Epidermal growth factor enhancement of skin tumor induction in mice.
Subcutaneous injection of epidermal growth factor 1. significantly shortened the latency period for the appearance of methylcholanthrene induced skin tumors and 2. increased the average number of papillomas elicited per mouse in both the Swiss Webster and C3HeB/FeJ strains.
D000818:Animals; D005260:Female; D006133:Growth Substances; D008748:Methylcholanthrene; D051379:Mice; D008809:Mice, Inbred C3H; D010212:Papilloma / Q000139:chemically induced; D010455:Peptides; D012878:Skin Neoplasms / Q000139:chemically induced*; D013997:Time Factors
D006133:Growth Substances; D010455:Peptides; D008748:Methylcholanthrene