[The effects of the pathogenic influence of botulin toxin on different types of spinal motor neurons].
The motor neuron cells of the lumbosacral region were investigated in the spinal cord of cat with the local botulin paralysis. Development of this paralysis was followed by reduction of the membrane potential, of the amplitude of antidromic AP, mono- and polysynaptic EPSP, a fall of the input resistance and by an increase in the level of the critical depolarization of the somatic membrane of the phasic motor neurons of the damaged segments in the spinal cord. Excitation of the tonic motor neurons was not greatly altered in the dynamics of local botulism.
D000200:Action Potentials; D000818:Animals; D002415:Cats; D008564:Membrane Potentials; D009046:Motor Neurons / Q000503:physiopathology*; D013116:Spinal Cord / Q000503:physiopathology*; D013570:Synaptic Membranes
Effekty patogennogo deĭstviia botulinicheskogo toksina na raznye tipy spinal'nykh motoneĭronov