Idiopathic heart block: association with vitiligo, thyroid disease, pernicious anaemia, and diabetes mellitus.
Out of 100 patients with chronic heart block 16 had one or more autoimmune disorders-namely, vitiligo (5,) hypothyroidism (4), Graves's disease (1), pernicious anaemia (2), and diabetes mellitus (9). All these disorders occurred with greater frequency than normal and were more prevalent than in a group of hospital inpatients of comparable age. Autoantibodies were not increased. We suggest that among patients with idiopathic heart block there is a subgroup with multiple autoimmune disorders.
D000328:Adult; D000368:Aged; D000752:Anemia, Pernicious / Q000150:complications*; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000150:complications*; D048909:Diabetes Complications; D005260:Female; D006327:Heart Block / Q000150:complications* / Q000276:immunology; D006801:Humans; D006980:Hyperthyroidism / Q000276:immunology; D007037:Hypothyroidism / Q000150:complications; D008297:Male; D008875:Middle Aged; D009928:Organ Specificity; D013959:Thyroid Diseases / Q000150:complications*; D014820:Vitiligo / Q000150:complications*
D001323:Autoantibodies