Bone-marrow imaging in pure red blood cell aplasia.
Bone-marrow scintigraphy with indium chloride in 111 was performed on a patient with pure red blood cell aplasia before and after successful treatment with immunosuppressive drugs. The return of erythroid precursors to the bone marrow was accompanied by a substantial increase in the marrow uptake of 111In. The distribution of 111In in the posttreatment scan was indistinguishable from that of 52Fe. These results indicate that indium chloride in 111 is a useful agent for the delineation of erythroid cellularity within bone marrow.
D000328:Adult; D000741:Anemia, Aplastic / Q000175:diagnosis* / Q000188:drug therapy; D001853:Bone Marrow / Q000378:metabolism; D001854:Bone Marrow Cells; D003520:Cyclophosphamide / Q000627:therapeutic use; D004334:Drug Administration Schedule; D004905:Erythrocyte Aging / Q000187:drug effects; D004920:Erythropoiesis / Q000187:drug effects; D005260:Female; D006801:Humans; D007204:Indium / Q000378:metabolism; D007504:Iron Radioisotopes / Q000378:metabolism; D011241:Prednisone / Q000627:therapeutic use; D011868:Radioisotopes / Q000378:metabolism; D011877:Radionuclide Imaging
D007504:Iron Radioisotopes; D011868:Radioisotopes; D007204:Indium; D003520:Cyclophosphamide; D011241:Prednisone