title: Urinary dimethyltryptamine and psychiatric symptomatology and classification.
abstract: The excretion of dimethyltryptamine (DMT) was studied amongst 122 recently admitted psychiatric patients and 20 normal subjects. DMT was detected in the urine of 47% of those diagnosed by their psychiatrists as schizophrenic, 38% of those with other non-affective psychoses, 13% of those with affective psychoses, 19% of those with neurotic and personality disorders and 5% of normal subjects. Ninety-nine patients were interviewed in a semi-standardized fashion, and also categorized according to a variety of operational definitions of the psychoses. The operational definitions failed to reveal any group significantly more correlated with urinary DMT than a hospital diagnosis of schizophrenia, but a discriminant function analysis of symptomatology could be used to define a group of 21 patients of whom 15 (71%) excreted detectable DMT. There was a general relationship between psychotic symptoms and urinary DMT, but specifically schizophrenic symptoms did not appear to be major determinants of DMT excretion.
mesh_terms: D000293:Adolescent; D000328:Adult; D000342:Affective Symptoms / Q000652:urine; D000368:Aged; D003702:Delusions / Q000652:urine; D005260:Female; D006212:Hallucinations / Q000652:urine; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000652:urine*; D008875:Middle Aged; D009043:Motor Activity; D004130:N,N-Dimethyltryptamine / Q000652:urine*; D009497:Neurotic Disorders / Q000652:urine; D010259:Paranoid Disorders / Q000652:urine; D010554:Personality Disorders / Q000652:urine; D011618:Psychotic Disorders / Q000652:urine; D012559:Schizophrenia / Q000652:urine; D014363:Tryptamines / Q000652:urine*; D014705:Verbal Behavior
chemical_list: D014363:Tryptamines; D004130:N,N-Dimethyltryptamine