Quantitative cyto- and histochemical studies of the Deiter's nucleus and nodular cortex of cerebellum in rats exposed to weightlessness.
Spaceflight aboard the "Cosmos-605" artificial satellite during 22 d does not have a substantial effect upon the activity of enzymes involved in energy metabolism--lactate dehydrogenase and creatine kinase--in cytoplasm of the giant neurons of the dorsocaudal part of the Deiters' nucleus and cortex layers of the cerebellar nodulus in rats. At the same time, on the second postflight day, in the molecular layer of cerebellar nodulus in rats flown for 22 d in space, some increase in lipid content was noted, probably connected with quantitative or qualitative changes in afferent impulses from the vestibular apparatus to the nodulus. On the 27th postflight day, lipid content in the molecular layer returned to the level observed in rats during ground-based experiments.
D000818:Animals; D002531:Cerebellum / Q000032:analysis* / Q000166:cytology / Q000201:enzymology; D003402:Creatine Kinase / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D050356:Lipid Metabolism; D051381:Rats; D013026:Space Flight; D014726:Vestibular Nuclei / Q000032:analysis*; D003689:Vestibular Nucleus, Lateral / Q000032:analysis* / Q000166:cytology / Q000201:enzymology; D014893:Weightlessness
D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase