title: The effect of fat emulsion (Intralipid) on essential fatty acid deficiency in infants receiving intravenous alimentation.
abstract: Thirteen infants who received IVA in four different ways were studied. The serum fatty acid composition of the infants who received fat-free IVA showed EFA deficiency within 1 wk. This deficiency was cured by administering fat emulsion which accounted for 4% of the total caloric content of the infusate. Fat emulsion which accounted for 2% of the total calories neither improved nor prevented EFA deficiency. This means that intravenous fat emulsion, Intralipid, which accounted for 2% of the total calories as linoleic acid, still satisfies the essential fatty acid requirement.
mesh_terms: D002675:Child, Preschool; D003677:Deficiency Diseases / Q000188:drug therapy; D004655:Emulsions; D005228:Fatty Acids, Essential / Q000032:analysis / Q000172:deficiency*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008041:Linoleic Acids / Q000032:analysis / Q000627:therapeutic use*; D008055:Lipids / Q000008:administration & dosage; D008297:Male; D010288:Parenteral Nutrition / Q000009:adverse effects*
chemical_list: D004655:Emulsions; D005228:Fatty Acids, Essential; D008041:Linoleic Acids; D008055:Lipids