Arterial-venous differences across the lungs in plasma triglyceride concentration.
Arterial-venous differences in plasma triglyceride across the lungs were determined in healthy human subjects before, during and following infusion of a soybean oil emulsion into the superior vena cava. Samples were acquired from the pulmonary and brachial arteries. A significantly greater mean concentration of triglyceride in venous as opposed to arterial blood was evident following 12 min of infusion (pless than 0.001), with a tendency for the retained lipid to be released during the postinfusion period. It could be calculated that during infusion the lungs retained about 20% of the available triglyceride, or 3 mmol/min.
D000328:Adult; D002302:Cardiac Output; D004655:Emulsions; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood* / Q000503:physiopathology; D008168:Lung / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery; D011652:Pulmonary Circulation; D011653:Pulmonary Diffusing Capacity; D011667:Pulmonary Veins; D014280:Triglycerides / Q000097:blood*
D004655:Emulsions; D014280:Triglycerides