title: Lipid metabolism in laying hens. The relationship of plasma lipids and liver fatty acid synthetase activity to changes in liver composition.
abstract: Plasma and liver samples were taken from a random sample of caged commercial hybrid layer hens which had been in egg production for fifteen months. The concentration of plasma and liver lipids and the activity of liver fatty acid synthetase (FAS) were measured in laying hens with liver weight of 20 to 53 g. Liver total lipid, water, non-lipid, and cytosolic fractions, which are the four major liver components, increased linearly with respect to wet liver weight. FAS activity increased with all liver components. Accumulation of lipid in the liver did not inhibit FAS activity. Total cholesterol, free cholesterol, esterified cholesterol, triglycerides, and phosphorous were measured on each plasma sample. Multiple regression analysis showed that all plasma lipids, except cholesterol esters, were related cubically with increasing wet liver weight and cytosolic protein.
mesh_terms: D000818:Animals; D002645:Chickens / Q000378:metabolism* / Q000502:physiology; D002784:Cholesterol / Q000097:blood; D003600:Cytosol / Q000032:analysis; D064429:Fatty Acid Synthases / Q000378:metabolism*; D005260:Female; D008055:Lipids / Q000032:analysis / Q000097:blood*; D008099:Liver / Q000032:analysis* / Q000201:enzymology; D010058:Oviposition; D011506:Proteins / Q000032:analysis; D014280:Triglycerides / Q000097:blood
chemical_list: D008055:Lipids; D011506:Proteins; D014280:Triglycerides; D002784:Cholesterol; D064429:Fatty Acid Synthases