title: Specificity of bovine thrombin and reptilase for mammalian plasmas.
abstract: The effect of bovine thrombin and reptilase was investigated on plasmas of ten species of five vertebrate classes. It was established that both enzymes have an expressed specificity for mammalian plasmas, however, their narrower species specificity is different. These comparative coagulation studies, their significance in the laboratory examination also contribute to the analysis of evolution of clotting factors.
mesh_terms: D000818:Animals; D012103:Batroxobin / Q000494:pharmacology*; D001779:Blood Coagulation Factors / Q000032:analysis; D001780:Blood Coagulation Tests; D002417:Cattle; D002645:Chickens; D003530:Cyprinidae; D006168:Guinea Pigs; D006801:Humans; D008322:Mammals; D010447:Peptide Hydrolases / Q000494:pharmacology*; D011893:Rana esculenta; D051381:Rats; D012589:Sciuridae; D013045:Species Specificity; D013917:Thrombin / Q000494:pharmacology*; D014426:Turtles
chemical_list: D001779:Blood Coagulation Factors; D010447:Peptide Hydrolases; D012103:Batroxobin; D013917:Thrombin