Management of ischemic complications after subarachnoid hemorrhage.
The author reviews a form of management for patients deteriorating preoperatively or postoperatively from apparent ischemia attributed to progressive vasospasm after a subarachnoid hemorrhage. The clinical picture and relative frequency of this complication are considered in relationship to the status (grade) of the patient, location of the aneurysm, and ultimate neurological recovery. Experience suggests that the drug regimen reported is useful when instituted early after the onset of symptoms and is safe with proper monitoring techniques. The data do not justify early operative intervention after a subarachnoid hemorrhage, operation when there is angiographic evidence of severe spasm, or expectation of a dramatic effect in patients with a profound deficit or a fixed deficit several hours old.
D000328:Adult; D000368:Aged; D001921:Brain / Q000098:blood supply; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000601:surgery; D007511:Ischemia / Q000188:drug therapy* / Q000209:etiology; D002546:Ischemic Attack, Transient / Q000188:drug therapy; D007545:Isoproterenol / Q000627:therapeutic use; D008012:Lidocaine / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy; D013345:Subarachnoid Hemorrhage / Q000150:complications*
D008012:Lidocaine; D007545:Isoproterenol