[Effect of dehydration on lipid metabolism].
Control of 25 sportsmen-wrestlers determined that accelerated loss in weight leads to a significant increase of ketone bodies evacuation with urine. The loss in weight for a 10-11 days period before a competition results in a less pronounced hyperketonuria. In experiment on rats it is shown that 48 and 98 hour hyperthermia and dehydration lead to the inhibition of the glucose-6-phosphate dehydrogenase activity in the liver. The mentioned permits supposing that under indicated conditions the inhibition of fat acid synthesis caused by NADPH2 and an increase of ketone bodies and cholesterol synthesis are observed.
D000818:Animals; D001835:Body Weight; D002784:Cholesterol / Q000096:biosynthesis; D003681:Dehydration / Q000378:metabolism*; D064429:Fatty Acid Synthases / Q000378:metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006801:Humans; D007657:Ketone Bodies / Q000378:metabolism / Q000652:urine; D050356:Lipid Metabolism; D008099:Liver / Q000201:enzymology; D008297:Male; D051381:Rats; D013177:Sports; D013178:Sports Medicine; D014952:Wrestling
D007657:Ketone Bodies; D002784:Cholesterol; D005954:Glucosephosphate Dehydrogenase; D064429:Fatty Acid Synthases
K voprosu o vliianii degidratatsii na lipidnyĭ obmen.