DNA-variations in neighbouring epithelium in patients with bladder carcinoma.
Histologically atypical urothelium taken from bladder mucosa neighbouring transitional cell carcinoma showed similar, though less marked, DNA-changes as observed in the corresponding tumours. A definite increase in the number of non-diploid DNA-values was found in 6 (of 12 urothelial specimens. The clinical significance of urothelial DNA-changes is discussed.
D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D004273:DNA, Neoplasm; D004171:Diploidy; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008297:Male; D009092:Mucous Membrane / Q000473:pathology; D001743:Urinary Bladder / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000473:pathology*
D004273:DNA, Neoplasm