Portal hypertension in children following neonatal umbilical disorders.
10 children presented pre-hepatic portal vein obstruction during their first 6 years of life. 8 of them had massive esophageal varices, 1 died from acute esophageal hemorrhage. The perinatal history of these childre was studied: All of them had an abnormal birth history and all had been hospitalized during their neonatal period. In 5 of them an umbilical infection had been diagnosed, one had an injection of THAM and one other an exchange transfusion through an umbilical vein catheter. Pre-hepatic portal vein occlusion in children is presumed to be mainly an acquired disease resulting from neonatal umbilical disorders.
D002648:Child; D002675:Child, Preschool; D003250:Constriction; D004935:Esophageal Diseases / Q000209:etiology; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications / Q000209:etiology* / Q000517:prevention & control; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D007239:Infections / Q000150:complications; D008297:Male; D011169:Portal Vein; D014470:Umbilical Cord