Reversible modulation of the activities of both liver microsomal hydroxymethylglutaryl coenzyme A reductase and its inactivating enzyme. Evidence for regulation by phosphorylation-dephosphorylation.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D003600:Cytosol / Q000201:enzymology; D004789:Enzyme Activation; D006903:Hydroxymethylglutaryl CoA Reductases / Q000378:metabolism*; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008099:Liver / Q000201:enzymology; D008862:Microsomes, Liver / Q000201:enzymology*; D010750:Phosphoproteins / Q000378:metabolism; D010765:Phosphorylase Phosphatase / Q000378:metabolism; D011494:Protein Kinases / Q000378:metabolism; D051381:Rats
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D010750:Phosphoproteins; D000255:Adenosine Triphosphate; D006903:Hydroxymethylglutaryl CoA Reductases; D011494:Protein Kinases; D010765:Phosphorylase Phosphatase