[An electron-autoradiographic study of capillaries in malignant tumors].
Using electron microscopy the ultra structure of endothelial cells in malignant tumors (myogenic sarcomas), removed in 6 patients, was investigated. It was found that endothelial cells of blood capillaries in malignant neoplasms show some peculiar features in the basal layer structure and in formation of a multitude of orifices of various diameter in the capillary wall. Electron radiographic investigations of endothelial cells of a transplantable sarcoma strain in the experiment have evidenced a greater number of ribosomes in the cytoplasm and enhancement of the DNA synthesis in nuclei. These findings are indicative of increased proliferative properties of these cells.
D000818:Animals; D001345:Autoradiography; D002196:Capillaries / Q000648:ultrastructure*; D004273:DNA, Neoplasm / Q000096:biosynthesis; D004727:Endothelium; D006801:Humans; D051379:Mice; D008808:Mice, Inbred CBA; D008854:Microscopy, Electron; D009217:Myosarcoma / Q000378:metabolism / Q000473:pathology*; D012513:Sarcoma, Experimental / Q000473:pathology
D004273:DNA, Neoplasm
Elektronnoavtoradiograficheskoe issledovanie kapilliarov v zlokachestvennykh opukholiakh