title: Oxygen breathing during exercise in patients with diffuse interstitial fibrosis.
abstract: 100% oxygen breathing during submaximal exercise in patients with diffuse interstitial lung disease diminishes cardiac output and pulmonary artery hypertension. The pressure drop in the pulmonary artery is most marked in patients with concomitant bronchial obstruction. At rest hyperoxia produced only minimal cardiopulmonary changes. The ventilatory and hemodynamic responses are discussed to find out if differences in these variables during oxygen breathing could be a reliable index for functional classification.
mesh_terms: D000328:Adult; D001784:Blood Gas Analysis; D006328:Cardiac Catheterization; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000503:physiopathology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000494:pharmacology*; D005082:Physical Exertion; D011658:Pulmonary Fibrosis / Q000503:physiopathology*; D012129:Respiratory Function Tests
chemical_list: D010100:Oxygen