Iron dynamics in the ruminant.
We have compared the plasma clearance rate of radioactive iron in cows both as ferric chloride and as iron specifically bound to transferrin. We have also repeated the transfusion experiment of Dern et al. (Dern, R.J., Monti A. and Glynn, M.F. (1963) J. Lab. Clin. Med. 61,280-291) using goats. The results show that neither non-specificity bound iron (Bates, F.W. and Schlabach, M.R. (1973) J. Biol. Chem. 248, 3228-3232) nor the iron bound to the two different sites in transferrin (Awai, M., Chipman, B. and Brown, E.B. (1975) J. Lab. Clin. Med. 85,769-784) can be identified as distinguishable iron pools by this technique.
D000818:Animals; D001803:Blood Transfusion; D002417:Cattle; D005260:Female; D006041:Goats; D006207:Half-Life; D007501:Iron / Q000097:blood*; D007700:Kinetics; D011485:Protein Binding; D014168:Transferrin / Q000378:metabolism*
D014168:Transferrin; D007501:Iron