Meptazinol: I.M. use in postoperative pain.
In a population of 39 patients, the new analgesic drug Meptazinol was tested in postoperative period at a dose of 100 mg I.M., administered only on request of the patient. Cardiovascular and respiratory parameters were not altered significantly. The onset of analgesia was rapid (+/- fifteen minutes) with a maximum reached after thirty minutes; the provided analgesia was good for about two hours as evaluated by the anesthetist and the nurse. The patient asked for a new dose only after about five hours.
D000700:Analgesics / Q000009:adverse effects / Q000627:therapeutic use*; D000758:Anesthesia; D001381:Azepines / Q000008:administration & dosage / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy*; D013997:Time Factors
D000700:Analgesics; D001381:Azepines