title: Diazoxide for hypertensive crisis.
abstract: Diazoxide is a potent and safe antipressor agent for parenteral administration in hypertensive emergencies. Its rapidity of effect provides distinct advantages. Drug resistance does not develop in responsive patients and adverse effects are mild and infrequent. The minor changes in blood urea concentration, despite a marked reduction in blood pressure, enhance the usefulness of diazoxide in azotemic hypertensive patients.
mesh_terms: D000293:Adolescent; D002302:Cardiac Output / Q000187:drug effects; D003981:Diazoxide / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D005919:Glomerular Filtration Rate; D006207:Half-Life; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D006974:Hypertension, Malignant / Q000188:drug therapy; D007022:Hypotension / Q000139:chemically induced; D007275:Injections, Intravenous; D008297:Male; D009325:Nausea / Q000139:chemically induced; D014655:Vascular Resistance / Q000187:drug effects; D014839:Vomiting / Q000139:chemically induced
chemical_list: D003981:Diazoxide