[Combined use of estradiol and insulin in experimental diabetes].
Experiments demonstrated that in diabetes subject to inhibition are the processes of respiration and phosphorylation and that estradiol-dipropionate in dose of 50 gamma/kg did not change significantly either utilization of oxygen, or attended by it phosphorylation in the uterus and liver, while in a dose of 100 gamma/kg it contributed to the combination of the respiratory and phosphorylation processes in the liver alone. Joint administration of insulin and estradiol restored nearly to the initial level the rate of the oxygen consumption and esterification of inorganic phosphorus in the uterus and liver.
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D004958:Estradiol / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D007328:Insulin / Q000008:administration & dosage* / Q000494:pharmacology; D008099:Liver / Q000378:metabolism; D010085:Oxidative Phosphorylation / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects; D010758:Phosphorus / Q000378:metabolism; D051381:Rats; D013268:Stimulation, Chemical; D014599:Uterus / Q000378:metabolism
D007328:Insulin; D010758:Phosphorus; D004958:Estradiol
K voprosu o sovmestnom primenenii estradiola i insulina pri eksperimental'nom diabete