Column chromatographic separation of deoxynucleotide monomethyl esters and related products of the reaction of n-methyl-n-nitrosourea with deoxynucleoside monophosphates.
Dowex 1 (HCOO-) column chromatographic procedures are described for the resolution of deoxynucleoside monophosphate monomethyl esters and other related products of the reaction of the carcinogen N-methyl-N-nitrosourea with deoxynucleoside monophosphates. These procedures provide convenient methods for the isolation and estimation of the products of these reactions.
D055598:Chemical Phenomena; D002621:Chemistry; D002853:Chromatography, Liquid / Q000379:methods; D004247:DNA / Q000031:analogs & derivatives*; D008770:Methylnitrosourea; D009607:Nitrosourea Compounds
D009607:Nitrosourea Compounds; D008770:Methylnitrosourea; D004247:DNA