[A case of Peutz-Jeghers syndrome combined with bilateral breast cancer, an adenocarcinoma of the cervix and ovarian genital cord neoplasms with annular tubules].
The clinico-pathological findings are presented in a case of Peutz-Jeghers syndrome associated with a bilateral mammary invasive ductal carcinoma, a well-differentiated mucinous adenocarcinoma of the cervix and microscopic, bilateral ovarian sex cord tumors with annular tubules. The sex cord tumor with annular tubules was described in 1970 by SCULLY, who recognized its striking association with the Peutz-Jeghers syndrome. Two cases of adenocarcinoma of the cervix and another case of uterine adenocarcinoma of unspecified localization associated with Peutz-Jeghers syndrome were found in the literature. It is possible that women with Peutz-Jeghers syndrome run an increased risk of developing adenocarcinoma of the uterine cervix.
D000230:Adenocarcinoma / Q000150:complications*; D001859:Bone Neoplasms / Q000209:etiology; D001943:Breast Neoplasms / Q000150:complications*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007417:Intestinal Polyps / Q000150:complications; D008408:Mastectomy; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010051:Ovarian Neoplasms / Q000150:complications*; D010580:Peutz-Jeghers Syndrome / Q000150:complications* / Q000235:genetics; D002583:Uterine Cervical Neoplasms / Q000150:complications*
Un cas de syndrome de Peutz-Jeghers associé à un carcinome mammaire bilatéral, à un adénocarcinome du col utérin et à des tumeurs des cordons sexuels à tubules annelés bilatérales dans les ovaires.