[Investigations of the influence of radiation therapy upon the course of the DNA repair in peripheric lymphocytes and tumorous tissues from patients with malignant disease (author's transl)].
The influence of radiation therapy upon the capacity of DNA repair in peripheric lymphocytes and tumorous tissues was studied in eleven patients with malignant manifestations. A comparison was made between the effects of short-term and of long-term irradiation. The individual cases presented differing results. An enhancement of DNA repair as well as a diminution was observed in peripheric lymphocytes as a response to irradiation. In tumorous tissues, on the contrary, a total inhibition of DNA repair was generally found.
D000368:Aged; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D004260:DNA Repair / Q000528:radiation effects*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects*; D008875:Middle Aged; D011867:Radioisotope Teletherapy; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*; D014594:Uterine Neoplasms / Q000532:radiotherapy
D003037:Cobalt Radioisotopes
Untersuchungen über den Einfluss der Strahlentherapie auf den Ablauf der DNA-Reparatur in peripheren Lymphozyten und Tumorgewebe von Patienten mit malignen Erkrankungen.