Concentration of serotonin in intestine and factors affecting its release.
The concentration of serotonin in the female chicken intestine (10.79 mug/g wet tissue) was significantly higher than in the male (7.98 mug/g). The release of serotonin from an isolated perfused intestine was studied. The intestine continually releases serotonin at the rate of 10 ng per g/min. A number of substances, including glycine, epinephrine, and acetylcholine, caused a significant release of serotonin, with acetylcholine having the greatest effect. Histamine or electrical stimulation did not affect the release of serotonin.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D002645:Chickens; D004558:Electric Stimulation; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D005769:Gastrointestinal Motility; D005998:Glycine / Q000494:pharmacology; D006632:Histamine / Q000494:pharmacology; D007421:Intestine, Small / Q000378:metabolism*; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology; D012701:Serotonin / Q000378:metabolism*; D012737:Sex Factors; D013268:Stimulation, Chemical
D012701:Serotonin; D006632:Histamine; D000109:Acetylcholine; D005998:Glycine; D009638:Norepinephrine; D004837:Epinephrine