[Participation of the neocortical and reticulo-hypothalamic apparatuses in the regulation of recurrent inhibition in the thalamic relay nucleus].
In acute experiments on cats a study was made into the development of the field potential of the recurrent inhibition wave (P-wave) in VPL in response to the stimulation of the somatosensory cortex. It has been found that high-frequency stimulation of the posterior medial hypothalamus results in the reduction of the thalamic P-wave brought about antidromically and in a decrease of the number of waves in the series. The effect of stimulation of the posterior hypothalamus on the processes of recurrent inhibition in the relay thalamus is to a great extent mediated through mechanisms of the branstem reticular formation. It has been shown that the dynamics of amplitude characteristics of primary sensory responses in the VPL depends on the phases of development of P-wave in the nucleus. Functional switching off of the cortex by means of loci toxic action reduces the amplitude of P-wave produced by stimulation of a point of the poisoned cortex. Spatial non-coincidence between the topography of foci of maximal activity of primary thalamo-cortical responses and the foci of maximal influences of the stimulated cortex on recurrent inhibition in VPL points to the likely involvement of the neocortical apparatus proper in recurrent thalamic inhibition.
D000818:Animals; D001931:Brain Mapping; D002415:Cats; D004558:Electric Stimulation; D005071:Evoked Potentials; D007031:Hypothalamus / Q000502:physiology*; D009433:Neural Inhibition; D009434:Neural Pathways; D012154:Reticular Formation / Q000502:physiology*; D013003:Somatosensory Cortex / Q000502:physiology*; D013787:Thalamic Nuclei / Q000502:physiology*
Uchastie neokortikal'nykh i retikulo-gipotalamicheskikh apparatov v reguliatsii vozvratnogo tormozheniia v talamicheskom peredatochnom iadre