Stimulation of calcium accumulation in cardiac sarcolemma by phosphorylase kinase.
After incubation with phosphorylase kinase, calcium accumulation in cardiac sarcolemma was increased from 65+/-2 to 95+/-3nmol/10min per mg of protein. Under these conditions, phosphorylase kinase catalysed phosphorylation of membranes. This phosphorylation was hydroxylamine-insensitive, was stimulated by Ca2+ ions and was unaffected by 3':5'-cyclic AMP.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009206:Myocardium / Q000378:metabolism; D010764:Phosphorylase Kinase / Q000494:pharmacology*; D012508:Sarcolemma / Q000187:drug effects / Q000378:metabolism*
D010764:Phosphorylase Kinase; D002118:Calcium