title: Hyperbaric system for oxygen toxicity studies in the toad urinary bladder.
abstract: A hyperbaric research system to study the effects on membrane function of oxygen at pressures as high as 20 ATA has been designed. The system includes a pressure chamber capable of holding eight isolated toad bladder short-circuit current apparatuses and unique experimental gassing, diluent addition, and sampling systems which are monitored by a control panel mounted on the side of the pressure chamber. These externally controlled gassing, diluent, and sampling systems permit experimental manipulations at any ambient pressure and are a significant addition to the methodology of hyperbaric research.
mesh_terms: D000818:Animals; D001692:Biological Transport; D002024:Bufo marinus; D005740:Gases; D006931:Hyperbaric Oxygenation / Q000295:instrumentation*; D066298:In Vitro Techniques; D010100:Oxygen / Q000633:toxicity*; D012964:Sodium / Q000378:metabolism; D001743:Urinary Bladder / Q000378:metabolism*
chemical_list: D005740:Gases; D012964:Sodium; D010100:Oxygen