T and B origin of human lymphocytic leukaemia.
A new immunological classification of leukaemia diseases in man was assessed by using electrophoretic mobility as a cell-marker. It was found that all acute lymphocytic leukaemia analysed in childhood were T-cell leukaemia, and the majority of chronic lymphocytic leukaemia in adults were also T-cell leukaemia. The remainder, chronic lymphocytic leukaemia in adults, were B-cell leukaemia. The above statements are only partially compatible with the classification given by the most commonly used T- and B-cell markers such as rosette formation or cell-surface immunoglobulins.
D000328:Adult; D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology / Q000473:pathology*; D002462:Cell Membrane / Q000276:immunology; D002648:Child; D006801:Humans; D007104:Immune Adherence Reaction; D007122:Immunoelectrophoresis; D007136:Immunoglobulins; D007945:Leukemia, Lymphoid / Q000145:classification* / Q000473:pathology; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology*
D007136:Immunoglobulins