Enhanced hepatotoxicity of carbon tetrachloride, thioacetamide, and dimethylnitrosamine by pretreatment of rats with ethanol and some comparisons with potentiation by isopropanol.
D000433:1-Propanol / Q000494:pharmacology*; D000079:Acetaldehyde / Q000494:pharmacology; D000081:Acetamides / Q000633:toxicity*; D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000503:physiopathology*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000473:pathology; D004128:Dimethylnitrosamine / Q000633:toxicity*; D004357:Drug Synergism; D000431:Ethanol / Q000097:blood / Q000494:pharmacology*; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism / Q000473:pathology; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009602:Nitrosamines / Q000633:toxicity*; D051381:Rats; D013853:Thioacetamide / Q000633:toxicity*
D000081:Acetamides; D009602:Nitrosamines; D013853:Thioacetamide; D000431:Ethanol; D000433:1-Propanol; D006899:Mixed Function Oxygenases; D000410:Alanine Transaminase; D000079:Acetaldehyde; D004128:Dimethylnitrosamine