Genetic predisposition and stress-induced hypertension.
When chronically exposed to an approach-avoidance conflict, rats with a genetic susceptibility to hypertension showed persisten elevations in systolic blood pressure, but rats with a genetic resistance to hypertension did not. Hence, psychic stress is selectively efficacious in producing hypertensive effects depending on genetic predisposition of the animal.
D000818:Animals; D001794:Blood Pressure; D003216:Conditioning, Operant / Q000502:physiology; D003220:Conflict, Psychological; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000235:genetics*; D008297:Male; D051381:Rats; D013315:Stress, Psychological / Q000502:physiology*