[Penetration of anti-lysosome serum in macrophages and the localization of anti-lysosome antibodies in their structures].
Penetration of antilysosomal sera into living macrophages, their localization on subcellular structures, and their effects upon the cell, were studied by means of immunofluorescence technique. The rabbit antilysosomal (antimembrane) immune globulins were found to be ingested by the mouse macrophages and to exert obvious effect upon the macrophage function. The specificity of used antisera was confirmed by findings obtained with fixed macrophages.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D000918:Antibody Specificity; D002462:Cell Membrane / Q000276:immunology; D007106:Immune Sera; D008247:Lysosomes / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D051379:Mice
D000906:Antibodies; D007106:Immune Sera
Proniknovenie antilizosomnykh syvorotok v makrofagi i lokalizatsiia antilizosomnykh antitel na ikh struktyrakh