[RNA synthesis in the circular nucleoli of hepatocytes].
By analysis of serial sections it has been revealed that the so-called ring-like nucleoli of hepatocytes consist of a cavity with an amorphous contents surrounded by fibrillar and granular material. Such nucleoli are sometimes encountered in normal animals; the number of ring-like nucleoli increases considerably in chronic pathological process caused by repeated CCl4 injections. The capacity of RNA synthesis in the ring-like nucleoli was revealed by means of electron-microscopic autoradiography.
D000818:Animals; D001345:Autoradiography; D002252:Carbon Tetrachloride Poisoning / Q000378:metabolism* / Q000473:pathology; D002466:Cell Nucleolus / Q000378:metabolism* / Q000648:ultrastructure; D056486:Chemical and Drug Induced Liver Injury / Q000378:metabolism* / Q000473:pathology; D008099:Liver / Q000378:metabolism / Q000648:ultrastructure*; D051379:Mice; D008854:Microscopy, Electron; D012313:RNA / Q000096:biosynthesis*
D012313:RNA
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