Testing the Mendelian segregation ratio under incomplete ascertainment.
The properties of a test, suggested by HALDANE [1938], for a Mendelian segregation ratio of 0.25 when ascertainment is incomplete are investigated. The error rates associated with this procedure show the weakness of this specific test. An alternative test based on a chi2 statistic is illustrated with the data on human albinism originally analyzed by HALDANE [1938].
D000417:Albinism / Q000235:genetics; D003201:Computers; D005826:Genetics, Medical; D006801:Humans; D008722:Methods; D010375:Pedigree; D011336:Probability; D013223:Statistics as Topic