Formation of solid human mammary carcinoma in vitro.
An established line of human breast carcinoma, MCF-7, when cultured within the artificial capillary system, formed solid masses of tissue. Acinar and ductular patterns developed, having the ultrastructural appearance of breast tissue that responds to exogenous hormones.
D001943:Breast Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D002460:Cell Line; D003470:Culture Media; D046508:Culture Techniques / Q000379:methods*; D006801:Humans; D008567:Membranes, Artificial
D003470:Culture Media; D008567:Membranes, Artificial