Obstetric complications after treatment of intrauterine synechiae (Asherman's syndrome).
This review comprises 36 patients who were treated for Asherman's syndrome from 1968 to 1974 at the Sloane Hospital for Women. Of the 18 patients who later conceived only 6 had uncomplicated term deliveries. Four had premature deliveries resulting in neonatal death. Three had placenta accreta and postpartum hemorrhage, necessitating a cesarean hysterectomy in 1. Two patients required cesarean section for complications due to the syndrome, 2 had spontaneous abortion, and 1 had a cervical pregnancy requiring total hysterectomy. Only 10 babies survived. The incidence and severity of complications in conceptions following treatment for Asherman's syndrome is high, and the obstetrician must be prepared to manage them.
D000026:Abortion, Habitual / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D000328:Adult; D004107:Dilatation and Curettage; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007434:Intrauterine Devices; D008599:Menstruation Disturbances / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology; D013577:Syndrome
D004967:Estrogens