[Cell precursors of fibroblasts detected by cloning in vitro hematopoietic organ crlls of normal and irradiated mice].
Fibroblast colonies (clones) are formed in monolayer cultures of the bone marrow, spleen and thymus cells from adult mice, the colony-forming efficiency (per 105 cells) was 2.2, 0.2 and 0.16, respectively. About 50% of the bone marrow CFU-F were destroyed immediately after the total body irradiation with 150r; the following 6 days the number of CFU-F decreased to 10% of the normal value. The normal level of the CUF-F concentration was reached in the bone marrow on the 25th postirradiation day.
D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects; D002455:Cell Division; D002999:Clone Cells; D006412:Hematopoietic Stem Cells; D066298:In Vitro Techniques; D051379:Mice; D011830:Radiation Effects; D013154:Spleen / Q000528:radiation effects; D013950:Thymus Gland / Q000528:radiation effects
Kletki-predshestvenniki fibroblastov, vyiavliaemye metodom klonirovaniis in vitro kletok krovetvornykh organov normal"nykh i obluchennykh mysheĭ