title: Ion chromatography: a new technique for clinical chemistry.
abstract: Ion chromatography is a new analytical technique in which the ions to be analyzed are separated on a special pellicular ion-exchange column. Once separated, the effluent from the separating column passes into a second ion-exchange column, which removes the eluent or buffer ions from the moving phase without removing the sample ions, which are detected and measured by electrical conductivity on a background of low conductance. Trace quantities can be so determined. This technique has been applied to four biological fluids: blood serum, tissue extract, urine, and cerebrospinal fluid. It is shown to be a practical analytical tool, particularly for ions having no chromophores, such as sodium, ammonium, potassium, magensium, calcium, chloride, nitrite, phosphate, and sulfate.
mesh_terms: D002118:Calcium / Q000032:analysis; D002712:Chlorides / Q000032:analysis; D002852:Chromatography, Ion Exchange / Q000379:methods*; D004553:Electric Conductivity; D004573:Electrolytes / Q000032:analysis* / Q000097:blood / Q000134:cerebrospinal fluid / Q000652:urine; D008274:Magnesium / Q000032:analysis; D009573:Nitrites / Q000032:analysis; D010710:Phosphates / Q000032:analysis; D011188:Potassium / Q000032:analysis; D000644:Quaternary Ammonium Compounds / Q000032:analysis; D012964:Sodium / Q000032:analysis; D013431:Sulfates / Q000032:analysis
chemical_list: D002712:Chlorides; D004573:Electrolytes; D009573:Nitrites; D010710:Phosphates; D000644:Quaternary Ammonium Compounds; D013431:Sulfates; D012964:Sodium; D008274:Magnesium; D011188:Potassium; D002118:Calcium