[Functional state of the testis after the use of certain antibiotics and nitrofuran preparations].
The functional state of the testis due to the effect of antibacterial therapy was studied in 50 patients suffering from chronic inflammatory diseases of the urinary-genital system and treated with neomycin, streptomycin, tetracycline, furadonin and furagin. It was shown that the above nitrofurans and neomycin had a negative effect on the testis function lowering the number of the spermatozoa in 1 ml and the whole ejaculate and their mobility. Contrary to it tetracycline therapy had no significant effect on the spermatozoa number, while the use of streptomycin was accompanied by a certain tendency to an increase in their number. The data were to some extent in certain accordance with the results of the experimental studies.
D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002908:Chronic Disease; D003864:Depression, Chemical; D006801:Humans; D006827:Hydantoins / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009355:Neomycin / Q000009:adverse effects; D009581:Nitrofurans / Q000009:adverse effects*; D009582:Nitrofurantoin / Q000009:adverse effects*; D011472:Prostatitis / Q000188:drug therapy; D013081:Sperm Motility / Q000187:drug effects; D013091:Spermatogenesis / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects; D013307:Streptomycin / Q000009:adverse effects; D013737:Testis / Q000187:drug effects*; D013752:Tetracycline / Q000009:adverse effects; D013997:Time Factors; D014526:Urethritis / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D006827:Hydantoins; D009581:Nitrofurans; D009582:Nitrofurantoin; D013752:Tetracycline; D009355:Neomycin; D013307:Streptomycin
Funktsional'noe sostoianiee iaichka pri primenenii nekotorykh antibiotikov i notrofuranovykh preparatov