title: Effects of ibotenic acid, quisqualic acid and their relatives on the excitability of an identifiable giant neurone of an African giant snail (Achatina fulica Férussac).
abstract: An identifiable giant neurone, PON (periodically oscillating neurone), of Achatina fulica Ferussac, inhibited by erythro-beta-hydroxy-L-glutamic acid, was also inhibited by 2 relatives of beta-hydroxy glutamic acid, ibotenic acid and quisqualic acid. These substances similarly showed the effect on the neurone even in the chloride-free medium.
mesh_terms: D000409:Alanine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D005971:Glutamates / Q000494:pharmacology*; D007051:Ibotenic Acid / Q000494:pharmacology*; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D010069:Oxadiazoles / Q000494:pharmacology*; D010080:Oxazoles / Q000494:pharmacology*; D012908:Snails / Q000502:physiology*; D013329:Structure-Activity Relationship
chemical_list: D005971:Glutamates; D010069:Oxadiazoles; D010080:Oxazoles; D007051:Ibotenic Acid; D000409:Alanine