Further studies on the nature of the immunoreactive luteinizing hormone-releasing hormone (LH-RH)-like peptide in human urine.
The chemical nature of the immunoreactive LH-RH-like peptide found in human urine has been investigated using ion-exchange chromatography on carboxymethyl (CM)-cellulose and a radioimmunoassay for LH-RH. A single immunoreactive substance was found in urine after LH-RH administration and in urine samples from untreated subjects. This substance did not have the mobility of either the synthetic decapeptide nor the 3-10 octapeptide on CM-cellulose and the evidence suggests that it may be the 2-10 nonapeptide of LH-RH.
D000328:Adult; D002266:Carboxymethylcellulose Sodium; D002852:Chromatography, Ion Exchange; D003429:Cross Reactions; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000276:immunology / Q000378:metabolism / Q000652:urine*; D006801:Humans; D008297:Male; D010455:Peptides / Q000276:immunology / Q000378:metabolism / Q000652:urine*; D011863:Radioimmunoassay
D010455:Peptides; D007987:Gonadotropin-Releasing Hormone; D002266:Carboxymethylcellulose Sodium