The criterion of the inhalation test to allergens at establishing specific hyposensitizing in allergic asthma.
The experience we had in our casuistics as regards 1,000 asthmatics, demonstrates the positive inhalation test (IT) to allergens, only in about 40% of the asthmatics having positive cutaneous test (CT). The technic for determination has used the FEV1 criterion. We correlated the data of the anamnesis (A), CT and IT. The indications of allergenic etiology concerning A, have been divided into three categories: certain anamnesis (CA), suggestive anamnesis (SA) and unconclusive anamnesis (UA). At asthmatics having + CT, CA was associated to + IT in 92%, to SA in 49% and to UA in 11% of the cases. At asthmatics having --CT, CA is possibly associated to + IT, much more rarely associated to SA and not at all associated to UA. From these correlations we deduce the value of A and the fact that --IT is sometimes a false negative test. It further results that IT is not absolutely necessary in cases having CA and + CT. However, IT becomes useful in cases having CA/SA and --CT, as well as in cases having SA/UA and +CT. In 611 persons having allergic asthma lasting cures (1-6 years) of SH have been obtained successfuly in 92% and unsuccessfuly in 8% of the cases. From this total, lot 1 (437 cases) has been selected according to criterion CA/SA and +CT; lot II (130 cases) has associated in addition to criterion of selection by +IT; lot III (44 Cases) was selected with CA/SA, +CT and --IT. Although the selection has been different, the SH results have been identical. From this we infer the spheres of SH efficacy exceed the limit of every selection criterion mentioned before. Further it is to be inferred that the routine IT brings a satisfactory selection for the SH decision only in the mentioned conditions.
D000485:Allergens; D001249:Asthma / Q000175:diagnosis* / Q000276:immunology; D003888:Desensitization, Immunologic; D006967:Hypersensitivity / Q000175:diagnosis* / Q000276:immunology; D012882:Skin Tests
D000485:Allergens