Cytochemical studies on golgi apparatus, GERL, and lysosomes in neurons of dorsal root ganglia in mice.
Cytochemically demonstrable thiamine pyrophosphatase activity is present in the innermost Golgi element in both small and large neurons of the dorsal root ganglia in CF1, C57 black, and C57 beige mice, thus resembling the neurons of rat dorsal root ganglia. The localization of acid phosphatase (EC 3.1.3.2) activity in the large neurons of dorsal root ganglia in these mice is also similar to that in rats; it is not demonstrable in Golgi elements but is present in GERL and in three types of lysosomes apparently derived from GERL. However, the small neurons of the mouse differ from those of the rat in showing acid phosphatase activity in all elements of the Golgi apparatus. In the mouse neurons the acid phosphatase activity of residual bodies is "latent," i.e., it is not demonstrable in well-preserved cells.
D000135:Acid Phosphatase / Q000032:analysis; D000818:Animals; D004721:Endoplasmic Reticulum / Q000648:ultrastructure*; D005260:Female; D005725:Ganglia, Autonomic / Q000648:ultrastructure*; D005727:Ganglia, Spinal / Q000648:ultrastructure*; D006056:Golgi Apparatus / Q000201:enzymology / Q000648:ultrastructure*; D006651:Histocytochemistry; D008247:Lysosomes / Q000648:ultrastructure*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009474:Neurons / Q000201:enzymology / Q000648:ultrastructure; D011755:Pyrophosphatases / Q000032:analysis; D013831:Thiamine
D000135:Acid Phosphatase; D011755:Pyrophosphatases; D013831:Thiamine