title: Heptachlor: toxicity to and uptake by several estuarine organisms.
abstract: Technical-grade heptachlor (65% heptachlor, 22% trans-chlordane, 2% cis-chlordane, and 2% nonachlor) was tested in 96-hr bioassays to determine its toxicity to estuarine animals. The test organisms and the 96-hr LC50 or EC50s based on measured concentrations in water) are as follows: American oyster (Crassostrea virginica), 1.5 mug/liter; pink shrimp (Penaeus duorarum), 0.11 mug/liter; grass shrimp (Palaemonetes vulgaris), 1.06 mug/liter; sheepshead minnow (Cyprinodon variegatus), 3.68 mug/liter; pinfish (Lagodon rhomboides), 3.77 mug/liter; and spot (Leiostomus xanthurus), 0.85 mug/liter. Analytical-grade heptachlor (99.8% heptachlor) and heptachlor epoxide (99%) were also studied. The analytical-grade heptachlor 96-hr LC50 for pink shrimp and spot was 0.03 mug/liter and 0.86 mug/liter, respectively, while that for pink shrimp exposed to heptachlor epoxide was 0.04 mug/liter. Heptachlor was accumulated and some metabolized to its epoxide by all animals tested. Fish and oysters accumulated heptachlor in their tissues 2,800-21,300 times the measured concentration in water; shrimp, only 200-700 times.
mesh_terms: D000818:Animals; D002706:Chlordan / Q000378:metabolism; D003530:Cyprinidae / Q000502:physiology; D033364:Decapoda / Q000378:metabolism / Q000502:physiology; D005399:Fishes / Q000378:metabolism / Q000502:physiology; D006533:Heptachlor / Q000378:metabolism / Q000633:toxicity; D006534:Heptachlor Epoxide / Q000633:toxicity; D007928:Lethal Dose 50; D010125:Ostreidae / Q000378:metabolism
chemical_list: D006534:Heptachlor Epoxide; D002706:Chlordan; D006533:Heptachlor