title: Continuous secretin infusion with pancreozymin pretreatment as a pancreatic function test.
abstract: This paper deals with a pancreatic function test with the submaximal dose of secretin given by continuous infusion after injection of cholecystokinin-pancreozymin (CCK-PZ) in the submaximal dose. The active elimination of bladder bile by CCK-PZ pretreatment decreased the influence of biliary contamination, and the volume output and the bicarbonate concentration were stabilized by the continuous infusion of secretin. As a result, the coefficients of variation in the volume output and the bicarbonate concentration were calculated to be about 15 and about 5%, respectively. These variations were considerably smaller than those obtained in the standard secretin test. Therefore, the present study is expected to improve the diagnostic means for pancreatic excretory dysfunction.
mesh_terms: D000681:Amylases / Q000378:metabolism; D001639:Bicarbonates / Q000378:metabolism; D002766:Cholecystokinin; D005260:Female; D006801:Humans; D008297:Male; D008722:Methods; D010179:Pancreas / Q000502:physiology*; D010182:Pancreatic Diseases / Q000175:diagnosis; D012633:Secretin
chemical_list: D001639:Bicarbonates; D012633:Secretin; D002766:Cholecystokinin; D000681:Amylases