title: Generalized granuloma anulare in a 15-month-old infant.
abstract: A Japanese girl aged 15 months had an eruption of 3 months' duration on the face, trunk, and extremities except for the palms and soles. The lesions were infiltrated papules varying from 2 to 3 mm in diameter. Blood eosinophilia of 5% was demonstrated. Skin biopsy specimen revealed a necrobiotic palisading granuloma in the corium. All lesions began to subside after 1 weeks' administration of oral corticosteroid and completely involuted in 2 months. A possible etiologic role of insect bites was considered.
mesh_terms: D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006099:Granuloma / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007223:Infant; D012871:Skin Diseases / Q000188:drug therapy / Q000473:pathology
chemical_list: D000305:Adrenal Cortex Hormones