[Transplantation of vital islands of Langerhans in diabetic animal recipients].
Pancreatic islets of 300 g-Lewis-rats have been transplanted to 200 g streptozotocin-diabetic rats after preparation by manual-dissection method and by the Ficoll-method. The transplantation of more than 500 intact pancreatic islets into the peritoneal cavity of streptozotocin-diabetic-Lewis-rats results in a significant reduction of hyperglycemia, an increase of insulin output and a restoration of weight gain. It is suggested, that it is best to use the glucose-tolerance-test for interpretation of insulin-output and insulin-effect.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D002469:Cell Separation / Q000379:methods; D003920:Diabetes Mellitus / Q000097:blood / Q000628:therapy*; D016381:Islets of Langerhans Transplantation; D010529:Peritoneal Cavity; D051381:Rats; D014184:Transplantation, Homologous
D001786:Blood Glucose
Die Transplantation vitaler Langerhans'scher Inseln bei diabetischen Empfängertieren