Pituitary fibrosarcoma secondary to radiation therapy.
A patient who received postoperative radiation therapy for the treatment of a chromophobe adenoma developed a fibrosarcoma of the pituitary gland region 10 years later. A single course of irradiation was given with a total dose to the pituitary of 4092 rad in 21 fractions and 29 days using Cobalt 60 radiation at a source to skin distance of 80 cm.
D000238:Adenoma, Chromophobe / Q000473:pathology / Q000532:radiotherapy*; D005354:Fibrosarcoma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000209:etiology* / Q000473:pathology; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D010911:Pituitary Neoplasms / Q000209:etiology* / Q000473:pathology / Q000532:radiotherapy; D011879:Radiotherapy Dosage