Influence of ICRF 159 and trition WR 1339 on metastases of a rat epithelioma.
ICRF 159 and Triton WR 1339 have been examined for their ability to suppress subcutaneous growth and pulmonary metastases from a transplanted rat epithelioma. Neither compound influenced subcutaneous tumour development or reduced the propensity to metastasize when administered in regimens reported to suppress pulmonary, lymph node or intracerebral metastases in other experimental system.
D000818:Animals; D005260:Female; D008175:Lung Neoplasms / Q000473:pathology / Q000517:prevention & control; D009362:Neoplasm Metastasis / Q000517:prevention & control*; D009374:Neoplasms, Experimental / Q000517:prevention & control; D010879:Piperazines / Q000627:therapeutic use*; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D000644:Quaternary Ammonium Compounds / Q000627:therapeutic use*; D051381:Rats; D011929:Razoxane / Q000627:therapeutic use*
D010879:Piperazines; D000644:Quaternary Ammonium Compounds; D011092:Polyethylene Glycols; D011929:Razoxane