[Gastric tolerance of different preparations of acetylsalicylic acid in postoperative prevention of thrombo-embolism (author's transl)].
The necessity for thrombosis-prophylaxis is indisputable. The evaluation of our patients over a period of 2 years revealed results compatible with other authors. Due to its thrombocyte desaggregating action, acetyl-salicylic acid was found to have a definite effect on the thrombophilia by inhibiting the thrombocyte adhesiveness in a beginning thrombosis. It was shown that acetylsalicylic acid in combination with glycocoll is apparently superior to microencapsulated acetylic acid in terms of gastric tolerance. In a small number of patients the therapeutic efficiency was investigated and according to the platelets agglutination test, verified. Further investigations are planned in a major series of patients where acetylsalicylic acid with glycocoll was administered in respect to the treatment of rheumatic fever.
D001241:Aspirin / Q000009:adverse effects* / Q000494:pharmacology; D001682:Biological Availability; D002986:Clinical Trials as Topic; D003692:Delayed-Action Preparations; D004338:Drug Combinations; D004339:Drug Compounding; D004361:Drug Tolerance; D005753:Gastric Mucosa / Q000187:drug effects; D005998:Glycine / Q000627:therapeutic use; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects; D011182:Postoperative Care; D012189:Retrospective Studies; D013923:Thromboembolism / Q000517:prevention & control*
D003692:Delayed-Action Preparations; D004338:Drug Combinations; D001241:Aspirin; D005998:Glycine
Verträglichkeit verschiedener Acetylsalicylsäurepräparate in der Thromboseprophylaxe