title: [Quantitative determination of tissue tolerance to corrosion products in organ culture].
abstract: The tissue tolerance for metal was investigated using an organ culture of embryonic rat femora. We found reproducible results using a standardized experimental method. A good correlation between the applied concentrations and resulting growth inhibition occurred and dose-response curves were established. The experimental model is applicable for testing tissue  tolerance for the soluble products.
mesh_terms: D000818:Animals; D001846:Bone Development / Q000187:drug effects; D002712:Chlorides / Q000494:pharmacology; D003343:Corrosion; D004361:Drug Tolerance; D005269:Femur / Q000187:drug effects* / Q000254:growth & development; D008670:Metals / Q000494:pharmacology*; D009924:Organ Culture Techniques; D051381:Rats
chemical_list: D002712:Chlorides; D008670:Metals
vernacular_title: Quantitative Bestimmung der Gewebsverträglichkeit von Korrosionsprodukten in der Organkultur