title: In-111 transferrin labeling studied by perturbed angular correlations.
abstract: The technique of perturbed angular correlations (P.A.C.) was used to study transferrin labeled with radioactive indium. Three forms of the labeled system were studied: a) the In-111 was bound to transferrin with no iron present at either of the binding sites; b) the In-111 probe was used to label transferrin that was 33% saturated with iron; and c) the label was attached to saturated Fe-transferrin. The measured perturbation factors, G22(t), indicate that the three binding states are clearly differentiated. Cases (a) and (b) exhibit characteristic features of time-independent quadrupole interactions and the average quadrupole interaction frequencies, omegaq, were determined in these cases.
mesh_terms: D001665:Binding Sites; D007204:Indium; D007553:Isotope Labeling / Q000379:methods*; D011868:Radioisotopes; D013679:Technology, Radiologic; D013997:Time Factors; D014168:Transferrin
chemical_list: D011868:Radioisotopes; D014168:Transferrin; D007204:Indium