[Effect of insulin on the development of the tooth germ in mice].
After recalling the interactions affecting dental differentiation, the authors analyze the effects of various concentrations in insulin on dental rudiments cultivated in vitro. They found: an oedema causing histological lesions, no anticipation of cell differentiation or stimulation of collagen secretion, a decrease in mitotic activity but stimulation of thymidine 3H incorporation after short contact times.
D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D004247:DNA / Q000096:biosynthesis; D066298:In Vitro Techniques; D007328:Insulin / Q000494:pharmacology*; D051379:Mice; D008938:Mitosis / Q000187:drug effects; D008963:Molar / Q000166:cytology / Q000196:embryology / Q000378:metabolism; D014083:Tooth Germ / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism
D007328:Insulin; D004247:DNA
Action de l'insulin sur le développement de l'ébauche dentaire chez la souris