Preparation of isolated intestinal villi useful for studying hydrolysis rates of penicillin and cephalosporin esters.
A method for the preparation of freeze-dried intestinal villi from hamsters and mice is described. The villi, consisting largely of epithelial cells rich in esterase activity, are useful for hydrolysis studies of penicillin and cephalosporin esters.
D000818:Animals; D002511:Cephalosporins / Q000378:metabolism*; D006224:Cricetinae; D004952:Esters; D005612:Freeze Drying; D006868:Hydrolysis; D007413:Intestinal Mucosa / Q000166:cytology* / Q000378:metabolism; D008297:Male; D008647:Mesocricetus; D008722:Methods; D051379:Mice; D010406:Penicillins / Q000378:metabolism*
D002511:Cephalosporins; D004952:Esters; D010406:Penicillins