title: The diagnostic accuracy and complications of closed lung biopsies.
abstract: The diagnostic yields and complication rates of closed lung biopsies were determined by responses to a questionnaire. Of 5,255 procedures reported, 30% were aspiration biopsies (AB), 7% tissue core biopsies (CB), 2% trephine biopsies (TR), 37% bronchial brush biopsies (BB), and 23% transbronchial biopsies (TB). Of these biopsies, 70% were done for suspected neoplasms. The diagnostic accuracy rates were: AB=82%, CB=84%, TR=86%, BB=61%, and TB=56%. Mortality rates were: AB=0.1%, CB=0.3%, TR=2.9%, BB=0.0%, and TB=0.3%. Transthoracic needle biopsies (AB, CB) had the highest overall diagnostic accuracy, with an associated low mortality and moderate morbidity.
mesh_terms: D001706:Biopsy / Q000009:adverse effects*; D001707:Biopsy, Needle / Q000009:adverse effects; D001999:Bronchoscopy; D003951:Diagnostic Errors; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D008168:Lung / Q000473:pathology*; D008171:Lung Diseases / Q000175:diagnosis / Q000473:pathology*