A mathematical model of aging processes. III. Comments on the relative importance of serum cholesterol and blood pressure levels on mortality.
The distributions of serum cholesterol, blood pressure, and their values added together, were examined on a cross-sectional basis for a Montreal population. The results showed that all three distributions seem to be represented better by a log normal than by a normal distribution; but in each case, there was no pronounced increase in the skew with age. The distribution of the systolic blood pressure values exhibited an increasing variance with age, whereas the distribution of the serum cholesterol values remained approximately similar with age. The distribution of the two parameters added together also did not alter significantly with age. These results are consistent with the assumption that, if the serum cholesterol value of an individual changes, the individual will be placed at a substantially greater risk than if changes occur for blood pressure levels. Subpopulations of particular concern, with respect to changes in serum cholesterol levels, are those which undergo weight changes and those which smoke cigarettes.
D000328:Adult; D000368:Aged; D000375:Aging; D001794:Blood Pressure; D001835:Body Weight; D002784:Cholesterol / Q000097:blood; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D009026:Mortality; D012306:Risk; D012907:Smoking
D002784:Cholesterol