title: Mutant of Dictyostelium discoideum defective in cell contact regulation of enzyme expression.
abstract: Previous work has shown that aggregation and disaggregation of cells during development of D. discoldeum significantly affects the expression of certain developmentally regulated enzymes. We have examined this cell contact regulation in a previously isolated mutant, Fr-17, and found that during the course of its developmental sequence it becomes specifically defective in this function.
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives / Q000494:pharmacology; D002448:Cell Adhesion; D002449:Cell Aggregation; D002469:Cell Separation; D003609:Dactinomycin / Q000494:pharmacology; D004492:Edetic Acid / Q000494:pharmacology; D008954:Models, Biological; D009024:Morphogenesis; D009154:Mutation; D009235:Myxomycetes / Q000166:cytology / Q000201:enzymology* / Q000378:metabolism; D009713:Nucleotidyltransferases / Q000096:biosynthesis*; D012313:RNA / Q000096:biosynthesis; D013997:Time Factors; D014158:Transcription, Genetic
chemical_list: D003609:Dactinomycin; D012313:RNA; D004492:Edetic Acid; D009713:Nucleotidyltransferases; D000241:Adenosine