Biochemical characterization of the human carbonic anhydrase variant CA Ih Hiroshima.
Some biochemical properties of a new red cell human carbonic anhydrase variant, CA Ih Hiroshima, have been determined. Evidence is presented that the amino acid substitution in the Japanese variant is not the same as the previously characterized CA Ic variant from Guam of similar electrophoretic mobility. Based on a comparison with the normal CA I isoenzyme, a proposal for the site of the amino acid substitution is presented.
D000595:Amino Acid Sequence; D002256:Carbonic Anhydrases / Q000032:analysis / Q000097:blood*; D004355:Drug Stability; D014644:Genetic Variation; D006358:Hot Temperature; D006801:Humans; D007564:Japan; D010455:Peptides / Q000032:analysis; D011487:Protein Conformation; D013053:Spectrophotometry
D010455:Peptides; D002256:Carbonic Anhydrases