Use of a modified thromboelastograph to evaluate effects of acetylcysteine on sputum.
This work deals with a modification of a thromboelastograph which enables to measure both in vitro and in vivo effectiveness of mucolytic substances. A simple method is described for building up a comparative diagram of the effectiveness of several drugs; a diagram which is of interest from both a pharmacological and a clinical point of view.
D000111:Acetylcysteine / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D013183:Sputum / Q000187:drug effects*; D013916:Thrombelastography / Q000295:instrumentation*
D000111:Acetylcysteine