Properdin factor b-polymorphism in the population of Hessen, Germany.
The polymorphism of properdin factor B (Bf, C3 proactivator) in a population sample from Hessen, Germany has been investigated by agarose gel electrophoresis and immunofixation. In 522 unrelated individuals seven different phenotypes were observed and the following allele frequencies calculated: BfS = 0.7998, BfF = 0.1772, BfS0.7 = 0.0163 and BfF1 = 0.0077. Investigations of 100 families with 198 children and 30 mother-child combinations support the assumed autosomal codominant way of inheritance.
D000328:Adult; D002648:Child; D011415:Complement Factor B / Q000097:blood / Q000235:genetics*; D004792:Enzyme Precursors / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D005799:Genes, Dominant; D005828:Genetics, Population; D005860:Germany, West; D006801:Humans; D011110:Polymorphism, Genetic
D004792:Enzyme Precursors; D011415:Complement Factor B