title: Nerve grafting.
abstract: By avoiding tension and securing anatomical neurorrhaphy, regeneration of nerve is obtainable. When the gap exceeds a certain limit, the only way to avoid tension is the use of grafts. Experience in animal experiments and clinical practice has demonstrated that regenerating axons can cross 2 optimal suture lines much more easily than one sub-standard one. For bridging a gap autografts are used, because in autografts the fascicular pattern is preserved and its Swann cells survive. With the interfascicular technique the dissection of the nerve stumps proceeds from normal to abnormal tissues and the epineurium is resected. The coaptation must be exact so that the grafts cover the whole cross sectional area of the fascicle. All this can be achieved by the use of one 10--0 or 11--0 nylon suture. The clinical results show that in the median nerve 82%, in the ulnar 80% and in the radial nerve 92% of good functional results can be obtained. Also in brachial plexus injuries the interfascicular nerve grafting procedure opened new ways. Therefore interfascicular nerve grafting, using autografts in cases of nerve repair, where a gap may occur, currently is the method of choice.
mesh_terms: D000818:Animals; D001917:Brachial Plexus / Q000601:surgery; D006801:Humans; D008475:Median Nerve / Q000637:transplantation; D008722:Methods; D009416:Nerve Regeneration; D011826:Radial Nerve / Q000637:transplantation; D013127:Spinal Nerves / Q000637:transplantation*; D013497:Sural Nerve / Q000637:transplantation; D014182:Transplantation, Autologous; D014459:Ulnar Nerve / Q000637:transplantation