title: The influence of geometrical factors in 131-I-hippuran renography.
abstract: Using a particular collimated NaI scintillation detector and a kidney phantom containing 131-I, the dependence of the resulting count rates on collimator-kidney geometry has been determined. These results have been used to calculate the geometrical contribution to the error in the measurement of relative effective renal plasma flow (REP) by 131-I-Hippuran renography. When radiographic and ultrasonic methods of localizing the kidneys are employed, this error has been found to follow a normal distribution with a SD of 2.6% in the case of equally divided function. Combination of this error with that from natural movement and statistical fluctuations, as observed using a dose of 10 muCi 131-I-Hippuran, has led to the estimation of a corresponding potential error 11%. Values of the potential error, which is defined as the 99% probability range, have been calculated covering the range of RFP.
mesh_terms: D003951:Diagnostic Errors; D006801:Humans; D007465:Iodohippuric Acid; D007668:Kidney / Q000098:blood supply; D008954:Models, Biological; D008961:Models, Structural; D011866:Radioisotope Renography; D012039:Regional Blood Flow
chemical_list: D007465:Iodohippuric Acid