title: Repression of alkaline phosphatase in Salmonella typhimurium carrying a phoA+ phoR- episome from Escherichia coli.
abstract: Salmonella typhimurium does not produce alkaline phosphatase (nor beta-galactosidase). Nevertheless, it has the function of the phoR+ regulatory gene but lacks the function of the lacI+ regulatory gene. Several periplasmic proteins are derepressed when cells of S. typhimurium are starved for inorganic phosphate. The role of phoR is discussed.
mesh_terms: D000469:Alkaline Phosphatase / Q000096:biosynthesis*; D004794:Enzyme Repression; D004926:Escherichia coli; D005111:Extrachromosomal Inheritance; D005696:Galactosidases / Q000096:biosynthesis; D005809:Genes, Regulator; D010957:Plasmids; D012486:Salmonella typhimurium / Q000201:enzymology*
chemical_list: D000469:Alkaline Phosphatase; D005696:Galactosidases