title: Purified carbon as a tissue replacement.
abstract: Tissue reactivity to carbon cloth, graphite cloth and vitreous carbon in the solid was studied in dogs. The materials were found to be quite inert and caused no inflammatory reaction or sensitivity changes in the dogs' tissues. No unusual changes were noted on the hemopoietic or enzyme systems. The materials are probably the best biocompatible substances known and seem to meet the major criteria for tissue replacements.
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001807:Blood Vessel Prosthesis; D001842:Bone and Bones / Q000033:anatomy & histology / Q000601:surgery; D002244:Carbon; D004285:Dogs; D005205:Fascia / Q000033:anatomy & histology; D000071938:Fasciotomy; D006108:Graphite; D006350:Heart Valve Prosthesis; D007595:Joint Prosthesis; D013784:Textiles
chemical_list: D001672:Biocompatible Materials; D002244:Carbon; D006108:Graphite