The transport of 25-hydroxycholecalciferol in a New World monkey.
Albumin is responsible for the transport of 25-hydroxycholecalciferol in the Capuchin monkey. This was confirmed by gel filtration, analytical polyacrylamide-disc-gel electrophoresis, polyacrylamide-gel isoelectric focusing and a competitive protein-binding assay. Association constants of the serum transport proteins of a New and an Old World monkey towards 25-hydroxycholecalciferol were calculated; the transport protein in the New World monkey has a lower affinity for the vitamin D metabolite than the transport protein in the Old World primate.
D000818:Animals; D001667:Binding, Competitive; D001692:Biological Transport; D002352:Carrier Proteins / Q000378:metabolism; D000882:Haplorhini / Q000378:metabolism*; D006887:Hydroxycholecalciferols / Q000097:blood / Q000378:metabolism*; D012709:Serum Albumin / Q000378:metabolism; D014807:Vitamin D / Q000378:metabolism
D002352:Carrier Proteins; D006887:Hydroxycholecalciferols; D012709:Serum Albumin; D014807:Vitamin D