Effect of protein deprivation on extrarenal erythropoietin production.
The production of erythropoietin by rats fed a protein-deficient diet is markedly decreased. This defect can be rapidly reversed by feeding protein. In the reported experiments we investigated the effect of protein deficiency on the extra-renal production of erythropoietin. The results indicate that the production of erythropoietin in nephrectomized animals is insensitive to protein depletion.
D000818:Animals; D004044:Dietary Proteins / Q000008:administration & dosage; D004921:Erythropoietin / Q000096:biosynthesis* / Q000097:blood; D005260:Female; D006454:Hemoglobins; D000860:Hypoxia / Q000209:etiology; D007668:Kidney / Q000378:metabolism*; D009392:Nephrectomy; D011488:Protein Deficiency / Q000097:blood*; D051381:Rats
D004044:Dietary Proteins; D006454:Hemoglobins; D004921:Erythropoietin