title: Action of helenin on microorganisms.
abstract: The action of helenin on 10 genera of bacteria and yeasts and on 8 genera of dermatophytes was studied. The minimal inhibitory concentration for gram-positive bacteria ranged from 10 to 400 mug/ml, for gram-negative bacteria from 100 to 800 mug/ml, for yeasts from 200 to 750 mug/ml, and for dermatophytes from 50 to 500 mug/ml. Strains naturally resistant to helenin are very rare.
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology; D000995:Antitubercular Agents / Q000494:pharmacology; D003883:Arthrodermataceae / Q000187:drug effects; D001419:Bacteria / Q000187:drug effects*; D005658:Fungi / Q000187:drug effects*; D007783:Lactones / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012717:Sesquiterpenes / Q000494:pharmacology*; D015003:Yeasts / Q000187:drug effects
chemical_list: D000935:Antifungal Agents; D000995:Antitubercular Agents; D007783:Lactones; D012717:Sesquiterpenes