title: [Differing results of direct and indirect solid phase radioimmunoassay for HBsAg in acute hepatitis (author's transl)].
abstract: In 54 patients suffering from acute viral hepatitis the indirect solid phase radioimmunoassay (ind-SPRIA) for HBsAg was positive in 9 cases the direct solid phase radioimmunoassay (d-SPRIA) being negative. In 2 further cases ind-SPRIA was positive during several weeks but d-SPRIA only once. AntiHBc could be detected in 9 of these patients. In 7 patients the usual decrease of the transaminase activity was followed by a second elevation with prolongation of disease. The unknown factor detected by ind-SPRIA suggests a special form of acute hepatitis.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006510:Hepatitis B Antibodies / Q000032:analysis; D006511:Hepatitis B Antigens / Q000032:analysis*; D006525:Hepatitis, Viral, Human / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D000637:Transaminases / Q000378:metabolism
chemical_list: D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens; D000637:Transaminases
vernacular_title: Unterschiedliches Ergebnis des direkten und indirekten Festphasenradioimmuntests zum Nachweis von HBsAg bei akuter Hepatitis.