Sialic acid containing abnormal amylases in human sera.
The properties of abnormal amylases with unusually fast electrophortetic mobility from five patients were studied. These abnormal amulases showed markedly reduced electrophoretic migration to the cathodic side by digestion with neuraminidase. It was suggested that these five abnormal amylases contained sialic acid in their molecules, and the increased electrophorectic mobility resulted from sialic acid, which is not present in normal human amylases.
D000681:Amylases / Q000032:analysis / Q000097:blood*; D004588:Electrophoresis, Cellulose Acetate; D006801:Humans; D007527:Isoenzymes / Q000032:analysis / Q000097:blood*; D008175:Lung Neoplasms / Q000201:enzymology; D009107:Mumps / Q000201:enzymology; D009928:Organ Specificity; D010179:Pancreas / Q000201:enzymology; D010195:Pancreatitis / Q000201:enzymology; D012463:Saliva / Q000201:enzymology; D012794:Sialic Acids / Q000032:analysis*
D007527:Isoenzymes; D012794:Sialic Acids; D000681:Amylases