Influence of phenylbutazone on bile flow in the rat.
Phenylbutazone, a well-known enzyme inducer, at a dose of 80 mg . kg-1 once daily for 8 days increases liver weight and bile flow expressed per g of liver (p less than 0.01). The bile salt secretory rate is not increased.
D000818:Animals; D001646:Bile / Q000378:metabolism*; D001647:Bile Acids and Salts / Q000378:metabolism; D008099:Liver / Q000187:drug effects; D009929:Organ Size / Q000187:drug effects; D010653:Phenylbutazone / Q000494:pharmacology*; D051381:Rats; D012636:Secretory Rate / Q000187:drug effects
D001647:Bile Acids and Salts; D010653:Phenylbutazone