[Distribution of the isoenzym lactatdehydrogenase in human cartilage (author's transl)].
The analysis of the lactatdehydrogenase (LDH)-isoenzym patterns in normal human cartilage will be of valuable help in the interpretation of enzymological data in cases of pathological joint changes. It may allow conclusions about the situation of the metabolism in a joint according to the particular circumstances. As so far no representative investigations into normal human cartilage have become known, the attempt has been made in this paper to evaluate the LDH-isoenzym pattern in normal cartilage. The result indicates that in normal human joint cartilage the LDH-5 dominates with an average of 75.3%, whereas the LDH-4 (21.7%) and the LDH-3 (3.2%) are considerably lower. Thus the result fits well into the joint cartilage data which have been published so far.
D000293:Adolescent; D002358:Cartilage, Articular / Q000201:enzymology* / Q000378:metabolism; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
Zur Lactatdehydrogenase-Isoenzymverteilung im menschlichen Knorpel