[Neuroactive compounds and vertebral teratogenesis in the bird embryo (author's transl)].
Anticholinesterasic and depolarizing (analogues of acetylcholine) agents administered to quail embryos after 3 days of incubation give rise to vertebral fusions in addition to neck deformities. Antagonists of acetylcholine (gallamine and hexamethonium) produce only vertebral joint fusions. The incidence of all these compounds in the vertebral defects by the way of there neuroactive properties is proposed.
D000014:Abnormalities, Drug-Induced / Q000473:pathology*; D000818:Animals; D002574:Cervical Vertebrae / Q000002:abnormalities*; D002800:Cholinesterase Inhibitors / Q000633:toxicity*; D005703:Gallamine Triethiodide / Q000633:toxicity; D006584:Hexamethonium Compounds / Q000633:toxicity; D007306:Insecticides / Q000633:toxicity; D009943:Organophosphorus Compounds; D010830:Physostigmine / Q000633:toxicity; D011784:Quail / Q000196:embryology*; D013723:Teratogens
D002800:Cholinesterase Inhibitors; D006584:Hexamethonium Compounds; D007306:Insecticides; D009943:Organophosphorus Compounds; D013723:Teratogens; D010830:Physostigmine; D005703:Gallamine Triethiodide
Neuroactifs et tératogenèse vertébrale chez l'embryon d'oiseau.