[Vectorgraphic assessment of the influence of different psychic stimulators on the avoidance behavior of rats].
The authors assessed the influence of psychostimulants on relearning of rats of the avoidance direction in a Y-maze. The effects were analyzed vectorographically with the absolute and relative values by the main response indices. The behaviour curve of the group of animals was drawn in both cases. Sydnocarb (20 mg/kg) produced the most optimal effect; in difference from caffeine (25 mg/kg) and d,1-amphetamine (0.5 mg/kg) it not only stimulated the active avoidance, but also improved the animal relearning. An increase of the sydnocarb dose to 50 mg/kg failed to disturb rat behaviour, whereas caffeine (50 mg/kg), and particularly d, 1-amphetamine (5 mg/kg) did cause such disturbance. The behaviour curve of the latter coursed beyond the level of the initial level and was characterized by a marked aggravation of passive avoidance.
D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001362:Avoidance Learning / Q000187:drug effects*; D002110:Caffeine / Q000494:pharmacology; D010069:Oxadiazoles / Q000494:pharmacology*; D051381:Rats; D013558:Sydnones / Q000494:pharmacology*
D000928:Antidepressive Agents; D010069:Oxadiazoles; D013558:Sydnones; D002110:Caffeine; D000661:Amphetamine
Vektorgraficheskaia otsenka vliianiia razlichnykh psikhostimuliatorov na izbegatel'noe povendenie krys.