[Role of microcirculatory changes in contractile insufficiency of the intact myocardial zones in acute period of myocardial infarct].
To determine the role of the microcirculation channel in the genesis of contractile insufficiency of "intact" myocardial zones in infarction the ultrastructural organization of the blood capillaries and the myocardial myocytes was compared in 14 patients between the ages of 51 and 85 who had died in the acute period of the disease. Myocardial tissue of 26 areas of the left and right ventricles and the right atrium was collected for examination during biopsy of the heart in the zone supplied by the "intact" coronary artery 15-30 minutes after death of acute transmural myocardial infarction. The reduction in the microcirculation channel and the degree of myocyte damage down to the development of foci of micronecrosis were most manifest in cases with vast transmural infarction complicated by pulmonary edema and true cardiogenic shock.
D000208:Acute Disease; D000368:Aged; D002196:Capillaries / Q000648:ultrastructure; D003326:Coronary Circulation; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation; D008854:Microscopy, Electron; D008875:Middle Aged; D009200:Myocardial Contraction; D009203:Myocardial Infarction / Q000473:pathology / Q000503:physiopathology*
Rol'mikrotsirkuliatornykh izmeneniĭ v sokratitel'noĭ nedostatochnosti neporazhennykh otdelov miokarda v ostrom periode infarkta.