Epimerisation of 3beta-ol to 3alpha-ol steroid alkaloids by Nocardia restrictus.
(22S,25S)-5alpha-tomatanin-3beta-ol, N-acetyl-(22S,25S)-5alpha-tomatanin-3beta-ol, (22R,25R)-5alpha-tomatanin-3beta-ol and (22R, 25S)-22, 26-epimino-5alpha-cholestane-3beta, 16beta, 16beta-diol are transformed by Nocardia restrictus into corresponding 3alpha-ol compounds with yields from 7o to 5%.
D000470:Alkaloids / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D007535:Isomerases / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D009615:Nocardia / Q000201:enzymology*; D013251:Steroid Isomerases / Q000378:metabolism*; D014053:Tomatine / Q000378:metabolism*
D000470:Alkaloids; D014053:Tomatine; D007535:Isomerases; D013251:Steroid Isomerases