title: Prompt regression of cystic vaginal adenosis following cessation of oral contraceptive therapy.
abstract: Cystic vaginal adenosis was diagnosed in a 31-year-old woman. This lesion regressed promptly following the cessation of an oral contraceptive (Ovulen-21) which had been used continuously for 5 years. The temporal relationship between discontinuation of contraceptive treatment and the regression strongly suggests that the medication played a causal role in producing cystic vaginal adenosis. A possible mechanism may have been the stimulation of quiescent glands to growth and cystic dilatation, which finally produced a lesion associated with clinical symptoms.
mesh_terms: D000328:Adult; D003276:Contraceptives, Oral / Q000009:adverse effects*; D005260:Female; D006801:Humans; D014623:Vaginal Diseases / Q000139:chemically induced* / Q000473:pathology
chemical_list: D003276:Contraceptives, Oral