title: Distribution of latex-ingesting cells, T cells, and B cells in the peripheral blood of patients with malignant melanoma.
abstract: The distribution among peripheral blood mononuclear cells of latex-ingesting cells, T cells, and B cells was determined with samples from 38 normal donors and 25 patients with malignant melanoma. The mean percentage of latex-ingesting cells, as well as B and T cells, was significantly reduced in the 25 patients with malignant melanoma, stages I and II, compared to the controls. Several explanations for these unexpected findings were considered; possibly the presence of occult neoplasm was responsible for the observed changes in cell distribution.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001402:B-Lymphocytes; D002469:Cell Separation; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007104:Immune Adherence Reaction; D007840:Latex; D007958:Leukocyte Count; D008297:Male; D008545:Melanoma / Q000097:blood*; D008863:Microspheres; D008875:Middle Aged; D009000:Monocytes; D010587:Phagocytosis; D013601:T-Lymphocytes
chemical_list: D007840:Latex