title: Drug evaluation of pyrantel pamoate against Ancylostoma, Toxocara, and Toxascaris in eleven dogs.
abstract: Eleven dogs dosed at approximately the recommended rate of 1.029 mg of pyrantel pamoate/kg of body weight were used. The efficacy against Ancylostoma in the 11 dogs was 99% (av; min-max, 94-99%). In 4 dogs with both Toxocara and Ancylostoma, average efficacy against Toxocara was 96%, and in 5 dogs with both Toxoscaris and Ancylostoma, efficacy against Toxascaris was 93%. Only 2 dogs of the 11 were infected with the 3 species; the average efficacy was 90%. There appeared to be no activity against the Trichuris found in one dog and the Dipylidium found in another. Treated dogs did not vomit or have other noticeable ill effects.
mesh_terms: D000724:Ancylostomiasis / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D001196:Ascariasis / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary*; D011715:Pyrantel / Q000031:analogs & derivatives*; D011716:Pyrantel Pamoate / Q000627:therapeutic use*; D014120:Toxocariasis / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D011715:Pyrantel; D011716:Pyrantel Pamoate