title: Macroamylasemia.
abstract: Macroamylasemia, characterized by hyperamylasemia and a normal urinary amylase, has no known specific clinical symptoms. The disparity in serum and urinary amylase levels is due to a macromolecular amylase complex too large for glomerular filtration. This syndrome is presented in a patient with cholecystitis and a partial small bowel obstruction accompanied by persistent pre- and postoperative hyperamylasemia with proven macroamylasemia. The renal amylase clearance to creatinine clearance (CAM/CCR) ratio confirms this hyperamylasemic entity.
mesh_terms: D000328:Adult; D000681:Amylases / Q000097:blood* / Q000378:metabolism / Q000652:urine; D003401:Creatine / Q000378:metabolism; D005260:Female; D006801:Humans; D007677:Kidney Function Tests; D008970:Molecular Weight
chemical_list: D000681:Amylases; D003401:Creatine