Haemodilution in cardiopulmonary bypass using a gelatine derivative for priming.
The effects of cardiopulmonary bypass haemodilution and a gelatine derivate for priming were evaluated by serial determinations of the acid-base and electrolyte balances, arterial oxygenation, urinary output, postoperative chest x-ray, cardiac rhythm and electrophoresis in 40 patients undergoing open heart surgery. It was noted that the priming solution used provided an excelllent buffer system to stabilize the derangements in acid-base and electrolyte balance without any side effects in oxygenation, urinary output, cardiac function or plasma proteins. The utilisation of haemodilution in cardiopulmonary bypass is discussed.
D000136:Acid-Base Equilibrium; D000293:Adolescent; D000328:Adult; D001145:Arrhythmias, Cardiac / Q000209:etiology; D001798:Blood Proteins / Q000378:metabolism; D001810:Blood Volume; D002315:Cardiopulmonary Bypass; D004573:Electrolytes / Q000097:blood; D005112:Extracorporeal Circulation; D005780:Gelatin / Q000031:analogs & derivatives*; D006344:Heart Septal Defects, Atrial / Q000503:physiopathology / Q000601:surgery*; D006400:Hematocrit; D006801:Humans; D008875:Middle Aged; D010477:Perfusion; D011183:Postoperative Complications; D014554:Urination
D001798:Blood Proteins; D004573:Electrolytes; D005780:Gelatin