title: The potential of combined modality approaches for the treatment of malignant bone tumors in children.
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D007223:Infant; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D008727:Methotrexate / Q000627:therapeutic use; D009362:Neoplasm Metastasis; D012516:Osteosarcoma / Q000628:therapy*; D011859:Radiography; D012512:Sarcoma, Ewing / Q000628:therapy*
chemical_list: D008727:Methotrexate