[Certain metabolic and vascular changes in the relatives of patients with diabetes mellitus].
On the basis of instrumental and biochemical study of 186 relatives suffering from diabetes mellitus it was revealed that the diabetic type of sugar curve was encountered in 17.2% of cases, doubltful--in 15.6%; at the same time there was revealed an increase in the immunoreactive insulin level both on fasting stomach and after the glucose load, and a distrubance of fat-lipoid metabolism. Functional changes in the vessels of different calibre independent of the GTT character, accompanied by a reduction of vascular permeability and tissue circulation were revealed in some of the persons examined.
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D001808:Blood Vessels / Q000503:physiopathology; D003920:Diabetes Mellitus / Q000235:genetics*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood; D007515:Islets of Langerhans / Q000503:physiopathology; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D011236:Prediabetic State / Q000175:diagnosis* / Q000503:physiopathology
D001786:Blood Glucose; D007328:Insulin; D008055:Lipids
Nekotorye metabolicheskie i sosudistye izmeneniia u rodstvennikov bol'nykh sakharnym diabetom