title: Genetic control of LDH isozymes in the house fly, Musca domestica.
abstract: Electrophoretic variations in lactate dehydrogenase from adult whole body homogenates are described for three laboratory strains of house flies, Musca domestica. Several crosses between different electrophoretic forms provided evidence that the observed variations are due to segregation of alleles at two distinct loci (designated as A and B loci) and that the LDH isozymes of house flies are dimers formed by a random association of subunits controlled by the two loci.
mesh_terms: D000818:Animals; D003433:Crosses, Genetic; D004591:Electrophoresis, Polyacrylamide Gel; D014644:Genetic Variation; D006793:Houseflies / Q000201:enzymology*; D006824:Hybridization, Genetic; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000032:analysis*; D009154:Mutation; D010641:Phenotype; D013045:Species Specificity
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase