Acetaminophen toxity.
A case report of an acetaminophen overdose is described, and the toxicity, clinical course and treatment of acetaminophen overdose are discussed. Treatment modalities include removal of the acetaminophen by emesis or gastric lavage, the use of activated charcoal and a saline cathartic. Several antidotes have been proposed, most notably cysteamine and acetylcysteine.
D000082:Acetaminophen / Q000506:poisoning*; D000111:Acetylcysteine / Q000627:therapeutic use; D000328:Adult; D056486:Chemical and Drug Induced Liver Injury; D003543:Cysteamine / Q000627:therapeutic use; D006801:Humans; D008099:Liver / Q000201:enzymology; D008107:Liver Diseases / Q000201:enzymology / Q000473:pathology; D008111:Liver Function Tests; D008297:Male; D009336:Necrosis; D013438:Sulfhydryl Compounds / Q000627:therapeutic use
D013438:Sulfhydryl Compounds; D000082:Acetaminophen; D003543:Cysteamine; D000111:Acetylcysteine