Levels of homocytotropic antibody in hereditarily asplenic, splenectomized and normal mice.
No significant differences were detected in circulating levels of IgE or IgG1 in hereditarily asplenic (Dh/+) or splenectomized mice compared to normal controls (+/+). These findings suggest that the spleen plays a minor role in the regulation of IgG1 and IgE production in this mouse line.
D000818:Animals; D000918:Antibody Specificity; D007111:Immunity, Cellular; D007073:Immunoglobulin E / Q000096:biosynthesis; D007074:Immunoglobulin G / Q000096:biosynthesis; D007518:Isoantibodies / Q000032:analysis*; D051379:Mice; D010047:Ovalbumin / Q000276:immunology; D010323:Passive Cutaneous Anaphylaxis; D013154:Spleen / Q000002:abnormalities*; D013156:Splenectomy
D007074:Immunoglobulin G; D007518:Isoantibodies; D007073:Immunoglobulin E; D010047:Ovalbumin