In vitro activity of rosamicin and erythromycin against a group of nonfermenting gram-negative bacilli.
The in vitro inhibitory activity of rosamicin and erythromycin against 283 strains of nonfermenting, gram-negative bacilli was determined by using a broth dilution procedure. Rosamicin demonstrated greater activity than erythromycin against most strains tested. A number of species demonstrated significantly lower minimum inhibitory concentrations to rosamicin and would fall within the therapeutic range of the drug based on current pharmacological data.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004917:Erythromycin / Q000494:pharmacology*; D005417:Flavobacterium / Q000187:drug effects*; D006088:Gram-Negative Aerobic Bacteria / Q000187:drug effects*; D007933:Leucomycins / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents; D007933:Leucomycins; D004917:Erythromycin