title: Hydroxyproline and hydroxylysine in different tissues of human embryos.
abstract: The collagen content in various tissues of human embryos was studied at four different steps of the maturation process. The umbilical cord of a 16-17 week old embryo was found to be active in collagen biosynthesis, Tibia, articular cartilage and skin showed of a peak of total hydroxyproline in the 16-17th week, decreasing later on, while the hydroxyproline decreased in umbilical cord from the 15-16th week to the 24th week. Hydroxylysine followed the hydroxyproline changes in articular cartilage and umbilical cord.
mesh_terms: D001842:Bone and Bones / Q000196:embryology / Q000378:metabolism; D002358:Cartilage, Articular / Q000196:embryology / Q000378:metabolism; D003094:Collagen / Q000096:biosynthesis*; D004622:Embryo, Mammalian / Q000378:metabolism*; D005865:Gestational Age; D006801:Humans; D006901:Hydroxylysine / Q000378:metabolism*; D006909:Hydroxyproline / Q000378:metabolism*; D012867:Skin / Q000196:embryology / Q000378:metabolism; D014470:Umbilical Cord / Q000378:metabolism
chemical_list: D006901:Hydroxylysine; D003094:Collagen; D006909:Hydroxyproline