Serum thyrotrophin determination on day 5 of life as screening procedure for congenital hypothyroidism.
In 327 newborns cord blood thyroxine (T4) was 11.8 +/- 0.4 mug/100 ml (SEM) (151.9 +/- 5.1 nmol/l), and serum thyrotrophin (TSH) 6.7+/-1.0 muU/ml. Variability was marked for both T4 and TSH. Remeasured in the same patients on the fifth day of life, the TSH level was 3.7 +/- 1.0 muU/ml, lower than at birth (P less than 0.001), while scattering of TSH values was much smaller, with 99.4 % of values less than 12 muU/ml...
D003409:Congenital Hypothyroidism; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000175:diagnosis; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood
D013972:Thyrotropin; D013974:Thyroxine