[The labeling of human lymphoblastoid cells cultivated in media enriched with nickel sulfate].
The tritiated thymidine labeling of the established human normal cell line LHN 13 suggests that the DNA synthesis stimulation by the nickel sulphate is a function of nickel sulphate concentrations and a function of time. The low and high concentrations play the same role and this role is different from that played by medium concentrations. So, a band of stimulating concentrations appears that could be the result of blocked reactions and coupled oscillators.
D004247:DNA / Q000096:biosynthesis*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects* / Q000378:metabolism; D009532:Nickel / Q000494:pharmacology*; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors
D009532:Nickel; D004247:DNA; D013936:Thymidine
Etude de l'index de marquage de cellules lymphoblastoïdes humaines cultivées en milieux enrichis de sulfate de nickel