title: Molecular aspects of muscle contraction and regulation.
abstract: Current views regarding some aspects of the contraction of muscle and its regulation are reviewed. Recent work bearing on the segmental flexibility of myosin is related to cross-bridge movements and ATP metabolism in living muscle. Interaction of troponin with calcium, the process that initiates activation of actin-myosin interaction, is discussed in terms of Ca-induced conformational changes and protein-protein interactions.
mesh_terms: D000199:Actins / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism; D008968:Molecular Conformation; D009119:Muscle Contraction; D009132:Muscles / Q000378:metabolism; D009218:Myosins / Q000378:metabolism; D014336:Troponin / Q000378:metabolism
chemical_list: D000199:Actins; D014336:Troponin; D000255:Adenosine Triphosphate; D009218:Myosins; D002118:Calcium