title: Influence of hypoxia and hyperoxia on subcutaneous adipose tissue blood flow in man.
abstract: Subcutaneous adipose tissue blood flow (ATBF) was measured by the 133Xe washout method in normal men breathing oxygen at partial pressures from 0.1 to 2 atmospheres. Breathing oxygen at partial pressures of 0.1 and 1 atm. increased and reduced ATBF by 56% and 26%, respectively as compared to air breathing. These effects were highly significant. Breathing of oxygen at 2 atm. partial pressure had no consistent effect on ATBF, although considerable changes--positive or negative--could been seen in some experiments. Oxygen-breathing at 1 atm. partial pressure is associated with a slight hyperventilation and fall in PACO2. This was shown to be without importance for the effect of oxygen on adipose tissue blood flow.
mesh_terms: D000273:Adipose Tissue / Q000098:blood supply*; D000328:Adult; D002245:Carbon Dioxide / Q000378:metabolism; D006801:Humans; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D010100:Oxygen; D010313:Partial Pressure; D011650:Pulmonary Alveoli / Q000378:metabolism; D012039:Regional Blood Flow; D012119:Respiration
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen