Determination of hydralazine in tablets by gas chromatography.
A description is given of a gas chromatographic method for the determination of hydralizine in various tablet formulations based on the quantitative reaction of hydralazine with 2,4-pentanedione to yield 1-(3,5-dimethylpyrazole)phthalazine. The stable hydralazine derivative formed is extracted from aqueous solution and chromatographed resulting in a precise and specific determination of hydralazine which correlates well with the U.S.P. XIX titrimetric procedure.
D055598:Chemical Phenomena; D002621:Chemistry; D002849:Chromatography, Gas / Q000379:methods; D006830:Hydralazine / Q000032:analysis*; D013058:Mass Spectrometry; D013607:Tablets
D013607:Tablets; D006830:Hydralazine