The transport of endogenous vitamin B12 in normal human serum.
1. Serum from normal subjects has been chromatographed on Sephadex G-200 columns and the fractions containing transcobalamins 0, I and II have been identified. 2. The fractions corresponding to transcobalamin I contained, on average, 90% of the endogenous vitamin B12. Only 3% was attached to transcobalamin 0, and 7% was bound to transcobalamin II.
D000328:Adult; D001692:Biological Transport; D002850:Chromatography, Gel; D005260:Female; D006801:Humans; D008297:Male; D014155:Transcobalamins / Q000378:metabolism; D014805:Vitamin B 12 / Q000097:blood* / Q000302:isolation & purification
D014155:Transcobalamins; D014805:Vitamin B 12