Comparison of serum IgE determination by radioimmunoassay and by single radial immunodiffusion.
Two commercially available methods of total serum IgE determination have been evaluated, viz: the radioimmunosorbent test (RIST) and the assay by single radial immunodiffusion (RID). RIST was found a suitable and rapid method for the wide range of IgE concentrations to be expected in the sera of an allergic population. The RID method has a lower limit of detection of about 1000 I.U./ml; over this value, both techniques provided statistically correlated results. However, for technological reasons RID was considered less suitable for routine application.
D001249:Asthma / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology; D005779:Immunodiffusion / Q000379:methods; D007073:Immunoglobulin E / Q000032:analysis*; D011863:Radioimmunoassay / Q000379:methods
D007073:Immunoglobulin E