title: [Pathology of renal tuberculosis (author's transl)].
abstract: Introduction of specific chemotherapy and vaccination leads to a remarkable recession of renal tuberculosis in the younger age group. Renal tuberculosis is the result of a haematogenous spread of tubercle bacillus. Haematogenous spreading occurs immediately after primary infection, or, in elderly patients, in combination with recurrency of tuberculous foci in lungs and hilar-lymphnodes. Simultaneous metastasis in the skeleton, especially in the vertebrae, are observed in 30%. The incubation period between tuberculous spread and clinical manifestation of renal tuberculosis lasts several years, in the average 5-8 years, for calcareous kidneys it may last as long as 20 years and more, for tuberculous pyelitis only a few months. Today it is possible to treat renal tuberculosis with drugs (Streptomycin, PAS and INH). In 13% the cicatrisation is combined with obstruction of calices and partial hydronephrosis, in 7% with obstruction of the ureter and total hydronephrosis. Early chemotherapy may prevent the development of tuberculous hydronephrosis.
mesh_terms: D000368:Aged; D006801:Humans; D006869:Hydronephrosis / Q000209:etiology; D007668:Kidney / Q000473:pathology; D007672:Kidney Cortex / Q000473:pathology; D007673:Kidney Cortex Necrosis / Q000209:etiology; D008297:Male; D008875:Middle Aged; D013557:Switzerland; D013997:Time Factors; D014391:Tuberculosis, Miliary / Q000473:pathology; D014398:Tuberculosis, Renal / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology*; D014399:Tuberculosis, Spinal / Q000473:pathology
vernacular_title: Die pathologische Anatomie der Nierentuberkulose