Juvenile hormone analogue counteracts growth stimulation and inhibition by ecdysones in clonal Drosophila cell line.
Depending on concentration, ecdysones either stimulate or inhibit proliferation of a clonal Drosophila cell line. Both effects are counteracted by ethyl dichlorofarnesoate, a juvenile hormone analogue, which by itself is growth inhibitory. Qualitatively no difference was seen between alpha- and beta-ecdysone.
D002455:Cell Division / Q000187:drug effects*; D002460:Cell Line; D004305:Dose-Response Relationship, Drug; D004330:Drosophila / Q000187:drug effects*; D004347:Drug Interactions; D004440:Ecdysone / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D007605:Juvenile Hormones / Q000494:pharmacology*
D007605:Juvenile Hormones; D004440:Ecdysone