[A pharmacologic analysis of several adrenomimetic effects of serotonin].
Contractions of the isolated rat vas deferens in response to the addition of serotonin could be explained by the release of catecholamines from the nerve endings. As shown by the use of D-, M- and T-antagonists of serotonin (LSD-25, indocarb, typindole), symatholytic--bretilium, alpha-adrenolytic--droperidol and imipramine, this effect was not associated with the direct activation of serotonin- and adrenoreactive receptors.
D000818:Animals; D001949:Bretylium Compounds / Q000494:pharmacology; D004329:Droperidol / Q000494:pharmacology; D007099:Imipramine / Q000494:pharmacology; D008238:Lysergic Acid Diethylamide / Q000494:pharmacology; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology; D051381:Rats; D012701:Serotonin / Q000494:pharmacology*; D013566:Sympathomimetics; D014649:Vas Deferens / Q000187:drug effects* / Q000378:metabolism
D001949:Bretylium Compounds; D013566:Sympathomimetics; D012701:Serotonin; D008238:Lysergic Acid Diethylamide; D004329:Droperidol; D007099:Imipramine; D009638:Norepinephrine
Farmakologicheskiĭ analiz nekotorykh adrenomimeticheskikh éffektov serotonina