The limitations of model systems in prostatic cancer.
The quest for an ideal model useful for designing treatment strategies as well as providing biological information is not a realistic goal. A multitude of models are required to answer a multiplicity of questions. However, given the currently available treatment modalities much can be accomplished directly in man without resorting to preclinical models.
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology; D002478:Cells, Cultured; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D006801:Humans; D008297:Male; D051379:Mice; D008819:Mice, Nude; D008954:Models, Biological; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000628:therapy; D011471:Prostatic Neoplasms / Q000628:therapy*; D051381:Rats; D014183:Transplantation, Heterologous
D000970:Antineoplastic Agents