Isolation of (-)-cryptosporiospin, a chlorinated cyclopentenone fungitoxic metabolite from Phialophora asteris f. sp. helianthi.
The (-)-enantiomer of cryptosporiopsin, a chlorinated cyclopentenone fungitoxic metabolite, was isolated from Phialophora asteris f. sp. helianthi. Next to a comparable fungitoxic activity was shown by crypstosporiopsin, the product particularly inhibits growth of Sclerotinia sclerotiorum, an important pathogen on sunflower. Two further metabolites were tentatively identified as a stereoisomer of cryptosporiopsin and its dehydrated derivative.
D000935:Antifungal Agents / Q000302:isolation & purification*; D001203:Ascomycota; D055598:Chemical Phenomena; D002621:Chemistry; D003517:Cyclopentanes / Q000302:isolation & purification*; D010676:Phialophora / Q000032:analysis*; D013237:Stereoisomerism
D000935:Antifungal Agents; D003517:Cyclopentanes; C010093:cryptosporiopsin