[1.3-Dipolar cycloaddition products of 8-azidotetrazol[1,5a][1,8]naphthyridines with alkynes].
A series of new 1,2,3-triazol derivatives, obtained by reaction of 8-azidotetrazol[1,5-a][1,8]naphthyridine with alkynes, is described. Some of the tested compounds showed activity against hypoxia in mice.
D000480:Alkynes; D000818:Animals; D003500:Cyclization; D000860:Hypoxia / Q000188:drug therapy; D008722:Methods; D051379:Mice; D009287:Naphthyridines; D014230:Triazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000480:Alkynes; D009287:Naphthyridines; D014230:Triazoles
Cicloaddizione 1,3-dipolare dell'8-azidotetrazolo[1,5-a][1,8]naftiridina ad alchini.