title: [The effect of filtering operations (author's transl)].
abstract: The effect of filtering operations on 133 eyes was investigated by fluorescence photography after intracameral injection of fluorescein. The following drainage mechanisms could be found: 1. the transconjunctival route, 2. the diffuse resorption through degenerated veins, 3. bulkflow through lymphatic vessels, 4. bulkflow through atypic aqueous veins, 5. outflow through normal aqueous veins. A filtering bleb develops, if the transconjunctival route and the diffuse resorption is predominent. Newly incorporated veins and lymphatic vessels enable the drainage of the aqueous humour without a visible bleb. Most important for the formation of these vessels is the surgical technique. Therefore it is not only necessary to cover the fistula with a scleral flap but also to gain a physiological intraocular pressure immediately after the operation. If the tension is too low in most cases a filtering bleb will form. If it is at a physiological level (i.c. above the episcleral vein pressure) new vessels can develop and drain the aqueous humour by bulkflow from the scleral fistula and that means a good pressure regulating effect without a filtering bleb.
mesh_terms: D001082:Aqueous Humor / Q000502:physiology*; D003228:Conjunctiva / Q000502:physiology; D005123:Eye / Q000098:blood supply; D005452:Fluoresceins; D005901:Glaucoma / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D007700:Kinetics; D008208:Lymphatic System / Q000502:physiology; D014129:Trabecular Meshwork / Q000601:surgery*; D014680:Veins
chemical_list: D005452:Fluoresceins
vernacular_title: Zur Wirkungsweise fistelbildender Operationen