title: [Amyotrophic lateral sclerosis with degeneration of thalamus and substantia nigra (author's transl)].
abstract: A 40-year-old man suffering from amyotrophic lateral sclerosis with symmetrical degeneration of the thalamus and the substantia nigra is reported. The distribution pattern of the  thalamic degeneration in the present case was characteristic in that the Nucleus centralis was the severest affected of the thalamic nuclei. As far as we know, there is no such case of amyotrophic lateral sclerosis in the literature. Nosologically, this case may represent a form of combined heredosystemic degeneration.
mesh_terms: D000328:Adult; D000690:Amyotrophic Lateral Sclerosis / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D013378:Substantia Nigra / Q000473:pathology*; D013787:Thalamic Nuclei / Q000473:pathology; D013788:Thalamus / Q000473:pathology*
vernacular_title: Myatrophische Lateralsklerose kombiniert mit Degeneration im Thalamus und der Substantia nigra.