[New researches on protein synthesis inhibition under the action of aurintricarboxylic acid during cell cycle : Study on meristematic cells of Allium sativum L].
Aurin tricarboxylic acid, an inhibitor of protein synthesis, prevents cells from entering mitosis in Allium sativum L. root meristems. When the uptake of 3H-leucine comes back up to the control rate after removal of roots from the drug, mitotoic activity is resumed. Furthermore, the percent of labelled cells obtained by continuous labelling with H3-thymidine shows a reversible arrest of cell progress from G1 to S.
D001312:Aurintricarboxylic Acid / Q000494:pharmacology*; D003509:Cyclohexanecarboxylic Acids / Q000494:pharmacology*; D005737:Garlic; D007930:Leucine / Q000378:metabolism; D008938:Mitosis / Q000187:drug effects*; D010944:Plants / Q000378:metabolism; D010946:Plants, Medicinal; D014176:Protein Biosynthesis; D013936:Thymidine / Q000378:metabolism
D003509:Cyclohexanecarboxylic Acids; D001312:Aurintricarboxylic Acid; D007930:Leucine; D013936:Thymidine
Nouvelles recherches sur l'inhibition des synthèse protéiques sous l'action de l'acide aurine tricarboxylique au cours du cycle cellulaire : étude sur cellules méristématiques d'Allium sativum L