Determination of the primary structure of a mouse IgG2a immunoglobulin. Amino-acid sequence of the light chain.
The amino acid sequence of the light chain of the mouse monoclonal MOPC 173 immunoglobulin molecule (IgG2a,chi) is presented. This kappa chain contains 214 residues. Comparisons of this sequence with murine kappa chains already published by other workers bring a confirmation of the large size of the murine V chi chain pool. A complete identity was found with the constant region of the light chain of MOPC 21 from residue 97 to residue 214.
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D002460:Cell Line; D002918:Chymotrypsin; D003488:Cyanogen Bromide; D007074:Immunoglobulin G / Q000032:analysis*; D007147:Immunoglobulin Light Chains / Q000032:analysis*; D007145:Immunoglobulin kappa-Chains / Q000032:analysis*; D009194:Myeloma Proteins / Q000032:analysis*; D010434:Pepsin A; D010446:Peptide Fragments / Q000032:analysis; D014357:Trypsin
D000596:Amino Acids; D007074:Immunoglobulin G; D007147:Immunoglobulin Light Chains; D007145:Immunoglobulin kappa-Chains; D009194:Myeloma Proteins; D010446:Peptide Fragments; D002918:Chymotrypsin; D014357:Trypsin; D010434:Pepsin A; D003488:Cyanogen Bromide