Immunoassays of Acanthamoeba castellanii plasma membranes. Preliminary results.
To facilitate future diagnosis of Acanthamoeba infections in man, studies have been initiated to elicit antibodies to purified membranes from Acanthamoeba species. Specifically in this communication, preliminary results are reported on A. castellanii. Immunoprecipitation and immunofluorescent analyses suggest that the membrane antisera may allow specific identification at the species level and possibly strain identification.
D000562:Amebiasis / Q000175:diagnosis; D000818:Animals; D000918:Antibody Specificity; D002462:Cell Membrane / Q000276:immunology*; D002474:Cell-Free System; D056890:Eukaryota / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D007106:Immune Sera / Q000302:isolation & purification; D005779:Immunodiffusion; D007075:Immunoglobulin M; D007271:Injections, Intradermal; D007275:Injections, Intravenous; D011817:Rabbits; D012995:Solubility; D013045:Species Specificity
D007106:Immune Sera; D007075:Immunoglobulin M