The structure of tumours derived from mouse submandibular gland epithelium transformed in vitro.
The morphology and ultrastructure of 48 primary tumours established from 5 cell lines of adult mouse salivary gland epithelial cells transformed in vitro are described. Tumours from 4 of the cells lines were adenocarcinomas with a wide range of structural variation, and resembled human salivary gland carcinomas. The fifth cell line produced tumours with carcinomatous and sarcomatous elements.
D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D004847:Epithelial Cells; D051379:Mice; D008854:Microscopy, Electron; D012468:Salivary Gland Neoplasms / Q000648:ultrastructure*; D013363:Submandibular Gland / Q000648:ultrastructure*