[Hyperthyroidism by autonomous metastasis of thyroid carcinoma (author's transl)].
Nine years after surgical ablation of a trabeculo-vesicular carcinoma of the tyroid, a patient developped bone and liver metastasis. She had clinical signs of thyrotoxicosis, clear increase of blood T3 and sligh increase of T4. The TSH secretion was blocked. Exogenous TSH increased iodine uptake in the thyroid and not in the metastasis. After 2 doses of 120 mCi of 131I, she became hypothyroid, the liver was normal and the scan revealed the disappearance of uptake in thyroid and in metastasis. Such a clinical course was previously found in only 10 cases despite the frequent funcitonal differenciation of the metastasis of thyroid carcinomas.
D000230:Adenocarcinoma / Q000150:complications*; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000209:etiology*; D008875:Middle Aged; D009362:Neoplasm Metastasis; D013964:Thyroid Neoplasms / Q000150:complications*
Hyperthyroïdie par métastases autonomes et extinctives d'un cancer thyroïdien