title: The heterogeneity of leukemic reticuloendotheliosis, "hairy cell leukemia". Evidence for its monocytic origin.
abstract: The presence of B, T, and monocyte markers were studied on the spleen and peripheral blood mononuclear cells from two patients with leukemic reticuloendotheliosis. A high proportion of cells from both patients bore a receptor for cytophilic antibody, both in suspension and frozen tissue section. Cells in suspension lacked surface immunoglobulins or a receptor for sheep red blood cells. These results favor the evidence that "hairy cells" are monocytic in origin.
mesh_terms: D000818:Animals; D000918:Antibody Specificity; D001666:Binding Sites, Antibody; D003165:Complement System Proteins / Q000032:analysis; D005260:Female; D006801:Humans; D007938:Leukemia / Q000473:pathology*; D007951:Leukemia, Myeloid / Q000209:etiology / Q000473:pathology; D008206:Lymphatic Diseases / Q000473:pathology*; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000276:immunology; D012157:Mononuclear Phagocyte System / Q000473:pathology; D013154:Spleen / Q000473:pathology
chemical_list: D003165:Complement System Proteins