[Effect of intravenous disopyramide on the hemodynamics of patients hospitalized in intensive care units].
A single dosis of disopyramide (100 mg), given intravenously in 10 min to 30 patients admitted in the coronary or respiratory care unit, induces a reduction of cardiac output of 13.4%, which is highly statistically significant, without altering the systemic and pulmonary pressures. The heart rate is also slightly diminished.
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D004206:Disopyramide / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007275:Injections, Intravenous; D008168:Lung / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology; D011725:Pyridines / Q000494:pharmacology*; D012131:Respiratory Insufficiency / Q000503:physiopathology; D014655:Vascular Resistance / Q000187:drug effects
D011725:Pyridines; D004206:Disopyramide
Effets du disopyramide intraveineux sur l'hémodynamique de patients hospitalisés en unités de soins intensifs