title: Influence of copper intrauterine contraceptive devices (Cu-7-IUD) on the menstrual blood-loss.
abstract: In a series of 43 healthy women menstrual blood loss was determined before and after insertion of copper IUD (Gravigard). The menstrual blood loss before insertion was compared with the blood loss 1, 2, 3, 4, 5, 6, 7 and 12 months after insertion. An increase amounting to approximately 20 ml per period without significant variations during the study was recorded. No significant influence upon serum iron and TIBC was found in 15 of the subjects selected by random. Compared with plastic IUD's the tested copper IUD causes a less pronounced increase of the menstrual blood loss. The menstrual blood loss in a small group of women with menorrhagia was determined before and up to 5 months after insertion of copper IUD. No aggravation of the menorrhagia was however recorded in this group.
mesh_terms: D001769:Blood; D003300:Copper; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007434:Intrauterine Devices; D007501:Iron / Q000097:blood; D008595:Menorrhagia / Q000097:blood; D008598:Menstruation; D013997:Time Factors
chemical_list: D006454:Hemoglobins; D003300:Copper; D007501:Iron