Metabolism of interferon (facts and fancy).
Although the knowledge of the interferon metabolism is still incomplete, two organs are emerging as elective sites. The kidney and probably the liver may share a major role but only future research will define quantitatively their importance. Many aspects of interferon activity upon cellular processes and its possible function as a 'chalone-type' substance are reviewed.
D000818:Animals; D006207:Half-Life; D006801:Humans; D007372:Interferons / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism*; D007678:Kidney Glomerulus / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D011817:Rabbits; D011955:Receptors, Drug / Q000378:metabolism; D012795:Sialoglycoproteins / Q000378:metabolism
D011955:Receptors, Drug; D012795:Sialoglycoproteins; D007372:Interferons