[103Ru for tumor scanning--a comparative study on tissue distributions of 103Ru-chloride and 103Ru-citrate in tumor-bearing animals (author's transl)].
Biological distribution of 103Ru in mice bearing Ehlrich's solid tumor and rats bearing AH-130 solid tumor were studied with two compounds of 103Ru, the chloride and citrate. The radioactivity of 103Ru-chloride showed slower excretion and higher tumor concentration than that of citrate. The tumor-to-muscle ratios of chloride were always higher, but the tumor-to-blood ratios were always lower than those of citrate. No significant difference was founds between 103Ru-chloride and citrate as tumor scanning agents.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000000981:diagnostic imaging / Q000378:metabolism*; D002712:Chlorides / Q000378:metabolism; D002951:Citrates / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D008297:Male; D051379:Mice; D009132:Muscles / Q000378:metabolism; D011868:Radioisotopes / Q000378:metabolism*; D011877:Radionuclide Imaging; D012428:Ruthenium / Q000378:metabolism*
D002712:Chlorides; D002951:Citrates; D011868:Radioisotopes; D012428:Ruthenium