[Production of a photo-sensitive lipid antibiotic by the marine diatom Chaetoceros lauderi (Ralfs) (author's transl)].
A lipid antibiotic was extracted from whole cells of the marine diatom Chaetoceros lauderi (Ralfs) and roughly identified as an unsaturated fatty acid by thin layer chromatography. A number of Gram-positive terrestrial bacteria and several Gram-negative marine bacilli were sensitive to this antibiotic, whereas Gram-negative enteric bacteria were resistant. Solar irradiation led to its partial disappearance and to the production of more polar antibiotics with a stronger antibacterial activity. This observation is compared to similar data culled from literature, and its significance in a natural environment is discussed.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000494:pharmacology / Q000528:radiation effects; D001419:Bacteria / Q000187:drug effects; D002855:Chromatography, Thin Layer; D056890:Eukaryota / Q000378:metabolism*; D005231:Fatty Acids, Unsaturated / Q000096:biosynthesis* / Q000494:pharmacology / Q000528:radiation effects; D008027:Light; D012623:Seawater; D013045:Species Specificity; D014871:Water Microbiology
D000900:Anti-Bacterial Agents; D005231:Fatty Acids, Unsaturated
Production d'un antibiotique lipidique photo-sensible par la diatomée marine Chaetoceros lauderi (Ralfs).