title: [Effects of lowly dosed gestagen pill Exlutona on carbohydrate and fat metabolism (author's transl)].
abstract: Due to the precautions stopping of megestrol containing oral contraceptives the prescription of oral contraceptives has again become problematic. Oral contraceptives taken over a longer period can cause occasionally side effects which then cause a stopping of these medicaments. In order to get a survey of possible effects on the carbohydrate and fat metabolism 60 patients at the age of 16-26 years who had not been pregnant were observed over a longer period and their laboratory parameters (serum insulin, triglycerides, cholesterol, total lipids) were controlled. Significant changes were only found in the total lipids in the sense of a reduction of the total lipid level. A marked reduction was found with the triglycerides. Basing on these results and taking into consideration the occasionally occurring menstrual irregularity this lowly dosed gestagen pill Exlutona can be recommended not only to young girls but also to patients who often suffer from a relative contraindication because of adiposity, hypertension and subclinical diabetes.
mesh_terms: D000293:Adolescent; D000328:Adult; D050260:Carbohydrate Metabolism; D002784:Cholesterol / Q000097:blood; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood; D008234:Lynestrenol / Q000009:adverse effects / Q000494:pharmacology*; D014280:Triglycerides / Q000097:blood
chemical_list: D007328:Insulin; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol; D008234:Lynestrenol
vernacular_title: Auswirkungen der Minigestagenpille (Exlutona) auf Kohlenhydrat- und Fettstoffwechsel