[Glucose tolerance and insulin sensitivity of rats poisoned with amanita-phalloidines].
The effect Amanita phalloides on glucose tolerance and insuline sensitivity was studied. Amanita phalloides toxins were injected to albino male rats intraperitoneally in a dose of DL50. Amanita phalloides proved to cause disturbance of glucose tolerance, increased tissue glucose utilization, and enhanced the organism insuline sensitivity. The mentioned effects result from a decrease of insuline-inactivating capacity of the liver and from enhanced function of the insuline apparatus of the pancreas.
D000545:Amanita; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D005951:Glucose Tolerance Test; D007328:Insulin; D008297:Male; D009145:Mushroom Poisoning / Q000378:metabolism*; D010590:Phalloidine / Q000506:poisoning; D051381:Rats
D001786:Blood Glucose; D007328:Insulin; D010590:Phalloidine
Tolerantnost' k gliukoze i chuvstvitel'nost' k insulinu u krys, otravlennykh amanita-falloidinami.