[Serum concentration of glycosides and digitalis intoxication(author's transl)].
Serum glycoside concentration was 2.3 ng/ml or more in 299 patients digitalised with digoxin or digoxin derivatives. Mean serum glycoside concentration was 3.4 +/- 1.3 ng/ml (range 2.3-11.00 ng per ml). Usually, high serum concentrations were associated with advanced den or digoxin-derivative overdosage occurred in only 10% of patients. Almost three quarters of those with intoxication had impaired renal function. There was some evidence that low body-weight increased the potential risk of intoxication.
D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D001835:Body Weight; D004077:Digoxin / Q000031:analogs & derivatives / Q000097:blood / Q000506:poisoning*; D006327:Heart Block / Q000139:chemically induced; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D013610:Tachycardia / Q000139:chemically induced
D004077:Digoxin
Serumglykosidkonzentration und Digitalisintoxikation