title: Influence of whole-body mechanical vibration on altitude convulsion threshold.
abstract: Altitude convulsion threshold was used for determining the maximal hypoxic tolerance of the mouse during whole-body transverse vibration. Elevation of the lung weight-body weight ratio was taken as evidence of lung edema. It was observed that vibration of 8 cps at 2 mm displacement (peak to peak) or 4 cps at 4 mm displacement did not affect the altitude convulsion threshold and the said ratio. On the other hand, vibration of 12 cps at 2 mm displacement, or 8 and 12 cps at 4 mm displacement caused an increase in a altitude convulsion threshold as well as lung edema. The possible mechanism of these changes is discussed.
mesh_terms: D000222:Adaptation, Physiological; D000531:Altitude; D000818:Animals; D001835:Body Weight; D000860:Hypoxia / Q000503:physiopathology*; D008168:Lung / Q000473:pathology / Q000503:physiopathology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains / Q000502:physiology; D009929:Organ Size; D011654:Pulmonary Edema / Q000503:physiopathology; D012640:Seizures / Q000209:etiology*; D014732:Vibration / Q000009:adverse effects*