Continuous monitoring of urea and inorganic phosphate during hemodialysis: II. Clinical trials.
Ion-selective eletrodes have been used to monitor urea and inorganic phosphate removal during dialysis. The dialysate outlow concentrations from a single pass beside controller were used to compute instantaneous serum concentrations. The urea data are in agreement with a single pool reservoir model; the inorganic phosphate removal was not log-linear, indicating rate limiting intracompartmental transfer. The procedure can be applied to the computation of urea generation rates and thus provide information on the protein catabolism rates of the patient; in addition, the monitor provides continuous checks on the dialyzer performance.
D001322:Autoanalysis; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D010710:Phosphates / Q000097:blood*; D006435:Renal Dialysis; D014508:Urea / Q000097:blood*
D010710:Phosphates; D014508:Urea