[Congenital leucosis with unusual involvement of the brain(author's transl)].
A case of congenital paraleucoblast-leucosis is reported. The diagnosis rested on pronounced infiltrations of the skin and leucemic signs in blood and bone marrow. The child died on the 20th day after developing signs of bleeding and cerebral involvement. At necropsy leucotic infiltration was found in may organs, mainly in pancreas, skin and bone marrow. The most prominent findings and cause of death were diffuse hemorrhagic foci with a high proportion of leucemic cells in the brain and cerebellum.
D000208:Acute Disease; D001344:Autopsy; D001853:Bone Marrow / Q000473:pathology; D001854:Bone Marrow Cells; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000151:congenital* / Q000473:pathology; D002528:Cerebellar Neoplasms / Q000150:complications; D002543:Cerebral Hemorrhage / Q000150:complications; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007945:Leukemia, Lymphoid / Q000150:complications / Q000151:congenital* / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000150:complications; D012878:Skin Neoplasms / Q000150:complications
Angeborene Leukose mit ungewöhnlichem Hirnbefall