A preliminary report on cephradine.
Plasma cephradine levels were measured after parenteral and oral administration to healthy adults. Plasma cephradine contrations of 7 - 15 mug/ml were measured after 0.5 g had been administered by mouth, and concentrations of 12 - 57 mug/ml were measured after parenteral administration; they fell to 3 mug/ml within 240 minutes except after intramuscular administration. The results of an open clinical trial conducted among 10 patients suffering from urinary tract infections were satisfactory.
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D002177:Candidiasis / Q000209:etiology; D002511:Cephalosporins / Q000097:blood*; D002515:Cephradine / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use; D004927:Escherichia coli Infections / Q000188:drug therapy; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D008297:Male; D011512:Proteus Infections / Q000188:drug therapy; D011552:Pseudomonas Infections / Q000209:etiology; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000209:etiology
D002511:Cephalosporins; D002515:Cephradine