Absorbed radiation dose from radionuclidic impurities in several 123I-labeled radiopharmaceuticals.
The radiation dose to patients from RISA, sodium iodohippurate, and rose bengal labeled with commercially available 123I and its accompanying radioimpurities has been studied. The extra radiation dose to target organs was found to range from 29% to 97% that due to 123I alone when the radiopharmaceutical is administered at calibration time. Additional delay in the time of administration increases the relative impurity dose.
D004340:Drug Contamination; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D007465:Iodohippuric Acid; D008297:Male; D011247:Pregnancy; D011829:Radiation Dosage; D012395:Rose Bengal; D012711:Serum Albumin, Radio-Iodinated; D013997:Time Factors
D007457:Iodine Radioisotopes; D012711:Serum Albumin, Radio-Iodinated; D007465:Iodohippuric Acid; D012395:Rose Bengal