title: [The nodular necrotizing dermatitis].
abstract: Preferring to the antecedent sparse literature an observation of "dermatitis nodularis necrotica" is described in a 15 year old girl with constipation showing the typical coarse-nodular necrotizing exanthema especially on the extremities. Histologically there was a perivasculitis with prevailing excessive cellular infiltrates (reticulum cells, granulocytes). Immunological tests (immunoelectrophoresis, fluorescence-histology in skin and intestinal biopsy) were negative. On the other hand staphylococcus aureus (as detected in skin scratches and by intracutaneous tests) seemed to play an etiologic role. Thus "dermatitis nodularis necrotica", on clinical grounds somewhat similar to papulo-necrotic tuberculids, seems to be a bacteride with secundary alterations of the skin vessels and not a variant of primary vasculitis.
mesh_terms: D000293:Adolescent; D003872:Dermatitis / Q000209:etiology / Q000382:microbiology / Q000473:pathology*; D005260:Female; D006801:Humans; D009336:Necrosis; D012867:Skin / Q000473:pathology; D013203:Staphylococcal Infections; D013211:Staphylococcus aureus
vernacular_title: Dermatitis nodularis necrotica