[Effects of Turisynchron and Suisynchron on the thyroid gland in rats during simultaneous administration of TSH].
Thyrotrophin was injected i/p at 2 I.U. daily simultaneously with oral administration of Turisynchron at 100 mg/kg or Suisynchron at 125 mg/kg daily for five days to Wistar rats. The uptake of radio-iodine by the thyroid was reduced, and there were slight changes in thyroid structure. Suisynchron produced a milder inhibition of thyroid regulatory mechanisms than Turisynchron.
D000818:Animals; D005260:Female; D008693:Methallibure / Q000031:analogs & derivatives / Q000494:pharmacology*; D051381:Rats; D013268:Stimulation, Chemical; D013890:Thiourea / Q000031:analogs & derivatives*; D013961:Thyroid Gland / Q000187:drug effects* / Q000378:metabolism; D013972:Thyrotropin / Q000494:pharmacology*
D013972:Thyrotropin; D013890:Thiourea; D008693:Methallibure
Uber den Einfluss von TURISYNCHRON und SUISYNCHRON auf die Rattenschilddrüse bei gleichzeitiger Applikation von TSH