title: Optimal fluoridation--The concept and its application to municipal water fluoridation.
abstract: Optimal fluoridation has been defined as that fluoride exposure which confers maximal cariostasis with minimal toxicity and its values have been previously determined to be 0.5 to 1 mg per day for infants and 1 to 1.5 mg per day for an average child. Total fluoride ingestion and urine excretion were studied in Marin County, California, children in 1973 before municipal water fluoridation. Results showed fluoride exposure to be higher than anticipated and fulfilled previously accepted criteria for optimal fluoridation. Present and future water fluoridation plans need to be reevaluated in light of total environmental fluoride exposure.
mesh_terms: D000293:Adolescent; D002140:California; D002648:Child; D002675:Child, Preschool; D004032:Diet; D005457:Fluoridation; D005459:Fluorides / Q000032:analysis / Q000652:urine; D005504:Food Analysis; D006801:Humans; D009111:Local Government; D014881:Water Supply
chemical_list: D005459:Fluorides