title: Adult respiratory distress syndrome precipitated by massive salicylate poisoning.
abstract: Pulmonary oedema has been reported in severe cases of acetyl salicylic acid (ASA) poisoning. Liberal use of intravenous fluids, to establish a forced diuresis, is usually thought to be the precipitating cause. A case of severe ASA poisoning and respiratory failure was found to have increased pulmonary vascular resistance and signs of intravascular hypercoagulability. The patient recovered rapidly on mechanical ventilation with a positive endexpiratory pressure of 18 cm H2O and systemic steroids.
mesh_terms: D001241:Aspirin / Q000506:poisoning*; D001777:Blood Coagulation; D002245:Carbon Dioxide / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D012128:Respiratory Distress Syndrome / Q000097:blood / Q000139:chemically induced*
chemical_list: D002245:Carbon Dioxide; D001241:Aspirin; D010100:Oxygen