Urinary excretion of 3,3',5'-triiodothyronine (reverse T3).
A simple and sensitive radioimmunoassay for reverse T3 in urine using small Sephadex G25 fine columns is described. The recovery of rT3 added to urine was on average 101.0 +/- 4.2% (mean +/- SEM). Detection limit was 4 pg/column. Urine excretion of rT3 (mean +/- SD) was 72.0 +/- 32.1 ng/24 h in 61 healthy euthyroid subjects with a slight increase with age (P less than 0.05), 28.8 +/- 18.2 ng/24 h in 12 hypothyroid patients and 183.6 +/- 79.7 ng/24 in 25 hyperthyroid patients.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002850:Chromatography, Gel; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000652:urine; D007037:Hypothyroidism / Q000652:urine; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay / Q000379:methods; D014284:Triiodothyronine / Q000652:urine*; D014285:Triiodothyronine, Reverse / Q000652:urine*
D014284:Triiodothyronine; D014285:Triiodothyronine, Reverse