title: In vitro and in vivo transfer of drug resistance for Salmonella and Escherichia coli strains in turkeys.
abstract: In vitro and in vivo transfers of antibiotic drug resistance were observed when isolates of multi-resistant Salmonella saint-paul and Escherichia coli donors were mated with multi-sensitive E coli and Salmonella typhimurium recipients, respectively. For in vivo studies, day-old turkey poults were used. Drug resistances were transferred either alone or in various combinations. In vitro, transfer was more frequent from E coli to S typhimurium; in vivo, transfer was more often observed from S saint-paul to E coli. Transfer occurred in vivo within 3 or 6 days after the recipient strain was given to poults previously infected with donor bacteria. In some instances, phage typing of S typhimurium indicated a change after transfer of drug resistance from E coli to S typhimurium. The criteria for in vivo transfer of drug resistance were discussed, and the implications of a change in phage type were noted.
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development; D005111:Extrachromosomal Inheritance; D011815:R Factors; D012475:Salmonella / Q000187:drug effects* / Q000254:growth & development; D012486:Salmonella typhimurium / Q000187:drug effects / Q000254:growth & development; D014422:Turkeys / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents