[Changes in the hemodynamic indices of the pulmonary circulation and in the functional state of the right ventricular myocardium in stage II hypertension under certain types of hypotensive therapy].
The author observed 76 patients with Stage II essential hypertension undergoing combined therapy with Rauwolfia serpentaria, Isobarine and Hypothiazid, 37 patients treated with Dopegit, and 44--with Obsidan. The examined patients demonstrated pulmonary arterial hypertension or a tendency towards its development, an increasing lung-ear time interval, and a reduced functional capacity of the right ventricular myocardium. A direct correlation was established between the level of blood pressure in the general circulation and the pressure in the pulmonary artery and the degree of blood flow deceleration in the lung-ear interval. Combined therapy results in a reduction of the elevated blood pressure not only in the general, but also in the pulmonary circulation.
D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D006321:Heart / Q000187:drug effects*; D006334:Heart Function Tests; D006339:Heart Rate / Q000187:drug effects; D006352:Heart Ventricles / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011652:Pulmonary Circulation / Q000187:drug effects*
D000959:Antihypertensive Agents
Izmeneniia pokazateleĭ gemodinamiki v malom kruge krovoobrashcheniia i funktsional'nogo sostoianiia miokarda pravogo zheludochka serdtsa u bol'nykh gipertonicheskoĭ bolezn'iu II stadii pri nekotorykh vidakh gipotenzivnoĭ terapii