title: Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis.
mesh_terms: D000745:Anemia, Hemolytic, Congenital / Q000378:metabolism*; D000818:Animals; D002248:Carbon Monoxide; D002908:Chronic Disease; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D005260:Female; D006418:Heme / Q000096:biosynthesis*; D006461:Hemolysis; D006579:Heterozygote; D006720:Homozygote; D011163:Hydroxymethylbilane Synthase / Q000378:metabolism; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology; D006899:Mixed Function Oxygenases / Q000096:biosynthesis*; D000623:Porphobilinogen Synthase / Q000378:metabolism; D014018:Tissue Distribution
chemical_list: D006418:Heme; D002248:Carbon Monoxide; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D011163:Hydroxymethylbilane Synthase; D000623:Porphobilinogen Synthase