Synthesis of acylamino acid esters of nucleoside 5'-phosphates and their investigation with PMR and CD spectra.
The acylamino acid esters of nucleoside 5'-phosphates are synthesized via condensation of N-(N'-acylaminoacyl) imidazoles with nucleoside 5'-phosphates. The PMR and CD spectra of the esters obtained are studied. The 3'-isomers of the substances under study are observed to have a shift in the conformational N in equilibrium S equilibrium of the carbohydrate moiety in favour of the S-form as compared to the initial nucleosides and their 2'-acyl esters.
D000596:Amino Acids; D055598:Chemical Phenomena; D002621:Chemistry; D002942:Circular Dichroism; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009904:Optical Rotation; D012265:Ribonucleotides
D000596:Amino Acids; D012265:Ribonucleotides