Is the basal activity of rat stomach histidine decarboxylase affected by antrectomy?
The serum gastrin concentration and the gastric histidine decarboxylase activity are high in freely fed, unoperated rats but low in antrectomized rats. Following food deprivation the serum gastrin level and the enzyme activity are reduced simultaneously in the unoperated rats. After fasting for 36-48 h - but not before - the enzyme activity drops to the same low levels as in antrectomized rats.
D000818:Animals; D002262:Carboxy-Lyases / Q000378:metabolism*; D005215:Fasting; D005753:Gastric Mucosa / Q000201:enzymology*; D005755:Gastrins / Q000097:blood*; D006640:Histidine Decarboxylase / Q000378:metabolism*; D008297:Male; D011706:Pyloric Antrum / Q000502:physiology*; D051381:Rats; D013997:Time Factors
D005755:Gastrins; D002262:Carboxy-Lyases; D006640:Histidine Decarboxylase