title: Hemoglobinopathy with prolonged bactermia. A report of two cases.
abstract: Prolonged Escherichia coli bacteremia occurred as a complication of pyelonephritis in two patients with abnormal hemoglobins (SC and SS), despite "appropriate" antibiotic therapy. Careful investigation in each case failed to account for the persistent sepsis. Pyogenic arthritis ultimately developed in both patients.
mesh_terms: D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use; D000755:Anemia, Sickle Cell / Q000150:complications*; D002512:Cephalothin / Q000627:therapeutic use; D004926:Escherichia coli / Q000302:isolation & purification; D004927:Escherichia coli Infections; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D006445:Hemoglobin C Disease / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D009582:Nitrofurantoin / Q000627:therapeutic use; D011704:Pyelonephritis / Q000150:complications; D011776:Pyuria / Q000188:drug therapy; D018805:Sepsis / Q000150:complications* / Q000188:drug therapy / Q000209:etiology; D013997:Time Factors
chemical_list: D005839:Gentamicins; D000667:Ampicillin; D009582:Nitrofurantoin; D002512:Cephalothin