The bovine alveolar macrophage. II. In vitro studies with Pasteurella haemolytica.
Bovine alveolar macrophages were cultured in vitro and challenged with suspensions of live and dead bacteria. These cells showed severe cytotoxic morphological changes and a low rate of phagocytosis after exposure to live Pasteurella haemolytica type I was readily phagocytosed and produced only mild cytotoxic changes.
D000818:Animals; D002417:Cattle; D002478:Cells, Cultured; D003470:Culture Media; D003603:Cytotoxins / Q000096:biosynthesis; D066298:In Vitro Techniques; D008264:Macrophages / Q000502:physiology*; D010325:Pasteurella / Q000378:metabolism; D010587:Phagocytosis; D011650:Pulmonary Alveoli / Q000166:cytology*
D003470:Culture Media; D003603:Cytotoxins