Nephrotic syndrome due to subacute glomerulonephritis -- association with hydrocarbon exposure?
A 59-year-old man developed a nephrotic syndrome 40 days after hydrocarbon exposure of 3 days' duration. Renal biopsy gave evidence of a subacute proliferative glomerulonephritis. A lasting remission was obtained with immunosuppressive therapy. The case history is discussed in the light of recent studies indicating a causal relationship between hydrocarbon exposure and glomerulonephritis. The reversible nature of the disease in the present case is discussed in relation to the disease in experimental animals induced by a single administration of heterologus antigen.
D004781:Environmental Exposure; D005921:Glomerulonephritis / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D006838:Hydrocarbons / Q000506:poisoning*; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D008875:Middle Aged
D006838:Hydrocarbons