title: The degree of bone mineralization in hyperthyroidism estimated from the phosphorus to hydroxyproline ratio in bone.
abstract: The proportion between mineral and collagen in bone tissue, "the degree of mineralization", can be evaluated from the phosphorus to hydroxyproline ratio (P/Hypro ratio), determined in bone biopsies. The ratio was measured in 27 unselected hyperthyroid patients. No significant correlation was found between the P/Hypro ratio and the age of the patient, the duration of the disease or the value of serum thyroxine. The mean value of the P/Hypro ratio for the group studied was not significantly different from the normal mean. The results of the study indicate a normal degree of mineralization in the bone of patients with hyperthyroidism.
mesh_terms: D000328:Adult; D000368:Aged; D001842:Bone and Bones / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D006909:Hydroxyproline / Q000378:metabolism*; D006980:Hyperthyroidism / Q000378:metabolism* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010758:Phosphorus / Q000378:metabolism*
chemical_list: D010758:Phosphorus; D006909:Hydroxyproline