[Bacteriostatic and bactericidal action of bile acids and antibiotics on staphylococci].
It was found in vitro that desoxycholic, cholic, glycocholic and choleinic acids inhibited the growth and development of staphylococci. The staphylococci isolated from bile were more resistant to the bacteriostatic and bactericidal effect of bile acids than the microorganisms isolated from other sources not containing cholates. Under the effect of these substances the activity of some antibiotics especially those from the group of aminoglycosides markedly increased.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001646:Bile / Q000382:microbiology; D001647:Bile Acids and Salts / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004357:Drug Synergism; D006801:Humans; D013210:Staphylococcus / Q000187:drug effects*; D013492:Suppuration / Q000382:microbiology
D000900:Anti-Bacterial Agents; D001647:Bile Acids and Salts; D004338:Drug Combinations
Bakteriostaticheskoe i bakteritsidnoe deĭstvie zhelchnykh kislot i antibiotikov na stafilokokki.