[Evaluation of successful chemotherapie of infections of the urinary system by determination of antibacterial activity in the urine (author's transl)].
5,589 urin samples from patients with suspected infections of the urinary tract were screened for inhibiting activity against Baz. cereus (ATCC 6051). In 19% of these urines such inhibitors could be found. In spite of the antibacterial inhibition activity nearly half of the samples had bacteria in high number. By comparison of the various bacterial species in both groups of urin, in those without antibacterial "Problem-Bacteria": Klebsiella-Enterobacter- Proteus- Candida-species is demonstrated. If one compares the urine of the same patient before and under chemotherapie it seems as if antibiotic therapie is often started without proof of significant bacteriuria. In those patients, where there was a significant bacteriuria in the first urine sample only 7 from 20 showed sterile urine under chemotherapie; 10 patients had an other species in the second sample and 3 patients had the same species isolated from urine during therapie. The diagnosis and the consequences especially for therapie in stationary patients with recurrent infections is discussed.
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use / Q000652:urine*; D001409:Bacillus cereus / Q000187:drug effects; D001419:Bacteria / Q000302:isolation & purification; D002176:Candida albicans / Q000302:isolation & purification; D006801:Humans; D013045:Species Specificity; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000652:urine; D014556:Urine / Q000382:microbiology
D000900:Anti-Bacterial Agents
Erfolgsbeurteilung der Chemotherapie bei Harnweginfektionen anhand von Hemmonstoffnachweis im Urin