Osteogenesis within polyethylene implants at fracture gaps.
Sterile 7 mm. polyethylene implants were implanted in standard 6 mm. bilateral midfibular fracture gaps in thirty rats (sixty defects), and six rats were used as controls with identical bilateral midfibular fracture gaps. Clinical, radiologic, and histologic studies at a 12-week interval revealed osteogenesis at internal and external surfaces of implants resulting in bony union; however, gaps without implants resulted in fibrous union and nonunion.
D000818:Animals; D001854:Bone Marrow Cells; D003238:Connective Tissue; D005360:Fibula / Q000166:cytology / Q000000981:diagnostic imaging / Q000293:injuries; D050723:Fractures, Bone / Q000601:surgery*; D005599:Fractures, Ununited / Q000517:prevention & control; D008297:Male; D010011:Osteocytes; D010012:Osteogenesis; D011095:Polyethylenes; D019736:Prostheses and Implants; D011859:Radiography; D051381:Rats
D011095:Polyethylenes