Comparison of a slow release formulation of oxprenolol with conventional oxprenolol in the treatment of hypertension.
Patients with moderate to severe hypertension were studied during a 12-week period, during which they were given a slow release formulation of oxprenolol once daily, in a dosage equal to their previous total daily dose of oxprenolol given in divided doses. There were no systematic differences between blood pressures at the beginning and end of the 12-week period. The once-daily dosage was well tolerated and was preferred by the patients. This regime offers advantages in terms of patient compliance with lifelong therapy in what is usually a symptomless condition.
D000328:Adult; D000368:Aged; D003692:Delayed-Action Preparations; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010096:Oxprenolol / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use
D003692:Delayed-Action Preparations; D010096:Oxprenolol