[The mechanism of action of thyrocalcitonin on myocardial cells].
Thyrocalcitonin preserved its effect on the electric and contractile activity of the myocardial cells even under the influence of 2,4-dinitrophenol. Administration of the hormone during a considerable drop in amplitude and duration of the action potential due to DNP effect led to increase in the amplitude and to a still greater decrease in duration of the action potential. The contraction amplitude reduced by DNP was also augmented by the hormone administration.
D000818:Animals; D001001:Anura; D002116:Calcitonin / Q000494:pharmacology*; D004140:Dinitrophenols / Q000494:pharmacology; D004347:Drug Interactions; D005071:Evoked Potentials / Q000187:drug effects; D006321:Heart / Q000187:drug effects*; D009200:Myocardial Contraction / Q000187:drug effects; D013268:Stimulation, Chemical
D004140:Dinitrophenols; D002116:Calcitonin
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