title: Surgical treatment of hyperthyroidism in children.
abstract: During the past ten years, subtotal thyroidectomy for hyperthyroidism was performed upon 43 children at Childrens Hospital of Los Angeles. There were no deaths, no recurrent laryngeal nerve injuries and no permanent hypoparathyroidism. During the one to ten year follow-up period, one patient had recurrent hyperthyroidism develop and was treated with 131I. Twenty-five patients are hypothyroid and require thyroid supplement; 14 are euthyroid and receiv no medication. Postoperative thyroid function did not correlate well with gland remnant size, degree of fibrosis or the extent of lymphoid follicle formation. Lymphocytic infiltration was more severe in patients who had hypothyroidism develop postoperatively. Transient hypocalcemia developed in 22 patients. The effectiveness and safety of the surgical treatment for hyperthyroidism in children is reaffirmed, and it is advocated for consideration over 131I or prolonged medical therapy.
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000601:surgery*; D006996:Hypocalcemia / Q000209:etiology; D008297:Male; D011183:Postoperative Complications; D011300:Preoperative Care; D012008:Recurrence; D013965:Thyroidectomy