[Endocrinotropic actions of the benzamide sultopride (author's transl)].
The influence on the pituitary hypothalamic system of Sultopride are different of those of a chemically related compound, Sulpiride. In the mammary gland the development of the acini is associated with an increase of the connective tissue. The processus of secretion, lactogenesis is quiet not stimulated. The changes on the anterior lobe of the pituitary involve the carmino and eosinophilic cells. This modification seems to reflect a stimulation of the secretion of LT and an inhibition of the release of STH. In the juvenile rat, Sultopride determines an inhibition of the somatic growth.
D000375:Aging; D000818:Animals; D005260:Female; D007031:Hypothalamus / Q000187:drug effects / Q000254:growth & development / Q000502:physiology*; D008297:Male; D008321:Mammary Glands, Animal / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure; D010902:Pituitary Gland / Q000187:drug effects* / Q000502:physiology*; D010903:Pituitary Gland, Anterior / Q000187:drug effects* / Q000254:growth & development / Q000502:physiology*; D051381:Rats; D013469:Sulpiride / Q000031:analogs & derivatives* / Q000494:pharmacology
D013469:Sulpiride
Propriétés endocrinotropes d'une benzamide, le sultopride