title: Immunochemical analysis of an unusual cell wall polysaccharide from animal coagulase-positive staphylococci. 2. Probable structure based on chemical and serological studies.
abstract: The teichoic acid of polysaccharide P (poly P) contains glycerol, glucose and phosphate. Hydrofluoric acid and alkali hydrolysates contain glycerol 1-phosphate, glycerol diphosphate, and glucose 1-phosphate, but no glucosyl-glycerol fragments. Glucose and the serological activity of poly P were destroyed by periodate oxidation. Interaction with concanavalin A showed that the glucose is in alpha-configuration and that the hydroxyl groups at positions 3, 4 and 6 are unsubstituted. Most probably, the poly P teichoic acid is a polymer containing a repeating unit in which glycerol 1-phosphate is attached to the 2-position on alpha-D-glucose 1-phosphate.
mesh_terms: D000468:Alkalies; D002473:Cell Wall / Q000032:analysis*; D011232:Chemical Precipitation; D003030:Coagulase; D003208:Concanavalin A; D005947:Glucose / Q000032:analysis; D005990:Glycerol / Q000032:analysis; D006858:Hydrofluoric Acid; D006868:Hydrolysis; D005779:Immunodiffusion; D010710:Phosphates / Q000032:analysis; D011135:Polysaccharides, Bacterial / Q000032:analysis*; D013211:Staphylococcus aureus / Q000032:analysis*; D013682:Teichoic Acids
chemical_list: D000468:Alkalies; D003030:Coagulase; D010710:Phosphates; D011135:Polysaccharides, Bacterial; D013682:Teichoic Acids; D003208:Concanavalin A; D005947:Glucose; D005990:Glycerol; D006858:Hydrofluoric Acid