The pseudouridine contents of the ribosomal ribonucleic acids of three vertebrate species. Numerical correspondence between pseudouridine residues and 2'-O-methyl groups is not always conserved.
The pseudouridine contents of the rRNA species of HeLa cells, mouse L-cells and Xenopus laevis cultured kidney cells were examined. Pseudouridine, like 2'-O-methylation, was found to occur relatively frequently in each of the high-molecular-weight rRNA species. However, the numerical data do not support the idea that there is a general one-to-one relationship between pseudoridine residues and 2'-O-methyl groups in vertebrate rRNA.
D000818:Animals; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D002854:Chromatography, Paper; D006367:HeLa Cells / Q000032:analysis; D006801:Humans; D007739:L Cells / Q000032:analysis; D008745:Methylation; D051379:Mice; D011560:Pseudouridine / Q000032:analysis*; D012335:RNA, Ribosomal / Q000032:analysis*; D014529:Uridine / Q000031:analogs & derivatives*; D014981:Xenopus
D012335:RNA, Ribosomal; D011560:Pseudouridine; D014529:Uridine