Serum levels and urinary concentrations of kanamicin, bekanamicin and amikacin (BB-K8) in diabetic children and a control group.
Serum levels of kanamicin, bekanamicin, and amikacin were studied, after a single intramuscular dose of each antibiotic, in three groups of diabetic children, with their respective normal controls, paired by age, weight and sex. Lower serum levels were observed with kanamicin and bekanamicin in diabetic children compared to their controls. The difference in low serum levels was less noticeable with amikacin.
D000293:Adolescent; D000583:Amikacin / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism / Q000652:urine; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism*; D006801:Humans; D007612:Kanamycin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000097:blood / Q000378:metabolism* / Q000652:urine
D007612:Kanamycin; D000583:Amikacin