title: Abdominal pain in donors during filtration leukapheresis.
abstract: An unusual donor reaction characterized primarily by lower abdominal and/or perineal pain occurs in 1.2 per cent of donors during filtration leukapheresis (FL). The reaction occurs almost exclusively in female donors. Corticosteroid pretreatment appears to be highly effective in preventing the reaction. The pathogenesis of this donor problem is speculative.
mesh_terms: D000005:Abdomen; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D005260:Female; D006801:Humans; D017708:Leukocyte Transfusion; D008875:Middle Aged; D010146:Pain / Q000209:etiology* / Q000517:prevention & control; D065227:Transfusion Reaction
chemical_list: D000305:Adrenal Cortex Hormones