title: A selective coronary indicator dilution technique with fiberoptic recording.
abstract: A new method of accurately measuring myocardial circulation times is described: dye injections were made selectively into the left coronary artery while the passage of dye was recorded instantaneously in the coronary sinus with a fiberoptic catheter. The appearance time was found to be shorter than previously estimated (2.2 +/- 0.8 sec). The mean transit time in patients with left coronary artery disease and/or myocardial disease was significantly prolonged (p less than 0.01) and was found in all patients to shorten with increasing heart rate (p less than 0.01). Deformed dyd dilution curves were only obtained with stenotic lesions of the left coronary artery.
mesh_terms: D001158:Arteries; D003326:Coronary Circulation; D003327:Coronary Disease / Q000175:diagnosis*; D003331:Coronary Vessels; D005336:Fiber Optic Technology; D006801:Humans; D007201:Indicator Dilution Techniques; D008722:Methods; D013997:Time Factors; D014680:Veins