title: Electrocardiographic studies during hypotensive anaesthesia using sodium nitroprusside.
abstract: Multiple lead electrocardiographic recordings from 20 patients were studied before, during and after a period of induced hypotension with sodium nitroprusside. Although small changes in ST segment and T wave were observed in 9 patients, none of these persisted into the postoperative period. Other significant changes were confined to a temporary disturbances of cardiac rhythm in 2 patients, both of whom spontaneously reverted to sinus rhythm during the anaesthetic. Our findings indicate that there are no permanent ischaemic myocardial changes associated with induced hypotension using sodium nitroprusside.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D001794:Blood Pressure / Q000187:drug effects; D004562:Electrocardiography; D005260:Female; D005292:Ferricyanides / Q000494:pharmacology; D006321:Heart / Q000187:drug effects; D006801:Humans; D007023:Hypotension, Controlled; D008297:Male; D008875:Middle Aged; D009599:Nitroprusside / Q000494:pharmacology; D013997:Time Factors
chemical_list: D005292:Ferricyanides; D009599:Nitroprusside