Sinus histiocytosis with massive lymphadenopathy and spinal epidural involvement: a case report and review of the literature.
A case of "sinus histiocytosis with massive lymphoadenopathy" (SHML) in which spinal epidural involvement caused paraplegia is described. The literature pertaining to this newly recognized entity is reviewed; this review indicates that the process is not necessarily restricted to the lymph nodes and may be progressive in nature. The case we report is the first with histologically proved bone involvement.
D003937:Diagnosis, Differential; D006644:Histiocytes / Q000473:pathology; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008206:Lymphatic Diseases / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009333:Neck; D010264:Paraplegia / Q000209:etiology; D013120:Spinal Cord Neoplasms / Q000150:complications / Q000473:pathology*