title: Human gonadotropins: biochemical, immunological, and clinical aspects.
abstract: Methodologies for the extraction of both pituitary and urinary gonadotropins are described. The chemical composition of some of the gonadotropins is discussed, and the significance of the subunit structures is reviewed. Immunological properties of the gonadotropins are discussed from the standpoint of antisera and procedures involving radioimmunoassay. Finally, certain clinical conditions which are characterized by fluctuations in gonadotropin levels are discussed.
mesh_terms: D000595:Amino Acid Sequence; D006063:Chorionic Gonadotropin / Q000032:analysis / Q000276:immunology / Q000378:metabolism; D002996:Clomiphene / Q000494:pharmacology; D004700:Endocrine System Diseases / Q000378:metabolism; D004967:Estrogens / Q000494:pharmacology; D005260:Female; D005640:Follicle Stimulating Hormone / Q000032:analysis / Q000276:immunology / Q000378:metabolism; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology; D006062:Gonadotropins / Q000627:therapeutic use; D006801:Humans; D007106:Immune Sera; D007246:Infertility / Q000188:drug therapy; D007986:Luteinizing Hormone / Q000032:analysis / Q000276:immunology / Q000378:metabolism; D008297:Male; D008968:Molecular Conformation; D008970:Molecular Weight; D011863:Radioimmunoassay; D013091:Spermatogenesis
chemical_list: D006063:Chorionic Gonadotropin; D004967:Estrogens; D006062:Gonadotropins; D007106:Immune Sera; D002996:Clomiphene; D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone