title: Five years experience with the Björk-Shiley tilting disc valve in isolated aortic valvular disease.
abstract: The non-overlapping tilting disc of the Björk-Shiley prosthesis has proved its efficiency in two respects: It provides an optimal orifice to tissue diameter ratio with a favourable rheology both at rest and during exercise even in the smaller valve sizes used for insertion in narrow aortic roots. It accounts for a minimal haemolysis because mechanical crushing of the red cells is minimized by such a non-overlapping closing mechanism. Regurgitation is negligible. The excellent durability of the prosthesis has been clinically testified. Thrombo-embolism has not so far occurred with effective Dicumarol treatment. Aortic valve replacement with the Björk-Shiley tilting disc valve is regarded as an elimination of the volume load of the left ventricle in AI and the pressure load in AS, thereby creating a pre-requisite for a normalization of the pump function of the heart.
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D001021:Aortic Valve / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000209:etiology; D005069:Evaluation Studies as Topic; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects / Q000401:mortality / Q000592:standards; D006439:Hemodynamics; D006461:Hemolysis; D006801:Humans; D008875:Middle Aged; D013923:Thromboembolism / Q000209:etiology / Q000517:prevention & control
chemical_list: D000925:Anticoagulants