title: [Experimental pain and pruritic syndromes of thalamic origin].
abstract: Pain and itch syndromes of thalamic origin were experimentally induced in rats by creation of generators of pathologically increased excitation in the gelatinose thalamic nucleus by local disturbance of the gelatinose thalamic nucleus by local distrubance of the inhibitory mechanisms in this nucleus with the aid of tetanus toxin. The latter was injected into the mentioned nucleus in the microvolumes using sterotaxis technique. The results of investigations agree with the concept of generator mechanisms of the neuropathological syndromes and the role of hyperactive determinant dispatch stations in the central nervous system activity.
mesh_terms: D000818:Animals; D001927:Brain Diseases / Q000150:complications / Q000209:etiology; D010146:Pain / Q000209:etiology*; D011537:Pruritus / Q000209:etiology*; D051381:Rats; D013577:Syndrome; D013744:Tetanus Toxin; D013787:Thalamic Nuclei
chemical_list: D013744:Tetanus Toxin
vernacular_title: Eksperimental'nye sindromy boli i zuda talamicheskogo proiskhozhdeniia