Rejoining of radiation-induced single-strand breaks in deoxyribonucleic acid of Escherichia coli: effect of phenethyl alcohol.
Single-strand breaks in deoxyribonucleic acid of Escherichia coli B/r cells exposed to 20 krads of gamma radiation could be rejoined by incubation of irradiated cells in growth medium. In the presence of 0.25% phenethyl alcohol, this repair was completely inhibited although deoxyribonucleic acid and protein syntheses were suppressed only partially.
D000438:Alcohols / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000096:biosynthesis; D001555:Benzene Derivatives; D002250:Carbon Radioisotopes; D002499:Centrifugation, Density Gradient; D004260:DNA Repair / Q000187:drug effects*; D004269:DNA, Bacterial / Q000096:biosynthesis / Q000528:radiation effects*; D004926:Escherichia coli / Q000378:metabolism*; D005720:Gamma Rays; D007930:Leucine / Q000378:metabolism; D011827:Radiation; D011830:Radiation Effects; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D000438:Alcohols; D001426:Bacterial Proteins; D001555:Benzene Derivatives; D002250:Carbon Radioisotopes; D004269:DNA, Bacterial; D014316:Tritium; D007930:Leucine; D013936:Thymidine