title: [Research on nitrogen heterocyclic compounds. X. New method of synthesis of pyrrolo/1,2-a/quinoline and its derivatives].
abstract: The synthesis of pyrrolo[1,2-a]quinoline derivatives from 1-arylpyrroles bearing an acetic acid or acetonitrile moiety on the benzene or pyrrole nucleus is described. Pyrrolo [1,2-a]quinoline derivatives have some pharmaceutical interest as cyclic analogues of 9H-pyrrolo[1,2-a]indole and 5H-pyrrolo[2,1-c] [1,4]-benzodiazepine, the basic structures of the antitumor antibiotics mitomycin C, anthramycin and tomaymycin.
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis; D055598:Chemical Phenomena; D002621:Chemistry; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D009584:Nitrogen; D011804:Quinolines / Q000138:chemical synthesis*
chemical_list: D000970:Antineoplastic Agents; D006571:Heterocyclic Compounds; D011804:Quinolines; D009584:Nitrogen
vernacular_title: Ricerche su composti eterociclici azotati: Nota X-Un nuovo metodo di sintesi della pirrolo [1,2-a]chinolina e di suoi derivati