[Post-traumatic regeneration of rat skin with stimulation under conditions of gravitational stress].
Albino rats were subjected to multiple gravitation stress (11units) before infliction wounds. A marked vascular reaction was noted in the wound contents at the early observation period. The appearance and differentiation of granulation and epidermis proliferation periods were delayed. Healing the wound occurred on the 30th day (on the 15th--18th day in controls). Administration of the skin tissue extract (prepared by Filatory's method) under these conditions, simultaneously with the wound infliction and up to their healing sharply reduced the vascular reaction, accelerated the granulation differentiation and the epithelialization of the wound; in respect to the character and the periods of tissue differentiation development the restoration process thus approached the course of the post-traumatic skin regeneration under usual conditions.
D000818:Animals; D064987:Cell- and Tissue-Based Therapy; D006112:Gravitation; D051381:Rats; D012867:Skin / Q000293:injuries* / Q000473:pathology; D013312:Stress, Physiological / Q000150:complications*; D014945:Wound Healing
Posttravmaticheskaia regeneratsiia kozhi krys pri stimuliatsii v usloviiakh gravitatsionnoĭ peregruzki