Aging and ovarian delta5-3beta-hydroxysteroid dehyrogenase in rats.
Ovarian delta5-3beta-hydroxysteroid dehydrogenase activiety and protein content were determined in long-evans rate 1-24 mo of age.  Activity of the enzyme per miligram of protein was maximal between 2 and gram of protein was maximal between 2 and 4 mo of age and declined theragter.  Ovarian enzyme activity of the 24-mo old rat was significantly less than that of the prepubertal animal.  Total ovarian enzyme acitivity was maximal in 4-mo old rats.  A decline in ovarian protein was noted between 4 and 24 mo of age.
D000375:Aging; D000735:Androstenedione / Q000032:analysis; D000818:Animals; D005260:Female; D006913:Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D009929:Organ Size; D010053:Ovary / Q000033:anatomy & histology / Q000201:enzymology / Q000502:physiology; D014176:Protein Biosynthesis; D011506:Proteins / Q000032:analysis; D051381:Rats
D011506:Proteins; D000735:Androstenedione; D006913:Hydroxysteroid Dehydrogenases