title: The toxicity and efficiency of arecoline hydrobromide in the Tasmanian hydatid control program.
abstract: Results on the efficiency and toxicity of arecoline hydrobromide during the first 11 years of the hydatid limitation program in Tasmania are presented. A satisfactory mucous purge was obtained from about 80% of dogs when arecoline was used at 3.25 mg/kg and from about 75% when the dose rate was reduced to 1.62 mg/kg of body weight. Arecoline is considered to have a low efficiency in detecting tapeworm infection in individual dogs, but is valuable as a diagnostic aid in groups of dogs. Toxicity was seen as acute cardiac collapse in about 5 dogs per 1000 dosed. Deaths followed in 1 dog in about 9,500.
mesh_terms: D000818:Animals; D001115:Arecoline / Q000009:adverse effects; D001315:Australia; D002400:Cathartics; D004283:Dog Diseases / Q000175:diagnosis* / Q000517:prevention & control; D004285:Dogs; D004443:Echinococcosis / Q000175:diagnosis / Q000517:prevention & control / Q000662:veterinary*; D013622:Taeniasis / Q000175:diagnosis / Q000662:veterinary*; D013997:Time Factors
chemical_list: D002400:Cathartics; D001115:Arecoline