title: [Relations between catabolite repression and sporulation in Bacillus subtilis (author's transl)].
abstract: Acetoin dehydrogenase can be catabolite repressed by numerous sources of carbon. The following results point out that the catabolite repression of this enzyme and the inhibition of sporulation are mediated by the same mechanism: 1. Mutants, able to synthesize acetoin dehydrogenase in the presence of glucose, sporulate in glucose medium at a higher rate than the standard strain. 2. The catabolite repressing effect of a compound and its ability to inhibit sporulation are in a direct relation to each other. 3. The limitation of inorganic phosphate in the growth medium, which is known to favour sporulation, counteracts the catabolite repressing effect of glucose.
mesh_terms: D000094:Acetoin Dehydrogenase / Q000378:metabolism*; D000429:Alcohol Oxidoreductases / Q000378:metabolism*; D001412:Bacillus subtilis / Q000201:enzymology* / Q000254:growth & development; D004794:Enzyme Repression; D005947:Glucose / Q000494:pharmacology; D009154:Mutation; D010710:Phosphates / Q000494:pharmacology; D013171:Spores, Bacterial / Q000187:drug effects / Q000254:growth & development
chemical_list: D010710:Phosphates; D000429:Alcohol Oxidoreductases; D000094:Acetoin Dehydrogenase; D005947:Glucose
vernacular_title: Beziehungen zwischen katabolischer Repression und Sporulation bei Bacillus subtilis