Hypokalemia and cardiac arrhythmia associated with prostaglandin-induced abortion.
Experience with 1 patient undergoing second trimester therapeutic abortion induced by prostaglandin F2alpha administration is described. Serious hypokalemia in association with cardiac arrhythmia followed intraamniotic administration of the drug. Further observations on a group of normal subjects receiving prostaglandin injections for induction of abortion showed a small but significant serum hypokalemia after treatment.
D000032:Abortion, Therapeutic / Q000009:adverse effects; D000328:Adult; D001145:Arrhythmias, Cardiac / Q000097:blood / Q000139:chemically induced*; D004562:Electrocardiography; D004573:Electrolytes / Q000097:blood; D005260:Female; D006801:Humans; D007008:Hypokalemia / Q000097:blood / Q000139:chemically induced*; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011460:Prostaglandins F / Q000008:administration & dosage / Q000009:adverse effects; D011465:Prostaglandins, Synthetic / Q000008:administration & dosage / Q000009:adverse effects*
D004573:Electrolytes; D011460:Prostaglandins F; D011465:Prostaglandins, Synthetic