title: [Bone isoenzyme fraction of alkaline phosphatase in patients undergoing prolonged hemodialysis treatment].
abstract: The values of serum concentration of alkaline phosphatase and of bone isoenzyme fraction, determined by thermal inactivation of serum were followed up in 42 patients with chronic renal insufficieny, treated with hemodialysis for a long time. The authors found that the elevation of those valuse correlates with the degree of the manifested changes in the bone skeleton. Attention is paid to the fact that the determination of bone and liver isoenzymes of alkaline phosphatase could help the earlier diagnosis of bone changes and infectious hepatitis, both being frequent complications in patients treated with hemodialysis.
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood*; D001847:Bone Diseases / Q000175:diagnosis; D001842:Bone and Bones / Q000201:enzymology*; D004796:Clinical Enzyme Tests; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D007676:Kidney Failure, Chronic / Q000201:enzymology; D006435:Renal Dialysis / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D007527:Isoenzymes; D000469:Alkaline Phosphatase
vernacular_title: Kostna izoenzimna fraktsiia na alkalnata fosfataza pri patsienti s produlzhitelno khemodializno lechenie.