title: Microsomal enzyme induction by methadone and its implications on tolerance to methodone lethality.
mesh_terms: D000818:Animals; D001711:Biotransformation; D004361:Drug Tolerance; D004790:Enzyme Induction; D007928:Lethal Dose 50; D008099:Liver / Q000033:anatomy & histology; D008691:Methadone / Q000494:pharmacology* / Q000633:toxicity; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology; D009020:Morphine / Q000633:toxicity; D009929:Organ Size; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology; D011506:Proteins / Q000378:metabolism
chemical_list: D011506:Proteins; D009020:Morphine; D010089:Oxidoreductases, N-Demethylating; D008691:Methadone; D010634:Phenobarbital