The development and use of a test to identify resistance to the anticoagulant difenacoum in the Norway rat (Rattus norvegicus).
Feeding tests were carried out in the laboratory to obtain basic data on the susceptibility of wild Norway rats to difenacoum. The results were used to derive a standard test procedure for the identification of difenacoum resistance in warfarin-susceptible and resistant rats. Details are given of tests on rats from suspected difenacoum-resistant infestations on farms.
D015110:4-Hydroxycoumarins / Q000633:toxicity*; D000818:Animals; D004361:Drug Tolerance; D004739:England; D051379:Mice; D051381:Rats; D012375:Rodent Control; D012378:Rodenticides / Q000633:toxicity; D014859:Warfarin / Q000633:toxicity*
D015110:4-Hydroxycoumarins; D012378:Rodenticides; D014859:Warfarin