Simplified serological test for antibodies to Chlamydia trachomatis.
Three-hundred sixty sera from unselected patients attending two London venereal disease clinics were examined by a microimmunofluorescence test. Eleven egg-grown serotypes of Chlamydia trachomatis and the so-called "fast" strain SA2(f) were used as antigens. Of the 360 sera tested, 119 (33%) reacted to a titer of 1:16 or above with at least one antigen. Of these positive sera, over 50% cross-reacted with all 12 serotypes, and 95.5% reacted with SA2(f) in addition to other antigenic types. It is suggested that SA2(f) could be used as a single antigen for preliminary screening of a large number of sera for the presence or absence of chlamydial antibody.
D000907:Antibodies, Bacterial / Q000032:analysis*; D002692:Chlamydia trachomatis / Q000276:immunology*; D003429:Cross Reactions; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D012703:Serotyping
D000907:Antibodies, Bacterial