A comparison of the in vitro activity of metronidazole, tinidazole, and nimorazole against Gram-negative anaerobic bacilli.
The in vitro activities of metronidazole, nimorazole, and tinidazole were compared against 69 strains of obligately anaerobic Gram-negative bacilli. Geometric mean MICs were 0-34, 1-05, and 0-28 mug/ml respectively. Thirty-six strains were also tested by the disk method. Correlation between MIC and diameter of the zones of inhibition was poor.
D006089:Gram-Negative Anaerobic Bacteria / Q000187:drug effects*; D008795:Metronidazole / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009554:Nimorazole / Q000494:pharmacology*; D009593:Nitroimidazoles / Q000494:pharmacology*; D014011:Tinidazole / Q000494:pharmacology*
D009593:Nitroimidazoles; D014011:Tinidazole; D008795:Metronidazole; D009554:Nimorazole