Nuclear inclusions in Paget's disease of bone.
The ultrastructure of bone cells was examined in biopsies from 18 patients with Paget's disease of bone and from 60 patients with a variety of other bone diseases. A characteristic nuclear inclusion was found in the osteoclasts of each patient with Paget's disease. The nuclear inclusion most closely resembles viral nucleocapsids of the measles type.
D001706:Biopsy; D001842:Bone and Bones / Q000648:ultrastructure*; D002467:Cell Nucleus / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D010001:Osteitis Deformans / Q000382:microbiology / Q000473:pathology*; D010010:Osteoclasts / Q000382:microbiology / Q000473:pathology / Q000648:ultrastructure*