Loss of amino acids during hemodialysis: quantitative and qualitative investigations.
In three patients the total amino acid losses (free plus peptide-bound) in dialyzate have been assayed by means of gas-liquid chromatography. During a period 3--4 months the average losses varied from 115--178 mg per kg of body weight per dialysis treatment. The weekly mean essential amino acid losses amounted to 3--4% of the dietary intake. The concentrations in the dialyzate of non-essential amino acid fell considerably during the dialysis procedure, whereas the concentrations of most of the essential amino acids remained at a fairly constant level. It is concluded that considerable quantitative but no qualitative differences exist between the patients with respect to amino acid losses.
D000596:Amino Acids / Q000032:analysis*; D002849:Chromatography, Gas; D006801:Humans; D008297:Male; D006435:Renal Dialysis; D013997:Time Factors
D000596:Amino Acids