Inability of low levels of sorbitol and mannitol to support caries activity in rats.
Under the environmental conditions of these experiments, neither 5 nor 10% sorbitol or mannitol in diets containing 62 or 57% corn starch, respectively, was capable of increasing the caries activity in rats above the level supported by a 67% starch diet. In contrast, 5% sucrose in the presence of 62% corn starch caused a slight increase and 10% sucrose in the presence of 57% starch caused a significant increase in caries activity beyond that observed when the diet containing 67% starch as the only carbohydrate was fed.
D000818:Animals; D001835:Body Weight; D003731:Dental Caries / Q000209:etiology*; D004040:Dietary Carbohydrates; D005260:Female; D008353:Mannitol / Q000494:pharmacology*; D051381:Rats; D013012:Sorbitol / Q000494:pharmacology*; D013213:Starch; D013395:Sucrose / Q000494:pharmacology
D004040:Dietary Carbohydrates; D008353:Mannitol; D013012:Sorbitol; D013395:Sucrose; D013213:Starch