Presence of melatonin in plasma and urine or pinealectomized rats.
Melatonin was shown to occur in rat plasma and urine after pinealectomy by bioassay, radioimmunoassay, and thin-layer chromatography. Total daily excretion of melatonin in pinealectomized rats was about 20% of control. Light-dark rhythms of plasma melatonin levels and urinary excretion rates disappeared after pinealectomy.
D000818:Animals; D008297:Male; D008550:Melatonin / Q000097:blood / Q000378:metabolism* / Q000652:urine; D010507:Periodicity; D010870:Pineal Gland / Q000502:physiology*; D051381:Rats
D008550:Melatonin