Biliary lipid composition in early childhood.
The biliary lipid composition was studied in 11 children without hepatic or gastrointestinal disease who ranged in age from 15 to 54 months. The molar percentages of cholesterol, bile acids and phospholipids in the biliary lipid mixture averaged 5.0 +/- 1.1; 80 +/- 6.1 and 15 +/- 6.2%, respectively. Cholic, chenodeoxycholic, deoxycholic and ursodeoxycholic acid comprised 48; 45; 4 and 3% of total bile acids, respectively. A comparison of the lipid composition with data reported in the literature for the adult reveals that the molar percentage of cholesterol is relatively low in early childhood. This could be one of the factors which is responsible for the low incidence of cholesterol gallstones in this age group.
D000328:Adult; D001646:Bile / Q000032:analysis*; D001647:Bile Acids and Salts / Q000032:analysis; D002675:Child, Preschool; D002784:Cholesterol / Q000032:analysis; D002793:Cholic Acids / Q000032:analysis; D005260:Female; D006801:Humans; D007223:Infant; D008055:Lipids / Q000032:analysis*; D008297:Male; D010743:Phospholipids / Q000032:analysis
D001647:Bile Acids and Salts; D002793:Cholic Acids; D008055:Lipids; D010743:Phospholipids; D002784:Cholesterol