title: Effect of dietary ingestion of oxalic acid on growth and reproduction in male and female Long-Evans rats.
abstract: Male and female Long-Evans rats placed on a diet of Purina laboratory chow supplemented with 2.5 and 5.0% oxalic acid for a period of 70 days revealed decreased body weights and restricted growth rates. Ingestion of 5.0% oxalic acid depressed absolute organ weights of several visceral and endocrine tissues but enhanced the organ/body weight ratios of both male and female rats. Vaginal smears indicated disrupted estrous cycles.
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004032:Diet; D005260:Female; D006128:Growth / Q000187:drug effects*; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010070:Oxalates / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D012098:Reproduction / Q000187:drug effects*; D013997:Time Factors
chemical_list: D010070:Oxalates