Fractional flux rates of Nt-methylhistidine in skin and gastrointestine: the contribution of these tissues to urinary excretion of Nt-methylhistidine in the rat.
1. Fractional flux rates of Ntau-methylhistidine (3-methylhistidine; Me-His) of skin and gastrointestine were measured by administering [methyl-3H]methionine to rats. 2. The results showed that the contribution of these tissues to urinary excretion of Me-His was at least 16-6%. This means that when fractional catabolic rates of myosin and actin were estimated from urinary excretion of Me-His, the part of Me-His derived from skin and gastrointestine should not be neglected.
D000818:Animals; D004064:Digestive System / Q000378:metabolism*; D006639:Histidine / Q000031:analogs & derivatives*; D008297:Male; D008715:Methionine / Q000378:metabolism; D008762:Methylhistidines / Q000378:metabolism* / Q000652:urine; D009132:Muscles / Q000378:metabolism; D051381:Rats; D012867:Skin / Q000378:metabolism*
D008762:Methylhistidines; D006639:Histidine; D008715:Methionine