title: A method of cholecystography applicable to small laboratory animals.
abstract: A method of intraperitoneal cholecystography is described and was tested on mice with experimentally induced gallstones. The presence of stones in the gallbladder was predicted with an accuracy of 95.5%, using doses of 3 ml of 51.6% meglumine iodipamide (Cholografin) per kg diluted 10-fold, followed a few days later by a repeat dose of 5 ml per kg in cases of nonvisualization of the gallbladder. Pilot studies on guinea pigs and rabbits suggest that this method is applicable to these animals too, although a higher dose of contrast medium is required.
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D002765:Cholecystography / Q000379:methods* / Q000401:mortality; D002769:Cholelithiasis / Q000000981:diagnostic imaging; D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D006168:Guinea Pigs; D007274:Injections, Intraperitoneal; D051379:Mice; D011817:Rabbits
chemical_list: D003287:Contrast Media