Response to doxorubicin in hairy cell leukaemia.
A case of hairy cell leukaemia (HCL) treated by single-agent chemotherapy after the failure of splenectomy is reported. The patient was treated with doxorubicin 50 mg on 4 occasions over an 8-day period. After 2 weeks of profound pancytopenia, substantial blood and bone marrow improvement ensued. This case demonstrates that HCL may in some case be treated successfully by intensive chemotherapy.
D000328:Adult; D004317:Doxorubicin / Q000008:administration & dosage / Q000627:therapeutic use*; D004341:Drug Evaluation; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000188:drug therapy*; D008297:Male; D013156:Splenectomy
D004317:Doxorubicin