[Radioimmunologic determination of plasma parathormone in hypercalcemia caused by cancer with osseous metastases].
The plasma parathormone was measured by radioimmunological determination in 23 cases of cancer with bone metastases, 8 of mammary origin. In 11 cases the plasma parathormone (iPTH) was less than 4 ng/ml (lower normal limit), as might be expected in view of the hypercalcemia. In 12 cases the iPTH was higher than 4 ng/ml, in 8 of these higher than 8 ng/ml (upper normal limit). These results are suggestive of the role of a substance analogous to parathormone in the genesis of the hypercalcaemia and peritumoral bone resorption of bone metastases of solid tumors.
D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000097:blood*; D001943:Breast Neoplasms / Q000097:blood; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000097:blood* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010281:Parathyroid Hormone / Q000097:blood*; D011863:Radioimmunoassay
D010281:Parathyroid Hormone
Dosage radio-immunologique de la parathormone plasmatique dans les hypercalcémies des cancers avec métastases osseuses.