An improved technique in the diagnosis of pemphigus.
Pemphigus lesions are characterized by intraepithelial bullae. This phenomenon is used in a new practical procedure for obtaining specimens of diseased epithelium with a minimum of discomfort to the patient. This procedure makes it possible to demonstrate in vivo bound immunoglobulins in the epithelium without taking an ordinary biopsy for making the diagnosis of pemphigus.
D001706:Biopsy / Q000379:methods*; D006801:Humans; D010392:Pemphigus / Q000175:diagnosis* / Q000473:pathology