[Use of the Soviet preparation methindione for injections in convulsive conditions].
The author studied the action of a Soviet preparation Metindion in 22 patients with serial epileptic seizures and in 16 patients with an epileptic status. The studies demonstrated a high anticonvulsive activity in serial fits. In epileptical states the action of metindion was less expressed. Its combination with diazepam preparations and barbiturates appeared to have a more expressed and prolonged anticonvulsive action. Metindion is most effective when used at initial stages of a convulsive condition.
D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage / Q000627:therapeutic use*; D003975:Diazepam / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D006591:Hexobarbital / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007189:Indans / Q000008:administration & dosage / Q000627:therapeutic use*; D007192:Indenes / Q000627:therapeutic use*; D007275:Injections, Intravenous; D008297:Male
D000927:Anticonvulsants; D007189:Indans; D007192:Indenes; C001723:methindione; D006591:Hexobarbital; D003975:Diazepam
Primenenie pri sudorozhnykh sostoianiiakh otechestvennogo preparata metindiona dlia in"ektsiĭ