Liver dysfunction and histologic abnormalities in neonatal hypopituitarism.
Pituitary aplasia or hypoplasia occurs in anencephalic and normocephalic infants. Two infants with hypopituitarism are described; in each the diagnosis was made clinically. The infants had frank clinical and histologic evidence of the neonatal hepatitis syndrome. There may be more than a chance relationship between the clinicopathologic findings of neonatal hypopituitarism and hepatitis.
D013006:Growth Hormone / Q000627:therapeutic use; D006505:Hepatitis / Q000175:diagnosis; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007018:Hypopituitarism / Q000151:congenital* / Q000188:drug therapy; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D008099:Liver / Q000473:pathology*; D008107:Liver Diseases / Q000503:physiopathology*; D008297:Male; D013963:Thyroid Hormones / Q000627:therapeutic use
D013963:Thyroid Hormones; D013006:Growth Hormone; D006854:Hydrocortisone