[The action of stabilised pilocarpine drops on the human eye (author's transl)].
The use of certain additional substances enables preparation of pilocarpin solutions which remainstable for at least 4 years, while the usual pilocarpin solutions were subject to a relatively early decomposition. A double-blind study with 30 patients demonstrates that there is no difference between the pharmacologic effect at the pure and the modified pilocarpin solution, which justifies the use of solutions with added substances to stablize the effective component.
D000328:Adult; D004355:Drug Stability; D005123:Eye / Q000187:drug effects*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D009883:Ophthalmic Solutions; D010862:Pilocarpine / Q000008:administration & dosage / Q000494:pharmacology*; D011680:Pupil / Q000187:drug effects; D013696:Temperature; D013997:Time Factors
D009883:Ophthalmic Solutions; D010862:Pilocarpine
Wirkung stabilisierter Pilocarpintropfen am menschlichen Auge.