Short induction treatment in acute granulocytic leukemia.
Short treatment with four cytostatics in acute granulocytic leukemia induced aplasia and reduction of total leukemic cells in 50 over 59 patients. Complete remission occured in 30 and 20 died with infectious complications during induction. Short induction treatment allowed a reduction of induction period and so a reduction of high risk period of induction before completion of complete remission.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003561:Cytarabine / Q000627:therapeutic use; D003630:Daunorubicin / Q000627:therapeutic use; D004334:Drug Administration Schedule; D005260:Female; D005334:Fever / Q000209:etiology; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D011765:Pyruvaldehyde / Q000627:therapeutic use; D012075:Remission, Spontaneous; D018805:Sepsis / Q000209:etiology
D000970:Antineoplastic Agents; D003561:Cytarabine; D011765:Pyruvaldehyde; D002955:Leucovorin; D008727:Methotrexate; D003630:Daunorubicin