A needle biopsy would be quickest.
A case of a benign intrathoracic thyroid adenoma which was biopsied percutaneously is described. Except for a routine posterior-anterior (PA) and lateral chest X-ray examination, no preliminary investigations were performed. This resulted in several unnecessary procedures.
D000236:Adenoma / Q000175:diagnosis* / Q000473:pathology; D001707:Biopsy, Needle; D006801:Humans; D008297:Male; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology