title: Studies in ureteral regeneration: replacement of a large segment of ureter with an in situ pedicle graft of proximal ureter.
abstract: The phenomenon of ureteral regeneration has been of interest to clinicians, anatomists, and physiologists for many years. The object of this investigation was to study the regeneration of a long pedicle graft of ureter. Regeneration of the pedicle graft over a stent took place in 4 to 5 weeks. At sacrifice 8 to 10 months postoperatively, 7 of 10 operations were completely successful with no evidence of hydronephrosis, obstruction, or pyelonephritis. Two animals exhibited slight dilation of the upper tracts, and one operation was a failure. It is evident from this study that a strip of ureter removed from the ureteral artery will regenerate over a stent in 4 to 5 weeks if the blood supply from the adjacent adventitia is left intact.
mesh_terms: D000818:Animals; D004285:Dogs; D006869:Hydronephrosis; D012038:Regeneration; D014182:Transplantation, Autologous; D014513:Ureter / Q000502:physiology* / Q000637:transplantation