[Serum and myocardial enzyme activity in experimental myocardial infarct].
In 150 canine experiments it has been established that in myocardial infarction the activity of heart muscle enzymes decreases significantly and persistently in the zone of necrosis, moderately and reversibly--beyond this zone, individual enzymes being unequally sensitive to the effects of the given injuring factor. The shifts in the activity of the serum and heart muscle enzymes correlate only in the early days following the reproduction of the pathological state, while the levelling of hyperenzymia is accompanied by an enhancement of the enzymatic disorders in the myocardium in cases of infarction.
D000410:Alanine Transaminase / Q000378:metabolism; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism; D004285:Dogs; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006019:Glycolysis; D007655:Ketoglutarate Dehydrogenase Complex / Q000378:metabolism; D009203:Myocardial Infarction / Q000097:blood / Q000201:enzymology*; D009206:Myocardium / Q000201:enzymology*; D010447:Peptide Hydrolases / Q000378:metabolism; D013385:Succinate Dehydrogenase / Q000378:metabolism; D014174:Transketolase / Q000378:metabolism
D005954:Glucosephosphate Dehydrogenase; D007655:Ketoglutarate Dehydrogenase Complex; D013385:Succinate Dehydrogenase; D014174:Transketolase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D010447:Peptide Hydrolases
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