[Use of leukocytes labelled with 99m Technetium sulfide colloids for the detection of experimental aseptic inflammatory foci].
The authors propose a technique of labelling of leukocytes based on the phagocytic power of these cells with regard to sulphide particles in the colloidal state labelled with 90mmTc. These labelled leukocytes maintain their normal function and can be detected in the inflammatory foci created in experimental animals in the form of an abscess. Satisfactory results were thus obtained by scintiscanning after auto and allo-transfusion of labelled leukocytes. The role of hyperemia in the results obtained is eliminated by comparative study using non-diffusible vascular tracers. The type of vector, tracer and marker, the innocuity of the method suggest that it may be used in human clinical medicine for the early diagnosis of certain inflammatory foci.
D000038:Abscess / Q000175:diagnosis*; D000818:Animals; D003102:Colloids; D004285:Dogs; D007204:Indium; D007553:Isotope Labeling; D007962:Leukocytes; D010587:Phagocytosis; D011877:Radionuclide Imaging; D013440:Sulfides; D013667:Technetium
D003102:Colloids; D013440:Sulfides; D007204:Indium; D013667:Technetium
Utilisation de leucocytes marqués par des colloïdes de sulfure de Technétium 99m pour la détection des foyers inflammatoires aseptiques expérimentaux