title: The pathogenicity of rough strains of Pseudomonas aeruginosa for Galleria mellonella.
abstract: Rough mutants of two strains of Pseudomonas aeruginosa have been isolated by selection for resistance to virulent lipopolysaccharide-specific phages. The rough mutants fell into two classes on the basis of colonial morphology and agglutination by acriflavine and NaCl. The pigment and exoenzyme-synthesizing properties of these derivatives were identical with those of the parental cultures. The rough strains were 8- to 62-fold less pathogenic for the larvae of the wax moth (Galleria mellonella) than the smooth wild-type cells.
mesh_terms: D000818:Animals; D006460:Hemolysin Proteins / Q000096:biosynthesis; D007814:Larva / Q000382:microbiology; D008049:Lipase / Q000096:biosynthesis; D009036:Moths / Q000382:microbiology*; D009154:Mutation; D010447:Peptide Hydrolases / Q000096:biosynthesis; D010641:Phenotype; D010740:Phospholipases / Q000096:biosynthesis; D010860:Pigments, Biological / Q000096:biosynthesis; D011550:Pseudomonas aeruginosa / Q000166:cytology / Q000378:metabolism / Q000472:pathogenicity*; D014774:Virulence
chemical_list: D006460:Hemolysin Proteins; D010860:Pigments, Biological; D010740:Phospholipases; D008049:Lipase; D010447:Peptide Hydrolases