Clinical trials of tonsillectomy and adenoidectomy: limitations of existing studies and a current effort to evaluate efficacy.
Indications for tonsillectomy and adenoidectomy (T&A) are both uncertain and controversial. Only five prospective clinical trials of T&A have been reported. These studies provided important data, but failed to test the efficacy of the procedures in children most affected by tonsil- and adenoid-related conditions. A study currently under way focuses on just such children and also explores related immunologic issues.
D000233:Adenoidectomy / Q000009:adverse effects; D002648:Child; D005500:Follow-Up Studies; D006801:Humans; D008199:Lymphadenitis / Q000601:surgery; D010033:Otitis Media / Q000601:surgery; D010612:Pharyngitis / Q000601:surgery; D011446:Prospective Studies; D012189:Retrospective Studies; D014068:Tonsillectomy / Q000009:adverse effects; D014069:Tonsillitis / Q000601:surgery