title: [Induction of labor by prostaglandin F 2 alpha in the treatment of hydatidiform mole].
abstract: Labour was induced by intravenous infusion of prostaglandin F2alpha (PGF2alpha) in 12 patients with hydatidiform mole. After a mean infusion time of 15 h 51 min and a mean dosage of 25,1 mg PGF2alpha, the infusion of 5 to 40 mug PGF2alpha/min led to 1 to 3 cm dilatation of the cervix. In this way, it was possible to perform a mild evacuation of the molar tissue with vacuum curette or fixation forceps and curette. Under continued PG-infusion the uterus was contracted in the time of evacuation of hydatidiform mole. At present the preoperative dilatation of the cervix by means of PG-induced labour and vacuum curettage is the method of choice in the management of hydatidiform mole because of its effectiveness and few undesirable side effects.
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000188:drug therapy*; D007275:Injections, Intravenous; D007751:Labor, Induced; D007743:Labor, Obstetric / Q000187:drug effects*; D011247:Pregnancy; D011460:Prostaglandins F / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D011460:Prostaglandins F
vernacular_title: Weheninduktion mit Prostaglandin F2alpha zur Behandlung der Blasenmole