Oxprenolol and hydrallazine in the treatment of hypertension.
Oxprenolol and hydrallazine in combination were found to be as effective as methyldopa in a trial in hypertensive patients. The drugs could be given in a twice-daily dosage and had a much higher degree of patient acceptance. The side effects of this drug combination were usually due to hydrallazine and were mild and short-lived, but did require the withdrawal of one patient from the trial. Hydrallazine should be used with caution in the treatment of patients with a history of myocardial lschaemia.
D000328:Adult; D004232:Diuretics / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006830:Hydralazine / Q000009:adverse effects / Q000627:therapeutic use*; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008750:Methyldopa / Q000627:therapeutic use; D008875:Middle Aged; D010096:Oxprenolol / Q000009:adverse effects / Q000627:therapeutic use*
D004232:Diuretics; D006830:Hydralazine; D010096:Oxprenolol; D008750:Methyldopa