A comparative analysis of warfarin and low-dose heparin as thromboembolism prophylaxis in total hip replacement patinets.
Warfarin, low-dose heparin, or a combination of low-dose heparin and hydrocortisone was administered to 300 patients undergoing total hip replacement. The lowest incidence of thromboembolic (5 per cent) was attained with Warfarin. Further investigation into the method of administration of low-dose heparin is necessary before it can be used effectively as thromboembolism prophylaxis in total hip replacement patients. The addition of hydrocortisone was not found useful.
D001178:Arthroplasty; D004359:Drug Therapy, Combination; D006493:Heparin / Q000008:administration & dosage / Q000627:therapeutic use; D006615:Hip / Q000601:surgery*; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage / Q000627:therapeutic use; D010689:Phlebitis / Q000188:drug therapy; D011183:Postoperative Complications; D011655:Pulmonary Embolism / Q000188:drug therapy; D013923:Thromboembolism / Q000517:prevention & control*; D014859:Warfarin / Q000008:administration & dosage / Q000627:therapeutic use*
D014859:Warfarin; D006493:Heparin; D006854:Hydrocortisone