[Amniotic fluid tests for fetal lung maturity (author's transl)].
Amniotic fluid specimens of 30 pregnant women were examined for the evaluation of the fetal lung maturity. Three assays were used in parallel: the determination of the lecithin concentration, the estimation of the lecithin/sphingomyelin ratio and the shake test. The results were compared together and with the fetal outcome. The shake test has proved to be sufficient for the exclusion of an immature lung. To avoid failure from false-negative results of the shake test an additional determination of the lecithin/sphingomyelin ratio is recommended, whenever clinical dates give rise to expect a mature lung. The determination of the lecithin concentration has no advantage compared to the lecithin/sphingomyelin ratio. Pathology as candida infection or anecephaly falsifies.
D000649:Amniocentesis; D000653:Amniotic Fluid / Q000032:analysis*; D005260:Female; D005333:Fetus; D006801:Humans; D008168:Lung / Q000254:growth & development*; D010713:Phosphatidylcholines / Q000032:analysis; D011247:Pregnancy; D013109:Sphingomyelins / Q000032:analysis
D010713:Phosphatidylcholines; D013109:Sphingomyelins
Fruchtwasser-Untersuchungen zur Bestimmung der fetalen Lungenreife.