title: Computed tomographic appearance of methotrexate-induced necrotizing leukoencephalopathy.
abstract: A case of methotrexate-induced brain damage is presented. Computed tomography (CT) demonstrated a high-density mass lesion with a low-density area in the white matter which pathologically represented a large area of acute necrotizing cerebritis. CT appearance was indistinguishable from brain abscess.
mesh_terms: D000328:Adult; D001922:Brain Abscess / Q000000981:diagnostic imaging; D001927:Brain Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects*; D009336:Necrosis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
chemical_list: D008727:Methotrexate