Long-term deficits after somatosensory cortical lesions in rats.
Rats having either sham operations or one-stage bilateral lesions of the two somatosensory areas of the cortex were tested for acquisition of five tactile discriminations after postoperative recovery intervals of 14, 35, 180, 365 or 730 days. The group with lesions performed worse than its time-matched control group in every instance, and there was no evidence for recovery of function with the longer postoperative recovery periods. These results suggest that time per se is not a significant determinant of restitution after somatosensory cortical ablations.
D000818:Animals; D001766:Blindness / Q000150:complications; D003289:Convalescence; D003337:Corpus Callosum / Q000502:physiology; D004193:Discrimination Learning / Q000502:physiology*; D007839:Functional Laterality; D008297:Male; D013508:Ophthalmologic Surgical Procedures; D051381:Rats; D013003:Somatosensory Cortex / Q000502:physiology*; D013997:Time Factors; D014110:Touch / Q000502:physiology*