The effect of diethylstilbestrol on the rate of osseous repair, bone integrity, and plasma calcium in the adult avian.
The effect of diethylstilbestrol on healing experimental osseous defects in adult roosters was studied by means of I-125 photon absorptiometry. Although the two dose levels utilized in this study both resulted in elevated plasma calcium and lipid levels and significantly increased the mineral and organic fractions of femoral bone, diethylstilbestrol treatment over a six-week period had no effect on the rate or magnitude of mineralization in the repairing osseous defect.
D000042:Absorption; D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects*; D001842:Bone and Bones / Q000032:analysis; D002113:Calcification, Physiologic / Q000187:drug effects; D002118:Calcium / Q000032:analysis / Q000097:blood*; D002645:Chickens; D004054:Diethylstilbestrol / Q000494:pharmacology*; D004601:Elementary Particles; D005269:Femur; D008055:Lipids / Q000097:blood; D008297:Male; D010027:Osteotomy; D010758:Phosphorus / Q000032:analysis
D008055:Lipids; D010758:Phosphorus; D004054:Diethylstilbestrol; D002118:Calcium