Significance of impulse activity in the transformation of skeletal muscle type.
The changes which follow cross reinnervation of mammalian fast and slow twitch muscles may reflect a capacity of skeletal muscle to respond adaptively to different functional requirements. This interpretation is supported by experiments in which long-term electrical stimulation was used both to reproduce and to oppose the effects of cross reinnervation.
D000200:Action Potentials; D000222:Adaptation, Physiological; D000818:Animals; D004558:Electric Stimulation; D009119:Muscle Contraction; D009132:Muscles / Q000294:innervation*; D011817:Rabbits; D013997:Time Factors