Biological evaluation of biomaterials for cardiovascular applications: some current results.
The proper biologic evaluation of biomaterials for blood-contacting applications must include considerations of hemorheologic parameters, species-related differences, and damages to the reticuloendothelial system. Although there are no materials currently available that are completely blood compatible, several smooth-surfaced polymers are quite tolerable in the physiological environment. These include chemically grafted polyacrylamide hydrogels, glow-discharge polymers of silica-free hexamethldisiloxane, and ethyl cellulose perfluorobutyrate.
D000178:Acrylamides / Q000592:standards; D000818:Animals; D001672:Biocompatible Materials / Q000592:standards*; D002482:Cellulose / Q000031:analogs & derivatives / Q000592:standards; D004285:Dogs; D005069:Evaluation Studies as Topic; D005466:Fluorocarbons / Q000592:standards; D006493:Heparin; D006801:Humans; D011108:Polymers / Q000592:standards*; D000644:Quaternary Ammonium Compounds; D012082:Renal Veins; D012821:Silanes / Q000592:standards; D012833:Siloxanes / Q000592:standards; D013923:Thromboembolism / Q000209:etiology*; D014684:Venae Cavae
D000178:Acrylamides; D001672:Biocompatible Materials; D005466:Fluorocarbons; D011108:Polymers; D000644:Quaternary Ammonium Compounds; D012821:Silanes; D012833:Siloxanes; D002482:Cellulose; D006493:Heparin