title: Uptake of radiolabeled estradiol by the canine adrenal.
abstract: Tritiated estradiol injected intravenously into 11 mongrel dogs sacrificed at 3, 7, 10, 17, and 60 min showed maximum uptake in the adrenal gland at 3-7 min. The concentrations of radioactivity in the adrenal in percent dose per gram equaled that from 131I-19-iodocholesterol. If a 131I-estradiol could be synthesized that would concentrate similarly in the adrenal, it would offer the advantage of almost instantaneous imaging after the tracer injection and a lower radiation dose.
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D000311:Adrenal Glands / Q000378:metabolism*; D000818:Animals; D004285:Dogs; D004958:Estradiol / Q000097:blood / Q000378:metabolism*; D005187:Fallopian Tubes / Q000378:metabolism; D005260:Female; D007672:Kidney Cortex / Q000378:metabolism; D007679:Kidney Medulla / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D010053:Ovary / Q000378:metabolism; D010179:Pancreas / Q000378:metabolism; D010903:Pituitary Gland, Anterior / Q000378:metabolism; D010904:Pituitary Gland, Posterior / Q000378:metabolism; D011467:Prostate / Q000378:metabolism; D014316:Tritium; D014599:Uterus / Q000378:metabolism
chemical_list: D014316:Tritium; D004958:Estradiol