title: Morphine concentrations in plasma after intramuscular administration.
abstract: Plasma morphine concentrations were measured by a radioimmunoassay technique following the intramuscular administration of morphine 0.2 mg/kg body weight as a preoperative medication. The highest plasma concentrations were obtained about one hour after the administration of the drug and there was a sevenfold variation in these concentrations between individuals. For 24 hr following a single intramuscular injection, there was measurable quantities of morphine or its metabolites in the plasma. In healthy patients who were undergoing a therapeutic abortion, there was no correlation between pain relief and the plasma concentration of morphine.
mesh_terms: D000032:Abortion, Therapeutic; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D011247:Pregnancy; D012601:Scopolamine / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D012601:Scopolamine