[Post-traumatic regeneration of the epithelium of the gastric and intestinal mucous membranes of dogs].
The work was devoted to the study of the sources of reparative regeneration of the epithelium of the gastric and intestinal mucosa. A number of surgical interventions on the stomach and intestine of 1 dogs were performed for the solution of this problem. On the basis of the investigations carried out the leading role in the regeneration of the gastric and intestinal mucosa was found to be played by uninjured epithelium surrounding the area of the surgical intervention. This was confirmed by the fact that a mucosa-free intestinal pedicle graft implanted into the defect of the wall of the stomach was covered by gastric mucosa; a stomach graft devoid of own mucosa became covered with intestinal mucosa when displaced in the form of a cylindrical "insertion" into the intestinal tube; mucosa-free stomach pouch became obliterated; this could be reliably attributed to the absence of the main source of regeneration -- uninjured mucosal epithelium along the periphery of the defect. No regeneration of the epithelium of the gastric mucosa from the implanted cells was revealed; this served as an additional confirmation of the fact that regeneration under conditions of the mentioned experiments occurred on account of creeping of epithelial cells surrounding the area of the surgical intervention over the free surface of mucosa.
D000818:Animals; D004285:Dogs; D004848:Epithelium; D005753:Gastric Mucosa / Q000293:injuries*; D007413:Intestinal Mucosa / Q000293:injuries*; D012038:Regeneration
Eksperimental'noe issledovanie posttravmaticheskoĭ regeneratsii épiteliia slizistoĭ obolochki zheludka i kishechnika u sobak