Effects of gastric loads and food deprivation on subsequent food intake in suckling rats.
Suckling rats were subjected to deprivation periods of 6-8 hr. Intake following deprivation was greater in deprived than in nondeprived sucklings, but did not increase with increasing deprivation. Gastric loads of NaCl solutions depressed subsequent intake; 3% NaCl was more effective than .9% NaCl. Other gastric loads of varying osmotic and caloric value also depressed subsequent intake. In order of increasing effectiveness in depressing intake, the gastric loads were protein hydrolystate, heavy cream, water, milk, lactose, glucose, and corn oil. Effectiveness was unrelated to osmotic or caloric value of the load. Gastric fill and, possibly, some property of carbohydrate appear to be important determinants of satiety in the suckling rat.
D000367:Age Factors; D000596:Amino Acids / Q000494:pharmacology; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D001835:Body Weight; D003611:Dairy Products; D004041:Dietary Fats / Q000494:pharmacology; D005247:Feeding Behavior; D005508:Food Deprivation; D005947:Glucose / Q000494:pharmacology; D007441:Intubation, Gastrointestinal; D007785:Lactose / Q000494:pharmacology; D008892:Milk; D009994:Osmolar Concentration; D051381:Rats; D012527:Satiation; D012965:Sodium Chloride / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology; D013997:Time Factors
D000596:Amino Acids; D004041:Dietary Fats; D012965:Sodium Chloride; D005947:Glucose; D007785:Lactose