Accelerated detection of lymphocytic choriomeningitis virus in diagnostic specimens.
Lymphocytic choriomeningitis virus could be demonstrated earlier in mice inoculated with clinical specimens if the mice were sacrificed before they appeared sick for examination by the fluorescent antibody technique. In the procedure, the optimal route for inoculation was intracerebral and the best organ tested for staining was the brain.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001921:Brain / Q000276:immunology; D003937:Diagnosis, Differential; D005069:Evaluation Studies as Topic; D005455:Fluorescent Antibody Technique; D007668:Kidney / Q000276:immunology; D008099:Liver / Q000276:immunology; D008216:Lymphocytic Choriomeningitis / Q000175:diagnosis*; D008217:Lymphocytic choriomeningitis virus / Q000276:immunology / Q000302:isolation & purification*; D051379:Mice; D013045:Species Specificity; D013154:Spleen / Q000276:immunology
D000956:Antigens, Viral