Craniofacial serial dimensions related to age, sex, and cleft-type from six months of age to two years.
The first two postnatal years are a time of rapid craniofacial growth. We selected 30 cleft lip/palate children, each seen at 6, 12, 18, 24 months, at which time lateral X-ray headfilms were taken. There were five boys, five girls, in each of three cleft-types: cleft palate only (CP), unilateral cleft lip/palate (UCLP), and bilateral cleft lip/palate (BCLP). Three dimensions were selected: 1) anterior cranial base (S-N); 2) upper face height (N-Pt.A); 3) maxillary depth (Pt.A-Ptm). All were in the midsagittal plane. This is a repeated measures study on the factor patient age, so that for each combination of sex and cleft-type the same subject was measured at the four levels of patient age. The multiple comparison technique utilized was the Newman-Keuls Procedure. There is no significant joint effect in the 6-24 months period. The factors seem to operate singly. There is no main effect due to the factor sex. Dimensions N-Pt.A. and Pt.A-Ptm show a significant main effect due to the factor cleft-type. There is a highly significant main effect due to the patient age factor.
D000367:Age Factors; D000704:Analysis of Variance; D002508:Cephalometry; D002675:Child, Preschool; D002971:Cleft Lip / Q000196:embryology; D002972:Cleft Palate / Q000196:embryology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008445:Maxillofacial Development; D012737:Sex Factors; D012886:Skull / Q000254:growth & development*