The narcotic cue: evidence for the specificity of the stimulus properties of narcotic drugs.
Various non-narcotic drugs with intrinsic stimulus properties were found not to be generalized with fentanyl treatment in rats trained to discriminate fentanyl (0.04 mg/kg, s.c., t-30') from its solvent (s.c., t-30'). In contrast, five typical narcotic analgesics yielded dose-dependent generalization with fentanyl treatment. The results evidence the specific character of the narcotic cue in rats.
D000818:Animals; D003463:Cues; D004193:Discrimination Learning / Q000187:drug effects; D005283:Fentanyl / Q000494:pharmacology; D008297:Male; D009294:Narcotics / Q000494:pharmacology*; D051381:Rats; D013268:Stimulation, Chemical
D009294:Narcotics; D005283:Fentanyl