Familial gingival fibromatosis associated with progressive deafness in five generations of a family.
Gingival hyperplasia may be inherited in a variety of ways, usually in an autosomal dominant or autosomal recessive manner. Additional phenotypic abnormalities are frequently associated with the gingival hyperplasia. To our knowledge, the family described here represents the first instance of autosomal dominantly inherited gingival hyperplasia associated with progressive neural hearing loss.
D000328:Adult; D002648:Child; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D003638:Deafness / Q000150:complications / Q000235:genetics*; D005260:Female; D005351:Fibromatosis, Gingival / Q000150:complications / Q000235:genetics*; D005881:Gingiva / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D013577:Syndrome