title: [Peroxidase deficiency in neutrophils in systemic mastocytosis (author's transl)].
abstract: A case associating a systemic mastocytosis and an acquired myeloperoxidase deficiency is reported. The myeloperoxydase deficiency is studied by cytochemical techniques in optical and electron microscopy and confirmed by biochemical measures. An important defect in bactericidal and candidacidal activity is demonstrated in vitro in P.N.M. The authors discuss the links between the two anomalies which might bring one more argument for the common origin of both granulocytes and mastocytes.
mesh_terms: D001773:Blood Cells / Q000201:enzymology; D001853:Bone Marrow / Q000201:enzymology*; D005260:Female; D006098:Granulocytes / Q000201:enzymology; D006801:Humans; D008875:Middle Aged; D009504:Neutrophils / Q000201:enzymology*; D010544:Peroxidases / Q000032:analysis / Q000172:deficiency*; D014582:Urticaria Pigmentosa / Q000201:enzymology*
chemical_list: D010544:Peroxidases
vernacular_title: Déficit en peroxydase des granulocytes neutrophiles au cours d'une mastocytose diffuse.