Serum cholinesterase: effect on the action of suxamethonium following administration to a patient with cholinesterase deficiency.
Purified serum cholinesterase 90 mg was administered to a patient with cholinesterase deficiency. The effect on the action of suxamethonium was studied. The half-life (44.7 h), time constant (64.5 h), rate constant (0.0155 h-1) and distribution volume (2740 ml) of the cholinesterase activity were determined.
D000368:Aged; D000768:Anesthesia, General; D002802:Cholinesterases / Q000097:blood / Q000172:deficiency* / Q000378:metabolism; D006207:Half-Life; D006801:Humans; D007700:Kinetics; D008297:Male; D013390:Succinylcholine / Q000494:pharmacology*
D002802:Cholinesterases; D013390:Succinylcholine