[Pseudo-anaphylactic reaction to procaine-penicillin G. 3 cases of Hoigne's syndrome].
On the basis of three cases, the authors review the clinical picture of Hoigne's syndrome, characterised by the development of acute manifestations, essentially psycho-sensorial, immediately following the injection of procaine penicillin G (PPG). The syndrome is due to the passage into the circulation of micro-aggregates of PPG and has no immuno-allergic basis. Subsequent treatment with penicillin is not contraindicated.
D000328:Adult; D001007:Anxiety / Q000139:chemically induced; D001794:Blood Pressure / Q000187:drug effects; D003937:Diagnosis, Differential; D004342:Drug Hypersensitivity / Q000175:diagnosis; D005260:Female; D006212:Hallucinations / Q000139:chemically induced; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects; D008619:Mepivacaine / Q000009:adverse effects; D009461:Neurologic Manifestations; D010402:Penicillin G Procaine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D013610:Tachycardia / Q000139:chemically induced; D014012:Tinnitus / Q000139:chemically induced
D010402:Penicillin G Procaine; D008619:Mepivacaine
Réaction pseudo-anaphylactique à la procaïne-pénicilline G. Trois cas de syndrome de Hoigné