title: Middle molecules re-examined.
abstract: Evidence for and against the presence and pathophysiologic importance of middle molecules in uremia is reviewed. The evidence favors both their presence and importance.
mesh_terms: D005374:Filtration; D006464:Hemoperfusion; D006801:Humans; D010530:Peritoneal Dialysis; D006435:Renal Dialysis; D014118:Toxins, Biological / Q000378:metabolism; D014511:Uremia / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy
chemical_list: D014118:Toxins, Biological