title: [Auto-immune haemolytic anaemia and mediastinal dysembryoma in a 6-year-old child (author's transl)].
abstract: In a six-year-old girl, suffering from an auto-immune haemolytic anaemia, routine radiological examination revealed the presence of a mediastinal tumour which was removed surgically and proved to be a multiple tissue polycystic dysembryoma. Haemolysis and signs of anti-erythrocyte auto-immunisation disappeared after the operation and total and stable cure obtained with a follow-up of 15 months. The target antigen of the anti-erythrocyte autoantibody could not be found within the tumour. However, the latter contained lymphoid tissue and a considerable quantity of antibody. Although indirect, these findings offer arguments in favour of the secretion of autoantibodies by the dysembryoma.
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000000981:diagnostic imaging* / Q000276:immunology; D001323:Autoantibodies / Q000032:analysis; D002648:Child; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging* / Q000276:immunology; D011859:Radiography; D013724:Teratoma / Q000000981:diagnostic imaging* / Q000276:immunology
chemical_list: D001323:Autoantibodies
vernacular_title: Anémie hémolytique auto-immune et dysembryome médiastinal chez une enfant de 6 ans.