title: Results of HBsAg testing of AABB-CAP survey samples.
abstract: Participants in the AABB-CAP HBsAg Survey Program and the Comprehensive Blood Bank Survey currently use radioimmunoassay (RIA) as the primary test for hepatitis B surface antigen (HBsAg). In changing from counterimmunoelectrophoresis (CEP) to RIA, participants have maintained a high degree of proficiency, detecting 99.1% of all reactive samples. Both RIA and reversed passive hemagglutination (RPHA) show greater sensitivity than the second-generation methods. Proficiency with RPHA has been variable because of the occurrence of false-positive reactions and difficulty in detecting some samples with RIA ratios between 2.1 and 7.0.
mesh_terms: D019411:Clinical Laboratory Techniques / Q000592:standards; D003378:Counterimmunoelectrophoresis; D006386:Hemagglutination Tests; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D008722:Methods; D011786:Quality Control; D011863:Radioimmunoassay; D014481:United States
chemical_list: D006514:Hepatitis B Surface Antigens