[Lipid peroxidation and degeneration of the retinal photoreceptors in rats with avitaminosis E].
Alimentary E-avitaminosis in rats was accompanied (in vivo) by a sharply intensified formation of the lipid peroxidation products (hydroperoxides, dialkylperosides, "intermolecular links") in the retina and by degeneration of photoreceptors (chiefly of the external rod segment layer). Discussion of the experimental data obtained is based upon the views on the antioxidant alpha-tocopherol action mechanism in vivo.
D000818:Animals; D050356:Lipid Metabolism; D008297:Male; D010545:Peroxides / Q000096:biosynthesis*; D010786:Photoreceptor Cells; D051381:Rats; D012160:Retina / Q000378:metabolism* / Q000473:pathology; D012162:Retinal Degeneration / Q000209:etiology* / Q000473:pathology; D014811:Vitamin E Deficiency / Q000150:complications* / Q000378:metabolism
D010545:Peroxides
Perekisnoe okislenie lipidov i degeneratsiia fotoretseptorov v setchatke krys pri E-avitaminoze