title: [Conformations and interatomic distances in polymorphs of sulfanilamide].
abstract: By CNDO (Complete Neglect of Differential Overlap) molecular orbital method, interatomic distances and XYZ cartesian corrdinates were calculated in five polymorphs (monohydrated, alpha, two beta, and gamma) of sulfanilamide. Interatomic distances thus obtained are very close to those originally presented by Bells & Roblin and support the mechanism of action postulated long algo for sulfa drugs as being competitive antagonism with p-aminobenzoic acid.
mesh_terms: D010129:4-Aminobenzoic Acid / Q000037:antagonists & inhibitors; D008968:Molecular Conformation; D013424:Sulfanilamides / Q000037:antagonists & inhibitors
chemical_list: D013424:Sulfanilamides; D010129:4-Aminobenzoic Acid
vernacular_title: Conformações e distâncias interatômicas em polimorfos da sulfanilamida.