title: [Experiences with Refobacin-Palacos with regard to deep late infections following hip-joint endoprosthesis surgery. A 4-years' study (author's transl)].
abstract: 667 TEP operations were performed in our hospital from 1970 to 1973. Two groups of patients were treated either with Palacos-R without addition of antibiotics (n = 336) or with Refobacin-Palacos (n = 331). Both groups received a combined postoperative systemic antibiotic infection prophylaxis. The authors' own subsequent investigations, completion of patient questionnaires and--in case of subjective complaints--medical questionnaires, were sufficient to follow up all patients, with the exception of two, over a period of 5--4 or 4--3 years. The infection rate in the group without addition of antibiotics was 6,3 or 4,1% for early or late infections respectively, in the Palacos group, whereas in the Refobacin-Palacos group the rate of early or late infections was only 0,6%. No sensitization in respect of the incorporated gentamycin antibiotic was found.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001843:Bone Cements; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D005839:Gentamicins / Q000008:administration & dosage*; D005860:Germany, West; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000517:prevention & control*; D013997:Time Factors
chemical_list: D001843:Bone Cements; D004338:Drug Combinations; D005839:Gentamicins
vernacular_title: Erfahrungen mit Refobacin-Palacos im Hinblick auf die tiefen Spätinfektionen nach Hüftendoprothesenoperationen.