title: Some experience of the use of etomidate in children.
abstract: Etomidate 0.2 mg/kg was used as an intravenous hypnotic to induce anesthesia in 198 children. If proved to be a safe and effective agent, with no appreciable side-effects on the cardiovascular or respiratory systems. The main problems in use were a high incidence (27%) of pain after injection, and a 10% incidence of significant myoclonia. In addition, 0.2 mg/kg was assessed as an inadequate induction dose of etomidate in unpremedicated children.
mesh_terms: D000293:Adolescent; D001794:Blood Pressure / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005045:Etomidate / Q000009:adverse effects; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006993:Hypnotics and Sedatives; D007093:Imidazoles; D007223:Infant; D007231:Infant, Newborn; D009207:Myoclonus / Q000139:chemically induced; D010146:Pain / Q000139:chemically induced
chemical_list: D006993:Hypnotics and Sedatives; D007093:Imidazoles; D005045:Etomidate