Does pentagastrin supress secretin induced pepsin secretion in Heidenhain pouch dogs?
Secretin-stimulated pepsin secretion from Heidenhain pouches was significantly depressed by concomitant pentagastrin. Pentagastrin by itself was without effect on pouch pepsin. Methacholine, on the other hand, did not antagonize secretin-stimulated pouch pepsin.
D000818:Animals; D004285:Dogs; D005753:Gastric Mucosa / Q000378:metabolism*; D008688:Methacholine Compounds / Q000494:pharmacology; D010418:Pentagastrin / Q000494:pharmacology*; D010434:Pepsin A / Q000378:metabolism*; D012633:Secretin / Q000037:antagonists & inhibitors*; D013270:Stomach / Q000187:drug effects
D008688:Methacholine Compounds; D012633:Secretin; D010434:Pepsin A; D010418:Pentagastrin