[Clinical study of the normothymic effect of dipropylacetamide].
On the basis of his results, obtained during a long term study of 32 patients presenting cyclic variations of mood with a known frequency, the author concludes that dipropylacetamide permits to stabilise mood in about 70% of all cases through a supression of relapses or by reducing significantly their frequency. No biological changes were observed and the clinical tolerance of the drug was excellent in most cases. This drug constitutes a variable alternative to lithium treatment, and lacks the well known lithium side effects and limitations.
D000293:Adolescent; D000328:Adult; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008094:Lithium / Q000627:therapeutic use; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy*; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D014631:Valerates / Q000627:therapeutic use*; D014635:Valproic Acid / Q000009:adverse effects / Q000031:analogs & derivatives / Q000627:therapeutic use*
D011619:Psychotropic Drugs; D014631:Valerates; D014635:Valproic Acid; D008094:Lithium; C004651:dipropylacetamide
Etude clinique de l'effet normothymique du dipropylacetamide