title: [Investigations of changes in the phenolsulphonphthalein plasma levels in pregnant women with EPH syndrome (author's transl)].
abstract: In 53 patients, 24 healthy pregnant women and 29 patients with EPH (edema, proteinuria, hypertension) syndrome, the intravenous phenolsulphonphthalein test was performed between the 32nd and 42 weeks of pregnancy. At the same time, the serum creatinine and estrogen excretion in the 24 hour urine were determined. According to this, normal pregnancy and also pregnancies with one or more symptoms of the EPH syndrome without raised blood pressure do not cause changes of the PSP plasma level. A statistically significant rise in the PSP plasma level is only found with a blood pressure of 140/90 mm Hg, and simultaneously a close correlation to the estrogen excretion in the urine (r = -0.4) and the blood pressure (r = 0.6). Estrogen excretion is reduced with increasing blood pressure (r = -0.75). No correlation could be established between the PSP serum level and the creatinine in the serum.
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D003404:Creatinine / Q000097:blood; D004967:Estrogens / Q000652:urine; D005260:Female; D006801:Humans; D007677:Kidney Function Tests; D010635:Phenolphthaleins / Q000097:blood*; D010637:Phenolsulfonphthalein / Q000097:blood*; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third
chemical_list: D004967:Estrogens; D010635:Phenolphthaleins; D003404:Creatinine; D010637:Phenolsulfonphthalein
vernacular_title: Untersuchungen über Veränderungen des Phenolsulfonphthalein-Plasmaspiegels bei Graviden mit EPH-Syndrom