title: [State of certain indices of natural, nonspecific immunity in workers engaged in the manufacture of neomycin and monomycin].
abstract: Women occupied at various stages of neomycin and monomycin production were examined immunologically. The examination revealed insignificant changes in the phagocytic activity of the blood neutrophils, however no relation between the changes level and the level of contact with the antibiotics was observed. Changes in composition of the microflora in the deep skin layers in direction of an increase in the number of pathogenic microbes and a decrease in the bactericidal function of the skin were found in the women occupied at the final stages of the technological process, i.e. drying, packing and control.
mesh_terms: D004345:Drug Industry; D015643:Erythromycin Ethylsuccinate / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007109:Immunity / Q000187:drug effects*; D009355:Neomycin / Q000009:adverse effects*; D009504:Neutrophils / Q000276:immunology; D009784:Occupational Diseases / Q000139:chemically induced / Q000276:immunology*; D010587:Phagocytosis / Q000187:drug effects; D012867:Skin / Q000382:microbiology; D014586:USSR
chemical_list: D015643:Erythromycin Ethylsuccinate; D009355:Neomycin
vernacular_title: Sostoianie nekotorykh pokazateleĭ estestvennogo nespetsificheskogo immuniteta u rabochikh, zaniatykh na proizvodstve neomitsina i monomitsina