A mathematical model for the determination of cardiac regurgitant and ejection fractions from radioisotope angiocardiograms.
A mathematical model taking into account the pulsatile pumping action of the heart has been developed which describes, in terms of a set of four recursive equations, the activity in the atrium and in the ventricle of the left or right heart at successive end-systoles and end-diastoles after bolus injection. The resulting closed form solutions permit calculations of chamber forward ejection fractions and valvular regurgitant fractions from computerized radioisotope angiocardiogram data. The method has been applied to a series of over thirty clinical studies with encouraging results.
D000790:Angiocardiography; D016275:Atrial Function; D001794:Blood Pressure; D006801:Humans; D008433:Mathematics; D008722:Methods; D008954:Models, Biological; D009200:Myocardial Contraction; D016276:Ventricular Function