[Effect of anti-inflammatory drugs on the motility of human polymorphonuclear granulocytes].
Polymorphonuclear leucocytes play an important role in the inflammatory process, and their functions are likely to be regulated by pharmacological agents. In this paper we report the "in vitro" effect of non steroidal anti-inflammatory drugs on random and chemotactic motility of human leucocytes, and demonstrate that the two forms of movement, spontaneous and directional, are differently inhibited by low concentrations of these agents. Leucocytes of patients with recurrent inflammation are unaffected by these drugs.
D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002364:Caseins / Q000494:pharmacology; D002634:Chemotaxis, Leukocyte / Q000187:drug effects*; D006098:Granulocytes / Q000187:drug effects*; D006801:Humans; D066298:In Vitro Techniques; D009504:Neutrophils / Q000187:drug effects*
D000893:Anti-Inflammatory Agents; D002364:Caseins
Effetto di farmaci anti-infiammatori sulla motilità dei granulociti polimorfonucleati umani.