title: Reducing epileptic seizures through operant conditioning of central nervous system activity: procedural variables.
abstract: Operant conditioning of the sensorimotor rhythm of the human electroencephalogram with time-outs contingent on epileptiform activity reduces epileptic seizure rates in patients whose seizures are not well controlled by medication. A comparison of this procedure with time-out training alone demonstrates that operant conditioning of the sensorimotor rhythm is neither necessary nor sufficient for seizure reduction.
mesh_terms: D001676:Biofeedback, Psychology / Q000502:physiology*; D001921:Brain / Q000503:physiopathology; D003216:Conditioning, Operant / Q000502:physiology*; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology / Q000628:therapy*; D006801:Humans