title: Ligand-leakage in affinity chromatography: a second note on the mathematical approach.
abstract: A leakage function describing the hydrolytic release of ligand molecules covalently attached to insoluble supports by the CNBr method has been derived. Statistical factors were taken into account. The results of this random order model are compared with those of a consecutive order model proposed by Gribnau and Tesser.
mesh_terms: D002846:Chromatography, Affinity; D008024:Ligands; D008433:Mathematics; D008962:Models, Theoretical
chemical_list: D008024:Ligands