[The carcinogenic activity of small concentrations of nitrosodimethylamine when inhaled].
In experiments on Balb/c mice and Wistar rats the authors have studied the carcinogenic activity of nitrosodimethylamine (NDMA) in daily inhalations of the drug in concentrations of 0.005 mg/m3 and 0.2 mg/m3 during 17 months for mice and 25 months for rats. In the concentration of 0.2 mg/m3 tumors would arise considerably earlier and in larger amounts than in control animals, as well as in animals inhaling NDMA in the concentration of 0.005 mg/m3 and not differing in this respect from control animals.
D000818:Animals; D004128:Dimethylnitrosamine; D005260:Female; D007680:Kidney Neoplasms / Q000139:chemically induced; D008113:Liver Neoplasms / Q000139:chemically induced; D008175:Lung Neoplasms / Q000139:chemically induced; D008297:Male; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced; D051379:Mice; D009374:Neoplasms, Experimental / Q000139:chemically induced*; D009602:Nitrosamines; D051381:Rats
D009602:Nitrosamines; D004128:Dimethylnitrosamine
Kantserogennoĭ aktivnosti malykh kontsentratsiĭ nitrozodimetilamina pri ingaliatsii