A disease in dogs resembling human subcorneal pustular dermatosis.
A pustular eruption similar to subcorneal pustular dermatosis of man occurred in 10 dogs. The disease was characterized by pustules of the trunk, which ruptured to form annular or gyrate lesions with irregular, scaling borders. Biopsies revealed subcorneal pustules with occasional acantholytic cells. All 10 dogs improved after daily administration of diaminodiphenylsulfone (dapsone).
D000818:Animals; D003622:Dapsone / Q000627:therapeutic use; D003872:Dermatitis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D003876:Dermatitis, Atopic / Q000175:diagnosis / Q000662:veterinary; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D004285:Dogs; D005260:Female; D007428:Intradermal Tests; D008297:Male; D012867:Skin / Q000473:pathology
D003622:Dapsone