Liver and prostate adenocarcinoma: an "estrogen-free" environment?
We believe that the probable "estrogen-free" site which is present in the liver while a patient is on estrogens gives a conductive environment for local growth of prostate malignancy. We report 1 patient who improved with local irradiation and 2 others who stabilized and symptomatically improved with chemotherapy. Hopefully, future reports will shed more light on the treatment of hepatic metastases from prostatic adenocarcinoma.
D000230:Adenocarcinoma / Q000188:drug therapy*; D000368:Aged; D004054:Diethylstilbestrol / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D008099:Liver / Q000187:drug effects*; D008113:Liver Neoplasms / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011471:Prostatic Neoplasms / Q000188:drug therapy*
D004054:Diethylstilbestrol