Endothelialization of filtering bleb in iris nevus syndrome.
Late failure of a filtering cicatrix occurred in a patient who had had surgery to control the glaucoma associated with the iris nevus syndrome (Cogan-Reese). The internal surface of the filtration site, as well as the anterior chamber angle, proved to be lined by corneal endothelium that had laid down a new, thick basement membrane (Descemet). The new endothelium-basement membrane probably obstructed the flow of aqueous into the bleb. Endothelialization of a filtering bleb is not unique to the iris nevus syndrome; other causes are discussed.
D003316:Corneal Diseases / Q000150:complications; D003886:Descemet Membrane / Q000473:pathology; D004727:Endothelium; D005134:Eye Neoplasms / Q000473:pathology / Q000601:surgery*; D005901:Glaucoma / Q000150:complications / Q000601:surgery*; D006801:Humans; D006988:Hyphema / Q000150:complications; D007498:Iris / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009506:Nevus / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications; D013577:Syndrome; D014603:Uveal Diseases / Q000209:etiology