title: [Sulpiride and psychic decompensation].
abstract: The use of sulpirid in psychiatry allows to delineate three types of activity of this compound which originality consists most in this triple association: neuroleptic activity, as well as anticonfusional and antidepressive. The psychodynamic and phenomenological evaluation of patients receiving a sulpirid treatment, has led us to consider the process of "psychic decompensation" as a target variable particularly sensitive to the action of this psychotropic drug. This process can be found in various pathological states--acute delirious states, depressive episodes, anxiety, autism, stress situation--where sulpirid acts, beside its specific thymoanaleptic or neuroleptic properties, through a "aspecific recompensation activity". This translates, psychopathologically, the action of sulpirid on the vegetative brain as well as the anti-stress properties of this psychrotropic drug, as verified in animal experiment.
mesh_terms: D001007:Anxiety / Q000188:drug therapy; D001321:Autistic Disorder / Q000188:drug therapy; D003072:Cognition Disorders / Q000188:drug therapy; D003863:Depression / Q000188:drug therapy; D006801:Humans; D011618:Psychotic Disorders / Q000188:drug therapy*; D013469:Sulpiride / Q000627:therapeutic use*
chemical_list: D013469:Sulpiride
vernacular_title: Le sulpiride et la décompensation psychique