Anti-inflammation mechanism of extract from Eisenia bicyclis (Kjellman) Setchell.
An extract from Eisenia bicyclis, previously shown to possess anti-inflammatory activity, was found to stabilize lysosomal membranes in vitro as determined by measurement of inhibition of the marker enzyme beta-glucuronidase. Some anti-inflammatory activity was also due to counterirritancy.
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002351:Carrageenan; D056890:Eukaryota; D005966:Glucuronidase / Q000378:metabolism; D066298:In Vitro Techniques; D007249:Inflammation / Q000139:chemically induced; D008099:Liver / Q000648:ultrastructure; D008247:Lysosomes / Q000187:drug effects / Q000201:enzymology; D008297:Male; D008566:Membranes / Q000201:enzymology; D010936:Plant Extracts / Q000494:pharmacology; D051381:Rats
D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; D002351:Carrageenan; D000135:Acid Phosphatase; D005966:Glucuronidase