title: Mechanism of coumarin action: significance of vitamin K epoxide reductase inhibition.
mesh_terms: D000818:Animals; D004351:Drug Resistance; D005971:Glutamates; D008025:Ligases / Q000378:metabolism; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors*; D008954:Models, Biological; D010084:Oxidation-Reduction; D011516:Prothrombin; D051381:Rats; D014812:Vitamin K; D014813:Vitamin K Deficiency / Q000201:enzymology*; D014859:Warfarin / Q000494:pharmacology*
chemical_list: D005971:Glutamates; D014812:Vitamin K; D014859:Warfarin; D011516:Prothrombin; D006899:Mixed Function Oxygenases; D008025:Ligases