Spontaneous contractility and the response of the human uterine cervix to prostaglandins F2alpha and E2 during the menstrual cycle.
The effect of prostaglandins E2 and F2alpha on the contractility of the uterine cervix was investigated in nonpregnant women throughout the menstrual cycle. PGF2alpha was found stimulatory to the cervix at all phases of the menstrual cycle, whereas PGE2 was inhibitory. The relaxing effect of PGE2 was most marked during midcycle.
D002584:Cervix Uteri / Q000187:drug effects*; D005260:Female; D006801:Humans; D008598:Menstruation; D011458:Prostaglandins E / Q000494:pharmacology*; D011460:Prostaglandins F / Q000494:pharmacology*; D014590:Uterine Contraction / Q000187:drug effects*; D014599:Uterus / Q000187:drug effects
D011458:Prostaglandins E; D011460:Prostaglandins F