title: Lymphocytopoiesis in vitro. Production of small lymphocytes and plasma cells in the isolated perfused spleen.
abstract: The production of small lymphocytes and mature plasma cells could be shown in the isolated perfused pig spleen using labelling with 3H-TdR. Within the first day the labelling index for lymphocytes increased to up to 10% and the labelling index for mature plasma cells to up to 60%.
mesh_terms: D000818:Animals; D000921:Antibody-Producing Cells / Q000502:physiology; D006410:Hematopoiesis; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000378:metabolism; D008938:Mitosis; D010477:Perfusion; D010950:Plasma Cells / Q000378:metabolism; D013154:Spleen / Q000166:cytology / Q000502:physiology*; D013552:Swine; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors
chemical_list: D013936:Thymidine