title: Ellipticines as potent inhibitors of aryl hydrocarbon hydroxylase: their binding to microsomal cytochromes P450 and protective effect against benzo(a)pyrene mutagenicity.
mesh_terms: D000470:Alkaloids / Q000494:pharmacology*; D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases / Q000037:antagonists & inhibitors*; D001579:Benzopyrene Hydroxylase / Q000037:antagonists & inhibitors*; D001580:Benzopyrenes / Q000037:antagonists & inhibitors*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D004247:DNA / Q000378:metabolism; D004611:Ellipticines / Q000378:metabolism / Q000494:pharmacology*; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D009153:Mutagens / Q000037:antagonists & inhibitors*; D051381:Rats; D012475:Salmonella / Q000187:drug effects / Q000235:genetics
chemical_list: D000470:Alkaloids; D001580:Benzopyrenes; D004611:Ellipticines; D009153:Mutagens; D004247:DNA; D003577:Cytochrome P-450 Enzyme System; D001579:Benzopyrene Hydroxylase; D001189:Aryl Hydrocarbon Hydroxylases