title: Activation of histone gene transcription by nonhistone chromosomal phosphoproteins.
abstract: Hybridization analysis of RNA transcripts from HeLa S3 cell chromatin to histone complementary DNA indicates that a chromosomal phosphoprotein fraction activates transcription of histone messenger RNA sequences in vitro with chromatin from a phase in the cell cycle when histone genes are normally silent.
mesh_terms: D002455:Cell Division; D002843:Chromatin / Q000378:metabolism*; D002868:Chromosomal Proteins, Non-Histone / Q000494:pharmacology*; D005796:Genes; D006367:HeLa Cells; D006657:Histones / Q000096:biosynthesis*; D010750:Phosphoproteins / Q000494:pharmacology; D012333:RNA, Messenger / Q000096:biosynthesis*; D014158:Transcription, Genetic / Q000187:drug effects*
chemical_list: D002843:Chromatin; D002868:Chromosomal Proteins, Non-Histone; D006657:Histones; D010750:Phosphoproteins; D012333:RNA, Messenger