[Mitochondrial morphology and metabolism in extrahepatic obstruction (author's transl)].
Corresponding to the increased activity of mitochondrial Glutamate-Dehydrogenase (GLDH) in serum in extrahepatic cholestasis a swelling of hepatic mitochondria could be shown on ultrastructural morphometric analysis. The morphometric alterations parallel the serochemical findings. A significant correlation could be calculated between the swelling of mitochondria and the activity of GLDH in serum.
D000818:Animals; D002779:Cholestasis / Q000201:enzymology / Q000473:pathology; D005969:Glutamate Dehydrogenase / Q000097:blood; D008930:Mitochondria, Liver / Q000201:enzymology / Q000648:ultrastructure; D008933:Mitochondrial Swelling; D051381:Rats
D005969:Glutamate Dehydrogenase
Mitochondrienmorphologie und Stoffwechsel bei extrahepatischer Obstruktion