Appearance of acetylcholinesterase and creatine kinase in plasma of normal chickens after denervation.
Evidence that acetylcholinesterase (AChE) activity is released from normal chick embryonic muscle fibers and from muscles of chickens with inherited muscular dystrophy suggested that denervated chick muscles, which have AChE properties similar to dystrophic muscles, would also release AChE. Bilateral denervation of the breast and wing muscles of normal chickens was followed by the appearance of AChE activity, distinguished from plasma cholinesterase by differential substrate hydrolysis, inhibitor sensitivity, and electrophoretic migration. Plasma creatine kinase (CK) activity was also elevated after denervation.
D000110:Acetylcholinesterase / Q000097:blood*; D000818:Animals; D002091:Butyrylcholinesterase / Q000097:blood; D002645:Chickens / Q000097:blood*; D003402:Creatine Kinase / Q000097:blood*; D009121:Muscle Denervation; D013997:Time Factors
D003402:Creatine Kinase; D000110:Acetylcholinesterase; D002091:Butyrylcholinesterase