[Dynamics of growth hormone secretion in patients with primary hypothyroidism, before and after treatment with thyroideal hormones].
Growth hormone (GH) secretion was studied in a group of alut controls and a series of patients with primary hypothyroidism before and after treatment with thyroid hormones. Intravenous insulin-induced hypoglycemia was the stimulus used (0,1 UI/kg body weight). It is concluded that in primary hypothyroidism, GH secretion is almost absent due to relative inactivity of the somatotropic cells and/or lack of GH-RH. This decreased secretory response becomes rapidly normal after treatment with physiological doses of thyroid hormones.
D000293:Adolescent; D000328:Adult; D004341:Drug Evaluation; D005260:Female; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy / Q000378:metabolism*; D008297:Male; D012636:Secretory Rate; D013961:Thyroid Gland / Q000378:metabolism*; D013963:Thyroid Hormones / Q000627:therapeutic use*
D013963:Thyroid Hormones; D013006:Growth Hormone
Dinámica de secreción de hormona de crecimiento en pacientes con hipotiroidismo primario, antes y después del tratamiento con hormonas tiroideas