[Hypothermic circulatory arrest after total blood exchange in dogs (author's transl)].
Total body washout (hct less than 1%) in hypothermia was performed in 31 dogs using either a crystalloidal or a colloidal perfusate. Blood exchange and cooling was achieved by means of partial bypass and heat exchanger. Short lasting blood exchange for crystalloids without cardiac arrest resulted in 66% survival of the animals. When in addition circulatory arrest was established for 30 min at 14 degrees C oesophageal temperature blood exchange for crystalloids was not tolerated. All four animals of this group died within 19 hours presenting massive interstitial edema. Replacement of the crystalloidal perfusate by a colloidal solution (2.5 g% Dextran 60 at Ringer's Lactate) and establishing circulatory for 30 or 60 min resulted in survival rates of 71% and 50% respectively. The use of the colloidal perfusate effectively prevented edema formation. Death could not be correlated with the parameters controlled.
D000818:Animals; D003102:Colloids / Q000494:pharmacology*; D004285:Dogs; D004487:Edema / Q000517:prevention & control*; D005078:Exchange Transfusion, Whole Blood / Q000009:adverse effects*; D005112:Extracorporeal Circulation; D005260:Female; D007035:Hypothermia; D008297:Male; D011379:Prognosis
D003102:Colloids
Hypothermer Kreislaufstillstand nach totalem Blutaustausch beim Hund.