Annulate lamellae in erythroblasts in the mice splenic colonies.
Lethally irradiated mice received a transfusion of normal bone marrow cells from the same strain mice. The transfused colony-forming cells (stem cells) were settled in the spleen of the recipient and proliferated in it into erythroblast colonies. Some of these mice were given chloramphenicol or thiamphenicol for 7 days after marrow cell transfusion. Annulate lamellae were frequently observed exclusively in the erythroblasts of the mice received a injection of thiamphenicol.
D000818:Animals; D002701:Chloramphenicol / Q000494:pharmacology; D004900:Erythroblasts / Q000187:drug effects / Q000648:ultrastructure*; D004912:Erythrocytes / Q000648:ultrastructure*; D051379:Mice; D008810:Mice, Inbred C57BL; D013154:Spleen / Q000648:ultrastructure*; D013839:Thiamphenicol / Q000494:pharmacology
D002701:Chloramphenicol; D013839:Thiamphenicol