Studies related to the metabolism of ergoline drugs. Structure determination and spectroscopic properties of 1,6-dimethyl-12-hydroxy-10alpha-ergoline derivatives.
The structure of some 1,6-dimethyl-12-hydroxy-10alpha-ergoline derivatives, related to an active metabolite of metergoline, is established by using physical methods (mass spectrometry, electronic and fluorescence spectroscopy, and 1H N.M.R. spectroscopy). The 13C N.M.R. spectrum of compound (II), 1,6-dimethyl-8beta-(acetylaminomethyl)-12-hydroxy-10alpha-ergoline, is analyzed.
D055598:Chemical Phenomena; D002621:Chemistry; D004873:Ergolines / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry / Q000379:methods; D008711:Metergoline / Q000031:analogs & derivatives / Q000032:analysis*; D013329:Structure-Activity Relationship
D004873:Ergolines; D008711:Metergoline