[Effect of heparin on the lipid peroxidation reaction of erythrocytes and their stability].
Physiological concentration (10 units/ml) of heparin activates ascorbate-dependent lipid peroxidation of erythrocytes and reduces their stability in the citrate-phosphate buffer (pH 3.0). In a concentration of 100 units/ml heparin does not influence the thermal (62 degrees) oxidation of methyloleate. It follows that heparin is not direct prooxidant.
D004912:Erythrocytes / Q000378:metabolism*; D006493:Heparin / Q000494:pharmacology*; D006801:Humans; D009829:Oleic Acids / Q000378:metabolism*; D010084:Oxidation-Reduction; D013997:Time Factors
D009829:Oleic Acids; D006493:Heparin
Vliianie geparina na reaktsii perekisnogo okisleniia lipidov éritrotsitov i ikh ustoĭchivost'