Embryonal rhabdomyosarcoma of the bladder and prostate in childhood.
Of 30 children treated for embryonal rhabdomyosarcoma the primary site of tumor was the bladder in 14 cases (9 boys and 5 girls) and the prostate in 16 cases. The mean age at diagnosis was 3 years in patients with bladder sarcoma and 6.5 years in patients with sarcoma of the prostate. Over-all survival rate has been 23 per cent--5 children with rhabdomyosarcoma of the bladder and 2 with rhadbomyosarcoma of the porstate are alive from 1 1/2 to 23 years postoperatively. Aggressive coordinated treatment with surgery, radiotherapy and cyclic combination chemotherapy is recommended.
D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003609:Dactinomycin / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009362:Neoplasm Metastasis; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000628:therapy; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000601:surgery / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000628:therapy; D014547:Urinary Diversion
D003609:Dactinomycin