Rapid diaphyseal destruction. An unusual osseous manifestation of chronic granulocytic leukemia.
A patient with chronic granulocytic leukemia developed an unusual rapidly progressive mid-diaphyseal femoral lesion. Differentiating this myeloblastic lesion from other round cell tumors is most reliably done by a Wright-Giemsa stained touch preparation. Prompt palliative therapy with long bone stabilization permitted the patient to remain ambulatory until shortly before his death.
D000328:Adult; D001847:Bone Diseases / Q000209:etiology / Q000473:pathology; D005269:Femur / Q000473:pathology; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications* / Q000473:pathology; D008297:Male