title: Synthesis of some quinoline derivatives of potential antiamebic activity.
abstract: New compounds derived from cinchoninic acid esters and amides were prepared. The esters are those derived from p-hydroxy-N-methyldichloroacetanilide (diloxanide) whereas the amides are from piperazine whose hydrogen is substituted by a dichloroacetyl group. The dichloroacetamido group is responsible for the amebicidal activity in several related compounds.
mesh_terms: D000563:Amebicides / Q000138:chemical synthesis; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000563:Amebicides; D011804:Quinolines