Amoeboid movement configuration and mitotic indices of lymphoid cells from children with acute lymphoblastic leukaemia.
Bone marrow smears from 21 untreated patients with ALL have been morphologically analysed. There was a positive correlation between the percentages of lymphoid cells with amoeboid movement configuration (AMC) and the mitotic indices. A high proportion of cells with AMC seems to indicate a more favourable prognosis in spite of differences in subsequent treatment. It is suggested that studies of the incidence of AMC may serve as a prognostic tool in ALL.
D000293:Adolescent; D002465:Cell Movement; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007945:Leukemia, Lymphoid / Q000175:diagnosis* / Q000473:pathology; D008214:Lymphocytes; D008297:Male; D008938:Mitosis; D008940:Mitotic Index; D011379:Prognosis