Enhanced development of tolerance to pentobarbital by desipramine inhibition of pentobarbital metabolism.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D003891:Desipramine / Q000008:administration & dosage / Q000494:pharmacology*; D004347:Drug Interactions; D004361:Drug Tolerance; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D006899:Mixed Function Oxygenases / Q000378:metabolism; D010424:Pentobarbital / Q000008:administration & dosage / Q000378:metabolism* / Q000494:pharmacology; D051381:Rats; D012890:Sleep / Q000187:drug effects; D013997:Time Factors
D006899:Mixed Function Oxygenases; D010424:Pentobarbital; D003891:Desipramine