The level and composition of seromucoid and nondialysable serum sugar-peptide fraction compared with the activity of galactosyl transferase (EC 2.4.1.38) of liver Golgi membranes in insulin-treated rats.
Long-term treatment of rats with insulin does not influence the yield of the Golgi membrane-rich fraction obtained by Fleischers' method or the activity of galactosyl transferase (EC 2.1.1.38) in present in this fraction. Exogenous insulin increases the total levels of the seromucoid and serum middle-weight molecular glycopeptide fraction, but does not alter the proportions of neutral sugars bound with the peptide residues of both fractions.
D000818:Animals; D002458:Cell Fractionation; D005260:Female; D005700:Galactosyltransferases / Q000378:metabolism*; D006020:Glycopeptides / Q000097:blood / Q000378:metabolism*; D006056:Golgi Apparatus / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure; D007328:Insulin / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism*; D008566:Membranes / Q000187:drug effects / Q000378:metabolism; D009929:Organ Size; D009961:Orosomucoid / Q000378:metabolism*; D051381:Rats
D006020:Glycopeptides; D007328:Insulin; D009961:Orosomucoid; D005700:Galactosyltransferases