title: Infective endocarditis as a complication of heroin use.
abstract: Infective endocarditis in heroin addicts has been reported to have a mortality as high as 85% and reports have varied widely regarding predominant valvular involvement and infecting microorganisms. A retrspective study was done and 61 cases of heroin-associated infective endocarditis were identified at Freedmen's Hospital and the District of Columbia General Hospital, Washington, DC between January 1969 and January 1973. Our results indicate that staphylococcal infection of the tricuspid valve has a much higher incidence in this population than has generally been believed and that it is the predominant presentation of infective endocarditis in these patients. The outcome of patients in our series compares favorably with previous reports and suggests that early diagnosis and prompt institution of appropriate antimicrobial therapy are important and may lead to improved survival in addicts with tricuspid endocarditis.
mesh_terms: D000293:Adolescent; D000328:Adult; D004617:Embolism / Q000150:complications; D004696:Endocarditis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D006556:Heroin Dependence / Q000150:complications*; D006801:Humans; D008297:Male; D008712:Methicillin / Q000627:therapeutic use; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000150:complications; D013203:Staphylococcal Infections / Q000150:complications*; D014262:Tricuspid Valve Insufficiency / Q000150:complications / Q000175:diagnosis
chemical_list: D008712:Methicillin