[Conservative treatment of lung cancer].
393 inoperable patients with lung cancer of stage III and IV were given two or three chemical substances according to the schemes applied or one of cytostatics with telegamma therapy. Control patients were administered only cyclophosphan or subjected to telegamma therapy. The best immediate and late results were noted in objects receiving either three substances or gamma-radiation with antimetabolites, 5-fluoruracil in particular, An efficacy of the treatment was estimated depending on the morphological structure of a tumor. A toxic effect of the therapy employed on the gastrointestinal tract, hemopoiesis was studied.
D000230:Adenocarcinoma / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000628:therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy*; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D011867:Radioisotope Teletherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage; D014455:Ukraine; D014747:Vinblastine / Q000627:therapeutic use
D014747:Vinblastine; D003520:Cyclophosphamide; D005472:Fluorouracil; D008727:Methotrexate
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