[Relation between oxidation and phosphorylation in gastric mucosa mitochondria].
The authors studied the state of cell respiration and oxidative phosphorylation in the mitochondria of the gastric mucosa at various phases of its function. Stimulation of secretion with histamine led to a distinct increase in the rate of mitochondrial respiration in the gastric mucosa against the background of a marked fall of the conjugation coefficient level, including P/O. The mentioned changes in the energy conjugation of mitochondria of the parietal cells preceeded activation of HCl secretion.
D000818:Animals; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism*; D006632:Histamine / Q000494:pharmacology; D066298:In Vitro Techniques; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism*; D010085:Oxidative Phosphorylation / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats; D013268:Stimulation, Chemical
D006632:Histamine
Sootnoshenie okisleniia i fosforilirovaniia v mitokhondriiakh slizistoĭ obolochki zheludka