title: [Changes in blood sugar and ammonium levels after ligation of the afferent hepatic vessels].
abstract: Blood sugar and ammonia levels were studied after ligation of the afferent vessels of the liver. Isolated liver anoxia and isolated splanchnic stagnation were produced by means of a side-to-side porto-caval anastomosis in dogs. Isolated liver ischaemia for 45 minutes did not lead to a typical change in blood sugar and ammonia levels. In splanchnic stagnation with intact hepatic circulation, hyperglycaemia and a high blood ammonia level appeared in the portal venous blood. Thus, in the first 45 minutes afferent hepatic vessels are primarily due to splanchnic stagnation and not to hepatic ischaemia. When splanchnic stagnation and hepatic ischaemia occur simulatneously, the enhanced production of metabolites and the lack of compensation lead to a rapid lethal outcome.
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D004285:Dogs; D005260:Female; D006501:Hepatic Encephalopathy / Q000097:blood; D008026:Ligation; D008099:Liver / Q000098:blood supply* / Q000378:metabolism; D008297:Male; D010101:Oxygen Consumption; D011167:Portacaval Shunt, Surgical; D000644:Quaternary Ammonium Compounds / Q000097:blood*; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D000644:Quaternary Ammonium Compounds
vernacular_title: Uber die änderungen des blutzucker- und blutammoniakspiegels nach abklemmung der afferenten lebergefässe