Delayed cerebrovascular consequences of radiation to the neck. A clinicopathologic study of a case.
A man had a stroke 27 years after radiation therapy to the neck for treatment of laryngeal papillomas. There were premonitory symptoms suggesting cerebral ischemia. In contrast to many previously reported cases, in our patient there is a strong relationship between radiation therapy and stroke. Pathoanatomic study of the surgical vascular specimen strongly suggests that radiation is a potentially modifiable cause of delayed stroke.
D000328:Adult; D002340:Carotid Artery Diseases / Q000209:etiology; D002343:Carotid Artery, Internal / Q000528:radiation effects; D002561:Cerebrovascular Disorders / Q000209:etiology*; D005350:Fibroma / Q000532:radiotherapy*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy*; D008297:Male; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D013997:Time Factors