title: [Comparative tests of tetracian and of the new local anesthetic carticain in spinal anesthesiasa double placebo study].
abstract: Onset of effect, degree of effect and duration of effect of Tetracain (Pantocain) and Carticain (Ultracain) in hyperbaric solutions were compared on 60 subjects with spinal anesthesias. In the double-blind trial with individual randomization, no difference was found regarding the onset of action (latency period), the intensity of analgesia and the extent of the muscle blocking. With 151 +/- 48.9 min., the duration of analgesia with Carticain was distinctly and significantly shorter than in the case of Tetracain with 278 +/- 108.9 min., but thoroughly sufficient for the nature and duration of the surgical operations on pour patients, even in the postoperative phase.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000775:Anesthesia, Spinal; D000779:Anesthetics, Local / Q000592:standards*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011292:Premedication; D013748:Tetracaine / Q000592:standards*
chemical_list: D000779:Anesthetics, Local; D013748:Tetracaine
vernacular_title: Vergleichende Untersuchungen von Tetracain und dem neuen Lokalanästhetikum Carticain bei Spinalanästhesien-eine Doppelblindstudie