Induction of subcapsular cataracts in aniridic vervet monkeys by echothiophate.
Four surgically aniridic vervet monkeys with clear lenses received topical echothiophate iodide unilaterally daily for eight weeks. The opposite eyes received a control solution without echothiophate. All the echothiophate-treated eyes developed subcapsular lens opacities sttongly resembling those attributed to echothiophate in humans. The lenses in the control eyes remained clear.
D000818:Animals; D002386:Cataract / Q000139:chemically induced*; D002522:Chlorocebus aethiops; D004456:Echothiophate Iodide / Q000009:adverse effects*; D005260:Female; D000882:Haplorhini; D007498:Iris / Q000502:physiology
D004456:Echothiophate Iodide