Limulus test, parenteral drugs and biological products: an approach.
The Authors report the results concerning the control of presence of bacterial endotoxins in parenteral drugs, blood products and immunological materials, by means of Limulus amebocyte lysate test. All the data suggest that Limulus assay is a simple, rapid, specific and sensitive test for endotoxin detection, mostly when it is correctly performed.
D000907:Antibodies, Bacterial / Q000302:isolation & purification; D000917:Antibody Formation; D001181:Arthropods / Q000276:immunology*; D001688:Biological Products / Q000032:analysis*; D004340:Drug Contamination / Q000517:prevention & control*; D004731:Endotoxins / Q000302:isolation & purification*; D006737:Horseshoe Crabs / Q000276:immunology*; D007267:Injections
D000907:Antibodies, Bacterial; D001688:Biological Products; D004731:Endotoxins