The transfusion of Rh-positive blood into Rh-negative women.
The incidence of occurrence of transfusion of Rh-positive blood into Rh-negative individuals is unknown at the present time. A survey was designed to ascertain this information for the 12 month period ending March 31, 1974. Replies were obtained from 2,286 transfusion facilities in the United States. A total of 203 patients were reported to have received Rh-incompatible transfusions during the interval studied. Of these, 44 were women 49 years of age or under. Slightly more than half the women who received Rh-positive blood were treated with Rho (D) immune globulin. Those who received an adequate dose did not develop antibodies when appropriately tested. Twenty-five per cent of those who received an inadequate dose of Rh-immune globulin developed antibodies. Forty-two per cent of those receiving no Rh-immune globulin prophylaxis were noted to have antibodies.
D000328:Adult; D000906:Antibodies; D001787:Blood Group Incompatibility / Q000453:epidemiology* / Q000517:prevention & control / Q000628:therapy; D001803:Blood Transfusion; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000627:therapeutic use; D008875:Middle Aged; D012204:Rh-Hr Blood-Group System; D014481:United States
D000906:Antibodies; D007136:Immunoglobulins; D012204:Rh-Hr Blood-Group System