beta-Sitosterol as a nonabsorbable marker of dietary lipid absorption in man.
beta-[14C]Sitosterol was evaluated for its usefulness as a nonabsorbable marker of lipid absorption in intubation studies. A liquid meal, including [3H]triolein as a marker of absorbable lipid, was used. The beta-sitosterol was shown to remain well mixed with triolein in the gastric antrum, validating its suitability for this type of study. In small bowel fluid, the beta-sitosterol was shown to partition into the aqueous phase in proportion to triolein and its hydrolysis products. With this system, lipid absorption was shown to take place chiefly in the jejunum in normal individuals.
D002250:Carbon Radioisotopes; D004041:Dietary Fats; D006801:Humans; D007408:Intestinal Absorption; D007553:Isotope Labeling / Q000379:methods; D008297:Male; D012855:Sitosterols / Q000378:metabolism*; D014304:Triolein / Q000378:metabolism
D002250:Carbon Radioisotopes; D004041:Dietary Fats; D012855:Sitosterols; D014304:Triolein