(2-Ethoxyethoxy)acetic acid: an unusual compound found in the gas chromatographic analysis of urinary organic acids.
An unknown acidic compound was detected in a number of urine samples from patients with a suspected metabolic disorder and some patients treated with chemotherapy. The structure of this compound has been characterized as (2-ethoxyethoxy)acetic acid, using a gas chromatography/mass spectrometry/computer system. The authentic compound was synthesized and compared with the unknown. Urinary (2-ethoxyethoxy)acetic acid is assumed to be formed endogenously from an exogenous precursor, probably 2-(2-ethoxyethoxy)ethanol.
D000085:Acetates / Q000138:chemical synthesis / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D002849:Chromatography, Gas; D005019:Ethyl Ethers / Q000652:urine*; D005026:Ethylene Glycols; D005260:Female; D006801:Humans; D007223:Infant; D013058:Mass Spectrometry; D014835:Volatilization
D000085:Acetates; D005019:Ethyl Ethers; D005026:Ethylene Glycols; C014537:(2-ethoxyethoxy)acetic acid