Glucose-6-phosphate dehydrogenase deficiency and red cell glutathione peroxidase.
The activity of glutathione peroxidase (GSH Px), glucose-6-phosphate dehydrogenase (G-6-PD), hexokinase, and glutamic oxaloacetic transaminase (EGOT) was measured in 78 blood samples. GSH Px activity was not found to correlate with hexokinase or EGOT activity, indicating that it was not a strongly age-dependent enzyme. Although modest elevations of GSH Px activity were observed in the red cells of patients with a variety of hematologic disorders, the most consistent and striking increases in activity were observed in G-6-PD-deficient subjects.
D001219:Aspartate Aminotransferases / Q000097:blood; D004912:Erythrocytes / Q000032:analysis*; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood*; D005979:Glutathione Peroxidase / Q000097:blood*; D006593:Hexokinase / Q000097:blood; D006801:Humans; D010544:Peroxidases / Q000097:blood*
D010544:Peroxidases; D005979:Glutathione Peroxidase; D001219:Aspartate Aminotransferases; D006593:Hexokinase