Nutritional influences of pellagra on sebum composition.
Sebum composition has been measured in 51 patients with varying degrees of pellagra and compared with a control group of subjects in the same geographic area. In the pellagra group the wax ester percentage was 14-9 versus the normal of 21-9%. The squalene percentage was increased in the pellagra group (11-6%) versus a control value of 8-4%. A small increase in the percentage of cholesterol was also noted. These changes, which previously have been observed in starved but otherwise normal subjects, were reversible with adequate refeeding.
D000328:Adult; D002784:Cholesterol / Q000032:analysis; D005227:Fatty Acids / Q000032:analysis; D006801:Humans; D008875:Middle Aged; D010383:Pellagra / Q000378:metabolism*; D012629:Sebum / Q000032:analysis*; D013185:Squalene / Q000032:analysis; D013997:Time Factors; D014885:Waxes / Q000032:analysis
D005227:Fatty Acids; D014885:Waxes; D013185:Squalene; D002784:Cholesterol