title: [Influence of chloride ions on the kinetic parameters of rat brain choline acetyltransferase].
abstract: Kinetic properties of Rat brain choline acetyltransferase were studied. Chloride ions promoted the increase of the Km values for the two substrates. Vmax was increased sixty times when chloride ions concentration was elevated from 4.6 to 291 mM.
mesh_terms: D000109:Acetylcholine / Q000096:biosynthesis; D000123:Acetyltransferases / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000201:enzymology; D002712:Chlorides / Q000494:pharmacology*; D002795:Choline O-Acetyltransferase / Q000378:metabolism*; D007700:Kinetics; D051381:Rats
chemical_list: D002712:Chlorides; D000123:Acetyltransferases; D002795:Choline O-Acetyltransferase; D000109:Acetylcholine
vernacular_title: Influence des ions chlore sur les paramètres cinétiques de la choline acétyltransférase du cerveau de rat