A radioimmunoassay method for prednisolone: comparison with the competitive protein binding method.
Cross reactivity of prednisolone with an antiserum raised against dexamethasone-21-hemisuccinate conjugated with bovine serum albumin was utilized to develop a radioimmunoassay for prednisolone in unextracted plasma. The results are in good agreement with those obtained with a standard competitive protein binding method employing prior extraction and separation of the synthetic from endogenous steroids.
D006801:Humans; D011239:Prednisolone / Q000097:blood*; D011863:Radioimmunoassay / Q000379:methods*; D011869:Radioligand Assay
D011239:Prednisolone