title: Pericentric inversions inv(2)(p11q13) and inv(2)(p13q11) in 2 unrelated families.
abstract: Pericentric inversions in chromosome 2 were traced in 2 unrelated North American black families. In the case of inv(2)(p13q11) no effect on reproduction was observed. In the case of inv(2)(p11q13) some reproductive abnormalities were noted which might be related to the inversion.
mesh_terms: D000755:Anemia, Sickle Cell / Q000235:genetics*; D007446:Chromosome Inversion; D002900:Chromosomes, Human, 1-3; D005260:Female; D005298:Fertility; D005796:Genes; D008040:Genetic Linkage; D006801:Humans; D007621:Karyotyping; D008297:Male