[Haemodynamic data, blood gas measurements and coagulation disorders in acute respiratory failure of patients with chronic lung disease (author's transl)].
24 subjects with chronic obstructive pulmonary disease were investigated in the course of acute respiratory failure defined by hypoxaemia, hypercapnia and respiratory acidosis. Haemodynamic data of right heart catheterization and coagulation tests were particularly studied. 12 of these subjects had right heart failure defined by a rise of right ventricular end-diastolic pressure above 10 Torr. Coagulation tests brought evidence of consumption coagulopathy in 8 patients, 7 of whom had right heart failure. Data suggest a significant correlation between right heart failure and coagulation disorders in patients with acute exacerbation of chronic obstructive pulmonary disease. These disturbances, accompanied by reduction of pulmonary vascular area, could be in part related to the presence of microthrombi in pulmonary arterial vessels.
D000368:Aged; D001778:Blood Coagulation Disorders / Q000150:complications; D001794:Blood Pressure; D005260:Female; D006333:Heart Failure / Q000150:complications*; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000150:complications*; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D012131:Respiratory Insufficiency / Q000150:complications / Q000503:physiopathology*; D013927:Thrombosis / Q000150:complications
Données hémodynamiques, gazométriques et troubles de l'hémostase chez les insuffisants respiratoires chroniques en décompensation aiguüe.