Hysterectomy of the newborn guinea-pig, subsequent effects on the oestrous cycle and life span of the corpora lutea.
Longer oestrous cycles result from neonatal hysterectomy than from hysterectomy in adult life. Section and cauterization of the utero-vaginal union also prolonged the vaginal closure period up to an average of 55 days. The destruction of the mesometrium did not lengthen the oestrous cycle. Uterine autografts in hysterectomized newoborn guinea-pigs did not prevent the long cycles.
D000818:Animals; D000831:Animals, Newborn; D003340:Corpus Luteum Maintenance; D004958:Estradiol / Q000494:pharmacology; D004971:Estrus / Q000187:drug effects; D005260:Female; D006168:Guinea Pigs; D007044:Hysterectomy; D008026:Ligation; D011247:Pregnancy; D013997:Time Factors; D014599:Uterus / Q000502:physiology*
D004958:Estradiol