Somatic segregation and Fanconi anemia.
A case of Fanconi anemia with terminal acute leukemia is reported. Clones with chromosome abnormalities were observed in bone marrow cells. The patterns of marker chromosome distribution in these clones suggests the occurrence of a somatic segregation mechanism.
D000208:Acute Disease; D000328:Adult; D000741:Anemia, Aplastic / Q000235:genetics*; D002869:Chromosome Aberrations; D005199:Fanconi Anemia / Q000235:genetics*; D005260:Female; D006801:Humans; D007938:Leukemia / Q000235:genetics