[Cure of experimental hyperlactatemia and lactic acidosis by sodium dichloroacetate].
Sodium dichloroacetate prevents and fights against the severe hyperlactatemia and lactic acidosis induced by phenformin, intense muscular work, hypoxia and by adrenalin perfusion. The beneficent effects of sodium dichloroacetate and insulin are additive.
D000085:Acetates / Q000627:therapeutic use*; D000138:Acidosis / Q000139:chemically induced / Q000150:complications / Q000188:drug therapy*; D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D004837:Epinephrine; D000860:Hypoxia; D007328:Insulin / Q000627:therapeutic use; D007773:Lactates / Q000378:metabolism*; D010629:Phenformin; D005082:Physical Exertion
D000085:Acetates; D007328:Insulin; D007773:Lactates; D010629:Phenformin; D004837:Epinephrine
Correction de l'hyperlactatémie et de l'acidose lactique expérimentales par le dichloroacétate de sodium