Preliminary studies on the application of enzyme immunoassay in the detection of antibodies in onchocerciasis.
Preliminary enzyme-linked immunosorbent assay (ELISA) with serum from a patient with onchoceriasis revealed extensive cross-reactions with various nematode antigens. Further tests on a batch of sera from people with proven O. volvulus infections using O. gutturosa antigen, showed that almost all the sera gave higher ELISA values than did control African sera.
D000042:Absorption; D000469:Alkaline Phosphatase; D000906:Antibodies / Q000032:analysis; D003429:Cross Reactions; D006801:Humans; D009855:Onchocerciasis / Q000175:diagnosis*; D011233:Precipitin Tests; D012698:Serologic Tests / Q000379:methods
D000906:Antibodies; D000469:Alkaline Phosphatase