[Influence of labor induced by prostaglandins on the metabolism and blood coagulation system of the mother and child during labor].
22 pregnancies at term were terminated by dilatation of the uterine cervix, low amniotomy, and by intravenous administration of PGF2alpha or PGE2. The average infusion time was 4 hours 10 minutes, and the average total dose of PGF2alpha amounted to 2,0 mg and of PGE2 0,2 mg. Parameters of acid-base changes, carbohydrate and energic state changes, gas metabolism, and changes in coagulation and fibrinolysis in mother and in fetus were analyzed during labor and after birth. Labor activity and fetal cardiac action were monitored cardiotocographically. Checked against 50, and for the coagulation 12 uncomplicated spontaneous deliveries, we have found no disadvantageous changes in the parameters investigated.
D000136:Acid-Base Equilibrium / Q000187:drug effects; D001777:Blood Coagulation / Q000187:drug effects*; D004734:Energy Metabolism / Q000187:drug effects*; D005260:Female; D005333:Fetus / Q000187:drug effects; D005342:Fibrinolysis / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced; D007743:Labor, Obstetric / Q000187:drug effects*; D008431:Maternal-Fetal Exchange / Q000187:drug effects; D011247:Pregnancy; D011453:Prostaglandins / Q000494:pharmacology*
D011453:Prostaglandins
Einfluss prostaglandininduzierter Wehen auf den Stoffwechsel und das Gerinnungssystem von Mutter und Kind unter der Geburt