[Urinary excretion of pantothenic acid as a measurement of nutritional requirements].
Several groups of male Wistar-Rats were fed for 15 month with a purified diet containing different amounts of pantothenic acid. The groups received 150, 100, 25 and 0% pantothenic acid of the requirement respectively. A further group was fed without pantothenic acid in the diet but administered with the antagonist omega-methyl-pantothenic acid. The excretion of pantothenic acid in the urine was measured at different times, and a groups specific level of excretion could be established for the different groups. Differences to the controls were highly significant in the test groups after 2-18 weeks. Studies of this type were conducted in order to obtain basic informations for later experiments in human beings.
D000818:Animals; D001835:Body Weight; D004032:Diet; D008297:Male; D009747:Nutritional Physiological Phenomena; D009751:Nutritional Requirements; D010205:Pantothenic Acid / Q000037:antagonists & inhibitors / Q000652:urine*; D051381:Rats; D013997:Time Factors
D010205:Pantothenic Acid
Die Pantothensäureausscheidung im Urin als Bezugsgrösse für den Versorgungszustand