Pure oestrogen-secreting feminizing adrenocortical adenoma.
A 6-year-old boy presented with gynaecomastia. There was no clinical or biochemical evidence of excessive androgenic or glucorticoid activity, but urinary oestrogen levels were raised. An adrenocortical adenoma, demonstrated by x-ray, was surgically removed. Oestrogen levels fell immediately. 3 years later the boy shows complete regression of the gynaecomastia and no signs of recurrence.
D000236:Adenoma / Q000150:complications* / Q000378:metabolism; D000306:Adrenal Cortex Neoplasms / Q000150:complications* / Q000378:metabolism; D000310:Adrenal Gland Neoplasms / Q000150:complications*; D002648:Child; D004967:Estrogens / Q000378:metabolism; D006177:Gynecomastia / Q000209:etiology*; D006801:Humans; D008297:Male
D004967:Estrogens