Early eye removal produces excessive bilateral branching in the rat: application of cobalt filling method.
When one eye of a rat is removed at birth, axons from the remaining eye form an excess of branches which are directed to both sides of the brain. This finding, which is based on a novel application of cobalt tracing methods, provides an explanation for previous reports of expanded uncrossed projections after early eye removal.
D000818:Animals; D013508:Ophthalmologic Surgical Procedures; D051381:Rats; D014795:Visual Pathways / Q000166:cytology / Q000254:growth & development*