[HL-A B 27 a criterion for Reiter's syndrome].
The prevalence of 23 HLA antigens were examined in 21 patients with a typical Reiter's disease, 21 patients with incomplete Reiter's syndrome as well as 16 patients with non-gonococcal urethritis. HLA-B 27 antigen was found in 85,7% of patients with typical Reiter's disease as compared to 7,4% of 413 healthy controls. HLA-B 27 was also detectable in 57,1% of patients with clinical suspicion of Reiter's disease. No significant difference from the control frequencies of HLA specifities was found in patients with non-gonococcal urethritis. The association between HLA-B 27 and Reiter's syndrome is so marked that tissue typing is a valuable adjunct in the diagnosis of Reiter's syndrome.
D016918:Arthritis, Reactive / Q000276:immunology*; D001172:Arthritis, Rheumatoid / Q000276:immunology; D003937:Diagnosis, Differential; D006069:Gonorrhea / Q000276:immunology; D006680:HLA Antigens / Q000302:isolation & purification*; D006649:Histocompatibility Antigens / Q000302:isolation & purification*; D006801:Humans; D014526:Urethritis / Q000276:immunology
D006680:HLA Antigens; D006649:Histocompatibility Antigens
HLA-B 27 Ein Kriterium für das Reiter-Syndrom.