title: The influence of a diet rich in wheat fibre on the human faecal flora.
abstract: The effect on the faecal flora of adding wheat fibre to a controlled diet in four healthy volunteers for a 3-week period has been observed. No change in the concentration of the bacteria in the bacterial groups counted was found, although there was a slight increase in total output associated with increased faecal weight. The predominant organisms in all subjects were non-sporing anaerobes, but the dominant species in each subject was different and was unaffected by changing the diet. Similarly, the concentration of faecal beta-glucuronidase detected in two subjects was unaltered and the concentration of clostridia able to dehydrogenate the steroid nucleus found in one subject was unaltered. It is suggested that the faecal microflora is not primarily controlled by the presence of undigested food residues in the large bowel.
mesh_terms: D000328:Adult; D001419:Bacteria / Q000302:isolation & purification; D001439:Bacteroides / Q000302:isolation & purification; D002482:Cellulose; D003013:Clostridium / Q000302:isolation & purification; D004043:Dietary Fiber; D004755:Enterobacteriaceae / Q000302:isolation & purification; D005051:Eubacterium / Q000302:isolation & purification; D005243:Feces / Q000201:enzymology / Q000382:microbiology*; D005966:Glucuronidase / Q000378:metabolism; D006801:Humans; D007778:Lactobacillus / Q000302:isolation & purification; D008297:Male; D010460:Peptococcus / Q000302:isolation & purification; D013045:Species Specificity; D013291:Streptococcus / Q000302:isolation & purification; D014908:Triticum
chemical_list: D004043:Dietary Fiber; D002482:Cellulose; D005966:Glucuronidase