title: Bilateral absence of the kidneys and ureters. Three cases reported in one family.
abstract: Three infant boys with bilateral absence of the kidneys and hypoplasia of the lungs are described. Two of the infants were brothers and the third was a first cousin. They were born to 2 sisters whose husbancs were unrelated to their wives and to each other. None of the parents had renal problems. The occurrence of this syndrome in 2 male sibs is suggestive of an autosomal recessive inheritance pattern which has been previously described. An additional male first cousin born to the mother's sister is sugesstive of sex-linked inheritance for this particular family, an inheritance pattern not previously described.
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics*; D005808:Genes, Recessive; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities*; D008168:Lung / Q000002:abnormalities; D008297:Male; D010375:Pedigree; D012730:Sex Chromosomes; D014513:Ureter / Q000002:abnormalities*