title: Late sodium current in the node of Ranvier.
abstract: Voltage clamp experiments carried out on nodes of Ranvier of myelinated fibres of Rana esculenta showed that a small fractoon of sodium channels fail to inactivate. Thus during long lasting depolarizing pulses there is a small Na-current superimposed on the leakage and potassium currents. This late Na-current appears more marked in sensory fibres than in motor ones.
mesh_terms: D000818:Animals; D004594:Electrophysiology; D008564:Membrane Potentials; D009413:Nerve Fibers, Myelinated / Q000502:physiology; D011188:Potassium; D011893:Rana esculenta; D011901:Ranvier's Nodes / Q000502:physiology*; D012964:Sodium; D013997:Time Factors
chemical_list: D012964:Sodium; D011188:Potassium