An improved method for the production of experimental congestive heart failure in the guinea-pig.
The method involves supravalvular aortic constriction, and a simple, efficient, aortic constrictor has been developed which gives highly predictable results. Mortality due to causes directly related to the surgical procedure was low.
D000818:Animals; D001011:Aorta; D003250:Constriction; D006168:Guinea Pigs; D006333:Heart Failure / Q000209:etiology / Q000662:veterinary*; D008297:Male; D008722:Methods; D012376:Rodent Diseases / Q000209:etiology*