A family with dominantly inherited mild juvenile diabetes.
A family of 53 members is described in which mild diabetes in young, non-obese subjects is transmitted through four generations from parents to children, the ratio diabetic/non-diabetic offspring of diabetic parents being 3:2 and all affected individuals having a diabetic parent. In this family, mild juvenile diabetes thus appears to be inherited as an autosomal Mendelian dominant.
D000328:Adult; D000368:Aged; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics*; D005500:Follow-Up Studies; D005799:Genes, Dominant; D005951:Glucose Tolerance Test; D006801:Humans; D008875:Middle Aged; D010375:Pedigree