Use of dexamethasone in treatment of insulin lipoatrophy.
To treat insulin lipoatrophy, small amounts of dexamethasone (4 micrograms/unit) were added to insulin injections in nine patients. Six cases showed significant improvement of dexamethasone-treated sites over that of control sites in six months. With the continued use of dexamethasone-containing insulin, they remained mostly free of atrophic areas during the follow-up period of over two years. Our experience suggests the usefulness of this therapy.
D000273:Adipose Tissue / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D001284:Atrophy / Q000188:drug therapy; D003907:Dexamethasone / Q000627:therapeutic use*; D003920:Diabetes Mellitus / Q000188:drug therapy; D005260:Female; D006801:Humans; D007328:Insulin / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged
D007328:Insulin; D003907:Dexamethasone