Preformed autologous ossicles. Experimental studies.
On the basis of earlier experimental investigations concerning autogenous bone transplants a project is going on with the view to have a patient to create his own bone graft suitable for being used in reconstructive surgery of the middle ear. This theory was tested in 6 rabbits and 6 dogs where a titanium form was installed in the proximal tibial metaphysis. The healing time was 6-8 months. After extraction histologic examination of the facsimile showed that it consisted of an outer form-giving thin layer ocal bone and a system of spongious bone surrounded by marrow with haemopoetic cells. Microradiologic analyses revealed a well mineralized trabecular bone tissue. By means of microangiography a microvascular architecture with a mature appearance could be demonstrated.
D000818:Animals; D016025:Bone Transplantation; D004285:Dogs; D004429:Ear Ossicles / Q000098:blood supply / Q000601:surgery*; D008722:Methods; D014025:Titanium; D014182:Transplantation, Autologous
D014025:Titanium