Genetic and nongenetic variation in the AB0 agglutinin levels of plasma, saliva and milk.
The agglutinin levels of 250 parturient women and their newborn babies were studied and the modifying influence of 16 variables evaluated. The most important factor in this variability is the AB0 phenotype. The agglutinin titers are generally higher in milk than in plasma or saliva. Blacks always show salivary agglutinins in higher frequencies than Whites. Within each fluid the amount of anti-A and anti-B are always highly correlated (r 0.59-0.79). Associations were also observed between the titers in plasma and milk (r 0.25--0.30). The plasma and milk anti-A levels of the 0 mothers are correlated with those of their 0 children (r 0.28-0.37), but the anti-B are not. Socioeconomic conditions may affect the salivary anti-A and anti-B titers.
D000017:ABO Blood-Group System; D000293:Adolescent; D000328:Adult; D000373:Agglutinins / Q000032:analysis / Q000235:genetics*; D000375:Aging; D044383:Black People; D005260:Female; D005312:Fetal Blood; D014644:Genetic Variation; D006801:Humans; D007231:Infant, Newborn; D008895:Milk, Human / Q000276:immunology*; D010641:Phenotype; D011247:Pregnancy; D012463:Saliva / Q000276:immunology*; D012959:Socioeconomic Factors; D044465:White People
D000017:ABO Blood-Group System; D000373:Agglutinins