[Kinetics of the immune response following syngenous transfer of bone marrow, thymus and spleen cells from donors under the influence of previously administered antigen].
The influence of the donor priming upon the recipient's immune response under conditons of syngenic transfer of nucleated cells of the bone marrow, thymus, spleen to the lethally irradiated recipients was studied, the recipients being immunized with sheep erythrocytes. A fall of total number of antibody-forming cells was observed in the recipients in priming. The number of hemolytic foci was increased the first day after priming in case of injection of the bone marrow cells from the intact donors and of the thymus cells from the immunized donors. On the third day of the experiment the number of these foci was three time less in comparison with the control. An increase of the hemolytic foci was discovered in the syngenic transfer of splenic cells affected by priming.
D000818:Animals; D000921:Antibody-Producing Cells; D001853:Bone Marrow / Q000276:immunology*; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D007108:Immune Tolerance; D007117:Immunization, Secondary; D051379:Mice; D008808:Mice, Inbred CBA; D013154:Spleen / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology* / Q000637:transplantation; D014181:Transplantation Immunology; D014184:Transplantation, Homologous
Kinetika immunnogo otveta pri sigennom perenose kletok kostnogo mozga, timusa i selezenk ot donorov pod vozdeĭstviem predvaritel'no vvedennogo im antigena