[Serum antiprotease activity following parenteral administration of proteolytic enzymes, histamine and acetylcholine].
State of tryptic and antienzymatic activities of rabbit blood serum was studied after parenteral administration of trypsin, chymotrypsin, histamine, acetylcholine and kallikrein. Treatment with chymotrypsine led to the most favorable alterations in animals as compared with trypsin and kallikrein effects. Activity of trypsin was increased and the antienzymatic activity was decreased in blood serum after administration of histamine and acetylcholine. This suggests that antiprotease drugs may be used in therapy of diseases, accompanied by increase in content of histamine and acetylcholine.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D002918:Chymotrypsin / Q000037:antagonists & inhibitors / Q000494:pharmacology; D006632:Histamine / Q000494:pharmacology*; D007610:Kallikreins / Q000037:antagonists & inhibitors / Q000494:pharmacology; D010447:Peptide Hydrolases / Q000494:pharmacology*; D011480:Protease Inhibitors / Q000097:blood*; D011817:Rabbits; D014357:Trypsin / Q000494:pharmacology; D014361:Trypsin Inhibitors / Q000097:blood
D011480:Protease Inhibitors; D014361:Trypsin Inhibitors; D006632:Histamine; D010447:Peptide Hydrolases; D007610:Kallikreins; D002918:Chymotrypsin; D014357:Trypsin; D000109:Acetylcholine
Antiproteaznaia aktivnost' syvorotki krovi pri parenteral'nom vvedenii proteoliticheskikh fermentov, gistamina i atsetilkholina.