[In vitro effect of oxytocin on intracellular transit and secretion of milk proteins].
Mammary tissue slices are pulse-labelled for 3 mn in 3H leucine, then incubated in a chase-medium. When oxytocin (10(-6) UI/ml) is added 20 mn after the beginning of the pulse and for 5 mn, intracellular transit of radioactive milk proteins is accelerated and discharge in the incubation medium is increased. Hence it appears that oxytocin can stimulate secretion of milk proteins at the cellular level.
D000818:Animals; D002364:Caseins / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000032:analysis; D005260:Female; D006056:Golgi Apparatus / Q000032:analysis; D066298:In Vitro Techniques; D008321:Mammary Glands, Animal / Q000187:drug effects* / Q000378:metabolism; D008894:Milk Proteins / Q000378:metabolism*; D010121:Oxytocin / Q000494:pharmacology*; D011817:Rabbits; D012636:Secretory Rate / Q000187:drug effects
D002364:Caseins; D008894:Milk Proteins; D010121:Oxytocin
Effet de l'ocytocine in vitro sur le transit intracellulaire et la sécrétion des protéines du lait