Obstructive jaundice due to a chlorinated hydrocarbon in breast milk.
A 6-week-old breast-fed infant had obstructive jaundice and hepatomegaly. When a dry-cleaning solvent, tetrachloroethylene, was detected in the mother's milk and blood, breast-feeding was discontinued. Rapid clinical and biochemical improvement followed. The child grew normally and had normal liver function during 2 years of follow-up.
D000395:Air Pollutants, Occupational; D001942:Breast Feeding; D002779:Cholestasis / Q000139:chemically induced*; D005260:Female; D006529:Hepatomegaly / Q000139:chemically induced; D006801:Humans; D007223:Infant; D008895:Milk, Human / Q000032:analysis*; D013750:Tetrachloroethylene / Q000032:analysis / Q000506:poisoning*
D000395:Air Pollutants, Occupational; D013750:Tetrachloroethylene