Antibodies sequestered in the liver granulomata of 8-week infections of CF1 mice by Schistosoma mansoni Sambon, 1907.
With our methods IgM, 7Sgamma1 and C3 were detected in the egg-induced liver granulomata of 8-week infections of CF1 mice by Schistosoma mansoni. It is speculated that, in addition to sequestration of antigens within these lesions by these antibodies, 7Sgamma1 may be associated with the Hoeppli phenomenon, and IgM in combination with C3 may be responsible for the ultimate death of the embryo or miracidium within the egg shell.
D000818:Animals; D000906:Antibodies / Q000032:analysis*; D003176:Complement C3 / Q000032:analysis; D005260:Female; D006099:Granuloma / Q000276:immunology*; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis; D008109:Liver Diseases, Parasitic / Q000276:immunology*; D051379:Mice; D012552:Schistosomiasis / Q000276:immunology*
D000906:Antibodies; D003176:Complement C3; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins