title: Paget's disease with spinal cord compression. Favourable course after decompression and calcitonin treatment in two cases.
abstract: Two cases with spinal cord compression due to Paget's disease (osteodystrophia deformans) are reported, which were treated with calcitonin (Salmon Calcitonin) during 12 and 24 months after decompressive laminectomy. Both presented a favourable clinical course with improvement of sensory and bladder disturbances, paraparesis and pain. Diagnostic criteria as X-ray investigation, scintigraphy of bones, biochemical parameters and the long-term treatment whith calcitonin, are discussed.
mesh_terms: D002116:Calcitonin / Q000627:therapeutic use*; D006801:Humans; D007796:Laminectomy; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D010001:Osteitis Deformans / Q000150:complications*; D011379:Prognosis; D013117:Spinal Cord Compression / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery
chemical_list: D002116:Calcitonin