Stimulation of food intake in horses by diazepam and promazine.
In two adult horses doses of 0.02-0.03 mg/kg diazepam, intravenously, increased 1 hr intake 54-75% above control levels. Intake was stimulated when the diet was a high grain, calorically dense one and also when the diet was a high fiber, calorically dilute one. Two young rapidly growing weanling horses showed an even more pronounced stimulation of intake. Following diazepam 1 hr intake was increased 105-240% above control lelvels. Promazine at a dose of 0.5 mg/kg also stimulated intake in adult horses, but not as markedly as did diazepam. A transquilizer and a neuroleptic appear to have a stimulatory eff upon short-term intake in horses.
D000367:Age Factors; D000818:Animals; D003975:Diazepam / Q000494:pharmacology*; D004032:Diet; D005247:Feeding Behavior / Q000187:drug effects*; D005260:Female; D006736:Horses / Q000502:physiology*; D008297:Male; D011395:Promazine / Q000494:pharmacology*; D013268:Stimulation, Chemical
D011395:Promazine; D003975:Diazepam