title: Genetic structure of the replication origin of bacteriophage lambda.
abstract: A fragment of bacteriophage lambda DNA produced by the restriction endonuclease Eco RI and extending from the immunity region to a point inside gene O is found to have a fully functional origin of replication. Seven ori- mutations of lambda cluster in a small region just to the left of the Eco RI cleavage site which defines the right end of this fragment. These mutations lie within gene O.
mesh_terms: D002874:Chromosome Mapping; D003090:Coliphages / Q000235:genetics*; D004261:DNA Replication; D005796:Genes; D005809:Genes, Regulator; D005814:Genes, Viral; D009154:Mutation; D012367:RNA, Viral / Q000096:biosynthesis; D014158:Transcription, Genetic; D014779:Virus Replication
chemical_list: D012367:RNA, Viral