[Effect of somatostatin on the endogenous release of secretin and pancreatic polypeptide in the dog].
In dogs with chronic duodenal and gastric fistula the effect of somatostatin (SST) on the endogenous release of secretin and pancretic polypeptide (PP) was investigated. The release of secretin following intraduodenal acid administration was significantly reduced by SST. While PP increased significantly after a test meal, its release was completely suppressed by SST.
D000818:Animals; D004285:Dogs / Q000502:physiology; D010179:Pancreas / Q000187:drug effects; D010187:Pancreatic Hormones / Q000378:metabolism*; D010455:Peptides / Q000378:metabolism*; D012633:Secretin / Q000378:metabolism*; D013004:Somatostatin / Q000494:pharmacology*
D010187:Pancreatic Hormones; D010455:Peptides; D012633:Secretin; D013004:Somatostatin
Der Einfluss von Somatostatin auf die endogene Freisetzung von Sekretin und Pancreatic Polypeptide beim Hund.