H-Y antigen in testes of XX(BALB)/XY (C3H) chimaeric male mouse.
Among experimentally produced BALB/C3H aggregation (Blastocyst fusion) chimaeras of the mouse, one fertile XX (BALB)/XY (C3H) male was identified who maintained 50% or more female cells in many parts of his body. Results of H-Y antibody absorption tests revealed an XY to XX transfer of testis-organizing H-Y antigen among testicular Sertoli and Leydig cells, but not among spleen and epidermal cells.
D000818:Animals; D002678:Chimera; D006649:Histocompatibility Antigens / Q000032:analysis*; D007125:Immunogenetics; D007985:Leydig Cells / Q000276:immunology / Q000648:ultrastructure; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D012708:Sertoli Cells / Q000276:immunology / Q000648:ultrastructure; D012730:Sex Chromosomes; D012867:Skin / Q000276:immunology / Q000648:ultrastructure; D013154:Spleen / Q000276:immunology / Q000648:ultrastructure; D013737:Testis / Q000276:immunology* / Q000648:ultrastructure; D014998:Y Chromosome / Q000276:immunology
D006649:Histocompatibility Antigens