title: [Multiple sclerosis. Etiopathogenetic review].
abstract: This is a synthetic report about multiple sclerosis: there is described the neuropathology (by optic and electronic microscopy) of this disease, the changes in the protein metabolism, above all in basic protein content, in lipids, in enzymes of the plaques and of the apparently normal white and gray matter. There are afterwords described the relationship between viruses and multiple sclerosis, the probable action mechanism of the virus-determined demyelination, and the changes of the immunitary system (increase of gamma-globulins, serum myelotoxicity, lymphocitary changes).
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D001921:Brain / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D008213:Lymphocyte Activation; D009103:Multiple Sclerosis / Q000209:etiology* / Q000276:immunology / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000378:metabolism; D011134:Polysaccharides / Q000378:metabolism
chemical_list: D000914:Antibodies, Viral; D009419:Nerve Tissue Proteins; D011134:Polysaccharides
vernacular_title: La sclerosi a placche. Aggiornamento etiopatogenico