A double-blind trial of bupivacaine (Marcain) and etidocaine (Duranest) in extradural block for surgical induction of labour.
A double-blind randomized trial was conducted to compare etidocaine, the new local anaesthetic agent, with bupivacaine. One hundred patients were each given a single dose of one of the drugs during the surgical induction of labour. The results showed that etidocaine had a quicker onset of action than bupivacaine, but that its duration of action was shorter, and that it produced a greater degree of muscle weakness. No differences were noted in the side effects of the two drugs.
D000083:Acetanilides / Q000031:analogs & derivatives; D000767:Anesthesia, Epidural; D000773:Anesthesia, Obstetrical; D002045:Bupivacaine / Q000008:administration & dosage / Q000009:adverse effects; D005041:Etidocaine / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D007751:Labor, Induced; D011247:Pregnancy
D000083:Acetanilides; D005041:Etidocaine; D002045:Bupivacaine