title: Synthesis of benzimidazole derivatives with potential antispasmodic activity.
abstract: Some new esters and amides of benzimidazole-1-acetic acid which contain different cationic heads were prepared as atropine substitutes. Preliminary pharmacological testing showed that the prepared compounds possess atropine-like activity.
mesh_terms: D000818:Animals; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D008722:Methods; D009119:Muscle Contraction / Q000187:drug effects; D010276:Parasympatholytics
chemical_list: D001562:Benzimidazoles; D010276:Parasympatholytics