Effects of prenatal alcohol consumption on open-field behaviour and alcohol preference in rats.
Throughout gestation pregnant Wistar rats consumed a liquid diet containing sustagen and ethanol. Control mothers were fed on lab chow. Subsequently, the offspring of the ethanol-fed mothers displayed significantly greater activity (ambulation and rearing) in an open-field test. Further, pups whose mothers were exposed to ethanol consumed significantly more ethanol in a preference test, compared to control offspring.
D000428:Alcohol Drinking; D000818:Animals; D004644:Emotions / Q000187:drug effects; D000431:Ethanol / Q000494:pharmacology*; D005106:Exploratory Behavior / Q000187:drug effects*; D005260:Female; D005333:Fetus / Q000187:drug effects*; D008431:Maternal-Fetal Exchange; D009043:Motor Activity / Q000187:drug effects; D011247:Pregnancy; D051381:Rats
D000431:Ethanol