title: Skeletal lesions of the feet in diabetics and their relationship to cutaneous erythema with or without necrosis on the feet.
abstract: Seventy patients with cutaneous erythema of the feet with or without necrosis were the subjects of this investigation. Sixty-five of them had open diabetes. The glucose tolerance of the remaining five patients was altered in a diabetic direction. Twenty-seven of the 70 patients had roentgenologically demonstrable destruction in the bones of the feet. These 70 patients were compared with 61 diabetic control patients of corresponding age and duration of diabetes but without these skin lesions of the feet. Only four of the 61 control patients had destruction in the bones of the feet and all these destructions were small. Precipitating factors were identified in general for the skin lesions, the most common being cardiac decompensation. A higher frequency of precipitating factors was seen in patients with skeletal destructions than in those without. The skeletal destructions and cutaneous necrosis are supposed to be equivalent lesions, localized to different tissues in the feet. When patients presenting skin lesions of the feet in the form of distal gangrene were compared with those who had cutaneous erythema and necrosis of the feet, but no distal gangrene, no differences were found with respect to age, duration of diabetes, occurrence of precipitating factors and the occurrence of skeletal destruction. Cutaneous erythema without necrosis is understood to be incipient diabetic gangrene.
mesh_terms: D000328:Adult; D000368:Aged; D001847:Bone Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000209:etiology*; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000000981:diagnostic imaging; D003925:Diabetic Angiopathies / Q000150:complications; D003929:Diabetic Neuropathies / Q000150:complications; D004890:Erythema / Q000150:complications / Q000209:etiology*; D005260:Female; D005533:Foot Dermatoses / Q000150:complications / Q000209:etiology*; D005534:Foot Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000209:etiology*; D005734:Gangrene / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography