[Skin vasoconstriction effect of contact antiphlogistics].
Five contact antiphlogistics were evaluated and compared to hydrocortisone by the human skin vasoconstriction assay in 20 volunteers. The test concentrations ranged from 10(-2) to 10(-6) w/w; the duration of occlusive application was 16 h. The substances could be ranked as follows in ascending order of activity (index values in relation to hydrocortisone).
D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001241:Aspirin / Q000494:pharmacology; D002019:Bufexamac / Q000494:pharmacology; D006801:Humans; D006854:Hydrocortisone / Q000494:pharmacology; D007213:Indomethacin / Q000494:pharmacology; D010113:Oxyphenbutazone / Q000494:pharmacology; D012459:Salicylates / Q000494:pharmacology; D012867:Skin / Q000098:blood supply* / Q000187:drug effects; D014661:Vasoconstriction / Q000187:drug effects*
D000893:Anti-Inflammatory Agents; D012459:Salicylates; D002019:Bufexamac; D010113:Oxyphenbutazone; D001241:Aspirin; D006854:Hydrocortisone; D007213:Indomethacin
Hautvasokonstriktionseffekt von Kontaktantiphlogistika.