Immunosuppressive anticancer drugs in man: their oncogenic potential.
As therapy of cancer becomes more sucessful, the number of long-term survivors is increasing. In addition, cancer chemotherapeutic drugs are being used as immunosuppressive agents in the chronic treatment of non-neoplastic diseases. The long-range hazards of therapy are a serious consideration in these two groups of patients. This brief review examines the potential oncogenic as well as co-oncogenic hazards of cancer chemotherapy in man. Many of these drugs are oncogenic and/or co-oncogenic in experimental animals.
D000970:Antineoplastic Agents / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D009369:Neoplasms / Q000139:chemically induced*; D009381:Neoplasms, Radiation-Induced; D011878:Radiotherapy / Q000009:adverse effects
D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents