title: Neural mediation of compensatory adrenal growth.
abstract: Spinal cord hemisection between T2 and T3 inhibits compensatory adrenal growth when the contralateral but not the ipsilateral adrenal is removed (p less than 0.01). Pretreatment of left adrenals with 1 or 2% lidocaine, but not with saline, before removal inhibits compensatory right adrenal growth that is normally observed at 12 h (p less than 0.01). These results provide further functional evidence that both afferent and efferent neural elements mediate adrenal growth after unilateral adrenalectomy.
mesh_terms: D000311:Adrenal Glands / Q000187:drug effects / Q000254:growth & development*; D000315:Adrenalectomy; D000818:Animals; D008012:Lidocaine / Q000494:pharmacology; D008297:Male; D009929:Organ Size; D051381:Rats; D013116:Spinal Cord / Q000502:physiology*
chemical_list: D008012:Lidocaine