title: Trial of sustained-release tetracycline in the treatment of gonorrhoea.
abstract: A trial of Sustamycin, a sustained-release preparation of tetracycline hydrochloride, in uncomplicated gonorrhoea in sixty males is described, Each patient was given an initial dose of 500 mg. followed by 250 mg. twice daily for 5 days. Of the 57 patients who attended for follow-up 47 (82-5 per cent.) were cured. There were no adverse reactions.
mesh_terms: D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D003692:Delayed-Action Preparations; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009344:Neisseria gonorrhoeae / Q000187:drug effects; D010406:Penicillins / Q000494:pharmacology; D013307:Streptomycin / Q000494:pharmacology; D013752:Tetracycline / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D003692:Delayed-Action Preparations; D010406:Penicillins; D013752:Tetracycline; D013307:Streptomycin