[Functional changes in the respiratory system in acquired heart defects].
A total of 52 patients were examined, 8 out of them healthy and 44 patients with acquired valves defects without accompanying pulmonary and other diseases. The indices of external respiration, alveolar-arterial gradients for O2 and CO2 were followed up as well as diffusion capacity of lungs and its components, acid-alkaline balance, functional and real shunts in the pulmonary circulation, etc. The summed up results revealed that considerable disturbances in external respiration, leading mainly to a restrictive ventilatory syndrome, developed with the lesion of myocardium and valve apparatus of the heart. The values of diffusion lung capacity for CO and its components--Dm and Vc are decreased. O2 and CO2 metabolism was disturbed. The results pointed to a moderately manifested hypoxemia, marked elevation of alveolar-arterial gradients for O2 and presence of respiratory alkalosis. A considerable increase in the functional and real shunts of the lungs were established, manifestations of the disturbed pulmonary ventilation and hemodynamics in the pulmonary circulation.
D000136:Acid-Base Equilibrium; D000328:Adult; D005260:Female; D006349:Heart Valve Diseases / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010313:Partial Pressure; D012129:Respiratory Function Tests; D012137:Respiratory System / Q000503:physiopathology*; D012214:Rheumatic Heart Disease / Q000503:physiopathology
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