[NN-dimethylbiguanide attenuates the lipid disorders of rats on an atherogenic diet].
NN-dimethylbiguanide in rats fed a high cholesterol diet reduces lipidemia and liver cholesterol. In addition, this drug decreases the level of liver cholesterol in rats on a high cholesterol and high glyceride diet.
D000818:Animals; D001645:Biguanides / Q000494:pharmacology*; D002784:Cholesterol / Q000032:analysis / Q000097:blood; D002791:Cholesterol, Dietary / Q000009:adverse effects; D003864:Depression, Chemical; D004036:Diet, Atherogenic; D004041:Dietary Fats / Q000009:adverse effects; D005227:Fatty Acids / Q000097:blood; D006949:Hyperlipidemias / Q000209:etiology; D008099:Liver / Q000032:analysis / Q000187:drug effects; D008297:Male; D008687:Metformin / Q000494:pharmacology; D051381:Rats; D013268:Stimulation, Chemical
D001645:Biguanides; D002791:Cholesterol, Dietary; D004041:Dietary Fats; D005227:Fatty Acids; D008687:Metformin; D002784:Cholesterol
Atténuation par le NN-diméthylbiguanide des troubles lipidiques engendrés par des régimes athérogènes chez le rat