title: The occurrence of 2-hydroxyisovaleric acid in patients with lactic acidosis and ketoacidosis.
abstract: Examination of urine samples by capillary column gas chromatography and mass spectrometry showed the presence of 2-hydroxyisovaleric acid together with trace amounts of the three branched-chain 2-keto acids in five patients with lactic and ketoacidosis. None of these compounds was detected in urine from healthy controls.
mesh_terms: D000138:Acidosis / Q000652:urine*; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002849:Chromatography, Gas; D005260:Female; D006801:Humans; D006880:Hydroxy Acids / Q000652:urine*; D006885:Hydroxybutyrates / Q000652:urine; D007223:Infant; D007651:Keto Acids / Q000652:urine; D007773:Lactates / Q000652:urine; D008297:Male; D013058:Mass Spectrometry; D014631:Valerates / Q000652:urine*
chemical_list: D006880:Hydroxy Acids; D006885:Hydroxybutyrates; D007651:Keto Acids; D007773:Lactates; D014631:Valerates