The effect of fospirate on Echinococcus granulosus and Taenia hydatigena infections in dogs.
Trials with fospirate carried out with 170 dogs infected with either Echinococcus granulosus or Taenia hydatigena indicated that a dose rate of 40 mg/kg given on three occasions and 10 mg/kg given on one occasion eliminated each species, respectively. Increasing the dose rat substantially above 40 mg/kg did not reduce the number of treatments required to eliminate all hydatid organisms. Vomiting was observed in some dogs.
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004443:Echinococcosis / Q000188:drug therapy / Q000662:veterinary*; D005260:Female; D008297:Male; D009943:Organophosphorus Compounds / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*; D013622:Taeniasis / Q000188:drug therapy / Q000662:veterinary*
D000871:Anthelmintics; D009943:Organophosphorus Compounds; D011725:Pyridines; C010964:fospirate