title: Normal human tissues contain RNA and antigens related to infectious adenovirus type 2.
abstract: Normal human tissues have been found to contain RNA which hybridises with four regions of the adenovirus type 2 genome, including one which contains the transforming gene(s) of this virus. The RNAs have also been extracted from gorilla organs, but not from those of chickens, suggesting that they are a feature of all normal higher primate tissues. Serological test suggest that these homologous RNAs are translated into proteins connected with essentially normal and virus-infected cell functions.
mesh_terms: D000260:Adenoviruses, Human / Q000235:genetics* / Q000276:immunology; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D003429:Cross Reactions; D005260:Female; D005814:Genes, Viral; D006071:Gorilla gorilla / Q000382:microbiology; D006801:Humans; D008099:Liver / Q000382:microbiology; D009693:Nucleic Acid Hybridization; D010920:Placenta / Q000382:microbiology*; D011247:Pregnancy; D012367:RNA, Viral / Q000032:analysis*; D014018:Tissue Distribution; D014764:Viral Proteins / Q000276:immunology
chemical_list: D000956:Antigens, Viral; D012367:RNA, Viral; D014764:Viral Proteins