title: Trimethoxypsoralen in vitiligo.
abstract: The treatment of vitiligo has been unsatisfactory. Introduction of systemic furocoumarins to treatment regimens has given very promising results. Trimethylpsoralen has been found to be more potent than 8-methoxypsoralen. In cases studied, ultraviolet irradiation of affected sites following topical application of trimethylpsoralen was found to hasten the process of repigmentation. Simultaneous treatment of underlying disease produced a quicker response followed by sustained relief.
mesh_terms: D000328:Adult; D002648:Child; D003374:Coumarins / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008730:Methoxsalen / Q000627:therapeutic use; D009824:Ointments; D010789:Phototherapy; D014307:Trioxsalen / Q000008:administration & dosage / Q000627:therapeutic use*; D014820:Vitiligo / Q000188:drug therapy* / Q000628:therapy
chemical_list: D003374:Coumarins; D009824:Ointments; D008730:Methoxsalen; D014307:Trioxsalen