title: Chromatin very small angle neutron scattering: further evidence for a 30 nm diameter super coil in dilute solutions.
abstract: Intact chromatin, chromatin minus histone H1, and nuclease digestion fragments have been studied by very small angle neutron scattering. The results are not consistent with a straight chain of nucleosomes and require the presence of a higher order coiling in monovalent salt solutions. The data are interpretable by a structure having a cross section radius of gryration of 8.5 +/- 1 nm, which suggests an outer diameter for a coil of nucleosomes of 27 +/- 3 nm.
mesh_terms: D000818:Animals; D002417:Cattle; D002843:Chromatin / Q000648:ultrastructure*; D004247:DNA; D003851:Deoxyribonucleases; D006657:Histones; D009502:Neutrons; D009690:Nucleic Acid Conformation; D051381:Rats; D012542:Scattering, Radiation
chemical_list: D002843:Chromatin; D006657:Histones; D004247:DNA; D003851:Deoxyribonucleases