Effect of amantadine on blood pressure responses induced by vagal and sympathetic stimulation.
Amantadine antagonizes the blood pressure responses evoked by electrical stimulation of the central and peripheral end of the vagus. Blood pressure responses on sympathetic stimulation are also attenuated. These results could be explained on the basis of a possible effect on autonomic ganglia.
D000547:Amantadine / Q000494:pharmacology*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D002415:Cats; D003864:Depression, Chemical; D004558:Electric Stimulation; D005260:Female; D008297:Male; D051381:Rats; D013116:Spinal Cord / Q000502:physiology; D013564:Sympathetic Nervous System / Q000502:physiology*; D014043:Tolazoline / Q000494:pharmacology; D014628:Vagotomy; D014630:Vagus Nerve / Q000502:physiology*
D000547:Amantadine; D014043:Tolazoline