title: B and T lymphocytes in man. III. B, t, and "null" lymphocytes in multiple sclerosis.
abstract: T, B, and "null" lymphocytes were determined in peripheral blood obtained from 24 control subjects and 15 multiple sclerosis patients. The total number of lymphocytes and T lymphocytes were reduced significantly in multiple sclerosis patients as compared with those of controls. Although the percentage of B lymphocytes increased in these patients, the absolute number of B lymphocytes was similar to controls. The mitotic response of lymphocytes from multiple sclerosis patients to phytohemagglutinin and pokeweed mitogen in 7-day-old cultures was decreased as compared with that of controls.
mesh_terms: D000328:Adult; D001402:B-Lymphocytes; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes; D008297:Male; D008875:Middle Aged; D008938:Mitosis; D009103:Multiple Sclerosis / Q000097:blood / Q000276:immunology*; D013601:T-Lymphocytes