Distribution of polychlorinated biphenyls: structural requirements for accumulation in the mouse bronchial mucosa.
Autoradiography showed that labelled polychlorinated biphenyls with chlorine in positions 2, 41, 5 and hydrogen in positions 3, 31, 6, 61 in the molecule are accumulated in the mouse bronchial mucosa. Further testing of this observation showed that 2, 21, 4, 51-tetrachlorbiphenyl-14C, but not biphenyl-14C, was taken up in the bronchi of mice.
D000818:Animals; D001345:Autoradiography; D001980:Bronchi / Q000378:metabolism*; D005260:Female; D008168:Lung / Q000378:metabolism; D051379:Mice; D008810:Mice, Inbred C57BL; D009092:Mucous Membrane / Q000378:metabolism; D011078:Polychlorinated Biphenyls / Q000378:metabolism*; D011247:Pregnancy; D013329:Structure-Activity Relationship
D011078:Polychlorinated Biphenyls