Fractional fatty acid incorporation into human adipose tissue (FIAT) in hypertriglyceridemia.
Two processes regulate the removal of lipoprotein triglycerides from plasma: (1) hydrolysis of triglycerides by lipoprotein lipase to fatty acids in the capillaries; (2) local uptake and esterification of fatty acids by adipose tissue, muscle and other tissues. This second process has been studied on needle biopsy specimens of adipose tissue from normotriglyceridemic and hypertriglyceridemic subjects. Hypertriglyceridemie was found to be associated to low fatty acid incorporation into adipose tissue.
D000273:Adipose Tissue / Q000378:metabolism*; D000328:Adult; D005227:Fatty Acids / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D006801:Humans; D006949:Hyperlipidemias / Q000378:metabolism*; D014280:Triglycerides / Q000097:blood*
D005227:Fatty Acids; D014280:Triglycerides; D005947:Glucose