[A new fluorometric method for the determination of drugs in biological material (author's transl)].
A description is given of a new method for fluorometric determination of drugs in biological material. The assay is based on photochemical transformation of non-fluorescent compounds in fluorophors by short-wave UV light. The pharmacokinetics of the 2-[4-(4'-chlorophenoxy)-phenoxy]-propionic acid (HCG 004) serves as an example to demonstrate the usefulness of this method; reference is also made to analogously successful studies of other drugs.
D000818:Animals; D004285:Dogs; D007700:Kinetics; D008297:Male; D010215:Papio; D004364:Pharmaceutical Preparations / Q000032:analysis*; D010647:Phenyl Ethers / Q000097:blood; D010777:Photochemistry; D011422:Propionates / Q000097:blood; D051381:Rats; D013050:Spectrometry, Fluorescence / Q000379:methods*; D013552:Swine; D014466:Ultraviolet Rays
D004364:Pharmaceutical Preparations; D010647:Phenyl Ethers; D011422:Propionates
Eine neue fluorometrische Methode zur Bestimmung von Pharmaka in biologischem Material