Specific binding sites for 5-hydroxytryptamine on rat blood platelets.
5-Hydroxytryptamine changes the shape of rat blood platelets by combination with a cinanserin-sensitive receptor which is not associated with the active uptake of 5-hydroxytryptamine. Binding of 5-hydroxy[3H]tryptamine to platelets at 4 degrees C demonstrates the presence of three saturable sites, and the highest-affinity site is apparently this 5-hydroxytryptamine receptor.
D000818:Animals; D001665:Binding Sites; D001792:Blood Platelets / Q000378:metabolism*; D002928:Cinanserin; D051381:Rats; D011955:Receptors, Drug; D012701:Serotonin / Q000097:blood*
D011955:Receptors, Drug; D012701:Serotonin; D002928:Cinanserin