Relative genealogic incidence of certain "civilization diseases" in a geriatric population versus pregeriatric groups.
In a prevalence epidemiologic study conducted in a characteristic submontane area in North Bohemia, the genealogic incidence of myocardial infarction, sudden brain vascular episodes, and malignant tumors was studied in a representative sample of persons aged 70 to 105 years. The incidence was then compared with that in two other samples: 1) men under age 40 with a history of transmural myocardial infarction, and 2) both men and women aged 40--60 who had a stroke. The statistical evaluation was performed according to accepted international criteria (WHO). A significantly lower genealogic incidence of myocardial infarction and sudden brain vascular episodes was found in the geriatric subjects (70--105 years old) who had symptoms of so-called physiologic aging, as compared with the incidence in the younger subjects who had symptoms of so-called pathologic aging. The difference was less clear-cut with respect to the genealogic incidence of malignant tumors.
D000328:Adult; D000367:Age Factors; D000368:Aged; D002561:Cerebrovascular Disorders / Q000453:epidemiology / Q000235:genetics*; D003604:Czechoslovakia; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology / Q000235:genetics*; D009369:Neoplasms / Q000453:epidemiology / Q000235:genetics*