Synthesis of substituted 7-hydroxy-5H-1.3.4-thiadiazolo[3.2-a]pyrimidin-5-ones with anticipated antimicrobial activity.
The synthesis of some derivatives of substituted 7-hydroxy-5H-1.3.4-thiadiazolo[3.2-a]pyrimidin-5-ones, as possible antimicrobial agents, is described. The IR, NMR and MS data of representative members of the series are reported. Proposed common fragmentation pathways for this series are deduced.
D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000494:pharmacology
D000890:Anti-Infective Agents; D011743:Pyrimidines