C3 receptor. A marker of a thymus-dependent B-cell subpopulation.
Depletion of C3-binding cells from spleen virtually abolishes the T cell-dependent response to sheep erythrocytes as assessed by transfer experiments. It is suggested that a functionally thymus-dependent B-cell subpopulation (B2) can be distinguished by surface receptors for C3.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D001666:Binding Sites, Antibody; D002462:Cell Membrane / Q000276:immunology; D003176:Complement C3; D003165:Complement System Proteins; D007104:Immune Adherence Reaction; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008264:Macrophages / Q000276:immunology; D051379:Mice; D013154:Spleen; D013601:T-Lymphocytes
D003176:Complement C3; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D003165:Complement System Proteins