[Dermatological incompatibility reaction to X5Cr-Ni-Mo 18.10 steel implants in animal experiments].
Metal allergy is surveyed in detail. Especially the development of eczema by means of metallic implantates containing chromium or nickel. The results from two series of experiments on guinea-pigs are presented. The first series proves that after preceding sensibilization by potassium bichromate or nickel-II-sulfate eczemas may be induced in the guinea-pig by X 5 Cr Ni Mo 18.10 steel implantates. Positive skin reactions in the patch test prove the possibility of sensibilization by X 5 Cr Ni Mo 18.10 steel in a second series of animals preoperatively negative.
D000818:Animals; D002857:Chromium / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology*; D004485:Eczema / Q000209:etiology*; D006168:Guinea Pigs; D009532:Nickel / Q000009:adverse effects*; D010328:Patch Tests; D013232:Steel
D002857:Chromium; D013232:Steel; D009532:Nickel
Dermatologische Univerträglichkeitsreaktionen durch X 5 Cr Ni Mo 18.10 Stahl-Implantate im Tierexperiment.