Some effects of the behaviorally active drug, phenitrone, a purported hashish and LSD antagonist, on brain noradrenergic and serotonergic systems.
Phenitrone, (3-hexahydro-1H-azepin-yl)-3'-nitropriophenone HCl) had no effect on brain norepinephrine levels but decreased serotonin levels and serotonin turnover rate.
D000818:Animals; D001381:Azepines / Q000494:pharmacology*; D001923:Brain Chemistry / Q000187:drug effects; D002188:Cannabis / Q000037:antagonists & inhibitors*; D004347:Drug Interactions; D007700:Kinetics; D008238:Lysergic Acid Diethylamide / Q000037:antagonists & inhibitors*; D051379:Mice; D009638:Norepinephrine / Q000378:metabolism / Q000502:physiology*; D010293:Pargyline / Q000494:pharmacology; D011427:Propiophenones / Q000494:pharmacology*; D012701:Serotonin / Q000378:metabolism / Q000502:physiology*; D013997:Time Factors
D001381:Azepines; D011427:Propiophenones; D012701:Serotonin; D008238:Lysergic Acid Diethylamide; D010293:Pargyline; D009638:Norepinephrine