[Electron microscopic study of the formation of pancreatic endocrine A-cells from acinar epithelium in normal and experimental conditions].
Electron microscope studies in the pancreas of intact white rats and cats and after folliculin administration showed presence of acinar-islet cells with zymogen and endocrine A-granules. Different structure organellas, different amount of zymogen and incretory granules in these cells gave an idea of the process of acino-insular transformation. At later stages of the transformation, participation of the elements of laminar complex of the transitional cells in formation of secretory A-granules, was noted. Presence of the acinar-islet cells in normal and a high amount of them in the pancreas of experimental animals corroborated the essential role of the acinar-islet transformation in the genesis of A-cells of the Langerhans islets.
D000818:Animals; D002415:Cats; D002466:Cell Nucleolus; D002467:Cell Nucleus; D004970:Estrone / Q000494:pharmacology; D006056:Golgi Apparatus; D007801:Langerhans Cells; D008297:Male; D008854:Microscopy, Electron; D008928:Mitochondria; D010179:Pancreas / Q000166:cytology* / Q000187:drug effects; D051381:Rats
D004970:Estrone
Elektronnomikroskipicheskoe izuchenie obrazovaniia éndokrinnykh A-kletok podzheludochnoĭ zhelezy iz atsinarnogo épiteliia v norme i éksperimente