[Study of the cytogenetic activity of radioprotectors in a human lymphocyte culture. II].
Action of certain radioprotectors: 2-mercaptoethylamine HCl (MEA), cysteine HCl, 2-aminoethylsothiouronium (AET), dithiol 2,3-dimercaptopropansulphate Na (unithiol), aminopropylaminoethylthiophosphoric acid (gammaphos), cystaphos and 5-metoxytriptamine (mexamine) was studied as applied to human chromosome aberrations induced with thio-TEPA. It was shown that with an increase in thioTEPA and protectors concentrations their effect grows.
D008735:5-Methoxytryptamine / Q000494:pharmacology; D000255:Adenosine Triphosphate / Q000494:pharmacology; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D003539:Cystaphos / Q000494:pharmacology; D003545:Cysteine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects*; D008624:Mercaptoethylamines / Q000494:pharmacology; D008938:Mitosis; D009154:Mutation / Q000187:drug effects*; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D013852:Thiotepa / Q000494:pharmacology; D013997:Time Factors; D014494:Unithiol / Q000494:pharmacology; D000338:beta-Aminoethyl Isothiourea / Q000494:pharmacology
D008624:Mercaptoethylamines; D011837:Radiation-Protective Agents; D000338:beta-Aminoethyl Isothiourea; D008735:5-Methoxytryptamine; D014494:Unithiol; D000255:Adenosine Triphosphate; D013852:Thiotepa; D003545:Cysteine; D003539:Cystaphos
Izuchenie tsitogeneticheskoĭ aktivnosti radioprotektorov v kul'ture limfotsitov cheloveka. Soobshchenie II