Brain death, apneic diffusion oxygenation, and organ transplantation.
This paper presents a simple method of maintaining good donor organ oxygenation during a prolonged test of apnea used to determine brain death prior to cadaver transplantation. Apneic diffusion oxygenation can maintain arterial pO2 above 200 torr for periods exceeding 15 minutes, thereby allowing a more definitive determination of brain death without concomitant tissue hypoxia and possible damage to donor organs.
D000328:Adult; D000368:Aged; D001049:Apnea; D001926:Brain Death; D002102:Cadaver; D002245:Carbon Dioxide / Q000097:blood; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009926:Organ Preservation / Q000379:methods*; D010100:Oxygen / Q000097:blood; D014019:Tissue Donors; D014021:Tissue Preservation / Q000379:methods*; D014180:Transplantation
D002245:Carbon Dioxide; D010100:Oxygen