title: An experimental study of the correction of gastroesophageal reflux by gastroplasty.
abstract: The rationale and efficacy of gastroplasty in controlling gastroesophageal reflux were studied by manometry and cinefluorography in the dog. The pressure in a 7 by 3 centimeter gastric tube, constructed from the lesser curvature of the stomach and interposed between the esophagus and the stomach, was 3.6 +/- 1.0 centimeters higher than in the stomach. When abdominal compression was applied, the pressures were similar in the tube and the adjacent stomach, 19.0 +/- 4.0 and 19.4 +/- 4.0 centimeters, and free reflux was demonstrated between the two. When the gastric fundus was wrapped around the gastroplasty tube, its resting pressure was 13.1 +/- 0.5 centimeters higher than gastric pressure. During abdominal compression, the pressure in the gastric tube increased to 23.0 +/- 0.6 centimeters suggesting a flutter-valve arrangement that produced an effective antireflux barrier. These data suggest that gastroplasty can be an effective antireflux method only when combined with fundic wrap.
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D004943:Esophagogastric Junction / Q000601:surgery*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D008365:Manometry; D010779:Photofluorography; D011312:Pressure; D011708:Pylorus / Q000601:surgery; D013270:Stomach / Q000601:surgery*; D014628:Vagotomy