Comparative value of arecoline hydrobromide and bunamidine hydrochloride for the treatment of Echinococcus granulosus in dogs.
A controlled trial involving 122 dogs experimentally infected with Echinococcus granulosus was carried out to compare the efficiency of arecoline hydrobromide and bunamidine hydrochloride. A single treatment with arecoline hydrobromide at a dose rate of 4 mg/kg or with bunamidine hydrochloride at 50 mg/kg gave a similar degree of efficiency against young worms. At these dose rates, worms were still present in almost half the dogs at autopsy.
D000578:Amidines / Q000627:therapeutic use*; D000818:Animals; D001115:Arecoline / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004443:Echinococcosis / Q000188:drug therapy / Q000662:veterinary*; D005260:Female; D008297:Male
D000578:Amidines; D001115:Arecoline