Binding effects of concanavalin A on a coronavirus.
Concanavalin A, a phytagglutinin, binds to the envelope of hemagglutinating encephalomyelitis virus, a Coronavirus. Concanavalin A treated virus suspensions lose their hemagglutination properties and there is a transient interference with infectivity. Electron micrographs show the Concanavalin A as a granular deposit adhering to the viral envelope and there is aggregation of the virus. Concanavalin A does not bind to virions stripped of their envelopes.
D002478:Cells, Cultured; D003208:Concanavalin A / Q000494:pharmacology*; D003332:Coronaviridae / Q000187:drug effects* / Q000254:growth & development / Q000648:ultrastructure; D006387:Hemagglutination, Viral
D003208:Concanavalin A