Growth of human marrow in plasma clot diffusion chambers.
Unseparated as well as nonadherent human bone marrow cells produced colonies while suspended within plasma clots contained within diffusion chambers implanted into irradiated mice. The majority of colonies consisted of granulocytes or macrophages. Colony size was significantly increased by the administration of endotoxin prior to implantation of the chambers.
D000208:Acute Disease; D001777:Blood Coagulation; D001854:Bone Marrow Cells; D002452:Cell Count; D002455:Cell Division; D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D004731:Endotoxins / Q000494:pharmacology; D006098:Granulocytes / Q000502:physiology; D006801:Humans; D007938:Leukemia / Q000503:physiopathology; D008264:Macrophages / Q000502:physiology; D008567:Membranes, Artificial
D004731:Endotoxins; D008567:Membranes, Artificial