title: [Combined treatment for malignant primitive brain tumors in infants using CCNU, neurosurgery and radiotherapy (author's transl)].
abstract: The preliminary data (13 cases) is used to make a comparison between the survival length from the beginning of chemotherapy of these pediatric neuro-oncotypes with that of adults bearing sovra-tentorial astrocytomas or glioblastomas given the same treatment. Approximating, by means of normal distributions, the experimental results the Authors also note that the clinical efficacy of CCNU is more or less the same for infants and adults.
mesh_terms: D000367:Age Factors; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008722:Methods; D009607:Nitrosourea Compounds / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D009607:Nitrosourea Compounds
vernacular_title: Trattamento combinato con CCNU, intervento chirurigico e radiumterapia delle neoplasie endocraniche primitive dell'infanzia