title: [Experimental sensitization with an extract of Dermatophagoides pteronyssinus ticks].
abstract: Immunogenic properties of Dermatophagoides pteronyssinus ticks were studied in subcutaneous injection of the antigen to guinea pigs and rabbits. Marked changes in the immunological reactivity of the animal organism were revealed; these changes were accompanied by production of agglutinating, sensitizing the mast cells and precipitating (in rabbits) antibodies, and by the development of hypersensitivity of the immediate and delayed type.
mesh_terms: D000372:Agglutination Tests; D000818:Animals; D000906:Antibodies / Q000032:analysis; D000937:Antigen-Antibody Reactions / Q000187:drug effects; D000941:Antigens / Q000008:administration & dosage* / Q000302:isolation & purification; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed / Q000276:immunology; D006969:Hypersensitivity, Immediate / Q000276:immunology; D007114:Immunization; D008407:Mast Cells / Q000276:immunology; D011233:Precipitin Tests; D011817:Rabbits; D051381:Rats; D013987:Ticks / Q000276:immunology*; D013997:Time Factors
chemical_list: D000906:Antibodies; D000941:Antigens
vernacular_title: Eksperimental'naia sensibilizatsiia ékstraktom kleshcheĭ Dermatophagoides pteronyssinus