[Effect of genotype on the angiotensin-forming system of plasma and the hypothalamus].
It is shown that hypothalamic renin-like enzyme of mice (lines C57B1/6 and BALB/c) consists of two forms differing from one another in their molecular weight. The allele AY determines the absence of the heavy form of renin-like hypothalamic enzyme (RLHE) and a relatively low level of activity of the blood plasma renin in intact animals. The heavy form of RLHE disappears in mice in case of a considerable dehydration.
D000809:Angiotensins / Q000096:biosynthesis / Q000097:blood / Q000235:genetics*; D000818:Animals; D005796:Genes; D005838:Genotype; D007031:Hypothalamus / Q000378:metabolism*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D013045:Species Specificity
D000809:Angiotensins
O vliianii genotipa na angiotenzinobrazuiushchie sistemy plazmy i gipotalamusa.