Activity of creatine kinase isoenzyme MB in serum and red cell acetylcholinesterase variants in patients with Duchenne muscular dystrophy.
Activity of creatine kinase isoenzyme MB in serum and variants of red cell acetylcholinesterase were determined in patients with Duchenne muscular dystrophy, in other forms of Dystrophy and in family members of Duchenne patients and healthy controls. Creatine kinase isoenzyme MB was observed only in all cases of DMD as well as variants of red cell acetylcholinesterase characterized by so-called inhibitor numbers. Carriers of Duchenne muscular dystrophy can be distinguished from Duchenne patients and healthy controls by estimation of Acetylcholinesterase variants.
D000110:Acetylcholinesterase / Q000097:blood*; D002800:Cholinesterase Inhibitors / Q000097:blood; D003402:Creatine Kinase / Q000097:blood*; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D014644:Genetic Variation; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D008297:Male; D009132:Muscles / Q000201:enzymology; D009136:Muscular Dystrophies / Q000201:enzymology* / Q000235:genetics; D009206:Myocardium / Q000201:enzymology
D002800:Cholinesterase Inhibitors; D007527:Isoenzymes; D003402:Creatine Kinase; D000110:Acetylcholinesterase