title: [Alcohol infusion of the pituitary, high-dose medroxyprogesterone and their association as analgesics in advanced breast cancer (author's transl)].
abstract: The analgesic effects of alcohol infusion of the pituitary, high-dose progesterone and their association on chronic intractable pain in TxN+M+ breast cancer patients no longer responsive to combination chemotherapy, radiotherapy and hormone therapy are assessed. The antalgic effect of medroxyprogesterone proved to be more lasting than that of alcohol infusion of the pituitary. Moreover, 6 of the 20 patients treated with the former presented regression of the disease whereas none of those treated with alcohol did so.
mesh_terms: D000700:Analgesics / Q000008:administration & dosage; D001943:Breast Neoplasms / Q000188:drug therapy*; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008525:Medroxyprogesterone / Q000008:administration & dosage* / Q000627:therapeutic use; D008722:Methods; D010902:Pituitary Gland; D012658:Sella Turcica; D013997:Time Factors
chemical_list: D000700:Analgesics; D000431:Ethanol; D008525:Medroxyprogesterone
vernacular_title: Effetto antalgico dell'alcoolizzazione ipofisaria, del medrossi-progesterone acetato ad alte dosi e della loro associazione nel carcinoma mammario in fase avanzata