The intravenous infusion of co-trimoxazole in cases of septicaemia: tolerance and results of treatment.
The tolerance to co-trimoxazole given by intravenous infusion was investigated in 25 patients suspected to be suffering from septicaemia. One patients developed allergic skin manifestations and two had increased difficulties with cardiac insufficiency, probably on account of the infusion. The other patients tolerated well. The results of treatment of 11 patients with septicaemia were good in 8 cases. In 2 cases, the poor results of the treatment can be explained by the presence of undrained abscesses  in these patients. Good concentrations of the components in the serum were achieved by the treatment.
D000293:Adolescent; D000328:Adult; D000368:Aged; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D018805:Sepsis / Q000188:drug therapy*; D013420:Sulfamethoxazole / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D014295:Trimethoprim / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use
D004338:Drug Combinations; D014295:Trimethoprim; D013420:Sulfamethoxazole