title: Effects of prindolol on impulse formation and conduction in man.
abstract: Electrophysiologic changes produced by intravenous administration of 0.6 mg Prindolol were studied in 16 subjects with normal impulse formation and conduction. The most important changes were: sinus bradycardia, prolongation of atrial refractory periods, depression of intranodal conduction and prolongation of A-V node refractory periods. Sinus node recovery time was unchanged, and sinoatrial conduction time was only slightly increased. Intraventricular conduction time and the refractory period of the His-Purkinje system and of the bundle branches were unchanged.
mesh_terms: D001283:Atrioventricular Node / Q000187:drug effects / Q000502:physiology; D004562:Electrocardiography; D006329:Heart Conduction System / Q000187:drug effects* / Q000502:physiology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007275:Injections, Intravenous; D010869:Pindolol / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D010869:Pindolol