Low-renin hypertension. Occurrence in vascular complications.
Two hundred one patients with essential hypertension, who had studies of their renin-aldosterone system performed between April 1967 and December 1972, were surveyed for myocardial infraction or cerebrovascular accident. Of the patients, 42% had low plasma renin activity. Myocardial infractions or cerebrovascular accidents were documented in 15% of those with low plasms renin activity and in 5% of those with normal plasma renin activity. When adjustments were made for differences in afe and blood pressure , a protective effect in low-renin hypertension was evident. When black patients were considered separately,there was no difference in diastolic blood pressure; however, vascular complications were not less frequent in low-renin hypertensives. The results suggest that low plasma renin activity does not protect against the development of vascular complications in essential hypertension.
D044383:Black People; D002561:Cerebrovascular Disorders / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications*; D009203:Myocardial Infarction / Q000453:epidemiology / Q000209:etiology*; D010414:Pennsylvania; D012083:Renin / Q000097:blood*; D012189:Retrospective Studies; D044465:White People; D001741:Black or African American
D012083:Renin