[Recognition of female carriers of haemophilia A (author's transl)].
The detection rate for female carriers of haemophilia A was investigated by comparing the one-step method of Hardisty and Macpherson for biological activity of factor VIII with quantitative immunoelectrophoresis (after Laurell) for factor VIII-associated antigen. Certain or probable positive results were obtained in 25 of 27 female carriers by the quantitative immunoelectrophoresis, but only in 18 when measuring factor VIII activity.
D000941:Antigens / Q000032:analysis; D005169:Factor VIII / Q000032:analysis; D005260:Female; D006580:Genetic Carrier Screening; D006467:Hemophilia A / Q000175:diagnosis*; D006801:Humans; D007122:Immunoelectrophoresis
D000941:Antigens; D005169:Factor VIII
Untersuchungen zur Erkennung von Konduktorinnen der Hämophilie A.