Biphasic local reaction to a new insulin (U-100).
The phenomenon of localized insulin reaction is described and illustrated by the report of a case. The patient's unusual response consisted of an "early" and a "late" phase to single-peak and single-component insulins. No definite immunologic mechanism was established on the basis of immunologic studies or from histologic examination of skin biopsies.
D000328:Adult; D004342:Drug Hypersensitivity; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000139:chemically induced; D007328:Insulin / Q000009:adverse effects*; D008297:Male; D013997:Time Factors
D007328:Insulin