[Pyrazino(1,2-a)- and 1,4-diazepino(1,2-a)- indoles. III. Synthesis of pyrrolo(2',1':3,4)pyrazino(1,2-a)indoles and pyrrolo(2',1':3,4)-1,4-diazepino(1,2-a) indoles; isoindolo(2',1':3,4)pyrazino(1,2-a)-indoles and isoindolo(2',1':3,4)-1,4-diazepino(1,2-a)indoles; pyrazino(3,2,1-jk)- carbazoles and 1,4-diazepino(3,2,1-jk) carbazoles].
Pyrrolo(2',1':3,4)pyrazino (or 1,4-diazepino) (1,2-a)indoles and isoindolo(2',1':3,4)pyrazino (or 1,4-diazepino) (1,2-a)indoles were synthesized by reaction of 1-(2-aminoethyl)indole or 1-(3-aminopropyl)indole with gamma-keto and o-acylbenzoic acids. In addition, a novel synthetic route for the preparation of pyrazino(3,2,1-jk)- and 1,4-diazepino(3,2,1-jk)carbazoles has been realized.
D001381:Azepines / Q000138:chemical synthesis*; D002227:Carbazoles / Q000138:chemical synthesis*; D007211:Indoles / Q000138:chemical synthesis*; D011719:Pyrazines / Q000138:chemical synthesis*; D011758:Pyrroles / Q000138:chemical synthesis*
D001381:Azepines; D002227:Carbazoles; D007211:Indoles; D011719:Pyrazines; D011758:Pyrroles
Pirazino(1,2-a)- e 1,4-diazepino(1,2-a)indoli III - Sintesi di pirrolo(2',1':3,4)pirazino(1,2-a)indoli e pirrolo(2',1':3,4)-1,4-diazepino(1,2-a)indoli; isoindolo(2',1':3,4)pirazino(1,2-a)-indoli e isoindolo(2',1':3,4)-1,4-diazepino(1,2-a)indoli; pirazino(3,2,1-jk)-carbazoli e 1,4-diazepino(3,2,1-jk)carbazoli