[A pharmacologic analysis of the slow potential arising in response to adequate stimulation of the frog olfactory bulb].
The nature of slow potential recorded in the frog olfactory bulb in response to natural stimulation was studied using application of different pharmacological substances. Three suppositions were checked up: 1) if the slow potential is of neuro-glial nature; 2) whether it reflects the primary afferent depolarization in the terminations of olfactory fibres which is responsible for the presynaptic inhibition in the olfactory bulb (as the dorsal root potential in the spinal cord); 3) if it reflects postsynaptic potentials. The slow potential was found to have many pharmacological properties similar to those of the dorsal root potential in the spinal cord. However, the slow potential appears to be more a complicated response and includes at least one more component--a depolarization of dendrites of unknown nature.
D000818:Animals; D001001:Anura; D002698:Chloralose / Q000494:pharmacology; D008564:Membrane Potentials / Q000187:drug effects*; D009020:Morphine / Q000494:pharmacology; D009830:Olfactory Bulb / Q000187:drug effects*; D010406:Penicillins / Q000494:pharmacology; D010424:Pentobarbital / Q000494:pharmacology; D010852:Picrotoxin / Q000494:pharmacology; D011896:Rana temporaria; D013331:Strychnine / Q000494:pharmacology; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology
D002698:Chloralose; D009020:Morphine; D010406:Penicillins; D010424:Pentobarbital; D010852:Picrotoxin; D013331:Strychnine; D005680:gamma-Aminobutyric Acid
Farmakologicheskiĭ analiz medlennogo potentsiala, voznikaiushchego v otvet na adekvatnoe razdrazhenie v oboniatel'noĭ lukovitse liagushki