Assignment of the structural gene for human beta glucuronidase to chromosome 7 and tetrameric association of subunits in the enzyme molecule.
The structural locus for human beta glucuronidase is assigned to chromosome 7, a localization based upon concordant segregation of the expression of the human enzyme and the presence of human chromosome 7 in somatic cell hybrid clones derived independently from fusions of different human and mouse cells. Hybrid clones containing only human chromosome 7 are included in this study. Electrophoresis of beta glucuronidase also has revealed that human beta glucuronidase has a tetrametric structure.
D000818:Animals; D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X; D004588:Electrophoresis, Cellulose Acetate; D005796:Genes; D005966:Glucuronidase / Q000378:metabolism*; D006801:Humans; D006822:Hybrid Cells; D007621:Karyotyping; D051379:Mice; D013045:Species Specificity
D005966:Glucuronidase