[Serum haptoglobin and sialic acid content and the spontaneous rosette test values as indices of the activity of the disease process in chronic glomerulonephritis].
The diagnostic significance of haptoglobin is studied as well as of sialic acid and spontaneous rosette test (SRT) and ESR as indices of the morbid process activity in 74 patients with chronic hephritis with manifested and oligospymptomatic course and in a stage of therapeutic remission and in 14 patients with acute protracted nephritis. The parallelism of the changes in all parameters studied is proved in acute protracted nephritis and in chronic nephritis with manifested course. In patients with oligosymtomatically advancing chronic nephritis, in spite of the normal values of ESR and the rest of the routine indices for determination of the morbid process activity, haptoglobin, sialic acid and SRT were established to be increased. They were hardly normalized after the advancement of a lasting therpeutic remission. That all gives grounds to the authors to think, that the significance of the studied indices for the assessment of the morbid process activity in oligosymptomatically advancing chronic glomerulonephritis, is superior, to a certain extent, to the diagnostic signficance of ESR. Their follow up in dynamics permits their application in the determination of the immunosuppressive treatment efficiency.
D000208:Acute Disease; D000328:Adult; D002908:Chronic Disease; D005260:Female; D005921:Glomerulonephritis / Q000175:diagnosis*; D006242:Haptoglobins / Q000032:analysis*; D006801:Humans; D007104:Immune Adherence Reaction; D008297:Male; D008875:Middle Aged; D009393:Nephritis / Q000175:diagnosis; D012075:Remission, Spontaneous; D012794:Sialic Acids / Q000097:blood*
D006242:Haptoglobins; D012794:Sialic Acids
Serumnoto suderzhanie na khaptoglobina i silovata kiselina i stoĭnostite na spontanniia rozeten test--pokazateli za aktivnost na bolestniia protses pri khronichniia glomerulonefrit