Fetal and maternal lesions in pregnant ewes ingesting locoweed (Astragalus lentiginosus).
Locoweed (Astragalus lentiginosus) was fed to ewes from 70 to 100 days of pregnancy. Ewes were killed at 100, 115, 130, and 145 days, and selected tissues were collected from both the dam and the fetus for histologic examination. Neurovisceral cytoplasmic vacuolation and neuroaxonal dystrophy decreased in dam and fetus with time after the feeding of locoweed was discontinued.
D000818:Animals; D001369:Axons / Q000473:pathology; D001921:Brain / Q000473:pathology; D005260:Female; D005315:Fetal Diseases / Q000473:pathology / Q000662:veterinary*; D009206:Myocardium / Q000473:pathology; D009474:Neurons / Q000473:pathology; D010939:Plant Poisoning / Q000473:pathology / Q000662:veterinary*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000473:pathology*