Lesions of midbrain raphe and ethanol narcosis in rats.
Serotonin -- depleting lesions involving nucleus raphe medianus markedly prolonged ethanol-induced sleep in rats. Lesioned animals showed increased general activity and decreased serotonin and 5-hydroxy-indoleacetic acid concentrations in the forebrain.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001679:Biogenic Amines / Q000032:analysis; D001923:Brain Chemistry / Q000187:drug effects; D000431:Ethanol / Q000494:pharmacology*; D006897:Hydroxyindoleacetic Acid / Q000032:analysis; D008297:Male; D008636:Mesencephalon / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology*; D051381:Rats; D012890:Sleep / Q000187:drug effects*; D013997:Time Factors
D001679:Biogenic Amines; D000431:Ethanol; D006897:Hydroxyindoleacetic Acid