Lymphangioma circumscriptum following radical mastectomy and radiation therapy.
Lymphangioma circumscriptum, a rare long-term complication of chronic lymphedema, has been described only twice following radical mastectomy. The case discussed in this report developed 25 years after radical mastectomy and radiation therapy. Both this condition and lymphangiosarcoma, its malignant counterpart, may arise in lymphedematous extremities regardless of the etiology of the lymphatic obstruction.
D000368:Aged; D001365:Axilla; D001943:Breast Neoplasms / Q000628:therapy*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects; D008202:Lymphangioma / Q000209:etiology* / Q000473:pathology; D008209:Lymphedema / Q000150:complications / Q000209:etiology; D008408:Mastectomy / Q000009:adverse effects* / Q000379:methods; D009378:Neoplasms, Multiple Primary / Q000209:etiology*; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D013997:Time Factors