[Decrease of intestinal absorption of 47-calcium in chronic alcoholism].
Intestinal 47-calcium absorption has been studied in 34 chronic alcoholics, 17 of whom were cirrhotics (group A) and 17 non-cirrhotics (group B). These patients were compared with 44 normal subjects (group C). In group C, the 47Ca 2 h plasma % of the dose showed a significant negative correlation to the total body weight (p less than 0.001) and a positive correlation with the serum albumin (p less than 0.05). The mean intestinal absorption of 47Ca expressed as 2 h plasma % of the dose multiplied by total body weight was 131 +/- SD 52 in group A and 136 +/- SD 71 in group B. These two means are significantly low (p less than 0.001 and p less than 0.002 respectively) in relation to that found in group C (168 +/- SD 32). These results suggest that intestinal calcium absorption is diminished in chronic alcoholism even in the absence of hepatic cirrhosis.
D000437:Alcoholism / Q000150:complications*; D002118:Calcium / Q000378:metabolism*; D002128:Calcium Metabolism Disorders / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D002132:Calcium Radioisotopes / Q000097:blood; D006801:Humans; D007408:Intestinal Absorption; D008104:Liver Cirrhosis, Alcoholic / Q000097:blood / Q000378:metabolism
D002132:Calcium Radioisotopes; D002118:Calcium
Diminution de l'absorption intestinale de 47-calcium dans l'alcoolisme chronique.