title: Male infertility and 21/1 translocation.
abstract: Cultured blood leukocytes of a 27-year-old infertile white man displayed evidence of an A/G translocation. All cells showed an identical abnormal karotype, 46, XY, t(1p-;21q+). The chromosome abnormality, a proposed mechanism for its production, and related chromosome translocations are discussed.
mesh_terms: D000328:Adult; D002869:Chromosome Aberrations; D002900:Chromosomes, Human, 1-3; D002904:Chromosomes, Human, 21-22 and Y; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D007621:Karyotyping; D008297:Male; D014178:Translocation, Genetic