Intrathecal Rubella and RNA antibody synthesis in multiple sclerosis and progressive rubella panencephalitis.
The assay of serum and CSF rubella and RNA antibodies in 3 patients (2 multiple sclerosis and 1 progressive rubella panencephalitis) shows their predominant local (intrathecal) syntheses. This correlation suggests that RNA antibodies may be directed against the viral genome itself.
D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000032:analysis / Q000134:cerebrospinal fluid*; D000914:Antibodies, Viral / Q000032:analysis / Q000134:cerebrospinal fluid; D004247:DNA / Q000276:immunology; D004660:Encephalitis / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D008297:Male; D009103:Multiple Sclerosis / Q000276:immunology*; D012313:RNA / Q000276:immunology*; D012409:Rubella / Q000276:immunology*; D012412:Rubella virus / Q000276:immunology*
D000906:Antibodies; D000914:Antibodies, Viral; D007074:Immunoglobulin G; D012313:RNA; D004247:DNA