[Acute facial mucormycosis in a diabetic subject. Successful treatment with Amphotericin B].
A 29 year old male, admitted with diabetic keto-acidosis, was found to have rhinocerebral phycomycosis (mucormycosis) involving the left eye and the left hard palate with perforation into the maxillary antrum. Despite late diagnosis, full recovery was obtained following intravenous Amphotericin B (total dose : 3.015 gm in 4 months) and extensive surgery (debridement and unilateral eye enucleation). The circumstances of onset of the disease and its clinical characteristics are discussed; the main features of its management are analyzed.
D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use*; D016883:Diabetic Ketoacidosis / Q000150:complications*; D005128:Eye Diseases / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008443:Maxillary Sinus / Q000382:microbiology; D009091:Mucormycosis / Q000150:complications / Q000188:drug therapy*; D010159:Palate; D010254:Paranasal Sinus Diseases / Q000188:drug therapy
D000666:Amphotericin B
Mucormycose du massif facial chez le diabetique. A propos d'un cas traité avec succès par amphotéricine B