Pulmonary hypertension in relationship to acidaemia after maximum forced exercise. A further preliminary report.
Pulmonary hypertension was shown to occur in wild young zebra and wildebeest subject to forced exercise over 2 to 5 km distance. Measurements of pulmonary arterial pressure were made on a Devices recorder connected to a catheter passed via the jugular vein. Systemic pressure was recorded after puncture of the dorsal aorta. The electrocardiogram, PO2, PCO2 and pH were determined and enzyme levels such as CPK were estimated. Reduction of the pulmonary hypertension occurred after bicarbonate infusion.
D000138:Acidosis / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D001188:Artiodactyla / Q000502:physiology*; D001639:Bicarbonates / Q000627:therapeutic use; D006976:Hypertension, Pulmonary / Q000188:drug therapy / Q000662:veterinary*; D010527:Perissodactyla / Q000502:physiology*; D005082:Physical Exertion
D001639:Bicarbonates