title: The effect of sulfhydryl reagents upon the activity of 40S ribosomal subunits.
abstract: p-Chloromercuribenzoate inhibited the poly (U)-dependent binding of the Phe-tRNA to the 40S ribosomal subunit but displayed no inhibitory effect on the binding of poly (U) to the ribosome. Other sulfhydryl reagents tested, like N-ethylmaleimide and iodoacetamide, did not affect the binding of Phe-tRNA to the small ribosomal subunit.
mesh_terms: D002729:Chloromercuribenzoates / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D006801:Humans; D014066:Palatine Tonsil / Q000648:ultrastructure; D011072:Poly U / Q000378:metabolism; D012343:RNA, Transfer / Q000378:metabolism; D012270:Ribosomes / Q000187:drug effects* / Q000378:metabolism; D013439:Sulfhydryl Reagents / Q000494:pharmacology*; D013696:Temperature
chemical_list: D002729:Chloromercuribenzoates; D013439:Sulfhydryl Reagents; D011072:Poly U; D012343:RNA, Transfer