The effects of cosmic particle radiation on pocket mice aboard Apollo XVII: V. preflight studies on tolerancee to oxygen and heat. Part III. effects on eyes.
A study was made of the eyes of eight pocket mice exposed to oxygen at partial pressures of 8, 10, or 12 psi over a period of 7 d. At the termination of the exposure, the animals were decompressed to sea-level O2 either immediately or over a period of 30, 60, or 90 min. No pathological changes were found in any of the eyes, except in the retina of one of the animals exposed to 12 psi O2. Here, only a single rod photoreceptor was found damaged, an observation not regarded as significant. Hence, an oxygen partial pressure as high as 12 psi in the camister in which pocket mice were expected to fly on Apollo XVII would probably have no deleterious effect on the eyes of the animals.
D000222:Adaptation, Physiological; D000818:Animals; D001273:Atmosphere Exposure Chambers; D003359:Cosmic Radiation; D004780:Environment, Controlled; D005123:Eye / Q000187:drug effects*; D006358:Hot Temperature; D051379:Mice; D010100:Oxygen / Q000633:toxicity*; D010313:Partial Pressure; D011830:Radiation Effects; D012160:Retina / Q000473:pathology; D013026:Space Flight; D013997:Time Factors; D014481:United States
D010100:Oxygen