Ethnic variation of genetic disease: roles of drift for recessive lethal genes.
Using Wright's distribution of gene frequencies for a recessive lethal gene, a method is given to analyze the probability that any particular gene frequency is greater than a given threshold gene frequency. The method is introduced to analyze the plausibility of drift for explaining observed data.
D003201:Computers; D005260:Female; D005787:Gene Frequency; D005804:Genes, Lethal; D005808:Genes, Recessive; D006801:Humans; D008064:Lipidoses / Q000235:genetics; D008297:Male; D008433:Mathematics; D008954:Models, Biological; D044469:Racial Groups