[Effect of the feeding frequency on protein metabolism in the skeletal muscles and liver of white rats].
A comparative investigation into the influence of 3 and 5 times a day feeding on the protein metabolism in the skeletal muscles and liver of albino rats was carried out. The dietary regimen with a greater frequency of feeding was found to be consonant with a higher concentration of total aminonitrogen and with a number of essential amino acids, as well as with a higer activity of asparate-aminotransferase in the study tissues. Along with this, there occurs a more intensive incorporation of radioactive leucine in the total proteins and basic proteinic fractions of the skeletal muscles and also augments specific radioactivity of the poly-A-containing informative RNA in polysomes and is in evidence shifting the ribosomal spectrum toward formation of polysomal complexes. The activation of proteinosynthesis observed with increasing frequency of feeding may be ascribed to a more uniform diurnal supply of nutrients to the organism.
D000596:Amino Acids / Q000378:metabolism; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D004044:Dietary Proteins / Q000378:metabolism*; D007930:Leucine / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008297:Male; D009124:Muscle Proteins / Q000378:metabolism; D009132:Muscles / Q000378:metabolism*; D009963:Orotic Acid / Q000378:metabolism; D014176:Protein Biosynthesis; D012313:RNA / Q000378:metabolism; D051381:Rats; D013997:Time Factors
D000596:Amino Acids; D004044:Dietary Proteins; D009124:Muscle Proteins; D009963:Orotic Acid; D012313:RNA; D007930:Leucine
Vliianie kratnosti pitaniia na obmen belkov v skeletnykh myshtsakh i pecheni belykh krys