title: Klinefelter's syndrome and bladder cancer.
abstract: A patient with Klinefelter's syndrome is described who also had transitional cell carcinoma of the bladder. His mother and maternal grandfather died of neoplasms. It is suggested that neoplasm and aneuploidy in the same family could have been caused by an inherited chromosomal instability rather than coincidence.
mesh_terms: D000328:Adult; D002295:Carcinoma, Transitional Cell / Q000150:complications* / Q000473:pathology; D006801:Humans; D007713:Klinefelter Syndrome / Q000150:complications*; D008297:Male; D012729:Sex Chromosome Aberrations; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000473:pathology