title: [Cytogenetic and clinical investigations in trisomia 22 (author's transl)].
abstract: Since the introduction of new cytogenetic methods, as the "Pancreatin-Giemsa"-stain and similar methods, it is possible for the first time to determine the chromosomes of group G accurately. There are few cases reported in the literature with an additional small chromosome which could be associated with group G. None of those children presented the classical signs of a Down-Syndrome, therefore a trisomy 22 was discussed. This is the report of a female patient, on whom trisomy 22 was confirmed cytogenetically. So far it was only in a small number of cases possible to prove this thesis by cytogenetic studies. We compare our findings with previous reports of suspected or proven cases of trisomy 22.
mesh_terms: D002675:Child, Preschool; D002904:Chromosomes, Human, 21-22 and Y; D005260:Female; D006801:Humans; D014314:Trisomy
vernacular_title: Zytogenetische und klinische Untersuchungen einer Patientin mit einer Trisomie 22