The effect of ethyl apovincaminate on the circulation of the eyeground.
Ethyl apovincaminate (RGH-4405, Cavinton), contrary to the active vasodilators used up to the present, increases blood pressure of the eyeground. Dynamics of the eyeground circulation has been investigated with fluorescein angiography performed at certain points of time. Blood supply of the macula lutea was increased in the first place by Cavinton.
D001794:Blood Pressure / Q000187:drug effects; D005451:Fluorescein Angiography; D006801:Humans; D012039:Regional Blood Flow / Q000187:drug effects; D012164:Retinal Diseases / Q000188:drug therapy / Q000503:physiopathology; D012171:Retinal Vessels / Q000187:drug effects*; D014748:Vinca Alkaloids / Q000494:pharmacology*
D014748:Vinca Alkaloids