title: Analgesic abuse in urological practice.
abstract: Thirty-three patients seen in a urological department had taken large doses of analgesic for prolonged periods of time. In 9 cases a diagnosis of pyramidal necrosis was established, while 4 other had pyelographic evidence of pyelonephritis, and analgesic abuse was probably an important aetiological factor in their renal condition. Analgesic nephropathy is easily overlooked unless patients are questioned routinely regarding their intake of analgesic. It is important to identify the group of patients without evidence of serious renal disease who are taking excessive quantities of analgesic and to urge them to abandon the practice.
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced; D000328:Adult; D000368:Aged; D000740:Anemia / Q000139:chemically induced; D001241:Aspirin / Q000506:poisoning*; D003061:Codeine / Q000009:adverse effects; D005260:Female; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D007669:Kidney Calculi / Q000000981:diagnostic imaging; D007674:Kidney Diseases / Q000139:chemically induced*; D007681:Kidney Papillary Necrosis / Q000139:chemically induced / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000139:chemically induced; D010615:Phenacetin / Q000506:poisoning*; D011584:Psychology; D011704:Pyelonephritis / Q000139:chemically induced; D019966:Substance-Related Disorders; D014567:Urography
chemical_list: D010615:Phenacetin; D001241:Aspirin; D003061:Codeine