[Calcium in the prevention of stress ulcer in the rat].
Calcium gluconate, carbonate, and lactate are potent antiulcerogenic agents when administered intragastrically at pH 6.3 by sustained infusion (45 mg/kg/8 h). In intact rats, by radioimmunologically measurable serum, gastrin and calcitonin are inversely correlated, whereas gastrin and ulcer index tend to correlate directly. The findings imply a key role for thyroid-releasable endogenous calcitonin in this disorder.
D000818:Animals; D002118:Calcium / Q000627:therapeutic use*; D002119:Calcium Carbonate / Q000627:therapeutic use; D002122:Calcium Chloride / Q000627:therapeutic use; D008297:Male; D010437:Peptic Ulcer / Q000209:etiology / Q000517:prevention & control*; D051381:Rats; D013312:Stress, Physiological / Q000150:complications*
D002119:Calcium Carbonate; D002122:Calcium Chloride; D002118:Calcium
Calcium in der Prophylaxe des Stressulcus der Ratte.