title: Two transsexuals with 47-XYY karyotype.
abstract: Previous reports of sexual orientation and gender identity in subjects with XYY karyotype are reviewed. Two patients seeking a change of sex operation and found to have an XYY karyotype are described. It is argued that an XYY karyotype may predispose to a disturbed gender identity and possibly to the development of the transsexual syndrome.
mesh_terms: D000328:Adult; D005783:Gender Identity; D006801:Humans; D008297:Male; D012729:Sex Chromosome Aberrations / Q000523:psychology*; D014189:Transsexualism / Q000235:genetics*; D014997:XYY Karyotype / Q000523:psychology*