Adult toxoplasmosis presenting as polymyositis and cerebellar ataxia.
A patient with toxoplasmosis had cerebellar, spinal cord, nerve root, and skeletal muscle symptoms. Toxoplasma gondii was isolated from skeletal muscle, and toxoplasma antibody titers were persistently elevated. The disease has been recurrent during a 3-year period with only temporary response to specific antimicrobial therapy.
D000941:Antigens; D001706:Biopsy; D002524:Cerebellar Ataxia / Q000209:etiology*; D003168:Complement Fixation Tests; D003402:Creatine Kinase / Q000097:blood; D006048:Gold Colloid, Radioactive; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D008751:Methylene Blue; D008875:Middle Aged; D008934:Mitogens / Q000494:pharmacology; D009132:Muscles / Q000473:pathology; D009220:Myositis / Q000209:etiology*; D011739:Pyrimethamine / Q000627:therapeutic use; D012008:Recurrence; D012698:Serologic Tests; D013411:Sulfadiazine / Q000627:therapeutic use; D014123:Toxoplasmosis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology
D000941:Antigens; D006048:Gold Colloid, Radioactive; D008934:Mitogens; D013411:Sulfadiazine; D003402:Creatine Kinase; D002955:Leucovorin; D008751:Methylene Blue; D011739:Pyrimethamine