title: Selective cell loss in the lateral geniculate nucleus of adult cats following binocular lid suture.
abstract: Two weeks of binocular lid suture in adult cats caused selective cell loss in lamina A1 of the lateral geniculate nucleus. The loss was manifested as a shift in the latency distribution of LGN cell responses to optic chiasm shock. Proportionately fewer LGN cells with slowly conducting retinal afferents (X-cell range) were in evidence following binocular suture. This change was observed only in lamina A1 while laminae A and C retained normal latency distributions. These observations confirm and extend recent reports of the susceptibility of adult cat visual system to environmental modification.
mesh_terms: D000818:Animals; D001766:Blindness / Q000503:physiopathology*; D002415:Cats; D002470:Cell Survival; D004558:Electric Stimulation; D005071:Evoked Potentials; D005829:Geniculate Bodies / Q000502:physiology*; D009431:Neural Conduction; D009897:Optic Chiasm / Q000502:physiology; D014795:Visual Pathways