Fetal effects of cadmium in pregnant rats on normal and zinc deficient diets.
This investigation has shown that not only the extent of fetal resoprtion and malformation but also the types of malformation seen in rats depend upon the strain used and day of gestation. Furthermore, the effects of zinc deficiency and cadmium administration on the fetus can be at least additive, as was seen for malformations. For fetal resorption, zinc deficiency potentiated the action of cadmium.
D000014:Abnormalities, Drug-Induced; D000821:Animal Feed; D000818:Animals; D002104:Cadmium / Q000633:toxicity*; D005260:Female; D005333:Fetus / Q000187:drug effects*; D005865:Gestational Age; D011247:Pregnancy; D011270:Pregnancy, Animal; D051381:Rats; D015032:Zinc / Q000172:deficiency*
D002104:Cadmium; D015032:Zinc