Improvement in lacrimal and salivary secretions after alkali therapy in Sjøgren's syndrome with renal tubular acidosis.
A patient with Sjøgren's syndrome developed renal tubular acidosis which led to systemic acidosis and potassium depletion. Treatment with Shohl's solution and potassium supplements was followed by subjective improvement in tear flow, salivary flow, and by disappearance of bronchitic symptoms. Detailed objective assessments were then made during the next year, twice on treatment and twice without. These confirmed the subjective impression of improvement.
D000141:Acidosis, Renal Tubular / Q000188:drug therapy* / Q000209:etiology; D002951:Citrates / Q000627:therapeutic use*; D006801:Humans; D007765:Lacrimal Apparatus / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000627:therapeutic use*; D011191:Potassium Deficiency / Q000188:drug therapy; D012469:Salivary Glands / Q000378:metabolism*; D012859:Sjogren's Syndrome / Q000150:complications* / Q000188:drug therapy
D002951:Citrates; D011188:Potassium