[Are the reciprocal sliding of protofibrils and the shortening of thick filaments during muscle contraction based on a common molecular mechanism?].
It is assumed that the back stroke of myosin bridges in a contracting fibre is determined by nucleotide binding. Then an inhibition of actomyosin dissociation can lead to the shortening of the thick filaments. Possible existence of a protein control system, suppressing this dissociation is discussed.
D000255:Adenosine Triphosphate / Q000502:physiology; D009119:Muscle Contraction; D009210:Myofibrils / Q000502:physiology*; D009218:Myosins / Q000502:physiology
D000255:Adenosine Triphosphate; D009218:Myosins
Mogut li vzaimnoe skol'zhenie protofibrill i ukorochenie tolstykh niteĭ pri myshechnom sokrashchenii osnovyvat'sia na obshchem molekuliarnom mekhanizme?