[Chromatographic fractionation of scraping components of frog olfactory tissues. Preparation of fractions capable of sensitizing artificial lipid membrane to odorants].
The fractionation of frog olfactory preparation by ion-exchange chromatography and gel filtration permitted to obtain fractions capable of making artificial lipid membranes sensitive to odorants, such as camphora, musc ambrette and linalool. The sensitizing agent present in active fractions is a high-molecular-weight (m.w. 100,000) protein containing substance. It is suggested that this agent is a component of a special transport system which may carry the odorous molecules to olfactory receptor cells or to remove them from olfactory tissues.
D000818:Animals; D001001:Anura; D002490:Central Nervous System / Q000502:physiology*; D008563:Membrane Lipids / Q000502:physiology*; D008567:Membranes, Artificial; D008970:Molecular Weight; D009419:Nerve Tissue Proteins / Q000302:isolation & purification / Q000502:physiology*; D009812:Odorants; D009833:Olfactory Pathways / Q000502:physiology*; D011896:Rana temporaria; D012903:Smell; D013056:Spectrophotometry, Ultraviolet
D008563:Membrane Lipids; D008567:Membranes, Artificial; D009419:Nerve Tissue Proteins
Khromatograficheskoe razdelenve komponentov soskoba oboniatel'noĭ vystilki liagushki. Poluchenie fraktsii, sposobnykh sensibilizirouat' isku sstvennye fosfolipidnye membrany k deĭstviiu pakhuchikh veshchestv.