title: Cytotoxicity of normal rabbit serum for chicken lymphoid cells. I. Localization of the activity.
abstract: Normal rabbit sera were found to be highly cytotoxic for chicken thymus cells. When the sera were fractionated on Sephadex G-200, the natural cytotoixc activity resided exclusively in the first peak. It was found to be complement-dependent and heat stable at 56 degrees. On the other hand, in the serum of immunized animals the specific cytotoxic activity appeared in the second peak.
mesh_terms: D000818:Animals; D002645:Chickens; D002845:Chromatography; D003601:Cytotoxicity Tests, Immunologic; D007106:Immune Sera; D011817:Rabbits; D013045:Species Specificity; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D007106:Immune Sera