[Membranoproliferative glomerulonephritis and mycoplasma infection].
Two children presented with an acute mycoplasma infection associated with a significant increase of antistreptolysin level. A severe nephropathy occurred, rapidly resulting in renal failure with histologic lesions of membrano-proliferative glomerulonephritis. Both patients had persisting low complement levels with low C3 and normal C4. The relationship between mycoplasma and streptococcal infections and the abnormality of complement and the renal disease is discussed.
D000989:Antistreptolysin / Q000032:analysis; D001485:Basement Membrane / Q000276:immunology; D002648:Child; D003176:Complement C3 / Q000032:analysis / Q000172:deficiency; D005260:Female; D005455:Fluorescent Antibody Technique; D005921:Glomerulonephritis / Q000150:complications* / Q000276:immunology; D006801:Humans; D008171:Lung Diseases / Q000150:complications; D009175:Mycoplasma Infections / Q000150:complications*; D013290:Streptococcal Infections / Q000150:complications
D003176:Complement C3; D000989:Antistreptolysin
Glomérulonéphrite membrano-proliférative et maladie mycoplasmique