Passage of the intravenously administered 15N urea into the digestive tract and its excretion in the sheep.
The experiments performed on two wethers provided with simple rumen cannulas and reentrant cannulas, inserted into the proximal duodenum and ileum, showed a passage of 15N from labelled urea, injected intravenously, from the blood to the digestive tract. The amount of the 15N in the digesta was the highest in duodenum, slightly lower in the rumen and slightly lower in ileum. Approximately 50% of the injected 15N was excreted in urine. The amount of the 15N eliminated with feces was very small; 0.6 to 2.8% of the dose injected per day. About 73--84% of the 15N which passed the duodenum was absorbed in further parts of the digestive tract. It can be concluded that all parts of the digestive tract take part in utilization of the endogenous urea.
D000818:Animals; D004386:Duodenum / Q000378:metabolism*; D005243:Feces / Q000032:analysis; D007082:Ileum / Q000378:metabolism*; D007275:Injections, Intravenous; D008297:Male; D009587:Nitrogen Isotopes; D012417:Rumen / Q000378:metabolism*; D012756:Sheep / Q000502:physiology*; D014508:Urea / Q000008:administration & dosage / Q000378:metabolism* / Q000652:urine
D009587:Nitrogen Isotopes; D014508:Urea