[Renal and circulatory function under ketamine anesthesia. An experimental study on animals (author's transl)].
Cardiac output, glomerular filtration rate, stroke volume, heart rate, and urinary output were determined in 10 mongrel dogs. Under the conditions of the experiment it was observed that in contrast to man cardiac and renal output as well as stroke volume declined significantly. Heart rate showed no significant change. With diminished urinary output a differential excretion of individual electrolytes was noted. To carry the results of these experiments over to humans is, in the author's view, not warranted unreservedly.
D000771:Anesthesia, Intravenous; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects*; D004285:Dogs; D004837:Epinephrine / Q000378:metabolism; D005919:Glomerular Filtration Rate; D006339:Heart Rate / Q000187:drug effects; D006706:Homeostasis / Q000187:drug effects; D006801:Humans; D007649:Ketamine / Q000494:pharmacology*; D007668:Kidney / Q000098:blood supply / Q000187:drug effects*; D012039:Regional Blood Flow / Q000187:drug effects; D012964:Sodium / Q000652:urine; D013045:Species Specificity; D014556:Urine / Q000378:metabolism
D007649:Ketamine; D012964:Sodium; D004837:Epinephrine
Nieren- und Kreislauffunktion unter Ketaminnarkose. Eine tierexperimentelle Studie