Preliminary report on the use of ethyl apovincaminate in affections of the eyeground.
26 ophthalmological patients have been given daily doses of three times 1 tablet (15 mg) ethyl apovincaminate (RGH-4405, Cavinton) for periods of from two weeks to three months. Improvement of visual acuity lasted as long as the course of treatment, in agreement with the results of other authors. On Cavinton effect blood flow increased in the retinal precapillary and capillary system, supply of hypoxic areas improved. Improvement noted in choroid sclerosis bears witness to the effect of Cavinton on choroid capillaries.
D000328:Adult; D000368:Aged; D002829:Choroid / Q000098:blood supply; D005128:Eye Diseases / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D012039:Regional Blood Flow / Q000187:drug effects; D012164:Retinal Diseases / Q000188:drug therapy; D012171:Retinal Vessels / Q000187:drug effects; D014748:Vinca Alkaloids / Q000627:therapeutic use*; D014792:Visual Acuity / Q000187:drug effects
D014748:Vinca Alkaloids