Interactive simulator for pharmacokinetics of repetitive drug dosing.
DRUGSIM is a highly interactive program allowing simulation of the effects of repeated drug administration by a variety of routes on plasma concentrations of drugs over a period of time. Drug parameters are read from a data file; prescriptions are obtained from the user at various points during run time. The results for one or two compartment pharmacokinetics are plotted on a storage display tube, and the user is queried for further prescriptions. Simulation involves a point-slope method with a variable time step. The program is written in Fortran IV and run on a DEC PDP-10 computer using a Computek 611 display terminal.
D000284:Administration, Oral; D003201:Computers; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007263:Infusions, Parenteral; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D007700:Kinetics; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000008:administration & dosage* / Q000097:blood; D010600:Pharmacology
D004364:Pharmaceutical Preparations