Plasma prostaglandin concentrations in allergic bronchial asthma.
Prostaglandin (PG) E plasma levels, measured by radioimmunoassay using anti-PGB1 antibody, were higher in asthmatic patients than in normal subjects. PGF levels measured with anti-PGF2alpha antibody, were not significantly different between normals and asthmatics. Plasma PGE/F ratios were elevated in the asthmatic patients. The results fail to support the hypothesis of decreased PGE or increased PGF production as an etiological factor in asthma.
D000293:Adolescent; D001249:Asthma / Q000097:blood* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D011458:Prostaglandins E / Q000097:blood*; D011460:Prostaglandins F / Q000097:blood*
D011458:Prostaglandins E; D011460:Prostaglandins F