Spectrophotometric study of complex formation between oxovanadium (IV) and antiamebic drugs.
Complex formation between oxovanadium(IV) and the antiamebic drugs 5, 7-dibromo-8-quinolinol and 5, 7-dichloro-8-quinolinol was studied in the pH 1.5-2.0 range, using ethanol, dioxane-water, and dimethylformamide as solvents. The composition of the formed complexes was determined by more than one procedure. In ethanol and dioxane-water, the 1:1 and 1:2 complexes were formed; in dimethylformamide, the 1:1, 1:2 and 1:3 complexes were formed. The stability constants were computed using two procedures: the molar ratio method and the extrapolation method. The reproducibility or results in satisfactory.
D000563:Amebicides; D055598:Chemical Phenomena; D002621:Chemistry; D006912:Hydroxyquinolines; D008433:Mathematics; D008722:Methods; D012997:Solvents; D013053:Spectrophotometry; D014639:Vanadium
D000563:Amebicides; D006912:Hydroxyquinolines; D012997:Solvents; D014639:Vanadium