Effects of quinone derivatives on an experimental tumor.
In continuation of studies on the activity of known solid tumor inhibitors, four acetylated glycosyl derivatives of 1,4-quinones were prepared and tested against Ehrlich ascitic tumor. All four compounds significantly inhibited growth of this neoplasm. UV, IR, and mass spectra are given for the three new synthetic quinone derivatives.
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000627:therapeutic use; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy; D051379:Mice; D011809:Quinones / Q000138:chemical synthesis* / Q000494:pharmacology / Q000627:therapeutic use
D000970:Antineoplastic Agents; D011809:Quinones