A Swiss family showing independent segregation of the Lutheran and Swann genes.
A family is reported in which the parents' mating is of the 'double back-cross' type with respect to the Sw, Lu and Se genes. The inheritance of these genes in the children shows, with reference to a possible linkage between Sw and the two other loci, four non-recombinants and three recombinants (or vice versa). The inheritance of the Lu and Se genes shows the well-known linkage between these two loci, with no instance of recombination. It is concluded that there is no evidence for close linkage between Sw and Lu-Se, and that the suggestion of a Sw-Lu linkage found in a family studied previously was due to chance.
D001789:Blood Group Antigens; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D008188:Lutheran Blood-Group System; D008297:Male; D010375:Pedigree; D011995:Recombination, Genetic; D013557:Switzerland
D001789:Blood Group Antigens; D008188:Lutheran Blood-Group System