[Participation of the cardiac sympathetic innervation in the occurrence of vagotomic and atropine tachycardia in anesthetized dogs].
The sympathetic nervous system's role in the post-vagotomy and atropin-induced tachycardia was studied in anesthetized dogs. Bilateral vagotomy was followed by 166% tachycardia while on exclusion of the heart sympathetic innervation (inderal or novocain injections into the right stellate ganglion) the bilateral vagotomy was accompanied by a considerably lesser tachycardia (33%). The i.v. atropine administration increased the heart rate by 177% whereas in the presence of inderal it increased the heart rate by 77% only. Thereupon, the post-vagotomy or atropin-induced tachycardia in anesthetized dogs was to a considerable extent associated with activation of the sympatho-adrenal system.
D000818:Animals; D001285:Atropine / Q000494:pharmacology*; D004285:Dogs; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000187:drug effects / Q000502:physiology*; D006339:Heart Rate / Q000187:drug effects; D008026:Ligation; D008297:Male; D009020:Morphine; D009407:Nerve Block; D010424:Pentobarbital; D011343:Procaine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D013564:Sympathetic Nervous System / Q000187:drug effects / Q000502:physiology*; D014520:Urethane; D014628:Vagotomy; D014630:Vagus Nerve / Q000502:physiology
D014520:Urethane; D011343:Procaine; D009020:Morphine; D001285:Atropine; D011433:Propranolol; D010424:Pentobarbital
Uchastie simpaticheskoĭ innervatsii serdtsa v vozniknovenii vagotomicheskoĭ i atropinovoĭ takhikardii u narkotizirovannykh sobak