title: Some observations on the choice of detergent for solubilization of the human erythrocyte membrane.
abstract: Solubilization of the human erythrocyte membrane by seven detergents is described. Components released into the supernatant or retained in the residue were identified by sodium dodecyl sulphate/polyacrylamide-gel electrophoresis. Two non-ionic detergents exhibiting little u.v. absorption were more efficient than u.v.-absorbing Triton X-100. Evidence is presented of an interchange between protein PAS 1 and protein PAS 2.
mesh_terms: D003902:Detergents / Q000494:pharmacology*; D004910:Erythrocyte Membrane / Q000187:drug effects*; D004912:Erythrocytes / Q000187:drug effects*; D006801:Humans; D008565:Membrane Proteins / Q000302:isolation & purification; D011092:Polyethylene Glycols / Q000494:pharmacology; D011136:Polysorbates / Q000494:pharmacology; D012995:Solubility
chemical_list: D003902:Detergents; D008565:Membrane Proteins; D011136:Polysorbates; D011092:Polyethylene Glycols