title: The use of mouse protection tests in the diagnosis of caseous lymphadenitis in sheep.
abstract: Mouse protection tests gave promising results in the diagnosis of caseous lymphadenitis in sheep especially those presenting no external lesions. The test was specific since sera of infected sheep were capable of neutralising Corynebacterium ovis toxin while sera of healthy sheep failed to do so. Better results were obtained with 1-0 ml than 0-5 or 0-25 ml serum of infected sheep to neutralise 2 MLD of the toxin through mice.
mesh_terms: D000818:Animals; D003354:Corynebacterium Infections / Q000175:diagnosis / Q000276:immunology / Q000662:veterinary*; D007106:Immune Sera / Q000008:administration & dosage; D007274:Injections, Intraperitoneal; D008199:Lymphadenitis / Q000175:diagnosis / Q000276:immunology / Q000662:veterinary*; D008722:Methods; D051379:Mice; D012756:Sheep; D012757:Sheep Diseases / Q000175:diagnosis* / Q000276:immunology; D014118:Toxins, Biological / Q000008:administration & dosage / Q000302:isolation & purification
chemical_list: D007106:Immune Sera; D014118:Toxins, Biological