Protection against endotoxin-induced mortality in mice treated with transition metal salts.
Administration of manganese or chromium chloride 1 h before challenge with a single bolus of Salmonella typhosa endotoxin completely obviated death in endotoxin-challenged mice.
D000818:Animals; D002413:Cations, Divalent; D002857:Chromium / Q000494:pharmacology; D004731:Endotoxins / Q000633:toxicity*; D005260:Female; D008345:Manganese / Q000494:pharmacology*; D051379:Mice; D012485:Salmonella typhi / Q000276:immunology*
D002413:Cations, Divalent; D004731:Endotoxins; D002857:Chromium; D008345:Manganese