[Increased non-specific resistance to induction of malaria by sporozoites of Plasmodium berghei yoëlii in mice pretreated with a bacterial phospholipid extract].
The injection of a bacterial phosphospholipid extract increases resistance of mice subsequently challenged with sporozoïtes of Plasmodium berghei yoëlii. The pretreatment consisted of one injection of a suspension containing various amounts of phospholipid extract. It was e-fective when it shortly preceded the sporozoïtes inoculation. This resulted in total protection of a great number of animals against various amounts of sporozoïtes. There was a correlation between the dose of EBP injected and the degree of protection against various sporozoïtes.
D000818:Animals; D001419:Bacteria; D008288:Malaria / Q000517:prevention & control*; D008297:Male; D051379:Mice; D010743:Phospholipids / Q000627:therapeutic use*; D010962:Plasmodium berghei
D010743:Phospholipids
Augementation de la résistance non spécifique au paludisme induit par les sporozoïtes de Plasmodium berghei yoëlii chez des souris préalablement traitées par un extrait bactérien phospholipidique