[Brothers affected by the Charcot-Marie-Tooth peroneal muscular atrophy with a positive variant of the anticipation phenomenon].
Considering the genetical peculiarity of Charcot-Marie-Tooth's muscular atrophy, a family with three affected brothers was investigated, in which beginning date was discovered to be progressively antedated. Afterwards, this possible variant of anticipation is discussed, because such condition is quite ununsual, not only in this disease, but in Human Genetics, in a general sense.
D000328:Adult; D002607:Charcot-Marie-Tooth Disease / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D005360:Fibula; D006801:Humans; D008297:Male; D008875:Middle Aged; D009133:Muscular Atrophy / Q000235:genetics*
Irmandade afetada pela atrofia muscular peroneal de Charcot-Marie-Tooth com possivel variante do fenomeno da antecipação