Reproductive function in stallions treated with cambendazole.
Twenty stallions were used to determine if the anthelmintic cambendazole affected seminal characteristics, spermatogenesis, concentration of testosterone in blood serum, or weights of the reproductive orgrans. With minor exceptions, significant differences were not found between values for 10 control and 10 stallions treated with a single oral dose (40 mg/kg body weight) of cambendazole. The treatment did not affect reproductive function and it was concluded that the drug should have no effect on the fertility of stallions.
D000818:Animals; D001562:Benzimidazoles / Q000494:pharmacology*; D002159:Cambendazole / Q000494:pharmacology*; D006736:Horses / Q000502:physiology*; D008297:Male; D009929:Organ Size / Q000187:drug effects; D012098:Reproduction / Q000187:drug effects*; D012661:Semen / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects; D013737:Testis / Q000033:anatomy & histology / Q000187:drug effects; D013739:Testosterone / Q000097:blood; D013997:Time Factors
D001562:Benzimidazoles; D002159:Cambendazole; D013739:Testosterone