[Production of biologically active compounds by S, R and M forms of Mycobacterium lacticolum on a medium with n-hexadecane].
The rate of growth and production of exopolysaccharides, vitamin B2 and cetyl alcohol by different clones of S, R and M variants of Mycobacterium lacticolum 104 was studied on a medium containing n-hexadecane. A constant correlation was found to exist between the shape of the colony and the physiologo-biochemical characteristics of the bacterium. The cells of R variant had the highest growth rate, the cells of M variant, the lowest. The cell suspension of M form accumulated 0.1 mg of cetyl alcohol per 1 mg of protein during four hours; S and R forms accumulated 1.5 times less of this substance during the same time. The highest amount of flavins (2.4 mg/litre) was synthesized by the clones of S variant, the lowest amount of flavins was produced by the clones of M form. The cells of M form synthesized 4 g/litre of polysaccharides, the cells of S and R forms produced by 70 and 170% less, respectively.
D000473:Alkanes / Q000378:metabolism*; D003470:Culture Media; D005233:Fatty Alcohols / Q000096:biosynthesis*; D005415:Flavins / Q000096:biosynthesis; D014644:Genetic Variation; D009161:Mycobacterium / Q000254:growth & development / Q000378:metabolism*; D011135:Polysaccharides, Bacterial / Q000096:biosynthesis*; D012256:Riboflavin / Q000096:biosynthesis*
D000473:Alkanes; D003470:Culture Media; D005233:Fatty Alcohols; D005415:Flavins; D011135:Polysaccharides, Bacterial; D012256:Riboflavin
Obrazovanie biologicheski aktivnykh soedineniia S-, R- i M-formami Mycobacterium lacticolum na srede s n-geksadekanom