Plasma dopamine beta-hydroxylase in a noradrenalin-secreting pheochromocytoma.
Circulating dopamine beta-hydroxylase activity was studied in a case of a hypertensive patient bearing a pheochromocytoma. The tumour secreted noradrenalin. The enzyme activity was found to decrease gradually after removal of the tumour, and to reach a stable value, in correlation with the decrease of urinary catecholamines. It is concluded that some pheochromocytoma tumours are able to secrete dopamine beta-hydroxylase.
D000328:Adult; D004299:Dopamine beta-Hydroxylase / Q000097:blood*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism*; D010673:Pheochromocytoma / Q000150:complications / Q000378:metabolism* / Q000601:surgery
D004299:Dopamine beta-Hydroxylase; D009638:Norepinephrine