[Influence of aging on synthesis and breakdown of RNA and protein in the myocardium].
The rate of decomposition of RNA and proteins in the heart muscle of aged rats, as well as the effect of t-RNA on the rate of translation in the reconstructed non-cellular system of protein synthesis were studied. The rate of decomposition of sarcoplasmatic and myofibrill proteins and RNA is known to be decreased in the heart muscle of old animals. The metabolic changes. The addition of homologous t-RNA to the non-cellular system of protein synthesis was shown to stimulate the incorporation of labelled amino acids into the ribosomes of the heart of old rats.
D000375:Aging; D000818:Animals; D002474:Cell-Free System; D008297:Male; D009124:Muscle Proteins / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D014176:Protein Biosynthesis / Q000187:drug effects; D012313:RNA / Q000378:metabolism*; D012343:RNA, Transfer / Q000494:pharmacology; D051381:Rats
D009124:Muscle Proteins; D012313:RNA; D012343:RNA, Transfer
Vliianiia stareniia na sintez i raspad RNK i belkov v miokarde