[Disturbed glucose tolerance and diabetes mellitus in the relatives of patients with the juvenile form of diabetes mellitus].
A total of 200 relatives of patients with a juvenile form of diabetes mellitus were examined. The standard oral glucose tolerance test (GTT) was used with a simultaneous determination (during the test) of immunoreactive insulin (IRI) level. GTT was found to be deranged in 39% of the patients investigated (doubtful results--in 24%, latent diabetes--in 8%, manifest diabetes--in 7%). The incidence of diabetes mellitus had a direct correlation with age and weight of the patients. During the GTT IRI was found to be high in 40.8% of the cases, and torpid type of the insulinemia curve was noted in 2% of the cases only.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000941:Antigens; D002648:Child; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D008875:Middle Aged
D000941:Antigens; D007328:Insulin
Narushenie tolerantnosti k gliukoze i sakharnyĭ diabet u rodstvennikov bol'nykh s iunosheskoĭ formoĭ sakharnogo diabeta.