Buccal prostaglandin E2 for induction of labour.
The administration of buccal prostaglandin E2 (PGE2) was evaluated in 30 patients; effective uterine stimulation occurred in 90 per cent of those receiving a dose of 1 mg hourly. Two patients had a prolonged contraction on a single occasion during labour. The unpleasant taste of the tablets and a high incidence of nausea and vomiting indicated that buccal prostaglandins had no advantages over other methods of administering oxytocic agents.
D000284:Administration, Oral; D000328:Adult; D005260:Female; D006801:Humans; D007749:Labor Stage, Third / Q000187:drug effects; D007751:Labor, Induced; D009325:Nausea / Q000139:chemically induced; D011247:Pregnancy; D011458:Prostaglandins E / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D014590:Uterine Contraction / Q000187:drug effects; D014839:Vomiting / Q000139:chemically induced
D011458:Prostaglandins E