Endopeptidase activity of the brush border of human enterocyte.
Succinyl-trialanine-p-nitroanilide (Suc-Ala3-pNA) has been described earlier as a convenient substrate for pancreatic elastase which is not split by trypsin and chymotrypsin. An enzyme activity splitting Suc-Ala3-pNA has been found in the supernatant of the mucous membrane of human small intestine homogenized with Triton X-100.
D002462:Cell Membrane; D006801:Humans; D007413:Intestinal Mucosa / Q000166:cytology / Q000201:enzymology*; D007583:Jejunum; D008871:Microvilli; D010447:Peptide Hydrolases / Q000378:metabolism*
D010447:Peptide Hydrolases