Thin layer chromatographic screening test for urinary 3-methoxy-4-hydroxyphenylethylene glycol; results from cases of secreting neuroblastoma.
A thin layer chromatographic screening test is reported for the determination of urinary 3-methoxy-4-hydroxyphenylethylene glycol. The concentration in any sample is estimated by visual comparison with a range of 10 standards of different concentrations. The urines of five children with positively diagnosed hormonally active neuroblastoma showed values of 19.0-32.4 mg 3-methoxy-4-hydroxyphenylethylene glycol/g creatinine, whereas control urines contained only 0.4-1.7 mg/g creatinine.
D002648:Child; D002675:Child, Preschool; D002855:Chromatography, Thin Layer / Q000379:methods; D003404:Creatinine / Q000652:urine; D006018:Glycols / Q000652:urine*; D006801:Humans; D007223:Infant; D008734:Methoxyhydroxyphenylglycol / Q000652:urine*; D009369:Neoplasms / Q000652:urine; D009447:Neuroblastoma / Q000652:urine*
D006018:Glycols; D008734:Methoxyhydroxyphenylglycol; D003404:Creatinine