Effect of thyroid hormones on activity of nonspecific phosphohydrolases in blood serum, tissues and liver mitochondrial fraction of white rat.
Activity of alkaline and acid phosphatase was determined by the method of Bodansky in blood serum, homogenates of liver, kidney, lung, brain, liver mitochondrial fraction of normal, methylthiouracil-induced hypothyroid, and Thyroideum-induced hyperthyroid rats. The following results were obtained: an increase in both enzymes in all studied materials in hyperthyroidism, and a decrease in most of the studied materials in hypothyroidism.
D000135:Acid Phosphatase / Q000097:blood / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000201:enzymology; D006980:Hyperthyroidism / Q000139:chemically induced / Q000201:enzymology*; D007037:Hypothyroidism / Q000139:chemically induced / Q000201:enzymology*; D008168:Lung / Q000201:enzymology; D008297:Male; D008779:Methylthiouracil / Q000009:adverse effects; D008930:Mitochondria, Liver / Q000201:enzymology*; D051381:Rats; D013963:Thyroid Hormones / Q000502:physiology*
D013963:Thyroid Hormones; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D008779:Methylthiouracil