Preparation and purification of estriol, estradiol, and progesterone labeled with radioactive iodine.
Steroids labeled with radioactive isotopes are useful tracers for radio-immunoassay and for in vivo nuclear medecine purposes. We here report and discuss methods for direct labeling of the steroids estriol, estradiol, and progesterone with radioiodine-125 or -131. The purification procedure and some chemical and physical properties of the purified labeled materials are referred to and discussed.
D002700:Chloramines; D002855:Chromatography, Thin Layer; D004355:Drug Stability; D004586:Electrophoresis; D004958:Estradiol / Q000302:isolation & purification*; D004964:Estriol / Q000302:isolation & purification*; D007455:Iodine / Q000031:analogs & derivatives; D007457:Iodine Radioisotopes; D007553:Isotope Labeling / Q000379:methods*; D007784:Lactoperoxidase; D011374:Progesterone / Q000302:isolation & purification*
D002700:Chloramines; D007457:Iodine Radioisotopes; D011374:Progesterone; D004958:Estradiol; D007455:Iodine; D007784:Lactoperoxidase; D004964:Estriol