title: Varicocelectomy as therapy in male infertility: a study of 504 cases.
abstract: Over a ten-year period, surgical correction of varicocele was performed on 504 selected subfertile men. They were followed up for at least one year after surgery. Semen quality was improved in 71% and 55% of the wives became pregnant. Statistically, the results were better in terms of semen quality improvement and pregnancy for patients who had preoperative sperm counts over 10 million/ml (88% improved, 68% pregnancy rate) than for patients who had preoperative sperm counts of less than 10 million/ml (33% improved, 23% pregnancy rate). The empirical use of postoperative human chorionic gonadotropin therapy in this latter group improved results significantly (56% improved, 44% pregnancy rate).
mesh_terms: D002452:Cell Count; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D008026:Ligation; D008297:Male; D010808:Physical Examination; D011183:Postoperative Complications; D011247:Pregnancy; D012008:Recurrence; D013094:Spermatozoa; D013223:Statistics as Topic; D006848:Testicular Hydrocele / Q000209:etiology / Q000601:surgery; D014646:Varicocele / Q000150:complications / Q000601:surgery*
chemical_list: D006063:Chorionic Gonadotropin