Metastases from single as compared to repeated tumour cell doses.
Tumour formation from single or repeated small i.v. tumour cell doses was studied in a syngeneic tumour-host system. Only marginal differences were observed between different dose schedules, once the critical cell dose level was surpassed.
D000818:Animals; D007275:Injections, Intravenous; D008175:Lung Neoplasms / Q000453:epidemiology; D051379:Mice; D008808:Mice, Inbred CBA; D009362:Neoplasm Metastasis / Q000453:epidemiology; D009368:Neoplasm Transplantation / Q000379:methods*; D012513:Sarcoma, Experimental / Q000453:epidemiology