Synthesis of N-acetylcysteine compounds.
The preparation of some anilides, esters and amides of N-acetyl and N,S-diacetyl-cysteine is described. Of the compounds synthesized, particular interest was aroused by the p-hydroxyanilide derivatives of N-acetyl and N,S-diacetyl-L-cysteine owing to their analgesic, antiinflammatory and antipyretic activity.
D000111:Acetylcysteine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D000577:Amides / Q000138:chemical synthesis; D000700:Analgesics / Q000138:chemical synthesis; D000813:Anilides / Q000138:chemical synthesis; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis; D004952:Esters / Q000138:chemical synthesis; D051379:Mice; D051381:Rats
D000577:Amides; D000700:Analgesics; D000813:Anilides; D000893:Anti-Inflammatory Agents; D004952:Esters; D000111:Acetylcysteine