[Effect of cold exposure on synthesis of cerebral dopamine (author's transl)].
The synthesis of dopamine (DA) has been studied in the striatum and cortex of rats exposed to a temperature of 40C for 2.5 or 24 h. The synthesis rate has been estimated 30 mn after an i.v. injection of 3H tyrosine (TY), by the evaluation of the ratio: 3H-DA specific activity 3H-TY specific activity. Cold exposure modified DA synthesis differently in the two brain areas. In the striatum, DA synthesis was multiplied by a factor of 1.5 after 2.5 h of cold exposure and returned to normal value after 24 h. In the cortex, cold exposure did not significantly change DA synthesis (at any of the two times studied).
D000818:Animals; D002540:Cerebral Cortex / Q000378:metabolism*; D003080:Cold Temperature; D003342:Corpus Striatum / Q000378:metabolism*; D004298:Dopamine / Q000096:biosynthesis*; D007700:Kinetics; D008297:Male; D051381:Rats; D014443:Tyrosine / Q000378:metabolism
D014443:Tyrosine; D004298:Dopamine
Influence de l'exposition au froid sur la synthèse de la dopamine cérébrale