[Multiplication of sindbis virus in Drosophila cells cultivated in vitro (author's transl)].
Sindbis virus replicates in Drosophila cell cultures without any cytopathic effect. In continuous cell lines the virus is able to establish a persistent infection similar to other arboviruses in insect cell lines. The growth curve of Sindbis virus in Drosophila cells shows a maximum virus yield at around 24 hours postinfection, thereafter the virus production decreases and then remains fairly constant during a number of cell divisions. The average virus yield per cell has been estimated to be small, i.e. at best 5 PFU per day.
D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured; D004330:Drosophila / Q000382:microbiology*; D012845:Sindbis Virus / Q000254:growth & development*; D014779:Virus Replication
Multiplication du virus sindbis dans des cellules de Drosophile cultivées in vitro