ADP-induced platelet aggregation in vivo after exclusion of different circulatory districts.
The effect of the ADP infusion on the basal platelet count was studied in controls and in rats submitted to the exclusion of the following circulatory districts: splenic, renal, cerebral and of a hind-limb. After these exclusions the ADP-induced thrombocytopenia was less marked than the controls.
D000244:Adenosine Diphosphate / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D001792:Blood Platelets / Q000187:drug effects*; D002339:Carotid Arteries; D005263:Femoral Artery; D007263:Infusions, Parenteral; D008026:Ligation; D010974:Platelet Aggregation; D051381:Rats; D012077:Renal Artery; D013157:Splenic Artery; D013921:Thrombocytopenia / Q000139:chemically induced*
D000244:Adenosine Diphosphate