Familial leukaemia. A report of three cases of acute leukaemia in a Brazilian family.
The authors reported of three individuals observations -- three siblings in a family -- of acute lymphoid leukaemia. Cytogenetic studies carried out in peripheral blood, lymphocyte cultures with PHA, in two patients and in several relatives, showed numerical and structural alterations. The third patient died before the cytogenetic studies were done.
D000293:Adolescent; D001938:Brazil; D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D010375:Pedigree