[2 cases of partial trisomy 10p due to a paternal translocation t(10p;18)(p13;q23)].
Two brothers trisomic for the distal two thirds of 10p are reported. Trisomy results from the malsegregation of a familial translocation rcp (10;18)(p13;q23) present in the father, a half-brother and the grand-father of the propositi. The phenotype is comparable to that of other 10p trisomic patients reported in the literature.
D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002902:Chromosomes, Human, 16-18; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D008297:Male; D014178:Translocation, Genetic; D014314:Trisomy
Deux cas de trisomie 10p partielle dus à une translocation paternelle t(10;18)(p13;q23