[Perinatal influences on blood coagulation in healthy newborn infants with special reference to vitamin K administration].
In a prospective study the daily milk intake and weight gain were recorded in 169 healthy newborn infants during the first week of life. Factor II, V and VII activities were determined on the fourth day using a capillary blood method with hematocrit correction factor. Late onset of feeding showed a major influence on factor II and VII activities. In full-term newborns factor II was correlated to the birth weight. Mode of delivery, color of amniotic fluid, umbilical cord round the neck, Apgar score and postnatal vitamin K prophylaxis showed no significant influence. In infants with abnormal cardiotocographic findings higher levels of factor II were determined. This can be explained by stress-induced liver maturation.
D000653:Amniotic Fluid; D001034:Apgar Score; D001778:Blood Coagulation Disorders / Q000517:prevention & control*; D001779:Blood Coagulation Factors / Q000032:analysis*; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000517:prevention & control*; D011247:Pregnancy; D014812:Vitamin K / Q000008:administration & dosage*
D001779:Blood Coagulation Factors; D014812:Vitamin K
Perinatale Einflüsse auf die Blutgerinnung von gesunden Neugeborenen unter besonderer Berücksichtigung der Ernährung und der Vitamin K-Prophylaxe.