title: Comparisons of alum-precipitated and unprecipitated aqueous ragweed pollen extracts in the treatment of hay fever.
abstract: In 1969 and 1970, groups of patients with ragweed hay fever never before treated were started on preseasonal course of immunization with an alum precipitate of aqueous ragweed extract. A comparison between these two groups of patients and a similar group of patients treated with unprecipitated aqueous extract in 1968 shows that treatment with alum precipitate was safely initiated with fever injections even though a higher dose was administered. The larger cumulative dose appeared to give better IgG antibody responses and greater relief of symptoms. A repeat preseasonal course the next year again required fewer injections of the alum-precipitated extract than a repeat course of aqueous extract.
mesh_terms: D000917:Antibody Formation; D006801:Humans; D007167:Immunotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D011058:Pollen; D006255:Rhinitis, Allergic, Seasonal / Q000628:therapy*; D012882:Skin Tests
chemical_list: D010936:Plant Extracts