Microbial transformation of aspidospermine.
Thirty actinomycetes were isolated from soil samples and screened for their ability to modify the structure of aspidospermine. One actinomycete culture converted aspidospermine into O-demethylaspidospermine but failed to modify N-deacetylaspidospermine, N-ethyl-N-deacetylaspidospermine, 7-methoxyindole, and 7-methoxytryptophan.
D000192:Actinomycetales / Q000378:metabolism*; D005285:Fermentation; D008745:Methylation; D013096:Spermine / Q000031:analogs & derivatives* / Q000378:metabolism; D013997:Time Factors
D013096:Spermine