Localization of the human GLO gene locus.
Data on the linkage relation between the GLO locus and the HLA, Bf, and PGM3 loci are presented. The family material includes 49 GLO/HLA-B (and/or Bf) segregating matings with 134 children informative on 199 parental meioses. Of phase-known meioses, 3 are recombinants and 75 nonrecombinants; linkage is therefore proven. From the total material a distance of 2.5 cM between GLO and HLA-B/Bf is calculated; and from the segregation in some informative family groups it is shown that GLO is situated between PGM3 and HLA-B/Bf.
D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X; D008040:Genetic Linkage; D006680:HLA Antigens; D006801:Humans; D007791:Lactoylglutathione Lyase / Q000097:blood*; D008190:Lyases / Q000097:blood*; D010375:Pedigree; D010733:Phosphoglucomutase
D006680:HLA Antigens; D008190:Lyases; D007791:Lactoylglutathione Lyase; D010733:Phosphoglucomutase