title: HLA-A3 linked C3 deficiency in multiple sclerosis.
abstract: Many workers claim variations in quantity of functional activity of several components in the complement system in M.S. patients. Studies were performed in 58 M.S. patients, typing for HLA-SD specifities and C'3 complement component. We have been able to confirm a significant correlation between the hypocomplementaemic group (31.03%) with HLA-A3. In this connection we present some considerations on complement system and M.S.
mesh_terms: D003176:Complement C3 / Q000172:deficiency*; D005260:Female; D006680:HLA Antigens; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000276:immunology*
chemical_list: D003176:Complement C3; D006680:HLA Antigens