Tuberose sclerosis with malignant astrocytoma.
A case is described of a recurrent malignant gemistocytic astrocytoma in which a diagnosis of tuberose sclerosis was made at post-mortem examination, when "rhabdomyomata" were found in the cardiac muscle and tubers in the cerebral hemispheres. Malignant degeneration of a cerebral lesion has not been described in association with tuberose sclerosis.
D001254:Astrocytoma / Q000150:complications* / Q000473:pathology; D001344:Autopsy; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology; D002675:Child, Preschool; D006338:Heart Neoplasms / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D009206:Myocardium / Q000473:pathology; D012207:Rhabdomyoma / Q000473:pathology; D013702:Temporal Lobe / Q000473:pathology; D014402:Tuberous Sclerosis / Q000150:complications* / Q000473:pathology