title: The effect of disodium cromoglycate on human performance, alone and in combination with ethanol.
abstract: Seventeen paid volunteer subjects were used in a double-blind crossover experiment to investigate the effects of disodium cromoglycate (DSCG), alone and in combination with ethanol, on human perceptual, cognitive and motor performance. DSCG (40 mg) had little effect when given alone. When administered with ethanol (0-75 g/kg), DSCG did not significantly modify the ethanol-induced decrement in performance except in the complex reaction time test.
mesh_terms: D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D003071:Cognition / Q000187:drug effects*; D004205:Cromolyn Sodium / Q000494:pharmacology*; D003864:Depression, Chemical; D004347:Drug Interactions; D000431:Ethanol / Q000097:blood / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D009048:Motor Skills / Q000187:drug effects*; D010465:Perception / Q000187:drug effects*; D010919:Placebos; D011930:Reaction Time / Q000187:drug effects
chemical_list: D010919:Placebos; D000431:Ethanol; D004205:Cromolyn Sodium