Use of substrate-coated barium sulfate tablets in the evaluation of digestive enzyme deficiency.
In vitro and in vivo studies determined the effect of digestive enzymes on substrate-coated barium sulfate tablets. Fragmentation of the barium tablet core was detected radiographically after enzymatic digestion of the substrate material occurred. Preliminary studies in humans suggest that such tablets may be used in the diagnosis of pancreatic exocrine insufficiency.
D000328:Adult; D000818:Animals; D001466:Barium Sulfate; D002766:Cholecystokinin / Q000494:pharmacology; D004285:Dogs; D004798:Enzymes / Q000172:deficiency*; D006801:Humans; D008297:Male; D010168:Palmitates; D010182:Pancreatic Diseases / Q000000981:diagnostic imaging; D010865:Pilot Projects; D010940:Plant Proteins; D011859:Radiography; D013213:Starch; D013268:Stimulation, Chemical; D013608:Tablets, Enteric-Coated
D004798:Enzymes; D010168:Palmitates; D010940:Plant Proteins; D013608:Tablets, Enteric-Coated; D001466:Barium Sulfate; D013213:Starch; D002766:Cholecystokinin