[Change in rheographic properties of blood in congestive circulatory insufficiency treated with diuretics].
Proceeding from a dynamic study of the rheological properties of blood in 85 patients with stage II-III congestive circulatory insufficiency treated with diuretics (Furosemid, Hypothiazid, Uregit, Verospiron) a conclusion is made that a rational employment of diuretic agents does not result in any increase in blood concentration, and does not increase the risk of thrombotic complications. On the contrary, in some patients with stage IIB-III circulatory insufficiency some normalization of the rheological properties of blood, that had been impaired before the treatment, was noted. The use of diuretics only moderately increased the hematocrit and blood viscosity values, but decreased the aggregation of the erythrocytes and platelets. The improvement of the rheological properties of blood was attributed to the normalization of the water-electrolyte disorders that the patients had had. In cases in which thrombotic complications occurred a low hematocrit and blood viscosity level was common, while the erythrocytes and platelets aggregation was increased.
D000328:Adult; D000368:Aged; D001775:Blood Circulation; D001809:Blood Viscosity; D004232:Diuretics / Q000627:therapeutic use*; D004903:Erythrocyte Aggregation; D004976:Ethacrynic Acid / Q000627:therapeutic use; D005260:Female; D006333:Heart Failure / Q000097:blood* / Q000188:drug therapy / Q000503:physiopathology; D006400:Hematocrit; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation; D010992:Plethysmography, Impedance; D013148:Spironolactone / Q000627:therapeutic use
D004232:Diuretics; D006852:Hydrochlorothiazide; D013148:Spironolactone; D004976:Ethacrynic Acid
Izmenenie reologicheskikh svoĭstv krovi u bol'nykh s zastoĭnoĭ nedostatochnost'iu krovoobrashcheniia pri lechenii diuretikami.