[Influence of occlusion of retinal vessels on the transport of 22Na and 131J-iodo-o-hippurate out of the subretinal space (experiments performed on cats) (author's transl)].
By means of microsurgical technique and under the control of the ophthalmoscope 300 mul of isotone solution of NaCl with 22Na or o-131J-iodo-hippuric acid were injected into the space between the retina and pigment epithelium of 28 narcotized tomcats after having closed the inferior retina vessels by photocoagulation about 1 hr before in an umber of the animals. With 22Na we could demonstrate that the retinal vessels influence the speed of the transport of substances out of the space between retina and pigment epithelium: When the retina vessels are closed, the transport is decelerated. The same experiments with o-131J-iodo-hippuric acid did not show any difference between the eyes with coagulated vessels and those with open ones. We cannot answer the question, whether sodium is transported in a mono-directional flux out of the space between retina and pigment epithelium (probably followed by water), or if there is simply an exchange between 22Na out of this space with 22Na of the blood.
D000818:Animals; D001082:Aqueous Humor / Q000378:metabolism; D001692:Biological Transport; D002415:Cats; D007457:Iodine Radioisotopes; D007465:Iodohippuric Acid / Q000378:metabolism*; D008028:Light Coagulation; D008297:Male; D008657:Metabolic Clearance Rate; D012160:Retina / Q000378:metabolism; D012163:Retinal Detachment / Q000378:metabolism / Q000503:physiopathology*; D012171:Retinal Vessels / Q000502:physiology*; D012965:Sodium Chloride / Q000378:metabolism*; D012979:Sodium Radioisotopes; D014822:Vitreous Body / Q000378:metabolism
D007457:Iodine Radioisotopes; D012979:Sodium Radioisotopes; D007465:Iodohippuric Acid; D012965:Sodium Chloride
Einfluss von Netzhautgefässverschlüssen auf den Abtransport von 22Na und o-131J-Hippursäure aus dem Raume zwischen Netzhaut und Pigmentepithel (Katzenversuche)