title: [Treatment of hyperuricaemia with a combination of allopurinol and benzbromaron (author's transl)].
abstract: Three patients with gout and seven with hyperuricaemia, previously untreated, took a single dose of 100 mg allopurinol and 20 mg benzbromaron (as a combined preparation) each morning. There occurred a highly significant decrease in serum uric acid concentration from 430.7 mumol/l (72.4 mg/l) to 268.6 mumol/l (45.2 mg/l), without any significant increase in urinary excretion of uric acid.
mesh_terms: D000493:Allopurinol / Q000008:administration & dosage / Q000627:therapeutic use*; D001553:Benzbromarone / Q000008:administration & dosage / Q000627:therapeutic use*; D001572:Benzofurans / Q000627:therapeutic use*; D004338:Drug Combinations; D006073:Gout / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D013997:Time Factors; D014527:Uric Acid / Q000097:blood
chemical_list: D001572:Benzofurans; D004338:Drug Combinations; D014527:Uric Acid; D001553:Benzbromarone; D000493:Allopurinol
vernacular_title: Behandlung der Hyperurikämie mit einer Kombination von Allopurinol und Benzbromaron