title: [Oxidative conversion of vitamin "A" in rats with different allowances of it].
abstract: The effects of vitamin "A" insufficiency and of its toxic doses on the activity of alcoholdehydrogenase oxidizing retinol and ethanol and on that of aldehydoxidase, oxidizing retinal in the liver, kidneys and small intestine of rats were studied. It is shown that in case of "A"-vitamin insufficiency are on the rise processes of oxidative transformation of retinol and retinal associated with an increased activity of alcoholdehydrogenase and aldehoxidase. Against the background of toxic doses of vitamin "A" THe activity of alcoholdehydrogenase in the organs under investigation is inhibited and that of aldhydoidase in the small intestine rises.
mesh_terms: D000429:Alcohol Oxidoreductases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000445:Aldehyde Oxidoreductases / Q000378:metabolism*; D000818:Animals; D007421:Intestine, Small / Q000201:enzymology; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D010084:Oxidation-Reduction; D051381:Rats; D012172:Retinaldehyde / Q000378:metabolism; D014801:Vitamin A / Q000009:adverse effects* / Q000378:metabolism; D014802:Vitamin A Deficiency / Q000378:metabolism*
chemical_list: D014801:Vitamin A; D000429:Alcohol Oxidoreductases; D000445:Aldehyde Oxidoreductases; D012172:Retinaldehyde
vernacular_title: Okilsitel'nye prevrashcheniia vitamina A y krys v usloviiakh razlichnogo obespecheniia etim vitaminom