[Comparative studies on placenta specific proteins in man and subhuman primates (author's transl)].
It is shown that in placentae and partly also in sera from pregnant monkeys (chimpanzee, baboon, rhesus monkey and cynomolgus) proteins occur which are immunochemically related to the human placental specific antigens HPL (human placental locatogen), SP1 (pregnancy specific beta1-glycoprotein), PP5 (placental protein 5) and HSAP (heat stable alkaline phosphatase). The immunochemical and physico-chemical properties of these monkey proteins are compared with those of the corresponding human proteins using gel diffusion test, immuno-electrophoresis, gel filtration and polyacrylamide gel electrophoresis. These antigens also have been localized in the tissue of human and monkey (cynomolgus) placentae by the immunofluorescent technique.
D000469:Alkaline Phosphatase / Q000032:analysis; D000818:Animals; D005260:Female; D005455:Fluorescent Antibody Technique; D006023:Glycoproteins / Q000032:analysis; D000882:Haplorhini; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D008252:Macaca fascicularis; D008253:Macaca mulatta; D008970:Molecular Weight; D009928:Organ Specificity; D002679:Pan troglodytes; D010215:Papio; D010920:Placenta / Q000032:analysis / Q000201:enzymology; D010928:Placental Lactogen / Q000032:analysis; D011247:Pregnancy; D011323:Primates
D006023:Glycoproteins; D010928:Placental Lactogen; D000469:Alkaline Phosphatase
Eine vergleichende Untersuchung von plazentaspeczifischen Proteinen bei Mensch und subhumanen Primaten