[Effect of exogenous somatotropin on the somatotropic function of the adenohypophysis in thyroidectomized rats].
Exogenic somatotropin increases the body weight gain in the inverse dependence on the taken dose and decreases the weight of the adenohypophysis in direct dependence on the dose in thyroidectomized male rats. The content of somatotropin in the adenohypophysis and incorporation of labelled amino acids into the adenohypophysis rises under the effect of exogenic somatotropin. But when the dose of the latter is increased, these indexes drop.
D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D001835:Body Weight / Q000187:drug effects*; D013006:Growth Hormone / Q000032:analysis / Q000494:pharmacology*; D008297:Male; D009929:Organ Size; D010902:Pituitary Gland / Q000187:drug effects*; D010903:Pituitary Gland, Anterior / Q000032:analysis / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D013965:Thyroidectomy
D000596:Amino Acids; D013006:Growth Hormone
Diia ekzogennoho somatotropinu na somatotropnu funktsiiu adenohipofizu tyreoïdektomovanykh schuriv