Possible urate nephropathy of the newborn infant as a cause of transient renal insufficiency.
Oliguric renal failure, bilateral renal enlargement, and hyperuricemia were noted in three term infants. The findings on intravenous pyelography and radionuclide renography were consistent with intratubular obstruction to urinary outflow in two of the infants. The onset of diuresis appeared to follow intravenous pyelography in these infants. Urinary urate crystalluria was prominent in each infant in the first few days after the onset of diuresis, during which normal serum urate concentrations and normal renal function were established.
D004231:Diuresis; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000378:metabolism*; D007674:Kidney Diseases / Q000097:blood / Q000378:metabolism* / Q000652:urine; D011247:Pregnancy; D014527:Uric Acid / Q000097:blood / Q000378:metabolism* / Q000652:urine
D014527:Uric Acid