[Role of visual impulsation on the age-dependent receptor properties of synaptosomal membranes].
An investigation was made into the activity of interaction of serotonin and tryptamine with synaptosomes isolated from the visual system of the rabbit brain. It has been found that the synaptosomes of the visual cortex and the anterior colliculi of normal rabbits are characterized by a higher activity in indoleamines binding than those of other parts of the cortex. Early visual deprivation caused a drop in the activity of interaction between the indoleamines and synaptosomes of all the investigated brain regions, more pronounced in the case of the synaptosomes of the visual analyser structures. Recovery of the visual function helped to normalize the activity of the process. The above regular relationships between visual impulse activity and the activity of the transmitter--receptor interaction lead to the conclusion that serotonin plays a specific, apparently neuro-transmitting part in the visual system.
D000367:Age Factors; D000818:Animals; D009430:Neural Analyzers / Q000378:metabolism; D011817:Rabbits; D011985:Receptors, Serotonin / Q000378:metabolism*; D012683:Sensory Deprivation; D012701:Serotonin / Q000378:metabolism; D013477:Superior Colliculi / Q000378:metabolism; D013574:Synaptosomes / Q000378:metabolism*; D014363:Tryptamines / Q000378:metabolism; D014785:Vision, Ocular; D014793:Visual Cortex / Q000378:metabolism; D014795:Visual Pathways / Q000378:metabolism* / Q000648:ultrastructure
D011985:Receptors, Serotonin; D014363:Tryptamines; D012701:Serotonin
O roli zritel'noĭ impul'satsii v vozrastnom stanovlenii retseptornykh svoĭstv membran sinaptosom