Mechanisms and prevention of cancer dissemination: an overview.
Synthesizing data from many experimental and clinical courses, a current working model for tumor dissemination has been constructed. Several aspects of this model are being exploited to therapeutic advantage for the patient with cancer. Surgeons should continue to exercise the principles of en bloc tumor resection and employ maneuvers to minimize iatrogenic tumor dissemination .
D000818:Animals; D000925:Anticoagulants / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002199:Capillary Permeability / Q000187:drug effects; D002448:Cell Adhesion / Q000187:drug effects; D002465:Cell Movement / Q000187:drug effects; D006801:Humans; D007111:Immunity, Cellular; D008207:Lymphatic Metastasis / Q000517:prevention & control; D008938:Mitosis / Q000187:drug effects; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis / Q000517:prevention & control*; D009366:Neoplasm Seeding; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000517:prevention & control; D009360:Neoplastic Cells, Circulating; D009928:Organ Specificity; D011879:Radiotherapy Dosage; D013927:Thrombosis / Q000517:prevention & control
D000925:Anticoagulants; D000970:Antineoplastic Agents