Genetic linkage between the HL-A system and a deficit of the second component (C2) of complement.
From a family of 14 individuals, evidence was obtained suggesting linkage between the HL-A haplotypes and the transmission of a 50 percent deficit in the functional activity of the C2 component of complement.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000483:Alleles; D003175:Complement C2 / Q000172:deficiency*; D003165:Complement System Proteins / Q000172:deficiency*; D005260:Female; D008040:Genetic Linkage; D006680:HLA Antigens; D006579:Heterozygote; D006649:Histocompatibility Antigens; D006720:Homozygote; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree
D003175:Complement C2; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D003165:Complement System Proteins