[Transformation of secretory cylindrial cells into ciliar cells in the epithelium of the human uterine cervix (functional transformation of highly differentiated cells)].
By electron microscopical investigations of the cylindrical epithelium of the human cervix uteri we could show that in ciliar cells a regeneration of ciliars is possible. There is a discussion about the question whether the pinching off of ciliars is the beginning of a transformation process into a secretory cell. The functional change of secretory cells to ciliar cells becomes obvious by the existence of so-called granulo-filamentary bodies in the cytoplasm of ciliar cells. These bodies grow by a granulo-filamentary transformation of secretory granules. As these granulo-filamentary bodies do not take place in the extrusion process but stay in the cytoplasm they may thus be used as an indicator which shows the finished transformation process of a secretory cell into a ciliar cell.
D002455:Cell Division; D002584:Cervix Uteri / Q000648:ultrastructure*; D002923:Cilia / Q000502:physiology*; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D010060:Ovulation
Uber die Transformation sekretorischer Zylinderzellen zu Flimmerzellen im Epithel der menschlichen Cervix uteri (Zugleich ein Beitrag zur Frage nach dem Funktionswandel hochdifferenzierter Zellen)