title: On the correlation of chromosome number and DNA content in HeLa cell clones.
abstract: Chromosome number and nuclear DNA content of two cloned HeLa cell lines were analysed by quantitative Feulgen reaction microspectrophotometry, ultra-rapid microfluorometry and chromosome counting. These cell clones revealed corresponding alterations in their chromosome number and nuclear DNA amount. The results support the hypothesis that a constant relationship exists between both chromosome number and nuclear DNA content in these clonal population.
mesh_terms: D002452:Cell Count; D002455:Cell Division; D002875:Chromosomes / Q000032:analysis*; D002999:Clone Cells; D004273:DNA, Neoplasm / Q000032:analysis*; D005470:Fluorometry; D006367:HeLa Cells / Q000032:analysis*; D006801:Humans; D006868:Hydrolysis; D007621:Karyotyping; D013053:Spectrophotometry; D013696:Temperature
chemical_list: D004273:DNA, Neoplasm