Non-epithelial uterine tumours induced in CBA mice by 1,2-dimethylhydrazine.
In CBA mice treated with weekly subcutaneous injections of 1,2-dimethylhydrazine an unusually high incidence of uterine sarcomas was observed in two successive experiments. The tumours are easily transplantable. The description of their histological structure is presented and their histogenesis is discussed.
D000818:Animals; D004127:Dimethylhydrazines / Q000008:administration & dosage / Q000633:toxicity*; D005260:Female; D006834:Hydrazines / Q000633:toxicity*; D007279:Injections, Subcutaneous; D051379:Mice; D008808:Mice, Inbred CBA; D009368:Neoplasm Transplantation; D009442:Neurilemmoma / Q000139:chemically induced / Q000473:pathology; D012513:Sarcoma, Experimental / Q000139:chemically induced* / Q000473:pathology; D014185:Transplantation, Isogeneic; D014594:Uterine Neoplasms / Q000139:chemically induced* / Q000473:pathology
D004127:Dimethylhydrazines; D006834:Hydrazines