Hypothermic action of bromocriptine.
The body temperature of rats has been studied in a cold environment. In this setting, bromocriptine induced hypothermia. This fall in core temperature was inhibited by pimozide. It was concluded that bromocriptine has a dopamine-like action in areas of the brain concerned with the control of body temperature, as has previously been shown for apomorphine and amphetamine.
D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D001058:Apomorphine / Q000494:pharmacology; D001833:Body Temperature Regulation / Q000187:drug effects*; D001921:Brain / Q000187:drug effects*; D001971:Bromocriptine / Q000494:pharmacology*; D003080:Cold Temperature; D003106:Colon; D018492:Dopamine Antagonists; D004305:Dose-Response Relationship, Drug; D004780:Environment, Controlled; D004873:Ergolines / Q000494:pharmacology*; D007035:Hypothermia / Q000139:chemically induced; D008297:Male; D010868:Pimozide / Q000494:pharmacology; D051381:Rats
D018492:Dopamine Antagonists; D004873:Ergolines; D010868:Pimozide; D001971:Bromocriptine; D000661:Amphetamine; D001058:Apomorphine