title: Types I and II collagens in intervertebral disc. Interchanging radial distributions in annulus fibrosus.
abstract: Intervertebral disc is a highly specialized cartilaginous tissue, containing two genetic types of collagen (I and II). Analysis of peptides from a CNBr digest of collagen showed that the proportions of I and II varied gradually and inversely across pig annulus fibrosus, with exclusively type I at the extreme outer edge and exclusively type II in the nucleus pulposus.
mesh_terms: D000818:Animals; D003094:Collagen / Q000032:analysis*; D003488:Cyanogen Bromide; D007403:Intervertebral Disc / Q000032:analysis*; D010446:Peptide Fragments / Q000032:analysis; D013552:Swine
chemical_list: D010446:Peptide Fragments; D003094:Collagen; D003488:Cyanogen Bromide