title: [Thiourea derivatives of 1,3,4-thiadiazole and their cyclization products].
abstract: The synthesis and chemical behaviour of 1-methoxycarbonyl-3-(1,3,4-thiadiazol-2-yl)thyoureas and 7-alkyl-2-methyltio-1,3,4-thiadiazolo [3,2-a]-s-triazine-4-ones is described. All compounds were tested in vitro for their antibacterial activity.
mesh_terms: D001419:Bacteria / Q000187:drug effects; D003500:Cyclization; D004353:Drug Evaluation, Preclinical; D008826:Microbial Sensitivity Tests; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D013890:Thiourea / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology
chemical_list: D013830:Thiadiazoles; D013890:Thiourea
vernacular_title: Derivati tioureici dell'1,3,4-tiadiazolo e loro prodotti di ciclizzazione