[Assessment of the findings of fibrogastroscopy with gastrobiopsy and determination of hexokinase activity in the serum and gastric juice of stomach ulcer patients].
To compare the results of fibrogastroscopic study and to determine the activity of hexokinase (HK) in gastric juice 113 persons were examined 89 of them having ulcerous disease. The control group comprised 24 healthy individuals. The data obtained indicated that in the control group the activity of HK was not found in any portion of the gastric juice. In patients with ulcerous disease the presence of the enzyme was noted in 36 of 89 subjects. In two of them malignant transformation of the ulcer was observed. Patients with gastric ulcer, who show HK activity in any gastric juice portion, seem to be assessed as gastric cancer high-risk group.
D000328:Adult; D004796:Clinical Enzyme Tests; D005260:Female; D005750:Gastric Juice / Q000201:enzymology*; D006593:Hexokinase / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012306:Risk; D013274:Stomach Neoplasms / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D013276:Stomach Ulcer / Q000097:blood / Q000150:complications*
D006593:Hexokinase
Otsenka dannykh fibrogastroskopii s gastrobiopsieĭ i opredeleniia aktivnosti geksokinazy v syvorotke i zheludochnom soke bol'nykh iazvoĭ zheludka