Gradation of the reflex response from atrial receptors.
1. In anaesthetized dogs, distension of balloons so as to stimulate atrial receptors resulted in a reflex increase in heart rate. 2. Successive distensions of one, two and three balloons positioned in the left upper and middle pulmonary vein-atrial junctions and in the left atrial appendage resulted in a progressive increase in the magnitude of this response. 3. It is concluded that the magnitude of the increase in heart rate is related to the extent of receptor area stimulated.
D000818:Animals; D016275:Atrial Function; D001794:Blood Pressure; D001950:Bretylium Tosylate / Q000494:pharmacology; D004285:Dogs; D006321:Heart / Q000187:drug effects; D006325:Heart Atria / Q000294:innervation*; D006339:Heart Rate; D010812:Physical Stimulation; D011311:Pressoreceptors / Q000502:physiology*; D011667:Pulmonary Veins / Q000502:physiology; D012018:Reflex; D013564:Sympathetic Nervous System / Q000187:drug effects
D001950:Bretylium Tosylate