Exercise fitness, cardiac work and blood viscosity factors in patients and normals.
A study of 41 cardiovascular patients and normals showed significant correlations between physical fitness (as expressed by a fitness index based on work output) and high shear rate blood viscosity (p less than 0.01); between the cardiac work expressed as double product (= myocardial oxygen demand) and aggregation of red cells (p less than 0.05); between the triple term of cardiac work (fitness index divided by double product) and high shear rate blood viscosity (p less than 0.005) or aggregation of red cells (p less than 0.05), in all cases correlations being negative i.e., higher cardiac work or higher fitness being related to low blood viscosity or lower aggregation of red cells. Significant differences were found between high-fitness and low-fitness groups, the high-fitness group showing from plasma viscosity (p less than 0.0005), lower fibrinogen level (p less than 0.05), and higher albumin/fibrinogen ratio (p less than 0.01).
D000328:Adult; D000368:Aged; D001809:Blood Viscosity; D002302:Cardiac Output; D002318:Cardiovascular Diseases / Q000503:physiopathology*; D002784:Cholesterol / Q000097:blood; D004903:Erythrocyte Aggregation; D005340:Fibrinogen / Q000032:analysis; D006321:Heart / Q000503:physiopathology*; D006334:Heart Function Tests; D006801:Humans; D008875:Middle Aged; D005082:Physical Exertion; D010809:Physical Fitness; D012212:Rheology; D012709:Serum Albumin / Q000032:analysis
D012709:Serum Albumin; D005340:Fibrinogen; D002784:Cholesterol