Immunological identification of subpopulations of mononuclear cells in sarcoid granulomas.
The quantity of both circulating B and T lymphocytes in patients with sarcoidosis is diminished, although the relative percentage of each cell type appears normal. Immunocompetent cells comprising B and T lymphocytes, plasma cells, and histiocytes have been recognized in the sarcoid granuloma and the implications of these findings have been discussed.
D001402:B-Lymphocytes / Q000276:immunology*; D006644:Histiocytes / Q000276:immunology; D006801:Humans; D010950:Plasma Cells / Q000276:immunology; D012507:Sarcoidosis / Q000276:immunology* / Q000473:pathology; D013601:T-Lymphocytes / Q000276:immunology*