title: Note on comparison of small proportions in large-scale experiments.
abstract: A statistical confidence interval procedure was given for comparison of a treatment to a control where the response of each experimental unit was binary, e.g., presence or absence of a tumor. The method was appropriate when the two sample sizes were moderately large but the number of positive responses was small. The confidence interval was for the ratio of the two response rates.
mesh_terms: D006801:Humans; D009369:Neoplasms / Q000453:epidemiology*; D012107:Research Design; D012494:Sampling Studies; D013223:Statistics as Topic