Circulating antibodies in cutaneous leishmaniasis: their detection by immunofluorescence.
With the use of an indirect fluorescent antibody (IFA) test and freeze-dried antigens, circulating antibody titres of 1 in 100 or above to Leishmania tropica leptomonad forms were detected in 66-6% and 76-2% of 18 patients with active and 21 patients with healed cutaneous leishmaniasis, respectively. Cross-reactivity was observed with L. donovani and Trypanosoma cruzi antigens. Five out of 15 patients with active pulmonary tuberculosis had antibodies to L. tropica major, suggesting a possible cross-reactivity between the two agents.
D000906:Antibodies / Q000302:isolation & purification*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007891:Leishmania / Q000276:immunology*; D007896:Leishmaniasis / Q000276:immunology*
D000906:Antibodies