title: Host specificity of DNA in Haemophilus influenzae: the in vivo action of the restriction endonucleases on phage and bacterial DNA.
abstract: In Haemophilus influenzae strains only the type 1 of the restriction endonucleases have an in vivo effect on phage and bacterial transforming DNA. The type 2 of restriction endonucleases which act very efficiently in vitro are completely inactive in vivo. The reasons for this inactivity is unknown.
mesh_terms: D000255:Adenosine Triphosphate; D001435:Bacteriophages; D004262:DNA Restriction Enzymes / Q000378:metabolism* / Q000494:pharmacology; D004269:DNA, Bacterial / Q000378:metabolism*; D004279:DNA, Viral / Q000378:metabolism*; D004720:Endonucleases / Q000378:metabolism*; D006190:Haemophilus / Q000378:metabolism; D006193:Haemophilus influenzae / Q000201:enzymology*; D008242:Lysogeny; D012436:S-Adenosylmethionine; D013010:Sonication; D013045:Species Specificity; D014170:Transformation, Genetic / Q000187:drug effects*
chemical_list: D004269:DNA, Bacterial; D004279:DNA, Viral; D012436:S-Adenosylmethionine; D000255:Adenosine Triphosphate; D004720:Endonucleases; D004262:DNA Restriction Enzymes