Inhibition of pseudomonas strains in two soft contact lens soaking solutions.
Ten Pseudomonas aeruginosa and six Pseudomonas cepacia strains recently isolated from infected patients were tested for susceptibility to the antimicrobial activity of two commercially-available soft contact lens soaking solutions. No strain showed evidence of viability after two hours but survivors were found in both solutions after one-half hour and in one solution after one hour. The solution most effective in inhibiting the Pseudomonas strains contained chlorhexidine and disodium edetate but each solution was effective in reducing heavy inocula of both species within the times recommended by the manufacturers.
D002710:Chlorhexidine / Q000494:pharmacology; D003263:Contact Lenses, Hydrophilic; D011549:Pseudomonas / Q000187:drug effects / Q000302:isolation & purification*; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000302:isolation & purification; D012996:Solutions; D013997:Time Factors
D012996:Solutions; D002710:Chlorhexidine