Metabolism of maltose during surgery in patients with diabetes mellitus under general anesthesia.
During a surgical operation under general anesthesia, maltose was administered at a rate of 1g/kg BW to 9 diabetic and 18 non-diabetic patients. The disappearance curve of maltose from blood was similar between diabetics and non-diabetics. Blood sugar tended to rise but no significant difference was found between the two groups. Lactic acid and pyruvic acid showed a tendency toward a rise, but the change was non-significant. NEFA and uric acid failed to change. Urinary excretion of maltose was not different between diabetics and non-diabetics. After 120 min., urinary excretion of maltose was similar between the two groups, but excretion as glucose was greater in the diabetic group.
D000328:Adult; D003920:Diabetes Mellitus / Q000378:metabolism*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D005743:Gastrectomy; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007263:Infusions, Parenteral; D007773:Lactates / Q000097:blood; D008297:Male; D008320:Maltose / Q000008:administration & dosage / Q000378:metabolism*; D008875:Middle Aged; D010710:Phosphates / Q000097:blood; D011773:Pyruvates / Q000097:blood; D013312:Stress, Physiological / Q000378:metabolism; D013514:Surgical Procedures, Operative; D014527:Uric Acid / Q000097:blood
D005230:Fatty Acids, Nonesterified; D007773:Lactates; D010710:Phosphates; D011773:Pyruvates; D014527:Uric Acid; D008320:Maltose; D005947:Glucose