title: Molecular evolution of 5S RNA.
abstract: Based on the comparative analyses of the primary structure of 5S RNAs from 19 organisms, a secondary structure model of 5S RNA is proposed. 5S RNA has essentially the same structure among all prokaryotic species. The same is true for eukaryotic 5S RNAs. Prokaryotic and eukaryotic 5S RNAs are also quite similar to each other, except for a difference in a specific region. By comparing the nucleotide alignment from the juxtaposed 5S RNA secondary structures, a phylogenic tree of nineteen organisms was constructed. The time of divergence between prokaryotes and eukaryotes was estimated to be 2.5 X 10(9) years ago (minimum estimate: 2.1 X 10(9).
mesh_terms: D001483:Base Sequence; D008961:Models, Structural; D009690:Nucleic Acid Conformation; D010802:Phylogeny; D012313:RNA; D012329:RNA, Bacterial; D013045:Species Specificity
chemical_list: D012329:RNA, Bacterial; D012313:RNA