Sensorimotor responsiveness in rats with unilateral superior collicular and amygdaloid lesions.
Large unilateral lesions of superior colliculus, but not amygdala, result in strong ipsiversive progression tendencies and permanent neglects of visual, auditory, and whisker-touch stimuli presented on the contralateral side of the body. Combined collicular-amygdaloid lesions also yield circling behaviors and multimodal neglects that are completely independent of the order or laterality of the amygdaloid lesion. Rats with colliculectomy either neglect or else turn away from pinches of the contralateral ear and forepaw. Subjects with combined lesions display more crossed orientations, and this tendency is greatly potentiated by ipsilateral lesion placement. The nature and time course of the crossed response in rats with sensory neglects is reminiscent of the clinical syndrome described as alloaesthesia or as contralateral sensory displacement.
D000679:Amygdala / Q000502:physiology*; D000818:Animals; D001307:Auditory Perception / Q000502:physiology; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D009949:Orientation / Q000502:physiology; D010465:Perception / Q000502:physiology*; D051381:Rats; D013477:Superior Colliculi / Q000502:physiology*; D014110:Touch / Q000502:physiology; D014796:Visual Perception / Q000502:physiology