Aerobic lactate production by mammary tissue.
Glucose uptake and L-lactate production were measured in cell, slice and intact tissue preparations of mammary glands from late-pregnant and lactating rats. The tissues showed extensive conversion of glucose into lactate in vitro, but not in vivo. Therefore aerobic lactate formation is not a normal feature of mammary tissue, but occurs in vitro as the result of some metabolic derangement.
D000332:Aerobiosis; D000818:Animals; D005260:Female; D005947:Glucose / Q000378:metabolism*; D066298:In Vitro Techniques; D007773:Lactates / Q000096:biosynthesis*; D007774:Lactation; D008321:Mammary Glands, Animal / Q000378:metabolism*; D011247:Pregnancy; D051381:Rats
D007773:Lactates; D005947:Glucose