title: [Complications from antibiotic therapy].
abstract: Analysis of 302 side effects of antibiotic theraphy is presented. The side effects were studied comparatively as dependent on the antibiotic group. Dependence of the toxic and toxicoallergic reactions to the antibiotics on the antibiotic blood levels were noted. Previous sensitization resulted in more frequent and earlier side effects. The analysis and clinical observations showed that antibiotic therapy should take into account the results of the laboratory tests, i.e. examination of the kidney functional state, antibiotic levels in the blood and urine, tolerance of the drug by the patient.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000617:Aminoglycosides / Q000009:adverse effects; D000707:Anaphylaxis / Q000473:pathology; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D004342:Drug Hypersensitivity / Q000209:etiology / Q000276:immunology / Q000473:pathology; D004917:Erythromycin / Q000009:adverse effects; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000473:pathology; D007668:Kidney / Q000187:drug effects; D007962:Leukocytes / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000139:chemically induced; D009827:Oleandomycin / Q000009:adverse effects; D010406:Penicillins / Q000009:adverse effects; D012867:Skin / Q000187:drug effects; D013307:Streptomycin / Q000009:adverse effects; D013752:Tetracycline / Q000009:adverse effects; D014551:Urinary Tract / Q000187:drug effects
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D010406:Penicillins; D004917:Erythromycin; D013752:Tetracycline; D009827:Oleandomycin; D013307:Streptomycin
vernacular_title: Oslozhneniia ot antibiotikoterapii