title: [Evaluation of reliable pituitary suppression therapy through varying thyroid hormone dosage following total thyroidectomy due to a differentiated thyroid carcinoma].
abstract: The reliability of pituitary suppression by administration of 1-thyroxin (t4) or a combination of thyroxin and triiodothyronin (t3) of variable dosage following radical surgery for thyroid cancer in 13 patients was investigated by means of TRH-test and measurement of serum hormone levels. In contrary to generally applied higher doses the results were able to demonstrate that 0.2 to 0.3 mg 1-thyroxin is a sufficient dosage for a complete suppression of TSH-stimulation. In the presence of obviously more side effects the treatment with a combination of t4 and t3 is not of any advantage.
mesh_terms: D002277:Carcinoma / Q000601:surgery*; D006801:Humans; D010902:Pituitary Gland / Q000187:drug effects; D013960:Thyroid Function Tests; D013964:Thyroid Neoplasms / Q000601:surgery*; D013965:Thyroidectomy; D013972:Thyrotropin / Q000037:antagonists & inhibitors*; D013974:Thyroxine / Q000008:administration & dosage*
chemical_list: D013972:Thyrotropin; D013974:Thyroxine
vernacular_title: Uberprüfung der verlässlichen hypophysären Suppressionstherapie durch unterschiedliche Schilddrüsenhormondosierungen nach totaler Thyreoidektomie wegen eines differenzierten Schilddrüsen-Karzinoms