title: Synthesis of benzo-benzothiopyranoquinolines (pyridobenzothioxanthones) as possible schistosomicidal and antitumor agents.
abstract: The synthesis of a new class of compounds structurally related to cyclohexenothiaxanthones and benzothiaxanthones including a pyridine ring is described in an attempt to find compounds that may have schistosomicidal and carcinostatic activity. Synthesis was achieved through the condensation of amino-cyclohexenothiaxanthones and amino-benzothiaxanthones with ethyl acetoacetate by the Knorr and Conrad-Limpach methods.
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents; D055598:Chemical Phenomena; D002621:Chemistry; D008722:Methods; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology; D012556:Schistosomicides
chemical_list: D000970:Antineoplastic Agents; D011804:Quinolines; D012556:Schistosomicides