Stimulatory effect of dihydroxyphenyl compounds on the aerotolerance of Spirillum volutans and Campylobacter fetus subspecies jejuni.
The aerotolerance of the microaerophilic bacterium Spirillum volutans was greatly stimulated in a defined medium by the presence of dihydroxyphenyl ferric iron-binding compounds such as nor-epinephrine at 10(-5) to 10(-6) M. Dihydroxyphenyl compounds at 2 X 10(-4) M, or iron salts (ferrous or ferric) at high concentration, greatly increased the aerotolerance of a strain of Campylobacter fetus subsp. jejuni when grown on streak plates of Brucella agar. The results suggest that the microaerophilism of these organisms might in part be caused by a failure to synthesize microbial ferric iron-binding compounds at sufficient levels to support aerobic growth.
D000332:Aerobiosis / Q000187:drug effects; D002167:Campylobacter / Q000254:growth & development*; D002168:Campylobacter fetus / Q000254:growth & development* / Q000378:metabolism; D004295:Dihydroxyphenylalanine / Q000494:pharmacology*; D004837:Epinephrine / Q000494:pharmacology*; D007501:Iron / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology*; D010100:Oxygen; D010313:Partial Pressure; D012492:Salts; D013139:Spirillum / Q000254:growth & development* / Q000378:metabolism
D012492:Salts; D004295:Dihydroxyphenylalanine; D007501:Iron; D010100:Oxygen; D009638:Norepinephrine; D004837:Epinephrine