title: Adrenergic compounds and the respiratory tract. A physiological and electron-microscopical study.
abstract: Studies were undertaken to determine the effect of several adrenergic compounds on ciliary activity and on the micromorphology of the goblet cells and mucous glands. All the substances tested, L-adrenaline, d-L-ephedrine, N-isopropyl-noradrenaline and 1-(4-amino-3, 5-dichlorphenyl)-2-tert-butyl-aminoethanol-HCl increased ciliary activity, but have markedly different effects on goblet cells, mucous glands and on the quality of the produced mucus.
mesh_terms: D000818:Animals; D001980:Bronchi / Q000187:drug effects* / Q000648:ultrastructure; D002415:Cats; D002923:Cilia / Q000187:drug effects* / Q000502:physiology; D004809:Ephedrine / Q000494:pharmacology; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D008297:Male; D009093:Mucus / Q000187:drug effects* / Q000378:metabolism; D009638:Norepinephrine / Q000031:analogs & derivatives / Q000494:pharmacology; D051381:Rats; D013566:Sympathomimetics / Q000494:pharmacology*; D014132:Trachea / Q000187:drug effects* / Q000648:ultrastructure
chemical_list: D013566:Sympathomimetics; D004809:Ephedrine; D009638:Norepinephrine; D004837:Epinephrine