The influence of sodium on the electrical and mechanical activity of the ureter.
In Sodium-deficient solutions both the electrical and mechanical activity of the ureter are reduced. The plateau component of the action potential in the smooth muscle cell of the guinea pig ureter is more affected than the oscillations. Tetrodotoxin, which blocks the action potential in nerves, does not influence activity or conduction in the ureter. This is an important argument for the myogenic conduction of activity in this tissue.
D000200:Action Potentials / Q000187:drug effects*; D000818:Animals; D005260:Female; D006168:Guinea Pigs; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects*; D012964:Sodium / Q000494:pharmacology*; D012965:Sodium Chloride / Q000494:pharmacology; D013779:Tetrodotoxin / Q000494:pharmacology; D014513:Ureter / Q000187:drug effects*
D013779:Tetrodotoxin; D012965:Sodium Chloride; D012964:Sodium