title: Species-specific aggregation factor in sponges. XIII. Entire and core structure of the large circular proteid particle from Geodia cydonium.
abstract: High-molecular weight particles have been isolated from the sponge Geodica cydonium. In the "native" from these particles consist of a spherical center and have 25-30 filaments attached to it. The core structure of the particles is assembled of a central circle and 25 radially-arranged filaments. The core structure is obtained from the entire structure by incubation in a medium, containing a non-ionic detergent and EDTA. The molecular weight of the enitre structure was in the range of 1.4 X 10(9) daltons or more and of the core structure 6.1 x 10(8) daltons. Two functional proteins are released from the "native" particles: the aggregation factor and the sialytransferase.
mesh_terms: D000818:Animals; D002449:Cell Aggregation; D002499:Centrifugation, Density Gradient; D002850:Chromatography, Gel; D003902:Detergents / Q000494:pharmacology; D008970:Molecular Weight; D011161:Porifera / Q000032:analysis / Q000648:ultrastructure*; D011506:Proteins; D012799:Sialyltransferases; D013045:Species Specificity
chemical_list: D003902:Detergents; D011506:Proteins; D012799:Sialyltransferases