Sorbistin, a new aminoglycoside antibiotic complex of bacterial origin. III. Structure determination.
The structures of sorbistins A1, A2, B, C and D have been determined including stereo-chemistry. Sorbistins A1, A2 and B are composed of a 4-acyl-amino-4-deoxy-D-glucose and 1,4-diamino-1,4-dideoxy-D-sorbitol, the latter compound being hitherto undescribed in literature. Sorbistins C and D have the same aglycone of 1,4-diamino-1,4-dideoxy-D-sorbitol, which is linked with D-glucose and 4-amino-4-deoxy-D-glucose, respectively, through a glycosidic bond.
D000617:Aminoglycosides / Q000032:analysis* / Q000138:chemical synthesis; D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000138:chemical synthesis; D055598:Chemical Phenomena; D002621:Chemistry; D006868:Hydrolysis; D008968:Molecular Conformation
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents