Inhibition of diuresis in the tsetse fly (Glossina morsitans) by ouabain and acetazolamide.
Acetazolamide and ouabain, metabolic inhibitors which interfere with certain membrane transport systems, reduce the rate of water elimination by male Glossina morsitans morsitans. The results suggest that water is transported across membranes during diuresis and that a ouabain sensitive Na+K+ATPase and an acetazolamide-sensitive carbonic anhydrase are involved in diuresis.
D000086:Acetazolamide / Q000494:pharmacology*; D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D003864:Depression, Chemical; D004231:Diuresis / Q000187:drug effects*; D008297:Male; D010042:Ouabain / Q000494:pharmacology*; D013997:Time Factors; D014370:Tsetse Flies / Q000187:drug effects / Q000378:metabolism*; D014867:Water / Q000378:metabolism
D014867:Water; D010042:Ouabain; D000086:Acetazolamide