title: Changes in rate of methemoglobin reduction and oxygen affinity of erythrocytes incubated with inosine, pyruvate and phosphate.
abstract: Incubation of human erythrocytes with inosine, pyruvate and phosphate increases several fold the ferrihemoglobin reductase activity, the values of which, however, depend on the age of blood (by 6 to 2 times with respect to the normal value of fresh blood).
mesh_terms: D042966:Cytochrome-B(5) Reductase / Q000378:metabolism*; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D007288:Inosine / Q000494:pharmacology; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism*; D009996:Osmotic Fragility / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects; D010710:Phosphates / Q000494:pharmacology; D011773:Pyruvates / Q000494:pharmacology
chemical_list: D010710:Phosphates; D011773:Pyruvates; D007288:Inosine; D009247:NADH, NADPH Oxidoreductases; D042966:Cytochrome-B(5) Reductase