title: Red cell glucose-6-phosphate dehydrogenase deficiency and haemoglobin variants among ten endogamous groups of Maharshtra and West Bengal.
abstract: Over 900 individuals from ten endogamous groups in the Indian states of Maharashtra and West Bengal were studied for G-6-PD deficiency and haemoglobin variants. The incidence of G-6-PD varied from nil to 17.3%, while that of Hb-S varied from nil to 22.3%. In general, the tribal populations of Maharashtra are characterized by the presence of a high incidence of both Hb-S and G-6-PD deficiency. The caste Hindus showed an absence of Hb-S and rather low G-6-PD deficiency. Immigrant Parsis possessed the highest incidence of G-6-PD deficiency (17.3%).
mesh_terms: D005787:Gene Frequency; D014644:Genetic Variation; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000235:genetics*; D006454:Hemoglobins / Q000235:genetics*; D006801:Humans; D007194:India
chemical_list: D006454:Hemoglobins