title: [FSH, LH and testosterone evaluation in healthy males from pre-puberty to senile age. Study in basic conditions and after stimulation with Gn-RH].
abstract: The secretion values of the two seric gonadotropins and of plasmatic Testosterone have been estimated in a casuistry of normal males, 114 subjects, subdivided in groups of 8 to 95 years of age. Our investigation allowed to compare hormonal levels in the different ages; in particular, the pattern in senescence appeared greatly interesting. In one part of this casuistry, we have estimated the response to the intravenous administration of Gn-RH. The test showed a positive gonadotropic response in all ages, with some differences between FSH and LH, and induced no significant change in testosterone secretion. Among the results which have been obtained, it appears that physiologic hypogonadism of the elderly is a primary phenomenon, not hypophysodependent.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone; D006801:Humans; D007275:Injections, Intravenous; D007986:Luteinizing Hormone / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D010902:Pituitary Gland / Q000502:physiology; D013268:Stimulation, Chemical; D013739:Testosterone / Q000378:metabolism*
chemical_list: D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
vernacular_title: Valutazione di FSH, LH, testosterone nell'uomo sano, dall'eta prepubere alla senile. Studio in condizioni di base e dopo stimolo con Gn-RH