title: Urea cycle enzymes in the liver of a dolphin Platanista indi.
abstract: Urea cycle enzymes are all shown to be active in dolphin liver. Acetylglutamate-independent cytoplasmic carbamylphosphate synthase is also present. Arginase is a basic protein, although less markedly basic than the dog enzyme. It is 118 per cent activated by heating at 50 degrees. Optimum pH is 10.5. Co++ and Ni++ inhibit the enzyme. AMP deaminase, glutamicoxaloacetic transaminase, glutamate dehydrogenase and ornithine transaminase are also active in dolphin liver.
mesh_terms: D000659:AMP Deaminase / Q000378:metabolism; D000818:Animals; D001119:Arginase / Q000378:metabolism; D001123:Argininosuccinate Lyase / Q000378:metabolism; D001124:Argininosuccinate Synthase / Q000378:metabolism; D001219:Aspartate Aminotransferases / Q000378:metabolism; D002223:Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) / Q000378:metabolism; D003600:Cytosol / Q000201:enzymology; D004289:Dolphins / Q000378:metabolism*; D006801:Humans; D008099:Liver / Q000201:enzymology*; D008930:Mitochondria, Liver / Q000201:enzymology; D009954:Ornithine Carbamoyltransferase / Q000378:metabolism; D010527:Perissodactyla; D051381:Rats; D013045:Species Specificity; D014508:Urea / Q000378:metabolism*
chemical_list: D014508:Urea; D009954:Ornithine Carbamoyltransferase; D001219:Aspartate Aminotransferases; D001119:Arginase; D000659:AMP Deaminase; D001123:Argininosuccinate Lyase; D001124:Argininosuccinate Synthase; D002223:Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)