title: An established cell line from the newt Notophthalmus viridescens.
abstract: An established cell line, derived from the dorsal iris of the eastern North American newt, Notophthalmus viridescens, is described. The cells display an epithelial-like behaviour in culture, grow relatively slowly, possess considerably larger chromosomes than mammals and are heteroploid, although some near-diploid cells are present in the culture. The line is characterized by a strong tendency to overlapping and aggregation in spite of its origin from adult tissue.
mesh_terms: D000818:Animals; D002449:Cell Aggregation; D002454:Cell Differentiation; D002455:Cell Division; D002460:Cell Line; D002462:Cell Membrane / Q000648:ultrastructure; D003260:Contact Inhibition; D004247:DNA / Q000378:metabolism; D004847:Epithelial Cells; D004848:Epithelium / Q000378:metabolism / Q000648:ultrastructure; D007498:Iris / Q000166:cytology; D011003:Ploidies; D012455:Salamandridae; D014562:Caudata
chemical_list: D004247:DNA