[Haemolytic anaemia and acute renal failure associated with cephalothin and furosemide therapy (author's transl)].
A case report is presented of a 79 year old patient with a bilateral brochopneumonia. Four days after beginning the therapy with cephalothin and furosemide an acute renal failure appeared and six days later a haemolytic anaemia was observed. The modificated Coombs test was positive. The post mortem histiological examination of the kidneys revealed cloudy swelling, necrosis of tubuli, containing protein cylinders ("chromoproteid kidney").
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000368:Aged; D000743:Anemia, Hemolytic / Q000139:chemically induced*; D001996:Bronchopneumonia / Q000188:drug therapy; D002512:Cephalothin / Q000009:adverse effects* / Q000627:therapeutic use; D003298:Coombs Test; D004342:Drug Hypersensitivity; D004359:Drug Therapy, Combination; D005260:Female; D005665:Furosemide / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans
D005665:Furosemide; D002512:Cephalothin
Hämolytische Anämie und akutes Nierenversagen unter Therapie mit Cephalotin und Furosemid