[Effect of x-rays on the hemolytic substances of the Yoshida ascites tumor].
Ricinoleic-like haemolytic substances were isolated from tumour cells and peritoneal liquid fractions in rats with Yoshida's ascities hepatoma. Their activity was measured by means of photometric techniques. Crossed haemolytic tests showed differences in the choice expressed by these substances for the red cells of animals of various species. Whole body irradiation led to changes in the quantity of these substances. Their metabolism was examined by administering 3H2- and 14C6-labelled oleic acid. A variety of results was observed. Microscopic examination of target red cells in a study of the oleic acid-lysine-membrane bond confirmed the results given by the densitometer.
D000818:Animals; D001202:Ascitic Fluid / Q000032:analysis; D006460:Hemolysin Proteins / Q000528:radiation effects*; D008113:Liver Neoplasms / Q000032:analysis / Q000378:metabolism; D008239:Lysine / Q000378:metabolism; D009374:Neoplasms, Experimental / Q000032:analysis / Q000378:metabolism; D011830:Radiation Effects; D051381:Rats; D012277:Ricinoleic Acids / Q000378:metabolism
D006460:Hemolysin Proteins; D012277:Ricinoleic Acids; D008239:Lysine
Effetto dei raggi X sulle sostanze emolitiche del tumore ascite di Yoshida