[Identification and properties of proteins characteristic of the Shvets rat leukosis].
Blood proteins were examined in rats with the Shvets experimental leukosis positively reacting in the sedimentation test for leukosis. Application of monospecific antisera against main classes of immunoglobulins shows that this protein belongs to immunoglobulins of the class G. The sedimentation constant and molecular weight of the protein under study are determined. It is shown that immunoglobulin G of rats with leukosis activates glycolysis and inhibits respiration. The data obtained give reasons to assume not complete identity but, in any case, similarity of physicochemical properties of proteins appearing in animal and human blood channel with malignant growth.
D000818:Animals; D006019:Glycolysis / Q000187:drug effects; D007074:Immunoglobulin G / Q000032:analysis* / Q000494:pharmacology; D007942:Leukemia, Experimental / Q000097:blood*; D008970:Molecular Weight; D009363:Neoplasm Proteins / Q000097:blood*; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats; D014461:Ultracentrifugation
D007074:Immunoglobulin G; D009363:Neoplasm Proteins
Identifikatsiia i svoistva belka, kharakternogo dlia leikova Shvetsa krys.