[Effect of the degree of hypothermia on the intensity of DNA, RNA and protein synthesis in a tumor and in normal tissue].
In rats were Heren carcinoma at the initial stage of hypothermia (30-31 degrees C) in hepatic tissues there was observed at a greater intensity of protein and nucleic acids synthesis contrary to its marked reduction in tumor tissues. In tumor tissues a cessation of protein synthesis was observed at 20-21 degrees C. while that of nucleic acids at 14-15 degrees C. Under these regimens of hypothermia no complete cessation of protein and nucleic acids synthesis in hepatic tissue occurred. However, their synthesis was markedly suppressed.
D000818:Animals; D001345:Autoradiography; D001831:Body Temperature; D004247:DNA / Q000096:biosynthesis*; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D007035:Hypothermia / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008715:Methionine / Q000378:metabolism; D009363:Neoplasm Proteins / Q000096:biosynthesis*; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000378:metabolism*; D014176:Protein Biosynthesis; D012313:RNA / Q000096:biosynthesis*; D012334:RNA, Neoplasm / Q000096:biosynthesis*; D051381:Rats; D013997:Time Factors; D014316:Tritium; D014529:Uridine / Q000378:metabolism
D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; D012334:RNA, Neoplasm; D014316:Tritium; D012313:RNA; D004247:DNA; D008715:Methionine; D014529:Uridine
Vliianie stepeni gipotermii na intensivnost' sinteza DNK, RNK i belka v opukholi i normal'noĭ tkani