Changes in cardiac output distribution after liver dearterialization in the rat.
The changes in cardiac output distribution in rats have been studied after hepatic artery ligation and additional ligament division. These procedures resulted initially in a marked decrease in the arterial blood supply to the liver and this effect was pronounced still four weeks after the operation. Evidence was found that the decrease in liver blood supply induced by the procedure was in part counterbalanced by arteriovenous shunting in the preportal region. Furthermore, a temporary redistribution of cardiac output with reduced fractions to colon and spleen was found two weeks after these operations.
D000818:Animals; D002302:Cardiac Output; D006499:Hepatic Artery / Q000601:surgery*; D008026:Ligation; D008099:Liver / Q000098:blood supply*; D008297:Male; D008863:Microspheres; D051381:Rats; D013997:Time Factors