Antibody-dependent lymphocyte-mediated cytotoxicity. The nature of the effector cell and characterization of its fc receptor.
The effector cell in abtibody-dependent lymphocyte-mediated cytotoxicity (ADLMC) have been studied. The cells do not adhere to glass and bear Fc receptors independent of surface Ig and complement receptors. Whereas monocytes have IgG1 and Ig G3 Fc receptors, these Fc receptor lymphocytes appear to have receptors for aggregates of all four IgG subclasses.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D002449:Cell Aggregation; D002645:Chickens; D003165:Complement System Proteins / Q000032:analysis; D003601:Cytotoxicity Tests, Immunologic; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D007104:Immune Adherence Reaction; D007111:Immunity, Cellular; D007141:Immunoglobulin Fc Fragments / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis; D008214:Lymphocytes / Q000276:immunology*; D011817:Rabbits; D011947:Receptors, Antigen, B-Cell / Q000032:analysis; D013601:T-Lymphocytes / Q000276:immunology
D000906:Antibodies; D007141:Immunoglobulin Fc Fragments; D007136:Immunoglobulins; D011947:Receptors, Antigen, B-Cell; D003165:Complement System Proteins