title: Purification of interferon by adsorption chromatography on controlled pore glass.
abstract: Human fibroblast and mouse L929 cell interferons can be purified by adsoprtion to and subsequent elution from Controlled Pore Glass. Purification of 40 to 90-fold to specific activities of 1 to 5 times 10(6) units/mg of protein can be achieved in a single step, with good recovery of activity. Human leukocyte interferon does not bind to the glass and cannot be purified in this way.
mesh_terms: D002845:Chromatography; D005898:Glass; D007372:Interferons / Q000302:isolation & purification*; D007962:Leukocytes; D008722:Methods
chemical_list: D007372:Interferons