Chronic methylphenidate effects on learning in an F2 generation.
This study investigated chronic methylphenidate effects on the learning of undrugged second generation offspring. Seventy-two albino rats were tested on avoidance conditioning. The results indicated that (a) the learning of the undrugged offspring was affected, (b) differential sex effects were obtained, and (c) some difficulty was encountered in reproduction.
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D003214:Conditioning, Classical / Q000187:drug effects*; D005260:Female; D008297:Male; D008774:Methylphenidate / Q000494:pharmacology*; D051381:Rats; D012107:Research Design; D012737:Sex Factors
D008774:Methylphenidate