title: Immunity to Trichinella spiralis. VII. Resistance stimulated by the parenteral stages of the infection.
abstract: In three experiments mice were given three intravenous injections of Trichinella spiralis newborn larvae produced in vitro. Following a challenge infection of newborn larvae the mice were shown to be on the average 85% resistant i.e., only 15% of the challenge larvae developed to encysted muscle stage larvae in these mice; when the challenge consisted of normal muscle larvae administered per os, the mice were 51% resistant. Neither the number nor longevity of adult worms in the intestines was affected by this immunization procedure.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D005260:Female; D007109:Immunity; D007275:Injections, Intravenous; D007422:Intestines / Q000469:parasitology; D007814:Larva; D051379:Mice; D014234:Trichinella; D014235:Trichinellosis / Q000276:immunology* / Q000469:parasitology