[Effect of various methods of administration of live poliovirus vaccine on the immunoglobulin levels in the blood serum and mouth mucosa secretion in children].
Oral vaccination with live trivalent poliomyelitis in the liquid form in drops exerts a considerable influence on the IgA content in oral cavity secretes. After immunization with same vaccine in capsules no significant changes in IgA levels could be observed in oral cavity secretes for a 18-week observation period. A considerable increase in IgA level in oral secretes in children vaccinated with vaccine in capsules was observed after a 4th administration of the vaccine given orally in drops. Inrrespective of the method of vaccine administrations in the blood serum there was a considerable increase in the levels of immunoglobulins of all classes in the course of vaccination.
D002214:Capsules; D004304:Dosage Forms; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007223:Infant; D009061:Mouth Mucosa / Q000276:immunology* / Q000378:metabolism; D011055:Poliovirus Vaccine, Oral / Q000008:administration & dosage*
D002214:Capsules; D004304:Dosage Forms; D007070:Immunoglobulin A; D011055:Poliovirus Vaccine, Oral
Vliianie raznykh metodov applikatsii zhivoĭ poliomielitnoĭ vaktsiny na dinamiku urovneĭ immunoglobulinov v syvorotke krovi i sekretakh polosti rta u detei.