[Differences of capacity of human erythrocytes of newborn infants and adults and trypsin-treated erythrocytes to bind rubella virus hemagglutinin].
Rubella virus hemagglutinating (HA) antigen shows different titers against non treated, trypsin-modified and cord blood human erythrocytes. Trypsin-modified erythrocytes give titers eleven fold higher, and cord blood red cells sixteen fold higher than those seen with the non treated cells. These differences in sensitivity agree with a different ability to bind HA antigen: with an excess of antigen cord blood erythrocytes bind two, and trypsin-modified erythrocytes three times as much antigen was bound by non treated cells. The amount of bound antigen shows little or no dependence on 4 degrees or 37 degrees C temperatures.
D000328:Adult; D000367:Age Factors; D001666:Binding Sites, Antibody; D004912:Erythrocytes / Q000276:immunology*; D005312:Fetal Blood; D006389:Hemagglutinins, Viral; D006801:Humans; D007231:Infant, Newborn; D012412:Rubella virus / Q000276:immunology*; D014357:Trypsin / Q000494:pharmacology
D006389:Hemagglutinins, Viral; D014357:Trypsin
Differenze tra la capacita delle emazie umane di neonato, di adulto e tripsinizzate di legare l'emagglutinina del virus della rosolia.