title: Enhancing the expression of flavor neophobia: some effects of the ingestion-illness contingency.
abstract: Four experiments investigating factors contributing to enhanced ingestional neophobia are reported. Rats administered lithium chloride following ingestion of a novel coffee solution showed an enhanced neophobia reaction to vinegar and casein. This enhancement was specific to the novelty of both the conditioning and test fluids and was not observed in animals receiving noncontingent toxicosis. Poisoning alone, however, mediated a nonspecific fluid suppression that persisted for approximately two drinking sessions following treatment. In contrast to other experiments, the operation of generalization was detected only when a novel flavor was the test fluid, suggesting that neophobia enhancement is at least partially mediated by a conditioned novelty aversion resulting from the novel flavor-lithium contingency.
mesh_terms: D000818:Animals; D001244:Association; D001362:Avoidance Learning; D002364:Caseins; D003069:Coffee; D003216:Conditioning, Operant; D004327:Drinking Behavior / Q000187:drug effects; D005106:Exploratory Behavior; D005793:Generalization, Psychological; D008094:Lithium / Q000506:poisoning*; D008297:Male; D051381:Rats; D013649:Taste
chemical_list: D002364:Caseins; D003069:Coffee; D008094:Lithium