title: [Studies on the tolerance of the organism to X 5 CrNiMo 18.10 steel (Königsee). III. Electron microscopic studies on the tissues surrounding X 5 CrNiMo 18.10 steel implants in the animal experiment].
abstract: The surrounding tissue of X 5 CrNiMo 18.10-steel implantates in guinea-pigs was analyzed by electron microscopy. Corroding products of the implantates were marked by sulfide-silver-reaction. Metallic alien material was only proven in the cells of connective tissue covering the implantates. Immediately around the implantates one can not prove products of corroding, evidently depending on their minimal size and amount. In the cells of the intermediate and the vascular zone, however, single or accumulated particles in vesicular or vacuolary organellae, resp. without membraneous cover can be demonstrated. The findings are described and discussed with regard to damages which might arise by means of alloy parts and lysosomal structures.
mesh_terms: D000818:Animals; D002857:Chromium / Q000032:analysis; D003238:Connective Tissue / Q000648:ultrastructure; D004343:Drug Implants; D006168:Guinea Pigs; D008247:Lysosomes; D009132:Muscles / Q000648:ultrastructure*; D009532:Nickel / Q000032:analysis
chemical_list: D004343:Drug Implants; D002857:Chromium; D009532:Nickel
vernacular_title: Untersuchungen zur Verträglichkeit des X 5 CrNiMo 18.10 Stahls (Königsee) im Organismus. Teil III: Elektronenmikroskopische Untersuchungen des Umgebungsgewebes von X 5 CrNiMo 18.10 Stahl-Implantaten im Tierexperiment.