title: [Toxicologic study of the antianemia preparation dextrafer].
abstract: Experiments were conduced with a twofold purpose, viz--to determine the medium lethal dose of the preparation and to study the dextrafer distribution in tissues of rabbits after its single or repeated intravenous infusion. The medium lethal dose of the drug was found to be 250 time greater than its maximal therapeutic dose. Morphological and histochemical observations showed dextrafer to have no toxic effect on the rabbits' tissues over a period of 2 years after its single intravenous infusion.
mesh_terms: D000208:Acute Disease; D000818:Animals; D002682:Chinchilla; D002908:Chronic Disease; D006397:Hematinics / Q000378:metabolism / Q000633:toxicity*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D011817:Rabbits; D013154:Spleen / Q000378:metabolism
chemical_list: D006397:Hematinics
vernacular_title: Toksikologicheskoe issledovanie antianemicheskogo preparata dekstrafera.