title: [The role of the buds and myoblasts in reparative regeneration of muscle fibers of the skeletal type].
abstract: The reparative regeneration of the tibial muscle of the frog was studied. Both light proper-muscular nuclei and dark subsarcolemmal ones (from the author's point of view--the nuclei of cells-satellites) take part in it. The former are not labelled with H-3-thymidine do not divide mitotically, do not incorporate H-3-uridine and multiply by fragmentation. During the latter they lyse. From them the end buds are formed which develop into "primary" myosymplasts. The second type nuclei, when secreting RNA and DNA, form myoblasts which divide mitotically. The primary myosymplasts serve as a framework along which the myoblasts move and participate in the myofibrilles formation. New muscle fibres develop through a confluence of myoblasts with one another, first forming sharply basophilic "secondary" myosymplasts on the surface of slightly basophilic "primary" ones. They become thicker through multiple deposition of joining myoblasts on the surface. The last of them remain isolated, apparently, in the role of new satellites.
mesh_terms: D000818:Animals; D001001:Anura; D001345:Autoradiography; D002467:Cell Nucleus / Q000378:metabolism; D004247:DNA / Q000096:biosynthesis*; D009132:Muscles / Q000378:metabolism / Q000502:physiology* / Q000648:ultrastructure; D012313:RNA / Q000096:biosynthesis*; D012038:Regeneration; D013936:Thymidine / Q000378:metabolism; D014316:Tritium; D014529:Uridine / Q000378:metabolism
chemical_list: D014316:Tritium; D012313:RNA; D004247:DNA; D013936:Thymidine; D014529:Uridine
vernacular_title: O roli pochek i mioblastov pri reparativnoĭ regeneratsii myshechnykh volokon skeletnogo tipa