[Inappropriate secretion of anti-diuretic hormone in a case of intermittent acute porphyria (author's transl)].
The authors report the case of a patient who presented, during two exacerbations of intermittent acute porphyria, a grave psychiatric syndrome secondary to severe hyponatraemia. The later was due to inappropriate secretion of anti-diuretic hormone confirmed by laboratory tests and the stimation of anti-diuretic activity in the urine. The course was favourable under the effects of symptomatic treatment including sodium supplements and fluid restriction. The anti-diuretic syndrome disappeared on each occasion without sequelae at the time of regression of the exacerbation of porphyria.
D000208:Acute Disease; D007010:Hyponatremia / Q000209:etiology; D011164:Porphyrias / Q000150:complications* / Q000378:metabolism; D012008:Recurrence; D014667:Vasopressins / Q000378:metabolism* / Q000652:urine
D014667:Vasopressins
Sécrétion inappropriée d'hormone anti-diurétique au cours d'une porphyrie aiguë intermittente.