Pathogenesis of aleutian disease of mink: identification of nonpersistent infections.
Aleutian disease virus usually produces a persistent infection and progressive immune comples disease in mink of the Aleutian genotype. Study of Aleutian disease virus infection in non-Aleutian mink showed that about one-quarter developed nonpersistent infections by the virus, and that the nonpersistence was not genetically determined by the host. The nonpersistently infected mink developed only a transient elevation of serum gamma globulin, and much lower specific Aleutian disease virus antibody titers than persistently infected mink. No lesions were found in the nonpersistently infected mink.
D000453:Aleutian Mink Disease / Q000209:etiology* / Q000276:immunology; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000917:Antibody Formation; D001797:Blood Protein Electrophoresis; D005260:Female; D005455:Fluorescent Antibody Technique; D008099:Liver / Q000382:microbiology; D008431:Maternal-Fetal Exchange; D008907:Mink; D011247:Pregnancy; D014713:Viruses, Unclassified / Q000276:immunology*
D000914:Antibodies, Viral