Observations on calcium-induced stability of salivary proteins in a lipid-extraction system.
The system described for investigating the effects of small ions on macromolecules of saliva may be applied to other solutions and is amenable to manipulation in order to obtain more specific information. Studies using aqueous solutions of saliva fractions previously separated by gel filtration are being conducted with C/M solutions containing various bivalent cation chloride salts. Preliminary results from these current studies have demonstrated that when the proteins are stabilized they vary as a function of the cation used.
D000328:Adult; D002118:Calcium / Q000378:metabolism*; D002122:Calcium Chloride / Q000494:pharmacology; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D008055:Lipids / Q000032:analysis / Q000494:pharmacology*; D000432:Methanol / Q000494:pharmacology; D011485:Protein Binding / Q000187:drug effects; D011506:Proteins / Q000032:analysis / Q000378:metabolism*; D012463:Saliva / Q000032:analysis / Q000378:metabolism*
D008055:Lipids; D011506:Proteins; D002122:Calcium Chloride; D002118:Calcium; D000432:Methanol