title: Release of renal kallikrein to the perfusate by isolated rat kidney.
abstract: The addition of furosemide to the fluid used to perfuse isolated rat kidney increases the kallikrein activity found in the perfusion fluid. The experiments favour the concept that furosemide activates a kallikrein precursor or/and the synthesis and release of kallikrein in the kidneys.
mesh_terms: D000818:Animals; D005665:Furosemide / Q000494:pharmacology*; D007610:Kallikreins / Q000378:metabolism* / Q000652:urine; D007668:Kidney / Q000187:drug effects / Q000378:metabolism* / Q000502:physiology; D008297:Male; D051381:Rats
chemical_list: D005665:Furosemide; D007610:Kallikreins