title: Spontaneous regression of breast cancer.
abstract: The dramatic but rare regression of a verified case of breast cancer in the absence of adequate, accepted, or conventional treatment has been observed and documented by clinicians over the course of many years. In my practice limited to diseases of the breast, over the past 25 years I have observed 12 patients with a unique and unusual clinical course valid enough to be regarded as spontaneous regression of breast cancer. These 12 patients, with clinically confirmed breast cancer, had temporary arrest or partial remission of their disease in the absence of complete or adequate treatment. In most of these cases, spontaneous regression could not be equated ultimately with permanent cure. Three of these case histories are summarized, and patient characteristics of pertinent clinical interest in the remaining case histories are presented and discussed. Despite widespread doubt and skepticism, there is ample clinical evidence to confirm the fact that spontaneous regression of breast cancer is a rare phenomenon but is real and does occur.
mesh_terms: D000328:Adult; D000818:Animals; D001943:Breast Neoplasms / Q000150:complications / Q000266:history / Q000473:pathology*; D002369:Castration; D002417:Cattle; D004967:Estrogens / Q000378:metabolism; D005260:Female; D006042:Goiter / Q000150:complications; D012739:Gonadal Steroid Hormones / Q000627:therapeutic use; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D008297:Male; D008512:Medicine in the Arts; D008593:Menopause; D008598:Menstruation; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009365:Neoplasm Regression, Spontaneous; D010053:Ovary / Q000378:metabolism; D012068:Religion and Medicine
chemical_list: D004967:Estrogens; D012739:Gonadal Steroid Hormones