[Inhibition of exogenous lactate dehydrogenase in mammalian ova].
A technique of microinjection of exogenic commercial lactate dehydrogenase into the zygotes of rats has been elaborated. A selective inhibition of exogenous LDH-3, LDH-4 and LDH-5 was registered in the ova-recipients. Attempts to reproduce the selective inhibition of LDH-3, LDH-4 and LDH-5 by a microhomogenate made of zygotes were not successful. The identification of LDH from ovocytes and exogenic LDH was made according to their electrophoretic mobility relative to Bromphenol blue and LDH-1.
D000818:Animals; D005260:Female; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D010063:Ovum / Q000201:enzymology*; D051381:Rats
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
Ob ingibirovanii ékzogennoĭ laktatdegidrogenazy v iaĭtsekletkakh mlekopitaiushchikh