Trichomonal vaginitis. A 24-hr regimen of nimorazole compared with a 7-day regimen of metronidazole.
A 24-hr regimen of nimorazole (1 g. orally at 12-hrly intervals for three doses) was compared with metronidazole (200 mg. three times daily for 7 days) in the treatment of trichomonal vaginitis. The two treatment schedules were given to alternate patients, pregnant women being excluded. One hundred cases were treated on each schedule; roughly one-fifth of the patients in each group defaulted. There were no observed failures with either schedule. The reasons for these exceptionally good results are discussed.
D000284:Administration, Oral; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use*; D009554:Nimorazole / Q000008:administration & dosage / Q000627:therapeutic use*; D009593:Nitroimidazoles / Q000627:therapeutic use*; D014247:Trichomonas Vaginitis / Q000188:drug therapy*
D009593:Nitroimidazoles; D008795:Metronidazole; D009554:Nimorazole