title: [Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
abstract: We have studied a series of sixteen free amino-acids as well as total blood amino-acid and liquor amino-acids in 56 women between the 25th and 44th weeks of pregnancy. The results have been analysed statistically and demonstrated graphically. The amino-acid levels rise from the 25th week of the pregnancy until term (p less than 0.05) in peripheral blood. On the other hand the total level of amino-acids in the amniotic fluid drops from the 25th week of pregnancy remarkably (p less than 0,01). Different amino-acids show different curves. The increase in the level of total blood amino-acids is principally due to a rise in glycine and leucine, while the other amino-acids as a whole stay constant. The spectrum of amino-acids in the amniotic fluid is however a little different and the drop in total amino-acids if principally due to the threonine-serine fraction and partly to the glutamine, proline, alanine, lysine and valine elements, whereas the rest stay the same or even raised.
mesh_terms: D000409:Alanine / Q000032:analysis; D000596:Amino Acids / Q000032:analysis* / Q000097:blood; D000653:Amniotic Fluid / Q000032:analysis*; D003545:Cysteine / Q000032:analysis; D005260:Female; D005998:Glycine / Q000032:analysis; D006639:Histidine / Q000032:analysis; D006801:Humans; D007532:Isoleucine / Q000032:analysis; D007930:Leucine / Q000032:analysis; D008239:Lysine / Q000032:analysis; D008715:Methionine / Q000032:analysis; D009952:Ornithine / Q000032:analysis; D010649:Phenylalanine / Q000032:analysis; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011392:Proline / Q000032:analysis; D012694:Serine / Q000032:analysis; D013912:Threonine / Q000032:analysis; D014443:Tyrosine / Q000032:analysis; D014633:Valine / Q000032:analysis
chemical_list: D000596:Amino Acids; D007532:Isoleucine; D013912:Threonine; D014443:Tyrosine; D012694:Serine; D010649:Phenylalanine; D006639:Histidine; D011392:Proline; D008715:Methionine; D009952:Ornithine; D007930:Leucine; D014633:Valine; D008239:Lysine; D003545:Cysteine; D000409:Alanine; D005998:Glycine
vernacular_title: Les acides aminés libres du liquide amniotique et du sang maternel au cours de la grossesse avancée