Regulation of de novo purine synthesis in human lymphoblasts. Similar rates of de novo synthesis during growth by normal cells and mutants deficient in hypoxanthine-guanine phosphoribosyltransferase activity.
D002455:Cell Division; D002460:Cell Line; D006801:Humans; D007041:Hypoxanthine Phosphoribosyltransferase / Q000172:deficiency / Q000378:metabolism*; D007042:Hypoxanthines / Q000494:pharmacology; D007700:Kinetics; D008214:Lymphocytes / Q000378:metabolism; D009154:Mutation; D010754:Phosphoribosyl Pyrophosphate / Q000378:metabolism; D011687:Purines / Q000096:biosynthesis*
D007042:Hypoxanthines; D011687:Purines; D010754:Phosphoribosyl Pyrophosphate; D007041:Hypoxanthine Phosphoribosyltransferase