[Neurohypophyseal hormones in the cerebrospinal fluid with different degrees of hydration].
Antidiuretic and oxytocic activities of venous blood plasma and liquor of ambient cistern of the cerebrum were studied in chronic experiments on alert dogs at different levels of hydration. Liquor was found to have oxytocic activity and practically no antidiuretic activity at ordinary hydration and after two days of thirst. After three days of thirst, dog's liquor caused antidiuretic reaction in rats anesthetized with alcohol, the reaction being lesser than those caused by simultaneously received plasma samples. Liquor displayed an obvious antidiuretic reaction similar to that of vasopressin after prolonged i.v. administration of hypotonic NaCl solution, while plasma samples only had the diuretic effect.
D000818:Animals; D004285:Dogs; D005260:Female; D007038:Hypotonic Solutions / Q000494:pharmacology; D008297:Male; D010121:Oxytocin / Q000097:blood / Q000134:cerebrospinal fluid*; D012965:Sodium Chloride / Q000494:pharmacology; D013894:Thirst; D013997:Time Factors; D014667:Vasopressins / Q000097:blood / Q000134:cerebrospinal fluid*; D014882:Water-Electrolyte Balance
D007038:Hypotonic Solutions; D014667:Vasopressins; D012965:Sodium Chloride; D010121:Oxytocin
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