Clinical comparison of cardiac blood pool visualization with technetium-99m red blood cells labeled in vivo and with technetium-99m human serum albumin.
Technetium-99m red blood cells (Tc-RBC) labeled by an in vivo technique were compared with two preparations of Tc-99m human serum albumin (HSA) for cardiac blood-pool imaging. Relative distribution of the tracers was analyzed on end-diastolic frames of gated blood-pool studies and on whole-body (head to mid-thigh) anterior pinhole images. The Tc-RBC demonstrated greater relative percentage localization in the cardiac blood pool, higher target-to-background ratios in the left ventricle, and less liver concentration. For cardiac blood-pool imaging, Tc-RBC labeled by the in vivo approach appears to be superior to the two Tc-HSA preparations studied.
D002306:Cardiac Volume; D004912:Erythrocytes; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D007553:Isotope Labeling; D009200:Myocardial Contraction; D011877:Radionuclide Imaging; D012709:Serum Albumin; D013667:Technetium
D012709:Serum Albumin; D013667:Technetium