title: Synthesis of some 2-aminonicotinic acid derivatives.
abstract: The nucleophilic exchange of chlorine atom in 2-chloro-3-cyanopyridine with morpholine, piperidine and pyrrolidine was carried out. Acids, amides, thioamides, esters and hydrazides were derived from the obtained compounds (Fig. 1). Some of these compounds showed only moderate tuberculostatic activity.
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D008722:Methods; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D009539:Nicotinic Acids / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D009539:Nicotinic Acids