title: Hypoglycaemic effects of onion, Allium cepa Linn. on diabetes mellitus - a preliminary report.
abstract: Hypoglycaemic fractions of A. cepa Linn (onion) have been separated. After 7 days treatment, the more active hypoglycaemic fraction was about half as active as Phenformin in lowering the fasting blood sugar of alloxan-diabetic rabbits. Oral administration of the hypoglycaemic fraction to alloxan-diabetic rabbits improved their glucose tolerance also. Juice expressed residue of onion, when fed to diabetic patients along with their food, controlled the hyperglycaemia effectively.
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D003864:Depression, Chemical; D003920:Diabetes Mellitus / Q000097:blood*; D003921:Diabetes Mellitus, Experimental / Q000097:blood*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents; D008297:Male; D008875:Middle Aged; D010629:Phenformin / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology*; D011817:Rabbits
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D010629:Phenformin