title: On the metabolic detoxication of 4-iodothymol in man.
abstract: The detoxication of 4-iodothymol was investigated in man. A new metabolite was isolated as a crystalline derivative from 4-iodothymol medicated urine and identified as 4-iodothymol glucuronide as a methyl acetyl derivative. The deiodinated metabolite of 4-iodothymol, thymoquinone, was also recognized in a very small amount in 4-iodothymol medicated urine.
mesh_terms: D000871:Anthelmintics / Q000378:metabolism* / Q000652:urine; D002849:Chromatography, Gas; D005965:Glucuronates / Q000652:urine; D006801:Humans; D006868:Hydrolysis; D008658:Inactivation, Metabolic; D013943:Thymol / Q000031:analogs & derivatives* / Q000378:metabolism / Q000652:urine
chemical_list: D000871:Anthelmintics; D005965:Glucuronates; C008156:4-iodothymol; D013943:Thymol