The effect of supplemental vitamin E on vitamin A serum levels in cystic fibrosis.
Effects of the ingestion of vitamin E with vitamin A on the serum levels of these vitamins and the urinary creatine to creatinine ratios of 18 children with cystic fibrosis disease of the pancreas (CF) was studied. After the daily ingestion for two months of a specially prepared capsule containing 5000 IU vitamin A palmitate and 100 mg d alpha-tocopherol acetate in aqueous dispersible form there was a significant increase in vitamin A as well as vitamin E levels of serum taken 3 1/2 hr postprandially. Creatine to creatinine ratios in single voiding of urine decreased.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003401:Creatine / Q000652:urine; D003404:Creatinine / Q000652:urine; D003550:Cystic Fibrosis / Q000188:drug therapy* / Q000378:metabolism / Q000652:urine; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D014801:Vitamin A / Q000097:blood* / Q000627:therapeutic use; D014810:Vitamin E / Q000097:blood / Q000627:therapeutic use*
D014801:Vitamin A; D014810:Vitamin E; D003404:Creatinine; D003401:Creatine