title: [Detection of major genes for quantitative morphologic characteristics on family material, sib pairs and parent-child pairs, using as an example head length in man].
abstract: The detection of major genes affecting quantitative morphological characters from data of families, sib-pairs and parent-child pairs (with the example of head length in man). The major genes of human head length are defined utilizing three different combinatorical methods of maximum likelihood estimation. To prove the discriminatory power of methods, it is necessary in further research to work with empirical or simulated sets of multivariate data of which the genetical structure is known.
mesh_terms: D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D006257:Head / Q000033:anatomy & histology*; D006801:Humans; D010375:Pedigree; D010641:Phenotype; D011336:Probability
vernacular_title: Die Erkennung von Hauptgenen quantitativer morphologischer Merkmale mit Familienmaterial, Geschwisterpaaren und Elter-Kind-Paaren am Beispiel der Kopflänge des Menschen