Evidence for an association between univalent Y chromosomes and spermatoycte loss in XYY mice and men.
It has been observed previously that there is an association between sex chromosome pairing failure during meiosis and spermatocyte death. An hypothesis is advanced suggesting a similar association between a disruption of sex chromosome pairing (specifically, a failure of Y chromosome pairing) and spermatocyte loss in XYY mice and men.
D000818:Animals; D006801:Humans; D008297:Male; D008540:Meiosis; D008677:Metaphase; D051379:Mice; D008954:Models, Biological; D012729:Sex Chromosome Aberrations / Q000473:pathology*; D012730:Sex Chromosomes; D013090:Spermatocytes; D013091:Spermatogenesis; D013094:Spermatozoa; D014997:XYY Karyotype / Q000235:genetics / Q000473:pathology*; D014998:Y Chromosome