[Effects of Candida albicans on wound-healing in an animal model (author's transl)].
The effects of Candida albicans on the healing of experimental wounds in rats was investigated. Granulation tissue developing in implated polyvinylchloride chambers was quantified. The amount of granulation tissue in the yeast-contaminated wounds is significantly less in comparison to controls. The inhibitory effect is directly proprotional to the amount of inoculated yeasts and dependes on the presence of living yeast cells. The repair of ulcers is supposedly retarded by yeast contamination, as has been suggested previously by clinical observation.
D000818:Animals; D002176:Candida albicans / Q000502:physiology*; D004195:Disease Models, Animal; D006097:Granulation Tissue / Q000382:microbiology; D007871:Leg Ulcer / Q000382:microbiology; D008297:Male; D011143:Polyvinyl Chloride; D051381:Rats; D014945:Wound Healing; D014946:Wound Infection
D011143:Polyvinyl Chloride
Tierexperimentelle Untersuchungen zur Beeinflussung der Wundheilung durch Candida albicans