Lymphocyte reactivity to influenza virus in man.
Dermal delayed hypersensitivity and in vitro lymphocyte reactivity, both to purified influenza antigens, have been observed in man. A correlation between these two indices of delayed hypersensitivity was found in subjects without known recent exposure to the virus, but neither correlated with levels of circulating haemagglutination-inhibiting (HAI) antibody. Results suggest that in man immunological sensitization of lymphocytes to influenza virus antigen is long-lived.
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral; D003176:Complement C3; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D066298:In Vitro Techniques; D009980:Influenza A virus / Q000276:immunology; D037102:Lectins; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D009975:Orthomyxoviridae / Q000276:immunology*; D012882:Skin Tests
D000914:Antibodies, Viral; D000956:Antigens, Viral; D003176:Complement C3; D037102:Lectins