title: Infarct size and exercise capacity after myocardial infarction.
abstract: Estimation of infarct size from serum creatine phosphokinase elevations of 22 acute myocardial infarction (AMI) patients was compared to their functional exercise capacity determined on a bicyle ergometer. Eleven of these patients entered a controlled exercise program for 3-4 mo and were subsequently retested. Aerobic power of the exercise group increased significantly (mean +- SE 1.42 +- 0.5 met) and was also significantly greater than an unpaired control group tested the same number of months after infarct. Patients grouped 2.5-4.5 mo post-AMI demonstrated a correlation between aerobic power and estimated infarct size (r = -0.68, n = 15). This correlation was higher (r = -0.84, n = 11) after 3-4 mo of a controlled exercise program.
mesh_terms: D003402:Creatine Kinase / Q000097:blood; D004562:Electrocardiography; D005080:Exercise Test; D005081:Exercise Therapy; D006339:Heart Rate; D006801:Humans; D009203:Myocardial Infarction / Q000201:enzymology / Q000378:metabolism* / Q000534:rehabilitation; D010101:Oxygen Consumption; D013997:Time Factors
chemical_list: D003402:Creatine Kinase