Changes in the phases of left ventricular contraction during induction of general anaesthesia.
By means of polycardiographic tracings the authors assessed the effects of althesin, ketamine and fentanyl on the dynamics of left ventricular contraction when these agents were applied for induction of anaesthesia. A depressing action of althesin was found while fentanyl and ketamine were without effect on the dynamics of left ventricular contraction. Polycardiographic tracings are a useful method for the assessment of the action of pharmacological agents on the cardiovascular system during operations.
D000328:Adult; D000530:Alfaxalone Alfadolone Mixture / Q000494:pharmacology; D000768:Anesthesia, General; D003864:Depression, Chemical; D005283:Fentanyl / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D006352:Heart Ventricles / Q000187:drug effects*; D006801:Humans; D007649:Ketamine / Q000494:pharmacology; D009200:Myocardial Contraction / Q000187:drug effects*; D010701:Phonocardiography
D007649:Ketamine; D000530:Alfaxalone Alfadolone Mixture; D005283:Fentanyl