Estimation of Absidia ramosa infection in the brain and kidneys of cortisone-treated mice by chitin assay.
Chitin assay was used to measure Absidia ramosa infection in the brain and kidneys of cortisone-treated mice. Mice dying 3 days after challenge had brain and kidney infection but normal renal function as determined by measurement of blood urea levels. Mice dying 5 or 6 days after challenge had infection in the kidneys but not the brain and were uraemic.
D000818:Animals; D001921:Brain / Q000382:microbiology*; D001923:Brain Chemistry; D002686:Chitin / Q000032:analysis*; D003348:Cortisone / Q000009:adverse effects; D007668:Kidney / Q000032:analysis / Q000382:microbiology*; D008297:Male; D051379:Mice; D009090:Mucorales / Q000254:growth & development*; D009091:Mucormycosis / Q000378:metabolism / Q000382:microbiology*; D014508:Urea / Q000097:blood
D002686:Chitin; D014508:Urea; D003348:Cortisone