[Role of circulating antibodies and cellular factors in the pathogenesis of Staphylococcus induced rejection of skin autotransplants].
It was found that rejection of the skin autotransplant in the staphylococcus-sensitized animals was accompanied by regular changes in the titres of auto- and staphylococcus antibodies indirectly pointing to the antibody fixation on the rejecting transplant or to their neutralization with the antigens of the perishing skin transplant. In experiments with passive reproduction of the state of rejection in the intact syngenous recipients it was shown that the decisive role in this process was played by the cell factors, but not by the blood serum. The mentioned facts pointed to the role played by allergy of delayed type in the pathogenesis of rejection of skin autotransplants induced with staphylococcus.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D006084:Graft Rejection / Q000276:immunology*; D007111:Immunity, Cellular; D051379:Mice; D016038:Skin Transplantation; D013210:Staphylococcus / Q000276:immunology*; D014182:Transplantation, Autologous
D000907:Antibodies, Bacterial
O roli tsirkuliruiushchikh antitel i kletochnykh faktorov v patogeneze indutsirovannogo stafilokokkom ottorzheniia autotransplantatov kozhi