title: Percutaneous anaesthesia for dermabrasion.
abstract: An epicutaneously applied solution--A 2358, (Ane-Pad)--containing ketocaine has been used to bring about anaesthesia for dermabrasion in 20 cases. The time of application was 60 min and the amount of ketocaine applied varied from 0.8 to 2.5 g. In order to ensure good contact between the compresses containing the anaesthetic solution and uneven or concave skin surfaces, pressure was applied with the aid of foam plastic. Erythema and oedema were noted as unintended effects. They did not present an inconvenience during the operations or postoperatively. The operation proved to be completely painless for 15 of the patients. None of the remaining 5 patients required complementary anaesthesia, but in one case a slight sensation of pain was evident locally and in 4 cases the patients experienced an intense sensation of warmth.
mesh_terms: D000433:1-Propanol; D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D000772:Anesthesia, Local / Q000379:methods*; D000779:Anesthetics, Local; D002090:Butyrophenones / Q000008:administration & dosage; D003869:Dermabrasion; D004338:Drug Combinations; D005145:Face; D005260:Female; D005990:Glycerol; D006801:Humans; D008297:Male; D008397:Masks; D008875:Middle Aged; D010969:Plastics; D013997:Time Factors
chemical_list: D000779:Anesthetics, Local; D002090:Butyrophenones; D004338:Drug Combinations; D010969:Plastics; D000433:1-Propanol; D005990:Glycerol