A basis for the difference in toxicity of methotrexate, aminopterin and methasquin in mice.
D000630:Aminopterin / Q000378:metabolism / Q000633:toxicity*; D000818:Animals; D000970:Antineoplastic Agents / Q000378:metabolism / Q000633:toxicity*; D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000633:toxicity*; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000378:metabolism; D007700:Kinetics; D007928:Lethal Dose 50; D008297:Male; D008727:Methotrexate / Q000378:metabolism / Q000633:toxicity*; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D013329:Structure-Activity Relationship
D000970:Antineoplastic Agents; D001224:Aspartic Acid; D000630:Aminopterin; D008727:Methotrexate