title: Further investigations of intestinal hormonal polypeptides.
abstract: Attempts are described to identify additional polypeptides of hormonal nature in a concentrate of intestinal polypeptides shown previously to contain secretin, cholecystokinin-pancreozymin (CCK), motilin, gastric inhibitory polypeptide (GIP), vasoactive intestinal polypeptide (VIP), enteroglucagon and chymodenin. The probable amino acid sequence of a variant form of CCK is disclosed. The possibility of using characteristic fragments of polypeptides for the quantitation of the polypeptides themselves in crude preparations is briefly discussed.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002766:Cholecystokinin / Q000032:analysis; D002850:Chromatography, Gel; D005749:Gastric Inhibitory Polypeptide / Q000032:analysis; D005768:Gastrointestinal Hormones / Q000032:analysis* / Q000302:isolation & purification; D009037:Motilin / Q000032:analysis; D010446:Peptide Fragments / Q000032:analysis; D010455:Peptides / Q000032:analysis* / Q000302:isolation & purification; D012633:Secretin / Q000032:analysis; D014660:Vasoactive Intestinal Peptide / Q000032:analysis
chemical_list: D005768:Gastrointestinal Hormones; D010446:Peptide Fragments; D010455:Peptides; D012633:Secretin; D014660:Vasoactive Intestinal Peptide; D009037:Motilin; D005749:Gastric Inhibitory Polypeptide; D002766:Cholecystokinin