title: [Effects of (--)delta-9-trans-tetrahydrocannabinol (delta-9-THC) on tests of psychoticism. A study of Eysenck's drug postulate on the effects of hallucinogens in relation to psychoticism (author's transl)].
abstract: In a double-blind study on 36 volunteers the effects of 250 mug/kg (--)delta-9-trans-tetrahydrocannabinol p.o. on objective and performance tests measuring psychoticism according to Eysenck were assessed. The hypothesis was tested that subjects treated with delta-9-THC differ from those receiving placebo in the same way as endogenous psychotics differ from normals. Confirmation was obtained in only 5 out of 19 variables. Four of these 5 variables may be considered as tests of concentration.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D002188:Cannabis / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D013759:Dronabinol / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D008722:Methods; D010552:Personality Assessment; D010919:Placebos; D011581:Psychological Tests; D011618:Psychotic Disorders / Q000503:physiopathology*
chemical_list: D010919:Placebos; D013759:Dronabinol
vernacular_title: Effekte von (--)delta-9-trans-Tetrahydrocannabinol (delta-9-THC) auf Psychotizismus-Tests. Eine Untersuchung des Eysenckschen Drogenpostulats über Beziehungen zwischen Halluzinogenwirkung und Psychotizismus