[Pulmonary contusion after blunt chest trauma--an experimental model (author's transl)].
A model in the rat for pulmonary contusion after blunt chest trauma is described. It is possible to avoid trauma of the mediastinal organs, liver and spleen; therefore it is possible to produce pulmonary contusion with a good reproducebility. The parameter for the extent of contusion was the lungweight which rose statistically with a specific force of trauma. Simultaneous injection of high doses of prednisolone with the blunt chest trauma inhibits the increase of the lung weight.
D000818:Animals; D003288:Contusions / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D004195:Disease Models, Animal; D008168:Lung / Q000473:pathology; D055370:Lung Injury; D009929:Organ Size / Q000187:drug effects; D011239:Prednisolone / Q000627:therapeutic use; D051381:Rats; D013898:Thoracic Injuries / Q000150:complications*; D014949:Wounds, Nonpenetrating / Q000150:complications*
D011239:Prednisolone
Lungenkontusion nach stumpfem Thoraxtrauma--ein experimentelles Modell.