Mangement of squamous cell carcinoma of the oral tongue and floor of mouth after excisional biopsy.
A review of the records of 23 patients with squamous cell carcinoma of the oral tongue and floor of mouth treated with irradiation after excisional biopsy has shown that: (a) Radiotherapy, primarily using interstitial radium implants, results in excellent local control of the primary area (100%) with preservation of function. (b) The frequency and severity of soft-tissue and bone necrosis may be reduced by not exceeding 5,500-6,000 rads from radium implants when only subclinical aggregates of cancer cells are probably present. (c) Theincidence of subsequent neck disease is low-8.7% (2 of 23 patients), and does not warrant routine elective irradiation of the cervical lymphatics.
D000328:Adult; D000368:Aged; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006050:Gold Radioisotopes / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality; D008297:Male; D008336:Mandibular Diseases / Q000209:etiology; D008875:Middle Aged; D009060:Mouth Floor; D009062:Mouth Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D009336:Necrosis / Q000209:etiology; D009362:Neoplasm Metastasis; D010025:Osteoradionecrosis / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage; D011883:Radium / Q000627:therapeutic use; D014062:Tongue Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery
D006050:Gold Radioisotopes; D011883:Radium