[Experiences with continuous infusions of etomidate in cardiac surgery (author's transl)].
The hypnotic agent etomidate was added by infusion to a fentanyl-N2O-O2-anaesthesia for patients (n=15) requiring open heart surgery. The purpose of this procedure was to avoid awareness during operation (mean duration 187 min). The average amount of etomidate infused was 2.55 mg/kg, which seemed to be an overdose. The fentanyl consumption was slightly reduced as compared with a control group. No patients complained of awareness. The anaesthetic method studied is not thought to be superior to a high-dose fentanyl anaesthesia.
D006348:Cardiac Surgical Procedures; D005283:Fentanyl; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D007093:Imidazoles / Q000008:administration & dosage / Q000494:pharmacology*; D007275:Injections, Intravenous; D008568:Memory / Q000187:drug effects; D013997:Time Factors
D006993:Hypnotics and Sedatives; D007093:Imidazoles; D005283:Fentanyl
Erfahrungen mit der Etomidate-Dauerinfusion in der Herzchirurgie