Human somatic chromosome chains and rings. A preliminary note on end-to-end fusion.
Chain and ring chromosome configurations were detected in a small percentage of the lymphocytes of a patient suffering from Thiberge-Weissenbach syndrome. Precise recognition of the chromosomes involved in the rearrangements did not indicate a systematic order of end-to-end fusions. A relationship between these configurations and the chromosome arrangement in the interphase nucleus is possible.
D002114:Calcinosis / Q000235:genetics*; D002869:Chromosome Aberrations; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008540:Meiosis; D008938:Mitosis; D012595:Scleroderma, Systemic / Q000235:genetics*; D013577:Syndrome; D013684:Telangiectasis / Q000235:genetics*