Human alpha-lactalbumin: measurement in serum and in breast cancer organ cultures by radioimmunoassay.
A sensitive and specific radioimmunoassay for human alpha-lactalbumin, a major milk protein, is described. Some normal men and women have detectable levels of alpha-lactalbumin in their blood. High values are found in nursing mothers and many patients with galactorrhea. Alpha-Lactalbumin is found in some breast cancer organ cultures. In addition, alpha-lactalbumin output was stimulated by ovine prolactin in 2 of the 19 tumors studied.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000032:analysis* / Q000097:blood; D002277:Carcinoma / Q000032:analysis / Q000097:blood; D002648:Child; D005260:Female; D005687:Galactorrhea / Q000097:blood; D006801:Humans; D007768:Lactalbumin / Q000032:analysis* / Q000097:blood; D007774:Lactation; D008297:Male; D008875:Middle Aged; D009924:Organ Culture Techniques; D011247:Pregnancy; D011388:Prolactin / Q000502:physiology
D011388:Prolactin; D007768:Lactalbumin