[Electron microscopic studies on phagocytosis of iron particles by smooth muscle cells in experimental vascular injury induced by intravascular application of direct current (author's transl)].
In experimentally induced arterial thrombosis of minipigs caused by intravascular application of direct current iron deposits deriving from the steel wire electrode are found. Intimal proliferation can be observed 6 weeks after induction of thrombosis. Iron deposits are phagocytized by modified smooth muscle cells participating in intimal proliferation. These findings indicate that smooth muscle cells under certain conditions can realize functions of macrophages.
D000818:Animals; D005260:Female; D007501:Iron / Q000378:metabolism*; D008264:Macrophages; D008297:Male; D008854:Microscopy, Electron; D009130:Muscle, Smooth / Q000378:metabolism / Q000648:ultrastructure*; D010587:Phagocytosis; D013552:Swine; D013927:Thrombosis / Q000473:pathology*
D007501:Iron
Elektronenmikroskopische Untersuchungen zur Phagozytose von Eisenpartikeln durch glatte Muskelzellen bei experimenteller Gefässwandschädigung durch intravasale Gleichstromeinwirkung.