title: Continuous negative chest-wall pressure. Successful use for severe respiratory distress in an adult.
abstract: Continuous negative pressure (CNP) around the chest-wall and lower parts of the body was used to treat progressively alveolar disease. Therapy with CNP produced a substantial increase in arterial oxygen tension that was sustained and permitted a decrease in oxygen requirements to 40% within 24 hours. There were concomitant decreases in intrapulmonary right-to-left shunt and respiratory frequency. During CNP therapy, no adverse effects on heart rate or blood pressure were detected.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000209:etiology / Q000628:therapy*; D008171:Lung Diseases / Q000150:complications; D008722:Methods; D011650:Pulmonary Alveoli; D012122:Ventilators, Mechanical / Q000295:instrumentation*