title: Semisynthetic beta-lactam antibiotics. 8 Structure-activity relationships of alpha-sulfocephalosporins.
abstract: Synthesis and in vitro activity of a number of cephalosporins having alpha-sulfoacyl- or other acyl groups, e.g., alpha-carboxyacyl- and alpha-sulfoaminoacyl- at the 7-position and bearing a variety of heterocyclic thioether or pyridinium moieties at the 3-position are described.
mesh_terms: D001419:Bacteria / Q000187:drug effects; D002511:Cephalosporins / Q000032:analysis / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D002511:Cephalosporins