title: [Changes in the concentration of estradiol in the peripheral blood of immature female rats following intrahypothalamic administration of a factor liberating luteinizing hormone].
abstract: Administration of a synthetic luteinizing hormone-releasing factor (LH-RF) into the area of the medial eminence and the third ventricle of the sexually immature female rats, aged 20-22 days, caused a distinct increase in the estradiol concentration in the peripheral blood of the majority of these animals. Administration of physiological solution produced a reaction (much weaker) only in a small percentage of the animals. There was no increase in estradiol level when LH-RF got into the other areas of the hypothalamus.
mesh_terms: D000818:Animals; D001931:Brain Mapping; D004958:Estradiol / Q000097:blood*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D007031:Hypothalamus / Q000187:drug effects*; D008473:Median Eminence / Q000187:drug effects; D051381:Rats; D012741:Sexual Maturation
chemical_list: D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol
vernacular_title: Izmenenie kontsentratsii éstradiola v perifericheskoĭ krovi nepolovozrelykh samok krys pri vnutrigipotalamicheskom vvedenii faktora, vysvobodaiushchego liuteiniziruiushchiĭ gormon