title: Diffuse infantile fibromatosis.
abstract: A boy 15 months old with diffuse infantile fibromatosis in the thigh is reported. A rapidly growing tumor in the right thigh was the only clinical manifestation, suggesting a malignant soft tissue tumor. Macroscopically, the lesion in the medial vastus muscle with an illdefined border gave a pepper and salt appearance. Histologically, the lesion was characterized by an abnormal proliferation of fibroblasts accompanied by some fibrosis, infiltration of chronic inflammatory cells, formation of lymphoid follicles, proliferation of capillaries and the presence of a small number of mature fat cells. No evidence of recurrence is found at present one and half years after operation.
mesh_terms: D005350:Fibroma / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D012983:Soft Tissue Neoplasms / Q000473:pathology*; D013848:Thigh