title: Interaction of pepstatin with pig pepsinogen.
abstract: In contrast with pepsin, pepsinogen does not bind pepstatin at pH values between 5.3 and 2.5. Pepsinogen is not retarded by pepstatin immobilized on to aminohexyl-Sepharose at pH5.3 or 4.1, whereas at pH3.0 activation takes place during the chromatography, with retardation of the resultant pepsin.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002846:Chromatography, Affinity; D009842:Oligopeptides; D010435:Pepsinogens; D010436:Pepstatins; D011485:Protein Binding; D013552:Swine
chemical_list: D000596:Amino Acids; D009842:Oligopeptides; D010435:Pepsinogens; D010436:Pepstatins