[Contribution of cases to the new classification of polyposis syndrome in the gastrointestinal tract].
In Schweizerische Medizinische Wochenschrift 106, 894-897 (1976) an article was published on a kinship with hereditary "minor adenomatous polyposis" of the colon with a higher than expected incidence of carcinoma of the stomach. Evidence for a genetic relationship between this family (Sch.) and another branch with an isolated case (Sch. E.) of familial polyposis of the gastrointestinal tract was found. The patient Sch. E. is presented here. The polyposis of this patient is phenotypically identical with that found in the classical familial polyposis of the colon, but also exhibits features of "minor adenomatous polyposis". A systematic clinical-endoscopic examination of ten members of the patient's family produced no further cases of gastrointestinal polyposis of carcinomata. In the case of Sch. E., therefore, a spontaneous mutation is postulated. A new classification of the various types of colonic polyposis is suggested.
D000328:Adult; D003110:Colonic Neoplasms / Q000235:genetics / Q000601:surgery; D006801:Humans; D007417:Intestinal Polyps / Q000145:classification* / Q000235:genetics / Q000601:surgery; D008297:Male; D010375:Pedigree; D010641:Phenotype; D013274:Stomach Neoplasms / Q000145:classification* / Q000235:genetics
Ein kasuistischer Beitrag zu einer neuen Klassifikation der Polyposesyndrome im Magen-Darm-Trakt