title: [The antigenic structure of Toxoplasma gondii.  III. Behavior of human sera as compared with purified antigens].
abstract: 263 human serum samples obtained from 9 controls and 42 patients with clinical diagnosis suggestive for toxoplasmosis were examined by means of Sabin and Feldman's dye test (DT) in comparison with complement fixation test (CF) with a whole toxoplasma antigen.  6 out of 9 controls and 21 out of 42 patients showed analogous behaviour in both methods while the remaining ones behaved differently.  24 out of the 42 patients as well as the 9 controls were chosen between these two groups (showing concordant or discordant DT/CF behaviour) to determine the presence or absence of anti-"polysaccharide" and anti-"protein" antibodies against purified antigens by means of CF test.  Presence of anti-polysaccharide antibodies was shown in 15 subjects (4 out of 17 "DT/CF discordant" groups) and antiprotien antibodies in 8 patients (2 and 6 respectively in the two groups).  Antibodies against these two purified antigens were never shown in the 9 normal people.  Critical as well as hypothetical implications concerning the results so far obtained are discussed.
mesh_terms: D000906:Antibodies / Q000032:analysis; D000941:Antigens / Q000032:analysis / Q000302:isolation & purification; D003168:Complement Fixation Tests; D006801:Humans; D008751:Methylene Blue; D012698:Serologic Tests; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000175:diagnosis / Q000276:immunology*
chemical_list: D000906:Antibodies; D000941:Antigens; D008751:Methylene Blue
vernacular_title: Sulla struttura antigene di Toxoplasma gondii.  III. Comportamento di sieri umani nei confronti di antigeni purificati