Retreatment of drug-sensitive relapses of pulmonary tuberculosis following chemotherapy with standard drugs.
Forty-four tuberculous patients who relapsed with strains sensitive to the initial drugs they had received, namely streptomycin and isoniazid, were retreated with the same drugs for a year. One died of tuberculosis, and two had treatment changed for unfavourable response. All the other 41 showed a bacteriological response, and all but one were culture-negative at 1 year or when last assessed.
D010131:Aminosalicylic Acid / Q000627:therapeutic use; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D012008:Recurrence; D013307:Streptomycin / Q000627:therapeutic use; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D010131:Aminosalicylic Acid; D007538:Isoniazid; D013307:Streptomycin