title: Studies on ovine placental lactogen secretion by homologous radioimmunoassay.
abstract: The concentrations of ovine placental lactogen (oPL) have been determined in maternal plasma, umbilical cord plasma, and allantoic fluid by an homologous radioimmunoassay for oPL which is sensitive to 0-1 ng hormone. Ovine placental lactogen was first detected in maternal plasma at 41-50 days of gestation and reached a peak concentration of 2547 +/- 226 (S.E.M.) ng/ml at 121-130 days in ewes with singleton gestations. The oPL concentration in cord plasma was 336-4 +/- 60-3 ng/ml and in allantoic fluid was 29-6 +/- 6-4 ng/ml. After surgical removal of the placenta, oPL disappeared from maternal plasma with a half-life of 29-1 +/- 1-3 min.
mesh_terms: D000482:Allantois / Q000378:metabolism; D000818:Animals; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D010920:Placenta / Q000378:metabolism*; D010928:Placental Lactogen / Q000097:blood / Q000378:metabolism*; D011247:Pregnancy; D011863:Radioimmunoassay; D012756:Sheep / Q000378:metabolism*; D013997:Time Factors
chemical_list: D010928:Placental Lactogen