Pathophysiology of endolymphatic hydrops.
Endolymphatic hydrops of the nonprogressive type occurs in response to a single traumatic or toxic insult of limited duration and although it may result in permanent deficits in sensorineural function, there is total subsidence of vestibular symptoms. Endolymphatic hydrops of the progressive type, on the other hand, appears to be the result of permanent impairment of endolymph resorption and is caused principally by disorders of the endolymphatic sac. It occurs in Menière's disease, syphilitic labyrinthitis and the delayed hydrops syndrome. In addition to deafness of varying extent, it is characterized by episodic vertigo and sometimes by Hennebert's sign. Histological studies suggest that the acute vertiginous episodes are caused by potassium intoxication following ruptures of the membranous labyrinth and that Hennerbert's sign is caused by vestibular fibrosis.
D000368:Aged; D000818:Animals; D002415:Cats; D003051:Cochlea; D003638:Deafness / Q000209:etiology; D004487:Edema / Q000209:etiology*; D004710:Endolymph; D005260:Female; D006801:Humans; D007759:Labyrinth Diseases / Q000150:complications / Q000209:etiology*; D007761:Labyrinthine Fluids; D008297:Male; D008575:Meniere Disease / Q000209:etiology; D008875:Middle Aged; D009759:Nystagmus, Pathologic / Q000209:etiology; D011188:Potassium / Q000506:poisoning; D012422:Rupture, Spontaneous / Q000150:complications; D014717:Vertigo / Q000209:etiology; D014722:Vestibule, Labyrinth
D011188:Potassium