title: Continuous monitoring of temperature in laboratory animals during inhalation exposure.
abstract: An automatic system was developed to monitor continuously the colonic temperature of laboratory animals during inhalation exposure to toxic chemicals. It includes: an automatic switchbox, a control circuit, a recorder and a digital voltmeter. The system was calibrated for different temperature ranges and used for a year to assess the effects of household solvents on temperature of Sprague-Dawley rats. Reliable monitoring of temperature in 16 rats was carried out in a sequential manner in the manual mode or in the automatic mode for several consecutive days. Very slight changes (.01 - .02 degrees C) in temperature can be measured with this system.
mesh_terms: D000818:Animals; D001831:Body Temperature; D004581:Electronics; D005260:Female; D005740:Gases; D008297:Male; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000662:veterinary*; D011433:Propranolol / Q000008:administration & dosage; D051381:Rats; D013817:Thermography / Q000295:instrumentation*; D014116:Toxicology / Q000295:instrumentation*
chemical_list: D005740:Gases; D011433:Propranolol