Reduction of the cerebellar stimulus effect on rat Deiters neurons after chemical destruction of the inferior olive.
After the inferior olive of the rats had been destroyed by administration of 3-Acetylpyridine, the inhibitory effect of cerebellar stimulation on Deiters neurons was substantially reduced, indicating impairment in functions of Purkinje cells and/or their axons after deprivation of climbing fiber afferents from the cerebellum.
D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D002531:Cerebellum / Q000502:physiology*; D004558:Electric Stimulation; D009433:Neural Inhibition; D009474:Neurons / Q000502:physiology*; D009847:Olivary Nucleus / Q000187:drug effects / Q000502:physiology*; D011689:Purkinje Cells / Q000187:drug effects / Q000502:physiology; D011725:Pyridines / Q000494:pharmacology; D051381:Rats; D013997:Time Factors
D011725:Pyridines