Immunosuppressive effect in mycobacterial adjuvant emulsions of mineral oils containing low molecular weight hydrocarbons.
Bayol F preparations from different commercial sources were incorporated into water-in-oil emulsions containing mycobacterial fractions and a protein antigen. It was found that an adjuvant effect was obtained with some mineral oils and a toxic immunosuppressive effect with others.
D000276:Adjuvants, Immunologic; D000818:Animals; D000941:Antigens; D002849:Chromatography, Gas; D006168:Guinea Pigs; D006838:Hydrocarbons / Q000032:analysis; D006968:Hypersensitivity, Delayed; D007165:Immunosuppression Therapy; D008899:Mineral Oil / Q000494:pharmacology*; D009163:Mycobacterium bovis / Q000276:immunology
D000276:Adjuvants, Immunologic; D000941:Antigens; D006838:Hydrocarbons; D008899:Mineral Oil