Use of the one-hour blood xylose test as an indicator of small bowel mucosal disease.
The one-hour blood xylose concentration was evaluated to determine its usefulness as a screening test for small bowel mucosal disease in infants and children. Six of 13 patients with one-hour blood xylose levels of less than 20 mg/dl had normal small bowel biopsies by light microscopy. Five of 20 children with normal one-hour xylose levels had abnormal small bowel villous architecture. Because of the significant false positive (46%) and false negative results (25%), the one-hour blood xylose concentration should not be used as the sole indicator for small bowel biopsy in infants and children with chronic diarrhea.
D001706:Biopsy; D002338:Carotenoids / Q000097:blood; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007410:Intestinal Diseases / Q000097:blood / Q000175:diagnosis / Q000473:pathology; D007413:Intestinal Mucosa / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology; D013997:Time Factors; D014994:Xylose / Q000097:blood
D002338:Carotenoids; D014994:Xylose