Vitamin K-responsive coagulopathy in Henoch-Schölein purpura.
Henoch-Schönlein purpura is classically described as a systemic vasculitis without known platelet or clotting abnormality. A 15-year-old boy with Henoch-Schönlein purpura experienced a major hemorrhagic diathesis that was responsive to parenterally administered vitamin K. We believe that the gastrointestinal vasculitis prevented the absorption of available vitamin K necessary for the synthesis of clotting factors. Early treatment with parenteral vitamin K in similar cases should be considered.
D000293:Adolescent; D001778:Blood Coagulation Disorders / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications*; D008297:Male; D014812:Vitamin K / Q000627:therapeutic use*
D014812:Vitamin K