Posterior urethral stenosis in newborn with renal nonfunction syndrome.
A newborn male infant presented with the "renal nonfunction syndrome" and subsequently was found at autopsy to have congenital stenosis of the posterior urethra. Additional urinary tract malformations included a prostatic diverticulum, bladder hypertrophy, bilateral hydroureter, and bilateral renal hypoplasia with dysplasia. Autopsy evidence suggested that the urethral stenosis had manifested itself very early during embryologic development and accounted for the associated urinary anomalies. The infant had the physical stigmata, clinical course, and pulmonary hypoplasia commonly observed in "Potter's" or the "renal nonfunction syndrome."
D000015:Abnormalities, Multiple; D006801:Humans; D007231:Infant, Newborn; D007674:Kidney Diseases / Q000151:congenital*; D008297:Male; D013577:Syndrome; D014525:Urethral Stricture / Q000151:congenital* / Q000196:embryology / Q000473:pathology; D014551:Urinary Tract / Q000002:abnormalities* / Q000473:pathology