[Morphological characteristics of the myocardium of rabbits in experimental arteriosclerosis].
Histological, histochemical, and electron-microscopy studies of the myocardium of 70 rabbits were conducted; experimental atherosclerosis of the aorta in rabbits was caused by periodic four-fold fasting in combination with additions of crystal cholesterol to the diet. Along with the development of the ahterosclerofic process in the aorta, in the myocardium there were noted changes in the endothelium of capillaries, a more intensive production of acid polysaccharides by fibroblasts, a progressing development of the collagenous stroma, a higher heterogeneity of the contractile myocardium, and grave impairment of the structure and functions of the mypcardial cells (appearance of atrophying muscular cells with a decrease in the number of myofibrils) long before the onset of morphological changes in the coronary arteries.
D000818:Animals; D001018:Aortic Diseases / Q000473:pathology*; D001161:Arteriosclerosis / Q000473:pathology*; D002452:Cell Count; D005347:Fibroblasts / Q000378:metabolism; D008854:Microscopy, Electron; D009206:Myocardium / Q000473:pathology* / Q000648:ultrastructure; D009210:Myofibrils; D011134:Polysaccharides / Q000378:metabolism; D011817:Rabbits
D011134:Polysaccharides
Morfologicheskaia kharakteristika miokarda krolikov pri eksperimental'nom ateroskleroze