IgA nephropathy: clinicopathology and immunopathology.
In a total of 283 biopsies, 100 (35%) were found to be IgA nephropathy. The incidence reached 40% among primary glomerulonephropathies. On the basis of histopathologic changes in glomeruli, these biopsies were classified into 3 groups. The criteria employed correlated well with clinical, laboratory and immunofluorescent findings. Immune complex pathogenesis was discussed in relation to our findings.
D000293:Adolescent; D000328:Adult; D002648:Child; D003165:Complement System Proteins / Q000032:analysis; D005260:Female; D005921:Glomerulonephritis / Q000276:immunology / Q000473:pathology*; D006023:Glycoproteins / Q000032:analysis; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007678:Kidney Glomerulus / Q000276:immunology / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D011414:Properdin / Q000032:analysis
D006023:Glycoproteins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011414:Properdin; D003165:Complement System Proteins