[Effect of immunization of mice with live viral vaccines on bone marrow cell chromosomes in 1st generation progeny].
In bone marrow cells of the first generation progeny obtained from mice intensively immunized with live antiviral vaccines (poliovaccine, measles and smallpox vaccines) an increase of chromosome frequency aberrations is observed mainly due to chromatid breaks. Simultaneously a considerable delay in growth was determined for progeny obtained from the vaccinated animals as compared with the control.
D000818:Animals; D002869:Chromosome Aberrations; D005260:Female; D008297:Male; D008458:Measles Vaccine / Q000009:adverse effects; D051379:Mice; D011054:Poliovirus Vaccine, Inactivated / Q000009:adverse effects; D012900:Smallpox Vaccine / Q000009:adverse effects; D014611:Vaccination / Q000009:adverse effects*; D014613:Vaccines, Attenuated / Q000009:adverse effects*; D014765:Viral Vaccines / Q000009:adverse effects*
D008458:Measles Vaccine; D011054:Poliovirus Vaccine, Inactivated; D012900:Smallpox Vaccine; D014613:Vaccines, Attenuated; D014765:Viral Vaccines
Vliianie immunizatsii mysheĭ zhivymi protivovirusnymi vaktsinami na khromosomy kletok kostnogo mozga potomstva pervogo pokoleniia