GC-MS measurement of deuterium in succinic anhydride and TMS-succinate. An isotope memory effect with succinic anhydride.
Direct GC-MS of succinic and glutaric anhydrides has been investigated, and shown to be feasible. In the GC-MS determination of deuterium in succinic anhydride, an isotope memory effect was observed, shown to be due to strong adsorption of solute onto the column. This phenomenon was investigated, together with possible methods for its suppression. Succinate TMS ester also was found to be a suitable derivative for direct GC-MS of deutero-succinic acid.
D000812:Anhydrides / Q000032:analysis; D002849:Chromatography, Gas; D003903:Deuterium / Q000032:analysis*; D013058:Mass Spectrometry; D013386:Succinates / Q000032:analysis*; D014297:Trimethylsilyl Compounds / Q000032:analysis
D000812:Anhydrides; D013386:Succinates; D014297:Trimethylsilyl Compounds; D003903:Deuterium