A comparison on natriuresis after oral and intravenous sodium loading in sodium-depleted rabbits: evidence for a gastrointestinal or portal monitor of sodium intake.
1. Rabbits in balance on a low sodium diet were given doses of sodium chloride either orally or intravenously. 2. Those receiving oral doses responded with a much greater natriuresis than those receiving intravenous ones. 3. This could be explained by the existence of a sodium input monitor somewhere in the gut or portal circulation.
D000284:Administration, Oral; D000818:Animals; D004064:Digestive System / Q000378:metabolism; D007263:Infusions, Parenteral; D009318:Natriuresis; D011168:Portal System / Q000378:metabolism; D011188:Potassium / Q000652:urine; D011817:Rabbits; D012964:Sodium / Q000378:metabolism*; D012965:Sodium Chloride / Q000008:administration & dosage*
D012965:Sodium Chloride; D012964:Sodium; D011188:Potassium