[Adaptation to the Centrifichem of the estimation of blood sugar according to Trinder's method. Kinetic study of the main drug interferences (author's transl)].
The method of estimation of glucose described by Trinder was adapted to analysis by centrifugation (Centrifichem). A kinetic study of drug interferences (ascorbic acid, gentisic acid, levodopa, alphamethyldopa) was carried out. The choice of parameters of the method was justified by an increased specificity of the reaction and by an extremely narrow correlation with the technics using hexokinase (r = 0.994) and glucose dehydrogenase (r = 0.996).
D001205:Ascorbic Acid / Q000494:pharmacology; D001786:Blood Glucose / Q000032:analysis*; D002498:Centrifugation / Q000379:methods; D005841:Gentisates / Q000494:pharmacology; D007700:Kinetics; D007980:Levodopa / Q000494:pharmacology; D008750:Methyldopa / Q000494:pharmacology
D001786:Blood Glucose; D005841:Gentisates; D007980:Levodopa; D008750:Methyldopa; D001205:Ascorbic Acid
Adaptation au Centrifichem du dosage de la glycémie selon Trinder. Etude cinétique des principales interférences médicamenteuses.