Distribution of the modified nucleoside Q and its derivatives in animal and plant transfer RNA's.
The modified nucleoside, 7-(4,5-cis-dihydroxy-1-cyclopenten-3-yl-aminomethyl)-7-deazaguanosine, designated as Q, and its derivative, Q*, were found in tRNA's from various organisms, including several mammalian tissues, other animals such as starfish, lingula and hagfish, and wheat germ. Q isolated from rat liver tRNA was found to be identical with E. coli Q by mass spectrometry and thin-layer chromatography. Thus the rare modified nucleoside Q originally isolated from E. coli tRNA, is widely distributed in various organisms. Analysis of the mass spectrum of Q* suggested that it has a different side chain from Q.
D000818:Animals; D002855:Chromatography, Thin Layer; D006151:Guanosine / Q000031:analogs & derivatives* / Q000032:analysis; D008099:Liver / Q000032:analysis; D013058:Mass Spectrometry; D009928:Organ Specificity; D012343:RNA, Transfer / Q000032:analysis*; D051381:Rats; D013045:Species Specificity
D006151:Guanosine; D012343:RNA, Transfer