title: 21-Hydroxypregna-1,4-diene-3,11,20-trione: a biliary metabolite of a cartilaginous fish, Raja sp.
abstract: 21-Hydroxypregna-1,4-diene-3,11,20-trione was isolated from skate bile and as an in vivo metabolite of 3H-1alpha-hydroxycorticosterone. Identity was established by chromatography and derivatization to constant 3H/14C ratio and mass spectrometry of the 20,21-acetonide. The new steroid was present in the free form and as the glucuronoside.
mesh_terms: D000818:Animals; D001646:Bile / Q000032:analysis*; D003345:Corticosterone / Q000031:analogs & derivatives / Q000378:metabolism; D005399:Fishes; D007664:Ketosteroids / Q000032:analysis; D013058:Mass Spectrometry; D011245:Pregnadienes / Q000032:analysis*
chemical_list: D007664:Ketosteroids; D011245:Pregnadienes; C017415:21-hydroxypregna-1,4-diene-3,11,20-trione; D003345:Corticosterone