title: Acute toxicity of substrates of the mixed function oxidase system in normal and phenobarbital-pretreated mice.
mesh_terms: D000632:Aminopyrine / Q000633:toxicity*; D000633:Aminopyrine N-Demethylase / Q000378:metabolism; D000814:Aniline Compounds / Q000633:toxicity*; D000815:Aniline Hydroxylase / Q000378:metabolism; D000818:Animals; D000983:Antipyrine / Q000633:toxicity*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D005037:Ethylmorphine-N-Demethylase / Q000378:metabolism; D014453:Glucuronosyltransferase / Q000378:metabolism; D007928:Lethal Dose 50; D008099:Liver / Q000201:enzymology*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D009022:Morphine Derivatives / Q000633:toxicity; D009251:NADPH-Ferrihemoprotein Reductase / Q000378:metabolism; D009596:Nitrophenols / Q000633:toxicity*; D010088:Oxidoreductases / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology*
chemical_list: D000814:Aniline Compounds; D009022:Morphine Derivatives; D009596:Nitrophenols; D000632:Aminopyrine; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D000815:Aniline Hydroxylase; D000633:Aminopyrine N-Demethylase; D005037:Ethylmorphine-N-Demethylase; D009251:NADPH-Ferrihemoprotein Reductase; D014453:Glucuronosyltransferase; D000983:Antipyrine; D010634:Phenobarbital