Antibiotic A-16316-C, a new water-soluble basic antibiotic.
A new water-soluble basic antibiotic named antibiotic A-16316-C was isolated together with antibiotic A-396-I and hygromycin B from a streptomyces strain identified as Streptoverticullium eurocidicus.  The properties of the antibiotic A-16316-C were similar to those of destomycin B.  But it was found that the antibiotic A-16316-C was not identical with destomycin B on the basis of NMR analysis.  On acidic degradation antibiotic A-16136-C gave N, N'-dimethyl-2-deoxystreptamine, destomic acid and D-mannose.  The gross structure for antibiotic A-16136-C was deduced from chemical reactions and spectral data.
D000617:Aminoglycosides / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D002852:Chromatography, Ion Exchange; D002855:Chromatography, Thin Layer; D004926:Escherichia coli / Q000187:drug effects; D005285:Fermentation; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D009161:Mycobacterium / Q000187:drug effects; D013055:Spectrophotometry, Infrared; D013210:Staphylococcus / Q000187:drug effects; D013302:Streptomyces / Q000378:metabolism
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents