title: A system for the determination of mineralocorticoid activity by electrical potential difference measurements.
abstract: An electronic measuring instrument, which automatically calculates the rectal potential difference, has been developed to determine mineralocorticoid activity in patients with primaroid disorders. A special probe with a disposable tip enables measurements to be made on successive patients without prior cleaning of the probe. The technique, results and their clinical implications are discussed. A highly significant correlation between plasma aldosterone and rectal potential difference is demonstrated.
mesh_terms: D000450:Aldosterone / Q000097:blood; D001003:Anal Canal / Q000502:physiology; D004594:Electrophysiology / Q000295:instrumentation; D006929:Hyperaldosteronism / Q000503:physiopathology; D008564:Membrane Potentials; D008901:Mineralocorticoids / Q000502:physiology*; D012007:Rectum / Q000502:physiology; D012083:Renin / Q000097:blood; D012879:Skin Physiological Phenomena
chemical_list: D008901:Mineralocorticoids; D000450:Aldosterone; D012083:Renin