title: [Vascular reactivity and catecholamine excretion in hypertension].
abstract: Increased vascular reactivity to noradrenaline was revealed in patients with Stages I and II hypertensive disease; the reaction to the sympathomimetic agent of indirect action ephedrine remained at the control level. A salt load increased the discrepancy between the level of the reactions to these two agents. It is suggested that processes of catecholamine storage and excretion in the tissues are disturbed in hypertensive disease and that sodium ions probably take part in this process. The daily excretion of noradrenaline was in negative relation with the reactivity to noradrenaline and correlated positively with the reactivity to angiotensin.
mesh_terms: D000328:Adult; D000804:Angiotensin II; D002395:Catecholamines / Q000652:urine*; D004809:Ephedrine; D006801:Humans; D006973:Hypertension / Q000503:physiopathology* / Q000652:urine; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D002395:Catecholamines; D000804:Angiotensin II; D004809:Ephedrine; D009638:Norepinephrine
vernacular_title: Sosudistaia reaktivnost' i ékskretsiia katekholaminov pri gipertonicheskoĭ bolezni.