Prolonged, transapical left ventricular bypass (TALVB) in sheep and man.
Transapical left ventricular bypass has been demonstrated in normal sheep and one lamb. Recently, TALVB was applied in 3 clinical cases of cardiac failure, with recovery of myocardial function in one patient after 9 days of bypass (6 days total TALVB). These studies suggest that LV apical cannula-roller pump bypass with low dose heparin anticoagulation and secondary surgery to remove the cannula may salvage some patients now dying of temporary cardiac failure.
D000328:Adult; D000818:Animals; D001772:Blood Cell Count; D001792:Blood Platelets; D002302:Cardiac Output; D002404:Catheterization; D006333:Heart Failure / Q000628:therapy; D006352:Heart Ventricles; D006354:Heart, Artificial / Q000295:instrumentation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012756:Sheep; D013997:Time Factors