Time lapse cinematographic demonstration of humoral and cell mediated immunity in squamous cell carcinoma of the lung.
Out of 42 attempts in one case a cell line derived from biopsy material of a squamous cell carcinoma of the lung has been established. Tumor-associated-antigen could be demonstrated by indreict immunofluorescence. The effect of allogeneic cytotoxic antibodies, absorbed with normal human lung and sera, on the target cells is shown. Blood lymphocytes obtained from patients with squamous cell carcinoma of the lung proved to be cytotoxic against this cell line. The cell to cell interactions of this phenomenon and the effect of cytotoxic antibodies are shown by time lapse cinematography.
D000917:Antibody Formation; D000951:Antigens, Neoplasm; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D008175:Lung Neoplasms / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D009040:Motion Pictures
D000951:Antigens, Neoplasm