[Deformation and orientation of sickle erythrocytes submitted to shearing forces].
Blood from patients with homozygous sickle cell anemia gives a "cross shaped" diffraction pattern, when submitted to shear stresses in the Ektacytometer. This pattern, which seems to be specific to these cells, is due to the existence of two populations of elliptical cells: one population (normal, deformable cells) aligned parallel to the direction of the flow, and the other (abnormal, rigid cells) perpendicular to the direction of the flow.
D000755:Anemia, Sickle Cell / Q000097:blood; D055592:Biophysical Phenomena; D001703:Biophysics; D004913:Erythrocytes, Abnormal; D006801:Humans; D012212:Rheology
Déformation et orientation des globules rouges falciformes soumis à des forces de cisaillement