[Quantitative characteristics of the multiplication of muscle cells in the course of postnatal cardiogenesis in mice].
Changes in the absolute number of muscle cells and nuclei in the ventricle during the 1st year of postnatal life were followed in males of the CC57BR mice. The counts were carried out in the cell suspension obtained from the fixed cardiac muscle by means of alkaline dissociation. The number of muscle cells and nuclei reliably increased during the 1st month of life and ceased to increase when the maturity was attained (2-3 months). The number of muscle cells increased twice and that of muscle nuclei almost 4 times. A comparative estimate was made of the role of proliferation and growth of muscle cells in the increase of ventricle weight with the age. The importance of individual variation of the number of muscle cells and nuclei during early postnatal ontogenesis for the study of the myocardium adaptive growth is discussed.
D000818:Animals; D002452:Cell Count; D002467:Cell Nucleus; D006321:Heart / Q000254:growth & development*; D008297:Male; D051379:Mice / Q000254:growth & development*; D008815:Mice, Inbred Strains; D009206:Myocardium / Q000166:cytology*; D009929:Organ Size
Kolichestvennaia kharakteristika razmnozheniia myshechnykh kletok v techenie postnatal'nogo kardiogeneza u mysheĭ.