title: Electrocardiographic measurement of cardiac function. Are the amplitude changes of the S wave indicative of changes in the size of the heart?
abstract: Preliminary tests to determine whether there is an electromechanical link between the electrocardiogram and cardiac function have been done by means of echocardiography. Three different haemodynamic manipulations which alter cardiac function, viz. nitroglycerin, intravenous digoxin and exercise-induced angina, were used. The changes in the S-wave amplitude, in selected leads, appear to be directionally related to the changes in the left ventricular enddiastolic volume. It is thus suggested that the S-wave changes may be indicative of changes in cardiac function.
mesh_terms: D000787:Angina Pectoris / Q000503:physiopathology; D001794:Blood Pressure; D002306:Cardiac Volume; D004077:Digoxin / Q000494:pharmacology; D004452:Echocardiography; D004562:Electrocardiography; D006321:Heart / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000494:pharmacology; D005082:Physical Exertion
chemical_list: D004077:Digoxin; D005996:Nitroglycerin