Neural control of cochlear blood flow.
Effects of intraarterial and intravenous injections of autonomic nervous system agents on cochlear blood flow were studied in order to investigate the neural control of the inner ear vessels. Blood flow changes in the inner ear of the guinea pig were measured with an electrical impedance plethysmograph. Rather weak control of the vertebrobasilar and labyrinthine arteries by the sympathetic nervous system of the alpha-receptor type did appear to exist. Beta-receptors of the sympathetic nerve appeared to be non-existent in the cochlear vessels, and parasympathetic modulation was not evident.
D000109:Acetylcholine / Q000008:administration & dosage / Q000494:pharmacology; D000818:Animals; D003051:Cochlea / Q000098:blood supply*; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D007269:Injections, Intra-Arterial; D007275:Injections, Intravenous; D007365:Intercellular Junctions / Q000648:ultrastructure*; D007545:Isoproterenol / Q000008:administration & dosage / Q000494:pharmacology; D009638:Norepinephrine / Q000008:administration & dosage / Q000494:pharmacology; D010643:Phenoxybenzamine / Q000008:administration & dosage / Q000494:pharmacology; D012039:Regional Blood Flow / Q000187:drug effects; D011984:Sensory Receptor Cells / Q000502:physiology*; D014666:Vasomotor System / Q000502:physiology*
D010643:Phenoxybenzamine; D007545:Isoproterenol; D000109:Acetylcholine; D009638:Norepinephrine