Incidence of stress ulcer formation associated with steroid therapy in various shock states.
The use of pharmacologic doses of steroids early in the shock state, within the first hour when possible, for periods of less than forty-eight hours seems to reduce the incidence of gastric ulceration and hemorrhage in low flow states associated with septic, cardiogenic, and hemorrhagic shock.
D000328:Adult; D000368:Aged; D003907:Dexamethasone / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D006854:Hydrocortisone / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008775:Methylprednisolone / Q000009:adverse effects / Q000031:analogs & derivatives / Q000627:therapeutic use; D008875:Middle Aged; D012769:Shock / Q000150:complications / Q000188:drug therapy*; D013256:Steroids / Q000009:adverse effects* / Q000627:therapeutic use; D013276:Stomach Ulcer / Q000209:etiology*; D013312:Stress, Physiological / Q000150:complications*
D013256:Steroids; D003907:Dexamethasone; D006854:Hydrocortisone; D008775:Methylprednisolone