title: Melanocytic activity in leprosy lesions with special reference to cellular infiltrate.
abstract: To assess the correlation, if any, between the clinical hypopigmentation in leprosy affected skin and the inflammatory cellular infiltrate in d rmis, skin tissue sections from the maculo-anaesthetic and tuberculoid lesion of 50 cases were studied with Dopa and H & E stains. The results are indicative of (i) proportionate lack of Dopa oxidase activity in the hypopigmented leprosy lesions in commensuration with the relative degree of clinical hypopigmentation; (ii) cellular infiltrate is not related with the clinical hypopigmentation or dopa oxidase activity.
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D007918:Leprosy / Q000150:complications / Q000201:enzymology / Q000473:pathology*; D008297:Male; D008544:Melanocytes / Q000473:pathology*; D014442:Monophenol Monooxygenase / Q000378:metabolism; D010859:Pigmentation Disorders / Q000209:etiology*; D012867:Skin / Q000201:enzymology
chemical_list: D014442:Monophenol Monooxygenase