Irradiation failures in cancer of the larynx.
A series of 116 laryngeal carcinomas treated definitively with irradiation over a 9 1/2-year period is presented. By preliminary follow-up, there have been 20 recurrences, for an initial treatment failure rate of 17%. Of the 20 patients with recurrence, 16 had salvage surgical procedures. Four of the 16 surgical wounds (25%) presented complications. Eleven of the 16 patients having salvage attempts are thus far free of disease. The initial treatment failure rate of 17% has thus been lowered to 7.8% at preliminary follow-up.
D005402:Fistula / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D010614:Pharynx; D011183:Postoperative Complications