title: [Malignant bone tumours in childhood (author's transl)].
abstract: Of the malignant bone tumors that occur in childhood, chondrosarcoma, osteosarcoma, and Ewing's sarcoma are of special interest with regard to therapeutic approach. Whereas in chondrosarcoma radical surgery is the treatment of choice, due to its resistance to radiation, the most efficient treatment for osteosarcoma and Ewing's sarcoma has not yet been clearly defined. In the light of recepnt developments, delayed surgery following initial radiation in osteosarcoma, as advocated by Cade in 1947, has now been superseded by immediate amputation. In Ewing's sarcoma, radiation appears to be superior to surgical intervention, according to recent publications.
mesh_terms: D000671:Amputation, Surgical; D001859:Bone Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D002648:Child; D002813:Chondrosarcoma / Q000601:surgery; D006801:Humans; D012516:Osteosarcoma / Q000601:surgery; D011379:Prognosis; D012512:Sarcoma, Ewing / Q000532:radiotherapy / Q000601:surgery
vernacular_title: Maligne Knochengeschwülste im Kindesalter