title: [T.R.H. test in 93 cases of thyroid disease].
abstract: The authors used the stimulation of TSH test by intravenous injection of TRH in 93 patients. They obtained a negative or weak response in thyrotoxicosis, toxic adenomas, and Means syndrome, and a normal response with non-extinctive hot nodules. The response was positive and high in primary hypothyroidism. The results are sometimes paradoxal in hypothalamo-pituitary pathology even after hypophysectomy: a delayed and elevated response is in favour of a pituitary reserve of non-utilised TSH. In non-functional goitres and thyroiditis, the sometimes positive responses obtained are an indication for substitutive and depressive therapy.
mesh_terms: D000236:Adenoma / Q000503:physiopathology; D006042:Goiter / Q000503:physiopathology; D006111:Graves Disease / Q000503:physiopathology; D006801:Humans; D006980:Hyperthyroidism / Q000503:physiopathology; D007037:Hypothyroidism / Q000503:physiopathology; D007275:Injections, Intravenous; D010901:Pituitary Function Tests; D010902:Pituitary Gland / Q000503:physiopathology*; D010903:Pituitary Gland, Anterior / Q000503:physiopathology*; D010911:Pituitary Neoplasms / Q000503:physiopathology; D012636:Secretory Rate / Q000187:drug effects; D013268:Stimulation, Chemical; D013959:Thyroid Diseases / Q000503:physiopathology*; D013960:Thyroid Function Tests; D013964:Thyroid Neoplasms / Q000503:physiopathology; D013972:Thyrotropin / Q000378:metabolism*; D013973:Thyrotropin-Releasing Hormone
chemical_list: D013973:Thyrotropin-Releasing Hormone; D013972:Thyrotropin
vernacular_title: Test à la t.r.h. dans 93 affections thyroïdiennes