[Arterial and venous blood-pressure in the mesenteric circulation of rabbits with combined infusion of secretin and norepinephrine (author's transl)].
Norepinephrine and secretin were infused into V. cava inf. and Art. mesent. sup. with a short intervall and after that immediately successive on rabbits, anesthetized by urethane-chloralose; simultaneously blood-pressure was measured in Aorta abdom., Art. mesent. sup. and V. mesent. sup. Secretin alone does not change blood-pressure; infusion of norepinephrine into V. cava inf. leads to a rise of blood-pressure of about 16% in Aorta abdom., of about 12% in Art. mesent. sup.; in V. mesent. sup. blood-pressure remained unchanged. Although secretin and norepinephrine have a contrary effect on the vascular tonus with cats, in rabbits combined infusion of secretin and norepinephrine caused an increase of blood-pressure not fewer than infusion of norepinephrine alone. Possible haemodynamic mechanisms were discussed.
D000818:Animals; D001012:Aorta, Abdominal; D001794:Blood Pressure / Q000187:drug effects*; D008638:Mesenteric Arteries; D008642:Mesenteric Veins; D009638:Norepinephrine / Q000494:pharmacology*; D011817:Rabbits; D012633:Secretin / Q000494:pharmacology*; D014682:Vena Cava, Inferior; D014690:Venous Pressure / Q000187:drug effects
D012633:Secretin; D009638:Norepinephrine
Die arteriellen und venösen Drucke im Mesenterialkreislauf des Kaninchens bei kombinierter Infusion von Sekretin und Noradrenalin.