The increasing isolation of Serratia species from clinical specimens.
A 14-month survey was undertaken in a diagnostic bacteriology laboratory to determine the incidence of Serratia spp. in routine clinical specimens. Gram-negative organisms with enterobacteria-like colonies were tested by a simple screening procedure. Fifty-eight strains of S. marcescens and two strains of S. liquefaciens were isolated from 59 patients. The strains were usually non-pigmented and exhibited multiple antibiotic resistance. Serotyping and determination of bacteriocine sensitivity patterns revealed that the majority of infections were sporadic, although episodes of cross-infection did occur. S. marcescens was considered to contribute significantly to morbidity and mortality in 53% of patients and appears to be of increasing importance in hospital-acquired infections.
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001430:Bacteriocins / Q000032:analysis; D003428:Cross Infection / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D004756:Enterobacteriaceae Infections / Q000382:microbiology*; D006801:Humans; D008875:Middle Aged; D012703:Serotyping; D012705:Serratia / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification*
D000900:Anti-Bacterial Agents; D001430:Bacteriocins