Partial Klüver-Bucy syndrome produced by destroying temporal neocortex or amygdala.
The temporal neocortex was removed in 4 monkeys, and 5 received amygdala destruction.  Four control animals received skin and muscle incisions.  The monkeys were compared on a visual pattern discrimination task, a food-non-food discrimination, and a rating scale that measured agonistic and approach behavior.  Only the cortical lesion disrupted retention of the visual pattern task and neither lesion disrupted performance of the food-non-food task.  Both lesions produced oral behavior, increased reaction to stimuli and decreased emotionality.  Thus, the major symptoms of the Klüver-Bucy syndrome are produced by destroying either the temporal neocortex or the amygdala.
D000679:Amygdala / Q000502:physiology*; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology*; D004195:Disease Models, Animal; D005260:Female; D008253:Macaca mulatta; D008297:Male; D011612:Psychosurgery / Q000009:adverse effects*; D012726:Sexual Behavior, Animal / Q000502:physiology; D013577:Syndrome; D013702:Temporal Lobe / Q000502:physiology*