Change in taste preference related to aging of taste cells in rat.
Following the suppression of renewal of rat taste cells by vinblastine sulphate, the preference for sucrose decreased markedly while the aversion to quinine did not change. The results suggest that the sensitivity of taste cells to sucrose decreases with their aging, but the sensitivity to quinine increases.
D000375:Aging; D000818:Animals; D011803:Quinine / Q000494:pharmacology; D051381:Rats; D013395:Sucrose / Q000494:pharmacology; D013649:Taste; D013650:Taste Buds / Q000187:drug effects*; D014747:Vinblastine / Q000494:pharmacology
D013395:Sucrose; D014747:Vinblastine; D011803:Quinine