Inner ear degeneration in acoustic neurinoma.
The temporal bones of three cases of acoustic neurinoma are described to illustrate histopathological features of inner ear lesions due to chronic partial obstruction of blood circulation by the tumor in the internal auditory meatus. Degenerative changes in the inner ear due to acoustic neurinoma were evaluated and compared with changes in the opposite ear. The main pathological findings in the inner ear which were attributed to the tumor were degeneration of nerve fibers and of ganglion cells, degeneration of the stria vascularis, degeneration of the tectorial membrane, fibrosis and ossification of a semicircular canal. Fairly good preservation of sensory cells was observed in the presence of total degeneration of nerve fibers and ganglion cells and subtotal degeneration of the stria vascularis.
D000368:Aged; D004428:Ear Neoplasms / Q000473:pathology* / Q000601:surgery; D007758:Ear, Inner / Q000473:pathology*; D005260:Female; D005724:Ganglia / Q000473:pathology; D006801:Humans; D008297:Male; D009442:Neurilemmoma / Q000473:pathology* / Q000601:surgery; D009999:Ossification, Heterotopic; D000159:Vestibulocochlear Nerve / Q000473:pathology