title: Radiation therapy of squamous carcinoma of the floor of mouth and the lower alveolar ridge.
abstract: Treatment for 139 patients with squamous carcinomas in the floor of mouth and the lower alveolar ridge, which accounted for one-third of all patients with intra-oral cancer, are evaluated and classified after UICC and AJC's TNM recommendations retrospectively, for cancer staging and End Result Reporting. The figures include 50% women with tumours and in lower alveolar ridge. Two treatment schemes: external cobalt irradiation and external irradiation in combination with intra-oral radium-mould have been used in spite of primary bone invasion. 30% had remnant tumours and 22% recurred locally. 70% of the recurrences were discovered within a year after treatment. The total crude survival for all patients was 32%, identical for both groups. Lymph node metastases lower the survival significantly. Less than one-third had difficulties in mucous healing after treatment and 9% developed osteoradionecrosis, but only half of those patients had symptoms.
mesh_terms: D000368:Aged; D000539:Alveolar Process; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor; D009062:Mouth Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D011878:Radiotherapy / Q000009:adverse effects