The treatment of acute childhood leukemia: predictions for the future based on extrapolations from  the past.
Further progress in the treatment of acute leukemia involves a careful assessment of host and disease factors in each child and the selection of a therapeutic regimen which interacts with these factors to provide the maximum chance for survival. For some children, this therapy can be carried out in the community by expertly trained hematologist-oncologists; for others, the best treatment will involve clinical research at a center. Such a general approach has the best chance of fulfilling the optimistic survival projections made by the President's Cancer Panel in 1973 for acute lymphocytic leukemia.
D001932:Brain Neoplasms / Q000517:prevention & control; D004359:Drug Therapy, Combination; D006801:Humans; D007938:Leukemia / Q000276:immunology; D007945:Leukemia, Lymphoid / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy; D007958:Leukocyte Count; D008727:Methotrexate / Q000627:therapeutic use; D011379:Prognosis; D012075:Remission, Spontaneous
D008727:Methotrexate