Influence of melatonin, constant light, or blinding on reproductive system of gerbils (Meriones unguiculatus).
Male and female gerbils were implanted s.c. with a pellet containing 2 mg melatonin/23 mg beeswax every 2 weeks for a total of 3 implants. A significant depression of ovarian and uterine weight was noted in female gerbils receiving melatonin implants. In the melatonin-treated male gerbils, growth of the accessory organs was significantly inhibited although testis size was not depressed.
D000818:Animals; D001766:Blindness / Q000150:complications; D001835:Body Weight / Q000187:drug effects; D005260:Female; D005835:Genitalia / Q000033:anatomy & histology*; D005849:Gerbillinae; D008027:Light; D008098:Litter Size / Q000187:drug effects; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D009929:Organ Size / Q000187:drug effects; D010053:Ovary / Q000033:anatomy & histology; D010870:Pineal Gland / Q000502:physiology; D011247:Pregnancy; D012640:Seizures / Q000209:etiology; D012669:Seminal Vesicles / Q000033:anatomy & histology; D013737:Testis / Q000033:anatomy & histology; D013950:Thymus Gland / Q000033:anatomy & histology; D014599:Uterus / Q000033:anatomy & histology
D008550:Melatonin