Gastric pathology produced by hypothalamic lesions in rats.
Rats made aphagic and adipsic by damage to the lateral hypothalamus develop gastric lesions and lose body weight excessively over a four day period. Control observations indicate that these effects cannot be accounted for by food and water deprivation or by operative trauma. The possibility that gastric lesions may contribute to aphagia or anorexia is discussed.
D000818:Animals; D001835:Body Weight; D004327:Drinking Behavior / Q000502:physiology; D005247:Feeding Behavior / Q000502:physiology; D001068:Feeding and Eating Disorders / Q000209:etiology; D005508:Food Deprivation; D006801:Humans; D007031:Hypothalamus / Q000473:pathology / Q000502:physiology*; D008297:Male; D008954:Models, Biological; D051381:Rats; D013276:Stomach Ulcer / Q000150:complications / Q000209:etiology* / Q000473:pathology; D013997:Time Factors; D014868:Water Deprivation