title: Results of prolonged bladder distension as treatment for detrusor instability.
abstract: Forty-six patients with urinary symptoms associated with unstable (uninhibitable) detrusor contractions have been treated by a total of 58 bladder distensions; 43 of these were fully re-evaluated urodynamically thereafter and none showed conversion from unstable to stable detrusor behaviour. Four patients with unstable bladders were symptomatically improved but 5 patients reported symptomatic deterioration. We have concluded that while over-distension may sometimes improve a patient's symptoms, it did not result in the abolition of detrusor contractions or the reversal of unstable detrusor behaviour.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004106:Dilatation / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D009119:Muscle Contraction; D011312:Pressure; D012421:Rupture; D001743:Urinary Bladder / Q000293:injuries / Q000503:physiopathology; D001745:Urinary Bladder Diseases / Q000503:physiopathology / Q000628:therapy*; D014555:Urination Disorders / Q000503:physiopathology / Q000628:therapy*