[Diagnostic tests for hypersensitivity to halogen compounds].
The authors present a critical analysis of immunological tests used by some authors to establish the diagnosis of halothane-induced hepatitis. These tests include the lymphocyte transformation test (LTT), the leukocyte migration inhibition test (LMIT) and detection of auto-antibodies. It has not been possible for all investigators to reproduce the results of these tests. The inhibition of these tests is not specific for halothane since it is also observed after infectious and serum viral hepatitis.
D001323:Autoantibodies / Q000032:analysis; D002464:Cell Migration Inhibition; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis* / Q000209:etiology; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology; D006221:Halothane / Q000009:adverse effects*; D007962:Leukocytes / Q000276:immunology; D008213:Lymphocyte Activation; D012882:Skin Tests
D001323:Autoantibodies; D006221:Halothane
Tests diagnostiques d'hypersensibilité aux agents halogenes