[Treatment of psoriasis with an orally administered effective new vitamin A acid derivative. Preliminary report].
The retinoic acid derivative Ro 10-9359 has been tested in 24 patients with psoriasis. In all patients the therapeutic activity was good to excellent. The symptoms of the hypervitaminosis A syndrome were slight to marked. The ratio between the therapeutic effectiveness and the side effects was favourable only in cases with severe psoriasis.
D000284:Administration, Oral; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D006197:Hair / Q000187:drug effects; D006801:Humans; D009262:Nails / Q000187:drug effects; D010919:Placebos; D011565:Psoriasis / Q000188:drug therapy*; D013997:Time Factors; D014212:Tretinoin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014801:Vitamin A / Q000031:analogs & derivatives*
D010919:Placebos; D014801:Vitamin A; D014212:Tretinoin
Therapie der Psoriasis mit einem oral wirksamen neuen Vitamin-A-Säure-Derivat. Vorläufige Mitteilung