Transformations of cannabinol in the mouse.
The in vivo transformations of cannabinol (CBN) in the mouse have been studied and a pattern of metabolism established. As with other cannabinoids, the 7 position and the side chain are hydroxylated followed by further oxidation to acidic metabolites. Two of these CBN metabolites have been isolated previously as metabolites of delta1-tetrahydrocannabinol (THC) suggesting that CBN may be a transformation product of delta1-THC.
D000818:Animals; D001711:Biotransformation; D002188:Cannabis / Q000032:analysis / Q000378:metabolism* / Q000652:urine; D002849:Chromatography, Gas; D013759:Dronabinol / Q000378:metabolism; D005243:Feces / Q000032:analysis; D008297:Male; D013058:Mass Spectrometry; D051379:Mice; D008809:Mice, Inbred C3H
D013759:Dronabinol