title: Effect of cortisone or triiodothyronine administration to pregnant rats on lysosomal hydrolases in fetal forebrain and cerebellum.
abstract: Triiodothyronine injected daily to pregnant rats for the last week of gestation (50 microgram/100 g b.wt) increased the specific activities of 5 acid glycosidases in the fetal forebrain and cerebellum. Cortisone (50 mg/100 g b.wt) administered in the same period had no effect on cerebellum acid hydrolases, but decreased their activity in the forebrain.
mesh_terms: D000818:Animals; D001921:Brain / Q000196:embryology / Q000201:enzymology*; D002531:Cerebellum / Q000201:enzymology; D003348:Cortisone / Q000494:pharmacology*; D005260:Female; D005333:Fetus / Q000201:enzymology*; D006026:Glycoside Hydrolases / Q000378:metabolism*; D008247:Lysosomes / Q000201:enzymology; D011247:Pregnancy; D051381:Rats; D014284:Triiodothyronine / Q000494:pharmacology*
chemical_list: D014284:Triiodothyronine; D006026:Glycoside Hydrolases; D003348:Cortisone