Consequences of radiotherapy and antineoplastic therapy for the fetus.
The consequences of radiation and antineoplastic therapy on the fetus are summarized. Animal and atom bomb studies clearly demonstrate the carcinogenic effects of radiation. Less information is available on neoplasia and neonatal malformations induced by chemotherapy, but there may be an increased risk. The delayed consequences of radiation and chemotherapy are not well known and require further study.
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000028:Abortion, Induced; D000293:Adolescent; D000328:Adult; D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D000013:Congenital Abnormalities / Q000209:etiology*; D005260:Female; D005313:Fetal Death / Q000209:etiology; D005333:Fetus / Q000187:drug effects / Q000528:radiation effects; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D051379:Mice; D009369:Neoplasms / Q000628:therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011829:Radiation Dosage; D011878:Radiotherapy / Q000009:adverse effects*; D013997:Time Factors
D000970:Antineoplastic Agents