Anaesthetic management of patients with phaeochromocytoma. A review of 102 cases.
A total of 102 patients with phaeochromocytoma who underwent surgery by the same team between 1964 and 1976 were allocated to three groups according to the anaesthetic protocol used: (1) balanced anaesthesia and control of hypotension with noradrenaline; (2) anaesthesia with halothane and replacement of blood volume; (3) neuroleptanalgesia (droperidol and phenoperidine) and replacement of blood volume. None of the patients in any of the three groups received adrenergic inhibitors before anaesthesia. Comparison of the results in the three groups revealed that the major factor responsible for reduction of operative mortality to almost zero was control of hypotension by replacement of blood volume rather than by the use of noradrenaline following resection of the tumour, whereas the type of anaesthetic agent used was of secondary importance.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000758:Anesthesia / Q000379:methods*; D000768:Anesthesia, General; D001145:Arrhythmias, Cardiac / Q000150:complications; D001810:Blood Volume; D002648:Child; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D007022:Hypotension / Q000150:complications; D008297:Male; D008875:Middle Aged; D009458:Neuroleptanalgesia; D010673:Pheochromocytoma / Q000150:complications / Q000601:surgery*; D011183:Postoperative Complications