title: Parasympathetic nerve section for control of sialorrhea.
abstract: Twenty mentally retarded patients with a considerable drooling problem underwent transtympanic sectioning of selected preganglionic parasympathetic nerve fibers to the major salivary glands. Following surgery, cessation of trouble-some sialorrhea occurred in 15 to 20 patients; but by six months postoperatively, only ten patients remained controlled. The best results obtained were in a subgroup of five patients who underwent bilateral Jacobson nerve and chorda tympani nerve section. In four of these patients, sialorrhea was controlled after a minimum follow-up of two years. Parasympathetic denervation of the major salivary glands via a transtympanic approach is offered as a primary modality of therapy in those mentally retarded patients judged to have considerable sialorrhea. Sacrifice of both chorda tympani nerves appears to enhance the surgical results.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002814:Chorda Tympani Nerve / Q000601:surgery*; D004432:Ear, Middle / Q000294:innervation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010275:Parasympathetic Nervous System / Q000601:surgery*; D011183:Postoperative Complications; D012008:Recurrence; D012469:Salivary Glands / Q000294:innervation*; D012798:Sialorrhea / Q000601:surgery*