title: [Treatment of distortions and non-traumatic conditions of pain and swelling. Double-blind trial with an analgetic and detumescent drug combination].
abstract: A combination of specifically detumescent and analgesic/antiphlogistic substances (Dolo Mobilat film tablets) was tested in a double-blind study against placebo. The active product brought about very good or good therapeutic results in approximately 78% of 50 patients suffering from distortions of joints and from painful inflammation and swelling of non-traumatic origin; the  corresponding percentage obtained with the placebo was 34%. Separate evaluations of pain and swellings most relevant for their homogeneity in distortions of joints showed rates of 80% and 31%, respectively. These differences as to efficacy are highly significant (p less than 0.001). There were no symptoms of intolerance except some sporadic mild gastric complaints. In comparison with the experience made with analgesics and antiphlogistics in oral therapy the action and tolerance were judged as very good.
mesh_terms: D000082:Acetaminophen / Q000627:therapeutic use*; D000328:Adult; D004311:Double-Blind Method; D004338:Drug Combinations; D004357:Drug Synergism; D004487:Edema / Q000188:drug therapy*; D006801:Humans; D007592:Joint Diseases / Q000188:drug therapy; D010146:Pain / Q000188:drug therapy*; D010656:Phenylephrine / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D010656:Phenylephrine; D000082:Acetaminophen
vernacular_title: Zur Behandlung von Distorsionen und nicht-traumatisch bedingten Schmerz-und Schwellungszuständen Doppelblind-Versuch mit einer analgetisch und abschwellend wirksamen Substanz-Kombination.