[Tuberculin allergy in BCG-vaccinated children (author's transl)].
Frequency, duration and intensity of tuberculin allergy was tested in 431 children, vaccinated as neonates, and compared with the data of 400 non-vaccinated children, and 30 children with tuberculosis. When tested with 100 TE, 59% of the vaccinees showed a positive reaction at the age of 5 years, still 36% reacted positively in the 7th year. 4,7% of the non-vaccinated children were tuberculin-positive in 7--9 years old. Near half of the children reacting positively to tuberculin without suffering from tuberculosis reacted to 100 TE, nearly all tuberculous children already reacted positively to a lower dose. The overall rate of protection against tuberculosis was more than 90% in the first 5 years of life. Miliar-Tb. or Tb-meningitis was not seen in vaccinees, but 4 times in non protected children. General BCG-vaccination in newborns is recommended.
D000367:Age Factors; D001500:BCG Vaccine; D002648:Child; D002675:Child, Preschool; D004342:Drug Hypersensitivity; D006801:Humans; D007231:Infant, Newborn; D013997:Time Factors; D014374:Tuberculin Test / Q000009:adverse effects*; D014376:Tuberculosis / Q000175:diagnosis / Q000517:prevention & control*; D014390:Tuberculosis, Meningeal / Q000517:prevention & control; D014391:Tuberculosis, Miliary / Q000517:prevention & control
D001500:BCG Vaccine
Tuberkulin-Allergie bei BCG-geimpften Kindern