title: Experimental coronary artery bypass operation. Myocardial blood flow, ventricular performance and regional myocardial function.
abstract: Myocardial blood flow and ventricular function was studied in seven dogs with chronic myocardial ischemia before and after coronary bypass grafting. Restoring blood flow in an area of 25% of the anterior wall of the left ventricle did not significantly improve overall ventricular function. Assessment of intramyocardial pressure as an index of regional myocardial function revealed a consistent enhancement of myocardial contraction at rest, and under pharmacological stress of the heart.
mesh_terms: D000818:Animals; D002122:Calcium Chloride / Q000494:pharmacology; D002908:Chronic Disease; D001026:Coronary Artery Bypass; D003326:Coronary Circulation; D003327:Coronary Disease / Q000503:physiopathology*; D004285:Dogs; D006352:Heart Ventricles / Q000503:physiopathology*; D007275:Injections, Intravenous; D009200:Myocardial Contraction / Q000187:drug effects
chemical_list: D002122:Calcium Chloride