Bone marrow reconstitution using a block grafting technique.
Experiments in rabbits with radiation-induced bone marrow aplasia have demonstrated that intramedullary block grafting is a feasible procedure. This technique requires surgical interference and offers no advantage over intravenous reconstitution. We therefore suggest that it has no value in therapeutic bone marrow transplantation.
D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D001854:Bone Marrow Cells; D001855:Bone Marrow Diseases / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016026:Bone Marrow Transplantation; D004307:Dose-Response Relationship, Radiation; D007958:Leukocyte Count; D011817:Rabbits; D011833:Radiation Injuries, Experimental / Q000097:blood / Q000401:mortality / Q000601:surgery*; D014182:Transplantation, Autologous / Q000379:methods*