Production of xanthomegnin and viomellein by species of Aspergillus correlated with mycotoxicosis produced in mice.
By using thin-layer chromatography and infrared spectroscopy, xanthomegnin and viomellein have been isolated and identified from species of the Aspergillus ochraceus group. A correlation was established between the occurrence of these fungal quinones in the fungal cultural products and the ability of these products to induce mycotoxicosis in mice. In addition, a method was employed to estimate the amount of xanthomegnin and viomellein produced by the fungi.
D000818:Animals; D001230:Aspergillus / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D005260:Female; D008297:Male; D051379:Mice; D009183:Mycotoxins / Q000096:biosynthesis* / Q000633:toxicity; D009285:Naphthoquinones / Q000096:biosynthesis* / Q000633:toxicity; D013045:Species Specificity; D013055:Spectrophotometry, Infrared
D009183:Mycotoxins; D009285:Naphthoquinones; C009688:xanthomegnin; C013735:viomellein