Pilocarpine ocular inserts.
Pilocarpine was administered to a selected group of ocular hypertensive subjects in the form of a synthetic biosoluble matrix inserted into the conjunctival cul-de-sac. Satisfactory lowering of the intraocular pressure resulted, with a minimum of subject intolerance. The decreased pressure response was significant in some cases for greater than 24 hours. Drug delivery by soluble inserts offers promise as a convenient and effective mode of therapy.
D000287:Administration, Topical; D003692:Delayed-Action Preparations; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D010862:Pilocarpine / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use
D003692:Delayed-Action Preparations; D010862:Pilocarpine