[O2 pressure on liver surface following portacaval anastomosis and administration of vasoactive substances in dogs with normal livers].
1) Following acute portocaval anastomosis in healthy dog liver tissue - pO2 drops by 23%, an extent regulary occuring in hour long laparotomy. 2) Intravenous octapressin lowers splanchnic blood flow, concomitantly liver blood-flow and tissue -pO2 is decreased. 3) In contrast to octapressin orciprenalin improves liver blood-flow and tissue-pO2. 4) By shunting of arterial blood through the gut norepinephrine causes a rapid and lasting elevation of liver tissue-pO2.
D000818:Animals; D004285:Dogs; D005260:Female; D008099:Liver / Q000187:drug effects*; D008297:Male; D009921:Metaproterenol / Q000494:pharmacology; D010100:Oxygen / Q000032:analysis*; D010313:Partial Pressure; D011167:Portacaval Shunt, Surgical; D011168:Portal System / Q000187:drug effects; D013499:Surface Properties; D014662:Vasoconstrictor Agents / Q000494:pharmacology; D014665:Vasodilator Agents / Q000494:pharmacology
D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents; D009921:Metaproterenol; D010100:Oxygen
Der O2-Druck an der Leberoberfläche nach portocavaler Anastomose und nach Gabe vasoaktiver Substanzen beim lebergesunden Hund