RNA:DNA ratios in human tumors.
A study has been made of the quantitative relation existing between the RNA:DNA ratios in benign and in malignant human tumors. It has been demonstrated that a significant difference (Student's t-test) existed between malignant and benign human tumors within the different groups studied: a) malignant and benign breast tumors (t=2.22, P less than 0.05); b) Hodgkin's disease in spleen and its controls (t=2.39, P less than 0.02); and c) malignant and benign thyroid tumors (t=4.23, P less than 0.01). The diagnostic value of this finding is discussed.
D001943:Breast Neoplasms / Q000032:analysis; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007938:Leukemia / Q000032:analysis; D008175:Lung Neoplasms / Q000032:analysis; D008297:Male; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000032:analysis* / Q000473:pathology; D012334:RNA, Neoplasm / Q000032:analysis*; D013964:Thyroid Neoplasms / Q000032:analysis
D004273:DNA, Neoplasm; D012334:RNA, Neoplasm