title: Chymoral in the treatment of lumbar disc prolapse.
abstract: Ninety-three patients with lumbar disc prolapse of less than six months duration were treated with Chymoral or an identical placebo in a double-blind study. Those patients given Chymoral exhibited significantly greater improvement of straight-leg raising and received significantly fewer analgesics. However, no difference was apparent with regard to other parameters, and similar numbers from both groups required further therapy. Over-all, the value of Chymoral in the treatment of lumbar disc prolapse seemed little better than a placebo.
mesh_terms: D000328:Adult; D002918:Chymotrypsin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010919:Placebos; D014357:Trypsin / Q000627:therapeutic use*
chemical_list: D010919:Placebos; D002918:Chymotrypsin; D014357:Trypsin