[Therapeutic possibilities in idiopathic headaches. Analysis of 1000 cases (author's transl)].
According to Pearson's method (correlation coefficient) the group of improved patients is 16.88% of the expected total result (frequency of attacks regressed to 50%, 25% or 0%): for cyproheptadine, pizotifene, methysergide, methergoline, histamine, clonidine, allylpropylmalonyl urea 'p' is less than 0.001, for cinnarizine less than 0.02. For hemicrania we used cinnarizine, cyproheptadine, clonidine, histamine, pizotifene and reserpine; for cluster headache, cinnarizine, cyproheptadine, clonidine, histamine and reserpine; for tension headache, cyproheptadine; for psychogenic headache, allylpropylmalonylurea. In attacks of hemicrania or paroxysmal crises with undulant headache or persistent headache, positive statistically significant results were obtained with a combination of indomethacin, prochlorperazine and caffeine.
D001241:Aspirin / Q000627:therapeutic use; D002110:Caffeine / Q000627:therapeutic use; D002936:Cinnarizine / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003000:Clonidine / Q000627:therapeutic use; D003533:Cyproheptadine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004878:Ergotamine / Q000627:therapeutic use; D006261:Headache / Q000188:drug therapy*; D006632:Histamine / Q000627:therapeutic use; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D008711:Metergoline / Q000627:therapeutic use; D008784:Methysergide / Q000627:therapeutic use; D008881:Migraine Disorders / Q000188:drug therapy; D010918:Pizotyline / Q000627:therapeutic use; D011346:Prochlorperazine / Q000627:therapeutic use; D012110:Reserpine / Q000627:therapeutic use; D012189:Retrospective Studies; D014508:Urea / Q000031:analogs & derivatives / Q000627:therapeutic use
D010918:Pizotyline; D008711:Metergoline; D003533:Cyproheptadine; D002936:Cinnarizine; D002110:Caffeine; D006632:Histamine; D012110:Reserpine; D014508:Urea; D003000:Clonidine; D004878:Ergotamine; D001241:Aspirin; D007213:Indomethacin; D008784:Methysergide; D011346:Prochlorperazine
Therapeutische Möglichkeiten bei idiopathischen Kopfschmerzen. Analyse von 1000 Fällen