The homologues of rabbit b-allotypes on hare immunoglobulin light chains: an evolutionary puzzle.
Most alloantisera directed against the rabbit allotypes b4, b5, and b6 cross-reacted with hare IgG. The determinants recognized by antisera against the three allotypes were shown to reside on the same hare L chains. Hare immunoglobulins, when injected into b4, b5, or b9 rabbits, elicited the formation of antibodies which reacted with hare IgG and cross-reacted with those rabbit allotypes (except b9) absent from the recipient. The anti-b9 antisera tested lacked reactivity with hare IgG.
D000818:Animals; D000918:Antibody Specificity; D000937:Antigen-Antibody Reactions; D005075:Biological Evolution; D003429:Cross Reactions; D007106:Immune Sera; D007074:Immunoglobulin G; D007147:Immunoglobulin Light Chains; D007519:Isoantigens; D007793:Lagomorpha; D011817:Rabbits; D013045:Species Specificity
D007106:Immune Sera; D007074:Immunoglobulin G; D007147:Immunoglobulin Light Chains; D007519:Isoantigens