Quadrone, a new antitumor substance produced by Aspergillus terreus. Production, isolation and properties.
A new antitumor compound named quadrone was isolated from the culture broth of Aspergillus terreus NRRL 11,156. Quadrone was active against KB cells in vitro, but died not possess antimicrobial activity.
D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification / Q000494:pharmacology; D001230:Aspergillus / Q000378:metabolism*; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D005285:Fermentation
D000903:Antibiotics, Antineoplastic