Case report: chenodeoxycholic acid therapy of intrahepatic radiolucent gallstones in a patient with Caroli's syndrome.
A 28-year-old man with intrahepatic cystic dilatations of the biliary tree (Caroli's syndrome) which contained multiple radiolucent gallstones was treated with 1 g of chenodeoxycholic acid per day. He had undergone cholecystectomy 4 years and surgical exploration of the common bile duct with papillotomy 2 years prior to chenodeoxycholic acid therapy. While no decrease in the number of stones could be detected by retrograde cholangiography 2 years after papillotomy, most of the stones had disappeared after 2 years of treatment with chenodeoxycholic acid.
D000328:Adult; D001653:Bile Ducts, Intrahepatic; D001660:Biliary Tract Diseases / Q000150:complications; D002635:Chenodeoxycholic Acid / Q000627:therapeutic use*; D002758:Cholangiography; D002769:Cholelithiasis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D004108:Dilatation, Pathologic; D006801:Humans; D008107:Liver Diseases / Q000188:drug therapy*; D008297:Male; D013577:Syndrome
D002635:Chenodeoxycholic Acid