title: [The effect of brain hydrolysate on central nervous system structure].
abstract: The authors studied the action of "cerebrolysin" on the maturation and differentiation of cell elements in the brain cortex and hypophysis. Cerebrolysin was administered in doses from 0.005-0.025 ml daily during 4 days (beginning from the 4th, 7th or 10th day of postnatal life of the animals). Histological and electron microscopical studied demonstrated that in experimental groups of animals compared to control ones (intact) there is an earlier differentiation of the nervous cell structures and an accelerated formation of the cytoarchitechtonic fields in the brain cortex. The hypophysis has an earlier accumulation and increase of the amount of granular secretion.
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects / Q000254:growth & development; D008854:Microscopy, Electron; D009419:Nerve Tissue Proteins / Q000096:biosynthesis; D010902:Pituitary Gland / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D051381:Rats; D012270:Ribosomes / Q000378:metabolism; D013268:Stimulation, Chemical; D014020:Tissue Extracts / Q000494:pharmacology*
chemical_list: D009419:Nerve Tissue Proteins; D014020:Tissue Extracts
vernacular_title: O deĭstvii gidrolizata mozga na struktury tsentral'noĭ nervnoĭ sistemy