title: Pharmacokinetics of 1-desamino-8-D-arginine vasopressin (DDAVP) in patients with central diabetes insipidus.
abstract: The pharmacokinetic parameters and biological duration of action of DDAVP were measured in five patients with central diabetes insipidus of differing severity. Plasma half-life correlated significantly with the duration of action (r = 0.89, P less than 0.05), 0ut there was no correlation between the severity of diabetes insipidus and either plasma half-life or duration of action of DDAVP.
mesh_terms: D000328:Adult; D000368:Aged; D001127:Arginine Vasopressin / Q000378:metabolism*; D003894:Deamino Arginine Vasopressin / Q000097:blood / Q000378:metabolism*; D003919:Diabetes Insipidus / Q000378:metabolism*; D005260:Female; D006207:Half-Life; D006801:Humans; D007700:Kinetics; D008297:Male; D008657:Metabolic Clearance Rate
chemical_list: D001127:Arginine Vasopressin; D003894:Deamino Arginine Vasopressin