Decreased fructose concentrations in coagulating glands of prepuberal rats treated with testosterone and LH.
Doses of testosterone propionate from 2.5 to 320 microgram and doses of LH from 2 to 360 microgram given over 1--3 days generally decreased fructose/body weight ratios in the coagulating glands of late prepuberal rats. The ratios of testes, seminal vesicles, coagulating glands and ventral prostates to body weight were increased after different treatment regimes with testosterone propionate. These changes in the variables measured could be detected by computer analysis in spite of the rapid growth rates of organs of rats of this age. LH increased the weights of only the seminal vesicles and coagulating glands, and then, only at the highest doses given.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D005088:Exocrine Glands / Q000378:metabolism; D005632:Fructose / Q000378:metabolism*; D005837:Genitalia, Male / Q000187:drug effects / Q000378:metabolism*; D007986:Luteinizing Hormone / Q000494:pharmacology*; D008297:Male; D011467:Prostate / Q000378:metabolism; D051381:Rats; D012669:Seminal Vesicles / Q000378:metabolism; D013737:Testis / Q000378:metabolism; D013739:Testosterone / Q000494:pharmacology*
D005632:Fructose; D013739:Testosterone; D007986:Luteinizing Hormone