[Change in the activity of glycolytic enzymes in different areas of the albino rat brain in dependence on the stress agent].
The activity of aldolase, lactate dehydrogenase and its isoenzymes was studied in various areas of the albino rat brain in stressed state connected with insomnia and fatigue. The activity of the mentioned enzymes in the brain various areas is established to change differently and depend on the stress agent. So, under insomnia the activity of aldolase increases in the horn of Ammon and midbrain and that of lactate dehydrogenase--in the great hemispheres and cerebellum. Under conditions of fatigue the activity of aldolase does not change, that of lactate dehydrogenase lowers in the great hemispheres and stem. In fatigue the activity of isoenzyme LDG1 lowers and that of LDG4+5--increases in the great hemispheres, stem and cerebellum. The activity of these isoenzymes is unchanged with insomnia.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D001933:Brain Stem / Q000201:enzymology; D002531:Cerebellum / Q000201:enzymology; D005221:Fatigue / Q000201:enzymology; D005634:Fructose-Bisphosphate Aldolase / Q000378:metabolism; D006019:Glycolysis; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008636:Mesencephalon / Q000201:enzymology; D009928:Organ Specificity; D051381:Rats; D007319:Sleep Initiation and Maintenance Disorders / Q000201:enzymology; D013312:Stress, Physiological / Q000201:enzymology*
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D005634:Fructose-Bisphosphate Aldolase
Izmenenie aktivnosti fermentov glikoliza v razlichnykh otdelakh mozga krys v zavisimosti ot stressornogo agenta