title: [Treatment of hypertension with propranolol in combination with other antihypertensive agents].
abstract: In two separated treatment groups of 18 and 30 hypertensive patients of the clinical degrees of severity II and III after insufficient propranolol monotherapy a combined propranolol/hydralazine or propranolol/hydrochlorothiazide treatment, respectively, was performed during several months. Under the combination therapy on average a clear increase of the effect of the beta-receptor blocker on the systolic as well as on the diastolic blood pressure is achieved. There were no essential side-effects. In accordance with modern opinions in the therapy of hypertension the combination of propranolol with a peripheral vasodilator and/or a salidiuretic should find a wide area of use, above all in hypertensive patients who are diastolically more difficult to be stabilised. The production of an adequate combination preparation is to be taken into consideration.
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006830:Hydralazine / Q000627:therapeutic use; D006852:Hydrochlorothiazide / Q000627:therapeutic use; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011433:Propranolol / Q000008:administration & dosage* / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000959:Antihypertensive Agents; D014665:Vasodilator Agents; D006852:Hydrochlorothiazide; D006830:Hydralazine; D011433:Propranolol
vernacular_title: Hochdruckbehandlung mit Propranolol in Kombination mit anderen Antihypertensiva