[Spontaneous radial segmentation of the nuclei of myeloblasts in a case of chronic granulocytic leukemia during blastic crisis. an electromicroscopical study (author's transl)].
By means of electron microscopy, myeloblasts with spontaneous radial segmentation of the nuclei from a patient with micromegakaryotic chronic myelosis in the blastic crisis were analysed. The centriol was found in the center of the cells and microtubules were found between the segments of the nucleus. These observations support the hypothesis that spontaneous radial segmentations of the nuclei of tumor cells is associated with a contractile process of the microtubules with split the nucleus.
D000328:Adult; D001853:Bone Marrow / Q000648:ultrastructure*; D001854:Bone Marrow Cells; D002467:Cell Nucleus; D006801:Humans; D007951:Leukemia, Myeloid / Q000097:blood*; D008297:Male; D008854:Microscopy, Electron; D008870:Microtubules
Spontane radialsegmentation de myeloblastenkerne einer chronis"h-myeloischen leukämie im blastenschub eine elektronenmikroskopische studie