Uptake of noradrenaline in high altitude native's heart.
Uptake of 3H-noradrenaline by the heart was studied with sections of isolated atria obtained from high or lowlanders. In native highlanders, affinity for 3H-noradrenaline by human atria is more significant than in lowlanders. Furthermore, the Michaelis Menten constant is lower in high altitude native's heart.
D000222:Adaptation, Physiological; D000328:Adult; D000531:Altitude; D001692:Biological Transport; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D008875:Middle Aged; D009206:Myocardium / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism*
D009638:Norepinephrine