The effect of hemorrhagic shock on disseminated intravascular coagulation.
Experiments tend to confirm the hypothesis that a thromboplastic substance in the blood stream causes little DIC if blood flow is normal. However, if the same quantity of thromboplastic material is present in a slow capillary flow, it will produce DIC and possible death, with a marked clotting defect.
D000818:Animals; D001772:Blood Cell Count; D001792:Blood Platelets / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D011817:Rabbits; D012771:Shock, Hemorrhagic / Q000150:complications*; D013917:Thrombin / Q000494:pharmacology
D013917:Thrombin