Locomotor and avoidance behavior in rats with partial or total hippocampal perforant paths sections.
Bilateral partial damage to the hippocampal perforant paths in rats produced impaired two-way active avoidance performance, while the behavior in open field, passive and one-way active avoidance remained unchanged. Total disruption of the perforant path projection resulted in increased open field activity and impaired one-way active avoidance, but normal passive avoidance behavior. The results are discussed in terms of reduced sensory information to the hippocampal formation.
D000818:Animals; D004924:Escape Reaction / Q000502:physiology*; D005106:Exploratory Behavior / Q000502:physiology*; D006624:Hippocampus / Q000502:physiology*; D008297:Male; D051381:Rats