title: Absent vestibulo-ocular reflexes and acute supratentorial lesions.
abstract: Loss of vestibulo-ocular reflexes occurred in two patients with acute supratentorial lesions who received therapeutic doses of anticonvulsant drugs. There was no clinical or angiographic evidence of focal brain-stem damage. Absence of vestibulo-ocular reflexes is attributed to a combination of acute cerebral damage and anticonvulsant drugs. The loss of these reflexes in patients with acute cerebral lesions cannot be interpreted as evidence of irreversible brain-stem injury.
mesh_terms: D000208:Acute Disease; D000328:Adult; D000654:Amobarbital / Q000009:adverse effects; D000927:Anticonvulsants / Q000009:adverse effects; D001933:Brain Stem; D002536:Cerebral Arteries; D002648:Child; D003392:Cranial Sinuses; D004359:Drug Therapy, Combination; D005133:Eye Movements; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications* / Q000503:physiopathology; D002542:Intracranial Embolism and Thrombosis / Q000150:complications*; D008297:Male; D010634:Phenobarbital / Q000009:adverse effects; D010672:Phenytoin / Q000009:adverse effects; D012021:Reflex, Abnormal / Q000139:chemically induced / Q000209:etiology*; D013345:Subarachnoid Hemorrhage / Q000150:complications / Q000209:etiology; D014724:Vestibular Function Tests; D014722:Vestibule, Labyrinth / Q000503:physiopathology
chemical_list: D000927:Anticonvulsants; D010672:Phenytoin; D000654:Amobarbital; D010634:Phenobarbital