Mediastinal rhabdomyoma.
An 80-year-old black male with gastric adenocarcinoma, liver metastases, and parathyroid adenomas also had a rhabdomyoma of the anterior-superior mediastinum. This appears to be the first reported case of mediastinal rhabdomyoma in the literature. The ultrastructural demonstration of haphazardly arranged myofilaments with prominent Z bands and the absence of demosomes indicates that it is of extra-cardiac type. The probable origin of this tumor from the myoid cells of the thymus is discussed.
D000230:Adenocarcinoma / Q000473:pathology; D000236:Adenoma / Q000473:pathology; D000368:Aged; D006338:Heart Neoplasms / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000196:embryology / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009210:Myofibrils / Q000648:ultrastructure; D009362:Neoplasm Metastasis; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D010282:Parathyroid Neoplasms / Q000473:pathology; D012207:Rhabdomyoma / Q000196:embryology / Q000648:ultrastructure*; D013274:Stomach Neoplasms / Q000473:pathology; D013950:Thymus Gland / Q000196:embryology