Hormone implants for urinary disorders in postmenopausal women.
Urinary disorders associated with the menopause were studied in 300 postmenopausal women between the ages of 45 and 85; 210 were multiparous and 90 nulliparous. The presenting urinary symptom was dysuria in 60 patients and incontinence in 100 patients. In the latter group, 25 had urgency-incontinence, 45 stress-incontinence, and 30 a combined form. The distal part of the urethra, being of the same embryologic origin as the genital tract, is estrogen-dependent. Hormone replacement in the form of implants resulted in improvement in 70 percent of the patients and thus reduced the need for surgical intervention.
D000368:Aged; D004958:Estradiol / Q000627:therapeutic use; D004967:Estrogens / Q000502:physiology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008593:Menopause; D008875:Middle Aged; D011374:Progesterone / Q000627:therapeutic use; D013739:Testosterone / Q000627:therapeutic use; D014521:Urethra / Q000502:physiology; D014549:Urinary Incontinence / Q000188:drug therapy*; D014550:Urinary Incontinence, Stress / Q000188:drug therapy; D014555:Urination Disorders / Q000188:drug therapy*
D004967:Estrogens; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol