title: [The effect of the combination pramiverine/metamizole in colic pain (author's transl)].
abstract: A combination of 4,4-diphenyl-N-isopropyl-cyclohexylamine-hydrochloride (pramiverine, Sistalgin) and N-methyl-N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-aminomethanesulfonate (metamizole) (Sistalgin comp.) was injected in 250 patients with severe colic pain. In 94% of the cases prompt relief from pain was observed. In addition to the reliable effect in colics of the gastrointestinal tract and the biliary duct, the high rate of success in colics of the urinary tracts should be mentioned. Good therapeutic results were also observed in pancreatitis. Only isolated cases of slight undesirable anticholinergic concomitant effects were noted. There was no effect on blood pressure and pulse rate.
mesh_terms: D000293:Adolescent; D000328:Adult; D000632:Aminopyrine / Q000031:analogs & derivatives*; D001559:Benzhydryl Compounds / Q000627:therapeutic use; D001660:Biliary Tract Diseases / Q000188:drug therapy; D001794:Blood Pressure / Q000187:drug effects; D003085:Colic / Q000188:drug therapy*; D003514:Cyclohexylamines / Q000627:therapeutic use*; D004177:Dipyrone / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D005767:Gastrointestinal Diseases / Q000188:drug therapy; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy; D014570:Urologic Diseases / Q000188:drug therapy
chemical_list: D001559:Benzhydryl Compounds; D003514:Cyclohexylamines; D004338:Drug Combinations; D000632:Aminopyrine; D004177:Dipyrone
vernacular_title: Wirkung der Kombination Pramiverin/Metamizol bei kolikartigen Schmerzzuständen