A staging system for forelimb regeneration in the axolotl, Ambystoma mexicanum.
A staging system has been devised for normal regeneration from the upper arm in the mature axolotl. It consists of seven externally definable stages: (1) Wound healing (WH): (2) Dedifferentiation (DD); (3) Early bud (EB); (4) Medium bud (MB); (5) Late bud (LB); (6) Palette (Pal), and (7) Digital outgrowth (DO). Serial histological sections of 38 regenerating limbs were used to correlate gross stages with microscopic events in the regenerative process.
D000557:Ambystoma / Q000502:physiology*; D000818:Animals; D001861:Bone Regeneration; D005552:Forelimb / Q000502:physiology*; D012038:Regeneration; D012867:Skin / Q000033:anatomy & histology; D012879:Skin Physiological Phenomena; D009626:Terminology as Topic; D013997:Time Factors; D014945:Wound Healing