BCG inhibition of murine leudemia: local suppression and systemic tumor immunity require different doses.
The quantitative relationship between bacillus Calmette-Guérin (BCG) and tumor cells which are optimal for suppressing the growth of tumor cells in BCG-tumor cell mixtures are detrimental to the development of a sustained, systemic tumor rejection immunity in the LSTRA murine leukemia.
D000276:Adjuvants, Immunologic; D000818:Animals; D001500:BCG Vaccine; D007114:Immunization; D007942:Leukemia, Experimental / Q000276:immunology* / Q000517:prevention & control; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009163:Mycobacterium bovis / Q000276:immunology*; D009368:Neoplasm Transplantation
D000276:Adjuvants, Immunologic; D001500:BCG Vaccine