Synthesis of some 4-hydroxypiperazine and N.N.-dibenzylhydroxylamine esters with potential local anaesthetic activity.
In the synthetic approach to some new local anaesthetics, it was desirable to prepare esters of N1-methyl-N4-hydroxypiperazine and N.N-dibenzylhydroxylamine. Their local anaesthetic activity testing is in progress.
D000779:Anesthetics, Local / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D006898:Hydroxylamines / Q000138:chemical synthesis* / Q000494:pharmacology; D010879:Piperazines / Q000138:chemical synthesis* / Q000494:pharmacology
D000779:Anesthetics, Local; D006898:Hydroxylamines; D010879:Piperazines