A trial of Fortagesic and Paramol 118 in osteoarthritis.
Fortagesic was compared with Paramol 118 in a fourteen day single-blind crossover study in patients with moderate pain due to osteoarthritis. Both preparations were shown to be similarly effective. More side-effects were seen with Paramol 118 than with Fortagesic and more patients preferred Fortagesic. These differences were not statistically significant, but it is concluded that Fortagesic is a useful effective analgesic for standard use in moderate pain.
D000082:Acetaminophen / Q000009:adverse effects / Q000627:therapeutic use*; D003061:Codeine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D004338:Drug Combinations; D006801:Humans; D010003:Osteoarthritis / Q000188:drug therapy*; D010423:Pentazocine / Q000009:adverse effects / Q000627:therapeutic use*
D004338:Drug Combinations; D000082:Acetaminophen; C014481:dihydrocodeine; D010423:Pentazocine; D003061:Codeine