title: Circadian rhythms in the cutaneous reactivity to histamine and selected antigens, including phase relationship to urinary cortisol excretion.
abstract: Data show that intradermal skin reactions to histamine, house dust and grass pollen extracts follow a prominent circadian pattern, the response elevated in the afternoon, peaking in the evening and with a morning trough. Urinary hydrocortisone excretion curves exhibit agreement in antiphase timing.
mesh_terms: D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000494:pharmacology*; D002940:Circadian Rhythm; D004391:Dust; D004890:Erythema / Q000209:etiology; D005260:Female; D006632:Histamine / Q000494:pharmacology*; D006801:Humans; D006854:Hydrocortisone / Q000652:urine*; D006967:Hypersensitivity; D008297:Male; D011058:Pollen; D012867:Skin / Q000187:drug effects*; D012882:Skin Tests
chemical_list: D000485:Allergens; D004391:Dust; D006632:Histamine; D006854:Hydrocortisone