[Pharmacologic characteristics of triftazin syrup].
The neurotropic activity, toxicity and pharmacokinetics of triftazine in the form of syrup and powder were subjected to a comparative study on albino mice, rats and dogs. Investigations demonstrated that as follows from the tests under study these drugs display an egual depressing activity. Triftazine from the syrup was found to quicker enter the blood and was detected later in it (after 24 hours). The toxicity of peroral triftazine administered to mice and rats is the same for both dosage forms, it being somewhat higher for intraperitoneal triftazine syrup.
D000284:Administration, Oral; D000661:Amphetamine / Q000008:administration & dosage; D000818:Animals; D004285:Dogs; D004357:Drug Synergism; D051379:Mice; D009949:Orientation / Q000187:drug effects; D011208:Powders; D051381:Rats; D012996:Solutions; D013874:Thiopental / Q000008:administration & dosage; D014268:Trifluoperazine / Q000008:administration & dosage* / Q000097:blood / Q000633:toxicity
D011208:Powders; D012996:Solutions; D014268:Trifluoperazine; D000661:Amphetamine; D013874:Thiopental
Farmakologicheskaia kharakteristika triftazina-siropa.