[Effect of a polysaccharide-contaning preparation from El Tor vibrions on the phagocytic activity of leukocytes and on the lysozyme titer].
The dynamics of changes in some indices of the natural immunity of mice treated with EL-Tor vibrio preparations in doses of 50 and 500 gemma/mouse was studied. The blood for analysis was taken from the mice 24 hours, 3, 7 and 10 days after the preparation administration. The results of the study showed that administration of the polysaccharide-containing preparations from El-Tor vibrios in doses of 50 and 500 gemma/mouse was accompanied by some shifts in the regulatory mechanisms: suppression of the serum lysozyme activity on the 1st and 3rd days and its stimulation on the 7th and 10th days. The percentage of phagocytosis and its completeness increased. The indices of phagocytosis and its completeness by the respective periods decreased.
D000818:Animals; D007111:Immunity, Cellular / Q000187:drug effects; D007962:Leukocytes / Q000187:drug effects* / Q000276:immunology; D051379:Mice; D009113:Muramidase / Q000097:blood*; D010587:Phagocytosis / Q000187:drug effects*; D011135:Polysaccharides, Bacterial / Q000494:pharmacology*; D013997:Time Factors; D014734:Vibrio cholerae
D011135:Polysaccharides, Bacterial; D009113:Muramidase
Vliianie polisakharidsoderzhashchego preparata iz vibrionov El'-Tor na fagotsitarniu aktivnost' leĭkotsitov i titr lizotsima