Computer simulation of calcium-induced myotonia.
In an extensive research project on myotonia, the ionic mechanisms which are at the basis of the phenomenon of calcium-induced myotonia have been taken into consideration. A mathematical model of a muscle fibre was constructed to demonstrate the possibility that anomalous values of the membrane permeability to Calcium ions have an active part in the genesis of myotonia.
D000200:Action Potentials; D000818:Animals; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism*; D002463:Cell Membrane Permeability; D003201:Computers; D006801:Humans; D007477:Ions; D008954:Models, Biological; D009119:Muscle Contraction; D009132:Muscles / Q000378:metabolism* / Q000648:ultrastructure; D009222:Myotonia / Q000378:metabolism*; D012508:Sarcolemma / Q000378:metabolism / Q000502:physiology
D007477:Ions; D002118:Calcium