[Pulmoscintigraphic long-term observations during postoperative irradiation of the mammary region (author's transl)].
The effect of ionizing rays on the pulmonary tissue during postoperative high-voltage therapy of breast cancer was investigated by a long-term study with the help of X-rays and nuclear techniques. The results prove that--in spite of optimal irradiation techniques--a local reduction of the pulmonary perfusion takes place as well as a shift of the cardiac output into other pulmonary areas, which are not exposed to the irradiation. Hereby, the pulmonary global function shows no significant change, as other authors have already pointed out. Likewise, no alteration was seen of the simple X-ray film after the use of this irradiation technique. In the pulmonary scintigram, however, a local reduction of the pulmonary perfusion was already seen after the application of 1500 rd, which increased still more in the posttherapeutic period. There were no signs of relapses within the observation period of more than 17 months.
D001943:Breast Neoplasms / Q000175:diagnosis / Q000532:radiotherapy*; D002302:Cardiac Output / Q000528:radiation effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008168:Lung / Q000528:radiation effects*; D011652:Pulmonary Circulation / Q000528:radiation effects; D011877:Radionuclide Imaging; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D013997:Time Factors
Lungenszintigraphische Langzeitbeobachtungen bei postoperativer Bestrahlung der Mammaregion