Ovarian dysgenesis and chromosome abnormalities.
The association of ovarian hypoplasia with trisomy 18 in 6 infants and trisomy 13 in 5 infants and 1 fetus is reported. Three infants also had thymic hypoplasia. The possible etiology of ovarian dysgenesis is discussed in relation to a variety of clinical and experimental associations.
D000015:Abnormalities, Multiple / Q000175:diagnosis; D002901:Chromosomes, Human, 13-15; D002902:Chromosomes, Human, 16-18; D002904:Chromosomes, Human, 21-22 and Y; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010053:Ovary / Q000002:abnormalities* / Q000473:pathology; D014314:Trisomy; D014424:Turner Syndrome / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology