Mutagenicity of 5-nitroacenaphthene in salmonella.
5-Nitroacenaphthene was proved to be mutagenic on TA100 and TA98 of Salmonella typhimurium with or without metabolic activation by S-9 Mix. A possible metabolite, 5-hydroxyacenaphthene, carcinogenicity of which had not been observed, was non-mutagenic on TA100 and TA98, with or without metabolic activation.
D000073:Acenaphthenes / Q000494:pharmacology*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D009154:Mutation / Q000187:drug effects; D012486:Salmonella typhimurium / Q000187:drug effects*
D000073:Acenaphthenes; D004121:Dimethyl Sulfoxide