Cutaneous infection by Cryptococcus laurentii.
Cryptococcus laurentii was isolated twice from cutaneous granulomas in the leg and foot of a 40-year-old man. Histologically the cells of C. laurentii were found in groups in the dermis and also inside giant cells. There was epithelioid cell infiltration in the dermis and subcutis. An atypical mycobacterium was isolated in addition to C. laurentii. Therapy with anti-tuberculous drugs after an initial amphotericin B infusion was found to be satisfactory.
D000328:Adult; D003453:Cryptococcosis / Q000473:pathology; D005533:Foot Dermatoses / Q000473:pathology*; D006099:Granuloma / Q000209:etiology / Q000473:pathology; D006801:Humans; D007868:Leg Dermatoses / Q000473:pathology*; D008297:Male; D012876:Skin Diseases, Parasitic / Q000473:pathology*