title: Patterns of gastric electrical and motor activity in miniature pigs.
abstract: Gastric myoelectrical and mechanical activity was recorded in miniature pigs using chronically implanted electrodes and strain gauge force transducers. Semiautomated methods were devised to obtain quantitative evaluations of the electrical and mechanical parameters measured in fasted and fed animals. The patterns of gastric myoelectrical activity in pigs were, on the whole, similar to the patterns described in dogs, including regular cyclic control activity and spike response activity associated with muscle contraction. However, several points were peculiar to the species studied: conduction velocity of pacesetter potentials increased only moderately in the antrum; tachygastria never occurred in the experiments; in response to a standard meal, the frequency of pacesetter potentials gradually increased; mechanical activity proceeded at its maximal force immediately after feeding and for a long period; no evidence of 'migrating electrical complexes' was found in the stomach during fasting. The 40-min period following administration of a test meal appeared especially suitable for pharmacological or physiological experiments in which inhibitory factors are to be tested on the stomach.
mesh_terms: D000818:Animals; D002940:Circadian Rhythm; D004435:Eating; D004567:Electrodes, Implanted; D004594:Electrophysiology; D005071:Evoked Potentials; D005215:Fasting; D005260:Female; D005769:Gastrointestinal Motility; D008297:Male; D013270:Stomach / Q000502:physiology*; D013552:Swine; D013997:Time Factors