2-(3,4-Dichloroanilino)quinolizinium bromide, a unique antispasmodic, antisecretory, and antiulcerogenic agent.
2-(3,4-Dichloroanilino)quinolizinium bromide (3) was prepared by reaction of 2-bromoquinolizinium bromide with 3,4-dichloroaniline in ethanol. This compound possesses unique antispasmodic, antisecretory, and antiulcerogenic properties.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D003106:Colon / Q000187:drug effects; D003864:Depression, Chemical; D004285:Dogs; D005750:Gastric Juice / Q000378:metabolism; D005765:Gastrointestinal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D008026:Ligation; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010208:Papaverine / Q000494:pharmacology; D010276:Parasympatholytics / Q000138:chemical synthesis* / Q000494:pharmacology; D011708:Pylorus / Q000502:physiology; D000644:Quaternary Ammonium Compounds / Q000138:chemical synthesis / Q000494:pharmacology; D011807:Quinolizines / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats
D005765:Gastrointestinal Agents; D010276:Parasympatholytics; D000644:Quaternary Ammonium Compounds; D011807:Quinolizines; C010917:diclonium bromide; D001285:Atropine; D010208:Papaverine