title: Antimalarial compounds. XIII. New derivatives of phenyl chloromethyl sulfone.
abstract: A series of chloromethylsulfonyl derivatives of amines, biguanides and amidineureas (Scheme 1) has been prepared and their antimalarial properties investigated.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000962:Antimalarials / Q000138:chemical synthesis* / Q000627:therapeutic use / Q000633:toxicity; D007279:Injections, Subcutaneous; D007928:Lethal Dose 50; D008288:Malaria / Q000188:drug therapy; D051379:Mice; D010962:Plasmodium berghei; D013450:Sulfones / Q000138:chemical synthesis* / Q000627:therapeutic use / Q000633:toxicity
chemical_list: D000962:Antimalarials; D013450:Sulfones