title: Factors that influence surgical wound infections. Role of prophylactic antibiotic therapy.
abstract: A comprehensive review of the factors responsible for postoperative wound sepsis is discussed, along with the experimental basis for the use of prophylatic antibiotics and a review of the results of the use of systemic and topical antibiotics on the incidence of surgical wound infections. Based on the data presented, suggestions are made which should minimize the development of postoperative wound infections.
mesh_terms: D000367:Age Factors; D000667:Ampicillin / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001414:Bacitracin / Q000627:therapeutic use; D002509:Cephaloridine / Q000627:therapeutic use; D048909:Diabetes Complications; D004322:Drainage / Q000009:adverse effects; D005932:Gloves, Surgical; D006168:Guinea Pigs; D006582:Hexachlorophene / Q000627:therapeutic use; D006801:Humans; D007422:Intestines / Q000382:microbiology; D007612:Kanamycin / Q000627:therapeutic use; D007902:Length of Stay; D009355:Neomycin / Q000627:therapeutic use; D009748:Nutrition Disorders / Q000150:complications; D009765:Obesity / Q000150:complications; D010406:Penicillins / Q000627:therapeutic use; D013203:Staphylococcal Infections / Q000517:prevention & control; D013530:Surgical Wound Infection / Q000209:etiology* / Q000517:prevention & control; D014466:Ultraviolet Rays
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D001414:Bacitracin; D007612:Kanamycin; D000667:Ampicillin; D009355:Neomycin; D006582:Hexachlorophene; D002509:Cephaloridine