title: Immediate relief of symptoms during acute attacks of Meniere's disease, using a pressure chamber.
abstract: Five patients with Meniere's disease were exposed to underpressure in a pressure chamber while suffering from acute attacks with vertigo, nausea, tinnitus and fullness of the ear. Spontaneous nystagmus was the objective criterion for the selection of suitable cases. Subjective as well as objective symptoms subsided much faster than they do with other kinds of treatment. Four patients were free from symptoms within 40 minutes, while the fifth case still complained of vertigo, tinnitus and fullness of the ear after the treatment. However, the symptoms were less severe. A mechanism is discussed by means of which an ambient pressure decrease might cause a reduction of the endolymphatic volume, thus relieving acute symptoms of Meniere's disease.
mesh_terms: D000208:Acute Disease; D000328:Adult; D001273:Atmosphere Exposure Chambers; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000628:therapy*; D008875:Middle Aged; D009325:Nausea / Q000628:therapy; D013997:Time Factors; D014012:Tinnitus / Q000628:therapy; D014717:Vertigo / Q000628:therapy