title: Pulmonary emphysema and liver disease.  Occurrence in an alpha-antitrypsin-deficient adult.
abstract: An elderly woman manifested both pulmonary and hepatic disease secondary to alpha 1-antitrypsin deficiency.  The liver biopsy specimen showed the characteristic findings of this condition, most importantly, the presence of PAS-positive, diastase-resistant intracytoplasmic inclusions.
mesh_terms: D001706:Biopsy; D005260:Female; D006801:Humans; D006971:Hypersplenism / Q000209:etiology; D006975:Hypertension, Portal / Q000209:etiology; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000209:etiology* / Q000473:pathology; D008168:Lung / Q000473:pathology; D008875:Middle Aged; D011656:Pulmonary Emphysema / Q000209:etiology*; D013902:Radiography, Thoracic; D019896:alpha 1-Antitrypsin Deficiency