Leukemia in twins: antenatal and postnatal factors.
Two factors emerged from a search for obstetric phenomena that might explain concordance of leukemia in both members of a twin pair within days or months of each other: antenatal exposure to ionizing radiation; and antenatal cojoined intrauterine circulation. In addition, antenatal tumor metastasis and chromosomal changes, antenatal or postnatal, may be contributory. Continued observation of reports should be carried out.
D000293:Adolescent; D000328:Adult; D001163:Arteriovenous Anastomosis; D002648:Child; D002675:Child, Preschool; D002904:Chromosomes, Human, 21-22 and Y; D004200:Diseases in Twins; D005260:Female; D006801:Humans; D007938:Leukemia / Q000196:embryology / Q000209:etiology* / Q000235:genetics; D007953:Leukemia, Radiation-Induced; D008297:Male; D009362:Neoplasm Metastasis; D010920:Placenta / Q000098:blood supply; D010922:Placenta Diseases; D011247:Pregnancy; D011859:Radiography / Q000009:adverse effects; D014430:Twins, Monozygotic