[On the determination of triamterene, hydroxythiamterene and hydroxytriamterene sulphate ester in biologica material by direct evaluation of thin-layer chromatograms (author's transl)].
The quantitative measurement of 2,4,7-triamino-6-phenylpteridine (triamterene), as well as its metabolites hydroxytriamterene and hydroxytriamterene sulphate ester, is described. Estimation of urine, plasma and faecal samples was achieved by a direct fluorometric method following separation on kieselgel plates. The procedure allows the simultaneous assay of the three substances on the plate without the need for previous chromatographic separation or derivatisation.
D002855:Chromatography, Thin Layer; D006801:Humans; D008722:Methods; D013050:Spectrometry, Fluorescence; D014223:Triamterene / Q000031:analogs & derivatives* / Q000032:analysis*
D014223:Triamterene
Uber die Bestimmung von Triamteren, Hydroxytriamteren und Hydroxytriamteren-schwefelsäureester in biologischem Material durch direkte Auswertung von Dünnschichtchromatogrammen