Virus-induced modifications in the immunogenicity of red blood cells.
Studies of the immunogenicity of red blood cells (RBC) modified by interaction with viral agents show that measles hemagglutinin or adsorption-elution of influenza virus are able to induce modifications in the RBC immunogenicity, consisting in a depression of antibody synthesis and in a stimulation of the cell-mediated immune response. The modifications depend on the extent to which RBC-surface-bound viral antigens would mask the erythrocyte antigenic determinants.
D000818:Animals; D000917:Antibody Formation; D000918:Antibody Specificity; D004912:Erythrocytes / Q000276:immunology*; D000882:Haplorhini; D006389:Hemagglutinins, Viral; D007111:Immunity, Cellular; D008459:Measles virus; D009975:Orthomyxoviridae
D006389:Hemagglutinins, Viral