[Influence of acari of house dust in the tiology of infantile asthma].
We have studied 61 children with a previous diagnosis of a possible allergic disease showing clear symptoms in relation to the respiratory system (rhinitis, asthma, etc.). In all cases prick tests were carried out with house-dust extracts Dermatophagoides pteronyssinus, D. farinae, T. putrescentiae, A. siro and A. siro + Cheyletus spp. Commercial extracts (Bencard) were used for the former two; the remainder were prepared from the pure culture of the corresponding acari. The technique followed has been described separately. From the results obtained (see Table I) the following conclusions have been reached: 1. The acari of the Dermatophagoides species particularly D. peteronyssinus) are those mainly responsible for the antigenic capacity of house-dust studied in the geographic area of Barcelona and its surroundings. 2. A similarity but no antigenic identity exists between the antigenic extracts of D. pteronyssinus and D. farinae. 3. The many positive reactions shown by many patients to the various species of acari frequently found in house-dust are due not so much to the antigenic similarity of these acari as to the multiple sensitization or special condition of the individual person. 4. The allergens proceeding from different species of the Tyroglyphidae family, possibly possess a certain antigenic relationship. 5. Finally, it can be asserted that despite the important role played by the acari of the Dermatophagoides species among the different allergenic components of house-dust, it is the remaining acarian fauna present in this dust biocenosis that also has a distinct influence.
D000053:Acari; D000391:Air Microbiology; D001249:Asthma / Q000453:epidemiology / Q000209:etiology*; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D010372:Pediatrics; D011009:Pneumoconiosis / Q000150:complications* / Q000453:epidemiology; D013030:Spain
Influencia de los ácaros del polvo de casa en la etiología del asma infantil