Evidence for significant quantities of creatine kinase MM isoenzyme in human brain.
The isoenzymes of creatine kinase (ATP: creatine N-phosphotransferase, EC 2.7.3.2) in human brain were studied. Approx. 30% of total creatine kinase activity is due to the MM isoenzyme. The identity of this isoenzyme was confirmed by several techniques and shown not to be of mitochondrial origin.
D001921:Brain / Q000201:enzymology*; D003402:Creatine Kinase / Q000378:metabolism*; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D007700:Kinetics; D009132:Muscles / Q000201:enzymology; D009203:Myocardial Infarction / Q000201:enzymology; D014018:Tissue Distribution
D007527:Isoenzymes; D003402:Creatine Kinase