title: Preliminary observations on the effects on the organs of mice of administering some carbamate pesticides.
abstract: Two pesticides, Karbatox 75 and Unden, were used for the investigation, in daily doses of 20 mg per kg body weight, injected intraperitoneally during a period of 20 days. A comparatively low toxicity of these compounds for mice was ascertained. Among morphological changes were found: hypertrophy of the intestinal epithelium, a decrease in size of liver cells and a significant increase in number of Gomori-positive glia cells, as well as an increase in the volume of cell nuclei in the neurosecretory neurocytes of hypothalamus.
mesh_terms: D000818:Animals; D012721:Carbaryl / Q000633:toxicity; D002467:Cell Nucleus / Q000187:drug effects; D002875:Chromosomes / Q000187:drug effects; D007031:Hypothalamus / Q000648:ultrastructure; D007306:Insecticides / Q000633:toxicity*; D007620:Karyometry; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009457:Neuroglia / Q000648:ultrastructure; D001074:Propoxur / Q000633:toxicity; D013154:Spleen / Q000648:ultrastructure; D013737:Testis / Q000648:ultrastructure
chemical_list: D007306:Insecticides; D001074:Propoxur; D012721:Carbaryl