Carbohydrate content of endoscopic gastric biopsies in carcinoma of the stomach.
An investigation of the glycoproteins of gastric mucus from biopsies of patients with gastric cancer has shown a change in certain carbohydrate components. There is a significant increase (P less than 0-001) in mannose and a significant decrease in N-acetylgalactosamine in both secretors and non-secretors from cancer-free and cancer-bearing regions of the stomach as compared with normal stomachs. The possible reasons for this change and its relation to two possible glycoprotein fractions are discussed.
D000116:Acetylgalactosamine / Q000032:analysis*; D001706:Biopsy; D005688:Galactosamine / Q000031:analogs & derivatives*; D005753:Gastric Mucosa / Q000032:analysis*; D006023:Glycoproteins / Q000032:analysis; D006801:Humans; D008358:Mannose / Q000032:analysis*; D009093:Mucus / Q000032:analysis; D013274:Stomach Neoplasms / Q000032:analysis*
D006023:Glycoproteins; D005688:Galactosamine; D000116:Acetylgalactosamine; D008358:Mannose