Serum FSH and synthetic LHRG response in pregnant women at term and in the newborn.
Serum immunoreactive FSH was undetectable in a) pregnant women past 38 weeks of gestation, b) newborn infants, and c) anencephalic infants. The intravenous administration of 100 mug of synthetic LHRH elicited no FSH release in each instance. These results seem to indicate that the absence of FSH in serum in pregnant women in the last trimester, as well as in the newborn, is due to the suppressive effect on the anterior pituitary of the increased amount of circulating sex steroids.
D000757:Anencephaly / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D005313:Fetal Death / Q000097:blood; D005640:Follicle Stimulating Hormone / Q000032:analysis / Q000097:blood* / Q000378:metabolism; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D006801:Humans; D007231:Infant, Newborn; D007743:Labor, Obstetric; D008297:Male; D010903:Pituitary Gland, Anterior / Q000187:drug effects; D011247:Pregnancy; D011263:Pregnancy Trimester, Third
D007987:Gonadotropin-Releasing Hormone; D005640:Follicle Stimulating Hormone