Adult haemoglobin in developmentally retarded tadpoles of Xenopus laevis.
Tadpoles of Xenopus laevis reared in water containing 0-01% propylthiouracil continue to grow but fail to develop or metamorphose. The haemoglobin of such tadpoles has been extracted in buffer, converted to a cyanmet form, and run on polyacrylamide gels. The developmentally retarded tadpoles are found to possess adult-type haemoglobin rather than the tadpole type which normally characterizes their developmental stage.
D000818:Animals; D006454:Hemoglobins / Q000378:metabolism*; D007814:Larva; D008675:Metamorphosis, Biological / Q000187:drug effects; D011441:Propylthiouracil / Q000494:pharmacology; D014981:Xenopus / Q000097:blood* / Q000254:growth & development
D006454:Hemoglobins; D011441:Propylthiouracil