Antilipidemic drugs. Part 3: On the synthesis of 14C-radiolabelled isopropyl-[4'-chlorobenzoyl)-2-phenoxy-2-methyl]-propionate (LF-178).
Isopropyl-[4'-(p-chlorobenzoyl)-2-phenoxy-2 methyl]-propionate (LF 178; procetofene; Lipanthyl¿) was labelled with 14C. The carbon atom of the ketone function was chosen for the study. The obtained product has a total specific radioactivity of 8.79 mCi/mM. Its structure was proved by NMR.
D002250:Carbon Radioisotopes; D000960:Hypolipidemic Agents / Q000138:chemical synthesis*; D007553:Isotope Labeling / Q000379:methods; D011422:Propionates / Q000138:chemical synthesis*
D002250:Carbon Radioisotopes; D000960:Hypolipidemic Agents; D011422:Propionates