title: Cytotoxic activity of Aeromonas hydrophila.
abstract: Most strains of Aeromonas hydrophila tested demonstrated cytotoxic activity on several tissue-cultured cell lines. The cytotoxin is heat-labile, non-dialyzable, and immunologically distinct from that of Shigella dysenteriae and Clostridium perfringens. None of the aeromonas isolates was found to be enterotoxigenic by either tissue culture or rabbit ileal loop assays.
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism; D000333:Aeromonas / Q000502:physiology*; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D003603:Cytotoxins / Q000302:isolation & purification / Q000494:pharmacology*; D004789:Enzyme Activation / Q000187:drug effects; D006358:Hot Temperature; D013256:Steroids / Q000096:biosynthesis
chemical_list: D003603:Cytotoxins; D013256:Steroids; D000262:Adenylyl Cyclases