[Chronic lathyrism, prolonged hyperlipidic diet, and atheroma in the rat].
Deep, constant, extensive atherosclerosis can be experimentally induced on rats that are atheroresistant. Two main factors are involved in this experimentation; parietal alteration following chronic intoxication with BAPN (9 weeks) and a metabolic factor with hyperlipidic diet, but this metabolic damage should be sustained for a long time (40 weeks).
D000629:Aminopropionitrile / Q000494:pharmacology*; D000818:Animals; D001013:Aorta, Thoracic / Q000378:metabolism / Q000648:ultrastructure; D001161:Arteriosclerosis / Q000139:chemically induced* / Q000473:pathology; D002908:Chronic Disease; D004036:Diet, Atherogenic; D004195:Disease Models, Animal; D007842:Lathyrism; D050356:Lipid Metabolism; D051381:Rats; D013997:Time Factors
D000629:Aminopropionitrile
Lathyrisme chronique, régime hyperlipidique prolongé et athérome chez le rat