Antibody response to Rocky Mountain spotted fever.
Various techniques were compared to determine the most sensitive method for detection of rocky Mountain spotted fever antibody. A radiometabolic technique for detection of Rocky Mountain spotted fever antibody is also described. In infected monkeys, the fluorescent antibody technique yielded the earliest evidence of seroconversion; with some monkeys the microagglutination procedure was equally effective. The fluorescent antibody and microagglutination measurements showed higher titers than those for complement fixation, Weil-Felix, or the radiometabolic techniques.
D000372:Agglutination Tests; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis*; D000917:Antibody Formation; D003168:Complement Fixation Tests; D004195:Disease Models, Animal; D005069:Evaluation Studies as Topic; D005455:Fluorescent Antibody Technique; D000882:Haplorhini; D006801:Humans; D007158:Immunologic Techniques; D008253:Macaca mulatta; D012284:Rickettsia rickettsii / Q000276:immunology*; D012373:Rocky Mountain Spotted Fever / Q000276:immunology*
D000907:Antibodies, Bacterial