title: [The effect of neuraminidase of C. diphtheriae on the functional capacity of the peritoneal exudate cells of guinea pigs to diphtheria bacilli].
abstract: A study was made of the effect of neuraminidase preparation containing no diphtheria toxin admixtures and hyaluronidase on the phagocytic activity of macrophages. Neuraminidase produced a stimulating effect on the cells of the developing macrophage culture. The macrophages treated with the enzyme increased their capacity to digestion of nontoxigenic diphtheria bacilli.
mesh_terms: D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D002478:Cells, Cultured; D003353:Corynebacterium diphtheriae / Q000201:enzymology / Q000276:immunology*; D006168:Guinea Pigs; D006821:Hyaluronoglucosaminidase / Q000494:pharmacology; D008264:Macrophages / Q000187:drug effects / Q000276:immunology*; D009439:Neuraminidase / Q000494:pharmacology*; D010587:Phagocytosis / Q000187:drug effects*
chemical_list: D009439:Neuraminidase; D006821:Hyaluronoglucosaminidase
vernacular_title: Izuchenie vliianiia neiraminidazy C. diphtheriae na funktsional'nuiu sposobnost' kletok peritoneal'nogo ekssudata morskikh svinok po otnosheniiu k difteriinym bakteriiam