title: Effects on venous vasomotion from the ionic content of contrast agent solutions. An investigation on microcirculation in the bat wing.
abstract: The effects on spontaneous venous vasomotion from topical application of different contrast media were investigated in the bat wing. Spontaneous venous vasomotion could be stopped either by a high osmolality of the contrast medium or by absence of cations (Na+, K+, Ca++, Mg++) in the solution. The highest contrast medium concentration (mg I/ml), which did not stop venous vasomotion, was obtained when a non-ionic contrast medium solution with low osmolality was mixed with a solution containing Na, K, Ca, Mg-salts of an ionic medium.
mesh_terms: D000818:Animals; D002685:Chiroptera; D002712:Chlorides / Q000494:pharmacology; D003287:Contrast Media / Q000494:pharmacology*; D005950:Glucose Solution, Hypertonic / Q000494:pharmacology; D008274:Magnesium / Q000494:pharmacology; D008793:Metrizamide / Q000494:pharmacology; D008794:Metrizoic Acid / Q000494:pharmacology; D008833:Microcirculation / Q000187:drug effects*; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects*; D009994:Osmolar Concentration; D011188:Potassium / Q000494:pharmacology; D012964:Sodium / Q000494:pharmacology; D014680:Veins / Q000187:drug effects*; D014921:Wings, Animal / Q000098:blood supply
chemical_list: D002712:Chlorides; D003287:Contrast Media; D005950:Glucose Solution, Hypertonic; D012964:Sodium; D008794:Metrizoic Acid; D008274:Magnesium; D008793:Metrizamide; D011188:Potassium