[Propane-diol-(1.3) fatty acid esters as metabolites of postmortal triglyceride catabolism (author's transl)].
The investigation of 72 samples of human subcutaneous fat tissue stored in closed small bottles at room temperature showed that every third sample decomposed with the formation of unknown metabolites. The presence of these compounds could already be recognized in the crude lipid extracts by characteristic 1H-NMR signals, increasing in intensity with time of storage. After isolation, the unknown metabolites could be identified as di- or mono fatty acid esters of propane-diol-(1.3). Thus, the known scheme of postmortal breakdown of triglycerides is to be supplemented by a further remarkable pathway.
D000273:Adipose Tissue / Q000378:metabolism / Q000473:pathology; D004952:Esters / Q000378:metabolism; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011180:Postmortem Changes; D011409:Propylene Glycols / Q000378:metabolism*; D014280:Triglycerides / Q000378:metabolism*
D004952:Esters; D011409:Propylene Glycols; D014280:Triglycerides
Propandiol-(1.3)-fettsäureester als Metaboliten der postmortalen Fettspaltung