An attempt of treatment of malignant melanoma with bovine pineal tissue.
Seven incurable patients with disseminated malignant melanoma were injected (subcutaneously, sometimes intravenously) with homogenate of bovine pineal tissue. The daily injections of large quantities of pineal tissue appeared to be harmless for patients. Many-fold injections (during 9.5 months) of large quantities of pineal tissue (up to 3950 g) in 1 of 7 cases produced certain effect on subcutaneous metastases of malignant melanoma, i.e. causing reduction and even disappearance.
D000328:Adult; D000818:Animals; D002417:Cattle; D005069:Evaluation Studies as Topic; D006801:Humans; D008297:Male; D008545:Melanoma / Q000628:therapy*; D009362:Neoplasm Metastasis; D010870:Pineal Gland / Q000378:metabolism; D012878:Skin Neoplasms / Q000628:therapy*; D014020:Tissue Extracts / Q000627:therapeutic use*
D014020:Tissue Extracts