Lens fringe in homocystinuria.
The lens from a patient with homocystinuria was examined by scanning and transmission electron microscopy. A fringe of zonular remnants was found attached to the anterior lens capsule, and was observed to be composed of masses of short filaments in disarray, together with occasional bundles of normal-appearing zonular filaments. Although a pericapsular membrane (zonular lamella) was not observed, the remainder of the lens capsule and epithelium appeared unremarkable. The lens fringe of white zonular remnants may be characteristic, if not pathognomic, for homocystinuria.
D000293:Adolescent; D002648:Child; D005260:Female; D006712:Homocystinuria / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007908:Lens, Crystalline / Q000002:abnormalities* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning