title: Photoreceptor mutant of Drosophia: is protein involved in intermediate steps of phototransduction?
abstract: In norpA mutants of Drosophila melanogaster the phototransduction process is either partially or completely blocked. By using a temperature-sensitive allele, we have found that that norpA mutation has little or no effect on either the rhodopsin-metarhodopsin transition or the machinery of quantum bump production. Thus, the norpA lesion appears to be localized in the intermediate process of phototransduction. Because a temperature-sensitive allele of norpA has been isolated, the norpA gene probably encodes a protein involved in the process.
mesh_terms: D000818:Animals; D001692:Biological Transport; D004331:Drosophila melanogaster; D007700:Kinetics; D008564:Membrane Potentials; D008565:Membrane Proteins / Q000502:physiology*; D009154:Mutation; D010786:Photoreceptor Cells / Q000502:physiology; D012243:Rhodopsin / Q000502:physiology; D012964:Sodium / Q000378:metabolism; D013696:Temperature
chemical_list: D008565:Membrane Proteins; D012243:Rhodopsin; D012964:Sodium