Effect of atropine in reducing plasma protein shedding by the canine oxyntic glandular mucosa induced by topical irrigation with histamine or cobra venom.
The shedding of plasma protein by the canine oxyntic glandular mucosa induced by topical irrigation of the mucosa with a solution of histamine after the gastric mucosal barrier is broken is reduced by intravenous administration of atropine. Plasma shedding induced by repeated irrigation of the normal mucosa with solutions of Naja naja venom is likwise reduced by intravenous atropine. The nature of atropine-sensitive component of plasma shedding is unknown.
D000818:Animals; D001285:Atropine / Q000008:administration & dosage / Q000494:pharmacology*; D001798:Blood Proteins / Q000502:physiology*; D003714:Denervation; D004285:Dogs; D005753:Gastric Mucosa / Q000098:blood supply / Q000187:drug effects*; D006632:Histamine / Q000494:pharmacology*; D007263:Infusions, Parenteral; D009934:Organization and Administration; D012910:Snake Venoms / Q000494:pharmacology*; D013270:Stomach / Q000502:physiology / Q000601:surgery; D007507:Therapeutic Irrigation; D014628:Vagotomy; D014688:Venoms / Q000494:pharmacology*
D001798:Blood Proteins; D012910:Snake Venoms; D014688:Venoms; D001285:Atropine; D006632:Histamine