title: [Studies on the pharmacodynamics and compatibility of the local anesthetic carticain].
abstract: Two local anesthetics were compared with a placebo with regard to subjective tolerance and influence on driving capacity in a double blind test in eight male probands. Neither performance, the ability to respond, reactivity, nor fine motor coordination were reduced or impaired five to sixty minutes after a submucous injection of 3.6 ml of the local anesthetics tested. There were no changes of self-evaluation in the sense of a changed active-passive polarity.
mesh_terms: D000766:Anesthesia, Dental; D000779:Anesthetics, Local / Q000009:adverse effects / Q000627:therapeutic use*; D001334:Automobile Driving; D004341:Drug Evaluation; D004361:Drug Tolerance; D008012:Lidocaine / Q000627:therapeutic use*; D011437:Propylamines / Q000009:adverse effects; D012649:Self Concept; D013876:Thiophenes / Q000627:therapeutic use*
chemical_list: D000779:Anesthetics, Local; D011437:Propylamines; D013876:Thiophenes; D008012:Lidocaine
vernacular_title: Untersuchungen zur Pharmakodynamik und Verträglickeit des Lokalanästhetikums Carticain