title: Sampling the fetoplacental circulation. I. The pregnant ovine.
abstract: Intrauterine endoscopy (fetoscopy) was successfully accomplished in 26 specially prepared pregnant sheep at 85 to 110 days' gestational age, with the use of a conventional 2.7 mm. Hopkins straightforward wide-angle telescope (Stortz 27018A) encased in a prototype 3.1 mm. eccentric cannula which incorporates a 25 gauge needle channel. Fetal blood was aspirated in 12 lambs. Twenty-five animals were followed throughout the remainder of pregnancy: nine (36 per cent) aborted within three days-three weeks after endoscopy. The pregnant ovine appeared to be a useful experimental animal model for the development of an intrauterine endoscopy technique.
mesh_terms: D000022:Abortion, Spontaneous / Q000209:etiology; D000818:Animals; D004724:Endoscopy / Q000009:adverse effects; D005260:Female; D005312:Fetal Blood; D005333:Fetus / Q000502:physiology*; D005865:Gestational Age; D008954:Models, Biological; D011247:Pregnancy; D011270:Pregnancy, Animal; D012756:Sheep / Q000502:physiology