Intraocular irrigating solutions and lens clarity.
By in vitro incubation of rhesus monkey lenses at 37degreesC, we determined that solutions superior to intraocular irrigating solutions in common clinical use could be prepared by aspetically adding commerically available solutions of dextrose 5% in water and sodium bicarbonate to either Ringer's injection or Ringer's lactate solutions. While not as effective as glutathione-bicarbonate-Ringer's solution (G-B-R) in maintaining lens clarity, these mixtures can be prepared easily in the operating room (in contrast to G-B-r) and may improve surgical results in procedures requiring prolonged intraocular irrigation.
D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology; D002386:Cataract / Q000139:chemically induced; D005978:Glutathione / Q000494:pharmacology; D000882:Haplorhini; D007552:Isotonic Solutions; D007773:Lactates / Q000009:adverse effects; D007908:Lens, Crystalline; D008253:Macaca mulatta; D009883:Ophthalmic Solutions; D007507:Therapeutic Irrigation
D001639:Bicarbonates; D007552:Isotonic Solutions; D007773:Lactates; D009883:Ophthalmic Solutions; D005978:Glutathione