Antitumor of a boiled scallop extract.
A fraction from a boiled scallop extract modified by a sonication procedure exhibited marked antitumor activity when it was injected intradermally into either ICR or C3H/He mice that had been given sc implants of sarcoma 180 and Ehrlich carcinoma. The active moiety was heat-stable and noncytotoxic. In contrast, preparations from raw scallop showed lower antitumor activity and were heat-labile.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000628:therapy; D007167:Immunotherapy; D051379:Mice; D008815:Mice, Inbred Strains; D008974:Mollusca / Q000276:immunology*; D009374:Neoplasms, Experimental / Q000628:therapy*; D012510:Sarcoma 180 / Q000628:therapy