title: [Isoxazolylpenicillins with cycloaliphatic substituents in the isoxazole ring].
abstract: Some derivatives of oxacillin were prepared containing in place of the phenyl group a cyclohexyl, cyclohexylphenyl, phenylcyclohexyl or diphenylyl moiety. In the same compounds a methylene bridge between the carboxy group and the heterocyclic ring was inserted. The results of in vitro evaluation of antibacterial activity are given.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D008826:Microbial Sensitivity Tests; D010068:Oxacillin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D013291:Streptococcus / Q000187:drug effects
chemical_list: D010068:Oxacillin
vernacular_title: Isossazolilpenicilline con sostituenti cicloalifatici nel nucleo isossazolico