title: Hypotensive anesthesia for spinal fusion with sodium nitroprusside.
abstract: Deliberate induced hypotension for spinal fusion has been used in the past, but a search for better techniques continues. The authors used sodium nitroprusside by intravenous infusion to reduce the mean arterial pressure from 72 to 42 torr in 10 cases. This degree of hypotension provided an optimal surgical field and maintained adequate tissue perfusion as demonstrated by arterial oxygen tensions greater than 600 torr, no development of base deficit, and continuous urinary excretion. There were no complications related to hypotension. None of the patients received blood transfusions, whereas in the past, 2000 ml blood was usually required for this procedure.
mesh_terms: D000328:Adult; D000769:Anesthesia, Inhalation; D005260:Female; D005292:Ferricyanides / Q000008:administration & dosage; D006801:Humans; D007023:Hypotension, Controlled; D007275:Injections, Intravenous; D008297:Male; D009599:Nitroprusside / Q000008:administration & dosage; D013123:Spinal Fusion
chemical_list: D005292:Ferricyanides; D009599:Nitroprusside