[Mouse hematopoietic organs in hypokinesia].
The capacity of hemopoietic cells for colony-formation and the pattern of their differentiation during hypokinesia were studied. The absolute count of colony-forming units (CFU) decreased exponentially during 3 to 30 days. Bone marrow showed a change in the total cell count and a wave-like change in the absolute and relative count of CFU with a maximum on the 1st-3rd and 15th-45th days. Differentiating potentialities of CFU from the spleen and bone marrow were not altered towards erythro-, myelo- and thrombopoiesis. The cell structure of the peripheral blood changed, displaying lymphopenia, transient neutrophil leukocytosis, increase in the percentage content of large lymphocytes and stress-lymphocytes.
D000818:Animals; D001835:Body Weight; D002455:Cell Division; D002999:Clone Cells; D005260:Female; D006410:Hematopoiesis; D006412:Hematopoietic Stem Cells; D007103:Immobilization; D007958:Leukocyte Count; D008198:Lymph Nodes / Q000502:physiology; D051379:Mice; D009929:Organ Size; D013154:Spleen / Q000502:physiology; D013950:Thymus Gland / Q000502:physiology*
Organy krovetvoreniia mysheĭ pri gipokinezii