title: Oestrogen therapy and serum cortisol in carcinoma of the prostate.
abstract: Patients with prostatic cancer, receiving oestrogen therapy were found to have elevated serum cortisol levels and lymphopenia. Oestrogens are known to have a profound effect on the immune system; the possibility that this effect is mediated through the adrenal cortex is discussed. The significance of these findings, however, remains to be determined.
mesh_terms: D000368:Aged; D002986:Clinical Trials as Topic; D004967:Estrogens / Q000627:therapeutic use*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D007111:Immunity, Cellular / Q000187:drug effects; D007958:Leukocyte Count; D008214:Lymphocytes; D008231:Lymphopenia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000097:blood / Q000188:drug therapy*
chemical_list: D004967:Estrogens; D006854:Hydrocortisone