Bromide pharmocokinetics: a model for residue accumulation in animals.
Using data obtained from pharmacokinetic experiments with bromide, illustrations are given of the application of pharmacokinetics to toxicological studies. Analog computers may be helpful, though not indispensable. The significance of ancillary pharmacokinetic investigations in the evaluation of toxicity studies is discussed.
D000818:Animals; D001965:Bromides / Q000378:metabolism* / Q000633:toxicity; D003202:Computers, Analog; D003203:Computers, Hybrid; D006207:Half-Life; D007700:Kinetics; D008954:Models, Biological; D010573:Pesticide Residues / Q000378:metabolism*; D010600:Pharmacology; D051381:Rats; D014116:Toxicology
D001965:Bromides; D010573:Pesticide Residues