Weight reduction in schizophrenics by molindone.
The weight-reducing property of molindone, a recently introduced antipsychotic drug, was tested in 9 hospitalized chronic schizophrenic patients. There was an average weight loss of 7.6 kg after 3 months on molindone; most of the loss occurred during the first month. The mechanism producing this weight loss is uncertain, but a central anorexigenic effect may be an important factor.
D000328:Adult; D001067:Appetite Depressants / Q000494:pharmacology; D001519:Behavior / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects*; D002908:Chronic Disease; D005260:Female; D006760:Hospitalization; D006801:Humans; D007211:Indoles / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D008972:Molindone / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy*; D013997:Time Factors
D001067:Appetite Depressants; D007211:Indoles; D008972:Molindone