title: A large pericentric inversion of human chromosome 8.
abstract: A large pericentric inversion, inv(8) (p11q24), was ascertained in a male investigated because his wife had had repeated miscarriages. The inversion segregated in 3 generations of the family, and no chromosomally unbalanced offspring were detected. The miscarriage and the inversion could not be causally related.
mesh_terms: D000022:Abortion, Spontaneous / Q000235:genetics*; D000328:Adult; D002869:Chromosome Aberrations; D007446:Chromosome Inversion; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D010375:Pedigree; D011247:Pregnancy