Androgen metabolism in the epithelium of the bovine cornea.
The metabolism of [14C]-testosterone and [14C]-androstenedione resp. was investigated in the epithelium of the cow cornea. [14C]-testosterone was converted mainly to androstenedione (48.3%), while conversion to dihydrotestosterone accounted only for 2%. On incubation of androstenedione mainly testosterone was formed (9.8%) and polar, probably hydroxylated, substances (7.6%).
D000735:Androstenedione / Q000378:metabolism*; D000818:Animals; D002250:Carbon Radioisotopes; D002417:Cattle; D003315:Cornea / Q000378:metabolism*; D004848:Epithelium / Q000378:metabolism; D007553:Isotope Labeling; D013739:Testosterone / Q000378:metabolism*; D014316:Tritium
D002250:Carbon Radioisotopes; D014316:Tritium; D013739:Testosterone; D000735:Androstenedione