Nature of anionic or alpha-site of cholinesterase.
The nature of the so-called anionic binding site of acetylcholinesterase was investigated using a technique called receptor mapping using model interaction calculations. The results support the suggestion that coulombic forces play only a minor role in the binding event at this enzyme site.
D000109:Acetylcholine / Q000031:analogs & derivatives; D001665:Binding Sites; D002802:Cholinesterases / Q000032:analysis*; D006868:Hydrolysis; D007700:Kinetics; D008956:Models, Chemical; D008968:Molecular Conformation; D013816:Thermodynamics
D002802:Cholinesterases; D000109:Acetylcholine