Lysosomal acid hydrolases in human lymphocyte subpopulations.
Acid phosphatase and beta-glucuronidase activities have been determined cytochemically in T, B and null lymphocytes as part of an effort to charaterize the human haemopoietic stem cell. A combination of weak acid phosphatase activity and strong beta glucuronidase staining, in the form of a single large granule, has been shown to be specific for T cells. On the basis of this approach alone, non-T cells could not be further subclassified. Further cytochemical evaluation is being explored.
D000135:Acid Phosphatase / Q000097:blood; D001402:B-Lymphocytes; D001772:Blood Cell Count; D002469:Cell Separation; D005966:Glucuronidase / Q000097:blood; D006801:Humans; D007104:Immune Adherence Reaction; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000201:enzymology*; D008247:Lysosomes / Q000201:enzymology*; D009000:Monocytes; D013601:T-Lymphocytes
D000135:Acid Phosphatase; D005966:Glucuronidase