[Effect of restoration of light flashes on energy processes in the cerebral visual system of animals developing under conditions of light deprivation].
The changes in the rate and the character of energy processes in the mitochondria of the visual system of the brain caused by prolonged dark-rearing of the animals (for 2 1/2 months from the time of birth) proved to be reversible. The extent of normalization differed in the case of mitochondria of the optic cortex and the superior colliculus. After the animals were placed under normal light conditions the rate of the mentioned processes (when glutamic acid was used as a substrate) increased in the course of a two-week restorative period, and reached the control level or even exceeded it. The rate of the electron transport in the area of cytochrome c -- cytochromoxidase succinic toxidase oxidation chain decreased at the period of restoration and approached the control level. The role of specific impulsation in the age formation of the energy processes of the brain mitochondria is discussed.
D000818:Animals; D004140:Dinitrophenols / Q000494:pharmacology; D005971:Glutamates / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption; D010655:Phenylenediamines / Q000494:pharmacology; D011817:Rabbits; D012402:Rotenone / Q000494:pharmacology; D012683:Sensory Deprivation; D013386:Succinates / Q000378:metabolism; D013477:Superior Colliculi / Q000378:metabolism / Q000648:ultrastructure; D014785:Vision, Ocular; D014793:Visual Cortex / Q000378:metabolism / Q000648:ultrastructure; D014795:Visual Pathways / Q000648:ultrastructure*
D004140:Dinitrophenols; D005971:Glutamates; D010655:Phenylenediamines; D013386:Succinates; D012402:Rotenone
Vliianie vosstanovleniia svetovoĭ impul'satsii na énergeticheskie protesessy zritel'noĭ sistemy mozga zhivotnykh, razvivaiushchikhsia v usloviiakh svetovoí deprivatsii