The effect of the distal splenorenal shunt on hypersplenism.
Twenty-four patients with leukopenia and/or thrombocytopenia improved these deficiencies after distal splenorenal shunts. The average white blood cell count for 23 neutropenic patients increased by an average 1000 cells/cu.mm p less than .01. The average platelet count for 13 thrombocytopenic patients increased by more than 40,000, p less than .02. Analysis of the data showed that patients older than 50 years, with a history of alcoholic liver disease and sinusoidal hypertension greater than 15mm Hg were most likely to correct leukocyte and platelet defects after distal splenorenal shunts.
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications; D001792:Blood Platelets; D005260:Female; D006801:Humans; D006971:Hypersplenism / Q000150:complications / Q000601:surgery*; D006975:Hypertension, Portal / Q000150:complications; D007958:Leukocyte Count; D007970:Leukopenia / Q000150:complications; D008103:Liver Cirrhosis / Q000150:complications; D008297:Male; D008875:Middle Aged; D012082:Renal Veins / Q000601:surgery*; D013162:Splenic Vein / Q000601:surgery*; D013921:Thrombocytopenia / Q000150:complications