Kidney structure and function of desert kangaroos.
The structure and function of the kidneys of two species of desert kangaroos, the red kangaroo (Megaleia rufa) and the euro (Macropus robustus), were examined. Both kangaroos had glomerular filtration rates (GFR), renal plasma flows, and urine flow rates, when hydrated and dehydrated, which were lower than those of similarly sized eutherian mammals. The differences observed between the two species of marsupials were both structural and functional. The GFR of the red kangaroo was higher than that of the euro, under hydrated and dehydrated conditions, and this was correlated with the occurrence of larger and more numerous glomeruli, particularly juxtamedullary glomeruli, in the red kangaroo. Although the kidney of the euro had a greater relative medullary thickness than that of the red kangaroo, the latter had better urine-concentrating abilities. As opposed to this the euros reabsorbed significantly more urea from the filtrate when dehydrated (89.0%) than did the red kangaroos (69.2%). This ability of the euro to resorb more urea may be related to their tendency to overgraze their restricted home ranges during drought.
D000818:Animals; D003681:Dehydration / Q000503:physiopathology; D003889:Desert Climate; D004231:Diuresis; D005260:Female; D005919:Glomerular Filtration Rate; D007668:Kidney / Q000033:anatomy & histology* / Q000502:physiology*; D007684:Kidney Tubules / Q000378:metabolism; D007614:Macropodidae / Q000033:anatomy & histology / Q000502:physiology; D008297:Male; D008394:Marsupialia / Q000033:anatomy & histology; D009994:Osmolar Concentration; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D013045:Species Specificity; D014508:Urea / Q000378:metabolism
D014508:Urea; D012964:Sodium; D011188:Potassium