[Intestinal absorption from therapeutic iron doses (author's transl)].
On a total of 105 persons with normal iron stores, iron depletion, and iron deficiency the intestinal absorption from therapeutic iron doses (100 mg Fe and 50 mg Fe as ferrous glycocoll sulphate) of a special galenic form was measured. The measurements were performed by means of a whole-body counter and preparations labelled with radio-iron (59Fe). Mean values of absorption rates from 100 mg Fe in healthy males were 5.0% and in healthy females 5.6% whereas in latent iron deficiency and in iron deficiency anemia mean values of 10% and 13% were obtained, respectively. The maximum absorption rate of 20 to 25% is reached already in the late stage of latent iron deficiency. Advancing severeness of iron deficiency is not followed by an increase of iron absorption. Investigations on 21 persons showed no significant difference between absorption rates of the galenic preparations used when administered orally before or after breakfast, respectively.
D000747:Anemia, Hypochromic / Q000188:drug therapy / Q000378:metabolism; D005260:Female; D006801:Humans; D007408:Intestinal Absorption; D007501:Iron / Q000378:metabolism* / Q000627:therapeutic use; D000090463:Iron Deficiencies; D008297:Male
D007501:Iron
Intestinale Eisenabsorption aus therapeutischen Dosen