Polyacrylamide-gel disc electrophoresis of unconcentrated urine samples with special reference to Bence Jones proteins.
The polyacrylamide-gel disc electrophoresis has been applied to the fractionation of 27 samples of unconcentrated urine obtained from the patients with monoclonal gammopathy. It was shown that 44% of the whole Bence Jones protein bands examined were detected in the area between 0.70 and 0.90 expressed in terms of relative migration based on transferrin. The method provided a satisfactory separation of native urine proteins with good reproducibility and few technical difficulties. It may become an efficient tool in clinical chemistry.
D001536:Bence Jones Protein / Q000652:urine*; D004589:Electrophoresis, Disc; D006801:Humans; D006942:Hypergammaglobulinemia / Q000652:urine; D007147:Immunoglobulin Light Chains / Q000652:urine
D007147:Immunoglobulin Light Chains; D001536:Bence Jones Protein