Comparison of salmefamol with salbutamol aerosols in asthamatics.
In twelve asthmatic patients 200 mug of salmefamol and salbutamol given by metered aerosol produced a similar initial effect on FEV1, FVC and PEFR without significant effect on heart rate or blood pressure. The duration of effect of salbutamol was approximately 4 hours; there was still an appreciable effect from salmefamol at 8 hours.
D000328:Adult; D000336:Aerosols; D000368:Aged; D000420:Albuterol / Q000494:pharmacology*; D001249:Asthma / Q000503:physiopathology*; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D005260:Female; D005541:Forced Expiratory Volume; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D010366:Peak Expiratory Flow Rate; D013997:Time Factors; D014797:Vital Capacity
D000336:Aerosols; D007545:Isoproterenol; D000420:Albuterol