Cerebrospinal fluid acid-base balance in patients with severe injuries living at an altitude of 1 660 metres.
Cerebrospinal fluid (CSF) acid-base balance in 40 control subjects and 40 patients with head injuries was studied at an altitude of 1 660 m. The patients with head injuries showed a significantly lower CSF pH associated with a fall in CSF bicarbonate and an elevation of CSF lactic acid. The cause of these observations is unclear, but it is proposed that this may be related to the relative hypoxaemia associated with an altitude of 1 660 m.
D000137:Acid-Base Imbalance / Q000097:blood / Q000134:cerebrospinal fluid*; D000531:Altitude; D006259:Craniocerebral Trauma / Q000134:cerebrospinal fluid*; D006801:Humans