title: [Changes in the cytochemical properties of chromatin after stimulating proliferation in a stationary culture of Chinese hamster cells].
abstract: The first part of the prereplicative period in stimulated for cell proliferation steady-state culture of Chinese hamster cells was studied cytochemically. Investigation of the binding pattern of basic dye Acridine orange and Actinomycin D with cell nuclei and the melting profile of chromatin in situ suggests that one of the early events occurring in the course of stimulation of cell proliferation in steady-state culture is chromatin activation, i.e. changes in its physicochemical properties resulting in augmentation of transcription.
mesh_terms: D000166:Acridines / Q000378:metabolism; D000818:Animals; D002460:Cell Line; D002843:Chromatin / Q000378:metabolism*; D006224:Cricetinae; D004247:DNA; D003609:Dactinomycin / Q000378:metabolism; D005557:Formaldehyde / Q000494:pharmacology; D006651:Histocytochemistry; D006358:Hot Temperature; D008297:Male; D008938:Mitosis; D009691:Nucleic Acid Denaturation; D013094:Spermatozoa / Q000378:metabolism
chemical_list: D000166:Acridines; D002843:Chromatin; D003609:Dactinomycin; D005557:Formaldehyde; D004247:DNA
vernacular_title: Izmenenie tsitokhimicheskikh svoĭstv khromatina pri stimulirovanii proliferatsii v statsionarnoĭ kul'ture kletok kitaĭskogo khomiachka