Liposomes in immunology: the immune response against antigen-containing liposomes.
Three ways of antigen administration to rabbits were compared with respect to the resulting immune responses. Antigen was administered free in solution, entrapped in liposomes or free in solution but together with empty liposomes. Liposomal material showed adjuvant activity when injected together with free antigen, but a much stronger adjuvant effect was found when antigen was injected entrapped in liposomes.
D000276:Adjuvants, Immunologic; D000818:Animals; D000917:Antibody Formation; D000941:Antigens / Q000008:administration & dosage*; D005260:Female; D008081:Liposomes / Q000276:immunology*; D008264:Macrophages / Q000276:immunology; D008297:Male; D011817:Rabbits; D012709:Serum Albumin / Q000276:immunology
D000276:Adjuvants, Immunologic; D000941:Antigens; D008081:Liposomes; D012709:Serum Albumin