Caffeine-mediated changes of sex ratio in Chinese hamsters, Cricetulus griseus.
Sixty 6- to 10-week-old male Chinese hamsters were assigned to two groups. In one, the animals were untreated and in the other, they were treated with 0.02 g caffeine/100 ml water orally for 60 days. The sex ratio of the resulting litters showed a significant (P smaller than 0.025) skewing towards females (61.4%) when compared to that of the controls (49.2%).
D000284:Administration, Oral; D000818:Animals; D002110:Caffeine / Q000008:administration & dosage / Q000494:pharmacology*; D006224:Cricetinae; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D012732:Sex Determination Analysis / Q000187:drug effects*; D012744:Sex Ratio
D002110:Caffeine