The role of Intralipid in prolonged parenteral nutrition. I. As a caloric substitute for glucose.
Three stable patients were studied in order to assess the role of intravenous fat solutions (Intralipid) in long-term home parental nutrition. The standard source of nonprotein calories (NPC) in these patients was 60% glucose. Replacing 40% of NPC by Intralipid was effective in maintaining nitrogen balance and allowed total infusion time to be reduced from 12 hr to 8 hr. The serum triglyceride level was significantly elevated when glucose was used as the sole source of NPC, whereas serum cholesterol was significantly elevated when 40% of NPC were supplied by Intralipid.
D002404:Catheterization; D002784:Cholesterol / Q000097:blood; D004734:Energy Metabolism; D005231:Fatty Acids, Unsaturated / Q000097:blood; D005947:Glucose; D006801:Humans; D009584:Nitrogen / Q000378:metabolism; D010288:Parenteral Nutrition; D010289:Parenteral Nutrition, Total; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
D005231:Fatty Acids, Unsaturated; D014280:Triglycerides; D002784:Cholesterol; D005947:Glucose; D009584:Nitrogen