Sex specific differences in chlorimipramine inhibition of serotonin uptake in human platelets.
The uptake of 14C-serotonin in platelet-rich plasma was similar in clinically healthy men and women. Serotonin uptake inhibition by chlorimipramine was significantly less in women than in men, the extent of inhibition correlating with the stage of the menstrual cycle.
D001792:Blood Platelets / Q000187:drug effects*; D002997:Clomipramine / Q000494:pharmacology*; D003984:Dibenzazepines / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D008598:Menstruation; D012701:Serotonin / Q000097:blood*; D012737:Sex Factors
D003984:Dibenzazepines; D012701:Serotonin; D002997:Clomipramine