Evidence of morphological and physiological transformation of mammalian cells by strong magnetic fields.
Cultures of L-929 and WI-38 cells, frozen to 4.2 degrees K and exposed for 4 to 8 hours to 5000-oersted magnetic fields, were markedly inhibited in their growth as compared to controls. In cultures grown on cover slips, approximately 7 days after exposure, morphologically distinct cells emerged and were propagated from generation to generation; 3 weeks later, in flask cultures, contact inhibition was abolished. It is concluded that under certain experimental conditions, strong magnetic fields induce morphological and physiological transformations of target cells.
D002455:Cell Division; D002460:Cell Line; D003260:Contact Inhibition; D004560:Electricity; D007739:L Cells; D008280:Magnetics; D013696:Temperature