[Reserve production of renin by glomerular mesangial cells following experimental decrease in renal circulation].
The aorta was partially constricted between the origins of the two renal arteries in rats. The renin activity was studied separately in the capillary parts of the isolated glomeruli and in their arterioles. The renin activity was found in the capillary parts of the glomeruli 3 to 4 weeks after the constriction. The rough and smooth endoplasmic reticulum and the Golgi complex of the mesangial cells were activated at this period. The authors consider these results as a confirmation of the hypothesis on the reserve renin production by mesangial cells under prolonged decrease of renal circulation.
D000818:Animals; D001794:Blood Pressure; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D007678:Kidney Glomerulus / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats; D012078:Renal Artery Obstruction / Q000378:metabolism* / Q000473:pathology; D012083:Renin / Q000096:biosynthesis*
D012083:Renin
Rezervnaia produktsiia renina mezangial'nymi kletkami klubochka pri éksperimental'nom umen'shenii pochechnogo krovoobrashcheniia.