title: The influence of hypercalcemia on basal and cholecystokinin-stimulated pancreatic, gallbladder, and gastric functions in man.
abstract: Hypercalcemia produced in normal volunteers by intravenous infusions of CaCl2 increased outputs of pancreatic enzyme and gastric acid. Further, hypercalcemia enhanced cholecystokinin (CCK)-stimulated pancreatic enzyme secretion and gallbladder contraction. Our results suggest that hypercalcemia affects pancreatic, gallbladder, and gastric functions as well as their responses to exogenous CCK.
mesh_terms: D000328:Adult; D001663:Bilirubin / Q000378:metabolism; D002766:Cholecystokinin / Q000494:pharmacology*; D005704:Gallbladder / Q000187:drug effects / Q000503:physiopathology*; D005750:Gastric Juice / Q000378:metabolism; D005753:Gastric Mucosa / Q000187:drug effects; D005755:Gastrins / Q000097:blood; D006801:Humans; D006934:Hypercalcemia / Q000503:physiopathology*; D008297:Male; D010179:Pancreas / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology*; D010189:Pancreatic Juice / Q000378:metabolism; D013270:Stomach / Q000503:physiopathology*
chemical_list: D005755:Gastrins; D002766:Cholecystokinin; D001663:Bilirubin