[A transplantable myeloid hamster leukemia with high peripheral leukocyte counts and C-particles. I. Transplantation experiments, pathogenesis, and electron-microscopic observations (author's transl)].
In this article is reported a generalized leukemia of the myeloproliferative system of golden hamsters capable of cellular transmission. Cellfree transmissions to 83 golden hamsters after a 6-month latency period, have so far yielded the same result in three cases. After cellular transplantation leukocyte counts of 180,000 on the average occured abruptly in the end-phase of the disease. Latencies were between 4 and 10 days. Electronmicroscopically, oncorna-viruses were demonstrated in hamsters inoculated with either the cellular or the cellfree preparation that bear close resemblance to the murine C-particles.
D000818:Animals; D006224:Cricetinae; D007942:Leukemia, Experimental / Q000097:blood / Q000473:pathology*; D007958:Leukocyte Count; D008099:Liver / Q000473:pathology; D008854:Microscopy, Electron; D009368:Neoplasm Transplantation; D009858:Oncogenic Viruses / Q000302:isolation & purification; D013154:Spleen / Q000473:pathology; D014184:Transplantation, Homologous
Uber eine transplantable myeloische Hamsterleukämie mit hohen peripheren Blutwerten und C-Partikelbefund. I. Mitt.: Transplantationsversuche, Pathogenese, elektronenmikroskopische Befunde