Platelet survival in childhood idiopathic thrombocytopenic purpura in remission.
Mean platelet survival was significantly decreased (P less than 0.01) in three children with chronic and five children with acute ITP in remission. Sera from these patients sensitized normal platelets, as demonstrated by increased phagocytosis by autologous granulocytes. These results may suggest that the remission in some patients with ITP is obtained by compensatory platelet production.
D000208:Acute Disease; D000293:Adolescent; D001792:Blood Platelets; D002470:Cell Survival; D002648:Child; D002908:Chronic Disease; D006801:Humans; D011696:Purpura, Thrombocytopenic / Q000097:blood*; D012075:Remission, Spontaneous