In vitro susceptibility of selected bacteria to three diphosphonia heterocyclic compounds.
The antibacterial activity of 1,1,4,4-tetraphenyl-1,4-diphosphonia-2,5-diphenylcyclohexadi-2,5-ene dichloride and two of its derivatives were screened for activity using the disk method. All derivatives exhibited antibacterial activity against gram-positive organisms tested, but little inhibition of gram-negative species was noted.
D001419:Bacteria / Q000187:drug effects*; D003510:Cyclohexanes / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009861:Onium Compounds / Q000494:pharmacology*; D009943:Organophosphorus Compounds / Q000494:pharmacology*
D003510:Cyclohexanes; D009861:Onium Compounds; D009943:Organophosphorus Compounds