Familial trisomy 7 mosaicism.
A trisomy 7 mosaicism (46, XX/47, XX+7) was identified by quinacrine mustard fluorescence studies in a psychiatric patient and in her daughter who also had mental illness. The aetiology of the trisomy 7 mosaicism in two generations of this family is postulated to involve an autosomal dominant gene as initially described by Zellweger and Abbo in 1965.
D002875:Chromosomes; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000648:ultrastructure; D001523:Mental Disorders / Q000235:genetics; D009030:Mosaicism; D010375:Pedigree; D010641:Phenotype; D012732:Sex Determination Analysis; D014314:Trisomy