title: Studies on the overproduction of dihydrofolate reductase by variant hamster cells in culture.
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D006224:Cricetinae; D004351:Drug Resistance; D004591:Electrophoresis, Polyacrylamide Gel; D005492:Folic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D005493:Folic Acid Antagonists; D005796:Genes; D007700:Kinetics; D008727:Methotrexate / Q000494:pharmacology; D008967:Molecular Biology; D012335:RNA, Ribosomal; D013762:Tetrahydrofolate Dehydrogenase / Q000096:biosynthesis*
chemical_list: D005493:Folic Acid Antagonists; D012335:RNA, Ribosomal; D005492:Folic Acid; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate