Ultrastructural changes in the neural lobe of the rat pituitary induced by reserpine treatment.
The doses of reserpine, which are generally used to deplete amines from the nervous tissue caused marked ultrastructural changes in the neural lobes of reserpine treated rats. The findings suggested depletion of neurosecretory granules, increased lysosomal activity and changes in the pituicytes.
D000818:Animals; D010904:Pituitary Gland, Posterior / Q000187:drug effects / Q000648:ultrastructure*; D051381:Rats; D012110:Reserpine / Q000494:pharmacology*
D012110:Reserpine