G banding in cytogenetic study of hemoblastoses.
G banding was used in the study of the karyotype of malignant cells in 10 patients: 5 with CML (3 in blastic crisis), 3 with AL and 2 with lymphosarcomas. In all cases of CML 22q-- (Ph1-chromosome) and 9q+ were present in leukemic cells. An i(17q) was observed in the karyotype of 2 out of 3 patients in blastic crisis of CML. In AL and lymphosarocmas small chromosome rearrangements were revealed and the origin of marker chromosomes could be established by the aid of G banding.
D000208:Acute Disease; D000328:Adult; D002869:Chromosome Aberrations; D002902:Chromosomes, Human, 16-18; D002904:Chromosomes, Human, 21-22 and Y; D002906:Chromosomes, Human, 6-12 and X; D003582:Cytogenetics; D005260:Female; D006801:Humans; D007621:Karyotyping; D007938:Leukemia / Q000235:genetics*; D007951:Leukemia, Myeloid / Q000235:genetics; D008213:Lymphocyte Activation; D008228:Lymphoma, Non-Hodgkin / Q000235:genetics*; D008297:Male; D008875:Middle Aged