title: [The effect of pentobarbital sodium on mouse fibroblasts in vitro].
abstract: In mouse fibroblasts grown during a period of 48 h in a medium containing between 0.3 and 4.8 mMoles of sodium pentobarbital, there appeared diminished replication, some stathmokinesia, and plain toxicity. In further cells of this kind, taken from fetuses which had been treated with sodium pentobarbital via the dam, cell multiplication, lethality, and mitotic rate did not differ from those of control cells.
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D004622:Embryo, Mammalian; D005260:Female; D005347:Fibroblasts / Q000187:drug effects* / Q000648:ultrastructure; D066298:In Vitro Techniques; D051379:Mice; D008815:Mice, Inbred Strains; D008938:Mitosis / Q000187:drug effects*; D010424:Pentobarbital / Q000494:pharmacology* / Q000633:toxicity; D011123:Polyploidy; D014228:Triaziquone / Q000494:pharmacology
chemical_list: D014228:Triaziquone; D010424:Pentobarbital
vernacular_title: Die Wirkung von Pentobarbital-Natrium auf Mäusefibroblasten in vitro