Extreme hyponatremia in patients with myelomatosis: an effect of cationic paraproteins.
Three patients with IgG myelomatosis and extreme hyponatremia are described. By isoelectric focusing of the M-component it is demonstrated that the subnormal sodium value is most likely explained by a cationic effect of the myeloma globulin.
D000368:Aged; D001859:Bone Neoplasms / Q000150:complications*; D002412:Cations; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000209:etiology*; D007075:Immunoglobulin M / Q000032:analysis; D007525:Isoelectric Focusing; D008297:Male; D009101:Multiple Myeloma / Q000150:complications* / Q000276:immunology
D002412:Cations; D007075:Immunoglobulin M