[Effect of sodium and calcium ions on glutamate and glutamine oxidation by rat brain synaptosomes].
5 mM oxidative substrates and 0.15 mM Ca(2+) being used, different effects of Ca(2+) on the oxidation are possible, such as an additional inhibition of glutamine oxidation and an additional activation of glutamate oxidation. A decreased Na+-ion concentration in the medium inhibited synaptosomal respiration with glutamate as a substrate. With glutamine as a substrate oxygen consumption does not change.
D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000648:ultrastructure; D002118:Calcium / Q000502:physiology*; D002413:Cations, Divalent; D002414:Cations, Monovalent; D004305:Dose-Response Relationship, Drug; D005973:Glutamine / Q000378:metabolism*; D066298:In Vitro Techniques; D010084:Oxidation-Reduction; D051381:Rats; D012964:Sodium / Q000502:physiology*; D013574:Synaptosomes / Q000378:metabolism*
D002413:Cations, Divalent; D002414:Cations, Monovalent; D005973:Glutamine; D012964:Sodium; D002118:Calcium
Vliianie ionov natriia i kal'tsiia na okislenie glutamata i glutamina sinaptosomami golovnogo mozga krys.