title: Presence of a pineal nerve (nervus pinealis) in the human fetus: a light and electron microscopical study of the innervation of the pineal gland.
abstract: The presence of a hitherto undiscovered nerve located in the subarachnoidal space just caudal to the pineal organ, connecting this organ and the posterior commissure, was demonstrated by light and electron microscopy in a series of 18 human fetuses. This nerve is believed to be ontogenetically equivalent to the pineal nerve observed in the anuran amphibians. The nerve was present in fetuses with a CRL of 56 mm and had not disappeared in fetuses with a CRL of 169 mm. The gestational age at which this human fetal nerve degenerates could not be determined in this study. In addition to the bilateral conarian nerve a habenulopineal tract and an intrapineal ganglion were observed. The presence of the classical Pastori and Marburg ganglia was confirmed, and a new ganglion lying rostral to the pineal organ was seen too.
mesh_terms: D005260:Female; D005724:Ganglia / Q000033:anatomy & histology; D005865:Gestational Age; D006801:Humans; D008297:Male; D008636:Mesencephalon / Q000033:anatomy & histology; D009412:Nerve Fibers / Q000648:ultrastructure; D009434:Neural Pathways / Q000033:anatomy & histology; D009474:Neurons / Q000648:ultrastructure; D010870:Pineal Gland / Q000033:anatomy & histology / Q000196:embryology*; D011247:Pregnancy; D013788:Thalamus / Q000033:anatomy & histology