Identification of coreplicating chromosomal sectors in Bacillus subtilis by nitrosoguanidine-induced comutation.
The simultaneous replication of four regions of dichotomously replicating chromosomes of Bacillus subtilis has been detected by means of nitrosoguanidine-induced comutation. The map distance between successive rounds of replication has been measured as one-half a replicative arm in cells growing exponentially in rich medium.
D001412:Bacillus subtilis / Q000378:metabolism*; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial / Q000378:metabolism*; D004261:DNA Replication; D008040:Genetic Linkage; D008769:Methylnitronitrosoguanidine / Q000494:pharmacology*; D009153:Mutagens; D009154:Mutation; D009604:Nitrosoguanidines / Q000494:pharmacology*; D011687:Purines / Q000378:metabolism; D014161:Transduction, Genetic
D009153:Mutagens; D009604:Nitrosoguanidines; D011687:Purines; D008769:Methylnitronitrosoguanidine