Complement fixing and lymphocytotoxic antibodies in serum of pregnant women at delivery. IV. Serology.
The paper concerns 275 sera of pregnant women at delivery containing complement fixing platelet antibodies (CFPAb) and/or lymphocytotoxic antibodies (LCTAb). 79 sera contained operationally monospecific antibodies against platelets and/or lymphocytes. 10 sera had only CFPAb, 4 of these were C-fix anti-A. 41 sera had CFPAb and LCTAb, 18 of these were monospecific against platelets and/or lymphocytes. In 224 sera only LCTAb could be demonstrated, 57 were monospecific. Furthermore in 8 of 258 primigravidae, screened for LCTAb 6 months post partum antibodies were detected. Generally the antibodies present at delivery had disappeared or narrowed, but in 3 cases the antibodies were detectable only in the postpartum sample.
D000906:Antibodies / Q000032:analysis*; D000918:Antibody Specificity; D001787:Blood Group Incompatibility; D001792:Blood Platelets / Q000276:immunology*; D003168:Complement Fixation Tests; D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D005331:Fetomaternal Transfusion; D006649:Histocompatibility Antigens; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D010298:Parity; D011247:Pregnancy
D000906:Antibodies; D006649:Histocompatibility Antigens