[Effect of acetycholine on the Ca2+ transport system in sarcoplasmic reticulum of frog skeletal muscle].
In fragments of sarcoplasmic reticulum of the frog abdominal straight muscle the functional properties of Ca2+ transport and effect of acetycholine on those properties were studied. The rate of Ca2+ accumulation was decreased due to stimulation by acetylcholine the Ca2+ out-flow from the reticular vesicles. The ratio Ca2+/ATP decreased and the Ca2+-ATPase activity was increased. The Ki vlaue for the inhibition by acetylcholine of Ca2+ absorption was 60micronM. Effect of acetylcholine on the Ca2+ transport depended on the temperature of medium.
D000042:Absorption; D000109:Acetylcholine / Q000494:pharmacology*; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001001:Anura; D001693:Biological Transport, Active / Q000187:drug effects; D002118:Calcium / Q000378:metabolism*; D006868:Hydrolysis; D009132:Muscles / Q000166:cytology; D011898:Ranidae; D012519:Sarcoplasmic Reticulum / Q000378:metabolism*; D013268:Stimulation, Chemical
D000255:Adenosine Triphosphate; D000109:Acetylcholine; D002118:Calcium
Vliianie atsetilkholina na sistemu transporta Ca2+ sarkoplazmaticheskogo retikuluma skeletnoĭ myshtsy liagushki