title: [Recurrent polyneuropathy with a 19-year course, associated with a benign IgG monoclonal gammapathy].
abstract: A case of recurrent polyradiculoneuritis in a 54-year-old man is described. It is exceptional because of its lengthy development over a period of 19 years and by its association with a paraprotein of the IgE type without anyother anomal. Corticotherapy had a favourable effect on the clinical symptoms but did not affect the amount of monoclonal immunoglobulin in the serum. The nosological position of this neuropathy and the type of gammapathy are discussed. An immune mechanism seems likely, but no proof of a link between the neuropathy and the gammapathy could be found.
mesh_terms: D001853:Bone Marrow / Q000276:immunology; D001854:Bone Marrow Cells; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011128:Polyradiculopathy / Q000188:drug therapy / Q000276:immunology*; D011241:Prednisone / Q000627:therapeutic use*; D012008:Recurrence
chemical_list: D002556:Cerebrospinal Fluid Proteins; D011241:Prednisone
vernacular_title: Pol-neuropathie a rechutes, évoluant depuis 19 ans, associée à une gammapathie monoclonale IgG bénigne. Effet favorable de la corticothérapie