Time factor in PHA responsiveness of human blood lymphocytes after in vitro irradiation.
Human blood lymphocytes were irradiated in vitro prior to or following PHA-stimulation. Radiation dose-response profiles indicate that PHA-pretreatment of cells has no protective effect. PHA-reactivity of the cells decreases with increase of the time interval between irradiation and subsequent PHA stimulation.
D002478:Cells, Cultured; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008213:Lymphocyte Activation / Q000528:radiation effects*; D008214:Lymphocytes / Q000528:radiation effects*; D010835:Phytohemagglutinins / Q000494:pharmacology*; D013997:Time Factors
D010835:Phytohemagglutinins