[Growth hormone, LH and FSH under function dynamical conditions in serum and basic corticol and testosterone serum levels in brain-injured patients during dexamethasone treatment].
In 14 male patients with severe head injury the following hormones were measured by radioimmunological methods in plasma: Basal levels of LH, FSH, GH, testosterone and total corticoids; furthermore LH-releasing-hormone- and insulin-hypoglycaemia-tests were done. The investigations have shown, that in patients with severe head injury no essential impairment of the hypothalamus-hypophyseal-system controlled by LH-, FSH- and GH-secretion could be detected. Diminished testosterone and accelerated LH-levels are measurable, whereas total corticoids were not significantly accelerated. Because of treatment with dexamethasone the effect of this substance has to be discussed.
D000293:Adolescent; D000328:Adult; D001930:Brain Injuries / Q000097:blood* / Q000188:drug therapy; D003907:Dexamethasone / Q000494:pharmacology* / Q000627:therapeutic use; D005640:Follicle Stimulating Hormone / Q000097:blood*; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D007030:Hypothalamo-Hypophyseal System; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D013739:Testosterone / Q000097:blood*
D013739:Testosterone; D003907:Dexamethasone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013006:Growth Hormone; D006854:Hydrocortisone
Wachstumshormon, LH und FSH unter funktions-dynamischen Bedingungen im Serum sowie basale Kortisol- und Testosteron-Serumspiegel bei Schädel-hirnverletzten unter Dexamethasonbehandlung.