Induction of abortion with 15(S)-15-methyl PGF2alpha (Tham) vaginal suppositories.
The repeated administration of vaginal suppositories containing 1 mg 15(S)-15 methyl PGF2alpha (Tham) sucessfully induced abortions in 60 of 62 patients. Among patients who successfully aborted, the mean abortion time was 19.0 hours. The mean abortion time was not related to gestational age or parity. Sixty (96.8 precent) aborted within 48 hours, and 53 (85.5 percent) aborted within 24 hours. Gastrointestinal side effects occurred for 33.9 percent of the patients. Diarrhea was the most frequent side effect. The abortion was complete for 40.3 percent of the patients.
D000028:Abortion, Induced; D000293:Adolescent; D000328:Adult; D000653:Amniotic Fluid; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D010298:Parity; D011460:Prostaglandins F / Q000009:adverse effects; D011461:Prostaglandins F, Synthetic / Q000008:administration & dosage*; D013488:Suppositories; D013997:Time Factors; D014621:Vagina
D011460:Prostaglandins F; D011461:Prostaglandins F, Synthetic; D013488:Suppositories