The use of discriminatory values for thyroid uptake and free thyroxine index.
The distributions of 4 hour 132I neck uptake and 20 minute 99mTcO4 thyroid uptake in euthyroid patients were found to conform closely to a log normal distribution, from which a statistical normal range may be obtained. More accurate discriminatory values for determining thyroid status may be established by plotting intersecting distribution curves for hypo-, hyper- and euthyroid groups. Subdivision by age and by the presence or absence of a palpable thyroid reveals considerable variations from which a series of more accurate discriminatory values may be established for these subgroups. For Free Thyroxine Index (T4RT3 index) more accurate discriminatory values were also obtained by similar methods; while no significant variations related to age or palpable thyroid were observed, subdivision of the patients into two groups referred as suspected hypothyroidism and suspected hyperthyroidism yielded a further small improvement in accuracy.
D000328:Adult; D000367:Age Factors; D000368:Aged; D002850:Chromatography, Gel; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D013223:Statistics as Topic; D013667:Technetium; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000378:metabolism; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D007457:Iodine Radioisotopes; D014284:Triiodothyronine; D013667:Technetium; D013974:Thyroxine