title: Sudden deafness. A histopathological study.
abstract: Histopathological studies were performed in the temporal bones from a 77-year-old woman who had bilateral sudden deafness 31 years before her death. The common findings in both cochleas were atrophy of the organ of Corti and stria vascularis, and degeneration of the tectorial membrane. Pathology of the tectorial membrane consisted of atrophy and droplet formation of the middle and marginal zones. In one area, an atrophied tectorial membrane was lifted up by a mass on the limbus. The saccular wall in the left temporal bone was ruptured. There was no pathology in the vascular system in the labyrinths except for moderate degeneration of sensory epithelium. The pathogenesis of sudden deafness was discussed in the light of the present findings. Alteration of the tectorial membrane seemed to be the main factor as a possible cause of sudden deafness. Histopathological findings were reviewed from the literature.
mesh_terms: D000328:Adult; D000368:Aged; D001299:Audiometry; D003051:Cochlea / Q000473:pathology; D003638:Deafness / Q000473:pathology*; D007758:Ear, Inner / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009925:Organ of Corti / Q000473:pathology; D012444:Saccule and Utricle / Q000473:pathology; D013701:Temporal Bone / Q000473:pathology