In vitro activity of cinoxacin, ampicillin, and chloramphenicol against Shigella and nontyphoid Salmonella.
The in vitro antibacterial activity of cinoxacin was compared with that of ampicillin and chloramphenicol against 26 strains of nontyphoid Salmonella and 44 strains of Shigella. Cinoxacin was found to have a lower minimal inhibitory concentration than ampicillin and chloramphenicol against all Salmonella and Shigella sonnei strains. Cinoxacin had minimal inhibitory concentrations similar to those of chloramphenicol but lower than those of ampicillin against Shigella flexneri and S. boydii strains.
D000667:Ampicillin / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D002701:Chloramphenicol / Q000494:pharmacology*; D004148:Dioxolanes / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D011724:Pyridazines / Q000494:pharmacology*; D012475:Salmonella / Q000187:drug effects*; D012760:Shigella / Q000187:drug effects*; D013045:Species Specificity
D000900:Anti-Bacterial Agents; D004148:Dioxolanes; D011724:Pyridazines; D002701:Chloramphenicol; D000667:Ampicillin