Symptomatic hyponatraemia associated with tolbutamide therapy.
A case of hyponatraemic coma occurring in a patient with diabetes mellitus treated with tolbutamide is described. Although chlorpropamide is known to cause water retention in some circumstances, this is a less well recognized complication of tolbutamide therapy.
D003920:Diabetes Mellitus / Q000188:drug therapy; D006801:Humans; D007010:Hyponatremia / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D014044:Tolbutamide / Q000009:adverse effects* / Q000627:therapeutic use
D014044:Tolbutamide