title: [Breakdown of the herbicide pyramin by micro-organisms of the soil (author's transl)].
abstract: The herbicide Pyramin, which is employed in the cultivation of beets to combat broad-leaf weeds, contains the herbicidal substance 5-amino-4-chloro-2-phenyl-3 (2H) pyridazinone, abbreviated pyrazone. The breakdown of pyrazone in the soil was investigated and it was found that this substance disappears relatively quickly and that the dephenylated heterocycle of pyrazone 5-amino-4-chloro-3 (2H) pyridazinone is obtained as transformation product. It was possible to isolate bacteria, which grow on pyrazone as the only carbon source, from soil samples originating from different parts of the world. Four compounds are excreted during the cultivation of pyrazone-degrading bacteria in a pyrazone mineral salt medium. With the aid of the structure of these metabolites and enzymatic tests, a scheme for the bacterial breakdown of pyrazone is proposed.
mesh_terms: D001419:Bacteria / Q000378:metabolism*; D001673:Biodegradation, Environmental; D055598:Chemical Phenomena; D002621:Chemistry; D006540:Herbicides / Q000378:metabolism*; D011724:Pyridazines / Q000378:metabolism*; D012988:Soil Microbiology; D013696:Temperature
chemical_list: D006540:Herbicides; D011724:Pyridazines
vernacular_title: Der Abbau des Herbizids Pyramin durch Mikroorganismen des Bodens