Initiation of human parturition. II. Identification of phospholipase A2 in fetal chorioamnion and uterine decidua.
In this study, the presence of a phospholipase has been demonstrated in the human chorioamnion and uterine decidua. That the chorioamnionic enzyme is of the phospholipase A2 type was established by product identification following the incubation of the enzyme with either radioactive phosphatidylcholine or phosphatidylethanolamine. The potential relationship between the expression of the activity of this enzyme and the regulation of arachidonic acid release, prostaglandin formation, and the initiation of labor is considered.
D000650:Amnion / Q000032:analysis / Q000201:enzymology*; D001095:Arachidonic Acids / Q000378:metabolism; D002823:Chorion / Q000032:analysis / Q000201:enzymology*; D003656:Decidua / Q000032:analysis / Q000201:enzymology*; D005321:Extraembryonic Membranes / Q000201:enzymology*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007743:Labor, Obstetric; D010740:Phospholipases / Q000378:metabolism*; D011247:Pregnancy; D011453:Prostaglandins / Q000096:biosynthesis*
D001095:Arachidonic Acids; D011453:Prostaglandins; D010740:Phospholipases