title: [Convulsive mechanism of ketamine anesthesia].
abstract: Experimental studies conducted on rabbits enabled the authors to reveal the central mechanism of the ketamine effect. Based on the experimental data obtained, the authors elaborated and used clinically the method of balance ketamine anesthesia consisting in a combination of ketamine with antispasmatic drugs: seduxen and mydocalm. This method of anesthesia is recommended for eliminating ketamine side effects.
mesh_terms: D000771:Anesthesia, Intravenous; D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects; D006801:Humans; D007649:Ketamine / Q000008:administration & dosage / Q000009:adverse effects* / Q000037:antagonists & inhibitors / Q000494:pharmacology; D010276:Parasympatholytics / Q000008:administration & dosage / Q000494:pharmacology; D011817:Rabbits; D012640:Seizures / Q000139:chemically induced* / Q000517:prevention & control
chemical_list: D010276:Parasympatholytics; D007649:Ketamine
vernacular_title: Sudorozhnyĭ mekhanizm razvitiia ketaminovoĭ anestezii