title: Perfluorooctyl bromide concentration in plasma and tissues of beagle dogs.
abstract: Plasma levels were determined frequently after single doses of perfluorooctyl bromide were administered to beagle dogs at doses of either 30.8 g/kg po or 3.9 g/kg intratracheally. The apparent first-order half-life during the terminal elimination phase was about 1 day after oral medication and about 7 days after intratracheal administration. Analysis of tissues revealed the highest concentrations of the compound in abdominal fat of dogs autopsied 4 weeks later.
mesh_terms: D000818:Animals; D004285:Dogs; D005260:Female; D005466:Fluorocarbons / Q000032:analysis* / Q000097:blood; D006842:Hydrocarbons, Brominated; D008297:Male; D014018:Tissue Distribution
chemical_list: D005466:Fluorocarbons; D006842:Hydrocarbons, Brominated; C003072:perflubron