[Systolic time intervals of the left ventricle in neuromuscular diseases].
In 64 patients having neuromuscular disease and in 11 healthy persons, preejection period (PEP), ejection time index (LVETI) and PEP/LVET ratio of the left ventricle were studied by indirect method. PEP was significantly longer, ejection time index was significantly shorter and PEP/LVET ratio was significantly higher in patients with progressive muscular dystrophy than healthy persons. In 75% of patients having this disease LVETI was shortened and only in 30% of them Ecg abnormalities could be detected. These findings are postulated to be due to diffusely decreased contractility of the left ventricular heart muscle in progressive muscular dystrophy.
D000328:Adult; D000690:Amyotrophic Lateral Sclerosis / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D005621:Friedreich Ataxia / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009133:Muscular Atrophy / Q000503:physiopathology; D009136:Muscular Dystrophies / Q000503:physiopathology; D009157:Myasthenia Gravis / Q000503:physiopathology; D009200:Myocardial Contraction; D009220:Myositis / Q000503:physiopathology; D009223:Myotonic Dystrophy / Q000503:physiopathology; D009468:Neuromuscular Diseases / Q000503:physiopathology*; D013997:Time Factors
Die systolischen Zeitintervalle der linken Herzkammer bei neuromuskulären Krankheiten