Congenital hypertrophic pyloric stenosis: A gastrin hypothesis pursued.
Pentagastrin and acetyl choline were shown to contract isolated strips of the circular pyloric muscle from baboons. These findings are compatible with the hypothesis that gastrin may have a part to play in the development or maintenance of congenital hypertrophiic pyloric stenosis of infancy.
D000109:Acetylcholine / Q000502:physiology; D000818:Animals; D005755:Gastrins / Q000494:pharmacology / Q000502:physiology*; D000882:Haplorhini; D006984:Hypertrophy / Q000151:congenital; D010215:Papio; D010418:Pentagastrin / Q000494:pharmacology / Q000502:physiology; D011707:Pyloric Stenosis / Q000151:congenital* / Q000209:etiology; D011708:Pylorus / Q000187:drug effects
D005755:Gastrins; D010418:Pentagastrin; D000109:Acetylcholine