title: [M-component of serum formed by lambda-type Bence-Jones protein].
abstract: M-component in the serum composed of free light chains occurs rarely as evidenced by literature. In the investigations of the authors it was demonstrated that three M components obtained from patients with plasmocytoma were composed of free light chains type lambda. High concentration of low-molecular protein in serum was due, probably, to coexistent impairment of renal filtration. It is worth stressing that M component was a lambda-type chain which may explain the pathogenesis of renal failure caused by amyloidosis.
mesh_terms: D000686:Amyloidosis / Q000652:urine; D001536:Bence Jones Protein / Q000378:metabolism*; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000378:metabolism*; D007146:Immunoglobulin lambda-Chains / Q000378:metabolism* / Q000652:urine; D009194:Myeloma Proteins / Q000378:metabolism*; D010954:Plasmacytoma / Q000097:blood*
chemical_list: D007147:Immunoglobulin Light Chains; D007146:Immunoglobulin lambda-Chains; D009194:Myeloma Proteins; D001536:Bence Jones Protein
vernacular_title: M-komponent surowicy utworzony przez białko Bence-Jonesa typu lambda