Comparison of the visco-elastic properties of the tail artery in spontaneously hypertensive and normotensive rats.
The quasistatic and dynamic elastic behaviour of the tail artery of male normotensive (NCR) and spontaneously hypertensive (SHR) rats was determined in vitro. The tone of the smooth muscle was enhanced by norepinephrine and diminished by papaverine. The circumferential wall stress was changed by varying the transmural pressure level. The experimental procedure was the same as that used in a previous investigation (Bauer and Pasch, 1971). The circumferential (tangential) elastic wall modulus Et was calculated from the mean internal and external radii determined at each pressure level and from dynamic pressure-volume recordings in the frequency range between 0.03 and 20 HZ. The calculation was based on a formula valid for thick-walled, longitudinally constrained vessels.
D000818:Animals; D001158:Arteries / Q000503:physiopathology*; D004548:Elasticity; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D009130:Muscle, Smooth / Q000503:physiopathology; D009638:Norepinephrine / Q000494:pharmacology; D010208:Papaverine / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013623:Tail / Q000098:blood supply
D010208:Papaverine; D009638:Norepinephrine