title: Factor V in an industrial population.
abstract: Factor-V levels have been measured in a random sample of 626 men and 307 women working in a variety of occupations in North West London. The method is an automated one-stage assay using the same batch of freeze-dried thromboplastin, all results being expressed in terms of the same freeze-dried standard plasma; it has been shown that only one dilution of test plasma is necessary. Factor-V levels are significantly higher when venepuncture is difficult than when it is satisfactory, the mean levels being about 130% and 117% respectively. Factor-V levels are approximately normally distributed; they are similar in men and women and in blacks and whites, and increase significantly with age at the rate of about 0.6% per annum. Factor-V levels are not affected by oral contraceptives or the menopause, and there are no differences according to blood group or secretor status.
mesh_terms: D000328:Adult; D000375:Aging; D044383:Black People; D001815:Bloodletting; D005165:Factor V / Q000032:analysis*; D005260:Female; D006801:Humans; D007221:Industry; D008131:London; D008297:Male; D008875:Middle Aged; D011153:Population; D012016:Reference Values; D012737:Sex Factors
chemical_list: D005165:Factor V