Scanning electron microscopic studies on untreated and transformed mouse embryo fibroblast cell cultures.
Cultures of CBA T6T6 mouse embryo cells were transformed by 20-methylcholanthrene (MC) treatment in vitro. Untreated and MC treated cells and reexplanted cells of tumours originating from MC treated cells were compared by scanning electron microscopy (SEM). The 3 cultures showed considerable differences in the situation of the cells compared to each other, as well as in the number and shape of the surface formations.
D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D002478:Cells, Cultured; D005347:Fibroblasts / Q000187:drug effects*; D066298:In Vitro Techniques; D008748:Methylcholanthrene / Q000494:pharmacology*; D051379:Mice; D008808:Mice, Inbred CBA; D008855:Microscopy, Electron, Scanning
D008748:Methylcholanthrene