[Gene localization in the chimpanzee (Pan troglodytes). Comparison with the factor mapping of man (Homo sapiens)].
Ten independant cellular hybrids were obtained from Chimpanzee (Pan troglodytes) fibroblasts and the murine cell line C11D. The comparison of electrophoretic and cytogenetic studies showed that 9 markers with known localizations in Man could also be localized on the homologous chromosomes of the Chimpanzee: pyrophosphate hydratase (PPH), phosphoglucomutase-1 (PGM1), and peptidase-C (Pep-C) on the No. 1; malate dehydrogenase MDH(NAD) on the No. 2; lactico dehydrogenase-A (LDH-A) on the No. 11; lactico dehydrogenase-B (LDH-B) on the No. 12; thymidine kinase (TK) on the No. 17; superoxide dismutase-1 (SOD-1) on the No. 21; glucose-6-phosphate dehydrogenase (G6PD) on the X. The localization of mannose phosphate isomerase (MPI) on the No. 7 could be excluded. One discrepancy between Chimpanzee and Man was noted: the localization of superoxide dismutase-2 (SOD-2) on the 6 is excluded.
D000818:Animals; D002874:Chromosome Mapping; D004586:Electrophoresis; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis; D006801:Humans; D006822:Hybrid Cells / Q000201:enzymology; D007527:Isoenzymes; D007535:Isomerases / Q000032:analysis; D007621:Karyotyping; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008291:Malate Dehydrogenase; D008297:Male; D008358:Mannose; D051379:Mice; D002679:Pan troglodytes / Q000235:genetics*; D010447:Peptide Hydrolases / Q000032:analysis; D010733:Phosphoglucomutase / Q000032:analysis; D013482:Superoxide Dismutase / Q000032:analysis; D013937:Thymidine Kinase / Q000032:analysis
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D008291:Malate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D013482:Superoxide Dismutase; D013937:Thymidine Kinase; D010447:Peptide Hydrolases; D007535:Isomerases; D010733:Phosphoglucomutase; D008358:Mannose
Localisations géniques chez le chimpanzé (Pan troglodytes) Comparaison avec la carte factorielle de l'homme (Homo sapiens)