Inhibitory effect of beta-hydroxyglutamic acid on a molluscan giant neurone.
We found a spontaneously firing neurone, inhibited by beta-hydroxy(erythro)-L-glutamic acid, identified in the subesophageal ganglia of an African giant snail (Achatina fulica Férussac), although this neurone is not sensitive to L-glutamic acid. We suggest that beta-hydroxy(erythro)-L-glutamic acid may be a putative inhibitory synaptic transmitter of the identified molluscan neurone.
D000818:Animals; D005971:Glutamates / Q000494:pharmacology*; D006880:Hydroxy Acids / Q000494:pharmacology; D008564:Membrane Potentials / Q000187:drug effects; D008974:Mollusca; D009474:Neurons / Q000187:drug effects* / Q000502:physiology
D005971:Glutamates; D006880:Hydroxy Acids; C011859:hydroxyglutamic acid