[Use of the "Steritest" apparatus for testing the sterility of antibiotic preparations].
The efficiency of determining microbial contamination of artificially infected preparations of 8 antibiotics in ampoules and bottles and erythromycin eye ointment with the use of apparatus "Steritest" and "Millipore" was compared. It was found that "Steritest" had a number of advantages as compared to "Millipore" because of elimination of operations for preparing the apparatus for the assay, which prevented contamination of the apparatus with microorganisms from the environment. The time required for the assay with the use of "Steritest" was 2 times shorter and the amount of the tioglycol medium was 2 times lower.
D000900:Anti-Bacterial Agents / Q000032:analysis*; D004340:Drug Contamination; D005602:France; D008567:Membranes, Artificial; D008851:Micropore Filters; D009883:Ophthalmic Solutions; D012996:Solutions; D013678:Technology, Pharmaceutical / Q000295:instrumentation*
D000900:Anti-Bacterial Agents; D008567:Membranes, Artificial; D009883:Ophthalmic Solutions; D012996:Solutions
Ispol'zovanie apparata "Steritest" dlia ispytaniia steril'nosti preparatov antibiotikov.