[The effect of parenteral administration of amino acids and their mixtures the secretory activity of the stomach].
Experiments on dogs with gastric fistula after Basov and Pavlov pouch demonstrated that introduction into the blood by the drip method of solutions of L-amino acids and their mixtures tends to induce gastric secretion. This effect is produced by nonessential acids somewhat more intensively than by essential ones. A complete mixture of amino acids yields the least secretory effect. Among individual amino acids under study, taken in isomolar quantities, the most intensive gastric secretion induce glycin, alanine and proline. The least active in this respect proved to be lysine.
D000409:Alanine / Q000494:pharmacology; D000596:Amino Acids / Q000008:administration & dosage / Q000494:pharmacology*; D000601:Amino Acids, Essential / Q000494:pharmacology; D000818:Animals; D004285:Dogs; D005747:Gastric Fistula; D005750:Gastric Juice / Q000378:metabolism; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism*; D005998:Glycine / Q000494:pharmacology; D007263:Infusions, Parenteral; D011392:Proline / Q000032:analysis; D012636:Secretory Rate / Q000187:drug effects; D013329:Structure-Activity Relationship
D000596:Amino Acids; D000601:Amino Acids, Essential; D011392:Proline; D000409:Alanine; D005998:Glycine
Vliianie parenteral'no vvodimykh aminokislot i ikh smeseí na sekretornuiu deiatel'nost' zheludka