Incidence of fracture in epileptics.
In 87 epileptics on diphenylhydantoin, the occurrence of non-seizure-related fractures, over a period of 7 years, was six times greater than that found in the normal population. The significant increase in fracture incidence was found to lie within the 45-64 age group indicating that eipleptics are not only more prone to fractures but also have an earlier fracture début.
D000328:Adult; D000367:Age Factors; D000368:Aged; D004827:Epilepsy / Q000150:complications* / Q000188:drug therapy; D005260:Female; D050723:Fractures, Bone / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010018:Osteomalacia / Q000150:complications; D010672:Phenytoin / Q000627:therapeutic use; D012737:Sex Factors; D013548:Sweden
D010672:Phenytoin