[Effect of several cholinomimetic and anticholinesterase substances on the somatic musculature of the nematode Ascaris suum].
On the basis of discrete concentration--effect curves, quantitative evaluation of the effect of acetylcholine, propionylcholine, suberylcholine and carbacholine upon the strips of the spinal muscle of Ascaris was made. Anticholinesterase drugs, eserine and phosphacol, exhibit weak potentiation of the effect of acetycholine (by 2--6 times). The results obtained are discussed in relation to cholinoreceptive properties of muscles in higher animals.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001200:Ascaris; D002217:Carbachol / Q000494:pharmacology; D002800:Cholinesterase Inhibitors / Q000494:pharmacology*; D004347:Drug Interactions; D009132:Muscles / Q000187:drug effects*; D010277:Parasympathomimetics / Q000494:pharmacology*; D010830:Physostigmine / Q000494:pharmacology; D011950:Receptors, Cholinergic / Q000187:drug effects
D002800:Cholinesterase Inhibitors; D010277:Parasympathomimetics; D011950:Receptors, Cholinergic; D002217:Carbachol; D010830:Physostigmine; D000109:Acetylcholine
Deĭstvie nekotorykh kholinomimeticheskikh i antikholinésteraznykh veshchestv na somaticheskuiu muskulaturu nematody Ascaris suum.