title: [Treatment of malignant lid tumours by intrapalpebral injection of urea (author's transl)].
abstract: 36 malignant tumours of the eyelids (basaliomas, basal-cell carcinomas and squamous-cell carcinomas) have been treated by intrapalpebral injections of a 5% to 25% solution of urea as recommended by E.D. Danopoulos. 1.5 to 3.0 ml of the solutions were injected around the tumours twice per week. Six malignant tumours disappeared completely after a treatment of eleven months; their largest initial diameter averaged 0.53 cm. Considering the protracted treatment, the uncertainty of success, without histological examination of the excised scar tissue, and finally because of the low rate of verified success, injections of dissolved urea around malignant tumours of the eye lids cannot replace radical excision.
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy; D000287:Administration, Topical; D002280:Basal Cell Carcinoma / Q000188:drug therapy; D002281:Carcinoma, Basosquamous / Q000188:drug therapy; D005142:Eyelid Neoplasms / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D010212:Papilloma / Q000188:drug therapy; D014508:Urea / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014508:Urea
vernacular_title: Behandlung bösartiger Lidtumoren mit intrapalpebralen Injektionen von Urea