Depletion of suppressor T cells in syngeneic chimeric mice.
The present results suggest that some T-cell activities of syngeneic chimeric mice such as T-cells involved in the antibody response to SRBC and MLC reaction are intact. On the other hand, suppressor T-cells involved in the regulation of the immune response to PVP and enhancement of 3LL tumor growth, and cells mediating CML reaction are damaged.
D000818:Animals; D000917:Antibody Formation; D000941:Antigens; D002678:Chimera; D003601:Cytotoxicity Tests, Immunologic; D004912:Erythrocytes / Q000276:immunology; D006650:Histocompatibility Testing; D007165:Immunosuppression Therapy; D008213:Lymphocyte Activation; D051379:Mice; D009030:Mosaicism; D009374:Neoplasms, Experimental / Q000276:immunology; D011205:Povidone; D012756:Sheep / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
D000941:Antigens; D011205:Povidone