Measurement of plasma nortriptyline concentrations: radioimmunoassay and gas-chromatography compared.
We compared measurement of plasma nortriptyline by a recently developed radioimmunoassay technique with values obtained by traditional gas chromatography. The coefficient of correlation (r) was 0.98 for 84 samples from 21 controlled patients; for a separate series of 45 samples from 34 patients who were receiving in addition other medication, r was 0.96. Use of radioimmunoassay in the routine determination of plasma nortriptyline concentration is discussed.
D002849:Chromatography, Gas; D006801:Humans; D009661:Nortriptyline / Q000097:blood*; D011863:Radioimmunoassay
D009661:Nortriptyline