[Cytomorphological study of lincomycin toxicity].
It was concluded on the basis of the analysis pf the experimental data that lincomycin had a low cytotoxic effect in cell culture and exerted no embryotoxic effect on chick embryoes. Histological examinations showed that on intravenous administration lincomycin had a low irritating effect on the vessel walls and on intramuscular administration it had an insignificant irritating effect without any signs of total toxic effect.
D000818:Animals; D002478:Cells, Cultured / Q000187:drug effects*; D002642:Chick Embryo; D004305:Dose-Response Relationship, Drug; D005347:Fibroblasts / Q000187:drug effects; D008034:Lincomycin / Q000633:toxicity*; D008099:Liver / Q000166:cytology; D008938:Mitosis / Q000187:drug effects; D011817:Rabbits; D051381:Rats; D013997:Time Factors
D008034:Lincomycin
Tsitomorfologicheskoe izuchenie toksichnosti linkomitsina.