Spectrophotometric determination of theophylline formulations.
Minophylline (theophylline ethanoate of piperazine) and aminophylline (theophylline ethylenediamine) were determined spectrophotometrically in dosage forms without interference from excipients and/or preservatives. A mixture of minophylline, in about 30-fold concentration, with phenobarbital was assayed for both components with good accuracy and high reproducibility.
D000628:Aminophylline / Q000032:analysis; D004338:Drug Combinations; D008433:Mathematics; D008722:Methods; D010634:Phenobarbital / Q000032:analysis; D010879:Piperazines / Q000032:analysis; D012996:Solutions / Q000032:analysis; D013056:Spectrophotometry, Ultraviolet; D013607:Tablets / Q000032:analysis; D013806:Theophylline / Q000031:analogs & derivatives* / Q000032:analysis
D004338:Drug Combinations; D010879:Piperazines; D012996:Solutions; D013607:Tablets; C023721:acefyllin piperazinate; D000628:Aminophylline; D013806:Theophylline; D010634:Phenobarbital