Oral health of patients with cystic fibrosis and their siblings.
Caries prevalence, oral hygiene index, submandibular gland hypertrophy, occlusion, dental hypoplasia, and staining of permanent teeth were evaluated in 63 patients with cystic fibrosis (CF) who were maintained on a regimen of broad-spectrum antibiotics and oral pancreatin, and the findings were compared with those of their near-aged siblings. Gland hypertrophy and dental staining were increased in patients with CF whereas caries was significantly decreased. No other significant differences were found.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000188:drug therapy*; D003731:Dental Caries / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D009909:Oral Health; D009910:Oral Hygiene; D010194:Pancreatin / Q000627:therapeutic use*; D013752:Tetracycline / Q000009:adverse effects; D014075:Tooth Discoloration / Q000209:etiology
D000900:Anti-Bacterial Agents; D010194:Pancreatin; D013752:Tetracycline