Solasodine stability under conditions of saponin hydrolysis.
The extent of formation of solasodiene from solasodine upon treatment with hydrochloric acid under various conditions was determined. The diene formed was assayed by using the characteristic extinction at 236 nm. Diene formation was effected by the acid concentration and the boiling point of the solvent used. Optimal conditions for the hydrolysis of solasodine glycosides are suggested.
D002855:Chromatography, Thin Layer; D004355:Drug Stability; D006868:Hydrolysis; D009994:Osmolar Concentration; D012991:Solanaceous Alkaloids / Q000032:analysis; D012997:Solvents; D013056:Spectrophotometry, Ultraviolet; D013816:Thermodynamics
D012991:Solanaceous Alkaloids; D012997:Solvents; C012037:solasodine