title: Cold adaptation and the anaesthetic requirement for cyclopropane in rats.
abstract: The effect of cold adaptation at 4 degrees C on cyclopropane MAC was studied in 10 Wistar rats over a 16-week period. Compared with a similar control group (normally adapted), there was a significant decrease in weight gain and a significant increase in anaesthetic requirement in the cold-adapted rats.
mesh_terms: D000222:Adaptation, Physiological; D000769:Anesthesia, Inhalation / Q000379:methods; D000818:Animals; D001831:Body Temperature; D001835:Body Weight; D003080:Cold Temperature; D003521:Cyclopropanes; D004305:Dose-Response Relationship, Drug; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D003521:Cyclopropanes