[Study of proteins binding radioactive indium in vivo].
After in vivo infusion, radio-active indium is fixed by liver and bone marrow, but more slowly and less completely than iron. It does not incorporate to haem. It is found as labelled ferritin in the liver, after the fifth day. In the bone marrow, indium is almost exclusively found as labelled transferrin; several arguments suggest the intra-cellular site of the labelled protein. Using indium may enable a better knowledge of the intermediary iron pools.
D000818:Animals; D001853:Bone Marrow / Q000378:metabolism*; D001854:Bone Marrow Cells; D002352:Carrier Proteins / Q000378:metabolism*; D005293:Ferritins / Q000378:metabolism; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007204:Indium / Q000097:blood / Q000378:metabolism*; D007501:Iron / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D051381:Rats; D013997:Time Factors; D014168:Transferrin / Q000378:metabolism
D002352:Carrier Proteins; D006454:Hemoglobins; D014168:Transferrin; D007204:Indium; D005293:Ferritins; D007501:Iron
Etude des protéines fixant in vivo l'indium radio-actif