title: Studies on metatherian sex chromosomes. IV. X linkage of PGK-A with paternal X inactivation confirmed in erythrocytes of grey kangaroos by pedigree analysis.
abstract: Pedigree and population data are presented for erythrocyte phosphoglycerate kinase A (PGK-A) allozymes in the two species of grey kangaroo. The pedigree data confirm the hypothesis that PGK-A is X linked, the paternally derived X chromosomes being inactive in nucleated erythroblast precursors of the enucleate erythrocytes in females. The existence of different allozyme variants in eastern and western grey kangaroos further supports their division into separate species.
mesh_terms: D000818:Animals; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005787:Gene Frequency; D008040:Genetic Linkage; D006579:Heterozygote; D007527:Isoenzymes / Q000097:blood*; D007614:Macropodidae / Q000502:physiology*; D008297:Male; D008394:Marsupialia / Q000502:physiology*; D010375:Pedigree; D010735:Phosphoglycerate Kinase / Q000097:blood*; D012730:Sex Chromosomes; D013045:Species Specificity
chemical_list: D007527:Isoenzymes; D010735:Phosphoglycerate Kinase