HL-A matching in thrombocyte and leukocyte transfusions.
A panel of 150 Rh+ and Rh-- donors was tested by the NIH-microcytotoxicity test against 90 antisera determing 21 HL-A antigens. For platelet and leukocyte transfusions, donors compatible in ABO and Rh groups as well as in HL-A antigens, were used. In some cases the donor and recipient were compatible in three HL-A antigens, in other cases the degree of compatibility was less satisfactory. Platelet and leukocyte concentrates were prepared by double thrombo- and leukocyte-pheresis. Before transfusions the cross cytotoxicity test with donor's lymphocytes was performed. No transfusion accidents occurred; in some patients a beneficial effect was noticed.
D000017:ABO Blood-Group System; D001782:Blood Donors; D001792:Blood Platelets / Q000276:immunology; D001803:Blood Transfusion; D003601:Cytotoxicity Tests, Immunologic; D006402:Hematologic Diseases / Q000628:therapy; D006649:Histocompatibility Antigens; D006650:Histocompatibility Testing; D006801:Humans; D007106:Immune Sera; D007962:Leukocytes / Q000276:immunology; D012204:Rh-Hr Blood-Group System; D013997:Time Factors
D000017:ABO Blood-Group System; D006649:Histocompatibility Antigens; D007106:Immune Sera; D012204:Rh-Hr Blood-Group System