[Presence of cross-reacting thymus and brain antigens in the cerebral cortex].
Rabbit antisera against antigens of mouse, rabbit, guinea pig and human whole brain cross-reacted in the cytotoxic test with the lymphocytes of the thymus, lymph nodes and the spleen of these animal species. Mouse thymocytes were most sensitive to the antibrain sera (cytotoxic index -- 63--100 per cent); cells from other mouse lymphoid organs and lymphocytes of rabbit, guinea pig and man were more resistant. Bone marrow lymphocytes were not damaged by any of these sera. The antigens which induced the cytotoxic properties of the sera were found only in the human cerebral cortex, but not in the white matter of the brain stem.
D000818:Animals; D000941:Antigens; D001853:Bone Marrow / Q000276:immunology; D001921:Brain / Q000276:immunology*; D001933:Brain Stem / Q000276:immunology; D002540:Cerebral Cortex / Q000276:immunology; D003429:Cross Reactions; D003601:Cytotoxicity Tests, Immunologic; D006168:Guinea Pigs; D006801:Humans; D008198:Lymph Nodes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D008808:Mice, Inbred CBA; D013154:Spleen / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology
D000941:Antigens
Nalichie perekrestno reagiruiushchikh antigenov timusa i mozga v kore golovnogo mozga