Rapid detection of glyoxalase I (GLO) on cellulose acetate gel and the distribution of GLO variants in a Dutch population.
A rapid electrophoretic procedure is described for detecting the human red cell glyoxalase I variants (GLO 1, GLO 2-1, and GLO 2) on cellulose acetate gel (cellogel) on which the sites of enzymed activity are visualized as purple bands against white background. The frequency of GLO1 gene in a Dutch population living in and around Leiden was found to be 0.4544.
D004588:Electrophoresis, Cellulose Acetate / Q000379:methods; D005787:Gene Frequency; D014644:Genetic Variation; D006801:Humans; D007791:Lactoylglutathione Lyase / Q000097:blood*; D008190:Lyases / Q000097:blood*; D009426:Netherlands; D010641:Phenotype
D008190:Lyases; D007791:Lactoylglutathione Lyase