Disseminated pulmonary blastomycosis in an immunosuppressed patient. Diagnosis by fiberoptic bronchoscopy.
A 73-year-old man with malignant lymphoma who was undergoing treatment with systemic chemotherapy presented with an acute, febrile illness associated with cough and sputum production. The patient developed bilateral, diffuse, pulmonary interstitial infiltrates with rapidly progressive respiratory insufficiency. The diagnosis was made by demonstrating Blastomyces dermatitidis in bronchial brush and transbronchial lung biopsy specimens obtained through fiberoptic bronchoscopy.
D000368:Aged; D001759:Blastomycosis / Q000150:complications / Q000175:diagnosis*; D001999:Bronchoscopy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008172:Lung Diseases, Fungal / Q000150:complications / Q000175:diagnosis*; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000188:drug therapy; D008297:Male
D007166:Immunosuppressive Agents