Marfan syndrome with coronary artery lesions in a North American Indian.
Marfan syndrome has not been well documented in North American Indians. A 19-year old Ojibwa man had evidence of this syndrome -- specifically, tall stature, long, thin extremities (particularly, fingers and toes), increased urinary excretion of hydroxyproline, aortic aneurysm, aortic regurgitation and pathologic evidence of aortic rupture and alastic tissue fragmentation. Intimal hyperplasia was present in the extramural coronary arteries, while the intramural arteries, usually thought to be involved, were normal.
D000328:Adult; D003331:Coronary Vessels / Q000473:pathology*; D006801:Humans; D007198:Indians, North American; D008297:Male; D008382:Marfan Syndrome / Q000473:pathology*; D009864:Ontario