[Factors influencing particle measurement of aerosols and their retention in the lung].
The dimensional characteristics of the particles of an aerosol depend on the means used for producing them. Mechanical spray and ultrasonic dispersion give polydispersed particles. On the other hand, centrifugal atomization produces a monodispersed aerosol. Particle retention in the lung system depends on the particle diameter. In addition, retention varies according to the respiratory characteristics: it is minimal for about 15 inspirations per minute. Using iron-59 labeled particles, it was shown that the degree of retention varies considerably from one individual to the other and accessibility to the depths of the lungs is decreased under the effect of certain lesions. Bronchial retention appears to be increased in smokers.
D000336:Aerosols; D006801:Humans; D008168:Lung / Q000502:physiology*; D008722:Methods; D010316:Particle Size; D012907:Smoking / Q000503:physiopathology; D014465:Ultrasonics
D000336:Aerosols
Facteurs influencçant la granulométrie des aérosols et leur rétention dans le poumon