The genetic effects of elevated temperature in the yeast, Saccharomyces cerevisiae.
The growth of yeast cultures at supra-optimal temperatures up to 39 degrees C and exposure in non-nutrient solution up to 52 degrees C has been examined for the induction of genetic change. Both sets of conditions lead to the induction of mutation to antibiotic resistance, mitotic gene conversion, crossing-over and mitotic chromosomal non-disjunction.
D000818:Animals; D002869:Chromosome Aberrations; D003434:Crossing Over, Genetic; D004351:Drug Resistance; D006358:Hot Temperature; D008938:Mitosis; D009154:Mutation; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae / Q000502:physiology*