Experimental bypass of the left ventricle.
Bypass of the left ventricle was accomplished in dogs and the entire circulation was supported temporarily by only the right ventricle. The atrial septum was excised, and the atrium was repartitioned so that the pulmonary veins were in continuity with the right ventricle and the venae cavae were connected through the atrium. Anastomosis of the superior vena cava to the right pulmonary artery brought systemic venous return directly to the lungs. The main pulmonary artery was ligated proximal to the bifurcation, preserving distal confluence of right and left pulmonary arteries. A tubular prosthesis between the proximal pulmonary artery and the aorta connected the right ventricle to the systemic circuit. This procedure, or some modification of the principle, may have clinical feasibility in the treatment of patients with hypoplastic left heart syndrome.
D000818:Animals; D001011:Aorta / Q000002:abnormalities / Q000601:surgery*; D001775:Blood Circulation; D001807:Blood Vessel Prosthesis; D003326:Coronary Circulation; D004195:Disease Models, Animal; D004285:Dogs; D006346:Heart Septum / Q000601:surgery; D006352:Heart Ventricles / Q000002:abnormalities / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D011312:Pressure; D011651:Pulmonary Artery / Q000601:surgery*; D013577:Syndrome; D014683:Vena Cava, Superior / Q000601:surgery*