Morphological features in the peripheral blood film indicating the presence of cryoproteins.
Light gray, irregular threads in a May-Grünwald & Giemsa stained blood film made of EDTA-blood some time after drawing may sometimes call attention to a previously unsuspected cryoproteinaemia. The cryoproteinaemia discovered in this way in our patient consisted of IgG complexes resulting in proteinuria. After treatment with prednisone and cyclophosphamide the cryoproteinaemia and proteinuria disappeared.
D000328:Adult; D001796:Blood Protein Disorders / Q000097:blood* / Q000188:drug therapy; D003450:Cryoglobulins; D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D011507:Proteinuria / Q000188:drug therapy
D003450:Cryoglobulins; D007074:Immunoglobulin G; D003520:Cyclophosphamide; D011241:Prednisone