The effect of triiodothyronine (T3) on calorigenic and thermoregulatory responses to noradrenaline in the rabbit.
Calorigenic action of NA administered to conscious rabbits was potentiated by the prior injection of triiodothyronine (T3). The increased NA-induced heat production in these rabbits, accompanied by higher increases in body temperature in spite of improved heat elimination, can be at least partly attributed to more intensive lipid mobilization and utilization. A considerable hyperglycemic effect of NA was found both in the control-untreated and T3-treated rabbits.
D000818:Animals; D001833:Body Temperature Regulation / Q000187:drug effects*; D004357:Drug Synergism; D004734:Energy Metabolism / Q000187:drug effects*; D005947:Glucose / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism / Q000494:pharmacology*; D011817:Rabbits; D014284:Triiodothyronine / Q000494:pharmacology*
D014284:Triiodothyronine; D005947:Glucose; D009638:Norepinephrine