title: [Characteristics of the indicators of the blood coagulation and fibrinolysis systems in the pre-clinical stage of ischemic heart disease].
abstract: Signs of dysfunction of the coagulation system and fibrinolysis were determined in 45 healthy young individuals who had such risk factors in relation to ischemic heart disease as arterial hypertension, hypercholesterolemia, smoking, aggravated heredity, permanent emotional overstress, etc. These signs were manifested by a tendency to augmentation of blood coagulation and compensatory activation of fibrinolysis. Ischemic-type changes were detected on the ECG after a physical load. It is assumed that dysfunction of the coagulation system and fibrinolysis is an additional risk factor in relation to ischemic heart disease, while derangement of compensatory fibrinolysis tension with the subsequent tension of its components may lead to the development of coronary thrombosis.
mesh_terms: D000328:Adult; D000990:Antithrombin III / Q000032:analysis; D001777:Blood Coagulation; D003327:Coronary Disease / Q000097:blood* / Q000209:etiology; D005337:Fibrin / Q000032:analysis; D005338:Fibrin Fibrinogen Degradation Products / Q000652:urine; D005340:Fibrinogen / Q000032:analysis; D005342:Fibrinolysis; D006801:Humans; D008297:Male; D010960:Plasminogen Activators / Q000097:blood; D012306:Risk
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; D000990:Antithrombin III; D005337:Fibrin; D005340:Fibrinogen; D010960:Plasminogen Activators
vernacular_title: Kharakteristika pokazateleĭ sistemy svertyvaniia krovi i fibrinoliza v doklinicheskoĭ stadii ishemicheskoĭ bolezni serdtsa.