title: Brain abscess caused by Cladosporium trichoides.
abstract: In 17 previously reported cases of cladosporiosis, no reliable therapy was described, and death occurred usually within one year of diagnosis. Pretreatment isolates from our two patients were inhibited by 6.2 mug/ml and 3.1mug/ml of flucytosine, respectively. Although both patients died, postmortem examination results showed that in one patient, the fungus had been eradicated. In the other patient, C trichoides that was isolated at postmortem examination was resistant to flucytosine treatment.
mesh_terms: D000293:Adolescent; D000328:Adult; D001344:Autopsy; D001922:Brain Abscess / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D002963:Cladosporium / Q000187:drug effects / Q000302:isolation & purification*; D005260:Female; D005437:Flucytosine / Q000494:pharmacology; D006801:Humans; D008297:Male; D008875:Middle Aged; D003904:Mitosporic Fungi / Q000302:isolation & purification*; D009181:Mycoses / Q000150:complications* / Q000473:pathology
chemical_list: D005437:Flucytosine