Vitamin B6 levels in rheumatoid arthritis: effect of treatment.
Patients with rheumatoid arthritis were found to have low plasma pyridoxal phosphate. Treatment with 50-150 mg/day of pyridoxine hydrochloride for 3 months caused a rise in pyridoxal phosphate in most cases to more than 3 times pretreatment levels. There was, however, no improvement in the clinical aspects of rheumatoid arthritis.
D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000097:blood* / Q000188:drug therapy; D001799:Blood Sedimentation; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011732:Pyridoxal Phosphate / Q000097:blood*; D011736:Pyridoxine / Q000627:therapeutic use*; D012217:Rheumatoid Factor / Q000378:metabolism
D011732:Pyridoxal Phosphate; D012217:Rheumatoid Factor; D011736:Pyridoxine