Migration of plasticiser from haemodialysis blood tubing.
Di-2-ethylhexyl phthalate (DEHP) was found to migrate from polyvinyl chloride (PVC) blood tubing into human blood during both in vivo and in vitro haemodialysis. DEHP blood level increased during in vivo dialysis but decreased again toward the end of a six hour dialysis period. During in vitro haemodialysis of outdated human blood DEHP accumulated up to 5580 ppb. Although toxic effects have not yet been observed, we believe plastic tubing that does not contain extractable materials should be developed.
D004051:Diethylhexyl Phthalate / Q000097:blood*; D006801:Humans; D007688:Kidneys, Artificial; D010795:Phthalic Acids / Q000097:blood*; D011143:Polyvinyl Chloride
D010795:Phthalic Acids; D011143:Polyvinyl Chloride; D004051:Diethylhexyl Phthalate