The natural history of non-disciform ocular histoplasmosis.
Nineteen of 21 asymptomatic individuals with non-disciform atrophic chorioretinal scars characteristics of the ocular histoplasmosis syndrome and identified in the Walkersville survey were re-examined three years later. During this period, of six subjects with peripapillary scars, one developed symptomatic serous detachment of the peripapillary retina; none of the three with macular or paramacular scars showed any change. Several peripheral scars showed increased pigmentation and others definite enlargement. One patient developed two new atrophic scars.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001284:Atrophy; D002829:Choroid; D002921:Cicatrix; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006660:Histoplasmosis / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D008266:Macula Lutea; D008297:Male; D008396:Maryland; D008875:Middle Aged; D009898:Optic Disk; D011379:Prognosis; D012163:Retinal Detachment / Q000453:epidemiology / Q000209:etiology; D014603:Uveal Diseases / Q000209:etiology; D044465:White People