Physical retardation is associated with ring chromosome mosaicism: 46, XX,r(10)/45, XX,10 minus.
Cytogenetic analysis of peripheral leucocytes of a 9-year-old girl presenting with retardation of physical development indicated mosaicism for a ring 10 chromosome. Serum aspartate transaminase was within normal limits. A survey of eight markers failed to show syntenic relations with chromosome 10.
D001219:Aspartate Aminotransferases; D002648:Child; D002906:Chromosomes, Human, 6-12 and X; D003593:Cytoplasm / Q000201:enzymology; D005260:Female; D006801:Humans; D009030:Mosaicism
D001219:Aspartate Aminotransferases