Serum factor affecting neutrophil function during acute viral hepatitis.
Sera from eight of 17 patients with acute viral hepatitis was deficient in its ability to support neutrophil bactericidal function in vitro. This defect appeared to be related to the viral infection itself. Sera from patients with drug hepatitis or mechanical obstructive jaundice did not show this effect.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D001770:Blood Bactericidal Activity; D056486:Chemical and Drug Induced Liver Injury / Q000097:blood; D002779:Cholestasis / Q000097:blood; D005260:Female; D006525:Hepatitis, Viral, Human / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000502:physiology*; D013211:Staphylococcus aureus