Monoclonal IgM immunoglobulinemia in psoriatic arthritis.
Serum protein electrophoresis in a 61-year-old woman with psoriasis and psoriatic arthritis showed a monoclonal spike that was identified as IgM-kappa monoclonal immunoglobulinemia by immunodiffusion and immunoelectrophoresis. There was no clinical evidence of myeloma, Waldenström macroglobulinemia, or lymphoma, and the M component has not changed over a three-year observation period. This unusual occurrence may represent another disease entity that may be associated with nonmyelomatous monoclonal immunoglobulinemia.
D000367:Age Factors; D001168:Arthritis / Q000276:immunology*; D001797:Blood Protein Electrophoresis; D001799:Blood Sedimentation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007075:Immunoglobulin M / Q000032:analysis*; D008875:Middle Aged; D011565:Psoriasis / Q000276:immunology*
D007075:Immunoglobulin M