Chromosome-damaging effect of betel leaf.
The chewing of betel leaf with other ingredients is a widespread addiction in India. The chromosome damaging effect was studied in human leukocyte cultures. There was an increase in the frequency of chromatid aberrations when the leaf extract was added to cultures.
D000293:Adolescent; D000328:Adult; D001114:Areca; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects; D006801:Humans; D007962:Leukocytes / Q000648:ultrastructure; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal
D010936:Plant Extracts