title: [Histologic and immunologic study of the testis after ligation of the vas deferens in dogs].
abstract: We wanted to study the effect of bilateral ligature and section of the deferentia of 12 dogs from the histological and immunological aspects. We looked for circulating anti-sperm antibodies and anti-basal membrane of the testes antibodies at the same time as histological study to find out what happened to these lesions after epididymo-deferential anastomosis had been carried out 16 weeks later. The histological lesions (disappearance of exfoliation of the germ cells and of necrobiosis of these cells) disapperared after anastomosis. Anti-basal membrane antibodies were never found. Anti-testicular circulating auto-antibodies were never found. Anti-sperm antibodies appeared between 1 and 5 months after ligature and then disappeared a few months later. Failures to fertilise after epiddidymo-deferential anastomoses therefore do not seem to be due to these two factors.
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000032:analysis; D004285:Dogs; D006801:Humans; D008297:Male; D013094:Spermatozoa / Q000276:immunology*; D013737:Testis / Q000166:cytology / Q000276:immunology; D014659:Vasectomy
chemical_list: D001323:Autoantibodies
vernacular_title: Etude histologique wt immunologique du testicule aprés ligature des déférents chez le chien