[Progress in diagnosis of gastric function: gastric secretory analysis, intragastric titration, endocrine provocation tests (author's transl)].
Diagnostic procedures for the measurement of gastric acid secretion and for the differention between several types of hypergastrinemia have been improved during the last years. An intravenous dose-response curve with increasing doses of pentagastrin resulted in 30% higher MAO compared to subcutaneously administered pentagastrin (6 microgram/kg body weight). Food-stimulated gastric acid secretions can be measured by intragastric titration; this method is used mainly in clinical-physiological studies. The different forms of hypergastrinemia may be differentiated by 3 provocation tests: calciuminfusion, secretintest, glucagontest. In atypical cases of Zollinger-Ellison-Syndrome it may be necessary to perform all 3 tests.
D002118:Calcium; D004305:Dose-Response Relationship, Drug; D005750:Gastric Juice / Q000378:metabolism*; D005755:Gastrins / Q000097:blood; D005934:Glucagon; D006801:Humans; D010418:Pentagastrin; D010437:Peptic Ulcer / Q000175:diagnosis; D012633:Secretin; D013272:Stomach Diseases / Q000175:diagnosis*; D015043:Zollinger-Ellison Syndrome / Q000175:diagnosis
D005755:Gastrins; D012633:Secretin; D005934:Glucagon; D010418:Pentagastrin; D002118:Calcium
Methodischer Fortschritt in der Funktionsdiagnostik des Magens: Magensekretionsanalyse, intragastrale Titration, endokrine Provokationstests.