[Animal-experiment studies on the effect of magnesium and vitamin B 6 on calcium-oxalate nephrolithiasis].
By chronic intoxication with ethylene glycol or acute intoxication by Na-glyoxalate in the animal experiment a Ca-oxalatenephrolithiasis could be produced. At this model the influence of magnesium, pyridoxine and phosphate was studied. The combination therapy of magnesium and vitamin B6 can completely prevent the formation of Ca-oxalate-microliths in the kidney. The production of a preparation with 200 mg MgO and 10 mg pyridoxine per tablet for the metaphylaxis of oxalate calculi is recommended.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D002614:Chelating Agents / Q000627:therapeutic use; D005260:Female; D007669:Kidney Calculi / Q000188:drug therapy* / Q000378:metabolism; D008274:Magnesium / Q000494:pharmacology / Q000627:therapeutic use*; D010070:Oxalates / Q000378:metabolism; D010085:Oxidative Phosphorylation / Q000187:drug effects; D011736:Pyridoxine / Q000494:pharmacology / Q000627:therapeutic use*; D011817:Rabbits
D002614:Chelating Agents; D010070:Oxalates; D008274:Magnesium; D011736:Pyridoxine; D002118:Calcium
Tierexperimentelle Untersuchungen über die Wirkung von Magnesium und Vitamin B6 auf die Kalziumoxalatnephrolithiasis.