title: [A prospective study on the occurrence of postoperative thrombosis of leg-veins and the possible influence of aescin in its prevention (author's transl)].
abstract: Based on the frequency of subclinical, postoperative thrombosis which we detected using radio-iodine-tagged fibrinogen (125I-fibrinogen) in 2 comparable test groups of 100 female patients each, we were able to compare the effectiveness of Aescin (Reparil) to the untreated group. Whereas only 16 patients in the Reparil group were thrombose-positive we found 27 such cases in the control group. The analysis of these data shows Reparil to be of distinct advantage when compared to the untreated group.
mesh_terms: D000293:Adolescent; D000328:Adult; D001780:Blood Coagulation Tests; D002648:Child; D004341:Drug Evaluation; D004928:Escin / Q000627:therapeutic use*; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications; D012503:Saponins / Q000627:therapeutic use*; D013927:Thrombosis / Q000517:prevention & control*
chemical_list: D012503:Saponins; D004928:Escin; D005340:Fibrinogen
vernacular_title: Prospektive Untersuchung der Häufigkeit postoperativer Beinvenenthrombosen und ihre medikamentöse Beeinflussung durch Aescin