title: [Ultrastructure of Sertoli cells in male rats treated with "misulban" and stilbestrol].
abstract: The seminiferous tubulars of rats testis, subject to the action of Misulban during their foetal life, contain only Sertoli cells and constitute a good model for their study. From the ultrastructural point of view, these cells present several important mitochondria of tubular crest from, an abundant smooth endoplasmic reticulum, a Golgi apparatus well developed, a cytoplasm rich in ribosomes, Lipids droplets and intercellular junctions whose number increases with age. The administration of diethylstilbestrol, which inhibits gonadotropic and androgenic secretions reduces the signs of activity in the Sertoli cells.
mesh_terms: D000367:Age Factors; D000726:Androgen Antagonists; D000728:Androgens / Q000502:physiology; D000818:Animals; D002066:Busulfan / Q000494:pharmacology; D004054:Diethylstilbestrol / Q000494:pharmacology*; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D005854:Germ Cells / Q000187:drug effects; D006056:Golgi Apparatus / Q000648:ultrastructure; D006062:Gonadotropins / Q000037:antagonists & inhibitors / Q000502:physiology; D008297:Male; D008854:Microscopy, Electron; D008928:Mitochondria / Q000648:ultrastructure; D051381:Rats; D012270:Ribosomes / Q000648:ultrastructure; D012708:Sertoli Cells / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure
chemical_list: D000726:Androgen Antagonists; D000728:Androgens; D006062:Gonadotropins; D004054:Diethylstilbestrol; D002066:Busulfan
vernacular_title: Ultrastructure de la cellule de Sertoli chez le rat mâle soumis á l'action du "misulban" et du stilbestrol