Enhancing fluidity of concentrated antacid suspensions.
Highly concentrated antacid suspension can by fluidized by adding a colloidal polyelectrolyte to alter the charge on antacid particles from positive to negative. A deflocculated state is assumed to exist in such preparations, as supported by electrophoretic and viscometric analyses. When viscosity is directly correlated with the zota-potential, viscometry becomes particularly useful in confirming that the suspension has been maximally fluidized.
D000536:Aluminum Hydroxide; D000863:Antacids; D002351:Carrageenan; D005427:Flocculation; D010316:Particle Size; D013535:Suspensions; D013678:Technology, Pharmaceutical; D014783:Viscosity
D000863:Antacids; D013535:Suspensions; D000536:Aluminum Hydroxide; D002351:Carrageenan