title: [Importance of moulds in the morphogenesis of pulmonary changes in chronic infantile granulomatosis].
abstract: A brief clinical and a rather detailed histological decription is given of three male siblings suffering from chronic granulomatosis. Two types of granulomas were indentified. One of them occurring extrapulmonally resembled the specific tuberculous granuloma with caseation, but tuberculous bacilli not demonstrated. The other type of granuloma was found in the lungs and was composed of a leucocytic core surrounded by an epithelioid cellular rim containing giant cells. In all the three cases such granulomas were shown to contain mould filaments of the aspergillus type.
mesh_terms: D000328:Adult; D001228:Aspergillosis / Q000150:complications; D002648:Child; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D006801:Humans; D007223:Infant; D008172:Lung Diseases, Fungal / Q000150:complications*; D008297:Male; D010585:Phagocyte Bactericidal Dysfunction / Q000209:etiology*; D012737:Sex Factors
vernacular_title: Význam plísní v morfogeneze plicních zmĕn pri chronické granulomatóze dĕtského vĕku