A gradient of adhesive specificity in developing avian retina.
Cell-cell adhesion was examined in the developing chick neural retina. A dorsoventral gradient of adhesive specificity in dissociated cells was detected which exhibits a complementarity such that the highest cell-cell affinities are exhibited between cells derived from the extremes of the gradient. If a nasotemporal gradient exists it must exhibit significantly lower cell-cell affinity. The relevance of these findings to pattern formation in the nervous system is discussed.
D000367:Age Factors; D000818:Animals; D002448:Cell Adhesion; D002642:Chick Embryo; D012160:Retina / Q000033:anatomy & histology / Q000166:cytology / Q000196:embryology*