title: Evidence for an association between univalent Y chromosomes and spermatoycte loss in XYY mice and men.
abstract: It has been observed previously that there is an association between sex chromosome pairing failure during meiosis and spermatocyte death. An hypothesis is advanced suggesting a similar association between a disruption of sex chromosome pairing (specifically, a failure of Y chromosome pairing) and spermatocyte loss in XYY mice and men.
mesh_terms: D000818:Animals; D006801:Humans; D008297:Male; D008540:Meiosis; D008677:Metaphase; D051379:Mice; D008954:Models, Biological; D012729:Sex Chromosome Aberrations / Q000473:pathology*; D012730:Sex Chromosomes; D013090:Spermatocytes; D013091:Spermatogenesis; D013094:Spermatozoa; D014997:XYY Karyotype / Q000235:genetics / Q000473:pathology*; D014998:Y Chromosome