title: [Advances in the treatment of duodenal ulcer. Shortened healing time under high Paspertin dosage (author's transl)].
abstract: Metoclopramide (Paspertin) was administered to 30 patients with duodenal ulcer at an average dosage of 2 tablets three times daily (= 60 mg/day). An immediate alleviation of pain was noted in all cases, and complete freedom from complaints has usually occurred after 3 to 8 days. Radiological examinations revealed a good relaxation of the terminal antrum, elimination of spasms in the pyloric region, quick emptying of the stomach and a normal relief of the duodenal mucosa. The excellent efficacy was noted particularly in chronic ulcers resistant to conventional medication.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D004381:Duodenal Ulcer / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D005750:Gastric Juice / Q000378:metabolism; D005769:Gastrointestinal Motility; D006801:Humans; D007413:Intestinal Mucosa / Q000503:physiopathology; D008297:Male; D008787:Metoclopramide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D011446:Prospective Studies; D011859:Radiography
chemical_list: D008787:Metoclopramide
vernacular_title: Fortschritte in der Therapie des Ulcus duodeni. Verkürzte Heildauer unter hohen Gaben von Paspertin