Interaction of DNA with anti-cancer drugs: copper-thiosemicarbazide system.
The interaction of copper-thiosemicarbazide complexes with DNA was investigated using ultraviolet and infrared spectroscopy. Evidence for the interaction of the complexes with nucleic acid bases and with the phosphate group is presented.
D000970:Antineoplastic Agents; D055598:Chemical Phenomena; D002621:Chemistry; D003300:Copper; D004247:DNA; D012663:Semicarbazides; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000970:Antineoplastic Agents; D012663:Semicarbazides; D003300:Copper; D004247:DNA