Vitiligo, chronic thrombocytopenia, and autoimmune hemolytic anemia.
A 12-year-old boy with vitiligo, chronic thrombocytopenia, and a Coombs's positive autoimmune hemolytic anemia was treated with oral psoralens and exposure to ultraviolet light. An acute hemolytic crisis developed and he died. The association of autoimmune hemolytic anemia and vitilligo should be looked for in other cases. Until more information is available, patients with vitiligo and thrombocytopenia should not be treated with psoralens and exposure to ultraviolet light.
D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications*; D002648:Child; D002908:Chronic Disease; D006801:Humans; D008297:Male; D013921:Thrombocytopenia / Q000150:complications*; D014820:Vitiligo / Q000150:complications*