title: Prokaryotic DNA in nucleoid structure.
abstract: Recent studies of the structure of the bacterial nucleoid are reviewed. In the past 4 to 5 years results of electron microscopic and physical-chemical investigations of the isolated bacterial nucleoids have greatly advanced our understanding of this comparatively simple chromosome. Evidence for both long-range and short-range conformational organization of the packaged DNA has emerged, and preliminary characterization of the molecular interactions organizing this structure has been accomplished.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D001410:Bacillus megaterium; D002458:Cell Fractionation / Q000379:methods; D002876:Chromosomes, Bacterial / Q000032:analysis* / Q000648:ultrastructure; D004269:DNA, Bacterial / Q000032:analysis*; D004926:Escherichia coli; D008055:Lipids / Q000032:analysis; D008566:Membranes; D008954:Models, Biological; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D009698:Nucleoproteins / Q000032:analysis; D012329:RNA, Bacterial / Q000032:analysis; D014158:Transcription, Genetic
chemical_list: D000596:Amino Acids; D004269:DNA, Bacterial; D008055:Lipids; D009698:Nucleoproteins; D012329:RNA, Bacterial