Ovarian dysgerminoma, investigations on cell-and humoral-mediated immunologic reactions.
A 17-year-old girl with repeated ovarian dysgerminoma is described. Postoperative immunologic investigations prior to irradiation showed a transient increased cell--an humoral--mediated immunologic responsiveness of the patient for approximately 2 1/2 months. After irradiation, a markedly defective response to PHA was observed which improved when reexamined 11 months later. The patient is well 22 months after the second operation.
D000293:Adolescent; D004407:Dysgerminoma / Q000276:immunology* / Q000601:surgery; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000528:radiation effects; D007957:Leukocyte Adherence Inhibition Test; D010051:Ovarian Neoplasms / Q000276:immunology* / Q000601:surgery; D011183:Postoperative Complications / Q000532:radiotherapy