title: Gastroesophageal involvement in herpes simplex.
abstract: Herpes simplex in the gastric mucosa has not been previously described. The case presented here describes gastritis and esophagitis resulting from herpes simplex in a patient being treated with immunosuppressive agents. These changes were confirmed endoscopically and radiographically. Biopsy specimens of the gastric and esophageal mucosa showed eosinophilic intranuclear inclusion bodies typical of herpes simplex. The pathogenesis and pathological appearance of herpetic gastritis and esophagitis are presented.
mesh_terms: D000328:Adult; D004848:Epithelium / Q000648:ultrastructure; D004935:Esophageal Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D004941:Esophagitis / Q000209:etiology*; D005260:Female; D005753:Gastric Mucosa / Q000648:ultrastructure; D005756:Gastritis / Q000000981:diagnostic imaging / Q000209:etiology*; D006561:Herpes Simplex / Q000150:complications*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007181:Inclusion Bodies, Viral; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy; D010437:Peptic Ulcer / Q000000981:diagnostic imaging / Q000209:etiology; D011859:Radiography; D013276:Stomach Ulcer / Q000000981:diagnostic imaging / Q000209:etiology
chemical_list: D007166:Immunosuppressive Agents