Blindness in a patient with malignant histiocytosis.
Malignant histiocytosis (MH) is a rapidly fatal systemic disease for which there is no adequate therapy. A case of MH with involvement of both eyes resulting in bilateral blindness is presented. Infiltration with malignant cells was seen in the ciliary bodies at autopsy. Attempts at treatment for this complication are discussed.
D000328:Adult; D001766:Blindness / Q000209:etiology*; D001853:Bone Marrow / Q000473:pathology; D002555:Cerebrospinal Fluid / Q000166:cytology; D002924:Ciliary Body / Q000473:pathology; D005134:Eye Neoplasms / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D007958:Leukocyte Count; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000150:complications* / Q000473:pathology; D008297:Male