The development of melanoblasts from leg bud mesenchyme grown in the celom of chick embryos.
Presence of extra-epidermal melanoblasts in the messenchyme of leg bud have been acertained. Small pieces of 0.2 mm3 of isolated mesoderm of outer and inner core, from leg bud of 5 day Silver Campine, grafted into celom of 3 day White Leghorn gave positive results. The viability and migratory capacity of these cells have been practically examined. The migration of pigment cells into the hind limb musculature; differentiation of melanoblasts in different tissue environments and the behaviour of grafted melanoblasts in the host body is discussed.
D000818:Animals; D002642:Chick Embryo / Q000254:growth & development*; D006614:Hindlimb; D008544:Melanocytes; D008648:Mesoderm / Q000637:transplantation