title: Severe metabolic acidosis as a complication of intravenous tetracycline therapy.
abstract: Tetracycline generally is believed to be a safe drug with relatively minor side effects. Serious irreversible renal damage and metabolic acidosis can occur in patients with azotemia. While the exact mechanism is unknown, the commonly reported nephrotoxic and metabolic effects of tetracycline are reviewed and an illustrative case is presented.
mesh_terms: D000138:Acidosis / Q000139:chemically induced*; D058186:Acute Kidney Injury / Q000139:chemically induced; D000368:Aged; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D011247:Pregnancy; D013752:Tetracycline / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D013752:Tetracycline