title: Effect of ethanol on phospholipid metabolism by the rat lung.
abstract: Prefeeding of alcohol shows the in vivo incorporation of orally administered palmitic acid into phosphatidylcholine of the lung. This impairment is also demonstrable in vitro utilizing lung slices and 14C-labeled palmitate or cytidine 5'-diphosphocholine as precursors. It is concluded that alcohol ingestion affects the utilization of precursors needed for phospholipid formation in the lung.
mesh_terms: D000818:Animals; D003566:Cytidine Diphosphate Choline / Q000378:metabolism; D003864:Depression, Chemical; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D066298:In Vitro Techniques; D007408:Intestinal Absorption; D008168:Lung / Q000187:drug effects / Q000378:metabolism*; D010169:Palmitic Acids / Q000378:metabolism; D010713:Phosphatidylcholines / Q000096:biosynthesis; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats
chemical_list: D010169:Palmitic Acids; D010713:Phosphatidylcholines; D010743:Phospholipids; D000431:Ethanol; D003566:Cytidine Diphosphate Choline