The effects of acetazolamide on the human electroretinogram.
The effects of acetazolamied on the cerebral circulation and metabolism was previously shown to be due to a raised PCO2 in brain tissue. The effects of the drug on the human electroretinogram (ERG) are investigated in fifteen human volunteer subjects. A significant increase in the b-wave was found. A similitude with the mechanism of acetazolamide administration in brain and retinal tissue seems to be a possible explanation.
D000086:Acetazolamide / Q000494:pharmacology*; D000293:Adolescent; D000328:Adult; D002245:Carbon Dioxide / Q000378:metabolism; D002560:Cerebrovascular Circulation / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D004596:Electroretinography; D006801:Humans; D007223:Infant; D008875:Middle Aged; D012160:Retina / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism
D002245:Carbon Dioxide; D000086:Acetazolamide