On a rabbit hyperlipemia induced by a fungic galactomannane peptide.
I.v. injection into rabbits of a fungic galactomannane peptide isolated from the culture medium of Aspergillus oryzae induced the apparition, 20 h later, of an hypertriglyceridemia, with a concomittant decrease of about 70% of the post-heparin lipoprotein lipase activity. The same effect had been obtained earlier with a carbohydrate-rich fraction purified from a crude papain preparation. The 2 fractions are compared.
D000818:Animals; D001236:Aspergillus oryzae / Q000032:analysis; D002241:Carbohydrates / Q000032:analysis; D006020:Glycopeptides / Q000032:analysis / Q000494:pharmacology; D006949:Hyperlipidemias / Q000139:chemically induced*; D008049:Lipase / Q000037:antagonists & inhibitors; D008351:Mannans; D011817:Rabbits
D002241:Carbohydrates; D006020:Glycopeptides; D008351:Mannans; C018949:galactomannane peptide; D008049:Lipase