title: Clinical trial of a low dose combined oral contraceptive ('Ovranette').
abstract: A combination of 150 mug. d-norgestrel with 30 mug. ethinyl oestradiol was administered to 120 women for a total of 767 cycles. No pregnancies occurred and cycle control was good, 99% of the cycles being within the range of 28 plus or minus 3 days. Breakthrough bleeding occurred in 7.2% of the cycles, spotting in 8.9% and amenorphoea in 0.8%. Side-effects were minimal.
mesh_terms: D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D003276:Contraceptives, Oral / Q000008:administration & dosage*; D003278:Contraceptives, Oral, Hormonal / Q000008:administration & dosage*; D004338:Drug Combinations; D004997:Ethinyl Estradiol / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008598:Menstruation / Q000187:drug effects; D009644:Norgestrel / Q000008:administration & dosage*; D011247:Pregnancy / Q000187:drug effects
chemical_list: D003276:Contraceptives, Oral; D003278:Contraceptives, Oral, Hormonal; D004338:Drug Combinations; D009644:Norgestrel; D004997:Ethinyl Estradiol