title: Evolution of a human Y chromosome-specific repeated sequence.
abstract: The structure and evolution of a repetitive sequence on the human Y chromosome has been studied by restriction enzyme analysis of both total DNA and the isolated sequence. The sequence is shown to cross-hybridize to sequences in female DNA forming unstable duplexes. Mouse/human cell hybrids have been used to investigate the pattern of sequence homology on the X chromosome and some autosomes. We conclude that this sequence is related to human satellite III, but shows considerable differences in structure.
mesh_terms: D001483:Base Sequence; D005075:Biological Evolution; D004247:DNA; D004262:DNA Restriction Enzymes; D004276:DNA, Satellite; D005260:Female; D006801:Humans; D006822:Hybrid Cells; D008297:Male; D009693:Nucleic Acid Hybridization; D012730:Sex Chromosomes / Q000032:analysis*; D014998:Y Chromosome / Q000032:analysis*
chemical_list: D004276:DNA, Satellite; D004247:DNA; D004262:DNA Restriction Enzymes