A quantitative study of the distribution of IgG sub-classes in a group of normal human sera.
The radial immunodiffusion method of Mancini has been applied to quantitative study of IgG subclasses in a normal population. The method was assessed in terms of both reproducibility and antiserum consumption. The distribution of IgG subclasses in a group of normal individuals was studied, and compared with their incidence in a series of monoclonal proteins investigated by previous workers and particularly with other quantitative studies on groups of normal individual's sera.
D000818:Animals; D005260:Female; D000882:Haplorhini / Q000276:immunology; D006801:Humans; D007106:Immune Sera; D007115:Immunization Schedule; D005779:Immunodiffusion / Q000592:standards; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000145:classification*; D008297:Male; D008722:Methods; D009194:Myeloma Proteins; D012756:Sheep / Q000276:immunology
D007106:Immune Sera; D007074:Immunoglobulin G; D009194:Myeloma Proteins