[Occurrence of induced vitamin-dependent mutants of Yersinia pestis].
Vitamin-dependent mutants were isolated from Yersinia pestis after the treatment with supermutagens. From 13 mutants obtained 10 appeared to be unstable. The stable vitamin-dependent mutants were revealed with the frequency of 2.5.10(-11) divided by 4.9.10(-11) by the indirect method of selection and 5.10(-7) by the use of Davis's method. The frequency of amino acid and nitrogen base dependent auxotroph isolation was significantly higher than that of the vitamin-dependent mutants.
D008770:Methylnitrosourea / Q000494:pharmacology; D009154:Mutation; D009604:Nitrosoguanidines / Q000494:pharmacology; D014466:Ultraviolet Rays; D014815:Vitamins; D015010:Yersinia pestis / Q000187:drug effects / Q000235:genetics* / Q000528:radiation effects
D009604:Nitrosoguanidines; D014815:Vitamins; D008770:Methylnitrosourea
Vstrechaemost' indutsirovannykh vitaminzavisimykh mutantov Jersinia pestis.