Vascular lesion (arteriovenous aneurysm or haemangioma) of the orbit in a case of chronic granulomatous disease.
A case of arteriovenous aneurysm or congenital arteriovenous haemangioma of the orbit is described in a 5-year-old boy with chronic granulomatous disease. Lipid pigments are demonstrated in endothelial cells as well as in histiocytes and fibrocytes. There appears to be a decreased ability to remove phagocytosed haemosiderin, in addition to the well-known inability of granulocytes, and probably to some extent of histiocytes, to kill phagocytosed bacteria.
D001165:Arteriovenous Malformations / Q000150:complications* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005128:Eye Diseases / Q000150:complications / Q000473:pathology; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006391:Hemangioma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D009915:Orbit / Q000098:blood supply* / Q000473:pathology; D010585:Phagocyte Bactericidal Dysfunction / Q000150:complications*