Renal insufficiency and fosfomycin.
After the parenteral injection of 1 g sodium salt of fosfomycin the serum levels of the antibiotic are detected in a series of eight adult patients with different degrees of chronic renal insufficiencies four of them submitted to periodical dialysis. The results obtained reveal that the levels as well as the time of elimination of fosfomycin maintain an obvious relation to the degree of renal insufficiency in the patients.
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000097:blood*; D005578:Fosfomycin / Q000008:administration & dosage / Q000097:blood*; D006801:Humans; D007273:Injections, Intramuscular; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000628:therapy; D008875:Middle Aged; D006435:Renal Dialysis; D013997:Time Factors
D000900:Anti-Bacterial Agents; D005578:Fosfomycin