[Non-specific effects of a drug study in hypertensive patients].
During the first phase of a drug study, 33 hypertensive patients received 2 placebo tablets daily for 2 weeks as the sole treatment. Analysis of the blood pressure readings during this placebo phase shows that the study in itself creates a psychological climate which tends to decrease blood pressure. This effect should be taken into account when analyzing results of drug studies; only in studies with a double blind design is drug effect adequately judged.
D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010919:Placebos
D000959:Antihypertensive Agents; D010919:Placebos
Effets non spécifiques d'une étude médicamenteuse chez des malades hypertendus