title: [The recessive Hm phenotypes].
abstract: The survival of "Bombay" erythrocytes as well as that of "para Bombay" red cells (first and third class according to Race and Sanger classification) has been studied among non compatible and "para Bombay" individuals. This shows not only the heterogeneity of these phenotypes (as already described by Salmon and co workers) but also the presence of highly differenciated ABH formed antigens. H deficient recessive phenotypes are not explained by the presence of an amorphe h gene. They arise from the activity (or better from the non activity) of the regulation genes of which the recessive alleles x and z in double dose do not enable a normal functioning of the H gene. The appelation Hxx for "Bombay" phenotypes (1st classe) and the appelation Hzz for Hm recessive (3d. class) phenotypes are proposed. Genetics as well as the synthesis of Ah, Bh (AHm, BHm) phenotypes have not yet been clarified. Interaction of zz and sese genes, or accomplementation in the "trans" position have to be looked at.
mesh_terms: D000017:ABO Blood-Group System; D000328:Adult; D001666:Binding Sites, Antibody; D001789:Blood Group Antigens; D005260:Female; D005808:Genes, Recessive; D005809:Genes, Regulator; D006801:Humans; D008297:Male; D010641:Phenotype; D011247:Pregnancy; D009626:Terminology as Topic
chemical_list: D000017:ABO Blood-Group System; D001789:Blood Group Antigens
vernacular_title: Les phénotypes Hm récessifs.