title: [Gonadotropic functions of the hypophysis in the induction and suppression of the development of testicular tumors in rats].
abstract: The work was carried out on 1379 mature rats. The content of gonadotropic hormones (TSH, LH, LBH) in the hypophysis was studied during the induction of specific testicular tumors. The development of germinogenic tumors (teratomas and serminomas) of testes was shown to proceed against the background of continuous enhancement of follicle-stimulating function of the hypophysis, while the occurrence of neoplasms from interstitial cells--against the background of persistently increased luteinizing function of the hypophysis. Suppression of FSH or LH production would prevent tumors development.
mesh_terms: D000728:Androgens; D000818:Animals; D002369:Castration; D003300:Copper; D004054:Diethylstilbestrol; D004967:Estrogens; D006062:Gonadotropins / Q000032:analysis / Q000378:metabolism*; D008297:Male; D010902:Pituitary Gland / Q000187:drug effects / Q000378:metabolism*; D011374:Progesterone; D011388:Prolactin / Q000032:analysis; D051381:Rats; D012636:Secretory Rate / Q000187:drug effects; D013431:Sulfates; D013736:Testicular Neoplasms / Q000378:metabolism*
chemical_list: D000728:Androgens; D004967:Estrogens; D006062:Gonadotropins; D013431:Sulfates; D011374:Progesterone; D004054:Diethylstilbestrol; D003300:Copper; D011388:Prolactin
vernacular_title: Gonadotropnye funktsii gipofiza pri induktsii i predotvrashchenii razvitiia opukholeĭ iaichka u krys.