Dipivalyl epinephrine: a new pro-drug in the treatment of glaucoma.
The dansyl chloride technique in conjunction with thin layer chromatography and autoradiography has shown that dipivalyl epinephrine is a pro-drug in the human eye. Dipivalyl epinephrine appears to be a more effective epinephrine compound, in that it penetrates the cornea approximately 17 times greater than epinephrine.
D001082:Aqueous Humor / Q000032:analysis; D001345:Autoradiography; D002250:Carbon Radioisotopes; D002855:Chromatography, Thin Layer; D003315:Cornea / Q000378:metabolism; D004837:Epinephrine / Q000378:metabolism; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans
D002250:Carbon Radioisotopes; D004837:Epinephrine