Radiation-induced cerebrovascular disease in children.
Radiation-induced internal carotid artery occlusion has not been well recognized previously as a cause of childhood cerebrovascular disease. A child who had received radiation as a neonate for a hemangioma involving the left orbit at the age of 6 years experienced a recurrent right-sided paresis, vascular headaches, and speech difficulties. Angiography showed a hypoplastic left carotid artery with occlusion of both the anterior and middle cerebral arteries. Collateral vessels bypassed the occluded-stenotic segments. Review of the literature showed two additional cases of large vessel occlusion in childhood associated with anastomatic telangiectatic vessel developmental following early radiation therapy of facial hemangioma.
D000367:Age Factors; D002561:Cerebrovascular Disorders / Q000209:etiology* / Q000503:physiopathology; D002648:Child; D003097:Collateral Circulation; D005153:Facial Neoplasms / Q000532:radiotherapy; D005260:Female; D006391:Hemangioma / Q000532:radiotherapy; D006801:Humans; D011832:Radiation Injuries