[Suppression of hepatic myeloid metaplasia after irradiation of the spleen in a case of spent polycythemia (author's transl)].
In a case of spent polycythemia after irradiation of the spleen alone (450 rad in 17 sessions and 28 days) the suppression of any hepatic myeloid metaplasia was observed simultaneously with the regression of myelemia and erythroblastemia and the drop in the number of circulating granulomonocytic stem cells. These observations allow to discuss the mode of action of the splenic radiotherapy and the relationship between myeloid metaplasia and the circulating hematopoietic cells (proliferating granulocytic and erythrocytic cells and stem cells).
D001854:Bone Marrow Cells; D006412:Hematopoietic Stem Cells / Q000528:radiation effects; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D011087:Polycythemia Vera / Q000175:diagnosis / Q000532:radiotherapy*; D055728:Primary Myelofibrosis / Q000209:etiology / Q000473:pathology / Q000532:radiotherapy*; D013154:Spleen / Q000528:radiation effects*
Disparition de la métaplasie myéloïde hépatique après radiothérapie splénique d'une splénomégalie myéloïde.