Hormonal regulation of thermogenesis in goslings. Possible role of the thyroid gland.
The experiments performed on 90 male goslings showed that 6 h cold exposure (5 +/- 1 degree C) of the specimens 3, 10 and 21-day-old increases considerably 131I uptake by their thyroid gland. After single subcutaneous injection of thyroxine (100 mug/kg) no significant alterations of the metabolic rate, during 4 h measurements, in comparison with the pre-injection value were observed. Since, in control birds about 17% decrease of the metabolic rate within the same time occurred, as the effect of fasting, it was concluded that thyroxine does have the calorigenic effect. The metabolic rate of the goslings 5 to 7-day-old treated with thyroxine for four consecutive days (100 mug/kg daily) and the control ones was very similar. In the older goslings (22--24 days) thyroxine treatment significantly elevated the metabolic rate. Direct (extrathyroid) effect of TSH on heat production, did not occur in goslings.
D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D001831:Body Temperature / Q000187:drug effects; D003080:Cold Temperature; D004781:Environmental Exposure; D005777:Geese / Q000502:physiology*; D006358:Hot Temperature; D007279:Injections, Subcutaneous; D007457:Iodine Radioisotopes; D008297:Male; D013961:Thyroid Gland / Q000378:metabolism / Q000502:physiology*; D013974:Thyroxine / Q000008:administration & dosage / Q000494:pharmacology; D013997:Time Factors
D007457:Iodine Radioisotopes; D013974:Thyroxine