Retinitis Pigmentosa. A biomicroscopical study of vitreous abnormalities.
A biomicroscopical study of the vitreous body was performed on 116 eyes of 58 patients with primary retinitis pigmentosa, and six additional eyes were examined histopathologically. A characteristic vitreous degeneration, found in all eyes, was clinically divided into four sequential stages that appear to parallel the magnitude of gross retinal destruction as determined by visual-field measurements. The vitreous breakdown in retinitis pigmentosa may be due to progressive loss of hyaluronic acid from the hyaluronic acid-collagen complex.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003094:Collagen / Q000032:analysis; D005128:Eye Diseases / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D006820:Hyaluronic Acid / Q000032:analysis; D008297:Male; D008875:Middle Aged; D012174:Retinitis Pigmentosa / Q000150:complications* / Q000473:pathology; D014822:Vitreous Body / Q000032:analysis / Q000473:pathology
D006820:Hyaluronic Acid; D003094:Collagen