In vivo acylation of triglycerides and phosphoglycerides of liver subcellular fractions with palmitate-1-14C in rats fed vitamin A.
Incorporation of palmitate-1-14C into liver and its mitochondrial, and microsomal triglycerides and phosphoglycerides of rats fed 100000 I.U. of vitamin A for two days has been studied. Feeding of vitamin A significantly increased triglycerides in liver and its mitochondrial, microsomal and supernatant fractions as compared to the controls. A significant increase in total phospholipids and phosphatidyl choline was noted in liver mitochondrial and microsomal fractions of vitamin A fed rats. The incorporation of palmitate-1-14C (counts/min/liver) into triglycerides of liver mitochondrial, microsomal and supernatant fractions of vitamin A fed rats was significantly higher, whereas in phosphatidyl ethanolamine and phosphatidyl choline it was not significantly different from the controls.
D000215:Acylation; D000818:Animals; D002458:Cell Fractionation; D005994:Glycerophosphates / Q000096:biosynthesis*; D008099:Liver / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D008930:Mitochondria, Liver / Q000378:metabolism; D010168:Palmitates / Q000378:metabolism*; D010169:Palmitic Acids / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000096:biosynthesis; D010714:Phosphatidylethanolamines / Q000096:biosynthesis; D051381:Rats; D014280:Triglycerides / Q000096:biosynthesis*; D014801:Vitamin A / Q000494:pharmacology*
D005994:Glycerophosphates; D010168:Palmitates; D010169:Palmitic Acids; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D014280:Triglycerides; D014801:Vitamin A