Production and control of rabies vaccines made on diploid cells.
Introductory remarks on the advantages of antirabies vaccines obtained from human diploid cell cultures in comparison with brain tissue vaccine and duck embryo vaccine. The characteristics of these new types of vaccine are: (i) high antigenicity, (ii) rapid development of antibodies, (iii) absence of adverse reactions even when the booster inoculation was given two years later. The disadvantage is the high cost of production to obtain a highly purified product.
D000956:Antigens, Viral / Q000008:administration & dosage; D002478:Cells, Cultured; D004171:Diploidy; D004467:Economics; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D011786:Quality Control; D011819:Rabies Vaccines / Q000494:pharmacology / Q000592:standards*; D011820:Rabies virus / Q000276:immunology; D014613:Vaccines, Attenuated / Q000592:standards; D014776:Virus Cultivation / Q000379:methods*
D000956:Antigens, Viral; D011819:Rabies Vaccines; D014613:Vaccines, Attenuated