Prognostic factors in endometrial carcinoma.
An analysis of 78 patients with surgical stage 1 adenocarcinoma of the endometrium reveals that several factors influence the prognosis. Differentiation of the tumour, and the depth of the uterine cavity, play a role, but a depth of 10 cm seems to be of greater assistance in prognostication than one of 8 cm. The menopausal state is very important, since not one patient who was less than 5 years postmenopausal died from carcinoma, and the majority who developed metastases were between 5 and 10 years postmenopausal. Prognosis did seem to be dependent on age, since the group aged between 60 and 70 years had the worst prognosis. Crude survival figures are useless for determining prognostic factors, and an analysis of patients dying from carcinoma must be made. That definite factors besides the method of treatment affect the survival of patients, makes it virtually impossible to make an accurate comparison of survival figures in different series.
D000230:Adenocarcinoma / Q000401:mortality* / Q000473:pathology; D000367:Age Factors; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D008593:Menopause; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011379:Prognosis; D014594:Uterine Neoplasms / Q000401:mortality* / Q000473:pathology; D014599:Uterus / Q000473:pathology