Traumatic hyphaema treated with the antifibrinolytic drug tranexamic acid.
During the year 1975 (Jan. 1st-Dec. 31st) 72 patients, consecutively admitted to the eye department of Arhus Kommunehospital with traumatic hyphaema, were treated with the antifibrinolytic drug tranexamic acid. Secondary haemorrhage occurred in one case. This incidence of secondary haemorrhage (1.4%) seems to be the lowest on record. A group of patients from the period 1965-1968, treated identically with the exception of the tranexamic acid, were selected for comparison. This group of 135 patients included 9 cases (6.7%) with a secondary haemorrhage. The difference between these two groups is statistically significant (P less than 0.05).
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D005131:Eye Injuries / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D006988:Hyphema / Q000150:complications / Q000188:drug therapy*; D007223:Infant; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D014148:Tranexamic Acid / Q000627:therapeutic use*
D003509:Cyclohexanecarboxylic Acids; D014148:Tranexamic Acid