[Paraneoplastic precocious puberty in a child. Mediastinal teratoma with chorionic gonadotropin secretion].
A case of precocious puberty in a 5-years old boy with a rapid increase of androgens, small testes, a high level of urinary bioassayable gonadotrophins, but no response of pituitary gonadotrophins of LH-RH injection. The cause was a mediastinal teratoma secreting chorionic gonadotrophin (HCG and beta subunit).
D000918:Antibody Specificity; D002675:Child, Preschool; D006063:Chorionic Gonadotropin / Q000276:immunology / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000378:metabolism / Q000601:surgery; D011629:Puberty, Precocious / Q000209:etiology*; D013724:Teratoma / Q000150:complications* / Q000378:metabolism / Q000601:surgery; D013737:Testis / Q000473:pathology; D013739:Testosterone / Q000097:blood / Q000652:urine
D006063:Chorionic Gonadotropin; D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone
Puberte precoce paraneoplasique chez un enfant. Teratome mediastinal avec secretion de gonadotrophine chorionique