Metallic ions as negative modifiers of cholinesterase.
Copper and Zinc have been found to be potent inhibitors of pseudo-cholinesterase of human plasma and true-cholinesterase of erythrocytes and rat brain.
D000818:Animals; D001921:Brain / Q000201:enzymology; D002800:Cholinesterase Inhibitors; D002802:Cholinesterases / Q000097:blood; D003300:Copper / Q000494:pharmacology*; D004912:Erythrocytes / Q000201:enzymology; D006801:Humans; D066298:In Vitro Techniques; D051381:Rats; D015032:Zinc / Q000494:pharmacology*
D002800:Cholinesterase Inhibitors; D003300:Copper; D002802:Cholinesterases; D015032:Zinc