Synthesis by conventional methods of human growth hormone peptide fragments. I.
The synthesis of two protected peptides which correspond to positions 139-146 and 147-156 of the HGH primary structure is described. These peptides prepared by the stepwise procedure, are: Boc-Phe-Lys(Z)-Gln-Thr(Bzl)-Ser(Bzl)-Lys(Z)-Phe-OMe and Boc-Asp(OBzl)-Asn-Ser(Bzl)-His(Dnp)-Asn(OBzl)-Asp(OBzl)-Ala-Leu-OBzl. All protected intermediates were isolated and characterized for homogeneity.
D000409:Alanine; D001216:Asparagine; D001224:Aspartic Acid; D005973:Glutamine; D013006:Growth Hormone; D006639:Histidine; D006801:Humans; D007930:Leucine; D008239:Lysine; D009904:Optical Rotation; D010455:Peptides / Q000138:chemical synthesis*; D010649:Phenylalanine; D012694:Serine; D013912:Threonine; D014443:Tyrosine
D010455:Peptides; D005973:Glutamine; D013912:Threonine; D001224:Aspartic Acid; D014443:Tyrosine; D012694:Serine; D010649:Phenylalanine; D006639:Histidine; D001216:Asparagine; D013006:Growth Hormone; D007930:Leucine; D008239:Lysine; D000409:Alanine