Clinical and neurobehavioral effects of repeated intrauterine exposure to oxytocin: a prospective study.
A prospective investigation of 114 pregnant women compared 54 with consistently negative oxytocin challenge tests to 60 women who did not have oxytocin challenge tests but did have fetal monitoring during labor. Despite more high risk factors in the OCT group, there were no significant differences noted in the offspring. Specifically, extensive behavioral testing during the first 12 hours of life and at 3 days of age did not show any abnormalities. Furthermore, jaundice and respiratory distress were not seen more often after oxytocin exposure. These data argue that the OCT itself is without demonstrable adverse effects on the otherwise healthy fetus.
D000328:Adult; D002652:Child Behavior / Q000187:drug effects; D005260:Female; D005323:Fetal Monitoring; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D010121:Oxytocin / Q000009:adverse effects*; D011247:Pregnancy; D011446:Prospective Studies; D012306:Risk
D010121:Oxytocin