Anonychia with bizarre flexural pigmentation-an autosomal dominal dermatosis.
A nulliparous female aged 26 years, who presented with long-standing sore and cracked soles, showed congenital anonychia, long-standing hyper-and-hypo-pigmentation in axillae and groins, dry palmar and plantar skin as well as other skin and hair abnormalities. She gave a family history of nail, hair and pigmentary abnormalities and examination of living affected relatives confirmed this. This appears to be a hitherto undescribed autosomal dominant syndrome.
D000293:Adolescent; D000328:Adult; D001365:Axilla; D003878:Dermatoglyphics; D005260:Female; D005799:Genes, Dominant; D006197:Hair; D006801:Humans; D008297:Male; D009264:Nails, Malformed; D010375:Pedigree; D010859:Pigmentation Disorders / Q000150:complications / Q000235:genetics*; D013546:Sweating; D014076:Tooth Diseases / Q000150:complications