Repair of ultraviolet irradiation damage to a cytoplasmic component required for neural induction in the amphibian egg.
Localized ultraviolet irradiation of the amphibian egg destroys a cytoplasmic component that is required for neural induction. Destruction of that component severely diminishes the inducing capacity of the dorsal lip at gastrulation, as determined by embryological assays. Repair of the ultraviolet lesion can be achieved by replacing the dorsal lip of the irradiated embyro with a lip from an unirradiated embryo.
D000818:Animals; D002454:Cell Differentiation / Q000528:radiation effects*; D003593:Cytoplasm / Q000528:radiation effects; D004625:Embryo, Nonmammalian; D004627:Embryonic Induction / Q000528:radiation effects*; D005260:Female; D009417:Nerve Tissue / Q000528:radiation effects* / Q000637:transplantation; D010063:Ovum / Q000528:radiation effects*; D011830:Radiation Effects; D011894:Rana pipiens; D014184:Transplantation, Homologous; D014466:Ultraviolet Rays