title: Attempts to induce hepatic uridine diphosphate glucuronyl transferase in genetically deficient Gunn rats by grafting of normal liver tissue.
abstract: Liver from normal Wistar rats was grafted into the liver of homozygous Gunn rats which are deficient in UDP glucuronyl transferase (UDPGT) (bilirubin) activity. After 3 months, UDPGT activity (bilirubin) remained absent in microsomal suspensions of liver from recipient rats and no bilirubin glucuronide was detected in their bile.
mesh_terms: D000818:Animals; D001663:Bilirubin / Q000097:blood / Q000378:metabolism; D006720:Homozygote; D008099:Liver / Q000201:enzymology*; D016031:Liver Transplantation; D051381:Rats; D014184:Transplantation, Homologous
chemical_list: D001663:Bilirubin