Controlled drug release from polymers.
Unlike conventional routes of drug administration, controlled-release systems that use implanted, inserted, or surface-applied noninflammatory polymeric vehicles can deliver a steady quantity of drug to a target area over long periods of time. This is now true for drugs of both high and low molecular weight. Some of the devices are described, and existing as well as potential clinical applications are discussed.
D000818:Animals; D003692:Delayed-Action Preparations; D004285:Dogs; D006801:Humans; D007700:Kinetics; D008970:Molecular Weight; D011108:Polymers; D011145:Polyvinyls; D011817:Rabbits; D051381:Rats; D012826:Silicone Elastomers
D003692:Delayed-Action Preparations; D011108:Polymers; D011145:Polyvinyls; D012826:Silicone Elastomers