Effect of hypothermia and endotoxin on phagocytosis.
Experiments with colloidal 198Au indicated that gold clearance highly decreased in rabbits cooled to 29-30 degrees C. The capacity of storing colloidal gold decreased especially in the spleen and liver. Endotoxin reduced the gold clearance in normothermic rabbits; the decrease was more marked in hypothermic animals.
D000311:Adrenal Glands / Q000502:physiology; D000818:Animals; D004731:Endotoxins / Q000494:pharmacology*; D004926:Escherichia coli; D005260:Female; D006048:Gold Colloid, Radioactive; D007036:Hypothermia, Induced; D007275:Injections, Intravenous; D007668:Kidney / Q000502:physiology; D008099:Liver / Q000502:physiology; D008168:Lung / Q000502:physiology; D008297:Male; D009928:Organ Specificity; D010587:Phagocytosis / Q000187:drug effects; D011817:Rabbits; D013154:Spleen / Q000502:physiology
D004731:Endotoxins; D006048:Gold Colloid, Radioactive