[Effect of synthetic poly-electrolytes of the cationic type on staphylococcal sensitivity to benzylpenicillin].
The study of the effect of synthetic polyelectrolites of the cationic type on benzylpenicillin resistant staphylococci showed that the cation polyelectrolites induced changes in the cell membrane permeability and increased penicillin absorption by the cells thus increasing sensitivity of the penicillin-resistant staphylococci to the antibiotic. Low inhibitory effect of the polyelectrolites with respect to penicillinase and hyaluronidase was shown. Changes in the membrane apparatus of staphylococcus cells due to the effect of polyelectrolites were found.
D001407:Bacillus / Q000201:enzymology; D002463:Cell Membrane Permeability / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D004357:Drug Synergism; D004573:Electrolytes / Q000494:pharmacology*; D010400:Penicillin G / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects*; D065093:beta-Lactamase Inhibitors
D004573:Electrolytes; D065093:beta-Lactamase Inhibitors; D010400:Penicillin G
Vliianie sinteticheskikh poliélektrolitov kationnogo tipa na ustoĭchivost' stafilokokkov k benzilpenitsillinu.