title: Benign hereditary nephritis.
abstract: The diagnosis, prognosis, and heredity of glomerulonephritis, in 207 members of one family over five generations was determined. No evidence of significant renal insufficiency or renal associated mortality was found. A history of urinary tract infections was obtained from 58 percent of those with hematuria. Several of those with nephritis also had high-frequency hearing losses. Two females with histories of urinary infections had elevated levels of serum creatinine. Many cases will probably be discovered if families are tested when a patient presents with benign recurrent hematuria with or without red blood cell casts. There may not be an obvious history of kidney disease or hematuria. Hereditary nephritis is not always a progressive renal disease.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media; D004342:Drug Hypersensitivity / Q000235:genetics; D005260:Female; D006311:Hearing Disorders / Q000235:genetics; D006417:Hematuria / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009394:Nephritis, Hereditary / Q000175:diagnosis / Q000235:genetics*; D010406:Penicillins
chemical_list: D003287:Contrast Media; D010406:Penicillins