[Content of placental lactogen in the blood of pregnant women with diabetes mellitus].
The content of placental lactogenic hormone (PLH), one of the indices of the hormonal function of the placenta, was studied in the blood of pregnant women suffering from diabetes mellitus, depending on the compensation of the disease and the presence of complications in pregnancy. Despite the high weight of placenta, usually observed in this pathology in pregnant women, the blood PLH level did not significantly exceed that in normally coursing pregnancy. In case of decompensated diabetes mellitus there was a significantly lower blood PLH level in comparison with that in the compensated one, this pointing to the direct influence of metabolic disturbances characteristic of decompensated diabetes mellitus on the hormonal function of the placenta. The lowest PLH level was found in the patients with diabetes mellitus at the period of decompensation of the disease in the presence of complications in pregnancy. An unfavourable influence of decompensated diabetes mellitus on the hormonal function of the placenta and the known data on the fact that decompensated diabetes mellitus promoted the development of complications in pregnancy, also deranging the placental function, confirmed the necessity of compensation of the disease during pregnancy.
D000328:Adult; D005260:Female; D006801:Humans; D010920:Placenta / Q000378:metabolism; D010928:Placental Lactogen / Q000097:blood*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011254:Pregnancy in Diabetics / Q000378:metabolism*
D010928:Placental Lactogen
Soderzhanie platsentarnogo laktogennogo gormona v krovi u beremennykh zhenshchin, bol'nykh sakharnym diabetom.