Light scattering measurements supporting helical structures for chromatin in solution.
Laser light scattering measurements have been made on a series of polynucleosomes containing from 50 to 150 nucleosomes. Radii of gyration have been determined as a function of polynucleosome length for different ionic strength solutions. The results suggest that at low ionic strength the chromatin adopts a loosely helical structure rather than a random coil. The helix becomes more regular on increasing the ionic strength, the dimension resembling those proposed by Finch and Klug for their solenoid model.
D000818:Animals; D002467:Cell Nucleus; D002645:Chickens; D002843:Chromatin; D004912:Erythrocytes; D008027:Light; D009690:Nucleic Acid Conformation; D011487:Protein Conformation; D012542:Scattering, Radiation
D002843:Chromatin