Antispermatogenic activity of 1-p-chlorobenzyl-1H-indazol-3-carboxylic acid (AF 1312/TS) in rats. I. Trials of single and short-term administrations with study of pharmacologic and toxicologic effects.
D000367:Age Factors; D000818:Animals; D000988:Antispermatogenic Agents / Q000008:administration & dosage / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D005260:Female; D007191:Indazoles / Q000008:administration & dosage / Q000633:toxicity*; D007928:Lethal Dose 50; D008297:Male; D009929:Organ Size / Q000187:drug effects; D011720:Pyrazoles / Q000633:toxicity*; D051381:Rats; D012039:Regional Blood Flow / Q000187:drug effects; D012670:Seminiferous Epithelium / Q000187:drug effects; D012671:Seminiferous Tubules / Q000187:drug effects; D012708:Sertoli Cells / Q000187:drug effects; D013087:Spermatids / Q000187:drug effects; D013090:Spermatocytes / Q000187:drug effects; D013093:Spermatogonia / Q000187:drug effects; D013737:Testis / Q000098:blood supply / Q000187:drug effects
D000988:Antispermatogenic Agents; D007191:Indazoles; D011720:Pyrazoles