title: Luxation of the globe in Engelmann's disease.
abstract: A 35-year-old woman with Engelmann's disease and systemic lupus erythematosus developed spontaneous luxation of the globe and glaucoma. Radiological studies demonstrated increased sclerosis of the orbital bones and decreased orbital volumes, the probable cause of the luxation and the glaucoma. The glaucoma was controlled with pilocarpine eyedrops and the luxation spontaneously reduced. The systemic administration of corticosteroids for the control of Engelmann's disease and systemic lupus erythematosus may have been a contributory factor in the etiology and management of glaucoma.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use; D000328:Adult; D001847:Bone Diseases / Q000150:complications; D001848:Bone Diseases, Developmental / Q000150:complications*; D003966:Camurati-Engelmann Syndrome / Q000150:complications* / Q000188:drug therapy; D005128:Eye Diseases / Q000209:etiology*; D005260:Female; D005901:Glaucoma / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy; D009915:Orbit / Q000000981:diagnostic imaging; D010375:Pedigree; D010862:Pilocarpine / Q000627:therapeutic use; D011859:Radiography
chemical_list: D000305:Adrenal Cortex Hormones; D010862:Pilocarpine