title: [Characteristics of the basic parameters of killed influenza vaccine purified and concentrated on sodium borsilicate glass].
abstract: The main parameters (reactogenicity, harmlessness, immunogenicity and prophylactic efficacy) of experimental batches of the inactivated influenza vaccine A, purified and concentrated on sodium-boron-silicate glass, were studied in strictly controlled epidemiological trial. In single subcutaneous injection in a dose of 0.5 ml (5120 hemagglutinating units) of the vaccine it was characterized by a moderate reactogenicity, marked antigenicity and prophylactic, efficacy.
mesh_terms: D001896:Boron Compounds; D002986:Clinical Trials as Topic; D005898:Glass; D006801:Humans; D007252:Influenza Vaccines / Q000009:adverse effects / Q000302:isolation & purification*; D007251:Influenza, Human / Q000517:prevention & control*; D008722:Methods; D012824:Silicic Acid; D012964:Sodium; D014611:Vaccination / Q000009:adverse effects
chemical_list: D001896:Boron Compounds; D007252:Influenza Vaccines; D012824:Silicic Acid; D012964:Sodium
vernacular_title: Kharakteristike osnovnykh parametrov ubitoĭ grippoznoĭ vaktsiny, ochishchennoĭ i kontsentrirovannoĭ na natriĭborsilikatnom stekle