A double-blind crossover comparison of Orudis (ketoprofen) and indomethacin in the treatment of rheumatoid arthritis.
Twenty-three patients with rheumatoid arthritis participated in a double-blind crossover investigation of ketoprofen (Orudis) and indomethacin. Ratings which assessed the degree of joint involvement showed consistently greater improvement with Orudis, and side-effects occurred with less frequency. The majority of patients expressed a definite preference for Orudis.
D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D001577:Benzophenones / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects / Q000627:therapeutic use*; D007660:Ketoprofen / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
D001577:Benzophenones; D007660:Ketoprofen; D007213:Indomethacin