title: [Adipose tissue and obesity. Part 1: fat cell size and fat cell number].
abstract: The role of the number and size of adipocytes in the pathogenesis of obesity is reviewed. The observation that hyperplasia of adipose tissue is associated with child-onset obesity was over-interpreted. Nevertheless most recent studies suggest that fact cell size and number are regulated and can influence food intake. The discovery of preadipocytes has opened a new field or research offering the possibility of new concepts in the prevention and therapy of obesity.
mesh_terms: D000273:Adipose Tissue / Q000166:cytology* / Q000473:pathology; D000328:Adult; D002452:Cell Count; D002648:Child; D005247:Feeding Behavior; D006801:Humans; D006965:Hyperplasia; D006984:Hypertrophy; D007223:Infant; D007227:Infant Nutritional Physiological Phenomena; D008060:Lipodystrophy / Q000378:metabolism; D008068:Lipomatosis / Q000378:metabolism; D009765:Obesity / Q000209:etiology*
vernacular_title: Fettgewebe und Fettsucht. Teil 1: Fettzellgrösse und Fettzellzahl.