title: Activation by cholera toxin of adenylate cyclase solubilized from rat liver.
abstract: Cholera toxin, or peptide A1 from the toxin, activates adenylate cyclase solubilized from rat liver with Lubrol PX, provided that cell sap, NAD+, ATP and thiol-group-containing compounds are present. The activation is abolished by antisera to whole toxin, but not to subunit B.
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D001427:Bacterial Toxins / Q000494:pharmacology*; D004789:Enzyme Activation; D008099:Liver / Q000201:enzymology*; D010446:Peptide Fragments / Q000494:pharmacology; D051381:Rats; D014734:Vibrio cholerae
chemical_list: D001427:Bacterial Toxins; D010446:Peptide Fragments; D000262:Adenylyl Cyclases