title: Elevation of serum xanthine oxidase activity following halothane anesthesia in man.
abstract: Halothane, but not methoxyflurane, was found to cause specific hepatocellular damage, the hepatotoxicity being prompt but transient. The hepatotoxicity was demonstrated by the elevation in the serum activity of xanthine oxidase, a highly sensitive marker for acute liver damage.
mesh_terms: D000758:Anesthesia; D001219:Aspartate Aminotransferases / Q000097:blood; D006221:Halothane / Q000494:pharmacology*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008733:Methoxyflurane / Q000494:pharmacology; D013997:Time Factors; D014969:Xanthine Oxidase / Q000097:blood*
chemical_list: D008733:Methoxyflurane; D007770:L-Lactate Dehydrogenase; D014969:Xanthine Oxidase; D001219:Aspartate Aminotransferases; D006221:Halothane