Monoamine oxidase activity of the hypothalamus and pituitary: alterations after pinealectomy, changes in photoperiod, or additions of melatonin in vitro.
Rat pituitary MAO activity was reduced by constant darkness and by additions of melatonin in vitro and was increased by constant light and by pinealectomy. Hypothalamic MAO activity followed the same pattern but was less dramatically affected. The data suggest that MAO may be a target enzyme for melatonin.
D000818:Animals; D007031:Hypothalamus / Q000201:enzymology*; D008027:Light; D008550:Melatonin / Q000494:pharmacology; D008995:Monoamine Oxidase / Q000378:metabolism*; D008996:Monoamine Oxidase Inhibitors; D010870:Pineal Gland / Q000502:physiology; D010902:Pituitary Gland / Q000201:enzymology*; D051381:Rats
D008996:Monoamine Oxidase Inhibitors; D008995:Monoamine Oxidase; D008550:Melatonin