Limitation of abduction of hips in the newborn. Is it a clinical sign or a phenocopy of congenital hip dislocation?
Until recently the possibility of a connection between maternal thyroid disorders and congenital hip pathology in the newborn has not been given any attention. However, from this study it is evident that there is a close relationship between maternal thyroid disorders and limitation of abduction of the hips in the newborn. The histological findings are suggestive of a neonatal thyrotoxic myopathy or periodic paralysis which might give rise to an error in muscle balance around the hips. The high proportion of affected children without a family history of congenital hip dislocation suggests that genetic factors have in the past been overemphasized.
D000328:Adult; D005260:Female; D006618:Hip Dislocation, Congenital / Q000209:etiology / Q000235:genetics / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009132:Muscles / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications; D013959:Thyroid Diseases / Q000150:complications; D013960:Thyroid Function Tests