title: Design and methodology of the Zagreb preliminary study: response rates at the study stages.
abstract: A procedure for recruitment of a trial cohort from a demographically defined population is described. Provision was made by means of a prescreening survey to determine demographic and attitudinal characteristics in the group invited to screening before the invitation was extended, thus providing information on non-participants as well as participants. Men who satisfied the criteria for borderline levels of one or more of the three risk factors on at least two of possible three occasions were invited to participate in a radomized multifactor treatment trial either being treated by medication for the appropriate risk factor [or factors], or observed during the same intervals in the same fashion as those treated. During follow-up attempts were made to measure adherence to the prescribed medication.
mesh_terms: D002318:Cardiovascular Diseases / Q000517:prevention & control*; D003920:Diabetes Mellitus / Q000188:drug therapy; D005500:Follow-Up Studies; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy; D006973:Hypertension / Q000188:drug therapy; D008297:Male; D008620:Meprobamate / Q000008:administration & dosage; D008875:Middle Aged; D010349:Patient Compliance; D011159:Population Surveillance; D012110:Reserpine / Q000008:administration & dosage; D012306:Risk; D015022:Yugoslavia
chemical_list: D012110:Reserpine; D008620:Meprobamate