title: Regression analysis of the log odds ratio: a method for retrospective studies.
abstract: Quantification of the dependence of the odds ratio on concomitant variables associated with each of several 2 X 2 tables, using a regression model proposed by Zelen [1971], is an important tool for retrospective studies in epidemiology, An "exact" analysis may be based on the conditional likelihood obtained by fixing all the marginal totals. A symptotically this approach is equivalent to use of an unconditional log-linear model. The method is used to reanalyze data reported by Kneale [1971] on the relationship between obstetric radiation and childhood cancer.
mesh_terms: D001699:Biometry; D002648:Child; D005260:Female; D005333:Fetus / Q000528:radiation effects; D006801:Humans; D008962:Models, Theoretical; D009369:Neoplasms / Q000209:etiology; D011247:Pregnancy; D011830:Radiation Effects; D011859:Radiography / Q000009:adverse effects; D012044:Regression Analysis; D012189:Retrospective Studies; D013223:Statistics as Topic