title: A study of cell surface constituents restricting Salmonella minnesota R form glycopid mR595 fixation to normal rat embryo fibroblasts.
abstract: The nature of the cell surface constituent(s) containing sialic acid that block fixation of bacterial glycolipid mR595 to normal rat fibroblasts was explored. Indirect evidence suggests that a trypsin-sensitive, high molecular weight glycoprotein, present in larger amounts on the surface of normal cells (as compared with transformed rat fibroblasts), may be involved as a blocking agent.
mesh_terms: D000818:Animals; D001692:Biological Transport; D002241:Carbohydrates / Q000032:analysis; D002462:Cell Membrane / Q000378:metabolism*; D002478:Cells, Cultured; D004622:Embryo, Mammalian; D005260:Female; D005347:Fibroblasts / Q000378:metabolism; D006017:Glycolipids / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism; D051379:Mice; D011485:Protein Binding; D051381:Rats; D012475:Salmonella; D012794:Sialic Acids / Q000032:analysis; D012795:Sialoglycoproteins / Q000378:metabolism*
chemical_list: D002241:Carbohydrates; D006017:Glycolipids; D008565:Membrane Proteins; D012794:Sialic Acids; D012795:Sialoglycoproteins