Urea and hearing in patients with menière's disease.
Transient hearing improvement was recorded in around 60% of patients with Menière's disease 2 hours after the ingestion of 20 g of urea perorally. Urea slightly increased the serum osmolality, which is thought to cause a transient reduction of the endolymphatic hydrops. Urea has no inconvenient side effects and is recommended primarily as a test substance for the verification of endolymphatic hydrops, in conformity with glycerol.
D000284:Administration, Oral; D006309:Hearing; D006801:Humans; D007761:Labyrinthine Fluids; D008575:Meniere Disease / Q000097:blood / Q000188:drug therapy*; D014508:Urea / Q000008:administration & dosage / Q000627:therapeutic use*
D014508:Urea