title: Fatal ECHO 24 infection in a patient with hypogammaglobulinemia: relationship to dermatomyositis-like syndrome.
abstract: Patients with deficient antibody-mediated immunity may develop a rare "dermatomyositis-like" syndrome, which is usually progressive and fatal. We have observed a child with hypogammaglobulinemia in whom a dermatomyositis-like syndrome was associated with a fatal, disseminated ECHO 24 infection. This association suggests that in some immunodeficient patients the fatal dermatomyositis-like syndrome is a manifestation of a viral infection in a compromised host. The use of maternal plasma, with a high titer of ECHO 24 neutralizing activity, was unsuccessful in arresting the progress of the infection.
mesh_terms: D000361:Agammaglobulinemia / Q000150:complications*; D002675:Child, Preschool; D003882:Dermatomyositis / Q000150:complications*; D004457:Echovirus Infections / Q000150:complications* / Q000276:immunology / Q000401:mortality / Q000628:therapy; D006801:Humans; D007106:Immune Sera / Q000008:administration & dosage; D007116:Immunization, Passive; D008297:Male; D013577:Syndrome
chemical_list: D007106:Immune Sera