title: [Study of the effectiveness and tolerance of Pevaryl 1 % milk in the treatment of mycoses of the external auditory meatus (author's transl)].
abstract: Otomycoses account for approximately 20 % of cases of otitis externa. Often unrecognised, they may be induced by various factors, in particular local antibiotic and corticosteroid therapy. The authors studied the effectiveness and tolerance of Econazole (1 % milk) in the treatment of otomycoses. In each of 30 cases, a bacteriological examination was made before and one week after treatment, the latter consisting of the insertion into the E.A.M. of a wick soaked in Econazole (1 % milk) every night. From a mycological standpoint, the fungus disappeared in all cases. Clinically, in relation to the criteria of assessment, a successful result was recorded in 28 cases out of 30. In 87 % of cases, cure was obtained in less than 2 weeks, and apart from a transient and brief subjective sensation of an increase in certain symptoms (17 %), tolerance was perfect. Econazole (1 % milk) would appear to be the drug of choice in the treatment of otomycoses of the E.A.M., being effective against the fungi usually responsible (Aspergillus niger, fumigatus, flavus, Candida albicans, krusei etc.), as well as having a bactericidal action against Gram + bacteria.
mesh_terms: D000328:Adult; D004464:Econazole / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D008297:Male; D009181:Mycoses / Q000188:drug therapy*; D010032:Otitis Externa / Q000188:drug therapy*
chemical_list: D007093:Imidazoles; D004464:Econazole
vernacular_title: Etude de l'efficacité et de la tolérance du Pévaryl lait 1 % dans le traitement des mycoses du conduit auditif externe.