Protective effect of allopurinol in renal ischemia.
We have confirmed earlier findings that treatment with allopurinol offers some protection to the kidney from ischemic damage caused by total interruption of renal circulation. With this evidence, a clinical trial is warranted, particularly when periods of warm ischemia are unavoidable.
D000493:Allopurinol / Q000627:therapeutic use*; D000818:Animals; D004285:Dogs; D005260:Female; D007511:Ischemia / Q000188:drug therapy*; D007668:Kidney / Q000098:blood supply*; D008297:Male
D000493:Allopurinol