Serum immunoglobulin levels in cancer patients. I. Serum immunoglobulins and primary tumor localization.
A comparison was made between the mean values of immunoglobulin IgG, IgA and IgM in patients sera in various primary localizations of malignant tumors. The values ranged generally above the upper limit stated for the so-called healthy population, the highest being in Ca of kidneys of Grawitz type, Ca laryngis and Co bronchogenes. In the IgG class higher values appeared mainly in Grawitz tumor, however, a certain elevated level with respect to the other groups of malignancies occurred also in Ca vesicae urinariae and in Ca bronchogenes, but the differences are without statistical significance. No changes were observed in the IgM group.
D000912:Antibodies, Neoplasm; D001943:Breast Neoplasms / Q000276:immunology; D002283:Carcinoma, Bronchogenic / Q000276:immunology; D005260:Female; D006689:Hodgkin Disease / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis; D007680:Kidney Neoplasms / Q000276:immunology; D007822:Laryngeal Neoplasms / Q000276:immunology; D008175:Lung Neoplasms / Q000276:immunology; D008297:Male; D009369:Neoplasms / Q000276:immunology*; D001749:Urinary Bladder Neoplasms / Q000276:immunology
D000912:Antibodies, Neoplasm; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins