Fat embolism: physiopathology, diagnosis with management.
This paper describes the components of the post-traumatic syndrome. The pathological state of fat macroglobulinemia by occlusion of arteriolar terminal branches of vital organs causes the fat embolic syndrome. The main physiopathological problem is pulmonary insufficiency in an acute or subacute form. The cerebral embolus is second. The symptomatology varies and is not characteristic. According to their importance they were described as minor or major in the diagnosis of fat emboli. Only recently, treatment for the fat emboli syndrome has been initiated, consisting mainly in supportive measures, respiratory care and anti-inflammatory drugs, mainly cortisone.
D007611:Aprotinin / Q000627:therapeutic use; D003348:Cortisone / Q000627:therapeutic use; D003911:Dextrans / Q000627:therapeutic use; D004620:Embolism, Fat / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000503:physiopathology; D011175:Positive-Pressure Respiration; D011655:Pulmonary Embolism / Q000503:physiopathology; D012121:Respiration, Artificial; D013577:Syndrome; D014947:Wounds and Injuries / Q000150:complications*
D003911:Dextrans; D006493:Heparin; D007611:Aprotinin; D003348:Cortisone