title: Anthelmintic dihydroquinoxalino[2,3-b]quinoxalines.
abstract: A series of dihydroquinoxalino[2,3-b]quinoxalines was synthesized and tested for anthelmintic activity in a model assay. The most promising compound, 5,12-diacetyl-5,12-dihydroquinoxalino[2,3-b]quinoxaline, was orally effective in sheep at a dose of 200 mg/kg against a broad range of helminths.
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000138:chemical synthesis* / Q000627:therapeutic use; D011810:Quinoxalines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000627:therapeutic use; D012756:Sheep; D014252:Trichostrongyloidiasis / Q000188:drug therapy
chemical_list: D000871:Anthelmintics; D011810:Quinoxalines