title: Individual differences in the antidiuretic response induced by single doses of 1-deamino-8-D-arginine-vasopressin (DDAVP) in patients with pituitary diabetes insipidus.
abstract: Marked interindividual differences were found in the height and duration of the antidiuretic action induced by increasing single intravenous doses (0.5 mug and 8 mug) of DDAVP in patients with pituitary diabetes insipidus. It was assumed that differences in the duration of action reflected individual variations in the rate of removal of vasopressin.
mesh_terms: D003894:Deamino Arginine Vasopressin / Q000378:metabolism / Q000627:therapeutic use*; D003919:Diabetes Insipidus / Q000188:drug therapy* / Q000503:physiopathology; D004231:Diuresis / Q000187:drug effects*; D014644:Genetic Variation; D006801:Humans; D013997:Time Factors; D014667:Vasopressins / Q000031:analogs & derivatives*
chemical_list: D014667:Vasopressins; D003894:Deamino Arginine Vasopressin