title: [Absorption studies with purines. Part 2. In vitro experiments with a diffusion apparatus (author's transl)].
abstract: Various purines were investigated with the Desaga Resomat II, their diffusion speed constants calculated according to Stricker and compared with one another. The drugs investigated showed a proportinal relationship between diffusion speed and lipoid solubility. The effect of different membranes on the absorption experiments, with and without applied alternating pressure, was investigated. The results from the Sartorius Absorption Model and the Desaga Resomat II were compared.
mesh_terms: D000042:Absorption; D004058:Diffusion; D066298:In Vitro Techniques; D007408:Intestinal Absorption; D008055:Lipids; D008567:Membranes, Artificial; D008954:Models, Biological; D012995:Solubility; D014970:Xanthines / Q000378:metabolism*
chemical_list: D008055:Lipids; D008567:Membranes, Artificial; D014970:Xanthines
vernacular_title: Resorptionsstudien mit Purinen. 2. Mitteilung: In-vitro-Bestimmung mit dem Resomat II nach Dibbern