Assessment of Peroheme-40 for the presence of occult blood in the faeces.
Peroheme 40, a chemical test for occult blood in faeces, has been assessed by comparing it with results obtained using 51Cr labelled red cells. The study was carried out in two parts. Initially testing was carried out on 75 stool samples from 20 patients on a restricted diet, and in the second part, testing was performed on 40 samples from 10 patients on a normal ward diet. All patients were suspected of losing blood from the gastrointestinal tract. On the restricted diet there were 29 per cent false positive and 13 per cent false negative results, while on the normal diet, there were 86 per cent false positive and 8 per cent false negative results. Peroheme-40 has therefore been shown, on a restricted diet, to compare favourably with previously available chemical tests.
D015086:2,6-Dichloroindophenol; D002860:Chromium Radioisotopes; D004032:Diet; D005188:False Negative Reactions; D005189:False Positive Reactions; D005243:Feces / Q000032:analysis*; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis; D006801:Humans; D007215:Indophenol / Q000031:analogs & derivatives*; D008551:Melena / Q000175:diagnosis; D009780:Occult Blood
D002860:Chromium Radioisotopes; D007215:Indophenol; D015086:2,6-Dichloroindophenol