title: [Biochemical and morphological changes in the uterus after the use of estradiol].
abstract: A review is given of data concerning changes in the uterus after estradiol administration. It is concluded that the time intervals between hormone administration and appearance of cellular changes cannot always be compared as they depend upon many variables, e.g. species, dose of hormone, route of application, age of animals, and time elapsed after ovariectomy. Several hypotheses on the mechanism of estrogen action are discussed.
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism; D000818:Animals; D002843:Chromatin / Q000187:drug effects; D004247:DNA / Q000096:biosynthesis; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D008938:Mitosis / Q000187:drug effects; D051381:Rats; D011960:Receptors, Estrogen / Q000378:metabolism; D013995:Time; D014599:Uterus / Q000187:drug effects*
chemical_list: D002843:Chromatin; D011960:Receptors, Estrogen; D004958:Estradiol; D004247:DNA; D012321:DNA-Directed RNA Polymerases; D000262:Adenylyl Cyclases
vernacular_title: Biochemische und morphologische Veränderungen im Uterus nach Ostradiol-Gabe.