Hearing loss and cochlear pathology in monkeys after noise exposure.
Old World monkeys were exposed to octaveband noise from 0.5 to 8 kHz at 120 dB SPL, 8 hours daily for 20 days. Restricted permanent threshold shifts and localized loss of outer hair cells were produced, which were reasonably well correlated with the exposure frequencies. There was also a loss of both inner and outer hair cells at the extreme basal end of Corti's organ, regardless of the exposure frequency. Implications for human inner ear pathology are discussed.
D000161:Acoustic Stimulation; D000818:Animals; D001309:Auditory Threshold; D003051:Cochlea / Q000473:pathology*; D000882:Haplorhini; D006317:Hearing Loss, Noise-Induced / Q000209:etiology* / Q000473:pathology; D008251:Macaca; D008252:Macaca fascicularis; D008253:Macaca mulatta; D009622:Noise / Q000009:adverse effects*; D009925:Organ of Corti / Q000473:pathology; D010215:Papio