Inhibitory effect of flavin mononucleotide on the hemolysis of rabbit erythrocytes by staphylococcal alpha-toxin.
Flavin mononucleotide diminished the hemolytic action of staphylococcal alpha-toxin on rabbit erythrocytes by competitive inhibition, probably by its interaction with the alpha-toxin binding sites on the cell membrane.
D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D002462:Cell Membrane / Q000276:immunology; D004912:Erythrocytes / Q000187:drug effects*; D005486:Flavin Mononucleotide / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects*; D011402:Pronase; D011817:Rabbits; D012256:Riboflavin / Q000378:metabolism; D013211:Staphylococcus aureus / Q000276:immunology*; D014118:Toxins, Biological / Q000494:pharmacology*
D014118:Toxins, Biological; D005486:Flavin Mononucleotide; D011402:Pronase; D012256:Riboflavin