Multiple sclerosis: immunologic aspects.
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). Although the causes are not known, the pathogenesis likely involves complex relationships between autoimmunity, immunogenetics, immunologic deficiency and viral infection. The evidence for such interrelationships is discussed.
D001327:Autoimmune Diseases / Q000150:complications; D006801:Humans; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000150:complications; D009103:Multiple Sclerosis / Q000209:etiology / Q000235:genetics / Q000276:immunology*; D014777:Virus Diseases / Q000150:complications