The value of relative organ weights.
It is accepted practice in presenting organ weight data to express the results relative to the animal's body weight. The data presented suggest that in rats no benefits are obtained from this method either in reducing the variability of the data or in removing bias due to different body weights. By using simulated data it is further shown that relative weights can lead to erroneous conclusions and misinterpretation of drug effects and it is concluded that workers should present their results in absolute as opposed to relative weights.
D000311:Adrenal Glands / Q000187:drug effects; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D006321:Heart / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008297:Male; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D012107:Research Design; D013223:Statistics as Topic; D013737:Testis / Q000187:drug effects