Distribution of concanavalin A receptor sites on specific populations of embryonic cells.
The early 32- to 64-cell stage of the sea urchin embryo consists of three cell types, easily distinguishable by size: micromeres, mesomeres, and macromeres. Only the micromeres are migratory. Treatment of dissociated sea urchin embryo cells with fluorescein-labeled concanavalin A (Con A) revealed a Con A-induced highly clustered or capped distribution of receptor sites on the micromeres. Concanavalin A did not induce significant clustering or capping of receptor sites on the mesomeres or macromeres. The results indicate that Con A receptor sites are more mobile on specific population of malignant-like migratory embryonic cells.
D000818:Animals; D001666:Binding Sites, Antibody; D002462:Cell Membrane / Q000378:metabolism; D003208:Concanavalin A; D004625:Embryo, Nonmammalian / Q000166:cytology / Q000276:immunology*; D011955:Receptors, Drug; D012617:Sea Urchins
D011955:Receptors, Drug; D003208:Concanavalin A