The effect of some amine oxides and disulphide compounds on the activity of acetylcholinesterase.
Three amine oxides, two aliphatic and one aromatic, and 2,2'-dithiodipyridine were found to be weak reversible inhibitors of acetylcholinesterase. 5,5'-Dithiobis-(2-nitro-benzoic acid) had no effect on the enzyme under the conditions of the Ellman spectrophotometric assay.
D000110:Acetylcholinesterase / Q000378:metabolism*; D000588:Amines / Q000494:pharmacology*; D000818:Animals; D002417:Cattle; D002800:Cholinesterase Inhibitors; D004220:Disulfides / Q000494:pharmacology*; D004228:Dithionitrobenzoic Acid / Q000494:pharmacology; D004524:Eels; D004912:Erythrocytes / Q000201:enzymology; D007700:Kinetics; D010087:Oxides / Q000494:pharmacology*
D000588:Amines; D002800:Cholinesterase Inhibitors; D004220:Disulfides; D010087:Oxides; D004228:Dithionitrobenzoic Acid; D000110:Acetylcholinesterase