title: A physiological approach to jaundice.
abstract: An understanding of the production, transport, hepatic uptake, biotransformation and excretion of bile pigments is necessary for the rational investigation of a patient presenting with jaundice. These aspects are reviewed, and at each step of bilirubin metabolism the clinical abnormalities giving rise to jaundice are indicated.
mesh_terms: D000328:Adult; D000367:Age Factors; D001646:Bile / Q000378:metabolism; D001663:Bilirubin / Q000097:blood / Q000378:metabolism*; D001692:Biological Transport; D002779:Cholestasis / Q000139:chemically induced / Q000378:metabolism; D005260:Female; D005333:Fetus; D014453:Glucuronosyltransferase / Q000378:metabolism; D006801:Humans; D007231:Infant, Newborn; D007565:Jaundice / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D011247:Pregnancy
chemical_list: D014453:Glucuronosyltransferase; D001663:Bilirubin