title: Immune response to Escherichia coli.
abstract: Chickens from a line artifically selected for lew level of plasma corticosterone (LPC) produced higher antibody titers, produced antibody earlier, continued the production of antibody longer, responded to lower dosages of antigen, and had greater body weight gain than those from a line slected for a high level of plasma corticosterone (hpc). the HPC line resisted Escherichia coli challenge and antigen more effectively than the LPC line. It appears that, although the HPC line is more effective in its defense against bacterial infections, the LPC line can be aided more by vaccines.
mesh_terms: D000372:Agglutination Tests; D000400:Air Sacs; D000818:Animals; D000917:Antibody Formation; D000942:Antigens, Bacterial / Q000008:administration & dosage; D001428:Bacterial Vaccines / Q000008:administration & dosage; D002645:Chickens / Q000276:immunology*; D003345:Corticosterone / Q000097:blood; D004926:Escherichia coli / Q000276:immunology*; D004927:Escherichia coli Infections / Q000276:immunology / Q000503:physiopathology / Q000662:veterinary; D007267:Injections; D007274:Injections, Intraperitoneal; D007275:Injections, Intravenous; D011201:Poultry Diseases / Q000276:immunology / Q000503:physiopathology; D012641:Selection, Genetic
chemical_list: D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D003345:Corticosterone