[Effect of biogenic amines on phosphorolysis and gamma-amylolysis of glycogen in the cardiac muscle of rats under anesthesia].
Adrenaline, poradrenaline, serotonin, triptamine and 3-hydroxytyramine activated glycogen phosphorolysis in heart of nonanesthetized rats due to increase in the phosphorylase A activity. Anesthesia with nembutal and ether prevented the stimulating effect of biogenic amines (excluding serotonin) on phosphorolysis. Adrenaline, administered into animals anesthetized with nembutal, inhibited the glycogen phosphorolysis. Noradrenaline caused a decrease in gamma-amylolysis of glycogen in anesthetized and untreated rats. The inhibitory effect of adrenaline on glycogen gamma-amylolysis occurred in rat heart muscle only under the conditions of anesthesia.
D000768:Anesthesia, General; D000818:Animals; D001679:Biogenic Amines / Q000008:administration & dosage*; D004837:Epinephrine / Q000494:pharmacology; D004986:Ether / Q000008:administration & dosage*; D005019:Ethyl Ethers / Q000008:administration & dosage*; D005959:Glucosidases / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism*; D008297:Male; D009206:Myocardium / Q000201:enzymology / Q000378:metabolism*; D009638:Norepinephrine / Q000494:pharmacology; D010424:Pentobarbital / Q000008:administration & dosage*; D051381:Rats; D012701:Serotonin / Q000494:pharmacology; D014363:Tryptamines / Q000494:pharmacology; D014439:Tyramine / Q000494:pharmacology
D001679:Biogenic Amines; D005019:Ethyl Ethers; D014363:Tryptamines; D004986:Ether; D012701:Serotonin; D006003:Glycogen; D005959:Glucosidases; D010424:Pentobarbital; D009638:Norepinephrine; D014439:Tyramine; D004837:Epinephrine
Vliianie biogennykh aminov na fosforoliz i gamma-amiloliz glikogena v serdechnoĭ myshtse krysy pri anestezii.