title: Cerebral edema.
abstract: Great strides have been made in understanding the pathogenesis of cerebral edema. Treatment is usually successful, particularly with the newer modes of management (mannitol, steroids, hyperventilation); however, cerebral edema is occasionally resistant to all modes of therapy. At that point, no treatment is effective; even if the patient does survive, he is left with a major severe neurological deficit. Future research must be directed toward methods of reversing this presently untreatable state.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001812:Blood-Brain Barrier; D001921:Brain / Q000473:pathology; D001929:Brain Edema / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D005990:Glycerol / Q000627:therapeutic use; D006801:Humans; D006982:Hypertonic Solutions / Q000627:therapeutic use; D007427:Intracranial Pressure; D008353:Mannitol / Q000627:therapeutic use; D014508:Urea / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D006982:Hypertonic Solutions; D008353:Mannitol; D014508:Urea; D005990:Glycerol