The desulphation of hexosamine sulphates by arylsulphatase B.
The sulphation of Carbobenzoxyglucosamine by chlorosulphonic acid resulted in formation of N-carbobenzoxyglucosamine-4,6-disulphate. UDP-galactosamine 4-sulphate and glucosamine 4,6-disulphate were the competitive inhibitors of arylsulphatase B. Arylsulphatase B can hydrolyze UDP-galactosamine 4-sulphate and glucosamine 4,6-disulphate but not galactosamine 6-sulphate.
D000818:Animals; D001192:Arylsulfatases / Q000378:metabolism*; D002417:Cattle; D003871:Dermatan Sulfate / Q000378:metabolism; D006595:Hexosamines / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D013329:Structure-Activity Relationship; D013429:Sulfatases / Q000378:metabolism*; D013431:Sulfates / Q000378:metabolism
D006595:Hexosamines; D013431:Sulfates; D003871:Dermatan Sulfate; D013429:Sulfatases; D001192:Arylsulfatases