Clindamycin and Carbenicillin in treatment of patients with intraabdominal and female genital tract infections.
Clindamycin alone and with an aminoglycoside or carbenicillin alone and with an aminoglycoside were used in therapy for 173 patients with intraabdominal or genital tract infections. Excellent or good results were obtained in 115 of 131 patients treated with clindamycin and 33 of 42 patients treated with carbenicillin. Few serious side effects were observed in patients who received either drug. The data indicate that clindamycin is an effective drug in these conditions and suggest that carbenicillin may be equally effective.
D000005:Abdomen; D000332:Aerobiosis; D000617:Aminoglycosides / Q000627:therapeutic use; D000693:Anaerobiosis; D001419:Bacteria / Q000302:isolation & purification; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D002228:Carbenicillin / Q000627:therapeutic use*; D002981:Clindamycin / Q000627:therapeutic use*; D004341:Drug Evaluation; D004361:Drug Tolerance; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D013045:Species Specificity
D000617:Aminoglycosides; D002981:Clindamycin; D002228:Carbenicillin