Hepatitis Bs antigen and liver cancer: A population based study in Kenya.
Peers and Linsell (1973) demonstrated a significant association between the incidence of primary liver cancer and ingested aflatoxin in a study in the Muranga district of Kenya. A study of hepatitis B antigen in the same district showed no significant differences between the low altitude area, with a relatively high incidence of primary liver cancer, and the high altitude area with a lower incidence of the tumour. Current evidence is more in favour of aflatoxin playing an important role in the aetiology of primary liver cancer but hepatitis B antigen may play an ancillary role.
D000293:Adolescent; D000328:Adult; D000348:Aflatoxins / Q000633:toxicity; D000367:Age Factors; D000531:Altitude; D002648:Child; D002675:Child, Preschool; D005260:Female; D006511:Hepatitis B Antigens / Q000032:analysis*; D006801:Humans; D007223:Infant; D007630:Kenya; D008113:Liver Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000276:immunology; D008297:Male; D012737:Sex Factors
D000348:Aflatoxins; D006511:Hepatitis B Antigens