title: [Functional state of the cardiovascular system in experimental acute occlusion of the terminal segment of the aorta].
abstract: In 30 experiments on dogs a study was conducted of the pathophysiological mechanisms of the disorders in central haemodynamics and myocardial contractility during an acute occlusion of the terminal aorta and after reestablishment of the circulation in the diseases extremities. In response to the occlusion an elevation was noted in the total peripheral resistance, in the force and rate of the cardiac contractions, and a compensatory hyperfunction of the heart developed. By 6 hours of the occlusion the total peripheral resistance increased, the force and rate of the cardiac contractions decreased, the myocardial tension increased, the external work of the heart decreased, and myocardial hypodynamy developed. In 45 min following the restoration of the circulation a reduction of the total peripheral resistance was observed, the myocardial contractility was inhibited, the phase structure of the cardiac cycle was disturbed. A further observation for 45 min failed to reveal any changes in the indices of cardio- and haemodynamics, the phase structure of the cardiac contractions and myocardial contractility, as compared to the data obtained in the preceeding study.
mesh_terms: D000208:Acute Disease; D000818:Animals; D001011:Aorta / Q000503:physiopathology; D001018:Aortic Diseases / Q000503:physiopathology*; D001810:Blood Volume; D002302:Cardiac Output; D002306:Cardiac Volume; D002496:Central Venous Pressure; D004285:Dogs; D004617:Embolism / Q000503:physiopathology*; D005260:Female; D006321:Heart / Q000503:physiopathology*; D008297:Male; D009200:Myocardial Contraction; D014655:Vascular Resistance
vernacular_title: Funktsional'noe sostoinaie serdechno-sosudistoĭ sistemy pri ostroĭ okkliuzii terminal'nogo otdela aorty v eksperimente