Cytogenetic polymorphism or Y/15 translocation in a black male with ambiguous genitalia.
A black male with ambiguous genitalia was found to have presumptive Y/15 translocation (46,XY,der(15) ? t(15;Y) (13;q12.2). The proband inherited this translocation from his father. All banding techniques were utilized to determine whether this was a polymorphism or a Y/15 translocation. No definite conclusion was reached but the results of QFQ, RFA, CBG, and GTG banding techniques are highly suggestive of Y/15 translocation.
D002648:Child; D002901:Chromosomes, Human, 13-15; D003937:Diagnosis, Differential; D014644:Genetic Variation; D005837:Genitalia, Male / Q000002:abnormalities; D006801:Humans; D008297:Male; D010641:Phenotype; D012730:Sex Chromosomes; D014178:Translocation, Genetic; D014998:Y Chromosome