The effect of phentolamine on intra-Hisian conduction.
A His bundle electrogram was obtained in a 70 year old male with syncopal episodes. A split bundle of His deflection was recorded. After the intravenous administration of phentolamine, a marked shortening of the H-H' interval was observed. This signifies an improvement in conduction at the bundle of His level.
D000200:Action Potentials / Q000187:drug effects; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D002036:Bundle of His / Q000187:drug effects* / Q000503:physiopathology; D002037:Bundle-Branch Block / Q000188:drug therapy / Q000503:physiopathology; D002304:Cardiac Pacing, Artificial; D004562:Electrocardiography; D006329:Heart Conduction System / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D010646:Phentolamine / Q000627:therapeutic use*; D013575:Syncope / Q000188:drug therapy / Q000503:physiopathology
D010646:Phentolamine