title: The effects of sedation on the impedance test battery.
abstract: Fifteen adults, hospitalized for fiberoptic endoscopy studies, were tested under two conditions using impedance audiometry. The first series of tests was conducted prior to the fiberoptic studies and sedation; the second immediately following examination, approximately 20 minutes after sedation with diazepam (Valium) and meperidine (Demerol) hydrochloride. Sedation with diazepam and meperidine failed to have a significant effect on tympanometry, static compliance, or differential loudness. These drugs were therefore considered effective sedatives for conducting impedance studies on difficult-to-test patients. This procedure is not recommended as a routine procedure and should be done only as a last resort.
mesh_terms: D000328:Adult; D000368:Aged; D001299:Audiometry / Q000379:methods*; D001309:Auditory Threshold / Q000187:drug effects; D003187:Compliance; D003975:Diazepam / Q000008:administration & dosage*; D004432:Ear, Middle; D006801:Humans; D008614:Meperidine / Q000008:administration & dosage*; D008875:Middle Aged; D012018:Reflex / Q000187:drug effects
chemical_list: D008614:Meperidine; D003975:Diazepam