The distribution of B and T lymphocytes in the peripheral blood of patients with Hodgkin's disease.
The distribution of thymus-dependent (T cells) and bone marrow-derived lymphocytes (B cells) was studied in 74 patients with Hodgkin's disease and 33 normal controls. A T cell deficit was found in untreated patients as well as in long-term survivors in remission. Therapy slightly enhanced the T cell depletion in Hodgkin's disease patients. Concomitant with this finding was slight increase of B cells.
D001402:B-Lymphocytes; D006689:Hodgkin Disease / Q000276:immunology* / Q000628:therapy; D006801:Humans; D007104:Immune Adherence Reaction; D007958:Leukocyte Count; D012075:Remission, Spontaneous; D013601:T-Lymphocytes / Q000276:immunology