title: Slow evoked cortical responses to linear frequency ramps in subjects with cochlear lesions.
abstract: Slow evoked cortical potentials in response to linear frequency ramps of a continuous pure tone with a 1 kHz base frequency have been recorded from ten relatively young subjects with hearing loss of cochlear origin. At small frequency ramps, the N1-latency of their responses to the three ramp durations studied (20, 100, 500 msec) was significantly longer than those of a group with normal hearing. As the ramps are made larger, the difference between the latencies of the pathological group and the normal group becomes smaller; above a certain rate of frequency change, the latency of N1 becomes smaller in the pathological cases than in the normal group. This crossover occurs at frequency change rates around 1-3 kHz/sec. It is concluded that recording of evoked cortical responses to frequency ramps may provide an additional tool in the differential diagnosis of hearing disorders.
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D002540:Cerebral Cortex / Q000503:physiopathology*; D003051:Cochlea / Q000503:physiopathology*; D003638:Deafness / Q000503:physiopathology*; D005071:Evoked Potentials; D006801:Humans