[Changes of the blood gases following the application of naloxon (author's transl)].
74 patients, undergoing gynaecological operations under neuroleptanesthesia were subdivided into 4 groups, each receiving Naloxone in different doses postoperatively. For a longer period of time tidal volume, respiratory rate, minute ventilation, blood gas volues and pain index were recorded. From the results one can conclude that 0.1-0.2 mg Naloxone i.v. seems to be the most effective dose to reverse opiate-induced respiratory depression. The initial i.v. dose should be followed by an i.m. dose of 0.2 mg, if required.
D001784:Blood Gas Analysis; D002245:Carbon Dioxide / Q000097:blood; D055598:Chemical Phenomena; D002621:Chemistry; D005260:Female; D006801:Humans; D009270:Naloxone / Q000494:pharmacology*; D009458:Neuroleptanalgesia; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D012123:Pulmonary Ventilation; D012119:Respiration
D002245:Carbon Dioxide; D009270:Naloxone; D010100:Oxygen
Zum Verhalten der Blutgase in der postoperativen Phase nach der Applikation von Naloxon