Carcinoma of the bladder complicating cyclophosphamide therapy.
Two patients with cyclophosphamide induced cystitis and co-existent bladder tumour are described. Possible mechanisms for these associated diseases are discussed and the difficulty of diagnosing bladder tumour in patients with haemorrhagic cystitis is stressed.
D003520:Cyclophosphamide / Q000009:adverse effects* / Q000627:therapeutic use; D003556:Cystitis / Q000139:chemically induced*; D003558:Cystoscopy; D004359:Drug Therapy, Combination; D005260:Female; D006689:Hodgkin Disease / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008223:Lymphoma / Q000188:drug therapy; D008875:Middle Aged; D009362:Neoplasm Metastasis; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced* / Q000473:pathology
D007166:Immunosuppressive Agents; D003520:Cyclophosphamide