[Effect of the quality characteristics of the fatty component of the diet on the fatty acid makeup of the erythrocytic and thrombocytic membranes in healthy persons].
Practically healthy males received rations in which principal sources of fat in the descending order were butter, sunflower and mustard oil. The influence of qualitative properties of the ration's fat on the lipids metabolism in the plasma and the coefficient of the metabolization effectiveness of essential fatty acids (CEM) of the food into the membranes lipids was studied. The CEM was calculated by studying the fatty acids composition of the erythrocytes and thrombocytes stroma. Inclusion in the ration of butter alone, raised the cholesterol level, a fall of the plasma phospholipids level and a significant drop of the CEM. Substitution of sunflower oil for butter led to normalization of these figures. Mustard oil had no effect. Changes in the CEM of the erythrocytes stroma proceeded slowly, significant differences having been discovered only after 6 weeks of the butter consumption. The thrombocytes CEM changed quickly, a stable fatty acids composition of thrombocytes with this ration being established by the end of the 2nd week. The qualitative properties of the ration's fat exercise a sufficiently strong influence on the effective metabolization of fatty acids in the food into the lipid structures of the erythrocytes and thrombocytes membranes in a healthy subject, it being characterized by the CEM changes.
D000328:Adult; D001792:Blood Platelets / Q000032:analysis*; D002462:Cell Membrane / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D004032:Diet; D004041:Dietary Fats / Q000008:administration & dosage / Q000378:metabolism*; D004910:Erythrocyte Membrane / Q000032:analysis*; D004912:Erythrocytes / Q000032:analysis*; D005227:Fatty Acids / Q000032:analysis*; D006801:Humans; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000097:blood; D013997:Time Factors
D004041:Dietary Fats; D005227:Fatty Acids; D008055:Lipids; D008074:Lipoproteins; D010743:Phospholipids; D002784:Cholesterol
Vliianie kachestvennykh osobennosteĭ zhirovogo komponenta ratsiona na zhirnokislotnyĭ sostav membran éritrotsitov i trombotsitov u zdorovykh liudeĭ.