[Toxic properties of the exotoxin from anthrax vaccinal strain CTI-1 in an experiment on animals].
A study of sensitivity of various laboratory animals (guinea pigs, albino mice, Cricetus auratus W., albino rats and chick embryos) demonstrated that they all, excluding the latter, reacted by specific edema in response to the administration of the exotoxin produced by the vaccine strain CTI-1. A quantitative characteristics of the activity of the preparation for albino mice was presented and a method permitting to determine the activity of the anthrax exotoxin in intradermal test on guinea pigs with a greater precision than the accepted one was elaborated.
D000818:Animals; D001408:Bacillus anthracis / Q000276:immunology*; D001428:Bacterial Vaccines; D002642:Chick Embryo; D006224:Cricetinae; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D007928:Lethal Dose 50; D051379:Mice; D011817:Rabbits; D051381:Rats; D013997:Time Factors; D014118:Toxins, Biological / Q000008:administration & dosage / Q000633:toxicity*
D001428:Bacterial Vaccines; D014118:Toxins, Biological
Toksicheskie svoĭstva ékzotoksina sibireiazvennogo vaktsinnogo shtamma CTI-1 v éksperimente na zhivotnykh