title: [Production of trivalent vaccine against avian spirochetosis].
abstract: Reshetnyak's method was employed to produce a trivalent vaccine against avian spirochetosis, using the serotypes Surnevo I, Pamoukchii, and Venets established in this country. The vaccine was tested for sterility, innocuity, and immunogenicity. Its activity was determined via biologic titration on birds. The vaccine was shown to protect birds against the disease when used at the rate of 0.5 cm3. Six (13.3%) out of all vaccinated birds contracted spirochetosis within various periods following vaccination. It was found that the duration of postvaccinal immunity after treatment with the trivalent vaccine lasted eight months (the time of observation). The vaccine protected 86.7% of the treated birds against spirochetosis.
mesh_terms: D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage; D002031:Bulgaria; D002645:Chickens; D011201:Poultry Diseases / Q000517:prevention & control*; D013145:Spirochaetales Infections / Q000517:prevention & control / Q000662:veterinary*; D014611:Vaccination / Q000662:veterinary*
chemical_list: D001428:Bacterial Vaccines
vernacular_title: Opiti za poluchvane na trivalentna vaksina sreshtu spirokhetoza po ptitsite.