Investigation of cranial and other nerves in the mouse with muscular dystrophy.
In the muscular dystrophic mouse mutant there is an absence of Schwann cells over circumscribed lengths of all cranial nerves except for II (I was not examined) and the lesion involves the sympathetic system. Where present, Schwann cells do not produce myelin of normal thickness. The lesion is similar to that described for the spinal roots. Causation is discussed.
D000010:Abducens Nerve / Q000473:pathology; D000818:Animals; D001369:Axons / Q000473:pathology; D002572:Cervical Plexus / Q000473:pathology; D003391:Cranial Nerves / Q000473:pathology* / Q000648:ultrastructure; D005154:Facial Nerve / Q000473:pathology; D005930:Glossopharyngeal Nerve / Q000473:pathology; D051379:Mice; D008815:Mice, Inbred Strains; D009137:Muscular Dystrophy, Animal / Q000473:pathology*; D009186:Myelin Sheath / Q000473:pathology; D009802:Oculomotor Nerve / Q000473:pathology; D009900:Optic Nerve / Q000473:pathology; D012583:Schwann Cells / Q000473:pathology; D014276:Trigeminal Nerve / Q000473:pathology; D014630:Vagus Nerve / Q000473:pathology