Radiochemical GLC assay for nortriptyline in human plasma.
A novel method was developed for the assay of nortriptyline in plasma. After nortriptyline was extracted, it was acetylated with 3H-acetic anhydride; the quantity of 3H-acetylnortriptyline in the extract was determined by radiochemical GLC. The method is capable of assaying 5 ng of nortriptyline/ml of plasma. The instrumentation was assembled from commercially available components.
D000107:Acetylation; D002849:Chromatography, Gas; D006801:Humans; D008722:Methods; D009661:Nortriptyline / Q000031:analogs & derivatives / Q000097:blood*; D014316:Tritium
D014316:Tritium; D009661:Nortriptyline