Influence of granulation liquid flow rate on particle-size distribution in spray-granulate products.
Granulations were made at various air speeds and various rates of addition of granulating liquid in a spray-granulatin assembly. The ensuring particle sizes were log-normal, and the data substantiate that the process is of the nature previously described. The mean diameter obtained was approximately proportional to the liquid flow rate squared but was independent of air rate. The standard deviation was independent of both parameters.
D004339:Drug Compounding; D006244:Hardness; D008962:Models, Theoretical; D010316:Particle Size; D011208:Powders; D011312:Pressure; D013607:Tablets; D013696:Temperature; D013997:Time Factors
D011208:Powders; D013607:Tablets