title: The separation, identification, and quantitation of cannabinoids and their tau=butyldimethylsilyl, trimethylsilylacetate, and diethylphosphate derivatives using high-pressure liquid chromatography, gas-liquid chromatography, and mass spectrometry.
abstract: Methods for the separation, identification, and quantitation, of cannabinoids present in hashish have been developed. These methods include high-pressure liquid chromatographic and gas-liquid chromatographic separation of cannabinol, delta 9-tetrahydrocannabinol, delta 8-tetrahydrocannabinol, and cannabidiol as well as their tau-butyidimethylsilyl either and trimethylsilylacetate derivatives. The necessity for internal standards; the sensitivity of the HPLC method; and some mass spectral fragmentation pathways for the tau-butyldimethylsily, trimethylsilylacetate, and diethylphosphate derivatives are discussed.
mesh_terms: D002186:Cannabinoids / Q000032:analysis*; D002188:Cannabis / Q000032:analysis; D002849:Chromatography, Gas / Q000379:methods; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D013759:Dronabinol / Q000031:analogs & derivatives; D013058:Mass Spectrometry / Q000379:methods
chemical_list: D002186:Cannabinoids; D013759:Dronabinol