title: Potassium translocation in yeast mitochondria and its relationship to ergostrol biosynthesis.
abstract: The energy-dependent transport and accumulation of K+ in respiring mitochondria has been found to inhibit the S-adenosylmethionine: delta-24-sterol methyltransferase enzyme of Saccharomyces cerevisiae. Potassium cation translocation is discussed as a possible regulatory mechanism over the biosynthesis of ergosterol.
mesh_terms: D004140:Dinitrophenols / Q000494:pharmacology; D004875:Ergosterol / Q000096:biosynthesis*; D008780:Methyltransferases / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism*; D012436:S-Adenosylmethionine / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000378:metabolism*; D013054:Spectrophotometry, Atomic; D013261:Sterols / Q000378:metabolism; D014634:Valinomycin / Q000494:pharmacology
chemical_list: D004140:Dinitrophenols; D013261:Sterols; D014634:Valinomycin; D012436:S-Adenosylmethionine; D008780:Methyltransferases; D011188:Potassium; D004875:Ergosterol