Methyl cholanthrene and cadmium induced changes in rat prostate.
Cadmium workers have been thought to be more likely to develop prostatic cancer. The present study compares the effects of cadmium on rat prostate as compared with a known carcinogen, 20 methyl cholanthrene. The various histological effects produced are discussed. Possibly the most important aspect is the stratification and primitive clear cells found in rat prostatic acini in cadmium injected rats.
D000818:Animals; D002104:Cadmium / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D008748:Methylcholanthrene / Q000008:administration & dosage; D011467:Prostate / Q000187:drug effects* / Q000473:pathology; D011471:Prostatic Neoplasms / Q000139:chemically induced; D051381:Rats
D002104:Cadmium; D008748:Methylcholanthrene