title: [Group specific antibodies in generalized forms of meningococcal infection].
abstract: Seroconversion was revealed in the indirect hemagglutination test with a stable erythrocytic diagnostic agent containing meningococcus antigen of serogroup A in 93.4% of patients with generalized forms of meningococcus infection. A study of the sera obtained at various periods of the disease from 168 patients showed that the antibodies increased sharply during the first days, reaching the maximum (1:2560--1:10240) on the 5th--10th day of the disease; then the titres decreased somewhat becoming stabilizaed at the same level up to recovery. In 75--92% of the persons of control group (patients with meningites of nonmeningococcal etiology, healthy persons and those suffering from gonorrhea) the antibody titre was not over 1:20--1:40; no dynamic increase in its level was noted. The diagnostic value of the reaction for differentiation of meningococcus etiology from other meningites is emphasized.
mesh_terms: D000293:Adolescent; D000907:Antibodies, Bacterial; D000917:Antibody Formation; D000918:Antibody Specificity; D000942:Antigens, Bacterial; D002648:Child; D002675:Child, Preschool; D006069:Gonorrhea / Q000175:diagnosis; D006386:Hemagglutination Tests; D006801:Humans; D007223:Infant; D008581:Meningitis / Q000175:diagnosis; D008585:Meningitis, Meningococcal / Q000175:diagnosis; D008589:Meningococcal Infections / Q000175:diagnosis* / Q000276:immunology; D009302:Nasopharyngeal Diseases / Q000175:diagnosis; D009343:Neisseria / Q000276:immunology; D009344:Neisseria gonorrhoeae / Q000276:immunology; D009345:Neisseria meningitidis / Q000276:immunology*; D013045:Species Specificity; D013997:Time Factors
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial
vernacular_title: Gruppospetsificheskie antitela pri generalizovannykh formakh meningokokkovoĭ infektsii