title: [Degradation and residue dynamics of the anthelminthic 131J-rafoxanide in cattle blood, milk, meat and fat after various dosages].
abstract: Rafoxanide, labelled by 131J, was applied orally in oily solution to cattle, 2,4 and 12 mg/kg bodymass, resp. The halflifes of degradation in blood is depending on the dosage and is 7 days related to the therapeutical dosage of 5 mg/kg bodymass against Fasciola hepatica. Residues and halflifer in blood, milk, meat and fat are given, related to 131J in the chloroform extract. Rafoxanide does not show persistence following oral application to cattle.
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D002417:Cattle; D004305:Dose-Response Relationship, Drug; D006207:Half-Life; D007700:Kinetics; D008460:Meat; D008892:Milk / Q000378:metabolism; D011888:Rafoxanide / Q000097:blood / Q000378:metabolism*; D012457:Salicylamides / Q000378:metabolism*
chemical_list: D012457:Salicylamides; D011888:Rafoxanide
vernacular_title: Abbau und Rückstandsdynamik des Anthelminthikums 131J-Rafoxanid in Blut, Milch, Fleisch und Fett bei unterschiedlicher Dosierung am Rind.