title: New approaches to cancer chemotherapy with methotrexate.
mesh_terms: D000328:Adult; D000818:Animals; D001692:Biological Transport; D001853:Bone Marrow / Q000187:drug effects; D003404:Creatinine / Q000097:blood; D004273:DNA, Neoplasm / Q000096:biosynthesis; D004317:Doxorubicin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D007668:Kidney / Q000187:drug effects; D002955:Leucovorin / Q000008:administration & dosage* / Q000627:therapeutic use; D007939:Leukemia L1210 / Q000188:drug therapy; D008175:Lung Neoplasms / Q000517:prevention & control; D008727:Methotrexate / Q000008:administration & dosage* / Q000627:therapeutic use / Q000633:toxicity; D051379:Mice; D009362:Neoplasm Metastasis / Q000517:prevention & control; D009369:Neoplasms / Q000188:drug therapy*; D012516:Osteosarcoma / Q000188:drug therapy; D011687:Purines / Q000096:biosynthesis; D013936:Thymidine / Q000627:therapeutic use; D013942:Thymine Nucleotides / Q000096:biosynthesis
chemical_list: D004273:DNA, Neoplasm; D011687:Purines; D013942:Thymine Nucleotides; D004317:Doxorubicin; D003404:Creatinine; D002955:Leucovorin; D013936:Thymidine; D008727:Methotrexate