Metallothionein synthesis as an indication of the parenchymal origin of cells cultured from liver.
A line of cell derived from pig liver has been shown to retain the ability to synthesize zinc-thionein and to respond to Cd2+ with a greatly increased metallothionein synthesis, a property specific for liver and kidney parenchymal cells.
D000818:Animals; D002104:Cadmium / Q000378:metabolism; D002478:Cells, Cultured; D066298:In Vitro Techniques; D008099:Liver / Q000166:cytology* / Q000378:metabolism; D008667:Metalloproteins / Q000096:biosynthesis*; D008668:Metallothionein / Q000096:biosynthesis*; D011868:Radioisotopes; D013552:Swine
D008667:Metalloproteins; D011868:Radioisotopes; D002104:Cadmium; D008668:Metallothionein