title: [Clinical and experimental status of the metabolic aspects of obstructive jaundice].
abstract: In the paper, the authors gave an analysis of some aspects of the metabolism in 90 patients, treated surgically for extrahepatic bile tract diseases (in 43 of them obstructive jaundice being noted), and the results of 34 experiments on white rats are summarized. Based on the conducted studies on acid-base balance, electrolyte metabolism and oxidative phosphorylation in hepatic mitochondria in the experiment under various kinds of anesthesia, some recommendations are given for including sodium oxybutyrate in anesthesia, the latter possessing a positive metabolic effect in patients with obstructive jaundice.
mesh_terms: D000136:Acid-Base Equilibrium / Q000187:drug effects; D000328:Adult; D000818:Animals; D001663:Bilirubin / Q000097:blood; D002779:Cholestasis / Q000378:metabolism* / Q000601:surgery; D004986:Ether; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism; D009458:Neuroleptanalgesia; D051381:Rats; D012978:Sodium Oxybate; D013997:Time Factors
chemical_list: D004986:Ether; D012978:Sodium Oxybate; D001663:Bilirubin
vernacular_title: O sostoianii nekotorykh storon metabolizma pri obturatsionnoĭ zheltukhe v klinike i éksperimente.