Proline biosynthesis and degradation in mammalian cells and tissue.
Radioisotopic assays have been developed for the enzymes of proline metabolism. These assays are specific and sensitive enough to measure enzyme activities in cultured cells and biopsy specimens. Measurements of these enzymes in tissues and cultured cells suggest that endogenous biosynthesis of proline may be an important source of this amino acid.
D000818:Animals; D002460:Cell Line; D066298:In Vitro Techniques; D009953:Ornithine-Oxo-Acid Transaminase / Q000378:metabolism; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000378:metabolism; D011392:Proline / Q000096:biosynthesis / Q000378:metabolism*
D011392:Proline; D000587:Oxidoreductases Acting on CH-NH Group Donors; D009953:Ornithine-Oxo-Acid Transaminase