Amelioration of insulin lipoatrophy by dexamethasone injection.
Widespread subcutaneous lipoatrophy occurred in a 47-year-old woman after subcutaneous injections of isophane insulin suspension for five months. Subsequent systemic treatment with a dexamethasone (0.08 mg/day) insulin mixture injected subcutaneously into the depressed areas resulted in an impressive return of subcutaneous tissue after eight months of continuous therapy.
D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use*; D003920:Diabetes Mellitus / Q000188:drug therapy; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D007328:Insulin / Q000009:adverse effects* / Q000627:therapeutic use; D008060:Lipodystrophy / Q000139:chemically induced / Q000188:drug therapy*; D008875:Middle Aged
D007328:Insulin; D003907:Dexamethasone