[Antioxidants as cytochrome stabilizers in endoplasmic reticulum membranes of rat liver in vivo].
It has been shown that synthetic antioxidant 4-methyl-2, 6-ditrebuthylphenole (ionole) inhibits free radical oxidation of phospholipids in the membranes of endoplasmic reticulum, increases the life time of cytochrome P-448 after its induction with 20 methylcholantrene.
D015073:2-Acetylaminofluorene; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002084:Butylated Hydroxytoluene / Q000494:pharmacology*; D003408:Cresols / Q000494:pharmacology*; D003580:Cytochromes / Q000378:metabolism*; D004721:Endoplasmic Reticulum / Q000187:drug effects / Q000201:enzymology*; D004790:Enzyme Induction; D008099:Liver / Q000187:drug effects / Q000201:enzymology* / Q000378:metabolism; D008566:Membranes / Q000187:drug effects / Q000201:enzymology; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000378:metabolism; D010545:Peroxides / Q000378:metabolism; D051381:Rats
D000975:Antioxidants; D003408:Cresols; D003580:Cytochromes; D010545:Peroxides; D002084:Butylated Hydroxytoluene; D008748:Methylcholanthrene; D015073:2-Acetylaminofluorene; D006899:Mixed Function Oxygenases
Antioksidanty kak stabilizatory tsitokhromov v membranakh éndoplazmaticheskogo retikuluma pecheni krys in vivo