Comparative determination of total serum thyroxine. Radio-immunoassay and protein-binding assay.
The precision, accuracy, sensitivity and clinical results of a radio-immunological method for the determination of total serum thyroxine are compared with similar criteria of a competitive protein-binding assay. Application of both methods in the assay of thyroxine in 150 serum samples gave good agreement between the two techniques. The radio-immunoassay offers certain methodological advantages and is considerably less costly than thyroxine determinations in which commercially available kits are used.
D003365:Costs and Cost Analysis; D004967:Estrogens / Q000494:pharmacology; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood; D007037:Hypothyroidism / Q000097:blood; D007457:Iodine Radioisotopes; D011863:Radioimmunoassay; D011869:Radioligand Assay; D013974:Thyroxine / Q000097:blood*
D004967:Estrogens; D007457:Iodine Radioisotopes; D013974:Thyroxine