title: hnRNA in HeLa cells: distribution of transcript sizes estimated from nascent molecule profile.
abstract: In HeLa cells, about half the hnRNA is synthesized from transcription units which are less than 5000 bases in length, although over 80% is larger than the average mRNA. This conclusion was derived from a quantitative analysis of the nascent chain sedimentation profile.
mesh_terms: D002499:Centrifugation, Density Gradient; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D006367:HeLa Cells; D009691:Nucleic Acid Denaturation; D012334:RNA, Neoplasm / Q000032:analysis / Q000096:biosynthesis* / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D012334:RNA, Neoplasm; D004121:Dimethyl Sulfoxide