title: [The function of the diseased kidney].
abstract: A few years ago the kidney in chronic renal failure was described as a mass of tissue "without significance, vanishing into the disparity of thousands of fantastically altered organs of strange design and anomalous behaviour". In order to refute this opinion, some of the morphological and pathophysiological evidence is summarized which points to the fact that even in chronic renal failure the remaining nephrons that contribute to renal function behave as a rather homogeneous population characterized by appropriate adaptations of glomerular and tubular functions and by a persistent responsiveness to the changing needs of the patient.
mesh_terms: D000136:Acid-Base Equilibrium; D001692:Biological Transport; D005947:Glucose; D006801:Humans; D007668:Kidney / Q000502:physiology* / Q000503:physiopathology; D007671:Kidney Concentrating Ability; D007676:Kidney Failure, Chronic / Q000503:physiopathology*; D009399:Nephrons / Q000502:physiology*; D010710:Phosphates / Q000652:urine; D011188:Potassium / Q000652:urine; D012964:Sodium / Q000652:urine
chemical_list: D010710:Phosphates; D012964:Sodium; D005947:Glucose; D011188:Potassium
vernacular_title: Die Funktion der insuffizienten Niere