title: [Proteins of rat brain synaptic structures during conditioned reflex activity].
abstract: A comparative study was made of the structural-functional groups of proteins of synaptic structures in the cerebral cortex of albino rats during elaboration of a simple food-procuring reflex in one session. The results of estimation of quantitative and qualitative protein changes by the methods of isotope analysis and discelectrophoresis on polyacrylamide gel point to dissimilar changes in membrane and synapto-plasmatic proteins during learning. The process of temporary connections formation is accompanied by structural-chemical reorganizations of the synaptic membranes which evidently involve conformative transitions of external and integral proteins. There is a drastic rise in the rate of metabolism in the group of watersoluble proteins during learning, along with a possibility of "local" changes of synthesis in the fraction of low-molecular proteins.
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000032:analysis / Q000502:physiology* / Q000648:ultrastructure; D055598:Chemical Phenomena; D002621:Chemistry; D003214:Conditioning, Classical / Q000502:physiology*; D003593:Cytoplasm / Q000502:physiology; D004589:Electrophoresis, Disc; D008297:Male; D008565:Membrane Proteins / Q000502:physiology; D008970:Molecular Weight; D009419:Nerve Tissue Proteins / Q000032:analysis / Q000502:physiology*; D011092:Polyethylene Glycols; D051381:Rats; D012967:Sodium Dodecyl Sulfate; D012995:Solubility; D013570:Synaptic Membranes / Q000502:physiology; D013574:Synaptosomes / Q000032:analysis
chemical_list: D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; D012967:Sodium Dodecyl Sulfate; D011092:Polyethylene Glycols
vernacular_title: Issledovanie belkov sinapticheskikh struktur golovnogo mozga krys pri uslovnoreflektronoĭ deiatel'nosti.