title: Cytological findings in transrectal aspriation biopsy on hormone- and radio-treated carcinoma of the prostate.
abstract: The study reports cytological findings in 63 cases of radio- and/or oestrogen-treated carcinoma of the prostate. The different effects of therapy on the tumor cells in the cytological smear are described and discussed. An evaluation of the results, depending on the type of therapy, showed, that radio-treated tumors, due to the rapid and strong sclerosis of connective tissue, were less suitable for aspiration biopsy than hormone-treated tumors. Further, we were able to show that the effect of therapy in well-differentiated tumors is better than in poorly differentiated tumors. Cytological examination of treated prostate carcinoma is a simple method, quickly carried out, repeatable several times, and of high diagnostic value. Aspiration biopsy is most of all indicated for follow-up of the less well-differentiated and the hormone-treated carcinomas.
mesh_terms: D001707:Biopsy, Needle; D002277:Carcinoma / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D002454:Cell Differentiation; D004054:Diethylstilbestrol / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008679:Metaplasia; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy
chemical_list: D004054:Diethylstilbestrol