Effect of haemin on endogenous protein synthesis in oocytes of the Queensland cane toad Bufo marinus.
Although general protein synthesis as measured by L-[3H]leucine incorporation is unaffected by injection of haemin into oocytes of B. marinus, the synthesis of at least two proteins is repressed. It appears that haemin is capable of exerting inhibitory effects on eukaryote protein synthesis as well as stimulating it as previously reported by other workers.
D000818:Animals; D002024:Bufo marinus; D003864:Depression, Chemical; D005260:Female; D006418:Heme / Q000031:analogs & derivatives*; D006427:Hemin / Q000494:pharmacology*; D007930:Leucine / Q000378:metabolism; D009865:Oocytes / Q000378:metabolism*; D010063:Ovum / Q000378:metabolism*; D010649:Phenylalanine / Q000378:metabolism; D014176:Protein Biosynthesis; D014633:Valine / Q000378:metabolism
D006418:Heme; D010649:Phenylalanine; D006427:Hemin; D007930:Leucine; D014633:Valine