[Effect of radiomimetics on the composition of proteins in the serum of dog].
In this paper the protein serum of dogs was investigated after an application of the radiomimetics of beta, beta'-dichlorodiethyl sulphide by means of immunoelectrophoresis. The applied dose of beta, beta'-dichlorodiethyl sulphide is 35 mg of live weight s.c. per dog. It was found that together with the lengthened time after the application the precipitation lines in the sphere of beta1- and alpha2-globulins increased. The disintegration and distance of the precipitation lines in the direction of the electrophoretic migration and immunodiffusion. In our case SE and IE in agar provide only a rough semi-quantitative picture of the different protein fractions of dog serum and of their changes after an application of radiomimetics.
D000818:Animals; D000917:Antibody Formation; D001798:Blood Proteins / Q000276:immunology*; D011232:Chemical Precipitation; D004285:Dogs; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007136:Immunoglobulins / Q000302:isolation & purification; D051379:Mice; D009153:Mutagens / Q000494:pharmacology*; D051381:Rats; D013440:Sulfides / Q000494:pharmacology
D001798:Blood Proteins; D007136:Immunoglobulins; D009153:Mutagens; D013440:Sulfides
Vliv radiomimetik na slození bĩlkovin krevnĩho sera psŭ