Hereditary malformation of the toes and fingers in a family with double translocation heterozygosity.
A hereditary malformation of the metatarsophalangeal joints, called here "tear drop" deformity, and a cut off appearance of the distal phalanges of the toes is described in a family with double translocation t (7; 12), t (2; 6) heterozygosity. A bracydactyly E was also found. These disorders seemed unrelated to the chromosomal aberration.
D000015:Abnormalities, Multiple / Q000235:genetics*; D000293:Adolescent; D005260:Female; D005385:Fingers / Q000002:abnormalities*; D006579:Heterozygote; D006801:Humans; D008297:Male; D014034:Toes / Q000002:abnormalities*; D014178:Translocation, Genetic