title: [Contribution to the aetiology of "reversible hepatic dysfunction" (Stauffer's syndrome) associated with renal tumours].
abstract: Biochemical changes, especially isolated rise in alkaline phosphatase and increased thromboplastin time, which have been described as "reversible hepatic dysfunction" (Stauffer's syndrome) were found in a 47-year-old patient with hypernephroma and hepatomegaly without liver metastases at post-mortem examination. The alkaline phosphatase could not be distinguished from the placental isoenzyme (Regan's enzyme). Increased thromboplastin time was due to circulating fibrinogen degradation products.
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000201:enzymology; D000469:Alkaline Phosphatase / Q000097:blood; D001780:Blood Coagulation Tests; D005260:Female; D006529:Hepatomegaly / Q000209:etiology; D006801:Humans; D007527:Isoenzymes; D007680:Kidney Neoplasms / Q000150:complications* / Q000201:enzymology; D008107:Liver Diseases / Q000201:enzymology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010920:Placenta / Q000201:enzymology; D011247:Pregnancy
chemical_list: D007527:Isoenzymes; D000469:Alkaline Phosphatase
vernacular_title: Beitrag zur Atiologie der "reversiblen hepatischen Dysfunktion" (Stauffer-Syndrom) bei Nierentumoren