title: Tissue reactions to some dental implant materials. An in vivo study in white rats.
abstract: In a 10 week experimental investigation the tissue reactions to implantation of standardised test pieces made of a polysilicone, Silastic, Tantalum, Titanium and a cobalt-chromium alloy, Vitallium, were studied in the white rat. After 2 weeks, polysilicone, Tantalum and Titanium caused slight reactions whilst a comparatively strong round cell infiltration was observed around the cobalt-chromium test pieces. After 10 weeks, no cellular infiltration was demonstrable around any of the implant materials. The now all appeared inert and were surrounded by a tough connective tissue.
mesh_terms: D000818:Animals; D002857:Chromium / Q000009:adverse effects; D003035:Cobalt / Q000009:adverse effects; D003722:Dental Alloys; D003757:Dental Implantation; D003764:Dental Materials / Q000009:adverse effects; D005549:Foreign-Body Reaction; D051381:Rats; D012828:Silicones / Q000009:adverse effects; D013635:Tantalum / Q000009:adverse effects; D014025:Titanium / Q000009:adverse effects
chemical_list: D003722:Dental Alloys; D003764:Dental Materials; D012828:Silicones; D002857:Chromium; D003035:Cobalt; D013635:Tantalum; D014025:Titanium