Bilateral cervical transplantation of canine kidneys for study of canine renal preservation.
Bilateral cervical autotransplantation of canine kidneys is described for comparative study of renal preservation techniques. Data are obtained from kidneys preserved by (1) initial intravascular flushing with modified Collins' C3 solution (Ursol) followed by cold storage, and (2) pulsatile perfusion (MOX 100). Preharvest condition of the donor and ischemia times are identical, thus eliminating major sources of potential data variation. Renal function studies performed at periodic intervals demonstrated better initial function for machine preservation but no difference after one to two-month period.
D000818:Animals; D003080:Cold Temperature; D004285:Dogs; D016030:Kidney Transplantation; D009926:Organ Preservation / Q000379:methods; D010477:Perfusion; D014021:Tissue Preservation; D014182:Transplantation, Autologous