title: Taste preference test for oral liquid theophylline preparations.
abstract: Taste preferences among three oral liquid theophylline preparations were evaluated in 54 males. The products tested, and their theophylline concentrations, were Elixophyllin Pediatric Suspension (Cooper Laboratories, Inc.), 100 mg/5 ml; Somophyllin Oral Liquid (Fisons Corporation), 90 mg/5 ml; and Theophyl-225 Elixir (Knoll Pharmaceutical Company), 37.5 mg/5 ml. Generally-recommended procedures for taste tests were followed. The results indicated a taste preference for Theophyl-225 Elixir, followed by Elixophyllin Pediatric Suspension, followed by Somophyllin Oral Liquid. The results were statistically significant (p = 0.05). Product concentration and formulation were suggested to be major factors in determining taste preference.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D006801:Humans; D008297:Male; D008722:Methods; D012996:Solutions; D013535:Suspensions; D013649:Taste; D013806:Theophylline
chemical_list: D012996:Solutions; D013535:Suspensions; D013806:Theophylline