[Induction of autologous tissue disorders in animals tolerant to cross-reacting microbial antigens].
Injection to newborn C3H mice of streptococcus, group C, or C. albicans vaccines prevented in adult mice induction of the skin autotransplant affection caused by the immunization of these animals with the mentioned microbial vaccines. In response to the immunization with the streptococcus or monilia vaccines the tolerant mice displayed a reduction in the number of cells reacting with the microbial vaccines in the immunoadhesion and blasttransformation reactions; their cytotoxic activity in respect to the syngenous target cells was also diminished.
D000818:Animals; D000937:Antigen-Antibody Reactions; D000942:Antigens, Bacterial; D000946:Antigens, Fungal; D002176:Candida albicans / Q000276:immunology*; D003429:Cross Reactions; D003601:Cytotoxicity Tests, Immunologic; D004926:Escherichia coli / Q000276:immunology*; D007108:Immune Tolerance; D008213:Lymphocyte Activation; D051379:Mice; D008809:Mice, Inbred C3H; D016038:Skin Transplantation; D013291:Streptococcus / Q000276:immunology; D014181:Transplantation Immunology; D014182:Transplantation, Autologous
D000942:Antigens, Bacterial; D000946:Antigens, Fungal
Izuchenie induktsii porazheniia autologichnoĭ tkani u zhivotnykh, tolerantnykh k perekrestno reagiruiushchim mikrobnym antigenam