Hypercalcaemia in chronic lymphatic leukaemia.
Hypercalcaemia developed in a patient with chronic lymphatic leukaemia. The hypercalcaemia did not respond to conventional treatment. At bone biopsy osteoclastic resorption was found (a photomicrograph is presented). 7 cases from the literature of hypercalcaemia and chronic lymphatic leukaemia are briefly reviewed. Possible mechanisms are discussed and it is suggested that osteoclast-stimulating factors may be of importance in the development of the hypercalcaemia.
D000368:Aged; D001706:Biopsy; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D007085:Ilium / Q000473:pathology; D007945:Leukemia, Lymphoid / Q000097:blood / Q000150:complications* / Q000473:pathology; D008297:Male; D010010:Osteoclasts