title: [Morphogenetic function of the nuclei in the early development of the common freshwater snail, Limnaea stagnalis].
abstract: The early embryos L. stagnalis were placed in the actinomycin solution at the successive developmental stages. The permeability to actinomycin was previously increased by the pricking through egg capsules. The inactivation of nuclei by actinomycin up to the stage of 12 blastomeres resulted in the arrest of development at the 22 cell stage. The inactivation of nuclei at the subsequent development stages resulted in the developmental arrest at later stages. These data suggest that the embryonic development up to the 22 cell stage is provided by the nuclear function during oogenesis. The morphogenetic nuclear function of the embryo begins at the stage of 12 blastomeres and provides the embryonic development beyond the 22 cell stage.
mesh_terms: D000818:Animals; D002463:Cell Membrane Permeability / Q000187:drug effects; D002467:Cell Nucleus / Q000187:drug effects / Q000502:physiology*; D003609:Dactinomycin / Q000494:pharmacology; D005260:Female; D008195:Lymnaea / Q000196:embryology*; D009024:Morphogenesis; D009866:Oogenesis / Q000187:drug effects; D010063:Ovum / Q000187:drug effects; D011691:Puromycin / Q000494:pharmacology
chemical_list: D003609:Dactinomycin; D011691:Puromycin
vernacular_title: O morfogeneticheskoĭ funktsii iader v rannem razvitii bol'shogo prudovnika Limnaea stagnalis.