title: DNA-binding properties of nuclear matrix proteins.
abstract: Mouse nuclear matrix proteins, examined by a filter assay, were found to bind to DNA. There was no preference for homologous mouse compared to heterologous E. coli DNA. Competition assays showed a preference for AT-rich DNA and of the 4 single-stranded homopolymers there was a preference for poly(dT). These observations are consistent with the possibility that the matrix may play a role in the formation of AT-rich chromomeres (G-bands).
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism*; D004247:DNA / Q000378:metabolism*; D004277:DNA, Single-Stranded; D066298:In Vitro Techniques; D051379:Mice; D008970:Molecular Weight; D011119:Polynucleotides; D011485:Protein Binding; D013936:Thymidine / Q000378:metabolism
chemical_list: D004277:DNA, Single-Stranded; D011119:Polynucleotides; D004247:DNA; D013936:Thymidine