Visual evoked responses in multiple sclerosis: comparison of two methods for pattern reversal.
Visual evoked responses have been elicited by reversal of a black and white checkerboard pattern and also by a display of light-emitting diodes (LED) generating a reversal of a pattern of illuminated red circular areas. In a control group the LED display produced responses of lower amplitude and shorter latency compared to responses to checkerboard stimulation. In patients with a definite or probable diagnosis of multiple sclerosis the stimulators were equally effective in evoking pathological responses; in patients with a possible but less certain diagnosis abnormal responses were found in a higher percentage when the LED stimulus was used. Differences in stimulus field size and in stimulus colour are discussed as possible reasons for this result.
D000328:Adult; D003118:Color Perception; D005071:Evoked Potentials; D007839:Functional Laterality; D006801:Humans; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000503:physiopathology*; D009900:Optic Nerve / Q000503:physiopathology; D009902:Optic Neuritis / Q000175:diagnosis / Q000503:physiopathology*; D010364:Pattern Recognition, Visual; D010775:Photic Stimulation / Q000379:methods*; D011930:Reaction Time; D014787:Vision Tests