Effect of growth hormone on weight and mitochondrial protein content of rat heart.
In male rats hypophysectomy reduced the wet weight of hearts per 100 g body weight. The yield of mitochondrial protein per g heart was also decreased which is in contrast to that in liver. Adiminstration of bGH to hypophysectomized rats reversed these changes towards normal. It appears that some of the effects of growth hormone may vary in different tissues.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D013006:Growth Hormone / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects*; D008297:Male; D008931:Mitochondria, Muscle / Q000378:metabolism*; D009124:Muscle Proteins / Q000378:metabolism*; D009206:Myocardium / Q000648:ultrastructure*; D009929:Organ Size / Q000187:drug effects; D010902:Pituitary Gland / Q000502:physiology; D051381:Rats
D009124:Muscle Proteins; D013006:Growth Hormone