Urinary excretion of phenolic metabolites of N-(n-propyl)amphetamine in man.
In vivo metabolism of (+)-N-(n-propyl)amphetamine (NPA) in man (2 subjects) produced, among other products, two conjugated phenolic metabolites which are identified as 1-(4-hydroxyphenyl)-2-(n-propylamino)propane and 1-(4-hydroxy-3-methoxyphenyl)-2-n-propylamino)propane. In a 24 hr urine sample (pH uncontrolled), 13.4% of the NPA administered was excreted as the former, and 3.5% as the latter metabolite.
D000328:Adult; D000662:Amphetamines / Q000378:metabolism* / Q000652:urine; D006801:Humans; D008297:Male
D000662:Amphetamines