Rate-dependent effect of amphetamine in rats: extension to between-subjects effect.
Following either variable-interval or fixed-interval training. 20 rats received both 0.5 and 2.0 mg/kg of amphetamine. For both schedules, amphetamine decrease response rates of high-rate subjects and increased those of low-rate subjects. Within-subject analysis of fixed-interval rates revealed the same rate-dependent effect. It is suggested that the between-subject and within-subject effects may have the same basis.
D000818:Animals; D003216:Conditioning, Operant / Q000187:drug effects*; D003913:Dextroamphetamine / Q000494:pharmacology*; D008297:Male; D051381:Rats; D012055:Reinforcement Schedule
D003913:Dextroamphetamine