[Electron microscopic study of the products from dissolving unstabilized fibrin with complex heparin compounds].
Effects of some heparin complex compounds (heparin-urea, adrenaline-heparin, fibrinogen-heparin complexes and secondary complex adrenalin-heparin-fibrinogen) on factor XIIIa unstabilized fibrin were studied using electron microscopy. Fibrillar network of unstabilized fibrin destroys with the formation of globular molecular particles similar to fibrinogen molecule or fibrin monomer ultrastructure. A mechanism of fibrinolytic action of all the complexes mentioned is probably the same, since under dissolving of unstabilized fibrin, structures are found, which are similar to those forming under dissolving of unstabilized fibrin with urea.
D055598:Chemical Phenomena; D002621:Chemistry; D004837:Epinephrine; D005337:Fibrin; D005340:Fibrinogen; D005342:Fibrinolysis; D006493:Heparin; D008854:Microscopy, Electron; D012996:Solutions; D014508:Urea
D012996:Solutions; D014508:Urea; D005337:Fibrin; D005340:Fibrinogen; D006493:Heparin; D004837:Epinephrine
Elektronno-mikroskopicheskoe issledovanie produktov restvoreniia nestabilizirovannogo fibrina kompleksynmi soedineniiami geparina.