Mechanical ventilation of infants of less than 1,501 gm birth weight: Health, growth, and neurologic sequelae.
A two-year follow-up study of 73 low-birth-weight ( less than 1,501 gm) infants treated with positive pressure ventilation as neonates revealed the following: 24% incidence of lower respiratory tract infections during the first year; weight and height at two years averaging between tenth and twenty-fifth percentiles; major neurologic defects diagnosed in 14 boys (39%) and seven girls (18%) with one-year Bayley scores of less than 80. Major neurologic sequelae were closely associated with a neonatal history of seizures and intracranial hemorrhage and were more common in boys, survivors weighing more than 1,000 gm and following high-risk pregnancies.
D001049:Apnea / Q000628:therapy; D001724:Birth Weight; D001827:Body Height; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006128:Growth; D006429:Hemiplegia / Q000209:etiology; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D007223:Infant; D007231:Infant, Newborn; D007384:Intermittent Positive-Pressure Breathing / Q000009:adverse effects*; D008297:Male; D009128:Muscle Spasticity / Q000209:etiology; D011175:Positive-Pressure Respiration / Q000009:adverse effects*; D011782:Quadriplegia / Q000209:etiology; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*; D012141:Respiratory Tract Infections / Q000209:etiology; D012178:Retinopathy of Prematurity / Q000209:etiology; D012640:Seizures / Q000209:etiology