Treatment of hyperparathyroidism by percutaneous embolization of a mediastinal adenoma.
Percutaneous embolization of parathyroid adenomas was attempted in three hypercalcemic patients with previously unsuccessful neck explorations. Two adenomas were in the mediastinum and the third was within the thyroid lobe. Autologous clot, Gelfoam, and silicone rubber were used to obstruct feeding arteries. The intrathyroidal adenoma failed to respond but both mediastinal adenomas were infarcted. Hyperparathyroidism recurred after 7 months in one patient but the other remains normocalcemic 8 months postembolization.
D000236:Adenoma / Q000000981:diagnostic imaging / Q000628:therapy*; D000328:Adult; D000792:Angiography; D001777:Blood Coagulation; D004617:Embolism; D005260:Female; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use; D006801:Humans; D006961:Hyperparathyroidism / Q000628:therapy*; D008297:Male; D008323:Mammary Arteries / Q000000981:diagnostic imaging; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D008875:Middle Aged; D010280:Parathyroid Glands / Q000098:blood supply; D010281:Parathyroid Hormone / Q000097:blood; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D012008:Recurrence; D012826:Silicone Elastomers; D013961:Thyroid Gland / Q000098:blood supply; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy
D010281:Parathyroid Hormone; D012826:Silicone Elastomers