[The effect of harmaline on sodium transport across isolated Rana esculents skin and Astacus leptodactylus branchiae].
Harmaline stimulates transport of sodium through the isolated frog skin when the alkaloid is added at low concentration (10(-5) to 10(-6) M) to the external medium. In the same conditions, it inhibits in vivo transport of sodium through the gills of the crayfish. It is proposed that these effects do not involve a (Na + K) ATPase but are the result of an interaction between harmaline and the sites of penetration of sodium on the external surface.
D000470:Alkaloids / Q000494:pharmacology*; D000818:Animals; D001001:Anura; D003400:Astacoidea; D001693:Biological Transport, Active / Q000187:drug effects; D005880:Gills / Q000378:metabolism*; D006246:Harmaline / Q000494:pharmacology*; D008566:Membranes / Q000187:drug effects; D011893:Rana esculenta; D012867:Skin / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*
D000470:Alkaloids; D012964:Sodium; D006246:Harmaline
Action de l'harmaline sur le transport de sodium à travers la peau isolèe de Rana esculenta et la branchie d'Astacus leptodactylus