Interactions of adenine, thymine, and uracil with epinephrine: UV studies.
Based upon UV absorption studies, charge transfer complex formations by the nucleic acid bases adenine, thymine, and uracil with epinephrine were demonstrated. The pertient equilibrium constants were calculated by assuming 1:1 complexes using the Benesi-Hildebrand equation and were found to decrease in the following order: uracil-epinephrine greater than thymine-epinephrine greater than adenine-epinephrine. The values of delta G degrees, delta H degrees, and delta S degrees were calculated for the various interactions. Theoretical arguments are presented as to the possible stoichiometries of the various complexes existing in aqueous solutions. The electron-donating or electron-accepting abilities of the interacting molecular species are discussed.
D000225:Adenine; D055598:Chemical Phenomena; D002621:Chemistry; D003596:Cytosine; D004837:Epinephrine; D013056:Spectrophotometry, Ultraviolet; D013941:Thymine; D014498:Uracil
D014498:Uracil; D003596:Cytosine; D000225:Adenine; D013941:Thymine; D004837:Epinephrine