[ Intermittent, longterm polychemotherapy in combination with radical operation of bronchial carcinoma (author's transl)].
A preliminary evaluation of a randomized, prospective clinical study of combined polychemotherapy in bronchial carcinoma is presented. The comparison of survival-curves shows a positive tendency in favor of the treatment and justifies the continuation and extension of the study. The data presented are based on the findings of 106 patients who underwent radical surgical operations due to bronchial carcinoma and of 114 patients as a comparison who in addition received aftertreatment with high doses of cytostatics applied intermittently. The importance of the influence of the clinical symptoms on the prognosis and on the effect of the Chemotherapy is emphasized.
D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001984:Bronchial Neoplasms / Q000188:drug therapy / Q000601:surgery*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy*; D013997:Time Factors; D014747:Vinblastine / Q000627:therapeutic use
D000970:Antineoplastic Agents; D014747:Vinblastine; D003520:Cyclophosphamide; D008727:Methotrexate
Intermittierende, langdauernde Polychemotherapie nach Radikaloperation des Bronchuskarzinoms