[Microphotometric study of the activity of oxidative enzymes in the endometrial epithelium of rats following ovariectomy and administration of testosterone propionate].
A method of comparative microphotometry was applied to the study of the oxidative enzymes in the epithelial lining of the uterine cavity and the glandular epithelium of the ovariectomized rats during the climacteric disturbances. There was an increase in the activity of lactic dehydrogenase (LDH) and glucose-6-phosphoric dehydrogenase (G-6-PDH) and a fall of the succinic dehydrogenase (SDH) and NAD- and NADP-diaphorases activity in the cells of the epithelial lining the uterine cavity. The glandular epithelium displayed an elevation of the LDH activity and a sharp fall of the SDH, NAD- and NADP-disphorases activity. Administration of testosterone-propionate caused an marked elevation of the activity of the oxidative enzymes in the epithelium of the rat endometrium in comparison with level of their activity in control animals and rats given no hormone.
D000818:Animals; D002369:Castration; D002979:Climacteric; D008058:Dihydrolipoamide Dehydrogenase / Q000378:metabolism; D004717:Endometrium / Q000201:enzymology*; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006651:Histocytochemistry; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D010088:Oxidoreductases / Q000378:metabolism*; D010783:Photometry; D051381:Rats; D013385:Succinate Dehydrogenase / Q000378:metabolism; D013739:Testosterone / Q000494:pharmacology*
D013739:Testosterone; D010088:Oxidoreductases; D007770:L-Lactate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D013385:Succinate Dehydrogenase; D008058:Dihydrolipoamide Dehydrogenase
Mikrofotometricheskoe issledovanie aktivnosti okislitel'nykh fermentov v épitelii éndometriia krys posle ovariéktomii i vvedeniia testosterona propionata.