title: [Antibiotic action on the embryonic development of the fetuses of amphibians].
abstract: The effect on the embrionic development of Tr. cristatus of 16 antibiotics (keflin, penicillin, benzazillin, ampicillin, nystatin, kanamycin, streptomycin, novobiocin, brunomycin, erythran, oleandomycin, tetracyclin, chlornytromycin, gentamycin, rimactan, and capreomycin) administered in 3 concentrations was studied. It was established that except kanamycin, keflin and rimactan all the rest damage the embryonic development showing certain phase specifity. Gastrulation turned to be the most sensitive embryonic period.
mesh_terms: D000663:Amphibians / Q000196:embryology*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D004625:Embryo, Nonmammalian / Q000187:drug effects*; D005260:Female; D011247:Pregnancy; D013997:Time Factors; D014319:Triturus / Q000196:embryology
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Izsledvane vuzdeĭstvieto na antibiotitsite vurkhu embrionalnoto razvitie na zarodishi ot zemnovodni.