title: [Oral kallikrein-therapy of asthenozoospermia].
abstract: Over a period of 7 weeks 51 men with idiopathic asthenozoospermia were treated with Kallikrein (600 Kallikrein units per day). A statistically significant improvement of sperm motility was observed with a maximum 1 month after the therapy. The conception rate was 31%. Stimulation of sperm motility may be caused by a positive effect on spermatogenesis, by an improvement of the nutritional functions of the tubulus apparatus and by an improvement of sperm maturation in the eqididymis.
mesh_terms: D000284:Administration, Oral; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy*; D007610:Kallikreins / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D013081:Sperm Motility / Q000187:drug effects; D013091:Spermatogenesis / Q000187:drug effects; D013997:Time Factors
chemical_list: D007610:Kallikreins
vernacular_title: Orale Kallikrein-Therapie der Asthenozoospermie.