title: [Experimental concentration and purification of cultural antirabies vaccine].
abstract: A study of 6 series of concentrated and purified -- by ultracentrifugation -- dry cultural rabies vaccine inactivated with ultra-voilet rays demonstrated that in case of a 31--316 increase of concentration immunogenicity of the preparation rose 3--13-fold. Purification of the vaccine took place with its concentration. Additional purification of the concentrated vaccine on aluminium oxide led to a partial loss of the viral protein and to reduction of immunogenicity.
mesh_terms: D011819:Rabies Vaccines; D011820:Rabies virus / Q000032:analysis / Q000276:immunology
chemical_list: D011819:Rabies Vaccines
vernacular_title: Kontsentratsiia i ochistka kul'tural'noĭ antirabicheskoĭ vaktsiny v éksperimente