The affinity of cytochrome P-450 for ethyl isocyanide: an explanation of double soret spectra.
The 2 pH dependent peaks formed in the Soret region by the treatment of reduced hepatic microsomes or purified cytochrome P-448 with ethyl isocyanide do not exhibit identical dependence on ethyl isocyanide concentration. This behavior and other facts regarding double Soret spectra can be explained by a simple expostulation involving lipophilic and corrdinate binding of pi-acceptor ligands.
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D003486:Cyanides / Q000032:analysis; D003577:Cytochrome P-450 Enzyme System / Q000032:analysis; D007700:Kinetics; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology; D013053:Spectrophotometry
D003486:Cyanides; D003577:Cytochrome P-450 Enzyme System