[Ventilation, gas-exchange and pulmonary arterial pressure during aerosol inhalation of sympathicomimetics (author's transl)].
The effect of inhalation of Novodrin (beta-receptor-stimulus), Phenylephrine (alpha-receptor-stimulus) and of a mixture of both was tested in patients with chronic nonspecific respiratory syndrome. There was no significant difference of pulmonary arterial mean-pressure. Forced expiratory volume and vital capacity rose both after inhalation of Novdrin and after inhalation of the mixture. Nevertheless inhalation of the mixture can not be recommended because of a significant decrease of arterial oxygen-tension.
D000336:Aerosols; D001794:Blood Pressure / Q000187:drug effects; D001993:Bronchodilator Agents / Q000627:therapeutic use; D004338:Drug Combinations; D004341:Drug Evaluation; D005541:Forced Expiratory Volume; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008171:Lung Diseases / Q000188:drug therapy*; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D010656:Phenylephrine / Q000627:therapeutic use; D011651:Pulmonary Artery / Q000187:drug effects; D012138:Respiratory Therapy; D013566:Sympathomimetics / Q000627:therapeutic use*; D014797:Vital Capacity
D000336:Aerosols; D001993:Bronchodilator Agents; D004338:Drug Combinations; D013566:Sympathomimetics; D010656:Phenylephrine; D010100:Oxygen
Ventilation, Gasaustausch und pulmonal-arterieller Druck unter Aerosolinhalation von Sympathikomimetika