The effects of chemotherapeutics on the species streptococcus in vitro.
The authors studied the sensitivity of some rather recent products--flucloxacillin, doxycyclin, clindamycin and cotrimoxazol--in correlation with classical penicillin. If therapy by means of classical penicillins is unsuitable, clindamycin and the semi-synthetic penicillin flucloxacillin appear to be a further alternative and the most suitable chemotherapeutic in streptococcal infections.
D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002981:Clindamycin / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004318:Doxycycline / Q000494:pharmacology; D005436:Floxacillin / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000494:pharmacology*; D013045:Species Specificity; D013290:Streptococcal Infections / Q000188:drug therapy; D013291:Streptococcus / Q000187:drug effects*; D013292:Streptococcus agalactiae / Q000187:drug effects; D013297:Streptococcus pyogenes / Q000187:drug effects; D013420:Sulfamethoxazole / Q000494:pharmacology / Q000627:therapeutic use; D014295:Trimethoprim / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D010406:Penicillins; D002981:Clindamycin; D005436:Floxacillin; D014295:Trimethoprim; D013420:Sulfamethoxazole; D004318:Doxycycline