[Reaction of rats to the effect of hyperbaric oxygenation after preliminary adaptation to hypoxia].
Preliminary adaptation of rats to hypoxia in the regimen exceeding the resistance to many stress agents not only produced no protective effect in response to the action of increased oxygen pressure (IOP) up to 6 kg/cm2, but, on the contrary, decreased the organism resistance. Thus, the time of occurrence of convulsions in the adapted rats was shortened, particularly when IOP acted 24 or 48 hours after the termination of training to hypoxia; this effect was somewhat weaker in experiments conducted in 3 to 4 days. Reactions became completely normal one month after the termination of training to hypoxia. Possible causes of the phenomena detected are discussed.
D000222:Adaptation, Physiological; D000818:Animals; D006931:Hyperbaric Oxygenation; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D010101:Oxygen Consumption; D051381:Rats; D012640:Seizures / Q000209:etiology
Reaktsiia krys na deĭstvie kisloroda pod povyshennym davleniem posle predvaritel'noĭ adaptatsii k gipoksii.