Diastolic rumbles in normally functioning porcine mitral valves.
Fourteen of 22 patients (64%) with normally functioning porcine prosthetic valves in the mitral position had apical diastolic rumbles on phonocardiogram and by auscultation. Six (27%) had opening snaps. Factors necessary for the production of a diastolic rumble appear to include central flow, a flexible stent, and the presence of biologic material. Clinicians should be aware that diastolic murmurs and snaps occur in the normally functioning porcine valve.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D006326:Heart Auscultation; D006347:Heart Sounds; D006350:Heart Valve Prosthesis; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve; D010701:Phonocardiography; D013552:Swine; D014183:Transplantation, Heterologous