Objective evaluation of antitussive agents under clinical conditions.
A new method for objective assessment of cough under normal or pathological conditions is described. Thoracic coughing can be discriminated from any other pressure wave because of its relatively high frequency. This method was applied in a double blind crossover trial in 18 patients with respiratory disease.
D000996:Antitussive Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003061:Codeine / Q000627:therapeutic use; D003371:Cough / Q000188:drug therapy*; D004341:Drug Evaluation / Q000295:instrumentation; D006801:Humans
D000996:Antitussive Agents; D003061:Codeine