title: Gene manipulation.
mesh_terms: D004269:DNA, Bacterial / Q000378:metabolism; D004352:Drug Resistance, Microbial; D004720:Endonucleases / Q000378:metabolism; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism; D005818:Genetic Engineering; D010957:Plasmids; D011815:R Factors; D012333:RNA, Messenger; D011995:Recombination, Genetic; D013754:Tetracyclines / Q000494:pharmacology; D014170:Transformation, Genetic
chemical_list: D004269:DNA, Bacterial; D012333:RNA, Messenger; D013754:Tetracyclines; D004720:Endonucleases