title: [A forty-year survey of radiation therapy of the nasopharyngeal carcinoma].
abstract: Dueing the last forty years, 295 patients with carcinoma of the nasopharynx were admitted to our department. Dur to retarded discovery, the total five-year survival rate amounts to only 15.5% of all patients admitted. In 48.5%, the first symptom was a swelling of the lymphatic ganglions at the neck. Squamous cell carcinoma with 44.2% ranges at the first place followed by retotheliosarcoma with 11% and lympho-epithelioma with 6.4%. Three periods of therapy are confronted. During the first one, brachyradium and teleradium were used; during the second, brachyradium and telecobalt; during the third period, telecobalt and high-energy electrons were employed. Most important, after all, is not the ionization technique but the stage with a 47.1% five-year survival rate in T1N0 as compared to T2N0 with 28.6% and T1N1 with 19.4%. Lympho-epitheliomas with a five-year survival rate of 38.6% offer the best prognosis in contradistinction to sarcomas with 25% and squamous cell carcinomas with 15.04%. At the moment, investigations are going on to verify if afterloading techniques using 60Co are preferable to conventional irradiation techniques.
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000150:complications; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008223:Lymphoma / Q000532:radiotherapy; D016403:Lymphoma, Large B-Cell, Diffuse / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary; D010610:Pharyngeal Neoplasms / Q000175:diagnosis / Q000532:radiotherapy*; D011379:Prognosis; D011867:Radioisotope Teletherapy; D013997:Time Factors
chemical_list: D003037:Cobalt Radioisotopes
vernacular_title: Bericht uber 40 Jahre Strahlentherapie des Epipharynxkarzinoms