[Pain-alleviating action of fentanyl and pentazocine in combination with droperdol and carbidine].
Tests staged on rabbits showd that analgesic (phentanyl and pentasocine), neuroleptics (droperidol and carbidine) and their combinations produce a more pronounced and analgesic action with an electric irritation of the dental tissues than with that of the rabbit's paw. Neuroleptanalgesic mixtures containing pentasocine display a somewhat weaker analgesic activity, but their effect lasts longer and they have a less marked influence on the respiration. Mixtures containing cabidine in lieu of droperidol produce a somewhat greater analgesic effect and relax and skeletal muscles less.
D000766:Anesthesia, Dental / Q000379:methods; D000818:Animals; D002243:Carbolines / Q000627:therapeutic use*; D002415:Cats; D004329:Droperidol / Q000627:therapeutic use*; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D005283:Fentanyl / Q000627:therapeutic use*; D007211:Indoles / Q000627:therapeutic use*; D009458:Neuroleptanalgesia; D010423:Pentazocine / Q000627:therapeutic use*; D011817:Rabbits; D014070:Tooth / Q000187:drug effects; D014098:Toothache / Q000188:drug therapy*; D014149:Tranquilizing Agents / Q000627:therapeutic use*
D002243:Carbolines; D004338:Drug Combinations; D007211:Indoles; D014149:Tranquilizing Agents; D004329:Droperidol; D010423:Pentazocine; D005283:Fentanyl
Boleutoliaiushchee deĭstvie fentanila i pentazotsina v kombinatsii s droperidolom i karbidinom