Preparation and characterization of aflatox-n B1-1-(O-carboxymethyl) oxime.
A method is described for the preparation and purification of aflatoxin B1-1(O-carboxymethyl) oxime from aflatoxin B1. The overall yield was about 73-83%. The new aflatoxin B1 derivative was characterized by mass, ultraviolet, infrared, and nuclear magnetic resonance spectral analyses, and was nontoxic to 8-day-old chicken embryos when tested at a concentration of 3.48 microgram/egg.
D000348:Aflatoxins / Q000032:analysis* / Q000138:chemical synthesis / Q000633:toxicity; D000818:Animals; D002642:Chick Embryo; D002855:Chromatography, Thin Layer; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008722:Methods; D010091:Oximes / Q000032:analysis / Q000138:chemical synthesis; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000348:Aflatoxins; D010091:Oximes