[Morphological findings in RES modified by methylpalmitate].
Intravenous injections of methylpalmitate (MP) suspension in extreme doses of 3 g/kg of the animal's weight were seen developing in rats after 24 hours manifestations of phagocytosis in the cells of the red pulp of spleen followed by red pulp necrosis. Smaller doses of 1-1.5 g MP/kg of b.w. caused no pronounced morphological changes in the animal's organs.
D000818:Animals; D007275:Injections, Intravenous; D008099:Liver / Q000166:cytology; D008297:Male; D012157:Mononuclear Phagocyte System / Q000166:cytology / Q000187:drug effects*; D010168:Palmitates / Q000008:administration & dosage / Q000494:pharmacology*; D010169:Palmitic Acids / Q000494:pharmacology*; D051381:Rats; D013154:Spleen / Q000166:cytology
D010168:Palmitates; D010169:Palmitic Acids
Morfologické nálezy pri ovlivnĕní resu metylpalminátem.