Role of tumor antigen in vaccine protection in Marek's disease.
Chickens vaccinated with HVT developed lymphoproliferative lesions and a cell-mediated immune response to MATSA. These observations are considered in view of the overall mechanism of vaccine protection in MD. A mechanism of vaccine action is proposed that suggests that MATSA immunity in vaccinated chickens may play an important role in protection.
D000818:Animals; D000951:Antigens, Neoplasm; D002471:Cell Transformation, Neoplastic; D002472:Cell Transformation, Viral; D002645:Chickens; D003602:Cytotoxicity, Immunologic; D006564:Herpesviridae / Q000276:immunology*; D007111:Immunity, Cellular; D008380:Marek Disease / Q000276:immunology* / Q000517:prevention & control; D014422:Turkeys; D014611:Vaccination; D014765:Viral Vaccines
D000951:Antigens, Neoplasm; D014765:Viral Vaccines