title: Development of immunoglobulin-containing cell populations in intestine, spleen, and mesenteric lymph node of the young pig, as demonstrated by peroxidase-conjugated antiserums.
abstract: Peroxidase-conjugated antibody to porcine immunoglobulins A, G, and M were used in a light microscope study of the development of immunoglobulin-containing cells in small intestine, spleen, and mesenteric lymph node of the young pig. Many cells staining for each of the 3 immunoglobulin classes were present in duodenum of 1-week-old-pigs, and the number increased in succeeding weeks. Immunoglobulin M cells outnumbered immunoglobulin A cells in the 1- to 3-week-old pigs, after which immunoglobulin A cells predominated. Immunoglobulin G cells were present in considerable but smaller numbers at all ages. Stained cells in spleen and mesenteric lymph node were not detected until after pigs were 1 week old.
mesh_terms: D000367:Age Factors; D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology*; D004386:Duodenum / Q000276:immunology; D007082:Ileum / Q000276:immunology; D007124:Immunoenzyme Techniques; D007070:Immunoglobulin A / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007421:Intestine, Small / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology*; D013154:Spleen / Q000276:immunology*; D013552:Swine / Q000276:immunology*
chemical_list: D007070:Immunoglobulin A; D007075:Immunoglobulin M