title: Toxicological problems associated with the manufacture of triazapentadienes.
abstract: 1, 3, 5-triazapenta-1, 4-dienes are a new group of pesticides which are particularly effective against acarids. This report concerns various toxicological manifestations which occurred amongst the workforce of a small chemical processing plant engaged in the manufacturer of these substances. The toxic effects noted can be divided into three groups: (1) "Skin flushes", similar to those which have been observed amongst workers using dimethyl formamide. (2) Acute keratoconjunctivitis which occurred as a delayed reaction (between 6 and 12 hours after finishing work). (3) Intoxication following inhalation of isopropyl alcohol fumes. This is of special interest as reputable authorities discount this method of absorption as being a serious problem resulting from the use of isopropyl alcohol in an industrial situation.
mesh_terms: D000433:1-Propanol / Q000009:adverse effects*; D000435:Alcoholic Intoxication / Q000139:chemically induced; D000466:Alkadienes / Q000528:radiation effects*; D002617:Chemical Industry; D004126:Dimethylformamide / Q000009:adverse effects*; D004890:Erythema / Q000139:chemically induced; D006801:Humans; D007306:Insecticides / Q000009:adverse effects*; D007637:Keratoconjunctivitis / Q000139:chemically induced; D008297:Male; D011073:Polyamines / Q000009:adverse effects*
chemical_list: D000466:Alkadienes; D007306:Insecticides; D011073:Polyamines; D004126:Dimethylformamide; D000433:1-Propanol