Aspects of lymphocyte function in Behçet's disease.
Aspects of lymphocyte function were investigated, in vitro, in nine patients with active Behçet's disease. The rosette formation technique revealed a slight decrease in number of T lymphocytes and more so of B lymphocytes. In spite of their low number, the transformation of the T lymphocytes in response to mitogens did not show a significant difference from that of normal controls. This may indicate a hyperreactivity, and in two instances a spontaneous blastogenesis prior to addition of mitogens, was also noted. The immunoglobulins and complement levels in serum were within normal limits.
D001402:B-Lymphocytes / Q000276:immunology; D001528:Behcet Syndrome / Q000276:immunology*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology