[Infantile nephrosis. Microcystic renal disease (author's transl)].
Two siblings, male and female with nephrotic syndrome of neonatal onset are reported. Both parents were healthy as well as another 5 year-old brother. Both died under two months. Their clinical, biochemical and immunological data are described, and the more common causes of N.S. (i.e. syphilis, toxoplasmosis, tuberculosis) ruled out. Pathology was available only from one of the cases, and the lesions were comparable to those described by finnish authors as corresponding to "congenital" N.S. This report is an additional evidence of the presence of this entity out of Finland.
D005260:Female; D005808:Genes, Recessive; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000235:genetics*; D052177:Kidney Diseases, Cystic / Q000235:genetics*; D008297:Male; D009404:Nephrotic Syndrome / Q000235:genetics*
Síndrome nefrótico del lactante. Enfermedad microquística del riñón