[99MTechnetium-fibrinogen labeling using electrolytic zircuronium release].
An electrolytic method for labelling fibrinogen with zirconium as a reductant for 99mTc is presented. The optimal labelling conditions and the in-vitro screening are subject of the study. First clinical experience indicates that the substance is clottable in vivo and applicable for localization.
D000818:Animals; D001778:Blood Coagulation Disorders / Q000175:diagnosis; D002850:Chromatography, Gel; D002855:Chromatography, Thin Layer; D004572:Electrolysis; D004586:Electrophoresis; D005340:Fibrinogen; D006506:Hepatitis A / Q000635:transmission; D006801:Humans; D066298:In Vitro Techniques; D007553:Isotope Labeling / Q000379:methods*; D010084:Oxidation-Reduction; D011485:Protein Binding; D011817:Rabbits; D051381:Rats; D013667:Technetium; D015040:Zirconium / Q000633:toxicity
D013667:Technetium; D005340:Fibrinogen; D015040:Zirconium
99M-Technetium-Fibrinogenmarkierung mittels elektrolytischer Zirkonfreisetzung