title: [A chordoma of sacrococcygeal region as a cause of nephrotic syndrome (author's transl)].
abstract: A case of nephrotic syndrome connected with a chordoma of the sacrococcygeal region in a man aged 27 is described. Biopsy of the kidney revealed a diffuse membranous glomerulonephritis. Immunofluoresecenc showed deposits of IgG immunoglobulin on the basal membrane of glomeruli. In the patient's serum autoantibodies against chordoma cells were found. Those were also IgG globulins. To our knowledge such a relation of chordoma and nephrotic syndrome has not been described yet.
mesh_terms: D000328:Adult; D000912:Antibodies, Neoplasm / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis; D001706:Biopsy; D002817:Chordoma / Q000150:complications*; D003165:Complement System Proteins / Q000032:analysis; D005921:Glomerulonephritis / Q000150:complications / Q000473:pathology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007668:Kidney / Q000473:pathology; D008297:Male; D009404:Nephrotic Syndrome / Q000209:etiology* / Q000473:pathology; D012445:Sacrococcygeal Region
chemical_list: D000912:Antibodies, Neoplasm; D001323:Autoantibodies; D007074:Immunoglobulin G; D003165:Complement System Proteins
vernacular_title: Nephrotisches Syndrom, verursacht durch ein lumbosakrales Chordom