[Acute lymphoblastic leukemia after tuberculosis in a 8-year old greek boy with homozygous beta-thalassemia (author's transl)].
A greek boy is described in whom pulmonary tuberculosis and homozygous beta-thalassemia was discovered at 4 years of age. Tuberculosis was cured after 1 year of combined tuberculostatic chemotherapy. His thalassemia only required 1-2 blood transfusions per year. Acute lymphoblastic leukemia was diagnosed in the patient at 8 years of age and treated with antileukemic combination chemotherapy and cranial irradiation. 7 months after diagnosis the boy is still in continuous complete remission under antileukemic chemotherapy without requiring blood transfusions.
D001803:Blood Transfusion; D002648:Child; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005860:Germany, West; D006115:Greece / Q000208:ethnology; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy; D008297:Male; D015122:Mercaptopurine / Q000627:therapeutic use; D008727:Methotrexate / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D012075:Remission, Spontaneous; D012886:Skull; D013789:Thalassemia / Q000150:complications* / Q000628:therapy; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000150:complications*; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine; D003520:Cyclophosphamide; D015122:Mercaptopurine; D011241:Prednisone; D008727:Methotrexate
Akute lymphoblastische Leukämie nach Tuberkulose bei einem 8jährigen Griechen mit homozygoter beta-Thalassämie