Do beta adrenergic agents directly stimulate gastrin secretion?
Isoproterenol if given during methacholine stimulation in dogs neither depresses gastric secretion nor elevates serum gastrin. Therefore, we conclude that beta adrenergics (isoproterenol) are unlikely to be direct liberators of gastrin, but raise serum gastrin indirectly only if they inhibit gastric secretion.
D000818:Animals; D004285:Dogs; D005755:Gastrins / Q000378:metabolism*; D007545:Isoproterenol / Q000494:pharmacology*; D008688:Methacholine Compounds / Q000494:pharmacology; D010418:Pentagastrin / Q000378:metabolism
D005755:Gastrins; D008688:Methacholine Compounds; D010418:Pentagastrin; D007545:Isoproterenol