[Homologous articular cartilage transplantation in animal experiments. Preliminary studies on sheep (author's transl)].
Homologous articular cartilage without subchondral bone instead of the usual osteochondral grafts was transplanted in sheep. The transplants were fixed to the host by a biological tissue adhesive based on fibrinogen clotting. Light- and electronmicroscopic studies showed viable transplants up to 7 months and a stable bony union with the host through endochondral bone formation. A additional external fixation of the joint after transplantation or the use of a conventional cyanoacrylate tissue adhesive failed to achieve positive results. The relations of these preliminary findings for restorative techniques of articular cartilage defects are discussed.
D000818:Animals; D002358:Cartilage, Articular / Q000473:pathology / Q000637:transplantation*; D003487:Cyanoacrylates; D005260:Female; D005337:Fibrin; D008297:Male; D008854:Microscopy, Electron; D012756:Sheep; D013997:Time Factors; D014014:Tissue Adhesives; D014184:Transplantation, Homologous / Q000379:methods
D003487:Cyanoacrylates; D014014:Tissue Adhesives; D005337:Fibrin
Die homologe reine Gelenkknorpeltransplantation im Tierexperiment. Vorläufige experimentelle Studien am Schaf