The effects of continuous positive airway pressure on lung mechanics and lung volumes in the neonate.
We have studied the effect of continuous positive airways pressure (CPAP) on the lung mechanics and thoracic gas volumes on 15 occasions in 12 healthy neonates. As expected, the thoracic gas volume rose and total pulmonary resistance fell. The dynamic compliance fell on all occasions. 43% of the applied pressure was transmitted through to the mediastinal structures.
D000403:Airway Resistance; D004947:Esophagus / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D008170:Lung Compliance; D008176:Lung Volume Measurements / Q000295:instrumentation; D011175:Positive-Pressure Respiration; D011312:Pressure; D012119:Respiration; D013990:Tidal Volume