The in vivo phagocytosis and intracellular killing of staphylococcal mutants by guinea pig peritoneal exudate cells.
The rate of phagocytosis and intracellular killing of staphylococcal mutants of different cell wall structure or those deprived of alpha-toxin production was studied in vivo in guinea pig peritoneal cavity. All mutants were ingested and killed at minor rates than standard S. aureus strains but only in the first hour of the observations.
D000818:Animals; D001202:Ascitic Fluid / Q000276:immunology*; D002473:Cell Wall / Q000276:immunology; D005122:Exudates and Transudates / Q000276:immunology; D006168:Guinea Pigs; D009154:Mutation; D010587:Phagocytosis; D013211:Staphylococcus aureus / Q000235:genetics / Q000276:immunology*