Locomotion and phagocytosis of polymorphonuclear leukocytes (PMNs) in infected urine. Reversal of PMN polarity.
The appearance of polymorphonuclear leukocytes (PMNs), fixed during locomotion and phagocytosis in deposits of infected urine, is described. By comparison with previous observations on vital PMNs, it is inferred that the anterior lamellipodium is the direction-choosing and prey-catching cell organelle. During phagocytosis the lamellipodium may assume such proportions that a reversal of cell polarity is produced, i.e., the lamellipodium forms the handle of a hand-mirror cell.
D002465:Cell Movement; D006801:Humans; D066298:In Vitro Techniques; D010587:Phagocytosis; D014556:Urine / Q000166:cytology / Q000382:microbiology*