title: The effect of diuredosan on Echinococcus granulosus and Taenia hydatigena infections in dogs.
abstract: Diuredosan has been tested against Echinococcus granulosus and Taenia hydatigena infections in dogs. The drug showed significant activity against T hydatigena, but there was no significant dose response curve against E granulosus in this trial. Two treatments at 50 mg/kg or 100 mg/kg, however, reduced the number of dogs infected with hydatid worms. Worms were still present in some dogs after three treatments at 50 mg/kg. Vomiting and diarrhoea were relatively common sequelae at and above 50 mg/kg.
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004443:Echinococcosis / Q000188:drug therapy / Q000662:veterinary*; D005260:Female; D008297:Male; D009943:Organophosphorus Compounds / Q000627:therapeutic use*; D010671:Phenylurea Compounds / Q000627:therapeutic use; D013622:Taeniasis / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D000871:Anthelmintics; D009943:Organophosphorus Compounds; D010671:Phenylurea Compounds; C012545:uredofos