Macromolecular drugs.
Some principles at the basis of the present or potential interest of pharmacologically active synthetic polymers are discussed, together with some chemical aspects of a proper design of these polymers. The synthesis and properties of heparin complexing polymers, prostaglandin releasing polymers, and nicotinic acid releasing polymers are described.
D001665:Binding Sites; D006493:Heparin / Q000138:chemical synthesis; D046911:Macromolecular Substances; D008970:Molecular Weight; D009539:Nicotinic Acids / Q000138:chemical synthesis; D011108:Polymers / Q000138:chemical synthesis*; D011453:Prostaglandins / Q000138:chemical synthesis; D012995:Solubility
D046911:Macromolecular Substances; D009539:Nicotinic Acids; D011108:Polymers; D011453:Prostaglandins; D006493:Heparin