title: Decidualisation in the prepuberal rat uterus.
abstract: Decidualisation has been experimentally induced in the prepuberal rat. It is morphologically similar to that obtained in the adult. The cytodifferentiation includes the formation of binucleated cells and extensive specialised cellular junctions. Furthermore, blastocysts from adults transferred into uterine horns of immature specimens implant and develop, indicating that the decidual response they induce is functionally comparable to the uterine response at the time of nidation in the fertilised adult. The model of the experimental decidual induction in the immature is used to study the ontogenic processes of uterine maturation. Preliminary observations indicate that the 7-10-days period might be of significance in the maturation of the rat uterus.
mesh_terms: D000367:Age Factors; D000818:Animals; D002454:Cell Differentiation; D003656:Decidua / Q000254:growth & development* / Q000648:ultrastructure; D004054:Diethylstilbestrol / Q000494:pharmacology; D010064:Embryo Implantation / Q000187:drug effects; D004624:Embryo Transfer; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D008854:Microscopy, Electron; D011247:Pregnancy; D011374:Progesterone / Q000494:pharmacology; D051381:Rats; D012715:Sesame Oil / Q000494:pharmacology; D013997:Time Factors; D014599:Uterus / Q000254:growth & development
chemical_list: D011374:Progesterone; D004958:Estradiol; D004054:Diethylstilbestrol; D012715:Sesame Oil