Evidence of diurnal fluctuation of sensitivity to noradrenaline in the rat-the role of the thyroid.
The capacity for heat production, under the influence of the same amount of noradrenaline, in the rat was significantly higher in the evening (20.00 h) than in the morning (07.00 h). Thyroidectomy produces not only a lower level of heat production, but also a complete disappearance of the differences between the morning and the evening experiments.
D000818:Animals; D001833:Body Temperature Regulation / Q000187:drug effects*; D002940:Circadian Rhythm; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology*; D010101:Oxygen Consumption / Q000187:drug effects*; D051381:Rats; D013961:Thyroid Gland / Q000502:physiology*
D009638:Norepinephrine