Serum isoamylases in chronic pancreatitis.
Serum isoamylases were quantitated separately in 15 patients with chronic pancreatitis. The mean activity of pancreatic isoamylase was 7 U/1 in the patients as compared to 88 U/1 in healtly controls, 8 of the patients completely lacked pancreatic isoamylase and the mean activity in the other was 15 U/1. Salivary isoamylase activities were moderately increased in the patients. Determination of the serum pancreatic isoamylase is a simple screening procedure that should be useful in the diagnosis of exocrine pancreatic insufficiency.
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006026:Glycoside Hydrolases / Q000097:blood*; D006801:Humans; D007517:Isoamylase / Q000097:blood* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000201:enzymology*; D012463:Saliva / Q000201:enzymology
D006026:Glycoside Hydrolases; D007517:Isoamylase