Production of homocytotropic antibody against acid extracts isolated from group A streptococcal cell walls in intact and adrenalectomized rats.
Intact and adrenalectomized rats of male Sprague-Dawley were injected with acid-extracted materials isolated from group A streptococcal cell walls using aluminum gel as an adjuvant. We have clearly demonstrated the production of homocytotropic antibodies against this antigens in rats. However, the homocytotropic antibody titers in adrenalectomized rats were much higher than those in intact rats.
D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D000942:Antigens, Bacterial / Q000008:administration & dosage; D002473:Cell Wall / Q000276:immunology*; D006386:Hemagglutination Tests; D007274:Injections, Intraperitoneal; D008297:Male; D010323:Passive Cutaneous Anaphylaxis; D051381:Rats / Q000276:immunology*; D013297:Streptococcus pyogenes / Q000276:immunology*; D013997:Time Factors
D000942:Antigens, Bacterial