title: Regulation of the ilv 1 multifunctional gene in Saccharomyces cerevisiae.
abstract: The ilv 1 gene in S. cerevisiae codes for a regulatory protein involved in depression of the ilv 2 and ilv 3 genes as well as a biosynthetic enzyme, threonine deaminase. 2. The ilv 1 gene does not autogenously regulate its catalytic product threonine deaninase. 3. Regulation of the ilv 2 and ilv 3 gene products involve different aporepressors than regulation of the ilv 1 gene product. 4. The ilv I multifunctional gene in S. cerevisiae may be a duplication and fusion of a bacterial like ilv 1 gene where ilv 1 catalytic and regulatory function have been differentially conserved.
mesh_terms: D002874:Chromosome Mapping; D005656:Fungal Proteins / Q000096:biosynthesis*; D005796:Genes; D005809:Genes, Regulator; D006836:Hydro-Lyases / Q000378:metabolism*; D007532:Isoleucine / Q000378:metabolism; D007930:Leucine / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000502:physiology; D013913:Threonine Dehydratase / Q000378:metabolism*; D014633:Valine / Q000378:metabolism
chemical_list: D005656:Fungal Proteins; D007532:Isoleucine; D006836:Hydro-Lyases; D013913:Threonine Dehydratase; D007930:Leucine; D014633:Valine