Radioimmunoassay as an improved method for measurement of serum levels of gentamicin.
A radioimmunoassay is described for the measurement of serum concentrations of gentamicin. This radioimmunoassay is more rapid, more specific and more accurate than microbiological assays. Knowledge of serum levels of gentamicin assists the clinician in regulating drug dosage to obtain an optimal therapeutic effect, and yet avoid toxic serum levels.
D000818:Animals; D000900:Anti-Bacterial Agents; D000906:Antibodies / Q000032:analysis; D001681:Biological Assay; D003404:Creatinine / Q000097:blood; D003429:Cross Reactions; D005839:Gentamicins / Q000097:blood*; D006207:Half-Life; D006801:Humans; D007674:Kidney Diseases / Q000097:blood; D011817:Rabbits; D011863:Radioimmunoassay / Q000379:methods
D000900:Anti-Bacterial Agents; D000906:Antibodies; D005839:Gentamicins; D003404:Creatinine