Effect of hydrocortisone on phenylhydrazine-induced Heinz-body anemia.
The effect of hydrocortisone on phenylhydrazine-induced anemia has been examined in adrenalectomized rats. The extent of hemolysis in adrenalectomized rats treated with phenylhydrazine was significantly higher than in normal and adrenalectomized rats supplemented with hydrocortisone.
D000315:Adrenalectomy; D000818:Animals; D006366:Heinz Bodies / Q000187:drug effects*; D006454:Hemoglobins / Q000378:metabolism; D006461:Hemolysis / Q000187:drug effects*; D006854:Hydrocortisone / Q000494:pharmacology*; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010659:Phenylhydrazines / Q000494:pharmacology*; D051381:Rats; D013154:Spleen / Q000187:drug effects; D013997:Time Factors
D006454:Hemoglobins; D010659:Phenylhydrazines; D006854:Hydrocortisone