Composition of liver histones in aging rat and mouse.
In contrast to the earlier reports on the age-dependent reduction of the ratio of F3 plus F2al plus F2a2 / Fl plus F2b in rat liver histones and the reduction of arginine-rich histone (F3 or III) in beef thymus, the result obtained by high-resolution polyacrylamide gel electrophoresis of histones shows no apparent age-related change in the proportion of any histone fraction of mouse and rat liver chromatin.
D000375:Aging; D000818:Animals; D002458:Cell Fractionation; D002843:Chromatin / Q000032:analysis*; D003201:Computers; D003720:Densitometry; D004591:Electrophoresis, Polyacrylamide Gel; D006657:Histones / Q000032:analysis*; D008099:Liver / Q000032:analysis*; D051379:Mice; D008810:Mice, Inbred C57BL; D051381:Rats; D011919:Rats, Inbred Strains; D013053:Spectrophotometry; D014461:Ultracentrifugation
D002843:Chromatin; D006657:Histones