title: Effect of drugs which alter microsomal drug-metabolizing enzyme activity on rat hepatic cholesterol biosynthesis.
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000096:biosynthesis*; D003035:Cobalt / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003897:Desmosterol / Q000096:biosynthesis; D006903:Hydroxymethylglutaryl CoA Reductases / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008797:Metyrapone / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D009570:Nitriles / Q000494:pharmacology; D010634:Phenobarbital / Q000494:pharmacology*; D010882:Piperonyl Butoxide / Q000494:pharmacology*; D011284:Pregnenolone / Q000494:pharmacology*; D051381:Rats; D013261:Sterols / Q000096:biosynthesis
chemical_list: D009570:Nitriles; D013261:Sterols; D003897:Desmosterol; D003035:Cobalt; D011284:Pregnenolone; D003577:Cytochrome P-450 Enzyme System; D002784:Cholesterol; D006903:Hydroxymethylglutaryl CoA Reductases; D010882:Piperonyl Butoxide; D010634:Phenobarbital; D008797:Metyrapone