[Research on the effectiveness of gynecological prescreening (author's transl)].
Malignant tumors are determined by abnormal values of DNA as well as in its precursors. The cytophotometric analysis of smears allowed the determination of DNA of higher number of cells and therefore was presented as prescreening. But higher amounts of DNA caused by colpitis was reached too in this case. Therefore the presented research tried to limit points of malignancy by determination ofDNA, RNA, Histones, and Heterochromatin of cytologically classified cells. The discussion of results with literature pointed out, that this object is only reaching today by simultaneous determination of DNA and Heterochromatin of selected "atypical" cells.
D001634:Bibliographies as Topic; D002277:Carcinoma / Q000175:diagnosis; D002278:Carcinoma in Situ / Q000175:diagnosis; D002908:Chronic Disease; D004273:DNA, Neoplasm / Q000032:analysis*; D003937:Diagnosis, Differential; D004171:Diploidy; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006570:Heterochromatin / Q000032:analysis*; D006651:Histocytochemistry; D006657:Histones / Q000032:analysis; D006801:Humans; D008403:Mass Screening; D010783:Photometry; D011123:Polyploidy; D012334:RNA, Neoplasm / Q000032:analysis; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*; D014594:Uterine Neoplasms / Q000175:diagnosis*; D014626:Vaginal Smears / Q000379:methods*; D014627:Vaginitis / Q000175:diagnosis
D004273:DNA, Neoplasm; D006570:Heterochromatin; D006657:Histones; D012334:RNA, Neoplasm
Untersuchungen über die Effektivität der halbautomatischen gynäkologischen Krebsvorsorge