Alkaloids and coumarins of Thamnosma montana.
From the turpentine broom, Thamnosma montana, four alkaloids and three coumarins were isolated and characterized. Skimmianine (5), N-methyl-acridone (4) and 5-(3'-methyl-2',3'-dihydroxybutanyl)-8-methoxypsoralen (1) were obtained previously from T. montana. Robustine (2) is reported from a Thamnosma species for the first time and acridone (6), thamnosmonin (9), and thamontanin (14) are reported from a natural source for the first time. Evidence for the structures of the new isolates is presented.
D000470:Alkaloids / Q000032:analysis* / Q000627:therapeutic use; D002277:Carcinoma / Q000188:drug therapy; D002460:Cell Line; D055598:Chemical Phenomena; D002621:Chemistry; D003374:Coumarins / Q000032:analysis*; D007945:Leukemia, Lymphoid / Q000188:drug therapy; D008730:Methoxsalen / Q000032:analysis; D009062:Mouth Neoplasms / Q000188:drug therapy; D009374:Neoplasms, Experimental / Q000188:drug therapy; D010946:Plants, Medicinal / Q000032:analysis*
D000470:Alkaloids; D003374:Coumarins; D008730:Methoxsalen