title: [Giant cell tumors of the sacrum (author's transl)].
abstract: In connection with our observations of three patients with giant-cell tumors of the sacrum a description of this disease is given reviewing the 51 cases which have been published world-wide. As other tumors of the sacrococcygeal region the giant-cell tumor has no significant symptoms which would allow a differential diagnosis. Pain in the sacral region often radiating to both legs is the predominant symptom. Surgical intervention is the treatment of choice. To obtain a complete excision of the tumor with minimal damage to nervous structures the abdominal, sacral or abdomino-sacral route is recommended by several authors. The prognosis is dubious because a total removal is usually not feasable, and there is a high risk of recurrence and malignant degeneration.
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005870:Giant Cell Tumors / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008722:Methods; D008875:Middle Aged; D012447:Sacrum; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000601:surgery
vernacular_title: Riesenzelltumoren des Sacrum.