Evaluation of myocardial contractility by the non-invasive method.
In evaluation of cardiac function by the non-invasive method, the possibility of separation of cardiac muscle performance from cardiac pump performance was studied. Among the non-invasive values, SV/ET, SV/(AO/EO), Pd/ICT, Pd/PEP, 1/ICT2, ET/PEP, and ET/ICT were considered as parameters for myocardial contractility. This research especially focused on Pd/ICT and ET/PEP. In auricular fibrillation it was possible to draw Starling-like curves and 3 dimensional coordinates to estimate a Vmax-like value. However this method could not be used in sinus rhythm. Whereas, in hypertension with abnormal afterload and uremia with abnormal preload, myocardial contractility was expressed by Pd/ICT under the influence of almost pure preload and ET/PEP under the influence of both preload and afterload. Therefore Pd/ICT was corrected with preload (AO/EO) and (Pd/ICT)/(AO/EO) may be used as the index for myocardial contractility.
D000368:Aged; D001281:Atrial Fibrillation / Q000503:physiopathology; D001794:Blood Pressure; D002302:Cardiac Output; D003864:Depression, Chemical; D004071:Digitalis Glycosides / Q000494:pharmacology; D006334:Heart Function Tests / Q000379:methods*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D009638:Norepinephrine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D014511:Uremia / Q000503:physiopathology
D004071:Digitalis Glycosides; D011433:Propranolol; D007545:Isoproterenol; D009638:Norepinephrine