Viral labyrinthitis -- an experimental study.
Summary--An attempt was made to produce viral labyrinthitis in the rhesus monkey. Rhesus monkeys are susceptible to the mumps virus. Nine animals were used. After removal of the stapes, the left oval windows were plugged with Gelfoam soaked in a culture of live mumps virus; right oval windows were plugged with Gelfoam soaked in killed cultures. Animals were sacrificed at different time intervals, postinfection. In eight of the nine animals there was seroconversion from negative to positive; however, none of the animals developed the histologic changes of viral labyrinthitis.
D000818:Animals; D046508:Culture Techniques; D003638:Deafness / Q000209:etiology / Q000382:microbiology; D007758:Ear, Inner / Q000382:microbiology / Q000473:pathology; D007249:Inflammation / Q000209:etiology / Q000473:pathology; D007759:Labyrinth Diseases / Q000150:complications / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D008253:Macaca mulatta; D009107:Mumps / Q000150:complications*; D009109:Mumps virus; D013701:Temporal Bone / Q000473:pathology