Effects of some oligopeptides, consisting of aromatic amino acids, on the excitability of an identifiable giant neurone of an African giant snail (Achatina fulica Férussac).
L-Phe-L-Tyr and L-Lys-L-Phe-L-Tyr showed a marked inhibitory effect (not chloride-dependent) on the excitability of an identifiable giant neurone (the TAN) of Achatina fulica Férussac, while L-Tyr-L-phe, L-Tyr-L-Tyr, L-Phe-L-Phe, L-Lys-L-Phe and Z-L-Phe-L-Tyr (Z-: carbobenzoxy) had no effect.
D000818:Animals; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects; D009433:Neural Inhibition; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D009842:Oligopeptides / Q000494:pharmacology*; D012908:Snails
D009842:Oligopeptides