Appearance of maternal anti-JK a antibody following intrauterine transfusions and amniocentesis.
A case is presented that suggests that intrauterine transfusion carries the risk of sensitization to red cell antigens other than Rho. In this case intrauterine transfusions of JK a-positive red cells were followed by the appearance in the mother's serum of anti-JK a, an antibody known to cause hemolytic disease of the newborn. The use of the mother as a donor of red cells for her fetus will circumvent the problem of further maternal sensitization.
D000328:Adult; D000649:Amniocentesis / Q000009:adverse effects*; D000906:Antibodies; D001789:Blood Group Antigens; D001805:Blood Transfusion, Intrauterine / Q000009:adverse effects*; D004899:Erythroblastosis, Fetal / Q000209:etiology / Q000276:immunology; D005260:Female; D006801:Humans; D007667:Kidd Blood-Group System; D011247:Pregnancy
D000906:Antibodies; D001789:Blood Group Antigens; D007667:Kidd Blood-Group System