title: [Participation of the H-2 system in regulating the sensitivity of mice to morphine].
abstract: The pain susceptibility of congenic-resistant mouse strains A/Sn, C3H/Sn and C57BL/10 Sn after the injection of morphine was studied. Strains sensitive and resistant to this narcotic were distinguished among congenic-resistant A/Sn and C3H/Sn mice. The morphine sensitivity inheritance is characterized by dominance. The possibility of the major histocompatibility mouse system (H-2) participation in the genetic control of mouse susceptibility to morphine is discussed.
mesh_terms: D000818:Animals; D004351:Drug Resistance; D005796:Genes; D005799:Genes, Dominant; D006183:H-2 Antigens; D006824:Hybridization, Genetic; D051379:Mice; D008815:Mice, Inbred Strains; D009020:Morphine / Q000494:pharmacology*; D013045:Species Specificity
chemical_list: D006183:H-2 Antigens; D009020:Morphine
vernacular_title: Uchastie sistemy H-2 v reguliatsii chuvstvitel'nosti mysheĭ k morfinu.