title: R factors derived from Shigella flexneri strains.
abstract: Of 2492 Shigelle flexneri strains isolated from dysenteric patients in Hungary in the years 1972-1974, 767 (30.8%) were resistant to 1-5 antibiotics. Resistance was due to R factors in 79.2% of the strains. Fertility inhibition experiments with F specific phages showed R factors to be fi+ in 12.9% and fi- and 87.1%. Of the antibiotic markers, the chloramphenicol-tetracycline resistance determinant was the most common (46.4%). Chloramphenicol resistance determinants were carried out by fi- R factors.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004405:Dysentery, Bacillary / Q000382:microbiology*; D006801:Humans; D006814:Hungary; D011815:R Factors; D012763:Shigella flexneri / Q000145:classification / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents