title: Contact activation of factor XI: evidence that the primary role of contact activation cofactor (CAC) is to facilitate the activation of factor XII.
mesh_terms: D002846:Chromatography, Affinity; D005172:Factor XI / Q000302:isolation & purification / Q000378:metabolism*; D005174:Factor XII / Q000378:metabolism*; D006801:Humans; D007704:Kininogens / Q000378:metabolism*; D014357:Trypsin / Q000378:metabolism
chemical_list: D007704:Kininogens; D005174:Factor XII; D005172:Factor XI; D014357:Trypsin