Discrepancies in nude mice.
With the increasing number of publications in which nude mice are used, there is a growing list of apparent discrepencies. To avoid such problems, we propose the use of nude mouse populations with a large gene pool which will leave, if possible, the nude allele as the only homozygote. All phenotypic characters consistently different between nu/nu, nu/+ and +/+ mice could then, with more certainty, be linked with the nude mutation.
D000818:Animals; D001947:Breeding; D003433:Crosses, Genetic; D005838:Genotype; D051379:Mice; D008819:Mice, Nude / Q000276:immunology*; D010641:Phenotype