Infectious mononucleosis. Death due to agranulocytosis and pneumonia.
Infectious mononucleosis (IM) is usually considered a benign disease. Agranulocytosis developed in a young college student 14 days after the onset of IM. Fulminant staphylococcal pneumonia and bilateral pulmonary infarcts resulted, and the patient died 4 1/2 hours after admission to a hospital. Agranulocytosis secondary to IM may be more prevalent than previously thought. A review of the literature indicated that infection developed in 57.9% of the patients with IM and extreme neutropenia and 45.4% of the infected patients died.
D000208:Acute Disease; D000328:Adult; D000380:Agranulocytosis / Q000209:etiology* / Q000473:pathology; D001344:Autopsy; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications* / Q000473:pathology; D008297:Male; D011023:Pneumonia, Staphylococcal / Q000209:etiology / Q000473:pathology; D011655:Pulmonary Embolism / Q000473:pathology; D012131:Respiratory Insufficiency / Q000150:complications