Electrically-induced mechanical activity of the isolated guinea-pig sciatic nerve. Influences of calcium and anoxia.
The electrically-induced motility of isolated segments of guinea-pig sciatic nerves is reported. This motility was characterized by waves of tensional variations. The removal of Ca2+ from the suspending solution, the addition of EDTA as well as anoxia, resulted in a decrement of tension accompanied by a prolonged duration of the cycles of mechanical activity.
D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D004553:Electric Conductivity; D004558:Electric Stimulation; D006168:Guinea Pigs; D000860:Hypoxia / Q000503:physiopathology*; D012584:Sciatic Nerve / Q000187:drug effects / Q000502:physiology* / Q000503:physiopathology
D002118:Calcium