Myopathies related to diabetes mellitus and other metabolic diseases.
Although it has long been known that both large and small blood vessels are abnormal in the tissues of diabetic patients, recent work has emphasized the widening of capillary basement membranes in diabetic tissues. Current views of  the nature of this lesion and its relationship to diabetes are discussed and diabetic muscle and nerve lesions are emphasized. Other metabolic diseases with significant muscle pathology are types II, III and VII glycogen storage diseases. Myopathy with abnormal mitochondria is reviewed.
D001485:Basement Membrane / Q000473:pathology; D048909:Diabetes Complications; D003925:Diabetic Angiopathies / Q000209:etiology / Q000473:pathology; D003929:Diabetic Neuropathies / Q000175:diagnosis; D003937:Diagnosis, Differential; D006009:Glycogen Storage Disease Type II / Q000473:pathology; D006010:Glycogen Storage Disease Type III / Q000473:pathology; D006014:Glycogen Storage Disease Type VII / Q000473:pathology; D006801:Humans; D008659:Metabolic Diseases / Q000150:complications*; D009135:Muscular Diseases / Q000175:diagnosis / Q000209:etiology*; D009469:Neuromuscular Junction / Q000473:pathology; D010525:Peripheral Nerves / Q000473:pathology