Antigenic heterogeneity among monoclonal IgM: observations on guinea-pig sera.
Antisera against purified monoclonal IgM from patients with Waldenström's macroglobulinemia were raised in guinea-pigs. Absorption with normal human serum and heterologous macroglobulinemic serum resulted in an antiserum to a subgroup present in 5 of 54 sera.
D000818:Animals; D000888:Antibodies, Anti-Idiotypic; D006168:Guinea Pigs / Q000276:immunology*; D006801:Humans; D005779:Immunodiffusion; D007075:Immunoglobulin M / Q000032:analysis*; D008258:Waldenstrom Macroglobulinemia / Q000097:blood*
D000888:Antibodies, Anti-Idiotypic; D007075:Immunoglobulin M