Induction of developmental anomalies in mice by maternal stress.
The short-time restraint of pregnant mice on day 8 of gestation led to a significant increase of the anomaly rate in fetuses. This effect may be due to stress factors of endocrine origin.
D000818:Animals; D000013:Congenital Abnormalities / Q000209:etiology*; D005260:Female; D005865:Gestational Age; D011247:Pregnancy; D011270:Pregnancy, Animal; D051381:Rats; D013312:Stress, Physiological / Q000150:complications*