[Ergospirometric studies on patients with diabetes mellitus and the effect of biguanides on physical performance].
24 diabetic patients had submaximal exercise testing before, and 4 days after, biguanide treatment. Biguanide treatment resulted in a significantly decreased exercise capacity. This is explained by increased anaerobic energy production, which results in a decrease of the performance of an individual.
D001645:Biguanides / Q000009:adverse effects* / Q000627:therapeutic use; D003920:Diabetes Mellitus / Q000188:drug therapy*; D006801:Humans; D008297:Male; D005082:Physical Exertion / Q000187:drug effects*
D001645:Biguanides
Ergospirometrische Untersuchungen bei Patienten mit Diabetes mellitus und der Einfluss der Biguanide auf die körperliche Leistungsfähigkeit.