Anti-inflammatory activity of isoxicam in combination with aspirin or D-propoxyphene.
Unlike several arylacetic acid derivatives (indomethacin, fenoprofen, ibuprofen, flurbiprofen and naproxen), the anti-arthritic activity of isoxicam is not reduced in the adjuvant-induced polyarthritis assay by the concomitant administration of aspirin or D-propoxyphene.
D000818:Animals; D000893:Anti-Inflammatory Agents; D001169:Arthritis, Experimental / Q000188:drug therapy / Q000517:prevention & control; D001241:Aspirin / Q000008:administration & dosage* / Q000627:therapeutic use; D001835:Body Weight; D011431:Dextropropoxyphene / Q000008:administration & dosage* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D007555:Isoxazoles / Q000008:administration & dosage* / Q000627:therapeutic use; D008297:Male; D009929:Organ Size; D010080:Oxazoles / Q000008:administration & dosage*; D010894:Piroxicam / Q000031:analogs & derivatives; D051381:Rats; D013843:Thiazines / Q000008:administration & dosage* / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D007555:Isoxazoles; D010080:Oxazoles; D013843:Thiazines; D010894:Piroxicam; C013580:isoxicam; D001241:Aspirin; D011431:Dextropropoxyphene