Influence of age and time interval between death and autopsy on dopamine and 3-methoxytyramine levels in human basal ganglia.
The caudate nuclei and putamens of 30 human brains were analyzed for dopamine and its metabolite 3-methoxytyramine, most of which was presumably formed from dopamine postmortally. It was found that dopamine and the sum (dopamine + methoxytyramine) but not methoxytyramine declined with the time interval between death and autopsy as well as with age.
D000367:Age Factors; D001479:Basal Ganglia / Q000032:analysis*; D002421:Caudate Nucleus / Q000032:analysis; D004298:Dopamine / Q000032:analysis*; D006801:Humans; D011180:Postmortem Changes; D011699:Putamen / Q000032:analysis; D013997:Time Factors; D014439:Tyramine / Q000031:analogs & derivatives / Q000032:analysis*
D004298:Dopamine; D014439:Tyramine