title: Comparative study of R1-specific chromosomal transfer in Escherichia coli K-12 and salmonella typhimurium LT2.
abstract: High-frequency transfer of the chromosomal trp region by R1 observed in Escherichia coli (Pearce and Meynell, 1968) also occurs in Salmonella typhimurium. The reaction is recA independent in both species. The origin of transfer lies within a segment of the chromosome that is inverted in S. typhimurium relative to E. coli, and thus transfer occurs in a different direction in the two species. The character of R1 that is responsible, known as Tfa+, may be lost without affecting other properties of the R factor such as its own transfer.
mesh_terms: D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D003227:Conjugation, Genetic; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism; D005796:Genes; D009154:Mutation; D011815:R Factors; D011995:Recombination, Genetic; D012486:Salmonella typhimurium / Q000187:drug effects / Q000378:metabolism; D014170:Transformation, Genetic; D014364:Tryptophan / Q000096:biosynthesis
chemical_list: D014364:Tryptophan