title: 99Tcm-DTPA for the measurement of glomerular filtration rate.
abstract: Comparison of the blood clearances of 51Cr-EDTA and 99Tcm-Sn-DTPA, in a series of 45 patients with a wide range of glomerular filtration rates, showed that there was a good correlation between the estimates of G.F.R. obtained using the two chelates simultaneously. The single-injection, single-exponential method of G.F.R. estimation was used, with a correction factor of 0.964 for 99Tcm-DTPA, which gave a relationship of G.F.R.Cr = 2.3+G.F.R.Tcml/min with a correlation coefficient of 0.99. 99Tcm-DTPA is a suitable agent for the estimation of glomerular filtration rate.
mesh_terms: D002860:Chromium Radioisotopes; D004492:Edetic Acid; D005919:Glomerular Filtration Rate; D006801:Humans; D004369:Pentetic Acid; D013667:Technetium
chemical_list: D002860:Chromium Radioisotopes; D013667:Technetium; D004369:Pentetic Acid; D004492:Edetic Acid