An analysis of those components of Toxoplasma gondii responsible for delayed hypersensitivity reactions in mice.
Testing of extracts of Toxoplasma gondii (RH strain) indicated that delayed hypersensitivity as manifested by delayed skin reactions and inhibition of macrophage migration was induced only by those fractions containing RNA.
D000818:Animals; D000941:Antigens / Q000302:isolation & purification; D002464:Cell Migration Inhibition; D006968:Hypersensitivity, Delayed; D008264:Macrophages / Q000276:immunology; D051379:Mice; D012313:RNA / Q000276:immunology; D012882:Skin Tests; D014122:Toxoplasma / Q000032:analysis / Q000276:immunology*; D014124:Toxoplasmosis, Animal / Q000276:immunology
D000941:Antigens; D012313:RNA