The use of 51Cr for sheep red blood cell survival studies.
The red blood cell half-life as determined by 51Cr-labelled autologous cells in five adult sheep was 13.7 days.  In contrast, the red blood cell life span measured by cohort 59Fe-labelling in six adult sheep was 111.7 days.  The rapid loss of 51Cr-activity from the circulation appears to result from rapid elution of the label from the circulating red cells.  51Cr does not appear to be a suitable isotope for erythrokinetic studies in sheep.
D000818:Animals; D002470:Cell Survival; D002860:Chromium Radioisotopes; D004912:Erythrocytes / Q000502:physiology*; D005260:Female; D006207:Half-Life; D006454:Hemoglobins; D007504:Iron Radioisotopes; D007700:Kinetics; D012756:Sheep
D002860:Chromium Radioisotopes; D006454:Hemoglobins; D007504:Iron Radioisotopes