[Effect of thymocyte autotransplantation on postradiation regeneration of hematopoiesis].
Experiments were conducted on Wistar rats irradiated in a dose of 400 R; a study was made of the effect of thymocyte autotransplantation (4-10(8)--8-10(8)) on the restoration of cell number of the bone marrow and the spleen. There was revealed a significant stimulating effect of autotransplantation of thymocytes on the erythroid and granulocytic series in the bone marrow and on the lymphoid one in the spleen during the restoration (the 5 th-- 7 th days) after the irradiation. Irradiation of the thymocyte suspension with gamma-rays in a dose of 10 000 R failed to prevent the effect of autotransplantation on the bone marrow, but decreased its stimulating effect. A conclusion was drawn on the interaction of the administered thymocytes with the stem hemopoietic cell.
D000818:Animals; D003037:Cobalt Radioisotopes; D005720:Gamma Rays; D006410:Hematopoiesis; D008297:Male; D011833:Radiation Injuries, Experimental / Q000628:therapy*; D051381:Rats; D013601:T-Lymphocytes / Q000637:transplantation*; D014182:Transplantation, Autologous
D003037:Cobalt Radioisotopes
Vliianie autotransplantatsii timotsitov na postluchevuiu regeneratsiiu krovetvoreniia