[DNA intercalating agents: synthesis of structural analogs of ellipticine].
7 H, 10-methoxy pyrido [3,2-c], [4,3-c] and [3,4-c] carbazoles, and 7 H-pyrido [2,3-c] carbazole were synthesized by oxidative photocyclisation, to achieve a topological analysis of intercalation in DNA. From these parent compounds we have prepared the corresponding iodomethylates, 7-methyl and 10-hydroxy derivatives.
D000470:Alkaloids; D001665:Binding Sites; D002227:Carbazoles / Q000138:chemical synthesis*; D004247:DNA; D004611:Ellipticines; D011725:Pyridines / Q000138:chemical synthesis
D000470:Alkaloids; D002227:Carbazoles; D004611:Ellipticines; D011725:Pyridines; D004247:DNA
Composés d'intercalation de l'ADN. Synthése d'analogues structuraux de l'ellipticine