Drug delivery systems for topical ophthalmic medication.
Two new topical ophthalmic delivery systems are described. The modes of delivery were compared with conventionally administered eyedrops on the basis of intraocular pressure lowering effect, dependability in delivery of prescribed dosage, and patient acceptance of the system. Pilocarpine delivered by each of the systems was found to control IOP as well as conventional pilocarpine drops. Although some patients took a longer time than others to adjust to a new mode of delivery, patient acceptance of the systems was high.
D000287:Administration, Topical; D000328:Adult; D000336:Aerosols; D000368:Aged; D003692:Delayed-Action Preparations; D005069:Evaluation Studies as Topic; D005260:Female; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D010342:Patient Acceptance of Health Care; D010862:Pilocarpine / Q000008:administration & dosage*
D000336:Aerosols; D003692:Delayed-Action Preparations; D008567:Membranes, Artificial; D009883:Ophthalmic Solutions; D010862:Pilocarpine