Inhibition of mitogen-induced lymphocyte proliferative responses by quinine.
In vitro mitogen-induced proliferative responses of human lymphocytes were inhibited by concentrations of quinine normally attainable during therapy of malaria infections. The clinical implications of these findings are discussed.
D000328:Adult; D006801:Humans; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000187:drug effects*; D008934:Mitogens / Q000494:pharmacology; D011803:Quinine / Q000276:immunology / Q000494:pharmacology*
D008934:Mitogens; D011803:Quinine