title: Osseous autografts. II. Histological responses to osseous coagulum-bone blend grafts.
abstract: Three human intraosseous lesions were treated using osseous coagulum-bone blend as graft material. These sites were surgically removed 6 to 13 weeks after treatment and the blocks prepared for histologic analysis. Periodontal remodeling at the site of grafting was noted in all specimens. This remodeling involved the osseous walls, periodontal ligament, cementum and graft spicules. Both osteoclastic and osteoblastic activities were seen at the borders of the spicules. Exfoliation of spicules was particularly frequent in the six-week specimen. Nevertheless, regenerating of both bone and cementum was actively taking place even in this early specimen and was still evident in the older specimens. Of particular interest was the apparent marked increase in cementogenesis at the graft sites and the variations in parallel or functional orientation of the periodontal ligament in these areas. Significant functional orientation of segments of the periodontal ligament were seenin the early specimens, but not in the latter one. The reason for such variations in ligament pattern is not known at this time.
mesh_terms: D000328:Adult; D000539:Alveolar Process / Q000033:anatomy & histology* / Q000601:surgery; D016025:Bone Transplantation; D003739:Dental Cementum / Q000033:anatomy & histology; D004912:Erythrocytes; D005888:Gingival Pocket / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010513:Periodontal Ligament / Q000033:anatomy & histology; D010518:Periodontitis / Q000601:surgery*; D014092:Tooth Root / Q000033:anatomy & histology; D014182:Transplantation, Autologous