Radiation-induced bladder tumors.
A recent 25-year experience with patients treated for carcinoma of the uterine cervix who subsequently had bladder tumors is presented. Of the 3,091 patients treated 2,674 had received radiotherapy and 8 suffered vesical malignancies of varied histopathological type 6 months to 20 years after irradiation. This incidence rate is 299.9 per 100,000, which is 57.6 times that of the general female population. Benign radiation reactions of the bladder and the possible etiology of radiation-induced bladder cancers are discussed.
D000328:Adult; D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000209:etiology; D003037:Cobalt Radioisotopes / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011867:Radioisotope Teletherapy / Q000009:adverse effects*; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D001749:Urinary Bladder Neoplasms / Q000209:etiology*; D014594:Uterine Neoplasms / Q000532:radiotherapy*
D003037:Cobalt Radioisotopes