Concentration of clindamycin in human bone.
Thirty patients undergoing total hip replacement received clindamycin beginning the day before surgery. Mean clindamycin concentrations during surgery were 7.33 +/- 3.37 mug/ml in serum and 2.63 +/- 1.76 mug/g in bone; mean ratio of bone-serum concentration was 0.40 +/- 0.30.
D000328:Adult; D000368:Aged; D001842:Bone and Bones / Q000032:analysis*; D002981:Clindamycin / Q000032:analysis* / Q000097:blood; D006801:Humans; D008875:Middle Aged
D002981:Clindamycin