The development of tibial dyschondroplasia in broiler chickens.
Two strains of broiler chickens selected for a high and a low incidence of tibial dyschondroplasia were fed a standard broiler starter ration with and without added chloride. Development of tibial dyschondroplasia was studied by radiography and serial necropsies. Lesions of tibial dyschondroplasia were mild in the low-incidence strain, regardless of ratio. The defect was more severe in the high-incidence strain and most severe in those birds fed the high-chloride ration. An abnormal thickening of the growth plate was apparent in the high-incidence strain as early as 2 weeks of age and became progressively more severe with age. No significant differences were noted in serum calcium, phosphorus, alkaline phosphatase, pCO2, or bone ash between strains of birds or between birds of the same strain fed different rations. Birds fed the high-chloride ration had a higher serum chloride and a lower serum bicarbonate and blood pH than birds on the standard ration.
D000818:Animals; D002356:Cartilage / Q000473:pathology; D002645:Chickens; D002712:Chlorides / Q000009:adverse effects; D004838:Epiphyses / Q000473:pathology; D010009:Osteochondrodysplasias / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D011201:Poultry Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D013977:Tibia / Q000473:pathology
D002712:Chlorides