title: [The efficacy of Piracetam on the mental functional capacity of chronic alcoholics (author's transl)].
abstract: Piracetam, 1-pyrrolidone acetamid, was tested in 40 chronic alcoholics with a more or less marked psycho-organic syndrome by means of psychological tests. It was a double-blind-cross-over study. Statistical analysis of the results showed that Piracetam improves the energo-functional capacity of the cortex i.e. the basal functions of the cortical cells such as activating capacity, vital dynamic, flexibility, intellectual reactivity and stress tolerance. Apart from the overall improvement we also observed an improvement of specific cerebral performances which is however unimportant in comparison with the greneralized effect.
mesh_terms: D000437:Alcoholism / Q000150:complications / Q000534:rehabilitation*; D001519:Behavior / Q000187:drug effects; D001925:Brain Damage, Chronic / Q000188:drug therapy* / Q000209:etiology; D002525:Cerebellar Cortex / Q000187:drug effects; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D010889:Piracetam / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D010919:Placebos; D011581:Psychological Tests; D011604:Psychoses, Alcoholic / Q000188:drug therapy; D011760:Pyrrolidinones / Q000627:therapeutic use*
chemical_list: D010919:Placebos; D011760:Pyrrolidinones; D010889:Piracetam
vernacular_title: Die Wirkung von Piracetam auf das geistige Leistungsverhalten chronischer Alkoholiker