Hypertension in adult rats treated neonatally with angiotensin.
Rats treated neonatally with angiotensin showed labile hypertension in adulthood. This finding may suggest a permanently changed responsiveness of a central nervous controller of the cardiocirculatory system caused by angiotensin-induced hypertension during brain differentiation.
D000804:Angiotensin II / Q000494:pharmacology*; D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000187:drug effects / Q000254:growth & development; D005260:Female; D006973:Hypertension / Q000139:chemically induced*; D008297:Male; D051381:Rats; D012083:Renin / Q000378:metabolism
D000804:Angiotensin II; D012083:Renin