title: The aetiology of obesity in children. A study of 101 twin pairs.
abstract: The aetiology of obesity in children is studied here with the aid of a material consisting of 40 monozygotic and 61 dizygotic twins. The importance of heredity, early nutrition, and environment during preschool age is analysed. Genetic factors, studied by comparison of intra-pair differences in monozygotic and dizygotic twins, apparently play a decisive role in the origin of obesity. Analysis of the relation between birth weight and later development of subcutaneous fat in different types of twins does not show that intra-uterine nutrition is of aetiological importance. The comparison at age seven of groups of ordinary siblings and twins of different types does not support the idea that the pre-school environment is of importance in aetiology. Such influence seems to act mainly as a modifying factor.
mesh_terms: D001724:Birth Weight; D002648:Child; D004200:Diseases in Twins; D005260:Female; D006801:Humans; D008297:Male; D008431:Maternal-Fetal Exchange; D009765:Obesity / Q000209:etiology* / Q000235:genetics; D011247:Pregnancy; D012885:Skinfold Thickness