title: Graded gastrectomy for duodenal ulcer -- a five-year prospective study.
abstract: One hundred and twelve consecutive patients selected for surgical treatment for duodenal ulcer disease were treated by a graded gastrectomy according to the Moynihan modification of the Billroth II partial gastrectomy. A large partial gastrectomy (R) (2/3-3/4 gastrectomy) was done in patients who after maximal stimulation with histamine showed a high acid output (MAO greater than 30 mEa/hr), and a small resection (r) (1/3-1/2 gastrectomy) in low secretors (MAO less than 30 mEq/hr). The material was prospectively controlled by admission to hospital at 3 months, 1 year and 5 years postoperatively. The preoperative values of MAO found in R and r were 42.8 and 21.5 mEq/hr (p less than 0.001), respectively. The postoperative MAO values at the 3-month control were 4.5 and 3.0 mEq/hr by R and r, respectively, which shows that the grading of resection had been successful. Atrophic gastritis increased in frequency from 4% at the time of operation to 72% at the 1-year control...
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000740:Anemia / Q000175:diagnosis; D001706:Biopsy; D001835:Body Weight; D002446:Celiac Disease / Q000175:diagnosis; D002648:Child; D004381:Duodenal Ulcer / Q000601:surgery*; D005260:Female; D005494:Folic Acid Deficiency / Q000175:diagnosis; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000379:methods*; D005750:Gastric Juice / Q000378:metabolism; D005753:Gastric Mucosa / Q000473:pathology; D005755:Gastrins / Q000097:blood; D006632:Histamine; D006801:Humans; D008297:Male; D008875:Middle Aged; D009664:Norway; D011178:Postgastrectomy Syndromes / Q000175:diagnosis; D011446:Prospective Studies; D012008:Recurrence; D014938:Work Capacity Evaluation
chemical_list: D005755:Gastrins; D006632:Histamine