Bovine TSH-stimulation of fish thyroid peroxidase activity and role of thyroxine thereon.
bTSH augmented the fish thyroid peroxidase activity in a dose-response manner. Thyroxine could not modulate the effect of exogenous bTSH, but it decreased the peroxidase activity in a control system when administered alone. The data therefore suggest similar negative feedback control system for TSH-regulation as operative in the case of mammals.
D000818:Animals; D002417:Cattle; D005399:Fishes; D010544:Peroxidases / Q000378:metabolism*; D013961:Thyroid Gland / Q000201:enzymology*; D013972:Thyrotropin / Q000494:pharmacology*; D013974:Thyroxine / Q000494:pharmacology*
D013972:Thyrotropin; D010544:Peroxidases; D013974:Thyroxine