title: Influence of serotonin on calcium transport in rat liver mitochondria.
abstract: It was shown in experiments in vitro that serotonin, depending on the concentration, has different effects on calcium transport in rat liver mitochondria. In a concentration of 10(-6) M it increases the ability of the mitochondria to bind calcium; in a higher concentration (10(-4) M) serotonin accelerates the release of calcium from the mitochondria. The effect of serotonin is detected at a calcium concentration in sucrose medium of the order of 10(-4) M and is not observed when the mitochondria are incubated in a complete reaction medium.
mesh_terms: D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002118:Calcium / Q000378:metabolism*; D002474:Cell-Free System; D008930:Mitochondria, Liver / Q000378:metabolism*; D010539:Permeability; D051381:Rats; D012701:Serotonin / Q000494:pharmacology*
chemical_list: D012701:Serotonin; D002118:Calcium