Panel V: Acceleration of collaterals due to physical activity--dogma or fast. A misguided goal or unrealized objective?--introduction.
The hypothesis drawn from Eckstein's study of dogs [5] suggests that collateral circulation (measured retrograde coronary collateral flow) could be enhanced in man provided that the coronary arteries were partially obstructed before training. The currently available data on the effects of exercise training on arteriosclerotic heart disease subjects with significant, but not complete, obstruction, and without collateral vessels before training, indicate that visible coronary collateral vessels do not develop unless further coronary obstruction progresses to complete or near complete occlusion. Although the above hypothesis is not supported by the angiographic studies to date, final judgment should be held in abeyance until data are presented on the collateral flow and regional myocardial perfusion in exercise-trained human subjects with arteriosclerotic heart disease.
D000818:Animals; D003097:Collateral Circulation; D003326:Coronary Circulation; D003327:Coronary Disease / Q000534:rehabilitation*; D003331:Coronary Vessels / Q000473:pathology*; D004285:Dogs; D006801:Humans; D005082:Physical Exertion