Preparation and evaluation of 111In-labeled leukocytes as an abscess imaging agent in dogs.
Leukocytes labeled with 111In chelated with 8-hydroxyquinoline were evaluated as an abscess imaging agent in dogs. The labeling technique is simple and offers 75-95% efficiency. The half-clearance time of the labeled leukocytes is 6-10 hours, and the target-to-blood activity ratios are higher than those of other compounds now in use. The authors suggest that 111In-labeled leukocytes replace 67Ga citrate as a routine abscess imaging agent.
D000038:Abscess / Q000175:diagnosis*; D000818:Animals; D004285:Dogs; D007204:Indium; D007962:Leukocytes; D011868:Radioisotopes; D011877:Radionuclide Imaging / Q000379:methods*
D011868:Radioisotopes; D007204:Indium