Incorporation of [U-C14-A1-glucose in vitro by different parts of the rabbit Fallopian tube and uterus.
The in vitro incorporation of E1U-C14]-glucose by ampullary and isthmic segments of the Fallopian tube and the uterus was determined in the intact (estrous), ovariectomized, ovariectomized plus estrogen and ovarietcomized plus estrogen + progesterone treated rabbit. In the intact animal the ampulla incorporated glucose at a faster rate than the isthmus; uterine uptake is minimal. Ovariectomy reduced the rate of incorporation below normal values in all the tissues. EDP (estradiol dipropionate) administered to ovariectomized rabbit increased the incorporation rate. Progesterone antagonized the EDP-induced uptake. The relative rate and pattern of incorporation by the three tissues were, however, determined by the dosage of estrogen and the estrogen/progesterone ratio.
D000818:Animals; D002369:Castration; D004958:Estradiol / Q000494:pharmacology; D005187:Fallopian Tubes / Q000187:drug effects / Q000378:metabolism*; D005260:Female; D005947:Glucose / Q000378:metabolism*; D011374:Progesterone / Q000494:pharmacology; D011817:Rabbits; D014599:Uterus / Q000187:drug effects / Q000378:metabolism*
D011374:Progesterone; D004958:Estradiol; D005947:Glucose