title: Alkaloids of Ocotea brachybotra.
abstract: Aporphine, proaporphine and morphinane alkaloids were isolated from the leaves of a Brazilian Lauracea, Ocotea brachybotra (Meiss.) Mez. The known alkaloids were identified through their physico-chemical properties as: (I) (+/-)-glaziovine, (II) dicentrine, (III) ocopodine, (IV) cassynthicine, (V) predicentrine, (VI) leucoxine, (IX) sinacutine and (X) pallidine. The structure of (VI) leucoxine was confirmed by a detailed analysis of the N.M.R. spectra recorded in various conditions. New morphinane alkaloids, (XI) ocobotrine and (XII) 14-espisinomenine, having the unusual B/C-trans configuration were also isolated. Their structures were determined using spectroscopic methods and chemical correlations.
mesh_terms: D000470:Alkaloids / Q000302:isolation & purification*; D001060:Aporphines / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D009019:Morphinans / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000032:analysis*
chemical_list: D000470:Alkaloids; D001060:Aporphines; D009019:Morphinans