HL-A8: a genetic link with thyrotoxicosis.
The incidence of HL-A8 was significantly increased in 64 Caucasian patients with thyrotoxicosis compared with 700 Australian blood donors (42% versus 24%). No significant correlation was observed between HL-A8 and autoantibodies to thyroid components in thyrotoxic patients; thus the association of HL-A8 must be either with the disease itself, or possibly with immune responses not tested for this study.
D001323:Autoantibodies; D001782:Blood Donors; D008040:Genetic Linkage; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006650:Histocompatibility Testing; D006801:Humans; D006980:Hyperthyroidism / Q000235:genetics*
D001323:Autoantibodies; D006680:HLA Antigens; D006649:Histocompatibility Antigens