title: [Biological compatibility of soft contact lens materials (HEMA) (author's transl)].
abstract: After implanting a disc (0,25 mm thickness and 1,5 mm diameter) of soft contact lens materials ("Soflens", "Hydroflex", "Hydron") in the anterior chamber of rabbits through a lancet incision, the reactions of iris, aqueous and cornea were observed for six months at regular intervals with slit lamp photograph. At the place where the disc touched the iris one could see during half a year periodic hyperaemia iridis and foreign-substance-granuloma of the iris. The cause of these reactions is a toxin in the HEMA. The reactions are more intense than with PMMA.
mesh_terms: D000818:Animals; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects*; D005547:Foreign Bodies; D006099:Granuloma / Q000209:etiology; D006940:Hyperemia / Q000139:chemically induced; D007500:Iritis / Q000209:etiology; D011102:Polyhydroxyethyl Methacrylate / Q000009:adverse effects; D011817:Rabbits; D013997:Time Factors; D014603:Uveal Diseases / Q000209:etiology
chemical_list: D011102:Polyhydroxyethyl Methacrylate
vernacular_title: Zur biologischen Verträglichkeit von weichen Kontaktlinsenmaterialien (HEMA).