title: [Pathology and clinical aspects of retarded child development. Diagnosis and therapy of defective development].
abstract: 21 cases of "small for date" pregnancies were analysed. Serial ultrasonic tracings and determinations of total estrogen excretion in the 24-hour-urine and of serum HPL concentration were carried out. The fetal heart rate was measured by cardiotocogram. Retrospectively, the patients were divided into 3 groups according to birth weight. All patients were treated with a combination of Complamin, Calciparin and Partusisten. Fetal growth retardation could not be stopped by this treatment; there was, however, definite fetal weight gain following long term therapy. Results of HPL and total estrogen determinations were inconclusive; in most cases, however, a fall of concentrations was observed. Following long term therapy a rise in concentration up to almost normal values was seen. The positive effect of therapy was best shown by serial cardiotograms.
mesh_terms: D001623:Betamethasone / Q000627:therapeutic use; D001724:Birth Weight; D004359:Drug Therapy, Combination; D005260:Female; D005280:Fenoterol / Q000627:therapeutic use; D005317:Fetal Growth Retardation / Q000175:diagnosis / Q000628:therapy*; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D010927:Placental Insufficiency / Q000188:drug therapy; D011247:Pregnancy; D014465:Ultrasonics; D014590:Uterine Contraction / Q000187:drug effects; D014971:Xanthinol Niacinate / Q000627:therapeutic use
chemical_list: D005280:Fenoterol; D014971:Xanthinol Niacinate; D006493:Heparin; D001623:Betamethasone
vernacular_title: Pathologie und Klinik der retardierten Kindesentwicklung. Diagnose und Therapie der Mangelentwicklung.