[Changes in the size of the nuclei of adrenal cortex cells of rats after repeated physical stress].
Nuclear volumes of cells in rat adrenal cortex were measured. The rats were forced to swim during one month for 3 hours a day. During the experiment, the extension of nuclear hypetrophy in the external zona fasciculata underwent some phasic changes, phases being as follows: 1) increase in hypertrophy up to the maximum (2nd and 5th days of experiment); 2) the stability of hypertrophy close to the maximum (12th, 18th and 24th days), and the decrease in hypertrophy (30th day). The phases are assumed to correspond, respectively, to stages of alarm reaction, resistance and exhaustion caused by chronic stress. The increased nuclear volume of cells was also observed in the internal zona fasciculata. The discrepancy between nuclear volumes of zona reficularis in the experiment and in the control was statistically insignificant.
D000302:Adrenal Cortex / Q000648:ultrastructure*; D000311:Adrenal Glands / Q000648:ultrastructure*; D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure*; D006984:Hypertrophy; D008297:Male; D051381:Rats; D013312:Stress, Physiological / Q000473:pathology*; D013997:Time Factors
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