Effect of methylmercury on some constituents of serum and urine.
To evaluate some of the early effects of methymercury chloride (MMC) male rats were given 10, 20 or 30 mg MMC/kg intraperitoneally. Urine was analysed for vanilmandelic acid (VMA), leucine aminopeptidase (LAP), alkaline phosphatase (AP), and creatinine, blood for glucose-6-phosphatase (G-6-P) and glucose, serum for glutamate-oxalate-transaminase (GOT) and urea. Except for LAP and AP excretion there is no effect of MMC on the parameters investigated. However, the effects on these 2 renal enzymes are to variable to permit their use as a test for MMC toxicity.
D000469:Alkaline Phosphatase / Q000652:urine; D000818:Animals; D003404:Creatinine / Q000652:urine; D007931:Leucyl Aminopeptidase / Q000652:urine; D008297:Male; D008767:Methylmercury Compounds / Q000633:toxicity*; D051381:Rats; D014642:Vanilmandelic Acid / Q000652:urine
D008767:Methylmercury Compounds; D014642:Vanilmandelic Acid; D003404:Creatinine; D000469:Alkaline Phosphatase; D007931:Leucyl Aminopeptidase