title: The results of 100 small tissue biopsies of testis in male infertile patients.
abstract: The value of testicular biopsy in male infertility has recently been emphasized by Meinhard, McRae and Chisholm (1973), and the present authors agree with them that a biopsy is essential for the following reasons: (1) to establish a firm diagnosis; (2) to rationalize therapy on the basis of histological findings; (3) new developments in drug therapy and electronmicroscopic techniques will help to clarify many areas of doubt and uncertainty in this difficult field; (4) the diagnosis of 'sloughing' by itself may mask changes in germinal cell development which may be amenable to hormone therapy.
mesh_terms: D000728:Androgens / Q000627:therapeutic use; D001706:Biopsy; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D008297:Male; D013091:Spermatogenesis; D013737:Testis / Q000033:anatomy & histology / Q000473:pathology*; D014646:Varicocele / Q000150:complications
chemical_list: D000728:Androgens