Neurobiological vulnerability to low-dose amphetamine psychosis.
The authors present a case to illustrate a model of drug-induced psychosis wherein the drug acts as if it fits with some neurobiological predisposition in the patient. Patients with a good interpersonal developmental history but extreme sensitivity to a psychotomimetic drug may provide a model for neurobiological vulnerability to psychosis.
D000328:Adult; D003913:Dextroamphetamine / Q000008:administration & dosage* / Q000009:adverse effects; D004198:Disease Susceptibility; D004298:Dopamine / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008954:Models, Biological; D011605:Psychoses, Substance-Induced / Q000209:etiology* / Q000503:physiopathology
D003913:Dextroamphetamine; D004298:Dopamine