title: The effect of dopamine infusion on insulin and glucagon secretion in man.
abstract: The effect of dopamine on the release of insulin and glucagon was investigated in eight adult subjects. Dopamine infused iv at a rate of 4 mug/kg/min X 2 hr, unaccompanied by cardiovascular changes, induced a prompt and significant increase in plasma insulin and glucagon and in plasma glucose levels. These findings suggest that dopamine may stimulate both alpha and beta cells.
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D004298:Dopamine / Q000494:pharmacology*; D004435:Eating; D005260:Female; D005934:Glucagon / Q000097:blood*; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male
chemical_list: D001786:Blood Glucose; D007328:Insulin; D005934:Glucagon; D004298:Dopamine