Clinical use of meptazinol.
Meptazinol, a new analgesic, was used at two different times of surgery: a) by the I.V. route peroperatively (1.6 mg/kg bodyweight with a maximum of 125 mg), b) by the I.M. route postoperatively (100 mg). When used I.V. peroperatively it does not seem to be a real progress, due to its poor neurovegetative protection and side-effects. However used I.M. postoperatively it seems a good analgesic drug with rapid onset and with few side effects.
D000328:Adult; D000368:Aged; D000700:Analgesics / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D000768:Anesthesia, General / Q000379:methods*; D001381:Azepines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D002245:Carbon Dioxide / Q000097:blood; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D008140:Lorazepam / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010149:Postoperative Pain / Q000188:drug therapy*
D000700:Analgesics; D001381:Azepines; D002245:Carbon Dioxide; D008140:Lorazepam; D010100:Oxygen