[Influence of 2-mercaptoethylguanidine on blood pressure reaction to bradykinine and kallidine in normal and spinal rats].
2-Mercaptoethylguanidine (MEG) enhances the hypotension reaction to bradykinine and kallidine injections. In normal and spinal rats the secondary rise of the blood pressure after bradykinine, caused by catecholamine liberation, was transformed into a hypotension through MEG. These effects are partially interpreted as sympatholytic effects of MEG.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D001920:Bradykinin / Q000494:pharmacology*; D003655:Decerebrate State; D004347:Drug Interactions; D006146:Guanidines / Q000494:pharmacology*; D007022:Hypotension / Q000139:chemically induced; D007609:Kallidin / Q000494:pharmacology*; D008297:Male; D051381:Rats
D006146:Guanidines; D007609:Kallidin; D001920:Bradykinin
Beeinflussung der Blutdruckreaktion auf Bradykinin und Kallidin durch 2-Mercaptoäthylguanidin (MEG, AET) bei normalen und Spinalratten