[Psychotropic drugs and glaucoma (author's transl)].
The i.o. pressure and tonography were studied on 51 patients with endogenous depressions. The patients were treated 10-43 days with psycho-pharmacological drugs (Indoline, Imipramine, Amitriptyline, Noxiptiline and Phenothiazine). In no case does the therapy with the drugs induce an increase of i.o. pressure or-in normal eyes-of tonography. In latent of manifest glaucoma (7 patients) Clomipramine increased the tonography in 1 case, whereas Amitriptyline and Noxiptiline reduced it in 4 cases. The study demonstrated that the commonly used psycho-pharmaca are no contraindication to wide-angle glaucoma.
D000328:Adult; D000368:Aged; D002997:Clomipramine / Q000009:adverse effects; D003863:Depression / Q000188:drug therapy; D003891:Desipramine / Q000009:adverse effects; D003986:Dibenzocycloheptenes / Q000009:adverse effects; D005260:Female; D005476:Fluphenazine / Q000009:adverse effects; D005901:Glaucoma / Q000139:chemically induced; D006801:Humans; D007099:Imipramine / Q000009:adverse effects; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009888:Opipramol / Q000009:adverse effects; D010464:Perazine / Q000009:adverse effects; D011619:Psychotropic Drugs / Q000009:adverse effects* / Q000627:therapeutic use; D013888:Thiothixene / Q000009:adverse effects; D014065:Tonometry, Ocular
D003986:Dibenzocycloheptenes; D011619:Psychotropic Drugs; D013888:Thiothixene; D010464:Perazine; D009888:Opipramol; D002997:Clomipramine; D007099:Imipramine; D005476:Fluphenazine; D003891:Desipramine
Psychopharmaka und Glaukom