Increased in vitro phosphorylation of rat liver nucleolar proteins following triiodothyronine administration.
It has been shown that triiodothyronine (Ta) administration to thyroidectomized rats induces an increase in the in vitro net 32P uptake into liver nucleolar proteins. Such an increase depends on a stimulation of the nucleolus-associated protein kinase activity and not on a lower dephosphorylation rate.
D000818:Animals; D002466:Cell Nucleolus / Q000187:drug effects / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010750:Phosphoproteins / Q000096:biosynthesis*; D051381:Rats; D013961:Thyroid Gland / Q000502:physiology; D014284:Triiodothyronine / Q000494:pharmacology*
D010750:Phosphoproteins; D014284:Triiodothyronine