[Effects of a unique dose of mebendazole on microfilaremia in 50 carriers of microfilaria of Wuchereria bancrofti, pacifica variety].
Treatment by Mebendazol were given to 50 patients divided in 3 groups, the first on having s single dose of 200 mg., the second one a single dose of 300 mg. and the last one a single dose of 400 mg. There was practically no unpleasant side effect. We noticed a delayed but notable effect on microfilaremia sensibly lower than diethylcarbamazine action in similar conditions. It would be interesting to try heavier doses or iterative doses.
D001562:Benzimidazoles / Q000008:administration & dosage*; D004049:Diethylcarbamazine / Q000627:therapeutic use; D005260:Female; D005368:Filariasis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008463:Mebendazole / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D008842:Microfilariae / Q000187:drug effects; D014957:Wuchereria / Q000187:drug effects*; D014958:Wuchereria bancrofti / Q000187:drug effects
D001562:Benzimidazoles; D008463:Mebendazole; D004049:Diethylcarbamazine
Effets d'une dose unique de mébendazole sur la microfilarémie de 50 porteurs de microfilaires de Wuchereria bancrofti, variété pacifica