[Study of the mechanism of erythropoietin effect on energy metabolism in the bone marrow].
In extracts of rabbit bone marrow cells was studied effect of erythropoietine on the activity of some enzymes (hexokinase, phosphoglucomutase, phosphohexoisomerase, lactate dehydrogenase, glucoso-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and NADP-reductase). The NADP-reductase activity was increased under the effect of erythropoietine; the activities of other enzymes studied was not altered.
D000818:Animals; D001853:Bone Marrow / Q000201:enzymology / Q000378:metabolism*; D001854:Bone Marrow Cells; D004734:Energy Metabolism; D004921:Erythropoietin / Q000502:physiology*; D005956:Glucose-6-Phosphate Isomerase / Q000378:metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006593:Hexokinase / Q000378:metabolism; D066298:In Vitro Techniques; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism; D010101:Oxygen Consumption; D010733:Phosphoglucomutase / Q000378:metabolism; D010734:Phosphogluconate Dehydrogenase / Q000378:metabolism; D011817:Rabbits; D051381:Rats
D004921:Erythropoietin; D007770:L-Lactate Dehydrogenase; D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D009247:NADH, NADPH Oxidoreductases; D006593:Hexokinase; D005956:Glucose-6-Phosphate Isomerase; D010733:Phosphoglucomutase
Izuchenie mekhanizma deistviia eritropoetina na energeticheskiĭ obmen kostnogo mozga