Hemorrhagic diathesis in a carrier of hemophilia B.
A carrier of hemophilia B was found to have an unusually low factor IX level of 13 per cent. Her history of previous bleeding and the hospital course following elective dental extractions were consistent with a mild hemorrhagic diathesis. The patient is a member of a rare kindred of hemophiliacs. The mean level of factor IX in 12 carriers in this kindred was 42 per cent, with a range of 13 to 100 per cent. This patient represents the sixth reported case in which a female carrier of factor IX deficiency was symptomatic.
D000328:Adult; D001803:Blood Transfusion; D005164:Factor IX / Q000032:analysis; D005260:Female; D006400:Hematocrit; D002836:Hemophilia B / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D006472:Oral Hemorrhage / Q000209:etiology* / Q000628:therapy; D010375:Pedigree; D010949:Plasma; D011300:Preoperative Care; D014081:Tooth Extraction; D014095:Tooth, Impacted / Q000601:surgery
D005164:Factor IX