A new cocktail for liquid scintillation counting of aqueous radioimmunoassay-samples.
The aim of this investigation was to find a scintillation mixture for counting up to 1 ml of plasma. We succeeded in obtaining a mixture of xylene/Triton X-100/mono- and di-butylphosphate, and called it Plasmasol. The properties were ideal for radioimmunoassays of steroids.  Good dissolving properties, high counting efficiency, absence of chemiluminescence and a good stability and reproducibility with respect to the disintegrations per minute were achieved. The cost was only 25% of the commercially available ready-to-use liquid scintillation mixtures, with which a comparison was made.
D001769:Blood; D002250:Carbon Radioisotopes / Q000032:analysis*; D004355:Drug Stability; D005069:Evaluation Studies as Topic; D007202:Indicators and Reagents; D009943:Organophosphorus Compounds; D011092:Polyethylene Glycols; D011863:Radioimmunoassay; D012995:Solubility; D013256:Steroids / Q000032:analysis; D013739:Testosterone / Q000032:analysis*; D014316:Tritium / Q000032:analysis*; D014992:Xylenes
D002250:Carbon Radioisotopes; D007202:Indicators and Reagents; D009943:Organophosphorus Compounds; D013256:Steroids; D014992:Xylenes; D014316:Tritium; D011092:Polyethylene Glycols; D013739:Testosterone