[The influence of antimetabolites on Trichomonas vaginalis as an experimental model].
The present study was concerned with the relationship between antimetabolites and Trichomonas vaginalis. In all of the strains (with p-nitrobenzylether of N-acetyldiiodtryrosine) tested, the growth of Trichomonas vaginalis was identical to that of the control series at concentrations up to 2 mg/ml. At higher concentrations a decrease in multiplication was noted. In the experimental series with antitrypsin, from 1 mg/ml produced an inhibiting effect upon the Trichomonas population. Further investigations on the combined inhibition test are envisaged.
D004305:Dose-Response Relationship, Drug; D007470:Monoiodotyrosine / Q000031:analogs & derivatives* / Q000494:pharmacology; D009578:Nitrobenzenes / Q000494:pharmacology; D014246:Trichomonas vaginalis / Q000187:drug effects* / Q000254:growth & development; D014361:Trypsin Inhibitors / Q000494:pharmacology*
D009578:Nitrobenzenes; D014361:Trypsin Inhibitors; D007470:Monoiodotyrosine