Initial studies on the cytotoxic action of maytansine, a novel ansa macrolide.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology* / Q000627:therapeutic use; D002478:Cells, Cultured; D007930:Leucine / Q000378:metabolism; D007939:Leukemia L1210; D007942:Leukemia, Experimental / Q000188:drug therapy; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008938:Mitosis / Q000187:drug effects; D009025:Morpholines / Q000494:pharmacology / Q000627:therapeutic use; D009363:Neoplasm Proteins / Q000378:metabolism; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D013936:Thymidine / Q000378:metabolism; D014529:Uridine / Q000378:metabolism
D000903:Antibiotics, Antineoplastic; D009025:Morpholines; D009363:Neoplasm Proteins; D010936:Plant Extracts; D007930:Leucine; D013936:Thymidine; D014529:Uridine