Amino acids and derivatives of thiazole-4-carboxylic acid as constituents of thiopeptin B.
L-Alanine, L-threonine, L-valine, D-cystine and three derivatives of thiazole-4-carboxylic acid (thiostreptin, 1-aminomethylthiazole-4-carboxylic acid and thiostreptoic acid) were isolated from the acid-hydrolysate of thiopeptin B. In addition, the presence of dehydrobutyrine and dehydroalanine residues in the antibiotic was determined. Other components remain unidentified.
D000596:Amino Acids / Q000032:analysis*; D000900:Anti-Bacterial Agents / Q000032:analysis*; D023181:Antimicrobial Cationic Peptides; D002264:Carboxylic Acids / Q000032:analysis; D006868:Hydrolysis; D010455:Peptides / Q000032:analysis; D013844:Thiazoles / Q000032:analysis*
D000596:Amino Acids; D000900:Anti-Bacterial Agents; D023181:Antimicrobial Cationic Peptides; D002264:Carboxylic Acids; D010455:Peptides; D013844:Thiazoles; C003453:thiopeptin B