title: [Fibrinogen metabolism and distribution in tourniquet-trauma].
abstract: The distribution and turn-over of 131J-labelled fibrinogen was studied in traumatized rats. Tourniquet-trauma resulted in a pronounced accumulation of labelled fibrinogen in the traumatized region. The accumulation was at the expense of all nontraumatized-tissue. In controls there was a parallel decline of total-body-activity and plasmaactivity. The T.B.A. of traumatized animals showed a similar disapprearance-rate, while there was a pronounced reduction of circulating labelled fibrinogen.
mesh_terms: D000818:Animals; D005340:Fibrinogen / Q000378:metabolism*; D007457:Iodine Radioisotopes; D051381:Rats; D014111:Tourniquets / Q000009:adverse effects*; D014947:Wounds and Injuries / Q000378:metabolism*
chemical_list: D007457:Iodine Radioisotopes; D005340:Fibrinogen
vernacular_title: Fibrinogenstoffwechsel und Verteilung im Tourniquet-Trauma