title: [Chronic primary intrahepatic cholestasis. Anatomo-clinical study of 11 cases].
abstract: An anatomoclinical study is carried out in 11 cases of apparently primary intrahepatic cholestasis. Two groups have been distinguished: one includes three cases with poorly specific and disparate changes. Contrarely, the other group, including eigh cases, shows quite evocative and stereo-typed histological lesions. These are alwayst epithelial and segmental canalar lesions with characteristic cellular infiltrations of variable occurrence and location. The lesions develop into multilating sclerosis with progressive loss of the florid lesions. This group may be assimilated to the affection commonly known as Hanot and Mac Mahon's disease. Antimitochondria antibodies are very often found in this anatomoclinical entity but their absence does not allow exclusion of the diagnosis. Nevertheless, anatomical, clinical and biological correlation remains indispensable.
mesh_terms: D000328:Adult; D000368:Aged; D001653:Bile Ducts, Intrahepatic / Q000473:pathology*; D002779:Cholestasis / Q000473:pathology*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000473:pathology*; D008875:Middle Aged
vernacular_title: Les cholestases intra-hépatiques chroniques primitives. Etude anatomo-clinique de 11 observations