Immunosuppressive effect of a mouse placenta fraction on H-2 incompatible split heart allografts.
A soluble placenta fraction from mice (A.CA) mated with H-2 histoincompatible males (A/Sn) significantly prolonged the survival of heterotopic A/Sn heart transplants in A.CA recipients. No prolongation of A/Sn heart graft survival was obtained with the corresponding A.CA placenta fraction after A.CA X A.CA mating.
D000818:Animals; D005260:Female; D016027:Heart Transplantation; D006649:Histocompatibility Antigens; D007165:Immunosuppression Therapy; D008297:Male; D051379:Mice; D010920:Placenta / Q000502:physiology*; D011247:Pregnancy; D014020:Tissue Extracts / Q000494:pharmacology; D014184:Transplantation, Homologous
D006649:Histocompatibility Antigens; D014020:Tissue Extracts