[Effect of an anabolic steroid (methenolone enanthate) on the intra- and extravasal albumin pool in liver cirrhosis].
15 patients with a histologically and/or peritoneoscopically proven cirrhosis of the liver were treated for four weeks with 200 mg metenolonenanthate (Depot-Primobolan) per week. Before and after the treatment the intravascular and extravascular pool and daily turnover of albumin were measured with 125J-albumin. All patients had a well "compensated" cirrhosis. The only significant difference between the values of the cirrhotic patients and those of a control group of patients was a reduction of the albumin turn-over. The anabolic steroid enlarged the turn-over, the effect was the more pronounced the more pronounced the more the turn over was diminished before the treatment.
D000328:Adult; D000368:Aged; D001808:Blood Vessels / Q000378:metabolism; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000188:drug therapy / Q000378:metabolism*; D008297:Male; D008710:Methenolone / Q000008:administration & dosage* / Q000627:therapeutic use; D008875:Middle Aged; D012709:Serum Albumin / Q000378:metabolism*; D012711:Serum Albumin, Radio-Iodinated; D013997:Time Factors
D012709:Serum Albumin; D012711:Serum Albumin, Radio-Iodinated; D008710:Methenolone
Die Wirkung eines anabol wirkenden Steroids (Metenolonönanthat) auf den intra- und extravasalen Albuminpool bei Leberzirrhose