[Effect of several hormones on the intensity of experimental free-radical lipid oxidation reactions].
The effect of adrenaline and hydrocortisone on the processes of free radical oxidation of lipids in rabbit erythrocytes was studied in experiment in vivo against the background of altered lipid metabolism. Adrenaline in a dose of 0.1 mg/kg and hydrocortisone in a dose of 5 mg/kg induced an increase in the amount of hydroperoxidase of fatty acids recorded by the changes of the UV spectrum. The data obtained served in confirmation of the fact that adrenaline and hydrocortisone possessed prooxidant properties, apparently mediated, this being connected with their fat mobilizing effects.
D000818:Animals; D000975:Antioxidants; D002682:Chinchilla; D003921:Diabetes Mellitus, Experimental / Q000097:blood; D004837:Epinephrine / Q000494:pharmacology*; D004912:Erythrocytes / Q000187:drug effects*; D005609:Free Radicals; D006854:Hydrocortisone / Q000494:pharmacology*; D050356:Lipid Metabolism; D010084:Oxidation-Reduction / Q000187:drug effects; D011817:Rabbits
D000975:Antioxidants; D005609:Free Radicals; D006854:Hydrocortisone; D004837:Epinephrine
Vliianie nekotorykh gormonov na intensivnost' reaktsii svobodnoradikal'nogo okisleniia lipidov v éksperimente.