[Indications for the monitoring of aminoglycoside serum concentrations in internal medicine (author's transl)].
Numerous factors in the human body can influence and cause variations in the pharmacokinetics of aminoglycoside antibiotics. As a result of these observations it has been demanded that all treatments with aminoglycosides be monitored. This would only appear to be justified for a limited number of indications, however, which involve very high dosages, long-term therapy and impaired renal function. The advantages of monitoring treatment are demonstrated in a patient with endocarditis.
D000328:Adult; D000617:Aminoglycosides / Q000097:blood*; D004697:Endocarditis, Bacterial / Q000097:blood / Q000188:drug therapy*; D005839:Gentamicins / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use; D006801:Humans; D008297:Male
D000617:Aminoglycosides; D005839:Gentamicins
Indikationen für Aminoglykosid-Serumkontrollen in der Inneren Medizin.