Production of aflatoxicol from aflatoxin B1 by postmitochondrial liver fractions.
Fish liver postmitochondrial supernatant preparations in the presence of carbon monoxide were used to prepare purified aflatoxicol from aflatoxin B1 in high yield (23-38%). Such fish liver postmitochondrial and postmicrosomal supernatant preparations were five to ten times more active in making aflatoxicol than rat or human liver preparations under the same conditions.
D000328:Adult; D000348:Aflatoxins / Q000378:metabolism*; D000818:Animals; D002248:Carbon Monoxide / Q000494:pharmacology; D005260:Female; D005399:Fishes / Q000378:metabolism; D006801:Humans; D008099:Liver / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged; D051381:Rats; D013045:Species Specificity; D013347:Subcellular Fractions / Q000187:drug effects / Q000378:metabolism*; D013997:Time Factors; D014337:Trout / Q000378:metabolism
D000348:Aflatoxins; D002248:Carbon Monoxide