Investigation of the ultrastructure of DNA-synthesizing cells of a focus of aseptic inflammation.
The ultrastructure of cells of a focus of aseptic inflammation, synthesizing DNA (incorporating H3-thymidine) was studied with the aid of a combination of methods of light autoradiography and plane-parallel embedding. It was shown that these cells have the ultrastructure specific for collagen-synthesizing cells (fibroblasts): a well-developed granular endoplasmic reticulum with a large number of polyribosomes, an extensive Golgi complex, a characteristic structure of the mitochondria, and a large number of cytoplasmic microfibers. Collagen fibers are detected on the surface of the cells.
D000818:Animals; D001345:Autoradiography; D004247:DNA / Q000096:biosynthesis*; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D007249:Inflammation / Q000473:pathology*; D051379:Mice; D008854:Microscopy, Electron; D008928:Mitochondria / Q000648:ultrastructure; D008938:Mitosis; D012270:Ribosomes / Q000648:ultrastructure; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D014316:Tritium; D004247:DNA; D013936:Thymidine