title: Methods for fitting equations with two or more non-linear parameters.
abstract: 1. Descriptions are given of two ways for fitting non-linear equations by least-squares criteria to experimental data. One depends on solving a set of non-linear simultaneous equations, and the other on Taylor's theorem. 2. It is shown that better parameter estimates result when an equation with two or more non-linear parameters is fitted to all the sets of data simultaneously than when it is fitted to each set in turn.
mesh_terms: D004798:Enzymes; D007700:Kinetics; D008954:Models, Biological; D013223:Statistics as Topic
chemical_list: D004798:Enzymes