Gas chromatography and mass spectrometry of derivatives of amino acids. Oxazolin-5-ones of several acyl-leucines.
By the action of dicyclohexylcarbodiimide on fourteen different acyl-leucines in ethyl acetate solution, the corresponding oxazolin-5-ones were formed. The reaction was quantitative and very rapid. The oxazolin-5-ones were separated on a gas chromatograph on OV-7 and EGA columns. The mass spectra of the oxazolin-5-ones showed characteristic fragments that could be used for identification.
D000215:Acylation; D002849:Chromatography, Gas; D007930:Leucine / Q000031:analogs & derivatives*; D013058:Mass Spectrometry; D008722:Methods; D010080:Oxazoles / Q000032:analysis* / Q000138:chemical synthesis; D010081:Oxazolone / Q000031:analogs & derivatives / Q000032:analysis*
D010080:Oxazoles; D010081:Oxazolone; D007930:Leucine