Hypomagnesaemic hypocalcaemia with hypokalaemia caused by treatment with high dose gentamicin.
A 12-year-old boy developed renal wasting of magnesium, calcium, and potassium, with secondary hypomagnesaemia, hypocalcaemia, and hypokalaaemia (without hyperaldosteronism) after treatment with 14 400 mg gentamicin over 4 months. Gentamicin should not be given for prolonged courses if less toxic antibiotics are suitable. If it used, plasma magnesium, calcium, and potassium levels should be monitored during and after treatment.
D002648:Child; D004334:Drug Administration Schedule; D005839:Gentamicins / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D006996:Hypocalcemia / Q000139:chemically induced*; D007008:Hypokalemia / Q000139:chemically induced*; D008275:Magnesium Deficiency / Q000139:chemically induced*; D008297:Male
D005839:Gentamicins