Brain creatine kinase in blood after acute brain injury.
Severe cold injury of the brain increased significantly both total creatine kinase and the corresponding brain isoenzyme (CKBB) activity in confluens sinuum samples. CKBB could be detected also in peripheral blood a few hours after severe brain injury in eight of 12 patients. Finding of CKBB in human plasma may prove a useful indicator of severe brain injury.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D001924:Brain Concussion / Q000175:diagnosis; D001930:Brain Injuries / Q000097:blood / Q000175:diagnosis*; D004796:Clinical Enzyme Tests; D003288:Contusions / Q000175:diagnosis; D003392:Cranial Sinuses; D003402:Creatine Kinase / Q000097:blood*; D006408:Hematoma, Subdural / Q000175:diagnosis; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D011817:Rabbits; D013997:Time Factors
D007527:Isoenzymes; D003402:Creatine Kinase