title: [Increase with age of the frequency of spontaneous karyotype disorders in mice].
abstract: 328 oocytes from 874 studied were found suitable for counting chromosomes. 263 oocytes (80.18%) had a normal chromosome number, while aneuploidy was observed in 18.3% of oocytes (61). Among then 46 (14.02%) were with hypoploidy and 14 oocytes (4.26%) were hyperploid with 21 chromosomes and over. Structural chromosome aberrations were found in 24 oocytes (7.31%).
mesh_terms: D000367:Age Factors; D000818:Animals; D002869:Chromosome Aberrations / Q000453:epidemiology*; D025063:Chromosome Disorders; D005260:Female; D007621:Karyotyping; D008540:Meiosis; D008677:Metaphase; D051379:Mice; D009865:Oocytes / Q000648:ultrastructure; D009866:Oogenesis
vernacular_title: Uvelichenie chastoty spontannykh narusheniĭ kariotipa s vozrastom mysheĭ.