title: Total replacement of part of the canine urethra with lyophilized vein homografts.
abstract: Three centimeters of the urethra were replaced by lyophilized homograft veins in nine male dogs. The dogs were followed for up to 6 months with periodic urethrograms. The grafted lyophilized veins served as a guide for the ingrowing transitional cell epithelium. The graft caused very little tissue reaction and hardly any formation of fibrous tissue. The urethra was covered by transitional cell epithelium after 4 to 8 weeks, and eight of the nine dogs showed no signs of obstruction during the follow-up period.
mesh_terms: D000818:Animals; D004285:Dogs; D004847:Epithelial Cells; D005500:Follow-Up Studies; D005612:Freeze Drying; D008297:Male; D014184:Transplantation, Homologous; D014521:Urethra / Q000601:surgery*; D014680:Veins / Q000637:transplantation*