Migratory patterns of B lymphocytes. III. Inhibition of splenic follicular localization of transferred chicken bursa cells by preincubation with anti-Ig-1.
Homing of 3-H-adenosine-labeled bursa cells to follicles in the chickens spleen was greatly reduced by prior incubation of the transferred cells with rabbit anti-chicken-immunoglobulin sera. This effect was transient, being present 6 hr after cell transfer but gone by 18 hr, when incubation was at 0 degreesC without complement. The inhibition persisted until at least 18 hr after incubation at 37 degrees C with complement.
D000042:Absorption; D000241:Adenosine / Q000378:metabolism; D000818:Animals; D001345:Autoradiography; D001402:B-Lymphocytes / Q000276:immunology*; D002060:Bursa of Fabricius / Q000166:cytology; D002465:Cell Movement; D002645:Chickens; D003165:Complement System Proteins; D006168:Guinea Pigs / Q000276:immunology; D007106:Immune Sera; D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D008099:Liver / Q000166:cytology; D008168:Lung / Q000166:cytology; D011828:Radiation Chimera; D013154:Spleen / Q000166:cytology*; D013950:Thymus Gland / Q000166:cytology; D014316:Tritium
D007106:Immune Sera; D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D014316:Tritium; D003165:Complement System Proteins; D000241:Adenosine