Inhibitory effects of xenogeneic antiserum on the growth of Moloney virus-induced sarcomas.
An antiserum was developed in rabbits by injections of a virus concentrate from Moloney murine sarcomas. Passive transfer of this antiserum attenuated the growth of both primary and transplanted Moloney murine sarcomas. It also facilitated tumor regression and increased survival times of young mice with primary Moloney sarcomas.
D000818:Animals; D000912:Antibodies, Neoplasm; D000914:Antibodies, Viral; D005260:Female; D007116:Immunization, Passive; D007167:Immunotherapy; D051379:Mice; D008807:Mice, Inbred BALB C; D008979:Moloney murine leukemia virus / Q000276:immunology*; D009368:Neoplasm Transplantation; D011817:Rabbits; D012513:Sarcoma, Experimental / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D014185:Transplantation, Isogeneic; D014412:Tumor Virus Infections / Q000628:therapy*
D000912:Antibodies, Neoplasm; D000914:Antibodies, Viral