title: Two methods for producing peripheral anosmia in dogs.
abstract: Two methods for producing peripheral anosmia in the dog were described. One method involved infusion of 3.5% zinc sulfate into the nasal cavity. An anosmia lasting at least 6 weeks, and, in most cases, for several months, was produced. A second technique, producing short periods of reversible anosmia, was the insertion of a tracheostomy tube with inflatable cuff. Inflation of the cuff prevented the dogs from inhaling air over the olfactory mucosa. Deflation of the cuff restored functional olfaction. The advantages and disadvantages of each technique were discussed.
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000139:chemically induced / Q000209:etiology*; D004285:Dogs / Q000502:physiology; D005260:Female; D008297:Male; D008722:Methods; D000857:Olfaction Disorders / Q000139:chemically induced / Q000209:etiology / Q000662:veterinary*; D012903:Smell / Q000187:drug effects / Q000502:physiology; D013431:Sulfates / Q000494:pharmacology; D014140:Tracheotomy / Q000379:methods / Q000662:veterinary*; D015032:Zinc / Q000494:pharmacology
chemical_list: D013431:Sulfates; D015032:Zinc