Reduction in inspiratory activity in response to sternal vibration.
It has been shown previously that there is a reduction in tidal volume in response to longitudinal sternal vibration at 100 Hz. In the present study it was shown that the effect of such vibration is to reduce tidal volume (VT) and prolong inspiratory time (ti) in such a way that points from vibrated and non-vibrated breaths fall on the same VT:ti curve. This indicates that the normal mechanisms which terminate inspiration are unaffected by vibration. The effect of vibration is simply to reduce the rate at which inspiration proceeds. This was illustrated here when vibration reduced the rate of fall of intrapleural pressure during inspiration, and also reduced the instantaneous ventilation at any level of chemical drive. Electrophysiological recordings made here from phrenic motoneurones support these findings. It is concluded that sensory nerves in the chest wall, which can be excited by vibration, can inhibit inspiration.
D000818:Animals; D002415:Cats; D005260:Female; D008297:Male; D010994:Pleura / Q000502:physiology; D011312:Pressure; D012119:Respiration; D013249:Sternum / Q000294:innervation*; D013990:Tidal Volume; D014630:Vagus Nerve / Q000502:physiology; D014732:Vibration