title: Villous papilloma of the colon and rectum. Part II. A follow-up study of 213 patients.
abstract: A follow-up study of 213 patients with colorectal villous papillomas was performed to assess different methods of treatment and the prognostic value of several factors. Recurrences appeared in 26%. Segmental resection of the intestine gave no recurrences. The choice of surgical method had little or no influence on the 5-year survival rate. The 5-year crude survival rate for the whole series was 61% with a relative survival of 80%. The larger tumours had the poorest 5-year survival rates. Tumours with invasive carcinoma in the villous papilloma had a crude 4-year survival of 16% whereas tumours which did not originally show invasive features had a 5-year crude survival rate of 68%. Of the whole series 48 patients (22%) eventually died from colorectal cancer. It is possible that the invasive character of the tumour had been missed originally so thorough microscopic examination of the whole tumour is essential.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D003110:Colonic Neoplasms / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary; D010212:Papilloma / Q000401:mortality / Q000601:surgery*; D012004:Rectal Neoplasms / Q000401:mortality / Q000601:surgery*; D012189:Retrospective Studies; D012737:Sex Factors