[Adaptation of the limb bones of inbred rats to physical stress following 60 days of hypokinesia].
Under study were the alterations in the extremity bones of inbred animals during 60-day-long hypokinesia. Variations of the correction of hypokinesia by physical loadings associated with the linear kind of animals were found and tested. Hypokinesia was shown to have inhibiting effects on the morphometrical parameters of flat (scapula, pelvic) and tubular (humeral, femoral, tibial) bones, the calcium and phosphorus content in blood serum being increased. Interlinear distinctions of the parameters studied under hypokinesia were revealed. The physical loading given against the background of restricted mobility normalizes the growth of bones, the level of calcium and phosphorus in the blood serum. The correction degree is dependent on the linear kind of animals speaking in favour of genotypical nature of adaptation of bones to physical loadings during hypokinesia.
D000222:Adaptation, Physiological; D000818:Animals; D001846:Bone Development; D002118:Calcium / Q000097:blood; D005121:Extremities / Q000254:growth & development*; D005269:Femur / Q000254:growth & development; D008297:Male; D009068:Movement; D010384:Pelvic Bones / Q000254:growth & development; D010758:Phosphorus / Q000097:blood; D051381:Rats; D011919:Rats, Inbred Strains; D013977:Tibia / Q000254:growth & development
D010758:Phosphorus; D002118:Calcium
Adaptatsiia kosteĭ konechnosteĭ inbrednykh krys k fizicheskim nagruzkam pri 60-sutochnoĭ gipokinezii.