title: The stress-related emotional lability syndrome. 1. Definition, psychophysiological mechanisms and a pilot experience with Orap.
abstract: Patients suffering from stress-related emotional lability are in our modern life a common phenomenon. The diagnosis is difficult by the atypical symptoms (body complaints who are suggestive for a neurosis and becomes apparent on careful questioning revealing fear of failing, rigidity and similar character traits. Also, certain tests indicate increased fear of failing and the MMPI reveals high scores for psychiasthenia. Those patients starts from a high "baseline (endogenous) stress level. Our experience with pimozide indicates that this drug reduces the latter baseline stress level and therefore adds a valuable contribution to the treatment of such patients.
mesh_terms: D000328:Adult; D000342:Affective Symptoms / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010868:Pimozide / Q000009:adverse effects / Q000627:therapeutic use*; D011602:Psychophysiologic Disorders / Q000188:drug therapy; D013315:Stress, Psychological / Q000187:drug effects
chemical_list: D010868:Pimozide