title: [The use of a bactericidal substance as medication in the indirect capping of healthy dentin].
abstract: An association of trimethoprim and sulphamethoxazol (Bactrim, Roche) was employed in the indirect capping of healthy teeth in the dog. Tetracycline labelling showed dentinogenesis in these teeth and comparison was made with the controls, A quantitative and qualitative change in dentinogenesis was noted below the control cavities. This alteration was less marked in Bactrim-treated teeth. It is deduced, therefore, that the operations involved in the preparation and filling of cavities in healthy teeth leads to pulp damage that can be partly prevented by using a bactericide.
mesh_terms: D000818:Animals; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D002266:Carboxymethylcellulose Sodium; D003785:Dental Pulp Capping; D003804:Dentin / Q000187:drug effects; D004285:Dogs; D004338:Drug Combinations; D006801:Humans; D013420:Sulfamethoxazole / Q000627:therapeutic use*; D014295:Trimethoprim / Q000627:therapeutic use*
chemical_list: D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D014295:Trimethoprim; D013420:Sulfamethoxazole; D002266:Carboxymethylcellulose Sodium
vernacular_title: Sull'impiego di una sostanza battericida come medicamento nell'incappucciamento indiretto su dentina sana