[Properties of the nervous tissue cholinesterase and carboxylesterase in the locust, Locusta migratoria].
It was shown that locust cholinesterase splits various thiocholine esters with different rate. Hydrolysis of p-NPA is due to the effect of carboxylesterase. The latter differs from cholinesterase by a low sensitivity to eserine and cation-containing organophosphorus inhibitor methylsulfomethylate-O-ethyl-S-(beta-ethylmercaptoethyl) methylthiophosphonate, as well as by higher sensitivity to triorthocresylphosphate. The results obtained are discussed in relation to possible differences of the active surface of the enzymes studied.
D000085:Acetates / Q000378:metabolism; D000818:Animals; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism*; D002802:Cholinesterases / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation / Q000187:drug effects; D006110:Grasshoppers / Q000201:enzymology*; D006868:Hydrolysis; D009417:Nerve Tissue / Q000201:enzymology*; D009596:Nitrophenols / Q000378:metabolism; D013860:Thiocholine / Q000378:metabolism
D000085:Acetates; D009596:Nitrophenols; D013860:Thiocholine; D002265:Carboxylic Ester Hydrolases; D002802:Cholinesterases
Svoĭstva kholinésterazy i karboksilésterazy nervnoĭ tkani saranchi Locusta migratoria.