[Effect of diet on deiodination of L-diiodotyrosine and L-thyroxine in rat liver].
Male Wistar rats of same weight were used to study the effects of diets containing, respectively, 3 and 50 per cent (by weight) fat on the deiodination of L-di-iodotyrosine and L-thyroxin in the liver. For this purpose, liver homogenate supernatants were analysed. The deiodination of L-di-iodotyrosine was significantly lower in the animals on high-fat diet than in those on low-fat diet, whereas the deiodination of L-thyroxin was significantly higher. It is concluded that not the body weight, but the diet influences the extent of deiodination.
D000367:Age Factors; D000818:Animals; D004041:Dietary Fats; D004105:Diiodotyrosine / Q000378:metabolism*; D007455:Iodine / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008297:Male; D051381:Rats; D013974:Thyroxine / Q000378:metabolism*
D004041:Dietary Fats; D004105:Diiodotyrosine; D007455:Iodine; D013974:Thyroxine
Diätetische Beeinflussung der Dejodierung von L-Dijodtyrosin und L-Thyroxin in der Leber bei Ratten