Isolation and partial characterization of a major basic protein from rat eosinophil granules.
The rat eosinophil granule possesses a major basic protein (MBP) similar to that previously isolated from human and guinea pig eosinophils. This conclusion is based on demonstration that the major protein of the rat eosinophil granule is a low molecular weight, highly basic material with an amino acid composition similar to that of the human and guinea pig MBP.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001798:Blood Proteins / Q000302:isolation & purification*; D003545:Cysteine / Q000032:analysis; D003594:Cytoplasmic Granules / Q000032:analysis; D004804:Eosinophils / Q000032:analysis*; D008970:Molecular Weight; D051381:Rats
D000596:Amino Acids; D001798:Blood Proteins; D003545:Cysteine