The in situ localization of folic acid.
A histochemical azo-coupling method for localizing folic acid in situ is described. Cat and rat liver, kidney, bone marrow and brain were found to be rich in folic acid; stomach, intestine, salivary glands, and blood contained less. Folic acid was localized in the cytoplasm of tissues having a very active metabolism, but in the nucleus of highly specialized cells such as neurons.
D000818:Animals; D001853:Bone Marrow / Q000032:analysis; D001842:Bone and Bones / Q000032:analysis; D001923:Brain Chemistry; D002415:Cats; D005492:Folic Acid / Q000032:analysis*; D005753:Gastric Mucosa / Q000032:analysis; D006651:Histocytochemistry; D007413:Intestinal Mucosa / Q000032:analysis; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D008722:Methods; D009928:Organ Specificity; D051381:Rats; D012469:Salivary Glands / Q000032:analysis; D013045:Species Specificity
D005492:Folic Acid