Abnormal liver cholesteryl ester storage in a strain of golden hamsters. Possible model for studies on cholesterol metabolism.
Very high values of hepatic cholesteryl esters were found in a strain of golden hamsters isolated in our laboratory: 2 g/100 g in animals kept at 22 degrees C and more than 10 g/100 g in starved cold-adapted animals. The rate of incorporation of labelled mevalonate was not increased, but the esterification of the newly-synthetized cholesterol was markedly stimulated.
D000818:Animals; D002784:Cholesterol / Q000378:metabolism*; D002788:Cholesterol Esters / Q000378:metabolism*; D006224:Cricetinae; D005227:Fatty Acids / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008647:Mesocricetus; D008798:Mevalonic Acid / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D013045:Species Specificity; D013217:Starvation; D014280:Triglycerides / Q000378:metabolism
D002788:Cholesterol Esters; D005227:Fatty Acids; D010743:Phospholipids; D014280:Triglycerides; D002784:Cholesterol; D008798:Mevalonic Acid