Levels of norepinephrine in rat cerebellum after administration of the convulsant 3-mercaptopropionic acid.
The level of norepinephrine in rat cerebellum was assayed after the administration of the convulsant 3-mercaptopropionic acid. Decrease in norepinephrine was observed after the onset of seizure. The results were compared with those of GABA which were diminished both during and after convulsions. The decrease of GABA was prior to that of norepinephrine.
D000818:Animals; D002531:Cerebellum / Q000187:drug effects / Q000378:metabolism*; D003292:Convulsants / Q000494:pharmacology*; D009638:Norepinephrine / Q000378:metabolism*; D011422:Propionates / Q000494:pharmacology*; D051381:Rats; D012640:Seizures / Q000139:chemically induced / Q000378:metabolism; D013438:Sulfhydryl Compounds / Q000494:pharmacology*; D013997:Time Factors; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D003292:Convulsants; D011422:Propionates; D013438:Sulfhydryl Compounds; D005680:gamma-Aminobutyric Acid; D009638:Norepinephrine