title: [Mechanism of disorders of inhibition of electrogenesis in spinal alpha-motor neurons in experimental local botulin poisoning].
abstract: Disorders of postsynaptic inhibition and of the spinal cord alpha-motoneurons were studied in cats with experimental local botulinum intoxication. A significant decrease of the reciprocal, and, to a lesser extent, of polysynaptic inhibitory postsynaptic potential (IPSP) was noted. With the appearance of total paralysis of the muscles in the poisoned extremity there proved to be an even greater depression of the reciprocal and polysynaptic IPSP; however, they never disappeared or turned into depolarization potentials. Synaptic permeability of motor neurons as a rule decreased during the IPSP development, this indirectly indicating a reduction of ion transport.
mesh_terms: D000818:Animals; D001905:Botulinum Toxins / Q000506:poisoning*; D002415:Cats; D008564:Membrane Potentials; D009046:Motor Neurons; D009433:Neural Inhibition; D013116:Spinal Cord / Q000503:physiopathology*; D013570:Synaptic Membranes / Q000502:physiology
chemical_list: D001905:Botulinum Toxins
vernacular_title: Mekhanizm narusheniia tormoznogo élektrogeneza v spinal'nykh alpha-motoneĭronakh pri éksperimental'noĭ mestnoĭ botulinicheskoĭ intoksikatsii.