Calcitonin: a general survey.
Since the initial discovery of calcitonin, a considerable amount of information has been obtained concerning structure, function, secretion, and effects of the hormone from a number of species. The purpose of the present report is to review the studies of structure and function, the factors that influence secretion and synthesis, and the effects and mechanism of action of calcitonin. The clinical uses of the hormone and syndromes of calcitonin excess are discu,sed.
D000595:Amino Acid Sequence; D000818:Animals; D001842:Bone and Bones / Q000187:drug effects; D002116:Calcitonin / Q000096:biosynthesis / Q000378:metabolism / Q000494:pharmacology / Q000502:physiology; D002118:Calcium / Q000097:blood; D050260:Carbohydrate Metabolism; D002277:Carcinoma / Q000188:drug therapy; D055598:Chemical Phenomena; D002621:Chemistry; D004064:Digestive System / Q000187:drug effects; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy; D007668:Kidney / Q000187:drug effects; D050356:Lipid Metabolism; D010001:Osteitis Deformans / Q000188:drug therapy; D010024:Osteoporosis / Q000188:drug therapy; D012474:Salmon; D012756:Sheep; D013045:Species Specificity; D013329:Structure-Activity Relationship; D013552:Swine; D013961:Thyroid Gland / Q000187:drug effects; D013964:Thyroid Neoplasms / Q000188:drug therapy
D002116:Calcitonin; D002118:Calcium