title: Pharmacological studies on root bark of mulberry tree (Morus alba L.)
abstract: Pharmacological studies were done on the root bark of mulberry tree and pharmacological effects were compared with the clinical effects of "Sohakuhi" in Chinese medicine. n-Butanol- and water-soluble fractions of mulberry root had similar effects except for those on the cadiovascular system. Both fractions showed cathartic, analgesic, diuretic, antitussive, antiedema, sedative, anticonvulsant, and hypotensive actions in mice, rats, guinea pigs and dogs. There appears to be a correlation between the experimental pharmacological results and the clinical applications of mulberry root found in the literature on Chinese medicine.
mesh_terms: D000700:Analgesics; D000779:Anesthetics, Local; D000818:Animals; D000893:Anti-Inflammatory Agents; D000927:Anticonvulsants; D000996:Antitussive Agents; D001522:Behavior, Animal / Q000187:drug effects; D001831:Body Temperature / Q000187:drug effects; D002400:Cathartics; D003315:Cornea / Q000187:drug effects; D004232:Diuretics; D004285:Dogs; D005769:Gastrointestinal Motility / Q000187:drug effects; D006168:Guinea Pigs; D006439:Hemodynamics / Q000187:drug effects; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology* / Q000633:toxicity; D051381:Rats; D014197:Trees
chemical_list: D000700:Analgesics; D000779:Anesthetics, Local; D000893:Anti-Inflammatory Agents; D000927:Anticonvulsants; D000996:Antitussive Agents; D002400:Cathartics; D004232:Diuretics; D010936:Plant Extracts