[Treatment of anemia in pregnancy].
In a therapeutic comparative study two trial-groups (1 and 2) of 30 pregnant women each suffering from iron deficiency anemia of light degree received randomly selected a combination of ferrous succinate and multivitamins (Multibionta-Eisen) or a combination of ferrous sulfate and folic acid (preparations ES). By both medications the decrease of hemoglobin, red blood count and hematocrit could be stopped and a re-increase of these values was seen afterwards. There was no significant differences in response between Multibionta-Eisen and ES. A significant increase of Hb, RBC and Hc as compared prior to treatment was limited to group 2. Possible causes for the non-significant results of group 1 are discussed. The results of the study are demonstrating a certain superiority of preparation ME. This combination showed at least equal efficiency as preparation ES in spite of a smaller iron dosage and was well tolerated without exception. Subjective complaints may be better improved by Multibionta-Eisen.
D000747:Anemia, Hypochromic / Q000188:drug therapy*; D003967:Diarrhea / Q000139:chemically induced; D004338:Drug Combinations; D004341:Drug Evaluation; D004361:Drug Tolerance; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007501:Iron / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D009325:Nausea / Q000139:chemically induced; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D014815:Vitamins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use
D004338:Drug Combinations; D014815:Vitamins; D005492:Folic Acid; D007501:Iron
Zur Behandlung der Schwangerschaftsanämie