title: [The anti-hypertensive effect of the diuretic etozolin. Results of a double-blind test].
abstract: In a double-blind study under strict, standardized hospital conditions, the antihypertensive effect of etozolin was evalulated in 100 patients with hypertension. 50 patients received the drug, 50 placebo. The study was carried out over 22 days (5 days without medication, 12 days therapy, 5 days follow-up). A significantly better reduction of systolic and diastolic blood pressure in the supine and upright positions was observed with etozolin as compared to the pre-period and the placebo group. There were only minor side-effects; in 4 patients, therapy had to be interrupted because of orthostatic complaints.
mesh_terms: D004232:Diuretics / Q000627:therapeutic use*; D004311:Double-Blind Method; D004341:Drug Evaluation; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D010880:Piperidines / Q000627:therapeutic use; D010919:Placebos; D013844:Thiazoles / Q000627:therapeutic use*
chemical_list: D004232:Diuretics; D010880:Piperidines; D010919:Placebos; D013844:Thiazoles; C015208:etozolin
vernacular_title: Zur antihypertensiven Wirkung des Diuretkums Etozolin. Ergebnisse einer Doppelblind-Prüfung.