Sympathetic innervation of the carotid bifurcation in the rabbit and cat: blood vessels, carotid body and carotid sinus. A fluorescence and electron microscopic study.
Two postganglionic branches of the superior cervical ganglion enter the area of the carotid bifurcation in the rabbit and the cat. The common and external carotid arteries receive a rich adrenergic nerve supply, which can be demonstrated by fluorophores of biogenic amines appearing after formaldehyde treatment. The internal carotid artery is only sparsely innervated; however, it shows a dense sympathetic supply at the site of pressor receptors. Following removal of the superior cervical ganglion, a total loss of fluorescent adrenergic nerves occurs and degeneration of nerve endings possessing dense core vesicles is conspicuous. These nerve terminals are situated mainly subendothelially in the carotid body sinusoids; they only rarely terminate on type I cells.
D000818:Animals; D002339:Carotid Arteries / Q000294:innervation*; D002342:Carotid Artery, External / Q000294:innervation; D002343:Carotid Artery, Internal / Q000294:innervation; D002344:Carotid Body; D002346:Carotid Sinus / Q000294:innervation*; D002415:Cats / Q000033:anatomy & histology*; D005727:Ganglia, Spinal; D009411:Nerve Endings; D011311:Pressoreceptors; D011817:Rabbits / Q000033:anatomy & histology*