One hundred twin pairs patch tested with primary irritants.
The cutaneous sensitivity to benzalkonium chloride, sodium lauryl sulphate and potash soap was determined in 54 monozygotic and 46 dizygotic twin pairs. Comparing the intra-pair reaction strength a higher degree of concordance was found among monozygotic than among dizygotic twins, and even more so when monozygotic twins were compared with matched controls.
D000293:Adolescent; D000328:Adult; D001548:Benzalkonium Compounds; D002986:Clinical Trials as Topic; D003876:Dermatitis, Atopic / Q000235:genetics; D004200:Diseases in Twins / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007509:Irritants; D008297:Male; D010328:Patch Tests; D011247:Pregnancy; D012915:Soaps; D012967:Sodium Dodecyl Sulfate; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic
D001548:Benzalkonium Compounds; D007509:Irritants; D012915:Soaps; D012967:Sodium Dodecyl Sulfate