title: Plasmid-medicated aminoglycoside phosphotransferase of broad substrate range that phosphorylates amikacin.
abstract: A plasmid-mediated aminoglycoside phosphotransferase that phosphorylates amikacin has been detected in clinical isolates of Staphylococcus aureus. This enzyme does not confer detectable amikacin resistance to the strains.
mesh_terms: D000583:Amikacin / Q000378:metabolism*; D000617:Aminoglycosides / Q000378:metabolism*; D005111:Extrachromosomal Inheritance; D007612:Kanamycin / Q000031:analogs & derivatives*; D010770:Phosphotransferases / Q000378:metabolism*; D010957:Plasmids; D013210:Staphylococcus / Q000201:enzymology
chemical_list: D000617:Aminoglycosides; D007612:Kanamycin; D000583:Amikacin; D010770:Phosphotransferases