Hypotrichosis in Miniature Poodle siblings.
Progressive hypotrichosis was detected in 2 silver male Miniature Poodle siblings at 5 weeks of age. A male and 2 female siblings had normal black coats. The sire, a 3-year-old black Miniature Poodle, and the dam, a 2-year-old silver Miniature Poodle, also had normal coats. Microscopically, the hypotrichotic skin had accumulations of keratotic debris and melanin in dilated hair canals and melanin deposits in and around inactive hair bulbs. Sex-linked or sex-limited inheritance may have been involved, inasmuch as both affected dogs were males.
D000505:Alopecia / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000235:genetics* / Q000473:pathology; D004285:Dogs; D005260:Female; D007039:Hypotrichosis / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D008297:Male; D012867:Skin / Q000473:pathology