[Psychological-experimental study on the effects of tranquilizers (diazepam and a drug under investigation) considering personality variables (author's transl)].
Three doses of a substance from the thieonodiazepine series (BAY g 5653), a drug under investigation, were tested as well as 5 mg of diazepam and a placebo, including a condition with no medication. 180 healthy male student volunteers, previously classified according to emotional stability/lability, took part in the study following a double-blind procedure. All subjects received white noise discontinuously with an intensity of 95 dBA. From the subjective and objective test variables employed, only the results from an adjective check list were evaluated fro the present paper. Diazepam showed some typical but not very strong effects. BAY g 5653 showed also little difference from placebo. There were some positive effects in the group of emotionally stable under stress.
D001143:Arousal / Q000187:drug effects; D003975:Diazepam / Q000494:pharmacology*; D004644:Emotions / Q000187:drug effects*; D005120:Extraversion, Psychological; D006801:Humans; D008297:Male; D009622:Noise; D010551:Personality; D013315:Stress, Psychological; D014149:Tranquilizing Agents / Q000494:pharmacology*
D014149:Tranquilizing Agents; D003975:Diazepam
Experimentalpsychologische Untersuchung zur Wirkung von Tranquilizern (Diazepam und einer Prüfsubstanz) unter Berücksichtigung von Persönlichkeitsmerkmalen