Competition of normal beta chains and sickle haemoglobin beta chains for alpha chains as a post-translational control mechanism.
D000755:Anemia, Sickle Cell / Q000378:metabolism*; D006441:Hemoglobin A / Q000096:biosynthesis*; D006451:Hemoglobin, Sickle / Q000096:biosynthesis*; D006801:Humans; D046911:Macromolecular Substances; D011485:Protein Binding; D014176:Protein Biosynthesis; D012805:Sickle Cell Trait / Q000378:metabolism*; D013789:Thalassemia / Q000378:metabolism*
D006451:Hemoglobin, Sickle; D046911:Macromolecular Substances; D006441:Hemoglobin A