Interaction of new derivatives of daunorubicin and adriamycin with DNA.
The interaction of a number of new derivatives of the antitumour antibiotics daunorubicin and adriamycin with calf-thymus DNA has been studied by equilibrium dialysis and low-shear viscosimetry. The results are interpreted in terms of structure of the compounds, also by examining molecular stereomodels.
D000818:Animals; D002417:Cattle; D004247:DNA / Q000378:metabolism*; D003630:Daunorubicin / Q000031:analogs & derivatives / Q000378:metabolism*; D004317:Doxorubicin / Q000031:analogs & derivatives / Q000378:metabolism*; D013950:Thymus Gland / Q000378:metabolism; D014783:Viscosity
D004317:Doxorubicin; D004247:DNA; D003630:Daunorubicin