A general procedure for estimation of corticosteroid response in individual rats.
A procedure is presented whereby microliter volumes of plasma, obtained rapidly and repeatedly from the tail vein of unanesthetized rats, can be analyzed for corticosterone. Preliminary results suggest that (1) basal levels are considerably lower and (2) the latency to corticosteroid stress response is shorter than previously reported.
D000818:Animals; D003345:Corticosterone / Q000097:blood*; D008297:Male; D008832:Microchemistry; D011863:Radioimmunoassay / Q000379:methods; D051381:Rats; D013312:Stress, Physiological / Q000097:blood
D003345:Corticosterone