A double-blind study comparing Daktacort, miconazole and hydrocortisone in inflammatory skin infections.
In a 4-week double-blind trial, Daktacort cream was compared with each of its constituents (i.e. miconazole 2% and hydrocortisone 1%) in a total of 63 patients (aged 12-60 years) with inflamed skin infections of bacterial or mycotic origin. Daktacort treatment induced a significant improvement of all symptoms within 1 week and was superior to both miconazole and hydrocortisone in suppressing the inflammation. This tendency persisted throughout the trial but at the end miconazole treatment proved also superior to hydrocortisone.
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002648:Child; D002986:Clinical Trials as Topic; D004338:Drug Combinations; D005260:Female; D006801:Humans; D006854:Hydrocortisone; D007093:Imidazoles / Q000627:therapeutic use*; D008297:Male; D008825:Miconazole / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D012874:Skin Diseases, Infectious / Q000188:drug therapy* / Q000473:pathology
D000893:Anti-Inflammatory Agents; D004338:Drug Combinations; D007093:Imidazoles; D008825:Miconazole; D006854:Hydrocortisone