Evaluation of an anti-infective combination. Trimethoprim-sulfamethoxazole (Bactrim, Septra).
Trimethoprim and sulfamethoxazole, combined in a synthetic anti-infective preparation, act  synergistically to inhibit the growth of certain microorganisms. This  combination is effective orally in acute and chronic urinary tract infections. It also has been used successfully to treat other infectious conditions, including bacterial upper respiratory tract infections, ear infections, skin and soft-tissue infections, septicemias, acute and subacute bacterial endocarditis, enteric fever, brucellosis, prostatitis, and gonorrhea. It is well tolerated by most patients.
D000208:Acute Disease; D000284:Administration, Oral; D000328:Adult; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy*; D002006:Brucellosis / Q000188:drug therapy; D002648:Child; D002908:Chronic Disease; D004338:Drug Combinations; D004698:Endocarditis, Subacute Bacterial / Q000188:drug therapy; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy; D006801:Humans; D008297:Male; D011247:Pregnancy; D011472:Prostatitis / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000188:drug therapy; D018805:Sepsis / Q000188:drug therapy; D012874:Skin Diseases, Infectious / Q000188:drug therapy; D013420:Sulfamethoxazole / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D013607:Tablets; D014295:Trimethoprim / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D014552:Urinary Tract Infections / Q000188:drug therapy
D004338:Drug Combinations; D013607:Tablets; D014295:Trimethoprim; D013420:Sulfamethoxazole