[Effect of aminazine on the concentration of bound calcium in grape snail neurons].
By cytospectrophotometry it was shown that with the increase of chlorpromazine concentration in the external medium [CPZ]0 equal to 1-10(-8) M the concentration of bound calcium in the nuclei of neurons of Helix pomatia decreased, and at 3.2-10(-7) M chlorpromazine the Ca-concentration reduced to its minimum. A further increase in [CPZ]0 gradually increased the concentration of bound calcium, and at 1-10(-5) M chlorpromazine the concentration reached its maximum. An increase in [CPZ]0 from 1-10(-5) M to 1-10(-3) M caused a secondary decrease in the concentration of intranuclear calcium. A similar dependence was noticed for calcium bound by the cytoplasm of these cells.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002746:Chlorpromazine / Q000494:pharmacology*; D006372:Helix, Snails; D009474:Neurons / Q000187:drug effects*; D012908:Snails; D013053:Spectrophotometry
D002118:Calcium; D002746:Chlorpromazine
Vliianie aminazina na kontsentratsiir sviazannogo kal'tsiia v neĭronakh vinogradnykh ulitok.