title: Metabolic activation: biochemical basis for many drug-induced liver injuries.
mesh_terms: D000082:Acetaminophen / Q000009:adverse effects / Q000378:metabolism; D000818:Animals; D001665:Binding Sites; D002273:Carcinogens; D056486:Chemical and Drug Induced Liver Injury; D004342:Drug Hypersensitivity / Q000209:etiology; D064420:Drug-Related Side Effects and Adverse Reactions; D005665:Furosemide / Q000009:adverse effects / Q000378:metabolism; D006801:Humans; D006834:Hydrazines / Q000009:adverse effects / Q000378:metabolism; D007538:Isoniazid / Q000009:adverse effects / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008750:Methyldopa / Q000009:adverse effects / Q000378:metabolism; D009336:Necrosis / Q000139:chemically induced; D004364:Pharmaceutical Preparations / Q000378:metabolism; D010615:Phenacetin / Q000009:adverse effects / Q000378:metabolism; D013876:Thiophenes / Q000009:adverse effects / Q000378:metabolism
chemical_list: D002273:Carcinogens; D006834:Hydrazines; D004364:Pharmaceutical Preparations; D013876:Thiophenes; D000082:Acetaminophen; D008750:Methyldopa; D005665:Furosemide; D010615:Phenacetin; D007538:Isoniazid