Efficacy of 5,6-dihydro-5-azathymidine against cutaneous herpes simplex virus in hairless mice.
5,6-Dihydro-5-azathymidine, administered subcutaneously, was active both prophylactically and therapeutically against cutaneous herpesvirus infection of hairless mice. Activity was comparable to that obtained with adenine arabinoside.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D006561:Herpes Simplex / Q000188:drug therapy*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D012874:Skin Diseases, Infectious / Q000188:drug therapy*; D013936:Thymidine / Q000031:analogs & derivatives* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D013936:Thymidine