title: [Alterations in the activity of lactate dehydrogenase and its isoenzyme spectrum in the blood of patients with epilepsy].
abstract: The paper is concerned with the general activity of LDH and the spectre of its isoenzymes which was determined by different techniques in the blood serum of adult epileptic patients, epileptic children and adolescents between seizures, as well as in adult patients during and at different periods after covulsive fits. It was established that the general activity of LDH and the percent content of isoenzymes LDH-I in the blood serum of adult epileptic patients is less compared to epileptic children and adolescents and normals. During convulsive fits the general activity of LDH and LDH-I in the blood serum increases, which is indicative of an intensification of glycolytic processes.
mesh_terms: D000328:Adult; D000367:Age Factors; D004827:Epilepsy / Q000097:blood / Q000150:complications / Q000201:enzymology*; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
vernacular_title: Izmenenie aktivnosti laktatdegidrogenazy i spektra ee izofermentov v syvorotke krovi bol'nykh épilepsieĭ