Quantitative and qualitative study of acrocentric associations in 109 normal subjects.
This study involving 109 normal subjects shows that the mean number of associations by cell seems to represent a biological constant which is not sex related and increases with age, especially after 33 years. From a qualitative point of view, the associations are not at random and their distribution varies from one individual to another. The tendency to associate is a characteristic of a given chromosome in a given individual.
D000328:Adult; D000375:Aging; D002648:Child; D002869:Chromosome Aberrations; D002875:Chromosomes; D002900:Chromosomes, Human, 1-3; D002901:Chromosomes, Human, 13-15; D002904:Chromosomes, Human, 21-22 and Y; D002905:Chromosomes, Human, 4-5; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008938:Mitosis