Integration of pulsatile gonadotropin secretion by timed urinary measurements: an accurate and sensitive 3-hour test.
The integration of pulsatile gonadotropin secretion by the radioimmunoassay of an acetone precipitation from a short-term urine sample was evaluated. FSH and LH excretion over a 3-h period was compared to the mean level of 10 blood samples obtained every 20 min for a similar time period from 71 patients. A highly significant correlation existed between blood and urine results. In addition, the gonadotropin levels obtained from a 3-h sample correlated well with the 24 h excretion of FSH and LH from the same individual. A 3-h urine collection can provide a simple, sensititve, and accurate means of assessing circulating FSH and LH levels.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000856:Anorexia Nervosa / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood / Q000378:metabolism* / Q000652:urine; D006801:Humans; D007223:Infant; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism* / Q000652:urine; D008593:Menopause; D008722:Methods; D008875:Middle Aged; D011863:Radioimmunoassay; D013997:Time Factors
D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone