title: [Effect of a calcium-deficient, phosphate- or ammonia-rich diet on the development and mineral metabolism of growing miniature pigs].
abstract: The metaphylaxis of renal calculi in form of partial withdrawal of Ca and the nutrition rich in phosphate or NH4C1 in children was disputed and not ascertained by animal experiments. For this purpose growing female dwarf pigs got a semisynthetic ration with 1 g Ca and 23 g P, respectively, or 15 g NH4C1 per kg dry feeding mass during 168 days. The dwarf pigs fed poor in Ca had a reduced increase of body-weight of 30%, the pigs fed rich in P and NH4C1 a reduced increase of body-weight of 11 and 16%, respectively, compared with the control dwarf pigs. The feeding regime chosen has no significant influence on the Ca-, P-, Cu-, and Mn-state of the dwarf pigs (alpha greater than 0.05). Only the animals with deficiency of a Ca statistically ascertained stored more Zn in the liver than the control animals. The applied NH4C1 as well as the medicament Ammonchlor SSW contained traces of Cd. Concerning the lacking significant changes of metabolism on account of the retardation of growth conditioned by therapy it cannot be concluded that there is possible a metaphylaxis of the lithiasis in children by partial withdrawal of Ca or additions of P and NH4C1, respectively.
mesh_terms: D000641:Ammonia / Q000008:administration & dosage* / Q000378:metabolism; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001835:Body Weight; D001921:Brain / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D002136:Calcium, Dietary / Q000008:administration & dosage*; D003300:Copper / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008345:Manganese / Q000378:metabolism; D009747:Nutritional Physiological Phenomena; D010710:Phosphates / Q000008:administration & dosage* / Q000378:metabolism; D013045:Species Specificity; D013552:Swine / Q000254:growth & development*; D015032:Zinc / Q000378:metabolism
chemical_list: D002136:Calcium, Dietary; D010710:Phosphates; D008345:Manganese; D000641:Ammonia; D003300:Copper; D015032:Zinc; D002118:Calcium
vernacular_title: Der Einfluss einer kalziumarmen, phosphat- oder ammoniumchloridreichen Ernährung auf die Entwicklung und den Mineralstoffhaushalt wachsender Zwergschweine.