[Absorption and oxidation rate of arginine and malate (author's transl)].
Six normal volunteers received L-Arginin and DL-Malat p.o. in order to test absorption and utilisation of these compounds. Both compounds are almost completely reabsorbed from the intestine and then metabolized. Only about 2% of the arginine applied are recovered in the urine. 15% of arginine and 45% of malate applied are metabolized within 8 hours. If absorption is unimpaired oral therapy of hyperammoniemia would require application of the malate-arginine solution for every 3 hours, if constant plasma levels are to be achieved.
D000293:Adolescent; D000328:Adult; D000641:Ammonia / Q000097:blood; D001120:Arginine / Q000378:metabolism* / Q000627:therapeutic use; D006801:Humans; D007408:Intestinal Absorption; D007700:Kinetics; D008293:Malates / Q000378:metabolism* / Q000627:therapeutic use
D008293:Malates; D000641:Ammonia; D001120:Arginine
Untersuchungen zur Resorption und Oxidationsrate von Arginin und Malat.