Effect of pentobarbital on the synaptosomal activity of acetylcholinesterase in Mongolian gerbils.
The influence of Na pentobarbital anesthesia on the activity of specific and nonspecific cholinesterase was studied in the synaptosomal fraction of Mongolian gerbils' brains. These studies have shown that this barbiturate inhibits the specific activity of acetylcholinesterase only.
D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000201:enzymology / Q000648:ultrastructure; D002091:Butyrylcholinesterase / Q000378:metabolism; D002802:Cholinesterases / Q000378:metabolism; D005849:Gerbillinae; D010424:Pentobarbital / Q000494:pharmacology*; D013574:Synaptosomes / Q000187:drug effects* / Q000201:enzymology
D000110:Acetylcholinesterase; D002091:Butyrylcholinesterase; D002802:Cholinesterases; D010424:Pentobarbital