Amyloidosis developing in experimental nocardia infections.
Swiss white and C57/BL/6J mice inoculated repeatedly with either Nocardia asteroides or Nocardia brasiliensis organisms developed amyloidosis over a 7-month period. Amyloidosis also developed in these mice within 6 weeks following a single large inoculum of either organism, but not in other in-bred mouse strains, suggesting a genetic influence in the pathogenesis of this form of secondary amyloidosis.
D000686:Amyloidosis / Q000209:etiology* / Q000235:genetics; D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D051379:Mice; D008815:Mice, Inbred Strains; D009617:Nocardia Infections / Q000150:complications* / Q000235:genetics