Epileptic seizures induced by psychotropic drugs.
On the basis of information abstracted from case histories, 41 patients who had experienced epileptic seizures thought to be due either to treatment with psychiatric drugs or to withdrawal from sedative drugs were compared with a control group of patients. Those who had experienced seizures were more commonly first born and had a history of post-natal brain damage. During the week preceding the seizure there had been a marked increase in drug prescribing. The implications for drug management are discussed.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001722:Birth Order; D001925:Brain Damage, Chronic / Q000175:diagnosis; D002746:Chlorpromazine / Q000008:administration & dosage; D003975:Diazepam / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004569:Electroencephalography; D004827:Epilepsy / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000009:adverse effects*; D012651:Self Medication / Q000009:adverse effects; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis
D011619:Psychotropic Drugs; D003975:Diazepam; D002746:Chlorpromazine