Effect of antigen dose on the secondary IgE response in BN rats.
Inbred Brown Norway rats were immunized at day 0 with a single dose of ovalbumin and 1 mg A1(OH)3. Various doses of ovalbumin without adjuvant were given at day 28. The secondary IgE antibody was antigen dose-dependent. Total serum IgE levels decreased after immunization and during the IgE antibody response.
D000536:Aluminum Hydroxide / Q000276:immunology; D000818:Animals; D004306:Dose-Response Relationship, Immunologic; D007073:Immunoglobulin E / Q000096:biosynthesis*; D007156:Immunologic Memory; D008297:Male; D010047:Ovalbumin / Q000276:immunology*; D051381:Rats; D011914:Rats, Inbred BN
D007073:Immunoglobulin E; D000536:Aluminum Hydroxide; D010047:Ovalbumin