[Non-steroidal anti-inflammatory agents. V. Optically active 4-biphenylyloxybutyric and 4-biphenylylglycolic acids].
The synthesis and the resolution of the enantiomers of (+/-)2-(4-biphenylyl)-4-oxybutyric and (+/-)4-(4-biphenylyl)-2-oxybutyric acids and the resolution of the enantiomers of (+/-)2-(4-biphenylyl)-2-oxybutyric and (+/-)4-biphenylylglycolic acids are described. The potassium salts of each enantiomer were submitted to preliminary assays of antiphlogistic activity.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis*; D002087:Butyrates / Q000138:chemical synthesis* / Q000494:pharmacology; D004487:Edema / Q000503:physiopathology; D006016:Glycolates / Q000138:chemical synthesis* / Q000494:pharmacology; D008297:Male; D051381:Rats; D013237:Stereoisomerism
D000893:Anti-Inflammatory Agents; D002087:Butyrates; D006016:Glycolates
Antiinfiammatori non steroidei. Nota V - Acidi 4-bifenililossibutirrici e 4-bifenililglicolici otticamente attivi.