SEM evaluation of endothelial damage following temporary middle cerebral artery occlusion in dogs.
Microsurgical clips and tourniquets were used to occlude middle cerebral arteries of dogs for 45-minute periods. Scanning electron microscopy and light microscopy studies revealed significant endothelial damage in many of these arteries. Less traumatic microsurgical clips are needed for temporary small vessel occlusion.
D000818:Animals; D002536:Cerebral Arteries / Q000601:surgery / Q000648:ultrastructure*; D004285:Dogs; D004727:Endothelium / Q000648:ultrastructure; D002532:Intracranial Aneurysm / Q000601:surgery; D008855:Microscopy, Electron, Scanning; D008866:Microsurgery / Q000295:instrumentation*; D011312:Pressure; D013525:Surgical Instruments / Q000009:adverse effects*