[Alteration of the electrophysiologic characteristics of the neurons of the great pseudo-equine leech after increasing the intracellular concentration of sodium ions].
Changes of membrane potential (MP), amplitude of action potential (AAP) and continuence of AP (CAP) of identified neurons of leech Haemopis sanguisuga have been investigated at high intracellular Na+ concentration. It has been shown that a moderate increase of intracellular Na+ concentration leads to hyperpolarization of the membrane to 15 mV and a certain increase of AAP and CAP. A further increase of [Na+]in leads to a sharp decrease of AAP and small decrease of CAP. Possible mechanisms of the phenomena described are discussed.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D007865:Leeches / Q000166:cytology*; D008564:Membrane Potentials / Q000187:drug effects*; D009474:Neurons / Q000187:drug effects*; D012964:Sodium / Q000494:pharmacology*
D012964:Sodium
Izmeneniia élektrofiziologicheskikh kharakteristik neĭronov bol'shoĭ lozhnokonskoĭ piiavki pri povyshenii vnutrikletochnoĭ kontsentratsii ionov natriia.