title: EEG-changes during general anaesthesia with enflurane (Efrane) in comparison with ether.
abstract: The effects of enflurane (efrane) and ether on the cerebral functions were studied by EEG on two similar groups of adult patients. For basic comparison a depth of anaesthesia was chosen which permitted abdominal surgery without the need to administer muscular relaxants. At this level of anaesthesia the typical EEG-changes of paroxysmal type which have been described with enflurane were seen only occasionally. If, however, the depth of anaesthesia was further increased, such EEG-changes indicating increased cerebral excitability were seen more often under enflurane and also appeared under ether anaesthesia. No seizure activity was recorded.
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D001921:Brain / Q000378:metabolism; D004569:Electroencephalography; D004737:Enflurane / Q000494:pharmacology; D004986:Ether / Q000494:pharmacology; D005019:Ethyl Ethers / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D008738:Methyl Ethers / Q000494:pharmacology; D008875:Middle Aged; D010101:Oxygen Consumption / Q000187:drug effects
chemical_list: D005019:Ethyl Ethers; D008738:Methyl Ethers; D004986:Ether; D004737:Enflurane