[Development of spleenic infection in the mouse following intravenous inoculation of various species of Brucella in smooth (S) or rough (R) phases].
The bacterial population in the spleen of mice inoculated intravenously by Brucella abortus 544 (S), Brucella suis 1330 (S), Brucella melitensis 115 (R) or Brucella canis RM 666(R) is studied kinetically. Like the S strains of Brucella, the R strains are able to multiply in the mouse spleen. The consequences for the tests of vaccines against natural infections produced by S or R strains of Brucella are discussed.
D000818:Animals; D002002:Brucella / Q000472:pathogenicity*; D002003:Brucella abortus / Q000472:pathogenicity; D002006:Brucellosis / Q000503:physiopathology*; D002452:Cell Count; D002473:Cell Wall; D005260:Female; D051379:Mice; D013154:Spleen / Q000382:microbiology; D013158:Splenic Diseases / Q000503:physiopathology*; D013997:Time Factors
Evolution de l'infection splénique de la souris après inoculation intraveineuse de diverses espèces de Brucella en phase lisse (S) ou rugueuse (R)