title: Genome complexity and in vivo transcription in human leukemic leukocytes.
abstract: Human DNA contains 35 percent repetitive and 65 percent nonrepetitive sequences. Eight satellite DNAs have now been identified in human DNA. The highly repetitive non-satellite sequences are arranged in blocks 1,100 nucleotides long and interspersed with intermediate repetitive and nonrepetitive sequences greater than 2,500 nucleotides long. Approximately 2.5-3.9 percent of the nonrepetitive sequences are represented in total cellular RNA of normal and leukemic leukocytes.
mesh_terms: D001483:Base Sequence; D002499:Centrifugation, Density Gradient; D002843:Chromatin; D004247:DNA / Q000032:analysis*; D004273:DNA, Neoplasm / Q000032:analysis* / Q000097:blood; D004276:DNA, Satellite / Q000032:analysis* / Q000097:blood; D005838:Genotype; D006801:Humans; D007938:Leukemia / Q000235:genetics*; D007962:Leukocytes / Q000032:analysis*; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D009693:Nucleic Acid Hybridization; D012313:RNA / Q000032:analysis; D014158:Transcription, Genetic
chemical_list: D002843:Chromatin; D004273:DNA, Neoplasm; D004276:DNA, Satellite; D012313:RNA; D004247:DNA