[Placental tumors resistant to usual chemotherapy: treatment with cis-diaminedichloroplatinum (2 case reports)].
As cis diaminedichloroplatinum is active in testicular choriocarcinoma, it was logical to try it for placental choriocarcinoma. This drug has been shown very active on two cases of placental choriocarcinoma resisting to methotrexate and actinomycine D. As cis diaminedichloroplatinum is a very toxic drug, it will be given only in the cases resisting to other and less toxic antimitotics.
D000328:Adult; D002822:Choriocarcinoma / Q000188:drug therapy*; D002945:Cisplatin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000188:drug therapy*
D002945:Cisplatin
Tumeurs placentaires résistantes aux chimiothérapies habituelles: traitement par le cis-diaminedichloroplatinum. Deux cas.