Effect of piperazine on the level of phospholipids and on the activities of certain enzymes of phospholipid metabolism in human Ascaris lumbricoides.
The phospholipid level in the human parasitic nematode Ascaris lumbricoides is decreased by piperazine, by partially stimulating catabolic enzymes such as phospholipase C and partially inhibiting anabolic enzymes such as choline kinase.
D000818:Animals; D001200:Ascaris / Q000187:drug effects* / Q000378:metabolism; D002797:Choline Kinase / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D010713:Phosphatidylcholines / Q000378:metabolism; D010714:Phosphatidylethanolamines / Q000378:metabolism; D010740:Phospholipases / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D010879:Piperazines / Q000494:pharmacology*
D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010743:Phospholipids; D010879:Piperazines; D002797:Choline Kinase; D010740:Phospholipases