[Insulin activity of blood serum of rabbits immunized with tick-borne encephalitis- and western-equine-encephalomyelitis viruses].
Administration of brain suspension of intact albino mice during the 1st, 3rd and 7th days after a single, double and prolonged (5-cycle) immunization of rabbits produced no significant changes in the functional condition of the insular apparatus. A single use in the capacity of an antigen of the brain tissue containing the tick-borne encephalitis or western horse encephalomyelitis viruses also led to no marked shifts in the blood serum insulin activity. In reimmunization with the virus-containing material the value analysed decreased on the 7th day in comparison with the 1st and the 3rd days after the antigenic stimulation. A suppression of the hormonal function of the insular apparatus of the pancreas during the 1st and the 7th days of study was noted after the hyperimmunization with the virus-containing brain suspensions.
D000818:Animals; D000956:Antigens, Viral; D004667:Encephalitis Virus, Western Equine / Q000276:immunology*; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology*; D007117:Immunization, Secondary; D007328:Insulin / Q000097:blood* / Q000172:deficiency; D007329:Insulin Antagonists; D008297:Male; D011817:Rabbits; D013997:Time Factors; D014765:Viral Vaccines / Q000008:administration & dosage*
D000956:Antigens, Viral; D007328:Insulin; D007329:Insulin Antagonists; D014765:Viral Vaccines
Insulinnaia aktivnost' syvorotki krovi krolikov, immunizirovannykh virusami kleshchevogo entsefalita i zapadnogo entsefalomielita loshadeĭ.