title: [Geometric changes of the left ventricle during the isovolumic contraction in healthy people and patients with coronary disease].
abstract: Biplane cineventriculograms of 5 normal and 12 patients with coronary artery disease were analysed in order to determine the dimensional changes of the left ventricle during the isovolumic phase of contraction. In postero-arterior projection the ventricular diameters in both groups decreased by an average of 3-6%, the wall thickness increased by 5-10%, In lateral projection there were no significant changes of geometry. The changes in regional diameters showed significantly greater maximal differences in diseased than in normal ventricles. Using ventriculographic data of enddiastole instead of aortic valve opening for determination of ejection phase parameters resulted in an overestimation of the mean velocity of circumferential fiber shortening by an average of 10-20%, of the stroke volume of 5-15% and of the ejection fraction of 5%. These results indicate that ejection phase indices can only be determined exactly from cineventriculograms when aortic valve opening and closure is considered.
mesh_terms: D000328:Adult; D001021:Aortic Valve / Q000502:physiology / Q000503:physiopathology; D002302:Cardiac Output; D002932:Cineangiography; D003327:Coronary Disease / Q000503:physiopathology*; D006321:Heart / Q000033:anatomy & histology* / Q000502:physiology; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006801:Humans; D008875:Middle Aged; D009200:Myocardial Contraction
vernacular_title: Geometrische Anderungen des linken Ventrikels während der isovolumetrischen Kontraktion bei Gesunden und Koronarkranken