Growth hormone: species-specific stimulation of erythropoiesis in vitro.
The effects of purifed bovine and human growth hormone were tested in vitro with murine and human bone marrow by means of granulocyte-monocyte and erythroid progenitor cloning techniques. Nanogram concentrations of the growth hormones potentiated erythropoietin-stimulated erythropoiesis, but not granulopoiesis, in a species-specific manner.
D000818:Animals; D001854:Bone Marrow Cells; D002417:Cattle; D004920:Erythropoiesis / Q000187:drug effects*; D004921:Erythropoietin / Q000494:pharmacology; D006098:Granulocytes / Q000166:cytology; D013006:Growth Hormone / Q000494:pharmacology*; D006410:Hematopoiesis / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D051379:Mice; D010455:Peptides / Q000494:pharmacology; D010928:Placental Lactogen / Q000494:pharmacology; D013045:Species Specificity; D013329:Structure-Activity Relationship; D013552:Swine
D010455:Peptides; D004921:Erythropoietin; D013006:Growth Hormone; D010928:Placental Lactogen