title: Pulmonary function in perlite workers.
abstract: Pulmonary function was studied in 117 men employed in three plants engaged in the mining and processing of perlite. Of these, 38 had been employed for ten years or more; 18 for 15 years or more and four men for 20 years or more. Review of chest films confirmed previous studies which showed no changes indicative of pneumoconiosis. Measurement of forced vital capacity (FVC) by Jones Pulmonor and by Collins 9-liter spirometer did not show reductions correlated with length of exposure, after effects of cigarette smoking had been taken into account. There was instead a slight increase in FVC associated with years in the perlite industry. The distribution of individuals with FVC below 80% of predicted also showed no association with duration of perlite exposure. Although there were slight reductions in forced expiratory volume in one second (FEV1) and in FEV1/FVC% which were associated with years in the perlite industry and which could not be explained by cigarette smoking, these reductions were not statistically significant. In summary, the population of men available for study in the major perlite-producing area of the United States, who have worked for periods up to 23 years, showed no evidence of pneumoconiosis by chest radiography or by measurement of forced vital capacity. Nevertheless, continued control of dust to ensure exposures below nuisance dust levels is essential. Medical surveillance should also continue with records being retained for periodic reevaluation.
mesh_terms: D000328:Adult; D000537:Aluminum Oxide; D000538:Aluminum Silicates / Q000009:adverse effects*; D003120:Colorado; D004417:Dyspnea / Q000209:etiology; D004781:Environmental Exposure; D005541:Forced Expiratory Volume; D005898:Glass; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009516:New Mexico; D009787:Occupational Medicine; D009790:Occupations; D010808:Physical Examination; D011859:Radiography; D012119:Respiration / Q000187:drug effects*; D012822:Silicon Dioxide; D012907:Smoking / Q000503:physiopathology; D013147:Spirometry; D013997:Time Factors; D014797:Vital Capacity
chemical_list: D000538:Aluminum Silicates; C003076:Perlite; D012822:Silicon Dioxide; D000537:Aluminum Oxide