[Role of biogenic amines in the pathogenesis of intellectual disorders in children with minimal psychoorganic syndromes].
Memory, attention and emotional reactivity in comparison to indices of catecholamine and serotonin metabolism were studied in 25 children from 7 to 10 years with the minimal psychoorganic syndrome during aminalon treatment. According to the excretion indices the activity equilibrium of catecholamines and serotonin were changed and were accompanied by disturbances of memory, attention and emotional reactivity. An improvement of these indices during treatment corresponded to a normalization of the activity in these systems. Questions concerning the signficance of disturbed metabolism of biogenic amines in the pathogenesis of the psychoorganic syndrome are discussed.
D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy* / Q000523:psychology / Q000652:urine; D002395:Catecholamines / Q000652:urine*; D002648:Child; D004295:Dihydroxyphenylalanine / Q000652:urine; D004569:Electroencephalography; D004644:Emotions; D005260:Female; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000652:urine; D008297:Male; D008570:Memory, Short-Term; D013577:Syndrome; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use*
D002395:Catecholamines; D006897:Hydroxyindoleacetic Acid; D005680:gamma-Aminobutyric Acid; D004295:Dihydroxyphenylalanine
O roli biogennykh aminov v patogeneze intellektual'nykh narusheniĭ u deteĭ s minimal'nym psikhoorganicheskim sindromom.