Effect of eight weeks' physical training on muscle and connective tissue of the M. vastus lateralis in 69-year-old men and women.
Five one-hour exercise periods a week for 8 weeks included walking-jogging, swimming, gymnastics and ballgames for 26 healthy male and female 69-year-old pensioners. The mean maximal oxygen uptake of the men increased from 28.9 ml-kg-1-min-1 before training to 32.0 ml-kg-1-min-1 after training and for the women from 27.9 to 31.3 ml-kg-1-min-1. Muscle malate dehydrogenase activity was increased while that for lactate dehydrogenase decreased or remained the same. The activity of these enzymes was higher in the male both before and after training when compared with the female. However, the percentage number of slow twitch muscle fibers was nearly the same in both groups. Prolyl hydroxylase activity was increased after training especially in the female subjects. These results show that endurance-type training leads to an enhanced capacity for aerobic metabolism in older subjects and that collagen metabolism in skeletal muscles is affected by physical training.
D000368:Aged; D003238:Connective Tissue / Q000378:metabolism*; D005260:Female; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009124:Muscle Proteins / Q000378:metabolism; D009132:Muscles / Q000201:enzymology / Q000378:metabolism*; D010088:Oxidoreductases / Q000378:metabolism; D010101:Oxygen Consumption; D010806:Physical Education and Training; D010809:Physical Fitness; D013848:Thigh
D009124:Muscle Proteins; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D007770:L-Lactate Dehydrogenase