[Effect of tranquilizers and analgesics on the permeability of the histohematic barriers for sulfacyl in inflammation].
The effect of neurotropics (analgetics and tranquilizers) on the permeability of histo-blood barriers in normalcy and pathology was wound to be dissimilar. In tests conducted on intact rats the studied neurotropic agents used in pharmacological doses did not affect the permeability of the histological-blood barriers of the brain and spleen with respect to the indicator--sodium sulfacyl. In rats with an inflammation focus the same drugs produced changes of the said factor, not always similar in their orientation (rise of fall).
D000632:Aminopyrine / Q000494:pharmacology; D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D001561:Benzilates / Q000494:pharmacology; D001812:Blood-Brain Barrier / Q000187:drug effects; D002328:Carisoprodol / Q000494:pharmacology; D002463:Cell Membrane Permeability / Q000187:drug effects*; D002707:Chlordiazepoxide / Q000494:pharmacology; D003975:Diazepam / Q000494:pharmacology; D007249:Inflammation / Q000503:physiopathology*; D008620:Meprobamate / Q000494:pharmacology; D009020:Morphine / Q000494:pharmacology; D009025:Morpholines / Q000494:pharmacology; D051381:Rats; D013154:Spleen / Q000187:drug effects; D013409:Sulfacetamide / Q000032:analysis / Q000494:pharmacology*; D013997:Time Factors; D014149:Tranquilizing Agents / Q000494:pharmacology*
D000700:Analgesics; D001561:Benzilates; D009025:Morpholines; D014149:Tranquilizing Agents; D000632:Aminopyrine; D002328:Carisoprodol; D013409:Sulfacetamide; D002707:Chlordiazepoxide; D009020:Morphine; D008620:Meprobamate; D003975:Diazepam
Vliianie trankvilizatorov i anal'getikov na pronitsaemost' gisto-gematicheskikh bar'erov dlia sul'fatsila v usloviiakh vospaleniia