title: Pyridazino[1,2-a] 1,2,5-triazepines.
abstract: By the condensation of 1,2-di(chloracetyl)piperidazine with primary amines 3-substituted derivatives of 1,5-diketoperhydropyridazino[1,2-a] 1,2,5-triazepine (1--8, Fig. 1) were obtained. Some of them show sedative action at the 25--100 mg/k dosis level and are of low ip toxicity.
mesh_terms: D000818:Animals; D001381:Azepines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D003500:Cyclization; D006993:Hypnotics and Sedatives; D007928:Lethal Dose 50; D051379:Mice; D011724:Pyridazines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity
chemical_list: D001381:Azepines; D006993:Hypnotics and Sedatives; D011724:Pyridazines