Etiological factors of the Stevens-Johnson syndrome.
Etiologic factors of the Stevens-Johnson syndrome, both drug-related and nondrug-related, are discussed. A description of the Stevens-Johnson syndrome as a symptom complex is presented. Available literature is reviewed and critiqued as to its contribution in helping to define the role of drugs as specific etiologic factors in the syndrome. A patient case history is presented to demonstrate the difficulty of determining the causative agent for the syndrome, and to emphasize the need for a complete drug history before specific agents are implicated. The need for caution and discretion in reporting and implicating agents without the availability of a complete patient history is discussed.
D000328:Adult; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D008297:Male; D013262:Stevens-Johnson Syndrome / Q000209:etiology*; D013449:Sulfonamides / Q000009:adverse effects; D014481:United States; D014486:United States Food and Drug Administration
D013449:Sulfonamides