title: Diagnostic problems involved in detection of metastatic neoplasms by bone-marrow aspirate compared with needle biopsy.
abstract: Diagnostic problems involved in detection of metastatic neoplasms by bone-marrow aspirate compared with needle biopsy. Am J Clin Pathol 70: 623--627, 1978. Comparison of a large series of bone marrow aspirations with simultaneously performed Jamshidi needle biopsies showed 75% correlation between the two procedures for detection of metastatic neoplasms. In cases where the two methods disagreed, false-negative aspirations resulting from perineoplastic desmoplasia was the usual reason for the discrepancy. Cytologic criteria for the evaluation of suspected neoplastic cells in aspirate preparations are discussed.
mesh_terms: D001707:Biopsy, Needle; D001853:Bone Marrow / Q000473:pathology; D003238:Connective Tissue / Q000473:pathology; D005188:False Negative Reactions; D006801:Humans; D001239:Inhalation; D009362:Neoplasm Metastasis / Q000175:diagnosis*; D012119:Respiration