[Small scale efficient reproduction of El mice (author's transl)].
Epilepic anormaly strain of mice "El" derived from National Institute of Health, Japan were bred by sister-brother mating during the first 3 months and maintained thereafter by random mating at this laboratory. About 20% (21/101) of virgin females and 4% (2/49) of males were infertile and rate of delivering was relatively poor; mean delivery rate was 70.6%. Delivery rate were drawn after fourth litter. The mean litter size and weaning rate were 7.54 and 97.9%, respectively. Male El mice died following convulsion. Autopsy revealed the obstruction of urether, bleeding in the bladder and seminal vesicules. The time of 50% death was 166 days of age.
D000818:Animals; D001947:Breeding; D004195:Disease Models, Animal; D005260:Female; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains / Q000502:physiology*; D012098:Reproduction; D012376:Rodent Diseases; D012640:Seizures / Q000662:veterinary*