[Effect of ectopic transplantations on the cytological structure of mouse rhabdomyosarcomas].
12 mouse rhabdomyosarcomas from V--XI transplant generations were investigated at their growing in the anterior chamber of the eye, in the testis, lungs and subcutaneous fibrous tissue. With these modes of transplantation rhabdomyosarcomas were seen differentiating to different levels and differed in their cell populations. The most differentiated rhabdomyosarcomas were in the anterior chamber of the eye: they formed myotubes with cross-striated myofibrilles; the least differentiated ones occurring in lungs. Rhabdomyosarcomas, inoculated in testes, intensively dessiminated in the lymph-nodes and in the organs of abdomen. It is concluded that the degree of tumor autonomy depends on the tumor--organism interactions.
D000818:Animals; D000867:Anterior Chamber; D002454:Cell Differentiation; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002999:Clone Cells / Q000166:cytology; D005134:Eye Neoplasms / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008748:Methylcholanthrene; D051379:Mice; D008810:Mice, Inbred C57BL; D009368:Neoplasm Transplantation; D012208:Rhabdomyosarcoma / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology; D013736:Testicular Neoplasms / Q000473:pathology
D008748:Methylcholanthrene
Vliianie éktopicheskikh transplantatsiĭ na tsitologicheskuiu strukturu rabdomiosarkom mysheĭ