[Therapeutic trials of a new anti-helminthic in Colombian Amazonia: flubendazole].
After a coprologic survey made at Araracuara, a village in colombian Amazonia showing high prevalences of nematodosis, 83 villages (including 55 children below twelve) were given Flubendazole during three consecutive days. The total dose was 600 mg. for children below 12, and 900 mg. for adults. The product efficiency was 88% for Trichuris, 82% for Hookworm, 77% for Ascaris and 43% for Strongyloïdes. The tolerance was excellent in all cases, in spite of heavy parasital infection. The Flubendazole's effect seems to be particularly interesting by its polyvalency.
D000724:Ancylostomiasis / Q000188:drug therapy; D000871:Anthelmintics / Q000627:therapeutic use*; D000969:Antinematodal Agents / Q000627:therapeutic use*; D001196:Ascariasis / Q000188:drug therapy; D001200:Ascaris; D001562:Benzimidazoles / Q000627:therapeutic use*; D008463:Mebendazole / Q000031:analogs & derivatives / Q000627:therapeutic use*; D009349:Nematode Infections / Q000188:drug therapy*; D013322:Strongyloidiasis / Q000188:drug therapy; D014259:Trichuroidea
D000871:Anthelmintics; D000969:Antinematodal Agents; D001562:Benzimidazoles; D008463:Mebendazole
Essai thérapeutique d'un nouvel anti-helminthique en amazonie colombienne: le flubendazole.