title: A chronic implant for intracerebral mass spectrometric gasometry in the rhesus monkey.
abstract: A cranial implant was developed to facilitate mass spectrometric gasometry in cerebral tissue of conscious primates. It is permanently fixed to the skull and allows repeated introduction of a Teflon diffusion membrane into the cerebrum. The implant is simple to manufacture and mount. It has been tolerated well with repeated introduction of the catheter for more than 6 mo in 10 rhesus monkeys. The preparation avoids the complication and artifacts of an acute surgical preparation for investigation of cerebral pO2 and CO2.
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D002245:Carbon Dioxide / Q000378:metabolism; D002404:Catheterization / Q000295:instrumentation / Q000662:veterinary; D005260:Female; D000882:Haplorhini; D008251:Macaca / Q000378:metabolism*; D008253:Macaca mulatta / Q000378:metabolism*; D008297:Male; D013058:Mass Spectrometry / Q000295:instrumentation*; D010101:Oxygen Consumption; D010313:Partial Pressure
chemical_list: D002245:Carbon Dioxide