[Familial periodic paralysis with hypokaliemia, hyperaldosteronism and extracellular vacuolization (author's transl)].
The observation of a 20 years old patient with a periodic paralysis is reported. During a crisis induced by 20 U of insulin and 150 g of glucose, transient hyperaldosteronism was found and the muscular biopsy performed in the left biceps brachii, disclosed vacuoles with a double membrane. The significance of these findings is discussed.
D000328:Adult; D005947:Glucose / Q000009:adverse effects; D006801:Humans; D006929:Hyperaldosteronism / Q000139:chemically induced / Q000150:complications*; D007008:Hypokalemia / Q000150:complications*; D007328:Insulin / Q000009:adverse effects; D008297:Male; D008854:Microscopy, Electron; D009132:Muscles / Q000473:pathology*; D009469:Neuromuscular Junction / Q000473:pathology; D010245:Paralyses, Familial Periodic / Q000139:chemically induced / Q000150:complications* / Q000473:pathology; D010375:Pedigree; D014617:Vacuoles
D007328:Insulin; D005947:Glucose
Paralysie périodique familiale avec hypokaliémie, hyperaldostéronisme et vacuolisation extra-cellulaire.