Inflammatory involvement of vertebrae in ankylosing spondylitis.
Unusual destructive lesions of the cervical and lumbar vertebrae are described in two patients with ankylosing spondylitis. Biopsy of a lesion from one of the patients showed it to be inflammatory in nature. Possible mechanisms for vertebral centrum involvement in ankylosing spondylitis, centering on the role of enthesopathies are discussed.
D002574:Cervical Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D007249:Inflammation / Q000209:etiology / Q000473:pathology; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D011859:Radiography; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000473:pathology