Cognitive functions in manic-depressives: effects of lithium and physostigmine.
Cognitive functions were investigated in seven manic depressive patients while on lithium, after two weeks off lithium, and after a subcutaneous injection of physostigmine while on lithium. Test performance was unaffected by lithium, but after physostigmine the I.Q. score of a shortened version of the WAIS was significantly increased.
D001714:Bipolar Disorder / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology*; D003071:Cognition / Q000187:drug effects*; D006801:Humans; D007279:Injections, Subcutaneous; D008094:Lithium / Q000494:pharmacology* / Q000627:therapeutic use; D010830:Physostigmine / Q000008:administration & dosage / Q000494:pharmacology*; D011581:Psychological Tests
D008094:Lithium; D010830:Physostigmine