title: The computer-assisted morphological classification of acute leukemia. I. Preliminary results.
abstract: The morphology of leukemic lymphoblasts, as seen in the initial routine bone marrow aspirate, of 40 children with ALL has been evaluated using a computer-assisted automated microscope. A statistic, derived from a  combination of the number of macrolymphoblasts and the percentage of cells with no cytoplasm was found to predict response to standard therapy and to identify patients with a high probability of long-term remission as well as a group with a relatively poor response to therapy.
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003936:Diagnosis, Computer-Assisted; D006801:Humans; D007223:Infant; D007945:Leukemia, Lymphoid / Q000145:classification* / Q000473:pathology; D012075:Remission, Spontaneous