[Effect of pregnancy on the biotransformation of aminophenazone].
During delivery there was found a prolongation of the halflife-time of Aminophenazon in comparison with a group of non-pregnant women. Thinlay-chromatography investigations of the metabolitspektrum show, that the cause of this fact is a changed biotransformation in pregnancy. The placental share in metabolism of Aminophenazon is very small. The influence of gestagens concerning the biotransformation is discussed.
D000632:Aminopyrine / Q000378:metabolism* / Q000652:urine; D001711:Biotransformation; D005260:Female; D006801:Humans; D010477:Perfusion; D010920:Placenta / Q000378:metabolism; D011247:Pregnancy
D000632:Aminopyrine
Auswirkung der Schwángerscháft áuf die Biotransformation von Aminophenazon