title: Abdominal wound disruption.
abstract: Abdominal wound disruption occurred in 6 cases in a series of 2500 consecutive abdominal laparotomies. A prospective study of 900 laparotomies utilizing polyglycolic acid suture material and the Smead-Jones closure technic was carried out over a period of 1 year with a reduction in the incidence of wound disruption from 0.4 to 0.1%. Etiologic factors placing patients in a high-risk category for disruption are identified, and specific prophylactic measures are discussed. Prevention of catastrophic disruption is advocated because of its high mortality rate, averaging 20%.
mesh_terms: D000328:Adult; D005260:Female; D005831:Genital Diseases, Female / Q000601:surgery; D006801:Humans; D007813:Laparotomy; D008875:Middle Aged; D011100:Polyglycolic Acid; D011183:Postoperative Complications; D011247:Pregnancy; D011248:Pregnancy Complications / Q000601:surgery; D011446:Prospective Studies; D012306:Risk; D013529:Surgical Wound Dehiscence / Q000453:epidemiology* / Q000209:etiology; D013536:Suture Techniques; D013537:Sutures
chemical_list: D011100:Polyglycolic Acid