First experience with a new analgesic drug: buprenorphine.
Buprenorphine, a new analgesic drug, was used for treatment of immediate postoperative pain in a group of 30 patients. A standard dose of 4 mug/kg was given IM. Onset of action occurred 10 to 20 min. later; pain relief was very good to good in 73%, fairly good in 23% and insufficient in 3%. Duration of action was very long (Mean + SEM: 360 +/- 32 min.) Side effects were few.
D000368:Aged; D000700:Analgesics / Q000627:therapeutic use*; D055598:Chemical Phenomena; D002621:Chemistry; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009019:Morphinans / Q000627:therapeutic use*; D010149:Postoperative Pain / Q000188:drug therapy*; D013997:Time Factors
D000700:Analgesics; D009019:Morphinans