Inspiration inhibiting effect of etorphine-derivatives.
The inspiration inhibiting vagal reflex as elicited in rabbits by tracheal occlusion in inspiratory position, is strongly increased by etorphine and its derivatives, the 19-isoamylderivative benig of outstanding activity.
D000818:Animals; D005048:Etorphine / Q000031:analogs & derivatives / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D009019:Morphinans / Q000494:pharmacology*; D011817:Rabbits; D012018:Reflex / Q000187:drug effects; D012119:Respiration / Q000187:drug effects*; D013329:Structure-Activity Relationship; D014630:Vagus Nerve / Q000502:physiology
D009019:Morphinans; D005048:Etorphine