The immune reaction to human breast cancer: a comparison of skin and leucocyte migration tests.
In vivo and in vitro tests of cellular immunity using autologous tumour antigen have been performed in patients after mastectomy for cancer and in a control group with benign tumours of the breast. Overall, the incidence of positive immune reactions in both groups was 45 per cent. Poor correlation was found between the results of in vivo and in vitro tests, which could not be explained in terms of serum factors. The specificity of the reaction is questioned but the clinical relevance will be determined by long term follow-up.
D000368:Aged; D001943:Breast Neoplasms / Q000276:immunology*; D002464:Cell Migration Inhibition; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007962:Leukocytes / Q000276:immunology; D008875:Middle Aged; D012882:Skin Tests