title: [Esophageal cancer in Ille-et-Vilaine in relation to levels of alcohol and tobacco consumption. Risks are multiplying].
abstract: A retrospective case-control study of 200 male cases of oesophageal cancer and 778 population controls has been carried out in Ille-et-Vilanine (France). The logarithms of the relative risks of developing the disease increase linearly with daily consumption of alcohol and tobacco independently. The combined effect of both fit with a multiplicative model which is proposed. This model could be applicable to other situations. It explains the sex ratio and the urban/rural differences observed in Ille-er-Vilaine. The practical implications for public health purposes are briefly discussed.
mesh_terms: D000328:Adult; D000368:Aged; D000434:Alcoholic Beverages / Q000009:adverse effects; D000437:Alcoholism / Q000150:complications*; D004938:Esophageal Neoplasms / Q000209:etiology*; D005260:Female; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D012424:Rural Population; D012737:Sex Factors; D012907:Smoking / Q000150:complications*; D014505:Urban Population
vernacular_title: Le cancer de l'oesophage en Ille-et-Vilaine en fonction des niveaux de consommation d'alcool et de tabac. Des risques qui se multiplient