Human centromere mapping using teratoma data.
Under the assumption that benign ovarian teratomas arise parthenogenetically from a germ cell by suppression of the second meiotic division, the proportion gamma of heteratomas collected from heterozygous hosts is a measure for the distance between the corresponding gene and its centromere. For proportions gamma less than or equal to 0.3, the mapping function x = gamma/2 applies, where x is the map distance in Morgans.
D002478:Cells, Cultured; D002874:Chromosome Mapping; D005260:Female; D005821:Genetic Techniques; D006801:Humans; D008433:Mathematics; D010051:Ovarian Neoplasms / Q000235:genetics; D013724:Teratoma / Q000235:genetics