Specific activities of 6-phosphogluconate dehydrogenase, glucose-6-phosphate dehydrogenase and glucose-6-phosphate isomerase during Bufo bufo development.
It has been suggested by some authors that during amphibian development, due to the higher glucose-6-phosphate dehydrogenase (EC 1.1.1.49) activity compared to that of 6-phosphogluconate dehydrogenase (EC 1.1.1.43), 6-phosphogluconate could accumulate in the embryo tissues and regulate the channelling of glucose-6-phosphate into glycolysis. Here, on the base of the specific activities of glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and glucose-6-phosphate isomerase (EC 5.3.1.9) found in the embryos of Bufo bufo during development, it is discussed whether 6-phosphogluconate can accumulate and play a regulative role on glucose-6-phosphate metabolism in the anuran embryo.
D000818:Animals; D001001:Anura; D002023:Bufo bufo / Q000254:growth & development*; D004625:Embryo, Nonmammalian / Q000378:metabolism; D005956:Glucose-6-Phosphate Isomerase / Q000378:metabolism*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism*; D008675:Metamorphosis, Biological; D010734:Phosphogluconate Dehydrogenase / Q000378:metabolism*
D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D005956:Glucose-6-Phosphate Isomerase