Experimental research on endotoxic shock in urology.
The endotoxic shock in urological surgery is more frequent due to the increased incidence of the gram-negative infections. More toxic than septic it suggests the hypothesis of a generalized Sanarelli-Schwartzman hypersensitivity phenomenon with hypercoagulation and microthromboses of small vessels. The hypothesis experimentally tested hold good in most cases at the same time requiring an anti-coagulant therapy as an improving effect.
D000818:Animals; D001437:Bacteriuria / Q000150:complications; D001777:Blood Coagulation / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D004211:Disseminated Intravascular Coagulation / Q000503:physiopathology; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D004731:Endotoxins / Q000494:pharmacology; D004926:Escherichia coli; D004927:Escherichia coli Infections / Q000503:physiopathology; D005342:Fibrinolysis / Q000187:drug effects; D012772:Shock, Septic / Q000209:etiology* / Q000503:physiopathology; D014517:Ureteral Obstruction / Q000503:physiopathology; D014552:Urinary Tract Infections / Q000150:complications*; D014666:Vasomotor System / Q000503:physiopathology
D004731:Endotoxins