Suppression of lactation by an antiestrogen, tamoxifen.
The efficacy of a new antiestrogen, tamoxifen, in the suppression of lactation was tested in a placebo-controlled double-blind trial in 150 puerperal women. It proved to be very effective in preventing milk secretion and breast engorgement when its administration was commenced within two hours after delivery. No side effects were observed. Two dosage schedules were compared.
D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007774:Lactation / Q000187:drug effects*; D049590:Postpartum Period; D011247:Pregnancy; D013629:Tamoxifen / Q000008:administration & dosage / Q000494:pharmacology*
D013629:Tamoxifen