Reconsideration of a test for dopaminergic stimulation: inability of apomorphine to induce mouse jumping.
Apomorphine was administered parenterally to mice in an unsuccessful attempt to induce amphetamine and L-3,4-dihydroxyphenylalanine-like elicited jumping. The efficacy of jumping behavior as an indicator of dopaminergic overstimulation is criticized in light of the results.
D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects*
D001058:Apomorphine; D004298:Dopamine