Acute psychotic reaction to procaine penicillin.
A case of a 23-year old black female admitted for treatment of an acute psychotic episode 48 hours after being treated with i.m. procaine penicillin G is reported.  Literature reports of nonallergic psychotic responses to i.m. injections of aqueous procaine penicillin G are reviewed.  Possible mechanisms for the reaction are discussed.  Recommended drugs for treatment of the reaction include phenobarbital and chlorpromazine.
D000328:Adult; D002746:Chlorpromazine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D010402:Penicillin G Procaine / Q000009:adverse effects*; D010595:Pharmacists; D011605:Psychoses, Substance-Induced / Q000188:drug therapy / Q000209:etiology*
D010402:Penicillin G Procaine; D002746:Chlorpromazine