title: Brain and spinal cord lesions in the newborn rat.
abstract: Previous studies involving the induction of central nervous system lesions in animals have required complex, expensive equipment including sterotaxis and an operating microscope. This study describes a technique for producing telencephalic (forebrain) lesions in the developing rat by the use of copper wire. In addition, a nonvisual method of producing spinal cord transections in the young rat is discussed. Both techniques have a high succes rate and minimal mortality.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001927:Brain Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D051381:Rats; D012376:Rodent Diseases / Q000209:etiology* / Q000473:pathology; D013116:Spinal Cord / Q000473:pathology; D013118:Spinal Cord Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D013687:Telencephalon / Q000473:pathology