[Effect of x-irradiation on DNA-synthesis in uterine gland epithelium and the relationship of that effect to the phase of the mitotic cycle].
The autoradiographic method with the use of thymidone-3H was applied to the study of X-irradiation influence on the DNA synthesis in the epithelium of the endometrial glands of ovariectomized mice stimulated with synestrol, and of the dependence of this action on the mitotic cycle phase. It appeared that in local irradiation of the uterus with a dose of 400 r reduction of the labeled nuclei index (LNI) in the cells of the endometrial glands differed and depended on the mitotic cycle phase of the majority of the cells.
D000818:Animals; D002369:Castration; D004247:DNA / Q000096:biosynthesis / Q000528:radiation effects*; D004717:Endometrium / Q000378:metabolism / Q000528:radiation effects*; D004848:Epithelium; D005260:Female; D006589:Hexestrol / Q000494:pharmacology; D051379:Mice; D008938:Mitosis; D014965:X-Rays
D006589:Hexestrol; D004247:DNA
Deĭstvie rentgenooblucheniia na sintez DNK v épitelii matochnykh zhelez i zavisimost' étogo deĭstviia ot fazy mitoticheskogo tsikla.