title: [Experiences with sodium fluoride in the treatment of osteoporosis].
abstract: In 10 patients with primary and 13 patients with glucocorticoid osteoporosis a NaF-therapy with an average daily dose of 80 mg was carried out in a period of 1/2 to 4 1/2 years. 22 patients spoke about an improvement of the complaints. Radiologically an osteogenesis could be proved in 19 patients. Dose and duration of the therapy as well as eventual additional treatments, frequency and severity of the side-effects are discussed and the indication for a NaF-medication are elaborated.
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging; D000469:Alkaline Phosphatase / Q000378:metabolism; D005260:Female; D005459:Fluorides / Q000627:therapeutic use*; D005938:Glucocorticoids / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010012:Osteogenesis / Q000187:drug effects; D010024:Osteoporosis / Q000139:chemically induced / Q000188:drug therapy*; D011859:Radiography; D012969:Sodium Fluoride / Q000627:therapeutic use*; D013131:Spine / Q000000981:diagnostic imaging
chemical_list: D005938:Glucocorticoids; D012969:Sodium Fluoride; D000469:Alkaline Phosphatase; D005459:Fluorides
vernacular_title: Erfahrungen mit Natriumfluorid in der Behandlung der Osteoporose