title: Coccidioidomycosis of bone and joints.
abstract: Sixteen cases of coccidioidomycosis involving bone and joints were treated with Amphotericin B. In all systemic or disseminated cases Amphotericin B should be prescribed. Local Amphotericin B is useful in joints if the disease is limited, and in patients who do not tolerate Amphotericin B by systemic route. If the patient cannot be treated with systemic Amphotericin B, surgical treatment should be directed to remove all possible infected tissue. Patients with a negative skin test and albuminuria in disseminated coccidioidomycosis should be treated with Amphotericin B and passive immune transfer.
mesh_terms: D000293:Adolescent; D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use*; D001847:Bone Diseases / Q000175:diagnosis / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D003047:Coccidioidomycosis / Q000175:diagnosis / Q000188:drug therapy*; D003168:Complement Fixation Tests; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
chemical_list: D000666:Amphotericin B