Muscle nuclear changes in fetuses at risk for Duchenne muscular dystrophy.
Muscle nuclear size was found to be significantly greater in fetuses at risk for Duchenne muscular dystrophy than in normal male fetuses of comparable gestational age. This supports the contention that the disease is already manifest in utero by the second trimester of pregnancy.
D002467:Cell Nucleus / Q000473:pathology*; D005260:Female; D005333:Fetus / Q000473:pathology*; D006801:Humans; D008297:Male; D009132:Muscles / Q000196:embryology / Q000473:pathology*; D009136:Muscular Dystrophies / Q000196:embryology* / Q000235:genetics; D011247:Pregnancy; D012306:Risk