[Longitudinal study of 18 cases of prolactin adenoma. Therapeutic results (author's transl)].
Complete endocrinological studies were made before and after surgery in 18 cases of prolactin adenoma (2 giant adenomas and 16 macro-adenomas). Certain points are stressed: the frequency of the haemorrhagic nature of the adenoma in 4 cases, including 1 case of spontaneous necrosis; the great variability in dynamic responses to the TRH stimulation test or inhibition by I-Dopa; the persistence in 14 cases out of 16 of postoperative hyperproclactinaemia, requiring the prescription of 5 to 10 mg/day of bromocriptine, rarely more; the disappearance of total impotence in two male cases as a result of the latter drug, whilst testerone and dihydrotestosterone levels were normal before the beginning of medical treatment.
D000236:Adenoma / Q000378:metabolism* / Q000628:therapy; D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007016:Hypophysectomy; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000378:metabolism* / Q000628:therapy; D011388:Prolactin / Q000378:metabolism*
D001971:Bromocriptine; D011388:Prolactin
Adénomes à prolactine: résultats thérapeutiques. 18 observations.