Vaccination of lambs against infection with Taenia ovis using antigens collected during short-term in vitro incubation of activated T. ovis oncospheres.
Activated oncospheres of Taenia ovis were incubated for 24 h or 48 h at 37-5 degress C in Medium 858 alone or in Medium 858 enriched with 20% lamb serum or foetal calf serum. Antigens contained in the supernatant medium from these incubations were concentrated, emulsified in Freund's incomplete adjuvant and injected intramuscularly into lambs. These lambs developed a very high level of immunity to subsequent challenge infection with T. ovis eggs.
D000818:Animals; D000941:Antigens; D012756:Sheep; D012757:Sheep Diseases / Q000517:prevention & control*; D013621:Taenia / Q000276:immunology*; D013622:Taeniasis / Q000517:prevention & control / Q000662:veterinary*; D014611:Vaccination; D014612:Vaccines
D000941:Antigens; D014612:Vaccines