Proceedings: Acute and chronic effects of the aldosterone antagonist spironolactone and its main metabolite canrenone on plasma aldosterone concentration, plasma renin activity, serum electrolytes and on the excretion of aldosterone, fluid and electrolytes in rats.
D000450:Aldosterone / Q000097:blood* / Q000378:metabolism; D000818:Animals; D002192:Canrenone / Q000494:pharmacology*; D004573:Electrolytes / Q000097:blood* / Q000378:metabolism; D008297:Male; D011245:Pregnadienes / Q000494:pharmacology*; D051381:Rats; D012083:Renin / Q000097:blood*; D013148:Spironolactone / Q000494:pharmacology*
D004573:Electrolytes; D011245:Pregnadienes; D013148:Spironolactone; D000450:Aldosterone; D002192:Canrenone; D012083:Renin