title: Shigella strains associated with infantile diarrhea in the Kaohsiung area.
abstract: In 1969 and 1974, 375 Shigella strains were isolated in the Kaohsiung area, and their serotypes and in vitro susceptibility to antimicorbial agents were studied. In 1969, 249 (16.2%) strains were isolated from 1,476 specimens collected from infantile and young children dirrheal cases, whereas 126 strains (11.6%) were isolated from 1,086 specimens in 1969. The isolation rates were higher in May (21.2%), October (20.8%), April (20.6%), August (19.7), November (18.8%) and January (18.5%), than in other months (10.2%-18.0%). Higher incidences of shigellosis appeared in May (22.3%) and April (17.9%) than in the other months during 1974. Shigella sonnei and Shigella flexneri type 2 were most predominant and there was a tendency of increase in number for the former in 1974. From the colicine typing of S. sonnei, it was found that type 8 (40.6%), type 6 (23.4%), and type 12 (17.2%) were the commonly occurring strains associated with the infantile diarrheal disease in the Kaohsiung area. Susceptibility study showed that the resistant rates of S. flexneri to chlroamphenicol (85.5%), streptomycin (81.9%), and tetracycline (61.3%) were much higher than to ampicillin (16.1%), nalidixic acid (14.6%), colistin (4.2%), kanamycin (4.2%), gentamicin (2.8%), cephaloridine (2.4%), and frazolidone (0%). Resistant rates of S. sonnei to 10 antimicrobial agents were as follows: chloramphenicol, 85.9%; tetracycline, 70.2%; streptomycin, 69.9%; nalidixic acid, 16.4%; ampicillin, 13.3%; colistin, 6.3%; kanamycin, 3.9%; gentamicin, 2.5%; cephaloridine, 0%; and frazolidone, 0%.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003968:Diarrhea, Infantile / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D012703:Serotyping; D012760:Shigella / Q000187:drug effects / Q000302:isolation & purification*; D012761:Shigella boydii / Q000302:isolation & purification; D012762:Shigella dysenteriae / Q000302:isolation & purification; D012764:Shigella sonnei / Q000302:isolation & purification; D013624:Taiwan; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents