[Effect of insulin and adrenaline on the respiration and glycolysis of the skeletal muscle of frog].
It was shown in the experiments on isolated sartorius muscles of the frog that insulin increased endogenous respiration by 10 mm3 O2 hr per gramm of wet weight. The effect of insulin and epinephrine on respiration is additive. Insulin in middle (5--50 milliunits/ml) and low, physiological, (50 microunits/ml) concentration does not induce acceleration of glycolyses. The conclusion was confirmed that the increase of the endogenous respiration by insulin cannot be accounted for by the mobilization of the substrate of glycolysis. In the presence of epinephrine, the low concentration (50 microunits/ml) of insulin induces the decrease of the content of glucose-6-phosphate. It is probably connected with the influence of insulin on the concentration level of the cAMP.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001001:Anura; D003470:Culture Media; D046508:Culture Techniques; D004357:Drug Synergism; D004837:Epinephrine / Q000494:pharmacology*; D005958:Glucosephosphates / Q000378:metabolism; D006019:Glycolysis / Q000187:drug effects*; D007328:Insulin / Q000494:pharmacology*; D007773:Lactates / Q000378:metabolism; D009132:Muscles / Q000378:metabolism*; D010101:Oxygen Consumption / Q000187:drug effects*; D011896:Rana temporaria
D003470:Culture Media; D005958:Glucosephosphates; D007328:Insulin; D007773:Lactates; D000255:Adenosine Triphosphate; D004837:Epinephrine
Vliianie insulina i adrenalina na dykhanie i glikoliz skeletnykh myshts liagushki.