Interaction between asymmetric solutes and solvents. Diamides derived from L-valine as stationary phases in gas-liquid partition chromatography.
The resolution of enantiomers of (+/-)-a-amino acid derivatives on optically active diamides derived from L-valine, R1CONHCH[CH(CH3)2]CONHR2, as gas chromatographic stationary phases was studied. The effects of the structure of R1 and R2 in the stationary phases, the structure of the racemic a-amino acid derivatives, temperature, etc., on the separation factors are reported. In the light of these and related results, a more probable mechanism of resolution is presented.
D000577:Amides / Q000032:analysis*; D000595:Amino Acid Sequence; D055598:Chemical Phenomena; D002621:Chemistry; D002849:Chromatography, Gas; D002853:Chromatography, Liquid; D004151:Dipeptides / Q000032:analysis*; D004952:Esters / Q000032:analysis; D009904:Optical Rotation; D012995:Solubility; D012997:Solvents; D013237:Stereoisomerism; D014633:Valine / Q000032:analysis*
D000577:Amides; D004151:Dipeptides; D004952:Esters; D012997:Solvents; D014633:Valine