title: Steroid delivery systems for contraception.
abstract: Scientific disciplines not normally associated with pharmaceutical development have been employed to enhance the effectiveness and attractiveness of two approaches to steroidal contraception. The use of a bioerodible polymeric carrier for predictable systemic steroidal administration has removed the largest hurdle to the development of a subcutaneous contraceptive implant. A polymeric progesterone delivery system has provided a method for localizing hormonal contraception in the uterine cavity. Extensions of these technologies may provide two useful tools in limiting fertility in an already overcrowded world.
mesh_terms: D001672:Biocompatible Materials; D003267:Contraception / Q000379:methods*; D003274:Contraceptive Devices, Female / Q000379:methods*; D004343:Drug Implants; D005260:Female; D006801:Humans; D007434:Intrauterine Devices; D011374:Progesterone / Q000494:pharmacology*; D045167:Progesterone Congeners / Q000494:pharmacology*
chemical_list: D001672:Biocompatible Materials; D004343:Drug Implants; D045167:Progesterone Congeners; D011374:Progesterone