Isolation of tridecaptins A, B and C (studies on antibiotics from the genus Bacillus. XXIII).
Three new antibiotics, tridecaptins A, B and C, were isolated from culture broths of strains of Bacillus polymyxa AR-110, B-2 and E-23, respectively. All are acyl tridecapeptides differing from each other in the fatty acid components and amino acid residues. They are weakly active against Gram-negative and Gram-positive bacteria in vitro and in vivo.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000302:isolation & purification* / Q000494:pharmacology; D001407:Bacillus / Q000378:metabolism*; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D002627:Chemistry, Physical; D006020:Glycopeptides / Q000096:biosynthesis / Q000302:isolation & purification / Q000494:pharmacology; D051379:Mice; D008813:Mice, Inbred ICR; D013171:Spores, Bacterial
D000596:Amino Acids; D000900:Anti-Bacterial Agents; D006020:Glycopeptides