title: Inhibitory effects of ATP on platelet aggregation: cation interaction and shape change.
abstract: Adenosine triphosphate (ATP) has more than one effect in its inhibition of platelet aggregation. In addition to its direct competition with adenosine diphosphate (ADP), ATP may suppress the aggregation mediated via a cation interaction and a restoration of platelet shape.
mesh_terms: D000244:Adenosine Diphosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism / Q000494:pharmacology*; D001667:Binding, Competitive; D001792:Blood Platelets / Q000166:cytology / Q000187:drug effects; D002118:Calcium / Q000494:pharmacology; D002413:Cations, Divalent; D006801:Humans; D066298:In Vitro Techniques; D008274:Magnesium / Q000494:pharmacology; D010974:Platelet Aggregation / Q000187:drug effects*; D013696:Temperature; D013997:Time Factors
chemical_list: D002413:Cations, Divalent; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D008274:Magnesium; D002118:Calcium