Distribution and properties of glucagon immunoreactivity in the digestive tract of various mammals: an immunohistochemical and immunochemical study.
Numerous epithelial cells in the oxyntic gland area of the stomach of cat and dog appear to store pancreatic-type glucagon, as evidenced by immunohistochemistry and--in the case of the dog--also by radioimmunoanalysis. No glucagon immunoreactive cells are found in the antropyloric mucosa. Disseminated cells in the intestinal mucosa store gut-type glucagon. In all species studied, these cells predominate in ileum and colon.
D000818:Animals; D000937:Antigen-Antibody Reactions; D003106:Colon / Q000276:immunology; D004064:Digestive System / Q000276:immunology*; D004285:Dogs; D004386:Duodenum / Q000276:immunology; D005260:Female; D005455:Fluorescent Antibody Technique; D005753:Gastric Mucosa / Q000276:immunology; D005768:Gastrointestinal Hormones / Q000276:immunology; D005934:Glucagon / Q000276:immunology*; D006651:Histocytochemistry; D007082:Ileum / Q000276:immunology; D007413:Intestinal Mucosa / Q000276:immunology; D007583:Jejunum / Q000276:immunology; D008297:Male; D009928:Organ Specificity; D011708:Pylorus / Q000276:immunology; D011863:Radioimmunoassay; D051381:Rats; D013045:Species Specificity; D013552:Swine
D005768:Gastrointestinal Hormones; D005934:Glucagon