Trans-unsaturated fatty acids in human skin surface lipids.
Methyl esters of the fatty acids obtained by saponification of human skin surface lipids were subjected to thin-layer chromatography on silica gel-silver nitrate revealing the presence of trans-monounsaturated components constituting approximately 0.3% of the total fatty acids. The positions of unsaturation in the 18-carbon trans-unsaturated acids in 2 subjects resembled those present in the corresponding acids from margarine, although this was not a component of the diet of one of the subjects. Dietary origin is possible for these components, which could also arise from bacterial action in the pilosebaceous follicle.
D002079:Butter; D002855:Chromatography, Thin Layer; D005231:Fatty Acids, Unsaturated / Q000302:isolation & purification*; D006801:Humans; D007536:Isomerism; D008055:Lipids / Q000032:analysis*; D008297:Male; D008383:Margarine; D012867:Skin / Q000032:analysis*
D005231:Fatty Acids, Unsaturated; D008055:Lipids; D002079:Butter; D008383:Margarine