[Study of the androgenic activity of the ovaries in various forms of virilism of ovarian etiology].
The authors present the results of determination of the testosterone level in the blood by the method of competitive fixation by proteins under conditions of a functional test with the depression of the adrenal cortex function with dexamethazone and stimulation of the ovarian function with choriogonin against this background in patients with the virile syndrome of ovarian genesis. Three groups of patients with the ovarian hyperandrogenia were distinguished. Changes in the blood testosterons level under the test conditions confirmed objectively the ununiformity of of this syndrome and permitted one to characterize the hormonal activity of the androgen-producing structures of the ovaries and their sensitivity to choriogonin stimulation in patients of different groups. The functional test with the determination of the blood testosterone level can be applied under clinical conditions for detection of the source and the degree of hyperandrogenia.
D000858:Anovulation / Q000150:complications / Q000503:physiopathology; D005260:Female; D006801:Humans; D010050:Ovarian Function Tests / Q000379:methods; D010053:Ovary / Q000503:physiopathology*; D013739:Testosterone / Q000097:blood / Q000378:metabolism*; D014770:Virilism / Q000209:etiology / Q000503:physiopathology*
D013739:Testosterone
Izuchenie androgennoĭ aktivnosti iaichnikov pri razlichnykh formakh viril'nogo sindroma ovarial'nogo geneza.