Truncal vagotomy and pyloroplasty for duodenal ulcer.
Two hundred sixty-five patients who underwent vagotomy and pyloroplasty for duodenal ulcer disease were observed postoperatively, 220 for two to ten years, with an average follow-up of five years. Vagotomy and pyloroplasty carried a higher overall recurrence rate (3.6%) than did subtotal gastrectomy and vagotomy (1%), largely because of the high ulcer recurrence rate more than two years after operation for massive bleeding (9.2%) rather than that following elective operation (1.8%). Thirty-five percent of these patients with recurrent ulcers did well with medical management and did not require a second operation. The mortality of vagotomy and pyloroplasty for a massively bleeding ulcer (11%) was less than that following subtotal gastrectomy (21%). The mortality of elective vagotomy and pyloroplasty was 1%.
D000328:Adult; D000368:Aged; D004381:Duodenal Ulcer / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy; D005774:Gastrostomy; D006801:Humans; D007328:Insulin; D008297:Male; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000601:surgery; D011183:Postoperative Complications / Q000453:epidemiology / Q000401:mortality; D011708:Pylorus / Q000601:surgery*; D011859:Radiography; D012008:Recurrence; D013270:Stomach / Q000000981:diagnostic imaging; D014628:Vagotomy / Q000379:methods; D014630:Vagus Nerve / Q000033:anatomy & histology
D007328:Insulin