[Studies of lipoprotein lipase activity and adipocyte characteristics in the human: effect of obesity and diabetes (author's transl)].
Adipose tissue lipoprotein lipase activity (LPLA) and cellularity have been studied in controls, in diabetic or non-diabetic obese subjects and in insulin dependent diabetic patients. LPLA is increased in diabetic or non-diabetic obese subjects and in insulin dependent diabetic patients. LPLA is increased in diabetic or non-diabetic obese subjects (p less than 0.02) and decreased in insulin dependent diabetic patients (p less than 0.02). Adipocyte size is larger in obese subjects, whether diabetic or not (p less than 0.05). As defined by LPLA and cell size means, the different groups are related linearly. The implications of this relationship between LPLA and adipocyte size are considered.
D000273:Adipose Tissue / Q000201:enzymology* / Q000378:metabolism; D000293:Adolescent; D000328:Adult; D003920:Diabetes Mellitus / Q000201:enzymology*; D006801:Humans; D008071:Lipoprotein Lipase / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000201:enzymology*
D008071:Lipoprotein Lipase
Etude de l'activité de la lipoproteine-lipase et de la cellularité au niveau du tissu apideux humain: influence de l'obésité et du diabète