title: The effect of isolated perfusion on limb circulation in peripheral arterial occlusion.
abstract: The effects of isolated limb perfusion were studied in 12 patients suffering from peripheral arterial occlusion. The hemodynamic investigations show that the vascular resistance decreases considerably during isolated limb perfusion. After administration of a vasodilator cocktail, added to the perfusion, the vascular resistance continues to decrease. Angiographic records, made before, during and after the perfusion, suggest that the calibre of the collateral vessels increases significantly and besides new collaterals can also be observed. The mechanism of the effects of isolated hyperbaric limb perfusion and its clinical value are discussed.
mesh_terms: D000328:Adult; D001157:Arterial Occlusive Diseases / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D001794:Blood Pressure; D003097:Collateral Circulation; D005069:Evaluation Studies as Topic; D006801:Humans; D006874:Hydrostatic Pressure; D007866:Leg / Q000098:blood supply*; D008875:Middle Aged; D010477:Perfusion / Q000379:methods*; D012039:Regional Blood Flow; D014655:Vascular Resistance; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D014665:Vasodilator Agents