title: A modern approach to management of pregnant diabetics: a two-year analysis of perinatal outcomes.
abstract: Increased understanding of maternal-fetal carbohydrate homeostasis together with modern perinatal technology now provides a more rational basis for obstetric management of the pregnant diabetic patient. These concepts were applied at MacDonald House in the care of 96 diabetic pregnant women over a two-year period. Pregnancy outcomes were compared with prior experiences with the same group of women. The perinatal mortality rate was reduced from 13.5 to 4.2%, and the rate of macrosomia (infants large for gestational age) was reduced from 30.9 to 17.7%. Patients with gestational diabetes, with a prior loss rate of 8.3%, suffered no losses in the current series. Maternal age was not found to correlate with an untoward outcome in this subgroup.
mesh_terms: D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D036861:Delivery, Obstetric / Q000379:methods; D005260:Female; D005313:Fetal Death; D005865:Gestational Age; D006130:Growth Disorders / Q000209:etiology; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007328:Insulin / Q000627:therapeutic use; D008423:Maternal Age; D009820:Ohio; D010298:Parity; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000145:classification / Q000453:epidemiology / Q000628:therapy*
chemical_list: D001786:Blood Glucose; D007328:Insulin