[Comparative evaluation of the methods of determination of the orientation reaction of rats in a toxicological experiment].
A procedure for determining orientation reaction after Boissié et al (1964) was modified for albino rats. In determining the thresholds of acute action of phthalates and carboran in comparison with summation-threshold index, registration of spontaneous motor activity and orientation reaction according to the number of risings in a jar the proposed method is shown to be 5-10 times more sensitive.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D003993:Dibutyl Phthalate / Q000494:pharmacology; D004051:Diethylhexyl Phthalate / Q000494:pharmacology; D009043:Motor Activity / Q000187:drug effects*; D009949:Orientation / Q000187:drug effects*; D011581:Psychological Tests / Q000379:methods; D051381:Rats
D003993:Dibutyl Phthalate; D004051:Diethylhexyl Phthalate
Sravnitel'naia otsenka metodov opredeleniia orientirovochnoĭ reaktsii krys v toksikologicheskom eksperimente.