title: Treatment of children with perennial rhinitis with brompheniraminemaleate and phenylpropanolaminehydrochloride (lunerin mite)
abstract: The effect of a combined pediatric preparation of brompheniramine maleate and phenylpropanolaminehydrochloride (Lunerin mite) was studied in 17 children (aged 4-14 years) with allergic rhinitis. A double-blind cross-over technique was used, and a score system was used for evaluation of symptoms and signs. The results show that the drug had a good effect with statistical differences on the 1 per cent level between the active preparation and the placebo. The effect was less pronounced in children aged more than 10 years, for whom a higher dose of the drug is recommended. The frequency of side-effects was negligible.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001977:Brompheniramine / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004347:Drug Interactions; D004391:Dust; D005260:Female; D006801:Humans; D008297:Male; D010665:Phenylpropanolamine / Q000627:therapeutic use*; D010919:Placebos; D011725:Pyridines / Q000627:therapeutic use*; D012220:Rhinitis / Q000188:drug therapy*
chemical_list: D004391:Dust; D010919:Placebos; D011725:Pyridines; D010665:Phenylpropanolamine; D001977:Brompheniramine