[Sleep pattern in parkinsonism. Preliminary communication].
The sleep pattern was studied in 10 patients with Parkinson's disease with polygraphic recording of EEG tracings, eyeball movements, EMG from the chin area and EEG during two overnight investigations. The results were compared with the sleep pattern obtained in a similar way in 5 healthy subjects in the same age group. Prolongation of the time of falling asleep and reduction of the percent proportion of the deepest sleep phases (III and IV slow-wave phases and paradoxical phase) were observed. The possible biochemical substrate of these changes (low levels of dopamine and serotonin) is suggested. The author compared also the sleep pattern obtained in two consecutive sleep records in the same subjects discussing the so-called first-night effect.
D000328:Adult; D000368:Aged; D004298:Dopamine / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism; D012890:Sleep; D012894:Sleep Stages; D012893:Sleep Wake Disorders / Q000209:etiology*
D012701:Serotonin; D004298:Dopamine
Obraz snu w chorobie Parkinsona. Obserwacje wstepne.