Scanning electron microscopic evaluation of the surfaces of artificial hearts.
This report summarizes the surface changes seen in artificial hearts implanted in calves for periods up to four months. Fabrication defects as well as degradation resulting from wear are identified. SEM evaluation of the blood contacting surface as well as the surface of the diaphragm associated with the drive mechanisms has revealed potential problems with current heart designs and methods of fabrication. Materials evaluation of implanted hearts is crucial for a clinically useful system to evolve.
D000818:Animals; D000925:Anticoagulants / Q000627:therapeutic use; D001672:Biocompatible Materials; D002417:Cattle; D006041:Goats; D006354:Heart, Artificial / Q000009:adverse effects; D008297:Male; D008855:Microscopy, Electron, Scanning; D011140:Polyurethanes; D012826:Silicone Elastomers; D013927:Thrombosis / Q000209:etiology / Q000517:prevention & control
D000925:Anticoagulants; D001672:Biocompatible Materials; D011140:Polyurethanes; D012826:Silicone Elastomers