Diuretics.
The use of diuretics to treat edema is reviewed. Normal salt and water metabolism is reviewed briefly. The drugs covered are the thiazide diuretics, loop diuretics(ethacrynic acid and furosemide) and distal blocking agents (spironolactone and triamterene). The sites and modes of action, indications, doses, complications and relative costs of these agents are discussed.
D001581:Benzothiadiazines; D004032:Diet; D004232:Diuretics / Q000627:therapeutic use*; D004487:Edema / Q000188:drug therapy*; D004976:Ethacrynic Acid / Q000627:therapeutic use; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D009399:Nephrons / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D013148:Spironolactone / Q000627:therapeutic use; D014223:Triamterene / Q000627:therapeutic use; D014867:Water / Q000378:metabolism
D001581:Benzothiadiazines; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors; D014867:Water; D013148:Spironolactone; D005665:Furosemide; D012964:Sodium; D004976:Ethacrynic Acid; D011188:Potassium; D014223:Triamterene