Lipase and co-lipase activities of human small intestinal contents after a liquid test meal.
Methods for the determination of pancreatic lipase in small intestinal content have been re-evaluated in the light of the presence of co-lipase therein. A method is described for the determination of co-lipase in intestinal content based on its property to reactivate bile-salt-inhibited lipase. Figures are given for lipase and co-lipase activities in intestinal contents of normal humans aged 1-22. These two components originating in the pancreatic juice vary in a parallel fashion, and no variations with age were apparent. A simple diagnostic criterion is given to detect a possible specific co-lipase deficiency.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003067:Coenzymes / Q000378:metabolism*; D005502:Food; D006801:Humans; D007223:Infant; D007421:Intestine, Small / Q000201:enzymology*; D008049:Lipase / Q000378:metabolism*; D010179:Pancreas / Q000201:enzymology; D010189:Pancreatic Juice / Q000201:enzymology
D003067:Coenzymes; D008049:Lipase