[Modifications of phosphocalcic metabolism in patients treated with anticonvulsivants (author's transl)].
Differences in the seric values of Ca, P and alk. phosphatase before and after 12 to 18 months of anticonvulsant therapy in 45 patients are reported. They were significant for alk. phosphatase in patients under either barbiturates or barbiturates associated with hydantoin. For calcium they were significant in patients treated with barbiturate plus hydantoins and either one of these plus other drugs. It is assumed that supplementary vitamin D can be necessary in these group of patients.
D000469:Alkaline Phosphatase / Q000378:metabolism; D001463:Barbiturates / Q000009:adverse effects* / Q000627:therapeutic use; D002128:Calcium Metabolism Disorders / Q000139:chemically induced*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006827:Hydantoins / Q000009:adverse effects* / Q000627:therapeutic use; D007223:Infant; D008297:Male; D010760:Phosphorus Metabolism Disorders / Q000139:chemically induced*; D012640:Seizures / Q000188:drug therapy*
D001463:Barbiturates; D006827:Hydantoins; D000469:Alkaline Phosphatase
Modificaciones del metabolismo fosfocálcico en pacientes tratados con anticonvulsivantes