Clinicopathological spectrum of late postpartum renal failure; two contrasting cases.
The clinical and renal biopsy findings from two patients in whom renal functional abnormalities developed in the late postpartum period are described. Both biopsies showed fibrin deposition in the renal vasculature, in one case marked and in the other mild. The patient with the more severely damaged kidney subsequently died, and the other is alive but with evidence of slowly progressing renal damage. The clinicopathological spectrum and pathogenesis of late postpartum renal failure are discussed.
D058186:Acute Kidney Injury / Q000473:pathology* / Q000628:therapy; D000818:Animals; D001706:Biopsy; D001777:Blood Coagulation / Q000187:drug effects; D004211:Disseminated Intravascular Coagulation / Q000150:complications; D004876:Ergot Alkaloids / Q000009:adverse effects; D005260:Female; D005337:Fibrin / Q000032:analysis; D005455:Fluorescent Antibody Technique; D006463:Hemolytic-Uremic Syndrome / Q000209:etiology / Q000473:pathology; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007511:Ischemia / Q000473:pathology; D007668:Kidney / Q000098:blood supply; D007678:Kidney Glomerulus / Q000473:pathology / Q000648:ultrastructure; D011247:Pregnancy; D011644:Puerperal Disorders / Q000473:pathology*
D004876:Ergot Alkaloids; D005337:Fibrin