[Experimental inoculation of Leishmaniasis tropical from man to man (author's transl)].
Experimental transformation of leishmaniasis from man to man was demonstrated. The infection occurs through direct inoculation of the leishmania organism in the amastigote form: from an ulcer of a leishmania papule some materials were obtained and were inoculated intradermally in the thigh of one of the authors. Within weeks a red papule has developed in the place of inoculation from which the microorganisms were frequenctly demonstrated. The papule was cured spontaneously within 70 weeks under a formation of a flat pigmented scar. In the electronenmicroscopy the microorganisms were seen to be located intracellular. The microorganism had a double outer membrane, an oval nucleus, and a kinetoplast out of which (in the phlebotomus fly or in the culture) the future flagellum would be formed.
D006801:Humans; D007271:Injections, Intradermal; D007891:Leishmania / Q000648:ultrastructure; D007896:Leishmaniasis / Q000473:pathology / Q000635:transmission*; D008297:Male; D012867:Skin / Q000469:parasitology / Q000473:pathology
Experimentelle Inoculation der Leishmaniasis tropical von Mensch zu Mensch