Studies on the activation of a model furan compound--toxicity and covalent binding of 2-(N-ethylcarbamoylhydroxymethyl)furan.
D000818:Animals; D002219:Carbamates / Q000378:metabolism / Q000633:toxicity; D004247:DNA / Q000378:metabolism; D005663:Furans / Q000378:metabolism / Q000633:toxicity*; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects; D008168:Lung / Q000187:drug effects; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D009698:Nucleoproteins / Q000378:metabolism; D011485:Protein Binding; D051381:Rats; D013347:Subcellular Fractions / Q000378:metabolism
D002219:Carbamates; D005663:Furans; D009698:Nucleoproteins; C014540:(N-ethylcarbamoylhydroxymethyl)furan; D004247:DNA