Prevalence of renal disease in asymptomatic heroin addicts.
Renal function was studied in 145 asymptomatic male heroin addicts admitted to a methadone detoxification program. The mean duration of addiction was ten years. Three patients had protein excretion greater than 150 mg/24 hr; in one of these, membranous glomerulonephritis was found. All except one had normal creatinine clearance. Hypertension was present in 2.7%. This study does not support the concept that heroin addiction is associated with a high prevalence of renal disease.
D002641:Chicago; D003401:Creatine / Q000652:urine; D005069:Evaluation Studies as Topic; D006556:Heroin Dependence / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008658:Inactivation, Metabolic; D007674:Kidney Diseases / Q000175:diagnosis / Q000453:epidemiology*; D008691:Methadone / Q000627:therapeutic use; D011507:Proteinuria
D003401:Creatine; D008691:Methadone