Hyoscine-N-butylbromide (Buscopan) as a duodenal relaxant in tubeless duodenography.
The efficacy of Buscopan in tubeless duodenography was tested in 48 patients using different routes of administration. The drug led to successful results in 77 to 85 per cent of patients in the dosage used (40 mg), the intravenous route proving the most efficient. The drug is considered superior to Probanthine and glucagon (Glucagon-Lilly) in view of its safety, low incidence of side-effects and efficacy. Follow-through examinations of the small bowel at 1 hour are possible in 33 per cent of patients, although 40 per cent have mild residual abnormalities only.
D002086:Butylscopolammonium Bromide / Q000008:administration & dosage / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004386:Duodenum / Q000000981:diagnostic imaging* / Q000187:drug effects; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006801:Humans; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D008722:Methods; D011292:Premedication; D011859:Radiography; D012602:Scopolamine Derivatives; D013997:Time Factors
D012602:Scopolamine Derivatives; D002086:Butylscopolammonium Bromide