title: Giant cell synovitis associated with failed polyethylene patellar replacements.
abstract: Destroyed patellar articular surfaces were replaced with a high molecular weight polyethylene prosthesis in two patients. The patellofemoral articulation of the femur consisted of eburnated bone in one case and degenerative cartilage in the other. Both operations failed within one year because of a giant cell synovitis caused by a high volume (0.2 cc) of fine polyethylene (1-100 mu) wear particles. Ultra high molecular weight polyethylene should not be used as a prosthetic bearing surface to articulate against cortical, cancellous or eburnated bone or against degenerative articular cartilage in a major joint.
mesh_terms: D000368:Aged; D005260:Female; D005549:Foreign-Body Reaction / Q000139:chemically induced* / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010329:Patella / Q000601:surgery; D011095:Polyethylenes / Q000009:adverse effects*; D019736:Prostheses and Implants / Q000009:adverse effects; D013583:Synovial Membrane / Q000473:pathology; D013585:Synovitis / Q000139:chemically induced* / Q000209:etiology / Q000473:pathology
chemical_list: D011095:Polyethylenes