title: The treatment of advanced carcinoma of the bladder with a combination of adriamycin and 5-fluorouracil.
abstract: 52 patients with advanced bladder cancer, no longer controlled by conventional therapy, have been treated by combination chemotherapy with Adriamycin and 5-fluorouracil. The objective remission rate has been 40%. The morbidity of the chemotherapy has not been excessive. The response has not been related to the histological grade of the primary tumour and previous treatment. Patients with a good performance status (Karnofsky index) have responded better than those with a poor performance status.
mesh_terms: D004317:Doxorubicin / Q000008:administration & dosage* / Q000627:therapeutic use; D004338:Drug Combinations; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D007275:Injections, Intravenous; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy*
chemical_list: D004338:Drug Combinations; D004317:Doxorubicin; D005472:Fluorouracil