Combined simultaneous radiotherapy and chemotherapy for treatment of unresectable and/or metastatic cancer.
The present program was started in 1971 and is being conducted as a probing study. We believe that the only conclusion that can be drawn thus far is that, by utilizing the conventional cobalt therapy and chemotherapy together, there has been no increase in morbidity or mortality. The patients appear to have tolerated this therapy well on an out-patient basis with hospitalization only being needed occasionally. By the time the radiotherapist and/or chemotherapist sees the patient, the cancer is usually systemic. Therefore, a combined approach should be seriously considered since we have found that the patients tolerate this program well. The authors also feel that there has been an improvement, thus far, in terms of completion and duration of response. Further studies are currently being carried out in order to arrive at a more satisfactory statistical conclusion.
D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*
D000970:Antineoplastic Agents