Reduced immunoglobulin concentration and impaired macrophage function in mice due to diphenylhydantoin.
Diphenylhydantoin (DPH) depresses serum IgA and IgM concentrations and polyvinyl pyrrolidone (PVP) clearance in mice.
D000818:Animals; D007070:Immunoglobulin A / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D008264:Macrophages / Q000187:drug effects / Q000276:immunology*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D010672:Phenytoin / Q000494:pharmacology*; D011205:Povidone / Q000097:blood
D007070:Immunoglobulin A; D007075:Immunoglobulin M; D010672:Phenytoin; D011205:Povidone