title: [Dynamics of the changes in thyroid gland parenchyma on thyrocalcitonin administration].
abstract: Experiments were conducted on rats; a study was made of the effect of thyrocalcitonin (TCT) administration--5 Units a day--on thyroid gland. TCT administration during the first 5 days led to structural-functional reconstruction of the gland and activation of the synthesis and elimination of the iodine-containing hormones. Prolonged action of the iodine-containing hormones. Prolonged action of TCT (for 20 days) caused hypofunction of the gland, suppression of endogenous TCT production; it also intensified connective tissue proliferation, and destructive focal changes of the thyroid parenchyma.
mesh_terms: D000818:Animals; D002116:Calcitonin / Q000494:pharmacology*; D003593:Cytoplasm / Q000187:drug effects / Q000648:ultrastructure; D008297:Male; D051381:Rats; D013961:Thyroid Gland / Q000187:drug effects* / Q000648:ultrastructure; D013997:Time Factors
chemical_list: D002116:Calcitonin
vernacular_title: Dinamika izmeneniĭ parenkhimy shchitovidnoĭ zhelezy pri vvedenii tireokal'tsitonina.