[Changes in hemodynamics in patients with chronic alcholism].
The indices of total hamodynamics were studied in 52 patients with chronic alcoholism and without any clear signs of cardiac pathology and with normal arterial pressure. When examined at rest in a supine position they exhibited normal values of the cardiac and stroke index, peripheral vascular resistance, circulating blood volume and hematocrit. Along with the increasing period of alcohol abuse the cardiac index gets somewhat decreased, indicating a decreasing contractile capacity of the myocardium. This is further supported by the changing structure of the phases of the systole: prolongation of the phase of isometric contraction, of the tension phase, the tension index, reduction of the intrasystolic index and of the speed of intraventricular pressure increase. The orthostatic test revealed certain disorders in the regulation of the cardiovascular system in an upright position which manifested themselves in a more distinct, than in normal individuals, reduction of the cardiac and stroke indices, and in a more significant growth of cardiac contractions rate and peripheral vascular resistance. The latter indicates an increased mobilization of the sympathoadrenal system in an orthostatic position.
D000328:Adult; D000437:Alcoholism / Q000503:physiopathology*; D001794:Blood Pressure; D001810:Blood Volume; D002302:Cardiac Output; D002908:Chronic Disease; D005260:Female; D006321:Heart / Q000503:physiopathology; D006400:Hematocrit; D006439:Hemodynamics; D006801:Humans; D008297:Male; D009200:Myocardial Contraction; D014655:Vascular Resistance
Izmeneniia gemodinamiki u bol'nykh khronicheskim alkogolizmom