[Lactate dehydrogenase and glucose-6-phosphate dehydrogenase activity in the erythrocytes in diabetes mellitus].
In human erythrocytes activities of glucose-6-phosphate and lactate dehydrogenases were decreased approximately 2-fold in moderately severe and critical forms of diabetes mellitus, as compared with normal state. The lactate dehydrogenase activity was more distinctly decreased than the glucose-6-phosphate dehydrogenase activity. General medical treatment increased the activity of the enzymes (which catalyzed the ATP formation in erythrocytes) and normalized their relation.
D000293:Adolescent; D000328:Adult; D000368:Aged; D003920:Diabetes Mellitus / Q000201:enzymology* / Q000628:therapy; D004734:Energy Metabolism; D004789:Enzyme Activation; D004912:Erythrocytes / Q000201:enzymology*; D005954:Glucosephosphate Dehydrogenase / Q000097:blood*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008875:Middle Aged
D007770:L-Lactate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase
Aktivnost' laktatdegidrogenazy i gliukozo-6-fosfatdegidrogenazy v éritrotsitakh pri sakharnom diabete