title: [Regan-isoenzyme of alkaline phosphatase in sera of cancer patients (author's transl)].
abstract: The Regan-Isoenzyme of alkaline phosphatase was determined immunologically measuring the antibody-fixed tumor alkaline phosphatase activity. In 68 blood donors the normal range varied from 0.1145 to 0.6351 (delta E/20 min at 405 nm, chi = 0.3748, standard deviation = 0.1013). 28.9% of 83 patients with different carcinomas showed a pathologically elevated Regan-Isoenzyme activity in the serum. The percentage of positive results as compared to previous reports is higher due to a more sensitive technique.
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood*; D001842:Bone and Bones / Q000201:enzymology; D002272:Carcinoembryonic Antigen / Q000032:analysis; D003429:Cross Reactions; D005260:Female; D006801:Humans; D007106:Immune Sera; D007421:Intestine, Small / Q000201:enzymology; D007527:Isoenzymes / Q000097:blood*; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D009369:Neoplasms / Q000201:enzymology*; D010920:Placenta / Q000201:enzymology; D011247:Pregnancy
chemical_list: D002272:Carcinoembryonic Antigen; D007106:Immune Sera; D007527:Isoenzymes; D000469:Alkaline Phosphatase
vernacular_title: Regan-isoenzym der alkalischen Phosphatase im Serum bei malignen Tumoren