New observations on the epidemiology and pathogenesis of sporotrichosis.
Five uncommon cases of skin sporotrichosis are presented, including a small family outbreak with interesting epidemiological findings and two patients treated with corticosteroids; we attributed the severity of the lesions to the steroids. Mice were used to confirm our hypothesis on the pathogenesis. The pathological findings in case of sporotrichosis in a dog are presented. A group of 359 pulmonary patients was tested with two different antigens of Sporotrichum schenkii.
D000328:Adult; D000818:Animals; D000946:Antigens, Fungal; D002675:Child, Preschool; D003046:Coccidioidin; D004283:Dog Diseases; D004285:Dogs; D005260:Female; D006659:Histoplasmin; D006801:Humans; D006968:Hypersensitivity, Delayed; D007223:Infant; D008297:Male; D051379:Mice; D010944:Plants / Q000382:microbiology; D011134:Polysaccharides / Q000276:immunology; D011239:Prednisolone / Q000009:adverse effects / Q000627:therapeutic use; D012882:Skin Tests; D013175:Sporothrix / Q000302:isolation & purification; D013174:Sporotrichosis / Q000453:epidemiology / Q000235:genetics; D014373:Tuberculin; D014396:Tuberculosis, Pleural / Q000188:drug therapy
D000946:Antigens, Fungal; D011134:Polysaccharides; D014373:Tuberculin; D003046:Coccidioidin; D006659:Histoplasmin; D011239:Prednisolone