[Dopamine receptors of the diencephalon associated with the endocrine function of the hypophyseal-testicular system].
One hour after local administration of 1 gamma of dopamine into the medial portion of the subthalamus or into the central grey matter of the caudal portion of the thalamus of male Wister rats testosterone level (determined fluorimetrically) more than doubled in the peripheral blood plasma. A similar effect was produced by apomorphine (2 gamma), stimulant of dopamine receptors, administered into the same areas of the diencepalon. No increase in testosterone content followed local administration of dopamine into the arcuate nuclei of the hypothalamus. A conclusion was drawn that dopamine receptors of the diencephalon associated with the endocrine function of the male gonad were located in the medial portion of the subthalamus and in the area of the central grey matter of the posterior portion of the thalamus. At the same time, dopamine neurons of the arcuate nuclei of the hypothalamus apparently took no part in the regulation of the endocrine function of the hypophysio-testicular system.
D000818:Animals; D001058:Apomorphine / Q000494:pharmacology; D004027:Diencephalon / Q000187:drug effects*; D004298:Dopamine / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011955:Receptors, Drug; D013739:Testosterone / Q000097:blood*
D011955:Receptors, Drug; D013739:Testosterone; D001058:Apomorphine; D004298:Dopamine
Dofaminovye retseptory promezhutochnogo mozga, sviazannye a éndokrinnoĭ funktsieĭ gipofizarno-semennikovoĭ sistemy