[Morphometric analysis of lymphoid organs in the hypophysectomized rat].
The effects of hypophysectomy on the lymphoid organs were evaluated in Wistar rats by morphometrical analysis: after 30 days the percentage of thymus cortical area and lymph node paracortical areas were reduced. In the thymus cortex, signs of orthological involution (e.c.: nodular cortex) appeared. A significant enlargement of lymph node cortical areas, containing a high number of germinal centers with degenerative changes, could be seen. These findings suggest a significant trophic action of hypophysis on thymus and, perhaps, an impaired lymph node antibody mediated response due to the loss of T-B cooperation.
D000818:Animals; D005260:Female; D007016:Hypophysectomy; D007111:Immunity, Cellular; D008198:Lymph Nodes / Q000033:anatomy & histology; D008221:Lymphoid Tissue / Q000033:anatomy & histology*; D009929:Organ Size; D010902:Pituitary Gland / Q000502:physiology; D051381:Rats; D013154:Spleen / Q000033:anatomy & histology; D013950:Thymus Gland / Q000033:anatomy & histology
Analisi morfometrica degli organi linfoidi nel ratto ipofisecto mizzato.