title: Developmental anomalies in a human fetus of 17 weeks' gestational age.
abstract: Chromosome studies of a therapeutically aborted male fetus, after amniocentesis of a 41-year-old woman, showed an abnormal karyotype of 47, XY, + 18. The fetus had many of the external anomalies described in newborns with trisomy 18; macrodissection revealed many internal anomalies consistent with this syndrome. The external and internal findings are described.
mesh_terms: D000328:Adult; D001835:Body Weight; D002902:Chromosomes, Human, 16-18; D005260:Female; D005333:Fetus / Q000033:anatomy & histology / Q000473:pathology; D005865:Gestational Age; D006801:Humans; D008297:Male; D011247:Pregnancy; D013997:Time Factors; D014314:Trisomy