[Combined treatment of Parkinsonism with levopa, midantan and anticholinergic drugs].
For the treatment of 42 patients with different forms of atherosclerotic and postencephalitic parkinsonism the author used levopa drugs, medantane, cyclodol and parkopan in combination and separately. The most stable improvement was obtained from a combination of levopa with cyclodol in patient with rigid-akynetic-trembling manifestations of parkinsonism. The treatment by medantane increased the therapeutical effect in the patients with postencephalitic parkinsonism. Methyl-dopa and pyridoxine served as a corrector of levopa. The studies on the blood content of acetylcholine and cholinesterase showed a growth of cholinolytic and cholinesterase activity in the blood.
D000109:Acetylcholine / Q000097:blood; D000328:Adult; D000368:Aged; D000547:Amantadine / Q000008:administration & dosage; D000978:Antiparkinson Agents / Q000008:administration & dosage*; D002802:Cholinesterases / Q000097:blood; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000150:complications; D007980:Levodopa / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009129:Muscle Tonus; D010300:Parkinson Disease / Q000097:blood / Q000188:drug therapy*; D010301:Parkinson Disease, Postencephalitic / Q000188:drug therapy; D010302:Parkinson Disease, Secondary / Q000188:drug therapy; D014282:Trihexyphenidyl / Q000008:administration & dosage
D000978:Antiparkinson Agents; D007980:Levodopa; D014282:Trihexyphenidyl; D000547:Amantadine; D002802:Cholinesterases; D000109:Acetylcholine
O kombinirovannom lechenii bol'nykh parkinsonizmom preparatami levopa, midantanom i antikholinergicheskimi sredstvami