title: [Thorotrast kidney as a precancerous condition].
abstract: 9 cases of "thorotrast kidney" after retrograde pyelography with reflux are presented. In 6 patients carcinoma of the renal pelvis developed 47--31 years after thorotrast pyelography. Because of this high rate of carcinoma induction, thorotrast kidney must be classified as a precancerous condition with high-rate tumor manifestation. Thorotrast kidney is diagnosed on X-ray by very opaque linear densities following the calices and pyelon. Early ureteronephrectomy is the treatment of choice in unilateral thorotrast kidneys. If uretero-nephrectomy is not possible, the patient should be followed up regularly with urinary cytologic examinations for early detection of malignancy.
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000209:etiology*; D007682:Kidney Pelvis / Q000528:radiation effects; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011230:Precancerous Conditions / Q000209:etiology*; D013911:Thorium Dioxide / Q000009:adverse effects*; D013997:Time Factors; D014567:Urography / Q000009:adverse effects / Q000379:methods
chemical_list: D013911:Thorium Dioxide
vernacular_title: Thorotrastose der Niere als Präkanzerose.