Enhanced plutonium absorption in iron-deficient mice.
The total body burden of plutonium 24 or 96 hr following a single gastric intubation was approximately fourfold greater in iron-deficient than in iron-replete mice. There was also a more rapid translocation of plutonium from soft tissues to bone in the iron-deficient mice by 96 hr after gavage. In the iron-replete group only liver concentrations of plutonium increased during the corresponding time period.
D000818:Animals; D005269:Femur / Q000378:metabolism; D007501:Iron / Q000097:blood; D000090463:Iron Deficiencies; D008099:Liver / Q000378:metabolism; D051379:Mice; D008813:Mice, Inbred ICR; D011005:Plutonium / Q000378:metabolism*; D013997:Time Factors
D011005:Plutonium; D007501:Iron