Fusing human rod outer segments from an eye enucleated for choroidal melanoma.
In the retina from an eye enucleated for choroidal melanoma apposed rod outer segments were seen by transmission electron microscopy to be fusing together in groups by the confluence of their plasma membranes and the formation of cytoplasmic bridges between adjacent outer segments. These fusions were seen in areas distant from the melanoma but where the retina was not normal in appearance.
D002462:Cell Membrane / Q000648:ultrastructure; D002830:Choroid Neoplasms / Q000473:pathology*; D003593:Cytoplasm / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008545:Melanoma / Q000473:pathology*; D008875:Middle Aged; D010786:Photoreceptor Cells / Q000473:pathology* / Q000648:ultrastructure; D012164:Retinal Diseases / Q000473:pathology