title: Spontaneous fluctuations of human placental lactogen during normal pregnancy.
abstract: Six women in the 3rd trimester of normal pregnancy had measurements of circulating placental lactogen (hPL) levels using a continuous blood sampling technique for 10-15 h. In addition, in 3 pregnant women hPL was assayed at 10-min intervals for 60-90 min. Both these procedures showed that hPL serum levels fluctuate irregularly during normal pregnancy. The magnitude and frequency of these fluctuations make the significance of a single hPL determination less reliable as a test of placental function.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D010920:Placenta / Q000502:physiology; D010928:Placental Lactogen / Q000097:blood*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D013997:Time Factors
chemical_list: D010928:Placental Lactogen