A new haemolytic assay for the second component of complement (C2) in human serum.
A new, specific haemolytic assay for C2 is described using EAC43 (Antrypol) cells and serum deficient in C4 and C2 from a patient with hereditary angio-oedema. The method is simple and the results in pathological and normal sera correlate well with those obtained using the EA and C2-deficient serum method.
D000799:Angioedema / Q000276:immunology; D002462:Cell Membrane / Q000276:immunology; D003172:Complement C1 / Q000032:analysis; D003175:Complement C2 / Q000032:analysis* / Q000172:deficiency; D003181:Complement C4 / Q000172:deficiency; D003165:Complement System Proteins / Q000032:analysis*; D004912:Erythrocytes / Q000276:immunology; D006461:Hemolysis; D006801:Humans
D003172:Complement C1; D003175:Complement C2; D003181:Complement C4; D003165:Complement System Proteins