Total and individual kidney function assessment with iodine-123 ortho-iodohippurate.
A simple and reliable method of preparing 123l o-iodohippurate (l-123 OIH) is described. The agent was used to evaluate renal function in 329 patients; its use results in significant dose reduction for those with obstruction, hypertension, or transplant. Images from l-123 OIH provide 2.4 times more detectable photons per mCi administered to the patient than images obtained from l-131 OIH. Diagnoses are expected to be more reliable with l-123 OIH due to the decreased random variation of each data point.
D000328:Adult; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D007465:Iodohippuric Acid; D007674:Kidney Diseases / Q000000981:diagnostic imaging*; D007677:Kidney Function Tests / Q000379:methods; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011877:Radionuclide Imaging
D007457:Iodine Radioisotopes; D007465:Iodohippuric Acid