title: [Acute leukemia as terminal stage of Hodgkin's disease (author's transl)].
abstract: In a 61 year-old female patient with Hodgkin's disease treated with cytotoxic drugs and radiation therapy acute undifferentiated leukemia developed 10 years later. The possibility of a carcinogenic effect of the cytotoxic and actinic therapy is discussed. Leukemia complicating the course of Hodgkin's disease must be considered an independent disease and not a iatrogenic transformation of a preexisting lesion.
mesh_terms: D000208:Acute Disease; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001853:Bone Marrow / Q000473:pathology; D001854:Bone Marrow Cells; D005260:Female; D006689:Hodgkin Disease / Q000150:complications*; D006801:Humans; D007938:Leukemia / Q000139:chemically induced / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D010996:Pleural Effusion / Q000150:complications; D011878:Radiotherapy / Q000009:adverse effects*
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Akute Leukämie als Terminalstadium einer Lymphogranulomatose