Pharmacological approaches to treating the obese patient.
It should be obvious from the foregoing discussion that, at the present time, there is not an acceptably safe and effective pharmacological treatment for obesity. This patent inadequacy of present drug regimens has spawned the investigation into the diverse pharmacological approaches reviewed in this paper as well as investigation into the intestinal bypass operation (see Chapter 10). We feel that the eventual, safe and effective therapy for obesity will come from the pharmacological realm. Glucose-blocking drugs, growth hormone analogues, and hydroxycitrate are but three of the potentially safe and effective approaches to the problem for the future. It will be truly fascinating to watch the development in the treatment of obesity and, specifically, the pharmacological treatment for this problem over the next five to ten years.
D000662:Amphetamines / Q000627:therapeutic use; D001067:Appetite Depressants / Q000009:adverse effects / Q000627:therapeutic use*; D001835:Body Weight; D002319:Cardiovascular System / Q000187:drug effects; D002490:Central Nervous System / Q000187:drug effects; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D002951:Citrates / Q000627:therapeutic use; D004140:Dinitrophenols / Q000627:therapeutic use; D005947:Glucose / Q000378:metabolism; D013006:Growth Hormone / Q000627:therapeutic use; D006801:Humans; D008053:Lipid Mobilization / Q000187:drug effects; D008747:Methylcellulose / Q000627:therapeutic use; D009765:Obesity / Q000188:drug therapy*; D009941:Organomercury Compounds / Q000627:therapeutic use; D010101:Oxygen Consumption / Q000187:drug effects; D010629:Phenformin / Q000627:therapeutic use; D010928:Placental Lactogen / Q000627:therapeutic use; D011374:Progesterone / Q000627:therapeutic use; D011941:Receptors, Adrenergic / Q000187:drug effects; D013963:Thyroid Hormones / Q000627:therapeutic use; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology; D014284:Triiodothyronine / Q000627:therapeutic use
D000662:Amphetamines; D001067:Appetite Depressants; D006063:Chorionic Gonadotropin; D002951:Citrates; D004140:Dinitrophenols; D009941:Organomercury Compounds; D011941:Receptors, Adrenergic; D013963:Thyroid Hormones; D014284:Triiodothyronine; D011374:Progesterone; D013973:Thyrotropin-Releasing Hormone; D013972:Thyrotropin; D013006:Growth Hormone; D008747:Methylcellulose; D010928:Placental Lactogen; D010629:Phenformin; D005947:Glucose