title: Synthesis and antiviral and enzymatic studies of certain 3-deazaguanines and their imidazolecarboxamide precursors.
mesh_terms: D000265:Adenylosuccinate Synthase / Q000037:antagonists & inhibitors; D000818:Animals; D000890:Anti-Infective Agents / Q000138:chemical synthesis; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000627:therapeutic use; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism; D002478:Cells, Cultured; D003588:Cytopathogenic Effect, Viral / Q000187:drug effects; D006147:Guanine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D007168:IMP Dehydrogenase / Q000037:antagonists & inhibitors; D007093:Imidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D008297:Male; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000188:drug therapy; D011685:Purine Nucleotides / Q000096:biosynthesis*; D012254:Ribavirin / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D000998:Antiviral Agents; D007093:Imidazoles; D011685:Purine Nucleotides; D012254:Ribavirin; D006147:Guanine; D007168:IMP Dehydrogenase; D000265:Adenylosuccinate Synthase