Dietary vitamin A and human lung cancer.
Five-year follow-up results for 8,278 men who in mail surveys had reported their cigarette smoking and dietary habits showed: (1) an index for vitamin A intake to be negatively associated with lung cancer incidence at all levels of cigarette smoking;(2) this association to be more clearly expressed in the subset of histologically proven pulmonary carcinomas other than adenocarcinoma; and (3) the positive association between cigarette smoking and lung cancer to obtain irrespective of the dietary level of vitamin A or related factors. The findings are in accordance with experimental results on animals and call for further exploration of the role of nutritional factors in the development of human lung cancer.
D000230:Adenocarcinoma; D000368:Aged; D002277:Carcinoma; D005247:Feeding Behavior; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D008875:Middle Aged; D012907:Smoking; D014801:Vitamin A
D014801:Vitamin A