Carbenicillin in the treatment of infections involving anaerobic bacteria.
Twenty-one patients with serious infections involving anaerobic bacteria were treated with carbenicillin. Multiple anaerobes were involved in 8 cases, and in 10 cases, facultative anaerobes were also isolated. Bacteroides fragilis was isolated in 10 cases. Results were judged excellent in 7 cases, good in 8 cases, and fair in 5 cases. These data suggest that carbenicillin may be an effective antibiotic for the therapy of infections due to anaerobic bacteria, particularly those involving B. fragilis.
D000693:Anaerobiosis; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D001442:Bacteroides Infections / Q000188:drug therapy; D001441:Bacteroides fragilis; D002228:Carbenicillin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008826:Microbial Sensitivity Tests
D002228:Carbenicillin