title: Medicated intrauterine devices to improve bleeding events.
abstract: In an attempt to find an IUD that will cause a minimum amount of blood loss, while continuing to be effective and easily retained, we are studying 4 medicated IUDs: a copper-bearing Lipps Loop, a Copper-T-200, a progesterone-releasing U-coil, and a tranexamic-acid-releasing Lippes Loop. Inert devices of the same shape and size are used as controls. This is a comparison of the findings on menstrual blood loss and loss and changes in bleeding patterns for patients using the plain and copper-bearing Lippes Loops. Preliminary results for the progesterone-bearing U-coil and the tranexamic-acid-releasing Lippes Loop are also given, but studies of these devices are not yet complete.
mesh_terms: D005260:Female; D006470:Hemorrhage / Q000517:prevention & control; D006801:Humans; D007434:Intrauterine Devices; D007435:Intrauterine Devices, Copper; D007436:Intrauterine Devices, Medicated; D008598:Menstruation; D011374:Progesterone; D014148:Tranexamic Acid
chemical_list: D011374:Progesterone; D014148:Tranexamic Acid