title: Unusually high pacemaker threshold in severe myxedema. Decrease with thyroid hormone therapy.
abstract: In a patient with myxedema and complete heart block, an usually high pacemaker threshold was observed initially during transvenous right ventricular endocardial pacing. The pacemaker threshold gradually decreased with thyroid replacement therapy, suggesting that the lack of thyroid hormone in some patients might increase the pacemaker threshold.
mesh_terms: D000219:Adams-Stokes Syndrome / Q000150:complications; D000368:Aged; D006327:Heart Block / Q000150:complications / Q000628:therapy; D006801:Humans; D008297:Male; D009230:Myxedema / Q000150:complications* / Q000188:drug therapy; D010138:Pacemaker, Artificial; D013974:Thyroxine / Q000627:therapeutic use*
chemical_list: D013974:Thyroxine