[Study of the multiple puncture method in smallpox vaccination of children].
In this work the multiple puncture method (in 76 cases) was compared with the scarification method--2 clinear cuts (in 70 cases). "Vaccine take" of the vaccines demonstrated a statistically significant difference: by the first method the percentage of personal "vaccine take" was 98.7, and by the second--86.4. The multiple puncture method produced a less pronounced local and general reaction. Immunological efficacy of the multiple puncture method (evaluated by hemagglutination inhibition test and neutralization test in the tissue culture) was quite satisfactory and failed to differ from such in vaccination by scarification.
D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D011677:Punctures / Q000379:methods*; D012899:Smallpox / Q000276:immunology; D012900:Smallpox Vaccine / Q000008:administration & dosage*; D014611:Vaccination / Q000379:methods*
D012900:Smallpox Vaccine
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