title: [The clinical problem of hereditary hemorrhagic diseases developing prolonged bleeding time].
abstract: Thirty-two patients with hereditary hemorrhagic diseases and a platelet functional abnormality were set apart from our group of patients with hereditary hemorrhagic diseases, and their symptoms, signs and hematological examinations were collected; the initial events and the age of the patients when they were obsserved, the main hemorrhagic manifestations during their clinical course, the clinical severity of the disorders, the survival of the patients and the laboratory test for hemostasis useful to make the diagnosis, were evaluated. In reference to bleeding time, thirty patients had abnormal bleeding time, but the other two had normal bleeding time.
mesh_terms: D000293:Adolescent; D000328:Adult; D001778:Blood Coagulation Disorders / Q000097:blood / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D001791:Blood Platelet Disorders / Q000175:diagnosis; D002648:Child; D002675:Child, Preschool; D003241:Consanguinity; D003937:Diagnosis, Differential; D005169:Factor VIII / Q000032:analysis; D005260:Female; D006487:Hemostasis; D006801:Humans; D008297:Male; D011379:Prognosis; D011696:Purpura, Thrombocytopenic / Q000175:diagnosis; D014842:von Willebrand Diseases / Q000175:diagnosis
chemical_list: D005169:Factor VIII
vernacular_title: El problema clínico de las enfermedades hemorrágicas hereditarias que evolucionan con tiempo de sangrado prolongado