title: [Aseptic bone necrosis in lupus disease].
abstract: Seven cases with aseptic necrosis in lupus disseminatus are presented being 9.70 per cent of 72 patients with confirmed systemic lupus, observed in the cours of 20 years. Six cases with lupus disseminatus are concerned--acute and subacute paroxysm a course and one case with chronic skin form--discoid lupus, complicated in the course of its evolution with aseptic necrosis of the right head of the femur. The cause for detection of the bone lesions in the cases presented, was the pain, especially manifested with the necrosis localized in the supporting bones of the lower limbs. The analysis of the state of the patients with systemic lupus reveals that all cases, are severe forms of the disease with multiorgan involvement, febrile reactions and the presence of vascular phenomena--Raynaud syndrome, coronary and cerebral arteriitis. High doses of corticosteroid preparations were used in the treatment of the disease due to its lasting progress (paroxysms of 8--12 months).
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D005260:Female; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000188:drug therapy / Q000473:pathology*; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010020:Osteonecrosis / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000305:Adrenal Cortex Hormones
vernacular_title: Aseptichni kostni nekrozi pri lupusnata bolest.