[Synthesis and Quaternation of Pyridine-aldoxim Alkylethers (author's transl)].
Using known procedures, alkylethers of pyridine-aldoxime not described as yet were prepared and transformed into pyridinium salts. The application of a solution of a,a'-di-iodo-dimethyl-ether proved especially useful in the synthesis of bisquarternary salts with formaldehyde-acetal bridge. All the new substances are ineffective in a paraoxon poisoning. On the other hand, some salts show protective action in soman intoxication.
D000818:Animals; D000931:Antidotes; D055598:Chemical Phenomena; D002621:Chemistry; D005260:Female; D051379:Mice; D010091:Oximes / Q000138:chemical synthesis*; D010261:Paraoxon / Q000506:poisoning; D012999:Soman / Q000506:poisoning
D000931:Antidotes; D010091:Oximes; D012999:Soman; D010261:Paraoxon
Darstellung und Quaternierung von Pyridinaldoxim-alkyläthern