Quality of spinal extradural anaesthesia: the influence of spinal nerve root diameter.
Profiles on the progress of spinal extradural anaesthesia were made in 246 patients using various concentrations of lignocaine, bupivacaine and etidocaine. The advance of analgesia through the different dermatomes showed a consistent and orderly spread on the upper lumbar and thoracic segments. This spread was irregular through the lower lumbar and upper sacral segments. The first sacral segment was especially difficult to block with an overall failure rate of 17.53% with presently available concentrations of various local anaesthetics. This failure was abolished with the use of etidocaine 1.5%. The presence of a delay or failure at the level of L5-S2 is probably related to the larger diameter of these nerve roots as ascertained from measurements in 11 cadavers.
D000083:Acetanilides / Q000008:administration & dosage / Q000031:analogs & derivatives; D000293:Adolescent; D000328:Adult; D000368:Aged; D000767:Anesthesia, Epidural; D000779:Anesthetics, Local; D002045:Bupivacaine / Q000008:administration & dosage; D003238:Connective Tissue / Q000033:anatomy & histology; D005021:Ethylamines / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage; D008161:Lumbosacral Region; D008297:Male; D008875:Middle Aged; D011437:Propylamines / Q000008:administration & dosage; D013126:Spinal Nerve Roots / Q000033:anatomy & histology*; D013900:Thoracic Nerves; D013997:Time Factors
D000083:Acetanilides; D000779:Anesthetics, Local; D005021:Ethylamines; D011437:Propylamines; D008012:Lidocaine; D002045:Bupivacaine