[Dynamics of agglutination in birds artificially infected with Salmonella gallinarum-pullorum and Salmonella typhimurium and treated with sulfaguanidine and furazolidone].
Canadian Leghorn chickens were used to study the effect of sulfaguanidine and furazolidon on the dynamics of blood agglutinin formation. The birds were artificially infected with Salmonella gallinarum-pullorum and Salmonella typhimurium. At various intervals following infection they were treated with sulfaguanidine 1% tablets and 0.04% furazolidon. The level of agglutinins was determined by the methods of Huddleson (whole blood agglutination reaction), the fast serum agglutination, the method after Wright, and the indirect hemagglutination reaction. It was found that the agglutinin level in birds treated in the course of ten days with the chemotherapeutics mentioned prior to their infection did not change. The use of these chemotherapeutics parallel to the infection of the test birds and ten days later inhibited agglutinin formation. This was more pronouncedly expressed in birds treated with furazolidon. The delayed use of these therapeutic means did not inhibit substantially the level of blood agglutinins.
D000373:Agglutinins; D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D002645:Chickens; D005260:Female; D005664:Furazolidone / Q000627:therapeutic use*; D006146:Guanidines / Q000627:therapeutic use*; D008297:Male; D011201:Poultry Diseases / Q000188:drug therapy* / Q000276:immunology; D012481:Salmonella Infections, Animal / Q000188:drug therapy* / Q000276:immunology; D012486:Salmonella typhimurium; D013414:Sulfaguanidine / Q000627:therapeutic use*
D000373:Agglutinins; D000907:Antibodies, Bacterial; D006146:Guanidines; D013414:Sulfaguanidine; D005664:Furazolidone
Prouchvane dinsmikata na aglutininite pri ptitsi, izkustveno infektirani sus Salmonella gallinarum-pullorum i Salmonella typhimurium i tretirani sus sulfaguanidin i furazolidon