[Epidural anesthesia with bupivacaine 0.75% in comparison with bupivacaine 0.5% and mepivacaine 1.5% with adrenaline (author's transl)].
147 patients undergoing low laparotomies, perineal operations and operations on the lower limbs were given bupivacaine 0.75%, bupivacaine 0.5% or mepivacain-adrenaline 1.5% for epidural anaesthesia. The anaesthesia was most effective after bupivacaine 0.75%. In this group the intensity and duration of both sensory analgesia and motor block were more prolonged. No serious complications occurred. No increase in toxicity, when using bupivacaine 0.75% (total dose of 128 mg) for epidural anaesthesia, has been shown in this clinical trial.
D000005:Abdomen / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D000767:Anesthesia, Epidural / Q000009:adverse effects; D002045:Bupivacaine; D004837:Epinephrine; D005260:Female; D006801:Humans; D007866:Leg / Q000601:surgery; D008297:Male; D008619:Mepivacaine; D008875:Middle Aged; D013997:Time Factors
D008619:Mepivacaine; D002045:Bupivacaine; D004837:Epinephrine
Epiduralanaesthesie mit Bupivacain 0,75% im Vergleich zu Bupivacain 0,5% und Mepivacain-Adrenalin 1,5%.