The chemistry of schistosomicides.
The chemistry of the different compounds applied in the field of schistosomicides has been reviewed in detail. On the basis of their chemical constitution, these compounds have been classified into: organotrivalent antimonials; Xanthones and related compounds "xanthones, chromones and mirasans"; Nitroheterocyclic compounds "nitroquinolines, nitrofurans and nitrothiazoles"; Miscellaneous compounds "phenoxy compounds, piperazines, naphthylazo compounds, phosphorous compounds, carbanilides, rosanilines, salicyclic acid derivatives and natural products". On consideration of biochemical and pharmacological investigations, studies concerned with mechanism of action, metabolic changes and comparative toxic effects of some groups of these compounds are reported. Investigations on the relation between constitution and action among variety of these compounds are included.
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D006801:Humans; D012556:Schistosomicides; D013329:Structure-Activity Relationship
D012556:Schistosomicides