title: Effect of citrinin, a mycotoxin produced by Penicillium citrinum, on laying hens and young broiler chicks.
abstract: Citrinin fed to mature laying hens at levels of 0, 50, and 250 mug/g. of diet for three weeks had no effect on body weight, feed consumption, egg production, egg weight or egg shell quality. A moderate diarrhea occurring about three days after feeding 250 mug. citrinin/g. of diet was observed. However, the diarrhea subsided once the birds were returned to a normal diet. Young broiler chicks were fed a diet containing either 0, 62.5, 125, 250, or 500 mug. citrinin/g. of diet from hatching to three weeks of age. Body weight was decreased by the 500 mug/g. level whereas all levels of citrinin resulted in enlarged kidneys and an improvement in feed conversion when compared to control values. There was also a slight dose-related increase in liver size. The 250 and 500 mug./g. levels resulted in a dose-related increase in water consumption accompanied by an acute diarrhea. Dietary citrinin had no effect on serum protein, glucose, cholesterol, uric acid, calcium, potassium and sodium concentrations or packed cell volume.
mesh_terms: D000821:Animal Feed; D000818:Animals; D001578:Benzopyrans / Q000633:toxicity*; D001835:Body Weight; D002645:Chickens; D002953:Citrinin / Q000633:toxicity*; D003967:Diarrhea / Q000139:chemically induced / Q000662:veterinary; D004531:Eggs; D005260:Female; D008297:Male; D010058:Oviposition; D011201:Poultry Diseases / Q000139:chemically induced*
chemical_list: D001578:Benzopyrans; D002953:Citrinin