A new method simplifying collection of serial specimens for gonadotropin determinations.
Patterns of gonadotropin levels have been compared in specimens of serum, 24-h urine collections, and first morning urine voidings collected throughout a menstrual cycle from 8 sexually mature, young women. Quantities of gonadotropins in first morning voidings were found to provide a reliable estimate of 24-h excretion of these hormones and demonstrate the same patterns of change as do serum and 24-h urine specimens. Thus first morning voidings satisfactorily overcome logistical problems inherent is serial serum and 24-h urine sampling for studying gonadotropin excretion patterns.
D000293:Adolescent; D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood; D002940:Circadian Rhythm; D003404:Creatinine / Q000097:blood; D003429:Cross Reactions; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006062:Gonadotropins / Q000032:analysis* / Q000097:blood / Q000652:urine; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D013048:Specimen Handling / Q000379:methods*; D013997:Time Factors
D006063:Chorionic Gonadotropin; D006062:Gonadotropins; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D003404:Creatinine