In vitro responsiveness of human gastric carcinoma to pentagastrin.
The influence of pentagastrin on thymidine incorporation of five human gastric carcinomas was studied by an in vitro short-term cell suspension technique. Two of the five tumours reacted with stimulation of incorporation to the treatment. Five tumours of other aetiology did not react to similar treatment. The possibility of gastric carcinoma as a hormone-sensitive tumour is discussed.
D001943:Breast Neoplasms / Q000188:drug therapy; D002478:Cells, Cultured; D003110:Colonic Neoplasms / Q000188:drug therapy; D004273:DNA, Neoplasm / Q000096:biosynthesis; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D010418:Pentagastrin / Q000494:pharmacology*; D013274:Stomach Neoplasms / Q000188:drug therapy*; D013936:Thymidine / Q000378:metabolism
D004273:DNA, Neoplasm; D010418:Pentagastrin; D013936:Thymidine