title: Adverse reaction to intravenous fluorescein: evidence for sex difference.
abstract: Males react adversely more frequently than females to intravenous fluorescein angiography, as shown in a study of 547 patients. Approximately 10% of all cases reacted: 12.8% of the male patients and 7.3% of the female patients had adverse responses. Nausea was most common; vomiting was infrequent, and urticaria rare (1.1%). Ten males as opposed to one female reacted markedly. More serious reactions did not occur during the 7 year testing period. No apparent cause for the increased frequency in the male cases was found.
mesh_terms: D005260:Female; D005451:Fluorescein Angiography / Q000009:adverse effects*; D005452:Fluoresceins / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D009325:Nausea / Q000139:chemically induced; D011537:Pruritus / Q000139:chemically induced; D012737:Sex Factors; D014839:Vomiting / Q000139:chemically induced
chemical_list: D005452:Fluoresceins