Repair of UV-induced damage in wild-type and mutant strains of Schizophyllum commune.
The basidiomycete fungus Schizophyllum commune was found to have both photo-repair and dark-repair systems for UV-induced damage. Three UV-sensitive mutants were isolated and characterized for ability to repair UV-induced damage in light and dark, and for cross-sensitivity to caffeine and methyl methanesulfonate. Two of the mutants were damaged, to different extents, in their capacity for excision repair; one of these mutants was also probably damaged in post-replication repair. The third mutant was damaged only in post-replication repair.
D002110:Caffeine / Q000494:pharmacology; D004247:DNA / Q000528:radiation effects*; D004260:DNA Repair / Q000187:drug effects; D008027:Light; D008741:Methyl Methanesulfonate / Q000494:pharmacology; D009154:Mutation; D012567:Schizophyllum / Q000235:genetics / Q000528:radiation effects; D014466:Ultraviolet Rays
D002110:Caffeine; D004247:DNA; D008741:Methyl Methanesulfonate