Initiation of 3T3 fibroblast cell division by epidermal growth factor.
Epidermal Growth Factor (EGF) at concentrations of 10(-9) to 10(-10) M initiates cell division in both confluent and low density non-dividing 3T3 cells. Four days after addition of EGF to confluent or low density non-dividing 3T3 cells there is a 2- and 5-fold increase, respectively, in cell number.
D001769:Blood; D002452:Cell Count; D002455:Cell Division / Q000187:drug effects*; D002460:Cell Line; D002470:Cell Survival; D003470:Culture Media; D004305:Dose-Response Relationship, Drug; D006133:Growth Substances / Q000302:isolation & purification / Q000494:pharmacology*; D013936:Thymidine / Q000378:metabolism
D003470:Culture Media; D006133:Growth Substances; D013936:Thymidine