title: [Lytic antibodies in antibacterial sera. IV. Lytic activity of H-antibodies].
abstract: The authors studied the lytic and agglutinating activity of H-antibodies against S. typhimurium. Sera containing H-antibodies proved to possess a distinct lytic activity expressed in the presence of a complement and caused by specific antibodies. In H-antibodies specific lytic activity (as per 1 agglutinating unit) was much weaker than in O-antibodies. A relatively low lytic action of H-antibodies was apparently associated with topography of corresponding antigenic determinants of the microbial cell which determined the low possibility of fatal injuries. In examination of H-bacteriolysins there was revealed the same regularity as noted in studying the O-bacteriolysins: reduction of the lytic activity of antibodies in hyperimmunization.
mesh_terms: D000907:Antibodies, Bacterial; D001433:Bacteriolysis; D005407:Flagella / Q000276:immunology*; D007106:Immune Sera; D012486:Salmonella typhimurium / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D007106:Immune Sera
vernacular_title: Liticheskie antitela v antibakterial'nykh syvorotkakh. Soobshchenie IV. Liticheskaia aktivnost' H-antitel