[Shifts in several aspects of phospholipid metabolism in the brains of white rats with radiation sickness].
Sublethal (400) and lethal (1600) doses of roentgen decrease the level of neutral phospholipids of rat brain and increase that of acid phospholipids. With the development of radiation disease the content of free glycerine and glycerophosphate increases and the glycerokinase and glycolytic pathways of glycerophosphate biosynthesis are activated together with the intensification of the direct and reverse reactions catalyzed by glycerophosphate dehydrogenase. The permeability of the artificial bimolecular phospholipid membranes prepared from rat brain phospholipid extracts is significantly increased at the end of the radiation.
D000818:Animals; D001921:Brain / Q000201:enzymology / Q000378:metabolism / Q000528:radiation effects*; D005993:Glycerolphosphate Dehydrogenase / Q000378:metabolism; D008297:Male; D010743:Phospholipids / Q000378:metabolism / Q000528:radiation effects*; D011833:Radiation Injuries, Experimental / Q000201:enzymology / Q000378:metabolism*; D051381:Rats; D013997:Time Factors; D014965:X-Rays
D010743:Phospholipids; D005993:Glycerolphosphate Dehydrogenase
Sdvigi nekotorykh storon fosfolipidnogo obmena v golovnom mozgu belykh krys pri luchevoĭ bolezni.