title: Lordosis induction in the rat by prostaglandin E2 systemically or intracranially in the absence of ovarian hormones.
abstract: Within 20 minutes of an intraperitoneal injection, PGE2 induced lordosis responding to manual stimulation in 6 of 9 rats that were ovariectomized-hysterectomized and hormonally untreated. Similarly, intracranial application of PGE2, through guide cannulae that were chronically-implanted in the basal hypothalamus, induced lordosis responding to manual stimulation within 10 minutes in ovariectomized, hormonally-untreated rats.
mesh_terms: D000818:Animals; D005260:Female; D007031:Hypothalamus / Q000187:drug effects*; D007274:Injections, Intraperitoneal; D010053:Ovary / Q000502:physiology*; D011187:Posture; D011458:Prostaglandins E / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D012726:Sexual Behavior, Animal / Q000187:drug effects*
chemical_list: D011458:Prostaglandins E