[Genetic-biochemical study of acid phosphatases from Saccharomyces cerevisiae yeasts. IV. Genetic control of acid phosphatase II activity].
Genetic control of exocellular acid phosphatase of yeast Saccharomyces cerevisiae (acph 2) is studied. 64 mutants with the impaired activity of acid phosphatase have been obtained by UV-irradiation. All the mutations have been distributed among 4 genes: ACP1, ACP2, ACP3, ACP4 using functional and recombinational tests for allelism. It is shown that mutations in genes ACP1--ACP3 are recessive, but in the gene ACP4--dominant. The gene ACP4 is found to be located 0.41+/-0.064 in strains from centromere and to have no linkage with ACP1. Possible functions of genes studied are under discussion.
D000135:Acid Phosphatase / Q000378:metabolism*; D009154:Mutation; D011831:Radiation Genetics; D012441:Saccharomyces cerevisiae / Q000201:enzymology* / Q000528:radiation effects; D014466:Ultraviolet Rays
D000135:Acid Phosphatase
Genetiko-biokhimicheskoe izuchenie kislykh fosfataz drozhzheĭ Saccharomyces cerevisiae. Soobshchenie IV. Geneticheskiĭ kontrol' aktivnosti kisloĭ fosfatazy II