title: [Interim results of the SIOP study (author's transl)].
abstract: Since 1975, the International Society of Paediatric Oncology has been carrying on a cooperative therapeutic trial, the aim of which is to find out whether adjuvant chemotherapy with vincristine and CCNU, added to standarized radiotherapy of the whole central nervous system, can improve life expectancy in medulloblastoma and high-grade ependymoma. Up to 1st July, 1977, 164 patients from 14 different countries had been entered into the trial. Up to now, results do not yet permit a statistically valid conclusion as to the superiority of one method of treatment over the other.
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000188:drug therapy*; D002648:Child; D004806:Ependymoma / Q000188:drug therapy*; D006801:Humans; D008130:Lomustine / Q000008:administration & dosage / Q000627:therapeutic use; D008527:Medulloblastoma / Q000188:drug therapy*; D008722:Methods; D014750:Vincristine / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D008130:Lomustine
vernacular_title: Vorläufige Ergebnisse der SIOP-Studie.