Intrauterine fetal transfusion, 1965-1976, with an assessment of the surviving children.
The need for IUT in the management of Rh hemolytic disease is likely to continue in the foreseeable future. Recent reports have been skeptical about the success of this procedure and the quality of the surviving infants. Of 84 fetuses who received 134 IUT's, over all, 35.7 per cent survived; 48.3 per cent of the nonhydropic group survived. Fifteen of the 23 survivors between 3 and 11 years of age received intellectual, academic, behavioral, health, and developmental evaluations. When compared to sibling and high-risk control groups, the study children showed no significant differences in intelligence quotients, arithmetic achievements, or reading achievements; their school performance is acceptable and none is presenting significant behavioral problems. Except for an excessive number of umbilical and inguinal hernias, there were no physical abnormalities that could be directly related to IUT.
D000649:Amniocentesis; D001805:Blood Transfusion, Intrauterine; D002648:Child; D002652:Child Behavior; D002657:Child Development; D002675:Child, Preschool; D036861:Delivery, Obstetric; D004487:Edema / Q000453:epidemiology; D004899:Erythroblastosis, Fetal / Q000401:mortality / Q000628:therapy*; D005260:Female; D005313:Fetal Death; D005315:Fetal Diseases / Q000453:epidemiology; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007360:Intelligence; D011247:Pregnancy; D012189:Retrospective Studies