Proteinase inhibitors of bovine nasal cartilage.
Extracts from bovine nasal cartilage with 1 M-guanidinium chloride were fractionated by ultrafiltration. Gel chromatography of the low-molecular-weight material resolved three distinct fractions with inhibitory activity against (a) collagenases (22000 mol.wt.), (b) thiol proteinases cathepsin B and papain (13000 mol.wt.), and (c) trypsin and other serine proteinases (7000 mol.wt.).
D000818:Animals; D002356:Cartilage / Q000032:analysis*; D002417:Cattle; D002850:Chromatography, Gel; D004791:Enzyme Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology; D009666:Nose; D011480:Protease Inhibitors
D004791:Enzyme Inhibitors; D011480:Protease Inhibitors