[Sexchromatin determination in a corneal graft in adult cystinosis (author's transl)].
On the basis of the distribution of F-bodies (Y-Chromatin) and Barr-bodies (X-Chromatin) in a lamellar keratoplasty from a female donor and in the surrounding male corneal tissue of a 55-year-old male patient with adult cystinosis a few female corneal epithelial cells could be identified 7 years after corneal tissue-graft had been performed. It was concluded that after keratoplasty epithelial cells grow into each other, i.e. from the graft to the host tissue and vice versa. The fact that even after 7 years female epithelial cells from the donor can still be detected is put down to the metabolic condition resulting in cystinosis.
D016039:Corneal Transplantation; D003554:Cystinosis / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012728:Sex Chromatin / Q000032:analysis*; D014184:Transplantation, Homologous
Sexchromatinbestimmung in einem Hornhauttransplantat bei Erwachsenenzystinose