The clinical significance of systolic murmurs in the elderly.
A group of 278 patients, over the age of 60 years, and representative of geriatric and general medical admissions to the District General Hospital in Banbury, Oxforshire, was studied to correlate the prevalence of systolic murmurs to age, sex, cardiac failure, ischaemic heart disease, dysrrhythmias, hypertension, peripherial vascular disease and anaemia. The object was to establish the clinical significance of these murmurs and test a postulate that they could not be dismissed as benign. Seventy-five per cent of the murmurs were judged to be aortic and 12 per cent mitral in origin. The prevalence of systolic murmurs increased with age from 32 per cent at 60-64 years to 57 per cent over 85 years, and was greater in females (44 per cent) than in males (34 per cent). The presence of systolic murmurs was related to the presence of cardiac failure, ischaemic heart disease, dysrrhythmias, hypertension, peripheral vascular disease and anemia. Only 8 per cent of patients with systolic murmurs had none of the above-mentioned six cardiovascular abnormalities compared with 36 per cent of patients without such a murmur, while multiple cardiovascular abnormalities were also commoner in the former group. The mortality rate in hospital was similar for patients with or without a systolic murmur.
D000367:Age Factors; D000368:Aged; D000740:Anemia / Q000175:diagnosis; D001024:Aortic Valve Stenosis / Q000175:diagnosis; D001145:Arrhythmias, Cardiac / Q000175:diagnosis; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000453:epidemiology; D003937:Diagnosis, Differential; D004739:England; D005260:Female; D006326:Heart Auscultation; D006333:Heart Failure / Q000175:diagnosis; D006337:Heart Murmurs; D006801:Humans; D006974:Hypertension, Malignant / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000175:diagnosis; D014262:Tricuspid Valve Insufficiency / Q000175:diagnosis; D014652:Vascular Diseases / Q000175:diagnosis