The inhibiting effect of a plasma globulin on arterial thrombus formation, (as compared to dipyridamole).
The inhibiting effect on arterial white thrombus formation of a globulin prepared from beef plasma has been compared to dipyridamole in white Wistar rats. It was demonstrated that the globulin fraction had a greater effect in inhibiting thrombus formation as judged by the lag time [t(l)], the maximal thrombus value [m(T)], the maximal thickness of the thrombus [m(D)] and the maximal thrombus surface [m(O)].
D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects; D004176:Dipyridamole / Q000494:pharmacology*; D008297:Male; D008638:Mesenteric Arteries; D051381:Rats; D012712:Serum Globulins / Q000494:pharmacology*; D013997:Time Factors
D012712:Serum Globulins; D004176:Dipyridamole