title: Bulk flow of cerebrospinal fluid through a lumbo-omental pedicle graft in the dog.
abstract: Perfusion tests were performed in dogs with a pedicle graft of the greater omentum implanted in the lumbar subarachnoid space to measure its capacity to drain CSF. The CSF pressure was set at different levels in the range 0--50 mmHg and the outflow from a complete CSF space and then from the isolated dural sac was recorded in the same dog with an electronic drop recorder. It was shown that the omental graft could transport as much as 30% of the CSF normally carried by the physiological pathways. The spinal outflow in the controls was virtually non-existent. It is concluded that a bulk flow of CSF occurs through the graft. The results suggest that a lumbo-omental pedicle graft could possibly be used as a biological shunt in the treatment of hydrocephalus.
mesh_terms: D000818:Animals; D002555:Cerebrospinal Fluid / Q000502:physiology*; D002557:Cerebrospinal Fluid Shunts / Q000379:methods*; D004285:Dogs; D008161:Lumbosacral Region; D009852:Omentum / Q000637:transplantation*; D013346:Subarachnoid Space / Q000601:surgery*; D014182:Transplantation, Autologous