[Experimental study on cattle anemia due to immune antibodies. 3. Effects of anemia on the liver].
A characterisation in greater detail was undertaken of haemolytic anaemia caused by immune antibody and its effects on the liver of young cattle. Bioptate follow-up tests were applied to two animals, while bromosulphalein half-life and SGOT activity were determined in seven. Centrolobular liver necrosis was not reproducible. Some moderate liver cell damage was histologically detected. Certain responses recorded from the reticulohistiocytary part of the liver were interpreted as a consequence of aggravated damage to erythrocytes. The above moderate liver cell damage failed to produce statistically secured rises in bromosulphalein half-life nor SGOT activity.
D000744:Anemia, Hemolytic, Autoimmune / Q000662:veterinary*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D006207:Half-Life; D008099:Liver / Q000473:pathology*; D008107:Liver Diseases / Q000209:etiology; D013448:Sulfobromophthalein / Q000378:metabolism
D013448:Sulfobromophthalein; D001219:Aspartate Aminotransferases
Experimentelle Untersuchungen zur immunantikörperbedingten Anämie des Rindes. 3. Mitteilung: Zu den Auswirkungen der Anämie auf die Leber.