Effect of hexachlorophene on the coagulation process in beagle dogs.
In a dermal toxicological study the effect of hexachlorophene on the blood coagulation process in dogs over a period of 12 weeks was investigated. The thrombelastographic results revealed a reduction in reaction time, coagulation time and an increase in maximal amplitude supplemented with subsequent increase in the number of platelets and the enhancement of ESR.
D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D001799:Blood Sedimentation; D004285:Dogs; D005260:Female; D006582:Hexachlorophene / Q000633:toxicity*; D008297:Male; D013916:Thrombelastography
D006582:Hexachlorophene