Reaction of DNA with alkylating agents. Quantitation of alkylation by ethylnitrosourea of oxygen and nitrogen sites on poly[dA-dT] including phosphotriester formation.
D000225:Adenine; D000478:Alkylation; D001665:Binding Sites; D003851:Deoxyribonucleases; D005038:Ethylnitrosourea; D005092:Exonucleases; D008274:Magnesium; D009584:Nitrogen; D009607:Nitrosourea Compounds; D010755:Organophosphates; D009943:Organophosphorus Compounds; D009994:Osmolar Concentration; D010100:Oxygen; D011067:Poly dA-dT; D011089:Polydeoxyribonucleotides; D012964:Sodium; D013941:Thymine
D009607:Nitrosourea Compounds; D010755:Organophosphates; D009943:Organophosphorus Compounds; D011089:Polydeoxyribonucleotides; D011067:Poly dA-dT; D012964:Sodium; D003851:Deoxyribonucleases; D005092:Exonucleases; D008274:Magnesium; D000225:Adenine; D009584:Nitrogen; D005038:Ethylnitrosourea; D013941:Thymine; D010100:Oxygen