[Effect of increased calcium ion concentration on the electrical and contractile activity of guinea pig ureter smooth muscle].
Experiments were performed on the smooth muscle cells of the guinea pig ureter by means of the double sucrose-gap method. An increase of Ca2+ concentration (22 mM/1) in Ringer-Locke solution causes hyperpolarization and a slight increase of the membrane resistance. The amplitude of the first spike potential and the plateau decreases, the amplitude of oscillations increases. In sodium-free Ringer-Locke solution when the action potential in the smooth muscle cells of the ureter turns into a simple spike potential, an increase of Ca2+ concentration causes a marked increase of the action potential amplitude.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D003106:Colon; D006168:Guinea Pigs; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects*; D014513:Ureter
D002118:Calcium
Vliianie povyshennoĭ kontsentratsii ionov kal'tsiia na élektricheskuiu i sokratitel'nuiu aktivnost' gladkikh myshts mochetochnika morskoĭ svinki.