title: [Disorders of sinus-node function: diagnostic and clinical features (author's transl)].
abstract: Diagnostic right atrial stimulation was performed before and after atropine (1 mg i. v.) in 28 patients with or without ECG evidence of sinoatrial disease. Sinus-node recovery time was measured after rapid pacing had been stopped. Sinoatrial conduction time was calculated by premature atrial stimulation technique. Results are given for a control group of ten subjects with normal sinus-node function and 18 patients with sinoatrial disease. Using reaction of the pacemaker to single or multiple ectopic beats, it was found that sinus-node recovery time is determined not only by impulse generation but also sinoatrial conduction properties. The results indicate that, in a given patient, sinoatrial disease may be due to impairment of automaticity or sinoatrial conduction or a combination of both. Both stimulation procedures are of diagnostic value in patients who may require a pacemaker implantation.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001146:Arrhythmia, Sinus / Q000175:diagnosis*; D001285:Atropine; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D012849:Sinoatrial Node / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D001285:Atropine
vernacular_title: Störungen der Sinusknotenfunktion. Diagnostik und klinische Bedeutung