Artificial liver support based on haemoperfusion of adsorbents.
The need for a device capable of performing the excretory functions of the liver during acute and chronic liver failure is described. Experience of artificial liver support systems is reviewed. The results of patients treatment with adsorbent haemoperfusion are discussed and problems of system design and biocompatibility are outlined.
D000327:Adsorption; D000596:Amino Acids / Q000378:metabolism; D000641:Ammonia / Q000378:metabolism; D000818:Animals; D001187:Artificial Organs; D001647:Bile Acids and Salts / Q000378:metabolism; D001663:Bilirubin / Q000378:metabolism; D001672:Biocompatible Materials; D002606:Charcoal / Q000378:metabolism; D004285:Dogs; D007475:Ion Exchange Resins / Q000378:metabolism; D008099:Liver / Q000378:metabolism / Q000502:physiology; D008107:Liver Diseases / Q000628:therapy; D010477:Perfusion / Q000295:instrumentation / Q000379:methods*
D000596:Amino Acids; D001647:Bile Acids and Salts; D001672:Biocompatible Materials; D007475:Ion Exchange Resins; D002606:Charcoal; D000641:Ammonia; D001663:Bilirubin