A basic experimental approach in perspective of pineal and melatonin involvement in photoperiod-induced alteration of spermatogenesis in toad (Bufo melanostictus).
Blinding decreases spermatogenesis along with Leydig cell degeneration in toad. Pinealectomy decreases spermatogenesis with an increase in Leydig cell activity. Melatonin decreases spermatogenesis as well the Leyding cells. Possibly pineal and melatonin possess an inverse relationship with light and inhibit testis.
D000818:Animals; D001766:Blindness / Q000503:physiopathology; D002025:Bufonidae; D003624:Darkness; D007985:Leydig Cells / Q000187:drug effects / Q000502:physiology; D008027:Light; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D010870:Pineal Gland / Q000502:physiology*; D013091:Spermatogenesis / Q000187:drug effects; D013737:Testis / Q000502:physiology
D008550:Melatonin