title: A simplified test of epinephrine responsiveness.
abstract: Forty-three ocular hypertensive and 33 ocular normotensive subjects received two doses of topical 1% epinephrine hydrochloride in one eye. The epinephrine was administered twice, ie, at time "zero" (8 AM) and 12 hours later (at 8 PM). The mean intraocular pressure responses at four hours and at 24 hours (12 hours after the last dose of epinephrine) were significantly correlated, r = 0.59 (P less than .001). This suggested that the simpler four-hour test was an equally accurate measure of the ocular responsiveness to topical epinephrine.
mesh_terms: D004837:Epinephrine / Q000494:pharmacology; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D011379:Prognosis; D013997:Time Factors
chemical_list: D004837:Epinephrine