Effect of three ophthalmic solutions on chemical conjunctivitis in the neonate.
In an attempt to reduce chemical conjunctivitis after silver nitrate prophylaxis, three different ophthalmic solutions (sodium chloride, sterile water, and a boric acid-sodium borate solution) were used to irrigate the eyes immediately after prophylaxis in 450 neonates. Sterile water significantly reduced (P less than .02) the prevalence of chemical conjunctivitis when compared to the conventional sodium chloride rinse. A significantly greater prevalence of chemical irritation in low-birth-weight infants was also noted (P less than .02).
D001888:Boric Acids / Q000627:therapeutic use; D003231:Conjunctivitis / Q000139:chemically induced / Q000517:prevention & control*; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000517:prevention & control*; D009883:Ophthalmic Solutions; D012835:Silver Nitrate / Q000009:adverse effects*; D012965:Sodium Chloride / Q000627:therapeutic use; D014867:Water
D001888:Boric Acids; D009883:Ophthalmic Solutions; D014867:Water; D012965:Sodium Chloride; D012835:Silver Nitrate