Stiff-man syndrome associated with nocturnal myoclonus and epilepsy.
A case of stiff-man syndrome associated with primary generalised epilepsy is reported. In addition, nocturnal polygraphic recording revealed a nocturnal myoclonus. Detailed examination of the central nervous system did not show specific changes. There is no direct proof as to a spinal or supraspinal origin of the stiff-man syndrome. The absence of specific anatomical lesions may indicate a functional rather than a structural disturbance in its physiopathogenesis.
D001921:Brain / Q000473:pathology / Q000503:physiopathology; D004569:Electroencephalography; D004576:Electromyography; D004827:Epilepsy / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009127:Muscle Rigidity / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D009132:Muscles / Q000503:physiopathology; D009207:Myoclonus / Q000150:complications* / Q000473:pathology; D012023:Reflex, Monosynaptic; D012890:Sleep; D013577:Syndrome