Quantitation of the immune rejection of allotransplanted AKR leukemic cells.
AKR leukemic cells were transferred into both CD2F1 and C3H/He mice and the growth and rejection of the cells followed by a quantitative cellular assay. While the leukemic cells initially grew at the same rate in both strains of mice, the CD2F1 mice eventually rejected the cells. The time to rejection was found to be dependent upon the initial inoculum size.
D000818:Animals; D002471:Cell Transformation, Neoplastic; D005260:Female; D007942:Leukemia, Experimental / Q000276:immunology*; D008297:Male; D051379:Mice; D008806:Mice, Inbred AKR; D008809:Mice, Inbred C3H; D009368:Neoplasm Transplantation; D013997:Time Factors; D014181:Transplantation Immunology; D014184:Transplantation, Homologous