[Cytotoxicity of aurintricarboxylic acid: inhibition of cell proliferation and of protein synthesis in Allium sativum L. root meristems].
The inhibitory action of aurine-tricarboxylic acid (ATA) on protein synthesis, known in vitro, has been checked in vivo in Allium sativum L. root meristems. Parallel to this inhibition, ATA acts on cell proliferation, on the one hand by preventing the entering of cells into prophase and, on the other hand, by disturbing the process of mitosis.
D001312:Aurintricarboxylic Acid / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D003509:Cyclohexanecarboxylic Acids / Q000494:pharmacology*; D008938:Mitosis / Q000187:drug effects; D010940:Plant Proteins / Q000096:biosynthesis*; D010944:Plants / Q000187:drug effects* / Q000378:metabolism
D003509:Cyclohexanecarboxylic Acids; D010940:Plant Proteins; D001312:Aurintricarboxylic Acid
Sur la cytotoxicité de l'acide aurine-tricarboxylique: inhibition de la prolifération cellulaire et des synthèses protéiques dans les méristèmes radiculaires d'Allium sativum L