[Effect of lithium salts on the ultrastructure of isolated cerebral mitochondria exposed to the serum of schizophrenic patients].
The author studied the influence of lithium chlorous on the ultrastructure of isolated brain hemispheric mitochondria of cats, subjected to the action of the blood sera of schizophrenic patients and normal donors. The data demonstrated similar changes in the mitochondria structures under the action of schizophrenic patients and normals. Lithium to a certain extent prevents disorders in the mitochondria structure which appear in an incubation with the blood serum. This effect of lithium is expressed in the same way in the presence of the blood serum of schizophrenic patients and normal donors and is considered to be nonspecific.
D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000187:drug effects / Q000648:ultrastructure*; D006801:Humans; D007106:Immune Sera / Q000494:pharmacology*; D008094:Lithium / Q000494:pharmacology*; D008854:Microscopy, Electron; D008928:Mitochondria / Q000187:drug effects*; D012559:Schizophrenia / Q000097:blood*
D007106:Immune Sera; D008094:Lithium
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