title: A nitrosamide-specific detector for use with high-pressure liquid chromatography.
abstract: A highly specific automated method for identification of nitrosamides has been developed for use in conjuction with reversed-phase high-pressure liquid chromatography. The method is based on the well-known Griess reagent, and is capable of sensitivities of 0.5 nmoles of injected nitrosamide in most cases. The method may be used for analysis of nitrite, nitrosamides, nitrosocarbamates, and alkylnitrites.
mesh_terms: D000478:Alkylation; D000577:Amides / Q000032:analysis; D001322:Autoanalysis / Q000295:instrumentation; D002219:Carbamates / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D007202:Indicators and Reagents; D009602:Nitrosamines / Q000032:analysis*; D009603:Nitroso Compounds / Q000032:analysis; D009607:Nitrosourea Compounds / Q000032:analysis
chemical_list: D000577:Amides; D002219:Carbamates; D007202:Indicators and Reagents; D009602:Nitrosamines; D009603:Nitroso Compounds; D009607:Nitrosourea Compounds