Induction of electrical excitability in crustacean muscle by 4-cyclopentene-1,3-dione.
4-Cyclopentene-1,3-dione induces electrical activity in inexcitable crustacean muscle. This effect is blocked by previous treatment with p-chloromercuribenzoic acid. These results suggest that crustacean muscle becomes excitable when certain -CH2-SH side chains are converted to thioethers having carbonyl groups.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002729:Chloromercuribenzoates / Q000494:pharmacology; D003445:Crustacea; D003517:Cyclopentanes / Q000494:pharmacology*; D009132:Muscles / Q000187:drug effects* / Q000502:physiology; D013329:Structure-Activity Relationship
D002729:Chloromercuribenzoates; D003517:Cyclopentanes; C017848:4-cyclopentene-1,3-dione