Histologic host response to primary methylcholanthrene-induced sarcomas in rats immunized with allogeneic tumors.
Lymphocytic infiltration was observed in 44 of 51 (86%) 3-methylcholanthrene (MCA)-induced sarcomas in rats which had been intensively immunized with allogeneic tumors. Eleven of 29 (38%) tumors with intense lymphocytic infiltration and 5 of 15 (33%) tumors with moderate lymphocytic infiltration were "negative" in autologous transplantation. On the other hand, all of 7 tumors accompanied with slight or no lymphocytic infiltration were "positive".
D000818:Animals; D005260:Female; D006084:Graft Rejection; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008748:Methylcholanthrene; D009368:Neoplasm Transplantation; D051381:Rats; D012513:Sarcoma, Experimental / Q000139:chemically induced / Q000276:immunology* / Q000473:pathology; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous
D008748:Methylcholanthrene