[Pancreatic polypeptide islets and glucagon islets : distinct topographic distribution in rat pancreas].
The immunocytochemical technique for the cellular localization of hormones allows a precise identification of islet cell types responsible for the production of insulin, glucagon, somatostatin and pancreatic polypeptide. A systematic study of Rat pancreas has revealed a hitherto undescribed morphological heterogeneity of islets. In fact, the cellular composition of islets differs according to their anatomical distribution. The "PP islets" are preferentially located in the inferior 2/3 of the head of the pancreas, whilst "glucagon islets" populate the remainder of the gland.
D000818:Animals; D005260:Female; D005455:Fluorescent Antibody Technique; D005934:Glucagon / Q000032:analysis*; D007328:Insulin / Q000032:analysis; D007515:Islets of Langerhans / Q000166:cytology*; D008297:Male; D010179:Pancreas / Q000033:anatomy & histology* / Q000098:blood supply / Q000196:embryology; D010455:Peptides / Q000032:analysis*; D051381:Rats; D013004:Somatostatin / Q000032:analysis
D007328:Insulin; D010455:Peptides; D013004:Somatostatin; D005934:Glucagon
Ilots à polypeptide pancréatique (PP) et îlots à glucagon : distribution topographique distincte dans le pancréas de Rat (1)