Digoxin removal from an anephric patient by hemoperfusion over XAD-4.
Removal of digoxin by hemoperfusion over Amberlite XAD-4 was determined in a functionally anephric patient. During four hours of hemoperfusion, 50.45 microgram of digoxin were removed by the column and serum digoxin concentrations decreased by 0.2 ng/ml after the post-hemoperfusion reequilibration was complete.
D004077:Digoxin / Q000097:blood*; D006333:Heart Failure / Q000188:drug therapy; D006464:Hemoperfusion / Q000379:methods*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011137:Polystyrenes; D011145:Polyvinyls; D012117:Resins, Synthetic; D014018:Tissue Distribution
D011137:Polystyrenes; D011145:Polyvinyls; D012117:Resins, Synthetic; D004077:Digoxin