[Effectiveness of prodigiozan in the therapy of chronic nonspecific diseases of the lungs].
The efficiency of the Soviet prodigiozan in therapy of chronic non-specific diseases of the lungs (18 cases with bronchial asthma and 26 cases with chronic pneumonia of the 1st and 2nd stages) in the phase of exacerbation was studied. The results of the treatment were estimated by the clinico-roentgenological pictures. The effect of prodigiozan on breathing and the functional state of the adrenal gland was studied in particular. Satisfactory results were obtained in the patients suffering from chronic pneumonia of the 1st and 2nd stages without clinical signs of the bronchial tree affection and in the patients with infection-allergic forms of bronchial asthma. Modest results were observed in the patients suffering from chronic pneumonia of the 1st and 2nd stages with the bronchial tree affection, especially when exacerbated by the asthma syndrome. In some patients the results of the treatment with prodigiozan were not stable. Prodigiozan improved the bronchial permeability, stimulated the sympatho-adrenal system and had no effect on the adrenal cortex.
D015062:11-Hydroxycorticosteroids / Q000097:blood; D000304:Adrenal Cortex Function Tests; D001249:Asthma / Q000188:drug therapy; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004837:Epinephrine / Q000652:urine; D005500:Follow-Up Studies; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy; D008171:Lung Diseases / Q000188:drug therapy*; D009638:Norepinephrine / Q000652:urine; D011014:Pneumonia / Q000188:drug therapy; D011353:Prodigiosin / Q000008:administration & dosage / Q000627:therapeutic use*; D012129:Respiratory Function Tests; D013997:Time Factors
D015062:11-Hydroxycorticosteroids; D011353:Prodigiosin; D009638:Norepinephrine; D004837:Epinephrine
Effectivnost' prodigiozana v terapii bol'nykh s khronicheskimi nespetsificheskimi zabolevaniiami legkikh