Analysis of bacteriophage deoxyribonucleic acid sequences methylated by host- and R-factor-controlled enzymes.
Phages lambda and fd were propagated in Escherichia coli strains that have either host K-12 or the N-3 R-factor deoxyribonucleic acid-cytosine methylase activity. Pyrimidine tracts containing 3H-labeled 5-methylcytosine (MeC) were analyzed; in all cases, the major methylated sequence was 5' ... C-MeC-T ... 3'.
D001483:Base Sequence; D003090:Coliphages / Q000032:analysis* / Q000378:metabolism; D004248:DNA (Cytosine-5-)-Methyltransferases / Q000378:metabolism*; D004279:DNA, Viral / Q000032:analysis* / Q000378:metabolism; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000201:enzymology; D005796:Genes; D008745:Methylation; D008780:Methyltransferases / Q000378:metabolism*; D011815:R Factors
D004279:DNA, Viral; D008780:Methyltransferases; D004248:DNA (Cytosine-5-)-Methyltransferases