[Displacement currents of the sodium channels of the membranes of Ranvier's nodes].
A method to record the displacement current in nodal membrane is described and results obtained on nerve fibres from the frog Rana ridibunda are presented. This current is shown to be due to displacement of charges from an initial state, associated with a large negative membrane potential, to a final state. The dependence of the charge displacement on the membrane potential and degree of inactivation of the sodium channels suggests that the displacement current observed in these experiments is associated with activation of m-gates of the sodium channels. The density of the sodium channels in nodal membrane of Rana ridibunda determined from the density of the charge displaced is about 5000 channels/mum2.
D000818:Animals; D004594:Electrophysiology; D008564:Membrane Potentials; D011898:Ranidae / Q000502:physiology; D011901:Ranvier's Nodes / Q000502:physiology*; D012964:Sodium / Q000502:physiology*
D012964:Sodium
Toki smeshcheniia natrievykh kanalov membrany perekhvata Ranv'e