title: Nephrogenic adenoma: a form of adenomatous metaplasia of the bladder. A clinical and electron microscopical study.
abstract: 3 additional cases of "nephrogenic adenoma" of the bladder are added to the 20 previously reported cases. Light and electron microscopic studies of the first 2 cases support the hypothesis of urothelial metaplasia. The name "adenomatous metaplasia" should replace "nephrogenic adenoma". Malignant change occurred in the third case, suggesting that this ought to be regarded as a potentially dangerous from of metaplasia. In the absence of malignant change, ileocaecocystoplasty with subtotal cystectomy afforded symptomatic cure in 2 cases: radical cystectomy was performed in the third because of malignant adenocarcinoma.
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000601:surgery / Q000648:ultrastructure; D000328:Adult; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis* / Q000601:surgery / Q000648:ultrastructure; D008679:Metaplasia; D008854:Microscopy, Electron; D001743:Urinary Bladder / Q000473:pathology*; D001745:Urinary Bladder Diseases / Q000473:pathology / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000601:surgery / Q000648:ultrastructure