[Post-transfusional hepatitis as a complication of surgery using the heart-lung-machine in childhood].
After open-heart surgery with extracorporeal circulation on 41 children with congenital heart disease in 13 (about 32%) a hepatitis with a long incubation period developed. In 6 out of 13 children (46%) HBS-Ag and in 2 additional ones anti-HBS could be detected. In 6 of 13 cases (46%) a chronic hepatitis ensued, which could be proved histologically in 4 cases.
D000293:Adolescent; D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001798:Blood Proteins / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000601:surgery; D006355:Heart-Lung Machine; D006505:Hepatitis / Q000209:etiology; D006509:Hepatitis B / Q000209:etiology*; D006511:Hepatitis B Antigens / Q000032:analysis; D006801:Humans; D007223:Infant; D008297:Male; D013997:Time Factors; D065227:Transfusion Reaction
D001798:Blood Proteins; D006511:Hepatitis B Antigens; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D001663:Bilirubin
Die posttransfusionelle Hepatitis als Komplikation nach Operationen mit Hilfe der Herz-Lungen-Maschinen im Kindesalter