hnRNA in HeLa cells: distribution of transcript sizes estimated from nascent molecule profile.
In HeLa cells, about half the hnRNA is synthesized from transcription units which are less than 5000 bases in length, although over 80% is larger than the average mRNA. This conclusion was derived from a quantitative analysis of the nascent chain sedimentation profile.
D002499:Centrifugation, Density Gradient; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D006367:HeLa Cells; D009691:Nucleic Acid Denaturation; D012334:RNA, Neoplasm / Q000032:analysis / Q000096:biosynthesis* / Q000378:metabolism; D014158:Transcription, Genetic
D012334:RNA, Neoplasm; D004121:Dimethyl Sulfoxide