[The activity of L-cysteine aminopeptidase (Oxytocinase) during premature labour and tocolytic treatment (author's transl)].
The normal levels of L-Cysteine aminopeptidase in the maternal serum from 20 to 41 weeks gestation were tested in 240 samples of serum. The normal levels rise from 0.82 mU/ml at 24 weeks to 4.63 mU/ml at term. In 14 patients with premature labour the enzyme levels were tested during the treatment to inhibit labour with fenotero-hydrobromide. There was no decrease of oxytocinase as a cause of the onset of premature labour. During treatment to inhibit labour the L-Cysteine aminopeptidase showed no deviatiameter of placental function even in patients undergoing treatment to inhibit premature labour.
D000626:Aminopeptidases / Q000097:blood*; D010122:Cystinyl Aminopeptidase / Q000097:blood*; D005260:Female; D006801:Humans; D007752:Obstetric Labor, Premature / Q000201:enzymology*; D010920:Placenta / Q000502:physiology; D011247:Pregnancy; D012016:Reference Values; D013997:Time Factors
D000626:Aminopeptidases; D010122:Cystinyl Aminopeptidase
Aktivität der L-Zystin-Aminopeptidase bei vorzeitigem Wehenbeginin und Tokolyse