title: A short parameter-fitting routine for compartmental models.
abstract: We have developed a program of 298 FORTRAN statements which obtains the inter-pool exchange rates and other parameters of a compartmental system, working directly from the time course of tracer activity after a bolus injection. The fitting problem - data and model - is specified by the user in a natural syntactic style. The program calculates least-squares estimates, confidence limits and intercorrelation estimates for the fitted parameters. Its small size and conceptual simplicity make the program a powerful practical tool for analyzing tracer studies.
mesh_terms: D003201:Computers; D008433:Mathematics; D008954:Models, Biological; D011849:Radioactive Tracers; D011868:Radioisotopes
chemical_list: D011849:Radioactive Tracers; D011868:Radioisotopes