title: [Pathologo-anatomic and experimental study of the morphology of Q-fever].
abstract: The article presents a survey of the literature containing reports on lesions of some human organs in Q-fever and on a possible role of the pathogene--Rickettsia burnetii in the development of these lesions. Pathoanatomical findings were compared with those of the experimental investigations of the Q-rickettsial infectious process. The literature data and the author's own investigations confirm the capability of Rickettsia burnetii of parasitizing in cells of the reticulo-endothelial system. This is an important factor in the pathogenicity of this causative agent and lies at the root of the pathogenesis of Q-rickettsial infection.
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000473:pathology; D003381:Coxiella / Q000648:ultrastructure; D006351:Heart Valves / Q000473:pathology; D006644:Histiocytes / Q000382:microbiology; D006801:Humans; D008099:Liver / Q000473:pathology; D008168:Lung / Q000473:pathology; D051379:Mice; D012157:Mononuclear Phagocyte System / Q000473:pathology; D011778:Q Fever / Q000150:complications / Q000382:microbiology / Q000473:pathology*; D012214:Rheumatic Heart Disease / Q000150:complications
vernacular_title: Patologoanatomicheskoe i éksperimental'noe izuchenie morfologii Ku-rikketsioza