Effect of methylglucamine salts of iocarmic and iothalamic acids on hemodynamics, acid-base equilibrium and coagulation.
The effects of electrolytes, osmolality, pH, PaO2, PaCO2, hematocrit, blood volume and coagulation occurring after a rapid intra-aortic injection of a monomer and a dimer (salts of methylglucamine of the iothalamic and iocarmic acids) were compared. The effects of the monomer agreed with previous results but the effects of the dimer differed from those reported in the literature.
D000136:Acid-Base Equilibrium / Q000187:drug effects*; D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D001794:Blood Pressure / Q000187:drug effects; D001810:Blood Volume / Q000187:drug effects; D002245:Carbon Dioxide / Q000097:blood; D004285:Dogs; D006400:Hematocrit; D006439:Hemodynamics / Q000187:drug effects*; D007269:Injections, Intra-Arterial; D007482:Iothalamate Meglumine / Q000008:administration & dosage / Q000633:toxicity*; D009994:Osmolar Concentration; D010100:Oxygen / Q000097:blood; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood
D002245:Carbon Dioxide; D012964:Sodium; D011188:Potassium; D010100:Oxygen; D007482:Iothalamate Meglumine