Substitution of phosphate for oxalate in the study of calcium accumulation and release by cardiac microsomal fractions.
Phosphate-supported calcium uptake by guinea pig cardiac sarcoplasmic reticulum has been shown to exhibit a pattern different from that of oxalate-supported calcium uptake. Ionophore-induced calcium release has been demonstrated following phosphate-supported calcium uptake. Rat cardiac sarcoplasmic reticulum has been shown to differ from the guinea pig in its sensitivity to ionophore.
D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D000001:Calcimycin / Q000494:pharmacology; D002118:Calcium / Q000378:metabolism*; D006168:Guinea Pigs; D007700:Kinetics; D008861:Microsomes / Q000187:drug effects / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D010070:Oxalates / Q000494:pharmacology*; D010710:Phosphates / Q000494:pharmacology*; D051381:Rats; D013045:Species Specificity
D010070:Oxalates; D010710:Phosphates; D000001:Calcimycin; D002118:Calcium