title: [Ulceration of the skin in necrobiosis lipoidica (author's transl)].
abstract: As a supplement to earlier investigations, a case of a 46 year old female patient is reported who has suffered from necrobiosis lipoidica granulomatosa with ulceration for 17 years. A marked remission was obtained by treatment with anti-inflammatory and immunosuppressive therapy. It is pointed out that under the usual treatment when ulcers of the lower leg and other areas of the skin do not heal, after exclusion of malignancies, necrobiosis lipoidica diabeticorum or necrobiosis lipoidica granulomatosa must be considered, especially as prophylactic examinations may arise.
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D005528:Foot; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007871:Leg Ulcer / Q000175:diagnosis; D008875:Middle Aged; D009335:Necrobiosis Lipoidica / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D009539:Nicotinic Acids / Q000627:therapeutic use; D012877:Skin Manifestations; D012883:Skin Ulcer / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D014647:Varicose Ulcer / Q000175:diagnosis
chemical_list: D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D009539:Nicotinic Acids
vernacular_title: Hautulzerationen bei Necrobiosis lipoidica