title: Strongyloides ratti infections in rats. II. Effects of cortisone treatment.
abstract: Cortisone (5 mg daily subcutaneously) suppressed both primary and secondary immune explusion of Strongyloides ratti, and reduced the intestinal mast cell response, but did not induce hyperinfection in rats. Cortisone-treated animals expelled primary worm burdens without complication about 2 wk after steroid treatment. A model for gastrointestinal hypersensitivity syndromes in discussed.
mesh_terms: D000818:Animals; D003348:Cortisone / Q000494:pharmacology*; D005260:Female; D007165:Immunosuppression Therapy; D007421:Intestine, Small / Q000469:parasitology / Q000473:pathology; D008297:Male; D008407:Mast Cells / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D013322:Strongyloidiasis / Q000276:immunology* / Q000469:parasitology / Q000473:pathology
chemical_list: D003348:Cortisone