Transplantation antigens in Crohn's disease: Linkage of associated ankylosing spondylitis with HL-Aw27.
The complete HL-A antigen profile was examined in 77 patients with Crohn's disease,11 of whom had unequivocal ankylosing spondylitis. There was no significant difference in the frequencies of the HL-A antigens between these 77 patients and 600 normal controls. 10 male patients with Crohn's disease possessed HL-Aw27; all of these had unequivocal ankylosing spondylitis. This antigen may, therefore, be a useful marker of spondylitis in Crohn's disease.
D003424:Crohn Disease / Q000150:complications* / Q000235:genetics; D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006649:Histocompatibility Antigens; D006801:Humans; D008297:Male; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000235:genetics
D006680:HLA Antigens; D006649:Histocompatibility Antigens