Specific cell-mediated immunity in the laboratory diagnosis of dermatophytic infections.
The leukocyte adherence inhibition test was used to detect cell-mediated immunity against antigens of the infecting fungi in patients with dermatophytosis. The species-specific diagnosis thus obtained was in all cases consistent with the eventual results of mycological examination. Most of the patients also produced a specific circulating blocking factor, the detection of which may be a useful guide to the success of treatment. Immunological reactivity against Candida albicans was also observed.
D000328:Adult; D000368:Aged; D000946:Antigens, Fungal; D003881:Dermatomycoses / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D006801:Humans; D007104:Immune Adherence Reaction; D007111:Immunity, Cellular; D007158:Immunologic Techniques; D007962:Leukocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D013045:Species Specificity
D000946:Antigens, Fungal