A numerical method to model excitable cells.
We have extended a fast, stable, and accurate method for the numerical solution of cable equations to include changes in geometry and membrane properties in order to model a single excitable cell realistically. In addition, by including the provision that the radius may be a function of distance along an axis, we have achieved a general and powerful method for simulating a cell with any number of branched processes, any or all of which may be nonuniform in diameter, and with no restriction on the branching pattern.
D000200:Action Potentials; D000818:Animals; D001369:Axons / Q000502:physiology*; D008433:Mathematics; D008564:Membrane Potentials; D008567:Membranes, Artificial; D008954:Models, Biological; D009186:Myelin Sheath / Q000502:physiology
D008567:Membranes, Artificial