title: Primary adenocarcinoma of the esophagus arising in a columnar-lined esophagus.
abstract: A patient presenting with dysphagia and weight loss was found to have a large midesophageal mass. Five biopsies indicated only adenoma but a brush cytology specimen under direct vision was diagnostic of adenocarcinoma. Esophagotomy and resection of tumor, with follow-up radiotherapy were performed; histologic examination confirmed the diagnosis. To date, there has been no recurrence of the tumor. This patient was subsequently found to have a columnar-lined esophagus. Since columnar-lined esophagus may predispose to malignancy, this case illustrates the diagnostic importance of direct-vision cytology in patients with columnar-lined esophagus.
mesh_terms: D000230:Adenocarcinoma / Q000209:etiology* / Q000601:surgery; D001706:Biopsy; D004724:Endoscopy; D004848:Epithelium / Q000473:pathology; D004938:Esophageal Neoplasms / Q000209:etiology* / Q000601:surgery; D004947:Esophagus / Q000473:pathology* / Q000601:surgery; D005471:Fluoroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged