Influence of wind on chronic ultraviolet light-induced carcinogenesis.
Wind enhances the carcinogenic effect of chronic Iltraviolet radiation (UVL). This was demonstrated in hairless mice that were irradiated for 42 weeks with mercury are lamps. One group of animals was exposed to continuous wind flow of 2.7 m/s except for the daily I-2 min time interval when they were removed from the wind tunnel and irradiated. Another group of animals received identical irradiation but were protected from wind. The first tumour appeared in the UVL and wind group after 105 days of irradiation, and at 164 days of irradiation all surviving mice in the group had developed tumours. The group of mice receiving identical irradiation but protected from wind had their first tumour appear at 154 days of irradiation, and by 164 days of irradiation only 40% of the mice had developed tumours.
D000392:Air Movements; D000818:Animals; D005260:Female; D051379:Mice; D012878:Skin Neoplasms / Q000209:etiology*; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects*; D014919:Wind