title: Measuring barbiturates, sedatives, and anticonvulsants in serum by gas-liquid chromatography.
abstract: We describe a method for measuring therapeutic and overdose levels of barbiturate, sedative, and anticonvulsant drugs in serum by gas-liquid chromatography (GLC). This method is a unique combination of techniques including a simple extraction, cochromatography of the specimen with authentic carrier drugs, and the use of multiple dissimilar gas chromatographic columns. In this way, a large number of drugs may be identified and quantitated without confusion.
mesh_terms: D000927:Anticonvulsants / Q000097:blood*; D001463:Barbiturates / Q000097:blood*; D002849:Chromatography, Gas / Q000379:methods; D006801:Humans; D006993:Hypnotics and Sedatives / Q000097:blood*
chemical_list: D000927:Anticonvulsants; D001463:Barbiturates; D006993:Hypnotics and Sedatives