Interference between two immune responses. II.--Conferrability by the serum of the influences exerted by a response to horse RBC on the subsequent response to sheep RBC in the mouse.
Serum taken from mice responding to HoRBC and given to syngeneic mice influences the kinetics of a subsequent anti-SRBC response. The serum taken at the 36th of the anti-HoRBC response exerts after transfer an accelerating effect on the anti-SRBC response while this of the 7th day has an inhibitory effect. Both effects are especially demonstrative on mice irradiated and restored with spleen cells from a single donor because of the low variation coefficient of their anti-SRBC response.
D000818:Animals; D000917:Antibody Formation / Q000528:radiation effects; D003429:Cross Reactions; D004912:Erythrocytes / Q000276:immunology* / Q000528:radiation effects; D006736:Horses / Q000276:immunology; D007116:Immunization, Passive; D051379:Mice; D008807:Mice, Inbred BALB C; D008815:Mice, Inbred Strains; D012756:Sheep / Q000276:immunology; D013154:Spleen / Q000276:immunology; D013997:Time Factors; D014965:X-Rays