Salicylate-induced hypoglycemia and ketoacidosis in a nondiabetic adult.
A 78-year-old nondiabetic woman was admitted to the hospital with salicylate-induced hypoglycemia. Ketosis was present with a moderate metabolic acidosis and primary respiratory alkalosis. The patient's mental status improved immediately following intravenous administration of glucose. The case illustrates salicylate's hypoglycemic activity, and that the metabolic acidosis may have exacerbated symptoms of cerebral glucopenia.
D000138:Acidosis / Q000139:chemically induced*; D000368:Aged; D000472:Alkalosis, Respiratory / Q000139:chemically induced; D001241:Aspirin / Q000009:adverse effects; D005260:Female; D005947:Glucose / Q000008:administration & dosage; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced* / Q000188:drug therapy; D007263:Infusions, Parenteral; D007662:Ketosis / Q000139:chemically induced; D012459:Salicylates / Q000009:adverse effects*
D012459:Salicylates; D005947:Glucose; D001241:Aspirin