title: Antibacterial activity of nitropyrroles, nitrothiphenes, and aminothiophenes in vitro.
abstract: The antibacterial activities of nitropyrroles, nitrothiophenes, and aminothiophenes were studied. Replacement of the nitro group with an amino group enhanced the activity of the thiophene compounds.
mesh_terms: D000588:Amines / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D004754:Enterobacter / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D009574:Nitro Compounds / Q000494:pharmacology*; D011514:Proteus vulgaris / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D011758:Pyrroles / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship; D013876:Thiophenes / Q000494:pharmacology*
chemical_list: D000588:Amines; D009574:Nitro Compounds; D011758:Pyrroles; D013876:Thiophenes