Cervical canal aspiration smears in hormonal cytodiagnosis.
On the basis of 200 women with functional ovarian disturbances analysed, it has been found that though cervical canal aspiration smears along cannot serve in hormonal diagnosis they can be valuable when estimated together with vaginal smears, particularly in the cases with the Intermediate Cell Complex. In oestrogen deficiency cytologic indices of CCAS are close to those of VS, cervical mucus is opaque, gray, homogenous and abundant in leukocytes and histiocytes; and glandular cells, both endometrial and endocervical, are hypothrophic. In oestrogen and androgen stimulation, high M.V., S.C.I., and E.I. and low N.I., C.I., F.I. and C., abundant, transparent, polychromatic and membranaceous cervical mucus scant in leukocytes and histiocytes; and typical oestrogenic appearance of the endometrial and endocervical cells are observed in CCAS, as compared to VS, where high C. and leukopenia are typical. In dried smears, arborization of the cervical mucus is usually seen in these cases. In luteal stimulation, M.V., S.C.I. K.I., and E.I. are slightly elevated, N.I., C.I., F.I., and C. are lower, cervical mucus is opaque, gray, and homogenous, abundant in leukocytes and scant in histiocytes, endometrial glandular cells are secretory, and endocervical cells are of luteal type in CCAS in comparison to VS. Some residual arborization phenomenon is frequenyc present in dried mucus. These preliminary results require further studies.
D000728:Androgens / Q000378:metabolism; D004967:Estrogens / Q000378:metabolism; D005260:Female; D006801:Humans; D010049:Ovarian Diseases / Q000378:metabolism / Q000473:pathology*; D002577:Uterine Cervical Diseases / Q000378:metabolism / Q000473:pathology*; D014626:Vaginal Smears / Q000379:methods*
D000728:Androgens; D004967:Estrogens