[Cycloheximide has no effect on the conditioning of the uterus for implantation by certain ovarian steroids].
Cycloheximide was unable to induce or inhibit the appearance of the refractory state to decidualization which is normally obtained by a small dose of oestrogen given to the progesterone-dominated uterus. Neither was this inhibitor capable of preventing progesterone from sensitizing the uterus to decidualizing stimuli. These results suggest that certain effects of luteal steroids in endometrial cells do not depend on RNA translation.
D000818:Animals; D002369:Castration; D003513:Cycloheximide / Q000494:pharmacology*; D003656:Decidua / Q000187:drug effects; D010064:Embryo Implantation / Q000187:drug effects*; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D011247:Pregnancy; D011374:Progesterone / Q000494:pharmacology*; D014176:Protein Biosynthesis; D051381:Rats; D014599:Uterus / Q000187:drug effects* / Q000378:metabolism
D011374:Progesterone; D004958:Estradiol; D003513:Cycloheximide
Inactivité de la cycloheximide sur certains effets des stéroides ovariens responsables du conditionnement de l'utérus à la nidation