[Antithromin activity following blockade of the reticuloendothelial system, splenectomy and partial removal of the liver].
The level of antithrombins II, III and IV decreased in proportion to the extent of intervention in destruction or removal of a part of the liver in rats. Destruction of the spleen led to depression, and removal--to activation of antithrombin IV. Back of the reticuloendothelial system caused a lesser fall of the antithrombin level than partial hepatectomy. The spleen is supposed to produce antithrombin IV inhibitor.
D000818:Animals; D000990:Antithrombin III / Q000096:biosynthesis; D000991:Antithrombins / Q000096:biosynthesis*; D006498:Hepatectomy; D008099:Liver / Q000378:metabolism*; D012157:Mononuclear Phagocyte System / Q000378:metabolism*; D051381:Rats; D013154:Spleen / Q000378:metabolism*; D013156:Splenectomy; D013997:Time Factors
D000991:Antithrombins; D000990:Antithrombin III
Antitrombinovaia aktivnost' pri blokade retikuloéndotelial'noĭ sistemy, splenektomii i chastichnom udalenii pecheni.