[Experimental results with different fractionation regimes and low-LET irradiation of mice (author's transl)].
The effect of several fractionation regimes was examined by the model of mammary tumour in C3H-mice. The best results were observed with several fractionations daily. No curative effect was obtained by means of a total dose of 6000 rd achieved with all fractionation regimes. The results of investigations underline the importance of considering cellular proliferation kinetic processes in malignant tumours in order to optimize the temporal distribution of radiation dose.
D000818:Animals; D002455:Cell Division / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D008325:Mammary Neoplasms, Experimental / Q000532:radiotherapy*; D051379:Mice; D008809:Mice, Inbred C3H; D011879:Radiotherapy Dosage
Ergebnisse tierexperimenteller Untersuchungen bei Anwendung unterschiedlicher Fraktionierungsrhythmen und Strahlenarten niedriger LET