Phosphonolipids. XXVII. Synthesis of phosphonic acid analogs of saturated and unsaturated L-alpha-lecithins.
A procedure for the synthesis of saturated and unsaturated phosphonolecithin from the cadmium chloride complex of sn-glycerol-3-(2-trimethylammoniumethyl)-phosphonate is reported. The phosphonolecithins are obtained by acylating sn-glycerol-3(2-trimethylammoniumethyl)-phosphonate-cadmium chloride complex with fatty acid chloride and pyridine at low temperature. The preparation of the disteraroyl, dipalmitoyl, dimyristoly, and dioleoyl phosphonolecithins by this procedure is described.
D008722:Methods; D063065:Organophosphonates; D010169:Palmitic Acids; D010713:Phosphatidylcholines / Q000138:chemical synthesis*; D013229:Stearic Acids
D063065:Organophosphonates; D010169:Palmitic Acids; D010713:Phosphatidylcholines; D013229:Stearic Acids