[Is there any evidence that the maternal HPL serum-concentration is of prognostic value in cases of threatened abortion? (author's transl)].
The mean values of the maternal HPL are significantly decreased in cases of threatened abortion from the 10th to the 16th week post menstruation. But the HPL concentration is only of prognostic value after the 13th week because only after that time the HPL concentration is significantly decreased in cases with following abortion. The common therapy with gestagens or with a combination of estrogens and gestagens has no influence of the mean HPL concentrations. For the first time it could be shown an influence of an exogen estrogen-gestagen combination on the individual values of HPL serum-concentrations.
D000033:Abortion, Threatened / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D004958:Estradiol / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006908:Hydroxyprogesterones / Q000627:therapeutic use; D010928:Placental Lactogen / Q000097:blood*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011372:Progestins / Q000494:pharmacology / Q000627:therapeutic use; D011379:Prognosis
D006908:Hydroxyprogesterones; D011372:Progestins; D004958:Estradiol; D010928:Placental Lactogen
Besitzt die mütterliche HPL-Serumkonzentration beim Abortus imminens eine prognostische Aussage?