title: Cogan's syndrome with arthritis and aortic insufficiency.
abstract: A young man with nonsyphilitic keratitis and vestibulo-auditory dysfunction (Cogan's syndrome) and a recurrent febrile illness has been observed over a 10 year period. The systemic manifestations have included a splenic abscess vasculitis, pericarditis, aortic valvulitis, and mono-articular inflammatory arthritis.
mesh_terms: D000038:Abscess / Q000150:complications; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001022:Aortic Valve Insufficiency / Q000150:complications*; D001170:Arthritis, Infectious / Q000150:complications* / Q000188:drug therapy; D006319:Hearing Loss, Sensorineural / Q000150:complications*; D006801:Humans; D007634:Keratitis / Q000150:complications*; D007719:Knee Joint; D007759:Labyrinth Diseases / Q000150:complications*; D008297:Male; D010406:Penicillins / Q000627:therapeutic use; D013158:Splenic Diseases / Q000150:complications; D013577:Syndrome
chemical_list: D000305:Adrenal Cortex Hormones; D010406:Penicillins