Production of prostaglandin-like substance at the time of mating in the rat.
The amount of prostaglandin-like substance (PG--LS) in the reproductive tract of the male and female rat following mating (p.c.) has been measured and compared with non-mated (control) values. Negligable amounts of PG-LS were detected in the control female tracts but a mean of 2 mug PGE, equivalents was detected immediately p.c. The PG--LS is probably generated in the vas deferens since nearly 1 mug PGE1 equivalents per rat remained there p.c. No other tissue in the male reproductive tract contained significant amounts of PG--LS suggests that the bulk of the activity is due to PGE2 with a smaller amount being due to PGF2 alpha.
D000818:Animals; D002584:Cervix Uteri / Q000378:metabolism; D003307:Copulation; D005187:Fallopian Tubes / Q000378:metabolism; D005260:Female; D005836:Genitalia, Female / Q000378:metabolism*; D005837:Genitalia, Male / Q000378:metabolism*; D008297:Male; D011453:Prostaglandins / Q000096:biosynthesis*; D011467:Prostate / Q000378:metabolism; D051381:Rats / Q000378:metabolism*; D012669:Seminal Vesicles / Q000378:metabolism; D013737:Testis / Q000378:metabolism; D014599:Uterus / Q000378:metabolism; D014621:Vagina / Q000378:metabolism; D014649:Vas Deferens / Q000378:metabolism
D011453:Prostaglandins