Embryonal rhabdomyosarcoma of head and neck in children. Correlation of stage, radiation dose, local control, and survival.
Nineteen consecutive children are analyzed according to clinical stay, radiation dose (NSD), local control, and survival. The majority received 1600 to 1750 rets and courses of actinomycin during their radiation treatments. The favorable sites were the orbit, facial soft tissue, and the larynx. The primary site control rate was 89%, and the metastatic neck control rate was 80%. The 2-year survival was 70%, and the 5-year survival was 67%. Five children are alive and well 12 to 15 years after irradiation. Late sequelae are hypoplasia of the orbit and maxillary sinus.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003609:Dactinomycin / Q000627:therapeutic use; D004428:Ear Neoplasms / Q000532:radiotherapy; D004432:Ear, Middle; D005260:Female; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D007223:Infant; D007822:Laryngeal Neoplasms / Q000532:radiotherapy; D008297:Male; D008637:Mesenchymoma / Q000188:drug therapy / Q000532:radiotherapy*; D009362:Neoplasm Metastasis; D009918:Orbital Neoplasms / Q000532:radiotherapy; D012983:Soft Tissue Neoplasms / Q000532:radiotherapy
D003609:Dactinomycin