title: [Creatine kinase isoenzyme MB and CK/GOT-ratio in the differential diagnosis of acute myocardial infarction (author's transl)].
abstract: In 56 patients with certain transmural myocardial infarction the reliability of myocard specific creatine kinase isoenzyme MB is compared with the usual estimation of creatine kinase activity in serum and the use of CK/GOT activity quotient. In measurements at different times CK-MB proves to be more reliable than other laboratory parameters: during the first 24 hours after hospital admission CK-MB indicates the infarct and correlates with ECG alterations in practically all cases. In 11 patients with CK-activity increase over 100 U/l of extracardial origin, myocardial involvement can be excluded by measuring CK-MB-activity. Formation of CK/GOT quotient shows erroneously an infarction in about half the cases.
mesh_terms: D001219:Aspartate Aminotransferases / Q000097:blood; D003402:Creatine Kinase / Q000097:blood*; D003937:Diagnosis, Differential; D004562:Electrocardiography; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D009203:Myocardial Infarction / Q000175:diagnosis / Q000201:enzymology*; D013997:Time Factors
chemical_list: D007527:Isoenzymes; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase
vernacular_title: Creatinkinase-Isoenzym MB und der Quotient CK/GOT bei der Differentialdiagnose des akuten Herzinfarktes.