[Immunologic study of subacute infectious endocarditis through the search for circulating immune complexes. Preliminary results apropos of 13 cases].
The detection of circulating immune complexes by precipitation by polyethylene glycol represents a valuable technique of study in sub-acute bacterial endocarditis. In a series of 13 patients, this measurement was carried out, confirming the quasi-constant presence of circulating immune complexes in active S.B.E. This might be of diagnostic value in forms with negative blood culture and, further, make it possible, subsequently, to find the antigen responsible by dissociation of the circulating immune complexes.
D000328:Adult; D000936:Antigen-Antibody Complex; D000942:Antigens, Bacterial / Q000032:analysis; D001424:Bacterial Infections / Q000150:complications; D001485:Basement Membrane / Q000276:immunology; D011232:Chemical Precipitation; D003172:Complement C1; D003168:Complement Fixation Tests; D003450:Cryoglobulins / Q000032:analysis; D004698:Endocarditis, Subacute Bacterial / Q000150:complications / Q000276:immunology*; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications; D006801:Humans; D006942:Hypergammaglobulinemia / Q000209:etiology; D007075:Immunoglobulin M / Q000032:analysis; D007457:Iodine Radioisotopes; D007678:Kidney Glomerulus / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000276:immunology; D011092:Polyethylene Glycols; D012217:Rheumatoid Factor / Q000032:analysis
D000936:Antigen-Antibody Complex; D000942:Antigens, Bacterial; D003172:Complement C1; D003450:Cryoglobulins; D007075:Immunoglobulin M; D007457:Iodine Radioisotopes; D011092:Polyethylene Glycols; D012217:Rheumatoid Factor
Etude immunologique des endocardites infectieuses subaiguës par recherches de complexes immuns circulants. Résultats préliminaires à propos de 13 observations