[Use of biological methods in the testing of extracts of plastics (preliminary report)].
In the first part of the paper the problem of toxicological testing of medical plastics is discussed. Particularly attention was given to the biological testing of extracts of plastics. The results of own investigations on the toxicological testing of extracts in water for injection of three types of polyester vascular prostheses, two types of technical rubber and one type of silicon caouthouc are presented. The author presents a proposal of a new testing method for the toxicological evaluation of extracts in water of medical grade plastics utilizing diluted fresh bull's sperm. The results of the preliminary investigations on different materials proved the bull's spermatozoons to be sensitive to even small qualities of toxic substances composed in various medical grade plastic fabrics. In the author's estimation, there is a good reason to ascertain, that the presented method will be a new biololgical test destined to the preliminary evaluation and the current check-up of plastic medical materials.
D000818:Animals; D001807:Blood Vessel Prosthesis / Q000592:standards*; D002417:Cattle; D008297:Male; D010969:Plastics / Q000592:standards* / Q000633:toxicity; D013094:Spermatozoa / Q000187:drug effects*
D010969:Plastics
Badanie wyciagów z tworzyw sztucznych metodami biologicznymi. Doniesienie tymczasowe.