Synthesis of some 11H-indolo[3,2-c][1,8]naphthyridines.
The preparation of some 11H-indolo[3,2-c] [1,8]naphthyridines (V), having oxygen functions at positions 3 or 3 and 10 or 3 and 8, as in steroidal active compounds, is described. Compounds (V) were obtained using the Fisher indole synthesis. The preparation of the parent nucleus: 11H-indolo [3,2-c] [1,8]naphthyridines (V n) is also described. Some compounds were subjected to pharmacological screening, but none was found to be significantly active.
D000818:Animals; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology; D008722:Methods; D009287:Naphthyridines / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats
D007211:Indoles; D009287:Naphthyridines