Acute cardiomyopathy with rhabdomyolysis in chronic alcoholism.
Of five chronic alcoholics with acute skeletal muscle necrosis (rhabdomyolysis) three developed acute heart failure with disturbances of rhythm and conduction. Symptoms came on abruptly after a period of intensified drinking. Myocardial infarction, thiamine deficiency, and cobalt intoxication were excluded. Probably the whole spectrum of muscle disease in chronic alcoholism may be commoner than has been suspected.
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000437:Alcoholism / Q000150:complications*; D001145:Arrhythmias, Cardiac / Q000209:etiology; D001219:Aspartate Aminotransferases / Q000097:blood; D003402:Creatine Kinase / Q000097:blood; D006333:Heart Failure / Q000150:complications / Q000209:etiology*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000201:enzymology / Q000209:etiology*; D009212:Myoglobinuria / Q000209:etiology; D009336:Necrosis / Q000209:etiology; D012907:Smoking / Q000150:complications
D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D003402:Creatine Kinase