[Mechanism for the liberation of duodenal gastrin in the dog].
The mechanisms of duodenal gastrin release were studied in 13 mongrel dogs after selective mucosal antrectomy: Vagal stimulation with insulin and local perfusion with acetylcholine at pH 7 resulted in a significant increase of the serum gastrin level taken from the pancreatico-duodenal vein. No significant amounts were detected after vagal stimulation with 2-deoxy-d-glucose, local perfusion with acetylcholin at pH 1, 5 nor after duodenal distension with 20, 40 and 120 cm water.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D004285:Dogs; D004386:Duodenum / Q000378:metabolism*; D005260:Female; D005755:Gastrins / Q000097:blood / Q000378:metabolism*; D007328:Insulin / Q000494:pharmacology; D008297:Male; D013268:Stimulation, Chemical; D014630:Vagus Nerve / Q000187:drug effects
D005755:Gastrins; D007328:Insulin; D000109:Acetylcholine
Mechanismen zur Freisetzung des duodenalen Gastrins beim Hund