The uptake and egress of adenine from human red blood cells in vitro.
The initial uptake of adenine from plasma by human red blood cells was measured at 0, 10, and 20 C. Initial uptake is completed in several minutes as distribution equilibrium is reached; however, total uptake requires several weeks at 4 C. Adenine inside the red blood cell was shown to egress to the plasma if the equilibrium shifted due to plasma dilution or exchange.
D000225:Adenine / Q000378:metabolism*; D000249:Adenosine Monophosphate / Q000378:metabolism; D001793:Blood Preservation; D003080:Cold Temperature; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D013997:Time Factors
D000249:Adenosine Monophosphate; D000225:Adenine