Lactate oxidation by skeletal muscle during sustained contraction in vivo.
Estimation of lactate oxidation in vivo was carried out by a tracer technique in the muscles of the lower hindleg of the dog during tetani of different duration. The fractional (%) rate of lactate oxidation increased markedly, compared with that of the resting muscle, after the first 2 min of stimulation. Lactate oxidation afforded a large contribution to the total oxygen consumption. Fatigue appeared to play a role in limiting lactate oxidation in the later phase of sustained contraction.
D000818:Animals; D004285:Dogs; D005221:Fatigue; D007773:Lactates / Q000378:metabolism*; D009119:Muscle Contraction; D009132:Muscles / Q000378:metabolism*; D010084:Oxidation-Reduction; D010101:Oxygen Consumption
D007773:Lactates