Hemoglobin Karatsu: beta 120 (GH 3) lysine leads to asparagine, an example of HB Riyadh in Japan.
Hemoglobin Karatsu was discovered in a Japanese male during a random survey of patients. Fingerprints of aminoethylated beta chain revealed an abnormal beta Tp12B-13 spot. Further chemical analyses and comparison with the corresponding tryptic peptide from Hb Hijiyama demonstrated an identical amino acid substitution with Hb Riyadh.
D000368:Aged; D000596:Amino Acids / Q000097:blood; D001216:Asparagine / Q000097:blood*; D004588:Electrophoresis, Cellulose Acetate; D006455:Hemoglobins, Abnormal / Q000302:isolation & purification*; D006801:Humans; D007564:Japan; D008239:Lysine / Q000097:blood*; D008297:Male; D010455:Peptides / Q000097:blood; D013057:Spectrum Analysis
D000596:Amino Acids; D006455:Hemoglobins, Abnormal; D010455:Peptides; D001216:Asparagine; D008239:Lysine