Effect of double partial hepatectomies at various intervals on [3H]thymidine incorporation into rat liver DNA.
At various intervals after a 34% hepatectomy, another 34% (50% of the remnant) hepatectomy was performed on rats, and the [3H]thymidine incorporation into the DNA of remaining liver cells was measured 24 hr after the first operation. The values of [3H]thymidine incorporation into liver DNA of rats hepatectomized doubly (34% and 34%) at 6, 8 and 10 hr intervals were greater than the sum of the value of rats which received a single 34% hepatectomy at the start and those of rats which received a single 68% hepatectomy at 6, 8 and 10 hr, respectively.
D000818:Animals; D002455:Cell Division; D004247:DNA / Q000096:biosynthesis; D006498:Hepatectomy; D008099:Liver / Q000166:cytology* / Q000378:metabolism; D008115:Liver Regeneration; D008297:Male; D051381:Rats; D013997:Time Factors
D004247:DNA