Translocation +(7p+; Bq-) associated with recurrent abortion.
A balanced translocation was found in a normal female with a history of four abortions. On the basis of the Giemsa-banding pattern the abnormality was interpreted as to be a translocation of a part of the long arm of chromosome 13 to the short arm of chromosome some 7:t(7;13)(7qter leads to 7p22::13q14 leads to 13qter;13q14 leads to 13pter::7p22 leads to 7 pter). Problems in genetic counseling are discussed with respect to this case.
D000026:Abortion, Habitual / Q000235:genetics*; D002869:Chromosome Aberrations; D002901:Chromosomes, Human, 13-15; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D014178:Translocation, Genetic