Recurrent hemorrhage from corpus luteum during anticoagulant therapy.
A 43-year old woman had recurrent massive intraperitoneal hemorrhage from rupture of a hemorrhagic corpus luteum in two successive menstrual cycles while receiving anticoagulant therapy. Left oophorectomy was performed on the first occasion and right salpingo-oophorectomy with left salpingectomy on the second. While the precise incidence cannot be determined, rupture from a hemorrhagic corpus luteum appears to be a rare but potentially catastrophic complication of anticoagulant therapy. Hence possible ovarian hemorrhage should be considered in women of reproductive age receiving heparin or sodium warfarin therapy.
D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects*; D003338:Corpus Luteum; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D010049:Ovarian Diseases / Q000139:chemically induced; D012422:Rupture, Spontaneous / Q000139:chemically induced; D014859:Warfarin / Q000009:adverse effects
D000925:Anticoagulants; D014859:Warfarin