title: [Studies on the long acting neuroleptic agent flupenthixol decanoate--a review (author's transl)].
abstract: The development of long acting neuroleptic agents is considered as important progress in the treatment of schizophrenic psychoses. An outline of pharmacological and clinical results with flupenthixol decanoate is given. Special attention is paid to pharmacokinetics, the methods for determining plasma concentration, to the profile of action and duration of action, to other dosage as well as to safety. Importance is also placed on the possible use for prophylaxis of affective psychoses.
mesh_terms: D003692:Delayed-Action Preparations; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004409:Dyskinesia, Drug-Induced / Q000209:etiology; D005475:Flupenthixol / Q000009:adverse effects / Q000097:blood / Q000627:therapeutic use*; D006801:Humans; D011618:Psychotic Disorders / Q000188:drug therapy; D012559:Schizophrenia / Q000097:blood / Q000188:drug therapy; D013892:Thioxanthenes / Q000627:therapeutic use*
chemical_list: D003692:Delayed-Action Preparations; D013892:Thioxanthenes; D005475:Flupenthixol
vernacular_title: Erfahrungen mit dem Depotneuroleptikum Flupentixoldekanoat--Eine Ubersicht.