Inflammatory factors produced by sensitized guinea-pig peripheral blood lymphocytes.
The supernatants obtained from stimulated tuberculin-sensitive guinea-pig peripheral blood lymphocytes contain factors that induce a cutaneous inflammatory response in normal guinea-pigs similar to the tuberculin reaction and inhibit the migration of normal guinea-pigs peritoneal exudate cells. There appears to be a correlation between the presence of in vitro migration inhibitory activity and inflammatory activity in vivo.
D000818:Animals; D001500:BCG Vaccine; D002478:Cells, Cultured; D006168:Guinea Pigs; D007249:Inflammation / Q000209:etiology*; D007271:Injections, Intradermal; D008214:Lymphocytes / Q000378:metabolism*; D008222:Lymphokines / Q000378:metabolism; D008263:Macrophage Migration-Inhibitory Factors / Q000378:metabolism; D009163:Mycobacterium bovis / Q000276:immunology; D012867:Skin / Q000276:immunology; D014373:Tuberculin
D001500:BCG Vaccine; D008222:Lymphokines; D008263:Macrophage Migration-Inhibitory Factors; D014373:Tuberculin