title: The fine structure of developing elastic cartilage.
abstract: The fine structure of the elastic cartilage of the pinna has been examined in young rabbits aged from 1 day to 1108 days. Changes associated with growth and development are related not only to age but also to the actual situation in the pinna. In the midline, progressive changes are seen from the tip to the base. The changes in the chondroblasts with time are compared with those described in hyaline cartilage. Structures occur that, except for the presence of crystals, are apparently morphologically identical with the matrix vesicles of calcifying cartilage. These matrix vesicles, however, become very prominent with age, and aggregations of them appear to be released into the intercellular tissue from vacuoles at the periphery of the chondroblasts. There is no obvious association with calcification. Occasional single cilia, desmosomes and giant mitochondria are seen. Elastica is present at birth, and eventually every cell is separated from its neighbours by a partial investment of elastica. The quantity of matrix seems to increase with time, and with distance from the tip of the ear. This is accompanied by a marked increase in cell size with time.
mesh_terms: D000367:Age Factors; D000818:Animals; D002356:Cartilage / Q000254:growth & development / Q000648:ultrastructure*; D003094:Collagen / Q000032:analysis; D003593:Cytoplasm / Q000648:ultrastructure; D004431:Ear, External; D004547:Elastic Tissue / Q000648:ultrastructure; D008854:Microscopy, Electron; D011817:Rabbits
chemical_list: D003094:Collagen