Hypertrichosis lanuginosa in a mother and son.
Hypertrichosis lanuginosa (without gingival hyperplasia) is described in a mother and son; the latter also had photophobia, infantile genitalia, growth retardation, hypotension, low IQ and dental abnormalities (hyperdontia, permanence of deciduous and delayed eruption of permanent teeth). Both have normal dermatoglyphics. Some clinical findings are discussed. The presence of this syndrome in a mother and son supports an autosomal mode of inheritance (with variable expressivity). Hypertrichosis lanuginosa is a pure monomultidysplasia and may be classified with the tricho-odontic sub-group of the ectodermal dysplasias.
D000015:Abnormalities, Multiple / Q000235:genetics; D000328:Adult; D002648:Child; D003878:Dermatoglyphics; D005260:Female; D005886:Gingival Hypertrophy; D006801:Humans; D006983:Hypertrichosis / Q000235:genetics*; D008297:Male; D014071:Tooth Abnormalities / Q000235:genetics