[Electron microscopic study of the seminiferous tubules of white rats exposed to boric acid].
Boric acid in a dose of 1 g/kg was given orally to albino rats for a period of 2 weeks, daily. Changes in the nucleus and the cytoplasm of both the spermatozoids and spermatides were revealed at the early stages of their formation. The appearance of numerous multinuclear cells with an even and odd number of nuclei (from 2 to 10 and over) was noted. The formation of multinuclear cells can be apparently attributed to the action of boric acid on the prolonged processes of meiotic division of the spermatogenic epithelium cells (spermatocytes, spermatides).
D000818:Animals; D000988:Antispermatogenic Agents; D001888:Boric Acids / Q000494:pharmacology*; D002467:Cell Nucleus / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D013087:Spermatids / Q000187:drug effects; D013090:Spermatocytes / Q000187:drug effects; D013091:Spermatogenesis / Q000187:drug effects*; D013094:Spermatozoa / Q000187:drug effects* / Q000648:ultrastructure
D000988:Antispermatogenic Agents; D001888:Boric Acids
Elektronno-mikroskopicheskoe issledovanie semennykh kanal'tsev belykh krys pri vozdeĭstvii bornoĭ kisloty