[Changes of the phosphatides and their fatty acids in the retina and in the fasciculus opticus after retinal detachment: investigations of human and animal retinae (author's transl)].
In this study the effect of an experimentally provoked retinal detachment on the pattern of the phosphatides and fatty acids of the retina and the optic nerve of adult rabbits was investigated. The analysis was performed one month, and 4 months after the operation, and the values were related to the findings in control animals of the same age, and of the age of one day and 30 days respectively. In this way changes in the total lipide, in the phosphatides and in their fatty acids could be revealed, with a tendency towards the developmental stage of the 20th up to the 30th day of life. Between retina and optic nerve no difference was found neither temporally nor regarding the quantitative reaction. In the detached human retinae the same reactions can be proved as in the animal experiment. The relationship of these findings to the recovery of the operatively reatached human retina is discussed.
D000328:Adult; D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D005227:Fatty Acids / Q000378:metabolism*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009900:Optic Nerve / Q000254:growth & development / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D011817:Rabbits; D012160:Retina / Q000254:growth & development / Q000378:metabolism*; D012163:Retinal Detachment / Q000378:metabolism* / Q000601:surgery; D013997:Time Factors
D005227:Fatty Acids; D010713:Phosphatidylcholines; D010743:Phospholipids
Veränderungen der Phosphatide und ihrer Fettsäuren in der Netzhaut und im Fasc. opticus bei Ablatio retinae: Analysen von menschlichem und tierischem Untersuchungsgut