Ciliary ganglion stimulation. I. Effects on aqueous humor inflow and outflow.
Stimulation of the ciliary ganglion in an enucleated, arterially perfused cat eye preparation produced a sustained increase in aqueous humor formation and an increase in the rate of aqueous humor outflow. The increased aqueous humor formation induced by ciliary ganglion stimulation has been found to be pressure-dependent and therefore suggests that ultrafiltration may be the underlying mechanism of action. No change in capillary permeability of the ciliary body could be demonstrated.
D000109:Acetylcholine / Q000037:antagonists & inhibitors; D000818:Animals; D000867:Anterior Chamber; D001082:Aqueous Humor / Q000502:physiology*; D002199:Capillary Permeability; D002415:Cats; D002924:Ciliary Body / Q000098:blood supply / Q000294:innervation*; D003864:Depression, Chemical; D004558:Electric Stimulation; D005260:Female; D005725:Ganglia, Autonomic / Q000187:drug effects / Q000502:physiology*; D007429:Intraocular Pressure; D008297:Male; D009474:Neurons / Q000502:physiology; D009538:Nicotine / Q000494:pharmacology; D009880:Ophthalmic Artery; D010477:Perfusion; D010830:Physostigmine / Q000494:pharmacology; D011865:Radioisotope Dilution Technique; D012025:Reflex, Pupillary; D012711:Serum Albumin, Radio-Iodinated; D013997:Time Factors
D012711:Serum Albumin, Radio-Iodinated; D009538:Nicotine; D010830:Physostigmine; D000109:Acetylcholine