[Effect of the degree of short stature on the type of response to tests of pituitary growth hormone reserve].
Two HGH (insulin and L-Dopa) stimulating tests were performed at time interval on 65 subjects with short stature (SDs between -2 and -4.5 according to Tanner) and on 18 control subjects, in order to study the influence of short stature degree on the HGH behaviour during the stimulating tests. The results obtained show that: 1. Statistically the short stature degree does not affect the response to HGH stimulating tests. 2. Two tests are necessary to avoid erroneous diagnosis of dwarfism caused by lack of HGH. 3. No response to HGH stimulating tests in subjects with normal stature may prove a discrepancy between the hormone measured radioimmunologically and its biological action.
D001827:Body Height; D002648:Child; D002675:Child, Preschool; D004393:Dwarfism, Pituitary / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D013006:Growth Hormone / Q000097:blood / Q000172:deficiency / Q000378:metabolism*; D006801:Humans; D007328:Insulin; D007980:Levodopa; D008297:Male; D010901:Pituitary Function Tests; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology*; D013268:Stimulation, Chemical
D007328:Insulin; D007980:Levodopa; D013006:Growth Hormone
Influenza del grado di deficit staturale sul tipo di risposta ai tests di riserva ipofisaria per l'ormone della crescita.