Malignant melanoma of the choroid in an 11-month-old infant.
A malignant melanoma of the choroid was observed in an 11-month-old fair-skinned Danish boy - one of the youngest cases ever published. There was no evidence of pre-existing melanosis of eyes or skin. The tumour showed histopathologically a typical "adult" pattern and was classified as a mixed tumour. The melanin content was marked. In some earlier reports on uveal tumours within the first year of life, pigmentation was sparse or lacking; a hypothesis has therefore previously been advanced: That melanomas are unable to produce melanin so early in life. The present case renders proof against this hypothesis.
D000367:Age Factors; D002830:Choroid Neoplasms / Q000473:pathology*; D002924:Ciliary Body / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D008543:Melanins; D008545:Melanoma / Q000473:pathology*; D012168:Retinal Pigments
D008543:Melanins; D012168:Retinal Pigments