title: [Enhancement of the cooperation of T- and B-lymphocytes in the immune response and the induction of antibody production in B-mice].
abstract: The effect of poly-4-vinylpyridine and polyacrilic acid on production of antibodyforming cells to the sheep red blood cells in in vivo mixed cultures of T- and B-lymphocytes involved an obvious increase of the immune response. To a lesser extent theimmune response was increased in B-lymphocyte cultures, and no such effect was observed in T-lymphocyte cultures. The poly-4-vinlpyridine and polyacrilic acid were concluded to enhance cooperation between T- and B-lymphocytes and, probably, to replacethe T-lymphocytes function in B-mice.
mesh_terms: D000179:Acrylates / Q000494:pharmacology; D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology*; D001853:Bone Marrow / Q000276:immunology; D001854:Bone Marrow Cells; D002478:Cells, Cultured; D004912:Erythrocytes / Q000276:immunology; D007111:Immunity, Cellular / Q000187:drug effects; D007112:Immunity, Maternally-Acquired; D007114:Immunization; D011145:Polyvinyls / Q000494:pharmacology; D011725:Pyridines / Q000494:pharmacology; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D013997:Time Factors
chemical_list: D000179:Acrylates; D011145:Polyvinyls; D011725:Pyridines
vernacular_title: Usilenie kooperatsii T- i B-limfotsitov v immunom otvete i induktsiia antitelogeneza u B-mysheĭ