title: [Determination of the insulin antibody titre in severe form of diabetes mellitus].
abstract: The blood serum binding capacity was studied in 20 patients suffering from diabetes mellitus given no insulin and in 67 patients with a severe form of diabetes mellitus treated with insulin. There proved to be a reverse relationship between the duration of insulin therapy and the insulin antibody titre. There was also a reverse relationship between the patient's age and the serum insulin-binding capacity. The dose of insulin administered failed to influence the level of insulin antibodies circulating in the organism.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000917:Antibody Formation; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000276:immunology*; D005260:Female; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D007330:Insulin Antibodies / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D011972:Receptor, Insulin
chemical_list: D007328:Insulin; D007330:Insulin Antibodies; D011972:Receptor, Insulin
vernacular_title: Opredelenie antitel k insulinu u bol'nykh s tiazheloĭ formoĭ sakharnogo diabeta.