title: [Evaluation of the bone marrow granulocyte reserve in patients with Hodgkin's disease during antiblastic polychemo- and radiation therapy].
abstract: The ethiocholanolone test was used to evaluate the granulocyte reserve in 22 patients with Hodgkin's disease before and during polychemical antiblastic and radiation therapy. Under basal conditions, the reserve was normal and its behavior was fairly constantly related to histological type. Stress is laid on the inadequacy of the simple leukocyte count as a guide to the planning of treatment by comparison with the more accurate picture offered by the granulocyte reserve.
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001853:Bone Marrow / Q000473:pathology*; D004359:Drug Therapy, Combination; D005043:Etiocholanolone; D005260:Female; D006098:Granulocytes; D006689:Hodgkin Disease / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D006801:Humans; D007958:Leukocyte Count; D007962:Leukocytes; D008212:Lymphocyte Depletion; D008297:Male; D008875:Middle Aged
chemical_list: D000970:Antineoplastic Agents; D005043:Etiocholanolone
vernacular_title: Valutazione della riserva granulocitaria midollare in pazienti con morbo di Hodgkin in corso di terapia antiblastica polichemioterapica e radiante.