title: B- and T-cell markers on human lymphoblasts after stimulation with mitogen or antigens.
abstract: Receptors for sheep erythrocytes and for the third component of complement were demonstrated on human lymphoblasts after stimulation with various antigens and mitogens. With these markers B- and T-cell stimulation could be differentiated. Phytohaemagglutinin (PHA) and purified protein derivative (PPD) proved to activate predominantly T cells, whereas foetal calf serum (FCS) was shown to be a B-cell stimulator. Candida albicans and allogeneic cells, on the other hand, stimulated both B and T cells.
mesh_terms: D000941:Antigens; D000946:Antigens, Fungal; D001402:B-Lymphocytes / Q000276:immunology*; D001666:Binding Sites, Antibody; D002176:Candida albicans / Q000276:immunology; D002462:Cell Membrane / Q000276:immunology; D003165:Complement System Proteins; D006801:Humans; D037102:Lectins; D008213:Lymphocyte Activation; D008934:Mitogens / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000276:immunology*; D014373:Tuberculin
chemical_list: D000941:Antigens; D000946:Antigens, Fungal; D037102:Lectins; D008934:Mitogens; D014373:Tuberculin; D003165:Complement System Proteins