Trisomy 18 and cyclopia.
A stillborn male infant with cyclopia, holoprosencephaly, extracephalic malformations, and trisomy 18 is described. The importance of chromosome studies in infants with severe congenital malformations is discussed.
D009008:Abnormalities, Severe Teratoid / Q000235:genetics* / Q000473:pathology; D001344:Autopsy; D001921:Brain / Q000473:pathology; D002902:Chromosomes, Human, 16-18; D002941:Circle of Willis / Q000473:pathology; D004027:Diencephalon / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008831:Microcephaly / Q000473:pathology; D014314:Trisomy