Precursor mRNA from erythroid-enriched bone-marrow cells of the rabbit. Electron microscope investigation of precursor mRNA molecules, molecular weight about 1.7 X 10(7), containing mRNA-like structures at one end.
Precursor mRNA (pre-mRNA) molecules, sedimenting at greater than 45 S, from erythroid-enriched bone marrow cells of the rabbit and hemoglobin mRNA molecules from rabbit reticulocytes were investigated by electron microscopy. Four of 98 measured pre-mRNA molecules had a length between 15 and 17.1 mum. In some of the pre-mRNA molecules a characteristic condensed structure was observed at one end, strikingly resembling the structure of the mRNA molecules.
D000740:Anemia; D000818:Animals; D001853:Bone Marrow; D001854:Bone Marrow Cells; D006454:Hemoglobins; D008854:Microscopy, Electron; D008970:Molecular Weight; D012313:RNA / Q000302:isolation & purification; D012333:RNA, Messenger; D011817:Rabbits; D012156:Reticulocytes
D006454:Hemoglobins; D012333:RNA, Messenger; D012313:RNA