Experimental foreign body reactions to toothpaste abrasives.
Some clinical oral foreign body reactions have been reviewed. The testing of the foreign body potential of substances used as abrasives in toothpastes has shown a number to be capable of this. The clinical implications are briefly discussed. The initial studies were conducted when the author was on the faculty of the School of Dentistry, University of Birmingham, England.
D000818:Animals; D002642:Chick Embryo; D006224:Cricetinae; D003802:Dentifrices / Q000009:adverse effects*; D005321:Extraembryonic Membranes / Q000187:drug effects; D006168:Guinea Pigs; D051381:Rats; D012867:Skin / Q000187:drug effects; D012871:Skin Diseases / Q000139:chemically induced; D014072:Tooth Abrasion; D014100:Toothpastes / Q000009:adverse effects*
D003802:Dentifrices; D014100:Toothpastes