title: Production of aflatoxicol from aflatoxin B1 by postmitochondrial liver fractions.
abstract: Fish liver postmitochondrial supernatant preparations in the presence of carbon monoxide were used to prepare purified aflatoxicol from aflatoxin B1 in high yield (23-38%). Such fish liver postmitochondrial and postmicrosomal supernatant preparations were five to ten times more active in making aflatoxicol than rat or human liver preparations under the same conditions.
mesh_terms: D000328:Adult; D000348:Aflatoxins / Q000378:metabolism*; D000818:Animals; D002248:Carbon Monoxide / Q000494:pharmacology; D005260:Female; D005399:Fishes / Q000378:metabolism; D006801:Humans; D008099:Liver / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged; D051381:Rats; D013045:Species Specificity; D013347:Subcellular Fractions / Q000187:drug effects / Q000378:metabolism*; D013997:Time Factors; D014337:Trout / Q000378:metabolism
chemical_list: D000348:Aflatoxins; D002248:Carbon Monoxide