Kinetic behaviour of microsomal styrene monooxygenase and styrene epoxide hydratase in different animal species.
The apparent Km and Vmax values of styrene epoxide forming monooxygenase and styrene epoxide hydratase have been evaluated in the liver microsomes of male rats, mice, guinea-pigs and rabbits. Epoxide hydratase gave much higher and more uniform Km values than the monooxygenase in the species considered.
D000818:Animals; D002273:Carcinogens / Q000378:metabolism; D004851:Epoxide Hydrolases / Q000378:metabolism*; D006168:Guinea Pigs; D006836:Hydro-Lyases / Q000378:metabolism*; D007700:Kinetics; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D010088:Oxidoreductases / Q000378:metabolism*; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013343:Styrenes / Q000378:metabolism*
D002273:Carcinogens; D013343:Styrenes; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D004851:Epoxide Hydrolases; D006836:Hydro-Lyases