[Analysis of the mitotic activity of the lymphoid cells of the thymus in relation to age].
The mitotic activity of lymphoid cells of the thymus was studied separately in the subcapsule zone of the cortical substance, cortical substance and medullary substance of newborn, 21-day, 3-, 4-month and 12-month-old mice. In addition to counting mitoses (MA%) histograms of the organ lobes were drawn with exact localization of mitoses of dividing cells. The greatest index of mitotically dividing cells was noted in the subcapsule zone of newborns and 21-day-old mice (5,2+/-0,9 and 4,7+/-0,5). After sex maturation the mitotic activity considerably decreased but in 3-, 4- and 12-month-old mice, the mitotic coefficient of lymphoid cells also retained rather high level (2,6+/-0,3 and 2,1+/-0,2) though processes of involution took place in their thymus.
D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology; D008297:Male; D051379:Mice; D008938:Mitosis; D008940:Mitotic Index; D013950:Thymus Gland / Q000502:physiology*
Analiz mitoticheskoĭ aktivnosti limfoidnykh kletok timusa v vozrastnom aspekte