title: The place of surgery in nodular thyroid disease.
abstract: The case records of 419 patients undergoing thyroidectomy for nodular goitre are examined in the light of the final pathology and the incidence of carcinoma. In patients presenting with a clinically single nodule, the incidence of carcinoma was 10%; in multinodular goitres this incidence was 4%. A policy for the surgical treatment of nodular goitre is proposed.
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology / Q000601:surgery; D000236:Adenoma / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002277:Carcinoma / Q000453:epidemiology; D002291:Carcinoma, Papillary / Q000453:epidemiology / Q000601:surgery; D002648:Child; D005006:Ethnicity; D005260:Female; D006044:Goiter, Nodular / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012737:Sex Factors; D013019:South Africa; D013964:Thyroid Neoplasms / Q000453:epidemiology / Q000601:surgery; D013965:Thyroidectomy