[Discovery of age effect in molecular structure of collagen].
The temperature dependences of the NMR-broad line spectra of collagen from Achilles tendon have been investigated. It is found that the narrow doublet splitting collapsed at certain temperature Tx determined by age of collagen sample. The Tx varied from approx. +35 degrees C for 8 years sample to -2 degrees C for 82 years. The interpretation of results obtained is based on the theory of NMR spectra of diffusing water molecules.
D000125:Achilles Tendon / Q000254:growth & development* / Q000378:metabolism; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D003094:Collagen / Q000378:metabolism; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008875:Middle Aged; D013696:Temperature
D003094:Collagen
Obnaruzhenie vozrastnykh izmeneniĭ v molekuliarnoĭ strukture kollagena.