title: [Role of clasmatosis of the phagocytes in immunogenesis].
abstract: With the aid of cytological and cytochemical studies it was shown that clasmatosis of phagocytes (micro- and macrophages) was primarily characteristic of active phagocytising cells, and not of dying cells as considered formerly. Experiements were conducted on guinea pigs in the course of vaccinal and infectious processes in brucellosis. As noted, clasmatosis of phagocytes known in intact animals was considerably enhanced during vaccinal and infectious processes. Pieces of cytoplasm separating from phagocytes were full of acid phosphatase, brucella antigen; fragments of macrophage cytoplasm in addition contained RNA. There are reasons to suppose that with the aid of clasmocytosis of phagocytes became intensified and the antigenic information spread rapidly in the animal organism.
mesh_terms: D000818:Animals; D000917:Antibody Formation; D002006:Brucellosis / Q000276:immunology; D003593:Cytoplasm / Q000276:immunology; D006168:Guinea Pigs; D007114:Immunization; D007136:Immunoglobulins / Q000096:biosynthesis; D008264:Macrophages / Q000276:immunology*; D010586:Phagocytes / Q000276:immunology*; D013154:Spleen / Q000276:immunology
chemical_list: D007136:Immunoglobulins
vernacular_title: O roli klazmatoza fagotsitov v immunogeneze