[T- and B-lymphocytes in patients with kidney transplants].
T and B cells were estimated in kidney allograft recipients under immunosuppressive therapy by spontaneous rosette formation with sheep erythrocytes and fluorescent staining with anti-immunoglobulin serum. Pronounced lymphopenia could be shown in all patients when compared with normal as well as uremic controls. Under standard immunosuppression with azathioprine and oral steroids T cells were reduced to 840 +/- 215 and B cells to 286 +/- 69 per mm3 blood. Lymphopenia was further augmented by additional intravenous treatment with prednisolone in high dosage (1g). Under these conditions a prevailing reduction of T cells was found.
D001402:B-Lymphocytes; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology; D016030:Kidney Transplantation; D008231:Lymphopenia / Q000097:blood / Q000139:chemically induced; D013601:T-Lymphocytes; D014181:Transplantation Immunology; D014184:Transplantation, Homologous
D007166:Immunosuppressive Agents
T- und B-Lymphozyten bei nierentransplantierten Patienten