[Reactivation by 1-hydroxyimino-4-methyl-2-pentamone of plasma cholinesterases in the dog inhibited by different orgenophosphates].
The hydroxyimino-1 methyl-4 pentanone-2 was selected among several oximes because of its highly successful restoring action on dog plasmatic cholinesterases inhibited by DFP (diisopropyl fluorophosphate). During the in vitro study, this storing action was tested on 10 organophosphates. Results are compared to those obtained when contrathion is used.
D000818:Animals; D002801:Cholinesterase Reactivators / Q000494:pharmacology*; D002802:Cholinesterases / Q000097:blood*; D004285:Dogs; D004789:Enzyme Activation / Q000187:drug effects; D007306:Insecticides / Q000494:pharmacology*; D007531:Isoflurophate / Q000494:pharmacology; D010091:Oximes / Q000494:pharmacology*; D013997:Time Factors
D002801:Cholinesterase Reactivators; D007306:Insecticides; D010091:Oximes; D007531:Isoflurophate; D002802:Cholinesterases
Réactivation par 1'hydroxyimino-1 méthyl-4 pentanone-2 des cholinestérases plasmatiques de chien inhibées par différents organophosphates