[Effect of duodenal contents of patients with pancreatitis following its introduction into the duodenum of healthy rats].
The authors examined 18 rats--6 controls and 12 experimental. After duodenostomy by means of a puncure of the duodenal wall duodenal content from healthy persons was administered in the duodenum of control rats. In the experimental group of animals duodenal content form patients with pancreatitis was administered. Duodenum, pancrea, liver and kidneys were examined histomorphologicaly. The obtained results showed that there were no substantial deviations from the norm in the histomorphological picture of the examined organs after administration of duodenal content. In the organs of the experimental group these changes could be characterized as acute necrotic pancreatitis, acute duodenitis, acute finely dotted dystrophy of liver and slightly, manifested acute renal insufficiency. the authors suggested the occurrence of some toxic substances in the duodenal content in patients with acute pancreatitis.
D058186:Acute Kidney Injury / Q000209:etiology; D000818:Animals; D004386:Duodenum / Q000032:analysis* / Q000473:pathology; D004751:Enteritis / Q000209:etiology; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000209:etiology; D008297:Male; D010179:Pancreas / Q000473:pathology; D010195:Pancreatitis / Q000378:metabolism*; D051381:Rats; D014118:Toxins, Biological / Q000032:analysis*
D014118:Toxins, Biological
Deĭstvie na duodenalnoto sudurzhimo ot pankreasno bolni pri vlivaneto mu v dvanadesetoprustnoto chervo na zdravi plukhove