[Immunological changes during the immediate postoperative period (author's transl)].
Postoperative variations in the different parameters of humoral and cellular immunity were studied in 18 adult patients in general surgery. Levels of immunoglobulins G (igG) fell and those of immunoglobulins M (igM) increased significantly. Lymphocytic proliferation under the influence of PHA showed a significant fall. Neither polynuclear function nor total complement activity were modified. Patients in whom the postoperative course was complicated by sepsis differed from the others by a lower activity of the lymphocyte transformation test and by a higher level of igG and igM on the day prior to surgery. In addition, deficiency in the lymphoblastic transformation test increased during the postoperative period, there was a further fall in IgG and IgM increased less in these patients than in those in whom the postoperative course was uncomplicated.
D000328:Adult; D000368:Aged; D003165:Complement System Proteins / Q000032:analysis*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis*; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D010587:Phagocytosis; D011183:Postoperative Complications; D013514:Surgical Procedures, Operative
D007136:Immunoglobulins; D003165:Complement System Proteins
Modifications immunitaires dans les suites opératoires immédiates.