[Effect of trasyslol on the permeability of the histo-hematic barrier in ischemic myocardium].
Ligation of the descending branch of the left coronary artery caused an increase in the permeability of the histo-hematic barrier of the myocardium for sulfacyl-sodium in the ischemic area and in the region adjacent to it. Trasylol proved to decrease the permeability of the histo-hematic barrier of the myocardium in the mentioned area, without influencing the intact zone. Fluoresceine test demonstrated the presence of membranotropic effect of trasylol; the preparation had no effect on the osmotic stability of erythrocytes in vitro.
D000818:Animals; D007611:Aprotinin / Q000627:therapeutic use*; D001692:Biological Transport; D001769:Blood; D003327:Coronary Disease / Q000188:drug therapy* / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D011817:Rabbits
D007611:Aprotinin
Vliianie trasilola na pronitsaemost' gisto-gematicheskikh bar'erov ishemizirovannogo miokarda