title: Cutaneous alternariosis.
abstract: Two patients with cutaneous alternaria infection are presented. In both patients the skin lesions were characterized by multiple non-healing ulcers covered with dry crusts. Although the skin changes were macroscopically alike in the two patients, differences in the histology were seen. Both patients had primary debilitating diseases. A review of the literature is presented and revealed an additional ten cases of cutaneous alternariosis. Methods for the isolation of Alternaria and the susceptibility of the fungus to antimycotic drugs are presented.
mesh_terms: D000293:Adolescent; D000328:Adult; D000528:Alternaria / Q000187:drug effects / Q000302:isolation & purification; D000666:Amphotericin B / Q000494:pharmacology; D002675:Child, Preschool; D002750:Chlorquinaldol / Q000627:therapeutic use; D003881:Dermatomycoses / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005437:Flucytosine / Q000494:pharmacology; D005840:Gentian Violet / Q000627:therapeutic use; D006118:Griseofulvin / Q000494:pharmacology; D006801:Humans; D008297:Male; D008875:Middle Aged; D003904:Mitosporic Fungi; D009761:Nystatin / Q000494:pharmacology / Q000627:therapeutic use; D011196:Potassium Permanganate / Q000627:therapeutic use; D012883:Skin Ulcer / Q000188:drug therapy / Q000382:microbiology
chemical_list: D011196:Potassium Permanganate; D009761:Nystatin; D006118:Griseofulvin; D000666:Amphotericin B; D002750:Chlorquinaldol; D005437:Flucytosine; D005840:Gentian Violet