[Synthesis and antibacterial activity in vitro of some penicillins containing the phenylcyclohexanie residue].
Some penicillins with structures similar to that of ampicillin and cyclacillin bearing the phenylcyclohexane grouping were prepared. In vitro tests of antibacterial activity showed that the introduction of this residue led to reduced activity in comparison with that of the parent compound.
D000667:Ampicillin / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D003493:Cyclacillin / Q000138:chemical synthesis* / Q000494:pharmacology; D003510:Cyclohexanes; D004353:Drug Evaluation, Preclinical; D010406:Penicillins / Q000138:chemical synthesis* / Q000494:pharmacology
D003510:Cyclohexanes; D010406:Penicillins; D003493:Cyclacillin; D000667:Ampicillin
Sintesi e attività antibatterica in vitro di alcune penicilline contenenti il residuo fenilcicloesanico