Linkage of the cadmium resistance locus to loci on mouse chromosome 12.
The autosomal recessive gene cdm that confers resistance to cadmium-induced testicular necrosis in certain inbred strains of mice has been mapped on Chromosome 12 near varitint-waddler (Va). A 3-point cross involving Va, cdm, and amylase-1 (Amy-1) indicated the following gene order and approximate distances: Va-8-cdm-17-Amy-1. The cdm locus is the first polymorphic locus to be placed on Chromosome 12.
D000818:Animals; D002104:Cadmium / Q000494:pharmacology*; D002874:Chromosome Mapping; D002875:Chromosomes; D003433:Crosses, Genetic; D005260:Female; D005808:Genes, Recessive; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D013737:Testis / Q000187:drug effects*
D002104:Cadmium