title: Immune response of sheep to Fasciola hepatica infection.
abstract: The IgG immunoglobulin levels and the immune response to Fasciola hepatica digestive tract antigens were studied in experimentally infected lambs. A synchronic increase and decrease of IgG-1 serum levels and indirect fluorescent antibody titres were observed during the course of the infection. Antibody activities were demonstrated in IgG-1, but not in IgG-2 isolates. The antibody activity was partly sensitive to reduction with mercaptoethanol.
mesh_terms: D000818:Animals; D000917:Antibody Formation; D002852:Chromatography, Ion Exchange; D005210:Fasciola hepatica / Q000276:immunology; D005211:Fascioliasis / Q000276:immunology / Q000469:parasitology / Q000662:veterinary*; D005243:Feces / Q000469:parasitology; D005455:Fluorescent Antibody Technique; D007074:Immunoglobulin G / Q000302:isolation & purification; D012756:Sheep; D012757:Sheep Diseases / Q000276:immunology* / Q000469:parasitology
chemical_list: D007074:Immunoglobulin G