title: [Development of the rudimentary prostates of Ellobius lutescens (Microtinae) in organ culture; effects of androgens (author's transl)].
abstract: The structure of the rudimentary prostates of Ellobius lutescens is maintained intact after 6 days of organotypic culture in the absence of male hormones. Comparison with controls even shows a noticeable increase in the size of the epithelial cells. Adding male hormones to the culture medium does not modify the morphology of adult prostates, while it induces a sharp stimulation of immature prostates. In accordance with our previous results, these experiments show that the prostates of Ellobius lutescens lose their sensivity to androgens after puberty.
mesh_terms: D000367:Age Factors; D000728:Androgens / Q000494:pharmacology*; D015113:Androstane-3,17-diol / Q000494:pharmacology; D000818:Animals; D013196:Dihydrotestosterone / Q000494:pharmacology; D008297:Male; D009924:Organ Culture Techniques; D011467:Prostate / Q000166:cytology / Q000187:drug effects / Q000254:growth & development*; D051381:Rats; D012377:Rodentia; D013739:Testosterone / Q000494:pharmacology
chemical_list: D000728:Androgens; D013196:Dihydrotestosterone; D015113:Androstane-3,17-diol; D013739:Testosterone
vernacular_title: Evolution des prostates rudimentaires d'Ellobius lutescens (Microtinae) en culture organotypique; action des androgènes