title: Methohexitone-induced convulsions in epileptics.
abstract: The risk of precipitating a convulsion in epileptic patients with methohexitone has been judged to vary widely. This article reports such complications arising during methohexitone-activated E.E.G. recording in a series of 48 epileptic patients from whom anticonvulsant medication was withheld. Two patients developed grand mal convulsions during induction with methohexitone 1-0%. Two others exhibited status epilepticus of the petit mal type and one of the myoclonic type, after stopping an infusion of 0-09% methohexitone. The specificity for methohexitone-induced convulsions in epileptics or crypto-epileptics is supported by a review of the literature.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D002648:Child; D004569:Electroencephalography; D004739:England; D004827:Epilepsy / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008723:Methohexital / Q000009:adverse effects*; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D008723:Methohexital