title: Tetracycline-induced pleural symphysis for recurrent hydrothorax complicating cirrhosis. A new approach to treatment.
abstract: Two patients with cirrhosis and ascites complicated by extensive unilateral pleural transudates refractory to therapy with dietary sodium restriction, diuretics, and repeated thoracentesis were successfully managed by tetracycline-induced pleural symphysis. The intrapleural instillation of this antibiotic prevented the recurrence of the effusion and substantially relieved the patients' symptoms with minimal undesirable side effects.
mesh_terms: D005260:Female; D006801:Humans; D006876:Hydrothorax / Q000188:drug therapy* / Q000209:etiology; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008722:Methods; D008875:Middle Aged; D010994:Pleura; D010996:Pleural Effusion / Q000188:drug therapy* / Q000209:etiology; D012008:Recurrence; D013752:Tetracycline / Q000627:therapeutic use*
chemical_list: D013752:Tetracycline