[Investigations on the utilization of parenterally administered amino acids in premature and small-for-dates neonates. IV. Control of the amino acid blood level during infusion of a pharmacokinetically balanced amino acid solution (author's transl)].
An amino acid solution composed according to pharmacokinetic criteria was infused in 12 premature and 4 full-term infants. Imbalances of amino acids were not observed when the upper limit of the fasting level was accepted as a measure for balance or imbalance. The net transfer of total amino acids increased by about 40% over that in former experiments (second communication (4)). A decrease of cystine, a semiessential amino acid, could be avoided. The results were compared with the literature. During infusion, the urinary excretion of amino acids was not increased showing nearly complete utilization of the infused amin acids.
D000596:Amino Acids / Q000008:administration & dosage* / Q000097:blood / Q000652:urine; D001724:Birth Weight; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000378:metabolism; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000378:metabolism; D010288:Parenteral Nutrition; D013997:Time Factors
D000596:Amino Acids
Untersuchungen über die Verwertung parenteral zugeführter Aminosäuren bei Frühgeborenen und hypotrophen Neugeborenen. IV. Blutspiegelkontrollen während der Infusion einer nach pharmakokinetischen Gesichtspunkten zusammengesetzten Aminosäurenlösung