Linkage disequilibrium in Bougainville Island.
Linkage disequilibria are estimated for three 2-locus systems in 18 samples from Bougainville Island, Solomon Islands. The systems are haptoglobin, acid phosphatase and MN blood group. The disequilibria are estimated two ways: by maximum likelihood (ML) and by the covariance between the non-alleles. Though seven of the 52 ML estimates are statistically different than zero, none of the covariance estimates are significant. We conclude that because linkage disequilibrium for loosely linked loci is a small quantity and because the sample sizes for most populations studied by anthropologists are small, linkage disequilibrium will not be a useful parameter for the study of natural selection in these populations.
D000135:Acid Phosphatase / Q000235:genetics; D000483:Alleles; D001699:Biometry / Q000379:methods; D044383:Black People; D008040:Genetic Linkage; D014644:Genetic Variation; D006242:Haptoglobins / Q000235:genetics; D006801:Humans; D008951:MNSs Blood-Group System / Q000235:genetics; D009512:New Guinea
D006242:Haptoglobins; D008951:MNSs Blood-Group System; D000135:Acid Phosphatase