Modified NF method for quantitative determination of pentaerythritol tetranitrate.
A modified NF method for the quantitative determination of pentaerythritol tetranitrate is reported. A solution of powder is made directly from the dosage form in glacial acetic acid and is then reacted with phenoldisulfonic acid TS. The proposed method saves approximately 75% of the time required with the NF method. The results on six differnet commercial dosage forms with four different colors and three other active ingredients are reported.
D008722:Methods; D010417:Pentaerythritol Tetranitrate / Q000032:analysis*; D010602:Pharmacopoeias as Topic; D014481:United States
D010417:Pentaerythritol Tetranitrate