The HCG stimulation test in men with testicular disorders.
The rise in plasma testosterone levels following stimulation with human chorionic gonadotrophin (3000 i.u./day for 4 days) has been used as a test of interstitial cell function in normal men and men with testicular disorders. The large majority of patients with testicular disorders resulting in infertility, showed a subnormal testosterone response to stimulation. The most marked impairment was noted in those patients with the biopsy appearance of germinal cell arrest and Sertoli cell only syndrome.
D000328:Adult; D001706:Biopsy; D006063:Chorionic Gonadotropin; D002986:Clinical Trials as Topic; D006801:Humans; D008297:Male; D012708:Sertoli Cells / Q000473:pathology; D013733:Testicular Diseases / Q000473:pathology / Q000503:physiopathology*; D013737:Testis / Q000503:physiopathology; D013739:Testosterone / Q000097:blood*
D006063:Chorionic Gonadotropin; D013739:Testosterone