title: Methadone dose and human sexual behavior.
abstract: Among 31 male and 17 female former addicts in methadone maintenance or drug-free treatment, the frequency of sexual behaviors was determined by questionnaires administered at least weekly over several weeks. Daily methadone dose (mg/kg) correlated significantly with frequency of genital contacts (r = -.54) and organs (-.43) among females, and with frequency of ejaculation (-.31) among males. Although open and nonblind, the study suggests that higher doses of methadone may suppress human sexual behavior.
mesh_terms: D000328:Adult; D004305:Dose-Response Relationship, Drug; D004542:Ejaculation / Q000187:drug effects; D007172:Erectile Dysfunction / Q000139:chemically induced; D005260:Female; D006556:Heroin Dependence / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D008691:Methadone / Q000008:administration & dosage* / Q000627:therapeutic use; D009948:Orgasm / Q000187:drug effects; D012737:Sex Factors; D012725:Sexual Behavior / Q000187:drug effects*
chemical_list: D008691:Methadone