Imipramine and seizures.
The authors report the case of a psychotic preschool child who manifested a seizure disorder while on imipramine treatment. They note that according to his history and physical exam, the child fell within a group which seems predisposed to this side effect. Although tricyclic antidepressant compounds can be used judiciously with seizure-prone individuals, the authors recommend that alternative modalities be given first consideration.
D002675:Child, Preschool; D004827:Epilepsy / Q000139:chemically induced*; D004832:Epilepsy, Absence / Q000150:complications; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced; D006801:Humans; D007099:Imipramine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008457:Measles / Q000150:complications; D012561:Schizophrenia, Childhood / Q000188:drug therapy*
D007099:Imipramine