Effect of administration of a single dose of testosterone oenanthate on constituents of human seminal plasma and serum gonadotropins.
Testosterone oenanthate was administered intramuscularly in six infertile men with oligozoospermia and its effects on serum gonadotropins and some constituents in the seminal plasma were studied. One week after injection the mean serum FSH level was decreased to about 50%. Serum LH levels did not change. The mean ornithine decarboxylase activity in human semen was increased by 100% after the testosterone administration. The androgen dependent nature of ODC, fructose and sialic acid have been demonstrated.
D002951:Citrates / Q000378:metabolism; D005640:Follicle Stimulating Hormone / Q000097:blood; D005632:Fructose / Q000378:metabolism; D006065:Gonadotropins, Pituitary / Q000097:blood*; D006801:Humans; D007273:Injections, Intramuscular; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008320:Maltose / Q000378:metabolism; D009845:Oligospermia / Q000378:metabolism*; D009955:Ornithine Decarboxylase / Q000378:metabolism; D012661:Semen / Q000032:analysis; D012794:Sialic Acids / Q000378:metabolism; D013081:Sperm Motility / Q000187:drug effects; D013739:Testosterone / Q000008:administration & dosage / Q000494:pharmacology*
D002951:Citrates; D006065:Gonadotropins, Pituitary; D012794:Sialic Acids; D005632:Fructose; D013739:Testosterone; D008320:Maltose; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D009955:Ornithine Decarboxylase