Pyoderma gangrenosum responsive to minocycline hydrochloride.
Pyoderma gangrenosum (PG) is a characteristic ulcerative condition of unknown etiology. Four cases are reported of patients with PG who responded to minocycline hydrochloride therapy. Possible mechanisms for this apparently efficacious modality are discussed.
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008911:Minocycline / Q000494:pharmacology / Q000627:therapeutic use*; D011711:Pyoderma / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D013754:Tetracyclines / Q000627:therapeutic use*
D013754:Tetracyclines; D008911:Minocycline