title: [The activity and isoenzyme spectrum of lactate dehydrogenase in tissues of rats of different ages].
abstract: Age alterations of the total activity and isoenzyme spectrum of lactate dehydrogenase were observed in rat skeletal muscles, liver and heart. In the aged animals the total activity of LDH was increased in skeletal and heart muscles. In the skeletal muscles and liver tissue of the aged rats content of M-subunits the LDH and the content of LDH-5 was increased. In the heart muscle content of H-subunits, LDH-1 and LDH-2 was increased as compared with adult and growing rats.
mesh_terms: D000375:Aging; D000818:Animals; D006321:Heart / Q000254:growth & development; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008099:Liver / Q000201:enzymology / Q000254:growth & development; D024510:Muscle Development; D009132:Muscles / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D009928:Organ Specificity; D051381:Rats
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
vernacular_title: Aktivnost' i izofermentnyĭ spektr laktatderidrogenazy v tkaniakh krys raznogo vozrasta