[Growth of eye and orbit in chick embryo. IX. Developement of eye and skull origin in 3-9 day old embryos with experimental bilateral microphthalmia].
Chick embryos in which on the third day of incubation the lens of both eye primordia was removed, were sacrificed at the ages of 5,7 and 9 days and fixed in a 70 per cent alcohol solution. An analysis was made of the consequences of the absence of normal large eyes upon the structure and growth of the skull. Immediately after the operation no changes in the head mesenchyme could be observed, but during the next days, as growth goes on, abnormal proportions and dimensions develop in the anterior part of the skull. Generally, this part of the skull is depressed and shorter than normal; cartilages around the eye have a different position and smaller dimensions. A perfect symmetry is only rarely maintained. There seems to be a very labile balance in the skull, as may be deduced from the presence of a buckled interorbital septum and the deviation of the upper beak.
D000818:Animals; D002642:Chick Embryo; D005123:Eye / Q000196:embryology*; D007908:Lens, Crystalline / Q000502:physiology; D008850:Microphthalmos / Q000503:physiopathology*; D009915:Orbit / Q000196:embryology*; D012886:Skull / Q000196:embryology*
Das Wachstum von Augen und Augenhöhlen beim Hühnerembryo. IX. Die Entwichklung der Augen- und Schädelanlage bei Embryonen von 3-9 Tagen mit künslich erzeugter doppelseitiger Mikrophthalamie