[Estimation of pathomorphological and histochemical changes in the liver of pigs in the course of edema disease of swine].
Post-mortem examinations concerned 16 pigs which had died of the oedema disease. A group of 8 healthy pigs were slaughtered at the Lublin abattoir and used as controls. All animals were subjected to detailed autopsy, and sections of the liver were taken for histological examination. The fixed material was cut into sections by the paraffin and refrigeration methods. To the routine staining with haematoxylin and eosin, colour reactions were added to reveal glycogen, simple fats and acid and alkaline phosphatase. The macro- and microscopic examinations demonstrated chronic, focal inflammation of the liver capsule connected with liver cirrhosis. Hyperaemia of the liver was noticed in all cases. A decrease of glycogen, associated with progressive fatty infiltration of the liver cells, was observed in the diseased pigs in contrast to the control group. An increase of the activity of hydrolytic enzymes and a positive reaction to cholesterol compounds are symptoms of progressive catabolic changes in the liver cells.
D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D001344:Autopsy / Q000662:veterinary; D004488:Edema Disease of Swine / Q000201:enzymology / Q000378:metabolism / Q000473:pathology*; D006651:Histocytochemistry; D008099:Liver / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D008112:Liver Glycogen / Q000032:analysis; D013552:Swine
D008112:Liver Glycogen; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase
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