The observation of myofibroblasts in hypertrophic scars.
Contractile fibroblasts, myofibroblasts, are common cellular components of immature human hypertrophic scars. The contraction of these cells, could play a significant role in the elevation of the scar tissue. The appearance of such cells within granulation tissue suggests that the tissue is pre-disposed to hypertrophy at an early stage of repair.
D001706:Biopsy; D002921:Cicatrix / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D005347:Fibroblasts / Q000648:ultrastructure*; D006801:Humans; D006984:Hypertrophy; D009210:Myofibrils / Q000648:ultrastructure*