Lack of effect of bromocriptine on serum levels of calcium in the rat.
1. The effect of bromocriptine (a prolactin suppressant drug) on the serum levels of calcium was studied in the male rat. The drug was administered subcutaneously at a dosage of 100 microgram per 100 g body weight three times per day. 2. Chronic treatment with bromocriptine had no significant effect on the serum calcium levels. It appears that neither bromocroptine per se nor normal circulating prolactin levels exert any significant influence on blood calcium homeostasis.
D000818:Animals; D001971:Bromocriptine / Q000008:administration & dosage / Q000494:pharmacology*; D002118:Calcium / Q000097:blood*; D004305:Dose-Response Relationship, Drug; D007279:Injections, Subcutaneous; D008297:Male; D051381:Rats; D013997:Time Factors
D001971:Bromocriptine; D002118:Calcium