[Effect of ATP on the sensitivity of the from heart to adrenaline].
Adenosinthreephosphoric acid (ATP) in concentration 1-10(-6)--1-10(-5) g/ml decreases sensitivity of the frog heart muscle to adrenaline by half. It is suggested that ATP present in the specific granules of adrenals, c. n. s. and adrenergic axons together with catecholamines and excreted with the mediator during excitation of adrenergic nerve, alters the sensitivity of postsynaptic membrane to adrenaline.
D000255:Adenosine Triphosphate / Q000494:pharmacology*; D000818:Animals; D001001:Anura; D004837:Epinephrine / Q000037:antagonists & inhibitors*; D006321:Heart / Q000187:drug effects*; D011896:Rana temporaria; D011941:Receptors, Adrenergic / Q000187:drug effects
D011941:Receptors, Adrenergic; D000255:Adenosine Triphosphate; D004837:Epinephrine
Vliianie ATP na chuvstvitel'nost' serdtsa liagushki k adrenalinu