title: Cardiac limitation to maximal oxygen transport and changes in components after jogging across the US.
abstract: Observations were made before and 3-5 days after prolonged endurance jogging an average of 42 miles/day, 6 days/wk for 2.5 mo by a young male adult who voluntarily initiated a run across the United States. Both arterial PO2 and lactic acid increased. In each instance, the first limitation in circulatory delivery of oxygen was a plateau in stroke volume and cardiac output. Afterward, pulse deficit and systemic arterial pressure fell with exercise and heart rate accelerated. Although there was no change in oxygen transport (Q X CAO2), a reduction in stroke volume was exactly balanced by a rise in arterial oxygen content. Vital capacity, residual volume, and total lung capacity and diffusion capacity for carbon monoxide, hematocrit, and red cell mass increased, while plasma volume diminished and heart size and total blood volume were unchanged.
mesh_terms: D000328:Adult; D001794:Blood Pressure; D002302:Cardiac Output; D006339:Heart Rate; D006801:Humans; D007590:Jogging; D008297:Male; D010100:Oxygen / Q000097:blood*; D012119:Respiration; D013177:Sports; D013997:Time Factors; D014481:United States
chemical_list: D010100:Oxygen