A case of chronic granulocytic leukemia in a dog.
A case of chronic granulocytic leukemia was diagnosed in a ten year old miniature poodle and was observed for four and one half years. Methods of diagnosis and characteristic features are described. A persistent granulocytosis with a preponderance of mature forms and the absence of a detectable underlying pyogenic process were key diagnostic features which enabled distinction of this neoplastic process from acute granylocytic leukemia and a leukemoid reaction. Other features included dysplastic granulocytes in various developmental stages, marginal anemia and hyperplastic bone marrow (myeloid elements). No blast crisis occurred. This dog was euthanatized in August 1975.
D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology; D004285:Dogs; D007951:Leukemia, Myeloid / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008297:Male; D013154:Spleen / Q000473:pathology