Relation between HLA-B27 and clinical features in patients with yersinia arthritis.
A study of 74 yersinia arthritis patients implied that the clinical picture of the disease may be modified by genetic background associated with the histocompatibility antigen B27 (HLA-B27). Sixty-six percent of patients were B27 positive. Joint symptoms were somewhat more severe in B27+ patients. Iritis, conjunctivitis, carditis, signs of urologic inflammation, and complete Reiter's triad occurred only in the B27 + group, whereas erythema nodosum was more common in B27 - group. Several B27 + patients also had "B27 + rheumatic diseases," such as ankylosing spondylitis or Reiter's disease, in their history.
D000328:Adult; D001170:Arthritis, Infectious / Q000235:genetics / Q000276:immunology* / Q000473:pathology; D003718:Denmark; D005260:Female; D005387:Finland; D006680:HLA Antigens / Q000032:analysis*; D006649:Histocompatibility Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D015009:Yersinia Infections / Q000235:genetics / Q000276:immunology* / Q000473:pathology
D006680:HLA Antigens; D006649:Histocompatibility Antigens