title: Nuclear fragmentation in colon carcinoma cells.
abstract: The nuclei of the epithelial cells of well differentiated adenocarcinoma of the large intestine show characteristic appendages, the nucleotesimals, connected with the main nucleus by lamellar bridges. We interpret this phenomenon as being the result of a hitherto unknown type of amitosis that permits rapid cancer growth in spite of a low mitotic index.
mesh_terms: D000230:Adenocarcinoma / Q000648:ultrastructure*; D002467:Cell Nucleus / Q000648:ultrastructure; D002843:Chromatin / Q000648:ultrastructure; D003110:Colonic Neoplasms / Q000648:ultrastructure*; D006801:Humans; D009685:Nuclear Envelope / Q000648:ultrastructure
chemical_list: D002843:Chromatin