Evaluation of immunodiagnostic techniques for the detection of human hydatid cyst carriers in field studies.
In a study of 662 sera from a hydatidosis endemic area, the indirect hemagglutination test based on a minimal nonspecificity criterion of positivity and the latex agglutination (LA) test were found to be suitable screening techniques for the detection of sera positive to the arc 5, diagnostic of hydatid infection. The lower nonspecificity of the LA test, its greater simplicity and its excellent correlation with the immunoelectrophoresis test suggest that it is the choice screening technique for use in field surveys or seroepidemiologic studies of hydatid disease. The advantages and limitations of this serologic approach for the detection of human hydatid cyst carriers in field studies are discussed.
D004443:Echinococcosis / Q000175:diagnosis* / Q000276:immunology; D005069:Evaluation Studies as Topic; D006386:Hemagglutination Tests; D006801:Humans; D007122:Immunoelectrophoresis; D007841:Latex Fixation Tests; D012882:Skin Tests