Clinical evaluation of keto profen (Orudis) in rheumatoid arthritis: results of a multi-centre double-blind trial against phenylbutazone.
In a double-blind cross-over trial in rheumatoid arthritis, no difference was found between ketoprofen and phenylbutazone with regard to clinical efficacy at the dosages used. There was a higher incidence of side-effects reported during treatment with phenylbutazone.
D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D001577:Benzophenones / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007660:Ketoprofen / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010653:Phenylbutazone / Q000009:adverse effects / Q000627:therapeutic use*
D000893:Anti-Inflammatory Agents; D001577:Benzophenones; D007660:Ketoprofen; D010653:Phenylbutazone