Fibre function and perception during cutaneous nerve block.
In awake human subjects, neural responses in cutaneous nerves to electrical stimulation were recorded with intrafascicular tungsten micro-electrodes. Changes in the activity of individual fibre groups during blocking procedures were recorded and correlated with simultaneous alterations in the perception of standardized stimuli. Light touch sensibility in hairy skin was mediated by A-beta-gamma fibres, cold and pinprick by A-delta fibres and warmth and dull pain by C fibres.
D000200:Action Potentials; D000328:Adult; D000772:Anesthesia, Local; D006801:Humans; D008875:Middle Aged; D009407:Nerve Block; D009413:Nerve Fibers, Myelinated / Q000502:physiology; D009431:Neural Conduction; D009474:Neurons / Q000502:physiology*; D010465:Perception / Q000502:physiology*; D011312:Pressure; D012867:Skin / Q000294:innervation*; D013697:Thermosensing / Q000502:physiology; D014110:Touch / Q000502:physiology