Autologous bone marrow transplantation.
Bone marrow cells can be aspirated from patients with malignant disorders, stored at low temperatures, and reinfused into the same patient at a later date. In the past, the results of this autologous bone marrow transplantation were equivocal. With the availability of better methods for cryopreservation and more accurate assays for the survival of hemopoietic progenitor cells, there has been a resurgence of interest in this procedure.
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D002470:Cell Survival; D003080:Cold Temperature; D003451:Cryoprotective Agents / Q000494:pharmacology; D003520:Cyclophosphamide / Q000494:pharmacology; D003864:Depression, Chemical; D005260:Female; D006412:Hematopoietic Stem Cells / Q000502:physiology; D006649:Histocompatibility Antigens; D006801:Humans; D007938:Leukemia / Q000601:surgery; D008297:Male; D014021:Tissue Preservation; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous
D003451:Cryoprotective Agents; D006649:Histocompatibility Antigens; D003520:Cyclophosphamide