The action of group Bm or CisAB sera on group O red cells in the presence of UDP-D-galactose.
Group B and AB sera, acting on O red cells in the presence of UDP-galactose, each converted them into B active cells, which were agglutinated by anti-B human serum (1:512) at the titer of 128-fold, while group Bm and A-1 Bm sera, converted O red cells similarly incubated into B active cells, which were agglutinated by anti-B human serum (1:512) at the titer of 8- to 16-fold. This indicates that alpha-galactosyltransferase activity in Bm and A-1 Bm sera may be about 1/8-1/16 that in B and AB sera. Group CisAB sera, even after absorption of cold anti-B agglutinins with packed, washed group B red cells, did not convert O red cells in the presence of UDP-galactose in such a way that they might agglutinate against anti-B human serum.
D000017:ABO Blood-Group System; D000818:Animals; D004524:Eels / Q000276:immunology; D004798:Enzymes / Q000097:blood; D004912:Erythrocytes / Q000276:immunology; D005690:Galactose; D006386:Hemagglutination Tests; D006602:Hexosyltransferases / Q000494:pharmacology; D006801:Humans; D007518:Isoantibodies; D014531:Uridine Diphosphate Galactose; D014539:Uridine Diphosphate Sugars
D000017:ABO Blood-Group System; D004798:Enzymes; D007518:Isoantibodies; D014539:Uridine Diphosphate Sugars; D014531:Uridine Diphosphate Galactose; D006602:Hexosyltransferases; D005690:Galactose