Autoimmunity induced in rabbits by rinderpest virus.
During rinderpest virus infection in rabbits, 19S cold hemagglutinating antibody against rabbit erythrocytes and 7S anti-nuclear antibody, which reacts with the nuclei and/or the nuclear membranes in immunofluorescent staining, were demonstrated. Virus infection that affected the thymus-dependent immune functions was speculated to act as a trigger for the production of these two autoantibodies.
D000818:Animals; D000974:Antibodies, Antinuclear / Q000032:analysis; D000917:Antibody Formation; D001323:Autoantibodies / Q000032:analysis*; D003080:Cold Temperature; D005260:Female; D005455:Fluorescent Antibody Technique; D006388:Hemagglutinins; D008297:Male; D009500:Neutralization Tests; D011817:Rabbits; D012302:Rinderpest virus / Q000276:immunology*
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D006388:Hemagglutinins