A new diagnostic test for pancreatic disorders by examination of parotid saliva.
The parotid saliva test was performed in 146 subjects, including 48 patients with pancreatic disorders, 82 with nonpancreatic disorders and 16 healthy persons. The following results were obtained: 1. The salivary output as well as the maximum bicarbonate concentration and amylase content in the parotid saliva of patients with pancreatic disorders were significantly less than those of patients with nonpancreatic disorders. 2. An abnormal saliva test was found in 83.3% of the patients with the pancreatic disorders. 3. Comparison was made of the parotid saliva test with the pancreozyminsecretin test in regard to diagnostic reliability in 44 subjects, including 22 with pancreatic disorders and 22 with nonpancreatic disorders. The data indicated that, in this series, an abnormal parotid saliva test was 88.6% accurate in diagnosing pancreatic disorders, whereas positive pancreozymin-secretin was only 65.9%.
D000681:Amylases / Q000032:analysis*; D001639:Bicarbonates / Q000032:analysis*; D002766:Cholecystokinin / Q000032:analysis; D004796:Clinical Enzyme Tests; D006801:Humans; D008722:Methods; D010182:Pancreatic Diseases / Q000175:diagnosis*; D010306:Parotid Gland / Q000378:metabolism*; D012463:Saliva / Q000032:analysis*; D012633:Secretin / Q000032:analysis; D012636:Secretory Rate
D001639:Bicarbonates; D012633:Secretin; D002766:Cholecystokinin; D000681:Amylases