Corneal glycogen synthesis. I. Evidence for a gluconeogenic pathway in beef cornea.
Beef eye anterior chambers were perfused with media containing radiolabeled glycogen precursors. Incorporation of 14C from 1-alanine-U-14C into corneal epithelium glycogen suggested the presence of a gluconeogenic pathway in the eye. Failure to isolate radioactive glucose from 1-alanine-U-14C-containing perfusate after passage through the anterior chamber strongly suggests a corneal site for this pathway.
D000409:Alanine / Q000378:metabolism; D000818:Animals; D000867:Anterior Chamber; D003315:Cornea / Q000378:metabolism*; D005943:Gluconeogenesis; D006003:Glycogen / Q000096:biosynthesis*; D066298:In Vitro Techniques; D010477:Perfusion
D006003:Glycogen; D000409:Alanine