[Biological and immunochemical properties of a complex of soluble antigens from N. meningitidis, serogroups A, B and C].
Complexes of surface soluble antigens were obtained in grown meningococci of serological groups A, B and C in fluid nutrient media. In studying the chemical composition and biological properties of these complexes released of the nutrient medium components it was revealed that they consisted of proteins, carbohydrates and lipids, possessed marked group-specific properties in the PHAT, were toxic (LD50 about 0.15 mg) and immunogenic.
D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis* / Q000633:toxicity; D002850:Chromatography, Gel; D003470:Culture Media; D004591:Electrophoresis, Polyacrylamide Gel; D006385:Hemagglutination Inhibition Tests; D007122:Immunoelectrophoresis; D007928:Lethal Dose 50; D051379:Mice; D009345:Neisseria meningitidis / Q000276:immunology*; D011817:Rabbits; D012703:Serotyping; D012995:Solubility
D000942:Antigens, Bacterial; D003470:Culture Media
Biologicheskie i immunokhimicheskie svoĭstva kompleksa rastvorimykh antigenov N. meningitidis serogrupp A, B i C