Tracer priming the bicarbonate pool.
We have described a technique whereby the time necessary to reach an equilibrium enrichment of expired CO2 during a primed-constant infusion of [U-13C]glucose was shortened from 7 to 8 h to 1 hour or less. We applied the theory of the primed-constant infusion technique to the bicarbonate pool, with the "constant infusion" of labeled carbon dioxide originating from oxidation of the infused [13C]glucose rather than from a labeled infusion of bicarbonate.
D001639:Bicarbonates / Q000378:metabolism*; D002245:Carbon Dioxide; D005947:Glucose / Q000378:metabolism*; D007263:Infusions, Parenteral; D013997:Time Factors
D001639:Bicarbonates; D002245:Carbon Dioxide; D005947:Glucose