Studies on marine microorganisms. IV. A new antibiotic SS-228 Y produced by Chainia isolated from shallow sea mud.
A new antibiotic named SS-228 Y, which inhibits growth of Gram-positive bacteria, Ehrlich carcinoma in mice, and dopamine-beta-hydroxylase, was obtained from a species of Chainia isolated from shallow sea mud in Sagami Bay. It was yellowish brown powder having the molecular formula C19H1406. From the physical and chemical properties, SS-228 Y was concluded to b a new antibiotic having structure of peri-hydroxyquinone moiety.
D000192:Actinomycetales / Q000378:metabolism*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000302:isolation & purification* / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000032:analysis; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy; D002473:Cell Wall / Q000032:analysis; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003470:Culture Media; D051379:Mice; D012623:Seawater; D012987:Soil / Q000032:analysis; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013210:Staphylococcus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D003470:Culture Media; D012987:Soil