Effects of locoweed toxin on rats.
Rats fed pellets containing locoweed developed typical microscopic lesions of locoweed poisoning. Rats fed a water extract of locoweed or urine from sheep given locoweed also developed microscopic lesions. This indicated that the locoweed toxin is water soluble and is excreted in the urine.
D000818:Animals; D001681:Biological Assay / Q000379:methods; D007674:Kidney Diseases / Q000652:urine / Q000662:veterinary; D007687:Kidney Tubules, Proximal / Q000473:pathology; D010939:Plant Poisoning / Q000473:pathology / Q000652:urine / Q000662:veterinary*; D051381:Rats; D012756:Sheep; D012757:Sheep Diseases / Q000473:pathology / Q000652:urine*; D014118:Toxins, Biological / Q000652:urine*
D014118:Toxins, Biological