[Relationship between the ganglioside composition of Ehrlich ascitic carcinoma and cell population density].
The ganglioside composition of Ehrlich ascite carcinoma cells changes drastically with changes in density of the cell population. Upon 30-fold dilution of the native cell suspension and subsequent incubation for 2 h the amount of total gangliosides per cell doubles the quantities of a monosialoganglioside and of a disialoganglioside increase ten- and five-fold, respectively, whereas the other cell gangliosides do not change. The decrease of cell density is supposed to be accompanied by induction on the cell surface of a sialytransferase activity, which appears to be depressed in the dense suspension.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000032:analysis* / Q000473:pathology; D002452:Cell Count; D002855:Chromatography, Thin Layer; D005732:Gangliosides / Q000032:analysis*; D008297:Male; D051379:Mice
D005732:Gangliosides
Zavisimost' gangliozidnogo sostava astsitnoĭ kartsinomy Erlikha ot plotnosti kletochnoĭ populiatsii.