Cardiac arrhythmias after intravenous administration of glucagon.
The effect of glucagon on the circulatory system was studied in 22 healthy men. The drug was administered in doses of 50 microgram/kg of body weight for 30 sec. In the case of 5 subjects, arrhythmias occurred that manifested themselves as ventricular and supraventricular extrasystoles. In the case of 1 subject, who had sporadic ventricular fusion beats in the preexamination period, the arrhythmia increased following glucagon injection.
D000328:Adult; D001145:Arrhythmias, Cardiac / Q000097:blood / Q000139:chemically induced*; D001786:Blood Glucose / Q000032:analysis; D004562:Electrocardiography; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005934:Glucagon / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D011188:Potassium / Q000097:blood
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D005934:Glucagon; D011188:Potassium