A computer program for life table regression analysis with time dependent covariates.
This paper presents a computer program for analyzing time-dependent covariables in survival studies by the life table regression model described by Holford [3]. Basically, life table regression incorporates the elements of regression and the life table into a single model. Regression parameters are estimated by the method of maximum likelihood using the Newton-Raphson iterative procedure. The program provides two methods for testing hypotheses concerning regression coefficients, namely the standard normal deviate test and a Wald statistic based on the first and second derivatives of the log likelihood. Residual plots are provided to assess the fit of the model to the data.
D000206:Actuarial Analysis; D003201:Computers; D006801:Humans; D008136:Longevity; D008954:Models, Biological; D009026:Mortality; D012044:Regression Analysis; D013223:Statistics as Topic; D013997:Time Factors