[Pharmacological study of a non-steroid compound with progestin-like activity (M.G. 6236)].
The detailed pharmacological study of 1-acetyl-4-phenylcyclohexanol (isomer with equatorial hydroxyl - M.G. 6236 - see formula) is reported. This compound was found to have progestin-like activity particularly as regards increase in carbonic anhydrase activity and increase in the proliferative activity of the mucosa of the rabbit uterus.
D000726:Androgen Antagonists; D000818:Animals; D003511:Cyclohexanols / Q000494:pharmacology*; D004971:Estrus / Q000187:drug effects; D005260:Female; D006062:Gonadotropins / Q000037:antagonists & inhibitors; D010060:Ovulation / Q000187:drug effects; D011247:Pregnancy; D045167:Progesterone Congeners / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D012890:Sleep / Q000187:drug effects; D014599:Uterus / Q000187:drug effects
D000726:Androgen Antagonists; D003511:Cyclohexanols; D006062:Gonadotropins; D045167:Progesterone Congeners
Studio farmacologico di un composto non steroideo ad attività progestinica (M.G. 6236)