Motor nerve conduction velocity in experimental portal-systemic shunting. Preliminary communication.
The influence of portal-systemic shunting on motor nerve conduction velocity (MCV) was analyzed in rats with portacaval shunts. At 3 and 8 weeks after the shunting there was a marked but transient fall in MCV. At 16 weeks the MCV had almost normalized, despite sustained portal-systemic shunting. The results favour hepatocellular failure as the more important pathophysiological mechanism in hepatic neuropathy.
D000818:Animals; D007511:Ischemia / Q000503:physiopathology; D008297:Male; D009046:Motor Neurons / Q000502:physiology* / Q000503:physiopathology; D009431:Neural Conduction; D011167:Portacaval Shunt, Surgical; D051381:Rats; D013623:Tail / Q000098:blood supply / Q000294:innervation