title: The relative biological effectiveness (RBE) and oxygen enhancement ratio (OER) of neon ions for the EMT6 tumor system.
abstract: EMT6 tumors were exposed to neon ions in vivo and in vitro in the plateau and spread-out Bragg peak regions of the beam. The RBE in vivo was 1.7-2.1 in the plateau region and 2.6-2.9 in the Bragg peak; the OER was 2.0 and 1.4, respectively. Neon ions have great potential in the radiotherapy of tumors because of their decreased OER and excellent depth-dose distribution in tissue.
mesh_terms: D000818:Animals; D002588:Cesium Radioisotopes / Q000627:therapeutic use*; D004307:Dose-Response Relationship, Radiation; D008325:Mammary Neoplasms, Experimental / Q000532:radiotherapy*; D051379:Mice; D009356:Neon / Q000627:therapeutic use*; D010100:Oxygen; D011879:Radiotherapy Dosage
chemical_list: D002588:Cesium Radioisotopes; D009356:Neon; D010100:Oxygen