title: A controlled trial of ketoprofen (administered rectally) in arthritis of the hip and knee.
abstract: A double-blind therapeutic trial carried out by the sequential method has demonstrated clearly a significant difference in efficacy between ketoprofen (given rectally at a dosage of 200 mg daily) and a placebo in a group of patients suffering from osteoarthritis of the hip or knee. The interest in this type of study lies in the fact that it will often given the answer to a simple question using a relatively small number of patients.
mesh_terms: D000368:Aged; D000700:Analgesics; D000893:Anti-Inflammatory Agents; D001168:Arthritis / Q000188:drug therapy*; D001577:Benzophenones / Q000008:administration & dosage*; D002986:Clinical Trials as Topic; D005260:Female; D006621:Hip Joint; D006801:Humans; D007660:Ketoprofen / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D010919:Placebos; D013488:Suppositories
chemical_list: D000700:Analgesics; D000893:Anti-Inflammatory Agents; D001577:Benzophenones; D010919:Placebos; D013488:Suppositories; D007660:Ketoprofen