[On moleculare biology of ageing. 13th communication. Proteins, age (author's transl)].
Qualitative changes of proteins in old age are described in relation to the hypothesis of Orgel. A faulty protein structure may be caused by 1. faults in the genetic informations 2. faults of the transcription 3. faults in the translation 4. posttranslational changes.
D000375:Aging; D000818:Animals; D002478:Cells, Cultured; D005347:Fibroblasts / Q000201:enzymology; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006801:Humans; D008099:Liver / Q000201:enzymology; D051379:Mice; D008967:Molecular Biology; D010452:Peptide Biosynthesis; D014176:Protein Biosynthesis; D014158:Transcription, Genetic
D005954:Glucosephosphate Dehydrogenase
Zur Molekularbiologie des Alterns. 13. Mitteilung: Qualitative Veränderung der Proteine im Alter.