[Treatment of mycosis fungoides by PUVAtherapy. Report on 18 cases (author's transl)].
A group of 18 patients with mycosis fungoides (M.F.) was treated by PUVAtherapy. According to VanScott classification, they have been set in:--5 parapsoriasis in large plaques = 5 stages I;--6 stages II;--3 stages III;--2 stages IV;--1Sézary syndrom.--1 erythrodermia. There was complete clearing of 12 patients (66 p. 100); 2 patients (11 p. 100) improved cutaneous lesions without a complete clearing, and there was no response to treatment for 3 patients (22 p. 100) (1 with erythrodermia, 1 with Sézary syndrom and 1 stage IV, and 1 forsaking). The method applied here was different in several points: orally administered methoxalen were given according to the body area (mg/m2) and some of the patients had twice a day puvatherapy. Puvatherapy seems to be the least dangerous and most effective treatment for the patients in the early stages of mycosis fongoides (I, II) and nitrogen mustard, electron therapy, corticoids and even mono- or polychimiotherapy could be associated to puvatherapy, if necessary, for the stages III and IV.
D000368:Aged; D003374:Coumarins / Q000627:therapeutic use*; D005260:Female; D005363:Ficusin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000188:drug therapy*; D010778:Photochemotherapy; D012878:Skin Neoplasms / Q000188:drug therapy*; D014467:Ultraviolet Therapy
D003374:Coumarins; D005363:Ficusin
Traitement du mycosis fongoïde par la puvathérapie. a propos de 18 cas.