title: [Regularity in the extreme character of the ontogenetic development of ovarian activity in the reproductive function self-regulation system].
abstract: Opposite conclusions were drawn depending on the sex hormones which different authors used to assess the functional condition of the ovaries at various age periods. A new index--reception coefficient (RC)--is suggested proceeding from the systemic approach to find the way out from this inconsistency. This coefficient represents the ratio of the peripheral hormone value and the gonadotropin level inducing it. Regularities of the extreme character in the ontogenetic development of the ovarian activity were established by means of RC: the maximum ovarian function under normal conditions fell on the age group of 20--29 years, and the minimum--on the age groups of under 7 and over 50 years. A sharp decline of the ovarian function began in the age group of 40--49 years.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D004967:Estrogens / Q000652:urine; D005260:Female; D006062:Gonadotropins / Q000652:urine; D006706:Homeostasis; D006801:Humans; D008593:Menopause; D008598:Menstruation; D008875:Middle Aged; D010053:Ovary / Q000254:growth & development* / Q000502:physiology; D012016:Reference Values; D012098:Reproduction; D013597:Systems Analysis
chemical_list: D004967:Estrogens; D006062:Gonadotropins
vernacular_title: Zakonomernost' ékstremal'nogo kharaktera ontogeneticheskogo razvitiia deiatel'nosti iaichnikov v sisteme samoreguliatsii reproduktivnoĭ funktsii.