Differential effect of pentazocine on primary cortical evoked potentials elicited by stimulation of the trigeminal tract and spinal cord pathways.
The influence of pentazocine on primary cortical evoked potentials was studied in guinea pigs under pentobarbital anesthesia. Pentazocine (10 mg/kg, i.v.) increased the latency time of evoked responses to posterior limb stimulation, more than that of response to lip stimulation. This result suggests that pentazocine decreases the velocity of nervous conduction.
D000818:Animals; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000187:drug effects*; D005121:Extremities / Q000502:physiology; D006168:Guinea Pigs; D008046:Lip / Q000502:physiology; D010423:Pentazocine / Q000494:pharmacology*; D013116:Spinal Cord / Q000502:physiology*; D013997:Time Factors; D014276:Trigeminal Nerve / Q000502:physiology*
D010423:Pentazocine