The lecithin/spingomyelin quotient as determined using  a modified method and human placental lactogen in the amniotic fluid.
Thirty amniotic fluid samples in late gestational age were analysed for HPL-values and the L/S-ratio. The pregnant women used in this study were healthy except three patients who developed a rh-incompatibility. The amniotic fluid was only obtained by abdominal amniocentesis. We found a decreasing tendency of the HPL-values in late pregnancy. The L/S-ratio increased. A significant correlation of both values could not be observed. In all three cases of rh-incompatibility the decrease of HPL and the increase of the L/S-ratio occurred obviously earlier and steeper. Further studies will prove the significance of these results.
D000649:Amniocentesis; D000653:Amniotic Fluid / Q000378:metabolism*; D005260:Female; D006801:Humans; D010713:Phosphatidylcholines / Q000378:metabolism*; D010928:Placental Lactogen / Q000378:metabolism*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis / Q000378:metabolism; D013109:Sphingomyelins / Q000378:metabolism*
D010713:Phosphatidylcholines; D013109:Sphingomyelins; D010928:Placental Lactogen
Der Lezithin/Sphingomyelin-Quotient, bestmmt nach einer modifizierten Methode, und HPL im Fruchtwasser