Core antibodies and other parameters of hepatitis B virus infection in a tropical population.
HBsAg (80% of ay subtype) was detected with radioimmunoassay in 10% of a sample of the healthy population in Mopti, Mali, and in 6% with counterelectrophoresis. Anti-HBs was detected in approximately 57% of adults, and anti-HBc in 50%. Anti-HBs was not always detectable in anti-HBc positive sera with the methods used, and vice versa. This accounted for up to 85% of an adult group showing anti-HBs, anti-HBc, or both. While anti-HBc percentages climbed more gradually with age, and 'adult' percentage of anti-HBs was reached at about 3 years of age, and there were no significant differences in the age distribution of HBsAg.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000906:Antibodies; D002648:Child; D002675:Child, Preschool; D003168:Complement Fixation Tests; D003378:Counterimmunoelectrophoresis; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology*; D006510:Hepatitis B Antibodies / Q000032:analysis; D006511:Hepatitis B Antigens / Q000032:analysis; D006801:Humans; D007223:Infant; D008297:Male; D008302:Mali; D011863:Radioimmunoassay; D012737:Sex Factors
D000906:Antibodies; D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens