title: [The effect of ischemic and cardioplegic heart standstill on the myocard metabolism in normal and less perfused heart (author's transl)].
abstract: The tolerance of ischemia in normal and less perfused myocard during an ischemic and cardioplegic heart standstill was investigated. A decrease of ATP and ADP and an increase of the lactate, pyruvate and AMP was established during an ischemia of 20 minutes. The less perfused hearts gave considerably worse results regarding the energy transformation than normal hearts. In less perfused hearts the energy reserve of myocardial metabolism showed a considerably better behaviour during a cardioplegic heart standstill of 45 minutes than an ischemic one of 20 minutes. During the recuperation period this trend was emphasised.
mesh_terms: D000244:Adenosine Diphosphate / Q000378:metabolism; D000249:Adenosine Monophosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D003326:Coronary Circulation; D004285:Dogs; D005958:Glucosephosphates / Q000378:metabolism; D006323:Heart Arrest / Q000378:metabolism*; D006324:Heart Arrest, Induced; D006352:Heart Ventricles / Q000378:metabolism; D007511:Ischemia / Q000378:metabolism; D007773:Lactates / Q000378:metabolism; D009206:Myocardium / Q000032:analysis / Q000378:metabolism*; D010477:Perfusion; D011773:Pyruvates / Q000378:metabolism; D013997:Time Factors
chemical_list: D005958:Glucosephosphates; D007773:Lactates; D011773:Pyruvates; D000249:Adenosine Monophosphate; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate
vernacular_title: Die Wirkung des ischämischen und kardioplegischen Herzstillstandes auf den Myokardstoffwechsel bei gesunden und minderdurchbluteten Herzen