[Analysis of the phenomenon of lowered cerebral blood flow in cats under prolonged intracarotid microinfusion of vasodilator substances].
In 27 anesthetized cats, continual intracarotid microinfusion of 0.04% solution of noshpa first increased CBF by 12-76% and then CBF gradually decreased to the normal level and even 14% below it. There was no strict correlation between the degree of lowering CBF and the level of blood pressure, pH, pCO2, blood viscosity, or level of vasopressor substances. No signs of brain tissue oedema was found.
D000818:Animals; D001593:Benzyl Compounds / Q000494:pharmacology; D001783:Blood Flow Velocity; D001794:Blood Pressure / Q000187:drug effects; D001809:Blood Viscosity / Q000187:drug effects; D001929:Brain Edema / Q000139:chemically induced; D002339:Carotid Arteries; D002415:Cats; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D007546:Isoquinolines / Q000494:pharmacology; D009125:Muscle Relaxants, Central; D010208:Papaverine / Q000031:analogs & derivatives*; D010313:Partial Pressure; D014665:Vasodilator Agents / Q000494:pharmacology*
D001593:Benzyl Compounds; D007546:Isoquinolines; D009125:Muscle Relaxants, Central; D014665:Vasodilator Agents; D010208:Papaverine
K analizu fenomena umen'sheniia mozgovogo krovotoka u koshek pri dlitel'noĭ vnutrikarotidnoĭ mikroinfuzii sosudorasshiriaiushchikh veshchestv