title: Suicidal inactivation of cytochrome P-450. Formation of a heme-substrate covalent adduct.
mesh_terms: D000081:Acetamides; D000502:Allylisopropylacetamide; D000818:Animals; D001665:Binding Sites; D065607:Cytochrome P-450 Enzyme Inhibitors; D006418:Heme; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology; D011485:Protein Binding; D051381:Rats; D013053:Spectrophotometry
chemical_list: D000081:Acetamides; D065607:Cytochrome P-450 Enzyme Inhibitors; D000502:Allylisopropylacetamide; D006418:Heme; D010634:Phenobarbital