Apomorphine: facilitation of sexual behaviour in female rats.
Sexual receptivity of spayed female rats was studied by recording lordosis responses to a mounting male. Administration of apomorphine (0.25 mg/kg) to oestrogen+progesterone-primed females produced an increase in lordosis behaviour 2--48 hr after injection. An increase was also found when apomorphine was substituted for progesterone. These results suggest a role for dopamine in controlling sexual receptivity.
D000311:Adrenal Glands / Q000502:physiology; D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D004967:Estrogens / Q000494:pharmacology; D005260:Female; D011374:Progesterone / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D013268:Stimulation, Chemical; D013997:Time Factors
D004967:Estrogens; D011374:Progesterone; D001058:Apomorphine