Identification of a genetic locus affecting chromosome stabiltiy and cellular survival in a dnaB mutant.
A mutation has been identified in an Escherichia coli K-12 strain carrying dnaB42. This mutation potentiates both deoxyribonucleic acid degradation and cell death at nonpermissive temperatures. It is located 2 min away from dnaB between malB and metA.
D002874:Chromosome Mapping; D003227:Conjugation, Genetic; D004269:DNA, Bacterial / Q000378:metabolism*; D004926:Escherichia coli / Q000378:metabolism*; D005796:Genes; D008040:Genetic Linkage; D009154:Mutation; D013696:Temperature; D014161:Transduction, Genetic
D004269:DNA, Bacterial