[Acute monoblastic leukemia. Clinical and therapeutic aspects in 20 cases].
Twenty cases of acute monoblastic leukemia are studied according to definite criterias: cytology, cytochemical staining, lysozyme production. The study points out the tumoral characters: hematodermy, gingivitis, central nervous system leukemia and the lack of important bone marrow incompetence. 47 per cent of complete remissions are obtained with daunorubicin, aracytin combination therapy. Other useful chemical agents, and prospects for maintenance therapy are discussed.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003561:Cytarabine / Q000627:therapeutic use; D003630:Daunorubicin / Q000627:therapeutic use; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D005260:Female; D005881:Gingiva / Q000473:pathology; D006801:Humans; D007008:Hypokalemia / Q000209:etiology; D007948:Leukemia, Monocytic, Acute / Q000097:blood / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009113:Muramidase / Q000378:metabolism; D011188:Potassium / Q000652:urine; D013163:Splenomegaly / Q000209:etiology
D000970:Antineoplastic Agents; D003561:Cytarabine; D009113:Muramidase; D011188:Potassium; D003630:Daunorubicin
Leucémie aiguë monoblastique. Aspects cliniques et thérapeutiques de 20 cas