[Production of a dialysable transfer factor of cell mediated immunity by lymphoblastoid cells in continuous proliferation].
Four lymphoblastoid cell lines tested in this work contain normally a dialysable moiety having by ultraviolet spectroscopy, column chromatography (Biogel P 10) and chemically the same properties than human dialysable Transfer Factor (TFd), but unable to transfer cell mediated immune response against common antigens. Two of them are able to do so after incubation with minimal amounts of TFd. Production of a molecule identical to human TFd is possible in some lymphoblastoid cell lines after induction with TFd.
D000818:Animals; D002460:Cell Line; D002850:Chromatography, Gel; D000882:Haplorhini; D006801:Humans; D007111:Immunity, Cellular; D007428:Intradermal Tests; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000378:metabolism*; D010215:Papio; D051381:Rats; D011917:Rats, Inbred Lew; D013056:Spectrophotometry, Ultraviolet; D014165:Transfer Factor / Q000096:biosynthesis / Q000302:isolation & purification
D014165:Transfer Factor
Production de facteur de transfert dialysable de l'immunité à médiation cellulaire par des cellules lymphoblastoïdes en prolifération continue