Elevated left ventricular stiffness by noradrenaline in myocardial ischaemia.
Infusion of noradrenaline (1.0 mug/kg/min body weight, i.v.) brings about an increase of the diastolic wall stiffness in the ischaemic canine heart. Similar effect is not elicitable in the normal heart.
D000818:Animals; D001158:Arteries; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D003327:Coronary Disease / Q000503:physiopathology*; D004285:Dogs; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006352:Heart Ventricles / Q000503:physiopathology*; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology*
D009638:Norepinephrine