[The mycotoxin sensitivity of several Bacillus thuringiensis (Berliner) strains sensitive and resistant to aflatoxin B1].
Antimicrobial activity of pure preparations of seven mycotoxins, coumarin and dicoumarin, was studied against various strains of Bacillus thuringiensis (Berliner). The acquisition of resistance to Aflatoxin B1, by a new strain designated "stable variant", obtained in the presence of mycotoxin lethal dose, is very specific. However, a relation seems to exist between Aflatoxin B1 susceptibility and sensitivity to compounds which possess a double furan ring. In vitro, coumarin exhibits an inhibitory effect against antibacterial activity of Aflatoxin B1.
D000348:Aflatoxins / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D001413:Bacillus thuringiensis / Q000187:drug effects*; D003374:Coumarins / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D009183:Mycotoxins / Q000494:pharmacology*; D013045:Species Specificity; D013329:Structure-Activity Relationship
D000348:Aflatoxins; D003374:Coumarins; D009183:Mycotoxins
Sensibilité de souches de Bacillus thuringiensis (Berliner), sensibles et résistantes è l'aflatoxine B1, à quelques mycotoxines