Immediate hypersensitivity in patients with cystic fibrosis.
Twenty-three out of thirty patients with cystic fibrosis gave strong immediate skin hypersensitivity reaction to a wide variety of allergens. Seventy-five per cent of these had a markedly elevated serum IgE concentration whereas those patients who had negative Type 1 immediate skin reactions also had normal levels of serum IgE. The sputum of those patients with immediate skin reactivity also had positive precipitins to a variety of antigens.
D000485:Allergens / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000276:immunology*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D005779:Immunodiffusion; D007073:Immunoglobulin E / Q000032:analysis; D007223:Infant; D011233:Precipitin Tests; D012882:Skin Tests
D000485:Allergens; D007073:Immunoglobulin E