[Supplementary report on the study of resistance to coumafene in Rattus ratus observed at Marseilles].
A resistance to coumafene has previously been observed among Rattus rattus in a foodstuffs warehouse in the port of Marseille. New tests are here reported. They concern rats captured in two warehouses situated at a distance of 1,000 m. from one another, and separated by a distance approximately similar to that of the first warehouse explored. The experiments which were carried out, although limited in number, have clearly shown a resistance to coumafene administered in high doses in a rat of the first group and in three rats of the second group. There is every reason to fear a resistance extended to all the territories where Rattus rattus are found in the harbour and in the neighbouring regions.
D000818:Animals; D000925:Anticoagulants / Q000008:administration & dosage / Q000494:pharmacology*; D004351:Drug Resistance; D005602:France; D051381:Rats; D012375:Rodent Control / Q000379:methods; D012378:Rodenticides
D000925:Anticoagulants; D012378:Rodenticides
Note complémentaire sur l'étendue de la résistance au coumaféne de Rattus rattus observée a marseille.