title: A method to study short-term memory (STM) in the goldfish.
abstract: Twenty-one common goldfish (13-15.5 cm long) were randomly divided into alcohol (A) and nonalcohol (NA) groups and were trained in an alcohol solution of 400 mg/100 ml or in water, respectively. All alcohol fish were placed in an alcohol solution of 400 mg/100 ml for 3 hr before training in the same alcohol concentration. Fish were trained on a position discrimination task for 2 consecutive days. The door used for training was that opposite to each fish's spontaneous preference. Savings in relearning on Day 2 was taken as a measure of long term memory strength. Only fish which reached criterion on both days were immediately given 10 forced reversal trails in the opposite direction (i.e., a fish trained on right door was forced to choose the left door.) A and NA subjects were then tested after a 5 min (STM) delay, respectively, in a free choice situation for 10 trails (i.e., neither door was blocked). The results suggest that alcohol facilitates the STM of the forced reversal information.
mesh_terms: D000818:Animals; D003530:Cyprinidae; D004193:Discrimination Learning / Q000187:drug effects; D000431:Ethanol / Q000494:pharmacology; D006054:Goldfish; D008570:Memory, Short-Term / Q000187:drug effects; D013997:Time Factors
chemical_list: D000431:Ethanol