Intracerebral prostaglandin E2: effects upon sexual behavior, open field activity and body temperature in ovariectomized female rats.
A single 27 gauge implant of PGE2 into the periventricular region of the hypothalamus resulted in a significant increase in sexual receptivity in estrogen primed, ovariectomized female rats. Open field activity levels were only slightly decreased while rectal body temperature increased significantly over control values. It is postulated that the effects upon sexual receptivity might be mediated by PGE2 stimulated LRF release.
D000818:Animals; D001831:Body Temperature / Q000187:drug effects*; D002369:Castration; D005106:Exploratory Behavior / Q000187:drug effects*; D005260:Female; D007276:Injections, Intraventricular; D011187:Posture; D011458:Prostaglandins E / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D013268:Stimulation, Chemical
D011458:Prostaglandins E