Metabolic N-demethylation of nicotine. Trapping of a reactive iminium species with cyanide ion.
D000818:Animals; D003486:Cyanides / Q000378:metabolism*; D003640:Dealkylation; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism; D009538:Nicotine / Q000378:metabolism*; D000644:Quaternary Ammonium Compounds; D011817:Rabbits
D003486:Cyanides; D000644:Quaternary Ammonium Compounds; D009538:Nicotine