Ocular changes in epidermolysis bullosa letalis.
Ocular changes in a rare case of epidermolysis bullosa letalis included edema of the trabecular meshwork, ciliary body, lens, optic nerve, and formation of edema cysts in the iris. The retinal was completely detached and focally necrotic. Foci of necrosis and detachment of the retinal pigment epithelium were also observed with occasional breach in the Bruch's membrane. The choroid showed focal edema and congestion.
D001344:Autopsy; D002829:Choroid / Q000473:pathology; D002924:Ciliary Body / Q000473:pathology; D004487:Edema / Q000150:complications / Q000209:etiology; D004820:Epidermolysis Bullosa / Q000150:complications* / Q000235:genetics / Q000473:pathology; D005123:Eye / Q000473:pathology*; D005128:Eye Diseases / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000473:pathology*; D007498:Iris / Q000473:pathology; D007908:Lens, Crystalline / Q000473:pathology; D010375:Pedigree; D012162:Retinal Degeneration / Q000150:complications / Q000209:etiology / Q000473:pathology; D012163:Retinal Detachment / Q000150:complications / Q000209:etiology / Q000473:pathology; D014822:Vitreous Body / Q000473:pathology