title: Cutaneous necrosis due to cetrimide application.
abstract: Reports of necrosis caused by quaternary ammonium compounds, such as cetrimide, are rare. The case is reported of a 77-year-old woman who was admitted to hospital for four months with cutaneous necrosis of the left foot and leg owing to the topical application of cetrimide powder.
mesh_terms: D000368:Aged; D000473:Alkanes / Q000009:adverse effects; D000740:Anemia / Q000150:complications; D000891:Anti-Infective Agents, Local / Q000009:adverse effects*; D003023:Cloxacillin / Q000627:therapeutic use; D003646:Debridement; D004485:Eczema / Q000188:drug therapy; D005260:Female; D006454:Hemoglobins; D006801:Humans; D009336:Necrosis / Q000139:chemically induced*; D010232:Paraffin / Q000627:therapeutic use; D011196:Potassium Permanganate / Q000627:therapeutic use; D000644:Quaternary Ammonium Compounds / Q000009:adverse effects*; D012871:Skin Diseases / Q000139:chemically induced*; D012874:Skin Diseases, Infectious / Q000188:drug therapy; D012882:Skin Tests; D013203:Staphylococcal Infections / Q000188:drug therapy
chemical_list: D000473:Alkanes; D000891:Anti-Infective Agents, Local; D006454:Hemoglobins; D000644:Quaternary Ammonium Compounds; D011196:Potassium Permanganate; D010232:Paraffin; D003023:Cloxacillin