title: [Dynamics of changes in the indicators of electrolyte metabolism after surgical treatment of Cushing's syndrome].
abstract: The authors present the results of study of the state of the water-electrolyte metabolism at the early postoperative period in 58 patients suffering from Itsenko-Cushing's disease with consideration of the potassium deficiency correction. Potassium and sodium level was studied in the plasma and the erythrocytes. Besides, in 31 patients potassium and sodium content were examined in the muscular tissue obtained during the operation. Hypoglycemia was revealed in 48.2% of the cases, and hypernatriemia--in 19.0%. A reduction of potassium level in the erythrocytes was revealed in 50%, and a rise of sodium--in 52% of cases. The muscle tissue potassium level fell in parallel to the reduction of this electrolyte level in the erythrocytes. Disturbances of the electrolyte balance proved to be most pronounced at the early postoperative period in the patients given no potassium preparations. Separate use of potassium preparations, or (particularly) together with veroshpiron, prevented potassium deficiency at the early postoperative period.
mesh_terms: D000293:Adolescent; D000315:Adrenalectomy; D000328:Adult; D002648:Child; D003480:Cushing Syndrome / Q000378:metabolism / Q000601:surgery*; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006955:Hypernatremia / Q000209:etiology; D007008:Hypokalemia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000378:metabolism; D011188:Potassium / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*
chemical_list: D012964:Sodium; D011188:Potassium
vernacular_title: Dinamika izmeneniĭ pokazateleĭ elektrolitnogo obmena posle khirurgicheskogo lecheniia bol'nykh bolezn'iu Ishchenko-Kushinga