The effect of valium on myocardial blood flow.
The effect of Valium on coronary blood flow was studied. In 18 patients undergoing coronary angiography, total and regional myocardial blood flow was determined by the 133Xe wash-out technique. A total of 39 pre- and 39 post-Valium injection wash-out curves were constructed. Results indicate (99% confidence) that intravenous Valium injection (0.1 mg/kg body weight) decreases myocardial blood flow 12--15%.
D000792:Angiography; D003326:Coronary Circulation / Q000187:drug effects*; D003975:Diazepam / Q000494:pharmacology*; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D014980:Xenon Radioisotopes
D014980:Xenon Radioisotopes; D003975:Diazepam