title: Pulsus paradoxus in asthmatic children.
abstract: Pulsus paradoxus is a useful physical sign in the assessment of the severity of asthma in adults. Whether this is also true for asthmatic children was determined by measuring respiratory fluctuations in systolic blood pressure during attacks of asthma in 24 children. A decrease in systolic pressure during inspiration exceeding 15 mm Hg was found only when the 1-second forced expiratory volume was less tha 60 percent of the predicted value. There was a highly significant (P smaller than 0.001) correlation between the degree of pulsus paradoxus and the severity of airway obstruction. In nonasthmatic children the systolic pressure was found to fluctuate by as much as 7 mm Hg during the respiratory cycle. It is concluded that, as in adults, the presence of pulsus paradoxus (larger than or equal to 15 mm Hg) in children indicates that their asthma is very severe.
mesh_terms: D000293:Adolescent; D000328:Adult; D000402:Airway Obstruction / Q000175:diagnosis; D001249:Asthma / Q000175:diagnosis* / Q000188:drug therapy; D001794:Blood Pressure; D002648:Child; D002675:Child, Preschool; D006801:Humans; D009921:Metaproterenol / Q000627:therapeutic use; D011674:Pulse; D012129:Respiratory Function Tests
chemical_list: D009921:Metaproterenol