Treatment of Sydenham's chorea with a combination of L-dopa and a peripheral dopa decarboxylase inhibitor.
Two male patients suffering from Sydenham's chorea were treated with a combination of L-Dopa and a peripheral decarboxylase inhibitor. This treatment markedly reduced in one patient and totally suppressed in the other the abnormal involuntary movements present in this disease.
D000208:Acute Disease; D000293:Adolescent; D002230:Carbidopa / Q000627:therapeutic use*; D002819:Chorea / Q000134:cerebrospinal fluid / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D006719:Homovanillic Acid / Q000134:cerebrospinal fluid; D006801:Humans; D006834:Hydrazines / Q000627:therapeutic use*; D007980:Levodopa / Q000627:therapeutic use*; D008297:Male; D012008:Recurrence
D006834:Hydrazines; D007980:Levodopa; D002230:Carbidopa; D006719:Homovanillic Acid