Susceptibility to mitomycin C and lecithinase activities of Clostridium oedematiens (C. novyi) type B and D.
In tests with broth-culture products of Clostridium oedematiens, none of 15 type-B strains showed beta-toxin lecithinase activities exceeding 20 egg-units per ml, whereas 12 of 13 type-D strains consistently produced much greater amounts of the lecithinase. The types also differed in their susceptibility to lysis by mitomycin C (MC). Of 13 type-D strains tested, 12 were sensitive to MC at a concentration of 1 or 2 mug per ml, whilst 14 of 15 type-B strains were insensitive. Phage-like particles were observed in the MC-lysates of some type-D strains. No type-specific differences in the production of indole or the fermentation of maltose were demonstrated.
D001433:Bacteriolysis; D001435:Bacteriophages; D003013:Clostridium / Q000145:classification* / Q000187:drug effects / Q000201:enzymology; D007211:Indoles / Q000378:metabolism; D008320:Maltose / Q000378:metabolism; D008937:Mitomycins / Q000494:pharmacology*; D010740:Phospholipases / Q000096:biosynthesis*; D013045:Species Specificity; D014118:Toxins, Biological / Q000096:biosynthesis
D007211:Indoles; D008937:Mitomycins; D014118:Toxins, Biological; D008320:Maltose; D010740:Phospholipases