[The type specific antigen of Gross leukemia virus in tumors and normal tissues and its identification by immunodiffusion methods].
A monospecific antiserum for type-specific antigen of Gross virus (AGLV) was obtained. Tumours of different origin were studied with this monospecific antiserum in the gel-diffusion test. AGLV was revealed in spontaneous kidney tumour of CC57BR mice, and in chemically (carcinogen)- induced tumours of mice. These findings suggest activation of MuLV viral genom in low-leukemic strains of mice.
D015127:9,10-Dimethyl-1,2-benzanthracene; D000406:AKR murine leukemia virus / Q000276:immunology*; D000818:Animals; D000956:Antigens, Viral; D007942:Leukemia, Experimental / Q000276:immunology; D007951:Leukemia, Myeloid / Q000139:chemically induced; D008223:Lymphoma / Q000276:immunology; D008228:Lymphoma, Non-Hodgkin / Q000276:immunology; D008748:Methylcholanthrene; D051379:Mice; D008806:Mice, Inbred AKR; D008815:Mice, Inbred Strains; D009374:Neoplasms, Experimental / Q000276:immunology*; D012509:Sarcoma / Q000139:chemically induced
D000956:Antigens, Viral; D008748:Methylcholanthrene; D015127:9,10-Dimethyl-1,2-benzanthracene
Tipospetsificheskiĭ antigen virusa leĭkemii Grossa v opukholiakh i normal'nykh tkaniakh i ego identifikatsiia metodami immunodiffuzii