title: [Diagnosis of the placental function with special reference to the pregnancy-specific protein SP-1].
abstract: Following a description of the three different functions of the placenta (respiratory, nutritive, endocrine) and their failures the most common function tests are presented. Special emphasis is put on the evaluation of a recently described pregnancy-specific protein (SP1) in the maternal serum. The amount of the substance produced by the placenta correlates well with the fetal weight and well-being in cases of EPH-gestosis and idiopathic placental insufficiency; correlation was not as well in mild EPH-gestosis, diabetes and RH-incompatibility. The validity of measuring SP1-production seems to be similar to that of HPL. The method of quantitative determination is simple and possible even in a smaller hospital.
mesh_terms: D004964:Estriol / Q000652:urine; D005260:Female; D006801:Humans; D010922:Placenta Diseases / Q000175:diagnosis*; D010926:Placental Hormones / Q000032:analysis* / Q000096:biosynthesis; D010927:Placental Insufficiency / Q000175:diagnosis*; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000378:metabolism; D014327:Trophoblasts / Q000378:metabolism
chemical_list: D010926:Placental Hormones; D004964:Estriol
vernacular_title: Zur Diagnostik der Plazentafunktion mit besonderer Berücksichtigung des schwangerschaftsspezifischen Proteins SP-1