title: A renin-like activity in pineal gland and hypophysis.
abstract: Using Boucher micromethod for determining renin activity in the rat pineal gland and hypophysis tissues, before and after NaCl 10% i.v. administration, the normal rats showed an average value of 96.8 +/- 21 ng Ang/g/h at the hypophysis level, and 325 +/- 66 ng Ang/g/h in epiphysis. In rats previously treated with 1--1.5 ml. NaCl 10% i.v., a more reduced renin-like activity was found both in hypophysis and epiphysis, that is 36.5 +/- 13 ng Ang/g/h and 144.5 +/- 38 Ang/g/h, respectively. In keeping with the previous data regarding the drinking and ADH-releasing effects of angiotensin, the obtained results plead for a possible participation of the cerebral glandular tissue renin in the self-regulating of the hydroelectrolytic balance.
mesh_terms: D000818:Animals; D001933:Brain Stem / Q000032:analysis; D002540:Cerebral Cortex / Q000032:analysis; D007031:Hypothalamus / Q000032:analysis; D007275:Injections, Intravenous; D010870:Pineal Gland / Q000032:analysis*; D010902:Pituitary Gland / Q000032:analysis*; D051381:Rats; D012083:Renin / Q000032:analysis*; D012965:Sodium Chloride / Q000008:administration & dosage / Q000494:pharmacology
chemical_list: D012965:Sodium Chloride; D012083:Renin