[Chemically induced stomach carcinomas in rats following vagotomy and Bilroth II gastrectomy].
180 Wistar-rats were daily exposed to 30 and 100 mg MNNG/1000 ccm tapwater. After an exposure of 7 weeks a truncal vagotomy with pyloroplasty or a Billroth II-resection was performed in 25 animals of each dosage-group. 80 rats were not operated. The incidence of carcinomas in the Billroth II-rats of both dosage-groups was evidently higher than in the exposed controls. In the vagotomized rats an increased occurrence of carcinomas could not be observed.
D000818:Animals; D005743:Gastrectomy / Q000379:methods; D008297:Male; D008769:Methylnitronitrosoguanidine; D009374:Neoplasms, Experimental / Q000139:chemically induced; D051381:Rats; D012306:Risk; D013274:Stomach Neoplasms / Q000139:chemically induced*; D014628:Vagotomy
D008769:Methylnitronitrosoguanidine
Die chemische Erzeugung von Magencarcinomen bei der Ratte nach Vagotomie und Magensektion nach Billroth II.