The "fetoscope"--a new clinical tool for prenatal genetic diagnosis.
Our experience in 65 patients using a "fetoscope" and local anesthesia prior to saline abortion is described. Visualization of the intrauterine contents improved with experience, was optimum at 16 to 18 weeks' gestation, and was superior to the quality of photographic records. Four fetal skin biopsies and 6 amnion biopsies were done. Six blood samples were taken from the fetal surface of the placenta. The limitations of this instrument are described. No significant complications have occurred. Current and probable future indications for fetoscopy are reviewed. Until both the safety of the procedure is proved and problems of visualization due to limitation of visual field are solved, extreme caution is urged in the employment of this instrument in genetic high-risk pregnancy.
D000032:Abortion, Therapeutic; D000650:Amnion / Q000033:anatomy & histology; D000653:Amniotic Fluid / Q000502:physiology; D001706:Biopsy; D001707:Biopsy, Needle; D019723:Endoscopes; D005260:Female; D005333:Fetus / Q000033:anatomy & histology; D005336:Fiber Optic Technology / Q000295:instrumentation*; D005386:Fingersucking; D005817:Genetic Counseling; D006801:Humans; D007263:Infusions, Parenteral; D010920:Placenta / Q000033:anatomy & histology; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis / Q000295:instrumentation*; D012732:Sex Determination Analysis / Q000295:instrumentation; D014463:Ultrasonography; D014470:Umbilical Cord / Q000033:anatomy & histology