title: Radiation treatment of retinoblastoma.
abstract: In a series of 45 children with retinoblastoma, from the period 1953-1973, comprising 27 bilateral cases, 32 eyes were treated by irradiation. The different techniques of radiation are reviewed. In the present series small tumours were irradiated by local application of Stallard discs or Rosengren balls, while advanced cases were treated by external radiation. The results are discussed, and it is emphasized that the major factor of importance for the success of the treatment is the size of the tumour. Small tumours are cured, large ones are not. Future efforts must be directed towards early diagnosis. The treatment should be centralized in order to secure sufficient experience for the ophthalmologist and radiotherapist, as evaluation of the post- radiation fundus findings may present difficulties.
mesh_terms: D002675:Child, Preschool; D003037:Cobalt Radioisotopes / Q000627:therapeutic use*; D005134:Eye Neoplasms / Q000532:radiotherapy*; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011830:Radiation Effects; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D012160:Retina / Q000473:pathology / Q000528:radiation effects; D012175:Retinoblastoma / Q000532:radiotherapy*
chemical_list: D003037:Cobalt Radioisotopes