[Experimental myocardial infarct in the pig: effect of temporary ligation and revascularization on the ST segment in the epicardial ECG and on the incidence of ventricular fibrillation].
A short period of myocardial ischemia induced by temporary ligation of 2 min duration prior to occlusion of the left anterior descending branch of the left coronary artery (LAD) in the pig does not have a beneficial effect on epicardial ST-segment alterations or on the incidence of ventricular fibrillation. One-stage ligation therefore seems to be the procedure of choice in occluding the porcine LAD. In 14 of 24 animals an isolated alternans of the ST-T segment was observed during the first few minutes of occlusion. Reperfusion after 60 min caused temporary increase of the ST-segment alterations, in contrast to the findings in the dog, where revascularization causes prompt return of the ST-segment to the pre-occlusion level. In addition, ectopic rhythms were frequently observed after removal of ligation.
D000818:Animals; D003331:Coronary Vessels; D004562:Electrocardiography; D005260:Female; D008026:Ligation / Q000009:adverse effects; D009203:Myocardial Infarction / Q000209:etiology / Q000601:surgery*; D009204:Myocardial Revascularization; D013552:Swine; D014693:Ventricular Fibrillation / Q000209:etiology*
Experimenteller Myokardinfarkt beim Schwein: Einfluss von Probeligatur und Revaskularisierung auf die ST-Strecke im epikardialen Ekg. und auf die Häufigkeit von Kammerflimmern.