Hypothalamo-pituitary-adrenal function following subarachnoid hemorrhage.
The endocrine function was evaluated in 50 patients a minimum of 3.5 months after a subarachnoid hemorrhage. The hypothalamo-pituitary-adrenal function was assessed by studying the circadian rhythm of plasma 11-hydroxycorticosteroids and with the metyrapone test. In addition, screening methods were used to evaluate thyroid and gonadal functions. The results indicate that hypothalamo-pituitary-adrenal disturbances may occur in patients surviving a subarachnoid hemorrhage. In patients who have survived a subarachnoid hemorrhage more than 3.5 months, however, frank hypopituitarism is rare.
D015062:11-Hydroxycorticosteroids / Q000097:blood; D000311:Adrenal Glands / Q000378:metabolism / Q000503:physiopathology*; D000328:Adult; D000368:Aged; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007031:Hypothalamus / Q000378:metabolism / Q000503:physiopathology*; D008297:Male; D008797:Metyrapone; D008875:Middle Aged; D010902:Pituitary Gland / Q000378:metabolism / Q000503:physiopathology*; D013345:Subarachnoid Hemorrhage / Q000097:blood / Q000503:physiopathology*
D015062:11-Hydroxycorticosteroids; D006854:Hydrocortisone; D008797:Metyrapone