[Effect of acetycholine chloride and chlorocholine chloride on the resting potential and membrane resistance of identified mollusk A and B neurons].
Chlorcholine chloride (CCC) the molecule of which has no other group, characteristic of acetylcholine (Ach), causes an effective cholinomimetic action on the surface membrane of the mollusc neurons A and B. As the concentration of Ach and CCC increases from 10(-6) to 10(-3) M the resting potential (RP) and the membrane resistance (R) of the neuron A first increases then decreases. The increase of Ach and CCC concentration causes in the neuron B only a decrease of the above mentioned parameters. The data point to the necessity of improving the ideas about the structure of cholinoreceptors and mechanism of cholinoreceptor-cholinomimetic interaction.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D002794:Choline / Q000031:analogs & derivatives*; D004553:Electric Conductivity; D008564:Membrane Potentials / Q000187:drug effects*; D008974:Mollusca / Q000166:cytology*; D009474:Neurons / Q000187:drug effects*; D011950:Receptors, Cholinergic / Q000187:drug effects
D011950:Receptors, Cholinergic; D002794:Choline; D000109:Acetylcholine
Deĭstvie atsetilkholinkhlorida na potentsial pokoia i soprotivlenie membrany identifitsirovannykh neĭronov A i B molliuska.