Determing the pulmonary excretion rate of carbon monoxide in newborn infants.
A simplified technique was devised for measurement carbon monoxide excretion rates in newborn infants. Determinations can be performed quickly and repetitively in a noninvasive manner, with a sensitivity sufficient for use even on small preterm infants. Resolution of the method is +/- 4.3 mul/h (SD); however, variations in infant respiration rate may cause much greater changes in actual excretion rate. Preliminary results with five full-term newborn agree to within 15% of previously reported data. The system will be used extensively in ongoing studies involving total bilirubin production as a function of gestational age.
D001663:Bilirubin / Q000032:analysis; D002248:Carbon Monoxide / Q000032:analysis / Q000378:metabolism*; D002263:Carboxyhemoglobin / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D012119:Respiration; D012129:Respiratory Function Tests / Q000379:methods
D002248:Carbon Monoxide; D002263:Carboxyhemoglobin; D001663:Bilirubin