Antigenic relationships of group A arboviruses by plaque reduction neutralization testing.
Antigenic relationships of 20 group A arboviruses were assessed by the plaque reduction neutralization test, using highly specific hyperimmune mouse ascitic fluids and antisera. The existence of three complexes of group A viruses was verified. With rare exceptions, heterologous neutralization reactions were observed only among viruses in the same complex; however there were at least one or two immune reagents in each complex which were broadly cross-reactive within that complex.
D000818:Animals; D000910:Antibodies, Heterophile; D000937:Antigen-Antibody Reactions; D001103:Arboviruses / Q000276:immunology*; D001202:Ascitic Fluid / Q000276:immunology; D003429:Cross Reactions; D004812:Epidemiologic Methods; D007106:Immune Sera; D066298:In Vitro Techniques; D009500:Neutralization Tests; D010948:Viral Plaque Assay
D000910:Antibodies, Heterophile; D007106:Immune Sera