Effects of superovulation on fetal development and hormone levels in the pregnant hamster.
Treatment of hamsters with 30 i.u. PMSG induced ovulation of 46 ova/animal, 90% of which were fertilized. CL growth was normal. About 27 zygotes/animal implanted and at term (Day 16) the litter size of the PMSG-treated hamsters was 21 compared to the normal number of 10. Parturition occurred at the normal time. Average weight at birth was about 500 mg less for young of PMSG-treated mothers than for controls. Differences were found in the serum progesterone and oestradiol concentrations of the treated and control hamsters, but serum FSH and LH levels were similar.
D000818:Animals; D001724:Birth Weight / Q000187:drug effects; D003338:Corpus Luteum / Q000033:anatomy & histology; D006224:Cricetinae; D004958:Estradiol / Q000097:blood; D005260:Female; D005333:Fetus / Q000187:drug effects*; D005640:Follicle Stimulating Hormone / Q000097:blood; D006064:Gonadotropins, Equine / Q000494:pharmacology*; D007986:Luteinizing Hormone / Q000097:blood; D008647:Mesocricetus; D009929:Organ Size / Q000187:drug effects; D010053:Ovary / Q000033:anatomy & histology; D010060:Ovulation; D011374:Progesterone / Q000097:blood; D013480:Superovulation
D006064:Gonadotropins, Equine; D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone