title: Specially designed sweeteners and food for diabetics--a real need?
abstract: In the first part of this study, the effect of four isocaloric mixed breakfast meals on the blood glucose and urinary glucose losses was tested in nine adult diabetics and in three healthy subjects, ages 60 to 75. Three of the test meals consisted of a base diet supplemented with applesauce sweetened with sucrose, fructose, or sorbitol. In the fourth test meal, the starch was increased together with saccharine. In the second part of the study, analyses for free glucose and sucrose in several timed food preparations, ordinary as well as food preparations specially designed for diabetics, were performed. The amount of sucrose equivalents (S(eg)) in one ordinary serving of the various products was estimated. No significant differences among sucrose, fructose, and sorbitol-containing meals with respect to the effect on the blood glucose level or on glucosuria were found. The saccharine-containing meal gave a significantly greater blood glucose increase at 60 min only. The amount of sucrose in ordinary marinated foods, such as herring, cucumber, and common beet was negligible. Water-packed fruits supplied one half of the amount of S(eq) or less, compared with fruits packed in sorbitol-sweetened syrup. The amount of S(eq) in the latter products as well as in fruits packed in unsweetened juice equalled that of the fleshy substance of ordinary sucrose-sweetened products. It was concluded that fructose or sorbitol has no advantages over sucrose, as regards the effect on blood glucose in well-regulated adult diabetics, and that it seems unnecessary to have specially sweetened foods designed for diabetics.
mesh_terms: D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000178:diet therapy / Q000378:metabolism; D003927:Diet, Diabetic; D004040:Dietary Carbohydrates / Q000032:analysis; D005069:Evaluation Studies as Topic; D005260:Female; D005396:Fish Products / Q000032:analysis; D005632:Fructose; D005638:Fruit / Q000032:analysis; D006029:Glycosuria / Q000209:etiology; D006801:Humans; D006943:Hyperglycemia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012439:Saccharin; D013012:Sorbitol; D013395:Sucrose / Q000032:analysis; D013549:Sweetening Agents / Q000494:pharmacology; D014675:Vegetables / Q000032:analysis
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D013549:Sweetening Agents; D005632:Fructose; D013012:Sorbitol; D013395:Sucrose; D012439:Saccharin