title: [Method of quantitative evaluation of the reactivity of the microvessels to vasoactive substances in patients with hypertensive disease].
abstract: A method developed by the authors is described that consists in a quantitative test for the evaluation of the reactivity of the microvessels judging by the degree of changes in the resorption speed of isotopes from a tissue depot. In patients with essential hypertension an increased vascular reactivity was revealed with reference to angiotensin, noradrenalin and serotonin, as well as an increased duration of the effect of angiotensin. The highest vascular reactivity was noted in patients with stage II hypertension who have retained a hyperkinetic type of circulation.
mesh_terms: D000804:Angiotensin II / Q000494:pharmacology*; D002196:Capillaries / Q000503:physiopathology*; D002199:Capillary Permeability / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008722:Methods; D009638:Norepinephrine / Q000494:pharmacology; D012701:Serotonin / Q000494:pharmacology*; D012867:Skin / Q000098:blood supply; D012979:Sodium Radioisotopes
chemical_list: D012979:Sodium Radioisotopes; D000804:Angiotensin II; D012701:Serotonin; D009638:Norepinephrine
vernacular_title: Metod kolichestvennoĭ otsenki reaktivnosti mikrososudov po otnosheniiu k vazoaktivnym veshchestvam u bol'nykh gipertonicheskoĭ bolezn'iu