title: [Chronic percutaneous salicylic acid poisoning].
abstract: The uncontrolled, long-term (18 months), widespread (almost 3/4 total body skin surface), application of a concentrated (10%) salicylic acid ointment in a 62 year old psoriatic female led to chronic percutaneous salicylism. Salicylic acid levels in the urine (200 mg %) and serum (223 mg %), the highest values ever recorded in this type of intoxication, contrasted with the discrete clinical picture. The acute and chronic percutaneous salicylism is discussed with a review of the literature. It is warned against the uncontrolled use of topicals containing salicylic acid.
mesh_terms: D000287:Administration, Topical; D002908:Chronic Disease; D005260:Female; D006207:Half-Life; D006801:Humans; D007700:Kinetics; D008875:Middle Aged; D009824:Ointments; D011565:Psoriasis / Q000188:drug therapy; D012459:Salicylates / Q000009:adverse effects / Q000378:metabolism / Q000506:poisoning* / Q000627:therapeutic use; D012651:Self Medication
chemical_list: D009824:Ointments; D012459:Salicylates
vernacular_title: Die chronisch perkutane Salizylsäureintoxikation