title: Thin-layer chromatographic separation of methadone and its primary metabolite in the presence of other drugs in urine specimens.
abstract: Three solvent systems for thin-layer chromatography have been developed for methadone and its primary metabolite (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine). These solvent systems separate methadone and its primary metabolite, and are not interfered by other drugs of abuse in urine specimens.
mesh_terms: D002855:Chromatography, Thin Layer; D006801:Humans; D008691:Methadone / Q000031:analogs & derivatives / Q000378:metabolism / Q000652:urine*; D011759:Pyrrolidines / Q000652:urine; D012997:Solvents; D019966:Substance-Related Disorders
chemical_list: D011759:Pyrrolidines; D012997:Solvents; D008691:Methadone