Morphological changes in indefinitely surviving enhanced ectopic rat cardiac allografts.
The histological changes of ectopic cardiac allografts in rats have been studied. These consisted of (a) a diffuse chronic inflammatory cell infiltrate of the myocardial interstitium accompanied by variable degrees of fibrosis (b) variable degrees of intimal hyperplasia of the coronary arteries with segmental disruption of the internal elastic lamina.
D000818:Animals; D003331:Coronary Vessels / Q000473:pathology*; D004699:Endocardium / Q000473:pathology*; D005260:Female; D006084:Graft Rejection / Q000473:pathology*; D016027:Heart Transplantation; D006965:Hyperplasia; D008297:Male; D009206:Myocardium / Q000473:pathology*; D051381:Rats; D013997:Time Factors; D014184:Transplantation, Homologous