Lysosomal stability, superoxide dismutase and zinc deficiency in regenerating rat liver.
1. Lysosomal stability was slightly increased in regenerating livers from rats receiving a zinc-deficient (less than 0.5 mg/kg) diet for 10 d before surgery. 2. The activity of superoxide dismutase (EC 1.15.1.1) was significantly reduced in the same tissues. 3. The results do not support the view that increased lysosomal fragility represents a major biochemical consequence of nutritional Zn deficiency in animals.
D000818:Animals; D002462:Cell Membrane / Q000502:physiology; D005260:Female; D005966:Glucuronidase / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D008115:Liver Regeneration; D008247:Lysosomes / Q000201:enzymology*; D051381:Rats; D013482:Superoxide Dismutase / Q000378:metabolism*; D015032:Zinc / Q000172:deficiency*
D013482:Superoxide Dismutase; D005966:Glucuronidase; D015032:Zinc