Thiamine diphosphatase in rat small intestine.
TDPase is located mostly in the proximal portion of the small intestine and its activity, like that of ALPase, decreased markedly in thiamine deficiency. The decreased enzyme activities were restored after thiamine or vitamin D3. Kinetic and other studies of the purified enzyme indicated the identity of the two enzymes.
D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D007413:Intestinal Mucosa / Q000201:enzymology; D007421:Intestine, Small / Q000201:enzymology*; D007700:Kinetics; D008297:Male; D011755:Pyrophosphatases / Q000378:metabolism*; D051381:Rats; D013832:Thiamine Deficiency / Q000201:enzymology*; D013834:Thiamine Pyrophosphatase / Q000378:metabolism*
D000469:Alkaline Phosphatase; D011755:Pyrophosphatases; D013834:Thiamine Pyrophosphatase