[Testing of chemical substances, especially drugs, for carcinogenic activity in mammals (author's transl)].
Basing on recommandations given by international institutions and by individual experts and on our own experiences, general recommandations are submitted for the testing of substances for carcinogenic activity with particular respect to drugs and some problems related to the interpretation of the results are discussed.
D000818:Animals; D001947:Breeding; D002273:Carcinogens / Q000008:administration & dosage / Q000494:pharmacology*; D006224:Cricetinae; D051379:Mice; D009369:Neoplasms / Q000473:pathology; D009374:Neoplasms, Experimental / Q000139:chemically induced; D051381:Rats; D012737:Sex Factors; D013045:Species Specificity; D013997:Time Factors
D002273:Carcinogens
Testung von Substanzen auf kanzerogene Wirkung an Sügetieren, unter besonderer Berücksichtigung von Arzneimitteln