[Effect of estradiol and tocopherol on peroxidation of erythrocyte membrane lipids following ultraviolet irradiation].
The effect of the antioxidants estradiol and tocopherol on the lipid photoperoxidation in the erythrocyte membranes of rats under UV-irradiation was investigated. Both agents are shown to inhibit the release of potassium ions and hemoglobin provoked by UV-rays, estradiol activity being higher as compared to that of tocopherol. High activity of estradiol is due to the fact that this antioxidant does not lose its antiradical properties when its molecules are exposed to UV-irradiation.
D000818:Animals; D002463:Cell Membrane Permeability / Q000187:drug effects / Q000528:radiation effects; D004910:Erythrocyte Membrane / Q000187:drug effects* / Q000528:radiation effects; D004912:Erythrocytes / Q000187:drug effects*; D004958:Estradiol / Q000494:pharmacology*; D006454:Hemoglobins / Q000378:metabolism; D006461:Hemolysis / Q000187:drug effects; D011188:Potassium / Q000378:metabolism; D051381:Rats; D014466:Ultraviolet Rays; D014810:Vitamin E / Q000494:pharmacology*
D006454:Hemoglobins; D014810:Vitamin E; D004958:Estradiol; D011188:Potassium
Vliianie éstradiola i tokoferola na perekisnoe okislenie lipidov membran éritrotsitov pri ul'trafioletovom obluchenii.