An assessment of the bacteriological activity of Locabiotal (Fusafungine) --a non-systemic antibiotic.
Various tests were performed to establish the bacteriological potency of Locabiotal, an aerosol for local application to the nose and throat containing fusafungine. Using impregnated filter paper on a plate of solid sensitivity media considerable inhibition of the growth of common pathogens was shown. Plates of nasal swabs from adults and buccal swabs from children showed similar inhibition. Further tests after the application of the spray to the nose and throat indicated that inhibition lasts for at least eight hours.
D000328:Adult; D000336:Aerosols; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000188:drug therapy; D002177:Candidiasis / Q000188:drug therapy; D002648:Child; D047630:Depsipeptides; D006801:Humans; D008826:Microbial Sensitivity Tests; D012137:Respiratory System / Q000382:microbiology; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000382:microbiology
D000336:Aerosols; D000900:Anti-Bacterial Agents; D047630:Depsipeptides; C014001:fusafungin