[Antitumor activity of the lymphocytes of BALB/c and C57BL mice during methylcholanthrene carcinogenesis].
By means of the elaborated by the authors method of inhibition by lymphocytes of spheroids production by tumor cells a quantitative estimation of their antitumor activity is given in mice BALB/c and C57BL in methylcholanthrene carcinogenesis, Lymphoid cells in mice BALB/c proved to be more active functionally than lymphocytes in mice C57BL. Antitumor action of the lymphocytes is high enough at early stages of blastoma development, lymphocytes from remote lymph nodes being mostly active. At terminal stage the effector action of lymphocytes is diminished.
D000818:Animals; D046508:Culture Techniques; D003601:Cytotoxicity Tests, Immunologic; D008198:Lymph Nodes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008748:Methylcholanthrene; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D009374:Neoplasms, Experimental / Q000139:chemically induced* / Q000276:immunology
D008748:Methylcholanthrene
Protivoopukholevaia aktivnost' limfotsitov mysheĭ BALB/c i C57BL pri metilkholantrenovom kantserogeneze