Similarities among hypervariable segments of immunoglobulin chains.
A human lambdaV (Mcg) and a human lambdaII (Vil) myeloma protein have identical sequences in their first hypervariable segments although they differ at 21 positions throughout the variable region. If a different structural gene is responsible for each subgroup, the findings favor insertion of information for the hypervariable or complementarity-determining segments.
D000595:Amino Acid Sequence; D014644:Genetic Variation; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000032:analysis*; D009194:Myeloma Proteins / Q000032:analysis*
D007147:Immunoglobulin Light Chains; D009194:Myeloma Proteins