Colony formation in vitro by mouse blood monocytes.
Mouse blood monocytes were induced to proliferate and form discrete colonies of mononuclear phagocytes in liquid culutre. The proliferation of these cells in vitro required a factor or factors present in medium conditioned by L cells. For this class of colony-forming cells, the value of Do to gamma irradiation in vitro was 195 rads.
D000818:Animals; D001202:Ascitic Fluid; D001666:Binding Sites, Antibody; D002448:Cell Adhesion; D002455:Cell Division; D002478:Cells, Cultured; D004307:Dose-Response Relationship, Radiation; D004731:Endotoxins; D007074:Immunoglobulin G; D007739:L Cells; D051379:Mice; D008806:Mice, Inbred AKR; D008809:Mice, Inbred C3H; D009000:Monocytes / Q000276:immunology / Q000528:radiation effects
D004731:Endotoxins; D007074:Immunoglobulin G