Inhibition of glycine synthase by branched-chain alpha-keto acids. A possible mechanism for abnormal glycine metabolism in ketotic hyperglycinemia.
D000138:Acidosis / Q000378:metabolism*; D000214:Acyl Coenzyme A / Q000494:pharmacology; D000818:Animals; D002208:Caproates / Q000494:pharmacology; D005998:Glycine / Q000378:metabolism*; D007651:Keto Acids / Q000494:pharmacology*; D007662:Ketosis / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008297:Male; D051381:Rats; D014166:Transferases / Q000378:metabolism*; D014631:Valerates / Q000494:pharmacology
D000214:Acyl Coenzyme A; D002208:Caproates; D007651:Keto Acids; D014631:Valerates; D014166:Transferases; D005998:Glycine