Some characteristics of human rosette-forming cells.
Some evidence for identification of human rosette-forming cells as thymus and thymus-dependent lymphocytes (T cells) is presented. Application of the rosette assay to several clinical conditions including primary immunodeficiency diseases indicates the usefulness of this assay in quantitating the number of T cells in peripheral blood.
D000818:Animals; D000961:Antilymphocyte Serum; D001379:Azathioprine / Q000627:therapeutic use; D001402:B-Lymphocytes / Q000276:immunology; D002469:Cell Separation; D003165:Complement System Proteins; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D007104:Immune Adherence Reaction; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis*; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation; D037102:Lectins; D008213:Lymphocyte Activation; D011241:Prednisone / Q000627:therapeutic use; D012756:Sheep / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D013936:Thymidine / Q000378:metabolism; D014184:Transplantation, Homologous; D014316:Tritium
D000961:Antilymphocyte Serum; D037102:Lectins; D014316:Tritium; D003165:Complement System Proteins; D001379:Azathioprine; D011241:Prednisone; D013936:Thymidine