Modification of hyperglycaemic effect of angiotensin by indomethacin.
Effect of angiotensin II was studied on blood sugar level in dogs. Angiotensins given by intravenous route caused a marked rise in blood sugar level. Indomethacin and propranolol significantly influence the changes in blood sugar level induced by angiotensin. It is suggested that the hyperglycaemia induced by angiotensin appears to be mediated by facilitation of adrenaline and prostaglandin release.
D000804:Angiotensin II / Q000008:administration & dosage / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D004285:Dogs; D005260:Female; D007213:Indomethacin / Q000494:pharmacology*; D007275:Injections, Intravenous; D008297:Male; D011433:Propranolol / Q000494:pharmacology; D013997:Time Factors
D001786:Blood Glucose; D000804:Angiotensin II; D011433:Propranolol; D007213:Indomethacin