title: Production of leucocyte migration inhibitory factor by neonatal lymphocytes.
abstract: Lymphocytes (mononuclear cells) from cord blood of 10 normal placentas and from 10 normal adults were assessed for production of leucocyte migration inhibiting factor (LIF) after phytohaemagglutinin (PHA) stimulation, as a measure of cell-mediated immunity. Mononuclear cells from both adult and cord blood produced adequate quantities of LIF, indicating that neonatal lymphocytes have the ability to manufacture normal amounts of lymphokines.
mesh_terms: D000328:Adult; D005312:Fetal Blood / Q000166:cytology; D006801:Humans; D066298:In Vitro Techniques; D007231:Infant, Newborn; D037102:Lectins / Q000494:pharmacology; D007962:Leukocytes / Q000502:physiology*; D008214:Lymphocytes / Q000378:metabolism*; D008263:Macrophage Migration-Inhibitory Factors / Q000096:biosynthesis*; D013268:Stimulation, Chemical
chemical_list: D037102:Lectins; D008263:Macrophage Migration-Inhibitory Factors