Disturbance of the urodynamics of the upper urinary tract as a result of hormonal imbalance.
Considerable functional disturbances of the urodynamics, consisting of hypotonia, hypokinesia, and dyskinesia of the pelvis and upper third of the ureters were detected by television excretory pyeloscopy and motion-picture urography in female rabbits after prolonged administration of progesterone and estradiol dipropionate. These findings suggest a role of hormonal imbalance in the pathogenesis of disorders of the urodynamics that are the possible causes of development of pyelonephritis, nephrolithiasis, hydronephrosis, and other diseases of the kidneys in women.
D000818:Animals; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D007668:Kidney / Q000187:drug effects; D007682:Kidney Pelvis / Q000187:drug effects; D011374:Progesterone / Q000494:pharmacology*; D011817:Rabbits; D014513:Ureter / Q000187:drug effects; D014551:Urinary Tract / Q000187:drug effects*; D014554:Urination / Q000187:drug effects; D014567:Urography
D011374:Progesterone; D004958:Estradiol