[A new antigen induced by oncornavirus D in mouse fibroblast culture].
It was established by the CFT and immunofluorescence that oncornavirus D inoculated into continuous mouse fibroblast cultures induced in them a new antigen differing from those of the virus and of the original non-infected cells. The antigen was shown to accumulate during cultivation of the infected cells. No antigen was induced by oncornavirus inactivated by heating or neutralized by antiviral antiserum. The physico-chemical and immunological properties of the new antigen experimentally induced in the mouse fibroblast culture are identical to those of the new antigen present in cultures of human J-96, HeLa and HEp-2 cells.
D000818:Animals; D000951:Antigens, Neoplasm / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D002460:Cell Line; D003168:Complement Fixation Tests; D005455:Fluorescent Antibody Technique; D006358:Hot Temperature; D006801:Humans; D007106:Immune Sera; D007739:L Cells; D051379:Mice; D009858:Oncogenic Viruses / Q000254:growth & development* / Q000276:immunology
D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D007106:Immune Sera
Novyĭ antigen, indutsirovannyĭ onkornavirusom D v kul'ture fibroblastov myshi