[Protection against acute renal insufficiency by means of forced diuresis in an ischemic rat model].
Renal ischemia of 90 min duration provokes initial oliguria and hyperazotemia; however, in rats with high diuresis, with or without renal renin depletion, protection against acute renal failure is observed in this model. The protection is directly proportional to the diuresis.
D058186:Acute Kidney Injury / Q000209:etiology / Q000517:prevention & control*; D000818:Animals; D003404:Creatinine / Q000097:blood; D003900:Desoxycorticosterone / Q000627:therapeutic use; D004195:Disease Models, Animal; D004231:Diuresis / Q000187:drug effects*; D005665:Furosemide / Q000627:therapeutic use; D007511:Ischemia / Q000150:complications; D051381:Rats; D012083:Renin / Q000032:analysis; D012965:Sodium Chloride / Q000494:pharmacology
D003900:Desoxycorticosterone; D012965:Sodium Chloride; D005665:Furosemide; D003404:Creatinine; D012083:Renin
Protection contre l'insuffisance rénale aiguë par une diurèse forcée dans un modèle ischémique chez le rat.