[A new case of hemoglobin J Capetown alpha 92 (FG 4) Arg replaced by gln].
Hemoglobin J Capetown was found incidentally in a patient of french origin suffering from urticaria with delayed pressure oedema. Using a preparative finger-print technique, the structural determination was easy. A functional study of the purified component confirmed the high oxygen affinity of hemoglobin J Capetown and demonstrated a low reactivity for organic phosphates. These results may explain the perturbations observed in the whole blood.
D000596:Amino Acids / Q000032:analysis; D002908:Chronic Disease; D004163:Diphosphoglyceric Acids / Q000032:analysis; D006448:Hemoglobin J / Q000032:analysis*; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans; D007525:Isoelectric Focusing; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption; D010108:Oxyhemoglobins / Q000032:analysis; D014581:Urticaria / Q000097:blood
D000596:Amino Acids; D004163:Diphosphoglyceric Acids; D006455:Hemoglobins, Abnormal; D010108:Oxyhemoglobins; D006448:Hemoglobin J
Un nouveau cas d'hémoglobine J Capetown alpha 92 (fg4) arg in equilibrium gln.