Plasmalogens in arterial wall.
Plasmalogens have been determined in blood plasma, arterial and myocardial tissue of rats intubated with an atherogenic diet (vitamin D2 + cholesterol). These lipids are significantly decreased in arterial tissue after the administration of these substances for 5 consecutive days. Folic acid involved in the synthesis of plasmalogens and a powerful inhibitor of xanthine oxidase, on the contrary, increases enormously the concentration of plasmalogens in arterial tissue even with an atherogenic diet.
D000818:Animals; D001158:Arteries / Q000378:metabolism*; D004036:Diet, Atherogenic; D005492:Folic Acid / Q000494:pharmacology; D006801:Humans; D009206:Myocardium / Q000378:metabolism; D010955:Plasmalogens / Q000096:biosynthesis / Q000378:metabolism*; D051381:Rats
D010955:Plasmalogens; D005492:Folic Acid