The nonspecific nature of fibrin thrombi in ischemic bowel disease.
Twenty cases of ischemic bowel disease were analysed to determine the frequency and significance of fibrin thrombi in this condition. Fibrin thrombi were present in all 10 patients with occlusive ischemic bowel disease and in 7 of the 10 patients with nonocclusive ischemic bowel disease. In addition, fibrin thrombi were noted in a wide variety of specific and nonspecific inflammatory bowel diseases and in acute appendicitis. We conclude that fibrin thrombi are a nonspecific feature of tissue necrosis and that their mere presence in the bowel should not be regarded as an expression of disseminated intravascular coagulation.
D001064:Appendicitis / Q000150:complications; D003093:Colitis, Ulcerative / Q000150:complications; D003424:Crohn Disease / Q000150:complications; D005337:Fibrin; D006801:Humans; D007410:Intestinal Diseases / Q000150:complications; D007415:Intestinal Obstruction / Q000150:complications; D007422:Intestines / Q000098:blood supply* / Q000473:pathology; D007511:Ischemia / Q000209:etiology*; D009336:Necrosis; D013927:Thrombosis / Q000209:etiology* / Q000473:pathology
D005337:Fibrin