[Analgesics and the kallikrein-kinin system].
The mechanism of analgesic actions of aspirin, aminopyrine and morphine was investigated in reference to the kallikrein-kinin system and the results suggested that the analgesic actions of these agents are definitely related with the peripheral kallikrein-kinin activity. The central action of kinin appears to differ from the peripheral action.
D000632:Aminopyrine / Q000494:pharmacology*; D000818:Animals; D001241:Aspirin / Q000494:pharmacology*; D004285:Dogs; D005260:Female; D006801:Humans; D007610:Kallikreins / Q000032:analysis / Q000037:antagonists & inhibitors*; D007705:Kinins / Q000032:analysis / Q000037:antagonists & inhibitors*; D008297:Male; D051379:Mice; D009020:Morphine / Q000494:pharmacology*; D051381:Rats; D014590:Uterine Contraction / Q000187:drug effects
D007705:Kinins; D000632:Aminopyrine; D009020:Morphine; D007610:Kallikreins; D001241:Aspirin