Thyroid allograft immunogenicity is reduced after a period in organ culture.
The survival time of mouse thyroid, transplanted under the kidney capsule of an H-2 incompatible recipient, is extended by holding the thyroid in organ culture for 12 days prior to transplantation.
D000818:Animals; D000917:Antibody Formation; D006084:Graft Rejection; D006649:Histocompatibility Antigens; D007457:Iodine Radioisotopes; D007668:Kidney / Q000601:surgery; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D009924:Organ Culture Techniques; D013961:Thyroid Gland / Q000276:immunology / Q000637:transplantation*; D014021:Tissue Preservation; D014022:Tissue Survival; D014184:Transplantation, Homologous
D006649:Histocompatibility Antigens; D007457:Iodine Radioisotopes