Biological mediators of inflammation im middle ear effusions.
Four biological mediators of inflammation have been found in middle ear effusions from patients with otitis media with effusion. They are chemotactic factor(s), macrophage inhibition factor(s), activated complement and prostaglandins. The potential role of these mediators has been discussed in relation to their potential for maintaining inflammation in the middle ear cleft after Eustachian tube dysfunction.
D000818:Animals; D002633:Chemotaxis; D003165:Complement System Proteins / Q000502:physiology*; D004432:Ear, Middle / Q000276:immunology; D005122:Exudates and Transudates / Q000276:immunology; D006168:Guinea Pigs; D006801:Humans; D008263:Macrophage Migration-Inhibitory Factors / Q000502:physiology*; D008264:Macrophages / Q000276:immunology; D009504:Neutrophils / Q000276:immunology; D010033:Otitis Media / Q000276:immunology / Q000503:physiopathology*; D011453:Prostaglandins / Q000502:physiology*
D008263:Macrophage Migration-Inhibitory Factors; D011453:Prostaglandins; D003165:Complement System Proteins