title: Synthesis of potential mescaline antagonists.
abstract: 1-[2-(3,4,5-Trimethoxyphenyl)ethyl]-3-pyrroline, 2-(3,4,5-trimethoxybenzyl)-1,2,3,6-tetrahydropyridine, N-n-propylmescaline, N-cyclopropylmethylmescaline, and N-allylmescaline were synthesized as potential mescaline antagonists. The ability of these compounds to antagonize mescaline-induced disruption of swim behavior is also given.
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D007928:Lethal Dose 50; D008297:Male; D008635:Mescaline / Q000031:analogs & derivatives / Q000037:antagonists & inhibitors* / Q000138:chemical synthesis; D008722:Methods; D051379:Mice; D013550:Swimming; D013997:Time Factors
chemical_list: D008635:Mescaline