[Comparative analysis of the clinico-constitutional and premorbid features of epilepsy in inbred and outbred families].
By means of clinico-catamnestical and anthropological methods the author examined 162 epileptic patients in the initial period (up to 5 years) and 473--in the florid period of the disease (5--24 years). The author demonstrates distinct clinical (the traits of the onset, development of the process, personality changes, invalidization), morphological (dysgenesia) and premorbid characterological and intellectual traits in patients of consanguineous and nonconsanguineous families. The results demonstrate a correlation between the fenotypical traits of epilepsy and the constitutional morphological and premorbid features. The achieved data point to the necessity of a differentiated approach to therapeutical measures and sociolabour rehabilitation in patients of consanguineous and nonconsanguineous families.
D000293:Adolescent; D000328:Adult; D001824:Body Constitution; D002648:Child; D002675:Child, Preschool; D000013:Congenital Abnormalities / Q000150:complications; D004827:Epilepsy / Q000150:complications / Q000235:genetics*; D005260:Female; D006801:Humans; D007178:Inbreeding; D008607:Intellectual Disability / Q000150:complications; D008297:Male; D008569:Memory Disorders / Q000150:complications; D011599:Psychopathology; D012917:Social Adjustment; D014937:Work
Sravnitel'nyĭ analiz kliniko-konstitutsional'nykh i premorbidnykh osobennosteĭ épilepsii v inbrednykh i autbrednykh sem'iakh