[Multiple myeloma with monoclonal IgE gammopathy (author's transl)].
In a 48-year-old female patient with monoclonal gammopathy and histologically proven plasmocytoma IgE could be demonstrated in bone marrow plasma cells by means of direct immunofluorescence. Immunoelectrophoresis showed a light-chain type chi. Radiographically diffuse osteolytic skeletal lesions were found. Bence-Jones proteinuria and plasma cell leukaemia were absent. This patient represents the fourth recognized case of IgE myeloma. The chi/lambda ratio in IgE myeloma is 1:1 according to present knowledge.
D001853:Bone Marrow / Q000276:immunology; D001854:Bone Marrow Cells; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007122:Immunoelectrophoresis; D007073:Immunoglobulin E / Q000032:analysis; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications*; D010950:Plasma Cells / Q000276:immunology
D007073:Immunoglobulin E
Multiples Myelom mit monoklonaler IgE-Gammopathie