[Disorders of heat and water regulation. Proliferative reticulo granulomatous process of hypothalamic origin (author's transl)].
The authors report the anatomical and clinical findings in a 65 year old patient with a lesion in the hypothalamus presenting mainly as disorders in heat and water regulation. Disorders in heat regulation dominated the clinical picture, in relation to a poikilothermia. Conservation of reactivity to pyrogenic bacteria is debatable. Inappropriate secretion of antidiuretic hormone (ISADH) by a direct effect on the supraoptico-hypophyseal aixs can account for the water and electrolyte disturbances. The anatomical lesions, due to hypothalamic changes, can be included in the circumscribed proliferative reticuloses of the CNS having a pseudo-inflammatory histological appearance.
D000368:Aged; D001833:Body Temperature Regulation; D001927:Brain Diseases / Q000150:complications* / Q000473:pathology; D005334:Fever / Q000209:etiology; D006801:Humans; D007031:Hypothalamus / Q000473:pathology; D007035:Hypothermia / Q000209:etiology; D007177:Inappropriate ADH Syndrome / Q000150:complications; D008297:Male; D014883:Water-Electrolyte Imbalance / Q000209:etiology*
Troubles de la régulation thermique et de la régulation hydrique. Processus prolifératif réticulo-granulomateux à détermination hypothalamique.