The Bernard-Soulier syndrome: hereditary giant platelet disease.
A patient with the Bernard-Soulier or hereditary giant platelet syndrome, in whom the characteristic morphological features were present and the in vitro abnormalities of platelet aggregation were demonstrated, is reported. Although rare, this syndrome is important, since surgical procedures may be carried out under cover of infused allogeneic platelets.
D000328:Adult; D001791:Blood Platelet Disorders / Q000235:genetics* / Q000503:physiopathology; D006801:Humans; D008297:Male; D010974:Platelet Aggregation; D013577:Syndrome