The influence of carathane and toxaphene on the activity of some enzymes in rat's tissues in the studies in vivo.
Administration of pesticides to the experimental animals bring changes in the activity of enzymes: 3.1.3.1. alkaline phosphatase (AP), 3.1.3.2. acid phosphatase (AcP), 1.4.1.2. glutamin dehydrogenase (GDH), 1.1.1.27. lactate dehydrogenase (LDH), 2.6.1.1. glutamic oxalacetic transaminase (GOT), and 2.6.1.2. glutamic pyruvic transaminase (GPT), determined in blood serum, liver, and kidneys. In the majority of cases these changes are statistically significant.
D000135:Acid Phosphatase / Q000097:blood / Q000378:metabolism*; D000410:Alanine Transaminase / Q000097:blood / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood / Q000378:metabolism*; D004140:Dinitrophenols / Q000494:pharmacology*; D005969:Glutamate Dehydrogenase / Q000097:blood / Q000378:metabolism*; D007306:Insecticides / Q000494:pharmacology*; D007668:Kidney / Q000201:enzymology; D007770:L-Lactate Dehydrogenase / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D008297:Male; D051381:Rats; D014112:Toxaphene / Q000494:pharmacology*
D004140:Dinitrophenols; D007306:Insecticides; D014112:Toxaphene; D007770:L-Lactate Dehydrogenase; D005969:Glutamate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase