title: Future research--potentially rewarding areas for investigation.
abstract: Further research is still needed for many aspects of hormone replacement therapy in post-menopausal women. The type of regimen to be used, and in it the type of oestrogen, the type of progestogen, the route of administration, and the dose all require further evaluation. Careful investigation will then be needed to determine the effect of the chosen regimen on the presenting symptoms, and also long-term effect on coagulation factors, carbohydrate and lipid metabolism, osteoporosis and endometrial carcinoma. At present there are no definite criteria as to which patients should be chosen for therapy or the duration for which treatment should be given.
mesh_terms: D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D005544:Forecasting; D006801:Humans; D008593:Menopause / Q000187:drug effects*; D011372:Progestins / Q000627:therapeutic use; D012106:Research; D012306:Risk
chemical_list: D004967:Estrogens; D011372:Progestins