Normal sugar uptake in vitro by small-bowel biopsies from a patient with cholera.
We have investigated the 3-O-methyl-D-glucose (3MG) absorption by jejunal biopsies obtained from a patient with cholera. The absorption of 3MG (as measured from the determination of intracellular accumulation of this sugar) was found to occur against a concentration gradient and to be a saturable process that follows Michaelis-Menten kinetics. There was no appreciable difference in 3MG absorption between the biopsies from the normal volunteers and those from the patient with cholera.
D000328:Adult; D002771:Cholera / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007410:Intestinal Diseases / Q000378:metabolism; D007583:Jejunum / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D008757:Methylglucosides / Q000378:metabolism*; D008759:Methylglycosides / Q000378:metabolism*
D008757:Methylglucosides; D008759:Methylglycosides