Hexokinase isozymes in human neoplastic and fetal tissues: the existence of hexokinase II in malignant tumors and in placenta.
The distribution of electrophoretic fractions of hexokinase (HK E.C. 2.7.1.1) in extracts of 53 human primary tumors, homologous normal tissues and fetal organs was investigated. It was found that the fraction HK II is present in every malignant tumor and in placenta tissue.
D005260:Female; D005333:Fetus / Q000201:enzymology; D006593:Hexokinase / Q000378:metabolism*; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D009369:Neoplasms / Q000201:enzymology*; D010920:Placenta / Q000201:enzymology*; D011247:Pregnancy; D011770:Pyruvate Kinase / Q000378:metabolism
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D006593:Hexokinase; D011770:Pyruvate Kinase