Ring 11 chromosome (46,xx,r11(p15q25)).
A girl has a stable chromosome 11, which does not reveal loss of any chromosomal material. She demonstrates small stature, mild retardation, behavior problems, mild abnormal EEG, prominent sole furrow, increased deep tendon reflexes and hypothyroidism; this latter condition may have contributed to her retardation.
D002648:Child; D002653:Child Behavior Disorders / Q000175:diagnosis / Q000235:genetics; D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D002906:Chromosomes, Human, 6-12 and X; D004569:Electroencephalography; D005260:Female; D006130:Growth Disorders / Q000175:diagnosis / Q000235:genetics; D006801:Humans; D007037:Hypothyroidism / Q000175:diagnosis / Q000235:genetics; D008607:Intellectual Disability / Q000175:diagnosis / Q000235:genetics; D007621:Karyotyping; D012018:Reflex