[Ultrastructural changes in the capillaries of the renal glomeruli and parenchyma following acute ischemia].
The ultrastructural changes of the capillaries of the renal glomerule and the parenchyma of the kidney were studied in 20 albino rats after clamping the vascular peduncle of the left kidney for 30 minutes, 1, 2 and 3 hours without a following recovery of the blood flow. In 30 minutes pinocytosis was increased in the cytoplasm of endothelial cells of glomerule capillaries. In the cytopodia there appeared vacuoles. The brush border was swallen, its separate growings acquired a bulb-like shape. Microplasmatosis of the internal plasmolemma of the endothelium appeared after 1--2--3-hour ischemia. The basal layer of capillaries became wider, with uneven contours and partly homogenized. Cytopodia became deformed and more close. The brush border was rejected in some places. Mitochondria were swallen, crists lost their parallelism, their amount became less.
D000208:Acute Disease; D000818:Animals; D002196:Capillaries / Q000648:ultrastructure*; D002462:Cell Membrane; D004727:Endothelium; D004848:Epithelium; D007511:Ischemia / Q000473:pathology*; D007668:Kidney / Q000098:blood supply* / Q000648:ultrastructure; D007678:Kidney Glomerulus / Q000648:ultrastructure*; D007684:Kidney Tubules / Q000648:ultrastructure; D010873:Pinocytosis; D051381:Rats; D013997:Time Factors
Ul'trastrukturnye izmeneniia kapilliarov pochechnykh klubochkov i parenkhimy pochki posle ostroĭ ishemii