Influence of dietary fat upon rats during gestation and lactation.
A comparison was made between rats fed purified rations containing different fats during gestation and lactation and rats fed a commercial ration during similar periods. The purified ration containign 20% cocoa butter did not result in appreciable differences in the mothers (body weight, behavior, litter production, and brain chemistry) or in the 1-day-old neonates (brain chemistry). The purified ration containing 20% safflower oil resulted in fewer completed gestation, in poorer maternal behavior during lactation, and in neonates with small brains. A fat-free purified ration resulted in low brain concentrations of RNA and low RNA-DNA ratios in the mothers.
D000818:Animals; D000831:Animals, Newborn; D001835:Body Weight; D001923:Brain Chemistry; D002099:Cacao; D002784:Cholesterol / Q000032:analysis; D004247:DNA / Q000032:analysis; D004041:Dietary Fats / Q000378:metabolism*; D005260:Female; D007774:Lactation; D008041:Linoleic Acids / Q000378:metabolism; D008055:Lipids / Q000032:analysis; D008297:Male; D008425:Maternal Behavior; D009829:Oleic Acids / Q000378:metabolism; D010169:Palmitic Acids / Q000378:metabolism; D011247:Pregnancy; D011270:Pregnancy, Animal; D012313:RNA / Q000032:analysis; D051381:Rats / Q000378:metabolism* / Q000502:physiology; D012450:Safflower Oil / Q000378:metabolism; D013229:Stearic Acids / Q000378:metabolism
D004041:Dietary Fats; D008041:Linoleic Acids; D008055:Lipids; D009829:Oleic Acids; D010169:Palmitic Acids; D013229:Stearic Acids; D012313:RNA; D012450:Safflower Oil; D004247:DNA; D002784:Cholesterol