[Improvement of memory by post-experiment BALB/c mouse lateral hypothalamus stimulation].
In order to test the influence of a post-trial low level rewarding stimulation on learning, BALB/c mice were bilaterally implanted in the lateral hypothalamus. First, all the animals were submitted to a 15 mn appetitive learning session in a Skinner Box (CRF). 30 s later, animals of the experimental group were stimulated for 80 s (100 Hz sinusoidal current; 200 ms ON/200 ms OFF; 10 muA/electrode). 24 h later the performances of the stimulated animals were compared to those of non-stimulated or not implanted animals. An improvement of reminiscence effect was observed in stimulated animals. Second, the self-stimulation behavior was studied in stimulated subjects; at 10 muA, this behavior was effective in all animals. The results are interpreted as revealing the involvement of the rewarding system in memory processes.
D000818:Animals; D004558:Electric Stimulation; D007031:Hypothalamus / Q000502:physiology*; D008297:Male; D008568:Memory / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D012153:Retention, Psychology / Q000502:physiology*; D012653:Self Stimulation
Amélioration de la réminiscence par stimulation postessai de l'hypothalamus latéral chez la souris BALB/c