Mechanisms of leucocyte migration inhibition by breast tumour cell fractions.
Leucocyte migration inhibition by autologous breast tumour cell fractions was mediated by a soluble factor synthesized and released by mononuclear leucocytes and active against migrating granulocytes. This mechanism is similar to that previously described in respect to cell-mediated sensitivity to microbial antigens. Alternative mechanisms involving directly reactive granulocytes or cytophilic antibodies were rarely operative in the migration tests.
D000912:Antibodies, Neoplasm; D001943:Breast Neoplasms / Q000276:immunology*; D002464:Cell Migration Inhibition; D005260:Female; D006098:Granulocytes / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D007962:Leukocytes / Q000187:drug effects / Q000276:immunology*; D009000:Monocytes / Q000276:immunology; D011691:Puromycin / Q000494:pharmacology
D000912:Antibodies, Neoplasm; D011691:Puromycin