[Research on the eventual cross-reactivity of anti-Wr(a) with various viral, bacterial and mycotic antigenes (author's transl)].
Among the sera of 1011 blood donors, they have been collected 34 anti-Wr(a) antibodies. By IgG antiglobulin test, the titer was 1/8 or more in 21 sera. After absorption on viral, bacterial and mycotic antigens, the sera were still reactive with Wr(a) + red blood cells. These results show that no tested antigen is cross-reactive with Wr(a) antigen. However, the AA. suggest that the research of a widley diffused antigen, cross-reactive with Wr(a) + red blood cells, is a valuable approach to the problem of IgG anti-Wr(a) antibodies in normal, never transfused blood donors.
D000328:Adult; D000937:Antigen-Antibody Reactions; D000942:Antigens, Bacterial; D000946:Antigens, Fungal; D000956:Antigens, Viral; D001782:Blood Donors; D001789:Blood Group Antigens; D003429:Cross Reactions; D004912:Erythrocytes; D005260:Female; D006801:Humans; D007518:Isoantibodies; D008297:Male; D008875:Middle Aged
D000942:Antigens, Bacterial; D000946:Antigens, Fungal; D000956:Antigens, Viral; D001789:Blood Group Antigens; D007518:Isoantibodies
Ricerca sulla eventuale cross-reattività dell'anti-Wr(a) con alcuni antigeni virali, batterici e micotici.