title: The Edinburgh spleen: source of a validated Kveim-Siltzbach test material.
abstract: Although it is true that some Kveim-Siltzbach test suspension may for reasons unknown behave in a totally nonspecific way and so be useless in the confirmation of active sarcoidosis, the experience with the Edinburgh spleen has shown that it is also true that a preparation can be made which acts specifically in the sarcoid context and fulfils all the Siltzbach criteria. The active principle probably resides in the membrane components of sarcoid tissue cells.
mesh_terms: D000941:Antigens; D006801:Humans; D007731:Kveim Test; D008861:Microsomes; D012507:Sarcoidosis / Q000175:diagnosis / Q000473:pathology; D012606:Scotland; D012882:Skin Tests; D013154:Spleen
chemical_list: D000941:Antigens