title: Infusion at constant rate in vivo.
abstract: Infusion can be maintained at a constant rate over an extended period of time in vivo by the use of an implanted diffusion chamber. Plasma 59Fe was maintained at a constant level for 10 days when infused from a s.c. implant. Injected isotope was cleared exponentially with a half-clearance time of about 8 h.
mesh_terms: D000818:Animals; D007263:Infusions, Parenteral / Q000379:methods*; D007501:Iron / Q000097:blood; D007700:Kinetics; D008297:Male; D051381:Rats
chemical_list: D007501:Iron