[Peripheral regulation of the cholinergic mediator process in the smooth muscles of the rat small intestine].
A physiologically active substance (X-factor) is released from smooth muscle fibers of rat's small intestine-donor under the effect of acetylcholine. This substance which seems to be a macroergic nature strengthens the spontaneous activity of isolated piece of rat's small intestine-recipient and increases its sensitivity to acetylcholine almost twofold. Participation of the X-factor in the control of cholinoreceptor activity of smooth muscle fibers of rat's small intestine following the pattern of positive feedback, is discussed.
D000109:Acetylcholine / Q000494:pharmacology*; D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D004140:Dinitrophenols / Q000494:pharmacology; D005769:Gastrointestinal Motility; D007421:Intestine, Small / Q000378:metabolism; D008297:Male; D009130:Muscle, Smooth / Q000378:metabolism*; D051381:Rats; D011950:Receptors, Cholinergic; D013268:Stimulation, Chemical; D014020:Tissue Extracts / Q000494:pharmacology*; D014500:Uracil Nucleotides / Q000494:pharmacology
D004140:Dinitrophenols; D011950:Receptors, Cholinergic; D014020:Tissue Extracts; D014500:Uracil Nucleotides; D000255:Adenosine Triphosphate; D000109:Acetylcholine
Perifericheskaia reguliatsiia kholinergicheskogo mediatornogo protsessa v gladkikh myshtsakh tonkoĭ kishki krysy.