Mechanism of fixation of two-loop iridocapsular lenses.
I used seven eyes obtained postmortem to study the mechanism of fixation of a Binkhorst two-loop iridocapsular lens. During the first postoperative weeks, vitreous pressure and traction on the posterior lens capsule exerted by the zonular fibers pushed the loops of the iridocapsular lens against the iris. The zonular traction maintained the posterior capsule taut so that the vitreous pressure was distributed equally over the entire surface of the capsular diaphragm. Lens epithelial cells proliferated around the margin of the capsular breaks and defects and formed plaques or masses of spindle-shaped cells. This pseudofibrous tissue bridged and sealed capsular defects and caused adhesions between the anterior and posterior lens capsule and between the anterior capsule and the iris pigment epithelium. Fixation of the lenses may be reinforced by proliferation of the iris pigment epithlium and of the fibrous tissue arising from the iris stroma.
D006801:Humans; D007498:Iris / Q000473:pathology / Q000601:surgery; D007908:Lens, Crystalline / Q000473:pathology / Q000601:surgery; D007909:Lenses / Q000592:standards; D019736:Prostheses and Implants