Evaluation of University of Florida split-course technique for various head and neck squamous cell carcinomas.
A retrospective evaluation was made of 260 patients with squamous carcinoma of various head and neck sites in order to determine the relative value of continuous vs. split-course irradiation techniques.  There was no obvious difference in local control or survival in early-stage cases.  The continuous technique resulted in a better local control and survival rate in moderately advanced and advanced stages.  Complications were less severe in the split-course cases.
D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D004825:Epiglottis; D006258:Head and Neck Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D009062:Mouth Neoplasms / Q000401:mortality / Q000532:radiotherapy; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy; D010610:Pharyngeal Neoplasms / Q000532:radiotherapy; D011878:Radiotherapy / Q000009:adverse effects / Q000379:methods; D011879:Radiotherapy Dosage; D012189:Retrospective Studies