title: [State of hematopoiesis during irradiation simulating radiation exposure in prolonged space flight].
abstract: The paper presents the results of studies of the peripheral blood and bone marrow of 36 male dogs exposed to a chronic 3 year gamma-irradiation (from the Co60 source) at a dose rate of 0.17 rad per day which was combined with acute irradiations. The animals received two doses -360 and 564 rad in total. The leukoblastic system showed inhibition and decreased reactivity in case of irradiation with a higher dose. The red blood cell balance remained stable for a long period of time due to activated erythropoiesis.
mesh_terms: D000818:Animals; D001772:Blood Cell Count; D001773:Blood Cells / Q000528:radiation effects; D001853:Bone Marrow / Q000528:radiation effects; D001854:Bone Marrow Cells; D003037:Cobalt Radioisotopes; D004285:Dogs; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006410:Hematopoiesis / Q000528:radiation effects*; D008297:Male; D011829:Radiation Dosage; D013026:Space Flight; D013997:Time Factors
chemical_list: D003037:Cobalt Radioisotopes
vernacular_title: Sostoianie krovetvoreniia pri obluchenii, imitiruiushchem radiatsionnoe vozdeĭstvie v usloviiakh dlitel'nogo kosmicheskogo poleta