Morphologic sequelae to contrast medium deposits in the kidney. An experimental investigation in the rabbit.
Various doses of Pantopaque and Vascoray were injected percutaneously into the kidneys in 17 rabbits. Histologic examination of the kidneys at different time intervals following the injection demonstrated only slight injury to the renal parenchyma which could be related to the contrast media. Therefore, it seems reasonable to assume that the risk of causing renal damage by using Pantopaque in connection with renal cyst puncture is small.
D000818:Animals; D003287:Contrast Media / Q000009:adverse effects*; D006406:Hematoma / Q000139:chemically induced; D007267:Injections; D007462:Iodobenzenes / Q000009:adverse effects*; D007481:Iophendylate / Q000008:administration & dosage / Q000009:adverse effects*; D007482:Iothalamate Meglumine / Q000008:administration & dosage / Q000009:adverse effects*; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D007674:Kidney Diseases / Q000139:chemically induced* / Q000473:pathology; D011817:Rabbits
D003287:Contrast Media; D007462:Iodobenzenes; D007481:Iophendylate; D007482:Iothalamate Meglumine