title: Cardiovascular malformations with lithium use during pregnancy.
abstract: The 143 cases of lithium use during pregnancy collected by the Register of Lithium Babies show that infants exposed to lithium appear to have a higher than expected ratio of cardiovascular anomalies to all anomalies and may have an increased risk of congenital heart disease. The authors believe that these findings justify a conservative policy on the use of lithium with fertile and pregnant women.
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000453:epidemiology*; D000328:Adult; D001017:Aortic Coarctation / Q000139:chemically induced; D001714:Bipolar Disorder / Q000188:drug therapy*; D002170:Canada; D002254:Carbonates; D002535:Cerebral Aqueduct / Q000002:abnormalities; D003718:Denmark; D004374:Ductus Arteriosus, Patent / Q000139:chemically induced; D004431:Ear, External / Q000002:abnormalities; D004437:Ebstein Anomaly / Q000139:chemically induced; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006330:Heart Defects, Congenital / Q000139:chemically induced*; D006345:Heart Septal Defects, Ventricular / Q000139:chemically induced; D006352:Heart Ventricles / Q000002:abnormalities; D006801:Humans; D007231:Infant, Newborn; D008094:Lithium / Q000009:adverse effects* / Q000627:therapeutic use; D008943:Mitral Valve / Q000002:abnormalities; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D014188:Transposition of Great Vessels / Q000139:chemically induced; D014261:Tricuspid Valve / Q000002:abnormalities; D014481:United States; D014683:Vena Cava, Superior / Q000002:abnormalities
chemical_list: D002254:Carbonates; D008094:Lithium