title: Effect of secretin, glucagon and VIP on gallbladder contraction.
abstract: The effects on gallbladder contraction of three structurally related peptides, secretin, glucagon and the vasoactive intestinal peptide (VIP) have been compared in urethane-anesthetized guinea pigs. Secretin and glucagon had no effect alone but augmented cholecystokinin (CCK)-induced contractions. VIP decreased CCK-induced contractions.
mesh_terms: D000818:Animals; D002766:Cholecystokinin / Q000494:pharmacology; D005704:Gallbladder / Q000187:drug effects*; D005934:Glucagon / Q000494:pharmacology*; D006168:Guinea Pigs; D009119:Muscle Contraction / Q000187:drug effects*; D010455:Peptides / Q000494:pharmacology*; D012633:Secretin / Q000494:pharmacology*; D014662:Vasoconstrictor Agents / Q000494:pharmacology*
chemical_list: D010455:Peptides; D014662:Vasoconstrictor Agents; D012633:Secretin; D005934:Glucagon; D002766:Cholecystokinin