Electron microscopic autoradiography of serotonin uptake in the ganglia of the fresh-water mussel (Anodonta cygneak L.).
After in vitro incubation, the uptake of labelled serotonin was investigated by electron microscopic autoradiography in the ganglia of fresh-water mussel (Anodonta cygnea L.) The labelled serotonin was primarily taken up by the axons of the neurons. The silver grains could always be localized over axons containing eccentric dense-core vesicles with a diameter of 100--200 nm. The results suggest (a) the possibility of the electron microscopic identification of serotonin-containing neurons, and (b) the direct role of the eccentric dense-core vesicles in the storage of serotonin.
D000818:Animals; D001345:Autoradiography; D001369:Axons; D049872:Bivalvia / Q000378:metabolism*; D003593:Cytoplasm; D005618:Fresh Water; D005724:Ganglia / Q000378:metabolism*; D008854:Microscopy, Electron