title: Selective disadvantage of non-functional protein synthesis in Escherichia coli.
abstract: Comparison of growth rates of isogenic strains that synthesize varying levels of beta-galactosidase during continuous culture on non-inducing medium indicates that synthesis of low levels of non-functional protein has a small but possibly significant effect upon growth rate.
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis*; D005075:Biological Evolution; D004926:Escherichia coli / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism*; D005696:Galactosidases / Q000096:biosynthesis; D007785:Lactose / Q000096:biosynthesis; D009154:Mutation; D009876:Operon
chemical_list: D001426:Bacterial Proteins; D005696:Galactosidases; D007785:Lactose