[Action of thermal injury on the half-life time and turnover of cytoplasmic RNA in the intact tissues of rats].
In liver tissue, kidney, spleen and sceletal muscle of intact rats and animals, subjected to thermic burns of skin of the IIIa-IIIb degree, half-life and turnover of ribosomal and transport RNA were studied. In control animals half-life of ribosomal RNA was 5.1 days in liver tissue, 6.5 days in kidney, 6.7 days in spleen and 12.4 days in sceletal muscle. The same pattern for transport RNA was equal to 5.8, 4.7, 6.7, and 5.9 days, respectively. The burning trauma caused the alteration in turnover of cytoplasmic RNA; the direction and the intensity of the turnover had an organospecifics type and depended upon the period of the burning impairment.
D000818:Animals; D002056:Burns / Q000378:metabolism*; D002250:Carbon Radioisotopes; D003593:Cytoplasm / Q000378:metabolism*; D006207:Half-Life; D007668:Kidney / Q000166:cytology / Q000378:metabolism; D008099:Liver / Q000166:cytology / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000166:cytology / Q000378:metabolism; D012313:RNA / Q000378:metabolism*; D012335:RNA, Ribosomal / Q000378:metabolism; D012343:RNA, Transfer / Q000378:metabolism; D051381:Rats; D013154:Spleen / Q000166:cytology / Q000378:metabolism; D013997:Time Factors
D002250:Carbon Radioisotopes; D012335:RNA, Ribosomal; D012313:RNA; D012343:RNA, Transfer
Vozdeĭstvie termicheskoĭ travmy na vremia poluzhizni i oborot tsitoplazmaticheskikh RNK v nekotorykh intaktnykh tkaniakh u krys