title: [Effectiveness of treating chronic cholecystitis by prodigiozain electrophoresis].
abstract: 136 patients suffering from chronic cholecystitis were treated in the phase of exacerbation with antibiotics in combination with prodigiosan. It was found that inclusion of prodigiosan into the therapeutic complex had a positive effect on the immediate and late results of the treatment. Since intramuscular administration of prodigiosan was accompanied by a number of side effects, a method of the drug administration by means of electrophoresis on the area of the bile bladder was tested. It was shown that prodigiosan administered by the method of electrophoresis totally preserved its stimulating capacity with respect to the host. As with intramuscular administration of prodigiosan, the general reaction of the host and positive dynamics of the clinical and laboratory indices of the active process were observed and the content of lysozyme in the blood phagocytes reliably increased. The method of prodigiosan administration by means of electrophoresis was better tolerated by the patients and no side effects characteristic of the drug intramuscular administration were noted. When indicated, the use of prodigiosan by means of electrophoresis is recommended.
mesh_terms: D000328:Adult; D002701:Chloramphenicol / Q000627:therapeutic use; D002764:Cholecystitis / Q000188:drug therapy*; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D005260:Female; D005704:Gallbladder; D006801:Humans; D007273:Injections, Intramuscular; D007478:Iontophoresis; D008297:Male; D008875:Middle Aged; D011353:Prodigiosin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D002701:Chloramphenicol; D011353:Prodigiosin
vernacular_title: Ob éffektivnosti lechenii élektroforezom prodigiozana bol'nykh khronicheskim kholetsistitom