title: Aspects of the toxicology of chloroprene: immediate and long-term effects.
abstract: The maximum permissible concentration (MPC) of chloroprene was set at 2 mg/m3 in the USSR in the 1940's. The existing MPC  is 4 mg/m3. The threshold of systemic effects as a result of chronic chloroprene exposure is l.69 mg/m3. However, the threshold for embryotoxic and mutagenic effects is 0.15 mg/m3. In consideration of this information, setting a new MPC for chloroprene at 0.05 mg/m3 is recommended.
mesh_terms: D000328:Adult; D000818:Animals; D001772:Blood Cell Count; D002070:Butadienes / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000633:toxicity; D002490:Central Nervous System / Q000187:drug effects; D002617:Chemical Industry; D004622:Embryo, Mammalian / Q000187:drug effects; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008452:Maximum Allowable Concentration; D051379:Mice; D008810:Mice, Inbred C57BL; D008875:Middle Aged; D009153:Mutagens; D009784:Occupational Diseases / Q000139:chemically induced; D011247:Pregnancy; D051381:Rats; D013091:Spermatogenesis / Q000187:drug effects; D013997:Time Factors; D014724:Vestibular Function Tests
chemical_list: D002070:Butadienes; D009153:Mutagens