Treatment of menopausal oestrogen deficiency symptoms in hysterectomised women by means of 17beta-oestradiol pellet implants.
Ninety-four women having undergone hysterectomy, with or without simultaneous ovariectomy, were treated for menopausal symptoms by means of subcutaneous implantation of sterile pellets containing 20 mg 17beta-oestradiol, 589 implantations in all. The subjective effect was good and lasted generally for about 6 months. The Karyopyknotic index, serum FSH and plasma oestradiol were checked in a few of the patients. The method was judged to be valuable in appropriate cases.
D000328:Adult; D000368:Aged; D004343:Drug Implants; D004958:Estradiol / Q000008:administration & dosage* / Q000097:blood / Q000627:therapeutic use; D004967:Estrogens / Q000172:deficiency*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007044:Hysterectomy; D008593:Menopause; D008875:Middle Aged
D004343:Drug Implants; D004967:Estrogens; D004958:Estradiol; D005640:Follicle Stimulating Hormone