Incorporation of exogenous DNA and its localization in the chromosomes of the host cell.
Incorporation of isologous 3H-DNA of exogenous origin into chromosomes of the L cells was investigated by means of autoradiographical technique. It was shown that during short time intervals of incubation of 3H-DNA with the host cells (1--3 hr), nearly double quantity of the mitoses was labelled, when compared with 3H-TdR used as a control. During longer time intervals, no difference between number of the mitoses labelled with 3H-TdR and exogenous isologous 3H-DNA was observed.
D000818:Animals; D002463:Cell Membrane Permeability; D002875:Chromosomes / Q000378:metabolism*; D004247:DNA / Q000378:metabolism*; D005347:Fibroblasts / Q000378:metabolism; D007739:L Cells / Q000378:metabolism*; D051379:Mice; D008938:Mitosis
D004247:DNA