title: Diazepam treatment of socially isolated monkeys.
abstract: Four rhesus monkeys were reared for the first eight months of life in total social isolation. One animal died during this period; the three remaining subjects were treated with diazepam in an isolation chamber, in their home cages, and in a playroom testing situation. Diazepam significantly decreased the self-disturbance behaviors of two subjects, and there was even the appearance of some social behaviors, although they were limited and not of the same quality as in nonisolated subjects. The authors discuss the implications of the data for understanding the significance of the social isolation syndrome in monkeys as a model for human psychoses.
mesh_terms: D000374:Aggression / Q000187:drug effects; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D003975:Diazepam / Q000494:pharmacology*; D005106:Exploratory Behavior / Q000187:drug effects; D005260:Female; D000882:Haplorhini; D006801:Humans; D007206:Individuality; D008253:Macaca mulatta; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D012008:Recurrence; D012919:Social Behavior; D012931:Social Environment; D012934:Social Isolation; D013997:Time Factors
chemical_list: D003975:Diazepam