[Integration of palmitat-1-14-C in lecithine and phospholipid content in normal and micro-embolized rabbit lungs (author's transl)].
Glass microspheres were used for a diffuse pulmonary microembolisation, as a modell for shock lung. Microembolisation is regarded as an important factor in pathogenesis of shock lung. The capacity of lung for lecithin synthesis was measured with palmitat-1-14-C incorporation. The phospholipid content and the composition of the fatty acids of lecithin were investigated. From the results it was possible, that the surfactant system may alterated by the vascular blocking. The dates supporting the importance of microembolisation in pathogenesis of shock lung.
D000818:Animals; D002250:Carbon Radioisotopes; D004247:DNA / Q000378:metabolism; D004195:Disease Models, Animal; D005227:Fatty Acids / Q000378:metabolism; D005260:Female; D005898:Glass; D008168:Lung / Q000378:metabolism*; D008297:Male; D008863:Microspheres; D010169:Palmitic Acids / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000096:biosynthesis* / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D011655:Pulmonary Embolism / Q000150:complications / Q000378:metabolism*; D011817:Rabbits; D012769:Shock; D013499:Surface Properties
D002250:Carbon Radioisotopes; D005227:Fatty Acids; D010169:Palmitic Acids; D010713:Phosphatidylcholines; D010743:Phospholipids; D004247:DNA
Einbau von Palmitat-1-14-C in Lecithin und Phospholipidgehalt in normalen und mikroembolisierten Kaninchenlungen. Modellstudie zur sogenannten Schocklunge