Fluorometric determination of metaraminol bitartrate injection.
A fluorescence assay for metaraminol bitartrate injection has been developed which uses o-phthalaldehyde as a fluorogenic reagent, and dose not require prior isolation of metaraminol. It is 50 times more sensitive than the USP assay. Six analyses of 2 vials of the same lot of metaraminol bitartrate injection gave 96 +/- 0.4% of label declaration.
D004304:Dosage Forms; D007267:Injections; D008680:Metaraminol / Q000032:analysis*; D013050:Spectrometry, Fluorescence / Q000379:methods; D013644:Tartrates / Q000032:analysis
D004304:Dosage Forms; D013644:Tartrates; D008680:Metaraminol