Stability of neutrophil-releasing activity of plasma obtained from leukapheresed rats and stored at 4 C.
When granulocyte-donor rats were treated prior to pheresis with plasma obtained from previously leukapheresed rats (PPP), granulocytosis and a significant increase in granulocyte yield were observed. Previous studies have demonstrated that such plasma stored at -150 C for up to two weeks preserved the neutrophil-releasing activity. This study demonstrates that neutrophil-releasing activity was satisfactorily preserved when plasma from previously leukapheresed rats was stored at 4 C for three weeks.
D000818:Animals; D001772:Blood Cell Count; D003080:Cold Temperature; D006098:Granulocytes; D007937:Leukapheresis; D009504:Neutrophils / Q000378:metabolism*; D051381:Rats