The epinephrine effect in renal angiography revisited.
The effect of various doses of epinephrine on the renal vessels was studied angiographically in 15 kidneys including three renal tumours. Commonly used doses (10--25 microgram) are often too high as demonstrated in this study. Our findings indicate that the optimal dose for pharmacoangiography of renal masses should be 2--5 microgram of epinephrine. The time interval between drug administration and angiography should be less than 1 min and optimally in the range of 10--30s.
D000328:Adult; D000368:Aged; D000792:Angiography; D004305:Dose-Response Relationship, Drug; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D006801:Humans; D007668:Kidney / Q000098:blood supply* / Q000187:drug effects; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D004837:Epinephrine