Clofazimine in the treatment of dapsone resistant leprosy.
Dapsone resistant patients treated with clofazimine 100 mg daily show a consistent response to treatment. Concern is expressed regarding the prolonged persistence of viable organisms during treatment, with the attendant risk of further resistance developing. The importance of prevention of this problem is discussed.
D002991:Clofazimine / Q000009:adverse effects / Q000627:therapeutic use*; D003622:Dapsone / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D006801:Humans; D007918:Leprosy / Q000188:drug therapy* / Q000382:microbiology; D009166:Mycobacterium leprae / Q000187:drug effects
D003622:Dapsone; D002991:Clofazimine