The mechanism of damage to neutrophils in allergic reactions in tuberculosis.
Allergic vulnerability of neutrophils due to pulmonary antigen and tuberculin in tuberculosis is connected with the fact that the immunological conflict antigen-antibody takes place on the surface of leukocytes. These two effects have a similar mechanism. The tissue antigen or tuberculin adsorbed on the cell surface with the participation of the complement may react with the corresponding circulating antibodies, thus producing damage to neutrophils.
D000042:Absorption; D000485:Allergens; D001323:Autoantibodies; D001324:Autoantigens; D001666:Binding Sites, Antibody; D003168:Complement Fixation Tests; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D007106:Immune Sera; D008168:Lung / Q000276:immunology; D009504:Neutrophils / Q000276:immunology*; D014373:Tuberculin; D014397:Tuberculosis, Pulmonary / Q000276:immunology*
D000485:Allergens; D001323:Autoantibodies; D001324:Autoantigens; D007106:Immune Sera; D014373:Tuberculin