Researches regarding the effect of total x-ray irradiation on the collagen metabolism in rats.
1. Hydroxyproline is an amino acid specific of collagen, so that any changes in its urinary concentration is a proof of the metabolical changes of collagen. 2. The basic value of hydroxyproline in rats investigated by us was of 270 +/- 49 mug/24 hours. 3. The total irradiation with 700 r induced a marked increase of urinary hydroxyproline, beginning after 24 hours and with a maximum level after 48 hours.
D000818:Animals; D003094:Collagen / Q000378:metabolism*; D003238:Connective Tissue / Q000528:radiation effects*; D006909:Hydroxyproline / Q000652:urine*; D011830:Radiation Effects; D051381:Rats
D003094:Collagen; D006909:Hydroxyproline