title: Plasma renin activity, angiotensin II, and aldosterone during intense heat stress.
abstract: Plasma renin activity (PRA), angiotensin II, and aldosterone levels, arterial blood pressure, and heart rate of six male students were investigated during and after heat stress in a sauna bath. Increased PRA, angiotensin II, and aldosterone levels were found both during and after sauna. The greatest mean increases in PRA (94.9 +/- 10.4% SE, P less than 0.005) and angiotensin II (196 +/- 54.7% SE, P less than 0.02) were observed at the end of the heat stress (at 20 min), and that in plasma aldosterone (505 +/- 209% SE, P less than 0.02) 30 min after the sauna. The heart rate roughly doubled during the heat stress and there was a transient increase followed by a decrease in systolic blood pressure and a decrease in diastolic blood pressure. This study demonstrates that intense heat stress can cause remarkable changes in the three main components of the renin-angiotensin-aldosterone system.
mesh_terms: D000328:Adult; D000450:Aldosterone / Q000097:blood*; D000804:Angiotensin II / Q000097:blood*; D001794:Blood Pressure; D001798:Blood Proteins; D003404:Creatinine / Q000097:blood; D006339:Heart Rate; D006358:Hot Temperature; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D012083:Renin / Q000097:blood*; D012964:Sodium / Q000097:blood; D013312:Stress, Physiological / Q000097:blood* / Q000503:physiopathology
chemical_list: D001798:Blood Proteins; D000804:Angiotensin II; D000450:Aldosterone; D012964:Sodium; D003404:Creatinine; D012083:Renin