Recent thoughts on the development of colorectal cancer.
Considerable evidence demonstrates that a relationship may exist between adenomatous polyps and carcinoma. While the evidence may be circumstantial, it is not unimpressive. A recently completed 18 year follow-up of patients with benign polyps initially fulgurated demonstrates a statistically significant higher incidence of the development in colorectal carcinoma in these patients than in the unaffected population.
D001808:Blood Vessels; D003110:Colonic Neoplasms / Q000209:etiology* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D007417:Intestinal Polyps / Q000150:complications* / Q000473:pathology; D008207:Lymphatic Metastasis; D008722:Methods; D009362:Neoplasm Metastasis; D011230:Precancerous Conditions / Q000209:etiology* / Q000473:pathology; D011379:Prognosis; D012004:Rectal Neoplasms / Q000209:etiology* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D013997:Time Factors