title: Doxycycline in the treatment of upper and lower respiratory tract infections. A field trial.
abstract: As part of the Pan-European multi-centre trial of doxycycline in the treatment of respiratory tract infections during the winter of 1973/1974, a field trial was carried out in Austria. 95 physicians provided 540 case reports for evaluation. Very good or good results were obtained in 93.9% of patients and the rate of improvement as indicated by fall in temperature, reduction in cough, sputum and pain, and easing of inflammatory symptoms was rapid; 77.8% of patients showed complete remission of acute symptoms after 3 days of treatment. Only 5.6% of patients suffered from side-effects which were mostly mild. Comparison with a previous field trial in Austria in 1968/1969 showed that doxycycline has retained its efficacy over the years.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D001317:Austria; D001991:Bronchitis / Q000188:drug therapy; D001996:Bronchopneumonia / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004318:Doxycycline / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010033:Otitis Media / Q000188:drug therapy; D010612:Pharyngitis / Q000188:drug therapy; D011014:Pneumonia / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D012852:Sinusitis / Q000188:drug therapy; D014069:Tonsillitis / Q000188:drug therapy
chemical_list: D004318:Doxycycline