D-xylose absorption and jejunal morphology in African patients with pellagra (niacin tryptophan deficiency).
D-xylose absorption tests and jejunal morphology have been shown to be unaltered in 12 African patients with pellagra when compared with normal values for Zambian Africa adults; that result is contrary to two previous investigations in India and Egypt respectively. A significant inverse association has been shown, however, between D-xylose absorption and serum immunoglobulin IgG and IgA concentrations; that is consistent with previous studies and probably reflects malabsorption of xylose in the presence of systemic infections. It is concluded that pellagra per se does not alter intestinal structure or monosaccharide absorption.
D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007408:Intestinal Absorption; D007583:Jejunum / Q000473:pathology*; D010383:Pellagra / Q000276:immunology / Q000378:metabolism / Q000473:pathology*; D014994:Xylose / Q000378:metabolism*; D015024:Zambia
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D014994:Xylose