Plasma tryptophan transport in normal and depressed subjects.
Depressed patients have a delayed clearance of i.v. injected labelled 1-tryptophan. A high affinity binding for the amino acid and a derangement of transport or distribution to tissues in the depressed are suggested as possible mechanisms.
D003863:Depression / Q000097:blood*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D013997:Time Factors; D014364:Tryptophan / Q000008:administration & dosage / Q000097:blood*
D014364:Tryptophan