title: Induction of subcapsular cataracts in aniridic vervet monkeys by echothiophate.
abstract: Four surgically aniridic vervet monkeys with clear lenses received topical echothiophate iodide unilaterally daily for eight weeks. The opposite eyes received a control solution without echothiophate. All the echothiophate-treated eyes developed subcapsular lens opacities sttongly resembling those attributed to echothiophate in humans. The lenses in the control eyes remained clear.
mesh_terms: D000818:Animals; D002386:Cataract / Q000139:chemically induced*; D002522:Chlorocebus aethiops; D004456:Echothiophate Iodide / Q000009:adverse effects*; D005260:Female; D000882:Haplorhini; D007498:Iris / Q000502:physiology
chemical_list: D004456:Echothiophate Iodide