Prophylaxis in urinary tract infection in children with myelomeningocele.
In 39 infants and children with myelomeningocele, no lower incidence of urinary tract infection was obtained by a trial of prophylaxis treatment with nitrofurantoin. Instead, nitrofurantoin-resistant strains appeared in some children, with the accompanying higher risk of re-infection.
D000293:Adolescent; D001424:Bacterial Infections / Q000150:complications / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008297:Male; D008591:Meningomyelocele / Q000150:complications*; D009582:Nitrofurantoin / Q000627:therapeutic use*; D012008:Recurrence; D016135:Spinal Dysraphism / Q000150:complications*; D014552:Urinary Tract Infections / Q000150:complications / Q000517:prevention & control*
D009582:Nitrofurantoin