title: [Isoenzyme P of N-acetyl-beta-glucosaminidase in sera from patients with liver diseases (author's transl)].
abstract: The isoenzyme P of N-Acetyl-beta-Glucosaminidase (beta-NAG) is demonstrated in sera from healthy persons and patients with acute and chronic liver diseases by electrofocusing in polyacrylamide gel. Elevation of isoenzyme P is observed only together with elevation of Glutamate-Pyruvate-Transaminase (GPT) in patients with acute and chronic liver diseases of different etiology and activity. The correlation between isoenzyme P and GPT is significant. On the contrary whole beta-NAG is elevated due the activity of the mesenchymal reaction in the injured liver tissue, not related to enzymes of the cytosol like GPT.
mesh_terms: D000118:Acetylglucosaminidase / Q000097:blood*; D000208:Acute Disease; D000410:Alanine Transaminase / Q000097:blood; D002908:Chronic Disease; D006596:Hexosaminidases / Q000097:blood*; D006801:Humans; D007525:Isoelectric Focusing; D007527:Isoenzymes / Q000097:blood*; D008107:Liver Diseases / Q000201:enzymology*
chemical_list: D007527:Isoenzymes; D000410:Alanine Transaminase; D006596:Hexosaminidases; D000118:Acetylglucosaminidase
vernacular_title: Isoenzym P der N-Acetyl-beta-Glucosaminidase im Serum bei Leberkranken.