title: Intravascular phagocytosis in the rabbit bone marrow: a possible fate of normal senescent red cells.
abstract: Perisinal macrophages in the rabbit bone marrow can penetrate the sinus wall and phagocytose circulating red cells intraluminally. Serial sectioning reveals that the penetration occurs through the cytoplasm of a single endothelial cell. This phenomenon may provide an effective mechanism for monitoring the circulation and removing normal senescent red cells.
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000648:ultrastructure; D004912:Erythrocytes; D008264:Macrophages / Q000502:physiology; D010587:Phagocytosis; D011817:Rabbits; D013997:Time Factors