Possible antineoplastic agents I.
A few thalidomide and glutarimide derivatives were synthesized. Several compounds possessed significant antineoplastic activity against Ehrlich ascites carcinoma in Swiss albino mice.
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000627:therapeutic use; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy; D051379:Mice; D009574:Nitro Compounds; D010797:Phthalimides / Q000138:chemical synthesis / Q000627:therapeutic use; D011728:Pyridones / Q000138:chemical synthesis* / Q000627:therapeutic use; D013329:Structure-Activity Relationship; D013792:Thalidomide / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000627:therapeutic use
D000970:Antineoplastic Agents; D009574:Nitro Compounds; D010797:Phthalimides; D011728:Pyridones; D013792:Thalidomide