Reduction of epileptic seizures through EEG biofeedback training.
Biofeedback training of the sensorimotor rhythm (SMR) was carried out in three male and three female adolescent epileptics and in two normal controls. The patients represented a cross-section of epilepsies including grand mal, myoclonic, afocal and psychomotor types. Three of the cases were mentally retarded. 12-14 Hz (SMR) activity was detected by a combination of sharp analog filtering and digital processing. The patients were provided with feedback whenever they produced 0.5 sec of 12-14 Hz activity of a specified amplitude. Additional feedback was provided for epileptiform activity slow waves or movement. Furthermore, feedback for SMR production was inhibited by digital logic circuitry when movement, slow waves or spikes were present. Seizure reduction was obtained in five of the six epileptics. Several patients showed increased percentage of SMR when feedback was provided and varying degrees of normalization in their EEG as demonstrated by fast Fourier, crossed power spectral density and coherence analyses.
D000293:Adolescent; D000328:Adult; D002648:Child; D003216:Conditioning, Operant; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology / Q000628:therapy*; D004832:Epilepsy, Absence / Q000628:therapy; D004833:Epilepsy, Temporal Lobe / Q000628:therapy; D004830:Epilepsy, Tonic-Clonic / Q000628:therapy; D005246:Feedback; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008607:Intellectual Disability / Q000503:physiopathology; D008297:Male; D010775:Photic Stimulation; D013003:Somatosensory Cortex / Q000503:physiopathology; D013036:Spasms, Infantile / Q000628:therapy