title: Optimal control of a semibatch fermentation.
abstract: This work is concerned with the optimization study of the semibatch fermentation by which an amino acid is produced. The particular fermentation studied is the synthesis of lysine by the auxotrophic mutant. Applying Green's theorem to the maximization problem was proposed, and it succeeded in determining the feed rate of the substrate that maximized the production rate of the desired product.
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D001419:Bacteria / Q000378:metabolism*; D001431:Bacteriological Techniques; D005285:Fermentation; D007700:Kinetics; D008239:Lysine / Q000378:metabolism; D008433:Mathematics; D008954:Models, Biological
chemical_list: D000596:Amino Acids; D008239:Lysine