[Effect of BCG on the growth of Krebs-2 carcinoma].
BCG vaccine inhibits the growth of intramuscular transplants of Krebs-2 carcinoma, when given in mixture with the tumor cells, and stimulates it in contralateral administration. When BCG and the tumor cells are injected separately in the region, drained by one and the same lymph node, no antitumor effect of the vaccine is observed. It is suggested that BCG effect on experimental tumor growth is mainly based not on the immunological mechanisms, but is the result of redistribution of cells participating in nonspecific antitumor resistance.
D000818:Animals; D001500:BCG Vaccine / Q000008:administration & dosage / Q000627:therapeutic use*; D002287:Carcinoma, Krebs 2 / Q000188:drug therapy*; D002455:Cell Division / Q000187:drug effects; D005260:Female; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D009368:Neoplasm Transplantation
D001500:BCG Vaccine
O vliianii BTsZh na rost kartsinomy Krebs-2.