Comparative effects of feeding lead acetate and phospholipid-bound lead on blood and tissue lead concentrations in young and adult rats.
Two different forms of lead, lead acetate and phospholipid-bound lead, were fed to young and adult male rats for 10 weeks at the 300 ppm dietary level. Based on the lead concentrations found in selected tissues, our results indicate that the bioavailability of phospholipid-bound lead is similar to that of lead acetate at the 300 ppm level. Young rats had higher concentrations of lead in tissues than did adult rats.
D000375:Aging; D000622:Aminolevulinic Acid / Q000652:urine; D000818:Animals; D001682:Biological Availability; D001835:Body Weight / Q000187:drug effects; D004032:Diet; D007854:Lead / Q000097:blood / Q000378:metabolism*; D008297:Male; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats; D014018:Tissue Distribution
D010743:Phospholipids; D007854:Lead; D000622:Aminolevulinic Acid