Total unilateral renal destruction caused by irradiation for Hodgkin's disease.
Total unilateral renal destruction has been observed in a patient who previously received irradiation for Hodgkin's disease. The clinical features, after a six-year asymptomatic interval, included recurrent calculi and infection in what was subsequently demonstrated radiographically to be a nonfunctioning kidney. The gross and microscopic characteristics of the nephrectomy specimen have been described and correlated with the magnitude of irradiation and the clinical course.
D000328:Adult; D003037:Cobalt Radioisotopes; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male; D011867:Radioisotope Teletherapy / Q000009:adverse effects*; D011878:Radiotherapy / Q000009:adverse effects*
D003037:Cobalt Radioisotopes