title: Cholescintigraphy with 99mTc-penicillamine.
abstract: D-pencillamine labeled with 99mTc (Tc-Pen) was used for cholescintigraphy in dogs and man. Satisfactory images of the gallbladder were obtained using a scintillation camera fitted with a pinhole collimator. The results of cholescintigraphy and contrast cholecystography compared favorably. The authors suggest that Tc-Pen is taken up by the hepatocytes and excreted into the bile canaliculi which enter the gallbladder. Tc-Pen may prove to be an ideal agent for evaluation of hepatocellular function.
mesh_terms: D000818:Animals; D001660:Biliary Tract Diseases / Q000175:diagnosis*; D002765:Cholecystography; D002769:Cholelithiasis / Q000175:diagnosis; D004285:Dogs; D005705:Gallbladder Diseases / Q000175:diagnosis; D006801:Humans; D007700:Kinetics; D010396:Penicillamine / Q000378:metabolism; D011877:Radionuclide Imaging; D013667:Technetium / Q000378:metabolism
chemical_list: D013667:Technetium; D010396:Penicillamine