Mycoplasma pneumoniae infection complicated by paroxysmal cold hemoglobinuria with anti-P specificity of biphasic hemolysin.
A 7-year-old boy with Mycoplasma Pneumoniae infection complicated by transitory paroxysmal cold haemoglobinuria (PCH) is described. The Donath-Landsteiner-antibody exhibited anti-P specificity; hemolytic activity was partially inhibited against papainized erythrocytes at 0 degrees C incubation temperature and increased from 8 degrees C upwards. The association of Mycoplasma pneumoniae infection with PCH has been described 4 times only and in one instance where specificity was stated it was anti-I.
D002648:Child; D003080:Cold Temperature; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications*; D006460:Hemolysin Proteins; D006801:Humans; D008297:Male; D009175:Mycoplasma Infections / Q000150:complications*; D010127:P Blood-Group System; D011014:Pneumonia / Q000150:complications*
D006460:Hemolysin Proteins; D010127:P Blood-Group System