title: Clinical application of 201Tl scintigraphy in patients with cold thyroid nodules.
abstract: 201Tl-chloride scintigraphy was performed in 45 patients with cold thyroid nodules. The 201Tl scintigram was positive in 17 of 18 thyroid patients with cancer (94.4%), 8 of 20 patients with an ademoma (40.0%), 1 of 2 adenomatous goiter patients (50.0%), and all of 5 cases of chronic thyroiditis (100.0%). When the cold nodule was demonstrated to be positive with 201Tl, the statistical chance of the lesion being a cellular one was 100.0% and a risk of its malignancy was 54.8%. On the other hand, the nodule with negative 201Tl concentration had a 14.3% chance of cellularity and a 7.1% risk of malignancy. Thus, 201Tl scintigraphy is of use in the differential diagnosis of the cold thyroid nodule.
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000000981:diagnostic imaging; D000236:Adenoma / Q000000981:diagnostic imaging; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000000981:diagnostic imaging; D003537:Cystadenoma / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D006044:Goiter, Nodular / Q000000981:diagnostic imaging*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013793:Thallium; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging*; D013966:Thyroiditis / Q000000981:diagnostic imaging
chemical_list: D011868:Radioisotopes; D013793:Thallium