Lung antiproteinase: a potential defense against emphysema development.
A heat-labile, high molecular weight anti-elastase has been obtained from the peripheral air spaces by saline lavage. This antiproteinase appears to be different from known serum inhibitors. The lung antiproteinase prevents elastase-induced experimental emphysema.
D000818:Animals; D004285:Dogs; D004646:Emphysema / Q000201:enzymology / Q000517:prevention & control*; D000882:Haplorhini; D008168:Lung / Q000201:enzymology; D010196:Pancreatic Elastase / Q000037:antagonists & inhibitors*
D010196:Pancreatic Elastase