Determinants of baroreflex sensitivity in man.
To determine the relationship of BRS to age, ACI, TPRI, and MBP, 61 male subjects, 19 to 65 years of age, whose MBP ranged from 77 to 134 mm Hg, were investigated. Partial correlative analysis was used to hold individual variables constant so that the effect of each on a given BRS relationship could be observed. An independent and significant relationship was observed between BRS and age; BRS and ACI correlated significantly through the influence of age, TPRI, and MBP; BRS and TPRI did not correlate; a significant BRS-MBP relationship existed through the influence of ACI. It was concluded that TPRI was not directly related to BRS and that the relationship of MBP to BRS was dependent on the influence of ACI whereas age was independently related to BRS.
D000328:Adult; D000368:Aged; D000375:Aging; D001158:Arteries / Q000502:physiology* / Q000503:physiopathology; D001794:Blood Pressure; D003187:Compliance; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011311:Pressoreceptors / Q000502:physiology* / Q000503:physiopathology; D012018:Reflex / Q000502:physiology*; D014655:Vascular Resistance