[Quantitative immunochemical differentiation of creatine kinase isoenzymes. Use of antiserum to isoenzyme MM].
A possibility of quantitative differentiation of human isoenzymes of creatine kinase by using the antiserum to isoenzyme MM was studied. Rabbit antiserum to human isoenzyme MM proved to specifically inhibit its activity, without altering the isoenzyme BB activity. The use of antiserum to isoenzyme MM as a specific inhibitor makes possible differential determination of the isoenzymes of creatine-kinase or their subunits in the artificial isoenzyme mixtures, and also in the human blood serum and human tissue homogenates.
D000818:Animals; D001921:Brain / Q000201:enzymology; D003402:Creatine Kinase / Q000032:analysis* / Q000097:blood; D006801:Humans; D007106:Immune Sera; D007120:Immunochemistry / Q000379:methods; D007527:Isoenzymes / Q000032:analysis*; D009132:Muscles / Q000201:enzymology; D009203:Myocardial Infarction / Q000097:blood / Q000201:enzymology; D011817:Rabbits / Q000276:immunology
D007106:Immune Sera; D007527:Isoenzymes; D003402:Creatine Kinase