Ultrastructural and cytochemical localization of calcium in a rat cardiac muscle in normal and experimental conditions.
The experiment carried out by us on the, stimulated by adrenaline, cardiac muscle allowed the activation of calcium localized mainly in the mitochondria, MA and FA of the intercalated discs and SR to be translocated in the direction of the sarcomere myofilaments and this especially to the thin actin filaments. The authors' experimental proves, that during the contraction--relaxation function of the cardiac muscle there exists a circulation rythm or a oscillatory functional flow of calcium ions between the mitochondria, intercalated discs and SR and the contractile fibrillae of the sarcomere.
D000818:Animals; D002118:Calcium / Q000302:isolation & purification* / Q000378:metabolism; D004837:Epinephrine / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects*; D006352:Heart Ventricles; D008297:Male; D008931:Mitochondria, Muscle / Q000032:analysis; D009200:Myocardial Contraction; D009206:Myocardium / Q000378:metabolism / Q000648:ultrastructure*; D009210:Myofibrils / Q000032:analysis; D051381:Rats; D012519:Sarcoplasmic Reticulum / Q000032:analysis
D002118:Calcium; D004837:Epinephrine