[The necropsy, contribution to the knowledge of the undesirable effects of medications and toxic agents].
All the examples quoted demonstrate that in the field of toxicology, pathologic anatomy still offers the means of establishing the first links between macroscopic and microscopic lestions and physiology. The current trend in this disciplin is to look beyond the clinical symptom or morphologic disturbance and seek the causal biochemical interactions. Through the methods of systematic autopsy and electron microscopy of biopsy specimens, pathologic anatomy continues to provide the alarm signal for the pharmacologic warning system our modern environment demands.
D001344:Autopsy; D003078:Colchicine / Q000633:toxicity; D004071:Digitalis Glycosides / Q000633:toxicity; D064420:Drug-Related Side Effects and Adverse Reactions; D005026:Ethylene Glycols / Q000633:toxicity; D006801:Humans; D007668:Kidney / Q000473:pathology; D011042:Poisons; D011654:Pulmonary Edema / Q000150:complications; D011658:Pulmonary Fibrosis / Q000209:etiology / Q000473:pathology; D014116:Toxicology / Q000379:methods*
D004071:Digitalis Glycosides; D005026:Ethylene Glycols; D011042:Poisons; D003078:Colchicine
La necropsie, contribution à la connaissance des effets indésirables des médicaments et des toxiques.