Smooth muscle antibody in patients with warts.
Sera from fifty-four patients with warts were tested for the presence of commonly found autoantibodies. Smooth muscle antibody (SMA) was detected at a significantly higher level than in a control group of healthy blood donors matched for age and sex, and was in the IgM class. The SMA-positive sera gave a microfilamentous staining pattern also in the IgM class, on fixed HEp2 tissue culture cells. Absorption of positive sera with smooth muscle removed both SMA staining and the anti-cellular staining.
D000974:Antibodies, Antinuclear / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D007075:Immunoglobulin M / Q000378:metabolism; D008297:Male; D008928:Mitochondria / Q000276:immunology; D009130:Muscle, Smooth / Q000276:immunology*; D012155:Reticulin / Q000276:immunology; D013270:Stomach / Q000276:immunology; D014860:Warts / Q000276:immunology*
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012155:Reticulin