title: Diagnostic problems in drug-induced diseases.
abstract: The evaluation of adverse drug reactions (ADR's) in clinical patients is usually a complex and multifactorial problem. A methodology for this evaluation has been derived from the experience with over 3,000 cases. Illustrative cases are presented to demonstrate in detail a variety of means of linking a drug with an ADR. Emphasis is placed on the frequent diagnostic utility of accurate time-related information, in addition to the use of historical, clinical-laboratory and morphologic findings.
mesh_terms: D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D008297:Male