title: [Activation of the rate of enzymatic formation of sulfhydryl groups by serotonin].
abstract: Administration of serotonin into animals and incubation of serotonin with homogenates stimulated disulphide reductase in liver and spleen tissues. The effect of serotonin in vivo was probably mediated by liberation of catecholamines; it was eliminated by pyrilene and reserpine. The reflex mechanisms of catecholamines liberation were mediated by serotonin through serotonin-receptors of T-type. Alteration in the disulphide reductase activity correlated with the increased content of thiols after administration of serotonin.
mesh_terms: D000818:Animals; D002395:Catecholamines / Q000378:metabolism; D004220:Disulfides; D066298:In Vitro Techniques; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D051379:Mice; D009020:Morphine / Q000494:pharmacology; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism*; D010393:Pempidine / Q000494:pharmacology; D011985:Receptors, Serotonin / Q000187:drug effects; D012110:Reserpine / Q000494:pharmacology; D012701:Serotonin / Q000494:pharmacology*; D013154:Spleen / Q000201:enzymology / Q000378:metabolism*; D013438:Sulfhydryl Compounds / Q000378:metabolism*
chemical_list: D002395:Catecholamines; D004220:Disulfides; D011985:Receptors, Serotonin; D013438:Sulfhydryl Compounds; D012701:Serotonin; D009020:Morphine; D012110:Reserpine; D010088:Oxidoreductases; D010393:Pempidine
vernacular_title: Aktivirovanie serotoninom skorosti fermentativnogo obrazovaniia sul'fgidril'nykh grupp