Neuronal accumulation and metabolism of 3H-1-norepinephrine in rat portal vein: evidence in relation to possible uneven alpha receptor distribution.
The rate of accumulation and metabolism of 3H-1-norepinephrine in the neuronal plexus of rat portal vein produces a small transmitter concentration gradient across the longitudinal smooth muscle layer which cannot account for the prejunctional supersensitivity observed and suggests localization of the alpha-adrenergic receptors adjacent to the nerve plexus.
D000818:Animals; D001692:Biological Transport; D003042:Cocaine / Q000494:pharmacology; D007700:Kinetics; D008297:Male; D009474:Neurons / Q000187:drug effects / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism*; D011169:Portal Vein / Q000294:innervation*; D051381:Rats
D003042:Cocaine; D009638:Norepinephrine