[Prostaglandin-F-levels in human plasma during late pregnancy and labour (author's transl)].
The concentrations of prostaglandin F-equivalents were measured in peripheral plasma during labour at a cervical dilatation of 5 cm and at complete dilatation. After purification, extraction and chromatography the PGF-equivalents were measured radioimmunologically. The intraassay variation was 1.5%, the interassay variation 3.5%. The specificity for PGF was 96-98%. Logit/log transformation of the standardcurve yielded a sensitivity of the assay of 120 pg. At cervical dilatation of 5 cm PGF-equivalents varied between 1300 and 3200 pg/ml plasma. At complete dilatation values changed between 1200 and 5400 pg/ml. These fluctuations correlate timedepending to the uterine contractions recorded and may be interpreted as a result of uterine PGF-release.
D002584:Cervix Uteri; D005260:Female; D006801:Humans; D007743:Labor, Obstetric; D011247:Pregnancy; D011460:Prostaglandins F / Q000097:blood*; D011863:Radioimmunoassay; D014599:Uterus / Q000378:metabolism
D011460:Prostaglandins F
Prostaglandin-F-Spiegel im menschlichen Plasma während der späten Schwangerschaft und während der Wehentätigkeit