Randomized trial of transfer factor treatment of human warts.
Dialysed transfer factor, prepared from the leucocytes of a donor whose warts had undergone recent spontaneous regression, was used in the treatment of a child with the Wiskott--Aldrich syndrome. The child then had a spontaneous regression at multiple warty areas. A similar relationship was seen in four otherwise healthy patients in a pilot study. A randomized double-blind study of thirty patients failed to confirm a causal relationship between the transfer factor therapy (equivalent to 2-1 X 10(8) leucocytes) and wart regressions. The need for randomized trials of transfer factor therapy for diseases with a variable natural history is emphasized.
D000293:Adolescent; D000328:Adult; D002648:Child; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D010919:Placebos; D014165:Transfer Factor / Q000627:therapeutic use*; D014860:Warts / Q000628:therapy*; D014923:Wiskott-Aldrich Syndrome / Q000628:therapy
D010919:Placebos; D014165:Transfer Factor