Persistent and atypical lobules in the human breast may be precancerous.
Persistent human mammary lobules (PL) remaining after the menopause, and certain atypical lobules (ALA) are morphologically similar to the common preneoplastic hyperplastic alveolar nodule (HAN) of mice of strains having a high incidence of mammary carcinoma. This and other evidence suggest that like the HAN of mice human PL and ALA are precancerous.
D000818:Animals; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008321:Mammary Glands, Animal / Q000473:pathology*; D051379:Mice; D008815:Mice, Inbred Strains; D011230:Precancerous Conditions / Q000175:diagnosis / Q000473:pathology*