title: Host--dose--time: a concept for atherosclerosis.
abstract: Advances in knowledge about atherosclerosis in the past 25 years were discussed. Areas of disagreement and agreement were identified. A concept of HOST-DOSE-TIME was introduced for the skeptical analysis of past, present, and future observation and treatment of atherosclerosis.
mesh_terms: D000367:Age Factors; D001161:Arteriosclerosis / Q000209:etiology*; D004032:Diet; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000209:etiology; D008297:Male; D008875:Middle Aged; D013315:Stress, Psychological; D013997:Time Factors