Splenic sequestration with sickle cell-C disease.
During an episode of pneumonia and multiple pulmonary thromboembolic events, an adult male patient with sickle cell-C hemoglobinopathy developed a severe anemia associated with rapidly increasing splenic size and diminished splenic uptake of technetium Tc 99m sulfur colloid, indicating diminished splenic function due to hypersequestration, a rare and noteworthy phenomenon in adult patients with sickle cell-C disease.
D000208:Acute Disease; D000328:Adult; D006445:Hemoglobin C Disease / Q000150:complications*; D006801:Humans; D006971:Hypersplenism / Q000175:diagnosis / Q000209:etiology*; D008099:Liver / Q000000981:diagnostic imaging; D008297:Male; D011018:Pneumonia, Pneumococcal / Q000150:complications; D011655:Pulmonary Embolism / Q000150:complications; D011877:Radionuclide Imaging; D013154:Spleen / Q000000981:diagnostic imaging; D013163:Splenomegaly / Q000175:diagnosis / Q000209:etiology*