[Enzymes of carbohydrate and lipid metabolism in dependence on age (author's transl)].
The levels of the rat liver enzymes glucose-6-phosphate-dehydrogenase, alpha-glycerophosphate-dehydrogenase and citrate cleavage enzyme decrease between the age groups of 3 and 18 months. The half-life time of these enzymes is uneffected by age and the diminished levels of the enzymes in the liver of old rats can be ascribed to a reduced rate of enzyme synthesis. The half-life time of malic enzyme decreases as a function of age and this increased enzyme destruction may contribute to the diminished malic enzyme level of old rat liver.
D001275:ATP Citrate (pro-S)-Lyase / Q000378:metabolism; D000375:Aging; D000818:Animals; D050260:Carbohydrate Metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D005993:Glycerolphosphate Dehydrogenase / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000201:enzymology*; D051381:Rats
D005993:Glycerolphosphate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D001275:ATP Citrate (pro-S)-Lyase
Enzyme des Kohlenhydrat- und Lipidstoffwechsels in Abhängigkeit vom Alter.