Hormonal regulation of male reproduction (with reference to infertility in man).
In mammals, pituitary control of spermatogenesis varies with age. In the rat, before puberty FSH is highly active whereas LH is not; after puberty it seems that LH alone is able to support spermatogenesis. The mode of action of hormones is discussed. In the human, in case of infertility due to hypogonadotrophic hypogonadism, spermatogenesis can be restored by HCG or HMG. The best results are obtained after simultaneous treatment with both hormones, LH activity being predominant.
D000367:Age Factors; D000818:Animals; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D005640:Follicle Stimulating Hormone / Q000502:physiology*; D006801:Humans; D007006:Hypogonadism / Q000188:drug therapy; D007248:Infertility, Male / Q000188:drug therapy; D007986:Luteinizing Hormone / Q000502:physiology*; D008297:Male; D008596:Menotropins / Q000627:therapeutic use; D051381:Rats; D013091:Spermatogenesis
D006063:Chorionic Gonadotropin; D008596:Menotropins; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone