Platelet monoamine oxidase in children with infantile autism.
Platelet monoamine oxidase activity was measured in 9 autistic subjects and 9 controls. There were no significant differences in the rates of metabolism of 5-hydroxytryptamine, dopamine or tyramine between the two groups, although the rate of metabolism of tyramine was more rapid than 5-hydroxytryptamine or dopamine within each group. It is concluded that the data presented do not support the view that measurement of platelet monoamine oxidase can be used as a biochemical index to aid in the clinical diagnosis of infantile autism.
D000293:Adolescent; D000328:Adult; D001321:Autistic Disorder / Q000097:blood / Q000201:enzymology*; D001792:Blood Platelets / Q000201:enzymology*; D002648:Child; D004298:Dopamine / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008995:Monoamine Oxidase / Q000097:blood*; D012701:Serotonin / Q000097:blood; D014439:Tyramine / Q000097:blood
D012701:Serotonin; D008995:Monoamine Oxidase; D004298:Dopamine; D014439:Tyramine