o,p'DDD therapy in invasive adrenocortical carcinoma.
Invasive adrenocortical carcinoma was diagnosed in two patients, 3 1/2 and 69 years of age, respectively. Therapy with o,p'DDD was begun immediately, and the patients have survived 4 1/12 and 7 9/12 years, respectively. The prolonged survival represents possible "cure" of inoperable disease following early initiation of therapy.
D000302:Adrenal Cortex; D000310:Adrenal Gland Neoplasms / Q000188:drug therapy* / Q000601:surgery; D000311:Adrenal Glands; D000368:Aged; D002277:Carcinoma / Q000188:drug therapy* / Q000601:surgery; D002675:Child, Preschool; D003632:Dichlorodiphenyldichloroethane / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008939:Mitotane / Q000008:administration & dosage / Q000627:therapeutic use*
D008939:Mitotane; D003632:Dichlorodiphenyldichloroethane