Morphology and time course of experimental listeriosis in nude mice.
Experimental listeriosis in phenotypically normal (nu/+) euthymic NMRI mice has a characteristic morphology and short-term course. In contrast, listeric infection in congenitally dysthymic nude (nu/nu)  mice does not proceed in clear-cut phases, develops more slowly, displays a chronic tendency from the beginning, and shows a considerably different morphology. The inability of nude mice to effectively control and terminate infection by Listeria monocytogenes obviously results from the lack of T lymphocytes.
D000818:Animals; D006099:Granuloma / Q000473:pathology; D008088:Listeriosis / Q000276:immunology* / Q000473:pathology; D008099:Liver / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D051379:Mice; D008819:Mice, Nude / Q000382:microbiology*; D013154:Spleen / Q000473:pathology; D013601:T-Lymphocytes / Q000276:immunology; D013997:Time Factors