Surface-chemical studies on chlorhexidine and related compounds: II. Interactions with monomolecular-film systems.
Interactions of chlorhexidine and structurally related biguanides with selected monomolecular-film systems (that is, stearic acid, stearyl alcohol, and N-octadecylacetamide) were explored. The data reflected the significance of ionic associations between the compounds and stearic acid films and, in the instance of the biguanide analogs, indicated that the length of the alkyl chain was an important factor in the penetration process.
D000081:Acetamides / Q000378:metabolism; D000438:Alcohols / Q000378:metabolism; D001645:Biguanides / Q000378:metabolism; D011312:Pressure; D013229:Stearic Acids / Q000378:metabolism; D013329:Structure-Activity Relationship; D013499:Surface Properties; D013500:Surface Tension
D000081:Acetamides; D000438:Alcohols; D001645:Biguanides; D013229:Stearic Acids