Studies on immunity to mouse sarcomas using the tumor-cell neutralization test.
Statistical analysis of the results of tumor-cell neutralization (Winn) tests has been presented in a refined manner using three variables: tumor incidence, time to palpable tumor, and growth rate. The concept of relative risk and the Z statistic were used to describe the latter two variables. This analysis is then applied to a particular experiment. Lymphocytes sensitized in vitro were compared with specifically immune lymphocytes and were found to facilitate the growth rate. Further applications of this analysis are discussed.
D000042:Absorption; D000818:Animals; D000941:Antigens; D007111:Immunity, Cellular; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D009500:Neutralization Tests / Q000379:methods*; D012306:Risk; D012513:Sarcoma, Experimental / Q000276:immunology*; D013223:Statistics as Topic; D013997:Time Factors
D000941:Antigens