title: Transport in bacteriophage P22-infected Salmonella typhimurium.
abstract: There was rapid efflux of L-leucine, L-phenylalanine, and alpha-methyl-D-glucoside after infection of Salmonella typhimurium with the clear plaque mutant C1 of phage P22. The efflux was similar to that observed with cyanide or arsenate treatment except that there was partial recovery in the case of phage infection and almost complete recovery under the condition of lysogeny. There was no efflux after infection with the temperature-sensitive mutant ts16C1 at nonpermissive temperature. Superinfection of superinfection exclusion negative lysogen (sie A minus sie B minus) with C1 led to efflux, whereas the efflux was much less on superinfection of sie A+ Sie B+ lysogen. These results indicate that an effective injection process is enough to cause depression in the cellular transport processes.
mesh_terms: D001149:Arsenates / Q000494:pharmacology; D001693:Biological Transport, Active / Q000187:drug effects; D002250:Carbon Radioisotopes; D002462:Cell Membrane / Q000378:metabolism; D003486:Cyanides / Q000494:pharmacology; D007700:Kinetics; D007930:Leucine / Q000378:metabolism*; D008242:Lysogeny; D008759:Methylglycosides / Q000378:metabolism*; D009154:Mutation; D010649:Phenylalanine / Q000378:metabolism*; D012483:Salmonella Phages / Q000254:growth & development*; D012486:Salmonella typhimurium / Q000378:metabolism*; D013237:Stereoisomerism; D013696:Temperature; D014762:Viral Interference; D014779:Virus Replication
chemical_list: D001149:Arsenates; D002250:Carbon Radioisotopes; D003486:Cyanides; D008759:Methylglycosides; D010649:Phenylalanine; D007930:Leucine