[The different cells forming granulomas: morphologic features, origin, function and development].
Granulomas consist of an aggregation of lymphocytes and of phagocytes (polynuclear and histiomonocytes) around a tissular lesion. The cells are provided by the blood and/or the lymph. Other cells develop in the focus. Within the granuloma appear other cells which derive from the previous ones, viz immunoblasts, plasmocytes, macrophages, epithelioid and giant cells. These elements cooperate to destroy the invading agent. Mastocytes, fibroblasts and myofibroblasts join in. In the granuloma these latter give rise to scarring.
D000818:Animals; D002921:Cicatrix / Q000276:immunology; D006099:Granuloma / Q000473:pathology*; D008214:Lymphocytes / Q000276:immunology; D010586:Phagocytes / Q000276:immunology; D014945:Wound Healing
Les différentes cellules constituant les granulomes. Aspect morphologique, origine, fonctions et devenir