[Aggregate-hemagglutination test for anti-erythrocyte antibodies].
A new test for detection of antierythrocyte antibodies is described; one of its variants is three orders of magnitude more sensitive than the classic Coombs test. The proposed procedures are based on the agglutination of the red blood cells following addition of test-erythrocytes coated with the aggregated proteins of an antiglobulin serum. Results of application of the technique for diagnosis of the autoimmune hemolytic anemia showed its high specificity and the absence of prozone phenomenon.
D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis*; D000888:Antibodies, Anti-Idiotypic; D003298:Coombs Test; D004912:Erythrocytes / Q000276:immunology*; D005069:Evaluation Studies as Topic; D006386:Hemagglutination Tests / Q000379:methods*; D006801:Humans; D007518:Isoantibodies / Q000032:analysis*
D000888:Antibodies, Anti-Idiotypic; D007518:Isoantibodies
Agregat-gemaggliutinatsionnaia proba na antiéritrotsitarnye antitela