[Familial granulomatous disease: histopathological and histogentic data].
The lesions seen in chronic familial granulomatosis are variable and seen in varied combinations: granulomas, often disseminated, pseudotuberculous lesions, histiocytes with a high content in lipofuscins seen in the liver, lymph nodes, spleen and lungs in particular. These lesions may be explained at least in part by a congenital defect in leucocytes, which is peculiar to this hereditary disease, and which concernes bactericidal functions.
D006105:Granulomatous Disease, Chronic / Q000235:genetics / Q000473:pathology*; D006801:Humans; D007962:Leukocytes / Q000276:immunology; D010585:Phagocyte Bactericidal Dysfunction / Q000473:pathology*
La maladie granulomateuse familiale données histopathologiques et histogénétiques