[Experimental analysis of the effects of the psychostimulant sydnocarb].
Used in a dose of 2-15 mg/kg in dogs and in a dose of 2-40 mg/kg in rabbits sydnocarb produced a stimulating effect, this being born out by conditioned reflex, electrographic and behavioral tests. Already the next day following introduction of the drug this effect in tests with dogs gave place to an inhibitory action. Introduction of the agent in all of the study does exerted a certain influence on the heart rate. At the earliest the electrographic effects were recorded in the cortical structures of the rabbit's brain, but proved most intensive in the limbic structures, when the dosage of the drug was increased up to 15-40 mg/kg.
D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects; D003214:Conditioning, Classical / Q000187:drug effects; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D004594:Electrophysiology; D004924:Escape Reaction / Q000187:drug effects; D005750:Gastric Juice / Q000378:metabolism; D006339:Heart Rate / Q000187:drug effects; D007097:Imines / Q000494:pharmacology; D010069:Oxadiazoles / Q000494:pharmacology*; D011817:Rabbits; D011930:Reaction Time / Q000187:drug effects; D013558:Sydnones / Q000494:pharmacology*
D000928:Antidepressive Agents; D007097:Imines; D010069:Oxadiazoles; D013558:Sydnones
Eksperimental'nyĭ analiz éffektov psikhostimuliatora sidnokarba