The effect of vitamin B12 inhibition in vivo: impaired folate polyglutamate biosynthesis indicating that 5-methyltetrahydropteroylglutamate is not its usual substrate.
D013766:5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase / Q000037:antagonists & inhibitors*; D000818:Animals; D005492:Folic Acid / Q000031:analogs & derivatives* / Q000378:metabolism; D005971:Glutamates / Q000378:metabolism; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D051379:Mice; D009609:Nitrous Oxide / Q000494:pharmacology*; D014805:Vitamin B 12 / Q000037:antagonists & inhibitors*
D005971:Glutamates; D005492:Folic Acid; D008780:Methyltransferases; D013766:5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; D009609:Nitrous Oxide; D014805:Vitamin B 12