[Chances of reducing the formation of immune antibodies after massive transfusions in open heart surgery (author's transl)].
Children, young people and women at the age of possible maternity form the majority of patients operated by extracorporal circulation. A longterm planning of these operations should also have donor in call, who are compatible with the patients' Rh groups and Kell antigens. Having practiced such a selection of donors we succeeded in reducing the formation of immune antibodies. 6 out of 330 patients had antibodies, but 4 had been sensibilized before operation. In the case of the other 2 it would not be excluded that they might have been immunized a long time ago. We emphasize the importance of hemodilution, strict indication of every postoperative therapy with red cells and the autologous transfusion.
D000017:ABO Blood-Group System; D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D001782:Blood Donors; D001787:Blood Group Incompatibility / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D001803:Blood Transfusion; D002648:Child; D005112:Extracorporeal Circulation; D005260:Female; D006801:Humans; D007518:Isoantibodies; D007519:Isoantigens; D007626:Kell Blood-Group System; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D012204:Rh-Hr Blood-Group System; D065227:Transfusion Reaction
D000017:ABO Blood-Group System; D007518:Isoantibodies; D007519:Isoantigens; D007626:Kell Blood-Group System; D012204:Rh-Hr Blood-Group System
Möglichkeiten zur Reduzierung der Immunantiköperbildung nach Massivtransfusionen in der Thoraxchirurgie