title: Basic principles of nuclear organization.
abstract: The preceding discussion is summarized in Table 1. It is clear that the organization of the genetic material and the ability to transmit information to the cytoplasm involve a number of different components that must maintain specific chemical and physical relationships to one another. An alteration of any of these relationships could affect a variety of cellular processes, including development.
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000032:analysis* / Q000648:ultrastructure; D002843:Chromatin / Q000032:analysis; D002875:Chromosomes / Q000032:analysis; D004247:DNA / Q000032:analysis; D004261:DNA Replication; D005809:Genes, Regulator; D006570:Heterochromatin / Q000032:analysis; D006657:Histones / Q000032:analysis; D006801:Humans; D008566:Membranes; D008938:Mitosis; D008956:Models, Chemical; D009698:Nucleoproteins / Q000032:analysis*; D010455:Peptides / Q000032:analysis
chemical_list: D002843:Chromatin; D006570:Heterochromatin; D006657:Histones; D009698:Nucleoproteins; D010455:Peptides; D004247:DNA