Genetic variants of glucose phosphate isomerase (E.C. 5.3.1.9) in canine erythrocytes.
Genetic polymorphism of glucose phosphate isomerase (GPI) was found in the erythrocytes of dogs of six Japanese breeds by using starch gel electrophoresis. Analysis of parentage records of dogs revealed that the phenotypic variation of erythrocyte glucose phosphate isomerase was controlled by one autosomal locus with two codominant alleles, GPIA and GPIB. The allele GPIB was observed in the following breeds: San'in-Shiba, Shinshu-Shiba, Shikoku, Kai and Kishu, but not in Hokkaidoes and Akitas. All the dogs belonging to 25 European breeds, 5 oriental or China-origin (except Japan) breeds examined in this experiments had the genotype constitution GPIA/GPIA, whereas one Dalmation dog was heterozygous GPIA/GPIB.
D000483:Alleles; D000818:Animals; D004285:Dogs / Q000097:blood / Q000235:genetics; D004592:Electrophoresis, Starch Gel; D004912:Erythrocytes / Q000201:enzymology; D014644:Genetic Variation; D005956:Glucose-6-Phosphate Isomerase / Q000235:genetics*; D011110:Polymorphism, Genetic
D005956:Glucose-6-Phosphate Isomerase