[Haemolysis after heart valve replacement (author's transl)].
Intravascular haemolysis is frequently seen in patients after heart valve replacement, but is often compensated. The cause of the haemolysis is traumatic damage of the red cells. It is more often seen after aortic, than after mitral replacement, because the transvalvular pressure gradient is higher and is more severe in ball valves than in disc valves. If substitution therapy with iron, folic acid, or even red cells fails, re-operation should be seriously considered.
D000743:Anemia, Hemolytic / Q000097:blood / Q000188:drug therapy / Q000209:etiology; D001021:Aortic Valve / Q000601:surgery; D001663:Bilirubin / Q000097:blood; D005492:Folic Acid / Q000627:therapeutic use; D006242:Haptoglobins; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006454:Hemoglobins; D006461:Hemolysis; D006801:Humans; D007501:Iron / Q000097:blood / Q000627:therapeutic use; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008943:Mitral Valve / Q000601:surgery; D011183:Postoperative Complications
D006242:Haptoglobins; D006454:Hemoglobins; D005492:Folic Acid; D007501:Iron; D007770:L-Lactate Dehydrogenase; D001663:Bilirubin
Hämolyse nach Herzklappennersatz