Oxygen and carbon dioxide tensions in healing tissue.
Oxygen and carbon dioxide tensions were studied in experimental granulation tissue growing into a thin sheet of cellulose sponge. Both the base-line PO2 and the response in oxygen tension to pure O2-breathing were highest in 7-day-old implants, displaying a slight decrease as the healing progressed. Lower tissue carbon dioxide tensions and oxygen consumption rates were noticed also in older implants. The oxygen tension gradient between the wound fluid and the edge of the granulation tissue in cylindrical cellulose sponge implants decreased as the healing progressed.
D000818:Animals; D002245:Carbon Dioxide / Q000378:metabolism*; D006097:Granulation Tissue / Q000378:metabolism*; D007424:Intracellular Fluid / Q000378:metabolism; D008297:Male; D008839:Microelectrodes; D010101:Oxygen Consumption; D051381:Rats; D014945:Wound Healing
D002245:Carbon Dioxide