Macular and perimacular vascular remodelling sickling haemoglobinopathies.
The posterior pole vasculature of 100 patients with different sickling haemoglobinopathies was studied prospectively over a period of three years. Various abnormalities of the posterior pole vasculature were seen in 29 per cent of the patients. Continuous remodelling of the macular and perimacular vasculature occurred. Visual acuity was variably affected and sometimes remained intact.
D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000473:pathology; D005260:Female; D005451:Fluorescein Angiography; D006445:Hemoglobin C Disease / Q000473:pathology; D006453:Hemoglobinopathies / Q000473:pathology*; D006801:Humans; D008266:Macula Lutea / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D012171:Retinal Vessels / Q000473:pathology*; D012805:Sickle Cell Trait / Q000473:pathology; D013789:Thalassemia / Q000473:pathology; D014652:Vascular Diseases / Q000175:diagnosis / Q000473:pathology; D014792:Visual Acuity; D014794:Visual Fields