title: [Volume and pressure changes due to nitrousoxide diffusion in costumary and in low-pressure cuffs of endotracheal tubes (author's transl)].
abstract: Changes of volume and pressure due to N2O-diffusion into PVC and Latex cuffs of endotracheal tubes were measured. Endotracheal tubes with a small-volume cuff (Magill and Portex) and one type of a large-volume, low-pressure cuff (Lanz) were examined. Within 48 h significant changes of volume and pressure were registered at different starting volumes and different N2O-concentrations. In the small-volume cuffs of the Portex and Magill tubes very high pressures were always noted; increases of volume were always seen, which were accompanied by increases, in some cases also by decreases of pressure. In the large-volume cuffs of the Lanz tube there were increases of volume and pressure; the measured pressures where however, in a clinical unimportant range. These changes are caused by N2O-diffusion into the cuff, slowed N2-diffusion out of the cuff, prestretching of the cuff membrane by the starting volume and further stretching by N2O diffusing into the cuff. These measurements are of practical clinical significance: This high-pressures due to starting volume and N2O-diffusion in small-volume cuffs explains the higher rate of trauma to the trachea, even after short term intubation, in contrast to the extremely low pressures in large-volume, low-pressure cuffs.
mesh_terms: D004058:Diffusion; D007442:Intubation, Intratracheal / Q000295:instrumentation*; D009584:Nitrogen; D009609:Nitrous Oxide; D011312:Pressure
chemical_list: D009609:Nitrous Oxide; D009584:Nitrogen
vernacular_title: Volumen- und Druckänderungen durch Lachgas-Diffusion in herkömmlichen und Niederdruck-Blockungsmanschetten von Endotrachealtuben