Congenital solitary fibromatosis of soft tissues, a variant of congenital generalized fibromatosis. 2 cases reports.
A report of 2 cases of solitary fibromatosis in a 10-day-old boy and a girl 3 years and 10 months old is presented. Both lesions were deep-seated and showed a nodular and infiltrating growth, predominantly buil-up by immature fibroblast-like cells and including hemangiopericytoma-like areas. One of the lesions also showed leiomyoma-like areas. An ultrastructural study however, revealed no intra-cytoplasmatic myofilaments. At follow-up examinations after 21 years and 1 year, respectively, there were no signs of recurrences or metastases. These 2 cases are considered to represent a solitary form of congenital generalized fibromatosis. The differential diagnosis from infantile hemangiopericytoma and fibrous lesions seen in infancy and early childhood, such as infantile fibrosarcoma, diffuse infantile fibromatosis, extra-abdominal desmoid, fibrous hamartoma of infancy and juvenile aponeurotic fibroma, is discussed.
D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005350:Fibroma / Q000151:congenital* / Q000473:pathology / Q000648:ultrastructure; D005500:Follow-Up Studies; D006393:Hemangiopericytoma / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012983:Soft Tissue Neoplasms / Q000151:congenital* / Q000473:pathology / Q000648:ultrastructure