title: The diagnosis and treatment of amenorrheas.
abstract: Correct diagnosis and treatment of amenorrhea is a challenging problem to the clinician. A systematic approach to the differential diagnosis and treatment, based on functional activity along the hypothalamic-pituitary-ovarian axis, is presented. By obtaining a detailed history, performing a meticulous physical examination, and utilizing several simple clinical and laboratory tests, a correct diagnosis can be reached for the majority of patients. Treatment is relatively simple and geared to the patient's desires. In most instances, understanding of the basic problem helps the patient to cope with it and no treatment is needed. If lack of menses is a problem, cyclic bleeding at regular intervals can be induced. When fertility is a problem, ovulation can be induced, provided that there is no ovarian failure. By spending sufficient time with the patient, paying attention to detail, and giving some thought, a correct diagnosis can be reached and adequate treatment given to most amenorrheic patients.
mesh_terms: D000568:Amenorrhea / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D000856:Anorexia Nervosa / Q000175:diagnosis; D003277:Contraceptives, Oral, Combined / Q000009:adverse effects; D003937:Diagnosis, Differential; D004107:Dilatation and Curettage / Q000009:adverse effects; D012734:Disorders of Sex Development / Q000175:diagnosis; D004700:Endocrine System Diseases / Q000175:diagnosis; D005260:Female; D005836:Genitalia, Female / Q000002:abnormalities; D006801:Humans; D010049:Ovarian Diseases / Q000175:diagnosis; D011555:Pseudopregnancy
chemical_list: D003277:Contraceptives, Oral, Combined