title: [Lactic dehydrogenase isoenzymes (LDH) in the serum of patients with progressive muscular dystrophy].
abstract: Using agar-gel electrophoresis a highly statistically significant decrease in the fractions LDH-4 and LDH-5 and a rise in the LDH-1 and LDH-2 fractions were demonstrated in the serum of patients with dystrophy. Analogous shifts in LDH isoenzyme pattern were found in the serum of 80% of mothers confirmed carriers of the dystrophy gene.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004796:Clinical Enzyme Tests; D003937:Diagnosis, Differential; D004586:Electrophoresis; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000201:enzymology; D009136:Muscular Dystrophies / Q000175:diagnosis* / Q000235:genetics
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
vernacular_title: Zachowanie sie izoenzymów dehydrogenazy mleczanowej (LDH) w surowicy krwi chorych z postepujaca dystrofia mieśniowa (PDM)