[Oral iron therapy in infancy and childhood (author's transl)].
In pediatric practice iron deficiency is the most common nutritional deficiency. Infants between 6 months and 2 or 3 years are predisposed, especially if they were pre- or dysmature newborns or gemini. The frequency of iron deficiency--prelatent, latent or manifest anemia -- can be understood from the peculiarities of iron metabolism in this early period of life. Influencing factors are the body iron content of the newborn and the amount of postnatal iron intake. The discrepancy between a low iron content in the average baby's formula and high requirements in the rapidly growing organism have also to be considered. Low values of hemoglobin and serum iron, and an increased intestinal iron absorption in a normal baby of 4--6 months or a prematurely born baby of 2--3 months indicate depleted iron stores. A longterm oral iron therapy is indicated in pre- or dysmature babies, in newborns with perinatal blood loss, and in infants with recurrent infections. In this study 40 infants and children were treated with a liquid ferrogluconate preparation (Athensa-Ferro-Saft). Controls of several parameters of red blood cells, serum iron and iron binding capacity showed a good or excellent therapeutic effect. No serious side effects were seen. Because the preparation is well tolerated and can be administered in individual doses, it may be recommended for pediatric use.
D000284:Administration, Oral; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004906:Erythrocyte Count; D005260:Female; D005942:Gluconates / Q000008:administration & dosage / Q000627:therapeutic use*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007501:Iron / Q000008:administration & dosage / Q000009:adverse effects / Q000097:blood / Q000627:therapeutic use*; D011247:Pregnancy; D011485:Protein Binding; D013997:Time Factors; D014427:Twins
D005942:Gluconates; D006454:Hemoglobins; D007501:Iron
Orale Eisentherapie im Säuglings- und Kindesalter. Erfahrungen mit einer modifizierten Eisengluconat-Zubereitung