[Effectiveness of nerobol and enteral oxygen therapy in experimental liver dystrophy].
Experiments were conducted on 115 female albino rats; a study was made of the efficacy of nerobol and enteral oxygen therapy in acute dystrophy of the liver on the 7th and 14th days after the beginning of carbon tetrachloride administration. The use of nerobol, particularly in its combination with oxygen therapy, favoured gain in weight of the animals, improved their general condition, accelerated normalization of hepatic functions. Treatment promoted more rapid and complete restoration of the intensity of bile secretion, enhanced the synthesis of free bile acids, and also their conjugation with glycine and taurine. When combined with enteral oxygen therapy the efficacy of nerobol increased considerably.
D000208:Acute Disease; D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000150:complications; D056486:Chemical and Drug Induced Liver Injury / Q000628:therapy*; D004341:Drug Evaluation; D005260:Female; D006520:Hepatitis, Animal / Q000628:therapy*; D008696:Methandrostenolone / Q000627:therapeutic use*; D010100:Oxygen / Q000008:administration & dosage* / Q000627:therapeutic use; D051381:Rats; D013270:Stomach
D008696:Methandrostenolone; D010100:Oxygen
Effektivnost' nerobola i enteral'noĭ oksigenoterapii pri eksperimental'noĭ distrofii pecheni.