On the influence of Ca-DTPA on delta-aminolevulinic acid dehydratase in rats.
In rats red cell delta-aminolevulinic acid dehydratase is inhibited by Ca-DTPA only after treatment with toxic doses or with fractionated therapeutic doses. Zn-DTPA does not influence the activity of the enzyme even after administration of high doses.
D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D004912:Erythrocytes / Q000187:drug effects / Q000201:enzymology; D006836:Hydro-Lyases / Q000378:metabolism*; D008297:Male; D004369:Pentetic Acid / Q000494:pharmacology*; D000623:Porphobilinogen Synthase / Q000378:metabolism*; D051381:Rats; D015032:Zinc / Q000494:pharmacology
D004369:Pentetic Acid; D006836:Hydro-Lyases; D000623:Porphobilinogen Synthase; D015032:Zinc; D002118:Calcium