title: Acclimization in a hot, humid environment: cardiovascular adjustments.
abstract: Four trained young men worked for 4 h/day at 40-50% of their maximum aerobic capacity first  for 3 days at 25 degrees C db, 18 degrees C wb, and then for 10 consecutive days at 45 degrees C db, 32 degrees C wb. This portion of the study was mainly concerned with central circulatory changes during acclimatization. The central circulatory adaptation to work in heat could be divided into four distinct phases: phase I (day 1) was characterized by a progressive fall in stroke volume (SV) during heat exposure but cardiac output (CO) was maintained above control values by high heart rates. Phase II (days 2 and 3) was marked by increases in SV ande decreases in heart rate but with little change in CO from phase I. During phase III (days 4-8 of acclimatization), CO increased due to increases in SV. Phase IV (days 6-8) was associated with decreases in rectal and skin temperature towards control levels. SV and HR both decline in this phase so that CO was not elevated greatly above  control levels. The results indicated that central circulatory and temperature regulating events are not casually associated in acclimatization.
mesh_terms: D000064:Acclimatization; D001831:Body Temperature; D001833:Body Temperature Regulation; D002302:Cardiac Output; D006339:Heart Rate; D006439:Hemodynamics; D006358:Hot Temperature; D006801:Humans; D006813:Humidity; D008297:Male; D010101:Oxygen Consumption; D005082:Physical Exertion; D014937:Work