title: [Acinar epithelium as a source for the formation of the human pancreatic islets in embryogeny].
abstract: By electron microscopy in the islets of Largenhans and acini of the pancreas of the human fetuses 4-7 months old acinar-islet (transitional) cells were revealed. The cytoplasm of some transitional elements contained zymogen and endocrine A-granules, while in others zymogen and endocrine B-granules were found. Acinar-islet cells differed by the structure of organelles and by the quantity of endocrine granules, which can be regarded as transformation of acinar cells into endocrine cells. A conclusion was drawn that during human pancreas embryogenesis the acinar epithelium is one of the sources of islet tissue formation.
mesh_terms: D004847:Epithelial Cells; D004848:Epithelium / Q000196:embryology / Q000648:ultrastructure; D005260:Female; D005333:Fetus / Q000648:ultrastructure; D005865:Gestational Age; D006801:Humans; D007515:Islets of Langerhans / Q000196:embryology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D011247:Pregnancy
vernacular_title: Atsinarnyĭ épiteliĭ kak istochnik obrazovaniia pankreaticheskikh ostrovkov podzheludochnoĭ zhelezy cheloveka v émbriogeneze