The effects of serotonin on feeding in the rabbit.
Serotonin infused through hepatic-portal cannulae of rabbits decreased food intake in a free-feeding condition. Following a 12 hr food deprivation period similar doses of serotonin increased food intake. Other investigators have shown release of serotonin to food and related stimuli. Our results demonstrate that serotonin is not a simple "satiety hormone" but suggest that it may be importantly involved in short-term regulatory mechanisms of feeding.
D000818:Animals; D004386:Duodenum / Q000502:physiology; D004435:Eating / Q000187:drug effects*; D005260:Female; D006503:Hepatic Veins; D007275:Injections, Intravenous; D011817:Rabbits; D011930:Reaction Time / Q000187:drug effects; D012527:Satiation / Q000187:drug effects; D012701:Serotonin / Q000494:pharmacology*; D014630:Vagus Nerve / Q000502:physiology
D012701:Serotonin