Plasma exchange with plasma protein fraction and lactated Ringer's solution using the continuous flow cell separator.
Ten patients underwent 50-70 percent plasma exchanges using the continuous flow cell separator. The exchange material consisted of Plasma Protein Fraction (PPF) and Lactated Ringer's Solution (LRS) instead of fresh frozen, modified or lyophilized plasma. No bleeding or other complications were encountered. The coagulation factor activity after exchange was above that required for hemostasis. The procedure is safe, expeditious and efficient.
D001798:Blood Proteins / Q000008:administration & dosage*; D005078:Exchange Transfusion, Whole Blood / Q000379:methods*; D006402:Hematologic Diseases / Q000628:therapy*; D006501:Hepatic Encephalopathy / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000628:therapy; D010952:Plasma Substitutes / Q000008:administration & dosage*; D008258:Waldenstrom Macroglobulinemia / Q000628:therapy
D001798:Blood Proteins; D010952:Plasma Substitutes