title: The "inverted" pattern of the normal ventricular pressure curves: a syndrome with two possible angiocardiographic entities.
abstract: The "inverted" pattern of the normal ventricular pressure curves (VPCs) -- as herewith defined -- is considered a characteristic finding in patients with uncomplicated transposition of the great arteries (TGA). In more than 2,000 consecutive cases of congenital heart disease, this pattern was recorded in 6 patients. In all of them situs solitus was present with a large atrial septal defect (ASD) as the sole and obligatory defect. It is shown by angiocardiography in the "systemic" (venous) ventricle in all patients, that this ventricle is: I) the angiographic right ventricle in 5 patients, and II) the angiographic left ventricle in 1 patient. In I TGA with atrio-ventricular concordance (classic TGA) is diagnosed, while in II atrio-ventricular discordance with no TGA (isolated ventricular inversion) is diagnosed. In both instances a Mustard-type of operation is indicated. "Inverted" patterns of different magnitude are found. Therefore, as long as the pattern of VPCs is "inverted", differential diagnosis should be made during life between I classic TGA, and II isolated ventricular inversion.
mesh_terms: D000293:Adolescent; D000790:Angiocardiography; D006328:Cardiac Catheterization; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D014188:Transposition of Great Vessels / Q000175:diagnosis*