[Effect of acute and chronic hypoxia on the structure of the neural elements of the brain].
In rats subjected to the effect of 10 000 m "altitude" for 2 h, numerous nerve cells in different areas of the brain (cortex of both cerebral hemispheres, cerebellum, optic thalamus, hippocamp, pons varolii) had morphological features peculiar to a reversible and irreversible dystrophic process. Similar changes were not observed in the brain of rats subjected to the effect of 9000 m "altitude" for one hour. Nerve cells in all brain areas are rich in substance of Nissl. In the rats adapted to hypoxia, as in the rats from the first experiment, the nerve cells are enlarged in their dimentions, the substnace of Nissl in their cytoplasm is seem increased. The destructive changes in neurons are scarce. Many neurons of the cortex have signs pointing to an increased activity of nucleus and nucleolus. Satallitosis and quantitative augmentation of glial cells is noted.
D000208:Acute Disease; D000531:Altitude; D000818:Animals; D001921:Brain / Q000473:pathology*; D002908:Chronic Disease; D007032:Hypothalamus, Anterior / Q000473:pathology; D000860:Hypoxia / Q000473:pathology*; D008297:Male; D009474:Neurons / Q000473:pathology*; D010296:Parietal Lobe / Q000473:pathology; D011149:Pons / Q000473:pathology; D011689:Purkinje Cells / Q000473:pathology; D051381:Rats
Nekotorye dannye o vliianii ostroĭ i khronicheskoĭ gipoksii na strukturu nervnykh elementov golovnogo mozga.