[Role of vascular thermoreceptors in the mechanism of cold tremor inhibition by oxotremorine, seduxen and phentolamine].
Intravenous infusion of oxotremorine, seduxene, and phentolamine to cats not only decreased the cold-induced tremor, but also reduced the subcutaneous vein receptor impulses. Diminished activity of the vascular thermoreceptors served as an additional component in the mechanisms of the inhibitory effect of oxotremorine and seduxene on cold tremor. Reduction of the thermoreceptors activity after phentolamine administration is primary, and may be considered as the leading factor in the cold tremor inhibition.
D000818:Animals; D001808:Blood Vessels / Q000187:drug effects*; D002415:Cats; D003864:Depression, Chemical; D003975:Diazepam / Q000494:pharmacology*; D009132:Muscles / Q000098:blood supply; D010095:Oxotremorine / Q000494:pharmacology*; D010646:Phentolamine / Q000494:pharmacology*; D012768:Shivering / Q000187:drug effects*; D012867:Skin / Q000098:blood supply; D012881:Skin Temperature / Q000187:drug effects; D013823:Thermoreceptors / Q000187:drug effects*
D010095:Oxotremorine; D003975:Diazepam; D010646:Phentolamine
Rol' sosudistykh termoretseptorov v mekhanizme ugneteniia kholodovogo tremora oksotremorinom, seduksenom i fentolaminom.