Lymphocyte response to phytomitogens in iron deficiency.
The lymphocytes of iron-deficient anemic and nonanemic patients have a decreased response to phytomitogens. Treatment of these patients with iron is followed by restoration of the lymphocyte response to normal. These findings indicate an important nonhemoglobin function of iron. Iron deficiency may be a factor in the production or potentiation of immune deficiency.
D000328:Adult; D000745:Anemia, Hemolytic, Congenital / Q000276:immunology; D000747:Anemia, Hypochromic / Q000188:drug therapy / Q000276:immunology*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007501:Iron / Q000627:therapeutic use; D000090463:Iron Deficiencies; D037102:Lectins / Q000494:pharmacology*; D008213:Lymphocyte Activation; D008297:Male; D008934:Mitogens / Q000494:pharmacology; D011087:Polycythemia Vera / Q000276:immunology
D037102:Lectins; D008934:Mitogens; D007501:Iron