Observations of pressure waves in stomach, jejunal, and colonic loops used to replace the esophagus.
The motility characteristics of the stomach, upper jejunum, and right colon were studied in 25 patients in whom these organs were used to replace the resected esophagus. The pattern of motility in all three replacement organs generally was similar to that recorded in normal individuals by other workers. But the stomach replacement showed a greater percentage of Type 1 waves, and Type II contractions were weaker. Activity in the jejunal replacements was much reduced. A propagated pressure wave was observed on swallowing water in the jejunal replacements. The nature of this wave needs further elucidation. The functional result was good, except in patients with a weak or without an upper esophageal sphincter. Patients experienced no pain during the test and no side effects were observed.
D003106:Colon / Q000502:physiology* / Q000601:surgery; D003679:Deglutition; D004938:Esophageal Neoplasms / Q000601:surgery; D004944:Esophagoplasty / Q000379:methods*; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D007583:Jejunum / Q000502:physiology* / Q000601:surgery; D008297:Male; D008787:Metoclopramide / Q000494:pharmacology; D008875:Middle Aged; D013270:Stomach / Q000502:physiology* / Q000601:surgery; D013562:Sympathectomy; D014628:Vagotomy
D008787:Metoclopramide