[Several molecular biologic characteristics of herpes virus isolated from lymphoblastoid cell lines from pavian hamadrils with malignant lymphoma].
Cells of KMPG-1 and SPG-2 cultures obtained from the bone marrow and spleen of baboon hamadryads with hemoblastosis produce herpes-like virus (HLV) having the density of 1.21 and 1.27 g/cm3 in sucrose and cesium chloride density gradients. The density of nucleocapsids is 1.26 and 1.30 g/cm3 correspondingly. The HLV DNA sedimentation constant- 54 +/- 3S, and its density 1.717 g/cm3. The sera of patients with Burkitt's lymphoma and nasopharyngeal carcinoma can bind H3-thymidine labelled HLV that evidences a close antigenic relationship between HLV and NV virus.
D000818:Animals; D000914:Antibodies, Viral; D000956:Antigens, Viral; D002051:Burkitt Lymphoma / Q000276:immunology; D002277:Carcinoma / Q000276:immunology; D002460:Cell Line; D000882:Haplorhini; D006564:Herpesviridae / Q000032:analysis / Q000302:isolation & purification* / Q000648:ultrastructure; D006801:Humans; D008223:Lymphoma / Q000382:microbiology*; D008854:Microscopy, Electron; D009303:Nasopharyngeal Neoplasms / Q000276:immunology; D010215:Papio / Q000382:microbiology*; D012367:RNA, Viral / Q000302:isolation & purification
D000914:Antibodies, Viral; D000956:Antigens, Viral; D012367:RNA, Viral
Nekotorye molekuliarno-biologicheskie kharakteristiki virusa gerpesa, izolirovannogo iz limfoblastoidnykh kletochnykh liniĭ ot pavianov gamadrilov so zlokachestvennoĭ limfomoĭ