The effect of chlorhexidine mouthrinse on healing after gingivectomy.
The purpose of this investigation was to evaluate the effect of 0.2% chlorhexidine gluconate mouthrinse following gingivectomy on plague under the dressing and on healing. Twenty-eight patients with indications for gingivectomy were selected. Coe-Pak was used as surgical dressing. In addition to unsual home care, the patients rinsed twice daily with chlorhexidine or placebo for 21 d after surgery. The study followed a cross-over double-blind design. Gingival exudate was assessed and Pl I and G I were registered at 7, 14, and 21 d postsurgically. The study indicated that chlorhexidine did not influence the amount of plaque under the dressing, and it was uncertain whether chlorhexidine had any effect on the healing process when the surgical area was covered by Coe-Pak. However, (1) after the surgical dressing was removed, the chlorhexidine maintained plaque scores at the same low level as under the dressing, (2) healing was was promoted when chlorhexidine was used, and (3) the presence of a dressing in one side of the mouth did not prevent the patient from maintaining good oral hygiene.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001645:Biguanides / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003773:Dental Plaque / Q000187:drug effects*; D004341:Drug Evaluation; D005260:Female; D005883:Gingival Crevicular Fluid / Q000187:drug effects; D005890:Gingivectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes; D010511:Periodontal Dressings; D011182:Postoperative Care; D014945:Wound Healing / Q000187:drug effects*
D001645:Biguanides; D009067:Mouthwashes; D002710:Chlorhexidine