The "Barrett syndrome" (the columnar-lined lower oesophagus): an acquired condition secondary to reflux oesophagitis. A case report with discussion of pathogenesis.
A case of the "Barrett syndrome" in a patient with severe ulcerating reflux oesophagitis is reported. Evidence indicating that it is an acquired condition caused by reflux of bile-contaminated gastric juice is presented. The "Barrett ulcer" and the oesophagitis healed following a partial gastrectomy with a Roux-en Y gastrojejunostomy. The substitution of the squamous epithelium of the lower 15 cm of the oesophagus by columnar epithelium of cardia type is apparently irreversible.
D004940:Esophageal Stenosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D004942:Esophagitis, Peptic / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D004947:Esophagus / Q000000981:diagnostic imaging; D005764:Gastroesophageal Reflux / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography