Time of origin and distribution of a new cell type in the rat cerebellar cortex.
A new cell type was identified in the granular layer of the rat cerebellum. It has a lightly staining nucleus with a nucleolus, it is spherical in shape and is larger than granule cells and smaller than Golgi cells. These pale cells are preferentially concentrated in the nodulus, the ventral uvula, the lingula, the flocculus, and parts of the paraflocculus. According to autoradiographic (3H-thymidine) evidence, over 60% of these pale cells are formed on embryonic days 19 and 20, and their production comes to an end soon after birth, prior to the differentiation of granule cells. The possible relation of pale cells to vestibular afferents of the cerebellar cortex is discussed.
D000818:Animals; D002525:Cerebellar Cortex / Q000166:cytology* / Q000196:embryology / Q000502:physiology; D005260:Female; D005865:Gestational Age; D008297:Male; D009474:Neurons / Q000166:cytology* / Q000502:physiology; D011247:Pregnancy; D051381:Rats