[Neurologic accidents and oral contraceptives].
The frequency of cerebrovascular accidents in women taking oral contraceptives (OC) is at the second place after phlebitis of the legs. Arterial infarcts and transient ischaemic attacks are recorded. Their mechanisms are poorly understood. Embolism is likely. In some cases arterial dissecting aneurysms have been demonstrated or are very likely. Venous occlusions may also occur. In many cases headache or transient attacks have occured prior to the major accident. OC have more than 50 metabolic effects among which changes in antithrombin III, in serum lipids, in the chemistry of the arterial wall. Neurological evaluation is mandatory in women taking OC.
D002561:Cerebrovascular Disorders / Q000139:chemically induced*; D003276:Contraceptives, Oral / Q000009:adverse effects*; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000139:chemically induced; D010689:Phlebitis / Q000139:chemically induced; D012164:Retinal Diseases / Q000139:chemically induced
D003276:Contraceptives, Oral
Accidents neurologiques et contraceptifs oraux.