title: Radiologic-pathologic correlations in laryngeal carcinoma.
abstract: Radiological examinations are a prerequisite for accurate assessment of laryngeal tumors, especially when contemplating partial (voice conservation) surgery. The clinical assessments and preoperative radiographs from five cases have been compared with the histologic findings in whole organ serial sections of the laryngectomy specimens. These studies demonstrated both the accuracies and the deficiencies of the present clinical and radiologic examination methods. The mucosal extension of tumor is accurately assessed by a combination of direct laryngoscopy and radiography. The latter mainly gives information concerning the vertical extent of tumor, especially contrast laryngography. Xeroradiography may give additional information. Deep invasion of tumor with cartilage destruction and spread outside the larynx is often not assessable preoperatively. Circumferential and symmetrical lesions may be missed radiologically as much of the interpretation is based on asymmetry. New methods must be developed to assess the deep invasion of tumor. The necessity of a close liaison between the laryngologist, radiologist, and clinical pathologist is stressed.
mesh_terms: D000368:Aged; D006801:Humans; D007400:Interprofessional Relations; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery / Q000628:therapy; D007825:Laryngectomy; D007828:Laryngoscopy; D008297:Male; D008722:Methods; D014056:Tomography, X-Ray; D014986:Xeroradiography