Adenylate cyclase activity in human tissues.
Adenylate cyclase activity in liver, lung, pancreas, and heart ventricle, from full-term and premature newborns has been assayed. Of all tissues studied, heart had the highest activity. Fluoride 10 mM stimulates adenylate cyclase in all tissues. Glucagon evoked a small activation of liver adenylate cyclase.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D005260:Female; D005459:Fluorides / Q000494:pharmacology; D005934:Glucagon / Q000494:pharmacology; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008099:Liver / Q000201:enzymology; D008168:Lung / Q000201:enzymology; D008297:Male; D009206:Myocardium / Q000201:enzymology; D010179:Pancreas / Q000201:enzymology; D013268:Stimulation, Chemical
D005934:Glucagon; D000262:Adenylyl Cyclases; D005459:Fluorides