[Changes in some blood biochemical indices in chickens poisoned with Thimet and Letaycide].
Experiments were carried out with a total of 25 chickens of the Leghorn breed divided into two test groups and one control group. The test chickens were given daily the phosphorus organic pesticides timet and lebaized at rates of 0.05 mg anen mg per kg. The treated birds were kept under observation in the course of 72 days recording their cholinesterase activity (ChEA), serumglutamatoxal-acetate transaminase (SGOT), serumglutamatpyruvate transaminase (SGPT), and alkaline phosphatase (APh), and blood sugar level. It was found that as early as the third day from the beginning of the experiment ChEA dropped abruptly--by 62.72 per cent following treatment with timet, and by 29.26 per cent when treatment was carried out with lebaizid. SGOT and SGPT rose up to the 36th day by 78.74 and 59.42 per cent as against the controls. The blood sugar level increased by 20.44 per cent following the administration of timet, and by 6.95 per cent following that of lebaizid. APh on the 12th day was by 60.84 per cent higher as compared to the initial level in the case of timet, and by 39.15 per cent in the case of lebaizid. Results showed that the continuous giving of phosphorus organic insecticides (timet and lebaized) at low rates to chickens leads to the drop of ChA and the rise of SGOT, GPT, APh, and blood sugar, these changes being more clearly manifested in chickens that have been offered timet.
D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001769:Blood / Q000187:drug effects*; D001786:Blood Glucose / Q000032:analysis; D002645:Chickens; D002784:Cholesterol / Q000097:blood; D002802:Cholinesterases / Q000097:blood; D004789:Enzyme Activation / Q000187:drug effects; D005284:Fenthion / Q000506:poisoning*; D007306:Insecticides / Q000506:poisoning*; D010702:Phorate / Q000506:poisoning*; D011041:Poisoning / Q000097:blood*; D013997:Time Factors
D001786:Blood Glucose; D007306:Insecticides; D010702:Phorate; D002784:Cholesterol; D005284:Fenthion; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D002802:Cholinesterases; D000469:Alkaline Phosphatase
Promeni na niakoi biochimichni pokazateli v kruvta na kokoshki pri otraviane s timet i lebaĭtsid