title: Aspirin hepatitis.
abstract: Adverse reactions to aspirin, a potentially hepatotoxic drug, are believed to be dose related. This article reviews the medical literature and described two children with aspirin hepatitis. Hepatic dysfunction recurred in one of these patients at salicylate concentrations in serum previously considered nontoxic.
mesh_terms: D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications; D001171:Arthritis, Juvenile / Q000150:complications / Q000188:drug therapy*; D001219:Aspartate Aminotransferases / Q000097:blood; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D002648:Child; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy*; D008297:Male; D013997:Time Factors
chemical_list: D001219:Aspartate Aminotransferases; D001241:Aspirin