title: Isotope angiography: technique, validation and value in the assessment of arterial reconstruction.
abstract: Isotope angiography performed by intravenous injection of technetium 99m pertechnetate has been demonstrated to be of value in the diagnosis and management of a variety of disorders of the large arteries. An improved technique of isotope angiography is described and the technique validated (53 cases) in normal and diseased arteries by correlating it with conventional contrast arteriography and/or operative findings. Peripheral arteries as far distal as the wrist or mid-calf have been accurately visualized and quantitation of isotope arrival times and total isotope activity in different parts of the arterial tree has provided a means of evaluating the hemodynamic significance of stenosing lesions. Thirty-nine arterial reconstructions were studied by this technique. Seven of 27 (26%) clinically patent arterial reconstructions were found to be harboring significant and potentially dangerous imperfections which were clinically unsuspected. Nine of 12 (75%) arterial reconstructions thought clinically to be occluded were demonstrated to be patent, obviating the need for invasive contrast arteriography. Isotope angiography may be used with no risk for the immediate postoperative and long-term evaluation of arterial reconstructions. Only those patients with abnormalities identified on isotope angiography need have conventional contrast arteriography for further delineation of the abnormality so that it may be repaired before it causes failure of the reconstruction.
mesh_terms: D000783:Aneurysm / Q000175:diagnosis / Q000601:surgery; D001157:Arterial Occlusive Diseases / Q000175:diagnosis / Q000601:surgery; D001158:Arteries / Q000601:surgery*; D005069:Evaluation Studies as Topic; D006801:Humans; D011877:Radionuclide Imaging / Q000379:methods*; D013667:Technetium; D013923:Thromboembolism / Q000175:diagnosis / Q000601:surgery; D014652:Vascular Diseases / Q000175:diagnosis / Q000601:surgery*
chemical_list: D013667:Technetium