[Use of an immunologic test for differential diagnosis of uterine chorionepithelioma and hydatid mole].
Polysaccharide complexes obtained by Westphal's method (modified by L. A. Zilbert et al) from the tissue of a primary tumour node and remote metastases (the lungs) of chorionoepithelioma of the uterus were used for differential diagnosis of chorionepithelioma of the uterus and hydatid mole. Investigations carried out showed that the reaction to the intradermal injection of polysaccharide complexes obtained from the remote metastases (the lungs) of chorionepithelioma of the uterus was highly specific and sensitive: positive reaction occurred only in the patients with chorionepithelioma of the uterus, and it was negative in the patients with hydatid mole. With a marked diminution (in the course of chemotherapy) of metastases in the lungs, when the immunological reaction to chorionic gonadotropin fell to 300--100 IU per litre of the urine, reaction to the intradermal injection of polysaccharide complexes from the metastases of chorionepithelioma of the uterus still remained positive.
D000951:Antigens, Neoplasm; D002822:Choriocarcinoma / Q000175:diagnosis* / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis* / Q000276:immunology; D005779:Immunodiffusion; D008175:Lung Neoplasms / Q000175:diagnosis*; D008207:Lymphatic Metastasis; D009362:Neoplasm Metastasis; D010920:Placenta / Q000032:analysis; D011134:Polysaccharides / Q000302:isolation & purification; D011247:Pregnancy; D012075:Remission, Spontaneous; D012882:Skin Tests; D014594:Uterine Neoplasms / Q000175:diagnosis*; D014599:Uterus / Q000032:analysis
D000951:Antigens, Neoplasm; D011134:Polysaccharides
Ispol'zovanie immunologicheskoĭ reaktsii dlia differentsial'noĭ diagnostiki khorionépiteliomy matki i puzyrnogo zanosa