Immobilization error: some theoretical considerations.
The consequences of immobilization error are explored through a model involving the tumor dose-response characteristics. The quantitative effect of such an error depends upon the field size, the shape of the dose-response function, and the position of the nominal dose being delivered on the dose-response function. Squamous-cell carcinoma of the supraglottis and Hodgkin's disease are discussed and values are calculated for the change in tumor control probability which might accompany immobilization error.
D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D004307:Dose-Response Relationship, Radiation; D006689:Hodgkin Disease / Q000532:radiotherapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy; D008962:Models, Theoretical; D011878:Radiotherapy / Q000379:methods*