Succinic dehydrogenase as a measure of tissue viability in the cadaver kidney. Influence of perfusing solutions.
Succinic dehydrogenase (SDHG) has been studied in the rabbit cadaver kidney. Increasing warm ischemia time decreases the ability of the organ to utilize oxygen and therefore lowers its SDHG activity. The addition of perfusing solutions further decreases the SDHG activity; saline has a more adverse affect than either Perfudex or albumin.
D000418:Albumins / Q000009:adverse effects; D000818:Animals; D002102:Cadaver; D007511:Ischemia / Q000201:enzymology; D007668:Kidney / Q000098:blood supply / Q000201:enzymology; D016030:Kidney Transplantation; D009926:Organ Preservation; D010477:Perfusion; D011817:Rabbits; D012965:Sodium Chloride / Q000009:adverse effects; D013385:Succinate Dehydrogenase / Q000378:metabolism*; D014021:Tissue Preservation
D000418:Albumins; D012965:Sodium Chloride; D013385:Succinate Dehydrogenase