title: [Thromboses and haemorrhages in geriatrics (author's transl)].
abstract: In elderly patients thromboses are especially important because of their frequency and consequences (invalidity) often demanding measures of rehabilitation. In thrombophilia there are prophylactic measures necessary founding upon new perceptions on pathogenesis (vascular wall factors; rheologic and microcirculatory factors and factors of hemostasis: increasing of factor VIII; decreasing of antithrombin III; hypofibrinolysis; increased aggregation of thrombocytes). In prophylaxis you should influence the predisposing factors (hypertension, diabetes, arteriosclerosis, adipositas), use dietetic and hygienic measures and also from the pharmalogical point medicines with complex effect, which not only act on one factor (blood coagulation) like the anticoagulants, but also on other pre-disposing factors; and at the same time activate the fibrinolysis and stop the aggregation of thrombocytes. Thrombolytica should be used in elderly patients with precaution. In hemorrhages in the age especially capillary protecting medicaments should be used to correct the increased fragility of capillaries. Of there is at the some time a arteriosclerosis, hypertension, diabetes mellitus, obesity.
mesh_terms: D000368:Aged; D000375:Aging; D001161:Arteriosclerosis / Q000150:complications; D001777:Blood Coagulation; D001792:Blood Platelets; D002449:Cell Aggregation; D003029:Coagulants / Q000627:therapeutic use; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006470:Hemorrhage / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D013927:Thrombosis / Q000150:complications / Q000188:drug therapy / Q000209:etiology
chemical_list: D003029:Coagulants; D005343:Fibrinolytic Agents
vernacular_title: Thrombosen und Blutungen in der Geriatrie