title: Impairment of platelet adhesiveness and platelet factor 3 activity in cyanotic congenital heart disease.
abstract: In 33 children with cyanotic congenital heart disease the platelet function has been studied. The most significant changes were reduced platelet adhesiveness to glass and impaired availability of platelet factor 3 in nearly 50% of the patients. Although clot retraction was poor in 84% of them, thrombocytopenia and prolonged bleeding time were not significant features.
mesh_terms: D001779:Blood Coagulation Factors; D001780:Blood Coagulation Tests / Q000295:instrumentation; D002648:Child; D002675:Child, Preschool; D006330:Heart Defects, Congenital / Q000097:blood*; D006801:Humans; D007223:Infant; D008297:Male; D010973:Platelet Adhesiveness; D010977:Platelet Factor 3
chemical_list: D001779:Blood Coagulation Factors; D010977:Platelet Factor 3