title: Determination of protein synthesis elongation factor activity in liver biopsy specimens from normal and cirrhotic rats.
abstract: In liver biopsy specimens (between 8.5 and 22 mg wet weight) obtained from normal and thioacetamide-induced cirrhotic rat liver the polypeptide-chain-elongationpromoting activity (elongation factors 1 and 2) was determined. In liver cirrhosis the activity is reduced by about 50%.
mesh_terms: D000818:Animals; D001706:Biopsy; D004247:DNA / Q000032:analysis; D008099:Liver / Q000378:metabolism* / Q000473:pathology; D008103:Liver Cirrhosis / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D010445:Peptide Elongation Factors / Q000032:analysis; D010649:Phenylalanine / Q000096:biosynthesis; D014176:Protein Biosynthesis; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D010445:Peptide Elongation Factors; D010649:Phenylalanine; D004247:DNA