[Changes in bone turnover under immobilization and remobilization. Animal experiments using 45Ca and tetracycline labelling (author's transl)].
This paper presents an experimental study of rabbits immobilized in plaster of paris casts. By means of Tetracycline and 45Ca-labelling an immobilisation over 12 weeks showed a significant diminuition of bone formation. In the first stages of remobilisation the bone formation was found to be increased and became normally in a later stage. The lower dorsal spine was not sufficiently immobilized in our experiments. Therefore significant changes of bone turnover could not be observed.
D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D002132:Calcium Radioisotopes; D002133:Calcium Sulfate; D005269:Femur / Q000378:metabolism; D007103:Immobilization; D010024:Osteoporosis / Q000209:etiology; D011817:Rabbits; D013752:Tetracycline / Q000378:metabolism; D013904:Thoracic Vertebrae / Q000378:metabolism; D013997:Time Factors
D002132:Calcium Radioisotopes; D013752:Tetracycline; D002133:Calcium Sulfate
Die Veränderungen des Knochenanbaus unter Immobilisation und Remobilisation. Tierexperimentelle Untersuchungen am Kaninchen unter Verwendung von 45Ca und Tetracyclinmarkierung