Vitamin B12 absorption studies using radioactive vitamin B12: comparison of whole body retention and urinary excretion after flushing dose (Schilling's test).
Vitamin B-12 absorption of 12 healthy young male subjects was determined by using labelled vitamin B-12 by Schilling's test and whole body retention test. The whole body retention test was performed first using low energy Co57 isotope and a week later, Schilling's test was performed. Whole body retention showed a mean absorption of 56.5% while Schilling's test showed mean absorption of 16.9% in the same subjects. Data supports the whole body retention test being more accurate.
D000328:Adult; D003037:Cobalt Radioisotopes; D006801:Humans; D007408:Intestinal Absorption; D008297:Male; D008875:Middle Aged; D012546:Schilling Test; D014805:Vitamin B 12 / Q000378:metabolism* / Q000652:urine; D014915:Whole-Body Counting
D003037:Cobalt Radioisotopes; D014805:Vitamin B 12