Familial pericentric inversion of chromosome 1 with a note on reproductive risks.
An inversion of chromosome 1 was found in three normal members of a two generation family. G- and C-banding studies revealed inv(1)(p13q23). The problems encountered in counseling such normal carriers are discussed.
D000328:Adult; D002871:Chromosome Banding; D007446:Chromosome Inversion; D002900:Chromosomes, Human, 1-3; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D010375:Pedigree; D010641:Phenotype; D012306:Risk