Retroperitoneal transposition of the spleen and portal hypertension.
Three experiments are described in which it is shown that when the spleen is transposed to the retroperitoneal tissues, collaterals from between it and the systemic venous circulation. The first experiment was done on normal rats, the second in rats rendered cirrhotic and the third in a dog and a baboon. It is suggested that retroperitoneal transposition of the spleen may be a useful therapeutic measure in portal hypertension in humans.
D000818:Animals; D003097:Collateral Circulation; D004285:Dogs; D000882:Haplorhini; D006975:Hypertension, Portal / Q000628:therapy*; D008106:Liver Cirrhosis, Experimental / Q000628:therapy; D008297:Male; D009852:Omentum / Q000601:surgery; D010215:Papio; D051381:Rats; D012187:Retroperitoneal Space / Q000098:blood supply; D013154:Spleen / Q000098:blood supply / Q000637:transplantation*; D014182:Transplantation, Autologous; D014680:Veins