Effect of adrenergic blocing agents on peripheral noradrenaline induced thermoregulatory responses in the pigeon at heat.
1. The hyperthermic effect of intramuscular NA at 32 degrees C was abolished by propranolol but not by phentolamine preinjection. 2. The lack of hyperthermic response was at least partly due to the blocking effect of propranolol on beta-receptor mediated in heart rate. 3. After NA the respiratory rate was gradually increased in birds preinjected either with propranolol or with phentolamine.
D000818:Animals; D001833:Body Temperature Regulation / Q000187:drug effects*; D010856:Columbidae / Q000502:physiology*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006358:Hot Temperature; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology*; D010101:Oxygen Consumption / Q000187:drug effects; D010646:Phentolamine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D012119:Respiration / Q000187:drug effects; D013565:Sympatholytics / Q000494:pharmacology*
D013565:Sympatholytics; D011433:Propranolol; D009638:Norepinephrine; D010646:Phentolamine