The effect of phencyclidine anaesthesia on the blood chemistry and haematology of the chacma baboon (Papio ursinus).
Blood was collected from 14 baboons 3 - 5 min, 30 min and 60 min after the intramuscular injection of phencyclidine at a dosage rate of 1,5 mg/kg body mass. The determination of blood chemistry and haematology was then undertaken. An abrupt decrease in total plasma protein occurred after the injection of phencyclidine but thereafter it remained at approximately the same level. The sodium, potassium, chloride and cholesterol remained practically unaltered throughout. A significant decrease occurred in the blood urea level. The blood sugar value showed a highly significant decrease over the first 30 min period and less over the second 30 min period. Plasma enzyme activity and corticosteroid levels did not show marked alterations. Marked and significantly lowered values occurred in white blood cell count, erythrocyte count, haemoglobin concentration and haematocrit level but these values returned to within normal limits at 60 min.
D000768:Anesthesia, General / Q000662:veterinary*; D000818:Animals; D001773:Blood Cells / Q000187:drug effects; D001774:Blood Chemical Analysis; D001786:Blood Glucose / Q000378:metabolism; D001798:Blood Proteins / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D004573:Electrolytes / Q000097:blood; D004798:Enzymes / Q000097:blood; D005260:Female; D007103:Immobilization; D008297:Male; D010215:Papio / Q000097:blood*; D012737:Sex Factors
D001786:Blood Glucose; D001798:Blood Proteins; D004573:Electrolytes; D004798:Enzymes; D002784:Cholesterol