title: Naja haje (Egyptian cobra) venom. Purification, some properties and the amino acid sequences of four toxins (CM-7, CM-8, CM-9, and CM-10b).
abstract: Four toxins (CM-7, CM-8, CM-9 and CM-10b) were purified from Naja haje haje (Egyptian cobra) venom by gel filtration on Sephadex G-50 followed by ion-exchange chromatography on CM-cellulose. They each contain 60 amino acid residues and are cross-linked by four intrachain disulphide bridges. The complete primary structure of the four toxins have been elucidated. The toxicities, the immunochemical properties, the sequences and invariant amino acid residues opf toxins CM-7, CM-8, CM-9 and CM-10b resemble the corresponding properties of the cytotoxin group.
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D004220:Disulfides / Q000032:analysis; D004546:Elapid Venoms / Q000302:isolation & purification; D008970:Molecular Weight
chemical_list: D000596:Amino Acids; D004220:Disulfides; D004546:Elapid Venoms