Characterization of prostatic carcinoma among blacks: a continuation report.
A clinical and pathologic comparison of carcinoma of the prostate in a high-risk US (Washington, DC) black population and in a low-risk Nigerian (Ibadan) black population is presented. Fifty-two percent of American patients were in clinical stages I and II, whereas only 10% of Nigerian patients were in the same stages. Testosterone and estradiol blood levels were significantly lower (P less than 0.05) in patients with carcinoma of the prostate from Ibadan compared with American black prostate cancer patients from Washington, DC. Age-standardized incidence rates (world standard) for 1000 autopsies for micro (incidental)-carcinoma were approximately equal in American and African black men. The incidence rate of invasive carcinoma was, however, even after adjustment for age, higher in American black men than in African men.
D001741:Black or African American; D000367:Age Factors; D000368:Aged; D044383:Black People; D002277:Carcinoma / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D004219:District of Columbia; D004958:Estradiol / Q000378:metabolism; D004970:Estrone / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D013739:Testosterone / Q000378:metabolism
D004970:Estrone; D013739:Testosterone; D004958:Estradiol