title: Phenothiazine-induced bulbar palsy-like syndrome and sudden death.
abstract: There have been periodic case reports of sudden death due to aspiration or asphyxiation in patients receiving phenothiazines. The mechanism of death is unknown. The author reports a case of a drug-induced bulbar palsy-like syndrome in a man receiving fluphenazine enanthate and reviews the literature on sudden respiratory death and phenothiazines. He postulates that phenothiazine-induced bulbar palsy may cause laryngeal and/or pharyngeal dysfunctions that are responsible for aspiration.
mesh_terms: D001237:Asphyxia / Q000139:chemically induced; D010244:Bulbar Palsy, Progressive / Q000139:chemically induced*; D003645:Death, Sudden; D005476:Fluphenazine / Q000008:administration & dosage / Q000009:adverse effects*; D005683:Gagging / Q000187:drug effects; D006801:Humans; D001239:Inhalation; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D010259:Paranoid Disorders / Q000188:drug therapy
chemical_list: D005476:Fluphenazine