Erythrocyte lipids in heterozygous carriers of duchenne muscular dystrophy.
Erythrocyte membranes from heterozygous carriers of Duchenne muscular dystrophy exhibit a diminished amount of palmitoleic acid when compared to membranes from normal subjects. A similar, but more variable, diminution is observed in the case of patients with this disorder. The change in fatty acid composition appears related to a low membrane triglyceride content and may provide both a possible technique for carrier detection and a clue regarding pathogenesis.
D004910:Erythrocyte Membrane / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism*; D005231:Fatty Acids, Unsaturated / Q000097:blood; D006579:Heterozygote; D006801:Humans; D008563:Membrane Lipids / Q000097:blood*; D009136:Muscular Dystrophies / Q000097:blood* / Q000235:genetics; D014280:Triglycerides / Q000097:blood
D005231:Fatty Acids, Unsaturated; D008563:Membrane Lipids; D014280:Triglycerides