title: [Comparative allergologic studies in treated antihypertensive patients with vasomotor rhinitis].
abstract: In order to solve the problem, whether in anti-hypertensively treated patients with the symptom of the obstructed nose allergologic mechanisms play a role, comparisons with the transformation test of lymphocytes, the serologico-nephelometric two-step method after Hoigné and the mast cell degranulation test in rats were carried out. The proof of the sensitisation to the applied medicament by the transformation test of the lymphocytes was successful in all 7 patients who complained about the symptom mentioned. These findings were supported by the positive results in 5 patients, which we achieved by means of the other two methods. By comparison with the treated and untreated control patients the question of the clinically relevant connection between sensitisation and symptomatology was discussed.
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D000959:Antihypertensive Agents / Q000009:adverse effects*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D008213:Lymphocyte Activation / Q000187:drug effects; D051381:Rats; D006255:Rhinitis, Allergic, Seasonal / Q000150:complications*
chemical_list: D000959:Antihypertensive Agents
vernacular_title: Vergleichende allergologische Untersuchungen bei antihypertensiv behandelten Patienten mit Rhinitis vasomotorica