title: Simplified management of pregnancy complicated by diabetes.
abstract: Simple methods for the management of pregnancy complicated by diabetes are described. Emphasis was placed on keeping patients out of hospital, good control of diabetes and vaginal delivery at 38 weeks: using these methods, there were nine perinatal deaths in a consecutive series of 101 pregnancies complicated by diabetes. Four of the perinatal deaths were due to the respiratory distress syndrome. The patients whose diabetes was diagnosed during pregnancy had significantly heavier babies (18 pregnancies, mean birth weight 3337 g) than the established diabetics (83 pregnancies, mean weight 3011 g) despite significantly lower fasting blood glucose levels in the former and similar mean gestational ages at delivery. Mean fasting blood glucose levels for the whole series during the first, second and third trimesters were 9.0, 6.7 and 5.6 mmol/l respectively. The mean duration of antenatal stay in hospital for complications related to diabetes was 29 days. Diabetic retinopathy did not seem to be adversely affected by pregnancy.
mesh_terms: D001724:Birth Weight; D001786:Blood Glucose / Q000032:analysis; D036861:Delivery, Obstetric; D003930:Diabetic Retinopathy / Q000209:etiology; D005260:Female; D005313:Fetal Death / Q000150:complications; D006760:Hospitalization; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000150:complications; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000150:complications / Q000188:drug therapy / Q000628:therapy*
chemical_list: D001786:Blood Glucose; D007328:Insulin