Orthodontics and dentistry for the hemophilic patient.
In this presentation we have contrasted the normal blood-clotting mechanism with the failure to form blood clots in hemophiliacs due to the absence of protein factors necessary for conversion of prothrombin to thrombin. The statistics, hereditary basis, and long-term disabling consequences of hemophilia to the severely ffected patient are described. The systemic means of minimizing severe joint disabilities and serious internal bleeding hazards by employing concentrates of antihemophilic factors to reverse the bleeding defects are discussed. Availability and advantages of the types of concentrates are explained. The fatalistic attitude of hemophiliacs toward hepatitis is discussed, along with admonitions to avoid the use of aspirin, alcohol, and buttock injections. Alternative medications for pain are recommended; and injection sites for pediatric patients are suggested. The details of simplified oral surgical management of hemophilic patients without hospitalization are described, including local anesthetic injection technique, method of performing extractions, general anesthesia techniques when indicated, materials for packing of extraction sockets, regimen and precautions in use of Amicar administration for clot maintenance, postoperative diet, and postsurgical activity guidelines. Also noted is the self-administration of intravenous concentrate infusions at home in the event of hemorrhagin, so that bleeding is on the way to bein controlled even before the patient reaches the hospital. We avoided orthodontic treatment of hemophilic patients in the past; however, recently developed bracket-fixation techniques and auxiliary aids; along with an enlightened understanding that gingival bleeding is ot to be feared, have changed our attitude, and we now treat hemophilic patients in much the same manner as otherwise normal orthodontic patients...
D000766:Anesthesia, Dental; D001241:Aspirin / Q000009:adverse effects; D001792:Blood Platelets / Q000187:drug effects; D002081:Buttocks; D005169:Factor VIII / Q000627:therapeutic use; D005884:Gingival Hemorrhage / Q000209:etiology; D006467:Hemophilia A / Q000235:genetics; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D006992:Hypnosis, Dental; D007267:Injections / Q000009:adverse effects; D007592:Joint Diseases / Q000209:etiology; D008487:Medical History Taking; D009910:Oral Hygiene; D009967:Orthodontic Appliances / Q000009:adverse effects; D009971:Orthodontics, Corrective; D014076:Tooth Diseases / Q000628:therapy*; D014081:Tooth Extraction / Q000379:methods; D014099:Toothbrushing
D005169:Factor VIII; D001241:Aspirin