title: Protein degradation to low-molecular compounds after death and during reanimation.
abstract: The process of protein degradation to amino acids and peptides in rabbits following death and during reanimation in terms of the effects of artificial postmortem cooling on that process has been studied. Protein degradation was judged by increase of low-molecular nitrogenous compounds in serum and in organs by increase in soluble radioactivity with time in animals the proteins of which had been marked in vivo with radioisotopes. It has been found that immediately after death resulting from acute anoxia the processes of protein degradation to amino acids as well as synthesis stops in liver, skeletal and cardiac muscles, spleen, brain and spinal cord. Similar phenomenon takes place in the case of deep hypothermy. During reanimation the process of protein degradation to low-molecular compounds in organs restores.
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D001842:Bone and Bones / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D003643:Death; D007035:Hypothermia; D000860:Hypoxia; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D010455:Peptides / Q000378:metabolism; D011180:Postmortem Changes; D011506:Proteins / Q000378:metabolism*; D011817:Rabbits; D012151:Resuscitation; D013116:Spinal Cord / Q000378:metabolism; D013154:Spleen / Q000378:metabolism
chemical_list: D000596:Amino Acids; D010455:Peptides; D011506:Proteins