[Hemagglutinins and immunoglobulins in surgical patients and blood donors (author's transl)].
In our investigations 60 patients with severe consuming surgical illness and 61 patients with tumors, especially of the bowel, have shown distinctly higher values of hemagglutinins and immunoglobulins than 60 other patients with slighter disease and 1181 healthy blood donors. Therefore we conclude that those are able to form much more humoral antibodies as supposed up to now, inspite of their severe illness. The stimulation of their immune-system may be caused by resorption of intestinal mucosa, containing compounds identical to the bloodgroup substances A and B, from ulcera and during surgery, or by resorption of similar bacterial antigens e.g. Common-Antigen. The good humoral situation of the tumor patients contrasts to their supposed insufficient cellular immune defense, not tested by us. Therefore the BCG stimulation is only necessary if an insufficient cellular immune situation is proved. X-rays and cytostatica used without severe indication, will destroy the humoral antibodies found by us.
D000017:ABO Blood-Group System; D000917:Antibody Formation; D000942:Antigens, Bacterial; D001782:Blood Donors; D005767:Gastrointestinal Diseases / Q000276:immunology*; D006388:Hemagglutinins; D006801:Humans; D007136:Immunoglobulins; D007519:Isoantigens
D000017:ABO Blood-Group System; D000942:Antigens, Bacterial; D006388:Hemagglutinins; D007136:Immunoglobulins; D007519:Isoantigens
Hämisoagglutinine und Immunglobuline bei chirurgischen Patienten und Blutspendern.