Demonstration of separate binding sites for the folate coenzymes and deoxynucleotides with inactivated Lactobacillus casei thymidylate synthetase.
D001665:Binding Sites; D003854:Deoxyribonucleotides / Q000378:metabolism*; D005033:Ethylmaleimide / Q000494:pharmacology; D005492:Folic Acid / Q000031:analogs & derivatives* / Q000378:metabolism; D007461:Iodoacetates / Q000494:pharmacology; D007700:Kinetics; D007780:Lacticaseibacillus casei / Q000201:enzymology*; D008780:Methyltransferases / Q000378:metabolism*; D011485:Protein Binding; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship; D013940:Thymidylate Synthase / Q000378:metabolism*
D003854:Deoxyribonucleotides; D007461:Iodoacetates; D005492:Folic Acid; D008780:Methyltransferases; D013940:Thymidylate Synthase; D005033:Ethylmaleimide