Nerve excitation generated by the action potential of muscle.
The effect of the electrical activity of muscle on the nerve in contact with it was investigated. The results obtained on isolated nerve-muscle preparations and on whole leg preparations of frog revealed that, under certain conditions, the action potential of the muscle is capable of producing excitation of the nerve adjacent to the muscle. These results suggest the hypothesis that the muscle activity could have an additional function in the excitatory processes by means of the electrical effect exerted on the nerve.
D000200:Action Potentials; D000818:Animals; D009119:Muscle Contraction; D009132:Muscles / Q000502:physiology*; D009469:Neuromuscular Junction / Q000502:physiology; D010525:Peripheral Nerves / Q000502:physiology*; D011893:Rana esculenta