Coombs-positive hemolytic uremic syndrome.
Two children presenting typical clinical features of the hemolytic-uremic syndrome had a positive direct Coombs test that remained positive throughout the illness. It is probable that an upper respiratory tract infection precipitated an antigen-antibody reaction that caused the autoimmune hemolytic anemia and immune-complex glomerulonephritis.
D000208:Acute Disease; D000937:Antigen-Antibody Reactions; D001706:Biopsy; D002675:Child, Preschool; D003298:Coombs Test; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000150:complications / Q000276:immunology*; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D012141:Respiratory Tract Infections / Q000150:complications / Q000276:immunology