title: Effect of testosterone propionate on the ultrastructure of the preputial gland in the rat.
abstract: Testosterone propionate accelerates the maturation of acinar cells in the preputial gland of female rats. The weight of the preputial gland was increased significantly and the gland contained a large amount of secretory material. Various stages of maturation of acinar cells were observed. In an early stage, cells contained predominantly rough endoplasmic reticulum. In a second stage, lipid accumulated in association with focal areas of smooth endoplasmic reticulum. Membrane-bound dense bodies similar to lysosomes and secondary lysosomes predominated in a late stage. In the final stage, acini fused with a duct, thereby liberating the cells into the ductal lumen. Cell structure then became unrecognizable.
mesh_terms: D000818:Animals; D005260:Female; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D012627:Sebaceous Glands / Q000166:cytology / Q000187:drug effects / Q000648:ultrastructure*; D013268:Stimulation, Chemical; D013739:Testosterone / Q000494:pharmacology*
chemical_list: D013739:Testosterone