[Thymus implant in a case of DiGeorge syndrome (author's transl)].
A boy with III-IV pharingeal pouch malformative syndrome, hypocalcemia and recurrent infections is presented. The immunological work-up disclosed deficiency in the specific cellular immunity with normal serum immunoglobulin levels. An adult thymus in Millipore diffusion chambers was implanted in the rectus adominalis muscle. One week later clinical and analytical data suggesting immunological reconstitution was recorded. Two years later the patient remains in good health, T and B lymphocyte percentages are normal, being the only immunological abnormality a low serum level of IgG.
D004062:DiGeorge Syndrome / Q000276:immunology / Q000601:surgery*; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000601:surgery*; D007223:Infant; D008297:Male; D013950:Thymus Gland / Q000637:transplantation*; D014184:Transplantation, Homologous / Q000379:methods
D007136:Immunoglobulins
Implante de timo en un caso de síndrome de DiGeorge.