57Co-hematoporphyrin accumulation by experimental tumors.
The in vivo distribution of 57Co-hematoporphyrin in adenocarcinoma BW10232-bearing mice has been studied. Tumor-bearing and normal animals exhibit similar patterns of radioactivity accumulation. Twenty-four hours after the administration of the radiocompound the ratios tumor to blood and tumor to muscle indicate a potential value of this radioactive porphyrin for the detection of some types of tumor.
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D003037:Cobalt Radioisotopes; D006415:Hematoporphyrins / Q000378:metabolism*; D051379:Mice; D008810:Mice, Inbred C57BL; D009369:Neoplasms / Q000175:diagnosis*; D009374:Neoplasms, Experimental; D011877:Radionuclide Imaging
D003037:Cobalt Radioisotopes; D006415:Hematoporphyrins