[Membrane-ionic mechanism of the depressing action of adrenaline on giant neurons].
The depressing action of epinephrine on the giant neurons is due to a progressively increasing passive potassium conductivity of the membrane, hyperpolarization and derangement of its generating properties. The triggering factor in the mechanism of the developing epinephrine hyperpolarization is an epinephrine induced increment of passive potassium conduction of the neuronal membrane.
D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D003864:Depression, Chemical; D004837:Epinephrine / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects; D008974:Mollusca; D009431:Neural Conduction / Q000187:drug effects; D009441:Neurilemma / Q000187:drug effects*; D009474:Neurons / Q000187:drug effects*
D004837:Epinephrine
Membranno-ionnyĭ mekhanizm ugnetaiushchego deĭstviia adrenalina na gigantskie neĭrony.