Spike-forming model of neural membrane: computer simulation of additional perfused axon experiments.
In this paper a physical model of the neural membrane that I developed is tested for its ability to account for the details of the action potential spikes observed in squid giant axons, when perfused with sodium- and potassium-free fluids and surrounded by a calcium chloride solution. The near-zero resting potential of these perfused axons is accounted for by the model. The sizes, shapes, and conductances of the spikes observed with a number of different perfusates are also accounted for, when suitable values are assigned to the so-far unmeasured membrane constants that control the model properties. The three papers comprising the series are summarized at the end of this paper.
D000200:Action Potentials; D001369:Axons / Q000378:metabolism / Q000502:physiology*; D002118:Calcium / Q000378:metabolism; D002794:Choline / Q000378:metabolism; D003201:Computers; D004553:Electric Conductivity; D008564:Membrane Potentials; D008959:Models, Neurological; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism
D012964:Sodium; D002794:Choline; D011188:Potassium; D002118:Calcium