Elevated kidney glucosyltransferase activity in genetic prediabetic mice.
Glucosyltransferase activity in the renal cortex of genetic diabetic KK mice was significantly increased at 40 days of age when compared to that of Swiss albino and F1 hybrid mice. This increase in enzyme activity in the absence of glucose intolerance can be regarded as an earlier genetic marker for the diagnosis of diabetic microangiopathy.
D000367:Age Factors; D000818:Animals; D003920:Diabetes Mellitus / Q000201:enzymology* / Q000235:genetics; D005951:Glucose Tolerance Test; D005964:Glucosyltransferases / Q000378:metabolism*; D006168:Guinea Pigs; D007668:Kidney / Q000201:enzymology*; D011236:Prediabetic State / Q000201:enzymology*
D005964:Glucosyltransferases