A micrococcin-resistant mutant of Bacillus subtilis: localization of resistance to the 50s subunit.
The 50S subunit is the site of action of the antibiotic micrococcin. In addition, B. subtilis strain mic-1, which is resistant to micrococcin, contains altered 50S subunits.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects*; D001665:Binding Sites; D003227:Conjugation, Genetic; D004352:Drug Resistance, Microbial; D009154:Mutation; D010455:Peptides / Q000494:pharmacology; D010649:Phenylalanine / Q000378:metabolism; D011108:Polymers; D014176:Protein Biosynthesis; D012270:Ribosomes / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D010455:Peptides; D011108:Polymers; D010649:Phenylalanine