[Modification of the properties of drugs combined with polymers. II].
In the second part of the paper there have been discussed the works on modification of drugs properties when coupled with polymers in terms of covalent links. It was proved on a number of cases that chemical bonds of specified drugs and polymers allows to increase the durability and effective action of these remedies, to decrease the toxicity, to increase the solubility and immunity against ferments and, moreover, enable the advantageous disposal of these substances in particular organs.
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004355:Drug Stability; D008722:Methods; D008970:Molecular Weight; D010118:Oxytetracycline / Q000008:administration & dosage; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000378:metabolism*; D011108:Polymers / Q000378:metabolism*; D013329:Structure-Activity Relationship; D014116:Toxicology
D004364:Pharmaceutical Preparations; D011108:Polymers; D010118:Oxytetracycline
Modifikatsiia svoĭstv lekarstvennykh veshchestv putem prisoedineniia ikh k polimeram. Chast' II.