Composition of O-alkyl and O-alk-1-enyl moieties in the glycerolipids of the human adrenal.
A comparison of human adult and fetal adrenals with respect to their levels of glyceryl ether lipids and other lipid components is reported. Fetal glands contained significantly lower levels of alk-1-enyl phosphoglycerides and of cholesterol. Neutral glyceryl ether diesters, and ethanolamine and choline phosphoglycerides were isolated from adult adrenal tissue. The composition of the O-alkyl glycerol groups in these lipid fractions was obtained by means of gas chromatography of the trimethylsilyl ethers and diacetyl derivatives; O-alk-1-enyl glycerols were analyzed as their diacetates. About one-half of the alkyl and alk-1-enyl glycerol moieties present in glyceryl ether diesters contained hydrocarbon side chains with 20, 22, or 24 carbon atoms. Long hydrocarbon chains (C19-24) were also found in the O-alkyl glycerol moieties present in the total lipids of fetal adrenals.
D000311:Adrenal Glands / Q000032:analysis* / Q000196:embryology; D000328:Adult; D002784:Cholesterol / Q000032:analysis; D005227:Fatty Acids / Q000032:analysis*; D005231:Fatty Acids, Unsaturated / Q000032:analysis; D005989:Glycerides / Q000302:isolation & purification; D005994:Glycerophosphates / Q000032:analysis; D006801:Humans; D008055:Lipids / Q000302:isolation & purification*; D010743:Phospholipids / Q000032:analysis
D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D005989:Glycerides; D005994:Glycerophosphates; D008055:Lipids; D010743:Phospholipids; D002784:Cholesterol