Peptide-bound hydroxylysine and large polypeptides related to collagen synthesis.
About 10% of the urinary hydroxylysine is linked to peptides. There is no significant difference between the excretion of peptide-bound hydroxylysine and hydroxylysine measured in the non-dialysable fraction of the urine. Non-dialysable hydroxylysine is highly glycosylated and contains mainly glucosyl-galactosyl-hydroxylysine. It is concluded that the urinary peptide-bound hydroxylysine is present in the non-dialysable collagen polypeptides. Their unusual carbohydrate composition is discussed.
D003094:Collagen / Q000096:biosynthesis; D006027:Glycosides / Q000652:urine; D006801:Humans; D006901:Hydroxylysine / Q000302:isolation & purification / Q000652:urine*; D006909:Hydroxyproline / Q000652:urine; D010455:Peptides / Q000652:urine*
D006027:Glycosides; D010455:Peptides; D006901:Hydroxylysine; D003094:Collagen; D006909:Hydroxyproline