Experimental infection of lambs with an aerosol of Pasteurella haemolytica.
Specific pathogen free lambs were exposed to an aerosol of Pasteurella haemolytica. Ten lambs vaccinated with an adjuvanted killed P haemolytica vaccine and nine units of P haemolytica administered in an aerosol. Pneumonia histologically indistinguishable from natural pneumonic pasteurellosis occurred in one vaccinated lamb and in four control lambs.
D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000336:Aerosols; D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage; D007279:Injections, Subcutaneous; D008168:Lung / Q000382:microbiology / Q000473:pathology; D009077:Mucins / Q000494:pharmacology; D010325:Pasteurella / Q000276:immunology / Q000302:isolation & purification; D010326:Pasteurella Infections / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D011014:Pneumonia / Q000382:microbiology / Q000473:pathology / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology / Q000473:pathology; D014611:Vaccination / Q000662:veterinary
D000276:Adjuvants, Immunologic; D000336:Aerosols; D001428:Bacterial Vaccines; D009077:Mucins