Platelet phospholipid in stroke.
A study of platelet phospholipids in patients with stroke has been undertaken comparatively with patients without predisposition to thrombosis. An increase in the phospholipid/protein ratio in platelets was observed in patients with acute cerebrovascular accident. A significant increase of palmitoleic acid is observed in platelet phospholipids of these patients; it is accompanied by a decrease of linoleic acid. These modifications are reflected in plasma where linoleic acid is greatly diminished but where an important increase of palmitic acid is noted besides palmitoleic acid. A possible relation between higher clotting activity of platelets and those modifications in their phospholipids is discussed.
D000368:Aged; D001792:Blood Platelets / Q000378:metabolism*; D002561:Cerebrovascular Disorders / Q000097:blood*; D005227:Fatty Acids / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000097:blood*
D005227:Fatty Acids; D010743:Phospholipids