Blastomycosis of the genitourinary tract.
In a retrospective study of 51 cases of systemic North American blastomycosis 11 patients were found to have genitourinary tract involvement, the prostate and epididymis being most commonly affected. Diagnosis was made by culture of the fungus from urine, abscess or prostate secretions, morphologic identification of the characteristic organism in urine or secretions, or histologic examination of tissue specimens. Treatment with amphotericin B reduced the mortality rate of 90 per cent to as low as 10 per cent. Long-term followup is necessary because of a relapse rate of 10 to 15 per cent.
D000328:Adult; D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D001759:Blastomycosis / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D004823:Epididymitis / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D005832:Genital Diseases, Male / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010409:Penile Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D011193:Potassium Iodide / Q000627:therapeutic use; D011469:Prostatic Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D013266:Stilbamidines / Q000009:adverse effects / Q000627:therapeutic use; D013733:Testicular Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery
D013266:Stilbamidines; D011193:Potassium Iodide; D000666:Amphotericin B