Detection of penicillin G and ampicillin as contaminants in tetracyclines and penicillamine.
A method was developed to detect residual levels of ampicillin and penicillin G in various tetracyclines and penicillamine. Residues are detected by reversed-phase TLC followed by bioautography. The directness of the techniques makes this method a good means of detecting residual contaminants in drugs.
D000667:Ampicillin / Q000032:analysis*; D001681:Biological Assay / Q000379:methods; D002855:Chromatography, Thin Layer; D004340:Drug Contamination; D008722:Methods; D010396:Penicillamine / Q000032:analysis*; D010400:Penicillin G / Q000032:analysis*; D012505:Sarcina / Q000187:drug effects; D013754:Tetracyclines / Q000032:analysis*
D013754:Tetracyclines; D000667:Ampicillin; D010396:Penicillamine; D010400:Penicillin G