Elimination of plasmids from several bacterial species by novobiocin.
Certain plasmids can be eliminated by exposure to growth-inhibiting concentrations of novobiocin. Novobiocin cured 8 of 14 plasmids (13 R-plasmids and an F' lac) among one or another of four different bacterial hosts.
D001419:Bacteria / Q000235:genetics*; D009675:Novobiocin / Q000494:pharmacology*; D010957:Plasmids / Q000187:drug effects*; D013045:Species Specificity
D009675:Novobiocin