[Effect of early visual deprivation on the free amino acid and protein content in the brain formations of dogs].
10 days old dogs were subjected to bilateral enucleation of eyeballs. When the dogs became 3 months old, content of free amino acids and total proteins was determined in tissue of brain formation of optic system (optic cortex-field 17, external knee body and front bigeminal bodies). locomotor and partietal regions of brain cortex and cerebellum. As compared with the control group, the amount of proteins was distinctly decreased in optic cortex and increased in external knee body. In all he brain formations studied content of arginine, lysine, gamma-aminobutyric acid, cysteine (except of external knee body) and histidine (except of external knee body and front bigeminal bodies) was distinctly increased. The decrease in content of glutamic acid was observed only in front bigeminal bodies and aspartic acid -- in cerebellum. Glutathione was accumulated selectively in front bigeminal bodies and in locomotor cortex.
D000367:Age Factors; D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D001766:Blindness / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D002531:Cerebellum / Q000378:metabolism; D004285:Dogs; D005609:Free Radicals; D009044:Motor Cortex / Q000378:metabolism; D010296:Parietal Lobe / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*; D012683:Sensory Deprivation; D014793:Visual Cortex / Q000378:metabolism
D000596:Amino Acids; D005609:Free Radicals; D011506:Proteins
Vliianie ranneĭ zritel'noĭ deprivatsii na soderzhanie svobodnykh aminokilsot i belkov v obrazovaniiakh mozga sobak