[Inhibiting effect of sodium dodecylsulphate on DNase of animal tissues].
The activity of DNases in homogenates of the spleen, thyroid gland and intestine mucosa of rats as well as in solution of purified pancreatic DNase was studied as affected by sodium dodecylsulphate. Dodecylsulphate has an inhibitory effect on all the studied DNase. The effect grows up to complete inhibition of DNases with an increase in the content of detergent in the incubation mixture from 0.5 to 5-10 mg/ml.
D000818:Animals; D003851:Deoxyribonucleases / Q000037:antagonists & inhibitors*; D004305:Dose-Response Relationship, Drug; D007413:Intestinal Mucosa / Q000187:drug effects / Q000201:enzymology; D009928:Organ Specificity; D010179:Pancreas / Q000187:drug effects / Q000201:enzymology; D051381:Rats; D012967:Sodium Dodecyl Sulfate / Q000494:pharmacology*; D013154:Spleen / Q000187:drug effects / Q000201:enzymology; D013961:Thyroid Gland / Q000187:drug effects / Q000201:enzymology
D012967:Sodium Dodecyl Sulfate; D003851:Deoxyribonucleases
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