Isolation and partial characterization of toxins from the dinoflagellate Gymnodinium breve Davis.
Three neurotoxins were isolated from unialgal cultures of the dinoflagellate Gymnodinium breve Davis. Of the three toxins, only one toxin (T1) has hemolytic acitivity. The major toxin (T2), in chromatographically pure form, appears to have a molecular weight of 725. The neurotoxin T2 has no antiacetylcholinesterase activity.
D000818:Animals; D002800:Cholinesterase Inhibitors; D002845:Chromatography; D002855:Chromatography, Thin Layer; D004141:Dinoflagellida; D056890:Eukaryota; D006461:Hemolysis / Q000187:drug effects; D006868:Hydrolysis; D066298:In Vitro Techniques; D051379:Mice; D010758:Phosphorus / Q000032:analysis; D011817:Rabbits; D013055:Spectrophotometry, Infrared; D014118:Toxins, Biological / Q000032:analysis* / Q000494:pharmacology / Q000633:toxicity
D002800:Cholinesterase Inhibitors; D014118:Toxins, Biological; D010758:Phosphorus