Is the renal vasodilatation induced by beta-adrenoceptor stimulants in the dog mediated through dopamine receptor?
In chloralose-anaesthetized dogs the renal vasodilator effect of isoprenaline is depressed by blockade of either dopamine or beta-adrenoceptors but the renal vasodilator effect of dopamine is depressed only by blockade of dopamine receptors. This suggests that the vasodilatation induced by beta-stimulants within the canine kidney is due in part to activation of dopamine receptors.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D001842:Bone and Bones / Q000098:blood supply / Q000187:drug effects; D004285:Dogs; D004874:Ergonovine / Q000494:pharmacology*; D005260:Female; D007545:Isoproterenol / Q000494:pharmacology*; D007668:Kidney / Q000098:blood supply / Q000187:drug effects; D008297:Male; D011433:Propranolol / Q000494:pharmacology*; D011954:Receptors, Dopamine / Q000187:drug effects*; D012039:Regional Blood Flow / Q000187:drug effects*
D011954:Receptors, Dopamine; D011433:Propranolol; D007545:Isoproterenol; D000109:Acetylcholine; D004874:Ergonovine