title: [Medically treated severe arterial hypertension. Long term course].
abstract: Antihypertensive therapy was performed in 47 patients having severe or malignant hypertension. The duration of the survey was two years. A highly significant decrease in blood pressure was observed. The decrease was not dependent on the type of antihypertensive treatment. Renal function was reduced at the beginning of the treatment. The renal insufficiency partly or totally diminished in course of time. Coronary insufficiency was noted in 5 patients. Coronarography showed thrombotic atherosclerosis in only one patient. A significant increase in lipids, cholesterol and triglycerids was nearly constant. The meaning of such facts is discussed.
mesh_terms: D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003327:Coronary Disease / Q000209:etiology; D004232:Diuretics / Q000627:therapeutic use; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007024:Hypotension, Orthostatic / Q000209:etiology; D007677:Kidney Function Tests; D050356:Lipid Metabolism; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013997:Time Factors
chemical_list: D000959:Antihypertensive Agents; D004232:Diuretics
vernacular_title: Hypertensions artérielles sévères traitées médicalement. Evolution à long terme