[Effect of polyvinylpyridine-N-oxide on the state of phagocyte-lymphoid elements in aseptic inflammation].
Cytochemical study of NAD-diaphorase and acid phosphatase (mitochondria and lysosomes markers) in the cells of the abdominal cavity exudate with aseptic inflammation and additional action of polyvinylpyridne-N-oxide with molecular weight in the range of from 2000 to 150 000 formed a background for demonstrating the possibility of stabilizing by means of the latter compound of mitochondrial and lysosomal membranes of macrophages, neutrophils and lymphocytes. The most pronounced stabilizing effect is produced by polyvinylpyridine-N-oxide with a molecular weight of 50 000 with its intramuscular introduction in a dose of 100 mg/kg.
D000135:Acid Phosphatase / Q000032:analysis; D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D002452:Cell Count; D002462:Cell Membrane / Q000187:drug effects; D008058:Dihydrolipoamide Dehydrogenase / Q000032:analysis; D005549:Foreign-Body Reaction / Q000473:pathology; D007962:Leukocytes / Q000187:drug effects*; D008214:Lymphocytes / Q000201:enzymology; D008247:Lysosomes / Q000187:drug effects; D008264:Macrophages / Q000187:drug effects* / Q000201:enzymology; D051379:Mice; D008928:Mitochondria / Q000187:drug effects; D009504:Neutrophils / Q000201:enzymology; D010537:Peritoneum / Q000293:injuries; D011144:Polyvinylpyridine N-Oxide / Q000494:pharmacology*; D011145:Polyvinyls / Q000494:pharmacology*
D011145:Polyvinyls; D011144:Polyvinylpyridine N-Oxide; D008058:Dihydrolipoamide Dehydrogenase; D000135:Acid Phosphatase
Vliianie polivinilpiridin-N-oksida na sostoianie fagotsitarno-limfoidnykh elementov pri asepticheskom vospalenii.