title: Primary C-cell hyperplasia within a nodule of thyroid isthmus.
abstract: The electron microscopy method was used to study one case of primary C-cell hyperplasia in 'hot' thyroid nodule of isthmus. Hyperplasia of the light form of C cells was found within nodule tissue. It suggests that C-cell hyperplasia within the nodule as well as in normal thyroid tissue plays a role preceding C-cell carcinoma.
mesh_terms: D000236:Adenoma / Q000473:pathology*; D000328:Adult; D002277:Carcinoma / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D006801:Humans; D008297:Male; D013961:Thyroid Gland / Q000648:ultrastructure*; D013964:Thyroid Neoplasms / Q000473:pathology*