Delayed-type skin reactions in bursectomized or thymectomized chickens.
Chickens can easily be induced to develop delayed-type skin reactions to oxazolone when animals are sensitized 7 days before the challenge. The reaction is quantitated by assessing the increase in wattle thickness: maximum reactions occur 24 h after challenge. The reaction is inhibited by neonatal thymectomy or bursectomy; these findings therefore suggest also an important B-derived component in delayed hypersensitivity to oxazolone.
D000818:Animals; D002060:Bursa of Fabricius / Q000276:immunology*; D002645:Chickens; D003877:Dermatitis, Contact; D004342:Drug Hypersensitivity; D006968:Hypersensitivity, Delayed; D008297:Male; D010081:Oxazolone; D013950:Thymus Gland / Q000276:immunology*
D010081:Oxazolone