Triamcinolone-induced mammary activation in virgin mice.
Intact ICR mice receiving Triamcinolone showed extensive proliferation within the mammary gland. Galactophores and ducts were enlarged. In contrast with the non-treated animals, those treated with Triamcinolone had an evident lobuloalveolar system. Triamcinolone failed to activate the glands of oophorectomized animals. It is thus evident that systemic administration of Triamcinolone to young virgin mice causes mammary stimulation and that this effect only occurs in the presence of the ovary.
D000818:Animals; D002369:Castration; D005260:Female; D008321:Mammary Glands, Animal / Q000033:anatomy & histology / Q000187:drug effects*; D051379:Mice; D008813:Mice, Inbred ICR; D010053:Ovary / Q000502:physiology; D014221:Triamcinolone / Q000494:pharmacology*
D014221:Triamcinolone