Insulin secretion in migraine: influence on the blood levels of tryptophan.
The blood levels of free tryptophan, glucose and insulin were determined in different groups of patients suffering from headache, initially and after a glucose tolerance and a tolbutamide tolerance test. The control group consisted of subjects without neurological or psychiatric disturbance. A sharp drop of blood tryptophan levels was observed in migraine patients during the tolbutamide tolerance. Migraine attacks may be induced in certain subjects by a disturbance of 5-hydroxytryptamine turnover.
D001786:Blood Glucose / Q000378:metabolism; D005951:Glucose Tolerance Test; D006261:Headache / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood*; D008881:Migraine Disorders / Q000097:blood*; D014044:Tolbutamide; D014364:Tryptophan / Q000097:blood*
D001786:Blood Glucose; D007328:Insulin; D014364:Tryptophan; D014044:Tolbutamide