title: [Creatine kinase and intramuscular application of drugs (author's transl)].
abstract: The diagnosis of infarcts has been improved by inclusion of serum enzyme determinations, among other things. The determination of creatine phosphokinase (CPK) plays a particular role in hospital routine. In the present paper, the effect of intramuscular application of drugs on the serum CPK values is investigated. It is shown that an intramuscular injection is followed by a rise of serum CPK to pathological levels, so that CPK determination loses its significance in differential diagnosis.
mesh_terms: D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood*; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D003975:Diazepam / Q000008:administration & dosage; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis*; D012737:Sex Factors; D012965:Sodium Chloride / Q000008:administration & dosage; D013997:Time Factors
chemical_list: D012965:Sodium Chloride; D003402:Creatine Kinase; D003975:Diazepam
vernacular_title: Kreatinkinase und intramuskuläre Medikament-Applikation