title: Generalized transduction Of shigella flexneri by converting phage PE5.
abstract: Phage PE5, responsible for the conversion of type V antigen in Shigella flexneri, has the ability to produce generalized transduction. The correlation between phage multiplicity and the number of transductants, the specific inhibitory activity of anti-PE5 serum, and the lack of transduction in PE5 resistant recipients, indicate the role of phage PE5 in generalized transduction. Transduction of the R100-1 factor resulted in a non-transmissible tetracycline resistance segragation. The characteristics of the tetracycline resistance determinant suggest the possibility of integration.
mesh_terms: D000942:Antigens, Bacterial; D004352:Drug Resistance, Microbial; D005796:Genes; D008242:Lysogeny; D010641:Phenotype; D012483:Salmonella Phages / Q000254:growth & development / Q000276:immunology; D012763:Shigella flexneri / Q000187:drug effects / Q000276:immunology; D013752:Tetracycline / Q000494:pharmacology; D014161:Transduction, Genetic
chemical_list: D000942:Antigens, Bacterial; D013752:Tetracycline