Hormone-dependent Polyploidy in the glandula orbitalis externa and glandula infraorbitalis of animals of different age.
The Glandula orbitalis externa and Glandular infraorbitalis of castrated and intact male rats were examined by morphological, chemical and cytophotometric methods after one, three, six and twelve months of life. Whereas qualitative changes in the cell nucleus (e.g. nuclear vacuolation, nuclear fusion) and cytoplasm (cytoplasmic vacuolation) can be detectedin the sexually mature control animals, these did not occur in the castrated male rats. An increase the percentage of higher ploid gland cell nuclei occurred only in the intact control animals. The possible cause this clearly hormone-dependent polyploidy is discussed.
D000367:Age Factors; D000818:Animals; D002369:Castration; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D007765:Lacrimal Apparatus / Q000473:pathology*; D008297:Male; D010783:Photometry; D011123:Polyploidy; D051381:Rats