Gonadoblastoma associated with embryonal carcinoma in an anatomically normal man.
A case of gonadoblastoma associated with embryonal carcinoma in a normally decended testis of an anatomically normal 20-year-old man is reported. The patient had enlargment of the supraclavicular lymph nodes, which contained metastatic yolk sac tumor. Pulmonary and abdominal metatases were present. Despite chemotherapy and radiotherapy the patient died 9 months after presentation. Review of the literature concerning gonadoblastoma in phenotypic male patients is presented.
D000008:Abdominal Neoplasms; D000328:Adult; D004407:Dysgerminoma / Q000150:complications* / Q000473:pathology; D006801:Humans; D007985:Leydig Cells; D008175:Lung Neoplasms; D008207:Lymphatic Metastasis; D008297:Male; D009362:Neoplasm Metastasis; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D010641:Phenotype; D012708:Sertoli Cells; D013724:Teratoma / Q000150:complications* / Q000473:pathology; D013736:Testicular Neoplasms / Q000473:pathology