title: Lessening of adverse biochemical effects of shock in newborn puppies by general anesthesia.
abstract: A shock preparation has been developed which produces the expected anaerobic metabolism in neonatal beagle puppies less than 7 days old. Lactic acid production was found to be significantly higher in shocked puppies operated upon under local anesthesia than when the same procedures were performed in shocked puppies under general endotracheal anesthesia. These findings suggest that general anesthesia may be safer in the very sick human neonate.
mesh_terms: D000768:Anesthesia, General / Q000009:adverse effects*; D000772:Anesthesia, Local / Q000009:adverse effects; D000818:Animals; D000831:Animals, Newborn; D001786:Blood Glucose; D004195:Disease Models, Animal; D004285:Dogs; D007773:Lactates / Q000097:blood; D011188:Potassium / Q000097:blood; D012771:Shock, Hemorrhagic / Q000378:metabolism*
chemical_list: D001786:Blood Glucose; D007773:Lactates; D011188:Potassium