[Modification of postoperative intestinal atony using caerulein. Comparative studies in the rat and man].
The effect of caerulein upon postoperative enteral paralysis was investigated in animals and men. The increase in motility effected by cerulein in rats was proved by the increase in passage demonstrated after administration of radioactive test food (51CrO4Na2 solution). A clinical survey comprising 20 patients in the postoperative period following cholecystectomy, compared to an untreated control group, confirmed our findings.
D000818:Animals; D002108:Ceruletide / Q000494:pharmacology / Q000627:therapeutic use*; D002763:Cholecystectomy; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D007410:Intestinal Diseases / Q000188:drug therapy*; D009129:Muscle Tonus / Q000187:drug effects; D010243:Paralysis / Q000188:drug therapy*; D051381:Rats
D002108:Ceruletide
Die Beeinflussung der postoperativen Darmatonie durch Caerulein. Vergleichende Untersuchungen an der Ratte und am Menschen