title: Blood gases in simple coal workers' pneumoconiosis.
abstract: Pulmonary gas exchange was measured at rest and during exercise in 30 normal males (14 smokers) and 43 coal workers free of obstructive syndrome, at three levels of oxygenation: hypoxia, normoxia and hyperoxia. The main results are the following: a) in normoxia PaO2 and (A--a)DO2 are slightly abnormal in coal workers at rest and during exercise; b) in hyperoxia (A--a)DO2 and venous admixture are higher in the miners at rest but not during exercise; c) in hypoxia (A--a)DO2 and DLO2 are abnormal in miners as compared with the control subjects; during exercise there is however no difference between the miners and the smokers of the control subjects; d) there is a correlation between PaO2 and (A--a)DO2 during exercise in normoxia and the various diffusion indices; e) (a--A)DCO2 and VD/VT show relatively slight increases in the miners; f) there are several differences between the miners with pin-head images and those with micronodular ones; g) at rest, (a--A)DCO2 and VD/VT are influenced by the degree of oxygenation. These various findings are discussed.
mesh_terms: D002245:Carbon Dioxide / Q000097:blood*; D003032:Coal Mining; D006801:Humans; D000860:Hypoxia / Q000097:blood; D008297:Male; D010100:Oxygen / Q000097:blood*; D010313:Partial Pressure; D005082:Physical Exertion; D011009:Pneumoconiosis / Q000097:blood*; D012126:Respiratory Dead Space; D012907:Smoking
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen