title: Masking level differences for cochlear and brain stem lesions.
abstract: Masking level differences (MLD) for 500 Hz pure tones and for spondees were obtained from 48 subjects. Twelve were without otologic or neurologic complaints (normal), 12 had high frequency, noise-induced hearing losses, 12 were diagnosed otologically as having Ménière's disorder, and 12 had neurologically diagnosed central nervous system (CNS) disorders. Results indicated that high frequency, noise-induced hearing losses do not affect MLD for 500 Hz stimuli, but do diminish the size of MLD for speech. Masking level differences for both 500 Hz and spondees were decreased for the Ménière's disorder group. The group of patients having CNS disorders attributed to multiple sclerosis, to inflammatory lesion of the pons, to degenerative processes of the cerebellum and adjacent nervous tissue, or to brain stem cerebrovascular accident had normal hearing according to conventional pure tone and speech testing, but attained smaller than normal MLD for 500 Hz and spondees. These findings agree closely with results obtained in an earlier study and continue to suggest that, given normal peripheral auditory function, MLD tests may have unique value in detection of subtle lesions of the central auditory nervous system.
mesh_terms: D001307:Auditory Perception; D001927:Brain Diseases / Q000503:physiopathology; D001933:Brain Stem / Q000503:physiopathology*; D003051:Cochlea / Q000503:physiopathology*; D006317:Hearing Loss, Noise-Induced / Q000175:diagnosis; D006801:Humans; D007759:Labyrinth Diseases / Q000503:physiopathology; D008575:Meniere Disease / Q000175:diagnosis; D009103:Multiple Sclerosis / Q000175:diagnosis; D010470:Perceptual Masking; D013997:Time Factors