[Effect of acute cold exposure on blood composition in rats treated with 6-Hydroxydopamine (author's transl)].
Rats injected with 6-hydroxydopamine (6-OHDA) into the lateral ventricle showed greater elevation in plasma FFA and beta-hydroxybutyrate and significant decrease in blood sugar and lactate following acute cold exposure at -10 degrees C for 2 hours. Changes in the blood composition induced by the cold exposure in rats treated with 6-OHDA intravenously were not different from those observed in control rats. Adrenomedullectomized rats treated with 6-OHDA responded to the cold exposure with rather marked elevation in plasma FFA and beta-hydroxybutyrate. These results were discussed from the view-point of compensatory changes in metabolic regulation in the absence of norepinephrine.
D000313:Adrenal Medulla / Q000187:drug effects; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003080:Cold Temperature; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006885:Hydroxybutyrates / Q000378:metabolism; D006892:Hydroxydopamines / Q000008:administration & dosage / Q000494:pharmacology*; D007773:Lactates / Q000097:blood; D008297:Male; D010812:Physical Stimulation; D051381:Rats
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D006885:Hydroxybutyrates; D006892:Hydroxydopamines; D007773:Lactates