title: Effect of chlorhexidine on dental plaque formation under periodontal pack.
abstract: In a first experiment, no appreciable differences in plaque formation under periodontal packs were observed in subjects rinsing with and without 0.2% chlorhexidine digluconate. In a second experiment, one gram periodontal packs were coated with 15 to 20 mg of chlorhexidine dihydrochloride powder prior to application and allowed to remain in situ for 4 days. Significantly less plaque formed under periodontal packs with chlorhexidine powder than with control packs. Chlorhexidine dihydrochloride powder may be recommended under periodontal packs for reduction of microbial plaque.
mesh_terms: D001645:Biguanides / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use*; D003773:Dental Plaque / Q000517:prevention & control*; D005069:Evaluation Studies as Topic; D005942:Gluconates / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007180:Incisor; D010511:Periodontal Dressings; D011208:Powders; D012996:Solutions
chemical_list: D001645:Biguanides; D005942:Gluconates; D011208:Powders; D012996:Solutions; C010882:chlorhexidine gluconate; D002710:Chlorhexidine