Changes of profiles of neutrophil granulocytes induced with the administration of L-DOPA and prednisolone.
Morphological changes of granulocytes following combined treatment with L-DOPA and prednisolone were elucidated at the electron microscopic level. Neutrophil granulocytes exhibited marked changes in their surface as evidenced by scanning electron microscope. It is suggested that neutrophil granulocytes are sensitive to some biogenic amines.
D000818:Animals; D001491:Basophils / Q000648:ultrastructure; D004804:Eosinophils / Q000648:ultrastructure; D006098:Granulocytes / Q000187:drug effects* / Q000648:ultrastructure; D007962:Leukocytes / Q000187:drug effects*; D007980:Levodopa / Q000494:pharmacology*; D008297:Male; D009504:Neutrophils / Q000187:drug effects* / Q000648:ultrastructure; D011239:Prednisolone / Q000494:pharmacology*; D051381:Rats; D013499:Surface Properties
D007980:Levodopa; D011239:Prednisolone