title: Effects of ancestral X irradiation followed by random mating on body weight of rats.
abstract: Effects of nine generations of 450r per generation of ancestral spermatogonial X irradiation of inbred rats on body weight were examined. After six generations of random mating (avoiding inbreeding) following the termination of irradiation, descendants of irradiated males (R) were significantly lighter than their controls (C) at 3 and 6 weeks, but not at 10 weeks of age. However, differences in growth between R and C populations were small. Among-litter and within-litter variance estimates were generally larger in the R lines than in the C lines, suggesting that selection responses would be greater in R than in C lines. In conjunction with previous evidence--obtained during the irradiation phase of the experiment--this suggested that more rapid response to selection for 6-week body weight, in particular, might accrue in the R lines.
mesh_terms: D000818:Animals; D001835:Body Weight; D008297:Male; D008433:Mathematics; D051381:Rats; D011919:Rats, Inbred Strains; D012641:Selection, Genetic / Q000528:radiation effects*; D013093:Spermatogonia / Q000528:radiation effects; D014965:X-Rays