[Adrenosensitive neurons of the myenteric (Auerbach's) plexus].
Experiments were conducted on the myenteral plexus of the isolated stips of the small and large intestine; the presence of adrenosensitive cells which reacted to the application of different adrenaline (A) and noradrenaline (NA) concentrations by a distinct acceleration of the activity rhythm was demonstrated. NA with a greater range of action than A (from 10(-9) to 10(-5 g/ml) has the most marked effect. Introduction into the irrigating solution of phentholamine eliminated the mentioned effects in the majority of cases. "Silent" neurons without any spontaneous activity responded to the A and NA administration along with those possessing this activiy. As supposed, catecholamines could take a direct part in the modulation of the processes realized by the ganglionic neurons of the myenteral plexus.
D000818:Animals; D002415:Cats; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004594:Electrophysiology; D004837:Epinephrine / Q000494:pharmacology*; D007420:Intestine, Large / Q000294:innervation; D007421:Intestine, Small / Q000294:innervation; D009197:Myenteric Plexus / Q000187:drug effects*; D009638:Norepinephrine / Q000494:pharmacology*; D010646:Phentolamine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology
D011433:Propranolol; D009638:Norepinephrine; D004837:Epinephrine; D010646:Phentolamine
Adrenochuvstvitel'nye neĭrony miénteral'nogo (Auérbakhova) spleteniia