[Experimentally produced neurogenic-interoreceptive hypertension in the rat].
A hypertension characterized by systolic and diastolic blood pressure rises and increase in heart rate was produced in albino rats by excluding sino-aortal baroreceptors. Cardiac output and peripheral resistance, measured unter barbital narcosis, exhibited no significant changes in the development of hypertension. With the only exclusion of aortal baroreceptors there occurred almost the same blood pressure rises as with sino-aortal deafferentiation. It is concluded therefore that this kind of partial elimination of baroreceptors involving a simplified operational technique and lower risk will suffice for many problems being studied in hypertension research.
D000818:Animals; D002302:Cardiac Output; D003714:Denervation; D004195:Disease Models, Animal; D006339:Heart Rate; D006973:Hypertension / Q000503:physiopathology*; D011311:Pressoreceptors / Q000503:physiopathology; D051381:Rats; D012849:Sinoatrial Node / Q000503:physiopathology / Q000601:surgery; D013997:Time Factors; D014655:Vascular Resistance
Experimentell erzeugte neurogen-interorezeptive Hypertonie bei der Ratte