Blood glucose: how reliable an indicator of brain glucose?
It is usually assumed that the concentration of glucose in the brain reflects that in the blood, so that measuring the latter provides an accurate index of the former. However, in two experimental situations analogous to anoxia and salicylate poisoning, brain glucose was found to be dangerously low in the presence of normal or even elevated blood glucose levels, and in these experiments administering glucose prolonged survival.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry; D005947:Glucose / Q000032:analysis / Q000378:metabolism* / Q000627:therapeutic use; D006854:Hydrocortisone / Q000494:pharmacology; D000860:Hypoxia / Q000378:metabolism; D051379:Mice; D012459:Salicylates / Q000506:poisoning
D001786:Blood Glucose; D012459:Salicylates; D005947:Glucose; D006854:Hydrocortisone