A new type of chondrodystrophic mutant in the mouse.
Stumpy is a new chondrodystrophic mutant in the mouse. The condition is inherited as a fully penetrant Mendelian recessive, and is not allelic with brachymorphic, achondroplasia, or stubby-three similar, previously described mutants. No chromosomal position has yet been assigned to the gene. Phenotypically, stumpy mice are chondrodystrophic dwarfs with all cartilage-formed bones in the skeleton affected. The condition differs from the usual chondrodystrophy described in mice in that proximal elements in the limbs are affected more than distal ones.
D000130:Achondroplasia / Q000235:genetics*; D000818:Animals; D001842:Bone and Bones / Q000002:abnormalities; D003433:Crosses, Genetic; D004195:Disease Models, Animal; D005260:Female; D005808:Genes, Recessive; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA / Q000235:genetics*; D009154:Mutation; D010641:Phenotype