Comparative sensitivity of penicillinase producing Staphylococcus aureus to four cephalosporin antibiotics.
One hundred and seven strains of penicillinase producing Staphylococcus aureus were tested for their sensitivity to four cephalosporin antibiotics--cephalothin, cephaloridine, cephradine and cephalexin. All the strains were sensitive to these antibiotics. Cephaloridine was the most effective antibiotic and cephradine the least effective as measured by their minimum inhibitory concentration. Varying the inoculum size had no significant effect on the MIC of cephradine.
D002506:Cephalexin / Q000494:pharmacology; D002509:Cephaloridine / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology*; D002512:Cephalothin / Q000494:pharmacology; D002515:Cephradine / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010405:Penicillinase / Q000096:biosynthesis*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000201:enzymology
D002511:Cephalosporins; D010405:Penicillinase; D002515:Cephradine; D002509:Cephaloridine; D002506:Cephalexin; D002512:Cephalothin