title: Left ventricular pressure responses in post-angiographic angina.
abstract: Alterations in left ventricular end-diastolic pressure and in dp/dt observed in ten patients with coronary heart disease who developed angina pectoris following left ventricular cineangiography were compared with those of six other patients who developed angina spontaneously and with patients who underwent left ventricular cineangiography without experiencing angina. In the patients with post-angiographic angina there was a greater increase in end-diastolic pressure than that seen in the other patients, but there was no significant change in dp/dt. Changes in left ventricular pressure associated with post-angiographic angina would appear to reflect the combined effects of increased preload provided by the contrast material and of ventricular dysfunction including diminished compliance associated with angina. A rise in end-diastolic pressure greater than 20 mmHg following left ventricular cineangiography should alert the physician that the patient may be having myocardial ischemia.
mesh_terms: D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000209:etiology*; D001794:Blood Pressure; D006328:Cardiac Catheterization / Q000009:adverse effects; D002932:Cineangiography; D003287:Contrast Media / Q000009:adverse effects; D017023:Coronary Angiography; D003326:Coronary Circulation; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D004562:Electrocardiography; D006439:Hemodynamics; D006801:Humans
chemical_list: D003287:Contrast Media