Radiotherapy of Ewing's sarcoma. Local control with and without intensive chemotherapy.
Primary tumor control rates were studied in two groups of patients with Ewing's tumor. They received high doses of radiation combined with a standard chemotherapy regimen incorporating multiple agents. Another 17 had either less chemotherapy or none at all. The data suggest that treatment dose and control are correlated and that intensive chemotherapy contributes to destruction of the primary tumor.
D000293:Adolescent; D001859:Bone Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D002648:Child; D002675:Child, Preschool; D003520:Cyclophosphamide / Q000627:therapeutic use; D003609:Dactinomycin / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D011882:Radiotherapy, High-Energy; D012512:Sarcoma, Ewing / Q000188:drug therapy / Q000532:radiotherapy*; D014750:Vincristine / Q000627:therapeutic use
D003609:Dactinomycin; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide