Regeneration of the retina in the adult newt, Triturus cristatus, following surgical division of the eye by a post-limbal incision.
An autoradiographic and histological study of retinal regeneration following a post-limbal ocular incision, in Triturus cristatus, is described. In these cases there is a major contribution to the regenerating retina from both the anterior complex (pars ciliaris retinae: ora serrata) and the retinal pigment epithelium. The tissue derived from the anterior complex can independently differentiate into retinal tissue if the anterior and posterior parts of the regenerate do not join. This contrasts with the situation following a limbal incision to the eye where the regenerative response of the anterior complex is inhibited. The significance of labelling patterns in the regenerating retina, following administration of 3H-thymidine, is discussed.
D000818:Animals; D001345:Autoradiography; D008032:Limbic System / Q000502:physiology*; D012038:Regeneration; D012160:Retina / Q000033:anatomy & histology / Q000378:metabolism / Q000502:physiology*; D012455:Salamandridae / Q000502:physiology*; D013936:Thymidine / Q000378:metabolism; D014562:Caudata / Q000502:physiology*
D013936:Thymidine