[Study of hydrolase activity of rat small intestine mucosa with vitamin A deficiency].
The activity of amylase, alkaline phosphatase and lipase in the pancreas, in the mucosa and on the surface of small intestine (turned out segments) was studied for elucidating the effect of vitamin A deficiency on the synthesis of the studied enzymes and their translocation to the surface of glycocalix cell membranes. The activity of amylase is established to increase in the homogenate of the pancreas, intestine mucosa and on the surface of cell membranes. The activity of alkaline phosphatase and lipase in the homogenate of small intestine mucosa and in the pancreas lowers. The results obtained evidence for a disturbance in the intestine digestive function with vitamin A deficiency, the may be connected with the damage of the mucosa membrane structures as well as with a disturbance in the biosynthesis of the protein playing a decisive role in formation of secretory products in cells.
D000469:Alkaline Phosphatase / Q000378:metabolism; D000681:Amylases / Q000378:metabolism; D000818:Animals; D006867:Hydrolases / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000201:enzymology*; D007421:Intestine, Small / Q000201:enzymology*; D008049:Lipase / Q000378:metabolism; D008297:Male; D010179:Pancreas / Q000201:enzymology; D051381:Rats; D014802:Vitamin A Deficiency / Q000201:enzymology*
D006867:Hydrolases; D008049:Lipase; D000469:Alkaline Phosphatase; D000681:Amylases
Izuchenie gidrolaznoĭ aktivnosti slezistoĭ obolochki tonkogo kischechinka krys pri nedostatochnosti vitamina A.