Liquid ventilation in immature newborn rabbits.
Rabbit fetuses delivered 3 days before term were artificially ventilated with air, oxygen, or oxygenated liquid fluorocarbon for 1.5-3 h. Oxygenation, as revealed by skin colour and ECG was superior in liquid-ventilated animals. Also, liquid ventilation was less harmful to the bronchiolar epithelium and, in contrast to ventilation with gas or oxygen, did not cause the formation of hyaline membranes.
D000818:Animals; D001980:Bronchi / Q000187:drug effects; D005333:Fetus; D005466:Fluorocarbons; D006339:Heart Rate / Q000187:drug effects; D008168:Lung / Q000187:drug effects / Q000473:pathology; D010100:Oxygen / Q000494:pharmacology; D011817:Rabbits; D012119:Respiration; D012121:Respiration, Artificial; D012996:Solutions
D005466:Fluorocarbons; D012996:Solutions; D010100:Oxygen