title: Toxicity of aerosol propellants in the respiratory and circularoty systems. X. Proposed classification.
abstract: The 15 propellants are grouped into four classes on the basis of results of investigation reported in this series of publications. Class 1 low-pressure propellants of high toxicity; Class 2 low-pressure propellants of intermediate toxicity; Class 3 high-pressure propellants of intermediate toxicity; and Class 4 high-pressure propellants of low toxicity.
mesh_terms: D000313:Adrenal Medulla / Q000187:drug effects; D000335:Aerosol Propellants / Q000145:classification / Q000633:toxicity*; D000336:Aerosols / Q000633:toxicity*; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D001794:Blood Pressure / Q000187:drug effects; D001980:Bronchi / Q000187:drug effects; D002073:Butanes / Q000494:pharmacology; D003864:Depression, Chemical; D004195:Disease Models, Animal; D004285:Dogs; D004980:Ethane / Q000031:analogs & derivatives; D000882:Haplorhini; D006321:Heart / Q000187:drug effects*; D006843:Hydrocarbons, Chlorinated / Q000633:toxicity; D006845:Hydrocarbons, Fluorinated / Q000633:toxicity; D008170:Lung Compliance / Q000187:drug effects; D008697:Methane / Q000031:analogs & derivatives; D051379:Mice; D011312:Pressure; D011407:Propane / Q000633:toxicity; D051381:Rats; D011941:Receptors, Adrenergic; D012119:Respiration / Q000187:drug effects*; D013045:Species Specificity; D014753:Vinyl Compounds / Q000633:toxicity
chemical_list: D000335:Aerosol Propellants; D000336:Aerosols; D002073:Butanes; D006843:Hydrocarbons, Chlorinated; D006845:Hydrocarbons, Fluorinated; D011941:Receptors, Adrenergic; D014753:Vinyl Compounds; D004980:Ethane; D008697:Methane; D011407:Propane