[Investigations in streaming blood of the alert animal and man. II. Investigations on the mechanism of water resorption from the gut into the portal vein blood in the rat (author's transl)].
Arteriovenous differences (AVD) of electrolyte concentration in the gut are followed by continuous conductometry of ultrafiltrates of portal venous and aortic blood. Intraduodenal application of tap water amounting to 0.5, 1,0 or 2,0% body weight lead to extremely variable reactions both in time course and dimension of AVD. Whereas large and fast changes can be described by a single exponential term, small and slow changes show saturation effects. Evidence is presented, that these differences correspond to permeability changes, both for water in the direction: lumen to blood and for electrolytes in the direction: blood to lumen. Thirst has an enhancing effect on AVD. A dual resorptive pathway is proposed to fit the data.
D000818:Animals; D001012:Aorta, Abdominal; D003217:Conductometry / Q000379:methods; D004573:Electrolytes / Q000097:blood*; D005260:Female; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000378:metabolism; D011169:Portal Vein; D051381:Rats; D014462:Ultrafiltration / Q000379:methods; D014867:Water / Q000378:metabolism*; D014868:Water Deprivation
D004573:Electrolytes; D014867:Water
Untersuchungen im strömenden Blut wacher Versuchstiere und des Menschen. II. Untersuchungen zum Resorptionsmechanismus von Wasser aus dem Darm in das Blut der V. portae bei der Ratte