New antibiotic XK-62-2 (sagamicin). II Taxonomy of the producing organism, fermentative production and characterization of sagamicin.
Cultures of Micromonospora species, strains MK 65 and MK 62, were found to produce a new antibiotic XK-62-2 (Sagamicin). Antibacterial and paperchromatographic data on an eluate from IRC50 treatment of fermentation beers indicated that XK62-2 is a new antibiotic with broad spectrum, basic, and water-soluble properties, probably closely related to the gentamicin C group of antibiotics.
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D050260:Carbohydrate Metabolism; D003470:Culture Media; D004926:Escherichia coli / Q000187:drug effects; D005285:Fermentation; D005690:Galactose / Q000378:metabolism; D005839:Gentamicins; D008847:Micromonospora / Q000145:classification* / Q000378:metabolism; D009584:Nitrogen / Q000378:metabolism; D012995:Solubility; D014994:Xylose / Q000378:metabolism
D000900:Anti-Bacterial Agents; D003470:Culture Media; D005839:Gentamicins; D014994:Xylose; D009584:Nitrogen; D005690:Galactose