Ultrastructural changes in the lungs after chronic experimental intoxication with benzine and ethyline vapour.
In the group of rabbits chronically intoxicated with petrol vapour slight changes in the dust cells of lungs in the form of cytoplasmic vacuolisation and accumulation of collagen almost completely disappeared 3 months after intoxication. Changes in animals intoxicated with ethyline were much more severe. Besides the accumulation of collagen, appearance of elastin areas, cytolysosomes, changes in the nucleus, widening of ergastoplasm, swelling and cristolysis of mitochondria were observed. Three months after intoxication the decrease of previously observed changes was noted.
D000818:Animals; D005742:Gasoline / Q000633:toxicity*; D007855:Lead Poisoning / Q000473:pathology*; D008168:Lung / Q000187:drug effects / Q000473:pathology* / Q000648:ultrastructure; D008171:Lung Diseases / Q000139:chemically induced* / Q000473:pathology; D010578:Petroleum / Q000633:toxicity*; D011817:Rabbits
D005742:Gasoline; D010578:Petroleum