Laboratory investigations on pigs with the new anthelmintic fenbendazole.
The efficacy of fenbendazole was investigated in piglets infected artificially with Hyostrongylus rubidus and Oesophagostomum spp. After administration of 3.5 mg/kg, five-day-old stages of H rubidus were reduced by 72.5 per cent; an effect of 78.4 per cent, 96.0 per cent and 100 per cent was achieved against five-day-old, 16-day-old and 42-day-old stages, respectively, of H rubidus using a dose of 5 mg/kg. A 55 per cent effect was obtained against five-day-old stages after the administration of 3.5 mg/kg. A dose of 5 mg/kg reduced five-day-old, 16-day-old and 42-day-old stages of Oesophagotomum spp by 72.6 per cent, 44 per cent and 100 per cent respectively.
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D002219:Carbamates / Q000627:therapeutic use*; D009349:Nematode Infections / Q000662:veterinary*; D009814:Oesophagostomiasis / Q000188:drug therapy / Q000662:veterinary; D013552:Swine; D013553:Swine Diseases / Q000188:drug therapy*; D014252:Trichostrongyloidiasis / Q000188:drug therapy / Q000662:veterinary
D000871:Anthelmintics; D001562:Benzimidazoles; D002219:Carbamates