Use of normal daughters' and sisters' creatine kinase levels in estimating heterozygosity in Duchenne muscular dystrophy.
A modification is given of the original density function formula of EMERY and MORTON for estimating heterozygosity in X-linked Duchenne muscular dystrophy. This modification takes into account SCK levels in both normal sisters and normal daughters of a suspected carrier in families where there is only one affected male.
D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D005808:Genes, Recessive; D008040:Genetic Linkage; D006579:Heterozygote; D006801:Humans; D008297:Male; D009136:Muscular Dystrophies / Q000235:genetics*; D010375:Pedigree; D012744:Sex Ratio; D013223:Statistics as Topic
D003402:Creatine Kinase