Preparation, isolation, and identification of 4-dedimethylamino-11-methoxyanhydrotetracycline.
The reaction of diazomethane with 4-dedimethylaminoanhydrotetracycline produced a number of mono-, di-, and tri- methylated products. The isolation of one monomethylated product (4-dedimethylamino-11-methoxyanhydrotetracycline) and its subsequent identification utilizing mass spectral and NMR data are described.
D013058:Mass Spectrometry; D013754:Tetracyclines / Q000032:analysis / Q000138:chemical synthesis / Q000302:isolation & purification
D013754:Tetracyclines; C011213:4-dedimethylamino-11-methoxyanhydrotetracycline