Interference of anti-allotype antisera with antigen-antibody binding.
Rabbit anti-b4 antisera are capable of inhibiting the antigen-binding ability of antibodies carrying b4 allotype. The data support the hypothesis of the localization of at least one b group allotypic determinant in the V region.
D000645:Ammonium Sulfate; D000818:Animals; D000906:Antibodies; D000907:Antibodies, Bacterial; D000937:Antigen-Antibody Reactions; D001666:Binding Sites, Antibody; D004140:Dinitrophenols / Q000276:immunology; D004926:Escherichia coli / Q000201:enzymology; D005696:Galactosidases; D007106:Immune Sera; D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D007519:Isoantigens; D011233:Precipitin Tests; D011511:Proteus / Q000276:immunology; D011817:Rabbits / Q000276:immunology; D012710:Serum Albumin, Bovine; D012711:Serum Albumin, Radio-Iodinated
D000906:Antibodies; D000907:Antibodies, Bacterial; D004140:Dinitrophenols; D007106:Immune Sera; D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D007519:Isoantigens; D012711:Serum Albumin, Radio-Iodinated; D012710:Serum Albumin, Bovine; D005696:Galactosidases; D000645:Ammonium Sulfate