Combined pharmacokinetic and pharmacodynammc studies in man of the adrenergic beta1-receptor antagonist metoprolol.
D000284:Administration, Oral; D000328:Adult; D001682:Biological Availability; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D006207:Half-Life; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D010647:Phenyl Ethers / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D005082:Physical Exertion; D011412:Propanolamines / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D013997:Time Factors
D010647:Phenyl Ethers; D011412:Propanolamines