Specialized blood filters and fresh whole blood.
Platelet counts and platelet functions were determined in fresh whole blood before and after it passed through two types of specialized transfusion filters. Both filters were capable of trapping 20% to 40% of the functional platelets, necessary for hemostasis, especially if heparin was used as the anticoagulant. When fresh whole blood is needed to treat the bleeding patient who has already received massive blood transfusions, these specialized filters should probably not be used.
D001792:Blood Platelets; D001803:Blood Transfusion / Q000295:instrumentation*; D005374:Filtration / Q000295:instrumentation*; D006470:Hemorrhage / Q000628:therapy; D006487:Hemostasis; D006801:Humans