Induction of immunological memory in mice by RNA extract.
RNA extract isolated from spleens of mice immunized with lipopolysaccharide from E. coli induced an immunological memory in normal mice. Application of small amounts of corresponding antigen provoked a specific secondary immune response in RNA primed mice.
D000818:Animals; D004926:Escherichia coli; D005260:Female; D006385:Hemagglutination Inhibition Tests; D007156:Immunologic Memory; D008070:Lipopolysaccharides / Q000276:immunology*; D051379:Mice; D012313:RNA / Q000276:immunology*; D013154:Spleen / Q000276:immunology*
D008070:Lipopolysaccharides; D012313:RNA