title: Energy deprivation in man--methodological problems and possibilities.
abstract: Various approaches to the study of physiological and behavioural effects of energy deprivation are presented and discussed. An experimental, total energy deprivation in 20 healthy human volunteers during an 11-day period, preceded and followed by 4-day control periods, is described. Potentially pathogenic reactions which occurred in spite of precautions are analysed. It is concluded that the present controlled real-life model with acute total energy deprivation serves the purpose of studying hypotheses concerning potentially pathogenic mechanisms occurring in deprivational situations under conditions of natural and man-made catastrophes.
mesh_terms: D000328:Adult; D001835:Body Weight; D003404:Creatinine / Q000097:blood; D004562:Electrocardiography; D004734:Energy Metabolism; D005215:Fasting; D005500:Follow-Up Studies; D006805:Human Experimentation; D006801:Humans; D007659:Ketones / Q000652:urine; D008297:Male; D008954:Models, Biological; D009748:Nutrition Disorders / Q000378:metabolism; D013217:Starvation
chemical_list: D007659:Ketones; D003404:Creatinine