Transferable and non-transferable drug resistance in enteric bacteria from hospital and from general practice.
Drug resistance to 8 different antibiotics in Enterobacteriaceae isolated from different hospitals and two groups of general practitioners was studied. Escherichia coli dominated among the 632 strains investigated. Drug resistance was found in 62% of the 512 hospital strains and in 38% of the 120 strains from general practice. Multiple resistance was common especially in strains from hospital. R factors was found in 23% of the 317 drug-resistant strains from hospital and in 11% of the 46 drug-resistant strains from general practice. Resistance to streptomycin, sulphonamide and tetracycline either alone or in combinations were the most common traits transferred.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002701:Chloramphenicol / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects; D005194:Family Practice; D006761:Hospitals; D006801:Humans; D007612:Kanamycin / Q000494:pharmacology; D007709:Klebsiella / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009268:Nalidixic Acid / Q000494:pharmacology; D009582:Nitrofurantoin / Q000494:pharmacology; D011511:Proteus / Q000187:drug effects; D011815:R Factors / Q000187:drug effects; D013307:Streptomycin / Q000494:pharmacology; D013449:Sulfonamides / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D013449:Sulfonamides; D009268:Nalidixic Acid; D007612:Kanamycin; D002701:Chloramphenicol; D009582:Nitrofurantoin; D013752:Tetracycline; D013307:Streptomycin