[Specificity of the action of the RNA released by Ehrlich carcinoma cells on the transplantability and growth of a homologous tumor].
A comparative study was undertaken on the effect of different RNA preparations on the transplatability and growth of Ehrlich carcinoma. The RNA isolated from Ehrlich carcinoma ascites fluid was found to render the specific stimulating action on the transplantability and growth of a homologous tumor, while total RNA from bovine liver, tRNA from rabbit liver and synthetic polyribonucleotides show no stimulating effect. The RNA from Ehrlich carcinoma ascites fluid is formed as a result of its release from intact tumor cells, and it seems to be one of the factors responsible for the interaction between the tumor and the organism.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism* / Q000503:physiopathology; D002417:Cattle; D002455:Cell Division / Q000187:drug effects; D051379:Mice; D009368:Neoplasm Transplantation; D011061:Poly A / Q000494:pharmacology; D011063:Poly A-U / Q000494:pharmacology; D011072:Poly U / Q000494:pharmacology; D012313:RNA / Q000494:pharmacology; D012334:RNA, Neoplasm / Q000494:pharmacology*; D012343:RNA, Transfer / Q000494:pharmacology; D011817:Rabbits; D013268:Stimulation, Chemical
D012334:RNA, Neoplasm; D011063:Poly A-U; D011061:Poly A; D011072:Poly U; D012313:RNA; D012343:RNA, Transfer
Spetsifichnost' deĭstviia RNK, vydeliaemoĭ kletkami kartsinomy Erlikha, na privivaemost' i rost gomologichnoĭ opukholi.