Pharmacology of ethaverine HC1: human and animal studies.
The pharmacology of ethaverine hydrochloride has been studied in humans and animals. The studies determined that the drug was an effective smooth muscle relaxant. The ethaverine hydrochloride produced significant increase in peripheral blood flow in patients with occlusive artery disease. In longitudinal studies there was no evidence of toxic effects in patients receiving 100 mg ethaverine HCl three times a day.
D000328:Adult; D000368:Aged; D000818:Animals; D001157:Arterial Occlusive Diseases / Q000188:drug therapy; D001775:Blood Circulation / Q000187:drug effects; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D008875:Middle Aged; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010208:Papaverine / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000633:toxicity; D010919:Placebos
D010919:Placebos; D010208:Papaverine