title: Experience with the EMIT method of determining anticonvulsant levels in serum.
abstract: Clinical and laboratory experience with the EMIT immunoassay method for the determination of serum phenobarbitone levels is reported. A modification of the published laboratory method permitting manual operation in a general clinical chemistry laboratory was used. In 42 of the 75 children monitored, the serum levels of phenobarbitone indicated a change of the prescribed dosage.
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D004827:Epilepsy / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D007118:Immunoassay; D010634:Phenobarbital / Q000097:blood* / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D010634:Phenobarbital