title: [Fucidin, its basic properties and place in the modern therapy of suppurative and inflammatory processes].
abstract: Sodium fusidin prepared at the All-Union Research Institute of Antibiotics was studied experimentally and clinically. High antibacterial activity of fusidin especially against methicillin-resistant staphylococci was found. The clinical trials showed high efficacy of fusidin in treatment of perichondritis, osteomyelitis, pyodermia, pseudofurunculosis, multiple abscesses of the skin because of its satisfactory penetration into the skin and cartilage tissues, skin and subcutaneous cellular tissue. The tolerance of the drug by most of the patients was satisfactory.
mesh_terms: D000328:Adult; D001702:Biopharmaceutics; D002648:Child; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004352:Drug Resistance, Microbial; D005672:Fusidic Acid / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D066298:In Vitro Techniques; D007231:Infant, Newborn; D007249:Inflammation / Q000188:drug therapy*; D007700:Kinetics; D008826:Microbial Sensitivity Tests; D013210:Staphylococcus / Q000187:drug effects; D013492:Suppuration / Q000188:drug therapy*; D013997:Time Factors
chemical_list: D005672:Fusidic Acid
vernacular_title: Fuzidin--osnovnye svoĭstva i mesto v sovremennoĭ terapii gnoĭno-vospalitel'nykh protsessov