[New developments in insulin therapy of diabetic coma (author's transl)].
The experiences of English teams with continuous intravenous infusion of small doses of insulin (6-10 IU/h) for the treatment of diabetic ketoacidosis are reported. This form of therapy is based on recent knowledge of the physiological degree of the serum insulin level (20-200 muU/ml) and the quantity required to saturate the insulin receptors. The advantages of this treatment are in the low therapeutic risk: hypopotassemia, hypoglycemia and cerebral edema, which are disadvantages of conventional therapy of diabetic coma, are avoided.
D001929:Brain Edema / Q000517:prevention & control; D003926:Diabetic Coma / Q000188:drug therapy*; D006801:Humans; D007003:Hypoglycemia / Q000517:prevention & control; D007008:Hypokalemia / Q000517:prevention & control; D007275:Injections, Intravenous / Q000379:methods; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use*
D007328:Insulin
Neue Entwicklungen in der Insulintherapie des diabetischen Koma