[Serotonin metabolism in acute renal ischemia in rabbits].
In tissue of ischemic kidney of rabbits a 5-hydroxytryptophan decarboxylase activity was decreased at first 15 min of ischemia; in contralateral kidney it was slightly increased. Then, within all the studied periods (24 hrs), activity of the enzyme was gradually decreased in both kidneys. The monoamine oxidase activity (substrates serotonin and p-nitrophenyl ethylamine) changed alternatively in early periods of ischemia; it tended to increase, especially in contralateral kidney, within 3 hrs after constriction of kidney artery.
D000208:Acute Disease; D000818:Animals; D004796:Clinical Enzyme Tests; D004296:Dopa Decarboxylase / Q000378:metabolism; D004789:Enzyme Activation; D004794:Enzyme Repression; D007511:Ischemia / Q000378:metabolism*; D007668:Kidney / Q000098:blood supply* / Q000201:enzymology; D008026:Ligation; D008995:Monoamine Oxidase / Q000378:metabolism; D011817:Rabbits; D012077:Renal Artery; D012701:Serotonin / Q000378:metabolism*; D013997:Time Factors
D012701:Serotonin; D008995:Monoamine Oxidase; D004296:Dopa Decarboxylase
Obmen serotonina pri ostroĭ pochechnoĭ ishemii u krolikov