[Effect of training for increased physical loads on the concentration and biosynthesis of ubiquinones in rat skeletal muscle].
Rats were subjected to a strenuous program of treadmill running for 2.5--3 months. Ubiquinone content was determined in the skeletal muscles and the muscle mitochondria; at the same time incorporation of labeled acetate-1-14C precursor into ubiquinone and sterols by thin muscle slices was studied. Ubiquinone and mitochondrial protein content increased in the muscles of trained rats. Incorporation of 14C into ubiquinone of trained rats increased; as to sterols, their incorporation remained unchanged.
D000085:Acetates / Q000378:metabolism; D000818:Animals; D008297:Male; D008931:Mitochondria, Muscle / Q000378:metabolism; D009132:Muscles / Q000201:enzymology*; D005082:Physical Exertion; D051381:Rats; D013261:Sterols / Q000096:biosynthesis; D014451:Ubiquinone / Q000096:biosynthesis / Q000378:metabolism*
D000085:Acetates; D013261:Sterols; D014451:Ubiquinone
Vliianie trenirovki k povyshennoĭ fizicheskoĭ nagruzke na soderzhanie i biosintez ubikhinona v skeletnykh myshtsakh krys