Candida tropicalis arthritis - assessment of amphotericin B therapy.
A 28 year old male heroin addict developed Candida tropicalis infection of the knee joint in association with candidemia. Assessment of amphotericin B therapy was facilitated by the determination of serum and synovial fluid amphotericin B concentrations using a radiometric bio-assay method. The results indicate that adequate synovial fluid drug levels were achieved with intravenous systemic therapy.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D001170:Arthritis, Infectious / Q000188:drug therapy*; D002177:Candidiasis / Q000188:drug therapy*; D004341:Drug Evaluation; D006801:Humans; D007592:Joint Diseases / Q000188:drug therapy; D007719:Knee Joint; D008297:Male
D000666:Amphotericin B