Serum and bile modifications in the guinea-pig following chronic treatment with PGE1 and PGE2.
PGE1 increases cholesterolemia without lipemia modifications. In bile there are not modifications in cholesterol levels and total lipids appear diminished. PGE2 raise the lipemia and have no effect in cholesterolemia, moreover bile cholesterol and total lipids exhibit no changes. Both PGE1 and PGE2 decreased the bile volume.
D000818:Animals; D001646:Bile / Q000187:drug effects* / Q000378:metabolism; D002784:Cholesterol / Q000097:blood* / Q000378:metabolism; D005260:Female; D006168:Guinea Pigs; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood; D008297:Male; D011458:Prostaglandins E / Q000494:pharmacology*
D008055:Lipids; D011458:Prostaglandins E; D002784:Cholesterol