NMR studies of sustained release methadone tablets.
NMR studies for the identification of methadone in sustained release tablets is conducted. Up-field shifts of the N-methyl and phenyl groups of the compound were observed. These changes indicate an increased lipid solubility and therefore better absorptivity of the drug in the current form.
D003692:Delayed-Action Preparations; D009682:Magnetic Resonance Spectroscopy; D008691:Methadone / Q000032:analysis*; D013607:Tablets / Q000032:analysis
D003692:Delayed-Action Preparations; D013607:Tablets; D008691:Methadone