title: [Development of terminal leukemia in a patient with Hodgkin's disease].
abstract: A morphological, cytochemical, genetic and autoradiographic examination of the myeloblasts observed in the terminal phase of a patient with Hodgkin's disease is reported. Comparison is made with the literature data in an assessment of the possible aetiopathogenesis of this association, which has become increasingly frequent in recent years in coincidence with the more widespread employment of more radical radio- and polychemotherapeutical management.
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects; D001345:Autoradiography; D002869:Chromosome Aberrations; D006689:Hodgkin Disease / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D007953:Leukemia, Radiation-Induced; D008297:Male; D011878:Radiotherapy / Q000009:adverse effects; D013997:Time Factors; D014529:Uridine / Q000378:metabolism; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D014750:Vincristine; D014529:Uridine
vernacular_title: Evoluzione terminale leucemica in un paziente con morbo di Hodgkin