Genetics of the +p9 syndrome.
An analysis of data about the +p9 syndrome revealed that this clinical entity may occur in some different genetic forms. The recurrence risk in cases with familial translocations is due to the type of meiotic segregation, 2:2 or 3:1. It was shown a nonrandomness of involvement of chromosomes 15 and 22 in translocations with chromosome number 9.
D000022:Abortion, Spontaneous / Q000235:genetics; D000367:Age Factors; D001724:Birth Weight; D002901:Chromosomes, Human, 13-15; D002904:Chromosomes, Human, 21-22 and Y; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D008540:Meiosis; D010290:Parents; D010375:Pedigree; D010641:Phenotype; D011247:Pregnancy; D012737:Sex Factors; D014178:Translocation, Genetic; D014314:Trisomy