title: Severe persistent inclusion conjunctivitis in a young child.
abstract: A 14-month-old girl had inclusion conjunctivitis although there had been no signs or symptoms that required medical attention in her first year. By 2 1/2 years of age, the child had extensive pannus and corneal scarring that severely reduced vision. The infection was caused by a genital strain of Chlamydia trachomatis, TRIC type E, that was probably acquired at birth. Although genitally transmitted chlamydial strains normally cause a self-limiting inclusion conjunctivitis in areas where trachoma is not endemic, this case illustrates that they may occasionally cause severe trachoma. Possibly local idoxuridine (IDU) treatment (administered to this patient before the correct diagnosis was made) contributed to the severity of this infection.
mesh_terms: D002675:Child, Preschool; D002692:Chlamydia trachomatis / Q000276:immunology / Q000302:isolation & purification; D003235:Conjunctivitis, Inclusion / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007065:Idoxuridine / Q000009:adverse effects; D007223:Infant; D007635:Keratitis, Dendritic / Q000175:diagnosis; D014141:Trachoma / Q000175:diagnosis
chemical_list: D007065:Idoxuridine