Juxtaglomerular cell tumor.
A 15-year-old female with primary reninism presented with benign hypertension, normokalemia, normal aortagram and normal intravenous pyelogram. The diagnosis was suggested only by a remarkably elevated plasma renin activity (PRA). Selective catheterization of renal vein branches was necessary to make the diagnosis of a tumor. A local resection of the tumor resulted in normalization of blood pressure and PRA. Prior to the definitive surgery, oral propranolol was effective in lowering PRA and blood pressure.
D000293:Adolescent; D001794:Blood Pressure; D003937:Diagnosis, Differential; D005260:Female; D006393:Hemangiopericytoma / Q000473:pathology*; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007606:Juxtaglomerular Apparatus; D007680:Kidney Neoplasms / Q000473:pathology*; D012083:Renin / Q000097:blood
D012083:Renin