Mutations induced by X-radiation in the yeast Schizosaccharomyces pombe.
Experiments on strains of yeast with different genetic backgrounds were done to evaluate the kinetics of inactivation and mutation induction by X-radiations. A system of forward mutation induction in five loci was used as a specific mutation rate of 0.14-10-minus 8 times locus times rad was evaluated for the wild type. From a comparison of observations with wild type and radiation-sensitive strains, it may be assumed that, in this yeast, mutations are mainly the result of a repair-active process. The range of genotypic and phenotypic influence upon the specific locus mutation rate was evaluated with appropriate biological material and experiments.
D001203:Ascomycota / Q000528:radiation effects*; D002470:Cell Survival; D002874:Chromosome Mapping; D004260:DNA Repair; D004307:Dose-Response Relationship, Radiation; D005796:Genes; D005838:Genotype; D009154:Mutation; D010641:Phenotype; D011336:Probability; D011831:Radiation Genetics; D012568:Schizosaccharomyces / Q000528:radiation effects*; D014965:X-Rays