title: Juvenile glaucoma associated with goniodysgenesis.
abstract: Clinicopathologic studies, including electron microscopy, of trabeculectomy and peripheral iridectomy specimens from three patients with "juvenile" glaucoma revealed varying forms of maldevlopment of the chamber angle in all cases. A 20-year-old white woman (Case 1) had associated iridogoniodysgenesis with a pseudopolycoria-like iris pattern. In a 39-year-old white woman (Case 2), goniodysgenesis was associated with degenerated cell remnants in the angle "cleavage" area. A 15-year-old mentally retarded white boy (Case 3) displayed features of juvenile pigmentary glaucoma with associated goniodysgenesis and megalocornea.
mesh_terms: D000293:Adolescent; D000328:Adult; D000867:Anterior Chamber / Q000002:abnormalities*; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000473:pathology; D003316:Corneal Diseases / Q000150:complications; D003886:Descemet Membrane / Q000473:pathology / Q000648:ultrastructure; D005260:Female; D005901:Glaucoma / Q000150:complications / Q000473:pathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007498:Iris / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D014602:Uvea / Q000473:pathology / Q000648:ultrastructure