Absence of luteinizing hormone-releasing hormone (LH-RH) from catecholaminergic neurons.
6-Hydroxy-dopamine was administered into the third ventricle of adult male rats. After 2 successive 250 mug doses of 6-OH-dopamine, the levels of norepinephrine and dopamine in the median eminence and arcuate nucleus fell to 15-20% of the control value. The amount of luteinizing hormone releasing hormone (LH-RH) in these same hypothalamic areas, however, was unchanged. It is concluded that LH-RH containing cells are distinct from catecholaminergic neurons.
D000818:Animals; D004298:Dopamine / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone / Q000378:metabolism*; D006892:Hydroxydopamines / Q000494:pharmacology; D008297:Male; D008473:Median Eminence / Q000166:cytology; D009474:Neurons / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D013787:Thalamic Nuclei / Q000166:cytology
D006892:Hydroxydopamines; D007987:Gonadotropin-Releasing Hormone; D004298:Dopamine; D009638:Norepinephrine