Progression of coronary artery disease in patients with stable angina pectoris. Arteriographic, ventriculographic and other correlation studies.
Left ventriculography and selective coronary angiography with determination of resting left ventricular end-diastolic pressures and ejection fraction have been carried out twice on 25 patients with stable angina pectoris. The interval between the two angiographic studies varied between 7 and 16 months (mean 12.3). Progression of obstruction amounting to occlusion was found in 4 of 73 arteries studied (5%). No new lesions occurred. Resting end-diastolic pressures before and after ventriculography did not change during the observation period. Values for ejection fraction were also unchanged, but there was a tendency for them to decrease in patients in whom this parameter had been abnormal at the first catheterization.
D000787:Angina Pectoris / Q000503:physiopathology*; D000790:Angiocardiography; D001794:Blood Pressure; D002302:Cardiac Output; D002932:Cineangiography; D017023:Coronary Angiography; D003327:Coronary Disease / Q000503:physiopathology; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors