Chromosomal proteins in human B and T lymphocytes.
Histones and non-histone chromosomal proteins were characterized in B and T human lymphocytes by means of polyacrylamide disc gel electrophoresis. It was found that while histones do not present appreciable differences in the two examined populations, non-histone chromosomal proteins exhibit distinct electrophoretic profiles. Low molecular weight proteins predominate in B lymphocytes whereas high and intermediate proteins are largely represented in T lymphocytes. The latter proteins may be related to the capability of these resting cells to proliferate under appropriate antigenic stimuli.
D001402:B-Lymphocytes / Q000032:analysis*; D002868:Chromosomal Proteins, Non-Histone / Q000032:analysis*; D002875:Chromosomes / Q000032:analysis*; D004589:Electrophoresis, Disc; D006657:Histones / Q000032:analysis*; D006801:Humans; D008970:Molecular Weight; D013601:T-Lymphocytes / Q000032:analysis*
D002868:Chromosomal Proteins, Non-Histone; D006657:Histones