Chenodeoxycholic acid inhibits increased cholesterol and cholestanol synthesis in patients with cerebrotendinous xanthomatosis.
D000125:Achilles Tendon / Q000378:metabolism*; D000328:Adult; D000438:Alcohols / Q000378:metabolism; D001646:Bile / Q000187:drug effects / Q000378:metabolism; D001647:Bile Acids and Salts / Q000378:metabolism; D002635:Chenodeoxycholic Acid / Q000494:pharmacology*; D002784:Cholesterol / Q000378:metabolism*; D005260:Female; D006801:Humans; D006903:Hydroxymethylglutaryl CoA Reductases / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000378:metabolism*; D013261:Sterols / Q000378:metabolism*; D014973:Xanthomatosis / Q000378:metabolism*
D000438:Alcohols; D001647:Bile Acids and Salts; D013261:Sterols; D002635:Chenodeoxycholic Acid; D002784:Cholesterol; D006903:Hydroxymethylglutaryl CoA Reductases