title: [Polychemotherapy of advanced cancer of the breast].
abstract: Results obtained with a cyclophosphamide, methotrexate, vincristine, 5-FU and prednisone protocol in the treatment of advanced breast cancer are reported. The number of weekly courses proposed by Ansfield was varied. 53% remissions were noted. The effect of the variation introduced was assessed with reference to a much lower incidence of side-effects and a percentage of satisfactory results comparable with that of Ansfield. Nevertheless, it is felt that the treatment in question should be employed as a second choice when more efficacious protocols, such as those including adriamycin, cannot be used or have proved ineffective.
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D000970:Antineoplastic Agents; D014750:Vincristine; D003520:Cyclophosphamide; D005472:Fluorouracil; D011241:Prednisone; D008727:Methotrexate
vernacular_title: Polichemioterapia del cancro avanzato della mammella.