title: Scanning-electron microscopy of chromosome aberrations.
abstract: This study is the first report of scanning-electron microscopy of isolated and purified metaphase chromosomes containing drug-induced aberrations. The technique reported allows high resolution topological examination of chromosomal aberrations which may pass undetected with conventional techniques.
mesh_terms: D002460:Cell Line; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects / Q000648:ultrastructure*; D004317:Doxorubicin / Q000494:pharmacology; D008855:Microscopy, Electron, Scanning / Q000379:methods*; D009153:Mutagens
chemical_list: D009153:Mutagens; D004317:Doxorubicin