title: [Treatment of hemophilia A with actor VIII concentrate in urological operations and injuries of the urinary tract].
abstract: A congenital tencency to bleeding can nowadays be successfully treated by substitution of the missing clotting factors. One patient with a slight hemophilia A had a renal calculus removed without complications by pyelotomy, using an antihemophilic Factor VIII concentrate. A 16-year-old boy with a severe form of hemophilia A suffered a renal trauma with retroperitoneal hemorrhage. He was treated conservatively with Factor VIII concentrate and partial function of the kidney was retained. Substitution therapy for operative or conservative procedures and the requirements and expense are discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D001027:Aortography; D003365:Costs and Cost Analysis; D005169:Factor VIII / Q000009:adverse effects / Q000302:isolation & purification / Q000627:therapeutic use*; D006467:Hemophilia A / Q000188:drug therapy*; D006470:Hemorrhage / Q000517:prevention & control*; D006506:Hepatitis A / Q000209:etiology; D006801:Humans; D007668:Kidney / Q000293:injuries; D008297:Male; D014551:Urinary Tract / Q000293:injuries; D014567:Urography; D014570:Urologic Diseases / Q000601:surgery*
chemical_list: D005169:Factor VIII
vernacular_title: Die Therapie der Hämophilie A mit Faktor-VIII-Konzentrat bei urologischen Operationen und Harnwegsverletzungen