Bacterial flora in relation to cataract extraction. IV. Postoperative inflammation. The role of conjunctival bacteria and certain surgical factors.
In 499 patients operated on for cataract, the clinical postoperative signs of extraocular inflammation (conjunctival hyperaemia, chemosis, discharge and oedema of the lids), the number of infiltrates around the corneoscleral sutures, and the severity of intraocular inflammation in the anterior chamber (aqueous-flare) were assessed on the fourth postoperative day and correlated with the bacterial conjunctival flora examined both qualitatively and quantitatively on the same day. Patients with potential pathogens (Staphylococcus aureus, gram-negative bacilli and streptococci) on the conjunctiva following operation did not show any increased inflammatory reactions when compared with those without such pathogen. The quantity of bacteria, i.e. number of colonies, did not appear to play a role. The reasons are discussed. The clinical postoperative inflammatory signs were further correlated with the following factors: surgical complications, quality of suturing technique, use of alpha chymotrypsin, systemic disease, sex and age. A positive correlation was found between the severity of extraocular inflammation and retained lens material and hyphaema. Furthermore, extraocular reactions were more severe in males than in females. The incidence of infiltrates around corneoscleral sutures was found to vary with age, i.e. occurred more frequently in patients less than 60 years. No relationship was found between the severity of aqueous-flare and the above mentioned factors.
D000368:Aged; D002387:Cataract Extraction; D003228:Conjunctiva / Q000382:microbiology*; D003352:Corynebacterium / Q000302:isolation & purification; D005128:Eye Diseases / Q000209:etiology / Q000382:microbiology*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000209:etiology / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000382:microbiology*; D013210:Staphylococcus / Q000302:isolation & purification; D013291:Streptococcus / Q000302:isolation & purification; D013530:Surgical Wound Infection / Q000382:microbiology; D013537:Sutures