Enzymatic evidence of renal tubular damage following renal angiography.
Ligandin, a glutathione (GSH) transferase, is a protein found in proximal tubular cells as well as in other tissues. It does not occur in the urine of normal subjects; however, its presence has been detected in the urine of some patients who have undergone renal angiography. This finding suggests renal tubular cell damage due to the procedure.
D058186:Acute Kidney Injury / Q000201:enzymology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000792:Angiography / Q000009:adverse effects*; D003973:Diatrizoate / Q000031:analogs & derivatives*; D003974:Diatrizoate Meglumine / Q000009:adverse effects*; D005260:Female; D005982:Glutathione Transferase / Q000652:urine*; D006801:Humans; D007683:Kidney Tubular Necrosis, Acute / Q000201:enzymology* / Q000209:etiology / Q000652:urine; D008297:Male; D008875:Middle Aged; D012077:Renal Artery / Q000000981:diagnostic imaging*
D003973:Diatrizoate; D003974:Diatrizoate Meglumine; D005982:Glutathione Transferase