[Stimulation of ribonuclease activity under the influence of nitrosoethylurea].
Nutrosoethyl urea-induced activation of alkaline ribonuclease was accelerated with the increase of the temperature from 22 to 32 degrees C. The reaction rate at 32 degrees C was more than 8 fold increased as compared with the control. Further increase of temperature to 42 degrees C decreased the stimulating effect of nitrosoethyl urea. The effect observed may be taken into consideration when studying a molecular mechanism of the effect of chemical mutagens on cell metabolism.
D004789:Enzyme Activation; D005038:Ethylnitrosourea; D009607:Nitrosourea Compounds; D010179:Pancreas / Q000201:enzymology; D012260:Ribonucleases; D013696:Temperature
D009607:Nitrosourea Compounds; D012260:Ribonucleases; D005038:Ethylnitrosourea
Stimuliatsiia aktivnosti ribonukleazy pod vliianiem nitrozoétilmocheviny