Effects of FSH and LH administration on the testes and seminal vesicles.
Weight increases in the testes of pre-pubertal rodents when FSH was administered were revealed by histological observations to be a result of seminiferous tubule lengthening. LH administration effected a sex accessory gland weight increase (seminal vesicles) but there were no apparent testicular effects. The serum androgen level, in response to increased LH administration, showed a continuous decrease in concentration although there was a significant seminal vesicle weight increase. The evidence presented in this paper leads us to postulate that LH has a sensitizing effect on androgen dependent tissues in the pre-pubertal rodent.
D000367:Age Factors; D000728:Androgens / Q000097:blood; D000818:Animals; D005640:Follicle Stimulating Hormone / Q000494:pharmacology*; D007986:Luteinizing Hormone / Q000494:pharmacology*; D008297:Male; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D012669:Seminal Vesicles / Q000187:drug effects*; D013737:Testis / Q000187:drug effects*
D000728:Androgens; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone