title: Metabolism of the gastrointestinal peptide hormones.
abstract: Results of investigations on the metabolism of gastrin, pentagastrin, cholecystokinin and secretin are discussed on the basis of data in the literature. Own results concerning the metabolism of 14C-pentagastrin are also described, out of which the significance of a biologically inactive metabolite is emphasized. This metabolite can be demonstrated in the circulation, and is excreted in the urine. As judged from the present state of investigations, this metabolite has a crucial importance in the metabolism of pentagastrin.
mesh_terms: D000818:Animals; D002766:Cholecystokinin / Q000378:metabolism; D004285:Dogs; D005755:Gastrins / Q000378:metabolism; D005768:Gastrointestinal Hormones / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D010418:Pentagastrin / Q000097:blood / Q000378:metabolism / Q000652:urine; D051381:Rats; D012633:Secretin / Q000378:metabolism
chemical_list: D005755:Gastrins; D005768:Gastrointestinal Hormones; D012633:Secretin; D002766:Cholecystokinin; D010418:Pentagastrin