Ciclopirox: a new topical pyrodonium antimycotic agent. A double-blind study in superficial dermatomycoses.
One percent Ciclopirox solution, a new topical antimycotic agent, was used in a double-blind controlled trial in 105 dermatomycosis patients. Twelve of the patients were lost to follow-up. Of the remaining ninety-three patients, forty-four were treated with the active drug, forty-nine with a placebo. The cure rate amongst those using ciclopirox was significantly superior to that of the placebo. The drug was effective against Trichophyton rubrum, T. violaceum, T. mentagrophytes and Malassezia furfur.
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D010919:Placebos; D011728:Pyridones / Q000627:therapeutic use*; D014005:Tinea / Q000188:drug therapy*
D000935:Antifungal Agents; D010919:Placebos; D011728:Pyridones