[Myocardial protective effect using membrane stabilization in ischemic heart arrest in hypothermia].
Membrane stabilization with steroid pretreatment, procaine, or both protect against postischemic left ventricular performance after one hour of topical hypothermic ischemic arrest, but do not prevent myocardial edema. Combining steroids and procaine provide no apparent added benefit, but procaine has the technical advantage of almost immediate cardioplegia.
D000818:Animals; D002462:Cell Membrane / Q000187:drug effects; D004285:Dogs; D006321:Heart / Q000187:drug effects*; D006324:Heart Arrest, Induced; D007036:Hypothermia, Induced; D007511:Ischemia / Q000517:prevention & control; D008775:Methylprednisolone / Q000494:pharmacology*; D011343:Procaine / Q000494:pharmacology*; D013997:Time Factors
D011343:Procaine; D008775:Methylprednisolone
Myokardprotektiver Effekt durch Membranstabilisierung bei ischämischem Herzstillstand in Hypothermie.