title: Long survival after renal transplantation in man.
abstract: The indications for transplantation, complications, management and results in 127 consecutive patients who had received renal transplants between October 1960 and December 1974 are presented. In 2 cases the donor was an identical twin, in 22 a living relative other than a twin, in 2 an unrelated individual in whom nephrectomy was performed for therapeutic reasons and in 101 a cadaver. At the end of the period under review there were 37 patients alive with grafts which had functioned for 6 months or more; of these, 28 had survived for more than 2 years, 13 for more than 5 years, 6 for more than 8 years and 2 for more than 12 years. Thirty-four patients were employed or doing routine housework or receiving full-time education. One patient fathered a child 4 years after transplantation; another gave birth to a healthy infant 3 years after transplantation.
mesh_terms: D000293:Adolescent; D000328:Adult; D000961:Antilymphocyte Serum / Q000627:therapeutic use; D002102:Cadaver; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection; D006680:HLA Antigens; D006650:Histocompatibility Testing; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007165:Immunosuppression Therapy; D007239:Infections / Q000209:etiology; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000209:etiology; D011183:Postoperative Complications; D011241:Prednisone / Q000627:therapeutic use; D014019:Tissue Donors; D014184:Transplantation, Homologous; D014652:Vascular Diseases / Q000209:etiology
chemical_list: D000961:Antilymphocyte Serum; D006680:HLA Antigens; D011241:Prednisone