Plasma-membrane-associated immunoglobulins and other polypeptides of pig mesenteric node lymphocytes.
Plasma membranes from pig mesenteric lymph-node lymphocytes contain a large number of polypeptide chains ranging in molecular weight from 20,000 to greater than 470,000, with a major component of 46,000. There are approx. 12-15 glycoproteins. The membranes contain immunoglobulin G, which comprises 0.6% of the total protein. Immunoglobulin M is also detected, but has not been accurately quantified for technical reasons. Possible origins of the membrane-associated immunoglobulin are briefly discussed. It is concluded that the immunoglobulin is probably associated with the plasma membrane in the intact cell.
D000818:Animals; D002462:Cell Membrane / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D006023:Glycoproteins / Q000032:analysis; D007106:Immune Sera; D005779:Immunodiffusion; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008198:Lymph Nodes / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D008854:Microscopy, Electron; D008970:Molecular Weight; D010455:Peptides / Q000032:analysis; D011947:Receptors, Antigen, B-Cell / Q000032:analysis*; D012756:Sheep / Q000276:immunology; D013552:Swine
D006023:Glycoproteins; D007106:Immune Sera; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D010455:Peptides; D011947:Receptors, Antigen, B-Cell