Anthropological studies among Libyans. Erythrocyte genetic factors, serum haptoglobin phenotypes and anthropometry.
Anthropological studies were done on 1276 Libyans from the Mediterranean cities of Tripoli and Benghazi, and from Sabha southward in The Sahara. The incidences of hemoglobin (Hb)-S and glucose-6-phosphate dehydrogenase (G-6-PD) deficiency were low in the coastal areas and significantly high in Sabha. Hb-C occurred sporadically in Tripoli and Sabha, and was absent from Benghazi in the east. One case of Hb-J Benghazi was noted. There were no sigificant differences in the ABO blood group and Rh0 (D) type distributions in the three localities. G-6-PD gene GdAfrequency was significantly high in Sabha. The lowest value of 6-phosphogluconate dehydrogenase (6-PGD) gene PGDA frequency and highest value of the gene PGDC were in Sabha. Adenylate kinase (AK) gene AK2 was only detectable in Tripoli. Acid phosphatase (AP) gene Pa frequency in Sabha was more than twice that in Tripoli and Benghazi, while pc was distinctly lower in Sabha than in the northern cities. Haptoglobin gene Hp1 frequency was almost identical in all areas. Anthropometric measurements revealed overall homogeneity of the three samples, closer similarity in the coastal region to adjacent North African populations, and Negroid influence in the Sahara Libyans. Anthropometry substantiated findings from blood markers.
D000017:ABO Blood-Group System; D000135:Acid Phosphatase / Q000032:analysis; D000263:Adenylate Kinase / Q000032:analysis; D000886:Anthropometry; D044383:Black People; D001827:Body Height; D001835:Body Weight; D002648:Child; D004534:Egypt; D005236:Favism / Q000453:epidemiology; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000453:epidemiology / Q000235:genetics; D006242:Haptoglobins / Q000032:analysis; D006447:Hemoglobin H / Q000032:analysis; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008002:Libya; D008297:Male; D010641:Phenotype; D010734:Phosphogluconate Dehydrogenase / Q000032:analysis; D044469:Racial Groups; D012204:Rh-Hr Blood-Group System; D013789:Thalassemia / Q000453:epidemiology / Q000235:genetics
D000017:ABO Blood-Group System; D006242:Haptoglobins; D006454:Hemoglobins; D012204:Rh-Hr Blood-Group System; D006447:Hemoglobin H; D010734:Phosphogluconate Dehydrogenase; D000263:Adenylate Kinase; D000135:Acid Phosphatase