title: Concussion: comparison of humans and rats.
abstract: Concussion is the most primitive and probably the most simple central nervous system response to an outside agent. Although millions of neurons undergo a very rapid reversal with loss and restoration of function, many physicians argue that every knockout blow leaves some residual damage, i.e., some or all of these neurons stop short of recovery. Clinical experience shows a wide discrepancy in the appearance or persistence of certain signs and symptoms after all types of head injury, but particularly after concussing blows, when third party or grievance cases are involved. Using slow motion filmstrips of boxing ring knockouts, we established a grading system for concussion and duplicated these grades in nonanesthetized rats. When we compared the performance, learning, and memory of concussed rats with their preconcussion performance and with the performance of nonconcussed controls, we were unable to find any differences.
mesh_terms: D000818:Animals; D001265:Athletic Injuries / Q000175:diagnosis; D001914:Boxing; D001930:Brain Injuries / Q000175:diagnosis*; D004195:Disease Models, Animal; D006801:Humans; D007858:Learning; D008568:Memory; D009040:Motion Pictures; D009043:Motor Activity; D051381:Rats; D012075:Remission, Spontaneous; D012119:Respiration; D013314:Stress, Mechanical