title: Four deaths due to intravenous injection of cocaine.
abstract: Cocaine is a potent psychotropic drug that alters mood and behavior by stimulating the central nervous system. Deaths from abuse of cocaine are relatively rare. Most such deaths appear to be related to the intravenous injection of the drug. Acute fatal cocaine intoxication is characterized by headache, cold sweats, rapid pulse, tremors and nausea, followed by convulsions, unconsciousness and death. The prime mode of death appears to be respiratory paralysis, secondary to the effects of cocaine on the medullary portion of the brain. This paper presents four deaths due to acute cocaine intoxication following intravenous injection. Blood concentrations of cocaine were 0.11, 0.37, 0.36 and 0.75 mg/dl.
mesh_terms: D000328:Adult; D002849:Chromatography, Gas; D003042:Cocaine / Q000008:administration & dosage / Q000032:analysis / Q000506:poisoning*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D013058:Mass Spectrometry; D019966:Substance-Related Disorders / Q000150:complications*
chemical_list: D003042:Cocaine