title: Tetracycline-sensitive mutants of the F-like R factors R100 and R100-1.
abstract: The majority of tetracycline-sensitive (Tets) mutants of R100 and R100-1 are multisite (deletion) mutants. About 50% of these are also transfer-deficient, indicating that the Tetr locus is closely linked to the transfer genes. Tet(s) mutants with single-site lesions are also described.
mesh_terms: D002872:Chromosome Deletion; D002876:Chromosomes, Bacterial; D003227:Conjugation, Genetic; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000502:physiology; D005144:F Factor; D009154:Mutation; D011815:R Factors; D013752:Tetracycline / Q000494:pharmacology*
chemical_list: D013752:Tetracycline