title: [Etiopathogenetic approach to the treatment of viral-bacterial pneumonias].
abstract: The efficacy of aerosols of leukocytal interferon used in complex with antibacterial and other medicamentous agents was studied during influenza epidemic in 1975 due to Port-Chalmers virus of influenza A with increased numbers of viral-bacterial pneumonia. The viral-sta-phylococcal etiology of the infection was confirmed in 80 per cent of the cases under stationary conditions. Various microorganism and most often Staph aureus were isolated in addition to the viruses from the patient's sputum and washings and their antibioticograms were determined. The studies showed that the complex treatment of the patients with virologically and serologically confirmed diagnosis of the disease resulted in decreased duration of the disease, less pronounced intoxication and more rapid resorption of the changes in the lung tissue.
mesh_terms: D000336:Aerosols; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D006801:Humans; D009980:Influenza A virus / Q000276:immunology; D007251:Influenza, Human / Q000150:complications; D007372:Interferons / Q000627:therapeutic use; D007711:Klebsiella pneumoniae / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009031:Moscow; D011014:Pneumonia / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology; D011024:Pneumonia, Viral / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013210:Staphylococcus / Q000187:drug effects
chemical_list: D000336:Aerosols; D000900:Anti-Bacterial Agents; D007372:Interferons
vernacular_title: Etiopatogeneticheskiĭ podkhod k lecheniiu virusno--bakterial'nykh pnevmoniĭ