Localized cervical lymphadenopathy induced by diphenylhydantoin sodium.
Diphenylhydantoin sodium is a standard drug in the treatment of convulsive disorders.  Numerous untoward reactions have been reported.  Lymphadenopathy related to drug-induced hypersensitivity has occurred.  A yound woman undergoing treatment for seizures developed a large, tender, localized neck mass, associated with trismus, spasmotic torticollis, fever, eosinophilia, and skin rash.  She was thought to be suffering from a deep cervical fascial space abscess.  Symptoms subsided rapidly after elimination of anticonvulsant medication.
D000328:Adult; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D004830:Epilepsy, Tonic-Clonic / Q000188:drug therapy; D005260:Female; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology / Q000648:ultrastructure; D008206:Lymphatic Diseases / Q000139:chemically induced* / Q000473:pathology; D010672:Phenytoin / Q000009:adverse effects* / Q000627:therapeutic use
D010672:Phenytoin