title: Cellular basis of anoxic-ischemic brain injury.
abstract: Anoxic-ischemic cerebral disease is an important primary cause of morbidity and mortality, and also complicates a number of systemic diseases. Its clinical manifestations, such as hemiparesis and coma, represent cellular injury sustained by the complex, inhomogeneous brain. An understanding of the nature and pattern of anoxic-ischemic cerebral injury, and of the logical basis for avenues of therapy, is necessary to the management of patients with the various anoxic-ischemic disorders.
mesh_terms: D001923:Brain Chemistry; D001929:Brain Edema / Q000150:complications; D001930:Brain Injuries / Q000150:complications*; D006801:Humans; D002534:Hypoxia, Brain / Q000150:complications*; D002546:Ischemic Attack, Transient / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D009410:Nerve Degeneration