Lens differentiation. Crystallin synthesis in isolated epithelia from calf lenses.
In the calf eye lens, four morphologically distinct cell types can be detected: three in the epithelial monolayer and one in the cortical part. During differentiation, there is a quantitative change in the synthesis of crystallin subunits. A marked increase in alphaA-chains and several beta-crystallin polypeptides accompanies the transition from epithelial to fiberlike lens cells while synthesis of the non-crystallin proteins diminishes significantly.
D000818:Animals; D001345:Autoradiography; D002417:Cattle; D002454:Cell Differentiation; D003459:Crystallins / Q000096:biosynthesis*; D004848:Epithelium / Q000378:metabolism / Q000648:ultrastructure; D007908:Lens, Crystalline / Q000378:metabolism* / Q000648:ultrastructure; D008970:Molecular Weight
D003459:Crystallins