title: The effect of menopause on serum cholesterol in American (Pima) Indian women.
abstract: Serum cholesterol levels in Pima Indian women were investigated to determine if menopause caused these levels to rise. The mean cholesterol values of 148 pre-menopausal women aged 34-54 when age-matched with 75 post-menopausal women were not significantly different. Sixty-five women passed through menopause while under observation and were examined sequentially for an average of 6.1 years. Their mean pre- and post-menopausal cholesterol levels of 182 +/- 5 mg/100 ml and 180 +/- 5 mg/100 ml were similar. Nor did menopause alter cholesterol levels in the subgroups of these patients with diabetes mellitus. Cholesterol levels in both Pima males and females showed no age-related rise, and were 20-30% lower than white populations. This study provides additional evidence against the postulated relationship between menopause and serum cholesterol.
mesh_terms: D000328:Adult; D001130:Arizona; D002784:Cholesterol / Q000097:blood*; D002791:Cholesterol, Dietary / Q000008:administration & dosage; D003327:Coronary Disease / Q000453:epidemiology / Q000209:etiology; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000097:blood / Q000453:epidemiology; D005260:Female; D006801:Humans; D007198:Indians, North American; D008297:Male; D008593:Menopause; D008875:Middle Aged; D011446:Prospective Studies; D012306:Risk; D012737:Sex Factors
chemical_list: D002791:Cholesterol, Dietary; D002784:Cholesterol