[Melanocytes in epiloia; ultrastructural aspects (about 7 cases) (author's transl)].
Hypopigmented macules of epiloia have been studied by photonic and electron microscopy in 7 cases. The number of melanocytes was not decreased but these cells were hypotrophic and had a low tyrosinae activity. The melanosomes were smaller in size and their maturation rate was greatly reduced; many abnormal round and granular melanosomes, phaeomelanosome-like, were observed. In one case, such abnormal melanocytes were also occasionally found in normally pigmented control skin.
D000293:Adolescent; D000328:Adult; D002452:Cell Count; D002648:Child; D003937:Diagnosis, Differential; D004817:Epidermis / Q000648:ultrastructure; D004827:Epilepsy / Q000473:pathology; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000473:pathology; D008297:Male; D008544:Melanocytes / Q000648:ultrastructure; D012867:Skin / Q000648:ultrastructure*; D014402:Tuberous Sclerosis / Q000473:pathology*
les mélanocytes dans l'épiloïa; aspects ultrastructuraux (a propos de 7 cas).