Paracetamol-induced hepatic necrosis in the mouse-relationship between covalent binding, hepatic glutathione depletion and the protective effect of alpha-mercaptopropionylglycine.
D000082:Acetaminophen / Q000378:metabolism / Q000494:pharmacology* / Q000652:urine; D000603:Amino Acids, Sulfur / Q000627:therapeutic use*; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000378:metabolism* / Q000517:prevention & control; D005978:Glutathione / Q000378:metabolism*; D008099:Liver / Q000033:anatomy & histology; D008297:Male; D051379:Mice; D013997:Time Factors; D008625:Tiopronin / Q000627:therapeutic use*
D000603:Amino Acids, Sulfur; D000082:Acetaminophen; D008625:Tiopronin; D005978:Glutathione