Effect of salbumatol on acute gastric ulceration induced by indomethacin in the rat.
Indomethacin produces gastric ulceration in the rat when given by subcutaneous injection. Salbutamol, a beta2-adrenergic agonist, provided full protection from the development of these lesions. This observation may have a bearing on the genesis and therapy of some forms of peptic ulceration.
D000208:Acute Disease; D000420:Albuterol / Q000627:therapeutic use*; D000818:Animals; D007213:Indomethacin; D008297:Male; D051381:Rats; D013276:Stomach Ulcer / Q000139:chemically induced / Q000517:prevention & control*
D000420:Albuterol; D007213:Indomethacin