[Pathogenesis of certain mycobacterioses in a chemically damaged liver of the rabbit (author's transl)].
Cirrhosis of the liver was provoked in adult rabbits by the administration of CCl4/0,3 ml subcutaneously two times a week during a period of six weeks. It was found that the infection by M. tuberculosis, M. avium and M. kansasii causes a considerably greater dissemination than in the case with the livers of rabbits unaffected by cirrhosis, and that even a non-pathogenic strain (M. intracellulare) is pathogenic, if the liver is affected. Our findings confirm the lowered resistance of a chemically damaged liver to the development of mycobacterial infection.
D000818:Animals; D008103:Liver Cirrhosis / Q000139:chemically induced / Q000150:complications*; D008737:Methyl Chloride; D009161:Mycobacterium / Q000472:pathogenicity*; D009164:Mycobacterium Infections / Q000150:complications*; D009162:Mycobacterium avium / Q000472:pathogenicity; D009169:Mycobacterium tuberculosis / Q000472:pathogenicity; D011817:Rabbits
D008737:Methyl Chloride
Uber die Pathogenese einiger Mykobakteriosen in chemisch geschädigter Kaninchenleber