title: [Determination of the gliotoxie and demyelinating properties of serum in organ cultures of brain in experimental allergic encephalomyelitis].
abstract: The report contains some results of a study of the blood serum taken from guinea pigs and macacus rhesus with allergic encephalomyelitis to a glyotoxic and demyelinizing effect in an organ culture of the brain in newborn rats and adult macacus rhesus. It was demonstrated that the test has a high specificity to a glyotoxic effect of the blood serum in experimental allergic encephalomyelitis and a less specificity to demyelinization in vitro. The authors describe in detail the method of studying the serum in organ brain cultures.
mesh_terms: D000208:Acute Disease; D000818:Animals; D001921:Brain / Q000276:immunology; D002908:Chronic Disease; D003711:Demyelinating Diseases / Q000209:etiology*; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology*; D006168:Guinea Pigs; D007106:Immune Sera; D008253:Macaca mulatta; D009457:Neuroglia; D009924:Organ Culture Techniques; D012008:Recurrence; D012075:Remission, Spontaneous
chemical_list: D007106:Immune Sera
vernacular_title: Opredelenie gliotoksicheskikh i demieliniziruiushchikh svoĭstv syvorotki krovi v organnoĭ kul'ture mozga pri éksperimental'nom allergicheskom éntsefalomielite