A low-sulfated chondroitin sulfate in rat blood: an acidic glycosaminoglycan with a high metabolic rate.
The rate of metabolism of low-sulfated chondroitin 4-sulfate, a predominant glycosaminoglycan in blood, has been studied by administering intraperitoneally radioactive hexosamine and/or sulfate to rats. The biological half-life of the material was estimated to be 10--12 h, suggesting that the metabolic process of blood low-sulfated chondroitin sulfate is different from that of glycosaminoglycans in the tissue.
D000818:Animals; D002807:Chondroitin / Q000031:analogs & derivatives*; D002809:Chondroitin Sulfates / Q000097:blood* / Q000652:urine; D005944:Glucosamine / Q000378:metabolism; D006025:Glycosaminoglycans / Q000097:blood* / Q000652:urine; D006207:Half-Life; D008297:Male; D051381:Rats; D013431:Sulfates / Q000378:metabolism
D006025:Glycosaminoglycans; D013431:Sulfates; D002807:Chondroitin; D002809:Chondroitin Sulfates; D005944:Glucosamine