title: [Clinical signs and therapy of familial polyposis of the colon and recutum (author's transl)].
abstract: Familial polyposis of the colon and rectum does always present an absolute indication for immediate total colectomy because of the predictable malignant degeneration. The patient concerned as well as his family have to be examined and treated if necessary. 12 such cases have been operated upon in the surgical Department of the University of Mainz Medical School. In 4 cases proctocolectomy with terminal ileostomy were performed, in 7 cases ileorectostomies. The procedure of mucosectomy with subsequent pulling of the terminal ileum through the colon (Hochen-egg and Reifferscheid) has been tried by us so far only in animals. Since a terminal, life-long ileostoma does present a considerable disadvantage for the mostly younger patients we did perform in most cases an ileo-rectal end-to-end anastomosis. This procedure can be looked upon as adequate cancer prophylaxis if control rectoscopies are performed regularly in cooperative patients.
mesh_terms: D000328:Adult; D003082:Colectomy; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000601:surgery; D005260:Female; D006801:Humans; D007081:Ileostomy; D007414:Intestinal Neoplasms / Q000601:surgery; D007417:Intestinal Polyps / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000601:surgery; D012007:Rectum / Q000601:surgery
vernacular_title: Klinik und Therapie der familiaären Polyposis coli et recti