Radionuclide angiography for the evaluation of anthracycline therapy.
A sensitive and reproducible method to noninvasively monitor cardiac function in patients receiving anthracycline therapy is badly needed. The radionuclide ejection fraction (EFrn) appears to be a suitable technique to provide this hemodynamic information. This paper describes the technique for determining the left ventricular EFrn with the use of technetium99m-labeled rbcs, a gamma scintillation camera, and a dedicated computer. The comparison of radionuclide and radiographic contrast EFrn showed a high correlation ( r = 0.84) in 30 patients.
D000792:Angiography / Q000379:methods; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D006331:Heart Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D011877:Radionuclide Imaging; D013667:Technetium
D000903:Antibiotics, Antineoplastic; D013667:Technetium