[Fractional composition and methylation of liver cell nucleus histones during the early stages of radiation injury].
The radiation injury affects the quantitative ratio of histone fractions. The most pronounced changes in the percentage content towards a decrease are observed for the fractions F2a1 and F2a2 as well as for F2a 12 h and 24 h after irradiation, respectively. An increase by 41.8% is observed in the content of the fractions F2b+F3 12 h after irradiation. The methylation for all histones of the fractions increases considerably 2 h after irradiation, drops 12 h later in the fractions F2a1 and F3 and 24 h later in the fractions F3 and F1 as compared to the normal level.
D000818:Animals; D002467:Cell Nucleus / Q000528:radiation effects; D055598:Chemical Phenomena; D002621:Chemistry; D006657:Histones / Q000378:metabolism / Q000528:radiation effects*; D008099:Liver / Q000528:radiation effects*; D008745:Methylation; D011833:Radiation Injuries, Experimental / Q000378:metabolism*; D051381:Rats; D014965:X-Rays
D006657:Histones
Fraktsiĭnyĭ sklad ta metyliuvannia histoniv iader klityn pechinky na rannikh etapakh promenevoho urazhennia