title: [Investigations on the Heredity of the Nephrotic Syndrome (author's transl)].
abstract: The familial nephrotic syndrome has a frequency of 3%. There are 2  types of manifestation. A malignant form with probably autosomal recessive inheritance and bad prognosis, and a benign form with the histology of mimal change disease, complete recovery and a multifactorial inheritance. According to the literature and our own calculations there is in the BRD a yearly frequency of 9--14.4 families with a familial nephrotic syndrome, based on the assumption of 300--480 new cases of nephrotic syndrome per year.
mesh_terms: D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D005860:Germany, West; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics* / Q000473:pathology; D011379:Prognosis; D011507:Proteinuria / Q000235:genetics
vernacular_title: Untersuchungen zur Familiarität des nephrotischen Syndroms