Cytotoxic agents from Bursera klugii (Burseraceae) I: isolation of sapelins A and B.
A crude chloroform-soluble fraction of the ethanol extract of the leaves of Bursera klugii showed activity against two test systems, the P-388 lymphocytic leukemia (3PS) and the human epidermoid carcinoma of the nasopharynx (9KB). The PS activity was due to two constituents, sapelins A and B.
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy; D006801:Humans; D007942:Leukemia, Experimental / Q000188:drug therapy; D009374:Neoplasms, Experimental / Q000188:drug therapy; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000032:analysis*; D014315:Triterpenes / Q000302:isolation & purification* / Q000627:therapeutic use
D000972:Antineoplastic Agents, Phytogenic; D014315:Triterpenes