title: Valve replacement in children.
abstract: Since 1964, 27 valve replacements have been performed in patients who ranged from 5 months to 20 years of age. Fourteen underwent aortic valve replacement, 10 underwent mitral valve replacement, two had systemic atrio-ventricular valve replacement, and one had tricuspid valve replacement. Nineteen patients had congenital heart disease, five had rheumatic disease, and three had Marfan's syndrome. Starr-Edwards prostheses were used in 17 patients, Björk-Shiley prostheses in six, and procine xenografts in for. There were five early deaths and five late deaths. Patients were followed for 2 months to 6 years postoperatively (mean 2.1 years). All survivors showed clinical improvement. There were no episodes of thromboembolism. Minor bleeding, arrhythmias, and bacterial endocarditis occurred infrequently.
mesh_terms: D000293:Adolescent; D000818:Animals; D001021:Aortic Valve / Q000637:transplantation; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000401:mortality / Q000601:surgery*; D006350:Heart Valve Prosthesis / Q000401:mortality; D006801:Humans; D007223:Infant; D008297:Male; D008943:Mitral Valve / Q000637:transplantation; D011183:Postoperative Complications; D012214:Rheumatic Heart Disease / Q000401:mortality / Q000601:surgery*; D013552:Swine; D014183:Transplantation, Heterologous; D014261:Tricuspid Valve