Autoantibodies to Tamm-Horsfall protein in detection of vesicoureteric reflux and kidney scarring.
Measurement of IgG antibodies to Tamm-Horsfall protein (ATHA) in 92 bacteriuric schoolgirls aged 5-12 did not show a significant rise compared with the titres found in the sera of 24 healthy controls. ATHA titres showed no correlation with the presence of vesicoureteric reflux or kidney scarring and it is concluded that measurement of serum ATHA is of no value as a screening procedure for the detection of vesicoureteric reflux.
D001323:Autoantibodies / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007674:Kidney Diseases / Q000276:immunology* / Q000517:prevention & control; D009088:Mucoproteins / Q000276:immunology*; D014718:Vesico-Ureteral Reflux / Q000175:diagnosis* / Q000276:immunology
D001323:Autoantibodies; D007074:Immunoglobulin G; D009088:Mucoproteins