Antioxidant-mediated reversal of ultraviolet light cytotoxicity.
Several antioxidants were tested for their protective effect in Chinese hamster embryo cell against ultraviolet light (UVL)-irradiation. Ascorbic acid, DL-alpha-tocopherol, butylated hydroxytoluene, and reduced glutathione were all shown to reverse UVL-induced cytotoxicity. At concentrations tested, no protective effect was detected when any of these antioxidants were added prior to UVL irradiation.
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured / Q000528:radiation effects*; D006224:Cricetinae; D003470:Culture Media; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D014466:Ultraviolet Rays / Q000009:adverse effects*
D000975:Antioxidants; D003470:Culture Media; D011837:Radiation-Protective Agents