Effects of d1-methadone and morphine on developing chick embryo.
Injections of methadone into the air space of fertile chicken eggs affected development of the embryo. Both methadone and morphine caused decreases in liver weight and brain protein, and morphine increased liver protein levels.
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000196:embryology / Q000378:metabolism; D002642:Chick Embryo / Q000187:drug effects* / Q000254:growth & development; D008099:Liver / Q000187:drug effects / Q000196:embryology / Q000378:metabolism; D008691:Methadone / Q000494:pharmacology*; D009020:Morphine / Q000494:pharmacology*; D011506:Proteins / Q000378:metabolism
D011506:Proteins; D009020:Morphine; D008691:Methadone