title: Adrenalectomy, ovarian HCG-binding and the onset of female puberty in the rat.
abstract: The delay of puberty onset in female rats adrenalectomized before the 25th day of age is due neither to changes in the number of ovarian HCG-receptors nor to an altered hormone affinity of these receptors. It is assumed that glucocorticoids act on an intracellular level in the ovarian cells, possibly by alterations of cyclic AMP-dependent phosphodiesterase activity.
mesh_terms: D000311:Adrenal Glands / Q000502:physiology; D000315:Adrenalectomy; D000818:Animals; D001835:Body Weight; D006063:Chorionic Gonadotropin / Q000378:metabolism*; D005260:Female; D009929:Organ Size; D010053:Ovary / Q000378:metabolism*; D051381:Rats; D012741:Sexual Maturation; D013997:Time Factors
chemical_list: D006063:Chorionic Gonadotropin