Cell division and sister chromatid exchanges in 45,X/46,Xi(Xq) mosaicism.
The kinetics of cell division and sister chromatid exchanges were studied in PHA-stimulated short-term cultivations of peripheral blood by means of the BUDR/FPG technique in controls and in five patients with 45,X/46,X,i(Xq) mosaicism. No significant difference in the length of the cell cycle were observed between 45,X/46,X,i(Xq) and control 46,XX cells. The number of SCE on late i(Xq) was only nonsignificantly elevated (0.6 per i(Xq) against the value expected on the basis of its relative length.
D002453:Cell Cycle; D002842:Chromatids; D005260:Female; D006801:Humans; D037102:Lectins; D009030:Mosaicism; D012729:Sex Chromosome Aberrations; D012730:Sex Chromosomes; D013997:Time Factors; D014960:X Chromosome
D037102:Lectins