[Comparative pathomorphological study of the experimental action of carminomycin and rubomycin on the heart].
Comparative histological investigation of the toxic effect of carminomycin and rubomycin on the myocardium was carried out on mice BDF. It was found that the level of the morphological changes in the heart muscle depended on the antibiotic dose. The cardiotoxic effect of carminomycin was less pronounced than that of rubomycin.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000633:toxicity*; D002360:Carubicin / Q000633:toxicity*; D003630:Daunorubicin / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation / Q000187:drug effects; D006321:Heart / Q000187:drug effects*; D007928:Lethal Dose 50; D051379:Mice; D008815:Mice, Inbred Strains; D009206:Myocardium / Q000201:enzymology / Q000473:pathology*; D013997:Time Factors
D000903:Antibiotics, Antineoplastic; D002360:Carubicin; D003630:Daunorubicin
Sravnital'noe patomorfologicheskoe issledovanie deĭstviia na miokard karminomitsina i rubomitsina v éksperimente.