title: [Melanin granule metabolism in the iris and retinal pigment epithelium in adult tritions after completion of eye regeneration].
abstract: It was concluded that the newly synthesized melanin granules were replaced in the pigmented tissues of the newt eye on the basis of redistribution of the cells of pigment epithelium of retina and iris labelled by 3H-DOPA 2.5 and 6.5 months after the isotope injection. The replacement of melanin granules and, correspondingly, melanin synthesis proceed more actively in the peripheral zones of the pigment epithelium of retina. The depigmentation of cells preceding the melanin synthesis appears to be realized with the participation of macrophages.
mesh_terms: D000818:Animals; D004295:Dihydroxyphenylalanine / Q000378:metabolism; D007498:Iris / Q000378:metabolism*; D008543:Melanins / Q000096:biosynthesis / Q000378:metabolism*; D009799:Ocular Physiological Phenomena; D010857:Pigment Epithelium of Eye / Q000378:metabolism*; D012038:Regeneration; D013997:Time Factors; D014319:Triturus / Q000378:metabolism*
chemical_list: D008543:Melanins; D004295:Dihydroxyphenylalanine
vernacular_title: Obmen melaninovykh granul v raduzhine i pigmentnom épitelii setchatki u vzroslykh tritonov posle zaversheniia regeneratsii glaza.