Growth kinetics of solid tumors. Implications for chemotherapy.
More precise definition of the cytokinetic parameters of human tumor growth will clearly help both in predicting the outcome of disease in individual patients and in planning the dosage schedules of single chemotherapeutic agents and combinations of agents to achieve optimal results.
D000208:Acute Disease; D000230:Adenocarcinoma / Q000378:metabolism; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002455:Cell Division / Q000187:drug effects; D003110:Colonic Neoplasms / Q000378:metabolism; D046508:Culture Techniques; D003561:Cytarabine / Q000494:pharmacology; D004247:DNA / Q000096:biosynthesis; D006801:Humans; D007700:Kinetics; D007938:Leukemia / Q000473:pathology; D008540:Meiosis / Q000187:drug effects; D008545:Melanoma / Q000473:pathology; D008938:Mitosis / Q000187:drug effects; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology; D009374:Neoplasms, Experimental / Q000378:metabolism / Q000473:pathology; D051381:Rats; D013936:Thymidine / Q000378:metabolism / Q000494:pharmacology; D014316:Tritium; D014747:Vinblastine / Q000494:pharmacology
D000970:Antineoplastic Agents; D003561:Cytarabine; D014316:Tritium; D014747:Vinblastine; D004247:DNA; D013936:Thymidine