Congenital diaphragmatic hernia: hypoplastic lung and pulmonary vasoconstriction.
The abnormal pulmonary vasculature of the infant with congenital diaphragmatic hernia combined with a single expanded lung creates persistent pulmonary hypertension. Survival depends on the ability of the myocardium to withstand this increased work load until the second lung expands and pulmonary hypertension ceases.
D002245:Carbon Dioxide / Q000097:blood; D002319:Cardiovascular System / Q000503:physiopathology; D006548:Hernia, Diaphragmatic / Q000150:complications; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology; D007231:Infant, Newborn; D008168:Lung / Q000002:abnormalities* / Q000098:blood supply; D008170:Lung Compliance; D010100:Oxygen / Q000097:blood; D014692:Ventilation-Perfusion Ratio
D002245:Carbon Dioxide; D010100:Oxygen