Zinc binding: a difference between human and bovine milk.
Gel chromatography indicated that most of the zinc in cow's milk was associated with high-molecular-weight fractions, whereas zinc in human milk was associated with low-molecular-weight fractions. A species difference in zinc-binding ligands may explain why symptoms of the genetic disorder of zinc metabolism, acrodermatitis enteropathica, can be alleviated by feeding human but not cow's milk.
D000169:Acrodermatitis / Q000378:metabolism; D000818:Animals; D002417:Cattle; D006801:Humans; D007408:Intestinal Absorption; D008024:Ligands; D008892:Milk / Q000378:metabolism*; D008894:Milk Proteins / Q000378:metabolism*; D008895:Milk, Human / Q000378:metabolism*; D008970:Molecular Weight; D011485:Protein Binding; D015032:Zinc / Q000378:metabolism*
D008024:Ligands; D008894:Milk Proteins; D015032:Zinc