[Histochemical study of the activity of aspartate aminotransferase in the spinal cord, the medulla oblongata and the central cerebellar nuclei of several vertebrates].
The aspartate aminotransferase activity (AAT) is reserched into the spinal cord, the medulla oblongata and the cerebellar nuclei of the rat, chicken, Lacerta lepida and Bufo calamitas. It's proved that the AAT activity shows in many locations, that are mainly: 1. In the nerve fibers 2. In the cytoplasmic membrane, and in the nuclear membrane of the neurons 3. In all neuronal cytoplasm, and 4. In the mitochondria of neurons and choroid plexus cells. The results base the idea that there's more than one pool of glutamic acid in relation to that AAT. It's suggested that the role that AAT plays is different in everyone of the described locations, and may be it's connected with transport phenomenons in the membrane, with energetic function on the mitochondria and with functions of the nerve impulse transmission in the synapsis. We remark, finally, the interest that the enzymatical works can have the time comming to establish homologies among similar structures of several animal's nervous system.
D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism*; D002025:Bufonidae; D002529:Cerebellar Nuclei / Q000201:enzymology*; D002645:Chickens; D003594:Cytoplasmic Granules / Q000201:enzymology; D008526:Medulla Oblongata / Q000201:enzymology*; D051379:Mice; D009412:Nerve Fibers / Q000201:enzymology; D009474:Neurons / Q000201:enzymology; D011817:Rabbits; D051381:Rats; D013116:Spinal Cord / Q000201:enzymology*
D001219:Aspartate Aminotransferases
Etude histochimique de l'activité aspartate amino-transférase dans la moëlle, le bulbe et les noyaux cérébelleux centraux de quelques vertébrés