Schizophrenia and Cushing's syndrome cured by adrenalectomy.
A case of Cushing's syndrome in a woman aged 50 years is described, with psychosis of schizophrenic type.  The psychosis and endocrine disorder were subsequently cured by adrenalectomy.  Twenty-five years previously the patient had a typical schizophrenic psychosis treated in mental hospital with a deep insulin therapy and ECT.  The possibility is raised that deep insulin therapy could have induced the Cushing's syndrome through its non-specific stressor effect on the pituitary-adrenal axis.
D000315:Adrenalectomy; D000308:Adrenocortical Hyperfunction / Q000209:etiology; D003295:Convulsive Therapy / Q000009:adverse effects; D003480:Cushing Syndrome / Q000150:complications / Q000209:etiology / Q000601:surgery*; D004565:Electroconvulsive Therapy / Q000009:adverse effects; D005260:Female; D006801:Humans; D008875:Middle Aged; D012075:Remission, Spontaneous; D012563:Schizophrenia, Paranoid / Q000150:complications / Q000628:therapy*