Ciclazindol and mazindol on glucose uptake into human isolated skeletal muscle: no interaction of mazindol with methysergide.
1 Ciclazindol, like mazindol, produced a significant concentration-dependent increase in glucose-uptake into human skeletal muscle in both the presence and absence of insulin. 2 Methysergide, which inhibits the action of fenfluramine on glucose-uptake into skeletal muscle, did not influence the effect of mazindol.
D004347:Drug Interactions; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007211:Indoles / Q000494:pharmacology*; D007328:Insulin / Q000494:pharmacology; D008454:Mazindol / Q000494:pharmacology*; D008784:Methysergide / Q000494:pharmacology*; D009132:Muscles / Q000187:drug effects / Q000378:metabolism*; D011743:Pyrimidines / Q000494:pharmacology
D007211:Indoles; D007328:Insulin; D011743:Pyrimidines; D008454:Mazindol; D005947:Glucose; D008784:Methysergide; C009990:ciclazindol