title: Leucocyte aggregation and lymphocyte transformation induced by mercuric chloride.
abstract: Leuco-aggregation tests carried out on normal subjects using the non-specific mitogen mercuric chloride produced micro-aggregates in the concentration range 2-100 mug/ml with a peaking effect at about 10 mug/ml. These results showed good correlation with lymphocyte transformation test thymidine uptake ratios which were maximal at 2-10 mug/ml.
mesh_terms: D004306:Dose-Response Relationship, Immunologic; D006801:Humans; D007111:Immunity, Cellular; D007158:Immunologic Techniques; D066298:In Vitro Techniques; D007962:Leukocytes / Q000187:drug effects / Q000276:immunology*; D008213:Lymphocyte Activation; D008628:Mercury / Q000494:pharmacology*; D008934:Mitogens
chemical_list: D008934:Mitogens; D008628:Mercury