title: Calculation of genetic risks in Duchenne muscular dystrophy by geneticists in the United Kingdom.
abstract: Pedigrees of Duchenne muscular dystrophy were sent to 32 geneticists in the United Kingdom, asking for their calculations for genetic risks for female relatives. Eighteen participated, of whom only 7 gave correct answers for all pedigrees. The method most used for calculations (the 'Bayesian' method) was most liable to errors in new situations. An alternative, simpler method is presented.
mesh_terms: D005260:Female; D006580:Genetic Carrier Screening; D005817:Genetic Counseling; D006801:Humans; D008297:Male; D008433:Mathematics; D009136:Muscular Dystrophies / Q000235:genetics*; D010375:Pedigree; D011336:Probability; D012306:Risk; D012737:Sex Factors