[Somatostatin in the treatment of acute haemorrhage from a duodenal ulcer (author's transl)].
A massive haemorrhage from a duodenal ulcer verified on endoscopy in a 21 year-old patient was stopped by a 62--hour infusion of somatostatin at a dosage of 250 microgram/hour. Suppression of gastric secretion is probably more important than the reduction in splanchnic blood flow with regard to the mechanism of action of this drug. No side effects were observed.
D000293:Adolescent; D000328:Adult; D004381:Duodenal Ulcer / Q000150:complications*; D005750:Gastric Juice / Q000378:metabolism; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D010438:Peptic Ulcer Hemorrhage / Q000188:drug therapy*; D013004:Somatostatin / Q000008:administration & dosage / Q000627:therapeutic use*
D013004:Somatostatin
Somatostatin in der Behandlung der akuten Ulkusblutung.