The origin of urinary hydroxylysyl glycosides in Paget's disease of bone and in primary hyperparathyroidism.
The urinary excretion of glucosyl-galactosyl-hydroxylysine and of galactosyl-hydroxylysine were studied in Paget's disease of bone and in primary hyperparathyroidism. Both metabolites were increased in these diseases. Although glucosyl-galactosyl-hydroxylysine is not abundant in bone collagen, it is possible that a part of it originates from calcified tissue.
D000469:Alkaline Phosphatase / Q000097:blood; D001842:Bone and Bones / Q000378:metabolism; D002116:Calcitonin / Q000494:pharmacology; D003094:Collagen / Q000378:metabolism; D006027:Glycosides / Q000652:urine*; D006801:Humans; D006901:Hydroxylysine / Q000652:urine*; D006961:Hyperparathyroidism / Q000652:urine*; D010001:Osteitis Deformans / Q000652:urine*
D006027:Glycosides; D006901:Hydroxylysine; D002116:Calcitonin; D003094:Collagen; D000469:Alkaline Phosphatase