[Results of a pharmacological and toxicological study of pentagastrin].
Pentagastrin is found to be a highly active stimulator of the gastric glands secretion. With its intraperitoneal introduction to albino rats the drug displays a low acute toxicity. On its re-administration to rabbits and albino rats in doses significantly exceeding the diagnostic ones no substantial influence on the growth of the animals, hematological, enzymological, proteinological blood indices and morphological condition of internal organs was noted.
D000818:Animals; D001769:Blood / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005750:Gastric Juice / Q000187:drug effects / Q000378:metabolism; D006632:Histamine / Q000494:pharmacology; D007844:Latvia; D010418:Pentagastrin / Q000494:pharmacology* / Q000633:toxicity; D011817:Rabbits; D051381:Rats; D012636:Secretory Rate / Q000187:drug effects; D013268:Stimulation, Chemical
D006632:Histamine; D010418:Pentagastrin
Rezul'taty farmakologicheskogo i toksikologicheskogo izucheniia pentagastrina