title: Management of pancreatic trauma.
abstract: Since 1950, 300 patients sustaining pancreatic injuries have been managed. Three-fourths of the injuries were due to penetrating trauma with a 20% mortality and one-fourth due to blunt trauma resulting in an 18% mortality. The pancreatic injury was responsible for death in only 3% of patients. Early onset of shock resulted in 38% mortality whereas only 4% of normotensive patients died. No patient died of an isolated pancreatic injury. Sepsis was the second most common cause of death following hemorrhage. Preoperative serum amylase was elevated more frequently following blunt trauma than penetrating trauma, but did not correlate with injury. There has been a tendency toward more frequent use of distal pancreatectomy for simple penetrating injuries without obvious ductal violation which increases operative time, blood loss and possible intra-abdominal abscess since resection usually requires splenectomy. Patients considered for an 80% distal resection are better managed with a Roux-en-Y limb to the distal pancreas since three patients developed diabetes following an 80% or greater resection. A conservative approach consisting of Penrose and sump drainage is adequate for most injuries.
mesh_terms: D000007:Abdominal Injuries / Q000401:mortality; D000293:Adolescent; D000328:Adult; D000368:Aged; D000681:Amylases / Q000097:blood; D001424:Bacterial Infections; D002648:Child; D002675:Child, Preschool; D003920:Diabetes Mellitus / Q000209:etiology; D004322:Drainage / Q000379:methods; D004386:Duodenum / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D010179:Pancreas / Q000293:injuries* / Q000601:surgery; D010180:Pancreatectomy / Q000379:methods; D010181:Pancreatic Cyst / Q000209:etiology; D010185:Pancreatic Fistula / Q000209:etiology; D010195:Pancreatitis / Q000209:etiology; D012774:Shock, Traumatic / Q000401:mortality; D013530:Surgical Wound Infection; D014949:Wounds, Nonpenetrating / Q000601:surgery; D014950:Wounds, Penetrating / Q000601:surgery
chemical_list: D000681:Amylases