Lysozyme in corneal ulcer.
In the present experimental study the role of lysozyme drops in healing of corneal ulcer of staphylococcal origin (sensitive to chloramphenicol) was studied on 16 albino rabbits. In 8 rabbits, in one eye placibo drops (distilled water) and in the other eye lysozyme 1% were put 4 times daily. In the other 8 rabbits, in one eye chloramphenicol drops 0.4% and in the other eye chloramphenicol drops 0.4% + lysozyme drops 1% were instilled 4 times daily. It was observed that the rate of healing of corneal ulcer was much earlier in the eyes which had local instillation of chloramphenicol drops + lysozyme in comparison to the eyes which had only chloramphenicol drops, lysozyme drops, or distilled water.
D000818:Animals; D002701:Chloramphenicol / Q000627:therapeutic use; D003320:Corneal Ulcer / Q000188:drug therapy*; D009113:Muramidase / Q000008:administration & dosage / Q000627:therapeutic use*; D009883:Ophthalmic Solutions; D011817:Rabbits; D012075:Remission, Spontaneous
D009883:Ophthalmic Solutions; D002701:Chloramphenicol; D009113:Muramidase