An analytical approach to the quantitation of known drugs in human biological samples by HPLC.
Although many HPLC methods are available in the literature only a fraction of these are applicable to the analysis of known drugs in human biological fluids. This paper presents the favoured approach of a laboratory involved in the quantitative assay of drugs in man for the subsequent study of pharmacokinetics and bioavailability.
D000493:Allopurinol / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D004077:Digoxin / Q000032:analysis; D006801:Humans; D008722:Methods; D010117:Oxypurinol / Q000032:analysis; D004364:Pharmaceutical Preparations / Q000032:analysis*; D013420:Sulfamethoxazole / Q000032:analysis; D014295:Trimethoprim / Q000032:analysis
D004364:Pharmaceutical Preparations; D000493:Allopurinol; D004077:Digoxin; D014295:Trimethoprim; D010117:Oxypurinol; D013420:Sulfamethoxazole