title: Genetic and biochemical studies on mannose-negative mutants with colonial morphological alterations.
abstract: Four mannose mutants of Saccharomyces cerevisiae are described. In addition to their inability to grow on mannose as sole carbon and energy source, the mutants exhibit a distinct colonial morphological alteration. The isolates form hard colonies when grown on agar and exhibit extreme flocculation in broth. These organisms can catabolize mannose, but only form one-half the mannan found in the wild-type yeasts.
mesh_terms: D002455:Cell Division; D005796:Genes; D006593:Hexokinase / Q000378:metabolism; D008358:Mannose / Q000378:metabolism*; D009154:Mutation; D010641:Phenotype; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism*
chemical_list: D006593:Hexokinase; D008358:Mannose