[Autographical investigations of the transfer of labeled RNA from macrophages to lymphocytes (author's transl)].
By means of electron microscopic autoradiography we demonstrated a radioactivity in mice spleen lymphocytes after a common cultivation for 1 h with 3H-uridine marked autologian macrophages, washed profoundly. The radioactivity in lymphocytes is small after contact with unstimulated macrophages and is markedly increased after common cultivation with antigen stimulated macrophages. A transfer of RNA molecules of macrophages into lymphocytes is supposed.
D000818:Animals; D000917:Antibody Formation; D001345:Autoradiography; D001692:Biological Transport; D004731:Endotoxins / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology* / Q000648:ultrastructure; D008264:Macrophages / Q000276:immunology* / Q000648:ultrastructure; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D008854:Microscopy, Electron; D012313:RNA / Q000276:immunology* / Q000378:metabolism
D004731:Endotoxins; D012313:RNA
Autoradiographische Untersuchungen zur Frage des Transfers markierter RNS von Makrophagen auf Lymphocyten