The effects of tubal ligation on ovum transport in rabbits.
Ovum transport was studied in rabbit oviducts ligated 18 hr after mating in untreated and oestrogen-treated rabbits. Essentially all ova (93.5%) were recovered from the sham-ligated oviducts averaged 46.7%. Recovery of ova in oviducts ligated at the infundibulum and at the uterotubal junction was 100%. It is likely, therefore, that ova were transported prematurely into the uterus from ligated oviducts. Ovum transport through sham-ligated oviducts was significantly retarded by a single injection of oestradiol cyclopentylpropionate (25 or 250 mug) but remained accelerated in ligated oviducts diminished by 60 hr p.c. in untreated rabbits, but was maintained in oestrogen-treated rabbits. Ovum transport through distended oviducts may be accelerated by the passage of oviducal fluid into the uterus.
D000818:Animals; D004958:Estradiol / Q000008:administration & dosage / Q000494:pharmacology; D004967:Estrogens / Q000008:administration & dosage / Q000494:pharmacology; D005187:Fallopian Tubes / Q000502:physiology*; D005260:Female; D007279:Injections, Subcutaneous; D008026:Ligation; D010057:Oviducts / Q000187:drug effects; D010063:Ovum / Q000502:physiology*; D011247:Pregnancy; D011817:Rabbits; D013997:Time Factors; D014599:Uterus / Q000502:physiology
D004967:Estrogens; D004958:Estradiol