[The problem of sterility in men and women after wide area sub-diaphragmatic irradiation (author's transl)].
Sub-diaphragmatic irradiation in an upside down Y pattern for Hodgkin's disease results in sterility in the women. Protection consists of irradiating the lumbar chain only when possible or by displacement of the ovary before irradiation, and laterally for preference. Although subsequent pregnancy is then possible, the genetic risk remains. In the male, Y irradiation results in prolonged virtually complete azoospermia. Associated chemotherapy also causes definitive sterility in the male. Collection for a sperm bank before treatment is advised.
D000008:Abdominal Neoplasms / Q000532:radiotherapy*; D000328:Adult; D005260:Female; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D007247:Infertility, Female / Q000209:etiology*; D007248:Infertility, Male / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010053:Ovary / Q000528:radiation effects*; D011832:Radiation Injuries; D013737:Testis / Q000528:radiation effects*
Problèmes de stérilité chez l'homme et la femme après irradiation par grand champ sous-diaphragmatique