title: [Use of polidez for treating patients with endarteritis obliterans of the lower extremities].
abstract: To treat patients with chronic arterial occlusion of the lower extremities, the authors used 3% solution of low molecular polyvinyl alcohol in 0.9% sodium chloride solution-polydese. The substance was injected intravenously and intraarterially in a dosage of 10 ml per k Kg of weight. There was noted a good tolerance of the drug, and also the absence of toxic, pyrogenic and allergic reactions. In polydese therapy a marked improvement of the peripheral blood circulation was observed. The conducted clinical observations, laboratory studies have proved polydese to be the drug of a positive rheological effect.
mesh_terms: D000328:Adult; D001162:Arteriosclerosis Obliterans / Q000188:drug therapy; D001775:Blood Circulation / Q000187:drug effects; D001809:Blood Viscosity / Q000187:drug effects; D002784:Cholesterol / Q000097:blood; D002908:Chronic Disease; D004338:Drug Combinations; D004692:Endarteritis / Q000188:drug therapy*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D008970:Molecular Weight; D010952:Plasma Substitutes / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D011142:Polyvinyl Alcohol; D011143:Polyvinyl Chloride / Q000008:administration & dosage*; D011145:Polyvinyls / Q000008:administration & dosage*; D012965:Sodium Chloride / Q000008:administration & dosage*
chemical_list: D004338:Drug Combinations; D010952:Plasma Substitutes; D011145:Polyvinyls; C011324:polidez; D012965:Sodium Chloride; D011143:Polyvinyl Chloride; D011142:Polyvinyl Alcohol; D002784:Cholesterol
vernacular_title: Primenenie polideza dlia lecheniia bol'nykh obliteriruiushchim éndarteritom nizhnykh konechnosteĭ