[Relation of the immune response in rats to the state of the lysosomes and intensity of protein synthesis].
In stimulation of an immune response to salmonellae in rats by dibasol and methyluracil and its depression by chlorophos and an amine salt of 2,4-dichlorphenoacetic acid it was found that the intensity of the immune response depended more on the level of protein biosynthesis than on the state of lysosomes at the period preceding the immunization.
D015084:2,4-Dichlorophenoxyacetic Acid / Q000494:pharmacology; D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D000942:Antigens, Bacterial; D001562:Benzimidazoles / Q000494:pharmacology; D002250:Carbon Radioisotopes; D002463:Cell Membrane Permeability; D005998:Glycine; D007166:Immunosuppressive Agents / Q000494:pharmacology; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D008198:Lymph Nodes / Q000201:enzymology / Q000378:metabolism; D008247:Lysosomes / Q000502:physiology*; D010276:Parasympatholytics / Q000494:pharmacology; D014176:Protein Biosynthesis; D051381:Rats; D012477:Salmonella enteritidis / Q000276:immunology; D013154:Spleen / Q000201:enzymology / Q000378:metabolism; D013268:Stimulation, Chemical; D014236:Trichlorfon / Q000494:pharmacology; D014498:Uracil / Q000031:analogs & derivatives / Q000494:pharmacology
D000942:Antigens, Bacterial; D001562:Benzimidazoles; D002250:Carbon Radioisotopes; D007166:Immunosuppressive Agents; D010276:Parasympatholytics; D015084:2,4-Dichlorophenoxyacetic Acid; D014498:Uracil; D014236:Trichlorfon; D000135:Acid Phosphatase; D005998:Glycine
Zavisimost' immunnogo otveta u krys ot sostoianiia lizosom i intensivnosti biosinteza belka