title: [Clinical manifestations of disseminated sclerosis in childhood].
abstract: The author studied children from 6-14 years with disseminated sclerosis in the area of a  decreased risk to this disease. The early period of the disease in this age group was very difficult to discern. As a rule, disseminated sclerosis in children in detected by a retrospective analysis of the clinical development. In children, as in adults, the clinical course has a remittent development, where there are remissions and exacerbations. More frequently than in adults, the disease acquires a hyperkinetic form, which is considered to be most malignant. Probably the disease occurs not at 12-15 years, as it is being pointed in the literature but much earlier (4-5 years). Exacerbations of disseminated sclerosis in children, unlike exacerbations in adults occur not so much from the influence of cold factors as from warm. In order to avoid a hyperdiagnosis of disseminated sclerosis in children a differential diagnosis should be made between hereditary-degenerative disorders of the nervous system and progressive forms of panencephalitis.
mesh_terms: D000293:Adolescent; D002490:Central Nervous System / Q000503:physiopathology; D002648:Child; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000503:physiopathology; D009461:Neurologic Manifestations; D012075:Remission, Spontaneous
vernacular_title: O klinicheskikh proiavleniiakh rasseiannogo skleroza v detskom vosraste.