Antimitotic activity of saponin fractions and extracts from RX. primulae, RX. saponariae and Sem. Hippocastani.
The strongest biological activity in the Allium test was shown by Rx. Primulae. The inhibition of the linear growth of the onion roots affected with the extract from 0-2 g of Rx Primulae in 100 ml of water (W0-2) and with the 0-05% solution (S0-05) of the saponin fraction after 24 hrs was about 70% of the blanc halves. The inhibition of mitose affected with W0-2 and S0-05 was 90% and 80% respectively.
D008938:Mitosis / Q000187:drug effects*; D010936:Plant Extracts / Q000032:analysis*; D010944:Plants / Q000032:analysis*; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*
D010936:Plant Extracts; D012503:Saponins