Effect of imidocarb dipropionate and hemicastration on spermatogenesis in pony stallions.
The effect of imidocarb dipropionate [3, 3' bis-(2-imidazolin-2-yl) carbanilide dipropionate] on spermatogenesis in 3 pony stallions was studied. The drug alone had no deleterious effect on spermatogenesis when given intramuscularly 4 times at a dosage level of 4 mg/kg at 72-hour intervals. Hemicastration, with or without subsequent drug treatment, caused almost complete cessation of spermatogenesis 30 days after the operation.
D000818:Animals; D002224:Carbanilides / Q000494:pharmacology*; D002369:Castration / Q000662:veterinary*; D006736:Horses / Q000502:physiology*; D007095:Imidocarb / Q000494:pharmacology*; D008297:Male; D013091:Spermatogenesis / Q000187:drug effects*
D002224:Carbanilides; D007095:Imidocarb