Naevoid basal cell carcinoma syndrome and Charcot-Marie-Tooth disease: two autosomal dominant disorders segregating in a family.
A family is described in which 16 individuals in 3 generations have Charcot-Marie-Tooth disease. At least 6 family members also have the naevoid basal cell carcinoma syndrome. In addition, 1 subject with both disorders has 2 young daughters with the naevoid basal cell carcinoma syndrome.
D000328:Adult; D002280:Basal Cell Carcinoma / Q000150:complications / Q000235:genetics*; D002607:Charcot-Marie-Tooth Disease / Q000150:complications / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D003560:Cysts / Q000150:complications / Q000235:genetics*; D005260:Female; D006801:Humans; D007573:Jaw Neoplasms / Q000150:complications / Q000235:genetics*; D009133:Muscular Atrophy / Q000235:genetics*; D009506:Nevus / Q000150:complications / Q000235:genetics*; D010375:Pedigree