The preparation of 5-spiro-7'-(bicyclo (4.1.0.) heptane)barbituric acid.
The 7,7-diethoxycarbonylnorcarane (III), obtained by a catalytic decomposition of diethyldiazomalonate (I a) in cyclohexene, was condensed with urea to give the 5-spiro-7'-(bicyclo(4.1.0.)heptane)barbituric acid (IV).
D001463:Barbiturates / Q000138:chemical synthesis*; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis; D002384:Catalysis; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013141:Spiro Compounds / Q000138:chemical synthesis
D001463:Barbiturates; D001643:Bridged Bicyclo Compounds; D007202:Indicators and Reagents; D013141:Spiro Compounds