title: Natural resistance of an African rodent Praomys (Mastomys) natalensis to rabies infection.
abstract: Praomys (Mastomys) natalensis, the multimammate mouse, proved resistant to the intracerebral and peripheral infection with rabies virus of serotype 1, which is found world-wide. It is, however, fully susceptible to the other serotypes of this virus group, which to-date have only been found on the African continent. Resistance develops between the third and twenty-first day after birth. In the brain of the resistant animal the inoculated virus multiplies to a low degree and the animal does not develop a fatal disease.
mesh_terms: D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000917:Antibody Formation; D001902:Botswana; D001921:Brain / Q000382:microbiology; D007109:Immunity; D051379:Mice; D011818:Rabies / Q000276:immunology*; D011820:Rabies virus / Q000254:growth & development / Q000472:pathogenicity; D012377:Rodentia / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral