A comparison of three commercially available antiseptics against opportunist gram-negative pathogens.
Two test methods, a skin replica test and the Kelsey Sykes test have been used to compare the efficacy of three antiseptics against three Gram-negative micro-organisms in an attempt to select the most suitable. The results of both tests showed that an antiseptic containing added ethylenediaminetetraacetic acid was superior to the other two. The skin test showed that this superiority was apparent in both the immediate and the persistant bactericidal activity of the antiseptic towards all three Gram-negative micro-organisms.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001645:Biguanides / Q000494:pharmacology*; D002593:Cetrimonium Compounds / Q000494:pharmacology*; D002710:Chlorhexidine / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects*; D005069:Evaluation Studies as Topic; D008826:Microbial Sensitivity Tests; D010636:Phenols / Q000494:pharmacology; D011514:Proteus vulgaris / Q000187:drug effects*; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D012882:Skin Tests; D013045:Species Specificity; D014992:Xylenes / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D001645:Biguanides; D002593:Cetrimonium Compounds; D010636:Phenols; D000644:Quaternary Ammonium Compounds; D014992:Xylenes; D002710:Chlorhexidine