Lymphoid cell dependent (K-cell) lysis of human erythrocytes sensitized with Rhesus alloantibodies.
An in vitro homologous system using human Rhesus alloantibodies and target erythrocytes labelled with 51Cr has been used to demonstrate the ability of normal peripheral blood lymphoid cells to lyse antibody-coated human red cells. The results obtained suggest that this type of mechanism may be relevant to certain haemolytic diseases in man.
D003601:Cytotoxicity Tests, Immunologic; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007518:Isoantibodies; D008214:Lymphocytes / Q000276:immunology*; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System
D007518:Isoantibodies; D012204:Rh-Hr Blood-Group System