[Production of interferon and virus-neutralizing antibodies in adult mice infected with enteroviruses during the neonatal period].
Newborn albino mice were inoculated with enteroviruses and in 6 weeks reinfected with homologous or heterologous strains. Strains moderately pathogenic for newborn mice led to formation of specific immunologic memory. Mice infected after birth with highly pathogenic strains produced specific antibodies for a long time and lacked secondary response. Production of interferon was not associated either with the strain pathogenicity for newborn mice or with the presence of antibodies.
D000818:Animals; D000831:Animals, Newborn / Q000382:microbiology; D000914:Antibodies, Viral / Q000096:biosynthesis*; D003384:Coxsackievirus Infections / Q000276:immunology; D004457:Echovirus Infections / Q000276:immunology; D004770:Enterovirus / Q000276:immunology*; D029822:Enterovirus B, Human / Q000276:immunology*; D007156:Immunologic Memory; D007372:Interferons / Q000096:biosynthesis*; D051379:Mice
D000914:Antibodies, Viral; D007372:Interferons
Produktsiia interferona i virus-neĭtralizuiushchikh antitel u vzroslykh mysheĭ, zarazhennykh v neonatal'nyĭ period enterovirusami.