Partial trisomy of chromosome 15.
Chromosome analysis of a moderately mentally retarded female revealed a 47,XX,+G? karyotype. Giemsa-trypsin banding showed the extra chromosome to be a deleted chromosome 15 (47,XX,+15q-). This case points out the importance of cytogenetic studies in moderately retarded individuals without significant physical anomalies.
D002648:Child; D002901:Chromosomes, Human, 13-15; D005260:Female; D006801:Humans; D006948:Hyperkinesis / Q000235:genetics; D008607:Intellectual Disability / Q000235:genetics*; D007621:Karyotyping; D013285:Strabismus / Q000235:genetics; D014314:Trisomy