Some behavioral effects of transecting ventral or dorsal fiber connections of the septum in the rat.
The behavioral effects of large electrolytic lesions in the septal area were compared with those of knife cuts that severed the ventral or dorsal connections of this structure. Rats with septal lesions lost weight and were transiently hyperdipsic. Ventral cuts produced similar effects, but dorsal cuts did not. All three operations decreased the latency to eat in a novel environment, increased the intake of sweetened milk, enhanced acquisition of a food-rewarded running response, and facilitated acquisition of a shuttle box avoidance response, The lesion, but neither of the knife cuts, reduced the effects of punishment and impaired the acquisition of a one-way avoidance response.
D000818:Animals; D001362:Avoidance Learning / Q000502:physiology; D001522:Behavior, Animal / Q000502:physiology*; D001835:Body Weight; D003216:Conditioning, Operant; D004327:Drinking Behavior / Q000502:physiology; D004597:Electroshock; D005108:Extinction, Psychological; D005247:Feeding Behavior / Q000502:physiology; D007031:Hypothalamus; D008297:Male; D009043:Motor Activity / Q000502:physiology; D009410:Nerve Degeneration; D010775:Photic Stimulation; D011678:Punishment; D051381:Rats; D011930:Reaction Time; D012201:Reward; D012688:Septum Pellucidum / Q000502:physiology*