title: Subcellular reactions to injury. I. Ultrastructural and biochemical investigations on the hepatic cellular damage produced by haemorrhagic shock in dogs.
abstract: The ultrastructural changes produced by haemorrhagic shock in hepatocytes have been studied in dogs. The associated biochemical and biophysical system alterations allow us to propose a unitary pathogenetic mechanism of the cellular injury based on oxygen deprivation and its effect on the function and structure of the cellular compartments.
mesh_terms: D000818:Animals; D003593:Cytoplasm / Q000648:ultrastructure; D004285:Dogs; D004573:Electrolytes / Q000378:metabolism; D008099:Liver / Q000378:metabolism / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008930:Mitochondria, Liver / Q000648:ultrastructure; D010101:Oxygen Consumption; D012771:Shock, Hemorrhagic / Q000378:metabolism / Q000473:pathology*
chemical_list: D004573:Electrolytes