title: [Controlled clinical trial of parsalmide].
abstract: A double-blind, between-patients comparison between parsalmide (a new drug) and phenylbutazone in 55 patients with postraumatic joint and muscle pain showed that the two compounds possessed about the same anti-inflammatory and analgesic activity, though parsalmide gave greater relief of pain and local swelling. Tolerance was excellent for both drugs. Slight gastric disturbances noted in 2 subjects with both compounds were easily corrected by symptomatic management.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D001549:Benzamides / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D006801:Humans; D007592:Joint Diseases / Q000188:drug therapy*; D007596:Joints / Q000293:injuries; D008297:Male; D008875:Middle Aged; D010653:Phenylbutazone / Q000627:therapeutic use
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001549:Benzamides; D010653:Phenylbutazone
vernacular_title: Sperimentazione clinica controllata di parsalmide