Plasma renin activity, plasma angiotensin II and extracellular fluid volume in patients after renal transplantation.
1. Patients with cadaveric renal transplants and plasma creatinine less than 177 micronmol/l who had their own kidneys removed were studied. 2. The renin-angiotensin system appeared to behave in a normal fashion in response to alterations in sodium intake and posture. 3. The renin-angiotensin system had no major role in the establishment or maintenance of hypertension. 4. Mean arterial pressure was directly related to expansion of the extracellular fluid volume.
D000804:Angiotensin II / Q000097:blood*; D001794:Blood Pressure; D005110:Extracellular Space; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D012083:Renin / Q000097:blood*; D012964:Sodium / Q000652:urine; D014184:Transplantation, Homologous
D000804:Angiotensin II; D012964:Sodium; D012083:Renin