title: Increased disaccharidase activity in human diabetics.
abstract: Disaccharidase activity has been shown to be increased in human diabetics. Diabetics controlled on diet therapy showed no change in disaccharidase activity while two diabetics controlled on insulin or insulin-producing drug, glibenclamide, showed a fall in disaccharidase values toward normal. Possible causes for the increased disaccharidase activity in diabetes are discussed.
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D003920:Diabetes Mellitus / Q000178:diet therapy / Q000188:drug therapy / Q000201:enzymology*; D004186:Disaccharidases / Q000378:metabolism*; D005243:Feces / Q000032:analysis; D005260:Female; D005696:Galactosidases / Q000378:metabolism; D005959:Glucosidases / Q000378:metabolism; D005905:Glyburide / Q000627:therapeutic use; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D007583:Jejunum / Q000201:enzymology*; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D013393:Sucrase / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D007328:Insulin; D004186:Disaccharidases; D005696:Galactosidases; D005959:Glucosidases; D013393:Sucrase; D005905:Glyburide