Gravimetric determination of chlorhexidine using tetraphenylborate ion.
A precise and accurate gravimetric procedure was developed for the determination of chlorhexidine diacetate, digluconate, or dihydrochloride. Sodium tetraphenylborate solution was the precipitant in an acidic medium (pH 1). Tablets containing both chlorhexidine diacetate and benzocaine also were assayed.
D001645:Biguanides / Q000032:analysis*; D001896:Boron Compounds; D011232:Chemical Precipitation; D002710:Chlorhexidine / Q000032:analysis*; D004355:Drug Stability; D007700:Kinetics; D012995:Solubility; D013607:Tablets / Q000032:analysis; D013775:Tetraphenylborate
D001645:Biguanides; D001896:Boron Compounds; D013607:Tablets; D013775:Tetraphenylborate; D002710:Chlorhexidine