Role of lower esophageal sphincter incompetence in recurrent pneumonia after repair of esophageal atresia.
The etiology of recurrent aspiration pneumonitis after the successful repair of esophageal atresia has not been defined. In order to explain this occurrence, we performed esophageal manometric examinations on eight patients who had undergone repair of EA and tracheoesophageal fistula. Two patients who had had recurrent pneumonia had subnormal pressure of the lower esophageal sphincter; they also had a history of severe regurgitation, and a barium esophagram demonstrated free gastroesophageal reflux. The LES incompetence in these patients was apparently corrected by administration of bethanechol.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004933:Esophageal Atresia / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D004943:Esophagogastric Junction / Q000503:physiopathology*; D006801:Humans; D007223:Infant; D008365:Manometry; D011014:Pneumonia / Q000209:etiology* / Q000503:physiopathology; D011183:Postoperative Complications; D012008:Recurrence; D014138:Tracheoesophageal Fistula / Q000150:complications / Q000503:physiopathology / Q000601:surgery