Formylhydrazine carcinogenesis in mice.
Administration of 0.125% formylhydrazine in drinking water to 6-week-old randomly bred Swiss albino mice for life, induced lung tumours. Compared to untreated controls, the lung-tumour incidence rose from 15 to 94% in the females and from 22 to 100% in the males. The treatment had no detectable tumorigenic effect in other organs.
D000230:Adenocarcinoma / Q000139:chemically induced; D000236:Adenoma / Q000139:chemically induced; D000818:Animals; D005260:Female; D006834:Hydrazines / Q000633:toxicity*; D008175:Lung Neoplasms / Q000139:chemically induced* / Q000401:mortality; D008297:Male; D051379:Mice; D009374:Neoplasms, Experimental / Q000139:chemically induced
D006834:Hydrazines; C017327:formylhydrazine