[Metabolism of testosterone in rat Sertoli cells].
Aspermatogenic seminiferous tubules were incubated in presence of labelled testosterone. This steroid is converted into androstenedione and 5 alpha-dihydro-testosterone. This finding favours the hypothesis which gives the Sertoli cell an important role in germ cell maturation.
D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase / Q000378:metabolism; D000735:Androstenedione / Q000096:biosynthesis; D000818:Animals; D013196:Dihydrotestosterone / Q000096:biosynthesis; D008297:Male; D051381:Rats; D012708:Sertoli Cells / Q000201:enzymology / Q000378:metabolism* / Q000648:ultrastructure; D013739:Testosterone / Q000378:metabolism*
D013196:Dihydrotestosterone; D013739:Testosterone; D000735:Androstenedione; D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase
Métabolisme de la testostérone dans les cellules de Sertoli du rat