Cancer mortality in U.S. counties with plastics and related industries.
Counties in the United States have been identified with chemical establishments whose primary manufacturing processes use vinyl chloride. Site-specific cancer mortality comparisons have revealed an excess of multiple myeloma in males associated with two of the manufacturing categories, synthetic rubber and synthetic fibers. A causal relationship between these manufacturing categories and multiple myeloma could not be established. An industry-based assessment of the occupational contribution to this excess is needed to evaluate the etiologic importance of this relationship.
D002482:Cellulose / Q000633:toxicity; D002617:Chemical Industry; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000139:chemically induced; D008175:Lung Neoplasms / Q000139:chemically induced; D008297:Male; D009101:Multiple Myeloma / Q000139:chemically induced; D009369:Neoplasms / Q000139:chemically induced* / Q000401:mortality; D010969:Plastics / Q000633:toxicity*; D012004:Rectal Neoplasms / Q000139:chemically induced; D012408:Rubber / Q000633:toxicity; D013997:Time Factors; D014481:United States; D014752:Vinyl Chloride / Q000633:toxicity*; D014753:Vinyl Compounds / Q000633:toxicity*
D010969:Plastics; D014753:Vinyl Compounds; D002482:Cellulose; D012408:Rubber; D014752:Vinyl Chloride