Human disease caused by Brucella canis. A clinical and epidemiologic study of two cases.
Nonlaboratory-associated human illness caused by Brucella canis occurred in two persons. Fever, chills, malaise, and weight loss were prominent symptoms in both patients. Epidemiologic investigation identified a household dog as the likely source of one patient's infection, and serologic studies and blood cultures on neighborhood dogs showed that approximately 30% were positive for B canis. Persons exposed to infected dogs appeared to have a low risk of disease. Although routine Brucella agglutinin tests do not detect antibodies to B canis, available methods for diagnosis include a specific B canis serologic test and culture techniques.
D000293:Adolescent; D000328:Adult; D000373:Agglutinins / Q000032:analysis; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D002002:Brucella / Q000276:immunology / Q000302:isolation & purification*; D002006:Brucellosis / Q000276:immunology / Q000635:transmission* / Q000662:veterinary; D004283:Dog Diseases / Q000382:microbiology; D004285:Dogs / Q000382:microbiology*; D006801:Humans; D008297:Male; D015047:Zoonoses
D000373:Agglutinins; D000907:Antibodies, Bacterial