title: The influence of some antidepressant drugs on cardiac function. IV. Influence of blood supply of the heart in situ.
abstract: In in situ experiments with cats, impiramine, nortriptyline and amitriptyline depressed arterial blood pressure, diminished coroncary flow and amplitude of the heart's contraction, and slowed cardiac action.
mesh_terms: D000639:Amitriptyline / Q000494:pharmacology*; D000818:Animals; D002415:Cats; D003326:Coronary Circulation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006321:Heart / Q000187:drug effects*; D006339:Heart Rate; D007099:Imipramine / Q000494:pharmacology*; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects; D009661:Nortriptyline / Q000494:pharmacology*
chemical_list: D000639:Amitriptyline; D009661:Nortriptyline; D007099:Imipramine