A study on the effect of certain compound during elimination of plasmids in Escherichia coli.
Of several chemicals tested on the elimination of plasmids from Escherichia coli K-12, the compound designated ICR-170 was most effective, applied at 100 mu g/ml, the effect being comparable to that of acriflavin. It had no effect on the elimination of the R1 plasmid from Escherichia coli JC 5455.
D000166:Acridines / Q000494:pharmacology*; D002470:Cell Survival; D055598:Chemical Phenomena; D002621:Chemistry; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D005111:Extrachromosomal Inheritance / Q000187:drug effects*; D007785:Lactose / Q000378:metabolism*; D008826:Microbial Sensitivity Tests; D009154:Mutation; D009285:Naphthoquinones / Q000494:pharmacology*; D009588:Nitrogen Mustard Compounds / Q000494:pharmacology*; D012723:Sex
D000166:Acridines; D009285:Naphthoquinones; D009588:Nitrogen Mustard Compounds; D007785:Lactose