[Several biochemical signs of loss and restoration of visual function].
With the aid of cytophotometry the author studied the cellular chemistry of neurons (according to the activity of glutamate dehydrogenase) in the III, IV and V layers of the visual cortex in rats during the period of rehabilitation of specific functions following long-term light deprivation. It was demonstrated that a 2-week stay of deprivated animals in conditions of usual light is accompanied by visible normalization of the glutamate dehydrogenase activity in the cortical neurons. However, a complete rehabilitation of the control level was not attained. The study demonstrated differences in the reactions of identical neurons in the IV and V layers to the rehabilitation of specific functions. It is being assumed that the rehabilitation of the visual function may be due to biochemical reconstructions in the monomodel and certain parts of the polymodal neurons in the visual cortex.
D000818:Animals; D001931:Brain Mapping; D005969:Glutamate Dehydrogenase / Q000378:metabolism*; D009430:Neural Analyzers / Q000201:enzymology; D051381:Rats; D012683:Sensory Deprivation; D014785:Vision, Ocular; D014793:Visual Cortex / Q000201:enzymology*
D005969:Glutamate Dehydrogenase
O nekotorykh biokhimicheskikh priznakakh utraty i vosstanovleniia zritel'noĭ funktsii