[Effect of retinol deficiency on the activity of phospholipase A lysosomal enzymes in rat testes].
In the testes homogenates of rats kept on a A-deficient ration and receiving additionally retinyl-acetate (control) and retinoic acid (experiment) the activity of the phospholipases A1 and A2, with 1-acyl-2(1-14C)-oleoyl-SN-glycero-3-galactosidase and acid phosphatase employed as a substrate, was investigated. In the testes of rats receiving retinyl-acetate the activity of the phospholipases A1 and A2 was greatly declining. An addition of retinyl to the testes homogenates of test rats contributed to re-establishing the activity of the phospholipases up to the control level. In the testes of rats receiving retinoic acid a reduced activity of the acid phosphatase and a rise of beta-galactosidase, as compared to their activity in controls was also demonstrable.
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D004032:Diet; D004789:Enzyme Activation; D005696:Galactosidases / Q000378:metabolism; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D010740:Phospholipases / Q000378:metabolism*; D051381:Rats; D013091:Spermatogenesis; D013737:Testis / Q000201:enzymology*; D013997:Time Factors; D014212:Tretinoin / Q000008:administration & dosage; D014801:Vitamin A / Q000008:administration & dosage; D014802:Vitamin A Deficiency / Q000201:enzymology*
D014801:Vitamin A; D014212:Tretinoin; D010740:Phospholipases; D000135:Acid Phosphatase; D005696:Galactosidases
Vliianie nedostatochnosti retinola na aktivnost' fosfolipazy A i nekotorykh lizosomal'nykh fermentov v semennikakh krys.