Role of Friend-associated lymphatic leukemia virus in immunization against Friend leukemia complex.
Mice inoculated with Friend leukemia complex (FLC) pretreated with concanavalin A are resistant to FLC challenge only when they have become infected with the FLC-associated lymphatic leukemia virus (LLV). In interpreting states of resistance to FLC induced by various immunizing procedures, the possibility that immunity is sustained by an unrecognized LLV infection should always be considered.
D000818:Animals; D003208:Concanavalin A; D005622:Friend murine leukemia virus / Q000276:immunology*; D007114:Immunization; D007942:Leukemia, Experimental / Q000276:immunology*; D007945:Leukemia, Lymphoid / Q000276:immunology*; D051379:Mice / Q000276:immunology; D009929:Organ Size; D013154:Spleen / Q000473:pathology
D003208:Concanavalin A