[Permeability-increasing effect of punctates. 3. Inhibition of the permeability-increasing activity by contrykal].
The punctate of the pleural cavity of a patient was examined which very much increased the permeability of the membrane in the animal experiment. Proteases is ascribed the effect increasing permeability, which are adsorbed to macromolecules. The increase of permeability could be inhibited by contrycal. An increase of permeability by proteolytic enzymes is discussed as one of the possible pathomechanisms for the development of exudations.
D000818:Animals; D002463:Cell Membrane Permeability / Q000187:drug effects*; D004487:Edema / Q000188:drug therapy; D005122:Exudates and Transudates / Q000378:metabolism; D006801:Humans; D010447:Peptide Hydrolases / Q000494:pharmacology / Q000627:therapeutic use; D010994:Pleura; D011817:Rabbits; D014361:Trypsin Inhibitors / Q000494:pharmacology*
D014361:Trypsin Inhibitors; D010447:Peptide Hydrolases
Permeationssteigernde Wirkung von Punktaten 3. Mitteliung: Hemmung permeationssteigernder Aktivität durch Contrykal