Evaluation of biodegradable ceramic.
An evaluation of a porous biodegradable ceramic, tricalcium phosphate, has been carried out. When implanted in cancellous bone, it is rapidly infiltrated with bone and slowly resorbed. When held rigidly against raw, bleeding, cortical bone, again rapid bone ingrowth occurs. The material does not give rise to any untoward tissue reaction, nor does it cause any systemic reaction. It can therefore be concluded that the material is safe for use in clinical practice, and can be used in specific instances either to replace or to supplement bone grafting.
D000818:Animals; D001672:Biocompatible Materials; D001673:Biodegradation, Environmental; D001696:Biomechanical Phenomena; D001846:Bone Development; D001842:Bone and Bones / Q000033:anatomy & histology / Q000187:drug effects; D002130:Calcium Phosphates / Q000494:pharmacology*; D002516:Ceramics; D004285:Dogs; D005069:Evaluation Studies as Topic; D013997:Time Factors
D001672:Biocompatible Materials; D002130:Calcium Phosphates