Isotope effect studies on the dehydrogenation of delta 1-tetrahydrocannabinol in the rat.
Isotope effect studies on the metabolic dehydrogenation of delta 1-tetrahydrocannabinol in rats are described and it is shown that this process is confined to a very short period following i.v. administration. The implications of this finding are discussed.
D000818:Animals; D002186:Cannabinoids / Q000097:blood*; D002187:Cannabinol / Q000097:blood*; D002250:Carbon Radioisotopes; D013759:Dronabinol / Q000097:blood*; D051381:Rats; D014316:Tritium
D002186:Cannabinoids; D002250:Carbon Radioisotopes; D014316:Tritium; D013759:Dronabinol; D002187:Cannabinol