Diagnostic and therapeutic problems in Cushing's syndrome. Series of 7 cases.
A series of 7 patients (all females) with Cushing's syndrome are presented. The syndrome was due to an adenoma of the cortex in 4 cases, to a carcinoma in 1 and to bilateral adrenal hyperplasia in another. In the 7th patient the cortical hyperplasia was due to a bronchogenic carcinoma (ectopic production of ACTH). Surgery was performed in all patients except 1. In 5 patients (adenoma, carcinoma) the diseased adrenal was removed. In 1 patient a left total and a right subtotal adrenalectomy were performed. Out of those 7 patients 4 survived and 3 died. 1 died a few hours after surgery, another 3 months after operation and the last one was never operated on.
D000236:Adenoma / Q000175:diagnosis; D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis; D000311:Adrenal Glands / Q000473:pathology; D000315:Adrenalectomy; D000328:Adult; D002277:Carcinoma / Q000175:diagnosis; D003480:Cushing Syndrome / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008875:Middle Aged