[Stress ulcer-an experimental study (author's transl)].
This experimental study demonstrates by means of electromagnetic flow measurements that hypovolaemic shock results in a significant decrease in gastric flow. 14 mongrel dogs were subjected to haemorrhagic shock for 3 or 4 hours. Significant histological changes are seen in the gastric mucosa as a result of the haemodynamic changes, especially when the duration of shock was 4 hours. All stages of stress ulcer from the superficial erosion to deep ulcers were documented. The possibility that the mast cell plays a pathogenetic role as mediator in the origination of a stress ulcer is considered.
D000818:Animals; D001794:Blood Pressure; D002445:Celiac Artery; D003594:Cytoplasmic Granules; D004285:Dogs; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D008297:Male; D008407:Mast Cells; D012769:Shock / Q000150:complications; D013270:Stomach / Q000098:blood supply; D013276:Stomach Ulcer / Q000209:etiology*; D013312:Stress, Physiological / Q000150:complications*; D014655:Vascular Resistance
Das Stressulkus-eine experimentelle Studie.