Rod-cone dysplasia in the collie.
Rod-cone dysplasia in the Collie was studied. Night blindness developed early (6 wk) and progressed to nearly total blindness by 1 year of age. Tapetal hyper-reflectivity, vessel attenuation, and optic nerve pallor were clinically evident by 6 months of age. Electroretinography demonstrated markedly reduced retinal response as early as 16 days of age. The results of selective breedings conformed to a single recessive pattern of inheritance.
D000818:Animals; D004283:Dog Diseases / Q000235:genetics / Q000503:physiopathology; D004285:Dogs; D004596:Electroretinography; D005260:Female; D008297:Male; D010786:Photoreceptor Cells / Q000473:pathology; D012162:Retinal Degeneration / Q000235:genetics / Q000503:physiopathology / Q000662:veterinary*