title: Nucleus suprachiasmaticus: the biological clock in the hamster?
abstract: Destruction of the suprachiasmatic nuclei in the golden hamster by bilateral radiofrequency lesions abolishes three well-documented circadian rhythms--locomotor activity, estrous cyclicity, and photoperiodic photosensitivity. Entrainment of these rhythms by light cycles fails in lesioned hamsters; females become persistently estrous; in both sexes locomotor activity becomes sporadic, confined primarily to the light instead of darkness, and is totally arrhythmic when lesioned animals are exposed to continuous darkness; the photoperiodic gonadal response (gonadal regression induced by short day lengths) is abolished; lesioned animals remain reproductively mature irrespective of photoperiodic treatment.
mesh_terms: D000818:Animals; D001683:Biological Clocks; D006224:Cricetinae; D004971:Estrus; D005260:Female; D007031:Hypothalamus / Q000502:physiology*; D008027:Light; D008297:Male; D009043:Motor Activity / Q000502:physiology; D010507:Periodicity; D011247:Pregnancy; D013495:Supraoptic Nucleus / Q000502:physiology*