Kuru-plaques in creutzfeldt-jakob disease.
A case of Creutzfeldt-Jakob disease of cerebellar type is reported. In this case the cerebellar cortex exhibited classical Kuru-plaques. From a comparison of this finding with 50 cerebella from senile patients and patients with cerebellar atrophies it is concluded that the Kuru-plaque is specific for Creutzfeldt-Jakob disease, possible even for its cerebellar variant.
D000368:Aged; D002525:Cerebellar Cortex / Q000473:pathology*; D007562:Creutzfeldt-Jakob Syndrome / Q000473:pathology*; D005260:Female; D006801:Humans; D007729:Kuru / Q000473:pathology*; D011689:Purkinje Cells / Q000648:ultrastructure