[Studies on the effect of thrombocytopenia on the rate of fibrin stabilization].
Severe thrombozytopenia, and therefore a lack of phospholipids, delays not only the thrombin formation rate but also, because of retarded factor XIII activation the fibrin stabilizing process. The other clotting factors, especially factor XIII, being within the normal range, this effect is only noted when the platelet count drops below 30 000/mm3.
D005169:Factor VIII / Q000494:pharmacology; D005176:Factor XIII / Q000494:pharmacology; D005260:Female; D005337:Fibrin / Q000096:biosynthesis*; D006801:Humans; D066298:In Vitro Techniques; D010743:Phospholipids; D013917:Thrombin / Q000502:physiology; D013921:Thrombocytopenia / Q000503:physiopathology*
D010743:Phospholipids; D005169:Factor VIII; D005337:Fibrin; D005176:Factor XIII; D013917:Thrombin
Untersuchungen über die Auswirkung von Thrombozytopenien auf die Fibrin-Stabilisierung