Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste.
A patient had acute stomatitis and dermatitis due to a popular toothpaste containing cinnamon oil flavor. Cinnamon cassia oil is known as a topical sensitizer and was demonstrated to be the offending allergen. Cinnamic aldehyde and related chemicals are used widely, so that patients having cinnamon allergy may be exposed to many sources. There is difficulty in diagnosing allergic contact stomatitis.
D000447:Aldehydes / Q000009:adverse effects; D002934:Cinnamates / Q000009:adverse effects*; D003802:Dentifrices / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology*; D004342:Drug Hypersensitivity; D005421:Flavoring Agents / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D013280:Stomatitis / Q000139:chemically induced*; D014100:Toothpastes / Q000009:adverse effects*
D000447:Aldehydes; D002934:Cinnamates; D003802:Dentifrices; D005421:Flavoring Agents; D014100:Toothpastes