[Immunization in the range of HL-A antigen system in volunteers immunized with small doses of blood incompatible in the Rh system].
Thirty-six healthy men Rh-negative were immunized with whole Rh-positive blood for production of anti-D antibodies were observed for development of anti-leucocyte antibodies determined by incidental incompatibility in HL-A antigens. Small doses of blood containing 25-35 X 10(6) white blood cells were found to be sufficient for production of weak anti-leucocyte antibodies in 91.7% of immunized subjects. The ability to produce anti-leucocyte antibodies was nearly twice as high as the ability to produce anti-Rh antibodies. No correlation was observed between the ability of immunization in the range of erythrocyte or leucocyte antigens.
D000917:Antibody Formation; D001787:Blood Group Incompatibility / Q000276:immunology*; D006648:Histocompatibility; D006649:Histocompatibility Antigens / Q000032:analysis*; D006801:Humans; D007114:Immunization; D007962:Leukocytes / Q000276:immunology; D008297:Male; D012204:Rh-Hr Blood-Group System
D006649:Histocompatibility Antigens; D012204:Rh-Hr Blood-Group System
Immunizacja w zakresie antygenów układu HL-A u ochotników uodpornianych małymi dawkami krwi niezgodnymi w zakresie układu Rh