Renal necrosis, glutathione depletion, and covalent binding after acetaminophen.
D000082:Acetaminophen / Q000378:metabolism / Q000633:toxicity*; D000818:Animals; D002712:Chlorides / Q000494:pharmacology; D003035:Cobalt / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005978:Glutathione / Q000378:metabolism; D066298:In Vitro Techniques; D007668:Kidney / Q000187:drug effects*; D007700:Kinetics; D008099:Liver / Q000187:drug effects*; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D008861:Microsomes / Q000187:drug effects; D011485:Protein Binding; D051381:Rats
D002712:Chlorides; D000082:Acetaminophen; D003035:Cobalt; D008748:Methylcholanthrene; D005978:Glutathione