[Formation of spontaneous and immune rosettes by the cells of the thymus and other formations of the rabbit lymphoid system].
Only T1--RFC (rosette-forming cells) are revealed in the thymus of nonimmunized rabbits. Their number is 2--2.5 times less than in the palatine tonsils, submaxillary lymph nodes and the spleen. T2--RFC are present in these lymphoid formations. There is an increase in the T1--RFC in the thymus after the intravenous immunization of rabbits with sheep erythrocytes. In other lymphoid formations the correlation of the population of cells of the thymus origin altered as a result of increase in the number of T2--RFC. B--RFC accumulated in considerable amounts. Dynamics of T2 and B--RFC accumulation in the lymphoid formations corresponded to the highest antibody titres in the rabbit blood. In the formation of primary immune response the amount of the T1 and T2-RFC in the formations of rabbit lymphoid system depended on the dose of the antigen.
D000818:Animals; D002682:Chinchilla; D006388:Hemagglutinins / Q000032:analysis; D006460:Hemolysin Proteins / Q000032:analysis; D007104:Immune Adherence Reaction; D008198:Lymph Nodes / Q000276:immunology; D008221:Lymphoid Tissue / Q000276:immunology*; D014066:Palatine Tonsil / Q000276:immunology; D011817:Rabbits; D013154:Spleen / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology
D006388:Hemagglutinins; D006460:Hemolysin Proteins
Osobennosti formirovaniia spontannykh i immunykh rozetok kletkami timusa i drugikh obrazovaniĭ limfoidnoĭ sistemy krolikov