title: Contact urticaria from cobalt chloride.
abstract: Cobalt chloride should be added to the ever growing list of contact urticants. This chemical is frequently used as a color indicator in provocative sweat testing. In this case, contact urticaria was probably nonimmunologic in origin. Since diphenhydramine and 48-80 (polymonine block this reaction to cobalt chloride, vasoactive amines are at least partially responsible for the urticaria.
mesh_terms: D000433:1-Propanol; D000328:Adult; D002648:Child; D003035:Cobalt / Q000009:adverse effects*; D004155:Diphenhydramine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D014677:Pharmaceutical Vehicles; D013542:Sweat; D014581:Urticaria / Q000139:chemically induced* / Q000517:prevention & control; D003189:p-Methoxy-N-methylphenethylamine / Q000627:therapeutic use
chemical_list: D014677:Pharmaceutical Vehicles; D003035:Cobalt; D003189:p-Methoxy-N-methylphenethylamine; D004155:Diphenhydramine; D000433:1-Propanol