title: The immediate circulatory response to high-velocity missiles.
abstract: The immediate hemodynamic response to a high-velocity missile wound was studied in the hind legs of dogs. A spherical missile of constant mass and velocity was used. The immediate effect after the shot was a marked transient peak flow, which may be due to the effects of the pressure wave on the vascular bed, with a release of constrictor tone. The subsequent more constant increase of blood flow in the traumatized leg is of the same character as that seen following extensive soft-tissue contusion trauma. In addition to these local changes there was also a generalized effect with decreased blood pressure without a compensating increase in hear rate. This may be explained by the specific character of the trauma that a high-velocity missile produces.
mesh_terms: D000818:Animals; D001794:Blood Pressure; D002245:Carbon Dioxide / Q000097:blood; D004285:Dogs; D005260:Female; D006339:Heart Rate; D006439:Hemodynamics; D006614:Hindlimb / Q000293:injuries; D008297:Male; D010100:Oxygen / Q000097:blood; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood; D014948:Wounds, Gunshot / Q000503:physiopathology*
chemical_list: D002245:Carbon Dioxide; D012964:Sodium; D011188:Potassium; D010100:Oxygen