Comparison of etidocaine and lidocaine for obstetrical analgesia.
Etidocaine, a relatively new local anaesthetic agent, is compared with lidocaine for use in epidural anaesthesia for vaginal delivery. The parameters compared were quality of anaesthesia, dose of drug, onset and regression of sensory blockade, complete degree of motor blockade, effect on maternal blood pressure, and foetal Apgar scores at one and five minutes. The major differences between the drugs are the lower percentage of satisfactory anaesthesia with etidocaine, the much greater variability in the time of onset of complete sensory block with etidocaine as compared to lidocaine, the more profound motor block with etidocaine, and the slightly longer duration of action of this drug. It is concluded that etidocaine has no real place in epidural anaesthesia for obstetrics.
D000083:Acetanilides / Q000031:analogs & derivatives; D000293:Adolescent; D000328:Adult; D000767:Anesthesia, Epidural; D000773:Anesthesia, Obstetrical; D001034:Apgar Score; D001794:Blood Pressure / Q000187:drug effects; D005041:Etidocaine / Q000494:pharmacology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008012:Lidocaine / Q000494:pharmacology; D009043:Motor Activity / Q000187:drug effects; D011247:Pregnancy; D013997:Time Factors
D000083:Acetanilides; D008012:Lidocaine; D005041:Etidocaine