[Anemia in terminal kidney insufficiency: ferrokinetics, erythrocyte survival times and erythrocyte enzymes in chronic dialysis patients].
Radio-iron utilization was nearly normal in these patients, only bilateral nephrectomized patients showed a reduced radio-iron utilization. Red blood half-life span was shortened in all patients, well corresponding to the degree of anemia. Parameters of erythropoesis like plasma iron clearance, bone marrow transit time, erythron iron turnover, non erythron iron turnover and hemolysis iron turnover failed to quantitate disorders of red blood cell regeneration in these patients. No defect in red blood cell enzyme activity could be demonstrated. Enzymes of glycolysis were increased corresponding to the reduced erythrocyte half-life span.
D000743:Anemia, Hemolytic / Q000097:blood* / Q000209:etiology; D001853:Bone Marrow / Q000378:metabolism; D004905:Erythrocyte Aging; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000201:enzymology*; D004920:Erythropoiesis; D005260:Female; D006019:Glycolysis; D006801:Humans; D007501:Iron / Q000097:blood / Q000378:metabolism*; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000150:complications; D007700:Kinetics; D008297:Male; D009392:Nephrectomy; D006435:Renal Dialysis; D012156:Reticulocytes; D013727:Terminal Care
D007501:Iron
Anämie bei terminaler Niereninsuffizienz Ferrokinetik, Erythrozyten-Uberlebenszeit und Erythrozytenenzyme bei chronisch dialysierten Patienten