title: Osteonecrosis following renal transplantation.
abstract: Subarticular osteonecrosis has been described with increasing frequency after renal transplantation and the use of immunosuppressive corticosteroids. Six cases have been encountered among 170 patients in the Johannesburg renal transplantation programme. The commonly affected sites are the femoral head, the femoral condyles, the humeral head, the talus and the capitulum. The radiological and morbid anatomical features of this complication are described, alternative theories of pathogenesis are considered and an approach to treatment is outlined.
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000328:Adult; D001847:Bone Diseases / Q000139:chemically induced* / Q000628:therapy; D005260:Female; D005269:Femur; D005270:Femur Head / Q000473:pathology; D005271:Femur Head Necrosis / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D006811:Humerus; D006962:Hyperparathyroidism, Secondary / Q000150:complications; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications; D011183:Postoperative Complications; D011859:Radiography; D014184:Transplantation, Homologous
chemical_list: D000305:Adrenal Cortex Hormones