Effect of O-ethylrutoside on serum and hepatic lipids in acute ethanal-treated rats.
The serum total lipids, triglycerides, total cholesterol and free fatty acid concentrations, as well as hepatic triglyceride and cholesterol levels, were increased in acutely ethanol-treated rats. Treatment of ethanol-given animals with o-ethylrutoside resulted in a significant reduction in all examined fractions of serum lipids and in the hepatic total cholesterol level.
D000818:Animals; D002784:Cholesterol / Q000032:analysis / Q000097:blood; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006896:Hydroxyethylrutoside / Q000031:analogs & derivatives* / Q000494:pharmacology; D008055:Lipids / Q000097:blood*; D008099:Liver / Q000032:analysis / Q000378:metabolism*; D008297:Male; D051381:Rats; D012431:Rutin / Q000031:analogs & derivatives*; D014280:Triglycerides / Q000097:blood
D005230:Fatty Acids, Nonesterified; D006896:Hydroxyethylrutoside; D008055:Lipids; D014280:Triglycerides; D000431:Ethanol; D012431:Rutin; D002784:Cholesterol