Methadone-induced pulmonary edema.
A patient with methadone-induced pulmonary edema had increased extravascular water in the lungs and a reduced total vascular albumin space. Diuresis resulted in hypotension. These observations suggest that the appropriate treatment of this condition should be ventilatory support and restoration of plasma oncotic pressure with albumin. Diuretic therapy should be used with caution.
D000328:Adult; D001834:Body Water; D002199:Capillary Permeability / Q000187:drug effects; D004232:Diuretics / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D008297:Male; D008691:Methadone; D011654:Pulmonary Edema / Q000139:chemically induced* / Q000628:therapy; D012121:Respiration, Artificial; D012709:Serum Albumin / Q000032:analysis; D019966:Substance-Related Disorders
D004232:Diuretics; D012709:Serum Albumin; D008691:Methadone