Allergic orchitis lesions are adoptively transferred from vasoligated guinea pigs to syngeneic recipients.
Histopathology typical of allergic orchitis developed in testes of inbred guinea pigs 16 months after vasoligation. A similar histopathology was found in unoperated testes after unilateral vasoligation. Peritoneal exudate cells from vasoligated guinea pigs transferred identical lesions to syngeneic recipients. The testicular lesions in long-term vasoligated guinea pigs have an immunological basis.
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D001327:Autoimmune Diseases / Q000209:etiology* / Q000473:pathology; D005122:Exudates and Transudates / Q000276:immunology; D006168:Guinea Pigs; D007116:Immunization, Passive; D008297:Male; D009920:Orchitis / Q000209:etiology / Q000276:immunology* / Q000473:pathology; D014659:Vasectomy / Q000009:adverse effects*