[Electric conductivity of lipid membranes in the presence of proteolytic enzymes and their substrates].
It is shown that there are spasmodic changes of electroconductivity in bimolecular membranes in the presence of alpha-chimotripsin and denatured ovalbumin or glycyl-d,L-beta-phenylalanine. These conductivity changes are not due to the interaction ob proteolysis products with lipid bilayer but result from the interaction of alpha-chimo trypsin with the substrate or competing inhibitor. Probability of the state with a specific conductivity depends on the membrane voltage. A modified membrane has a low ionic selectivity.
D002784:Cholesterol; D002918:Chymotrypsin; D004553:Electric Conductivity; D008567:Membranes, Artificial; D010047:Ovalbumin; D010447:Peptide Hydrolases; D010649:Phenylalanine; D010743:Phospholipids; D011489:Protein Denaturation
D008567:Membranes, Artificial; D010743:Phospholipids; D010649:Phenylalanine; D010047:Ovalbumin; D002784:Cholesterol; D010447:Peptide Hydrolases; D002918:Chymotrypsin
Elektroprovodnost' lipidnykh membran v prisutstvii proteoliticheskikh fermentov i ikh substratov