Diabetic vacuolation of the iris pigment epithelium.
In a postmortem study of 57 diabetic patients, 19 of 23 patients with blood glucose levels greater than 200 mg/100 ml in the 72-hour period before death showed the characteristic histologic findings of "lacy" vacuolation of the iris pigment epithelium as well as vacuolation of the renal tubules (Armanni-Ebstein nephropathy). Conversely, 33 of the remaining 34 patients with blood glucose levels below 200 mg/100 ml in the 72-hour period prior to death showed no vacuolation in the iris or kidney.
D001786:Blood Glucose / Q000032:analysis; D048909:Diabetes Complications; D003928:Diabetic Nephropathies / Q000473:pathology; D004848:Epithelium / Q000648:ultrastructure; D006003:Glycogen / Q000378:metabolism; D007498:Iris / Q000648:ultrastructure*; D007684:Kidney Tubules / Q000648:ultrastructure; D013577:Syndrome; D014617:Vacuoles / Q000648:ultrastructure
D001786:Blood Glucose; D006003:Glycogen