title: [Effect of phentanyl on the hemodynamics].
abstract: The effect of Fentanyl upon the main haemodynamic parameters was studied in 10 patients free of any concomitant cardiac or pulmonary pathology. The drug was administered in a dosage of 0.001 mg/kg with a stable ventilational and circulatory level. A decrease of all indices of arterial pressure was observed (as a result of decreasing minute cardiac output and total peripheral resistance), as well as a slowing down of the cardiac rhythm, and reduction of the work of the heart. Fentanyl produces a multidirectional effect on the leading mechanisms of cardiac contractility.
mesh_terms: D001794:Blood Pressure / Q000187:drug effects; D002306:Cardiac Volume / Q000187:drug effects; D002496:Central Venous Pressure / Q000187:drug effects; D005283:Fentanyl / Q000494:pharmacology*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D009200:Myocardial Contraction / Q000187:drug effects; D014648:Varicose Veins / Q000601:surgery
chemical_list: D005283:Fentanyl
vernacular_title: Vliianie fentanila na gemodinamiku