title: The effect of tolazoline on right-to-left shunting via a patent ductus arteriosus in meconium aspiration syndrome.
abstract: Since arterial blood oxygen tensions are used in the evaluation of treatment of patients with meconium aspiration syndrome, it is important to recognize the occurrence of significant right-to-left shunting via a patent ductus arteriosus. The clinical findings, evidence of right-to-left ductus shunting, and outcome in eight patients with meconium aspiration syndrome are presented. Administration of tolazoline HCl and curare produced a beneficial effect on their PaO2 values.
mesh_terms: D004374:Ductus Arteriosus, Patent / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D008471:Meconium Aspiration Syndrome / Q000175:diagnosis / Q000209:etiology*; D014043:Tolazoline / Q000627:therapeutic use*
chemical_list: D014043:Tolazoline