title: Mutations in the new gene stIII of bacteriophage T4B suppressing the lysis defect of gene stII and a gene e mutant.
abstract: Mutations of bacteriophage T4B were found which suppress the lysis defect of both gene stII mutants and gene e mutants. The suppressor mutations belong to a new gene, stIII, of phage T4B. Gene stIII is located on the genetic map of T4B between genes stI and e. stIII mutants sometimes form star plaques on Escherichia coli B. The latent period on E. coli 594, but not E. coli B, is shorter with stIII mutants than that with wild-type phage. The premature lysis of E. coli 594 infected with stIII phage does not depend on the expression of both stII+ and e+ function. StIII allele is dominant over the stIII+ with respect to both the ability to suppress the stII defect and the early lysis of infected E. coli 594 cultures.
mesh_terms: D000483:Alleles; D000596:Amino Acids / Q000378:metabolism; D001433:Bacteriolysis; D002250:Carbon Radioisotopes; D002874:Chromosome Mapping; D003090:Coliphages / Q000254:growth & development; D003433:Crosses, Genetic; D004267:DNA Viruses; D004926:Escherichia coli / Q000378:metabolism; D005799:Genes, Dominant; D005816:Genetic Complementation Test; D009154:Mutation; D010539:Permeability; D013489:Suppression, Genetic
chemical_list: D000596:Amino Acids; D002250:Carbon Radioisotopes