Anophthalmos. Report of two cases.
Two infants were found to have bilateral anophthalmos and other congenital anomalies. Secondary anophthalmia was diagnosed in one patient who showed malformations of the brain and an absence of ocular tissues including the optic nerves. The other patient had degenerative (consecutive) anophthalmos; fragments of ocular tissues including the optic nerves were found in the orbits.
D000015:Abnormalities, Multiple; D000853:Anophthalmos / Q000196:embryology / Q000473:pathology; D001921:Brain / Q000002:abnormalities; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009410:Nerve Degeneration; D009900:Optic Nerve / Q000473:pathology; D009915:Orbit / Q000473:pathology; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011263:Pregnancy Trimester, Third; D014125:Toxoplasmosis, Congenital