[Search for a protein kinase specific for treponin T].
A specific to troponin T (as compared to f1 histone) proteinkinase is isolated using affinity chromatography on Sepharose 4B with covalently bound dephosphorylated troponin T. Homogeneous proteinkinase has a molecular weight of 175.000 and phosphorylates troponin T at a rate exceeding that of histone phosphorylation, while crude proteinkinase preparation has troponin T phosphorylation rate 15--20 times as low as that of histone phosphorylation. The enzyme isolated is capable of phosphorylating troponin T, but not troponin I, in the whole troponin complex.
D000818:Animals; D002384:Catalysis; D009124:Muscle Proteins; D009132:Muscles / Q000201:enzymology*; D011494:Protein Kinases / Q000302:isolation & purification*; D011817:Rabbits; D014336:Troponin
D009124:Muscle Proteins; D014336:Troponin; D011494:Protein Kinases
Poisk spetsificiheskoĭ k troponinu T proteinkinazy