Salmonella empyema as a complication in malignant pleural effusion.
Salmonella empyema in an immunologically compromised patient with malignant pleural effusion is described. Antimicrobial treatment was ineffective when given parenterally. Intrapleural administration of antibiotics resulted in a rapid rise of the antibacterial activity of the pleural fluid, leading to rapid clinical improvement and eradication of the infections.
D000230:Adenocarcinoma / Q000150:complications; D004653:Empyema / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010996:Pleural Effusion / Q000382:microbiology*; D012475:Salmonella / Q000187:drug effects / Q000302:isolation & purification; D012480:Salmonella Infections / Q000150:complications / Q000188:drug therapy; D013752:Tetracycline / Q000627:therapeutic use; D013964:Thyroid Neoplasms / Q000150:complications
D013752:Tetracycline