title: Familial methaemoglobinaemia and haemolytic anaemia in the horse associated with decreased erythrocytic glutathione reductase and glutathione.
abstract: A trotter mare with a history of poor performance was found to have methaemoglobinaemia and haemolytic anaemia associated with decreased erythrocyte glutathione reductase and glutathione levels. The mare's dam, which also had a history of poor performance, was subsequently found to be similarly affected.
mesh_terms: D000743:Anemia, Hemolytic / Q000235:genetics; D000745:Anemia, Hemolytic, Congenital / Q000097:blood / Q000662:veterinary*; D000818:Animals; D004912:Erythrocytes / Q000032:analysis* / Q000201:enzymology; D005260:Female; D005978:Glutathione / Q000097:blood*; D005980:Glutathione Reductase / Q000097:blood*; D006734:Horse Diseases / Q000097:blood / Q000235:genetics*; D006736:Horses; D008708:Methemoglobinemia / Q000097:blood / Q000235:genetics / Q000662:veterinary*
chemical_list: D005980:Glutathione Reductase; D005978:Glutathione