HLA antigens and susceptibility to atopic dermatitis.
The possible association between peculiar HLA antigens ant atopic dermatitis associated allergic rhinitis and/or bronchial asthma was investigated. (1) Atopic dermatitis (no deviation in HLA), complicating allergic rhinitis (HLA-BW40), and bronchial asthma (HLA-B12) are associated by different HLA antigens. (2) The diseases are associated through the same antigen (HLA-BW15), if the concept of disease resistant antigen is accepted. (3) No association is found between HLA antigens and serum IgE levels in patients.
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D005796:Genes; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006650:Histocompatibility Testing; D006801:Humans; D008297:Male; D010641:Phenotype; D006255:Rhinitis, Allergic, Seasonal / Q000235:genetics
D006680:HLA Antigens; D006649:Histocompatibility Antigens