[The role of disorders of "non-specific systems" of the brain in the pathogenesis of the Parkinsonian syndrome].
The authors conducted a clinico-physiological analysis of the syndrome of parkinsonism in different functional states (intense vigilance, flaccid vigilance, various phases and stages of night sleep, a hypnotic state) using the method of a polygraphic registration and an experimental-psychological study. The functional state of so-called nonspecific brain systems in parkinsonism and their disturbances in the pathogenesis of the disease was studied. A complicated character of shifts in different chains of the non-specific systems with various clinical forms and at different stages of the diseases were demonstrated. The authors proposed a method of quantitative evaluation of these shifts. It was demonstrated that motor, emotional-vegetative, somnic and electroencephalographic manifestations in parkinsonism correlated with the character and degree of the pathological changes in the non-specific, mainly activating brain systems.
D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis; D004569:Electroencephalography; D004576:Electromyography; D006801:Humans; D006990:Hypnosis; D007980:Levodopa / Q000627:therapeutic use; D008875:Middle Aged; D010302:Parkinson Disease, Secondary / Q000188:drug therapy / Q000209:etiology*; D011599:Psychopathology; D012154:Reticular Formation; D012894:Sleep Stages; D014851:Wakefulness
D007980:Levodopa
Rol' narushenii "nespetsificheskikh sistem" mozga v patogeneze sindroma parkinsonizma