[A comparative study of serum H-antibodies in typhoid patients and bacteria carriers].
A study was made of the dynamics of serum H-antibodies in typhoid patients depending on the period of the disease and the severity of its course; the blood sera of chronic carriers were examined as well. H-antibodies were determined in the indirect hemagglutination test with the use of erythrocyte H-dignoasticum. Antibodies of different physico-chemical nature (of IgG and IgM classes) were obtained by fractionation in columns with DEAE-cellulose. Results of the investigations showed that the titres of sum total serum H-antibodies failed to depend on the severity of the course of the disease. The maximum value of the mean geometrical titre of H-antibodies in the blood serum was determined on the 3rd-4th week from the onset of the disease. In chronic carriers the sum total H-antibody titres were greater than in typhoid patients. The serum H-antibody titres increased on account of IgG-globulins both in the typhoid patients and in carriers.
D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial; D002353:Carrier State / Q000276:immunology*; D005260:Female; D005407:Flagella / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008297:Male; D008875:Middle Aged; D014435:Typhoid Fever / Q000276:immunology*
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Sravnitel'noe izuchenie syvorotochnykh H-antitel u bol'nykh briushnym tifom i bakterionositeleĭ