Cytogenetic investigations on leucocytes of workers from a cadmium plant.
Chromosome analysis has been performed on workers from a cadmium plant who were exposed to fumes and dust of cadmium and lead. The 35 workers were classified, according to the type and duration of exposure, into a group (cadmium service) exposed to high levels of lead and cadmium in the absence of zinc (23 people) and a group of rolling-mill workers subjected mostly to zinc but also to lower levels of lead and cadmium (12 people). A higher yield of severe chromosome anomalies (chromatid exchange, disturbance of spiralization, chromosome translocation, ring and dicentric chromosomes) together with a total lower number of structural aberrations was observed in the cadmium workers when compared with the rolling-mill group.
D000328:Adult; D002104:Cadmium / Q000097:blood; D002842:Chromatids / Q000648:ultrastructure; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000032:analysis*; D004781:Environmental Exposure; D006801:Humans; D007621:Karyotyping; D007854:Lead / Q000097:blood; D007962:Leukocytes / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged; D008938:Mitosis; D013997:Time Factors; D014178:Translocation, Genetic / Q000187:drug effects; D015032:Zinc / Q000097:blood
D002104:Cadmium; D007854:Lead; D015032:Zinc