title: The use of controlled clinical trials in gastric surgery.
abstract: Evaluation of results of different surgical treatment of duodenal ulcer requires controlled clinical trials. Some of the published trials have flaws in conception and realization: heterogeneity of material, absence of randomization, incomplete follow-up and incomplete data in results. The author presents a controlled clinical trial, following a carefully planned protocol, comparing results of gastric proximal vagotomy without drainage to those of selective vagotomy with gastro-jejunostromy. This study has shown the mean term advantages of proximal gastric vagotomy without drainage, and of the controlled clinical trial in demonstrating the pros-and-cons of a gastric operation for a duodenal ulcer.
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D004322:Drainage; D004381:Duodenal Ulcer / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D014628:Vagotomy