title: Platelet production capacity at intervals after acute thrombocytopenia.
abstract: Platelet producing capacity was examined at intervals after acute platelet depletion by reinduction of acute thrombocytopenia and assessment of the subsequent platelet recovery rates of 35S-sulfate incorporation into platelets. Platelet producing capacity was increased on days 1 and 2, somewhat decreased on days 3 and 4 and had returned to baseline by day 5. These studies suggest that there is an initial increase followed by a decrease on days 3 and 4 in cells which can respond to thrombopoietic stimulating factor after induction of acute thrombocytopenia.
mesh_terms: D000208:Acute Disease; D000818:Animals; D001772:Blood Cell Count; D001792:Blood Platelets / Q000276:immunology / Q000378:metabolism / Q000502:physiology; D006410:Hematopoiesis; D007106:Immune Sera; D008297:Male; D051381:Rats; D013431:Sulfates / Q000097:blood; D013921:Thrombocytopenia / Q000097:blood*; D013997:Time Factors
chemical_list: D007106:Immune Sera; D013431:Sulfates