title: The present status of highly selective vagotomy.
abstract: Peptic ulcer has been the subject of extensive investigation in the search for a curative operation free of complications. Highly selective vagotomy is an elegant physiological approach to the problem, and has excited widespread interest. The reported results in uncomplicated duodenal ulcer disease indicate an almost nil mortality, a very low incidence of recurrent ulceration, a marked reduction in basal and stimulated acid secretion, and little or no interference with gastric emptying, hormone metabolism, or pancreatic and biliary function. The good clinical results at one year appear to be maintained at five years. Its use in the management of gastric ulceration and the complications of peptic ulcer disease also appears promising.
mesh_terms: D004381:Duodenal Ulcer / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications; D013276:Stomach Ulcer / Q000601:surgery*; D014628:Vagotomy