Phase separation of a protein-water mixture in cold cataract in the young rat lens.
A remarkable resemblance between the appearance of opacity in lysozyme--salt water mixtures and the development of opacity in cold cataract in the young rat lens is strong evidence that cold cataract is fundamentally a phase separation of the "protein-water binary mixture" in the lens.
D000818:Animals; D002386:Cataract / Q000209:etiology*; D003459:Crystallins; D007908:Lens, Crystalline; D008954:Models, Biological; D009113:Muramidase; D051381:Rats; D012965:Sodium Chloride; D012996:Solutions; D013816:Thermodynamics
D003459:Crystallins; D012996:Solutions; D012965:Sodium Chloride; D009113:Muramidase