[Multiple adenomatous papillary colonic polyps in a family with frequent cases of stomach carcinoma--a new phenotype of familial colonic polyposis].
A kindred of "minor adenomatous polyposis" associated with a high incidence of gastric cancer is described. Five out of 14 mainly asymptomatic individuals in 2 generations of kindred examined clinically, by panendoscopy and coloscopy exhibited multiple polyps of colon or/and stomach and jejunum. Single or multiple papillary adenomas were detected mainly in the right or middle colon (3 times or in the jejunum (once). Hyperplastic polyps were found in the stomach (3 times) and in the colon (twice of these 5 individuals. Our findings suggest that "minor adenomatous polyposis" associated with gastric cancer may represent another, hitherto unrecognized, phenotype of familial multiple polyposis.
D003108:Colonic Diseases / Q000150:complications / Q000235:genetics*; D005260:Female; D006801:Humans; D007417:Intestinal Polyps / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D013274:Stomach Neoplasms / Q000150:complications / Q000235:genetics*
Multiple adenomatöse papilläre Kolon-polypen in einer Familie mit gehäuftem Magenkarzinom-ein neuer Phänotyp der familiären Kolonpolypose?