Effect of continuous positive pressure ventilation on cardiac output.
Ten mongrel dogs were placed on 5 and 10 cm. H20 of CPPV. Cardiac output, pulmonary vascular resistance and pleural pressures were measured. At 5 cm. H20/CPPV there was no significant change in cardiac output or pulmonary vascular resistance. At 10 cm. H20 CPPV cardiac output significantly decreased and pulmonary vascular resistance increased. The physiologic basis for these changes is discussed and related to the clinical situation.
D000818:Animals; D001794:Blood Pressure; D002302:Cardiac Output; D004285:Dogs; D007201:Indicator Dilution Techniques; D010994:Pleura; D011175:Positive-Pressure Respiration; D011312:Pressure; D011652:Pulmonary Circulation; D014655:Vascular Resistance