title: [Vitiligo in an pair of enzygotic twins].
abstract: Investigations of twins can contribute in the investigation of hereditary factors participating in the etiopathogenesis of vitiligo. A 28-year-old pair of male twins are presented, whose monovularity was conclusively proved by a comparison of morphological and serological features. Vitiligo developed as a concordant feature at the age of 13 and 22 years respectively. It is noticeable that there was a good concordance of the localisation of the vitiligo in both brothers. This concordance is most probably explained by genetic fixation of the disease, leading to the manifestation of vitiligo. Multifactoral heredity with threshold is discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D004200:Diseases in Twins; D005148:Facial Dermatoses / Q000235:genetics; D006229:Hand Dermatoses / Q000235:genetics; D006801:Humans; D008297:Male; D010388:Pelvis; D010409:Penile Diseases / Q000235:genetics; D014820:Vitiligo / Q000235:genetics*
vernacular_title: Vitiligo bei einem eineiigen Zwillingspaar