title: [Possible incompatibility of deep radiotherapy and high-dose adriamycin or cyclophosphamide therapy in advanced genital tumors of the female].
abstract: A report is given of the treatment of three patients with advanced malignant tumors. Combined percutaneous irradiation and application of adriamycine produced severe side effects which, in one case, took a lethal end. A combination of relatively good tolerance consisting of an irradiation therapy and stosstherapy with cyclophosphamide is presented as an alternative treatment of the advanced ovarian carcinoma. The authors express a warning of simultaneous application of radiation and adriamycine therapy.
mesh_terms: D000293:Adolescent; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005833:Genital Neoplasms, Female / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000532:radiotherapy
chemical_list: D004317:Doxorubicin; D003520:Cyclophosphamide
vernacular_title: Mögliche Inkompatibilität von Tiefenbestrahlung und hochdosierter Adriamycin- oder Cyclophosphamid-Stosstherapie bei fortgeschrittenen Genitalmalignomen der Frau