[Circulation time of 125I-labeled fibrinogen in patients with ischemic heart disease with different types of hyperlipoproteinemia].
In 31 patients with ischaemic heart disease and different types of hyperlipoproteinemia the Takeda method was used for determining the duration of 125I-labelled fibrinogen circulation. The half-life period of labelled fibrinogen was found to be twice shorter in the patients than in the normal individuals. Two types of curves of plasma radioactivity reduction were distinguished in patients with ischaemic heart disease. The briefest circulataion period of the labelled fibrinogen was found in patients with type II hyperlioproteinemia. In patients with ischaemic heart disease and normal blood lipids content the period of circulation of the labelled fibrinogen comprised 2.07 +/- 0.27 days and was higher than in those with hyperlipoproteinemia.
D000328:Adult; D000368:Aged; D001777:Blood Coagulation; D003327:Coronary Disease / Q000097:blood* / Q000150:complications / Q000209:etiology; D005260:Female; D005340:Fibrinogen / Q000378:metabolism*; D006207:Half-Life; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood* / Q000150:complications; D007457:Iodine Radioisotopes; D007553:Isotope Labeling; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D007457:Iodine Radioisotopes; D005340:Fibrinogen
Vremia tsirkuliatdii fibrinogena, mechennogo 125I u bol'nykh ishemicheskoĭ bolizn'iu serdtsa s razlichnymi tipami giperlipoproteidemiĭ