An ultrastructural study of the relationship between pericytes and cerebral macrophages.
We studied, with the electron microscope, the normal cerebral cortex of white rats and zones adjacent to puncture wounds. The data obtained in this study, demonstrated the passage of pericytes to the nervous tissue, after the rupture of the basal membrane, and their transformation into macrophages. We suggest the possibility of the transformation of the pericytes into microglial cells.
D000818:Animals; D002540:Cerebral Cortex / Q000293:injuries / Q000648:ultrastructure*; D003593:Cytoplasm / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D008264:Macrophages / Q000648:ultrastructure*; D051381:Rats; D012270:Ribosomes / Q000648:ultrastructure