The influence of emetine on the induction of interferon by poly-I: poly-C in Swiss mice.
The effect of emetine on the in vivo production of interferon by Swiss mice stimulated with poly-i: poly-C, was studied. 100 mug of emetine per mouse yielded a 16-fold increase in interferon production. Maximal production of interferon was achieved 2 h after the simultaneous injection of emetine and poly-I: poly-C.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004640:Emetine / Q000494:pharmacology*; D007372:Interferons / Q000096:biosynthesis*; D051379:Mice; D011070:Poly I-C / Q000494:pharmacology*
D007372:Interferons; D011070:Poly I-C; D004640:Emetine