title: [Kidney changes in experimental obesity].
abstract: In a survey renal changes in human obesity as well as in experimental obesity of laboratory animals are discussed. Own results are described about a comparison of biochemical and morphological studies on an experimental model of dietary-induced obesity after long-time feeding of a high-fat diet. Obese rats show normal concentrations of plasma proteins after feeding of a high-fat diet of some weeks. Urea-nitrogen levels are not modified as compared to control animals. Despite the mean levels of creatinine concentration in the dynamic and static phase of obesity are not different, some obese rats show increased creatinine values in the dynamic phase. Our histological studies reveal no pathological abnormalities of renal structures and blood vessels.
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000032:analysis; D004041:Dietary Fats; D006949:Hyperlipidemias / Q000209:etiology; D007668:Kidney / Q000473:pathology*; D008297:Male; D009401:Nephrosis / Q000209:etiology; D009765:Obesity / Q000209:etiology / Q000473:pathology*; D009929:Organ Size; D051381:Rats
chemical_list: D001798:Blood Proteins; D004041:Dietary Fats
vernacular_title: Nierenveränderungen bei tierexperimenteller Fettsucht.