Airsacculitis in the baboon.
A baboon (Papio anubis) that had been given opiate compounds through an indwelling catheter developed mucopurulent airsacculitis. After a prolonged course, the infection was eventually controlled by medical and surgical means. Air-sac involvement, though rarely reported in nonhuman primates, appeared frequently in the group of baboons to which this subject belonged--all of which were being treated experimentally with opiates. Proposed explanations for this unusual incidence included the propensity of opiates to induce a histamine response, almost continuous contamination of pathogenic bacteria in the indwelling catheters, and a suggested anatomic predisposition of the baboon larynx to drain secretions into the air sac.
D000400:Air Sacs / Q000601:surgery; D000818:Animals; D001982:Bronchial Diseases / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D002701:Chloramphenicol / Q000627:therapeutic use; D000882:Haplorhini; D007249:Inflammation; D008297:Male; D008992:Monkey Diseases / Q000188:drug therapy / Q000601:surgery; D010215:Papio; D013754:Tetracyclines / Q000627:therapeutic use
D013754:Tetracyclines; D002701:Chloramphenicol