[Interferon induction in monkeys by poly I-C complex with poly-L-lysine].
The spectrum characteristics, the stability to pancreatic RN-ase and hydrolases of the monkey and mouse blood as well as interferon induction in mice and monkeys by poly I: poly C and its complex with poly-l-lysine were studied. The complex was found to be more stable to the treatments tested as well as markedly interferonogenically active in Macaca rhesus monkeys.
D000818:Animals; D004355:Drug Stability; D000882:Haplorhini; D006867:Hydrolases / Q000378:metabolism; D007369:Interferon Inducers; D007372:Interferons / Q000097:blood*; D008253:Macaca mulatta; D051379:Mice; D010455:Peptides / Q000494:pharmacology*; D011070:Poly I-C / Q000378:metabolism / Q000494:pharmacology*; D011107:Polylysine / Q000494:pharmacology*; D012260:Ribonucleases / Q000378:metabolism
D007369:Interferon Inducers; D010455:Peptides; D011107:Polylysine; D007372:Interferons; D006867:Hydrolases; D012260:Ribonucleases; D011070:Poly I-C
Induktsiia interferona u obez'ian kompleksom poly(I)-poli(Ts) s poli-L-lizinom