[Effect of catecholamines on the metabolism of glucose, fatty acids and on the heart rate in goats].
In goats of the Bohemian white breed the effects of increasing doses of adrenaline and noradrenaline on the changes of glycemia, the NEFA level in the plasma, and on changes of the cardiac frequency were investigated. The reaction of the cardiac frequency to i. v. applications of adrenaline and noradrenaline corresponded, as a matter of fact to the reaction observed in monogastric animals. Between adrenaline doses of 6.25 and 12.5 mug kg(-1) no conclusive difference was recorded in the effect on an increase of glycemia. Only in the case of the application of adrenaline in a dose of 25.0 mu kg(-1) there occurred a conclusively higher response of glycemia compared with the lower doses. In the case of noradrenaline no dependence on concentration was recorded in the glycemic response. Between the applied dose of both catecholamines and the increased NEFA level no dependence on concentration was observed. No interaction between the acting of adrenaline and insulin was recorded. The results obtained indicate that adrenaline and insulin affect the cardiac frequency and the level of glycemia independently from each other.
D000818:Animals; D001786:Blood Glucose; D002395:Catecholamines / Q000494:pharmacology*; D004734:Energy Metabolism / Q000187:drug effects; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D006041:Goats / Q000378:metabolism / Q000502:physiology*; D006339:Heart Rate / Q000187:drug effects*
D001786:Blood Glucose; D002395:Catecholamines; D005230:Fatty Acids, Nonesterified
Vliv katecholaminů na metabolismus glukózy, mastných kyselin a na srdecní frekvenci u koz