[Effect of the temperature regimen on the kinetic and thermodynamic functions of the enzyme urease in the helminths of warm-blooded and cold-blooded animals].
The determination of the constant of the urea fission rate and study of the temperature dependence (activation energy) of the urease activity on warm- and cold-blooded animals in Ascaris suum and Contracaecum aduncum were undertaken. It has been shown that the constant of the urea fission rate in C. aduncum is more than an order of magnitude higher than that in A. suum. At a temperature of 17 degrees the rate of this process in C. aduncum changes but little while in A. suum it practically ceases. On the contrary, at 47 degrees the urease ferment activity in A. suum increases considerably while in C. aduncum the process rate does not rise as compared to that at 37 degrees. The subsequent calculations of the energy activation have shown that a certain adaptation to definite conditions of ferments functioning can take place.
D000818:Animals; D001200:Ascaris / Q000201:enzymology; D004734:Energy Metabolism; D004789:Enzyme Activation; D005399:Fishes / Q000469:parasitology; D006168:Guinea Pigs; D006376:Helminths / Q000201:enzymology*; D007700:Kinetics; D008657:Metabolic Clearance Rate; D013045:Species Specificity; D013552:Swine / Q000469:parasitology; D013696:Temperature; D013816:Thermodynamics; D014508:Urea / Q000378:metabolism; D014510:Urease / Q000378:metabolism*
D014508:Urea; D014510:Urease
Vliianie temperaturnogo rezhima na kineticheskie i termodinamicheskie funktsii fermenta ureazy y gel'mintov teplokrovnykh i kholodnokrovnykhzhivotnykh