The effect of heat on rat pineal hydroxyindole-omichron-methyl transferase activity.
Exposure of adult male rats to continuously elevated temperature of 32-34 degrees C caused a significant decrease of HIOMT activity involved in the specific metabolic process of production of melatonin, considered an active pineal hormone. The effect was already evident after 24 h exposure and increased further during the next 48 h. The results obtained substantiate previous data that the pineal gland may be involved in the system regulating adaptation to extreme temperature changes.
D000121:Acetylserotonin O-Methyltransferase / Q000378:metabolism*; D000818:Animals; D006358:Hot Temperature; D008297:Male; D008550:Melatonin / Q000378:metabolism; D008780:Methyltransferases / Q000378:metabolism*; D010870:Pineal Gland / Q000201:enzymology*; D051381:Rats; D013997:Time Factors
D008780:Methyltransferases; D000121:Acetylserotonin O-Methyltransferase; D008550:Melatonin