title: Genetic bases for protein polymorphism in Fundulus heteroclitus (L.).I. Lactate dehydrogenase (Ldh-B), malate dehydrogenase (Mdh-A), glucosephosphate isomerase (Gpi-B), and phosphoglucomutase (Pgm-A).
abstract: Electrophoretic analysis has shown populations of F. heteroclitus to possess variants at four enzyme-coding loci: Ldh-B, Mdh-A, Gpi-B, and Pgm-A. Based on the phenotypic distribution in the F1 generation, each variant segregates as an autosomally inherited codominant allele. A pairwise comparison of the expected phenotypic classes among these loci showed no evidence of strong linkage; however, weak linkage could not be ruled out. Despite the considerable genetic divergence of populations from the geographical extremes of this species, offspring resulting from crosses between individuals from these localities show viabilities similar to those found for crosses of local populations.
mesh_terms: D000818:Animals; D003433:Crosses, Genetic; D004587:Electrophoresis, Agar Gel; D005399:Fishes / Q000235:genetics*; D005956:Glucose-6-Phosphate Isomerase / Q000235:genetics*; D007695:Killifishes / Q000235:genetics*; D007770:L-Lactate Dehydrogenase / Q000235:genetics*; D008291:Malate Dehydrogenase / Q000235:genetics*; D010733:Phosphoglucomutase / Q000235:genetics*; D011110:Polymorphism, Genetic; D013379:Substrate Specificity; D014018:Tissue Distribution
chemical_list: D007770:L-Lactate Dehydrogenase; D008291:Malate Dehydrogenase; D005956:Glucose-6-Phosphate Isomerase; D010733:Phosphoglucomutase