title: Non-chromatographic screening test for hyperprolinemia.
abstract: This procedure for determining serum proline in patients with hyperprolinemia involves protein precipitation (Folin-Wu method),  color development with isatin, extraction of the color with methylene chloride and measurement of its absorbance at 600 nm. The specificity and analytical recovery show the method to be suitable for this use.
mesh_terms: D000592:Amino Acid Metabolism, Inborn Errors / Q000175:diagnosis*; D003124:Colorimetry / Q000379:methods; D006801:Humans; D008403:Mass Screening; D011392:Proline / Q000097:blood*
chemical_list: D011392:Proline