USP dissolution IV: comparison of methods.
The hydrodynamics of four dissolution apparatus--viz., the USP basket, the USP paddle, the stationary basket-spinning filter, and the USP disintegration apparatus, were characterized. At higher velocities, the relationship between the intrinsic dissolution rate constant and linear velocity was parabolic rather than linear.
D002626:Chemistry, Pharmaceutical / Q000295:instrumentation / Q000379:methods*; D007700:Kinetics; D010602:Pharmacopoeias as Topic; D012995:Solubility; D012997:Solvents; D014481:United States
D012997:Solvents