title: [Left ventricular decompression by means of a paracorporeal transatrial ventriculo-aortic bypass pump: hemodynamics and long-term results (author's transl)].
abstract: Circulatory assist devices in current clinical use are analyzed. In this study the hemodynamic effects and long-term results with a paracorporeal ventriculo-aortic membrane pump with transatrial access to the left ventricular chamber are reported. The effectiveness of the pump was demonstrated by left ventricular decompression (-63%) and reduction of MVO2 (-41%), TTI (-71%), dp/dt max (-66%) and Q cor (-17%). These highly significant hemodynamic changes were, furthermore, confirmed by evaluation of the force-velocity relation (V max). In chronic experiments the bypass pump was implanted in 6 calves. The longest survival time was 18 days. 5 experiments were terminated on account of rupture of mechanical parts, one death was due to acute renal failure caused by emboli. Different bypes of ventriculo-aortic assist devices are discussed in regard to technical problems, hemodynamic efficiency and long-term results.
mesh_terms: D000818:Animals; D001011:Aorta / Q000502:physiology*; D001243:Assisted Circulation / Q000295:instrumentation; D002417:Cattle; D005260:Female; D006321:Heart / Q000502:physiology; D006439:Hemodynamics; D010101:Oxygen Consumption; D016276:Ventricular Function
vernacular_title: Untersuchungen zur Dekompression der linken Kammer mittels einer parakorporalen ventrikulo-aortalen Blutpumpe: Hämodynamik und Langzeitergebnisse