[Cytophotometric analysis of proteins in human embryo hypophyseal cells in normal and pathologic pregnancies].
As it is known, formation of the adenohypophysis in the human fetus takes place at early stages of ontogenesis. The objective of the present work was to find out whether the adenohypophysis, already at these early stages of development, was capable to response to changes in the environment, in this case to those in the mother's organism. Two groups of the human adenohypophyses obtained as a result of artificial abortion were studied: 1) from fetuses which developed under normal pregnancy; 2) from fetuses which developed under pathological pregnancy (toxemia in the first half of pregnancy). The method of quantitative cytospectrophotometric analysis of simple and conjugated proteins of a various nature were used. The data obtained indicated to early appearance of simple and conjugated proteins in the cells of the anterior lobe of the hypophysis of the human fetus and to their definite dynamics depending upon the course of pregnancy. It was established that at early stages of ontogenesis the adenohypophysis of the human fetus produces a certain reaction to changes in the environment, in particular, to changes occurring in the mother's organism.
D005260:Female; D006651:Histocytochemistry; D006801:Humans; D010902:Pituitary Gland / Q000196:embryology*; D010903:Pituitary Gland, Anterior / Q000196:embryology* / Q000378:metabolism; D011134:Polysaccharides / Q000378:metabolism; D011225:Pre-Eclampsia / Q000378:metabolism*; D011247:Pregnancy; D011506:Proteins / Q000378:metabolism
D011134:Polysaccharides; D011506:Proteins
Tsitofotometricheskiĭ analiz belkov v kletkakh adenogipofiza plodov cheloveka pri normal'noĭ i patologicheskoĭ beremennosti