Changes in distribution pattern of cytoplasmic filaments in human melanocytes during ultraviolet-mediated melanin pigmentation. The role of the 100-Angstrom filaments in the elongation of melanocytic dendrites and in the movement and transfer of melanosomes.
Human melanocytes characteristically contain 100-A filaments. These 100-A filaments shift from the perinuclear area to the center of the dendritic processes and are in close association with melanosomes during the different stages of UV-mediated melanin pigmentation. We suggest that these 100-A filaments in human melanocytes participate in the elongation of the dendrites and in the transfer of melanosomes.
D002081:Buttocks; D003571:Cytochalasin B / Q000494:pharmacology; D003593:Cytoplasm / Q000502:physiology / Q000648:ultrastructure; D003712:Dendrites / Q000648:ultrastructure*; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D005542:Forearm; D006801:Humans; D008543:Melanins / Q000096:biosynthesis*; D008544:Melanocytes / Q000378:metabolism / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008870:Microtubules / Q000648:ultrastructure; D009940:Organoids / Q000648:ultrastructure; D010858:Pigmentation / Q000528:radiation effects; D011830:Radiation Effects; D012867:Skin / Q000648:ultrastructure*; D013997:Time Factors; D014466:Ultraviolet Rays; D014750:Vincristine / Q000494:pharmacology
D008543:Melanins; D003571:Cytochalasin B; D014750:Vincristine