Effects of hormones and drugs on phosphoribosyl pyrophosphate concentrations in mouse liver.
Concentrations of phosphoribosyl pyrophosphate (PP-ribose-P) in mouse liver were studied as a function of time of day and following injection of a number of metabolites and drugs. A twofold diurnal variation in liver PP-ribose-P concentration was observed. Liver PP-ribose-P concentrations were elevated following injection of glucagon, insulin, epinephrine, and ethylaminothiasiazole.
D000818:Animals; D003837:Deoxy Sugars / Q000494:pharmacology*; D003847:Deoxyglucose / Q000494:pharmacology*; D004837:Epinephrine / Q000494:pharmacology; D005934:Glucagon / Q000494:pharmacology; D006728:Hormones / Q000494:pharmacology*; D007328:Insulin / Q000494:pharmacology; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D051379:Mice; D010428:Pentosephosphates / Q000378:metabolism*; D013830:Thiadiazoles / Q000494:pharmacology*; D013997:Time Factors; D014044:Tolbutamide / Q000494:pharmacology
D003837:Deoxy Sugars; D006728:Hormones; D007328:Insulin; D010428:Pentosephosphates; D013830:Thiadiazoles; D005934:Glucagon; D014044:Tolbutamide; D003847:Deoxyglucose; D004837:Epinephrine