Distribution of sibship size in families manifesting a genetically determined disorder.
The effect on sibship size distribution of the birth of a child with a genetical defect is considered for several different conditions. Family size continues to be over-dispersed in such cases, rather than showing any sign of reduced variation, though theoretical expectations about the correlation between numbers of normal and affected children are not well-supported by the data.
D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D005190:Family; D005260:Female; D014644:Genetic Variation; D006801:Humans; D008297:Male; D011336:Probability