[Specific ENT involvement in a case of angio-immunoblastic adenopathy (author's transl)].
The authors report the case of a 78 year old man with an unusual localization (soft palate and tonsil) of an angio-immunoblastic lymphadenopathy. Clinically, the syndrome combines fever, a marked change in general condition, multiple lymphadenopathy and skin rash. From a laboratory standpoint, the picture is dominated by polyclonal hypergammaglobulinemia, often associated with a hemolytic anemia. Histologically, only lymphnode biopsy allows the diagnosis to be made, with the following findings: disruption of the normal architecture of the node, marked vascular neogenesis, presence of acidophilic interstitial substance, lympho-plasmo-immunoblastic proliferation. The course is in general rapidly fatal despite corticosteroids and multiple chemotherapy.
D000368:Aged; D003937:Diagnosis, Differential; D006644:Histiocytes / Q000473:pathology; D006689:Hodgkin Disease / Q000473:pathology; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000473:pathology*; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D010160:Palate, Soft / Q000473:pathology*; D014066:Palatine Tonsil / Q000473:pathology*
Atteinte O.R.L. spécifique au cours d'une adénopathie angio-immunoblastique.