Pericarditis, pleural effusion, and pneumonitis with transient mitochondrial antibodies.
Four women with fever, arthromyalgias, pericarditis, pleural effusion, high erythrocyte sedimentation rates, and lymphopenia had mitochondrial antibodies in the serum in the absence of antinuclear antibody. Their illness lasted 5-12 weeks and the antibody test results became negative on remission. Absence of specific bacteriological findings, normal antistreptolysin O titres, resistance to antibiotics, and good response to steroids suggested that these cases represented a milder and less persistent form of the syndrome resembling systemic lupus erythematosus described by German authors.
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D001799:Blood Sedimentation; D003937:Diagnosis, Differential; D004351:Drug Resistance; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis; D008928:Mitochondria / Q000276:immunology*; D010493:Pericarditis / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D010996:Pleural Effusion / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D011014:Pneumonia / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D011241:Prednisone / Q000627:therapeutic use; D012459:Salicylates / Q000627:therapeutic use
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D012459:Salicylates; D011241:Prednisone