[Cardiovascular effect of various morphine-line analgesics in rabbits anesthetized with thiopental or alphadione (Alfatesine)].
Alphadione (Alfatésine, Althesin, CT 1341), a steroid anaesthetic with a quick and short action, has but a very moderate analgesic activity, so it is necessary in human anaesthesian, to associate with it a morphinic analgesis systematically. Therefore it was interesting to study the response of cardiovascular system when using this type of association. Our results show that the cardiovascular depressive effects of morphinic analgesics, when they exist, are not increased by the presence of alphadione.
D000530:Alfaxalone Alfadolone Mixture / Q000494:pharmacology*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects*; D003916:Dextromoramide / Q000494:pharmacology; D005283:Fentanyl / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D008297:Male; D008614:Meperidine / Q000494:pharmacology; D011277:Pregnanediones / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D013874:Thiopental / Q000494:pharmacology*
D011277:Pregnanediones; D000530:Alfaxalone Alfadolone Mixture; D008614:Meperidine; D003916:Dextromoramide; D013874:Thiopental; D005283:Fentanyl
Effets cardiovasculaires de divers analgésiques morphinomimétiques chez le lapin anesthésié à l'aide de thiopental ou d'alphadione (Alfatésine)