title: Neurotoxicity of styrene in occupational and experimental exposure.
abstract: Occupational styrene exposure caused an increased frequency of abnormal electroencephalograms which correlated to degree of exposure. No dose-response relationship could be shown concerning a slowing of nerve conduction velocities in workers exposed to styrene. Experimental exposure of rats to 300 ppm of styrene caused a transient increase in the nerve conduction velocity in 6 weeks, but in a comparison to control rats no difference was found in measurements performed on rats exposed for  8  and 11 weeks.
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects; D004569:Electroencephalography; D004781:Environmental Exposure; D006801:Humans; D008297:Male; D008333:Mandelic Acids / Q000652:urine; D009046:Motor Neurons / Q000187:drug effects; D009422:Nervous System Diseases / Q000139:chemically induced*; D009431:Neural Conduction / Q000187:drug effects*; D009787:Occupational Medicine; D051381:Rats; D013343:Styrenes / Q000633:toxicity*
chemical_list: D008333:Mandelic Acids; D013343:Styrenes