[Coronary artery spasm induced by the somministration of ergonovine maleate in subjects with spontaneous angina (author's transl)].
In 6 patients affected by spontaneous angina with S-T elevation and coronariographic findings of obstruction, intravenous administration of ergonovine maleate determined the same clinical and ECG patterns of spontaneous episodes. The coronary arteriography during pain showed a marked spasm with occlusion of a large coronary vessel in four patients. In 2 patients with atypical chest pain and normal coronariogram, E.M. did not induce pain, ECG abnormality or coronariographic alterations. The role of spasm in spontaneous angina is discussed.
D000328:Adult; D000787:Angina Pectoris / Q000175:diagnosis*; D000788:Angina Pectoris, Variant / Q000139:chemically induced / Q000175:diagnosis*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000139:chemically induced / Q000175:diagnosis*; D004562:Electrocardiography; D004874:Ergonovine / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013035:Spasm / Q000139:chemically induced / Q000175:diagnosis*
D004874:Ergonovine
Spasmo coronarico indotto dalla somministrazione di ergonovina maleato in soggetti affetti da angina spontanea