title: [Experimental investigation of the effects of estriol on menopausal symptoms (author's transl)].
abstract: The mechanical writing scales are micromotor method of investigation of psychomotor discoordination capable of producing objective records of menopausal symptoms. With this method, the therapeutic effect of estriol on the menopausal symptoms can be recorded. Changes in the micromotor symptoms such as reduction in the time of writing, a decrease in the unphysiologically high writing pressure and a decrease of in inhibition and relaxation symptoms show clearly that estriol enhances a co-ordination of the motor processes of writing. The positive effects of estriol on the psychomotor co-ordination are demonstrated in the improvement of the menopausal symptoms and the improvement of the vaginal cytology. Uterine bleeding is absent since estriol has a low endometriopic action.
mesh_terms: D002979:Climacteric / Q000187:drug effects*; D004964:Estriol / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006236:Handwriting; D006801:Humans; D008875:Middle Aged; D009129:Muscle Tonus / Q000187:drug effects; D009461:Neurologic Manifestations; D011596:Psychomotor Disorders / Q000175:diagnosis / Q000188:drug therapy; D014621:Vagina / Q000166:cytology / Q000187:drug effects
chemical_list: D004964:Estriol
vernacular_title: Experimentelle Darstellung der Wirkung von Ostriol im Klimakterium