title: [Residue determinations in milk following application of the fasciolicides rafoxanide and hexachloro-p-xylene].
abstract: The control of Fasciola hepatica in dairy cattle may lead to considerable residue problems in dairying. In the GDR, a hexachloro-p-xylene-based fasciolicide has been approved till recently, and another, rafoxanide-based fasciolicide has been on trial. The investigations have shown that the two active principles are excreted in the milk for a prolonged period, rafoxamide being found more suitable. Their marked lipophil behaviour leads to accumulation in the fat phase and, thus, in high-fat milk products.
mesh_terms: D000818:Animals; D000980:Antiplatyhelmintic Agents / Q000378:metabolism*; D002079:Butter / Q000032:analysis; D002417:Cattle; D003611:Dairy Products / Q000032:analysis; D005210:Fasciola hepatica; D005211:Fascioliasis / Q000188:drug therapy; D005260:Female; D005506:Food Contamination / Q000032:analysis; D005859:Germany, East; D008892:Milk / Q000378:metabolism*; D010573:Pesticide Residues / Q000032:analysis; D011247:Pregnancy; D011888:Rafoxanide / Q000378:metabolism* / Q000627:therapeutic use; D012457:Salicylamides / Q000378:metabolism*; D014992:Xylenes / Q000378:metabolism* / Q000627:therapeutic use
chemical_list: D000980:Antiplatyhelmintic Agents; D010573:Pesticide Residues; D012457:Salicylamides; D014992:Xylenes; D011888:Rafoxanide; D002079:Butter
vernacular_title: Rückstandsuntersuchungen bei Milch nach Anwendung der Fasziolizide Rafoxanid und Hexachlor-p-xylol.