title: 51Cr release cytotoxicity assay evaluated with fluoride and cadmium.
abstract: The sensitivity of the 51Cr release assay was evaluated with two known cytotoxic agents; fluoride and cadmium. The sensitivity was far less than that of other assays, e.g. growth inhibition of cultured cells, and additional a two-peaked dose-response curve was found with cadmium.
mesh_terms: D002104:Cadmium / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects*; D002860:Chromium Radioisotopes; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism; D005459:Fluorides / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged
chemical_list: D002860:Chromium Radioisotopes; D002104:Cadmium; D005459:Fluorides