title: Effect of acute infection and endotoxemia on zinc absorption in the rat.
abstract: Intestinal zinc absorption was found to be significantly increased during acute bacterial infection and endotoxemia in the rat. Although serum zinc concentrations were depressed, there was a significant accumulation of 65Zn in the livers of the stressed animals. This study demonstrates that acute inflammation produces a redistribution of zinc within the host, which results in both increased zinc absorption and retention.
mesh_terms: D000818:Animals; D004731:Endotoxins / Q000494:pharmacology; D004926:Escherichia coli; D007249:Inflammation / Q000139:chemically induced / Q000378:metabolism*; D007408:Intestinal Absorption; D008099:Liver / Q000378:metabolism; D008297:Male; D051381:Rats; D014406:Tularemia / Q000378:metabolism*; D015032:Zinc / Q000097:blood / Q000378:metabolism*
chemical_list: D004731:Endotoxins; D015032:Zinc