Influence of vitamin E on platelet aggregation and thrombocythemia in the rat.
Collagen-induced platelet aggregation was increased in 9-10 wk old vitamin E deficient rats although there was no difference in platelet count between deficient and control animals. With a more prolonged deficiency (at 15 wk) both platelet aggregation and platelet counts were elevated in the vitamin E deficient animals.
D000367:Age Factors; D000818:Animals; D001772:Blood Cell Count; D001792:Blood Platelets; D003094:Collagen / Q000494:pharmacology; D008297:Male; D010973:Platelet Adhesiveness / Q000187:drug effects*; D010974:Platelet Aggregation / Q000187:drug effects*; D051381:Rats; D013922:Thrombocytosis / Q000097:blood; D014810:Vitamin E / Q000494:pharmacology*; D014811:Vitamin E Deficiency / Q000097:blood
D014810:Vitamin E; D003094:Collagen