[Vitiligo, hepato-splenomegaly, and goitre after working with paratertiary butylphenol (author's transl)].
In three men vitiligo-like skin changes, enlargement of liver and spleen and diffuse goitre (grade II) with increased TSH secretion developed within one to two years of their having started work in a factory producing paratertiary butylphenol. These observations also tend to confirm the often discussed pathogenetic connection between vitiligo and thyroid disease.
D000328:Adult; D004781:Environmental Exposure; D005221:Fatigue / Q000139:chemically induced; D006042:Goiter / Q000139:chemically induced*; D006261:Headache / Q000139:chemically induced; D006529:Hepatomegaly / Q000139:chemically induced*; D006801:Humans; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced*; D010636:Phenols / Q000633:toxicity*; D013163:Splenomegaly / Q000139:chemically induced*; D014717:Vertigo / Q000139:chemically induced; D014820:Vitiligo / Q000139:chemically induced*
D010636:Phenols
Vitiligo, Hepatosplenopathie und Struma nach Arbeit mit paratertiärem Butylphenol