title: [Metabolism of collagen in progressive scleroderma and dermatomyositis].
abstract: The biosynthesis of collagen was studied in skin of healthy subjects and patients with progressive sclerodermia and dermatomyositis. The incorporatione of radioactive precursors (14C-proline), the rate of so-called collage-like-protein in sera, and the excretion of hydroxyprolin in urine depended on the severity of the dermatomyositis in progressive sclerodermia.
mesh_terms: D001798:Blood Proteins / Q000032:analysis; D055598:Chemical Phenomena; D002621:Chemistry; D003094:Collagen / Q000096:biosynthesis / Q000378:metabolism*; D003882:Dermatomyositis / Q000378:metabolism* / Q000473:pathology / Q000652:urine; D006801:Humans; D006909:Hydroxyproline / Q000652:urine; D008875:Middle Aged; D011509:Proteoglycans / Q000096:biosynthesis; D012595:Scleroderma, Systemic / Q000378:metabolism* / Q000473:pathology; D012867:Skin / Q000378:metabolism
chemical_list: D001798:Blood Proteins; D011509:Proteoglycans; D003094:Collagen; D006909:Hydroxyproline
vernacular_title: Der Kollagenstoffwechsel bei progressiver Sklerodermie und Dermatomyositis