Effect of gold salts on the IgE immune response in mice.
In vivo effect of gold salts on the IgE immune response was investigated in mice and rats. It was demonstrated that gold salts did not suppress but rather enhanced the antigen-specific IgE immune response in mice. Moreover, gold salt had on mast cell degranulation in vivo in rats.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D005260:Female; D006046:Gold / Q000494:pharmacology*; D007073:Immunoglobulin E; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010323:Passive Cutaneous Anaphylaxis; D051381:Rats
D007073:Immunoglobulin E; D006046:Gold