Hypothyroidism due to ectopy in siblings.
Two families each had two siblings with hypothyroidism due to ectopy and hypoplasia of the thyroid. A genetic factor controlling normal thyroid development and descent may be responsible, and the importance of plasma thyroid-stimulating hormone estimation in borderline hypothyroid cases is emphasized. We suggest screening of siblings of patients with ectopic thyroid for hypothyroidism.
D002675:Child, Preschool; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000235:genetics*; D007223:Infant; D008297:Male; D013961:Thyroid Gland / Q000002:abnormalities*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
D013972:Thyrotropin; D013974:Thyroxine