title: [Acute hepatic coma. Experimental study on the predictive value of clinical-chemical findings for the prognosis of acute hepatic coma].
abstract: In order to determine the validity of clinical-chemical parameters for the prognosis of hepatic failure, 28 pigs were subjected to liver ischemia for 40--160 minutes duration. The following parameters were studied: GOT, GPT, gamma-GT, LAP, LDH, GlDH, AP and isoenzymes, total bilirubin, potassium, sodium and chloride. In a statistical comparison in the surviving animals, an unexplainable increase in GlDH activity was observed. In the other clinical-chemical parameters none was seen to be of use for the prognosis for either life or death in acute hepatic failure.
mesh_terms: D000208:Acute Disease; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001663:Bilirubin / Q000097:blood; D001774:Blood Chemical Analysis; D003593:Cytoplasm / Q000201:enzymology; D006501:Hepatic Encephalopathy / Q000175:diagnosis* / Q000201:enzymology; D007527:Isoenzymes / Q000097:blood; D008099:Liver / Q000166:cytology; D008930:Mitochondria, Liver / Q000201:enzymology; D011379:Prognosis; D013552:Swine
chemical_list: D007527:Isoenzymes; D000469:Alkaline Phosphatase; D001663:Bilirubin
vernacular_title: Das akute Leberkoma. Eine experimentelle Studie zur Aussagefähigkeit klinisch-chemischer Befunde für die Prognose des akuten Leberkomas