Immunoglobulins associated with passive transfer of resistance to Taenia taeniaeformis in the mouse.
Mice were found to be protected against Taenia taeniaforMis infection by passive transfer of serum collected from donors 28 days after infection. The protective activity resided exclusively in the first fraction of 7S immunoglobulins eluting from DEAE-cellulose at pH 5.8 with 0.05 M phosphate buffer. This fraction contained 7Sgamma1 and 7Sgamma2 immunoglobulins but no detectable gammaA, gammaM or skin sensitizing activity. Fractions containing 7Sgamma 2 alone were ineffective in passive transfer.
D000818:Animals; D002498:Centrifugation; D002848:Chromatography, DEAE-Cellulose; D007106:Immune Sera; D007112:Immunity, Maternally-Acquired; D007116:Immunization, Passive; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007070:Immunoglobulin A; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M; D007136:Immunoglobulins; D051379:Mice; D010323:Passive Cutaneous Anaphylaxis; D012882:Skin Tests; D013621:Taenia / Q000276:immunology; D013622:Taeniasis / Q000276:immunology*
D007106:Immune Sera; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins