[The morphology of the CNS in carbon tetrachloride poisoning. 6. Histology of spinal ganglia in the lumbosacric region (experimental studies) (author's transl)].
As a further report on our investigations concerning the effects of carbon tetrachloride intoxication the histological findings in lumbosacric ganglia of 48 rabbits are presented. The substance was applied perorally as well as a subcutaneously to 24 animals in each group. Detectable alterations were weak and consisted of pathobioses and pathonecroses of the ganglion cells and, partly as a consequence of these lesions, of an activation of glial elements. In most of the test animals as well as in 10 of the 11 controls cytoplasmic vascuoles were found. From the pathogenetic point of view the impairment of elementary cell functions by anoxemia both with primary and secondary hepatorenally caused lesions may be of major importance.
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000473:pathology*; D005727:Ganglia, Spinal / Q000473:pathology*; D009336:Necrosis; D009457:Neuroglia / Q000473:pathology; D009474:Neurons / Q000473:pathology; D011817:Rabbits; D013997:Time Factors
Die Pathomorphologie des ZNS bei der Tetrachlorkohlenstoff-intoxikation. 6. Die Pathohistologie lumbosakraler Spinalganglien im Tierexperiment