[The diagnostic significance of immunoglobulin determination in chronic liver diseases. III. observations of progress (author's transl)].
55 patients with chronic aggressive hepatitis and 20 with liver cirrhosis were observed over a 2-year period. Liver biopsy was performed several times but no immunosuppressive therapy was carried out. In this way a comparison was made between biochemically and histomorphologically demonstrable alterations in the process with the immunoglobulins. Significant agreement between the clinical biochemical and histomorphological activities and the behavior of immunoglobulin can only be concluded from increased activity of the process. But in histological deterioration, no correlation to the immunoglobulins was established, with the exception of IGM.
D000328:Adult; D001706:Biopsy; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006505:Hepatitis / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008103:Liver Cirrhosis / Q000276:immunology*; D008297:Male; D008875:Middle Aged
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins
Die diagnostische Bedeutung der Immunglobulinbestimmung bei chronischen Lebererkrankungen. III. Verlaufsbeobachtungen