Allergic laryngospasm on initiating oral propranolol therapy.
A 29-year-old woman suffered acute laryngospasm on taking the initial dose of propranolol hydrocholoride for the treatment of hypertension associated with a hyperdynamic circulatory state. Hypersensitivity to the tartrazine additive used as a stabilizing agent in oral propranolol appeared the likely cause of anaphylaxis, although a direct hypersensitivity to propranolol itself could not be excluded.
D000284:Administration, Oral; D000328:Adult; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D007826:Laryngismus / Q000139:chemically induced*; D011433:Propranolol / Q000008:administration & dosage / Q000009:adverse effects*
D011433:Propranolol