The effect of hypokinesis on blood clotting in rabbits.
In 53 male chinchilla rabbits the effect of 14-day strict immobilization on the blood clotting and myocardial function capacity was studied. Hypercoagulability and enhancement of thrombocytic functional activity were found. The blood platelets of the experimental animals formed larger aggregates than those of the control animals. These changes were accompanied by myocardial ischaemic lesions, proved by electrocardiography.
D000244:Adenosine Diphosphate / Q000494:pharmacology; D000818:Animals; D001772:Blood Cell Count; D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D001792:Blood Platelets; D003094:Collagen / Q000494:pharmacology; D004562:Electrocardiography; D004837:Epinephrine / Q000494:pharmacology; D006400:Hematocrit; D008297:Male; D009068:Movement; D009203:Myocardial Infarction / Q000175:diagnosis / Q000209:etiology; D010973:Platelet Adhesiveness; D010974:Platelet Aggregation / Q000187:drug effects; D011817:Rabbits; D012149:Restraint, Physical
D000244:Adenosine Diphosphate; D003094:Collagen; D004837:Epinephrine