[Fertility of semi-castrated and irradiated patients with testicular tumors].
The fertility of 62 patients has been followed up by spermatographic analysis. The patients had had malignant testicular tumors treated by semicastration and postoperative X-irradiation between 1957 and 1975. Only 52 patients produced utilizable ejaculates, and these were divided into 8 groups according to the X-ray field arrangement employed. In this way a direct correlation could be established between the field arrangement (viz. field magnitude and gonad load) and the ejaculate findings. From the results it is concluded that azoo- and oligospermia are not a hormonal change induced by the tumor but rather the consequence of X-ray damage of the spermatophores. Azoo- and oligospermia are dependent on the X-ray load on the remaining testis and on the time which has elapsed since the terminaination of treatment. About 15-20% intact fertility can still be found in these patients.
D000293:Adolescent; D000328:Adult; D005298:Fertility / Q000528:radiation effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009845:Oligospermia / Q000209:etiology; D013736:Testicular Neoplasms / Q000532:radiotherapy / Q000601:surgery*
Fertilität semikastrierter und nachbestrahlter Hodentumorpatienten.