title: Association of HL-A 5 and immune responsiveness in vitro to streptococcal antigens.
abstract: Lymphocytes, from randomly selected individuals having normal immune function, when incubated in vitro with varying concentrations of streptococcal antigens, responded in three ways: (a) response over the entire antigen concentration range, i.e., responders; (b) low response to only the highest antigen concentrations; and (c) no response at any antigen concentration. Frequency distribution analysis of these groups indicated that a significant association occurred between the ability to respond and HL-A 5.
mesh_terms: D000328:Adult; D000368:Aged; D000942:Antigens, Bacterial; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006801:Humans; D007125:Immunogenetics; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology* / Q000378:metabolism; D008875:Middle Aged; D013291:Streptococcus / Q000276:immunology; D013299:Streptodornase and Streptokinase / Q000276:immunology*; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
chemical_list: D000942:Antigens, Bacterial; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D014316:Tritium; D013299:Streptodornase and Streptokinase; D013936:Thymidine