Transplantation of bovine odontogenic tissues and dissociated odontogenic cells to hypothymic mice.
It was demonstrated in this study that bovine odontogenic tissues and the dissociated cell preparations of such tissues, when transplated to the subcapsular kidney site of hypothymic mice, retained their phenotypic expression and continued function to produce their recognisable products, dentine and enamel matrices. It was also shown that in the grafts of dissociated odontogenic tissues, cell sorting occurred so that histotypical tissues were formed and that their function produced readily recognisable dentine and enamel matrices. Attention has been drawn to the usefulness of this model for studying a variety of events that occur during odontogenesis.
D000818:Animals; D002417:Cattle; D005260:Female; D006085:Graft Survival; D007668:Kidney / Q000601:surgery*; D051379:Mice; D008819:Mice, Nude / Q000276:immunology*; D009805:Odontogenesis; D010641:Phenotype; D014083:Tooth Germ / Q000637:transplantation* / Q000648:ultrastructure; D014183:Transplantation, Heterologous