[Myocardial potassium and H-ion loss during normothermic, ischemic heart arrest].
Arterial and venous [K+] and [H+] concentrations were determined during normothermic ischemic arrest in cat hearts intermittently perfused without resuscitation. The slight loss in [K+] was taken as evidence of a stable membrane potential. The decrease in [H+] activity appearing in the perfusate correlated well with the previously described increase in coronary resistance. This was interpreted as a sign of restricted coronary perfusion and not as evidence for reduced anaerobic metabolic activity. Thus the functional impairment of the coronary system was confirmed to be a limiting factor when resuscitating ischemically arrested hearts.
D000818:Animals; D001831:Body Temperature; D002415:Cats; D002462:Cell Membrane / Q000378:metabolism; D006324:Heart Arrest, Induced; D006859:Hydrogen / Q000378:metabolism*; D007477:Ions; D007511:Ischemia / Q000378:metabolism; D008564:Membrane Potentials; D009206:Myocardium / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism*
D007477:Ions; D006859:Hydrogen; D011188:Potassium
Myokardiale Kalium- und H-Ionen-Verluste während normothermer, ischämischer Herzstillstände.