title: Transit time of a radionuclide bolus through inferior vena cava.
abstract: The effect of an intrinsic block or extrinsic pressure on blood flow through the inferior vena cava (IVC) was studied after rapid injection of 99mTc-pertechnetate or 99mTc-phytate into the femoral vein. Peak-to-peak transit time (PTT) between the curves generated at IVC origin and over the cardiac blood pool was measured in twelve normal patients (PTT = 2.0 +/- 0.7 s) and six patients clinically suspected of circulatory impediment through the IVC (PTT = 3.0 to 30.0 s). PTT measurements augmented the information obtained from sequential scintiphotos of IVC circulation. It is felt that this may be a more objective parameter for follow-up of patients having a progressive, primary disease of this vessel.
mesh_terms: D001775:Blood Circulation; D003201:Computers; D006801:Humans; D007275:Injections, Intravenous; D008722:Methods; D011877:Radionuclide Imaging; D013667:Technetium / Q000008:administration & dosage / Q000378:metabolism*; D013997:Time Factors; D014652:Vascular Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging* / Q000503:physiopathology
chemical_list: D013667:Technetium