Oligosaccharides of the glycoprotein of rabies virus.
The number of oligosaccharide side chains on rabies virus glycoprotein (G-protein) was investigated. Analysis of glycopeptides obtained by protease digestion of desialated G-protein revealed three discrete glycopeptides. Comparison of the protease digestion products from desialated and from untreated G-protein indicated a heterogeneity among the glycopeptides in the sialic acid content. Two major tryptic glycopeptides were isolated from desialated rabies virus G-protein and analyzed after protease digestion; one contained two oligosaccharide side chains and the other contained a single oligosaccharide side chain.
D006020:Glycopeptides / Q000032:analysis; D006023:Glycoproteins / Q000032:analysis*; D009844:Oligosaccharides / Q000032:analysis*; D010447:Peptide Hydrolases / Q000378:metabolism; D011820:Rabies virus / Q000032:analysis*; D012794:Sialic Acids / Q000032:analysis; D014357:Trypsin / Q000378:metabolism; D014764:Viral Proteins / Q000032:analysis*
D006020:Glycopeptides; D006023:Glycoproteins; D009844:Oligosaccharides; D012794:Sialic Acids; D014764:Viral Proteins; D010447:Peptide Hydrolases; D014357:Trypsin