Experience with deep hypothermia and elective circulatory arrest for cardiac surgery in infants.
During hypothermic circulatory arrest (19 C nasal) averaging 55 minutes in 25 infants, the mean increase in base deficit was only --3.95 mEq/liter, when arterial gases before circulatory arrest were compared with samples ten minutes after perfusion had been resumed. Few significant arrhythmias occurred, and all survivors appeared neurologically normal at discharge.
D000136:Acid-Base Equilibrium / Q000187:drug effects; D000472:Alkalosis, Respiratory / Q000150:complications; D001145:Arrhythmias, Cardiac / Q000209:etiology; D001793:Blood Preservation; D002951:Citrates / Q000494:pharmacology; D005947:Glucose / Q000494:pharmacology; D006324:Heart Arrest, Induced; D006330:Heart Defects, Congenital / Q000601:surgery*; D006493:Heparin / Q000494:pharmacology; D006801:Humans; D007036:Hypothermia, Induced; D007223:Infant; D011183:Postoperative Complications; D011188:Potassium / Q000097:blood
D002951:Citrates; D006493:Heparin; D005947:Glucose; D011188:Potassium