[Reactions of the pulp-dentin system to drugs].
The healthy or previously damaged pulp responds to most of the drugs currently applied to the dentin with an inflammatory reaction. By means of a standardized biological screening test, the modes of action of hydrogen peroxide and of Falikain preparations are demonstrated on the pulp of the rat incisor. Hydrogen peroxide produces an emphysema of the pulp tissue associated with a slowing of the circulation and partly irreversible capillary stases, whereas Falicain compound preparations (Falicid, Myrex) cause, by way of haemolysis, injuries involving entire areas of the pulp. For this reason, hydrogen peroxide should not be used for cleaning cavities. Myrex is well suited for symptomatic treatment to relieve pain, if removal of the inflamed pulp ensues.
D003782:Dental Pulp / Q000187:drug effects*; D003804:Dentin / Q000187:drug effects*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D006861:Hydrogen Peroxide / Q000009:adverse effects*; D011343:Procaine / Q000009:adverse effects*
D011343:Procaine; D006861:Hydrogen Peroxide
Die Reaktionen des Pulpa=Dentin-Systems auf Medikamente