Low oestriol excretion: incidence, significance and treatment in an obstetric population.
In a series of 6,361 consecutive patients, low oestroil excretion late in pregnancy was detected in 871 cases (13-6%) and was associated with significantly increased incidences of still birth (P less than 0-001), neonatal death (P less than 0-001) and intrauterine growth retardation (P less than 0-001). Persistently low oestriol excretion occurred in approximately 3% of patients and two-thirds of these were suitable for conservative treatment with intravenous infusion of dextrose (25%) and fructose (20%) (2 1. of each in 48 hours). In 97 of 147 patients (65%), low oestriol excretion was favourably affected by this regimen, with significantly improved perinatal results (P less than 0-001).
D000596:Amino Acids / Q000627:therapeutic use; D001724:Birth Weight; D002585:Cesarean Section; D004964:Estriol / Q000652:urine*; D005260:Female; D005313:Fetal Death / Q000652:urine; D005315:Fetal Diseases / Q000188:drug therapy / Q000652:urine*; D005865:Gestational Age; D005950:Glucose Solution, Hypertonic / Q000627:therapeutic use; D006801:Humans; D007226:Infant Mortality; D011247:Pregnancy; D011248:Pregnancy Complications / Q000652:urine; D011295:Prenatal Care
D000596:Amino Acids; D005950:Glucose Solution, Hypertonic; D004964:Estriol