Intracranial pressure during ventriculography using meglumine iothalamate.
A small increase in ventricular fluid pressure (1.3 +/- 0.3 mm Hg) occurs on isovolumetic addition of meglumine iothalamate to the lateral ventricle. A marked increase (46.3 +/- 3.2 mm Hg: P less than 0.001) in pressure occurs on passage of the contrast medium into the posterior part of the third ventricle; the aqueduct and the fourth ventricle. Theoretical mechanisms are discussed.
D000368:Aged; D001812:Blood-Brain Barrier / Q000187:drug effects; D014695:Cerebral Ventriculography; D005260:Female; D006801:Humans; D007223:Infant; D007427:Intracranial Pressure / Q000187:drug effects*; D007482:Iothalamate Meglumine / Q000494:pharmacology*; D007483:Iothalamic Acid / Q000031:analogs & derivatives*; D008297:Male; D011187:Posture
D007483:Iothalamic Acid; D007482:Iothalamate Meglumine