Isolated Sertoli cells from immature rats produce 20alpha-hydroxy-pregn-4-en-3-one from progesterone and 3beta,20alpha-dihydroxy-5alpha-pregnane from pregnenolone.
D004092:20-alpha-Dihydroprogesterone / Q000096:biosynthesis*; D000818:Animals; D002250:Carbon Radioisotopes; D002849:Chromatography, Gas; D008297:Male; D011276:Pregnanediol / Q000096:biosynthesis*; D011284:Pregnenolone / Q000378:metabolism*; D011374:Progesterone / Q000031:analogs & derivatives* / Q000378:metabolism*; D051381:Rats; D012708:Sertoli Cells / Q000378:metabolism*
D002250:Carbon Radioisotopes; D004092:20-alpha-Dihydroprogesterone; D011374:Progesterone; D011284:Pregnenolone; D011276:Pregnanediol