[Comparative estimate of methods used in the examination of the sensitizing properties of chemical compounds].
The studies carried out aim at comparing and determining the usefulness of two methods most frequently used to evaluate the sensitizing properties of chemical compounds. In the studies, compounds of known sensitizing properties have been used: potassium dichromate and 2,4-dinitrochlorobenzene. Comparison of the percentage of sensitized guinea--pigs, intensity of sensitizing reaction and the time at which the reaction is being kept up, indicates a greater usefulness of Magnusson and Kligman's method for routine evaluation of sensitizing properties of chemical compounds.
D000818:Animals; D002840:Chromates / Q000276:immunology*; D004137:Dinitrochlorobenzene / Q000276:immunology*; D005260:Female; D006168:Guinea Pigs; D008297:Male; D009578:Nitrobenzenes / Q000276:immunology*; D009787:Occupational Medicine; D011192:Potassium Dichromate / Q000276:immunology*
D002840:Chromates; D004137:Dinitrochlorobenzene; D009578:Nitrobenzenes; D011192:Potassium Dichromate
Porównawcza ocena metod stosowanych do badania właściwości uczulajacych zwiazków chemicznych.