Benzomorphans. Structure of a position isomer.
May's benzomorphan synthesis leads not only to the alpha or cis isomer and the beta or trans isomer but also to a position isomer hereinafter called the gamma isomer. The structure and synthesis of this isomer are described. Biological activities of the alpha and gamma isomers are compared.
D000818:Animals; D001575:Benzomorphans / Q000031:analogs & derivatives / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D007536:Isomerism; D009019:Morphinans / Q000031:analogs & derivatives / Q000494:pharmacology; D009292:Narcotic Antagonists; D009294:Narcotics; D051381:Rats; D013329:Structure-Activity Relationship
D001575:Benzomorphans; D009019:Morphinans; D009292:Narcotic Antagonists; D009294:Narcotics