Regulation of the cell cycle by diethylstilbestrol and progesterone in cultured endometrial cells.
Cultures of primary explanted rabbit endometrium epithelial cells were found to be a mixture of dividing or cycling (20%) and non-dividing or GO (80%) cells. The addition of diethylstilbestrol had the effect of switching most of the GO cells into the cell cycle and to shorten the length of the cell cycle through a shortening of G1 and S. Progesterone had the opposite effects.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004054:Diethylstilbestrol / Q000494:pharmacology*; D004717:Endometrium / Q000166:cytology*; D005260:Female; D011374:Progesterone / Q000494:pharmacology*; D011817:Rabbits
D011374:Progesterone; D004054:Diethylstilbestrol