title: [Conservative therapy of angina pectoris using nifedipine (Adalat)].
abstract: 35 patients with angina pectoris or previous myocardial infarction were treated for the period of 6 weeks with a new calcium-antagonist (4-2'-Nitrophenyl-2,6-Dimethyl 1,4-dihydro-pyridin-3,5-dicarbon acid dimethylester) Adalat. The attacks of angina pectoris decreased by 75 percent, the need for nitroglycerin decreased by 84 percent. Examination at rest and under exercise before and during the treatment with Adalat showed when registered by electrocardiogram and by the mean pulmonary-capillary pressure a better tolerance under exercise during treatment as well as a decrease of the PCPm in rest and under exercise after 6 week-therapy with Adalat. No improvement during the period of treatment was seen in 2 patients, who suffered from a severe diffuse type of coronary artery disease.
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy*; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000009:adverse effects / Q000627:therapeutic use*; D005996:Nitroglycerin / Q000627:therapeutic use; D011725:Pyridines / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D011725:Pyridines; D005996:Nitroglycerin; D009543:Nifedipine
vernacular_title: Zur konservativen Therapie der Angina pectoris mit Nifedipine (Adalat)