title: Lack of increase in DNA crosslinking in Drosophila melanogaster with age.
abstract: Adult Drosophila melanogaster fruit flies ranging in age from 2 to 7.5 weeks with a median colony survival time of 6.4 weeks at 25 degrees C showed no increase in DNA crosslinking with age. The purified denatured DNA used for crosslink determinations varied in molecular weight from 2.02 to 3.84 times 10(5) daltons and was crosslinked to the extent of 6.2-8.8% with no age-related trend.
mesh_terms: D000375:Aging; D000818:Animals; D004247:DNA / Q000032:analysis*; D004331:Drosophila melanogaster; D008040:Genetic Linkage; D008970:Molecular Weight; D009691:Nucleic Acid Denaturation; D009695:Nucleic Acid Renaturation
chemical_list: D004247:DNA