title: Physiological implications of microbial digestion in the large intestine of mammals: relation to dietary factors.
abstract: The rate of digesta marker passage through the large intestine of the dog, pig, and pony correlated with the relative length and degree of sacculation of the colon. Volatile fatty acids (VFA), the end products of microbial digestion of all forms of carbohydrate, were the major anions present in large intestinal contents of all three species. Total VFA concentration was little affected by the feeding of high-versus low-fiber diets. VFA were rapidly transported across colonic mucosa of all three species. Results of comparative studies indicate that production and absorption of VFA are important to the nutrition of some mammals and to the normal secretory and absorptive functions of the large intestine of most mammals.
mesh_terms: D000818:Animals; D002482:Cellulose; D004043:Dietary Fiber; D004044:Dietary Proteins; D004063:Digestion; D004285:Dogs; D005232:Fatty Acids, Volatile / Q000378:metabolism; D005769:Gastrointestinal Motility; D007408:Intestinal Absorption; D007419:Intestinal Secretions; D007420:Intestine, Large / Q000382:microbiology*; D013552:Swine
chemical_list: D004043:Dietary Fiber; D004044:Dietary Proteins; D005232:Fatty Acids, Volatile; D002482:Cellulose