title: Diagnosis of cryptococcal meningitis.
abstract: In a patient with progressive neurological deterioration, multiple lumbar CSF studies and extensive serological testing failed to demonstrate cryptococcal infection, while a single cisternal puncture produced viable cryptococcal organisms.
mesh_terms: D000908:Antibodies, Fungal / Q000032:analysis; D000946:Antigens, Fungal / Q000032:analysis; D002908:Chronic Disease; D002946:Cisterna Magna / Q000382:microbiology*; D003453:Cryptococcosis / Q000175:diagnosis*; D003454:Cryptococcus / Q000302:isolation & purification*; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008581:Meningitis / Q000175:diagnosis*; D008722:Methods; D008875:Middle Aged
chemical_list: D000908:Antibodies, Fungal; D000946:Antigens, Fungal