title: [Local-anesthetic activity of l-aminoacetyl-2, 3-dihydroindole derivatives].
abstract: 1-(N-piperidine-acetyl)-2,3-dihydroindoles display high activity in infiltration and conduction anestheia, exceeding that of trimecaine. N-alkylaminoacetyl-indolines are moderately active, while N-morpholine and N-indolylacetyl-indolines are practically inactive when employed in the given types of local anesthesia. All the N-substituted aminoacetyl-indolines are little active in terminal anesthesia.
mesh_terms: D000779:Anesthetics, Local / Q000494:pharmacology*; D000818:Animals; D001001:Anura; D004341:Drug Evaluation; D006168:Guinea Pigs; D007211:Indoles / Q000494:pharmacology*; D051379:Mice; D009025:Morpholines / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D014288:Trimecaine / Q000494:pharmacology
chemical_list: D000779:Anesthetics, Local; D007211:Indoles; D009025:Morpholines; D014288:Trimecaine
vernacular_title: Mestnoanesteziruiushchaia aktivnost' proizvodnykh l-aminoatsetil-2,3-digidroindolov