title: Further experimental and clinical experience with aluminum oxide endoprostheses.
abstract: This paper describes the design principles of a new endoprosthesis made of dense aluminum oxide (A12O3) and implanted without bone cement. Mechanical tests and animal experiments have proved the sufficient mechanical strength of the bone-prosthesis connection as well as the biocompatibility of the material. So far, 12 tumor patients selected according to strict indication criteria have been operated on. Both the clinical-radiologic and the first histological findings available are encouraging. Special reference is made to the first fully ceramic total hip joint endoprostheses implanted in a human without bone cement.
mesh_terms: D000535:Aluminum; D000818:Animals; D001842:Bone and Bones / Q000033:anatomy & histology / Q000601:surgery; D002516:Ceramics; D004285:Dogs; D006615:Hip / Q000601:surgery; D006801:Humans; D007595:Joint Prosthesis; D019736:Prostheses and Implants
chemical_list: D000535:Aluminum