Porphyria cutanea tarda and the pill: case report.
A patient is described who developed porphyria cutanea tarda in association with the use of a contraceptive pill. The relationship to porphyrin metabolism as at present understood, as well as the significance of abdominal pain and change in psyche, is discussed. Stopping the pill has been associated with a remission.
D000005:Abdomen; D000328:Adult; D003276:Contraceptives, Oral / Q000009:adverse effects*; D003863:Depression / Q000139:chemically induced; D004338:Drug Combinations; D004997:Ethinyl Estradiol / Q000009:adverse effects; D005260:Female; D006801:Humans; D009644:Norgestrel / Q000009:adverse effects; D010146:Pain / Q000139:chemically induced; D011164:Porphyrias / Q000139:chemically induced* / Q000378:metabolism; D011166:Porphyrins / Q000378:metabolism
D003276:Contraceptives, Oral; D004338:Drug Combinations; D011166:Porphyrins; D009644:Norgestrel; D004997:Ethinyl Estradiol