title: Treatment of chronic muco-cutaneous candidiasis by lymphocyte transfer factor.
abstract: A beneficial clinical effect from the administration of lymphocyte transfer factor is described in six patients with idiopathic early onset chronic muco-cutaneous candidiasis. Five patients in two families showed a familial disease pattern. Dermal anergy and failure to produce migratory inhibition factor with intact general immune function were found in patients tested. Antifungal chemotherapy was effective in clearing or markedly reducing the candidiasis and remission was maintained by repeated injections of transfer factor. Therapy was monitored using Candida skin test.
mesh_terms: D000293:Adolescent; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D002179:Candidiasis, Cutaneous / Q000188:drug therapy / Q000235:genetics / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D014165:Transfer Factor / Q000627:therapeutic use*
chemical_list: D014165:Transfer Factor; D000666:Amphotericin B; D005437:Flucytosine