title: Close relation between hypothalamic and cardiac norepinephrine during stress and its role in acute myocardial infarction disrhythmias.
abstract: The decrease of the norepinephrine levels in hypothalamus and heart caused by stress is prevented by pargyline and imipramine. Such a decrease in spleen and adrenals is not affected. Chlorpromazine and lithium only prevented the norepinephrine decrease in the spleen. The uptake of H3norepinephrine by isolated atria of guinea-pig increases during anoxia; the change to a normal oxygen situation decreases these norepinephrine levels by more than 50%.
mesh_terms: D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000209:etiology*; D007031:Hypothalamus / Q000378:metabolism*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism* / Q000502:physiology; D011619:Psychotropic Drugs / Q000494:pharmacology; D051381:Rats; D012149:Restraint, Physical; D013154:Spleen / Q000378:metabolism; D013312:Stress, Physiological / Q000378:metabolism*
chemical_list: D011619:Psychotropic Drugs; D009638:Norepinephrine