The effect of pentazocine on PHA-stimulated human lymphocyte transformation.
The effect of pentazocine on lymphocyte transformation induced by PHA was studied in vitro by observing the incorporation of 3H-thymidine into nucleic acid of the lymphocytes. Pentazocine in therapeutic concentrations was shown to inhibit lymphocyte transformation.
D000328:Adult; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007165:Immunosuppression Therapy; D066298:In Vitro Techniques; D037102:Lectins / Q000037:antagonists & inhibitors; D008213:Lymphocyte Activation / Q000187:drug effects*; D010423:Pentazocine / Q000494:pharmacology*
D037102:Lectins; D010423:Pentazocine