title: Tuberculosis in Black children. A retrospective analysis of severe cases.
abstract: A retrospective study of 176 Black children requiring hospital treatment for tuberculosis showed that infants and children under the age of 3 years are especially susceptible. Extensive and disseminated disease is usually present at the time of diagnosis, which was sometimes made difficult by a low tuberculin sensitivity caused by malnutrition, measles, or overwhelming infection. Almost a quarter of the patients had received BCG. Approximately half the patients had disseminated disease; of these, 40% had tuberculous meningitis and 12% died, whereas the mortality of those with localised disease was 3%.
mesh_terms: D001741:Black or African American; D000367:Age Factors; D001500:BCG Vaccine; D044383:Black People; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009748:Nutrition Disorders / Q000150:complications; D012189:Retrospective Studies; D013019:South Africa; D014374:Tuberculin Test; D014390:Tuberculosis, Meningeal / Q000401:mortality; D014391:Tuberculosis, Miliary / Q000401:mortality; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000175:diagnosis / Q000517:prevention & control
chemical_list: D001500:BCG Vaccine