Ultrasonic enhancement of cancer radiotherapy.
Ultrasound treatment (1.5 W/cm2, 1.9 MHz, C.W.) for 15 minutes either before or after x irradiation reduced the TCD50 of sarcoma-180 by approximately 40% while similar ultrasound treatment for up to 30 minutes did not reduce the TCD50 of the C3HBA mammary adenocarcinoma. Water bath heating (44.5 degrees C for 15 minutes) after x irradiation reduced the TCD50 of both tumors. Ultrasound alone for up to 30 minutes had no effect on growth or cure rate of either tumor.
D000818:Animals; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000532:radiotherapy / Q000628:therapy; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000532:radiotherapy / Q000628:therapy*; D011836:Radiation Tolerance; D011879:Radiotherapy Dosage; D012510:Sarcoma 180 / Q000532:radiotherapy / Q000628:therapy; D014184:Transplantation, Homologous; D014464:Ultrasonic Therapy; D014964:X-Ray Therapy