CPK isoenzymes in evaluation of myocardial ischemic injury.
Enzymatic criteria for diagnosis of myocardial infarction have suffered from a lack of specificity, since enzyme elevations also occur in noncardiac disorders. The MB isoenzyme of creatine phosphokinase has provided a way out of this difficulty. Not only is it specific to injured myocardium but a recently developed plasma assay makes possible both diagnosis and, in many cases, measurement of the extent of damage.
D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood* / Q000378:metabolism; D003937:Diagnosis, Differential; D006801:Humans; D007527:Isoenzymes / Q000097:blood* / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008722:Methods; D009203:Myocardial Infarction / Q000175:diagnosis*; D009206:Myocardium / Q000201:enzymology; D011379:Prognosis
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase