Molecular aspects of muscle contraction and regulation.
Current views regarding some aspects of the contraction of muscle and its regulation are reviewed. Recent work bearing on the segmental flexibility of myosin is related to cross-bridge movements and ATP metabolism in living muscle. Interaction of troponin with calcium, the process that initiates activation of actin-myosin interaction, is discussed in terms of Ca-induced conformational changes and protein-protein interactions.
D000199:Actins / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism; D008968:Molecular Conformation; D009119:Muscle Contraction; D009132:Muscles / Q000378:metabolism; D009218:Myosins / Q000378:metabolism; D014336:Troponin / Q000378:metabolism
D000199:Actins; D014336:Troponin; D000255:Adenosine Triphosphate; D009218:Myosins; D002118:Calcium