The effect of caffeine on uretheral motility.
An in vivo ureteral perfusion technique combined with a recently described methodology was used to study the effects of caffeine on ureteral motility patterns. Effects of the drug on the disused ureteric stump were also noted. The results showed a dose-related inhibition to complete cessation of peristalsis. Proposed mechanisms of caffeine effect on the ureter are discussed.
D000818:Animals; D002110:Caffeine / Q000494:pharmacology*; D004285:Dogs; D005260:Female; D008991:Monitoring, Physiologic; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects* / Q000502:physiology; D010477:Perfusion; D011312:Pressure; D014513:Ureter / Q000187:drug effects* / Q000502:physiology
D002110:Caffeine