Kinetics of the single-strand repair mechanism in mammalian cells.
Alkaline sucrose gradient measurements of single-strand breaks from sublethal X-ray doses yield the same breakage efficiency as from lethal doses. Repair of the breaks is random, first order with a single rate constant, and characterized by 24 kcal/mole activation energy.
D002460:Cell Line; D003201:Computers; D004260:DNA Repair; D004277:DNA, Single-Stranded / Q000096:biosynthesis / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D007700:Kinetics; D011830:Radiation Effects
D004277:DNA, Single-Stranded