Malignant lymphoma of plasmablastic identity. A neoplasm with both "immunoblastic" and plasma cellular features.
A solitary extramedullary lymphoid neoplasm had characteristics of plasma cell precursors or plasmablasts. Conventional microscopic study classified this tumor as a diffuse large cell lymphoma of "immunoblastic sarcoma" type. Immunologic cell surface markers could not be detected, but cytoplasmic immunoglobulin G (IgG)-kappa was demonstrated by immunoperoxidase technic, and IgG was present in the supernatant of the tumor tissue culture. The distinction between lymphoid and plasma cellular neoplasms is made.
D000368:Aged; D005260:Female; D006801:Humans; D007120:Immunochemistry; D008223:Lymphoma / Q000276:immunology / Q000473:pathology*