A modification of the jump-flinch technique for measuring pain sensitivity in rats.
The jump-flinch procedure provides a sensivite alternative to the hot-plate and tail-flick procedures. Analysis of the components of motor responses to increasing intensity of foot shock presentation has allowed the observational discrimination of five reliably elicited categories of unlearned responses to inescapable foot shock. Morphine sulfate differentially altered response category thresholds in rats. Response category thresholds also differed between Wistar and Fisher strain rats in analgesic effects of morphine sulfate.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D004597:Electroshock; D005069:Evaluation Studies as Topic; D008297:Male; D008722:Methods; D009020:Morphine / Q000494:pharmacology; D010146:Pain; D051381:Rats; D013045:Species Specificity
D009020:Morphine