title: Induction of immunological memory in mice by RNA extract.
abstract: RNA extract isolated from spleens of mice immunized with lipopolysaccharide from E. coli induced an immunological memory in normal mice. Application of small amounts of corresponding antigen provoked a specific secondary immune response in RNA primed mice.
mesh_terms: D000818:Animals; D004926:Escherichia coli; D005260:Female; D006385:Hemagglutination Inhibition Tests; D007156:Immunologic Memory; D008070:Lipopolysaccharides / Q000276:immunology*; D051379:Mice; D012313:RNA / Q000276:immunology*; D013154:Spleen / Q000276:immunology*
chemical_list: D008070:Lipopolysaccharides; D012313:RNA