[Action of the sera from acute leukemia patients on lymphocytic transformation].
The authors examined in vitro the action of sera, obtained from patients with acute leucosis during the first attack and relapse on PHA (phytoheagglutinins)-M-reactivity of lymphocytes, obtained from healthy donors and olymphocytes obtained from leucemic patients. They found that sera inhibited in vitro the effects of PHA-M both on lymphocytes of patients and of healthy donors. There was stimulating effect of sera in vitro in single cases under autologic conditions.
D000818:Animals; D002417:Cattle; D002478:Cells, Cultured; D006801:Humans; D007106:Immune Sera / Q000494:pharmacology*; D037102:Lectins / Q000494:pharmacology; D015470:Leukemia, Myeloid, Acute / Q000276:immunology*; D008213:Lymphocyte Activation / Q000187:drug effects*; D008214:Lymphocytes / Q000276:immunology; D012008:Recurrence
D007106:Immune Sera; D037102:Lectins
Deĭstvie na serumi ot bolni s ostra levkoza vurkhu limfotsitnata transformatsiia