[Role of the dopaminergic structures of the kidney in the renal effects of euphyllin].
Reserpine and galoperidol are shown to exercise blocking effect with regard to the diuretic and saluretic action of the xanthine-euphylline. Galoperiod prevented an accretion of the total renal blood flow induced by euphylline. Preliminary introduction to rats of alpha-methyl-DOPA and 1-DOPA abolished the blocking action of reserpine on the renal effects of euphylline. The renal influence of euphylline is mediated through dopamine-ergic structures, which are non-identical to adrenostructures. Dopamine is not merely a precursor of norepinephrine and epinephrine, but performs functions of its own in the organism.
D000628:Aminophylline / Q000494:pharmacology*; D000818:Animals; D004231:Diuresis / Q000187:drug effects; D005260:Female; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006220:Haloperidol / Q000494:pharmacology; D007668:Kidney / Q000187:drug effects*; D007980:Levodopa / Q000494:pharmacology; D008297:Male; D008750:Methyldopa / Q000494:pharmacology; D009318:Natriuresis / Q000187:drug effects; D011188:Potassium / Q000652:urine; D051381:Rats; D011954:Receptors, Dopamine / Q000187:drug effects*; D012110:Reserpine / Q000494:pharmacology
D011954:Receptors, Dopamine; D000628:Aminophylline; D007980:Levodopa; D008750:Methyldopa; D012110:Reserpine; D006220:Haloperidol; D011188:Potassium
Rol' dofaminergicheskikh struktur  pochki v renal'nykh éffektakh éufillina.