Six cases of hyperosmolar non-ketotic diabetic decompensation in a hospital practice in West Africa.
During 1972, of 18 patients admitted to St. Luke's Hospital Anua, Uyo, in S.E. Nigeria, with diabetic metabolic decompensation, six were suffering from hyperglycaemic hyperosmolar non-ketotic coma or pre-coma. The clinical features and treatment of these patients are described. All survived. It is suggested that even when biochemical monitoring is unavailable, the overall mortality could be improved by clinical awareness of this commonly unrecognised condition, combined with replacement therapy using half strength normal saline and modest quantities of insulin and potassium.
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D003124:Colorimetry; D003681:Dehydration / Q000628:therapy; D003920:Diabetes Mellitus / Q000175:diagnosis* / Q000178:diet therapy / Q000188:drug therapy; D003926:Diabetic Coma / Q000188:drug therapy*; D005260:Female; D006029:Glycosuria; D006801:Humans; D007263:Infusions, Parenteral; D007275:Injections, Intravenous; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use; D007659:Ketones / Q000652:urine; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D009994:Osmolar Concentration; D012965:Sodium Chloride / Q000008:administration & dosage / Q000627:therapeutic use
D001786:Blood Glucose; D007328:Insulin; D007659:Ketones; D012965:Sodium Chloride