Pathophysiology of stress ulcer and its prevention. I. Pharmacologic doses of steroid.
The efficacy of a large dose of Decadron on stress ulcer formation in restrained rats has been studied using microangiohistologic technics. When a pharmacologic dose of Decadron was administered twenty-four hours prior to the procedure, Dacadron prevented ulcer formation.
D000818:Animals; D003080:Cold Temperature; D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use*; D004781:Environmental Exposure; D005753:Gastric Mucosa / Q000473:pathology; D008297:Male; D008833:Microcirculation; D051381:Rats; D013270:Stomach / Q000098:blood supply / Q000473:pathology; D013276:Stomach Ulcer / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control; D013312:Stress, Physiological / Q000150:complications*
D003907:Dexamethasone