Effects of dietary sucrose levels on extracellular polysaccharide metabolism of human dental plaque.
The effects of increased and low dietary sucrose levels on the biochemical activities and composition of 4- and 12-day plaque were investigated in eight young men. The subjects were fed supervised, nutritionally adequate diets. Dextran hydrolase, levan hydrolase, and total carbohydrate content were increased during a sucrose-rich diet while invertase activity was decreased. Base-extractable carbohydrate was decreased in four-day plaque during the sucrose-rich diet. Glucosyltransferase and fructosyltransferase activity, buffer-soluble carbohydrate, and buffer-soluble protein were also determined.
D000328:Adult; D050260:Carbohydrate Metabolism; D003773:Dental Plaque / Q000201:enzymology / Q000378:metabolism* / Q000382:microbiology; D003911:Dextrans; D004040:Dietary Carbohydrates / Q000378:metabolism; D005632:Fructose; D005964:Glucosyltransferases / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000378:metabolism; D006602:Hexosyltransferases / Q000378:metabolism; D006801:Humans; D008297:Male; D011135:Polysaccharides, Bacterial / Q000378:metabolism*; D013393:Sucrase / Q000378:metabolism; D013395:Sucrose / Q000494:pharmacology*
D003911:Dextrans; D004040:Dietary Carbohydrates; D011135:Polysaccharides, Bacterial; D005632:Fructose; D013395:Sucrose; D005964:Glucosyltransferases; D006602:Hexosyltransferases; D006026:Glycoside Hydrolases; D013393:Sucrase; C021512:levanase