The effect of methotrexate on the uptake of de novo and salvage precursors into the DNA of rat tumours and normal tissues.
D000818:Animals; D001853:Bone Marrow / Q000378:metabolism; D002470:Cell Survival / Q000187:drug effects; D004247:DNA / Q000096:biosynthesis*; D004273:DNA, Neoplasm / Q000378:metabolism*; D005260:Female; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism; D007680:Kidney Neoplasms / Q000378:metabolism; D008727:Methotrexate / Q000494:pharmacology*; D009374:Neoplasms, Experimental / Q000378:metabolism; D009694:Nucleic Acid Precursors / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000378:metabolism; D013938:Thymidine Monophosphate / Q000378:metabolism
D004273:DNA, Neoplasm; D009694:Nucleic Acid Precursors; D013938:Thymidine Monophosphate; D004247:DNA; D008727:Methotrexate