[Method of evaluating the synaptic input to a single mesencephalic neuron].
The mathematical model of the spike activity of a neuron with synaptic input from many other neurons [1], describes adequately the firing of 5 from 7 neurons in the tegmentum of mesencephalic cat and changes of their activity evoked by glutamate iontophoresis. For these 5 neurons the estimates of the PSPs' average frequency of the threshold depolarization and of the constant decay of the EPSP were received. For different neurons the values of these parameters are 4--100 KHz, 100--800 average unitary EPSPs and 4--30 msec correspondingly. The stationary value of the average membrane potential (SVAMP) in all 5 neurons was removed significantly from the resting potential toward the threshold potential. SWAMP could be changed by the glutamate iontophoresis in such a degree to overlap the threshold potential.
D000818:Animals; D002415:Cats; D008564:Membrane Potentials; D008636:Mesencephalon / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D013569:Synapses / Q000502:physiology*
Sposob otsenki sinapticheskogo pritoka k odinochnomu neĭronu srednego mozga