[Estradiol-17beta, estrone, LH and FSH in serum after administration of estradiol-17beta, estradiolbenzoate, estradiol-valeriate and estradiol-undecylate in the female (author's transl)].
Estradiol-17beta, estradiol-benzoate, estradiol-valerianate, and estradiol-undecylate were injected intravenously and intramuscularly to postmenopausal woman and to female castrates. Equal doses were used corresponding to 20 mg of free estradiol-17beta. Estradiol-17beta, estrone, FSH and LH were measured in serum by radioimmunoassay before and after application of the hormone and the estradiol esters. Thus the depot effect of the different esters could be compared.
D000328:Adult; D001565:Benzoates / Q000494:pharmacology; D002369:Castration; D004305:Dose-Response Relationship, Drug; D004952:Esters; D004958:Estradiol / Q000031:analogs & derivatives / Q000097:blood*; D004970:Estrone / Q000097:blood*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007044:Hysterectomy; D007247:Infertility, Female / Q000097:blood; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D007986:Luteinizing Hormone / Q000097:blood*; D008593:Menopause; D008875:Middle Aged; D010053:Ovary / Q000601:surgery; D011863:Radioimmunoassay; D013329:Structure-Activity Relationship; D014476:Undecylenic Acids; D014631:Valerates / Q000494:pharmacology
D001565:Benzoates; D004952:Esters; D014476:Undecylenic Acids; D014631:Valerates; D004970:Estrone; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Untersuchungen zur Pharmakokinetik von Ostradiol-17beta, Ostradiol-Benzoat, Ostradiol-Valerianat und Ostradiol-Undezylat bei der Frau: Der Verlauf der Konzentrationen von Ostradiol-17beta, Ostron, LH und FSH im serum