[Research on heterocyclic compounds. V. Imidazo/2,1-b/thiazole-6-ascetic acids and imidazo/2,1-b/benzothiazole-2-acetic acids].
We have prepared a group of ethyl imidazo [2,1-b]thiazole-6- and imidazo[2,1-b]benzothiazole-2-acetates, starting from some substituted 2-aminothiazoles and 2-aminobenzothiazoles, by reaction with ethyl 4-bromoacetoacetate. From these esters we have obtained the corresponding acetic acids, and we have tested their anti-inflammatory activity.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis*; D007093:Imidazoles / Q000138:chemical synthesis; D007202:Indicators and Reagents; D051381:Rats; D013844:Thiazoles / Q000138:chemical synthesis*
D000893:Anti-Inflammatory Agents; D007093:Imidazoles; D007202:Indicators and Reagents; D013844:Thiazoles
Ricerche su composti eterociclici. V. Acidi imidazo[2,1-b]-tiazol-6-acetici e imidazo[2,1-b] benzotiazol-2-acetici