Stimulation by adenine of uridine uptake in cultured mammalian cells.
Adenine and its related compounds stimulated the incorporation of [3H]-uridine both into acid-soluble and insoluble fractions of cultured rat liver cells. The incorporation of [3H]-thymidine or -leucine was not affected by the addition of adenine. Rate of RNA synthesis as measured by [32P]-incorporation was not increased by adenine.
D000225:Adenine / Q000494:pharmacology*; D000241:Adenosine / Q000494:pharmacology; D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D002478:Cells, Cultured; D006151:Guanosine / Q000494:pharmacology; D012313:RNA / Q000096:biosynthesis; D051381:Rats; D014529:Uridine / Q000378:metabolism*
D006151:Guanosine; D012313:RNA; D000255:Adenosine Triphosphate; D000225:Adenine; D000241:Adenosine; D014529:Uridine