Effects of desoxycorticosterone acetate on renal structure in the mouse and in the European Eel.
The administration of desoxycorticosterone acetate (DOCA) induces morphological changes in the kidney of mice and eels. Such changes mainly concern the cells of the distal tubules and collecting tubules. These changes are consistent with the hypothesis that the hormone would exert a different action in Mammals and in Teleosts.
D000818:Animals; D003900:Desoxycorticosterone / Q000009:adverse effects / Q000494:pharmacology*; D004524:Eels; D005060:Europe; D005260:Female; D007668:Kidney / Q000187:drug effects*; D007685:Kidney Tubules, Collecting / Q000187:drug effects / Q000473:pathology; D008297:Male; D051379:Mice
D003900:Desoxycorticosterone