[Changes of erythrocyte membrane lipids in ethanol induced hyperlipidemia (Zieve's syndrome) (author's transl)].
In 11 patients with alcohol-induced hyperlipemia, of whom 6 showed a Zieve Syndrome increased phospholipids, triglycerides and total cholesterol were found in the red cells stromal. The gasliquid chromatographic analysis of the phospholipid fatty acids showed increased contents of saturated and monounsaturated fatty acids C 16-C 18 smaller contents of longchain highly unsaturated fatty acids. The changes in the fatty acid pattern mainly occurred in patients with Zieve Syndrome and could be important for the mechanism of the hemolytic anemia. Theses findings could be in connexion with vitamin E deficiency.
D000328:Adult; D000743:Anemia, Hemolytic / Q000097:blood* / Q000150:complications / Q000209:etiology; D002784:Cholesterol / Q000032:analysis; D004912:Erythrocytes / Q000032:analysis*; D000431:Ethanol; D005227:Fatty Acids / Q000032:analysis; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood* / Q000139:chemically induced / Q000150:complications; D007565:Jaundice / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000032:analysis; D014280:Triglycerides / Q000032:analysis; D014811:Vitamin E Deficiency / Q000150:complications
D005227:Fatty Acids; D010743:Phospholipids; D014280:Triglycerides; D000431:Ethanol; D002784:Cholesterol
Veränderungen in den Membranlipiden der Erythrocyten bei äthanolinduzierter Hyperlipidämie (Zieve-Syndrom)