Carbonic anhydrase isoenzymes in the erythrocytes of new-born premature and full-term infants.
A specific and quantitative immunological method for the determination of human erythrocyte carbonic anhydrase isoenzymes B and C has been used to determine these enzymes in erythrocytes of umbilical cord blood. The investigations have shown a content of both isoenzymes less than 1:10 of that in adults. Premature infants have significantly lower values than full-term infants. The influence of carbonic anhydrase in the respiratory distress syndrome is discussed. No conclusions are drawn. The content of carbonic anhydrase in erythrocytes has been suggested as a laboratory parameter of maturity. In our investigations it does not seem to be useful for the evaluation of muturity.
D001724:Birth Weight; D002256:Carbonic Anhydrases / Q000097:blood*; D004912:Erythrocytes / Q000201:enzymology*; D005312:Fetal Blood; D005865:Gestational Age; D006801:Humans; D007122:Immunoelectrophoresis; D007231:Infant, Newborn; D007234:Infant, Premature; D007527:Isoenzymes / Q000097:blood*; D012127:Respiratory Distress Syndrome, Newborn / Q000201:enzymology
D007527:Isoenzymes; D002256:Carbonic Anhydrases