Evaluation of the lithium RBC/plasma ratio as a predictor of the prophylactic effect of lithium treatment in affective disorders.
62 patients with affective disorder, 31 unipolar, 22 bipolar and 9 cycloid psychotics who had received prophylactic lithium therapy for 0,3 to 7,5 years were studied. Lithium in plasma, lithium in red blood cells (RBC) and the lithium ratio (RBC/plasma) were estimated. The lithium ratio does not seem to be of predictive value in determining for which patients prophylactic lithium therapy will succeed.
D000328:Adult; D000342:Affective Symptoms / Q000188:drug therapy* / Q000517:prevention & control; D000368:Aged; D004912:Erythrocytes / Q000032:analysis*; D005260:Female; D006801:Humans; D008094:Lithium / Q000097:blood* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012008:Recurrence
D008094:Lithium