Treatment of coccidioidomycosis infection of bone with local amphotericin B suction-irrigation. Report of a case.
A 29-year-old man with coccidioidomycosis of the tarsal bones and toxic reactions to intravenous Amphotericin B was treated by surgical curettage and local suction-irrigation system of Amphotericin B. The patient responded to treatment and was free of disease 2 years later. Local suction-irrigation with Amphotericin B may be a valuable adjunct in the treatment of coccidioidomycosis infection of bone.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D001847:Bone Diseases / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D003045:Coccidioides / Q000302:isolation & purification; D003047:Coccidioidomycosis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D004322:Drainage; D005528:Foot / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D011859:Radiography; D013639:Tarsal Bones / Q000382:microbiology*; D007507:Therapeutic Irrigation
D000666:Amphotericin B