title: Efficiency of the determinant method of estimating gene frequencies in three allelic models.
abstract: Efficiency of three different methods: Bernstein's, maximum likelihood and determinant method were compared. A relative efficiency calculated as a ratio of variances of estimators was used for the comparison. It was shown that the determinant method is almost as efficient for estimating of recessive gene frequency as the method of maximum likelihood, and more efficient than the Bernstein's method.
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics; D000483:Alleles; D005787:Gene Frequency; D005826:Genetics, Medical; D006801:Humans; D008722:Methods
chemical_list: D000017:ABO Blood-Group System