Peripheral vascular dynamics studied by calcium ion inhibition.
The study of peripheral vasomotility through inhibition of parietal smooth muscle cells is of great clinical interest for both diagnostic and therapeutic reasons. It permits the differentiation of the functional clinical forms from the organic. And in organic forms, once any spastic component is eliminated, it determines the site and severity. On the basis of these premises we have developed a test for the study of vascular dynamics based on the use of nifedipine as antagonist of calcium ions.
D000328:Adult; D000368:Aged; D001161:Arteriosclerosis / Q000503:physiopathology; D002118:Calcium / Q000037:antagonists & inhibitors*; D003925:Diabetic Angiopathies / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D009130:Muscle, Smooth / Q000187:drug effects; D009543:Nifedipine / Q000494:pharmacology*; D010992:Plethysmography, Impedance; D011725:Pyridines / Q000494:pharmacology*; D013997:Time Factors; D014666:Vasomotor System / Q000187:drug effects* / Q000503:physiopathology
D011725:Pyridines; D009543:Nifedipine; D002118:Calcium