title: [Effect of adaptation to altitude hypoxia in early ontogeny on the indices of higher nervous activity].
abstract: Newborn male and female Wistar rats were adapted to hypoxia in a pressure chamber. Adaptation was started from the "altitude" of 1000 m, 1 hour daily, and then the time and the intensity of hypoxic actions were gradually increased: beginning from the 17th day the animals were subjected to adaptation to the "altitude" of 5000 m, for 5 hours, 5 days a week. The defence conditioned reflex of active avoidance was provoked in the animals after 2-month adaptation. A tendency to a more rapid elaboration of the reflex and a markedly enhanced degree of its retention in comparison with control was revealed in the adapted males. No significant changes in the elaboration and rentention of the reflex were found in the female animals adapted to hypoxia under analogous conditions.
mesh_terms: D000222:Adaptation, Physiological; D000531:Altitude; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology; D001273:Atmosphere Exposure Chambers; D003214:Conditioning, Classical / Q000502:physiology; D004924:Escape Reaction / Q000502:physiology; D005260:Female; D006613:Higher Nervous Activity; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D051381:Rats; D013997:Time Factors
vernacular_title: Vliianie adaptatsii k vysotnoĭ gipoksii v rannem ontogeneze na pokazateli vyssheĭ nervnoĭ deiatel'nosti