Clinical evaluation of fenoterol aerosol in asthma.
Fenoterol and isoproterenol metered-dose inhalers were compared in 30 asthmatic patients by a double-blind, parallel-group study. FEV1 and FEF 25-75% values recorded after single doses on days 1, 45 and 90 of a three-month continuous treatment period showed that mean increases over baseline were significantly greater and lasted longer with fenoterol.
D000293:Adolescent; D000328:Adult; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy*; D001794:Blood Pressure / Q000187:drug effects; D004341:Drug Evaluation; D004983:Ethanolamines / Q000627:therapeutic use*; D005260:Female; D005280:Fenoterol / Q000009:adverse effects / Q000627:therapeutic use*; D005541:Forced Expiratory Volume; D006801:Humans; D007545:Isoproterenol / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008450:Maximal Midexpiratory Flow Rate; D008875:Middle Aged; D011674:Pulse / Q000187:drug effects
D000336:Aerosols; D004983:Ethanolamines; D005280:Fenoterol; D007545:Isoproterenol