title: Near-fatal and fatal anaphylactic reactions to insect sting.
abstract: Two patients experienced anaphylactic reaction to insect stings, with residual encephalopathy. One patient had anaphylaxis despite hyposensitization with whole-body extracts, thus supporting recent reports that reliable protection cannot be achieved unless pure venom is used. The other patient had pathologic confirmation of anoxic encephalopathy, thus supporting the concept that encephalopathy with anaphylaxis is secondary to associated circulatory collapse rather than a primary allergic response of brain disease.
mesh_terms: D000485:Allergens; D000707:Anaphylaxis / Q000276:immunology* / Q000401:mortality; D000818:Animals; D001516:Bees; D001927:Brain Diseases / Q000150:complications; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D006927:Hymenoptera; D007299:Insect Bites and Stings / Q000150:complications / Q000276:immunology* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011817:Rabbits; D014118:Toxins, Biological; D014863:Wasps
chemical_list: D000485:Allergens; D014118:Toxins, Biological