title: Alcohol and the oculomotor system.
abstract: The influence of alcohol on the oculomotor system was observed by means of the caloric eye tracking pattern (CETP) test, the visual suppression test on caloric nystagmus, and the positional nystagmus, eye tracking and gaze nystagmus tests. In Group A (nine cases whose CETP before the intake of alcohol was normal), the influence of alcohol consumption appeared regularly and consistently in the following order: abnormality of CEPT greater than or equal to positional alcohol nystagmus greater than or equal to abnormality of the eye tracking pattern greater than or equal to alcohol gaze nystagmus. On the contrary, in Group B (eight cases whose CETP before the consumption of alcohol was already abnormal), with one exception, the regularity noted in Group A was not observed. This phenomenon may be attributable to the presence of latent disorders of the oculomotor system. In both groups, the duration of the caloric nystagmus itself was slightly shortened and its amplitude somewhat suppressed after the consumption of alcohol. The results were confirmed by experiments in which the subjects kept their eyes open in darkness. On the other hand, when the eyes were kept open in light surroundings, the duration and amplitude of the caloric nystagmus were exaggerated in appearance because the mechanism of visual suppression was disturbed by alcohol.
mesh_terms: D000328:Adult; D000435:Alcoholic Intoxication / Q000503:physiopathology*; D002150:Caloric Tests; D005133:Eye Movements / Q000187:drug effects*; D005260:Female; D006801:Humans; D009759:Nystagmus, Pathologic / Q000139:chemically induced; D009801:Oculomotor Muscles / Q000187:drug effects*; D009802:Oculomotor Nerve / Q000187:drug effects