[Cardiocirculatory arrest due to hyperkalaemia following i.v. Imbretil for muscular relaxation (author's transl)].
The muscle relaxant Imbretil was investigated in 10 patients for initiating anaesthesia and for a prolonged artificial ventilation. In 50% of the patients a rather quick and drastic rise of the serum potassium-level was found. A cardiac arrest occurred in one patient due to a hyperkalaemia but fortunately was reversible. Consequently we do not use Imbretil in our Hospital anymore. Today better and less dangerous drugs are available instead--Imbretil must be placed as an obsolete drug.
D000759:Adjuvants, Anesthesia; D002217:Carbachol / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000494:pharmacology; D006323:Heart Arrest / Q000139:chemically induced*; D006801:Humans; D006947:Hyperkalemia / Q000139:chemically induced*; D009467:Neuromuscular Depolarizing Agents / Q000009:adverse effects* / Q000494:pharmacology
D000759:Adjuvants, Anesthesia; D009467:Neuromuscular Depolarizing Agents; D002217:Carbachol
Herz- und Kreislaufstillstand durch Hyperkaliämie nach Gabe des Muskelrelaxans Imbretil.