[Chronic infection of VERO cell cultures with Japanese encephalitis virus. 2. Certain characteristics of variability of persistent viruses].
Japanese encephalitis virus contained in the medium of chronically infected VERO-K43 cell cultures was shown to be sensitive to the effect of RNA-ase, resistant to treatment with urea, to have no hemagglutinating activity. After 2 passages in suckling mouse brain the virus lost its sensitivity to RNA-ase, was inactivated by urea, and its hemagglutinating activity was restored. The importance of Japanese encephalitis virus variability in the mechanism of chronic infection of cell cultures is discussed.
D000818:Animals; D004352:Drug Resistance, Microbial; D014644:Genetic Variation; D000882:Haplorhini; D006389:Hemagglutinins, Viral; D007668:Kidney; D012260:Ribonucleases / Q000494:pharmacology; D014508:Urea / Q000494:pharmacology
D006389:Hemagglutinins, Viral; D014508:Urea; D012260:Ribonucleases
Khronicheskaia infektsiia kul'tur kletok VERO virusom iaponskogo entsefalita. Soobshchenie 2. Nekotorye osobennosti izmenchinosti persistiruiushchego virusa