title: Impact of cephalosporin prophylaxis on conization-vaginal hysterectomy morbidity.
abstract: A prospective, randomized, double-blind evaluation of Loridine-Keflex prophylaxis in a homogeneous group of 32 patients undergoing sequential cervical conization and vaginal hysterectomy is reported. There was no infectious or febrile morbidity in the 18 oatuebts receuvubg abtubuitucs, Morbidity occurred in six of 14 patients receiving placebos (P is less than 0.05). Antibiotic prophylaxis and conization-hysterectomy morbidity are discussed.
mesh_terms: D000328:Adult; D001706:Biopsy; D002511:Cephalosporins / Q000627:therapeutic use*; D002584:Cervix Uteri / Q000601:surgery*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007045:Hysterectomy, Vaginal; D008875:Middle Aged; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000601:surgery
chemical_list: D002511:Cephalosporins