title: Diffuse cerebral sclerosis, melanoderma and adrenal insufficiency (adreno-leukodystrophy).
abstract: Two cases of adrenoleukodystrophy are described. The pathological picture was consistent with earlier observations about the disease with the difference that the brain tissue revealed material which stained metachromatically with toluidine blue and was insoluble in fat solvents.
mesh_terms: D000307:Adrenal Gland Diseases / Q000473:pathology; D000311:Adrenal Glands / Q000473:pathology; D000309:Adrenal Insufficiency / Q000473:pathology; D000328:Adult; D001921:Brain / Q000473:pathology; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000473:pathology; D012867:Skin / Q000473:pathology; D013577:Syndrome