title: C3 polymorphism in polyacrylamide-gel electrophoresis.
abstract: C3 polymorphism in polyacrylamide-gel electrophoresis was identified by crossed immunoelectrophoresis using anti-C3/C3c-serum. Through ageing, treatment of sera with cobra venom factor, endotoxin or with neuramindase, polymorphic bands were seen also in a conversion product and antigenically attributed to C3c. Rare phenotypes were observable in native C3 and in C3c.
mesh_terms: D000818:Animals; D003176:Complement C3; D003165:Complement System Proteins; D004492:Edetic Acid / Q000494:pharmacology; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D009439:Neuraminidase / Q000494:pharmacology; D010641:Phenotype; D011110:Polymorphism, Genetic; D012910:Snake Venoms / Q000494:pharmacology
chemical_list: D003176:Complement C3; D012910:Snake Venoms; D003165:Complement System Proteins; D004492:Edetic Acid; D009439:Neuraminidase