[Experimental demonstration of an identic antigenicity of the inner ear and kidney (author's transl)].
An allergic glomerunephritis was produced in rats by injection of an anti-basement-membrane-serum (IgG-fraction), taken from rabbits which were sensitized against a basement membrane fraction of rat-glomerula. Tissues from heart, liver, brain, lung and inner ear were compared with the well known alterations of the glomerula. Exclusively in stria vascularis and renal glomerula heavy changements of the basement membranes and endothelial cells could be shown by electronmicroscopic examination and by immunohistological methods.
D000818:Animals; D000906:Antibodies; D000941:Antigens; D001485:Basement Membrane / Q000276:immunology; D003429:Cross Reactions; D004432:Ear, Middle / Q000276:immunology* / Q000648:ultrastructure; D007678:Kidney Glomerulus / Q000276:immunology* / Q000648:ultrastructure; D051381:Rats
D000906:Antibodies; D000941:Antigens
Experimenteller Beweis einer gemeinsamen Antigenizität zwischen Innenohr und Niere