The effect of standing and exercise on plasma catecholamines, serum insulin, and serum gastrin.
Glucose-stimulated insulin secretion was measured in six normal subjects in the resting supine position, during standing, and during a period of moderate exercise in the supine position. Plasma noradrenaline averaged 0.26 ng/ml in the supine, resting position and rose to 0.57 and 0.61 ng/ml at the end of the standing experiment and the exercise period, respectively. Plasma adrenaline was unchanged in the standing position but rose threefold during exercise (to 0.09 ng/ml). Serum gastrin tended to decrease in all three experiments after the injection of glucose. Glucose-stimulated insulin secretion was the same during the first 10 min after the injection of glucose in the three experiments. It is concluded that a moderate increase in adrenergic activity has no influence on glucose-stimulated insulin secretion.
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D004837:Epinephrine / Q000097:blood*; D005755:Gastrins / Q000097:blood*; D005947:Glucose / Q000494:pharmacology; D006801:Humans; D007328:Insulin / Q000097:blood* / Q000378:metabolism; D000078790:Insulin Secretion; D008297:Male; D009638:Norepinephrine / Q000097:blood*; D005082:Physical Exertion; D011187:Posture
D001786:Blood Glucose; D005755:Gastrins; D007328:Insulin; D005947:Glucose; D009638:Norepinephrine; D004837:Epinephrine