The uveitis-glaucoma-hyphema syndrome associated with the Mark VIII anterior chamber lens implant.
An update on the percentage of my patients showing the UGH syndrome associated with the Mark VIII anterior chamber lens implant as manufactured by Surgidev is given. Of seven patients having the syndrome sufficiently severe to warrant removal of the offending lens, six have now been reimplanted, two each with Rayner, IOLAB, and PC lenses. Whereas, other physicians have observed a similar UGH syndrome associated with iris chafing and erosions, this process was not particularly apparent in my cases involving the Surgidev lens. As for the chafing phenomenon, one could logically assume that it could be in large part eliminated by significantly increasing the curvature of the lens and simply vault the iris to a greater degree than is obtainable with lenses currently on the market. Perhaps too much emphasis has been placed on avoiding the endothelium and not enough emphasis on avoiding the iris.
D000867:Anterior Chamber; D005901:Glaucoma / Q000209:etiology*; D006801:Humans; D006988:Hyphema / Q000209:etiology*; D007910:Lenses, Intraocular / Q000009:adverse effects*; D013577:Syndrome; D014605:Uveitis / Q000209:etiology*