Hypomelanotic canopy of sarcoidosis.
A case of cutaneous hypopigmented macules localized above deep dermal and subcutaneous sarcoid granulomas in a patient with systemic sarcoidosis is presented. Melanin was only sparsely distributed in the upper stratum malpighii. Hypopigmentation is an unusual manifestation of sarcoidosis. With an armamentarium of clinical observation, dermatologists may suspect a hypomelanotic cutaneous diadem overlying a palpable dermal mass to be a visual vignette of a sarcoidal montage requiring diagnostic biopsy.
D000328:Adult; D005260:Female; D006099:Granuloma / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D010859:Pigmentation Disorders / Q000473:pathology*; D012507:Sarcoidosis / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012880:Skin Pigmentation