[Effect of contrical on the activity of dehydrogenases and their isoenzymes in the muscles and organs of animals with developing granulation tissue].
Studies of the influence of contrycal on condition of the enzyme systems of the muscles, liver, kidneys and heart of rats with developing granulation tissue showed contrycal, a protease inhibitor, to have a stimulating effect on the LDH and MDH activity and on their isozyme spectrum. The effect of the inhibitor was expressed in the changes occurring in the state of the enzyme system, both at the site of damage (granulations and the underlying tissue) and in a number of internal organs -- the liver and kidneys.
D000818:Animals; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006097:Granulation Tissue / Q000187:drug effects / Q000201:enzymology*; D007527:Isoenzymes / Q000378:metabolism; D007668:Kidney / Q000201:enzymology; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D008291:Malate Dehydrogenase / Q000378:metabolism*; D008297:Male; D009132:Muscles / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D011480:Protease Inhibitors; D051381:Rats
D004791:Enzyme Inhibitors; D007527:Isoenzymes; D011480:Protease Inhibitors; D007770:L-Lactate Dehydrogenase; D008291:Malate Dehydrogenase
Osobennosti vliianiia kontrikala na aktivnost' degidrogenaz i ikh izofermenty v myshtsakh i organakh zhivotnykh s razvivaiushcheisia granuliatsionnoĭ tkan'iu