Synthesis of some 2.5-disubstituted anilino-3.6-dichloro-1.4-benzoquinones as antimicrobial agents.
The potent antimicrobial properties of several chloroquinones prompted the synthesis of nineteen new 2.5-disubstituted anilino-3.6-dichloro-1.4-benzoquinone derivatives by reacting 2.5-dichloro-p-benzoquinone with many of the official antimicrobial sulphonamides and other related amines. Testing of six representative samples for their antimicrobial activity revealed good inhibitory results on the growth of five microorganisms.
D000814:Aniline Compounds / Q000138:chemical synthesis / Q000494:pharmacology; D000900:Anti-Bacterial Agents; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D011809:Quinones / Q000138:chemical synthesis* / Q000494:pharmacology
D000814:Aniline Compounds; D000900:Anti-Bacterial Agents; D011809:Quinones