[Granulocyte function in septicemia of the newborn (author's transl)].
The ingestion- and Nitro Blue Tetrazolium-(NBT)-reduction-capacity of neutrophil leukocytes in three newborn infants with lethal septicemia was studied using a modified NBT-test. In comparison to 25 controls in healthy newborns (umbilical vein-blood) the results indicate a failure in the functioning of leukocytes. Besides other disturbances the impaired ingestion- and NBT-reduction-capacity of the neutrophil granulocytes during an infection probably leads to septicemia.
D005260:Female; D005312:Fetal Blood; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood*; D008297:Male; D009504:Neutrophils / Q000378:metabolism / Q000473:pathology*; D009580:Nitroblue Tetrazolium / Q000378:metabolism; D018805:Sepsis / Q000097:blood*
D009580:Nitroblue Tetrazolium
Störung der Ingestions- und NBT-Reduktionskapazität neutrophiler Granulocyten während letal verlaufender Sepsis im Neugeborenenalter. Vorläufige Mitteilung.