Unit-dose assay of tropine alkaloids and their synthetic analogs.
A charge-transfer spectrophotometric method was developed for unit-dose assay of the tropine alkaloids and some of their synthetic analogs. The high molar absorptivities of the charge-transfer bands of the alkaloids with iodine in ethylene dichloride resulted in improved recoveries and good precision, particularly at the low dose levels of pediatric and hypodermic tablets.
D001285:Atropine / Q000032:analysis; D001286:Atropine Derivatives / Q000032:analysis; D008722:Methods; D012602:Scopolamine Derivatives / Q000032:analysis; D013056:Spectrophotometry, Ultraviolet; D013607:Tablets / Q000032:analysis; D014326:Tropanes / Q000032:analysis*
D001286:Atropine Derivatives; D012602:Scopolamine Derivatives; D013607:Tablets; D014326:Tropanes; D001285:Atropine