Assumptions for different ascertainment models in human genetics.
Some aspects of sampling family data in human genetics are discussed. Two well-investigated ascertainment models, the complete ascertainment model and the single ascertainment model, which have been derived using restrictive sampling assumptions, are shown to hold under four more general sets of assumptions.
D030342:Genetic Diseases, Inborn / Q000235:genetics*; D006801:Humans; D008433:Mathematics; D008954:Models, Biological; D012494:Sampling Studies; D013223:Statistics as Topic