Neuromuscular junction blocking agents: an initial screening bioassay.
A simple, rapid and sensitive in vivo bioassay for the initial screening of neuromuscular junction (NMJ) blocking agents has been accomplished. The i.v. retro-orbital plexus (IVROP) mode of injection was utilized, for the first time, in conjunction with the mouse inclined screen bioassay.
D000818:Animals; D001681:Biological Assay; D051379:Mice; D009466:Neuromuscular Blocking Agents / Q000032:analysis*; D014403:Tubocurarine / Q000032:analysis
D009466:Neuromuscular Blocking Agents; D014403:Tubocurarine