[Effect of a decrease in viscosity on myocardial blood flow and function in myocardial infarct].
In 5 dogs the effect of a decrease in blood viscosity on myocardial blood flow (radioactive microspheres) and left ventricular function (Sarnoff curves) following ligation of the left anterior descending coronary artery was tested. Moderate anaemia produced a significant increase in coronary blood flow to the total left ventricle (+ 100%) and to the ischemic area (+ 400%). Depressed left ventricular function after coronary ligation alone was restored when blood viscosity was lowered only slightly. Severe anaemia further increased coronary blood flow but left ventricular function worsened.
D000818:Animals; D001809:Blood Viscosity; D003326:Coronary Circulation; D004285:Dogs; D006400:Hematocrit; D009203:Myocardial Infarction / Q000503:physiopathology*; D010101:Oxygen Consumption; D012039:Regional Blood Flow
Der Effekt einer Viskositätserniedrigung auf die myocardiale Durchblutung und Funktion beim Infarktherzen