Dopamine correlates of neurological and psychological status in untreated Parkinsonism.
Thirty-seven untreated Parkinsonism patients showed significant positive correlations among decreased excretion of free dopamine, MMPI scores indicative of schizophrenic-like looseness of thinking, and the severity of all Parkinsonism signs except tremor. The data could indicate that abnormalities of dopamine metabolism may underlie both the motor and mental abnormalities of Parkinsonism.
D015102:3,4-Dihydroxyphenylacetic Acid / Q000652:urine; D000328:Adult; D000339:Affect; D000368:Aged; D004298:Dopamine / Q000378:metabolism*; D005260:Female; D006719:Homovanillic Acid / Q000652:urine; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008950:MMPI; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy / Q000378:metabolism*; D011599:Psychopathology
D015102:3,4-Dihydroxyphenylacetic Acid; D007980:Levodopa; D004298:Dopamine; D006719:Homovanillic Acid