title: Substrate metabolism and renal function.
abstract: Glucose metabolism is related to two major renal functions. Glycolysis may be related to an energy requiring function--fine adjustment of renal sodium absorption. Gluconeogenesis may be related to controlling intracellular pH and salvation of energy otherwise wasted in acidosis. Ammoniagenesis is related to gluconeogenesis in the metabolic acidosis, but the individual phenomena are not necessarily dependent on each other.
mesh_terms: D000042:Absorption; D000136:Acid-Base Equilibrium; D000138:Acidosis / Q000378:metabolism; D000641:Ammonia / Q000378:metabolism; D000818:Animals; D003641:Deamination; D004734:Energy Metabolism / Q000187:drug effects; D004976:Ethacrynic Acid / Q000494:pharmacology; D005227:Fatty Acids / Q000378:metabolism; D005665:Furosemide / Q000494:pharmacology; D005943:Gluconeogenesis; D005947:Glucose / Q000378:metabolism; D005973:Glutamine / Q000378:metabolism; D006019:Glycolysis / Q000187:drug effects; D006801:Humans; D007668:Kidney / Q000502:physiology*; D007684:Kidney Tubules / Q000378:metabolism; D007773:Lactates / Q000378:metabolism; D012964:Sodium / Q000378:metabolism
chemical_list: D005227:Fatty Acids; D007773:Lactates; D005973:Glutamine; D000641:Ammonia; D005665:Furosemide; D012964:Sodium; D005947:Glucose; D004976:Ethacrynic Acid