title: Studies on the energetic metabolism of Shigella flexneri x Escherichia coli hybrids devoid of penetration ability. IV. Growth characteristics in the presence of some tricarboxylic acid cycle intermediates.
abstract: The dynamics of avirulant lac+KCP- hybrids Sh. flexneri multiplication was investigated in minimal medium in the presence of some tricarboxylic acid cycle intermediates (fumarate, succinate, malate) and pyruvate. It was established that in spite of the loss of virulence in the rate of the multiplication of the hybrid strains, in comparison with that of the virulent recipient strains of Sh. flexneri, considerable differences were not observed.
mesh_terms: D002455:Cell Division; D002952:Citric Acid Cycle; D004926:Escherichia coli / Q000254:growth & development / Q000378:metabolism*; D005796:Genes; D006824:Hybridization, Genetic; D007637:Keratoconjunctivitis / Q000382:microbiology; D007785:Lactose; D012763:Shigella flexneri / Q000254:growth & development / Q000378:metabolism* / Q000472:pathogenicity
chemical_list: D007785:Lactose