Diminished immune response in pregnant mice.
As pregnancy proceeded, humoral immune response to sheep red blood cells gradually decreased in a pregnant mouse. At the later stage of pregnancy, it showed significantly diminished immune response but it recovered immediately after delivery. The possibility was excluded by the hormone treatment that progesterone played in suppression of immune response in a pregnant mouse.
D000818:Animals; D000917:Antibody Formation; D005260:Female; D051379:Mice; D011247:Pregnancy; D011270:Pregnancy, Animal; D011374:Progesterone / Q000502:physiology
D011374:Progesterone