title: [Changes of kappa/lambda ratio of human serum immunoglobulins in the course of development].
abstract: In sera of normal individuals of different age groups the kappa- and lambda-type immunoglobulins were measured and the kappa/lambda ratio was calculated. The relative concentration of lambda-immunoglobulins in sera of newborns and young children was found to be significantly higher than in the adult sera. The well-known asynchronous maturation of immunoglobulin classes and IgG subclasses in the early childhood is evidently accompagnied by a asynchronous maturation of immunoglobulin types.
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001782:Blood Donors; D005260:Female; D006801:Humans; D007074:Immunoglobulin G; D007136:Immunoglobulins; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D008968:Molecular Conformation
chemical_list: D007074:Immunoglobulin G; D007136:Immunoglobulins
vernacular_title: Veränderungen des kappa/lambda-Verhältnisses der menschlichen Serumimmunglobuline im Verlaufe der Entwicklung