Immunoglobulin classes of antibody to hepatitis B core antigen.
Antibody to hepatitis B core antigen in the sera of 10 patients with acute viral hepatitis B, 20 patients with chronic hepatitis B, and 30 carriers of chronic hepatitis B surface antigen was assayed by the indirect immunofluorescence test. The activity of antibody to hepatitis B core antigen in the sera of these three groups of patients was identified as belonging to immunoglobulin classes G, M, A, and D. Antibody to hepatitis B core antigen was predominantly of IgG and IgM classes in all three groups of patients.
D000208:Acute Disease; D000328:Adult; D000914:Antibodies, Viral / Q000145:classification*; D002353:Carrier State / Q000276:immunology*; D002908:Chronic Disease; D005260:Female; D005455:Fluorescent Antibody Technique; D006509:Hepatitis B / Q000276:immunology*; D006511:Hepatitis B Antigens; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007072:Immunoglobulin D / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008875:Middle Aged
D000914:Antibodies, Viral; D006511:Hepatitis B Antigens; D007070:Immunoglobulin A; D007072:Immunoglobulin D; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins