Pulmonary fine structural changes in children with tissue hypoxia.
Six children have undergone lung biopsy for evaluation of fine structure. Four children demonstrated increased DAVO2 preoperatively and had marked ultrastructural changes in their lungs. Such changes appear to result from embolization of microthrombi or microaggregates to the lung from under-oxygenated tissue.
D000293:Adolescent; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D006330:Heart Defects, Congenital / Q000473:pathology; D006801:Humans; D000860:Hypoxia / Q000473:pathology*; D007223:Infant; D008168:Lung / Q000648:ultrastructure*; D011658:Pulmonary Fibrosis / Q000473:pathology