Insertion of a minor protein into the outer membrane of Escherichia coli during inhibition of lipid synthesis.
The antibiotic cerulenin, a specific inhibitor of fatty acid synthetase systems, was used to demonstrate that a minor protein component of the outer membrane of Escherichia coli, which serves as the receptor for the phage lambda, can be synthesized and inserted into the outer membrane during inhibition of lipid synthesis.
D000327:Adsorption; D000935:Antifungal Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000378:metabolism*; D002458:Cell Fractionation; D002473:Cell Wall / Q000378:metabolism; D002569:Cerulenin / Q000494:pharmacology*; D003090:Coliphages; D004926:Escherichia coli / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D008055:Lipids / Q000096:biosynthesis*; D008320:Maltose / Q000378:metabolism; D010710:Phosphates / Q000378:metabolism; D010743:Phospholipids / Q000096:biosynthesis; D010761:Phosphorus Radioisotopes
D000935:Antifungal Agents; D001426:Bacterial Proteins; D008055:Lipids; D010710:Phosphates; D010743:Phospholipids; D010761:Phosphorus Radioisotopes; D002569:Cerulenin; D008320:Maltose; D005947:Glucose