[Identification by means of heat denaturation of chromosome aberrations in 6 human metastatic tumors].
The method of chromosome reverse banding was applied to cancer cells. 95 mitotic figures, obtained from 6 histologically different metastatic effusions, in man were studied. This method gives a precise identification of numerical and structural abnormalities in chromosomes. Every possible type of chromosome mutation was observed. The chromosome accidents are different according to their frequence and their stability. This seems to be linked with the genetic contents.
D000230:Adenocarcinoma / Q000235:genetics; D001943:Breast Neoplasms / Q000235:genetics; D001984:Bronchial Neoplasms / Q000235:genetics; D002869:Chromosome Aberrations; D005260:Female; D006358:Hot Temperature; D006801:Humans; D007621:Karyotyping / Q000379:methods; D008297:Male; D008654:Mesothelioma / Q000235:genetics; D009362:Neoplasm Metastasis; D009691:Nucleic Acid Denaturation; D010996:Pleural Effusion / Q000473:pathology; D014178:Translocation, Genetic; D014314:Trisomy
Identification par dénaturation thermique ménagée des anomalies chromosomiques observées dans six tumeurs métastatiques humaines