[Evaluation of globular osmotic resistance (GOR) and of the lysis test with glycerol (GLT/50) in the screening of heterozygous thalassemia].
A rapid and simple procedure measuring the rate of hemolysis of 50% of erytrocytes suspended in a standardized glycerol mixture (GLT/50) has been compared with the erytrocyte osmotic fragility to NaCl 0.375% concentration, carried out according to Parpat's method modified, in order to estimate the respective behaviour in the screening of beta-thalassemia trait. The GLT/50 is provided with more selectivity especially between beta-thalassemia trait carriers and other subjects with iron deficiency anemia.
D000747:Anemia, Hypochromic / Q000175:diagnosis; D005990:Glycerol; D006801:Humans; D008403:Mass Screening; D009996:Osmotic Fragility; D013789:Thalassemia / Q000175:diagnosis*
D005990:Glycerol
Valutazione della resistenza globulare osmotica (RGO) e del test di lisi al glicerolo (GLT/50) nello screening della thalassemia eterozigote.