Fat overload with a 10% soybean oil emulsion.
A 10% soybean oil emulsion (Intralipid) has been demonstrated to be an effective means of delivering an adequate caloric intake via a peripheral vein. This emulsion has generally been considered safe and free of significant complications. This is a report of a child who initially thrived on this intravenously administered fat emulsion, then suddenly developed a lifethreatening intolerance to the infusion, which appeared to be the "fat overload syndrome." This syndrome, seen frequently with earlier fat emulsions, has not been reported previously as a complication of the 10% soybean oil emulsion.
D004041:Dietary Fats / Q000009:adverse effects*; D004655:Emulsions; D006529:Hepatomegaly / Q000209:etiology; D006801:Humans; D006949:Hyperlipidemias / Q000209:etiology; D007223:Infant; D008297:Male; D010288:Parenteral Nutrition / Q000009:adverse effects*; D013025:Glycine max / Q000009:adverse effects*; D013163:Splenomegaly / Q000209:etiology; D013577:Syndrome
D004041:Dietary Fats; D004655:Emulsions