Salmonellosis in mice: immunization experiments with salmonella-escherichia coli hybrids.
Mice vaccinated with Escherichia coli hybrids experesing Salmonella O antigens were protected against lethal challenge doses of Salmonella strains. Counts of challenge bacteria in mouse organs revealed that a live hybrid vaccine was slightly more efficient than an acetone-killed vaccine.
D000818:Animals; D001428:Bacterial Vaccines / Q000627:therapeutic use*; D004926:Escherichia coli / Q000276:immunology*; D006822:Hybrid Cells; D007114:Immunization; D051379:Mice; D012480:Salmonella Infections / Q000276:immunology / Q000517:prevention & control*; D012486:Salmonella typhimurium / Q000276:immunology*
D001428:Bacterial Vaccines