Heterogeneous elevation of amino acid transport rates in pantothenate-and lipid-deficient Lactobacillus plantarum.
The effect of a pantothenic acid deficiency in Lactobacillus plantarum on the initial rate of amino acid transport was investigated. Although the steady-state accumulation capacity for all amino acids was markedly reduced in pantothenate-deficient cells, initial rates of uptake either were not changed (asparagine, alanine, lysine) or were increased (glutamic acid, aspartic acid leucine). The findings suggest that a reduction in membrane lipid content heterogeneously affects the operation and/or synthesis of amino acid transport catalysts.
D000596:Amino Acids / Q000494:pharmacology*; D001216:Asparagine / Q000378:metabolism; D001692:Biological Transport; D005971:Glutamates / Q000378:metabolism; D007700:Kinetics; D007778:Lactobacillus / Q000187:drug effects / Q000378:metabolism*; D008055:Lipids / Q000494:pharmacology*; D010205:Pantothenic Acid / Q000494:pharmacology*
D000596:Amino Acids; D005971:Glutamates; D008055:Lipids; D010205:Pantothenic Acid; D001216:Asparagine