A rapid method for the diagnosis of acute uric acid nephropathy.
Acute uric acid nephropathy is a reversible type of renal failure that results from the deposition of uric acid crystals in the collecting tubules. The present study has compared a number of laboratory tests in 5 patients with a clinical diagnosis of this disorder and 27 patients with acute renal failure of other causes. Neither the serum creatinine, BUN, serum urate concentrations, nor the ratio of serum urate:BUN differentiated between these two groups of patients. However, the ratio of uric acid to creatinine concentration on a random urine specimen did differentiate between these two patient populations. All patients with uric acid nephropathy had a ratio greater than 1.0, while all patients with other types of acute renal failure had ratios of less than 1.0.
D058186:Acute Kidney Injury / Q000150:complications / Q000175:diagnosis* / Q000652:urine; D000293:Adolescent; D002648:Child; D003404:Creatinine / Q000652:urine; D005260:Female; D006801:Humans; D007938:Leukemia / Q000150:complications; D008297:Male; D008722:Methods; D008875:Middle Aged; D014527:Uric Acid / Q000652:urine
D014527:Uric Acid; D003404:Creatinine