Identification of the hairy cells of leukaemic reticuloendotheliosis by an esterase method.
A distinctive pattern of alpha-naphthyl butyrate esterase positivity was observed in all of a series of 14 patients with HCL. This pattern was not observed in a range of other haematological malignancies including nine cases of CLL, two cases of Sézary's syndrome, six cases of null cell ALL, two cases of Schilling-type monocytic leukaemia and one case of lymphosarcoma cell leukaemia. The potential diagnostic value of this simple cytochemical test is discussed in relation to existing methods.
D000135:Acid Phosphatase / Q000097:blood; D004796:Clinical Enzyme Tests; D004950:Esterases / Q000097:blood*; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000175:diagnosis* / Q000276:immunology; D008214:Lymphocytes / Q000201:enzymology; D012397:Rosette Formation
D004950:Esterases; D000135:Acid Phosphatase