title: Practical and experimental studies on the use of prostaglandins F2alpha in pigs.
abstract: The possible practical uses of F2alpha prostaglandins (two different experimental preparations) in pigs are discussed. It was shown that the intramuscular injection of 1-2 mg PGF2alpha (in the region behind the ear) could result in oestrus, ovulation and subsequent conception in a considerable number (78.3%) of virgin pigs with persistent clinical anoestrus (15-16 months old), the start of normal oestrous cycles in pigs 10-11 months old and also the early appearance of oestrous symptoms in pigs of prepuberal age (6-7 months). As the PGF2alpha treatment did not have any adverse effects on the composition and the normal growth of the piglets (except for a smaller litter size in the prepuberal gilts, probably due to age of the animals), while transitory side-effects only occurred exceptionally after treatment (slight excitement), the use of PGF2alpha is suggested for production of functional recovery in virgin gilts with apparent persistent clinical anoestrus, for the synchronization of oestrus in primiparous gilts on farms with no apparent reproductive disorders, and for the concentration of births also in pluriparous pigs past the 12th day of the normal oestrous cycle before injection, and for the induction of precocious oestrus and subsequent early conception in gilts of prepuberal age.
mesh_terms: D000780:Anestrus / Q000187:drug effects; D000818:Animals; D004973:Estrus Synchronization / Q000187:drug effects; D005260:Female; D005306:Fertilization; D010060:Ovulation / Q000187:drug effects; D011247:Pregnancy; D011460:Prostaglandins F / Q000494:pharmacology*; D013552:Swine / Q000502:physiology*
chemical_list: D011460:Prostaglandins F