Probucol, a new cholesterol lowering drug.
The purpose of this investigation was to determine the ability of Dh-581 (Procubol) (See Figure 1) to reduce the level of serum cholesterol for extended periods of time and to maintain the reduction without loss of effectiveness. The effects of DH-581 on triglycerides and the safety and tolerance of daily doses were also assessed.
D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D002784:Cholesterol / Q000097:blood; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010636:Phenols / Q000627:therapeutic use*; D011341:Probucol / Q000627:therapeutic use*; D014280:Triglycerides / Q000097:blood
D000924:Anticholesteremic Agents; D010636:Phenols; D014280:Triglycerides; D002784:Cholesterol; D011341:Probucol