Functional role of collateral flow in the ischaemic dog heart.
Studies were carried out in four different canine preparations to determine the effect of collateral flow on early changes induced by acute segmental ischaemia. The results of these experiments indicated that collateral flow provided a limited and variable amount of protection. When collateral flow was eliminated, myocardial cell injury was more severe and less variable.
D000818:Animals; D003097:Collateral Circulation; D003327:Coronary Disease / Q000473:pathology / Q000503:physiopathology*; D004285:Dogs; D004562:Electrocardiography; D008854:Microscopy, Electron; D009206:Myocardium / Q000648:ultrastructure