[A misleading diagnosis of ovarian tumours in a case of paramyeloblastosis (author's transl)].
A case is reported of bilateral ovarian tumours in a 44 year-old patient, who was submitted to total hysterectomy with removal of both appendages. Preoperative laboratory investigations had not yielded any useful information. Histologically, both ovaries showed replacement of the normal tissue by sheets of undifferentiated tumour cells. A sudden rise in temperature with rigors occurred on the 8th postoperative day, in conjunction with a considerable degree of anaemia, the appearance of ascites and a massive increase in size of the liver. Shortly afterwards, 50% of the peripheral leucocytes were found to be paramyeloblasts, the total leucocyte count being 4300. Sternal puncture confirmed the diagnosis of paramyeloblastosis, which proved rapidly fatal in spite of intensive therapy with corticosteroids, antibiotics and blood transfusions. The typical picture of paramyeloblastosis with tumour formation was observed on post-mortem examination, with leukaemic invasion of the liver, spleen, lymph glands and bone marrow.
D000328:Adult; D001344:Autopsy; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007951:Leukemia, Myeloid / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery
Diagnostisch irreführender Ovarialtumor