title: Neuropsychobiology of affective disorders. Some methodological considerations.
abstract: Amine hypothesis is neither an adequate nor a sufficient postulate in understanding the neuropsychobiology of affective disorders. Interactions and balance between various mechanisms and factors may be important. Better techniques and methodology need to be used and a more comprehensive approach seems to be necessary in formulating meaningful research strategies. The present paper reexamines someaspects of the available data and suggests a few approaches in the sutdy and elucidation of neruophychobiology of affective disorders.
mesh_terms: D000342:Affective Symptoms / Q000378:metabolism*; D000928:Antidepressive Agents / Q000627:therapeutic use; D001921:Brain / Q000378:metabolism; D002395:Catecholamines / Q000378:metabolism*; D003584:Cytological Techniques; D004041:Dietary Fats / Q000378:metabolism; D006801:Humans; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use; D011941:Receptors, Adrenergic / Q000502:physiology; D011950:Receptors, Cholinergic / Q000502:physiology; D012107:Research Design; D013574:Synaptosomes / Q000502:physiology
chemical_list: D000928:Antidepressive Agents; D002395:Catecholamines; D004041:Dietary Fats; D008996:Monoamine Oxidase Inhibitors; D011941:Receptors, Adrenergic; D011950:Receptors, Cholinergic