Lipolytic response of "diabetic" mice (db/db) to isoproterenol and propranolol in vivo.
The genetically diabetic and obese db/db mice responded lipolytically to isoproterenol and propranolol similarly to normal mice in vivo. However, considering the large amount of triglyceride in a db/db mouse, we conclude that the in vivo response of db/db adipose tissue is deficient in magnitude.
D000818:Animals; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D007545:Isoproterenol / Q000494:pharmacology*; D008053:Lipid Mobilization / Q000187:drug effects; D051379:Mice; D008810:Mice, Inbred C57BL; D008820:Mice, Obese / Q000097:blood*; D011433:Propranolol / Q000494:pharmacology*; D013997:Time Factors
D005230:Fatty Acids, Nonesterified; D011433:Propranolol; D007545:Isoproterenol