Effect of dietary supplementation of glycine on caries development and lipids in rat molars.
The effect of dietary supplementation of glycine at a level of 4% on caries development and the lipid content of rat molar teeth was studied. The glycine supplementation caused a 65.7% reduction in caries development and a 15.1% reduction in lipid content. In a concurrent balance study, it was noted that the dietary glycine did not have any significant effect on the retention of either calcium or phosphorus by the rat's body. Changes in the fatty acid composition of the tooth and a reduction in growth rate were noted, however.
D000818:Animals; D002136:Calcium, Dietary / Q000378:metabolism; D002327:Cariostatic Agents; D003731:Dental Caries / Q000378:metabolism*; D004037:Diet, Cariogenic; D005227:Fatty Acids / Q000032:analysis; D005260:Female; D005504:Food Analysis; D005527:Food, Fortified; D005998:Glycine / Q000494:pharmacology*; D008055:Lipids / Q000032:analysis*; D008297:Male; D008963:Molar / Q000032:analysis*; D010758:Phosphorus / Q000378:metabolism / Q000652:urine; D051381:Rats
D002136:Calcium, Dietary; D002327:Cariostatic Agents; D005227:Fatty Acids; D008055:Lipids; D010758:Phosphorus; D005998:Glycine