title: [Interaction among the trace elements zinc, copper and iron after depletion and repletion of dairy cows with zinc].
abstract: Imbalances in the supply with trace elements may be caused by the excessive administration of one or several elements or the insufficient administration in relation to other trace elements. This article deals with the interactions between the trace elements zinc and copper resp. zinc and iron under the conditions of the insufficient supply with Zn (6 mg per kg dry matter of the fodder) and the supply according to the demand with other trace elements (14 mg copper resp. 83 mg iron per dry matter of the fodder). For this purpose we investigated the copper, iron and zinc content of the milk and the serum of cows that were first depleted of zinc through a semi-synthetic zinc deficiency diet and then repleted with extra allowances of zinc. The closest connections exist between the copper and zinc content of the milk. Thus extreme Zn-deficiency feeding conditions the decreased Zn-content on the one hand and increased Cu-content on the other. In contrast to this, the cows' Zn-excretion in the milk increases after Zn-repletion whereas the Cu-content decreases. This shows a distinctly negative correlation. A loose connection could only be detected for the Cu- and Zn-content of the serum. Though the Zn-content changed considerably in dependence on the Zn-supply, the Cu-content remained largely uninfluenced. The Fe-content of both milk and serum shows no interaction with the nutritive Zn-supply. Only after 19 test weeks of extreme Zn-deficiency could a slight increase of the Fe-concentration be indicated.
mesh_terms: D000818:Animals; D002417:Cattle; D003300:Copper / Q000097:blood / Q000378:metabolism*; D005260:Female; D007501:Iron / Q000097:blood / Q000378:metabolism*; D008892:Milk / Q000378:metabolism*; D011247:Pregnancy; D015032:Zinc / Q000172:deficiency / Q000378:metabolism* / Q000627:therapeutic use
chemical_list: D003300:Copper; D007501:Iron; D015032:Zinc
vernacular_title: Wechselwirkungen zwischen den Spurenelementen Zink, Kupfer und Eisen nach Zinkdepletion und -repletion von Milchkühen.