Effect and fate of intravenously administered porphobilin in rats.
In rats after i.v. porphobilin, blood pressure and pulse rate remained stable, the animals were calm and moved freely with no symptoms or signs of nervous effect. Porphobilin was rapidly excreted in the urine.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D008297:Male; D011166:Porphyrins; D011758:Pyrroles / Q000378:metabolism* / Q000494:pharmacology; D051381:Rats; D013997:Time Factors
D011166:Porphyrins; D011758:Pyrroles; C015477:porphobilin