title: A feedback control of cell cycle parameters in Tetrahymena.
abstract: Protein and RNA contents of individual cells were measured cytophotometrically and related to the duration of individual generation times. Constant amounts of RNA per cell at division, and generation time-dependent protein contents, resulted in generation time-specific RNA/protein ratios. Experimental reduction of these ratios by inhibition of RNA synthesis stimulated premature macronuclear S phases.
mesh_terms: D000818:Animals; D002455:Cell Division / Q000187:drug effects; D003609:Dactinomycin / Q000494:pharmacology; D011506:Proteins / Q000378:metabolism; D012313:RNA / Q000096:biosynthesis / Q000378:metabolism; D013769:Tetrahymena pyriformis / Q000254:growth & development*
chemical_list: D011506:Proteins; D003609:Dactinomycin; D012313:RNA