The effect of folic acid on gingival health.
On days 0 and 30 of a double blind study, two groups of 15 subjects each were evaluated using a plaque index, a gingival index, a gingival exudate flow and fasting plasma folic acid levels. Group I received 2 mg of folic acid twice daily for 30 days while Group II received a placebo. Results of the study seem to indicate that folic acid supplemented to the diet may increase the resistance of the gingiva to local irritants and thus lead to a reduction in inflammation.
D000328:Adult; D005492:Folic Acid / Q000494:pharmacology*; D005881:Gingiva / Q000187:drug effects*; D005883:Gingival Crevicular Fluid / Q000187:drug effects; D005891:Gingivitis / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D010919:Placebos
D010919:Placebos; D005492:Folic Acid