Effect of long-term chemical sympathectomy on function of canine urinary tract.
Destruction of the adrenergic terminals in the ureter, bladder, and urethra was produced and maintained in 4 dogs for periods up to twelve months by biweekly intraperitoneal injections of 6-hydroxydopamine. The effects on urine transport, storage, and elimination were studied. The results are discussed in the light of current knowledge regarding the sympathetic innervation of these organs and its function.
D000818:Animals; D001692:Biological Transport; D004285:Dogs; D005260:Female; D006892:Hydroxydopamines / Q000494:pharmacology*; D008297:Male; D011941:Receptors, Adrenergic; D014513:Ureter / Q000294:innervation / Q000502:physiology; D014521:Urethra / Q000294:innervation / Q000502:physiology; D001743:Urinary Bladder / Q000294:innervation / Q000502:physiology; D014553:Urinary Tract Physiological Phenomena
D006892:Hydroxydopamines; D011941:Receptors, Adrenergic