Postmortem fixation of human lungs for electron microscopy.
A simple method of lung tissue preservation immediately post mortem by transthoracic injection of stained glutaraldehyde is described. By repetitive injections at varying time intervals after death it can be shown qualitatively and quantitatively by morphometry that normal lung tissue shows good preservation for at least 8 hours, whereas autolysis sets in shortly after death in diseased lungs.
D001329:Autolysis; D001344:Autopsy; D005976:Glutaral; D006652:Histological Techniques; D006801:Humans; D008168:Lung / Q000473:pathology*; D008722:Methods; D008854:Microscopy, Electron; D013997:Time Factors; D014021:Tissue Preservation
D005976:Glutaral