The mutagenic effect of pesticides on Escherichia coli WP2 try.
Thirty pesticides commercially available in Hungary and three well-known chemical mutagens were applied to agar plate cultures of her+ and her- derivatives of Escherichia coli WP2 try- strain. After incubation, the plates were examined for a relative increase in reverse mutation number. N-Trichloro methylthio-1,2,3,6-tetrahydrophthalimide, dimethyl-3,2-dichlorovinyl-phosphate and N-trichloro methylthiophyhalamide proved to have definite mutagenic activity.
D000166:Acridines / Q000494:pharmacology; D002215:Captan / Q000494:pharmacology; D004260:DNA Repair; D004006:Dichlorvos / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects* / Q000378:metabolism; D005659:Fungicides, Industrial / Q000494:pharmacology; D008769:Methylnitronitrosoguanidine / Q000494:pharmacology; D009153:Mutagens; D009154:Mutation; D009605:Nitrosomethylurethane / Q000494:pharmacology; D010575:Pesticides / Q000494:pharmacology*; D014364:Tryptophan / Q000378:metabolism
D000166:Acridines; D005659:Fungicides, Industrial; D009153:Mutagens; D010575:Pesticides; D008769:Methylnitronitrosoguanidine; D009605:Nitrosomethylurethane; D004006:Dichlorvos; D014364:Tryptophan; D002215:Captan