Rat bile as a convenient source of secretory IgA and free secretory component.
Rat hepatic bile contains three proteins as major constituents: secretory IgA (SIgA), free secretory component (FSC) and albumin. Traces of alpha-macroglobulin, transferrin, IgG and IgM are also detectable. The bile duct daily pours between 5-12 mg each of SIgA and FSC into the rat duodenum. The origin and function of these proteins in bile may represent important clues in the understanding of the SIgA system.
D000818:Animals; D001646:Bile / Q000276:immunology*; D002850:Chromatography, Gel; D007122:Immunoelectrophoresis; D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D007128:Immunoglobulin Fragments; D008892:Milk / Q000276:immunology; D051381:Rats; D012635:Secretory Component
D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D007128:Immunoglobulin Fragments; D012635:Secretory Component