Endoscopic appearances and histological changes in ulcer-associated duodenitis.
A simple system of grading the endoscopic appearances of duodenitis is described. There was a good association between the degree of duodenitis recorded using this method and that obtained from a histological grading system in a group of duodenal ulcer patients and a group of dyspeptic patients with no endoscopic evidence of duodenitis. Endoscopic assessment is recommended as a reliable guide to the presence of duodenitis. After 1 month of treatment with cimetidine there was a significant improvement in the endoscopic duodenitis scores of a group of 17 duodenal ulcer patients. In 16 of these patients there was complete ulcer healing. Duodenitis can be a manifestation of chronic duodenal ulcer disease. In the absence of ulceration, the endoscopic diagnosis  of duodenitis is of value in the recognition of patients with this condition.
D000328:Adult; D002927:Cimetidine / Q000627:therapeutic use; D004378:Duodenal Diseases / Q000150:complications / Q000473:pathology*; D004381:Duodenal Ulcer / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D004724:Endoscopy; D004751:Enteritis / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D002927:Cimetidine