Complications of abdominal exploration and splenectomy in staging children with Hodgkin's disease.
Until alternate diagnostic methods are discovered, the staging procedure seems to be the most reliable method to establish the presence or absence of abdominal involvement in Hodgkin's disease. Our experience with staging laparotomy in 22 children raises serious questions as to both the risk of operation and the prognostic value of a negative abdominal exploration. Routine use of the staging laparotomy may not be justified in clinical Stage IA patients with lymphocyte-predominant cell type. Because of the hazards and limitations of the staging procedure, vigorous attempts would seem to be indicated to identify subcategories of patients in whom the likelihood of intraabdominal involvement is so small as to negate the value of surgical staging.
D000293:Adolescent; D001706:Biopsy / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D004660:Encephalitis / Q000209:etiology; D005260:Female; D005402:Fistula / Q000209:etiology; D006562:Herpes Zoster / Q000209:etiology; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D007238:Infarction / Q000209:etiology; D007415:Intestinal Obstruction / Q000209:etiology; D007421:Intestine, Small / Q000098:blood supply; D007443:Intussusception / Q000209:etiology; D007583:Jejunum; D007813:Laparotomy / Q000009:adverse effects; D008206:Lymphatic Diseases / Q000209:etiology; D008297:Male; D011183:Postoperative Complications; D013156:Splenectomy / Q000009:adverse effects*