Anti-Holley (hy): characterization of another example.
Anti-Hy, in a serum of a black man who had received multiple blood transfusions, was found to be a warm reactive and polyclonal IgG antibody which did not bind complement in vitro. 51Cr-labeled Hy-positive red blood cells in the patient showed a shortened "2-component" survival curve. Hy antigens were not detected on leukocytes, platelets, or in the serum of Hy-positive individuals.
D000327:Adsorption; D000328:Adult; D001789:Blood Group Antigens; D003168:Complement Fixation Tests; D003298:Coombs Test; D003601:Cytotoxicity Tests, Immunologic; D004905:Erythrocyte Aging; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007518:Isoantibodies / Q000032:analysis; D008297:Male
D001789:Blood Group Antigens; D007074:Immunoglobulin G; D007518:Isoantibodies