[Calcium-dependence of bradykinin-induced contraction in the isolated longitudinal muscle of the guinea pig ileum].
The calcium-dependence of the bradykinin-induced contraction was demonstrated on the isolated logitudinal smooth muscle of the guinea-pig ileum. Using the "La-method" for measuring 45Ca entry into smooth muscle cells we were able to show, that bradykinin significantly increases the intracellular Ca-concentration. This effect of bradykinin was dose-dependent.
D000818:Animals; D001920:Bradykinin / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects*
D001920:Bradykinin; D002118:Calcium
Befunde zur Kalziumabhängigkeit der Bradykininwirkung am isolierten Längsmuskel des M-erschweinchenileums