title: [Cerebral circulation (measured by isotopes) and acid-base equilibrium of the cerebrospinal fluid during migraine].
abstract: In migraine patients a considerable metabolic disturbance characterised by a decrease in bicarbonate and an increase in lactate was demonstrated during the migrainous state. Measurements of the cerebral circulation were taken by means of radioactive isotope and showed a distinct decrease in blood supply to the entire brain during the migraine attack. Following forced hyperventilation during the attack-free interval a pathological reactivity with decreased blood flow was found in the hemisphere which had been indicated as the usual site of the migrainous pain.
mesh_terms: D000136:Acid-Base Equilibrium; D001639:Bicarbonates / Q000134:cerebrospinal fluid; D001921:Brain / Q000098:blood supply; D002560:Cerebrovascular Circulation; D006801:Humans; D006985:Hyperventilation / Q000209:etiology; D007773:Lactates / Q000134:cerebrospinal fluid; D008881:Migraine Disorders / Q000134:cerebrospinal fluid* / Q000150:complications / Q000503:physiopathology; D012146:Rest; D013667:Technetium
chemical_list: D001639:Bicarbonates; D007773:Lactates; D013667:Technetium
vernacular_title: Circolazione cerebrale (misurazioni isotopiche) ed equilibrio acidobasico del liquido cefalo-rachidiano durante l'emicrania