A remission of goitrous hypothyroidism during pregnancy.
A 21-yr-old female with a diffuse goiter, hypothyroidism, elevated thyroid autoantibodies, and chronic lymphocytic thyroiditis on needle biopsy, was subsequently nongoitrous and euthyroid with normal antibody titers during pregnancy. Following deliver, the goiter reappeared, autoantibody titers rose and hypothyroidism recurred. Chronic lymphocytic thyroiditis may undergo spontaneous remission during pregnancy.
D000328:Adult; D001323:Autoantibodies / Q000032:analysis; D005260:Female; D006042:Goiter / Q000150:complications*; D006386:Hemagglutination Tests; D006801:Humans; D007037:Hypothyroidism / Q000209:etiology*; D011247:Pregnancy; D011248:Pregnancy Complications; D012075:Remission, Spontaneous; D013961:Thyroid Gland / Q000276:immunology; D013967:Thyroiditis, Autoimmune / Q000150:complications* / Q000276:immunology; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
D001323:Autoantibodies; D013972:Thyrotropin; D013974:Thyroxine