[Physiology and biochemistry of streptomycetes. III. Incorporation of D-glucose-u-14C in paramomycin as indicator of antibiotic biosynthesis by Streptomyces albus var. metamycinus nov. var].
Paromomycin was isolated from culture filtrates of Streptomyces albus var. metamycinus nov. var. after feeding the growing cultures with D-glucose-u-14C. From the different incorporation rates conclusions concerning different features of the paromomycin biosynthesis (utilization of the carbon source, proportional and disproportional changes of the rates of synthesis) could be drawn. Uptake and metabolism of glucose are discussed.
D003470:Culture Media; D005285:Fermentation; D005947:Glucose / Q000378:metabolism*; D010303:Paromomycin / Q000096:biosynthesis*; D013302:Streptomyces / Q000254:growth & development / Q000378:metabolism*
D003470:Culture Media; D010303:Paromomycin; D005947:Glucose
Phsiologie und Biochemie der Streptomyceten. III. Einbau von D-Glucose-u-14C in Paromomucin als Indikator für die Antibioticabildung durch Streptomyces albus var. metamycinus nov. var.