title: Dietary fiber--in historical perspective.
abstract: Epidemiologic reports have linked how intakes of dietary fiber with numerous diseases and abnormal conditions. They range from diverticulitis to coronary thrombosis, from simple constipation to possible carcinoma of the colon. The supposed etiology underlying these and other conditions is discussed in terms of the properties of cellulose, lignin, and hemicelluloses, including pectin, which collectively make up dietary fiber. Other major organic components of plant foods, apart from fiber, protein, fat, sugars and starches, are considered briefly. The desirability of improved nomenclature is emphasized. Urgently needed is a thorough study of the biochemistry and metabolism, using experimental animals, of dietary fiber in foods. Only when this is done can there be a good understanding of the mechanisms involved and a realization of the possibilities suggested by the epidemiologic studies.
mesh_terms: D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology; D002400:Cathartics; D002482:Cellulose / Q000494:pharmacology; D003106:Colon / Q000502:physiology; D003108:Colonic Diseases / Q000209:etiology; D003731:Dental Caries / Q000209:etiology; D003920:Diabetes Mellitus / Q000209:etiology; D004043:Dietary Fiber / Q000378:metabolism / Q000494:pharmacology; D004063:Digestion; D005504:Food Analysis; D005767:Gastrointestinal Diseases / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D008031:Lignin; D008297:Male; D009765:Obesity / Q000209:etiology; D010368:Pectins; D011134:Polysaccharides; D009626:Terminology as Topic
chemical_list: D002400:Cathartics; D004043:Dietary Fiber; D011134:Polysaccharides; D010368:Pectins; D002482:Cellulose; D008031:Lignin