title: Balanced translocation, impaired sperm motility, and offspring anomaly.
abstract: An infant with multiple physical abnormalities, failure to thrive, and mental deficiency, all probably due to a 22/11 chromosomal translocation is described, and the implications of inducing pregnancies in childless couples are discussed.
mesh_terms: D000328:Adult; D002869:Chromosome Aberrations; D002904:Chromosomes, Human, 21-22 and Y; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D005474:Fluoxymesterone / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D007248:Infertility, Male / Q000188:drug therapy; D008297:Male; D008655:Mesterolone / Q000627:therapeutic use; D013081:Sperm Motility / Q000187:drug effects; D014178:Translocation, Genetic
chemical_list: D008655:Mesterolone; D005474:Fluoxymesterone