Automated procedure for determination of free aromatic amine in water-soluble radiopaques.
The determination of free aromatic amine in water-soluble radiopaques by diazotization in 2-methoxyethanol-water, coupling with naphthylethylenediamine, and colorimetry of the azo dye has been automated. Sensitivity, precision, and accuracy are satisfactory for purity testing and stability studies.
D000588:Amines / Q000032:analysis*; D001322:Autoanalysis; D003287:Contrast Media / Q000032:analysis*; D008722:Methods
D000588:Amines; D003287:Contrast Media