The role of polyamines in the regulation of AMP deaminase isozymes.
The differential effects of polyamines on the activity of AMP deaminase isozyme A (from rat muscle) and isozyme B (from rat liver) are reported. Polyamines activate isozyme B but inhibit isozyme A.
D000659:AMP Deaminase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000818:Animals; D004789:Enzyme Activation / Q000187:drug effects; D007527:Isoenzymes / Q000037:antagonists & inhibitors / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D009709:Nucleotide Deaminases / Q000378:metabolism*; D011073:Polyamines / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D014018:Tissue Distribution
D007527:Isoenzymes; D011073:Polyamines; D009709:Nucleotide Deaminases; D000659:AMP Deaminase