[Squalene and sterols of rat stomach tissue and the effect of acetylsalicylic acid on their content].
The contents of squalene, free and esterified sterols (metastenol, lathosterol, 7-dehydrocholesterol, cholesterol) in tissues of the rat esophageal and glandular stomach were studied in normalcy and under the effect of acetyl salicylic acid. The tissue of different stomach regions differs in the content of squalene, free and esterified sterols. Under the effect of acetyl salicylic acid the content of squalene and free sterols in tissues of the both stomach regions lowers. The amount of esterified sterols rises in the tissue of glandular stomach and lowers in the tissue of esophageal region. The data obtained are discussed taking into account the function of sterols in biological membranes.
D000818:Animals; D001241:Aspirin / Q000494:pharmacology*; D002784:Cholesterol / Q000378:metabolism; D002788:Cholesterol Esters / Q000378:metabolism; D003684:Dehydrocholesterols / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism*; D008297:Male; D008566:Membranes / Q000502:physiology; D051381:Rats; D013185:Squalene / Q000378:metabolism*; D013261:Sterols / Q000378:metabolism* / Q000502:physiology; D013270:Stomach / Q000187:drug effects
D002788:Cholesterol Esters; D003684:Dehydrocholesterols; D013261:Sterols; D013185:Squalene; C001521:lathosterol; D002784:Cholesterol; D001241:Aspirin
Skvalen i steriny tkani zheludka krys i vliianie na ikh soderzhanie atsetilsalitsilovoĭ kisloty.