[The effects of different amino acids and structural analogues on the penetration of L-tryptophan in mouse brain in vivo and in vitro].
Various amino-acids and substituted tryptophane derivatives inhibit the penetration of tryptophane in mice brain slices. Their inhibitory effect is rapidly neutralized in vivo by a perpheral mechanism, including the binding of tryptophane to circulating serumalbumins.
D000596:Amino Acids / Q000494:pharmacology*; D000818:Animals; D003864:Depression, Chemical; D051379:Mice; D012709:Serum Albumin / Q000378:metabolism; D014364:Tryptophan / Q000031:analogs & derivatives* / Q000097:blood / Q000378:metabolism*
D000596:Amino Acids; D012709:Serum Albumin; D014364:Tryptophan
Effets de divers acides aminés et d'analogues structuraux sur la pénétration du L-tryptophanne dans le cerveau des souris in vivo et in vitro