Antibody-induced antigen redistribution and shedding from human breast cancer cells.
Cell surface antigens of human breast cancer cells undergo a rapid redistribution when bound by antibodies from cancer patients. The subsequent shedding of these antigen-antibody complexes and free antigen may be instrumental in tumor survival.
D000912:Antibodies, Neoplasm; D000936:Antigen-Antibody Complex; D000937:Antigen-Antibody Reactions; D000951:Antigens, Neoplasm; D001943:Breast Neoplasms / Q000276:immunology*; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G; D013696:Temperature; D013997:Time Factors
D000912:Antibodies, Neoplasm; D000936:Antigen-Antibody Complex; D000951:Antigens, Neoplasm; D007074:Immunoglobulin G