neoplasms / Q000139:chemically induced; D013464:Sulfuric Acids; D013501:Surface-Active Agents; D013997:Time Factors
D000475:Alkenes; D002273:Carcinogens; D013464:Sulfuric Acids; D013501:Surface-Active Agents
Nekotorye dannye o biologicheskikh svoĭstvakh olefinsul'fata.