[Effect of quercitrin on structural changes in the large and small intestines in experimental enterocolitis].
Sensitization of rats with the homologous antigen of the large intestine with Freund's stimulant caused marked immunomorphological shift in the large intestine of rats with the phenomena of enteritis in the small intestine. Oral administration of quercitrin in doses of 25 and 100mg/kg for 10 days promoted decline of focal lymphohistiomonocytic infiltrations, of eosinophilic in the mucosa and of scleroti changes in the large intestine. At the same time restoration of structural disturbances occurred in the small intestine. The influence of quercitrin on the morphological changes in the epithelium of the large and small intestine mucosa were insignificant. It is believed that the therapeutic action of quercitrin could be caused by restoration of local circulation deranged in animal sensitization.
D000818:Animals; D004761:Enterocolitis, Pseudomembranous / Q000188:drug therapy* / Q000209:etiology; D005419:Flavonoids / Q000627:therapeutic use*; D006967:Hypersensitivity / Q000150:complications / Q000188:drug therapy; D007420:Intestine, Large / Q000187:drug effects*; D007421:Intestine, Small / Q000187:drug effects*; D008297:Male; D011794:Quercetin / Q000627:therapeutic use*; D051381:Rats
D005419:Flavonoids; D011794:Quercetin
Vliianie kvertsitrina na strukturnye izmeneniia v tolstoĭ i tonkoĭ kishkakh pri éksperimental'nom énterokolite