[Corticosteroid cataracts following kidney transplantation. Investigations on the influence of additional factors upon the development of opacities (author's transl)].
15 patients with kidney transplants were followed up for a period of 3 to 45 months. All but one developed lenticular opacities in the posterior subsapsular region. The opacities were classified according to their severity. It could be shown that the cataract index was correlated to the total amount of corticosteroids given. There is probably an additional effect of age and azathioprin therapy. Possibly, the time of treatment with intermittent hemodialysis also influences cataract development.
D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000328:Adult; D000367:Age Factors; D001379:Azathioprine / Q000009:adverse effects / Q000627:therapeutic use; D002386:Cataract / Q000139:chemically induced* / Q000209:etiology / Q000473:pathology; D005260:Female; D006084:Graft Rejection; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D006435:Renal Dialysis / Q000009:adverse effects; D012306:Risk; D013997:Time Factors; D014184:Transplantation, Homologous
D000305:Adrenal Cortex Hormones; D001379:Azathioprine
Kortikosteroidkatarakte nach Nierentransplantation. Untersuchungen über den Einfluss von Zusatzfaktoren auf die Trübungsentwicklung