Functional recovery from spinal cord trauma following dexamethazone and chlorpromazine therapy in dogs.
The spinal cords of 20 normal dogs were exposed via dorsal laminectomies and damaged with a known impact force. Ten dogs were treated with dexamethazone and 10 dogs with chlorpromazine for five days after surgery. The results showed that neither drug had a significantly beneficial effect on the functional recovery of the spinal cords, when compared to a control group of similarly traumatised dogs.
D000818:Animals; D002746:Chlorpromazine / Q000627:therapeutic use*; D003907:Dexamethasone / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D005260:Female; D008297:Male; D013119:Spinal Cord Injuries / Q000188:drug therapy / Q000662:veterinary*
D003907:Dexamethasone; D002746:Chlorpromazine