title: Digital computer processing of brain scans using principal components.
abstract: Most of the scan processing methods used to date are unable to distinguish between normal and abnormal features. This paper describes a method of constructing a particular orthogonal transform from a set of normal images, the method of principal components, which may be used selectively to filter out normal features, leaving behind abnormal features. The method has been applied to brain scans and has been implemented on a small digital computer system with magnetic disc.
mesh_terms: D001927:Brain Diseases / Q000175:diagnosis*; D003201:Computers; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D011877:Radionuclide Imaging / Q000379:methods*