[Cyclic hydrazides. III. Synthesis and anti-inflammatory activity of 2-amino-3,4-dihydroisoquinolin-1(2H)-one].
The synthesis and the antiinflammatory activity of of 2-amino-3,4-dihydroisoquinolin-1(2H)-one and of a series of its derivatives on the amino function are described. Some of theses new componds show high activity in inhibiting the carrageenin oedema and granuloma formation in rats.
D000700:Analgesics / Q000138:chemical synthesis; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis*; D001241:Aspirin; D007546:Isoquinolines / Q000138:chemical synthesis*; D010653:Phenylbutazone; D051381:Rats
D000700:Analgesics; D000893:Anti-Inflammatory Agents; D007546:Isoquinolines; D010653:Phenylbutazone; D001241:Aspirin
Idrazide cicliche. Nota III - Sintesi ed attività antiinfiammatoria di 2-amino-3,4,diidroisochinolin-1(2H)-oNI