Electroretinographic changes and choroidal defects in a case of central retinal artery occlusion.
A 62-year-old white woman with hypertensive diabetes had central retinal artery occlusion of her right eye. Serial electroretinographic (ERG) studies demonstrated reversible changes in the scotopic components but permanent reduction of the photopic b-wave. Serial simultaneous fluorescein and indocyanine green angiographic studies demonstrated a perfusion defect in the choroid involving part of the macula which subsided after reopening the retinal circulation. Differential hypoxic susceptibility of the ERG photopic and scotopic b-waves was demonstrated, and changes in the patient's retinal tissue oxygenation were postulated on the basis of retinal and choroidal angiographic studies performed during and after central retinal artery occlusion to account for the observed changes in serial ERGS.
D000221:Adaptation, Ocular; D002829:Choroid / Q000098:blood supply*; D003251:Constriction, Pathologic / Q000503:physiopathology; D003623:Dark Adaptation; D048909:Diabetes Complications; D004596:Electroretinography; D005071:Evoked Potentials; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D000860:Hypoxia / Q000503:physiopathology; D008027:Light; D008875:Middle Aged; D012160:Retina / Q000503:physiopathology*; D012161:Retinal Artery / Q000503:physiopathology*; D012171:Retinal Vessels / Q000503:physiopathology; D014603:Uveal Diseases / Q000503:physiopathology; D014652:Vascular Diseases / Q000503:physiopathology