title: IgE in human eccrine sweat.
abstract: By the use of a sensitive and specific double antibody radioimmunoassay, immunoglobulin  E was demonstrated in sweat from 6 of 11 healthy volunteers; the concentrations of IgE ranged from 1 to 3.9 ng/ml of sweat.  Six of seven patients with dermatitis and elevated levels of serum IgE also had high IgE levels in sweat; the highest IgE value in sweat was 75.5 ng/ml and was noted in a patient with atopic dermatitis. Thus, all the main immunoglobulin classes can be demonstrated in eccrine sweat.
mesh_terms: D000328:Adult; D003872:Dermatitis / Q000276:immunology; D003876:Dermatitis, Atopic / Q000276:immunology; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male; D008875:Middle Aged; D011537:Pruritus / Q000276:immunology; D011565:Psoriasis / Q000276:immunology; D011863:Radioimmunoassay; D012871:Skin Diseases / Q000276:immunology*; D013542:Sweat / Q000032:analysis*
chemical_list: D007073:Immunoglobulin E