title: [Administration of glucose 33 p.c. with added high doses of insulin within a scheme of early total parenteral alimentation to patients with shock-related excessive caloric demand (author's transl)].
abstract: 40 patients, who had been admitted to the ICU in a stage of shock were given glucose 33 p.c. with added high doses of insulin, administered within a scheme of early total parenteral alimentation, along with fat emulsions and aminoacid solutions. It is demonstrated that this type of nutrition is able to improve metabolisation of glucose in a phase of impaired glucose utilisation following shock. The duration of reduced glucose utilisation is 5-10 days during which period increased addition of insulin (24-18 U insulin/50 g glucose) is advisable. After this time the action of endogenous insulin was improved to such an extent that the added insulin could be reduced to 12 U insulin/50 g glucose up to the third week and later (up to 49 days) to 8 U insulin/50 g glucose.
mesh_terms: D000596:Amino Acids / Q000008:administration & dosage; D005223:Fats / Q000008:administration & dosage; D005947:Glucose / Q000008:administration & dosage* / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000008:administration & dosage*; D010288:Parenteral Nutrition; D010289:Parenteral Nutrition, Total; D012769:Shock / Q000628:therapy*
chemical_list: D000596:Amino Acids; D005223:Fats; D007328:Insulin; D005947:Glucose
vernacular_title: Verabreichung hochprozentiger Glucose mit grossen Insulindosen im Rahmen einer frühzeitigen totalen parentalen Ernährung bei Patienten mit schockbedingtem übersteigerten Kalorienbedarf