Autosomal dominant hypodontia with nail dysgenesis. Report of twenty-nine cases in six families.
Clinical details of twenty-three of twenty-nine cases of hypodontia and nail dysgenesis are presented. The classic features of severe hypodontia and a distinctive congenital nail defect were found in all families. The use of a simple method of sweat testing disclosed a minor deficiency of sweating in one family.
D000015:Abnormalities, Multiple / Q000150:complications / Q000235:genetics* / Q000503:physiopathology; D000293:Adolescent; D000328:Adult; D000848:Anodontia / Q000150:complications / Q000235:genetics* / Q000503:physiopathology; D002648:Child; D002875:Chromosomes; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D009264:Nails, Malformed / Q000150:complications / Q000235:genetics* / Q000503:physiopathology; D010375:Pedigree; D013545:Sweat Glands / Q000503:physiopathology