The effect of transfer factor on the in vitro migration of tuberculin stimulated white cells from sarcoid and normal subjects.
In the mixed leukocyte migration test, white cells from Mantoux positive and Mantoux negative individuals and from patients with sarcoidosis responded similarly to tuberculin, there being no significant difference in the migration index of the three groups. The cells from patients with sarcoidosis, however, showed a depressed response to phytohaemagglutinin. Transfer factor prepared from an individual with a very positive Mantoux reaction did not have any significant effect on the migration index when added to the white cells from sarcoid patients either in the presence or absence of tuberculin.
D000328:Adult; D000368:Aged; D002464:Cell Migration Inhibition; D006801:Humans; D066298:In Vitro Techniques; D037102:Lectins / Q000494:pharmacology; D007962:Leukocytes / Q000276:immunology; D008875:Middle Aged; D012507:Sarcoidosis / Q000276:immunology*; D014165:Transfer Factor / Q000494:pharmacology*; D014373:Tuberculin / Q000276:immunology*
D037102:Lectins; D014165:Transfer Factor; D014373:Tuberculin