title: [Nevus spilus. A histopathological study (author's transl)].
abstract: In the past, the nevus spilus was differently interpreted. Ito and Hamada, however, limited this term to a pigmented macule that had darker speckles within it. This newer definition is a useful one in clinical diagnostics. But histopathologically this lesion seems not to be an entity. A review of the literature and the present study suggest that it is in all probability a café-au-lait-nevus of neurofibromatosis-type. The darker spots are different in their histopathologic structures. They are nevus-cell-nevi, nevoid lentigines, epidermal pigmented macules or localized pigment disturbances with melaninincontinence following inflammatory prozesses.
mesh_terms: D000368:Aged; D001706:Biopsy; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D009508:Nevus, Pigmented / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*
vernacular_title: Beitrag zur Histopathologie des Naevus spilus