Quinidine-induced hemolytic anemia: immunohematologic characterization.
A 40-year-old white male with quinidine induced hemolytic anemia but no thrombocytopenia is described. Hemolysis was extravascular in nature and via the immune-complex mechanism. The quinidine antibody was an IgG immunoglobulin that did not activate complement.
D000328:Adult; D000743:Anemia, Hemolytic / Q000097:blood / Q000139:chemically induced* / Q000276:immunology; D000906:Antibodies; D000918:Antibody Specificity; D006801:Humans; D007074:Immunoglobulin G; D007667:Kidd Blood-Group System; D008297:Male; D011802:Quinidine / Q000009:adverse effects* / Q000276:immunology
D000906:Antibodies; D007074:Immunoglobulin G; D007667:Kidd Blood-Group System; D011802:Quinidine