[Synthesis and biological activity of pyrido(2,3-e)-1,4-diazepine and of pyrido(2,3-b)(1,4)diazepine].
The Schmidt reaction on tetrahydro-1,8-naphthyridin-4-ones gave pyrido [2,3-e]-1,4-diazepines and pyrido[2,3-b][1,4]diazepines. The preliminary pharmacological screening of some of these compounds showed no appreciable activity.
D000935:Antifungal Agents; D001381:Azepines / Q000138:chemical synthesis* / Q000494:pharmacology; D002319:Cardiovascular System / Q000187:drug effects; D002490:Central Nervous System / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D004353:Drug Evaluation, Preclinical; D011725:Pyridines / Q000138:chemical synthesis / Q000494:pharmacology
D000935:Antifungal Agents; D001381:Azepines; D011725:Pyridines
Sintesi ed attivita biologica di pirido[2,3-e]-1,4-diazepine e di pirido[2,3-b][1,4]diazepine