[Agranulocytosis after antiarrhythmic therapy with ajmalin (author's transl)].
A case of agranulocytosis (min. leucocyte count 980/mm3) after 4 weeks of treatment with an ajmalin derivate is reported. Recovery could be achieved by taking away the antiarrhythmic drug. It appears that these agranulocytoses only happen after a dosage of more than 300 mg/die, and that they have an intermediate position between allergic and toxic agranulocytosis (phenothiazine type).
D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced*; D000404:Ajmaline / Q000009:adverse effects* / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000188:drug therapy; D001282:Atrial Flutter / Q000188:drug therapy; D006801:Humans; D008297:Male
D000404:Ajmaline
Agranulozytose nach Antiarrhythmikatherapie mit Ajmalin.