[Effect of estrogens on the concentration of carcinoembryonal antigen in the serum of rats with intestinal neoplasms and in the presence of non-specific injuries to its mucous membrane].
Carcinoembryonal antigen (CEA) was shown to be present in 70% of rats with tumours of the large intestine induced with 1,2-dimethyl-hydrazine and in rats with posttraumatic mucosa regeneration of the same organ. After treatment with estrogen--diethyl stilbestrol propionate (0.57 microgram/day for 6 days) the incidence of CEA finding in the serum of these rats was increased. In rats with an injured mucosa of the large intestine estrogen treatment prevented the natural decrease of CEA during the decline of regeneration.
D000818:Animals; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D004054:Diethylstilbestrol; D005260:Female; D007413:Intestinal Mucosa / Q000293:injuries*; D007414:Intestinal Neoplasms / Q000503:physiopathology*; D051381:Rats
D002272:Carcinoembryonic Antigen; D004054:Diethylstilbestrol
Vliianie éstrogenov na soderzhanie rakoémbrional'nogo antigena v syvorotke krovi krys s novoobrazovaniiami kishechnika i pri nespetsificheskikh povrezhdeniiakh ego slizistoĭ obolochki.