Myoclonus in Alzheimer disease. A confusing sign.
Myoclonus in association with dementia of later adult life has been considered almost pathognomonic of Creutzfeldt-Jakob disease. However, myoclonus may also be seen with Alzheimer disease, and when the myoclonus occurs as an early manifestation of Alzheimer disease, distinction from Creutzfeldt-Jakob disease may prove difficult.
D000368:Aged; D000544:Alzheimer Disease / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis; D003704:Dementia / Q000150:complications*; D003937:Diagnosis, Differential; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D008297:Male; D009207:Myoclonus / Q000209:etiology*; D009454:Neurofibrils / Q000473:pathology