Effects of enhanced coronary flow during cardiopulmonary bypass: development of myocardial edema.
Coronary blood flow, left ventricular diastolic stiffness, ventricular water content and ventricular thiocyanate space were investigated in empty fibrillating and empty beating dog hearts during cardiopulmonary bypass. In empty fibrillating hearts coronary blood flow was considerably enhanced even at levels of normal perfusion pressure. A close correlation was demonstrated between enhanced coronary flow, left ventricular diastolic stiffness, tissue water content and thiocyanate space.
D000818:Animals; D001786:Blood Glucose; D002302:Cardiac Output; D002315:Cardiopulmonary Bypass; D003326:Coronary Circulation; D004285:Dogs; D004489:Edema, Cardiac / Q000209:etiology*; D006333:Heart Failure / Q000209:etiology*; D006352:Heart Ventricles / Q000503:physiopathology; D009994:Osmolar Concentration; D013861:Thiocyanates / Q000502:physiology
D001786:Blood Glucose; D013861:Thiocyanates