Antibody deficiency and alopecia.
Three patients are described with antibody deficiency, recurrent infections, and alopecia. One patient had congenital agammaglobulinemia; the other two patients, a brother and sister, had an incomplete antibody deficiency syndrome. The loss of hair in each patient was total; the history was typical of alopecia areata. The association of alopecia and antibody deficiency has not previously been described to our knowledge in children.
D000293:Adolescent; D000361:Agammaglobulinemia / Q000150:complications*; D000506:Alopecia Areata / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007104:Immune Adherence Reaction; D007136:Immunoglobulins / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000150:complications* / Q000175:diagnosis; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012141:Respiratory Tract Infections / Q000150:complications; D012874:Skin Diseases, Infectious / Q000150:complications; D012882:Skin Tests
D007136:Immunoglobulins