Syntheses of N-alkyl-N-(omega-carboxyalkyl)nitrosamines related to N-butyl-N-(3-carboxypropyl)nitrosamine, principal urinary metabolite of a potent bladder carcinogen N-butyl-N-(4-hydroxybutyl)nitrosamine.
D000478:Alkylation; D000818:Animals; D002273:Carcinogens / Q000652:urine*; D006885:Hydroxybutyrates / Q000652:urine*; D009602:Nitrosamines / Q000138:chemical synthesis*; D051381:Rats; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced*
D002273:Carcinogens; D006885:Hydroxybutyrates; D009602:Nitrosamines