A clinical study of slow-releasing artificial tears.
The slow-releasing artificial tear (SR-AT) is a soluble polymer in solid form. Placed in the inferior cul-de-sac and allowed to dissolve, it is used to treat dry-eye patients. The SR-AT was studied in two phases. The short-term cross-over study of 40 patients was completed in October 1976. The long-term open study is still in progress. Of 37 patients who started the long-term study, 18 are still using the inserts-a study retention of 49%.
D002482:Cellulose / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002648:Child; D003692:Delayed-Action Preparations; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007637:Keratoconjunctivitis / Q000188:drug therapy*; D008297:Male; D008747:Methylcellulose / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000188:drug therapy; D013262:Stevens-Johnson Syndrome / Q000150:complications; D014985:Xerophthalmia / Q000188:drug therapy*
D003692:Delayed-Action Preparations; D002482:Cellulose; D008747:Methylcellulose