title: Concurrence of ulcerative colitis and chronic acitve hepatitis, Clinical courses and results of colectomy.
abstract: Seven patients with coexisting chronic active hepatitis and ulcerative colitis are reviewed. The activity of the two diseases varied independently. Proctocolectomy was necessitated in 6 patients and was followed by disappearance or decreased in titres of smooth muscle and antinuclear autoantibodies and immunoglobulins and, in one patient, by a rapid normalization of markedly elevated transaminases. Although the series are small, we feel that our data suggest that proctocolectomy for severe ulcerative colitis may have some beneficial effect on a coexisting chronic active hepatitis.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000906:Antibodies / Q000032:analysis; D000974:Antibodies, Antinuclear / Q000032:analysis; D002648:Child; D002908:Chronic Disease; D003082:Colectomy; D003093:Colitis, Ulcerative / Q000209:etiology* / Q000276:immunology / Q000601:surgery; D005260:Female; D006505:Hepatitis / Q000150:complications* / Q000276:immunology / Q000601:surgery; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D009130:Muscle, Smooth / Q000276:immunology
chemical_list: D000906:Antibodies; D000974:Antibodies, Antinuclear; D007136:Immunoglobulins