[Determination of chloroquine in biological material by gas-liquid chromatography (author's transl)].
A method is developed for the gas chromatographic determination of chloroquine after extraction from biological material, using medazepam as the internal standard and a column filled with 3% OV-17 on Gas-Chrom Q. The detection limits are: 0.15 mug/ml of urine, 0.25 mug/ml of whole blood, and 1.50 mug/g of tissue. The technique can be applied in toxicological analysis and in monitoring drug levels.
D002738:Chloroquine / Q000032:analysis* / Q000097:blood / Q000652:urine; D002849:Chromatography, Gas / Q000379:methods; D008472:Medazepam / Q000032:analysis; D014020:Tissue Extracts / Q000032:analysis
D014020:Tissue Extracts; D002738:Chloroquine; D008472:Medazepam
Dosage de la chloroquine dans les milieux biologiques par chromatographie en phase gazeuse