Dextran uptake into, and loss from, corneas stored in intermediate-term preservative.
This investigation demonstrates that dextran passes into rabbit corneas stored in M-K medium prior to corneal transplantation. An equilibrium between dextran in the cornea and in the M-K medium is reached at about 24 hours. Post-keratoplasty dextran efflux is rapid with about 70 to 75 per cent being lost within one to three hours and 99 per cent being lost in 12 hours.
D000818:Animals; D002250:Carbon Radioisotopes; D003315:Cornea / Q000378:metabolism*; D016039:Corneal Transplantation; D003911:Dextrans / Q000378:metabolism*; D004727:Endothelium / Q000378:metabolism; D004848:Epithelium / Q000378:metabolism; D011817:Rabbits; D014021:Tissue Preservation; D014182:Transplantation, Autologous
D002250:Carbon Radioisotopes; D003911:Dextrans