Demonstration of a factor in the serum of homozygotes and heterozygotes for cystic fibrosis by a non-biological technique.
A factor has been isolated from serum of homozygotes and obligate heterozgotes for cystic fibrosis using isoelectric focusing and disc electrophoresis as analytical methods. The factor is focused within an IgG-fraction with an isoelectric point of pH 8 to 9 but differs from IgG in its lower molecular weight. It is thus similar to, if not identical with, the ciliary dyskinesia factor.
D001797:Blood Protein Electrophoresis / Q000379:methods; D001798:Blood Proteins / Q000032:analysis*; D003176:Complement C3; D003550:Cystic Fibrosis / Q000097:blood* / Q000235:genetics; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007074:Immunoglobulin G; D007526:Isoelectric Point; D008970:Molecular Weight
D001798:Blood Proteins; D003176:Complement C3; D007074:Immunoglobulin G