Prolonged succinylcholine-induced paralysis in connection with caesarean section. A case report.
A prolonged succinylcholine-induced paralysis was observed in connection with a casearean section in an otherwise healthy, 25-year-old female. Her serum pseudocholinesterase was analysed and found to be pathologically low, displaying in addition an atypical dibucaine number. Ten individuals related to her were also studied as regards pseudocholinesterase in serum. She had two brothers, one displaying the same pattern as herself, while the other had a normal pattern. Both of the parents had ordinary dibucaine numbers, while the father had a slightly decreased pseudocholinesterase activity. Possible mechanisms underlying the disorder are discussed.
D000328:Adult; D002091:Butyrylcholinesterase / Q000097:blood / Q000235:genetics; D002585:Cesarean Section; D003241:Consanguinity; D003992:Dibucaine / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D007744:Obstetric Labor Complications / Q000139:chemically induced*; D010243:Paralysis / Q000139:chemically induced*; D011247:Pregnancy; D013390:Succinylcholine / Q000009:adverse effects*; D013997:Time Factors
D002091:Butyrylcholinesterase; D013390:Succinylcholine; D003992:Dibucaine