[Incontinentia pigmenti. Chromosomal study of a family (author's transl)].
After lymphocyte culture, chromosomic study has been performed on a woman and her daughter suffering from incontinentia pigmenti as well as on the two healthy brothers. This study has shown a high rate of chromosomic breakage in the four subjects, which confirms the facts mentioned in several previous reports. As far as genetic advice is concerned, the discovery of an excess of chromosomic breakage in a healthy subject who is a close relative of a patient, should prompt caution.
D000015:Abnormalities, Multiple / Q000235:genetics*; D000328:Adult; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010859:Pigmentation Disorders / Q000235:genetics*
Incontinentia pigmenti. Etude chromosomique d'une famille.