[Bone calcium metabolism following local x-irradiation. XIII. Effect of castration and estrogens on the general response of male rats].
The course of local and general deviations in osseous tissue of locally irradiated male white rats is different in hormonally not influenced and in castrated animals. By castration, both the intensity and the variations of this response are inhibited whereas especially the second osseous tissue shows a great deal more sensitivity. The male sex hormones thus lead to a certain instability and intensity of the defence reactions against local radiation damage which derail more easily than in females.
D000367:Age Factors; D000818:Animals; D001842:Bone and Bones / Q000378:metabolism / Q000528:radiation effects*; D002104:Cadmium; D002118:Calcium / Q000378:metabolism*; D002369:Castration; D004307:Dose-Response Relationship, Radiation; D004958:Estradiol / Q000494:pharmacology; D004967:Estrogens / Q000494:pharmacology / Q000502:physiology*; D005260:Female; D008297:Male; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000378:metabolism*; D051381:Rats; D012737:Sex Factors; D013737:Testis / Q000502:physiology; D013977:Tibia
D004967:Estrogens; D002104:Cadmium; D004958:Estradiol; D002118:Calcium
Untersuchungen zum Knochenkalzimstoffwechsel nach lokaler Röntgenbestrahlung. XIII. Mitteilung: Beeinglussung der Allgemeinreaktion bei männlichen Ratten durch Kastration und Ostrogene