Microbiological 1,2-dehydration of microcrystalline epihydrocortisone and its 21-acetate.
A method is described for obtaining epiprednisolone and its 21-acetate by means of microbiological 1,2-dehydration by a culture of Mycobacterium globiforme 193. The substrate, epihydrocortisone or its 21-acetate, is added in the form of a microcrystalline suspension at a concentration of 25-100 g/liter medium.
D003461:Crystallography; D006854:Hydrocortisone / Q000031:analogs & derivatives* / Q000378:metabolism*; D009161:Mycobacterium / Q000378:metabolism*; D011239:Prednisolone / Q000031:analogs & derivatives / Q000096:biosynthesis
D011239:Prednisolone; D006854:Hydrocortisone