The contingent negative variation (CNV) and speech production: slow potentials and the area of Broca.
The lateral distribution of the CNV was investigated during conditions that required normal male and female subjects to vocalize simple English words in a CNV paradigm. In addition to a non-verbal or comparison condition (Tone-Clicks/Button Press), two word conditions presented stimulus words in either S1 or S2 positions (Word-Tone/Speak; Tone-Word/Speak) and a third condition required a one-word association to the stimulus words (Word-Tone/Speak Association). Monopolar scalp activity was collected from sites that included a location approximating Broca's speech area on the left hemisphere,  a homologous comparison site on the right hemisphere, frontal sites (F3, F4) and the vertex (Cz). Although several subjects showed some asymmetrical activity in some of the word conditions, amplitude measures based on CNV averages indicated no consistent lateralization effects over the left hemisphere prior to word vocalizaiton. Negative pretrial shifting was suspected in those conditions in which words appeared as S1 signals.
D000161:Acoustic Stimulation; D001244:Association; D001921:Brain / Q000502:physiology*; D003265:Contingent Negative Variation; D004594:Electrophysiology; D005071:Evoked Potentials; D005625:Frontal Lobe / Q000502:physiology; D007839:Functional Laterality; D010775:Photic Stimulation; D013060:Speech / Q000502:physiology*