Identification of the D1-cell as the source of human pancreatic polypeptide (HPP).
Immunoperoxidase positive HPP-producing cells have been examined ultrastructurally using the serial semithin-thin section technique. The features of the HPP cells were found to be identical with those of the previously described D1-cell. The D1-cells are scattered throughout the exocrine parenchyma and occur to a minor extent in the islets.
D002462:Cell Membrane / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D006801:Humans; D007124:Immunoenzyme Techniques; D007515:Islets of Langerhans / Q000648:ultrastructure*; D008854:Microscopy, Electron; D010179:Pancreas / Q000378:metabolism* / Q000648:ultrastructure; D010455:Peptides / Q000378:metabolism*
D010455:Peptides