title: Hypothalamic dysfunction and intracranial arterial spasms.
abstract: Evidence is presented that suggests that dysfunction of the hypothalamus is an important step in the development of the intracranial arterial spasm that accompanies subarachnoid hemorrhage and craniocerebral trauma. Speculation is offered as to the possible pathogenetic mechanisms involved.
mesh_terms: D000818:Animals; D002415:Cats; D006259:Craniocerebral Trauma / Q000473:pathology; D004285:Dogs; D006801:Humans; D007031:Hypothalamus / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology*; D007511:Ischemia / Q000150:complications; D002546:Ischemic Attack, Transient / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D009638:Norepinephrine; D010673:Pheochromocytoma / Q000150:complications; D011183:Postoperative Complications; D012422:Rupture, Spontaneous; D013345:Subarachnoid Hemorrhage / Q000150:complications / Q000503:physiopathology; D014020:Tissue Extracts; D014666:Vasomotor System / Q000503:physiopathology
chemical_list: D014020:Tissue Extracts; D009638:Norepinephrine