Distribution of cytophilic and anti-macrophage antibody on the macrophage surface.
The binding of cytophilic antibody to the macrophage surface results in patterns of distribution similar to those obtained when specific anti-macrophage antibody is used. These patterns are (a) diffuse circumferential binding at 4 degrees C, and (b) capping at 37 degrees C. The non-random distribution of the cytophilic antibody suggests that it binds to certain well-defined sites on the macrophage membrane.
D000818:Animals; D000917:Antibody Formation; D000937:Antigen-Antibody Reactions; D001666:Binding Sites, Antibody; D005455:Fluorescent Antibody Technique; D006168:Guinea Pigs; D007106:Immune Sera / Q000302:isolation & purification; D007111:Immunity, Cellular; D008264:Macrophages / Q000276:immunology*; D011817:Rabbits; D011947:Receptors, Antigen, B-Cell / Q000032:analysis*
D007106:Immune Sera; D011947:Receptors, Antigen, B-Cell