Anti-heart autoantibodies in ischaemic heart disease patients.
One hundred and ninety-nine ischaemic heart disease (IHD) patients were studied with regard to the prevalence of anti-heart autoantibodies (AHA). The incidence of AHA in IHD patients was 1%: one out of 102 patients who suffered acute myocardial infarction (AMI), one out of seventy-two patients who suffered from acute coronary insufficiency (ACI), and none out of twenty-five patients with other signs and symptoms of IHD, had AHA in their sera. An additional 2% of patients who suffered from AMI developed detectable antibody levels during a follow-up period of 15 days. In comparison,, 53% of patients (eight out of fifteen) who underwent heart surgery and who had no AHA prior to operation, developed these antibodies in their sera during 1-2 weeks following operation.
D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000032:analysis*; D003327:Coronary Disease / Q000276:immunology*; D005260:Female; D006331:Heart Diseases / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000276:immunology; D009206:Myocardium / Q000276:immunology*; D012214:Rheumatic Heart Disease / Q000276:immunology; D013997:Time Factors
D001323:Autoantibodies