Intestinal bypass surgery for morbid obesity. Long-term results.
Since 1962, jejunoileal bypass has been performed on 59 male and 171 female subjects, aged 18 to 55 years; these patients were followed clinically. Postoperative weight loss at two years averaged 37% in men and 35% in women. Hypokalemia (23%), hypocalcemia (22%), hypoalbuminemia (9%), metabolic acidosis (14%), elevated liver enzyme values (41%), and hyperbilirubinemia (6%), were the most commonly encountered blood chemical alterations. Complications were arthritis syndrome (men, 8%; women, 19%). urinary calculi (men, 24%; women, 10%), cholelithiasis (men, 10%; women, 9%), liver impairment (men, 2%; women, 6%), and major emotional upset (men, 8%; women, 9%). Forty-nine percent of the men and 51% of the women required rehospitalization for management of complications, surgery for hernia, anorectal disorders, nutritional support, and metabolic study. There were 19 bypass-related deaths (8%), including 10 due to liver failure.
D000293:Adolescent; D000328:Adult; D001168:Arthritis / Q000209:etiology; D001835:Body Weight; D002769:Cholelithiasis / Q000209:etiology; D005260:Female; D005414:Flatulence / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D007082:Ileum / Q000601:surgery*; D007583:Jejunum / Q000601:surgery*; D008107:Liver Diseases / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000628:therapy*; D011183:Postoperative Complications; D011247:Pregnancy; D012737:Sex Factors; D013315:Stress, Psychological; D013997:Time Factors; D014545:Urinary Calculi / Q000209:etiology; D014883:Water-Electrolyte Imbalance / Q000209:etiology