A computer program for parenthood diagnosis within a family.
The knowledge of human polymorphism provides an efficient tool for parenthood diagnosis. This paper describes an algorithm to diagnose fatherhood within a family. In genetic research, the validation of human families is useful since at least 7% of the families have to be rejected from such studies. First, the algorithm verifies whether the phenotype of the presumed father is compatible with the genotypes of all children under the assumption of assured motherhood. An original index coding allows us to write simple algorithms: automatic creation of genetic elements, search of compatible genotypes of parentes and children. Finally, the algorithm calculates several indices used to estimate the likehood of the paternity of non-excluded man.
D003201:Computers; D005190:Family; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D008297:Male; D010334:Paternity; D010641:Phenotype