[Effect of carboxylation reactions stimulation on intensity of 14CO2 fixation in rabbits with posthemorrhage anemia and on repairing of blood components in human anemia].
The repair processes with posthemorrhage anemia were studied in experiment and clinics as affected by the preparation (sodium bicarbonate and magnesium, manganese and zinc sulphates in a ratio of 25:5:0.1:0.1) which stimulates the carboxylation reactions in the organism. Stimulation of the carboxylation reactions in the rabbits with experimental posthemorrhage anemia increases the intensity of 14CO2 carbon transformation of organic compounds in the tricarboxylic cycle, intensifies 14C incorporation into the liver, kidneys, spleen and marrow proteins as well as into serum albumin and globulins. Under clinical conditions stimulation of CO2 fixation with the preparation favours an intensified formation of the red series cells and biosynthesis of hemoglobin and serum proteins as well as the repair of their disturbed balance in patients with posthemorrhage anemia. The content of magnesium in blood plasma normalizes.
D000328:Adult; D000740:Anemia / Q000097:blood / Q000209:etiology / Q000378:metabolism*; D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology; D001798:Blood Proteins / Q000096:biosynthesis; D001815:Bloodletting; D002245:Carbon Dioxide; D002952:Citric Acid Cycle; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006410:Hematopoiesis; D006801:Humans; D008274:Magnesium / Q000494:pharmacology; D008297:Male; D008345:Manganese / Q000494:pharmacology; D008875:Middle Aged; D014176:Protein Biosynthesis; D011817:Rabbits; D012964:Sodium / Q000494:pharmacology; D015032:Zinc / Q000494:pharmacology
D001639:Bicarbonates; D001798:Blood Proteins; D002245:Carbon Dioxide; D008345:Manganese; D012964:Sodium; D008274:Magnesium; D015032:Zinc
Vpliv stimuliatsii karboksiliuvannia na intensivnist' fiksatsii 14CO2 u kroliv z postgemoragichnoiu anemieiu ta na vidnovlennia komponentiv krovi u liudeĭ za anemii.