Dissolution of gallstones in hamsters by 3-hydroxy-3-methylglutaric acid.
Addition of 0.05--0.20% of 3-hydroxy-3-methylglutaric acid to a lithogenic hamster diet resulted in a marked reduction in the incidence of gallstones in hamsters.
D000818:Animals; D002635:Chenodeoxycholic Acid / Q000627:therapeutic use; D002769:Cholelithiasis / Q000209:etiology / Q000517:prevention & control*; D006224:Cricetinae; D005977:Glutarates / Q000627:therapeutic use*; D006880:Hydroxy Acids / Q000627:therapeutic use*
D005977:Glutarates; D006880:Hydroxy Acids; D002635:Chenodeoxycholic Acid