Male pseudohermaphroditism due to partial end-organ insensitivity to androgens.
A 46XY individual with incomplete male pseudohermaphroditism was studied. The phenotype was distinctive, with a masculine habitus despite a small phallus, gynaecomastia and diminished virilization. Plasma levels of testosterone, oestrogens, gonadotrophins and sex-hormone binding globulin were elevated. It is proposed that this syndrome is a variant of Type I incomplete male pseudohermaphroditism.
D000328:Adult; D012734:Disorders of Sex Development / Q000097:blood / Q000209:etiology*; D012739:Gonadal Steroid Hormones / Q000097:blood; D006065:Gonadotropins, Pituitary / Q000097:blood; D006801:Humans; D008297:Male; D010641:Phenotype; D011944:Receptors, Androgen; D011987:Receptors, Steroid
D012739:Gonadal Steroid Hormones; D006065:Gonadotropins, Pituitary; D011944:Receptors, Androgen; D011987:Receptors, Steroid