[Cell division, cytolysis and regeneration after cyclophosphamide].
Cytokinetic effects of 5 or 20 mg cyclophosphamide/kg body weight on thoracic duct lymph and blood cells of calves were analyzed. The larger dose caused a temporary cessation of lymphoid cell division, reduced the output of nondividing small lymphoid cells and impaired proliferation of neutrophil precursors. Feedback mechanisms acting on GO/G1 cells controlled the proliferation of lymphoid cells.
D000818:Animals; D002417:Cattle; D002455:Cell Division / Q000187:drug effects; D003520:Cyclophosphamide / Q000494:pharmacology*; D008196:Lymph / Q000166:cytology; D008214:Lymphocytes / Q000187:drug effects; D009504:Neutrophils / Q000187:drug effects; D013897:Thoracic Duct
D003520:Cyclophosphamide
Zellteilung, Zytolyse und Regeneration nach Cyclophosphamid