Postmortem findings in three patients treated with intravenous fat emulsions.
Three patients died of intercurrent illness in relation to intravenous nutrition with fat emulsions (20% Intralipid). In two cases, postmortem findings showed milky white, shiny, clotted lumps in the heart, with a fatty acid composition resembling that of fat emulsions. In vitro investigations make it likely that fibrin deposits in hyperlipemic plasma composed the lumps. In two cases, 30- to 50-mu Sudan-positive accumulations were found in the small vessels of the lungs, the cerebrum, and the kidneys.
D000368:Aged; D001344:Autopsy; D005217:Fat Emulsions, Intravenous / Q000009:adverse effects* / Q000032:analysis; D005260:Female; D005337:Fibrin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*
D005217:Fat Emulsions, Intravenous; D005337:Fibrin