title: Blood lymphocytes in acute lymphoid leukaemia in remission and in relapse. Predictive value of electrophoretic mobility and refringence.
abstract: Blood lymphocytes were studied during the evolution of acute lymphocytic leukaemia, including remissions and relapses, under chemotherapy and immunotherapy. Lymphoblasts migrate as a uniform population and have a mean electrophoretic mobility of 1.04 mum-sec-1. V-1cm. These lymphoblasts are also refringent. The relapse seems to be preceded by a slowing of the electrophoretic mobility of fast cells and a rise in the percentage of refringent lymphocytes.
mesh_terms: D000293:Adolescent; D002648:Child; D004586:Electrophoresis; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007945:Leukemia, Lymphoid / Q000097:blood*; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D055095:Optics and Photonics; D012008:Recurrence; D012075:Remission, Spontaneous
chemical_list: D007136:Immunoglobulins