title: Continuous culture studies on the growth and physiology of Streptococcus mutans.
abstract: We examined the effects of nutritional limitations on the production of lactic acid by Streptococcus mutans grown at low growth rates in continuous culture. Lactic acid production was greater in nitrogen- and phosphate-limited continuous cultures than in glucose-limited conditions. These results are correlated with the release of calcium from enamel in cellfree broths from various fermentations.
mesh_terms: D002478:Cells, Cultured; D003470:Culture Media; D005947:Glucose / Q000378:metabolism; D007773:Lactates / Q000096:biosynthesis*; D009584:Nitrogen / Q000378:metabolism; D010710:Phosphates / Q000378:metabolism; D013291:Streptococcus / Q000502:physiology*; D013295:Streptococcus mutans / Q000254:growth & development / Q000378:metabolism / Q000502:physiology*
chemical_list: D003470:Culture Media; D007773:Lactates; D010710:Phosphates; D005947:Glucose; D009584:Nitrogen