Denudation of the urinary bladder mucosa in the cat by formaldehyde.
Chemical Stripping of the urinary bladder mucosa was studied in 38 cats using 5 to 25% formaldehyde solutions. The contact time varied from 1 to 20 min. With a 20% solution and contact time of 1 min, total denudation was possible without necrosis of subepithelial layers. In such cases, complete reepithelialisation and normal bladder dynamics were seen within 3-4 weeks after formaldehyde instillation. Signs of formaldehyde intoxication due to vesical resorption were not observed.
D000818:Animals; D002415:Cats; D004305:Dose-Response Relationship, Drug; D004848:Epithelium / Q000187:drug effects / Q000473:pathology; D005260:Female; D005557:Formaldehyde / Q000008:administration & dosage / Q000494:pharmacology*; D009092:Mucous Membrane / Q000187:drug effects / Q000473:pathology; D009336:Necrosis; D001743:Urinary Bladder / Q000187:drug effects* / Q000473:pathology
D005557:Formaldehyde