Endocrine aspects of trisomy 4p.
The main endocrinological parameters were investigated in two sisters affected with trisomy 4p. Our findings rule out any impairment of the endocrine system in this rare syndrome, even in those cases in which stunting of growth is more pronounced. The marked weight deficit in one of the two patients had no relationship to the chromosomal anomaly; it was determined by the association of a deficit of immunoglobulin with a Giardia Lamblia infestation.
D000293:Adolescent; D001786:Blood Glucose / Q000032:analysis; D002648:Child; D002905:Chromosomes, Human, 4-5; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D005873:Giardiasis / Q000276:immunology; D006130:Growth Disorders / Q000235:genetics; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007136:Immunoglobulins / Q000032:analysis; D007328:Insulin / Q000097:blood; D007422:Intestines / Q000473:pathology; D007986:Luteinizing Hormone / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D014314:Trisomy
D001786:Blood Glucose; D007136:Immunoglobulins; D007328:Insulin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D013006:Growth Hormone; D006854:Hydrocortisone