[Inhibition of cathepsins from trout muscle and from bovine spleen by proteinase inhibitors of potato tubers (author's transl)].
The cathepsins D from trout muscle and from bovine spleen, as well as cathepsin A from bovine spleen are inhibited by a crude proteinase inhibitor from potato tubers. Cathepsins C and B1 are not inhibited. It was shown by isoelectric focussing that several inhibitors for cathepsin D are present in potatoes. Those with isoelectric points at pH 9.2, 9.1, 9.0, 8.9, 8.5 inhibit cathepsins D both from trout muscle and from bovine spleen. In addition some inhibitors with isoelectric points at pH 6.6, 6.5, and 6.2 were observed, which inhibit cathepsin D from trout muscle only.
D000818:Animals; D002403:Cathepsins / Q000037:antagonists & inhibitors*; D002417:Cattle; D004791:Enzyme Inhibitors; D011480:Protease Inhibitors; D013154:Spleen / Q000201:enzymology; D014337:Trout
D004791:Enzyme Inhibitors; D011480:Protease Inhibitors; D002403:Cathepsins
Hemmung von Kathepsinen aus Forellenmuskel und aus Rindermilz durch Proteinaseninhibitoren der Kartoffel