Normal human tissues contain RNA and antigens related to infectious adenovirus type 2.
Normal human tissues have been found to contain RNA which hybridises with four regions of the adenovirus type 2 genome, including one which contains the transforming gene(s) of this virus. The RNAs have also been extracted from gorilla organs, but not from those of chickens, suggesting that they are a feature of all normal higher primate tissues. Serological test suggest that these homologous RNAs are translated into proteins connected with essentially normal and virus-infected cell functions.
D000260:Adenoviruses, Human / Q000235:genetics* / Q000276:immunology; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D003429:Cross Reactions; D005260:Female; D005814:Genes, Viral; D006071:Gorilla gorilla / Q000382:microbiology; D006801:Humans; D008099:Liver / Q000382:microbiology; D009693:Nucleic Acid Hybridization; D010920:Placenta / Q000382:microbiology*; D011247:Pregnancy; D012367:RNA, Viral / Q000032:analysis*; D014018:Tissue Distribution; D014764:Viral Proteins / Q000276:immunology
D000956:Antigens, Viral; D012367:RNA, Viral; D014764:Viral Proteins