High dose ascorbic acid in the management of thalassaemia leg ulcers--a pilot study.
Eight patients with beta thalassaemia major suffering from leg ulcers, were treated over an 8-week period with 3 g ascorbic acid daily in a controlled double-blind crossover study. The ulcers of all the patients showed a high rate of either complete or partial healing.
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D001205:Ascorbic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000150:complications / Q000188:drug therapy*; D008297:Male; D010865:Pilot Projects; D010919:Placebos; D013789:Thalassemia / Q000150:complications*
D010919:Placebos; D001205:Ascorbic Acid