The effect of coumarin on the liver weight of thermally injured rats.
Coumarin (a benzo-pyrone) has been shown to significantly increase liver weights 2 days after its injection. It is believed that coumarin belongs to a group of reticulo-endothelial system stimulants which increase the numbers of phagocytosing sites by increasing the number of phagocytic cells.
D000818:Animals; D002056:Burns; D003374:Coumarins / Q000494:pharmacology*; D005260:Female; D008099:Liver / Q000187:drug effects*; D012157:Mononuclear Phagocyte System / Q000187:drug effects; D009929:Organ Size; D010587:Phagocytosis / Q000187:drug effects; D051381:Rats
D003374:Coumarins