Effect of intraluminal oxygen on endotoxin absorption in experimental occlusion of the superior mesenteric artery.
Absorption of bacterial endotoxin has been shown to occur after release of the occluded superior mesenteric artery in the rat. A significant reduction in endotoxin absorption was observed as a result of the infusion of gaseous oxygen into the bowel lumen during the period of ischaemia (P less than 0-001). The methods of endotoxin identification and assay are described, and the possible reasons for this effect of intraluminal oxygen are discussed.
D000818:Animals; D004731:Endotoxins / Q000378:metabolism* / Q000633:toxicity; D005260:Female; D007408:Intestinal Absorption; D008297:Male; D008638:Mesenteric Arteries / Q000503:physiopathology; D008641:Mesenteric Vascular Occlusion / Q000378:metabolism*; D051379:Mice; D010100:Oxygen / Q000008:administration & dosage; D051381:Rats
D004731:Endotoxins; D010100:Oxygen