Hepatic adenomas and focal nodular hyperplasia of the liver in young women on oral contraceptives: case reports.
Two cases of hepatic adenoma and one of focal nodular hyperplasia presumably associated with the use of oral contraceptives, are reported. Special reference is made to their clinical presentation, which may be totally asymptomatic. Liver-function tests are of little diagnostic value, but valuable information may be obtained from both liver scanning and hepatic angiography. Histologic differences and clinical similarities between hepatic adenoma and focal nodular hyperplasia of the liver are discussed.
D000236:Adenoma / Q000139:chemically induced* / Q000175:diagnosis / Q000000981:diagnostic imaging; D000328:Adult; D000792:Angiography; D056486:Chemical and Drug Induced Liver Injury; D003276:Contraceptives, Oral / Q000009:adverse effects*; D003280:Contraceptives, Oral, Synthetic / Q000009:adverse effects*; D004338:Drug Combinations; D045166:Estradiol Congeners / Q000009:adverse effects; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000000981:diagnostic imaging; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000175:diagnosis; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000175:diagnosis / Q000000981:diagnostic imaging; D008656:Mestranol / Q000009:adverse effects; D009641:Norethynodrel / Q000009:adverse effects; D011247:Pregnancy; D045167:Progesterone Congeners / Q000009:adverse effects; D011877:Radionuclide Imaging
D003276:Contraceptives, Oral; D003280:Contraceptives, Oral, Synthetic; D004338:Drug Combinations; D045166:Estradiol Congeners; D045167:Progesterone Congeners; D009641:Norethynodrel; D008656:Mestranol