title: Electrophoretic bimorphism of serum albumin in the presence of indocyanine green.
abstract: The presence of indocyanine green during extended traditional electrophoresis and immunoelectrophoresis of serum is associated with bimorphism of albumin. This occurs over a range of dye--albumin molar ratios an order or more greater than was obtained in similar phenomena described previously. The bimorphism seems not to be dose dependent beyond a certain point, and the two albumins so separated show tinctorial differences. The phenomenon has been observed to apparently the same degree in all normal sera tested, and may represent a means of distinguishing ligand-loaded and ligand-light serum albumin.
mesh_terms: D001797:Blood Protein Electrophoresis; D005260:Female; D006801:Humans; D007122:Immunoelectrophoresis; D007208:Indocyanine Green; D008024:Ligands / Q000097:blood; D008297:Male; D012709:Serum Albumin / Q000032:analysis*
chemical_list: D008024:Ligands; D012709:Serum Albumin; D007208:Indocyanine Green