title: Pancreatic APUD cells in older chick embryos, with special reference to their identity.
abstract: Pancreatic APUD cells showing formaldehyde-induced fluorescence in Black Australorp chick embryos of nine to eighteen days of incubation, proved, on subsequent staining and silver impregnation, to be A, B, D and, from sixteen days, enterochromaffin (EC) cells. EC and D cells were scattered in the exocrine parenchyma, the latter cells increasing with time. Some group of B cells were associated with large A islets from the ninth day of incubation onwards. The composition of A islets (A and some D cells) and B islets (B and some D cells) and the distribution attained (A islets in the splenic and third lobes; B islets in all lobes), accords with the situation reported for adults.
mesh_terms: D000367:Age Factors; D000818:Animals; D001679:Biogenic Amines / Q000032:analysis*; D002642:Chick Embryo; D004295:Dihydroxyphenylalanine / Q000378:metabolism; D004759:Enterochromaffin Cells; D007515:Islets of Langerhans / Q000032:analysis* / Q000166:cytology / Q000196:embryology; D008856:Microscopy, Fluorescence; D009490:Neurosecretory Systems / Q000166:cytology
chemical_list: D001679:Biogenic Amines; D004295:Dihydroxyphenylalanine