[Optimation of irradiation planning in deep therapy. Outline of the chance of survival of tumor patients].
Simple model conceptions are used for the demonstration of the chance of survival of tumor patients. The systematic judgement of therapy is possible after the adaptation to known survival curves for patients in different stages. The ascertainment of the tumor duplication period for primary tumor and--on principle--also for metastases, permits of conclusions on the recuperative capacity and radioresistance of the exposed normal tissue and of the tumor. It was seen that the values found can lie in the range of the data known from radiobiology. Vice versa, it is possible in principle by means of derived relation to optimate dose distribution, fractionation and total dose of the radiotherapy. Moreover, the systematic analysis of the known survival curves of tumor patients within the frame of model conception allows of the expectation that also influences of therapy on the tumor duplication time, and possibly the dissemination capacity of the tumor, can be analysed. These values reflect the tumor-host-relations and seem to be of decisive significance for future successful concepts of therapy.
D006128:Growth; D006801:Humans; D008433:Mathematics; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy; D011379:Prognosis; D011878:Radiotherapy; D011879:Radiotherapy Dosage; D013997:Time Factors
Zur Optimierung der Bestrahlungsplanung in der Tiefentherapie. Skizzierung der Uberlebenswahrscheinlichhkeit von Tumorpatienten