Drug-induced augmentation of coronary flow in vessels with maximum ischemic dilatation.
The possibility of drug-induced augmentation of coronary flow in vessels with maximum ischemic dilation has been investigated in anesthetized dogs. The auotperfused left anterior descending coronary artery was gradually narrowed to a "critical" degree at which hyperemic response to coronary occulsion was completely abolished...
D000241:Adenosine / Q000494:pharmacology; D000818:Animals; D003326:Coronary Circulation / Q000187:drug effects*; D003327:Coronary Disease / Q000150:complications / Q000503:physiopathology*; D003331:Coronary Vessels / Q000187:drug effects; D004108:Dilatation, Pathologic / Q000209:etiology / Q000503:physiopathology; D004176:Dipyridamole / Q000494:pharmacology; D004285:Dogs; D005260:Female; D008297:Male; D005996:Nitroglycerin / Q000494:pharmacology; D013997:Time Factors; D014655:Vascular Resistance / Q000187:drug effects; D014665:Vasodilator Agents / Q000494:pharmacology*
D014665:Vasodilator Agents; D004176:Dipyridamole; D005996:Nitroglycerin; D000241:Adenosine