[The effect of nitroglycerine medication on the arterial oxygen pressure in obstructive lung disease].
Nitroglycerine gains increasing interest because of its favourable hemodynamic effects in patients with left heart failure, especially in those with coronary heart disease. The drug-induced vasodilatation and lowering of pulmonary arterial pressure, is followed by a redistribution of lung perfusion which occasionally may be deletarious. It is shown that in patients with obstructive lung disease, a significant drop in arterial oxygen tension may be observed. This could be due to increased perfusion of the lung, without a concommitant augmentation of ventilation, which results in an increase of right to left-shunt.
D000328:Adult; D004341:Drug Evaluation; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000627:therapeutic use*; D010100:Oxygen / Q000097:blood*; D010313:Partial Pressure; D012129:Respiratory Function Tests
D005996:Nitroglycerin; D010100:Oxygen
Auswirkungen einer Nitroglyzerinmedikation auf die arterielle Sauerstoffspannung bei obstruktiver Ventilationsstörung