title: Methadone maintenance: an assessment of potential fluctuations in behavior between doses.
abstract: Thirty methadone maintenance outpatients were measured 1 and 25 hours after ingestion of methadone on auditory threshold, distance perception, simple and differential reaction time, time perception, attention span, and short-term memory. The results revealed a small but statistically significant difference between the two tests for distance perception. In addition, treatment interacted with preparatory interval on differential reaction time and with sex on attention span.
mesh_terms: D000293:Adolescent; D000328:Adult; D001288:Attention / Q000187:drug effects; D001309:Auditory Threshold / Q000187:drug effects; D001519:Behavior / Q000187:drug effects*; D004215:Distance Perception / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects; D008691:Methadone / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008875:Middle Aged; D011930:Reaction Time / Q000187:drug effects; D019966:Substance-Related Disorders / Q000523:psychology / Q000534:rehabilitation*; D013997:Time Factors; D013998:Time Perception / Q000187:drug effects
chemical_list: D008691:Methadone