title: [Circadian periodicity of blood coagulation system indices and the hormonal activity of the adrenals in healthy persons (under conditions of rest and of stressed work)].
abstract: 13 patients with the heart ischemic disease (HID) were examined in conditions of a relative rest (hospital) and 20 patients - during an intensive day work. Within the 24-hr rhythm of gemocoagulation parameters, 3 phases were distinguished (conventionally): I a tendency to hypercoagulation at 0-3-6 a.m.; II the most safe period at 9 a.m.; III an increased ability of coagulation at 12-3-6-9 p.m. During the intensive day work, hypercoagulative shifts become more obvious and the anticoagulating system becomes activated at the I and the III phases. Within the 24: hr rhythm of the plasma fibrinolytic activity, 2 phases were distinguished (conventionally): I low activity at 0-3-6-9-12 a.m.; II sufficient activity at 3-6-9 p.m. During the intensive day work fibrinolytic activity increases, and the character of 24-hr rhythm preserves. Within the 24-hr rhythm of the adrenal hormonal activity, 3 phases were distinguished (conventionally): I a reduced activity at 0-3-6 a.m.; II high activity at 9 a.m.; III high enough activity at 12-3-6-9 p.m. In conditions of intensive day work the 24-hr rhythm of the adrenal hormonal activity does not change.
mesh_terms: D015065:17-Hydroxycorticosteroids / Q000652:urine; D000305:Adrenal Cortex Hormones / Q000502:physiology*; D000311:Adrenal Glands / Q000502:physiology*; D000328:Adult; D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D002940:Circadian Rhythm; D004837:Epinephrine / Q000652:urine; D005172:Factor XI / Q000032:analysis; D005174:Factor XII / Q000032:analysis; D005176:Factor XIII / Q000032:analysis; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D005342:Fibrinolysis; D006262:Health; D006493:Heparin; D006801:Humans; D008297:Male; D009638:Norepinephrine / Q000652:urine; D010973:Platelet Adhesiveness; D011516:Prothrombin / Q000032:analysis; D012146:Rest; D013312:Stress, Physiological / Q000503:physiopathology; D013917:Thrombin / Q000032:analysis; D013997:Time Factors; D014937:Work
chemical_list: D015065:17-Hydroxycorticosteroids; D000305:Adrenal Cortex Hormones; D011516:Prothrombin; D005174:Factor XII; D005340:Fibrinogen; D006493:Heparin; D005172:Factor XI; D005176:Factor XIII; D013917:Thrombin; D009638:Norepinephrine; D004837:Epinephrine
vernacular_title: Sutochnaia periodika pokazateleĭ sistemy svertyvaniia krovi i gormonal'naia aktivnost' nadpochechnikov u zdorovykh lits (v usloviiakh i pri napriazhennoĭ rabote)