title: [Morphological characteristics of meningococcemia in children].
abstract: Observations were conducted over 8 children aged 5 months to 3 years and 2 months, in whom the disease developed acutely and was accompanied by collapse. Death occurred within the first 12--36 hours from the onset of the disease. Morphologically, there were revealed haemorrhagic rash, initial phenomena of serous-purulent meningitis, clear-cut disorders of the microcirculation (stasis, thrombosis) in the skin, lungs, myocardium, kidneys. The cause of early death of the children with meningoccaemia turned out to be the Waterhouse-Friderichsen syndrome, the morphological manifestations of the latter being bilateral haemorrhages into the adrenals. In the kidneys capillarothrombosis may develop, which is in accord with the picture of the Sanarelli-Schwartzmann phenomenon, and may lead to the development of acute renal insufficiency with formation of cortical necroses of the kidneys.
mesh_terms: D000311:Adrenal Glands / Q000473:pathology; D002675:Child, Preschool; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007223:Infant; D007668:Kidney / Q000473:pathology; D008168:Lung / Q000473:pathology; D008585:Meningitis, Meningococcal / Q000473:pathology; D008589:Meningococcal Infections / Q000150:complications / Q000473:pathology*; D008833:Microcirculation / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D018805:Sepsis / Q000150:complications / Q000473:pathology*; D012867:Skin / Q000473:pathology; D014884:Waterhouse-Friderichsen Syndrome / Q000209:etiology
vernacular_title: K morfologicheskoĭ kharakteristike meningokoktsemii u deteĭ