Methods for collecting individual components of mixed saliva: the relevance to clinical pharmacology.
Methods are described for collecting constituents of mixed saliva, viz. parotid, submandibular, monor gland and sublingual saliva and gingival fluid. Literature is cited which showed that using these techniques, few antibiotics could be found in mixed saliva or its main components but all were detected in gingival fluid. Rifamicin and clindamycin were found in all components.
D005881:Gingiva / Q000032:analysis; D006801:Humans; D007742:Labial Frenum / Q000032:analysis; D008722:Methods; D010306:Parotid Gland / Q000032:analysis; D012463:Saliva / Q000032:analysis*; D012469:Salivary Glands / Q000032:analysis*; D013048:Specimen Handling / Q000379:methods*; D013361:Sublingual Gland / Q000032:analysis; D013363:Submandibular Gland / Q000032:analysis