[Dopamine in essential arterial hypertension: excretion of its metabolite homovanillic acid].
The results obtained in a group of 66 hypertensive patients in which the AHV values were 5.7 plus and minus 0.4 mM/24 hrs., were reported. These values were compared to those obtained in 42 healthy subjects: 7.0 plus and minus 0.5 mM/24 hrs. The difference was statistically significant P less than 0.05. The values of excretion of urinary dopamine in both groups were also presented. A value of 225.7 plus and minus 13.0 mug/24 hrs. was obtained for the hypertensives, while the value for the healthy groups was 361.2 plus and minus 16.5. The statistical study in this case showed a high significance p smaller or less than 0.001. There were no changes in the levels of adrenaline and noradrenaline nor in the metabolite of these two amines, that is, AVM.
D000293:Adolescent; D000328:Adult; D004298:Dopamine / Q000378:metabolism* / Q000652:urine; D004837:Epinephrine / Q000652:urine; D005260:Female; D006719:Homovanillic Acid / Q000652:urine*; D006801:Humans; D006973:Hypertension / Q000378:metabolism / Q000652:urine*; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000652:urine; D010648:Phenylacetates / Q000652:urine*; D013997:Time Factors
D010648:Phenylacetates; D004298:Dopamine; D009638:Norepinephrine; D006719:Homovanillic Acid; D004837:Epinephrine
La doamina en la hipertensión arterial esencial: excreción de su metabolito el ácido homovainíllico