Mitochondrial metabolism in infarcting myocardium.
The isolation medium plays an important part in the assessment of mitochondrial damage following coronary artery ligation. Albumin added to either isolation or incubation medium can protect. A depression of oxygen uptake is found only after prolonged ischemia or in a simple incubation medium. Hence mitochondrial oxygen wastage probably occurs in the infarction process.
D000818:Animals; D003327:Coronary Disease / Q000378:metabolism; D004285:Dogs; D000882:Haplorhini; D008931:Mitochondria, Muscle / Q000378:metabolism*; D009203:Myocardial Infarction / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption; D010215:Papio; D013997:Time Factors