Treatment of melasma (chloasma) by local application of a steroid cream.
15 patients with melasma were treated with betamethasone 17-valerate in a cream base containing DMSO. One patient with secondary pigmentation was also entered in the trial. In nine patients results were favourable and in three results were moderate. This effect could be ascribed to the steroid.
D000287:Administration, Topical; D000328:Adult; D001623:Betamethasone / Q000031:analogs & derivatives*; D001624:Betamethasone Valerate / Q000008:administration & dosage / Q000627:therapeutic use*; D004121:Dimethyl Sulfoxide; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D010859:Pigmentation Disorders / Q000188:drug therapy*
D001623:Betamethasone; D001624:Betamethasone Valerate; D004121:Dimethyl Sulfoxide