Abnormal urogenital organs occurring spontaneously in inbred ACI and Kyoto-notched rats.
Spontaneous malformations of urogenital organs found in inbred rat foetuses of ACI/NHok strains were further investigated with a postnatal survey involving other inbred strains. A new type of malformation occurred in Kyoto-notched rats. The present findings suggested that the malformations have different hereditary characteristics caused by different maldevelopmental mechanisms and are probably due to recessive polygenes.
D000818:Animals; D005260:Female; D007668:Kidney / Q000002:abnormalities; D008297:Male; D051381:Rats; D011912:Rats, Inbred ACI; D011919:Rats, Inbred Strains; D012376:Rodent Diseases / Q000151:congenital*; D013737:Testis / Q000002:abnormalities; D014564:Urogenital Abnormalities; D014599:Uterus / Q000002:abnormalities