[Localization of dioctyl-phthalate on normal immunoglobulins G and on those of Kahler's disease (author's transl)].
After having identified as dioctyl-phthalate (DOP), a plasticizer that comes out with fatty acids of normal immunoglobulins G (IgG) and of those of Kahler's disease, we found out that DOP is preferentially bound to the heavy chains of IgG and is either missing from myeloma proteins or more abundant in them than in normal ones.
D002852:Chromatography, Ion Exchange; D004051:Diethylhexyl Phthalate / Q000032:analysis*; D006801:Humans; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000032:analysis; D007143:Immunoglobulin Heavy Chains / Q000032:analysis; D009101:Multiple Myeloma / Q000097:blood*; D010795:Phthalic Acids / Q000032:analysis*
D007074:Immunoglobulin G; D007143:Immunoglobulin Heavy Chains; D010795:Phthalic Acids; D004051:Diethylhexyl Phthalate
Localisation de dioctyl-phtalate sur les immunoglobulines G normales et sur celles de la maladie de Kahler