Renography in the foetal and newborn lamb.
Hippuran renography indicates kidney function as reflected in a substance handled mainly by the tubules. The working conditions of the kidneys undergo a fundamental change at birth with the cessation of placenta circulation, and these organs become responsible for waste elimination. 131I-hippuran renography was performed on foetal and newborn lambs using a gamma camera and a computer. The intervals of the maximum- and half-time renal activity were determined. These decreased by a half from mean foetal value of Tm=7 mi and T12=19 min in 1 to 1.5 days and reached the full-grown level in 2 to 5 weeks. No sudden change occurred as a result of the first breath.
D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D007465:Iodohippuric Acid; D007684:Kidney Tubules / Q000000981:diagnostic imaging / Q000196:embryology / Q000502:physiology*; D011859:Radiography; D011866:Radioisotope Renography / Q000295:instrumentation / Q000379:methods*; D012756:Sheep / Q000502:physiology*; D001743:Urinary Bladder / Q000502:physiology
D007465:Iodohippuric Acid