Aspergillus oryzae meningitis.
In a patient with only meningitis, a septate hypha was seen in a Langhans giant cell, and the rarely pathogenic Aspergillus oryzae was cultured from the cerebrospinal fluid. Serologic results confirmed the diagnosis. The patient responded to therapy with amphotericin B and flucytosine.
D000328:Adult; D000666:Amphotericin B / Q000494:pharmacology; D000908:Antibodies, Fungal / Q000032:analysis; D001230:Aspergillus / Q000302:isolation & purification*; D001236:Aspergillus oryzae / Q000187:drug effects / Q000276:immunology / Q000302:isolation & purification*; D002555:Cerebrospinal Fluid / Q000382:microbiology; D005260:Female; D005437:Flucytosine / Q000494:pharmacology; D006801:Humans; D008581:Meningitis / Q000382:microbiology*
D000908:Antibodies, Fungal; D000666:Amphotericin B; D005437:Flucytosine