Action of vasodilators on regional cerebral blood flow in subacute or chronic cerebral ischemia.
Regional cerebral blood flow (bicompartmental and stochastic method) was measured in a series of 20 patients with unilateral brain softening. Measurements were repeated during the administration of a vasodilator. A deterimental effect on the perfusion of the disease area was observed in the majority of cases. It has been shown that the chances for a vasodilator to decrease the perfusion in the diseased area were greater when the angiogram showed obstruction of an intracranial artery.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001921:Brain / Q000098:blood supply*; D002533:Cerebral Angiography; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D005260:Female; D006221:Halothane / Q000494:pharmacology; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000494:pharmacology; D011877:Radionuclide Imaging / Q000379:methods; D014665:Vasodilator Agents / Q000494:pharmacology*
D014665:Vasodilator Agents; D010208:Papaverine; D006221:Halothane