Trisomy 10p due to t(5;10)(p15;p11) segregating in a large sibship.
A family is reported with a segregating t(5;10)(p15;p11) translocation resulting in a child carrying trisomy 10p. The clinical findings of the patient are compared with trisomy 10p and the Cri-du-Chat syndrome.
D000015:Abnormalities, Multiple / Q000235:genetics; D001344:Autopsy; D002906:Chromosomes, Human, 6-12 and X; D003410:Cri-du-Chat Syndrome / Q000235:genetics; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D010375:Pedigree; D014178:Translocation, Genetic; D014314:Trisomy