[Effect of heparin on enzyme processes in the myocardium and liver of animals of different ages].
Experiments conducted with albino mice and male-rats of different age have brought evidence that heparin is capable of raising the resistance of the organism to hypoxic hypoxia, stimulating the activity of NAD-dependent and inhibiting that of flavine-dependent dehydrogenases in the liver and myocardium of rats. It also inhibits peroxidation of lipids and the activity of lyzosomal enzymes in the liver, particularly in old animals. The expediency of a course-wise application of heparin, especially in old age, is suggested.
D000367:Age Factors; D000818:Animals; D006493:Heparin / Q000494:pharmacology*; D008099:Liver / Q000201:enzymology*; D008297:Male; D008928:Mitochondria / Q000201:enzymology; D008930:Mitochondria, Liver / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology* / Q000648:ultrastructure; D010088:Oxidoreductases / Q000378:metabolism*; D051381:Rats
D006493:Heparin; D010088:Oxidoreductases
Vliianie geparina na fermentativnye protsessy miokarda i pecheni zhivotnykh raznogo vozrasta