title: Microperoxisome distribution in the central nervous system of the rat.
abstract: The distribution of microperoxisomes was studied in areas of the central nervous system having high concentrations of catecholaminergic neurons and in areas lacking this neuron type, using the alkaline DAB cytochemical method for catalase. Substantial numbers of microperoxisomes are found in neurons in the locus coeruleus and in nucleus A1 of the medulla, as well as in the substantia nigra, whereas few catalase-reactive bodies are seen in neurons of the cerebrum and cerebellum. The number of catalase-reactive microperoxisomes per unit area in the catecholaminergic neurons of the CNS is comparable to the number seen previously in neurons of the peripheral cervical sympathetic ganglia. Some spinal cord neurons also contain reactive microperoxisomes. Catalase-reactive microperoxisomes are numerous in oligodendrocytes of all areas studied, and in ependymal cells bordering the third and fourth ventricles. Astrocytes contain few reactive structures in the cytoplasm near the nucleus, but they are readily found in astrocytic processes and end-feet.
mesh_terms: D000818:Animals; D002374:Catalase / Q000032:analysis*; D002395:Catecholamines / Q000032:analysis; D002490:Central Nervous System / Q000201:enzymology / Q000648:ultrastructure*; D002552:Cerebral Ventricles / Q000201:enzymology / Q000648:ultrastructure; D004805:Ependyma / Q000201:enzymology / Q000648:ultrastructure; D005260:Female; D005725:Ganglia, Autonomic / Q000201:enzymology / Q000648:ultrastructure; D006651:Histocytochemistry; D008297:Male; D008830:Microbodies / Q000201:enzymology; D009836:Oligodendroglia / Q000201:enzymology / Q000648:ultrastructure; D009940:Organoids / Q000201:enzymology; D051381:Rats; D013116:Spinal Cord / Q000201:enzymology / Q000648:ultrastructure; D013378:Substantia Nigra / Q000201:enzymology / Q000648:ultrastructure
chemical_list: D002395:Catecholamines; D002374:Catalase