Amino acid sequence of the Fc region of a canine immunoglobulin M: interspecies homology for the IgM class.
The amino acid structure for the Fc portion of a canine immunoglobulin mu chain was determined. The sequence was compared with those of two human mu chains, and a high degree of interspecies homology was observed. The preservation of primary structure between species is probably reflective of the unique functions associated with the immunoglobulin M class.
D000595:Amino Acid Sequence; D000818:Animals; D005075:Biological Evolution; D004285:Dogs; D006801:Humans; D007141:Immunoglobulin Fc Fragments; D007075:Immunoglobulin M; D013045:Species Specificity
D007141:Immunoglobulin Fc Fragments; D007075:Immunoglobulin M