title: The fate of newly formed satellite cells during compensatory muscle hypertrophy.
abstract: Compensatory hypertrophy was induced in the rat extensor digitorum longus muscle by extirpation of the synergistic tibialis anterior. Injections of 3H-thymidine (2 muCi/g body weight) was given at 24, 48, and 72 h after the operation. In animals killed immediately after the last injection both satellite cell nuclei and true muscle nuclei were labeled, whereas in animals killed 4 weeks later only true muscle nuclei were labeled. The results  are interpreted as indicating incorporation of newly formed satellite cells into the fibers during compensatory hypertrophy.
mesh_terms: D000818:Animals; D001345:Autoradiography; D006984:Hypertrophy; D008297:Male; D008854:Microscopy, Electron; D009119:Muscle Contraction; D009132:Muscles / Q000166:cytology*; D051381:Rats; D013936:Thymidine; D013997:Time Factors; D014316:Tritium
chemical_list: D014316:Tritium; D013936:Thymidine