title: [Use of pyridoxylate for treating chronic coronary insufficiency].
abstract: A total of 49 patients with chronic ischaemic heart disease (38 of whom had previously survived myoca dial infarction) were treated with Piridoxylate administered intramuscularly and orally. The treatment resulted in an improvement of the state of 2/3 of the patients, positive ECG shifts, improvements of cardio- and haemodynamics at rest and under physical exercises. In half of the patients an increased tolerance of physical exercises was noted. No side-effects of Piridoxylate therapy were observed.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy; D001794:Blood Pressure / Q000187:drug effects; D002908:Chronic Disease; D003327:Coronary Disease / Q000188:drug therapy*; D004341:Drug Evaluation; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007273:Injections, Intramuscular; D007539:Isonicotinic Acids / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption / Q000187:drug effects; D011735:Pyridoxic Acid / Q000627:therapeutic use*; D012146:Rest
chemical_list: D007539:Isonicotinic Acids; D011735:Pyridoxic Acid
vernacular_title: Primenenie piridoksilata dlia lecheniia bol'nykh s khronicheskoĭ koronarnoĭ nedostatochnost'iu