Blindness secondary to steroid injections into the nasal turbinates.
Two cases of inadvertent intra-arterial injection into the anterior turbinates for treatment of allergic rhinitis resulted in retrograde flow of methylprednisolone acetate in the ophthalmic artery. Both patients demonstrated embolization of the retinal circulation, and one of the choroidal circulation as well. Visual outcome was favorable, although one patient showed a permanent paracentral scotoma. Fundus photographs clearly showed intra-arterial obstruction of arterioles that cleared within several days. Precautions can be taken for the prevention of this complication.
D000328:Adult; D001766:Blindness / Q000139:chemically induced*; D002829:Choroid / Q000098:blood supply; D004617:Embolism / Q000139:chemically induced; D005260:Female; D006801:Humans; D007269:Injections, Intra-Arterial; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects*; D009296:Nasal Cavity; D012171:Retinal Vessels
D008775:Methylprednisolone