Herediatary anhidrotic ectodermal dysplasia. Studies in a Nigerian famil.
Studies in a Nigerian family with hereditary anhidrous ectodermal dysplasia are reported. Microscopical examinations of finger tips for sweat pores were diagnostic in phenotypes, and it is suggested that this simple nonsurgical procedure is a preferred alternative to skin biopsies in the diagnosis of the syndrome. The clinical implications of a tropical environment for the syndrome, as well as the factors that may favour maintenance of the gene in such an environment are discussed.
D000848:Anodontia; D044383:Black People; D002648:Child; D002675:Child, Preschool; D004476:Ectodermal Dysplasia / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D005260:Female; D005334:Fever / Q000150:complications; D005838:Genotype; D006197:Hair / Q000002:abnormalities; D006358:Hot Temperature / Q000009:adverse effects; D006801:Humans; D007007:Hypohidrosis / Q000235:genetics*; D007223:Infant; D008297:Male; D009549:Nigeria; D010862:Pilocarpine; D012867:Skin / Q000473:pathology; D013545:Sweat Glands / Q000002:abnormalities / Q000378:metabolism; D013546:Sweating / Q000187:drug effects; D014071:Tooth Abnormalities
D010862:Pilocarpine