[Possibility of internal organization of RNA and proteins in ribosomal subparticles. A structural model of Escherichia coli 30S ribosomal subparticle].
The hypothetic model of reciprocal spatial arrangement of 18 from 21 proteins in the E. coli 30S ribosomal subparticle is suggested. The model is based on conception of the 16S R-A molecule macrostrand which is the right superhelix in the subparticle composition. Macrohelix's biopolarity against single-stranded sites of RNA and its small width result in that proteins binding with single-stranded RNA organized in chain, one-number sequence. The double helixes uniting the corresponding one single-stranded sites of RNA play the role of rigid transmission between them. So, in the course of subparticles reconstruction from RNA and proteins the spatially uncoupled proteins can interact without its direct contact. The model takes into consideration the vast amount of information.
D001665:Binding Sites; D004926:Escherichia coli / Q000032:analysis / Q000648:ultrastructure*; D046911:Macromolecular Substances; D008954:Models, Biological; D008961:Models, Structural; D009690:Nucleic Acid Conformation; D011485:Protein Binding; D011487:Protein Conformation; D012335:RNA, Ribosomal; D012269:Ribosomal Proteins; D012270:Ribosomes / Q000032:analysis / Q000648:ultrastructure*
D046911:Macromolecular Substances; D012335:RNA, Ribosomal; D012269:Ribosomal Proteins
O vozmozhnoĭ vnutrenneĭ organizatsii RNK i belka v subchastitsakh ribosom. Model' postroeniia 30S subchastisty ribosom E. coli