Abortifacient effects of prostaglandin E2 in the pigtailed macaque (Macaca nemestrina).
15(S)15-methyl-prostaglandin E2 was evaluated for abortifacient effects at various stages of pregnancy in five Macaca nemestrina. Despite its reported effectiveness in inducing abortions in human beings, it was concluded that this compound is not appropriate for collecting fetal material of known gestational age for morphologic and histologic examinations.
D000028:Abortion, Induced / Q000662:veterinary*; D000818:Animals; D036861:Delivery, Obstetric; D005260:Female; D005865:Gestational Age; D000882:Haplorhini; D007273:Injections, Intramuscular; D008251:Macaca / Q000502:physiology*; D011247:Pregnancy; D011458:Prostaglandins E / Q000008:administration & dosage / Q000494:pharmacology*; D011459:Prostaglandins E, Synthetic / Q000494:pharmacology*; D014590:Uterine Contraction / Q000187:drug effects
D011458:Prostaglandins E; D011459:Prostaglandins E, Synthetic