Synthesis of some phthalazine derivatives chemically related to hydralazine.
The potent antihypertensive properties of hydralazine and dihydralazine prompted the synthesis of sixteen new phthalazine derivatives with thiosemicarbazide or beta-propionamide residues to investigate their possible antihypertensive activity.
D006830:Hydralazine / Q000031:analogs & derivatives*; D008722:Methods; D010793:Phthalazines / Q000138:chemical synthesis*; D011724:Pyridazines / Q000138:chemical synthesis*
D010793:Phthalazines; D011724:Pyridazines; D006830:Hydralazine