title: Epidemiological investigations on arbovirus infections at Igbo-Ora, Nigeria.
abstract: A study of arbovirus infections occurring in Igbo-Ora community was carried out between May and October 1975. Haemagglutination inhibition test performed on seventy-eight human sera showed a high prevalence of antibodies against all the six arboviruses used. Percentage of positive sera were as follows: Chikungunya, (28%); Yellow fever (36%); Dengue type 1 (67%); Dengue type 2 (45%). Prevalence of HI antibodies to West Nile and Wesselsbron viruses were 44% and 59% respectively. Virus isolation studies carried out on 148 blood samples yielded three viruses: Yellow fever, Dengue type 1 and Zika. Antibody conversions to these three viruses were demonstrated in seven persons within the period of study.
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001102:Arbovirus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D001103:Arboviruses / Q000276:immunology / Q000302:isolation & purification*; D002646:Chikungunya virus / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D003716:Dengue Virus / Q000276:immunology / Q000302:isolation & purification; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D051379:Mice; D009549:Nigeria; D012328:RNA Viruses / Q000302:isolation & purification; D014902:West Nile virus / Q000276:immunology; D015005:Yellow fever virus / Q000276:immunology / Q000302:isolation & purification; D000071244:Zika Virus / Q000276:immunology / Q000302:isolation & purification
chemical_list: D000914:Antibodies, Viral