Continuation of mitosis after selective laser microbeam destruction of the centriolar region.
The centriole regions of prophase PTK2 cells were irradiated with a laser microbeam. Cells continued through mitosis normally. Ultrastructural analysis revealed either an absence of centrioles or severely damaged centrioles at the irradiated poles. Microtubules appeared to focus into pericentriolar cloud material.
D000705:Anaphase; D002460:Cell Line; D007834:Lasers; D008870:Microtubules / Q000648:ultrastructure; D008938:Mitosis; D009940:Organoids / Q000502:physiology / Q000528:radiation effects / Q000648:ultrastructure; D011418:Prophase