Effect of prostaglandin a1 on acute renal failure in the rat.
In an attempt to alter the natural course of glycerol and uranyl nitrate induced acute ranal failure in the rat, the vasodilator, prostaglandin A1 was adminstered systemically at varying times during the induction phase of renal failure.  According to the method used, no significant beneficial effect could be demonstrated in either experimental model.
D058186:Acute Kidney Injury / Q000139:chemically induced / Q000188:drug therapy*; D000818:Animals; D005260:Female; D005990:Glycerol; D009566:Nitrates; D011454:Prostaglandins A / Q000627:therapeutic use*; D051381:Rats; D014501:Uranium
D009566:Nitrates; D011454:Prostaglandins A; D014501:Uranium; D005990:Glycerol