title: Survival and recovery of physiologic functions after early maternal separation in rats.
abstract: Fourteen-day-old rats separated from their mothers have greatly increased survival rates, if provided with a local heat source. Body weight, temperature, cardiac and respiratory rates declined for 3 days in all separated animals, and eye opening was delayed most in those separated at room temperature. In survivors, a second phase followed in which all measures rebounded to levels characteristic of normally mothered infants. Cardiac rate, having fallen 40 percent in the first days after separation, rose to levels higher than normally mothered infants at 21 and 30 days of age. Recovery was not clearly initiated by any singly system studied, although non-survivors showed greater weight and temperature loss and evidence of gross motor deficit during the separation response phase.
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development*; D001831:Body Temperature; D001835:Body Weight; D006339:Heart Rate; D008426:Maternal Deprivation; D009043:Motor Activity; D051381:Rats; D012119:Respiration