title: Distribution of hereditary variants of haptoglobin and transferrin in several human populations in Siberia.
abstract: Haptoglobins and transferrins have been studied in nganasans from Taymir peninsula, in chelkantsi and kumandintsi from Altai and in 500 Russian inhabitants of Novosibirsk. Frequencies of Hp2 and TfB0-1 alleles in nganasams have been found to be the highest in the region. Transferrin polymorphism in the sample from Novosibirsk population seems to be maintained at the expense of four common alleles (C;B2;B0-1; DChi), in nganasans -- tow alleles (C and B0-1). No polymorphism has been observed in chelkantsi and kumandintsi. No rare transferrin variant has been found in the samples studied except homozygous B0-1 B0-1 in a child from nganasan family.
mesh_terms: D000483:Alleles; D055598:Chemical Phenomena; D002621:Chemistry; D005787:Gene Frequency; D006242:Haptoglobins / Q000032:analysis; D006801:Humans; D011110:Polymorphism, Genetic; D012800:Siberia; D014168:Transferrin / Q000032:analysis
chemical_list: D006242:Haptoglobins; D014168:Transferrin
vernacular_title: Raspredlenie nasledstvennykh variantov gaptoglobina i transferrina v nekotorykh populiatsiiakh cheloveka v Sibiri