[Increased kidney cell proliferation caused by folic acid treatment after dichromate induced renal failure (author's transl)].
Folic acid is given intravenously to rats 5 to 10 days after a dichromate induced damage of the kidneys. These injection cause an additional damage in the function and structure of the kidneys, but on the other hand, they induce a cell proliferation detected by the increased uptake of thymidine. This cell proliferation in the kidney-tissue seems to be a part of specific reactions to the folic acid.
D000818:Animals; D001345:Autoradiography; D002455:Cell Division / Q000187:drug effects*; D005492:Folic Acid / Q000494:pharmacology*; D007668:Kidney / Q000187:drug effects; D007674:Kidney Diseases / Q000139:chemically induced / Q000473:pathology*; D008297:Male; D011192:Potassium Dichromate; D051381:Rats
D005492:Folic Acid; D011192:Potassium Dichromate
Proliferationssteigerung im Nierengewebe durch Folsäure nach induziertem Nierenversagen mit Dichromat.