Ovarian refractoriness to gonadotropins in cases of inappropriate lactation: restoration of ovarian function with bromocryptine.
In ten patients with amenorrhea-galactorrhea who had hyperprolactinemia, ovulation could not be induced clomiphene citrate or exogenous gonadotropins. Treatment with bromocryptine in eight of these patients resulted in suppression of PRL in all, cessation of galactorrhea and ovulation in seven and conception in five.
D000568:Amenorrhea / Q000097:blood / Q000188:drug therapy*; D001971:Bromocriptine / Q000627:therapeutic use*; D004873:Ergolines / Q000627:therapeutic use*; D005260:Female; D005298:Fertility; D005687:Galactorrhea / Q000097:blood / Q000188:drug therapy*; D006065:Gonadotropins, Pituitary / Q000097:blood; D006801:Humans; D007775:Lactation Disorders / Q000188:drug therapy*; D008596:Menotropins / Q000627:therapeutic use; D010053:Ovary / Q000502:physiology*; D010060:Ovulation / Q000187:drug effects; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*; D013972:Thyrotropin / Q000097:blood
D004873:Ergolines; D006065:Gonadotropins, Pituitary; D001971:Bromocriptine; D008596:Menotropins; D011388:Prolactin; D013972:Thyrotropin