title: Antigenic properties of subcellular fractions from canine pancreas: development of a zymogen membrane specific antibody.
abstract: Immunization of rabbits with a membrane preparation from dog pancreas produced precipitating antibody against an antigen present in the pancreas of several mammals. This antigen appears to be organ-specific but not species-specific and is localized in the pancreatic zymogen granule membrane fraction. It is thought to represent glycoproteins of mol wt 70,000-90,000 as well as a smaller species of mol wt less than 10,000.
mesh_terms: D000818:Animals; D001323:Autoantibodies; D002458:Cell Fractionation; D003429:Cross Reactions; D003594:Cytoplasmic Granules / Q000276:immunology*; D004285:Dogs; D004792:Enzyme Precursors; D006023:Glycoproteins / Q000276:immunology; D008566:Membranes / Q000276:immunology; D010179:Pancreas / Q000276:immunology*; D011817:Rabbits
chemical_list: D001323:Autoantibodies; D004792:Enzyme Precursors; D006023:Glycoproteins