Direct n8-alkylation of 2,4-dihydropteridines;Preparation of 7,8-dihydro-8-methylmethotrexate.
D000478:Alkylation; D003959:Diamines; D006900:Hydroxylation; D008722:Methods; D008727:Methotrexate / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D011621:Pteridines
D003959:Diamines; D011621:Pteridines; D008727:Methotrexate