title: Syntheses in the group of aminoguanidine derivatives with immunosuppressive and cytostatic properties.
abstract: A number of new derivatives of amino-, nitroamino- and diaminoguanidine (I, II, III) were synthetized. The course of the reactions was studied and the structure of new compounds obtained was confirmed. Some of them exhibited strong immunosuppressive and cytostatic activities, especially compounds: IV, VI, VII, VIII and IX.
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006146:Guanidines / Q000138:chemical synthesis*; D007166:Immunosuppressive Agents / Q000138:chemical synthesis*; D013329:Structure-Activity Relationship
chemical_list: D000903:Antibiotics, Antineoplastic; D006146:Guanidines; D007166:Immunosuppressive Agents