Is the antioxidant butylated hydroxytoluene a depigmenting agent in man?
Because of the allegation that butylated hydroxytoluene produced depigmentation in man, a prospective study was performed. Sixteen adult darkly pigmented males received daily occlusive applications for 60 days. Depigmentation was not observed.
D000328:Adult; D000975:Antioxidants / Q000494:pharmacology*; D002084:Butylated Hydroxytoluene / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D003408:Cresols / Q000494:pharmacology*; D006801:Humans; D008297:Male; D010858:Pigmentation / Q000187:drug effects*; D011446:Prospective Studies
D000975:Antioxidants; D003408:Cresols; D002084:Butylated Hydroxytoluene