[Morphological aspects of the functional stability of the kidney].
Specific features of the internal architectonics of the secondary kidney have been analyzed from standpoints of main propositions of cybernetics. The high stability of the organ as a biological system is determined by a great number of non-equivalent elements both in the composition of the nephron in the level of coalition of nephrons and in other subsystems. It promotes 1) preservation of a part of neurons under extreme effects, 2) duplication, 3) creation of optimal variants of active functioning coalitions of nephrons, 4) maintenance of optimal regimen of work of the nephron and kidney as a whole. Specialization of cells, their ability to regenerate, control in many levels also contribute to stability. It is supposed that non-equivalence of the elements of subsystems in ontogenesis is sustained by their asynchronous development, while in phylogenesis--by intratissue divergence.
D000818:Animals; D002454:Cell Differentiation; D006801:Humans; D007668:Kidney / Q000033:anatomy & histology / Q000502:physiology*; D009399:Nephrons / Q000033:anatomy & histology / Q000502:physiology; D012038:Regeneration
Morfologicheskie aspekty funktsional'noĭ ustoĭchivosti pochki