title: Relationships between IgE antibody production and other immune responses. II. Effect of thymectomy at various times after birth.
abstract: Mice were subjected to thymectomy at various times after birth and immunized with ovalbumin in aluminum hydroxide gel at 4 or 8 weeks of age. The capacities to produce IgE, IgM and IgG antibodies were abolished by thymectomy carried out within 48 h after birth. The capacity to produce IgE antibody was not affected by thymectomy at 7 days or later, whereas the capacities to produce IgM and IgG antibodies were reduced by thymectomy carried out at 4 weeks of age.
mesh_terms: D000818:Animals; D000917:Antibody Formation; D007073:Immunoglobulin E / Q000096:biosynthesis*; D007074:Immunoglobulin G / Q000096:biosynthesis; D007075:Immunoglobulin M / Q000096:biosynthesis; D008211:Lymphocyte Cooperation; D051379:Mice; D010047:Ovalbumin / Q000276:immunology; D013934:Thymectomy; D013950:Thymus Gland / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007073:Immunoglobulin E; D010047:Ovalbumin