title: Aggressive histological features of keratoacanthoma.
abstract: Thirty-nine keratoacanthomas from 35 patients have been studied, six of which showed perineural, and one vascular, invasion. Thus far, their aggressive histological behavior has not been paralleled by a similar clinical course. However, continued close follow-up is essential.
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007636:Keratoacanthoma / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology*