Phaeomelanic pigments from a human melanoma.
The pigments in melanomas from 2 patients were studied with regard to solubility and chemical composition. Melanoma pigment from a patient with red-blonde hair was alkali-soluble and contained 9 or 10% sulfur and was thus of phaeomelanic type. Melanoma pigment from a patient with red-brown hair was insoluble in 0.2 N NaOH. Its sulfur content was 6%. This pigment was eumelanic with regard to solubility characteristics but the sulfur content was higher than previously observed for eumelanin.
D000328:Adult; D005260:Female; D006200:Hair Color; D006801:Humans; D007414:Intestinal Neoplasms / Q000378:metabolism; D008113:Liver Neoplasms / Q000378:metabolism*; D008297:Male; D008543:Melanins / Q000032:analysis / Q000096:biosynthesis*; D008545:Melanoma / Q000378:metabolism*; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010858:Pigmentation; D013455:Sulfur / Q000032:analysis
D008543:Melanins; D013455:Sulfur