Double-blind investigation of two corticoid preparations for the treatment of eczematous skin disorders. Short communication.
In a double blind fully randomised trial, three Belgian dermatologists independently treated 81 patients suffering from various eczematous skin disorders. After four weeks both the dermatologists and their patients assessed the results of a twice-daily topical application of an ointment containing 17 beta-hydroxy-4-estren-3-one-17-decanoate (nandrolone decanoate, Dexatopic) ointment or a reference ointment. Both the dermatologists' and the patients' assessments of the two preparations showed that there was no significant difference between the two treatments although Dexatopic did seem to have a more favourable profile in the "much improved" area. In the total score decrease, there was an indication that Dexatopic had a more favourable effect than the reference preparation.
D002986:Clinical Trials as Topic; D004485:Eczema / Q000188:drug therapy*; D005443:Flumethasone / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D009277:Nandrolone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D009824:Ointments
D009824:Ointments; D009277:Nandrolone; D005443:Flumethasone