[Quantitative characteristics of the migration ability of different types of fibroblast-like cells cultured on substrates with an ordered relief].
Reactions to the geometrical configuration of the underlying surface of fibroblast-like cells of various species (mouse, rat, chick, hamster, human) were compared quantitatively. All normal cells migrated from 25-40 mcm deep grooves but not from the less deep ones -5-15 mcm. Migration ability was the highest in the mouse cells;it was less pronounced in rat and chick cells; hamster and human cells had the lowest migration ability. The offered quantitative method can be used for estimation of the reaction to the ordered relief of the substratum of different minds of cultured cells - normal as well as pathologically changed.
D000818:Animals; D002452:Cell Count; D002465:Cell Movement; D002478:Cells, Cultured / Q000502:physiology*; D002642:Chick Embryo; D006224:Cricetinae; D003470:Culture Media; D003584:Cytological Techniques; D005347:Fibroblasts / Q000502:physiology*; D006801:Humans; D051379:Mice; D008853:Microscopy; D051381:Rats; D013045:Species Specificity; D013997:Time Factors
D003470:Culture Media
Kolichestvennaia kharakteristika migratsionnoĭ sposobnosti razlichnykh vidovfibroblastopodobnykh kletok, kul'tiviruemykh na podlozhkakh s uporiadochennym rel'efom