title: [Condition of microflora of the nasopharynx in immunization with live influenza vaccine for oral administration].
abstract: The authors present data concerning the state of the microflora of the nasopharynx in the immunization of adults and schoolchildren with the living influenza vaccine for oral administration. During the vaccinal process there occurred qualitative changes in the microbial pattern of the nasopharynx and a reduction in the level of the salivary lysozyme. The most pronounced changes were seen after the first vaccination, when the seeding efficiency of the pathogenic staphylococcus the E. coli and the Pr. mirabilis increased considerably. At the same time the incidence of isolation of the pathogenic staphylococcus, neisseria, and hemolytic streptococcus was decreased. The mentioned changes in the microbial flora directly depended on the dynamics of the survival of the vaccine influenza virus.
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D002648:Child; D003352:Corynebacterium / Q000302:isolation & purification; D004926:Escherichia coli / Q000302:isolation & purification; D005658:Fungi / Q000302:isolation & purification; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage*; D007709:Klebsiella / Q000302:isolation & purification; D009113:Muramidase / Q000378:metabolism; D009305:Nasopharynx / Q000382:microbiology*; D009343:Neisseria / Q000302:isolation & purification; D011513:Proteus mirabilis / Q000302:isolation & purification; D012463:Saliva / Q000201:enzymology; D013045:Species Specificity; D013210:Staphylococcus / Q000302:isolation & purification; D013291:Streptococcus / Q000302:isolation & purification
chemical_list: D007252:Influenza Vaccines; D009113:Muramidase
vernacular_title: Sostoianie mikroflory nosoglotki pri immunizatsii zhivoi grippoznoi vaktsinoi dlia peroral'nogo vvedeniia