title: [Clinical examination of the blood of wild boars (Sus scrofa L.) naturally infested with parasites following administration of anthelminthics].
abstract: With 24 head of wild boars (Sus scrofa L.) of both sexes of the age of one to two years, kept in a game preserve and naturally infected with parasites of the species Mestastrongylus pudendotectus, M. elongatus, Ascarops strongylina, Physocephalus sexalatus, Ascaris suum, Globocephalus urosubulatus, Oesophagostomum dentatum, Trichocephalus suis, Eimeria debliecki, and E. perminuta, three experiments were performed with feeds premedicated with anthelmintics: pyrantel tartrate + diethylcarbamazine tartrate (a dose of 25 + 50 mg kg-1 of live weight), Mebendazole 5 p. c. premix and Mebendazole 50 p. c. premix (doses of 10 mg kg-1 and 40 mg kg-1 of live weight) administered for three consecutive days. According to the results of the helminthological dissections the effectiveness of pyrantel tartrate + diethylcarbamazine tartrate reached from 58.1 to 100 p. c. compared with the different species of nematodes, Mebendazole 5 p.c. premix from 47.8 to 100 p. c., and Mebendazole 50 p. c. premix reached the effectiveness of 85.4  to 100 p.c with the mentioned therapeutic doses. The results obtained from a coprological investigation showed the effectiveness, in the case of pyrantel tartrate + diethylcarbamazine tartrate, of 99.2 and 70.65 p. c. on the sixth and fifteeenth day after application, in the case of Mebendazole 5 p. c. premix 94.4 and 79.41 p. c. on the tenth and twentieth day after application, and in the case of of Mebendazole 50 p. c. premix it amounted to 96.0 and 100 p. c. on the tenth and twentieth day after application. In 22 head of wild boars of the total number of examined animals the minimum, maximum, and average values of the number of erythrocytes, leucocytes, of the hemoglobin content, of the hematocrit, MCV, MCH, MCHC, of the white blood count, of the protein total, of the fractions of albumin, alpha-, beta-, and gamma-globulin, of the activity of SGOT and SGPT, and of the metabolism of calcium, phosphorus, and magnesium were determined. The investigation was performed in the shortest possible time after the killing of the animals. In the examined values no marked deviations in 48 hours were found after the application had finished compared with the values determined in non-treated animals.
mesh_terms: D000818:Animals; D001562:Benzimidazoles / Q000008:administration & dosage*; D002118:Calcium / Q000097:blood; D008274:Magnesium / Q000097:blood; D008463:Mebendazole / Q000008:administration & dosage* / Q000627:therapeutic use; D010272:Parasitic Diseases / Q000188:drug therapy / Q000201:enzymology; D010273:Parasitic Diseases, Animal; D010758:Phosphorus / Q000097:blood; D013552:Swine; D013553:Swine Diseases / Q000097:blood* / Q000188:drug therapy / Q000201:enzymology; D000637:Transaminases / Q000097:blood
chemical_list: D001562:Benzimidazoles; D010758:Phosphorus; D008463:Mebendazole; D000637:Transaminases; D008274:Magnesium; D002118:Calcium
vernacular_title: Klinické vysetrení drve cerné zvĕre (Sus scrofa l.) priprozenĕ invadované parazity po aplikaci anthelmintik