Mid-trimester abortion with intra-amniotic prostaglandin F2 alpha and intravenous oxytocin infusion.
Induction of abortion in mid-trimester pregnancies were performed on 26 patients. The first 12 patients were treated by intra-amniotic instillation of Prostaglandin F2 alpha, with a mean dosage of 40.2 mg. and mean abortion time of 24 hours and 41 minutes (ten patients). Fourteen additional mid-trimester abortions were performed using identical protocol plus the addition of oxytocin by intravenous infusion two hours after injection of the prostaglandin. All patients aborted, with mean dosage of PGF2 alpha of 28.2 mg. and mean abortion time of 15 hours and 37 minutes.
D000028:Abortion, Induced; D000293:Adolescent; D000328:Adult; D000650:Amnion; D005260:Female; D006801:Humans; D007267:Injections; D007275:Injections, Intravenous; D010121:Oxytocin / Q000008:administration & dosage / Q000627:therapeutic use*; D010298:Parity; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011460:Prostaglandins F / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D014590:Uterine Contraction
D011460:Prostaglandins F; D010121:Oxytocin