[The effect of acetyl-salicylic-acid and a pyrido-pyrimidine-derivate on the rejection of allotransplanted canine kidneys (author's transl)].
The effects of anti-thrombotic drugs-Acetyl-salicylic-acid and 2-Piperazinly-4-thiomorpholino-pyrido(3,2-d)-pyrimidin-sulfat-trihydrat-on rejection reactions of renal allografts in dogs have been studied. From the clinical point of view no effectiveness of the two drugs can be found, whereas the histological findings do clearly show diminished rejection reactions in the Acetylsalicylic-acid group.
D000818:Animals; D001241:Aspirin / Q000494:pharmacology*; D004285:Dogs; D006084:Graft Rejection / Q000187:drug effects*; D007668:Kidney / Q000473:pathology; D007672:Kidney Cortex / Q000473:pathology; D016030:Kidney Transplantation; D010973:Platelet Adhesiveness / Q000187:drug effects; D011743:Pyrimidines / Q000494:pharmacology*; D014184:Transplantation, Homologous
D011743:Pyrimidines; D001241:Aspirin
Wirkung von Acetylsalicylsäure und einum Pyrido-pyrimidin-Derivat auf die Abstobetaung allotransplantierter Nieren im Tierexperiment