Human embryo (12 mm) with mesohydronephrosis and ureterohydronephrosis.
This report describes a human embryo with a length of 12 mm (horizon XVII Streeterm 35 +/- 1 day old), in which the following malformations appear: Dilation on both sides of the Wolffian ducts, and the more caudal mesonephritic glomerules (mesohydronephrosis). Dilatation of both ureters and renal pelvis (uretero-hydronephrosis). These malformations are the result of the accumulation of liquid secreted by the mesonephros in a cloaca which is dilated, unwalled and blocked by an epithelial plug which is continuous with the cloacal membrane.
D000015:Abnormalities, Multiple / Q000473:pathology; D004622:Embryo, Mammalian; D006801:Humans; D006869:Hydronephrosis / Q000196:embryology* / Q000473:pathology; D008650:Mesonephros / Q000473:pathology; D014513:Ureter / Q000002:abnormalities* / Q000473:pathology