[Intraocular cryptococcosis (author's transl)].
A 79-year-old female patient suffered from iridocyclitis of both eyes. In the fundus of the left eye equatorially a preretinal questionable granuloma (size 1/2 d.d.) was found; the first hint of a mycotic involvement. In the enucleated right bulbus, an abscess-like granulomatous focus with a diameter of 10 mm was found. Several round encapsulated cells having a diameter of 7 to 20 mu and looking like with Cryptococcus neoformans were microscopically demonstrable in the pus obtained from this abscess. Since the fungus could not be cultured, it may be assumed that a spontaneous healing occurred. The only known basic disease was a temporary uremia (330 mg0/0 urea and 7.0 mg0/0 creatinin). The role of amphotericin B therapy in this patient is discussed.
D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D003453:Cryptococcosis / Q000188:drug therapy / Q000382:microbiology*; D003454:Cryptococcus / Q000302:isolation & purification; D005128:Eye Diseases / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans
D000666:Amphotericin B
Intraokulare Cryptococcose