title: Reagents which inhibit disulphide bond formation stabilize human fibroblast interferon.
abstract: Fibroblast interferon may be stabilized against many inactivating influences by the addition of certain simple sulphydryl reagents. The use of such easily removable and relatively non-toxic stabilizers should help in the preparation and purification of fibroblast interferon for clinical use.
mesh_terms: D002460:Cell Line; D003545:Cysteine / Q000031:analogs & derivatives / Q000494:pharmacology; D004355:Drug Stability; D005347:Fibroblasts; D006801:Humans; D007372:Interferons / Q000096:biosynthesis / Q000494:pharmacology*; D008168:Lung / Q000196:embryology; D010421:Pentanoic Acids / Q000494:pharmacology; D013314:Stress, Mechanical; D013439:Sulfhydryl Reagents / Q000494:pharmacology*
chemical_list: D010421:Pentanoic Acids; D013439:Sulfhydryl Reagents; D007372:Interferons; D003545:Cysteine