title: The amino-acid sequence of S-100 protein (PAP I-b protein) and its relation to the calcium-binding proteins.
abstract: The amino acid sequence of a brain-specific protein, S-100, has been determined by the analysis of four cyanogen bromide peptides and fourteen tryptic peptides derived from the protein. The protein chain consists of 91 amino acid residues and has a molecular weight of 10507. The sequence shows regions of stong clustering of hydrophobic, basic and acidic amino acids, with an apparent calcium-binding site in the acidic cluster.
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002118:Calcium; D002352:Carrier Proteins; D002417:Cattle; D009419:Nerve Tissue Proteins; D010446:Peptide Fragments / Q000032:analysis; D009418:S100 Proteins
chemical_list: D000596:Amino Acids; D002352:Carrier Proteins; D009419:Nerve Tissue Proteins; D010446:Peptide Fragments; D009418:S100 Proteins; D002118:Calcium