A new look at the serology of treponemal disease.
The serology of treponemal disease has become simpler and more rational in recent years, mainly as a result of the widespread adoption of specific antibody tests and the use of monospecific fluorescent antibody procedures which give information about the immunoglobulin class of antibodies. A set of tests which has proved particularly useful in routine diagnosis is the following: quantitative TPHA test, quantitative VDRL test, and monospecific (IgG and IgM) FTA-ABS tests. This combination is especially valuable in the assessment of new patients with positive results to serological tests and in the management of patients with treated syphilis.
D000907:Antibodies, Bacterial / Q000145:classification; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013588:Syphilis Serodiagnosis; D013590:Syphilis, Congenital / Q000175:diagnosis; D014211:Treponemal Infections / Q000175:diagnosis* / Q000276:immunology
D000907:Antibodies, Bacterial