Bile acids. OV. 2,2-Dimethoxypropane: an esterifying agent preferred to diazomethane for chenodeoxycholic acid.
Artifacts formed by methylation of chenodeoxycholic acid with diazomethane are identical to the synthetic 3alpha- and 7 alpha-monomethyl ethers of methyl chenodeoxycholate. The extent of formation of these artifacts with time has been studied. No detectable artifacts were found with 2,2-dimethoxypropane as the methylating agent.
D055598:Chemical Phenomena; D002621:Chemistry; D002635:Chenodeoxycholic Acid; D002845:Chromatography; D003978:Diazomethane; D008745:Methylation; D011407:Propane / Q000031:analogs & derivatives*; D020005:Propanols
D020005:Propanols; D002635:Chenodeoxycholic Acid; D003978:Diazomethane; C017240:2,2-dimethoxypropane; D011407:Propane