[Erythropoietic function of the kidneys under conditions of abnormally high oxygen pressure].
Three to five hours after 5-hour exposure of rabbits to high oxygen pressure (2 ata) the erythropoietin proved to disappear from both the arterial and the venous blood plasma of the kidneys. At the same time the blood plasma from the renal vein began to suppress the mitotic activity of erythroblastic cells in the bone marrow culture. These data testify to the fact that under hyperbaric hyperoxia the kidneys secreted the inhibitor of erythropoiesis. No erythropoiesis inhibitor was revealed 24 hours after the hyperoxia.
D000818:Animals; D001853:Bone Marrow / Q000503:physiopathology; D004900:Erythroblasts; D004920:Erythropoiesis; D004921:Erythropoietin / Q000097:blood; D006931:Hyperbaric Oxygenation / Q000009:adverse effects*; D007668:Kidney / Q000503:physiopathology*; D008297:Male; D011817:Rabbits; D012082:Renal Veins; D013997:Time Factors
D004921:Erythropoietin
Eritropoéticheskaia funktsiia pochek v usloviiakh povyshennogo davleniia kisloroda