title: A double-blind trial of intravenous thyrotrophin-releasing hormone in the treatment of reactive depression.
abstract: In a double-blind trial 600 mug. of thyrotrophin-releasing hormone (TRH) was compared with placebo given daily for four days to two groups of ten patients. There was no significant difference between the antidepressant effects of TRH and placebo.
mesh_terms: D000275:Adjustment Disorders / Q000188:drug therapy*; D000328:Adult; D002986:Clinical Trials as Topic; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D010919:Placebos; D011369:Professional-Patient Relations; D011569:Psychiatric Status Rating Scales; D012647:Self-Assessment; D013973:Thyrotropin-Releasing Hormone / Q000008:administration & dosage* / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D010919:Placebos; D013973:Thyrotropin-Releasing Hormone