Diabetic complications in a patient with coexisting anterior hypopituitarism.
We present a patient who developed insulin-requiring diabetes several years after the onset of symptoms of anterior hypopituitarism. It is likely that the hypopituitarism protected him against the development of diabetic retinopathy and glomerular basement membrane thickening but not against neuropathy and atheroma. The significance of this in relation to the growth-hormone-microangiopathy hypothesis is discussed.
D000368:Aged; D001161:Arteriosclerosis / Q000209:etiology; D001485:Basement Membrane / Q000473:pathology; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000473:pathology; D003925:Diabetic Angiopathies / Q000209:etiology; D016883:Diabetic Ketoacidosis / Q000150:complications; D003929:Diabetic Neuropathies / Q000209:etiology; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D007018:Hypopituitarism / Q000150:complications* / Q000473:pathology; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D010903:Pituitary Gland, Anterior
D013006:Growth Hormone