title: Nervous system involvement in malignant tumours of the nose and paranasal sinuses.
abstract: One hundred and eighty-three cases with malignant tumours of the nose and paranasal sinuses have been studied retrospectively. Sixty-eight showed evidence of involvement of the central nervous system based on clinical findings, X-rays and findings on operation or autopsy. Among these, in thirty-six there was direct extension of the tumour through the base of the skull, commonly into the anterior cranial fossa. In seven there were metastatic deposits in the cranial bones. Twenty-seven presented with clinical features suggestive of involvement of the central nervous system.
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging; D001932:Brain Neoplasms / Q000000981:diagnostic imaging; D002277:Carcinoma / Q000000981:diagnostic imaging; D002295:Carcinoma, Transitional Cell / Q000000981:diagnostic imaging; D003390:Cranial Nerve Neoplasms / Q000000981:diagnostic imaging; D005134:Eye Neoplasms / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009669:Nose Neoplasms / Q000000981:diagnostic imaging; D010255:Paranasal Sinus Neoplasms / Q000000981:diagnostic imaging; D010954:Plasmacytoma / Q000000981:diagnostic imaging; D011859:Radiography; D012509:Sarcoma / Q000000981:diagnostic imaging; D012888:Skull Neoplasms / Q000000981:diagnostic imaging