title: Reinnervation of the rat adrenal medulla transplanted in the anterior eye chamber.
abstract: Adrenal medulla transplanted to the anterior chamber of the eye was studied by electron microscopy. Transplanted chromaffin cells consisted of noradrenaline cells, adrenaline cells and small granule-containing cells, and they formed long cytoplasmic processes. Some chromaffin cells were directly opposed to the iridial epithelial cells. A few adrenergic and cholinergic ganglion cells were seen in the transplant. Nerve fibres, mostly cholinergic, but a few adrenergic, were seen within satellite cells enclosing chromaffin and ganglion cells. A few synapses were formed on the chromaffin and ganglion cells, though the number of such synapses remained small even 6 months after transplantation. The possible origin of these nerve fibres, and the specificity of reinnervation are discussed.
mesh_terms: D000313:Adrenal Medulla / Q000294:innervation* / Q000637:transplantation / Q000648:ultrastructure; D000818:Animals; D000867:Anterior Chamber; D002838:Chromaffin System / Q000648:ultrastructure; D008854:Microscopy, Electron; D009416:Nerve Regeneration; D009474:Neurons / Q000648:ultrastructure; D051381:Rats; D014184:Transplantation, Homologous