Systemic anaphylaxis secondary to the use of 5 per cent plasma protein fractions.
A severe anaphylactic reaction developed in a twenty-six year old female after the administration of only 40 ml of 5 per cent plasma protein fractions (Plasmanate). The reaction was characterized by generalized tingling, chest pain, sudden severe hypotension, and urticaria. The patient responded to intravenous fluid, epinephrine, diphenylhydramine, and steroid administration.
D000328:Adult; D000707:Anaphylaxis / Q000209:etiology*; D001798:Blood Proteins / Q000008:administration & dosage*; D001920:Bradykinin / Q000494:pharmacology; D005260:Female; D006801:Humans; D007022:Hypotension / Q000209:etiology; D010952:Plasma Substitutes / Q000009:adverse effects*; D000075462:Serum Albumin, Human; D012712:Serum Globulins
D001798:Blood Proteins; D010952:Plasma Substitutes; D012712:Serum Globulins; C008930:plasma protein fraction; D001920:Bradykinin; D000075462:Serum Albumin, Human