On the exudation of plasticizers from PVC haemodialysis tubings.
Prompted by a series of hepatitis-like cases in patients on regular haemodialysis treatment, the sets of polyvinylchloride (PVC) test tubings used were submitted to perfusion experiments. The perfusates from four commercially available tubings were also investigated. Diethylphthalate (DEP) could be identified by by IR and PMR spectrometry in the perfusate from the test tubings. UV spectrometry proved the presence of other non-identified substances in the perfusate from both the test tubings and from some of the other tubings.
D000818:Animals; D056486:Chemical and Drug Induced Liver Injury; D002855:Chromatography, Thin Layer; D004865:Equipment and Supplies, Hospital; D004952:Esters; D006801:Humans; D007688:Kidneys, Artificial; D009682:Magnetic Resonance Spectroscopy; D010477:Perfusion; D010795:Phthalic Acids / Q000009:adverse effects* / Q000032:analysis; D011143:Polyvinyl Chloride / Q000009:adverse effects*; D011522:Protons; D051381:Rats; D006435:Renal Dialysis / Q000009:adverse effects*; D013056:Spectrophotometry, Ultraviolet; D013057:Spectrum Analysis
D004952:Esters; D010795:Phthalic Acids; D011522:Protons; D011143:Polyvinyl Chloride