Avascular transplantation of small bowel in newborn piglets.
Segments of small bowel of newborn piglets were isolated and wrapped in omentum as free autotransplants. After initial necrosis, they regenerate either completely, or at least their muscular layer is restored. As there is a lot of inflammatory reaction in most of the grafts, the conclusion is drawn that either preexisting infection, or autoaggressive reactions are responsible for this. Homografts behave like autografts in the beginning, their structures being restored, but are all rejected by the sixth week. Immaturity of the immunologic system in the newborn may be the reason for this late rejection.
D000818:Animals; D000831:Animals, Newborn; D007421:Intestine, Small / Q000473:pathology / Q000637:transplantation*; D013552:Swine; D013997:Time Factors; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous