Decidua: a possible source of amniotic fluid prolactin.
The source of amniotic fluid prolactin was investigated with the use of amnion, chorion, placenta, and decidual tissue taken from term human pregnancy. Decidua alone of these tissues contained significant quantities of prolactin. The release of decidual prolactin was affected by the presence or absence of oxygen and protein, and the amount of prolactin released far exceeded the decrease in tissue content during incubation. It is concluded that: (1) decidua may be a major source of amniotic fluid prolactin, (2) synthesis of prolactin occurs during incubation of decidua, and (3) sufficient prolactin is present in the decidua to account for that found in amniotic fluid at term.
D000650:Amnion / Q000378:metabolism; D000653:Amniotic Fluid / Q000378:metabolism*; D002823:Chorion / Q000378:metabolism; D003470:Culture Media; D046508:Culture Techniques; D003656:Decidua / Q000378:metabolism*; D005260:Female; D005865:Gestational Age; D006801:Humans; D010101:Oxygen Consumption; D010920:Placenta / Q000378:metabolism; D011247:Pregnancy; D011388:Prolactin / Q000096:biosynthesis*; D011506:Proteins / Q000378:metabolism
D003470:Culture Media; D011506:Proteins; D011388:Prolactin