Potentiation of radiation effects in hypoxic HeLa cells.
HeLa cells were irradiated with two doses of gamma rays: the first dose was delivered under hypoxic conditions and the second dose was delivered under oxygenated conditions. Increased inactivation of cellular proliferative capacity as a function of intervening time was obtained when hypoxic conditions were maintained between doses. Hypoxic protection from ionizing irradiation can be counteracted by manipulating postirradiation conditions.
D002455:Cell Division / Q000528:radiation effects; D002588:Cesium Radioisotopes; D005720:Gamma Rays; D006367:HeLa Cells / Q000528:radiation effects*; D010100:Oxygen
D002588:Cesium Radioisotopes; D010100:Oxygen