Microbial iron chelates with iron donor properties in hemoglobin-synthesizing cells.
Iron incorporation into Friend virus infected leukemic murine spleen cells was studied using the two fungal iron trihydroxamates, fusigen and ferricrocin. Incorporation of 55Fe was measured by isolation of hemoglobin after dimethylsulfoxide-induced hemoglobin synthesis and compared with iron incorporation from 55Fe-labeled ferric citrate.
D000818:Animals; D002999:Clone Cells; D005622:Friend murine leukemia virus; D006454:Hemoglobins / Q000096:biosynthesis*; D007501:Iron / Q000378:metabolism*; D007502:Iron Chelating Agents / Q000378:metabolism*; D004915:Leukemia, Erythroblastic, Acute / Q000097:blood / Q000378:metabolism*; D051379:Mice; D013154:Spleen / Q000378:metabolism*
D006454:Hemoglobins; D007502:Iron Chelating Agents; D007501:Iron