Platelet serotonin concentration and monoamine oxidase activity in unmedicated chronic schizophrenic and in schizoaffective patients.
Elevated blood serotonin, perhaps secondary to reduced platelet MAO, has been reported in a group of chronic schizophrenic patients. We have failed to find elevated platelet serotonin, or any relationship between platelet serotonin and MAO either in a group of unmedicated chronic schizophrenic patients or in a group of schizoaffective patients. Possible reasons for these discrepancies are discussed.
D000328:Adult; D000342:Affective Symptoms / Q000097:blood*; D000368:Aged; D001792:Blood Platelets / Q000201:enzymology / Q000378:metabolism*; D002908:Chronic Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000097:blood*; D012075:Remission, Spontaneous; D012559:Schizophrenia / Q000097:blood* / Q000188:drug therapy / Q000378:metabolism; D012701:Serotonin / Q000097:blood*
D012701:Serotonin; D008995:Monoamine Oxidase