Geographic dark posterior fundus patches.
Nine cases of a newly recognized, probably not uncommon, anomaly of the retinal pigment epithelium have been observed over a four-year period. The lesions occur predominantly in black subjects. Some degree of hemoglobinopathy was present in all the black patients with geographic dark posterior fundus patches. Almost all of the patients were young (6 to 26 years old) but two were 50 years of age. In three patients the patches grew larger. They did not interfere with vision or visual fields and did not appear to be involved with vitreous abnormalities. Fluorescein angiography was normal. In three patients, an electroretinogram gave subnormal results to all stimulus intensities; it was normal in one patient.
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006453:Hemoglobinopathies / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye