Adenyl cyclase activity in Duchenne dystrophic muscle.
Adenyl cyclase activity in normal and Duchenne dystrophic muscle was assayed using a radiochemical method. In dystrophic muscle, the enzyme activity is reduced. The reduced enzyme activity and its adverse effects on energy metabolism in dystrophic patients are discussed.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D002648:Child; D004789:Enzyme Activation; D005459:Fluorides; D006801:Humans; D007545:Isoproterenol; D009132:Muscles / Q000201:enzymology*; D009136:Muscular Dystrophies / Q000201:enzymology*
D000262:Adenylyl Cyclases; D007545:Isoproterenol; D005459:Fluorides