[Fall in serum complement prior to manifestation of hepatitis B in patients on chronic haemodialysis (author's transl)].
Haemolytic complement activity was measured in a long-term study in patients on haemodialysis. Four of the patients studied developed hepatitis B while under investigation. In all four patients a fall in haemolytic complement activity was observed one to three months before hepatitis B surface antigen was detected in the serum. The fall in complement activity also occurred prior to a rise in transaminase. The maximum fall averaged 27%.
D000328:Adult; D002908:Chronic Disease; D004796:Clinical Enzyme Tests; D003165:Complement System Proteins / Q000032:analysis*; D005260:Female; D006461:Hemolysis; D006509:Hepatitis B / Q000097:blood* / Q000201:enzymology; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009393:Nephritis / Q000628:therapy; D006435:Renal Dialysis; D013997:Time Factors
D006514:Hepatitis B Surface Antigens; D003165:Complement System Proteins
Serumkomplementabfall vor Hepatitis-B-Manifestation bei chronisch dialysierten Patienten.