title: Pi (antitrypsin) typing methods. A comparison of acid starch-gel electrophoresis and isoelectric focusing.
abstract: The Pi typing methods acid starch-gel electrophoresis (ASGE) and isoelectric focusing (IEF) have been compared by three reference laboratories: 564 samples of phenotypes Pi M, MS and MZ were tested in each of the three laboratories with a 96% agreement on initial typing. The discrepancies are recorded and reasons for disagreement discussed. IEF is a reliable method for Pi typing and gives results comparable to those obtained by ASGE.
mesh_terms: D004592:Electrophoresis, Starch Gel; D006801:Humans; D007525:Isoelectric Focusing; D010641:Phenotype; D014361:Trypsin Inhibitors / Q000097:blood*
chemical_list: D014361:Trypsin Inhibitors