Clinicopathologic case reports: Optic nerve head metastasis.
A case of tumor metastasis from carcinoma of the lung directly to the cribriform plate is described. Retina and optic nerve were involved, but there was no evidence of tumor invasion of the choroid. It is postulated that the original tumor embolus lodged in a cribriform branch of the arterial circle of Zinn or in the central retinal vessels.
D002294:Carcinoma, Squamous Cell; D005004:Ethmoid Bone; D005134:Eye Neoplasms / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009900:Optic Nerve / Q000473:pathology; D009901:Optic Nerve Diseases / Q000473:pathology*; D010524:Peripheral Nervous System Neoplasms; D012888:Skull Neoplasms