title: The blood groups, serum groups, red-cell isoenzymes and haemoglobins of the Sandawe and Nyaturu of Tanzania.
abstract: Blood specimens from members of the click-speaking Sandawe tribe of Tanzania and of the adjacent Bantu-speaking Nyaturu tribe have been tested for antigens of 11 blood group systems, for variants of 3 plasma-protein systems and 9 red-cell-enzyme systems, for haemoglobin variants. The results are tabulated and gene frequencies computed. For most systems, the frequencies in the two tribes are similar to one another and, in so far as data are available, similar to the neighbouring Bantu-speaking tribes. The principal genetic difference between the Sandawe and the Nyaturu is in their frequencies of haemoglobin S and of glucose-6-phosphate dehydrogenase deficiency, both of which characters are several times higher in the Nyaturu than in the Sandawe; both characters are protective against falciparum malaria, and this suggests that the Nyaturu have in the past been much more strongly exposed to this infection than the Sandawe.
mesh_terms: D044383:Black People; D001789:Blood Group Antigens; D004912:Erythrocytes / Q000201:enzymology*; D005787:Gene Frequency; D005955:Glucosephosphate Dehydrogenase Deficiency; D006451:Hemoglobin, Sickle; D006454:Hemoglobins; D006801:Humans; D007527:Isoenzymes; D008288:Malaria / Q000235:genetics; D010963:Plasmodium falciparum; D013636:Tanzania
chemical_list: D001789:Blood Group Antigens; D006451:Hemoglobin, Sickle; D006454:Hemoglobins; D007527:Isoenzymes