title: Surgical treatment of large ventricular septal defect with pulmonary hypertension in the first 24 months of life.
abstract: A total of 74 patients under 24 months of age with large ventricular septal defects (VSD) and pulmonary hypertension were subjected to surgical treatment from 1969 through 1975. Emergency pulmonary artery (PA) banding was performed in 13 patients during the first year of life with 1 death from postoperative respiratory failure. Primary closure of the VSD was performed in 61 patients using simple hypothermia and short-term coronary perfusion, with an operative mortality of 1.6%. There were no late deaths or neurological disturbances. Normal hemodynamic data were obtained in all 7 patients who underwent postoperative cardiac catheterization from one month to five years after the primary correction. It is concluded that primary closure of a VSD in infancy is reasonable and that PA banding is indicated only for those patients less than 6 months old with a complicated defect or in an emergency situation.
mesh_terms: D006348:Cardiac Surgical Procedures / Q000401:mortality; D006345:Heart Septal Defects, Ventricular / Q000150:complications / Q000601:surgery*; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000601:surgery*; D007036:Hypothermia, Induced; D007223:Infant; D007564:Japan; D011651:Pulmonary Artery / Q000601:surgery*