[Immunosuppressive activity of halothane. A study using the lymphoblastic transformation test (LTT)].
Halothane in concentration of 1p. 100 or 2p. 100 blocked DNA synthesis in lymphocytes cultured with 0.4 mg of PHA in seven subjects out of nine. Although statistically insufficient, these results confirm those of BRUCE, CULLEN and co workers, and thus demonstrate the immunodepressant properties of this saturated halogenated hydrocarbon.
D006221:Halothane / Q000276:immunology / Q000494:pharmacology*; D006801:Humans; D007166:Immunosuppressive Agents; D008213:Lymphocyte Activation
D007166:Immunosuppressive Agents; D006221:Halothane
Activité immuno-dépressive de l'halothane. Etude par test de transformation lymphoblastique (T.T.L.)