title: Fracture callus cartilage differentiation in vitro.
abstract: An in vitro model has been devised to study the differentiation and calcification of fibrocartilage from fracture calluses. Morphological and biochemical studies substantiating cartilage metaplasia in vitro are presented. A role that such a model may play in the study of cartilage calcification is suggested.
mesh_terms: D000469:Alkaline Phosphatase; D000818:Animals; D002146:Bony Callus / Q000201:enzymology / Q000378:metabolism / Q000473:pathology*; D002113:Calcification, Physiologic; D002356:Cartilage / Q000201:enzymology / Q000378:metabolism / Q000473:pathology*; D002454:Cell Differentiation; D046508:Culture Techniques; D005360:Fibula / Q000293:injuries; D005596:Fractures, Closed; D008297:Male; D008954:Models, Biological; D011817:Rabbits; D013978:Tibial Fractures; D014945:Wound Healing
chemical_list: D000469:Alkaline Phosphatase