Time course of protection from audiogenic seizures by glucose and insulin in audiogenically primed C57BL/6J mice.
Glucose and insulin injections both decrease seizure susceptibility in C57BL/6J mice subjected to audiogenic priming at 16 days of age and tested at 21 days of age. These data support an hypothesis of defect in immediately available energy reserves in brains of audiogenic seizure prone mice.
D000161:Acoustic Stimulation; D000818:Animals; D000927:Anticonvulsants; D001786:Blood Glucose / Q000378:metabolism; D005947:Glucose / Q000494:pharmacology*; D007328:Insulin / Q000494:pharmacology*; D051379:Mice; D008810:Mice, Inbred C57BL; D012640:Seizures / Q000503:physiopathology*; D013997:Time Factors
D000927:Anticonvulsants; D001786:Blood Glucose; D007328:Insulin; D005947:Glucose