title: [On spinal anaesthesia with isobaric bupivacaine 0,5% (author's transl)].
abstract: Clinical experiences of 5001 subarachnoid blocks using isobaric bupivacaine 0.5%, with and without adrenaline, for surgery are reported. The clinical results are satisfactory and no neurological sequelae are known to the authors. In vivo studies of C.S.F. after subarachnoid injection of bupivacaine 0.5% in an isobaric solution showed no changes in pH or precipitation. According to these results the authors see no contraindication in the use of bupivacine 0,5% for subarachnoid injection. The use of higher concentrations (e.g. 1%), however, can not be recommended.
mesh_terms: D000775:Anesthesia, Spinal; D002045:Bupivacaine / Q000134:cerebrospinal fluid; D004305:Dose-Response Relationship, Drug; D004837:Epinephrine; D006801:Humans; D013997:Time Factors
chemical_list: D002045:Bupivacaine; D004837:Epinephrine
vernacular_title: Zur Frage der Spinalanaesthesie mit isobarem Bupivacain 0,5%