[Effect of estradiol on carbohydrate metabolism in the uterine musculature].
The Effect of 7.5 micrograms i.v. 17-beta-oestradiol on the sugar metabolism of the uterine musculature was studied in 180-200 g Wistar rats. The myometrial metabolic reaction consisted of increased glucose phosphorylation, enhanced utilisation of creatine phosphate, and increased production of adenosine triphosphate and creatine phosphate initially, followed by their consumption. The gradual fall in the lactate: pyruvate ratio showed that this stimulation of glycolysis was not occurring in the absence of oxygen.
D000244:Adenosine Diphosphate / Q000378:metabolism; D000249:Adenosine Monophosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D050260:Carbohydrate Metabolism; D004958:Estradiol / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D007275:Injections, Intravenous; D009215:Myometrium / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D010725:Phosphocreatine / Q000378:metabolism; D051381:Rats; D014599:Uterus / Q000378:metabolism*
D010725:Phosphocreatine; D000249:Adenosine Monophosphate; D004958:Estradiol; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate
Effetto dell'estradiolo sul metabolismo glicidico del muscolo uterino.