Antibodies to thymocytes in sera of normal controls and of patients with schizophrenia.
The sera from normal healthy individuals and from patients with schizophrenia were tested for cytotoxic antibodies against thymic antigens located on thymocytes. It was found that the sera from schizophrenics do not show higher cytotoxicity to mouse and rabbit thymocytes than the sera from normal controls. Furthermore, absorption of sera with adult mouse thymocytes and brain failed to show any difference between the sera from these two groups of subjects.
D000818:Animals; D001323:Autoantibodies / Q000032:analysis*; D001921:Brain / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D005476:Fluphenazine / Q000494:pharmacology; D006801:Humans; D051379:Mice; D011817:Rabbits; D012559:Schizophrenia / Q000276:immunology*; D013045:Species Specificity; D013601:T-Lymphocytes / Q000276:immunology*
D001323:Autoantibodies; D005476:Fluphenazine