title: The presence of IgA on the surface of rat thoractic duct lymphocytes which contain internal IgA.
abstract: The presence of lymphocytes with internal IgA among cells from rat thoracic duct lymph wdy. The number of cells detected was greater in animals kept in a convential animal house compared with those maintained under specific pathogen-free conditions. Thoracic duct lymph from B rats and adult thymectomized rats also contained cell with internal IgA. The surface Ig of the IgA-containing cells was studied using a double-labeling technique with (126I) anti-Ig to detect surface Ig, and fluorescein-conjugated anti-IgA  in large amounts, but very little IgM and no surface IgG2. The surface IgA was not acquired passively.
mesh_terms: D000818:Animals; D001345:Autoradiography; D002462:Cell Membrane / Q000276:immunology*; D005260:Female; D005455:Fluorescent Antibody Technique; D005856:Germ-Free Life; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007457:Iodine Radioisotopes; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D011817:Rabbits / Q000276:immunology; D051381:Rats; D011919:Rats, Inbred Strains; D013897:Thoracic Duct / Q000166:cytology*; D013934:Thymectomy
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007457:Iodine Radioisotopes