Meningeal carcinomatosis. Case report and review of the literature.
Untreated meningeal carcinomatosis is a uniformly fatal type of metastatic disease presenting with many protean signs and symptoms. We achieved significant palliation and long-term survival in our patient, using combined chemotherapy and radiotherapy; responses to both intrathecal methotrexate and experimental oral CCNU were observed.
D000328:Adult; D001932:Brain Neoplasms / Q000628:therapy*; D001943:Breast Neoplasms / Q000628:therapy*; D002277:Carcinoma / Q000628:therapy*; D005260:Female; D006801:Humans; D008130:Lomustine / Q000627:therapeutic use; D008578:Meninges; D008727:Methotrexate / Q000627:therapeutic use; D009362:Neoplasm Metastasis
D008130:Lomustine; D008727:Methotrexate