title: Plasmid-determined resistance to erythromycin: comparison of strains of streptococcus faecalis and streptococcus pyogenes with regard to plasmid hmology and resistance inducibility.
abstract: Streptococcus faecalis strains DS-5 and Streptococcus pyogenes strain AC-1 both have a 17 million dalton plasmid that determines resistance to erythromycin, lincomycin, and vernamycin B(alpha). The results of deoxyribonucleic acid-deoxyribonucleic acid hybridization experiments indicate that the two plasmids are about 95% homologous. It was also shown that erythromycin resistance is inducible in AC-1 and constitutive in DS-5.
mesh_terms: D004352:Drug Resistance, Microbial; D013293:Enterococcus faecalis / Q000187:drug effects*; D004917:Erythromycin / Q000494:pharmacology*; D005111:Extrachromosomal Inheritance; D010957:Plasmids; D013297:Streptococcus pyogenes / Q000187:drug effects*
chemical_list: D004917:Erythromycin