Bayliss myogenic response in the isolated ductus arteriosus of guinea-pig and rabbit fetuses.
Isolated ductus arteriosus responds by marked constriction to increases in perfusion pressure. If, however, these increases exceed 90 mm Hg-130 mm Hg, the vessel suddenly dilates and its responsiveness becomes depressed. The importance of these findings in postnatal closure of ductus arteriosus is discussed.
D000818:Animals; D004373:Ductus Arteriosus / Q000502:physiology*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D010100:Oxygen / Q000097:blood; D010477:Perfusion; D011312:Pressure; D051381:Rats; D014661:Vasoconstriction; D014664:Vasodilation
D010100:Oxygen