[Beta-glucuronidase activity in human ovarian tissue during the life- and cycle-phases of the woman].
The behaviour of the beta-glucuronidase activity during the life phases and the phase of the cycle of a woman has been studied in 51 human ovaries after the Dohrmann method. The study clearly indicates a dependency on age, that is demonstrated by a rise in beta-glucuronidase activity from 536 microgram Ph/h/g ovarial tissue during full functioning to 705 microgram Ph/h/g ovarial tissue in the premenopause and by dropping to 529 microgram Ph/h/g ovarial tissue in the menopause and the senium. The premenopause values are significantly higher compared to that of the other two functional phases. The activity of the beta-glucuronidase is significantly higher in the secretory phase than in the proliferation phase. Existing relations between the beta-glucuronidase of the ovary and the gonadotropic hormones of the hypophysis and the oestrogen metabolism are discussed.
D000328:Adult; D000367:Age Factors; D004967:Estrogens / Q000502:physiology; D005260:Female; D005966:Glucuronidase / Q000378:metabolism*; D006065:Gonadotropins, Pituitary / Q000378:metabolism; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D010053:Ovary / Q000201:enzymology*; D010902:Pituitary Gland / Q000502:physiology
D004967:Estrogens; D006065:Gonadotropins, Pituitary; D005966:Glucuronidase
Die beta-Glukuronidaseaktivität des menschlichen Ovarialgewebes während der Lebens- und Zyklusphasen der Frau.