[Pharmacokinetics of methylmethacrylate monomer of bone cements: method for qualitative and quantitative monomer determination in respiratory air].
The methylmethacrylate-monomer deported into circulation from bone cement implantation during endoprothetic operation is subject to unaltered exhalation. Qualitative evidence of monomer excretion in the exhaled air is established in animal experiment. The quantitative determination of monomer in the exhaled air in man undergoing hip-joint replacement are stated and the method is demonstrated. Pharmacocinetically exhalation has priority over metabolisation.
D000077:Acetabulum / Q000601:surgery; D000818:Animals; D002415:Cats; D004305:Dose-Response Relationship, Drug; D005269:Femur / Q000601:surgery; D006801:Humans; D008168:Lung / Q000378:metabolism; D008722:Methods; D008768:Methylmethacrylates / Q000032:analysis* / Q000097:blood; D012119:Respiration; D013147:Spirometry
D008768:Methylmethacrylates
Beitrag zur Pharmakokinetik von Methylmethacrylat-Monomer aus Knochenzementen: Methodik zur qualitativen und quantitativen Monomerbestimmung in der Atemluft