Immunological response to glomerular basement membrane and streptococcal antigensin immunized rabbits.
Cellular and humoral responses were ivestigated following human glomerular basement membrane a-d streptococcol Type 12 membrane injections in rabbits.  Using the leucocyte migration inhibition test and double diffusion in agar gel, cross-reactivity between the antigens was evident, though neither antigen induced significant proteinuria or nephritis in the dosages given.
D000818:Animals; D000917:Antibody Formation; D000942:Antigens, Bacterial; D001485:Basement Membrane / Q000276:immunology*; D002464:Cell Migration Inhibition; D003429:Cross Reactions; D006801:Humans; D007109:Immunity; D007111:Immunity, Cellular; D005779:Immunodiffusion; D007668:Kidney / Q000276:immunology; D007678:Kidney Glomerulus / Q000276:immunology*; D007962:Leukocytes / Q000276:immunology; D008297:Male; D009393:Nephritis / Q000276:immunology; D011507:Proteinuria / Q000276:immunology; D011817:Rabbits; D013291:Streptococcus / Q000276:immunology*
D000942:Antigens, Bacterial