[Drepanocytic retinopathy (author's transl)].
Hemoglobinopathies and specially drepanocytosis SS and its heterozygotic form SC are responsible of important pathological changes of retina. These changes caused by ischaemia due to vascular thrombosis are generally silent at their beginning, because of their first development in a peripheral area. They have a tendency to progress towards the posterior pole and to get complicated by hemorrhages and detachment of retina. Their study is still to be completed but these disorders already appear as being an important cause of blindness in the populations concerned by this hemoglobinopathy. Treatment is unsatisfactory.
D000755:Anemia, Sickle Cell / Q000150:complications* / Q000235:genetics / Q000503:physiopathology; D006441:Hemoglobin A / Q000032:analysis; D006451:Hemoglobin, Sickle / Q000032:analysis; D006579:Heterozygote; D006801:Humans; D012164:Retinal Diseases / Q000209:etiology* / Q000503:physiopathology; D012166:Retinal Hemorrhage / Q000503:physiopathology; D012171:Retinal Vessels / Q000503:physiopathology
D006451:Hemoglobin, Sickle; D006441:Hemoglobin A
Rétinopathie drépanocytaire.