title: Streptococcal cellulitis of the scrotum and penis with secondary skin gangrene.
abstract: Cellulitis of the scrotum and penis is caused, in the majority of instances, by a beta hemolytic streptococci without a discernible portal of entry. Clostridium, occasionally, will result in this disease as a manifestation of a perirectal abscess. In either instance, fluid accumulates rapidly in the closed space between Colles' and Buck's fascia, producing intense swelling of the scrotum. If this compartment is not immediately decompressed by linear incisions, devascularization of the scrotal and penile skin will often occur, resulting in gangrene. Immediate treatment of the bacterial infection with penicillin also is essential. If gangrene does develop, radical debridement of the necrotic tissue as well as a wide margin of adjacent inflamed skin must be undertaken. Continual monitoring of the microflora of the debrided would is essential for the selection of the appropriate antibiotic against any secondary intruders. Coverage of the granulating would is accomplished when the would bacterial count is below 10-5 per gram of tissue.
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000989:Antistreptolysin / Q000302:isolation & purification; D002176:Candida albicans / Q000302:isolation & purification / Q000472:pathogenicity; D002177:Candidiasis / Q000188:drug therapy; D002481:Cellulitis / Q000209:etiology*; D003646:Debridement; D005734:Gangrene / Q000209:etiology*; D005832:Genital Diseases, Male / Q000209:etiology; D006801:Humans; D007109:Immunity; D008297:Male; D008875:Middle Aged; D010409:Penile Diseases / Q000209:etiology*; D012611:Scrotum; D012871:Skin Diseases / Q000209:etiology*; D016038:Skin Transplantation; D013290:Streptococcal Infections / Q000150:complications* / Q000188:drug therapy; D014182:Transplantation, Autologous
chemical_list: D000900:Anti-Bacterial Agents; D000666:Amphotericin B; D000989:Antistreptolysin