title: The release of prostaglandin F2alpha as reflected by 15-keto-13,14-dihydroprostaglandin F2alpha in the peripheral circulation during normal luteolysis in heifers.
abstract: Progesterone and the main plasma metabolite of PGF2alpha, 15-keto-13, 14-dihydro-PGF2alpha, were determined at hourly intervals in the peripheral circulation during luteolysis in two heifers. The prostaglandin release was found to occur during 2-3 days as rapid pulses with a duration of 1-5 hours prior to and during luteolysis, which was indicated by decreasing levels of progesterone.
mesh_terms: D000818:Animals; D001667:Binding, Competitive; D002417:Cattle / Q000502:physiology*; D003338:Corpus Luteum / Q000502:physiology*; D004971:Estrus; D005260:Female; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D011460:Prostaglandins F / Q000378:metabolism*; D011863:Radioimmunoassay
chemical_list: D011460:Prostaglandins F; D011374:Progesterone