[Absorption studies with purines. Part 1: In vitro experiments with the Sartorius Absorption Model according to Stricker].
Various purines were investigated with the absorption model, according to Stricker, their kD-values calculated and compared with one another. The diffusion speed constants showed to be dependent upon the lipoid solubility and the polarity of the drugs. The experimental methods recommended by Stricker were analyzed.
D000042:Absorption; D002021:Buffers; D004058:Diffusion; D007408:Intestinal Absorption; D008055:Lipids; D008567:Membranes, Artificial; D008954:Models, Biological; D012995:Solubility; D014970:Xanthines / Q000378:metabolism*
D002021:Buffers; D008055:Lipids; D008567:Membranes, Artificial; D014970:Xanthines
Resorptionsstudien mit Purinen. 1. Mitteilung: In-vitro-Bestimmung mit dem Sartorius-Resorptionsmodell nach Stricker