The natural history of senile retinoschisis.
The natural history of senile retinoschisis was studied in 193 eyes of 108 non-referred patients while refraining from the use of any prophylactic intervention, over follow-up periods ranging from 2 to 11 years. No case of clinical symptomatic retinal detachment occurred. 2 cases of small localized subclinical retinal detachment  occurred, but these did not progress. 9 eyes showed new retinal holes. 11 showed increase in extent, and 7 showed spontaneous regression of lesions. An estimated risk of clinical detachment is calculated and four indications for treatment are given.
D000328:Adult; D000368:Aged; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D012160:Retina / Q000473:pathology; D012162:Retinal Degeneration / Q000150:complications / Q000473:pathology*; D012163:Retinal Detachment / Q000209:etiology