Adrenaline and the electrogenic sodium pump in Rana catesbeiana sympathetic ganglion cells.
The effect of adrenaline on the Na+-pump in bullfrog (Rana catesbeiana) sympathetic ganglion cells was studied by use of electrophysiological methods. The rate of removal of excess Na+ injected into a ganglion cell was increased by adrenaline. The K+-activated hyperpolarization of cell membrane, which might be produced by an electrogenic Na+-pump, was also increased by adrenaline. These results suggested that adrenaline was able to accelerate the Na+-pump, possibly the electrogenic Na+-pump.
D000200:Action Potentials; D000818:Animals; D001001:Anura; D001693:Biological Transport, Active / Q000187:drug effects; D004837:Epinephrine / Q000494:pharmacology*; D005725:Ganglia, Autonomic / Q000187:drug effects / Q000378:metabolism*; D008564:Membrane Potentials / Q000187:drug effects; D011188:Potassium / Q000494:pharmacology; D011892:Rana catesbeiana; D012964:Sodium / Q000378:metabolism* / Q000494:pharmacology
D012964:Sodium; D011188:Potassium; D004837:Epinephrine