Prediction of radiosensitivity of individual mice by multidimensional analysis.
Ten physiological indices on each mouse were measured before an exposure to ionizing radiation. The exposure of mice to 700R of X-rays induced 45% mortality within 30 days. A prediction of death or life of each mouse was done by a multidimensional quantification. The highest success rate of prediction was obtained by using all ten indices and it resulted in 74.1%. Accordingly, it was possible to predict death of individual mice exposed to a dose around LD50 (30) with a high rate of success. When one selected five indices out of the ten indices by some criterion, the success rate of prediction decreased to 67.1%.
D000818:Animals; D001835:Body Weight; D004326:Drinking; D005260:Female; D008433:Mathematics; D051379:Mice; D011836:Radiation Tolerance