Absence of an effect of t-alleles on epididymal and testicular metabolism of 5-3H-uridine in mice.
Earlier reports have suggested that the epididymis secretes RNA, and that the amount of these secretions varies among T/t6, T/t12 and C57BR mice. In this report, the epididymal perfusate, the total uptake and incorporation of 5-3H-uridine into the epididymis and testicle were examined. Mice examined were T/t6 and +/+ (B6D2F1) and their F1 hybrids, and T/t12 and +/+ (Swiss Webster) and their F1 hybrids. No t-related or age-related effect was seen. However, the F1 hybrids of T/t6 and +/+ (B6D2F1) were significantly lower than the parents at the 4-hour interval.
D000367:Age Factors; D000483:Alleles; D000818:Animals; D003433:Crosses, Genetic; D004822:Epididymis / Q000378:metabolism*; D005838:Genotype; D006579:Heterozygote; D008297:Male; D051379:Mice / Q000378:metabolism*; D013737:Testis / Q000378:metabolism*; D014529:Uridine / Q000378:metabolism*
D014529:Uridine