[Effects of isoprenaline bronchodilation on the partial pressure of oxygen in various clinical forms of bronchial asthma].
Blood gas disturbances noted in recent asthma were fully corrected with 1% isoprenalin aerosol, though changes in PaO2 were usually unobtainable in patients with chronic bronchopneumopathic obstruction. Simultaneous administration of 70% hyperoxygenated air via an intermittent positive pressure respirator led to a significant increase in this parameter, but was rarely followed by normalisation of the blood gas picture. It is considered that this finding is attributable to increased anatomical shunt at the alveolocapillary level.
D000328:Adult; D000368:Aged; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007545:Isoproterenol / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*; D010313:Partial Pressure; D014692:Ventilation-Perfusion Ratio / Q000187:drug effects; D014797:Vital Capacity / Q000187:drug effects
D007545:Isoproterenol; D010100:Oxygen
Effetti della broncodilatazione isoprenalinica sulla pressione parziale di ossigeno del sangue nelle varie forme cliniche di asma bronchiale.