Fungal infections after renal transplantation.
Fungal infections occurred in 3 of 22 renal transplants (13.6%). Two patients developed rhinocerebral phycomycosis, and Rhizopus arrhizus was isolated from cultures of the nasal conchae. Both patients were treated with systemic amphotericin B. Three-and-a-half months after transplantation the third patient developed an acute ureteral obstruction secondary to infection with Aspergillus nidulans; this necessitated removal of the graft. There was no immediate mortality associated with these fungal infections but there was immediate loss of the grafts in the two patients.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001230:Aspergillus / Q000302:isolation & purification; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D009181:Mycoses / Q000150:complications / Q000188:drug therapy / Q000209:etiology*; D012233:Rhizopus / Q000302:isolation & purification; D014184:Transplantation, Homologous; D014517:Ureteral Obstruction / Q000209:etiology
D000666:Amphotericin B