Synthesis of ring halogenated prostaglandins (1).
The synthesis of nine mono- and difluoro prostaglandins XIII, XV, XXIV, XXVII, XXXII, XXXVIII, XLV, LI and LIV, and two monochloro prostaglandins LVII and LXI, from appropriately protected derivatives of natural PGF2 is described.
D002713:Chlorine; D005461:Fluorine; D009682:Magnetic Resonance Spectroscopy; D008722:Methods; D011465:Prostaglandins, Synthetic / Q000138:chemical synthesis*
D011465:Prostaglandins, Synthetic; D005461:Fluorine; D002713:Chlorine