title: [OH]- negative chemical ionization mass spectrometry. Reactions of [OH]- with methadone, l-alpha-acetylmethadol and their metabolites.
abstract: The [OH]- chemical ionization spectra of methadone and three metabolites and of l-alpha-methadol and six metabolites are presented. The spectra are simple, but the methadol compounds exhibit much fragmentation. The ionization sensitivity is somewhat greater than that in CH4 positive chemical ionization.
mesh_terms: D000838:Anions; D005609:Free Radicals; D006801:Humans; D006878:Hydroxides; D013058:Mass Spectrometry / Q000379:methods*; D008691:Methadone / Q000031:analogs & derivatives / Q000378:metabolism; D008692:Methadyl Acetate / Q000378:metabolism
chemical_list: D000838:Anions; D005609:Free Radicals; D006878:Hydroxides; D008692:Methadyl Acetate; D008691:Methadone