title: Immune response to a purified cytoplasmic protein of Neisseria gonorrhoeae.
abstract: This paper describes studies based on the hypothesis that the immunogenicity of the gonococcus is impaired by a component toxic to immunocytes. Cytoplasm of colony type 1 gonococci was found to contain a protein fraction beta+t not present in colony type 4 gonococci. From the results of further analysis it is tentatively deduced that beta+t consists of a toxic component Tbeta-t and an immunogen.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D000942:Antigens, Bacterial / Q000302:isolation & purification; D001426:Bacterial Proteins / Q000276:immunology* / Q000302:isolation & purification; D003315:Cornea / Q000276:immunology; D003593:Cytoplasm / Q000276:immunology; D007109:Immunity; D009344:Neisseria gonorrhoeae / Q000276:immunology*; D011817:Rabbits
chemical_list: D000596:Amino Acids; D000942:Antigens, Bacterial; D001426:Bacterial Proteins