Electron microscopic autoradiographic localization of carbocromene in the coronary vessel walls and myocardium.
The ultrastructural distribution of 14-C- and the 3-H-carbocromene in monkeys and rats showed a characteristic pattern in the coronary artery wall and the heart muscle. The radioactivity was found to be located on the coronary vessel wall mainly in the tunica media over the smooth muscle cells and in the myocardium over the contractile elements and the mitochondria.
D000284:Administration, Oral; D000818:Animals; D001345:Autoradiography; D002250:Carbon Radioisotopes; D003331:Coronary Vessels / Q000378:metabolism* / Q000648:ultrastructure; D003374:Coumarins / Q000378:metabolism*; D006016:Glycolates / Q000378:metabolism*; D006325:Heart Atria; D006352:Heart Ventricles; D007275:Injections, Intravenous; D008297:Male; D008852:Microradiography; D008854:Microscopy, Electron; D008931:Mitochondria, Muscle / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism* / Q000648:ultrastructure; D009210:Myofibrils / Q000378:metabolism; D051381:Rats; D012519:Sarcoplasmic Reticulum / Q000378:metabolism; D014316:Tritium
D002250:Carbon Radioisotopes; D003374:Coumarins; D006016:Glycolates; D014316:Tritium