[Paraneoplasic Cushing' syndrome. Neurosecretory granules in a lymph node metastasis in electronic microscopy (author's transl) (proceedings)].
The authors relate a case of paraneoplasic Cushing's syndrome by mediastinal tumor, probably of thymic origin. All the clinical and biological signs recall similar cases previously related. An "ACTH-like" substance has been found by biological method in a lymphoide metastasis. The main interest resides in the anatomo-pathological findings and more especially in electronic microscopy. The abundance of the neurosecretory granules is a characteristic feature of the malignant cells observed. These granules appear to the authors identical to those observed in other secretory thymomas and various tumors.
D000328:Adult; D003480:Cushing Syndrome / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D008198:Lymph Nodes / Q000503:physiopathology / Q000648:ultrastructure; D008223:Lymphoma / Q000150:complications / Q000503:physiopathology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron
Syndrome de Cushing paranéoplasique. Granules d'aspect secrétoire au sein d'un ganglion métastasique, en microscopie électronique