[Plasmoblastic and immunoblastic sarcoma. Differentiation of immunoglobulin-producing tumors (myeoloma multiplex, plasmacytoma)].
In the Department of the Pathology of the University of Pécs in 1953--1977 autopsy of 58 cases of myeloma multiplex (MM) and plasmacytoma (P) was performed and among them 4 cases of sarcoma was found. In the material of the Cytologic Center of the Academical Commission of Pécs two more cases of sarcoma occurred. According to the authors findings in the MM-autopsy material (I) in addition to the frequent "plasmocytic-plasmoblastic MM" in a few number (II) immunoblastic tumours could also be seen (immunoblastic MM). "Immunoblastic MM" disseminates more frequently (lymph nodes, spleen, kidney, liver) and the patients die earlier than in cases of "plasmocytic-plasmoblastic MM". Since sarcomatous changes appear to be polymorph and disseminated, for the reliable diagnosis examination of tissue specimens taken from several parts of the tumour is necessary. Recent data and the authors studies show, that immunoglobulin-producing tumours differ each other according to the degree of maturity of plasma cells
D001344:Autopsy; D001853:Bone Marrow / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism; D008297:Male; D009101:Multiple Myeloma / Q000378:metabolism / Q000473:pathology*; D009194:Myeloma Proteins / Q000378:metabolism; D010954:Plasmacytoma / Q000378:metabolism / Q000473:pathology*; D012509:Sarcoma / Q000473:pathology*
D007136:Immunoglobulins; D009194:Myeloma Proteins
Plasmoblastos és immunoblastos sarcoma. Immunglobulint termelö tumorok (myeloma multiplex, plasmocytoma) differenciáltságáról.