title: Detergent enema: a cause of caustic colitis.
abstract: A 5-year-old boy developed acute colitis followed by stricture formation as a result of a detergent enema. The acute phase of the caustic induced colitis was reproduced in the dog and the rat using full strength and diluted detergent enemas. The severity of the experimental colitis was shown to be directly related to the concentration of the detergent.
mesh_terms: D000818:Animals; D002675:Child, Preschool; D003092:Colitis / Q000139:chemically induced* / Q000473:pathology; D003106:Colon / Q000187:drug effects / Q000473:pathology; D003902:Detergents / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology; D004285:Dogs; D004733:Enema; D006801:Humans; D008297:Male; D051381:Rats
chemical_list: D003902:Detergents