Changes in the frequency of electroencephalographic rhythms of the rat caused by single, intraperitoneal injections of ethanol.
Ethanol (2-4 g/kg, i.p.) caused a slowing of the three main forms of electroencephalographic activity of the waking rat (hippocampal theta rhythm, and hippocampal and neocortical large-irregular amplitude activity). The effect was dose-dependent within those dose ranges, and bore a gross relation to blood ethanol levels. Lower dosages (0.5-1 g/kg) had no effect.
D001831:Body Temperature / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography; D000431:Ethanol / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D007274:Injections, Intraperitoneal; D013997:Time Factors
D000431:Ethanol