title: Systolic arterial hypertension and cerebral ischemia.
abstract: Systolic arterial hypertension in subjects with regional cerebral ischemia is considered and discussed as regards its frequency and its pathogenetic meaning, and criteria concerning the way of treating it. Systolic arterial hypertension presents a very high frequency in these subjects. At times it is accompanied by moderate diastolic hypertension, to which may be attributed, by way of hypothesis, a compensatory meaning. Considering the pathogenesis of systolic hypertension, the antihypertensive drugs at our disposal do not offer any valid and rational indication. We advance the opinion that a lowering of blood pressure in these subjects may be more harmful than helpful.
mesh_terms: D002545:Brain Ischemia / Q000150:complications* / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology