[Metabolism and ultrastructure of magnesium aspartate-procaine arrested hearts of rabbit and man (author's transl)].
In normothermia, mild, and deep hypothermia the metabolism and the electron microscopic structure were investigated in human and rabbit heart muscle after magnesium aspartate-procaine cardioplegia. In comparison to plain ischaemic arrest splitting of adenine nucleotides and glycogen was significantly reduced in all experiments with the induced cardioplegic arrest. For 40 min at 32 degrees C almost no changes in ultrastructure were seen in heart muscle after induced arrest, while severe and/or irreversible damages were seen in the cell structure of the heart muscle due to plain ischaemic arrest.
D000227:Adenine Nucleotides / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001224:Aspartic Acid; D003327:Coronary Disease / Q000473:pathology; D006003:Glycogen / Q000378:metabolism; D006323:Heart Arrest / Q000473:pathology*; D006324:Heart Arrest, Induced; D006352:Heart Ventricles / Q000648:ultrastructure; D006801:Humans; D007036:Hypothermia, Induced; D008274:Magnesium; D008854:Microscopy, Electron; D009206:Myocardium / Q000378:metabolism / Q000648:ultrastructure*; D011343:Procaine; D011817:Rabbits; D012151:Resuscitation; D013997:Time Factors
D000227:Adenine Nucleotides; D001224:Aspartic Acid; D011343:Procaine; D000255:Adenosine Triphosphate; D006003:Glycogen; D008274:Magnesium
Stoffwechsel und elektronenmikroskopische Feinstruktur Magnesium-aspartat-procain-stillgelegter Menschen- und Kaninchenherzen