Increased disaccharidase activity in human diabetics.
Disaccharidase activity has been shown to be increased in human diabetics. Diabetics controlled on diet therapy showed no change in disaccharidase activity while two diabetics controlled on insulin or insulin-producing drug, glibenclamide, showed a fall in disaccharidase values toward normal. Possible causes for the increased disaccharidase activity in diabetes are discussed.
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D003920:Diabetes Mellitus / Q000178:diet therapy / Q000188:drug therapy / Q000201:enzymology*; D004186:Disaccharidases / Q000378:metabolism*; D005243:Feces / Q000032:analysis; D005260:Female; D005696:Galactosidases / Q000378:metabolism; D005959:Glucosidases / Q000378:metabolism; D005905:Glyburide / Q000627:therapeutic use; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D007583:Jejunum / Q000201:enzymology*; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D013393:Sucrase / Q000378:metabolism
D001786:Blood Glucose; D007328:Insulin; D004186:Disaccharidases; D005696:Galactosidases; D005959:Glucosidases; D013393:Sucrase; D005905:Glyburide