Prostaglandin-induced choleresis in the rat.
It could be demonstrated that intraportal infusion of prostaglandin A1 (1 mug/min/100 g body wt.) in Wistar rats significantly increases bile flow. An analysis of the relationship between bile salt excretion and bile flow revealed that this choleresis is due to an increase in the bile salt independent fraction of bile.
D000818:Animals; D001646:Bile / Q000032:analysis / Q000378:metabolism*; D001647:Bile Acids and Salts / Q000032:analysis; D001794:Blood Pressure / Q000187:drug effects; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D011169:Portal Vein; D011454:Prostaglandins A / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D013656:Taurocholic Acid / Q000378:metabolism
D001647:Bile Acids and Salts; D011454:Prostaglandins A; D013656:Taurocholic Acid