Pharmacokinetics of frusemide in chronic renal failure.
1 The pharmacokinetics of frusemide have been studied in thirteen patients with severe chronic renal failure by using 35 S-frusemide. 2 The abosrption of aqueous frusemide was 57 +/- 20 percent (SD) and the bioavailability of 500 mg tablets was 42 +/- 12 percent, this differnece not assuming significance. 3 The renal clearance of frusemide was negligible (1.45 +/- 1.7 ml/min).
D000042:Absorption; D000328:Adult; D005665:Furosemide / Q000378:metabolism*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism*; D007700:Kinetics; D008875:Middle Aged; D013462:Sulfur Radioisotopes
D013462:Sulfur Radioisotopes; D005665:Furosemide