[Study of the carbohydrate content in the mycelia of an active strain producing oxytetracycline and in an inactive mutant].
The content of carbohydrates in the mycelium of the active strain and inactive mutant of the oxytetracycline-producing organism under conditions favourable (starch medium) and unfavourable (glucose medium) for the antibiotic biosynthesis was studied. The mycelium of both organisms was fractionated and carbohydrate distribution according to the mycelium fractions and carbohydrate content in every fraction were investigated. No significant differences were observed between the active strain and inactive mutant with respect to the characteristics studied. The carbon source in the medium had the dominating effect on the chemical composition of the mycelium. The mycelium of both strains grown on the starch medium contained much more carbohydrates than that grown on the glucose medium. The carbohydrates of the mycelium grown on the starch medium were mainly found in fraction III and must be represented by polysaccharides.
D002241:Carbohydrates / Q000032:analysis*; D003470:Culture Media; D009154:Mutation; D010118:Oxytetracycline / Q000096:biosynthesis*; D011134:Polysaccharides / Q000032:analysis; D013302:Streptomyces / Q000032:analysis* / Q000378:metabolism
D002241:Carbohydrates; D003470:Culture Media; D011134:Polysaccharides; D010118:Oxytetracycline
Issledovanie soderzhaniia uglevodov v mitselii aktivnogo shtamma--pprodutsenta oksitetratsiklina--i neaktivnogo mutanta