Effect of polyunsaturated fatty acids on skin allograft survival and primary and secondary cytotoxic response in mice.
Primary and secondary cell-mediated immune responses are inhibited in vitro and in vivo by polyunsaturated fatty acids, which may have an immune regulatory function in the organism.
D000818:Animals; D001095:Arachidonic Acids / Q000494:pharmacology; D003601:Cytotoxicity Tests, Immunologic; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology*; D006084:Graft Rejection; D007111:Immunity, Cellular / Q000187:drug effects*; D007114:Immunization; D008041:Linoleic Acids / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D016038:Skin Transplantation; D013997:Time Factors; D014184:Transplantation, Homologous
D001095:Arachidonic Acids; D005231:Fatty Acids, Unsaturated; D008041:Linoleic Acids