title: Effect of methylmercury on some constituents of serum and urine.
abstract: To evaluate some of the early effects of methymercury chloride (MMC) male rats were given 10, 20 or 30 mg MMC/kg intraperitoneally. Urine was analysed for vanilmandelic acid (VMA), leucine aminopeptidase (LAP), alkaline phosphatase (AP), and creatinine, blood for glucose-6-phosphatase (G-6-P) and glucose, serum for glutamate-oxalate-transaminase (GOT) and urea. Except for LAP and AP excretion there is no effect of MMC on the parameters investigated. However, the effects on these 2 renal enzymes are to variable to permit their use as a test for MMC toxicity.
mesh_terms: D000469:Alkaline Phosphatase / Q000652:urine; D000818:Animals; D003404:Creatinine / Q000652:urine; D007931:Leucyl Aminopeptidase / Q000652:urine; D008297:Male; D008767:Methylmercury Compounds / Q000633:toxicity*; D051381:Rats; D014642:Vanilmandelic Acid / Q000652:urine
chemical_list: D008767:Methylmercury Compounds; D014642:Vanilmandelic Acid; D003404:Creatinine; D000469:Alkaline Phosphatase; D007931:Leucyl Aminopeptidase