[Study of the metabolic activity of a continuous line of human embryo lung cells infected with oncornavirus type D].
The metabolic activity of human embryo lung cell cultures infected with oncornavirus D obtained from the liquid phase of HEp-2 cultures was studied. In the infected cells of the 2nd passage there was 2-3 fold stimulation of biosynthesis of DNA, RNA and protein. Stimulation of DNA synthesis was particularly marked. In cells of uninfected cultures grown in the presence of a carcinogen, some stimulation of DNA, RNA and protein synthesis was observed. However no considerable differences were observed in the metabolic activity of cells in the infected cultures grown with or without carcinogen.
D002460:Cell Line; D004247:DNA / Q000096:biosynthesis*; D006801:Humans; D008168:Lung / Q000196:embryology; D008748:Methylcholanthrene / Q000494:pharmacology; D009858:Oncogenic Viruses / Q000254:growth & development*; D014176:Protein Biosynthesis; D012313:RNA / Q000096:biosynthesis*; D014779:Virus Replication
D008748:Methylcholanthrene; D012313:RNA; D004247:DNA
Izuchenie metabolicheskoi aktivnosti perevivaemol linii kletok legkogo embriona cheloveka, infitsirovannykh onkornavirusom tipa D