Lack of effect of vitamin A on differentiation in squamous carcinoma.
High oral doses of vitamin A given to Irish rats bearing squamous carcinomas failed to produce detectable light level histologic change in the tumors.  The cell line was grown in tissue culture with and without vitamin A; electron-microscopic examination failed to reveal significant differences between experimental and control cultures.
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002460:Cell Line; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D009374:Neoplasms, Experimental; D051381:Rats; D014801:Vitamin A / Q000494:pharmacology*
D014801:Vitamin A