[Origin of Luciani periods during the effects of acetylcholine and eserine on the automation of Purkinje fibers].
Experiments were conducted on the isolated rabbit hearts with a complete atrio-ventricular block. It was shown that under the effect of acetylcholine (1.10(-7)-2.10(-6)g/ml) or eserine (1.10(-7)-2.10(-6)g/ml) there can occur Luciani periods which disappeared under the action of atropine (1.10(-6)g/ml). With the aid of microelectrodes it was revealed that Luciani periods appearing under the effect of acetylcholine or eserine were caused by periodic depression of automation of the Purkinje's fibers. This automation depression is regarded to be the result of a relative insufficiency of the active ionic transport processes.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000139:chemically induced*; D004285:Dogs; D004594:Electrophysiology; D006323:Heart Arrest / Q000139:chemically induced*; D006329:Heart Conduction System / Q000187:drug effects*; D010830:Physostigmine / Q000494:pharmacology*; D011690:Purkinje Fibers / Q000187:drug effects* / Q000502:physiology; D011817:Rabbits; D051381:Rats
D010830:Physostigmine; D000109:Acetylcholine
Vozniknovenie periodov Liuchiani pri deĭstvii atsetilkholina i ézerina na avtomatiiu volokon Purkin'e