Nitrous oxide as an analgesic in acute myocardial infarction.
Nitrous oxide in a concentration of 35% has been shown to ameliorate the pain of acute myocardial infarction. This conclusion was reached on the basis of a double-blind study in 69 patients and a clinical study in an additional 42 patients. The use of nitrous oxide was not accompanied by hemodynamic changes or significant adverse reactions.
D000208:Acute Disease; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D004361:Drug Tolerance; D049691:History, Medieval; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy*; D009609:Nitrous Oxide / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D010101:Oxygen Consumption; D010146:Pain / Q000188:drug therapy*; D010919:Placebos; D011674:Pulse / Q000187:drug effects; D012138:Respiratory Therapy
D010919:Placebos; D009609:Nitrous Oxide