The effect of an anorectic agent (Mazindol) on control of obese diabetics.
The use of an anorectic drug (mazindol) did not significantly interfere with the therapy needed to maintain control in obese diabetics. In two of four insulin-requiring patients, a reduction of the insulin requirement occurred when weight was lost. No change was needed in oral hypoglycaemic therapy in the six weeks of the trial.
D000328:Adult; D000368:Aged; D003920:Diabetes Mellitus / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007211:Indoles / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use; D008454:Mazindol / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D009765:Obesity; D010919:Placebos
D007004:Hypoglycemic Agents; D007211:Indoles; D007328:Insulin; D010919:Placebos; D008454:Mazindol