The stability of short ragweed pollen extract as measured by skin test and antigen E.
A short ragweed pollen extract stored at 4 degrees C was shown to retain its skin reactivity for 18 mo, although 60% of the antigen E was lost. When stored at higher temperatures, the extracts had a markedly reduced skin reactivity for some individuals, but retained full reactivity in others even though the antigen E was markedly diminished. Thus, some ragweed-sensitive individuals are very sensitive to antigen E, which is heat-labile, but some have a major sensitivity to other allergens, which are heat-stable. During the 18-mo course of this study, skin test reactions to a similar extract did not show significant variability.
D000293:Adolescent; D000328:Adult; D004355:Drug Stability; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000032:analysis*; D010944:Plants / Q000276:immunology*; D011058:Pollen / Q000032:analysis; D012882:Skin Tests; D013696:Temperature; D013997:Time Factors
D010936:Plant Extracts