title: [Liver biopsy and blood serum enzyme content in patients with rheumatic heart disease with circulatory insufficiency].
abstract: Puncture biopsy of the liver and a comparison of the blood serum enzymes-lactate-dehydrogenase and fructose-1-phosphate-aldolase-with the nature of histomorphological alterations were effected in 18 patients with rheumatic heart diseases, circulatory insufficiency of the II-III degree and rheumatism in the I-II stage of activity. Morphological changes in the liver were not specific, being characterized largely by congestive manifestations and deranged intrahepatic circulation. With a declining level of glycogen and nucleoproteins in the hepatocytes the blood serum of such patients showed an increased content of fructose-1-phosphate-aldolase and lactate-dehydrogenase. Histomorphological analysis of the puncture material facilitate the evaluation of the nature of intravital changes in the liver of patients with different degrees of circulatory insufficiency.
mesh_terms: D000328:Adult; D000429:Alcohol Oxidoreductases / Q000097:blood; D000446:Aldehyde-Lyases / Q000097:blood; D001707:Biopsy, Needle; D004796:Clinical Enzyme Tests; D005260:Female; D005636:Fructosephosphates; D006333:Heart Failure / Q000175:diagnosis / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008099:Liver / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology*; D008102:Liver Circulation; D008297:Male; D008875:Middle Aged; D012214:Rheumatic Heart Disease / Q000201:enzymology / Q000473:pathology / Q000503:physiopathology*; D000637:Transaminases / Q000097:blood
chemical_list: D005636:Fructosephosphates; D000429:Alcohol Oxidoreductases; D007770:L-Lactate Dehydrogenase; D000637:Transaminases; D000446:Aldehyde-Lyases
vernacular_title: Gepatobiopsiia i soderzhanie fermentov v syvorotke krovi u bol'nykh revmaticheskimi porokami serdtsa s nedostatochnost'iu krovoobrashcheniia