Transient neutropenia in a patient receiving cimetidine.
Transient neutropenia developed in a 62-year-old, white male on maintenance hemodialysis being treated with cimetidine for an in tractable duodenal ulcer. The probable mechanism was peripheral destruction of the granulocyte series, unlike the marrow depression reported with metiamide, another histamine H2 receptor antagonist.
D000380:Agranulocytosis / Q000139:chemically induced*; D000897:Anti-Ulcer Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004381:Duodenal Ulcer / Q000188:drug therapy; D006146:Guanidines / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007093:Imidazoles / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000139:chemically induced*; D006435:Renal Dialysis
D000897:Anti-Ulcer Agents; D006146:Guanidines; D007093:Imidazoles