Coagulation-time determination with automatic multivariable analysis, by use of a miniature centrifugal fast analyzer.
Use of a miniature Centrifugal Fast Analyzer for the parallel photometric monitoring of the coagulation process is shown to have a number of advantages. These include a choice of optical modes, virtually simultaneous initiation and observation of the coagulation process for a number of patient-plasma samples and an on-board control sample, small sample and reagent volume requirements, and automatic determination of a number of diagnostically useful variables (including relative fibrinogen content) from the data recorded in a single run. Also, the system is shown to give results that correlate well with those obtained by conventional techniques for determination of prothrombin time.
D001322:Autoanalysis; D001780:Blood Coagulation Tests / Q000379:methods*; D002498:Centrifugation; D003202:Computers, Analog; D005069:Evaluation Studies as Topic; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D008433:Mathematics; D011517:Prothrombin Time; D012044:Regression Analysis; D013997:Time Factors
D005340:Fibrinogen