Erythrocyte-Zn-protoporphyrin as an indicator of lead exposure.
Measurement of erythrocte-Zn-protoporphyrin with a haematofluorimeter on blood samples from eighty-four lead-exposed individuals has been compared with a fluorimetric determination of the extracted porphyrins. The results agreed well, and the interference from bilirubin and unchelated protoporphyrin was low. An exponential increase in erythrocyte protoporphyrin and a linear decrease in blood haemoglobin with increased blood lead was found in seventy-nine males with occupational lead exposure. The haematofluorimeter is recommended as a useful tool in screening for lead poisoning.
D001663:Bilirubin / Q000097:blood; D004781:Environmental Exposure; D004912:Erythrocytes / Q000032:analysis*; D005260:Female; D005470:Fluorometry / Q000295:instrumentation; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007854:Lead / Q000097:blood; D007855:Lead Poisoning / Q000097:blood*; D008297:Male; D011166:Porphyrins / Q000097:blood*; D011524:Protoporphyrins / Q000097:blood*; D015032:Zinc / Q000097:blood*
D006454:Hemoglobins; D011166:Porphyrins; D011524:Protoporphyrins; D007854:Lead; D015032:Zinc; D001663:Bilirubin