Differential uptake and metabolism of sitosterol and cholesterol by Achlya, Pythium, and Phytophthora species.
The relative ability of isolates of Achlya bisexualis and A. ambisexualis and isolates of Pythium and Phytophthora to take up and metabolize sitosterol and cholesterol was studied. Species of Pythium and Phytophthora took up cholesterol and sitosterol efficiently, whereas Achlya species took up booth sterols inefficiently. Species of Pythium and Phytophthora produced a polar metabolite and esters from sitosterol as they did from cholesterol. Achlya species did not produce the polar metabolite from either sterol. In these experiments Achlya species produced esters only from cholesterol; however, their failure to produce esters from sitosterol may have been due to the higher sitosterol than cholesterol concentration.
D002784:Cholesterol / Q000378:metabolism*; D004952:Esters / Q000096:biosynthesis; D005658:Fungi / Q000378:metabolism*; D010838:Phytophthora / Q000378:metabolism; D011775:Pythium / Q000378:metabolism; D012855:Sitosterols / Q000378:metabolism*
D004952:Esters; D012855:Sitosterols; D002784:Cholesterol