Comparison of human adult and fetal hemoglobin: aminophenol-induced methemoglobin formation.
Human fetal hemoglobin was more susceptible to methemoglobin formation in the presence of aminophenols than was adult hemoglobin. This was due to the intrinsic properties of the proteins rather than the presence of methemoglobin reductases.
D000328:Adult; D000814:Aniline Compounds / Q000494:pharmacology*; D005319:Fetal Hemoglobin / Q000378:metabolism*; D006441:Hemoglobin A / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D008706:Methemoglobin / Q000096:biosynthesis*; D010636:Phenols / Q000494:pharmacology*
D000814:Aniline Compounds; D006454:Hemoglobins; D010636:Phenols; D008706:Methemoglobin; D006441:Hemoglobin A; D005319:Fetal Hemoglobin