title: [Age differences in the reactivity of the organism after administration of isoprenaline in rats (author's transl)].
abstract: To three age groups of animals 2, 6 and 12 months old isoprenaline was administered in amounts of 8 mg/kg body weight. In these rats changes in the weight of some organs after administration of isoprenaline were followed-up. In the oldest group of rats were the myocardial lesions were most severe, the authors found the slightest oedematous response of the myocardium. The oedema of their aorta, on the other hand, was most marked. The weight of the adrenals, contrary to younger groups, did not change in the course of the experiment.
mesh_terms: D000222:Adaptation, Physiological / Q000187:drug effects*; D000367:Age Factors; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D007545:Isoproterenol / Q000494:pharmacology*; D008297:Male; D009929:Organ Size; D051381:Rats
chemical_list: D007545:Isoproterenol
vernacular_title: Vĕkové razdíly v reaktibilitĕ organismu po aplikaci izoprenalinu u krys