[Intracellular histamine content in human basophils and individual variation in allergic persons during densensitization].
A positive correlation has been found to exist between the percentage of basophiles and the histamine content in a suspension of washed human leukocytes obtained from allergic and healthy donors. The mean value of histamine per basophile was 1,9 +/- 0,3 pg. The leukocyte histamine content was measured as a function of time in a non-allergic person and during the desensitization period of allergic patients.
D001491:Basophils / Q000378:metabolism*; D002478:Cells, Cultured; D003888:Desensitization, Immunologic; D006632:Histamine / Q000378:metabolism*; D006801:Humans; D006967:Hypersensitivity / Q000378:metabolism*; D007700:Kinetics
D006632:Histamine
Taux d'histamine intra cellulaire dans les basophiles humains et variabilité individuelle chez des sujets allergiques au cours de la désensibilisation