[Preliminary experiences with the use of cimetidine in the treatment of acute hemorrhages in the upper gastrointestinal tract].
On the basis of favorable results recently reported in literature with cimetidine in the prevention and therapy of upper gastrointestinal haemorrhages, the Authors have treated a patient with severe haemorrhage from acute gastric ulcer arised after jejunum-ileal massive resection for mesenteric infarction. Result was very good, with stop of haemorrhage and quickly healing of the lesion. This clinical report is of interest particularly in view of high mortality of postoperative haemorrhagic acute gastropaties with therapeutic means, medical or surgical, just now available. At last the particular physiopathological aspects of the case suggested some considerations about mechanisms of action of the Cimetidine.
D000368:Aged; D002927:Cimetidine / Q000627:therapeutic use*; D005260:Female; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D008641:Mesenteric Vascular Occlusion / Q000601:surgery; D010438:Peptic Ulcer Hemorrhage / Q000188:drug therapy*; D011183:Postoperative Complications / Q000188:drug therapy; D013276:Stomach Ulcer / Q000150:complications*
D006146:Guanidines; D002927:Cimetidine
Prime esperienze sull'impiego della cimetidina nel trattamento delle emorragie acute nel tratto gastroenterico superiore.