title: Clinical manifestations of cancer of the colon and rectum.
abstract: Cancer of the large bowel produces a background of abdominal pain, bleeding, and altered bowel function. The anatomy, physiology, and pathology of the bowel modify this basic pattern to emphasize certain features and minimize others, so that disease in different locations produces different patterns.
mesh_terms: D000005:Abdomen; D000740:Anemia / Q000209:etiology; D000818:Animals; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000473:pathology; D003248:Constipation / Q000209:etiology; D003672:Defecation; D003967:Diarrhea / Q000209:etiology; D005243:Feces; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D010146:Pain / Q000209:etiology; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000473:pathology