title: [Directed biosynthesis of proteolytic enzymes in Actinomyces thermovulgaris].
abstract: The biosynthesis of proteolytic enzymes in the thermophilic culture of Actinomyces thermovulgaris, strain T-54, was directed by changing the composition of the medium and the temperature of cultivation. A temperature of 40 degrees C is optimal for the growth and production of neutral and alkaline proteases. The maximum activity of acid proteases was found during the growth on a complex medium at 30 degrees C. An increase of temperature to 50 degrees C during the cultivation of the microorganism on a chemically defined medium resulted in its secondary growth and a sharp rise in the activity of alkaline and neutral proteases.
mesh_terms: D000190:Actinomyces / Q000201:enzymology* / Q000254:growth & development; D003470:Culture Media; D010447:Peptide Hydrolases / Q000096:biosynthesis*; D013696:Temperature
chemical_list: D003470:Culture Media; D010447:Peptide Hydrolases
vernacular_title: Napravlennyĭ biosintez proteoliticheskikh fermentov u Actinomyces thermovulgaris