The effect of photochemotherapy on epidermal-glycogen and on capillaries in psoriatic skin.
This study was undertaken to assess the amount of glycogen present in psoriasis vulgaris (PV), psoriasis erythrodermica (PE) and psoriasis pustulosa generalisata (PPG) lesions before and after photochemotherapy (PUVA). There were more deposits of glycogen in PPG than in PE and PV. With PUVA treatment, glycogen almost completely disappeared in PV and PE, but traces were still observed in PPG. After treatment, the epidermal layers returned to their normal structure but there was no significant improvement in the dilated and tortuous capillaries in the upper corium.
D002196:Capillaries / Q000378:metabolism* / Q000473:pathology; D004817:Epidermis / Q000378:metabolism* / Q000473:pathology; D005069:Evaluation Studies as Topic; D005363:Ficusin / Q000627:therapeutic use; D006003:Glycogen / Q000378:metabolism*; D006801:Humans; D010778:Photochemotherapy; D011565:Psoriasis / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D012867:Skin / Q000098:blood supply*
D006003:Glycogen; D005363:Ficusin