[Hematopoietic stem cells and antiblastic drugs. II. Variations in the colony forming cells in vivo after administration of peptichemio].
Peptichemio, administered in a single LD50, dose, induces a significant reduction of mice bone marrow and spleen CFUs. The lesive action appears to be similar to that observed after a single dose of various antineoplastic agents. The effects of increasing doses of Peptichemio are also reported.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002999:Clone Cells / Q000187:drug effects; D003115:Colony-Stimulating Factors / Q000494:pharmacology; D005260:Female; D006412:Hematopoietic Stem Cells / Q000187:drug effects*; D051379:Mice; D009588:Nitrogen Mustard Compounds / Q000494:pharmacology*; D010440:Peptichemio / Q000008:administration & dosage / Q000494:pharmacology*
D003115:Colony-Stimulating Factors; D009588:Nitrogen Mustard Compounds; D010440:Peptichemio
Cellule staminali emopoietiche ed antiblastici. II. Variazioni delle cellule formatrici di colonie in vivo dopo somministrazione di peptichemio