Choroid plexus isografts in rats.
Choroid plexuses from adult rats were grafted to the kidneys of other rats of the same inbred strain. Almost all the grafts survived and exhibited a multiloculated pattern of choroidal papillae. Mild but progressive enlargement of the locules was probably caused by secretion of cerebrospinal fluid. Cyclophosphamide, a drug which damages the normally situated plexus, had similar but milder effects on the plexus implants. Isografts should prove useful for other studies of choroid plexus structure and function.
D000818:Animals; D002831:Choroid Plexus / Q000187:drug effects / Q000502:physiology / Q000637:transplantation*; D003520:Cyclophosphamide / Q000494:pharmacology; D006084:Graft Rejection; D007249:Inflammation / Q000139:chemically induced; D007668:Kidney; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014185:Transplantation, Isogeneic
D003520:Cyclophosphamide