title: Manganese status of pasturing ewes, of pregnant ewes and doe rabbits on low manganese diets and of dairy cows with cystic ovaries.
abstract: Four experiments were conducted to obtain information on the manganese (Mn) status of ewes, doe rabbits and dairy cows with cystic ovaries. Manganese was not concentrated specifically in any one tissue or organ but the use of 54Mn has indicated that the isotope was retained by the liver for a longer time. Significantly lower (P less than 0.01) levels of Mn were observed in the liver, kidney and blood of pregnant ewes fed a synthetic diet containing low levels (5 ppm) of Mn than those that were supplemented with 60 ppm Mn. It would appear that the determination of blood Mn concentration would provide a valuable diagnostic tool for the assessment of the Mn status of the pregnant ewe and could be more reliable than data based on tissue (liver, kidney, ovary) levels of Mn. The cortical stroma of dairy cows with cystic ovaries had lower Mn contents than those cows that were without cystic ovaries. The data on blood suggests that cystic ovaries cannot be diagnosed by blood Mn levels if Mn was indeed a contributing factor of the development of this condition. The doe rabbit responded to supplemental dietary Mn in a manner analogous to the ewes.
mesh_terms: D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000662:veterinary*; D005260:Female; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008345:Manganese / Q000097:blood / Q000172:deficiency / Q000378:metabolism*; D010048:Ovarian Cysts / Q000378:metabolism / Q000662:veterinary*; D010053:Ovary / Q000378:metabolism; D010179:Pancreas / Q000378:metabolism; D011247:Pregnancy; D011270:Pregnancy, Animal; D011817:Rabbits / Q000378:metabolism*; D012756:Sheep / Q000378:metabolism*
chemical_list: D008345:Manganese