[Lysosomal enzymes in the neoplastic pathology of the uterine cervix. Study of acid phosphatase in the diagnostic test of vaginal secretions in patients with pre-invasive and invasive cancer of the uterine cervix. I. Methods and preliminary experiences].
Gomori's method was used in the detection of positive -- or negative -- phosphatase granulations and their intracellular locations in vaginal secretions from 10 normal women and 20 patients with cervical neoplasia in various stages. Positive-phosphatase granulations were absent in normal subjecta and those with advanced neoplasia, whereas mainly large and medium-sized paranuclear positive granulations were a prominent feature of epithelial cells from patients from state 0-ToNoMo carcinomas. Further details will be given in a second note.
D000135:Acid Phosphatase / Q000378:metabolism*; D004796:Clinical Enzyme Tests; D004847:Epithelial Cells; D005260:Female; D006801:Humans; D008247:Lysosomes / Q000201:enzymology*; D002583:Uterine Cervical Neoplasms / Q000201:enzymology* / Q000473:pathology; D014626:Vaginal Smears
D000135:Acid Phosphatase
Gli enzimi lisosomiali nella patologia neoplastica del collo dell'utero Studio della fosfatasi acida quale test diagnostico nei secreti vaginali di pazienti portatrici di ca. preinvasivi e invasivi del collo dell'utero. Nota I - Metodiche ed esperienze preliminari