Effects of naloxone and pentazocine on continuous shock-postponement responding by the pigeon.
The effects of pentazocine (3-30 mg/kg) and naloxone (3-100 mg/kg) were determined on the treadle-pressing behavior of pigeons under a schedule of shock postponement. Pentazocine increased the mean rate of responding at the 10 mg/kg dose, and greatly increased the mean shock rate at 30 mg/kg. Naloxone increased the mean response rate at all doses tested, without any increases in shock rates.
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D010856:Columbidae; D004305:Dose-Response Relationship, Drug; D008297:Male; D009270:Naloxone / Q000494:pharmacology*; D010423:Pentazocine / Q000494:pharmacology*
D009270:Naloxone; D010423:Pentazocine