Leucocyte migration inhibitory activity (LMIA) on concanavalin A (Con-A) stimulated human lymphocytes. Comparison of leucocyte migration capillary technique (LMCT), leucocyte migration agarose technique (LMAT), and leucocyte migration fibrinolysis technique (LMFT).
Leucocyte migration and migration inhibition in fibrin medium may reveal new aspects of lymphokine activity associated with immunological inflammation. Leucocyte migration fibrinolysis technique is compared with the leucocyte migration capillary technique and the leucocyte migration agarose technique. In the present model experiment the three methods gave comparable results. The leucocyte migration fibrinolysis technique involves a new principle for detection of lymphokines and can probably be developed to give more exact information about the interrelationship between thrombosis, fibrinolysis and lymphokines.
D000328:Adult; D002464:Cell Migration Inhibition; D003208:Concanavalin A / Q000494:pharmacology*; D005342:Fibrinolysis; D006801:Humans; D066298:In Vitro Techniques; D007962:Leukocytes / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D008222:Lymphokines / Q000276:immunology; D008263:Macrophage Migration-Inhibitory Factors; D008722:Methods; D012685:Sepharose
D008222:Lymphokines; D008263:Macrophage Migration-Inhibitory Factors; D003208:Concanavalin A; D012685:Sepharose