title: The effect of valium on myocardial blood flow.
abstract: The effect of Valium on coronary blood flow was studied. In 18 patients undergoing coronary angiography, total and regional myocardial blood flow was determined by the 133Xe wash-out technique. A total of 39 pre- and 39 post-Valium injection wash-out curves were constructed. Results indicate (99% confidence) that intravenous Valium injection (0.1 mg/kg body weight) decreases myocardial blood flow 12--15%.
mesh_terms: D000792:Angiography; D003326:Coronary Circulation / Q000187:drug effects*; D003975:Diazepam / Q000494:pharmacology*; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes; D003975:Diazepam