[Effect of HL-A system antigen differences on the specificity of produced anti-leukocyte antibodies].
In Rh-negative volunteers immunized for development of anti-D antibodies the specificity of developed anti-leucocyte antibodies was determined. The specificity of these antibodies was analysed in relation to HL-A antigenic differences determined in donors and recipients. The antigenic power of sublocus II was found to be superior to that of sublocus I. Another observation was more frequent production of cross-reacting antibodies. A trial of analysis of these volunteers in whom no antileucocyte antibodies developed during immunization with blood was undertaken.
D000917:Antibody Formation; D000918:Antibody Specificity; D001782:Blood Donors; D003429:Cross Reactions; D006649:Histocompatibility Antigens; D006801:Humans; D007114:Immunization; D007962:Leukocytes / Q000276:immunology*
D006649:Histocompatibility Antigens
Wpływ róznic antygenowych układu HL-A na swoistość wytwarzanych przeciwciał anty-leukocytarnych