[Digitalization for acute myocardial infarction: haemodynamic changes in patients with heart failure at rest (author's transl)].
Haemodynamic changes after intravenous administration of 0.4 mg beta-methyldigoxin or 0.4 mg digoxin daily were measured on the first to fourth day in 42 patients in heart failure after onset of transmural myocardial infarction. Regular reduction in filling pressure and increased stroke volume while arterial blood pressure remained unaltered pointed to improved contractility. Digitalization in the first few days after infarction achieved sustained tendency towards improved haemodynamics. It is concluded that early digitalization is indicated in patients with acute myocardial infarction if there are signs of heart failure.
D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002302:Cardiac Output; D004077:Digoxin / Q000031:analogs & derivatives / Q000627:therapeutic use*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy*; D013997:Time Factors
D004077:Digoxin
Digitalis bei akutem Herzinfarkt. Hämodynamik bei Patienten mit Ruheinsuffizienz