title: Altered adaptation behavior in the elderly (author's transl).
abstract: Adaptation processes in an acute stress situation were investigated an compared in young and elderly subjects. Insulin hypoglycemia was used to provoke stress. The behavior of the blood sugar after administration of 0.1 U/kg old insulin shows a marked hypoglycemic state after 30 minutes, both in the young and in the older subjects. The rise into the normal range occurs considerably quicker in the young than in the elderly. Adrenaline excretion is distinctly lowered in older people. Measurement of hydrocortisone excretion also shows a lower reaction level and a delayed onset in the elderly. Growth hormone analysis shows a smaller production in advanced age. It is consequently established that adaptation potential decreases in old age.
mesh_terms: D000222:Adaptation, Physiological; D000328:Adult; D000368:Aged; D000375:Aging; D004837:Epinephrine / Q000378:metabolism; D005790:General Adaptation Syndrome / Q000503:physiopathology*; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D007003:Hypoglycemia / Q000139:chemically induced / Q000503:physiopathology; D007328:Insulin; D013312:Stress, Physiological / Q000139:chemically induced / Q000503:physiopathology*
chemical_list: D007328:Insulin; D013006:Growth Hormone; D006854:Hydrocortisone; D004837:Epinephrine
vernacular_title: Verändertes adaptationsverhalten im höheren Alter