title: Unrelenting hypotension associated with an acute abdomen in a comatose hemophiliac child: a case report.
abstract: A comatose 4-year-old hemophiliac presented with an acute abdomen; subsequently he developed unrelenting hypotension. An immediate exploratory laparotomy was required, without time for determining baseline factor VIII (AHF) levels. Despite hypotension and hemorrhage, vigorous intraoperative fluid volume replacement and the administration of fresh frozen plasma and AHF concentrates brought a successful conclusion.
mesh_terms: D000006:Abdomen, Acute / Q000601:surgery*; D002675:Child, Preschool; D003128:Coma / Q000150:complications*; D004630:Emergencies; D005169:Factor VIII / Q000627:therapeutic use; D006467:Hemophilia A / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007022:Hypotension / Q000209:etiology*; D007427:Intracranial Pressure; D008297:Male
chemical_list: D005169:Factor VIII