title: Endolymphatic sac surgery for hearing conservation in Meniere disease.
abstract: Thirty-five patients with Meniere disease underwent endolymphatic sac decompression and drainage with a Silastic sac-mastoid shunt. On the basis of patients' responses to a questionnaire and on analysis of preoperative and postoperative audiometric studies, we found the method to be an effective means for conservation or improvement of hearing and for relief of vertigo in patients with positive glycerol tests. Of the 35 patients, eight had negative glycerol tests and did not benefit from surgery (P less than .001). Of the 27 patients with positive glycerol tests, 70.4% (19) had no further vertigo, and 18,5% (5) had decreased frequency or severity of attacks (an overall relief of vertigo in 88.9%). Hearing was improved in 16 (59.2%) and stabilized in five (18.5%). Subjectively, 85.2% (23/35) of the patients were satisfied with the hearing results of their operation.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001299:Audiometry / Q000379:methods; D002648:Child; D003638:Deafness / Q000628:therapy*; D003664:Decompression; D004322:Drainage; D007758:Ear, Inner / Q000601:surgery*; D005069:Evaluation Studies as Topic; D005260:Female; D005990:Glycerol; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000601:surgery*; D008875:Middle Aged; D014012:Tinnitus / Q000628:therapy; D014717:Vertigo / Q000628:therapy
chemical_list: D005990:Glycerol