[Ultrastructure of cerebral cortex capillaries in stroke].
Analysing the data of electronomicroscopical studies on the dominant hemispheres of the cerebral cortex in 9 patients who died due to strokes, the authors consider the main types of pathological changes in the ultrastructure of capillaries that are of a diffuse generalizing character. They are the following: 1) dystrophy of the capillary wall with the accumulation in it of lysosomal inclusions, lipofuscin granules, with the disintegration of mitochondrias and disturbances of oxidation-reduction processes in the vessel tissues connected with it; 2) the growth and hyperplasia of the endothelium. These changes lead to dystrophic damages of neurons, the maintainance and loading of the course of the main pathological process. Hypoxia, as a result of local ischemia, has an important pathogenetical significance in the disturbances of brain circulation and leads to plasmorrhagia, brain edema and even greater affection of neurons.
D002196:Capillaries / Q000648:ultrastructure*; D002540:Cerebral Cortex / Q000098:blood supply*; D002561:Cerebrovascular Disorders / Q000473:pathology*; D004727:Endothelium; D006801:Humans; D008854:Microscopy, Electron
Ul'trastruktura kapilliarov kory mozga pri insul'te.