Synthesis of dolichol derivatives in human erythrocyte membranes.
Human erythrocyte membranes contain the enzymes responsible for the synthesis of dolichol-P-glucose, dolichol-P-mannose, dolichol-PP-N-acetylglucosamine, dolichol-PP-NN' diacetylchitobiose and of dolichol-PP-oligosaccharides containing NN' diacetylchitobiose and mannose or the same sugar residues plus glucose. The transfer of the oligosaccharide moieties from the dolichol-PP-oligosaccharides to endogenous proteins could not be detected. These enzymes appeared to be integral membrane proteins.
D004224:Diterpenes / Q000097:blood*; D004286:Dolichols / Q000097:blood*; D004910:Erythrocyte Membrane / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D009994:Osmolar Concentration; D010743:Phospholipids / Q000096:biosynthesis / Q000097:blood*
D004224:Diterpenes; D004286:Dolichols; D010743:Phospholipids