[Glycine-14C and methionine-35S incorporation into liver and gastric mucosa proteins during sperm oil treatment of experimental stomach ulcer].
The effect of a course-wise introduction of the sperm oil on the intensity of the proteinic synthesis in experimental gastric ulcer was investigated. Tests were conducted on albino male-rats in which an experimental gastric ulcer failing to heal for a long time had been induced through introduction of a 5% acetic acid solution into the subserous membrane of the stomach. The intensity of the proteinic synthesis in the liver and gastric mucosa was assessed by the rate of the glycine-14C and methionine-35S incorporation in the total, mitochondrial and nucleonic proteins on the 7th, 14th, 21st and 28th days of the experimental ulcer course. The sperm oil secured a more effective production and thereby created propicious conditions for an intensified proteinic synthesis. It also contributed to an earlier normalization of the proteinic synthesis rates and to  a quicker cicatrization of the ulcerous defect.
D000818:Animals; D005753:Gastric Mucosa / Q000378:metabolism* / Q000648:ultrastructure; D005998:Glycine / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008297:Male; D008715:Methionine / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism; D008930:Mitochondria, Liver / Q000378:metabolism; D009821:Oils / Q000302:isolation & purification / Q000627:therapeutic use*; D014176:Protein Biosynthesis; D051381:Rats; D013276:Stomach Ulcer / Q000378:metabolism / Q000628:therapy*; D014907:Whales
D009821:Oils; D008715:Methionine; D005998:Glycine
Vkliuchenie glitsina-14C i metionina-35S v belki kletov pecheni i slizistoĭ zheludka pri lechenii spermatsetovym maslom iazvennykh porazheniĭ zheludka v ĕksperimente