title: [A contribution as to the effect of (+)-Cyanidanol-3 in chronic liver disease (author's transl)].
abstract: In an open controlled multicenter study the effectiveness of various dose levels of (+)-Cyanidanol-3 (Catergen) in patients suffering from chronic liver disease and treated over a period of 6 months is assessed. Subjective symptoms as fatigue, nausea, loss of appetite, vomiting and pruritus are positively influenced at all dose levels. A statistically significant fall of the transaminases SGOT, SGPT and gamma--GT however occurs only at a dosage of 6 tablets per day (3000 mg per day) of (+)-Cyanidanol-3, which cannot be demonstrated at a dose level of 3 X 1 tablet per day. Between the dosage of 2 X 3 or 3 X 2 tablets per day is no significant difference. Side effects due to therapy could not be observed.
mesh_terms: D001578:Benzopyrans / Q000627:therapeutic use*; D002392:Catechin / Q000627:therapeutic use*; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008107:Liver Diseases / Q000188:drug therapy*
chemical_list: D001578:Benzopyrans; D002392:Catechin
vernacular_title: Ein Beitrag zur Wirkung von (+)-Cyanidanol-3 bei chronischen Hepatopathien.