Synthesis and antimicrobial properties of 3-substituted 1,2-benzisothiazole 1,1-dioxides.
Twenty aromatic alcohols and thiols were derivatized by reaction with 3-chloro-1,2-benzisothiazole 1,1-dioxide. The resulting 3-substituted 1,2-benzisothiazole 1,1-dioxides were tested against Staphylococcus aureus, Salmonella typhosa, and Aspergillus niger, and their activities were compared with the activities of the precursors.
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D001234:Aspergillus niger / Q000187:drug effects; D012485:Salmonella typhi / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D013844:Thiazoles