Reaction of the urinary tract to polypropylene sutures.
Cystotomies were performed on 99 mature guinea pigs and closed with polypropylene sutures. The bladders were removed at intervals from day 4 through day 144 postoperatively. They were studied with both light and electron microscopy. A localized mild, acute, inflammatory reaction was noted transitorily; it subsided between the 7th and 14th day. Three calculi were formed, a result which compares favorably with studies of other sutures. Results indicate that the suture may have a place in urologic surgery, but further studies are necessary before clinical use.
D000818:Animals; D005549:Foreign-Body Reaction / Q000209:etiology; D006168:Guinea Pigs; D010969:Plastics / Q000494:pharmacology*; D011126:Polypropylenes / Q000494:pharmacology*; D013537:Sutures; D001743:Urinary Bladder / Q000187:drug effects / Q000473:pathology* / Q000601:surgery; D014945:Wound Healing / Q000187:drug effects
D010969:Plastics; D011126:Polypropylenes