[Experimental study of manganese chloride toxicity].
In experiments with rabbits is shown weak toxic action of managanese chloride (0,5 and 5 mg/kg intravenously for 2 months) on the organism of animals. The blood managanese level rose only when the element was introduced in a large dose. The ascorbic acid content in the supprarenals diminished. At the site of the preparation administration (muscles) were in evidence manifestations of irritation (necrosis with regeneration), which disappeared 2 weeks after abolishment of the preparation.
D000311:Adrenal Glands / Q000187:drug effects; D000818:Animals; D001773:Blood Cells / Q000187:drug effects; D001786:Blood Glucose / Q000032:analysis; D004305:Dose-Response Relationship, Drug; D007928:Lethal Dose 50; D008345:Manganese / Q000097:blood; D020149:Manganese Poisoning; D051379:Mice; D009132:Muscles / Q000187:drug effects; D009584:Nitrogen / Q000097:blood; D011817:Rabbits; D051381:Rats; D012867:Skin / Q000187:drug effects; D013997:Time Factors
D001786:Blood Glucose; D008345:Manganese; D009584:Nitrogen
Izuchenie toksichnosti khloristogo margantsa v éksperimente