[Protein-lipid interactions during lipid peroxidation in photoreceptor membranes].
It has been shown that chemical modification of hydrophobic lipid phase (lipoperoxidation) of outer segments membrane discs of frog retina rods brings about weakening protein-lipid interactions in the photoreceptor membrane. As a result of this extraction of rhodopsin with anion detergent (sodium cholate) in the concentrations not exceeding the critical concentration of micelloformation increases, and spontaneous release of rhodopsin into water phase is observed. At the same time the number of phospholipid molecules extracted in lipoprotein rhodopsin complex from the membranes of outer segments decreases 3-4-fold.
D000818:Animals; D001001:Anura; D005136:Eye Proteins / Q000378:metabolism*; D066298:In Vitro Techniques; D050356:Lipid Metabolism; D008074:Lipoproteins / Q000378:metabolism; D008566:Membranes / Q000378:metabolism; D010545:Peroxides / Q000378:metabolism*; D010786:Photoreceptor Cells / Q000378:metabolism*; D011896:Rana temporaria; D012243:Rhodopsin / Q000378:metabolism
D005136:Eye Proteins; D008074:Lipoproteins; D010545:Peroxides; D012243:Rhodopsin
Belok-lipidnye vzaimodeĭstviia pri perekisnom okislenii lipidov v fotoretseptornoĭ membrane