Cross-reactivity between human thymus and mouse lymphoid tissues, as revealed by rabbit antiserum against human brain.
Rabbit anti-human brain antisera were found cytotoxic for mouse thymus, lymph node, and spleen cells. Absorption with human thymus cells removed some of the cytotoxic antibodies. Cross-reactions were also detected among human brain and thymus and mouse brain, liver, and erythrocytes.
D000818:Animals; D000918:Antibody Specificity; D000961:Antilymphocyte Serum; D001921:Brain / Q000276:immunology*; D003429:Cross Reactions; D003601:Cytotoxicity Tests, Immunologic; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D008099:Liver / Q000276:immunology; D008198:Lymph Nodes / Q000276:immunology; D008221:Lymphoid Tissue / Q000276:immunology*; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D011817:Rabbits / Q000276:immunology; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology*
D000961:Antilymphocyte Serum