Action of methoxyflurane on intraocular pressure (IOP) and acid-basic equilibrium in the dog.
MEthoxyflurane pulmonary inhalation administered to dogs, 2 ml/10kg/5 min, after 10 minutes caused a significant increase (13.3 mmHg) in intraocular pressure as well (6 mmHg) in venous pressure and a significant fall, of 23.3 mmHg, in arterial pressure and in respiratory frequency, of 3.2 per min and amplitude of 7.1 mm. On the other side, as acid-basic equilibrium alterations in blood, were observed a fall of 0.13 of pH and an increase of 18.3 mmHg of pCO2 and of 2.7 mEq/l of bicarbonate concentration.
D000136:Acid-Base Equilibrium / Q000187:drug effects*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004285:Dogs; D005260:Female; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008733:Methoxyflurane / Q000494:pharmacology*; D012119:Respiration / Q000187:drug effects
D008733:Methoxyflurane