title: A simplified method for measuring fetal hemoglobin.
abstract: Despite confirmation of the placental location by ultrasound examination, bloody tap during diagnostic and therapeutic amniocentesis may occur. If the blood originates from the fetus, such unfavorable complications as fetomaternal transfusion or maternal sensitization may result. Thus, it is necessary to determine immediatley the origin of the blood by the presence of fetal hemoglobin (HbF) in the specimen. To meet an urgent demand for a simpler and faster method for measuring HbF within a few minutes at bedside without requiring complicated procedures or instrumentation, a method has been developed which uses the alkali denaturation technic.
mesh_terms: D000649:Amniocentesis; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D006452:Hemoglobinometry / Q000379:methods*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D011247:Pregnancy
chemical_list: D006454:Hemoglobins