An illustration of an in-vivo corneal response to a soft lens presoaked in a non-isotonic solution.
The use of hydrophilic gel contact lenses as a carrier of a non-isotonic saline solution provokes an irreversible increase in corneal thickness in the in-vivo rabbit eye. Studies on humans confirm the nature of the animal response, and it is therefore suggested that particular care should be taken when patients prepare saline solutions.
D000818:Animals; D002712:Chlorides / Q000032:analysis; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects*; D003315:Cornea / Q000187:drug effects*; D006801:Humans; D011817:Rabbits; D012965:Sodium Chloride / Q000009:adverse effects*; D013666:Tears / Q000032:analysis
D002712:Chlorides; D012965:Sodium Chloride