[Kinetics of proliferation of a mouse tumor cell line originating in the fetal large intestine].
The authors examine the kinetics of cellular proliferation of the cellular line STS, originating from adenocarcinoma, obtained after "spontaneous" malignization of a fragment from fetal colon. The cells of STS grow as a single layer and reach exponential phase on the 48th hour, but stationary phase-on the 96th hour of the culture. Time for doubling the number of the cells TD at the exponential phase of growth is 12 hours. The mitotic index varies from 7% at the exponential phase to 1,3% at the stationary. Time of cellular cycle and its phases, estimated by the curves of the marked mitosis, shows the following values: TGi=5.3 hours, Ts=6 hours, TG2=0.5 hour, TM=1,2 hour, and TC=13 hours. The authors discuss the differences in the data of TC and TD.
D000230:Adenocarcinoma / Q000196:embryology; D000818:Animals; D002460:Cell Line; D003110:Colonic Neoplasms / Q000196:embryology; D051379:Mice; D008807:Mice, Inbred BALB C; D008938:Mitosis
Kinetika na proliferatsiia na kletuchna liniia ot mishi tumor, proizkhozhdasht ot fetalno debelo chervo