title: Direct deposition autoradiography: can it really be detecting radioactivity?
abstract: The literature concerning the 'direct deposition method' of electron microscope autoradiography has been examined and certain calculations made. Studies have been made on the interaction of gold chloride with protein films, tissue sections and ultrathin sections. It is concluded that in its present form the direct deposition method does not offer an autoradiographic approach of practical value.
mesh_terms: D000818:Animals; D001345:Autoradiography / Q000379:methods*; D002250:Carbon Radioisotopes; D004848:Epithelium / Q000378:metabolism; D004947:Esophagus / Q000378:metabolism; D006046:Gold; D007633:Keratins / Q000378:metabolism; D008027:Light; D008099:Liver / Q000378:metabolism; D008854:Microscopy, Electron; D011506:Proteins / Q000378:metabolism; D051381:Rats
chemical_list: D002250:Carbon Radioisotopes; D011506:Proteins; D007633:Keratins; D006046:Gold