[Sialic acid content of human thyroglobulins iodinated at different levels (author's transl)].
Sialic acid and iodine content were measured on 53 thyroglobulins from normal and pathological tissues. Sialic acid is significantly decreased in isolated cold nodules, and highly reduced in hot nodules and toxic adenomas. In these pathological situations, sialic acid defect could interfere with the iodination of the molecule.
D006801:Humans; D007455:Iodine / Q000378:metabolism*; D012794:Sialic Acids / Q000378:metabolism*; D013954:Thyroglobulin / Q000378:metabolism*; D013959:Thyroid Diseases / Q000378:metabolism*; D013961:Thyroid Gland / Q000378:metabolism*
D012794:Sialic Acids; D013954:Thyroglobulin; D007455:Iodine
Teneur en acide sialique de thyroglobulines humaines iodées à différents niveaux.