[Comparative study in nuclear and cytoplasmic RNA species of mouse liver, Guelstein ascites hepatoma 22A and liver of tumor-bearing animals].
A comparative study on nuclear and cytoplasmic DNA-like RNA species from normal liver, malignant Guelstein hepatoma 22A and liver of tumor-bearing animals was carried out. The nuclear RNA's were found to be poorly and rapidly labelling, the latter comprising a lesser proportion in hepatoma as compared with a normal liver. The comparison of labelling rates of nuclear and cytoplasmic RNA species shows that the nucleus-to-cytoplasme RNA transport is accelerated in hepatoma. Besides, cytoplasmic DNA-like RNA's are more heterogeneous in hepatoma and liver of tumor-bearing animals than in normal liver cells.
D000818:Animals; D001692:Biological Transport; D002467:Cell Nucleus / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D008114:Liver Neoplasms, Experimental / Q000378:metabolism*; D051379:Mice; D012313:RNA / Q000378:metabolism*; D012334:RNA, Neoplasm / Q000378:metabolism
D012334:RNA, Neoplasm; D012313:RNA
Sravnitel'noe issledovanie iadernykh i tsitoplazmaticheskikh RNK kletok normal'noĭ pecheni myshi, gepatomy 22A gel'shteĭn i pecheni zhivotnogo-opukholenositelia.