Giardiasis with total villous atrophy.
A patient who developed symptomatic giardiasis after a tour of the Soviet Union is presented. The diagnosis was established by duodenal aspiration. A small intestinal biopsy revealed total villous atrophy in the absence of celiac sprue or a gastrointestinal immunodeficiency syndrome, a finding not previously described. The biopsy remains normal after a single course of metronidazole (Flagyl), despite subsequent exposure to gluten.
D001284:Atrophy; D001706:Biopsy; D005260:Female; D005873:Giardiasis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007411:Intestinal Diseases, Parasitic / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D007413:Intestinal Mucosa / Q000473:pathology*; D007421:Intestine, Small / Q000473:pathology; D008795:Metronidazole / Q000627:therapeutic use; D008875:Middle Aged; D014586:USSR
D008795:Metronidazole