[May Perthes' disease be due to venous block? Experimental investigations on growing pigs].
In 13 growing pigs (mini-pigs) all veins draining the head of femur were ligated intra-abdominally. In 2 i.v. injection of 12% Varigloban into the common iliac vein was added, in another 2 the same drug was injected into the head of femur. No real changes could be seen in X-rays, macro- and microscopically. Slides showed only more or less pronounced fibrosis. Scintigrams showed a reduction of radio-active storage in the head of femur by about 12%. The results and conclusions for human pathology are discussed.
D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D005270:Femur Head / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology; D007873:Legg-Calve-Perthes Disease / Q000209:etiology*; D008026:Ligation; D008297:Male; D008854:Microscopy, Electron; D010007:Osteochondritis / Q000209:etiology*; D011859:Radiography; D011877:Radionuclide Imaging; D013552:Swine; D014680:Veins
Gibt es einen Morbus Perthes durch venöse Stase? Experimentelle Untersuchungen am wachsenden Schwein.