Evaluation of five mediums for the stabilization of Brucella abortus strain 19 dessicated by lyophilization.
Lyophilized Brucella abortus Strain 19 vaccines were prepared using five recommended mediums. These five vaccines were compared with each other and with liquid vaccine relative to their suitability for (1) maintaning distinguishing cultural characteristics; (2) maintaining viability during lyophilization; (3) quality of restoration; (4) maintaining viability under various storage temperatures and (5) maintaining stable, antigenic and virulence qualities.
D002004:Brucella Vaccine / Q000592:standards*; D002003:Brucella abortus / Q000276:immunology*; D003470:Culture Media; D004355:Drug Stability; D004356:Drug Storage; D005069:Evaluation Studies as Topic; D005612:Freeze Drying; D013696:Temperature
D002004:Brucella Vaccine; D003470:Culture Media