Malignant fibrous mesothelioma. Metastatic to brain and liver.
A malignant fibrous mesothelioma in a 52 year old white man arising from the left parietal pleura associated with lupus erythematosus with metastases to brain and liver is reported. Asbestos bodies were found in digested pulmonary tissue but none in the primary or metastatic lesions. Light microscopic and ultrastructural studies suggest that this tumor contains mesothelial or endothelial cells, some of which revealed fibroblastic features while others disclosed epitheloid characteristics.
D001194:Asbestos / Q000032:analysis; D001932:Brain Neoplasms / Q000032:analysis / Q000473:pathology*; D002530:Cerebellopontine Angle; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D005347:Fibroblasts / Q000648:ultrastructure; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D008654:Mesothelioma / Q000032:analysis / Q000473:pathology*; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000473:pathology*; D010997:Pleural Neoplasms / Q000032:analysis / Q000473:pathology*; D011149:Pons
D001194:Asbestos