Mutagenicity of sodium hypochlorite for Salmonella typhimurium.
Sodium hypochlorite, a standard household item, induces base-substitution mutations in Salmonella typhimurium. Because of its potent bactericidal effect the mutagenicity of hypochlorite could best be demonstrated by short-term exposure to this chemical followed by the addition of ascorbic acid to decompose the hypochlorite.
D001205:Ascorbic Acid / Q000494:pharmacology; D001483:Base Sequence / Q000187:drug effects; D004269:DNA, Bacterial; D009153:Mutagens / Q000494:pharmacology*; D009154:Mutation; D012486:Salmonella typhimurium / Q000187:drug effects*; D012973:Sodium Hypochlorite / Q000494:pharmacology*; D013997:Time Factors
D004269:DNA, Bacterial; D009153:Mutagens; D012973:Sodium Hypochlorite; D001205:Ascorbic Acid