[Correlation of the antibody concentrations in the cells, subcellular structures and blood serum of rabbits immunized with cholera vaccine].
Experiments were conducted on animals. Following immunization with cholera vaccine there were revealed vibriocidal antibodies, sometimes -- agglutinating, but no vibriolysins in the cells of the mucosal epithelium of the small intestine, of the liver, the spleen and in the fractions obtained from the cells with the aid of differential centrifugation. This corresponds to the high titre of vibriocidal antibodies in the serum and a relatively low titre of the other types of antibodies. In parenteral immunization with various doses of cholera vaccine the concentration of vibriocidal antibodies reached 10(1)-10(7) per 1 mg of protein, which was millions of times less than in the blood serum.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis*; D002477:Cells / Q000276:immunology; D022121:Cholera Vaccines / Q000008:administration & dosage*; D004847:Epithelial Cells; D004848:Epithelium / Q000276:immunology; D005455:Fluorescent Antibody Technique; D007114:Immunization; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D007413:Intestinal Mucosa / Q000276:immunology; D008099:Liver / Q000276:immunology; D011817:Rabbits; D013154:Spleen / Q000276:immunology; D013347:Subcellular Fractions / Q000276:immunology*
D000907:Antibodies, Bacterial; D022121:Cholera Vaccines
O sootnoshenii kontsentratsiĭ antitel v kletkakh, subkletochnykh strukturakh i syvorotke krovi krolikov, immunizirovannykh kholernoĭ vaktsinoĭ