[Decrease in the thrombocyte monoamine oxidase activity of schizophrenic patients].
The authors measured the monoaminoxidase activity in thrombocytes of 28 schizophrenic patients and in 36 normal donors. The monoamine oxidase activity in schizophrenic patients was decreased by 14% and in the subgroup of patients with continuous schizophrenia by 19.5% as compared to that of normals. The monoamine oxidase activity in schizophrenic female patients did not significantly differ from the norm, while the male patients differed highly significantly from the normal. The decrease of monoamine oxidase activity correlated with the level of negative disorders (r = 0,71; P less than 0,01). A correlation with positive disorders was not noted.
D000328:Adult; D001792:Blood Platelets / Q000201:enzymology*; D004796:Clinical Enzyme Tests; D005260:Female; D006801:Humans; D008297:Male; D008995:Monoamine Oxidase / Q000097:blood*; D012559:Schizophrenia / Q000175:diagnosis / Q000201:enzymology*; D012737:Sex Factors
D008995:Monoamine Oxidase
Snizhenie aktivnosti monoaminoksidazy trombotsitov bol'nykh shizofrenieĭ.