Panniculitis (Rothmann-Makai), with good response to tetracycline.
A case of idiopathic cirucumscribed panniculitis of the legs, with features consistent with that of the Rothmann-Makai syndrome, is reported. The response to a 10-week course of oral tetracycline therapy was impressive. It is suggested that the anti-lipase activity of tetracycline could account for this response.
D000284:Administration, Oral; D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D008049:Lipase / Q000037:antagonists & inhibitors; D010201:Panniculitis, Nodular Nonsuppurative / Q000188:drug therapy* / Q000473:pathology; D013752:Tetracycline / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*
D008049:Lipase; D013752:Tetracycline