Presence of proline in position 3 for potent inhibition of the activity of the luteinizing hormone releasing hormone and of ovulation.
D000818:Animals; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives* / Q000494:pharmacology; D007986:Luteinizing Hormone / Q000378:metabolism*; D010060:Ovulation / Q000187:drug effects*; D010902:Pituitary Gland / Q000187:drug effects / Q000378:metabolism*; D011392:Proline; D051381:Rats; D013329:Structure-Activity Relationship
D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D011392:Proline