[Measurement of post-irradiation population kinetics using single-cell cytophotometry combined with double-labeling autoradiography: model investigations into a diploid Ehrlich ascites tumor after 475 rd X-irradiation (author's transl)].
A technique for in vivo determination of the population kinetics in tumors following irradiation is reported in this paper. Using the model of a diploid Ehrlich ascites tumor (EAT-dipl), the migration of cells from different subpopulations was followed up through the generation cycle. The measurability of post-irradiation growth kinetics in different subpopulations is emphasized with regard to its importance for practical application with combination treatments or possibility for the problem of dose-time relations. The individual results obtained after 475 rd are presented in detail.
D000818:Animals; D001345:Autoradiography; D002286:Carcinoma, Ehrlich Tumor / Q000532:radiotherapy*; D002453:Cell Cycle; D002455:Cell Division; D002465:Cell Movement / Q000528:radiation effects*; D008297:Male; D051379:Mice; D008940:Mitotic Index; D010783:Photometry; D011879:Radiotherapy Dosage; D013997:Time Factors
Die Messung der Populationskinetik nach Bestrahlung durch Kombination von Einzelzellzytophotometrie und zweizeitiger Markierungsautoradiographie. Modelluntersuchungen an einem diploiden Ehrlich-Aszites-Tumor nach 475 rd Röntgenbestrahlung.