Kalafungin. II. Chemical transformations and the absolute configuration.
The properties of number of kalafungin derivatives and analogues are consistent with the proposed structure. The absolute stereochemistry of the three active centers was determined to be RRR by optical rotatory dispersion comparisons.
D000478:Alkylation; D000935:Antifungal Agents / Q000032:analysis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D008968:Molecular Conformation; D009285:Naphthoquinones / Q000032:analysis / Q000494:pharmacology
D000935:Antifungal Agents; D009285:Naphthoquinones