Enzymatic preparation of the 5'-triphosphates of 2'-deoxytubercidin, 2'-deoxytoyocamycin, and 2'-deoxyformycin and the allosteric effects of these nucleotides on ribonucleotide reductase.
D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D001665:Binding Sites; D003570:Cytidine Triphosphate / Q000378:metabolism; D003854:Deoxyribonucleotides / Q000494:pharmacology*; D005573:Formycins / Q000138:chemical synthesis / Q000494:pharmacology*; D007700:Kinetics; D012263:Ribonucleosides / Q000494:pharmacology*; D012264:Ribonucleotide Reductases / Q000037:antagonists & inhibitors*; D014127:Toyocamycin / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000494:pharmacology*; D014372:Tubercidin / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000494:pharmacology*
D000903:Antibiotics, Antineoplastic; D003854:Deoxyribonucleotides; D005573:Formycins; D012263:Ribonucleosides; D003570:Cytidine Triphosphate; D012264:Ribonucleotide Reductases; D014127:Toyocamycin; D014372:Tubercidin