title: Studies on aminophenazone and phenobarbital release from suppositories prepared on different bases.
abstract: Employing in the studies in vitro the dynamic system, we investigated aminophenazone (APH) and phenobarbital (PHB) release through semipermeable membrane from suppositories prepared on different bases, namely. Massupol, Oleum Cacao, H-15 Witepsol, Imhausen Suppositorien Masse SB, 1500 polioxyethylene glycol. The rate of APH liberation was highest from Imhausen and lowest from H-15 Witepsol; PHB was released most rapidly from Oleum Cacao, the poorest results being observed in the case of polioxyethylene glycol.
mesh_terms: D000632:Aminopyrine / Q000032:analysis; D004058:Diffusion; D005079:Excipients; D008567:Membranes, Artificial; D010634:Phenobarbital / Q000032:analysis; D013488:Suppositories; D013997:Time Factors
chemical_list: D005079:Excipients; D008567:Membranes, Artificial; D013488:Suppositories; D000632:Aminopyrine; D010634:Phenobarbital