Map order of the linkage group GLO-Bf-HLA-A-PGM3 on human chromosome 6.
Linkage analysis of 52 families with 181 children confirms close linkage for GLO-Bf, GLO-HLA-A, and Bf-HLA-A and proves linkage between HLA-A and PGM3. Linkage for Bf-PGM3 and GLO-PGM3, respectively, seems to be likely; close linkage can be excluded. From the relative map distances, but above all from the segregation of defined linkage phases in crossover families, we can hypothesize that the sequence order of the loci should be GLO-Bf-HLA-A-PGM3.
D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X; D003434:Crossing Over, Genetic; D008040:Genetic Linkage; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006801:Humans; D011995:Recombination, Genetic
D006680:HLA Antigens; D006649:Histocompatibility Antigens