[Hormonal treatment of breast cancer from surgical point of view (author's transl)].
At present the best results in treating breast cancer of stage I and II appear to be achieved by surgery alone. As an alternative method preference should be given to the so-called classical radical mastectomy. Restriction or widening of operative management may be useful in some cases, but the indication is problematic. There is a high risk of applying appropriate procedures to inappropriate patients. In radical mastectomy the incidence of errors and complications comes within reasonable limits. On the contrary, in stage III additional treatment is well justified. At this stage, surgery alone gives poor results. The fate of stage III patients first of all depends on the presence or absence of metastases; therefore, preference should be given to systemic additional treatment, but on the basis of individualized tried measures. Polypragmasia and blind systemic treatment are to be avoided. The time schedule of such additional treatment are to be avoided. The time schedule of such additional treatment has to be established, by controlled clinical trials. From these considerations, the following requirements can be formulated: 1. improvement of the oncologic level 2. centralisation in oncologic treatment and diagnostics 3. enlargement of existing or creation of new facilities for bi-chemical and other testing, and for scientific investigation at the oneologic centers.
D001943:Breast Neoplasms / Q000628:therapy*; D004358:Drug Therapy; D004992:Ethics, Medical; D005260:Female; D006728:Hormones / Q000627:therapeutic use; D006801:Humans; D008408:Mastectomy
D006728:Hormones
Hormonelle Behandlung des Mammakarzinoms aus chirurgischer Sicht