Granuloma annulare with transfollicular perforation.
In recent years the phenomenon of transepithelial elimination has been found to be the underlying mechanism in a variety of skin disorders. "Perforating dermatoses" may show transepidermal or transfollicular elimination or a combination of the two. A case of papular granuloma annulare is reported, where in one lesion the pilary apparatus actively participated in the elimination of necrobiotic collagen from the dermis. To our knowledge, perforating granuloma annulare with a transfollicular pathway has not previously been described. Also, a classification of perforating dermatoses is presented.
D000368:Aged; D004817:Epidermis / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D006099:Granuloma / Q000473:pathology*; D006801:Humans; D008297:Male; D012871:Skin Diseases / Q000473:pathology*