title: Changes in the lymphocyte cytoplasmic refractive index following typhoid vaccination.
abstract: The refractive index of the circulating blood lymphocytes (LCRI) of healthy young adults vaccinated with typhoid vaccine has been measured by immersion refractometry and phase contrast microscopy. A rise in the LCRI preceeds the rise in the antibody titre by two to three days. A more pronounced rise also occurred in one patient prior to a rejection crises following a kidney transplant.
mesh_terms: D000293:Adolescent; D000371:Agglutination; D000818:Animals; D000906:Antibodies / Q000032:analysis; D002417:Cattle; D003593:Cytoplasm / Q000276:immunology*; D005260:Female; D006084:Graft Rejection; D006801:Humans; D016030:Kidney Transplantation; D008214:Lymphocytes / Q000276:immunology* / Q000648:ultrastructure; D008297:Male; D008858:Microscopy, Phase-Contrast; D011506:Proteins; D051381:Rats; D012710:Serum Albumin, Bovine; D013997:Time Factors; D014184:Transplantation, Homologous; D014435:Typhoid Fever / Q000276:immunology*; D014436:Typhoid-Paratyphoid Vaccines / Q000494:pharmacology; D014611:Vaccination
chemical_list: D000906:Antibodies; D011506:Proteins; D014436:Typhoid-Paratyphoid Vaccines; D012710:Serum Albumin, Bovine