An alternative method for the evaluation of organ weight experiments.
Previous work has suggested that the use of relative organ weights can lead to erroneous conclusions in toxicological experiments. A method of analysis involving very little extra experimentation is suggested and evaluated. Simulated results from rat organ weights indicate that the method is superior to the use of relative organ weights and leads to reliable conclusions being drawn about the treatment effects.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D005260:Female; D008297:Male; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D012107:Research Design; D013223:Statistics as Topic; D014116:Toxicology / Q000379:methods*