title: Pharmacogenetics in keratoconus.
abstract: Genetic markers such as phenylthiourea (PTC) taste has been used as a simple test in genetically determined diseases. A solution of 8.1 mg PTC in 100 ml of water was used as the antimode. The incidence of nontasters in the 50 keratoconus patients tested was similar to that found in the normal population. Under the conditions of this study, a common genetic basis between PTC taste testing and keratoconus is definitely not present.
mesh_terms: D006801:Humans; D007640:Keratoconus / Q000235:genetics*; D010641:Phenotype; D010670:Phenylthiourea; D013649:Taste
chemical_list: D010670:Phenylthiourea