X-ray microanalysis of isolated perfused rat hearts.
X-ray microanalysis was carried out on sections from isolated hearts perfused with a modified Krebs-Henseleit solution with or without isoproterenol. Changes in P, Ca and Zn concentrations could be detected after isoproterenol and some correlation with hemodynamic and morphological parameters was observed. Ratios between P/Ca in myonuclei and the ratios of interstitial cell to myofiber nucleus calcium were related directly to the state of the heart.
D000818:Animals; D002118:Calcium / Q000032:analysis; D004577:Electron Probe Microanalysis; D007545:Isoproterenol / Q000494:pharmacology; D008722:Methods; D008832:Microchemistry; D009206:Myocardium / Q000032:analysis*; D010477:Perfusion; D010758:Phosphorus / Q000032:analysis; D051381:Rats; D015032:Zinc / Q000032:analysis
D010758:Phosphorus; D015032:Zinc; D007545:Isoproterenol; D002118:Calcium