Stimulation of interferon production in mice and in mouse spleen leukocytes by analogues of BL-20803.
Various structural analogues of the interferon inducer BL-20803 exhibited close agreement between ability to stimulate interferon production in the intact mouse and in cultures of spleen adherent leukocytes.
D000634:Aminoquinolines / Q000494:pharmacology*; D000818:Animals; D007369:Interferon Inducers / Q000494:pharmacology*; D007372:Interferons / Q000096:biosynthesis*; D007962:Leukocytes / Q000187:drug effects / Q000378:metabolism*; D051379:Mice; D011720:Pyrazoles / Q000494:pharmacology; D013154:Spleen / Q000166:cytology* / Q000378:metabolism; D013268:Stimulation, Chemical
D000634:Aminoquinolines; D007369:Interferon Inducers; D011720:Pyrazoles; D007372:Interferons