The protective effect of the epimastigote forms of the PF strain of Trypanosoma cruzi against a virulent homologous infection.
Epimastigotes are assumed to be non-infective forms of trypanosomes. However, epimastigotes of the PF strain of the Trypanosoma cruzi when injected in mice, in a single low dose, conferred on the animals a very good protection against challenge of a virulent homologous strain.
D000818:Animals; D014355:Chagas Disease / Q000276:immunology*; D007114:Immunization; D008297:Male; D051379:Mice; D014349:Trypanosoma cruzi / Q000472:pathogenicity; D014774:Virulence