Pure red cell aplasia.
The presentation and clinical course of pure red cell aplasia in 5 patients are described. In 3 of them no concomitant diseases were present, in 1 the condition was associated with the presence of a thymoma, and the remaining patient was suffering from a lymphocytic lymphoma. Pregnancy led to a recurrence of the disorder in 2 patients. The fact that 4 of the patients exhibited unequivocal evidence of other auto-immune disturbances adds further support to the concept that pure red cell aplasia itself has an auto-immune basis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000741:Anemia, Aplastic / Q000209:etiology* / Q000628:therapy; D001327:Autoimmune Diseases; D004912:Erythrocytes; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications; D008297:Male; D008875:Middle Aged; D009230:Myxedema / Q000150:complications; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic; D013945:Thymoma / Q000150:complications; D013953:Thymus Neoplasms / Q000150:complications