title: [The relative role of heredity and environment in genuine and symptomatic epilepsy].
abstract: The authors conducted a clinico-genetical study of 110 patients with symptomatic, 181 patients with genuine epilepsy and 236 normals of the general population. The study demonstrated the inadequacy of the alternative "inheritance--environment" in epilepsy. The frequency of epilepsy and disorders of an epileptic range in the relatives of patients with symptomatic epilepsy and partial seizures was less than in the relatives of patients with genuine epilepsy with generalized seizures. But they were significantly higher than in the general population. In symptomatic epilepsy in a rather large amount of cases (59.7%) there was a hereditary loading, while in patients with a definite hereditary loading in 36.4% of the cases of special significance were different exogenous factors. The results demonstrated the interaction of inheritance and environment and their influence on the age of appearance of fits and the degree of severity of epilepsy.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000150:complications / Q000209:etiology* / Q000235:genetics; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000150:complications
vernacular_title: Sootnositel'naia rol' nasledstvennosti i sredy pri genuinnoĭ i simptomaticheskoĭ épilepsii