Polymerization of sperm actin in the presence of cytochalasin-B.
The polymerization of globular actin to fibrous actin which occurs when sperm are activated, was not inhibited by cytochalasin-B. The acrosomal filament and its component actin filaments formed in the presence of cytochalasin-B; and once formed, the actin filaments did not depolymerize when exposed to cytochalasin-B.
D000177:Acrosome / Q000187:drug effects / Q000648:ultrastructure; D000199:Actins; D000818:Animals; D003571:Cytochalasin B / Q000494:pharmacology*; D005260:Female; D008297:Male; D011108:Polymers; D012617:Sea Urchins; D012623:Seawater; D013094:Spermatozoa / Q000187:drug effects*; D013215:Starfish
D000199:Actins; D011108:Polymers; D003571:Cytochalasin B