Temporal bone showing otosclerosis, paget's disease and adenocarcinoma.
In a pair of temporal bones serial sectioning revealed widespread Paget's disease with otosclerosis on both sides and, at the right side, adenocarcinoma added. Stapedial fixation was produced on the right by otosclerosis, and on the left by Paget's disease. In the contest to reach the inner cochlear space, Paget was the winner on the left, where, at the tympanic scala, otosclerosis and Paget's disease almost met, while the immediately adjacent organ o Corti was uninvolved.
D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D010001:Osteitis Deformans / Q000473:pathology*; D010026:Osteosclerosis / Q000473:pathology*; D012888:Skull Neoplasms / Q000473:pathology*; D013701:Temporal Bone / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000473:pathology