Intramolecular electron transport in human ferroxidase (caeruloplasmin).
The oxidation of reduced human ferroxidase by molecular O2 was studied in a stopped-flow spectrophotometer. It was shown that the two type 1 copper atoms behave differently in the absence of iron. The effect of iron on the kinetic parameters was investiagted. A working model for intramolecular electron transport in the enzyme is proposed.
D002570:Ceruloplasmin; D003300:Copper; D004579:Electron Transport; D006801:Humans; D007700:Kinetics; D008956:Models, Chemical; D010084:Oxidation-Reduction; D013053:Spectrophotometry; D013997:Time Factors
D003300:Copper; D002570:Ceruloplasmin