[Effects of catecholaminergic substances on the circular reaction caused by stimulation of the caudate nucleus].
The influence of stimulators (L-DOPA and apomorphine) and of inhibitors (chlorpromazine and haloperidol) of the dopaminergic systems on the circular reaction arising during high-frequency (30 puls/sec) stimulation of the caudate nucleus was studied in chronic experiments with freely moving cats carrying  preliminarily implanted electrodes. L-DOPA and apomorphine inhibited, while chlorpromazine, on the contrary, facilitated the development of a contralateral circular reaction. L-DOPA and chlorpromazine modified in a more pronounced fashion the circular reaction than did apomorphine and haloperidol. In the mechanisms of the circular reaction, apart from the dopaminergic component, the participation of noradrenergic systems is suggested.
D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D002415:Cats; D002421:Caudate Nucleus / Q000187:drug effects* / Q000502:physiology; D002746:Chlorpromazine / Q000494:pharmacology; D003864:Depression, Chemical; D004558:Electric Stimulation; D006220:Haloperidol / Q000494:pharmacology; D007980:Levodopa / Q000494:pharmacology*; D008124:Locomotion / Q000187:drug effects*; D009068:Movement / Q000187:drug effects*; D013268:Stimulation, Chemical
D007980:Levodopa; D006220:Haloperidol; D001058:Apomorphine; D002746:Chlorpromazine
Vliianie katekholaminergicheskikh veshchestv na tsirkuliarnuiu readtsiiu, vyzvannuiu razdrazheniem khvostatogo iadra.