[1-(2-Diethylaminoethyl)-3,4-pentamethylenepyrazole and N2-substituted bornylenepyrazoles].
An unambiguous synthesis of 1-(2-diethylaminoethyl)-3,4-pentamethylenepyrazole (III) by acid cyclization of 2-(2-cycloheptanonyl)-1,3-dioxolane 2-diethylaminoethylhydrazone, and of N2-methyl and N2-(2-diethylaminoethyl)bornylenepyrazole (VIII) and (IX), by heating the hydrazones from 3-hydroxymethylene-2-bornanone and methylhydrazine or 2-diethylaminoethylhydrazine respectively, is described. (III) showed antiinflammatory activity and (VIII) an anticonvulsant action.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000494:pharmacology; D001892:Camphanes / Q000138:chemical synthesis* / Q000494:pharmacology; D004565:Electroconvulsive Therapy; D007249:Inflammation / Q000188:drug therapy; D051379:Mice; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000893:Anti-Inflammatory Agents; D000927:Anticonvulsants; D001892:Camphanes; D011720:Pyrazoles
1-2(Dietilaminoetil)-3,4-pentametilenpirazolo e bornilenpirazoli N2-sostituiti