title: [Wiscott-Aldrich syndrome. Description of a case].
abstract: The Wiscott-Aldrich syndrome with the classical symptomatology (eczema, thrombocytopenia and susceptibility to infections) has been described in a 3-month-old child. The family history, together with the evidence of an immunological deficiency involving both thymus-dependent lymphocyte and immunoglobulin-antibody systems have given important clues to diagnosis. Impairment of immunoglobulin homoeostasis and its relevance to the assessment of heterozygotes is discussed.
mesh_terms: D000917:Antibody Formation; D001777:Blood Coagulation; D001798:Blood Proteins / Q000032:analysis; D006801:Humans; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007223:Infant; D008213:Lymphocyte Activation; D008297:Male; D010375:Pedigree; D013601:T-Lymphocytes / Q000276:immunology; D014923:Wiskott-Aldrich Syndrome / Q000235:genetics*
chemical_list: D001798:Blood Proteins; D007070:Immunoglobulin A; D007074:Immunoglobulin G
vernacular_title: Sindrome di Wiscott-Aldrich descrizione di un caso