The relative effects of selective intra-arterial and intravenous vasopressin infusion.
The relative effects of selective intra-arterial and intravenous infusions of vasopressin were evaluated in 16 normotesive dogs. One group was infused via the left gastric artery, one was infused via a peripheral vein, and a control group was not infused. Flow to the stomach and bowel was reduced by an average of 73% and 45%, respectively. There was no significant difference between selective intra-arterial and intravenous infusions with regard to their effects on visceral flow or their systemic parameters. Control animals demonstrated only minor variations from base-line flow.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D004064:Digestive System / Q000098:blood supply*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D007263:Infusions, Parenteral; D007269:Injections, Intra-Arterial; D007668:Kidney / Q000098:blood supply; D008099:Liver / Q000098:blood supply; D012039:Regional Blood Flow / Q000187:drug effects; D014667:Vasopressins / Q000008:administration & dosage / Q000494:pharmacology*
D014667:Vasopressins