Metrizoic acid (Isopaque coronar) used in man for cardiac angiography.
Isopaque Coronar, a radiopaque agent, was given (10,000 injections) to 2,028 patients during angiocardiographic studies done over a three-year period. With two exceptions, all complications occurred during right coronary artery injection. Seven cases of ventricular fibrilation, and 5 of marked bradycardia/asystole, were associated with injection of the medium. Isopaque Coronar is well tolerated by patients during cardiac examinations. Factors which may help to explain the low complication rate are discussed.
D000790:Angiocardiography; D004562:Electrocardiography; D006321:Heart / Q000000981:diagnostic imaging*; D006323:Heart Arrest / Q000139:chemically induced; D006801:Humans; D007463:Iodobenzoates / Q000009:adverse effects; D008794:Metrizoic Acid / Q000009:adverse effects*; D009203:Myocardial Infarction / Q000139:chemically induced; D014693:Ventricular Fibrillation / Q000139:chemically induced
D007463:Iodobenzoates; D008794:Metrizoic Acid