Malignant melanoma of the choroid as related to coexistent benign nevus.
Ninety-five cases of malignant choroidal melanoma collected during a 15-year period have been studied with special emphasis on histological type, coexistence of benign nevus, and prognosis. Elements of benign nevus were found in 78% of the cases. The data tend to support the hyposis that most cases of malignant choroidal melanoma have their origin in a preexisting benign nevus, and that the tumours undergo a gradual change from a differentiated to a less differentiated type.
D000328:Adult; D000367:Age Factors; D000368:Aged; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009506:Nevus / Q000175:diagnosis / Q000473:pathology*; D011379:Prognosis