Hydrolytic enzymes in colorectal cancer.
Activities of sulphatases A/B, sulphatase C, beta glucuronidase, acid and alkaline phosphatase were measured in 38 cases of colorectal cancer. A wide variation in the levels of individual enzymes was observed, suggesting that certain patients might benefit from therapy with tailor made enzyme activated anti-tumour agent. The activity of sulphatase C was correlated with the other lour, but the enzyme profile could not predict the evofution of the disease.
D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D001192:Arylsulfatases / Q000378:metabolism; D003110:Colonic Neoplasms / Q000201:enzymology*; D005966:Glucuronidase / Q000378:metabolism; D006801:Humans; D006867:Hydrolases / Q000378:metabolism*; D012004:Rectal Neoplasms / Q000201:enzymology*
D006867:Hydrolases; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D001192:Arylsulfatases; D005966:Glucuronidase