[Does estradiol act in a unique way during progestation in the female rat? I. Uptake and retention of estradiol 17beta in the uterus of castrated rats under the influence of uterine distension].
In castrated female rats, uterine distension resulted in an increased uptake of tritiated oestradiol within the period studied (from 10 minutes to 24 hours after distension), whereas progesterone 14C incorporation was not increased. Using cold hormones (progesterone or oestradiol) before injection of radioactive ones, wer were able to demonstrate the specificity of this uptake 3.5 hours or 24 hours after initiation of distension. These results suggested that the oestradiol receptor may be synthetized without direct hormonal action. They are discussed with regard to oestradiol action, particularly during progestati-n and at the time of ovum implantation.
D000818:Animals; D002369:Castration; D004958:Estradiol / Q000378:metabolism / Q000502:physiology*; D005260:Female; D011374:Progesterone / Q000378:metabolism; D051381:Rats; D013997:Time Factors; D014599:Uterus / Q000378:metabolism / Q000502:physiology*
D011374:Progesterone; D004958:Estradiol
L'oestradiol intervient-il selon un mode d'action unique au cours de la progestation chez la ratte? I.--Incorporation et retention d'oestradiol 17beta dans l'uterus des rattes castrées sous l'action de la distension uterine