Enterochromaffin cells as the endocrine source of gastrointestinal substance P.
Immunoreactive Substance P is localized in the intramural neural plexuses of mammalian intestine, and in endocrine cells in the intestinal mucosa which have now been identified as enterochromaffin (EC). The presence of a neurotransmitter peptide in these cells favours the hypothesis of their neuroectodermal origin.
D000818:Animals; D002838:Chromaffin System / Q000032:analysis*; D004759:Enterochromaffin Cells / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007124:Immunoenzyme Techniques; D011817:Rabbits; D013373:Substance P / Q000032:analysis*
D013373:Substance P