[Involvement of the spleen in congenital osteopetrosis of the "op" rat: corrective effect of thymus grafts].
In the osteopetrotic mutant rat "op", the white pulp of the spleen is poor in T lymphocytes, while the red pulp is hyperplastic in reaction to the aplastic bone marrow. Grafting of normal thymus into the mutant corrects these anomalies.
D000818:Animals; D005808:Genes, Recessive; D010022:Osteopetrosis / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D051381:Rats; D013154:Spleen / Q000473:pathology*; D013950:Thymus Gland / Q000637:transplantation*; D014184:Transplantation, Homologous
Atteinte de la rate dans l'ostéopétrose congénitale du rat "op": effet curatif de la greffe de thymus