Hormonal manipulation of carrageenin-induced pyresis in rats,.
The intensity of the hyperthermic response in rats promoted by subplantar injections of 1 mg of carrageenin is directly related to the irritant properties of the type of carrageenin. The overall pyretic response is more dramatic in female rats than in male rats. Subtle changes in the time-course hyperthermic profiles are seen after hormonal modifications.
D000818:Animals; D002351:Carrageenan; D002369:Castration; D004958:Estradiol / Q000031:analogs & derivatives* / Q000494:pharmacology; D005260:Female; D005334:Fever / Q000139:chemically induced / Q000503:physiopathology*; D008297:Male; D051381:Rats; D012737:Sex Factors; D013329:Structure-Activity Relationship; D013739:Testosterone / Q000031:analogs & derivatives* / Q000494:pharmacology
D013739:Testosterone; D004958:Estradiol; D002351:Carrageenan