[Cardiovascular reflex-reactions on the blood volume changes before and after pharmacological elimination of the efferent heart innervation].
Reflex changes in the heart frequency, blood pressure and respiratory frequency induced by slow changes of the blood volume are observed in the aesthetized European hamster (Cricetus cricetus L.). Tachycardia, hypertension and hyperpnoe occured during intravenous infusion and bradycardia, hypotension and respiratory inhibition during hemorrhages or local distensions of the junction between the superior vena cava and the right atrium. Various receptor organs of the heart and the great vessels and sympathetic as well as parasympathetic effector mechanisms were involved in the reflex effects. An activation of efferent vagal fibers decreased blood pressure and heart frequency; an excitation of efferent sympathetic fibers increased blood pressure and heart frequency.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001810:Blood Volume / Q000187:drug effects*; D006224:Cricetinae; D005283:Fentanyl / Q000494:pharmacology; D006321:Heart / Q000294:innervation* / Q000502:physiology; D006339:Heart Rate / Q000187:drug effects*; D006493:Heparin / Q000494:pharmacology; D007601:Jugular Veins; D012018:Reflex / Q000187:drug effects*; D012024:Reflex, Oculocardiac / Q000187:drug effects*
D001285:Atropine; D006493:Heparin; D005283:Fentanyl
Kardiovaskuläre Reflexantworten auf Blutvolumenänderungen vor und nach einer pharmakologischen Ausschaltung der efferenten Herzinnervation