title: Capping of concanavalin A- or ricin-binding sites does not influence phagocytosis in polymorphonuclear leukocytes.
abstract: Rabbit polymorphonuclear leukocytes (PMNs) were capped with territin-conjugated concanavalin A or ricin, and then allowed to phagocytose yeast cells. Phagocytic activity and lectin distribution were determined by ultrastructural morphometry. Capped PMNs were found to phagocytose as efficiently as control PMNs, and always to ingest the particles with a lectin-free portion of their plasma membrane. This clearly indicates that concanavalin A- and ricin-binding sites of the PMN membrane are not involved in the recognition and phagocytosis of yeast particles.
mesh_terms: D000818:Animals; D008854:Microscopy, Electron; D009504:Neutrophils / Q000502:physiology*; D010587:Phagocytosis; D010940:Plant Proteins / Q000378:metabolism*; D011817:Rabbits; D011952:Receptors, Concanavalin A / Q000378:metabolism*; D011955:Receptors, Drug / Q000378:metabolism*; D012276:Ricin / Q000378:metabolism*; D012441:Saccharomyces cerevisiae
chemical_list: D010940:Plant Proteins; D011952:Receptors, Concanavalin A; D011955:Receptors, Drug; D012276:Ricin