A rapid direct determination of cadmium in blood by anodic stripping voltammetry.
This paper describes a rapid, sensitive anodic stripping voltammetry (ASV) method for measuring quantities of cadmium in blood. An advantage of this method is the minimal sample preparation required, using a metal-exchange reagent. A sensitivity of 4 nmol/l can be obtained. The results correlate with those obtained by atomic absorption spectroscopy. Within-run, the coefficient of variation (CV) was 8.9% at a cadmium concentration of 32 nmol/l. Between run CV was 5.4% at 37 nmol/l. The reference interval for blood cadmium concentration was 5-60 nmol/l for non-smokers and 5-85 nmol/l for cigarette-smokers. This method of cadmium analysis shows that ASV is a rapid, sensitive method for determination of blood cadmium in the normal range.
D000328:Adult; D000368:Aged; D002104:Cadmium / Q000032:analysis / Q000097:blood*; D006801:Humans; D007202:Indicators and Reagents; D008670:Metals; D008722:Methods; D008875:Middle Aged; D012907:Smoking
D007202:Indicators and Reagents; D008670:Metals; D002104:Cadmium