title: Inhibition of 5'-nucleotidase by concanavalin A: evidence for localization on the outer surface of the plasma membrane.
abstract: 5'-Nucleotidase activity of rat liver plasma membrane is markedly inhibited by concanavalin A. Taken together with a unilateral pattern of labelling of concanavalin A binding sites with hemocyanin, the results indicate that an allosteric site of the enzyme is at the outer surface of the membrane.
mesh_terms: D000495:Allosteric Site; D000818:Animals; D001666:Binding Sites, Antibody; D002462:Cell Membrane / Q000032:analysis* / Q000648:ultrastructure; D003208:Concanavalin A / Q000494:pharmacology*; D006433:Hemocyanins; D009708:Nucleotidases / Q000032:analysis* / Q000037:antagonists & inhibitors; D051381:Rats
chemical_list: D003208:Concanavalin A; D006433:Hemocyanins; D009708:Nucleotidases