title: A possible subgroup of the schizophrenic syndrome and implications for treatment.
abstract: Supported by extensive clinical data of three generations, the hypothesis is advanced that Minimal Brain Dysfunction is the major etiologic and pathogenic factor for one subgroup of adult schizophrenics. Genetic factors apparently play the main but not exclusive role. Pathogenic as well as diagnostic, therapeutic, prognostic, and preventive aspects are discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications* / Q000235:genetics; D003975:Diazepam / Q000627:therapeutic use; D004292:Dominance, Cerebral; D004410:Dyslexia / Q000150:complications; D005260:Female; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D007175:Impulsive Behavior; D007859:Learning Disabilities / Q000150:complications; D008297:Male; D008774:Methylphenidate / Q000627:therapeutic use; D008875:Middle Aged; D010672:Phenytoin / Q000627:therapeutic use; D011575:Psychoanalytic Therapy; D012559:Schizophrenia / Q000188:drug therapy / Q000209:etiology / Q000235:genetics / Q000628:therapy*; D012649:Self Concept; D013028:Space Perception
chemical_list: D008774:Methylphenidate; D010672:Phenytoin; D006220:Haloperidol; D007099:Imipramine; D003975:Diazepam