Effects of dianabol and high-intensity sprint training on body composition of rats.
The effects on body composition and organ weights of anabolic steroid administration and of high-intensity sprint running, separately and in combination, were studied in young adult male rats. Dianabol (methandrostenolone) 1 mg/day for 8 weeks had no significant effects on muscle weight or lean body mass in either the trained or the sedentary animals. The program of sprint training resulted in a lower body weight, a lesser percentage of body fat (Runners, 8.5%, vs. sedentary, 13.5% P less than 0.01) and a greater relative lean body mass (runners, 91.5% vs. sedentry, 86.5%, P less than 0.01). We conclude from these results that (a) normal androgen levels in young, healthy male animals are sufficiently high so that the addition of a large dose of anabolic steroid does not result in stimulation of additional muscle growth, and (b) the changes in body composition induced by high-intensity, short-duration sprint training are qualitatively similar to those seen with endurance exercise training.
D000311:Adrenal Glands / Q000032:analysis; D000818:Animals; D001823:Body Composition / Q000187:drug effects; D006321:Heart / Q000033:anatomy & histology; D007668:Kidney / Q000033:anatomy & histology; D008099:Liver / Q000033:anatomy & histology; D008297:Male; D008696:Methandrostenolone / Q000494:pharmacology*; D009132:Muscles / Q000033:anatomy & histology; D009929:Organ Size; D010919:Placebos; D051381:Rats; D012420:Running; D013737:Testis / Q000033:anatomy & histology
D010919:Placebos; D008696:Methandrostenolone