Effects of terbutaline and isoproterenol on hyperkalemia in nephrectomized rabbits.
Terbutaline, an adrenergic beta2-receptor-stimulating substance, resembled isoproterenol in its hypokalemic effect on rabbits made hyperkalemic by nephrectomy three days prior to the experiments. Both agents lowered the serum potassium values. The duration of the terbutaline effect was longer and had less influence on the cardiovascular system than had isoproterenol.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D006339:Heart Rate / Q000187:drug effects; D006947:Hyperkalemia / Q000188:drug therapy* / Q000209:etiology; D007545:Isoproterenol / Q000627:therapeutic use*; D009392:Nephrectomy; D011817:Rabbits; D013726:Terbutaline / Q000627:therapeutic use*
D007545:Isoproterenol; D013726:Terbutaline