title: Development, production and quality control of clinically applied antilymphocyte globulin.
abstract: Various antigens have been assessed for the ability to produce anti-human lymphocyte globulin(ALG). In our hands the most satisfactory antigen has proved to be cultured lymphoblasts. These are used to produce Behringwerke ALG(Pressimmune). A brief outline of problems in the large scale production of ALG and how these are overcome is given. The quality control checks for activity and safety are discussed.
mesh_terms: D000818:Animals; D000961:Antilymphocyte Serum / Q000592:standards; D004586:Electrophoresis; D000882:Haplorhini; D006736:Horses / Q000276:immunology; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D013678:Technology, Pharmaceutical
chemical_list: D000961:Antilymphocyte Serum