Double-blind comparison of halcinonide and betamethasone valerate. Use with occlusive dressings in psoriasis treatment.
In a double-blind, paired-comparison study of the effectiveness of corticosteroid creams used under occlusion for the treatment of moderate to severe psoriasis, a new drug, halcinonide cream, was superior to betamethasone valerate cream, a steroid widely and effectively used for the treatment of psoriasis. This superiority was demonstrated in patients after both one and two weeks of treatment.
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001623:Betamethasone / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D008297:Male; D008875:Middle Aged; D009779:Occlusive Dressings; D009824:Ointments; D011282:Pregnenediones / Q000627:therapeutic use*; D011565:Psoriasis / Q000188:drug therapy*; D013258:Steroids, Chlorinated / Q000627:therapeutic use; D013259:Steroids, Fluorinated / Q000627:therapeutic use; D014631:Valerates / Q000008:administration & dosage / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D009824:Ointments; D011282:Pregnenediones; D013258:Steroids, Chlorinated; D013259:Steroids, Fluorinated; D014631:Valerates; D001623:Betamethasone