Histopathological and histochemical studies on the tonsils in children with rheumatic heart disease.
The tonsils were studied histologically and histochemically in 67 children with rheumatic heart disease, 33 children with chronic tonsillitis and 5 normal children. The tonsils of rheumatic children showed hyperplasia and hyperactivity of lymphocytes and paucity of phagocytes. It was suggested that these peculiar findings might contribute to the pathogenesis of rheumatic fever.
D000135:Acid Phosphatase / Q000378:metabolism; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004950:Esterases / Q000378:metabolism*; D006651:Histocytochemistry; D006801:Humans; D006965:Hyperplasia; D008214:Lymphocytes / Q000378:metabolism; D014066:Palatine Tonsil / Q000201:enzymology* / Q000473:pathology; D010586:Phagocytes / Q000378:metabolism; D012213:Rheumatic Fever / Q000209:etiology; D012214:Rheumatic Heart Disease / Q000201:enzymology* / Q000473:pathology; D013385:Succinate Dehydrogenase / Q000378:metabolism*; D014069:Tonsillitis / Q000201:enzymology / Q000473:pathology
D013385:Succinate Dehydrogenase; D004950:Esterases; D000135:Acid Phosphatase