An electrophoretic polymorphism in the serum transferrins of Praomys (Mastomys) natalensis.
Three serum transferrin phenotypes of Praomys (Mastomys) natalensis, and African rodent having a high incidence of many varieties of spontaneous neoplasms, were detected by electrophoresis and autoradiography. On electrophoresis, transferrin of Trf-K was found to be a protein that migrates slowly toward the cathode, whereas that of Trf-M migrates rapidly. Trf-KM is a heterozygous phenotype of the above two. Progeny testing demonstrated that these three serum transferrin phenotypes in Mastomys are probably controlled by two codominant allelic genes, Trfk and Trfm, at a single autosomal locus. The genotypes of these phenotypes may be Trfk/Trfk, Trfm/Trfm, and Trfk/Trfm.
D000818:Animals; D004586:Electrophoresis; D005260:Female; D005787:Gene Frequency; D005796:Genes; D008297:Male; D011110:Polymorphism, Genetic; D012377:Rodentia / Q000097:blood*; D014168:Transferrin / Q000032:analysis*
D014168:Transferrin