Presence of D and I forms of glycogen synthase in adult frog liver.
Liver glycogen synthase from adult non-treated frogs is essentially completely dependent on glucose-6-P. Administration of glucose to the animals promotes the appearance of a form of glycogen synthase in absence of glucose-6-P. These two forms show different kinetic characteristics. The enzyme from glucose injected animals corresponds to an I form whereas the enzyme from non-treated animals appears to be a D form.
D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D001001:Anura; D005260:Female; D006006:Glycogen Synthase / Q000378:metabolism*; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D010710:Phosphates / Q000494:pharmacology; D011898:Ranidae; D013431:Sulfates / Q000494:pharmacology
D010710:Phosphates; D013431:Sulfates; D000255:Adenosine Triphosphate; D006006:Glycogen Synthase