Adaptive changes in delta 9 desaturase activity in rat liver.
The delta 9 desaturase activity and the 14-C radioactivity of the de novo synthesized fatty acids incorporated into microsomal lipids and serum triglycerides were measured under different nutritional conditions. The results obtained indicate a correlation between the values of the three parameters studied after starvation or after refeeding Purina chow or either a high carbohydrate or a high protein diet. These data suggest that liver lipogenesis and delta 9 desaturase activities respond to the same regulatory factors.
D000085:Acetates / Q000378:metabolism; D000818:Animals; D002250:Carbon Radioisotopes; D004040:Dietary Carbohydrates; D004044:Dietary Proteins; D044943:Fatty Acid Desaturases / Q000378:metabolism*; D005227:Fatty Acids / Q000096:biosynthesis; D008055:Lipids / Q000096:biosynthesis; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology* / Q000378:metabolism; D051381:Rats; D013217:Starvation; D014280:Triglycerides / Q000097:blood
D000085:Acetates; D002250:Carbon Radioisotopes; D004040:Dietary Carbohydrates; D004044:Dietary Proteins; D005227:Fatty Acids; D008055:Lipids; D014280:Triglycerides; D044943:Fatty Acid Desaturases