Are there 2 cholinergic thermoregulatory centres in rats?
An attempt was made to replicate the conflicting previous reports of hypo- and hyperthermic effects of intrahypothalamically administered carbachol. Despite using the same coordinates, injection parameters, and strain of rats reported by others, only hypothermia was conclusively demonstrated. It was concluded that the cholinergic system mediates heat loss mechanisms in rats.
D000818:Animals; D001833:Body Temperature Regulation / Q000187:drug effects*; D002217:Carbachol / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D008297:Male; D051381:Rats / Q000502:physiology*
D002217:Carbachol