Prognostic significance of histologic subdivision of Hodgkin's disease nodular sclerosis.
Sixty-seven patients with nodular sclerosis (Hodgkin's disease stages I and II) have been subclassified according to the cellular composition and the amount of fibrosis. Predominance of mature lymphocytes and rarity of Reed Sternberg cells were associated with less extensive disease at presentation and more favourable outcome. A less definite correlation to the amount of fibrosis was found.
D001772:Blood Cell Count; D005260:Female; D005500:Follow-Up Studies; D006689:Hodgkin Disease / Q000473:pathology* / Q000532:radiotherapy; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D012598:Sclerosis