Space flight effects on the hemopoietic function of bone marrow of the rat.
The 22-d orbital flight of rats onboard the Cosmos-605 biosatellite was followed by inhibition of erythroblastosis, alteration in the morphology of megakaryocytes, and stimulation of myelopoiesis. These changes returned to normal 27 d postflight. The colony-forming capacity and pattern of differentiation of hemopoietic stem cells of bone marrow of flight rats remained undisturbed.
D000818:Animals; D001853:Bone Marrow / Q000502:physiology*; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D005260:Female; D006410:Hematopoiesis; D008297:Male; D008533:Megakaryocytes / Q000502:physiology*; D051379:Mice; D008938:Mitosis; D051381:Rats; D013026:Space Flight; D014183:Transplantation, Heterologous; D014893:Weightlessness