[Effect of acetylcholine on active ion transport across the epithelium of frog skin].
The effect of acetylcholine on isolated skin of Rana ridibunda is studied. The application of acetylcholine (1 mM) in Ringer's solution, washing the outer aspect of the skin, causes slow and smooth increase in the preparation's current and potential. Upon acetylcholine addition to the solution on the inner aspect, the increase of the above parameters runs a course along a two-peaked curve. It is presumed that in the latter case acetylcholine, prior to exert a direct effect on the epithelium, influences some of the nerve or glandular formations in the skin corium.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D001001:Anura; D001693:Biological Transport, Active / Q000187:drug effects; D004848:Epithelium / Q000187:drug effects; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects; D011898:Ranidae; D012869:Skin Absorption / Q000187:drug effects*
D000109:Acetylcholine
Vliianie na atsetilkholina vurkhu aktivniia transport na ĭoni prez epitela na zhabeshka kozha.