Localization of low molecular weight acrosin-trypsin inhibitors in the boar genital tract by immunofluorescence.
Using the indirect immunofluorescent technique, the occurrence and distribution of the low molecular weight acid-stable acrosin inhibitors from boar seminal plasma (BSAI) in the boar genital tract was studied applying specific inhibitor-directed rabbit-immunoglobulins. The acrosin inhibitors are localized in the mucosa cells of the cauda epididymis, the vas deferens, the seminal vesicles, the urethra  and distinct glandular units of the prostate. The wide distribution of the acrosin inhibitors within the boar genital tract indicates a protective function towards the destructive proteolytic potential of acrosin liberated e.g. during sperm aging from desintegrating spermatozoa.
D000176:Acrosin / Q000037:antagonists & inhibitors* / Q000276:immunology; D000818:Animals; D004822:Epididymis / Q000276:immunology; D004847:Epithelial Cells; D004848:Epithelium / Q000276:immunology; D005455:Fluorescent Antibody Technique; D005837:Genitalia, Male / Q000378:metabolism*; D008297:Male; D008970:Molecular Weight; D011467:Prostate / Q000276:immunology; D011480:Protease Inhibitors; D012669:Seminal Vesicles / Q000276:immunology; D013552:Swine; D013737:Testis / Q000378:metabolism; D014361:Trypsin Inhibitors / Q000276:immunology*; D014521:Urethra / Q000276:immunology; D014649:Vas Deferens / Q000276:immunology
D011480:Protease Inhibitors; D014361:Trypsin Inhibitors; D000176:Acrosin