[The outlook and the quality of pregnancies resulting from treatment with clomiphene citrate and chorionic gonadotrophin. 53 consecutive cases (author's transl)].
The study of 53 pregnancies which were the result of induction of ovulation using a standard treatment with 100 mg of clomiphene citrate and 3 injections of 1,500 I.U. of H.C.G. showed no increase in the risk of fetal malformation. Before treatment this same group of women has a high risk of spontaneous abortion (43p. 100). After treatment in 53 conceptions 7 ended with an abortion which, is 13p. 100. The risks which follow this treatment are above all dominated by the definite increase in twin pregnancies and in prematurity which follows from this factor.
D000014:Abnormalities, Drug-Induced; D000022:Abortion, Spontaneous / Q000209:etiology; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D002996:Clomiphene / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D010062:Ovulation Induction; D011247:Pregnancy; D011272:Pregnancy, Multiple; D012306:Risk
D006063:Chorionic Gonadotropin; D002996:Clomiphene
Avenir et qualité des grossesses obtenues par l'association citrate de clomifène et gonadotrophine chorionique. A propos de 53 cas en série continue.