title: [Rhodosporidium Banno: yeast phase inactivation by ultraviolet light and N-methyl-N'-nitro-N-nitrosoguanidine].
abstract: The inactivation of stationary phase cells by ultraviolet light (UV) and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) was examined in eight wild strains of Rhodotorula, six of which are the sporidial yeast phase of Rhodosporidium, a basidiomycetous fungus. It has been found that (1) the UV-resistance of Rhodosporidium and Rhodotorula yeasts is higher and the MNNG-resistance lower than the resistance of Candida and Hansenula yeasts, (2) the shape of the survival curves is sigmoid in the case of UV and two-phase exponential in the case of MNNG, (3) the mutagen sensitivities but not the inactivation kinetics of the strains are different, (4) the UV- and MNNG-sensitivities for each of the strains are correlated, (5) the relatively high resistance to UV cannot be due to the carotenoid pigments of the cells, (6) mutations to UV-sensitivity can be induced with a high rate, (7) the sigmoidal character of the UV survival curves were reduced or transformed to an exponential shape by the UVS-mutations.
mesh_terms: D001487:Basidiomycota / Q000254:growth & development*; D002338:Carotenoids; D004305:Dose-Response Relationship, Drug; D004307:Dose-Response Relationship, Radiation; D008769:Methylnitronitrosoguanidine / Q000494:pharmacology*; D009154:Mutation; D014466:Ultraviolet Rays; D014587:Ustilaginales / Q000187:drug effects / Q000254:growth & development* / Q000528:radiation effects
chemical_list: D008769:Methylnitronitrosoguanidine; D002338:Carotenoids
vernacular_title: Rhodosporidium Banno: Inaktivierende Wirksamkeit von ultraviolettem Licht und N-Methyl-N'-nitro-N-nitrosoguanidin in der Hefephase.