The effect of methallibure (I.C.I. 33,828) on the steriodogenesis in the ovary and testis of a fresh water teleost, Cyprinus carpio.
Methallibure treatment of mature Cyprinus carpio causes a marked reduction in the steroidogenesis, as indicated by the fall in 3beta-HSD activity in the gonads. Significance of these results is discussed.
D015096:3-Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D000818:Animals; D002347:Carps / Q000378:metabolism*; D003530:Cyprinidae / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005260:Female; D008297:Male; D008693:Methallibure / Q000494:pharmacology*; D010053:Ovary / Q000187:drug effects* / Q000201:enzymology; D013737:Testis / Q000187:drug effects* / Q000201:enzymology; D013890:Thiourea / Q000031:analogs & derivatives*; D013997:Time Factors
D015096:3-Hydroxysteroid Dehydrogenases; D013890:Thiourea; D008693:Methallibure