Instant selective arterial occlusion with isobutyl 2-cyanoacrylate.
Isobutyl 2-cyanoacrylate (IBC) delivered selectively in small doses produced immediate occlusion of the injected arteries in dogs without significant undesired sequelae. In one patient, pelvic hemorrhage was promptly stopped by a similar technique. In another patient, who was on chronic renal dialysis and judged too ill for nephrectomy, IBC occluded both renal arteries and terminated a life-threatening renal protein loss.
D000328:Adult; D000818:Animals; D001158:Arteries; D002015:Bucrylate / Q000627:therapeutic use*; D003487:Cyanoacrylates / Q000627:therapeutic use*; D004285:Dogs; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005921:Glomerulonephritis / Q000628:therapy; D006801:Humans; D014592:Uterine Hemorrhage / Q000628:therapy
D003487:Cyanoacrylates; D002015:Bucrylate