The vectorcardiogram in subjects with sex chromosome aneuploidy.
Vectorcardiographic variables have been studied in patients with sex chromosome abnormalities and compared with normal controls. Several of these variables were found to be correlated with the number of sex chromosomes in the karyotype, some being related to the number of X chromosomes, some to the number of Y chromosomes, and others to both. The variables concerned included time intervals and vector magnitudes in both the QRS and ST-T wave complexes. The heart rate itself proved dependent on both the X and the Y chromosome complements. The correlations could not be explained by age, height, or weight differences between the seven different karyotype groups studied. The dependences of variables other than the heart rate remained after correction for between-group heart rate differences. The findings are discussed.
D000328:Adult; D000782:Aneuploidy; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D012729:Sex Chromosome Aberrations / Q000503:physiopathology*; D014672:Vectorcardiography