title: Relative genetic efficiency of 50 Me V protons as derived from analyses of chromosome anomalies in human lymphocytes.
abstract: Based on quantitation of chromosome anomalies observed following in vitro irradiations of human lymphocytes, RGE values were derived for 50 Me V protons relative to 180 kV X-rays.  These values indicated 50 Mc V protons to be generally of similar efficiency as X-rays in producing chromosome anomalies in human lymphocytes.  However, detailed analysis by types of anomalies observed yielded different RGE values.  Thus, 50 Me V protons were found to be 15 percent less efficient than X-rays in producing two-break exchange type aberrations.  And inversely, they were about 15 percent more efficient in producing onebread types of aberrations.
mesh_terms: D002869:Chromosome Aberrations; D002875:Chromosomes / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects; D008962:Models, Theoretical; D011522:Protons; D011831:Radiation Genetics; D011882:Radiotherapy, High-Energy
chemical_list: D011522:Protons