[The influence of riboflavin on vitreous homogenate (author's transl)].
Sunlight causes a decrease of viscosity of a mixture of riboflavin and ox vitreous homogenate while without riboflavin no reaction can be observed. The mechanism of this reaction is not yet clarified. It is possible that the reaction is closely related with the degradation of the viscosity of a hyaluronic acid solution by ascorbic acid cause of the production of H2O2 in both reactions. As an other mechanism the transfer of light energy on hyaluronic acid by riboflavin can be assumed.
D000818:Animals; D001205:Ascorbic Acid; D002417:Cattle; D002474:Cell-Free System; D006820:Hyaluronic Acid; D006861:Hydrogen Peroxide; D008027:Light; D012256:Riboflavin / Q000494:pharmacology*; D014783:Viscosity; D014822:Vitreous Body / Q000187:drug effects*
D006820:Hyaluronic Acid; D006861:Hydrogen Peroxide; D001205:Ascorbic Acid; D012256:Riboflavin
Der Eingluss von Riboflavin auf Glaskörperhomogenat