title: [Combined action of vibration and ionizing radiation on the body].
abstract: The effect of vibration on the development and outcome of radiation injury was studied and the efficacy of pharmacochemical and local protection was measured. The biological effect of the combined exposure was estimated by radiobiological and hematological methods. The animals were exposed to vibration with a frequency of 70, 700, 1500 Hz (during single and repeated exposures) and irradiation with X-rays, gamma-rays and protons at different doses. Vibration may exert a significant effect on the development and outcome of radiation injury of animals. The effect was that this factor was capable either of increasing or decreasing responses of the animal body to ionizing radiation. The direction and level of changes depended on the pattern and force of stimulation, time and sequence of action of factors, etc. The lymph tissue showed high sensitivity to vibration. The findings indicate that vibration may both enhance and diminish the efficacy of antiradiation pharmacochemical drugs.
mesh_terms: D000818:Animals; D001772:Blood Cell Count; D003538:Cystamine / Q000627:therapeutic use; D003539:Cystaphos / Q000627:therapeutic use; D004285:Dogs; D051379:Mice; D011830:Radiation Effects; D011833:Radiation Injuries, Experimental / Q000188:drug therapy / Q000401:mortality; D011837:Radiation-Protective Agents; D051381:Rats; D013997:Time Factors; D014732:Vibration / Q000009:adverse effects*
chemical_list: D011837:Radiation-Protective Agents; D003538:Cystamine; D003539:Cystaphos
vernacular_title: Kombinirovannoe deĭstvie vibratsii i ioniziruiushchego izlucheniia na organizm.