title: Copper salts for growth stimulation and alleviation of aortic rupture losses in turkeys.
abstract: Approximately 4000 Large White, day-old turkey poults were used in a series of eight experiments to study the effects of dietary copper supplementation. The hens were grown to 15 or 16 weeks and toms to 24 weeks of age. Either copper as the oxide or sulfate (hydrate) at 120 ppm stimulated growth up to 10% with a concurrent reduction in feed requirement. Levels of 60 ppm were not adequate, whereas 240 ppm were not toxic. There was a greater response to copper in the presence of 4-nitrophenylarsonic acid (4-nitro) or with low protein diets. In two of the eight studies copper enhanced aortic elastin content. Incidence of aortic rupture was greater in the presence of 4-nitro and was reduced by one-half through copper supplementation. Liver copper was not altered by 60 or 120 ppm Cu; 240 ppm caused a significant increase.
mesh_terms: D000818:Animals; D001012:Aorta, Abdominal / Q000032:analysis; D001019:Aortic Rupture / Q000517:prevention & control / Q000662:veterinary*; D001152:Arsenicals / Q000494:pharmacology; D003300:Copper / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D004549:Elastin / Q000032:analysis; D005260:Female; D005840:Gentian Violet / Q000494:pharmacology; D006128:Growth / Q000187:drug effects; D007491:Ipronidazole / Q000494:pharmacology; D008099:Liver / Q000378:metabolism; D008297:Male; D009578:Nitrobenzenes / Q000494:pharmacology; D009761:Nystatin / Q000494:pharmacology; D011201:Poultry Diseases / Q000517:prevention & control*; D014422:Turkeys / Q000254:growth & development* / Q000378:metabolism
chemical_list: D001152:Arsenicals; D009578:Nitrobenzenes; D007491:Ipronidazole; D009761:Nystatin; D003300:Copper; D004549:Elastin; D005840:Gentian Violet