Development of immunity against antigens of the A and B blood groups during postembryogenesis in chickens.
51Cr-labelled erythrocytes were injected into young chicks, F1 hybrids of the inbred chicken lines, from hatching to 2 months of age. The onset of immunity was measured by means of elimination of labelled red blood cells. It was found that with the B-locus difference between donors and recipients the immune response developed from 4 days of age to the end of the first week, whereas with the A-locus difference it developed during the second week of life. The onset of immunity is delayed in inbred chickens compared to outbred chickens, because we have used one alloantigen difference.
D000017:ABO Blood-Group System; D000818:Animals; D000917:Antibody Formation; D002645:Chickens / Q000097:blood*; D002860:Chromium Radioisotopes; D004912:Erythrocytes / Q000276:immunology
D000017:ABO Blood-Group System; D002860:Chromium Radioisotopes