Demonstration of a depressor reflex in acute cardiac tamponade.
Studies from our laboratory have demonstrated the presence of a vagally mediated reflex in acute cardiac tamponade. To determine the effect of thisreflex on cardiac performance, we continuously recorded hemodynamic parameters during induction  of tamponade in 16 closed-chest mongrel dogs anesthetized with alpha chloralose. The studies were done 1 to 7 days following the insertion of a catheter in the pericardial sac. With increasing pericardial volume, there was a progressive deterioration of cardiac performance, the most marked changes occuring in the late phases of cardiac tamponade...
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001919:Bradycardia / Q000503:physiopathology; D006328:Cardiac Catheterization; D002305:Cardiac Tamponade / Q000503:physiopathology*; D004195:Disease Models, Animal; D004285:Dogs; D004562:Electrocardiography; D006321:Heart / Q000294:innervation / Q000503:physiopathology*; D006439:Hemodynamics / Q000187:drug effects; D010490:Pericardial Effusion / Q000503:physiopathology; D012018:Reflex; D014630:Vagus Nerve
D001285:Atropine