Urinary excretion of the sulphate and glucuronide of 3-methoxy-4-hydroxyphenylethyleneglycol in a manic-depressive patient.
The sulphate and glucuronide conjugates of 4-OH-3-methoxyphenylethyleneglycol (MOPEG) and 4-OH-3-methoxymandelic acid (VMA) have been serially studied in the urine of a manic-depressive patient before and after a therapeutic response to lithium carbonate. Excretion of both conjugates correlates with changes in mood. Some reasons to suggest that the sulphate might be a more useful measure of brain activity are stated.
D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy / Q000652:urine*; D004644:Emotions; D005260:Female; D006018:Glycols / Q000652:urine*; D006801:Humans; D008094:Lithium / Q000627:therapeutic use; D009043:Motor Activity; D013431:Sulfates; D014642:Vanilmandelic Acid / Q000652:urine*
D006018:Glycols; D013431:Sulfates; D014642:Vanilmandelic Acid; D008094:Lithium