Conceptual framework shifts in immunogenetics. I. A new look at cis AB antigens in the ABO system.
The so-called 'cis AB' blood group is accounted for by proposing that 'normal' anti-A and anti-B reagents are cross-reacting with partially overlapping reaction ranges. Hence, they are labelled anti-AX and anti-BX, respectively. Some consequences of a complex-simple model where 'cis AB' is accordingly produced by a simple (mono-factorial) antigen X (produced a simple gene X at the ABO-locus) are briefly explored.
D000017:ABO Blood-Group System; D000918:Antibody Specificity; D003429:Cross Reactions; D006801:Humans; D007125:Immunogenetics / Q000145:classification*; D010641:Phenotype
D000017:ABO Blood-Group System