Kinetics of tetrahydrobiopterin synthesis by rabbit brain dihydrofolate reductase.
Product identification and kinetic data are presented for the conversion of 7,8-dihydrobiopterin into tetrahydrobiopterin by purified rabbit brain dihydrofolate reductase.
D000818:Animals; D001708:Biopterins / Q000031:analogs & derivatives / Q000096:biosynthesis*; D001921:Brain / Q000201:enzymology*; D007700:Kinetics; D010651:Phenylalanine Hydroxylase / Q000378:metabolism; D011621:Pteridines / Q000096:biosynthesis*; D011817:Rabbits; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism*
D011621:Pteridines; D001708:Biopterins; D010651:Phenylalanine Hydroxylase; D013762:Tetrahydrofolate Dehydrogenase; C003402:sapropterin