Influence of tetrahydro-aminacrine on muscle pains after suxamethonium.
The incidence and severity of muscle pains were investigated in patients who had been given suxamethonium and thiopentone anesthesia for bronchoscopy. Group I patients received no other drugs. Groups II and III received d-tubocurarine and THA respectively before suxamethonium. Administration of these drugs resulted in a highly significant reduction in the incidence of severe and moderate pains. The use of d-tubocurarine necessitated a significantly greater amount of suxamethonium to maintain paralysis.
D000166:Acridines / Q000627:therapeutic use*; D000588:Amines / Q000627:therapeutic use; D001999:Bronchoscopy; D002986:Clinical Trials as Topic; D006801:Humans; D008875:Middle Aged; D009135:Muscular Diseases / Q000139:chemically induced / Q000517:prevention & control*; D010149:Postoperative Pain / Q000139:chemically induced / Q000517:prevention & control*; D013390:Succinylcholine / Q000008:administration & dosage / Q000009:adverse effects*; D013874:Thiopental / Q000008:administration & dosage; D014403:Tubocurarine / Q000627:therapeutic use
D000166:Acridines; D000588:Amines; D013390:Succinylcholine; D013874:Thiopental; D014403:Tubocurarine