[Interferonogenic capacity of strains influenza B virus and their sensitivity to exogenous interferon].
This study is a continuation of the investgation of the influence of endogenous and exogenous interferon on influenza infection. Influenza B virus strains, both laboratory and fresh isolates, were found to be poor interferon inducers in contrast to influenza A virus strains. The study also showed that influenza B virus strains not only induced endogenous interferon poorly but were also resistant to exogenous interferon. This evidence points to marked differences of the investigated influenza B virus strains not only induced endogenous interferon poorly but were also resistant to exogenous interferon. This evidence points to marked differences of the investigated influenza B virus strains from influenza A virus strains which further indicates their peculiar nature.
D000818:Animals; D002642:Chick Embryo; D004352:Drug Resistance, Microbial; D007372:Interferons / Q000096:biosynthesis* / Q000494:pharmacology / Q000627:therapeutic use; D008168:Lung / Q000382:microbiology; D051379:Mice; D009975:Orthomyxoviridae / Q000187:drug effects; D009976:Orthomyxoviridae Infections / Q000188:drug therapy / Q000378:metabolism* / Q000382:microbiology; D013045:Species Specificity; D014776:Virus Cultivation; D014779:Virus Replication
D007372:Interferons
Interferonogennaia sposobnost' shtammov virusa grippa B i ikh chuvstvitel'nost' k ékzogennomu interferonu