A within-patient comparison of bethanidine, methyldopa and propranolol in the treatment of hypertension.
1. A within-patient comparison showed that bethanidine, methyldopa and propranolol produced similar control of the blood pressure. 2. Unlike bethanidine, propranolol did not produce postural and exercise hypotension; methyldopa was intermediate in effect. 3. Overall side effects were of a similar incidence though there were differences in incidence of particular side effects.
D001627:Bethanidine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004232:Diuretics / Q000627:therapeutic use; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008750:Methyldopa / Q000627:therapeutic use*; D005082:Physical Exertion; D011187:Posture; D011433:Propranolol / Q000627:therapeutic use*; D012119:Respiration / Q000187:drug effects
D004232:Diuretics; D006146:Guanidines; D008750:Methyldopa; D011433:Propranolol; D001627:Bethanidine