Disseminated intravascular coagulation and head injury.
Blood coagulation tests were performed on admission to the hospital and on consecutive days after severe and moderate head injury in 34 patients. Platelet counts and fibrinogen were normal at admission and raised thereafter. The partial thromboplastin time was shortened at admission and lengthened in the following days. Fibrinolytic activity was enhanced at admission. The ethanol gelation test was negative in all patients during the post-traumatic time course. It was concluded that, in the first 24 hours after injury, activated coagulation was present after head injury. In contrast with data of other authors, disseminated intravascular coagulation did not occur in these series.
D001772:Blood Cell Count; D001780:Blood Coagulation Tests; D001792:Blood Platelets; D006259:Craniocerebral Trauma / Q000097:blood / Q000150:complications*; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000209:etiology*; D005165:Factor V / Q000032:analysis; D005337:Fibrin / Q000031:analogs & derivatives / Q000097:blood; D005340:Fibrinogen / Q000032:analysis; D005342:Fibrinolysis; D006801:Humans; D011517:Prothrombin Time; D013917:Thrombin / Q000032:analysis; D013925:Thromboplastin / Q000032:analysis
D005165:Factor V; D005337:Fibrin; D005340:Fibrinogen; D013925:Thromboplastin; D013917:Thrombin