title: A profile for trimipramine.
abstract: A series of sixty-one patients with depressive symptoms were treated with trimipramine in single nightly dosages. Analysis of the data indicated that a favourable outcome was likely to be associated with the following features: absence of gastro-intestinal complaints; absence of hypochondriasis; a level of anxiety not more than the average for psychiatric patients; absence of situational palpitation; possession of a stable work record; and possession of a family history positive for psychiatric disorder. These features are not claimed to be specific to treatment with trimipramine. Age, sex, out-patient/in-patient status and the over-all degree of depression were not found to be relevant. Trimipramine was associated with a favourable outcome in 64% of all cases treated, and in 73% of primarily depressive conditions.
mesh_terms: D000328:Adult; D003201:Computers; D003863:Depression / Q000188:drug therapy*; D003984:Dibenzazepines / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013223:Statistics as Topic; D014299:Trimipramine / Q000627:therapeutic use*
chemical_list: D003984:Dibenzazepines; D014299:Trimipramine