title: Investigation of phase transitions of lipids and lipid mixtures by sensitivity differential scanning calorimetry.
abstract: High sensitivity differential scanning calorimetry is applied to the study of the thermotropic behavior of mixtures of synthetic phospholipids in multilamellar aqueous suspensions. The systems dimyristoylphosphatidylcholine dipalmitoylphosphatidylcholine, and  dimyristoylphosphatidylethanolamine-distearoylphosphatidylcholine, although definitely nonideal, exhibit essentially complete miscibility in both gel and liquid crystalline states, while the system dilauroylphosphatidylcholine-distearoylphosphatidylcholine is monotectic with lateral phase separation in the gel state. Comparison of the observed transition curves with theoretical curves calculated from the calorimetrically determined phase diagrams supports a literal interpretation of the phase diagrams.
mesh_terms: D002151:Calorimetry; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D013816:Thermodynamics
chemical_list: D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines