title: Synthesis of yeast histones in the cell cycle.
abstract: The yeast, Saccharomyces cerevisiae, contains four types of histones resembling histones H3, H2b, H2a, and H4 of animal cells. These proteins are synthesized primarily, if not exclusively, in the S-phase of the cell cycle. This result is discussed with reference to the insensitivity of ongoing DNA replication in yeast to inhibitors of protein synthesis.
mesh_terms: D002455:Cell Division; D002467:Cell Nucleus / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D004261:DNA Replication / Q000187:drug effects; D006657:Histones / Q000096:biosynthesis*; D006918:Hydroxyurea; D012441:Saccharomyces cerevisiae / Q000378:metabolism / Q000648:ultrastructure; D013997:Time Factors
chemical_list: D006657:Histones; D006918:Hydroxyurea