[Effect of electrostimulation of the supraoptic region of the hypothalamus on lipid metabolism and the development of atherosclerosis].
A three-week electrical stimulation of the hypothalamic supraoptic zone in rabbits which were on atherogenic diet for 3 to 8 weeks accelerated and intensified the development of hypercholesterolemia and lipidosis of the coronary arteries, as well as the metabolic changes in the myocardial tissue. The latter changes were expressed in the reduction of the tissue noradrenaline level, diminution of the creatine phosphate content, and an increase of inorganic phosphorus and lactic acid.
D000818:Animals; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D004036:Diet, Atherogenic; D004558:Electric Stimulation; D004734:Energy Metabolism; D007031:Hypothalamus / Q000502:physiology*; D008055:Lipids / Q000097:blood*; D008297:Male; D009206:Myocardium / Q000378:metabolism / Q000473:pathology; D011817:Rabbits; D013495:Supraoptic Nucleus / Q000502:physiology*; D014280:Triglycerides / Q000097:blood
D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol
Vliianie élektrostimuliatsii supraopticheskoĭ oblasti gipotalamusa na lipidnyĭ obmen i razvitie ateroskleroza.