Selective immunoglobulin M deficiency in foals.
Selective immunoglobulin M deficiency was diagnosed in 5 foals, on the basis of reduced serum immunoglobulin M concentrations (more than 2 standard deviations below the normal mean). All 5 foals had clinical signs or lesions involving the respiratory tract. Lkebsiella sp was isolated from joint fluids, bronchial lymph nodes, or tracheal washings from the 3 foals in which such samples were available for microbiologic evaluation.
D000818:Animals; D001996:Bronchopneumonia / Q000662:veterinary; D003176:Complement C3 / Q000032:analysis; D004406:Dysgammaglobulinemia / Q000276:immunology / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000276:immunology*; D006736:Horses; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000662:veterinary*; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D008297:Male; D011014:Pneumonia / Q000662:veterinary
D003176:Complement C3; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M