Monoclonal plasma cell population in the uterus.
The case of a 28-year-old female patient is presented. Heavy infiltration with plasma cells of uterine tissue removed by surgical currettage following an aborted pregnancy was detected by cytological and histological examination. Subsequent immunohistochemical studies revealed the monoclonal nature of these cells: intracellular immunoglobulin contained gamma- and lambda-chains exclusively. Since careful clinical examination produced no evidence in favor of multiple myeloma, these findings were tentatively interpreted to be compatible with the diagnosis of solitary plasmocytoma of the uterus.
D000026:Abortion, Habitual / Q000628:therapy; D000328:Adult; D003475:Curettage; D005260:Female; D006801:Humans; D007138:Immunoglobulin delta-Chains / Q000302:isolation & purification; D007142:Immunoglobulin gamma-Chains / Q000302:isolation & purification; D010950:Plasma Cells; D010954:Plasmacytoma / Q000175:diagnosis; D011247:Pregnancy; D014599:Uterus / Q000473:pathology*
D007138:Immunoglobulin delta-Chains; D007142:Immunoglobulin gamma-Chains