[Rat hemoglobulin normally and under hypoxic action].
The hemoglobin (Hb) pattern of adult and newborn rats, as well as of chronically hypoxic rats was studied by the method of electrophoresis on starch gel. It was shown that the experimental animals were Hb polymorphic. The slow-moving bands of Hb pattern were more pronounced and the alkali resistance was greater in newborns as compared to adults. In the course of adaptation to hypoxia there occur some shifts in the quantitative ration of the fractions in favour of one of the slow-moving fractions; however, this phenomenon does not follow the enhancement of the fetal Hb synthesis, as it is generally accepted. There were no changes in the electrophoretic mobility of the fractions. Mildness of the changes revealed under hypoxic conditions suggests that the Hb synthesis in rats is rather stable.
D000222:Adaptation, Physiological; D000818:Animals; D000831:Animals, Newborn / Q000097:blood; D004592:Electrophoresis, Starch Gel; D006454:Hemoglobins / Q000032:analysis*; D000860:Hypoxia / Q000097:blood*; D008297:Male; D011110:Polymorphism, Genetic; D051381:Rats; D013997:Time Factors
D006454:Hemoglobins
Gemoglobulin krys v norme i pri deĭstvii gipoksii.