title: Superior vena caval syndrome.
abstract: The two cases of the superior vena caval syndrome described illustrate the problem of making a diagnosis and of determining the etiology of this syndrome. The cutaneous manifestations were typical of the syndrome and included the sudden onset of facial and upper extremity edema, erythema, and telangiectasia. The causes of the syndrome cannot be recognized from the clinical presentation. In one of our cases, the cause was only determined at autopsy and proved to be an unusual benign cause, idiopathic thrombosis, masquerading as a malignant tumor; the other case was caused by an actual malignancy. The manifestations of the syndrome should alert the physician to determine its cause in order that appropriate therapy may be instituted as rapidly as possible.
mesh_terms: D004487:Edema / Q000150:complications / Q000209:etiology; D004890:Erythema / Q000150:complications / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000150:complications*; D013577:Syndrome; D013684:Telangiectasis / Q000150:complications / Q000209:etiology; D014652:Vascular Diseases / Q000150:complications / Q000209:etiology; D014683:Vena Cava, Superior