title: Synthesis and pharmacological activity of some 3-amino-11H-indolo[3,2-c] [1,8]naphthyridines.
abstract: The preparation of some 3-amino-11H-indolo [3,2-c]-[1,8] naphthyridines using the Fischer indole synthesis on the appropriate phenylhydrazones is described. Some compounds (IV b, c, d) were effective in inhibiting  the reactions of delayed hypersensitivity, but the testing has been discontinued because of toxicity observed.
mesh_terms: D000818:Animals; D006835:Hydrazones; D007111:Immunity, Cellular / Q000187:drug effects; D007211:Indoles / Q000138:chemical synthesis / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D009287:Naphthyridines / Q000138:chemical synthesis* / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet
chemical_list: D006835:Hydrazones; D007211:Indoles; D009287:Naphthyridines