[Activity inhibiting leukocyte migration in human sera of healthy subjects and of subjects with delayed hypersensitivity and findings of possible serum factors with antagonistic activity (author's transl)].
The AA. have tested human sera from subjects with a clinical condition of delayed hypersensitivity (TBC and eczematous contact dermatitis) in order to detect factors affecting leukocyte migration in agarose plates. They found either inhibiting or stimulating factors of cellular migration. According to the most recent data about the same area they emphasyze a sort a regulatory mechanism of LIF or factors with activity LIF-like, due to antagonistic substances present in sera of their patients. Furthermore they suggest a list of factors able to inhibit or to enhance cellular migration.
D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology; D002464:Cell Migration Inhibition; D003877:Dermatitis, Contact / Q000276:immunology; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D007962:Leukocytes / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology; D014391:Tuberculosis, Miliary / Q000276:immunology
Attivita'inibente la migrazione leucocitaria nel siero di donatori sani e di soggetti con ipersensibilita' ritardata e riscontro di possibili fattori sierici ad attivita' antagonista