Dosage of hemoglobin A1c by isoelectrofocusing.
A new Hb A1c routine dosage method is proposed, using thin-layer isoelectrofocusing. The mean level in normal adults is 4.66% (sigma = 1.05). In diabetic (treated) patients, the distribution of Hb A1c levels is a non-Gaussian one, with extreme values of 3 to 13% and a maximum frequency peak at 5.5%.
D000328:Adult; D003920:Diabetes Mellitus / Q000097:blood; D004591:Electrophoresis, Polyacrylamide Gel; D006441:Hemoglobin A / Q000032:analysis*; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D007525:Isoelectric Focusing; D008722:Methods
D006454:Hemoglobins; D006441:Hemoglobin A