The influence of a new benzonaphtyridone derivative (IFC-45) with antidepressant activity on the central nervous system. Part II. The influence on the amphetamine and reserpine effects and other pharmacological studies.
The Influence of a New Benzonaphtyridone Derivative (IFC-45) with Antidepressant Activity on the Central Nervous System. Part II: The Influence on the Amphetamine and Reserpine Effects and Other Pharmacological Studies. Pol. J. Pharmacol, Pharm. 1975, 27, 479--491. IFC-45 (chem. formula see p. I, page 471) potentiated amphetamine action in a similar manner as standard drugs, had significant but slightly less than the compared standards anti-reserpine activity. IFC-45 did not act anticonvulsivantly, did not affect physostigmine toxicity or evipan anaesthesia.
D000639:Amitriptyline / Q000494:pharmacology; D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D001831:Body Temperature; D001921:Brain / Q000187:drug effects*; D004357:Drug Synergism; D007099:Imipramine / Q000494:pharmacology; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D009287:Naphthyridines / Q000494:pharmacology*; D051381:Rats; D012110:Reserpine / Q000037:antagonists & inhibitors*
D009287:Naphthyridines; D000639:Amitriptyline; D012110:Reserpine; D000661:Amphetamine; D007099:Imipramine