Observations on the dose regime of fluphenazine decanoate in maintenance therapy ofschizophrenia.
An analysis of the drug regimes prescribed to two separate groups of unselected schizophrenic patients indicates certain trends of clinical importance. The results demonstrate a need for the adoption of a personalized dose regime. The scatter of dose regimes found effective is too great to recommend a standardized approach to the prescription of L.A.P. injections. Two other results of particular significance are that the dose of drug required to control symptoms can be gradually reduced in nearly half of patients,and that helpful trends in prescribing were identified that will help the clinician to abolish side-effects.
D000328:Adult; D003692:Delayed-Action Preparations; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005476:Fluphenazine / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D006760:Hospitalization; D006778:Hospitals, Psychiatric; D006801:Humans; D007267:Injections; D007902:Length of Stay; D008875:Middle Aged; D010044:Outpatient Clinics, Hospital; D012008:Recurrence; D012559:Schizophrenia / Q000188:drug therapy*; D013997:Time Factors
D003692:Delayed-Action Preparations; D005476:Fluphenazine