[Study of the antibiotic parvulomycin. The isolation of alpha,alpha-trehalose and L-glutamic acid].
A non-reducing disugar and amino acid were isolated in the studies on the structure of parvulomycin. The acid hydrolysis of the disugar revealed the presence of 2 moles of D-glucose. Acetylation of the disugar resulted in formation of octa-O-acetyl-alpha,alpha-tregalose, saponification of which resulted in formation of alpha,alpha-tregalose. Its physical parameters, i.e. melting point of the mixed sample, optical rotation, IR-spectrum coincided with those of the authentic alpha,alpha-tregalose. The isolated amino acid proved to be L-glutamic acid on thin-layer chromatography with witness and comparison of the physico-chemical properties of their hydrochlorides.
D000107:Acetylation; D000596:Amino Acids / Q000032:analysis; D000617:Aminoglycosides; D000935:Antifungal Agents / Q000032:analysis*; D002845:Chromatography; D002854:Chromatography, Paper; D004187:Disaccharides / Q000302:isolation & purification*; D005971:Glutamates / Q000302:isolation & purification*; D006027:Glycosides / Q000032:analysis; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D008968:Molecular Conformation; D014199:Trehalose / Q000302:isolation & purification*
D000596:Amino Acids; D000617:Aminoglycosides; D000935:Antifungal Agents; D004187:Disaccharides; D005971:Glutamates; D006027:Glycosides; C012472:parvulomycin; D014199:Trehalose
Issledovanie antibiotika parvulomitsina. Vydelenie al'fa,al'fa-tregalozy i L-glutaminovoĭ kisloty.