title: [Fluorometric method for the determination of naproxen and demethylnaproxen in serum and urine (author's transl)].
abstract: Naproxen and demethylnaproxen can be determined fluorometrically in serum and urine after extraction with dichlorethane, and without prior separation. The detection limit of naproxen and demethylnaproxen is below 0,2 mg/l in serum and below 0,5 mg/l in urine. After incubation of urine with beta-glucuronidase/arylsulfatase, most of the conjugated naproxen and demethylnaproxen can be determined.
mesh_terms: D001192:Arylsulfatases; D005966:Glucuronidase; D006801:Humans; D008722:Methods; D009288:Naproxen / Q000031:analogs & derivatives / Q000032:analysis*; D013050:Spectrometry, Fluorescence
chemical_list: D009288:Naproxen; D001192:Arylsulfatases; D005966:Glucuronidase
vernacular_title: Fluorometrische Methode zur Bestimmung von Naproxen und Desmethylnaproxen in Serum und Urin.