[Properties of anti-LH-RH serums induced by 2 different immunogens].
Several anti-LH RH antisera have been raised in Rabbits given as immunogen the synthetic decapeptide linked to bovine serum albumin by carbodiimide or bis-diazotized benzidine. Antibodies obtained with CDI as a coupling agent showed the highest titers and affinities enabling measurement of LH RH levels lower than 1 pg/tube. The specificity of the antisera, particularly toward 13 fragments of the molecule, were similar irrespective of the immunogen used.
D000818:Animals; D000917:Antibody Formation; D003429:Cross Reactions; D007987:Gonadotropin-Releasing Hormone / Q000276:immunology*; D006241:Haptens; D007106:Immune Sera; D010446:Peptide Fragments; D011817:Rabbits; D011863:Radioimmunoassay
D006241:Haptens; D007106:Immune Sera; D010446:Peptide Fragments; D007987:Gonadotropin-Releasing Hormone
Propriétés d'antisérums anti-LH RH induits par deux immunogènes différents