Antigenic changes in cultured murine lymphomas after retransplantation into syngeneic hosts.
When cultured murine lymphomas were retransplanted into syngeneic hosts, the quantitative representation of H-2 antigens and Moloney leukemia virus-determined cell-surface antigens tended to revert to the antigenic pattern characteristic of the corresponding lines propagated in vivo. In some instances, a complete reversion of both the virus-specific and H-2 antigens was observed after a single passage of cultured lymphoma cells in syngeneic hosts.
D000818:Animals; D000937:Antigen-Antibody Reactions; D000951:Antigens, Neoplasm / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis*; D002478:Cells, Cultured; D008223:Lymphoma / Q000276:immunology*; D051379:Mice; D008979:Moloney murine leukemia virus / Q000276:immunology; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000276:immunology; D014184:Transplantation, Homologous
D000951:Antigens, Neoplasm; D000956:Antigens, Viral