Methionine toxicity in chicks and poults.
In feeding experiments with poults, 2% DL-methionine caused a marked growth depression which could be alleviated by the addition of glycine. Homocystine at an equimolar level depressed growth to a lesser degree than methionine, and this growth depression could be alleviated by glycine. Betaine could alleviate the growth depression of homocystine but not that of methionine. Methionine-fed poults developed a cervical paralysis similar to that of a folic acid deficiency, but the addition of this vitamin at several times the requirement was ineffective in counteracting the toxicity of methionine in either chicks or poults.
D000818:Animals; D001622:Betaine / Q000627:therapeutic use; D001848:Bone Diseases, Developmental / Q000139:chemically induced / Q000517:prevention & control / Q000662:veterinary; D002645:Chickens; D005492:Folic Acid / Q000627:therapeutic use; D005998:Glycine / Q000627:therapeutic use; D006711:Homocystine / Q000633:toxicity; D008297:Male; D008715:Methionine / Q000633:toxicity*; D010243:Paralysis / Q000139:chemically induced / Q000517:prevention & control / Q000662:veterinary; D011201:Poultry Diseases / Q000139:chemically induced* / Q000517:prevention & control; D014422:Turkeys
D001622:Betaine; D006711:Homocystine; D005492:Folic Acid; D008715:Methionine; D005998:Glycine