Evoked potential alterations in methylmercury chloride toxicity.
The present study was designed to assess the sensitivity of evoked potential techniques to detect alterations in offspring exposed to methylmercury chloride (MMC) at different developmental periods. Recordings were obtained from the visual cortex (VEP) and lateral geniculate (LGP) in 30-day old offspring. Results revealed decreased VEP latencies for peaks N1, P1, and P2 in offspring from mothers exposed either during gestation, or nursing and in offspring exposed directly to MMC for 9 days after weaning. Although not significant, a similar trend was observed in the LPG. It is suggested that the decreased latencies may be a result of compressed brain development.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004327:Drinking Behavior / Q000187:drug effects; D005071:Evoked Potentials / Q000187:drug effects*; D005260:Female; D005829:Geniculate Bodies / Q000187:drug effects; D008767:Methylmercury Compounds / Q000494:pharmacology*; D051381:Rats; D014793:Visual Cortex / Q000187:drug effects
D008767:Methylmercury Compounds