Elevation of left ventricular end-diastolic pressure due to decreased myocardial compliance during angina pectoris.
The etiology for the increased left ventricular end-diastolic pressure (LVEDP), which is frequently seen during angina pectoris, remains controversial. Although left ventricular failure may be present, recent evidence suggests that a decrease in myocardial compliance may be involved. The patient reported here developed a rise in LVEDP when angina was precipitated by atrial pacing. Hemodynamic data during and after pacing showed normal left ventricular function and indicates that a decrease in myocardial compliance should have occurred.
D000787:Angina Pectoris / Q000503:physiopathology*; D001794:Blood Pressure; D002302:Cardiac Output; D003187:Compliance; D003326:Coronary Circulation; D006321:Heart / Q000503:physiopathology*; D006339:Heart Rate; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged