[Selectivity of beta-adrenergic compounds. IV. Studies on 1-(4'-methylphenyl)-2-isopropylaminopropanol].
The beta-adrenergic activity of 1-(4'-methylphenyl)-2-isopropylaminopropanol (H 35/25) was studied on isolated preparations (guinea pig atria, guinea pig and calf tracheal muscle, mouse cecum). H 35/25 shows variations in both affinity and intrinsic activity at the various levels tested. The discussion shows that this cannot be used as a means of characterizing beta-adrenergic receptors.
D000818:Animals; D002417:Cattle; D002432:Cecum / Q000187:drug effects; D006168:Guinea Pigs; D006325:Heart Atria / Q000187:drug effects; D051379:Mice; D009130:Muscle, Smooth / Q000187:drug effects; D011412:Propanolamines / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology; D014132:Trachea / Q000187:drug effects
D011412:Propanolamines; D011433:Propranolol
Selettività dei composti beta-adrenergici. IV. Osservazioni sull'1-(4'-metilfenil)-2-isopropilaminopropanolo.