Effects of disintegration of incorporated 35S on mutation frequency.
The reverse mutation to the wild type of lambda sus 9 and T4 AM B17 bacteriophages, grown in bacteria prelabeled with 35S and stored at--196 degrees, was studied. No mutagenic effect of 35S was observed in both, lambda and T4 bacteriophages. It is suggested that there is no influence of 35S disintegrations on the properties of DNA polymerase to which the mutagenic activity could be attributed.
D003090:Coliphages / Q000201:enzymology / Q000378:metabolism / Q000528:radiation effects*; D004254:DNA Nucleotidyltransferases / Q000378:metabolism / Q000528:radiation effects; D004261:DNA Replication; D004267:DNA Viruses; D004279:DNA, Viral / Q000096:biosynthesis; D004926:Escherichia coli / Q000201:enzymology; D005615:Freezing; D009154:Mutation; D011487:Protein Conformation / Q000528:radiation effects; D011830:Radiation Effects; D013462:Sulfur Radioisotopes
D004279:DNA, Viral; D013462:Sulfur Radioisotopes; D004254:DNA Nucleotidyltransferases