[Influence of oxianthraquinones on the crystallization of calcium oxalate and calcium phosphate: dissolution of calciumcontaining urinary calculi (author's transl)].
Ruberythric acid and alizarin glucuronide, the biologic secretion product obtained from the alizarin derivative, stop the crystallization of calcium oxalate and calcium phosphate in the physiologic milieu of the urine. This effect is thought to be due to a soluble alizarin glucuronide: calcium chelate (2:1 mol). From this finding, we deduce that the solubility of calcium oxalate and calcium phosphate in the urine of humans can be increased through the oral administration of oxianthraquinone.
D000880:Anthraquinones / Q000494:pharmacology*; D002118:Calcium / Q000032:analysis*; D002130:Calcium Phosphates / Q000378:metabolism; D003460:Crystallization; D010070:Oxalates / Q000378:metabolism; D012995:Solubility; D014545:Urinary Calculi / Q000378:metabolism*
D000880:Anthraquinones; D002130:Calcium Phosphates; D010070:Oxalates; D002118:Calcium
Einfluss von Oxianthrachinonen auf die Kristallisation von Calciumoxalat und -phosphat. Ein Beitrag zur Auflösung calciumhaltiger Harnsteine.