title: [Hygieno-toxicologic study of polyamide film P-12 intended for use in the food industry].
abstract: A hygienic-toxicological study of the polyamide film II-12, developed at the Scientific-Research Institute of Plastics and intended for use in food industry as a packing material was carried out. Pertinent sanitary and chemical investigations have brought evidence that the II-12 film does not adversely affect the organoleptic characteristics of model solution, while erosion of organic substances therefrom is insignificant. A long-term toxicological experiment staged on 2 generations of rats in which biochemical and histological factors, as well as those characterizing the possibility of an embryotoxic action and finfluence on the reproductive function of the animals had been determined, did not reveal any untoward changes in the test animals as compared to the controls.
mesh_terms: D000014:Abnormalities, Drug-Induced; D000577:Amides / Q000633:toxicity*; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury; D005260:Female; D005506:Food Contamination / Q000517:prevention & control*; D006402:Hematologic Diseases / Q000139:chemically induced; D007674:Kidney Diseases / Q000139:chemically induced; D008297:Male; D011108:Polymers; D051381:Rats
chemical_list: D000577:Amides; D011108:Polymers
vernacular_title: Gigieno-toksikologicheskoe izuchenie poliamidnoĭ plenki P-12 prednaznachennoĭ dlia primeneniia v pishchevoĭ promyshlennosti.