Antibody-mediated cytotoxicity in rheumatoid arthritis.
Patients with active seropositive rheumatoid arthritis have reduced antibody-mediated cytotoxicity. Synovial fluid lymphocytes have very low cytotoxicity. A relationship appears to exist between disease activity and cytotoxic activity.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000906:Antibodies; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012217:Rheumatoid Factor / Q000032:analysis; D013582:Synovial Fluid / Q000166:cytology
D000906:Antibodies; D012217:Rheumatoid Factor