[Change in hemoglobin mass during prolonged hypokinesia].
The total hemoglobin mass was measured by the carbon monoxide method in 33 male test subjects, 21 of whom were exposed to 30-day bed rest and 6 of whom were exposed to 100-day bed rest. The hypokinetic test subjects showed a decrease in hemoglobin mass by 11-24%. During readaptation the test subjects who had a noticeable reduction of hemoglobin displayed a 2.7-fold increase of the reticulocyte count. It is suggested that the gravity decrease during bed rest and antiorthostatic hypokinesia results in a reduced rate of hemoglobin synthesis in bone marrow.
D000328:Adult; D004906:Erythrocyte Count; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D007103:Immobilization; D008297:Male; D012156:Reticulocytes; D013997:Time Factors
D006454:Hemoglobins
Izmenenie massy gemoglobina pri dlitel'noĭ gipokinezii