Metabolism of monofluorobenzoates by Acinetobacter calcoaceticus N.C.I.B. 8250. Formation of monofluorocatechols.
None of the monofluorobenzoates serves as sole source of carbon and energy for growth of Acinetobacter calcoaceticus but all can contribute to growth on other substrates. The monofluorobenzoates are oxidised by bacteria pre-induced for benzoate oxidation and can themselves induce the appropriate enzymes. The initial products of oxidation have been separated and identified by gas-liquid chromatography. 2-Flurobenzoate is oxidised to catechol, fluoride and 3-fluorocatechol; 3-fluorobenzoate gives 3- and 4-fluorocatechol; 4-fluorobenzoate gives 4-fluorocatechol. The fluorocatechols appear to be partially oxidised beyond the stage of 3-oxoadipate by suitably pre-induced bacteria.
D000150:Acinetobacter / Q000187:drug effects / Q000378:metabolism*; D001565:Benzoates / Q000378:metabolism* / Q000494:pharmacology; D002396:Catechols / Q000378:metabolism*; D002455:Cell Division / Q000187:drug effects; D007700:Kinetics; D010101:Oxygen Consumption; D013386:Succinates / Q000494:pharmacology
D001565:Benzoates; D002396:Catechols; D013386:Succinates