title: Antibiotic egg injection to eliminate disease. I. Effect of injection methods on turkey hatchability and Mycoplasma meleagridis infection.
abstract: Mycoplasma meleagridis infection in turkey hatching eggs was eliminated by injecting eggs with a combination of tylosin and gentamicin. Hatched F1 and F2 progeny remained free of egg-transmitted infection. Contact exposure was experienced in one negative flock. Of the preincubation injection procedures studied, a drilled hole on the small end of the egg was the inoculation site easiest to administer and best tolerated by the embryo. The embryo can tolerate a dose of gentamicin sulfate injected at 10 days of incubation that would be toxic if administered before incubation. Requirements for maintaining progeny free of infection are discussed.
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D004531:Eggs; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage* / Q000627:therapeutic use; D007185:Incubators; D007267:Injections; D007933:Leucomycins / Q000008:administration & dosage* / Q000627:therapeutic use; D008722:Methods; D009175:Mycoplasma Infections / Q000517:prevention & control / Q000662:veterinary*; D011201:Poultry Diseases / Q000517:prevention & control*; D014422:Turkeys / Q000254:growth & development / Q000502:physiology*
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins; D007933:Leucomycins