Effect of sodium cromoglycate on asthmatic reactions to environmental temperature changes.
Immediate asthmatic reactions, with falls in FEV1 of 16-42.5% were elicited by exposure in a cold room at 3 degrees C in five out of eight subjects with histories of asthma provoked by falls in environmental temperature. In four of the subjects pretreatment by inhalation of sodium cromoglycate gave complete inhibition of the asthmatic reaction in two, partial inhibition in one and had no effect in one case.
D000281:Administration, Intranasal; D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000008:administration & dosage; D001249:Asthma / Q000188:drug therapy*; D003080:Cold Temperature; D003371:Cough / Q000209:etiology; D004205:Cromolyn Sodium / Q000008:administration & dosage*; D004417:Dyspnea / Q000209:etiology; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008875:Middle Aged; D012882:Skin Tests; D013997:Time Factors
D000485:Allergens; D004205:Cromolyn Sodium