title: [Sebaceous gland tumors in dogs].
abstract: Histologically were investigated 37 cases of neoplastic growths and 2 cases of hyperplasia in canine sebaceous glands. From this number 24 tumours of circumanal glands (20 adenomas and 4 carcinomas) and 13 tumours of sebaceous glands in extraanal localization were found. The average age of affected dogs was 9 years. In the neoplastic tissue of circumanal adenomas three differentiation degrees of sebaceous cells were identified. Biological behaviour is favourable, tumours destructured the tissue only topically. Malignant neoplasias consisted of tumorously proliferated, lowly differentiated sebaceous cells. Tumours observed in the ear and external ear canal are histologically similar to human cutaneous sebaceous gland adenomas and therefore from the viewpoint of comparative oncology they are important. In therapy, surgical extirpation is applied with possible estrogen combination.
mesh_terms: D000236:Adenoma / Q000473:pathology / Q000662:veterinary; D000818:Animals; D002277:Carcinoma / Q000473:pathology / Q000662:veterinary; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D012626:Sebaceous Gland Neoplasms / Q000473:pathology / Q000662:veterinary*