Non-volatile N-nitroso compounds in human feces.
A bacterial mutagen has been detected in ether extracts of freeze-dried feces of humans on Western diet. Several types of evidence suggest that nitroso compounds are present in human feces and the mutagen could be a nitroso compound. Ascorbic acid supplement in the diet reduces the levels of both the mutagens and nitroso compounds in the feces.
D001205:Ascorbic Acid / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D004032:Diet; D005243:Feces / Q000032:analysis*; D006801:Humans; D009153:Mutagens / Q000302:isolation & purification; D009603:Nitroso Compounds / Q000032:analysis*; D013997:Time Factors
D009153:Mutagens; D009603:Nitroso Compounds; D001205:Ascorbic Acid