title: A freeze-fracture study of the junctions between glomerular epithelial cells in aminonucleoside nephrosis.
abstract: In rats with aminonucleoside nephrosis, glomerular slit pores are mostly replaced by sites of close apposition between adjacent epithelial cell membranes. In replicas of freeze-fractured glomeruli, such junctions showed incomplete fibrils or grooves typical of "leaky" zonulae occludentes.
mesh_terms: D000818:Animals; D001485:Basement Membrane / Q000648:ultrastructure; D002196:Capillaries / Q000648:ultrastructure; D002462:Cell Membrane / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D004727:Endothelium / Q000648:ultrastructure; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D005614:Freeze Fracturing; D007365:Intercellular Junctions / Q000648:ultrastructure*; D007678:Kidney Glomerulus / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D009401:Nephrosis / Q000139:chemically induced / Q000150:complications / Q000473:pathology*; D011507:Proteinuria / Q000209:etiology; D011691:Puromycin; D051381:Rats
chemical_list: D011691:Puromycin