Binding of drugs to ion-exchange resins in simulated gastric fluid.
The binding of 13 frequently abused drugs to two ion-exchange resins was studied in simulated gastric fluid. The results were compared with those previously obtained with activated charcoal as the adsorbent. The ion-exchange resins adsorbed the drugs more slowly than activated charcoal, and the binding capacities of the resins were inferior. These ion-exchange resins are unlikely to be very useful in removing drugs from the stomach.
D000327:Adsorption; D002606:Charcoal; D005750:Gastric Juice / Q000032:analysis; D007475:Ion Exchange Resins; D004364:Pharmaceutical Preparations / Q000032:analysis
D007475:Ion Exchange Resins; D004364:Pharmaceutical Preparations; D002606:Charcoal