Rotavirus infection in lambs: studies on passive protection.
Gnotobiotic lambs were protected against rotavirus infection by the presence in the gut at the time of infection of colostrum or serum containing antibodies to rotavirus. This protection was observed even when passively-acquired antibody was not present in the serum of the infected lamb. Infection under these conditions may have conferred immunity to subsequent challenge.
D000818:Animals; D000831:Animals, Newborn; D000914:Antibodies, Viral / Q000032:analysis; D003126:Colostrum / Q000276:immunology; D003967:Diarrhea / Q000276:immunology / Q000517:prevention & control*; D005243:Feces / Q000382:microbiology; D005856:Germ-Free Life; D007106:Immune Sera / Q000032:analysis; D007112:Immunity, Maternally-Acquired; D007116:Immunization, Passive; D007074:Immunoglobulin G / Q000032:analysis; D012328:RNA Viruses / Q000276:immunology / Q000302:isolation & purification; D012756:Sheep; D014777:Virus Diseases / Q000276:immunology / Q000517:prevention & control*
D000914:Antibodies, Viral; D007106:Immune Sera; D007074:Immunoglobulin G