The diffuse hypertrophy of the lower esophagus and the focal hypertrophy of the pyloric musculature in adults.
The diffuse hypertrophy of the lower esophagus is a hypertrophy and hyperplasia of the smooth muscle fibres of the M. propria, together with a distortion of the muscular architecture. The esophagogram reveals an impaired peristalsis and expansile ability of the esophagus lumen. The focal hypertrophy of the pyloric musculature in adults is a locally circumscribed hypertrophy and hyperplasia of the M. propria. The concentric pattern of the M. propria is no longer maintained. Radiologically one recognizes a benign pylorus stenosis with a complete systole and an impaired diastolic dilatation. On the basis of these macroscopical, microscopical and radiological findings both lesions differ from the circular pyloric or esophageal stenosis which occurs at the same anatomical sites. We therefore feel, that both lesions are different entities.
D000328:Adult; D003937:Diagnosis, Differential; D004935:Esophageal Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D004947:Esophagus / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia; D006984:Hypertrophy; D008297:Male; D009130:Muscle, Smooth / Q000473:pathology; D011707:Pyloric Stenosis / Q000175:diagnosis / Q000473:pathology; D011708:Pylorus / Q000473:pathology*; D011859:Radiography; D013272:Stomach Diseases / Q000000981:diagnostic imaging / Q000473:pathology*