Di-2-ethylhexylphthalate (DEHP) content of blood or blood components stored in plastic bags.
Di-2-ethylhexylphthalate (DEHP) is a plasticizer used in the manufacture of plastic bags for blood products, which may be toxic. No more than a trace (less than 0.1 microgram/ml) could be detected in anticoagulants in blood bags, or in the blood of healthy untransfused subjects. A mean of 23 microgram/ml was found in ACD whole blood after 2 weeks storage, and 46 microgram/ml after 3 weeks; the corresponding figures for packed cells were 39 and 45 microgram/ml. The level in CPD whole blood was similar. Fresh frozen plasma and cryoprecipitate contained 7 microgram/ml, while levels of 1.0 and 0.7 microgram/ml of DEHP were found in the blood of two patients who had received massive transfusions. Most DEHP in stored blood was associated with plasma lipoproteins.
D000925:Anticoagulants; D001793:Blood Preservation; D055598:Chemical Phenomena; D002621:Chemistry; D002951:Citrates; D004051:Diethylhexyl Phthalate / Q000032:analysis / Q000097:blood*; D006801:Humans; D010795:Phthalic Acids / Q000097:blood*; D010949:Plasma; D013997:Time Factors
D000925:Anticoagulants; D002951:Citrates; D010795:Phthalic Acids; D004051:Diethylhexyl Phthalate