Effects of regional intravenous anaesthesia on blood flow.
Forearm blood flow after regional i.v. anaesthesia in volunteers was compared with the predicted blood flow after arterial occlusion alone, using venous occlusion plethysmography. After arterial occlusion alone for 20 min, marked hyperaemia occured after cuff release. Flows returned to normal within 5 min. Both prilocaine and bupivacaine reduced the hyperaemic response to arterial occlusion. Forearm muscle paralysis using gallamine triethiodide was also associated with a statistically significant but smaller reduction in the hyperaemic response.
D000328:Adult; D000771:Anesthesia, Intravenous; D001783:Blood Flow Velocity; D002045:Bupivacaine / Q000494:pharmacology*; D006801:Humans; D009407:Nerve Block; D010991:Plethysmography; D011318:Prilocaine / Q000494:pharmacology*; D012039:Regional Blood Flow / Q000187:drug effects*
D011318:Prilocaine; D002045:Bupivacaine