A local outbreak of paralytic rabies in Surinam children.
A rapidly fatal encephalomyelitis, which was in most cases characterized by ascending paralysis, developed in seven children of the age of 3 to 10 years in a bushnegro village in the interior of Surinam. Rabies virus was recovered from the central nervous system of three autopsied children. Although the source of infection has not been detected, there is an indication that, at least in some cases, the disease has been transmitted by rat-bite rather than by vampire bats. During the same period a few cases of minor febrile illness occurred in the same community. Since virological and serological evidence of a wide-spread distribution of Coxsackie A virus type 4 was obtained, the latter illness may presumably be attributed to this virus.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D002490:Central Nervous System / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000453:epidemiology*; D004679:Encephalomyelitis / Q000453:epidemiology / Q000382:microbiology; D004770:Enterovirus / Q000276:immunology / Q000302:isolation & purification; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D010243:Paralysis / Q000453:epidemiology; D011817:Rabbits; D011818:Rabies / Q000453:epidemiology* / Q000382:microbiology / Q000635:transmission; D011820:Rabies virus / Q000276:immunology / Q000302:isolation & purification; D051381:Rats; D013532:Suriname
D000914:Antibodies, Viral