Immunodeficiency and infantile bone and joint infection.
Fifteen patients with infantile bone and joint infections were studied immunologically and clinically, 3 at the time of illness and 12 later. Abnormality of immunoglobulins, or complement, or phagocytes was found in 9 patients; 6 were within normal limits for the tests undertaken. Immunodeficiency is probably responsible for the subdued clinical signs of infection and for delayed diagnosis in some patients. It was also related to the extent of femoral head damage in infective arthritis of the hip and to the incidence of wound infection in late elective surgery.
D000293:Adolescent; D000328:Adult; D000373:Agglutinins / Q000032:analysis; D001170:Arthritis, Infectious / Q000276:immunology; D001772:Blood Cell Count; D001847:Bone Diseases / Q000000981:diagnostic imaging / Q000276:immunology* / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D003165:Complement System Proteins / Q000032:analysis; D005260:Female; D006615:Hip / Q000601:surgery; D006801:Humans; D005779:Immunodiffusion; D007136:Immunoglobulins / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000150:complications*; D007223:Infant; D007518:Isoantibodies / Q000032:analysis; D007592:Joint Diseases / Q000000981:diagnostic imaging / Q000276:immunology* / Q000382:microbiology; D007709:Klebsiella / Q000302:isolation & purification; D008297:Male; D010019:Osteomyelitis / Q000276:immunology; D010587:Phagocytosis; D011446:Prospective Studies; D011859:Radiography; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000276:immunology*; D013210:Staphylococcus / Q000302:isolation & purification
D000373:Agglutinins; D007136:Immunoglobulins; D007518:Isoantibodies; D003165:Complement System Proteins