Reactions of cyanomethylbenzimidazoles. Part II. Reaction of cyanomethylbenzimidazoles with aldehydes methylketones and nitroso compounds.
Position of CH2CN group in the benzimidazole system determines the activity of hydrogen atoms of CH2 group in condensation reactions. Some of the obtained compounds show high tuberculostatic activity.
D000447:Aldehydes; D000995:Antitubercular Agents / Q000138:chemical synthesis; D001562:Benzimidazoles; D055598:Chemical Phenomena; D002621:Chemistry; D007202:Indicators and Reagents; D007659:Ketones; D009570:Nitriles; D009603:Nitroso Compounds
D000447:Aldehydes; D000995:Antitubercular Agents; D001562:Benzimidazoles; D007202:Indicators and Reagents; D007659:Ketones; D009570:Nitriles; D009603:Nitroso Compounds