Spontaneous and provoked coronary artery spasm: are they the same?
A 44-yr-old man suffering fro exertional, emotional and spontaneous angina underwent coronary arteriography. During the examination he had a spontaneous attack of angina with ST elevation in the anterior leads. Injection of a contrast medium in the left coronary artery during pain showed marked spasm with anterior descending artery occlusion. The spasm was quickly relieved by nitroglycerin. Intravenous administration of 0.4 mg of ergonovine maleate reproduced the anginal episode with pain, ST elevation in the anterior leads and coronarographic patterns of a spasm occluding the anterior descending artery at the same level. After nitroglycerin, the pain disappeared and the electrocardiographic and coronarographic findings returned to basal conditions.
D000328:Adult; D000787:Angina Pectoris / Q000139:chemically induced / Q000175:diagnosis; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000187:drug effects*; D003327:Coronary Disease / Q000139:chemically induced / Q000000981:diagnostic imaging*; D003331:Coronary Vessels / Q000187:drug effects; D004562:Electrocardiography; D004874:Ergonovine / Q000031:analogs & derivatives / Q000494:pharmacology*; D006801:Humans; D008297:Male
D004874:Ergonovine