The presence of Hb J alpha15 Gly leads to Asp in an Italian family in the United States.
A fast-moving hemoglobin variant was detected by electrophoresis. Sequence analysis revealed a substitution of glycine by aspartic acid at position 15 in the alpha chain.
D001224:Aspartic Acid; D001322:Autoanalysis; D001797:Blood Protein Electrophoresis; D002848:Chromatography, DEAE-Cellulose; D002849:Chromatography, Gas; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D002855:Chromatography, Thin Layer; D003911:Dextrans; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis; D005998:Glycine; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans; D007558:Italy / Q000208:ethnology; D008297:Male; D014481:United States
D003911:Dextrans; D006455:Hemoglobins, Abnormal; D001224:Aspartic Acid; D005954:Glucosephosphate Dehydrogenase; D005998:Glycine