Studies on interrelations between eosinophilia, serum IgE and tissue mast cells.
In an examination of a variety of diseases associated with a peripheral blood eosinophilia it is evident that the eosinophilia is not necessarily accompanied by increased amounts of serum IgE. Tissue eosinophilia occurring with mast cell hyperplasia and usually increased amounts of IgE, indicate atopic allergy. It is considered that the eosinophilic granuloma of soft tissue (Kimura's disease) is an atopic disease and quite different from histiocytosis X.
D000038:Abscess / Q000276:immunology; D000818:Animals; D004802:Eosinophilia / Q000276:immunology*; D004803:Eosinophilic Granuloma / Q000276:immunology; D004804:Eosinophils; D005260:Female; D007106:Immune Sera; D005779:Immunodiffusion; D007073:Immunoglobulin E / Q000032:analysis*; D007457:Iodine Radioisotopes; D007958:Leukocyte Count; D008206:Lymphatic Diseases / Q000276:immunology; D008407:Mast Cells / Q000276:immunology*; D011817:Rabbits / Q000276:immunology; D012532:Scabies / Q000276:immunology; D013274:Stomach Neoplasms / Q000276:immunology; D013919:Thromboangiitis Obliterans / Q000276:immunology; D014594:Uterine Neoplasms / Q000276:immunology
D007106:Immune Sera; D007457:Iodine Radioisotopes; D007073:Immunoglobulin E