[Hypoparathyroidism in adults (author's transl)].
The authors studied the clinical characteristics of primary and post-operative hypoparathyroidism in 39 patients. Laboratory follow-up data were compared under two different treatment programs using either AT 10 or 25 Hydroxycholecalciferol (25 OHCC). Clinical analysis revealed the atypical characteristics of primary hypoparathyroidism. From a therapeutic standpoint, AT 10 and 25 OHCC were equally effective in provoking a return to normal plasma calcium levels, except in complex cases of vitamin D resistance. 25 OHCC proved much easier to manipulate than at 10 and offered a higher security with respect tothe risk of hypercalcemia. The biological activity of 25 OHCC seems to differ from that of AT 10, especially regarding phosphorus metabolism.
D000328:Adult; D002118:Calcium / Q000097:blood / Q000652:urine; D004097:Dihydrotachysterol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use*; D007011:Hypoparathyroidism / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D010710:Phosphates / Q000097:blood; D012621:Seasons; D013965:Thyroidectomy
D006887:Hydroxycholecalciferols; D010710:Phosphates; D004097:Dihydrotachysterol; D002118:Calcium
L'insuffisance parathyroïdienne de l'adulte.