Bronchodilating effect of terbutaline aerosol.
We compared the efficacy of terbutaline with that of metaproterenol, isoproterenol, and placebo aerosols in 16 asthmatic patients. Terbutaline, metaproterenol, and isoproterenol produced equivalent improvements in flow rates. At 5 hr, the effect of terbutaline on tests of small airways, FEF25%--75%, and FEF50%, was greater (p less than 0.05) than that of metaproterenol and isoproterenol. Terbutaline produced no significant change of heart rate or blood pressure.
D000328:Adult; D000336:Aerosols; D001993:Bronchodilator Agents; D005260:Female; D006801:Humans; D007545:Isoproterenol / Q000008:administration & dosage / Q000494:pharmacology; D008297:Male; D009921:Metaproterenol / Q000008:administration & dosage / Q000494:pharmacology; D008875:Middle Aged; D013726:Terbutaline / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors
D000336:Aerosols; D001993:Bronchodilator Agents; D009921:Metaproterenol; D007545:Isoproterenol; D013726:Terbutaline