Investigations on general immune reactivity in untreated cervical cancer patients.
74 patients with untreated cervical cancer (FIGO II and III) were skintested with a battery of recall antigens, and also sensitised and challenged with DNCB. A significant reduction of reaction to Tuberkulin, Varidase and also to DNCB was found in patients with stage III in comparison to healthy females of the same age group. Significant changes in immunoglobulin levels, increase of IgA and decrease of IgG were observed in the cancer patients. Serum lysozyme values were the same as in the control group.
D002294:Carcinoma, Squamous Cell / Q000201:enzymology / Q000276:immunology*; D004137:Dinitrochlorobenzene / Q000276:immunology; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed; D007109:Immunity; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D009113:Muramidase / Q000097:blood; D012882:Skin Tests; D002583:Uterine Cervical Neoplasms / Q000201:enzymology / Q000276:immunology*
D004137:Dinitrochlorobenzene; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D009113:Muramidase