Circulating antispermatozoa immunoglobulin G in men after vasectomy.
The sera from ten vasectomized men produced immobilization and agglutination of human spermatozoa and positive passive hemagglutination tests. Immunoglobulin G fractionated from the samples of sera produced similar effects. In these men, it appears that a circulating antibody, immunoglobulin G, was produced against spermatozoa after vasectomy. The sera from 22 men who had not undergone vasectomy did not cause spermatozoa immobilization or agglutination, and produced a negative passive hemagglutination test.
D000328:Adult; D000372:Agglutination Tests; D002465:Cell Movement; D006386:Hemagglutination Tests; D006801:Humans; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000302:isolation & purification; D008297:Male; D008875:Middle Aged; D013094:Spermatozoa / Q000276:immunology*; D014659:Vasectomy
D007074:Immunoglobulin G