title: Effect of Pb++ on Fe+++ tissue concentrations and delta-aminolaevulinic acid dehydratase activity in Lumbricus terrestris.
abstract: Iron was found at the highest concentration in the chloragogenous tissue with smaller amounts in the intestine and the lowest concentration in the body wall. Earthworms treated with Pb++ for 20 days showed a decrease in the concentration of Fe+++ in the intestinal tissue but no significant changes in the other tissue. The enzyme delta-aminolaevulinic acid dehydratase (ALAD) was not detected in isolated chloragosomes but it was found in the chloragocyte cytosol, body wall and intestine. L. terrestris treated with Pb++ showed a decrease in the activity of ALAD in all tissues where it was located and particularly in the chloragocyte cytosol.
mesh_terms: D000818:Animals; D005290:Ferric Compounds / Q000378:metabolism*; D007501:Iron / Q000378:metabolism*; D007854:Lead / Q000494:pharmacology*; D009835:Oligochaeta / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D000623:Porphobilinogen Synthase / Q000378:metabolism*; D014018:Tissue Distribution
chemical_list: D005290:Ferric Compounds; D007854:Lead; D007501:Iron; D000623:Porphobilinogen Synthase