Identification of phosphorodiamidic acid mustard as a human metabolite of cyclop  hosphamide.
An active metabolite of cyclophosphamide, N,N-bis(2-chloroethyl)phosphorodiamidic acid, has been confirmed as a circulating and excreted metabolite in patients receiving the drug in therapy, by selected ion monitoring on a gas chromatograph mass spectrometer.
D002849:Chromatography, Gas; D003520:Cyclophosphamide / Q000031:analogs & derivatives / Q000378:metabolism* / Q000627:therapeutic use; D006801:Humans; D013058:Mass Spectrometry; D009369:Neoplasms / Q000188:drug therapy
D003520:Cyclophosphamide