A roentgenologic study of cortical bone resorption in chronic renal failure.
Periosteal, intracortical, and endosteal resorptive changes were evaluated in both hands and the proximal radius in 161 chronic renal-failure patients by microradioscopy, radiographic morphometry, and photodensitometry. These changes were compared to abnormalities found in skeletal surveys. A combination of microradioscopy and morphometry of hand bones was sufficiently sensitive for early detection of bone loss in renal osteodystrophy in 61% of the patients. Intracortical resorption in metacarpals appeared to be a sign of more advanced renal osteodystrophy than subperiosteal resorption in phalanges. Photodensitometric findings in the radius generally agreed with microradioscopic and morphometric findings in hand bones.
D000328:Adult; D001862:Bone Resorption / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D003720:Densitometry / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006225:Hand / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D011884:Radius / Q000473:pathology