Association of congenital heart defects with season and population density.
Infants born in New England with congenital heart defects were examined for association with time of year or population density. Moderate seasonal peaks in births were noted for complex ventricular septal defect, malposition defects, and transposition of the great arteries. Positive associations with population density were found for pulmonary atresia with ventricular septal defect, ventricular septal defect with secondary anomalies, and tricuspid atresia.
D000328:Adult; D005260:Female; D006330:Heart Defects, Congenital / Q000453:epidemiology*; D006345:Heart Septal Defects, Ventricular / Q000453:epidemiology; D006351:Heart Valves / Q000002:abnormalities; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008423:Maternal Age; D009511:New England; D011156:Population Density; D012621:Seasons; D013997:Time Factors