Tumor-associated antibodies in the serum of patients with uveal melanoma.
Antibodies reacting with autologous and allogeneic cytoplasmic antigens and with autologous surface membrane antigens of uveal melanoma cells were demonstrated in the serum of three patients with relatively small, histologically-proven malignant melanomas of the choroid. The significance of these findings and planned applications of these investigations with regard to diagnosis, prognosis, and therapy of patients with suspected or proven ocular melanomas are discussed.
D000368:Aged; D000912:Antibodies, Neoplasm / Q000032:analysis*; D000954:Antigens, Surface / Q000276:immunology; D002830:Choroid Neoplasms / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000276:immunology*; D008875:Middle Aged; D014604:Uveal Neoplasms / Q000276:immunology*
D000912:Antibodies, Neoplasm; D000954:Antigens, Surface