Clonidine in the treatment of menopausal symptoms.
Twenty-five women suffering from climacteric complaints after surgical castration were treated with clonidine in a placebo controlled trial. Clonidine in the dose of 75 to 150 mug daily diminished the attack rates of flushing and sweating significantly. It can be recommended as a safe therapy for climacteric patients, at least those with contra-indications to oestrogen therapy.
D000328:Adult; D002979:Climacteric / Q000187:drug effects*; D002986:Clinical Trials as Topic; D003000:Clonidine / Q000494:pharmacology / Q000627:therapeutic use*; D003864:Depression, Chemical; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D010919:Placebos; D013546:Sweating / Q000187:drug effects*
D010919:Placebos; D003000:Clonidine