[Inhibiting effect of cholera vibrio neuraminidase in Rauscher mouse leukemia].
A study was made of the inhibitory effect of neuraminidase of cholera vibrio in mouse Rauscher leukemia. It was shown that the processing of cells of the spleen of mice suffering from leukemia with neuraminidase (in a dose of 50 units/ml and more) significantly inhibited the capacity of these cells to induce leukemia in their injection to BALB/c mice. In the mentioned concentration neuraminidase injected repeatedly parenterally produced no therapeutic effect in Rauscher leukemia.
D000818:Animals; D000970:Antineoplastic Agents; D007942:Leukemia, Experimental / Q000188:drug therapy*; D051379:Mice; D008807:Mice, Inbred BALB C; D009439:Neuraminidase / Q000627:therapeutic use*; D011925:Rauscher Virus; D014734:Vibrio cholerae / Q000201:enzymology*
D000970:Antineoplastic Agents; D009439:Neuraminidase
Ingibiruiushchee deĭstvie neĭraminidazy kholernykh vibrionov pri leĭkoze mysheĭ Raushera