title: Growth hormone response in fetal alcohol syndrome.
abstract: In the fetal alcohol syndrome (FAS) there is severe physical growth retardation both prenatally and postnatally. Secretion of growth hormone (GH) after insulin-induced hypoglycaemia and arginine infusion was analysed in 5 cases of FAS to find out whether changes in GH secretion might account for the abnormal growth pattern. Results showed a normal or slight hyper-response of GH up to 150 ng/ml, and normal somatomedin activity in those blood samples with high GH level. It was concluded that the growth retardation in FAS is not caused by GH or somatomedin deficiencies.
mesh_terms: D000437:Alcoholism / Q000150:complications*; D001120:Arginine / Q000494:pharmacology; D001786:Blood Glucose / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D005315:Fetal Diseases / Q000097:blood / Q000209:etiology* / Q000652:urine; D005865:Gestational Age; D006130:Growth Disorders / Q000097:blood / Q000209:etiology* / Q000652:urine; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism*; D006801:Humans; D007223:Infant; D007328:Insulin / Q000494:pharmacology; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D013002:Somatomedins / Q000097:blood
chemical_list: D001786:Blood Glucose; D007328:Insulin; D013002:Somatomedins; D013006:Growth Hormone; D001120:Arginine