The nuclear fibrous lamina in human cells: studies on its appearance and distribution.
The nuclear fibrous lamina, a structure of unknown function, is situated at the nuclear periphery directly apposed to the inner nuclear membrane. Although it has been well described in invertebrate and many non-human vertebrate cells, its occurrence in human tissue has not been emphasized. This survey of a large variety of human cells has documented the lamina to be present, although of varying thickness, in a large number of cell types. It is consistently thickest in mesenchymal or mesenchymally derived cells and its appearance and thickness is not correlated with pathologic alterations.
D001853:Bone Marrow / Q000648:ultrastructure; D001854:Bone Marrow Cells; D002467:Cell Nucleus / Q000648:ultrastructure*; D006801:Humans; D007668:Kidney / Q000166:cytology; D008099:Liver / Q000166:cytology; D009685:Nuclear Envelope / Q000648:ultrastructure; D012867:Skin / Q000166:cytology