Evidence for macrophage C3d-receptor active in phagocytosis.
Evidence is presented that guinea pig peritoneal macrophages possess membrane receptors able to recognize the C3b inactivator-cleaved third component of complement. This conclusion is based on the finding that rosette formation and phagocytosis by macrophages of EA-IgM-C1423 were equal regardless of whether EA-IgM-C1423 had been pretreated with C3b inactivator or not.
D000818:Animals; D000906:Antibodies; D001202:Ascitic Fluid / Q000166:cytology; D001665:Binding Sites; D003165:Complement System Proteins; D004912:Erythrocytes / Q000276:immunology; D006098:Granulocytes / Q000276:immunology; D006168:Guinea Pigs; D006801:Humans; D007104:Immune Adherence Reaction; D007075:Immunoglobulin M; D008264:Macrophages / Q000276:immunology*; D010587:Phagocytosis
D000906:Antibodies; D007075:Immunoglobulin M; D003165:Complement System Proteins