Endotoxin protein: a B-cell mitogen and polyclonal activator of C3H/HeJ lymphocytes.
A cell wall protein that is ordinarily complexed to the lipopolysaccharide endotoxin in gram-negative bacteria has been separated by the use of aqueous phenol. The protein is active as a B-cell mitogen and polyclonal activator of murine lymphocytes including the C3H/HeJ strain which is a nonresponder to lipoplysaccharide or lipid A.
D000818:Animals; D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology*; D001426:Bacterial Proteins / Q000276:immunology*; D002999:Clone Cells / Q000276:immunology; D004731:Endotoxins; D004926:Escherichia coli / Q000276:immunology; D008070:Lipopolysaccharides / Q000276:immunology; D008213:Lymphocyte Activation; D051379:Mice; D008809:Mice, Inbred C3H; D008934:Mitogens; D011135:Polysaccharides, Bacterial / Q000276:immunology; D012485:Salmonella typhi / Q000276:immunology; D013329:Structure-Activity Relationship
D001426:Bacterial Proteins; D004731:Endotoxins; D008070:Lipopolysaccharides; D008934:Mitogens; D011135:Polysaccharides, Bacterial