[The effect of vasopressin on the excretion of magnesium and other electrolytes].
In dogs, i.v. administration of pituitrin (0.5-0.8;5.0-8.0; 50.0-80.0 med/kg) in conditions of spontaneous and water diuresis increases the renal excretion of Mg, Ca and Na. This is due to the vasopressin fraction of pituitrin as the synthetic vasopressin exerted the same effect. An increase in Mg excretion after i.p.-administration of pituitrin (1 med/100 g) was noted in rats too. In 2 week puppies administration of 1 med pituitrin did not change the urine excretion of Mg or Ca. Vasopressin is supposed to participate in the Mg metabolism regulation.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D003404:Creatinine / Q000378:metabolism; D004231:Diuresis / Q000187:drug effects; D004285:Dogs; D005260:Female; D005919:Glomerular Filtration Rate / Q000187:drug effects; D007668:Kidney / Q000378:metabolism*; D008274:Magnesium / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism; D051381:Rats; D012964:Sodium / Q000378:metabolism; D013997:Time Factors; D014667:Vasopressins / Q000494:pharmacology*; D014882:Water-Electrolyte Balance / Q000187:drug effects*
D014667:Vasopressins; D012964:Sodium; D003404:Creatinine; D008274:Magnesium; D011188:Potassium; D002118:Calcium
Vliianie vazopressina na ékskretsiiu magniia i drugikh élektrolitov.