title: Placental lactogen (chorionic mammotrophin) in the field vole, Microtus agrestis, and the bank vole, Clethrionomys glareolus.
abstract: Placental lactogen has been detected in the field vole, Microtus agrestis, and the bank vole, Clethrionomys glareolus, using a co-culture technique. In field voles this activity could be detected from about day 8 of pregnancy to shortly before term, and stimulated both mouse and vole mammary gland to secrete in vitro. Partial immunological cross-reaction was detected in a radioimmunoassay system between rat prolactin and either extracts of vole pituitaries or media on which vole pituitaries had been cultured; vole placental lactogen showed no cross-reaction with rat prolactin. One site of origin for this hormone is probably the trophoblastic giant cells.
mesh_terms: D000818:Animals; D003411:Arvicolinae / Q000502:physiology*; D003429:Cross Reactions; D005260:Female; D008321:Mammary Glands, Animal / Q000378:metabolism; D010903:Pituitary Gland, Anterior / Q000502:physiology; D010920:Placenta / Q000502:physiology; D010928:Placental Lactogen / Q000032:analysis*; D011247:Pregnancy; D011388:Prolactin / Q000276:immunology; D011863:Radioimmunoassay; D012377:Rodentia / Q000502:physiology*; D013268:Stimulation, Chemical
chemical_list: D011388:Prolactin; D010928:Placental Lactogen