title: Minimal requirements for template recognition by bacteriophage Qbeta replicase: approach to general RNA-dependent RNA synthesis.
abstract: Any oligo- or polynucleotide able to offer a C-C-C-sequence at the 3'-terminus and a second C-C-C-sequence in a defined steric position to Qbeta replicase is an efficient template. Corresponding chemical modifications convert non-template RNAs to template RNAs.
mesh_terms: D001483:Base Sequence; D003090:Coliphages / Q000201:enzymology*; D009690:Nucleic Acid Conformation; D009843:Oligoribonucleotides / Q000032:analysis; D011777:Q beta Replicase / Q000378:metabolism*; D012316:RNA Nucleotidyltransferases / Q000378:metabolism*; D012328:RNA Viruses / Q000201:enzymology; D012367:RNA, Viral / Q000096:biosynthesis; D012324:RNA-Dependent RNA Polymerase / Q000378:metabolism*; D013698:Templates, Genetic
chemical_list: D009843:Oligoribonucleotides; D012367:RNA, Viral; D011777:Q beta Replicase; D012316:RNA Nucleotidyltransferases; D012324:RNA-Dependent RNA Polymerase