The effects of tumour extract on macrophage proliferation in lymph-nodes.
Injection of a soluble tumour extract induces mitosis in sinus macrophages of the draining lymph-node. This is not abolished by irradiation; the stimulus also induces monocytosis somewhat later. These findings make it likely that the stimulus induces mitosis in the resident lymph-node macrophage population.
D000818:Animals; D007958:Leukocyte Count; D008198:Lymph Nodes / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D008297:Male; D008938:Mitosis; D009000:Monocytes / Q000502:physiology; D009374:Neoplasms, Experimental / Q000276:immunology*; D011830:Radiation Effects; D051381:Rats; D013997:Time Factors