title: Modification of the contractile responses of rabbit mammary strips to oxytocin by prostaglandin E1.
abstract: PGE1 administration to isolated strips from pregnant and lactating rabbit mammary gland resulted in different effects on oxytocin-induced contractions. In strips from pregnant animals, oxytocin action was enhanced; in those from lactating animals, it was reduced and threshold doses for oxytocin were markedly higher.
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005260:Female; D066298:In Vitro Techniques; D007774:Lactation; D008321:Mammary Glands, Animal / Q000187:drug effects* / Q000502:physiology; D009119:Muscle Contraction / Q000187:drug effects; D010121:Oxytocin / Q000494:pharmacology*; D011247:Pregnancy; D011458:Prostaglandins E / Q000494:pharmacology*; D011817:Rabbits
chemical_list: D011458:Prostaglandins E; D010121:Oxytocin