Cerebral mucormycosis following open head trauma. Case report.
The authors describe a case of human cerebral mucormycosis following open head trauma and craniotomy, and discuss possible roles of steroids and antibiotic therapy in its pathogenesis. They suggest that the common usage of prolonged broad-spectrum chemoprophylaxis in head trauma may require critical review.
D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D001927:Brain Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D002555:Cerebrospinal Fluid / Q000382:microbiology; D002648:Child; D006259:Craniocerebral Trauma / Q000150:complications*; D003399:Craniotomy; D005658:Fungi / Q000302:isolation & purification; D006801:Humans; D008297:Male; D009091:Mucormycosis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D011183:Postoperative Complications; D013256:Steroids / Q000009:adverse effects
D000900:Anti-Bacterial Agents; D013256:Steroids; D000666:Amphotericin B