Method for the rapid estimation of the total body drug clearance and adjustment of dosage regimens in patients during a constant-rate intravenous infusion.
D000818:Animals; D004334:Drug Administration Schedule; D006801:Humans; D007263:Infusions, Parenteral; D008657:Metabolic Clearance Rate; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D011817:Rabbits; D013806:Theophylline / Q000008:administration & dosage / Q000097:blood
D004364:Pharmaceutical Preparations; D013806:Theophylline