In vitro proliferative reactions by lymphocytes from both responder and "low" responder mice to (T,G)-A--L.
In summary (T,G)-A--L can induce specific in vitro lymphoproliferative reactions in LNC from immunized mice. From 3-8 weeks after immunization lymphocytes from responder mice react to a much greater degree than from low responders. These proliferative reactions are not specifically enhanced by supernatants of "educated" T cells. However, 2 to 3 months after immunization the lymphoproliferative response of the low responders rises to the same level as that of responder mice.
D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology*; D000941:Antigens; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis; D005796:Genes; D007156:Immunologic Memory; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000378:metabolism; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D010455:Peptides / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D000941:Antigens; D010455:Peptides; D004247:DNA