[Correlation of parathormone determination and bone biopsy in primary hyperparathyroidism].
Eleven patients with primary hyperparathyroidism confirmed by histologic examination were subjected to a comparative study of the results of quantitative determination of parathormone and of quantitative bone biopsy. Quantitative radioimmunologic determination of parathormone was carried out with the aid of an N-terminal specific anti serum, while the histologic features studied were the periosteocytic and osteoclastic absorption surfaces. On the basis of a combination of the results of these two techniques, the diagnosis could be made in all the cases studied. A statistically significant correlation was observed between the results of quantitative determination of parathormone and those of histologic examination of the surfaces of periosteocytic lacunae (r = 0.63; p = 0.05).
D001842:Bone and Bones / Q000473:pathology*; D005069:Evaluation Studies as Topic; D006801:Humans; D006961:Hyperparathyroidism / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D010281:Parathyroid Hormone / Q000097:blood*; D010521:Periosteum / Q000473:pathology
D010281:Parathyroid Hormone
Etude corrélative du dosage de parathormone et de la biopsie osseuse dans l'hyperparathyroïdisme primitif.