title: Increased affinity of guinea pig thymocytes and thymus-dependent lymphocytes for papain-treated rabbit erythrocytes compared to untreated erythrocytes.
abstract: The affinity of guinea pig thymocytes and peripheral T lymphocytes for rabbit erythrocytes was found to be enhanced following treatment of the erythrocytes with papain. By increasing the numbers of rosette-forming cells and giving stronger, more stable rosettes, this procedure increases the usefulness of the reaction as a T cell marker in guinea pigs.
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D003298:Coombs Test; D004912:Erythrocytes / Q000187:drug effects / Q000276:immunology*; D006168:Guinea Pigs; D007104:Immune Adherence Reaction / Q000379:methods*; D008198:Lymph Nodes / Q000166:cytology; D008214:Lymphocytes / Q000276:immunology*; D010206:Papain / Q000494:pharmacology*; D011817:Rabbits / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland / Q000166:cytology
chemical_list: D010206:Papain