Acute renal insufficiency following hydrostatic pressure treatment: comments on technical procedure.
A man with a solitary bladder carcinoma suffered acute tubular necrosis following hydrostatic pressure therapy. The nephrotoxicity caused by antibiotics and/or the septicemic shock seems to be responsible. The animal experiment suggested changes in the technique: 1) the bladder should be overdistended via a Foley catheter with a rubber ballon at the tip to prevent a possible postoperative complication and 2) one should try to decrease rather than maintain the high intravesical pressure during overdistension to avoid bladder wall rupture. The overstretching of a blood vessel alone is quite sufficient to bring the anoxia upon the bladder tumor, which is verfied by the biophysical principle.
D058186:Acute Kidney Injury / Q000209:etiology*; D000818:Animals; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000628:therapy; D004285:Dogs; D006801:Humans; D006874:Hydrostatic Pressure / Q000009:adverse effects*; D007049:Iatrogenic Disease; D008297:Male; D008875:Middle Aged; D011312:Pressure / Q000009:adverse effects*; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000628:therapy; D014546:Urinary Catheterization