[The influence of tinofedrine on fibrinogen and platelet aggregation in patients with recent cerebral infarction (author's transl)].
The influence of Tinofedrine (0.12--0.17 mg/kg. bodyweight) on fibrinogen and platelet aggregation has been investigated in 45 patients (mean age 65 years) with recent cerebral infarction. Depending on the duration of medication a significant decrease of the fibrinogen level as well as of enhanced platelet aggregation has been observed. It is concluded from the present results that the decrease of enhanced platelet aggregation may be mediated by the fall of fibrinogen.
D000368:Aged; D001592:Benzyl Alcohols / Q000494:pharmacology* / Q000627:therapeutic use; D001593:Benzyl Compounds / Q000494:pharmacology*; D002544:Cerebral Infarction / Q000188:drug therapy*; D002560:Cerebrovascular Circulation / Q000187:drug effects; D005260:Female; D005340:Fibrinogen / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects*; D013876:Thiophenes / Q000494:pharmacology* / Q000627:therapeutic use
D001592:Benzyl Alcohols; D001593:Benzyl Compounds; D013876:Thiophenes; D005340:Fibrinogen; C018159:tinofedrine
Die Wirkung von Tinofedrin auf Fibrinogen und spontane Thrombozytenaggregation bei Patienten mit zerebrovaskulärer Insuffizienz.