title: Congenital alacrima.
abstract: A sixteen-year-old black male with congenital alacrima and deficient salivary secretion demonstrated evidence of keratoconjunctivitis sicca. The workup revealed elevated immunoglobulins and histologically normal lacrimal and salivary glands, but there was deposition of amyloid in the conjunctival stroma. The differential diagnosis of the dry eye is discussed.
mesh_terms: D000293:Adolescent; D000682:Amyloid / Q000032:analysis; D003228:Conjunctiva / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000151:congenital* / Q000175:diagnosis / Q000503:physiopathology; D008297:Male; D012469:Salivary Glands / Q000378:metabolism / Q000503:physiopathology; D013666:Tears / Q000378:metabolism*
chemical_list: D000682:Amyloid