[Are salicoyl-like analgesics vitamin K antagonists? An interpretation of spontaneous subnormal Quick values].
Prolonged spontaneous prothrombin time values (subnormal Quick values of between 50--70%), such as are encountered frequently in the clinical laboratory, are discussed. The reason for these abnormal values may be traced in part to the ingestion of salicoyl-like analgesics. Acetylsalicylic acid must be considered a low-acting oral anticoagulant which behaves like a vitamin K antagonist. In connection with the frequent use of this substance its interference with the plasmatic blood coagulation system should be considered.
D001777:Blood Coagulation / Q000187:drug effects*; D006801:Humans; D011517:Prothrombin Time; D012459:Salicylates / Q000009:adverse effects*; D014812:Vitamin K / Q000037:antagonists & inhibitors*
D012459:Salicylates; D014812:Vitamin K
Sind salicoylartige Analgetika Vitamin-K-Antagonisten? Eine Deutung der spontanen subnormalen Quickwerte.