title: [Digoxin and beta-methyldigoxin concentrations in cerebrospinal fluid and plasma (author's transl)].
abstract: 12 patients were treated for at least two days with digoxin or beta-methyldigoxin before a lumbar punction was done for diagnostic purposes. At the same time venous blood was drawn and both samples were radioimmunologically analysed for digoxin concentration. The relationship of concentrations from plasma to cerebrospinal fluid was 2 for beta-methyldigoxin and 8 for digoxin.
mesh_terms: D002490:Central Nervous System / Q000187:drug effects; D004077:Digoxin / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D006801:Humans
chemical_list: D004077:Digoxin
vernacular_title: Konzentrationen von Digoxin und Beta-Methyldigoxin im Liquor und Plasma