Antitumor Plants. V. Constituents of Cinchona pubescens.
The stem bark and stem wood of Cinchona pubescens were found to owe their weak cytotoxic activity to the presence of quinovic acid. This acid and its 3-rhamnoside were isolated and characterized through several derivatives, all of which were assayed for their cytotoxicity.
D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000627:therapeutic use; D002929:Cinchona / Q000032:analysis*; D009374:Neoplasms, Experimental / Q000188:drug therapy; D008517:Phytotherapy; D010946:Plants, Medicinal
D000972:Antineoplastic Agents, Phytogenic