title: Familial sinus node dysfunction with autosomal dominant inheritance.
abstract: A large family with sinus node dysfunction is described, spanning three generations and with an autosomal dominant trait. There was an obvious association between the grade of mental retardation and the severity of the sinoatrial disorder.
mesh_terms: D000328:Adult; D001146:Arrhythmia, Sinus / Q000235:genetics*; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics; D010375:Pedigree