[Study of the population makeup and antibiotic and transamidinase activity of Actinomyces streptomycini 773 stored for a long period in a lyophilized, dried state].
Studies on variation of the streptomycin-producing organism Act. streptomycini 773 on its storage in lyophilized state showed that prolonged maintenance (for 8 years) resulted in increased percentage of "oligospore" (up to 6.9 per cent) and asporogenic (up to 6.0 per cent) variants in the population. The variants had lower transamidinase and antibiotic activity.
D000190:Actinomyces / Q000378:metabolism*; D000579:Amidinotransferases / Q000378:metabolism*; D001407:Bacillus; D003124:Colorimetry; D003470:Culture Media; D005612:Freeze Drying; D014644:Genetic Variation; D008826:Microbial Sensitivity Tests; D011309:Preservation, Biological; D013171:Spores, Bacterial; D013307:Streptomycin / Q000096:biosynthesis*; D013997:Time Factors
D003470:Culture Media; D000579:Amidinotransferases; D013307:Streptomycin
Izuchenie sostava populiatsii, antibioticheskoĭ i transmidinaznoĭ aktivnosti Actinomyces streptomycini 773 pri dlitel'nom khranenii v liofil'no vysushennom sostoianii