Carboxymethyl-selenopyruvic acid as the product of the oxidative deamination of carboxymethyl-selenocysteine.
CMSeC labeled with 14C in the carboxymethyl moiety was incubated with snake venom L-aminoacid oxidase. As the product of the reaction only one ketoacid was detected, which retained all the radioactivity of the oxidized substrate. This clearly shows that no breakdown of the C-Se bond of CMSeC occurs during its oxidation, and confirms previously reported data indicating that the ketoacid arising from CMSeC is CMSeP.
D000594:Amino Acid Oxidoreductases / Q000378:metabolism; D002233:Carbocysteine / Q000031:analogs & derivatives* / Q000378:metabolism; D003545:Cysteine / Q000031:analogs & derivatives*; D003641:Deamination; D010084:Oxidation-Reduction; D011773:Pyruvates / Q000302:isolation & purification / Q000378:metabolism*; D012643:Selenium / Q000378:metabolism
D011773:Pyruvates; D002233:Carbocysteine; D000594:Amino Acid Oxidoreductases; D012643:Selenium; D003545:Cysteine