Positional isomer of the muscle relaxant dantrolene.
3-[[5-(P-Nitrophenyl) furfurylidene]amino]hydantoin, a position isomer of dantrolene, was synthesized and evaluated for skeletal muscle relaxant activity.
D000818:Animals; D003620:Dantrolene / Q000138:chemical synthesis / Q000494:pharmacology* / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D006827:Hydantoins / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects; D009125:Muscle Relaxants, Central; D051381:Rats; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D006827:Hydantoins; D009125:Muscle Relaxants, Central; D003620:Dantrolene