title: RPL11, an R factor of Pseudomonas aeruginosa determining carbenicillin and gentamicin resistance.
abstract: R factor RPL11 from Pseudomonas aeruginosa determines multiple drug resistance including resistance to gentamicin and carbenicillin. The host range and incompatibility properties of RPL11 are those of incompatibility group P-2. Strains harboring the factor are not altered with respect to the major immunotypes 1 through 7 of Parke-Davis, or with respect to pyocin type by using the 18 indicators of Jones and co-workers. Analytical ultracentrifugation of crude extracts of R factor-containing strains shows a band of satellite DNA with a buoyant density of 1.717 g/cm(3).
mesh_terms: D002228:Carbenicillin / Q000494:pharmacology*; D005111:Extrachromosomal Inheritance; D005839:Gentamicins / Q000494:pharmacology*; D010403:Penicillin Resistance; D011550:Pseudomonas aeruginosa / Q000187:drug effects*
chemical_list: D005839:Gentamicins; D002228:Carbenicillin