title: [Effects of tilidin and naloxone on pulmonary function (author's transl)].
abstract: The respiratory depressant effect of tilidine (valoron) was investigated in anaesthetized patients. One hundred mg of tilidine had a slight respiratory depressant effect which was without importance in awake subjects. The respiratory depression caused by tilidine could be antagonized by naloxone while the analgesic effect was maintained. This suggests a dissociation of the mechanisms responsible for the respiratory and the analgesic actions.
mesh_terms: D000293:Adolescent; D000328:Adult; D000698:Analgesia; D000768:Anesthesia, General; D003509:Cyclohexanecarboxylic Acids / Q000494:pharmacology*; D003864:Depression, Chemical; D004336:Drug Antagonism; D006801:Humans; D008875:Middle Aged; D009270:Naloxone / Q000494:pharmacology*; D012119:Respiration / Q000187:drug effects*; D013993:Tilidine / Q000494:pharmacology*
chemical_list: D003509:Cyclohexanecarboxylic Acids; D009270:Naloxone; D013993:Tilidine
vernacular_title: Wirkungen von Tilidin und Naloxone auf die Atemfunktion.