Effect of oestrogen on fetal survival in the rabbit.
Pregnant rabbits (Day 18) were treated i.m. for 3 days with 10 microgram oestradiol 17beta/kg. The number of dead fetuses was significantly greater than in the control animals but corpus luteum weight and peripheral progesterone concentrations were not affected. Fetal death was therefore not due to luteolysis.
D000818:Animals; D003338:Corpus Luteum / Q000187:drug effects; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D005328:Fetal Viability / Q000187:drug effects*; D009929:Organ Size / Q000187:drug effects; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D011817:Rabbits
D011374:Progesterone; D004958:Estradiol