title: Chronic proximal muscular weakness in alcoholics.
abstract: In spite of the fact that peripheral neuropathy is very common in alcoholics, the chronic proximal muscular weakness and wasting found in alcoholics have been ascribed to myopathy. A clinical, biochemical, and histological study of 13 patients provided evidence for neuropathy. Enzymic histochemistry of muscle demonstrated selective type 2 neurogenic atrophy with evidence of reinnervation.
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications* / Q000473:pathology; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons; D009132:Muscles / Q000473:pathology; D009133:Muscular Atrophy / Q000209:etiology* / Q000473:pathology; D009468:Neuromuscular Diseases / Q000150:complications