The activity of Newcastle disease virus-envelope proteins after treatment with detergents.
Treatment of NDV with anionic detergents or lipid solvents destroys the activities of hemagglutinin and neuraminidase. After disruption of the virus with non-ionic detergents, the activities of envelope proteins remain unchanged. It is suggested that the phosholipids are very important for the biological activity of NDV-envelope proteins.
D000818:Animals; D002642:Chick Embryo; D002645:Chickens; D003902:Detergents / Q000494:pharmacology*; D004986:Ether / Q000494:pharmacology; D006168:Guinea Pigs; D006387:Hemagglutination, Viral / Q000187:drug effects; D006461:Hemolysis / Q000187:drug effects; D009439:Neuraminidase / Q000378:metabolism; D009522:Newcastle disease virus / Q000187:drug effects* / Q000201:enzymology; D010743:Phospholipids / Q000378:metabolism; D014764:Viral Proteins / Q000378:metabolism*
D003902:Detergents; D010743:Phospholipids; D014764:Viral Proteins; D004986:Ether; D009439:Neuraminidase