title: [Sterilization by ionizing radiations (author's transl)].
abstract: The first part summarizes the general characteristics of ionizing radiations and their activity on microorganisms: lethal and mutagenic effects, sensitivity conditions. Different microbial species have different sensitivities: gram negative bacteria are more sensitive (D10 approximately 5-10 Krads), bacterial spores and viruses are more resistant (D10 approximately 1 Megarads). The second part considers the main applications of radiosterilization: some are at present in full development (medical and surgical disposable equipment); others are still at the experimental stage. Practical aspects, determination of sterilizing doses and control of radiosterilization are also described.
mesh_terms: D001419:Bacteria / Q000528:radiation effects*; D004209:Disposable Equipment; D005514:Food Irradiation; D005658:Fungi / Q000528:radiation effects*; D006088:Gram-Negative Aerobic Bacteria / Q000528:radiation effects; D006801:Humans; D008835:Micrococcaceae / Q000528:radiation effects; D009154:Mutation; D009159:Mycobacteriaceae / Q000528:radiation effects; D004364:Pharmaceutical Preparations; D011839:Radiation, Ionizing; D013242:Sterilization / Q000379:methods*; D013289:Streptococcaceae / Q000528:radiation effects; D013523:Surgical Equipment; D014612:Vaccines; D014780:Viruses / Q000528:radiation effects*
chemical_list: D004364:Pharmaceutical Preparations; D014612:Vaccines
vernacular_title: La stérilisation par les rayonnements ionisants