Sympathetic nervous system activity in patients with subarachnoid hemorrhage.
In patients with subarachnoid hemorrhage there were increased concentrations of plasma epinephrine and norepinephrine when compared with those concentrations in a group of patients admitted to hospital with other illness. Reassessment after a variable period showed that in patients whose eventual clinical result was poor the plasma epinephrine and norepinephrine concentrations increased further while in those with a good result those concentrations showed a decline. No such changes were evident in plasma dopamine-beta-hydroxylase activities which were within normal range. In a sub-group of patients who had neurosurgery after admission for clipping an aneurysm, the post-operative changes of plasma epinephrine and norepinephrine concentrations were related to the clinical condition of the patients.
D000293:Adolescent; D000328:Adult; D000758:Anesthesia; D004299:Dopamine beta-Hydroxylase / Q000097:blood; D004837:Epinephrine / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D009638:Norepinephrine / Q000097:blood; D011182:Postoperative Care; D011183:Postoperative Complications / Q000097:blood; D013345:Subarachnoid Hemorrhage / Q000097:blood* / Q000601:surgery; D013564:Sympathetic Nervous System / Q000378:metabolism*; D013997:Time Factors
D004299:Dopamine beta-Hydroxylase; D009638:Norepinephrine; D004837:Epinephrine