title: Activity of 3beta-hydroxyteroid dehydrogenase in the postovulatory follicle of the domestic fowl (Gallus domesticus).
abstract: The activity of delta5-3beta-hydroxysteroid dehydrogenase (3beta-HSD) in the postovulatory follicle (POF) of the domestic hen was studied; it declined rapidly during the first 15 h after ovulation and then fell gradually until 52 h when there was no detectable activity. Comparison of 3beta-HSD and glucose 6-phosphate dehydrogenase activities in the theca and granulosa cells indicated that the changes in enzymatic activity can be attributed to the thecal component; the enzyme activity in granulosa cells was stable up to 35 h after ovulation. The results appear consistent with the hypothesis that the POF is a source of steroid hormones.
mesh_terms: D000818:Animals; D002645:Chickens / Q000502:physiology*; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006107:Granulosa Cells / Q000201:enzymology; D006913:Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D009929:Organ Size; D006080:Ovarian Follicle / Q000201:enzymology* / Q000502:physiology; D010060:Ovulation; D013799:Theca Cells / Q000201:enzymology; D013997:Time Factors
chemical_list: D006913:Hydroxysteroid Dehydrogenases; D005954:Glucosephosphate Dehydrogenase