title: Deoxypyrimidineuria in the course of chemotherapy in M. Hodgkin.
abstract: In patients with Hodgkin's disease the excretion of pyrimidine deoxyribonucleosides in urine was followed up within the course of 92 chemotherapeutical series with cytostatics of COOP group. In 14-day chemotherapy series, the excretion of deoxycytidine, deoxyuridine, thymidine, and their sum was significantly increased. In this paper the results are analyzed and a possibility of utilization of this finding for the judgment in the clinical course of the disease is considered.
mesh_terms: D003520:Cyclophosphamide / Q000627:therapeutic use; D003841:Deoxycytidine / Q000652:urine*; D003857:Deoxyuridine / Q000652:urine*; D004359:Drug Therapy, Combination; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy / Q000652:urine*; D006801:Humans; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D011344:Procarbazine / Q000627:therapeutic use; D012737:Sex Factors; D013156:Splenectomy; D013936:Thymidine / Q000652:urine*; D014747:Vinblastine / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D003841:Deoxycytidine; D011344:Procarbazine; D014750:Vincristine; D014747:Vinblastine; D003520:Cyclophosphamide; D011241:Prednisone; D013936:Thymidine; D003857:Deoxyuridine