The time of appearance of Ia antigens during spermatogenesis in the mouse.
Ia specificities were studied on germinal cells from C3H and 129 mice by using an AT.H anti-AT.L antiserum. By absorption experiments and immunofluorescence studies on sections of testes from mice of various ages, we were able to detect Ia specificities on cells of the germinal line from primary spermatocyte to spermatozoa. Ia specificities were not detectable on gonocytes or spermatogonia.
D000375:Aging; D000818:Animals; D002469:Cell Separation; D005455:Fluorescent Antibody Technique; D007109:Immunity; D007163:Immunosorbent Techniques; D007519:Isoantigens / Q000032:analysis*; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D013087:Spermatids / Q000276:immunology; D013090:Spermatocytes / Q000276:immunology; D013091:Spermatogenesis; D013094:Spermatozoa / Q000276:immunology
D007519:Isoantigens