Effects of mibolerone on conception, pregnancy, parturition, and offspring in the Beagle.
Mibolerone was administered to Beagle bitches at dose levels of 20 or 60 microgram/day, starting 1,3, or 6 days after the 1st breeding and continuing until the offspring were weaned. Adverse effects on conception, pregnancy, or parturition were not observed in the treated bitches. Female offspring were masculinized. There were no gross effects on the male offspring.
D000818:Animals; D001724:Birth Weight; D012734:Disorders of Sex Development / Q000139:chemically induced / Q000662:veterinary; D004283:Dog Diseases / Q000139:chemically induced; D004285:Dogs / Q000502:physiology*; D005260:Female; D005306:Fertilization / Q000187:drug effects*; D007743:Labor, Obstetric / Q000187:drug effects*; D008098:Litter Size; D008297:Male; D009277:Nandrolone / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000494:pharmacology; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*
D009277:Nandrolone