title: The College of American Pathologists comprehensive blood bank survey program, 1973.
abstract: The 1973 Comprehensive Blood Bank Survey Program of the College of American Pathologists was administered to 2,200 laboratories and blood banks throughout the United States. The results showed a considerable increase in the accuracy of the testing and in the performance of reagents. Accuracy of ABO testing was 99.3%; Rh testing, 99%; crossmatching was 98.9% correct. Antibody detection was correct 96.3% of the time, with the exception of a cold-reacting anti-P1 which was found by only 62% of the participants. About the same number of laboratories also did not find the antibody during the crossmatch procedure. A sample from a donor with a positive antiglobulin test created much confusion and was misinterpreted in a number of ways. Reagents were found to be performing well with the exception of two, one [anti-hr'(C)] which produced a significant number of false positives, and another (anti-Kell) which produced numerous false negatives. The results seem to indicate that the anti-hr'(C) from several manufacturers is at fault for this error, while the anti-Kell errors showed no predilection for manufacturers and may represent erroneous testing by the laboratories or a failure to employ adequate quality control.
mesh_terms: D000017:ABO Blood-Group System; D000906:Antibodies / Q000032:analysis; D000888:Antibodies, Anti-Idiotypic / Q000032:analysis; D000941:Antigens / Q000032:analysis; D001771:Blood Banks / Q000592:standards*; D001789:Blood Group Antigens; D001787:Blood Group Incompatibility / Q000175:diagnosis; D003080:Cold Temperature; D005189:False Positive Reactions; D006801:Humans; D007202:Indicators and Reagents; D010336:Pathology; D011786:Quality Control; D012204:Rh-Hr Blood-Group System; D012955:Societies, Medical; D014481:United States
chemical_list: D000017:ABO Blood-Group System; D000906:Antibodies; D000888:Antibodies, Anti-Idiotypic; D000941:Antigens; D001789:Blood Group Antigens; D007202:Indicators and Reagents; D012204:Rh-Hr Blood-Group System