Modification of experimental UV erythema by external steroids--a reflex photometric study.
A method for reflex photometric detection of the modification of a model of inflammation (UV erythema) by external corticoids is presented. The steroids which most effectively suppress erythema formation are those which have the strongest vasoconstrictor potency also on unchanged skin. A tachyphylaxis phenomenon can also be demonstrated after several applications of a synthetic steroid to the inflammation model.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D004890:Erythema / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D010783:Photometry / Q000379:methods; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply; D014466:Ultraviolet Rays / Q000009:adverse effects; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D014662:Vasoconstrictor Agents