title: Impurities in drugs II: meperidine and its formulations.
abstract: Three lots of meperidine hydrochloride, seven lots of meperidine tablets, and 41 lots of meperidine injectables were examined for impurities by TLC. Impurities found were ethyl 1-benzyl-4-phenyl-4-piperidinecarboxylate, methyl-4-piperidinecarboxylate, ethyl-4-phenyl-4-piperidinecarboxylate, and three unidentified compounds. Not all impurities were found in every lot of drug investigated, and none of the impurities exceeded a concentration of 1% of the meperidine present.
mesh_terms: D002855:Chromatography, Thin Layer; D004340:Drug Contamination; D008614:Meperidine / Q000032:analysis / Q000592:standards*
chemical_list: D008614:Meperidine