title: [Comparative study of the effect of antibiotics-aminoglycosides on pseudotuberculosis bacterium in vitro and in vivo].
abstract: It was found that 229 out of 230 strains of pseudotuberculosis microbes tested were sensitive to aminoglycosides, such as streptomycin, monomycin, neomycin, kanamycin and gentamicin. The MIC did not exceed 50 gamma/ml. One strain of J. pseudotuberculosis was multiresistant to streptomycin, tetracycline, levomycetin and penicillin. The above aminoglycosides (streptomycin, monomycin, kanamycin and gentamicin) were active in the treatment of albino mice with experimental pseudotuberculosis.
mesh_terms: D000617:Aminoglycosides / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D004341:Drug Evaluation; D004352:Drug Resistance, Microbial; D066298:In Vitro Techniques; D051379:Mice; D015007:Yersinia / Q000187:drug effects*; D015009:Yersinia Infections / Q000382:microbiology*; D015012:Yersinia pseudotuberculosis Infections / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000617:Aminoglycosides
vernacular_title: Sravnitel'noe izuchenie deĭstviia antibiotidov-aminoglikozido na psevdotuberkuleznyĭ mikrob in vitro i in vivo