title: Stimulation of the dorsal noradrenergic dundle and field potentials in the locus coeruleus.
abstract: Field potentials were recorded from the locus coeruleus following electrical stimulation of the rat midbrain. Activation of a discrete area situated ventrolateral to the central gray evoked long-latency potentials in the locus coeruleus while stimulation of other midbrain sites did not. Damage to this discrete area resulted in a depletion of norepinephrine in the cerebral cortex suggesting that it is a segment of the dorsal noradrenergic bundle arising from the locus coeruleus.
mesh_terms: D000320:Adrenergic Fibers / Q000502:physiology*; D000818:Animals; D002552:Cerebral Ventricles / Q000502:physiology*; D005071:Evoked Potentials; D009431:Neural Conduction; D009638:Norepinephrine / Q000378:metabolism; D011149:Pons / Q000502:physiology; D051381:Rats; D013681:Tegmentum Mesencephali / Q000502:physiology
chemical_list: D009638:Norepinephrine