Amylase: creatinine clearance ratio and urinary excretion of lysozyme in acute pancreatitis and acute duodenal perforation.
The amylase:creatinine clearance ratio in patients suffering from acute pancreatitis or acute duodenal perforation was higher than normal in both groups of patients. These findings cast doubt on the value of this parameter as a specific index of acute pancreatitis. The mechanism or mechanisms underlying the increased amylase excretion have not been determined. However, the markedly elevated urinary excretion of lysozyme observed in some patients suggests, by analogy, that diminished tubular reabsorption of amylase may contribute towards the elevated amylase:creatinine ratio.
D000208:Acute Disease; D000681:Amylases / Q000378:metabolism*; D003404:Creatinine / Q000378:metabolism*; D004381:Duodenal Ulcer / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate; D009113:Muramidase / Q000652:urine*; D010195:Pancreatitis / Q000201:enzymology / Q000378:metabolism*; D010439:Peptic Ulcer Perforation / Q000201:enzymology / Q000378:metabolism*
D003404:Creatinine; D000681:Amylases; D009113:Muramidase