Efficacy of injectable and tablet formulations of praziquantel against mature Echinococcus granulosus.
The efficacy of an injectable formulation of praziquantel (given either intramuscularly or subcutaneously at dose levels of 5 or 8 mg/kg of body weight) and a tablet formulation (5 mg/kg) against mature Echinococcus granulosus tapeworms was studied in experimentally infected dogs. The compound was efficacious (100% clearance) if injected via either route or if administered orally.
D000284:Administration, Oral; D000818:Animals; D000923:Anticestodal Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004443:Echinococcosis / Q000188:drug therapy / Q000662:veterinary*; D007279:Injections, Subcutaneous; D007546:Isoquinolines / Q000008:administration & dosage* / Q000627:therapeutic use; D011719:Pyrazines / Q000008:administration & dosage / Q000627:therapeutic use; D013607:Tablets
D000923:Anticestodal Agents; D007546:Isoquinolines; D011719:Pyrazines; D013607:Tablets