title: Metrifonate in urinary schistosomiasis. A field trial in northern Nigeria.
abstract: A field trial of metrifonate in the form of Bilarcil tablets (Bayer) was carried out in 39 northern Nigerian schoolchildren heavily infected with Schistosoma haematobium. Three oral doses of 7.5 mg/kg were given at four-week intervals. The drug proved effective (mean reduction in egg counts eight weeks after completion of treatment 94.5%) and was excellently tolerated. Its use on a larger scale is suggested.
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D002648:Child; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010270:Parasite Egg Count; D012548:Schistosoma haematobium; D012552:Schistosomiasis / Q000188:drug therapy*; D014236:Trichlorfon / Q000008:administration & dosage*; D014556:Urine / Q000469:parasitology
chemical_list: D014236:Trichlorfon