Effect of TSH and melatonin on thyroid activity in the rat.
Melatonin and TSH, injected separately, caused no change of the blood thyroxine level at 30 min after treatment. Simultaneous or subsequent administration of the two hormones induced an increase of the level. Thus, melatonin is capable of potentiating acute, thyroxine mobilizing effect of TSH.
D000818:Animals; D004357:Drug Synergism; D008550:Melatonin / Q000494:pharmacology*; D051381:Rats; D013961:Thyroid Gland / Q000187:drug effects*; D013972:Thyrotropin / Q000494:pharmacology*; D013974:Thyroxine / Q000097:blood*
D013972:Thyrotropin; D008550:Melatonin; D013974:Thyroxine