Increased permeability for plasma components of the cerebral vessels during acute angiotensin hypertension in rats.
Experimentally induced acute angiotensin hypertension has been shown to increase the permeability of cerebral arterioles, venules and veins to plasma components whthin a few hours. This increase in permiability was demonstrated by means of circulating homologous fluorescent serum proteins and colloidal carbon particles. The results support the view that an increased permeability of the cerebral vessels to plasma components is either a causal or an additional pathogenetic factor in the development of the hypertensive encephalopathy.
D000804:Angiotensin II; D000818:Animals; D001160:Arterioles / Q000378:metabolism; D001798:Blood Proteins / Q000378:metabolism; D001921:Brain / Q000098:blood supply*; D002199:Capillary Permeability; D002244:Carbon / Q000378:metabolism; D003102:Colloids; D005260:Female; D006973:Hypertension / Q000139:chemically induced / Q000503:physiopathology*; D051381:Rats; D014680:Veins / Q000378:metabolism; D014699:Venules / Q000378:metabolism
D001798:Blood Proteins; D003102:Colloids; D000804:Angiotensin II; D002244:Carbon