title: Radiation therapy of brain tumors in children.
abstract: The case histories of 124 children irradiated for brain tumors were reviewed to determine survival rate and functional prognosis, with special reference to somatic growth. Five-year survival rates (29% of 97 patients with gliomas and 70% of 27 patients with non-gliomatous tumors) were approximately the same as in our adult series, despite the differences in histology and predilection. Although 70% of 42 long-term survivors had active, useful lives, stunted growth was observed in 15 of them. More attention should be directed to the growth of children irradiated for brain tumors.
mesh_terms: D000293:Adolescent; D001254:Astrocytoma / Q000532:radiotherapy; D001932:Brain Neoplasms / Q000532:radiotherapy*; D001933:Brain Stem; D002528:Cerebellar Neoplasms / Q000532:radiotherapy; D002551:Cerebral Ventricle Neoplasms / Q000532:radiotherapy; D002648:Child; D002675:Child, Preschool; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003397:Craniopharyngioma / Q000532:radiotherapy*; D004806:Ependymoma / Q000532:radiotherapy*; D005260:Female; D005720:Gamma Rays; D005910:Glioma / Q000532:radiotherapy*; D006130:Growth Disorders / Q000209:etiology; D006801:Humans; D007223:Infant; D008297:Male; D008527:Medulloblastoma / Q000532:radiotherapy*; D008579:Meningioma / Q000532:radiotherapy*; D008636:Mesencephalon; D009837:Oligodendroglioma / Q000532:radiotherapy; D010871:Pinealoma / Q000532:radiotherapy; D010911:Pituitary Neoplasms / Q000532:radiotherapy; D011379:Prognosis; D011878:Radiotherapy / Q000009:adverse effects; D014965:X-Rays
chemical_list: D003037:Cobalt Radioisotopes