[Goodpasture's syndrome. A new case].
The authors report a new observation of Goodpasture's syndrome in a 21 years old patient. Diagnosis was made by renal biopsy after discovering, by immunofluorescence techniques, linear deposits of IgG and C3 on the renal basal lamina. Anti-basal lamina antibodies of the plasma were not found. In spite of therapy by steroids, a rapid worsening of renal functions accompanied a nephrotic syndrome. Supplementing hemodialysis helped patients to survive without recurrence of hemoptysis. Heparinotherapy prescribed on the creation of an arteriovenous fistula seemed to have brought a temporary improvement of the renal function.
D000328:Adult; D000747:Anemia, Hypochromic / Q000209:etiology; D019867:Anti-Glomerular Basement Membrane Disease / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D000936:Antigen-Antibody Complex; D001485:Basement Membrane / Q000276:immunology / Q000648:ultrastructure; D003176:Complement C3; D005455:Fluorescent Antibody Technique; D005921:Glomerulonephritis / Q000209:etiology; D006469:Hemoptysis / Q000209:etiology; D006801:Humans; D007074:Immunoglobulin G; D007678:Kidney Glomerulus / Q000276:immunology / Q000648:ultrastructure; D008297:Male; D011507:Proteinuria / Q000209:etiology; D011650:Pulmonary Alveoli / Q000276:immunology
D000936:Antigen-Antibody Complex; D003176:Complement C3; D007074:Immunoglobulin G
Syndrome de Goodpasture. Une nouvelle observation