[Effect of supernatant from PHA-stimulated lymphocyte culture on blastic transformation of peripheral blood lymphocytes in healthy controls and patients with chronic lymphatic leukemia].
It was found that supernatant from a PHA-stimulated 3-day-old culture of peripheral blood lymphocytes of healthy people had the ability of stimulating blastic transformation of peripheral blood lymphocytes of other healthy people. The same amount of supernatant caused a much lower blastic transformation of peripheral blood lymphocytes from patients with chronic lymphatic leukaemia. The tested supernatant caused no increase in the degree of blastic transformation of PHA-stimulated lymphocytes from patients with chronic lymphatic leukaemia.
D002478:Cells, Cultured; D006801:Humans; D037102:Lectins / Q000494:pharmacology; D007945:Leukemia, Lymphoid / Q000276:immunology*; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*
D037102:Lectins
Wpływ supernatantu ze stymulowanej PHA hodowli limfocytów na transformacje blastyczna limfocytów krwi obwodowej ludzi zdrowych i chorych na przewlekła białaczke limfatyczna