[Bleeding in haemophilia during massive treatment with anti-haemophilic globulin (author's transl)].
After a traffic accident, causing intracranial haemorrhage in a 15-year-old boy with moderately severe haemophilia A, severe bleeding sequelae could not be prevented despite satisfactory substitution with lyophilized antihaemophilic globulin. The bleeding was probably due to a platelet abnormality and not due to an inhibitor. The bleedings were brought under control by freshly prepared cryoprecipitate of the patient's own blood group.
D000063:Accidents, Traffic; D000293:Adolescent; D001792:Blood Platelets; D001803:Blood Transfusion; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000628:therapy; D005169:Factor VIII / Q000627:therapeutic use*; D006467:Hemophilia A / Q000150:complications* / Q000188:drug therapy; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D008297:Male
D005169:Factor VIII
Blutung bei Hämophilie unter massiver Therapie mit antihämophilem Globulin