[The immunobiological role of alloantigens of host tissue compatibility in the structure of oncornaviruses].
H-2 antigens of mouse cells were shown to be incorporated into the Rauscher virus virion structure. Alloantibody to these antigens neutralized the infectious activity of the virus. Active immunization of mice with H-2 alloantigens reduces susceptibility of the animals to the virus. The experimental results suggest that alloantigens of host tissue compatibility incorporated into the virion membrane determine important immuno-biological properties of Rauscher virus.
D000818:Animals; D000956:Antigens, Viral; D006649:Histocompatibility Antigens; D007114:Immunization; D007519:Isoantigens; D007942:Leukemia, Experimental / Q000517:prevention & control; D051379:Mice; D008815:Mice, Inbred Strains; D011925:Rauscher Virus / Q000276:immunology*; D013154:Spleen / Q000276:immunology
D000956:Antigens, Viral; D006649:Histocompatibility Antigens; D007519:Isoantigens
Ob immunobiologicheskoĭ roli alloantigenov tkanevoĭ sovmestimosti khoziaina v strukture onkornavirusov