[Mechanism of formation of epileptic activity complexes in the cerebral cortex under the influence of a determinant focus].
It was shown in the experiments on cats anesthetized by nembutal that by forming a hyperactive focus with a high level of excitation in the temporal cortex and a number of foci with a less higher level of the excitation in other parts of neocortex, it is possible to create a functional complex, working in a single routine, determined by the activity of hyperactive focus. The latter plays a role of a determinant structure. The inhibition of the determinant focus results in the disturbance of the epileptic complex. Focus nature has no sufficient importance in the realization of the following interrelations: both the determinant focus and dependent foci may be created by means of strychnin and penicillin, disturbing different forms of the inhibition. The results of our investigations evidence a common conception on the role of determinant structures in the activity of the nervous system.
D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000503:physiopathology*; D004594:Electrophysiology; D010406:Penicillins; D012640:Seizures / Q000139:chemically induced / Q000503:physiopathology*; D013331:Strychnine; D013702:Temporal Lobe / Q000503:physiopathology
D010406:Penicillins; D013331:Strychnine
K mekhanizmu obrazovaniia kompleksov épilepticheskoĭ aktivnosti v kore golovnogo mozga pod vliianiem determinantnogo ochaga.