[Variations of retinol-C14 incorporation in rats of different ages fed a vitamin A-free diet].
Two groups of Wistar strain male albino rats of different age were treated with a large dose (300 I.U.) of vitamin A-acetate, after 24 h fasting. Each rat was then administered orally a single dose of 1,25mu C retinol-C14 to determine the rate of incorporation into different tissues. At intervals of 3 h and of 3, 6, 12 days the rats were killed; liver, kidney, blood, white fat tissue, brown fat tissue were taken and dried. Radioactivity was measured. The results show that in all tissue the mean percentage of incorporation, expressed in muC/g dry tissue, is generally higher in young than in adult rats.
D000375:Aging; D000818:Animals; D008297:Male; D051381:Rats; D014018:Tissue Distribution; D014801:Vitamin A / Q000378:metabolism*; D014802:Vitamin A Deficiency / Q000378:metabolism*
D014801:Vitamin A
Variazioni dell'incorporazione del retinolo-C14 in ratti di differente età alimentati con una dieta priva di vitamina A.