[Antagonistic effect of a fraction isolated from Corynebacterium granulosum toward cyclophosphamide immunosuppression in mice].
A fraction isolated from Corynebacterium granulosum was shown to be capable of increasing significantly the antibody level in response to immunization of the Mouse with sheep red blood cells. The animals stimulated with this fraction become very resistant to the effect of cyclophosphamide. In contrast, the action of the fraction in previously immuno-suppressed animals is nil or very low.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D003352:Corynebacterium / Q000276:immunology*; D003520:Cyclophosphamide / Q000494:pharmacology*; D006388:Hemagglutinins / Q000096:biosynthesis; D007165:Immunosuppression Therapy; D051379:Mice; D013997:Time Factors
D006388:Hemagglutinins; D003520:Cyclophosphamide
Effet antagoniste d'une fraction isolée de Corynebacterium granulosum envers le pouvoir immunosuppresseur de la cyclophosphamide chez la souris