Antimicrobial agents from higher plants.  The quaternary alkaloids of Ptelea trifoliata.
Quaternary alkaloid extracts of Ptelea trifoliata showed potentially interesting antimicrobial activity.  Chromatographic examination showed the presence of six components.  Of these, choline and O-4-methyl ptelefolinium were known compounds.  Rational structures are proposed for the new alkaloids, O-4-methylhydroxyluninium, neohydroxylunine and pteleatinium salts.  Pteleatinium salt is responsible for the antimicrobial activity of the extracts of the plant.
D000470:Alkaloids / Q000032:analysis*; D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000494:pharmacology; D000935:Antifungal Agents / Q000032:analysis; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D004148:Dioxolanes / Q000032:analysis; D005663:Furans / Q000032:analysis / Q000494:pharmacology; D006912:Hydroxyquinolines / Q000032:analysis*; D009161:Mycobacterium / Q000187:drug effects; D009820:Ohio; D010946:Plants, Medicinal / Q000032:analysis*; D011804:Quinolines / Q000032:analysis* / Q000494:pharmacology; D014197:Trees / Q000032:analysis
D000470:Alkaloids; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D004148:Dioxolanes; D005663:Furans; D006912:Hydroxyquinolines; D011804:Quinolines