title: Structural elements in adenovirus cores. Studies by means of freeze-fracturing and ultrathin sectioning.
abstract: Rod-like elements have been observed in adenovirions after freeze-fracturing of purified, semi-purified and intra-cellular adenovirus type 5. Their rod-like shape was clearly demonstrated by means of stereomicrographs. Ultrathin sections prepared in parallel with the freeze-fracture replicas revealed linear structures such as ribbons, rings or rods in up to 30 per cent of the semi-purified or intracellular virus particles. These observations indicate that the main 'structural element' in the adenovirus interior is a linear structure either fragmented into 5 to 6 'rods' or folded 5 to 6 times to fit into the inner space of the virion.
mesh_terms: D000260:Adenoviruses, Human / Q000648:ultrastructure*; D002213:Capsid / Q000648:ultrastructure; D002460:Cell Line; D005614:Freeze Fracturing; D005629:Frozen Sections; D008961:Models, Structural; D014764:Viral Proteins; D014771:Virion / Q000648:ultrastructure
chemical_list: D014764:Viral Proteins