The effects of vitamine C on lipid metabolism.
Evidence is presented showing that vitamin C had definite effects on lipid metabolism. The stress of captivity on free-living baboons causes a decrease in serum vitamin C levels and an increase in serum cholesterol levels. Increased dietary intake of vitamin C during the initial stages of captivity significantly decreases the serum cholesterol values. Dietary vitamin C stimulates the synthesis of cholesterol from 14C-labelled acetate and mevalonate in baboon liver homogenates and increases the turnover rate of the cholesterol body pool. Vitamin C inhibits baboon cardiac lipoprotein lipase activity.
D000085:Acetates / Q000378:metabolism; D000818:Animals; D001205:Ascorbic Acid / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D002784:Cholesterol / Q000096:biosynthesis / Q000097:blood; D000882:Haplorhini; D006801:Humans; D050356:Lipid Metabolism; D008071:Lipoprotein Lipase / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008798:Mevalonic Acid / Q000378:metabolism; D009206:Myocardium / Q000201:enzymology; D010215:Papio; D012621:Seasons; D013315:Stress, Psychological
D000085:Acetates; D002784:Cholesterol; D008071:Lipoprotein Lipase; D001205:Ascorbic Acid; D008798:Mevalonic Acid