title: [Mouse brain gangliosides during development: demonstration of a new ganglioside].
abstract: The study of gangliosides as a function of age indicates that four of the main components GD1a (G3), GD1b (G2), GT1 (G1) and GQ (G0) are present at birth. They increase with age. On thin-layer chromatography, GD1a seems to be maximum at 18 days and GD1b continues to increase. GM1 increases also from birth to adult age. A new ganglioside has been detected in Mouse brain during its development. Not detected 5 days after birth, it is present at 18 days and in maximal quantity at adult age. This compound does not seem to be correlated to myelination process.
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000254:growth & development; D001923:Brain Chemistry; D005732:Gangliosides / Q000032:analysis*; D051379:Mice; D008810:Mice, Inbred C57BL
chemical_list: D005732:Gangliosides
vernacular_title: Etude des gangliosides dans le cerveau de souris au cours de sa maturation: mise en évidence d'un nolveau ganglioside