Effect of DDT on the free amino acid pool of brain and kidney in guinea-pigs.
Free amino acid composition of brain and kidney of guinea-pig showed significant decrease after repeated exposure of skin to P-P1 DDT. Gamma amino butyric acid of the brain and proline, tyrosine and valine of kidney disappeared completely. The remaining amino acids showed a marked depletion.
D000596:Amino Acids / Q000378:metabolism*; D000613:Aminobutyrates / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism*; D003553:Cystine / Q000378:metabolism; D003634:DDT / Q000506:poisoning*; D003864:Depression, Chemical; D005260:Female; D006168:Guinea Pigs; D007668:Kidney / Q000378:metabolism*; D011392:Proline / Q000378:metabolism; D014443:Tyrosine / Q000378:metabolism; D014633:Valine / Q000378:metabolism
D000596:Amino Acids; D000613:Aminobutyrates; D014443:Tyrosine; D003553:Cystine; D011392:Proline; D003634:DDT; D014633:Valine