[Effect of polymer complexons based on vinylpyrrolidone copolymers with vinyliminodiacetic acid and methacrtloylacetone on the antibiotic sensitivity of antibiotic-resistant bacterial strains].
Polymer complexons, such as copolymers of vinylpyrrolidone with vinyliminodiacetic acid and metacryloilacetone changed the permeability of the bacterial cell wall due to chelating of the metalic ions contained in the cell wall. An increase in the bacterial sensitivity to chloretracycline, methicillin, ampicillin and methicillin was observed in the presence of the above complexons.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002463:Cell Membrane Permeability / Q000187:drug effects; D002614:Chelating Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004357:Drug Synergism; D008689:Methacrylates; D008826:Microbial Sensitivity Tests; D011205:Povidone / Q000031:analogs & derivatives* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D002614:Chelating Agents; D008689:Methacrylates; D011205:Povidone
Vliianie polimernykh kompleksonov na osnove sopolimerov vinilpirrolidona s vinilimodiuksusnoĭ kislotoĭ i metakriloilatsetonom na chuvstvitel'nost'k antibiotikam antibiotikoustoĭchivykh shtammov bakteriĭ.