title: Infections caused by Klebsiella ozaenae: a changing disease spectrum.
abstract: A total of 64 isolates of Klebsiella ozaenae were recovered from 36 patients during a 40-month period. Over 7,500 isolates of K. pneumoniae were isolated during the same time period. Before this decade, K. ozaenae was considered to be only a colonizer of the nasopharynx or a putative cause of ozena (atrophic rhinitis). K. ozaenae was recovered most frequently from sputum in mixed culture but was associated with infection in 12 patients (2 with bacteremia, 3 with urinary tract infection, 1 with soft tissue infection, and 6 with mucopurulent nasal discharge). The spectrum of disease caused by this organism is more extensive than has been appreciated previously.
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D006801:Humans; D007709:Klebsiella / Q000187:drug effects / Q000302:isolation & purification* / Q000502:physiology; D007710:Klebsiella Infections / Q000382:microbiology*; D008297:Male; D008417:Mastoiditis / Q000382:microbiology*; D008875:Middle Aged; D018805:Sepsis / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents