[The serum concentration of vitamin A in patients with psoriasis vulgaris after oral administration of vitamin A palmitate].
After oral application of vitamin-A-palmitate in male patients with psoriasis we hourly estimated the serum concentration of vitamin A. With rapidly elevating the maximum vitamin A level was achieved in 3-4 hrs but redescended to the initial level within 24 hrs by an exponential decrease. The curve could be fitted to the "BATEMANfunction". The velocity contents k1 and k2 were calculated but were varied individually. The constant b, the time between oral application and the commencement of resorption, was estimated at 30-60 min. The chromatographical analysis of the total vitamin A in all patients yielded a unique ratio of vitamin A-alcohol, -acetate and -palmitate for each hour.
D000085:Acetates / Q000097:blood; D000284:Administration, Oral; D000328:Adult; D006801:Humans; D008297:Male; D008875:Middle Aged; D010169:Palmitic Acids / Q000378:metabolism; D011565:Psoriasis / Q000097:blood*; D013997:Time Factors; D014801:Vitamin A / Q000008:administration & dosage / Q000097:blood*
D000085:Acetates; D010169:Palmitic Acids; D014801:Vitamin A
Das Verhalten des Serum-Vitamin-A-Spiegels bei Patienten mit Psoriasis vulgaris nach oraler Belastung mit Vitamin-A-palmitat