title: Flow rates and repose  angles of wet-processed granulations.
abstract: The equation of McDougall and Evans was found not to apply to granulations. The functional relationships among volumetric powder flow rates, angles of repose, and particle size were demonstrated to exhibit maxima (rather than minima) in five common pharmaceutical granulations produced by wet processing. The angular behavior of granules (such as the experienced range of angles) is explained via supported stacking geometries, and the shallow maxima in the angle of repose versus granule diameter was derived from this model.
mesh_terms: D002626:Chemistry, Pharmaceutical; D004339:Drug Compounding / Q000379:methods; D008956:Models, Chemical; D010316:Particle Size; D011208:Powders
chemical_list: D011208:Powders