Detection and characterization of circulating immune complexes in rheumatoid arthritis.
Circulating immune complexes (IC) were detected and quantified in serum of patients with rheumatoid arthritis (RA) by three methods: radiolabeled Clq binding test, anticomplementary activity and optical density of 3% PEG precipitated sera. Rheumatoid factor (RF) is characterized in PEG precipitates by the Waaler-Rose reaction. The relationship between IC, complement and RF levels are analyzed.
D000936:Antigen-Antibody Complex; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D003176:Complement C3; D003181:Complement C4; D003165:Complement System Proteins; D006801:Humans; D012217:Rheumatoid Factor
D000936:Antigen-Antibody Complex; D003176:Complement C3; D003181:Complement C4; D003165:Complement System Proteins; D012217:Rheumatoid Factor