Genetic basis of susceptibility for development of neoplasms following treatment with N-methyl-N-nitrosourea (MNU) or x-rays in the platyfish/swordtail system.
Specific genotypes of the xiphophorine fish develop neoplasms following treatment with N-methyl-N-nitrosourea or X-rays. Several of these neoplasms can be related to the presence of specific chromosomes. The implication of these findings are discussed.
D000818:Animals; D002875:Chromosomes; D005260:Female; D005399:Fishes / Q000235:genetics*; D005838:Genotype; D008297:Male; D008770:Methylnitrosourea; D009154:Mutation; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000235:genetics*; D009381:Neoplasms, Radiation-Induced / Q000235:genetics*
D008770:Methylnitrosourea