Lichenoid eruption following penicillamine. A case report with some biochemical observations.
The phenomenon of lichenoid eruptions following medication with antimalarial, anti-arthritis and antibacterial medication is well documented in the literature. We report here the first case to be described as a result of anti-arthritis treatment with penicillamine, together with some biochemical studies of the effect of this compound on the enzyme glucose-6-phosphate dehydrogenase.
D000328:Adult; D005954:Glucosephosphate Dehydrogenase / Q000037:antagonists & inhibitors; D006801:Humans; D008010:Lichen Planus / Q000139:chemically induced* / Q000201:enzymology / Q000473:pathology; D008297:Male; D010396:Penicillamine / Q000009:adverse effects*
D005954:Glucosephosphate Dehydrogenase; D010396:Penicillamine