title: alpha-Naphthylisothiocyanate (ANIT) hepatotoxicity and irreversible binding to rat liver microsomes.
mesh_terms: D015058:1-Naphthylisothiocyanate / Q000009:adverse effects* / Q000378:metabolism; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D004790:Enzyme Induction / Q000187:drug effects; D005978:Glutathione / Q000378:metabolism; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism*; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors; D011485:Protein Binding / Q000187:drug effects; D051381:Rats; D013861:Thiocyanates / Q000009:adverse effects* / Q000494:pharmacology
chemical_list: D013861:Thiocyanates; D015058:1-Naphthylisothiocyanate; D006899:Mixed Function Oxygenases; D005978:Glutathione