title: [Use of new Bulgarian hydrosol vitamin preparations in veterinary medicine].
abstract: Studied were the new Bulgarian hydrosol preparations Hydro-AD3EC, Hydro-AD3EK, and Hydro-EC. Their tolerance was investigated with the use of albino Wistar rats, the resorption and retention (by their liver content) of retinol and d, 1-alfa-tocopherol was investigated in young broiler chickens, the resorption of ascorbic acid was followed up in White English layers, the antihemorrhagic effect of Hydro-AD3EK was studied in rats with experimentally induced hemorrhagic diathesis offering 30 mg ethyl biscoumacetate (pellentan tablets) with the feed. It was found that the oral application of the first three hydrosol preparations to albino rats at the rate of 12.5 cm3/body weight (equal to 10-15 effective doses for birds) did not produce toxic effects. The retinol and d, 1-alfa-tocopherol constituents of AD3EC and AD3EK, given with the drinking water to birds, were well resorbed and were deposited in the liver. Fuller resorption was observed with the use of AD3EC. The ascorbic acid of AD3EC and AD3EK when these were offered per os to adult chickens was resorbed quickly, which was better expressed with AD3EC. AD3EK in oral application to rats produced antihemorrhagic effects. The use of these preparations in a prophylactic scheme with young broilers shortened the fattening period and improved the feed conversion.
mesh_terms: D000042:Absorption; D000284:Administration, Oral; D000818:Animals; D002031:Bulgaria; D002645:Chickens; D003102:Colloids; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical / Q000662:veterinary; D006474:Hemorrhagic Disorders / Q000188:drug therapy / Q000378:metabolism; D051381:Rats; D014730:Veterinary Medicine; D014815:Vitamins / Q000378:metabolism / Q000627:therapeutic use*
chemical_list: D003102:Colloids; D004338:Drug Combinations; D014815:Vitamins
vernacular_title: Prouchvaniia vurkhu prilaganeto na novi bulgarski khidrozolni vitaminni preparati vuv veterinarnata meditsina.