Histopathological changes in experimental drug-induced collagen disease-like syndrome.
Prolonged administration of 1-hydrazinophthalazine (hydralazine) to guinea pigs stimulated the development of collagen disease-like syndrome. Inflammatory changes were found in the heart, kidneys and skin.
D000818:Animals; D001808:Blood Vessels / Q000473:pathology; D003095:Collagen Diseases / Q000139:chemically induced / Q000473:pathology*; D003238:Connective Tissue / Q000473:pathology; D006168:Guinea Pigs; D006830:Hydralazine; D007249:Inflammation / Q000209:etiology; D007668:Kidney / Q000473:pathology; D008297:Male; D009206:Myocardium / Q000473:pathology*; D012867:Skin / Q000473:pathology
D006830:Hydralazine