Effect of cadmium on polyribosome structure and function in mouse liver.
Cadmium chloride injected to mice (20 micronmoles/kg) provokes in the livers a degradation of polyribosomes and diminishes their protein synthetic ability measured in vitro. CdCl2 added in a final concentrations between 30 and 100 micron to the protein synthetic cell-free system derived from livers of control mice inhibits its activity.
D000818:Animals; D002104:Cadmium / Q000494:pharmacology*; D002474:Cell-Free System; D003600:Cytosol / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000648:ultrastructure; D008297:Male; D051379:Mice; D011132:Polyribosomes / Q000187:drug effects* / Q000378:metabolism; D014176:Protein Biosynthesis
D002104:Cadmium