title: The pulmonary absorption-excretion volume effect.
abstract: An in-vitro experiment demonstrated the concentration effect of N2O (3% versus 75%) during elimination and during uptake. Other pulmonary absorption-excretion phenomena also occur simultaneously, as paired events during uptake and then during elimination:diffusion hyperoxia and diffusion anoxia; alveolar concentration of CO2, and alveolar dilution of CO2. These clinical phenomena, as well as the second gas effect, are all related, and the pulmonary absorption-excretion volume is found to depend in part on the type of ventilation:volume controlled, pressure controlled, or spontaneous respiration.
mesh_terms: D000769:Anesthesia, Inhalation; D004305:Dose-Response Relationship, Drug; D008168:Lung / Q000378:metabolism*; D009609:Nitrous Oxide / Q000378:metabolism*; D012123:Pulmonary Ventilation; D012119:Respiration
chemical_list: D009609:Nitrous Oxide