title: Double bond position affects metabolism of cis-Octadecenoates.
abstract: The metabolic fate of cis-positional isomers of octadecenoates has been compared to that of naturally occurring oleic acid (cis-delta9). Radioactive mixtures of tritium-labeled positional octadecenoate isomer and oleic acid-10(-14)C were administered to laying hens, and their eggs were analyzed for the isotopic ratios (3H/14C) incorporated into total egg lipid, triglycerides, and phospholipids. Variations in the isotopic ratios indicated the comparative metabolic utilization of cis-positional isomers delta8 through delta12. Incorporation into egg lipid fractions is as follows: triglycerides: delta9 greater than delta8, delta9 greater than delta10, delta9 greater than delta11, delta9 greater than 12; phospholipid: delta9 greater than delta8, delta9 greater than delta10, delta9 less than delta11, delta9 less than delta12.
mesh_terms: D000818:Animals; D002645:Chickens; D004530:Egg Yolk; D005260:Female; D008055:Lipids / Q000096:biosynthesis*; D009829:Oleic Acids / Q000378:metabolism*; D010058:Oviposition; D010063:Ovum / Q000378:metabolism*; D010743:Phospholipids / Q000096:biosynthesis*; D013329:Structure-Activity Relationship; D014280:Triglycerides / Q000096:biosynthesis*
chemical_list: D008055:Lipids; D009829:Oleic Acids; D010743:Phospholipids; D014280:Triglycerides