Hansch analysis of interaction of haptens with benzylpenicilloyl antibodies.
Hansch analysis is applied to inhibition data obtained from the interaction of penicilloic and penilloic acid haptens with benzylpenicilloyl specific antibodies. Significant regressions with partition coefficient and molar volume parameters indicate the importance of hydrophobic and steric effects in these interactions.
D000906:Antibodies; D000937:Antigen-Antibody Reactions; D004903:Erythrocyte Aggregation / Q000187:drug effects; D006241:Haptens / Q000494:pharmacology*; D007700:Kinetics; D010400:Penicillin G / Q000276:immunology*; D010406:Penicillins / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000906:Antibodies; D006241:Haptens; D010406:Penicillins; D010400:Penicillin G