title: Genetic recombination of precociousness and anticoccidial drug resistance in Eimeria tenella.
abstract: Two strains of Eimeria tenella differing in decoquinate-resistance and developmental rate were crossed. Strain Wis-F was decoquinate-sensitive (DS) and precocious (P+), while strain 368 was decoquinate-resistant (DR) and had a normal developmental rate (P-). Cultures of the parent strains and a culture derived from a mixture of parent strain oocysts were propagated through drug and developmental barriers to select parasites with the respective parental phenotypes (DS/P + and DR/P-) and the recombinant phenotype (DR/P+). The ability of a portion of the population in the strain-cross culture to reproduce in the presence of simultaneously imposed drug and developmental barrier showed that they were the recombinant phenotype (DR/P+), which had been produced through fertilization by gametes of opposite parent strains of E. tenella.
mesh_terms: D000818:Animals; D002645:Chickens / Q000469:parasitology; D003433:Crosses, Genetic; D003667:Decoquinate / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004539:Eimeria / Q000187:drug effects / Q000254:growth & development; D006912:Hydroxyquinolines / Q000494:pharmacology*; D010641:Phenotype; D011995:Recombination, Genetic
chemical_list: D006912:Hydroxyquinolines; D003667:Decoquinate