title: Refinement of the fluid-mosaic model of membrane structure.
abstract: Certain molecular packing criteria previously employed in a quantitative analysis of lipid micelles and bilayers are here extended to biological membranes. The inclusion of both thermodynamic and packing considerations point to a highly complex self-assembly mechanism in which the organization of lipids and proteins is highly coupled, with far reaching consequences as regards the structure and function of biological membranes.
mesh_terms: D008563:Membrane Lipids; D008565:Membrane Proteins; D008566:Membranes; D008961:Models, Structural; D013816:Thermodynamics
chemical_list: D008563:Membrane Lipids; D008565:Membrane Proteins