Induction of pneumonia in gnotobiotic calves following inoculation of Mycoplasma dispar and ureaplasmas (T-mycoplasmas).
Cloned cultures of Mycoplasma dispar and of Ureaplasma sp were inoculated endobronchially into gnotobiotic calves. The resulting pneumonia was estimated to involve 2 to 10 per cent of the lung although no clinical signs were observed. The histopathological lesions consisted of infiltration with mononuclear cells, cuffing (peribronchiolar lympho-reticular hyperplasia), catarrhal bronchiolitis and atelectasis. The results indicate that both M dispar and Ureaplasma sp are capable of causing sub-clinical cuffing pneumonia in calves.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D002417:Cattle; D002418:Cattle Diseases / Q000209:etiology* / Q000473:pathology; D005856:Germ-Free Life; D008168:Lung / Q000473:pathology; D009174:Mycoplasma / Q000276:immunology; D009175:Mycoplasma Infections / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D011014:Pneumonia / Q000473:pathology / Q000662:veterinary*; D014509:Ureaplasma / Q000276:immunology
D000907:Antibodies, Bacterial