title: Effect of tryptophan on hepatic nuclear free and engaged RNA-polymerases in young and adult rats.
abstract: Whereas in young rats (2 weeks old), administration of typtophan produced marked enhancement in the activity of both engaged and free polymerases of nuclei, in adult rats (10 weeks old) only the engaged polymerases showed higher activities following tryptophan force-feeding.
mesh_terms: D000367:Age Factors; D000546:Amanitins / Q000494:pharmacology; D002467:Cell Nucleus / Q000201:enzymology; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D012319:RNA Polymerase II / Q000037:antagonists & inhibitors; D014364:Tryptophan / Q000494:pharmacology*
chemical_list: D000546:Amanitins; D014364:Tryptophan; D012319:RNA Polymerase II; D012321:DNA-Directed RNA Polymerases