title: [Haemodynamic effects of dextran 6% in the treatment of haemorrhage (author's transl)].
abstract: An isovolaemic infusion of dextran 6% after 1000 ml haemorrhage produced an increase in blood volume. This response persisted over a 4 h period, during which time a marked increase of venous return, stroke volume and cardiac output was be demonstrated. Improvement in the central circulation was produced through a significant drop in total peripheral resistance. The administration of the plasma expander was associated with an acute renal hyperperfusion.
mesh_terms: D001794:Blood Pressure; D001810:Blood Volume; D002302:Cardiac Output; D002496:Central Venous Pressure; D003911:Dextrans / Q000494:pharmacology*; D006339:Heart Rate; D006439:Hemodynamics / Q000187:drug effects*; D006470:Hemorrhage / Q000628:therapy*; D006801:Humans; D007668:Kidney / Q000098:blood supply; D012039:Regional Blood Flow; D013997:Time Factors; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D003911:Dextrans
vernacular_title: Einfluss von makromolekularem Dextran auf die Hämodynamik des menschlichen Blutkreislaufes bei kontrollierter Hypovolämie.