[The role of biopharmaceutical parameters in drug development (author's transl)].
The biopharmaceutical factors, which influence the interaction between dosage form and drug activity, extend from the mode of application, through chemical and physical properties of the active constituent, to the final product, including the excipients and manufacturing processes involved. In recent years, important strides have been made in this field, which improve drug safety. This has consequently influenced and enlarged the present scope of pharmaceutical technology drug research.
D001682:Biological Availability; D001702:Biopharmaceutics; D002626:Chemistry, Pharmaceutical; D004304:Dosage Forms; D004305:Dose-Response Relationship, Drug; D004355:Drug Stability; D005860:Germany, West; D006801:Humans; D007700:Kinetics; D010316:Particle Size; D010592:Pharmaceutic Aids; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis* / Q000592:standards; D010602:Pharmacopoeias as Topic / Q000592:standards; D012995:Solubility; D013499:Surface Properties; D013557:Switzerland; D013810:Therapeutic Equivalency; D014481:United States
D004304:Dosage Forms; D010592:Pharmaceutic Aids; D004364:Pharmaceutical Preparations
Die Bedeutung biopharmazeutischer Parameter für Arzneimittelentwicklung