Bencyclan: a new drug with unusual membrane stabilising properties in erythrocytes.
Bencyclan, a drug recently introduced to treat peripheral circulatory disease, has been shown to stabilise human erythrocytes in hypotonic saline. Two peaks of maximum stabilisation are present: at 10(-5)--10(-4) M and at 10(-3) M drug concentration.
D001537:Bencyclane / Q000494:pharmacology*; D003508:Cycloheptanes / Q000494:pharmacology*; D004910:Erythrocyte Membrane / Q000187:drug effects*; D004912:Erythrocytes / Q000187:drug effects*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D007038:Hypotonic Solutions; D066298:In Vitro Techniques; D009996:Osmotic Fragility / Q000187:drug effects
D003508:Cycloheptanes; D007038:Hypotonic Solutions; D001537:Bencyclane