title: [Evaluation of the changes in some laboratory parameters in liver disease patients treated with Toxepasi Complex].
abstract: Toxepasi Complex (UDPG, glutathione and vitamin B12) was administered to patients with aggressive chronic hepatitis and a second group with severe cirrhosis. Changes in laboratory enzymological data indicative of the overall extent of liver damage due to cell necrosis, cholostasis and impairment of protein synthesis were evaluated. Decreases tending to normalisation were noted two weeks after the commencement of treatment, particularly in the first group. The results suggest that the complex may be usefully employed in the management of aggressive chronic hepatitis and cirrhosis of the liver.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001797:Blood Protein Electrophoresis; D004338:Drug Combinations; D005260:Female; D005978:Glutathione / Q000627:therapeutic use*; D006505:Hepatitis / Q000188:drug therapy; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008103:Liver Cirrhosis / Q000188:drug therapy; D008107:Liver Diseases / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010088:Oxidoreductases / Q000097:blood; D000637:Transaminases / Q000097:blood; D014532:Uridine Diphosphate Glucose / Q000627:therapeutic use*; D014539:Uridine Diphosphate Sugars / Q000627:therapeutic use*; D014805:Vitamin B 12 / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D007136:Immunoglobulins; D014539:Uridine Diphosphate Sugars; D010088:Oxidoreductases; D000637:Transaminases; D005978:Glutathione; D014805:Vitamin B 12; D014532:Uridine Diphosphate Glucose
vernacular_title: Valutazione delle modificazioni di alcuni parametri di laboratorio in epato-pazienti sottoposti a trattamento con Toxepasi Complex