title: [Occurrence and function of a proteinase inhibitor in the hemolymph of insects].
abstract: The presence of proteinase inhibitor has been proved in the hemolymph of a number of insect species from seven different insect orders. The amount of proteinase inhibitor in the hemolymph significantly increases after injection of inactivated bacteria into the hemocoelom of Galleria mellonella-larvae. Moreover the larvae show an increased resistance against normally lethal concentrations of trypsin, chymotrypsin, pronase P and extracellular proteinase produced by Pseudomonas aeruginosa. It is discussed that the proteinase inhibitor is one of the factors acting in the antibacterial defense system in the hemolymph of Galleria mellonella-larvae.
mesh_terms: D000818:Animals; D001409:Bacillus cereus / Q000201:enzymology; D002918:Chymotrypsin; D004791:Enzyme Inhibitors / Q000032:analysis*; D006458:Hemolymph / Q000032:analysis*; D005779:Immunodiffusion; D007313:Insecta; D010206:Papain; D010447:Peptide Hydrolases; D011402:Pronase; D011514:Proteus vulgaris / Q000201:enzymology; D011550:Pseudomonas aeruginosa / Q000201:enzymology; D012706:Serratia marcescens / Q000201:enzymology; D013305:Streptomyces griseus / Q000201:enzymology; D014357:Trypsin
chemical_list: D004791:Enzyme Inhibitors; D010447:Peptide Hydrolases; D002918:Chymotrypsin; D014357:Trypsin; D010206:Papain; D011402:Pronase
vernacular_title: Untersuchungen zum Vorkommen und zur Funktion eines Proteinaseninhibitors in der Hämolymphe von Insekten