Generalized pustular psoriasis precipitated by lithium carbonate.
Precipitation of generalized pustular psoriasis was manifested in a patient with previously stable psoriasis vulgaris following lithium carbonate therapy for manic-depressive psychosis. Methotrexate toxicity was observed during the acute stage of the illness, and photochemotherapy was the successful treatment. Further pustulation occurred when lithium carbonate therapy was reintroduced.
D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy; D005260:Female; D006801:Humans; D008094:Lithium / Q000009:adverse effects* / Q000627:therapeutic use; D008727:Methotrexate / Q000627:therapeutic use; D008730:Methoxsalen / Q000627:therapeutic use; D010778:Photochemotherapy; D011565:Psoriasis / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology
D008094:Lithium; D008730:Methoxsalen; D008727:Methotrexate