[Ultrastructural features of cerebral synapses in schizophrenic patients].
The paper is concerned with ultrastructural traits of synapses in the frontal lobe, supraoptical nucleus of the hypothalamus and caudal nucleus of the brain in 12 schizophrenic patients and 8 normals (the period of autopsy was 4 hours following death). The results demonstrated 2 types of changes: 1) slightly expressed changes (a decrease of the extent of active zone contacts, changed forms in the synaptical vesicles); 2) extremely expressed or degenerative changes in the synapses (an appearance of fibrillar structures, glycogene granules, degeneration of synaptical endings of a dark type).
D001921:Brain / Q000648:ultrastructure*; D002421:Caudate Nucleus / Q000648:ultrastructure; D005625:Frontal Lobe / Q000648:ultrastructure; D006801:Humans; D012559:Schizophrenia / Q000473:pathology*; D013495:Supraoptic Nucleus / Q000648:ultrastructure; D013569:Synapses / Q000648:ultrastructure*
Ul'trastrukturnye osobennosti sinapsov mozga bol'nykh shizofrenieĭ.