[Late toxicoses of pregnancy and transplacental transmission of antituberculosis antibodies].
The content of antituberculosis antibodies in the blood of neonates was studied with the aid of passive hemagglutination test (PHT) after Boiden and in the PHT modified after Middlebrook-Dubot. The use of a complex antigen from the BCG vaccine in the PHT proved to possess the greatest prospects; antituberculosis humoral antibodies were detected at the time of birth in 48.5% of the children. A total of 322 neonates, including 167 neonates born of mothers with late toxemia of pregnancy, were examined. With the given complication of pregnancy there was revealed a disturbance of the transplacental transmission of antituberculosis antibodies, this being explaining by the destructive-sclerotic changes in the placental tissue in marked toxemia of pregnancy.
D000907:Antibodies, Bacterial / Q000032:analysis*; D001769:Blood; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D011225:Pre-Eclampsia / Q000276:immunology*; D011247:Pregnancy; D014376:Tuberculosis / Q000276:immunology*; D014470:Umbilical Cord
D000907:Antibodies, Bacterial
Pozdnil toksikoz beremennykh i transplatsentarnaia peredacha protivotuberkuleznykh antitel