title: Antitumor effect of seaweeds. II. Fractionation and partial characterization of the polysaccharide with antitumor activity from Sargassum fulvellum.
abstract: An almost purified antitumor polysaccharide fraction (SFPP) was obtained by fractional precipitation with ethanol from hot-water extract of Sargassum fulvellum. The fraction showed remarkable tumor-inhibiting effect against sarcoma-180 implanted subcutaneously in mice. The results of chemical and physical analyses suggested that the active substance may be either a sulphated peptidoglycuronoglycan or a sulphated glycuronoglycan.
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis* / Q000302:isolation & purification; D008297:Male; D051379:Mice; D011134:Polysaccharides / Q000032:analysis* / Q000302:isolation & purification; D012510:Sarcoma 180 / Q000188:drug therapy; D012624:Seaweed / Q000032:analysis*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D011134:Polysaccharides