Intubating conditions with AH 8165 and suxamethoniun.
Intubating conditions after AH 8165, 1times25 mg/kg, have been compared with those after suxamethonium 1 mg/kg in 240 patients. Patients were matched for physical fitness and intubating conditions were studied in different groups at 30, 45, 60 and 75 seconds after the relaxant. At all times suxamethonium produced a higher incidence of good relaxation of the vocal cords and the incidence of excellent overall intubating conditions was significantly higher with suxamethonium. It proved impossible to intubate eleven patients with AH 8165 at the chosen time but all patients receiving suxamethonium could be intubated.
D001372:Aza Compounds / Q000494:pharmacology*; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology; D007442:Intubation, Intratracheal; D009132:Muscles / Q000187:drug effects; D009466:Neuromuscular Blocking Agents / Q000494:pharmacology*; D011229:Preanesthetic Medication; D011726:Pyridinium Compounds / Q000494:pharmacology*; D013390:Succinylcholine / Q000494:pharmacology*; D013997:Time Factors; D014827:Vocal Cords / Q000187:drug effects
D001372:Aza Compounds; D007093:Imidazoles; D009466:Neuromuscular Blocking Agents; D011726:Pyridinium Compounds; D013390:Succinylcholine