Lymphocytes devoid of T and B cell markers in chronic lymphatic leukemia.
Peripheral lymphocytes of 16 patients with chronic lymphatic leukemia were studied for B and T cell markers with peroxidase-labelled anti-immunogloulin antisera and complement and spontaneous rosetting techniques. Increased numbers of B cells and normal numbers of T cells were noted. A significant observation was the presence of a large proportion of circulating lymphocytes without the conventional markers for T and B cells. This finding is correlated with clinical features.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D003165:Complement System Proteins; D006801:Humans; D007104:Immune Adherence Reaction; D007106:Immune Sera; D007070:Immunoglobulin A / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007945:Leukemia, Lymphoid / Q000276:immunology*; D007958:Leukocyte Count; D010544:Peroxidases; D011817:Rabbits / Q000276:immunology; D011947:Receptors, Antigen, B-Cell / Q000032:analysis; D013601:T-Lymphocytes / Q000276:immunology*; D013997:Time Factors
D007106:Immune Sera; D007070:Immunoglobulin A; D007075:Immunoglobulin M; D011947:Receptors, Antigen, B-Cell; D003165:Complement System Proteins; D010544:Peroxidases