[The lung and the metabolism of vasoactive substances].
The lung is the site of a number of reactions affecting vasoactive substances: hydrolysis of angiotensin I, bradykinin and ATP, occurring at the surface of endothelial cell; uptake and intracellular metabolism of 5-hydroxytryptamine and norepinephrine; and intracellular oxidation of prostaglandins. Mediators, including prostaglandins, histamine and SRS-A (slow reacting substance of anaphylaxis), can also be released from the lung. The possible implications of these recent findings are analysed.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000804:Angiotensin II / Q000378:metabolism*; D001920:Bradykinin / Q000378:metabolism*; D006636:Histamine Release; D006801:Humans; D008168:Lung / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism; D011453:Prostaglandins / Q000378:metabolism; D013189:SRS-A / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism
D011453:Prostaglandins; D013189:SRS-A; D000804:Angiotensin II; D012701:Serotonin; D000255:Adenosine Triphosphate; D001920:Bradykinin; D009638:Norepinephrine
Poumon et métabolisme des substances vasoactives