title: [The clinical application of allergen-specific and total IgE determination in pediatric allergology (author's transl)].
abstract: Allergen specific IgE determination (Radio-Allergen-Sorbens-Test) were carried out on 150 patients 2 to 14 years old. The agreement with classical skin tests (Prick and intracutaneous tests) was for pollen allergies 87%, for allergies against house-dust and house-dust mites 80% and for allergies against animal denders 69%. There was however no agreement for allergies against molds (only 11%). The total IgE was measured in 51 children by radial immunodiffusion, pathologically high levels were found in 45% of patients. Allergen-specific IgE determinations (RAST) seem to be especially useful for young allergic children.
mesh_terms: D000293:Adolescent; D000485:Allergens; D002648:Child; D002675:Child, Preschool; D004391:Dust; D004847:Epithelial Cells; D006801:Humans; D006967:Hypersensitivity / Q000097:blood*; D005779:Immunodiffusion; D007073:Immunoglobulin E / Q000032:analysis*; D011058:Pollen; D012882:Skin Tests
chemical_list: D000485:Allergens; D004391:Dust; D007073:Immunoglobulin E
vernacular_title: Klinische Anwendung der allergen-spezifischen und Gesamt-IgE-Bestimmung in pädiatrischer Allergologie