title: The circular dichroic spectra of several sialic acid-containing polysaccharides isolated from Neisseria meningitidis.
abstract: The circular dichroic spectra of the acid and sodium salt forms of several sialic acid-containing homo- and hetero-polysaccharides have been measured. The spectra are shown to be influenced by the state of ionization of the carboxyl groups contained in the sialic acid, the location within the individual sialic acid residues of the inter-saccharide linkages, and changes in the configuration of hydroxyl groups remote to the carboxyl group of the sialic acid.
mesh_terms: D002942:Circular Dichroism; D008968:Molecular Conformation; D009345:Neisseria meningitidis / Q000032:analysis*; D011135:Polysaccharides, Bacterial / Q000302:isolation & purification; D012794:Sialic Acids / Q000032:analysis; D013056:Spectrophotometry, Ultraviolet
chemical_list: D011135:Polysaccharides, Bacterial; D012794:Sialic Acids