Radiation-induced delay of nuclear pore formation.
We have shown that radiation affects the nuclear envelope, a membrane structure-closely associated with DNA. The density of nuclear pores visible on freeze-etch surfaces decreased at a rate of 0.042 (pores/mum2)/100 rad with respect to unirradiated cells. This is interpreted as a radiation-induced delay in development of the nuclear envelope.
D002455:Cell Division; D002460:Cell Line; D002467:Cell Nucleus / Q000528:radiation effects* / Q000648:ultrastructure; D008566:Membranes / Q000528:radiation effects*; D011830:Radiation Effects