Interaction of malonaldehyde with collagen. III. Binding site characteristic of malonaldehyde with respect to collagen.
In this paper have been studied properties of a product that arose from the interaction of malonaldehyde with collagen. It has been shown by an amino acid analysis that malonaldehyde reacts in a significant way on lysine and tyrosine residues. The partcipation of tyrosine in the reaction with malonaldehyde has been further demonstrated by means of spectrophotometry. It has also been found that the hydrolysis by pronase is considerably modified with the cross linked collagen.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001665:Binding Sites; D002417:Cattle; D003094:Collagen; D006868:Hydrolysis; D007202:Indicators and Reagents; D008314:Malonates; D008315:Malondialdehyde; D010455:Peptides; D013050:Spectrometry, Fluorescence
D000596:Amino Acids; D007202:Indicators and Reagents; D008314:Malonates; D010455:Peptides; D008315:Malondialdehyde; D003094:Collagen