[Plexiglas (PMMA) in the anterior chamber. An experimental study on biological compatibility].
For six months the anterior chambers of rabbits were examined at regular intervals with the slit-lamp photograph. The reactions of iris, aqueous, and cornea were observed after implanting one PMMA-disc (0.25 mm thickness and 1.5 mm diameter) through a lancet incision. At the place where the disc touched the iris one could see during the half year period hyperaemia iridis, ciliary injection, atrophia iridis, and foreign-substance-granuloma of the iris with partial adhesion of the iris wrinkles. The cause for these reactions is a toxin in the PMMA. Mechanical irritation and plastic alteration could be excluded by the experimental method.
D000818:Animals; D000867:Anterior Chamber; D005129:Eye Foreign Bodies; D005549:Foreign-Body Reaction; D007498:Iris / Q000601:surgery; D007909:Lenses / Q000009:adverse effects*; D010969:Plastics / Q000009:adverse effects* / Q000633:toxicity; D019736:Prostheses and Implants / Q000009:adverse effects*; D011817:Rabbits; D014603:Uveal Diseases / Q000139:chemically induced
D010969:Plastics
Plexiglas (PMMA) in der Vorderkammer. Eine experimentelle studie zur biologischen Verträglichkeit