[ABO compatibility and isoimmune neonatal thrombopenia].
25 families with serologically documented isoimmune neonatal thrombopenia were investigated for ABO-antigens of mother and child. In all cases mother and child were ABO-compatible. It is concluded that feto-maternal ABO-compatibility is a prerequisite for the development of isoimmune neonatal thrombopenia; hence, platelets must have ABO-antigens or be covered by soluble ABO-antigens.
D000017:ABO Blood-Group System; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000276:immunology*; D007518:Isoantibodies; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D013921:Thrombocytopenia / Q000276:immunology*
D000017:ABO Blood-Group System; D007518:Isoantibodies
ABO-Kompatibilität und isoimmune neonatale Thrombopenie.