Effect of depletion of vitamin A, followed by supplementation with retinyl acetate or retinoic acid, on regeneration of rat liver.
After partial hepatectomy the net increase in tissue weight and in RNA, DNA and proteins in the regenerating liver was markedly less in vitamin A-deleted or retinoic acid-supplemented male rats, compared with the corresponding normal control or retinyl acetate-supplemented ones.
D000085:Acetates / Q000494:pharmacology*; D000818:Animals; D004247:DNA / Q000032:analysis; D004224:Diterpenes; D004952:Esters; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology; D000882:Haplorhini; D006498:Hepatectomy; D008099:Liver / Q000032:analysis; D008115:Liver Regeneration / Q000187:drug effects*; D008297:Male; D011506:Proteins / Q000032:analysis; D012313:RNA / Q000032:analysis; D000084562:Retinyl Esters; D013997:Time Factors; D014212:Tretinoin / Q000494:pharmacology*; D014801:Vitamin A / Q000031:analogs & derivatives* / Q000378:metabolism* / Q000494:pharmacology*
D000085:Acetates; D004224:Diterpenes; D004952:Esters; D005231:Fatty Acids, Unsaturated; D011506:Proteins; D000084562:Retinyl Esters; D014801:Vitamin A; C009166:retinol acetate; D014212:Tretinoin; D012313:RNA; D004247:DNA