Effect of pyrazole administration on the isopropanol induced fatty liver.
The isopropanol induced fatty liver is prevented in the rat by prior administration of pyrazole. Acetone administration, on the other hand, determines an increase in the hepatic triglyceride level. These results suggest the implications of acetone in the induction of the fatty liver following acute isopropanol administration in the rat.
D000433:1-Propanol / Q000494:pharmacology; D000096:Acetone / Q000494:pharmacology; D000818:Animals; D005234:Fatty Liver / Q000139:chemically induced / Q000517:prevention & control*; D008099:Liver / Q000032:analysis; D011720:Pyrazoles / Q000627:therapeutic use*; D051381:Rats; D014280:Triglycerides / Q000032:analysis
D011720:Pyrazoles; D014280:Triglycerides; D000096:Acetone; D000433:1-Propanol