[Electroencephalographic observations after therapy with vincristine (author's transl)].
A direct cytotoxic effect of vincristine on the neurons, especially the cerebral cortex is discussed in the literature. In 188 patients treated with vincristine we saw no so called "Vincristine-induced Encephalopathy". In 67 children investigated 5 weeks up to 2 years after the last vincristine-injection we found no changes in EEG-tracings which could be discussed as vincristine-induced.
D001927:Brain Diseases / Q000139:chemically induced*; D002540:Cerebral Cortex / Q000187:drug effects; D002648:Child; D004569:Electroencephalography; D005500:Follow-Up Studies; D006801:Humans; D007938:Leukemia / Q000188:drug therapy; D009369:Neoplasms / Q000188:drug therapy; D009474:Neurons / Q000187:drug effects; D014750:Vincristine / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*
D014750:Vincristine
EEG-Befunde nach Vincristinbehandlung.