[Duration of unilaterally organized trace excitation following administration of sedative and stimulating substances].
In experiments on dogs with symmetrical parts of the tongue brought out by Abuladze method, a study was made of the duration of trace excitation after administration of drugs of a sedative (bromine, amizyl) and stimulating (caffeine, ezerine) effect. It has been found that with changes of symmetrically organized reflexes during the action of the sedative drugs the duration of trace excitation is halved or reduced to a third, and the adequate unilateral reaction is sooner restored. The action of the stimulating drugs, the duration of traces increases and the unilateral conditioned reaction becomes bilateral. It has been assumed that change in the duration of trace excitation, resulting from the indicated pharmacological tests is due to the influence of the drugs on the processes of interhemispheric irradiation and concentration.
D000818:Animals; D001535:Benactyzine / Q000494:pharmacology*; D001965:Bromides / Q000494:pharmacology*; D002110:Caffeine / Q000494:pharmacology*; D003214:Conditioning, Classical / Q000187:drug effects*; D004285:Dogs; D007839:Functional Laterality; D010830:Physostigmine / Q000494:pharmacology*; D012472:Salivation; D013016:Sound; D014059:Tongue / Q000502:physiology
D001965:Bromides; D002110:Caffeine; D001535:Benactyzine; D010830:Physostigmine
Dlitel'nost' sokhraneniia odnostoronne organizovannogo sledovogo vozbuzhdeniia pri vvedenii sedativnykh i stimuliruiushchikh veshchestv