Chronic painless hematuria and urethral bleeding as the presenting manifestations of Osler-Weber-Rendu disease.
A case of a young man with profound iron deficiency anemia, chronic painless hematuria and urethral bleeding is presented. He had the typical cutaneous findings of Osler-Weber-Rendu disease (hereditary hemorrhagic telangiectasia). Appropriate urological studies demonstrated bladder and urethral telangiectases, with no other explanation for the bleeding. Osler-Weber-Rendu disease should be considered in the differential diagnosis of chronic painless hematuria.
D000328:Adult; D000747:Anemia, Hypochromic / Q000175:diagnosis; D002908:Chronic Disease; D003558:Cystoscopy; D003937:Diagnosis, Differential; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis; D006417:Hematuria / Q000175:diagnosis*; D006470:Hemorrhage / Q000175:diagnosis*; D006801:Humans; D008297:Male; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000175:diagnosis*; D014522:Urethral Diseases / Q000175:diagnosis*; D001745:Urinary Bladder Diseases / Q000175:diagnosis