[Double blind study of vitamin E compared to placebo in the prevention of anemia in the low birth weight infant during the 7th week of life: therapeutic study].
alpha-tocopherol and placebo were compared by a double-blind trial to study their preventive effect on secondary anemia in a sample of low birth weight (less than or equal 2,500 g) infants. In the 7th week of life, hematological data from each of the two groups of infants (receiving vitamin E or placebo) were compared either by covariance analysis or by the t test of comparison of means. The infants who were given vitamin E have a higher serum level of vitamin E, a lower hemolysis, a higher erythrocyte count and a higher hemoglobin level than infants given the placebo. No significant difference was observed with respect to hematocrit or reticulocyte count. Thus, it appears that vitamin E has an effect on some of the factors in the anemia of infants of low birth weight.
D000751:Anemia, Neonatal / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000517:prevention & control*; D008297:Male; D010919:Placebos; D014810:Vitamin E / Q000627:therapeutic use*
D010919:Placebos; D014810:Vitamin E
Comparaison en double aveugle de la vitamine e au placebo dans la prévention de l'anémie de l'enfant de faible poids de naissance a la 7e semaine de vie: essai thérapeutique