title: [Possible pharmacologic regulation of the motor activity of the gastrointestinal tract].
abstract: The authors present the results of pharmacological study of the effects of gallic salt cynoglossofin-geliosupin alkaloid (cyngal), isolated from the Cynoglossum officinale, on the gastrointestinal motor activity. A high stimulating activity of this preparation both in acute and chronic experiments on dogs was shown by using the balloon and electrographic recording technique. The ability of cyngal to release serotonin from the bound state can account for the gastrointestinal motor function stimulation.
mesh_terms: D000470:Alkaloids / Q000494:pharmacology*; D000818:Animals; D001659:Biliary Tract / Q000187:drug effects; D002415:Cats; D004064:Digestive System / Q000187:drug effects / Q000378:metabolism; D004285:Dogs; D004594:Electrophysiology; D005769:Gastrointestinal Motility / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects; D010277:Parasympathomimetics; D010946:Plants, Medicinal / Q000032:analysis*; D051381:Rats; D012701:Serotonin / Q000378:metabolism; D013268:Stimulation, Chemical
chemical_list: D000470:Alkaloids; D010277:Parasympathomimetics; D012701:Serotonin
vernacular_title: O vozmozhnostiakh farmakologicheskoĭ reguliatsii motornoĭ deiatel'nosti pishchevaritel'nogo apparata.