[Treatment of reactive stuporous states with L-DOPA].
The paper presents the results of L-dopa use for the treatment of patients with reactive stuporous states. The assumption concerning curability of these patients is based on the similarity of a number of their clinical and biochemical manifestations with an akynetic-rigid form of parkinsonism where L-dopa is very effective. From 25 patients with reactive psychoses 7 demonstrated recovery, 3 patients--significant improvement, 5 patients--improvement and 10 patients--absence of the effect. The drug is the most effective in the stuporous depth of psychomotor inhibition in persons with a monomorphic structure of stuporous syndromes, rather "frequent" depressive disorders and a decrease of a background level of dopamine excreation with urine. Use of L-dopa in schizophrenic stuporous states (5 patients) was ineffective.
D000328:Adult; D000928:Antidepressive Agents; D002395:Catecholamines / Q000652:urine; D003072:Cognition Disorders / Q000188:drug therapy*; D003244:Consciousness Disorders / Q000150:complications / Q000188:drug therapy* / Q000652:urine; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D008875:Middle Aged; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000652:urine; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy; D013577:Syndrome
D000928:Antidepressive Agents; D002395:Catecholamines; D007980:Levodopa
Lechenie reaktivnykh stuporoznykh sostoianiĭ preparatom L-DOFA.