Determination of papaverine in blood samples by gas-liquid chromatography and mass fragmentography.
The measurement of papaverine in blood samples by using either a glass capillary column with a flame-ionization detector or a packed column with mass fragmentographic detection is described. The two methods permit the determination of the normal range of concentrations of papaverine in blood (2-500 ng/ml). Owing to its high specificity, mass fragmentography is greatly superior to capillary chromatography, which is sometimes subject to interferences by solvent impurities.
D002849:Chromatography, Gas; D002853:Chromatography, Liquid; D008401:Gas Chromatography-Mass Spectrometry; D005898:Glass; D006358:Hot Temperature; D006801:Humans; D008722:Methods; D010208:Papaverine / Q000097:blood* / Q000652:urine; D012997:Solvents
D012997:Solvents; D010208:Papaverine