[Cerebromeningeal cryptococcosis. Predisposing role of immunosuppressive therapy in patients with kidney transplants].
Disseminated cryptococcal infection is described in eight patients, seven of them with verified meningeal involvement. Six of the eight patients were recipients of a renal homograft and submitted to the classical immunosuppressive treatment. Consideration is given to predisposing factors and to problems in the clinical, biological and mycological diagnosis. Some comments are presented on the often disappointing results of antifungal therapy of cryptococcal meningitis.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001927:Brain Diseases / Q000209:etiology*; D002555:Cerebrospinal Fluid / Q000382:microbiology; D003453:Cryptococcosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D005260:Female; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation; D008228:Lymphoma, Non-Hodgkin / Q000150:complications; D008297:Male; D008581:Meningitis / Q000209:etiology*; D008875:Middle Aged; D011183:Postoperative Complications; D012507:Sarcoidosis / Q000150:complications; D014184:Transplantation, Homologous
D007166:Immunosuppressive Agents; D000666:Amphotericin B; D005437:Flucytosine
Cryptococcose cérébroméningée. Rôle favorisant de la thérapeutique immunosuppressive chez les transplantés rénaux