Practical considerations in the development of a human cancer vaccine.
Factors involved in the development of a human oncornavirus vaccine are discussed. The isolation and purification of subviral gp69/71 antigenic components enhance the feasibility of developing safe vaccine. The recent isolation of a C-type virus (the HL-23) from a human leukemic patient and its similarity to the simian sarcoma virus presents us with a unique opportunity to test the safety and potency of a vaccine in nonhuman primates.
D000818:Animals; D006801:Humans; D009369:Neoplasms / Q000517:prevention & control*; D014764:Viral Proteins / Q000032:analysis; D014765:Viral Vaccines
D014764:Viral Proteins; D014765:Viral Vaccines