[Inhibin-like activity in human ovarian follicular fluid (author's transl)].
A steroid-free proteinaceous substance with inhibin-like activity has been extracted from human ovarian follicular fluid by alcohol precipitation. This substance was capable of inhibiting the ovarian weight increase of hCG-treated immature female rats and also of suppressing the post-castration rise of serum FSH levels in immature male rats. Follicular fluid from small follicls obtained from regularly cycling women was--on the basis of protein- found to be more active than cystic follicular fluid obtained from a premenopausal woman. The possible role of inhibin in the regulation of human ovarian cycle has been discussed.
D000818:Animals; D001826:Body Fluids / Q000502:physiology*; D006063:Chorionic Gonadotropin / Q000008:administration & dosage; D005260:Female; D005640:Follicle Stimulating Hormone / Q000502:physiology; D006801:Humans; D008593:Menopause; D009929:Organ Size / Q000187:drug effects; D010053:Ovary / Q000502:physiology*; D051381:Rats
D006063:Chorionic Gonadotropin; D005640:Follicle Stimulating Hormone
Nachweis von Inhibin-Aktivität in der Follikelflüssigkeit menschlicher Ovarien.