[Nature of tryptophan photooxidation products in lysozyme in the presence of methylene blue].
One out of six trytophan residues in two lysozyme modification, obtained under lysozyme photooxidation in the presence of methylene blue, is found to be oxidized to N'-formylkinurenine (in one modification) and to kinurenine (in the other modification). The transition of one modification into another via detaching of N'-formyl group by soft acid hydrolysis has shown that one and the same tryptophan residue is oxidized in both products, Possible mechanism of tryptophan oxidation to the products mentioned is discu-sed on the basis of the hypothesis on signlet mechanism of lysozyme photooxidation in the presence of methylene blue.
D002686:Chitin; D002846:Chromatography, Affinity; D006868:Hydrolysis; D007737:Kynurenine / Q000378:metabolism; D008751:Methylene Blue / Q000494:pharmacology; D008837:Micrococcus / Q000201:enzymology / Q000378:metabolism*; D009113:Muramidase / Q000032:analysis* / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism*; D010788:Photosynthesis; D013056:Spectrophotometry, Ultraviolet; D014364:Tryptophan / Q000378:metabolism*
D002686:Chitin; D007737:Kynurenine; D014364:Tryptophan; D009113:Muramidase; D010100:Oxygen; D008751:Methylene Blue
O kharatere produktov fotookisleniia triptofana v lizotsime v prisutstvii metilenovoĭ sini