Effects of isoniazid (INH) on the oogenesis of mice.
Mutagenic damages in female germ cells of mice have been tested with the dominant lethal assay and the cytogenetic analysis of unfertilized M II-oocytes. Concluding one can say that from the experimental data presented here do not show any mutagenic effect of INH on oogenesis of different strains of mice can be stated.
D000818:Animals; D002869:Chromosome Aberrations; D005260:Female; D007538:Isoniazid / Q000494:pharmacology*; D051379:Mice; D009865:Oocytes / Q000187:drug effects; D009866:Oogenesis / Q000187:drug effects*; D013997:Time Factors
D007538:Isoniazid