[Principles of optimization and scaling of certain processes in the vaccine production technology. 3. Method of determination of the optimal method of thermal sterilization of sugar solutions].
One of the most widespread methods of thermal sugar sterilization is the use of saturated water vapour under pressure in the capacity of heat source. Guaranteed sterility of solutions should be reached under conditions providing the least sugar splitting. However, in practice the integral effect of the thermal field on the solution is as a rule not taken into consideration. A new calculation method permitting to determine the amount of sugar split in the varying thermal field.
D002241:Carbohydrates; D006358:Hot Temperature; D012996:Solutions; D013242:Sterilization / Q000379:methods*; D013678:Technology, Pharmaceutical / Q000592:standards*; D014612:Vaccines / Q000592:standards*
D002241:Carbohydrates; D012996:Solutions; D014612:Vaccines
Printsipy optimizatsii i masshtabirovaniia nekotorykh protsessov v tekhnologii vaktsinnykh proizvodstv. Soobshchenie 3. Metodika opredeleniia optimal'nogo rezhima termicheskoĭ sterilizatsii rastvorov sakharov.