[Serum uric acid and uric acid elimination after benzbromarone therapy in patients with gout and hyperuricemia].
During treatment with benzbromaron in a dose of 100 mg/day a significant fall of uric acid was shown beginning on the second day. On the forth day in the evening or the fifth day in the morning a steady state for the uric acid level is reached. The morning value was 2,9 mg/100 ml, the evening value 2,6 mg/100 ml. During treatment, even when serum uric acid levels are decreased, an augmented renal uric acid elimination excists but a hyperuraturia was not found.
D001553:Benzbromarone / Q000627:therapeutic use*; D001572:Benzofurans / Q000627:therapeutic use*; D006073:Gout / Q000188:drug therapy / Q000378:metabolism*; D006801:Humans; D014527:Uric Acid / Q000097:blood* / Q000652:urine*
D001572:Benzofurans; D014527:Uric Acid; D001553:Benzbromarone
Serumharnsäure und Urat-Ausscheidung nach Benzbromaron-Therapie bei Patienten mit Gicht und Hyperurikämie