Cytochemical studies of peripheral blood granulocytes and lymphocytes in patients with systemic lupus erythematosus.
Using cytoenzymatic methods the activity of acid and alkaline phosphatase, non-specific esterase and glycogen content in peripheral blood cells were analyzed. A statistically significant rise in the activity of these enzymes was demonstrated in granulocytes and lymphocytes and a low level of glycogen in lymphocytes. Following prednisone treatment a statistically significant decrease was observed in the activity of studied enzymes and a rise in glycogen content.
D000135:Acid Phosphatase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D004950:Esterases / Q000097:blood; D006098:Granulocytes / Q000201:enzymology*; D006801:Humans; D007962:Leukocytes / Q000201:enzymology*; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy / Q000201:enzymology*; D008214:Lymphocytes / Q000201:enzymology*; D011241:Prednisone / Q000627:therapeutic use; D013997:Time Factors
D004950:Esterases; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D011241:Prednisone