Nitroblue tetrazolium test in patients with sickle-cell anemia.
Forty-four patients who had sickle-cell anemia were examined to evaluate the reliability and usefulness of the nitroblue tetrazolium (NBT) test. The patients with sickle-cell anemia in painful crisis with bacterial infection often had low percentages of NBT reduction or negative results. The NBT test did not differentiate well between sickle-cell anemia with bacterial infection and without bacterial infection.
D000328:Adult; D000755:Anemia, Sickle Cell / Q000097:blood / Q000150:complications*; D001424:Bacterial Infections / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007958:Leukocyte Count; D008875:Middle Aged; D009580:Nitroblue Tetrazolium; D013778:Tetrazolium Salts
D013778:Tetrazolium Salts; D009580:Nitroblue Tetrazolium