[Effect of fatty acid triglycerides on lipogenesis and the makeup of plasma, fatty tissue and erythocyte membrane fatty acids in rats].
The fatty acids middle-chain triglycerides (FAMCT) may be considered as a possible component of alimentary mixtures intended to lower the energy-giving efficiency of the nutritional ration. They do not join the tissue lipids, whereas their reconstruction into long-chain fatty acids requires an additional expenditure of energy. These facts were confirmed by the results obtained in tests on rats. Feeding of growing rats for 5 weeks on a ration containing 12 per cent of the FAMCT on condition of a sufficient administration of polyunsaturated fatty acids (PUFA) through addition of sunflower seed oil led to a significant fall of the body mass gain by comparison with that in rats receiving a ration whose main source of fat was lard. An increased tryglycerides synthesis in the liver was not accompanied by their accumulation in the organ. The triglycerides level in the serum was up. An analysis of the fatty acids composition in the epididymitic fatty tissue, plasma and erythrocytes confirmed that the FAMCT C2-fragments developing during metabolization are used up chiefly in lipogenesis, one of the basic products of which is palmitic acid. The metabolization of FAMC with sufficient PUFA proportion in the ration does not derange the plastic function of fat in the organism, i.e, securing biosynthesis of lipid components of the membranes.
D000273:Adipose Tissue / Q000032:analysis*; D000818:Animals; D001835:Body Weight; D004041:Dietary Fats / Q000378:metabolism; D002149:Energy Intake; D004910:Erythrocyte Membrane / Q000032:analysis*; D004912:Erythrocytes / Q000032:analysis*; D005227:Fatty Acids / Q000032:analysis*; D008055:Lipids / Q000096:biosynthesis*; D010743:Phospholipids / Q000032:analysis; D010949:Plasma / Q000032:analysis*; D051381:Rats; D013997:Time Factors; D014280:Triglycerides / Q000378:metabolism*
D004041:Dietary Fats; D005227:Fatty Acids; D008055:Lipids; D010743:Phospholipids; D014280:Triglycerides
Vliianie triglitseridov zhirnykh kislot na lipogenez i sostav zhirnykh kislot plazmy, zhirovoĭ tkani i membran éritrotsitov u krys.