title: Synthesis of anticholinergic agents: N-methyl-4-piperidinyl alpha-benzoyloxy-alpha-cyclopentylphenylacetate salts.
abstract: The synthesis of a new anticholinergic agent, N-methyl-4-piperidinyl alpha-benzoyloxy-alpha-cyclopentylphenylacetate, obtained by reacting N-methyl-4-piperidinyl alpha-cyclopentylmandelate with benzoyl chloride in the presence of methyllithium, is reported. This material may be useful as an antiperspirant.
mesh_terms: D000818:Animals; D006801:Humans; D007928:Lethal Dose 50; D051379:Mice; D010276:Parasympatholytics / Q000138:chemical synthesis* / Q000633:toxicity; D010648:Phenylacetates / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D011680:Pupil / Q000187:drug effects; D011817:Rabbits; D013546:Sweating / Q000187:drug effects*
chemical_list: D010276:Parasympatholytics; D010648:Phenylacetates