Stacking interaction of nucleobases: NMR investigations. III. Molecular aspects of the solvent dependence.
The stacking interaction between nucleic acid bases has been investigated by the determination of the self-association of 6-methylpurine in various mixtures of water and nonaqueous solvents in order to elucidate the solvent effect. The parameters of stacking association as well as of local solvent-solute interactions have been measured by means of NMR technique. The influences of local hydration and of solvent-solvent interactions on the stacking ability are discussed.
D001483:Base Sequence; D055598:Chemical Phenomena; D002621:Chemistry; D009682:Magnetic Resonance Spectroscopy; D008433:Mathematics; D009690:Nucleic Acid Conformation; D011687:Purines; D012997:Solvents; D014867:Water
D011687:Purines; D012997:Solvents; D014867:Water; C016588:6-methylpurine