Auto analyzer determination of red cell Kell phenotypes in patients with chronic granulomatous disease (CGD) and heterozygous carriers.
One of six boys chronic granulomatous disease was shown to have the rare Kell phenotype, McLeod, by both manual and Auto Analyzer techniques. Using the Auto Analyzer, the red cells of this boy's mother were clearly shown to have weaker expression of k and Kpb antigens than those of the controls, whereas the Kell groups on the father's red cells appeared normal.
D001789:Blood Group Antigens; D005260:Female; D006580:Genetic Carrier Screening; D006105:Granulomatous Disease, Chronic / Q000097:blood* / Q000235:genetics; D006801:Humans; D007626:Kell Blood-Group System; D008297:Male; D010641:Phenotype
D001789:Blood Group Antigens; D007626:Kell Blood-Group System