Anticholinergic drugs, buccal ulceration and mucosal potential difference.
Measurement of changes in buccal mucosal potential difference produced by contact with drug formulations may provide a means of predicting their mucosal toxicity and ulcerogenic activity.
D000328:Adult; D000368:Aged; D002610:Cheek; D004629:Emepronium / Q000009:adverse effects* / Q000494:pharmacology; D005260:Female; D006801:Humans; D008564:Membrane Potentials / Q000187:drug effects; D009059:Mouth Diseases / Q000139:chemically induced*; D009061:Mouth Mucosa / Q000187:drug effects / Q000503:physiopathology*; D011413:Propantheline / Q000009:adverse effects* / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds / Q000009:adverse effects*; D014456:Ulcer / Q000139:chemically induced
D000644:Quaternary Ammonium Compounds; D004629:Emepronium; D011413:Propantheline