[Analysis of the hypolipemic, hypocholesteremic and platelet anti-aggregating effects of tibric acid].
Tibric acid shows interesting hypocholesteremic and hypolipemic activity greater than that of clofibrate. In addition high concentrations of tibric acid affect platelet aggregation. Tibric acid does not show choleretic activity and does not affect liver function.
D000818:Animals; D000924:Anticholesteremic Agents; D001565:Benzoates / Q000494:pharmacology*; D001646:Bile / Q000378:metabolism; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy; D002994:Clofibrate / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical; D000960:Hypolipidemic Agents; D008099:Liver / Q000187:drug effects; D010880:Piperidines / Q000494:pharmacology*; D010973:Platelet Adhesiveness / Q000187:drug effects*; D010974:Platelet Aggregation / Q000187:drug effects*; D051381:Rats; D013450:Sulfones / Q000494:pharmacology; D014562:Caudata
D000924:Anticholesteremic Agents; D001565:Benzoates; D000960:Hypolipidemic Agents; D010880:Piperidines; D013450:Sulfones; D002994:Clofibrate
Analisi degli effetti ipolipidemizzanti, ipocolesterolemizzanti ed antiaggreganti piastrinici dell'actibrico