title: Decoquinate in the control of experimentally induced coccidiosis of calves.
abstract: Decoquinate administered orally in a grain mix at dosages of 0.5, 0.538, 0.7, and 0.8 mg/kg of body weight suppressed oocyst discharge and bloody diarrhea in calves inoculated 3 days later with 100,000 oocysts of Eimeria bovis (experiment 1, n = 12 calves) or with 100,000 oocysts each of E bovis and Eimeria zuernii (experiment 2, n = 16 calves). Doses of 0.1, 0.163, 0.243, 0.3, and 0.362 mg/kg of body weight gave only partial suppression of oocyst discharge and diarrhea. Clinical signs of coccidiosis did not recur for 23 days after the treatment was discontinued.
mesh_terms: D000284:Administration, Oral; D000821:Animal Feed; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D003048:Coccidiosis / Q000188:drug therapy / Q000662:veterinary*; D003667:Decoquinate / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006912:Hydroxyquinolines / Q000627:therapeutic use*
chemical_list: D006912:Hydroxyquinolines; D003667:Decoquinate