L-dopa and oligozoospermia.
A clinical investigation of L-Dopa on idiopathic oligozoospermia is carried out. Thirty nine male oligozoospermic patients with primary sterility were divided in two groups. The first group of 25 patients was treated with 500 mg a day during two months. The second group of 14 patients received 750 mg a day for the same time. In the first group we find 14 improvements, 9 at the first month and 5 at the second month. In the second group 8 improvements were observed, 5 in the first month and 3 in the second months. It would seem that L-Dopa has a stimulatory effect on spermatogenesis possibly through hypophysis when it is administered at these dosis and for these periods of time, and it was also observed similar results for longer terms of treatment.
D000328:Adult; D004341:Drug Evaluation; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D009845:Oligospermia / Q000188:drug therapy*; D013091:Spermatogenesis / Q000187:drug effects; D013997:Time Factors
D007980:Levodopa