Clinical evaluation of freeze-dried bone allografts in periodontal osseous defects.
Freeze-dried cortical bone allografts of a fine particle size were implanted into wide three-wall, two-wall, one-wall, combination, and furcation defects. Of the 97 defects treated, 23 manifested complete bone regeneration; 39 showed greater than 50%; and 24, less than 50% osseous repair. Twelve defects failed to demonstrate any bony regeneration, of which nine were furcation involvements. From the preliminary data available, there is strong evidence which indicates that freeze-dried bone allografts have definite potential as grafting  material in certain periodontal osseous defects. However, final determination must await the outcome of a larger number of cases and also histologic evidence.
D000328:Adult; D000539:Alveolar Process / Q000502:physiology; D000543:Alveoloplasty; D016025:Bone Transplantation; D005260:Female; D005612:Freeze Drying; D006801:Humans; D008297:Male; D008875:Middle Aged; D010510:Periodontal Diseases / Q000601:surgery*; D014021:Tissue Preservation; D014184:Transplantation, Homologous