[Oral application of calcium and vitamin D2 in allergic bronchial asthma (author's transl)].
In 12 patients with allergic bronchial asthma and airway obstruction the effect of calcium in combination with vitamin D 2 (calciferol), given orally, was tested in a cross-over double blind study. Within 60 minutes after application, a statistically significant reduction of airway resistance (Rt) and intrathoracic gas volume (IGV), as well as an increase of forced exspiratory one second volume (FEV1) and forced inspiratory one second volume (FIV1) was observed, in comparison with placebo. It is concluded that calcium, given orally in combination with calciferol, causes a decrease of airway obstruction in patients with allergic bronchial asthma.
D000284:Administration, Oral; D000328:Adult; D000403:Airway Resistance / Q000187:drug effects; D001249:Asthma / Q000188:drug therapy*; D002118:Calcium / Q000494:pharmacology / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004338:Drug Combinations; D004341:Drug Evaluation; D004872:Ergocalciferols / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006967:Hypersensitivity; D008297:Male; D008875:Middle Aged; D010919:Placebos; D012119:Respiration / Q000187:drug effects
D004338:Drug Combinations; D004872:Ergocalciferols; D010919:Placebos; D002118:Calcium
Orale anwendung von Kalzium plus Vitamin D2 bei allergischem Asthma bronchiale