Influence of bovine somatotropin on the liver experimentally damaged with carbon tetrachloride.
The influence of bovine somatotropin in acute CCl4 poisoning was studied in rabbits. Somatotropin was injected subcutaneously in doses of 2.5 mg/kg. Liver damage was assessed on the basis of alanine and aspartate aminotransferase and aldolase activities. STH injected during 10 experimental days or 5 days preceding experimental poisoning with CCl4 did not increase the degree of liver damage in comparison with the group of animals injected only with carbon tetrachloride.
D000410:Alanine Transaminase / Q000032:analysis*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000032:analysis*; D002252:Carbon Tetrachloride Poisoning / Q000378:metabolism*; D005634:Fructose-Bisphosphate Aldolase / Q000032:analysis*; D013006:Growth Hormone / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D011817:Rabbits
D013006:Growth Hormone; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D005634:Fructose-Bisphosphate Aldolase