Resistance of mice to secondary infection with Schistosoma mansoni. I. Comparison of bisexual and unisexual initial infections.
Mice receiving a unisexual primary infection with either sex of Schistosoma mansoni did not develop detectable resistance to reinfection. In contrast, mice receiving a bisexual primary infection developed a high degree of resistance. The number of adult worms developing from the challenge infection was reduced, relative to controls, by 72--100% at challenge times of 6 weeks or greater.
D000818:Animals; D001700:Biomphalaria / Q000469:parasitology; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D012550:Schistosoma mansoni / Q000254:growth & development / Q000276:immunology*; D012552:Schistosomiasis / Q000276:immunology* / Q000469:parasitology; D012737:Sex Factors