The location of the globin mRNA sequence within its 16S precursor.
The coding sequence of globin mRNA has been located at or very close to the 3' end of its poly(A)-containing 16S precursor. The 16S RNA was annealed to globin cDNA and the hybrid digested with ribonuclease H. The undigested fragment did not bind to oligo(dT)-cellulose and its size was that expected for the intact 5' portion of the precursor.
D000818:Animals; D001483:Base Sequence; D005914:Globins / Q000235:genetics*; D051379:Mice; D009693:Nucleic Acid Hybridization; D009694:Nucleic Acid Precursors / Q000235:genetics* / Q000302:isolation & purification; D012333:RNA, Messenger / Q000235:genetics*
D009694:Nucleic Acid Precursors; D012333:RNA, Messenger; D005914:Globins