An in vivo assessment of in vitro sensitized human lymphocytes using athymic, "nude" mice.
Cytotoxic lymphocytes were generated in vitro by co-cultivation of human peripheral blood lymphocytes with cultured human tumor cells. Their cytotoxic action was demonstrated in vivo in immunologically deficient "nude" mice.
D000818:Animals; D002471:Cell Transformation, Neoplastic; D003602:Cytotoxicity, Immunologic; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D051379:Mice; D008819:Mice, Nude; D008937:Mitomycins / Q000494:pharmacology; D009374:Neoplasms, Experimental / Q000276:immunology*; D051381:Rats; D013045:Species Specificity
D008937:Mitomycins