Proceedings:   Cephazolin in obstetrics.
The pharmacodynamics of a new cephalosporin--cephazolin--have been evaluated in clinical obstetrics with particular reference to antibiotic prophylaxis for the cardiac patient, and the prophylaxis and treatment of choriamnionitis and intrauterine pneumonia.  Cephazolin effectively crosses the placental barrier.  It slowly concentrates in the amniotic fluid when the fetus is alive.  This new drug  may be used for phophylactic cover in the above clinical situations.
D000653:Amniotic Fluid / Q000032:analysis; D001424:Bacterial Infections / Q000517:prevention & control*; D002437:Cefazolin / Q000378:metabolism* / Q000627:therapeutic use; D002511:Cephalosporins / Q000378:metabolism*; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005315:Fetal Diseases / Q000517:prevention & control; D006801:Humans; D008431:Maternal-Fetal Exchange; D007744:Obstetric Labor Complications / Q000517:prevention & control*; D011247:Pregnancy
D002511:Cephalosporins; D002437:Cefazolin