title: Lymecycline or doxycycline for treatment of urinary-tract infections: a comparison of attained urine concentrations.
abstract: The urine and serum concentrations of lymecycline and doxycycline were investigated in a cross-over study in ten volunteers. Both drugs were found in therapeutic serum levels but lymecycline had a mean urine concentration of 240 microgram per ml compared to 60 microgram per ml of doxycycline. The results are discussed with regard to treatment of some urinary-tract infections.
mesh_terms: D004318:Doxycycline / Q000097:blood / Q000627:therapeutic use / Q000652:urine*; D004341:Drug Evaluation; D006801:Humans; D008194:Lymecycline / Q000097:blood / Q000627:therapeutic use / Q000652:urine*; D013754:Tetracyclines / Q000652:urine*; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D013754:Tetracyclines; D008194:Lymecycline; D004318:Doxycycline