The removal and metabolism of prostaglandin E-1 by rabbit lung.
In isolated rabbit lung preparations perfused with tritiated PGE-1, it was found that, (1) PGE-1, is rapidly and almost completely metabolized during perfusion through rabbit lung. (2) During perfusion, there is no net uptake of PGE-1. (3) The process of metabolism of PGE-1 in the rabbit lung is inhibited by hypothermia.
D000818:Animals; D008168:Lung / Q000378:metabolism*; D010477:Perfusion; D011458:Prostaglandins E / Q000378:metabolism*; D011817:Rabbits; D013696:Temperature
D011458:Prostaglandins E