title: [Effect of levomycetin on the microflora artificially introduced into the intestines of gnotobiotic chicks].
abstract: Levomycetin effect on the microflora introduced into the intestine of abiotic chickens was studied. Levomycetin in a dose of 4 mg perosone chicken for 5 days provided a decrease in the number of Bifidobacteria, Lactobacteria, Escherichia and Enterococci by 100 to 10000 times and an increase in the number of Candida or disbacteriosis in the intestine. The highest effect was observed with respect to multiplication of Lactobacteria. This impaired the ecological quantitative ratio between the microorganisms. Re-establishment of the microbial biocenosis after discontinuation of levomycetin use was not complete. Repeated disbacteriosis in the gastrointestinal tract of the test-chickens was registered on the 16th day.
mesh_terms: D000191:Actinomycetaceae / Q000187:drug effects; D000818:Animals; D002176:Candida albicans / Q000187:drug effects; D002645:Chickens / Q000382:microbiology*; D002701:Chloramphenicol / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D013293:Enterococcus faecalis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D005856:Germ-Free Life / Q000187:drug effects*; D007422:Intestines / Q000187:drug effects / Q000382:microbiology*; D007778:Lactobacillus / Q000187:drug effects; D013997:Time Factors
chemical_list: D002701:Chloramphenicol
vernacular_title: Vliianie levomitsetina na mikrofloru, iskusstvenno vvedennuiu v kishechnik gnotobiotichnykh tsypliat