[Effect of Triton-100 on activity and solubilization of brain acid proteinases].
The activity and solubilization of acid proteinases of grey and white matter of the cat great cerebral hemispheres were studied as affected by the detergent triton X-100. High concentrations of the detergent evoke a significant decrease of the activity in grey matter and significant increase--in white one. It is found that 20-25% of the activity of the grey matter acid proteinases are strongly bound with the studied tissues and not release under the effect of the detergent in high concentrations.
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology*; D002415:Cats; D010447:Peptide Hydrolases / Q000302:isolation & purification / Q000378:metabolism*; D011092:Polyethylene Glycols / Q000494:pharmacology*; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D012995:Solubility
D000644:Quaternary Ammonium Compounds; D011092:Polyethylene Glycols; D010447:Peptide Hydrolases
Vplyv Trytonu Kh-100 na aktyvnist' ta soliubilizatsiiu kyslykh proteinaz mozku