Amyloid fibril protein related to immunoglobulin lambda-chains.
Amyloid fibrils, isolated from the spleen of a patient with primary amyloidosis, had an N-terminal sequence showing a high degree of homology with lambda Bence Jones proteins. Anti-serum prepared to the amyloid protein detected a soluble factor, antigenically identical to the isolated fibril preparation.
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000682:Amyloid / Q000032:analysis*; D000686:Amyloidosis / Q000276:immunology; D001536:Bence Jones Protein / Q000032:analysis; D006801:Humans; D007106:Immune Sera; D007128:Immunoglobulin Fragments / Q000032:analysis*; D007146:Immunoglobulin lambda-Chains / Q000032:analysis*; D013154:Spleen / Q000276:immunology
D000596:Amino Acids; D000682:Amyloid; D007106:Immune Sera; D007128:Immunoglobulin Fragments; D007146:Immunoglobulin lambda-Chains; D001536:Bence Jones Protein