[Sephadex G 100- Separation of the mucicrinic and the mucimitiginic factors from an extract of duodenal mucosa (author's transl)].
The mucicrin stimulating the hexosamine gastrointestinal secretion and extracted form porcine duodenum, was concentrated in the zone 7 using sephadex G 100. The molecular weight of 4000-5000 corresponds to this zone. An opposite activity was detected in zone 3. The factor from digestive mucous origin being able to diminish the hexosamine gastric secretion and not influencing the arterial pressure was called mucimitigin. The molecular weight of about 35000 corresponds to this factor.
D000818:Animals; D002850:Chromatography, Gel; D004386:Duodenum; D005752:Gastric Mucins / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism; D005768:Gastrointestinal Hormones / Q000302:isolation & purification* / Q000502:physiology; D006595:Hexosamines / Q000378:metabolism; D006727:Hormone Antagonists / Q000302:isolation & purification*; D007413:Intestinal Mucosa / Q000032:analysis*; D008297:Male; D051381:Rats; D013552:Swine
D005752:Gastric Mucins; D005768:Gastrointestinal Hormones; D006595:Hexosamines; D006727:Hormone Antagonists
Séparation sur séphadex G 100 de facteurs mucicriniques et mucimitiginiques à partir d'un extrait de muqueuse duodénale