Metabolism of individual fatty acids in heart muscle.
We have studied the incorporation of various long chain fatty acids into tissue lipids using various heart preparations. We found that individual fatty acids are incorporated into various lipid fractions at unequal rates. In particular, erucic acid was shown to be a poor acyl donor for various acylation reactions. Labeling of triacylglycerol by exogenous fatty acid was found to be extremely rapid in the perfused rat heart and in the in vivo heart.
D000818:Animals; D004883:Erucic Acids / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000378:metabolism*; D007700:Kinetics; D008055:Lipids / Q000096:biosynthesis*; D009206:Myocardium / Q000378:metabolism*; D009829:Oleic Acids / Q000378:metabolism; D010169:Palmitic Acids / Q000378:metabolism; D010477:Perfusion; D010743:Phospholipids / Q000096:biosynthesis; D051381:Rats
D004883:Erucic Acids; D005230:Fatty Acids, Nonesterified; D008055:Lipids; D009829:Oleic Acids; D010169:Palmitic Acids; D010743:Phospholipids