Internal cesium alters sodium inactivation in Myxicola.
When Myxicola giant axons are internally dialyzed with Cs+ as the sole cation, the time-course of prepulse inactivation is selectively accelerated compared to its rate with K+ dialysis in the same axons. This decrease in tauph occurs without any change in the magnitude or time-course of INa during step depolarizations and results in tauph/taush ratios near unity over most of the potential range in Cs+ dialyzed axons.
D000818:Animals; D001369:Axons / Q000187:drug effects; D002586:Cesium / Q000494:pharmacology*; D003956:Dialysis; D008564:Membrane Potentials / Q000187:drug effects; D011077:Polychaeta / Q000187:drug effects* / Q000378:metabolism; D011188:Potassium / Q000494:pharmacology; D012964:Sodium / Q000037:antagonists & inhibitors* / Q000494:pharmacology
D002586:Cesium; D012964:Sodium; D011188:Potassium