[Present state in synchronization therapy of malignant tumors and acute leukemias (author's transl)].
Chemotherapy of malignant tumors can be made more effective by synchronization of the cell cycle. Synchronization therapy consists of a synchronizing step (phase I), an interval and a cytocidal step (phase II). Some regimens till now approved in clinical treatment are presented. The results are found to be encouraging. In all schedules three effects work together namely synchronization recruitment, summation.
D002455:Cell Division / Q000187:drug effects*; D003584:Cytological Techniques; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D006801:Humans; D007938:Leukemia / Q000188:drug therapy*; D009369:Neoplasms / Q000188:drug therapy*; D013997:Time Factors
Derzeitiger Stand der Synchronisationstherapie von malignen Tumoren und akuten Leukämien