Orientation of cell-surface antigens in the lipid bilayer of lymphocyte plasma membrane.
Human HLA-A, B, C and Ia antigens were labelled by lactoperoxidase-catalysed iodination of the inner surface of lymphocyte plasma membrane and thus are transmembrane proteins. In contrast, membrane-bound human IgM and mouse IgM, IgD and Thy-1 antigen were not labelled on the inner membrane surface.
D000818:Animals; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology / Q000648:ultrastructure; D006680:HLA Antigens; D006801:Humans; D007072:Immunoglobulin D; D007075:Immunoglobulin M; D007455:Iodine; D007519:Isoantigens; D007784:Lactoperoxidase / Q000378:metabolism; D008214:Lymphocytes / Q000276:immunology* / Q000648:ultrastructure; D008565:Membrane Proteins / Q000276:immunology*; D051379:Mice; D011947:Receptors, Antigen, B-Cell; D013154:Spleen / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology
D006680:HLA Antigens; D007072:Immunoglobulin D; D007075:Immunoglobulin M; D007519:Isoantigens; D008565:Membrane Proteins; D011947:Receptors, Antigen, B-Cell; D007455:Iodine; D007784:Lactoperoxidase