title: [Aneuploidy and polyploidy in the bone marrow cells of minks of different genotypes, ages and fertility].
abstract: An analysis of aneuploidy and polyploidy in bone marrow cells of female minks of different genotype and age has shown that in young minks with unsatisfactory reproductive characteristics, and in old females, the frequency of aneuploid and polyploid cells is significantly higher as compared to that in minks having a good reproductive capacity. The increase in aneuploidy level takes place mainly in the form of hypoploidy, and an increase of the frequency of polyploid cells is accompanied by a parellel increase of the proportion of cells with a low degree of ploidy. A correlation between frequencies of appearance of aneuploid and polyploid cells in minks is observed (r = 0.69 +/- 0.27). On the basis of original and bibliographic data, a hypothesis on a genetically determined instability of karyotype in mutant minks is argumented.
mesh_terms: D000367:Age Factors; D000782:Aneuploidy; D000818:Animals; D001853:Bone Marrow / Q000648:ultrastructure*; D005260:Female; D005298:Fertility; D005787:Gene Frequency; D005838:Genotype; D007621:Karyotyping; D008677:Metaphase; D008907:Mink / Q000235:genetics*; D009154:Mutation; D011123:Polyploidy
vernacular_title: Aneuploidiia i poliploidiia v kletkakh kostnogo mozga norok raznykh genotipov, vozrasta i plodovitnosti.