title: Nafcillin-associated granulocytopenia.
abstract: Three patients treated with nafcillin developed granulocytopenia. Only three other such cases have been reported. This complication is most likely due to a direct toxic effect on the bone marrow; markers for an immunologically mediated mechanism have not been found. Nafcillin-associated granulocytopenia usually occurs during the third week of therapy and remits spontaneously with prompt cessation of nafcillin administration.
mesh_terms: D000293:Adolescent; D000380:Agranulocytosis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009254:Nafcillin / Q000008:administration & dosage / Q000009:adverse effects*; D012075:Remission, Spontaneous; D013997:Time Factors
chemical_list: D009254:Nafcillin