[Influence of the daily ingestion of a total unsaponifiable extract from avocado and soy bean oils on cholesterol metabolism in the rat].
The effects of ingestion of an unsaponifiable avocado and soya extract (P.I.A.S.) on the rates of cholesterol turnover were studied in the Rat smaller than in toto greater than. The balance is the same as in control rats, but fecal and urinary excretions of cholesterol are well enhanced and transformation into bile acids is consequently reduced. The absorption coefficient of cholesterol is unchanged in spite of the presence of phytosterols in the extract. The extract having been said to have a beneficial effect on scleroderma a special study was undertaken of the skin. The GLC analysis of sterols show the very probable presence of phytosterols and a richer proportion of cholesterol, precursors particularly methostenol in the skin of rats fed on P.I.A.S. than in that of the controls. These modifications do not produce any variations in the rate of cholesterol synthesis as measured in vitro.
D000085:Acetates / Q000378:metabolism; D000375:Aging; D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism; D002250:Carbon Radioisotopes; D002782:Cholestenes / Q000032:analysis; D002784:Cholesterol / Q000378:metabolism* / Q000652:urine; D002849:Chromatography, Gas; D005243:Feces / Q000032:analysis; D007408:Intestinal Absorption / Q000187:drug effects; D009821:Oils / Q000494:pharmacology*; D010840:Phytosterols / Q000378:metabolism / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology; D051381:Rats; D012867:Skin / Q000378:metabolism; D013025:Glycine max; D013261:Sterols / Q000032:analysis; D014675:Vegetables
D000085:Acetates; D001647:Bile Acids and Salts; D002250:Carbon Radioisotopes; D002782:Cholestenes; D009821:Oils; D010840:Phytosterols; D010936:Plant Extracts; D013261:Sterols; D002784:Cholesterol
Influence de l'ingestion quotidienne d'un extrait total d'insaponifiable sur le métabolisme du cholestérol chez le rat