The effect of intrahippocampal injections of serotonin on bioelectrical activity of Gyrus cinguli and amygdaloid nucleus in the rabbit.
The effect of injection of serotonin (5-HT), dissolved in 2 mul of bidistilled water, into hippocampus was studied in rabbits with chronically implanted electrodes and cannulas. Bioelectric activity of gyrus cinguli, amygdaloid nucleus, and dorsal hippocampus was recorded. 5-HT (10--20 mug) inhibited the electrical activity of the structures investigated, and this inhibition was accompanied by a suppression of locomotor activity or sleep.
D000679:Amygdala / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D004347:Drug Interactions; D004569:Electroencephalography; D004594:Electrophysiology; D006179:Gyrus Cinguli / Q000187:drug effects / Q000502:physiology*; D006624:Hippocampus / Q000187:drug effects / Q000502:physiology; D007267:Injections; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D009526:Nialamide / Q000008:administration & dosage / Q000494:pharmacology; D011817:Rabbits; D011985:Receptors, Serotonin / Q000187:drug effects; D012701:Serotonin / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors
D011985:Receptors, Serotonin; D012701:Serotonin; D009526:Nialamide