[Effect of bacterial polysaccharide on the quantity of rosette-forming cells in mice with decreased immunologic reactivity].
The influence of bacterial polysaccharide on the amount of the rosette-forming cells (RFC) in mice with decreased immunological reactivity (irradiation in a dose of 400 rad, gamma-rays, administration of cyclophosphamide in a dose of 200 mg/kg) was studied. Bacterial polysaccharide increased the amount of RFC in the intact, immunized and irradiated animals. However, polysaccharide produced no stimulating action on the RFC formation in mice treated with cyclophosphamide this confirming different nature of depression of the immunological reactivity under the effect of irradiation and cyclophosphamide.
D000818:Animals; D000937:Antigen-Antibody Reactions / Q000187:drug effects / Q000528:radiation effects; D000942:Antigens, Bacterial; D003520:Cyclophosphamide / Q000494:pharmacology; D007104:Immune Adherence Reaction; D007165:Immunosuppression Therapy; D051379:Mice; D008808:Mice, Inbred CBA; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D012485:Salmonella typhi / Q000276:immunology*; D013154:Spleen / Q000276:immunology*
D000942:Antigens, Bacterial; D011135:Polysaccharides, Bacterial; D003520:Cyclophosphamide
Vliianie bakterial'nogo polisakharida na kolichestvo rozetkoobrazuiushchikh kletok u mysheĭ so snizhennoĭ immunologicheskoĭ reaktivnost'iu