[Systemic side effects of external corticoids: results of dermatologic studies in children with neurodermititis].
Of 111 children with atopic dermatitis who were admitted as in-patients in a German aero-biological childrens clinic, 83 patients (74.8%) had been prescribed a prolonged corticosteroid therapy from their family doctor. For 60 children (54.1%) the corticosteroid application was topital, partly with occlusive dressing or with fluorinated preparations. The remaining 23 children (20.7%) were treated topically and systemically with corticosteroids. Of the 60 children whose atopic dermatitis was treated exclusively with topical corticosteroids, 59 patients (98.3%) showed undesirable side effects. Moreover, irreversible body changes developed through the transcutaneous absorptive processes, which were more evident and appeared more often in girls than in boys.
D000287:Administration, Topical; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000009:adverse effects* / Q000627:therapeutic use; D002177:Candidiasis / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D003480:Cushing Syndrome / Q000209:etiology; D004487:Edema / Q000139:chemically induced; D005260:Female; D006130:Growth Disorders / Q000139:chemically induced; D006801:Humans; D008297:Male; D009450:Neurodermatitis / Q000188:drug therapy*; D011711:Pyoderma / Q000139:chemically induced
D000305:Adrenal Cortex Hormones
Systemische Nebenwirkungen durch Externkortikoide: Ergebnisse dermatologischer Untersuchungen an Kindern mit Neurodermitis