Comparative study of plasma cortisol evolution in TRH or placebo injected patients with or without thyroid disease.
The plasma cortisol evolution under TRH has been compared in 27 euthyroid, 12 hyperthyroid and 5 patients with hot nodules and in 15 control individuals receiving a placebo or sham injection. The results showed no statistical difference in plasma cortisol evolution between the groups, suggesting no influence of the thyroid status or TSH secretion on the spontaneous fall of cortisol level during the time of the test.
D002986:Clinical Trials as Topic; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D006980:Hyperthyroidism / Q000097:blood*; D007700:Kinetics; D010919:Placebos / Q000494:pharmacology*; D013959:Thyroid Diseases / Q000097:blood; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology*
D010919:Placebos; D013973:Thyrotropin-Releasing Hormone; D006854:Hydrocortisone