Resistance of W/Fu rats to adrenal regeneration hypertension.
The procedure for producing adrenal regeneration hypertension did not cause an increase in the systolic blood pressure of W/Fu animals. The regenerating adrenal gland in W/Fu animals was not restored to normal; reduced numbers of mitochondrial cristae were seen and the mitochondria were smaller in size; regeneration was complete in Sprague-Dawley rats of the Holtzman strain and there was a severe form of hypertensive, cardiovascular disease.
D000302:Adrenal Cortex / Q000502:physiology*; D000311:Adrenal Glands / Q000502:physiology* / Q000648:ultrastructure; D000818:Animals; D005260:Female; D006973:Hypertension / Q000503:physiopathology*; D008928:Mitochondria / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains / Q000502:physiology*; D011920:Rats, Inbred WF / Q000502:physiology*; D012038:Regeneration; D013045:Species Specificity