title: Oral methoxsalen photochemotherapy of recalcitrant dermatoses of the palms and soles.
abstract: PUVA therapy successfully cleared various dermatoses mainly confined to the palms and soles in 18 of 20 patients treated. The conditions treated were: plaque-type psoriasis, pustular psoriasis, endogenous eczema and persistent palmoplantar pustulosis. Seventeen patients were treated in a controlled study of PUVA therapy versus no treatment at all and in 16 of these patients the disease was cleared in the PUVA-treated areas while the untreated areas remained unchanged or deteriorated. Twelve of the 18 patients were maintained in a clear state by continued maintenance PUVA treatment over 6--31 months while 3 patients had a spontaneous remission and are free of disease off all treatment.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004485:Eczema / Q000188:drug therapy; D005260:Female; D005533:Foot Dermatoses / Q000188:drug therapy*; D006229:Hand Dermatoses / Q000188:drug therapy*; D006801:Humans; D008730:Methoxsalen / Q000627:therapeutic use; D008875:Middle Aged; D010777:Photochemistry; D011565:Psoriasis / Q000188:drug therapy
chemical_list: D008730:Methoxsalen