Vitreous fluorophotometry evaluation of xenon photocoagulation.
An abnormal increase in the permeability of the outer blood-retinal barrier was induced in the eyes of adult pigmented rabbits after retinal xenon arc photocoagulation. The alteration of the blood-retinal barrier, which was assessed by vitreous fluorophotometry after systemic administration of sodium fluorescein, followed a well-defined pattern. Higher values, which were recorded during the first three days after photocoagulation, recovered progressively afterward. The permeability of the blood-retinal barrier returned to near-normal levels between 10 and 14 days after photocoagulation. A direct correlation was observed between higher initial values and heavier photocoagulation.
D000818:Animals; D002199:Capillary Permeability; D005452:Fluoresceins / Q000032:analysis; D008028:Light Coagulation / Q000009:adverse effects*; D010783:Photometry; D011817:Rabbits; D012171:Retinal Vessels / Q000503:physiopathology*; D014822:Vitreous Body / Q000032:analysis; D014978:Xenon
D005452:Fluoresceins; D014978:Xenon