title: Globin messenger sequences in nuclear ribonucleoprotein particles of avian erythroblasts.
abstract: Nuclear ribonucleoprotein particles were isolated from chick erythroblast nuclei. The particles were found to sediment as heterogeneous material. The major fraction of the rapidly synthesized RNP sedimented at 30 S, whereas the nuclei were found to contain a major, apparently more stable, RNP component sedimenting at about 40 S. The RNA isolated from the RNP particles was assayed for globin messenger activity in a wheat germ cell-free system. RNP sedimenting at relatively low S values (approx. 15 S) as well as RNP-particles of larger size code for globin. In addition to globin, the RNA of the particles codes also for other, not yet identified, proteins.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002467:Cell Nucleus / Q000032:analysis*; D002645:Chickens; D004912:Erythrocytes / Q000032:analysis*; D005914:Globins / Q000096:biosynthesis*; D009698:Nucleoproteins / Q000097:blood*; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000032:analysis / Q000378:metabolism; D012261:Ribonucleoproteins / Q000032:analysis / Q000097:blood*
chemical_list: D009698:Nucleoproteins; D012333:RNA, Messenger; D012261:Ribonucleoproteins; D005914:Globins