[Bis(monoacylglycero)phosphate--a marker lipid of secondary lysosomes? (AUTHOR'S TRANSL)].
Rats were treated with triton, dextran, silver and iron. The lysosomal fractions from their livers were isolated and the lipids analysed. (MAG)2P could be detected in every phospholipid fraction, accounting for 6-28 per cent of the total lipid phosphorus. The composition of the fatty acids from this acidic glycerophospholipid shows an extraordinarily high amount of polyenoic fatty acids (58-82 per cent of the total), of which docosahexaenoic acid is a main compound.
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D003911:Dextrans / Q000494:pharmacology; D005227:Fatty Acids / Q000032:analysis; D005994:Glycerophosphates / Q000378:metabolism*; D007501:Iron / Q000494:pharmacology; D008099:Liver / Q000648:ultrastructure; D008247:Lysosomes / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D010743:Phospholipids / Q000032:analysis; D011092:Polyethylene Glycols / Q000494:pharmacology; D051381:Rats; D012834:Silver / Q000494:pharmacology
D003911:Dextrans; D005227:Fatty Acids; D005994:Glycerophosphates; D010743:Phospholipids; D012834:Silver; D011092:Polyethylene Glycols; D007501:Iron; D000135:Acid Phosphatase
Bis(monoacylglycerin)phosphorsäure--ein Marker-Lipid sekundärer Lysosomen