[Success in the induction of labor by peroral administration of Prostin E 2 in relation to Sandopart].
The results of the use of Prostin E2 in the induction of labour in 46 pregnant women were compared with the results obtained by Sandopart in 40 pregnant women. To avoid the effect of amnyotomy, both groups were examined without carrying out routine amnyotomy. The results have shown that a significantly better efficacy in the induction of labour was obtained with Prostin E2. This efficacy was very good regardless of the cervix assessed by the Bishop score, while the reaction of the uterus to Sandopart proved the poorer the lower the Bishop score. The mother's condition, established by clinical and laboratory examinations, did not change significantly in the course or after the administration of Prostin E2. Nor did the condition of infants, assessed by the Apgar score, differ from the condition of children from the group of labour induced by Sandopart. This shows that the induction by Prostin E2 is just as efficacious as the induction by Sandopart if the cervix is mature; if the cervix is not mature, the induction by Prostin E2 is even more efficacious.
D000284:Administration, Oral; D005260:Female; D006801:Humans; D007745:Labor Onset / Q000187:drug effects*; D007751:Labor, Induced; D007743:Labor, Obstetric / Q000187:drug effects*; D010121:Oxytocin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D011225:Pre-Eclampsia; D011247:Pregnancy; D011273:Pregnancy, Prolonged / Q000187:drug effects; D011458:Prostaglandins E / Q000008:administration & dosage / Q000494:pharmacology*
D011458:Prostaglandins E; C004748:deaminooxytocin; D010121:Oxytocin
Uspjesnost indukcije porodaja peroralnom primjenom Prostina E2 odnosno Sandoparta.