[The effect of acute liver damage on inactivation of renin and aldosterone (author's transl)].
Plasma renin activity was measured in 5 surgical patients with hydatoid disease of the liver before and after partial hepatectomy. Plasma renin activity rose statistically significantly after surgical operation and remained virtually constant thereafter. This rise was accompanied by a statistically significant rise of plasma aldosterone while urinary excretion of aldo-18oxo-glucuronid remained unchanged. No change of urinary excretion of electrolytes was observed. It is concluded that besides stress after surgical operation decreased hepatic inactivation of renin and aldosterone were the main causes which led to elevation of plasma aldosterone concentration.
D000450:Aldosterone / Q000097:blood*; D004444:Echinococcosis, Hepatic / Q000601:surgery; D005965:Glucuronates / Q000652:urine; D006801:Humans; D008099:Liver / Q000601:surgery*; D012083:Renin / Q000097:blood*
D005965:Glucuronates; D000450:Aldosterone; D012083:Renin
Der Einfluss akuter Leberschädigung auf die Inaktivierung von Renin und Aldosteron.