title: Malignant atrophic papulosis of Degos. Report of a patient who failed to respond to fibrinolytic therapy.
abstract: A 21-year-old woman with eventually fatal malignant atrophic papulosis (Degos disease) was treated primarily with the fibrinolytic agents phenformin hydrochloride and ethylestrenol. In spite of therapy, primarily central nervous system manifestations led to the patient's death.
mesh_terms: D000328:Adult; D005032:Ethylestrenol / Q000627:therapeutic use*; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010629:Phenformin / Q000627:therapeutic use*; D012867:Skin / Q000098:blood supply; D012871:Skin Diseases / Q000188:drug therapy* / Q000401:mortality; D013577:Syndrome; D013927:Thrombosis / Q000188:drug therapy
chemical_list: D005343:Fibrinolytic Agents; D005032:Ethylestrenol; D010629:Phenformin