Posterior fossa tumors with pathological laughter.
Of two patients with posterior fossa tumor and pathological laughter, one had extrinsic compression of the brain stem; the other had an intrinsic brain-stem lesion. Surgical removal of the epidermoid from the cerebellopontine angle cured the laughter. The euphoria of multiple sclerosis with paroxysmal laughter and a feeling of joy is to be differentiated from cases in which pathological laughter is a presenting complaint.
D000328:Adult; D001932:Brain Neoplasms / Q000150:complications*; D001933:Brain Stem; D002530:Cerebellopontine Angle / Q000601:surgery; D003388:Cranial Fossa, Posterior; D005260:Female; D005910:Glioma / Q000150:complications*; D006801:Humans; D007845:Laughter; D008297:Male; D012886:Skull; D012888:Skull Neoplasms / Q000150:complications* / Q000601:surgery