title: [Cortico-striate spinal degeneration. Report of a case with pathological and clinical findings suggestive of Creutzfeldt-Jakob disease].
abstract: A case suggestive of Creutzfeldt-Jakob disease in an adult with widespread lesions of the cerebral cortex, striatum and the spinal cord is reported. Anatomopathological studies showed neuronal degeneration, astrocytic proliferation, intense lymphoplasmocytic activity and slight spongiform degeneration. This inflammatory lymphocytic infiltration corroborates the hypothesis of viral etiology of this disease.
mesh_terms: D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D013116:Spinal Cord / Q000473:pathology
vernacular_title: Degeneração cortico-estriato-medular. Relato de um caso com achados clinicos e patologicos sugestivos de doença de Creutzfeldt-Jakob