title: Antileukemic and other constituents of Tithonia tagitiflora Desf.
abstract: Phytochemical investigation of Tithonia tagitiflora has led to isolation of six new germacranolides, tagitinins A, B, C, D, E, AND F, beta-sitosterol, and its beta-D-glucoside. Among these, tagitinin F possesses  antileukemic activity.
mesh_terms: D000818:Animals; D007783:Lactones / Q000032:analysis / Q000627:therapeutic use*; D007942:Leukemia, Experimental / Q000188:drug therapy; D051379:Mice; D010936:Plant Extracts / Q000032:analysis / Q000627:therapeutic use; D012717:Sesquiterpenes / Q000032:analysis / Q000627:therapeutic use*; D012855:Sitosterols / Q000302:isolation & purification / Q000627:therapeutic use
chemical_list: D007783:Lactones; D010936:Plant Extracts; D012717:Sesquiterpenes; D012855:Sitosterols; C012565:tagitinin