title: [Ultrastructure of the cells of the peripheral blood in experimental lead poisoning].
abstract: In rabbits exposed to lead poisoning electron microscopy revealed the presence in reticulocytes and erythrocytes of differently sized vacuoles, an amassment of ferritin granules in the mitochondria along with autophaging vacuoles; leucocytes evidenced turgescence of the mitochondria, up to and including their destruction and emptiness; the blood platelets showed an abundant vacuolization with disordered distribution of the serotonin and glycogen granules. The above changes become most spectacular on the 7-21st day after poisoning and by the 50th day they are encountered but in isolated cells.
mesh_terms: D000818:Animals; D001773:Blood Cells / Q000187:drug effects* / Q000648:ultrastructure; D001792:Blood Platelets / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004912:Erythrocytes / Q000648:ultrastructure; D005293:Ferritins; D006003:Glycogen; D007855:Lead Poisoning / Q000097:blood*; D007962:Leukocytes / Q000648:ultrastructure; D008928:Mitochondria / Q000648:ultrastructure; D011817:Rabbits; D012156:Reticulocytes / Q000648:ultrastructure; D012701:Serotonin; D013997:Time Factors; D014617:Vacuoles / Q000648:ultrastructure
chemical_list: D012701:Serotonin; D006003:Glycogen; D005293:Ferritins
vernacular_title: Ul'trastruktura kletok perifericheskoĭ krovi pri éksperimental'noĭ svintsovoĭ intoksikatsii