[Role of facilitating antibodies during pregnancy and growth of tumors].
Maternal antibodies can be detected by immunofluorescence techniques on mouse placenta. Following acid elution, it is possible to characterize them as mostly IgG, mainly IgG1. It can be shown that they specifically bind paternal thymocytes and promote allogeneic mast cell degranulation, mainly specifically, but also to a lesser extent non specifically. The prolongation of survival of paternal strain tumor injected into a maternal strain animal demonstrate their enhancing activity.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D005260:Female; D006084:Graft Rejection; D007074:Immunoglobulin G / Q000032:analysis; D066298:In Vitro Techniques; D051379:Mice; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000276:immunology*; D010920:Placenta / Q000166:cytology / Q000276:immunology; D011247:Pregnancy; D014181:Transplantation Immunology; D014184:Transplantation, Homologous
D000906:Antibodies; D007074:Immunoglobulin G
Rôle des anticorps facilitants dans la grossesse et la prise des tumeurs