Intracellular calcium: its movement during pentylenetetrazole-induced bursting activity.
The intracellular calcium concentration in the cytoplasm decreased and the calcium concentration near the cell membrane increased during bursting activity induced by pentylenetetrazole in snail neuron. Incubation in medium containing cobalt chloride or lanthanum chloride did not change this tendency, which suggests that this calcium distribution change is due to the stored calcium in the subcellular structure moving toward the cell membrane.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D004577:Electron Probe Microanalysis; D008274:Magnesium / Q000378:metabolism; D009474:Neurons / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D010433:Pentylenetetrazole / Q000494:pharmacology*; D010852:Picrotoxin / Q000494:pharmacology; D012908:Snails; D013331:Strychnine / Q000494:pharmacology
D002118:Calcium; D008274:Magnesium; D010433:Pentylenetetrazole; D010852:Picrotoxin; D013331:Strychnine