title: [Blast transformation of the peripheral lymphocytes in cervical cancer during the radiotherapy process].
abstract: The reaction of blast-transformation of peripheral blood lymphocytes was studied in 60 patients with cervical cancer depending on a stage and radiotherapy applied. A progression of the tumor process reduces the capacity of peripheral blood lymphocytes for blasttransformation in the FHA stimulated culture. The conducted radiotherapy would enhance a suppression of functional properties of T-lymphocytes. The use of the blasttransformation reaction seems to be possible for estimation of changes in the cellular immunity in oncological patients during radiotherapy.
mesh_terms: D002278:Carcinoma in Situ / Q000276:immunology / Q000532:radiotherapy; D002478:Cells, Cultured; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000528:radiation effects; D037102:Lectins / Q000494:pharmacology; D008213:Lymphocyte Activation / Q000187:drug effects / Q000528:radiation effects*; D011830:Radiation Effects; D011879:Radiotherapy Dosage; D002583:Uterine Cervical Neoplasms / Q000276:immunology* / Q000532:radiotherapy
chemical_list: D037102:Lectins
vernacular_title: Blastnaia transformatsiia limfotsitov perifericheslkĭ krovi u bol'nykh rakom sheĭki v protsesse luchevogo lecheniia