Chronic proliferative arthritis of mice induced by Mycoplasma arthritidis: demonstration of a cell-mediated immune response to mycoplasma antigens in vitro.
Lymphocytes taken from mice chronically infected with Mycoplasma arthritidis exhibited a significant blastogenic response as measured by (3H)thymidine uptake when exposed in vitro to M. arthritidis antigens. The lymphocytes taken from 9 of 12 control mice of similar age exhibited an inhibition of (3H)thymidine uptake when exposed to M. arthritidis antigens.
D000818:Animals; D000942:Antigens, Bacterial; D001168:Arthritis / Q000276:immunology* / Q000382:microbiology; D007111:Immunity, Cellular; D008213:Lymphocyte Activation; D051379:Mice; D009174:Mycoplasma / Q000276:immunology*; D009175:Mycoplasma Infections / Q000276:immunology; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D000942:Antigens, Bacterial; D014316:Tritium; D013936:Thymidine