Pendred's syndrome in a rural Zambian family.
A family is reported in which, in one generation, there are more members with goitres and nerve deafness than expected. It is postulated that these abnormalities are due to Pendred's Syndrome and the reasons for this are discussed. An associated finding in three goitrous patients is tuberculoid leprosy.
D003638:Deafness / Q000235:genetics; D005260:Female; D006042:Goiter / Q000235:genetics*; D006319:Hearing Loss, Sensorineural / Q000235:genetics*; D006801:Humans; D007918:Leprosy / Q000235:genetics; D008297:Male; D013577:Syndrome; D015024:Zambia