Effect of anti-obesity drugs on lipase activity in vitro.
Chlorphentermine, fenfluramine and dexamphetamine have a pronounced stimulating effect on lipolysis as determined by the action of mouse pancreas lipase on the dilauric (didodecanoic) acid ester of fluorescein. Diethylpropion and phendimetrazine have a comparatively minor effect.
D000818:Animals; D001067:Appetite Depressants / Q000494:pharmacology*; D066298:In Vitro Techniques; D008049:Lipase / Q000378:metabolism*; D051379:Mice; D010179:Pancreas / Q000201:enzymology; D013268:Stimulation, Chemical; D013644:Tartrates / Q000494:pharmacology
D001067:Appetite Depressants; D013644:Tartrates; D008049:Lipase