[Globulin producing cells in cultures of blast-transformed lymphocytes in vitro].
Globulin-producing cells -- lymphocytes, transitional transformed forms, blasts and plasmocyte-like cells were revealed with the aid of Coon's method in the culture of the human peripheral blood following stimulation with staphylococcus filtrate and phytohemagglutinin. Analysis of dynamics of the appearance of these cells suggests that they originate from a special B-lymphocyte subpopulation -- the immunological memory cells. Some of the globulin-producing cells arose from precursors without any division, in others differentiation was combined with proliferation.
D000328:Adult; D002478:Cells, Cultured; D005916:Globulins / Q000096:biosynthesis*; D006801:Humans; D037102:Lectins; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000378:metabolism*; D013210:Staphylococcus / Q000032:analysis
D005916:Globulins; D037102:Lectins
Globulinprodutsiruiushchie kletki v kul'turakh blasttransformirovannykh limfotsitov in vitro