[The role of catecholamines, acetylcholine and cholinesterase activity in the development of the cataleptic action of triftazin following repeated administration].
Catalepsy occurring in rats in a singular and repeated introduction of triftasine has a manifold mechanism, the main components of which are related to the metabolism of dophamine, acetylcholine and cholinesterase activity. A change in the intensity of catalepsy in a multiple introduction of the preparation is due mainly to cholinergic influences.
D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D002375:Catalepsy / Q000139:chemically induced*; D002421:Caudate Nucleus / Q000201:enzymology / Q000378:metabolism*; D002802:Cholinesterases / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism; D004837:Epinephrine / Q000378:metabolism; D005625:Frontal Lobe / Q000201:enzymology / Q000378:metabolism*; D006801:Humans; D008297:Male; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D014268:Trifluoperazine
D014268:Trifluoperazine; D002802:Cholinesterases; D000109:Acetylcholine; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine
Rol' katekholaminov, atsetilkholina i aktivnosti kholinésterazy v razvitii katalepticheskogo deĭstviia triftazina pri ego mnogokratnom vvedenii