Model of the antimicrobial silver uracil.
A model is proposed for the antimicrobial agent, silver uracil, whereby silver interacts with uracil forming a silver uracil combination with the silver in the +1 state intercalating between stacked uracils in a manner similar to a 'sandwich' model. The uracils maintain stability by hydrogen bonding with the water solvent, and 'flip-flop' through an antiparallism mode at 220 degrees. The silver bonds to the uracil by a charge transfer mechanism, increasing the nuclear shielding field of the pyrimidine. The presence of the water (solvent) is necessary for the structure.
D000900:Anti-Bacterial Agents; D008958:Models, Molecular; D008968:Molecular Conformation; D012834:Silver; D014498:Uracil
D000900:Anti-Bacterial Agents; D012834:Silver; D014498:Uracil