Infiltrative retinopathy in systemic lymphoma.
A 48-year-old woman with a diffuse well-differentiated lymphocytic lymphoma developed an unusually extensive bilateral infilfrative retinopathy during a period of quiescence of her systemic illness. Although radiation therapy to each orbit initially induced clearing of the infiltration and significant improvement in visual acuity, late visual acuity loss due to retinal and optic nerve changes ensued.
D003035:Cobalt / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D005134:Eye Neoplasms / Q000473:pathology* / Q000628:therapy; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi / Q000473:pathology; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009900:Optic Nerve / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D011736:Pyridoxine / Q000627:therapeutic use; D012160:Retina / Q000473:pathology*; D012166:Retinal Hemorrhage / Q000209:etiology; D014750:Vincristine / Q000627:therapeutic use; D014792:Visual Acuity
D003035:Cobalt; D014750:Vincristine; D003520:Cyclophosphamide; D011736:Pyridoxine; D007538:Isoniazid; D011241:Prednisone