title: A possible new sorbent dialyser for haemodialysis.
abstract: A system is proposed for haemodialysis which involves both dialysis and adsorption. The blood compartment is separated by a membrane from a compartment containing adsorbents and ion exchangers under reduced pressure. Urea is broken down by urease adsorbed on an ion exchanger. The ammonia produced is pumped out and the rest of the unwanted substances are bound to the adsorbing materials. The geometry and principles governing the operation of the device obviate the use of circulating dialysate fluid. Preliminary results from in vitro experiments with such a system are reported and the possibility of using this system clinically is discussed.
mesh_terms: D000327:Adsorption; D000641:Ammonia; D002244:Carbon; D006801:Humans; D007474:Ion Exchange; D007688:Kidneys, Artificial / Q000295:instrumentation*; D008567:Membranes, Artificial
chemical_list: D008567:Membranes, Artificial; D002244:Carbon; D000641:Ammonia