title: Measurement of gastric emptying time--a comparative study between nonisotopic aspiration method and new radioisotopic technique.
abstract: A comparative study between modified conventional saline load test and the more recently introduced radioisotopic method was run in 8 normal volunteers. Each subject underwent at least three studies by each of the two methods: (1) aspiration method of Goldstein and Boyle incorporating our modification, and (2) an isotopic method employing a gamma camera with a computer. A liquid meal of isotonic saline was used with or without (997) MTc-DTPA. The results indicated that the gastric emptying T 1/2 (8.8 +/- 3.5 min) obtained by saline load test was shorter than that obtained by isotopic method (12 +/- 3 min). This discrepancy was most likely due to inherent error (incomplete aspiration of the gastric fluid) in the former method giving rise to a false faster emptying time. Moreover, the variations in T 1/2 value in the same individual was much more in the aspiration method than it was in the isotopic method.
mesh_terms: D000328:Adult; D005767:Gastrointestinal Diseases / Q000175:diagnosis; D005773:Gastroscopy; D006801:Humans; D008722:Methods; D011877:Radionuclide Imaging; D012965:Sodium Chloride; D013270:Stomach / Q000502:physiology*; D013667:Technetium
chemical_list: D012965:Sodium Chloride; D013667:Technetium