The occurrence and identification of o-hydroxyhippuric acid (salicyluric acid) in the urine of sick children.
O-Hydroxyhippuric acid has been identified in the urine of a number of sick children who were not receiving salicylate-containing drugs. Characterisation was effected by thin-layer and gas-liquid chromatography and by gas-liquid chromatography-mass spectrometry. An association between gastro-intestinal dysfunction and the excretion of o-hydroxyhippuric acid was observed in approximately 50% of the patients who excreted this substance.
D002648:Child; D002849:Chromatography, Gas / Q000379:methods; D002855:Chromatography, Thin Layer / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D005767:Gastrointestinal Diseases / Q000652:urine*; D006626:Hippurates / Q000652:urine*; D006801:Humans
D006626:Hippurates; C000693:salicylurate