title: The prognostic significance of the viscerocardiac reflex phenomenon.
abstract: The acid perfusion test, combined with manometric studies of the oesophagus and serial electrocardiography, has been utilised to determine the incidence of ischaemic ST-segment depression and of significant arrhythmias during acid-induced oesophageal pain. Eight per cent of patients with oesophagitis and coexistent ischaemic heart disease manifest significant ECG changes during oesophageal acid perfusion. The follow-up period of 5 years indicates that these patients have a high incidence of recurrent myocardial infarction.
mesh_terms: D000143:Acids; D000328:Adult; D000787:Angina Pectoris / Q000150:complications; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D003327:Coronary Disease / Q000175:diagnosis*; D004562:Electrocardiography; D004941:Esophagitis / Q000150:complications*; D004947:Esophagus; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D011379:Prognosis; D012008:Recurrence; D012018:Reflex
chemical_list: D000143:Acids