[The sheep OL lymphocyte antigen system: 11 factors detected by microcytotoxicity assays in a prealp flock].
By means of microcytotoxicity techniques and using 9 immune allosera, 11 lymphocyte factors were determined in Prealpe sheep, 10 factors, transmitted by haplotypes, depended genetically on 2 linked locus: OL-A and OL-B. From a sample of 130 haplotypes, 36 OL-A alleles were demonstrated by 6 combinations of 1 to 2 factors and 80 OL-B alleles by 32 combinations of 1 to 5 factors. Genic frequencies were varied and low: inferior to 0,01 for half of the combinations they only once exceeded 0,1. The overall frequency of marked genes was estimated to 0,27 for OL-A and 0,61 for OL-B. The genetic transmission of the 11th factor (frequency: 0,05) depended on a 3rd OL-C locus of the same system.
D000483:Alleles; D000818:Animals; D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D005838:Genotype; D007126:Immunoglobulin Allotypes / Q000145:classification; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D012756:Sheep / Q000276:immunology*
D007126:Immunoglobulin Allotypes
Le système d'antigènes lymphocytaires OL du mouton. Etude, dans un troupeau de race préalpe, de onze facteurs décelés par microcytotoxicité