Iron absorption in normal subjects and patients with idiopathic haemochromatosis: relationship with serum ferritin concentration.
In 52 normal subjects there was an inverse relationship between serum ferritin concentration and iron absorption. In 21 measurements in 15 patients with idiopathic haemochromatosis there was a similar inverse relationship but absorption was higher in relation to iron stores at all levels. Haemochromatotic patients with normal serum ferritin levels had abnormally high values for desferrioxamine chelatable iron and there was no correlation between chelatable iron and iron absorption.
D000328:Adult; D003676:Deferoxamine; D005260:Female; D005293:Ferritins / Q000097:blood*; D006432:Hemochromatosis / Q000097:blood / Q000378:metabolism*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007408:Intestinal Absorption; D007501:Iron / Q000097:blood / Q000378:metabolism*; D007504:Iron Radioisotopes; D008297:Male; D012737:Sex Factors; D014168:Transferrin / Q000032:analysis; D014915:Whole-Body Counting
D006454:Hemoglobins; D007504:Iron Radioisotopes; D014168:Transferrin; D005293:Ferritins; D007501:Iron; D003676:Deferoxamine