Syntheses and biological activities of basically substituted isoalloxazines.
A number of flavins possessing a 2-[bis(2-hydroxyethyl)aminolethyl side chain in place of the usual D-ribityl side chain at position 10 have been synthesized and evaluated for riboflavin antagnostic activity in the rat. Two flavins of those synthesized are potent antagonists of the vitamin.
D000818:Animals; D005260:Female; D005415:Flavins / Q000138:chemical synthesis / Q000494:pharmacology*; D051381:Rats; D012256:Riboflavin / Q000037:antagonists & inhibitors*
D005415:Flavins; D012256:Riboflavin