Inducible, error-free DNA Repair in tsl recA mutants of E. coli.
Host of cell reactivation and UV reactivation and  mutagenesis of UV-irradiated phage mu were measured in tsl recAplus and tsl recA host mutants. Host cell reactivation was slightly more efficient in the tsl recA strain. Phage was UV-reactivated in the tsl recA strain with about one-half the efficiency of that in the wild type strain, but there was no corresponding mutagenesis of phage. UV-reactivation was also slightly lower and mutagenesis several-fold lower than normal in the tsl recAplus strain. To account for these observations, we propose that there is an inducible, error-free pathway of DNA repair in E. coli that competes with error-prone repair for repair of phage lesions.
D003090:Coliphages / Q000528:radiation effects*; D004260:DNA Repair; D004267:DNA Viruses; D004926:Escherichia coli / Q000378:metabolism* / Q000528:radiation effects; D009154:Mutation; D011831:Radiation Genetics; D013045:Species Specificity; D014466:Ultraviolet Rays