[Degradation of yeast mitochondria induced by anaerobiosis at the early stages of growth of the culture].
Prolonged anaerobiosis of Saccharomyces cerevisiae cells result in degenerative changes in mitochondria which can be revealed when measuring the enzyme activities of the respiratory chain in isolated organellas and by electron microscope examination of the cells. The sensitivity of yeast mitochondria to anaerosiosis alters as the culture growth. Mitochondria are especially labile during the early expotential growth phase. Possible reasons for and mechanism of degradation of mitochondria in vivo are discussed.
D000332:Aerobiosis; D000693:Anaerobiosis; D002455:Cell Division; D002458:Cell Fractionation; D002701:Chloramphenicol / Q000494:pharmacology; D003470:Culture Media; D003513:Cycloheximide / Q000494:pharmacology; D008854:Microscopy, Electron; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism; D010101:Oxygen Consumption; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000254:growth & development / Q000648:ultrastructure; D013997:Time Factors; D015003:Yeasts / Q000648:ultrastructure
D003470:Culture Media; D002701:Chloramphenicol; D003513:Cycloheximide; D009247:NADH, NADPH Oxidoreductases
Degradatsiia mitokhondriĭ drozhzheĭ, indutsirovannaia anaérobiozom na rannikh stadiiakh rosta kul'tury