title: [Effect of prostaglandin F2alpha on several morphofunctional characteristics of mouse embryos during the pre-implantation period of development].
abstract: Prostaglandin F2alpha in vivo and in vitro effects were studied in mouse embryos at different developmental stages. Inhibiting effect of this factor on cell reproduction (cleavage) was demonstrated, and in vivo experiments the process of the embryo release from the zona pellucida was also investigated. The studies were carried out in a large statistically significant material with an adequate mathematical processing of the data obtained. The critical point of the greatest sensitivity in the embryo to prostaglandin F2alpha effect was determined--the morula stage (16 cells).
mesh_terms: D000818:Animals; D047108:Embryonic Development / Q000187:drug effects*; D005260:Female; D051379:Mice; D010063:Ovum / Q000187:drug effects*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D011460:Prostaglandins F / Q000494:pharmacology*; D015044:Zona Pellucida / Q000187:drug effects*
chemical_list: D011460:Prostaglandins F
vernacular_title: Vliianie prostaglandina F2alpha na nekotorye morfofunktsional'nye kharakteristiki émbriona myshi v doimplantatsionnyĭ period razvitiia.