Coexistence of peculiar pemphigus, myasthenia gravis and malignant thymoma.
An unusual vesculobullous disease and myasthenia gravis occurred concurrently with a malignant thymoma in a Japanese male. The bullous dermatosis had combined clinical and histological features of both dermatitis herpetiformis and pemphigus. Serum showed striated muscle antibodies and intercellular epithelial autoantibodies; the latter had been demonstrated even prior to the development of the skin lesions. Thus, immunologically, this dermatosis was confirmed to be a variety of pemphigus.
D000328:Adult; D000906:Antibodies; D001323:Autoantibodies; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000150:complications*; D010392:Pemphigus / Q000150:complications* / Q000276:immunology / Q000473:pathology; D012867:Skin / Q000473:pathology; D013945:Thymoma / Q000150:complications*; D013953:Thymus Neoplasms / Q000150:complications*
D000906:Antibodies; D001323:Autoantibodies