[Treatment of atypical absences with a combination of succinimide and dipropylacetate (author's transl)].
Fifteen epileptic patients with mild seizures of the narcolepsy type were treated with a combination of succinimide (average dose 750 mg) and dipropylacetate (average dose 1,200 mg), medication with each drug alone having brought no success. The combination of drugs stopped the seizures in eleven patients, in three they almost stopped and in one the frequency of seizures was halved. An E.E.G. was recorded in twelve, with improvement in each. Side effects occurred in five patients (nausea, vomiting, singultus and fatigue), but the drug had to be discontinued in only one instance.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D004832:Epilepsy, Absence / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012075:Remission, Spontaneous; D013388:Succinimides / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D014631:Valerates / Q000627:therapeutic use*; D014635:Valproic Acid / Q000008:administration & dosage / Q000627:therapeutic use*
D013388:Succinimides; D014631:Valerates; D014635:Valproic Acid
Behandlung atypischer Absencen mit einer Succinimid-Dipropylacetat-Kombination