[A peculiarity in the humoral immunity of BALB/C mice with Rauscher leukemia].
There proved to be an increase in B-lymphocyte count (associated with increased synthesis of nonspecific immunoglobulins) in BALB/C mice highly sensitive to Rausher virus, after the administration of a relatively low dose of the virus. After the administration of the virus in combination with complete Freund's adjuvant in the spleen of mice, at the early periods of development of the disease, there were present normal cells synthesizing antibodies against the surface antigen of Rausher leukemia and leukemic cells with blocking antibodies adsorbed on their surface.
D000818:Animals; D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology; D005620:Freund's Adjuvant; D007942:Leukemia, Experimental / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D011925:Rauscher Virus; D013154:Spleen / Q000276:immunology
D005620:Freund's Adjuvant
Svoeobrazie gumoral'nogo immuniteta u mysheĭ BALB/C s leĭkozom Raushera