[The relationship between temperature adaptation and the effect of noradrenaline on central control of thermoregulation].
In rats cold--adapted (1--3 degrees C) or warmth--adapted (26--28 degrees C) for 4--5 weeks, the body temperature, oxygen uptake, electric muscle activity were continuously recorded before and after intraventricular injection of noradrenaline (NA) at a total volume of 5--8 mcl. At the ambient temperature of 25 degrees C, extremely small doses (5--8 mcg) of NA raised the body temperature due to shivering. Injections of NA were more effective in the cold--adapted rats. Injections of NA at a low ambient temperature (10 degrees C) evoked greater thermoregulatory responses in the warmth-adapted rats.
D000222:Adaptation, Physiological / Q000187:drug effects*; D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D001833:Body Temperature Regulation / Q000187:drug effects*; D003080:Cold Temperature; D004594:Electrophysiology; D006358:Hot Temperature; D007031:Hypothalamus / Q000187:drug effects*; D007276:Injections, Intraventricular; D008297:Male; D009132:Muscles / Q000502:physiology; D009638:Norepinephrine / Q000494:pharmacology*; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats; D012621:Seasons
D009638:Norepinephrine
Effekt noradrenalina na tsentral'noe upravlenie termoreguliatsieĭ v sviazi s temperaturnoĭ adaptatsieĭ