On a molecular, microscale fingerprinting of gangliosides.
Mass spectrometry of intact ganglioside derivatives has been shown to afford a specific information on type, number and sequence of sugars, as well as ceramide structure. This is illustrated here for a hematoside with N-glycolylneuraminic acid and a disialyldihexosylceramide. As shown elsewhere, this novel technique, needing only 10 micrograms for a spectrum, is generally applicable to all types of glycolipids, including complex blood group fucolipids.
D000818:Animals; D002241:Carbohydrates / Q000032:analysis; D002417:Cattle; D004912:Erythrocytes / Q000032:analysis; D005227:Fatty Acids / Q000032:analysis; D005732:Gangliosides / Q000032:analysis; D006736:Horses; D013058:Mass Spectrometry; D008970:Molecular Weight; D012160:Retina / Q000032:analysis; D012794:Sialic Acids / Q000032:analysis
D002241:Carbohydrates; D005227:Fatty Acids; D005732:Gangliosides; D012794:Sialic Acids