Some toxic, physical and chemical properties of the oral secretion of the sand tampan, Ornithodoros savignyl Audouin (1827).
Mice, exposed to the effects of the oral secretion of Ornithodorus savignyi by injection, revealed that a potent toxin is present in the secretion. Electrophoretic and chromatographic separations of the secretion showed a heterogeneous pattern of protein-like substances. Toxicity trials on these fractions showed that the toxic principle is protein in nature and fairly heat stable.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002854:Chromatography, Paper; D002855:Chromatography, Thin Layer; D004586:Electrophoresis; D005260:Female; D007928:Lethal Dose 50; D051379:Mice; D009584:Nitrogen / Q000032:analysis; D011506:Proteins / Q000032:analysis; D013056:Spectrophotometry, Ultraviolet; D013987:Ticks / Q000032:analysis*; D014118:Toxins, Biological / Q000032:analysis* / Q000633:toxicity
D000596:Amino Acids; D011506:Proteins; D014118:Toxins, Biological; D009584:Nitrogen