Abnormal or absent beta mRNA in betao Ferrara and gene deletion in delta beta thalassaemia.
In patients with betao thalassaemia from Ferrara, beta globin mRNA sequences are either absent or structurally abnormal while in betao thalassaemia in Catania, beta globin mRNA sequences are present. In deltabeta thalassaemia there is a deletion of beta-like globin genes, while in betao Catania DNA, no beta globin gene deletion is detectable.
D002648:Child; D002675:Child, Preschool; D002872:Chromosome Deletion; D005796:Genes; D006801:Humans; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger / Q000032:analysis / Q000172:deficiency / Q000378:metabolism*; D013789:Thalassemia / Q000235:genetics / Q000378:metabolism*
D012333:RNA, Messenger