[Enzyme activity in post-infarct aneurysm and in the myocardial zone outside the infarct in experimental infarct in rats].
Activities of lactate dehydrogenase, glucose-6-phosphate dehydrogenase, transketolase and creatine phosphokinase were studied in tissue of aneurysm and in extrainfarctional part of rat heart muscle after experimental infarction. Activity of total LDH, content of its anode isoenzymes and creatine phosphokinase activity were decreased. Enzymes of pentose phosphate pathway were activated and amount of cathode LDH isoenzymes was increased. The most distinct and apparently irreversible alterations in the enzymatic activity were observed in the aneurysm tissues.
D000818:Animals; D003402:Creatine Kinase / Q000378:metabolism*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism*; D006322:Heart Aneurysm / Q000201:enzymology* / Q000209:etiology; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D009203:Myocardial Infarction / Q000150:complications / Q000201:enzymology*; D009206:Myocardium / Q000201:enzymology*; D051381:Rats; D014174:Transketolase / Q000378:metabolism*
D007770:L-Lactate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D014174:Transketolase; D003402:Creatine Kinase
Issledovanie aktivnosti nekotorykh fermentov anevrizmy i vneinfarktnoĭ zony miokarda krys posle éksperimental'nogo infarkta.