Leukocyte response to somatostatin in normals and patients with bacterial leukocytosis.
In normals and patients with acute bakterial leukocytosis synthetic somatostatin decreases cell count of stab neutrophils, neutrophils and eosinophils. After termination of somatostatin infusion a rebound phenomenon occurred. In healthy normals lymphocyte count increased during somatostatin infusion. This effect outlasts the end of infusion for more than 24 h. No significant effect could be demonstrated in patients with a bacterial leukocytosis.
D000328:Adult; D001424:Bacterial Infections / Q000097:blood; D004804:Eosinophils / Q000032:analysis; D005260:Female; D006410:Hematopoiesis / Q000187:drug effects*; D006801:Humans; D007958:Leukocyte Count; D007964:Leukocytosis / Q000382:microbiology*; D008297:Male; D009504:Neutrophils / Q000032:analysis; D010019:Osteomyelitis / Q000097:blood; D011702:Pyelitis / Q000097:blood; D013004:Somatostatin / Q000494:pharmacology*
D013004:Somatostatin