The interaction of the protein and phospholipid components of tissue thromboplastin (factor III) with the factors VII and X.
The protein and phospholipid components of tissue thromboplastin have been isolated and their interactions with factor VII and factor Xa have been studied by gel filtration, centrifugation and heat inactivation. As expected, the phospholipid fraction bound both factors in the presence of Ca2+. No evidence for an interaction of apoprotein III with factor VII or Xa was obtained.
D001059:Apoproteins / Q000378:metabolism*; D002118:Calcium; D002498:Centrifugation; D002850:Chromatography, Gel; D005167:Factor VII / Q000378:metabolism*; D005170:Factor X / Q000378:metabolism*; D006358:Hot Temperature; D010743:Phospholipids / Q000378:metabolism*; D013925:Thromboplastin / Q000378:metabolism*
D001059:Apoproteins; D010743:Phospholipids; D005167:Factor VII; D005170:Factor X; D013925:Thromboplastin; D002118:Calcium