Microbiodies in methanol-grown Candida boidinii.
Intracellular structures were observed in Candida boidinii grown in a medium containing methanol as the sole source of carbon and energy; these structures were absent in the same organism grown in the presence of glucose or ethanol. These substrate-specific structures are ultrastructurally similar to microbodies. Studies with sphaeroplast and a mutant lacking alcohol-oxidase activity indicate that the alcohol may be located in these microbodies.
D000429:Alcohol Oxidoreductases / Q000302:isolation & purification; D002175:Candida / Q000201:enzymology / Q000378:metabolism / Q000648:ultrastructure*; D003460:Crystallization; D000431:Ethanol / Q000378:metabolism; D005557:Formaldehyde; D005561:Formates; D005947:Glucose / Q000378:metabolism; D000432:Methanol / Q000378:metabolism*; D008830:Microbodies / Q000201:enzymology / Q000648:ultrastructure*; D009154:Mutation; D009940:Organoids / Q000648:ultrastructure*; D010088:Oxidoreductases / Q000302:isolation & purification
D005561:Formates; D005557:Formaldehyde; D000431:Ethanol; D010088:Oxidoreductases; D000429:Alcohol Oxidoreductases; D005947:Glucose; D000432:Methanol