Insemination of husband's semen with and without the addition of caffeine.
Four hundred cervicovaginal artificial inseminations using husband's semen were carried out for a variety of clinical indications. Before insemination, to one-half of the samples caffeine was added to a final concentration of 6 mM. Although the motility of the spermatozoa was enhanced in each case, no pregnancies were achieved. Of the four pregnancies in the series, only one could be attributed to artificial insemination.
D002110:Caffeine / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007315:Insemination, Artificial; D007317:Insemination, Artificial, Homologous; D008297:Male; D011247:Pregnancy; D012661:Semen / Q000187:drug effects*; D013081:Sperm Motility / Q000187:drug effects
D002110:Caffeine