title: Basement membrane thickness in muscle capillaries of normal and spontaneously diabetic Macaca nigra.
abstract: The thickness of the capillary basement membrane of femoral muscle was examined in normal and spontaneously diabetic Macaca nigra. Thickness correlated significangly with the degree and severity of diabetes; greater thickness was associated with decreased glucose tolerance, decreased serum insulin, and increased glucose and triglyceride. In normal monkeys, the average basement membrane thickness was 696 A and in diabetic monkeys, 837 A, The minimum basement membrane thickness was 524 A in normal monkeys and 634 A in diabetics. Normals differed significantly from diabetic monkeys.
mesh_terms: D000818:Animals; D000941:Antigens; D001485:Basement Membrane / Q000473:pathology; D001706:Biopsy; D001786:Blood Glucose / Q000378:metabolism; D002196:Capillaries / Q000473:pathology*; D003920:Diabetes Mellitus / Q000473:pathology*; D005260:Female; D005951:Glucose Tolerance Test; D006614:Hindlimb; D007328:Insulin / Q000097:blood; D008251:Macaca; D008297:Male; D009132:Muscles / Q000098:blood supply*; D014280:Triglycerides / Q000097:blood
chemical_list: D000941:Antigens; D001786:Blood Glucose; D007328:Insulin; D014280:Triglycerides