title: Characteristics of CA1 neurons recorded intracellularly in the hippocampal in vitro slice preparation.
abstract: Intracellular recordings were made from CA1 pyramidal cells in the hippocampal in vitro slice preparation. Neurons displayed characteristics previously described for the intact preparation including: EPSPs, IPSPs, depolarizing after-potentials, bursting, frequency potentiation, double pulse facilitation, and probably dendritis spiking. Cells could be discharged when orthodromic or antidromic pathways were stimulated, with injection of a depolarizing current pulse, and from iontophoresis of glutamic acid. The apparently normal behavior of the neurons makes the isolated hippocampal slice a promising cortical preparation.
mesh_terms: D000200:Action Potentials; D000818:Animals; D004558:Electric Stimulation; D004566:Electrodes; D005071:Evoked Potentials; D005971:Glutamates / Q000494:pharmacology; D006168:Guinea Pigs; D006624:Hippocampus / Q000502:physiology*; D066298:In Vitro Techniques; D007478:Iontophoresis; D008564:Membrane Potentials; D013569:Synapses / Q000502:physiology
chemical_list: D005971:Glutamates