title: The concentration of testosterone in serial samples  of peripheral venous plasma from infertile women.
abstract: The concentration of testosterone has been determined in daily samples of peripheral venous plasma throughout one complete menstrual cycle from each of 4 women with regular, but anovulatory cycles (Group 1) and 13 apparently normal, but infertile women (Group 2). The individual patterns and combined values have been compared with those obtained from 9 healthy volunteers (Group 3), who appeared to satisfy strict criteria for normal ovarian and uterine function. The menstrual cycles from subjects in groups 2 and 3 were subdivided retrospectively into follicular, periovulatory and luteal phases according to the day of the LH peak. The results show that the values for every subject in Group 1 tended to remain relatively costant and the overall concentration (32.3 +/- 10.4; ng/100ml; mean +/- SD) was significantly lower (P less than 0,05, student's "t" test) than the corresponding figure for Group 3 (41.6 +/- 11.8). The patterns of testosterone in Groups 2 and 3 were variable, but the overall concentrations in Group 2 during the periovulatory phase (53.7 +/- 12.7) was significantly higher (P less than 0.025) than the corresponding value (41.9 +/- 11.9) for Group 3. The findings are discussed.
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D000858:Anovulation; D003097:Collateral Circulation; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000097:blood* / Q000209:etiology; D007986:Luteinizing Hormone / Q000097:blood; D008598:Menstruation; D010060:Ovulation; D011374:Progesterone / Q000097:blood; D013739:Testosterone / Q000097:blood*; D014680:Veins
chemical_list: D013739:Testosterone; D011374:Progesterone; D007986:Luteinizing Hormone