[Non-resecting surgery for gastroduodenal ulcer. I. Pathophysiological principles (author's transl)].
Selective proximal vagotomy with pyloroplasty is a method which permits ulcers to be operated on with less morphological and pathophysiological disturbances than is possible with any other method. After ingestion, a reactive yet reduced acid secretion is still possible through the gastrin stimulus. The retained vagal antral release of gastrin seems to be without importance to the denervated delomorphous cells. Side effects of this type of vagotomy are small. The disturbances of motility and evacuation which also occur here can easily be corrected by an additional pyloroplasty suitable in shape and function.
D000818:Animals; D001646:Bile / Q000378:metabolism; D004285:Dogs; D004381:Duodenal Ulcer / Q000503:physiopathology / Q000601:surgery*; D005750:Gastric Juice / Q000378:metabolism; D005755:Gastrins / Q000378:metabolism; D005769:Gastrointestinal Motility; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000494:pharmacology; D010189:Pancreatic Juice / Q000378:metabolism; D011178:Postgastrectomy Syndromes; D011379:Prognosis; D011446:Prospective Studies; D011708:Pylorus / Q000601:surgery; D012008:Recurrence; D013276:Stomach Ulcer / Q000503:physiopathology / Q000601:surgery*; D014628:Vagotomy / Q000009:adverse effects
D005755:Gastrins; D007328:Insulin
Die nich-resezierende Chirurgie des Gastro-Duodenal-Ulkus. I. Pathophysiologische Grundlagen