title: Potential for in vivo acquisition of R plasmids by one strain of Vibrio cholerae biotype El tor.
abstract: The feces of five patients admitted to a hospital during an outbreak of cholera in Melbourne, Australia, in November 1972, were examined for the presence of tetracycline-resistant coliforms and tetracycline-resistant strains of Vibrio cholerae. Despite the abundance of tetracycline-resistant coliforms able to transfer this resistance to other strains of Escherichia coli, no tetracycline-resistant strains of V. cholerae were detected. In vitro transfer experiments using the V. cholerae strain responsible for the outbreak as recipient revealed that it was a particularly poor host for most R plasmids.
mesh_terms: D002771:Cholera / Q000382:microbiology; D003227:Conjugation, Genetic; D004352:Drug Resistance, Microbial; D004926:Escherichia coli; D005111:Extrachromosomal Inheritance; D005243:Feces / Q000382:microbiology; D005787:Gene Frequency; D006801:Humans; D008826:Microbial Sensitivity Tests; D010957:Plasmids; D011815:R Factors; D013752:Tetracycline / Q000494:pharmacology; D014734:Vibrio cholerae / Q000187:drug effects / Q000502:physiology*
chemical_list: D013752:Tetracycline