Long-term prognosis of patients with central cerebral ventricular enlargement. A fifth follow-up study of 100 patients with a 3rd ventricle measuring 12 mm or more in width.
One hundred patients with a 3rd ventricle width of 12 mm or more were examined for the fifth time in 1976 after an average observation period of 20.8 years. On first admission, a predominant aetiological factor was found in 27 cases. Two patients had air-encephalogrophical findings indicating normal pressure hydrocephalus. One of these had a shunt operation, however, without improvement. Seventy-one patients had died, 7 patients were in need of care and supervision, 11 patients were unable to work, the remaining 11 were able to work to some extent. The group studied had a significantly increased mortality rate. The causes of death were divided into three groups: 1. Probably related to the underlying brain disorder; 2. Related to those in an average Norwegian population; and 3. Minor disorder usually not leading to death. The following factors indicated a poor long-term prognosis: 1. Serious associated disease; 2. A relatively high age; 3. Associated cardiovascular disease; 4. Marked degree of ventricular enlargement; 5. Marked enlargement of the temporal horns; 6. Many and/or marked neurological signs; and 7. Prognosis intellectual deterioration.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001927:Brain Diseases / Q000150:complications / Q000401:mortality*; D002318:Cardiovascular Diseases / Q000150:complications / Q000401:mortality; D002552:Cerebral Ventricles; D002648:Child; D006259:Craniocerebral Trauma / Q000150:complications / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006850:Hydrocephalus, Normal Pressure; D006984:Hypertrophy; D008297:Male; D008875:Middle Aged; D011011:Pneumoencephalography; D011379:Prognosis; D012737:Sex Factors; D013997:Time Factors; D014938:Work Capacity Evaluation