title: Secondary metabolism: regulation by phosphate and trace elements.
abstract: Secondary metabolism and cellular differentiation occur within a range of concentrations of phosphate and, in specific taxonomic groups, of zinc, manganese, and/or iron that is much narrower than that permittee for primary metabolism. Possible molecular sites of action of the four elements are reviewed.
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D001407:Bacillus / Q000378:metabolism; D001419:Bacteria / Q000187:drug effects / Q000378:metabolism*; D007501:Iron / Q000494:pharmacology; D008345:Manganese / Q000494:pharmacology; D010710:Phosphates / Q000494:pharmacology*; D011549:Pseudomonas / Q000378:metabolism; D014131:Trace Elements / Q000494:pharmacology*; D015032:Zinc / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D010710:Phosphates; D014131:Trace Elements; D008345:Manganese; D007501:Iron; D015032:Zinc