Dietary management of patients in chronic renal failure.
A new oral amino acid preparation was given to two groups of patients: group 1, five patients on hemodialysis; and group 2, five patients with chronic renal failure (CRF). In group 1 significant pre- and postdiet changes were: BUN 93-37 mg% (p smaller than 0.01); creatinine 13.0-9.7 mg% (p smaller than 0.001); phosphorus 6.6-4.2 mg% (p smaller than 0.05); uric acid 8.7-6.0 mg% (p smaller than 0.01); CO2 16.3-21.3 mEq/I (p smaller than 0.01); hematocrit 18.0-20.8% (p smaller than 0.05). In group 2: BUN 93-66 mg% (p smaller than 0.05); phosphorus 5.6-3.8 mg% (p smaller than 0.05); hematocrit 27.3-30.7% (p smaller than 0.05). Nitrogen balance was positive in all patients. It is concluded that this oral amino acid mixture is well-tolerated and can be utilized in CRF to attain protein anabolism.
D000136:Acid-Base Equilibrium; D000284:Administration, Oral; D000596:Amino Acids / Q000008:administration & dosage*; D001806:Blood Urea Nitrogen; D002245:Carbon Dioxide / Q000097:blood; D003404:Creatinine / Q000652:urine; D005919:Glomerular Filtration Rate; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007676:Kidney Failure, Chronic / Q000178:diet therapy*; D009584:Nitrogen / Q000378:metabolism; D010758:Phosphorus / Q000097:blood; D011188:Potassium / Q000097:blood; D006435:Renal Dialysis; D012709:Serum Albumin; D014511:Uremia / Q000628:therapy; D014527:Uric Acid / Q000097:blood / Q000652:urine
D000596:Amino Acids; D006454:Hemoglobins; D012709:Serum Albumin; D002245:Carbon Dioxide; D014527:Uric Acid; D010758:Phosphorus; D003404:Creatinine; D009584:Nitrogen; D011188:Potassium