title: Immunofluorescent and migration inhibition studies in rats with experimental myocardial infarction.
abstract: The appearance of circulating anti-heart antibodies and myocardium-bound antibodies was demonstrated after experimental myocardial infarction induced by coronary ligation or high doses of isoproterenol in rats. Rat heart homogenate and mitochondria at 500 microgram/ml protein level inhibited the migration of leucocytes obtained from rats following myocardial infarction. The immunological consequences were similar in infarctions induced by coronary ligation or isoproterenol treatment.
mesh_terms: D000818:Animals; D000906:Antibodies; D000918:Antibody Specificity; D002464:Cell Migration Inhibition; D005455:Fluorescent Antibody Technique; D007545:Isoproterenol; D007962:Leukocytes / Q000276:immunology; D009203:Myocardial Infarction / Q000209:etiology / Q000276:immunology*; D009206:Myocardium / Q000276:immunology; D009928:Organ Specificity; D051381:Rats; D013997:Time Factors
chemical_list: D000906:Antibodies; D007545:Isoproterenol