Diarrhoea and colitis associated with antibiotic treatment.
Sixteen cases of colitis developing within twenty-one days of antibiotic therapy are reported. There was a wide range of disease severity. Lincomycin and Clindamycin were implicated in twelve. The colitis was of two pathological patterns pseudomembranous colitis and "non-specific" colitis. There is a relative sparing of the rectum in some cases making the diagnosis more difficult on sigmoidoscopy.
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002981:Clindamycin / Q000009:adverse effects; D003092:Colitis / Q000139:chemically induced* / Q000473:pathology / Q000628:therapy; D003106:Colon / Q000473:pathology; D003967:Diarrhea / Q000139:chemically induced* / Q000628:therapy; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced / Q000473:pathology; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008034:Lincomycin / Q000009:adverse effects; D008297:Male; D008875:Middle Aged
D000900:Anti-Bacterial Agents; D002981:Clindamycin; D008034:Lincomycin