Taste preference test for oral liquid theophylline preparations.
Taste preferences among three oral liquid theophylline preparations were evaluated in 54 males. The products tested, and their theophylline concentrations, were Elixophyllin Pediatric Suspension (Cooper Laboratories, Inc.), 100 mg/5 ml; Somophyllin Oral Liquid (Fisons Corporation), 90 mg/5 ml; and Theophyl-225 Elixir (Knoll Pharmaceutical Company), 37.5 mg/5 ml. Generally-recommended procedures for taste tests were followed. The results indicated a taste preference for Theophyl-225 Elixir, followed by Elixophyllin Pediatric Suspension, followed by Somophyllin Oral Liquid. The results were statistically significant (p = 0.05). Product concentration and formulation were suggested to be major factors in determining taste preference.
D000284:Administration, Oral; D000328:Adult; D006801:Humans; D008297:Male; D008722:Methods; D012996:Solutions; D013535:Suspensions; D013649:Taste; D013806:Theophylline
D012996:Solutions; D013535:Suspensions; D013806:Theophylline