title: Intermediates in the barnol biosynthesis in Penicillium baarnense.
abstract: By using appropriate 14C-labelled phenolic substances as precursors in feeding experiments the following steps in barnol biosynthesis have been established: acetate + malonate leads to 2,4-dihydroxy-6-ethyl-5-methylbenzaldehyde leads to 1,3-dihydroxy-4,6-dimethyl-2-ethylbenzene leads to barnol. P. baarnense can also reduce orcylaldehyde and 2,4-dihydroxy-5,6-dimethylbenzaldehyde to dimethylresorcinol and trimethylresorcinol, respecitively.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D003470:Culture Media; D010407:Penicillium / Q000254:growth & development / Q000378:metabolism*; D014992:Xylenes / Q000096:biosynthesis*
chemical_list: D003470:Culture Media; D014992:Xylenes