title: Dependence proneness, a key target for alcoholism research.
abstract: Many alcoholics appear to be especially susceptible to developing tolerance to and physical dependence on alcohol. Elucidation of a biochemical abnormality associated with this special proneness could lead to advances in both diagnosis and treatment of alcoholism.
mesh_terms: D000437:Alcoholism / Q000378:metabolism*; D004361:Drug Tolerance; D000431:Ethanol / Q000378:metabolism; D006801:Humans; D012106:Research; D019966:Substance-Related Disorders
chemical_list: D000431:Ethanol