[Pyrazino (1,2-a)- and 1,4-diazepino(1,2-a)indoles. II. Synthesis of 1-substituted 10-phenyl-3,4-dihydropyrazino(1,2-a)indoles and of 11-phenyl-4,5-dihydro-4H-diazepino(1,2-a)indoles].
The AA. describe the synthesis of some 1-substituted 10-phenyl-3,4-dihydropyrazino(1,2-a)indoles and 11-phenyl-4,5-dihydro-3H-1,4-diazepino(1,2-a)indoles. Preliminary pharmacological tests indicate that these products, have lower sedative and antiadrenergic activity than the compounds reported in our previous paper.
D000818:Animals; D001381:Azepines / Q000138:chemical synthesis*; D002319:Cardiovascular System / Q000187:drug effects; D006993:Hypnotics and Sedatives / Q000138:chemical synthesis; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051379:Mice; D009119:Muscle Contraction / Q000187:drug effects; D011719:Pyrazines / Q000138:chemical synthesis*
D001381:Azepines; D006993:Hypnotics and Sedatives; D007211:Indoles; D011719:Pyrazines
Pirazino(1,2-a)- E 1,4-diazepino(1,2-a)indoli. II. Sintesi di 10-fenil-3,4-diidropirazino(1,2-a)indoli e di 11-fenil-4,5-diidro-3H-1,4-diazepino(1,2-a)indoli, 1-sostituiti