Nephritis associated with a diphtheroid-infected cerebrospinal fluid shunt.
Hypocomplementemic proliferative glomerulonephritis occurred during diphtheroid infection of a ventricular decompression shunt for cerebrospinal fluid diversion (cerebrospinal fluid shunt) in a young man. Granular deposits of immunoglobulin M (IgM) and the third component of complement (C3) were found along the glomerular basement membrane. This report provides supportive evidence for immune complex-mediated glomerular injury due to diphtheroid infection in a cerebrospinal fluid shunt.
D000328:Adult; D000936:Antigen-Antibody Complex; D001485:Basement Membrane / Q000276:immunology; D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects*; D003176:Complement C3; D003354:Corynebacterium Infections / Q000276:immunology; D005921:Glomerulonephritis / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D006801:Humans; D007075:Immunoglobulin M; D008297:Male
D000936:Antigen-Antibody Complex; D003176:Complement C3; D007075:Immunoglobulin M