In vitro effects of streptomyces protease inhibitors on human kidney renin activity.
The effects of several low molecular streptomyces protease inhibitors on human kidney renin activity have been observed. This study shows that, in addition to pepstatin A, leupeptin, antipain, and SP-I also inhibit human renin activity in vitro.
D000804:Angiotensin II / Q000096:biosynthesis; D001426:Bacterial Proteins / Q000494:pharmacology*; D006801:Humans; D007668:Kidney / Q000201:enzymology*; D007700:Kinetics; D007976:Leupeptins / Q000494:pharmacology; D008970:Molecular Weight; D010436:Pepstatins / Q000494:pharmacology; D011480:Protease Inhibitors; D013302:Streptomyces; D000092502:Renin Inhibitors
D000804:Angiotensin II; D001426:Bacterial Proteins; D007976:Leupeptins; D010436:Pepstatins; D011480:Protease Inhibitors; D000092502:Renin Inhibitors