Hypertension, oedema, and suppressed renin aldosterone system due to unsupervised salt administration.
This paper describes an infant with gastroenteritis, who developed hypertension and oedema after administration of inaccurately prepared oral glucose salt solution. The renin aldosterone system was suppressed in this child and it was suggested that this may be a factor in the development of hypernatraemia when abnormal water losses occur in infants fed on hyperosmolar feeds. Unless salt can be given accurately in small amounts it may be safer to advise feeds of glucose only in infants with mild diarrhoea.
D000450:Aldosterone / Q000097:blood; D002675:Child, Preschool; D003968:Diarrhea, Infantile / Q000178:diet therapy; D004487:Edema / Q000139:chemically induced*; D005260:Female; D005947:Glucose; D006801:Humans; D006955:Hypernatremia / Q000209:etiology; D006973:Hypertension / Q000139:chemically induced*; D012083:Renin / Q000097:blood; D012462:Saline Solution, Hypertonic / Q000009:adverse effects*; D012965:Sodium Chloride / Q000009:adverse effects*
D012462:Saline Solution, Hypertonic; D012965:Sodium Chloride; D000450:Aldosterone; D012083:Renin; D005947:Glucose