[Pharmacologic analysis of the biphasic postsynaptic potentials of an identified neuron of the mollusk Planorbarius corneus].
Identified neuron in the left pedal ganglion of the mollusc P. corneus responds by biphasic postsynaptic potential (BPSP) to nerve stimulation. The depolarizing phase of both the BPSP and the response to acetylcholine is abolished by tubocurarine, whereas the hypopolarizing phase is blocked by tetramethylammonium. The results obtained suggest that BPSP is due to activation of two kinds of cholinoreceptors in the neuronal membrane.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D005724:Ganglia / Q000166:cytology*; D008564:Membrane Potentials / Q000187:drug effects; D008974:Mollusca; D009474:Neurons / Q000187:drug effects; D013570:Synaptic Membranes / Q000187:drug effects; D013757:Tetraethylammonium Compounds / Q000494:pharmacology*; D014403:Tubocurarine / Q000494:pharmacology*
D013757:Tetraethylammonium Compounds; D000109:Acetylcholine; D014403:Tubocurarine
Farmakologicheskiĭ analiz dvukhfaznykh postsinapticheskikh potentsialov identifitsirovannogo neĭrona molliuska Planorbarius corneus.