Multiple mucosal neuroma (MMN) or multiple endocrine neoplasia (MEN) type 3 syndrome. Ocular manifestations: a case report.
Case report of a young man showing neuromas of the palpebral and bulbar conjunctiva and markedly thickened nerve fibers in both cornea. Multiple neuromas were seen on the lips and in the oral cavity. A medullary carcinoma of the thyroid was found. These symptoms pointed to the diagnosis of a MMN or MEN type 3 syndrome. There were no signs of phaeochromocytoma, however, which also belongs to this syndrome. The ophthalmologist, who may be the first to see such a patient as a child, should be aware of the malignancies which develop around puberty and of the strong and dominant heredity of this disease.
D000328:Adult; D002277:Carcinoma / Q000150:complications*; D005134:Eye Neoplasms / Q000150:complications*; D006801:Humans; D008297:Male; D009062:Mouth Neoplasms / Q000150:complications; D009092:Mucous Membrane; D009378:Neoplasms, Multiple Primary; D009463:Neuroma / Q000150:complications*; D013577:Syndrome; D013964:Thyroid Neoplasms / Q000150:complications*