title: [Current aspects of differentiation and treatment of pneumocystis carinii pneumonia (author's transl)].
abstract: There are two types of Pneumocystis carinii pneumonia. One is seen in premature and atrophic infants mainly during the 2nd to 6th month, with massive interstitial proliferation of plasmacells and acute respiratory crisis. The second typ is observed in immunodeficient children and adults with only little or no plasmacell infiltration due to the hypoimmune, hypoergic state. Pentamidine is the drug of choice in the therapy of Pneumocystis carinii pneumonia; in serious cases it will be combined with Pyrimethamine. The cocktail Hydergine + Promethazine proved good as a symptomical drug. There have been reports about recoveries in adults under the treatment with Pyrimethamamine + Sulfamethazole. This combination has been recommended as prophylaxis as well.
mesh_terms: D000367:Age Factors; D004088:Dihydroergotoxine / Q000627:therapeutic use; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications; D007223:Infant; D010419:Pentamidine / Q000627:therapeutic use; D011020:Pneumonia, Pneumocystis / Q000145:classification / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D011398:Promethazine / Q000627:therapeutic use; D011739:Pyrimethamine / Q000627:therapeutic use; D013420:Sulfamethoxazole / Q000627:therapeutic use
chemical_list: D004088:Dihydroergotoxine; D010419:Pentamidine; D011398:Promethazine; D013420:Sulfamethoxazole; D011739:Pyrimethamine
vernacular_title: Derzeitige Auffassung über die Entstehungsbedingungen und besten Gehandlungsmöglichkeiten der interstitiellen plasmacellulären Pneumonie