Effect of radiation therapy on facial nerve cable autografts.
Facial nerve cable autografts were performed on 20 cats with 10 animals receiving 6,000 Rads of postoperative irradiation over six weeks. Testing by clinical appearance, pontograms, and axon counts showed no statistical difference in the operated only and the operated plus irradiated groups. Pontograms illustrated the clinical observance of spasticity, delay and weakness often seen after grafting. This animal work tends to verify the clinical impression that in patients requiring postoperative irradiation for a malignancy necessitating excision and grafting of the facial nerve, anticipated results should be equivalent to the facial nerve cable autografts without postoperative irradiation.
D000818:Animals; D002415:Cats; D004195:Disease Models, Animal; D005154:Facial Nerve / Q000473:pathology / Q000528:radiation effects / Q000637:transplantation*; D006085:Graft Survival / Q000528:radiation effects*; D011879:Radiotherapy Dosage; D014182:Transplantation, Autologous