HLA antigens in gouty patients.
Lymphocytes from 26 patients with primary gout were typed for eighteen antigens from A and B loci. An increased "relative risk" of the disease was established in patients carrying antigen HLA-B14, but the correlation is not sufficient for using HLA typing as a diagnostic tool in the gout. Nevertheless HLA-B14 seems to be one of the genetic factors which predispose to the appearance of the articular lesions.
D000328:Adult; D005787:Gene Frequency; D006073:Gout / Q000276:immunology*; D006680:HLA Antigens / Q000032:analysis* / Q000235:genetics; D006801:Humans; D008297:Male; D012306:Risk
D006680:HLA Antigens