Correction of postoperative metabolic alkalosis and renal failure by hemodialysis.
Three postoperative patients with oliguirc renal failure and hypochloremic metabolic alkalosis were treated with hemodialysis using a specailly prepared high-chloride, low-acetate dialysate. This mode of therapy corrected the metabolic abnormalities and was significantly more effective than treatment with commercially available high-acetate dialysate at increasing the serum chloride and hydrogen ion concentration. Furthermore, hemodialysis with high-chloride, low-acetate dialysate corrected the clinical sequelae of hypoventilation, cardiac arrhythmia, and neuromuscular irritability associated with metabolic alkalosis while treating uremia simultaneously.
D058186:Acute Kidney Injury / Q000150:complications / Q000628:therapy*; D000471:Alkalosis / Q000150:complications / Q000628:therapy*; D006801:Humans; D011183:Postoperative Complications / Q000628:therapy*; D006435:Renal Dialysis; D013396:Suction