Amino acid pattern in plasma before and after jejuno-ileal shunt operation for obesity.
The amino acid pattern in plasma was studied in a reference group (n=26) and in three groups of massive obese subjects (n=9, 8, and 9 respectively) before and at intervals after jejuno-ileostomy. The obese subjects had preoperatively an amino acid pattern significantly different from that in the reference group. The concentrations of lysine, tyrosine, 1/2 cystine, and glutamic acids were higher, and aspargin, glutamine, serine, and glycine were lower than in the reference group. During the post-operative period the amino acid pattern changed significantly; thus serine, glycine, and taurine increased and valine, lysine, leucine, tryptophan, thyrosine, 1/2 cystine, and citrulline decreased. The amino acid pattern in the obese group with the longest post-operative observation time and a stable body weight differed significantly from that in the reference group only with regard to a low valine concentration and high concentration of taurine and glutamatic acid.
D000328:Adult; D000596:Amino Acids / Q000097:blood*; D001835:Body Weight; D006801:Humans; D007082:Ileum / Q000601:surgery*; D007583:Jejunum / Q000601:surgery*; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000628:therapy*; D011446:Prospective Studies; D013997:Time Factors
D000596:Amino Acids