title: The effect of exposure rate on translocation induction in somatic and germ cells of the mouse (Mus musculus).
abstract: The effect of exposure rate on translocation induction in spermatogonia, scored as multivalents in descending spermatocytes and bone-marrow cells of the mouse (Mus musculus) was investigated 65--100 days after X-ray and gamma-ray exposures of 400 R. In the range of exposure rates studied there was a decreased in frequency in bone-marrow cells from 17.1% at 130 R/min to 4.6% at 0.0287 R/min. In spermatogonia the frequency dropped from 6.7% at 130 R/min to 1.9% at 0.0287 R/min. The data obtained for both tissues fitted a straight line when plotted against the logarithm of the exposure rate. The ratios between aberration frequencies in bone-marrow cells and spermatogonia, with a mean value of 2.74, were independent of exposure rate.
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects*; D001854:Bone Marrow Cells; D002478:Cells, Cultured; D002869:Chromosome Aberrations / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D008297:Male; D051379:Mice; D013090:Spermatocytes / Q000528:radiation effects*; D013093:Spermatogonia / Q000528:radiation effects*; D013094:Spermatozoa / Q000528:radiation effects*; D013997:Time Factors; D014178:Translocation, Genetic / Q000528:radiation effects*