The effect of fat emulsion on essential fatty acid deficiency during intravenous hyperalimentation in pediatric patients.
A series of experiments on puppies and two newborn infants indicates that Intralipid which covered only 4% of the total caloreis, prevented or improved essential fatty acid deficiency in puppies and infants on hyperalimentation. This means that the intravenous fat emulsion, which covers about 2% of the total caloric intake with linoleic acid, still satisfies the essential fatty acid requirement, since half of the fatty acid composition of Intralipid is linoleate.
D000818:Animals; D001774:Blood Chemical Analysis; D001835:Body Weight; D000013:Congenital Abnormalities / Q000178:diet therapy; D003677:Deficiency Diseases / Q000517:prevention & control; D004285:Dogs; D004655:Emulsions; D004933:Esophageal Atresia / Q000178:diet therapy; D005228:Fatty Acids, Essential / Q000032:analysis / Q000097:blood / Q000172:deficiency*; D005260:Female; D006801:Humans; D007082:Ileum / Q000002:abnormalities; D007231:Infant, Newborn; D008099:Liver / Q000032:analysis / Q000473:pathology; D008297:Male; D010288:Parenteral Nutrition; D010289:Parenteral Nutrition, Total / Q000009:adverse effects; D051381:Rats; D013025:Glycine max
D004655:Emulsions; D005228:Fatty Acids, Essential