title: [On the behaviour of carcinoma in situ of the cervix uteri (author's transl)].
abstract: The biological behaviour, the progression rate and the latency period of the carcinoma of the cervix uteri is discussed. We have tried to find out this by concluding indirectly and evaluating epidemiologically our own material, and considering the literature. Between 1967 and 1975 we bioptically diagnosed 1.933 in situ and 1.014 invasive cervial carcinomata. Among these there were 98 (9.7%) microcarcinomata. The average age of women with a carcinoma in situ in the years 1973-1975 was between 39 and 40 years. The average age of women with invasive carcinomata with the microcarcinoma excluded was 51-56 years. The average age of 98 women with a microcarcinoma during 1967--1975 was 47 years. The carcinoma in situ is a precursor of the invasive carcinoma in almost each case. The progression rate is approximately 30-50%. The latency period for the microcarcinoma is on a average of 7--10 years, till the clinical carcinoma 10--15 years. A reliable prognosis is impossible for the individual case.
mesh_terms: D000328:Adult; D000367:Age Factors; D002277:Carcinoma / Q000473:pathology; D002278:Carcinoma in Situ / Q000473:pathology*; D005260:Female; D005859:Germany, East; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000473:pathology*
vernacular_title: Zum biologischen Verhalten des Carcinoma in situ der Cervix uteri.