The fate of UV-induced pyrimidine dimers in the nuclear and mitochondrial DNAs of Saccharomyces cerevisiae on various postirradiation treatments and its influence on survival and cytoplasmic "petite" induction.
The photoreactivability of UV-induced pyrimidine dimers in the nuclear and mitochondrial DNAs of Saccharomyces cerevisiae has been investigated in conjunction with the fate of these photoproducts following postirradiation dark incubation in saline and nutrient media. In all instances, survival and "petite" induction were measured. An attempt has been made to relate these results to present ideas on the repair of UV damages in DNA.
D002467:Cell Nucleus / Q000378:metabolism / Q000528:radiation effects; D002470:Cell Survival / Q000528:radiation effects; D003593:Cytoplasm / Q000378:metabolism / Q000528:radiation effects; D004247:DNA / Q000378:metabolism / Q000528:radiation effects*; D004272:DNA, Mitochondrial / Q000378:metabolism / Q000528:radiation effects; D008027:Light; D009154:Mutation; D011742:Pyrimidine Nucleotides / Q000528:radiation effects*; D011830:Radiation Effects; D012441:Saccharomyces cerevisiae / Q000378:metabolism / Q000528:radiation effects*; D014466:Ultraviolet Rays
D004272:DNA, Mitochondrial; D011742:Pyrimidine Nucleotides; D004247:DNA