Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001667:Binding, Competitive; D002478:Cells, Cultured; D002784:Cholesterol / Q000096:biosynthesis; D004790:Enzyme Induction / Q000187:drug effects; D005347:Fibroblasts / Q000201:enzymology; D006801:Humans; D006903:Hydroxymethylglutaryl CoA Reductases / Q000096:biosynthesis*; D007700:Kinetics; D008148:Lovastatin / Q000031:analogs & derivatives; D009281:Naphthalenes / Q000494:pharmacology; D010407:Penicillium; D012867:Skin / Q000201:enzymology*
D000900:Anti-Bacterial Agents; D009281:Naphthalenes; C012258:mevastatin; D002784:Cholesterol; D008148:Lovastatin; D006903:Hydroxymethylglutaryl CoA Reductases