title: [Detection of DNA in the composition of influenza virus].
abstract: When influenza virus multiplies in chick embryos, incorporation of 3H-thymidine into virus particles is observed. The radioactivity is localized in influenza virus nucleoprotein. The analysis of 3H-thymidine-containing structures in cesium chloride density gradient permits to qualify them as DNA. Isodensity centrifugation of in vitro 125I-labeled preparation of nucleic acid from influenza virus in cesium sulphate gradient also reveals DNA molecules, in addition to RNA. A high hybridization rate of influenza virus 125I-DNA with virion RNA has been demonstrated.
mesh_terms: D002499:Centrifugation, Density Gradient; D004279:DNA, Viral / Q000032:analysis*; D009980:Influenza A virus / Q000032:analysis* / Q000378:metabolism; D009693:Nucleic Acid Hybridization; D012367:RNA, Viral; D012260:Ribonucleases; D013936:Thymidine / Q000378:metabolism
chemical_list: D004279:DNA, Viral; D012367:RNA, Viral; D012260:Ribonucleases; D013936:Thymidine
vernacular_title: Vyisvlenie DNK v sostave virusa grippa.