Gm(1) and Gm(2) immunoglobulin allotypes in patients with malignant melanoma.
Gm allotype markers were determined in sera from 71 melanoma patients and 400 control persons. There was no significant difference between both groups in Gm distribution. The results were compared to a recent report. Furthermore, in 25 malanoma patients the capacity of serum to interfere with cell-mediated cytotoxicity (CMC) of autologous lymphocytes was determined and related to the Gm allotype.
D002460:Cell Line; D003601:Cytotoxicity Tests, Immunologic; D005828:Genetics, Population; D005860:Germany, West; D006801:Humans; D007126:Immunoglobulin Allotypes; D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G / Q000032:analysis; D008214:Lymphocytes / Q000276:immunology; D008545:Melanoma / Q000235:genetics* / Q000276:immunology
D007126:Immunoglobulin Allotypes; D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G