title: Biological relevance of alkali-labile sites in double-stranded DNA after gamma-irradiation.
abstract: Alkali-labile sites produced by gamma-irradiation in dry RF-DNA of bacteriophage phi chi 174 were found to be lethal lesions with respect to the plaque-forming ability.
mesh_terms: D000468:Alkalies; D002501:Centrifugation, Zonal; D003037:Cobalt Radioisotopes; D003090:Coliphages; D004267:DNA Viruses; D004270:DNA, Circular / Q000528:radiation effects; D004279:DNA, Viral / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D011830:Radiation Effects
chemical_list: D000468:Alkalies; D003037:Cobalt Radioisotopes; D004270:DNA, Circular; D004279:DNA, Viral