title: The effect of parasympathetic nervous system on hydrodynamics of intraocular fluids and distribution of electrolytes and amino acids.
abstract: Tonographic determinations Po and C), cannulation of the anterior chamber and measurements of the secreted aqueous humor volume by the method of posterior-anterior chamber perfusion with inulin solution were carried out in normal eyes, in eyes after parasympathetic denervation and during the action of a cholinergic neurotransmitter under the conditions of postdenervation hyperexcitability. Parasympathetic denervation of the eyeball was obtained by excision of the ciliary ganglion. Additonally, pharmacological blockade of the adrenergic neurons was applied. In the aqueous humor from the posterior and anterior chamber osmolality, as well as concentrations of sodium potassium, calcium, magnesium and total alpha-amino nitrogen were determined. The cholinergic effect on the volume of secreted aqueous humor and on the channels of its outflow was described. This effect was enhanced by the postdenervation hyperexcitability state, indicating a stimulating parasympathetic influence on the passage of electrolytes and amino acids into the intraocular fluids.
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D000867:Anterior Chamber / Q000294:innervation; D001082:Aqueous Humor / Q000378:metabolism* / Q000502:physiology; D003714:Denervation; D004573:Electrolytes / Q000378:metabolism*; D005123:Eye / Q000294:innervation* / Q000378:metabolism*; D007429:Intraocular Pressure; D010275:Parasympathetic Nervous System / Q000502:physiology*; D011817:Rabbits
chemical_list: D000596:Amino Acids; D004573:Electrolytes