[Hemodynamic changes upon nociceptive stimulation and stimulation of the amygdaloid complex following catecholamine administration].
In cats, changes in arterial pressure (AP), intracardiac pressure (ICP), and blood flow volume rate following a nociceptive stimulus, stimulation of the amygdala and the combination of these before and after adrenaline (A) and norepinephrine (NE) administration into the lateral nucleus of amygdala, were studied. Nociceptive stimuli and electric stimulation of amygdala increased AP and ICP. The combination of these increased the pressor reaction. The blood flow volume rate was not altered by the nociceptive stimulus while decreasing at amygdalar stimulation. After A and NE administration the stimulation of amygdala plus the nociceptive stimulus suppressed the pressor reaction; a nociceptive stimulus was followed by the same changes as in intact cats; a nociceptive stimulus plus the stimulation of the amygdala increased the pressor reaction. The blood flow volume rate response to the stimuli was the same as in the control group. But the stimulation of amygdala after NE and a nociceptive stimulus plus amygdala stimulation (20 min after A) increased the blood flow volume rate, while the stimulation of amygdala alone with A administration reduced the blood flow.
D000679:Amygdala / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D001783:Blood Flow Velocity; D001794:Blood Pressure / Q000187:drug effects; D002395:Catecholamines / Q000494:pharmacology*; D002415:Cats; D004837:Epinephrine / Q000494:pharmacology; D006439:Hemodynamics; D009638:Norepinephrine / Q000494:pharmacology; D010146:Pain
D002395:Catecholamines; D009638:Norepinephrine; D004837:Epinephrine
Izmenenie gemodinamiki pri notsitseptivnom razdrazhenii i stimuliatsii mindalevidnogo kompleksa posle vvedeniia katekholaminov.