Leber's miliary aneurysms associated with telangiectasia of the nasal mucosa.
A 20-year-old woman, treated with cryopexy and xenon- and argon-laser photocoagulation for Leber's miliary aneurysms in her right eye, suffered from repeated epistaxis. She underwent an endoscopy that showed an unusual number of telangiectatic veins. Laboratory results and routine physical and neurologic examinations showed normal values. Dematologic examination revealed no signs of hereditary hemorrhagic telangiectasis (Osler's disease). Nevertheless, it seems reasonable to assume that the combination of microvascular disturbances in one eye and in the nasal mucous membrane is not a coincidental finding.
D000328:Adult; D000783:Aneurysm / Q000150:complications*; D002196:Capillaries; D004844:Epistaxis / Q000209:etiology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D009297:Nasal Mucosa / Q000098:blood supply* / Q000473:pathology; D012166:Retinal Hemorrhage / Q000209:etiology; D012171:Retinal Vessels; D013684:Telangiectasis / Q000150:complications* / Q000473:pathology; D014792:Visual Acuity