[Lipoid dermatoarthritis (multicentric reticulohistiocytosis) (author's transl)].
The case of a 10-year-old girl with an infrequently observed lipid dermatoarthritis is reported. This is a systemic disease of unknown etiology characterized by a nodular eruption of the skin, mucosa and synovia, resulting in destructive arthritis and disfigurement of the facies. Biopsy of a nodule, whether from skin or synovia, discloses a cellular infiltrate consisting of histiocytes and multinucleated giant cells with lipid inclusions. No effective treatment is known.
D001168:Arthritis / Q000150:complications / Q000473:pathology*; D002648:Child; D002908:Chronic Disease; D005260:Female; D006023:Glycoproteins / Q000032:analysis; D006644:Histiocytes; D006801:Humans; D006833:Hydrarthrosis / Q000150:complications; D008055:Lipids / Q000032:analysis; D010743:Phospholipids / Q000032:analysis; D012871:Skin Diseases / Q000150:complications / Q000473:pathology; D013583:Synovial Membrane / Q000473:pathology
D006023:Glycoproteins; D008055:Lipids; D010743:Phospholipids
Lipoiddermatoarthritis (multizentrische Reticulohistiocytose)