Gynecologic specimen analysis by multiangle light scattering in a flow system.
A flow-system instrument is described in which the laser light scattered by a mammalian cell is sampled simultaneously at up to 32 angles between 0 degrees and 21 degrees from the laser beam axis as the cell passes through the beam. The scatter pattern for each cell is stored by a computer for later analysis. Various data-processing techniques are discussed. Results of preliminary application of the instrument to the analysis of normal and abnormal gynecologic specimens are presented.
D001322:Autoanalysis; D002467:Cell Nucleus / Q000648:ultrastructure; D002584:Cervix Uteri / Q000166:cytology*; D003581:Cytodiagnosis; D005260:Female; D006801:Humans; D007834:Lasers; D007962:Leukocytes / Q000166:cytology / Q000648:ultrastructure; D008027:Light; D008853:Microscopy / Q000295:instrumentation / Q000379:methods; D012542:Scattering, Radiation; D014621:Vagina / Q000166:cytology*; D014626:Vaginal Smears