Intramitochondrial bodies in a human cell line carrying oncornavirus-like particles.
Electron-dense particles 80-100 nm in diameter were observed in electron micrographs of mitochondria in transformed mouse fibroblasts and in a human amnion cell line infected with supernatants of a human mammary carcinoma cell culture. Intramitochondrial particles were more numerous in the human cell cultures early after subculture. These particles were morphologically similar to those reported in mitochondria of Rous sarcoma virus-infected cells.
D000650:Amnion; D000818:Animals; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002474:Cell-Free System; D006801:Humans; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure*; D008325:Mammary Neoplasms, Experimental; D051379:Mice; D008809:Mice, Inbred C3H; D008928:Mitochondria / Q000648:ultrastructure*; D009858:Oncogenic Viruses; D012328:RNA Viruses