Localization of the beta chain of human chorionic gonadotropin on human tumor cells and placental cells.
With the use of peroxidase-labeled antibody to the beta chain of human chorionic gonadotropin, sections of ten human malignant tumors were found to react with this antibody. It is postulated that both selective host immunosuppression by tumors and selective maternal immunosuppression by fetal tissues may be mediated by human chorionic gonadotropin.
D000818:Animals; D002642:Chick Embryo; D006063:Chorionic Gonadotropin / Q000378:metabolism*; D046508:Culture Techniques; D006801:Humans; D009369:Neoplasms / Q000378:metabolism*; D010920:Placenta / Q000378:metabolism*; D011817:Rabbits / Q000276:immunology
D006063:Chorionic Gonadotropin