title: Infected aortic bifurcation grafts: experience with fourteen patients.
abstract: The experience with 14 patients with infected aortic bifurcation grafts has been reviewed. Factors which appeared to predispose to infection in 11 patients included "re-do" operations, concomitant cholecystectomy or gastrostomy, and ruptured abdominal aneurysm. A mixture of gastrointestinal organisms was responsible for the infections. The pathogenesis, presentation, and treatment varied according to whether the proximal or distal anastomosis was involved or not. Aortoduodenal communications were present in five patients; they presented with gastrointestinal bleeding or septicemia. One patient survived as a result of early, aggressive surgical therapy. Infection presented at the distal anastomosis in nine patients, either as groin abscess or false aneurysm. Conservative therapy failed in the majority of patients but apparently was successful in three of five patients in whom infection did not involve the intra-abdominal portion of the graft. When infection does involve the intra-abdominal portion of the graft, then the graft must be excised also. Revascularization often can be accomplished with extra-anatomic bypasses of prosthesis or autogenous material, depending on the characteristics of the individual patient. Regardless of the mode of presentation or the site of infection, the early institution of judicious surgical management offers the best chance of success in these patients, and temporization usually leads to failure.
mesh_terms: D001014:Aortic Aneurysm / Q000601:surgery*; D001157:Arterial Occlusive Diseases / Q000601:surgery*; D001424:Bacterial Infections / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D001442:Bacteroides Infections / Q000209:etiology; D001807:Blood Vessel Prosthesis; D002177:Candidiasis / Q000209:etiology; D004927:Escherichia coli Infections / Q000209:etiology; D006801:Humans; D011512:Proteus Infections / Q000209:etiology; D013290:Streptococcal Infections / Q000209:etiology