[Trypanocidal activity of some ellipticine derivatives against Trypanosoma cruzi cultured in vitro].
Some ellipticine derivatives showing antitumoral behaviour exhibit a trypanocide activity against in vitro cultures of T. cruzi. 9-Methoxy-6-methyl-ellipticine is the most active compound of this series: its lethal effect is comparable with that of ethidium bromide.
D000470:Alkaloids / Q000494:pharmacology*; D000818:Animals; D004611:Ellipticines / Q000494:pharmacology*; D014349:Trypanosoma cruzi / Q000187:drug effects* / Q000254:growth & development
D000470:Alkaloids; D004611:Ellipticines
Activité trypanocide de quelques dérivés de l'ellipticine sur Trypanosoma cruzi cultivé in vitro