Intravitreal injections by a Dermojet syringe.
Dermojet is a spring-loaded device that injects a high velocity microspray capable of perforating the globe. An accidental intraocular injection of triamcinolone acetonide from a Dermojet syringe by a dermatologist is reported. The lack of untoward effects led to experimental intravitreal injections. The Dermojet syringe was used for intravitreal injections in 7 rabbit eyes with normal saline as the vehicle in 6 and India ink in one. There were no irreversible effects attribute to the injection noted clinically or histopathologically. While modification and further animal experimentation with this device are in order, it should not be use on human eyes at this time.
D000818:Animals; D005128:Eye Diseases / Q000209:etiology; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007277:Injections, Jet / Q000009:adverse effects; D007281:Ink; D011817:Rabbits; D012166:Retinal Hemorrhage / Q000209:etiology; D012965:Sodium Chloride / Q000008:administration & dosage; D013594:Syringes; D014822:Vitreous Body
D012965:Sodium Chloride