Studies on morphine analgesia.
Several agents with specific action on biologically active substances in brain were investigated for their influence on morphine analgesia. It was observed that imipramine, chlorpheniramine, and haloperidol antagonized morphine analgesia. The probable mechanism of action has been discussed.
D000698:Analgesia; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002110:Caffeine / Q000494:pharmacology; D002744:Chlorpheniramine / Q000494:pharmacology; D006220:Haloperidol / Q000494:pharmacology; D007099:Imipramine / Q000494:pharmacology; D009020:Morphine / Q000037:antagonists & inhibitors*; D010646:Phentolamine / Q000494:pharmacology; D051381:Rats; D011930:Reaction Time / Q000187:drug effects*
D002110:Caffeine; D002744:Chlorpheniramine; D009020:Morphine; D001285:Atropine; D006220:Haloperidol; D007099:Imipramine; D010646:Phentolamine