A case of unusual SLE related syndrome characterized by erythema multiforme, angioneurotic edema, marked hypocomplementemia, and Clq precipitins of the low molecular weight type.
Our patient and those of Agnello et al. had identical clinical symptoms such as erythema multiforme, arthralgias and angioneurotic edema and both differed from systemic lupus erthematosus in several important points, i.e., in spite of marked hypocomplementemia the nephropathy is not prominent and it needs high-dose steroids to eliminate the clinical and serological abnormalities. In addition to the features reported by Agnello et al. we found increased viral antibody titers in our patient's sera.
D000328:Adult; D000799:Angioedema / Q000276:immunology*; D000974:Antibodies, Antinuclear / Q000032:analysis; D003172:Complement C1 / Q000032:analysis*; D003165:Complement System Proteins / Q000032:analysis* / Q000172:deficiency*; D004892:Erythema Multiforme / Q000276:immunology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D008970:Molecular Weight; D011234:Precipitins / Q000032:analysis*; D013577:Syndrome
D000974:Antibodies, Antinuclear; D003172:Complement C1; D011234:Precipitins; D003165:Complement System Proteins