title: [Theophylline and theobromine derivatives of nitrogen heterocyclic compounds].
abstract: 7-Theophylline derivatives with 4,6-dihydroxy-5-pyrimidinyl-, 3-oxopiperazinylmethyl- and 4-methyl-3,5-dioxopiperazinylmethyl substituents are described: they can be viewed as structural analogues of a nucleic base pair in the Hoogsteen arrangement; theobromine could be converted into the 1-(3,5-dioxo-4-pyrazolidinyl) derivative, similarly analogous to a base pair in the Watson-Crick arrangement.
mesh_terms: D006571:Heterocyclic Compounds; D007202:Indicators and Reagents; D009584:Nitrogen; D013805:Theobromine / Q000138:chemical synthesis*; D013806:Theophylline / Q000031:analogs & derivatives / Q000138:chemical synthesis*
chemical_list: D006571:Heterocyclic Compounds; D007202:Indicators and Reagents; D013806:Theophylline; D009584:Nitrogen; D013805:Theobromine
vernacular_title: Teofillin- e teobromin derivati di eterocicli azotati