Properties of plasmids produced by recombination between R factors of groups J and FII.
Recombinant plasmids have been produced both by transduction of genetic material from FIIR factors into Proteus mirabilis strains carrying plasmids of group J and by insertion of a transposon conferring streptomycin and trimethoprim resistances into a J group R factor. The transposon-carrying derivative and one of the transductants were shown to be members of group J whereas another transductant was shown to be compatible with members of this group. This recombinant plasmid was able to eliminate but not to be eliminable by R factors of group FII. A model for the origin of this anomalous compatibility characteristic is presented based on the assumption that the recombinant plasmid carries part but not all of a complex of binding sites for the repressor of replication [Uhlin and Nordström (1975)].
D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D003227:Conjugation, Genetic; D004352:Drug Resistance, Microbial; D005111:Extrachromosomal Inheritance; D010957:Plasmids; D011513:Proteus mirabilis; D011815:R Factors; D011995:Recombination, Genetic; D013307:Streptomycin; D014161:Transduction, Genetic
D013307:Streptomycin