The prevalence of mycoplasmal complement-fixing antibodies in sarcoidosis.
Complement-fixing antibody titers to Mycoplasama pnuemoniae were measured in the sera of 31 patients with sarcoidosis and 31 control subjects matched by age, sex, and race. Data indicated a binomial distribution and a geometric mean titer of 1:32 in patients with sarcoidosis. In contrast, the control data were skewed,with a geometric mean titer of less than 1:8. Possible explanations include generalized increase in antibody formation, unusual susceptibility to infection with M.pneumoniae, and sarcoidosis as one consquence of infection with M.pneumoniae.
D000906:Antibodies / Q000032:analysis*; D000917:Antibody Formation; D000918:Antibody Specificity; D003168:Complement Fixation Tests; D006801:Humans; D009174:Mycoplasma / Q000276:immunology; D009175:Mycoplasma Infections / Q000276:immunology; D012507:Sarcoidosis / Q000276:immunology*
D000906:Antibodies