title: Oral health of patients with cystic fibrosis and their siblings.
abstract: Caries prevalence, oral hygiene index, submandibular gland hypertrophy, occlusion, dental hypoplasia, and staining of permanent teeth were evaluated in 63 patients with cystic fibrosis (CF) who were maintained on a regimen of broad-spectrum antibiotics and oral pancreatin, and the findings were compared with those of their near-aged siblings. Gland hypertrophy and dental staining were increased in patients with CF whereas caries was significantly decreased. No other significant differences were found.
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000188:drug therapy*; D003731:Dental Caries / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D009909:Oral Health; D009910:Oral Hygiene; D010194:Pancreatin / Q000627:therapeutic use*; D013752:Tetracycline / Q000009:adverse effects; D014075:Tooth Discoloration / Q000209:etiology
chemical_list: D000900:Anti-Bacterial Agents; D010194:Pancreatin; D013752:Tetracycline