Free autogenous grafts into the penile cavernous tissue. An experimental study in dogs.
The behaviour of free autogenous fat, dermofat, and dermo grafts in the penile cavernous tissue was studied experimentally in dogs. Dermo-fat grafts were those most easily maipulated during surgery and allowed perfect haemostasis. All the grafts were gradually replaced by fibrous tissue causing subsequent scarring and contraction. This reaction was least noticeable with dermis grafts. Cavernous transformation of the adipose tissue was not observed. For the surgical correction of Peyronie's disease the use of a dermo-fat graft is suggested. The grafts should be slightly larger than necessary to allow for the subsequent fibrosis, and the layer of fat should be kept very thin.
D000273:Adipose Tissue / Q000378:metabolism / Q000637:transplantation*; D000818:Animals; D004285:Dogs; D005990:Glycerol / Q000378:metabolism; D066298:In Vitro Techniques; D008297:Male; D010411:Penile Induration / Q000601:surgery*; D010413:Penis / Q000601:surgery*; D016038:Skin Transplantation; D013997:Time Factors; D014182:Transplantation, Autologous
D005990:Glycerol