[Rendu-Osler disease: apropos of 50 cases followed at the Gustave-Roussy Institute].
Rendu-Osler disease is an hereditary disease due to a predominantly antosomic heredity. The statistics given for 50 cases include 27 males 7 p. 100 of which had no familial antecedents. Clinically, Rendu-Osler disease begins in adulthood (44 p. 100) and often in late adulthood. In fact, it does not become really severe until about the age of 50 or 60. Epistaxis is the most frequent accident and proves fatal in more than 10 p. 100 of cases. Treatment of the nasal symptoms, whether this involves surgical excision followed by grafting or plesiocurietherapy using irridium wires, is very disappointing. The future alone will prove whether embolization gives more permanent results.
D000328:Adult; D000367:Age Factors; D004844:Epistaxis / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications / Q000235:genetics
La maladie de Rendu-Osler: à propos de 50 cas suivis à l'Institut Gustave-Roussy