title: Rifampin resistance mutation of Bacillus subtilis altering the electrophoretic mobility of the beta subunit of ribonucleic acid polymerase.
abstract: The rifampin-resistance mutation of LS3,an asporogenous mutant of Bacillus subtilis 3610, leads to altered mobility of the beta subunit of ribonucleic acid polymerase in sodium dodecyl sulfate-polyacrylamide slab gel electrophoresis. This finding argues that the rifampin-resistance mutation is located in the structural gene coding for the beta polypeptide.
mesh_terms: D001412:Bacillus subtilis / Q000187:drug effects / Q000201:enzymology* / Q000254:growth & development; D012321:DNA-Directed RNA Polymerases / Q000032:analysis; D004352:Drug Resistance, Microbial; D004591:Electrophoresis, Polyacrylamide Gel; D005796:Genes; D009154:Mutation; D010455:Peptides / Q000032:analysis; D010641:Phenotype; D012293:Rifampin / Q000494:pharmacology*; D013171:Spores, Bacterial / Q000254:growth & development; D014170:Transformation, Genetic
chemical_list: D010455:Peptides; D012321:DNA-Directed RNA Polymerases; D012293:Rifampin