Irreversible depigmentation of dark mouse hair by T-2 toxin (a metabolite of Fusarium sporotrichioides) and by calcium pantothenate.
T-2 toxin, a trichothecene metabolite of several Fusarium spp. causes depigmentation of dark mouse hair at the site of its application. Calcium pantothenate, though usually considered as antigreying factor, caused depigmentation at the site of its i.p. injections, at high concentration.
D000818:Animals; D005260:Female; D005670:Fusarium; D006197:Hair / Q000187:drug effects*; D051379:Mice; D010205:Pantothenic Acid / Q000494:pharmacology*; D010858:Pigmentation / Q000187:drug effects*; D012717:Sesquiterpenes / Q000494:pharmacology*; D013605:T-2 Toxin / Q000494:pharmacology*
D012717:Sesquiterpenes; D010205:Pantothenic Acid; D013605:T-2 Toxin