[Distribution of atomic density in protein globules].
The distribution of atomic density in the elastase and subtilysin globulas was modeled on the basis of their x-ray atomic coordinates and was consequently investigated through comparison with the normal Poisson distribution, using the chi2-test. The results from the above procedure are discussed in connection with the concept of kinetic constraints on the globula folding process as well as with the enzyme-machine hypothesis. It is shown that the minimum average dimensions of atomic irregularities in the protein globula are about 200 A3.
D010196:Pancreatic Elastase; D011487:Protein Conformation; D013381:Subtilisins; D014961:X-Ray Diffraction
D013381:Subtilisins; D010196:Pancreatic Elastase
O raspredelenii atomnoĭ plotnosti v belkovykh globulakh.