[Comparative analytical study of the effects of psoralens in vitiligo (findings in 70 patients) (author's transl)].
70 patients with vitiligo were divided into two groups. --one group of 40 patients: treated with trioxsalen and sun rays; --one group of 30 patients: treated with methoxsalen and sun rays. Both the first and the second drug stopped the extension almost similarity (87.5 p. 100 positive results for the first group and 86.6 p. 100 for the second one). For the first group the action on the repigmentation was more important but the latent period was longer. Neither group showed side effects worth mentioning. The factors that influence favourably vitiligo and improve the evolution are: --the situation on uncovered parts of the body; --the length of treatment; --the promptness of institution of treatment; --the necessity of a maintenance treatment; --the appearance of erythema which is necessary for repigmentation.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004341:Drug Evaluation; D005260:Female; D011564:Furocoumarins / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008730:Methoxsalen / Q000627:therapeutic use*; D008875:Middle Aged; D010778:Photochemotherapy; D013997:Time Factors; D014307:Trioxsalen / Q000627:therapeutic use*; D014467:Ultraviolet Therapy; D014820:Vitiligo / Q000188:drug therapy*
D011564:Furocoumarins; D008730:Methoxsalen; D014307:Trioxsalen
Etude analytique et comparative de l'action des psoralènes dans le vitiligo (étude sur 70 cas).