A presynaptic effect of whole venom of Dendroaspis jamesoni on the hemidiaphragm of rat.
Dendroaspis jamesoni venom in a dose of 12.5 mug/ml restricts the uptake of Ca+ leading to inhibition of release of Ach from the motor nerve terminals of the hemidiaphragms of rats.
D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism*; D003964:Diaphragm; D066298:In Vitro Techniques; D008297:Male; D009132:Muscles / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D009469:Neuromuscular Junction / Q000187:drug effects* / Q000502:physiology; D010791:Phrenic Nerve / Q000502:physiology; D051381:Rats; D012910:Snake Venoms / Q000494:pharmacology*; D013696:Temperature
D012910:Snake Venoms; D000109:Acetylcholine; D002118:Calcium