Organic acidosis in infants.
Any child or adult who has persistent acidosis after apparently adequate treatment should be suspected of having an organic aciduria, as should any person with a large anion gap and acidosis. The possibility that some can presently be treated, makes early diagnosis urgent. Acidosis occurs in hypoperfused states, and treatment of the hypoperfusion with half- to two-thirds-strength of physiological saline with 40 mEq/1 of potassium may correct the acidosis without there being any need to use bicarbonate.
D000138:Acidosis / Q000188:drug therapy / Q000209:etiology; D000328:Adult; D002648:Child; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000188:drug therapy; D007773:Lactates / Q000097:blood; D008764:Methylmalonic Acid / Q000097:blood; D011422:Propionates / Q000097:blood; D011773:Pyruvates / Q000097:blood; D014631:Valerates / Q000097:blood
D007773:Lactates; D011422:Propionates; D011773:Pyruvates; D014631:Valerates; D008764:Methylmalonic Acid