Lymphocyte recirculation through the non-lymphoid tissues of normal rats.
Recirculation of lymphocytes labeled with 51Cr and 125IUDR was studied in the non-lymphoid tissues of normal rat. About 10% of the 51Cr and 40% of the 125IUDR-labeled cells were found in the extralymphoid tissues. The 125IUDR-labeled cells showed predilection toward the gut, lungs and skin. Migration of these cells to skin is an original observation, but the mechanism of the phenomenon is unknown so far.
D000818:Animals; D002465:Cell Movement; D007668:Kidney / Q000166:cytology; D008168:Lung / Q000166:cytology; D008198:Lymph Nodes / Q000166:cytology; D008208:Lymphatic System / Q000502:physiology; D008214:Lymphocytes / Q000502:physiology*; D008297:Male; D051381:Rats; D012867:Skin / Q000166:cytology; D014018:Tissue Distribution