Repair of double-strand breaks in Micrococcus radiodurans.
Micrococcus radiodurans has been shown to sustain double-strand breaks in its DNA after exposure to X-radiation. Following sublethal doses of X-rays (200 krad in oxygen or less), the cells were able to repair these breaks, and an intermediate fast-sedimenting DNA component seemed to be involved in the repair process.
D002462:Cell Membrane / Q000378:metabolism; D002701:Chloramphenicol / Q000494:pharmacology; D004260:DNA Repair / Q000187:drug effects; D004269:DNA, Bacterial / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D004926:Escherichia coli / Q000187:drug effects; D008837:Micrococcus / Q000378:metabolism* / Q000528:radiation effects; D008970:Molecular Weight; D011830:Radiation Effects; D012293:Rifampin / Q000494:pharmacology
D004269:DNA, Bacterial; D002701:Chloramphenicol; D012293:Rifampin