Ethinylestradiol and dl-norgestrel as a postcoital contraceptive.
Six hundred and eight women were treated with 200 microgram of ethinylestradiol and 2 mg of dl-norgestrel, administered in two divided doses, as a postcoital contraceptive. Criteria for entry into the study included definite unprotected coital exposure within the previous 72 hours and the absence of any contraindications to the use of estrogen/progestin-containing compounds. Women with coital exposures outside of the 72-hours-to-treatment time frame were excluded. Four hundred and sixty-four of the patients were cycling regularly and, of these, 152 were exposed at midcycle. Only one patient became pregnant as a result of probable method failure as compared with the minimal estimated number of 12 to 30 pregnancies.
D000293:Adolescent; D000328:Adult; D003268:Contraception Behavior; D003281:Contraceptives, Postcoital / Q000494:pharmacology*; D004334:Drug Administration Schedule; D004997:Ethinyl Estradiol / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D005260:Female; D005306:Fertilization / Q000187:drug effects; D006801:Humans; D008598:Menstruation; D009325:Nausea / Q000139:chemically induced; D009644:Norgestrel / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D011247:Pregnancy; D013997:Time Factors
D003281:Contraceptives, Postcoital; D009644:Norgestrel; D004997:Ethinyl Estradiol