The absolute configuration of urinary 2-hydroxybutyric acid in patients with ketosis and lactic acidosis.
The absolute configurations of urinary 2-hydroxybutyrate and 3-hydroxybutyrate were determined in patients with lactic acidemia and ketosis by capillary gas-liquid chromatography of their O-acetylated (--)-menthyl ester derivatives. 2-Hydroxybutyrate had the L-configuration, whereas 3-hydroxybutyrate was in the D-configuration.
D000138:Acidosis / Q000652:urine*; D002849:Chromatography, Gas / Q000379:methods; D006801:Humans; D006885:Hydroxybutyrates / Q000652:urine*; D007536:Isomerism; D007662:Ketosis / Q000652:urine*; D007773:Lactates / Q000097:blood / Q000652:urine*; D013058:Mass Spectrometry; D008968:Molecular Conformation; D013237:Stereoisomerism
D006885:Hydroxybutyrates; D007773:Lactates