Serum antibody production--an invariable consequence of sensitization with dinitrochlorobenzene.
Antibodies to the dinitrophenyl determinant as estimated by a modified antigen-binding procedure have been found in the sera of all guinea pigs with contact sensitivity to DNCB. The humoral as well as the dermal responses were detectable within 7 days after immunization and persisted for at least 10 wk.
D000818:Animals; D000917:Antibody Formation; D001666:Binding Sites, Antibody; D001800:Blood Specimen Collection; D003877:Dermatitis, Contact; D004137:Dinitrochlorobenzene / Q000276:immunology*; D005260:Female; D005620:Freund's Adjuvant; D006168:Guinea Pigs; D007104:Immune Adherence Reaction; D007114:Immunization; D007457:Iodine Radioisotopes; D008297:Male; D009578:Nitrobenzenes / Q000276:immunology*; D013997:Time Factors
D004137:Dinitrochlorobenzene; D007457:Iodine Radioisotopes; D009578:Nitrobenzenes; D005620:Freund's Adjuvant