[Molecular biology of aging. Part 9: Age-dependent effects of 2-mercapto-ethanol on protein synthesis in the cell-free system of the rat liver].
1. 2-Mercaptoethanol increases the incorporation of 14C-leucine in a microsomal system of rat liver. 2. This effect is causes by a direct influence on protein synthesis. 3. The microsomes of older animals are more stimulated and therefore the age differences are reduced.
D000375:Aging; D000818:Animals; D002474:Cell-Free System; D005260:Female; D007930:Leucine / Q000378:metabolism*; D008623:Mercaptoethanol / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000187:drug effects* / Q000378:metabolism; D014176:Protein Biosynthesis; D051381:Rats
D008623:Mercaptoethanol; D007930:Leucine
Zur Molekularbiologie des Alterns. 9. Mitteilung: Altersabhängige Wirkung von 2-Mercaptoäthanol auf die Protein-synthese im zellfreien System aus Rattenleber.