Total body irradiation in the management of malignant lymphoma.
A pilot study for the evaluation of fractionated total body irradiation in the management of disseminated lymphomas is reported. Nine patients were treated in the period February - August, 1973. A telecobalt unit with treatment distance of 328 cm was used. Daily fractions of 15 rad total body dose measured in the midpelvic plane were given for the first 5 days. Thereafter a dose of 10--15 rad per session was given every other day or at longer intervals depending on the leukocyte and thrombocyte count. The total dose for a full course varied between 200 and 265 rad in 5--12 weeks. The results of the study demonstrate the value of total body irradiation in the treatment of patients with stage III lymphosarcoma, and potentially in the management of disseminated mycosis fungoidis.
D000368:Aged; D003037:Cobalt Radioisotopes / Q000627:therapeutic use*; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000532:radiotherapy; D008223:Lymphoma / Q000532:radiotherapy*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000532:radiotherapy; D008228:Lymphoma, Non-Hodgkin / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000532:radiotherapy; D011867:Radioisotope Teletherapy; D011879:Radiotherapy Dosage
D003037:Cobalt Radioisotopes