The effects on thermoregulation of intracerebroventricular injections of L-aspartic acid in the sheep.
L-Aspartic acid was injected into a lateral cerebral ventricle of the sheep at ambient temperatures between 0 degrees and 40 degrees C. Doses of 100 or 500 nmoles-kg-1 caused a rise in heat production and/or a decrease in heat loss; rectal temperature rose. Atropine sulphate attenuated or prevented these effects.
D000818:Animals; D001224:Aspartic Acid / Q000008:administration & dosage / Q000494:pharmacology*; D001833:Body Temperature Regulation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D007276:Injections, Intraventricular; D008297:Male; D012756:Sheep / Q000502:physiology*; D013696:Temperature; D013997:Time Factors
D001224:Aspartic Acid