The use of intravenous lignocaine in the diagnosis and treatment of tinnitus.
The effect of intravenous lignocaine upon the symptom of tinnitus has been assessed in seventy-eight patients and the results correlated with associated hearing loss. Lignocaine appears to be highly effective in suppressing tinnitus in patients with presumed damage or degeneration of the Organ of Corti and is less effective in other groups. It is postulated that tinnitus in patients with Organ of Corti damage is the result of abnormal hyperactivity in the auditory pathway following deafferentation.
D001309:Auditory Threshold; D003638:Deafness / Q000628:therapy; D006801:Humans; D008012:Lidocaine / Q000627:therapeutic use*; D014012:Tinnitus / Q000175:diagnosis / Q000188:drug therapy*
D008012:Lidocaine