Specific in vivo binding of d-LSD in rat brain.
A reproducible in vivo d-LSD binding method in rat brain is described, with high affinity (Kd of 5 pmoles/g wet wt), stereospecificity (d- vs. 1-LSD) and regional selectivity. It may be a useful adjunct to in vitro methods for measuring changes in turnover at the synaptic level related to the intact receptor.
D000818:Animals; D001667:Binding, Competitive; D001921:Brain / Q000378:metabolism*; D002531:Cerebellum / Q000378:metabolism; D003342:Corpus Striatum / Q000378:metabolism; D008238:Lysergic Acid Diethylamide / Q000378:metabolism*; D008297:Male; D051381:Rats; D013237:Stereoisomerism
D008238:Lysergic Acid Diethylamide