Radiopaque contrast media XXXI-Glucoside conjugation of iodophthalein in rabbit.
Report is given on the identification of the metabolites of the iodophthalein sodium (TIP) in rabbit. After i.v. administration two meabolites (S1 and S2) were excreted mostly in the bile, but both were also found in the urine. The TIP glucoronide (S1) is formed in much greater yield than the glucoside (S2). This latter is a further example of glucoside conjugation in mammals.
D000818:Animals; D002765:Cholecystography; D003287:Contrast Media / Q000008:administration & dosage / Q000378:metabolism*; D005960:Glucosides / Q000378:metabolism; D006868:Hydrolysis; D007275:Injections, Intravenous; D008297:Male; D010635:Phenolphthaleins / Q000008:administration & dosage / Q000378:metabolism*; D011817:Rabbits
D003287:Contrast Media; D005960:Glucosides; D010635:Phenolphthaleins