title: Dimethyl sulfoxide therapy in nonmongoloid infantile oligophrenia.
abstract: We are herein submitting the results obtained with a group of 13 nonmongoloid, oligophrenic children after 180 days' treatment with DAT, and we have compared the results with those of a control group that received only conventional treatment. The children were examined before and after the treatment by means of the Binet-Simon tests, which have been standardized by Kuhlmann, and the Wise and Terman Merrill test. The control of organic lesion was determined by the Bender test. The variation mean of the control group was 0.08, and that of the DAT-treated group was 0.954; 0.874 was the mean difference, and 0.543 and 1.205 were the degrees of reliability. The difference between the results obtained from the DAT-treated group and the one that received conventional medication was significant (P equal 0.01). None of the 13 cases treated showed any signs of toxicity.
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004121:Dimethyl Sulfoxide / Q000627:therapeutic use*; D005260:Female; D006225:Hand / Q000503:physiopathology; D006801:Humans; D008607:Intellectual Disability / Q000145:classification / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D007804:Language Development / Q000187:drug effects; D008297:Male; D009048:Motor Skills / Q000187:drug effects; D011187:Posture; D011594:Psychometrics; D013998:Time Perception / Q000187:drug effects; D014796:Visual Perception / Q000187:drug effects
chemical_list: D004121:Dimethyl Sulfoxide