Comparative effect of anaerobic coryneforms on a murine melanoma.
Ten strains of anaerobic Corynebacteria were compared in their effect on survival of C57BL/6 mice, bearing subcutaneously inoculated B16 melanomas. The corynebacterial suspensions were injected intralesionally twice weekly for five injections. Significant permanent tumor regression was not obtained. Significant prolongation of survival was observed in mice treated with seven of the corynebacterial strains.
D000818:Animals; D003352:Corynebacterium / Q000276:immunology*; D005260:Female; D007167:Immunotherapy; D008545:Melanoma / Q000628:therapy*; D051379:Mice; D008810:Mice, Inbred C57BL; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000628:therapy; D011425:Propionibacterium acnes / Q000276:immunology*