Evidence for purine biosynthesis in human leukocytes.
Human leukocytes and lymphocytes have shown to be equipped with 5-phosphoribosyl-1-pyrophosphate amidotransrease, the enzyme which catalyzes the synthesis of the first intermediate of the purine pathway, thus providing evidence that these cells have the capacity for de novo purine biosynthesis.
D000582:Amidophosphoribosyltransferase / Q000097:blood*; D006801:Humans; D007962:Leukocytes / Q000201:enzymology*; D008214:Lymphocytes / Q000201:enzymology; D010430:Pentosyltransferases / Q000097:blood*; D011687:Purines / Q000096:biosynthesis*
D011687:Purines; D010430:Pentosyltransferases; D000582:Amidophosphoribosyltransferase