title: Some clinical observations on the effect of an implant of oestradiol benzoate in brood mares.
abstract: The clinical effects and therapeutic value of a 500 mg implant of oestradiol benzoate was observed in thirty-nine Thoroughbred brood mares showing various abnormalities of the ovary and/or the reproductive tract. Sixteen similarly affected, untreated mares acted as controls. The implant was inserted during the early part of the normal anoestrous period and was removed 6 to 10 weeks later. The conception rate among the treated group (59%) during the onset of the ensuing breeding season was significantly higher (P less than 0-02) than that in the control group. The value of this form of treatment in septic endometritis and as an anabolic aid in cases of immaturity is also discussed.
mesh_terms: D000818:Animals; D004343:Drug Implants; D004716:Endometritis / Q000188:drug therapy / Q000662:veterinary; D004958:Estradiol / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use*; D004971:Estrus / Q000187:drug effects; D005260:Female; D005306:Fertilization; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D007247:Infertility, Female / Q000188:drug therapy / Q000662:veterinary*; D010049:Ovarian Diseases / Q000188:drug therapy / Q000662:veterinary; D011247:Pregnancy; D013997:Time Factors
chemical_list: D004343:Drug Implants; D004958:Estradiol