Stimulation of bone resorption in organ culture by salt-free extracts of Solanum glaucophyllum.
Addition of a desalted aqueous extract made from dried leaves of Solanum glaucophyllum produced a marked stimulation of bone resorption in a culture system in vitro. This result indicates that, like the biologically active forms of vitamin D, the active material in the plant not only stimulates intestinal calcium absorption but increases bone mobilization as well.
D000818:Animals; D000831:Animals, Newborn; D001862:Bone Resorption / Q000187:drug effects*; D001842:Bone and Bones / Q000187:drug effects / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D002132:Calcium Radioisotopes; D004305:Dose-Response Relationship, Drug; D051379:Mice; D009924:Organ Culture Techniques; D010936:Plant Extracts / Q000494:pharmacology; D010944:Plants
D002132:Calcium Radioisotopes; D010936:Plant Extracts; D002118:Calcium