title: Renal function after high-dose urography in patients with chronic renal insufficiency.
abstract: Renal function was assessed by frequent recordings of Ccr and serum creatinine in 22 patients with chronic renal failure before and after high-dose urography. Urography was followed by a significant, moderate and transient decrease in Ccr which was maximal on the second day; at the same time a significant increase in serum creatinine was observed which was maximal on the fourth day after urography. In all but two patients, Ccr and serum creatinine returned to pre-urographic levels within the next two weeks. Possible causes of the deleterious effects of the contrast media on the kidneys are discussed.
mesh_terms: D003404:Creatinine / Q000378:metabolism* / Q000652:urine; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000652:urine; D008297:Male; D011829:Radiation Dosage; D014567:Urography
chemical_list: D003404:Creatinine