Electrolyte concentration in the hypertrophic salivary glands of incisor-amputated rats.
The effect of periodic amputations of the lower incisors of the rat on the electrolyte concentration in the major salivary glands was studied. The incisor amputations caused a hypertrophy of the parotid, submandibular and sublingual glands. The resulting increased weight of the salivary glands was due to a higher dry mass. In general, the electrolyte concentration showed higher values in the salivary gland tissues of the incisor-amputated animals. Considering the parotid, submandibular and sublingual glands respectively, the Na+ concentration was increased by 47%, 50% and 14%; and Mg2+ concentration by 377%, 126+ and 376%. Inorganic phosphorus increased 45% in the parotid, 25% in the subnamdibular and was unchanged in the sublingual gland. K+ concentration increased in the submandibular (12%) and sublingual (100%) glands but decreased in the parotid (24%). The Na+/k+ ratio was higher in the parotid (82%) and submandibular (37%) glands and lower in the sublingual gland (84%). The electrolyte concen-ration changes are discussed in relation to the mechanism and type of stimulation promoted by the incisor-amputations on the major salivary glands of the rat.
D000671:Amputation, Surgical; D000818:Animals; D004573:Electrolytes / Q000378:metabolism*; D005260:Female; D006984:Hypertrophy / Q000378:metabolism; D007180:Incisor / Q000601:surgery*; D008274:Magnesium / Q000378:metabolism; D010758:Phosphorus / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D051381:Rats; D012466:Salivary Gland Diseases / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism; D014867:Water / Q000378:metabolism
D004573:Electrolytes; D014867:Water; D010758:Phosphorus; D012964:Sodium; D008274:Magnesium; D011188:Potassium