Altered body distribution of [99mTc] pertechnetate in iatrogenic hyperaluminemia.
Failure of intravenously administered [99mTc] pertechnetate to leave the vascular space was observed in a patient with hyperaluminemia due to treatment with an antacid drug containing aluminum hydroxide. A repeat study 3 mo after discontinuing medication, when the plasma aluminum level had fallen, revealed normal in vivo distribution of pertechnetate. It was found that instant thin-layer chromatography, using pertechnetate and an 85% methanol system, can detect plasma aluminum levels as low as 50 microgram/l.
D000328:Adult; D000535:Aluminum / Q000097:blood*; D000536:Aluminum Hydroxide / Q000009:adverse effects*; D000863:Antacids / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008467:Meckel Diverticulum / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013667:Technetium
D000863:Antacids; D000536:Aluminum Hydroxide; D013667:Technetium; D000535:Aluminum