title: Eosinophilic granuloma and its variations.
abstract: The orthopedist is most likely to encounter solitary or multiple forms of eosinophilic granuloma of bone. Management includes curettage for diagnosis and treatment with insertion of autogenous bone. Radiation therapy and chemotherapy are reserved for patients with multiple lesions and for the less common forms of histiocytosis X, i.e., Hand-Schüller-Christian disease and Letterer-Siwe disease.
mesh_terms: D000293:Adolescent; D000328:Adult; D001847:Bone Diseases / Q000175:diagnosis; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004803:Eosinophilic Granuloma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis / Q000628:therapy; D006801:Humans