title: Monitoring of nonspecific cell-mediated immunity in cancer patients. I. Frequent dissociation between the responses of skin tests to recall antigens and in vitro lymphocyte transformation.
abstract: No correlation was found between in vivo delayed hypersensitivity responses in cancer patients and in vitro lymphocyte transformation by mitogens or antigens, even when the same antigen [purified protein derivative of tuberculin (PPD)] was used for both the in vivo and in vitro testing. However, there was a good correlation between the in vitro lymphocyte transformation tests with PPD and with the mitogens phytohemagglutinin and pokeweed mitogen.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed; D007111:Immunity, Cellular; D037102:Lectins / Q000276:immunology; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D008934:Mitogens / Q000276:immunology; D009369:Neoplasms / Q000276:immunology*; D012882:Skin Tests; D014373:Tuberculin / Q000276:immunology
chemical_list: D037102:Lectins; D008934:Mitogens; D014373:Tuberculin