[Clinical study on five depot neuroleptics.  Comparison of effective profiles of fluphenazinedecanoate, fluspirilene, penfluridol, perphenazine-enanthate and pipothiazinepalmitate].
Five depot neuroleptics (fluphenazinedeconoate, fluspirilene, pipothiazinepalmitate, penfluridol and perphenazine-enanthate) were compared based on clinical trials in subacute and chronic schizophrenic patients.  The psychopathological symptoms were documented by means of the AMP-system.  Statistical analyses showed several differences between the effects of the five substances.  The AMP-system proved a useful instrument to differentiate similar drugs.
D000284:Administration, Oral; D001714:Bipolar Disorder / Q000188:drug therapy; D002389:Catatonia / Q000188:drug therapy; D002986:Clinical Trials as Topic; D003692:Delayed-Action Preparations; D004341:Drug Evaluation; D005260:Female; D005464:Fluorobenzenes / Q000627:therapeutic use; D005476:Fluphenazine / Q000009:adverse effects / Q000627:therapeutic use; D006212:Hallucinations / Q000188:drug therapy; D006791:Hostility; D006801:Humans; D006846:Hydrocarbons, Halogenated / Q000627:therapeutic use; D006998:Hypochondriasis / Q000188:drug therapy; D007273:Injections, Intramuscular; D008722:Methods; D010259:Paranoid Disorders / Q000188:drug therapy; D010546:Perphenazine / Q000009:adverse effects / Q000627:therapeutic use; D010880:Piperidines / Q000627:therapeutic use; D012559:Schizophrenia / Q000188:drug therapy*; D013141:Spiro Compounds / Q000627:therapeutic use; D013449:Sulfonamides / Q000627:therapeutic use; D013997:Time Factors; D014149:Tranquilizing Agents / Q000009:adverse effects / Q000627:therapeutic use*
D003692:Delayed-Action Preparations; D005464:Fluorobenzenes; D006846:Hydrocarbons, Halogenated; D010880:Piperidines; D013141:Spiro Compounds; D013449:Sulfonamides; D014149:Tranquilizing Agents; D010546:Perphenazine; D005476:Fluphenazine
Klinische Prüfung von fünf Depotneuroleptika. Vergleich der Wirkungsprofile von Fluphenazindecanoat, Fluspirilen, Penfluridol, Perphenazinoenanthat und Pipothiazinpalmitat