[Repercussions of hyperthyroidism on the total cerebellar DNA contents in the rat at 6 and 35 days of age. Comparative effects of LT3 and DLT4 (author's transl)].
The total cerebellar proteins RNA and DNA contents from DLT4-and LT3-treated rats was studied at 6 and 35 days of age. The effect of injections of 5 microng/j of DLT4 is comparable to that of 25 microng of LT3 at birth, followed by 0.5 microng every 2 days. On the other hand, injection of 0.5 microng of LT3 every 3 days does not induce any significant modification of the total DNA contents in the cerebellum.
D000375:Aging; D000818:Animals; D002531:Cerebellum / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D004247:DNA / Q000378:metabolism*; D006980:Hyperthyroidism / Q000378:metabolism*; D008297:Male; D009419:Nerve Tissue Proteins / Q000378:metabolism; D012313:RNA / Q000378:metabolism; D051381:Rats; D013974:Thyroxine / Q000494:pharmacology*; D014284:Triiodothyronine / Q000494:pharmacology*
D009419:Nerve Tissue Proteins; D014284:Triiodothyronine; D012313:RNA; D004247:DNA; D013974:Thyroxine
Repercussions de l'hyperthyroäidie sur le contenu total en ADN du cervelet de rat âgé de 6 et 35 jours. Effects comparés de la LT3 et la DLT4