title: Biochemical mechanisms causing tick resistance.
abstract: Three general biochemical mechanisms can cause ticks to be resistant to acaricides: an alteration in the properties of the site of action, a change in the rate of transportation and a change in the rate of metabolism. The first mechanism enables increased concentrations of acaricide at the site of action to be tolerated, while the last two mechanisms result in a decreased concentration and/or persistence of the acaricide at the site of action. These mechanisms are discussed in detail with reference to a range or acaricides, particular emphasis being given to blue tick strains occurring in Southern Africa.
mesh_terms: D000818:Animals; D001152:Arsenicals / Q000378:metabolism; D002219:Carbamates; D007305:Insecticide Resistance; D007306:Insecticides / Q000378:metabolism; D009943:Organophosphorus Compounds; D010944:Plants; D013019:South Africa; D013987:Ticks / Q000378:metabolism*
chemical_list: D001152:Arsenicals; D002219:Carbamates; D007306:Insecticides; D009943:Organophosphorus Compounds