Total and free testosterone and total and free 17 beta-oestradiol in normally menstruating women.
Estimations of plasma total and free testosterone (T) as well as of total and free 17beta-oestradiol (E2) have been performed in 6 normal women throughout the menstrual cycle. The plasma total T levels showed a small but significant cyclical variations, with significantly increased values around the midcycle (p less than 0.001). The pattern of free T during the cycle was similar to total T. Regarding total plasma E2, two typical peaks occurred, which were also observed in plasma free E2. Changes in testosterone-17beta-oestradiol binding globulin have not been detected throughout the menstrual cycle.
D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D008598:Menstruation; D012738:Sex Hormone-Binding Globulin / Q000032:analysis; D013739:Testosterone / Q000097:blood*
D012738:Sex Hormone-Binding Globulin; D013739:Testosterone; D004958:Estradiol