title: [Cytogenetic activity of the pesticides phthalophos, chlorophos and gardona in a culture of human lymphocytes].
abstract: The cytogenetic action of three phosphoorganic pesticides, imidan, dipterex and gardona, in cultured human lymphocytes is studied. It is found that all the sunstances induce the signficant increase in the frequency of metaphases with chromosomes aberrations as compared with the control level. Maximal effects in vitro qere 6,0; 4,8 and 4,0% of aberrant cells for imidan, dipterex and gardona respectively. All investigated substances had a weak mutagenic activity in human lymphocyte culture.
mesh_terms: D000328:Adult; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D006801:Humans; D007306:Insecticides / Q000633:toxicity*; D008297:Male; D010706:Phosmet / Q000633:toxicity*; D013751:Tetrachlorvinphos / Q000633:toxicity*; D014236:Trichlorfon / Q000633:toxicity*
chemical_list: D007306:Insecticides; D014236:Trichlorfon; D013751:Tetrachlorvinphos; D010706:Phosmet
vernacular_title: Tsitogeneticheskaia aktivnost' pestitsidov ftalofosa, khlorofosa i gardony v kul'ture limfotsitov cheloveka.