[Chronic encephalomyelitis in white rats and guinea pigs].
During a 2-year observation of white rats and guinea pigs infected with human acute encephalomyelitis virus a typical picture of the disease was observed with exacerbations and remissions quite characteristic of chronic forms of multiple encephalomyelitis and multiple sclerosis of man. The presence of the virus in animals and marked pathomorphological lesions in the central nervous system were shown not to prevent remissions. The evidence of association of chronic infection with long-term viremia is also important.
D000818:Animals; D001769:Blood / Q000382:microbiology; D001921:Brain / Q000473:pathology; D002908:Chronic Disease; D004195:Disease Models, Animal; D004668:Encephalitis Viruses / Q000302:isolation & purification; D004679:Encephalomyelitis / Q000382:microbiology / Q000473:pathology; D006168:Guinea Pigs; D051381:Rats; D012075:Remission, Spontaneous
Khronicheskiĭ éntsefalomielit u belykh krys i morskikh svinok