Neonatal Haemophilus influenzae infection. Report of eight cases and review of the literature.
Eight cases of neonatal Haemophilus influenzae infection occurred at Colorado General Hospital during a 3 1/2-year period. Four of the cases were due to nontypable organisms and four to type b organisms. Four were bacteremic, only two of which were type b. None of the patients had meningitis. In all instances, maternal genital tract cultures yielded H infleuzae that, when tested, was of the same serotype as the infant isolate. A survey of cervical cultures among normal and pregnant women yielded H influenzae in less than 1%. There are several possible reasons for the disparity between the apparent high incidence of neonatal infection and low prevalence of maternal carriage.
D000293:Adolescent; D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000032:analysis; D000942:Antigens, Bacterial / Q000032:analysis; D002584:Cervix Uteri / Q000382:microbiology; D005260:Female; D005836:Genitalia, Female / Q000382:microbiology; D006192:Haemophilus Infections / Q000151:congenital* / Q000188:drug therapy; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D000667:Ampicillin