A cell line (SCABER) derived from squamous cell carcinoma of the human urinary bladder.
An established cell line derived from a documented squamous cell carcinoma of human urinary bladder is described. The cultured cells retained the characteristic morphology of the tumor of origin for 40 in vitro passages. Numerous desmosomes were found between cultured cells. Chromosome analysis showed hypotetraploidy with no obvious modal number, while distinctive marker chromosomes and a male karyotype were present.
D000256:Adenoviridae / Q000302:isolation & purification; D002294:Carcinoma, Squamous Cell / Q000235:genetics / Q000473:pathology*; D002460:Cell Line; D002478:Cells, Cultured; D002875:Chromosomes; D003593:Cytoplasm / Q000648:ultrastructure; D003896:Desmosomes / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008875:Middle Aged; D009174:Mycoplasma / Q000302:isolation & purification; D011123:Polyploidy; D001749:Urinary Bladder Neoplasms / Q000235:genetics / Q000473:pathology*