Failure of determination of fetal lung maturation due to false-negative lecithin/sphingomyelin ratio in a case of pierre robin syndrome.
A case is reported of a baby with Pierre Robin syndrome born at term with adequate lung maturity. The evaluation of fetal lung maturity before birth by means of the lecithin/sphingomyelin ratio and foam test in the amniotic fluid revealed immaturity of the lungs. Examination of the tracheal aspirate following delivery, however, showed adequate lung maturity in the neonate.
D000653:Amniotic Fluid / Q000032:analysis; D005188:False Negative Reactions; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis; D008168:Lung / Q000196:embryology; D010713:Phosphatidylcholines / Q000032:analysis*; D010855:Pierre Robin Syndrome / Q000175:diagnosis*; D012127:Respiratory Distress Syndrome, Newborn / Q000175:diagnosis*; D013109:Sphingomyelins / Q000032:analysis*
D010713:Phosphatidylcholines; D013109:Sphingomyelins