Dynamics of nucleic acids and total proteins in thymus of Walker carcinosarcoma bearing rats.
Thymus responses in tumoral-bearing hosts can illustrate two moments of immunological crisis corresponding to the tumour intake and its metastazic spread. These data are in accord with Burnet's (3) hypothesis that cancer is due to the inability of immunological surveillance mechanisms to reject somatic cells bearing neoplastic mutation.
D000818:Animals; D000917:Antibody Formation; D002279:Carcinoma 256, Walker / Q000276:immunology*; D004273:DNA, Neoplasm / Q000276:immunology*; D007111:Immunity, Cellular; D008297:Male; D009368:Neoplasm Transplantation; D011506:Proteins / Q000276:immunology*; D012334:RNA, Neoplasm / Q000276:immunology*; D051381:Rats; D013601:T-Lymphocytes / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology*
D004273:DNA, Neoplasm; D011506:Proteins; D012334:RNA, Neoplasm