Successful use of combination chemotherapy in pure red cell aplasia associated with malignant lymphoma, histiocytic type.
A case of pure red cell aplasia developing in a woman aged 78 is reported. Biopsy of an enlarged axillary lymph node disclosed a malignant lymphoma, histiocytic type. Therapy with intermittent cyclophosphamide and prednisone was instituted. There was rapid remission of the red cell aplasia. Clinical recurrence of the histiocytic lymphoma has not occurred.
D000368:Aged; D000741:Anemia, Aplastic / Q000188:drug therapy* / Q000209:etiology; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications*; D011241:Prednisone / Q000627:therapeutic use*
D003520:Cyclophosphamide; D011241:Prednisone