[Lose-dose treatment with vitamin A in prevention of stress ulcer in swine].
Hemorrhagic shock in 8 piglets (mean AoBP 40 mm Hg for 3 h) was followed by severe stress-induced gastric mucosal lesions (Gr-I). When vitamin A was administered simultaneously (50,000 IE/kg = Gr. II, n = 6 and 5,000 IE/kg = Gr. III, n = 7) during the procedure, no stress lesions were observed. The study shows that the simultaneous application of vitamin A during hemorrhagic shock, in a reasonable clinical dosage, protects the gastric mucosa against stress-induced lesions.
D000818:Animals; D012771:Shock, Hemorrhagic / Q000150:complications; D013276:Stomach Ulcer / Q000517:prevention & control*; D013312:Stress, Physiological / Q000150:complications*; D013552:Swine; D014801:Vitamin A / Q000008:administration & dosage* / Q000627:therapeutic use
D014801:Vitamin A
Niedrigdosierte Vitamin A-Behandlung zur Stressulcusprophylaxe beim Schwein.