[Experimental droperidol protection and treatment of pulmonary edema].
The authors carried out an experimental study of the protective and therapeutic effect of droperydol on 48 rabbits, with adrenaline lung edema. The results from the conducted studies showed that droperydol, administered both prophylacticaly and therapeuticaly, diminished significantly the gravity of lung edema and increased the percentage of survival up to 67.7% (in rats, treated therapeuticaly) and up to 100% (in the rats, treated prophylacticaly), while the survival did not surpass 20% in the control group. These results were better in comparison with the data, found earlier, indicating the effect of chlorasine, which manifested only protective action in rabbits with lung edema and worsened its course, when it was applied therapeuticaly.
D000818:Animals; D004329:Droperidol / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D004837:Epinephrine / Q000008:administration & dosage; D006439:Hemodynamics / Q000187:drug effects; D011654:Pulmonary Edema / Q000139:chemically induced / Q000188:drug therapy*; D011817:Rabbits
D004329:Droperidol; D004837:Epinephrine
Protektsiia i terapiia na belodroben otok s droperidol v eksperiment.