Circular DNA and cardiolipin in hydrogenosomes, microbody-like organelles of trichomonads.
Circular molecules of DNA approximately 3 mum in length were revealed by electron microscopy in deproteinized extracts prepared from purified hydrogenosomal fraction of a protozoan Tritrichomonae foetus. This fraction contained also cardiolipin amounting to approximately 14.4% of its total phospholipids, as detected by thin-layer chromatography and quantitative phosphorus measurement. These characteristics extend a number of biochemical properties of hydrogenosome shared also by mitochondria and by prokaryotic cells.
D002308:Cardiolipins / Q000302:isolation & purification*; D004270:DNA, Circular / Q000302:isolation & purification*; D009940:Organoids / Q000032:analysis* / Q000648:ultrastructure; D014318:Tritrichomonas / Q000032:analysis / Q000648:ultrastructure*
D002308:Cardiolipins; D004270:DNA, Circular