Effect of human serum plus streptokinase on spontaneous pulmonary metastases of Vx2 carcinomas transplanted in the maxillary sinus of the rabbit.
The effect of fibrinolysis induced by human serum plus streptokinase on the spontaneous pulmonary metastases of Vx2 carcinomas transplanted in the maxillary sinus of the rabbit was investigated. Human serum plus streptokinase could well induce fibrinolysis in the tumor-bearing rabbits. Induced fibrinolysis significantly promoted the spontaneous pulmonary metastases of Vx2 carcinomas.
D000818:Animals; D001769:Blood; D002277:Carcinoma; D005340:Fibrinogen / Q000378:metabolism; D005342:Fibrinolysis / Q000187:drug effects*; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D008441:Maxillary Neoplasms; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental; D011817:Rabbits; D012712:Serum Globulins / Q000032:analysis; D013300:Streptokinase / Q000494:pharmacology*
D012712:Serum Globulins; D005340:Fibrinogen; D013300:Streptokinase