[Effect of the central cholinolytic cyclosil on several functional characteristics of rat liver mitochondria].
The effectiveness of macroergic compounds formation was found to increase in the mitochondria of the rat liver incubated in the presence of cyclosil (0.04 mg/ml). The rate of O2 consumption was unchanged. A tendency to increase the K+ transport into mitochondria in the presence of cyclosil was noted. The data obtained testify to an increase of the mitochondrial energization in the presence of cyclosil.
D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D003517:Cyclopentanes / Q000494:pharmacology; D005260:Female; D008297:Male; D008566:Membranes / Q000378:metabolism; D008930:Mitochondria, Liver / Q000187:drug effects* / Q000378:metabolism; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D010101:Oxygen Consumption / Q000187:drug effects; D010276:Parasympatholytics / Q000494:pharmacology; D010627:Phenethylamines / Q000494:pharmacology*; D011188:Potassium / Q000378:metabolism*; D051381:Rats
D003517:Cyclopentanes; D010276:Parasympatholytics; D010627:Phenethylamines; C016331:cyclosil; D011188:Potassium
Vliianie tsentral'nogo kholinolitika tsiklozina na nekotorye funktsional'nye kharakteristiki mitokhondriĭ pecheni krys.