[Antibiotic sensitivity of S. typhi cultures that have reverted from L forms isolated from the blood of patients].
L-forms of bacteria were isolated in 18 out of 300 fever patients with diagnoses of typhoid-paratyphoid fever, grippe, virus respiration disease and others in the Diagnostic Department of an Infection Hospital during bacteriological tests of the blood. Among the cultures tested 13 were instable and reversed to the bacterial form. The type identification showed that only 9 revertants possessed properties characteristic of the typhoid fever microbes and belonged to S. typhi. Sensitivity of the typhoid fever revertants to levomycetin, sintomycin, streptomycin, pencillin and tetracycline was studied. The studies showed that the typhoid fever revertants from the L-forms isolated from the patients were sufficiently sensitive to levomycetin, sintomycin, penicillin and tetracycline. The minimum bactericidal concentrations of the above antibiotics ranged within 12.5--100 gamma/ml.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001769:Blood / Q000382:microbiology*; D002701:Chloramphenicol / Q000494:pharmacology; D006801:Humans; D007740:L Forms / Q000187:drug effects* / Q000201:enzymology; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000494:pharmacology; D012485:Salmonella typhi / Q000187:drug effects* / Q000201:enzymology; D013307:Streptomycin / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D010406:Penicillins; D002701:Chloramphenicol; D013752:Tetracycline; D013307:Streptomycin
Chuvstvitel'nost' k antibiotikam kul'tur S. typhi, reversirovavshikh iz L-form, vydelennykh iz krovi bol'nykh