title: [Gastrin in surgery].
abstract: The clinical symptomatology of the Zollinger-Ellison-syndrome, the diagnostic treatment and the surgical procedure are reviewed. The syndrome with excessive non-regulated gastrin release from the ZE-tumor is the only form of ulcer disease with importance for the surgeon. The development of a sensitive radioimmunoassay for circulating gastrin facilitated its diagnosis. The possibility of Zollinger-Ellison-syndrome should always be considered if ulcer recur after surgical procedure by simple ulcer disease. If ulcers are located at atypical sites, if multiple ulcer are found, the diagnosis of a Zollinger-Ellison-syndrome should be established by measuring serum gastrin levels.
mesh_terms: D004381:Duodenal Ulcer / Q000209:etiology; D005743:Gastrectomy; D005755:Gastrins / Q000097:blood; D006801:Humans; D013276:Stomach Ulcer / Q000209:etiology; D015043:Zollinger-Ellison Syndrome / Q000097:blood / Q000150:complications / Q000601:surgery*
chemical_list: D005755:Gastrins
vernacular_title: Gastrin in der Chirurgie