Oscillations and cysteine metabolism in aortic strips of hypertensive rats.
Aortic strips of normal and hypertensive rats were used for the study. In comparison with normal rats hypertensive rats show a low cysteine and high homocysteine level and vascular auto-oscillations. The auto-oscillations are damped by cysteine, cAMP, theophylline and heparin but not by ADP.
D000818:Animals; D001013:Aorta, Thoracic; D001158:Arteries / Q000378:metabolism*; D001161:Arteriosclerosis / Q000378:metabolism; D003545:Cysteine / Q000378:metabolism*; D006973:Hypertension / Q000378:metabolism; D009119:Muscle Contraction; D009130:Muscle, Smooth / Q000502:physiology; D010507:Periodicity; D051381:Rats; D011919:Rats, Inbred Strains; D013438:Sulfhydryl Compounds / Q000378:metabolism
D013438:Sulfhydryl Compounds; D003545:Cysteine