Interaction of cocaine and bunaphtide on the 3H-norepinephrine uptake mechanism on isolated left atrium of guinea-pig.
Bunaphtide induces a blockade in the 3H-norepinephrine uptake and retention in the isolated guinea-pig left atrium. However, this blockade does not seem to be related with the cardiodepressant effect of the drug.
D000818:Animals; D002035:Bunaftine / Q000494:pharmacology*; D003042:Cocaine / Q000494:pharmacology*; D003864:Depression, Chemical; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects*; D066298:In Vitro Techniques; D009206:Myocardium / Q000378:metabolism*; D009281:Naphthalenes / Q000494:pharmacology*; D009638:Norepinephrine / Q000378:metabolism*
D009281:Naphthalenes; D002035:Bunaftine; D003042:Cocaine; D009638:Norepinephrine