Immune markers in adult acute leukemia.
Three cases of adult acute leukemia were examined for immunologic markers. Incubation of leukemic cells with anti-D (IgG)-coated erythrocytes was used for the identification of monocytes; sheep erythrocytes were employed for T-cells and fluorescein-conjugated anti-mixed immunoglobulins for B-cells. It was shown that IgG receptors (monocytes) were present on immature cells with predominant monocytic components; T- and B-cell markers were absent in the mono- and myelocytic leukemias.
D000328:Adult; D001666:Binding Sites, Antibody; D001853:Bone Marrow / Q000201:enzymology; D001854:Bone Marrow Cells; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006801:Humans; D007104:Immune Adherence Reaction; D007074:Immunoglobulin G / Q000032:analysis; D007948:Leukemia, Monocytic, Acute / Q000276:immunology* / Q000473:pathology; D007951:Leukemia, Myeloid / Q000276:immunology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000276:immunology; D011947:Receptors, Antigen, B-Cell / Q000032:analysis
D007074:Immunoglobulin G; D011947:Receptors, Antigen, B-Cell