title: GPT polymorphism in the Polish population.
abstract: In a sample of the Polish population numbering 703 subjects, three GPT types were encountered with the following frequencies: GPT1-1 0.265, GPT 2-1 0,509 and GPT 2-20.226. Frequencies of GPT1 and GPT2 genes were 0.519 and 0.481 respectively. Distribution of types in 217 mother-child pairs and in 12 families with 36 children was consistent with the hypothesis that the GPT system is dependent on a pair of codominant alleles and confirms that the GPT 1-1 and GPT 2-2 types are homozygotes, and GPT 2-1 is a heterozygote.
mesh_terms: D000328:Adult; D000410:Alanine Transaminase; D000483:Alleles; D005787:Gene Frequency; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007527:Isoenzymes; D010641:Phenotype; D011044:Poland; D011110:Polymorphism, Genetic
chemical_list: D007527:Isoenzymes; D000410:Alanine Transaminase