[Ultrastructural changes in the organization of plasma membranes in adipocytes of obese mice (ob/ob)].
Freeze-fracture replicas were obtained from adipocytes in control and obese (ob/ob) Mice. Quantitative evaluation of the replicas shows that plasma membranes of adipocytes in ob/ob Mice have 50% less intramembrane particles than plasma membranes in control Mice. Since intra-membrane particles represent, at least in part, the proteins of the membrane, this suggests a decreased protein concentration, as well as a perturbed protein-lipid ratio in adipocyte membranes of obese Mice.
D000273:Adipose Tissue / Q000648:ultrastructure*; D000818:Animals; D002462:Cell Membrane / Q000648:ultrastructure; D004822:Epididymis; D005614:Freeze Fracturing; D008297:Male; D051379:Mice; D008820:Mice, Obese / Q000033:anatomy & histology*; D008854:Microscopy, Electron
Modification ultrastructurale de l'organisation des membranes plasmiques des adipocytes chez les souris obèses (ob/ob)