Severe haemolytic anaemia complicating infectious mononucleosis.
The case record of a patient suffering from infectious mononucleosis, complicated by severe haemolytic anaemia, with overt intravascular haemolysis, is reported. Investigation of such cases usually shows a high titre of cold agglutinins with anti-i specificity. In the case reported, the results of serological investigations were atypical, and suggested that cold agglutinins with anti-L activity (rather than anti-i) were predominant in the aetiology of the haemolysis.
D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000209:etiology*; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications*; D008297:Male