title: Collagen sponge for leg ulcers.
abstract: Collagen sponge, reconstituted from bovine tendon, provides a porous matrix for the permeation of fibroblasts and capillaries and on theoretical grounds it should be ideal for stimulating granulation tissue in deep leg ulcers. A preliminary study in six patients has suggested that a collagen sponge dressin enhanced granulation, but subsequent re-epithelialization over the reconstituted collagen tended to be slower than usual.
mesh_terms: D000287:Administration, Topical; D000368:Aged; D003094:Collagen; D005260:Female; D006097:Granulation Tissue; D006801:Humans; D007871:Leg Ulcer / Q000628:therapy*; D008875:Middle Aged
chemical_list: D003094:Collagen