title: Canine hepatitis virus infections in dogs of São Paulo city, Brazil.
abstract: Infectious Canine Hepatitis virus was isolated from 10 of 51 tested dogs caught in São Paulo and neighbouring Districts. The viruses were isolated in dog kidney cell cultures from fecal specimens and, in two instances, from the non-inoculated cell cultures themselves. All the isolated virus strains presented biological and physicochemical characteristics proper to the adenovirus and were immunologically identified as ICH virus. Specific neutralizing antibodies to the ICH virus were found in 50% of the dogs with negative virus isolations in titers from 1/500 to 1/25,000. These results point to a very high frequency of infection by the ICH virus in the sample studied.
mesh_terms: D000818:Animals; D001938:Brazil; D004283:Dog Diseases / Q000453:epidemiology* / Q000382:microbiology; D004285:Dogs; D006518:Hepatitis Viruses / Q000302:isolation & purification*; D006524:Hepatitis, Viral, Animal / Q000453:epidemiology* / Q000382:microbiology