title: Comparison of antinuclear antibody determinations in unselected sera by consumption test and immunofluorescence.
abstract: The correlation of the determination of antinuclear antibodies, as shown by consumption tests and immunofluorescence was investigated in a collective of 100 sera of patients suspected for SLE, collagenosis and rheumatoid arthritis, sent for routine screening investigation. The results of both methods correlated in 78% of sera, both results being either positive or negative. No correlation was observed in 22% of sera, one test being positive, the other negative. Statistical evaluation by the X2 test showed that both techniques did not differ statistically in their results. A correlation coefficient r=0,45 indicated furthermore that the results of both techniques correlated significantly. The percentage of positive results obtained with these and other methods is discussed.
mesh_terms: D000974:Antibodies, Antinuclear / Q000032:analysis*; D003095:Collagen Diseases / Q000175:diagnosis*; D005455:Fluorescent Antibody Technique; D006801:Humans; D012698:Serologic Tests
chemical_list: D000974:Antibodies, Antinuclear