[Determination of L-cystine aminopeptidase (serum oxytocinase, EC 3.4.1.2) during normal pregnancy].
It is given a method to the determination of cystine aminopeptidase activity in the serum in pregnancies. A time of few minutes is necessary for one determination. The determination is performed with a spectralphotometer or with the Reaction Rate Analyzer (LKB 8600) in using the chromogen substance 1-cystine-bis p-nitroanilide. This substance is solved in dimethylformamide. The normaly range of the 8th to the 41 th week of pregnancy is determinated in a number of 453. In twins the values were higher. The cystine aminopeptidase is nearly specifically in pregnancies and is produced in the plazenta. It is a statement of cellulary activity in the plazenta.
D000626:Aminopeptidases / Q000097:blood*; D010122:Cystinyl Aminopeptidase / Q000097:blood*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007202:Indicators and Reagents; D011247:Pregnancy; D011272:Pregnancy, Multiple
D007202:Indicators and Reagents; D000626:Aminopeptidases; D010122:Cystinyl Aminopeptidase
Zur Bestimmung der L-Cystin-Aminopeptidase (Serumoxytocinase, EC 3.4.1.2) bei normaler Schwangerschaft