title: Serum calcitonin and blood mineral interrelationships in normal children aged six to twelve years.
abstract: Simultaneous measurements of serum immunoreactive thyrocalcitonin (iTCT), immunoreactive parathyroid hormone (iPTH), calcium, inorganic phosphate, magnesium, and alkaline phosphatase were made in 37 normal children whose ages ranged from 6-12 years. Between the ages of 6 and 12 there is a statistically significant rise in serum iTCT levels (r = 0.4638; P less than 0.01), and a fall in serum iPTH levels (r = 0.4976; P less than 0.01). There is a highly significant inverse correlation between serum iTCT and iPTH levels (r = 0.5248; P less than 0.005). Serum iTCT levels were inversely correlated with phosphate levels (r = 0.4989; P less than 0.01), the latter being age dependent and falling significantly between the ages of 6 and 12 (r = 0.4802; P less than 0.001). There was no significant relationship between serum calcium levels and iTCT, iPTH, or age. Serum magnesium levels were not correlated with calcium, iTCT, or iPTH levels.
mesh_terms: D000328:Adult; D000367:Age Factors; D000469:Alkaline Phosphatase / Q000097:blood*; D000941:Antigens / Q000032:analysis; D002116:Calcitonin / Q000097:blood* / Q000276:immunology; D002118:Calcium / Q000097:blood*; D002648:Child; D002657:Child Development; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood; D007585:Jews; D008274:Magnesium / Q000097:blood*; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood* / Q000276:immunology; D010710:Phosphates / Q000097:blood*
chemical_list: D000941:Antigens; D006887:Hydroxycholecalciferols; D010281:Parathyroid Hormone; D010710:Phosphates; D002116:Calcitonin; D000469:Alkaline Phosphatase; D008274:Magnesium; D002118:Calcium