Induction of epidermal cell proliferation by a tumour promoter in vitamin B6-deficient mice.
Topical application of the tumour promoter 12-0-tetradecanoyl-phorbol-13-acetate to skin caused a marked enhancement of mitotic activity both in mice maintained on a complete diet or on a vitamin B6-deficient diet.
D000818:Animals; D005260:Female; D051379:Mice; D008938:Mitosis / Q000187:drug effects; D010704:Phorbols / Q000494:pharmacology*; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology*; D026681:Vitamin B 6 Deficiency; D014804:Vitamin B Deficiency / Q000473:pathology*
D010704:Phorbols; D013755:Tetradecanoylphorbol Acetate