[Transfer to the leukocytes of neonates by means of the plasma of patients with tuberculosis and of healthy persons of the ability to depress migration under the influence of antigens of mycobacterium tuberculosis in vitro].
A study was made of the effect of the blood plasma of patients suffering from tuberculosis and of healthy individuals on the in vitro migration in the presence of old tuberculin and the BCG vaccine of the leukocytes of neonates sensitive and insensitive to these antigens. Plasma of tuberculosis patients and more rarely of healthy persons created favourable conditions for depression of migration with old tuberculin and the BCG vaccine of the neonatal leukocytes insensitive to it on autoplasma, i.e. realized the transfer of the cellulo-mediated reactivity. In some cases the neonatal leukocyte migration by tuberculin on autoplasma was absent on the plasma of patients with tuberculosis of the lungs. A conclusion was drawn that the blood plasma of neonates suffering from tuberculosis and of adult healthy individuals contained quantitatively and qualitatively different factors determining different sensitivity of their leukocytes to the Mycobacteria antigens.
D000942:Antigens, Bacterial; D001500:BCG Vaccine; D006801:Humans; D066298:In Vitro Techniques; D007231:Infant, Newborn; D007962:Leukocytes / Q000276:immunology*; D008263:Macrophage Migration-Inhibitory Factors / Q000097:blood; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D014373:Tuberculin / Q000276:immunology; D014376:Tuberculosis / Q000276:immunology*
D000942:Antigens, Bacterial; D001500:BCG Vaccine; D008263:Macrophage Migration-Inhibitory Factors; D014373:Tuberculin
Perenos leĭkotsitam novorozhdennykh plazmoĭ bol'nykh tuberkulezom i zdorovykh lits sposobnosti k podavleniiu migratsii pod vliianiem antigenov mikobakteriĭ tuberkuleza in vitro