title: Food intake controls in the suckling pig: glucoprivation and gastrointestinal factors.
abstract: The energy balance of suckling Yorkshire pigs 1 day to 2 wk old was challenged by: food deprivation, glucoprivation, and caloric and noncaloric gastric loads delivered by intubation. tafter 2--4 h fasts, food intake greatly increased over nonfasted control intake during a 3-h refeeding period. This response occurred both when body weight gain was used as a measure of intake for pigs nursing on the sow and when intake was measured directly in bottle-fed pigs. Glucoprivation produced by 0.5--2 U/kg insulin did not stimulate food intake although plasma glucose fell to a mean of 49 mg/100 ml (43% of control) after 1 U/kg insulin. Gastric loads of water or 3% NACl depressed intake after 3-h fast, but 0.9% NaCl did not. All the caloric gastric loads depressed intake; in order of increasing effectiveness, they were: heavy cream, protein hydrolysate, corn oil, milk, 5% glucose, and 5% lactose. The carbohydrate loads were most effective, a result which indicates that the response was not to calories alone but to some specific nutrient, possibly glucose.
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D001786:Blood Glucose / Q000378:metabolism; D004040:Dietary Carbohydrates / Q000378:metabolism; D002149:Energy Intake; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology*; D005260:Female; D005508:Food Deprivation; D007328:Insulin / Q000494:pharmacology; D008297:Male; D012462:Saline Solution, Hypertonic / Q000494:pharmacology; D013270:Stomach / Q000502:physiology; D013552:Swine / Q000502:physiology*; D014867:Water / Q000494:pharmacology
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D007328:Insulin; D012462:Saline Solution, Hypertonic; D014867:Water