Intravenous infusion bottle plugs as a source of microbial contamination.
A technique was described for the artificial contamination of the upper surface of intravenous infusion container plugs with viable micro-organisms. This technique was employed to assess the adequacy of decontamination of two designs of plug by the use of antiseptic swabbing. Results indicated that the MRC plug surface was more difficult to sterilize than that of the Travenol plug. The possibility of contamination of the infusion fluid during insertion of the giving-set needle was examined. Results indicated that there was a risk of contamination through the administration-set port of the MRC plug if swabbing was inadequate.
D001410:Bacillus megaterium / Q000302:isolation & purification*; D004340:Drug Contamination; D004349:Drug Packaging; D007263:Infusions, Parenteral; D013210:Staphylococcus / Q000302:isolation & purification*; D013242:Sterilization