ALPHA-Amylase activity in sweat and serum of patients with cystic fibrosis of the pancreas.
The hypothesis by Doggett and Harrison, according to which alpha-amylase is the pathogenic factor of the exocrinopathy in cystic fibrosis (C.F.), is investigated. No elevation of alpha-amylase in sweat and serum of C.F. patients, as compared with controls of similar age, is observed. It is concluded that the "C.F. factor" cannot be identified with alpha-amylase.
D000293:Adolescent; D000681:Amylases / Q000032:analysis* / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000201:enzymology*; D006801:Humans; D013542:Sweat / Q000201:enzymology*
D000681:Amylases