title: The functional role of intravascular coagulation renal disease.
abstract: There is evidence of intravascular coagulation in accelerated hypertension and pre-eclamptic toxaemia, in all types of nephritis and in the haemolyticuraemia syndrome. The kidneys have a two-fold defence mechanism, namely mesangial cell phagocytosis and endothelial cell fibrinolytic activity. Intravascular coagulation occurs in all those types of shock that result in acute renal failure: more often than not the primary cause is endotoxinaemia.
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000503:physiopathology; D000818:Animals; D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000503:physiopathology*; D004731:Endotoxins / Q000097:blood; D005260:Female; D005342:Fibrinolysis; D006463:Hemolytic-Uremic Syndrome / Q000503:physiopathology; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D007674:Kidney Diseases / Q000097:blood* / Q000209:etiology; D009393:Nephritis / Q000503:physiopathology; D010587:Phagocytosis; D011225:Pre-Eclampsia / Q000503:physiopathology; D011247:Pregnancy; D011817:Rabbits; D051381:Rats; D012769:Shock / Q000503:physiopathology
chemical_list: D004731:Endotoxins