A homologue of the rabbit kappa-chain allotype b9 ON IgG from a cottontail rabbit.
Eight out of 12 anti-b9 antisera tested strongly bound 125IgG of only one of four individual cottontail rabbits (Sylvilagus floridanus). In addition to this apparent polymorphism of a b9 homologue in cottontail rabbits, a polymorphism defined by some anti-b5 antisera was found. Three of 15 anti-b5 antisera reacted with IgG from only two of the four cottontail rabbits. Reactions with anti-b4 and anti-b6 were similar to those with hare IgG. Most anti-b4 and anti-b6 antisera bound the IgG from each animal. The cottontails we tested also resembled the hare with respect to their weak reactivity with some anti-a2 antisera (Vh allotype) and strong reactivity with anti-15 (an allotype localized in the Fc portion of rabbit gamma-chains).
D000818:Animals; D000937:Antigen-Antibody Reactions; D003429:Cross Reactions; D007106:Immune Sera; D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D007519:Isoantigens; D007793:Lagomorpha; D011110:Polymorphism, Genetic; D011817:Rabbits; D013045:Species Specificity
D007106:Immune Sera; D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D007519:Isoantigens