Rifampicin and chloramphenicol effects on DNA replication in ultraviolet-damaged Escherichia coli B/r WP2 thy trp.
The antibiotic rifampicin, which blocks specifically RNA synthesis, limited DNA replication in Escherichia coli strain B/r WP2 thy trp after an increase of about 50%, when added to the incubation medium at the time of replication initiation after ultraviolet fluences of 20 J/m2...
D002701:Chloramphenicol / Q000494:pharmacology*; D004261:DNA Replication / Q000187:drug effects / Q000528:radiation effects*; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D007700:Kinetics; D012293:Rifampin / Q000494:pharmacology*; D014466:Ultraviolet Rays
D002701:Chloramphenicol; D012293:Rifampin