[Effect of sodium ribonucleate on amino acid acceptance by transport RNA in the rabbit liver and muscles].
Both single or repeated (during 14 days) administration of sodium ribonucleate (10 mg/kg) into rabbits, caused an increased formation of lysine-RNA, leucine-t-RNA and alanine-t-RNA; At the same time, the acceptive capacity of t-RNA and aminoacylating activity of amino acyl-t-RNA-synthetases were increased. In sceletal muscles these processes were unaltered after single administration of sodium ribonucleate, but were stimulated after the repeated injections.
D000215:Acylation; D000586:Amination; D000596:Amino Acids / Q000378:metabolism*; D000604:Amino Acyl-tRNA Synthetases / Q000302:isolation & purification; D000818:Animals; D001667:Binding, Competitive; D002250:Carbon Radioisotopes; D002848:Chromatography, DEAE-Cellulose; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D009132:Muscles / Q000187:drug effects* / Q000378:metabolism; D012313:RNA / Q000494:pharmacology*; D012343:RNA, Transfer / Q000302:isolation & purification / Q000378:metabolism*; D011817:Rabbits; D012964:Sodium; D013053:Spectrophotometry; D015003:Yeasts
D000596:Amino Acids; D002250:Carbon Radioisotopes; D012313:RNA; D012343:RNA, Transfer; D012964:Sodium; D000604:Amino Acyl-tRNA Synthetases
Vliianie ribonukleata natriia na aktseptirovanie aminokislot transportnymi RNK v pecheni i myshtsakh krolikov