title: Pathogenesis of solar urticaria. Sweat droplet in testing for photosensitivity.
abstract: It was impossible to replicate solar urticaria lesions by irradiation in the laboratory, until the role of sweating was recognized. We found that the sweat droplet, acting as a lens, serves as a photointensifier. As such, sweat would appear to play a meaningful role in the pathogenesis of cutaneous photosensitivity reactions, as well as be an adjuvant in phototesting.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D010787:Photosensitivity Disorders / Q000150:complications*; D013472:Sunlight; D013542:Sweat; D014581:Urticaria / Q000209:etiology*