title: Aortic cholesteryl esterase. Influence of bile salts.
abstract: The in vitro activity of cholesteryl ester hydrolase preparations of rat and rabbit aortas was assayed in the presence of the taurine and glycine conjugates of cholic, chenodeoxycholic, deoxycholic and lithocholic acids or in the presence of Triton X-100 and Tween-20. Maximum activity was obtained with tauro- or glycocholic acids. As in the case of pancreatic cholesteryl esterase, trihydroxycholanoic acid derivatives may serve an obligatory function.
mesh_terms: D000818:Animals; D001011:Aorta / Q000201:enzymology*; D001647:Bile Acids and Salts / Q000494:pharmacology*; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism*; D002793:Cholic Acids / Q000494:pharmacology; D006000:Glycocholic Acid / Q000494:pharmacology; D006868:Hydrolysis; D008099:Liver / Q000378:metabolism; D011092:Polyethylene Glycols / Q000494:pharmacology; D011136:Polysorbates / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D002787:Sterol Esterase / Q000096:biosynthesis / Q000378:metabolism*; D013656:Taurocholic Acid / Q000494:pharmacology
chemical_list: D001647:Bile Acids and Salts; D002793:Cholic Acids; D011136:Polysorbates; D011092:Polyethylene Glycols; D013656:Taurocholic Acid; D002265:Carboxylic Ester Hydrolases; D002787:Sterol Esterase; D006000:Glycocholic Acid