Air-rinsing after dialysis. A mode of transmission of hepatitis virus.
During a recent outbreak of hepatitis B among patients receiving dialysis, georgraphic and temporal distribution of cases in the absence of exposure to blood products suggested patient-to-patient transmission. The patients who contracted hepatitis used Kiil dialyzers with a single-pass dialysate system, while patients who used hollow-fiber dialyzers appeared to be protected. Blood was returned to patients after Kiil dialysis by the air-rinse technique with the use of a nonsterile plastic tube attached to a manometer bulb. Laboratory experiments demonstrated that Staphylococcus aureus and poliovirus became widely distributed throughout the Kiil dialyzer when introduced during the rinse phase by contaminating the air-rinse tubing.
D000391:Air Microbiology; D003428:Cross Infection / Q000635:transmission; D004196:Disease Outbreaks / Q000453:epidemiology; D006509:Hepatitis B / Q000453:epidemiology / Q000635:transmission*; D006511:Hepatitis B Antigens / Q000302:isolation & purification; D006801:Humans; D007688:Kidneys, Artificial; D008111:Liver Function Tests; D010564:Personnel, Hospital; D006435:Renal Dialysis / Q000009:adverse effects*; D013210:Staphylococcus / Q000302:isolation & purification; D013997:Time Factors
D006511:Hepatitis B Antigens