title: Clinical experience in detecting endotoxemia with the limulus test in typhoid fever and other Salmonella infections.
abstract: Semiquantitative estimates of circulating endotoxin were performed by the limulus test in patients suffering from typhoid fever and other salmonelloses. The test was positive in a large number of cases. However, no clearcut correlation was found between existence of endotoxemia, as such, and pyrexia. A correlation with recent bacteremia was found for highest levels of endotoxin activity. In minor salmonelloses a striking prevalence of positive cases was observed in the age group under one year. These findings were discussed in relation to the diagnostic and pathogenetic facets of the problem.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D004731:Endotoxins / Q000097:blood*; D005260:Female; D005334:Fever; D006737:Horseshoe Crabs; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008722:Methods; D008875:Middle Aged; D012475:Salmonella; D012480:Salmonella Infections / Q000097:blood*; D018805:Sepsis; D014115:Toxemia / Q000097:blood; D014435:Typhoid Fever / Q000097:blood*
chemical_list: D004731:Endotoxins