title: Second primaries in cases of cancer of the larynx.
abstract: The incidence of second primaries in 1,600 patients treated with radiotherapy for cancer of the larynx is reviewed. Carcinoma of the lung is the most frequent second primary with a significantly higher incidence in supraglottic laryngeal cancer. Because the follow-up of this irradiated population is limited it is not yet possible to estimate the risks of radiation-induced cancer in the entire life span following radiation treatment of cancer of the larynx.
mesh_terms: D002291:Carcinoma, Papillary / Q000453:epidemiology*; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology*; D005260:Female; D006258:Head and Neck Neoplasms / Q000453:epidemiology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000453:epidemiology* / Q000532:radiotherapy; D008175:Lung Neoplasms / Q000453:epidemiology; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology*; D013997:Time Factors