title: The quantitation of plasma phytanic acid by mass fragmentography.
abstract: Plasma phytanic acid has been quantitated by mass fragmentography after its successive reduction and derivatization to the corresponding t-butyldimethylsilyl ether. The latter was estimated by selective ion monitoring of its characteristic (M-57) ion (M/z 355). The technique has the advantage of being more rapid, specific and sensitive than existing methods, permitting the determination of phytanic acid at levels greater than 5 mug/ml plasma.
mesh_terms: D002849:Chromatography, Gas / Q000379:methods; D004537:Eicosanoic Acids / Q000097:blood*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D008832:Microchemistry; D010831:Phytanic Acid / Q000097:blood*
chemical_list: D004537:Eicosanoic Acids; D010831:Phytanic Acid