[Responses of different types of connective tissue to hormone administration].
The lysosomal glycosidase activity of the eye tissues (the sclera and cornea), the bone tissues and cartilage were studied. The intraperitoneal injection of tyrocalcitonine (TCT), deoxycorticosterone (DOCS), hydrocortisone (HC), and somatotropic hormone (STH) influenced both the activity of beta-galactosidase, beta-glucosidase, and hyaluronidase, the the functional state of thy lysosomal membranes of the connective tissues under investigation. GC and STH caused stabilization, whereas DOCS and large doses of TCT--a labilizing effect on the lysosomal membranes and tissues understudy. The absolute activity of the enzymes in the homogenates decreased after the HC and STH injection. DOCS produced an opposite effect.
D000818:Animals; D001842:Bone and Bones / Q000201:enzymology / Q000648:ultrastructure; D002116:Calcitonin / Q000494:pharmacology; D002356:Cartilage / Q000201:enzymology / Q000648:ultrastructure; D002682:Chinchilla; D003238:Connective Tissue / Q000201:enzymology / Q000648:ultrastructure*; D003315:Cornea / Q000201:enzymology / Q000648:ultrastructure; D003900:Desoxycorticosterone / Q000494:pharmacology; D005696:Galactosidases / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000378:metabolism; D013006:Growth Hormone / Q000494:pharmacology; D006728:Hormones / Q000494:pharmacology*; D006821:Hyaluronoglucosaminidase / Q000378:metabolism; D006854:Hydrocortisone / Q000494:pharmacology; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D011817:Rabbits; D012590:Sclera / Q000201:enzymology / Q000648:ultrastructure
D006728:Hormones; D003900:Desoxycorticosterone; D013006:Growth Hormone; D002116:Calcitonin; D005696:Galactosidases; D006026:Glycoside Hydrolases; D006821:Hyaluronoglucosaminidase; D006854:Hydrocortisone
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