A transducer probe for the detection of oestrogen effects on vaginal blood flow in sheep.
A simple prototype vaginal probe was designid for the electronic detection of oestrogen-induced blood flow changes by measuring thermal conductivity, tissue temperature, and light reflectance. The probe was tested in six castrate ewes. Treatment with oestradiol-17beta (1.0 mg iv) produced marked changes in thermal conductivity and temperature, but had no detectable effect on reflectance. The study demonstrates the feasibility of multiple-sensor electronic probes for non-invasive monitoring of peripheral oestrogen effects in vivo.
D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D008027:Light; D008722:Methods; D012039:Regional Blood Flow / Q000187:drug effects; D012756:Sheep; D013268:Stimulation, Chemical; D013814:Thermal Conductivity; D014159:Transducers; D014621:Vagina / Q000098:blood supply* / Q000187:drug effects
D004958:Estradiol