Development of cerebellar malignant astrocytoma at site of a medulloblastoma treated 11 years earlier. Case report.
A child treated for a desmoplastic medulloblastoma of the left cerebellar hemisphere at the age of 10 months developed a malignant astrocytoma in the same site 11 years later. Theories of origin of the second tumor, particularly in relation to concepts of the genesis of medulloblastoma in general, are discussed.
D001254:Astrocytoma / Q000473:pathology*; D002528:Cerebellar Neoplasms / Q000473:pathology*; D002648:Child; D006801:Humans; D008297:Male; D008527:Medulloblastoma / Q000473:pathology*; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D013997:Time Factors