Diabetic capillaropathy.
Diabetic capillaropathy is defined and reviewed. A number of physiological and pathological variables, such as aging, venous stasis, and environment, may affect the thickness of the capillary basal lamina. Since these effects have not been adequately measured, it is impossible to know precisely what increment diabetes mellitus adds to the basal lamina. Because of these variables and technical difficulties, the detection of early diabetes is impossible at this time. However, the ultrastructure of the peripheral capillaries in the late stages of diabetes provides a means of detecting the presence of widespread capillaropathy when clinical evidence is difficult to obtain or uncertain.
D000375:Aging; D000818:Animals; D001485:Basement Membrane / Q000648:ultrastructure; D001707:Biopsy, Needle; D002196:Capillaries / Q000648:ultrastructure; D003925:Diabetic Angiopathies / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D004032:Diet; D004285:Dogs; D004777:Environment; D006801:Humans; D008854:Microscopy, Electron; D009132:Muscles / Q000473:pathology; D051381:Rats; D013924:Thrombophlebitis / Q000473:pathology