Central areolar choroidal dystrophy.
Three members of a family with central areolar choroidal dystrophy showed the early and late stages of this disorder. The youngest affected was a 12-year-old girl who exhibited decreased vision, a red-green dyschromatopsia, and mild granularity of the macula with a diffuse foveal reflex. A discrete focal loss of choriocapillaris in the macula was seen on fluorescein angiography. This indicates that choriocapillaris atrophy is an early finding in this disease.
D000293:Adolescent; D001284:Atrophy; D002196:Capillaries / Q000473:pathology; D002648:Child; D002825:Chorioretinitis / Q000175:diagnosis; D002829:Choroid / Q000098:blood supply / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D005799:Genes, Dominant; D006801:Humans; D008268:Macular Degeneration / Q000151:congenital / Q000175:diagnosis / Q000235:genetics; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D010857:Pigment Epithelium of Eye; D013577:Syndrome; D014603:Uveal Diseases / Q000175:diagnosis / Q000235:genetics