[A comparative study of the functional characteristics of thrombocytes at different stages of individual development].
A comparative study of ADP-induced aggregation was made in adult rabbits' intact and refractory platelets and in 7-day rabbits' platelets in vitro. Platelets of the young animals resembled refractory those of adults. The effect of ADP on platelets in vivo did not depend on the age of animals. Changes in platelet population composition of adult and 7-day rabbits during standard isolation procedure were compared. The platelets in PRP of young rabbits were damaged to a greater extent than those of adult animals. It is suggested that the refractory state of young animal platelets in PRP as obtained with the standard technique, could be attributed to their decreased resistance against mechanical forces.
D000244:Adenosine Diphosphate; D000818:Animals; D001792:Blood Platelets / Q000502:physiology*; D006128:Growth; D010812:Physical Stimulation; D010974:Platelet Aggregation; D011817:Rabbits; D013921:Thrombocytopenia / Q000139:chemically induced
D000244:Adenosine Diphosphate
Sravnitel'noe issledovanie funktsional'nykh osobennosteĭ trombotsitov na otdel'nykh étapakh individual'nogo razvitiia