[Effect of somatostatin on canine exocrine pancreas secretion stimulated by pancreozymin, secretin or test meal].
In 4 dogs with pancreatic and gastric fistulae the effect of somatostatin (SST) on the pancreas was investigated during stimulation by pancreozymin-secretin or by a test meal. The pancreozymin-secretin-induced enzyme output and bile flow, as well as the enzyme concentration and duodenal volume during test meal stimulation were significantly reduced by SST. SST caused a less marked decrease in bicarbonate concentration, while volume and bicarbonate output did not change.
D000818:Animals; D001639:Bicarbonates / Q000378:metabolism; D002766:Cholecystokinin / Q000378:metabolism; D004285:Dogs; D005747:Gastric Fistula / Q000378:metabolism; D010179:Pancreas / Q000187:drug effects* / Q000378:metabolism; D010185:Pancreatic Fistula / Q000378:metabolism; D012633:Secretin / Q000378:metabolism; D013004:Somatostatin / Q000494:pharmacology*
D001639:Bicarbonates; D012633:Secretin; D013004:Somatostatin; D002766:Cholecystokinin
Der Einfluss von Somatostatin auf die mittels Pankreozymin, Sekretin oder Testmahlzeit stimulierte exokrine Pankreassekretion beim Hund