Determination of sorbitol and mannitol in pharmaceuticals by GLC of tris-n-butyldiboronate esters.
A rapid method for determining sorbitol or mannitol in pharmaceuticals by GLC using the tris-n-butyldiboronate esters is described. An internal standard unrelated to the hexitols is utilized to avoid the problems of cross-contamination introduced by the use of other hexitols.
D001888:Boric Acids; D001896:Boron Compounds; D002849:Chromatography, Gas / Q000379:methods; D008353:Mannitol / Q000032:analysis*; D013012:Sorbitol / Q000032:analysis*
D001888:Boric Acids; D001896:Boron Compounds; D008353:Mannitol; D013012:Sorbitol