title: [Human urinary fluoride excretion at various ages (author's transl)].
abstract: 3 groups, each consisting of 5 subjects in the following age ranges (A 4 to 6 years, B 25 to 45 years, C 60 to 70 years) were given fluoride in the form of a single dose of 6 mg. Fluoride excretion in the urine was subsequently investigated over a period of 24 hours. In a second experiment a daily dose of 6 mg of F- was given to the 3 groups over a period of 10 days. The urinary excretion was determined in 24-hour urine samples. The results are presented in two figures. 1. A time drift in urinary fluoride excretion in the direction of delayed fluoride metabolism was seen in group C subjects. 2. A periodic increase in the urinary fluoride values was also seen in these elderly subjects, indicative of an altered regulatory mechanism.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005459:Fluorides / Q000008:administration & dosage / Q000652:urine*; D006801:Humans; D008875:Middle Aged; D011199:Potentiometry; D013997:Time Factors
chemical_list: D005459:Fluorides
vernacular_title: Fluordausscheidung bei Menschen verschiedener Altersgruppen