title: [Kidney reaction to an increase in the volume of extracellular fluid in rabbits with ischemic cerebral hypertension].
abstract: The excretion of water, electrolytes and osmotically active substances and the blood plasma natriuretic activity were studied following isotonic dilation of the extracellular space in experiments on rabbits with ischemic cerebral hypertension. Rabbits with hypertension were marked by the phenomenon of exaggerated natriuresis and increased excretion of water and osmotically active substances after volumetric stimulation, which was due to a greater inhibition of processes of tubular reabsorption than in intact animals. The increase in the content of the natriuretic factor in the blood plasma of rabbits with ischemic cerebral hypertension after an increase in the volume of extracellular fluid could not be identified as one of the possible causes of inhibition of sodium reabsorption.
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000503:physiopathology*; D004231:Diuresis; D005110:Extracellular Space / Q000502:physiology*; D006973:Hypertension / Q000503:physiopathology*; D007552:Isotonic Solutions; D007668:Kidney / Q000503:physiopathology*; D007677:Kidney Function Tests; D009318:Natriuresis; D011817:Rabbits; D012965:Sodium Chloride / Q000008:administration & dosage
chemical_list: D007552:Isotonic Solutions; D012965:Sodium Chloride
vernacular_title: Reaktsiia pochek na uvelichenie ob''ema vnekletochnoĭ zhidkosti u krolikov s ishemicheskoĭ tserebral'noĭ gipertonieĭ.