Confluent lymphoreticular aggregates in the bronchi of children--'mural bronchitis'.
A study of a random series of 503 lungs from children of all ages and comprising a cross-section of almost all deaths in children in Sheffield shows that 'mural bronchitis' is not seen at birth but increases progressively with post-natal age. These lesions bear no relationship to unexpected death in infancy. They are probably a normal component of children's lungs, and an indication of bronchus associated lymphoid tissue. There is a positive correlation between the presence of prominent lesions and long-standing history of respiratory symptoms.
D000293:Adolescent; D001249:Asthma / Q000150:complications; D001980:Bronchi / Q000473:pathology*; D001991:Bronchitis / Q000150:complications / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D006651:Histocytochemistry; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008168:Lung / Q000473:pathology; D008221:Lymphoid Tissue / Q000473:pathology*; D013398:Sudden Infant Death / Q000453:epidemiology / Q000209:etiology / Q000473:pathology