title: Ultrastructural changes of the hypothalamo-hypophysial neurosecretory system in the magnesium deficient rats.
abstract: A magnesium deficient diet caused transient but marked degenerative changes in the rat hypothalamo-hypophysial neurosecretory system which strongly resembled in many ultrastructural respects those induced by a prolonged administration of aldosterone as previously reported by us. The possible mechanism for this selective alteration in the neurosecretory neurons has been briefly discussed with regard to aldosterone secretion.
mesh_terms: D000135:Acid Phosphatase / Q000032:analysis; D000450:Aldosterone / Q000378:metabolism; D000818:Animals; D001369:Axons / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D007030:Hypothalamo-Hypophyseal System / Q000648:ultrastructure*; D008275:Magnesium Deficiency / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D009410:Nerve Degeneration; D009474:Neurons / Q000648:ultrastructure; D010904:Pituitary Gland, Posterior / Q000648:ultrastructure; D010913:Pituitary-Adrenal System / Q000503:physiopathology; D051381:Rats; D013495:Supraoptic Nucleus / Q000648:ultrastructure; D013997:Time Factors
chemical_list: D000450:Aldosterone; D000135:Acid Phosphatase