title: [Corneal changes after implantation of intralamellar teflon-membranes (author's transl)].
abstract: After intralamellar implantation of Teflon-membranes (4,0 mm/0,125 mm) without perforation there is an epithelial thinning over the membrane after 6 days, after 15 days metachromatical staining over the membrane is reduced, after 21 days there is a central defect of the cornea over the membrane and after 28 days the membrane is pushed out of the cornea. When Teflon-membranes (4,0 mm/0,125 mm) are inserted with one central perforation or three perforations of 1 mm epithelial thinning, reduced metachromasia and defects of the cornea over the membrane occurred later. But even these membranes are pushed out of the cornea after some time. The results with thinner Teflon-membranes (4.0 mm/0.05 mm) do not show much difference. The reason for the reduced metachromasia of the cornea over Teflon-membranes seems to be a lower rate of syntheses of glycosaminoglycanes because of the reduced glucose content in this part of the cornea. As the experiments with the intracorneal control-pockets without implantation of a Teflon-membrane show, wound-healing is not responsible for the reduced metachromasia over the membrane.
mesh_terms: D000818:Animals; D003316:Corneal Diseases / Q000139:chemically induced* / Q000473:pathology; D005129:Eye Foreign Bodies; D005549:Foreign-Body Reaction; D007909:Lenses / Q000009:adverse effects; D008297:Male; D011138:Polytetrafluoroethylene / Q000009:adverse effects*; D019736:Prostheses and Implants / Q000009:adverse effects; D011817:Rabbits
chemical_list: D011138:Polytetrafluoroethylene
vernacular_title: Hornhautveränderungen nach Teflonplattenimplantation