Determination of water in aluminum chlorohydrate and effervescent tablets by Karl Fischer Analysis.
A procedure was developed for the quantitative determination of loosely bound water in aluminum chlorohydrate and the water content in denture cleanser effervescent tablets. The basic method involves extracting the water from the sample into dioxane followed by titration of the dioxane in methanol with Karl Fischer Reagent. Matrix Ingredients did not interfere.
D000536:Aluminum Hydroxide / Q000032:analysis*; D003820:Denture Cleansers / Q000032:analysis; D004146:Dioxanes; D008722:Methods; D013607:Tablets / Q000032:analysis*; D014867:Water / Q000032:analysis*
D003820:Denture Cleansers; D004146:Dioxanes; D013607:Tablets; D014867:Water; D000536:Aluminum Hydroxide