Hypothalamo-pituitary-adrenal function in Parkinsonian patients treated with melatonin.
The pineal principle, melatonin, was administered to 4 Parkinsonian patients. Hypothalam0-pituitary-adrenal function tests were performed before and after 4 weeks of treatment. At a maximum dosage of 1 g daily no impairment of H-P-A function was detected.
D000311:Adrenal Glands / Q000503:physiopathology*; D002940:Circadian Rhythm; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007031:Hypothalamus / Q000503:physiopathology*; D008297:Male; D008550:Melatonin / Q000378:metabolism / Q000627:therapeutic use*; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D010902:Pituitary Gland / Q000503:physiopathology*; D013256:Steroids / Q000652:urine
D013256:Steroids; D008550:Melatonin; D006854:Hydrocortisone