title: The effect of stable strontium on the incorporation and metabolism of radioactive strontium in young and adult rabbit bones.
abstract: The experiments were performed on 5-, 8-, 12- and 14 months old rabbits. The effect of stable strontium enriched diet on the bone tissue formation (apposition) and on physiocochemical processes consisting in ion exchange were studied using radioactive isotopes: Sr-85 and Ra-226 and tetracycline. The results of kinetic and autoradiographic studies and micoscopical analysis of bone preparations suggest that stable strontium inhibits the mineralization of newly formed bone tissue without affecting the physico-chemical processes related to ion exchange.
mesh_terms: D000367:Age Factors; D000818:Animals; D001345:Autoradiography; D001846:Bone Development / Q000528:radiation effects*; D001842:Bone and Bones / Q000378:metabolism*; D005527:Food, Fortified; D007474:Ion Exchange; D007700:Kinetics; D011817:Rabbits; D011830:Radiation Effects; D011883:Radium; D013324:Strontium / Q000008:administration & dosage / Q000494:pharmacology*; D013326:Strontium Radioisotopes; D013752:Tetracycline
chemical_list: D013326:Strontium Radioisotopes; D013752:Tetracycline; D011883:Radium; D013324:Strontium