Isolation, characterization, and amino acid sequence of melanotropins from camel pituitary glands.
The isolation of two beta-melanotropins and two alpha-melanotropins from camel pituitary glands has been described, and their amino acid sequences have been determined. Two of them are identified as alpha-melanotropin and deacetylated alpha-melanotropin. There are also two beta-melanotropins whose structures are identical with the bovine hormone except that one has glycine in position 2 and the other glycine in position 2 as well as glutamine in position 8. The melanocyte-stimulating and lipolytic activities of these four camel melanotropins have been investigated by in vitro assay procedures.
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001001:Anura; D001681:Biological Assay; D002162:Camelus; D002417:Cattle; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D004590:Electrophoresis, Paper; D007931:Leucyl Aminopeptidase; D009074:Melanocyte-Stimulating Hormones / Q000302:isolation & purification / Q000494:pharmacology; D010902:Pituitary Gland / Q000032:analysis*; D012867:Skin / Q000187:drug effects; D013045:Species Specificity; D014357:Trypsin
D000596:Amino Acids; D009074:Melanocyte-Stimulating Hormones; D007931:Leucyl Aminopeptidase; D014357:Trypsin