Skeletal metastases from retinoblastoma.
Four patients with skeletal metastases from retinoblastomas are presented. Radiologically, the metastases showed periosteal new bone formation and permeative-type bone destruction, particularly involving the long bones of the extremities, and they tended to be bilateral. The metastases resembled those of neuroblastoma and, to a lesser extent, medulloblastoma. The relationship between these three tumors is discussed.
D001846:Bone Development; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008527:Medulloblastoma / Q000473:pathology; D009362:Neoplasm Metastasis; D009447:Neuroblastoma / Q000473:pathology; D011859:Radiography; D012175:Retinoblastoma / Q000000981:diagnostic imaging / Q000473:pathology*