Effect of delta-THC on ethanol withdrawal in mice.
Delta-THC (10 mg/kg, i.p.) administered to mice immediately after withdrawal from a 3-day exposure to ethanol vapor was found to intensify withdrawal reactions. No effect was seen when delta-THC was administered chronically during the exposure to ethanol.
D000437:Alcoholism; D000818:Animals; D002188:Cannabis / Q000494:pharmacology*; D013759:Dronabinol / Q000494:pharmacology*; D000431:Ethanol / Q000097:blood; D006801:Humans; D008297:Male; D051379:Mice; D011720:Pyrazoles; D013375:Substance Withdrawal Syndrome
D011720:Pyrazoles; D000431:Ethanol; D013759:Dronabinol