title: [Inhibition of passive cutaneous anaphylaxis by dipeptides].
abstract: The action of some dipeptides (Lalpha-alanyl-histidine, Lbeta-alanyl-histidine, histidyl-leicine and glycyl-histidine), and histidine on passive cutaneous anaphylaxis of guinea pigs was studied. Lbeta-alanyl-histidine (karnosine) and Lalpha-alanyl-histidine proved to inhibit the passive cutaneous anaphylaxis. Histidyl-leicine, glycyl-histidine, and histidine failed to produce any inhibitory effect on passive cutaneous anaphylaxis.
mesh_terms: D000485:Allergens; D000818:Animals; D002336:Carnosine / Q000494:pharmacology; D003864:Depression, Chemical; D004151:Dipeptides / Q000494:pharmacology*; D006168:Guinea Pigs; D007073:Immunoglobulin E; D007074:Immunoglobulin G; D010323:Passive Cutaneous Anaphylaxis / Q000187:drug effects*; D011058:Pollen
chemical_list: D000485:Allergens; D004151:Dipeptides; D007074:Immunoglobulin G; D007073:Immunoglobulin E; D002336:Carnosine
vernacular_title: Tormozhenie passivnoĭ kozhnoĭ anafilaksii dipeptidami.