Isolation of galantins I and II, water-soluble basic peptides. Studies on antibiotics from the genus Bacillus. III.
Two water-soluble basic antibiotics named galantins I and II were isolated from a strain resembling Bacillus pulvifaciens. Both antibiotics are peptides containing glycine, alanine, ornithine, lysine and some unknown ninhydrin-positive components. An approximate empirical formula C50 plus and minus H98plus and minus 2O17N16 is indicated for galantin I. These are active against some gram-positive, acid-fast and gram-negative bacteria.
D000409:Alanine / Q000032:analysis; D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D001407:Bacillus / Q000032:analysis*; D001419:Bacteria / Q000187:drug effects; D005998:Glycine / Q000032:analysis; D007710:Klebsiella Infections / Q000188:drug therapy; D008239:Lysine / Q000032:analysis; D051379:Mice; D009952:Ornithine / Q000032:analysis; D010455:Peptides / Q000302:isolation & purification* / Q000494:pharmacology; D012995:Solubility
D000900:Anti-Bacterial Agents; D010455:Peptides; D009952:Ornithine; D008239:Lysine; D000409:Alanine; D005998:Glycine