Primitive neuroectodermal tumors of the central nervous system in children.
A series of 18 primitive neuroectodermal tumors in children (15 cerebral and three spinal) is reported. These are highly malignant neoplasms, both histologically and clinically. They are rapidly growing tumors, with a brief duration of symptoms and a rapidly progressive course. Forty percent of the patients were alive at 6 months, only 10% at 1 year, and all patients had died within 2 years following diagnosis.
D001932:Brain Neoplasms / Q000473:pathology* / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008527:Medulloblastoma / Q000473:pathology; D009447:Neuroblastoma / Q000473:pathology; D010871:Pinealoma / Q000473:pathology; D013120:Spinal Cord Neoplasms / Q000473:pathology* / Q000628:therapy