Preliminary report: effects of female sex hormones on insulin secretion by the perfused rat pancreas.
The effects of progesterone and oestradiol on insulin secretion were studied with the perfused pancreas technic. 1. Progesterone did not affect-glucose induced insulin secretion directly. 2. OEstradiol increased insulin secretion directly.
D000818:Animals; D004958:Estradiol / Q000494:pharmacology; D004967:Estrogens / Q000494:pharmacology*; D005260:Female; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects*; D011247:Pregnancy; D011374:Progesterone / Q000494:pharmacology*; D051381:Rats; D012636:Secretory Rate / Q000187:drug effects
D004967:Estrogens; D007328:Insulin; D011374:Progesterone; D004958:Estradiol