title: 99mTc-diethyl-HIDA: a contribution to the study of its structure.
abstract: Sephadex column chromatography has shown that 99mTc-diethyl-HIDA consists of two clearly separable components. One of them seems to be an intermediate compound changing into the other, almost completely within two hours after reconstitution of the diethyl-HIDA (Solco HIDA) with pertechnetate. The two components could be the mono- and biscomplex of N-(2,6-diethyl-acetanilid)-imino diacetic acid with one atom of technetium. Animal experiments show that there is no important difference in the biological distribution in mice between the two components.
mesh_terms: D000818:Animals; D007082:Ileum / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008012:Lidocaine / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D051379:Mice; D013667:Technetium; D013678:Technology, Pharmaceutical
chemical_list: D013667:Technetium; D008012:Lidocaine