title: [Composition of cerebrospinal fluid protein in children with nervous system diseases according to disc-electrophoresis in polyacrylamide gel].
abstract: The author studied the fractional content of proteins in the CSF in 105 children with different disorders of the nervous system and 35 children of a control group (aged 2-13 years) with the aid of disc-electrophoresis in polyacrylamide gel. The proteins of the CSF were studied in encephalitis, polyradiculoneuritis, cerebral arachnoiditis, brain tumors and epilepsy. The content of total proteins in the CSF in 42% of the studied children did not differ significantly from the usual age norm. More distinct changes were found in proteinogramms of the CSF where 14 protein fractions were singled out. It was established that a change in the content of separate fractions, their intercorrelation depended on the character of the pathological process.
mesh_terms: D000293:Adolescent; D000418:Albumins / Q000134:cerebrospinal fluid; D001100:Arachnoiditis / Q000134:cerebrospinal fluid; D001932:Brain Neoplasms / Q000134:cerebrospinal fluid; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004589:Electrophoresis, Disc; D004660:Encephalitis / Q000134:cerebrospinal fluid; D004827:Epilepsy / Q000134:cerebrospinal fluid; D005916:Globulins / Q000134:cerebrospinal fluid; D006801:Humans; D009422:Nervous System Diseases / Q000134:cerebrospinal fluid*; D011128:Polyradiculopathy / Q000134:cerebrospinal fluid; D014168:Transferrin / Q000134:cerebrospinal fluid
chemical_list: D000418:Albumins; D002556:Cerebrospinal Fluid Proteins; D005916:Globulins; D014168:Transferrin
vernacular_title: Osobennosti sostava belkov spinnomozgovoĭ zhidkosti pri zabolevaniiakh nervnoĭ sistemy u deteĭ po dannym disk-élektroforeza v poliakrilamidnom gele