title: Polymorphism and predictability at the alpha-glycerophosphate dehydrogenase locus in Colias butterflies: gradients in allele frequency within single populations.
abstract: Heterozygosity at the alpha-glycerophosphate dehydrogenase locus of five species of Colias butterflies is widespread in montane populations; alpine and lowland populations are not heterozygous. Within a single demographically characterized population of C. meadii where the population extends from alpine down into montane habitats, a marked cline in allele frequency is seen. Such within-population clines suggest the involvement of strong selection across the marked ecological interface. Thermal factors are the most likely causative agents, but associative overdominance is not excluded.
mesh_terms: D000064:Acclimatization; D000483:Alleles; D000531:Altitude; D000818:Animals; D005075:Biological Evolution; D002080:Butterflies / Q000201:enzymology*; D003120:Colorado; D003433:Crosses, Genetic; D005787:Gene Frequency; D005993:Glycerolphosphate Dehydrogenase / Q000032:analysis*; D006579:Heterozygote; D007915:Lepidoptera / Q000201:enzymology*; D011110:Polymorphism, Genetic; D013045:Species Specificity
chemical_list: D005993:Glycerolphosphate Dehydrogenase