Modulation of the uptake and retention of estradiol-17beta in the ovine corpus luteum by luteinizing hormone.
The uptake and retention of 3H-estradiol by the ovine corpus luteum (induced by superovulation) was maximal through days 8-12 of the cycle with little or no uptake and retention during luteinization or regression. LH, but not FSH or prolactin, inhibited the uptake and retention of estradiol via stimulation of progesterone synthesis.
D000616:Aminoglutethimide / Q000494:pharmacology; D000818:Animals; D002470:Cell Survival; D003338:Corpus Luteum / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism*; D004964:Estriol / Q000494:pharmacology; D004970:Estrone / Q000494:pharmacology; D004971:Estrus; D005260:Female; D005640:Follicle Stimulating Hormone / Q000494:pharmacology; D008184:Luteal Cells / Q000378:metabolism*; D007986:Luteinizing Hormone / Q000494:pharmacology / Q000502:physiology*; D011247:Pregnancy; D011388:Prolactin / Q000494:pharmacology; D012756:Sheep; D013480:Superovulation; D013997:Time Factors; D014316:Tritium
D000616:Aminoglutethimide; D014316:Tritium; D004970:Estrone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D004964:Estriol