Microbial transformation of daunomycinone by Streptomyces aureofaciens B-96.
Daunomycinone, aglycone of the anthracycline antibiotic daunomycin, was transformed by a washed mycelia of Streptomyces aureofaciens B-96 in a buffer solution containing sucrose; the obtained product, dihydrodaunomycinone (9-(1-hydroxyethyl)-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-4-methoxy-5,12-naphthacenequinone), was identified by measuring basic physicochemical characteristics (IR, UV and visible spectra, mass spectra and NMR, optical rotation and m.p.).
D001711:Biotransformation; D055598:Chemical Phenomena; D002621:Chemistry; D003630:Daunorubicin / Q000032:analysis / Q000378:metabolism*; D006868:Hydrolysis; D013304:Streptomyces aureofaciens / Q000378:metabolism*
D003630:Daunorubicin