[Chemotherapy-radiotherapy association in the treatment of localized forms of Hodgkin's disease. Prognosis of polychemotherapy after three trials of M.O.P.P].
63 patients with Hodgkin disease of limited extent (I, II, III) are treated with two protocols: extended field irradiation versus chemotherapy (M.O.P.P.) + extended field irradiation. Three points are suggested by analysis of the results: 1) Advantage from the combination of chemotherapy-radiotherapy. 2) Resistance to chemotherapy frequent innodular sclerosis. 3) In patients treated with chemotherapy the reaction has a prognostic value: failure of treatment being seen only in patients who did not obtain a complete remission.
D004359:Drug Therapy, Combination; D006689:Hodgkin Disease / Q000188:drug therapy* / Q000532:radiotherapy / Q000628:therapy; D006801:Humans; D007813:Laparotomy; D008466:Mechlorethamine / Q000627:therapeutic use*; D011241:Prednisone / Q000627:therapeutic use*; D011344:Procarbazine / Q000627:therapeutic use*; D011379:Prognosis; D012075:Remission, Spontaneous; D014750:Vincristine / Q000627:therapeutic use*
D011344:Procarbazine; D008466:Mechlorethamine; D014750:Vincristine; D011241:Prednisone
Association chimiothérapie-radiothérapie dans le traitement des formes localisées de la maladie de Hodgkin. Valeur pronostique de la réaction à la polychimiothérapie après trois cures de M.O.P.P.