Studies on a patient with iminopeptiduria. I. Identification of urinary iminopeptides.
A patient suffering from recurrent ulcers on the legs was found to excrete large amounts of iminodipeptides in the urine. Among the iminodipeptides excreted, Glu-Hyp, Asp-Pro, Glu-Pro, Leu-Hyp, Gly-Pro, Thr-Pro, Ser-Pro, Ala-Pro, Val-Pro, Ile-Pro, Leu-Pro, and Phe-Pro were identified and their quantities estimated. Some of the iminopeptides had to be synthesized for purposes of identification.
D000592:Amino Acid Metabolism, Inborn Errors / Q000652:urine*; D002648:Child; D004151:Dipeptides / Q000138:chemical synthesis / Q000652:urine*; D005260:Female; D006801:Humans; D007097:Imines / Q000652:urine*; D066298:In Vitro Techniques; D012883:Skin Ulcer / Q000652:urine; D013055:Spectrophotometry, Infrared
D004151:Dipeptides; D007097:Imines