title: Recurrent aphasia with subclinical bioelectric status epilepticus during sleep.
abstract: We present a six years follow up of a 6 1/2 year-old boy with recurrent aphasia, sporadic emotional regression and a convulsive disorder. The electroencephalogram reading during sleep showed continuous, generalized, hypersynchronous activity without clinical evidence of seizure ("subclinical bioelectric status epilepticus"). Clinical, laboratory and instrumental data revealed no evidence of a morphological lesion of the brain, either space-occupying, inflammatory, degenerative, or autoimmune. Remissions occured with and without anticonvulsant and steroid therapy. The hypothetical location, type, and etiology of the process are discussed. The syndrome appears to represent a functional disorganisation of speech-controlling areas of the brain.
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D001037:Aphasia / Q000150:complications* / Q000188:drug therapy; D002648:Child; D004569:Electroencephalography; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D012008:Recurrence; D012075:Remission, Spontaneous; D012890:Sleep; D013226:Status Epilepticus / Q000150:complications* / Q000188:drug therapy
chemical_list: D000927:Anticonvulsants; D011239:Prednisolone