[Role of exogenous thyrocalcitonin in post-traumatic skin regeneration].
The character and completeness of posttraumatic skin regeneration, as well as the role of fibroblastic cells were studied under the effect of thyrocalcitonine (TCT). By means of cytological, morphological, histochemical autoradiographic, electron microscopic and some biochemical methods, stimulating effect of TCT on the cell proliferation and differentiation in the host regeneration was demonstrated. Application of TCT enhanced the main stages of collagenogenesis that, in its turn, promoted earlier transformation of granulous tissue into connective tissue and stimulated healing of experimental wounds.
D000818:Animals; D002116:Calcitonin / Q000494:pharmacology*; D002454:Cell Differentiation / Q000187:drug effects; D003094:Collagen / Q000096:biosynthesis; D004247:DNA / Q000096:biosynthesis; D005347:Fibroblasts / Q000187:drug effects / Q000648:ultrastructure; D008297:Male; D051381:Rats; D012867:Skin / Q000187:drug effects / Q000293:injuries* / Q000378:metabolism; D014945:Wound Healing / Q000187:drug effects*
D002116:Calcitonin; D003094:Collagen; D004247:DNA
O roli ékzogennogo tirokal'tsitonina v posttravmaticheskoĭ regeneratsii kozhi.