The effects of ischemia on the electrical and contractile activities of the canine small intestine.
The effects of ischemia on the electrical and contractile activites of the small bowel were studied in dogs. Ischemia due to arterial occlusion abolished the contractile activity and made the regular rhythm of the pacesetter potential (PP) irregular. Revascularization within 3 hours restored the contractile activity and the PP rhythm. With longer periods of ischemia, revascularization did not restore contractile activity, and the PP pattern remained irregular or slow.
D000818:Animals; D003250:Constriction; D004285:Dogs; D004594:Electrophysiology; D005071:Evoked Potentials; D005769:Gastrointestinal Motility; D007421:Intestine, Small / Q000098:blood supply / Q000503:physiopathology*; D007511:Ischemia / Q000209:etiology / Q000503:physiopathology*; D008638:Mesenteric Arteries