[Study of the possibility of using penicillin and a specific globulin for treating the anthracic infectious process in an irradiated organism].
Comparative efficacy of the specific globulin and penicillin in the treatment of Siberia ulcer infection was studied on 160 guinea pigs and 400 albino mice irradiated with Co60 gama-rays in sublethal doses. It was found that penicillin preserved its efficiency, while the curative effect of the specific globulin significantly decreased in the irradiated animals.
D000818:Animals; D000881:Anthrax / Q000188:drug therapy*; D001428:Bacterial Vaccines / Q000008:administration & dosage; D003037:Cobalt Radioisotopes; D004353:Drug Evaluation, Preclinical; D005916:Globulins / Q000627:therapeutic use*; D006168:Guinea Pigs; D051379:Mice; D010406:Penicillins / Q000627:therapeutic use*; D011833:Radiation Injuries, Experimental / Q000150:complications*; D013997:Time Factors
D001428:Bacterial Vaccines; D003037:Cobalt Radioisotopes; D005916:Globulins; D010406:Penicillins
Izuchenie vozmozhnosti primeneniia penitsillina i spetsificheskogo globulina dlia lecheniia sibireiazvennogo infektsionnogo protsessa v obluchennom organisme