Aerosol distribution in the nose.
Using a cast of the human nose the intranasal distribution of drugs, delivered from pressurized aerosols and nebulizers was studied. The results indicate that a pressurized aerosol should be used twice in each nostril to give an acceptable drug distribution, and also that an automized pump is preferable for a plastic-bottle nebulizer with regard to drug distribution.
D000281:Administration, Intranasal; D000336:Aerosols / Q000008:administration & dosage*; D006801:Humans; D009296:Nasal Cavity / Q000378:metabolism*; D014018:Tissue Distribution
D000336:Aerosols