Experimentally induced infection of neonatal swine with porcine parvovirus.
One-day-old pigs were exposed to porcine parvovirus (PPV) and killed at postinoculation day (PID) 3 or 7. Signs of illness and lesions were not seen. Hemagglutination-inhibition (HI) antibodies for PPV were present in the serums of pigs killed on PID 7. As detected by viral isolation and immunofluorescence, PPV was mainly located in rapidly proliferating tissues. Heaviest concentration of viral antigen was in the germinal centers of lymph nodes and lightest concentration of antigen was in the central nervous system.
D000281:Administration, Intranasal; D000818:Animals; D000831:Animals, Newborn; D000956:Antigens, Viral; D003106:Colon / Q000276:immunology; D005455:Fluorescent Antibody Technique; D007275:Injections, Intravenous; D007668:Kidney / Q000276:immunology; D008099:Liver / Q000276:immunology; D008168:Lung / Q000276:immunology; D008198:Lymph Nodes / Q000276:immunology; D008297:Male; D010321:Parvoviridae / Q000276:immunology / Q000302:isolation & purification; D013552:Swine; D013553:Swine Diseases / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D013737:Testis / Q000276:immunology; D014420:Turbinates / Q000276:immunology; D014777:Virus Diseases / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*
D000956:Antigens, Viral