New antibiotics from the fungus Epicoccum nigrum. I. Fermentation, isolation and antibacterial properties.
An atmosphere isolate of the fungus Epicoccum nigrum was found to exhibit an activity against Staphylococcus aureus. A more active, non-sporulating variant of this strain was selected. From its fermentation broth, two novel compounds, epicorazines A and B, were isolated by preparative TLC and tested against a series of bacteria.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000302:isolation & purification / Q000494:pharmacology; D002177:Candidiasis / Q000378:metabolism*; D005285:Fermentation; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents