Buckley's syndrome.
An infant girl with chronic eczema, recurrent infections, elevated IgE and impaired neutrophil chemotaxis appeared to belong to the group of patients described by Buckley, Wray & Belmaker (1972). An hereditary influence is suggested by a similar defect found in the patient's mother. Levamisole improved the in vitro defect and the clinical picture.
D002634:Chemotaxis, Leukocyte; D002675:Child, Preschool; D004485:Eczema / Q000188:drug therapy / Q000276:immunology*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000188:drug therapy / Q000276:immunology*; D007978:Levamisole / Q000627:therapeutic use; D009504:Neutrophils / Q000276:immunology; D013577:Syndrome
D007978:Levamisole; D007073:Immunoglobulin E