title: [Use of immunochemical methods in enzymology].
abstract: The binding of antibodies to enzymes-antigens markedly affects the activity and structure of the latters. The mechanisms of activation and inhibition of enzymes by antibodies and the use of immunochemical methods for the study of the active sites structure, conformational changes during interaction with substrates and other ligands and the quaternary structure of enzymes are discussed.
mesh_terms: D000906:Antibodies / Q000494:pharmacology; D000937:Antigen-Antibody Reactions; D001665:Binding Sites; D055598:Chemical Phenomena; D002621:Chemistry; D004789:Enzyme Activation; D004791:Enzyme Inhibitors; D004798:Enzymes / Q000276:immunology / Q000378:metabolism; D007120:Immunochemistry; D011485:Protein Binding; D011487:Protein Conformation
chemical_list: D000906:Antibodies; D004791:Enzyme Inhibitors; D004798:Enzymes
vernacular_title: Primenenie immunokhimicheskikh metodov v enzimologii.