[Morphologic characteristics of carbon tetrachloride poisoned liver in the presence of iron loading].
The author examined the influence of abnormal amounts of iron on the development of early fibrosis (14th day), early and advanced cirrhosis (45th and 90th day) in liver esperimentaly damaged by carbon tetrachloride by means of morphological and histochemical methods. On the basis of the obtained data she could suggest that while at early stages iron did not have significant influence on the rate of development and gravity of the pathologic process, later (advanced cirrhosis) the changes were less manifested. She asumed that three valence iron, administered in the organism of the animals intoxicated by carbon tetrachloride, improved the course of the metabolic processes in the damaged liver cells, a manifestation of which was later and weaker development of the cirrhotic process.
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D007501:Iron / Q000627:therapeutic use*; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000209:etiology; D051381:Rats
D007501:Iron
Morfologichna kharakteristika na uvreden s tetrakhlormetan cheren drob pri natovarvane s zheliazo