Activities of kidney decarboxylases of histidine and ornithine in adrenalectomized mice substituted with cortisone.
In adrenalectomized mice, cortisone inhibited histidine decarboxylase of the kidney in a dose-related manner. The effect of cortisone on ornithine decarboxylase was diphasic: small doses elevated, high doses inhibited.
D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D001835:Body Weight; D002262:Carboxy-Lyases / Q000378:metabolism*; D003348:Cortisone / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006640:Histidine Decarboxylase / Q000378:metabolism*; D007668:Kidney / Q000201:enzymology*; D051379:Mice; D009929:Organ Size; D009955:Ornithine Decarboxylase / Q000378:metabolism*
D002262:Carboxy-Lyases; D009955:Ornithine Decarboxylase; D006640:Histidine Decarboxylase; D003348:Cortisone