Response of adnexal glands to testosterone stimulation in the normal adult male.
Normal male volunteers were studied in order to set up a functional exploration test based on administration of testosterone propionate for use on the adnexal glands of the male genital tract. Seminal acid phosphatase and citric acid levels showed no significant variations compared with spontaneous physiologic oscillations. Concentration and total quantity of fructose were considerably reduced. Alkaline phosphatase showed an intermediate pattern with constant values of concentration and decrease of total quantity. The hypothesis is advanced that adnexal glands possess a secretory metabolism with a maximal basal response to androgen stimulation, but with a different mechanism of action: partly adaptable at the level of the prostate and of the "all or nothing" type at the level of the vesicles.
D000135:Acid Phosphatase / Q000032:analysis; D000328:Adult; D000469:Alkaline Phosphatase / Q000032:analysis; D002951:Citrates / Q000032:analysis; D004822:Epididymis / Q000187:drug effects* / Q000201:enzymology; D005632:Fructose / Q000032:analysis; D006801:Humans; D008297:Male; D012661:Semen / Q000032:analysis* / Q000187:drug effects / Q000201:enzymology; D013268:Stimulation, Chemical; D013739:Testosterone / Q000494:pharmacology*
D002951:Citrates; D005632:Fructose; D013739:Testosterone; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase