[Disseminated intravascular coagulation and acute renal failure in an infant. Treated with streptokinase and peritoneal dialysis (author's transl)].
An infant, aged seven months, developed toxic shock with acute renal failure as a sequel to the development of hypertonic dehydration. The anuric phase persisted despite treatment of the dehydration and diuretic infusions. The coagulation tests showed signs of disseminated intravascular coagulation and so the child was given fibrinolytic therapy for 36 hours following initial heparinization. Excretion of urine recommenced 8 hours after the initiation of fibrinolytic therapy. Peritoneal dialysis was carried out in parallel with the fibrinolytic treatment without haemorrhagic complications. It was possible to terminate dialysis on the fourth day already and renal function subsequently recovered completely.
D058186:Acute Kidney Injury / Q000209:etiology / Q000628:therapy*; D003681:Dehydration / Q000150:complications / Q000628:therapy*; D004211:Disseminated Intravascular Coagulation / Q000188:drug therapy / Q000628:therapy*; D004232:Diuretics / Q000627:therapeutic use; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007263:Infusions, Parenteral; D008297:Male; D010530:Peritoneal Dialysis; D012772:Shock, Septic / Q000209:etiology; D013300:Streptokinase / Q000008:administration & dosage / Q000627:therapeutic use*
D004232:Diuretics; D005343:Fibrinolytic Agents; D013300:Streptokinase
Disseminierte intravasale Gerinnung und akutes Nierenversagen bei einem Sāugling