title: [The effect of Tropaacidester Sch 1000 on respiratory resistance (author's transl)].
abstract: The effect of Tropaacidester Sch 1000 on respiratory resistance, intrathoracical volume, peripheral blood pressure, and heart frequency over a period of 24 hours were examined in ten patients suffering from obstructive respiratory diseases. Compared with placebo 2 puffs of Sch 1000 administered 6 times significantly decreased respiratory resistance. The bronchodilatatory effects of Sch 1000 and Orciprenalin seemed to be almost identical. Side effects after application of Sch 1000 have not been observed.
mesh_terms: D000336:Aerosols; D000403:Airway Resistance / Q000187:drug effects; D001249:Asthma / Q000188:drug therapy*; D001285:Atropine / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D002940:Circadian Rhythm; D004952:Esters; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos; D010993:Plethysmography, Whole Body; D011674:Pulse / Q000187:drug effects; D012119:Respiration / Q000187:drug effects; D014326:Tropanes / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000336:Aerosols; D001993:Bronchodilator Agents; D004952:Esters; D010919:Placebos; D014326:Tropanes; D001285:Atropine
vernacular_title: Therapie der obstruktiven Atemwegerkrankung mit einem Atropinderivat (Sch 1000)