Anti-fab' antibodies in human sera. I. A study of their distribution in health and disease.
Antibodies to the Fab' fragments of human IgG are commonly found in human sera. This study shows that the incidence of such antibodies is higher in women, both blood donors and hospital patients, than in men: it is no higher in patients with malignant disease than in hospital patients of the same sex without malignancies. The incidence in hospital patients is always greater than in healthy blood donors. The presence of Fab' antibodies is not related to pregnancy. The greatest difference in the frequency of such antibodies occurs between males and females under the age of 50.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000906:Antibodies / Q000032:analysis*; D044383:Black People; D001782:Blood Donors; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000276:immunology; D010361:Patients; D012737:Sex Factors; D044465:White People
D000906:Antibodies; D007140:Immunoglobulin Fab Fragments