A simple chromatographic procedure for the concurrent estimation of urinary 4-hydroxy-3-methoxymandelic acid (HMMA) and homovanillic acid (HVA) using a scanning technique.
A rapid and simple procedure is described for the concurrent determination of 4-hydroxy-3-methoxymandelic acid (HMMA) and homovanillic acid (HVA). The acids are separated by chromatography and estimated by a scanning technique. The urinary output of HMMA and HVA over 24 h from 123 normals (80 males, 43 females) gave mean values of 3.3 +/- 0.94 and 4.9 +/- 1.3 mg, respectively. There was no significant difference in the 24 hour urinary output of HMMA and HVA between the male and femal groups.
D002854:Chromatography, Paper / Q000379:methods; D005069:Evaluation Studies as Topic; D006719:Homovanillic Acid / Q000652:urine*; D006801:Humans; D010648:Phenylacetates / Q000652:urine*; D014642:Vanilmandelic Acid / Q000652:urine*
D010648:Phenylacetates; D014642:Vanilmandelic Acid; D006719:Homovanillic Acid