title: A randomized controlled trial of vitamin C in the prevention and amelioration of the common cold.
abstract: A randomized controlled trial of the effect of 1 g ascorbic acid per day in the prevention of the common cold was conducted on 688 adult women. There is evidence of a small reduction by vitamin C in the mean number of chest colds, but no evidence of any effect on simple colds. The existence of a subgroup of vulnerable women in the community who benefit from vitamin C was considered but further examination of the data gives no support to this conclusion.
mesh_terms: D000328:Adult; D001205:Ascorbic Acid / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003139:Common Cold / Q000517:prevention & control*; D003371:Cough / Q000517:prevention & control; D005260:Female; D006801:Humans; D010919:Placebos; D013997:Time Factors
chemical_list: D010919:Placebos; D001205:Ascorbic Acid