Herpes gestations with identical lesions in the newborn. Passive transfer of the disease?
Cutaneous lesions of herpes gestation is developed in a newborn on the fifth day of life and disappeared spontaneously after three weeks. The immunologic phenomena were analogous in the mother and child. No circulating or in vivo-bound immunoglobulins were demonstrated, but components 3 and 4 of complement were present at the basement membrane zone. We discuss a possible passive transfer of the disease to the newborn, and a supposedly pathogenetic role of immunologic phenomena in herpes gestationis.
D000328:Adult; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000276:immunology / Q000635:transmission*; D008431:Maternal-Fetal Exchange; D006559:Pemphigoid Gestationis / Q000276:immunology / Q000635:transmission*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D011414:Properdin / Q000032:analysis; D012872:Skin Diseases, Vesiculobullous / Q000635:transmission*
D003176:Complement C3; D003181:Complement C4; D011414:Properdin