The web factor in cholangitis.
Choledochoscopy demonstrates that stone-related suppurative cholangitis has the pathologic characteristics of a multiloculated intraductal abscess. The fibrin web compartmentalizes the duct, traps calculi, and limits spontaneous extrusion. The stones act as foreign bodies and stasis maintains the bacterobilia. This is the anatomic basis and rationale for early direct surgical drainage as the definite effective treatment.
D002761:Cholangitis / Q000150:complications / Q000473:pathology*; D003135:Common Bile Duct / Q000473:pathology*; D005337:Fibrin; D042882:Gallstones / Q000150:complications*; D006801:Humans
D005337:Fibrin