Comparative studies on the behaviour of the plasmatic clotting system and platelet function in surgically treated cancer patients.
By measuring 18 functional parameters of blood coagulation the dynamic pattern of pre- and postoperative blood coagulation was studied in a total of 43 patients with primarily operable solid tumours. The results were compared with those obtained in patients having benign diseases in the same anatomical regions. Results were discussed preferably from the tumourbiological point of view. Changes of blood coagulation occuring in operated cancer patients with benign diseases. Compensatory processes operating in the haemostatic system provide a well balanced coagulation even in cancer patients. Patients with gastric cancer having low adenine nucleotide levels in platelets had a significantly higher risk to die postoperatively than those with normal levels. This indicates metabolic disorder on cellular levels than haemostatic dysfunctions.
D000244:Adenosine Diphosphate / Q000097:blood; D000255:Adenosine Triphosphate / Q000097:blood; D000328:Adult; D000368:Aged; D001777:Blood Coagulation; D001792:Blood Platelets / Q000378:metabolism; D001943:Breast Neoplasms / Q000097:blood; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood* / Q000601:surgery; D010974:Platelet Aggregation; D013274:Stomach Neoplasms / Q000097:blood
D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate