[Elimination of large pyroninophilic cells due to the effect of phytohemagglutinin].
Large pyroninophilic lymphocytes adsorbed on the surface of target-cells disappeared after phytohemagglutinin (PHA) addition. Incubation during 45 minutes in the presence of PHA did not reveal cisternas of the granular endoplasmatic reticulum and the number of mitochondrias decreased. The H3-thymidine-labeled cells were almost eliminated. There appeared population of small lymphocytes with even outline and clear cytoplasm, poor in organellas, with ribosomas freely scattered in it. After 24--48 hours of incubation they transformed into blasts, large cells with clear nucleus and clear cytoplasm in which no cisternas of granular endoplasmatic reticulum were revealed.
D000818:Animals; D003593:Cytoplasm / Q000187:drug effects; D004721:Endoplasmic Reticulum / Q000187:drug effects; D037102:Lectins / Q000494:pharmacology*; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects*; D051379:Mice; D008928:Mitochondria / Q000187:drug effects; D012270:Ribosomes / Q000187:drug effects; D013997:Time Factors
D037102:Lectins
Eliminatsiia bol'shikh pironinofil'nykh kletok pod deĭstviem fitogemaggliutinina