[Hemoglobin XXIII: note on the sequence of the delta-chains of human hemoglobin (author's transl)].
The minor component of the human adult hemoglobin Hb A2 (alpha2/delta2) was isolated. The peptide chains were separated by counter current distribution, the delta-chains digested with trypsin and all hydrolysis splitting products separated and quantitatively characterized. With the film technique the different peptides were sequenced with hydrophilic phenylisothiocyanates I and IV or by the propyne programme. The complete sequence of the delta-chains is given and compared with the sequence reported in former investigations, in which the delta-chain sequence was only partly elucidated. Having completely sequenced the delta-chains of the human hemoglobin, we found the 10 previously reported exchanges and no additional exchanges with respect to the beta-chains.
D000328:Adult; D000595:Amino Acid Sequence; D006441:Hemoglobin A / Q000302:isolation & purification*; D006454:Hemoglobins / Q000302:isolation & purification*; D006801:Humans
D006454:Hemoglobins; D006441:Hemoglobin A
Hämoglobine, XXIII. Notiz zur Sequenz der delta-Ketten der menschlichen Hämoglobine (Hb A2 = alpha2/delta2).