title: Treatment of acute respiratory tract infections with doxycycline in general practice.
abstract: A multi-centre general practitioner trial was carried out in the Netherlands during the winter of 1973/1974. This trial was part of a larger pan-European study. There were 13- cases studied in the Netherlands who were only treated with doxycycline, by 17 physicians. All patients included in the trial had an acute infection of either the upper or lower respiratory tract. tthere were 64 females and 66 males. The results were excellent at 100 patients (76.9%) had a very good result, 21 patients (16.2%) had moderate or fair results, and only 7 patients (5.4%) had poor or negative results. Doxycycline was well tolerated as no side-effects were noted in 122 of the patients (93.8%). In the 8 patients who experienced side-effects they were mild and self-limiting.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D001991:Bronchitis / Q000188:drug therapy; D001996:Bronchopneumonia / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004318:Doxycycline / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D010612:Pharyngitis / Q000188:drug therapy; D011014:Pneumonia / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D012852:Sinusitis / Q000188:drug therapy; D014069:Tonsillitis / Q000188:drug therapy; D014136:Tracheitis / Q000188:drug therapy
chemical_list: D004318:Doxycycline