Toxic maculopathy part II: A result of quinine usage as demonstrated by fluorescein angiography and electroretinography.
In this paper, further investigation by fluorescein angiography and electroretinography (ERG) was undertaken to substantiate the possible toxic maculopathy due to quinine usage. Again, positive Amsler chart tests were found in 3 of 14 (21%) of the drug addicts with blurred vision, a common complaint among these patients. The results of 5 fluorescein angiography examinations demonstrated no leakage of dye, especially in the macula. Twenty-four ERG examinations revealed no statistical differences between the test group patients and the control subjects. It was concluded that there is a definite need to carefully examine the eyes of any person who has used quinine for a long time since positive Amsler chart tests were found in 37% of the drug addicts.
D004596:Electroretinography; D005451:Fluorescein Angiography; D006556:Heroin Dependence / Q000503:physiopathology; D006801:Humans; D008266:Macula Lutea / Q000503:physiopathology*; D010786:Photoreceptor Cells / Q000503:physiopathology; D011803:Quinine; D012171:Retinal Vessels / Q000503:physiopathology; D019966:Substance-Related Disorders / Q000503:physiopathology*
D011803:Quinine