Mutant of the yeast Saccharomycopsis lipolytica that accumulates and excretes protorphyrin IX.
The red, water-insoluble pigment excreted by a mutant strain of the yeast Saccharomycopsis lipolytica is show to be protoporphyrin IX. In genetic crosses the red phenotype has the properties characteristic of a defect in a single, recessive nuclear gene. The yield and ease of harvest of protoporphyrin IX from the yeast mutant indicate that this strain or its derivatives may be a valuable source of this substance.
D000085:Acetates / Q000494:pharmacology; D001203:Ascomycota / Q000378:metabolism*; D003227:Conjugation, Genetic; D003470:Culture Media / Q000494:pharmacology; D005947:Glucose / Q000494:pharmacology; D006838:Hydrocarbons / Q000494:pharmacology; D009154:Mutation; D009829:Oleic Acids / Q000494:pharmacology; D010641:Phenotype; D010858:Pigmentation / Q000187:drug effects; D011166:Porphyrins / Q000032:analysis* / Q000378:metabolism*; D011524:Protoporphyrins / Q000032:analysis* / Q000096:biosynthesis / Q000378:metabolism*; D012442:Saccharomycopsis / Q000378:metabolism*; D013057:Spectrum Analysis; D013501:Surface-Active Agents / Q000494:pharmacology
D000085:Acetates; D003470:Culture Media; D006838:Hydrocarbons; D009829:Oleic Acids; D011166:Porphyrins; D011524:Protoporphyrins; D013501:Surface-Active Agents; D005947:Glucose