[Morphokinetic reactions in the adrenal gland of the albino rat after anaesthesia with inactin (author's transl)].
A marked decrease in the nuclear size in the adrenal medulla and a slight increase in the nuclear volume of the zona glomerulosa was found in the Inactin anaesthetized Wistar rat. The nuclear volumes in the zona fasciculata did not show any alteration. The influence on the activity of the cells in the adrenal medulla is supposed to be due to a depression in the central nervous system by Inactin. The slight activation of the zona glomerulosa is attributed to stimulation of the renin-angiotensine-system by an Inactin induced change in renal function. A failing dose dependent effect is taken as a sign of compatibility of the administered drug.
D000311:Adrenal Glands / Q000187:drug effects* / Q000473:pathology; D000758:Anesthesia; D000804:Angiotensin II; D000818:Animals; D007620:Karyometry; D008297:Male; D051381:Rats; D012083:Renin; D013858:Thiobarbiturates / Q000494:pharmacology*
D013858:Thiobarbiturates; D000804:Angiotensin II; D012083:Renin
Zur Frage morphokinetischer Reaktionen in der Nebenniere der Albinoratte nach Narkose mit Inactin