title: Full-thickness eye wall biopsy. II. In primates.
abstract: We devised a technique to perform an intact full-thickness eye wall biopsy in primates. An eye basket is sutured to the eye wall for stabilization. Trephines demarcate and incise a 4 to 7 mm. circumferential area of sclera; diathermy deepens the incision until perforation is achieved. The biopsy specimen is removed and immediately fixed for histologic evaluation, and the eye wall defect is covered by a 7 mm. scleral homograft. Our results showed that histologically excellent biopsies can be obtained with minimal damage to the eye.
mesh_terms: D000818:Animals; D001706:Biopsy / Q000295:instrumentation / Q000379:methods*; D002825:Chorioretinitis / Q000473:pathology; D004564:Electrocoagulation; D005123:Eye / Q000033:anatomy & histology / Q000473:pathology*; D000882:Haplorhini; D006801:Humans; D013508:Ophthalmologic Surgical Procedures; D011817:Rabbits; D012590:Sclera / Q000473:pathology; D014184:Transplantation, Homologous; D014207:Trephining