title: [Therapy of progressive scleroderma. Collagen-like protein in progressive scleroderma under D-penicillamine therapy].
abstract: The collagen-like-protein (CLP) in sera of patients with scleroderma (n = 20) and controls with (n = 25) this disease as well as in scleroderma-patients under treatment with D-penicillamine (DPA) was determined. The increase of collagen-like-protein roughly parallels the activity of the disease and secondly parallels the therapy. A relationship to collagen biosynthesis or metabolism is discussed.
mesh_terms: D001798:Blood Proteins / Q000378:metabolism*; D003094:Collagen / Q000096:biosynthesis / Q000097:blood*; D006801:Humans; D012595:Scleroderma, Systemic / Q000097:blood / Q000188:drug therapy*
chemical_list: D001798:Blood Proteins; D003094:Collagen
vernacular_title: Zur Therapie der progressiven Sklerodermie. Das Collagen-like-Protein bei der progressiven Sklerodermie unter D-Penicillamin-Therapie