Leukemia of BALB/c mice induced by cellfree filtrate from transplantable Thurzo--Svec rat leukemia.
Leukemia was produced in adult BALB/c mice inoculated with cellfree filtrate derived from cells of transplantable Thurzo-Svec rat leukemia. The leukemogenic activity of 20% filtrates was 10(8) ID 50 per ml. Leukemia induced in mice with rat materials was serially transplantable by cellfree filtrates of leukemic tissues and plasma to the same strain of mice.
D000818:Animals; D002474:Cell-Free System; D007942:Leukemia, Experimental / Q000635:transmission*; D007951:Leukemia, Myeloid / Q000635:transmission*; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D051381:Rats; D014183:Transplantation, Heterologous