[Migration of glial cells in the brains of intact mice and mice with brain injuries during the first hours after DNA synthesis and cell division].
The behaviour of labelled (3H-thymidine) glial cells was studied in the brain of intact mice and mice with mechanical trauma of brain. Formation of pairs of labelled cells and their subsequent disjunction in the brain regions under study occurs at different rates. The rates of these processes in white matter and subependymal zone exceed those in parietal cortex, thalamus and hypothalamus. The brain traumatization does not influence the rate of disjunction of separated glial cells. Angles between axes of separated cells are different in the brain regions under study. In cortex and white matter, separated cells with axial angles equal to 180 degrees predominate whereas in thalamus, hypothalamus and subependymal zone many separated cells have axial angles below 180 degrees (120-160 degrees). The possible relationship between the form of the brain regions under study and the value of axial angles of separated cells is discussed.
D000818:Animals; D001930:Brain Injuries / Q000503:physiopathology*; D002455:Cell Division; D002465:Cell Movement; D002540:Cerebral Cortex / Q000503:physiopathology; D004247:DNA / Q000096:biosynthesis*; D007031:Hypothalamus / Q000503:physiopathology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D008815:Mice, Inbred Strains; D009457:Neuroglia; D013788:Thalamus / Q000503:physiopathology; D013936:Thymidine / Q000378:metabolism
D004247:DNA; D013936:Thymidine
Osobennosti peremeshcheniia glial'nykh kletok mozga intaktnykh mysheĭ i mysheĭ s travmoĭ mozga v pervye chasy posle sinteza DNK i kletochnogo deleniia