[Late replicating human X-chromosome in the early S-period].
The early S-period in cultured human lymphocytes was studied using the premature chromosome condensation technique. In the lymphocytes, isolated from females but not from males, one uncondensed G1-chromosome was detected among "pulverized" chromosomes which remained unlabeled with H3-thymidine. This chromosome is regarded as an inactivated X-chromosome. The data obtained are in agreement with the phenomenon of the delayed onset of DNA replication in the inactivated X-chromosomes.
D002478:Cells, Cultured; D004261:DNA Replication; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D008938:Mitosis; D012730:Sex Chromosomes
Pozdno replitsiruiushchaiasia X-khromosoma cheloveka v rannem S-periode