Spinal cord compression due to extramedullary hematopoiesis in homozygous thalassemia. Case report.
The authors report a case of homozygous thalassemia in which a mass of hematopoietic tissue in the vertebral canal caused spastic paraparesis. Surgical removal of the tissue plus radiotherapy were successful. The pathological findings indicated direct extension of hematopoietic tissue from the adjacent bone marrow into the epidural space of the vertebral canal.
D000328:Adult; D006410:Hematopoiesis; D006720:Homozygote; D006801:Humans; D007796:Laminectomy; D008297:Male; D010243:Paralysis / Q000209:etiology; D013115:Spinal Canal / Q000473:pathology* / Q000601:surgery; D013117:Spinal Cord Compression / Q000209:etiology* / Q000532:radiotherapy / Q000601:surgery; D013789:Thalassemia / Q000150:complications / Q000235:genetics / Q000473:pathology*