Effects of nomifensine (HOE 984) upon psychomotor activity and intracranial self-stimulation in the rat.
The effects of nomifensine maleate (HOE 984) were evaluated using two behavioral tasks. The drug produced dose related increases in both psychomotor activity and operant responding for brain stimulation reward. These results may point to possible psychostimulant properties for the drug.
D000818:Animals; D004567:Electrodes, Implanted; D007546:Isoquinolines / Q000494:pharmacology*; D008297:Male; D009043:Motor Activity / Q000187:drug effects*; D009627:Nomifensine / Q000494:pharmacology*; D051381:Rats; D012653:Self Stimulation / Q000187:drug effects*; D013997:Time Factors
D007546:Isoquinolines; D009627:Nomifensine