Transient ischaemic attacks and increased platelet aggregability associated with oral contraceptives. Treatment with dipyridamole and aspirin.
A 24-year old woman after using birth control pills for two months began to suffer from frequent migraine-like attacks, which turned eventually into typical transient ischaemic attacks (TIAs). A significant increase in spontaneous platelet aggregation was found, and combined treatment with dipridamole and aspirin was started. After two months of treatment spontaneous platelet aggregation rate fell to normal limits and TIAs disappeared. A causal relationship between increased platelet aggregability and TIAs is supposed.
D000328:Adult; D001241:Aspirin / Q000627:therapeutic use*; D003276:Contraceptives, Oral / Q000009:adverse effects*; D004176:Dipyridamole / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000139:chemically induced* / Q000188:drug therapy; D010974:Platelet Aggregation / Q000187:drug effects*
D003276:Contraceptives, Oral; D004176:Dipyridamole; D001241:Aspirin