Selective breeding for acoustic priming.
Data on eight generations of selective breeding for acoustic priming efficacy are reported. The realized heritability of this trait is approximately 0.2-0.3, indicating that the trait is determined in part by genetic factors. Animals selectively bred for acoustic priming do not differ in terms of first-trial (i.e., non-priming-induced) audiogenic seizures. These data suggest that acoustic priming and first-trial audiogenic seizures are controlled by different genetic mechanisms.
D000161:Acoustic Stimulation; D000367:Age Factors; D000818:Animals; D001947:Breeding; D005260:Female; D005796:Genes; D008297:Male; D051379:Mice; D009622:Noise; D012640:Seizures / Q000209:etiology / Q000235:genetics*; D012737:Sex Factors