A study of antibiotic usage in compound mandibular fractures.
The need for antibiotic coverage in compound mandibular fractures was tested in 64 patients with fractures in tooth-bearing areas in a study that began in January 1971 and ended in May 1974. Half of the patients received antibiotic coverage as part of the management of their fractures; the other half did not receive antibiotics. Problems related to infection at a fracture site developed in only 6.25% of patients treated with antibiotics. Infections directly associated with fractures developed in 50.33% of patients who did not receive antibiotic coverage.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000150:complications / Q000517:prevention & control*; D002506:Cephalexin / Q000627:therapeutic use; D002981:Clindamycin / Q000627:therapeutic use; D004917:Erythromycin / Q000627:therapeutic use; D005260:Female; D005592:Fracture Fixation; D005593:Fracture Fixation, Internal; D005599:Fractures, Ununited / Q000209:etiology; D006801:Humans; D008034:Lincomycin / Q000627:therapeutic use; D008297:Male; D008336:Mandibular Diseases / Q000150:complications / Q000517:prevention & control*; D008337:Mandibular Fractures / Q000150:complications / Q000601:surgery*; D010019:Osteomyelitis / Q000209:etiology; D010406:Penicillins / Q000627:therapeutic use; D011183:Postoperative Complications; D013165:Splints; D014081:Tooth Extraction
D000900:Anti-Bacterial Agents; D010406:Penicillins; D002981:Clindamycin; D004917:Erythromycin; D008034:Lincomycin; D002506:Cephalexin