Synthesis and characterization of glucuronides of Cannabinol, cannabidiol, delta9-tetrahydrocannabinol and delta8-tetrahydrocannabinol.
Partially purified glucuronyltransferase immobilized on beaded sepharose has been used to synthesize the glucuronide conjugates of cannabinol, cannabidol, delta9-tetrahydrocannabinol and delta8-tetrahydrocannabinol. Trimethylsilylated methyl esters and per(trimethylsilyl) derivatives of these conjugates have been characterized by their gas chromatographic retention times and their electron impact and ammonia chemical ionization mass spectra.
D002185:Cannabidiol / Q000031:analogs & derivatives / Q000138:chemical synthesis; D002186:Cannabinoids / Q000138:chemical synthesis; D002187:Cannabinol / Q000031:analogs & derivatives / Q000138:chemical synthesis; D055598:Chemical Phenomena; D002621:Chemistry; D002849:Chromatography, Gas / Q000379:methods; D013759:Dronabinol / Q000031:analogs & derivatives / Q000032:analysis / Q000138:chemical synthesis; D005965:Glucuronates / Q000138:chemical synthesis; D013058:Mass Spectrometry / Q000379:methods
D002186:Cannabinoids; D005965:Glucuronates; D002185:Cannabidiol; D013759:Dronabinol; D002187:Cannabinol