Computerized tomography of ischemic myocardium: quantitation of extent and severity of edema in an in vitro canine model.
The capacity of computerized tomography to assess myocardial edema resulting from acute coronary occlusion was investigated in 19 arrested and 2 beating canine hearts. Edematous myocardium was consistently detected as areas of decreased attenuation values. The magnitude of the decrease in attenuation value was linearly related to the severity of the edema. The anatomic definition and tomographic information in the arrested hearts provided the capability for localization and quantitation of the extent of the lesion. The results of these in vitro investigations indicate that CT scanning is a technique which will contribute important pathophysiologic information about the evolution of myocardial ischemia.
D000818:Animals; D003327:Coronary Disease / Q000150:complications* / Q000000981:diagnostic imaging; D004285:Dogs; D004489:Edema, Cardiac / Q000000981:diagnostic imaging* / Q000209:etiology; D006333:Heart Failure / Q000000981:diagnostic imaging*; D066298:In Vitro Techniques; D014057:Tomography, X-Ray Computed