title: Persistence of Treponema pallidum following penicillin G therapy. Report of two cases.
abstract: The isolation of Treponema pallidum from cerebrospinal fluid (CSF) obtained from two adult patients, both of whom had normal CSF values except for positive fluorescent treponemal antibody-absorption (FTA-ABS) tests and both of whom had received currently recommended courses of penicillin, raises important considerations in the treatment of neurosyphilis in adults.
mesh_terms: D000907:Antibodies, Bacterial / Q000134:cerebrospinal fluid; D002555:Cerebrospinal Fluid / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009494:Neurosyphilis / Q000188:drug therapy; D010401:Penicillin G Benzathine / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D010403:Penicillin Resistance; D011935:Reagins / Q000134:cerebrospinal fluid; D014210:Treponema pallidum / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000907:Antibodies, Bacterial; D011935:Reagins; D010401:Penicillin G Benzathine