title: [Analysis of the daily human requirements for thiamine in the newly arrived population of Polar regions].
abstract: The erythrocytes transketolase activity and the TDP-effect were determined in persons residing in the regions beyond the polar circle and these demonstrated a moderate thiamine deficiency. The daily thiamine intake with food in the examined did not exceed 1.5 mg, the thiamine-diphosphate of the epoenzyme amounting to 90 per cent. Following introduction of various pharmacological preparations of vitamin B1 for a space of 2 weeks a somewhat greater transketolase activity and a diminution of the TDP-effect were observed. Administration of cocarboxylase and vitamin B1 with Mg and gelatin more favourable changes were obtained. Some macro- and micro-elements were found to exercise a positive effect on the thiamine assimilation by the tissues. The results obtained indicate that the daily thiamine requirement (allowance) of man in the North does not surpass 1.5-2.0 mg. To control hypovitaminoses in the North it is more effective to use natural vitamin-carriers rather than pharmacological preparations of vitamin B1.
mesh_terms: D000293:Adolescent; D000328:Adult; D002940:Circadian Rhythm; D003081:Cold Climate; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate; D008669:Metallurgy; D009747:Nutritional Physiological Phenomena; D009751:Nutritional Requirements; D013831:Thiamine / Q000008:administration & dosage / Q000378:metabolism*; D013832:Thiamine Deficiency / Q000517:prevention & control; D013835:Thiamine Pyrophosphate / Q000097:blood; D013997:Time Factors; D014174:Transketolase / Q000097:blood; D014586:USSR
chemical_list: D014174:Transketolase; D013835:Thiamine Pyrophosphate; D013831:Thiamine
vernacular_title: Analiz sutochnoĭ potrebnosti cheloveka v tiamine u prishlogo naseleniia Zapoliar'ia.