Studies of the effects of blockage of intestinal lymphatics. III. Temporary isolation of lymphedematous bowel from intestinal continuity.
Eight dogs underwent intestinal lymphatic block. Once intestinal lymphedema was established, a segment was excluded from continuity for four months and then restored to continuity. The lymphedema decreased during exclusion and reappeared after restoration to continuity. The relationship of the changes seen in the intestine following lymphatic block and to the changes observed in the bowel in regional enteritis suggests a pathogenetic role for lymphatic blockage and explains the pseudobeneficial effects of by-pass as well as the prompt recrudescence of pathology which follows reconstruction procedures.
D000818:Animals; D001706:Biopsy; D004285:Dogs; D007422:Intestines / Q000033:anatomy & histology*; D008208:Lymphatic System / Q000033:anatomy & histology / Q000502:physiology*; D008209:Lymphedema / Q000209:etiology* / Q000473:pathology