Suprasellar disturbance in the syndrome of fertile eunuchoidism: case report.
A case of fertile eunuchoidism is presented. The diagnosis was established on the basis of low androgen secretion in the presence of active spermatogenesis, increase in testosterone output after gonadotrophin stimulation, and adequate peripheral response to exogenous testosterone. Resistance to clomiphene stimulation but normal pituitary response to LH-RH was elicited indicating a suprasellar disturbance as the cause of the disorder.
D000328:Adult; D000728:Androgens / Q000097:blood; D001921:Brain / Q000503:physiopathology*; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D002996:Clomiphene / Q000494:pharmacology; D005058:Eunuchism / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D005298:Fertility; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007985:Leydig Cells; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D013081:Sperm Motility; D013091:Spermatogenesis; D013268:Stimulation, Chemical; D013737:Testis / Q000473:pathology
D000728:Androgens; D006063:Chorionic Gonadotropin; D002996:Clomiphene; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone