Membrane structures of human oligodendroglioma.
Plasma membrane particles of four human oligodendrogliomas were distributed at random, and their average number per micronm2 plasma membrane was 1090+/-233 on face A and 230+/-46 on face B. Gap junction was occasionally visible, usually small in size and composed of a polygonal aggregate of several subunits: isodiametric particles, about 70-80 A in diameter, on face A and pits, about 30-40 A in diameter, on face B. Tight junction in two oligodendrogliomas was characterized by a meshwork of circular or ramifying crests on face A and complementary furrows on face B. It was often continuous in distribution, consisting of 5 or more strands. In addition, many particulate structures, occasionally fibrillar ones, of ridge materials were often visible in the bottoms of furrows, and a few particles were scatteredly found on the tops of crests. The ridge materials, if added together on crests and furrows, were linearly continuous in some case and discontinuous in other.
D001932:Brain Neoplasms / Q000473:pathology*; D002462:Cell Membrane; D005614:Freeze Fracturing; D006801:Humans; D007365:Intercellular Junctions; D008854:Microscopy, Electron; D009837:Oligodendroglioma / Q000473:pathology*