Determination of MAC for halothane, cyclopropane and ether in the rabbit.
Rabbits have a high rate of ventilation which makes it difficult to obtain a sample of end-tidal gas by the usual procedures. An occlusion technique was developed which provided a gas sample equivalent to an end-tidal gas sample. MAC values were determined using this sampling method. The values obtained +/- SEM were: cyclopropane 15.6 +/- 1.7%, halothane 0.63 +/- 0.06% and ether 2.7 +/- 0.2%.
D000818:Animals; D003521:Cyclopropanes / Q000032:analysis*; D004986:Ether / Q000032:analysis*; D005019:Ethyl Ethers / Q000032:analysis*; D006221:Halothane / Q000032:analysis*; D008297:Male; D008722:Methods; D011650:Pulmonary Alveoli / Q000032:analysis*; D011817:Rabbits; D012129:Respiratory Function Tests / Q000379:methods
D003521:Cyclopropanes; D005019:Ethyl Ethers; D004986:Ether; D006221:Halothane