Deviating flux ratios for Na+ in ouabain-treated frog skin.
Unidirectional Na+ fluxes across ouabain-treated frog skins were measured at different applied voltages. The calculated influx/efflux ratios appear to deviate markedly from Ussing's flux-ratio equation. This means that interactions of Na+ ions with some component in the system occur. Possible mechanisms, responsible for this phenomenon, are indicated.
D000818:Animals; D001001:Anura; D004058:Diffusion; D010042:Ouabain / Q000494:pharmacology*; D011896:Rana temporaria; D012867:Skin / Q000187:drug effects* / Q000378:metabolism; D012964:Sodium / Q000378:metabolism*
D010042:Ouabain; D012964:Sodium