title: Bilateral iliacus haematoma with femoral nerve palsy complicating anticoagulant therapy.
abstract: A patient is reported who sustained bilaterial iliacus haematoma with femoral nerve palsy during treatment with constant intravenous infustion of heparin for deep venous thrombosis. She was promptly treated with operative decompression and recovered completely from the palsy. Daily examinations of the blood revealed that the plasma heparin concentration, activated partial thromboplastin time, APTT, and thrombin time all were above the therapeutic range at the time when the bleeding started, and before the initial symptoms occurred. Early operative decompression is considered to be the ideal treatment in patients who develop this complication during anticoagulant therapy.
mesh_terms: D005260:Female; D005267:Femoral Nerve; D006406:Hematoma / Q000139:chemically induced* / Q000150:complications / Q000601:surgery; D006493:Heparin / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007263:Infusions, Parenteral; D008875:Middle Aged; D009135:Muscular Diseases / Q000139:chemically induced* / Q000150:complications / Q000601:surgery; D009408:Nerve Compression Syndromes / Q000209:etiology* / Q000601:surgery; D010243:Paralysis / Q000209:etiology*; D012187:Retroperitoneal Space
chemical_list: D006493:Heparin