[Action of morphine and amidopyrine against a background of mineralocorticoid hormone and its antagonist].
The effect of morphine and amidopyrine, used against the background of a mineralocorticoid hormone or its antagonist excess (multiple administration of desoxycorticosteron acetate or verospiron), is mitigated. The pain-allaying effect of analgesics and their influence on the behavioral reactions are less marked in both models than it is in intact animals and their toxocity is down.
D000308:Adrenocortical Hyperfunction / Q000139:chemically induced; D000632:Aminopyrine / Q000494:pharmacology*; D000698:Analgesia; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D003900:Desoxycorticosterone / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D004347:Drug Interactions; D009020:Morphine / Q000494:pharmacology*; D051381:Rats; D013148:Spironolactone / Q000494:pharmacology*; D013997:Time Factors
D000632:Aminopyrine; D013148:Spironolactone; D003900:Desoxycorticosterone; D009020:Morphine
Deĭstvie morfina i amidopirina na fone mineralokortikoidnogo gormona i ego antagonista.