The formation of alanine from amino acids in diaphragm muscle of the rat.
Alanine production and pyruvate content of the isolated rat hemidiaphragm are increased by isoleucine or glutamate. These results support the hypothesis that amino acids are converted into pyruvate before oxidation and that some pyruvate is transaminated to alanine, which is released from the muscle.
D000409:Alanine / Q000096:biosynthesis*; D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D003964:Diaphragm / Q000378:metabolism; D005971:Glutamates / Q000378:metabolism; D066298:In Vitro Techniques; D007532:Isoleucine / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000378:metabolism*; D051381:Rats
D000596:Amino Acids; D005971:Glutamates; D007532:Isoleucine; D000409:Alanine