title: Kinetic behaviour of microsomal styrene monooxygenase and styrene epoxide hydratase in different animal species.
abstract: The apparent Km and Vmax values of styrene epoxide forming monooxygenase and styrene epoxide hydratase have been evaluated in the liver microsomes of male rats, mice, guinea-pigs and rabbits. Epoxide hydratase gave much higher and more uniform Km values than the monooxygenase in the species considered.
mesh_terms: D000818:Animals; D002273:Carcinogens / Q000378:metabolism; D004851:Epoxide Hydrolases / Q000378:metabolism*; D006168:Guinea Pigs; D006836:Hydro-Lyases / Q000378:metabolism*; D007700:Kinetics; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D010088:Oxidoreductases / Q000378:metabolism*; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013343:Styrenes / Q000378:metabolism*
chemical_list: D002273:Carcinogens; D013343:Styrenes; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D004851:Epoxide Hydrolases; D006836:Hydro-Lyases