Effect of UV on cleavage of Xenopus laevis.
UV irradiation of the vegetal pole of stage 2 X. laevis embryos with doses of 6000-18000 ergs/mm-2 delayed or inhibited cytokinesis in the vegetal hemisphere. Nuclear division continued so that a syncytium was formed, the size and persistence of which depended on the dose. Embryos which received a low UV dose were subsequently able to recover whereas embryos receiving a high dose were unable to gastrulate successfully. The implications for investigations into the role of cytoplasmic determinants are discussed.
D000818:Animals; D002467:Cell Nucleus; D004625:Embryo, Nonmammalian / Q000166:cytology / Q000528:radiation effects; D005260:Female; D005306:Fertilization / Q000528:radiation effects*; D008938:Mitosis / Q000528:radiation effects*; D010063:Ovum / Q000166:cytology / Q000528:radiation effects*; D011830:Radiation Effects; D014466:Ultraviolet Rays; D014981:Xenopus