Myocardial fatty acid and cardiac performance.
Isoproterenol enhanced myocardial triglyceride utilization and incorporation of exogenous fatty acid into triglyceride fraction in the perfused rat heart in the presence of glucose. However, in the absence of glucose, cardiac performance was considerably aggravated by isoproterenol. This suggests that glucose might be an essential fuel in the heart stimulated by isoproterenol.
D000818:Animals; D005227:Fatty Acids / Q000378:metabolism*; D005947:Glucose / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D007545:Isoproterenol / Q000494:pharmacology; D008053:Lipid Mobilization / Q000187:drug effects; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D014280:Triglycerides / Q000378:metabolism*
D005227:Fatty Acids; D014280:Triglycerides; D005947:Glucose; D007545:Isoproterenol