title: Hageman complement and factor.
abstract: Complement components are activated by immunologic and non-immunologic mechanisms through various plasma protein systems such as immunoglobulins, properdin, plasmin, thrombin and Hageman factor. The activation of Hageman factor, followed by complement cleavage leading to liberation of various chemical mediators, can be initiated by exposure of negatively charged tissue components due to trauma and infection.
mesh_terms: D001777:Blood Coagulation; D003165:Complement System Proteins / Q000378:metabolism / Q000502:physiology*; D005174:Factor XII / Q000502:physiology*; D005342:Fibrinolysis; D006801:Humans; D007109:Immunity; D007074:Immunoglobulin G / Q000378:metabolism; D007075:Immunoglobulin M / Q000378:metabolism; D007705:Kinins / Q000378:metabolism; D010447:Peptide Hydrolases / Q000502:physiology; D011414:Properdin / Q000502:physiology
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007705:Kinins; D011414:Properdin; D005174:Factor XII; D003165:Complement System Proteins; D010447:Peptide Hydrolases