CNS regulation of salt and water intake.
The brain has evolved a number of mechanisms to maintain body fluid balance. They include the sensation of thirst, which stimulates water intake, the secretion of vasopressin, which helps prevent water loss, and the secretion of aldosterone, which helps prevent sodium depletion. In the research described here, all three mechanisms are shown to be mediated by the actions of angiotensin on the brain.
D000450:Aldosterone / Q000378:metabolism; D000804:Angiotensin II / Q000502:physiology; D000818:Animals; D001921:Brain / Q000502:physiology*; D003681:Dehydration / Q000503:physiopathology; D004285:Dogs; D004326:Drinking; D005110:Extracellular Space / Q000502:physiology; D006801:Humans; D007424:Intracellular Fluid / Q000502:physiology; D009994:Osmolar Concentration; D012083:Renin / Q000502:physiology; D012964:Sodium / Q000378:metabolism*; D013894:Thirst / Q000502:physiology; D014667:Vasopressins / Q000378:metabolism; D014882:Water-Electrolyte Balance
D014667:Vasopressins; D000804:Angiotensin II; D000450:Aldosterone; D012964:Sodium; D012083:Renin