title: [Scanning electron-microscopic findings in orthoergically damaged skin surfaces of hairless mice (author's transl)].
abstract: Mechanic-chemically defined irritation of the skin surface of hairless mice regularly leads to macroscopically sub-visible changes of the horny layer. Scanning electron-microscopic analysis reveals extended regular horny layer dehiscences, as well as deeper dehiscence or trench formations in the area of irritation, as compared to normal skin. The damaged horny layer sample, presented respectively, depends-to a degree-upon type, intensity and duration of irritation. Hairless mice proved to be best suited at test animals for informative studies concerning cutaneous resistance to stress.
mesh_terms: D000818:Animals; D003877:Dermatitis, Contact; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D007509:Irritants; D008297:Male; D051379:Mice; D008819:Mice, Nude; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D012867:Skin / Q000293:injuries* / Q000648:ultrastructure; D013314:Stress, Mechanical; D014947:Wounds and Injuries / Q000473:pathology
chemical_list: D007509:Irritants
vernacular_title: Rasterelektronenmikroskopische Befunde an der orthoergisch geschädigten Hautoberfläche haarloser Mäuse