[Humoral factors in the regulation of the natriuretic function of the kidneys].
Acute experiments were conducted on dogs. Intravenous injection of adrenalin (1--2 Mg/kg/min) caused an increase in the blood renin content and a reduction of the renal excretion of sodium, potassium and water. Noradrenaline (1--2 Mg/kg/min) produced the contrary changes in the renin secretion and diuresis, this being associated with a different activity of catecholamines in respect to tha alpha- and beta-adrenoreceptors. It is supposed that in acute hemodynamic shifts renin could play the role of intrarenal mediator of the natriuretic reaction.
D000818:Animals; D001834:Body Water / Q000378:metabolism; D004285:Dogs; D004837:Epinephrine / Q000494:pharmacology / Q000502:physiology*; D006439:Hemodynamics / Q000187:drug effects; D007668:Kidney / Q000502:physiology*; D009318:Natriuresis; D009638:Norepinephrine / Q000494:pharmacology / Q000502:physiology; D011188:Potassium / Q000652:urine; D012083:Renin / Q000097:blood; D012964:Sodium / Q000652:urine
D012964:Sodium; D012083:Renin; D011188:Potassium; D009638:Norepinephrine; D004837:Epinephrine
Gumoral'nye faktory v reguliatsii natriĭureticheskoĭ funktsii pochek