title: Detection of antibodies of the IgM class in sera of patients recently infected with influenza viruses.
abstract: Sucrose density gradient ultracentrifugation can be used to detect specific 19S antibodies of the IgM class in the sera of patients recently infected with influenza A virus, provided steps are taken to remove non-specific inhibitors of haemagglutination. The usefulness of the procedure for the diagnosis of influenza requires further evaluation.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D002499:Centrifugation, Density Gradient / Q000379:methods; D002645:Chickens / Q000276:immunology; D010856:Columbidae / Q000276:immunology; D005260:Female; D006384:Hemagglutination / Q000187:drug effects; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis*; D009980:Influenza A virus / Q000276:immunology*; D007251:Influenza, Human / Q000175:diagnosis / Q000276:immunology*; D008623:Mercaptoethanol / Q000494:pharmacology; D008970:Molecular Weight; D009975:Orthomyxoviridae / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008623:Mercaptoethanol