Studies on the terminal stages of antibody-complement mediated killing of a tumor cell. III. Effect of membrane active agents.
A comparison of the events leading from T to dead cell and E to E ghost and hemoglobin was made. Transformation of T to dead cells was inhibitable by EDTA, NaF, histamine, DMSO, cytochalasin B and 3'5' cAMP. Transformation of E to E ghost and hemoglobin was only inhibited by EDTA.
D000818:Animals; D000936:Antigen-Antibody Complex; D002462:Cell Membrane / Q000276:immunology; D002470:Cell Survival; D003165:Complement System Proteins / Q000378:metabolism*; D003601:Cytotoxicity Tests, Immunologic; D004912:Erythrocytes / Q000276:immunology; D006168:Guinea Pigs; D007111:Immunity, Cellular; D009374:Neoplasms, Experimental / Q000276:immunology*; D012756:Sheep; D013997:Time Factors
D000936:Antigen-Antibody Complex; D003165:Complement System Proteins