title: The generation and identification of the hemolysin of Trypanosoma congolense.
abstract: The hemolytic activity of Trypanosoma congolense appears to be due to the presence of free fatty acids generated by the action of phospholipase A on endogenous phosphatidyl choline. Some lysolecithin also contributes to the lytic activity. Trypanosoma lewisi, being devoid of phospholipase A, does not generate free fatty acids and is therefore non-hemolytic.
mesh_terms: D000818:Animals; D004912:Erythrocytes; D005230:Fatty Acids, Nonesterified / Q000032:analysis; D006460:Hemolysin Proteins / Q000302:isolation & purification; D006461:Hemolysis; D008049:Lipase / Q000378:metabolism; D008244:Lysophosphatidylcholines; D010740:Phospholipases / Q000378:metabolism; D012756:Sheep; D014345:Trypanosoma
chemical_list: D005230:Fatty Acids, Nonesterified; D006460:Hemolysin Proteins; D008244:Lysophosphatidylcholines; D010740:Phospholipases; D008049:Lipase