Fracture callus cartilage differentiation in vitro.
An in vitro model has been devised to study the differentiation and calcification of fibrocartilage from fracture calluses. Morphological and biochemical studies substantiating cartilage metaplasia in vitro are presented. A role that such a model may play in the study of cartilage calcification is suggested.
D000469:Alkaline Phosphatase; D000818:Animals; D002146:Bony Callus / Q000201:enzymology / Q000378:metabolism / Q000473:pathology*; D002113:Calcification, Physiologic; D002356:Cartilage / Q000201:enzymology / Q000378:metabolism / Q000473:pathology*; D002454:Cell Differentiation; D046508:Culture Techniques; D005360:Fibula / Q000293:injuries; D005596:Fractures, Closed; D008297:Male; D008954:Models, Biological; D011817:Rabbits; D013978:Tibial Fractures; D014945:Wound Healing
D000469:Alkaline Phosphatase