Lack of effect of methyl-ergonovine on postpartum lactation.
There is little information about the action of ergot derivatives other than bromocriptine (CB 154) on plasma prolactin and milk secretion in human beings. In a recent report it has been suggested that ergonovine might interfere with lactation when administered post partum. The present study shows that methyl-ergonovine (Methergine), a closely related compound, has no action on prolactin or milk secretion as measured in a group of 10 breast feeding mothers in comparison with another 10 untreated puerperas.
D005260:Female; D006801:Humans; D007774:Lactation / Q000187:drug effects*; D008755:Methylergonovine / Q000494:pharmacology*; D049590:Postpartum Period / Q000187:drug effects*; D011247:Pregnancy
D008755:Methylergonovine