Changes in rate of methemoglobin reduction and oxygen affinity of erythrocytes incubated with inosine, pyruvate and phosphate.
Incubation of human erythrocytes with inosine, pyruvate and phosphate increases several fold the ferrihemoglobin reductase activity, the values of which, however, depend on the age of blood (by 6 to 2 times with respect to the normal value of fresh blood).
D042966:Cytochrome-B(5) Reductase / Q000378:metabolism*; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D007288:Inosine / Q000494:pharmacology; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism*; D009996:Osmotic Fragility / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects; D010710:Phosphates / Q000494:pharmacology; D011773:Pyruvates / Q000494:pharmacology
D010710:Phosphates; D011773:Pyruvates; D007288:Inosine; D009247:NADH, NADPH Oxidoreductases; D042966:Cytochrome-B(5) Reductase