A new antibiotic victomycin (XK 49-1-B-2). II. Isolation, purification and physicochemical and biological properties.
A new antibiotic, victomycin, is active against a variety of Gram-positive and Gram-negative bacteria, and also has in vivo activity against solid Sarcoma 180 and Ehrlich ascites carcinoma. It belongs to the phleomycin-bleomycin group of antibiotics and has been differentiated from all known phleomycins and bleomycins by its physicochemical properties and thin-layer chromatograms.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy; D002854:Chromatography, Paper; D002855:Chromatography, Thin Layer; D004355:Drug Stability; D051379:Mice; D008826:Microbial Sensitivity Tests; D012510:Sarcoma 180 / Q000188:drug therapy; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic