Effect of dialysate calcium concentration on plasma parathyroid hormone during hemodialysis.
The effect of changes in the dialysate calcium concentration on calcium fractions and parathyroid hormone species in plasma during hemodialysis has been examined. C-terminal immunoreactive parathyroid hormone was suppressed when plasma calcium increased by greater than 25% whereas N-terminal fragments demonstrated an increase. The significance of this is discussed in light of present knowledge of parathyroid hormone metabolism.
D000328:Adult; D001798:Blood Proteins / Q000032:analysis; D002118:Calcium / Q000097:blood / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood*; D010710:Phosphates / Q000097:blood; D006435:Renal Dialysis
D001798:Blood Proteins; D010281:Parathyroid Hormone; D010710:Phosphates; D002118:Calcium