title: [Aplastic anemia-a preleukemic stage (author's transl)].
abstract: In a group of 44 patients with primary and secondary aplastic anemia, four (9%) developed an acute leukemia. Cytological changes that pointed to a preleukemia were not observed during the preleukemic stage. The possibility is discussed whether a aplastic anemia and a preleukemia can be distinguished by cytological, cytochemical and cytogenetic tests, by agar-culture technique, liquid-culture and determination of reverse transcriptase.
mesh_terms: D000208:Acute Disease; D000328:Adult; D000741:Anemia, Aplastic / Q000150:complications*; D001856:Bone Marrow Examination; D005260:Female; D006801:Humans; D007938:Leukemia / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions
vernacular_title: Panmyelopathie - ein präleukämisches Stadium?