Marijuana-produced changes in pain tolerance. Experienced and non-experienced subjects.
The effect of marijuana and placebo on pain tolerance was compared in cannabis-experienced and naive subjects. A statistically significant increase in tolerance was observed after smoking marijuana. Although there was no statistically significant interaction between the drug effect and having had previous cannabis experience, there was a definite trend towards a greater increase for the experienced (16%) compared to the naive group(8%).
D000328:Adult; D000704:Analysis of Variance; D002188:Cannabis / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D010146:Pain / Q000503:physiopathology*; D010919:Placebos; D011312:Pressure; D011930:Reaction Time / Q000187:drug effects; D012737:Sex Factors
D010919:Placebos