title: [Determination of the period of sex cell sensitivity of the chick embryo to the action of estradiol benzoate].
abstract: The sensitivity period of chick embryo sex cells to estradiol-benzoate was determined using injection of the hormone into eggs on days 5, 6, 7 or 8 of embryonal development. The hormone influence on the change or reproduction rate in 9 day old embryos was determined by thymidine autoradiography. The hormone injection on days 5, 6 and 7 causes an essential gonade reformation and increase of the proliferation rate of sex cells in genetically male embryos. The hormone injection on the 8th day did not change the sex cell reproduction rate but in some degree stimulated the reproduction of germinative epithelium of the left gonades in male embryos. A conculsion is made on the existence of a period of sensitivity in the sex cells to the effect of female sex hormone limited by 7 days of embryo developmnet.
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002642:Chick Embryo; D004958:Estradiol / Q000494:pharmacology*; D008297:Male; D013737:Testis / Q000166:cytology / Q000187:drug effects*; D013997:Time Factors
chemical_list: D004958:Estradiol
vernacular_title: Opredelenie perioda chuvstvitel'nosti polovykh kletok kurinogo émbriona k deĭstviiu éstradiol-benzoata.