title: [Thrombocyte lactate dehydrogenase isoenzymes in patients with ischemic stroke].
abstract: It was established that in the acute period of the ischemic stroke in the maiority of cases a change of isoenzyme structure of LDG thrombocytes was due to a decrease of LDG3 activity. In a number of patients the dominant change in the spectrum was determined by LDG and LDG4 fractions. The changes were of a stable character up to 10 weeks. LDG4 increase was characteristic of the isoenzymes spectrum in the patients with a severe development of the disease and in the patients in the remote period of the stroke. The obtained data can serve as a criterion for evaluating the adaptive changes in acute brain ischemia.
mesh_terms: D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000201:enzymology*; D001921:Brain / Q000098:blood supply*; D004796:Clinical Enzyme Tests; D006801:Humans; D007511:Ischemia / Q000097:blood*; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008875:Middle Aged; D013997:Time Factors
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
vernacular_title: Izofermenty laktatdegidrogenazy trombotsitov u bol'nykh s ishemicheskim insul'tom