title: Use of biochemical profile in children's hospital: results of two controlled trials.
abstract: Two controlled trials of the use of a biochemical profile were conducted in a childern's hospital to see whether the profile led to diagnoses which would not otherwise [have been made and to see what effect it had on the number of extra  requests for pathololgical investigations and the length of stay in hospital]. Altogether 2816 children were examined and 13 new diagnoses made. There was a significant increases in the total number of pathorequests but the profile did not alter the length of stay in hospital. We conclude that the profile mad only a small contribtuion to the overall care of the pateints.
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood; D000740:Anemia / Q000175:diagnosis; D001219:Aspartate Aminotransferases; D001706:Biopsy; D001786:Blood Glucose; D001798:Blood Proteins; D002118:Calcium / Q000097:blood; D002245:Carbon Dioxide / Q000097:blood; D002648:Child; D002675:Child, Preschool; D019411:Clinical Laboratory Techniques; D002986:Clinical Trials as Topic; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006776:Hospitals, Pediatric; D006801:Humans; D006937:Hypercholesterolemia / Q000175:diagnosis; D006996:Hypocalcemia / Q000175:diagnosis; D007223:Infant; D007231:Infant, Newborn; D007902:Length of Stay; D008131:London; D008274:Magnesium / Q000097:blood; D008297:Male; D010758:Phosphorus / Q000097:blood; D011188:Potassium / Q000097:blood; D012279:Rickets / Q000175:diagnosis; D012964:Sodium / Q000097:blood; D014508:Urea / Q000097:blood
chemical_list: D001786:Blood Glucose; D001798:Blood Proteins; D006454:Hemoglobins; D002245:Carbon Dioxide; D010758:Phosphorus; D014508:Urea; D012964:Sodium; D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase; D008274:Magnesium; D011188:Potassium; D002118:Calcium