Some aspects of erythropoietic cell proliferation in erythroleukaemia.
Cytophotometric-autoradiographic investigations on erythropoiesis in erythroleukaemia indicate (1) the decreased labelling index of erythroblasts is explained by an increased percentage of these cells in G-i; (2) 'megaloblastoid' basophilic erythroblasts show a more pronounced decrease of their fraction in DNA synthesis than morphological normal cells; (3) 'megaloblastoid' early polychromatic normoblasts represent a non-proliferating cell population, and (4) the detected disturbance of cell proliferation - even though temporary - can be reversed.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001345:Autoradiography; D001491:Basophils / Q000378:metabolism / Q000648:ultrastructure; D001772:Blood Cell Count; D001853:Bone Marrow / Q000473:pathology; D002455:Cell Division; D002467:Cell Nucleus / Q000648:ultrastructure; D004247:DNA / Q000096:biosynthesis; D004920:Erythropoiesis; D005260:Female; D006801:Humans; D004915:Leukemia, Erythroblastic, Acute / Q000097:blood* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014617:Vacuoles
D004247:DNA