Chronic reduction of renal mass: glomerular morphometry by electron microscopy.
Changes of glomerular volume in rats were measured up to 21 weeks following subtotal nephrectomy, using morphometric methods. A linear increase of glomerular volume was observed between 2 and 21 weeks after subtotal nephrectomy. This progressive increase in glomerular volume may reflect compensatory hemodynamic changes leading to an increased single nephron glomerular filtration rate.
D000818:Animals; D001485:Basement Membrane; D005260:Female; D005919:Glomerular Filtration Rate; D007678:Kidney Glomerulus / Q000502:physiology / Q000648:ultrastructure*; D008433:Mathematics; D009392:Nephrectomy; D051381:Rats