[Comparison of the efficacy of parenteral and enteral pertussis immunization in the rabbit (author's transl)].
The effects of immunization with inactivated B. pertussis were studied in the rabbit using enteral (oral and via suppositories) and parenteral immunization routes. The rise in agglutinating and complement-binding immunoglobulins in the rabbit serum was about equal following immunization by suppository and parenteral administration, but the demonstration of local immunity (immunoglobulins reacting with B. pertussis in salive) by immunofluorescence methods was observed only in the group immunized with enterally-administered B. pertussis.
D000284:Administration, Oral; D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis; D007273:Injections, Intramuscular; D010567:Pertussis Vaccine / Q000008:administration & dosage*; D011817:Rabbits; D012463:Saliva / Q000032:analysis; D013488:Suppositories; D014917:Whooping Cough / Q000517:prevention & control*
D000942:Antigens, Bacterial; D010567:Pertussis Vaccine; D013488:Suppositories
Verleich der Wirksamkeit von parenteraler und enteraler Pertussisimmunisierung bei Kaninchen.