title: Adrenocortical function: corticosterone levels in female BALB/c and C3H mice under various conditions.
abstract: A diurnal rhythmicity in plasma corticosterone levels was demonstrated in female BALB/cCrgl and C3H/Crgl mice, with and without mammary tumor virus. Removal of the adrenals followed by metopirone treatment reduced circulating corticoid to non-detectable levels in C3H but not in BALB/c mice. Dexamethasone strains. Neonatal exposure to exogenous hormones failed to cause any obvious change in corticoid levels. Bilateral ovariectomy of these neonatally treated mice at 40 days of age resulted in a subsequent lowering of plasma corticoid levels when compared with intact animals.
mesh_terms: D000302:Adrenal Cortex / Q000187:drug effects / Q000378:metabolism*; D000311:Adrenal Glands / Q000378:metabolism*; D000315:Adrenalectomy; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology; D002369:Castration; D002940:Circadian Rhythm; D003345:Corticosterone / Q000097:blood*; D003907:Dexamethasone / Q000494:pharmacology; D005260:Female; D008797:Metyrapone / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C / Q000502:physiology*; D008809:Mice, Inbred C3H / Q000502:physiology*
chemical_list: D003907:Dexamethasone; D003345:Corticosterone; D008797:Metyrapone