[Changes in the protein composition of the synaptic structures of the brain of rats in tetanus intoxication].
As shown by the method of electrophoresis on polyacrylamide gel, the number of proteins with low electrophoretic mobility proved to be increased in the triton extract fractions of synaptic structures isolated from spinal cord of rats with local tetanus; no changes in the protein spectrum were revealed in the dodecyl-sulphate extract. In vitro tetanus toxin stimulated the lysin-H3 incorporation into the total proteins of synaptosomes of rat brain cortex.
D000818:Animals; D001921:Brain / Q000187:drug effects; D001923:Brain Chemistry; D008239:Lysine / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000032:analysis; D011506:Proteins / Q000378:metabolism*; D051381:Rats; D013116:Spinal Cord / Q000378:metabolism; D013569:Synapses / Q000187:drug effects / Q000378:metabolism*; D013742:Tetanus / Q000378:metabolism*; D013744:Tetanus Toxin
D009419:Nerve Tissue Proteins; D011506:Proteins; D013744:Tetanus Toxin; D008239:Lysine
Izmeneniia belkovogo sostava sinapticheskikh struktur mozga krys pri stolbniachnoĭ intoksikatsii