Molecular and cellular mechanisms of chemical carcinogenesis.
Clearly, the technics of transformation in epithelial cell cultures bring us closer to understanding chemical carcinogenesis. Also clear is the need to develop new technics to evaluate the significance of viral particles found in tumors and to answer the basic question as to whether mutation or aberrant differentiation is the mechanism of chemical carcinogenesis.
D015073:2-Acetylaminofluorene / Q000494:pharmacology; D000818:Animals; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D004261:DNA Replication / Q000187:drug effects; D008954:Models, Biological; D009374:Neoplasms, Experimental / Q000139:chemically induced*; D009858:Oncogenic Viruses; D051381:Rats
D015073:2-Acetylaminofluorene