Bronchiectasis and homozygous alpha1-antitrypsin deficiency.
A 34-year-old woman with homozygous a1-antitrypsin deficiency suffered from progressive, generalized cystic bronchiectasis. Although bronchiectasis was reported in the original monograph on the enzyme inhibitor deficiency, it has received minimal attention since then. Alpha1-antitrypsin levels should be measured in patients with severe bronchiectasis.
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001987:Bronchiectasis / Q000201:enzymology* / Q000235:genetics / Q000628:therapy; D001993:Bronchodilator Agents / Q000627:therapeutic use; D005260:Female; D006720:Homozygote; D006801:Humans; D026741:Physical Therapy Modalities; D011175:Positive-Pressure Respiration; D012907:Smoking; D019896:alpha 1-Antitrypsin Deficiency
D000900:Anti-Bacterial Agents; D001993:Bronchodilator Agents