In vitro release of noramidopyrine methansulfonate sodium from suppository as a function of particle size and concentration.
The effect of particle size and percentage concentration of noramidopyrine methansulfonate sodium on its release from Witepsol H 15 suppository base is studied. It is proved that the finer the drug particles the less its release and the more the drug concentration the more its release.
D000632:Aminopyrine / Q000031:analogs & derivatives*; D002626:Chemistry, Pharmaceutical; D004177:Dipyrone; D010232:Paraffin; D010316:Particle Size; D013053:Spectrophotometry; D013488:Suppositories
D013488:Suppositories; D000632:Aminopyrine; D004177:Dipyrone; D010232:Paraffin