Steroid metabolism in Bombyx mori, I. Catabolism of ponasterone A and ecdysterone in Bombyx mori.
Ponasterone A, when injected into silkworm larvae (Bombyx mori), was hydroxylated at C-25 and C-26 with the formation of ecdysterone and inokosterone, followed by fission at C-20:C-22 to form poststerone. The catabolism of ecdysterone to poststerone was also clarified. These conversions are thought to constitute part of the detoxication mechanism for exogenous ecdysones in the insect.
D000818:Animals; D012831:Bombyx / Q000378:metabolism*; D002782:Cholestenes / Q000378:metabolism*; D002784:Cholesterol / Q000378:metabolism; D002852:Chromatography, Ion Exchange; D004441:Ecdysterone / Q000378:metabolism* / Q000031:analogs & derivatives; D007447:Invertebrate Hormones / Q000378:metabolism*; D007814:Larva; D010944:Plants / Q000378:metabolism; D013261:Sterols / Q000378:metabolism*
D002782:Cholestenes; D007447:Invertebrate Hormones; D013261:Sterols; D004441:Ecdysterone; C008999:ponasterone A; D002784:Cholesterol