title: Penicillin sensitivity of gonococci. An evaluation of monitoring as an index of epidemiological control.
abstract: The penicillin sensitivities of 1,167 gonococci isolated during a 30-month period from male patients, and 794 gonococci isolated from female patients were analysed retrospectively. More strains from males were relatively resistant than those from females, and a higher proportion of relatively resistant organisms was isolated from each sex when the infection had been acquired outside the area served by the clinic. During the course of the study a fall in the number of relatively resistant strains was seen amongst the locally acquired organisms, whilst no such drop occurred in the strains acquired elswhere; it is postulated that improved contact tracing may have been responsible. Regular monitoring of the penicillin sensitivity of gonococci has been shown to be a sensitive index of gonorrhoea control.
mesh_terms: D005069:Evaluation Studies as Topic; D005260:Female; D006069:Gonorrhea / Q000517:prevention & control; D006801:Humans; D008297:Male; D009344:Neisseria gonorrhoeae / Q000187:drug effects*; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology*; D012008:Recurrence; D012189:Retrospective Studies; D012737:Sex Factors
chemical_list: D010406:Penicillins