[Monoamine oxidation in the mitochondrial fraction of bovine kidney catalyzed by monoamine oxidase type B].
Oxidative deamination of tyramine, serotonin and benzyl amine in bovine kidney mitochondria was inhibited by low concentrations of deprenil (but not clorgylline). These data and the patterns of the plots of residual enzymatic activity against concentration of the inhibitors as well as the "mixed substrates" experiments suggest occurrence in bovine kidney mitochondria of monoamine oxidase of the B type only, which has to be considered in studies on the nature of monoamine oxidases using bovine kidney mitochondria as a rich source of monoamine oxidase activity.
D000818:Animals; D001596:Benzylamines / Q000378:metabolism; D002384:Catalysis; D002417:Cattle; D003010:Clorgyline / Q000494:pharmacology; D066298:In Vitro Techniques; D007527:Isoenzymes / Q000378:metabolism*; D007668:Kidney / Q000201:enzymology* / Q000648:ultrastructure; D008928:Mitochondria / Q000201:enzymology; D008995:Monoamine Oxidase / Q000378:metabolism*; D010627:Phenethylamines / Q000378:metabolism / Q000494:pharmacology; D012701:Serotonin / Q000378:metabolism; D014439:Tyramine / Q000378:metabolism
D001596:Benzylamines; D007527:Isoenzymes; D010627:Phenethylamines; D012701:Serotonin; D008995:Monoamine Oxidase; D003010:Clorgyline; D014439:Tyramine
Okislenie monoaminov v mitokhondrial'noĭ fraktsii pochek byka, kataliziruemoe monoaminoksidazoĭ tipa B.