Nuclease for DNA apurinic sites in chicken liver.
Chicken liver crude extract produced acid-soluble diphenylamine-positive material in the presence of depurinated and alkylated DNA, while the formation of such material from normal and single stranded DNA was comparatively low. The maximum acid-soluble material produced was not increased further by alkali, indicating that the enzymatic action is mostly directed towards apurinic sites.
D000818:Animals; D001080:Apurinic Acid; D002645:Chickens; D003851:Deoxyribonucleases / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D011119:Polynucleotides
D011119:Polynucleotides; D001080:Apurinic Acid; D003851:Deoxyribonucleases