[Determination of serum-digitalisglycoside concentrations by radioimmunoassay before, during and after operations with extracorporal circulation (author's transl)].
In 13 adult patients serum-glycoside concentrations, renal glycoside elimination and endogenic creatinine clearance were determined before, during and in the first 4 days following the operation. A postoperative digitalis cumulation has not been seen. But there was a diminished digitalis tolerance in the immediate postoperative phase. Two patients got ventricular bigeminus. The low potassium values at the same time may possibly affect the sensitivity of digitalis.
D000293:Adolescent; D000328:Adult; D003404:Creatinine / Q000652:urine; D004071:Digitalis Glycosides / Q000097:blood* / Q000652:urine; D004361:Drug Tolerance; D005112:Extracorporeal Circulation; D006801:Humans; D008875:Middle Aged; D011188:Potassium / Q000097:blood; D013997:Time Factors
D004071:Digitalis Glycosides; D003404:Creatinine; D011188:Potassium
Radioimmunologische Bestimmung der Serumglykosidkonzentration bei Eingriffen mit extrakorporaler Zirkulation