Blockade of renin release by lanthanum.
1. The effects of lanthanum on renin release and renal vasoconstriction were studied in the isolated perfused rat kidney. 2. Lanthanum reduced noradrenaline-induced renal vasoconstriction. 3. Lanthanum prevented isoprenaline-induced and glucagon-induced stimulation of renin secretion.
D000818:Animals; D003864:Depression, Chemical; D005934:Glucagon / Q000037:antagonists & inhibitors; D066298:In Vitro Techniques; D007545:Isoproterenol / Q000037:antagonists & inhibitors; D007668:Kidney / Q000098:blood supply; D007811:Lanthanum / Q000494:pharmacology*; D009638:Norepinephrine / Q000037:antagonists & inhibitors; D010477:Perfusion; D051381:Rats; D012083:Renin / Q000378:metabolism*; D014661:Vasoconstriction / Q000187:drug effects*
D007811:Lanthanum; D005934:Glucagon; D012083:Renin; D007545:Isoproterenol; D009638:Norepinephrine