[Role of a change in the electric conductivity of an epileptiform focus in the spread of paroxysmal activity].
In acute experiments on unanaesthetized cats a study was made of the influence of shunting a region of the cortex with a metal plate on its electrical activity and impedance. Shunting of a region of strychninization reduces the amplitude of paroxysmal oscillations in the focus and in remote regions of the cortex, reduces their frequency and produces a considerable lowering of the impedance both in the regions of the cortex between the active electrodes and between active and indifferent electrodes. Impedance of the strychninized cortex is lower than the total resistance of the intact neocortex; this testifies to the rise of conductivity in the area of strychninization, which is similar to application of a shunting plate. The data obtained corroborate the substantial role of the bioelectrical field in the development of electroencephalographic paroxysmal manifestations.
D000818:Animals; D002540:Cerebral Cortex / Q000503:physiopathology*; D004553:Electric Conductivity; D004594:Electrophysiology; D011817:Rabbits; D012640:Seizures / Q000139:chemically induced / Q000503:physiopathology*; D013331:Strychnine
D013331:Strychnine
Znachenie izmeneniia élektroprovodnosti épileptiformnogo ochaga v rasprostranenii paroksizmal'noĭ aktivnosti