title: Antinuclear factor-positive mental depression: a single disease entity?
abstract: Antinuclear factor (ANF) was present in the serum of about 30% of 53 patients newly admitted to the psychiatric hospital because of mental depression. Clinically, ANF-positive depression closely resembles manic-depressive psychosis but tends to be more resistant to treatment. It is suggested that ANF-positive depression may be a quite distinctive disease.
mesh_terms: D000275:Adjustment Disorders / Q000276:immunology; D000328:Adult; D000367:Age Factors; D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis*; D000928:Antidepressive Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000276:immunology; D002908:Chronic Disease; D003863:Depression / Q000276:immunology*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis
chemical_list: D000974:Antibodies, Antinuclear; D000928:Antidepressive Agents