Defective neutrophil chemotaxis corrected by levamisole in Crohn's disease.
In a 26-year-old man with Crohn's disease, evaluation of the neutrophil polymorphonuclear (PMN) function showed marked impairment of chemotaxis, while NBT tests, phagocytosis, random migration and adhesiveness were all normal. PMN chemotaxis was found normal after levamisole therapy.
D000328:Adult; D002633:Chemotaxis / Q000187:drug effects*; D003424:Crohn Disease / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use*; D008297:Male; D009504:Neutrophils / Q000276:immunology
D007978:Levamisole