[Isoenzymic composition of glucose-6-phosphate dehydrogenase of subcellular fractions of rabbit tissues under alloxan diabetes].
The isoenzymes of glucose-6-phosphate dehydrogenase (G-6-PD, EC 1.1.1.49) was studied in hyaloplasm and mitochondria of the liver, myocardium, skeletal muscle, spleen and adrenals of alloxan diabetic rabbits. The most significant changes were found in the liver hyaloplasm: one of the minor isoenzymes, isoenzyme "C", disappears and the zone of the main isoenzyme "E" decreases significantly in comparison with the control. It was found that the intensity of these changes depends on the glycemia level in the diabetic animals.
D000311:Adrenal Glands / Q000201:enzymology; D000818:Animals; D003593:Cytoplasm / Q000201:enzymology; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism*; D007527:Isoenzymes / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D008928:Mitochondria / Q000201:enzymology; D008930:Mitochondria, Liver / Q000201:enzymology; D008931:Mitochondria, Muscle / Q000201:enzymology; D009132:Muscles / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D011817:Rabbits; D013154:Spleen / Q000201:enzymology; D013347:Subcellular Fractions / Q000201:enzymology
D007527:Isoenzymes; D005954:Glucosephosphate Dehydrogenase
Izofermentnyĭ sklad hliukozo-6-fosfatfehidrohenazy subklitynnykh fraktsiĭ tkanyn kroliv za aloksanovoho diabetu