Degranulating activity in hybrid cells derived from rat peritoneal mast cells and ehrlich ascites.
Fusion of rat mast cells and Ehrlich ascites tumor cells was mediated by HVJ. Compound 48/80-induced degranulation occurred in the fused cells formed from two mast cells and one tumor cell, but not in the fused cells from one mast cell and two or more tumor cells.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor; D003594:Cytoplasmic Granules / Q000187:drug effects; D006822:Hybrid Cells / Q000187:drug effects*; D008407:Mast Cells; D051381:Rats; D003189:p-Methoxy-N-methylphenethylamine / Q000494:pharmacology*
D003189:p-Methoxy-N-methylphenethylamine