Autonomic dysfunction in botulism B: a clinical report.
Nine cases of botulism B with preponderant effects upon cholinergic autonomic innervation are presented. Blurred vision and dry mouth were constant symptoms. Impairment of salivary and lacrimal secretion were detectable for months. In the absence of clinical signs, electromyographic studies did not reveal neuromuscular involvement. Administration of antitoxin in the late course of such cases is not recommended, but guanidine can be used. Doubt is cast upon a new clinical entity called "acute autonomic neuropathy."
D000328:Adult; D000992:Antitoxins / Q000627:therapeutic use; D001341:Autonomic Nervous System / Q000503:physiopathology*; D001906:Botulism / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology* / Q000628:therapy; D003248:Constipation / Q000209:etiology; D003680:Deglutition Disorders / Q000209:etiology; D004576:Electromyography; D005260:Female; D005506:Food Contamination; D006146:Guanidines / Q000627:therapeutic use; D006801:Humans; D007765:Lacrimal Apparatus / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011950:Receptors, Cholinergic; D012472:Salivation; D013997:Time Factors; D014786:Vision Disorders / Q000209:etiology
D000992:Antitoxins; D006146:Guanidines; D011950:Receptors, Cholinergic