"Glial bundles" in the spinal cord late after paralytic anterior poliomyelitis.
"Glial bundles" in the proximal portion of the anterior spinal roots, identical to those in Werdnig-Hoffmann disease, were observed in 3 patients many years after attacks of acute paralytic anterior poliomyelitis. These structures should therefore be considered a nonspecific astrocytic reaction secondary to the destruction of motor neurons and their axons rather than a malformation specific for Werdnig-Hoffman disease.
D001253:Astrocytes; D006801:Humans; D009133:Muscular Atrophy / Q000235:genetics; D011051:Poliomyelitis / Q000473:pathology*; D013116:Spinal Cord / Q000473:pathology*; D013577:Syndrome