The investigation of quindoxin photosensitivity.
Quindoxin (quinoxaline di-N-oxide) is a photosensitizer capable of producing photocontact dermatitis. The study of a group of seven affected subjects has provided evidence of persistent light reaction and "photoallergy", most probably to the parent substance and not to any photoproduct or contaminant. Clinical and photobiological similarities to the photosensitivity dermatitis and actinic reticuloid syndrome were demonstrated.
D000287:Administration, Topical; D000383:Agriculture; D000485:Allergens; D005260:Female; D006801:Humans; D008213:Lymphocyte Activation / Q000528:radiation effects; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D010787:Photosensitivity Disorders / Q000209:etiology*; D011810:Quinoxalines / Q000032:analysis / Q000276:immunology* / Q000528:radiation effects; D013997:Time Factors; D014466:Ultraviolet Rays
D000485:Allergens; D011810:Quinoxalines