[Research on heterocyclic compounds. IV. Imidezopyrimidine acetic acids].
A group of ethyl imidazo (1,2-a) and imidazo (1,2-c)pyrimidin-2-acetates was prepared, starting respectively from 2-amino- and 4-aminopyrimidines, by reaction with ethyl 4-bromoacetoacetate. From these esters the corresponding acids were prepared and their antiinflammatory activity was evaluated.
D000085:Acetates / Q000138:chemical synthesis; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis; D007093:Imidazoles / Q000138:chemical synthesis*; D011743:Pyrimidines / Q000138:chemical synthesis*; D051381:Rats; D012106:Research
D000085:Acetates; D000893:Anti-Inflammatory Agents; D007093:Imidazoles; D011743:Pyrimidines
Ricerche su composti eterociclici. IV. Acidi imidazopirimidinacetici