title: [Use of alloplastic material on the extrahepatic bile ducts].
abstract: Dogs (20 kg body weight) were laparotomized and the choledochous duct was ligated. Pre- and postoperative laboratory-parameters such as bilirubin, GOT, GPT, and alcaline phosphatase were controlled. Then, 8 days later, a patch-widening-plasty was performed after incision of the stenosis in 10 dogs. In the 10 other dogs the stenosis was resected and the defect was bridged over with a Teflon prosthesis. A few days later laboratory parameters became normal. Histologic investigation showed that after 4 weeks the Teflon prosthesis was covered with a bile duct-epithelial layer. In one of 3 patients with normal laboratory findings who have a Teflon patch, the operation took place 2 years ago.
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D003135:Common Bile Duct / Q000601:surgery*; D003251:Constriction, Pathologic / Q000601:surgery; D004285:Dogs; D008026:Ligation; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications; D019736:Prostheses and Implants; D000637:Transaminases / Q000097:blood
chemical_list: D011138:Polytetrafluoroethylene; D000637:Transaminases; D000469:Alkaline Phosphatase
vernacular_title: Verwendung von alloplastischem Material an den extrahepatischen Gallenwegen