Oncocytic change in mucoepidermoid carcinoma of the parotid gland.
Among the morphological features of an oncocytic mucoepidermoid carcinoma of the parotid salivary gland in a 78-year-old man, the oncocytes had granular eosinophilic cytoplasm that was characterized ultrastructurally by large numbers of mitochondria that displayed minimal abnormalities. Complex cell-to-cell relationship, well-developed junctival complexes, and microvillous-like surface projections suggestive of ductal differentiation were present; epidermoid features in the form of dense focal aggregates of cytoplasmic fibrils were also seen.
D000236:Adenoma / Q000150:complications / Q000473:pathology*; D000368:Aged; D002277:Carcinoma / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D010306:Parotid Gland / Q000473:pathology* / Q000648:ultrastructure; D010307:Parotid Neoplasms / Q000473:pathology*