The procoagulant activity of adipose tissue.
Homogenates of several rat and human adipose tissues contain procoagulant activity mainly due to the presence of tissue thromboplastin. Intravenous injections in rats of the active fraction from such homogenates cause the accumulation of 51Cr-labelled platelets and 125I-labelled fibrin  in the lungs. The effect of phospholipase C and of specific antibodies against tissue thromboplastin on this procoagulant activity of adipose tissue has been studied in vitro and in vivo.
D000273:Adipose Tissue / Q000032:analysis; D000818:Animals; D000906:Antibodies; D001059:Apoproteins / Q000276:immunology; D001777:Blood Coagulation; D006801:Humans; D008297:Male; D010740:Phospholipases / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013925:Thromboplastin / Q000032:analysis; D013997:Time Factors
D000906:Antibodies; D001059:Apoproteins; D013925:Thromboplastin; D010740:Phospholipases