Neutrophil function in lymphoreticular malignancy.
Neutrophil function has been assessed in 62 patients with lymphoreticular malignancy by means of the NBT test and an in vitro micro-organism killing technique. Normal or enhanced phagocytosis was found, the greatest enhancement being found in patients with disseminated disease (in the absence of infections). Candicidal capacity alone was depressed in 7 patients but 4 of these showed depressed cell-mediated immunity to Candida antigen. Splenectomy, radiotherapy and chemotherapy did not alter phagocytic function.
D000946:Antigens, Fungal; D002176:Candida albicans / Q000276:immunology; D002470:Cell Survival; D006689:Hodgkin Disease / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007958:Leukocyte Count; D008223:Lymphoma / Q000276:immunology*; D009504:Neutrophils / Q000276:immunology*; D009580:Nitroblue Tetrazolium; D010587:Phagocytosis
D000946:Antigens, Fungal; D009580:Nitroblue Tetrazolium