Absorption of sulfate ions in the rat lung.
To investigate the absorption of 35S-sulfate ions from the rat lung in the presence of sodium, ammonium, and chloride ions, 0.1 ml of isotonic sucrose solution containing the salts was instilled via a tracheal cannula into anesthetized animals. After various times the lungs were removed and assayed for 35S-radioactivity. Sulfate ion absorption was found to be nonsaturable and proportional to the concentration of sulfate ion, with a t 1/2 =34.5 minutes. Ammonium ions enhanced the absorption of sulfate ions by 10.8 +/- 3.1% and chloride ions decreased the absorption of sulfate ions by 6.6 +/- 3.0%.
D000042:Absorption; D000818:Animals; D002712:Chlorides / Q000494:pharmacology; D006207:Half-Life; D007442:Intubation, Intratracheal; D007552:Isotonic Solutions; D008168:Lung / Q000187:drug effects / Q000378:metabolism*; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology; D051381:Rats; D012964:Sodium / Q000494:pharmacology; D013395:Sucrose / Q000494:pharmacology; D013431:Sulfates / Q000008:administration & dosage / Q000378:metabolism*; D013462:Sulfur Radioisotopes
D002712:Chlorides; D007552:Isotonic Solutions; D000644:Quaternary Ammonium Compounds; D013431:Sulfates; D013462:Sulfur Radioisotopes; D013395:Sucrose; D012964:Sodium