The production of calcification in connective tissue and skeletal muscle using various chemical compounds.
The subcutaneous injection into mice of small quantities of lead salts resulted in calcification of the dorsal fascia. Other reputed calcergens failed to produce a similar reaction. However, the injection of Zn Cl2 and KMn O4 in high doses caused damage to, and subsequent calcification of the panniculus carnosus muscle.
D000818:Animals; D002114:Calcinosis / Q000139:chemically induced*; D005205:Fascia / Q000187:drug effects*; D007854:Lead / Q000494:pharmacology; D008297:Male; D051379:Mice; D009132:Muscles / Q000187:drug effects*; D011196:Potassium Permanganate / Q000494:pharmacology; D012492:Salts; D015032:Zinc / Q000494:pharmacology
D012492:Salts; D011196:Potassium Permanganate; D007854:Lead; D015032:Zinc