title: [Effect of hydrocortisone on some indices of cardiac activity and of the greater circulation in acquired heart defects].
abstract: The catheterization technique was used to study the effect of 100 mg of water soluble hydrocortisone "Russel" upon the cardiac activity and greater circulation in patients with acquired heart diseases. Hydrocortisone was found to produce different effects upon the cardiac output and tonicity of the greater circulation vessels--increases or decreases them, or does not change at all. The varying dynamics of these indices serves as a manifestation of the optimizing effect of hydrocortisone on the cardiovascular system, depends on the initial values of the parameters in question, and is directed towards normalizing the oxygen consumption in the body (its blood flow). No direct correlation was found between the cardiac output and the pressure in the ventricles in patients with acquired heart diseases prior to and following hydrocortisone administration.
mesh_terms: D001775:Blood Circulation / Q000187:drug effects*; D006328:Cardiac Catheterization; D002302:Cardiac Output / Q000187:drug effects; D002986:Clinical Trials as Topic; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D006325:Heart Atria / Q000187:drug effects; D006334:Heart Function Tests; D006349:Heart Valve Diseases / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use*; D013997:Time Factors; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D006854:Hydrocortisone
vernacular_title: Vliianie gidrokortizona na nekotorye pokazateli serdechnoĭ deiatel'nosti i krovoobrashcheniia bol'shogo kruga u bol'nykh priobretennymi porokami serdtsa