Evaluation of the effect of p-chloroamphetamine on individual catecholaminergic nuclei in the rat brain.
Short and long term effects of p-chloroamphetamine (PCA) on levels of catecholamines (CA) in discrete CA cell body and axon terminal areas were investigated. The levels were unaffected, except for a transient fall in dopamine in the arcuate nucleus. These results do not support the suggestion that PCA is neurotoxic to CA cells.
D000662:Amphetamines / Q000494:pharmacology*; D000818:Animals; D001369:Axons / Q000378:metabolism; D001921:Brain / Q000166:cytology / Q000378:metabolism*; D002395:Catecholamines / Q000378:metabolism*; D008297:Male; D051381:Rats; D013997:Time Factors; D010133:p-Chloroamphetamine / Q000494:pharmacology*
D000662:Amphetamines; D002395:Catecholamines; D010133:p-Chloroamphetamine