Malacoplakia of the kidney: apparent improvement following medical management.
Malacoplakia of the kidney is a rare histopathologic entity of unknown etiology. Patients may present with a renal mass or with urinary tract infection. The prognosis has been uniformly poor excepting in those patients with unilateral involvement treated by nephrectomy. A 31 year old woman presented with acute renal failure and pyelonephritis. Renal biopsy revealed an interstitial infiltrate of large histiocytic cells with intracytoplasmic PAS-positive granules and calcospherules, findings consistent with malacoplakia. Following antibiotic treatment and dialysis, the patient has had a gradual improvement in renal function.
D058186:Acute Kidney Injury / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D000328:Adult; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D008287:Malacoplakia / Q000150:complications / Q000473:pathology / Q000628:therapy*; D010530:Peritoneal Dialysis
D005839:Gentamicins