[Results of long term use of a low dose estroprogestatif in diabetics and "high risk" women].
The authors study the long term effects (3 to 30 months) on carbohydrate metabolism of an oral contraceptive containing lowdoses of ethinyloestradiol (0.03 mg) and 0.15 mg of dnorgestrel. The study was carried out in 19 women with diabetes and/or high risk - 5 were on insulin, 6 had asymptomatic, latent or potential diabetes and 8 were obeses. In the insulin dependent group, no changes were seen in blood glucose levels. Insulin doses were the same before and during treatment. In the asymptomatic diabetes group, no modification in carbohydrate metabolism occured. Glucose tolerance tests which were abnormal before treatment became normal under treatment. This finding is discussed. In the obese group, carbohydrate tolerance remained normal during treatment. The low dose of ethinyloestradiol in this "pill" is probably responsible for the absence of diabetogenic side-effects. It would thus appear possible to use such an oral contraceptive in diabetics (overt or asymptomatic) when necessary. However the customary regular surveillance is required.
D001786:Blood Glucose / Q000032:analysis; D003276:Contraceptives, Oral; D003920:Diabetes Mellitus; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008134:Long-Term Care; D009765:Obesity; D012306:Risk
D001786:Blood Glucose; D003276:Contraceptives, Oral
Résultats de l'utilisation prolongée d'un estroprogestatif faiblement dosé chez des diabétiques et des femmes à "haut risque"