[Changes in erythrocyte membrane permeability after freezing with polyethylene oxide and glycerol].
Membrane ion permeability to sodium cations and phosphate anions, acid resistance and phospholipid composition were studied in erythrocytes frozen and thawed with 15% glycerol and 10% solution of polyethylene oxide 1500. An increase in membrane permeability to 22Na and HPO4(2-) against a background of reduction in phospholipids and total acid resistance was observed after rapid freezing-thawing and removing of cryoprotectants.
D002463:Cell Membrane Permeability / Q000187:drug effects*; D004910:Erythrocyte Membrane / Q000187:drug effects*; D004912:Erythrocytes / Q000187:drug effects*; D005615:Freezing; D005990:Glycerol / Q000494:pharmacology*; D006801:Humans; D010710:Phosphates / Q000378:metabolism; D010743:Phospholipids / Q000097:blood; D011095:Polyethylenes / Q000494:pharmacology*; D012964:Sodium / Q000378:metabolism
D010710:Phosphates; D010743:Phospholipids; D011095:Polyethylenes; D012964:Sodium; D005990:Glycerol
Izmenenie pronitsaemosti membran epitrotsitov posle zamorazhivaniia v prisutstvii polietilenoksida i glitserina.