Expression of the plasmid pKM101--determined DNA repair system in recA- and lex- strains of Escherichia coli.
pKM101, a plasmid R factor of the N compatibility group increases methylmethane sulfonate mutagenesis and diminishes UV-killing in recA+ LEX+ and recA+ lex- strains, , but not in recA-lex+ strains. The induction of a "reclex" dependent colicin is not present in lex- strains carrying the pKM101 factor. These facts indicate that pKM101 acts through an error-prone DNA repair system which is recA+ dependent, but not lex+ dependent.
D003227:Conjugation, Genetic; D004260:DNA Repair; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000378:metabolism*; D005111:Extrachromosomal Inheritance; D009154:Mutation; D010957:Plasmids; D011995:Recombination, Genetic; D012486:Salmonella typhimurium / Q000378:metabolism; D013307:Streptomycin / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology; D014364:Tryptophan / Q000378:metabolism
D014364:Tryptophan; D013752:Tetracycline; D013307:Streptomycin