[Effect of gamma irradiation on the production and degradation system of the second hormonal messenger (author's transl)].
Gamma irradiation of rat liver plasma membranes leads to a decrease of the adenylcyclase activities stimulated by glucagon and fluoride. The observed inhibition is more important for the activity stimulated with glucagon. The 5'-nucleotisade activity is not changed by irradiation. When the phosphodiesterase system is submitted to gamma irradiation, the radiosensibility of enzymatic complex is more important.
D000262:Adenylyl Cyclases / Q000378:metabolism / Q000528:radiation effects*; D000818:Animals; D002462:Cell Membrane / Q000528:radiation effects; D005459:Fluorides / Q000494:pharmacology; D005720:Gamma Rays; D005934:Glucagon / Q000494:pharmacology; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000528:radiation effects*; D051381:Rats
D005934:Glucagon; D000262:Adenylyl Cyclases; D005459:Fluorides
Effets de l'irradiation gamma sur les systèmes de production et de dégradation du 2e messager hormonal