[Mechanism of the effect of aspirin on the functional properties of thrombocytes].
As shown the inhibitory effect of aspirin administered in vivo on platelet aggregation and factor 3 release in vitro was due to the action of aspirin on the blood platelets and plasma cofactors: plasma from aspirinized rats dimished aggregability of platelets from untreated animals; plasma from untreated rats increased the aggregability and factor 3 availability of platelets from aspirinized animals.
D000818:Animals; D001241:Aspirin / Q000494:pharmacology*; D001792:Blood Platelets / Q000187:drug effects* / Q000378:metabolism; D003864:Depression, Chemical; D010974:Platelet Aggregation / Q000187:drug effects; D010977:Platelet Factor 3; D051381:Rats
D010977:Platelet Factor 3; D001241:Aspirin
O mekhanizme vozdeĭstviia aspirina na funktsional'nye svoĭstva trombotsitov