title: Effects of anti-inflammatory steroids on mouse embryonic movements during palatal development.
abstract: The frequency of spontaneous embryonic muscular movements was recorded for embryos from mice treated with cortisone or triamcinolone. Movement was significantly reduced in A/J strain mouse embryos exposed to these anti-inflammatory agents. Cleft palates induced by the drugs may originate from failure of the embryonic tongue to be withdrawn from between the palatine shelves.
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D003348:Cortisone / Q000494:pharmacology*; D004622:Embryo, Mammalian / Q000502:physiology*; D051379:Mice; D008810:Mice, Inbred C57BL / Q000196:embryology; D008815:Mice, Inbred Strains / Q000196:embryology; D009068:Movement; D010159:Palate / Q000196:embryology*; D014221:Triamcinolone / Q000494:pharmacology*
chemical_list: D000893:Anti-Inflammatory Agents; D014221:Triamcinolone; D003348:Cortisone