Distribution of 14C after topical application of 14C-labeled 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) in mice.
Following topical application of 14C-labeled 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU, carmustine) to the skin of mice radioactivity was found in all viscera and tissues examined. Exclusive of the gut, highest values were recorded for the liver, kidney and lung.
D000287:Administration, Topical; D000818:Animals; D002330:Carmustine / Q000008:administration & dosage / Q000378:metabolism*; D005260:Female; D007413:Intestinal Mucosa / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D051379:Mice
D002330:Carmustine