Failure of decreased serotonin uptake or monoamine oxidase inhibition to block the acceleration in brain 5-hydroxyindole synthesis that follows food consumption.
The acceleration in brain serotonin synthesis produced by injecting rats with tryptophan or allowing them to consume a carbohydrate diet was not blocked by the prior elevation of brain serotonin levels (by administration of a MAO inhibitor: Lilly 51641) or by a treatment (chlorimipramine administration) that decreases impulse flow along serotoninergic neurons.
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D002997:Clomipramine / Q000494:pharmacology; D004040:Dietary Carbohydrates / Q000378:metabolism*; D004435:Eating; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D007211:Indoles / Q000096:biosynthesis*; D008297:Male; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology*; D051381:Rats; D012701:Serotonin / Q000378:metabolism*; D013268:Stimulation, Chemical; D014364:Tryptophan / Q000378:metabolism / Q000494:pharmacology
D004040:Dietary Carbohydrates; D007211:Indoles; D008996:Monoamine Oxidase Inhibitors; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D014364:Tryptophan; D002997:Clomipramine