Is the determination of AHF activity feasible for individual cryoprecipitates?
A method is described in which the factor VIII (AHF) activity of 40 individual cryoprecipitates can be determined within 4 h.  The reagents employed do not require plasma congenitally deficient in factor VIII.  The preparation of cryoprecipitates with known biological activity should result in a more rational use of this type of factor VIII concentrate.
D001771:Blood Banks; D011232:Chemical Precipitation; D003080:Cold Temperature; D003365:Costs and Cost Analysis; D005169:Factor VIII / Q000378:metabolism*; D006801:Humans; D007202:Indicators and Reagents; D010949:Plasma / Q000378:metabolism; D011517:Prothrombin Time; D013925:Thromboplastin / Q000032:analysis; D013997:Time Factors
D007202:Indicators and Reagents; D005169:Factor VIII; D013925:Thromboplastin