[Incorporation of 14-c-1-glycine into tissue proteins under the influence of insulin and its derivatives].
Effect of parenterally injected insulin and its composite sulpho-A- and B-chains on the rate of protein synthesis by the organs of the rat was investigated. It has been shown that insulin accelerates the incorporation of I-C14-glycine into proteins of the liver, kidneys, pancreas, spleen, sceletal muscules, thyroid gland, thymus and adrenal glands but does not influence this process in the cardiac muscle and diaphragm. A- and B-chains also activated protein metabolism in some organs, but despite some specificity of their action its extent was more limited as compared to that of insulin.
D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D005998:Glycine / Q000378:metabolism*; D007328:Insulin / Q000031:analogs & derivatives / Q000494:pharmacology*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000378:metabolism; D009928:Organ Specificity; D010179:Pancreas / Q000378:metabolism; D014176:Protein Biosynthesis; D051381:Rats; D013154:Spleen / Q000378:metabolism; D013950:Thymus Gland / Q000378:metabolism; D013961:Thyroid Gland / Q000378:metabolism
D007328:Insulin; D005998:Glycine
Vkliuchenie glitsina-1-14C v tkanevye belki pod vliianiem insulina i ego proizvodstva.