[Pathology and immune lysis of cells infected with measles virus isolated from subacute sclerosing panencephalitis].
The Si strain isolated from a patient with subacute sclerosing panencephalitis like reference measles virus strains was shown to induce in cell cultures formation of symplasts and spindle-shaped cells, cytoplasmic and intranuclear inclusions, pathology of mitosis, appearance of intracellular and surface virus-induced antigens. The presence of the latter caused cell cytolysis under the effect of measles immune sera and complement.
D000956:Antigens, Viral / Q000032:analysis; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D003601:Cytotoxicity Tests, Immunologic; D006801:Humans; D007181:Inclusion Bodies, Viral; D008459:Measles virus / Q000254:growth & development* / Q000276:immunology / Q000302:isolation & purification; D013344:Subacute Sclerosing Panencephalitis / Q000382:microbiology
D000956:Antigens, Viral
Patologiia i immunnyĭ lizis kletok, zarazhennykh virusom kori, vydelennym pri podostrom skleroziruiushchem panétsefalite