Erythrocyte electrolyte content and sodium efflux in chronic renal failure.
The cation content of the eythrocyte was studied in 36 patients with chronic renal failure; A normal or high erythrocyte potassium was found. Erythrocytes sodium values showed a wide range, from very high to very low, and the rate constant for Na efflux was found to be higher than normal. The interpretation of these findings is discussed. It is suggested that the higher than normal. The interpretation of these findings is discussed. It is suggested that the high erythrocyte K content may reflect abnormal total body K, may be explained on the basis of a young red cell population or may be related to abnormal function of the erythrocyte cation pump. It is probable that the development of these changes in chronic renal failure depends on many factors.
D000293:Adolescent; D000328:Adult; D001692:Biological Transport; D001794:Blood Pressure; D004573:Electrolytes / Q000097:blood*; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000188:drug therapy; D008297:Male; D008750:Methyldopa / Q000627:therapeutic use; D008875:Middle Aged; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood*; D014508:Urea / Q000097:blood
D004573:Electrolytes; D008750:Methyldopa; D005665:Furosemide; D014508:Urea; D012964:Sodium; D011188:Potassium