The effect of hydroxyethylrutosides on capillary filtration rate in the lower limb of man.
The rate of capillary filtration in the lower limbs after hydroxyethylrutosides administered in various doses and by different routes was studied in patients with chronic venous insufficiency. Capillary filtration rate decreased immediately after intravenous and from 55 to 85 minutes after oral administration, depending on the dose. The slow-release tablets produced a definite falt in capillary filtration 240 minutes after administration.
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D002199:Capillary Permeability / Q000187:drug effects*; D003692:Delayed-Action Preparations; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006896:Hydroxyethylrutoside / Q000008:administration & dosage / Q000494:pharmacology*; D007275:Injections, Intravenous; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D010919:Placebos; D012431:Rutin / Q000031:analogs & derivatives*; D013997:Time Factors
D003692:Delayed-Action Preparations; D006896:Hydroxyethylrutoside; D010919:Placebos; D012431:Rutin