title: [Nephrotic syndrome after treatment with penicillamine in Wilson's disease].
abstract: In a 33-year-old man with Wilson's disease a nephrotic syndrome appeared as a severe complication under penicillamine therapy. Under strong observation and exact controls of protein in the urine, leucocytes, differential blood picture and thrombocytes after interruption of the medication and retrogression of the side-effects a retarding new stabilisation of penicillamine can take place. Other side-effects of penicillamine observed as well as control measures under a long-term treatment with penicillamine are briefly discussed.
mesh_terms: D000328:Adult; D005665:Furosemide / Q000627:therapeutic use; D006527:Hepatolenticular Degeneration / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000139:chemically induced* / Q000188:drug therapy; D010396:Penicillamine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D005665:Furosemide; D011239:Prednisolone; D010396:Penicillamine
vernacular_title: Nephrotisches Syndrom nach Penizillamintherapie beim Morbus Wilson