title: [Immunochemical studies on aldolase isoenzymes in human serum (author's transl)].
abstract: Analysis of human serum aldolase isoenzymes A, B and C activities was performed by means of a recently developed immunochemical assay. Isoenzyme patterns were established in 130 healthy subjects selected from a normal range research program. Total aldolase activity ranged from 0.8, 1.6,  2.5 U/L, Ald A from 0.6, 1.2, 1.9 U/L, Ald B 0.0, 0.2, 0.7 U/L, Ald C 0.0, 0.1, 0.4 U/L expressed as chi plus or minus 2 s range. Comparing the histograms of total aldolase activity in patients with acute hepatitis and normal controls, an almost identical frequency distribution in both groups was observed. However, histograms of aldolase isoenzyme B values of these groups were practically completely separated. Thus in contrast with total aldolase activity, the determination of aldolase isoenzyme B activity is a useful criterion in the diagnosis of acute hepatitis.
mesh_terms: D000906:Antibodies; D005634:Fructose-Bisphosphate Aldolase / Q000097:blood* / Q000276:immunology; D005985:Glyceraldehyde; D006509:Hepatitis B / Q000201:enzymology*; D006801:Humans; D005779:Immunodiffusion; D007527:Isoenzymes / Q000097:blood* / Q000276:immunology; D010756:Phosphoric Acids; D010783:Photometry; D011233:Precipitin Tests
chemical_list: D000906:Antibodies; D007527:Isoenzymes; D010756:Phosphoric Acids; D005985:Glyceraldehyde; D005634:Fructose-Bisphosphate Aldolase
vernacular_title: Aktivitätsbestimmung der Isoenzyme der Aldolase im menschlichen Serum mit Hilfe päzipitierender Antikörper