Staging laparotomy for Hodgkin's disease in children. Evaluation of the technique.
The evaluation of a technique of laparotomy for the staging of Hodgkin's disease in childhood, including 52 operative procedures, is reviewed. A standard protocol, including splenectomy, multiple hepatic and bone marrow biopsies, and the routine sampling of at least six designated lymph node groups, was employed. It was demonstrated that the surgeon is unable to identify Hodgkin's disease by gross inspection and that the biopsy of node groups previously not included in routine laparotomy studies, ie, mesenteric and porta hepatis nodes is essential to staging in childhood. Stage was altered from stages I and II to stages III and IV in 35% of the patients. The incidence of abdominal recurrence following a negative laparotomy was 7%, and the incidence of post-splenectomy hyperacute infection was 4.5%. This study included minimal use of the lymphangiogram (33%), which accounted for the relatively larger group of patients in clinical stages I and II.
D001706:Biopsy; D001856:Bone Marrow Examination; D002648:Child; D005069:Evaluation Studies as Topic; D005260:Female; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D007813:Laparotomy / Q000009:adverse effects; D008099:Liver / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D013154:Spleen / Q000473:pathology*; D013156:Splenectomy