The management of glottic carcinoma by primary irradiation with surgery in reserve.
Four hundred nineteen cases of carcinoma of the larynx (1962-1965, Christie Hospital) treated primarily by radiation with surgery in reserve for cases where radiation failed, are reviewed. Two hundred ninety-one of these cases were glottic carcinomas and cure rates, and contribution from subsequent surgery is indicated in detail. Finally the overall results are compared with a larger series of 605 cases (1955-1961). Five-year cure rate in early cases is consistent at 89 percent; likewise in the latest cases at 30 percent, the intermediate group appear to have improved by some 8 percent over the period outlined. The overall cure rate is 70 percent.
D002294:Carcinoma, Squamous Cell / Q000145:classification / Q000532:radiotherapy / Q000628:therapy*; D005500:Follow-Up Studies; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000145:classification / Q000532:radiotherapy / Q000628:therapy*; D007825:Laryngectomy; D009364:Neoplasm Recurrence, Local