Tumor immunity following cryosurgery or electrocauterization.
Cryosurgery of MCA-10 in C57BL mice resulted in significantly greater humoral and lymphocyte-mediated cytotoxicity to MCA-10 target cells than in untreated, tumor-bearing mice or animals which had undergone tumor amputation. This result was tumor specific and could be reproduced by treatment of the tumor-bearing and amputated mice with frozen exogenous tumor antigen. A similar response was produced by electrocauterization of tumor.
D000818:Animals; D003452:Cryosurgery; D003602:Cytotoxicity, Immunologic; D004564:Electrocoagulation; D007109:Immunity; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D008810:Mice, Inbred C57BL; D012513:Sarcoma, Experimental / Q000276:immunology / Q000601:surgery*