Accommodative effects of aceclidine in the treatment of glaucoma.
In 18 patients, 2% pilocarpine, 2% pilocarpine plus tropicamide 10:1, and 2% aceclidine were tested with respect to the degree of spasm of accommodation induced by these drugs. Aceclidine had the least effect on accommodation, making it the recommended drug for use in patients with glaucoma and considerable remaining accommodation, i.e., most patients under the age of 50 years.
D000065:Accommodation, Ocular / Q000187:drug effects*; D000328:Adult; D000367:Age Factors; D000577:Amides / Q000009:adverse effects / Q000627:therapeutic use; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008875:Middle Aged; D009216:Myopia / Q000139:chemically induced; D009883:Ophthalmic Solutions; D010862:Pilocarpine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D011725:Pyridines / Q000009:adverse effects / Q000627:therapeutic use; D011812:Quinuclidines / Q000009:adverse effects / Q000627:therapeutic use*
D000577:Amides; D009883:Ophthalmic Solutions; D011725:Pyridines; D011812:Quinuclidines; D010862:Pilocarpine