title: Fractionation of the sequence organization of human DNA by preparative HgCl2/Cs2SO4 density gradients.
abstract: Human DNA has been fractionated on preparative HgCl2/Cs2SO4 density gradients. Repetitious sequences are found in DNA components of all base compositions but the (G + C)-rich sequences are enriched for repetitive sequences in (A + T)-rich components are tandemly arranged; those in (G + C)-rich components tend to be interspersed with single copy sequences. It is concluded that the interspersed repetitious sequences have high (G + C) compositions.
mesh_terms: D001483:Base Sequence; D002478:Cells, Cultured; D002499:Centrifugation, Density Gradient; D002586:Cesium; D004247:DNA; D006801:Humans; D008628:Mercury; D008970:Molecular Weight; D011687:Purines / Q000032:analysis; D011743:Pyrimidines / Q000032:analysis
chemical_list: D011687:Purines; D011743:Pyrimidines; D002586:Cesium; D004247:DNA; D008628:Mercury