Effects of nitrous oxide on decision-strategy and sustained attention.
Effects of 10,20, and 30% N2O on decision-making strategy, reaction-times, sustained attention, the Digit Symbol Subsititution Test (DSST), short-term memory and the Clyde Mood Scale were assessed in 12 test subjects. Decision-making strategy, as measured by 2-choice probability-learning, was unaffected by 30% N2O once a strategy had been formulated, but reaction-times were increased. Sustained attention was significantly affected in 33% of our subjects, whereas performance on the DSST and on the short-term memory task was impaired in virtually all subjects. Changes were noted in several mood-scale factors with 30% N2O. No residual drug effects were found.
D000293:Adolescent; D000328:Adult; D001288:Attention / Q000187:drug effects*; D003657:Decision Making / Q000187:drug effects*; D004644:Emotions / Q000187:drug effects; D006801:Humans; D007257:Information Theory; D008297:Male; D008570:Memory, Short-Term / Q000187:drug effects; D009609:Nitrous Oxide / Q000494:pharmacology*; D011337:Probability Learning / Q000187:drug effects; D011930:Reaction Time / Q000187:drug effects
D009609:Nitrous Oxide