title: Effect of age on epithelial cell migration in small intestine of chickens.
abstract: Villous length, crypt depth, epithelial cell migration rate, and replacement time were studied by autoradiography of histologic sections of small intestine from normal chickens exposed to tritiated thymidine (3-H-TdR). The results indicated that villi and crypts elongate, and epithelial cell migration accelerates between 1 day and 6 months of age. Epithelial replacement time seemed to increase with age of the chickens. Replacement was nearly complete in the 1-day-old group of chickens 5 days after thymidine exposure. In contrast, at this same time, replacement was only approximately 75 and 50% complete in the 3-week-old and 6-month-old groups of chickens, respectively.
mesh_terms: D000367:Age Factors; D000818:Animals; D001345:Autoradiography; D002465:Cell Movement; D002645:Chickens / Q000033:anatomy & histology*; D004386:Duodenum / Q000166:cytology; D004847:Epithelial Cells; D005260:Female; D007082:Ileum / Q000166:cytology; D007421:Intestine, Small / Q000166:cytology*; D007583:Jejunum / Q000166:cytology; D008297:Male