[Bartter's syndrome. Pathophysiology in three cases (author's transl)].
The primary pathologic defect in Bartter's syndrome is unknown. Three patients have been studied. In two of them, with normal intra-erythrocite sodium concentration, authors prove the existence of an impaired proximal tubular sodium reabsorption. In the last case, with a high intra-erythrocite sodium concentration, this impaired sodium reabsorption was localized in the proximal and distal tubular portions.
D000328:Adult; D001477:Bartter Syndrome / Q000378:metabolism / Q000503:physiopathology*; D002463:Cell Membrane Permeability; D004912:Erythrocytes / Q000032:analysis / Q000378:metabolism*; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000503:physiopathology*; D007684:Kidney Tubules / Q000503:physiopathology*; D007686:Kidney Tubules, Distal / Q000378:metabolism / Q000503:physiopathology*; D008297:Male; D009994:Osmolar Concentration; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000032:analysis / Q000378:metabolism*
D012964:Sodium; D011188:Potassium
Síndrome de Bartter. Aspectos fisiopatológicos.