Germ-cell malignant tumours in father and son.
Germ-cell malignant tumours occurred in a man and his son. The father, who had a teratoma of the right testicle removed 24 years ago, is presently alive and well. The son, who had a choriocarcinoma presenting as an abdominal mass, possibly originating in the testicle, died within 7 months of the diagnosis with metastases in the lungs, liver and retroperitoneum. This report documents the third such case of germ-cell neoplasms occurring in father and son.
D000328:Adult; D002822:Choriocarcinoma / Q000235:genetics*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology; D008297:Male; D009362:Neoplasm Metastasis; D013724:Teratoma / Q000235:genetics* / Q000473:pathology; D013736:Testicular Neoplasms / Q000235:genetics* / Q000473:pathology