title: Dynamics of tissue distribution of radiopotassium as affected by simulated differences in regional extraction.
abstract: Simulation of tissue uptake and release of radiopotassium with a digital computer shows that tissue distribution of this diffusible indicator of regional blood flow will be essentially static during recirculation of the isotope despite large differences in regional extractions. Thus, the widely accepted view that static distribution results from homogeneous extractions may be invalid.
mesh_terms: D003201:Computers; D003326:Coronary Circulation; D008954:Models, Biological; D009206:Myocardium / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D011197:Potassium Radioisotopes / Q000378:metabolism*; D011652:Pulmonary Circulation; D011865:Radioisotope Dilution Technique; D012039:Regional Blood Flow
chemical_list: D011197:Potassium Radioisotopes; D011188:Potassium