[Effect of proteolysis inhibitors on serum proteinase activity and its antitryptic activity in postischemic toxemia].
Parenteral administration to animals of the antikallikrein serum containing 200gamma/ml of antibodies to the pancreatic kallikrein (10 ml/kg), ingitryl (1.5 Un/kg) and of tracilol (10 000 Un/kg) exerts in post-ischemic toxemia an inhibiting effect on the protamine-splitting blood serum activity and does not affect the benzoylarginine-paranitroanilide rate of splitting. Changes of the blood serum ability to bind trypsin and manifestation of the protamine-splitting activity during the first 9 hours of observation are of an undulating nature and the changes of these characteristics are reciprocal.
D000818:Animals; D001586:Benzoylarginine Nitroanilide; D007116:Immunization, Passive; D007511:Ischemia / Q000628:therapy*; D007610:Kallikreins / Q000276:immunology; D008297:Male; D010447:Peptide Hydrolases / Q000097:blood*; D011479:Protamines; D051381:Rats; D014357:Trypsin / Q000276:immunology; D014361:Trypsin Inhibitors / Q000097:blood*
D011479:Protamines; D014361:Trypsin Inhibitors; D001586:Benzoylarginine Nitroanilide; D010447:Peptide Hydrolases; D007610:Kallikreins; D014357:Trypsin
Vliianie ingibitorov proteoliza na aktivnost' proteinaz syvorotki krovi i ee antitripticheskuiu aktivnost' pri postishemicheskom toksemii.