Depletion of cellular glycogen during the early logarithmic growth phase of human fibroblasts.
Human diploid fibroblasts deplete 50% of their cellular glycogen by day 4 after subcultivation in 100 mg% glucose medium. The glycogen content increases again as the cells approach confluency. Growth of cells in low glucose medium results in rapid glycogen depletion and indicates that stored glycogen has a limited potential as an energy source.
D002478:Cells, Cultured; D003470:Culture Media; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism*; D005947:Glucose / Q000494:pharmacology; D006003:Glycogen / Q000378:metabolism*; D006801:Humans; D011506:Proteins / Q000378:metabolism; D013997:Time Factors
D003470:Culture Media; D011506:Proteins; D006003:Glycogen; D005947:Glucose