title: Comparative study of intravenous ketoprofen versus aspirin.
abstract: In order to assess the analgesic effect of an injectable preparation of ketoprofen, a double-blind comparative study was conducted against a soluble form of acetylsalicylic acid of known efficacy, widely used in the clinic. Only one indication was considered for inclusion in the trial, namely discogenic sciatica. We found no significant statistical difference between these two products, considering the criteria used. The time of onset of effect was, on average, 30 minutes and the mean duration of activity was 4 hours. The two products were well tolerated.
mesh_terms: D000328:Adult; D000368:Aged; D000700:Analgesics; D001241:Aspirin / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D001577:Benzophenones / Q000008:administration & dosage*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007660:Ketoprofen / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010919:Placebos; D012585:Sciatica / Q000188:drug therapy*
chemical_list: D000700:Analgesics; D001577:Benzophenones; D010919:Placebos; D007660:Ketoprofen; D001241:Aspirin