Gonadotropin and sex steroid response to luteinizing hormone-releasing hormone in patients with premature adrenarche.
Luteinizing hormone-releasing hormone (100 mug iv) produced a response of LH, FSH, testosterone, and estradiol in children with premature pubarche that was not different from that among normal prepubertal children. Hence, this study provides no evidence that hypothalamic-pituitary-gonadal maturation occurs with the onset of premature sexual hair.
D000311:Adrenal Glands / Q000254:growth & development*; D002648:Child; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D006197:Hair; D006801:Humans; D007031:Hypothalamus / Q000254:growth & development; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010902:Pituitary Gland / Q000254:growth & development; D011627:Puberty; D011629:Puberty, Precocious; D011863:Radioimmunoassay; D013737:Testis; D013739:Testosterone / Q000097:blood
D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone