[Motor activity and the prevention of the sequelae of hypokinesia (according to tissue metabolic indices)].
The content of protein, DNA and RNA was measured in rats that had been exposed to 90-day hypokinesia: hypokinesia alternating with unrestrained maintenance and hypokinesia combined with exercises (swimming). Adverse effects of hypokinesia on metabolism seemed to build up. Short-term passive rest was insufficient to make up deficiency in motor activity. The recovery of metabolic disorders after prolonged hypokinesia proceeded in a non-uniform and slow manner: most parameters did not return to the initial level within one month. During the first two weeks exercises produced effects similar to those of hypokinesia. By the 30th and 60th days they shower their normalizing effect on tissue metabolism. When developing work-rest cycles for the people who are exposed to partial hypokinesia during work and do exercises as a countermeasure against hypokinetic effects, biochemical analysis of blood (nonesterified fatty acids, acetone bodies, cholesterol, beta-lipoproteins, urea) and urine (potassium, calcium, creatinine) should be made to measure metabolic processes in tissues.
D000818:Animals; D004247:DNA / Q000378:metabolism*; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D011506:Proteins / Q000378:metabolism*; D012313:RNA / Q000378:metabolism*; D051381:Rats; D012149:Restraint, Physical / Q000009:adverse effects*; D013550:Swimming; D013997:Time Factors
D011506:Proteins; D012313:RNA; D004247:DNA
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