Thiamine absorption in the rat. III. Effect of ethyl alcohol on active absorption of thiamine in-vitro.
The effect of ethanol on active thiamine absorption in-vitro was studied in everted sacs of rat small intestines. Non-adapted, normally fed rats were used which had not previously been treated with alcohol. It was found that ethanol at 1% final concentration significantly increased active transport of thiamine to approximately fourfold. It is suggested that increased permeability of the intestinal wall plays a major role in phenomenon.
D000818:Animals; D000431:Ethanol / Q000494:pharmacology*; D066298:In Vitro Techniques; D007408:Intestinal Absorption / Q000187:drug effects; D007421:Intestine, Small / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D051381:Rats; D013268:Stimulation, Chemical; D013831:Thiamine / Q000378:metabolism*
D000431:Ethanol; D013831:Thiamine