A renin-like activity in pineal gland and hypophysis.
The presence and distribution of renin-like activity in hypophysis, pineal gland and some neural tissues were studies in both normal and salt-loaded rats. The Boucher micromethod was used to detect enzymatic activity. In normal rats both the pituitary and pineal glands contained significantly higher values of renin-like activity than did the other tissues examined. In salt-loaded animals there was a significant decrease of the renin-like activity of the glandular tissue while in the other brain areas the activity increased. The results are discussed in terms of the possible physiological role of the central renin-angiotensin system in the regulation of fluid and electrolyte balance.
D000818:Animals; D001921:Brain / Q000201:enzymology; D005260:Female; D010870:Pineal Gland / Q000201:enzymology*; D010902:Pituitary Gland / Q000201:enzymology*; D011247:Pregnancy; D051381:Rats; D012083:Renin / Q000378:metabolism*; D014882:Water-Electrolyte Balance
D012083:Renin