[Effect of sodium transport inhibitors on maximal glucose reabsorption and cardiotrast excretion by the kidneys].
Effects of intrarenal infusion of potassium cyanide and strophanthinum were studied in acute experiments on dogs. The decrease fractional of reabsorption of sodium to 80--82 per cent did not affect renal reabsorption of glucose and tubular excretion of cardiotrast. Combined infusion of strophanthinum and cyanide decreased the fractional sodium reabsorption to 65.6 per cent. During this period maximal reabsorption of glucose reduced but not so the tubular excretion of cardiotrast.
D000042:Absorption; D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D004231:Diuresis / Q000187:drug effects; D004285:Dogs; D005947:Glucose / Q000378:metabolism*; D007468:Iodopyracet / Q000378:metabolism*; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism; D007684:Kidney Tubules / Q000187:drug effects; D009318:Natriuresis / Q000187:drug effects; D011189:Potassium Chloride / Q000494:pharmacology; D012964:Sodium / Q000037:antagonists & inhibitors*; D013328:Strophanthins / Q000494:pharmacology; D013997:Time Factors
D013328:Strophanthins; D011189:Potassium Chloride; D012964:Sodium; D005947:Glucose; D007468:Iodopyracet
Vliianie ingibitorov transporta natriia na maksimal'nuiu reabsorbtsiiu gliukozy i sekretsiiu kardiotrasta v pochkakh.