Action of caerulein, glucagon or prostaglandin E1 on the motility of intestinal villi.
If injected into the artery supplying the first jejunal loop of dogs, caerulein increases, glucagon and PGE-1 decrease villous motility significantly. The relationship between the natural logarithm of the drug doses and their effects is linear.
D000818:Animals; D002108:Ceruletide / Q000494:pharmacology*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005769:Gastrointestinal Motility / Q000187:drug effects*; D005934:Glucagon / Q000494:pharmacology*; D008297:Male; D011458:Prostaglandins E / Q000494:pharmacology*
D011458:Prostaglandins E; D002108:Ceruletide; D005934:Glucagon