Pretectal syndrome with metastatic malignant melanoma to the posterior commissure.
A 46-year-old man with a known metastatic tumor developed the sudden onset of upgaze paralysis, impaired convergence, eyelid retraction, pupillary light-near dissociation, convergence-retraction nystagmus, and ocular skew deviation in association with subarachnoid hemorrhage. Selective interruption of the posterior commissure by metastatic melanoma provided  a precise anatomic correlation of the pretectal syndrome in man.
D001344:Autopsy; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000150:complications* / Q000473:pathology*; D008636:Mesencephalon; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009759:Nystagmus, Pathologic / Q000209:etiology*; D013345:Subarachnoid Hemorrhage / Q000209:etiology; D013577:Syndrome