In vitro metabolic activation of chemical mutagens. II. The relationships among mutagen formation, metabolism and carcinogenicity for dimethylnitrosamine and diethylnitrosamine in the livers, kidneys and lungs of BALB/cJ, C57BL/6J and RF/J mice.
D000818:Animals; D002273:Carcinogens; D004052:Diethylnitrosamine / Q000378:metabolism*; D004128:Dimethylnitrosamine / Q000378:metabolism*; D005260:Female; D007668:Kidney / Q000378:metabolism / Q000648:ultrastructure; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism / Q000648:ultrastructure; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D008861:Microsomes / Q000378:metabolism; D008862:Microsomes, Liver / Q000378:metabolism; D009153:Mutagens; D009602:Nitrosamines / Q000378:metabolism*; D012486:Salmonella typhimurium
D002273:Carcinogens; D009153:Mutagens; D009602:Nitrosamines; D004052:Diethylnitrosamine; D004128:Dimethylnitrosamine