title: The place of irradiation in the management of the primary lesion in head and neck cancers.
abstract: Lesions of the skin are best excised except for specific locations where surgical excision would not likely produce disease-free margins and/or would require extensive plastic repair. A control rate of 90% for T1 lesions and 80% for T2 lesions is obtained with irradiation in the squamous cell carcinomas of the upper respiratory and digestive tract. Heavy smokers and/or severe alcoholics may be preferably treated surgically. The control rates in the T3 and T4 lesions are unsatisfactory with either irradiation or surgery alone. Pre- or postoperative irradiation combined with the appropriate surgical procedure improves the local control rates and to some extent the survival rates. Postoperative irradiation for the highly malignant tumors of the salivary gland reduces the local failure rate from 36% to 11%. The facial nerve can be preserved unless it is grossly involved.
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D005770:Gastrointestinal Neoplasms / Q000532:radiotherapy; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy; D008048:Lip Neoplasms / Q000532:radiotherapy; D009062:Mouth Neoplasms / Q000532:radiotherapy; D010610:Pharyngeal Neoplasms / Q000532:radiotherapy; D011879:Radiotherapy Dosage; D012142:Respiratory Tract Neoplasms / Q000532:radiotherapy; D012468:Salivary Gland Neoplasms / Q000532:radiotherapy; D012878:Skin Neoplasms / Q000532:radiotherapy