title: [Characteristics of the water-salt metabolism and functional state of the kidneys in members of the crew of the 1st "Saliut-4" expedition].
abstract: The paper presents the results of studying fluid-electrolyte metabolism and the renal function in A. A. Gubarev and G. M. Grechko after their 30-cay orbital flight. On the R + O day renal excretion of fluid, sodium, potassium and osmotically active subtances decreased. Renal excretion of calcium and magnesium postflight was higher than preflight. Similar, although better pronounced, changes were seen during provocative tests with a water load. One of the factors causing changes in the renal transport of electrolytes postflight could have been an alteration in the ionic composition of the serum, especially a decrease in the potassium concentration and an increase in the calcium and magnesium content. Disorders in the relationship between the function of osmo- and ion regulation systems and dissociation in the renal excretion of individual ions after the 30-day flight that were distinct during tests with a water load seem to be associated with metabolic changes during and after flight rather than with hemodynamic changes.
mesh_terms: D004231:Diuresis; D004326:Drinking; D004573:Electrolytes / Q000652:urine; D006801:Humans; D007668:Kidney / Q000502:physiology*; D012636:Secretory Rate; D013026:Space Flight; D013997:Time Factors; D014586:USSR; D014882:Water-Electrolyte Balance
chemical_list: D004573:Electrolytes
vernacular_title: Osobennosti vodno-solevogo obmena i funktsional'nogo sostoianiia pochek u chlenov ékipazha pervoĭ ékspeditsii "Saliut-4".