[The morphology of the microcirculatory system of the visceral pleura in chronic non-specific lung diseases].
In chronic nonspecific diseases of the lungs lesions of the microcirculatory system of the visceral pleura are of generalized character. The most marked changes were observed in postcapillary and venular links of the microhemocirculation. A pronounced hypertrophy of the venular department and rearrangement of the postcapillary network were noted. The microcirculatory lymphatic system was found to be considerably developed. Along with the functioning lymphatic network there were seen emptying sclerosing lymphatic vessels. The changes in vascular terminals revealed were directly dependent upon the duration of the disease, character of expansion of the process in the lungs, degree of cardiopulmonary incompetence. Moreover, disorders of rheological properties of the blood and permeability of vessels were observed, these disorders being particularly pronounced in exacerbation of chronic pneumonia and cor pulmonale insufficiency of II-III degree. It may be assumed that changes in the microcirculation system in chronic nonspecific lung diseases may represent both an important link in the compensatory mechanisms at early stages of the disease and also a cause of deep irreversible metabolic disturbances in persisting and progressing process in the lungs.
D000328:Adult; D002199:Capillary Permeability; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000473:pathology*; D010994:Pleura / Q000098:blood supply* / Q000473:pathology; D011014:Pneumonia / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D011660:Pulmonary Heart Disease / Q000150:complications
Morfologiia mikrotsirkuliatornoĭ sistemy vistseral'noĭ plevry pri khronicheskikh nespetsificheskikh zabolevaniiakh legkikh