title: [Effect of intramuscular dihydroergotamine on blood circulation in the early postoperative phase. A clinical study].
abstract: The effects of Dihydergot (1,0 mg i.m.) and a placebo on orthostatic regulation disturbances were examined during the mobilisation in the first post-operative phase. According to a modified Schellong-test, 100 fresh-operated patients with hyper- rsp. hypodiastolic regulation disturbances were checked on the first post-operative day. In comparison with the placebo, Dihydergot showed a stabilisation of the systolic blood pressure and a decrease of the pulse rate during orthostatic conditions. Neither Dihydergot nor placebo influenced the diastolic blood pressure. Orthostatically caused side effects were observed less frequent within Dihydergot - therapy than under placebo.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects*; D002986:Clinical Trials as Topic; D004087:Dihydroergotamine / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D004879:Ergotamines; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007024:Hypotension, Orthostatic / Q000517:prevention & control*; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D010919:Placebos; D011183:Postoperative Complications / Q000517:prevention & control; D011187:Posture; D013514:Surgical Procedures, Operative
chemical_list: D004879:Ergotamines; D010919:Placebos; D004087:Dihydroergotamine
vernacular_title: Die Kreislaufbeeinflussung durch Dihydroergotamin intramuskulär in der frühen postoperativen Phase. Eine klinische Studie