Galactorrhea-amenorrhea: psychological interaction with neuroendocrine function.
Further substantiation of the interaction between psychological disease and the onset of galactorrhea-amenorrhea is presented in women who underwent intensive psychometric and neuroendocrine evaluation prior to the use of the dopamine against 2-Br-alpha-ergocryptine (CB-154). Normalization of a previously distorted psychometric test profile in each woman was accompanied by a profound decline in prolactin and an unexpected alteration in the peripheral concentrations of norepinephrine and dopamine-beta-hydroxylase. Cesation of galactorrhea and resumption of menses were observed in each instance.
D000328:Adult; D000568:Amenorrhea / Q000188:drug therapy / Q000209:etiology*; D001971:Bromocriptine / Q000494:pharmacology / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003276:Contraceptives, Oral; D018492:Dopamine Antagonists; D004299:Dopamine beta-Hydroxylase / Q000097:blood; D005260:Female; D005687:Galactorrhea / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007775:Lactation Disorders / Q000209:etiology*; D009638:Norepinephrine / Q000097:blood; D011247:Pregnancy; D011388:Prolactin / Q000378:metabolism; D011581:Psychological Tests; D011602:Psychophysiologic Disorders
D003276:Contraceptives, Oral; D018492:Dopamine Antagonists; D001971:Bromocriptine; D011388:Prolactin; D004299:Dopamine beta-Hydroxylase; D009638:Norepinephrine