Samarosporin, a new peptide antibiotic. I. Fermentation, isolation ahd characterization.
A new antibiotic, samarosporin, was isolated in a crystalline state from a mycelial extract of a strain of Samarospora species (an ascomycete). Samarosporin is a neutral cyclopeptide and has a molecular formula of C72H111N15O19. Samarosporin shows a broad antimicrobial activity against various test microorganisms.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000302:isolation & purification / Q000494:pharmacology; D001203:Ascomycota / Q000378:metabolism; D001419:Bacteria / Q000187:drug effects; D003460:Crystallization; D005285:Fermentation; D007928:Lethal Dose 50; D051379:Mice; D010455:Peptides / Q000302:isolation & purification / Q000494:pharmacology
D000596:Amino Acids; D000900:Anti-Bacterial Agents; D010455:Peptides