Gel precipitin tests for hepatitis-B surface antigen. False positive reactions due to the presence of staphylococcal antigen in contaminated plasma samples.
Plasma samples contaminated with coagulase-positive staphylococci were found to give a false positive precipitin line for hepatitis-B surface antigen in gel tests. The staphylococcal antibody was found to be present in both normal immunoglobulin and anti-hepatitis-B surface antigen immunoglobulin preparations and also in many normal plasma samples.
D000942:Antigens, Bacterial / Q000009:adverse effects*; D005189:False Positive Reactions; D006511:Hepatitis B Antigens / Q000032:analysis*; D006801:Humans; D005779:Immunodiffusion; D010949:Plasma / Q000032:analysis; D013210:Staphylococcus / Q000276:immunology
D000942:Antigens, Bacterial; D006511:Hepatitis B Antigens