Colonial growth and ramihyphin A-induced changes in cell walls of Neurospora sitophila.
Colonial growth of Neurospora sitophila phenotypically induced by ramihyphin A is accompanied by marked changes in the contents of DNA, RNA and proteins in the mycelium, and in the relative proportion of hexoses in cell wall hydrolysates. The glucosamine/glucose ratio is also characteristic for colonial growth. X-ray analysis of cell walls showed that ramilhyphin A suppresses the crystalline arrangement of chitin in cell walls. A combination of microbiological, biochemical and physico-chemical methods yielded a general picture of the changes accompanying the colonial growth of Neurospora sitophila.
D000935:Antifungal Agents / Q000494:pharmacology*; D002473:Cell Wall / Q000378:metabolism / Q000648:ultrastructure; D002686:Chitin / Q000096:biosynthesis; D003461:Crystallography; D004247:DNA / Q000096:biosynthesis; D005656:Fungal Proteins / Q000096:biosynthesis; D006595:Hexosamines / Q000096:biosynthesis; D006601:Hexoses / Q000096:biosynthesis; D009491:Neurospora / Q000254:growth & development* / Q000378:metabolism / Q000648:ultrastructure; D012313:RNA / Q000096:biosynthesis
D000935:Antifungal Agents; D005656:Fungal Proteins; D006595:Hexosamines; D006601:Hexoses; D002686:Chitin; D012313:RNA; D004247:DNA