title: Orally given indomethacin and blood flow response to UVL.
abstract: Blood flow in normal skin and skin treated with ultraviolet light (UVL) has been determined by measuring the clearance of epicutaneously applied xenon 133 gas. Mean blood flow in UVL-irradiated skin was 25.7 ml/100 gm/min, which is about twice that found in normal skin (12.2 ml/100 gm/min). Orally administered indomethacin reduced by one third the increase in blood flow produced by UVL irradiation.
mesh_terms: D001775:Blood Circulation / Q000187:drug effects / Q000528:radiation effects*; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage* / Q000494:pharmacology; D010919:Placebos; D011868:Radioisotopes; D012039:Regional Blood Flow / Q000187:drug effects / Q000528:radiation effects; D012867:Skin / Q000098:blood supply*; D014466:Ultraviolet Rays; D014978:Xenon
chemical_list: D010919:Placebos; D011868:Radioisotopes; D014978:Xenon; D007213:Indomethacin