[Validation of the subcutaneous-jet method of smallpox vaccination].
Reactogenic properties and survival of the smallpox vaccine virus in the organism of the vaccinated rabbits were studied for the purpose of experimental substantiation of the subcutaneous-jet method of smallpox vaccination; serological shifts were determined, and also the intensity of the immunity created to the intracerebral and intranasal infection with the pathogenic strain of the causative agent was assessed. The results of experiment were confirmed in revaccination of humans pointing to weak reactogenic properties and high immunological efficacy of the subcutaneous-jet method of smallpox vaccination.
D000818:Animals; D007271:Injections, Intradermal; D007277:Injections, Jet; D007279:Injections, Subcutaneous; D011817:Rabbits; D012899:Smallpox / Q000517:prevention & control*; D012900:Smallpox Vaccine / Q000008:administration & dosage*; D014611:Vaccination
D012900:Smallpox Vaccine
Obosnovanie podkozhno-bezygol'nogo metoda ospoprivivaniia.