Function of phagocytosis and intracellular killing of peripheral neutrophils in Kawasaki disease.
NBT (Nitroblue Tetrazolium) test was performed in 17 patients with Kawasaki disease to examine the function of phagocytosis and intra-cellular killing of neutrophils. The value was high compared to other pediatric patients. Activation with Proteus OX-2 antigen before NBF test showed a significant higher level than other proteus antigens, which correspond in serum level. With previous electronmicroscopic observation of rickettsia-like body in biopsy specimen, these findings suggest the existence of an agent in Kawasaki disease which shares antigenicity with Proteus OX-2.
D000942:Antigens, Bacterial; D001770:Blood Bactericidal Activity; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008206:Lymphatic Diseases / Q000276:immunology*; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000276:immunology*; D009504:Neutrophils / Q000276:immunology*; D009580:Nitroblue Tetrazolium; D010587:Phagocytosis; D011511:Proteus / Q000276:immunology; D013997:Time Factors
D000942:Antigens, Bacterial; D009580:Nitroblue Tetrazolium