[The effect of pindolol on carbohydrate and fat metabolism in diabetes mellitus].
Twenty-seven diabetic patients, nine treated with insulin, nine treated with tolbutamid, and nine placed on diet, were given either pindolol or placebo 5 mg, three times daily during a 6-week period. The following 6-week period those receiving pindolol in the first 6 weeks received placebo and vice versa. Pindolol had no influence on the concentration of blood glucose, free fatty acids, triglycerides, or total cholesterol. The effect of pindolol on carbohydrate and fat metabolism appears to be of no clinical relevance in diabetic patients receiving their usual therapy.
D000328:Adult; D000368:Aged; D003920:Diabetes Mellitus / Q000178:diet therapy / Q000188:drug therapy / Q000378:metabolism*; D004040:Dietary Carbohydrates / Q000378:metabolism*; D004041:Dietary Fats / Q000378:metabolism*; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D008875:Middle Aged; D010869:Pindolol / Q000494:pharmacology*; D013997:Time Factors; D014044:Tolbutamide / Q000627:therapeutic use
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D007328:Insulin; D014044:Tolbutamide; D010869:Pindolol
Untersuchung zur Wirkung von Pindolol auf Kohlehydratund Fettstoffwechsel bei Diabetes mellitus.