Human pulmonary adiospiromycosis.
Emmonsia crescens, a fungus that causes granulomatous pulmonary adiospiromycosis, is an uncommon human pathogen. Histopathologic and ultrastructural evaluation of a new case of human adiospiromycosis from Guatemaia showed pulmonary granulomatosis in respose  to the inhaled spores of the fungus. The wall of each spore consisted of three zones. A fenestrated layer was clearly demonstrated within the middle zone. Neither budding nor endosporulation was detected. Our findings support the pathogenetic view that E crescens produces local changes by progressive enlargement of the inhaled spores and surrounding granulomas. Characteristically, the fungus does not propagate or disseminate within the lung
D000328:Adult; D001706:Biopsy; D002177:Candidiasis / Q000473:pathology*; D006099:Granuloma / Q000473:pathology; D006801:Humans; D008172:Lung Diseases, Fungal / Q000473:pathology*; D008297:Male; D008854:Microscopy, Electron; D003904:Mitosporic Fungi / Q000648:ultrastructure; D011650:Pulmonary Alveoli / Q000382:microbiology / Q000648:ultrastructure; D013172:Spores, Fungal / Q000648:ultrastructure