A model implicating the Langerhans cell in keratinocyte proliferation control.
A tentative model is presented which is based on existing data and our own cell kinetic and morphological observations in mice. The model suggests that the epidermal Langerhans cell plays a role in proliferation control of keratinocytes and may also act as an epidermal stem cell.
D000818:Animals; D002454:Cell Differentiation; D002455:Cell Division; D006801:Humans; D007633:Keratins / Q000502:physiology*; D007801:Langerhans Cells / Q000502:physiology* / Q000648:ultrastructure; D051379:Mice; D008954:Models, Biological; D012867:Skin / Q000166:cytology / Q000503:physiopathology; D012879:Skin Physiological Phenomena; D014945:Wound Healing
D007633:Keratins