[Thyroxine in the treatment of euthyroid goiter and the prevention of goiter recurrence].
Patients with non-toxic goitre, or patients after an operation of non-toxic goitre, were given 75 mug thyroxine daily. The level of TSH decreased significantly only for the non-toxic goitre group. The TSH-TRH-test showed a high percentage of abnormal results, even after several months of treatment. An index for free thyroxine increased a little, but significantly. The neck sizes decreased only in the post-operative group significantly. The final scans showed a high percentage of goitres. 75 mug thyroxine is too small a dosage in these patients and 100 to 150 mug daily seem to be indicated in the above mentioned states.
D006042:Goiter / Q000188:drug therapy* / Q000517:prevention & control / Q000601:surgery; D006801:Humans; D011182:Postoperative Care; D012008:Recurrence; D013268:Stimulation, Chemical; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology; D013974:Thyroxine / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*
D013973:Thyrotropin-Releasing Hormone; D013972:Thyrotropin; D013974:Thyroxine
Thyroxin in der Behandlung der euthyreoten Struma und der Prophylaxe des Strumarezidivs