[Quantitative evaluation of the dose-response relationship after intramuscular administration of testosterone and its esters].
Experiments were conducted on rats. A study was made of the reaction of target organs to the intramuscular injection of androgenic preparations--testosterone and its esters (acetate, propionate, phenylpropionate, isocapronate, enantate and caprinate) comparison with anabolic methylandrostendiol. An equation is presented for mathematical description of the dependence of the androgenic effect on the dose of the praparations injected, used in a wide range of doses. The equation coefficients proved to have a definite physiological sense.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D007273:Injections, Intramuscular; D008297:Male; D008695:Methandriol / Q000008:administration & dosage / Q000494:pharmacology; D009929:Organ Size / Q000187:drug effects; D011467:Prostate / Q000187:drug effects; D051381:Rats; D012669:Seminal Vesicles / Q000187:drug effects; D013739:Testosterone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology
D013739:Testosterone; D008695:Methandriol
Kolichestvennaia otsenka zavisimosti doza-effekt pri vnutrimyshechnom vvedenii testosterona i ego efirov.