title: beta-blocking drugs and renin secretion in the anaesthetized dog.
abstract: 1. The effect of propranolol and sotalol on renin secretion was studied in the anaesthetized dog. 2. beta-adrenergic blockade did not modify basal renin secretion and did not affect the rise of renin secretion induced by haemorrhage or aortic constriction. 3. beta-adrenergic blockade diminished the rise in renin secretion induced by stimulation of the renal nerves.
mesh_terms: D000818:Animals; D001011:Aorta; D004285:Dogs; D004558:Electric Stimulation; D006470:Hemorrhage / Q000503:physiopathology; D007511:Ischemia; D007668:Kidney / Q000294:innervation; D011433:Propranolol / Q000494:pharmacology*; D012083:Renin / Q000097:blood*; D013015:Sotalol / Q000494:pharmacology*
chemical_list: D011433:Propranolol; D013015:Sotalol; D012083:Renin