title: On the toxicity of procaine for pigs.
abstract: Procaine caused respiratory arrest in halothane-anaesthetized normal Landrace pigs at a dose of 4,2 - 8,2 mg/kg. In some cases death due to respiratory failure occurred after giving 10 - 13 mg/kg. Because of its toxicity in pigs procaine is unsuitable for treating the porcine malignant hyperthermia syndrome.
mesh_terms: D000769:Anesthesia, Inhalation / Q000662:veterinary; D000818:Animals; D004341:Drug Evaluation; D005334:Fever / Q000188:drug therapy; D006221:Halothane; D011343:Procaine / Q000633:toxicity*; D012119:Respiration / Q000187:drug effects*; D013552:Swine
chemical_list: D011343:Procaine; D006221:Halothane