[Impulse cytophotometric studies in cytologically suspicious cervical smears].
187 women with cytologically suspicious cervical smears (Papanicolaou III to V) were investigated by 387 pulse cytophotometric (ICP) measurements. Within the Papanicolaou III group a significantly higher 4c-peak was seen in cases with only one ICP-investigation if we had histologically pathological findings (dysplasia, carcinoma) as contrastes with clinically and cytologically regressive cases. In repeated ICP-investigations we found in group Papanicolaou III (histol.: dysplasia, carcinoma) as well as in group Papanicolaou IV and V a significantly higher mean 4c-height than in only once investigated cases. Within a ICP-series the maximal 4c-height is most representative. The security of diagnosis is raising with repeating ICP-investigations. Here it is a valuable diagnostic aid especially in suspicious cases. All abnormal ICP-findings must be controlled for a long time, even with normal cytological smears. At last, the circumstances causing false negative ICP-results are discussed.
D002467:Cell Nucleus; D004273:DNA, Neoplasm / Q000378:metabolism; D005260:Female; D006801:Humans; D008403:Mass Screening; D065006:Papanicolaou Test; D010783:Photometry / Q000379:methods*; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000517:prevention & control; D014626:Vaginal Smears
D004273:DNA, Neoplasm
Impulszytophotometrische Untersuchungen bei zytologisch suspekten Zervixsekreten