Enhanced hepatotoxicity of dimethylnitrosamine by pretreatment of rats with the antioxidant ethoxyquin.
D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000473:pathology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004032:Diet; D004128:Dimethylnitrosamine / Q000009:adverse effects*; D004357:Drug Synergism; D005015:Ethoxyquin / Q000378:metabolism / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism / Q000473:pathology; D008297:Male; D009602:Nitrosamines / Q000009:adverse effects*; D009929:Organ Size / Q000187:drug effects; D011506:Proteins / Q000378:metabolism; D011804:Quinolines / Q000494:pharmacology*; D051381:Rats
D009602:Nitrosamines; D011506:Proteins; D011804:Quinolines; D003577:Cytochrome P-450 Enzyme System; D005015:Ethoxyquin; D001219:Aspartate Aminotransferases; D004128:Dimethylnitrosamine