Hemoglobin Jackson, alpha 127 (H10) Lys replaced by Asn.
A new hemoglobin mutant was detected as a fast-moving variant on cellulose acetate electrophoresis at pH 8.4. The mutation is in the alpha-chain at position 127, where lysine is substituted by asparagine. This is an external residue, and mutation at this site does not lead to any altered physiologic function of the hemoglobin.
D000328:Adult; D000596:Amino Acids / Q000032:analysis; D005260:Female; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans
D000596:Amino Acids; D006455:Hemoglobins, Abnormal