[Quantitative cytochemical study of local immunostimulation of the respiratory mucosae by mineral spa water (author's transl)].
After non-specific stimulation (by mineral spa water) of the secretion of IgA by the respiratory tract of rabbits, the animals were killed and a study made of the number of plasmocytes per 500 diameter field by phase contrast microscopy. The number of plasmocytes was markedly increased on the 15th day and remained 5 times higher than in control animals on the 100th day. Immunocytochemical labelling by the secretory anti-IgA Fab fraction confirmed these data electron microscopically.
D000818:Animals; D002452:Cell Count; D007070:Immunoglobulin A / Q000096:biosynthesis*; D007071:Immunoglobulin A, Secretory / Q000096:biosynthesis*; D008854:Microscopy, Electron; D008900:Mineral Waters; D009297:Nasal Mucosa / Q000166:cytology / Q000276:immunology* / Q000378:metabolism; D010950:Plasma Cells / Q000166:cytology; D011817:Rabbits
D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D008900:Mineral Waters
Etude cytochimique quantitative de l'immunostimulation locale des muqueuses respiratoires par une eau thermale.