Abnormal carbohydrate composition of the major penetrating membrane protein of En(a-) human erythrocytes.
The major penetrating membrane glycoprotein (band 3) was isolated from En(a-) and normal human erythrocytes. The two proteins differed only in carbohydrate composition. Band 3 from En(a-) erythrocytes contained greater amounts of galactose and N-acetyl-glucosamine. The loss of the sialoglycoprotein sialotetrasaccharides in the En(a-) cell is not compensated by the appearance of these units in band 3 of En(a-) erythrocytes.
D000117:Acetylglucosamine / Q000032:analysis; D002241:Carbohydrates / Q000097:blood*; D002462:Cell Membrane / Q000032:analysis; D002850:Chromatography, Gel; D004913:Erythrocytes, Abnormal / Q000032:analysis*; D005690:Galactose / Q000032:analysis; D006023:Glycoproteins / Q000032:analysis; D006801:Humans
D002241:Carbohydrates; D006023:Glycoproteins; D000117:Acetylglucosamine; D005690:Galactose