Synthetic analogs of natural prenylated and chromene chalcones.
A number of synthetic analogs of the prenylated and chromene chalcones isolated from lonchocarpus neuroscapha (Leguminosae) were obtained by condensation of prenylated acetophenones with substituted benzaldehydes. The antibacterial activity of these products was studied and correlated with their structure.
D000098:Acetophenones / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001547:Benzaldehydes / Q000494:pharmacology; D002599:Chalcone / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D011427:Propiophenones / Q000031:analogs & derivatives*
D000098:Acetophenones; D001547:Benzaldehydes; D011427:Propiophenones; D002599:Chalcone