An operation for partial closure of an epiphysial plate in children, and its experimental basis.
In two cases of partial closure of epiphysial causing angular deformity, one of a finger and one of the lower end of a femur, the deformities were corrected by growth after resection of a small peripheral bone bridge and its replacement with a free transplant of fat. This procedure has a firm basis on experimental work. Thus, when part of a growth plate in the rabbit is destroyed but the formation of a bone bridge uniting epiphysis and metaphysis is prevented, the destroyed part is replaced by regeneration of cartilage from the adjacent parts of the plate. Moreover, it has been proved in rabbits that when a bone bridge is induced and later resected and replaced with fat, recurrence of the bridge can be prevented and subsequent growth may correct the deformity.
D000273:Adipose Tissue / Q000637:transplantation; D000293:Adolescent; D000818:Animals; D001848:Bone Diseases, Developmental / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D001861:Bone Regeneration; D002675:Child, Preschool; D004838:Epiphyses / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005264:Femoral Fractures / Q000150:complications; D005383:Finger Injuries / Q000150:complications; D006801:Humans; D008297:Male; D011817:Rabbits; D011859:Radiography; D014182:Transplantation, Autologous