title: Electrical properties and active solute transport in rat small intestine. II. Conductive properties of transepithelial routes.
abstract: The transepithelial resistance, the cell membrane resistance and the ratio of resistances of the serosal (baso-lateral) to the mucosal (brush border) cell membrane were measured in rat duodenum, jejunum and ileum by means of microelectrode techniques. These measured values were not affected in the presence of actively transported solutes in the mucosal bathing fluid. Contribution of an electrical conductance through the extracellular shunt pathway to the total transepithelial conductance was quantitatively estimated using an electrically equivalent circuit analysis. These values estimated in respective tissues of small intestine were approx. 95% of the total transepithelial conductance, remaining unaffected by an active solute transport. From these data, the changes in emf's of the mucosal and serosal membrane induced by D-glucose or glycine were separately evaluated.
mesh_terms: D000818:Animals; D001693:Biological Transport, Active; D004386:Duodenum / Q000502:physiology; D004553:Electric Conductivity; D004847:Epithelial Cells; D004848:Epithelium / Q000502:physiology; D005260:Female; D005947:Glucose / Q000378:metabolism*; D005998:Glycine / Q000378:metabolism*; D007082:Ileum / Q000502:physiology; D007413:Intestinal Mucosa / Q000378:metabolism / Q000502:physiology*; D007421:Intestine, Small / Q000378:metabolism / Q000502:physiology*; D007583:Jejunum / Q000502:physiology; D008297:Male; D008433:Mathematics; D008564:Membrane Potentials; D008839:Microelectrodes; D051381:Rats
chemical_list: D005947:Glucose; D005998:Glycine