[Tissue-plasminogen-activators of maternal and fetal rat lungs after application of betamethasone or bromhexine-metabolite VIII (author's transl)].
Prenatal RDS-prevention is currently done by two substances: Corticosteroids and Bromhexine Metabolit VIII. The influence on fibrinolytic activity of these drugs in the fetal rat-lung was tested in vivo. The inhibitory effect against tissue-fibrinogen-activator of Beta-methason was greater than this of Bromhexine Metabolit VIII.
D000551:Ambroxol / Q000494:pharmacology*; D000818:Animals; D001623:Betamethasone / Q000494:pharmacology*; D001964:Bromhexine / Q000031:analogs & derivatives*; D005342:Fibrinolysis; D008168:Lung / Q000032:analysis / Q000187:drug effects* / Q000196:embryology; D010960:Plasminogen Activators / Q000032:analysis; D051381:Rats
D000551:Ambroxol; D001623:Betamethasone; D010960:Plasminogen Activators; D001964:Bromhexine
Das Verhalten der gewebeständigen Plasminogenaktivatoren maternaler und fetaler Rattenlungen nach Applikation von Betamethason oder Bromhexine Metabolit VIII