Structural identification of haemoglobin E in a group of Thai subjects.
Among 1052 women from Northern Thailand whose bloods were examined for haemoglobin variants by starch gel electrophoresis, 84 (8.0 per cent) had variant with the doubly-slow mobility associated with Haemoglobin E. Seventy-nine of those slow variants were examined by chemical structure studies and all were confirmed to have the change, beta26 Glu leads to Lys, associated with Haemoglobin E. These results indicate that other variants with mobilities like that of Haemoglobin E are uncommon in Thairs.
D000328:Adult; D001800:Blood Specimen Collection; D004592:Electrophoresis, Starch Gel; D005260:Female; D014644:Genetic Variation; D006455:Hemoglobins, Abnormal / Q000032:analysis* / Q000302:isolation & purification*; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D010455:Peptides / Q000032:analysis; D013785:Thailand
D006455:Hemoglobins, Abnormal; D010455:Peptides