Surgical treatment of Candida endocarditis.
Case reports from a group of 15 patients with Candida endocarditis seen and treated at the Los Angeles-University of Southern California Medical Center between 1960 and 1974, together with a survey of other reported cases, serve to re-emphasize the importance of early diagnosis of this disease and lead to certain conclusions regarding its treatment. With medical or surgical treatment alone, the mortality for Candida endocarditis is 82 per cent. With surgery and medical treatment combined, the mortality is 20 percent. It is important to institute medical treatment as soon as diagnosis of Candida endocarditis is made and surgery must be performed as soon as possible, preferably within 24 to 48 hours or, at most, a few days after the patient has left the hospital. Close observation of the patient after discharge is important.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001344:Autopsy; D001806:Blood Urea Nitrogen; D002175:Candida; D002176:Candida albicans; D002177:Candidiasis / Q000150:complications* / Q000188:drug therapy; D004696:Endocarditis / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D013045:Species Specificity; D007507:Therapeutic Irrigation
D000666:Amphotericin B