Molecular structure of a double helical DNA fragment intercalator complex between deoxy CpG and a terpyridine platinum compound.
The crystal structure of a complex containing deoxy CpG and a terpyridine platinum compound (TPH) shows a DNA double helical fragment with TPH intercalated between two Watson-Crick GC base pairs. The DNA unwinding angle is 23 degrees and the pucker of the deoxyribose rings differ at the 3' and 5' ends.
D000166:Acridines; D004247:DNA; D004996:Ethidium; D006860:Hydrogen Bonding; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides; D009841:Oligonucleotides; D009843:Oligoribonucleotides; D009944:Organoplatinum Compounds; D014961:X-Ray Diffraction
D000166:Acridines; D009838:Oligodeoxyribonucleotides; D009841:Oligonucleotides; D009843:Oligoribonucleotides; D009944:Organoplatinum Compounds; D004247:DNA; D004996:Ethidium