[Steroid receptors and hormonal receptivity. New pharmacological and therapeutic approaches applicable to the control of fertility].
The definition and main characteristics of the steroid hormone receptors are given. One may note a relationship between hormonal receptivity and the physiological changes in the concentration of the receptors in the target organs. The distribution of the various receptors is given in detail showing the existence of (a) different receptors for the same hormone in different target cells; (b) different receptors for different hormones in the same cells; (c) different receptors for the same hormone in the same cell. A new pharmacological approach is proposed based on differentiation of receptivities from which there results a dissociation of the therapeutic effects.
D004347:Drug Interactions; D005260:Female; D005298:Fertility; D006801:Humans; D011960:Receptors, Estrogen / Q000502:physiology; D011980:Receptors, Progesterone / Q000502:physiology; D011987:Receptors, Steroid / Q000502:physiology*
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D011987:Receptors, Steroid
Récepteurs des stéroïdes et "réceptivité" hormonale. Nouvelles approches pharmacologiques et thérapeutiques applicables au contrôle de la fertilité