Theophylline half-life in infants and young children.
Pharmacokinetics of theophylline elimination were studied in a 54-child population. Subjects' ages ranged from three months to six years. The mean half life was 4.92 hours, with S.D. +/- 1.88 hours. This is at variance with previous reports. Ages and half lives were compared and there were no correlations in this young age group.
D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D006207:Half-Life; D006801:Humans; D007223:Infant; D013806:Theophylline / Q000494:pharmacology*
D013806:Theophylline