A model of the pathways of inhaled medicaments to their receptor sites.
From controlled inhalation experiments with bronchotropic substances, it becomes clear that the 'dust model of the lungs' is inadequate in explaining the 'facts and findings' of drug inhalation. Two pathway flow charts are worked out, permitting a more specific description of the transport processes involved, in order to meet the need for a more appropriate model.
D001993:Bronchodilator Agents / Q000008:administration & dosage* / Q000097:blood / Q000494:pharmacology; D004391:Dust; D006801:Humans; D008168:Lung / Q000187:drug effects / Q000294:innervation; D008954:Models, Biological; D012123:Pulmonary Ventilation; D011955:Receptors, Drug; D012125:Respiratory Center / Q000187:drug effects; D012143:Respiratory Physiological Phenomena; D012137:Respiratory System / Q000187:drug effects; D012138:Respiratory Therapy; D012140:Respiratory Tract Diseases / Q000188:drug therapy; D014692:Ventilation-Perfusion Ratio
D001993:Bronchodilator Agents; D004391:Dust; D011955:Receptors, Drug