Pharmacy, pharmaceutics and modern drug delivery.
Recent developments in the area of drug delivery are reviewed. Controlled delivery of drug substances (including controlled-release oral products, the Folkman-Long silastic device and membrane-medicated delivery systems) are discussed. The prodrug approach is illustrated by discussion of the esterification of epinephrine and the production of the dihydro form of 2-PAM (pro-2-PAM). It is suggested that the pharmacist study the release pattern of drug devices and the pharmaceutics of prodrugs in order to maintain his responsibility as the expert on drugs.
D002626:Chemistry, Pharmaceutical; D003692:Delayed-Action Preparations; D004304:Dosage Forms; D004358:Drug Therapy; D004837:Epinephrine / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D011726:Pyridinium Compounds / Q000008:administration & dosage / Q000627:therapeutic use; D013997:Time Factors
D003692:Delayed-Action Preparations; D004304:Dosage Forms; D011726:Pyridinium Compounds; D004837:Epinephrine