title: Investigation of luteinizing-inducing effect of pinealectomy or thyroidectomy in different types of anovulatory syndromes in rats.
abstract: The luteinizing-inducing effect of pinealectomy and of thyroidectomy was investigated in the constant estrous anovulatory (CEA) syndrome caused either by frontal hypothalamic deafferentation (FHD) or by neonatal androgen treatment (NA). Thyroidectomy failed to induce luteinization in both types of CEA syndrome. However, pinealectomy provoked the formation of corpora lutea in FHD, but not in NA induced CEA syndrome. It was concluded that the luteinizing-inducing effect of pinealectomy is a specific consequence of the removal of the pineal hormone-like principles. The differences in the mechanism of development of the CEA syndrome following FHD or NA might account for the failure of pinealectomy to elicite luteinization in the NA induced CEA rat.
mesh_terms: D000818:Animals; D000858:Anovulation / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D003338:Corpus Luteum / Q000503:physiopathology*; D005260:Female; D007032:Hypothalamus, Anterior / Q000601:surgery; D009929:Organ Size; D010053:Ovary / Q000033:anatomy & histology; D010870:Pineal Gland / Q000601:surgery*; D051381:Rats; D013739:Testosterone; D013965:Thyroidectomy; D014621:Vagina / Q000473:pathology
chemical_list: D013739:Testosterone