title: The effect of alcohol and smoking on testosterone function and aggression in chronic alcoholics.
abstract: Forty alcoholics without other significant medical or psychiatric problems were studied on a research ward for two weeks. All subjects abstained from alcohol and cigarettes during the first week; 30 randomly selected subjects were permitted unlimited alcohol and/or cigarettes during the second week. Plasma testosterone levels were normal during the first week but decreased rapidly and significantly in those subjects allowed alcohol. A variety of measures of affect failed to show a significant correlation between hostility/aggression and plasma testosterone levels or alcohol ingestion.
mesh_terms: D000328:Adult; D000339:Affect / Q000187:drug effects; D000374:Aggression / Q000187:drug effects*; D000437:Alcoholism / Q000150:complications*; D001007:Anxiety / Q000209:etiology; D003863:Depression / Q000209:etiology; D000431:Ethanol / Q000494:pharmacology*; D006791:Hostility / Q000187:drug effects; D006801:Humans; D008297:Male; D009538:Nicotine / Q000494:pharmacology; D012907:Smoking / Q000150:complications*; D013739:Testosterone / Q000097:blood*
chemical_list: D000431:Ethanol; D013739:Testosterone; D009538:Nicotine