title: [Integration of palmitat-1-14-C in lecithine and phospholipid content in normal and micro-embolized rabbit lungs (author's transl)].
abstract: Glass microspheres were used for a diffuse pulmonary microembolisation, as a modell for shock lung. Microembolisation is regarded as an important factor in pathogenesis of shock lung. The capacity of lung for lecithin synthesis was measured with palmitat-1-14-C incorporation. The phospholipid content and the composition of the fatty acids of lecithin were investigated. From the results it was possible, that the surfactant system may alterated by the vascular blocking. The dates supporting the importance of microembolisation in pathogenesis of shock lung.
mesh_terms: D000818:Animals; D002250:Carbon Radioisotopes; D004247:DNA / Q000378:metabolism; D004195:Disease Models, Animal; D005227:Fatty Acids / Q000378:metabolism; D005260:Female; D005898:Glass; D008168:Lung / Q000378:metabolism*; D008297:Male; D008863:Microspheres; D010169:Palmitic Acids / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000096:biosynthesis* / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D011655:Pulmonary Embolism / Q000150:complications / Q000378:metabolism*; D011817:Rabbits; D012769:Shock; D013499:Surface Properties
chemical_list: D002250:Carbon Radioisotopes; D005227:Fatty Acids; D010169:Palmitic Acids; D010713:Phosphatidylcholines; D010743:Phospholipids; D004247:DNA
vernacular_title: Einbau von Palmitat-1-14-C in Lecithin und Phospholipidgehalt in normalen und mikroembolisierten Kaninchenlungen. Modellstudie zur sogenannten Schocklunge