The use of steroids in inhalation injury.
Steroids exert no beneficial effect upon acute pulmonary dysfunction created by nitrogen tetroxide inhalation and may worsen small airway obstruction in the early phases of injury. Treatment, therefore, is still largely symptomatic and supportive.
D000818:Animals; D002245:Carbon Dioxide / Q000097:blood; D004195:Disease Models, Animal; D006041:Goats; D008168:Lung / Q000187:drug effects / Q000473:pathology; D008170:Lung Compliance / Q000187:drug effects; D008171:Lung Diseases / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D008775:Methylprednisolone / Q000494:pharmacology / Q000627:therapeutic use*; D009589:Nitrogen Oxides / Q000009:adverse effects*; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure
D009589:Nitrogen Oxides; D002245:Carbon Dioxide; C015167:nitrogen tetroxide; D010100:Oxygen; D008775:Methylprednisolone