Incomplete tricarboxylic acid cycle in a type I methylotroph, Methylococcus capsulatus.
Alpha-Ketoglutaratedehydrogenase was undetectable in extracts of Methylococcus capsulatus. Cells incorporated [1-14-C] acetate into only four protein amino acids (glutamate, proline, arginine, and leucine) and the C5, but not C1, of glutamate.
D000085:Acetates / Q000378:metabolism; D001120:Arginine / Q000096:biosynthesis; D002474:Cell-Free System; D002952:Citric Acid Cycle; D005971:Glutamates / Q000096:biosynthesis; D007655:Ketoglutarate Dehydrogenase Complex / Q000032:analysis; D007930:Leucine / Q000096:biosynthesis; D008055:Lipids / Q000096:biosynthesis; D008772:Methylococcaceae / Q000201:enzymology / Q000378:metabolism*; D011392:Proline / Q000096:biosynthesis
D000085:Acetates; D005971:Glutamates; D008055:Lipids; D001120:Arginine; D011392:Proline; D007655:Ketoglutarate Dehydrogenase Complex; D007930:Leucine