No evidence for linkage disequilibrium between Bf and GLO in African negroids.
A sample of South African Negroids (n = 791) was scored for each individual's Bf and GLO phenotype. (The genes for the Bf and GLO olymorphisms are included in a known cluster of linked genes on chromosome 6.) Following a x2-test the respective two series of alleles were found to be disturbed at random, i.e., there was no evidence for a linkage disequilibrium. This result is discussed in terms of the linkage relationships and map distances of the genetic markers involved.
D000483:Alleles; D044383:Black People; D002906:Chromosomes, Human, 6-12 and X; D011415:Complement Factor B / Q000235:genetics*; D004792:Enzyme Precursors / Q000235:genetics*; D008040:Genetic Linkage; D006801:Humans; D007791:Lactoylglutathione Lyase / Q000235:genetics*; D008190:Lyases / Q000235:genetics*; D008433:Mathematics; D010641:Phenotype; D011110:Polymorphism, Genetic; D013019:South Africa
D004792:Enzyme Precursors; D011415:Complement Factor B; D008190:Lyases; D007791:Lactoylglutathione Lyase