title: [Thrombolytic activity of terrilytin and its effect on the coagulating system of the blood].
abstract: The preliminary incubation of fibrinogen with terrilytin in vitro delayed the formation of the clot and accelerated the subsequent lysis. Terrylitin (in vitro) prolonged the recalcification time, lowered the thromboplastic  activity and that of fibrinase, and also enhanced the fibrinolytic activity of the blood plasma. In experiments on dogs roentgenovasography revealed a considerable thrombolytic activity of terrilytin following its intravenous infusion to the animals with experimental thrombosis of the femoral veins.
mesh_terms: D000681:Amylases / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D004285:Dogs; D004338:Drug Combinations; D004347:Drug Interactions; D005268:Femoral Vein; D005337:Fibrin / Q000494:pharmacology; D005340:Fibrinogen / Q000494:pharmacology; D005342:Fibrinolysis / Q000187:drug effects*; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D066298:In Vitro Techniques; D010447:Peptide Hydrolases / Q000008:administration & dosage / Q000494:pharmacology*; D010710:Phosphates / Q000008:administration & dosage / Q000494:pharmacology; D013927:Thrombosis / Q000188:drug therapy
chemical_list: D004338:Drug Combinations; D005343:Fibrinolytic Agents; D010710:Phosphates; C009402:amylase, phosphates, proteases drug combinations; D005337:Fibrin; D005340:Fibrinogen; D000681:Amylases; D010447:Peptide Hydrolases
vernacular_title: O tromboliticheskoi aktivnosti terrilitina i ego vliianii na svertyvaiushchuiu sistemu krovi