[Oxygen metabolism in the body during substitution of nitrogen by helium in the air].
The total gas exchange, body temperature, content of free oxygen in the quadriceps muscle and its changes upon oxygen inhalation of a known dosage (oxygen test) were measured in the Wistar rats during their one-hour exposure to a helium-oxygen atmosphere (21%) at 25 degrees C. In this atmosphere the animals displayed a 1.8 degrees decline in the body temperature, a 20.5% increase in the gas exchange and a 26% decrease of oxygen in the muscular tissue as compared with the respective parameters in the air. After the experiment during the first 20 min exposure to the normal atmosphere oxygen tests were 10-15% lower than before the experiment. These findings give evidence for an increase of oxygen exchange in the muscles of animals exposed to the helium-oxygen atmosphere at a temperature below the comfortable level.
D000818:Animals; D001831:Body Temperature; D006371:Helium; D008297:Male; D009132:Muscles / Q000378:metabolism; D010100:Oxygen; D010101:Oxygen Consumption; D010313:Partial Pressure; D051381:Rats
D006371:Helium; D010100:Oxygen
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