title: [Treatment of mastitis during the dry period of cows using the preparation Orbenin-dry cow].
abstract: The paper describes the study of the extent to which the use of the Orbenin -- dry cow preparation (with cloxacillin as the active substance) was successful in the treatment of mastitis caused by Streptococcus agalactiae. Effectiveness was evaluated on the basis of the bacteriological examination of the udder-quarter samples of milk obtained from the tested cows immediately before getting dry and after the resumption of lactation. The preparation was applied in a single dose at the beginning of the dry period at the rate of 500 mg cloxacillin per 1 udder quarter. In the first herd 11 cows were treated with a positive finding (str. agalactiae, penicillin-resistant) in 26 quarters. In two control examinations the causative agent was always detected in one quarter (not in the same), i. e. in 3.8% of the initial number. In the second herd the causative agent (sensitive to penicillin) was found in 67 quarters before treatment (the total number of cows tested being 25); after treatment it was found in two cows in one quarter in each case (3.0% of the initial number). In an informative testing of effectiveness, the Orbenin L. A. preparation, designed for lactating cows, was applied repeatedly (3 times with 48-hour intervals) to six cows with subclinical streptococcal mastitis (Str. agalactiae, penicillin-resistant, detected in 11 quarters). After treatment the causative agent was found only in one quarter during the second examination. The therapeutic effect can be considered very good; the form of the drug and the method of its application allow for prompt and easy application.
mesh_terms: D000818:Animals; D002417:Cattle; D003023:Cloxacillin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D007774:Lactation; D008414:Mastitis, Bovine / Q000188:drug therapy*; D011247:Pregnancy; D013292:Streptococcus agalactiae / Q000187:drug effects
chemical_list: D003023:Cloxacillin
vernacular_title: Lécba zánĕtů mlécné zlázy v období zaprahnutí prípravkem Orbenin-dry cow