[Effect of neuraminidase treatment of chick embryo fibroblasts on the adsorption and reproduction of the fowl plague virus].
Treatment with neuraminidase (100 units/ml) of chick embryo fibroblasts in vitro only partially inhibits adsorption of fowl plague virus on these cells. Cultivation of chick embryo fibroblasts in the presence of 50 units/ml neuraminidase had no effect on the sensitivity of these cells to fowl plague virus and on the extent of virus reproductions. It is suggested that neuraminic acid which is a component of the external cell membrane is not only substance responsible for adsorption of orthomyxoviruses.
D000327:Adsorption; D000818:Animals; D002642:Chick Embryo; D004305:Dose-Response Relationship, Drug; D005347:Fibroblasts / Q000187:drug effects; D009980:Influenza A virus / Q000187:drug effects*; D009439:Neuraminidase / Q000494:pharmacology*; D013997:Time Factors; D014776:Virus Cultivation; D014779:Virus Replication / Q000187:drug effects*
D009439:Neuraminidase
Vliianie obrabotki neĭraminidazoĭ fibroblastov kurinogo émbriona na adsorpbtsiiu i reproduktsiiu virusa chumy ptits.