title: Amoebic liver abscess in Wessex--a retrospective survey of 24 cases.
abstract: The clinical features and response to treatment of 24 patients with amoebic liver abscess in Wessex are presented. Two patients died before adequate treatment could be instituted, but 6 of the remaining 22 patients (27%) did not respond to single courses of conventional anti-amoebic therapy. Possible reasons for this high failure rate are discussed. It is concluded that although Metronidazole is a highly effective anti-amoebicide, there remains a place for other drugs such as Emetine. The importance of early diagnosis of Amoebic Liver Abscess is emphasised.
mesh_terms: D000328:Adult; D004640:Emetine / Q000627:therapeutic use; D004739:England; D005260:Female; D006801:Humans; D008101:Liver Abscess, Amebic / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D008795:Metronidazole; D004640:Emetine