["Superficial spreading melanoma" within a psoriasis focus as a delayed sequela following arsenic therapy for psoriasis].
After a longlasting psoriasis (25-30 years) and after an arsenotherapy of psoriasis per os fifteen years ago an arsenic-caused injury occured with formation of a melanoma within the surrounding psoriasis. In examinating comparable Moselle vine dressers with late arsenic-caused injuries during the years 1972-1975, altogether 1600 examinations, precancerosis, basaliomas, morbus-Bowen, spinaliomas, and transitional epithelium carcinomas have been found and have been histologically confirmed. No melano malignom has been found. Al in eleven other cases of vine dressers with arsenic-caused late injuries showing keratosis, precancerosis, and basaliomas together with a long-lasting psoriasis vulgaris no melano malignom has been found.
D000328:Adult; D001151:Arsenic / Q000009:adverse effects* / Q000627:therapeutic use; D001913:Bowen's Disease / Q000139:chemically induced*; D002280:Basal Cell Carcinoma / Q000139:chemically induced*; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced*; D005260:Female; D006801:Humans; D011565:Psoriasis / Q000150:complications / Q000188:drug therapy*; D012878:Skin Neoplasms / Q000139:chemically induced*
D001151:Arsenic
"Superficial spreading melanoma" in Psoriasis-Herd bei Arsenspätfolgeschaden nach Arsen-Psoriasis-Therapie