title: [Protein composition of human saliva under rest and stimulation and its changes in salivary gland diseases].
abstract: In 153 probands the following parameters of normal parotid gland secretion were examined: flow-rate, total protein excretion, lysozyme, amylase, phosphatase, BAEE-esterase, immunglobulin A and trypsin-inhibitor. The results were compared with secretions of parotid glands with tumors (51 patients), sialadenitis (22 patients) and sialadenosis (12 patients). Thereby differential diagnosis in sialotumors was found possible. The mose important parameters are flow-rate, protein and immunglobulin A-concentrations, Moreover it is possible to differentiate in sialadenitis and sialadenosis: lysocym secretion gives besides flow--rate protein and immunglobulin A-concentration a good parameter in differentiating both pathological findings. Discelectrophoretic and immunoelectrophoretic separations supplement the differential diagnosis in sialotumors, sialadenitis and sialadenosis. The results are discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D004589:Electrophoresis, Disc; D005260:Female; D006801:Humans; D007122:Immunoelectrophoresis; D007070:Immunoglobulin A / Q000302:isolation & purification; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000276:immunology / Q000378:metabolism; D010309:Parotitis / Q000276:immunology; D012463:Saliva / Q000378:metabolism*; D012466:Salivary Gland Diseases / Q000378:metabolism*; D012471:Salivary Proteins and Peptides / Q000378:metabolism*; D012793:Sialadenitis / Q000276:immunology / Q000378:metabolism
chemical_list: D007070:Immunoglobulin A; D012471:Salivary Proteins and Peptides
vernacular_title: Zur Protein-Zusammensetung des menschlichen Aarotissekretes unter Ruhe- und Reizbedingungen und seine Veränderung bei Drüsenerkrankungen.