[Proton NMR study of the autoassociation of ethidium bromide and of a dimer of phenanthridinium in aqueous solution].
The dilution shifts of the ethidium bromide 1 protons in aqueous solution lead to a determination of the self-association constant (K approximately 100 LM-1) and to the geometry of the complex. From these results, we propose a model for the folded form of the dimer: (4,7-diaza decamethylene) bis 5,5' (3,8-diamino-6 phenyl phenanthridinium) tetrachloride 2. All these results are discussed in relation with the biological properties of this dimer.
D004996:Ethidium; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010617:Phenanthridines; D011522:Protons; D012996:Solutions
D010617:Phenanthridines; D011522:Protons; D012996:Solutions; D004996:Ethidium
Etude par RMN 1H de l'autoassociation en solution aqueuse du bromure d'éthidium et dimère de phénanthridinium