[Effect of thrombin on chemoreceptors of the frog carotid labyrinth].
The frog's electrical activity of the carotid body chemoreceptors reacting to thrombin was studied. The chemoreceptor response was estimated by means of afferent impulsation in the n. glossopharingeus. The afferent impulsation frequency increases to a certain extent in proportion to the irritant concentration; too high a thrombin concentration is able to suppress the chemoreceptor activity. The direct dependence between the receptor response and the effector reaction diminishing the blood coagulation, was established. The receptors adapt slowly, their discharge is of an irregular character.
D000818:Animals; D001777:Blood Coagulation; D002344:Carotid Body / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004594:Electrophysiology; D005930:Glossopharyngeal Nerve / Q000502:physiology; D011896:Rana temporaria; D013917:Thrombin / Q000494:pharmacology*; D013925:Thromboplastin / Q000494:pharmacology
D013925:Thromboplastin; D013917:Thrombin
O deĭstvii trombina na khemoretseptory karotidnogo labirinta liagushki