[Use of glucagon for the treatment of acute cardiac insufficiency during open-heart surgery].
The results of the employment of glukagon in 40 patients operated upon under extracorporeal circulation for acquired and congenital heart diseases are presented. Instrumental studies of the haemodynamics in 11 cases demonstrated that glukagon in a dose of 3 mg produced in most cases an increase of the cardiac output and stroke volume, and of the systolic index by over 20%, with the heart rate increasing insignificantly. Clinical observations conducted in 29 patients demonstrated a high efficacy of glukagon in the management of acute cardiac failure and low cardiac output syndrome in the early post-perfusion period.
D000208:Acute Disease; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D005934:Glucagon / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D006321:Heart / Q000503:physiopathology; D006323:Heart Arrest / Q000188:drug therapy / Q000628:therapy*; D006330:Heart Defects, Congenital / Q000601:surgery; D006331:Heart Diseases / Q000601:surgery; D006333:Heart Failure / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male
D005934:Glucagon
Primenenie gliukagona dlia lecheniia ostroĭ serdechnoĭ nedostatochnosti pri operatsiiakh na otkrytom serdtse