title: [Mechanism of inactivation and mutagenesis induced by ethyleneimine in Drosophila germ cells. V. Relation of complete and mosaic mutations during the supplementary action of high temperature].
abstract: Supplementary effect of high temperature (37 degrees C) an hour after the treatment of mature sperms of Drosophila with ethylene imine resulted in an increased level of the inactivation (the frequency of dominant lethal mutation). The frequency of complete mutations (recessive sex-linked lethal mutations) increased by the supplementary effect of high temperature at low doses of E1, and it did not change under a comparatively high dose of the mutagen. The frequency of mosaic mutations decreased under the effect of high temperature at both doses of E1. No effect of high temperature was observed in 4 and 24 h after the E1 treatment. The results obtained are discussed in connection with the proportion of inactivation and mutagenesis under the effect of chemical mutagens on Drosophila germ cells.
mesh_terms: D000818:Animals; D001388:Aziridines; D005799:Genes, Dominant; D005804:Genes, Lethal; D005808:Genes, Recessive; D006358:Hot Temperature; D008297:Male; D009030:Mosaicism; D009153:Mutagens; D009154:Mutation; D012730:Sex Chromosomes / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects*
chemical_list: D001388:Aziridines; D009153:Mutagens
vernacular_title: Izuchenie mekhanizma inaktivatsii i mutageneza pri deĭstvii étilenimina na polovye kletki drozofily. Soobshchenie V. Sootnoshenie polynkh i mozaichnykh mutatsiĭ pri dopolnitel'nom deĭstvii vysokoĭ temperatury