title: Immunoglobulin Allotypes of European Populations. I. Gm and Km(Inv) allotypic markers in Hungarians.
abstract: The distribution of G1m(f, z, a, and x), G3m(b0, b1, b3, c3, c5, g, s, and t) and Km(1) (formerly Inv[1]) allotypic markers have been examined in 184 Hungarians. The results indicate that the frequency of the immunoglobulin haplotypes Gmza;g, Gmzax;g, Gmf;b and Km1 is similar to the frequencies observed in surrounding populations. In addition, Hungarians were found to be polymorphic for the Oriental haplotype Gmza;bst, and had low frequencies of other uncommon haplotypes. Our data indicate that about 5% of the Hungarian genome is of Oriental origin.
mesh_terms: D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D006238:Haploidy; D006801:Humans; D006814:Hungary; D007126:Immunoglobulin Allotypes; D010641:Phenotype; D011110:Polymorphism, Genetic
chemical_list: D007126:Immunoglobulin Allotypes