Hypoglycaemia induced by adrenal gland neoplasia (Anderson's syndrome) : report of a case.
A patient with hypoglycaemia associated with an adrenal neoplasia (Anderson's syndrome) is reported. Endocrinological investigation showed increased secretion of cortisol and catecholamines as well as an increased urinary steroid excretion along with profound inhibition of both basal and stimulated insulin secretion. During IVGTT, Conard's coefficient was reduced. The hyperglycemic response to glucagon injection was blunted, suggesting that liver glycogen stores were decreased or unavailable.
D000310:Adrenal Gland Neoplasms / Q000150:complications*; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D005934:Glucagon / Q000494:pharmacology; D005947:Glucose / Q000494:pharmacology; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology*; D007328:Insulin / Q000097:blood; D008297:Male; D014044:Tolbutamide / Q000494:pharmacology
D001786:Blood Glucose; D007328:Insulin; D005934:Glucagon; D014044:Tolbutamide; D005947:Glucose