Aspergillus terreus osteomyelitis.
Aspergillus terreus infection limited to the L1-2 disk space and first and second lumbar vertebrae developed in a patient not predisposed to invasive aspergillosis. The observation of morphologically distinct secondary spores (aleuriospores) on microscopic examination of open biopsy specimens permitted a preliminary identification of A terreus, which was confirmed by culture. The infection was eradicated with amphotericin B in a total dose of 3 gm. Aspergillus terreus is usually a saprophyte. The present case and four others collected from the literature establish this species as an invasive pathogen.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000473:pathology; D001706:Biopsy; D005260:Female; D006801:Humans; D008161:Lumbosacral Region; D010019:Osteomyelitis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D013122:Spinal Diseases / Q000175:diagnosis* / Q000473:pathology; D019966:Substance-Related Disorders
D000666:Amphotericin B