title: Diterpene acids as larval growth inhibitors.
abstract: Kaurenoic and trachylobanoic acids from sunflower inhibited larval development in several Lepidoptera species. The tricyclic resin acids were also effective in curtailing growth of Pectinophora gossypiella and either reduction to carbinol or esterification of the carboxyl group lowered activity. Partial reversal of growth inhibition in the presence of relatively large amounts of cholesterol suggests an interaction with the insects' hormonal system.
mesh_terms: D000818:Animals; D004224:Diterpenes / Q000494:pharmacology*; D006368:Helianthus; D007814:Larva / Q000187:drug effects / Q000254:growth & development; D007915:Lepidoptera / Q000187:drug effects* / Q000254:growth & development
chemical_list: D004224:Diterpenes