Deisovalerylblastmycin produced by Streptomyces SP.
A new antifungal antibiotic was isolated from the fermentation broth of Streptomyces sp. 5140-A1. Degradation studies of the crystalline antibiotic, m.p. 186 approximately 188 degrees C, C21H28O8N2, suggested Piricularia oryzae and less toxicity against killfish than antimycin A--blastmycin antibiotics.
D000818:Animals; D000968:Antimycin A / Q000031:analogs & derivatives* / Q000032:analysis / Q000096:biosynthesis / Q000633:toxicity; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005285:Fermentation; D005399:Fishes; D005658:Fungi / Q000187:drug effects; D007928:Lethal Dose 50; D051379:Mice; D013302:Streptomyces / Q000378:metabolism*
C013468:deisovalerylblastmycin; D000968:Antimycin A