Sheehan's syndrome with complete bone marrow aplasia: long-term results of substitution therapy with hormones.
A case of Sheehan's syndrome with pancytopenia and bone marrow aplasia is presented. The diagnosis was made 6 years after an ante-partum haemorrhage. The presenting feature was an anaemia unresponsive to usual therapy. Hormonal therapy alone (cortisone and thyroid extract with triiodothyronin, oestrogen and progestogen given sequentially) produced full haematological recovery, which has continued for 2 years since the treatment was begun.
D000328:Adult; D001855:Bone Marrow Diseases / Q000150:complications* / Q000188:drug therapy; D003348:Cortisone / Q000627:therapeutic use*; D004967:Estrogens / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007018:Hypopituitarism / Q000150:complications* / Q000188:drug therapy; D008134:Long-Term Care; D010198:Pancytopenia / Q000150:complications* / Q000188:drug therapy; D011372:Progestins / Q000627:therapeutic use*; D013963:Thyroid Hormones / Q000627:therapeutic use*
D004967:Estrogens; D011372:Progestins; D013963:Thyroid Hormones; D003348:Cortisone