Homolanthionine in fungi: accumulation in the methionine-requiring mutants of Aspergillus nidulans.
Homolanthionine, a higher homologue of cystathionine, was found to accumulate in the mutants of Aspergillus nidulan impaired in the synthesis of methionine from homocysteine. The additional introduction of mutation resulting in a block at cystathionine gamma-synthase but not at cystathionine beta-synthase abolishes accumulation of both homolanthionine and cystathionine. This suggests a possible participation of cystathionine gamma-synthase in homolanthionine synthesis.
D001233:Aspergillus nidulans / Q000378:metabolism*; D003540:Cystathionine / Q000031:analogs & derivatives* / Q000378:metabolism; D008715:Methionine / Q000096:biosynthesis*; D009154:Mutation
D003540:Cystathionine; D008715:Methionine