[Sclero-atrophic keratodermal genodermatosis of the extremities (sclerotylosis) (author's transl)].
The authors report a new case of sclero-atrophic keratodermal genodermatosis of the extremities, which is frequently degenerative. This condition, described by Huriez et al. in 1967, is characterized by symmetric lesions of the hands and feet, sclerodactyly, keratodermia, onychopathy and hypohidrosis. This disease, which is of dominant autosomal transmission, is associated with the MNSs trait, the two genes being probably located on chromosome No. 2.
D005528:Foot; D008040:Genetic Linkage; D006225:Hand; D006801:Humans; D007642:Keratosis / Q000235:genetics*; D008951:MNSs Blood-Group System / Q000235:genetics; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012594:Scleroderma, Localized / Q000235:genetics*
D008951:MNSs Blood-Group System
Génodermatose scléro-atrophiante et kératodermique des extrémités.