[The phenotype Hp O in several African and Central American populations].
This work shows the higher probability for some individuals of having Hp O phenotype: that is, children under twelve, and individual carriers of haemoglobin S (haemoglobin D carriers do not present this characteristic). This observation appears as a confirmation of the hypotheses explaining Hp O phenotype as a consequence of haemolytic anaemia. Besides, the test of two genetic models taking into account both Hp O and Hp21 M phenotypes leads to strong difficulties due to a certain irregularity of "haptoglobin" genetic system.
D000367:Age Factors; D000743:Anemia, Hemolytic / Q000097:blood; D002488:Central African Republic; D002648:Child; D005828:Genetics, Population; D006172:Guyana; D006242:Haptoglobins / Q000172:deficiency*; D006451:Hemoglobin, Sickle / Q000032:analysis; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008302:Mali; D010641:Phenotype; D012675:Senegal
D006242:Haptoglobins; D006451:Hemoglobin, Sickle; D006454:Hemoglobins
Le phénotype Hp O dans quelques populations d'Afrique et d'Amérique centrale.