A 14/14 marker chromosome lymphocyte clone in ataxia telangiectasia.
A lymphocyte clone with a 45, XY karyotype with a 14/14 tandem translocation marker, the frequency of which is time-variable, has been observed in an ataxia telangiectasia patient. Cells with the marker chromotosome were not observed in fibroblasts cultures derived from a skin biopsy, nor was the marker observed in leukocyte cultures from the patient's two affected sibs.
D001260:Ataxia Telangiectasia / Q000097:blood / Q000235:genetics*; D002648:Child; D002869:Chromosome Aberrations; D002901:Chromosomes, Human, 13-15; D002999:Clone Cells; D003241:Consanguinity; D005260:Female; D005347:Fibroblasts / Q000648:ultrastructure; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D014178:Translocation, Genetic