Limbal immunopathology of Mooren's ulcer.
A patient with a progressive Mooren's ulcer of the cornea was successfully treated utilizing a peritomy with limbal conjunctival excision and cryotherapy. The limbal conjunctiva contained a band of IgG beneath the epithelium as well as complement and fibrin in the wall of small blood vessels. This implies Mooren's ulcer is an immune mediated process.
D000328:Adult; D003176:Complement C3; D003315:Cornea / Q000473:pathology; D003320:Corneal Ulcer / Q000276:immunology* / Q000473:pathology; D005337:Fibrin; D006801:Humans; D007074:Immunoglobulin G; D008297:Male
D003176:Complement C3; D007074:Immunoglobulin G; D005337:Fibrin