title: [A tissue specific antigen in rats with malignancies in vitro].
abstract: By means of a semiquantitative antigenic analysis in the reaction of precipitation in agar with the use of a monospecific serum,  obtained by the authors, dynamical changes have been studied in the content of the tissue-specific antigen in cells of subcutaneous connective tissue in rats: in the original and tripsinzed tissues, in 3, 6, 16-day and 1--2--3 month and malignized cultures, as well. It was found that at the 3, 11--13 day and then in 2--3 months of explantation there was a decrease in the content of the tissue-specific antigen, that is positively correlated with the degree of cell differentiation.
mesh_terms: D000818:Animals; D000941:Antigens; D000951:Antigens, Neoplasm; D002384:Catalysis; D002454:Cell Differentiation; D002471:Cell Transformation, Neoplastic; D046508:Culture Techniques; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D009372:Neoplasms, Connective Tissue / Q000276:immunology*; D009928:Organ Specificity; D051381:Rats; D013997:Time Factors; D014357:Trypsin
chemical_list: D000941:Antigens; D000951:Antigens, Neoplasm; D014357:Trypsin
vernacular_title: Tkanespetsificheskiĭ antigen u krys pri malignizatsii in vitro