[Lung tissue alterations following experimental infection of mice with acholeplasmae isolated from simians with hematosarcoma].
This paper is devoted to the study of pathogenic acholeplasmae potencies. Two strains of acholeplasmae isolated from the blood and organs of Papio hamadryas suffering from hemoblastosis and a standard Ach. laidlawii A. strain were subjected to the comparative study with the use of a "pulmonary model" in experiments on mice. Morphological investigations showed affections of the pulmonary tissue characterized by stage-by-stage inflammatory-destructive changes analogous to the lesions found in "mycoplasmosis of the lungs". Prolonged inflammatory changes in the pulmonary tissue were maintained by a long-term persistence of acholeplasmae in it. A conclusion was drawn that acholeplasmae isolated from monkeys suffering from hematosarcoma had marked pathogenic action on the pulmonary tissue of mice. Strain differences in the pathogenic activity of the strains under study were revealed.
D000127:Acholeplasma / Q000302:isolation & purification*; D000128:Acholeplasma laidlawii; D000818:Animals; D008168:Lung / Q000473:pathology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009175:Mycoplasma Infections / Q000473:pathology*; D012513:Sarcoma, Experimental / Q000382:microbiology*
Izmeneniia legochnoĭ tkani pri éksperimental'nom zarazhenii mysheĭ akholeplazmami, vydelennymi ot obez'ian s gematosarkomoĭ.