Furosemide action on the creatinine concentration of amniotic fluid.
Creatinine concentration in the amniotic fluid (A.F.) of pre-eclamptic patients without treatment with furosemide was compared to the values obtained in normal pregnant women at the same stage of gestation. These values increased significantly when a diuretic treatment was started; no correlation was found with either maternal serum level or the A.F. volume. Furosemide treatment had no significant effect on A.F. volume in the pre-eclamptic group.
D000653:Amniotic Fluid / Q000032:analysis / Q000187:drug effects*; D003404:Creatinine / Q000032:analysis* / Q000097:blood; D005260:Female; D005665:Furosemide / Q000494:pharmacology* / Q000627:therapeutic use; D005865:Gestational Age; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood / Q000188:drug therapy; D011247:Pregnancy
D005665:Furosemide; D003404:Creatinine