Gas-chromatographic identification of drugs in gastric aspirate samples: a rapid screening procedure for emergency toxicology.
Gastric aspirate has not been used frequently in the identification of ingested drugs. Because there is only qualitative significance in such a sample, a new method is described that facilitates identification. A 1-ml gastric aspirate sample is extracted with 100 mul of chloroform and analyzed directly by gas chromatography. Seventeen drugs commonly involved in overdose cases are included in this 25-min procedure. The gastric drug screen has been applied to more than 500 patients, and results are described.
D001463:Barbiturates / Q000032:analysis; D002849:Chromatography, Gas / Q000379:methods; D005750:Gastric Juice / Q000032:analysis*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000032:analysis; D004364:Pharmaceutical Preparations / Q000032:analysis*; D019966:Substance-Related Disorders / Q000175:diagnosis; D013997:Time Factors; D014149:Tranquilizing Agents / Q000032:analysis
D001463:Barbiturates; D006993:Hypnotics and Sedatives; D004364:Pharmaceutical Preparations; D014149:Tranquilizing Agents