title: The use of the TDMAC-heparin shunt in replacement of the descending thoracic aorta.
abstract: The use of a flexible polyvinyl tube bonded with tridodecylmethylammonium-heparin (Gott) as a temporary shunt during the resection of lesions of the descending thoracic aorta has proven a safe and simple means of providing adequate circulation to the abdominal viscera and spinal cord. This technique avoids the metabolic consequences of ischemia to the lower body, diminishes left ventricular afterload during aortic clamping, and obviates the requirement for systemic anticoagulation associated with pump bypass. Between September 1970 and October 1974, 24 patients have been operated using the TDMAC shunt. There were two deaths (9%) among the 22 patients undergoing elective resections. Two patients with acutely dissecting and ruptured aneurysms expired. Followup data has been obtained on all patients from one to 46 months postoperative. The ease with which the shunt is inserted and its adaptability to varied clinical and anatomic situations is stressed. We feel that TDMAC-Heparin shunt provides the best method of circulatory support for elective operative procedures on the descending thoracic aorta.
mesh_terms: D000328:Adult; D000368:Aged; D001013:Aorta, Thoracic / Q000601:surgery*; D001014:Aortic Aneurysm / Q000601:surgery; D001243:Assisted Circulation / Q000295:instrumentation; D001807:Blood Vessel Prosthesis; D005260:Female; D005500:Follow-Up Studies; D006493:Heparin; D006801:Humans; D007440:Intubation; D008297:Male; D008875:Middle Aged; D011145:Polyvinyls; D000644:Quaternary Ammonium Compounds
chemical_list: D011145:Polyvinyls; D000644:Quaternary Ammonium Compounds; D006493:Heparin