[Differential reaction of condensed and diffuse chromatin to polyamines. II. Effect of putrescine on the chromatin of mitotic chromosomes].
The response of euchromatin and heterochromatin to putrescine was studied using chinese hamster mitotic chromosomes with heterochromatic segments delayed in condensation due to BUdR treatment. These heterochromatic segments did not react to the condensing effect of putrescine looking during metaphase still more elongated. Additional decondensed segments occurred in chromosomes. This is interpreted as the condensing effect of putrescine on euchromatic segments which accelerates transition of the cells into metaphase with preserved BUdR-induced chromosomal decondensation.
D000818:Animals; D002843:Chromatin / Q000187:drug effects*; D006224:Cricetinae; D006570:Heterochromatin / Q000187:drug effects; D008938:Mitosis / Q000187:drug effects; D011700:Putrescine / Q000494:pharmacology*
D002843:Chromatin; D006570:Heterochromatin; D011700:Putrescine
Differentsial'naia reaktsiia kondensirovannogo i diffuznogo khromatina na poliaminy. II. Deĭstvie putrestsina na khromatin mitoticheskikh khromosom