title: Development of reversible vas deferens occlusive device: V. Flexible prosthetic devices.
abstract: In contrast to the results with rigid-ended prosthetic devices implanted in the vas deferens of the dog, effective sperm transport was obtained for prolonged periods of time with flexible-ended (all soft) devices. Such transport could be halted by device occlusion with clips or shuttle stem valves. Opening the devices resulted once again in the passage of spermatozoa, indicating that these devices may be potentially useful as reversible male contraceptives. More research is necessary to determine the cause of an overall decrease in sperm output after device implantations and to evaluate any adverse side effects of such devices. Dacron velour-covered suture rings on the devices permitted effective tissue ingrowth and prevented leakage or recanalization.
mesh_terms: D000818:Animals; D002465:Cell Movement; D004285:Dogs; D008297:Male; D019736:Prostheses and Implants; D012826:Silicone Elastomers; D013094:Spermatozoa; D013193:Stainless Steel; D014649:Vas Deferens / Q000601:surgery; D014659:Vasectomy / Q000295:instrumentation* / Q000379:methods
chemical_list: D012826:Silicone Elastomers; D013193:Stainless Steel