Effects of long-term treatment with metiamide.
Metiamide was given to patients with peptic ulcer or oesophagitis in a pilot study to establish the therapeutic value of the drug. Administration of metiamide resulted in relief of pain within a week in the majority of patients. Healing of duodenal and gastric ulcers was observed.
D004381:Duodenal Ulcer / Q000188:drug therapy*; D004941:Esophagitis / Q000188:drug therapy; D005745:Gastric Acidity Determination; D005750:Gastric Juice / Q000378:metabolism; D006801:Humans; D008785:Metiamide / Q000009:adverse effects / Q000627:therapeutic use*; D009325:Nausea / Q000139:chemically induced; D010146:Pain; D010195:Pancreatitis / Q000188:drug therapy; D012636:Secretory Rate / Q000187:drug effects; D013268:Stimulation, Chemical; D013276:Stomach Ulcer / Q000188:drug therapy*; D013890:Thiourea / Q000031:analogs & derivatives*; D013997:Time Factors
D008785:Metiamide; D013890:Thiourea