The respiratory response in sensitized rats to aerosol challenge.
Hooded Lister rats were sensitized to DNP-ovalbumin. These rats showed a significant alteration in respiratory pattern when challenged with DNP-ovalbumin aerosol. The respiratory response was not produced by challenging sensitized rats with intragastric DNP-ovalbumin. The magnitude of the respiratory response did not correlate with the specific IgE concentration in the serum. A similar pattern of respiratory response was inducible in unsensitized rats by intravenous administration of IgE-rich sera.
D000336:Aerosols; D000818:Animals; D000941:Antigens; D004136:Dinitrobenzenes / Q000008:administration & dosage / Q000276:immunology; D007114:Immunization; D007073:Immunoglobulin E / Q000032:analysis; D010047:Ovalbumin / Q000008:administration & dosage / Q000276:immunology; D010323:Passive Cutaneous Anaphylaxis; D051381:Rats; D011919:Rats, Inbred Strains; D012119:Respiration
D000336:Aerosols; D000941:Antigens; D004136:Dinitrobenzenes; D007073:Immunoglobulin E; D010047:Ovalbumin