Simple method for elimination of aminoglycosides from serum to permit bioassay of other antimicrobial agents.
Cellulose phosphate powder can be added to serum to selectively bind aminoglycosides by ionic interaction without binding or inactivation of the penicillins, the cephalosporins, clindamycin, vancomycin, chloramphenicol, or trimethoprim. This simple, rapid technique permits the measurement of non-aminoglycoside antibiotics in the presence of aminoglycosides.
D000617:Aminoglycosides / Q000097:blood*; D000890:Anti-Infective Agents / Q000097:blood*; D001681:Biological Assay / Q000379:methods; D002482:Cellulose; D006801:Humans; D008722:Methods
D000617:Aminoglycosides; D000890:Anti-Infective Agents; D002482:Cellulose