Complement profile and anticomplementary potential in mixed cryoglobulinemia.
In six mixed cryoglobulinemias we have found the indications of a complement classic pathway activation and the fall of the total hemolytic activity (CH50): cryoprecipitate anticomplementary power was always proportional to the respective serum CH50 fall, while no correlation with its own immunoglobulin constitution was found.
D000818:Animals; D000936:Antigen-Antibody Complex; D003165:Complement System Proteins / Q000302:isolation & purification*; D003450:Cryoglobulins / Q000302:isolation & purification*; D006801:Humans; D007136:Immunoglobulins / Q000302:isolation & purification; D008875:Middle Aged; D010265:Paraproteinemias / Q000276:immunology*; D011817:Rabbits; D012756:Sheep; D012859:Sjogren's Syndrome / Q000276:immunology; D008258:Waldenstrom Macroglobulinemia / Q000276:immunology
D000936:Antigen-Antibody Complex; D003450:Cryoglobulins; D007136:Immunoglobulins; D003165:Complement System Proteins