Increased disrupting effects of haloperidol on a conditioned avoidance response after 6-hydroxydopamine treatment.
The influence of prior catecholamine depletion was studied on the behavioral depressant effects of haloperidol using a conditioned avoidance response. The butyrophenone disrupting effects on the avoidance behavior were significantly increased by 6-hydroxydopamine pretreatment.
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D001921:Brain / Q000378:metabolism; D002395:Catecholamines / Q000378:metabolism; D003864:Depression, Chemical; D004357:Drug Synergism; D006220:Haloperidol / Q000494:pharmacology*; D006892:Hydroxydopamines / Q000494:pharmacology*; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D051381:Rats
D002395:Catecholamines; D006892:Hydroxydopamines; D006220:Haloperidol