Low levels of serum calcium, phosphorus and plasma 25-hydroxy vitamin D in cirrhosis of the liver.
In a retrospective analysis of 78 patients with liver cirrhosis, we found low serum levels of calcium and phosphorus. The low calcium levels showed a better correlation with high activity of aspartate aminotransferase than with low levels of albumin. In addition, there was a relationship between low calcium and low phosphorus levels. Therefore, factors other than, and in addition to, hypoalbuminemia seem to be responsible for the low calcium and phosphorus levels in cirrhosis patients. Although low levels of serum 25-hydroxyvitamin D were found in 23 of our patients, there was no indication that hypovitaminosis D was causative factor in the hypocalcemia and hypophosphatemia.
D001219:Aspartate Aminotransferases / Q000097:blood; D002118:Calcium / Q000097:blood*; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood*; D006996:Hypocalcemia / Q000097:blood; D007008:Hypokalemia / Q000097:blood; D008103:Liver Cirrhosis / Q000097:blood* / Q000201:enzymology; D010758:Phosphorus / Q000097:blood*; D012709:Serum Albumin / Q000032:analysis; D014808:Vitamin D Deficiency / Q000097:blood
D006887:Hydroxycholecalciferols; D012709:Serum Albumin; D010758:Phosphorus; D001219:Aspartate Aminotransferases; D002118:Calcium