Isolation of the major toxic protein from the skin venom of the crested newt, Triturus cristatus.
A new protein, of molecular weight 160,000, was isolated from the skin venom of the crested newt and partially characterized by bioassays and biochemical methods. This protein shows the same functional properties as the crude venom, which produces convulsions in mice and is cytotoxic.
D000664:Amphibian Venoms / Q000302:isolation & purification*; D000818:Animals; D002850:Chromatography, Gel; D003292:Convulsants / Q000302:isolation & purification; D004591:Electrophoresis, Polyacrylamide Gel; D051379:Mice; D008970:Molecular Weight; D011506:Proteins / Q000302:isolation & purification* / Q000633:toxicity; D012455:Salamandridae; D014562:Caudata
D000664:Amphibian Venoms; D003292:Convulsants; D011506:Proteins