title: [Leber's optic atrophy - an interdisciplinary study (author's transl)].
abstract: Clinical-neurological, electrocephalographic, ophthalmological and genetic observations of a family with related persons with Leber's optic atrophy is described. 6 male subjects of the altogether ca. 100 members of the family tree stretching over 4 generations were manifestly affected relatives - that is possible carriers, an unusually large number of EEG's were abnormal, and, less often, colour vision disturbances were seen. The results suggest that Leber's optic atrophy is a hereditary neuro-ophthalmological systemic condition, whose most striking symptom is the optic atrophy. The genetic factors of the condition are also discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003118:Color Perception; D004569:Electroencephalography; D005260:Female; D005826:Genetics, Medical; D006801:Humans; D008297:Male; D008875:Middle Aged; D009896:Optic Atrophy / Q000150:complications / Q000175:diagnosis / Q000235:genetics*; D012607:Scotoma; D013577:Syndrome
vernacular_title: Die Lebersche Optikusatrophie. (Eine interdisziplinäre Studie).