[The effect of prostaglandins E1 and A2 on the proliferation and phagocytosis of mouse peritoneal macrophages in culture].
The action of prostaglandins E1 and A2 was studied on the proliferation and the phagocytosis of mouse peritoneal macrophages in culture. The proliferation was not stimulated by prostaglandins E1 and A2, but the phagocytosis was increased by prostaglandin A2 and decreased by prostaglandin E1. These actions could be correlated with the regulatory role of prostaglandins.
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis; D003864:Depression, Chemical; D008264:Macrophages / Q000187:drug effects* / Q000276:immunology; D051379:Mice; D010538:Peritonitis / Q000276:immunology; D010587:Phagocytosis / Q000187:drug effects*; D011454:Prostaglandins A / Q000037:antagonists & inhibitors / Q000276:immunology / Q000494:pharmacology*; D011458:Prostaglandins E / Q000037:antagonists & inhibitors / Q000276:immunology / Q000494:pharmacology*; D013268:Stimulation, Chemical; D013936:Thymidine / Q000378:metabolism
D011454:Prostaglandins A; D011458:Prostaglandins E; D004247:DNA; D013936:Thymidine
Influence des prostaglandines E1 et A2 sur la prolifération et la fonction phagocytaire du macrophage péritonéal de Souris en culture