Corticosteroid-like effect of cyproterone and cyproterone acetate in mice.
Cyproterone and cyproterone acetate exert the corticoid-like effect on the adrenal and spleen weight in the mice. When compared with prednisone, cyproterone acetate has approximately 1/5 of the corticoid potency of prednisone, expressed by the decrease of the spleen weight.
D000311:Adrenal Glands / Q000187:drug effects*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D003534:Cyproterone / Q000494:pharmacology*; D008297:Male; D051379:Mice; D009929:Organ Size / Q000187:drug effects; D011241:Prednisone / Q000494:pharmacology; D012669:Seminal Vesicles / Q000187:drug effects*; D013154:Spleen / Q000187:drug effects*; D013739:Testosterone / Q000037:antagonists & inhibitors
D013739:Testosterone; D003534:Cyproterone; D011241:Prednisone