A new approach to patients with suspected anaerobic postpartum pelvic infections. Transabdominal uterine aspiration for culture and metronidazole for treatment.
Oral metronidazole was given as therapy in 25 women with the clinical diagnosis of a postpartum anaerobic soft tissue pelvic infection following a vaginal delivery. There was a good clinical response in 80 per cent of these women. No anaerobic organisms resistant to metronidazole were recovered in the treatment failures. Different specimen collection techniques were evaluated, with anaerobes recovered in 4 per cent of the blood cultures, 26.3 per cent of the transabdominal endometrial aspirations, and 88 per cent of the transcervical endometrial samples. The aerobic recovery of organisms was 4 per cent from blood cultures, 15.8 per cent from transabdominal endometrial aspirations, and 96 per cent from the transcervical approach. The significance of these findings is discussed.
D000005:Abdomen; D000328:Adult; D000693:Anaerobiosis; D001419:Bacteria / Q000302:isolation & purification*; D004716:Endometritis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use*; D011247:Pregnancy; D011645:Puerperal Infection / Q000188:drug therapy / Q000382:microbiology*; D013048:Specimen Handling / Q000379:methods*
D008795:Metronidazole