title: [Experimental study of chloroprene for carcinogenicity].
abstract: Chloroprene (2-chlorobutidiene 1,3) is an intermediate chemical product derived in the process of obtaining synthetic rubber. Chloroprene was shown by the experiments on mice and rats to be not carcinogenic. The application of chloroprene in animals by skin smears, subcutaneous injections, per os and intratracheal administration failed to induce any tumors in the experimental animals. No tumors were observed also in animals after using its combination with very small doses of dimethylbenz (a) anthracene.
mesh_terms: D000284:Administration, Oral; D000336:Aerosols; D000818:Animals; D002070:Butadienes / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000633:toxicity; D002273:Carcinogens; D004341:Drug Evaluation; D005260:Female; D007279:Injections, Subcutaneous; D008297:Male; D051379:Mice; D051381:Rats; D014132:Trachea
chemical_list: D000336:Aerosols; D002070:Butadienes; D002273:Carcinogens
vernacular_title: Eksperimental'noe izuchenie khloroprena na kantserogennost'.