[Effects and mechanism of a locally combined treatment with radiation and heat therapy (author's transl)].
An animal experimental study on solid Walker-tumors was undertaken to determine the therapeutic effects utilizing hyperthermy in the form of combined decimeter wave megavolt treatment. Noted was the superior effect of combination therapy as compared to exclusive use of radiation therapy. Hyperthermy therapy alone does inhibit tumor growth but not involution. This inhibiting characteristic of hyperthermy probably changes cellular mitotic rhythm in the form of cellular synchronisation. The indications for combined hyperthermy megavolt treatment is hypoxic malignant tumors of low radiation sensitivity, especially in superficial and shallow tissue regions. The above treatment is tolerated well and no serious side effects have been observed.
D000818:Animals; D002277:Carcinoma / Q000532:radiotherapy; D002279:Carcinoma 256, Walker / Q000532:radiotherapy / Q000628:therapy*; D002471:Cell Transformation, Neoplastic / Q000528:radiation effects; D002588:Cesium Radioisotopes; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D004195:Disease Models, Animal; D004583:Electrons; D005260:Female; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D006979:Hyperthermia, Induced; D008297:Male; D008325:Mammary Neoplasms, Experimental / Q000628:therapy*; D008872:Microwaves / Q000627:therapeutic use; D008875:Middle Aged; D011867:Radioisotope Teletherapy; D011879:Radiotherapy Dosage; D051381:Rats
D002588:Cesium Radioisotopes; D003037:Cobalt Radioisotopes
Leistung und Wirkungsmechanismus einer lokalen kombinierten Strahlentherapie- Wärmeanwendung