Prospectives for cell and organ culture systems in the study of pancreatic carcinoma.
Adenocarcinoma of the pancreas is presumed to arise from ductal cell precursors. This brief article questions the definitions on which this assumption is based and suggests possible ways to answer the question since for future studies on the etiology of this cancer it is imperative to study the appropriate cell of origin. Possible approaches for future work on pancreatic carcinogenesis utilizing cell and organ culture systems are discussed.
D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology; D002454:Cell Differentiation; D002478:Cells, Cultured; D006801:Humans; D009924:Organ Culture Techniques; D010183:Pancreatic Ducts / Q000166:cytology*; D010190:Pancreatic Neoplasms / Q000209:etiology* / Q000473:pathology