[Cellular immune reactions of the white mouse after superinfection with Toxoplasma gondii (author's transl)].
After superinfection of immunized mice with a virulent strain of Toxoplasma (BK) these mice don't die. There is formation of a cellrich exudate with only very few toxoplasmas. The number of the different exudate-cells (macrophages, big, middlesized and small lymphocytes and heterophils) turn in direction of the lymphocytes in that way, that after the 3rd day of infection 70% of all exudate-cells belong to the group of lymphocytes. They seem to cause the death of the toxoplasmas. After in vitro incubation of trophozoites and exudate-cells of immune mice for 2 hours at 37 degrees C nearly 80% of the added toxoplasmas are killed. Electronmicroscopical pictures show, that this killing is produced by a process of lysis.
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D006098:Granulocytes / Q000276:immunology; D007111:Immunity, Cellular; D007114:Immunization; D008214:Lymphocytes / Q000276:immunology / Q000648:ultrastructure; D008264:Macrophages / Q000276:immunology; D051379:Mice; D013601:T-Lymphocytes / Q000276:immunology; D013696:Temperature; D014122:Toxoplasma / Q000472:pathogenicity / Q000648:ultrastructure; D014124:Toxoplasmosis, Animal / Q000276:immunology*
Zelluläre Immunreaktionen bei der weissen Maus nach Superinfektion mit Toxoplasma gondii