Combined effect of glucagon and cholecystokinin on gastric secretion in man.
The inhibition of the pentagastrin-stimulated (1 ug/kg b.w./hour) gastric secretion by glucagon (20 ug/kg b.w./hour), cholecystokinin (0.5 IDU/kg b.w./hour), and a combination of these were investigated in 7 volunteers. Glucagon as well as CCK given isolated inhibited the gastric secretion, but no augmentation of inhibition was demonstrated when the hormones were in combination.
D000328:Adult; D002766:Cholecystokinin / Q000494:pharmacology*; D005750:Gastric Juice / Q000378:metabolism*; D005934:Glucagon / Q000494:pharmacology*; D006801:Humans; D008297:Male; D010418:Pentagastrin / Q000494:pharmacology; D012636:Secretory Rate / Q000187:drug effects
D005934:Glucagon; D002766:Cholecystokinin; D010418:Pentagastrin