Immunodeficiency associated with laevocardia, bronchiectasis, and paranasal sinus anomalies.
In a case of laevocardia, bronchiectasis, and paranasal sinus abnormalities, assessment on 2 occasions showed the presence of moderate immunodeficiency. Serum concentrations of IgG and IgM were low, and serum and salivary IgA was not detected. T-lymphocytes were reduced in number and cell-mediated immunity in vivo and in vitro was impaired. Opsonisation, complement system, and neutrophil functions were normal.
D001987:Bronchiectasis / Q000150:complications*; D002648:Child; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications*; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications*; D007979:Levocardia / Q000150:complications*; D010256:Paranasal Sinuses / Q000002:abnormalities*