title: Osler as a medical geneticist.
abstract: Osler's immediate successor as Regius Professor at Oxford was Archibald Garrod (1857-1936), the founder of biochemical genetics. Like Mendel's, Garrod's concepts and discoveries were late in gaining wide currency and had in effect ot be rediscovered by Beadle and Tatum and by the students of biochemical individuality in the 1950s and 1960s. I have attempted to show that Garrod's predecessor Regius also contributed to medical genetics--not to its theoretical roots, to be sure, but certainly in an important way to the nosology of genetic disease.
mesh_terms: D000293:Adolescent; D000474:Alkaptonuria / Q000235:genetics / Q000266:history; D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics / Q000266:history; D000799:Angioedema / Q000235:genetics / Q000266:history; D002648:Child; D003327:Coronary Disease / Q000235:genetics / Q000266:history; D005260:Female; D030342:Genetic Diseases, Inborn / Q000266:history; D005823:Genetics / Q000266:history*; D005826:Genetics, Medical; D006467:Hemophilia A / Q000235:genetics / Q000266:history; D006666:History of Medicine; D006801:Humans; D008297:Male; D008404:Massachusetts; D009085:Mucopolysaccharidosis IV / Q000235:genetics / Q000266:history; D011792:Quebec; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000235:genetics / Q000266:history