The release of glutamic acid from isolated brain tissues.
The glutamic acid and other primary amines released spontaneously and by electrical pulses from rat brain caudate and cortex were measured by the fluorescamine method. Electrical pulses evoked a transient release of glutamic acid which was greater from caudate tissue. Both morphine and reserpine, in vivo, inhibited the spontaneous glutamic acid release but not the loss of glutamic acid due to pulses.
D000818:Animals; D002421:Caudate Nucleus / Q000187:drug effects / Q000378:metabolism* / Q000502:physiology; D002540:Cerebral Cortex / Q000187:drug effects / Q000378:metabolism* / Q000502:physiology; D004558:Electric Stimulation; D005971:Glutamates / Q000378:metabolism*; D066298:In Vitro Techniques; D009020:Morphine / Q000494:pharmacology; D051381:Rats; D012110:Reserpine / Q000494:pharmacology; D013997:Time Factors
D005971:Glutamates; D009020:Morphine; D012110:Reserpine