Effect of glucose priming on insulin response in the premature infant.
Our paper deals with premature infants in the first twenty-four hours of life and reports the effect of a preinfusion of glucose on glucose administration. Glucose infusion (2.5 gm.) resulted in a slight elevation of serum insulin. When this administration of glucose was preceded by a two-hour infusion of glucose, there was a striking increase in serum insulin.
D005947:Glucose / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007263:Infusions, Parenteral; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D012965:Sodium Chloride / Q000378:metabolism; D013268:Stimulation, Chemical; D013997:Time Factors
D007328:Insulin; D012965:Sodium Chloride; D005947:Glucose