Evaluation of selected compounds for estrus control in the bitch.
Steroidal and nonsteroidal compounds were evaluated for estrus inhibition in the bitch. Mibolerone, an anabolic steroid, was effective and appeared to be safe. The remaining compounds lacked efficacy or had extensive side effects, or both.
D000818:Animals; D002987:Clitoris / Q000187:drug effects; D004283:Dog Diseases / Q000139:chemically induced; D004285:Dogs / Q000502:physiology*; D004714:Endometrial Hyperplasia / Q000662:veterinary; D004716:Endometritis / Q000662:veterinary; D004963:Estrenes / Q000009:adverse effects / Q000494:pharmacology; D004971:Estrus / Q000187:drug effects*; D005260:Female; D007964:Leukocytosis / Q000662:veterinary; D009256:Nafoxidine / Q000009:adverse effects / Q000494:pharmacology; D011247:Pregnancy; D014621:Vagina / Q000187:drug effects
D004963:Estrenes; D009256:Nafoxidine