Massive intracerebellar hemorrhage in low-birth-weight infants.
The clinical and pathologic observations of massive intracerebellar hemorrhage (destruction of at least one-third of cerebellar tissue) are described in six low-birth-weight infants. In all infants, severe progressive apnea associated with a falling hematocrit were the prominent clinical features. Four infants were asphyxiated at birth. Some degree of cerebellar hemorrhage (macroscopic or microscopic) was observed in 21% of 157 newborn brains examined at autopsy. The cause of massive intracerebellar hemorrhage is unknown, but may result from deforming pressures on the skull secondary to perinatal trauma. A close follow-up of cerebellar function in low-birth-weight infants is important.
D001724:Birth Weight; D002525:Cerebellar Cortex / Q000473:pathology; D002531:Cerebellum / Q000473:pathology*; D002543:Cerebral Hemorrhage / Q000473:pathology*; D002552:Cerebral Ventricles / Q000473:pathology; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000473:pathology*; D008297:Male; D012127:Respiratory Distress Syndrome, Newborn / Q000473:pathology; D013345:Subarachnoid Hemorrhage / Q000473:pathology