[Effect of aminazine on elaboration and extinction of an instrumental alimentary reflex in puppies].
The role of the adrenoreactive structures of the stem reticular formation in the elaboration and extinction of a food-procuring reflex of lever pressing was studied in 40 to 50 days old puppies. A 0.05 mg/kg dose of chlorpromazine proved more effective than a 0.5 mg/kg dose, in reducing both the rate of formation and of extiction of the reflex. The change in the course of elaboration was connected with the appearance of the phenomenon of reinforcement anticipation, which is not inherent in normal puppies of an early age. It is assumed that a 0.05 mg/kg dose diminishes the adrenergic ascending influences which prevail in normal puppies of the given age, while a 0.5 mg/kg dose exerts not only an adreno- but a cholinolytic action as well, without changing the balance between the systems or influencing the behaviour of the puppies.
D000818:Animals; D002746:Chlorpromazine / Q000494:pharmacology*; D003216:Conditioning, Operant / Q000187:drug effects*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005108:Extinction, Psychological / Q000187:drug effects*; D005502:Food
D002746:Chlorpromazine
Vliianie aminazina na vyrabotku i ugashenie instrumental'nogo pishchevogo refleksa u shchenkov