title: Different sensitivities of avian- and mammalian-haemoglobin synthesis to elevated temperatures.
abstract: Avian- and mammalian-haemoglobin synthesis show different sensitivities to elevated temperatures. Temperature-dependent, reversible polyribosome disaggregation in avian cells occurs only at 45 degrees C, which is 3 degrees higher than the temperature for mammalian cells, and seems to be due to a block in the initiation of new polypeptide chains. The implications of these findings are discussed.
mesh_terms: D000818:Animals; D002458:Cell Fractionation; D002499:Centrifugation, Density Gradient; D004372:Ducks; D004912:Erythrocytes / Q000378:metabolism*; D006454:Hemoglobins / Q000096:biosynthesis*; D007930:Leucine / Q000378:metabolism; D011132:Polyribosomes / Q000378:metabolism* / Q000648:ultrastructure; D014176:Protein Biosynthesis; D011817:Rabbits; D013045:Species Specificity; D013696:Temperature
chemical_list: D006454:Hemoglobins; D007930:Leucine