Dopamine potentiates anaphylactic contraction of pulmonary vein of calf.
Isolated strips of pulmonary vein of antigen-sensitized calf contracted to histamine, serotonin and antigen. In the presence of subthreshold concentrations of dopamine (10(-6) M), anaphylactic contractions to antigen were enhanced, whereas responses to histamine and serotonin were not.
D000707:Anaphylaxis / Q000503:physiopathology*; D000818:Animals; D002417:Cattle; D004298:Dopamine / Q000494:pharmacology*; D006632:Histamine / Q000494:pharmacology; D066298:In Vitro Techniques; D011667:Pulmonary Veins; D012701:Serotonin / Q000494:pharmacology; D014661:Vasoconstriction / Q000187:drug effects*
D012701:Serotonin; D006632:Histamine; D004298:Dopamine