Differences in the immunogenicity of the HL-A antigens.
Comparing the expected and observed HL-A antibody forming in condition of fetomaternal immunization in 184 pregnant women, some differences in the immunogenic strength of HL-A antigens were investigated. The HL-A antigens were graded in three groups in accordance with their coefficient of immunogenicity as follows: in first group, with a coefficient more than 50 are HL-A2, HL-A7, HL-A5, W22, HL-A13, W27 and W10; in second group, with a coefficient from 25 to 50 are HL-A1, W24, HL-A11, W5, W14 and HL-A12; and in the third group, with a coefficient less than 25 are HL-A3, W25 and HL-A8. The data about the other HL-A antigens are not significant.
D000917:Antibody Formation; D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D005331:Fetomaternal Transfusion; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006650:Histocompatibility Testing; D006801:Humans; D007231:Infant, Newborn; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D011247:Pregnancy
D006680:HLA Antigens; D006649:Histocompatibility Antigens