[Phagocytosis of cell wall defective bacteria by human macrophages (author's transl)].
Statistically significant better phagocytosis of spheroplasts was found by comparing the rate of phagocytosis of normal and Penicillin-G induced cell wall defective bacterial (spheroplasts) by human macrophages in isotonic media using a Proteus mirabilis strain as test organism. This provides additional information concerning the minor role of cell wall defective bacteria as persisters in chronic infections.
D001424:Bacterial Infections; D002908:Chronic Disease; D006801:Humans; D007231:Infant, Newborn; D009000:Monocytes; D010400:Penicillin G / Q000494:pharmacology; D010587:Phagocytosis; D011513:Proteus mirabilis; D013104:Spheroplasts / Q000187:drug effects
D010400:Penicillin G
Phagocytose von zellwanddefekten Bakterien durch menschliche Makrophagen