[Excretion of delta-aminolevulinic acid during combined radiotherapy of patients with cervix carcinoma. 2. Medical check-ups for lead in the Vienna area among various occupational and personal groups].
A report is given of an increase in urinary delta-aminolaevulinic acid (ALA) excretion in patients with cervical carcinoma treated by extracorporeal radiotherapy as well as with radium and telecobalt. It was found, that 16 out of 17 patients showed an increase of 125% (on average) in the elimination of ALA on the seventh day after irradiation. A return to noraml ALA-values was found in nine patients 42 days after radiotherapy whilst in six patients a further increase in ALA elimination occurred in comparison with the values recorded on the seventh post-irradiation day. The possible causes of the lead elimination, indicated by the ALA test, as well as the possibility of lead as an aetiological factor in tumour genesis are discussed.
D000622:Aminolevulinic Acid / Q000652:urine*; D001842:Bone and Bones / Q000378:metabolism; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005112:Extracorporeal Circulation; D005260:Female; D006801:Humans; D007854:Lead / Q000009:adverse effects / Q000378:metabolism; D007982:Levulinic Acids / Q000652:urine*; D009369:Neoplasms / Q000139:chemically induced; D011832:Radiation Injuries / Q000378:metabolism; D011867:Radioisotope Teletherapy; D011878:Radiotherapy / Q000379:methods; D011883:Radium / Q000627:therapeutic use; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy / Q000652:urine*
D003037:Cobalt Radioisotopes; D007982:Levulinic Acids; D007854:Lead; D000622:Aminolevulinic Acid; D011883:Radium
Uber die delta-Aminolävulinsäure-Ausscheidung sährend einer kombinierten Strahlentherapie von Patientinnen mit Carcinoma colli uteri. 2. Mitteilung über Blei-Vorsorgeuntersuchungen im Raume Wien bei verschiedenen Berufsund Personengruppen