HL-A8 and the immune response to various antigens.
The possession of the histocompatibility antigen HL-A8 has been correlated with serum levels of antibodies to gluten and a variety of other dietary, viral, and bacterial antigens and autoantigens. The only significant correlation with HL-A8 was of raised levels of gluten antibody. Thus it seems that HL-A8 may be associated with an enhanced immune response specifically to gluten, and not with a generally enhanced immunological responsiveness as has been suggested.
D000818:Animals; D000917:Antibody Formation; D000937:Antigen-Antibody Reactions; D000941:Antigens; D002908:Chronic Disease; D004529:Egg White; D005983:Glutens / Q000276:immunology; D006680:HLA Antigens / Q000032:analysis*; D006649:Histocompatibility Antigens / Q000032:analysis*; D006801:Humans; D008107:Liver Diseases / Q000276:immunology; D008892:Milk / Q000276:immunology
D000941:Antigens; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D005983:Glutens