title: Subdural hematoma following open-heart operations.
abstract: Six patients who died following open-heart operations were found at postmortem examination to have acute subdural hematomas. On the basis of the clinical and postmortem findings, two factors in the pathogenesis of the hemorrhage are postulated. In the presence of intraoperative heparin administration, significant hematoma formation may result from damage to the bridging dural veins from minor, inadvertent head trauma or alterations in cerebral volume from fluid shifts. Manipulation of the head in patients who have been given heparin should be undertaken with extreme care, particularly in infants. In any patient with neurological dysfunction who has also had an open-heart operation, the possibility of an expanding subdural hematoma must be considered.
mesh_terms: D001344:Autopsy; D006348:Cardiac Surgical Procedures; D002555:Cerebrospinal Fluid; D002648:Child; D002675:Child, Preschool; D003392:Cranial Sinuses / Q000293:injuries / Q000473:pathology; D006259:Craniocerebral Trauma / Q000150:complications*; D005260:Female; D006408:Hematoma, Subdural / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control; D006493:Heparin / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007427:Intracranial Pressure; D008297:Male; D011183:Postoperative Complications / Q000473:pathology / Q000517:prevention & control
chemical_list: D006493:Heparin