title: Dead or alive: the problem of in vitro tissue mechanics.
abstract: Extensive studies have been made of the biomechanical properties of tissues in vitro. The majority of experiments demonstrate a "preconditioning" effect. This effect is associated with the differences between in vivo and in vitro conditions. Failure to utilize initial or isochronal data may lead to erroneous conclusions. Objective criteria would permit comparison between experiments.
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001842:Bone and Bones / Q000502:physiology; D002468:Cell Physiological Phenomena; D006652:Histological Techniques; D066298:In Vitro Techniques; D051381:Rats; D012107:Research Design; D013710:Tendons / Q000502:physiology / Q000601:surgery; D014022:Tissue Survival