A rapid micro culture method of chromosome preparations from fibroblasts and amniotic cells.
A micromethod enabling the making of chromosome preparations from fibroblasts and amniotic cells cultured on surface-treated Microtest II plates is presented. Preparations from each well contain sufficient metaphases to perform a reliable diagnosis. The potential for the use of this method in early prenatal diagnosis is discussed.
D000653:Amniotic Fluid / Q000166:cytology*; D002478:Cells, Cultured; D002875:Chromosomes; D005347:Fibroblasts / Q000166:cytology*; D006801:Humans; D007621:Karyotyping / Q000379:methods*; D011296:Prenatal Diagnosis / Q000379:methods