Blockade of central and peripheral generation of prostaglandins explains the antialgic effect of aspirin like drugs.
D000082:Acetaminophen / Q000627:therapeutic use; D000818:Animals; D001241:Aspirin / Q000627:therapeutic use*; D002351:Carrageenan; D006930:Hyperalgesia / Q000139:chemically induced / Q000188:drug therapy*; D006941:Hyperesthesia / Q000188:drug therapy*; D007213:Indomethacin / Q000627:therapeutic use; D010615:Phenacetin / Q000627:therapeutic use; D011448:Prostaglandin Antagonists; D011453:Prostaglandins / Q000096:biosynthesis; D051381:Rats
D011448:Prostaglandin Antagonists; D011453:Prostaglandins; D000082:Acetaminophen; D002351:Carrageenan; D010615:Phenacetin; D001241:Aspirin; D007213:Indomethacin