Use of microfibrillar collagen as a topical hemostatic agent in brain tissue.
Microfibrillar collagen, a recently introduced topical hemostatic agent, was used to obtain hemostasis in suction-evacuation lesions of canine cortex. Gelatin foam was used as a control in identical lesions on the opposite side. Microfibrillar collagen was found to be faster acting and more effective than gelatin foam. Histological evaluation of the lesions at 2,4, and 6 months postoperatively showed no significant difference in the amount or type of tissue reaction to the two agents.
D000818:Animals; D001921:Brain / Q000601:surgery*; D003094:Collagen / Q000627:therapeutic use*; D004285:Dogs; D005781:Gelatin Sponge, Absorbable; D006488:Hemostasis, Surgical / Q000379:methods*; D011183:Postoperative Complications
D003094:Collagen