Immunoreactive beta-melanocyte-stimulating hormone in cerebrospinal fluid and plasma in hypopituitarism: evidence for an extrapituitary origin.
Immunoreactive beta-melanocyte-stimulating hormone (beta-MSH) was measured in the plasma of 19 patients with hypopituitarism and in the cerebrospinal fluid (CSF) of five of these patients. In neither plasma nor CSF were the beta-MSH concentrations significantly different from those in normal controls. These observations raise the possibility that beta-MSH may be produced by and secreted from neural tissue; this is supported by the findings of beta-MSH in high concentrations in many parts of the brain.
D001923:Brain Chemistry; D006801:Humans; D007018:Hypopituitarism / Q000378:metabolism*; D009074:Melanocyte-Stimulating Hormones / Q000032:analysis* / Q000097:blood / Q000134:cerebrospinal fluid
D009074:Melanocyte-Stimulating Hormones