Hereditary complement defect and kinins involvement in asthma.
Relationship between an inherited qualitative defect of the complement system and intrinsic asthma, and the direct participation of the kinin system in producing asthma, are reported. Qualitative complement impairment that produced hereditary angioedema in the son of an asthmatic father indicated that the kinin system was the vasoactive mediator in both cases.
D000293:Adolescent; D000799:Angioedema / Q000235:genetics*; D001249:Asthma / Q000209:etiology* / Q000378:metabolism; D001777:Blood Coagulation; D003165:Complement System Proteins / Q000172:deficiency*; D005342:Fibrinolysis; D006801:Humans; D007705:Kinins / Q000378:metabolism*; D008297:Male; D008875:Middle Aged
D007705:Kinins; D003165:Complement System Proteins