Studies on the biosynthesis of basic 16-membered macrolide antibiotics, platenomycins. II. Production isolation and structures of 3-O-propionyl-5-O-mycaminosyl platenolides I and II, 9-dehydro demycarosyl platenomycin and demycarosyl platenomycin.
Four basic glycosides have been isolated from the fermentation broth of the blocked mutants of Streptomyces platensis subsp. malvinus MCRL 0388. These compounds isolated and purified by solvent extraction and column chromatography were identified as 3-O-propionyl-5-O-mycaminosyl platenolides I (PPL-I-MC) and II (PP-II-MC), 9-dehydro demycarosyl platenomycin (DDM-PLM) and demycarosyl platenomycin (DM-PLM).
D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000302:isolation & purification; D055598:Chemical Phenomena; D002621:Chemistry; D006027:Glycosides / Q000096:biosynthesis / Q000302:isolation & purification; D007783:Lactones / Q000096:biosynthesis / Q000302:isolation & purification; D009154:Mutation; D013302:Streptomyces / Q000378:metabolism; D014466:Ultraviolet Rays
D000900:Anti-Bacterial Agents; D006027:Glycosides; D007783:Lactones