title: Radiation myelopathy of the lumbo-sacral spinal cord.
abstract: The clinical findings in four cases of radiation injury to the lumbosacral spinal cord and cauda equina, occuring after radiotherapy of malignant testicular tumours with radiation doses of 1597-1670 ret, are reported. The main feature in each case was a flaccid paraparesis, without sensory loss in three cases, while one patient presented a doubtful sensory deficit. Symptoms of sphincter dysfunction were absent. In all cases the symptoms caused a marked and persistent incapacity. It is suggested that the principal site of radiation injury is the proximal parts of the lower motor neuron.
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D011832:Radiation Injuries; D011879:Radiotherapy Dosage; D013119:Spinal Cord Injuries / Q000209:etiology*; D013736:Testicular Neoplasms / Q000532:radiotherapy*