Photochemotherapy (PUVA) and psoriasis: comparison of 8-MOP and 8-MOP/5-MOP.
Twenty-eight psoriatic patients received PUVA treatment (psoralen and long ultraviolet irradiations. Two preparations were used; 8-methoxypsoralen and a mixture of 5-methoxypsoralen and 8-methoxypsoralen. Both gave considerable improvement, but in 6 cases the lesions reappeared after 2 to 8 weeks, in spite of maintenance treatment. In this report, photochemotherapy of psoriasis was compared, using a UVA emitting lamp, 8-MOP, and a mixture of 8-MOP and 5-methoxypsoralen (5-MOP).
D003374:Coumarins / Q000031:analogs & derivatives*; D005260:Female; D005363:Ficusin / Q000627:therapeutic use; D011564:Furocoumarins; D006801:Humans; D008297:Male; D008730:Methoxsalen / Q000627:therapeutic use*; D010789:Phototherapy; D011565:Psoriasis / Q000188:drug therapy / Q000628:therapy*; D014467:Ultraviolet Therapy
D003374:Coumarins; D011564:Furocoumarins; D005363:Ficusin; D008730:Methoxsalen