[Human non-epithelial tumors in "nude" mice: morphology and growth characteristics].
Morphology and growth characteristics of an osteosarcoma and a glioblastoma are described after direct transplantation in nude (thymusless) mice. In osteosarcoma neither characteristic had changed after 14 months' observation. In contrast, some of the glioblastoma transplants (22 months' observation) showed dedifferentiation of morphology and grew faster than others derived from the same biopsy. The possible reasons for the different growth pattern of the two tumors are discussed.
D000818:Animals; D005260:Female; D005910:Glioma / Q000473:pathology*; D006801:Humans; D008297:Male; D051379:Mice; D008819:Mice, Nude; D009361:Neoplasm Invasiveness; D009368:Neoplasm Transplantation; D012516:Osteosarcoma / Q000473:pathology*
Menschliche nicht-epitheliale Tumoren bei "nude" Mäusen: Morphologie und Wachstumscharakteristika