Effect of native levan on homograft rejection in mice.
The effect of high-molecular-weight levan on skin graft rejection was studied. Daily ip administration of 15-30 mg levan was shown to delay rejection in Balb/c and C57BL recipient mice. An increase in MST value by 3.6 days was obtained in Balb/c mice and of 5.6 days for C57BL.
D000818:Animals; D005632:Fructose / Q000494:pharmacology; D006084:Graft Rejection; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008970:Molecular Weight; D011134:Polysaccharides / Q000494:pharmacology*; D016038:Skin Transplantation; D013997:Time Factors; D014184:Transplantation, Homologous
D011134:Polysaccharides; D005632:Fructose