Wound infections due to Bacteroides fragilis following intestinal surgery.
Ninety-six wound infections due to Bacteroides fragilis occurring after intestinal surgery are described. Most infections followed appendicectomy or colectomy for diverticulitis. B. fragilis was isolated in pure growth from 47 per cent of infections, and in mixed culture the other common bacteria were Klebsiella spp., Escherichia coli and Enterobacter spp. Fifty-three per cent of the infections responded rapidly to either non-specific measures or antibiotic therapy, but 47 per cent of patients developed complications, usually abscess formation. The successful isolation of bacteroides from clinical material requires special precautions. The specimen for bacteriological examination must be sent to the laboratory in a transport medium which maintains an anaerobic environment and the culture techniques must include a selective agar for the isolation of anaerobic bacteria. The role of antibiotic therapy in preventing postoperative wound infection after intestinal surgery is discussed. Bacteroides has an unusualy pattern of antibiotic susceptibility and it is essential that an effective antibiotic such as lincomycin is included in the treatment of infection originating from the intestinal tract.
D000038:Abscess / Q000209:etiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001062:Appendectomy; D001431:Bacteriological Techniques; D001439:Bacteroides / Q000302:isolation & purification; D001442:Bacteroides Infections / Q000150:complications / Q000188:drug therapy; D003082:Colectomy; D004238:Diverticulitis / Q000601:surgery; D006801:Humans; D007422:Intestines / Q000601:surgery*; D008034:Lincomycin / Q000627:therapeutic use; D013530:Surgical Wound Infection / Q000150:complications / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D008034:Lincomycin