title: Inhibition of kidney tubule induction by charged polymers.
abstract: Charged polymers, known to alter cell surface characteristics, reversibly inhibit the intercellular communication required in kidney tubule induction. This effect seems to be a function of their charge density. It is suggested that this effect is due to the formation of a molecular barrier between the interacting cell surfaces.
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects*; D002809:Chondroitin Sulfates / Q000494:pharmacology; D046508:Culture Techniques; D003911:Dextrans / Q000494:pharmacology; D004627:Embryonic Induction / Q000187:drug effects*; D006493:Heparin / Q000494:pharmacology; D007684:Kidney Tubules / Q000187:drug effects* / Q000196:embryology / Q000378:metabolism; D051379:Mice; D011107:Polylysine / Q000494:pharmacology; D011108:Polymers / Q000494:pharmacology*
chemical_list: D003911:Dextrans; D011108:Polymers; D011107:Polylysine; D006493:Heparin; D002809:Chondroitin Sulfates