Synthesis and biological evaluation of 2-(9-acridinyl)ethyl-N-substituted carbamates and their hydrochlorides and 10-N-oxides.
The syntheses of 2-(9-acridinyl)ethyl-N-substituted carbamates and their hydrochlorides and 10-N-oxides are reported along with biological results in the areas of antineoplastic, antimalarial, and CNS activity screening. The compounds showed negative biological activity in the areas tested.
D000166:Acridines / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D000962:Antimalarials; D000970:Antineoplastic Agents; D002219:Carbamates / Q000138:chemical synthesis / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical; D051379:Mice
D000166:Acridines; D000962:Antimalarials; D000970:Antineoplastic Agents; D002219:Carbamates