title: Characterization and tissue distribution of 6-O-beta-D-galactopyranosyl myo-inositol in the rat.
abstract: A disaccharide was isolated from rat mammary tissue and determined to be 6-O-beta-galactopyranosyl myo-inositol (6-beta-galactinol) on the basis of combined gas-liquid chromatography-mass spectrometry of the permethylated and peracetylated derivatives as well as previously reported chemical and enzymatic evidence. 6-beta-Galactinol, also found in rat milk, increased during lactation, and on the 18th day represented approximately 17% of the total non-lipid neutral myo-inositol. The sugar was absent in all other rat tissues examined, suggesting a unique association with the process of lactation. This novel galactoside of one human subject on the basis of paper and gas-liquid chromatography.
mesh_terms: D000818:Animals; D002849:Chromatography, Gas; D003126:Colostrum / Q000032:analysis; D004187:Disaccharides / Q000032:analysis* / Q000302:isolation & purification; D005260:Female; D005690:Galactose / Q000032:analysis*; D006801:Humans; D007294:Inositol / Q000032:analysis*; D007774:Lactation; D008321:Mammary Glands, Animal / Q000378:metabolism; D013058:Mass Spectrometry; D008892:Milk / Q000032:analysis; D008895:Milk, Human / Q000032:analysis; D008968:Molecular Conformation; D011247:Pregnancy; D051381:Rats
chemical_list: D004187:Disaccharides; D007294:Inositol; D005690:Galactose