title: A histopathologic, histobacteriologic, and radiographic study of periapical endodontic surgical specimens.
abstract: Data available on 230 periapical endodontic surgical specimens were studied. It was found that bacteria occurred in the periapical tissue very infrequently. In addition, there was no correlation between the presence of acute inflammatory cells and the presence or absence of pain. Granulomas with epithelium occurred in 61 out of 230 cases, while 14 of these were cysts. Of the 110 cases with radiographic follow-up data, 67 were classified as successful, 40 were uncertain, and 3 were unsuccessful according to a modification of Strindberg's criteria, whereas 107 would have been successes according to the criteria of Bender and Seltzer and their associates. No valid biologic or clinical basis for endodontic therapy as suggested by Bhaskar was found in this material.
mesh_terms: D003238:Connective Tissue / Q000473:pathology; D003560:Cysts / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D006099:Granuloma / Q000473:pathology; D006801:Humans; D010486:Periapical Tissue / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D010510:Periodontal Diseases / Q000473:pathology; D010518:Periodontitis / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D011859:Radiography; D012390:Root Canal Therapy; D014092:Tooth Root / Q000601:surgery*