Artificial induction of lactation in cattle by use of dexamethasone trimethylacetate.
Injections of dexamethasone trimethylacetate initiated lactation in nulliparous Ayrshire heifers previously given a series of injections of oestradiol benzoate plus progesterone to develop mammary glands. Essentially normal lactation occurred following injection of 20 mg/day dexamethasone for 3 days, whereas injection of 40 mg/day for 4 days initiated secretion of smaller volumes of milk-like fluid containing relatively high levels of lipid. Milking alone failed to initiate lactation.
D000818:Animals; D002364:Caseins / Q000032:analysis; D002417:Cattle / Q000502:physiology*; D003907:Dexamethasone / Q000008:administration & dosage / Q000494:pharmacology*; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D007279:Injections, Subcutaneous; D007774:Lactation / Q000187:drug effects*; D007785:Lactose / Q000032:analysis; D008055:Lipids / Q000032:analysis; D008321:Mammary Glands, Animal / Q000187:drug effects; D008892:Milk / Q000032:analysis; D011247:Pregnancy; D011374:Progesterone / Q000494:pharmacology; D013268:Stimulation, Chemical
D002364:Caseins; D008055:Lipids; D011374:Progesterone; D004958:Estradiol; D003907:Dexamethasone; D007785:Lactose