title: Comprehensive health care clinic for hemophiliacs.
abstract: One hundred hemophiliacs were examined at a formal comprehensive health care clinic. Sixty-eight percent had abnormal results of liver function tests, and 26% had spleens that were palpable. Measurement of range of motion of knees, ankles, hips, shoulders, and elbows showed a high incidence of hemophilic arthropathy and established a precise baseline by which to judge efficacy of therapy. Results of dental examination disclosed a 14% incidence of multiple severe caries, which is an incidence lower than that of the population as a whole. Examples of inadequate dosage of replacement therapy (16%) and chronic delay in application of self-therapy (14%) were discovered. An 8% incidence of hypertension was noted; prior experience suggests that the combination of hypertension and hemophilia may be lethal. Other clinical and laboratory data also illustrate the importance of a periodic, formally structured, comprehensive examination of hemophiliacs.
mesh_terms: D000293:Adolescent; D000328:Adult; D001900:Boston; D002648:Child; D003191:Comprehensive Health Care / Q000379:methods*; D003729:Dental Care; D006467:Hemophilia A / Q000097:blood / Q000150:complications / Q000628:therapy*; D006511:Hepatitis B Antigens / Q000032:analysis; D006801:Humans; D007263:Infusions, Parenteral; D007592:Joint Diseases / Q000175:diagnosis; D007677:Kidney Function Tests; D008111:Liver Function Tests; D010044:Outpatient Clinics, Hospital; D010949:Plasma; D012651:Self Medication; D013163:Splenomegaly / Q000175:diagnosis
chemical_list: D006511:Hepatitis B Antigens