Occult sclerosing carcinoma of the thyroid.
A case of occult sclerosing thyroid carcinoma is reported. The primary requirement for diagnosis is that the cancer is less than 1.5 cm in diameter. In addition, a fibrosing component with varying degrees of sclerosis is present. Lymph node metastases are frequent and may appear as benign thyroid follicles. Occasional direct invasion or vascular invasion may occur. Distant metastases were not reported in the series reviewed. Adequate therapy would seem to be total thyroidectomy of the involved lobe and radical subtotal thyroidectomy of the opposite lobe with excision of all enlarged or involved lymph nodes.
D000230:Adenocarcinoma / Q000473:pathology*; D006044:Goiter, Nodular / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012598:Sclerosis; D013961:Thyroid Gland / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology*; D013965:Thyroidectomy