[Effect of experimental allergic encephalomyelitis on the intensity of phospholipid metabolism in the brain and spinal cord].
Metabolism of separate phospholipid fractions was studied in rabbit brain hemispheres, truncus cerebri, cervical and lumbar parts of spinal cord in experimental allergic encephalomyelitis (EAE). Different alterations in metabolic activity of phospholipids in brain and spinal cord were noted in EAE. In brain incorporation of 14C into separate phospholipid fractions was inhibited similarly. In spinal cord the direction of metabolic changes was different: metabolism of phosphatidyl choline and phosphatidyl serine was maximally inhibited in lumbar part and intensity of metabolism of phosphatidyl ethanolamine and phosphatidic acid was increased in cervical part.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002308:Cardiolipins / Q000378:metabolism; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000378:metabolism*; D008297:Male; D010712:Phosphatidic Acids / Q000378:metabolism; D010713:Phosphatidylcholines / Q000378:metabolism; D010714:Phosphatidylethanolamines / Q000378:metabolism; D010718:Phosphatidylserines / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D011817:Rabbits; D013109:Sphingomyelins / Q000378:metabolism; D013116:Spinal Cord / Q000378:metabolism*
D002308:Cardiolipins; D010712:Phosphatidic Acids; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010718:Phosphatidylserines; D010743:Phospholipids; D013109:Sphingomyelins
Vliianie éksperimental'noro allergicheskogo éntsefalomielita na intensivnost' obmena fosfolipidov golovnogo i spinnogo mozga.