title: [Study of sinus node function. Preliminary results].
abstract: Direct exploration of the sinus node remains experimental. Indirect techniques have been put forward to assess the sinus function in man: high frequency atrial pacing; premature atrial pacing; pharmacodynamic tests using atropin and isoproterenol injection. 68 patients were so explored: in 10 of them were ECG signs suggestive of "sinus disease" or "atrium disease" (group I); 14 subjects had only a sinus bradycardia with a rate of 55/mn or below (group II); in 16 cases, the ECG tracing was normal, but there was the notion of paroxysmal tachycardia or various disturbances (group IIIa); finally, in 28 cases the ECG demonstrated atrio-ventricular or inter-ventricular conduction disturbances (group IIIb). The preliminary results reported here should be interpreted carefully; nevertheless, correlation of the data obtained by the various techniques used, seems to be able to allow a correct assessment of sinus automatism, and of sino-atrial conduction.
mesh_terms: D000328:Adult; D000368:Aged; D001146:Arrhythmia, Sinus / Q000503:physiopathology; D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D001285:Atropine; D001919:Bradycardia / Q000503:physiopathology; D004558:Electric Stimulation; D005260:Female; D006327:Heart Block / Q000503:physiopathology; D006801:Humans; D007545:Isoproterenol; D008297:Male; D008875:Middle Aged; D012849:Sinoatrial Node / Q000187:drug effects / Q000503:physiopathology*; D013614:Tachycardia, Paroxysmal / Q000503:physiopathology
chemical_list: D001285:Atropine; D007545:Isoproterenol
vernacular_title: Etude de la fonction sinusale. Résultats préliminaires