title: The effect of praziquantel on Echinococcus granulosus, Taenia hydatigena and Taenia ovis infections in dogs.
abstract: The effect of praziquantel on Echinococcus granulosus, Taenia hydatigena and T ovis was investigated in a trial involving 360 dogs. The drug was found to be highly toxic to tapeworms. Few dogs remained infected after a single treatment within the range of dose rates tested (0-31 mg/kg to 10-0 mg/kg body weight). No toxicity to dogs was observed.
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004443:Echinococcosis / Q000188:drug therapy / Q000662:veterinary*; D007546:Isoquinolines / Q000627:therapeutic use*; D011719:Pyrazines / Q000627:therapeutic use; D013622:Taeniasis / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D000871:Anthelmintics; D007546:Isoquinolines; D011719:Pyrazines