title: [Effective therapy of chronic arterial circulatory disorders with Nico-Padutin forte (author's transl)].
abstract: Over a period of 6 weeks, 90 patients of both sexes (principally male) aged from 38 to 81 years were treated with Nico-Padutin forte (BAY b 7979; 40 units kallikrein + 300 mg inositol nicotinate) for chronic arterial disorders of the lower extremities. Positive therapeutic results were obtained in 82 cases (91.2%) with a dosage of 1 tablet 3 times daily. The effect of the treatment was assessed by the cardinal symptom of intermittent claudication. The walking test was used as the clinical parameter. The significant lowering of the raised blood lipid levels (both in the cholesterol and triglyceride ranges) by treatment with BAY b 7979 is to be considered relevant in the importance of hyperlipidemia as a risk factor in arterial vascular diseases. As long as the controindications (acute myocardial infarction, acute hemorrhages) were given attention, tolerance was outstanding.
mesh_terms: D000328:Adult; D000368:Aged; D001157:Arterial Occlusive Diseases / Q000188:drug therapy*; D002784:Cholesterol / Q000097:blood; D002908:Chronic Disease; D004338:Drug Combinations; D005260:Female; D005684:Gait; D006801:Humans; D007610:Kallikreins / Q000627:therapeutic use*; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D009539:Nicotinic Acids / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D009539:Nicotinic Acids; D002784:Cholesterol; D007610:Kallikreins
vernacular_title: Effektive Therapie chronisch-arterieller Durchblutungsstörungen mit Nico-Padutin forte