Anthelmintic activity of albendazole against Filaroides hirthi lungworms in dogs.
Albendazole given at a dosage rate of 25 to 50 mg/kg twice daily for 5 days killed all but a small proportion and sterilized the few surviving Filaroides hirthi worms in artificially infected Beagle pups. Extensive tissue reaction around the dead worms persisted for an undetermined length of time. However, albendazole treatment of mature stock should prove useful in preventing transmission of F hirthi infection to their offspring and thus provide an efficient means of control.
D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy* / Q000469:parasitology; D004285:Dogs; D005260:Female; D008168:Lung / Q000469:parasitology; D008174:Lung Diseases, Parasitic / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D008681:Metastrongyloidea / Q000033:anatomy & histology; D009349:Nematode Infections / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*
D000871:Anthelmintics; D001562:Benzimidazoles