[Effect of theophylline and isoprenaline on N-acetylation activity in the rat liver].
The activity of N-acetyltransferase is shown to significantly rise after administration of theophylline and isoprenaline, but not of propranolol and N-acetylderivate of para-aminosalicylic acid to form during 30 minutes at a constant rate that increases following addition of cyclic AMP to the incubation medium. The capacity of the rat to acetylate paraaminosalicylic acid did not change under the effect of the mentioned agents.
D000107:Acetylation; D000123:Acetyltransferases / Q000378:metabolism; D010131:Aminosalicylic Acid / Q000378:metabolism; D000818:Animals; D004789:Enzyme Activation / Q000187:drug effects; D005260:Female; D007545:Isoproterenol / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D013806:Theophylline / Q000494:pharmacology*; D013997:Time Factors
D010131:Aminosalicylic Acid; D011433:Propranolol; D013806:Theophylline; D000123:Acetyltransferases; D007545:Isoproterenol
Vliianie teofillina i izoprenalina na aktivnost' N-atsetilirovaniia v pecheni krysy.