title: Cascarosides A and B.
abstract: Electron-impact and field desorption mass spectrometry, together with NMR and circular dichroism spectroscopy, were used to confirm that cascarosides A and B are C-10 isomers of 8-O-(beta-D-glucopyranosyl)barbaloin. Several batches of cascarosides A and B were prepared and oxidatively hydrolyzed to aloe-emodin. The results are discussed in relation to the assay for cascara given in the European Pharmacopoeia, 1971.
mesh_terms: D000880:Anthraquinones / Q000032:analysis* / Q000302:isolation & purification; D055598:Chemical Phenomena; D002621:Chemistry; D004642:Emodin / Q000032:analysis; D005960:Glucosides / Q000032:analysis / Q000302:isolation & purification; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010084:Oxidation-Reduction; D010944:Plants / Q000032:analysis
chemical_list: D000880:Anthraquinones; D005960:Glucosides; C518327:aloe emodin; D004642:Emodin