Establishment and characterization of two hamster macrophage cell lines.
Two hamster macrophage cell lines (HM-1 and HM-2) were established in vitro from lymphoid tumors produced in hamsters by direct implantation of normal human umbilical cord leukocytes. Despite long-term culture, both cell lines maintained the morphological, functional and surface characteristics of normal macrophages. It is considered that these cell lines were derived from host macrophages infiltrating the heterotransplants.
D000818:Animals; D002460:Cell Line; D006224:Cricetinae; D005312:Fetal Blood / Q000166:cytology; D006801:Humans; D017708:Leukocyte Transfusion; D008223:Lymphoma / Q000473:pathology; D008264:Macrophages / Q000473:pathology*; D009374:Neoplasms, Experimental / Q000473:pathology; D014183:Transplantation, Heterologous