Hemoglobin S/C disease in a pregnant woman with crisis and fat embolization syndrome.
The complications of painful crisis and megaloblastic anemia are hallmarks of the pregnant patient with hemoglobin S/C disease. We describe here the clinical course in a patient with hemoglobin S/C disease in whom painful crisis and the fat embolization syndrom developed postpartum with severe neurologic abnormalities. Response to exchange blood transfusion was dramatic, and the patient recovered without neurologic impairment.
D000328:Adult; D000755:Anemia, Sickle Cell / Q000175:diagnosis / Q000628:therapy; D004620:Embolism, Fat / Q000175:diagnosis / Q000628:therapy; D005078:Exchange Transfusion, Whole Blood; D005260:Female; D006445:Hemoglobin C Disease / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010146:Pain / Q000175:diagnosis; D059408:Pain Management; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic; D011644:Puerperal Disorders / Q000175:diagnosis / Q000628:therapy; D013577:Syndrome