title: Reversible, titrated deep sedation for major office surgery.
abstract: We have operated upon 446 consecutive patients in the office, using the controlled titrated method of sedation which we have described. We believe the results are superior to the methods in more common use.  A major factor in choosing a narcotic as our one basic drug was the availability of a safe, swift, and effective antidote to it.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000772:Anesthesia, Local / Q000379:methods*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D001919:Bradycardia / Q000139:chemically induced; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D007275:Injections, Intravenous; D008297:Male; D008614:Meperidine / Q000008:administration & dosage / Q000009:adverse effects; D008875:Middle Aged; D009020:Morphine; D009270:Naloxone / Q000008:administration & dosage / Q000009:adverse effects; D012131:Respiratory Insufficiency / Q000139:chemically induced; D013518:Surgery, Plastic; D014839:Vomiting / Q000139:chemically induced
chemical_list: D009270:Naloxone; D009020:Morphine; D008614:Meperidine