An endoscopic method for recording DC potentials in the upper gastrointestinal tract.
An endoscopic sensing electrode for measuiring mucosal potential differences along the duodenum, stomach and esophagus is described. Potential profiles were plotted for 31 humans. The profiles of 11 patients with documented carcinoma differed in shape from the profiles of 20 reference subjects with no such documentiation. The profiles of all the reference subjects demonstrated a distinct concave shape with a single pronounced dip. On the other hand, carcinoma profiles did not manifest such a dip but were flattened out and/or manifested an undulatory trend.
D000328:Adult; D000368:Aged; D000669:Amplifiers, Electronic; D002277:Carcinoma / Q000503:physiopathology; D004068:Digestive System Physiological Phenomena; D004386:Duodenum / Q000502:physiology; D004553:Electric Conductivity; D004566:Electrodes; D004724:Endoscopy / Q000379:methods; D004947:Esophagus / Q000502:physiology; D005753:Gastric Mucosa / Q000502:physiology; D005756:Gastritis / Q000503:physiopathology; D005770:Gastrointestinal Neoplasms / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D010437:Peptic Ulcer / Q000503:physiopathology; D011127:Polyps / Q000503:physiopathology; D011199:Potentiometry / Q000295:instrumentation / Q000379:methods*; D013270:Stomach / Q000502:physiology