Congenital hydrocephalus and cerebellar agenesis.
In a sibship of three brothers, two expired shortly after birth with congenital hydrocephalus, and necropsy of one revealed cerebellar agenesis and absence of the foramina of Luschka and Magendie. The non-specificity of the Dandy-Walker anomaly is discussed, and it is suggested that the present patients demonstrate another form of heritable hydrocephalus, possibly on an X-linked recessive basis.
D002531:Cerebellum / Q000002:abnormalities* / Q000473:pathology; D006801:Humans; D006849:Hydrocephalus / Q000235:genetics* / Q000473:pathology; D007231:Infant, Newborn; D008297:Male; D010375:Pedigree