[An experimental model of electrically-induced coronary thrombosis in the closed chest].
The authors report on an experimental model of coronary thrombosis, electrically induced in the closed thorax. By this technique they succeeded inducing coronary thrombosis with myocardial infarction in 13 cases out of 21. In three cases just disseminated myocardial necrosis was proved. All of the other animals showed vast myocardial infarctions. Coronarography, arterial pressures, typical shifts of serum enzymes, decrease of thrombocytes and fibrinogen and elevation of spontaneous fibrinolysis during the first hours proved to be valuable for the confirmation of successful inducing of thrombosis; in individual cases, however, these estimations yield no absolute certainty.
D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001784:Blood Gas Analysis; D001794:Blood Pressure; D003327:Coronary Disease / Q000209:etiology / Q000473:pathology*; D003331:Coronary Vessels / Q000473:pathology; D003402:Creatine Kinase / Q000097:blood; D004195:Disease Models, Animal; D004285:Dogs; D004556:Electric Injuries / Q000473:pathology; D005340:Fibrinogen; D005342:Fibrinolysis; D009203:Myocardial Infarction / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D010976:Platelet Count; D013997:Time Factors
D005340:Fibrinogen; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase
Experimentelles Modell einer elektrisch induzierten Koronarthrombose am geschlossenen Thorax.