Bronchial reactivity to exercise in bronchial asthma.
In 65 asthmatics the behaviour of resistance during and following physical exercise was analyzed. There could be distinguished 3 types: I. Decrease of resistance during exercise. II. Decrease of resistance during exercise, but increase during recovery phase. III. Increase with a maximum of 8 to 15 min following exercise. The most frequent type was type II. Type III was characterized by lower initial values of FEV 1.0 and the highest relation between expiratory and inspiratory resistance. The strongest reaction to acetylcholine occurred in types II and III. The results speak in favour of the fact that vegetative irritability as well as mechanical factors are of special importance in exercise-induced asthma.
D000109:Acetylcholine; D000402:Airway Obstruction; D000403:Airway Resistance; D001249:Asthma / Q000503:physiopathology*; D005080:Exercise Test; D005541:Forced Expiratory Volume; D006801:Humans; D007545:Isoproterenol; D011941:Receptors, Adrenergic
D011941:Receptors, Adrenergic; D007545:Isoproterenol; D000109:Acetylcholine