[Placental changes in diabetes mellitus with special reference to villi maturation disorders. (Morphological findings and severity of the disease)].
The placentas of 30 cases of diabetes mellitus were examined. The degree of severity of the disease was classified according to the schema of White. Related to the gestation period different degrees of severity of diabetes mellitus revealed nearly the same weight of the placentas. Similar relations were found referred to the height of the placenta-child-index. Implantation lesions occured in 56, 7% of all cases, most of these in cases with strong diabetes mellitus. The greater number of lesions were insertion anomalies of the cord. All placentas-showed disturbed circulation by dominance of disturbed blood supply. A relation to the degree of the severity of the disease wasn't provable. Very often we found villi necrosis and proliferations of the syncytiotrophoblast. Also we could see alterations of the villi vessels and a compensatory angiomatosis. 83,3% of diabetes cases showed disturbed maturation of the villi; the grade of these changes could not be referred to the degree of severity of this disease; it was merely a ramification block. The authors point out that in diabetes mellitus the degree of danger to the pregnancy does not depend on the severity of the maternal disease. It is always necessary to have a sufficient metabolic condition.
D000798:Angiomatosis / Q000150:complications; D002824:Chorionic Villi / Q000098:blood supply; D005260:Female; D006801:Humans; D009336:Necrosis; D009929:Organ Size; D010920:Placenta; D010922:Placenta Diseases / Q000175:diagnosis* / Q000209:etiology; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000150:complications* / Q000175:diagnosis
Plazentaveränderungen bei Diabetes mellitus unter besonderer Berücksichtigung von Zottenreifungsstörungen. (Morphologischer Befund und Schweregrad der Erkrankung)