Disodium cromoglycate in immunological mast cell degranulation of mice: an experimental study.
Mast cell degranulation occurs at reproducible percentages when the specific antigen is injected into air bubbles of sensitized mice. A fourfold diminution of the degranulated mast cells was observed when 0.25 cc of a 1% solution of DSCG was injected into the bubble prior to the challenging injection. The difference is statistically significant.
D000818:Animals; D000941:Antigens; D004205:Cromolyn Sodium / Q000494:pharmacology*; D005260:Female; D007166:Immunosuppressive Agents; D008407:Mast Cells / Q000187:drug effects* / Q000276:immunology; D051379:Mice; D012710:Serum Albumin, Bovine / Q000276:immunology
D000941:Antigens; D007166:Immunosuppressive Agents; D012710:Serum Albumin, Bovine; D004205:Cromolyn Sodium