title: The immunoglobulin allotypes (Gm and Km) of twelve Indian tribes of Central and South America.
abstract: The Gm and Km immunoglobulin allotypes are presented, for the first time, for six South American Indian tribes (Baniwa, Kanamari, Kraho, Makiritare, Panoa, and Ticuna) and one Central American tribe (Guaymi). Additional allotype information is presented for five previously reported South American tribes (Cayapo, Piaroa, Trio, Xavante and Yanomama). The distributions of the Gm and Km allotypes among all the tribal populations tested to date are reviewed and evidence is presented for the presence of a north (high)-south(low) cline in Km frequency. The wave theory of the populating of the South American continent was tested by an examination of the distribution of six alleles (Gmax;g, Gma;b0,3,t,Dia,Rx,TFDChi, and 6PGDC), absent in some populations but with polymorphic proportions in others. The present, limited, data failed to confirm the theory.
mesh_terms: D000483:Alleles; D044466:Asian People; D005787:Gene Frequency; D005788:Gene Pool; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000235:genetics*; D007197:Indians, Central American; D007199:Indians, South American; D010641:Phenotype
chemical_list: D007126:Immunoglobulin Allotypes