Disseminated atypical mycobacteriosis in a child--a case of Mycobacterium sculoflaseum.
A case of disseminated mycobacterial disease caused by mycobacterium sculoflaceum is presented in a three-year-old female. Atypical acid-fast organisms were found in cultures from the tissue of lymph node and bone marrow, gastric juice and feces. Histologically the mesenteric lymph nodes contained numerous large macrophages which had large numbers of acid-fast bacilli. Caseation necrosis was absent. Distinguishing features are the extensive involvement of lymph nodes and bones and the preference for intracellular presence of acid-fast bacilli. Up to the present in Japan there are only 17 reported cases of atypical mycobacteriosis in children.
D002675:Child, Preschool; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D009164:Mycobacterium Infections / Q000473:pathology*; D009165:Mycobacterium Infections, Nontuberculous / Q000382:microbiology / Q000473:pathology*; D009170:Nontuberculous Mycobacteria / Q000302:isolation & purification