Light evoked release of radioactivity from rabbit retinas preloaded with (3H)-GABA.
Light flashes evoke an increased release of radioactivity in vitro from rabbit retinas preloaded with (3H)-GABA in vivo. Constant light does not affect the release. No light evoked release can be demonstrated from the glia. Pentobarbitone and AOAA depress the evoked release. The results are consistent with GABA being a retinal neuro-transmitter, most likely in a class of amacrines.
D000613:Aminobutyrates / Q000378:metabolism*; D000818:Animals; D007700:Kinetics; D008027:Light; D010477:Perfusion; D011817:Rabbits; D012160:Retina / Q000378:metabolism*; D013997:Time Factors; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D000613:Aminobutyrates; D005680:gamma-Aminobutyric Acid