title: Response to vincristine and Procarbazine of recurrent medulloblastomas. Report of 2 cases.
abstract: 2 cases of recurrent medulloblastomas are described who both responded to vincristine alone and in combination with procarbazine. The combination of vincristine and procarbazine is discussed and recommended for chemotherapy of medulloblastomas. The effectiveness of adjuvant chemotherapy after the primary treatment should be investigated.
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging; D001932:Brain Neoplasms / Q000188:drug therapy*; D002648:Child; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008527:Medulloblastoma / Q000188:drug therapy*; D009364:Neoplasm Recurrence, Local; D011344:Procarbazine / Q000627:therapeutic use*; D011877:Radionuclide Imaging; D014750:Vincristine / Q000627:therapeutic use*
chemical_list: D011344:Procarbazine; D014750:Vincristine