GLC determination of butylated hydroxyanisole in human plasma and urine.
A highly sensitive and specific GLC method was developed for the analysis of butylated hydroxyanisole, a commonly used antioxidant. Concentrations below 100 ng/ml could be detected in human plasma and urine. Preliminary pharmacokinetic studies demonstrated that, upon administration of 100 mg po, butylated hydroxyanisole was quickly absorbed and removed from the plasma with a high degree of intersubject variability.
D000328:Adult; D000840:Anisoles / Q000032:analysis*; D002083:Butylated Hydroxyanisole / Q000032:analysis* / Q000097:blood / Q000652:urine; D002849:Chromatography, Gas; D006801:Humans; D007700:Kinetics; D008297:Male; D008722:Methods
D000840:Anisoles; D002083:Butylated Hydroxyanisole