Gas-liquid chromatographic determination of theophylline in human plasma.
A gas-liquid chromatographic method for the estimation of theophylline in human plasma is described. The method is based on the methylation of theophylline on-column and allows the determination of concentration of the drug down to the level of 1.0 mu-g/ml in plasma.
D002110:Caffeine / Q000032:analysis; D002849:Chromatography, Gas; D006358:Hot Temperature; D006801:Humans; D008722:Methods; D008745:Methylation; D008832:Microchemistry; D013806:Theophylline / Q000097:blood*
D002110:Caffeine; D013806:Theophylline