A lack of correlation between rat kidney mitochondrial swelling and glutaminase activation in metabolic acidosis.
We found no overall correlation between mitochondrial swelling and PDG activity under many different conditions. We conclude that augmented PDG activity in acidosis is not related, at least to any great extent, to increased anion permeability produced by mitochondrial swelling.
D000138:Acidosis / Q000139:chemically induced / Q000201:enzymology*; D000818:Animals; D004789:Enzyme Activation / Q000187:drug effects; D005972:Glutaminase / Q000378:metabolism*; D007668:Kidney / Q000187:drug effects / Q000502:physiology; D008933:Mitochondrial Swelling / Q000187:drug effects; D010710:Phosphates / Q000494:pharmacology; D051381:Rats
D010710:Phosphates; D005972:Glutaminase