[Cytological classification of adult acute leukemia (author's transl)].
134 cases of acute leukemia in adults were classified according a "double blind" cytological diagnosis, a cytochemical study, and lysozyme assay. Each type has distinct characters, allowing a good nosological definition. The histochemical methods, as well as lysozyme assay are usually unnecessary, particularly in well differenciated myeloblastic, promyelocytic or myelo-monocytic acute leukemia. They are, on the contrary, frequently useful in poorly differenciated myeloblastic or monoblastic leukemia. But, they cannot help to solve every problem in cytological diagnosis: there are still 10% of undifferenciated acute leukemia, the lymphoblastic acute leukemia are not clearly defined and 4% of cases of acute leukemia have atypical characters leading to difficulties in cytological classification. The need for new methods and markers is emphasized.
D000208:Acute Disease; D000328:Adult; D001773:Blood Cells / Q000648:ultrastructure; D001853:Bone Marrow / Q000648:ultrastructure; D001854:Bone Marrow Cells; D003937:Diagnosis, Differential; D006651:Histocytochemistry; D006801:Humans; D007938:Leukemia / Q000097:blood / Q000175:diagnosis* / Q000378:metabolism; D009113:Muramidase / Q000097:blood / Q000652:urine
D009113:Muramidase
Classification cytologique des leucémies aiguës de l'adulte