The retention of circulating Walker-256 cells by Walker-256 tumours.
When Walker-256 cancer cells are injected into the portal veins of rats bearing Walker-256 tumours in their livers, the retention of the injected cancer cells by the tumours is considerably less than in the surrounding liver. After applying defined general criteria for "homing" phenomena to the data, it is concluded that compared with the liver, they demonstrate "antihoming". The observations are explained in terms of a deficient arrest process within the tumours.
D000818:Animals; D002279:Carcinoma 256, Walker / Q000503:physiopathology; D017707:Erythrocyte Transfusion; D008099:Liver / Q000503:physiopathology; D008113:Liver Neoplasms / Q000503:physiopathology; D009368:Neoplasm Transplantation; D009360:Neoplastic Cells, Circulating; D051381:Rats; D014184:Transplantation, Homologous