title: Rapid hCG-specific radioimmunoassay for menstrual aspiration.
abstract: Fifty-one women with missed periods ranging from 5 to 14 days who suspected a pregnancy underwent an aspiration curettage with a flexible soft-tipped cannula attached to a Karman-type syringe. Sera from these women were measured for human chorionic gonadotropin (hCG) by a rapid 2-hour solid phase radioimmunoassay using an antibody with a specificity for the beta subunit of hCG. The sensitivity and specificity of this assay insured detection of bCG with 100% accuracy at the time of the missed period. Of the 51 women, 33 (64.7%) were found to have hCG in their serum, and 29 (56.8%) had histologic evidence diagnostic of pregnancy.
mesh_terms: D000028:Abortion, Induced; D006063:Chorionic Gonadotropin / Q000097:blood*; D004107:Dilatation and Curettage; D005260:Female; D006801:Humans; D008598:Menstruation; D011247:Pregnancy; D011258:Pregnancy Tests; D011863:Radioimmunoassay; D013997:Time Factors; D014619:Vacuum Curettage
chemical_list: D006063:Chorionic Gonadotropin