In vivo measurement of 32P in the brain of a freely moving rat.
A new method for measuring the uptake of materials labeled with radioactive phosphorus (32P) in the brain of a freely moving rat is described. The rate of uptake in the brain of a single animal of 32P-labeled phosphate was compared to the uptake rate in the animal's blood or liver. A comparison was made between the uptake following an intravenous (IV) or an intraperitoneal (IP) injection. The effect of convulsions caused by injections of metrazol on the kinetics of 32P uptake in the brain is described.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D007274:Injections, Intraperitoneal; D007275:Injections, Intravenous; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D008297:Male; D010433:Pentylenetetrazole; D010758:Phosphorus / Q000378:metabolism*; D010761:Phosphorus Radioisotopes; D051381:Rats; D012588:Scintillation Counting; D012640:Seizures / Q000139:chemically induced / Q000378:metabolism
D010761:Phosphorus Radioisotopes; D010758:Phosphorus; D010433:Pentylenetetrazole