[Pathophysiologic mechanisms of depressive states of endogenous or exogenous origin].
A total of 117 patients with depression of a various genesis were studied. The patients with endogenous (circular) depression displayed a correlation between the EEG, vascular and vegetative tonus, catecholamine excretion (especially noradrenaline) and peculiarities of the clinical picture. In patients with somatogenic depression a correlation between the studied indices of a functional state of an organism is not present. Psychogenic depression is characterized by a domination of desynchronized activity of low volts in the EEG and the existence of expressed sympathicotony of the peripheral vegetative system, while statistically significant shifts of the vascular tonus and catecholamine excreation are absent.
D000328:Adult; D001341:Autonomic Nervous System / Q000503:physiopathology*; D001679:Biogenic Amines / Q000032:analysis*; D001921:Brain / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000503:physiopathology; D002746:Chlorpromazine; D003863:Depression / Q000097:blood / Q000503:physiopathology* / Q000652:urine; D004295:Dihydroxyphenylalanine / Q000652:urine; D004298:Dopamine / Q000652:urine; D004569:Electroencephalography; D004837:Epinephrine / Q000652:urine; D005260:Female; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000652:urine; D009638:Norepinephrine / Q000652:urine; D012701:Serotonin / Q000097:blood; D014655:Vascular Resistance
D001679:Biogenic Amines; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D004295:Dihydroxyphenylalanine; D002746:Chlorpromazine; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine
Patofiziologicheskie mekhanizmy depressivnykh sostoianiĭ éndogennogo i ékzogennogo geneza.