Distribution and behaviour of isoselenouronium salts in the body. IV. 2-Aminoselenoazoline.
The time dependence of the distribution of 2-aminoselenoazoline-75Se in the organism of rats and mice was followed. By comparison of the results obtained with the previous study of radioprotective properties of this compound, its efficiency was shown to be dependent on the actual concentration in tissues.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D007550:Isothiuronium / Q000031:analogs & derivatives* / Q000378:metabolism; D007700:Kinetics; D008297:Male; D051379:Mice; D016566:Organoselenium Compounds; D011758:Pyrroles; D011837:Radiation-Protective Agents / Q000378:metabolism*; D011868:Radioisotopes; D051381:Rats; D012643:Selenium; D013890:Thiourea / Q000031:analogs & derivatives*
D016566:Organoselenium Compounds; D011758:Pyrroles; D011837:Radiation-Protective Agents; D011868:Radioisotopes; C011652:2-aminoselenoazoline; D007550:Isothiuronium; D013890:Thiourea; D012643:Selenium