[Esterase XX. Disc-electrophoretic investigations on the polymorphism of the esterases of the house mouse (author's transl)].
For the further clarification of the polymorphism of mouse-esterase and its hormonal control, which in part have not yet been fully comprehended, disc-electrophoretic analyses of eight organs were made, using a strain with the Tfm-mutation. In addition, quantitative assays of esterase activity as well as histochemical studies were performed. The individual organs are characterized by a specific banding pattern of esterase, which is essentially conditioned by the diverse activity of a limited number of bands. Partly these may be regarded as primary gene products, partly they seem to be secondary modifications. The few incidences of band-linkage justify the expectations, that further gene loci will be discovered. In four organs of Tfm-mutants a lower esterase activity was found than in the controls, which was especially distinct in the kidney. The behaviour of the testosterone-dependent bands in the kidneys of Tfm-mutants seems to indicate two different mechanisms of the effect of testosterone on these bands.
D000818:Animals; D001921:Brain / Q000201:enzymology; D003964:Diaphragm / Q000201:enzymology; D004386:Duodenum / Q000201:enzymology; D004589:Electrophoresis, Disc; D004950:Esterases / Q000032:analysis*; D005260:Female; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008168:Lung / Q000201:enzymology; D008297:Male; D051379:Mice; D009154:Mutation; D011110:Polymorphism, Genetic; D013363:Submandibular Gland / Q000201:enzymology; D013737:Testis / Q000201:enzymology; D013739:Testosterone
D013739:Testosterone; D004950:Esterases
Esterase. XX. Diskelektrophoretische Untersuchungen zum Polymorphismus der Esterasen der Hausmaus