title: Experimental hydrocephalus following mechanical increment of intraventricular pulse pressure.
abstract: Experimental hydrocephalus has been induced in lambs by artificial increase of the amplitude of intraventricular cerebrospinal fluid (CSF) oscillations related to arterial pulsations, without concomitant changes of the mean CSF-pressure. The characteristics of this hydrocephalus demonstrate that the intraventricular CSF-pulsations can play a role in the genesis of ventricular dilation. Such a method may be used to produce an original model of hydrocephalus independent of changes of CSF-circulation or absorption.
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D006849:Hydrocephalus / Q000134:cerebrospinal fluid*; D011312:Pressure; D011674:Pulse; D012756:Sheep