Sarcoma arising in oligodendroglioma of the brain: a case with intramedullary and subarachnoid spinal metastases.
A case of sarcoma arising in a left temporal oligodendroglioma is described in a 39-year-old male. The postoperative evolution was marked by a paraplegia linked to medullary and subarachnoid metastases. Then a relapse of the cerebral tumor occurred, and the patient died 6 months after the onset of the symptoms. Histologically, the mesenchymal component appeared fibrosarcomatous and angiosarcomatous. Those facts argue in favor of the histogenic hypotheses put forward in exceptional cases previously described, according to which the sarcoma develops from vascular elements of the glioma.
D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D008526:Medulla Oblongata; D009362:Neoplasm Metastasis / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009837:Oligodendroglioma / Q000473:pathology*; D012509:Sarcoma / Q000473:pathology*; D013120:Spinal Cord Neoplasms / Q000473:pathology; D013346:Subarachnoid Space