title: Bacteriophage Mu-1-induced permeability mutants in Escherichia coli K-12.
abstract: Apparent permeability mutations were produced in Escherichia coli K-12 by bacteriophage mu-1 mutagenesis. They are pleiotropic mutations showing sensitivity to a number of detergents and unrelated antibiotics, and presumably they affect cell wall or membrane biosynthesis. One of the mutations was genetically mapped at a site in or near the acrA and mtc loci at approximately 10.5 min on the Taylor and Trotter map (1972).
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002463:Cell Membrane Permeability; D002874:Chromosome Mapping; D002981:Clindamycin / Q000494:pharmacology; D003090:Coliphages / Q000254:growth & development*; D003227:Conjugation, Genetic; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000166:cytology* / Q000187:drug effects; D005144:F Factor; D008242:Lysogeny; D009154:Mutation; D013501:Surface-Active Agents / Q000494:pharmacology; D014161:Transduction, Genetic
chemical_list: D000900:Anti-Bacterial Agents; D013501:Surface-Active Agents; D002981:Clindamycin