Intracavitary irradiation of early rectal cancer for cure. A series of 186 cases.
If radical surgery is the only rational policy for most cases of rectal cancer, the problem of local treatment in poor surgical risk patients should be discussed in selected cases. Only limited, fairly-well-differentiated tumors, still confined to the rectal wall may have a sufficiently low probability of lymphatic spread to be amenable to local treatment. Rectal cancer, usually regarded as being slightly radiosensitive when treated by external irradiation, proves to be highly radiosensitive in the case of early cancer treated by intracavitary irradiation. This method is able to control a large amount of limited polypoid and ulcerative adenocarcinomas. In a series of 133 cases followed more than 5 years, the rate of death from cancer is only 9%, and the 5-year survival rate is 78%. As compared with local exision or electrocoagulation, intracavitary irradiation has several advantages. It does not require colostomy nor anesthesia. Contact x-ray therapy is an ambulatory treatment applicable even to elderly and fragile patients. There is no danger of fistula in the case of tumor of the anterior wall in female patients. It preserves all the chances of cure by subsequent surgery in case of failure.
D000230:Adenocarcinoma / Q000401:mortality / Q000532:radiotherapy; D000368:Aged; D005260:Female; D006801:Humans; D007495:Iridium / Q000008:administration & dosage; D008207:Lymphatic Metastasis; D008297:Male; D008722:Methods; D008875:Middle Aged; D011879:Radiotherapy Dosage; D011883:Radium / Q000008:administration & dosage; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000532:radiotherapy*
D007495:Iridium; D011883:Radium