title: Antibody-coated bacteria in the urine of preschool and school-aged girls with asymptomatic bacteriuria.
abstract: Urine samples from 3564 girls aged 2 to 13 years were screened for evidence of infection. Cultures were positive (bacteria count, more than 10(5)/ml) in 61 (1.7%) by the dipslide method and in 55 (1.5%) by standard culture techniques. In 13 (23.6%) of the 55, antibody-coated bacteria (ACB) were detected in the urine. The clinical, bacteriologic, radiologic and urinalysis findings in children with ACB were no different from those in children in whom the bacteria were not coated. Direct examination of uncentrifuged urine under high power revealed one or more bacteria per two high-power fields in 96% of infected urine samples and in only 7% of noninfected samples. Five or more leukocytes per high-power field in centrifuged urine were detected in 36.7% of infected urine samples but not in noninfected samples. The ACB test did not differentiate between asymptomatic bacteriuria with parenchymal scarring or vesicoureteral reflux or both and asymptomatic bacteriuria without these abnormalities.
mesh_terms: D000293:Adolescent; D000907:Antibodies, Bacterial / Q000652:urine*; D001419:Bacteria / Q000276:immunology* / Q000302:isolation & purification; D001437:Bacteriuria / Q000276:immunology* / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis; D008722:Methods; D008858:Microscopy, Phase-Contrast; D001745:Urinary Bladder Diseases / Q000175:diagnosis; D014556:Urine / Q000382:microbiology
chemical_list: D000907:Antibodies, Bacterial