Hepatitis and bone destruction as uncommon manifestations of early syphilis. Report of a case.
We describe a patient with a painful lytic lesion of the clavicle and a granuloma of the liver in late secondary syphilis. The classic "moth-eaten" alopecia of the scalp as well as eyebrows and eyelashes suggested syphilis, although an initial false-negative VDRL test for syphilis (prozone phenomenon) caused a delay in diagnosis. Bone as well as liver involvement in early syphilis may be more common than previously recognized.
D000328:Adult; D000505:Alopecia / Q000209:etiology; D001862:Bone Resorption / Q000000981:diagnostic imaging / Q000209:etiology*; D002968:Clavicle / Q000000981:diagnostic imaging; D006505:Hepatitis / Q000209:etiology*; D006801:Humans; D008297:Male; D010400:Penicillin G / Q000627:therapeutic use; D011859:Radiography; D013587:Syphilis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
D010400:Penicillin G