title: Psychotropic drugs and migraine.
abstract: The incidence and differential diagnosis of migraine is discussed. The use of clomipramine (Anafranil) in the prophylaxis of migraine is considered and the results of a pilot study presented. The problems which arise in the organization of clinical trials of migraine prophylaxis and hypotheses for the possible mode of action of clomipramine and other psychotropic drugs in the prevention of migraine are discussed.
mesh_terms: D000328:Adult; D002648:Child; D002997:Clomipramine / Q000494:pharmacology / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D003984:Dibenzazepines / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D010865:Pilot Projects; D012106:Research; D012701:Serotonin / Q000097:blood
chemical_list: D003984:Dibenzazepines; D012701:Serotonin; D002997:Clomipramine