Fuzzy, a hypotrichotic mutant in linkage group I of the Norway rat.
A new recessive hypotrichosis gene in the rat designated fuzzy (fz) is described. Fuzzy is linked to albino (c) in linkage group I with a 18.13 +/- 3.05 percent recombination. After an initial sparse hair coat, the fuzzy animals rapidly become devoid of hair. Histologically the skin of these animals has poorly developed, and often cystic hair follicles that contain accumulations of keratinacious material.
D000505:Alopecia / Q000235:genetics*; D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D005808:Genes, Recessive; D008040:Genetic Linkage; D007039:Hypotrichosis / Q000235:genetics*; D008297:Male; D009154:Mutation; D010641:Phenotype; D051381:Rats; D012737:Sex Factors; D012867:Skin / Q000473:pathology