The in vitro and in vivo effects of carrageenin on humoral and cellular factors of natural resistance.
The inhibitory effect of carrageenin, a sulfated algal polygalactose, on humoral factors of natural resistance is discussed. In dependence on dose and time, the influence of non-specific and specific bacteriolysis, on the in vitro and in vivo opsonic activity and on the course of infection was studied.
D000818:Animals; D000907:Antibodies, Bacterial; D000917:Antibody Formation / Q000187:drug effects; D001433:Bacteriolysis; D001770:Blood Bactericidal Activity / Q000187:drug effects*; D002351:Carrageenan / Q000494:pharmacology* / Q000633:toxicity; D003169:Complement Inactivator Proteins; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000276:immunology; D006168:Guinea Pigs; D007106:Immune Sera; D007166:Immunosuppressive Agents; D008264:Macrophages / Q000276:immunology; D051379:Mice; D009895:Opsonin Proteins; D010587:Phagocytosis / Q000187:drug effects*; D011817:Rabbits; D012481:Salmonella Infections, Animal / Q000276:immunology; D013997:Time Factors
D000907:Antibodies, Bacterial; D003169:Complement Inactivator Proteins; D007106:Immune Sera; D007166:Immunosuppressive Agents; D009895:Opsonin Proteins; D002351:Carrageenan