title: [Effect of normal microflora, age and sex of rats on serum IgG2 levels].
abstract: Germfree and conventional rats of Fisher inbred strain and mongrel animals were used in this study. IgG2 was separated from the pool serum of mongrel rats, and anti-IgG2 was obtained by hyperimmunization of rabbits. IgG2 content was determined by in the sera of different groups of rats radial immunodiffusion. There was 5.4 times less IgG2 in the sera of Fisher germfree rats than in conventional Fisher animals; its level in female animals was by 10--15% higher than in the male ones. The first hours after birth the IgG2 level was the same in the sera of all the newborn rats irrespective of its amount in the maternal sera.
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D005260:Female; D005856:Germ-Free Life; D007074:Immunoglobulin G / Q000032:analysis*; D007774:Lactation; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors
chemical_list: D007074:Immunoglobulin G
vernacular_title: Vliianie normal'noĭ mikroflory, vozrasta i pola krys na uroven' IgG2 v syvorotke krovi.