Studies on the Pelger anomaly in Iceland.
An Icelandic family, containing 15 members with Pelger anomally, is reported. Affected individuals in two branches of the family, living in the south-east and east of Iceland, have been traced to common ancestors born 200 years age. The results of scanning of blood films from approximately 20% of the population of Iceland suggest that the Pelger family described contains the only mutation of this kind in Icelanders.
D005260:Female; D006801:Humans; D007055:Iceland; D008297:Male; D008403:Mass Screening; D010375:Pedigree; D010381:Pelger-Huet Anomaly / Q000453:epidemiology / Q000235:genetics*