The outcome of dothiepin treatment in 1,900 depressed patients.
One thousand, nine hundred and sixty-five depressed patients took part in a multicentre study of dothiepin hydrochloride, which involved 392 doctors. The results indicated that a large percentage of patients improved as measured by all the assessments and no serious or adverse effects were encountered. A good correlation was seen between the global scale and the Rockliff depression scale; and also between the final mean Rockliff score and the number of patients stopping therapy due to recovery, and continuing treatment until recovery, at the final assessment.
D000293:Adolescent; D000328:Adult; D001007:Anxiety; D002986:Clinical Trials as Topic; D003863:Depression / Q000188:drug therapy*; D003988:Dibenzothiepins / Q000627:therapeutic use*; D004308:Dothiepin / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales
D003988:Dibenzothiepins; D004308:Dothiepin