[Obstetric prognosis in cases of conjugal sterility evaluation and management of 224 couples].
A retrospective study was carried out in 224 sterile couples examined at the Obstetric and Gynecological Clinic of Genoa University for diagnosis and treatment. The study was performed between November 1, 1970 and May 31, 1973. Secondary sterility was not included. Altogether 84 pregnancies were obtained which amounts to a success rate of 37.5%. Of these 84 pregnancies, 15 started after hysterosalpingography and 17 occurred in couples who had not been given any treatment. Gonadotropin therapy yielded good results in cases treated for anovulation (30% pregnancies) and for slight oligoasthenospermia (32.65% pregnancies). Clomiphene treatment, too, gave good results, with 50% pregnancies. In sterility probably due to inflammatory conditions, the success rate obtained by medical treatment with 12%, while surgical management of tubal occlusions, performed in six cases, yielded only one pregnancy; a single pregnancy was equally obtained in three cases of uterine malformation submitted to Strassmann's operation. Also, only one pregnancy followed surgical treatment of the male partner (ligature of the left internal spermatic vein) in three cases of oligoasthenospermia. Among the couples where deficiencies could be ascertained in both partners, 33.33% of the women became pregnant. As for the evolution of the pregnancies obtained, only 9.52% aborted and 2.39% were ectopic.
D000293:Adolescent; D000328:Adult; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D002996:Clomiphene / Q000627:therapeutic use; D005260:Female; D005831:Genital Diseases, Female / Q000150:complications; D006801:Humans; D007047:Hysterosalpingography; D007247:Infertility, Female / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D007248:Infertility, Male / Q000188:drug therapy* / Q000209:etiology; D007558:Italy; D008297:Male; D011247:Pregnancy; D012189:Retrospective Studies; D013081:Sperm Motility; D013091:Spermatogenesis
D006063:Chorionic Gonadotropin; D002996:Clomiphene