title: Postmortem delineation of infarcted myocardium. Coronary perfusion with nitro blue tetrazolium.
abstract: Perfusion of hearts with nitro blue tetrazolium resulted in gross formazan staining of intact myocardium, while infarcted zones and scars were unstained or were poorly stained. Subsequent perfusion with 3.7% formaldehyde solution provided a rigid specimen with well-preserved anatomical structures and landmarks suitable for detailed correlation of three-dimensional infarct distribution with clinical data. Specimens are particularly amenable to further gross dissection of mapping of lesions from interval slices, or both.
mesh_terms: D000208:Acute Disease; D000818:Animals; D004285:Dogs; D006801:Humans; D009203:Myocardial Infarction / Q000473:pathology*; D009206:Myocardium / Q000473:pathology; D009580:Nitroblue Tetrazolium; D010477:Perfusion; D013778:Tetrazolium Salts
chemical_list: D013778:Tetrazolium Salts; D009580:Nitroblue Tetrazolium