Therapeutic relevance of differences in the structural specificity of the transport systems for folate analogs in L1210 tumor cells and in isolated murine intestinal epithelial cells.
D000630:Aminopterin / Q000378:metabolism* / Q000494:pharmacology; D000818:Animals; D001693:Biological Transport, Active; D004848:Epithelium / Q000378:metabolism; D066298:In Vitro Techniques; D007421:Intestine, Small / Q000378:metabolism*; D007700:Kinetics; D007939:Leukemia L1210 / Q000188:drug therapy / Q000378:metabolism*; D008297:Male; D008727:Methotrexate / Q000031:analogs & derivatives* / Q000378:metabolism* / Q000494:pharmacology; D051379:Mice; D013329:Structure-Activity Relationship
D000630:Aminopterin; D008727:Methotrexate