title: Serologic identification of hemopoietic progenitor cell antigens common to mouse and man.
abstract: An immunologic approach to the identification of human hemopoietic stem cell antigens has yielded two types of antisera. Both recognize antigens on hemopoietic progenitors which are identical or cross-reactive with determinants on sperm, brain, and, across the species barrier, with murine hemopoietic stem cells (CFU-S). The first antiserum was the result of an autoimmune reaction in a post-vasectomy patient. The second was produced in rabbits after injection of human brain cells.
mesh_terms: D000818:Animals; D000941:Antigens; D001323:Autoantibodies; D001426:Bacterial Proteins; D001921:Brain / Q000276:immunology; D002478:Cells, Cultured; D003429:Cross Reactions; D006412:Hematopoietic Stem Cells / Q000276:immunology*; D006801:Humans; D007106:Immune Sera; D007074:Immunoglobulin G / Q000302:isolation & purification; D008297:Male; D051379:Mice; D013045:Species Specificity; D013094:Spermatozoa / Q000276:immunology; D013154:Spleen / Q000166:cytology; D013210:Staphylococcus / Q000276:immunology; D014659:Vasectomy
chemical_list: D000941:Antigens; D001323:Autoantibodies; D001426:Bacterial Proteins; D007106:Immune Sera; D007074:Immunoglobulin G