Effect of limiting post-shock pulmonary edema on mortality from bacterial pneumonia.
Dogs were subjected to hemorrhagic shock and then resuscitated according to physiological parameters. Randomly selected dogs received a sublethal dose of intratracheal microorganisms. In comparing the results with those previously reported from our laboratory, in which animals received an 85% greater resuscitation of Ringer's lactate, it appears that pulmonary edema in the post-shock contaminated state can be limited. Furthermore, through minimization of pulmonary edema, pulmonary defenses appear to be improved and mortality from infection reduced.
D000818:Animals; D004285:Dogs; D011014:Pneumonia / Q000150:complications / Q000401:mortality / Q000517:prevention & control*; D011552:Pseudomonas Infections / Q000150:complications / Q000517:prevention & control; D001261:Pulmonary Atelectasis / Q000517:prevention & control; D011654:Pulmonary Edema / Q000150:complications / Q000401:mortality / Q000517:prevention & control*; D012151:Resuscitation; D012771:Shock, Hemorrhagic / Q000150:complications* / Q000401:mortality / Q000628:therapy