Crystal induced arthritis: gout and pseudogout.
Intrasynovial deposits of monourate crystals in the presence of serum hyperuricaemia, and calcium pyrophosphate dihydrate (CPPD) crystals, are responsible for gout and pseudogout respectively. Identification of these by synovial fluid analysis is described. The clinical features, minimum investigations, history-taking, management and drug regimes of gout and pseudogout are discussed. Periodic review of the patient is stressed. Other intrasynovial crystals are briefly outlined.
D000208:Acute Disease; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001031:Apatites / Q000032:analysis; D001168:Arthritis / Q000175:diagnosis; D002126:Calcium Hydroxide / Q000032:analysis; D002131:Calcium Pyrophosphate / Q000032:analysis; D002784:Cholesterol / Q000032:analysis; D002805:Chondrocalcinosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003460:Crystallization; D005260:Female; D006073:Gout / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000601:surgery; D011859:Radiography; D013582:Synovial Fluid / Q000032:analysis; D014527:Uric Acid / Q000032:analysis
D000893:Anti-Inflammatory Agents; D001031:Apatites; D014527:Uric Acid; D002784:Cholesterol; D002126:Calcium Hydroxide; D002131:Calcium Pyrophosphate