[Influence of ribose on 2,3-diphosphoglycerate concentrations in human erythrocytes].
The effect of ribose on the 2,3-diphosphoglycerate concentration (2,3-DPG) of human red blood cells was investigated and compared to the effect of inosine. Ribose as well as inosine increases 2,3-DPG. Most impressing effects can be demonstrated on stored blood, which is poor in 2,3-DPG concentration. Physiologic 2,3-DPG-concentrations, however, may be increased too. Generally the effect of inosine is greater than the effect of ribose. When ribose is applicated intravenously a slight increase in 2,3-DPG is found. Both compounds own characteristic side-effects, which diminish their value for therapeutical purposes.
D004163:Diphosphoglyceric Acids / Q000097:blood*; D004912:Erythrocytes / Q000032:analysis / Q000187:drug effects*; D006801:Humans; D007275:Injections, Intravenous; D007288:Inosine / Q000009:adverse effects / Q000494:pharmacology; D012266:Ribose / Q000009:adverse effects / Q000494:pharmacology*
D004163:Diphosphoglyceric Acids; D007288:Inosine; D012266:Ribose
Der Einfluss von Ribose auf die 2, 3-Diphosphoglycerat-Konzentration menschlicher erythrozyten