title: Local anaesthetic plasma levels in children.
abstract: Blood levels of lignocaine and bupivacaine were measured in children following caudal, subcutaneous and tracheal administration. The highest peak levels were in children under 3 years following tracheal spray but all blood levels were below accepted toxic adult levels for anaesthetised patients. No toxic manifestations were seen.
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000763:Anesthesia, Caudal; D000779:Anesthetics, Local / Q000097:blood*; D002045:Bupivacaine / Q000008:administration & dosage / Q000097:blood; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007279:Injections, Subcutaneous; D008012:Lidocaine / Q000008:administration & dosage / Q000097:blood
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine; D002045:Bupivacaine