title: The experimental infection of ponies with contagious equine metritis.
abstract: Four pony mares were readily infected with the organism of contagious equine metritis by intracervical inoculation and one by coitus with an infected stallion. Infected mares developed an acute endometritis with local destruction of the endometrial epithelium. In 2 experimentally infected mares, infection appeared to have been spontaneously eliminated from the genital tract within 3 to 4 weeks. A third mare however remained persistently infected in the clitoral fossa over a long period and was a symptomless carrier. Four pony stallions were readily infected in the urethral fossa and the organism survived for varying periods without giving rise to any signs of infection. From 2 of these animals it appeared eventually to have been eliminated spontaneously. An experimentally infected stallion transmitted infection to a healthy mare by coitus. Bacteriological examination of infected pony stallions may occassionally give false negative results and fail to reveal the organism in the external genitalia. Repeated bacteriological examinations need to be undertaken before it can be concluded that a stallion is free of infection.
mesh_terms: D000818:Animals; D001419:Bacteria / Q000302:isolation & purification; D001424:Bacterial Infections / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D002584:Cervix Uteri / Q000382:microbiology; D002987:Clitoris / Q000382:microbiology; D004716:Endometritis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000382:microbiology / Q000473:pathology; D006736:Horses; D008297:Male; D014521:Urethra / Q000382:microbiology; D014522:Urethral Diseases / Q000382:microbiology / Q000662:veterinary; D014599:Uterus / Q000473:pathology