Immunoreactive insulin (IRI) dynamics in GH-deficient patients following intravenous glycine loading.
In hypopituitary short-statured patients glycine intravenous injection (250 mg/kg of body weight) provokes a mild and inconstant stimulation of IRI release followed by a significant fall down. Though insiginificant (P 0.064), the prevalence of IRI responsive individuals to glycine in the patients group of idiopathic etiology could be of pathophysiological importance.
D000293:Adolescent; D000328:Adult; D002648:Child; D005998:Glycine / Q000494:pharmacology*; D013006:Growth Hormone / Q000172:deficiency*; D006801:Humans; D007018:Hypopituitarism / Q000378:metabolism; D007118:Immunoassay; D007328:Insulin / Q000276:immunology / Q000378:metabolism*; D000078790:Insulin Secretion; D008297:Male
D007328:Insulin; D013006:Growth Hormone; D005998:Glycine