[Nature of the sensitizing influence of urea on the effects of catecholamines].
Tests conducted on aortic strips of rabbits, portal veins and musculus rectococcygeus in rats showed the urea to nonspecifically increase the effects of norepinephrine at the expense of a greater calcium permeability of membranes and, possibly, also at the expense of a higher sensitivity of the myosin adenosine-triphosphatase to the action of calcium ions without affecting the function of adrenoreceptors.
D000818:Animals; D002395:Catecholamines / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects; D009129:Muscle Tonus / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D011817:Rabbits; D014508:Urea / Q000494:pharmacology*
D002395:Catecholamines; D014508:Urea
O prirode sensibiliziruiushchego vliianiia mocheviny na éffekty katekholaminov.