Metabolism of papaverine IV. Urinary elimination of papaverine metabolites in man.
1. A gas chromatographic method is described for the quantitative determination of the metabolites of papaverine in urine. 2. The urinary excretion of papaverine metabolites was studied in man. About 50% of the metabolites of papaverine are excreted in the urine within 48 h. 6-Desmethylpapaverine is the major metabolite in the urine. The metabolites are excreted almost completely in conjugated form.
D001711:Biotransformation; D002849:Chromatography, Gas; D006801:Humans; D010208:Papaverine / Q000652:urine*; D013997:Time Factors
D010208:Papaverine