title: [Effect of long-term space flight on protein biosynthesis in different rat tissues and organs].
abstract: Protein synthesis in the heart, lungs, liver, pancreas, thymus, kidneys, skeletal muscles and testes of the 22-day Cosmos-605 flight and synchronous rats was studied with the aif of 14C-amino acid incorporation. On the 2nd postflight day both flight and synchronous rats showed an increased synthesis of heart sarcoplasmatic proteins. On the 26th postflight day the rate of incorporation was normal. On the 2nd and 26th days the synthesis of myofibrillar proteins in the m. quadriceps femoris was inhibited in flight animals postflight day the rate of incorporation was normal. On the 2nd and 26th days the syn-only. On the 2nd and 26th days the liver of the flight and synchronous rats showed qualitatively similar changes in protein metabolism of subcellular structures. No changes in the protein synthesis of other organs tested were detected.
mesh_terms: D000818:Animals; D007930:Leucine / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009124:Muscle Proteins / Q000096:biosynthesis; D009132:Muscles / Q000378:metabolism; D009928:Organ Specificity; D014176:Protein Biosynthesis; D051381:Rats; D013026:Space Flight; D013997:Time Factors
chemical_list: D009124:Muscle Proteins; D007930:Leucine
vernacular_title: Vliianie dlitel'nogo kosmicheskogo poleta na biosintez belkov razlichnykh organov i tkaneĭ krys.