[Effect of thyrocalcitonin on mineral metabolism in experimental osteoporosis].
By the method of radioactive indication of ashed specimens of the femur, tibia, jaw bones and molars on a model of experimental osteoporosis in rats it is shown that the degree of mineralization of calcified tissues increases under the effect of thyrocalcitonin (TCT). The hypermineralization of jaw bones and, especially, of molars was attended by a lower 45Ca inclusion in these tissues. The structure of the adrenal cortex, kidneys, pancreas and thyroid returned back to normal under the effect of TCT and with carbohydrate rich nutrition, this occurring against the background of a high 45Ca concentration in these organs.
D000818:Animals; D002114:Calcinosis / Q000378:metabolism; D002116:Calcitonin / Q000627:therapeutic use*; D002118:Calcium / Q000378:metabolism*; D003743:Dental Enamel / Q000378:metabolism / Q000648:ultrastructure; D004353:Drug Evaluation, Preclinical; D005269:Femur / Q000378:metabolism; D005360:Fibula / Q000378:metabolism; D007568:Jaw / Q000378:metabolism; D010024:Osteoporosis / Q000188:drug therapy / Q000378:metabolism*; D051381:Rats; D013977:Tibia / Q000378:metabolism; D014074:Tooth Calcification / Q000187:drug effects
D002116:Calcitonin; D002118:Calcium
Vliianie tirokal'tsitonina na mineral'nyĭ obmen pri éksperimental'nom osteoporoze.