Haematoporphyrins in the diagnosis and treatment of carcinoma of the bladder.
The localization of an haematoporphyrin derivative (HpD) was studied in the operative specimens of three patients with carcinoma of the bladder. The drug was found to localize preferentially in malignant and premalignant mucosa and not in normal bladder tissues. It is suggested that HpD fluorescence might be useful as a diagnostic aid and its photosensitizing properties be used as a mode of therapy for carcinoma of the bladder.
D000230:Adenocarcinoma / Q000378:metabolism; D002278:Carcinoma in Situ / Q000378:metabolism; D006415:Hematoporphyrins / Q000378:metabolism; D006801:Humans; D001743:Urinary Bladder / Q000378:metabolism; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy
D006415:Hematoporphyrins