Supraspinal interactions resulting from experimental dorsal column stimulation.
Experiments were performed on rhesus monkeys to examine the hypothesis that stimulation with dorsal column electrodes of the type implanted clinically could alter the responses evoked in supraspinal nuclei through pathways in the ventral quadrant of the spinal cord. Dorsal column stimulation did produce changes in responses evoked in supraspinal nuclei; this effect could not be ascribed to a conduction block in ascending pathways. These results suggest that the mechanism of action of the dorsal column stimulator need not be dependent on interactions in the dorsal horn.
D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology*; D003201:Computers; D004558:Electric Stimulation / Q000379:methods; D004567:Electrodes, Implanted; D005703:Gallamine Triethiodide / Q000494:pharmacology; D008251:Macaca; D009431:Neural Conduction; D009434:Neural Pathways; D009991:Oscillometry; D010148:Intractable Pain / Q000628:therapy; D013116:Spinal Cord / Q000502:physiology*; D013133:Spinothalamic Tracts / Q000502:physiology*; D013787:Thalamic Nuclei / Q000502:physiology
D005703:Gallamine Triethiodide