Purification of 3-hydroxy-3-methylglutaryl coenzyme A reductase by affinity chromatography on blue dextran/Sepharose 4B. Comparison of enzyme purified from normal rats and from rats treated with cholestyramine.
D000429:Alcohol Oxidoreductases / Q000302:isolation & purification*; D000818:Animals; D002792:Cholestyramine Resin / Q000494:pharmacology*; D002846:Chromatography, Affinity; D003911:Dextrans; D004355:Drug Stability; D006358:Hot Temperature; D006903:Hydroxymethylglutaryl CoA Reductases / Q000302:isolation & purification* / Q000378:metabolism; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D008970:Molecular Weight; D051381:Rats; D012685:Sepharose
D003911:Dextrans; D002792:Cholestyramine Resin; D012685:Sepharose; D000429:Alcohol Oxidoreductases; D006903:Hydroxymethylglutaryl CoA Reductases