Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.
D002460:Cell Line; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D005796:Genes; D014644:Genetic Variation; D007700:Kinetics; D008727:Methotrexate / Q000494:pharmacology*; D009693:Nucleic Acid Hybridization; D011132:Polyribosomes / Q000201:enzymology; D012333:RNA, Messenger / Q000378:metabolism; D013762:Tetrahydrofolate Dehydrogenase / Q000096:biosynthesis / Q000235:genetics*
D004273:DNA, Neoplasm; D012333:RNA, Messenger; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate