title: [Double blind crossover study of pseudoephedrine and triprolidine alone and in combination in the treatment of allergic rhinitis (author's transl)].
abstract: In a double-blind crossover trial of pseudoephedrine 60 mg. and triprolidine 2.5 mg. alone and in combination, on 40 volunteers suffering from allergic rhinitis, both drugs were found superior to placebo in reducing the effects of allergic rhinitis and were of equal efficacy. The combination tablet was consistently better than either drug in several of the assessments and was the treatment which the subjects, as a whole, preferred. Side effects were not a problem with any of the medications.
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004809:Ephedrine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos; D011725:Pyridines / Q000627:therapeutic use*; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy*; D013607:Tablets; D014311:Triprolidine / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D010919:Placebos; D011725:Pyridines; D013607:Tablets; D014311:Triprolidine; D004809:Ephedrine
vernacular_title: Estudio doble ciego cruzado de seudoefedrina y triprolidina solas y en combinación, en el tratamiento de la rinitis alérgica