[Experimental trichinasis (IV), study of the action of cyclophosphamide on the transplantation of 18 days old adults of T. spiralis (author's transl)].
The survival and the transplantation of adult trichinae collected in cyclophosphamide treated and untreated mice were studied. 1) The worms'burden harbored by treated mice on the 18th day after the infestation is from 4 to 5 times higher than in untreated ones. The sex ratio is here around one instead of 1/2 in the control lot of mice. 2) The female worms parasitic in treated mice continue to lay larvae. When these adult are transplanted in the gut of treated mice they seem give a greater number of larvae than if they are put in the gut of normal mice.
D000818:Animals; D003520:Cyclophosphamide / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D012744:Sex Ratio; D014234:Trichinella / Q000254:growth & development; D014235:Trichinellosis / Q000276:immunology / Q000469:parasitology*
D003520:Cyclophosphamide
Trichinose expérimentale. (4e note) Etude de l'action du cyclophosphamide sur la transplantation de Trichinella spiralis adultes âgées de 18 jours