[Electron microscopic study of the myocardium in cyanide poisoning].
Effect of the KCN poisoning on the cardiac muscle was studied by the aid of electron microscopic cytochemical methods. The early lesions revealed were: alterations in the region of the Z-lines, "septum formation" in the mitochondria, crystolysis, enlargment of the sarcotubules. Later destruction of the thick and thin filaments alteration of the intercalar discs were observed. Activity of the succinate-dehydrogenase and cytochromoxydase decreased. Authors emphasize the non-specific character of the alterations described.
D000818:Animals; D003486:Cyanides / Q000506:poisoning*; D006801:Humans; D008929:Mitochondria, Heart / Q000648:ultrastructure; D009206:Myocardium / Q000648:ultrastructure*; D011041:Poisoning / Q000473:pathology*; D051381:Rats
D003486:Cyanides
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