Glucidic and lipidic metabolic changes in rats induced by irradiation and the effect of adrenalectomy.
In experiments on X-irradiated rats (1000 R) the hepatic glycogen, total lipids, phospholipids content, and plasma glucose, cholesterol and beta-lipoprotein concentration were determined in intact and adrenalectomized animals. It was confirmed that irradiation produces a hepatic glycogen and blood glucose increased concentration. The glucidic metabolic response on irradiation is diminished by adrenalectomy. The adrenalectomy-induced modifications in the lipid metabolism of irradiated rats are more inconstant, which corresponds with its relative independence from glucocorticoid hormones.
D000302:Adrenal Cortex / Q000502:physiology; D000315:Adrenalectomy; D000818:Animals; D050260:Carbohydrate Metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism*; D008297:Male; D011830:Radiation Effects; D051381:Rats