[Clinical application of extracellular fluid measurement using 35S-sodium sulfate (author's transl)].
ECF (extracellular fluid volume) was measured by 35S-sodium sulfate and the same time value of PV (plasma volume) was determined by 131I-RISA in each subject. In normal ECF was an average of 181 ml/kg, 6.21 l/m2 and PV was 49.1 ml/kg, 1.69 l/m2. Both values of ECF and PV in essential hypertension were almost the same as those in normal. In congestive heart failure ECF was 232 ml/kg, 7.51 l/m2 and PV was 55.8 ml/kg, 1.80 l/m2. In the patients with ascites or edema, ECF was 256 ml/kg, 8.69 l/m2 and PV was 53.0 ml/kg, 1.79 l/m2. The results of the measurement by the two compounds also corresponded to the conditions of the patients who showed electrolytes disorders (ACTH deficiency, SIADH) and was improved by treatment.
D000328:Adult; D001201:Ascites / Q000503:physiopathology; D004487:Edema / Q000503:physiopathology; D005110:Extracellular Space / Q000032:analysis*; D006333:Heart Failure / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D010953:Plasma Volume; D012711:Serum Albumin, Radio-Iodinated; D013431:Sulfates; D013462:Sulfur Radioisotopes; D014883:Water-Electrolyte Imbalance / Q000503:physiopathology
D007457:Iodine Radioisotopes; D012711:Serum Albumin, Radio-Iodinated; D013431:Sulfates; D013462:Sulfur Radioisotopes