Some chemical and pharmacological properties of 2-methyl-5H(1)benzopyrano(2,3-b) pyrid-5-one.
The synthesis of the mentioned compound, their N-oxide and N-oxide 7-nitro derivative is described. The reactivity of the CO, N-oxide groups and heterocyclic N atom was investigated. Of the obtained new compounds 2-methyl-5-(3'-dimethyl-aminopropylidene)-5H-(1)benzopyrano [2,3-b] pyridine 4 acts on central nervous system.
D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D001578:Benzopyrans / Q000138:chemical synthesis / Q000494:pharmacology / Q000633:toxicity; D001831:Body Temperature / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D003864:Depression, Chemical; D004357:Drug Synergism; D006591:Hexobarbital / Q000494:pharmacology; D006801:Humans; D007928:Lethal Dose 50; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D012110:Reserpine / Q000494:pharmacology; D012890:Sleep / Q000187:drug effects; D013239:Stereotyped Behavior / Q000187:drug effects
D001578:Benzopyrans; D012110:Reserpine; D006591:Hexobarbital; D000661:Amphetamine