title: Pyoderma Gangrenosum and rheumatoid arthritis.
abstract: Two patients had pyoderma gangrenosum and rheumatoid arthritis. Biopsy specimens of the cutaneous ulcers in the patients showed a necrotizing vasculitis. Complement (C3) and immunoglobulins were not detected in the skin lesions. There was no important impairment of cell-mediated immunity observed.
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000276:immunology; D002176:Candida albicans / Q000276:immunology; D002464:Cell Migration Inhibition; D003176:Complement C3 / Q000032:analysis; D004137:Dinitrochlorobenzene / Q000276:immunology; D005260:Female; D006801:Humans; D007104:Immune Adherence Reaction; D007136:Immunoglobulins / Q000032:analysis; D008213:Lymphocyte Activation; D008875:Middle Aged; D009107:Mumps / Q000276:immunology; D011711:Pyoderma / Q000150:complications* / Q000276:immunology / Q000473:pathology; D012867:Skin / Q000473:pathology; D012882:Skin Tests; D014373:Tuberculin / Q000008:administration & dosage
chemical_list: D003176:Complement C3; D004137:Dinitrochlorobenzene; D007136:Immunoglobulins; D014373:Tuberculin