Chloramphenicol stimulation of lysogeny by lambda regulatory mutants.
Inhibition of protein synthesis in Escherichia coli by amino acid starvation or chloramphenicol addition increases the frequency of lysogeny by lambda phage two- to fourfold. Lambda cIII mutants, which normally lysogenize at very low frequencies, lysogenize at very high frequencies in the presence of chloramphenicol.
D001426:Bacterial Proteins / Q000096:biosynthesis; D002701:Chloramphenicol / Q000494:pharmacology*; D003090:Coliphages / Q000254:growth & development*; D004926:Escherichia coli / Q000378:metabolism; D008242:Lysogeny / Q000187:drug effects*; D008715:Methionine / Q000378:metabolism; D009154:Mutation; D013268:Stimulation, Chemical; D014633:Valine / Q000378:metabolism
D001426:Bacterial Proteins; D002701:Chloramphenicol; D008715:Methionine; D014633:Valine