title: Central retinal artery occlusion (reversible in sickle trait with glaucoma.
abstract: We report a case of central retinal artery occlusion in an 18-year-old black woman with sickle-trait haemoglobinopathy and acute glaucoma after hyphaema. The central retinal artery occlusion occurred immediately after treatment of the glaucoma with osmotic agents, raising the possibility that they played a precipitating role. We suggest that osmotic agents be used with extreme caution in sickle patients with glaucoma. The occlusion was treated by anterior chamber paracentesis with eventual return of good vision. The reversibility of retinal and optic nerve function after total ischaemia is discussed.
mesh_terms: D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications*; D001157:Arterial Occlusive Diseases / Q000209:etiology* / Q000628:therapy; D003907:Dexamethasone / Q000627:therapeutic use; D004322:Drainage; D005260:Female; D005901:Glaucoma / Q000150:complications* / Q000188:drug therapy; D005990:Glycerol / Q000627:therapeutic use; D006801:Humans; D008353:Mannitol / Q000627:therapeutic use; D012161:Retinal Artery; D012164:Retinal Diseases / Q000209:etiology; D012805:Sickle Cell Trait / Q000150:complications*; D014786:Vision Disorders / Q000209:etiology
chemical_list: D008353:Mannitol; D003907:Dexamethasone; D005990:Glycerol