The influence of the known radioprotective compounds on the metabolism of human red blood cell. Part II. The influence of cysteamine on enzymic systems.
The influence of cysteamine on the metabolic activity of red blood cells has been estimated in vitro. Cysteamine has a marked influence on the activity of mainly aldolase F-1, 6-P and glucose-6-P dehydrogenase in red blood cells in vitro. The anaerobic metabolism of erythrocytes is more active in the presence of lower doses of cysteamine. Higher concentrations of radioprotector stimulate the pentose phosphate shunt.
D000693:Anaerobiosis; D003543:Cysteamine / Q000494:pharmacology*; D004912:Erythrocytes / Q000201:enzymology*; D005634:Fructose-Bisphosphate Aldolase / Q000097:blood; D005954:Glucosephosphate Dehydrogenase / Q000097:blood; D006801:Humans; D066298:In Vitro Techniques; D007770:L-Lactate Dehydrogenase / Q000097:blood
D003543:Cysteamine; D007770:L-Lactate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D005634:Fructose-Bisphosphate Aldolase