Vertebral osteomyelitis as a complication of Pseudomonas aeruginosa pneumonia.
A patient with Pseudomonas aeruginosa pneumonia treated with gentamicin subsequently developed thoracovertebral osteomyelitis over the area of a preexisting compression fracture. Increasing back pain and progressive destruction with sclerosis of the involved vertebrae led to a needle biopsy examination of the vertebrae which showed evidence of chronic osteomyelitis and grew P aeruginosa on culture. P aeruginosa bacteremia was documented six months before the demonstration of the organism in the vertebrae. Treatment with a combination of gentamicin and carbenicillin coupled with bed rest cured the vertebral osteomyelitis.
D002228:Carbenicillin / Q000627:therapeutic use; D050723:Fractures, Bone / Q000000981:diagnostic imaging; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000382:microbiology; D011014:Pneumonia / Q000150:complications* / Q000000981:diagnostic imaging / Q000382:microbiology; D011552:Pseudomonas Infections / Q000150:complications*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D011859:Radiography; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging
D005839:Gentamicins; D002228:Carbenicillin