Lowered serum cholesterol following the ingestion of a hydrophilic colloid.
An attempt was made to test the possible clinical application of the cholesterol-lowering effect of hydrophilic colloids. 10 patients with high mean serum cholesterol levels during a 3-week control period and 9 with normal mean levels were each fed 11.5 g daily of undiluted hydrophilic colloid for 5 weeks. Serum cholesterol decreased significantly in 8 of the 10 (80%) patients with control-period hypercholesteremia and 6 of the 9 (66 2/3%) with control-period normal levels. These findings tend to confirm the observation that a simple and commonly used type of medication for chronic constipation, particularly in the elderly, may be a useful adjunct in the management of hypercholesterolemia.
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood*; D003102:Colloids; D004032:Diet; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011620:Psyllium / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors
D003102:Colloids; D011620:Psyllium; D002784:Cholesterol