Experimental cervical myelopathy. Effects of ischemia and compression of the canine cervical spinal cord.
The authors report experiments designed to test the effect of regional ischemia induced by selective vascular ligations and anterior compression of the cervical cord at two adjacent segments (C-4, C-5) in the same dog. They conclude that local ischemia of the cervical cord, caused by local deformation, when superimposed on a regional reduction in spinal cord blood flow, accounts for the myelopathy of cervical spondylosis whether produced experimentally in animals or occurring naturally in man.
D000818:Animals; D003711:Demyelinating Diseases / Q000473:pathology; D004285:Dogs; D005260:Female; D007511:Ischemia / Q000503:physiopathology*; D012039:Regional Blood Flow; D013116:Spinal Cord / Q000098:blood supply* / Q000473:pathology; D013117:Spinal Cord Compression / Q000503:physiopathology*; D013118:Spinal Cord Diseases / Q000473:pathology / Q000503:physiopathology*; D013128:Spinal Osteophytosis / Q000503:physiopathology