Determination of the von Willebrand's disease antigen (factor VIII-related antigen) in plasma by quantitative immunoelectrophoresis.
Measurement of the von Willebrand's disease antigen (factor viii-related antigen) has become an increasingly useful tool in the differential diagnosis of those disorders of hemostasis characterized by an abnormality of factor viii procoagulant activity.  Optimal conditions for assay of the von Willebrand's disease antigen in plasma by the quantitive immunoelectrophoretic technique are described.  Potential sources ofsystematic error have been evaluated and a dilution effect has been identified.
D000818:Animals; D000941:Antigens / Q000032:analysis*; D002845:Chromatography; D003937:Diagnosis, Differential; D005169:Factor VIII / Q000276:immunology*; D006801:Humans; D007122:Immunoelectrophoresis / Q000379:methods; D011817:Rabbits; D012712:Serum Globulins / Q000032:analysis*; D014842:von Willebrand Diseases / Q000276:immunology*
D000941:Antigens; D012712:Serum Globulins; D005169:Factor VIII