[Ultrastructure of epithelial cells and cell contacts in the urinary bladder of frogs treated with aminazine].
Chlorpromazine induced swelling and vacuolization of cells of the frog urinary bladder mucosa and eliminated their capacity to react to antidiuretic hormone by increased water permeability. The structure of the tight junction and desmosoma is unchanged, this possibly determining the water-tightness of the epithelium treated with chlorpromazine.
D000818:Animals; D001001:Anura; D002463:Cell Membrane Permeability / Q000187:drug effects; D002746:Chlorpromazine / Q000494:pharmacology*; D004848:Epithelium / Q000187:drug effects; D007365:Intercellular Junctions / Q000187:drug effects*; D001743:Urinary Bladder / Q000187:drug effects*; D014667:Vasopressins / Q000037:antagonists & inhibitors*; D014867:Water / Q000378:metabolism
D014867:Water; D014667:Vasopressins; D002746:Chlorpromazine
Ul'trastruktura épitelial'nykh kletok i kletochnykh kontaktov v mochevom puzyre liagushki pri vozdeĭstvii aminazinom.