DNA injection and genetic recombination of alkylated bacteriophage T7 in the presence of nalidixic acid.
Marker rescue experiments with alkylated T7 bacteriophage carried out in the presence and in the absence of nalidixic acid suggest that the gradient in rescue is due to two alkylation-induced causes: a DNA injection defect and an interference with DNA synthesis.
D003090:Coliphages / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D004279:DNA, Viral / Q000096:biosynthesis / Q000235:genetics*; D005814:Genes, Viral; D009268:Nalidixic Acid / Q000494:pharmacology*; D011995:Recombination, Genetic / Q000187:drug effects*
D004279:DNA, Viral; D009268:Nalidixic Acid