Limited form of Wegener granulomatosis. Eye involvement as a major sign.
Bilateral uveitis was the initial manifestation of a limited form of Wegener granulomatosis in a 47-year-old man. Diagnosis was established by biopsy of a pulmonary nodule. Subsequently, evidence of lesions developed in the patient's central and peripheral nervous systems, but renal lesions were absent. Pulmonary lesions regressed on therapy with azathioprine and prednisone. Blindness ultimately resulted from retinal phlebitis, vitreous hemorrhages, and neovascular glaucoma.
D001379:Azathioprine / Q000627:therapeutic use; D001706:Biopsy; D001766:Blindness / Q000209:etiology; D005654:Fundus Oculi; D014890:Granulomatosis with Polyangiitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010689:Phlebitis / Q000209:etiology; D011241:Prednisone / Q000627:therapeutic use; D013902:Radiography, Thoracic; D012166:Retinal Hemorrhage / Q000209:etiology; D012169:Retinal Vein; D014605:Uveitis / Q000209:etiology*; D014822:Vitreous Body
D001379:Azathioprine; D011241:Prednisone