The effect of aspirin pretreatment on the sweating response of older female subjects.
Seven healthy female volunteers (aged 50 to 67 years) have been subjected to a thermal stress and their sweat rates evaluated using hygrosensors on five different locations on their body surface. It was found that the sweating rate was highest on the forehead in all but one of the subjects with the chest being the next most prominent site for the response. Five of the subjects were restudied after aspirin pretreatment. In the presence of this drug, resting body temperature was lowered, sweating occurred at a lower oral temperature and the mean sweating rate at a standardized body temperature was significantly higher. These findings are consistent with aspirin's known pharmacological actions, although in this study the increased sweating rate have been demonstrated in afebrile subjects.
D000367:Age Factors; D000368:Aged; D001241:Aspirin / Q000494:pharmacology*; D001831:Body Temperature / Q000187:drug effects; D005260:Female; D006801:Humans; D008875:Middle Aged; D013268:Stimulation, Chemical; D013546:Sweating / Q000187:drug effects*
D001241:Aspirin