Plasma renin concentration and the hypotensive effect of bendrofluazide and of atenolol.
1. The anti-hypertensive effect of atenolol was greater than that of bendrofluazide. 2. The change in systolic blood pressure caused by bendrofluazide showed a significant inverse correlation iwth the plasma renin concentration (r=-0-47; P less than 0-01). 3. The correlation between the change in systolic blood pressure caused by atenolol and the plasma renin concentration was not significant (r =0-28; 0-1 greater than P greater than 0-05). 4. Plasma renin concentration was unaffected by atenolol.
D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001262:Atenolol / Q000627:therapeutic use*; D001539:Bendroflumethiazide / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D011412:Propanolamines / Q000627:therapeutic use*; D012083:Renin / Q000097:blood*
D000959:Antihypertensive Agents; D011412:Propanolamines; D001262:Atenolol; D001539:Bendroflumethiazide; D012083:Renin