[Insensitivity of stationary cultures of transformed mouse fibroblasts to agents stimulating DNA synthesis in normal cell cultures].
Stationary cultures of the mouse transformed cells L and S-40 sensitive to topoinhibition were found to be insensitive to the action of hyaluronidase, RNAase, and colcemid in doses known to stimulate multiplication of normal mouse fibroblasts. These cultures were still insensitive to the action of medium change and removal of a part of the monolayer.
D000818:Animals; D002471:Cell Transformation, Neoplastic; D004247:DNA / Q000096:biosynthesis*; D004273:DNA, Neoplasm / Q000096:biosynthesis; D003703:Demecolcine / Q000494:pharmacology*; D005347:Fibroblasts / Q000187:drug effects; D006821:Hyaluronoglucosaminidase / Q000494:pharmacology*; D007739:L Cells / Q000187:drug effects; D051379:Mice; D012260:Ribonucleases / Q000494:pharmacology*
D004273:DNA, Neoplasm; D004247:DNA; D012260:Ribonucleases; D006821:Hyaluronoglucosaminidase; D003703:Demecolcine
Nechuvstvitel'nost' gustykh kul'tur transformirovannykh myshinykh fibroblastov k deĭstviiu agentov, stimuliruiushchikh sintez DNK v kul'turakh normal'nykh kletok