[Changes in rat liver lysosomes following stimulation of recovery processes in the damaged organ by triton WR-1339].
The effect of a single injection of lysosomotropic agent--Triton WR-1339 on the properties of the rat liver lysosomes and the course of pathological process during chronic toxic hepatitis were studied. Triton WR-1339 administration was followed by a more rapid restoration of the liver structure and function. A possible mechanism of the favourable effect of Triton WR-1339 is discussed.
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy*; D002466:Cell Nucleolus / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy*; D002908:Chronic Disease; D008099:Liver / Q000648:ultrastructure; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D051381:Rats; D012260:Ribonucleases / Q000378:metabolism; D013448:Sulfobromophthalein / Q000378:metabolism
D013448:Sulfobromophthalein; D011092:Polyethylene Glycols; D012260:Ribonucleases; D000135:Acid Phosphatase
Osobennosti izmeneniĭ lizosom pecheni krys pri stimuliatsii vosstanovitel'nykh protsessov tritonom WR-1339 v povrezhdennom organe.