Detection of benzoylecgonine in human urine.
A thin-layer chromatography (TLC) method is described that can be used to detect benzoylecgonine (BE), a metabolite of cocaine, in human urine. It is a two-part procedure that can be integrated into a rapid screening program for drug abuse. The first part of the method utilizes two TLC solvent systems to identify a variety of drugs, including BE. The second part is specific for the cocaine metabolite and can be used as a confirmation method. The procedure is sensitive to 3-4 microgram/ml of BE in urine.
D002855:Chromatography, Thin Layer / Q000379:methods; D003042:Cocaine / Q000031:analogs & derivatives* / Q000652:urine; D006801:Humans; D008403:Mass Screening; D008832:Microchemistry; D019966:Substance-Related Disorders
C005618:benzoylecgonine; D003042:Cocaine