Prophage induction of Escherichia coli (lambda) by N-nitrosamines.
Carcinogenic N-nitrosamines were tested for their ability to induce lambda in a lysogenic strain of Escherichia coli K-12 (58-161 F+ Dimethylnitrosamine, di-n-propylnitrosamine, methyl-n-propylnitrosamine, and N-nitrosopiperidine were shown to be inducers of prophage.
D003090:Coliphages / Q000254:growth & development*; D004048:Diethylamines / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects*; D008242:Lysogeny; D008937:Mitomycins / Q000494:pharmacology; D009602:Nitrosamines / Q000494:pharmacology*; D009603:Nitroso Compounds / Q000494:pharmacology; D010880:Piperidines; D010948:Viral Plaque Assay; D014779:Virus Replication / Q000187:drug effects*
D004048:Diethylamines; D008937:Mitomycins; D009602:Nitrosamines; D009603:Nitroso Compounds; D010880:Piperidines