Crosslinking profiles of elastin from anatomically defined regions of the lung.
Elastin was isolated and purified by a procedure which sequentially removed lipids, collagen, structural glycoproteins and the microfibrillar proteins. Crosslinking profiles were obtained by column chromatography either after reduction with 3[H]NaBH4 or after reaction with 14[C]NaCN and NH3. Examination of the crosslinking profiles of the elastins from various tissue regions revealed differences in the type, distribution and quality of crosslinks.
D000818:Animals; D001980:Bronchi / Q000032:analysis; D002417:Cattle; D003895:Desmosine; D004549:Elastin; D008168:Lung / Q000032:analysis*; D010084:Oxidation-Reduction; D010994:Pleura / Q000032:analysis; D014132:Trachea / Q000032:analysis
D003895:Desmosine; D004549:Elastin