An animal model of radionuclide venography.
Experimental venous thrombi were created in 19 dogs, using either thrombin or sodium morrhuate. Eighteen thrombi (95%) were identified by radionuclide venography; however, an 85% false-positive rate was found when nonoperated limbs were studied. The models employed were considered unsuitable for studying the accuracy of labeled particles in diagnosing deep venous thrombosis for the reasons discussed in the text.
D000418:Albumins; D000818:Animals; D003287:Contrast Media; D004195:Disease Models, Animal; D004285:Dogs; D005189:False Positive Reactions; D005260:Female; D008297:Male; D010690:Phlebography / Q000379:methods* / Q000592:standards; D013667:Technetium; D013924:Thrombophlebitis / Q000000981:diagnostic imaging*
D000418:Albumins; D003287:Contrast Media; D013667:Technetium