[Prevention of thrombosis using acetylsalicylic acid following vascular prosthesis and endarterectomy].
In 20 dogs one common iliac artery was intimectomized, an equal segment of the other was replaced by a knitted dacron prosthesis. Ten animals were given Acetylsalicylic Acid 30 mg/kg BW/d. Four weeks later these arterial segments were examined grossly and histologically for the presence of thrombotic depositis. In the treated animals these segments always remained patent. Three of the untreated animals showed a complete thrombotic occlusion of the prosthesis. The amount of thrombotic deposits on intimectomized and prosthetics segments was clearly reduced in the treated animals.
D000818:Animals; D001241:Aspirin / Q000627:therapeutic use*; D001807:Blood Vessel Prosthesis; D004285:Dogs; D004691:Endarterectomy; D010973:Platelet Adhesiveness; D011183:Postoperative Complications / Q000517:prevention & control*; D013927:Thrombosis / Q000517:prevention & control*
D001241:Aspirin
Thromboseprophylaxe mit Acetylsalicylsäure nach prothetischem Gefässersatz und Endarteriektomie