Altered growth of hormone secretory pattern following prolonged sleep deprivation in the rhesus monkey.
Plasma concentrations of growth hormone (GH) were determined in samples obtained sequentially at 15-min intervals during the last 4 h in monkeys deprived of sleep for 76 h and the first 8 h of ensuing recovery sleep. Electroencephalographic (EEG), electro-oculographic (EOG), and electromyographic (EMG) activities were recorded. Stages 3-4 sleep occurred rapidly after sleep onset and were of long duration. Plasma GH secretion was markedly elevated during sleep recovery, without apparent relationship to stage of sleep.
D000818:Animals; D002940:Circadian Rhythm; D004569:Electroencephalography; D004576:Electromyography; D004585:Electrooculography; D013006:Growth Hormone / Q000097:blood*; D008251:Macaca / Q000502:physiology*; D008253:Macaca mulatta / Q000502:physiology*; D008297:Male; D012890:Sleep; D012892:Sleep Deprivation; D013997:Time Factors; D014851:Wakefulness
D013006:Growth Hormone