[Lymphocyte stimulation of healthy probands with a "Hodgkin's HL-A type" (author's transl)].
Reported correlations between HL-A type and Hodgkin's disease suggest that genetic factors as HL-A associated immune response genes may play a role in the pathogenesis of Hodgkin's disease. Assuming that healthy individuals having a Hodgkin HL-A constellation may demonstrate impaired immune function mitogen stimulation and mixed lymphocyte reaction were carried out. However, lymphocytes of 12 persons with a Hodgkin-HL-A type did not show any abnormality in the in vitro tests when compared to a control group.
D000937:Antigen-Antibody Reactions; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006689:Hodgkin Disease / Q000276:immunology*; D006801:Humans; D007125:Immunogenetics; D008213:Lymphocyte Activation
D006680:HLA Antigens; D006649:Histocompatibility Antigens
Die Lymphocytentransformierbarkeit von Gesunden mit einer "Hodgkin-HL-A-Konstellation"