The effects of mercurial poisoning on the vestibular system.
The sensory epithelium with adjacent nerve endings and the secretory epithelium may both become damaged following mercury chloride intoxication. Peripheral myelinated nerve fibres in the crista ampullaris showed signs of degeneration following chronic poisonins. Ultrastructural alterations of the vestibular hair cells initially occurred in animals free from clinical signs of intoxication. The sensory epithelium and occasionally the secretory cells were affected before signs of ultrastructural damage could be detected in the myelinated nerves.
D000818:Animals; D003051:Cochlea / Q000473:pathology / Q000648:ultrastructure; D004848:Epithelium / Q000473:pathology; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000473:pathology / Q000648:ultrastructure; D007759:Labyrinth Diseases / Q000139:chemically induced* / Q000473:pathology; D008630:Mercury Poisoning / Q000473:pathology*; D009410:Nerve Degeneration; D009925:Organ of Corti / Q000473:pathology; D012665:Semicircular Canals / Q000473:pathology; D011984:Sensory Receptor Cells / Q000473:pathology; D014725:Vestibular Nerve / Q000473:pathology / Q000648:ultrastructure