Stimulation of lymphocytes by purified protein derivative: suppression by cells from human vaccinated with Bacille Calmette-Guérin.
Specific stimulation of thymus-derived cells by purified protein derivative or tetanus toxoid was inhibited by autologous lymphocytes. The lymphocytes, which were collected from healthy humans who had been vaccinated with bacille Calmette-Guérin were purified on nylon columns after removal of cells that form rosettes with sheep erythrocytes. The degree of purification of the lymphocytes was controlled by appropriate techniques.
D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D001500:BCG Vaccine; D006801:Humans; D007104:Immune Adherence Reaction; D007165:Immunosuppression Therapy; D008213:Lymphocyte Activation; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D013745:Tetanus Toxoid / Q000494:pharmacology; D014374:Tuberculin Test
D001500:BCG Vaccine; D013745:Tetanus Toxoid