Gentamicin- and cephalothin-associated rises in blood urea nitrogen.
Standardized rates of drug-attributed rises in blood urea nitrogen were 8.6%, 2.9%, and 9.3%, respectively, in patients receiving gentamicin alone, cephalothin alone, and both drugs together. These results provide evidence against a substantial synergism between the two drugs in the production of impaired renal function.
D000328:Adult; D001806:Blood Urea Nitrogen; D002512:Cephalothin / Q000009:adverse effects*; D004347:Drug Interactions; D005260:Female; D005839:Gentamicins / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged
D005839:Gentamicins; D002512:Cephalothin