Cold agglutinin formation in patients undergoing haemodialysis.  A possible relationship to dialyser re-use.
Cold agglutinins with anti-N characteristics were shown to develop in as short a time as four months in patients on home dialysis.  It appeared that the development of such antibodies is related to dialyser re-use.  Those who were treated without re-using their dialyser did not develop these antibodies.  Anti-N may cause early graft failure associated with agglutination in a cold allograft.  Moreover, if these antibodies develop in patients on dialysis there may be problems with extracorporeal dialysis and blood transfusion.
D000373:Agglutinins; D000917:Antibody Formation; D001323:Autoantibodies; D001803:Blood Transfusion; D003080:Cold Temperature; D005260:Female; D006437:Hemodialysis, Home / Q000009:adverse effects*; D006760:Hospitalization; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D006435:Renal Dialysis; D013997:Time Factors; D014184:Transplantation, Homologous
D000373:Agglutinins; D001323:Autoantibodies