Management of gallstones in the aged.
Calculous gallbladder disease is the most common indication for intra-abdominal surgery in the elderly.  Feeding bile salts may possibly increase the solubility of cholesterol in bile and may cause diminution in the size of radiolucent gallstones, the principal ingredient of which is cholesterol.  However, indications for such treatment are still not clear, and long-term effectiveness and safety still have to be evaluated.  If the aged patient with gallstones has severe symptoms, is a good medical risk and is not demented, surgical treatment should not be denied because of advanced age.  If the patient has "silent" or "dyspeptic" gallstones and is a poor risk or demented, surgical therapy should be postponed at least temporarily, in the hope that medical methods for dissolving gallstones soon will be perfected.
D000328:Adult; D000368:Aged; D001646:Bile / Q000032:analysis; D001647:Bile Acids and Salts; D001659:Biliary Tract / Q000503:physiopathology; D002769:Cholelithiasis / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D002784:Cholesterol / Q000032:analysis; D002793:Cholic Acids; D005260:Female; D006801:Humans; D008017:Life Expectancy; D008297:Male; D008823:Micelles; D008875:Middle Aged; D010743:Phospholipids / Q000032:analysis; D011183:Postoperative Complications; D011792:Quebec; D012995:Solubility; D013514:Surgical Procedures, Operative / Q000009:adverse effects; D013997:Time Factors
D001647:Bile Acids and Salts; D002793:Cholic Acids; D008823:Micelles; D010743:Phospholipids; D002784:Cholesterol