Frequency of detection of Hemophilus influenzae type b capsular polysaccharide in infants and children with pneumonia.
Countercurrent immunoelectrophoresis was used to detect H. influenzae type b antigen in sera of 65 consecutive infants and children with clinical and radiographic evidence of pneumonia. Antigenemia was observed in only one patient who also had H. influenzae type b bacteremia. Blood cultures from four other children were positive for H. aphrophilus (one), Streptococcus pneumoniae (two), and an alpha-hemolytic Streptococcus (one). The frequency of pharyngeal colonization with H. influenzae type b was similar in children with or without pneumonia. If H. influenzae type b was the cause of pneumonitis in the children studied, it occurred without bacteremia or antigenemia.
D002648:Child; D002675:Child, Preschool; D003378:Counterimmunoelectrophoresis; D006192:Haemophilus Infections / Q000276:immunology* / Q000382:microbiology; D006193:Haemophilus influenzae / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D010614:Pharynx / Q000382:microbiology; D011014:Pneumonia / Q000276:immunology* / Q000382:microbiology; D011135:Polysaccharides, Bacterial / Q000032:analysis*
D011135:Polysaccharides, Bacterial