The effect of oral magnesium chloride therapy on the QTc and QUc intervals of the electrocardiogram.
The effect of magnesium, given orally as enteric-coated magnesium chloride tablets, on the ECG of 25 randomly selected patients was investigated. Each patient, who served as his own control, was given 4--6 tablets, each containing 0,5 g MgCl26H2O, at night for periods varying from 6 weeks to 2 years. Findings included (i) a statistically significant decrease in OTc and QUc intervals; (ii) a progressive shortening of QTc and QUc intervals with continuing therapy; (iii) reversion to normal of ECG abnormalities, especially of ST segments and T waves.
D000284:Administration, Oral; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008274:Magnesium / Q000008:administration & dosage* / Q000494:pharmacology; D008297:Male; D009206:Myocardium / Q000378:metabolism
D008274:Magnesium