title: Distribution of prostaglandin E 9-KETOREDUCTASE AND TYPES I and II 15-hydroxyprostaglandin dehydrogenase in swine kidney medulla and cortex.
abstract: Prostaglandin E 9-ketoreductase, NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I), and NADP+-dependent 15-hydroxyprostaglandin dehydrogenase (type II) have been partially purified from swine renal medulla and cortex. Eleven times more NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity was found in the cortex than in the medulla. On the other hand, about twice as much NADP+-dependent dehydrogenase activity was found in the medulla than in the cortex. The prostaglandin 9-ketoreductase activities were equally distributed in the swine kidney cortex and medulla.
mesh_terms: D000429:Alcohol Oxidoreductases / Q000276:immunology / Q000302:isolation & purification* / Q000378:metabolism; D000818:Animals; D000882:Haplorhini / Q000276:immunology; D007668:Kidney / Q000201:enzymology*; D007672:Kidney Cortex / Q000201:enzymology*; D007679:Kidney Medulla / Q000201:enzymology*; D009928:Organ Specificity; D011453:Prostaglandins; D011817:Rabbits / Q000276:immunology; D011863:Radioimmunoassay; D013552:Swine
chemical_list: D011453:Prostaglandins; D000429:Alcohol Oxidoreductases