Uptake and distribution of cadmium in mice following repeated administrations.
The research was undertaken to analyze the uptake and distribution of cadmium-109 in mice following repeated injections and to observe how the simultaneous administrations of zinc affected the cadmium retention. Mice were given one, two, or three intravenous administrations at 48-hr intervals. Animals were sacrificed 2 min to 48 hr after each injection. Zinc had little effect on the retention of cadmium in the samples analyzed, and injections behaved independently of each other.
D000818:Animals; D002104:Cadmium / Q000008:administration & dosage / Q000378:metabolism* / Q000494:pharmacology; D004347:Drug Interactions; D006168:Guinea Pigs; D007275:Injections, Intravenous; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009928:Organ Specificity; D011868:Radioisotopes; D013997:Time Factors; D014018:Tissue Distribution; D015032:Zinc / Q000494:pharmacology
D011868:Radioisotopes; D002104:Cadmium; D015032:Zinc