The secretin-CCK test and a modified Lundh test. A comparative study.
A comparison has been made between a modified Lundh test and the secretin-CCK test. Thirty-four patients with pancreatic disease (chronic pancreatitis, n = 25; recurrent pancreatitis, n = 5; and pancreatic carcinoma, n = 4) and 20 patients with other gastrointestinal disorders were studied. The results showed that estimation of trypsin secretion, irrespective of the mode of stimulation, had a low sensitivity in detecting pancreatic disease. Estimation of bicarbonate secretion after secretin stimulation provided a more sensitive test, especially for disclosing chronic pancreatitis.
D000328:Adult; D000368:Aged; D001639:Bicarbonates / Q000378:metabolism*; D002766:Cholecystokinin; D004386:Duodenum; D005502:Food; D005767:Gastrointestinal Diseases / Q000175:diagnosis*; D006801:Humans; D007441:Intubation, Gastrointestinal; D008722:Methods; D008875:Middle Aged; D010189:Pancreatic Juice / Q000201:enzymology / Q000378:metabolism*; D010190:Pancreatic Neoplasms / Q000175:diagnosis*; D010195:Pancreatitis / Q000175:diagnosis*; D012008:Recurrence; D012633:Secretin; D012636:Secretory Rate; D014357:Trypsin / Q000378:metabolism*
D001639:Bicarbonates; D012633:Secretin; D002766:Cholecystokinin; D014357:Trypsin