[Effect of the mitochondrial ionophore for divalent cations on bilayer phospholipid membranes].
It has been shown that ionophore of bivalent cations (IBC) isolated from fatless, subjected to partial triptic hydrolysis cattle heart or liver mitochondria decreases BPM resistance inducing Ca2+ conductivity. Ions of lanthane in micromolar concentrations decrease calcium conductivity induced with IBC. When ten-fold gradient in Ca2+ was created on BPM the intitiation of the membrane potential fo 9-11 mV was observed. The role fo IBC and water soluble factors binding Ca2+ with high affinity, in the mitochrondial mechanism of Ca2+ translocation is discussed.
D000818:Animals; D001693:Biological Transport, Active; D002118:Calcium; D002413:Cations, Divalent; D002417:Cattle; D007811:Lanthanum; D008567:Membranes, Artificial; D008928:Mitochondria; D008930:Mitochondria, Liver; D010743:Phospholipids
D002413:Cations, Divalent; D008567:Membranes, Artificial; D010743:Phospholipids; D007811:Lanthanum; D002118:Calcium
Issledovaine éffekta mitokhondrialnogo ionofora dvukhvalentnykh kationov na bisloinye fosfolipidyne membrany