Acetaminophen poisoning.
A case of suspected acetaminophen poisoning is reported in a child who ingested 19 gm of acetaminophen over a seven-day period. She exhibited evidence of severe renal and hepatic damage which resolved with supportive therapy. Serum levels of acetaminophen were not in the toxic range; hence, proof of the etiology was not possible. It is probable that a delay in suspecting acetaminophen toxicity allowed time for the serum acetaminophen level to return to normal. Acetaminophen is a safe drug when used properly, but overdosage can cause severe toxicity. With increased use in this country, increasing episodes of overdosages should be anticipated. Blood levels should be obtained early in acutely ill patients when acetaminophen toxicity is suspected.
D000082:Acetaminophen / Q000097:blood / Q000506:poisoning*; D058186:Acute Kidney Injury / Q000139:chemically induced; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D007668:Kidney / Q000187:drug effects; D008099:Liver / Q000187:drug effects
D000082:Acetaminophen