Solubilization of glucocerebrosidase from human placenta and demonstration of a phospholipid requirement for its catalytic activity.
D005260:Female; D005776:Gaucher Disease; D005959:Glucosidases / Q000378:metabolism*; D005962:Glucosylceramidase / Q000302:isolation & purification / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D010712:Phosphatidic Acids / Q000494:pharmacology; D010713:Phosphatidylcholines / Q000494:pharmacology; D010714:Phosphatidylethanolamines / Q000494:pharmacology; D010716:Phosphatidylinositols / Q000494:pharmacology; D010718:Phosphatidylserines / Q000494:pharmacology; D010743:Phospholipids / Q000494:pharmacology*; D010920:Placenta / Q000187:drug effects / Q000201:enzymology*; D011247:Pregnancy
D010712:Phosphatidic Acids; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010716:Phosphatidylinositols; D010718:Phosphatidylserines; D010743:Phospholipids; D005959:Glucosidases; D005962:Glucosylceramidase