Radiation therapy in the treatment of leukemic infiltrates of the testes.
Testicular infiltration developed in 6 of 56 boys with lymphoblastic leukemia. All exhibited platelet counts under 100,000, indicating poor prognosis. Patients were treated with vincristine, prednisone, and craniomemingeal prophylaxis (2,400 rads/12 fx) extending to the C2 level. Only 3 patients did not suffer recurrence of testicular disease during their multiple leukemic relapses. Alternate treatment courses are suggested.
D000208:Acute Disease; D001932:Brain Neoplasms / Q000532:radiotherapy; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000532:radiotherapy*; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D011379:Prognosis; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D013921:Thrombocytopenia / Q000150:complications; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine; D011241:Prednisone