Mass spectrometry of cyclopenta[alpha]phenanthrenes. Metabolites formed in vitro and in vivo from the carcinogen 15,16-dihydro-11-methyl-cyclopenta[alpha]phenanthren-17-one.
The mass spectra of a number of synthetic cyclopenta[alpha]phenanthrenes are described, and identification of an in vitro metabolite of a carcinogen of this series is reported. The correlation of the mass spectra of the major urinary metabolite, its dehydration product and its triacetate with the structure assigned to the metabolite is described.
D000818:Animals; D002273:Carcinogens / Q000378:metabolism; D006067:Gonanes / Q000032:analysis* / Q000378:metabolism; D007664:Ketosteroids / Q000378:metabolism; D013058:Mass Spectrometry; D051381:Rats
D002273:Carcinogens; D006067:Gonanes; D007664:Ketosteroids