[Biological effect of lipid fractions of Actinomycetes].
Biological activity of lipid fractions of actinomycetes was examined on microorganisms and laboratory animals. The anabolic effect of the acetone fraction of Actinomyces aurigineus 2377 (on Wistar female rats), anabolic effect of sterols of Actinomyces griseus 15 (on chicks), and the high growth stimulating effect (up to 40-60%) of sterols of Actinomyces canosus 89 (on rats) were noted. The estrogenic effect of sterols of Act. griseus 15, Act. griseus 20 and Act. albodenitrificans 13a on the sex system was shown. The antimicrobial properties of lipid fractions differed in their selectivity with respect to the test organisms and depended also on the actinomycete species and cultivation conditions.
D000190:Actinomyces; D000818:Animals; D001681:Biological Assay; D002645:Chickens; D005260:Female; D008055:Lipids / Q000494:pharmacology*; D051381:Rats; D013045:Species Specificity; D013261:Sterols / Q000494:pharmacology
D008055:Lipids; D013261:Sterols
Biologicheskoe deĭstvie lipidnykh fraktsiĭ aktinomitsetov.