Posterior choroidal involvement in Letterer-Siwe disease.
A five-year-old child with Letterer-Siwe disease in remission was found to have decreased vision in on eye produced by a choroidal mass and secondary retinal detachment with cystic degeneration. Echography confirmed a vascularized disciform-like mass with possible involvement of the optic nerve. Florescein angiography showed a well vascularized, intensely staining lesion, with optic disc edema, destruction of the retinal pigment epithelium and cystoid macular edema.
D000293:Adolescent; D002675:Child, Preschool; D002830:Choroid Neoplasms / Q000150:complications* / Q000175:diagnosis; D003560:Cysts / Q000150:complications; D004487:Edema / Q000150:complications; D005260:Female; D005451:Fluorescein Angiography; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007223:Infant; D008266:Macula Lutea; D008297:Male; D010211:Papilledema / Q000150:complications; D012163:Retinal Detachment / Q000150:complications; D012164:Retinal Diseases / Q000150:complications*