title: Toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in larval and adult forms of Rana catesbeiana.
abstract: Varying doses of TCDD ranging from 25 to 1000 mug/kg were administered to the larval and adult forms of the American bullfrog, Rana catesbeiana. Doses of TCDD as high as 1 mg/kg failed to have any significant effect upon survival or completion of metamorphosis in tadpole and doses of up to 500 mug/kg had no effect on survival of adult frogs. Histopathological examination of various tissues from the metamorphosed tadpoles and adult frogs failed to show any abnormalities.
mesh_terms: D000367:Age Factors; D000818:Animals; D004147:Dioxins / Q000633:toxicity*; D005260:Female; D007814:Larva; D008297:Male; D000072317:Polychlorinated Dibenzodioxins / Q000633:toxicity*; D011892:Rana catesbeiana
chemical_list: D004147:Dioxins; D000072317:Polychlorinated Dibenzodioxins