[Effect of carbon dioxide on the methylotrophic metabolism of Candida boidinii].
The activity of enzymes involved in carbon metabolism of Candida boidinii KDI was compared on media containing methanol with bicarbonate and without it. The presence of carbon dioxide stimulated the activity of methanol oxidase, formaldehyde dehydrogenase, hexulose phosphate synthase and particularly carboxylases of pyruvate and phosphoenol pyruvate. At the same time, the activity of formate dehydrogenase, citrate synthase and isocitrate lyase decreased. Therefore, carbon dioxide produces a significant effect on methylotrophic metabolism of Candida boidinii KDI and is actively involved in biosynthetic processes.
D001639:Bicarbonates / Q000378:metabolism; D002175:Candida / Q000187:drug effects* / Q000378:metabolism; D002245:Carbon Dioxide / Q000494:pharmacology*; D003470:Culture Media; D004789:Enzyme Activation / Q000187:drug effects; D000432:Methanol / Q000378:metabolism*
D001639:Bicarbonates; D003470:Culture Media; D002245:Carbon Dioxide; D000432:Methanol
Vliianie uglekisloty na metilotrofnyĭ metabolizm Candida boidinii.