[Effect of the stereoisomers of glutamic acid on the vital activity of auxotrophic mutant producers of lysine].
Studies of L, D and DL-forms of glutamic acid as the sole nitrogen source or as a supplement to the major nitrogen source--ammonium sulphate have demonstrated that in the first case all forms of glutamic acid are assimilated by auxotrophic mutants--lysine producers. However, the lysine synthesis was very low, when L-glutamic acid was used as the only nitrogen source. Glutamic acid at a concentration of 0.01 M applied as a supplement to the major source of nitrogen acted as a stimulator of lysine synthesis, slightly inhibiting biomass increment. That was true of every form of glutamic acid, especially of DL-glutamic acid.
D000645:Ammonium Sulfate / Q000378:metabolism; D001951:Brevibacterium / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D003470:Culture Media; D005827:Genetics, Microbial; D005947:Glucose / Q000378:metabolism; D005971:Glutamates / Q000494:pharmacology*; D008239:Lysine / Q000096:biosynthesis*; D008837:Micrococcus / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D008967:Molecular Biology; D009154:Mutation; D013237:Stereoisomerism; D013997:Time Factors
D003470:Culture Media; D005971:Glutamates; D005947:Glucose; D008239:Lysine; D000645:Ammonium Sulfate
Vliianie stereoizomerov glutaminovoĭ kisloty na zhiznedeiatel'-nost' auksotrofnykh mutantov--produtsentov lizina