Immune prophylaxis of experimental cancer by corynebacterium parvum.
Fractionated administration of C.p. i.v. in mice at risk from sarcomas after injection of 0.2 mg MCA leads to a significant prolongation of the period of latency under certain circumstances. Experimental groups which have received the immune stimulator for 6 weeks immediately after the cancerogenic factor show the best results. After tumour manifestation there is no perceptible preventive effect of C.p.
D000818:Animals; D005260:Female; D008748:Methylcholanthrene; D051379:Mice; D009374:Neoplasms, Experimental / Q000276:immunology / Q000517:prevention & control*; D011425:Propionibacterium acnes / Q000276:immunology*; D013997:Time Factors
D008748:Methylcholanthrene