Antiovulatory activity of synthetic corticoids.
A single dose of triamcinolone acetonide had antiovulatory properties in 7 of 11 women when injected on day 1 or 2 of the menstrual cycle. Daily blood studies in three subjects revealed that the FSH and LH surges were absent, and there was no rise in plasma progesterone. Follicular function, as manifested by estrogen levels, was maintained.
D000328:Adult; D004967:Estrogens / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D010060:Ovulation / Q000187:drug effects*; D011374:Progesterone / Q000097:blood; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000494:pharmacology*
D004967:Estrogens; D011374:Progesterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D014222:Triamcinolone Acetonide; D006854:Hydrocortisone