Regional blood flow in rats exposed to supralethal doses of whole body x-irradiation.
Relative blood flow in different organs of the supralethally (3 kR) whole body X-irradiated rat was studied using labeled 15 mu microspheres. Immediately after irradiation blood flow in brain diminishes. From 10 to 20 hrs a phase of increase in blood flowing to many parenchymal organs ensues. A second maximum 45 to 50 hrs and a third one at 60 hrs. In most organs except in brain and liver relative blood flow diminishes before death. The genesis of these changes as signs of a slowly developing shock is discussed.
D000818:Animals; D001921:Brain / Q000098:blood supply; D007421:Intestine, Small / Q000098:blood supply; D007668:Kidney / Q000098:blood supply; D008099:Liver / Q000098:blood supply; D008168:Lung / Q000098:blood supply; D008297:Male; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D051381:Rats; D012039:Regional Blood Flow / Q000528:radiation effects*; D013154:Spleen / Q000098:blood supply; D013270:Stomach / Q000098:blood supply; D013737:Testis / Q000098:blood supply; D014965:X-Rays