Use of the sphygmomanometer ASE-1 for the indirect measurement of blood pressure in the rat.
Appropriate conditions for the indirect measurement of blood pressure in rat were determined. The value of 0.78 was found as a correlation factor between the direct and the indirect measurement methods. The direct and indirect methods were compared on hypertensive phenylephrine effects. Good dose-effect correlation of hydralazine by the indirect measurement was found. Our results indicate that the indirect measurement is suitable for the determination of hyper- and hypotensive drugs.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D001795:Blood Pressure Determination / Q000295:instrumentation*; D004582:Electronics, Medical; D005260:Female; D006830:Hydralazine / Q000008:administration & dosage / Q000494:pharmacology; D008365:Manometry / Q000295:instrumentation; D008722:Methods; D010656:Phenylephrine / Q000494:pharmacology; D011674:Pulse; D051381:Rats
D010656:Phenylephrine; D006830:Hydralazine