[Proceedings: Treatment of excessive body height in adolescents with small doses of corticoids. Demonstration and advantages. 10 cases treated with prednisone].
Treatment of great heights has always been in endocrinology, especially in the U.S.A., a problem hard to solve, estrogenotherapy being the main drug and giving more and less convincing results. We present a treatment with small doses of corticoids which seems more satisfactory starting at a level of two centimeters under the expected height. This treatment allows to get the complete join of the long bones cartilage under the influence of a normal puberty. 11 teen-agers (1 male and 10 females) have been given such a treatment at variable ages (range = 12 6/12 and 16, mean = 14 2/12). The standard dose was 15 mg per day of prednisone, 5 mg every eight hours, during 7 to 25 months, with periodical supervising of clinical, biological and radiological state. Results are excellent on growth : breakdown of growth rate is immediately obtained, from 7,2 cm to 0,5 cm every year. During all the treatment and after, the complete gain of height will not exceed 1 or 2 cnetimeters over the initial height. Quality of results is better than that of other methods; side effects, if any, are mild and disappear when stopping the treatment.
D000293:Adolescent; D001827:Body Height / Q000187:drug effects*; D005260:Female; D006130:Growth Disorders / Q000188:drug therapy*; D006666:History of Medicine; D006801:Humans; D008297:Male; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use*
D011241:Prednisone
Traitement des excès staturaux chez l'adolescent par une corticothérapie a minima. Démonstration et avantages. A propos de 10 observations traitées par la prednisone