Isolation of a new peptide antibiotic complex, B-43 (studies on antibiotics from the genus Bacillus. XV).
A new peptide antibiotic complex B-43, active against Gram-positive and Gram-negative bacteria, was isolated from a strain of Bacillus circulans. This antibiotic contains aspartic acid, valine, isoleucine, leucine, phenylalanine and 2,4-diaminobutyric acid. It seems to be related to polypeptin and antibiotic complex 4205, but differs in that it contains aspartic acid residue.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000096:biosynthesis / Q000494:pharmacology; D001407:Bacillus / Q000166:cytology / Q000378:metabolism* / Q000502:physiology; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005285:Fermentation; D051379:Mice; D010452:Peptide Biosynthesis; D010455:Peptides / Q000032:analysis / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D010455:Peptides