Thioacyl esters of nucleotides: synthesis of 3'(2')-O-thiobenzoyl nucleoside 5'-phosphates.
The synthesis of 3'(2')-O-thiobenzoyl nucleoside 5'-phosphates based on the condensation of N-(thiobenzoyl)-imidazole with nucleside 5'-phosphates was carried out. The UV absorption spectra, CD spectra, PMR spectra and chromatographic and electrophoretic characteristics of synthesized compounds were obtained. By means of PMR it was shown that the 2':3' isomer ratio in water at ambient temperature is about 2:3.
D001565:Benzoates / Q000138:chemical synthesis; D002942:Circular Dichroism; D009682:Magnetic Resonance Spectroscopy; D012265:Ribonucleotides / Q000138:chemical synthesis*; D013056:Spectrophotometry, Ultraviolet; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis
D001565:Benzoates; D012265:Ribonucleotides; D013438:Sulfhydryl Compounds