Effect of gum Arabic on aminopyrine demethylation in rats.
Stimulation of aminopyrine demethylation induced in rats by oral or i.p. administration of phenobarbital was partially inhibited in animals receiving daily treatments of 2 x 200 mg/kg gum Arabic p.o.
D000045:Acacia; D000632:Aminopyrine / Q000378:metabolism*; D000818:Animals; D003640:Dealkylation; D005079:Excipients / Q000494:pharmacology*; D005260:Female; D014677:Pharmaceutical Vehicles / Q000494:pharmacology*; D010634:Phenobarbital / Q000494:pharmacology; D011134:Polysaccharides / Q000494:pharmacology*; D051381:Rats
D005079:Excipients; D014677:Pharmaceutical Vehicles; D011134:Polysaccharides; D000632:Aminopyrine; D010634:Phenobarbital