title: Influence of gonadal hormones on the developing amphibian brain: changes in ribonucleic acid, protein and activity levels of acetylcholinesterase on in vivo administration of progesterone.
abstract: The levels of RNA and protein and activity levels of acetylcholinesterase decreased in the brain of developing tadpoles of 13-15-day-old Bufo melanostictus on in vivo administration of progesterone (200 mug/0.1 ml refined peanut oil). These changes suggest decelaration in the activity of the protein-synthetic machinery in progesterone administered animals.
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D002025:Bufonidae; D007814:Larva; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D011374:Progesterone / Q000494:pharmacology*; D012313:RNA / Q000096:biosynthesis*
chemical_list: D009419:Nerve Tissue Proteins; D011374:Progesterone; D012313:RNA; D000110:Acetylcholinesterase