Comparative toxicity of trivalent and hexavalent chromium to rabbits. II. Morphological changes in some organs.
Toxicity of trivalent and hexavalent chromium compounds was investigated in experimental rabbits to ascertain health hazards among industrial workers of miners occupationally exposed to such chemicals. Brain, kidney and myocardium showed a tendency to accumulate chromium irrespective of its valency state; the morphological changes were more marked in animals exposed to hexavalent chromium. However, no definite co-relation could be observed between the concentration of the metal and the degree of histological changes in these organs.
D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects / Q000473:pathology; D002857:Chromium / Q000633:toxicity*; D006321:Heart / Q000187:drug effects; D007668:Kidney / Q000187:drug effects / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D009928:Organ Specificity; D011817:Rabbits; D013329:Structure-Activity Relationship
D002857:Chromium