Assay of brinase inhibitors with soluble and insoluble substrates.
Two methods for the assay of brinase inhibitors are compared. Neither provided a reliable means of brinase dose prediction. Overdosage can, however, be avoided by preinfusion inhibitor assay.
D001230:Aspergillus / Q000201:enzymology; D004791:Enzyme Inhibitors / Q000032:analysis; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006801:Humans; D010447:Peptide Hydrolases / Q000008:administration & dosage; D011480:Protease Inhibitors; D012995:Solubility
D004791:Enzyme Inhibitors; D005343:Fibrinolytic Agents; D011480:Protease Inhibitors; D010447:Peptide Hydrolases