Control of bleb fibrosis after glaucoma surgery by anti-inflammatory agents.
The methods used to identify and evaluate anti-inflammatory agents, and the effects of a triple drug regimen, consisting of oral prednisone and flufenamic acid and topical l-adrenaline in controlling bleb inflammation and fibrosis around drainage implants in patients with terminal glaucoma are described. The benefits of anti-inflammatory agents in other surgical glaucoma procedures are suggested.
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D004322:Drainage; D004359:Drug Therapy, Combination; D004837:Epinephrine / Q000627:therapeutic use; D005128:Eye Diseases / Q000188:drug therapy; D005439:Flufenamic Acid / Q000627:therapeutic use; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use; D012590:Sclera
D000893:Anti-Inflammatory Agents; D005439:Flufenamic Acid; D011241:Prednisone; D004837:Epinephrine