title: The effect of wheat fibre on plasma lipids and faecal steroid excretion in man.
abstract: 1. The effect of isoenergetic substitution of bran and wholemeal bread for white flour and white bread was investigated in six healthy volunteers in a metabolic unit. 2. A 21 d high-fibre experimental period was preceded and followed by a 14 d control period, so that each experiment lasted 7 weeks. Blood samples were taken on each of the last 3 d and faeces collected (using carmine markers) for the last 6 d of each diet period. 3. Plasma cholesterol, triglycerides and serum calcium concentrations were not altered by the addition of wheat fibre. 4. Wheat fibre caused a significant increase in faecal bulk and frequency. Faecal steroid excretion was the same in the last week of the first control and the high-fibre periods but increased in the subsequent control period.
mesh_terms: D000328:Adult; D001647:Bile Acids and Salts / Q000378:metabolism; D002118:Calcium / Q000097:blood; D002482:Cellulose; D002784:Cholesterol / Q000097:blood; D004043:Dietary Fiber; D005243:Feces / Q000032:analysis; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D009747:Nutritional Physiological Phenomena; D014280:Triglycerides / Q000097:blood; D014908:Triticum
chemical_list: D001647:Bile Acids and Salts; D004043:Dietary Fiber; D008055:Lipids; D014280:Triglycerides; D002482:Cellulose; D002784:Cholesterol; D002118:Calcium