Chemotactic factor-induced release of membrane calcium in rabbit neutrophils.
The interaction of chemotactic factors (fMet-Leu-Phe and C5a) with rabbit neutrophils leads to rapid and specific release of membrane calcium, as evidenced by changes in the fluorescence of cell-associated chlorotetracycline. These two structurally different stimuli appear to interact with the same pool of membrane calcium.
D000818:Animals; D001693:Biological Transport, Active; D002118:Calcium / Q000097:blood*; D002634:Chemotaxis, Leukocyte; D002751:Chlortetracycline; D003182:Complement C5 / Q000494:pharmacology*; D005453:Fluorescence; D008715:Methionine / Q000031:analogs & derivatives*; D009239:N-Formylmethionine / Q000031:analogs & derivatives* / Q000494:pharmacology; D009504:Neutrophils / Q000378:metabolism*; D009842:Oligopeptides / Q000494:pharmacology*; D011817:Rabbits; D011955:Receptors, Drug / Q000187:drug effects
D003182:Complement C5; D009842:Oligopeptides; D011955:Receptors, Drug; D009239:N-Formylmethionine; D008715:Methionine; D002118:Calcium; D002751:Chlortetracycline