[Vitamin E concentration in blood and tissues of growing pigs fed on varying DL-a-Tocopherylacetate supplements].
The concentration of tocopherols in blood serum, liver and adipose tissue of growing pigs with different vitamin E supply was estimated gas-chromatographically. The animals were fed with a practical diet, supplemented with 0, 5, 15, 25 and 95 ppm dl-alpha-tocopheryl acetate (groups I-V). Based on a naturally vitamin E content of 7.4 and 8.6 mg per kg of the diet the control animals (group I) showed very low tocopherol concentrations of 0.5 mug per ml serum and about 1 mug per g tissue. No clinical vitamin E-deficiency symptoms were observed. The increasing alpha-tocopherol supplements raised the vitamin E contents in a proportional rate, and with high vitamin E supplies the highest quantities of tocopherols were stored in the adipose tissue. When the alpha-tocopherol content in the diet was raised by 1 mg, the concentration in the serum increased by 0.033 mug per ml, in the liver by 0.094 and in the adipose tissue by 0.129 mug per g, respectively (gamma = 0.99). This increase in the concentrations was strongly linear and can be interpreted by constant rates of absorption and retention of alpha-tocopherol in the present investigation. The growth of the pigs was no influenced by the different alpha-tocopherol supplements.
D000273:Adipose Tissue / Q000378:metabolism*; D000818:Animals; D004032:Diet; D004305:Dose-Response Relationship, Drug; D005503:Food Additives; D008099:Liver / Q000378:metabolism*; D013268:Stimulation, Chemical; D013552:Swine; D014810:Vitamin E / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*
D005503:Food Additives; D014810:Vitamin E
Blut- und Gewebekonzentrationen an Vitamin E von wachsenden Schweinen bei unterschiedlichen DL-alpha-Tocopherylacetat-Zulagen