[T- and B-lymphocytes in the so-called collagenoses].
Lymphocytes of peripheral blood of patients with systemic lupus erythematosus, scleroderma and dermatomyositis were investigated, and relatively, with regard to T- or B-cell characteristics. T-lymphocytes of most patients with SLE were decreased both absolutely. B-lymphocytes mostly showed only a relative increase. Successful immunosuppressive treatment usually accompanied by normalization of T-cell number and with decrease of B-cells. This differentiation of lymphocytes is an additional aid in the determination of activity of SLE and a useful index of immunosuppressive-cytostatic treatment.
D000974:Antibodies, Antinuclear / Q000032:analysis; D001402:B-Lymphocytes / Q000276:immunology*; D003095:Collagen Diseases / Q000276:immunology*; D003165:Complement System Proteins / Q000032:analysis; D004247:DNA / Q000276:immunology; D003882:Dermatomyositis / Q000276:immunology; D006801:Humans; D007104:Immune Adherence Reaction; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007958:Leukocyte Count; D008179:Lupus Erythematosus, Discoid / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy / Q000276:immunology; D011947:Receptors, Antigen, B-Cell / Q000032:analysis; D012594:Scleroderma, Localized / Q000276:immunology; D012595:Scleroderma, Systemic / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
D000974:Antibodies, Antinuclear; D007166:Immunosuppressive Agents; D011947:Receptors, Antigen, B-Cell; D003165:Complement System Proteins; D004247:DNA
T- und B-Lymphocyten bei sogenannten Kollagenosen