Iron absorption from hemiglobin (stable oxidation product of hemoglobin) in relation to the dose in subjects with normal and depleted iron stores.
The dose relationship of hemiglobin iron absorption has been investigated in subjects with normal and depleted iron stores and was found to fit a linear regression in a bilogarithmic presentation of hemiglobin iron dose and iron absorption. Identical regression coefficients but different intercepts of regression were estimated for subjects with normal and depleted iron stores indicating a constant proportional increase of hemiglobin iron absorption in subjects with depleted iron stores in the full dose range of 0.10-50 mg hemiglobin iron.
D000284:Administration, Oral; D000818:Animals; D004305:Dose-Response Relationship, Drug; D006454:Hemoglobins / Q000008:administration & dosage / Q000378:metabolism*; D006801:Humans; D007408:Intestinal Absorption; D007501:Iron / Q000097:blood*; D000090463:Iron Deficiencies; D007504:Iron Radioisotopes; D012044:Regression Analysis; D013552:Swine
D006454:Hemoglobins; D007504:Iron Radioisotopes; D007501:Iron