Fracture healing in the sciatically denervated rat.
Fractures of the fibula were produced in rats with sciatic denervation. The denervated rats exhibited more rapid fracture healing than controls. Fifteen days following injury, enhanced union was measured by histologic assessment (p less than 0.001), and biomechanical testing including fracture stress (p less than 0.005), elastic modulus (p less than 0.005), strain at failure (p = 0.01) and energy to failure (p = 0.05).
D000818:Animals; D001696:Biomechanical Phenomena; D003714:Denervation; D005360:Fibula / Q000503:physiopathology*; D050723:Fractures, Bone / Q000503:physiopathology*; D051381:Rats; D012584:Sciatic Nerve / Q000503:physiopathology*; D013997:Time Factors