[Blood circulation in the cerebral cortex, reticular structure and hypothalamus in myocardial infarction in non-anesthetized animals].
The local cerebral blood flow and oxygen tension in the brain cortex, the reticular formation of the mesencephalon and the posterior hypothalamus were studied in chronic experiments in non-anesthetized rabbits with experimentally induced myocardial infarction. During the initial hours after the occlusion of the coronary artery a distinct reduction of the blood flow and oxygen tension was noted in the mentioned structures of the brain, against the background of an arterial pressure fall; in the subsequent days a varying dynamics of the re-establishment of the cerebral blood flow and arterial pressure was observed. It is suggested that in myocardial infarction not only the general hemodynamics undergoes certain changes, but the reserves of the autoregulation mechanisms of the cerebral blood flow get sharply reduced, resulting in brain tissue hypoxia and disorders in the regulation of cardiac activity and the peripheral vascular tone.
D000818:Animals; D001921:Brain / Q000098:blood supply*; D002540:Cerebral Cortex / Q000098:blood supply; D002560:Cerebrovascular Circulation; D006439:Hemodynamics; D007031:Hypothalamus / Q000098:blood supply; D002534:Hypoxia, Brain / Q000209:etiology; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology*; D011817:Rabbits; D012039:Regional Blood Flow; D012154:Reticular Formation / Q000098:blood supply
Krovoobrashchenie v kore golovnogo mozga, retikuliarnoĭ formatsii i gipotalamuse pri infarkte miokarda u nenarkotizirovannykh zhivotnykh