title: Cysteine biosynthesis in Aspergillus nidulans.
abstract: The existence of two postulated pathways of anabolic cysteine biosynthesis in Aspergillus midulans was investigated. No activities of the postulated pathway involving S-sulfocysteine as intermediate have been detected. Investigations on cyteine and methionine requiring mutants revealed independent regulation of O-acetylserine sulfhydrylase by endogeneous cysteine and methionine pools. The reaction catalysed by O-acetylserine sulfhydrylase is postulated as the only anabolic pathway of cysteine biosynthesis in A. nidulans.
mesh_terms: D001233:Aspergillus nidulans / Q000201:enzymology / Q000378:metabolism*; D003545:Cysteine / Q000096:biosynthesis*; D008190:Lyases / Q000378:metabolism; D008715:Methionine / Q000378:metabolism; D009154:Mutation; D012694:Serine / Q000031:analogs & derivatives
chemical_list: D012694:Serine; D008715:Methionine; D008190:Lyases; D003545:Cysteine