title: Polyethylene glycol as a binder for tablets.
abstract: Polyethylene glycol 6000 was evaluated as a binder for the direct compression of 11 tablet formulations. Six formulations compressed quite well, and the resulting tablets were satisfactory in all respects. To evaluate stability, actual shelflife studies were considered more appropriate than the accelerated studies. After a shelflife of 3 years, five of the six formulations were stable. The ascorbic acid formulation was stable for up to 18 months.
mesh_terms: D002626:Chemistry, Pharmaceutical; D004355:Drug Stability; D005079:Excipients; D006244:Hardness; D014677:Pharmaceutical Vehicles; D011092:Polyethylene Glycols; D012995:Solubility; D013607:Tablets
chemical_list: D005079:Excipients; D014677:Pharmaceutical Vehicles; D013607:Tablets; D011092:Polyethylene Glycols