[Haemodialysis for renal failure in a case of systemic lupus erythematosus (author's transl)].
Severe acute renal failure developed in a patient with systemic lupus erythematosus which was characterized by typical skin rash, polyserositis, haemolytic anaemia and liver damage. Serological examination revealed anti-DNA antibodies in high concentrations, positive Coombs' test, excessive elevation of serum-IgG with markedly depressed serum complement fractions (C3, C4). Acute lupus nephritis led to prolonged oliguria and anuria requiring regular dialysis over almost five months. Immuno-suppressive treatment with cortisone and azathioprine finally reversed the renal failure: BUN returned to 33 mg/  100 ml, with a plasma creatinine of 1.8 mg per 100 ml.
D058186:Acute Kidney Injury / Q000209:etiology / Q000628:therapy*; D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D001002:Anuria / Q000209:etiology; D001379:Azathioprine / Q000627:therapeutic use; D001806:Blood Urea Nitrogen; D003165:Complement System Proteins / Q000032:analysis; D003298:Coombs Test; D003348:Cortisone / Q000627:therapeutic use; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D006435:Renal Dialysis; D012217:Rheumatoid Factor / Q000032:analysis; D013997:Time Factors
D000974:Antibodies, Antinuclear; D007074:Immunoglobulin G; D003165:Complement System Proteins; D012217:Rheumatoid Factor; D003404:Creatinine; D001379:Azathioprine; D003348:Cortisone
Hämodialyse bei Lupus erythematodes disseminatus.  Reversibles Nierenversagen eines Falles mit monatelanger Oligo-Anurie.