Thallium intoxication treated with long-term hemodialysis, forced diuresis and Prussian blue.
A 56-year-old woman, who ingested 2 g of thallium sulfate, was successfully treated with long-term hemodialysis for 200 hours during ten days, combined with forced diuresis and Prussian blue. The effect of the artificial kidney dialysis was determined by repeated analysis of the thallium concentration in the dialysis bath and in blood samples. During the first 120 hours of hemodialysis, 143 mg of thallium was eliminated via the artificial kidney and 110 mg via the urinary tract. The present case of acute thallium intoxication is the first in which long-term hemodialysis has been used in the acute phase together with forced diuresis and Prussian blue. The data obtained are compared to those obtained from cases treated with hemodialysis in the past. It is concluded that treatment with hemodialysis should be considered as an important supplement to treatment with forced diuresis and Prussian blue in cases of thallium intoxication.
D000931:Antidotes / Q000627:therapeutic use*; D004396:Coloring Agents / Q000627:therapeutic use*; D004231:Diuresis; D005260:Female; D006801:Humans; D008875:Middle Aged; D006435:Renal Dialysis; D013793:Thallium / Q000506:poisoning*; D013997:Time Factors
D000931:Antidotes; D004396:Coloring Agents; D013793:Thallium