[Effect of gliquidone and glibenclamide following oral administration].
Gliquidone shows a good blood sugar lowering effect over the wide dose range of 30-60 mg in fasting subjects with a healthy metabolism, in spite of the wide range. This behavior suggests that a good therapeutic application is to be expected in diabetics being treated with sulfonylureas.
D000284:Administration, Oral; D001786:Blood Glucose / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D005215:Fasting; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005905:Glyburide / Q000008:administration & dosage / Q000494:pharmacology*; D006593:Hexokinase; D006801:Humans; D007328:Insulin / Q000097:blood / Q000378:metabolism; D000078790:Insulin Secretion; D012146:Rest; D013453:Sulfonylurea Compounds / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D013453:Sulfonylurea Compounds; D006593:Hexokinase; D005905:Glyburide
Wirkung von Gliqudon und Glibenclamid nach oraler Anwendung