Acute arthritis caused by Aeromonas hydrophola: clinical and therapeutic aspects.
Two cases of Aeromonas hydrophila arthritis are reported and a third case present in the literature is reviewed. All three cases occurred in patients with myelogenous leukemia; the knee joint was involved in 2 patients and the metacarpal-phalangeal joint in the third. In the 2 patients presented here, synovial fluid antibiotic levels were measured and were adequate; but A hydrophila was repeatedly cultured from the knee joints, a fact suggesting that other factors, such as normal functioning leukocytes and specific opsonizing antibody against the organism, are also necessary to kill A hydrophila.
D000208:Acute Disease; D000328:Adult; D000333:Aeromonas / Q000302:isolation & purification / Q000472:pathogenicity; D001170:Arthritis, Infectious / Q000209:etiology* / Q000382:microbiology; D004756:Enterobacteriaceae Infections; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000382:microbiology; D007951:Leukemia, Myeloid / Q000150:complications; D015470:Leukemia, Myeloid, Acute / Q000150:complications; D008297:Male