title: [Optimization of therapy using cardiac glycosides].
abstract: By the estimation of the serum glycoside concentration during the last years numerous new recognitions have been got, particularly concerning the pharmacokinetics of the heart glycosides, which increasingly will be reflected in the clinical practice. Apart from thoughts on pharmacokinetics the author adopts a definite attitude to glycoside tolerance, to the influence of age and bodyweight as well as to the importance of disturbances of the renal function. Moreover it is referred to new aspects in the dosage of heart glycosides, in which case the revision of the central therapy recommendations seems to be necessary.
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001835:Body Weight; D002301:Cardiac Glycosides / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use*; D006333:Heart Failure / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007674:Kidney Diseases / Q000150:complications; D007700:Kinetics; D008875:Middle Aged
chemical_list: D002301:Cardiac Glycosides
vernacular_title: Zur Optimierung der Therapie mit Herzglykosiden.