Chromosome abnormalities identified by banding technique in a patient with acute myeloid leukaemia complicating Hodgkin's disease.
Chromosome analyses using the Giemsa banding technique were performed on bone marrow cells in a patient with the association of Hodgkin's disease and acute myeloid leukaemia. All cells had an abnormal karyotype showing an extra chromosome No. 14, loss of one chromosome No. 17 and gain of one chromosome No. 18. These abnormalities are in many respects similar to the karyotype changes of lymphoid cells in malignant lymphomas, suggesting a pathogenetic relationship between the two disorders.
D000328:Adult; D000782:Aneuploidy; D001854:Bone Marrow Cells; D002869:Chromosome Aberrations; D002901:Chromosomes, Human, 13-15; D002902:Chromosomes, Human, 16-18; D006689:Hodgkin Disease / Q000150:complications / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000235:genetics*; D008297:Male; D014314:Trisomy