title: [A comparative study of activity of nucleic acid metabolism in human embryonic liver].
abstract: In nuclei of hepatocytes of human embryos from the 18th to 40th week of antenatal development the activity of synthesis enzymes lowers: thymidine kinase is 7 times at low, uridine kinase - 11 times as low. In parallel during the same period a decrease in the activity of nucleases drops: DNase - by 15 times, RNase - by 11 times. The activity of these enzymes in the liver of adult persons (22-35 years old) is similar to their activity in the liver of human embryo to the moment of birth.
mesh_terms: D000328:Adult; D002467:Cell Nucleus / Q000201:enzymology*; D004247:DNA / Q000378:metabolism*; D003851:Deoxyribonucleases / Q000378:metabolism; D005260:Female; D005333:Fetus / Q000201:enzymology; D005865:Gestational Age; D006801:Humans; D008099:Liver / Q000196:embryology / Q000201:enzymology*; D011247:Pregnancy; D012313:RNA / Q000378:metabolism*; D012260:Ribonucleases / Q000378:metabolism; D013937:Thymidine Kinase / Q000378:metabolism; D014541:Uridine Kinase / Q000378:metabolism
chemical_list: D012313:RNA; D004247:DNA; D013937:Thymidine Kinase; D014541:Uridine Kinase; D003851:Deoxyribonucleases; D012260:Ribonucleases