Study of inhalation toxicity of performic, peracetic and perpropionic acid in mice.
The acute and subacute inhalation toxicity of laboratory performic, peracetic and stabilized aqueous peracetic acid solution. The differences in the toxicity of the studied of the commercial preparation Persteril for mice was studied. Persteril is a 40% peracids were not statistically significant. The histological findings in the lung tissue of intoxicated mice show that the effet of the given peracids is qualitatively the same. Although their toxicity is not very high, in repared inhalation they can induce temporary pathomorphological lesions in the lung parenchyma and have a negative effect on the development of mice in concentrations of about only 70 mg/m3 air. As regards their inhalation toxicity, performic and perpropionic acid have no advantages over peracetic acid for practical use in the air disinfection. The findings show that it is necessary for persons carrying out spatial disinfection with one of the studied peracids to wear an protective mask.
D000085:Acetates / Q000633:toxicity*; D000336:Aerosols; D000818:Animals; D001996:Bronchopneumonia / Q000139:chemically induced; D005561:Formates / Q000633:toxicity*; D007249:Inflammation; D007928:Lethal Dose 50; D008168:Lung / Q000473:pathology; D051379:Mice; D010463:Peracetic Acid / Q000633:toxicity*; D011422:Propionates / Q000633:toxicity*; D012131:Respiratory Insufficiency / Q000139:chemically induced; D013997:Time Factors
D000085:Acetates; D000336:Aerosols; D005561:Formates; D011422:Propionates; D010463:Peracetic Acid