[Change in the activity and lactate dehydrogenase isoenzyme spectrum in rat lungs, liver and kidney cortex under the effect of hydrocortisone, insulin and hypoxia].
Pretreatment of rats with hydrocortisone or protamin-Zn-insulin within 4 days altered in subsequent acute hypoxia (3 hrs, "height" 10 000 m) the isoenzyme spectrum of LDH in lungs, liver tissue and kidney cortex. The differences in alterations in the activity and content of LDH isoenzymes were observed in tissues with various types of metabolism.
D000208:Acute Disease; D000818:Animals; D003720:Densitometry; D004591:Electrophoresis, Polyacrylamide Gel; D006854:Hydrocortisone / Q000494:pharmacology*; D000860:Hypoxia / Q000201:enzymology*; D049528:Insulin, Long-Acting / Q000494:pharmacology*; D007527:Isoenzymes; D007672:Kidney Cortex / Q000032:analysis / Q000201:enzymology*; D007770:L-Lactate Dehydrogenase / Q000032:analysis / Q000378:metabolism*; D008099:Liver / Q000032:analysis / Q000201:enzymology*; D008168:Lung / Q000032:analysis / Q000201:enzymology*; D051381:Rats
D049528:Insulin, Long-Acting; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D006854:Hydrocortisone
Izmenenie aktivnosti i izofermentnogo spektra laktatdegidrogenazy v legkikh, pecheni i korkovom sloe pochki krysy pri deístvii gidrokortizona, insulina i gipoksii