title: Differential diagnosis of sclerodermoid skin changes.
abstract: Sclerotic changes in the skin are most frequently caused by scleroderma. In those cases in which scleroderma is not implicated, careful historical, physical, histologic, and laboratory evaluation will allow an appropriate diagnosis to be made. In this way, appropriate therapy and prognostication can be given.
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis; D003937:Diagnosis, Differential; D006801:Humans; D008303:Malignant Carcinoid Syndrome / Q000473:pathology; D011164:Porphyrias / Q000175:diagnosis; D012592:Scleredema Adultorum / Q000175:diagnosis; D012594:Scleroderma, Localized / Q000175:diagnosis*; D012595:Scleroderma, Systemic / Q000175:diagnosis*; D012867:Skin / Q000473:pathology