Radiobiological studies of a high-energy modulated proton beam utilizing cultured mammalian cells.
The modulated, 160-MeV proton beam produced by the Harvard Cyclotron has been examined in detail for its ability to kill mammalian cells as assayed by colony forming ability. Using two different cell exposure techniques, the characteristics of position and total dose in producing cell death in two aneuploid cell lines selected for their radiobiological relevance have been determined...
D000818:Animals; D002455:Cell Division / Q000528:radiation effects; D002470:Cell Survival / Q000528:radiation effects; D002478:Cells, Cultured / Q000528:radiation effects*; D003037:Cobalt Radioisotopes; D004285:Dogs; D004307:Dose-Response Relationship, Radiation; D000882:Haplorhini; D007928:Lethal Dose 50; D051379:Mice; D011522:Protons; D011817:Rabbits; D051381:Rats
D003037:Cobalt Radioisotopes; D011522:Protons