title: [Studies of cardiovascular damage in subjects with altered purine metabolism].
abstract: The percentage of arteriosclerotic changes with or without dyslipaemic humoral deviation was studied in a sample of subjects with altered purine metabolism of various corresponding clinical expression and the percentage of hyperuricaemia in a homologous sample of arteriosclerotics. It is concluded that a definite dependent relationship between arteriosclerotic lesions and abnormality of purine metabolism remains a hypothesis and that between the two metabolic alterations there is a more or less indirect associative, chronological and dysmetabolic involvement relationship.
mesh_terms: D000328:Adult; D000368:Aged; D001161:Arteriosclerosis / Q000209:etiology; D003327:Coronary Disease / Q000209:etiology*; D005260:Female; D006073:Gout / Q000150:complications*; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D002537:Intracranial Arteriosclerosis / Q000209:etiology; D050356:Lipid Metabolism; D008297:Male; D008659:Metabolic Diseases / Q000150:complications*; D008875:Middle Aged; D011687:Purines / Q000378:metabolism*
chemical_list: D011687:Purines
vernacular_title: Ricerche sulla compromissione cardiovascolare in soggetti con alterato metabolismo purinico