Severe hemolysis with a fabric-worn cloth-covered aortic valve prosthesis.
A patient developed severe hemolytic anemia one year after insertion of a cloth-covered aortic valve prosthesis (Starr-Edwards No. 2320). The cloth over the three struts was disrupted but showed coverage with mostly organized collagen. Hemolysis stopped after replacement with a porcine heterograft. Fabric wear seems to augment the hemolysis in patients with cloth-covered artificial valves.
D000328:Adult; D000743:Anemia, Hemolytic / Q000209:etiology*; D000818:Animals; D001021:Aortic Valve / Q000637:transplantation; D001024:Aortic Valve Stenosis / Q000601:surgery; D003094:Collagen / Q000502:physiology; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006461:Hemolysis; D006801:Humans; D008297:Male; D011474:Prosthesis Design; D013552:Swine; D014183:Transplantation, Heterologous
D003094:Collagen