Distribution and excretion of two chlorinated biphenyl isomers: 4-chlorobiphenyl and decachlorobiphenyl in lactating bovine.
One lactating cow was given a 4-chlorobiphenyl (50 mgm/kgm) as a single oral dose and was killed seven days postadministration. The presence of this compound was not detected in tissues, urine and milk. However, 28.9% of the total dose given was recovered in feces during the period of seven days postadministration. Another lactating cow received decachlorobiphenyl orally as single dose (50 mgm/kgm) and was also killed seven days postadministration. This totally chlorinated biphenyl was recovered at low concentrations from all tissues analyzed. The cumulative excretion into milk and feces accounted for 0.025 and 25.02% respectively. Decachlorobiphenyl was detected in urine.
D000273:Adipose Tissue / Q000032:analysis; D000284:Administration, Oral; D000818:Animals; D001713:Biphenyl Compounds / Q000378:metabolism*; D001923:Brain Chemistry; D002417:Cattle / Q000378:metabolism*; D002713:Chlorine / Q000378:metabolism; D005243:Feces / Q000032:analysis; D005260:Female; D007536:Isomerism; D007668:Kidney / Q000032:analysis; D007774:Lactation; D008099:Liver / Q000032:analysis; D008892:Milk / Q000032:analysis; D009132:Muscles / Q000032:analysis; D009206:Myocardium / Q000032:analysis; D011078:Polychlorinated Biphenyls / Q000008:administration & dosage / Q000378:metabolism*; D011247:Pregnancy
D001713:Biphenyl Compounds; D002713:Chlorine; D011078:Polychlorinated Biphenyls; C006983:4-chlorobiphenyl