Induction of secondary cytotoxic T-lymphocytes in vitro does not require cell proliferation.
Using a mouse in vitro allograft model, evidence has been obtained that, in contrast to the accepted view, the generation of cytotoxic effector function in T-lymphocytes does not necessarily require cell division.
D000818:Animals; D002455:Cell Division; D003601:Cytotoxicity Tests, Immunologic; D006649:Histocompatibility Antigens; D007156:Immunologic Memory; D051379:Mice; D008815:Mice, Inbred Strains; D008937:Mitomycins / Q000494:pharmacology; D013601:T-Lymphocytes / Q000276:immunology*
D006649:Histocompatibility Antigens; D008937:Mitomycins