title: Virologic and serologic studies of zoo birds for Marek's disease virus infection.
abstract: One hundred and eleven zoo birds representing 49 species in 14 orders were examined for Marek's disease (MD) herpesvirus (MDHV) infection. MDHV was isolated from 10 birds, all belonging to genus Gallus. The precipitating antibodies against MDHV were demonstrated only in the Gallus birds, when 51 selected birds including 34 Galliformes and 17 other birds representing 12 species from nine orders were examined. The 10 MDHV isolates all induced morphologically similar plaques in cell cultures closely resembling those of HN strain, a low pathogenic isolate of MDHV. Six of the 10 isolates, when inoculated into an experimental line of chickens highly susceptible to MD, caused only a minimal degree of histologic lesions without causing clinical MD, gross MD lesions, or deaths from MD. Natural hosts of MD are probably Galliformes, primarily affecting Gallus and less often other genera of Galliformes.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001717:Birds; D002642:Chick Embryo; D046508:Culture Techniques; D005347:Fibroblasts; D005455:Fluorescent Antibody Technique; D006564:Herpesviridae / Q000302:isolation & purification* / Q000472:pathogenicity; D007668:Kidney; D008380:Marek Disease / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D010948:Viral Plaque Assay
chemical_list: D000914:Antibodies, Viral