Micromeasurement of plasma salicylate in arthritic children.
A micromethod has been developed for determination of plasma salicylate. Frequent determinations of plasma salicylate levels in children with juvenile rheumatoid arthritis may be expected to provide greater therapeutic efficacy with reduced incidence of aspirin toxicity and consequently less need for use of secondary, more toxic, agents.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000097:blood* / Q000188:drug therapy; D001800:Blood Specimen Collection / Q000379:methods*; D002648:Child; D004347:Drug Interactions; D006801:Humans; D012459:Salicylates / Q000097:blood* / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D012459:Salicylates