Andrenergic reactivity of the gastro-intestinal tract. I. Fundus of the rat's stomach.
The adrenergic receptors of the fundus of rat stomach are both type alpha and type beta. Activation of the alpha-adrenergic receptors gives a diphasic response in which inhibition precedes excitation. The beta-adrenergic receptors mediate exclusively inhibitory response; the beta-adrenergic component of the inhibitory response is clearly observed only when the alpha-adrenergic component is diminished. The beta-receptors can be assigned, with some reserve, to the betaalpha group.
D000818:Animals; D003042:Cocaine / Q000494:pharmacology*; D003983:Dibenzylchlorethamine / Q000494:pharmacology*; D004837:Epinephrine / Q000494:pharmacology*; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects*; D013270:Stomach / Q000187:drug effects*
D011941:Receptors, Adrenergic; D003983:Dibenzylchlorethamine; D011433:Propranolol; D003042:Cocaine; D009638:Norepinephrine; D004837:Epinephrine
Reattività adrenergica nel tratto gastro-enterico. Nota I - Fundus di stomaco di ratto.