title: Recurrent abortion associated with a balanced 22;22 translocation, or isochromosome 22q in a monozygous twin.
abstract: A 45,XX,t(22;22)(p11;q11) or 45,XX,i(22q) chromosomal rearrangement was found in a woman with a history of recurrent abortion. A twin sister did not have the translocation even though marker studies indicate that the twins are probably monozygotic.
mesh_terms: D000026:Abortion, Habitual / Q000235:genetics*; D000328:Adult; D002869:Chromosome Aberrations; D002904:Chromosomes, Human, 21-22 and Y; D005260:Female; D006801:Humans; D011247:Pregnancy; D014178:Translocation, Genetic; D014430:Twins, Monozygotic