The age distribution of human cancer for carcinogenic exposures of varying intensity.
The time and age dependence of cancer incidence rates resulting from various type of carcinogenic exposure are calculated and compared with observed cancer incidence rates. Implications for the detection of increased cancer incidence are discussed. The calculations assume that exposure affects one of several changes necessary for malignant cell transformation.
D000367:Age Factors; D002273:Carcinogens; D002471:Cell Transformation, Neoplastic; D004305:Dose-Response Relationship, Drug; D004781:Environmental Exposure; D006801:Humans; D008433:Mathematics; D009369:Neoplasms / Q000139:chemically induced*; D013997:Time Factors
D002273:Carcinogens