[Comparative blood flow measurements with arterio-venous oxygen difference and the 133-Xenon-technique in the region supplied by the left coronary artery (author's transl)].
In 17 mainly coronary patients increase in blood flow due to therapeutical vasodilation was measured in the region almost totally supplied by the left coronary artery by two different methods, the 133-Xenon washout technique and via arterio-venous oxygen difference (AVDO2). With both methods similar results were obtained (r=0.89). Mean maximal increase in flow 15 min. after 40 mg Carbochromen i.v. amounted to +22.4% with the 133-Xenontechnique, +21.5% with AVDO2. 5min. after 20 mg intracoronary dipyridamol mean flow increased by 47.8% (Xenon technique) and 47.1% (AVDO2) respectively. Decrease in coronary reserve is correlated more with the amount of damaged byocardium than with the degree of coronary obstruction. The limited reliablility of all measurements of total coronary blood flow in heart diseases with regional disturbances is specially indicated.
D000328:Adult; D001158:Arteries; D006328:Cardiac Catheterization; D003326:Coronary Circulation / Q000187:drug effects; D004176:Dipyridamole / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D014680:Veins; D014980:Xenon Radioisotopes
D014980:Xenon Radioisotopes; D004176:Dipyridamole; D010100:Oxygen
Vergleichende Durchblutungsmessung im Ausbreitungsgebiet der linken Kranzarterie mit der AVDO2-under der 133-Xenon-Technik