Histochemical demonstration of acid hydrolase activity in internal dentinal resorption.
The enzymes acid phosphatase (E.C. 3.133) and beta-glucuronidase (E.C. 3.2.1.31) have been demonstrated in dentin-resorbing cells by means of histochemistry. Addition of specific enzyme inhibitros revealed that the acid phosphatase of these cells was sensitive to fluride, copper, and m?OLYBDATE BUT RESISTANT TO Tartrate. The same pattern of enzyme activity has previously been found in bone-resorbing cells.
D000135:Acid Phosphatase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D003804:Dentin / Q000201:enzymology* / Q000473:pathology; D005966:Glucuronidase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006801:Humans; D012391:Root Resorption / Q000201:enzymology* / Q000473:pathology
D000135:Acid Phosphatase; D005966:Glucuronidase