[Degradation and elimination of the anthelminitic 131I-rafoxanid in cattle and sheep].
Rafoxanide, labelled by 131J, was applied orally in oily solution to cattle and sheep, 12 and 17 mg/kg bodymass, resp. The half time of 131J in blood in 12,5 and 10,5 d for sheep and cattle, resp., the compound is adsorbed to proteins in blood. In the milk a maximal level of 3-3,5 ppm (calculated as total 131J) after 4-6 d was measured. More detailed results regarding the metabolism of rafoxanide are hitherto not possible.
D000818:Animals; D002417:Cattle / Q000378:metabolism*; D005243:Feces / Q000032:analysis; D008892:Milk / Q000032:analysis; D011485:Protein Binding; D011888:Rafoxanide / Q000378:metabolism* / Q000652:urine; D012457:Salicylamides / Q000378:metabolism*; D012756:Sheep / Q000378:metabolism*
D012457:Salicylamides; D011888:Rafoxanide
Untersuchungen zum Abbau und zur Ausscheidung des Anthelminthikums 131J-Rafoxanid an Rind und Schaf