Study by fluorescence microscopy of the effect of fluorescent whitening agents on the skin of mice.
Fluorescence microscopic studies of the skin of hairless mice showed that a fluorescent whitening agent (FWA) of the bis(phenyltriazolyl)stilbenedisulfonate type did not penetrate into the subepithelial layers (dermis and subcutaneous tissue) of the skin after cutaneous application.
D000818:Animals; D004396:Coloring Agents / Q000494:pharmacology*; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D008815:Mice, Inbred Strains; D008856:Microscopy, Fluorescence; D012867:Skin / Q000033:anatomy & histology / Q000187:drug effects*; D013267:Stilbenes / Q000494:pharmacology*; D013997:Time Factors
D004396:Coloring Agents; D013267:Stilbenes