[Alteration of the phospholipid composition and functional state of skeletal muscle fiber mitochondria during muscular activity and rest].
An intensive or prolonged muscular activity causes a decrease in mitochondrial phospholipid content (at the expence of phosphatidylcholine and phosphatidylethanolamine fractions) an augmented turnover of phosphate groups, a decrease of the optical density in mitochondria and the P/O ratio (at the expence of lowering of deltaP). During the recovery period, the content of phospholipids gradually restores: first phosphatidylethanolamine, and then phosphatidylcholine, a temporary increase in the amounts of polyglycerolphosphatide and acid phospholipids proceding. The augmentation of optical density of mitochondria and of P/O ratio over the inintial level coincides in time with the increase in acid phospholipid content. The enrichment of the animals diet with linoleic acid and methionine diminsihes biochemical changes caused by muscular activity in mitochondria to accelerate the normalization.
D000818:Animals; D008931:Mitochondria, Muscle / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D010743:Phospholipids / Q000378:metabolism*; D005082:Physical Exertion; D051381:Rats
D010743:Phospholipids
Izmeneniia fosfolipidnogo sostava i funktsional'nogo sostoianiia mitokhondriĭ skeletnykh myshechnykh volokon pri myshechnoĭ deiatel'nosti i v periode otdykha