Common protective antigen (OEP) of Pseudomonas aeruginosa.
Prior immunization of mice with the protein moiety of the endotoxin (OEP) of Pseudomonas aeruginosa isolated by Homma and his associates [1, 2], can protect mice against infection with any of 21 standard strains belonging to Fisher's immunotypes and Homma's serotypes. It is also confirmed that there is found a significant protection in mice each injected with 0.1 ml of anti-OEP rabbit serum against challenge with each of 7 strains of Fisher's immunotypes. It has been revealed through the OEP-HA, agar gel diffusion and indirect fluorescent antibody tests that OEP is an antigen existing serologically in common in P. aeruginosa.
D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis*; D004731:Endotoxins / Q000276:immunology*; D005260:Female; D007106:Immune Sera; D007928:Lethal Dose 50; D051379:Mice; D011552:Pseudomonas Infections / Q000276:immunology; D011550:Pseudomonas aeruginosa / Q000276:immunology*; D011817:Rabbits
D000942:Antigens, Bacterial; D004731:Endotoxins; D007106:Immune Sera