Selective coronary embolization in closed-chest dogs.
A method is described for occluding a branch of the canine left coronary arterial system, without the use of X-ray equipment or the need for a surgical thoracotomy. For the creation of experimental myocardial infarction, either a solid embolus or a diffusible medium is introduced into the coronary vessels via a rigid cannula which is inserted through a carotid artery. This technique produces infarcts of reproducible size with a minimum of equipment and surgical complication.
D000818:Animals; D002339:Carotid Arteries; D002404:Catheterization / Q000379:methods; D003331:Coronary Vessels; D004195:Disease Models, Animal; D004285:Dogs; D009203:Myocardial Infarction