Effect of aging on right ventricular anoxic resistance.
Total serum thyroxine levels, saturation of endogenous thyroxine-binding proteins, and free thyroxine indices were all reduced in the rat by aging. In vitro myocardial anoxic resistance was increased as a result of the aging process. The role of myocardial glycogen as a myocardial protective agent during hypoxic stress and its variations during aging, altitude-acclimation, and exericise conditioning are discussed.
D000375:Aging; D000818:Animals; D006003:Glycogen / Q000378:metabolism; D006321:Heart / Q000254:growth & development*; D006352:Heart Ventricles / Q000503:physiopathology*; D000860:Hypoxia / Q000378:metabolism / Q000503:physiopathology*; D008297:Male; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D013974:Thyroxine / Q000097:blood; D013975:Thyroxine-Binding Proteins / Q000378:metabolism
D013975:Thyroxine-Binding Proteins; D006003:Glycogen; D013974:Thyroxine