title: The influence of age and sex on skin thickness, skin collagen and density.
abstract: Forearm skin collagen, dermal thickness and collagen density were measured in a large number of normal subjects as a standard reference for future studies. Skin collagen decreased with age and was less in the females at all ages. There is a direct relationship between skin collagen and dermal thickness but variations in collagen density in disease limit the use of dermal thickness as a guide to changes in its collagen content.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D003094:Collagen / Q000032:analysis*; D005260:Female; D005542:Forearm / Q000033:anatomy & histology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D012867:Skin / Q000032:analysis / Q000033:anatomy & histology*
chemical_list: D003094:Collagen