Analysis of the dextranase activity produced by an oral strain of Bacteroides ochraceus.
An anaerobic, gram-negative, dextranase-producing filamentous bacterium isolated from human dental plaque has been identified as a strain of Bacteroides ochraceus. The inducible intracellular dextran-degrading activities produced by this microoranism can be fractionated into endohydrolytic and exohydrolytic enzymes with distinct pH optima. These enzymes reduce the apparent rate of glucan production from sucrose by the dextransucrase produced by Streptococcus mutans and consequently may influence the in vivo production of polysaccharides involved in plaque accumulation and metabolism.
D001439:Bacteroides / Q000201:enzymology*; D003773:Dental Plaque / Q000382:microbiology*; D003910:Dextranase / Q000037:antagonists & inhibitors / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology; D005964:Glucosyltransferases / Q000378:metabolism; D011135:Polysaccharides, Bacterial / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D013295:Streptococcus mutans / Q000201:enzymology
D011135:Polysaccharides, Bacterial; D005964:Glucosyltransferases; D003910:Dextranase