Treatment of chronic glomerulonephritis with a combination of indomethacin and cyclophosphamide.
33 cases of chronic glomerulonephritis who responded unsatisfactorily to treatment with indomethacin alone were treated in addition with a low dose of cyclophosphamide. The five patients with focal glomerulosclerosis responded poorly. The remaining 28 patients showed a statistically significant improvement in renal function and proteinuria.
D003404:Creatinine / Q000378:metabolism; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005921:Glomerulonephritis / Q000188:drug therapy*; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D011507:Proteinuria; D013997:Time Factors
D003520:Cyclophosphamide; D003404:Creatinine; D007213:Indomethacin