Arterial and venous blood pressure and blood flow following femoral angiography with a new non-ionic contrast medium. An experimental investigation in dogs.
At femoral angiography in dogs the effects of a new non-ionic contrast medium (C29) were compared with those of one non-ionic medium (metrizamide) and one ionic medium (meglumine/sodium diatrizoate) in current use. In the leg subjected to angiography the pressure gradient over the peripheral vessels decreased and the femoral blood flow increased. The changes induced by the ionic medium were significantly greater than those induced by metrizamide and C29, whereas no significant difference between the two non-ionic media was recorded.
D000818:Animals; D001555:Benzene Derivatives / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D001810:Blood Volume / Q000187:drug effects; D003287:Contrast Media / Q000494:pharmacology*; D003974:Diatrizoate Meglumine / Q000494:pharmacology; D004285:Dogs; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging*; D008297:Male; D008793:Metrizamide / Q000494:pharmacology; D011859:Radiography; D012039:Regional Blood Flow / Q000187:drug effects; D012965:Sodium Chloride / Q000494:pharmacology; D014690:Venous Pressure / Q000187:drug effects
D001555:Benzene Derivatives; D003287:Contrast Media; D003974:Diatrizoate Meglumine; D012965:Sodium Chloride; D008793:Metrizamide