Suppression of ultraviolet light-induced tumor formation by dietary antioxidants.
Dietary antioxidants were effective in reducing the number and severity of ultraviolet light-induced squamous cell carcinomas in skin of hairless mice. This and previous studies suggest that antioxidants may play a role in both inhibition of the primary event(s) involved in ultraviolet light-mediated tumor induction and the subsequent development of precancerous lesions into tumors.
D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000517:prevention & control*; D051379:Mice; D009374:Neoplasms, Experimental / Q000517:prevention & control; D009381:Neoplasms, Radiation-Induced / Q000517:prevention & control*; D012878:Skin Neoplasms / Q000517:prevention & control*; D014466:Ultraviolet Rays
D000975:Antioxidants