Somatomedin A in human serum, determined by radioreceptor assay.
Somatomedin A was determined by radioreceptor assay in serum from patients with various disorders. The mean values of somatomedin A in serum from 20 adult subjects, 21 patients with acromegaly, and 17 patients with hypopituitary dwarfism were 1.08 +/- 0.08, 3.02 +/- 0.33 and 0.44 +/- 0.03 U/ml, respectively. In children below 2 years of age, low levels were found (mean 0.40 +/- 0.04 U/ml). Normal levels were found in patients with Turner's syndrome and primary hypothyroidism, increased levels in uraemic patients, and decreased levels in Laron dwarfs.
D000172:Acromegaly / Q000097:blood*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004393:Dwarfism, Pituitary / Q000097:blood*; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000097:blood*; D007223:Infant; D008297:Male; D008875:Middle Aged; D011869:Radioligand Assay; D013002:Somatomedins / Q000097:blood*; D014424:Turner Syndrome / Q000097:blood*; D014511:Uremia / Q000097:blood*
D013002:Somatomedins