title: Mezerein: antileukemic principle isolated from Daphne mezereum L.
abstract: An alcohol-water extract of Daphne mezereum L., a plant widely used in folk medicine for treating cancers, showed antileukemic activity against the P-388 lymphocytic leukemia in mice. Systematic fractionation of the extract has led to isolation and characterization of mezerein as the principal antileukemic component.
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000627:therapeutic use; D007942:Leukemia, Experimental / Q000188:drug therapy*; D007945:Leukemia, Lymphoid / Q000188:drug therapy*; D051379:Mice; D010936:Plant Extracts; D010946:Plants, Medicinal
chemical_list: D000970:Antineoplastic Agents; D010936:Plant Extracts