title: The immune system of the nine-banded armadillo (Dasypus novemcinctus, Linn).
abstract: The armadillo is rapidly emerging as an animal for biomedical research. A morphological study of the immune system of the armadillo was undertaken to try to demonstrate a possible defect in the morphogenesis of the lymphoid organs that could account for their susceptibility to leprosy. Blood from 20 domesticated adult armadillos revealed lymphocytes predominated among circulating leukocytes in the majority of animals, whereas in wild animals neutrophils predominated. Necropsies revealed well-developed thymus glands and the thymus-dependent areas in lymph nodes and spleens contained abundant lymphoid cells. Hence, we conclude that the susceptibility of the armadillo to leprosy cannot be explained on a morphological basis.
mesh_terms: D000367:Age Factors; D000818:Animals; D001491:Basophils / Q000166:cytology; D001774:Blood Chemical Analysis; D004195:Disease Models, Animal; D006644:Histiocytes / Q000166:cytology; D007918:Leprosy / Q000276:immunology*; D007962:Leukocytes / Q000166:cytology; D008198:Lymph Nodes / Q000033:anatomy & histology; D008214:Lymphocytes / Q000166:cytology; D008221:Lymphoid Tissue / Q000033:anatomy & histology; D009166:Mycobacterium leprae / Q000472:pathogenicity; D009504:Neutrophils / Q000166:cytology; D013154:Spleen / Q000033:anatomy & histology; D013950:Thymus Gland / Q000033:anatomy & histology; D004490:Xenarthra / Q000033:anatomy & histology / Q000276:immunology*