Passive immunological enhancement of muscle allografts in rats.
The effect of the passive administration of antiserum obtained from recipients immunized with antigens from H-1 + non-H-1 incompatible donors on muscle allograft survival in rats was studied. In transplantation across the non-H-1 antigenic barrier (H-1 compatible but non-H-1 incompatible) a satisfactory degree of immunological enhancement was achieved. Recovery of contractile properties of muscle allografts after different immunological treatments of the recipients was compared.
D000818:Animals; D006084:Graft Rejection; D007108:Immune Tolerance; D007112:Immunity, Maternally-Acquired; D007116:Immunization, Passive; D009119:Muscle Contraction; D009132:Muscles / Q000637:transplantation*; D051381:Rats; D011917:Rats, Inbred Lew; D014181:Transplantation Immunology; D014184:Transplantation, Homologous