Maternal thyroid status and the incidence of respiratory distress syndrome: evaluation of a proposed relationship.
In order to establish whether maternal thyroid hormones cross the placenta and produce surfactant in the fetus, possibly reducing the incidence of respiratory distress syndrome (RDD), a retrospective analysis of low-birthweight infants was undertaken. Results indicate that maternal thyroid hormones play a negligible role and that any thyroid mediation would result from fetal thyroid activity.
D001724:Birth Weight; D005260:Female; D005865:Gestational Age; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications; D007037:Hypothyroidism / Q000150:complications; D007231:Infant, Newborn; D007455:Iodine / Q000097:blood; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology*; D012189:Retrospective Studies; D013963:Thyroid Hormones / Q000502:physiology*; D013974:Thyroxine / Q000097:blood*
D013963:Thyroid Hormones; D007455:Iodine; D013974:Thyroxine