The inhibition by colchicine of the initiation of DNA synthesis by hepatocytes in regenerating rat liver and by cultivated WI-38 and C3H10T1/2 cells.
D000818:Animals; D002460:Cell Line; D003078:Colchicine / Q000494:pharmacology*; D004247:DNA / Q000096:biosynthesis*; D004305:Dose-Response Relationship, Drug; D004790:Enzyme Induction / Q000187:drug effects; D006498:Hepatectomy; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008115:Liver Regeneration; D008297:Male; D009955:Ornithine Decarboxylase / Q000096:biosynthesis; D051381:Rats
D004247:DNA; D009955:Ornithine Decarboxylase; D003078:Colchicine