title: Potato inhibitors of intrinsic prothrombin activators.
abstract: The potato protease inhibitors inhibit intrinsic prothrombin activators and trypsin activation of prothrombin. The inhibitors 5a and 5b are responsible for the intrinsic prothrombin activator inhibition. This inhibition is progressive. No inhibition by these inhibitors of tissue thromboplastin activation of prothrombin or thrombin activity was observed.
mesh_terms: D000818:Animals; D004285:Dogs; D004789:Enzyme Activation / Q000187:drug effects; D010944:Plants / Q000201:enzymology*; D011480:Protease Inhibitors; D011516:Prothrombin / Q000096:biosynthesis*; D013925:Thromboplastin; D014361:Trypsin Inhibitors
chemical_list: D011480:Protease Inhibitors; D014361:Trypsin Inhibitors; D011516:Prothrombin; D013925:Thromboplastin