The induction, persistence and loss of framycetin sulphate resistance in enteric E coli of pigs.
When framycetin sulphate was fed at prophylactic levels to pigs, resistance to this antibiotic was induced within days in the enteric E coli. The E coli of the gut did not become fully susceptible again until six to seven weeks after the anitbiotic was withdrawn from the diet.
D000284:Administration, Oral; D000821:Animal Feed; D000818:Animals; D003227:Conjugation, Genetic; D003470:Culture Media; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects*; D005111:Extrachromosomal Inheritance; D005601:Framycetin / Q000008:administration & dosage / Q000494:pharmacology*; D007422:Intestines / Q000382:microbiology*; D009268:Nalidixic Acid / Q000494:pharmacology; D012486:Salmonella typhimurium / Q000187:drug effects; D013431:Sulfates / Q000494:pharmacology; D013552:Swine / Q000382:microbiology*
D003470:Culture Media; D013431:Sulfates; D009268:Nalidixic Acid; D005601:Framycetin