HLA and ragweed allergy.
In summary, two large families were subjected to genetic analysis of the distribution of the immune response. S linkage analysis indicated that this locus for positive skin test reaction to antigen E and/or personal history or seasonal allergy is linked to HLA-B. The maximum likelihood estimate of the recombination frequency is 0.13 in males and 0.53 in females, with a lod score of 2.53.
D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D005787:Gene Frequency; D005796:Genes; D008040:Genetic Linkage; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006801:Humans; D008297:Male; D010375:Pedigree; D011058:Pollen; D011995:Recombination, Genetic; D006255:Rhinitis, Allergic, Seasonal / Q000235:genetics*
D006680:HLA Antigens; D006649:Histocompatibility Antigens