Protein status in bilharziasis in Egyptian children.
Fifty-nine bilharzial subjects aged 9-12 years and 18 parallel controls were investigated for total serum proteins, total liver proteins and total urinary proteins. Simple agar gel and immunoelectrophoretic studies were also carried out. The results revealed a highly significant decrease in serum total proteins in mixed infection. A very highly significant increase was demonstrated for serum alpha, globulin. The gamma globulin fraction and the total globulin moiety were very highly significantly raised. The albumin globulin ratio was considerably decreased in mansoniasis. Serum immunoelectrophoresis illustrated a decreased density of haptoglobulin, hemopexin and transferrin arcs, as well as a considerable increase in IgA, IgM and IgG in most of the cases. Urinary protein values were very highly significantly elevated in hematobiasis and mixed infection. A slight increase for alpha1, alpha2 and beta-globulins was found in some cases. Liver proteins were very highly significantly decreased in mansoniasis and mixed infection. The results are discussed and analysed.
D001798:Blood Proteins / Q000032:analysis*; D002648:Child; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D008099:Liver / Q000032:analysis / Q000503:physiopathology; D011506:Proteins / Q000032:analysis; D011507:Proteinuria / Q000209:etiology*; D012552:Schistosomiasis / Q000175:diagnosis* / Q000503:physiopathology
D001798:Blood Proteins; D011506:Proteins