Growth effects of tranquilizing agents containing phenothiazine derivatives on barley seedlings-1.
Two prescription tranquilizers reduced the growth of barley plants by as much as 50%. Measurements of the long axis of mid-anaphase cells from shoot meristems did not seem to explain the reduced growth. However, observations from electron micrographs indicated abnormal nuclear membranes would not undergo the usual mitotic divisions which, in turn, could account for the reduction in growth. Futhermore, it is suggested that the opening of the nuclear membrane resulted from enzyme degradation.
D002455:Cell Division / Q000187:drug effects; D002462:Cell Membrane / Q000187:drug effects; D002746:Chlorpromazine / Q000494:pharmacology*; D003864:Depression, Chemical; D002523:Edible Grain / Q000187:drug effects*; D006128:Growth / Q000187:drug effects; D001467:Hordeum / Q000187:drug effects*; D011395:Promazine / Q000494:pharmacology*; D012639:Seeds / Q000187:drug effects
D011395:Promazine; D002746:Chlorpromazine