title: [Causes of death of patients with breast cancer (according to the materials of the Oncological Research Center of the USSR AMS for the period 1953-1975)].
abstract: The article presents results of investigations of 207 case records and protocols of autopsies of deceased patients who suffered from breast cancer, covering the period from 1953 to 1972 (materials of the USSR AMS Oncological Research Centre). It was established that in 154 patients (74.4%) the cause of death was the progress of the main disease, the most common and "typica" causes of death being pulmonary-cardiac, renal insufficiency (as a result of metastatic lesions of the above mentioned organs) and complications associated with metastases of breast cancer in to the brain and its meninx. In 39 patients (18.8%) the cause of death was directly associated with therapy complications, 14 patients died of diseases not connected with carcinoma of the mammary gland. The structure of causes in the group of deceased patients who when alive suffered from cancer of the mammary gland and who survived 10 and more years from the moment of establishing the diagnosis and carrying out primary treatment (11 observations) was found to be the same as that for the whole group of observations.
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000209:etiology / Q000401:mortality*; D001943:Breast Neoplasms / Q000150:complications / Q000401:mortality* / Q000628:therapy; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006331:Heart Diseases / Q000209:etiology / Q000401:mortality; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology / Q000401:mortality*; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011183:Postoperative Complications / Q000401:mortality; D012131:Respiratory Insufficiency / Q000209:etiology / Q000401:mortality
vernacular_title: Prichiny smerti bol'nykh rakom molonchoĭ zhelezy (po materialam Onkologicheskogo nauchnogo tsentra AMN SSSR za period 1953-1975 g)