Delayed cutaneous hypersensitivity in patients with prostatic adenocarcinoma.
Cell-mediated immunocompetence of patients seen for followup of adenocarcinoma of the prostate is evaluated using dinitrochlorobenzene as a contact sensitizing agent. The immune status is correlated with the presence or absence of metastatic disease. A highly significant correlation is found between the lack of immune response and the presence of metastatic carcinoma, suggesting that immunotherapy will be useful in the treatment of carcinoma of the prostate.
D000230:Adenocarcinoma / Q000276:immunology*; D000368:Aged; D004137:Dinitrochlorobenzene / Q000276:immunology; D005500:Follow-Up Studies; D006801:Humans; D006968:Hypersensitivity, Delayed; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011471:Prostatic Neoplasms / Q000276:immunology*
D004137:Dinitrochlorobenzene