The mechanism of the Miochol lens opacity.
We studied the reversible cataractogenic effect of Miochol on rabbits' lenses. The experiments demonstrated that the lens opacities developing after the intracameral injection of Miochol were caused by the hypertonicity of the solution and not by a biochemical effect of the acetylcholine.
D000109:Acetylcholine / Q000009:adverse effects*; D000818:Animals; D002386:Cataract / Q000139:chemically induced*; D006982:Hypertonic Solutions / Q000009:adverse effects*; D008353:Mannitol / Q000009:adverse effects*; D009995:Osmosis; D011817:Rabbits
D006982:Hypertonic Solutions; D008353:Mannitol; D000109:Acetylcholine