title: [Venereal granuloma (donovaniasis) in France].
abstract: The study of six cases of MacLeod-Donovan chancre, 2 in Paris, 4 in Brest, in young men coming from the West Indies, showed after 15 days incubation, a balano-preputial lesion consisting of an oval-shaped granuloma, 1 to 4 cm diameter, raised, indurated, ulcerated, reddish-yellow, spontaneously painful, bleeding easily, accompanied in 50 p. 100 of cases by inguinal adenitis, due to secondary infection. Swabs, which should be repeated, showed Donovan bodies within numerous histiocytes. The inactivity of penicillin may be contrasted with the rapidly favourable effect of streptomycin, chloramphenicol or aureomycin.
mesh_terms: D000328:Adult; D002701:Chloramphenicol / Q000627:therapeutic use; D002751:Chlortetracycline / Q000627:therapeutic use; D005602:France; D006100:Granuloma Inguinale / Q000188:drug therapy; D006801:Humans; D008297:Male; D010406:Penicillins / Q000627:therapeutic use; D013307:Streptomycin / Q000627:therapeutic use; D014900:West Indies / Q000208:ethnology
chemical_list: D010406:Penicillins; D002701:Chloramphenicol; D002751:Chlortetracycline; D013307:Streptomycin
vernacular_title: Le granulome vénérien (donovanose) en France