The importance of plasma lipid, glucose, insulin and fibrinogen in femoropopliteal surgery.
Fasting blood levels of cholesterol, triglyceride, glucose insulin and fibrinogen were measured preoperatively in 44 patients who had reconstructive operations for occlusive disease in the femoral and popliteal arteries. Comparison of these preoperative biochemical measurements with the results of surgery over a 4-year period indicated that failure was associated with significantly higher mean preoperative levels of both glucose (P less than 0.01) and fibrinogen (P less than 0.01). High fasting blood glucose was associated with early failure (occlusion between 3 and 12 months) and high plasma fibronogen was associated with late failure (occlusion between 1 and 4 years). The results of operation were not influenced significantly by preoperative blood levels of cholesterol, triglyceride or insulin.
D000328:Adult; D000368:Aged; D001157:Arterial Occlusive Diseases / Q000097:blood / Q000601:surgery; D001786:Blood Glucose / Q000032:analysis*; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D005340:Fibrinogen / Q000032:analysis*; D005500:Follow-Up Studies; D006801:Humans; D007328:Insulin / Q000097:blood*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000601:surgery*; D012008:Recurrence
D001786:Blood Glucose; D007328:Insulin; D008055:Lipids; D005340:Fibrinogen