[Study of the relation between cardiac function and the tonus of resistant vessels in experimental disorder of coronary circulation].
In tests set up on dogs under morphine-chloralose anesthesia features specific for upset cardio- and hemodynamics following a primary and repeated (against the background of a preliminarily provoked myocardial infarction) acute disruption of the coronary circulation were investigated. The development of an acute ischemia of the myocardium in animals with preliminarily induced chronic disruption of the coronary circulation was shown to be attended by more intensive than in healthy dogs hemodynamic shifts and functional disorders of the heart, whereas the reflex component of the reaction, the vasodilating reactions of the peripheral vessels, in particular, proved much less marked. Possible mechanisms accounting for differences in the derangement of the cardio- and hemodynamics in primary and repeated ischemia of the myocardium are discussed.
D000208:Acute Disease; D000818:Animals; D001794:Blood Pressure; D003326:Coronary Circulation; D003327:Coronary Disease / Q000503:physiopathology*; D003331:Coronary Vessels / Q000503:physiopathology; D004285:Dogs; D006321:Heart / Q000503:physiopathology*; D014655:Vascular Resistance
Issledovanie vzaimootnosheniĭ mezhdu funktsieĭ serdtsa i tonusom rezistivnykh sosudov pri eksperimental'nom narushenii koronarnogo krovoobrashcheniia