title: Safe amounts of contrast medium for angiocardiography in neonates and infants.
abstract: The results were analysed of 485 (biplane) cineangiocardiograms performed in 200 consecutive cardiac investigations on neonates (under 4 wk) and infants (4 wk to 1 yr). 10 deaths occurred during or within 24 h of cardiac catheterization, all in patients who were profoundly acidemic because of their hemodynamic disturbance. A total dose of Cardio-Conray at any one investigation of 4-5 ml/kg body weight was satisfactory and without undue risk. Single injections of 1.5-2.0 ml/kg body weight were safe whilst providing optimal diagnostic information. The interval between multiple injections did not appear to affect the risk to the patients.
mesh_terms: D000790:Angiocardiography; D006328:Cardiac Catheterization; D002932:Cineangiography; D003287:Contrast Media / Q000008:administration & dosage* / Q000009:adverse effects; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007267:Injections; D007482:Iothalamate Meglumine / Q000008:administration & dosage / Q000009:adverse effects; D007483:Iothalamic Acid / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D003287:Contrast Media; D007483:Iothalamic Acid; D007482:Iothalamate Meglumine