The transfer of glucose to steroids by chimpanzee liver microsomes.
Microsomal preparations from chimpanzee liver can transfer glucose from UDPglucose to the 17alpha-hydroxyl group of 17alpha-estradiol and of 17alpha-estradiol-3-glucuronide. A phenolic glucoside of estrone, but not of either 17alpha- or 17beta-estradiol is also formed. No formation of glucosides of  p-nitrophenol, or of diethylstilbestrol was demonstrated. The specificity of glucosyl transfer in the chimpanzee is not identical to that in either the human, the rabbit, or the sheep.
D000818:Animals; D004958:Estradiol / Q000378:metabolism; D004964:Estriol / Q000378:metabolism; D004967:Estrogens / Q000378:metabolism*; D004970:Estrone / Q000378:metabolism; D005260:Female; D005690:Galactose / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D005965:Glucuronates / Q000378:metabolism; D008862:Microsomes, Liver / Q000378:metabolism*; D002679:Pan troglodytes; D014532:Uridine Diphosphate Glucose / Q000378:metabolism
D004967:Estrogens; D005965:Glucuronates; D004970:Estrone; D004958:Estradiol; D004964:Estriol; D005947:Glucose; D014532:Uridine Diphosphate Glucose; D005690:Galactose