title: [RNA polymerase activity associated with a bunya virus (Lumbo)].
abstract: RNA dependent RNA polymerase has been demonstrated in purified Lumbo virus (Bunyavirus) which contains a single stranded segmented RNA. Divalent cations (Mn++ and Mg++) are required for optimal in vitro activity. Reaction products can be specifically annealed with the viral genome.
mesh_terms: D001103:Arboviruses / Q000201:enzymology*; D002042:Bunyamwera virus / Q000201:enzymology*; D002413:Cations, Divalent; D003609:Dactinomycin / Q000494:pharmacology; D007700:Kinetics; D009693:Nucleic Acid Hybridization; D012316:RNA Nucleotidyltransferases; D012367:RNA, Viral; D012324:RNA-Dependent RNA Polymerase / Q000378:metabolism; D012260:Ribonucleases / Q000494:pharmacology; D014529:Uridine
chemical_list: D002413:Cations, Divalent; D012367:RNA, Viral; D003609:Dactinomycin; D012316:RNA Nucleotidyltransferases; D012324:RNA-Dependent RNA Polymerase; D012260:Ribonucleases; D014529:Uridine
vernacular_title: Activité RNA polymérasique à un bunyavirus (Lumbo)