title: Abnormalities of detrusor and sphincter function in multiple sclerosis.
abstract: Bladder and urethral function was studied in 52 patients with multiple sclerosis using gas-cystometry combined with sphincter electromyography. 96% of the patients showed abnormalities of either detrusor or sphincter function. The abnormal patterns discovered indicated demyelinating lesions in the corticospinal as well as in the reticulospinal tract. Urgency and urge-incontinence were the predominant symptoms, whereas no signs of involvement of the upper urinary tract found. The use of gas-cystometry provides a fast and differentiated method for assessment of the detrusor function.
mesh_terms: D000328:Adult; D000368:Aged; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications*; D009129:Muscle Tonus; D009130:Muscle, Smooth / Q000503:physiopathology; D011312:Pressure; D012018:Reflex; D001750:Urinary Bladder, Neurogenic / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D014555:Urination Disorders / Q000209:etiology; D014836:Volition