Incomplete arylamidase in psoriasis scales.
Electrophoretic and immunological studies revealed that normal and pathologically altered epidermis contains an arylamidase with the electrophoretic mobility of an x-globulin. This enzyme seems to be immunologically identical with an arylamidase secreted by the prostate gland. In psoriasis scales the arylamidase migrates with the electrophoretic mobility of a beta-globulin. Presumably, this enzyme contains fewer neuraminic acid groups than the arylamidase of normal epidermis. It may well be that in psoriasis the synthesis of arylamidase is incomplete.
D000626:Aminopeptidases / Q000032:analysis; D003429:Cross Reactions; D006801:Humans; D007122:Immunoelectrophoresis; D011565:Psoriasis / Q000201:enzymology*; D012661:Semen / Q000201:enzymology; D012794:Sialic Acids / Q000032:analysis; D012867:Skin / Q000201:enzymology; D012878:Skin Neoplasms / Q000201:enzymology
D012794:Sialic Acids; D000626:Aminopeptidases