Sudden onset of unilateral third nerve paresis in a patient with Cushing syndrome.
Extraocular muscle pareses in patients with Cushing syndrome are virtually always associated with a greatly enlarged pituitary tumor and with advancement on oculomotor nerves. The present report concerns a patient with a rapidly progressive adrenocorticotropic hormone (ACTH)-dependent hyperadrenocorticism and sudden onset of an unilateral third nerve paresis. The patient had no demonstrable pituitary tumor. After a total adrenalectomy and correction of hyperadrenocortisolism, his third nerve paresis subsided. Ocular paresis may occur in a patient with Cushing syndrome even in the absence of mechanical involvement of ocular nerves by a pituitary tumor.
D015065:17-Hydroxycorticosteroids / Q000652:urine; D015068:17-Ketosteroids / Q000652:urine; D000315:Adrenalectomy; D003480:Cushing Syndrome / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D003907:Dexamethasone; D006801:Humans; D008297:Male; D008875:Middle Aged; D009886:Ophthalmoplegia / Q000209:etiology*
D015065:17-Hydroxycorticosteroids; D015068:17-Ketosteroids; D003907:Dexamethasone