Three heritable responses to alcohol in a heterogeneous randomly mated mouse strain. Inferences for humans.
Alcohol-induced heart-rate change, open-field activity changes and sleeping time were found to be significantly heritable in mice. Heart rate and sleeping time may have parallels in man and mouse in their alcohol responses and genetics.
D000818:Animals; D001259:Ataxia / Q000139:chemically induced; D001831:Body Temperature / Q000187:drug effects; D004195:Disease Models, Animal; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D005824:Genetics, Behavioral; D006339:Heart Rate / Q000187:drug effects; D007178:Inbreeding; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D010641:Phenotype; D012890:Sleep / Q000187:drug effects; D013045:Species Specificity
D000431:Ethanol