title: [Circulatory insufficiency in the light of neuroendocrine and metabolic disorders].
abstract: Certain metabolic disorders characterizing disturbances both in neuroendocrine control and in metabolic processes at the cell and tissue levels were revealed in 472 patients with rheumatic heart disease, atherosclerotic cardiosclerosis, and cor pulmonale. The disturbance in the adrenal function was of a dissociated character, manifested by increase in sympathoadrenal and decrease in glucocorticoid activity. The indices of pentosophosphate cycle and erythrocyte and blood serum enzymes studied testify to deep changes in the state of the erythron, marked both by breaks and by adaptation to hypoxia caused by circulatory insufficiency.
mesh_terms: D000293:Adolescent; D000302:Adrenal Cortex / Q000503:physiopathology*; D000328:Adult; D000368:Aged; D001775:Blood Circulation; D003327:Coronary Disease / Q000503:physiopathology; D005260:Female; D006331:Heart Diseases / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011660:Pulmonary Heart Disease / Q000503:physiopathology; D012214:Rheumatic Heart Disease / Q000503:physiopathology; D013564:Sympathetic Nervous System / Q000503:physiopathology*
vernacular_title: Nedostatochnost' krovoobrashcheniia v svete neiro-endokrinnykh i obmennykh narusheniĭ.