Nerve conduction studies in leprosy.
Motor and sensory nerve conduction studies have been performed on the peripheral nerves in the upper and lower limbs of 30 control subjects, and 36 subjects with leprosy from the Aboriginal population of the Northern Territory of Australia. Impairment of conduction was demonstrated in the vast majority of clinically abnormal nerves, and a large proportion of nerves which appeared clinically to be uninvolved. In a third group of subjects, abnormal conduction was demonstrated in a significant number of nerves which were considered to be clinically enlarged but in whom the diagnosis was initially in doubt. The majority of these patients were subsequently proven to have leprosy. It is concluded that nerve conduction studies are of considerable value in the diagnosis and management of leprosy.
D000200:Action Potentials; D000293:Adolescent; D000328:Adult; D001315:Australia; D005006:Ethnicity; D005071:Evoked Potentials; D006801:Humans; D007918:Leprosy / Q000175:diagnosis / Q000503:physiopathology*; D008475:Median Nerve / Q000503:physiopathology; D008875:Middle Aged; D009132:Muscles / Q000294:innervation; D009431:Neural Conduction; D011826:Radial Nerve / Q000503:physiopathology; D013497:Sural Nerve / Q000503:physiopathology; D013979:Tibial Nerve / Q000503:physiopathology; D014459:Ulnar Nerve / Q000503:physiopathology