Effect of long-chain acyl-CoA on the omega-oxidation of monocarboxylic acid.
In vitro addition of stearoyl-CoA in 10,000 x g supernatant of rat livers, first enhanced the rate of omega-oxidation of free [1-14C] stearate, until a concentration of the acyl-CoA reached to the same level of that of the substrate. Further addition of stearoly-CoA decreased gradually the oxidation rate.
D000818:Animals; D003065:Coenzyme A / Q000494:pharmacology*; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism; D010084:Oxidation-Reduction / Q000187:drug effects; D051381:Rats; D013229:Stearic Acids / Q000378:metabolism*
D013229:Stearic Acids; D003065:Coenzyme A