Short-term effects of norethisterone oenanthate and medroxyprogesterone acetate on glucose, insulin, growth hormone, and lipids.
The effects on carbohydrate and lipid metabolism in 24 healthy female subjects of the long-acting steroid contraceptives norethisterone oenanthate (200 mg) (11 subjects) and depo-medroxyprogesterone acetate (150 mg) (13 subjects) were studied. The subjects were between the ages of 18 and 25 years, with a history of normal menstrual periods. Pretreatment levels of plasma cholesterol, plasma triglycerides, phospholipids, blood glucose, insulin, and growth hormone were compared with those obtained 3 weeks and 12 weeks after the initial injections. There were no statistically significant differences from the pretreatment levels in any of the values obtained at 3 weeks and 12 weeks in either group.
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D005260:Female; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D007273:Injections, Intramuscular; D007328:Insulin / Q000097:blood*; D008055:Lipids / Q000097:blood*; D008525:Medroxyprogesterone / Q000008:administration & dosage / Q000494:pharmacology*; D009640:Norethindrone / Q000008:administration & dosage / Q000494:pharmacology*
D001786:Blood Glucose; D007328:Insulin; D008055:Lipids; D013006:Growth Hormone; D008525:Medroxyprogesterone; D009640:Norethindrone