title: Mitochondrial DNA synthesis in adenovirus type 2-infected HeLa cells.
abstract: Mitochondrial DNA synthesis in adenovirus type 2-infected HeLa cells was measured at various times from 0 to 24 h postinfection. Although viral infection effectively turned off host chromosomal DNA synthesis, mitochondrial DNA synthesis was not inhibited. These findings indicate a dissociation between the regulation of host and mitochondrial DNA synthesis after infection with adenovirus type 2.
mesh_terms: D000260:Adenoviruses, Human / Q000254:growth & development* / Q000378:metabolism; D002499:Centrifugation, Density Gradient; D004261:DNA Replication; D004272:DNA, Mitochondrial / Q000096:biosynthesis*; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D004279:DNA, Viral / Q000096:biosynthesis; D006367:HeLa Cells / Q000378:metabolism*; D014779:Virus Replication
chemical_list: D004272:DNA, Mitochondrial; D004273:DNA, Neoplasm; D004279:DNA, Viral