Phenotypic instability in a tif-1 mutant of Escherichia coli. II. Recessiveness of the tif-1 mutation.
Merodiploids of the type tif-1/F'tif+, constructed in E. coli K12 strain T44(lambda), show that the tif-1 mutation is recessive with respect to induction of phage lambda and thermolability. An additional manifestation of tif-1 expression is increased tolerance to low levels of streptomycin (SM) and chloramphenicol (CM) and this, too, is abolished in the merodiploids.
D002701:Chloramphenicol / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism*; D005808:Genes, Recessive; D009154:Mutation; D010641:Phenotype; D013307:Streptomycin / Q000494:pharmacology
D002701:Chloramphenicol; D013307:Streptomycin