Detection of hematoporphyrin fluorescence during fiberoptic bronchoscopy to localize early bronchogenic carcinoma.
Photoelectric detection of fluorescence from hematoporphyrin-containing "occult" bronchogenic carcinoma is a potentially useful technique for localizing and delineating such cancers. A method is presented which would enable use of a fluorescence-detection system simultaneously with conventional illumination during flexible bronchofiberscopic examination. Preliminary data suggest that quantities of hematoporphyrin as small as 5 picograms can be detected on the surface of tumors by this method.
D001999:Bronchoscopy; D002283:Carcinoma, Bronchogenic / Q000175:diagnosis*; D005336:Fiber Optic Technology; D005453:Fluorescence; D006415:Hematoporphyrins; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D008954:Models, Biological
D006415:Hematoporphyrins