Influence of bradykinin and drugs blocking alpha and beta-adrenergic receptor on the stimulating effect of nialamide and L--DOPA.
It has been found that kinins increase psychostimulatory effects of Nialamide and L-DOPA as well as psychoinhibitory effects of propranolol without any changes in phentolamine action. Phentolamine and propranolol decrease stimulatory effects of Nialamide and L-DOPA only when they are given jointly with bradykinin.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001920:Bradykinin / Q000494:pharmacology*; D007980:Levodopa / Q000037:antagonists & inhibitors*; D008297:Male; D009526:Nialamide / Q000037:antagonists & inhibitors*; D010646:Phentolamine / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology*; D051381:Rats; D013268:Stimulation, Chemical
D007980:Levodopa; D011433:Propranolol; D001920:Bradykinin; D009526:Nialamide; D010646:Phentolamine