The treatment of pleuropulmonary amebiasis with metronidazole.
One hundred forty patients with pleuropulmonary amebiasis were classified radiographically in order to rationalize therapy based on the use of metronidazole. Amebic testing with gel diffusion, serial chest x-ray films, and observation of the patient's response to treatment have dominated management of the patients, 135 of whom made a successful recovery. Five patients died. Sixty percent of the surviving patients have been reviewed at a follow-up clinic, and there has been no instance of recurrence of amebiasis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000562:Amebiasis / Q000188:drug therapy* / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D004653:Empyema / Q000188:drug therapy / Q000601:surgery; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy*; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D008875:Middle Aged; D010995:Pleural Diseases / Q000188:drug therapy*; D010996:Pleural Effusion / Q000188:drug therapy
D008795:Metronidazole