[Immunogenic properties of cholerogen-toxoid and killed corpuscular vaccine in acute experiments on guinea pigs].
A comparative assessment of the immunogenicity of cholerogen toxoid and of killed corpuscular cholera vaccine was given. Guinea pigs immunized with cholerogen toxoid acquired a greater resistance to the intrapulmonary infection with virulent cholera vibrio culture (immunity index--2.1.10(4)) than those immunized with killed corpuscular vaccine (immunity index--3.5.10(2)). Immunogenicity of cholerogen toxoid could be increased in its combined administration with killed corpuscular vaccine.
D000818:Animals; D002771:Cholera / Q000517:prevention & control*; D022121:Cholera Vaccines / Q000008:administration & dosage / Q000276:immunology; D004338:Drug Combinations; D006168:Guinea Pigs; D014121:Toxoids / Q000008:administration & dosage / Q000276:immunology; D014611:Vaccination
D022121:Cholera Vaccines; D004338:Drug Combinations; D014121:Toxoids
Immunogennye svoĭstva kholerogen-anatoksina i ubitoĭ korpuskuliarnoĭ vaktsiny v ostrykh opytakh na morskikh svinok.