Effect of potassium on utilization of (1-14C)palmitic acid in renal cortex of the rat.
The renal cortex has an unusually high rate of palmitic acid utilization. The uptake, oxidation, and distribution of this fatty acid in the cortex, unlike other tissues, responds to variations in medium and tissue potassium content. This potassium dependency is mimicked and amplified by rubidium. These observations indicate that in the renal cortex, both potassium and rubidium promote the accumulation, oxidation, and esterification of palmitic acid.
D000818:Animals; D005227:Fatty Acids / Q000378:metabolism; D005260:Female; D007672:Kidney Cortex / Q000187:drug effects / Q000378:metabolism*; D010084:Oxidation-Reduction / Q000187:drug effects; D010100:Oxygen; D010169:Palmitic Acids / Q000378:metabolism*; D010313:Partial Pressure; D011188:Potassium / Q000494:pharmacology*; D011189:Potassium Chloride / Q000494:pharmacology; D051381:Rats; D012413:Rubidium / Q000494:pharmacology
D005227:Fatty Acids; D010169:Palmitic Acids; D011189:Potassium Chloride; D012413:Rubidium; D011188:Potassium; D010100:Oxygen