Macrodactyly in the foot.
Seven patients with macrodactyly in the foot are reported. None showed any stigmata of neurofibromatosis and all were found to have excessive accumulation of fibro-fatty tissue as the most striking pathological feature. It is suggested that this may represent the basic lesion in this condition. The literature is reviewed and attention is drawn to the differences between macrodactyly in the hand and in the foot.
D000273:Adipose Tissue / Q000473:pathology; D000671:Amputation, Surgical; D001848:Bone Diseases, Developmental / Q000473:pathology / Q000601:surgery*; D005260:Female; D005528:Foot / Q000601:surgery*; D005531:Foot Deformities, Acquired / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011859:Radiography; D014034:Toes / Q000000981:diagnostic imaging / Q000601:surgery