Age-related interrelationships of blood pressure and arterial sterol accumulation in spontaneously atherosclerosis-susceptible and atherosclerosis-resistant pigeons.
Interrelationships of arterial sterol accumulation and blood pressures were examined in age-matched White Carneau and Show Racer pigeons. It was found that the systolic blood pressure of White Carneaux changed from 155.0 mm Hg at nine months of age to 168.8 mm Hg at 17 months of age (P less than 0.005) while that of the Show Racers did not show any age-related increases. In White Carneaux, the total sterol content in the aorta increased by 43.6% from 9 months to 17 months of age (P less than 0.001) with major changes in the steryl ester fraction while no such changes were evident in the Show Racers. This indicates interrelationships of the arterial sterol content and blood pressure in the White Carneau pigeon.
D000375:Aging; D000818:Animals; D001011:Aorta / Q000032:analysis*; D001161:Arteriosclerosis / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology*; D001794:Blood Pressure; D010856:Columbidae; D013261:Sterols / Q000032:analysis*
D013261:Sterols