Panniculitis of the legs with urate crystal deposition.
Dark red nodules that drained an opaque amber liquid developed on the extensor surfaces of both legs in a 69-year-old woman receiving furosemide and spironolactone for congestive heart failure. In addition to asymptomatic cholelithiasis, the serum amylase, lipase, and uric acid levels were elevated. Other skin signs and joint manifestations of gout were absent. A biopsy revealed a granuloma with the needle-like crystals characteristic of gout.
D000368:Aged; D001168:Arthritis / Q000150:complications; D003937:Diagnosis, Differential; D005260:Female; D005665:Furosemide / Q000627:therapeutic use; D006073:Gout / Q000175:diagnosis* / Q000178:diet therapy; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D008049:Lipase / Q000097:blood; D012867:Skin / Q000473:pathology; D012877:Skin Manifestations; D013148:Spironolactone / Q000627:therapeutic use; D014527:Uric Acid / Q000097:blood*
D014527:Uric Acid; D013148:Spironolactone; D005665:Furosemide; D008049:Lipase