A micro-rosette test for newborns.
It is known that human T-cells can be identified by rosette formation with sheep red blood cells. The authors have developed a micro adaptation of the rosette-forming cell test with which they compared the lymphocyte distribution of 38 newborns to that of 42 older children. The percentage of lymphocytes spontaneously forming rosettes was similar in the two groups. Absolute lymphocyte counts were also similar. They suggest that this micro-rosette test could offer the clinician a rapid and inexpensive laboratory method of assessing cell-mediate immunity in the neonate.
D006801:Humans; D007104:Immune Adherence Reaction / Q000379:methods*; D007111:Immunity, Cellular; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000276:immunology*; D013601:T-Lymphocytes / Q000032:analysis*