Interstitial cell tumor. Profile of hormone-producing tumor.
Interstitial cell tumor of the testis in an adult male can present with feminization and psychologic changes. The feminization and psychologic changes most likely reflect production of estrogen by the interstitial cell tumor. Removal of the tumor causes rapid return of the pituitary-testicular axis to normal, loss of feminization, and development of male psychosocial characteristics.
D000328:Adult; D004967:Estrogens / Q000378:metabolism; D005262:Feminization / Q000209:etiology; D006801:Humans; D007984:Leydig Cell Tumor / Q000150:complications / Q000378:metabolism / Q000523:psychology*; D008297:Male; D013736:Testicular Neoplasms / Q000150:complications / Q000378:metabolism / Q000523:psychology*
D004967:Estrogens