[Formation of secretory antibodies in experimental influenza infection].
The principal peculiarities attending formation of specific secretory immunity in experimental influenza infection were marked individual variability and a relative autonomicity of accumulation of the secretory antibodies. Functional condition of the secretory immunity before the infection influenced the formation of antibodies in the secretions and the blood sera: when the concentration of the secretory antibodies before the infection constituted 1 : 8--1 : 16, general and secretory antibodies accumulated less intensively. There was a progressive fall of the concentration of the secretory immunoglobulin A in the majority of the volunteers the first 3 weeks after the infection. It is supposed that this process played a significant role in the pathogenesis of influenza complications.
D000917:Antibody Formation; D006801:Humans; D007070:Immunoglobulin A / Q000096:biosynthesis*; D007251:Influenza, Human / Q000276:immunology*; D009297:Nasal Mucosa / Q000276:immunology*
D007070:Immunoglobulin A
O formirovanii sekretornykh antitel pri éksperimental'noĭ grippoznoĭ infektsii