title: Biological and phytochemical investigations of Dianthus barbatus cv. "China Doll" (Caryophyllaceae).
abstract: From the aerial parts of Dianthus barbatus cv. "China Doll", two saponins (barbatosides A and B) were isolated and shown to have analgesic and anti-inflammatory activities. The aglycone of each saponin was identified as quillaic acid. The glycone of barbatoside A consisted of rhamnose, arabinose, fucose, xylose, galactose, glucose and one unidentified sugar; whereas the glycone of barbatoside B contained arabinose, fucose, xylose, mannose, galactose, glucose and three unidentified sugars. Astragalin, kaempferol-3-O-beta-D-sophoroside, D-pinitol and L-leucine were also isolated.
mesh_terms: D000085:Acetates; D000700:Analgesics / Q000302:isolation & purification; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000302:isolation & purification; D002241:Carbohydrates / Q000032:analysis; D002351:Carrageenan; D055598:Chemical Phenomena; D002621:Chemistry; D004353:Drug Evaluation, Preclinical; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D006614:Hindlimb; D051379:Mice; D009828:Oleanolic Acid / Q000031:analogs & derivatives*; D010946:Plants, Medicinal / Q000032:analysis*; D051381:Rats; D012503:Saponins / Q000302:isolation & purification* / Q000627:therapeutic use
chemical_list: D000085:Acetates; D000700:Analgesics; D000893:Anti-Inflammatory Agents; D002241:Carbohydrates; D012503:Saponins; D009828:Oleanolic Acid; D002351:Carrageenan