The effect of sodium cromoglycate on the antigen-induced nasal reaction in allergic rhinitis as measured by rhinomanometry and symptomatology.
The protective effect of sodium cromoglycate (DSCG) on the allergic reaction in the nose was compared with placebo in a double blind crossover study of sixteen patients diagnosed as allergic rhinitis. The drug effect was assessed by both a rhinomanometric method and by symptom scores in all patients. DSCG protected the nasal mucosa against antigen challenge and was significantly better than placebo. There was a correlation betwen the objective and subjective assessments.
D000293:Adolescent; D000328:Adult; D000403:Airway Resistance / Q000187:drug effects; D000941:Antigens; D004205:Cromolyn Sodium / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D009666:Nose; D010919:Placebos; D006255:Rhinitis, Allergic, Seasonal / Q000175:diagnosis / Q000188:drug therapy*
D000941:Antigens; D010919:Placebos; D004205:Cromolyn Sodium