[Pharmacodynamics, site and mechanism of action of silymarin, the antihepatoxic principle from Silybum mar. (L) Gaertn. 1. Acute toxicology or tolerance, general and specific (liver-) pharmacology].
D000410:Alanine Transaminase / Q000097:blood; D000429:Alcohol Oxidoreductases / Q000097:blood; D000546:Amanitins / Q000037:antagonists & inhibitors; D000779:Anesthetics, Local / Q000494:pharmacology; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001831:Body Temperature / Q000187:drug effects; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy*; D004285:Dogs; D005260:Female; D005419:Flavonoids / Q000627:therapeutic use*; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D010590:Phalloidine / Q000037:antagonists & inhibitors; D011817:Rabbits; D051381:Rats; D012838:Silymarin / Q000494:pharmacology / Q000627:therapeutic use* / Q000633:toxicity; D013012:Sorbitol; D013997:Time Factors; D014655:Vascular Resistance / Q000187:drug effects
D000546:Amanitins; D000779:Anesthetics, Local; D005419:Flavonoids; D012838:Silymarin; D010590:Phalloidine; D013012:Sorbitol; D000429:Alcohol Oxidoreductases; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
Untersuchungen zu Pharmakodynamik, Angriffspunkt und Wirkungsmechanismus von Silymarin, dem antihepatotoxischen Prinzip aus Silybum mar. (L). Gaertn. 1. Mitteilung: Akute Toxikologie bzw. Verträglichkeit, allgemeine und spezielle (Leber-)Pharmakologie