Metabolism of labeled fatty ozonides administrated intravenously in rats.
The distribution and metabolism of uniformly labeled fatty ozonides administrated intravenously in rats were studied. More than 90% of radioactivity was recovered in the lung tissue even 4 to 8 hr after injection of labeled ozonides, and approximately 60% of total radioactivity incorporated into the lung tissue remained as fatty ozonides. A slight amount of radioactivity, which was mainly incorporated into phospholipid and triglyceride, was recovered in liver and kidney.
D000818:Animals; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage / Q000378:metabolism*; D007275:Injections, Intravenous; D007668:Kidney / Q000378:metabolism; D008041:Linoleic Acids / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism*; D010126:Ozone / Q000008:administration & dosage / Q000378:metabolism*; D051381:Rats
D005231:Fatty Acids, Unsaturated; D008041:Linoleic Acids; C015211:fatty ozonides; D010126:Ozone