Pathological and biochemical observations on subclinical cases of fatty liver-haemorrhagic syndrome in the fowl.
A high incidence of subclinical fatty liver-haemorrhagic syndrome (FLHS) was found in three flocks of laying hens in which deaths from FLHS had occurred. There was so significant difference between the affected hens and the remainder of the block in egg production or quality, but the former were more obese and had higher concentrations of lipids in their livers, suggesting a pathogenic relationship between hepatic steatosis and haemorrhage. Soluble protein tended to accumulate with the fat in the livers. Reticulolysis had occurred in over half the haemorrhagic livers examined. Histological examination and DNA estimations provided no evidence of generalised hyperplasia. From the composition of the liver lipids it was concluded that the steatosis resulted mainly from an increase in lipogenesis from dietary carbohydrate. Lipid levels in the plasma were weakly correlated with those in the liver. No change was detected in the plasma protein pattern.
D000818:Animals; D002645:Chickens; D005234:Fatty Liver / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006470:Hemorrhage / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D008099:Liver / Q000473:pathology; D011201:Poultry Diseases / Q000378:metabolism / Q000473:pathology; D013577:Syndrome / Q000662:veterinary