[Characteristics of messenger RNA for interferon and of interferon-inducing RNA isolated from Newcastle disease virus infected cells].
Two kinds of RNA capable of producing interferon in a heterologous cell system occur in the cells producing interferon in response to induction by Newcastle disease virus. One of them has messenger activity for interferon and is presented by a single-stranded structure with sedimentation constant of 10-22 S. This RNA appears to belong to cellular messenger RNA. The other is capable of inducing interferon production by heterogenous cells, resistant to treatment with RN-ase and has sedimentation constant greater than 35 S. In our opinion, this RNA is the primary replicative RNA of the virus-inducer.
D046508:Culture Techniques; D007372:Interferons / Q000096:biosynthesis*; D009522:Newcastle disease virus / Q000032:analysis* / Q000254:growth & development; D012333:RNA, Messenger / Q000032:analysis*; D012367:RNA, Viral / Q000032:analysis*; D014779:Virus Replication
D012333:RNA, Messenger; D012367:RNA, Viral; D007372:Interferons
Kharakteristika informatsionnoi RNK dlia interferona i interferonindutsiruiushchei RNK, vydelennykh is kletok, zarazhennykh virusom bolezni N'iukasia