Gas chromatographic determination of acenocoumarin in human plasma.
A method based on solvent extraction, formation of a fluorinated derivative and quantitation by gas-liquid chromatography with electron-capture detection has been developed for the determination of acenocoumarin in plasma. The specificity and sensitivity of the procedure appear to be satisfactory for drug level measurements in human plasma. Its relative simplicity permits its use in routine analysis.
D000074:Acenocoumarol / Q000097:blood*; D002849:Chromatography, Gas; D002853:Chromatography, Liquid; D002855:Chromatography, Thin Layer; D006801:Humans; D008722:Methods
D000074:Acenocoumarol