title: The effects of chronic ventricular pacing on the human conduction system.
abstract: Six cardiac patients had His bundle electrograms obtained prior to ventricular pacing. Hours to days after constant pacing, repeat His bundle electrograms were obtained. The H-Q interval increased after pacing in 5 of the 6 patients. The average H-Q interval of 55.8 msec increased to the post pacing value of 67.5 msec (p smaller 0.02). Thus ventricular pacing can produce a conduction delay in the His Purkinje system.
mesh_terms: D001145:Arrhythmias, Cardiac / Q000503:physiopathology / Q000628:therapy*; D002036:Bundle of His / Q000503:physiopathology; D004562:Electrocardiography; D006327:Heart Block / Q000503:physiopathology / Q000628:therapy; D006329:Heart Conduction System / Q000503:physiopathology; D006801:Humans; D010138:Pacemaker, Artificial / Q000009:adverse effects*; D011690:Purkinje Fibers / Q000503:physiopathology; D013997:Time Factors