Enzymatic mechanism of benzo[a]pyrene conversion to phenols and diols and an improved high-pressure liquid chromatographic separation of benzo[a]pyrene derivatives.
D000818:Animals; D001580:Benzopyrenes / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004851:Epoxide Hydrolases / Q000378:metabolism*; D006836:Hydro-Lyases / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D010088:Oxidoreductases / Q000378:metabolism*; D010103:Oxygen Isotopes; D010636:Phenols / Q000302:isolation & purification*; D051381:Rats; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism
D001580:Benzopyrenes; D010103:Oxygen Isotopes; D010636:Phenols; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D004851:Epoxide Hydrolases; D006836:Hydro-Lyases