title: The efficacy of "conservative" medical regimens on the rate of hearing losses in Meniere's syndrome: a retrospective computerized statistical analysis.
abstract: The records of 47 patients with Ménière's syndrome were analyzed in a retrospective computerized study to determine the effect of different medical regimens on the long term course of hearing loss. Four treatment groups, including histamine (subcutaneous), other vasodilators (oral), vitamins, and untreated controls were examined. Results suggest that there was no statistically significant difference among the four groups in the rates or absolute level of hearing loss or SRT despite different therapeutic regimens. The ability of these agents to conserve hearing in patients with Ménière's syndrome remains unproven on the basis of clinical and laboratory evidence.
mesh_terms: D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D006309:Hearing; D006311:Hearing Disorders / Q000453:epidemiology / Q000517:prevention & control*; D006632:Histamine / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D008875:Middle Aged; D012189:Retrospective Studies; D013831:Thiamine / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use; D014805:Vitamin B 12 / Q000627:therapeutic use
chemical_list: D014665:Vasodilator Agents; D006632:Histamine; D014805:Vitamin B 12; D013831:Thiamine