[Evolution of pulmonary hypertension in the late period following correction of congenital heart defects].
The presented analysis is based on the data of haemodynamics studies in 62 congenital heart disease patients prior to and following surgery within 1 to 13 years (mean -- 5 years). Patent arterial duct ligation was performed in 34 cases, ventricular septal defect was closed in 28. Twenty of the patients had moderate, 42 -- high pulmonary hypertension (IIIa stage in 37 cases, IIIb stage -- in 5). Late postoperative haemodynamic studies have shown that Stage II patients demonstrated its normalization, the pulmonary artery pressure remaining above the normal level only in few cases in whom it had been 50 mm Hg and higher. In IIIa stage patients no normalization of haemodynamics is usually achieved, and in 9.1% of the cases an evolution of the total pulmonary resistance was noted. However, a distinct improvement of the haemodynamic parameters in the majority of such cases proves the efficacy of their urgical management. The persistence of high pulmonary hypertension or its progressive course in IIIb stage patients, caused by the spreading of the sclerotic process in the pulmonary vessles, indicates the inefficacy of surgery in this group of patients.
D000293:Adolescent; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000150:complications / Q000601:surgery*; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D011183:Postoperative Complications / Q000209:etiology* / Q000503:physiopathology; D011651:Pulmonary Artery / Q000503:physiopathology; D011652:Pulmonary Circulation; D014655:Vascular Resistance
Evoliutsiia legochnoĭ gipertenzii v otdalennye sroki posle kornektsii vrozhdennykh porokov serdtsa