A random walk model of cellular kinetics.
The sorting out of biological cell mixtures into clusters of one cell type is modelled as a consequence of random cell and cluster motion, during which cells of like type cohere upon collision. After a description of the model and its motility rules, the results of several computer simulation studies are analysed and compared with both laboratory data and certain theoretical predictions. The model is found to be more biologically realistic than previous models with similar results. Suggestions for further reserach are discussed. An Appendix contains details about the data structures and algorithms employed in the simulation.
D002448:Cell Adhesion; D002465:Cell Movement; D002468:Cell Physiological Phenomena; D002469:Cell Separation; D003201:Computers; D007700:Kinetics; D008954:Models, Biological