title: Effect of intra-arterial CO2 insuffflation on occlusive arterial disease in the lower leg.
abstract: Twenty patients with a mean age of 79 years were followed over a period of 6 months after intra-arterial insufflation of CO2 in the lower extremity. All patients had severe peripheral occlusive arterial disease caused by atherosclerosis and were scheduled for amputation. A significant increase of the distal perfusion pressure was obtained in the majority of the cases resulting in pain relief and healing of ulcers and gangrenes.
mesh_terms: D000368:Aged; D001157:Arterial Occlusive Diseases / Q000628:therapy*; D001794:Blood Pressure; D002245:Carbon Dioxide / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005263:Femoral Artery; D005528:Foot / Q000098:blood supply; D005533:Foot Dermatoses / Q000628:therapy; D005734:Gangrene / Q000628:therapy; D006801:Humans; D007269:Injections, Intra-Arterial / Q000009:adverse effects / Q000295:instrumentation; D007511:Ischemia / Q000628:therapy; D007866:Leg / Q000098:blood supply*; D008297:Male; D059408:Pain Management; D014456:Ulcer / Q000628:therapy
chemical_list: D002245:Carbon Dioxide