Electronic cell volume analysis of growth and rejection of EL-4 ascites tumor cells.
The in vivo growth of EL-4 ascites tumor cells in peritoneal cavities of syngeneic (C57BL/6) and allogeneic (DBA/2) mice was monitored by electronic volume analysis. In the growth of EL-4 cells in the C57BL/6 mice, daily decrease in electronic modal cell volume and labeling indices was observed. After day 7, the rejection of EL-4 cells in DBA/2 mice was indicated by increase in the percentage of small cytotoxic lymphocytes and decrease in the labeling indices of tumor cells.
D000818:Animals; D002452:Cell Count; D006084:Graft Rejection; D007942:Leukemia, Experimental / Q000276:immunology / Q000473:pathology*; D008214:Lymphocytes / Q000473:pathology; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009368:Neoplasm Transplantation; D014184:Transplantation, Homologous; D014185:Transplantation, Isogeneic