title: [Use of a computer for the optimal results of treatment of diabetes mellitus with insulin].
abstract: The authors present material on the optimization of diabetes mellitus treatment, with the aid of a computer. There were 320 patients under observation. Mathematical models describing the process of the patients treatment and permitting to pronosticate the blood and urine sugar level during the treatment were developed. The use of the imitation experiment on a computer permitted to test several therapeutic variants for the given patient and to choose the optimum one, leading to the most rapid compensation. The second task consisted in the maintenance in the patients of blood glucose variations within definite limits, in the course of 24 hours. An individual model of blood glucose dynamics in the course of 24 hours is set on the computer, and then the optimal scheme of insulin treatment is chosen. Practical testing of such scheme showed its efficacy.
mesh_terms: D003201:Computers; D003920:Diabetes Mellitus / Q000188:drug therapy*; D004341:Drug Evaluation; D006801:Humans; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use*; D008962:Models, Theoretical
chemical_list: D007328:Insulin
vernacular_title: Ispol'zovanie EVM dlia optimizatsii lecheniia sakharnogo diabeta insulinom.