title: The effects of adrenalectomy and cortisol treatment on cell types, other than corticotrophs, in the anterior pituitary of the mouse.
abstract: This investigation was designed to characterize changes due to adrenalectomy and cortisol treatment in cell types, other than corticotrophs, in the anterior pituitary of the mouse. Cortisol injections resulted in a reduced number of mammotrophs and an increased number of somatotrophs. By 5 days post-adrenalectomy an increase in the number of mammotrophs and a decrease in the number of somatotrophs was observed. No changes were noted in the number of gonadotrophs or thyrotrophs due to either adrenalectomy or cortisol treatment.
mesh_terms: D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D005260:Female; D006065:Gonadotropins, Pituitary; D013006:Growth Hormone; D006854:Hydrocortisone / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009940:Organoids / Q000648:ultrastructure; D010903:Pituitary Gland, Anterior / Q000166:cytology* / Q000187:drug effects; D011388:Prolactin; D013972:Thyrotropin
chemical_list: D006065:Gonadotropins, Pituitary; D011388:Prolactin; D013972:Thyrotropin; D013006:Growth Hormone; D006854:Hydrocortisone