Post-thoracotomy intercostal block: comparison of its effects on pulmonary function with those of intramuscular meperidine.
Study of 34 patients who had undergone thoracotomy revealed that the group given intercostal nerve block analgesia had a significantly smaller decline in vital capacity after operation than did the group given narcotic analgesia only. The postoperative increase in arterial CO2 tension of the nerve block group also was significantly smaller than that of the narcotic group. The study suggests that intercostal nerve block for post-thoracotomy analgesia offers some advantage in preserving effort-dependent pulmonary function when compared with postoperative narcotic analgesia.
D000771:Anesthesia, Intravenous; D002045:Bupivacaine / Q000494:pharmacology; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D007367:Intercostal Nerves / Q000187:drug effects*; D008168:Lung / Q000502:physiology*; D008614:Meperidine / Q000008:administration & dosage / Q000494:pharmacology*; D008875:Middle Aged; D009407:Nerve Block; D012129:Respiratory Function Tests; D013900:Thoracic Nerves / Q000187:drug effects*; D013903:Thoracic Surgery; D013909:Thorax / Q000601:surgery*; D013997:Time Factors
D008614:Meperidine; D002045:Bupivacaine; D004837:Epinephrine