Abnormal dentition and decrease in body weight in the genetically obese mouse (genotype, ob/ob).
Loss of body weight accompanied by cannibalism occurred in obese mice (genotype, ob/ob) at seven months of age. The onset was sudden. The animals had accompanying abnormalities of their incisor teeth. Some upper incisor teeth had no erupted part. The unerupted part of all the incisor teeth showed ridged thickening. Body weight loss was prevented by grinding the pelleted food to a powder. Possible causes of the teeth abnormalities are discussed.
D000821:Animal Feed; D000818:Animals; D001835:Body Weight; D005838:Genotype; D007180:Incisor / Q000002:abnormalities / Q000000981:diagnostic imaging; D051379:Mice; D008820:Mice, Obese; D011859:Radiography; D014071:Tooth Abnormalities / Q000235:genetics*; D014097:Tooth, Unerupted