title: [Exhalation diagnosis with C14 tagged compounds, methods and results].
abstract: The method and results of the 14C exhalation test for metabolic studies are presented. In patients under radiotherapy for malignant diseases (we consider radiotherapy to be a well defined metabolic disturbance), studies with 14C-carboxyl triglycerides, with 14C-glycincholate, with 14C-histidine and with 14C-uridyl reveal the extent of the metabolic changes and also how long it would take to return to the normal state. It is not yet well understood why a disturbace of glycincholate absorption persists for years after radiotherapy of the pelvis. The method can also be employed in gastroenterology (absorption of bile salts) and in assessing an anabolic or catabolic state as af function of thyroid hormone. Further metabolic tests for radiobiologic evaluations are in progress.
mesh_terms: D001647:Bile Acids and Salts / Q000378:metabolism; D002250:Carbon Radioisotopes; D002952:Citric Acid Cycle; D005227:Fatty Acids / Q000378:metabolism; D006639:Histidine / Q000378:metabolism; D006801:Humans; D008659:Metabolic Diseases / Q000175:diagnosis* / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects*; D014280:Triglycerides / Q000378:metabolism; D014542:Uridine Monophosphate / Q000378:metabolism
chemical_list: D001647:Bile Acids and Salts; D002250:Carbon Radioisotopes; D005227:Fatty Acids; D014280:Triglycerides; D006639:Histidine; D014542:Uridine Monophosphate
vernacular_title: Exhalationsdiagnostik mit 14C-markierten Verbindungen, Methode und Resultate