[Elevated serum-sialyltransferase activity in human malignant diseases: a new diagnostic tool? (author's transl)].
Sialyltransferase activity was estimated in serum samples of patients with cancer and controls using immobilized asialo-fetuin as the acceptor and cytidine-5'-monophospho [14C] sialic acid as the donor. The data suggest that increased enzyme activity can be found in more than 80% of the samples from patients with malignant diseases.
D001943:Breast Neoplasms / Q000201:enzymology; D001984:Bronchial Neoplasms / Q000201:enzymology; D002277:Carcinoma / Q000201:enzymology; D003110:Colonic Neoplasms / Q000201:enzymology; D005260:Female; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis / Q000201:enzymology*; D010051:Ovarian Neoplasms / Q000201:enzymology; D012509:Sarcoma / Q000201:enzymology; D012799:Sialyltransferases / Q000097:blood*; D013964:Thyroid Neoplasms / Q000201:enzymology; D014166:Transferases / Q000097:blood*
D014166:Transferases; D012799:Sialyltransferases
Erhöhung der Serum-Sialyltransferase bei menschlichen Malignomen: Grundlage für ein neues Diagnosticum?.