title: Vaccination of adult sheep with reduced doses of Brucella melitensis strain Rev.1: Safety and serological responses.
abstract: A trial was made to test the safety of a Brucella melitensis strain Rev. 1 vaccine when used in various doses on pregnant sheep and a control group of pregnant goats. It was found that local sheep were more susceptible than goats to the effects of this vaccine, and that the accepted dosage rate of 10+5 viable organisms, as recommended for adult goats, should not be used on pregnant sheep.
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D001428:Bacterial Vaccines / Q000008:administration & dosage; D002002:Brucella / Q000276:immunology*; D002006:Brucellosis / Q000276:immunology / Q000662:veterinary*; D005260:Female; D006041:Goats; D011247:Pregnancy; D012756:Sheep; D012757:Sheep Diseases / Q000276:immunology*; D012882:Skin Tests / Q000662:veterinary; D014611:Vaccination / Q000662:veterinary
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines