[Differences in the polypeptide composition of virulent and avirulent strains of Newcastle disease virus in reproduction in chick embryo fibroblast culture].
The loss of the capacity for secondary infection of the cells in reproduction of avirulent Newcastle disease virus strains in chick embryo fibroblast cultures was found. This loss was shown to be associated with changes in the polypeptide composition of the virions. In virions of the avirulent Queensland strain incapable of infection CEF cultures an additional polypeptide was found with molecular mass of 67,000 daltons which was lacking in virions of the virulent Beaudette strain and corresponded to F0 protein of paramyxoviruses.
D000818:Animals; D002478:Cells, Cultured; D002642:Chick Embryo; D003588:Cytopathogenic Effect, Viral; D005347:Fibroblasts / Q000382:microbiology; D006020:Glycopeptides / Q000032:analysis*; D008970:Molecular Weight; D009522:Newcastle disease virus / Q000032:analysis* / Q000472:pathogenicity; D010455:Peptides / Q000032:analysis*; D014764:Viral Proteins / Q000032:analysis*; D014771:Virion / Q000032:analysis*; D014774:Virulence; D014779:Virus Replication
D006020:Glycopeptides; D010455:Peptides; D014764:Viral Proteins
Razlichiia v polipeptidnom sostave virulentnykh i avirulentnykh shtammov virusa bolezni N'iukasla pri reproduktsii v kul'ture fibroblastov kuringo embriona.