A controlled trial of the analgesic effects of Floctafenine against placebo in osteoarthrosis.
Floctafenine 200 mg four times a day was compared with placebo in 30 out-patients with osteoarthrosis in a double-blind controlled study. There was a significant patient preference for, and a greater relief of pain with, floctafenine. Pain on walking and joint stiffness after sitting were significantly less on floctafenine. There were no differences in side-effects between floctafenine and placebo.
D000328:Adult; D000368:Aged; D062365:Aminobenzoates / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy* / Q000473:pathology; D011804:Quinolines / Q000009:adverse effects / Q000627:therapeutic use*
D062365:Aminobenzoates; D000894:Anti-Inflammatory Agents, Non-Steroidal; D011804:Quinolines