title: Clotrimazole (Canesten) in the treatment of candidal balanitis in men. With incidental observations on diabetic candidal balanoposthitis.
abstract: Clotrimazole 1% (Canesten) cream was used in a trial comprising 138 men with candidal balanitis. Eighty-six (91%) out of 94 men were asymptomatic after seven days and 57 (98%) of 58 men were asymptomatic after three weeks' treatment. After seven days, Candida albicans could no longer be cultured from 86 (90%) of 96 men, nor from 55 (95%) of 58 men three weeks after treatment. Microscopical examination gave varying results. Fifteen (10.9%) of 138 men were found to have diabetes mellitus; this group was significantly older than the non-diabetics. It is concluded that treatment with clotrimazole for seven days is effective in the treatment of candidal balanitis.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001446:Balanitis / Q000188:drug therapy* / Q000209:etiology; D002177:Candidiasis / Q000150:complications / Q000188:drug therapy*; D003022:Clotrimazole / Q000627:therapeutic use*; D048909:Diabetes Complications; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
chemical_list: D007093:Imidazoles; D003022:Clotrimazole