[The effect of ouabain on the sugar receptor of the contact chemoreceptive sensilla of the fly Protophormia terraenovae].
Studies have been made on the inhibitory effect of ouabain solutions on bioelectrical activity of the labellar sensillae of flied. It was shown that 10(-2) M ouabain solution irreversibly inhibits the activity, where as 10(-3) and 10(-4) M concentrations decrease the frequency of impulses within 40-60 min. Ouabain solution is a specific stimulator of the sugar receptor of the sensillae with a threshold of 10(-7) M; in combination with 0.2 M glucose, it inhibits impulse activity with the first 200 msec of stimulation. The effect is observed in a narrow zone of ouabain concentrations, with a maximum approximately at 10(-4) M. Differences between the effects of the inhibitor at the vicinity of the onset of generator potential and those in the impulse activity zones on the membrane of the sensory cell are suggested.
D000818:Animals; D002628:Chemoreceptor Cells / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D004175:Diptera / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D008854:Microscopy, Electron; D010042:Ouabain / Q000494:pharmacology*; D013395:Sucrose / Q000502:physiology; D013649:Taste
D013395:Sucrose; D010042:Ouabain
Deĭstvie oubaina na sakharnyĭ retseptor kontaktnoĭ khimoretseptornoĭ sensilly mukhi Protophormia terraenovae