Changes in gentamicin pharmacokinetics after reduction of renal parenchyma.
The relationship between the elimination constant of gentamicin and the percentage of functioning nephrons in rats cannot be characterized by a simple linear relation. The results support the assumption that gentamicin elimination per residual nephron increased.
D000818:Animals; D005260:Female; D005839:Gentamicins / Q000652:urine*; D007668:Kidney / Q000502:physiology*; D009392:Nephrectomy; D051381:Rats
D005839:Gentamicins