title: Local immunity in the pig respiratory tract. I. -- Cellular and humoral immune responses following swine influenza infection.
abstract: By serial lung washings on living pigs, kinetics of humoral and cellular local immune responses have been studied following intranasal inoculation of swine influenza virus. Local and serum antibodies appeared 8 days post-infection (p.i.) and reached a maximal titer 2 weeks p.i. Antibody titer decreased faster in lung secretions than in serum. Local and systemic cell-mediated immune responses were detected, by in vitro transformation tests, during the second week p.i.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis*; D007111:Immunity, Cellular; D009980:Influenza A virus / Q000276:immunology; D008168:Lung / Q000276:immunology*; D008213:Lymphocyte Activation; D009976:Orthomyxoviridae Infections / Q000276:immunology*; D013183:Sputum / Q000276:immunology; D013552:Swine
chemical_list: D000914:Antibodies, Viral