Genetic control of immunoglobulin production by individual cell lines.
Production of more than one class of heavy chain or one type of light chain by individual cell lines of human and murine origin is described. The genetic and cellular events which could account for the observed patterns of production are discussed.
D000818:Animals; D002460:Cell Line; D006801:Humans; D007111:Immunity, Cellular; D007125:Immunogenetics; D007074:Immunoglobulin G / Q000096:biosynthesis; D007075:Immunoglobulin M / Q000096:biosynthesis; D007145:Immunoglobulin kappa-Chains / Q000096:biosynthesis; D007148:Immunoglobulin mu-Chains / Q000096:biosynthesis; D007136:Immunoglobulins / Q000096:biosynthesis*; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D010954:Plasmacytoma / Q000276:immunology
D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007145:Immunoglobulin kappa-Chains; D007148:Immunoglobulin mu-Chains; D007136:Immunoglobulins