[Prednisone therapy in patients with pernicious anemia (report of 2 cases)].
The effects of Prednisone therapy at two patients with pernicious anemia were studied on haematologic response, gastric secretion and gastric mucosal hystology. The treatment resulted in each case in correctin of the megaloblastic to normoblastic erythropoesis, and increse in reticulocytes, hemoglobin level and red cell count. Schilling-s test was normalised in one case that means that Prednison enchanced B12 absorption. Gastric secretion of acid and gastric hystology were not respond during the Prednisone therapy. It was discused about immunological problems in pernicious anemia which are very important and required continued investigations.
D000752:Anemia, Pernicious / Q000188:drug therapy* / Q000276:immunology; D000917:Antibody Formation; D004357:Drug Synergism; D006801:Humans; D011241:Prednisone / Q000627:therapeutic use*; D012075:Remission, Spontaneous; D014805:Vitamin B 12 / Q000627:therapeutic use
D014805:Vitamin B 12; D011241:Prednisone
Osvt na primenu pronisona u bolesnika sa nelecenom pernicioznom anemijom (prikaz dva slucaja).