[Inhibition effects of extracellular glucosyltransferase from Streptococcus mutans].
The extracellular, gel-electrophoretically pure glucosyl transferase (GT) of Streptococcus mutans st.227 was incubated with various inhibitors and the synthetic product quantitatively determined. The GT activity was increased with low urea concentration (0.3 - 1.2 M) and inhibited with higher urea molarity. Sodium dodecyl sulfate and quarternary ammonium compounds (detergents) have a clear inhibiting effect starting with 0.005%, while NaF, KSCN, ethylene diamine tetra-acetic acid and sugar alcohols do not have any influence.
D004791:Enzyme Inhibitors; D005110:Extracellular Space; D005964:Glucosyltransferases; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology; D013291:Streptococcus / Q000201:enzymology*; D013295:Streptococcus mutans / Q000201:enzymology*
D004791:Enzyme Inhibitors; D000644:Quaternary Ammonium Compounds; D005964:Glucosyltransferases
Inhibitionseffekte der extrazellulären Glucosyltransferase von S. mutans