Spectrophotometric determination of acetaminophen and dichloralantipyrine in capsules.
A rapid method for the routine determination of acetaminophen and dichloralantipyrine in capsules is reported. The determination of acetaminophen is based on the ability of its hydrolytic product, p-aminophenol, to produce an intensive yellow color with vanillin. The determination of dichloralantipyrine is based on the fact that it, as well as its major metabolite chloral hydrate, produces a blue color with quinaldine ethiodide. No interferences were encountered, and good recovery and precision data were obtained.
D000082:Acetaminophen / Q000032:analysis*; D000983:Antipyrine / Q000031:analogs & derivatives* / Q000032:analysis; D002214:Capsules / Q000032:analysis; D008722:Methods; D013056:Spectrophotometry, Ultraviolet
D002214:Capsules; D000082:Acetaminophen; D000983:Antipyrine