title: Controlled evaluation of the beta adrenoceptor blocking drug oxprenolol in anxiety.
abstract: An investigation of the effectiveness of the beta adrenoceptor blocking drug oxprenolol in the treatment of primary clinical anxiety is reported. A controlled double-blind evaluation of oxprenolol versus diazepam and placebo was carried out. The results of the trial showed diazepam to be generally more effective and to produce a more rapid onset of symptom reduction than oxprenolol. The role of beta adrenergic blocking drugs in the treatment of clinical anxiety and related syndromes is discussed.
mesh_terms: D000328:Adult; D001007:Anxiety / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D003975:Diazepam / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D010096:Oxprenolol / Q000009:adverse effects / Q000627:therapeutic use*; D010919:Placebos; D011569:Psychiatric Status Rating Scales; D013997:Time Factors
chemical_list: D010919:Placebos; D010096:Oxprenolol; D003975:Diazepam