Hypertrophy of pulmonary arteries and arterioles with cor pulmonale in rats induced by seneciphylline, a pyrrolizidine alkaloid.
D000818:Animals; D006321:Heart / Q000187:drug effects; D006984:Hypertrophy / Q000139:chemically induced; D008099:Liver / Q000187:drug effects / Q000473:pathology; D008168:Lung / Q000098:blood supply / Q000187:drug effects / Q000473:pathology; D008297:Male; D009206:Myocardium / Q000473:pathology; D011651:Pulmonary Artery / Q000473:pathology; D011660:Pulmonary Heart Disease / Q000473:pathology*; D011763:Pyrrolizidine Alkaloids / Q000494:pharmacology; D051381:Rats
D011763:Pyrrolizidine Alkaloids