[Autosomal dominant hereditary atrial septal defect with heart conduction defects and mitral valve insufficiency].
An autosomal dominant inherited ASD with conduction defects in one family is described. 6 members of 4 generations were fallen ill. In 4 patients the diagnosis was made clinically, in 2 sisters the diagnosis was confirmed by operation. Moreover, the last 2 patients had a mitral insufficiency--probably congenital. The ecg-findings of 4 patients additionally showed conduction defects in form of AV-and bundle branch blocks.
D000328:Adult; D001145:Arrhythmias, Cardiac / Q000150:complications / Q000235:genetics*; D002037:Bundle-Branch Block / Q000235:genetics; D002648:Child; D004562:Electrocardiography; D005260:Female; D005799:Genes, Dominant; D006327:Heart Block / Q000235:genetics; D006344:Heart Septal Defects, Atrial / Q000150:complications / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000235:genetics*; D010375:Pedigree
Autosomal dominant vererbter Vorhofseptumdefekt mit Reizleitungsstörungen und Mitralinsuffizienz