title: Profile of high risk in people known to have coronary heart disease: A review.
abstract: A review of the current literature of the high-risk factors associated with cardiac morbidity and mortality in patients with established coronary heart disease is presented. Univariate risk factors include age, comorbidity, characteristics of the index coronary event, electrocardiographic findings including ventricular premature beats and response to exercise tests, angiographic severity of the coronary disease, cigarette smoking, psychosocial status, and the chronometric interval after the index coronary event. Multivariate analysis of risk factor combinations is discussed. Risk reduction requires not only an understanding of the clinical course of a disease process, but also, modification of the amenable factors which contribute to excess risk of death.
mesh_terms: D000208:Acute Disease; D000328:Adult; D000367:Age Factors; D000368:Aged; D000787:Angina Pectoris / Q000401:mortality; D000790:Angiocardiography; D003327:Coronary Disease / Q000150:complications / Q000401:mortality*; D048909:Diabetes Complications; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality; D011336:Probability; D012306:Risk; D012907:Smoking; D013997:Time Factors