title: Studies on the uptake, metabolism, and release of endogenous and exogenous chemicals by use of the isolated perfused lung.
abstract: The isolated perfused lung is a valuable tool for studying many lung functions. The kinds of information one can obtain from the isolated perfused lung are illustrated by examples from our studies on the uptake, accumulation, and metabolism of endogenous and exogenous chemicals.
mesh_terms: D000818:Animals; D003911:Dextrans / Q000378:metabolism; D007099:Imipramine / Q000378:metabolism; D066298:In Vitro Techniques; D007700:Kinetics; D008168:Lung / Q000378:metabolism*; D008691:Methadone / Q000378:metabolism; D008722:Methods; D010477:Perfusion; D011092:Polyethylene Glycols / Q000378:metabolism; D011453:Prostaglandins / Q000378:metabolism; D011817:Rabbits; D013997:Time Factors
chemical_list: D003911:Dextrans; D011453:Prostaglandins; D011092:Polyethylene Glycols; D007099:Imipramine; D008691:Methadone