Quaternary acetate and propionate esters of 3-hydroxyquinolizidine.
The preparation of the quaternary acetate and propionate esters of 3-hydroxyquinolizidine is described. Tentative structures are assigned on the basis of NMR data. Results of preliminary pharmacological screening of the methiodide and hydrochloride salts are given.
D000109:Acetylcholine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D066298:In Vitro Techniques; D007583:Jejunum / Q000187:drug effects; D008722:Methods; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010277:Parasympathomimetics / Q000037:antagonists & inhibitors / Q000138:chemical synthesis; D011807:Quinolizines / Q000037:antagonists & inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats
D010277:Parasympathomimetics; D011807:Quinolizines; D001285:Atropine; D000109:Acetylcholine