The local hemodynamic effects of operation in a bloodless field.
Skeletal muscle blood flow and transport function were investigated in 25 patients operated on for a knee injury in a bloodless field. With a double-isotope-clearance technique, measurements were carried out in the operated leg immediately after re-establishment of blood flow, and 1-2 days postoperatively in both the operated and the non-operated leg. A significant increase in blood flow and transport function was registered immediately after release of the tourniquet. The initial maximal hyperemic flow and transport responses were inversely related to the duration of the occlusion. The peak of the blood flow response was more marked and somewhat earlier in the patients with a short duration of occlusion (less than or equal to 60 min) than in those with longer occlusions. 9 of 16 operated legs showed a maximal transport function 1-2 days postoperatively. Peripheral vascular resistance decreased after re-establishment of blood flow. The blood flow in the non-operated leg showed no changes after release of the tourniquet in the operated leg.
D000328:Adult; D002200:Capillary Resistance; D005260:Female; D006801:Humans; D007511:Ischemia; D007718:Knee Injuries / Q000601:surgery*; D007866:Leg / Q000098:blood supply*; D008297:Male; D008722:Methods; D009132:Muscles / Q000098:blood supply*; D012039:Regional Blood Flow; D014111:Tourniquets; D014655:Vascular Resistance