title: The primary empty sella syndrome.
abstract: An extreme and unique manifestation of the primary empty sella syndrome was found by the pneumoencephalographic demonstration of air in the sella turcica of a short, 18-year-old, prepubescent female with primary amenorrhea. Gonadotropins and growth hormone were selectively deficient and not stimulated by luteinizing hormone releasing hormone (LHRH) or insulin induced hypoglycemia, respectively.
mesh_terms: D000293:Adolescent; D000568:Amenorrhea / Q000209:etiology; D005260:Female; D006801:Humans; D007018:Hypopituitarism / Q000150:complications*; D011627:Puberty; D012658:Sella Turcica; D013577:Syndrome