The centrineurogenic etiology of the respiratory distress syndrome: protection by unilateral chronic pulmonary denervation in hemorrhagic shock.
Anemic beagles were subjected to 40 mm Hg hemorrhagic shock for 2 hours, which uniformly induced the pulmonary lesions of the "respiratory distress syndrome" (RDS) bilaterally in all six controls. For six subjects with complete denervation of the left lung 2 months previously, the shock regimen induced the lesions in the normally innervated right lungs; all reimplanted, denervated left lungs remained anatomically intact. This is presented as additional evidence for a centrineurogenic etiology for RDS.
D000818:Animals; D003714:Denervation; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000294:innervation / Q000473:pathology; D016040:Lung Transplantation; D008297:Male; D012127:Respiratory Distress Syndrome, Newborn / Q000150:complications / Q000209:etiology* / Q000473:pathology; D012771:Shock, Hemorrhagic / Q000150:complications* / Q000473:pathology