title: [Activity of intestinal disaccharidases in human aging].
abstract: In 59 persons of advanced (60-74 years) and in 17 others of senile (75-89 years) age the activity of disaccharides in the small intestine was studied. In the past history of all the examinees no affections of the gastro-intestinal tract were recorded. As controls 26 healthy subjects aged 20-26 were examined. It was noted that the activity of maltase in the duodenal mucosa declined in advanced age and of maltase, lactase and saccharase - in senility. In jejunal mucosa the activity of maltase and lactase proved less active in persons of senile age. The reduced activity of intestinal disaccharides is attended by atrophy of the jejunal mucosa.
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging; D001284:Atrophy; D004186:Disaccharidases / Q000378:metabolism*; D004386:Duodenum / Q000201:enzymology; D005696:Galactosidases / Q000378:metabolism; D005959:Glucosidases / Q000378:metabolism; D006801:Humans; D007413:Intestinal Mucosa / Q000201:enzymology; D007421:Intestine, Small / Q000201:enzymology*; D007583:Jejunum / Q000201:enzymology; D008875:Middle Aged; D013393:Sucrase / Q000378:metabolism
chemical_list: D004186:Disaccharidases; D005696:Galactosidases; D005959:Glucosidases; D013393:Sucrase
vernacular_title: Aktivnost' kishechnykh disakharidaz pri starenii cheloveka