The syndrome of increased intracranial pressure without localizing signs: a reappraisal.
One hundred adult patients with headache, papilledema, and no localizing signs were evaluated prospectively and followed for up to 54 months. No patient with this syndrome who had a normal mental status, negative brain scan, and normal electroencephalogram was found subsequently to harbor a mass lesion. Benign intracranial hypertension was the final diagnosis in 71 percent of the patients studied. Lumbar puncture was a safe and helpful diagnostic procedure, and in no case was subsequent neurologic deterioration noted.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis*; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis; D003244:Consciousness Disorders / Q000209:etiology; D003937:Diagnosis, Differential; D004453:Echoencephalography; D004569:Electroencephalography; D005260:Female; D005947:Glucose / Q000134:cerebrospinal fluid; D006261:Headache / Q000209:etiology; D006801:Humans; D007427:Intracranial Pressure; D008297:Male; D008875:Middle Aged; D010211:Papilledema / Q000209:etiology; D011559:Pseudotumor Cerebri / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis*; D011877:Radionuclide Imaging; D012737:Sex Factors; D014786:Vision Disorders / Q000209:etiology; D014839:Vomiting / Q000209:etiology
D002556:Cerebrospinal Fluid Proteins; D005947:Glucose