Glycerol: major contributor to the short term protein sparing effect of fat emulsions in normal man.
Intravenous fat emulsions have been advocated as acceptable alternatives to hyperosmolar glucose solutions in parenteral nutrition. The ability of a fat emulsion (soy bean oil suspended in glycerol) to produce nitrogen sparing in the absence of nitrogen intake was examined in normal man. The protein conservation obtained by the fat emulsion can be duplicated by the infusion of glycerol alone in the same amount as that available from the fat emulsion.
D004040:Dietary Carbohydrates / Q000378:metabolism; D004041:Dietary Fats / Q000378:metabolism; D004573:Electrolytes / Q000378:metabolism; D004655:Emulsions; D005223:Fats / Q000378:metabolism / Q000494:pharmacology*; D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D005990:Glycerol / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D007328:Insulin / Q000378:metabolism; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*; D014280:Triglycerides / Q000378:metabolism
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004573:Electrolytes; D004655:Emulsions; D005223:Fats; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D011506:Proteins; D014280:Triglycerides; D009584:Nitrogen; D005990:Glycerol