A 82Sr-82Rb isotope generator for use in nuclear medicine.
An improved 82Sr-82Rb generator system, based on the complexing ion-exchange resin Chelex-100, has been developed. Columns of this material can be easily and rapidly milked, and the rubidium-strontium separation factor for a fresh generator under the experimental conditions studied was found to be greater than 10-7. Approximately 80% of the 82Rb present can be delivered in a 15-ml volume of aqueous 0.2 M NH4Cl solution. After more than 6 liters of eluant had passed through the generator, the rubidium-strontium separation factor was still observed to greater than 10-5 and no unusual strontium breakthrough behavior was seen in the system over nearly three 82Sr half-lives.
D007475:Ion Exchange Resins; D011868:Radioisotopes / Q000302:isolation & purification*; D012413:Rubidium / Q000302:isolation & purification*; D013326:Strontium Radioisotopes
D007475:Ion Exchange Resins; D011868:Radioisotopes; D013326:Strontium Radioisotopes; D012413:Rubidium