Glycerin prevents the 'heat-death' of Ehrlich ascites tumor cells.
When heated to 45 degrees C for 20 min Ehrlich ascites tumor and NK-lymphoma cells are irreversibly damaged, so that they lose transplantability. The presence of 7-8% glycerol during heat treatment protects EAT cells completely and NK-lymphoma cells partly against this injury.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002286:Carcinoma, Ehrlich Tumor / Q000503:physiopathology*; D002470:Cell Survival / Q000187:drug effects; D005260:Female; D005990:Glycerol / Q000494:pharmacology*; D006358:Hot Temperature; D008223:Lymphoma / Q000503:physiopathology; D008297:Male; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000503:physiopathology; D014184:Transplantation, Homologous
D005990:Glycerol