Preliminary studies of artificial immunization of rats against Plasmodium berghei and adoptive transfer of this immunity by splenic T and T + B cells.
Protective T lymphocyte and T+B lymphocyte responses in rats artificially immunized against P. berghei have been demonstrated by adoptive transfer. The techniques used could be developed for detailed analysis of protective lymphocyte responses generated by various methods of immunization, and their relationship to immunity.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D003037:Cobalt Radioisotopes; D004912:Erythrocytes / Q000469:parasitology / Q000528:radiation effects; D007114:Immunization / Q000379:methods*; D007116:Immunization, Passive / Q000379:methods*; D008288:Malaria / Q000517:prevention & control*; D008297:Male; D010962:Plasmodium berghei / Q000276:immunology* / Q000528:radiation effects; D051381:Rats; D013601:T-Lymphocytes / Q000276:immunology*
D003037:Cobalt Radioisotopes