Kinetic and mechanistic studies of blue tetrazolium reaction with phenylhydrazines.
The reaction kinetics of blue tetrazolium with selected arylhydrazines were investigated under pseudo-first-order conditions. The reaction rate constants were obtained at various temperatures, and the enthalpy (8.4-11.2 kcal/mole) and entropy (-38--45 eu) of activations were calculated. A Hammett plot yielded a straight line with a slope of 0.52. The reaction was inhibited by atmospheric oxygen and iodine. A free radical mechanism is presented.
D055598:Chemical Phenomena; D002621:Chemistry; D007455:Iodine; D010084:Oxidation-Reduction; D010100:Oxygen; D010659:Phenylhydrazines; D013778:Tetrazolium Salts
D010659:Phenylhydrazines; D013778:Tetrazolium Salts; D007455:Iodine; D010100:Oxygen