Relative electron capture response of the 2-chloroethyl derivatives of some barbituric acids and anticonvulsant drugs.
Data are given for the relative electron capture response of the 2-chloroethyl derivatives of ten barbituric acids and five common anticonvulsant drugs. Results indicate that these new derivatives significantly improve the detection limits of the barbituric acids but lead to no advantages for the anticonvulsant compounds. Structural features in the two classes of compounds are believed to explain the differences in the sensitivity of detection. Linear calibration plots exist for the concentration ranges 0.1-1.0 and 1.0-10.0 microgram/ml of amobarbital.
D000927:Anticonvulsants / Q000032:analysis*; D001463:Barbiturates / Q000032:analysis*; D002849:Chromatography, Gas / Q000379:methods; D006843:Hydrocarbons, Chlorinated / Q000032:analysis
D000927:Anticonvulsants; D001463:Barbiturates; D006843:Hydrocarbons, Chlorinated