Chronic interstitial pneumonitis with fibrosis after long-term therapy with nitrofurantoin.
Nitrofurantoin has been used widely as a urinary antiseptic. That it may cause pulmonary infiltration, and even fibrosis, has not been recognized universally. The literature contains 24 cases of interstitial pneumonitis with fibrosis. The results of treatment are summarized, and a new case is reported in detail.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002648:Child; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009582:Nitrofurantoin / Q000009:adverse effects* / Q000627:therapeutic use; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000473:pathology; D014552:Urinary Tract Infections / Q000188:drug therapy
D009582:Nitrofurantoin