title: Increasing frequency of thyroid goiters in Coho salmon (Oncorhynchus kisutch) in the Great Lakes.
abstract: Coho salmon collected during the 1976 spawning runs from Lakes Michigan, Ontario, and Erie had overt goiter frequencies of 6.3, 47.6, and 79.5%, respectively. These represent significant increases over the frequencies observed in previous years. Epizootiological data suggest that environmental goitrogens (possibly pollutants) may be involved in the etiology of the thyroid disorder.
mesh_terms: D000818:Animals; D005393:Fish Diseases / Q000209:etiology*; D006042:Goiter / Q000097:blood / Q000209:etiology / Q000662:veterinary*; D006114:Great Lakes Region; D007455:Iodine / Q000172:deficiency; D012474:Salmon; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood; D014873:Water Pollutants / Q000009:adverse effects*; D014874:Water Pollutants, Chemical / Q000009:adverse effects*
chemical_list: D014873:Water Pollutants; D014874:Water Pollutants, Chemical; D014284:Triiodothyronine; D007455:Iodine; D013974:Thyroxine