Effects of a long-acting progestin on reproductive function in female mice.
The duration of activity of a long-acting progestin, medroxyprogesterone acetate, was compared using three tests for progestational activity: the induction of stromal mitosis in the endometrium, implantation of blastocysts and inhibition of ovulation. The duration of activity was similar in each test and was longer when higher doses were given.
D000818:Animals; D010064:Embryo Implantation / Q000187:drug effects; D004717:Endometrium / Q000166:cytology / Q000187:drug effects; D005260:Female; D008525:Medroxyprogesterone / Q000494:pharmacology*; D051379:Mice; D008938:Mitosis / Q000187:drug effects; D010060:Ovulation / Q000187:drug effects; D011247:Pregnancy; D012098:Reproduction / Q000187:drug effects*; D013997:Time Factors
D008525:Medroxyprogesterone