title: [Enzyme values in the serum of newborn blood in relation to the course of parturition (author's transl)].
abstract: In 43 newborn, the enzyme activities of LDH, GOT, GLDH, and GPT in the umbilical cord blood, as well as 24 hours post partum was measured. Two groups were formed: 1. Newborn without decelerations during the course of parturition, and 2. Newborn with decelerations in the cardiotocogram. The oxygen partial pressure and the acid-base status in the umbilical cord blood, did not differ significantly in both groups. LDH, GOT and GLDH activities were significantly higher 24 hours post partum in the group of newborn with decelerations, than in the control group. The increase in GLDH by 75% was particularly remarkable. This GLDH increase seems to suggest an increased incidence of liver cell necroses, which must be interpreted as a result of the hypoxic conditions sub partu. A significant correlation between the magnitude of the deceleration areas and the extent of GLDH activities can be established. The correlation between duration of parturition and GLDH activity is likewise significant.
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D004798:Enzymes / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000201:enzymology*; D005969:Glutamate Dehydrogenase / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007743:Labor, Obstetric; D011247:Pregnancy
chemical_list: D004798:Enzymes; D007770:L-Lactate Dehydrogenase; D005969:Glutamate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
vernacular_title: Enzymwerte im Serum von Neugeborenenblut in Beziehung zum Geburtsverlauf.