title: Effect of potato protease inhibitor on the clotting system and fibrinolysis in the dog.
abstract: The potato inhibitor of proteolytic enzymes was found to inhibit the plasma clotting and fibrinolytic systems in the dog. The anticoagulative action of potato inhibitor consists in a prolongation of clotting time, inhibition of thromboplastin generation, reduction of prothrombin consumption and of the retractility of the blood clot. The potato inhibitor prolongs the euglobulin fibrinolysis time and causes a rise in the plasma antiplasmin level.
mesh_terms: D000818:Animals; D001777:Blood Coagulation; D004285:Dogs; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005342:Fibrinolysis; D010944:Plants; D011480:Protease Inhibitors
chemical_list: D004791:Enzyme Inhibitors; D011480:Protease Inhibitors