[Lipid makeup of the initial and selected strains of Actinomyces levoris and Streptoverticillium mycoheptinicum in the process of antibiotic synthesis].
The study of the lipid composition showed that the rate of the changes in the fatty acid composition of neutral lipids and phospholipids in the selected strains was higher than that in the initial strains. The medium composition had the decisive effect on the fractional and fatty acid spectrum of the mycelium lipids. When the antibiotic-producing organisms were grown on the synthetic medium the phospholipids were the predominating fractions (70--90 per cent of the total lipids), while with the use of organic medium they amounted only to 30--40 per cent. The data were evident of complex correlation between the synthesis of fatty acids and polyenic antibiotics, i.e. levorin and mycoheptin.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D005227:Fatty Acids / Q000032:analysis; D008055:Lipids / Q000032:analysis*; D010743:Phospholipids / Q000032:analysis; D011090:Polyenes / Q000096:biosynthesis; D012641:Selection, Genetic; D013302:Streptomyces / Q000032:analysis* / Q000378:metabolism; D013306:Streptomycetaceae / Q000032:analysis* / Q000378:metabolism; D013997:Time Factors
D000900:Anti-Bacterial Agents; D005227:Fatty Acids; D008055:Lipids; D010743:Phospholipids; D011090:Polyenes
Sostav lipidov iskhodnykh i selektsionirovannykh shtammov Actinomyces levoris i Streptoverticillium mycoheptinicum v protsesse sinteza antibiotikov