title: Production and absorption of cerebrospinal fluid in the spinal subarachnoid space of the dog.
abstract: The formation and absorption capacity of CSF in the isolated spinal subarachnoid space was investigated in seven dogs by using a perfussion of a solution similar to the cerebrospinal fluid labeled with I 131. It was found that there was no CSF production in the spinal canal; however, there was an important absorption rate with an average of 0.2695 ml/min when the intraspinal pressure was of 10 centimeters of water. The clinical implications of this findings are discussed.
mesh_terms: D000042:Absorption; D000818:Animals; D002555:Cerebrospinal Fluid / Q000378:metabolism*; D004285:Dogs; D007457:Iodine Radioisotopes; D013346:Subarachnoid Space / Q000378:metabolism*; D013997:Time Factors
chemical_list: D007457:Iodine Radioisotopes