Long survival after renal transplantation in man.
The indications for transplantation, complications, management and results in 127 consecutive patients who had received renal transplants between October 1960 and December 1974 are presented. In 2 cases the donor was an identical twin, in 22 a living relative other than a twin, in 2 an unrelated individual in whom nephrectomy was performed for therapeutic reasons and in 101 a cadaver. At the end of the period under review there were 37 patients alive with grafts which had functioned for 6 months or more; of these, 28 had survived for more than 2 years, 13 for more than 5 years, 6 for more than 8 years and 2 for more than 12 years. Thirty-four patients were employed or doing routine housework or receiving full-time education. One patient fathered a child 4 years after transplantation; another gave birth to a healthy infant 3 years after transplantation.
D000293:Adolescent; D000328:Adult; D000961:Antilymphocyte Serum / Q000627:therapeutic use; D002102:Cadaver; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection; D006680:HLA Antigens; D006650:Histocompatibility Testing; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007165:Immunosuppression Therapy; D007239:Infections / Q000209:etiology; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000209:etiology; D011183:Postoperative Complications; D011241:Prednisone / Q000627:therapeutic use; D014019:Tissue Donors; D014184:Transplantation, Homologous; D014652:Vascular Diseases / Q000209:etiology
D000961:Antilymphocyte Serum; D006680:HLA Antigens; D011241:Prednisone