[Hydrolytic enzymes of rat tissues with adjuvant arthritis].
Tissues of rats with adjuvant arthritis manifested differences in activity and distribution between free, latent and membrane-bound forms of acid catepsins, alpha-D- and beta-D-galactosidases, alpha-D- and beta-D-glucosidases, beta-D-glucorunidase, hyaluronidase, acid phosphatase, arylsulphatases (A+B). Activation of certain hydrolytic enzymes is observed in tissues of the liver, kidneys, heart and spleen: a rise in total activity (of arylsulphatase in the liver and acid catepsins in the spleen; hyaluronidase in the kidneys, beta-D-glucuronidase in the heart) and a change in the ratio of different forms with a simultaneous increase in the activity of free form (of hyaluronidase in the spleen, acid phosphatase in the heart and liver). Inhibition of alpha-D-glucosidase in the liver and beta-D-glucosidase in the spleen is also detected. A decrease in the activity of beta-D-glucuronidase in the spleen is pronounced in a significant decrease in the activity of each enzyme free form with no changes in the total activity.
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D001168:Arthritis / Q000201:enzymology*; D001169:Arthritis, Experimental / Q000201:enzymology*; D001192:Arylsulfatases / Q000378:metabolism; D002403:Cathepsins / Q000378:metabolism; D002462:Cell Membrane / Q000201:enzymology; D006026:Glycoside Hydrolases / Q000378:metabolism; D006867:Hydrolases / Q000378:metabolism*; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D051381:Rats; D013154:Spleen / Q000201:enzymology
D006867:Hydrolases; D000135:Acid Phosphatase; D001192:Arylsulfatases; D006026:Glycoside Hydrolases; D002403:Cathepsins
Gidroliticheskie fermenty tkaneĭ krys s adbiuvantnym artritom.