Synthesis of dl-4xi-(2-carboxyethyl)-cis-hexahydropyrrolo-[3,4-d]imidazol-2-one (bisnorazabiotin).
Bisnorazabiotin was synthesized in a six-step sequence from 1,5-dioxo-2-carbethoxypyrrolizidine. It is anticipated that the molecule will serve as a cofactor for biotin-requiring enzymes.
D001372:Aza Compounds / Q000138:chemical synthesis; D001710:Biotin / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D007093:Imidazoles / Q000138:chemical synthesis*; D008722:Methods
D001372:Aza Compounds; D007093:Imidazoles; C011409:bisnorazabiotin; D001710:Biotin