Association of cleft lip and atrial septal defect in mice: a preliminary report.
Newborn A/J and CL/Fr mice with congenital cleft lip usually have an atrial septal defect of the secundum type, often associated with cyanosis. Their littermates without cleft lip rarely have a septal defect. The atrial septal defect results from a delay in growth of the atrial septum primum.
D000015:Abnormalities, Multiple; D000818:Animals; D001835:Body Weight; D002971:Cleft Lip / Q000150:complications*; D003490:Cyanosis / Q000209:etiology; D004374:Ductus Arteriosus, Patent; D005865:Gestational Age; D006325:Heart Atria / Q000196:embryology; D006344:Heart Septal Defects, Atrial / Q000150:complications*; D051379:Mice; D008815:Mice, Inbred Strains; D001261:Pulmonary Atelectasis