[The ultrastructure of the neointima of arterial prostheses made of lyophilized human dura. Long-term results in dogs (author's transl)].
Five arterial prostheses made of lyophilized human dura (LHD) were inserted into dogs and removed after 4, 5 1/2, 13, 43, and 46 months to be studied with the electron microscope. The neointima of all grafts consisted of pseudo-endothelial cells, fibrocytes, and collagen fibrils. Additionally, 43 and 46 months after implantation smooth muscle cells and elastic microfibrils were present. Thus, the composition of the neointima was substantially identical with that of the neointima of synthetic arterial grafts and collagen-fabric ones. The clinical application of arterial prostheses of LHD, however, seems at present too early because of degenerative changes in the walls of those grafts which remained nearly 4 years in the dogs.
D000818:Animals; D001158:Arteries / Q000601:surgery* / Q000648:ultrastructure; D004285:Dogs; D004388:Dura Mater / Q000637:transplantation*; D005260:Female; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D012038:Regeneration; D013997:Time Factors
Die Ultrastruktur der Neointima arterieller Gefässprothesen aus lyophilisierter menschlicher Dura. Langzeitergebnisse bei Hunden