Familial cardiomyopathy.
Over three generations, several members of a family suffered from cardiomyopathy exhibiting, primarily, rhythm and conduction disturbances and, eventually, congestive heart failure. Certain serum enzymes (SGOT, SGPT, LDH) were elevated. The clinical examination indicated a progressive deterioration with increasing age of the patients, a more serious course in the male members of the family, and the frequent association of mental retardation.
D000293:Adolescent; D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D001145:Arrhythmias, Cardiac / Q000201:enzymology / Q000235:genetics; D001219:Aspartate Aminotransferases / Q000097:blood; D009202:Cardiomyopathies / Q000201:enzymology / Q000235:genetics*; D005260:Female; D006333:Heart Failure / Q000201:enzymology / Q000235:genetics; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012737:Sex Factors
D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase