title: Immunoglobulin changes in SLE.
abstract: In 39 patients serum total protein and albumin concentrations were stable throughout the course of systemic Lupus Erythematosus. While IgG concentrations were increased at diagnosis and returned to normal during follow-up, IgM concentrations followed the reverse pattern. IgA dynamics differed from IgG and IgM. IgA was normal at diagnosis and its concentrations rose throughout the disease.
mesh_terms: D000293:Adolescent; D000328:Adult; D001798:Blood Proteins / Q000032:analysis; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012709:Serum Albumin / Q000032:analysis; D013997:Time Factors
chemical_list: D001798:Blood Proteins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012709:Serum Albumin