title: [Continuous cultivation of Penicillium brevicompactum that forms extracellular ribonucleases].
abstract: Conditions for continuous cultivation of Penicillium brevi-compactum producing extra-cellular ribonucleases were studied. The two-step process of fermentation in the course of which the flow of the medium in the first fermenter was maintained at 0.054 hr-1, and in the second fermenter at 0.0527 hr-1, made it possible to produce 3--4 times more enzymes as compared to the batch culture.
mesh_terms: D003470:Culture Media; D004467:Economics; D004790:Enzyme Induction; D010407:Penicillium / Q000201:enzymology* / Q000254:growth & development; D012260:Ribonucleases / Q000096:biosynthesis*; D013997:Time Factors
chemical_list: D003470:Culture Media; D012260:Ribonucleases
vernacular_title: Nepreryvnoe kul'tivirovanie Penicillium brevicompactum, obrazuiushchego vnekletochnye ribonukleazy.