Amino acid composition and sequence of kassinin, a tachykinin dodecapeptide from the skin of the African frog Kassina senegalensis.
Methanol extracts of the skin of the African amphibian Kassina senegalensis contain a dodecapeptide, kassinin, belonging to the family of tachykinins or physalaemin-like peptides. Kassinin, like all other natural tachykinins, possesses the characteristic C-terminal tripeptide Gly-Leu-Met-NH2 and a phenylalanine residue in position 5 from the C-terminus. However, the amino acid sequence in the N-moiety of the molecule differs sharply from that of the other tachykinins.
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001001:Anura; D001681:Biological Assay; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects; D009842:Oligopeptides / Q000302:isolation & purification / Q000494:pharmacology; D010446:Peptide Fragments / Q000032:analysis; D012867:Skin / Q000032:analysis
D000596:Amino Acids; D009842:Oligopeptides; D010446:Peptide Fragments