title: Effect of ouabain on reinnervating mammalian skeletal muscle.
abstract: The resting membrane potential (RMP) of denervated mammalian muscle fibers increases when reinnervation occurs. This recovery of RMP is temporally associated with the return of a ouabain-sensitive fraction of the RMP. The data suggest that the activity of an electrogenic pump within the sarcolemma is, either directly or indirectly, under neurotrophic regulation.
mesh_terms: D000818:Animals; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects; D009121:Muscle Denervation; D009132:Muscles / Q000187:drug effects / Q000294:innervation*; D010042:Ouabain / Q000494:pharmacology*; D051381:Rats; D013997:Time Factors
chemical_list: D010042:Ouabain