title: Neonatal pulmonary hypoplasia after prolonged leakage of amniotic fluid.
abstract: The clinical, radiological, and pathological features of the 'oligohydramnios tetrad' (Potter's facies, limb malpositions, pulmonary hypoplasia, and growth retardation) resulting from chronic amniotic fluid leakage are described in 2 infants who died of respiratory failure within 12 hours of delivery. A third infant with a partial form of the syndrome had prolonged respiratory symptoms and survived the neonatal period: the course of the disease and the radiological findings were compatible with a hypothetical diagnosis of partial pulmonary hypoplasia. Pulmonary hypoplasia should be recognized as a cause of chronic respiratory symptoms in viable infants.
mesh_terms: D000015:Abnormalities, Multiple / Q000209:etiology; D000653:Amniotic Fluid; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology*; D008168:Lung / Q000002:abnormalities*; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications; D012131:Respiratory Insufficiency / Q000209:etiology