Characterization of elevated fibrin split products following thermal injury.
These studies establish that the staphylococcal clumping test is superior to the tanned red cell hemagglutination inhibition immunoassay for monitoring fibrin split product concentration in burn sera. It is strongly suggested that the principal circulating degradation product is a complex of soluble fibrin monomer with fragment D. Finally, there does not appear to be any effect on measured fibrin split product concentration in sera of burn patients receiving prophylactic heparin or aspirin.
D001241:Aspirin / Q000627:therapeutic use; D002056:Burns / Q000097:blood*; D004211:Disseminated Intravascular Coagulation / Q000209:etiology* / Q000517:prevention & control; D004341:Drug Evaluation; D005337:Fibrin / Q000032:analysis*; D005340:Fibrinogen; D006385:Hemagglutination Inhibition Tests; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007118:Immunoassay / Q000379:methods; D011446:Prospective Studies; D013210:Staphylococcus / Q000187:drug effects*
D005337:Fibrin; D005340:Fibrinogen; D006493:Heparin; D001241:Aspirin