The effects of eledoisin on intestinal smooth muscle of ruminants.
The effects of eledoisin on the intestinal smooth muscle of ruminants are reported. The results obtained on isolated in vitro preparations from cattle suggest a direct effect of the peptide on the smooth muscle of the different intestinal sections examined. The observations made during in vivo experiments on sheep suggest that eledoisin produces its effects by also affecting the autonomic nerve supply to the intestine of these animals.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002417:Cattle; D003106:Colon / Q000187:drug effects; D004386:Duodenum / Q000187:drug effects; D004600:Eledoisin / Q000494:pharmacology*; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D007422:Intestines / Q000187:drug effects*; D007583:Jejunum / Q000187:drug effects; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D012756:Sheep; D013373:Substance P / Q000494:pharmacology
D013373:Substance P; D004600:Eledoisin; D001285:Atropine; D000109:Acetylcholine