title: Direct relationship between urinary prostaglandin E and sodium excretion in essential hypertensive patients.
abstract: Urinary prostaglandins (PGEs and PGFs), sodium and potassium were measured in 17 essentially hypertensive patients. Significant positive correlations were found between a) PGEs secreted in 24 h and sodium excreted in 24 h, b) the ratio PGEs/UnaV before and PGEs/UnaV after volume expansion and c) the ration Na/K and urinary PGEs. It was suggested that renal PGEs, potent natriuretic and diuretic substances, play an important homeostatic role in the extracellular fluid regulation, and consequently in long-term control of the arterial blood pressure.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006973:Hypertension / Q000652:urine*; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000652:urine; D011458:Prostaglandins E / Q000652:urine*; D011460:Prostaglandins F / Q000652:urine; D012964:Sodium / Q000652:urine*
chemical_list: D011458:Prostaglandins E; D011460:Prostaglandins F; D012964:Sodium; D011188:Potassium