[Effect of space flight and of the accompanying radiation on amino acid metabolism in the skeletal muscle of rats].
It was demonstrated that a combined effect of 20.5-day space flight and gamma-irradiation reduced the content of biologically important amino acids (methionine, phenylalanine, serine, aspartic and glutamic acids) and inhibited the activity of aspartate aminotransferase of sarcoplasmatic proteins in the quadriceps muscle of rats. Comparison of these data with the Cosmos-605 results and literature reports suggested that gamma-irradiation inhibited the synthetic processes in the skeletal muscle.
D000410:Alanine Transaminase / Q000528:radiation effects; D000596:Amino Acids / Q000378:metabolism / Q000528:radiation effects*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000528:radiation effects; D004789:Enzyme Activation / Q000528:radiation effects; D005609:Free Radicals; D009132:Muscles / Q000201:enzymology / Q000528:radiation effects*; D011829:Radiation Dosage; D011839:Radiation, Ionizing / Q000009:adverse effects*; D051381:Rats; D013026:Space Flight; D013997:Time Factors
D000596:Amino Acids; D005609:Free Radicals; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
Vliianie kosmicheskogo poleta i soputstvuiushcheĭ radiatsii na aminokislotnyĭ obmen v skeletnoĭ myshtse u krys.