Report of a kindred with bone lesions and subcutaneous abscesses of unknown etiology.
This case report concerns a 12-year-old boy who had a 9-year history of mandibular lesions of unknown origin. The mandible showed changes resembling chronic osteomyelitis. The tibia and temporal bone also exhibited radiolucencies. Many subcutaneous abscesses were present. The boy died at the age of 14 years as a result of rupture of the aorta. In his family, there were seven members who had bone lesions and eleven who suffered from skin abscesses.
D000038:Abscess / Q000235:genetics* / Q000473:pathology; D002648:Child; D002908:Chronic Disease; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000235:genetics* / Q000473:pathology; D010019:Osteomyelitis / Q000235:genetics* / Q000473:pathology; D010375:Pedigree; D012871:Skin Diseases / Q000235:genetics* / Q000473:pathology