Ultrastructural observations on stumpy (stm), a new chondrodystrophic mutant in the mouse.
Stumpy (stm) is a new chondrodystrophic mutant in the mouse. Light microscopy of cartilage reveals a slightly increased mitotic rate, more chondrocytes than is usual per lacuna and a wide zone of hypertrophy. Electron microscopy shows that many chondrocytes are in close approximation with some tight junctions: in cartilage from 14-day-old mice there is much interdigitation and folding of the cell membranes of adjacent chondrocytes.
D000818:Animals; D002356:Cartilage / Q000002:abnormalities / Q000648:ultrastructure*; D002806:Chondrodysplasia Punctata / Q000473:pathology*; D051379:Mice; D008938:Mitosis; D009154:Mutation