title: Dietary requirements of subjects exposed to hyperbaric He-O2 conditions: effects of various levels of vitamin supplementation.
abstract: A 24-d growth study was conducted on rats exposed to ambient air, 11 ATA He-O2, or 21 ATA  He-O2 conditions. The rats were fed either a standard diet or the standard diet supplemented with 25, 50, or 100% increase of all vitamins, or the last with an additional 50 or 100% increase of casein. Fat, as cod liver oil was increased 0.5, 1.0, or 2.0% of the diet as the vitamins were increased. The vitamin and fat-supplemented diets, with or without supplemental casein, were adequate to support normal growth of the rats exposed to 11 ATA but not 21 ATA He-O2 conditions. Urine excretion and water consumption were closely related and varied in accordance with the adequacy of the diet. Feed digestibility was not a limiting factor in determining the growth of the rats under the three environments. The composition of the rat carcasses varied minimally.
mesh_terms: D000818:Animals; D001274:Atmospheric Pressure; D001823:Body Composition; D001835:Body Weight; D002364:Caseins / Q000378:metabolism; D004041:Dietary Fats; D006128:Growth; D006371:Helium; D008297:Male; D009747:Nutritional Physiological Phenomena; D009751:Nutritional Requirements; D010100:Oxygen; D051381:Rats; D014556:Urine; D014815:Vitamins / Q000378:metabolism*; D014867:Water
chemical_list: D002364:Caseins; D004041:Dietary Fats; D014815:Vitamins; D014867:Water; D006371:Helium; D010100:Oxygen