Measurement of fasting and postprandial plasma VIP in man.
A specific radioimmunoassay has been developed capable of detecting 1.5 pmol VIP/l plasma with 95% confidence. The antisera employed reacted most avidly with whole VIP, partly with C terminal, but not with N terminal fragments. In 110 healthy fasting volunteers plasma VIP concentrations were estimated to lie between 0.5 and 21 pmol/l (median 1.7). No significant change was seen after ingestion of a standard test meal.
D000293:Adolescent; D000328:Adult; D005215:Fasting; D005502:Food; D005768:Gastrointestinal Hormones / Q000097:blood*; D006801:Humans; D011863:Radioimmunoassay; D014660:Vasoactive Intestinal Peptide / Q000097:blood*
D005768:Gastrointestinal Hormones; D014660:Vasoactive Intestinal Peptide