The base-pairing specificity of cellulose-pdT9.
The stability of the interaction of oligoadenylates, containing single nucleotide substitutions, with cellulose-pdT9 has been studied by thermal elution. In the case of oligodeoxyriboadenylates, the replacement of an internal dA by dC, dG or dT caused destabilization. In the case of oligoriboadenylates, replacement of an internal A residue by C or U resulted in a significantly lesser destabilization. The results indicate that caution should be exercised in extrapolation of data on the specificity of deoxyribonpolynucleotide-deoxyribopolynucleotide hybridization to structure of the type deoxyribopolynucleotide-ribopolynucleotide.
D000227:Adenine Nucleotides; D001483:Base Sequence; D002482:Cellulose; D055598:Chemical Phenomena; D002621:Chemistry; D003854:Deoxyribonucleotides; D004355:Drug Stability; D008837:Micrococcus / Q000201:enzymology; D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides; D011119:Polynucleotides; D011117:Polyribonucleotide Nucleotidyltransferase; D013942:Thymine Nucleotides
D000227:Adenine Nucleotides; D003854:Deoxyribonucleotides; D009841:Oligonucleotides; D011119:Polynucleotides; D013942:Thymine Nucleotides; D002482:Cellulose; D011117:Polyribonucleotide Nucleotidyltransferase