title: [Morphology of experimental argyrosis in kidneys].
abstract: Prolonged per os administration of silver nitrate solution in rats will result in the development of experimental argyrosis with particles of silver in the kidneys being deposited mainly in the glomerular basal membranes. Apart from that, particles of silver in the glomeruli were also found in the mesangioma and, in minor quantities, in podocytes and endothelial cells. Outside the glomerular structures, silver was found deposited in tubular basal membranes, in the proximal tubule epithelium and minute vessel wals. -- A discussion is presented of the possible mechanisms involved in the development of such deposits, as well as of the relationship between intravital silver depositing and some of the tissues affinity to silver, a property taken advantage of in histological methods.
mesh_terms: D000818:Animals; D001129:Argyria / Q000378:metabolism / Q000473:pathology*; D004195:Disease Models, Animal; D007674:Kidney Diseases / Q000378:metabolism / Q000473:pathology*; D007678:Kidney Glomerulus / Q000378:metabolism / Q000473:pathology; D008854:Microscopy, Electron; D051381:Rats; D012834:Silver / Q000378:metabolism
chemical_list: D012834:Silver
vernacular_title: Morfológia experimentálnej argyrózy v oblickách.