Changes of electro-shock seizure threshold in alloxan diabetic rats.
During a 4-week period, the electroshock seizure threshold (EST) of R Amsterdam rats was determined. When alloxan induced diabetes, the EST values significantly decreased, while in the alloxan-treated non-diabetic group they remained unchanged. The results suggest that diabetes induces increased excitability in the central nervous system.
D000818:Animals; D001786:Blood Glucose; D002490:Central Nervous System / Q000503:physiopathology*; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology*; D004597:Electroshock; D005260:Female; D051381:Rats
D001786:Blood Glucose