title: [Exo- and endocrine testicular function in the aging man].
abstract: In males over 60 years of age FSH excretion remains within the same range, whilst LH secretion increases significantly. Plasma testosterone and the biological active testosterone fraction decreases whilst at the same time the percentage of protein bound biological inactive testosterone increases. The androgen dependent target tissues become less sensitive to testosterone. The metabolic clearance rate for testosterone decreases. Spermatogenesis seems to stay intact in male senescence but exhaustive research in this field is not available.
mesh_terms: D000328:Adult; D000367:Age Factors; D000375:Aging; D004967:Estrogens / Q000378:metabolism; D005640:Follicle Stimulating Hormone / Q000096:biosynthesis / Q000378:metabolism; D006801:Humans; D007986:Luteinizing Hormone / Q000096:biosynthesis / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D013091:Spermatogenesis; D013094:Spermatozoa / Q000502:physiology; D013737:Testis / Q000502:physiology*; D013739:Testosterone / Q000096:biosynthesis / Q000378:metabolism
chemical_list: D004967:Estrogens; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
vernacular_title: Exo- und endokrine Hodenfunktion beim alternden Mann