Two IgM paraproteins differing in carbohydrate content in a patient with Waldenström's macroglobulinemia.
Two IgM paraproteins of different electrophoretic mobility were detected in the serum of a patient with Waldenstrom's disease. Both were type kappa, existed as high molecular weight polymers, and contained J-chain. The faster-moving protein contained a greater amount of carbohydrate, in both H and L chains.
D002241:Carbohydrates / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D004588:Electrophoresis, Cellulose Acetate; D006595:Hexosamines / Q000032:analysis; D006601:Hexoses / Q000032:analysis; D006801:Humans; D007122:Immunoelectrophoresis; D007143:Immunoglobulin Heavy Chains / Q000378:metabolism; D007144:Immunoglobulin J-Chains / Q000378:metabolism; D007075:Immunoglobulin M / Q000378:metabolism; D007145:Immunoglobulin kappa-Chains / Q000378:metabolism; D008970:Molecular Weight; D010266:Paraproteins / Q000378:metabolism; D012794:Sialic Acids / Q000032:analysis; D008258:Waldenstrom Macroglobulinemia / Q000276:immunology*
D002241:Carbohydrates; D006595:Hexosamines; D006601:Hexoses; D007143:Immunoglobulin Heavy Chains; D007144:Immunoglobulin J-Chains; D007075:Immunoglobulin M; D007145:Immunoglobulin kappa-Chains; D010266:Paraproteins; D012794:Sialic Acids