title: On the genetics and population genetics of Gm(4).
abstract: Investigations on 70 German families with 142 children confirmed the autosomal-dominant inheritance of Gm(4). However, in our material as well as in the materials published so far, Gm(4) X Gm(-4) parental combinations show clear surplusses of Gm(4) and deficits of Gm(-4) children, which might indicate prenatal selection. The world distribution of Gm4 alleles reveals a remarkable racial heterogeneity. Furthermore, marked North-South distribution gradients in Caucasoids and Mongoloids were found. The genetical and population genetical observations are discussed.
mesh_terms: D000328:Adult; D000810:Angola; D044466:Asian People; D044383:Black People; D001789:Blood Group Antigens; D002031:Bulgaria; D002648:Child; D005828:Genetics, Population; D005860:Germany, West; D006801:Humans; D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G; D007194:India; D044468:Native Hawaiian or Pacific Islander; D010641:Phenotype; D011995:Recombination, Genetic; D044465:White People
chemical_list: D001789:Blood Group Antigens; D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G