title: Testosterone and persistence in mice.
abstract: In view of previous studies showing that testosterone increases persistence of food searching in chicks, a single factorially-designed experiment was carried out to investigate whether a similar phenomenon occurs in male mice. Using a runway test, it was found that testosterone, injected into castrated mice, did increase persistence. It was also shown that intact males resembled more the testosterone-injected than control-injected castrates, and that females resembled neither intact males nor either group of castrates. A larger number of training trials was found to affect feeding latencies in a similar way to testosterone. Comparison of two strains differing in emotional reactivity (BALB/c and Porton) showed differences consistent with their reactivity levels.
mesh_terms: D000818:Animals; D001288:Attention / Q000187:drug effects; D001522:Behavior, Animal / Q000187:drug effects*; D002369:Castration; D005247:Feeding Behavior / Q000187:drug effects; D005260:Female; D008297:Male; D051379:Mice; D012737:Sex Factors; D013739:Testosterone / Q000494:pharmacology*
chemical_list: D013739:Testosterone