title: Skin necrosis following extravasation during peripheral phlebography.
abstract: Skin necrosis is an unusual complication following venography of the legs. The authors have found only four cases in the English literature. Two cases of skin necrosis following extravasation of  contrast medium are reported. Their pathogenesis, clinical course, and treatment are discussed along with methods of prevention.
mesh_terms: D000328:Adult; D003287:Contrast Media / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010690:Phlebography / Q000009:adverse effects*; D012871:Skin Diseases / Q000139:chemically induced / Q000209:etiology*
chemical_list: D003287:Contrast Media