title: Mammalian carbonic anhydrase isozymes: evidence for a third locus.
abstract: Starch gel electrophoretic patterns of carbonic anhydrase (CA) isozymes were examined from tissue extracts of sheep, mice, rabbits, and chickens. In addition to the widely distributed and extensively studied B and C isozymes, an additional isozyme (called CA-A) was observed, which was predominantly localized in muscle tissue. Immunochemical studies showed the A isozyme to be homologous with CA-B. Developmental and tissue distribution analyses suggested that a third locus (A) is involved in carbonic anhydrase synthesis in mammals.
mesh_terms: D000818:Animals; D002256:Carbonic Anhydrases / Q000378:metabolism*; D002645:Chickens; D007527:Isoenzymes / Q000378:metabolism*; D051379:Mice; D008815:Mice, Inbred Strains; D009132:Muscles / Q000201:enzymology; D011817:Rabbits; D012756:Sheep
chemical_list: D007527:Isoenzymes; D002256:Carbonic Anhydrases