Early complement components in NZB/NZW mice. I. The first component.
Sera from periodic bleedings of B/W female mice were assayed for C1 hemolytic activity. It peaked at 3 to 4 months of age and declined to very low levels by 6 to 7 months. Activity remained low even in long-lived animals.
D000818:Animals; D003172:Complement C1; D005260:Female; D007674:Kidney Diseases / Q000276:immunology; D051379:Mice; D008814:Mice, Inbred NZB; D013997:Time Factors
D003172:Complement C1