Familial interstitial nephritis.
We report a family in whom sixteen members in three consecutive generations have died or currently suffer from chronic renal failure. Histology revealed an interstitial nephritis. One patient also had medullary cysts. The condition appears to be similar to familial juvenile nephronophthisis.
D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology / Q000648:ultrastructure; D007676:Kidney Failure, Chronic / Q000235:genetics; D008297:Male; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000235:genetics* / Q000473:pathology; D010375:Pedigree; D007690:Polycystic Kidney Diseases / Q000473:pathology