Examination of the potential mutagenicity of hair dye constituents using the micronucleus test.
12 compounds which are constituents of hair dyes or chemically related aromatic amines, aminophenols, their nitroderivatives and aromatic hydroxyderivatives were examined for evidence of mutagenic potential by means of the micronucleus test. None of the compounds tested caused an increase in the incidence of micronucleated erythrocytes after oral dosing.
D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects; D004396:Coloring Agents / Q000494:pharmacology*; D003358:Cosmetics / Q000494:pharmacology*; D004912:Erythrocytes / Q000187:drug effects*; D005260:Female; D006197:Hair; D006801:Humans; D008297:Male; D009153:Mutagens; D051381:Rats
D004396:Coloring Agents; D003358:Cosmetics; D009153:Mutagens