[Experimental polymyositis induced by the injection of acetylcholine receptors. Study of the lesions in rats and guinea pigs].
The injection of acetylcholine receptors, from the Electrophorus electricus induces in Guinea Pigs and Rats an experimental disease, which is characterized by the appearance of antibodies to sarcolemma and by massive histological alterations of the degenerative type, similar to those observed in clinical polymyositis.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D003964:Diaphragm / Q000473:pathology; D004195:Disease Models, Animal; D006168:Guinea Pigs; D009132:Muscles / Q000473:pathology; D009220:Myositis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D051381:Rats; D011950:Receptors, Cholinergic; D012508:Sarcolemma / Q000276:immunology
D000906:Antibodies; D011950:Receptors, Cholinergic
Polymyosite expérimentale provoquée par l'injection de récepteurs d'acétylcholine. Etude des lésions chez le rat et chez le cobaye