Nonhuman primate restraint device for ocular drug studies.
A restraining device for nonhuman primates was designed which effectively prevented the animal from touching the eyes and thereby transferring a topically applied drug from 1 eye to the other. This permitted use of 1 eye of the same animal as a reliable control for observation of pharmacologic effects. The design permitted self-feeding by the animal. It did not produce chafing or pressure sores and resulted in no psychologic depression. The device has been used successfully for a 5-mo period.
D000818:Animals; D004435:Eating; D000882:Haplorhini; D007103:Immobilization; D007429:Intraocular Pressure / Q000187:drug effects; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D011323:Primates
D009883:Ophthalmic Solutions