[Development of the breasts of the fetus. Effects of the administration of hormonal preparations during pregnancy].
The mammary glands of ten still-birth premature fetuses were studied histologically. In seven cases a combination of oestrogen-progesterone preparations were administered to the mother in early pregnancy for a duration of at least 3 months. In three cases no hormones were administered. According to our observations and the experimental work of other investigators, we may conclude that oestrogenic hormones inhibit the development of the mammary gland.
D000014:Abnormalities, Drug-Induced; D000033:Abortion, Threatened / Q000517:prevention & control; D000328:Adult; D001940:Breast / Q000196:embryology*; D004958:Estradiol / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D006908:Hydroxyprogesterones / Q000009:adverse effects* / Q000627:therapeutic use; D011247:Pregnancy
D006908:Hydroxyprogesterones; D004958:Estradiol
Développement des glandes mammaires du foetus. Effet de l'administration des préparations hormonales administrées pendant la grossesse