[Use of lophenal in patients with malignant ovarian tumors].
The use of lophenal in complex treatment of 27 patients with malignant ovarian tumors has shown that the substance possesses a definite antitumor activity, manifested in gaining the clinical effect in 60.9% of patients with an average duration of remission lasting for 5.3 months. The toxic effect on hemopoiesis as well as the side effect of the substance were liquidated by pharmacological drugs. It is concluded that lophenal should be used along with other chemotherapeutic drugs for treatment of patients with malignant ovarian tumors.
D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009588:Nitrogen Mustard Compounds / Q000008:administration & dosage / Q000627:therapeutic use*; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D010649:Phenylalanine / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use
D000970:Antineoplastic Agents; D009588:Nitrogen Mustard Compounds; D010649:Phenylalanine
Primenenie lofenala u bol'nykh zlokachestvennymi opukholiami iaichnikov