Nuclear magnetic resonance of nucleotide-amidates. Investigation of the secondary structure of methylester of deoxyadenylyl-(5'-3')-deoxyadenylyl-(5' leads to N)-L-phenylalanine.
The secondary structure of methyl ester of deoxyadenylyl- - (5' - 3') - deoxyadenylyl - (5' leads to N) - L-phenylalanine / L- PheOMe - d(pApA)/ was investigated using proton magnetic resonance. The folded conformation stabilized by hydrophobic interactions in aqueous solution was shown for this compound. The investigation of the chemical shifts of aromatic protons of L- PheoOMe - d(pApA) permitted us to construct the conformational model of this compound.
D003838:Deoxyadenine Nucleotides; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides; D009841:Oligonucleotides; D010649:Phenylalanine / Q000031:analogs & derivatives*
D003838:Deoxyadenine Nucleotides; D009838:Oligodeoxyribonucleotides; D009841:Oligonucleotides; D010649:Phenylalanine