Role of heparin therapy in the outcome of adult hemolytic uremic syndrome.
Intravenous heparin therapy was associated with complete recovery of renal function in a young woman who developed adult hemolytic uremic syndrome while taking oral contraceptive agents. No controlled study is yet available but a review of an additional 36 reported patients who fulfill adequate criteria for the diagnosis of adult hemolytic uremic syndrome suggests that consideration should be given to a trial of heparin therapy in patients with this syndrome in whom renal biopsy shows recoverable glomeruli in the presence of persistent severe impairment of renal function.
D000293:Adolescent; D003280:Contraceptives, Oral, Synthetic / Q000009:adverse effects; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans
D003280:Contraceptives, Oral, Synthetic; D006493:Heparin