HLA-B27 antigen in diagnosis of atypical seronegative inflammatory arthropathy.
Eighteen patients with an inflammatory pauciarticular peripheral arthropathy not typical of any known entity showed an asymmetrical pattern of disease, with a predilection for the lower extremities. Destructive joint changes and deformities were absent (mean follow-up 10 years). Although spondylitis and sacroiliitis were absent on x-rays, HLA-B27 antigen was found in 8 patients (44%). This antigen and similar joint symptoms are also found in other forms of arthritis.
D001168:Arthritis / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005188:False Negative Reactions; D006680:HLA Antigens / Q000032:analysis*; D006649:Histocompatibility Antigens / Q000032:analysis*; D006801:Humans
D006680:HLA Antigens; D006649:Histocompatibility Antigens