[The effect of methyluracil on protein and amino acid concentration in HEp-2 cells].
Methyluracil doses from 1 to 50 mg/ml induced an increase of total nucleinic acids in the nuclei and the protein in the cytoplasm of the HEp-2 cells. 20 mg/ml of methyluracil gave a progressive increase in the nucleinic acid concentration in the cells--from 122 to 197 %. A relatively stable increase of protein at all the time intervals was induced by a dose of 30 mg/ml (132--145%). This is in favour of an increase in cell metabolic processes under the influence of methyluracil.
D002294:Carcinoma, Squamous Cell; D002460:Cell Line; D007822:Laryngeal Neoplasms; D009363:Neoplasm Proteins / Q000096:biosynthesis*; D009696:Nucleic Acids / Q000096:biosynthesis*; D013268:Stimulation, Chemical; D014498:Uracil / Q000031:analogs & derivatives* / Q000494:pharmacology
D009363:Neoplasm Proteins; D009696:Nucleic Acids; D014498:Uracil
Vliianie metiluratsila na soderzhanie belka i nukleinovykh kislot v kletkakh HEp-2