title: An investigation of the chemical contact lens problem.
abstract: An evaluation of the "chemical trapping premise" was made to determine if, in fact, chemicals do accumulate behind a contact lens if a wearer encounters chemical splash. Photographs were taken to document the effect of chemical splashes. A photograph of a normal eye, Fig 7, taken prior to the insertion of a contact lens is included for purposes of comparison. Under the conditions investigated, it was demonstrated that, for liquid irritant exposures, eyes are afforded more protection when wearing contact lenses than when not. Test results suggest the contact lens acts as a barrier to the irritant on the cornea. The investigators postulate that lid spasm occurs, causing the lens to tighten against the cornea, thereby effectively sealing off the area under the lens. Since the "barrier" effect appears to be a function of time, more testing of this variable is warranted. Moreover, further investigation is indicated using a broader spectrum of irritants and an extended environmental exposure to dust and vapors.
mesh_terms: D000085:Acetates / Q000633:toxicity; D000096:Acetone / Q000633:toxicity; D000818:Animals; D002057:Burns, Chemical; D002082:Butylamines / Q000633:toxicity; D003261:Contact Lenses / Q000009:adverse effects*; D065306:Corneal Injuries; D004781:Environmental Exposure; D005126:Eye Burns / Q000209:etiology; D007509:Irritants / Q000633:toxicity*; D007634:Keratitis / Q000139:chemically induced; D009784:Occupational Diseases / Q000139:chemically induced*; D011482:Protective Devices; D011817:Rabbits; D013997:Time Factors
chemical_list: D000085:Acetates; D002082:Butylamines; D007509:Irritants; D000096:Acetone