title: Cytoenzymologic activities of some oxidroeductases and alkaline phosphatase of leucocytes in Basedow, Cushing and Addison diseases.
abstract: Leukocytes, approached by histoenzymological methods for demonstration of dihydrofolate dehydrogenase, NADH2-diaphorase, lactate dehydrogenase and alcaline phosphatase activities, provided information about the impaired metabolic balance of thyrotoxicosis, Cushing and Addison diseases. The most relevant variations were found in thyrotoxicosis, the most sensitive enzyme was dihydrofolate dehydrogenase and the less sensitive was alcaline phosphatase. The neutrophils and lymphocytes had more evident enzymic variations.
mesh_terms: D000224:Addison Disease / Q000097:blood / Q000201:enzymology*; D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood*; D003480:Cushing Syndrome / Q000097:blood / Q000201:enzymology*; D005260:Female; D006111:Graves Disease / Q000097:blood / Q000201:enzymology*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007962:Leukocytes / Q000201:enzymology*; D008214:Lymphocytes / Q000201:enzymology; D008297:Male; D008875:Middle Aged; D009252:NADPH Dehydrogenase / Q000097:blood; D009504:Neutrophils / Q000201:enzymology; D010088:Oxidoreductases / Q000097:blood*; D013762:Tetrahydrofolate Dehydrogenase / Q000097:blood
chemical_list: D010088:Oxidoreductases; D007770:L-Lactate Dehydrogenase; D013762:Tetrahydrofolate Dehydrogenase; D009252:NADPH Dehydrogenase; D000469:Alkaline Phosphatase