title: [Adverse reactions to drugs in hospitalized medical patients (author's transl)].
abstract: Prospective research showed that unwanted side-effects resulting from medical therapy were found in 20,6% of all patients hospitalized in our medical clinic during a period of one year. Part of these side-effects was considered a possible reason for admission to the hospital and a cause of complications during the clinical treatment. The side-effects were classified according to their severity, duration, symptomatology and pathogenesis. Furthermore, the frequency of side-effects was studied with regard to age, sex and groups of drugs. It was possible to predict about 80% of the side-effects by considering pharmacological properties and individual risk-factors. The careful integration of these criteria into the treatment plan and the observation of the course of the disease is the basis for calculating the probability of occurrence of side-effects.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects; D000959:Antihypertensive Agents / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects; D004232:Diuretics / Q000009:adverse effects; D004342:Drug Hypersensitivity; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D010347:Patient Care Planning; D011446:Prospective Studies; D012306:Risk; D012737:Sex Factors; D013256:Steroids / Q000009:adverse effects
chemical_list: D000925:Anticoagulants; D000959:Antihypertensive Agents; D000970:Antineoplastic Agents; D004232:Diuretics; D013256:Steroids
vernacular_title: Arzneimittelnebenwirkungen bei Patienten einer Medizinischen Klinik