Free fatty acids and arrhythmias following acute coronary artery occlusion in pigs.
The arrhythmogenic potential of elevated serum free fatty acids (FFA) was investigated in closed-chest pigs following acute coronary artery occlusion. Animals both with and without ventricular irritability before the FFA rise were studied. No significant increase in PVC frequency occurred and only 1 out of 17 animals developed ventricular fibrillation in the 60 min following acute FFA elevation. In this situation, FFA did not significantly influence the appearance of arrhythmias.
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000209:etiology*; D003327:Coronary Disease / Q000097:blood* / Q000150:complications; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D013552:Swine; D013997:Time Factors
D005230:Fatty Acids, Nonesterified