title: [Ultrastructural localization of lysosomal and nuclear beta-glycerophosphatase activity in the urethral discharge cells of gonorrhea].
abstract: Activity of acid phosphotase in the urethra discharge in patients with various forms of gonorrhea (acute, torpid, and chronic) was studied with the use of electron-microscopy and biochemical methods. A positive reaction of nuclei of the epithelial cells to acid phosphotase in lysosomes and perichromatin granules was demonstrated. In polymorphononuclear leucocytes the positive reaction to acid phosphotase could be also sometimes observed in granules of the cytoplasm. The electronograms presented testify to heterogeneity and high activity of acid phosphotase in lysosomes. Neither electron-microscopy nor biochemical methods could help reveal any differences in the activity of acid phosphotase in various forms of gonorrhea.
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D000208:Acute Disease; D002467:Cell Nucleus / Q000201:enzymology; D002908:Chronic Disease; D003594:Cytoplasmic Granules / Q000201:enzymology; D004848:Epithelium; D006069:Gonorrhea / Q000201:enzymology*; D006098:Granulocytes / Q000201:enzymology / Q000648:ultrastructure; D006801:Humans; D008247:Lysosomes / Q000201:enzymology; D008297:Male; D014521:Urethra / Q000166:cytology
chemical_list: D000135:Acid Phosphatase
vernacular_title: Ul'trastrukturnaia lokalizatsiia beta-glitserofosfataznoĭ aktivnosti lizosom i iader kletok otdeliaemogo uretry pri gonoreĭnoĭ infektsii