[The tranquilizing properties of sodium hydroxybutyrate].
Experiments were conducted on rats. It was shown that sodium oxybutyrate depressed the escape response to punishment of the partner and motivated aggression in much lower doses than the defence conditioned reflex and unmotivated aggression, prevented negative consequences of fear and rage reactions; it also normalized conditioned reflexes in neurotic rats, this pointing to its marked tranquillizing action.
D000374:Aggression / Q000187:drug effects; D000818:Animals; D001535:Benactyzine / Q000494:pharmacology; D002415:Cats; D002707:Chlordiazepoxide / Q000494:pharmacology; D003214:Conditioning, Classical / Q000187:drug effects; D003975:Diazepam / Q000494:pharmacology; D004924:Escape Reaction / Q000187:drug effects; D005239:Fear / Q000187:drug effects; D005260:Female; D006801:Humans; D006885:Hydroxybutyrates / Q000494:pharmacology*; D008297:Male; D009497:Neurotic Disorders / Q000188:drug therapy; D011889:Rage / Q000187:drug effects; D051381:Rats; D014149:Tranquilizing Agents
D006885:Hydroxybutyrates; D014149:Tranquilizing Agents; D001535:Benactyzine; D002707:Chlordiazepoxide; D003975:Diazepam
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