title: Relation between macrophage migration inhibition and immunity to Brucella abortus in guinea-pigs.
abstract: Relation between macrophage migration inhibition and immunity to Brucella abortus in guinea-pigs. Onderstepoort Journal of Veterinary Research 43 (4), 175-184 (1976). A soluble protein antigen was prepared from Brucella melitensis Rev I with which macrophage migration inhibition (MMI) assays were successfully done using guinea-pig peritoneal exudate cells. By comparing the MMI, agglutinin response and immunity of groups and of individual guinea-pigs which had been immunized with either B. melitensis Rev I live vaccine or B. melitensis Rev I inactivated antigen, an association between the MMI and resistance to infection was demonstrated.
mesh_terms: D000367:Age Factors; D000373:Agglutinins / Q000032:analysis; D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D000942:Antigens, Bacterial; D002002:Brucella / Q000276:immunology; D002004:Brucella Vaccine; D002003:Brucella abortus / Q000276:immunology*; D002464:Cell Migration Inhibition; D006168:Guinea Pigs; D007111:Immunity, Cellular; D008264:Macrophages / Q000276:immunology*
chemical_list: D000373:Agglutinins; D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D002004:Brucella Vaccine