[Effect of bile acids and other surface-active substances on antidiuretic hormone regulation of epithelial membrane permeability].
Surfactants in low concentrations (1.10(-5) and 1.10(-4) g/ml) altered the action of the antidiuretic hormone on the permeability of the wall of frog urinary bladder. Anionogenic sodium cholate, nonionogenic twin-80 and cationoactive ethonium depressed the action of the antidiuretic hormone. Polyampholite eBM-4 enhanced the effect of the antidiuretic hormone. The effect of saponin depended on the concentration of the preparation. Of interest is a possibility of using the surfactants for influencing the mechanisms regulating water balance in the organism.
D000818:Animals; D001001:Anura; D002463:Cell Membrane Permeability / Q000187:drug effects*; D002793:Cholic Acids / Q000494:pharmacology; D004357:Drug Synergism; D006000:Glycocholic Acid / Q000494:pharmacology; D011136:Polysorbates / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage; D012503:Saponins / Q000494:pharmacology; D013501:Surface-Active Agents / Q000008:administration & dosage*; D001743:Urinary Bladder / Q000187:drug effects*; D014667:Vasopressins / Q000008:administration & dosage* / Q000037:antagonists & inhibitors
D002793:Cholic Acids; D011136:Polysorbates; D000644:Quaternary Ammonium Compounds; D012503:Saponins; D013501:Surface-Active Agents; D014667:Vasopressins; D006000:Glycocholic Acid
Vliianie zhelchnykh kislot i drugikh poverkhnostno-aktivnykh veshchestv na reguliatsiiu antidiureticheskim gormonom pronitsaemosti épitelial'nykh membran.