Molecular variant of factor VII.
Two patients with severe factor VII deficiency appeared to be different with respect to the presence of inactive factor VII-like material in their plasma. The inactive material, demonstrated in one patient's plasma and adsorbable onto BaSO4, inhibits the thrombotest-system and is capable of neutralizing a heterologous antibody against factor VII in a fluid phase system.
D003429:Cross Reactions; D005167:Factor VII / Q000276:immunology; D005168:Factor VII Deficiency / Q000097:blood* / Q000235:genetics; D005260:Female; D014644:Genetic Variation; D006801:Humans; D008297:Male; D009500:Neutralization Tests; D011517:Prothrombin Time
D005167:Factor VII