[Conversion of chimpanzee O-erythrocytes into B-erythrocytes by human alpha galactosyltransferase].
The red blood cell antigens of the ABO system are not present in all the anthropïd Primates. The Chimpanzee, particularly, shows only the two genes A and O. The alpha-galactosyl transferase, present in the human sera of group B, has been used to fix a molecule of galactose on O red cells of Chimpanzee giving them a B specificity. If the B gene was present in the Chimpanzee it could consequently be expressed on the erythrocytes. This gene, probably present in an ancestor common to the anthropoïd apes and to Man disappeared in the Chimpanzee, perhaps at the origin of species.
D000017:ABO Blood-Group System; D000818:Animals; D005693:Galactosemias; D005700:Galactosyltransferases / Q000097:blood*; D005796:Genes; D006386:Hemagglutination Tests; D006801:Humans; D066298:In Vitro Techniques; D002679:Pan troglodytes / Q000097:blood*; D010802:Phylogeny
D000017:ABO Blood-Group System; D005700:Galactosyltransferases
Conversion des hématies O de chimpanzé en B par l'alpha-galactosyl transférase humaine