Radiation dose and labeling of hippuran.
Renal morphology and renal function were studied with iodine-123-hippurate in 98 patients with various renal diseases. Sequential scintigraphy with iodine-123-hippurate demonstrates much better renal blood flow, morphology and function than iodine-131-hippurate. A method of labeling hippurate in a short time (2 h) with high efficiency (95--100%) is described. Radiation exposure to various organs was calculated and significant differences in radiation exposure to the thyroid are demonstrated.
D006626:Hippurates; D006801:Humans; D007457:Iodine Radioisotopes; D007553:Isotope Labeling / Q000379:methods*; D007674:Kidney Diseases / Q000000981:diagnostic imaging*; D011829:Radiation Dosage; D011859:Radiography; D011877:Radionuclide Imaging; D014570:Urologic Diseases / Q000000981:diagnostic imaging
D006626:Hippurates; D007457:Iodine Radioisotopes