Anti-reticulin antibody in jejunal juice in coeliac disease.
Anti-reticulin antibody has been demonstrated in the jejunal juice of eight out of fourteen (57%) untreated coeliac patients, one out of twelve (8%) patients with normal jejunal biopsies and none of ten normal control subjects. The jejunal juice antibody was invariably of the IgA class. It is suggested that the presence of anti-reticulin antibody in the jejunal juice in coeliac disease supports the hypothesis that this antibody is secreted in response to reticulin antigens present in the diet.
D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000032:analysis*; D002446:Celiac Disease / Q000276:immunology*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007419:Intestinal Secretions / Q000276:immunology*; D007583:Jejunum / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012155:Reticulin / Q000276:immunology*
D000906:Antibodies; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012155:Reticulin