[Renal osteopathy].
Bone histology and biochemical data indicate that hyperparathyroidism and abnormal metabolism of vitamin D are hallmarks of renal osteodystrophy. Early diagnosis is possible by means of bone biopsy. The clinical signs of renal bone disease include extraskeletal calcifications. Persistence of disease during hemodialysis treatment calls for treatment even of asymptomatic patients. Vitamin D3 and its metabolites or analogs play an important role in the suppression of hyperparathyreoidism and in combating osteomalacia.
D002118:Calcium / Q000627:therapeutic use; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000209:etiology*; D006801:Humans; D006961:Hyperparathyroidism / Q000188:drug therapy; D006962:Hyperparathyroidism, Secondary / Q000150:complications*; D010018:Osteomalacia / Q000188:drug therapy; D006435:Renal Dialysis / Q000009:adverse effects; D014511:Uremia / Q000628:therapy; D014807:Vitamin D / Q000378:metabolism* / Q000627:therapeutic use
D014807:Vitamin D; D002118:Calcium
Die renale Osteopathie