Electrolytic O-demethylation of methoxycatecholamines.
Electrolysis of 3-methoxycatecholamines in physiological solutions resulted in the formation of the parent catecholamines and their oxidation products. Conversion occurred at the anode. Maximal catecholamine production occurred in the presence of ascorbic acid.
D000818:Animals; D001158:Arteries / Q000187:drug effects; D001205:Ascorbic Acid; D003250:Constriction; D004431:Ear, External / Q000098:blood supply; D004572:Electrolysis; D004837:Epinephrine / Q000031:analogs & derivatives / Q000032:analysis / Q000494:pharmacology; D005470:Fluorometry; D008676:Metanephrine / Q000494:pharmacology; D008745:Methylation; D009638:Norepinephrine / Q000032:analysis; D009647:Normetanephrine; D011817:Rabbits; D013864:Thioglycolates
D013864:Thioglycolates; D009647:Normetanephrine; D008676:Metanephrine; D001205:Ascorbic Acid; D009638:Norepinephrine; D004837:Epinephrine