[A cytochemical study of the dynamics of RNA synthesis as revealed in the metaphase chromosomes of HeLa cells].
The rate of DNA and RNA synthesis was determined by autoradiography using selective procedure for obtaining large numbers of mitotic HeLa cells. It was shown that RNA which was resistant in situ to ribonuclease in solutions of high ionic strength was synthesized mainly at the end of the G1 period and the first part of the S period. The synthesis of RNAse-resistant RNA was not detected at the G2 period and during mitosis.
D001345:Autoradiography; D002875:Chromosomes / Q000378:metabolism; D004273:DNA, Neoplasm / Q000096:biosynthesis; D005260:Female; D006367:HeLa Cells; D006651:Histocytochemistry; D006801:Humans; D008938:Mitosis; D012334:RNA, Neoplasm / Q000096:biosynthesis*; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D004273:DNA, Neoplasm; D012334:RNA, Neoplasm; D014316:Tritium; D013936:Thymidine
Tsitokhimicheskoe issledovanie dinamiki sinteza RNK, vyiavliaemoĭ v metafaznykh khromosomakh kletok HeLa