Antidermatophytic activity of 2-thiotetrahydro-1,3,5-thiadiazines and isothiocyanates.
Benzyl, furfuryl, tetrahydronaphthyl, alpha-picolyl, and alpha-homopicolyl derivatives of 2-thiotetrahydro-1,3,5-thiadiazines were studied and found to be more active than beta-picolyl, and pyridyl analogs on dermatophytes, including the more resistant Microsporum canis.
D000935:Antifungal Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D004821:Epidermophyton / Q000187:drug effects; D006118:Griseofulvin / Q000494:pharmacology; D008864:Microsporum / Q000187:drug effects; D013829:Thiadiazines / Q000494:pharmacology*; D013843:Thiazines / Q000494:pharmacology*; D013861:Thiocyanates / Q000494:pharmacology*; D014249:Trichophyton / Q000187:drug effects
D000935:Antifungal Agents; D013829:Thiadiazines; D013843:Thiazines; D013861:Thiocyanates; D006118:Griseofulvin