Diffuse unilateral subacute neuroretinitis.
Thirty-six young healthy patients developed a peculiar clinical syndrome affecting only one eye. The early stage of the disease was characterized by visual loss, vitritis, mild papilledema, and successive crops of multiple, evanescent, gray-white, deep, retinal lesions. Over a period of many months there developed widespread, diffuse and focal depigmentation of the pigment epithelium, retinal arterial narrowing, optic atrophy, severe visual loss, and electroretinographic changes. A motile, subretinal round worm, probably a Toxocara, was observed in two patients.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005451:Fluorescein Angiography; D007839:Functional Laterality; D006801:Humans; D008297:Male; D009349:Nematode Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D012160:Retina / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology; D012173:Retinitis / Q000175:diagnosis / Q000469:parasitology* / Q000473:pathology; D013577:Syndrome; D013827:Thiabendazole / Q000627:therapeutic use; D014792:Visual Acuity
D013827:Thiabendazole