Quantitative evaluation of the maternal-fetal transfer of free fatty acids in the rat.
On the 21st day of pregnancy the amount of fatty acids transferred from the mother to the fetuses was determined using the tracer technique and a mathematical model. The present study showed that 0.19 mu-mol fatty acids/min pass into the fetuses from the maternal circulation. The amount of fatty acids required for the growth and development of the rat fetuses amounts to 0.25 mu-mol fatty acids/min. From these data one can conclude that the maternal circulation is an even more important source of fetal fatty acids than the fatty acid synthesis in fetal tissue.
D000818:Animals; D005230:Fatty Acids, Nonesterified / Q000378:metabolism*; D005260:Female; D008431:Maternal-Fetal Exchange; D008954:Models, Biological; D011247:Pregnancy; D051381:Rats; D013997:Time Factors
D005230:Fatty Acids, Nonesterified