In vivo metabolism of N-alkylamphetamines in the rat--the effect of N-alkyl chain length on oxidation of the aromatic ring.
In vivo metabolism of N-alkylated amphetamines in the rat produced 4-hydroxy- and 4-hydroxy-3-methoxy-metabolites. The relative quantities of the phenolicmetabolites formed were dependent upon the length of the N-alkyl substituent.
D000662:Amphetamines / Q000378:metabolism*; D000818:Animals; D002849:Chromatography, Gas; D006900:Hydroxylation; D010084:Oxidation-Reduction; D051381:Rats; D013329:Structure-Activity Relationship
D000662:Amphetamines