title: Morphine withdrawal reactions in male and female mice.
abstract: In the present study we have used the morphine implantation method to investigate the intensity of the abstinence syndrome in both male and female Swiss Webster morphine-dependent mice. It is evident from our data that naloxone induced no significant difference in the jumping behavior of both morphine-dependent male and female mice when weight variables were controlled.
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D004343:Drug Implants; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D009020:Morphine / Q000008:administration & dosage; D009021:Morphine Dependence / Q000503:physiopathology*; D009270:Naloxone / Q000494:pharmacology; D012737:Sex Factors; D013375:Substance Withdrawal Syndrome / Q000139:chemically induced / Q000503:physiopathology*
chemical_list: D004343:Drug Implants; D009270:Naloxone; D009020:Morphine