title: The management of rhinoscleroma.
abstract: This investigation showed that the organism klebsiella rhinoscleromatis was present consistently in our cases. It was found to be difficult to eradicate completely although seemingly sensitive to common antibiotics in vitro. A prolonged treatment with bactericidal antibiotics is therefore necessary to eradicate it. Nasal dilatation rather than excision of granulations is required to restore nearly-normal physiological nasal function. Excision or cautery of granulations inside the nose is discouraged so as to avoid atropic changes.
mesh_terms: D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002701:Chloramphenicol / Q000627:therapeutic use; D004106:Dilatation; D006801:Humans; D007711:Klebsiella pneumoniae / Q000302:isolation & purification; D008297:Male; D008826:Microbial Sensitivity Tests; D012226:Rhinoscleroma / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery; D013307:Streptomycin / Q000627:therapeutic use; D013752:Tetracycline / Q000627:therapeutic use; D014454:Uganda
chemical_list: D000900:Anti-Bacterial Agents; D002701:Chloramphenicol; D000667:Ampicillin; D013752:Tetracycline; D013307:Streptomycin