[Influence of the bone-cement mixing time on hypotonic blood circulation reactions in hip-joint replacement surgery].
The amount of methylmethacrylatemonomer that is released into the blood-stream, during the alloplastic replacement of the hip-joint, depends on the time taken to prepare the bone cement(so-called extracorporeal polymerization-time). In vitro experiments reveal that the release of monomers depends on the preparation time. Gas-chromatographic monomer determinations show, that by prolongation of the preparation time from 2 to 5 minutes, the amount of monomer released into the blood-stream is decreased by a factor of 7. With the increase in preparation time the number of hypotonic circulatory reactions caused by the monomers will decrease. Extension of the extracorporeal polymerization-time from 2 to 5 minutes decreases the incidence of intra-operative circulatory depressions from 95% to 26%. These results were obtained by intra-arterial measurements of the blood pressure in the radial artery.
D001775:Blood Circulation / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D001843:Bone Cements; D002306:Cardiac Volume / Q000187:drug effects; D002849:Chromatography, Gas; D006621:Hip Joint / Q000601:surgery*; D006801:Humans; D007595:Joint Prosthesis; D008768:Methylmethacrylates / Q000494:pharmacology; D013997:Time Factors
D001843:Bone Cements; D008768:Methylmethacrylates
Der Einflubeta der Anrührzeit des Knochenzements auf hypotone Kreislaufreaktionen bei Hüftgelenksersatzoperationen