[Conservative therapy of acute ulcer hemorrhage using somatostatin. Pilot study].
Somatostatin (SST) infusion was used to treat severe upper intestinal hemorrhage in 10 patients with peptic ulcer disease. Bleeding ceased in all patients 4-8 h after start of infusion. In one case bleeding recurred when SST infusion was discontinued; SST was given again and the hemorrhage definitively halted. Another patient suffered a recurrence while under SST infusion and had to be operated upon. SST appears to be effective in controlling hemorrhage from peptic ulcer, though further studies are required.
D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006487:Hemostasis; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000188:drug therapy*; D010865:Pilot Projects; D013004:Somatostatin / Q000627:therapeutic use*; D013557:Switzerland
D013004:Somatostatin
Konservative Therapie der akuten Ulkusblutung mit Somatostatin. Pilotstudie.