title: [Model experiments on the effect of IgM- and IgG-antibodies on the reactivity of Treponema pallidum hemagglutination (TPHA)-test].
abstract: Fractionated sera of patients in different stages of syphilis were examined comparatively with the TPHA-FTA(IgM)- and FTA(IgG)-test. It was shown that the TPHA-test proved to be convenient for early immunologic diagnosis of syphilis. The TPHA-test includes not only IgG anti-treponemal antibodies but also IgM antibodies. In the early stage of syphilis a reactive result of TPHA-test can be related exclusively on treponemal specific IgM antibodies.
mesh_terms: D000328:Adult; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D008297:Male; D008954:Models, Biological; D013587:Syphilis / Q000276:immunology; D013588:Syphilis Serodiagnosis / Q000379:methods*
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Modellversuche zur Wirkung von IgM- und IgG-Antikörpern auf die Reaktivität des Treponema-pallidum-Hämagglutinations(TPHA)-Tests