title: Antimicrobial effect of amniotic fluid against anaerobic bacteria.
abstract: Amniotic fluid samples were obtained at term and tested for their antimicrobial effect on anaerobes, Peptostreptococcus (Ps.) anaerobius, Peptococcus (Pc.) prevotii, Bacteroides (B.) fragilis, and B. coagulans with facultative Escherichia (E.) coli serving as control. Amniotic fluid had only temporary bacteriostatic effect on Pc. prevotii and B. fragilis for 8 to 16 hours. This effect lasted for only 8 hours on Ps. anaerobius. On the contrary, the bacteriostatic effect of amniotic fluid was well sustained on E. coli and B. coagulans, lasting for the entire test periods of 20 and 32 hours, respectively. At the end of the time intervals mentioned, Ps. anaerobius, Pc. prevotii, and B. fragilis exhibited logarithmic growth, confirming the earlier reports that it is not nutritionally deficient. Amniotic fluid exhibited temporary bacteriostatic effect on Ps. anaerobius, P. prevotii, and B. fragilis, but this effect was well sustained against B. coagulans.
mesh_terms: D000653:Amniotic Fluid; D001419:Bacteria / Q000254:growth & development*; D001439:Bacteroides / Q000254:growth & development; D001441:Bacteroides fragilis / Q000254:growth & development; D005260:Female; D006801:Humans; D010460:Peptococcus / Q000254:growth & development; D010462:Peptostreptococcus / Q000254:growth & development; D011247:Pregnancy