Evidence for an extranucleolar mechanism of actinomycin D action.
D000546:Amanitins / Q000494:pharmacology; D000818:Animals; D002466:Cell Nucleolus / Q000187:drug effects / Q000378:metabolism; D002467:Cell Nucleus / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D002474:Cell-Free System; D012321:DNA-Directed RNA Polymerases / Q000037:antagonists & inhibitors; D003609:Dactinomycin / Q000494:pharmacology*; D008099:Liver / Q000648:ultrastructure; D012333:RNA, Messenger / Q000096:biosynthesis*; D012335:RNA, Ribosomal / Q000096:biosynthesis*; D051381:Rats; D014158:Transcription, Genetic / Q000187:drug effects*
D000546:Amanitins; D012333:RNA, Messenger; D012335:RNA, Ribosomal; D003609:Dactinomycin; D012321:DNA-Directed RNA Polymerases