Acute effect of hypophysectomy on the natriuresis following saline infusion in dogs.
The natriuresis following an i.v. isotonic saline loading corresponding to 10% of body wt. was markedly decreased after acute hypophysectomy, due to lowered urinary sodium concentration, in anaesthetized dogs. A role of the pituitary in such a homeostatic natriuresis is suggested.
D000818:Animals; D001794:Blood Pressure; D004285:Dogs; D005110:Extracellular Space; D005260:Female; D005919:Glomerular Filtration Rate; D007016:Hypophysectomy; D007263:Infusions, Parenteral; D008297:Male; D009318:Natriuresis; D010902:Pituitary Gland / Q000502:physiology; D012965:Sodium Chloride / Q000008:administration & dosage
D012965:Sodium Chloride