Pseudo-malignant lesions in Paget's disease of bone.
Two patients with unusual features of Paget's disease are reported. In one patient a circumferential focal and periosteally based mass of Paget's disease presented as a mass lesion superimposed on the sclerotic phase of Paget's disease in the distal femur. Biopsy of the mass showed Paget's disease without neoplasia. The mass has remained unchanged roentgenographically in a 2 year period. In a second patient, a lesion occurred in the mid-portion of the tibia and showed features of the early and radiolucent phase of Paget's disease. In a 4 year period, the lesion has progressed to a more sclerotic phase and to occupy the proximal end of the tibia as well as its mid and lower portions.
D000368:Aged; D001706:Biopsy; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005269:Femur / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D010001:Osteitis Deformans / Q000000981:diagnostic imaging* / Q000473:pathology; D012516:Osteosarcoma / Q000000981:diagnostic imaging* / Q000473:pathology; D011859:Radiography; D013628:Talus / Q000000981:diagnostic imaging; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology