title: [Morphological effects in rats following a 22-day space flight].
abstract: A morphological examination of 27 rats flown onboard the biosatellite and sacrificed on the 1st-2nd and 26-27th postflight days demonstrated no significant changes in the structural organization of the vital organs and systems of the animal body. It was, however, found that the space exposure induced morphologically detectable changes in the musculo-skeletal system, hemo- and lymphopoiesis, hypothalamic-pituitary-adrenal system and the juxtaglomerular apparatus of the kidneys. The changes were reversible and nonspecific, and could be seen in animals exposed to ground-based hypokinetic and other stress experiments. Postflight the animals developed some reactions that were similar to those in humans. This helps to identify the morphological substrate of certain changes in the human body and to investigate their pathogenesis.
mesh_terms: D000818:Animals; D001842:Bone and Bones; D002319:Cardiovascular System; D004064:Digestive System; D004702:Endocrine Glands; D006413:Hematopoietic System; D008168:Lung; D008208:Lymphatic System; D009132:Muscles; D009490:Neurosecretory Systems; D009929:Organ Size; D051381:Rats; D013026:Space Flight; D013997:Time Factors; D014551:Urinary Tract
vernacular_title: Morfologicheskie éffekty u krys posle 22-sutochnogo kosmicheskogo poleta