title: [Isolation and partial characterization of (PAF) platelet-activating-factor].
abstract: Platelet-activating-factor is a new mediator of anaphylaxis released in numerous mammalian species from basophils and mastocytes by antigens, anti-IgE antiserum, ionophore A 23187, C3a, C5a and neutrophil cationic protein. It is probably a lyso-1-phosphatidylcholine, as evidenced by structural studies isomg phospholipases. It may explain the involvement of platelets in immunopathology.
mesh_terms: D000818:Animals; D001491:Basophils; D001779:Blood Coagulation Factors; D010974:Platelet Aggregation; D013552:Swine
chemical_list: D001779:Blood Coagulation Factors
vernacular_title: Isolement et caractérisation partielle du " platelet-activating-factor " (PAF)