Studies on the crystalline form of phenytoin.
Two crystalline forms of phenytoin were isolated and characterized by X-ray diffraction, IR spectroscopy and differential thermal analysis. The dissolution behavior of the two forms was determined in water. The crystals of needle shape (form II) were found to exhibit slower dissolution rate than the other crystal form (form I).
D002626:Chemistry, Pharmaceutical; D003460:Crystallization; D010316:Particle Size; D010672:Phenytoin; D012995:Solubility; D013055:Spectrophotometry, Infrared; D014961:X-Ray Diffraction
D010672:Phenytoin