[Increase in the oleandomycin distribution coefficient at the extraction stage by using electron carrier-acceptors].
A possibility of increasing the distribution coefficient of oleandomycin on its extraction from the aqueous solution into the organic phase containing an electron carrier-acceptor was shown. It was found that the level of the oleandomycin equilibrium shift into the organic phase depended on the carrier nature, i. e. the donor-acceptor interaction of the carrier and the antibiotic. It was shown that the oleandomycin fermentation broth contained non-identified admixtures, the interaction of which with the antibiotic was higher than its interaction with the acceptor-carriers tested.
D000085:Acetates; D004583:Electrons; D007202:Indicators and Reagents; D009827:Oleandomycin / Q000302:isolation & purification*; D012996:Solutions
D000085:Acetates; D007202:Indicators and Reagents; D012996:Solutions; D009827:Oleandomycin
Ob uvelichenii koéffitsienta raspredeleniia oleandomitsina na stadii ékstraktsii pri ispol'zovanii perenoschikov-aktseptorov élektronov.