[The effect of cortisone on lympho-reticular cells with specific enzyme activity of the white pulp of rat spleen].
By its destructive effect on the small lymphocyte, cortisone was used to separate the T-lymphocyte from other cells which might be found in the same areas. A reticular cell showing a predominant 5' nucleotidasic activity distinct from that of the phosphatasic acid appeared to be a component of the thymus-dependent areas in the splenic white pulp of Rat. Specific correlations seem to exist between this reticular cell and T-lymphocytes. This histoenzymatic feature involves the reticular cell in the process of maturation of the small lymphocyte.
D000818:Animals; D000831:Animals, Newborn; D003348:Cortisone / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D009708:Nucleotidases / Q000378:metabolism; D051381:Rats; D013154:Spleen / Q000187:drug effects / Q000254:growth & development / Q000276:immunology*; D013601:T-Lymphocytes / Q000201:enzymology / Q000378:metabolism
D009708:Nucleotidases; D003348:Cortisone
Les particularités de l'action cortisonique sur des éléments lympho-réticulaires à activité enzymatique spécifique de la pulpe blanche splénique du rat