[Use of scanning electron microscopy for studying the intersection of lymphocytes with tumor cells].
With the aid of steroscan microscopy it was found that the state of surface membranes of the cells under study showed a significant change during the interaction of lymphocytes of BALB/C mice--bearers of methylcholantrene-induced sarcoma--with autologous tumour cells. Lymphocytes separated from the autologous tumour cells by a millipore filter formed long cytoplasmic processes which passed through the filter pores and came into close contact with tumour cells. Tumour cells acquired a spherical shape, and became swollen; "openings" appeared in the surface membrane, and this led to cell lysis.
D000818:Animals; D002462:Cell Membrane / Q000276:immunology*; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000276:immunology*; D008748:Methylcholanthrene; D051379:Mice; D008807:Mice, Inbred BALB C; D008855:Microscopy, Electron, Scanning; D012513:Sarcoma, Experimental / Q000139:chemically induced / Q000276:immunology*
D008748:Methylcholanthrene
Primenenie èlektronnoĭ skaniruiushcheĭ mikroskopii dlia izucheniia vzeimodeĭstviia limfotsitov s opukholevymi kletkami.