title: A balanced translocation t(11;16)(q13;p11), a cytogenetic study and an attempt at gene localization.
abstract: Members of three generations of a single family were examined and found to have a balanced translocation t(11;16)(q13;p11). Cytogenetic investigation and investigation of a number of gene markers is consistent with the current view that the Hp-alpha locus is situated in the proximity of band 16q22.
mesh_terms: D000328:Adult; D000649:Amniocentesis; D002902:Chromosomes, Human, 16-18; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007621:Karyotyping; D010375:Pedigree; D010641:Phenotype; D011296:Prenatal Diagnosis; D014178:Translocation, Genetic