title: The influence of some antidepressant drugs on cardiac function. III. Influence on the isolated heart and isolated coronary blood vessels.
abstract: Imipramine, nortriptyline and amitriptyline reduced coronary flow in experiments on the isolated heart muscle and raised the tone of isolated coronary blood vessels.
mesh_terms: D000639:Amitriptyline / Q000494:pharmacology*; D000818:Animals; D002415:Cats; D003326:Coronary Circulation / Q000187:drug effects*; D003331:Coronary Vessels / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D006321:Heart / Q000187:drug effects*; D007099:Imipramine / Q000494:pharmacology*; D009200:Myocardial Contraction / Q000187:drug effects; D009661:Nortriptyline / Q000494:pharmacology*
chemical_list: D000639:Amitriptyline; D009661:Nortriptyline; D007099:Imipramine