[Effect of hyperoxia on calcium transport in mitochondria of brain and liver].
The active and passive transport of radioactive calcium was studied in experiments on the brain and liver mitochondria, homogenates of brain and erythrocytes of albino rats subjected to the toxic effect of oxygen under pressure. The processes of the Ca2+ active transport preparations under examination are established to be inhibited after the effect of hyperoxia. The passive transport is considerably less dependent on the previous effect of oxygen. A conclusion is drawn on the prevailing sensitivity of the calcium energy-dependent transport to the damaging effect of hyperoxia.
D000818:Animals; D001692:Biological Transport; D001693:Biological Transport, Active; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism*; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D010100:Oxygen / Q000494:pharmacology*; D010313:Partial Pressure; D051381:Rats
D010100:Oxygen; D002118:Calcium
Vplyv hiperoksii na transport akl'tsiiu v mitokhondriiakh mozku i pechinky