Trimethoprim-sulfamethoxazole therapy of pulmonary melioidosis.
A 21-year-old-airman stationed in the Philippines presented with cavitary pulmonary melioidosis. When treated with trimethoprim-sulfamethoxazole, there was prompt resolution of his symptoms and the left upper lobe abscess cavity. It is suggested that this antimicrobial combination is an effective alternative regimen for pulmonary melioidosis.
D000328:Adult; D001431:Bacteriological Techniques; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D006801:Humans; D008169:Lung Abscess / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008297:Male; D008554:Melioidosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008826:Microbial Sensitivity Tests; D011859:Radiography; D013420:Sulfamethoxazole / Q000008:administration & dosage / Q000627:therapeutic use*; D014295:Trimethoprim / Q000008:administration & dosage / Q000627:therapeutic use*
D014295:Trimethoprim; D013420:Sulfamethoxazole