Systemic lupus erythematosus and spontaneously arising anticoagulants.
Of 36 patients with systemic lupus erythematosus, 3 were demonstrated to have an abnormality in their haemostatic mechanism. In 2 this was believed to be on the basis of an auto-antibody to the phospholipid of platelets in the prothrombin activator complex. In the third an inhibitor was directed against factor VIII.
D001323:Autoantibodies; D001778:Blood Coagulation Disorders / Q000209:etiology* / Q000276:immunology; D005169:Factor VIII / Q000276:immunology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology; D011516:Prothrombin / Q000276:immunology*
D001323:Autoantibodies; D011516:Prothrombin; D005169:Factor VIII