Effect of intercostal nerve blockade during operation on lung function and the relief of pain following thoracotomy.
The use, during operation, of intercostal nerve blocks with lignocaine and bupivacaine for the relief of pain following thoracotomy was assessed in 138 patients. Irrespective of the method used to evaluate efficacy, it was not possible to demonstrate a lasting effect of clinical significance favouring either local anaesthetic agent. This form of treatment, although free from serious side effects, had no beneficial effects on lung function and is not recommended for the relief of pain following surgery.
D001794:Blood Pressure; D002045:Bupivacaine / Q000009:adverse effects / Q000494:pharmacology*; D006261:Headache / Q000139:chemically induced; D006801:Humans; D007367:Intercostal Nerves / Q000187:drug effects*; D008012:Lidocaine / Q000009:adverse effects / Q000494:pharmacology*; D009407:Nerve Block; D010149:Postoperative Pain / Q000628:therapy*; D010366:Peak Expiratory Flow Rate; D011674:Pulse; D012119:Respiration / Q000187:drug effects*; D013900:Thoracic Nerves / Q000187:drug effects*; D013903:Thoracic Surgery; D013909:Thorax / Q000601:surgery*; D014797:Vital Capacity; D014839:Vomiting / Q000139:chemically induced
D008012:Lidocaine; D002045:Bupivacaine