title: Multidrug chemotherapy in primary treatment of osteosarcoma. An editorial commentary.
mesh_terms: D000671:Amputation, Surgical; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004317:Doxorubicin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use; D009362:Neoplasm Metastasis; D012516:Osteosarcoma / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents; D004317:Doxorubicin; D008727:Methotrexate