[Acute benign erythroblastopenia with normochromic anemia in childhood (author's transl)].
Two boys with acute benign erythroblastopenia are described. In contrast to patients with Gasser syndrome our two boys showed a severe normochromic anemia. Furthermore, no giant proerythroblasts were detectable in their bone marrow. A blockage of differentiation from hematopoietic stem cells to proerythroblasts is possibly the cause of the disease. A special therapy, besides transfusion of packed red cells if necessary, is not required.
D000741:Anemia, Aplastic / Q000097:blood* / Q000175:diagnosis / Q000628:therapy; D001803:Blood Transfusion; D001854:Bone Marrow Cells; D002675:Child, Preschool; D004900:Erythroblasts; D004912:Erythrocytes; D004920:Erythropoiesis; D006412:Hematopoietic Stem Cells; D006801:Humans; D008297:Male; D013577:Syndrome
Die akute benigne Erythroblastopenie mit normochromer Anämie, eine nicht seltene Erkrankung im Kleinkindesalter