title: Intragenic deletions and salivary band relationships in Drosophila.
abstract: In the absence of assumptions pertaining to the organization and function of chromomeric DNA, the cytogenetic analysis of intragenic deletions that start at Notch and spread to the right or left of the locus suggests that the recombinational gene is bilaterally associated with salivary band 3C7. Either there are two genes resolved as a single cistron, or one must seek an alternative interpretation that allows some modicum of independent in the relationship between gene and band. Although we momentarily lean toward the hypothesis that gene and salivary band are separate entities on a binemic chromosome, alternative views can be devised, and the data must remain open to reinterpretation.--The recessive visible allele fa-swb behaves as a point mutant at the left end of the map and seems to be a deletion in the interval 3C6 to 7; we suspect some part of the band is missing. We have used the aberration in fa-swb as a cytological marker, isolated intragenic recombinants, and subjected them to examination. The analysis indicates that the chromosomal interchanges occurred to the right of 3C7.
mesh_terms: D000483:Alleles; D000818:Animals; D002869:Chromosome Aberrations; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D004331:Drosophila melanogaster / Q000648:ultrastructure*; D005260:Female; D005796:Genes; D005808:Genes, Recessive; D006579:Heterozygote; D008297:Male; D009154:Mutation; D011995:Recombination, Genetic; D012469:Salivary Glands / Q000648:ultrastructure; D012730:Sex Chromosomes