[Effect of intravenous administration of spasmaverine on uterine activity during labor].
The authors have studied the action of an intravenous injection of Spasmaverine (Bis gamma phenyl-3-propylethylamine) on the intra-uterine pressure in labour in 20 cases. This study has shown that there is a definite rise in amplitude, in the frequency of contractions, in the uterine activity as expressed in montevideo units and in the basal tone of the uterus in the ten minutes following an injection of 80 mg of Spasmavérine intravenously. The fetal cardiac rhythm was never altered. The authors recommend care in using this substance intravenously when sedation of uterine activity is sought.
D005021:Ethylamines / Q000008:administration & dosage / Q000494:pharmacology; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007743:Labor, Obstetric / Q000187:drug effects*; D009129:Muscle Tonus / Q000187:drug effects; D010276:Parasympatholytics / Q000008:administration & dosage / Q000494:pharmacology*; D011247:Pregnancy; D011312:Pressure; D011437:Propylamines / Q000494:pharmacology*; D014590:Uterine Contraction / Q000187:drug effects*; D014599:Uterus / Q000187:drug effects* / Q000502:physiology
D005021:Ethylamines; D010276:Parasympatholytics; D011437:Propylamines
Effets de l'administration intraveineuse de spasmavérine sur l'activité utérine au cours du travail.