[Influence of long term neuroleptic therapies on the function of the peripheral motoric neuron? (author's transl)].
In electroneurographic and electromyographic examinations of 37 patients who had taken neuroloptic drugs for many years a delay in the conduction velocity of the ulnar nerve was found in one case, of the fibular nerve in five cases. Spontaneous electrical activity was not observed in any case. Deviations from the mean of the action potential were found more frequently, however less markedly than in alcoholics. It is suggested that these small changes are caused by the slight anticholinergic action of major tranquilizers.
D000200:Action Potentials / Q000187:drug effects; D006801:Humans; D009046:Motor Neurons / Q000187:drug effects*; D009431:Neural Conduction / Q000187:drug effects; D012559:Schizophrenia / Q000188:drug therapy / Q000503:physiopathology; D013997:Time Factors; D014149:Tranquilizing Agents / Q000494:pharmacology* / Q000627:therapeutic use
D014149:Tranquilizing Agents
Chronischer Neuroleptikagebrauch und Schäden im Bereich des peripheren motorischen Neurons.