Familial risk and cancer control.
An intensive study of the family history of cancer in 4,515 patients screened consecutively by a multiphasic mobile cancer detection unit showed, after age correction, that cancer had developed in 8.9% of the probands when there was one cancer in a single first-degree relative, 16.2% had cancer with two family members affected, and 27.4% had cancer when three or more family members had been affected. This constituted a significant correlation between family and personal histories of cancer in these patients. Extrapolation to the United States population with cancer-control implications are given.
D000367:Age Factors; D003241:Consanguinity; D005191:Family Characteristics; D006801:Humans; D009098:Multiphasic Screening; D009329:Nebraska; D009369:Neoplasms / Q000453:epidemiology / Q000235:genetics* / Q000517:prevention & control; D012306:Risk; D012959:Socioeconomic Factors; D014481:United States