A glycoprotein precipitate in the blood vessels of kidneys stored in cold homologous blood.
Dog kidneys were stored three hours at 4 degrees C in heparinized homologous blood. Their histological examination revealed the presence of a homogeneous precipitate in the glomerular capillaries and afferent and efferent arterioles, and histochemical analysis indicated that it consisted of glycoprotein. It is tentatively suggested that the substance is cryoglobulin, a conclusion supported by the disappearance of the deposit on reimplantation of the kidney.
D000818:Animals; D001158:Arteries / Q000378:metabolism*; D001160:Arterioles / Q000378:metabolism*; D001769:Blood; D002196:Capillaries / Q000378:metabolism* / Q000648:ultrastructure; D003080:Cold Temperature; D004285:Dogs; D006023:Glycoproteins / Q000378:metabolism*; D006651:Histocytochemistry; D007678:Kidney Glomerulus / Q000098:blood supply*; D009926:Organ Preservation; D014021:Tissue Preservation
D006023:Glycoproteins