Lifespan, age changes and tumour incidence in an ageing C57BL mouse colony.
Detailed data from a colony of C57BL mice kept for research into ageing processes are given on weights of 13 organs between the ages of 6 and 30 months; pathological findings and x-ray results from animals aged 6, 24 and 30 months; age-specific tumour incidences in 24 organs in 3-month period up to 36 months of age. Results of previously published age-related studies of reproductive capacity, dental abnormalities and brain changes are summarised.
D000375:Aging; D000818:Animals; D001835:Body Weight; D001846:Bone Development; D005260:Female; D008017:Life Expectancy; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL / Q000254:growth & development / Q000502:physiology*; D009369:Neoplasms / Q000453:epidemiology / Q000662:veterinary*; D009929:Organ Size; D011247:Pregnancy; D012376:Rodent Diseases / Q000453:epidemiology*