title: Tritium nuclear magnetic resonance spectroscopy. Part VI (1). Tritiated steroid hormones.
abstract: The regio- and stereo-specificity of the labelling in a series of tritiated steroid hormones has been examined by 3H n.m.r., which also yields quantitative information on the distribution of the tritium between the labelled sites. Complete analysis is thus readily achieved non-destructively. Hydrogen chemical shifts for various skeletal sites are provided for the first time. The specificity of the methods of labelling steroids with tritium by catalytic reduction, catalysed exchange, and tritiodehalogenation are discussed.
mesh_terms: D000728:Androgens; D000818:Animals; D004967:Estrogens / Q000096:biosynthesis; D007553:Isotope Labeling; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D011374:Progesterone; D013237:Stereoisomerism; D013739:Testosterone / Q000378:metabolism; D014316:Tritium
chemical_list: D000728:Androgens; D004967:Estrogens; D014316:Tritium; D013739:Testosterone; D011374:Progesterone