Addison's disease with renal microangiopathy and renal failure (a new syndrome).
A syndrome comprising Addison's disease, renal microangiopathy and renal failure is described in two patients. The renal lesions manifested despite corticosteroid replacement therapy and were characterized by glomerular damage and thrombo-microangiopathic changes in afferent arterioles and intralobular arteries. Both patients died as a result of their renal disease.
D000224:Addison Disease / Q000150:complications*; D000328:Adult; D005260:Female; D006801:Humans; D007668:Kidney / Q000098:blood supply*; D007674:Kidney Diseases / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000150:complications*; D008875:Middle Aged; D013577:Syndrome; D014652:Vascular Diseases / Q000150:complications / Q000473:pathology