Thymidine-dependent strain of Salmonella oslo selected by trimethoprim-sulfamethoxazole therapy.
A case report describing the isolation of a multiple-drug-resistant strain of Salmonella oslo from urine and stool specimens is presented. After ten days of trimethoprim-sulfamethoxazole therapy, a second strain of Salmonella oslo was isolated from another stool specimen. The second strain was determined to be a thymidine-requiring organism. The significance of this thymidine-requiring strain is described.
D000328:Adult; D003470:Culture Media; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D012480:Salmonella Infections / Q000188:drug therapy*; D013420:Sulfamethoxazole / Q000627:therapeutic use*; D013936:Thymidine; D014295:Trimethoprim / Q000627:therapeutic use*
D003470:Culture Media; D004338:Drug Combinations; D014295:Trimethoprim; D013420:Sulfamethoxazole; D013936:Thymidine