[Proceedings: Sulpiride effects on plasmatic gonadotropins in women (author's transl)].
The study of longitudinal evolution of plasmatic gonadotropins in women receiving sulpirid, a psychotropic drug with a strong anti-ovulatory effect, shows the coexistence of anovulation and the peristance of a physiological pattern of gonadotropins during the first cycle of treatment. It also shows the persistance of LH peaks comparable to preovulatory levels more than one year after the initiation of therapy. However, the basal line became very unsteady. This study suggests the presence of two types of perturbations with sulpirid. A hypothalamic-hypophyseal mild action and, an ovarian resistance to gonadotropins resulting from the hyperprolactinism induced by sulpirid.
D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood*; D008598:Menstruation / Q000187:drug effects; D013469:Sulpiride / Q000494:pharmacology*
D013469:Sulpiride; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Evolution des gonadotrophines plasmatiques féminines sous sulpiride