Stimulation of lymphocytes in patients with psoriasis under photochemotherapy. A study of lymphocyte transformation.
Lymphocyte-transformation by phytohaemagglutinine (PHA) was examined in 21 patients with generalized psoriasis during photochemotherapy (PUVA). Lymphocyte-transformation-tests (LTT) were performed before and after 8-methoxypsoralen (8-MOP) medication, before and after the initial irradiation and before and after the first maintenance irradiation four to six weeks later. Spontaneous and PHA-induced lymphocyte-transformation was not altered by 8-MOP alone or in combination with UVA irradiation.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects*; D008297:Male; D008730:Methoxsalen / Q000627:therapeutic use; D008875:Middle Aged; D010778:Photochemotherapy; D010835:Phytohemagglutinins; D011565:Psoriasis / Q000188:drug therapy*
D010835:Phytohemagglutinins; D008730:Methoxsalen