[Effect of light deprivation and light stimulation on the RNA content of neurons in the adult rat visual analyzer].
By means of two-wavelength visual cytospectrophotometry, a content of nucleic acids per cell was determined in the gallocyanin chrome alum stained sections of the adult rat nervous system. Illumination of normal rats with constant or flashing light for 2 hr resulted in an accumulation of RNA in II--III layer neurons of the visual cortex and in the retina ganglionic neurons. After the rats had been kept for 30 days in a complete darkness the nucleic acid content in their visual cortex neurons was increased. Illumination of these animals with constant or flashing light for 2 hr gave rise to a return of the nucleic acid content in the cortex neurons to the normal. Under the effect of 30-day light deprivation, the nucleic acid content in the retina ganglionic neurons remained unchanged. Illumination of the light-deprived rats with flashing light for 2 hr also did not change RNA content in these retina neurons. The data obtained indicate the prolonged hypofunction in adult animals to induce marked changes in nucleic acid metabolism in the neurons of visual analyser. A relationship between the function and metabolism in adult neurons is emphasized; differences of the function-dependent metabolic responses in the cell structures of central and peripheral parts of the visual analyser are discussed.
D000818:Animals; D008297:Male; D009430:Neural Analyzers / Q000378:metabolism / Q000502:physiology*; D009474:Neurons / Q000378:metabolism; D010775:Photic Stimulation; D012313:RNA / Q000378:metabolism*; D051381:Rats; D012160:Retina / Q000378:metabolism / Q000502:physiology*; D012683:Sensory Deprivation; D014785:Vision, Ocular; D014793:Visual Cortex / Q000378:metabolism / Q000502:physiology*
D012313:RNA
Vliianie svetovoĭ deprivatsii i stimuliatsii svetom na soderzhanie RNK v neĭronakh zritel'nogo analizatora vzroslykh krys