[DNA-synthesis and DNA-repair in chronic rheumatism influenced by small doses of natural radioactivity (radon)].
Elevated natural radioactivity during a treatment at Badgastein (Austria) caused an increase in DNA-repair of lymphocytes of patients with ankylosing spondylitis and osteoarthritis. Semiconservative DNA-synthesis was remarkably lower after the treatment in patients with ankylosing spondylitis and a small decrease was obtained also in lymphocytes of osteoarthritis patients. These effects are discussed in relation to late effects.
D001317:Austria; D001452:Balneology; D002908:Chronic Disease; D004247:DNA / Q000096:biosynthesis*; D004260:DNA Repair / Q000528:radiation effects*; D006294:Health Resorts; D006801:Humans; D007592:Joint Diseases / Q000378:metabolism / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D011879:Radiotherapy Dosage; D011886:Radon / Q000008:administration & dosage / Q000627:therapeutic use*; D013167:Spondylitis, Ankylosing / Q000378:metabolism / Q000532:radiotherapy*
D004247:DNA; D011886:Radon
DNA-Synthese und DNA-Repair bei chronischem Rheumatismus unter Einwirkung kleiner Dosen natürlicher Radioaktivität (Radon).