An evaluation of the use of topical anesthetics and low concentrations of phenylephrine HCl for mydriasis.
When used in conjunction with a topical anesthetic, low concentrations of phenylephrine HCl produce the same degree of mydriasis as is produced by higher concentrations of the drug used alone. Contrary to previously published reports, however, there is no evidence to suggest that the use of lower concentrations lessens the risk of adverse reactions. The analysis of available information given here suggests that the risks may in fact be increased when an anesthetic is used.
D000287:Administration, Topical; D000779:Anesthetics, Local / Q000008:administration & dosage*; D005069:Evaluation Studies as Topic; D006801:Humans; D007429:Intraocular Pressure; D010656:Phenylephrine / Q000008:administration & dosage* / Q000009:adverse effects; D011680:Pupil / Q000187:drug effects*
D000779:Anesthetics, Local; D010656:Phenylephrine