Benign cervical and vaginal changes associated with exposure to stilbestrol in utero.
Examinations of 320 young women allegedly exposed to stilbestrol in utero have revealed at least 12 unique and benign variations from normal anatomy, five in the cervix and seven in the vagina. Over two thirds of the patients revealed one or more of these variations. Some have been previously reported, others have not. None changed significantly or deleteriously during observation. All are described and a representative drawing of each is included. A classificational nomenclature is offered. It is felt that familiarity with these changes will allow presumptive identification by simple pelvic examination of at least two thirds of females exposed to stilbestrol in utero.
D000293:Adolescent; D000328:Adult; D003560:Cysts / Q000139:chemically induced; D004054:Diethylstilbestrol / Q000009:adverse effects*; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D008431:Maternal-Fetal Exchange; D009092:Mucous Membrane / Q000187:drug effects; D011127:Polyps / Q000139:chemically induced; D011247:Pregnancy; D002577:Uterine Cervical Diseases / Q000139:chemically induced*; D002583:Uterine Cervical Neoplasms / Q000139:chemically induced; D014623:Vaginal Diseases / Q000139:chemically induced*
D004054:Diethylstilbestrol