[Relationship between concentration and the character of the effect of adrenaline on the excitatibility of giant neurons].
The nature of the epinephrine action on the excitability of giant neurons depends on its concentration. With a concentration of 1-10(-5) M changes in electrophysiological parameters of the somatic neurons membrane produced by its bore proof to the rising and with that of 1-10(-4) M -- to its falling excitability. Propranolol was indifferent in regard to both epinephrine effects, while dihydroergotoxin abolished the inhibitory effect of epinephrine.
D000818:Animals; D004088:Dihydroergotoxine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004837:Epinephrine / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D005724:Ganglia / Q000187:drug effects*; D008195:Lymnaea; D008564:Membrane Potentials / Q000187:drug effects*
D004088:Dihydroergotoxine; D004837:Epinephrine
Kontsentratsionnaia zavisimost' kharaktera vliianiia adrenalina na vozbudimost' gigantskikh neĭronov