Depressed phagocytic function exhibited by polymorphonuclear leucocytes from chronically iron deficient rabbits.
The production of chronic iron deficiency in rabbits was associated with impaired phagocytosis of opsonized Staphylococcus aureus by their polymorphonuclear leucocytes. These cells had a reduced ability to ingest the bacteria and the rate of ingestion could not be stimulated by autologous serum leucophilic gamma-globulin.
D000747:Anemia, Hypochromic / Q000097:blood*; D000818:Animals; D002908:Chronic Disease; D005260:Female; D007074:Immunoglobulin G / Q000378:metabolism; D009504:Neutrophils; D009895:Opsonin Proteins; D010587:Phagocytosis; D011817:Rabbits; D013211:Staphylococcus aureus / Q000276:immunology
D007074:Immunoglobulin G; D009895:Opsonin Proteins