Characterization of iturin A in antibiotics from various strains of Bacillus subtilis.
Iturin A, an antifungal lipopeptide characterized by the presence of homologous liposoluble beta-aminoacids was found to be the active component to bacillomycin B, bacillomycin R and eumycin. Iturin A was identified by thin-layer chromatography, aminoacid analysis and by characterization of liposoluble aminoacids and peptides. Another two preparations: the antibiotic of Raubitschek and the bacillomycin of Landy et al. contain components of the same structural type but they are different from iturin A.
D000596:Amino Acids / Q000032:analysis; D000935:Antifungal Agents / Q000032:analysis* / Q000096:biosynthesis / Q000302:isolation & purification / Q000494:pharmacology; D001412:Bacillus subtilis / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D005658:Fungi / Q000187:drug effects; D006868:Hydrolysis; D010455:Peptides / Q000032:analysis; D010456:Peptides, Cyclic; D012995:Solubility
D000596:Amino Acids; D000935:Antifungal Agents; D010455:Peptides; D010456:Peptides, Cyclic; C013579:iturin A