Inhibition of subcutaneous Ehrlich carcinoma by antihuman-somatotropic hormone serum of the horse as determined by the tumour-tetanus assay of the mouse.
Utilizing a quantitative tumour tetanus assay of the mouse it could be shown that antisomatotropic hormone serum of the horse exerts protective effects against solid Ehrlich carcinoma of the subcutaneous tissue and concomitantly, against tetanus mortality rates as an indicator of tumour growth. The positive correlation of the inhibitory action of antisomatotropic hormone serum against both transplantable tumour cells and subcutaneous regenerative tissue as a control lends further support to the assumption that a selective mechanism interrelates proliferative mammalian cell populations and multiplying toxinogenic clostridia, thus stimulating a new field of application of antisomatotropic hormone serum.
D000818:Animals; D000912:Antibodies, Neoplasm; D000917:Antibody Formation / Q000187:drug effects; D000918:Antibody Specificity; D002286:Carcinoma, Ehrlich Tumor / Q000276:immunology*; D013006:Growth Hormone / Q000037:antagonists & inhibitors*; D006736:Horses / Q000276:immunology*; D007106:Immune Sera / Q000494:pharmacology*; D051379:Mice; D009368:Neoplasm Transplantation; D013742:Tetanus / Q000276:immunology*
D000912:Antibodies, Neoplasm; D007106:Immune Sera; D013006:Growth Hormone