title: Ghost infantile vertebrae and hemipelves within adult skeleton from thorotrast administration in childhood.
abstract: In 2 adults who had received thorotrast intravenously at ages 2 and 3 years, respectively, radiopaque outlines of their infantile vertebrae were seen in the adult vertebrae. Similar "ghosts" of the hemipelves were present in the pelvis of 1 patient. Autopsy findings and autoradiographs in 1 patient strongly suggest that persisting thorotrast deposits in the infantile vertebrae and pelvis have produced a chronic radiation osteitis and dense thickened bone trabeculae, which are more radiopaque than the surrounding adult bone.
mesh_terms: D000328:Adult; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D010000:Osteitis / Q000000981:diagnostic imaging / Q000209:etiology*; D010384:Pelvic Bones / Q000000981:diagnostic imaging / Q000528:radiation effects; D011832:Radiation Injuries; D011859:Radiography; D013122:Spinal Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D013131:Spine / Q000000981:diagnostic imaging / Q000528:radiation effects; D013911:Thorium Dioxide / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D013911:Thorium Dioxide