Primary thrombosis of pulmonary artery in a child with tetralogy of Fallot.
A 34-month-old child with tetralogy of Fallot developed an acute, primary thrombosis of the pulmonary trunk. A greatly increased haematocrit was most probably a predisposing factor. An unusual postmortem finding was the large number of extremely dilated myocardial capillaries. In a review of a series of 394 consecutive necropsy cases with many kinds of cardiac anomalies, there was only one case (a 28-year-old man) with occluding thrombus formation in the pulmonary artery. This case also belonged to the Fallot group but a subacute glomerulonephritis seemed to be the major cause of death.
D002196:Capillaries / Q000473:pathology; D002675:Child, Preschool; D003331:Coronary Vessels / Q000473:pathology; D006400:Hematocrit; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D011655:Pulmonary Embolism / Q000150:complications*; D013771:Tetralogy of Fallot / Q000150:complications*