[Influence of small bowel resections on some aspects of digestive secretions in rat (author's transl)].
Some aspects of the digestive secretions both in intact rats (control group) and in rats with resection of 50% and 80% of the small intestine starting from ileocecal valve have been studied. In every animal, the volume of duodenal content, total content of bile salts and amylasic activity have been analysed under the following experimental conditions: fasting, feeding with two diets containing 4% and 20% of fat, and intravenous injections of pancreozymin (2 UI/kg). Total content of bile salts and amylasic activity decrease in resected rats under fasting and feeding. This decrease is greater when larger portions of the intestine are removed. Rats injected with pancreozymin react in a similar way. The amylasic activity decrease in the resected rats indicates a pancreatic hypofunction caused by the resection and cannot be compensated by administration of pancreozymin. Measurements of seric cholesterol show that a 50% resection causes a decrease form normal levels and a 80% resection makes it significant.
D000681:Amylases / Q000032:analysis; D000818:Animals; D001647:Bile Acids and Salts / Q000032:analysis; D002784:Cholesterol / Q000032:analysis; D004386:Duodenum / Q000378:metabolism*; D005260:Female; D007419:Intestinal Secretions / Q000032:analysis* / Q000187:drug effects; D007421:Intestine, Small / Q000601:surgery*; D008297:Male; D010179:Pancreas / Q000502:physiology*; D010194:Pancreatin / Q000494:pharmacology; D051381:Rats
D001647:Bile Acids and Salts; D010194:Pancreatin; D002784:Cholesterol; D000681:Amylases
Influencia de las resecciones intestinales en la rata sobre algunos aspectos de las secreciones digestivas.