title: Prosthetic reconstruction of the trachea and carina.
abstract: Twenty-six patients with tracheal stenosis owing to benign stricture and malignancy have had airway reconstruction with a molded silicone rubber prosthesis. In 8 patients the distal trachea and carina were replaced with a bifurcated graft. One individual with respiratory insufficiency could not be weaned from the respirator and died in 3 weeks. Two other patients with malignancy died 15 and 18 months following operation from disseminated cancer. The remainder are living from 1 to 5 years postoperatively. Eighteen individuals have had the trachea reconstructed with a straight graft of silicone rubber. In 5 patients with long strictures the prosthesis was invaginated into the upper and lower ends of the trachea. Thirteen individuals had circumferential resection of the airway with end-to-end anastomosis of the graft to the trachea. There was one early death from erosion of the innominate artery and 5 late deaths unrelated to the prosthesis.
mesh_terms: D000328:Adult; D001980:Bronchi / Q000601:surgery*; D001987:Bronchiectasis / Q000601:surgery; D005260:Female; D006099:Granuloma / Q000601:surgery; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D009515:New Jersey; D019736:Prostheses and Implants; D011474:Prosthesis Design; D012131:Respiratory Insufficiency / Q000401:mortality; D012833:Siloxanes; D014132:Trachea / Q000601:surgery*; D014134:Tracheal Neoplasms / Q000601:surgery; D014135:Tracheal Stenosis / Q000601:surgery
chemical_list: D012833:Siloxanes