[Absence of a mutagenic effect of cadmium and zinc salts in mouse somatic and sex cells].
Mutagenic effect of cadmium chloride and zinc chloride on the yield of chromosome aberrations induced in bone marrow cells and the frequency of dominant lethal mutations induced by zinc chloride in male germ mouse cells are studied. Water solutions of CdCl2 and ZnCl2 were injected intraperitoneally to male mice at doses of 4 and 15 mg/kg respectively. The results obtained did not reveal any mutagenic effect of these salts in somatic cells and of ZnCl2 in germ cells of mice.
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects* / Q000648:ultrastructure; D002104:Cadmium / Q000494:pharmacology*; D002869:Chromosome Aberrations; D005799:Genes, Dominant / Q000187:drug effects; D005804:Genes, Lethal / Q000187:drug effects; D008297:Male; D051379:Mice; D009153:Mutagens; D009154:Mutation / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects*; D015032:Zinc / Q000494:pharmacology*
D009153:Mutagens; D002104:Cadmium; D015032:Zinc
Otsutstvie mutagennogo éffekta soleĭ kadmiia i tsinka v somaticheskikh i polovykh kletkakh myshi.