title: Inhibition by PGE2 and by phenylephrine of catecholamine release from human adrenal in vitro.
abstract: The release of catecholamines from human adrenal was studied by in vitro incubation of slices. Catecholamine release was significantly inhibited by the addition of either phenylephrine (10(-5) M) or PGE2 (10(-7) M) to the incubation medium. The similarity of these modulating actions to those found in rat adrenal is discussed.
mesh_terms: D000293:Adolescent; D000311:Adrenal Glands / Q000378:metabolism*; D000328:Adult; D002395:Catecholamines / Q000378:metabolism*; D003864:Depression, Chemical; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D010656:Phenylephrine / Q000494:pharmacology*; D011458:Prostaglandins E / Q000494:pharmacology*
chemical_list: D002395:Catecholamines; D011458:Prostaglandins E; D010656:Phenylephrine