title: [Antibiotics and the macroorganism (the causes and the mechanism of occurrence of side effects].
abstract: The main types of side reactions due to antibiotic therapy are described. The antibiotic groups most often being the cause of side reactions are presented. Dependence of the toxic (organotropic) effect of antibiotics on the therapy scheme, age and pathological changes in the mechanism of their excretion is indicated. The biochemical mechanisms of the side and selective effects of antibiotics are discussed.
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000494:pharmacology / Q000633:toxicity; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects; D001419:Bacteria / Q000187:drug effects; D002477:Cells / Q000187:drug effects; D004342:Drug Hypersensitivity / Q000145:classification; D006801:Humans; D007700:Kinetics; D008968:Molecular Conformation; D011506:Proteins / Q000037:antagonists & inhibitors; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D011506:Proteins
vernacular_title: Antibiotiki i makroorganizm (prichiny i mekhanizm vozniknoveniia pobochnykh reaktsiĭ).