Influence of drugs on clinical chemical data for serum glucose, investigated with the automated glucose oxidase-perid method.
Fifty drugs, applied in the therapy of internal diseases, were investigated for their effect on the clinical chemical determination of serum glucose by the automated GOD-Perid method. The results showed a statistically significant depression of the reported glucose value, by 7 drugs containing the pyrazolone group and its derivatives (Baralgin, Butazolidine, Analgin, Novalgetol, Analgocain, Irgapyrin, Aminopyrin) P less than 0.001; P less than 0.01. The influence depends on the quantity of drug and on the time interval between loading and glucose analysis.
D001322:Autoanalysis / Q000379:methods; D001786:Blood Glucose / Q000032:analysis*; D005949:Glucose Oxidase; D006801:Humans; D004364:Pharmaceutical Preparations
D001786:Blood Glucose; D004364:Pharmaceutical Preparations; D005949:Glucose Oxidase