title: Is there a gene regulating the scute locus on the third chromosome of D. melanogaster?
abstract: A section of the third chromosome of D. melanogaster some 25 to 40 centimorgans long including sr was transferred from a wild-type stock selected by Latter for high scutellar bristle number into a scute stock with a large number of scutellar bristles. This segment is shown to have a large effect on the bristle numbers of wild-type flies, to reduce the strength of canalization of the scute phenotype at 4 bristles, to have little, if any, effect on bristle numbers of scute flies with less that 4 bristles but to increase the number of flies with 5 and 6 scutellar bristles in scute stocks that normally have a large number of flies with 4 bristles. It is suggested that this segment in unselected chromosomes contains a gene that regulates bristle number by repressing the scute locus and that Latter has selected a mutant of the regulator which fails to repress the aciton of the scute locus.
mesh_terms: D000818:Animals; D002875:Chromosomes; D003433:Crosses, Genetic; D004331:Drosophila melanogaster; D005260:Female; D005809:Genes, Regulator; D006197:Hair; D008297:Male; D009154:Mutation; D010641:Phenotype