The influence of hyperosmolality on heart function.
Hyperosmolality produces a reduction in myocardial water content, an increase in ventricular stiffness and coronary blood flow, and decrease in ventricular performance. The alterations of myocardial dehydration and ventricular stiffness are more pronounced in glucose-induced, and those of ventricular performance in urea-induced hyperosmolality.
D000818:Animals; D001769:Blood / Q000187:drug effects; D001786:Blood Glucose / Q000032:analysis; D001790:Blood Physiological Phenomena; D002302:Cardiac Output; D003326:Coronary Circulation; D004285:Dogs; D005260:Female; D005947:Glucose / Q000494:pharmacology; D006439:Hemodynamics; D008297:Male; D009200:Myocardial Contraction; D009994:Osmolar Concentration; D014508:Urea / Q000097:blood / Q000494:pharmacology
D001786:Blood Glucose; D014508:Urea; D005947:Glucose