title: Effect of carbon-tetrachloride and mercuric chloride on the tocopherol and ubiquinone content of liver and kidney.
abstract: Authors examined changes in the total ubiquinone and tocopherol contents of livers and kidneys obtained from rats acutely poisoned by carbon-tetrachloride and mercuric-chloride. Following administration of carbon-tetrachloride after 48 h the liver ubiquinone content per 100 g tissue decreased from 11.80 +/- 2.44 mg to 7.24 +/- 2.15 mg, while the kidney ubiquinone content changed from 14.16 +/- 3.96 mg to 5.98 +/- 2.93 mg. The total tocopherol content remained unaltered. Fourty-eight hours after administration of mercuric-chloride, the liver total tocopherol and total ubiquinone contents showed no changes, the tocopherol content of the kidney dropped from 6.16 +/- 2.10 mg to 3.16 +/- 1.48 mg, while the total ubiquinone content remained unaltered.
mesh_terms: D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008630:Mercury Poisoning / Q000378:metabolism*; D051381:Rats; D014810:Vitamin E / Q000378:metabolism*
chemical_list: D014810:Vitamin E