Experimental pyelonephritis in the monkey. IV. Vesicoureteral reflux and bacteria.
A model was designed to study the relation between urinary infection and vesicoureteral, low-grade, total reflux. Surgical alteration of the ureterovesical junction produced grade 2 vesicoureteral reflux in seven of 13 animals. In the other six animals, surgery had rendered the vesicoureteral junction marginally competent and chronic bladder infection caused grade 2 reflux. It was found that grade 2 vesicoureteral reflux in the adult monkey neither prolongs urinary tract infection nor causes continued renal infection.
D000818:Animals; D004195:Disease Models, Animal; D004927:Escherichia coli Infections / Q000150:complications*; D005260:Female; D005547:Foreign Bodies / Q000150:complications; D000882:Haplorhini; D008251:Macaca; D010070:Oxalates; D011512:Proteus Infections / Q000150:complications*; D011513:Proteus mirabilis; D011704:Pyelonephritis / Q000139:chemically induced / Q000209:etiology*; D001743:Urinary Bladder / Q000601:surgery; D014718:Vesico-Ureteral Reflux / Q000150:complications*
D010070:Oxalates