Effects of hypo- and hyperthyroidism on the activity of cystathionase in mammalian parenchymatous organs during early development.
In rats after neonatal thyroid destriction, cystathionae in liver and pancreas increased, but the enzyme activity in kidneys decreased. Substitution with thyroxine corrected these changes. Excess of thyroxine, too, had an effect on tissue cystathionase.
D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism*; D003542:Cystathionine gamma-Lyase / Q000378:metabolism*; D007037:Hypothyroidism / Q000201:enzymology*; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008190:Lyases / Q000378:metabolism*; D010179:Pancreas / Q000201:enzymology; D051381:Rats; D013965:Thyroidectomy; D013974:Thyroxine / Q000494:pharmacology*
D008190:Lyases; D003542:Cystathionine gamma-Lyase; D013974:Thyroxine