[Eosinophilic granulomatosis: a case report on a rarely found disease of the hypereosinophilic syndrome (author's transl)].
This ia a case report on a eosinophilic granulomatosis. This disease falls nunder the hypereosinophilic syndrome as well as the eosinophilic leukemia, the disseminated eosinophilic collagenosis, and the endocarditis fibroplastica parietalis Löffler. These diseases are characterized by cardiovascular, pulmonary, abdominal and cerebral symptoms. An increased number of eosinophilic granulocytes constitutes the obligatory hematologic feature. Eosinophilic infiltration and vasculitis especially of the small vessels in heart, lung, liver, spleen, lymphnodes, and cerebrum are typical pathological findings. The eosinophilic granulomatosis shows in addition extravascular granulomas with abundant eosinophilic granulocytes. It is assumed that the hypereosinophilic disorders result from the same basic disease. We would suggest to described this basic disease as allergic eosinophilic collagenosis. This term implies both the supposed etiology and the histologic localisation of the disorder.
D000328:Adult; D001344:Autopsy; D004803:Eosinophilic Granuloma / Q000473:pathology*; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D009206:Myocardium / Q000473:pathology; D013154:Spleen / Q000473:pathology
Die eosinophile Granulomatose. Ein seltenes Krankheitsbild aus Formenkreis des hypereosinophilen Syndroms.