title: Treatment for trichuriasis with oxantel.
abstract: Single doses of oxantel given to 24 children and 37 adults with light to moderate infections of Trichuris trichiura effected cures in 20 of 26 (77%) trials with 10 mg/kg body weight, in 23 of 25 (92%) with 15 mg/kg, and in 10 of 10 trials with 20 mg/kg. In cases not cured, the egg-counts were reduced 50% to 91%. Side effects were not observed, and no drug-associated changes were detected by biochemical, hematologic, and urine examinations before and after treatment.
mesh_terms: D000293:Adolescent; D000328:Adult; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D005243:Feces / Q000469:parasitology; D006801:Humans; D011715:Pyrantel / Q000031:analogs & derivatives; D011743:Pyrimidines / Q000008:administration & dosage / Q000627:therapeutic use*; D013343:Styrenes / Q000008:administration & dosage / Q000627:therapeutic use; D014257:Trichuriasis / Q000188:drug therapy* / Q000469:parasitology; D014258:Trichuris
chemical_list: D000871:Anthelmintics; D011743:Pyrimidines; D013343:Styrenes; D011715:Pyrantel; C003407:oxantel