title: Localized scleroderma.
abstract: Familial scleroderma is rare; only seven documented instances of the disease have been reported, to our knowledge. This report adds two more families to the literature. Three children in one family and two in the other had clinically and histiologically established localized scleroderma.
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008297:Male; D012594:Scleroderma, Localized / Q000188:drug therapy / Q000235:genetics*
chemical_list: D006886:Hydroxychloroquine