[Hematopoietic indices in rats with sarcoma 45 in the process of treatment with cytostatics and diuretic agents].
Sarcoma 45 growth in rats was noted to be followed by the development of anemia and leucocytosis. Sessional use of 6-mercaptopurine and cyclophosphane resulted in the enhancement of anemia, the development of leucopenia, and suppression of bone marrow hemopoiesis. The suppression of hemopoiesis was much less manifested, if cytostatics were used together with diuretics (diacarbe or furocemid).
D000086:Acetazolamide / Q000627:therapeutic use; D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D005665:Furosemide / Q000627:therapeutic use; D006410:Hematopoiesis / Q000187:drug effects*; D015122:Mercaptopurine / Q000627:therapeutic use; D051381:Rats; D012513:Sarcoma, Experimental / Q000188:drug therapy* / Q000503:physiopathology
D000970:Antineoplastic Agents; D004232:Diuretics; D005665:Furosemide; D003520:Cyclophosphamide; D015122:Mercaptopurine; D000086:Acetazolamide
Pokazateli krovetvoreniia u krys s sarkomoĭ 45 v protsesse lecheniia tsitostatikami i mochegonnymi sredstvami.