title: [Comparative study of methods of estimating the hemolytic activity of aqueous plastic extracts. Preliminary report].
abstract: The examination of haemolytic activity of aqueous plastic extracts represents one of the method to evaluate plastics of medical grade. In own examinations different methods were used to estimate the haemolytic activity of aqueous extracts of some toxic materials, e.g. technical gums, epoxides, also silicone resins, which are admitted to medical use. On the basis of literature and own examinations the most sensitive method to estimate the haemolytic test was found to be the method after the Japanese Pharmacopoeia. The degree of haemolysis due to the water extracts both of technical gums and epoxides was found to be significantly different from the norms. The silicone resins fulfilled the demands for medical materials. On the basis of the results, the method described in the Japanese Pharmacopoeia was accepted as an appropriate test for evaluation of haemolytic activity of aqueous plastic extracts designed to blood contact or to implantation.
mesh_terms: D006461:Hemolysis; D006801:Humans; D008722:Methods; D011091:Polyesters / Q000592:standards* / Q000633:toxicity
chemical_list: D011091:Polyesters
vernacular_title: Badania porównawcze metod oznaczania działania hemolitycznego wyciagów wodnych z tworzyw sztucznych. Doniesienie tymczasowe.