Comparison of the response of psoriasis, over a 6-month period, to clobetasol propionate and fluocinolone acetonide ointments.
Twenty-nine patients with bilateral psoriasis were treated with clobetasol propionate ointment on one side of the body and fluocinolone acetonide ointment on the other in a double-blind clinical trial lasting 6 months. With one exception, after the first month of treatment, all patients responded better on the clobetasol propionate treated side. There was a tendency for any relapses to be less rapid and less severe in clobetasol propionate treated lesions. No adverse effects from either steroid were observed.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001623:Betamethasone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002648:Child; D005260:Female; D005446:Fluocinolone Acetonide / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy* / Q000473:pathology; D012008:Recurrence
D005446:Fluocinolone Acetonide; D001623:Betamethasone