title: [Rubella immunization--immunity after 4 years (author's transl)].
abstract: The rubella antibody titres were evaluated in 158 girls who had been seronegative prior to immunization and had been immunised 4 years previously (1971) with the rubella vaccine HPV77DE5. In 138 girls (87%) the 1975 titres were unchanged in comparison with 1971. Only in 5 girls (3.2%) the titres had decreased by up to 2 log2 steps. In two patients the titre reached the critical value of 1:8 which must be considered negative due to the high sensitivity of the haemagglutination inhibition test. A titre increase by two or more steps was observed in 15 girls (9.5%). A third of the titre increases might be due to reinfection with rubella wild virus which would correspond to a reinfection rate of less than 1% per year. Present knowledge indicates that reinfection during pregnancy does not endanger the unborn child.
mesh_terms: D000293:Adolescent; D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007109:Immunity; D012409:Rubella / Q000517:prevention & control*; D012411:Rubella Vaccine / Q000008:administration & dosage*; D013997:Time Factors; D014611:Vaccination
chemical_list: D000914:Antibodies, Viral; D012411:Rubella Vaccine
vernacular_title: Rötelnimpfung. Untersuchungen zum Immunstatus 4 Jahre nach Impfung mit dem Röteln-Impfstoff HPV77DE5.