N-terminal amino acid sequence of a human delta-chain myeloma protein.
The N-terminal amino acid sequence (26 residues) of a delta-chain of a human myeloma (Er I) is homologous with the prototype sequence of the human VHIII subgroup. This indicates that the delta-chain is using for its V region the same pool of V genes as the rest of the immunoglobulin classes. Implications of this finding are discussed.
D000595:Amino Acid Sequence; D001666:Binding Sites, Antibody; D005796:Genes; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000032:analysis*; D007135:Immunoglobulin Variable Region; D007138:Immunoglobulin delta-Chains / Q000032:analysis*; D009194:Myeloma Proteins
D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region; D007138:Immunoglobulin delta-Chains; D009194:Myeloma Proteins