[HGH release after I.M. glucagon injection].
Intramuscular injection of glucagon was used to assess HGH release in 31 normal children and 4 hypopituitary dwarfs. The peak response in controls was obtained at 120 min. with values (nanograms) of 12.93 plus or minus 5.18 (p smaller than 0.0005). Values at 60 and 180 min. were equally significant when compared with basal (7.04 plus or minus 9.24, p smaller than 0.025 and 6.74 plus or minus 6.65, p smaller than 0.001). Hypopituitary dwarfs did not respond to glucagon injection.
D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D004393:Dwarfism, Pituitary / Q000175:diagnosis*; D005260:Female; D005934:Glucagon / Q000008:administration & dosage; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular; D008297:Male; D010902:Pituitary Gland / Q000187:drug effects; D013268:Stimulation, Chemical
D013006:Growth Hormone; D005934:Glucagon
Respuesta de la hormona del crecimiento (HGH) al glucagón intramuscular