Effect of cell-wall skeleton of Mycobacterium bovis BCG on cell-mediated cytotoxicity in tumor-bearing mice.
Effect of oil-attached BCG cell-wall skeleton (BCG-CWS) on cell-mediated cytotoxicity in tumor-being mice was investigated using the allograft system. It was found that the treatment with oil-attached BCG-CWS was able to elevate the immunolgically depressed state of tumor-bearing mice to a normal level as determined by chromium release assay.
D000276:Adjuvants, Immunologic; D000818:Animals; D001500:BCG Vaccine; D002473:Cell Wall / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D012515:Mast-Cell Sarcoma / Q000276:immunology; D008545:Melanoma / Q000276:immunology; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009163:Mycobacterium bovis / Q000276:immunology*; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000276:immunology*; D014184:Transplantation, Homologous
D000276:Adjuvants, Immunologic; D001500:BCG Vaccine