Generalized mastocytosis in a foal, resembling urticaria pigmentosa of man.
A newborn foal with multiple, nodular, cutaneous lesions containing mast cells and with mast cell accumulations in bone marrow was observed for 1 year. Cutaneous nodules grew to several centimeters in size, ulcerated, and regressed. Only a few healed nodules remained when the foal was 1 year old. The disease was considered to be similar to urticaria pigmentosa of man.
D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D000917:Antibody Formation; D001219:Aspartate Aminotransferases / Q000097:blood; D001853:Bone Marrow / Q000473:pathology; D006084:Graft Rejection; D006734:Horse Diseases / Q000097:blood / Q000473:pathology; D006736:Horses; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008407:Mast Cells / Q000473:pathology*; D012867:Skin / Q000473:pathology; D016038:Skin Transplantation; D013154:Spleen / Q000473:pathology; D014184:Transplantation, Homologous; D014582:Urticaria Pigmentosa / Q000097:blood / Q000473:pathology / Q000662:veterinary*
D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase