[Mathematical model of the effect of inorganic phosphorus on the tetracycline biosynthesis process].
A special apparatus with continuous dosing of substrates to flasks was used for experiments on the effect of inorganic phosphorus concentrations on the growth process of Act. aureofaciens and tetracycline biosynthesis. The experimental data showed that the character of the orthophosphorus effect on the mycellium growth and antibiotic biosynthesis was different. The relations were described with macrokinetic equations of Mono and Andrus type.
D003470:Culture Media; D004305:Dose-Response Relationship, Drug; D007700:Kinetics; D008433:Mathematics; D008956:Models, Chemical; D010758:Phosphorus / Q000494:pharmacology*; D013304:Streptomyces aureofaciens / Q000187:drug effects / Q000254:growth & development; D013678:Technology, Pharmaceutical / Q000295:instrumentation; D013752:Tetracycline / Q000096:biosynthesis*
D003470:Culture Media; D010758:Phosphorus; D013752:Tetracycline
Matematicheskaia model' vliianiia neorganicheskogo fosfora na protsess biosinteza tetratsiklina