[A case of lithium intoxication at therapeutic lithium dosage due to additional diuretic therapy (author's transl)].
A case is presented of lithium intoxication with therapeutic doses of lithium, owing to the additional administration of a sodium-excreting diuretic. Since the patient was receiving neuroleptic therapy at the same time, intoxication symptoms at the onset were falsely attributed to neuroleptic extrapyramidal effects. The possible effects of widely-used diuretics in conjunction with lithium therapy are presented. The combination of both therapeutic substances is possible, but calls for extreme caution and strict control of medication, diet and serum lithium levels.
D000584:Amiloride / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy*; D004338:Drug Combinations; D004347:Drug Interactions; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use; D008094:Lithium / Q000097:blood / Q000506:poisoning* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012964:Sodium / Q000097:blood
D004338:Drug Combinations; D006852:Hydrochlorothiazide; D000584:Amiloride; D008094:Lithium; D012964:Sodium; D006220:Haloperidol
Ein Fall von Lithiumintoxikation bei therapeutischen Lithiumdosen infolge zusätzlicher Gabe eines Diuretikums.