Megavitamins for minimal brain dysfunction. A placebo-controlled study.
Preliminary to a stimulant comparison study, 31 children with minimal brain dysfunction randomly received either placebo or a megavitamin combination. During a two-week trial, only two children responded so well that stiumlants were not considered necessary; both were in the placebo group. Change scores from pretest to posttest on four blind ratings by teachers and parents did not show a significant difference between the placebo and vitamin groups.
D001205:Ascorbic Acid / Q000627:therapeutic use; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy*; D002648:Child; D005260:Female; D005971:Glutamates / Q000627:therapeutic use; D006801:Humans; D006948:Hyperkinesis / Q000188:drug therapy; D007859:Learning Disabilities / Q000188:drug therapy; D008297:Male; D009539:Nicotinic Acids / Q000627:therapeutic use; D009974:Orthomolecular Therapy / Q000379:methods; D010205:Pantothenic Acid / Q000627:therapeutic use; D011736:Pyridoxine / Q000627:therapeutic use
D005971:Glutamates; D009539:Nicotinic Acids; D010205:Pantothenic Acid; D011736:Pyridoxine; D001205:Ascorbic Acid