title: Clinical study of a progesterone-releasing intrauterine contraceptive device.
abstract: A double-blind clinical study was performed to determine whether the release of progesterone from an intrauterine contraceptive device (IUD) had any effect on IUD event rates. A total of 101 women received intrauterine contraceptive devices containing progesterone, resulting in the accumulation of 877 women-months experience; 100 women received IUD's without steroid, resulting in the accumulation of 780 women-months. The only significant difference was a higher incidence of pregnancy in those patients using devices which did not contain progesterone.
mesh_terms: D000328:Adult; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007434:Intrauterine Devices / Q000009:adverse effects*; D010146:Pain; D011247:Pregnancy; D011374:Progesterone / Q000008:administration & dosage*; D014592:Uterine Hemorrhage / Q000209:etiology* / Q000517:prevention & control
chemical_list: D011374:Progesterone