Failure of the opiate antagonist naloxone to modify hypnotic analgesia.
Hypnotic analgesia in some respects resembles opiate analgesia. We tested the hypothesis that some features of hypnotic analgesia are mediated through neuronal pathways activating specific opiate receptors in brain. The opiate antagonist naloxone had no effect on hypnotic analgesia in three subjects. Thus, the hypothesis was not confirmed.
D005260:Female; D006801:Humans; D006991:Hypnosis, Anesthetic; D007511:Ischemia; D008297:Male; D009270:Naloxone / Q000494:pharmacology*; D010146:Pain
D009270:Naloxone