title: An intravenous isotope method for measuring regional cerebral blood flow (rCBF) and volume (rCBV).
abstract: The regional cerebral blood flow (rCBF), intial slope index (ISI), transfer time (th) and volume (rCBV) were measured simultaneously in 43 hospital patients using a 133Xe intravenous injection method and quantitative dynamic 99Tcm brain scintigraphy. The measurements were made with a gamma camera and the data processing interfaced with a small digital computer. The following mean values and standard deviations were obtained from 50 control hemispheres standardized to the age of 40 years: (formular): see article. Good agreement was found between the blood flow values determined from the intra-arterial and intravenous injection techniques.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001810:Blood Volume; D001921:Brain / Q000000981:diagnostic imaging*; D001927:Brain Diseases / Q000000981:diagnostic imaging*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation; D005910:Glioma / Q000000981:diagnostic imaging; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000000981:diagnostic imaging; D008579:Meningioma / Q000000981:diagnostic imaging; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011877:Radionuclide Imaging; D012039:Regional Blood Flow; D013667:Technetium; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes; D013667:Technetium