[Hydroxyproline concentration in the blood of patients with diabetes mellitus complicated by angiopathies].
The authors used oxyproline indices for the diagnosis of diabetic nephroangiopathies. Patients with diabetes mellitus of various severity (47 in all) were examined. Disturbance of oxyproline metabolism observed in these patients was particularly pronounced in development of nephroangiopathies; this can apparently be attributed to destruction of the basal membrane. The authors believe that it is difficult to assess the collagen metabolism in patients with diabetes mellitus by the urinary oxyproline content, since these patients display a disturbance of the glomerular function of the liver at various stages of the disease.
D000328:Adult; D000368:Aged; D003925:Diabetic Angiopathies / Q000097:blood*; D003928:Diabetic Nephropathies / Q000097:blood*; D005260:Female; D006801:Humans; D006909:Hydroxyproline / Q000097:blood*; D008297:Male; D008875:Middle Aged
D006909:Hydroxyproline
Soderzhanie oksiprolina v krovi bol'nykh sakharnym diabetom, oslozhnennym angiopatiiami