title: The need for standardization of allergenic extracts utilized in humans for diagnosis and therapy.
abstract: It seems clear that the results of allergenic immunotherapy depend on the value of the allergens available. In our opinion the following points should be discussed and clarified : the choice of allergenic substances, potency units, therapeutic dilutions, delayed action allergens, active antibodies, standardization of allergens of well-determined biological species (plants, mould, microscopic fungi, microbial germs, house dust, pollens, parasites), standardization of adjuvants, standardization of allergen dispensation, solvents used for dilutions, solutions used for dilutions, preservatives, etc. A great deal of work is involved and should be undertaken without delay on an international scale.
mesh_terms: D000485:Allergens / Q000592:standards*; D001419:Bacteria / Q000276:immunology; D005069:Evaluation Studies as Topic; D005512:Food Hypersensitivity; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D005779:Immunodiffusion; D007422:Intestines / Q000276:immunology; D008168:Lung / Q000276:immunology; D008722:Methods; D011058:Pollen; D011863:Radioimmunoassay; D012867:Skin / Q000276:immunology
chemical_list: D000485:Allergens