title: Treatment of Behcet's disease with chlorambucil.
abstract: Five patients with Behcet's disease in the active and progressive stages were treated with chlorambucil (Leukeran). In all aptients a long-lasting remission was obtained, the ocular lesions did not progress and the vision did not deteriorate. Follow-up varied between 10 and 24 months. Results were encouraging and the form of treatment with chlorambucil and small doses of corticosteroids was superior to other forms of therapy.
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000188:drug therapy*; D002699:Chlorambucil / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D008297:Male; D008875:Middle Aged; D012075:Remission, Spontaneous; D014792:Visual Acuity
chemical_list: D002699:Chlorambucil