title: Appraisal of the angiographic circulation time as an index of cerebral blood flow.
abstract: The relationship of the brain angiographic mode circulation time (AVCT) to the mean transit time of the vascular indicator C15O-labeled hemoglobin (tc15o) and the regional cerebral blood flow (rCBF) as measured by the clearance of the diffusible tracer H2-15O was examined in 38 patients with selected cerebral diseases. The results demonstrate a predictable relationship does exist between the rCBF and tc15o. This relationship is linear when plotted as tc15o vs. 1/CBF. Further, tc150 can be estimated with sufficient accuracy from the AVCT to permit at least a qualitative assessment of rCBF from the cerebral angiogram.
mesh_terms: D000792:Angiography; D001921:Brain / Q000098:blood supply*; D001927:Brain Diseases / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation; D006259:Craniocerebral Trauma / Q000000981:diagnostic imaging; D006454:Hemoglobins; D006801:Humans; D008433:Mathematics; D010103:Oxygen Isotopes; D011559:Pseudotumor Cerebri / Q000000981:diagnostic imaging; D011868:Radioisotopes; D012039:Regional Blood Flow; D013577:Syndrome; D013997:Time Factors
chemical_list: D006454:Hemoglobins; D010103:Oxygen Isotopes; D011868:Radioisotopes