[Effect of antibiotic therapy on the experimental production of antiviral antibodies].
Because of the practical value of the study of peculiar properties of antinfluenza immunity under conditions of the use of tetracycline, streptomycin and penicillin, the experiments were performed on albino mice and rats. The studies showed that the antibiotics inhibited the intensity of production of specific antibodies, i.e. antihemagglutinines and virus neutralizing antibodies in the process of antiinfluenza immunization of the animals which must be connected with changes in the cells of the immunoreactive system, suppression of the activity of the metabolic processes.
D000281:Administration, Intranasal; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000914:Antibodies, Viral / Q000032:analysis*; D000917:Antibody Formation / Q000187:drug effects*; D000956:Antigens, Viral / Q000008:administration & dosage; D002642:Chick Embryo; D003864:Depression, Chemical; D006385:Hemagglutination Inhibition Tests; D007109:Immunity / Q000187:drug effects; D007114:Immunization; D007273:Injections, Intramuscular; D051379:Mice; D009500:Neutralization Tests; D009976:Orthomyxoviridae Infections / Q000188:drug therapy / Q000276:immunology; D010406:Penicillins / Q000627:therapeutic use; D051381:Rats; D013307:Streptomycin / Q000627:therapeutic use; D013752:Tetracycline / Q000627:therapeutic use; D013997:Time Factors
D000900:Anti-Bacterial Agents; D000914:Antibodies, Viral; D000956:Antigens, Viral; D010406:Penicillins; D013752:Tetracycline; D013307:Streptomycin
Vliianie antibiotikoterapii na vyrabotku protivovirusnykh antitel v éksperimente