Ultrastructure of unusual cytoplasmic inclusions in a case of myeloproliferative disorder.
An unusual case of myeloproliferative disorder in which mature and immature myeloid cells were found to contain unusual cytoplasmic inclusions is reported. By light microscopy, these inclusions could be observed with Wright's stain. By electron microscopy they appeared to consist of a pale, finely granular material without surrounding membranes. Although their exact nature remains unknown, we speculate that they may represent the results or products of autophagocytosis of a portion of degenerated cytoplasm.
D000368:Aged; D003594:Cytoplasmic Granules / Q000648:ultrastructure*; D006098:Granulocytes / Q000648:ultrastructure; D006801:Humans; D008297:Male; D009196:Myeloproliferative Disorders / Q000097:blood / Q000473:pathology*