title: Pelvic hemangiopericytoma. Report of 4 patients and review of the literature.
abstract: Review of the literature revealed 42 patients with uterine hemangiopericytoma (HPC) and nine with extrauterine tumors. Three additional patients with uterine and one with extrauterine are described. The primary treatment should be aggressive surgery, but high doses of irradiation and chemotherapy may be of benefit in extensive disease or recurrences. The prognosis of uterine HPC is better than that of the extrauterine tumors. Cells from the extrauterine tumor were grown in tissue culture. The culture consisted of two cell types resembling pericytes and endothelial cells. The cells in culture retain most of the ultrastructural characteristics of the in vivo tumor.
mesh_terms: D000328:Adult; D000368:Aged; D002196:Capillaries / Q000648:ultrastructure; D002478:Cells, Cultured; D004727:Endothelium / Q000648:ultrastructure; D005260:Female; D006393:Hemangiopericytoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D010386:Pelvic Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D011379:Prognosis; D012186:Retroperitoneal Neoplasms / Q000473:pathology* / Q000601:surgery