title: [Centro-pontine myelinolysis associated with diffuse lesions of the white matter. Water-electrolyte disturbances associated with diuretic therapy].
abstract: The authors report a case of centropontine myelinosis associated with demyelinising lesions of the tectum mesencephali, the cerebellum, the central grey nuclei and the white matter of the hemispheres. This case is compared with similar observations already studied in the literature. From an aetiological standpoint, attention is drawn to the apparent causative role of diuretic therapy which had resulted in severe water and electrolyte disturbances.
mesh_terms: D000328:Adult; D001539:Bendroflumethiazide / Q000506:poisoning*; D001927:Brain Diseases / Q000139:chemically induced* / Q000473:pathology; D003711:Demyelinating Diseases / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007049:Iatrogenic Disease; D008297:Male; D013577:Syndrome; D014883:Water-Electrolyte Imbalance / Q000139:chemically induced*
chemical_list: D001539:Bendroflumethiazide
vernacular_title: Myélinolyse centro-pontine associêe à des lêsions plus diffuses de la substance blanche. Troubles hydroêlectrolytiques en relation avec un traitement diurêtique