[Protein synthesis during the period of mitotic recovery following exposure to colchicine and colcemide].
Autoradiographic study with leucine-3H showed the restoration of normal mitosis course after the action of colchicine on the culture of Chinese hamster cells to be accompanied by a marked activation of the protein synthesis exceeding the initial level. This intensification of protein synthesis precedes complete normalization of the mitotic activity in the cell culture. The course of normalization under the influence of colcemide is characterized only by the stabilization of the protein synthesis at the initial control level.
D000818:Animals; D001345:Autoradiography; D002999:Clone Cells; D003078:Colchicine / Q000031:analogs & derivatives* / Q000494:pharmacology*; D006224:Cricetinae; D008938:Mitosis / Q000187:drug effects*; D014176:Protein Biosynthesis
D003078:Colchicine
Sintez belkov v periode vosstanovleniia mitoza posle deĭstviia kolkhitsina i koltsemida.