An outbreak of type-C botulism in three-weeek-old broilers.
Botulism was diagnosed in 3-week-old broilers from clinical signs, absence of postmortem and histopathological lesions, and demonstration of toxin in the serum of comatose birds. Passive immunization of mice with Clostridium botulinum type-C antitoxin protected against a challenge with serum from comatose birds containing the Cl. botulinum toxin. Total mortality for the grow-out period exceeded 27% and was not altered by water medication with penicillin. Bacitracin at 100 g per ton reduced mortality to 5-7 birds per day.
D000818:Animals; D001414:Bacitracin / Q000627:therapeutic use; D001906:Botulism / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D002645:Chickens; D003014:Clostridium botulinum / Q000302:isolation & purification; D003967:Diarrhea / Q000662:veterinary; D007422:Intestines / Q000382:microbiology; D008099:Liver / Q000382:microbiology; D051379:Mice; D010243:Paralysis / Q000662:veterinary; D010406:Penicillins / Q000627:therapeutic use; D011201:Poultry Diseases / Q000276:immunology / Q000382:microbiology
D010406:Penicillins; D001414:Bacitracin