[The secretory function of the stomach in pre-tumorous conditions and tumors].
The effect of 3-methylcholanthrene, pretumor and tumor changes in the stomach on its secretory function was studied on 38 rats. Gastric secretion was not found to change due to the presence of the carcinogen in the stomach or due to developing pre-tumor changes in it. However, the developing tumor would produce considerable shifts in gastric secretion towards achylia. Such a reduction in the secretion results from a diminished functional area of the stomach and, presumably, from toxemia phenomena.
D000818:Animals; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000473:pathology; D008297:Male; D008748:Methylcholanthrene; D009374:Neoplasms, Experimental / Q000139:chemically induced; D011230:Precancerous Conditions / Q000139:chemically induced / Q000378:metabolism* / Q000473:pathology; D051381:Rats; D013274:Stomach Neoplasms / Q000139:chemically induced / Q000378:metabolism* / Q000473:pathology
D008748:Methylcholanthrene
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