[Radiation-induced changes of skin enzyme activity. II. Acid phosphatase, alkaline phosphatase].
After application of solf X-rays with 100, 500 and 1000 R, the activity change of the acid and alcaline phosphatase in the skin of mice has been studied. The studies happened immediatly after the irradiation and at the 1st, 2nd, 4th, 8th and 16th day. The measurment of the enzyme activity washable out of the skin and remianing in the skin after the washing and the total activity of the skin have been taken up. With the acid phosphatase it would be determined that the quantity washable out of the skin is unusually low; the acitity values of the wash solution increase at the 2nd day after the irradiation in dependence on the applicated dose;at the moment 0 after an irradiation with 1000 R, a significative activity increase in the wash solution appears; the homogenate activity at the 2nd day only gets a significative activity increase after the irradiation with 500 R. The alcaline phosphatase was measurable in the wash solution at no moment of the measurement. However, the alcaline phosphatase has been decreased in the homogenate with few exceptions.
D000135:Acid Phosphatase / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D004307:Dose-Response Relationship, Radiation; D008247:Lysosomes / Q000201:enzymology; D008297:Male; D051379:Mice; D011830:Radiation Effects; D012867:Skin / Q000201:enzymology / Q000528:radiation effects*; D012996:Solutions; D013997:Time Factors
D012996:Solutions; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase
Untersuchungen über Enzymaktivitätsveränderungen der Haut, verursacht durch Böntgenstrahlen. II. Acidphospatase, alkalische Phospatase