title: Long-term follow-up results of bilateral thalamotomy for parkinsonism.
abstract: 27 patients who underwent bilateral thalamotomy for parkinsonism over the past 10 years have been clinically evaluated. Mean follow-up period was 6.2 years after second surgery. In these cases, 8 returned to full social life without any medication, 4 were capable of social life with medical treatment, 6 were self-sufficient and 3 were semi-self-sufficient in ADL, respectively. Therapeutic drug doses were reduced in all cases. L-Dopa-induced dyskinesia was not observed after second surgery. Speech disturbance, which was not severe, was recognized in 12 cases as a complication.
mesh_terms: D000328:Adult; D005500:Follow-Up Studies; D007839:Functional Laterality; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008569:Memory Disorders / Q000209:etiology; D008875:Middle Aged; D010276:Parasympatholytics / Q000627:therapeutic use; D010300:Parkinson Disease / Q000188:drug therapy / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology; D013064:Speech Disorders / Q000209:etiology; D013788:Thalamus / Q000601:surgery*
chemical_list: D010276:Parasympatholytics; D007980:Levodopa