[Effect of hydrocortisone on sodium and potassium distribution in the sections of the cerebral cortex of rats after their electric stimulation].
Sections of the rat brain cortex were incubated in various physiological media using container-electrodes, similar to the McIlwain's type. The shifts of sodium and potassium distribution between the extra- and intracellular spaces of the slices after different stimulation parameters and the subsequent restoration were measured. The administration of hydrocortisone (for 7 days, 5 mg/100 g daily) usually increased the response of the slices to the stimulation in incubation in the glutamate devoid medium. When 0.2--0.5 mM of glutamate was added to the media the effect of hydrocortisone disappeared. Possible physiological significance of the mentioned results is discussed.
D000818:Animals; D001834:Body Water / Q000378:metabolism; D002540:Cerebral Cortex / Q000378:metabolism*; D002712:Chlorides / Q000378:metabolism; D003470:Culture Media; D004558:Electric Stimulation; D006854:Hydrocortisone / Q000494:pharmacology*; D008297:Male; D011188:Potassium / Q000378:metabolism*; D051381:Rats; D012964:Sodium / Q000378:metabolism*
D002712:Chlorides; D003470:Culture Media; D012964:Sodium; D011188:Potassium; D006854:Hydrocortisone
Vliianie gidrokortizona na raspredelenie natriia i kaliia v srezakh hory mozga krys pri elektrostimuliatsii srezov.