[Course of experimental cardiac insufficiency under conditions of high altitude depending on the periods of adaptation].
The data characterizing the compensatory hyperfunction of the circulation and respiration with dosaged insufficiency of the mitral valve in animals, depending on the periods of adaptation to high-altitude are presented. Unadapted animals with insufficiency of the mitral valve had more serious disorders of hemodynamic and gaseous exchange accompanied by stasis in the lesser and greater circulation. 52.9% of the animals died during the first days after the formation of the mitral defect. In animals adapted to the high altitude hypoxia the process coursed with less pronounced disturbances of circulation and respiration; 28.6% of the animals died.
D000222:Adaptation, Physiological; D000531:Altitude; D000818:Animals; D004285:Dogs; D005260:Female; D006439:Hemodynamics; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D008944:Mitral Valve Insufficiency / Q000503:physiopathology*; D009200:Myocardial Contraction; D010101:Oxygen Consumption; D012119:Respiration
Techenie eksperimental'noĭ serdechnoĭ nedostatochnosti v usloviiakh vysokogor'ia v zavisimosti ot srokov adaptatsii.