title: [Isoimmune antibody formation after blood transfusions].
abstract: During February 1973 to October 1974 950 inpatients of the Department of Surgery, Erlangen, were tested for the presence of iso-antibodies before and after blood transfusions. Irregular antibodies were demonstrable in 0.95% of the patients before they received a blood transfusion. In 2.73% of the cases blood transfusion resulted in sensitization with the formation of specific blood group antibodies. Identification of the 26 iso-antibodies showed a prevalence of anti-Kell and anti-E (7 cases each). In view of the frequent occurrence of these two antigens tests for their presence are advisable before a blood transfusion is given. Persons who are re-admitted to hospital should also be tested to the presence of irregular antibodies to ensure that sensitization has not occurred during the intervening period.
mesh_terms: D000017:ABO Blood-Group System; D000328:Adult; D000917:Antibody Formation; D000918:Antibody Specificity; D001803:Blood Transfusion; D003298:Coombs Test; D005260:Female; D006801:Humans; D007114:Immunization; D007518:Isoantibodies / Q000032:analysis*; D007519:Isoantigens; D008297:Male
chemical_list: D000017:ABO Blood-Group System; D007518:Isoantibodies; D007519:Isoantigens
vernacular_title: Isoimmunantikörperbildung nach Bluttransfusionen