Changes in the relative amount of surface antigens on the living cells after treatment with insoluble protease derivatives.
Relative amount of surface antigen was compared on L 1210 leukaemia cells treated with soluble or insoluble derivatives of trypsin and papain. Trypsin or trypsin insoluble derivative do not change the amount of antigen significantly as compared with control. However, papain insoluble derivative decrease the relative amount of antigen within 45 min to the value of 0.43 or 0.55 respectively as compared with the control specimen.
D000951:Antigens, Neoplasm / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis*; D002460:Cell Line; D003601:Cytotoxicity Tests, Immunologic; D003851:Deoxyribonucleases / Q000494:pharmacology; D007945:Leukemia, Lymphoid; D010206:Papain / Q000494:pharmacology*; D012995:Solubility; D014357:Trypsin / Q000494:pharmacology*
D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D003851:Deoxyribonucleases; D014357:Trypsin; D010206:Papain