Hereditary vitelliform macular degeneration: variable fundus findings within a single pedigree.
A pedigree of 141 persons with hereditary vitelliform macular degeneration was studied. Of the 80 patients examined, 20 were affected. Fundus photographs of selected lesions in this pedigree demonstrated the broad spectrum of phenotypic expression of this hereditary disorder. This entity has an extremely variable expression even among affected members of the same family.
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008266:Macula Lutea / Q000473:pathology; D008268:Macular Degeneration / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012162:Retinal Degeneration / Q000235:genetics*