Renal glucose utilization in genetically diabetic microangiopathy.
Glucose uptake into kidney tissue is not influenced by the development of glomerulosclerosis in KK mice. Glucosyltransferase activity remains at a normal level even at an age having a highest incidence of serious development of glomerulosclerosis. The observation suggests that biosynthesis of basement membrane reflected by its glucosyltransferase activity does not accelerate in genetically transmitted microangiopathy.
D000818:Animals; D003094:Collagen / Q000378:metabolism; D003925:Diabetic Angiopathies / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism*; D005964:Glucosyltransferases / Q000378:metabolism; D007668:Kidney / Q000378:metabolism*; D051379:Mice; D014532:Uridine Diphosphate Glucose / Q000378:metabolism
D003094:Collagen; D005964:Glucosyltransferases; D005947:Glucose; D014532:Uridine Diphosphate Glucose