The influences of methylphenidate on heart rate and behavioral measures of attention in hyperactive children.
Reaction-time performance and heart-rate responses associated with attention were used to assess the hyperactive child's attentional deficit and his response to methylphenidate. Attentional deficits shown by long response latencies were reflected in heart-rate responses theoretically incompatible with sustained attention. Subjects exhibiting the greatest attentional deficit displayed the most favorable response to methylphenidate in both reaction-time performance and physiological measures. However, subjects who showed the greatest improvement in social behavior were those who showed the least improvement in reaction-time performance.
D001288:Attention / Q000187:drug effects*; D002648:Child; D002652:Child Behavior / Q000187:drug effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D006948:Hyperkinesis; D008297:Male; D008774:Methylphenidate / Q000494:pharmacology*; D011930:Reaction Time; D012919:Social Behavior / Q000187:drug effects
D008774:Methylphenidate