[Concentration of adenylic nucleotides and respiratory phosphorylation in the mitochondria of rats with transplanted tumors].
A study was made of adenylic mononucleotides, the process of oxydative phosphorylation and ATP-ase activity of hepatic mitochondria of rats with transplantable sarcoma 45 and Walker carcinosarcoma at various stages of tumour growtli. A reduction of the ATP levels observed in the hepatic mitochondria of tumour-bearing rats was caused, on the one hand, by suppression of its formation as a result of a partial uncoupling of the oxidative phosphorylation, and on the other hand - by intensification of its decomposition as a result of increased ATP-ase activity.
D000227:Adenine Nucleotides / Q000378:metabolism*; D000244:Adenosine Diphosphate / Q000378:metabolism; D000249:Adenosine Monophosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002279:Carcinoma 256, Walker / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000378:metabolism*; D009368:Neoplasm Transplantation; D010085:Oxidative Phosphorylation; D051381:Rats; D012513:Sarcoma, Experimental / Q000378:metabolism*; D014184:Transplantation, Homologous
D000227:Adenine Nucleotides; D000249:Adenosine Monophosphate; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate
Soderzhanie adenilovykh mononukleotidov i dykhatel'noe fosforilirovanie v mitokhondriiakh krys s perevivaemymi opukholiami