Efficacy of various drugs for treatment of giardiasis. A comparative study.
A total of 172 patients with giardiasis were treated with four of the drugs most commonly used for this infection. All drugs were used in their usual posologic schedules. The cure rates achieved with furazolidone, nimorazole, metronidazole, and tinidazole were; respectively, 72%, 94%, 87%, and 97%, while in a control group given no medication stools of only 35% of the patients became negative. Side effects were of minor importance in patients treated with nimorazole and metronidazole, and were somewhat more frequent and severe in those treated with furazolidone. Tinidazole produced no side effects.
D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D002648:Child; D004341:Drug Evaluation; D005664:Furazolidone / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D005873:Giardiasis / Q000188:drug therapy*; D006801:Humans; D008795:Metronidazole / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D009554:Nimorazole / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D009593:Nitroimidazoles / Q000627:therapeutic use*; D014011:Tinidazole / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use
D000981:Antiprotozoal Agents; D009593:Nitroimidazoles; D014011:Tinidazole; D008795:Metronidazole; D009554:Nimorazole; D005664:Furazolidone