Essential hypernatremia.
Described is a patient who presented with hypernatremia in the absence of dehydration. Further investigation revealed a tumor in the hypothalamic area, and evidence of anterior pituitary hypofunction. Water loading did not correct hypernatremia, and the results of the water-loading test suggested that hypernatremia had resulted from an elevated "osmotic set point" for the release of antidiuretic hormone, ie, "essential hypernatremia."
D000293:Adolescent; D001932:Brain Neoplasms / Q000150:complications / Q000503:physiopathology; D005260:Female; D006801:Humans; D006955:Hypernatremia / Q000175:diagnosis / Q000209:etiology*; D007031:Hypothalamus / Q000503:physiopathology; D009994:Osmolar Concentration; D014667:Vasopressins / Q000378:metabolism; D014867:Water
D014867:Water; D014667:Vasopressins