Gastrin secretion in Addison's disease.
Out of a score of patients known as suffering from Addison's disease, tuberculosis was the cause in 7, and their serum fasting gastrin levels were normal, averaging 52 pg/ml. For the 14 remaining cases, with the auto-immune variety of the disease, there were high gastrin levels in 3; in 2 out the 11 others, with values within the normal range, there was total achlorhydria. Could it be that gastrin-secreting cells might occasionally be involved in auto-immune endocrine disorders?
D000224:Addison Disease / Q000209:etiology / Q000276:immunology / Q000503:physiopathology*; D001327:Autoimmune Diseases; D005260:Female; D005755:Gastrins / Q000378:metabolism*; D006801:Humans; D008297:Male
D005755:Gastrins