Bladder and urethral innervation in multiple sclerosis.
Bladder and urethral innervation was studied in 52 patients with multiple sclerosis using a signal tracing technique (evoked reflex latency measurement).  The majority of the patients showed prolonged signal transit times indicative of demyelinating plaques localised to the lumbosacral spinal cord.  Futhermore, impairment of the corticospinal innervation of the pudendal nucleus was found in 29 patients indicating lesions of the pyramidal tract.
D000328:Adult; D000368:Aged; D001369:Axons / Q000502:physiology; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000503:physiopathology*; D009119:Muscle Contraction; D011712:Pyramidal Tracts / Q000503:physiopathology; D013116:Spinal Cord / Q000503:physiopathology; D014521:Urethra / Q000294:innervation / Q000503:physiopathology*; D001743:Urinary Bladder / Q000294:innervation / Q000503:physiopathology*