Contaminants in commercial dapsone.
Three contaminants commonly found in commercial dapsone were identified as 2,4'-sulfonylbis(benzeneamine), 4-(phenylsulfonyl)benzeneamine, and 4-(4'-chlorophenylsulfonyl)benzeneamine. The identities were based on the spectral analysis and unambiguous synthesis of each compound. Solvent-free, pure dapsone was prepared by recrystallization from chloroform.
D055598:Chemical Phenomena; D002621:Chemistry; D003460:Crystallization; D003622:Dapsone / Q000032:analysis* / Q000302:isolation & purification; D004340:Drug Contamination
D003622:Dapsone