[Characteristics of the label incorporation from 2-14C-glycine into the tissues of animals of differing ages].
Peculiarities of 14C incorporation into proteins and lipids of the liver, kidneys, heart and muscles tissues as well as blood serum and protein-free filtrates of tissues were studied in young and old rats in different periods after glycin-2-14C administration. It is shown that incorporation of 14C into the tissue of young rats as well as its evacuation from the organism is more rapid. At the same time a change in dynamics of the precursors content in individual organs of animals of both age groups is of indirected character. A conclusion is drawn that acceleration of the radioactive label evacuation due to a more rapid exchange--ability of proteins in the young animals tissues might be one of the reasons of discrepancy between a higher level of radioactivity in the tissues of old rats and a total decrease in the intensity of metabolism during ontogenesis.
D000367:Age Factors; D000818:Animals; D001769:Blood / Q000378:metabolism; D002244:Carbon / Q000378:metabolism*; D002250:Carbon Radioisotopes; D005998:Glycine / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D051381:Rats; D013997:Time Factors
D002250:Carbon Radioisotopes; D011506:Proteins; D002244:Carbon; D005998:Glycine
Osoblyvosti vkliuchennia mitky z 2-14C-hlitsynu v tkanyny tvaryn riznoho viku