title: [Membrane effect of potassium rhodanide and methotrexate].
abstract: In HeLa cells and macrophages rhodanide ions cause biological hyperpolarization of the cell membranes, while methotrexate hyperpolarizes the membranes as an antimetabolite. Cell physiologically, rhodanide has a general stimulating effect within the physiological control range of the cell. This membrane effect could be related to the physiological and therapeutic action of rhodanide in processes involving immunological events.
mesh_terms: D000818:Animals; D002417:Cattle; D002462:Cell Membrane / Q000187:drug effects*; D006168:Guinea Pigs; D006367:HeLa Cells / Q000187:drug effects; D008264:Macrophages / Q000187:drug effects; D008564:Membrane Potentials / Q000187:drug effects; D008727:Methotrexate / Q000494:pharmacology*; D013861:Thiocyanates / Q000494:pharmacology*
chemical_list: D013861:Thiocyanates; D008727:Methotrexate
vernacular_title: Zum Membraneffekt von Kaliumrhodanid und Methotrexat