The effect of glypondin on glycogen and protein accumulation in rat organs.
Rats were treated for 21 days with 20, 30 and 40 mg/kg Glypondin dissolved in the drinking water. The weight-increasing effect of Glypondin was studied in rat organs. In the liver a significant rise in the concentration of TCA-soluble glycogen was demonstrated. In the myocardium and m. gastrocnemius the concentration of both the labile and glycogen was unchanged. In the m. gastrocnemius of rats treated with Glypondin a significant rise in the concentration of noncollagenous protein was demonstrated.
D000818:Animals; D006003:Glycogen / Q000378:metabolism*; D008112:Liver Glycogen / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*; D011724:Pyridazines / Q000494:pharmacology*; D051381:Rats; D014018:Tissue Distribution
D008112:Liver Glycogen; D011506:Proteins; D011724:Pyridazines; C015249:Glypondin; D006003:Glycogen