Scanning electron microscopy of the spreading of barium sulfate suspensions on the gastric mucosa of the rat. Effect of wetting agents, bile salt and lecithine.
Scanning electron microscopy was performed on the rat stomach mucosa after application of BaSO4 and three barium-containing commercial contrast media. The degree of flocculation was assessed; flocculation could be prevented by using synthetic wetting agents and by physiologic, natural emulsifiers, sodium taurocholate and lecithine.
D000818:Animals; D001466:Barium Sulfate / Q000008:administration & dosage; D001647:Bile Acids and Salts / Q000494:pharmacology; D004357:Drug Synergism; D005260:Female; D005427:Flocculation; D005753:Gastric Mucosa / Q000187:drug effects*; D008297:Male; D008855:Microscopy, Electron, Scanning / Q000379:methods*; D010713:Phosphatidylcholines / Q000494:pharmacology; D011092:Polyethylene Glycols / Q000494:pharmacology; D051381:Rats; D013500:Surface Tension; D014906:Wetting Agents / Q000494:pharmacology
D001647:Bile Acids and Salts; D010713:Phosphatidylcholines; D014906:Wetting Agents; D001466:Barium Sulfate; D011092:Polyethylene Glycols