title: Severe selective IgM deficiency.
abstract: Among the primary antibody deficiency syndromes, severe selective IgM deficiency (also previously known as type V dysgammaglobulinaemia) is rare, and the majority of previous reports have indicated a fatal outcome. Three adult patients who were found to have a persistently low serum IgM are described. This deficiency was not obviously related to their presenting illness; in two of the patients, who were investigated in detail, it appeared to be of no immediate consequence.
mesh_terms: D000368:Aged; D000917:Antibody Formation; D002908:Chronic Disease; D004406:Dysgammaglobulinemia / Q000175:diagnosis*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis*; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012882:Skin Tests
chemical_list: D007070:Immunoglobulin A; D007075:Immunoglobulin M