title: Effects of C apoproteins on the activity of endothelium-bound lipoprotein lipase.
abstract: Rat apoprotein C-II activated the hydrolysis of triacylglycerol in apoprotein-depleted chylomicrons by lipoprotein lipase in vitro and in the perfused rat heart. Apoproteins C-I and C-III-3 inhibited the hydrolysis of the triacylglycerol moiety in intact and apoprotein C-II-re-activated chylomicrons in vitro, but had no effect on the hydrolysis in situ.
mesh_terms: D000818:Animals; D001059:Apoproteins / Q000494:pharmacology*; D002914:Chylomicrons / Q000378:metabolism; D004727:Endothelium / Q000201:enzymology; D006321:Heart / Q000187:drug effects; D066298:In Vitro Techniques; D008071:Lipoprotein Lipase / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D014280:Triglycerides / Q000378:metabolism
chemical_list: D001059:Apoproteins; D002914:Chylomicrons; D014280:Triglycerides; D008071:Lipoprotein Lipase