Oxidation of selenocystamine by diamineoxidase.
Selenocystamine is oxidatively deaminated by pig kidney diamineoxidase. The first product of the reaction is the corresponding cyclized aminoaldehyde, selenocystaldimine, which then undergoes further degradation. The oxidative deamination is thus the first step of a series of cyclic reactions which give rise to extensive cleavage of selenocystamine.
D006631:Amine Oxidase (Copper-Containing) / Q000378:metabolism*; D000818:Animals; D003538:Cystamine / Q000031:analogs & derivatives* / Q000378:metabolism; D007097:Imines / Q000378:metabolism; D007461:Iodoacetates / Q000494:pharmacology; D007668:Kidney / Q000201:enzymology; D016566:Organoselenium Compounds; D010101:Oxygen Consumption; D012643:Selenium / Q000378:metabolism; D013552:Swine
D007097:Imines; D007461:Iodoacetates; D016566:Organoselenium Compounds; C014807:selenocystamine; C014806:selenocystaldimine; D006631:Amine Oxidase (Copper-Containing); D012643:Selenium; D003538:Cystamine