Failure of naloxone to reverse peripheral transcutaneous electro-analgesia in patients suffering from acute trauma.
Transcutaneous electrical stimulation of the intercostal nerves innervating the site of fractured ribs in 6 patients produced subjective and clinical evidence of decrease in the pain experienced by the patients. This analgesia was not significantly modified by naloxone, a pure narcotic antagonist. The possible role of endogenous morphine-like substances in peripheral electro-analgesia in man is discussed.
D000208:Acute Disease; D000328:Adult; D004580:Electronarcosis; D005260:Female; D006801:Humans; D007367:Intercostal Nerves / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009270:Naloxone / Q000494:pharmacology*; D012253:Rib Fractures / Q000503:physiopathology*; D013900:Thoracic Nerves / Q000503:physiopathology*
D009270:Naloxone