[Influence of strophanthin and 2,4-dinitrophenol to the scopolamine-evoked acetylcholine release in rat cortex].
In rats narcotized by urethan we investigated the effect of 2,4-dinitrophenol and ouabain with regard to the cortical release of acetylcholine stimulated by scopolamine and to the acetylcholine content of telencephalon changed in that way. Dinitrophenol increased the liberating effect of scopolamine. In the presence of dinitrophenol and scopolamine ouabain reduced acetylcholine synthesis resulting in an strong decrease of acetylcholine content on persistent diminished increase of acetylcholine release.
D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects / Q000378:metabolism*; D004140:Dinitrophenols / Q000494:pharmacology*; D008297:Male; D051381:Rats; D012601:Scopolamine / Q000494:pharmacology*; D013328:Strophanthins / Q000494:pharmacology*; D013687:Telencephalon / Q000187:drug effects / Q000378:metabolism; D014520:Urethane
D004140:Dinitrophenols; D013328:Strophanthins; D014520:Urethane; D012601:Scopolamine; D000109:Acetylcholine
Der Einfluss von Strophanthin und 2,4-Dinitrophenol auf die durch Skopolamin evozierte kortikale Azetylcholinfreisetzung der Ratte