Hemoglobin function in stored blood. XIX. Inosine maintenance of 2,3-DPG for 35 days in a CPD-adenine preservative.
This study establishes that 10 mM inosine is a sufficient additive to maintain 2,3-DPG levels in blood for five weeks of storage in CPD-adenine. No previous experiments were done with CPD-adenine (0.25 mM) using a design which would give statistical proof of the optimal concentration of inosine needed for maintenance of normal hemoglobin function (2,3-DPG) for five weeks of blood bank storage.
D000225:Adenine; D000255:Adenosine Triphosphate / Q000097:blood; D001793:Blood Preservation / Q000379:methods*; D002951:Citrates; D004163:Diphosphoglyceric Acids / Q000097:blood*; D005947:Glucose; D006454:Hemoglobins / Q000502:physiology*; D006801:Humans; D007288:Inosine / Q000008:administration & dosage / Q000494:pharmacology*; D010710:Phosphates; D013997:Time Factors
D002951:Citrates; D004163:Diphosphoglyceric Acids; D006454:Hemoglobins; D010710:Phosphates; D007288:Inosine; D000255:Adenosine Triphosphate; D005947:Glucose; D000225:Adenine