title: [Dichlorphenamide treatment in acute glaucoma (author's transl)].
abstract: Dichlorphenamide as well as Diamox lowers intraocular pressure. For adequate treatment of acute glaucoma only 20% of commonly used Diamoxdosis is requested to reach comparable pressure release two hours later. After one hour control intraocular pressure of 60% from patients with Dichlorphenamide treatment was found below 40 mm Hg since in Diamoxgroup there were only 30% below 40 mm Hg. Different effects of Dichlorphenamide and Diamox after one hour use is demonstrated in respect of serum electrolytes and base excess as well. Essential side effects after a single dosis of 200 mg Dichlorphenamide or in combination with Diamox for acute glaucoma treatment could not be observed.
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use; D000136:Acid-Base Equilibrium / Q000187:drug effects; D000208:Acute Disease; D002986:Clinical Trials as Topic; D004005:Dichlorphenamide / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood
chemical_list: D012964:Sodium; D000086:Acetazolamide; D011188:Potassium; D004005:Dichlorphenamide
vernacular_title: Die Wirkung von Dichlorphenamid bei der Behandlung des akuten Glaukomanfalls