[Effect of serotoninergic substances on the brain potentials evoked by stimulation of the dental pulp].
Serotonin like M-serotonin blocking agent morphine and D-serotonin blocking agent diethalamide of lysergic acid is shown by the method of intravenous microinjections to lower and T-serotonin blocking agent tipindol--to increase the amplitude of primary responses from the dental areas of the brain cortex arising in stimulation of the dental pulp. It is suggested that the seroninergic system of the brain can through the intermediary of the M- and D-serotonin-receptors raise the activity of adrenergic and lower the activity of M-cholinergic structures participating in the formation of the functional system of pain reactions. An opposite effect can be accomplished through the medium of the T-serotonin receptors.
D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000502:physiology; D002540:Cerebral Cortex / Q000187:drug effects; D003791:Dental Pulp Test; D004305:Dose-Response Relationship, Drug; D005071:Evoked Potentials / Q000187:drug effects; D007180:Incisor; D007211:Indoles / Q000494:pharmacology; D008238:Lysergic Acid Diethylamide / Q000494:pharmacology; D009020:Morphine / Q000494:pharmacology; D011817:Rabbits; D011985:Receptors, Serotonin / Q000187:drug effects; D012701:Serotonin / Q000494:pharmacology*
D007211:Indoles; D011985:Receptors, Serotonin; D012701:Serotonin; D009020:Morphine; D008238:Lysergic Acid Diethylamide
Vliianie serotoninergicheskikh veshchestv na potentsialy mozga, vyzvannye razdrazheniem pul'py zuba.