title: [Meningitis caused by Candida in a premature infant].
abstract: A case of Candida meningitis in a premature infant treated with amphotericin B IV for 41 days, resulted in negative CSF cultures after 5 days of therapy. Amphotericin B was also given intraventricularly for 21 days; purulent meningitis was a complication from this kind of therapy. Psychometric evaluation showed a mental age of 3 months in a chronological age of 7 months. Only one premature infant has been reported in the literature with intraventricular amphotericin B treatment. A review of Candida meningitis diagnosed before death in infants less than 1 year of age and a discussion of the modern therapy is presented.
mesh_terms: D000666:Amphotericin B / Q000008:administration & dosage* / Q000627:therapeutic use; D002177:Candidiasis / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy*; D007275:Injections, Intravenous; D007276:Injections, Intraventricular; D008581:Meningitis / Q000188:drug therapy*
chemical_list: D000666:Amphotericin B
vernacular_title: Meningitis por Candida en un prematuro.