Leg ulcers in a family with both beta thalassaemia and glucose-6-phosphate dehydrogenase deficiency.
A family is presented in which the proposita, affected with thalassaemia major, developed a chronic leg ulcer at the age of 14 years. Her eldest brother, not affected with thalassaemia, had a transient leg ulcer at the age of 18 years and a second brother, affected with thalassaemia minor, developed leg ulcers when aged 15 years. Al three siblings were glucose-6-phosphate dehydrogenase deficient.
D000293:Adolescent; D005260:Female; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications*; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology* / Q000235:genetics; D008297:Male; D013789:Thalassemia / Q000150:complications*