Effect of prednisolone on motor end-plate fine structure: a morphometric study in hamsters.
The fine structure of quadriceps motor end-plates in hamsters was analyzed quantitatively one, two, four, seven, and thirty-two weeks following intraperitoneal injections of prednisolone. Except for transient increases in postsynaptic length and membrane profile concentration after prednisolone administration at dosages of 4 mgper kilogram of body weight for one week and 2 mg per kilogram for four weeks, mean values for various measurable profiles in the presynaptic and postsynaptic regions showed no significant differences between control and treated animals.
D000818:Animals; D006224:Cricetinae; D008297:Male; D008647:Mesocricetus; D009045:Motor Endplate / Q000187:drug effects* / Q000648:ultrastructure; D009469:Neuromuscular Junction / Q000187:drug effects*; D011239:Prednisolone / Q000494:pharmacology*; D013569:Synapses / Q000187:drug effects / Q000648:ultrastructure
D011239:Prednisolone