title: Patient acceptability of two diuretic/potassium supplement preparations.
abstract: In a random crossover study in general practice, sixty patients with heart failure were given one week's maintenance treatment with the recommended dosage of Burinex K or Lasix+K. Burinex K appeared to be easier to swallow than the supplement tablets of Lasix+K although the differences were not significant. Patients showed a highly significant preference to take two tablets on one occasion (Burinex K) rather than two different types of tablet on three separate occasions (Lasix+K). Despite pharmacological arguments in favour of stimultaneous versus separate administration of potassium supplement and diuretic, patient acceptibility is of over-riding importance in the long-term.
mesh_terms: D000368:Aged; D002034:Bumetanide / Q000008:administration & dosage* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003679:Deglutition; D003692:Delayed-Action Preparations; D004232:Diuretics / Q000008:administration & dosage*; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D005260:Female; D005665:Furosemide / Q000008:administration & dosage* / Q000627:therapeutic use; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D011188:Potassium / Q000008:administration & dosage* / Q000627:therapeutic use; D011795:Surveys and Questionnaires; D013607:Tablets
chemical_list: D003692:Delayed-Action Preparations; D004232:Diuretics; D004338:Drug Combinations; D013607:Tablets; D002034:Bumetanide; D005665:Furosemide; D011188:Potassium