[Specificity of anti-ApA antibodies].
Antibodies to ApA elicited in Rabbits by immunization with bovine serum albumin-ApA conjugate have been purified by affinity chromatography. These purified antibodies react with bovine serum albumin-AMP, 8 bromo AMP, ApA conjugates as shown by gel diffusion. The association constants for the binding of antibodies and several haptens were deduced from dialysis equilibrium. The number of bound hapten molecules per antibody binding site depends upon the nature of the hapten.
D000227:Adenine Nucleotides / Q000276:immunology*; D000241:Adenosine / Q000276:immunology; D000249:Adenosine Monophosphate / Q000276:immunology; D000818:Animals; D000906:Antibodies / Q000302:isolation & purification; D000918:Antibody Specificity; D000937:Antigen-Antibody Reactions; D002846:Chromatography, Affinity; D003429:Cross Reactions; D006241:Haptens; D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D007700:Kinetics; D011817:Rabbits / Q000276:immunology; D012710:Serum Albumin, Bovine; D013329:Structure-Activity Relationship; D013696:Temperature
D000227:Adenine Nucleotides; D000906:Antibodies; D006241:Haptens; D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D012710:Serum Albumin, Bovine; D000249:Adenosine Monophosphate; D000241:Adenosine
Spécificité des anticorps anti-ApA