90Sr + 90Y bremsstrahlung efficiency predicted for humans.
Bremsstrahlung x-rays are produced when energetic beta-particles are emitted and absorbed. Measurements of total-body bremsstrahlung efficiencey (x-ray photon output per muCi 90Sr in the body, relative to that in water) have been made in the intact mouse, rat, rabbit, and dog sacrificed 2 weeks after the injection of 90Sr + 85Sr. Efficiencies were determined by a comparison of the bremsstrahlung output from 90Sr + its daughter 90Y and the gamma-ray emission of 85Sr. Results were checked by a beta-assay of the ashed animals. Bremsstrahlung efficiencies averaged 1.10 in a 0.04 kg mouse, 1.14 in a 0.13 kg rat, 1.23 in a 2.6 kg rabbit, and 1.32 in an 8.5 kg beagle. Extrapolating to a 70 kg human, a relative bremsstrahlung efficiency of about 1.4 is predicted. An estimate was made of the 90Sr body content in a former dial painter based on in vivo counting and a bremsstrahlung efficiency of 1.39 predicted for a 55 kg human female by these animal data. Our value of 1.42 +/- 0.08 muCi 90Sr was in good agreement with corresponding results reported for this subject by 8 other laboratories.
D000818:Animals; D001822:Body Burden; D001842:Bone and Bones / Q000032:analysis; D004285:Dogs; D005260:Female; D006801:Humans; D051379:Mice; D011817:Rabbits; D051381:Rats; D013326:Strontium Radioisotopes / Q000032:analysis; D015021:Yttrium Radioisotopes / Q000032:analysis
D013326:Strontium Radioisotopes; D015021:Yttrium Radioisotopes