title: Role of vagus in thermal panting.
abstract: In dogs anaesthetised with pentobarbitone sodium, raising the body temperature from 37 degrees C to 42 degrees C increased the rate of respiration and pulmonary ventilation but decreased the tidal volume. A similar change though of a lower magnitude, was observed in these parameters after cold blocking the vagi. At 40 degrees C body temperature, however, the vagal block was not effective in reducing the rate. The significance of hyperthermic panting mechanism dominating the Hering-Breuer mechanism at 40 degrees C has been discussed. It has been postulated that the vagi carry temperature dependent afferents that have effect opposite to the Hering-Breuer reflex. At 42 degrees C when respiratory failure usually sets in the temperature regulating function of respiration is the last to be lost.
mesh_terms: D000818:Animals; D001831:Body Temperature; D001833:Body Temperature Regulation; D004285:Dogs; D005260:Female; D008297:Male; D012018:Reflex / Q000502:physiology; D012119:Respiration; D013990:Tidal Volume; D014630:Vagus Nerve / Q000502:physiology*