title: Synthesis, metabolism, and antitumor activity of deuterated analogues of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea.
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000378:metabolism / Q000627:therapeutic use; D002851:Chromatography, High Pressure Liquid; D003903:Deuterium; D066298:In Vitro Techniques; D007553:Isotope Labeling; D008130:Lomustine / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000378:metabolism / Q000627:therapeutic use; D008223:Lymphoma / Q000188:drug therapy; D013058:Mass Spectrometry; D008862:Microsomes, Liver / Q000378:metabolism; D009374:Neoplasms, Experimental / Q000188:drug therapy; D009607:Nitrosourea Compounds / Q000138:chemical synthesis*; D051381:Rats; D013237:Stereoisomerism
chemical_list: D000970:Antineoplastic Agents; D009607:Nitrosourea Compounds; D008130:Lomustine; D003903:Deuterium