[Relation between chemical structure of quinoxalines disubstituted at the 2,3-positions and the enzymatic detoxication activity in rat liver microsomes].
D000633:Aminopyrine N-Demethylase / Q000378:metabolism; D000814:Aniline Compounds; D000815:Aniline Hydroxylase / Q000378:metabolism; D000818:Animals; D001711:Biotransformation; D001835:Body Weight / Q000187:drug effects; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004247:DNA / Q000378:metabolism; D005260:Female; D066298:In Vitro Techniques; D008658:Inactivation, Metabolic; D008099:Liver / Q000187:drug effects; D008862:Microsomes, Liver / Q000201:enzymology* / Q000378:metabolism; D009575:Nitroanisole O-Demethylase / Q000378:metabolism; D009929:Organ Size / Q000187:drug effects; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D011810:Quinoxalines / Q000494:pharmacology*; D012313:RNA / Q000378:metabolism; D051381:Rats; D013329:Structure-Activity Relationship
D000814:Aniline Compounds; D011506:Proteins; D011810:Quinoxalines; D012313:RNA; D004247:DNA; D003577:Cytochrome P-450 Enzyme System; D009575:Nitroanisole O-Demethylase; D000815:Aniline Hydroxylase; D010089:Oxidoreductases, N-Demethylating; D000633:Aminopyrine N-Demethylase
Relations entre la structure chimique de quinoxalines disubstituees en positions 2,3 et les activites de detoxication enzymatique des microsomes hepatiques du rat