title: Calculation of predictive odds for possible carriers of heamophilia.
abstract: Betting odds for possible carriers of haemophilia have been calculated using data derived from normal and known carrier populations. For each possible carrier the concentration of factor VIII-related antigen and factor VIII biological activity was measured and used to determine the probability of the individual being a carrier. The calculations indicated that, of the 32 possible carriers, 11 were likely to be normal (odds of more than 5:1) while 11 were likely to be haemophilia carriers (again odds of more than 5:1).
mesh_terms: D000941:Antigens / Q000032:analysis; D005169:Factor VIII / Q000032:analysis; D005260:Female; D006467:Hemophilia A / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D011336:Probability; D011338:Probability Theory
chemical_list: D000941:Antigens; D005169:Factor VIII