Evidence of recessive inheritance of myopia.
Data are presented on the family distribution of nearsightedness, including the frequency of the disorder in the children of two myopes. The previous literature is reviewed, embracing several quantitative family or population studies in addition to extensive pedigree material. It is concluded that there is substantial evidence that recessive inheritance is the principal mechanism of transmission, and that most instances of myopia probably fall into that category.
D005260:Female; D005808:Genes, Recessive; D006801:Humans; D008297:Male; D009216:Myopia / Q000235:genetics*; D010375:Pedigree