Livedo vasculitis (the vasculitis of atrophie blanche). Immunohistopathologic study.
Hyalinizing segmental vasculitis or livedo vasculitis (atrophie blanche) is a clinical entity with a distinctive immunohistopathologic morphology that can be distinguished from other forms of cutaneous vasculitis by histologic and direct immunofluorescent studies. Our studies showed that immunoglobulins and complement components (C-1g, C-3, and properdin) were localized in diseased vessel walls, suggesting an immune pathogenesis.
D001284:Atrophy; D001706:Biopsy; D001808:Blood Vessels / Q000276:immunology; D003165:Complement System Proteins / Q000032:analysis; D005121:Extremities / Q000098:blood supply; D005337:Fibrin / Q000032:analysis; D005455:Fluorescent Antibody Technique; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D011414:Properdin / Q000032:analysis; D012867:Skin / Q000473:pathology; D014652:Vascular Diseases / Q000276:immunology* / Q000473:pathology
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011414:Properdin; D005337:Fibrin; D003165:Complement System Proteins