Effects of iproniazid on chick development.
New Hampshire eggs were injected with iproniazid into the yolk sac at day 2 of incubation by means of a tiny hole in the shell. A control group was injected with normal saline and a second group was left unopened. Iproniazid in the doses we used proved to be lethal for approximately 50% of the chick embryos, while we cannot demonstrate other developmental alterations, either in the macroscopical or in the serial histological study.
D000818:Animals; D002642:Chick Embryo / Q000187:drug effects* / Q000254:growth & development; D003864:Depression, Chemical; D007490:Iproniazid / Q000008:administration & dosage / Q000494:pharmacology* / Q000633:toxicity; D012965:Sodium Chloride / Q000008:administration & dosage; D013268:Stimulation, Chemical
D012965:Sodium Chloride; D007490:Iproniazid