[The stratified tuberculoma caused by Mycobacterium kansasii with cavitation (author's transl)].
Report on a 39 years old female textile worker with an acute cavity. M. kansasii was repeatedly isolated by cultivation from the sputum. The patient became negative by treatment with INH, SM, PAS, Ethionamide, but the cavity persisted. Therefore seven months after the onset of the disease the left upper lobe was resected. A colliquative Stratified tuberculoma and some lesions of caseated bronchitis and peribronchitis were found in the neigh bourhood. Clusters and microcolonies of M. kansasii could be observed as well in the wall of the cavity as in the centre of caseated bronchial lesions. The mycobacteria had a characteristic shabe of long segmentated rods. All about the microcolonies situated in the lumina of small bronchi and bronchioli caseated lesions were present, surrounded by specific granular tissue consisting of epithelial cells, some Langhans giant cells, lymphocytes and fibrocytes. The alterations caused by M. kansasii did not differ from those lesions caused by M. tuberculosis (human.) formerly described as stratified tuberculoma and caseated bronchial lesions with mycobacteria centrally located.
D000328:Adult; D005260:Female; D006801:Humans; D008168:Lung / Q000382:microbiology / Q000601:surgery; D009161:Mycobacterium / Q000302:isolation & purification*; D014375:Tuberculoma / Q000382:microbiology / Q000473:pathology* / Q000601:surgery
Das durch Mycobacterium kansasii hervorgerufene, geschichtete Tuberkulom mit Zerfallshöhle.