Ultrastructure of an ovotestis in a case of true hermaphroditism.
A case of true hermaphroditism with bilateral ovotestes is reported. The karyotype was 46, XX. At laparotomy done at the age of 21 months a uterus, bilateral fallopian tubes, and bilateral gonads were observed. On frozen section examination, each gonad was shown to be an ovotestis. By light and electron microscopy, the only cellular abnormality observed in the ovotestes was the absence of primitive germ cells in the seminiferous tubules. The ovarian portion showed primordial follicles and normal follicular development.
D012734:Disorders of Sex Development / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D007985:Leydig Cells / Q000473:pathology; D008297:Male; D010053:Ovary / Q000648:ultrastructure*; D013737:Testis / Q000648:ultrastructure*