A comparative study of two dicyclomine preparations in functional bowel disorders.
Using a double-blind crossover technique in patients suffering from maladies associated with gastrointestinal spasm, sustained-release 40 mg dicyclomine hydrochloride tablets (Merbentyl Dospan) have been compared with 20 mg plain dicyclomine hydrochloride tablets (Merbentyl). It has been concluded that these two dicyclomine formulations are equivalent in terms of efficacy and low incidence of side effects.
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D003109:Colonic Diseases, Functional / Q000188:drug therapy; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D003692:Delayed-Action Preparations; D004025:Dicyclomine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004239:Diverticulitis, Colonic / Q000188:drug therapy; D005260:Female; D005767:Gastrointestinal Diseases / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010352:Patient Dropouts; D010919:Placebos
D003509:Cyclohexanecarboxylic Acids; D003692:Delayed-Action Preparations; D010919:Placebos; D004025:Dicyclomine