Characterization of the biochemical mechanism of action of alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazones.
D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology*; D004273:DNA, Neoplasm / Q000096:biosynthesis; D003854:Deoxyribonucleotides / Q000096:biosynthesis; D066298:In Vitro Techniques; D007501:Iron / Q000494:pharmacology; D007700:Kinetics; D051379:Mice; D012262:Ribonucleoside Diphosphate Reductase / Q000037:antagonists & inhibitors; D012510:Sarcoma 180 / Q000378:metabolism; D013882:Thiosemicarbazones / Q000494:pharmacology*; D013936:Thymidine / Q000378:metabolism
D000964:Antimetabolites, Antineoplastic; D004273:DNA, Neoplasm; D003854:Deoxyribonucleotides; D013882:Thiosemicarbazones; D007501:Iron; D012262:Ribonucleoside Diphosphate Reductase; D013936:Thymidine