Idiopathic orthostatic hypotension controlled with a monoamine oxidase inhibitor and 9-alpha-fluorohydrocortisone.
A case of orthostatic hypotension with autonomic failure is presented, and the patient's clinical response to the combined regime of a monoamine oxidase inhibitor and 9-alpha-fluorohydrocortisone is discussed. This therapy provided a relatively convenient means of alleviating the patient's symptoms and appears to be of considerable value in the management of orthostatic hypotension. However, close patient supervision is essential when these drugs are used as they cause hypertension in the supine position in subjects with poor baroreceptor function.
D001794:Blood Pressure; D005438:Fludrocortisone / Q000627:therapeutic use*; D006225:Hand / Q000098:blood supply; D006801:Humans; D007024:Hypotension, Orthostatic / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000098:blood supply; D009638:Norepinephrine / Q000494:pharmacology; D010656:Phenylephrine / Q000627:therapeutic use*; D011187:Posture; D012039:Regional Blood Flow / Q000187:drug effects; D014636:Valsalva Maneuver
D010656:Phenylephrine; D005438:Fludrocortisone; D009638:Norepinephrine