title: [Distribution of atomic density in protein globules].
abstract: The distribution of atomic density in the elastase and subtilysin globulas was modeled on the basis of their x-ray atomic coordinates and was consequently investigated through comparison with the normal Poisson distribution, using the chi2-test. The results from the above procedure are discussed in connection with the concept of kinetic constraints on the globula folding process as well as with the enzyme-machine hypothesis. It is shown that the minimum average dimensions of atomic irregularities in the protein globula are about 200 A3.
mesh_terms: D010196:Pancreatic Elastase; D011487:Protein Conformation; D013381:Subtilisins; D014961:X-Ray Diffraction
chemical_list: D013381:Subtilisins; D010196:Pancreatic Elastase
vernacular_title: O raspredelenii atomnoĭ plotnosti v belkovykh globulakh.