title: Morphological changes in maternal lymphocytes in pregnancy.
abstract: By use of staining with toluidine blue, the changes in the nucleoli of lymphocytes in 150 healthy women were studied. The patients were divided into five groups: non-pregnant women; women in the first, second and third trimesters of pregnancy; and women who were five days post partum. A progressive and statistically significant rise in the number of lymphocytes with micronucleoli was found during pregnancy and there was a fall after delivery. This increase was associated with a decrease in the incidence of ring-shaped nucleoli. There were no  significant changes in the absolute number of lymphocytes and in "active" lymphocytes during pregnancy.
mesh_terms: D001772:Blood Cell Count; D002466:Cell Nucleolus / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007962:Leukocytes; D008214:Lymphocytes / Q000648:ultrastructure*; D049590:Postpartum Period; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D013997:Time Factors; D014048:Tolonium Chloride
chemical_list: D014048:Tolonium Chloride