Larynx injected with polytef paste.
A patient with inoperable lung cancer developed left-sided laryngeal paralysis. Her dysphonia, difficulty with swallowing, aspiration of secretions, and diminished cough reflex were improved with intracordal polytef injection for the remainder of her life. The foreign body reaction to the implant showed giant cells, few lymphocytes, and no polymorphonuclear leukocytes. This reaction may be described as a bland, chronic type consistent with the age of the implant. No areas of florid, acute reaction were found. Extrusion of part of the polytef through the cricothyroid space was observed. There were no signs of unfavorable tissue reaction, intolerance, or carcinogenicity. In a second case, part of the polytef paste exuded over the thyroid gland and was misinterpreted as a thyroid nodule. Excised 11 months after injection, the foreign body reaction appeared to be of a more acute type.
D000230:Adenocarcinoma / Q000150:complications; D000368:Aged; D001943:Breast Neoplasms / Q000150:complications; D002283:Carcinoma, Bronchogenic / Q000150:complications; D003680:Deglutition Disorders / Q000209:etiology / Q000628:therapy; D005260:Female; D005549:Foreign-Body Reaction / Q000473:pathology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000209:etiology; D007830:Larynx / Q000187:drug effects* / Q000473:pathology; D008175:Lung Neoplasms / Q000150:complications; D008875:Middle Aged; D011138:Polytetrafluoroethylene / Q000009:adverse effects / Q000627:therapeutic use*; D014826:Vocal Cord Paralysis / Q000628:therapy*
D011138:Polytetrafluoroethylene