title: A further example of Kp1/Ko exhibiting depression of some Kell group antigens.
abstract: This paper gives details of a family in which there are numerous examples of the heterozygous Kdegree state. The study was initiated by the presence of anti-Kpb in the serum of the propositus. Reactions with anti-K, anti-Ku, anti-Jsb and anti-K13 confirm that the Kdegree gene in trans with Kpa results in weaker expression of these Kell antigens. One example of anti-K showed some evidence of dosage effect with kKpb/Kdegree cells, but these results were not confirmed by quantitation studies.
mesh_terms: D001789:Blood Group Antigens; D004912:Erythrocytes / Q000276:immunology; D006579:Heterozygote; D007125:Immunogenetics; D007518:Isoantibodies / Q000032:analysis; D007626:Kell Blood-Group System; D010375:Pedigree
chemical_list: D001789:Blood Group Antigens; D007518:Isoantibodies; D007626:Kell Blood-Group System