Sarcoid-like lesions in the lung by selective intrabronchial instillation of antigen in previously sensitized rabbits.
Sarcoid-like lesions were observed in the lung after selective intrabronchial instillation of antigen in previously sensitized rabbits. These lesions consisted of an early exudative phase, an intermediate phase of interstitial pneumonia and a late proliferative phase. Sarcoid-like granulomas, similar to granuloma, in human lung developed during the late phase.
D000818:Animals; D000941:Antigens; D001980:Bronchi / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D006099:Granuloma / Q000473:pathology; D006644:Histiocytes; D008168:Lung / Q000473:pathology*; D008214:Lymphocytes; D008264:Macrophages; D010950:Plasma Cells; D011817:Rabbits; D012130:Respiratory Hypersensitivity / Q000473:pathology*
D000941:Antigens