Evaluation of HBsAg detection methods from AABB-CAP survey data.
The results obtained by referees and participants on nine HBsAg survey panels are reviewed. Comparison of the two methods used by the majority of participants, counterelectrophoresis (CEP) and radioimmunoassay (RIA), shows that the latter consistently identifies a larger number of the positive samples. The RIA results show some problems with specificity, but these were reduced during the two-year period. The performance of the participants using CEP improved during the two-year period. The Survey documents the change in popularity of the methods.
D001771:Blood Banks; D004586:Electrophoresis; D005189:False Positive Reactions; D006386:Hemagglutination Tests; D006511:Hepatitis B Antigens / Q000032:analysis*; D006801:Humans; D005779:Immunodiffusion; D007158:Immunologic Techniques / Q000379:methods*; D007753:Laboratories / Q000592:standards; D007841:Latex Fixation Tests; D010336:Pathology; D011786:Quality Control; D011863:Radioimmunoassay; D012955:Societies, Medical; D014481:United States
D006511:Hepatitis B Antigens