Effects of tritiated thymidine on cell population kinetics.
This paper reports growth-kinetic data of Chinese Hamster tissue culture cells exposed at various times to differnt activities (0.05 muCi/ml up to 10.0 muCi/ml of tritiated thymidine. The analysis of the results aims at the determination of colony-size distribution and to the cellular capacity of reproduction after treatment which is reflected in the cell division spectrum within dialy intervals. The results of the growth-curves represented were converted into integrated curves of colony-size distribution, and their alteration as exponential curves for estimation of the cell cycle as a function of culture time was established. The recovery process and course determination of population kinetics following the 3H-TdR-treatments were evaluated.
D000818:Animals; D002455:Cell Division / Q000187:drug effects* / Q000528:radiation effects; D002460:Cell Line; D006224:Cricetinae; D046508:Culture Techniques; D005260:Female; D007700:Kinetics; D010053:Ovary; D011830:Radiation Effects; D013936:Thymidine / Q000031:analogs & derivatives / Q000494:pharmacology*; D014316:Tritium
D014316:Tritium; D013936:Thymidine