The use of competitive inhibition of substrate-binding to cytochrome P450 in the determination of spectral dissociation constants for substrates with multiple types of binding, as illustrated with 1-butanol.
D000818:Animals; D001667:Binding, Competitive; D000440:Butanols / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D005036:Ethylmorphine / Q000378:metabolism; D005260:Female; D066298:In Vitro Techniques; D008297:Male; D008433:Mathematics; D051379:Mice; D013053:Spectrophotometry; D013379:Substrate Specificity
D000440:Butanols; D003577:Cytochrome P-450 Enzyme System; D005036:Ethylmorphine