title: Children absorb tris-BP flame retardant from sleepwear: urine contains the mutagenic metabolite, 2,3-dibromopropanol.
abstract: The flame retardant, tris(2,3-dibromopropyl)phosphate (tris-BP), which is a mutagen and causes cancer and sterility in animals is absorbed from fabric by people. 2,3-Dibromopropanol, a metboloite of tris-BP and a mutagen itself, has been found in the urine samples of ten children who were wearing or who had worn tris-BP-treated sleepwear. Eight of these children were wearing well-washed sleepwear and the possibility of absorption of tris-BP from well-washed sleepwear discussed. 2,3-Dibromopropanol was not found in the urines of one child and one adult who had never worn tris-BP-treated garments.
mesh_terms: D000433:1-Propanol / Q000652:urine; D002648:Child; D002849:Chromatography, Gas; D003020:Clothing; D005260:Female; D005411:Flame Retardants / Q000378:metabolism*; D006801:Humans; D006842:Hydrocarbons, Brominated / Q000378:metabolism; D013058:Mass Spectrometry / Q000379:methods; D009153:Mutagens / Q000378:metabolism*; D010755:Organophosphates / Q000378:metabolism*; D020005:Propanols; D012869:Skin Absorption
chemical_list: D005411:Flame Retardants; D006842:Hydrocarbons, Brominated; D009153:Mutagens; D010755:Organophosphates; D020005:Propanols; C012085:tris(2,3-dibromopropyl)phosphate; D000433:1-Propanol; C016369:2,3-dibromopropanol