Servo-controlled lumbar infusions: a clinical tool for the determination of CSF dynamics as a function of pressure.
The variable rate lumbar subarachnoid infusion technique allows rapid quantitative study of the cerebrospinal fluid (CSF) compartment. Numerous pressure plateaus are studied in a brief time period with a servo-controlled system. The test determines the difference between rates of CSF absorption and formation as a function of pressure. On-line computer data analysis increases experimental efficiency to guarantee statistical significance. Animal and patient data are presented in the report.
D000042:Absorption; D000293:Adolescent; D000328:Adult; D000818:Animals; D001825:Body Fluid Compartments; D002555:Cerebrospinal Fluid / Q000378:metabolism / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D003201:Computers; D004285:Dogs; D006801:Humans; D007223:Infant; D007263:Infusions, Parenteral / Q000295:instrumentation / Q000379:methods; D008161:Lumbosacral Region; D008365:Manometry / Q000295:instrumentation / Q000379:methods; D008875:Middle Aged; D011312:Pressure; D013346:Subarachnoid Space