Lymphocytopoiesis in vitro. Production of small lymphocytes and plasma cells in the isolated perfused spleen.
The production of small lymphocytes and mature plasma cells could be shown in the isolated perfused pig spleen using labelling with 3H-TdR. Within the first day the labelling index for lymphocytes increased to up to 10% and the labelling index for mature plasma cells to up to 60%.
D000818:Animals; D000921:Antibody-Producing Cells / Q000502:physiology; D006410:Hematopoiesis; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000378:metabolism; D008938:Mitosis; D010477:Perfusion; D010950:Plasma Cells / Q000378:metabolism; D013154:Spleen / Q000166:cytology / Q000502:physiology*; D013552:Swine; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors
D013936:Thymidine