UV sensitivity of a nonrepressor regulatory protein of bacteriophage P22.
The product of phage P22 gene c1 has two functions: it promotes synthesis of P22 repressor and it retards expression of some lytic genes. We present evidence that this product is inactivated in UV-irradiated hosts. The conditions for inactivation of c1 product include a functional DNA recombination system involving the host recA gene.
D001426:Bacterial Proteins / Q000528:radiation effects*; D004279:DNA, Viral / Q000096:biosynthesis; D005796:Genes; D005809:Genes, Regulator; D009154:Mutation; D011830:Radiation Effects; D012483:Salmonella Phages / Q000254:growth & development / Q000378:metabolism / Q000528:radiation effects*; D012486:Salmonella typhimurium / Q000528:radiation effects*; D014466:Ultraviolet Rays; D014779:Virus Replication
D001426:Bacterial Proteins; D004279:DNA, Viral