[Research on the state of the cell membrane and the mechanism of corneal autolysis in the conservation process (author's transl)].
In this work we have thrown light on the basis of our experiments on 530 rabbits', dogs' and human eyes preserved under various conditions on the influence of antioxidation substances on corneal preservation. The development of autolysis is highly dependent on the absence of antioxident - also important for the survival of the cornea. From our results we have drawn conclusions regarding the participation of antioxidant (-tocopherol, chondroitin sulphate) on the self-regulating oxidation of structural lipids in the cell membranes of the cornea, and its effects on preservation.
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001329:Autolysis; D002462:Cell Membrane / Q000502:physiology; D002463:Cell Membrane Permeability / Q000187:drug effects; D003315:Cornea / Q000187:drug effects* / Q000502:physiology; D004285:Dogs; D006801:Humans; D050356:Lipid Metabolism; D010084:Oxidation-Reduction / Q000187:drug effects; D011817:Rabbits; D014021:Tissue Preservation
D000975:Antioxidants
Erforschung des Zustandes der Zellmembran und der Mechanismen der Hornhautautolyse bei der Konservierung. II. Rolle der Antioxydationsmittel in der selbstregelnden Oxydation struktureller Lipoide von Zellmembranen der Hornhaut bei ihrer Konservierung