title: [Studies on the excretion of various aminoglycosides in rat milk (author's transl)].
abstract: 10 mg/kg of strepto-, neo-, kanamycin, genta- and sisomicin were applied s.c. to rats in lactation. After 0.5, 1, 2, 4, 6, 8 and 24 h the animals were milked. The antibacterial concentrations in the milk were determined in comparison to the serum concentrations. Strepto-, neo- and kanamycin showed the highest concentrations in the serum, genta- and sisomicin the highest in the milk.
mesh_terms: D000617:Aminoglycosides / Q000378:metabolism*; D000818:Animals; D005260:Female; D005839:Gentamicins / Q000097:blood / Q000378:metabolism; D007612:Kanamycin / Q000097:blood / Q000378:metabolism; D007700:Kinetics; D007774:Lactation; D008892:Milk / Q000378:metabolism*; D009355:Neomycin / Q000097:blood / Q000378:metabolism; D011247:Pregnancy; D051381:Rats; D012853:Sisomicin / Q000097:blood / Q000378:metabolism; D013307:Streptomycin / Q000097:blood / Q000378:metabolism
chemical_list: D000617:Aminoglycosides; D005839:Gentamicins; D007612:Kanamycin; D009355:Neomycin; D012853:Sisomicin; D013307:Streptomycin
vernacular_title: Untersuchungen zur Ausscheidung verschiedener Aminoglykoside in der Rattermilch