title: [Antibacterial activity of the derivatives of cholic acid (author's transl)].
abstract: The synthesis of derivatives of cholic acid with L-lysine and Lysil-lysine with antibacterial activity, is here described. Derivatives with one molecule of lysine show antibacterial activity at 100 mug/ml concentration, while lysil-lysine derivatives, particularly Col-Lys-Lys-NH2-2HCl, are effective also at 25 mug/ml.
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D002793:Cholic Acids / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011514:Proteus vulgaris / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013297:Streptococcus pyogenes / Q000187:drug effects
chemical_list: D002793:Cholic Acids
vernacular_title: Attivita' antibatterica di alcuni derivati dell'acido colico