Aspirin therapy in microangiopathic hemolytic anemia and renal failure.
An 18-year-old man presented initially with findings compatible with disseminated intravascular coagulation. Following a brief partial response to intravenous heparin therapy rapid deterioration of renal function was associated with evidence of a hypercoagulable state characterized primarily by excessive platelet aggregation and sequestration. Initiation of aspirin therapy led to a prompt rise in the platelet count and permanent improvement in renal function.
D058186:Acute Kidney Injury / Q000150:complications / Q000188:drug therapy*; D000293:Adolescent; D000743:Anemia, Hemolytic / Q000150:complications / Q000188:drug therapy*; D001241:Aspirin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008833:Microcirculation; D013921:Thrombocytopenia / Q000150:complications / Q000188:drug therapy
D001241:Aspirin