The effect of enhancing factor on the immunity of mice against tetanus.
Enhancing factor was prepared from spleens of mice primed and reinjected with tetanus toxoid. The culture supernatant was separated by gel chromatography on Sephadex G-150, the resulted fractions were ultrafiltered and their enhancing activity was tested in vivo. The 1st fraction separated by gel chromatography proved to be active.
D000818:Animals; D005591:Chemical Fractionation; D002850:Chromatography, Gel; D007109:Immunity; D051379:Mice; D013154:Spleen / Q000276:immunology; D013742:Tetanus / Q000276:immunology* / Q000401:mortality; D013745:Tetanus Toxoid / Q000494:pharmacology
D013745:Tetanus Toxoid