Clinico-pathological correlations in a case of traumatic pan-hypopituitarism.
A case of post-traumatic chronic pan-hypopituitarism in a 22 year old man is reported. Post-mortem examination revealed gliosis of the posterior hypothalamus, sclerosis of the neuro-hypophysis, cellular atrophy of the adenohypophysis, with relative hyperplasia of the basophil cells, atrophy of the endocrine target glands. Clinical and morphological findings are correlated and discussed.
D000293:Adolescent; D000307:Adrenal Gland Diseases / Q000209:etiology; D000328:Adult; D001930:Brain Injuries / Q000150:complications*; D003919:Diabetes Insipidus / Q000209:etiology; D004702:Endocrine Glands / Q000473:pathology; D005911:Gliosis; D006801:Humans; D007006:Hypogonadism / Q000209:etiology; D007018:Hypopituitarism / Q000150:complications / Q000209:etiology / Q000473:pathology*; D007030:Hypothalamo-Hypophyseal System / Q000473:pathology; D008297:Male; D009929:Organ Size; D012598:Sclerosis; D013787:Thalamic Nuclei / Q000473:pathology