Congenital bronchiolitis obliterans.
A case is described of intrauterine pneumonia with "Congenital Bronchiolitis Obliterans" in a premature infant who died 35 hours after delivery. The patient presented from birth with increasingly severe respiratory insufficiency. Post-mortem histological examination of the lung revealed obliterative bronchiolitis, a rare disease which the patient most probably developed in utero. Only two other similar cases of congenital obliterative bronchiolitis have been reported in the literature, both with obscure etiology. A detailed pathological description of pulmonary changes is given and the literature is reviewed.
D001980:Bronchi / Q000473:pathology; D001991:Bronchitis / Q000151:congenital* / Q000473:pathology; D006097:Granulation Tissue; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000473:pathology*; D008168:Lung / Q000473:pathology; D011014:Pneumonia / Q000151:congenital / Q000473:pathology; D011650:Pulmonary Alveoli / Q000473:pathology