Postexercise glycogen replenishment in untrained animals: denervation, tenotomy effects.
To test the hypothesis that an intact nerve supply is essential to normal replenishment of muscle glycogen after exhaustive exercise, glycogen concentration in normal gastrocnemius muscles from guinea pigs exhausted 48 hr previously was compared to glycogen in contralateral muscles that had been denervated at the muscle or high in the thigh immediately after exercise. Each animal of another group underwent tenotomy of one Achilles tendon after exercise so that any effect of disuse could be distinguished from effects of denervation. All muscles were able to replenish glycogen to normal control values 48 hr after exercise and surgery; there were no significant (greater than .05) effects of any of the surgical interventions. Therefore, it appears that glycogen concentration in skeletal muscle 48 hr after exhaustive exercise is independent of both neural phenomena and muscle tension.
D000818:Animals; D003714:Denervation; D005260:Female; D006003:Glycogen / Q000378:metabolism*; D006168:Guinea Pigs; D009132:Muscles / Q000294:innervation / Q000378:metabolism*; D005082:Physical Exertion; D013710:Tendons / Q000601:surgery; D013997:Time Factors
D006003:Glycogen