Studies of low molecular weight RNA from cells infected with adenovirus 2. II. Heterogeneity at the 5' end of VA-RNA I.
The 5'-terminal sequences of VA-RNA I produced in cells infected with adenovirus 2 were analyzed. The RNA contained a mixture of mono-, di-, and triphosphate ends. The largest part of the RNA has 5'-terminal mono-, di-, or triphosphoguanylic acid, but a portion of the RNA has a 5'-terminal mono-, di-, or triphosphoadenylic acid. An RNA with 5'-terminal adenylic acid was purified and gave the same oligonucleotide map as the major form of VA-RNA I, except for the 5'-terminal products. We therefore conclude that transcription of VA-RNA I can initiate at two different nearby sites.
D000227:Adenine Nucleotides / Q000032:analysis; D000256:Adenoviridae; D001483:Base Sequence; D006150:Guanine Nucleotides / Q000032:analysis; D009843:Oligoribonucleotides / Q000032:analysis; D012367:RNA, Viral; D014158:Transcription, Genetic
D000227:Adenine Nucleotides; D006150:Guanine Nucleotides; D009843:Oligoribonucleotides; D012367:RNA, Viral