The effect of amitrole (3-amino-1H-1,2-4-triazole) on cytokinin activity and sexual reproduction in the yeast Schizosaccharomyces octosporus.
Cytokinin activity in extracts from actively growing cultures of Schizosaccharomyces octosporus was greatly reduced by exposure to amitrole (5 X 10--3M). Amitrole treatment, at the same concentration, stimulated cell enlargment and ascus production in this organism. These data suggest that a relationship may exist between low levels of endogenous cytokinins, cell expansion in preference to cell division, and ascus formation.
D000640:Amitrole / Q000494:pharmacology*; D001203:Ascomycota / Q000187:drug effects*; D003583:Cytokinins / Q000096:biosynthesis*; D004305:Dose-Response Relationship, Drug; D010937:Plant Growth Regulators / Q000096:biosynthesis*; D012568:Schizosaccharomyces / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D014230:Triazoles / Q000494:pharmacology*
D003583:Cytokinins; D010937:Plant Growth Regulators; D014230:Triazoles; D000640:Amitrole