Induction of mutation to streptomycin resistance in Micrococcus radiodurans.
No detectable induction of mutation to streptomycin resistance could be used in wild-type Micrococcus radiodurans and its radiation-sensitive and super-resistant mutants by ionizing or UV-radiation. N-methyl-N'-nito-N-nitrosoguanidine (NTG) was mutagenically active. The results suggest that repair of radiation-damaged DNA in Micrococcus radiodurans is mutation-proof.
D003037:Cobalt Radioisotopes; D004260:DNA Repair; D004269:DNA, Bacterial / Q000528:radiation effects; D004352:Drug Resistance, Microbial; D008837:Micrococcus / Q000187:drug effects*; D009153:Mutagens / Q000494:pharmacology; D009154:Mutation; D009604:Nitrosoguanidines / Q000494:pharmacology; D011831:Radiation Genetics; D013307:Streptomycin / Q000494:pharmacology*; D014466:Ultraviolet Rays
D003037:Cobalt Radioisotopes; D004269:DNA, Bacterial; D009153:Mutagens; D009604:Nitrosoguanidines; D013307:Streptomycin