Growth and cytopathic effect of rubella virus in primary and progeny guinea pig kidney cells.
A culture system useful for the demonstration of cytopathology of rubella virus in guinea pig kidney cells is described. Not only were cytopathic rubella infections dependent on cell type (primary lung cells were not responsive), but infection early in primary passage was also necessary. Secondary-passage kidney cells were unresponsive. The cytopathic phenomenon did not appear to depend on any special medium or on inhibition of the normal interferon response.
D000818:Animals; D002478:Cells, Cultured; D003470:Culture Media; D003588:Cytopathogenic Effect, Viral; D006168:Guinea Pigs; D007668:Kidney; D012412:Rubella virus / Q000254:growth & development*; D014776:Virus Cultivation / Q000379:methods
D003470:Culture Media