title: [Ancillary chemotherapy in the primary treatment of carcinoma of the breast. On the growth pattern of carcinoma of the breast and the establishment of a new concept in treatment (author's transl)].
abstract: A prospective study of 25 cases of primary carcinoma of the breast was established. The patients were treated by radical mastectomy and lymphadenectomy followed by chemotherapy with Vincristin, Adriblastin and Endoxan. No radiotherapy was employed. During a 12 month follow-up, no patient, had recurrence or progression of the tumor. It is too early to evaluate the treatment definitively regarding survival and definite value of the method. The theoretical and experimental considerations for ancillary chemotherapy are discussed.
mesh_terms: D001943:Breast Neoplasms / Q000188:drug therapy* / Q000601:surgery; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D005860:Germany, West; D006801:Humans; D008197:Lymph Node Excision; D008408:Mastectomy; D011446:Prospective Studies; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide
vernacular_title: Adjuvante Chemotherapie in der Primärbehandlung des Mammakarzinoms. Uberiegungen zum Wachstumsverhalten des Mammakarzinoms und der Versuch eines neuen Therapienkonzepts