title: Inhibition of thrombin and trypsin by tripeptide aldehydes.
abstract: Inhibitory effects of certain tripeptide aldehydes on both thrombin and trypsin have been found to be strongly substrate-dependent. These compounds should therefore be considered as inhibitors of the particular proteolytic reaction for which they had been designed rather than real enzyme inhibitors, i.e. protein or polypeptide proteinase inhibitors of natural origin.
mesh_terms: D000447:Aldehydes; D010455:Peptides; D013917:Thrombin / Q000037:antagonists & inhibitors*; D014361:Trypsin Inhibitors
chemical_list: D000447:Aldehydes; D010455:Peptides; D014361:Trypsin Inhibitors; D013917:Thrombin