[The effect of severity and duration of hemorrhagic hypotension and the narcosis on the plasma levels of lysosomal enzymes in dogs (author's transl)].
The effect of degree and duration of hemorrhagic hypotension on the lysosomal enzyme and LAP levels of plasma of the anaesthesied or wakeful dog has been examined. We ascertained that in a state of hypovolaemia a reduction by 10 mm Hg of the blood pressure resulting significantly increased enzyme activity during the same time. A similar change was caused by prolonging the time. In the anaesthesised group there was the enzyme activity after 120 min of haemorrhagic hypotension lower.
D000135:Acid Phosphatase / Q000097:blood; D000758:Anesthesia; D000768:Anesthesia, General; D000772:Anesthesia, Local; D000818:Animals; D001794:Blood Pressure; D004285:Dogs; D004798:Enzymes / Q000097:blood*; D005966:Glucuronidase / Q000097:blood; D007022:Hypotension / Q000201:enzymology*; D007931:Leucyl Aminopeptidase / Q000097:blood; D008247:Lysosomes / Q000201:enzymology*; D012771:Shock, Hemorrhagic / Q000201:enzymology*; D013997:Time Factors
D004798:Enzymes; D000135:Acid Phosphatase; D005966:Glucuronidase; D007931:Leucyl Aminopeptidase
Die Wirkung von Grad und Zeitdauer der hämorrhagischen Hypotension und der Narkose auf die lysosomalen Plasmaenzymakivitäten bei Hunden