Failure of trehalose-6,6'-dimycolate (P3 or cord factor) to enhance endotoxin lethality in mice.
The increased endotoxin lethality in mice pretreated with BCG was not observed in mice pretreated with trehalose-6,6'-dimycolate instead of BCG.
D000818:Animals; D001500:BCG Vaccine; D003311:Cord Factors / Q000494:pharmacology*; D004731:Endotoxins / Q000633:toxicity*; D006017:Glycolipids / Q000494:pharmacology*; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D009163:Mycobacterium bovis / Q000472:pathogenicity
D001500:BCG Vaccine; D003311:Cord Factors; D004731:Endotoxins; D006017:Glycolipids