Plasma cell infiltration of the conjunctiva associated with pancytopenia, dermatitis, and polyclonal gammopathy.
A 73-year-old man developed conjunctivitis, epiphora, pancytopenia, dermatitis, and a polyclonal gammopathy. Diffuse infiltration and thickening of the conjunctiva and lacrimal canaliculi by plasma cells was present. Histopathologic examination suggested a reactive, chronic inflammatory response rather than neoplasia. The patient's ocular manifestations appeared to be related to his pancytopenia, dermatitis, and polyclonal gammopathy.
D000368:Aged; D000741:Anemia, Aplastic / Q000150:complications*; D003228:Conjunctiva; D003872:Dermatitis / Q000150:complications*; D005132:Eye Manifestations; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007249:Inflammation; D008297:Male; D010950:Plasma Cells