Correction of the malabsorption of the preterm infant with a medium-chain triglyceride formula.
After receiving milk-based formula for one week, 16 preterm infants, weighing 1,300 to 1,800 gm, were fed two isocaloric formulas containing either medium-chain or long-chain triglycerides for 15 days; the alternate formula was given for a second period of identical duration. While receiving MCT, the infants had greater (P smaller than 0.01) percent fat absorption (83.4 leads to 97.1%) and weight gain (7.5 leads to 11.5 gm/kg/100 calories). Because metabolic acidosis occurred with the LCT formula, the chloride content was adjusted to that of the MCT were confirmed and, in addition, there was a higher (P smaller than .01) percent retention of nitrogen (67.3 leads to 82.1).
D001835:Body Weight; D002446:Celiac Disease / Q000178:diet therapy / Q000209:etiology; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D005243:Feces / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000178:diet therapy*; D007408:Intestinal Absorption / Q000187:drug effects; D050356:Lipid Metabolism; D008286:Malabsorption Syndromes / Q000150:complications / Q000178:diet therapy* / Q000378:metabolism; D009584:Nitrogen / Q000032:analysis / Q000378:metabolism / Q000652:urine; D014280:Triglycerides / Q000494:pharmacology / Q000627:therapeutic use*
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D014280:Triglycerides; D009584:Nitrogen