Properties of a persistent viral infection: possible lysogeny by an enveloped nonlytic mycoplasmavirus.
MVL2, an enveloped double-stranded DNA mycoplasmavirus, causes a nonlytic infection of Acholeplasma laidlawii leading to the establishment of a persistent infection. Persistently infected clones were found to be resistant to superinfection by homologous virus, but could be infected by heterologous virus. Cells in a persistently infected culture had the potential to produce virus and transmitted this potential as a stable heritable trait. Mitomycin C and UV light induced an increase in infectious centers in persistently infected cultures.
D000128:Acholeplasma laidlawii / Q000187:drug effects / Q000528:radiation effects; D001435:Bacteriophages / Q000254:growth & development*; D008242:Lysogeny; D008937:Mitomycins / Q000494:pharmacology; D014466:Ultraviolet Rays; D014764:Viral Proteins; D014779:Virus Replication / Q000187:drug effects / Q000528:radiation effects
D008937:Mitomycins; D014764:Viral Proteins