Ultrastructure of a mixed form of calcinosis.
An unusual form of calcinosis is described presenting a joint occurrence of calcinosis circumscripta and calcinosis universalis. Ultrastructurally, the mineral constituent is of much higher crystallinity than that of normal bone, and includes a rare kind of carbonate apatite. The crystals of the specimen were needle-like and hexagonal, in juxtaposition to normal collagen fibrils. Supposedly, the development of the calcifiable matrix is different in calcinosis and bone tissue.
D001031:Apatites / Q000032:analysis; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D002254:Carbonates / Q000032:analysis; D003094:Collagen; D003460:Crystallization; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D011859:Radiography; D014961:X-Ray Diffraction
D001031:Apatites; D002254:Carbonates; D003094:Collagen