title: Nuclear and cell division in Bacillus subtilis: dormant nucleoids in stationary-phase cells and their activation.
abstract: The morphology of nucleoids and mesosomes of Bacillus subtilis in stationary-and lag-phase cultures was studied by making three-dimensional cell reconstructions in plastic of electron micrographs of serial sections. In cells from stationary cultures, the dormant nucleoids are frequently, but not always, spherical and the mesosomes are small and compact. It is suggested that the spherical nucleoids represent the resting stage in which replication and segregation have been completed. In cells from lag-phase cultures, the compact mesosomes develop into an elaborate system of tubes and wider sacs which become wrapped around the elongating nucleoids and invade the nucleoplasm in preparation for division.
mesh_terms: D001412:Bacillus subtilis / Q000254:growth & development / Q000648:ultrastructure*; D002455:Cell Division; D002467:Cell Nucleus / Q000648:ultrastructure; D006652:Histological Techniques; D008854:Microscopy, Electron; D008961:Models, Structural; D009940:Organoids / Q000648:ultrastructure