title: Loss of cell-population-density-dependent incorporation of fucose into the lipid fraction of cultured human tumour cells.
abstract: The incorporation of radioactively labelled fucose into the lipid fraction of cultured normal human cells and several human tumour-cell lines was examined as a function of the cell population density. Normal cells exhibited a density-dependent pattern of incorporation, whereas in tumour cells the radioactivity incorporated was independent of the cell population density. An exception was found among the tumour cells, which suggests a possible correlation between the loss of this marker and the ability to produce tumours.
mesh_terms: D002452:Cell Count; D002478:Cells, Cultured; D005643:Fucose / Q000378:metabolism*; D006801:Humans; D050356:Lipid Metabolism; D009369:Neoplasms / Q000378:metabolism*
chemical_list: D005643:Fucose