title: Asthma, allergy and bronchial hyper-reactivity to histamine in patients with bronchiectasis.
abstract: An allergy examination was made on forty-eight consecutive bronchiectasis patients, with a mean age of 37 years. Eleven had confirmed asthma and another nine, making twenty in all (42%), had distinct allergic diathesis. Allergy to a specific allergen was established in five cases. 50% of the patients in the total series had bronchial histamine hyper-reactivity, eleven without asthma or distinct allergic diathesis. The results corroborate views previously reported of the role of asthmatic symptoms and allergic diathesis as aetiological factors of bronchiectasis.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001249:Asthma / Q000276:immunology*; D001980:Bronchi / Q000187:drug effects / Q000276:immunology*; D001987:Bronchiectasis / Q000276:immunology*; D005260:Female; D006632:Histamine / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012130:Respiratory Hypersensitivity / Q000276:immunology*; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology
chemical_list: D006632:Histamine