An in vitro study of the susceptibility of cells from a meningioma of human origin for measles virus.
A cell culture from a meningioma of human origin was found permissive for the Edmonston strain of measles virus. Virus was isolated from the supernatant of infected cell sheet as soon as 48 hr post-inoculation. Cytopathic effect, observed by light microscopy, exhibited syncitia plus intracytoplasmic and intranuclear inclusions. Electron microscopy enabled viral nucleocapsids to be observed first in the cytoplasm and secondly within the nucleus of infected cells.
D001932:Brain Neoplasms / Q000382:microbiology*; D002478:Cells, Cultured; D005260:Female; D006801:Humans; D008459:Measles virus / Q000254:growth & development*; D008579:Meningioma / Q000382:microbiology*; D008875:Middle Aged; D014779:Virus Replication