Joint resurfacing in the rabbit using an autologous osteochondral graft.
In rabbits, joint resurfacing with autologous osteoarticular condylar grafts composed of the articular cartilage and subchondral bone (two to eight millimeters thick) from the lateral femoral condyles was investigated. By means of morphological, histochemical, autoradiographic, and biochemical studies, the grafts were compared with sham and normal controls. When adequately fixed, the grafts remained viable and functionally and structurally intact during the twelve months of the experiment. The subchondral bone underwent rapid replacement in less than six weeks without loss of its supportive function. Resurfacing of a joint using an osteochondral graft is feasible in rabbits.
D000818:Animals; D002358:Cartilage, Articular / Q000166:cytology / Q000637:transplantation*; D007596:Joints / Q000166:cytology / Q000601:surgery*; D011817:Rabbits; D013499:Surface Properties; D013997:Time Factors; D014182:Transplantation, Autologous