Sinus node function and conduction system after complete repair of tetralogy of Fallot.
Twenty-three children underwent electrophysiological studies during routine postoperative catheterization two months to five years after complete correction of tetralogy of Fallot. The aim of the study was to investigate the whole conduction system, including sinus node function, suing His bundle recordings and atrial pacing. H-V intervals were normal at rest and with pacing in twenty-two patients, including four patients with evidence of bifascicular block on the surface ECG. One patient with cardiomegaly and evidence of diffuse myocardial damage had a prolonged H-V interval but did not develop a block at this level during pacing A-H interval was slightly prolonged in four patients and normal in all others. The threshold of pacing-induced atrioventricular block ranged from 75 to 240/min and was somewhat age dependent (r = -0.55). Two patients fell below the 95% confidence limit of this regression and are considered abnormal. One returned to normal after intravenous injectionof atropine. Corrected sinus node recovery time ranged from 60 to 2000 msec. Three patients had values above 500 msec which are considered abnormal. These patients had other minor signs of sinus node dysfunction, i.e., episodes of sino-atrial block at rest or intermittent sinus bradycardia. Thus, while the His Purkinje system performed satisfactorily in all patients, sinus node dysfunctional and A-V node dysfunction were demonstrated in a few patients after correction of tetralogy of Fallot.
D000293:Adolescent; D000328:Adult; D001146:Arrhythmia, Sinus / Q000209:etiology; D001283:Atrioventricular Node / Q000503:physiopathology; D001285:Atropine / Q000627:therapeutic use; D001919:Bradycardia / Q000209:etiology; D002037:Bundle-Branch Block / Q000209:etiology; D006328:Cardiac Catheterization; D002648:Child; D002675:Child, Preschool; D004562:Electrocardiography; D004594:Electrophysiology; D005260:Female; D005500:Follow-Up Studies; D006327:Heart Block / Q000188:drug therapy / Q000209:etiology; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008297:Male; D010138:Pacemaker, Artificial; D011183:Postoperative Complications / Q000175:diagnosis; D012848:Sinoatrial Block / Q000209:etiology; D012849:Sinoatrial Node / Q000503:physiopathology; D013771:Tetralogy of Fallot / Q000503:physiopathology / Q000601:surgery*
D001285:Atropine