[Anticardiac antibodies, cross reacting with the membranes of streptococcus, in protracted rheumatic fever].
The anti-cardiac antibodies cross-reacting with the Streptococcal membranes were studied by the method of Zabriskie and co-authors in 162 patients with rheumatism in its active phase and in 181 control individuals. The anti-cardiac antibodies were found in over half of the rheumatic patients and far less frequently in the controls. At the same time in the majority of cases only those anti-cardiac antibodies that were found in the rheumatics possessed distinct cross-activity towards the A-streptococcal membranes. Most consistently were they found in those with a protracted course of the disease.
D000907:Antibodies, Bacterial; D001323:Autoantibodies / Q000032:analysis*; D002462:Cell Membrane / Q000276:immunology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology; D012213:Rheumatic Fever / Q000276:immunology*; D012214:Rheumatic Heart Disease / Q000276:immunology*; D012595:Scleroderma, Systemic / Q000276:immunology; D013291:Streptococcus / Q000276:immunology*
D000907:Antibodies, Bacterial; D001323:Autoantibodies
Protivokardial'nye antitela, perekrestno reagiruiushchie s membranami streptokokka, pri zatiazhnom revmatizme