title: [The effect of radiation therapy on the course of the tumor process in patients with laryngeal cancer].
abstract: The authors have studied the effect of radiotherapy on immune responsiveness in 36 patients with laryngeal cancer. The kinetics of variations in the skin cover bacterial picture, as well as some indices of nonspecific (anti-infective) humoral immunity (the titre of agglutinines, general bactericidity of blood sera against the proper staphylococci of the skin and the content of staphylococcic antitoxin) were followed up depending on dosage of irradiation. It was found that radiation therapy with the total focal dosage of 2000 rad in 72% of cases contributed to activation of protective forces of the organism; in larger doses (2001-8000 rad) of irradiation the indices of nonspecific immunity in every patient were found to be reduced.
mesh_terms: D000328:Adult; D000368:Aged; D000992:Antitoxins / Q000032:analysis; D001770:Blood Bactericidal Activity; D005260:Female; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis / Q000209:etiology*; D007822:Laryngeal Neoplasms / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D011867:Radioisotope Teletherapy / Q000009:adverse effects; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D012867:Skin / Q000382:microbiology
chemical_list: D000992:Antitoxins
vernacular_title: Vliianie luchevoi terapii na techenie opukholevoĭ protsessa u bol'nykh rakom gortani