[Cytotoxic and complement-binding activity of rabbit antisera against the cortex and cerebral white matter of rats and humans].
The cytotoxicity and complement-fixation activity of rabbit antisera against rat and human brain cortex and white matter was tested against mouse and rat thymocytes and bone marrow cells. The cytotoxic test proved to be more sensitive and accurate. The cytotoxins to rodent thymocytes were found in the antisera against human brain cortex only. At the same time cytotoxic antibodies were revealed both in the antisera rat brain cortex and white matter; but the former contained much more cytotoxic antibodies than the letter. After absorption with the same antigen the antisera against rat brain cortex lost their cytotoxic effect, but retained it in case of absorption with the white matter.
D000818:Animals; D000906:Antibodies; D001921:Brain / Q000276:immunology*; D002540:Cerebral Cortex / Q000276:immunology; D003165:Complement System Proteins; D003429:Cross Reactions; D003601:Cytotoxicity Tests, Immunologic; D006801:Humans; D007106:Immune Sera; D051379:Mice; D011817:Rabbits; D051381:Rats; D013601:T-Lymphocytes / Q000276:immunology
D000906:Antibodies; D007106:Immune Sera; D003165:Complement System Proteins
Tsitotoksicheskaia i komplementsviazyvaiushchaia aktivnost' krolich'ikh antisyvorotok protiv kroy i belogo veshchestva golovnogo mozga krysy i cheloveka