Adverse drug reactions leading to hospitalization in children.
During a three-year period of prospective epidemiologic surveillance for adverse drug reactions in a pediatric population, 72 (2.0%) of 3,556 medical admissions were the result of adverse drug reactions. Antineoplastic drugs were most frequently cited as causing a reaction leading to admission. Approximately 40% of the reactions were severe, and four reactions contributed to death.
D000293:Adolescent; D000741:Anemia, Aplastic / Q000139:chemically induced; D000970:Antineoplastic Agents / Q000009:adverse effects; D001855:Bone Marrow Diseases / Q000139:chemically induced*; D002648:Child; D002673:Child, Hospitalized; D002675:Child, Preschool; D004071:Digitalis Glycosides / Q000506:poisoning; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D005431:Florida; D006760:Hospitalization; D006801:Humans; D007049:Iatrogenic Disease; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D013920:Thrombocythemia, Essential / Q000139:chemically induced
D000970:Antineoplastic Agents; D004071:Digitalis Glycosides