[Interaction of homoeotic mutations Antennapedia and Polycomb in Drosophila melanogaster].
Pairwise interaction of three alleles of Antennapedia (Antp49, Antp 50 and APX) with two alleles of Polycomb (Pc1 and Pc2) considerably increased homoeotic transformation of antennae caused by Antennapedia gene (up to the formation of completely developed homoeotic legs). On the contrary, Antennapedia alleles decreased the transformation of meso- and metatoracic legs into protoracic legs, as caused by Pc alleles. The degree of changes in the expression of Antp and Pc due to intergenic interaction were, as a rule, Antennapedia specific, i.e. the differences were greater when Antp alleles were substituted in genotypes. A possible mechanism of the interaction observed is discussed.
D000818:Animals; D002454:Cell Differentiation
Vzaimodeĭstvie gomeozisnykh mutatsiĭ Antennapedia i Polycomb u Drosophila melanogaster