Dydrogesterone and endometriosis.
The results are reported of the administration of dydrogesterone, 5 mg twice daily, to 49 patients with endometriosis. All but five patients were symptom-free after nine months of therapy. Most subjective symptoms had disappeared within four to eight weeks; dyspareunia usually took longer. In 30 out of 32 patients who had a culdoscopy after one or two treatment courses, a 'cure' of endometriosis was confirmed. Ten out of nineteen infertile patients became pregnant following treatment. The only side-effects were transient mastalgia and dizziness in two patients. No amenorrhoea or other disturbances of the menstrual cycle were reported.
D000328:Adult; D003464:Culdoscopy; D004394:Dydrogesterone / Q000627:therapeutic use*; D004715:Endometriosis / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000188:drug therapy*
D004394:Dydrogesterone