Melanocytic activity in leprosy lesions with special reference to cellular infiltrate.
To assess the correlation, if any, between the clinical hypopigmentation in leprosy affected skin and the inflammatory cellular infiltrate in d rmis, skin tissue sections from the maculo-anaesthetic and tuberculoid lesion of 50 cases were studied with Dopa and H & E stains. The results are indicative of (i) proportionate lack of Dopa oxidase activity in the hypopigmented leprosy lesions in commensuration with the relative degree of clinical hypopigmentation; (ii) cellular infiltrate is not related with the clinical hypopigmentation or dopa oxidase activity.
D002648:Child; D005260:Female; D006801:Humans; D007918:Leprosy / Q000150:complications / Q000201:enzymology / Q000473:pathology*; D008297:Male; D008544:Melanocytes / Q000473:pathology*; D014442:Monophenol Monooxygenase / Q000378:metabolism; D010859:Pigmentation Disorders / Q000209:etiology*; D012867:Skin / Q000201:enzymology
D014442:Monophenol Monooxygenase