A comparison between the lecithin/sphingomyelin ratio of Gluck and other phospholipid values of amniotic fluid.
We have found the lecithin/sphingomyelin ratio of Gluck (L/S ratio) to be very useful for predicting respiratory distress. It correlated reasonably well with three other phospholipid values: the total lecithin content, the acetone-insoluble lecithin content, and the total lecithin/total phospholipids ratio. When the L/S ratio of amniotic fluid was greater than 2.0 there was no respiratory distress, even if the other phospholipid values indicated that the fetal lungs were still immature.
D000096:Acetone / Q000032:analysis; D000653:Amniotic Fluid / Q000032:analysis*; D001787:Blood Group Incompatibility; D002855:Chromatography, Thin Layer; D003720:Densitometry; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010713:Phosphatidylcholines / Q000032:analysis*; D010743:Phospholipids / Q000032:analysis*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012127:Respiratory Distress Syndrome, Newborn / Q000175:diagnosis*; D012204:Rh-Hr Blood-Group System; D013109:Sphingomyelins / Q000032:analysis*
D010713:Phosphatidylcholines; D010743:Phospholipids; D012204:Rh-Hr Blood-Group System; D013109:Sphingomyelins; D000096:Acetone