title: Another form of the hereditary persistence of fetal hemoglobin (the Atlanta type)?
abstract: The propositus in a Black family has elevated Hb-F and approximately equal amounts of Hb-A and Hb-S. Hematological and chemical studies of the propositus and his family show elevated Hb-F in the father and a sibling and sickle cell trait in the mother and another sibling. This family is believed to have a form of the hereditary persistence of fetal hemoglobin in which beta chains are produced in cis to the determinant.
mesh_terms: D000755:Anemia, Sickle Cell / Q000235:genetics; D002648:Child; D004592:Electrophoresis, Starch Gel; D005319:Fetal Hemoglobin; D005845:Georgia; D005914:Globins / Q000096:biosynthesis; D006441:Hemoglobin A / Q000032:analysis; D006451:Hemoglobin, Sickle / Q000032:analysis; D006801:Humans; D008297:Male; D010375:Pedigree
chemical_list: D006451:Hemoglobin, Sickle; D005914:Globins; D006441:Hemoglobin A; D005319:Fetal Hemoglobin