Neonatal androgen injection changes open-field behavior of mice.
Newborn female mice of the C57BL/6J and BALB/cJ inbred strains and their reciprocal F1 hybrids were injected either with testosterone or with oil vehicle alone. Both the repeatablity and mean level of open-field activity scores over a 10-day test period increased in hormone-injected animals compared with controls. Increased activity due to hormonal treatment was greater in hybrid females than in inbred females. There was no consistent effect of hormonal treatment on open-field defecation.
D000818:Animals; D000831:Animals, Newborn; D001522:Behavior, Animal / Q000187:drug effects*; D004609:Eliminative Behavior, Animal / Q000187:drug effects; D005260:Female; D005838:Genotype; D006824:Hybridization, Genetic; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D012726:Sexual Behavior, Animal / Q000187:drug effects; D013739:Testosterone / Q000494:pharmacology*
D013739:Testosterone