[Ca2+ ion transport in the mitochondria of Ehrlich ascites tumor cells].
Peculiarities of Ca2+ accumulation in tumor mitochondria (TM) under different experimental conditions were studied. In the absence of penetrating anions TM were shown to accumulate Ca2+ five times less than liver mitochondria do, this difference being even more in the presence of acetate. pi abolishes the observed defects in Ca2+ transport while increasing considerably the Ca2+-capacity of TM. Besides, as distinct from liver mitochondria, Pi produces a stabilizing effect upon the membrane permeability of TM, which can be responsible for the increase in the TM Ca2+-capacity.
D000042:Absorption; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002118:Calcium / Q000378:metabolism*; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism / Q000648:ultrastructure*; D002413:Cations, Divalent; D002463:Cell Membrane Permeability / Q000187:drug effects; D008297:Male; D051379:Mice; D008928:Mitochondria / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000378:metabolism; D010710:Phosphates / Q000378:metabolism
D002413:Cations, Divalent; D010710:Phosphates; D002118:Calcium
Transport ionov Ca2+ v mitokhondriiakh astsitnykh opukholevykh kletok Erlikha.