title: Use of the K88 antigen for in vivo bacterial competition with porcine strains of enteropathogenic Escherichia coli.
abstract: Infant mice were used to measure the amount of fluid accumulation (enterosorption) in the intestinal tract after oral inoculation of a porcine strain of enteropathogenic Escherichia coli (K88-+, Ent-+). Significant reduction in the amount of fluid found in the intestinal tract was observed if the mice were first inoculated with a K88-possessing, non-enterotoxigenic strain of E. coli. The protection provided is thought to be due to specific competition for attachment sites on cells of the small intestine.
mesh_terms: D000372:Agglutination Tests; D000818:Animals; D000942:Antigens, Bacterial; D001667:Binding, Competitive; D003106:Colon / Q000382:microbiology; D004768:Enterotoxins; D004926:Escherichia coli / Q000254:growth & development / Q000276:immunology* / Q000302:isolation & purification; D005260:Female; D007421:Intestine, Small / Q000276:immunology; D007583:Jejunum / Q000382:microbiology; D008297:Male; D051379:Mice; D013045:Species Specificity; D013552:Swine
chemical_list: D000942:Antigens, Bacterial; D004768:Enterotoxins