Pharmacokinetic interpretation of cephradine levels in serum after intravenous and extravascular administration in humans.
Pharmacokinetic parameters were calculated from intravenous data based upon a two-compartment open model. These parameters were subsequently used to determine the absorption rates and bioavailability of cephradine administered intramuscularly and orally. The results indicate that cephradine obeys dose-independent kinetics and that biological availability is complete from all dosage forms.
D000284:Administration, Oral; D000328:Adult; D001682:Biological Availability; D002511:Cephalosporins / Q000097:blood*; D002515:Cephradine / Q000008:administration & dosage / Q000097:blood*; D006801:Humans; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D007700:Kinetics; D008297:Male
D002511:Cephalosporins; D002515:Cephradine