Studies on the effect of allicin (diallyl disulphide-oxide) on alloxan diabetes.
On oral administration to alloxan diabetic rabbits, allicin produces an increase in its hypoglycemic action with relation to dose. A short-term treatment  with allicin, as well as with tolbutamide, significantly reduced the blood sugar levels and glucose nitrogen ratio of the above animals.
D000498:Allyl Compounds / Q000627:therapeutic use; D000818:Animals; D001786:Blood Glucose; D002364:Caseins; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy*; D004220:Disulfides; D006029:Glycosuria; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D009584:Nitrogen / Q000652:urine; D011817:Rabbits; D013441:Sulfinic Acids / Q000627:therapeutic use*; D014044:Tolbutamide / Q000627:therapeutic use*
D000498:Allyl Compounds; D001786:Blood Glucose; D002364:Caseins; D004220:Disulfides; D007004:Hypoglycemic Agents; D013441:Sulfinic Acids; C006452:allicin; D014044:Tolbutamide; D009584:Nitrogen