Functional differentiation of the FSH-synthesizing cells in the pars distalis of the fetal pituitary gland of the rat.
The onset of FSH synthesis in the embryonic pituitary gland of the rat was studied by a peroxidase-labelled antibody method. The first FSH-containing cells appeared on the 20th day of embryonic life. From that day onwards, FSH cells increased rapidly in number. It was found that in adult animals some pituitary cells reacted with both anti-HCG and anti-FSH sera, indicating the simultaneous presence of LH and FSH in the same cell.
D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism; D002454:Cell Differentiation; D005260:Female; D005640:Follicle Stimulating Hormone / Q000096:biosynthesis*; D005865:Gestational Age; D007124:Immunoenzyme Techniques; D007986:Luteinizing Hormone / Q000096:biosynthesis; D008297:Male; D010902:Pituitary Gland / Q000166:cytology / Q000196:embryology* / Q000378:metabolism; D051381:Rats
D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone