[Coupled use of chromatography and acrylamide-agarose gel electrophoresis in the study of polymeric forms of paraproteins].
A study of the physical properties of paraprotein required until now, the use of fairly complicated techniques, such as analytical ultracentrifugation. The use of chromatography on acrylamide agar pearls and electrophoresis on indubiose plates, coupled with the classical techniques of electrophoresis and immunoelectrophoresis, permitted a more simple approach to these problems. The study of IgA paraproteins in several polymerised forms, is an example of the possibilities of this new method of investigation.
D002845:Chromatography; D003545:Cysteine / Q000494:pharmacology; D004586:Electrophoresis / Q000379:methods; D006801:Humans; D007122:Immunoelectrophoresis; D007070:Immunoglobulin A / Q000032:analysis*; D010266:Paraproteins / Q000032:analysis*; D011108:Polymers
D007070:Immunoglobulin A; D010266:Paraproteins; D011108:Polymers; D003545:Cysteine
Utilisation couplée de la chromatographie et de l'électrophorèse sur gels d'acrylamide-agarose pour l'étude des formes polymériques des paraprotéines