[Modification of the oxygen supply of the small intestine demonstrated on the ileus model].
Elevation of the intraluminar pressure of rabbit ileum lowers the oxygen supply of the bowel wall in a pressure dependent manner. After decompression local PO2 exceeds the initial values. The infusion of Rheomacrodex-Sorbit induces an increase of local PO2 in the nondistended ileum. The reaction is enhanced in the distended bowel. The application of glucagon does not influence tissue PO2 significantly in either the distended or the undistended bowel. The infusion of Rheomacrodex-Sorbit as well as decompression of the distended bowel are recommended to improve oxygen supply of bowel wall in ileus.
D000818:Animals; D004195:Disease Models, Animal; D005934:Glucagon / Q000494:pharmacology; D007415:Intestinal Obstruction / Q000378:metabolism*; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption / Q000187:drug effects*; D010313:Partial Pressure; D010952:Plasma Substitutes / Q000494:pharmacology; D011817:Rabbits
D010952:Plasma Substitutes; D005934:Glucagon; D010100:Oxygen
Die Beeinflussung der Sauerstoffversorgung des Dünndarmes im Ileusmodell