Platelet taurine uptake in spinocerebellar degeneration.
The uptake of 14C-taurine was studied in the platelets of 20 ataxic patients and 20 age-matched normal control subjects. No significant differences were found in uptake or kinetics of taurine between the two groups of subjects. If a transport defect in taurine exists in Friedreich's ataxia, it is not present in all tissues. Preliminary indication was obtained in favor of heterogenity of the uptake pattern between ataxic individuals.
D000293:Adolescent; D000328:Adult; D001259:Ataxia / Q000097:blood; D001792:Blood Platelets / Q000378:metabolism*; D005260:Female; D005621:Friedreich Ataxia / Q000097:blood*; D006801:Humans; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D013654:Taurine / Q000097:blood*
D013654:Taurine