Immunodeficiency syndromes with otorhinolaryngological manifestations.
Among patients with recurrent, protracted or chronic infections of the respiratory tract involving the middle ear, 18 were found to have immunodeficiencies. In 10 of the patients, deficiency of immunoglobulins belonging to the IgG, IgA and IgM classes was found. Seven patients had an isolated IgA deficiency. One patient had a combined immunodeficiency with defects of the T-cell system and the B-cell system. One patient had an isolated T-cell deficiency.
D000293:Adolescent; D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications*; D001402:B-Lymphocytes / Q000276:immunology; D002648:Child; D002908:Chronic Disease; D005260:Female; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000150:complications* / Q000276:immunology; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010033:Otitis Media / Q000150:complications / Q000276:immunology / Q000382:microbiology; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000150:complications* / Q000276:immunology / Q000382:microbiology; D013601:T-Lymphocytes / Q000276:immunology
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M