Zero-order drug delivery system: theory and preliminary testing.
A new approach to zero-order drug delivery that includes geometric factors is described. An experimental device based on the theory was tested by following the release of stearic acid into ethanol. Three separate trials indicated that the solid was released via a zero-order process in a reproducible manner.
D003692:Delayed-Action Preparations; D004058:Diffusion; D004343:Drug Implants; D008433:Mathematics; D008722:Methods; D008962:Models, Theoretical; D011108:Polymers; D012995:Solubility; D013229:Stearic Acids; D013499:Surface Properties; D013535:Suspensions; D013997:Time Factors
D003692:Delayed-Action Preparations; D004343:Drug Implants; D011108:Polymers; D013229:Stearic Acids; D013535:Suspensions