Intraocular reticulum-cell sarcoma: clinico-pathologic study of four cases and review of the literature.
Four patients with primary intraocular reticulum-cell sarcoma were presented. All of the patients were followed at the Wilmer Institute for periods of up to ten years. All had decreased visual acuity and a uveitis that was refractory to standard forms of therapy. In one case, the correct diagnosis was made clinically. At autopsy, two of the patients had systemic reticulum-cell sarcoma, a third had intracranial reticulum-cell sarcoma, and in a fourth case the disease process was confined to the eye. The literature is reviewed and the clinico-pathologic features of the total of 14 cases are analyzed. It is emphasized that a recalcitrant uveitis was present in almost all of the cases reported. Differential diagnosis and methods of diagnosis are discussed.
D000328:Adult; D000368:Aged; D001344:Autopsy; D002829:Choroid / Q000473:pathology; D003228:Conjunctiva / Q000473:pathology; D003937:Diagnosis, Differential; D005134:Eye Neoplasms / Q000175:diagnosis / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009900:Optic Nerve / Q000473:pathology; D012160:Retina / Q000473:pathology; D014602:Uvea / Q000473:pathology; D014605:Uveitis / Q000209:etiology; D014786:Vision Disorders / Q000209:etiology; D014792:Visual Acuity; D014822:Vitreous Body / Q000473:pathology