Low molecular weight specific proteins in identified molluscan neurons. I. Synthesis and storage.
Low molecular weight specific proteins in phenotypically distinct, identified neurons of Aplysia californica, have been detected using a high resolution acid-urea polyacrylamide gel system, and the molecular weight of these proteins labeled by in vitro incubation in [3H]leucine were determined by two different methods. The relative mobilities of these proteins on the acid-urea gel differed significantly, even though they appeared to co-electrophorese on SDS gelss. These identified neurons, and the specific proteins that they synthesize and store represent excellent model systems for the study of specific protein regulation in neurons.
D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D007930:Leucine / Q000378:metabolism; D008433:Mathematics; D008970:Molecular Weight; D008974:Mollusca / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D009474:Neurons / Q000378:metabolism*
D009419:Nerve Tissue Proteins; D007930:Leucine