[The effect of hydrocortisone and insulin on ribonucleic acid synthesis in the nuclei and cytoplasm of sexually mature male rat liver cells].
Prolonged administration to male sexually-mature rats weighing 180-200 g of hydrocortisone, protamine-zinc-insulin enhanced considerably the synthesis of DNA-like RNA, precursor of ribosomal RNA in the nuclei and ribosomal RNA in the cytoplasm of the liver; this increase was even more pronounced after the administration of both hormones. The data obtained were in favour of the participation of DNA-like RNA, precursor of ribosomal RNA of the nuclei and ribosomal RNA of the cytoplasm of the liver of male sexually-mature rats in the synthesis of transaminases of their liver.
D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism; D006854:Hydrocortisone / Q000494:pharmacology*; D049528:Insulin, Long-Acting / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism / Q000648:ultrastructure; D008297:Male; D012313:RNA / Q000096:biosynthesis*; D012335:RNA, Ribosomal / Q000096:biosynthesis; D051381:Rats
D049528:Insulin, Long-Acting; D012335:RNA, Ribosomal; D012313:RNA; D006854:Hydrocortisone
Vliianie gidrokortizona i insulina na sintez ribonukleinovykh kislot v iadrakh i tsitoplazme kletok pecheni polovozrelykh krys-samtsov