title: Genome of hepatitis B virus: restriction enzyme cleavage and structure of DNA extracted from Dane particles.
abstract: DNA extracted from Dane particles has been characterized by gel electrophoresis and restriction enzyme cleavage with endonuclease R-HaeIII (from Hemophilus aegyptius). Dane particle DNA is proposed to be a double-stranded circular DNA approximately 3600 nucleotides in length containing a single-stranded gap of 600-2100 nucleotides. The endogenous DNA polymerase (DNA nucleotidyl-transferase; deoxynucleosidetriphosphate:DNA deoxynucleotidyltransferase; EC 2.7.7.7) reaction appears to repair this single-stranded gap.
mesh_terms: D004254:DNA Nucleotidyltransferases / Q000378:metabolism; D004261:DNA Replication; D004270:DNA, Circular / Q000032:analysis*; D004279:DNA, Viral / Q000032:analysis* / Q000096:biosynthesis; D003854:Deoxyribonucleotides / Q000032:analysis; D006515:Hepatitis B virus / Q000032:analysis* / Q000201:enzymology; D006801:Humans; D009690:Nucleic Acid Conformation
chemical_list: D004270:DNA, Circular; D004279:DNA, Viral; D003854:Deoxyribonucleotides; D004254:DNA Nucleotidyltransferases