Renal prostaglandins in renal hypertensive dogs.
1. Hypertension produced in two-kidney Goldblatt dogs was accompanied by a transient fluid retention, reaching a maximum 4 days after clamping. 2. Prostaglandin E and F concentrations in venous blood from the intact kidney also rose transiently, showing a maximum by the fifth day. 3. The rise in prostaglandin release from the intact kidney may be related to the fluid retention.
D000818:Animals; D004285:Dogs; D005260:Female; D006439:Hemodynamics; D006977:Hypertension, Renal / Q000097:blood* / Q000503:physiopathology; D007668:Kidney / Q000378:metabolism*; D011458:Prostaglandins E / Q000097:blood* / Q000378:metabolism; D011460:Prostaglandins F / Q000097:blood* / Q000378:metabolism; D012082:Renal Veins; D012083:Renin / Q000097:blood; D013997:Time Factors
D011458:Prostaglandins E; D011460:Prostaglandins F; D012083:Renin