title: Use of hemiacidrin in management of infection stones.
abstract: Unless all fragments are removed at the time of surgery for struvite stones a high incidence of recurrent infection and stone formation is likely. To reduce the recurrence rate of such stones the renal pelvis is irrigated postoperatively with 10 per cent hemiacidrin solution for at least 48 hours or until all fragments have been dissolved. We have managed successfully 35 patients (36 kidneys) without enxountering any complications. Included in our most recent series are 2 patients with solitary kidneys who had successful dissolution of stone fragments. Absolute contraindications to the use of hemiacidrin are infected urine, fever or flank discomfort. Although we have found hemiacidrin dissolution of renal stones to be safe and effective it is essential that the clinician be aware of the proper technique and its possible complications.
mesh_terms: D000368:Aged; D002951:Citrates / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D008274:Magnesium; D008297:Male; D008875:Middle Aged; D009393:Nephritis / Q000150:complications*; D010592:Pharmaceutic Aids / Q000627:therapeutic use*; D010710:Phosphates; D000644:Quaternary Ammonium Compounds; D012008:Recurrence; D007507:Therapeutic Irrigation
chemical_list: D002951:Citrates; D010592:Pharmaceutic Aids; D010710:Phosphates; D000644:Quaternary Ammonium Compounds; D008274:Magnesium