[Interference by glutathione reductase in the "CK-MB-inhibition-test": elimination of the catalytic activity of glutathione reductase by anti-glutathione reductase (author's transl)].
Glutathione reductase interferes in the determiniation of creatine kinase-MB by the "CK-MB-inhibition-test". In 36 out of 55 serum samples with normal and elevated catalytic activities of creatine kinase, "negative" values greater than 14 U/l were obtained for the creatine kinase-MB. This interference by glutathione reductase is avoided by preincubation of the serum samples for 5 min with anti-glutathione reductase.
D002384:Catalysis; D002850:Chromatography, Gel; D004796:Clinical Enzyme Tests / Q000379:methods*; D003402:Creatine Kinase / Q000097:blood; D005980:Glutathione Reductase / Q000037:antagonists & inhibitors; D006801:Humans; D007202:Indicators and Reagents; D009203:Myocardial Infarction / Q000175:diagnosis
D007202:Indicators and Reagents; D005980:Glutathione Reductase; D003402:Creatine Kinase
Störung des "CK-MB-Hemmetestes" durch glutathion-Reduktase: Eliminierung der katalytischen Aktivit9at der Glutathion-Reduktase durch Anti-Glutathion-Reduktase.