Plasma concentrations of 13,14-dihydro-15-keto-prostaglandin F during pregnancy in sheep.
A specific and sensitive radioimmunoassay is decribed for 13,14-dihydro-15-keto-prostaglandin F in ovine plasma. Using this assay it has been shown that, in sheep, jugular venous 13,14-dihydro-15-keto-prostaglandin F concentrations increase at parturition and correlate well with concentrations of prostaglandin F in the utero-ovarian vein. It is suggested that uterine prostaglandin F production under these conditions may be assessed by measuring peripheral venous 13,14-dihydro-15-keto-prostaglandin F, thereby avoiding the need for chronic utero-ovarian venous catheters.
D000818:Animals; D005260:Female; D011247:Pregnancy; D011270:Pregnancy, Animal; D011458:Prostaglandins E / Q000097:blood; D011460:Prostaglandins F / Q000097:blood*; D011863:Radioimmunoassay; D012756:Sheep / Q000097:blood*; D013048:Specimen Handling
D011458:Prostaglandins E; D011460:Prostaglandins F