title: [Heterochronous maturation of pathways from muscle and skin receptors to the sensomotor cortex in rabbits].
abstract: Analysis of structural and functional maturation of peripheral afferent projections from the skin and muscle receptors of the n. ischiadicus to sensorimotor cortex during postnatal ontogeny in rabbits, as the criterion of functional maturity of the peripheral nervous fibers, had their sensitivity to blocking effect of novocain during its application to the muscle and skin branches of the n. ischiadicus. During the ontogeny, the sensitivity was changing wcich was followed by changes in the shape of the cortical evoked response. The morphological maturity of the peripheral fibers was estimated by the degree of their myelinization. The afferent impulses were found to have different channels of conduction yet at the level of peripheral nervous fibers. This implies participation of different peripheral fibers in organization of EP components in the cortex. The fibers mature heterochronously during the ontogeny, the same is true for maturation of afferent projections from the muscle and skin receptors.
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D005071:Evoked Potentials; D009044:Motor Cortex / Q000502:physiology*; D009132:Muscles / Q000294:innervation*; D010525:Peripheral Nerves / Q000187:drug effects / Q000254:growth & development / Q000502:physiology*; D011343:Procaine / Q000494:pharmacology; D011817:Rabbits; D011984:Sensory Receptor Cells / Q000502:physiology; D012867:Skin / Q000294:innervation*; D013003:Somatosensory Cortex / Q000502:physiology*
chemical_list: D011343:Procaine
vernacular_title: Geterokhronnoe sozrevanie puteĭ impul'satsii ot myshechnykh i kozhnykh retseptorov k sensomotornoĭ kore u krolikov.