Oxidative phosphorylation in the skeletal muscles of rabbits during dinithrophenol hyperthermia.
After intramuscular injection of 2,4-dinitrophenol (DNP) into rabbits in doses of 10,15, 25, and 30 mg/kg the degree of elevation of the body temperature, the phosphorylation in skeletal muscle homogenates were found o increase with the dose. In the course of dinitrophenol hyperthermia (following injection of 25 mg/kg DNP) the changes in body temperature and oxygen consumption of the animals followed a parallel course with the changes in the level of oxidative phosphorylation in the skeletal muscles.
D000818:Animals; D001831:Body Temperature; D004140:Dinitrophenols; D005334:Fever / Q000139:chemically induced / Q000378:metabolism*; D066298:In Vitro Techniques; D009132:Muscles / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption; D011817:Rabbits
D004140:Dinitrophenols