Neurologic activity of infants following anesthesia for cesarean section.
Elective cesarean section was performed in a consecutive series of 30 patients with full-term pregnancies who were not in labor. Epidural (lidocaine, 1.5 per cent, with epinephrine, 1:200,000) and general anesthesia (thiopental, nitrous oxide-oxygen, succinylcholine infusion) was used alternately. Neonatal acid-base values and Apgar scores showed no significant difference between the two anesthetic groups, and most infants were vigorous at birth. The neurologic recoveries of the infants showed no significant difference between the two groups. In the group receiving epidural anesthesia, there was a significant correlation between maternal hypotension and weak rooting and sucking reflexes of the infants during the first two days. All infants of high-risk obstetric patients in the series, independent of anesthetic technique used, had abnormal neurologic activity, as evidenced by either depression of muscle tone and the reflexes or all the tested variables. Neurologic assessment as followed in this series is a sensitive indicator of the effects of fetal stress factors acting during cesarean section.
D000328:Adult; D000767:Anesthesia, Epidural; D000768:Anesthesia, General; D000773:Anesthesia, Obstetrical; D001034:Apgar Score; D001724:Birth Weight; D002585:Cesarean Section; D004837:Epinephrine; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008012:Lidocaine; D008297:Male; D009460:Neurologic Examination; D009609:Nitrous Oxide; D011247:Pregnancy; D013390:Succinylcholine; D013874:Thiopental
D008012:Lidocaine; D013390:Succinylcholine; D013874:Thiopental; D009609:Nitrous Oxide; D004837:Epinephrine