[Characteristics of several indices of the mitotic regime of clone strains of HeLa cells infected with adenovirus type 7].
The effect of adenovirus type 7 on the mitotic activity, the level and qualitative characteristics of pathological mitoses was studied in mycoplasma-free and latently mycoplasma-infected cells of clone HeLa cell lines with different sensitivity to this virus. The level and the extent of changes of the mitotic regimen in adenovirus-infected cells depend upon their susceptibility to the virus and initial characteristics of the mitotic regimen of the culture which is somehow related to the presence or absence of mycoplasmal contaminants in the culture. Successful analysis of the virus effect on the mitotic regimen of one or another cell system requires the use of a culture with minimal pathology of the mitotic apparatus and careful tests for the lack of mycoplasmal contaminants.
D000256:Adenoviridae; D002999:Clone Cells; D005260:Female; D006367:HeLa Cells; D006801:Humans; D008938:Mitosis; D009174:Mycoplasma
Kharakteristika nekotorykh pokazateleĭ mitoticheskogo rezhima klonovykh liniĭ kletok HeLa, zarazhennykh adenovirusom tipa 7