title: Regulation of gonadotrophin secretion in rams from birth to sexual maturity. II. Response of the pituitary-testicular axis to LH-RH infusion.
abstract: The response of the pituitary-testicular axis to LH-RH infusion was investigated in rams from birth to sexual maturity. During early postnatal life ram lambs were responsive to LH-RH stimulation and heightened pituitary sensitivity was observed in rams aged 2-3 months. It is suggested that a change in sensitivity of the pituitary-testicular axis occurs at this time and perhaps represents the time of initiation of the pubertal process.
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010902:Pituitary Gland / Q000187:drug effects / Q000254:growth & development*; D012741:Sexual Maturation; D012756:Sheep / Q000502:physiology*; D013737:Testis / Q000187:drug effects / Q000254:growth & development*; D013739:Testosterone / Q000097:blood
chemical_list: D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone