title: Inhibition of the efflux of organic ions from renal cortical slices.
abstract: Cyanine 863 inhibited the efflux of tetraethylammonium ion from slices of rat or rabbit renal cortex while the efflux of p-aminohippuric acid was unaffected. Dinitrophenol increased the efflux rate of both the cation and anion. Cyanine also decreased the dinitrophenol-enhanced efflux of tetraethylammonium (TEA).
mesh_terms: D000618:Aminohippuric Acids / Q000378:metabolism*; D000818:Animals; D004396:Coloring Agents / Q000494:pharmacology; D004140:Dinitrophenols / Q000494:pharmacology; D005260:Female; D007672:Kidney Cortex / Q000187:drug effects / Q000378:metabolism*; D011743:Pyrimidines / Q000494:pharmacology; D011806:Quinolinium Compounds / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D013757:Tetraethylammonium Compounds / Q000378:metabolism*
chemical_list: D000618:Aminohippuric Acids; D004396:Coloring Agents; D004140:Dinitrophenols; D011743:Pyrimidines; D011806:Quinolinium Compounds; D013757:Tetraethylammonium Compounds; C016855:cyanine 863