Anomalies in the selection of mutants of Schizosaccharomyces pombe resistant to 8-azaguanine.
Anomalies in selection render 8-azaguanine unsuitable as a selective agent for screening forward mutations in continuour cultures of Sch. pombe. This system may, however, provide tha basis for an enrichment method for the simultaneous isolation of mutants at two loci.
D001203:Ascomycota / Q000187:drug effects*; D001375:Azaguanine / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D005821:Genetic Techniques; D009154:Mutation; D012568:Schizosaccharomyces / Q000187:drug effects*; D012641:Selection, Genetic
D001375:Azaguanine