title: Metabolically induced focal seizures: hyperosmolar non-ketoacidotic hyperglycemia.
abstract: Focal epileptic activity with or without further neurological symptoms may be induced by hyperosmolar non-ketoacidotic hyperglycemia. This syndrome may develop in the course of various diseases and cerebral lesions, frequently during therapeutic dehydration. On the other hand, neurological disorders may arise as a secondary consequence of the metabolic disturbance. Based upon literature reports and eight own observations, the neurological aspects of non-ketoacidotic hyperglycemia and its therapy are described.
mesh_terms: D000138:Acidosis / Q000150:complications* / Q000188:drug therapy; D000367:Age Factors; D000368:Aged; D003128:Coma / Q000209:etiology; D003681:Dehydration / Q000150:complications / Q000188:drug therapy; D004827:Epilepsy / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D006827:Hydantoins / Q000627:therapeutic use; D006943:Hyperglycemia / Q000150:complications* / Q000188:drug therapy; D007552:Isotonic Solutions; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration
chemical_list: D006827:Hydantoins; D007552:Isotonic Solutions