title: [Treatment of bradycardiac arrhythmias with depot-orciprenaline (author's transl)].
abstract: 24 patients with bradycardiac arrhythmias of various origin were treated with a new depot preparation  of orciprenaline. The special galenical preparation guarantees effectiveness ofr 8-10 hours. In 21 patients (87%), therefore, one dragee morning and evening was sufficient to obtain a mean rise in frequency of 57%. The preparation had to be discontinued in 3 cases because of side effects such as increase in ventricular extrasystoles, anginal complaints and critical rise of blood pressure in hypertension. Because of its trouble-free administration in a depot form the preparation not only offers a practical advantage over the short-acting commercial preparations, but also shows a reliable efficacy. It can therefore be given under regular supervision in all forms of bradycardiac arrhythmias with stable ventricular frequency and satisfactory cardiac output.
mesh_terms: D000368:Aged; D001919:Bradycardia / Q000188:drug therapy*; D003692:Delayed-Action Preparations; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006352:Heart Ventricles / Q000187:drug effects; D006801:Humans; D008297:Male; D009921:Metaproterenol / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D008875:Middle Aged
chemical_list: D003692:Delayed-Action Preparations; D009921:Metaproterenol
vernacular_title: Behandlung bradykarder Rhythmusstörungen mit Depot-orciprenalin