Visual sensitivity to orientation of rectangles in mice with retinal degeneration.
C3H/HeJ male mice, an inbred strain showing retinal degeneration (rd), and normal-eyed DBA/IJ male mice were studied in a task requiring discrimination of horizontally and vertically oriented rectangles. The apparatus was modified Yerkes discrimination apparatus. The mice were given 30 days of discrimination training, 10 trials/day, after which 10 more trails were given on the 31st day with positive and negative cues reversed. Both strains showed a highly significant decrease in errors during acquisition, the rd strain making significantly fewer errors than the DBA/IJ animals. Reversal of the cues brought about a sharp increase in percentage of errors.
D000818:Animals; D005556:Form Perception / Q000502:physiology*; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H / Q000502:physiology*; D008811:Mice, Inbred DBA / Q000502:physiology*; D009949:Orientation / Q000502:physiology*; D012162:Retinal Degeneration / Q000235:genetics / Q000662:veterinary; D012376:Rodent Diseases / Q000235:genetics