Nonspecific immunosuppression induced in mice with killed Pasteurella haemolytica in Freund's complete adjuvant.
Killed Pasteurella haemolytica type I in combination with Freund's complete adjuvant, induced suppression of murine primary response to SRBC. The suppression could be adoptively transferred with spleen cells depleted of T or B lymphocytes and was best expressed when viable cells were transferred. Some normal rabbit serum has the ability to nullify immunosuppressive effects of the transferred cells.
D000818:Animals; D000917:Antibody Formation; D005260:Female; D005620:Freund's Adjuvant / Q000494:pharmacology*; D006462:Hemolytic Plaque Technique; D007165:Immunosuppression Therapy; D008297:Male; D051379:Mice; D010325:Pasteurella / Q000276:immunology*
D005620:Freund's Adjuvant