Hashimoto's thyroiditis and breast cancer.
The question of a possible association between Hashimoto's thyroiditis and breast cancer was evaluated in (1) an autopsy series and (2) a follow-up of a cohort of patients with Hashimoto's thyroiditis at the Mayo Clinic. In the autopsy study, 174 subjects with histologic diagnosis of Hashimoto's thyroiditis were matched with a control group. There was no significant difference in the frequency of a history of breast cancer in the two groups. In the cohort of Olmsted County residents with a clinical or histologic diagnosis of Hashimoto's thyroiditis for whom there was a substantial period of follow-up, no excess frequency of breast cancer was note. These results contrast with those of a recent study reporting that Japanese women with Hashimoto's thyroiditis were a high risk group for breast cancer.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001344:Autopsy; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000473:pathology; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D008910:Minnesota; D012306:Risk; D013961:Thyroid Gland / Q000473:pathology; D013967:Thyroiditis, Autoimmune / Q000150:complications* / Q000473:pathology