[Use of immunochemical methods in enzymology].
The binding of antibodies to enzymes-antigens markedly affects the activity and structure of the latters. The mechanisms of activation and inhibition of enzymes by antibodies and the use of immunochemical methods for the study of the active sites structure, conformational changes during interaction with substrates and other ligands and the quaternary structure of enzymes are discussed.
D000906:Antibodies / Q000494:pharmacology; D000937:Antigen-Antibody Reactions; D001665:Binding Sites; D055598:Chemical Phenomena; D002621:Chemistry; D004789:Enzyme Activation; D004791:Enzyme Inhibitors; D004798:Enzymes / Q000276:immunology / Q000378:metabolism; D007120:Immunochemistry; D011485:Protein Binding; D011487:Protein Conformation
D000906:Antibodies; D004791:Enzyme Inhibitors; D004798:Enzymes
Primenenie immunokhimicheskikh metodov v enzimologii.