title: Preservation of kidneys for transplantation. Assessment of ischemic damage by renal autoperfusion.
abstract: Autoperfusion of canine kidneys was investigated as an alternative method to determinate the ischmic organ damage following various preservation procedures. As a compromise between implantation of the donor kidney and normotherimic isolated perfusion, autoperfusion is shown to offer some advantages in the study of the pathophysiology of the ischemic damaged kidney. Within 3 hours of autoperfusion, we obtained detailed information about the immediate regenerative ability of the glomerular, tubular, and vascular functions following various sorts of ischemic trauma.
mesh_terms: D000818:Animals; D003404:Creatinine / Q000652:urine; D004285:Dogs; D005260:Female; D007511:Ischemia; D007668:Kidney / Q000098:blood supply; D016030:Kidney Transplantation; D008297:Male; D009926:Organ Preservation / Q000379:methods*; D010477:Perfusion; D012039:Regional Blood Flow; D013696:Temperature; D014021:Tissue Preservation / Q000379:methods*; D014184:Transplantation, Homologous; D014655:Vascular Resistance
chemical_list: D003404:Creatinine