title: A very significant correlation between carcinogenic activity of polycyclic hydrocarbons and certain properties of their transition states in the range of the lowest triplet states of the DNA.
abstract: A very significant correlation between carcinogenic power of polycyclic aromatic hydrocarbons and their probability of photoinduced double resonance transitions in the UV-range of about 3 to 3.5 eV is shown. The resonance can be interpreted in terms of the lowest triplet state energy of thymine at 3.25 eV and the energy difference between the triplet states of A--T and G--C base pairs. The correlation has been predicted from a hypothesis which describes cell communication by photon interaction within a cell population.
mesh_terms: D002273:Carcinogens; D055598:Chemical Phenomena; D002621:Chemistry; D004247:DNA; D004735:Energy Transfer; D007259:Infrared Rays; D010777:Photochemistry; D011083:Polycyclic Compounds; D013329:Structure-Activity Relationship; D014466:Ultraviolet Rays
chemical_list: D002273:Carcinogens; D011083:Polycyclic Compounds; D004247:DNA