title: A search for species-specific antigens in the genus Penicillium.
abstract: The immunological relationship between five different species of Penicillium was examined. Organisms included in the study were P. citrinum, P. chrysogenum, P. italicum, P. notatum and P. roqueforti. These species were selected because of their frequency in nature and their ability to grow on a wide variety of substrates. Antigen extracts were prepared by culturing each organism in synthetic media. Rabbit antisera tested against the various antigen extracts by immunodiffusion indicated a cross-reactivity between P. notatum and P. chrysogenum. No cross-reactivity between other species of Penicillium was detected.
mesh_terms: D000918:Antibody Specificity; D000946:Antigens, Fungal / Q000302:isolation & purification; D010407:Penicillium / Q000276:immunology*; D013045:Species Specificity
chemical_list: D000946:Antigens, Fungal