title: Reduction of pheniramine toxicity using activated charcoal.
abstract: Pheniramine is efficiently adsorbed by Norit Medicinal Activated Charcoal in vitro. Administration of activated charcoal after pheniramine ingestion in dogs resulted in significantly lower blood levels. Norit or another proven effective activated charcoal would be of value in first-aid treatment of pheniramine poisoning.
mesh_terms: D000818:Animals; D002606:Charcoal / Q000494:pharmacology*; D004285:Dogs; D005260:Female; D007408:Intestinal Absorption / Q000187:drug effects; D008297:Male; D010632:Pheniramine / Q000037:antagonists & inhibitors* / Q000378:metabolism / Q000506:poisoning; D013997:Time Factors
chemical_list: D010632:Pheniramine; D002606:Charcoal