title: [Utilization of serological methods in the retrospective diagnosis of cholera and in detecting vibrion carriers].
abstract: Sensitivity and specificity of the three serological methods were studied comparatively: the vibriocidal test, the reaction of bacterial agglutination and of indirect hemagglutination, with the use of erythrocytes sensitized with the vibrio lyzate, cholera species O-antigen and cholerogen. Investigations were conducted with the blood sera of cholera patients, vibrio carriers and contacts. Vibriocidal test proved to be the most sensitive; its data correlated with the results of bacterial agglutination and indirect hemagglutination with erythrocytes, sensitized with the lysate of the vibrios and the cholera O-antigen. None of the used serological methods provided a 100% coincidence with the results of bacteriological analysis. The frequency of detection of anticholera antibodies decreased in the following order: cholera patients, vibrio carriers, contacts.
mesh_terms: D000372:Agglutination Tests; D000907:Antibodies, Bacterial / Q000032:analysis; D002353:Carrier State / Q000175:diagnosis* / Q000276:immunology; D002771:Cholera / Q000175:diagnosis* / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D006386:Hemagglutination Tests; D006801:Humans; D012189:Retrospective Studies; D012698:Serologic Tests / Q000379:methods*; D013997:Time Factors; D014734:Vibrio cholerae / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial
vernacular_title: K voprosu ob ispol'zovanii serologicheskikh metodov v retrospektivnoĭ diagnostike kholery i pri vyiavlenii vibriononositeleĭ