title: Effect of riboflavin treatment on human red cell pyruvate kinase deficiency.
abstract: The effect of riboflavin on six patients with hemolytic anemia due to hereditary pyruvate kinase deficiency was studied. Treatment over a period of four to six months produced no significant hematologic or enzymologic changes in the variants investigated.
mesh_terms: D000746:Anemia, Hemolytic, Congenital Nonspherocytic / Q000188:drug therapy; D004912:Erythrocytes / Q000201:enzymology*; D005980:Glutathione Reductase / Q000378:metabolism; D006801:Humans; D011770:Pyruvate Kinase / Q000097:blood / Q000172:deficiency*; D012256:Riboflavin / Q000627:therapeutic use*
chemical_list: D005980:Glutathione Reductase; D011770:Pyruvate Kinase; D012256:Riboflavin