title: Virilization with diffuse involvement of ovarian androgen secreting cells.
abstract: A case is reported in which virilization of long duration and gradual progression was found in association with ovarian hyperthecosis and bilateral hilar cell lesions. The frequency occurrence of both masculinizing and nonmasculinizing ovarian tumors in association with ovarian hyperthecosis and polycystic ovaries is discussed.
mesh_terms: D000328:Adult; D000728:Androgens / Q000378:metabolism*; D005260:Female; D006801:Humans; D007984:Leydig Cell Tumor / Q000150:complications / Q000473:pathology; D010051:Ovarian Neoplasms / Q000150:complications / Q000473:pathology; D010053:Ovary / Q000473:pathology*; D011085:Polycystic Ovary Syndrome / Q000150:complications; D014770:Virilism / Q000150:complications / Q000473:pathology*
chemical_list: D000728:Androgens