The clinical classification of ceroid-lipofuscinosis. A statistical approach.
A revision of 108 published cases from the last ten years has been made, of patients suffering ceroid-lipofuscinosis, which includes two cases studied in our department. The statistical analysis of the initial symptoms, the age of onset and the disease's duration, permits us to conclude that possibly there exists, within this syndrome, four different forms in accordance with the age of onset. Each one of them has a typical clinical pattern. Our classification was compared with previously existing ones.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002566:Ceroid / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000503:physiopathology; D006801:Humans; D007223:Infant; D008064:Lipidoses / Q000145:classification* / Q000503:physiopathology; D008062:Lipofuscin / Q000378:metabolism; D001523:Mental Disorders / Q000503:physiopathology; D008875:Middle Aged; D009069:Movement Disorders / Q000503:physiopathology; D009420:Nervous System / Q000378:metabolism; D013577:Syndrome; D014786:Vision Disorders / Q000503:physiopathology
D002566:Ceroid; D008062:Lipofuscin