title: Problems in management of the pregnant patient with rheumatic heart disease and valve prosthesis.
abstract: The clinical course, through pregnancy and delivery, of a 30-year-old woman with rheumatic heart disease and a prosthetic mitral valve is presented. Despite maternal development of congestive cardiac failure and atrial fibrillation, the delivery of a healthy infant was achieved. The problems encountered during pregnancy and delivery in patients with rheumatic heart disease and prosthetic valves are discussed. These include the management of long-term anticoagulant therapy, prophylaxis against rheumatic fever and subacute bacterial endocarditis, impaired cardiac function, atrial fibrillation, breast feeding, and contraception as they relate both to the mother and the fetus and infant.
mesh_terms: D000328:Adult; D001281:Atrial Fibrillation / Q000188:drug therapy; D001942:Breast Feeding; D004077:Digoxin / Q000627:therapeutic use; D004698:Endocarditis, Subacute Bacterial / Q000517:prevention & control; D005260:Female; D005333:Fetus / Q000187:drug effects; D006333:Heart Failure / Q000188:drug therapy; D006350:Heart Valve Prosthesis; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008943:Mitral Valve; D010401:Penicillin G Benzathine / Q000627:therapeutic use; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000628:therapy*; D011379:Prognosis; D012213:Rheumatic Fever / Q000517:prevention & control; D012214:Rheumatic Heart Disease / Q000628:therapy*; D013411:Sulfadiazine / Q000627:therapeutic use; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D013411:Sulfadiazine; D014859:Warfarin; D004077:Digoxin; D006493:Heparin; D010401:Penicillin G Benzathine