The shaking patient. Diagnosis and management of tremor.
Tremor can be categorized into three general types: resting, action, and intention, Each requires different therapy. Resting tremor is present when the hands are at rest; it disappears with movement. It is characteristic of Parkinson's disease and responds to treatment with L-dopa either alone or in combination with a decarboxylase inhibitor. Action tremor is maximal when the hands are outstretched to the front; it may persist during movement. It is not rare and is often misread as a sign of Parkinson's disease. Propranolol is beneficial. Intention tremor occurs with movement and is characteristic of cerebellar disease. Pharmacologic agents are not helpful. The only known effective treatment is stereotaxic surgery.
D000547:Amantadine / Q000627:therapeutic use; D002230:Carbidopa / Q000627:therapeutic use; D002526:Cerebellar Diseases / Q000150:complications / Q000601:surgery; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D010300:Parkinson Disease / Q000150:complications / Q000188:drug therapy; D011433:Propranolol / Q000627:therapeutic use; D014202:Tremor / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology
D007980:Levodopa; D011433:Propranolol; D000547:Amantadine; D002230:Carbidopa