Syndrome of depressed vital functions in the immediate post-operative period of surgical patients: some aspects of its pathogenesis.
Fifty adult male and female surgical patients (age 25--40 years) undergoing elective and emergency surgical procedures were subjected to isocapnoeic, hypocapnoeic and hypercapnoeic ventilation during anaesthesia; the PaCO2 ranged between 22--90 mm Hg. Three developed the syndrome of depressed vital functions in the post-surgical period by scoring less than 7 out of 10, the others recovered normally with complete resotration of reflex activity, consciousness and skeletomuscular tone, scoring on an average 8 out of 10 points. The role of muscle relaxant drugs in this syndrome and also the depression of the central nervous system is discussed.
D000328:Adult; D000758:Anesthesia / Q000009:adverse effects*; D002245:Carbon Dioxide / Q000097:blood; D002490:Central Nervous System / Q000187:drug effects; D003864:Depression, Chemical; D005260:Female; D006801:Humans; D008297:Male; D009125:Muscle Relaxants, Central / Q000009:adverse effects; D010313:Partial Pressure; D011183:Postoperative Complications / Q000209:etiology*; D012133:Respiratory Paralysis / Q000209:etiology*; D013577:Syndrome
D009125:Muscle Relaxants, Central; D002245:Carbon Dioxide