Tumor inhibitory agents from Vauquelinia corymbosa (Rosaceae).
The chloroform extract of Vauquelinia corymbosa Correa has shown activity against the P-388 lymphocytic leukemia test system. The constituents responsible for this activity were identified as uvaol, ursolic acid, and betulinic acid. Their identity was proven by melting point; mixed melting point; elemental analysis; IR, PMR, and mass spectra; and preparation of derivatives.
D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification*; D053978:Pentacyclic Triterpenes; D010946:Plants, Medicinal / Q000032:analysis*; D014315:Triterpenes / Q000302:isolation & purification*; D000094062:Betulinic Acid; D000097245:Ursolic Acid
D000972:Antineoplastic Agents, Phytogenic; D053978:Pentacyclic Triterpenes; D014315:Triterpenes; D000094062:Betulinic Acid; D000097245:Ursolic Acid; C013330:uvaol