[Photochemotherapy and cataract formation].
According to the literature combined treatment with 8-MOP and UVA has induced ocular damage in animals. Similar changes in humans on photochemotherapy have not yet been reported and therapeutic doses are considerably lower than the doses that proved toxic for the animal eye. The present paper reviews pertinent literature on the subject and discusses the conditions under which photochemotherapy for psoriasis seems acceptable in view of present day knowledge.
D000818:Animals; D002386:Cataract / Q000139:chemically induced*; D006168:Guinea Pigs; D006801:Humans; D007908:Lens, Crystalline / Q000187:drug effects; D008730:Methoxsalen / Q000627:therapeutic use / Q000633:toxicity; D051379:Mice; D010778:Photochemotherapy / Q000009:adverse effects*; D011565:Psoriasis / Q000188:drug therapy*
D008730:Methoxsalen
Photochemotherapie und Kataraktbildung.