Delayed hypersensitivity response to oxazolone in neonatally estrogenized mice.
Neonatal NMRI mice were treated with diethylstilbestrol (DES) fof the first 5 days after birth. At 6 and 9 months the same animals were tested for delayed hypersensitivity reaction using an ear test with oxazolone. The DES treated animals had a diminished response to oxazolone compared with controls.
D000818:Animals; D000831:Animals, Newborn; D004054:Diethylstilbestrol / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D006968:Hypersensitivity, Delayed; D007111:Immunity, Cellular / Q000187:drug effects; D051379:Mice; D010080:Oxazoles / Q000276:immunology*; D010081:Oxazolone / Q000276:immunology*; D012882:Skin Tests
D010080:Oxazoles; D010081:Oxazolone; D004054:Diethylstilbestrol