title: Influence of early training to cold environment on some neuroendocrine patterns in adult rats.
abstract: Experiments carried out on Wistar rats of either sex: controls; early trained to cold (day 1--30) and handled newborn rats, killed on day 105 show that cold exposure during neonatal period induces long-lasting changes, which persist during the adult life. The most important changes concern CNS metabolism (modifications of 32P-incorporation into cerebral phospholipids, phosphoproteins and nucleic acids) and thyroid function. The authors discuss the mechanisms of these changes and their biological significance.
mesh_terms: D000367:Age Factors; D000818:Animals; D001921:Brain / Q000378:metabolism; D003080:Cold Temperature; D004702:Endocrine Glands / Q000378:metabolism / Q000502:physiology*; D004781:Environmental Exposure; D009424:Nervous System Physiological Phenomena; D009696:Nucleic Acids / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D010750:Phosphoproteins / Q000378:metabolism; D010758:Phosphorus / Q000378:metabolism; D051381:Rats; D013997:Time Factors
chemical_list: D009696:Nucleic Acids; D010743:Phospholipids; D010750:Phosphoproteins; D010758:Phosphorus