title: [Influence of furosemide on beta-methyl-digoxin excretion in the urine (author's transl)].
abstract: Ten patients were given 0.1 mg, ten other patients 0.2 mg beta-methyl-digoxin in a daily dose for 14 days. Furosemide (80 mg a single daily dose) was given on the 12th, 13th and 14th day of digoxin treatment. Furosemide had no significant effect on blood-serum levels of the digoxin preparations, nor on its urinary excretion. Urinary excretion and serum levels of beta-methyl-digoxin remained unchanged both after simultaneous administration of furosemide with the digoxin and when furosemide was given ten hours after the last digoxin dose.
mesh_terms: D000328:Adult; D000368:Aged; D004077:Digoxin / Q000031:analogs & derivatives* / Q000097:blood / Q000627:therapeutic use / Q000652:urine*; D004347:Drug Interactions; D005260:Female; D005665:Furosemide / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D008297:Male; D008875:Middle Aged
chemical_list: D004077:Digoxin; D005665:Furosemide
vernacular_title: Der Einfluss von Furosemid auf die beta-methyl-digoxin-ausscheidung im Urin.