[Behavior of gastrin, renin, aldosterone and electrolytes after administration of deglycyrrhizinized liquorice and carbenoxolone in healthy subjects].
We found that renin and aldosterone values do not drop except when administering Carbenoxolone. The significant rise of sodium (11) in the serum and the drop of the serum-potassium values are probably responsible for the undesirable Carbenoxolone side effects; they occur following the administration of deglycyrrhizinized succus. The rise of post-prandial gastrin in the serum of the above as compared to the values obtained from untreated controls is common to both.
D000328:Adult; D000450:Aldosterone / Q000097:blood*; D002229:Carbenoxolone / Q000009:adverse effects / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D004435:Eating; D005215:Fasting; D005755:Gastrins / Q000097:blood*; D006034:Glycyrrhetinic Acid / Q000031:analogs & derivatives*; D006035:Glycyrrhiza; D006801:Humans; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D011188:Potassium / Q000097:blood*; D011897:Random Allocation; D012083:Renin / Q000097:blood*; D012964:Sodium / Q000097:blood*; D013997:Time Factors
D005755:Gastrins; D010936:Plant Extracts; D000450:Aldosterone; D012964:Sodium; D012083:Renin; D002229:Carbenoxolone; D006034:Glycyrrhetinic Acid; D011188:Potassium
Das Verhalten von Gastrin, Renin, Aldosteron und Elektrolyten nach deglycyrrhiziniertem Succus liquiritiae und Carbenoxolon bei Gesunden.