title: Effects of human chorionic gonadotropin preparations on amino acid uptake and incorporation into protein in vitro.
abstract: Human chorionic gonadotropin preparations were tested for their effect on protein metabolism by cultured fibroblasts. Commercial preparations of HCG strongly inhibit amino acid uptake and incorporation into protein by a variety of human adult and fetal fibroblast lines, whereas, highly purified HCG is without such an effect.
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D001692:Biological Transport; D002478:Cells, Cultured; D006063:Chorionic Gonadotropin / Q000494:pharmacology*; D005333:Fetus; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D008168:Lung / Q000187:drug effects / Q000378:metabolism; D014176:Protein Biosynthesis / Q000187:drug effects*; D012867:Skin / Q000187:drug effects / Q000378:metabolism
chemical_list: D000596:Amino Acids; D006063:Chorionic Gonadotropin