T and B lymphocyte subpopulations in children.
T and B lymphocyte subpopulations were examined in the peripheral blood of children using the E and EAC rosette assays. Children under 18 months of age were found to have a decreased percentage of E-binding (T) lymphocytes and an increased percentage of EAC-binding (B) lymphocytes compared to older children (18 months to 10 years) and adults. The absolute number of E-binding and EAC-binding lymphocytes was increased in children under 18 months of age.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000818:Animals; D001402:B-Lymphocytes / Q000032:analysis; D001666:Binding Sites, Antibody; D002648:Child; D002675:Child, Preschool; D005260:Female; D005455:Fluorescent Antibody Technique; D006652:Histological Techniques; D006801:Humans; D007104:Immune Adherence Reaction; D007109:Immunity; D007223:Infant; D008297:Male; D012756:Sheep; D013601:T-Lymphocytes / Q000032:analysis