title: Intercostal blocks with etidocaine. Preliminary report.
abstract: Although the results are few and should be considered as preliminary, the following conclusions may be drawn: 1. Etidocaine 0.5% and bupivacaine 0.5%, both with adrenaline (5 mug/ml), are comparable with regard to duration of sensory block. 2. Etidocaine 0.5% without adrenaline did not give the same duration of complete sensory block as when adrenaline was present. 3. Etidocaine 0.5% acts as a vasodilator at the site of injection. Adrenaline added to the solution counteracts the dilating effect. 4. Blood level studies of etidocaine do not at present show differences when 0.5% solution with or without adrenaline is used.
mesh_terms: D000083:Acetanilides / Q000031:analogs & derivatives*; D000328:Adult; D002045:Bupivacaine / Q000494:pharmacology; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004357:Drug Synergism; D004837:Epinephrine / Q000494:pharmacology; D005041:Etidocaine / Q000097:blood / Q000494:pharmacology; D006801:Humans; D007367:Intercostal Nerves / Q000098:blood supply / Q000187:drug effects*; D008875:Middle Aged; D009407:Nerve Block; D010149:Postoperative Pain / Q000188:drug therapy; D012039:Regional Blood Flow / Q000187:drug effects; D013900:Thoracic Nerves / Q000187:drug effects*; D013997:Time Factors
chemical_list: D000083:Acetanilides; D005041:Etidocaine; D002045:Bupivacaine; D004837:Epinephrine