Early changes in the number of haemopoietic stem cells in irradiated young rats.
The frequency of exogenous haemopoietic spleen colonies in whole-body irradiated rats, aged 4--5 weeks, was found to be linearly dependent upon the dose of inoculated bone marrow or spleen nucleated cells. The recovery rate of the number of haemopoietic stem cells in rats exposed to 300R assessed on day 12 postirradiation was found to be faster in bone marrow than in spleen.
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D006412:Hematopoietic Stem Cells / Q000528:radiation effects*; D011830:Radiation Effects; D051381:Rats; D013154:Spleen / Q000166:cytology; D013997:Time Factors; D014965:X-Rays