Placental transmission of thyroid-stimulating immunoglobulins.
Long-acting thyroid stimulator (LATS) and LATS protector (LATS-P) were assayed at or near delivery in serum from 18 pregnant women with a history of past or present thyrotoxicosis. The results suggested that neonatal thyrotoxicosis may be predicted prenatally if maternal serum LATS and LATS-P concentrations near delivery are above certain levels.
D000328:Adult; D005260:Female; D005312:Fetal Blood; D006111:Graves Disease / Q000097:blood; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood*; D007074:Immunoglobulin G / Q000032:analysis / Q000097:blood*; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000097:blood; D008135:Long-Acting Thyroid Stimulator / Q000097:blood*; D008431:Maternal-Fetal Exchange; D011247:Pregnancy
D007074:Immunoglobulin G; D008135:Long-Acting Thyroid Stimulator