Disappearance of p-aminohippurate and inulin from plasma of newborn and adult rats.
The ability of newborn and adult rats to eliminate p-aminohippuric acid and inulin from plasma was determined. The pattern of development is similar to that observed in vitro using renal cortical slices. The fact that function increases to a peak and then declines over the developmental period while organ weight and histology mature progressively suggests a divergence of functional and antomical maturation. Inulin elimination, unlike PAH, increased over the ages tested, and is apparently more closely related to organ growth.
D000367:Age Factors; D000618:Aminohippuric Acids / Q000097:blood* / Q000378:metabolism; D000818:Animals; D000831:Animals, Newborn / Q000097:blood*; D007444:Inulin / Q000097:blood* / Q000378:metabolism; D007668:Kidney / Q000254:growth & development / Q000378:metabolism; D051381:Rats
D000618:Aminohippuric Acids; D007444:Inulin