[Electrophoretic mobility of peripheral lymphocytes and Hodgkin's erythrocytes. Correlation with some clinical, hematological and immunological parameters of the disease].
In 32 patients with Hodgkin's disease the electrophoretic mobility of peripheral blood lymphocytes and, at the same time, some clinical, hematological, and immunological parameters of the disease were determined. The mean mobility of lymphocytes was normal; nevertheless, the lymphocytic mobility of 8/32 patients was significantly decreased. No correlation with clinical, hematological, and immunological parameters of the disease was detected. However, the functional deficiency of hodgkinian T lymphocytes seems to play a  role in their abnormal electrophoretic behaviour. In 9 out of these 32 patients the electrophoretic mobility of peripheral erythrocytes was also determined. The average mobility was significantly (P less than 0.05) decreased. No correlation with clinical, hematological, and immunological parameters nor with electrophoretic mobility of lymphocytes was detected.
D000912:Antibodies, Neoplasm; D000917:Antibody Formation; D004586:Electrophoresis; D004912:Erythrocytes / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006689:Hodgkin Disease / Q000097:blood* / Q000276:immunology; D006801:Humans; D007136:Immunoglobulins; D037102:Lectins; D008213:Lymphocyte Activation; D013601:T-Lymphocytes / Q000276:immunology
D000912:Antibodies, Neoplasm; D007136:Immunoglobulins; D037102:Lectins
Mobilita' elettroforetica di linfociti periferici ed erithrociti Hodgkiniani. Correlazione con alcuni parametri clinici, ematologici ed immunologici della malattia