New high-molecular decomposition products of natamycin (pimaricin) with intact lactone-ring.
Mild acid treatment of natamycin (IV) results in biologically inactive aponatamycin (VI), an amphoteric substance with some natamycin-like chemical and physical properties. Aponatamycin contains one natamycin- and one natamycinolide-moiety. More drastic acid degradation of natamycin eliminates the aminosugar under formation of the dimer (VII) of  the hypothetical aglycone of natamycin, natamycinolide (V) as well as a non-ionic compound, the dimer of the 12-decarboxy-11-anhydro analogue of natamycinolide.
D055598:Chemical Phenomena; D002621:Chemistry; D003956:Dialysis; D006868:Hydrolysis; D007783:Lactones; D008970:Molecular Weight; D010866:Natamycin; D009994:Osmolar Concentration; D012995:Solubility
D007783:Lactones; D010866:Natamycin