title: Effect of volume expansion and veratrine on salt gland secretion in the goose.
abstract: The influence of acute intravascular volume expansion on salt gland secretion of conscious, adult geese was investigated. The intravenous administration of 5% dextran in Krebs-bicarbonate-Ringer solution in an amount equivalent to 30% of the estimated blood volume caused a transient but highly significant increase in salt gland secretion independent of changes in plasma osmolality or sodium concentration. Intravenous veratrine (60 microng) caused a similar increase in salt gland secretion only when administered after the volume load. Intravenous 5% NaCl always caused a prolonged and significant increase in salt gland secretion which was not potentiated by veratrine. Volume expansion and hypertonic saline caused a significant tachycardia while veratrine caused a significant bradycardia. It is concluded that a volume component may contribute to the initiation of salt gland secretion in the goose and that the peripheral receptor involved is most likely vascular in origin.
mesh_terms: D000818:Animals; D001810:Blood Volume; D005777:Geese / Q000097:blood / Q000502:physiology*; D006339:Heart Rate / Q000187:drug effects; D011188:Potassium / Q000097:blood; D012462:Saline Solution, Hypertonic / Q000494:pharmacology; D012491:Salt Gland / Q000378:metabolism*; D011984:Sensory Receptor Cells / Q000502:physiology; D012964:Sodium / Q000097:blood; D014702:Veratrine / Q000494:pharmacology*; D014882:Water-Electrolyte Balance
chemical_list: D012462:Saline Solution, Hypertonic; D012964:Sodium; D014702:Veratrine; D011188:Potassium