[UDPG pyrophosphorylase and phosphoglucomutase activity in the liver of rats with alloxan diabetes].
The UDPH-pyrophosphatase and phosphomurase activity was determined in the liver homogenates of rats with manifest alloxan diabetes. In comparison with control animals, there was a statistically significant reduction of UDPH-pyrophosphorylase and phosphoglucomutase activity (by 29 and 33%, respectively) in diabetic rats. Decreased activity of the mentioned enzymes in the liver of rats with alloxan diabetes pointed to their participation in reduction of glycogen synthesis in the liver occurring in this disease.
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology*; D004789:Enzyme Activation; D066298:In Vitro Techniques; D008099:Liver / Q000201:enzymology*; D008112:Liver Glycogen / Q000378:metabolism; D009713:Nucleotidyltransferases / Q000378:metabolism*; D010733:Phosphoglucomutase / Q000378:metabolism*; D051381:Rats; D013997:Time Factors; D005957:UTP-Glucose-1-Phosphate Uridylyltransferase / Q000378:metabolism*
D008112:Liver Glycogen; D009713:Nucleotidyltransferases; D005957:UTP-Glucose-1-Phosphate Uridylyltransferase; D010733:Phosphoglucomutase
Aktivnost' UDFG-prifosforilazy i fosfogliukomutazy v pecheni krys pri alloksanovom diabete.