Production of trichothecene mycotoxins by Fusarium species in shake culture.
Twelve T-2 toxin-producing isolates and four fusarenon-X-producing isolates of Fusarium species were examined for their ability to produce trichothecene mycotoxins in shake culture and jar fermentation. T-2 toxin producers such as Fusarium solani, F. sporotrichiodes, and F. tricinctum produced T-2 toxin and neosolaniol in semisynthetic medium. F. solani M-1-1 produced the largest amount of the mycotoxins in a nutrient medium consisting of 5% glucose (or sucrose), 0.1% peptone, and 0.1% yeast extract in either shake culture or jar fermentation at 24 to 27 C for 5 days. None of the isolates produced significant amount of fusarenon-X in shake cultures.
D050260:Carbohydrate Metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D003470:Culture Media; D005285:Fermentation; D005670:Fusarium / Q000254:growth & development / Q000378:metabolism*; D008670:Metals / Q000494:pharmacology; D010461:Peptones / Q000378:metabolism; D012717:Sesquiterpenes / Q000096:biosynthesis*; D013997:Time Factors; D014255:Trichothecenes / Q000096:biosynthesis*
D003470:Culture Media; D008670:Metals; D010461:Peptones; D012717:Sesquiterpenes; D014255:Trichothecenes