An approach for the in vitro screening of drugs for activity against leprosy.
Slow growing strains of mycobacteria isolated from leprous tissues present a characteristic resistance pattern to antibacterial agents that is comparable to drug sensitivity of M. leprae in man.
D004353:Drug Evaluation, Preclinical / Q000379:methods; D004352:Drug Resistance, Microbial; D007917:Leprostatic Agents; D007918:Leprosy / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D009161:Mycobacterium / Q000187:drug effects*
D007917:Leprostatic Agents