title: [A study on the cytotoxic action of gold-copper alloy by means of tissue culture (author's transl)].
abstract: Nine kinds of gold-copper alloy containing copper of various contents, such as 91% Au-9% Cu, 83% Au-17% Cu, 75% Au-25% Cu, 58% Au-42% Cu, 50% Au-50% Cu, 25% Au-75% Cu, 20% Au-80% Cu, 15% Au-85% Cu, 10% Au-90% Cu and two pure metals of copper and gold, were used to analyse cytotoxic action of gold-copper alloy. A cytotoxicity of these alloys and metals was observed by replicate culture using L-strain cells. The results obtained, were as follows; When the range of copper content was from 0 to 42%, the alloys showed no cytotoxic reaction. There was, however, strong cytotoxic action in the gold-copper alloys containing copper of 50% or more.
mesh_terms: D002455:Cell Division / Q000187:drug effects; D003300:Copper / Q000633:toxicity*; D003722:Dental Alloys / Q000633:toxicity*; D006047:Gold Alloys / Q000633:toxicity*; D006128:Growth; D007739:L Cells / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure
chemical_list: D003722:Dental Alloys; D006047:Gold Alloys; D003300:Copper