title: Affective changes in chronic opiate use.
mesh_terms: D000328:Adult; D000374:Aggression / Q000187:drug effects; D001007:Anxiety / Q000139:chemically induced; D003863:Depression / Q000139:chemically induced; D004644:Emotions / Q000187:drug effects*; D005059:Euphoria; D006556:Heroin Dependence / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012934:Social Isolation; D013997:Time Factors