A multi-centre general practitioner assessment of butriptyline hydrochloride ('Evadyne').
A multi-centre open study in general practice was carried out to assess the efficacy of and incidence of side-effects with the tricyclic antidepressant, butriptyline. Of a series of 153 patients with non-psychotic depression, with or without anxiety, 105 (69%) were judged as having a good or fair response to treatment with 75 mg to 150 mg butriptyline daily. Side-effects of an anticholinergic nature were seen in 13.7% of patients, but the incidence decreased to less than 4% in the 101 patients receiving treatment for over 7 weeks.
D000293:Adolescent; D000328:Adult; D000368:Aged; D003863:Depression / Q000188:drug therapy; D003986:Dibenzocycloheptenes / Q000009:adverse effects / Q000627:therapeutic use*; D004341:Drug Evaluation; D005194:Family Practice; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D003986:Dibenzocycloheptenes