The failure to survive of autogenous free grafts of whole gracilis muscles in dogs.
An experimental study was undertaken to define the limits in size (if any) of successful free autogenous grafts of skeletal muscle. In 8 dogs, 16 gracilis muscle grafts were transplanted to the contralateral hind limb. The left hind limb served as a control for the right side, which contained paralyzed muscle. Macroscopic, microscopic, and EMG analyses demonstrated a complete failure of the free muscle grafts to take and survive. We have shown that one can exceed the limitations to the size of a successful muscle graft. Perhaps future investigators will define exactly what the maximum viable size is.
D000818:Animals; D004285:Dogs; D006084:Graft Rejection; D006614:Hindlimb; D009132:Muscles / Q000473:pathology / Q000637:transplantation*; D014182:Transplantation, Autologous