title: [Characteristics of tyrosine balance and oxidation in oligophrenia of different origin].
abstract: The author conducted a study of the tyrosine balance and the urine excretion of its metabolites: paraoxyphenylpyruvic and homogentistic acid in 39 oligophrenic patients of a nontypical and of 90 with an exogenous genesis. In exogenic forms of oligophrenia the oxidation of tyrosine was characterized by hypertyrosinemia, hypertyrosinuria, a drop of paraoxyphenylpyruvic acid excretion. In genotypical oligophrenia the most typical were high indices of tyrosinemia, tyrosinuria, excretion of paraphenylpyruvic acid and homogentistic acid.
mesh_terms: D000293:Adolescent; D001205:Ascorbic Acid / Q000652:urine; D002648:Child; D005260:Female; D006713:Homogentisic Acid / Q000652:urine; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics / Q000378:metabolism*; D008297:Male; D010667:Phenylpyruvic Acids / Q000652:urine; D013577:Syndrome; D014443:Tyrosine / Q000378:metabolism*
chemical_list: D010667:Phenylpyruvic Acids; D014443:Tyrosine; D006713:Homogentisic Acid; D001205:Ascorbic Acid
vernacular_title: Kharakteristika balansa i okisleniia tirozina pri oligofrenii razlichnogo proiskhozhdeniia