title: Technique for accurately producing desired carboxyhemoglobin levels during rest and exercise.
abstract: A method is described for accurately adjusting a subject's blood carboxyhemoglobin (HbCO) level and then maintaining this level during either rest or exercise. The data presented describe the constancy with which HbCO levels (between 3 and 5% HbCO)were maintained despite varying the inspired ventilatory volumes from 5 to 120 1/min (BTPS). After an initial bolus inhalation of CO to bring the blood HbCO to a desired level, the concentration of CO in the inspired air to maintain this level of HbCO can be predicted from the following equation: COI (ppm) = desired %HbCO divided by 0.180.
mesh_terms: D001822:Body Burden; D002248:Carbon Monoxide / Q000097:blood*; D002263:Carboxyhemoglobin; D006454:Hemoglobins; D006801:Humans; D010101:Oxygen Consumption; D010313:Partial Pressure; D005082:Physical Exertion; D010827:Physiology / Q000379:methods*
chemical_list: D006454:Hemoglobins; D002248:Carbon Monoxide; D002263:Carboxyhemoglobin