Neonatal sepsis. A survey of eight year's experience at the Louisville General Hospital.
Information from 50 infants with neonatal septicemia from the Louisville General Hospital during an eight-year period (1964-1972) is presented. Twenty-five infants had gram-positive and the other 25 had gram-negative organisms. E. coli (13 cases), staphylococcus (10 cases), and hemolytic Streptococcus non-Group A (7 cases) were the mustcommon causative microorganisms. Only one of the 25 infants with gram-positive sepsis died; three with gram-negative sepsis died. Listeria monocytogenes was demonstrated in three infants; all had meningitis with no mortality. Early diagnosis, prompt intensive antibacterial therapy, and a high index of suspicion are most helpful for reducing the morbidity and mortality.
D001769:Blood / Q000382:microbiology; D001792:Blood Platelets; D001835:Body Weight; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology / Q000401:mortality; D007629:Kentucky; D007958:Leukocyte Count; D008089:Listeria monocytogenes / Q000302:isolation & purification; D008297:Male; D012189:Retrospective Studies; D018805:Sepsis / Q000209:etiology / Q000401:mortality; D012737:Sex Factors; D013291:Streptococcus / Q000302:isolation & purification; D013997:Time Factors