[New esters of prednisolone and triamcinolone acetonide and their anti-inflammatory activity].
Seventeen acids with diphenylyl and cyclohexylphenyl groups were esterified with the hydroxyl group at position 21 of prednisolone and triamcinolone acetonide. Some of these esters showed marked activity against carrageenin edema and Selye spots in the rat, especially on local application.
D000284:Administration, Oral; D000287:Administration, Topical; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis* / Q000627:therapeutic use; D004487:Edema / Q000188:drug therapy; D004952:Esters; D011239:Prednisolone / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000627:therapeutic use; D051381:Rats; D014222:Triamcinolone Acetonide / Q000138:chemical synthesis* / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D004952:Esters; D011239:Prednisolone; D014222:Triamcinolone Acetonide
Nuovi esteri del prednisolone e del triamcinolone acetonide e loro attività antiinfiammatoria