[Quantitative determination of alpha1-antitrypsin in lung tissue from adults with emphysema and newborns with respiratory-distress-syndrome (author's transl)].
In a small number of patients, lung emphysema can be attributed to a remarkable deficiency of alpha1-antitrypsin. Concentrations reduced about 50% of the normal value represent a predisposing factor. In most cases of newborns with respiratory-distress-syndrome the concentration of alpha1-antitrypsin is decreased. Its determination can be used for the early diagnosis of the respiratory-distress-syndrome.
D000328:Adult; D000367:Age Factors; D006801:Humans; D007231:Infant, Newborn; D008099:Liver / Q000201:enzymology; D011656:Pulmonary Emphysema / Q000201:enzymology; D012127:Respiratory Distress Syndrome, Newborn / Q000201:enzymology*; D000515:alpha 1-Antitrypsin / Q000378:metabolism*
D000515:alpha 1-Antitrypsin
Quantitative Bestimmungen von Alpha1-Antitrypsin im Lungengewebe von Emphysematikern und Neugeborenen Atemnotsyndrom