A significant interaction between metronidazole and warfarin.
Interaction between metronidazole (Flagyl) and warfarin had been suggested based on the disulfiram-like effect of metronidazole and the known interaction of warfarin and disulfiram. This case report confirms that this interaction is clinically significant in man.
D000328:Adult; D004347:Drug Interactions; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced; D006801:Humans; D008795:Metronidazole / Q000009:adverse effects* / Q000378:metabolism; D014859:Warfarin / Q000009:adverse effects* / Q000378:metabolism
D008795:Metronidazole; D014859:Warfarin