[Extramembranous glomerulitis associated with visceral tumours. Clinical and histological study based upon 10 cases and a review of the literature (author's transl)].
The frequency of the association between extramembranous glomerulopathy and a visceral tumour suggests the responsibility of various antigen-antibody systems related to malignancy, at the origin of the nephropathy. In a number of special cases, the role of these systems has been more precisely demonstrated. The cases reported here emphasise the need to seek a visceral tumour when the onset of extramembranous glomerulitis occurs after the age of 40 years, in particular since the onset of proteinuria may precede the first clinical signs of the tumour by several months. The presence of polynuclear cells in the glomerular capillary loops, associated with extramembranous deposits, is an additional element of orientation in the direction of neoplastic aetiology.
D000230:Adenocarcinoma / Q000150:complications; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000150:complications; D001984:Bronchial Neoplasms / Q000150:complications; D002294:Carcinoma, Squamous Cell / Q000150:complications; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D007822:Laryngeal Neoplasms / Q000150:complications; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D010190:Pancreatic Neoplasms / Q000150:complications; D011471:Prostatic Neoplasms / Q000150:complications; D013274:Stomach Neoplasms / Q000150:complications
Glomérulites extra-membraneuses associées aux tumeurs viscérales. Etude clinique et histologique à propos de 10 cas et revue de la littérature.