[State of neuromuscular transmission in rats with experimental hypoparathyroidism].
Experiments on albino rats with hypoparathyrosis demonstrated disturbances of the neuro-muscular transmission characterized by a decrease of the liminal strength of irritation in case of indirect stimulation, reduced amplitude of the muscle action potential, diminished latent period of response and absolute and relative refracterity phases and the character of muscular retention as well in indirect rhythmic stimulation. The investigated parameters displayed the same indices as in the control experiments following intravenous injection of proserine. Disturbances of the neuro-muscular transmission proved to be related to the presynaptic defect and could play a definite role in the development of the motor failure under conditions of hypoparathyrosis.
D000818:Animals; D004594:Electrophysiology; D007011:Hypoparathyroidism / Q000503:physiopathology*; D009469:Neuromuscular Junction; D051381:Rats; D011930:Reaction Time; D012032:Refractory Period, Electrophysiological
Sostoianie nervno-myshechnoĭ peredachi u krys s éksperimental'nym gipoparatireozom.