Diagnostic implications of the B-mitten EEG pattern: relationship to primary and secondary affective dysregulation.
Previous studies indicate that the B-Mitten EEG pattern is specific to psychiatric dysfunction and rarely encountered among normal control subjects. Our previous investigations have demonstrated a significant relationship between mittens and reactive as opposed to process schizophrenic disease. Re-analyses of mitten incidence in schizophrenics and nonschizophrenics suggests needed modification of our earlier B-Mitten-schizophrenia formulation. Present considerations indicate that the B-Mitten-reactive schizophrenia association is not primary but rather that the differential process-reactive schizophrenia mitten incidence may be a secondary epiphenomenon reflecting a more fundamental underlying process. Analyses are presented suggesting that the mitten dysrhythmia relates positively to dysphoric affective dysregulation in a manner which cuts across broad diagnostic boundaries. That the mitten pattern possibly suggests as yet unclarified subcortical dysfunction associated with symptoms of affective disturbance is a tentative hypothesis offered for consideration.
D000328:Adult; D000342:Affective Symptoms / Q000503:physiopathology*; D001714:Bipolar Disorder / Q000503:physiopathology; D001921:Brain / Q000503:physiopathology*; D003863:Depression / Q000503:physiopathology; D006801:Humans; D007046:Hysteria / Q000503:physiopathology; D008875:Middle Aged; D009497:Neurotic Disorders / Q000503:physiopathology; D010554:Personality Disorders / Q000503:physiopathology; D010698:Phobic Disorders / Q000503:physiopathology; D012559:Schizophrenia / Q000503:physiopathology; D012894:Sleep Stages / Q000502:physiology