Evaluation of the action of some drugs on the blood supply of the myocardium in rabbits by means of the test of 125J absorption.
In experiments with rabbits, the influence of nitroglycerine, sorbonite and aminophylline on blood flow through the myocardium was compared by the radioisotope method. Adrenaline, noradrenaline and isoprenaline diminished capillary blood flow in the heart of rabbits. Persantine had no effect on capillary circulation in the heart of the experimental animals.
D000818:Animals; D002196:Capillaries / Q000187:drug effects; D002395:Catecholamines / Q000494:pharmacology; D003331:Coronary Vessels / Q000187:drug effects*; D005260:Female; D007457:Iodine Radioisotopes; D008297:Male; D005996:Nitroglycerin / Q000494:pharmacology; D011817:Rabbits; D012039:Regional Blood Flow / Q000187:drug effects; D014665:Vasodilator Agents / Q000494:pharmacology
D002395:Catecholamines; D007457:Iodine Radioisotopes; D014665:Vasodilator Agents; D005996:Nitroglycerin