Meningococcal carrier rates in parts of eastern Nigeria.
A survey of the meningococcal carrier rate was conducted in the Nsukka area (eastern Nigeria) during an interepidemic period. It was found that approximately 10% of 1126 individuals studied carried one serogroup or other. The predominant serogroup was B (58.1%), followed by C (24.2%). The highest percentage of isolates was from the age group 11-20 years (12.00%), followed by the age group 6-10 years (10.5%). The proportion of isolations was only 6.0% in the age group 31 years and above. Isolates from urban communities were resistant to sulfadiazine: 71.43% (group A), 63.9% (group B), 80.0% (group C), and 100% (group D). The percentage of resistant isolates from the villages was lower. Ninety-five per cent of all isolates were sensitive to penicillin, streptomycin, chloramphenicol, trimethoprim, and erythromycin.
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002353:Carrier State / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D004352:Drug Resistance, Microbial; D006801:Humans; D008589:Meningococcal Infections / Q000453:epidemiology*; D009305:Nasopharynx / Q000382:microbiology; D009345:Neisseria meningitidis / Q000187:drug effects / Q000302:isolation & purification; D009549:Nigeria; D012621:Seasons; D013411:Sulfadiazine / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D013411:Sulfadiazine