title: [Features of cerebrovascular disorders in children with beta-thalassemia major].
abstract: In 42 patients with major beta-thalassemia the author studied the traits of cerebral vascular disorders with a correlation of clinical and REG data. In 5 cases the pathomorphology of different areas of the CNS was studied. In most of the cases there were transitory disorders of the brain circulation with transient neurological symptomatology. Acute strokes with stable focal disorders were encountered less frequently. Cerebral vascular disorders were more expressed in children from 6 to 12 years during hemolytical crises and in the terminal stage of the disease. REG data indicating changes of the cerebral hemodynamics testify to the compensatory vascular reaction which is necessary for the preservation of the functional capability of the brain in conditions of cerebral hypoxia.
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010100:Oxygen / Q000097:blood; D010992:Plethysmography, Impedance; D013789:Thalassemia / Q000097:blood / Q000150:complications* / Q000473:pathology
chemical_list: D010100:Oxygen
vernacular_title: Osobennosti tserebral'nykh sosudistykh narusheniĭ u deteĭ, bol'nykh bol'shoĭ beta-talassemieĭ