Relief of sever left ventricular outflow obstruction in a case of hypertrophic obstructive cardiomyopathy treated with practolol.
The clinical and haemodynamic findings in a patient with hypertrophic obstructive cardiomyopathy and severe left ventricular outflow obstruction are presented. Treatment with an increasing dose of orally administered practolol up to a maximum of 1200 mg a day, resulted in symptomatic improvement, and abolition of the resting gradient when the patient was recatheterized six months later.
D000284:Administration, Oral; D001794:Blood Pressure; D002302:Cardiac Output; D002312:Cardiomyopathy, Hypertrophic / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006339:Heart Rate; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D007601:Jugular Veins / Q000502:physiology; D008875:Middle Aged; D011217:Practolol / Q000008:administration & dosage / Q000627:therapeutic use*; D011674:Pulse; D014690:Venous Pressure
D011217:Practolol