title: [Neoplastic variant of acute erythroblastotis--proerythroblastoma].
abstract: In two case of aorthochromatic anaemia refractory to treatment with granulocytopenia and thrombocytopenia without significant enlargement of abdominal viscera a hypothesis of uncontrolled proliferation involving proerythroblasts is put forward on the basis of bone marrow findings. This proliferation seems to be confined to a single focus-bone marrow, without evidence of peripheral dissemination. Profound dysplastic changes of proerythroblasts are suggestive of neoplastic growth.
mesh_terms: D000208:Acute Disease; D000328:Adult; D001853:Bone Marrow / Q000201:enzymology / Q000473:pathology; D001854:Bone Marrow Cells; D004900:Erythroblasts / Q000473:pathology*; D004912:Erythrocytes / Q000473:pathology*; D005260:Female; D006801:Humans; D004915:Leukemia, Erythroblastic, Acute / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010544:Peroxidases / Q000378:metabolism
chemical_list: D010544:Peroxidases
vernacular_title: Nowotwór (?) wychodz, acy z wczesnych prekursorów erytronu--proerythroblastoma