[Immunosuppressive therapy in pure red cell aplasia].
Acquired erythroblastic aplasia of adults is a rare disease characterised by the absence of red cell precursors in the bone marrow. In a 34-year-old female patient the disease has been known for seven years. A partial remission had at first been achieved with glucocorticoids but regular transfusions had been necessary since 1971. Treatment with cyclophosphamide produced a remission which has lasted for over twelve months up to now. Histology of the bone marrow biopsy shows the appearance of active erythropoiesis after cyclophosphamide treatment which reflects well the clinical course.
D000328:Adult; D045930:Anabolic Agents / Q000627:therapeutic use; D000741:Anemia, Aplastic / Q000188:drug therapy* / Q000276:immunology; D000917:Antibody Formation; D000961:Antilymphocyte Serum / Q000627:therapeutic use; D001379:Azathioprine / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D015122:Mercaptopurine / Q000627:therapeutic use; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D011379:Prognosis; D012075:Remission, Spontaneous; D013601:T-Lymphocytes / Q000276:immunology; D013739:Testosterone / Q000627:therapeutic use; D014805:Vitamin B 12 / Q000627:therapeutic use
D045930:Anabolic Agents; D000961:Antilymphocyte Serum; D007166:Immunosuppressive Agents; D013739:Testosterone; D003520:Cyclophosphamide; D015122:Mercaptopurine; D001379:Azathioprine; D014805:Vitamin B 12; D011241:Prednisone
Immunsuppressive Therapie bei Erythroblastophthise