[Correlation between serum values of copper, ceruloplasmin, SMAO, SDAO, in health- subjects, in pregnant women and in some pathological conditions (author's transl)].
Copper directly reactive with diethylditiocarbamate, ceruloplasmin, monoamine oxidase (SMAO) and diamine oxidase of the serum (SDAO) were studied in healthy subjects, in nine months pregnant women and in some pathological conditions. Increased values of copper were found in pregnancy. Ceruloplasminaemia was increased in hyperthyroidism, congestive hearth failure, Hodgkin's disease, and in pregnancy. Ceroluplasminaemia was strongly reduced in Wilson's disease. SMAO was increased during pregnancy. Statistical analysis showed no correlations between the variations of the data in different pathological conditions. In healthy subjects and in pregnant women, correlation was found between the values of ceruloplasmin obtained using both enzymatic and KCN methods. Statistical analysis of regression lines obtained in both groups of patients showed significative differences between slopes and elevations. It is possible that ceruloplasmin in pregnant women has different composition compared with healthy controls.
D000293:Adolescent; D000328:Adult; D000368:Aged; D006631:Amine Oxidase (Copper-Containing) / Q000097:blood*; D002570:Ceruloplasmin / Q000032:analysis*; D003300:Copper / Q000097:blood*; D005260:Female; D006333:Heart Failure / Q000097:blood; D006527:Hepatolenticular Degeneration / Q000097:blood; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood; D008103:Liver Cirrhosis / Q000097:blood; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000097:blood*; D009369:Neoplasms / Q000097:blood; D011247:Pregnancy
D003300:Copper; D002570:Ceruloplasmin; D006631:Amine Oxidase (Copper-Containing); D008995:Monoamine Oxidase
Relazione tra tassi sierici del rame, della ceruloplasmina, della monoaminossidasi e della diaminossidasi in condizioni normali, in gravidanza ed in alcuni stati morbosi