The effect of calcium on plasma lipids and bile acid and fecal fat excretion in normolipidemic subjects.
The effect of oral calcium (2 g/day) was studied in four normolipidemic subjects. Calcium caused a significant lowering of plasma cholesterol and a considerable fall in the glycine-/taurine-conjugated bile acid ratio in the intestinal aspirate of one subject, while fecal bile acid excretion rose appreciably in another during treatment. These parameters showed no consistent trend in the other three subjects. None of the subjects showed any significant change in plasma triglycerides and serum calcium and phosphorus during treatment. One subject showed a consistent decrease in every parameter studied throughout the experiment, a trend which was probably due to a concomitant loss in body weight.
D000328:Adult; D001647:Bile Acids and Salts / Q000378:metabolism*; D001835:Body Weight; D002118:Calcium / Q000097:blood / Q000494:pharmacology*; D002784:Cholesterol / Q000097:blood; D004032:Diet; D005243:Feces / Q000032:analysis; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism; D050356:Lipid Metabolism; D008074:Lipoproteins / Q000097:blood; D010710:Phosphates / Q000097:blood; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
D001647:Bile Acids and Salts; D008074:Lipoproteins; D010710:Phosphates; D014280:Triglycerides; D002784:Cholesterol; D002118:Calcium