Spontaneous hematologic remission in agnogenic myeloid metaplasia.
A 60 year old man had well documented agnogenic myeloid metaplasia with pancytopenia. Frequent red cell transfusions were required for two and a half years. Androgen therapy was not beneficial and was discontinued 26 months before a spontaneous hematologic remission occurred. The remission was documented by bone marrow biopsy and reticuloendothelial scanning of the marrow. Hepatosplenomegaly, poikilocytosis and expansion of the marrow space have persisted despite hematologic remission.
D001853:Bone Marrow / Q000473:pathology; D001856:Bone Marrow Examination; D005474:Fluoxymesterone / Q000627:therapeutic use; D005492:Folic Acid / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D012157:Mononuclear Phagocyte System / Q000473:pathology; D010110:Oxymetholone / Q000627:therapeutic use; D055728:Primary Myelofibrosis / Q000188:drug therapy / Q000473:pathology; D012008:Recurrence; D012075:Remission, Spontaneous
D005492:Folic Acid; D005474:Fluoxymesterone; D010110:Oxymetholone