title: Lysozyme in corneal ulcer.
abstract: In the present experimental study the role of lysozyme drops in healing of corneal ulcer of staphylococcal origin (sensitive to chloramphenicol) was studied on 16 albino rabbits. In 8 rabbits, in one eye placibo drops (distilled water) and in the other eye lysozyme 1% were put 4 times daily. In the other 8 rabbits, in one eye chloramphenicol drops 0.4% and in the other eye chloramphenicol drops 0.4% + lysozyme drops 1% were instilled 4 times daily. It was observed that the rate of healing of corneal ulcer was much earlier in the eyes which had local instillation of chloramphenicol drops + lysozyme in comparison to the eyes which had only chloramphenicol drops, lysozyme drops, or distilled water.
mesh_terms: D000818:Animals; D002701:Chloramphenicol / Q000627:therapeutic use; D003320:Corneal Ulcer / Q000188:drug therapy*; D009113:Muramidase / Q000008:administration & dosage / Q000627:therapeutic use*; D009883:Ophthalmic Solutions; D011817:Rabbits; D012075:Remission, Spontaneous
chemical_list: D009883:Ophthalmic Solutions; D002701:Chloramphenicol; D009113:Muramidase