title: Gamma heavy chain disease; report of an autopsy case with a review of the literatures.
abstract: An autopsy report of a 76 years old Japanese male, who had suffered from gamma- HCD, was presented. This is the fifth case of gamma-HCD in Japan and this communication is the first autopsy report made on gamma-HCD in our country. The primary pathological alteration of this disorder is a neoplastic proliferation of atypical lympho-plasmacytes extending throughout the entire hematopoietic and parenchymatous organs. Pathological characteristics of our case were compared with the same disorders reported in the world literatures.
mesh_terms: D000368:Aged; D001344:Autopsy; D002455:Cell Division; D006362:Heavy Chain Disease / Q000473:pathology*; D006801:Humans; D007143:Immunoglobulin Heavy Chains; D007142:Immunoglobulin gamma-Chains; D008198:Lymph Nodes / Q000276:immunology / Q000473:pathology / Q000648:ultrastructure; D008297:Male
chemical_list: D007143:Immunoglobulin Heavy Chains; D007142:Immunoglobulin gamma-Chains