[Influence of polychlorpinene on the cholate forming and conjugating functions of the liver].
Tests conducted with 69 rabbits ascertained a marked influence of acute and chronic poisoning with polychlorpinene on the synthesis and conjugation of bile acids with glycine and taurine. In cases of acute poisoning there was observed an inhibition of the bile acids synthesis, while in chronic poisoning there occurred an insignificant activation of the latter. In acute poisoning the conjugating function of the liver is grossly upset in regard to taurine and glycine and in chronic poisoning-to glycine.
D000818:Animals; D001647:Bile Acids and Salts / Q000096:biosynthesis*; D005998:Glycine / Q000378:metabolism; D007306:Insecticides / Q000009:adverse effects*; D008099:Liver / Q000187:drug effects*; D008297:Male; D011817:Rabbits; D013654:Taurine / Q000378:metabolism; D013729:Terpenes / Q000009:adverse effects*
D001647:Bile Acids and Salts; D007306:Insecticides; D013729:Terpenes; D013654:Taurine; D005998:Glycine
Vliianie polikhlorpinena na kholatoobrazuiushchuiu i kon'iugiruiushchuiu funktsii pecheni