title: [Preliminary studies on chromatin subunits by freeze-etching].
abstract: We show that freeze-etching electron microscopy preserves and visualizes chromatin structure at level 25 A. Chromatin depleted of histone H 1 is observed to consist of subunits each having a central asymmetric core of DNA and protein 100 by 120 A. Around this core is wound a loop of DNA containing about 130 base pairs and perhaps some protein.
mesh_terms: D000818:Animals; D002417:Cattle; D002843:Chromatin / Q000648:ultrastructure*; D005613:Freeze Etching; D006657:Histones; D008854:Microscopy, Electron; D013950:Thymus Gland / Q000648:ultrastructure
chemical_list: D002843:Chromatin; D006657:Histones
vernacular_title: Etudes préliminaires des sous-unités de la chromatine par cryodécapage