[Significance of the endodermal sinus tumor (Teilum) and of simplified teratoma of vitelline determination].
The histogenesis of yolk-sac tumors has been explained by a selective cloning for extra-embryonic entoblast amongst totipotent carcinoma stemcells. The diverses appearances of the tumor growths are expressed mainly in the range of cyto-differentiations of entoblastic tissue rather than in their ability to form structures which mimick the yolk-sac. The process is clearly apparent in embryoids which are becoming disorganized and during the course of experimentally induced mouse parietal endodermal carcinoma. The latter's appearance is strong evidence that the laws of specificity are obeyed. Human tumors should be analyzed through human embryology. Some paradoxical aspects emerge occasionally due to the angiogenesic capabilities of the neoplastic vitelline tissue, and to the correlations of this tissue with the stromal vascular response.
D000818:Animals; D004707:Endoderm; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D009368:Neoplasm Transplantation; D013724:Teratoma / Q000098:blood supply / Q000196:embryology / Q000473:pathology*; D013736:Testicular Neoplasms / Q000098:blood supply / Q000196:embryology / Q000473:pathology; D014185:Transplantation, Isogeneic; D014817:Vitelline Membrane
Signification de la tumeur des sinus endodermiques (Teilum) et des tératomes simplifiés à détermination vitelline