[Electrophoretic and kinetic properties of erythrocyte glucose-6-phosphate dehydrogenase (Gd) in hereditary enzyme deficiency. A new variant of glucose-6-phosphate dehydrogenase : Gd Kremenchug].
A study of the activity of human erythrocyte G-6-PD has been completed on a great number of normal controls, coming from different regions of the USSR. This study has led to the discovery of a new variant of erythrocytic Gd, which was named "Kremenchug" from the origin of the patient. This new Gd, has a very low Km for G-6-P, and has a greater affinity for 2-deoxyglucose-6-phosphate. The maximal activity versus the pH of the medium is also characteristic of this new Gd.
D000328:Adult; D002648:Child; D004586:Electrophoresis; D004912:Erythrocytes / Q000201:enzymology*; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis* / Q000235:genetics; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000201:enzymology / Q000235:genetics*; D006801:Humans; D007700:Kinetics; D008297:Male; D009154:Mutation
D005954:Glucosephosphate Dehydrogenase
Etude des propriétés électrophorétiques et cinétiques de la glucose-6-phosphate déshydrogénase (Gd) d'érythrocytes dans les déficits héréditaires de l'enzyme. Description d'une nouvelle variante de glucose-6-phosphate déshydrogénase : la Gd Kremenchug.