[Variations in local cerebral blood volume depending on the mean arterial blood pressure in man].
A radio isotopic technique is described to measure and monitor the cerebral blood volume during a controlled arterial hypotension induced by sodium nitroprusside in anesthetised patients (neurolepanalgesia) submited to surgery for a ruptured saccular aneurysm. The study was made in 10 cases from 90 mm Hg to 30 mm Hg mean blood pressure monitored from a transducer connected to an intra humeral microcatheter. The figures obtained show an increase of the cerebral blood volume from 90 mm Hg to 50 mm Hg in every patient and a linear correlation when the pressure is lowered under 50 mm Hg level; therefore under a mean arterial pressure of 50 mm Hg the autoregulation arterial mechanism is out of work.
D001794:Blood Pressure; D001810:Blood Volume; D002560:Cerebrovascular Circulation; D006706:Homeostasis; D006801:Humans; D002532:Intracranial Aneurysm / Q000503:physiopathology
Variations du volume sanguin cérébral local en fonction de la pression artérielle moyenne chez l'homme