Aromatization of androstenedione by isolated human hairs.
The formation of (3-H) estrone has been demonstrated in human anagen scalp hair roots incubated with (1, 2, 6, 7-3H) androstenedione, and approximate rates of formation of 0.2 pmol of estrone/mg DNA/h were observed. Thus, hair is a potential site for the extraglandular formation of estrogen in man.
D000328:Adult; D000735:Androstenedione / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D004247:DNA / Q000032:analysis; D004970:Estrone / Q000378:metabolism*; D006197:Hair / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D013997:Time Factors
D004970:Estrone; D000735:Androstenedione; D004247:DNA