title: Relation between stimulus intensity and neutrophil chemotactic response.
abstract: The effect of chemotactic peptides which lack chemokinetic activity has been investigated. The neutrophil response is proportional to the logarithm of the stimulus intensity, or alternatively a power function with an exponent of 0.3. Equal responses are obtained for equal ratios between the peptide concentration in the lower compartment and the threshold concentration. The significance of Weber-Fechner's law in leucocyte chemotaxis is discussed.
mesh_terms: D000706:Anaphylatoxins / Q000494:pharmacology; D000818:Animals; D002634:Chemotaxis, Leukocyte / Q000187:drug effects; D007700:Kinetics; D009504:Neutrophils / Q000187:drug effects / Q000502:physiology; D013552:Swine
chemical_list: D000706:Anaphylatoxins