Glycosylation of endogenous proteins through dolichol derivatives in reticulocyte plasma membranes.
It has been found that rabbit reticulocyte plasma membranes contain the enzymatic activities responsible for the synthesis of all the polyprenol-bound sugars that are intermediates in the glycosylation of proteins. The final reaction in which an oligosaccharide in transferred from a dolichol pyrophosphate derivative to an endogenous protein was detected in reticulocyte but not in erythrocyte plasma membranes.
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism*; D004224:Diterpenes / Q000378:metabolism*; D004288:Dolichol Phosphates / Q000378:metabolism; D004286:Dolichols / Q000378:metabolism*; D004910:Erythrocyte Membrane / Q000378:metabolism; D006023:Glycoproteins / Q000378:metabolism; D008970:Molecular Weight; D012156:Reticulocytes / Q000378:metabolism*; D014532:Uridine Diphosphate Glucose / Q000378:metabolism; D014537:Uridine Diphosphate N-Acetylglucosamine / Q000378:metabolism
D004224:Diterpenes; D004288:Dolichol Phosphates; D004286:Dolichols; D006023:Glycoproteins; D014537:Uridine Diphosphate N-Acetylglucosamine; D014532:Uridine Diphosphate Glucose