Fatal pulmonary involvement in dermatomyositis.
A 12-year-old boy with classic dermatomyositis developed a rapidly progressive pulmonary process that led to his death a month later. Physiologically, there was interference with the oxygenation of the blood even when 100% oxygen was delivered to the lungs under pressure. Microscopic examination of the lungs disclosed diffuse interstitial pulmonary fibrosis. We conclude that these pulmonary changes were a component of the basic disease.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001996:Bronchopneumonia / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D002648:Child; D003882:Dermatomyositis / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D003951:Diagnostic Errors; D004381:Duodenal Ulcer / Q000150:complications; D005110:Extracellular Space / Q000032:analysis; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D009132:Muscles / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D011658:Pulmonary Fibrosis / Q000097:blood / Q000209:etiology*; D011859:Radiography; D012867:Skin / Q000473:pathology
D000900:Anti-Bacterial Agents; D011241:Prednisone