title: Potato spindle tuber viroid: circular dichroism spectrum and physical chemical studies of its interaction with ethidium bromide.
abstract: The presence and extent of base-paired secondary structure in the protein-free potato spindle tuber viroid RNA has been investigated by spectroscopic techniques. Dye-binding studies with the intercalating dye, ethidium bromide, indicate the presence of base-paired regions in the molecule. Variation of the induced chirality in the dye with the dye to RNA phosphate ratio indicate the presence of two base-paired regions in the molecule.
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002942:Circular Dichroism; D004996:Ethidium; D009690:Nucleic Acid Conformation; D010942:Plant Viruses; D012328:RNA Viruses; D012367:RNA, Viral / Q000032:analysis; D012265:Ribonucleotides / Q000032:analysis
chemical_list: D012367:RNA, Viral; D012265:Ribonucleotides; D004996:Ethidium