Vitamin D-dependent calcium-binding protein from rat kidney.
A calcium-binding protein has been partially purified from rat kidney. It is found in the cortex, but not in the medulla. It is Vitamin D-dependent, as it occurs in normal, but not in Vitamin D-deficient rats. The molecular weight is 28 000, more than twice that of the Vitamin D-dependent calcium-binding proteins from rat intestinal mucosa. The apparent dissociation constant of the partially purified renal calcium-binding protein is approx. 10-5 M.
D000818:Animals; D001665:Binding Sites; D001835:Body Weight / Q000187:drug effects; D002118:Calcium / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism; D007672:Kidney Cortex / Q000378:metabolism*; D007679:Kidney Medulla / Q000378:metabolism; D007700:Kinetics; D008970:Molecular Weight; D010710:Phosphates / Q000097:blood; D011485:Protein Binding; D011506:Proteins / Q000378:metabolism*; D051381:Rats; D011955:Receptors, Drug; D014807:Vitamin D / Q000494:pharmacology*; D014808:Vitamin D Deficiency / Q000378:metabolism*
D010710:Phosphates; D011506:Proteins; D011955:Receptors, Drug; D014807:Vitamin D; D002118:Calcium