Prenatal endogenous androgenic influences on masculine sexual behavior and genital morphology in male and female rats.
Female rats located near a male during uterine development showed increased frequencies of male-like behavior as adults and virilization of genital morphology. These changes in behavior and morphology were blocked by prenatal treatment with the anti-androgen, Flutamide.
D000728:Androgens / Q000378:metabolism / Q000494:pharmacology / Q000502:physiology*; D000818:Animals; D003307:Copulation; D005260:Female; D005333:Fetus / Q000187:drug effects / Q000502:physiology*; D005485:Flutamide / Q000494:pharmacology; D005835:Genitalia / Q000033:anatomy & histology*; D005836:Genitalia, Female / Q000033:anatomy & histology; D005837:Genitalia, Male / Q000033:anatomy & histology; D008297:Male; D051381:Rats; D012726:Sexual Behavior, Animal / Q000187:drug effects*
D000728:Androgens; D005485:Flutamide