[Ion excretion by the rat kidney in depressed reabsorption in proximal tubule and ascending protion of the loop of Henle].
Simultaneous suppression of reabsorption in the proximal tubule with the aid of polyethylenglucole 400 (PEG) and in ascending part of Henle's loop with furosemide increased diuresis by 121 times and natri-uresis by 242 times on the average. The increase was based on changes in the tubule reabsorption and secretion. The changes of sodium and calcium excretion as well as excretion of potassium and magnesium were parallel. Excretion of sodium and calcium was lesser than the diuresis while that of magnesium and potassium exceeded it. Furosemide reduced the reabsorption of osmotically free water.
D000042:Absorption; D000818:Animals; D004231:Diuresis / Q000187:drug effects*; D005665:Furosemide / Q000494:pharmacology; D007684:Kidney Tubules / Q000187:drug effects*; D007687:Kidney Tubules, Proximal / Q000187:drug effects*; D008138:Loop of Henle / Q000187:drug effects*; D009318:Natriuresis / Q000187:drug effects*; D011092:Polyethylene Glycols / Q000494:pharmacology; D051381:Rats; D013997:Time Factors; D014882:Water-Electrolyte Balance / Q000187:drug effects
D011092:Polyethylene Glycols; D005665:Furosemide
Vydelenie ionov pochkoĭ krysy pri ugnetenii reabsorbtsii v proksimal'nom kanal'tse i voskhodiashchem otdele petli Genle.