Physiological basis of anisometropic amblyopia.
In the visual cortex of kittens that have received their only visual experience while wearing a high-power lens before one eye, most neurons are dominated by input from the normal eye. Moreover, contrast sensitivity and resolving power are lower for stimulation through the originally defocused eye, mimicking psychophysical results from human anisometropic amblyopes.
D000550:Amblyopia / Q000503:physiopathology*; D000818:Animals; D001931:Brain Mapping; D002415:Cats; D004195:Disease Models, Animal; D009949:Orientation / Q000502:physiology; D012030:Refractive Errors / Q000503:physiopathology*; D014793:Visual Cortex / Q000503:physiopathology*; D014795:Visual Pathways / Q000503:physiopathology