[Bile secretion intensity and the chemical makeup of the bile in white rats with liver dystrophy in the process of sodium selenite treatment].
In male rats with acute liver dystrophia, caused by carbon tetracloride, effect of sodium slentie (at doses of 1 mg and 10 mg per 100 g of body weight) on the bile secretion was studied. The drug normalized rapidly the functions of liver tissue, synthesis and excretion of bile acids, bilirubin secretion and excetion of cholesterol. Treatment with sodium selenite increased detoxication process in the organism, prevented death of the animals.
D000208:Acute Disease; D000818:Animals; D001646:Bile / Q000032:analysis / Q000378:metabolism*; D001647:Bile Acids and Salts / Q000032:analysis*; D001663:Bilirubin / Q000378:metabolism; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy / Q000503:physiopathology; D055598:Chemical Phenomena; D056486:Chemical and Drug Induced Liver Injury; D002621:Chemistry; D002784:Cholesterol / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D008107:Liver Diseases / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D051381:Rats; D012636:Secretory Rate / Q000187:drug effects; D012643:Selenium / Q000627:therapeutic use*; D013997:Time Factors
D001647:Bile Acids and Salts; D002784:Cholesterol; D012643:Selenium; D001663:Bilirubin
Intensivnost' zhelcheotdeleniia i khimicheskiĭ sostav zhelchi u krys pri distrofii pecheni v protsesse lecheniia selenitom natriia