The reversal of the oxygen difference between arterial blood and cerebrospinal fluid in chronic, exacerbated respiratory insufficiency.
The relationship between PaO2 and PCSFO2 (along with other acid-base parameters) was studied in patients with long-lasting respiratory failure. These patients exhibited a highly significant reversal of the normal relationship, i.e. their PCSF O2 was invariably higher, than PaO2. It is suggested that this reflects a mechanism protecting the brain against hypoxia.
D000208:Acute Disease; D000368:Aged; D001158:Arteries; D002908:Chronic Disease; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000097:blood / Q000134:cerebrospinal fluid; D008297:Male; D010100:Oxygen / Q000097:blood* / Q000134:cerebrospinal fluid*; D010313:Partial Pressure; D012131:Respiratory Insufficiency / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*
D010100:Oxygen