[Detection of the GS-antigen of D-type virus in the cells of human breast fibroadenoma].
Gs-antigen(s) of the D-type virus isolated from the continuous cells of human carcinoma was detected by the immunodiffusion with an indirect radioimmunoautographic assay in 5 of 7 human breast fibroadenoma. This virus contained gs-antigen common with the MPMV. These data demonstrated the genom of the D-type virus (or of a similar virus) to be integrated with the human fibroadenoma cells genom. Expression of the virus genom takes place at least to the level of the virus gs-antigen synthesis. The D-type virus from the continuous cell cultures of human carcinoma was associated with some human tumours, one of which was fibroadenoma.
D000232:Adenofibroma / Q000473:pathology*; D000956:Antigens, Viral / Q000302:isolation & purification*; D001345:Autoradiography; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D005779:Immunodiffusion; D009858:Oncogenic Viruses / Q000276:immunology*; D011863:Radioimmunoassay / Q000379:methods
D000956:Antigens, Viral
Obnaruzhenie GS-antigena virusa D-tipa  v kletkakh fibroadenom molochnykh zhelez cheloveka.