title: [Live vaccine against salmonellosis in swine].
abstract: A live vaccine was produced against salmonellosis in pigs, using a mutant strain 3--297 of Salmonella cholerae suis. The vaccine proved fully innocuous at the rate of 1 cm3 to guinea pigs and at 2-5 ml to pigs, and 15 days following injection the vaccinal strains was no longer isolated from the test animals. Guinea pigs injected singly at the rate of 1cm3 of the vaccine and infected on the 12th day with a pathogenic Salmonella cholerae suis strain died up to 12 per cent (the control ones up to 91 per cent). Pigs vaccinated singly or twice at the rate of 2 cm3 and infected on the 20th day (i/v) with a pathogenic strain of Salmonella cholerae suis died up to 14 per cent (the control ones up to 80 per cent).
mesh_terms: D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage* / Q000276:immunology; D004353:Drug Evaluation, Preclinical; D006168:Guinea Pigs; D012475:Salmonella / Q000276:immunology*; D012481:Salmonella Infections, Animal / Q000517:prevention & control*; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control; D013997:Time Factors; D014611:Vaccination / Q000662:veterinary
chemical_list: D001428:Bacterial Vaccines
vernacular_title: Zhiva vaksina sreshtu salmoneloza po svinete.