title: [Zinc and enzymes in the synovial fluid and blood in various types of rheumatism].
abstract: It appears that in rheumatoid arthritis and, to a lesser extent, in the other forms of inflammatory rheumatism, the level of zinc in the blood serum is lowered, whereas synovial zinc is increased. In the synovial fluid, there is a very significant correlation between enzyme activity and the concentration of zinc. Practical experiments aimed at demonstrating in vitro the action of zinc on lacticodeshydrogenase, acid phosphatase, lysozyme and beta-glucuronidase did not produce the anticipated results and do not explain the metabolic disorders of zinc seen during inflammatory rheumatisms.
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000378:metabolism*; D004798:Enzymes / Q000097:blood; D005966:Glucuronidase / Q000378:metabolism*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D009113:Muramidase / Q000378:metabolism*; D013582:Synovial Fluid / Q000032:analysis* / Q000201:enzymology; D015032:Zinc / Q000097:blood / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D004798:Enzymes; D007770:L-Lactate Dehydrogenase; D000135:Acid Phosphatase; D009113:Muramidase; D005966:Glucuronidase; D015032:Zinc
vernacular_title: Zinc et enzymes dans le liquide synovial et le sang au cours de rhumatismes divers.