Stoichiometry and accessibility of histone 3 sulfhydryl groups in chromatin subunits.
The accessibility of the sulfhydrl groups of histone 3(H3) in chromatin subunit particles has been investigated by reaction with p-hydroxymercuribenzoate. The resuls indicate that the carboxy-terminal regions of H3 are buried in the native particle, and suggest the presence of 2 mol of H3 per chromatin monomer.
D000818:Animals; D001665:Binding Sites; D002843:Chromatin / Q000032:analysis*; D004247:DNA / Q000032:analysis; D006657:Histones / Q000032:analysis; D006902:Hydroxymercuribenzoates; D008099:Liver; D046911:Macromolecular Substances; D008970:Molecular Weight; D011485:Protein Binding; D051381:Rats; D013438:Sulfhydryl Compounds / Q000032:analysis
D002843:Chromatin; D006657:Histones; D006902:Hydroxymercuribenzoates; D046911:Macromolecular Substances; D013438:Sulfhydryl Compounds; D004247:DNA