title: Bicarbonate secretion and solute absorption in forestomach of the llama.
abstract: Bicarbonate appearance in the lumen and its relationship to solute absorption were studied in a Pavlov pouch in the cardiac region of the first compartment of the llama forestomach. HCO3- appearance showed no diurnal variation. HCO3- accumulation was highly dependent on the pH of the solution used. The HCO3- ion probably is formed from CO2 diffusing into the lumen from the serosal side, as a result of cell metabolism and of OH- ions. HCO3- accumulation was closely related to volatile fatty acid (VFA) absorption. The ratio of HCO3- appearance to VFA absorption depended on the pH of the solution. At a pH of 6.6, about 0.1 mol HCO3- and, at a pH of 7.8, 0.9 mol HCO3- appeared per mole absorbed VFA, indicating that at slightly alkaline pH nearly all H+ ions required for the nonionic absorption of VFA appeared to be delivered from the dissociation of H2CO3. Bicarbonate gain and VFA absorption were increased when animals were not fed for 48 h. Sodium absorption was related to VFA as well as water absorption.
mesh_terms: D000042:Absorption; D000818:Animals; D001188:Artiodactyla / Q000378:metabolism*; D001639:Bicarbonates / Q000378:metabolism*; D001692:Biological Transport; D002161:Camelids, New World / Q000378:metabolism*; D002712:Chlorides / Q000378:metabolism; D005215:Fasting; D005232:Fatty Acids, Volatile / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism*; D008297:Male; D012964:Sodium / Q000378:metabolism*; D013997:Time Factors; D014867:Water / Q000378:metabolism
chemical_list: D001639:Bicarbonates; D002712:Chlorides; D005232:Fatty Acids, Volatile; D014867:Water; D012964:Sodium