Studies of urinary bladder dysfunction in amyloidosis with polyneuropathy.
Eight male patients with amyloid polyneuropathy, seven of whom had symptoms of dysfunction of the urinary bladder, were studied by cystometry and micturition analysis and compared with eight male controls. Most of the patients with amyloidosis had an increased bladder capacity. The need to micturate was reduced, and urine retention was common. In most of them detrusor function could not be demonstrated. The maximal flow rate was usually diminished and the resistance to flow elevated. In some of the patients there was increased rigidity of the bladder wall.
D000328:Adult; D000686:Amyloidosis / Q000150:complications / Q000503:physiopathology*; D003558:Cystoscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D011115:Polyneuropathies / Q000150:complications / Q000503:physiopathology*; D011312:Pressure; D014521:Urethra / Q000503:physiopathology; D001743:Urinary Bladder / Q000503:physiopathology*; D014546:Urinary Catheterization; D014554:Urination