title: Food additives and hyperkinesis: a controlled double-blind experiment.
abstract: A double-blind crossover trial involving a control diet and a diet eliminating artificial flavors, colors, and natural salicylates as recommended by Feingold was conducted on 15 hyperkinetic children. Teachers and parents observed the children for one month prior to treatment, using standardized rating scales. Both parents and teachers reported fewer hyperkinetic symptoms on the K-P diet as compared to the pretreatment baseline. The teachers noted a highly significant reduction of symptoms on the K-P diet as compared to the control diet but the parents did not. The control diet ratings did not differ from the baseline period ratings for either parents or teachers. It is concluded that the K-P diet may reduce hyperkinetic symptoms, though this result is put forth with caution in view of several features inherent in the present study which need further evaluation, including objective measures of change, manipulation of the independent variable, and reducing the independent variable to more specific components.
mesh_terms: D002648:Child; D002986:Clinical Trials as Topic; D005069:Evaluation Studies as Topic; D005247:Feeding Behavior; D005503:Food Additives / Q000009:adverse effects*; D006801:Humans; D006948:Hyperkinesis / Q000139:chemically induced / Q000178:diet therapy*; D009751:Nutritional Requirements; D012459:Salicylates
chemical_list: D005503:Food Additives; D012459:Salicylates