Isochromosome 17 in a case of chronic erythroleukaemia.
In a patient with chronic erythroleukaemia in isochromosome 17q was identified in all bone marrow metaphases analyzed. In addition, these cells were characterized by hypodiploidy and the presence of 3 different marker chromosomes. Approximately 50% of dividing cells in the marrow were bizarre-looking polyploids. The identification by Giemsa banding of i(17q) in this case of erythroleukaemia supports the concept that there are common cytogenetic characteristics among malignant myeloproliferative disorders.
D001853:Bone Marrow / Q000648:ultrastructure; D001854:Bone Marrow Cells; D002869:Chromosome Aberrations; D002902:Chromosomes, Human, 16-18; D002908:Chronic Disease; D005260:Female; D006801:Humans; D004915:Leukemia, Erythroblastic, Acute / Q000235:genetics*; D008875:Middle Aged; D011123:Polyploidy