Polyamine levels in human semen of unfertile patients: effect of S-adenosylmethionine.
Polyamine content has been determined in the seminal plasma of unfertile men before and after S-adenosylmethionine treatment. Spermine and spermidine levels in azoospermic patients were found very low (80 and 24 microgram/ml) with respect to normospermic (1500 and 60 microgram/ml): S-adenosylmethionine treatment enhanced polyamine content (50-300%) in oligospermic patients. Furthermore, an increase of sperm count and motility has been observed in these patients.
D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy*; D008297:Male; D012436:S-Adenosylmethionine / Q000627:therapeutic use*; D012661:Semen / Q000032:analysis*; D013081:Sperm Motility; D013095:Spermidine / Q000032:analysis*; D013096:Spermine / Q000032:analysis*
D013096:Spermine; D012436:S-Adenosylmethionine; D013095:Spermidine