Inhibition of salicylate and lithium absorption in the human intestine by copper sulfate.
Copper sulfate, given orally in an emetic dose, decreased the absorption of therapeutic doses of acetylsalicylic acid or lithium carbonate, more than was expected judging from the recovery of salicylic acid in the vomit. Ten volunteers participated.
D000328:Adult; D001241:Aspirin / Q000378:metabolism* / Q000506:poisoning; D003300:Copper / Q000494:pharmacology* / Q000627:therapeutic use; D004639:Emetics / Q000627:therapeutic use; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects*; D008094:Lithium / Q000378:metabolism* / Q000506:poisoning; D011041:Poisoning / Q000188:drug therapy; D013431:Sulfates / Q000627:therapeutic use
D004639:Emetics; D013431:Sulfates; D003300:Copper; D008094:Lithium; D001241:Aspirin