[Specific and nonspecific factors that influence the transduction of genetic determinants for penicillinase activity and pathogenicity in Staphylococcus aureus. III. The prevention of the transduction of penicillinase determinants by acridine derivatives].
In comparing the antitransducing activity of the acridine derivatives there was revealed a relationship between their chemical structure (the degree of substitution of position 9), the capacity to depress the lytic activity of staphylophages and the action in respect to the transducing particles of the donor lysate.
D000166:Acridines / Q000494:pharmacology*; D001433:Bacteriolysis; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D005796:Genes / Q000187:drug effects; D010405:Penicillinase / Q000378:metabolism*; D011370:Proflavine / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000201:enzymology / Q000472:pathogenicity*; D014161:Transduction, Genetic / Q000187:drug effects*
D000166:Acridines; D011370:Proflavine; D010405:Penicillinase
Spetsificheskie i nespetsificheskie faktory, vliiaiushchie na transduktsiiu geneticheskikh determinantov penitsillinaznoĭ aktivnosti i patogennosti u zolotistogo stafilokokka. Soobshchenie III. Predotvrashchenie proizvodnymi akridina transduktsii penitsillinaznykh determinantov