Prostaglandin F2alpha distribution in pregnant rats.
Studies on the placental transfer and distribution of 3H-PGF2alpha in rats on day 14 of gestation revealed that the isotope and/or its metabolites readily crossed the placenta. Notable levels of radioactivity were present in the embryos as well as in the placentas. The highest concentration of radioactivity was detected in the amniotic fluid. Maternal liver, kidney, and gut also showed significant uptake of the isotope.
D000653:Amniotic Fluid / Q000378:metabolism; D000818:Animals; D004622:Embryo, Mammalian / Q000378:metabolism; D005260:Female; D007413:Intestinal Mucosa / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D011460:Prostaglandins F / Q000008:administration & dosage / Q000378:metabolism*; D051381:Rats; D014316:Tritium
D011460:Prostaglandins F; D014316:Tritium