Serum enzyme levels in anaesthetic personnel.
The reported studies were carried out on 22 persons, 15 anaesthetists and 7 anaesthetic nurses with a history of long-term exposure to halothane in low concentrations. The activity of gamma-glutamyl-transpeptidase (GGTP) and aminotransferases, the level of bilirubin and thymol turbidity test were determined. No significant abnormalities were found in the mean values of these determinations. In some cases a rise in alkaline phosphatase activity and in two cases a rise of GGTP were found. The results are not suggesting the presence of hepatocellular damage in this group.
D000328:Adult; D000368:Aged; D000776:Anesthesiology; D056486:Chemical and Drug Induced Liver Injury; D005260:Female; D006221:Halothane / Q000506:poisoning*; D006801:Humans; D008099:Liver / Q000187:drug effects*; D008107:Liver Diseases / Q000175:diagnosis; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis; D010458:Peptidyl Transferases / Q000097:blood; D000637:Transaminases / Q000097:blood; D014166:Transferases / Q000097:blood*; D000078329:Workforce
D014166:Transferases; D010458:Peptidyl Transferases; D000637:Transaminases; D006221:Halothane