title: Clinical features related with centrencephalic EEG abnormality.
abstract: The clinical and electroencephalographical observations were performed on the two series of subjects and some relations between the EEG paroxysms of centrencephalic nature and clinical features were obtained. (1) One series comprised 154 children with the age-range of six to 10 years complaining of some learning disability. The abnormal EEG paroxysms of  centrencephalic nature were found in 31% of them. Behavior deviation and vegetative symtoms were the main clinical symptoms, appearing in 83% and 40% of these children respectively. It was supposed that children with both behavior deviation and vegetative symptoms and also those with vegetative symptoms alone had a close relation with the centrencephalic EEG paroxysms, and that learning disability might result from these two main symptoms. (2) The other series was composed of 50 patients in whom the age varied from 11 to 24 years, mainly 15-16, and 6-14/sec positive spikes were found. The behavior problems of these patients had the qualities which brought more practical sociopathic behaviors, and this was an exact difference from the behavior problems in the former series of children. In addition, vegetative disturbances and affective disorders were observed, and they are considered to relate to the behavior problems. The vegetative disturbances might play a role as an activating factor and the affective disorders as an underlying factor in the developing process of the behavior problems. Finally, it is concluded that although the fundamental clinical varieties of behavioral, affective and vegetative dysregulations were observed in the patients who had the centrencephalic EEG paroxysms, these three varieties were dependent on one another during the development of the individual patients.
mesh_terms: D000293:Adolescent; D000328:Adult; D000342:Affective Symptoms / Q000150:complications; D002648:Child; D002653:Child Behavior Disorders / Q000150:complications; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000209:etiology; D004827:Epilepsy / Q000150:complications / Q000503:physiopathology*; D006261:Headache / Q000150:complications; D006801:Humans; D007360:Intelligence; D013406:Suicide, Attempted