Prevention of postoperative deep-vein thrombosis by low-dose heparin in urological surgery. A double-blind, randomised study.
The efficacy of low-dose heparin in preventing deep-vein thrombosis (D. V. T.) after urological surgery was investigated in a double-blind trial. Thromboses were detected by the 125I-labelled fibrinogen technique. The incidence of D. V. T. was 36% in the control group (25 patients) and 9% in the treated group (22 patients) (p less than 0.05). Contrary to the current opinion this form of prophylaxis was effective following open prostatectomy.
D000368:Aged; D001835:Body Weight; D004311:Double-Blind Method; D005260:Female; D005340:Fibrinogen; D006493:Heparin / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D010919:Placebos; D011183:Postoperative Complications / Q000517:prevention & control*; D013924:Thrombophlebitis / Q000175:diagnosis / Q000517:prevention & control*; D014570:Urologic Diseases / Q000601:surgery
D007457:Iodine Radioisotopes; D010919:Placebos; D005340:Fibrinogen; D006493:Heparin