Mutagenicity studies on irradiated potatoes and chlorogenic acid; micronucleus test in rats.
The micronucleus test was used to study possible mutagenic effects of (1) Irradiated potatoes extracted (a) immediately and (b) after 24-h storage following irradiation; (2) Irradiated and unirradiated chlorogenic acid; and (3) Trenimon. It was observed that irradiated potatoes (groups 1 a, b) and chlorogenic acid (group 2) did not cause mutagenic effects in the bone-marrow cells of rats. The Trenimon group (group 3), which was used as the positive control group, did show significant mutagenic effects.
D000818:Animals; D001853:Bone Marrow / Q000648:ultrastructure; D001854:Bone Marrow Cells; D002467:Cell Nucleus / Q000187:drug effects*; D002726:Chlorogenic Acid / Q000494:pharmacology*; D004912:Erythrocytes / Q000648:ultrastructure; D005514:Food Irradiation; D008297:Male; D009153:Mutagens; D010936:Plant Extracts / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D014228:Triaziquone / Q000494:pharmacology; D014675:Vegetables / Q000528:radiation effects*
D009153:Mutagens; D010936:Plant Extracts; D002726:Chlorogenic Acid; D014228:Triaziquone