Stabilization of brain free polysomes by morphine.
The effect of morphine on brain free polysomes prepared from mouse brain was studied. It was found that morphine binds to polysomes and protects them from disaggregation. The significance of this effect with respect to brain protein is discussed.
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000648:ultrastructure*; D002499:Centrifugation, Density Gradient; D066298:In Vitro Techniques; D051379:Mice; D009020:Morphine / Q000494:pharmacology*; D009419:Nerve Tissue Proteins / Q000378:metabolism; D011132:Polyribosomes / Q000187:drug effects* / Q000378:metabolism; D013997:Time Factors
D009419:Nerve Tissue Proteins; D009020:Morphine