title: [Weight reduction and sugar deprivation in glucose tolerance disturbance. A two-year study of 131 normal and overweight subjects (author's transl)].
abstract: 131 test subjects (male: female = 3.3 :1) of normal weight or in average of 20% overweight, and an average age of 55 years at the beginning of the study were followed for an average of 2 years (1-5 years) with regard to weight and glucose tolerance (50 g oral GTT). Group I (40 subjects) reduced weight and observed the ban on sugar, group II (69 subjects) were not able to lose weight but observed the deprivation of sugar and group III (22 subjects) increased weight and also did not observe the ban on sugar. All 109 subjects in groups I and II had a disordered glucose tolerance against only 8 in group III. During the period of observation there was a statistically confirmed improvement in glucose tolerance in 65% and normalization of the GT in 35% (no differences). In group III the deterioration in the glucose tolerance was statistically significant at the 1-hour value.
mesh_terms: D001835:Body Weight; D003920:Diabetes Mellitus / Q000517:prevention & control; D004032:Diet; D004040:Dietary Carbohydrates; D005260:Female; D005500:Follow-Up Studies; D005947:Glucose / Q000378:metabolism*; D005951:Glucose Tolerance Test; D006801:Humans; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy / Q000378:metabolism*; D011236:Prediabetic State / Q000178:diet therapy / Q000378:metabolism*
chemical_list: D004040:Dietary Carbohydrates; D005947:Glucose
vernacular_title: Gewichtsreduktion und Zuckerkarenz bei Glukosetoleranzstörung. 2-Jahres-Verlaufsstudie an 131 Personen mit Normal- und Ubergewicht