Human somatomedin A and longitudinal bone growth in the hypophysectomized rat.
A somatomedin A preparation, when given at total doses of 14 and 70 U did not increase the longitudinal bone growth in hypophysectomized rats. Growth hormone (WHO) significantly increased the longitudinal bone growth.
D000818:Animals; D001681:Biological Assay; D001835:Body Weight / Q000187:drug effects; D001846:Bone Development / Q000187:drug effects*; D001842:Bone and Bones / Q000187:drug effects; D002356:Cartilage / Q000187:drug effects / Q000254:growth & development; D005260:Female; D013006:Growth Hormone / Q000494:pharmacology; D007016:Hypophysectomy; D051381:Rats; D013002:Somatomedins / Q000494:pharmacology*; D013974:Thyroxine / Q000494:pharmacology
D013002:Somatomedins; D013006:Growth Hormone; D013974:Thyroxine