[Acute drug-induced agranulocytosis: comparison between openward treatment and antimicrobial decontamination in a plastic isolation bed system (retrospective study of 30 cases) (author's transl)].
Thirty patients with severe drug-induced agranulocytosis were admitted to the Ulm University Hospital between January, 1968 and October, 1976. All of 13 already infected patients treated with antimicrobial decontamination in a plastic isolation bed system survived. But nine of 17 patients treated in the open ward died. The cases were not randomised and there was a difference in age between the two groups, but nevertheless the results suggest that antimicrobial decontamination and isolation is superior to treatment in an open ward.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced / Q000150:complications / Q000628:therapy*; D001424:Bacterial Infections / Q000188:drug therapy; D001803:Blood Transfusion; D002228:Carbenicillin / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D005860:Germany, West; D006098:Granulocytes / Q000637:transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D010357:Patient Isolators; D012189:Retrospective Studies
D005839:Gentamicins; D002228:Carbenicillin
Akute arzneimittelinduzierte Agranulozytose. Vergleich zwischen herkömmlicher Krankenhausbehandlung und antimikrobieller Dekontamination im Plastikisolierbettsystem. Eine retrospektive Studie über 30 beobachtete Fälle.