Removal of leukocytes from whole blood and erythrocyte suspensions by filtration through cotton wool. V. Results after transfusion of 1,820 units of filtered erythrocytes.
1,820 units of leukocyte- and platelet-poor erythrocyte suspensions were prepared by filtration through cotton wool. On the average more than 98% of the leukocytes and 90-95% of the platelets could be removed. The red cell recovery was 96%. 97% of the units given to polytransfused patients did not cause febrile reactions. Serological follow-up of future transplantation recipients indicated that the immunization may be avoided by using erythrocyte suspensions of fresh, filtered blood.
D000906:Antibodies / Q000032:analysis; D001792:Blood Platelets; D001793:Blood Preservation; D001803:Blood Transfusion; D002469:Cell Separation / Q000379:methods*; D003601:Cytotoxicity Tests, Immunologic; D004912:Erythrocytes; D005334:Fever / Q000517:prevention & control; D005374:Filtration; D003368:Gossypium; D006649:Histocompatibility Antigens; D007114:Immunization; D007962:Leukocytes; D008233:Lymphotoxin-alpha / Q000032:analysis
D000906:Antibodies; D006649:Histocompatibility Antigens; D008233:Lymphotoxin-alpha