Visualization of stimulated nerve endings by preferential calcium accumulation of mitochondria.
Calcium was detected by X-ray microanalysis in the mitochondria of electrically stimulated nerve endings. The phenomenon described here offers a simple means for identifying the stimulated nerve endings in the electron microscope and appears to be a promising new method for following spontaneous and drug-stimulated translocation of calcium in relation to the regulation of neurotransmitter release.
D000818:Animals; D002118:Calcium / Q000032:analysis*; D002415:Cats; D003584:Cytological Techniques; D003712:Dendrites / Q000648:ultrastructure; D004558:Electric Stimulation; D005725:Ganglia, Autonomic / Q000648:ultrastructure*; D008928:Mitochondria / Q000032:analysis* / Q000648:ultrastructure; D009411:Nerve Endings / Q000648:ultrastructure*; D012583:Schwann Cells / Q000648:ultrastructure; D013569:Synapses / Q000648:ultrastructure
D002118:Calcium