Mycotic granuloma caused by Phialophora repens.
This is the first reported infection by the saprophytic fungus, Phialophora repens. The infection was a solitary granulomatous nodule in the scalp of a Zaïrian man with advanced lepromatous leprosy. The patient was being treated by long-term prednisolone therapy. In tissue sections there were nonpigmented microcolonies composed of irregularly branched septate hyphae. A darkly pigmented fungus was isolated on Sabouraud's medium. The mycologic features of the etiologic agent were typical of P. repens. The infection was treated successfully by excision of the nodule.
D000328:Adult; D006099:Granuloma / Q000150:complications / Q000209:etiology* / Q000382:microbiology; D006801:Humans; D007918:Leprosy / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D009181:Mycoses / Q000150:complications / Q000209:etiology* / Q000382:microbiology; D010676:Phialophora / Q000166:cytology / Q000302:isolation & purification; D011239:Prednisolone / Q000627:therapeutic use
D011239:Prednisolone