title: Cerebral blood flow and metabolism.
abstract: To date, regional measurements of cerebral blood flow in humans have not been especially helpful in predicting the outcome of acute brain injury. The recent appearance within the medical environment of biologically significant pharmaceuticals labelled with the positron-emitting isotopes 15O, 13N and 11C has made possible the quantitative regional measurement of cerebral metabolism in humans. This advance, coupled with the development of radically new detection systems, will allow the safe measurement of truly regional blood flow and metabolism in humans in the near future. Such information is basic to an understanding of the pathophysiology of acute injury to the brain and the rational prediction of outcome in the individual case.
mesh_terms: D001921:Brain / Q000378:metabolism*; D001930:Brain Injuries / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology*; D002249:Carbon Monoxide Poisoning / Q000378:metabolism / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology*; D006801:Humans; D002534:Hypoxia, Brain / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology*; D010101:Oxygen Consumption; D011379:Prognosis; D011868:Radioisotopes
chemical_list: D011868:Radioisotopes