Histocompatibility antigens (HL-A) in leprosy.
HL-A antigens of 70 leprosy patients and 40 normal healthy individuals were determined by the standard microlymphocytotoxicity test. Both lepromatous and non-lepromatous leprosy patients were tested for the presence of 11 HL-A antigens, and the frequency of each specificity was compared with that in a normal population of the same ethnic group. Although the statistical significance of HL-A8 specificity was found to be marginal in lepromatous leprosy patients, when using ordinary 2 times 2 statistics, there did seem to be a decreased frequency of HL-A9 among the non-lepromatous type. Other antigens tested did not reveal any significant differences between the two groups of subjects.
D000328:Adult; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006801:Humans; D007106:Immune Sera; D007918:Leprosy / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D010641:Phenotype
D006680:HLA Antigens; D006649:Histocompatibility Antigens; D007106:Immune Sera