title: Incontinentia pigmenti and defective neutrophil chemotaxis.
abstract: A child with incontinentia pigmenti and chronic erythema multiforme had recurrent bacterial infections. Greatly elevated serum IgE was found. In addition, the patient's neutrophils showed essentially no chemotaxis toward Staphylococcus aureus, Escherichia coli, or Pseudomonas aeruginosa in either patient or control serum. Neutrophil phagocytosis and killing function were normal.
mesh_terms: D000328:Adult; D001424:Bacterial Infections / Q000150:complications; D002633:Chemotaxis; D002648:Child; D003165:Complement System Proteins / Q000032:analysis; D004892:Erythema Multiforme / Q000150:complications; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008214:Lymphocytes / Q000276:immunology; D009504:Neutrophils / Q000502:physiology*; D010859:Pigmentation Disorders / Q000097:blood* / Q000150:complications / Q000276:immunology; D012008:Recurrence; D013203:Staphylococcal Infections / Q000276:immunology
chemical_list: D007136:Immunoglobulins; D003165:Complement System Proteins