The effects of mesterolone on the male accessory sex organs, on spermiogram, plasma testosterone and FSH.
42 subfertile male ambulatory patients were treated with Proviron. Moderate oligoastheno-teratozoospermia was the most common injury in sperm analysis. The treatment did not change the amount of plasma FSH, testosterone or prostate phosphatase. Acid phosphatase and citric acid of semen showed an increased activity with mesterolone treatment. The amount of fructose decreased, it is probably due to the increased number of spermatozoa, which need more fructose for their metabolism respectively. The sperm of 93% of the patients improved or stayed unchanged. 30% of the patients developed normozoospermia. 6 pregnancies were achieved.
D000135:Acid Phosphatase / Q000378:metabolism; D000328:Adult; D002951:Citrates / Q000378:metabolism; D013196:Dihydrotestosterone / Q000031:analogs & derivatives*; D005640:Follicle Stimulating Hormone / Q000097:blood*; D005632:Fructose / Q000378:metabolism; D006801:Humans; D008297:Male; D008655:Mesterolone / Q000494:pharmacology*; D011467:Prostate / Q000187:drug effects* / Q000201:enzymology; D012661:Semen / Q000378:metabolism; D012669:Seminal Vesicles / Q000187:drug effects* / Q000378:metabolism; D013094:Spermatozoa / Q000187:drug effects; D013739:Testosterone / Q000097:blood*; D013997:Time Factors
D002951:Citrates; D013196:Dihydrotestosterone; D008655:Mesterolone; D005632:Fructose; D013739:Testosterone; D005640:Follicle Stimulating Hormone; D000135:Acid Phosphatase