title: Effects of whole body Co-60 irradiation on the testes and epididymides of hedgehog (Hemiechinus auritus Collaris): a biochemical analysis.
abstract: The effects of 575 and 875 Rontgen (R) of whole-body irradiation in common Indian hedgehog (Hemiechinus auritus Collaris) were studied. At 875 R it showed typical signs and symptoms of radiation sickness, transient body loss and radiation mortality. Extensive vasculitis, pyknosis, chromatorrhexix and chromatolysis was noticed in the testes of irradiated hedgehogs. Epididymides and vas deferens were devoid of spermatozoa. Whole body irradiation inhibited the RNA, protein and sialic acid synthesis in the testes. Total cholesterol per gram of testes was increased significantly. Sialic acid contents of the irradiated epididymides were low. Reduced androgen production was confirmed in non-active Leydig cells, with diminished sex accessory organs and decreased fructose contents in the seminal vesicles of irradiated hedgehogs.
mesh_terms: D000818:Animals; D003037:Cobalt Radioisotopes; D004822:Epididymis / Q000032:analysis / Q000528:radiation effects*; D005632:Fructose / Q000032:analysis; D006364:Hedgehogs; D008055:Lipids / Q000032:analysis; D008297:Male; D011506:Proteins / Q000032:analysis; D012313:RNA / Q000032:analysis; D012669:Seminal Vesicles / Q000032:analysis / Q000528:radiation effects*; D012794:Sialic Acids / Q000032:analysis; D013737:Testis / Q000032:analysis / Q000528:radiation effects*
chemical_list: D003037:Cobalt Radioisotopes; D008055:Lipids; D011506:Proteins; D012794:Sialic Acids; D005632:Fructose; D012313:RNA