title: [The dynamics of changes in the concentration of luteinizing hormone in the pituitary and the blood during postnatal development of male rats].
abstract: The authors describe a specific and sensitive biological method of determination of luteinizing hormone (LH).  There was shown a linear relationship between the LH dose gradient and the amount of testosterone determined in the blood flowing from the testes.  Sensitivity of the method--5 nanogram/ml.  Linear dependence--5--45 nanogram/ml.  Dynamics of the changes in the LH concentration in the hypophysis and the blood of male rats in the course of postnatal development--from the 1st to the 43rd day was studied.  There were distinguished 6 peaks of increase in the LH content in the hypophysis: on the 4th, 7th, 19th, 27th, 37th and the 43rd day after birth; blood LH concentration persisted at a relatively constant level--within the range of 1.33--4.39 gamma per cent.  No LH was revealed in the blood on the 4th, 19th, and 24th days after birth.
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D001681:Biological Assay / Q000379:methods; D007986:Luteinizing Hormone / Q000032:analysis* / Q000097:blood; D008297:Male; D010902:Pituitary Gland / Q000032:analysis*; D051381:Rats
chemical_list: D007986:Luteinizing Hormone
vernacular_title: Dinamika izmeneniia soderzhaniia liuteiniziruiushchego gormona v gipofize i krovi v khode postnatal'nogo razvitiia u samtsov krys