A gamma Bence-Jones protein in guinea pigs.
1. The L2C lymphocytic leukaemia in strain-2 guinea pigs is accompanied by a protein in the urine resembling a homogenous immunoglobulin light chain. 2. The amino acid sequence over the first 20 residues demonstrates a close analogy with a human gamma chain of V region subgroup IV. 3. The protein is apparently synthesized by the leukaemic cells and thus represents a monoclonal light chain, i.e. a Bence-Jones protein.
D000595:Amino Acid Sequence; D000818:Animals; D001536:Bence Jones Protein / Q000032:analysis* / Q000652:urine; D002852:Chromatography, Ion Exchange; D004591:Electrophoresis, Polyacrylamide Gel; D006168:Guinea Pigs; D005779:Immunodiffusion; D007146:Immunoglobulin lambda-Chains; D007945:Leukemia, Lymphoid / Q000652:urine
D007146:Immunoglobulin lambda-Chains; D001536:Bence Jones Protein