Glycolytic substrate utilization and energy consumption in the cerebral hemispheres of the mouse during experimental anuria.
The glycolytic substrate utilization and energy consumption of hemispheres of adult mice were studied by converting the heads into a closed system by decapitation. It was concluded that progressive insufficiency of renal function is paralleled by an increase in brain permeability for glucose and a progressive reduction in brain energy metabolism.
D000208:Acute Disease; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001002:Anuria / Q000378:metabolism*; D001786:Blood Glucose / Q000032:analysis; D001921:Brain / Q000378:metabolism*; D002463:Cell Membrane Permeability; D004734:Energy Metabolism; D006003:Glycogen / Q000378:metabolism; D006019:Glycolysis; D008297:Male; D051379:Mice; D010101:Oxygen Consumption; D010725:Phosphocreatine / Q000378:metabolism; D014508:Urea / Q000097:blood / Q000378:metabolism
D001786:Blood Glucose; D010725:Phosphocreatine; D000255:Adenosine Triphosphate; D014508:Urea; D006003:Glycogen