Arterial vasoconstrictor therapy for bleeding oesophageal varices.
Upper gastrointestinal bleeding in patients with hepatic cirrhosis carries considerable mortality. Difficulties are encountered both in determining the source of bleeding and in controlling blood loss. The techniques of selective visceral angiography not only supply diagnostic information, but can be used to administer selective intra-arterial vasoconstrictor therapy to control blood loss. We report our experience with 28 patients in whom angiography was performed with particular reference to six patients treated with selective vasoconstrictor therapy. Although the precise role of the technique is not yet established, early experience is most promising. We believe it will play an important role in a difficult group of patients in the future and may well supplant present methods of controlling bleeding.
D000328:Adult; D004932:Esophageal and Gastric Varices / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000000981:diagnostic imaging / Q000188:drug therapy; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008638:Mesenteric Arteries; D008875:Middle Aged; D011859:Radiography; D014667:Vasopressins / Q000008:administration & dosage* / Q000627:therapeutic use
D014667:Vasopressins