title: Glomerular lesions and final outcome in children with glomerulonephritis of acute onset.
abstract: 131 children with nephritic syndrome of acute onset were studied by renal biopsy and were followed clinically from 2 to 13 years.  87 patients (66%) with proliferative endocapillary glomerulonephritis all recovered. 21 (16%) had focal extracapillary and diffuse endocapillary glomerulonephritis. Eleven (52%) of these recovered. Six patients (5%) had diffuse extra and endocapillary glomerulonephritis, 13 (10%) had membrano-proliferative glomerulonephritis and four had diffuse glomerular fibrosis. All 23 patients of the latter groups progressed to renal insufficiency. A correlation between morphology and prognosis was apparent in this study.
mesh_terms: D000208:Acute Disease; D002196:Capillaries / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003165:Complement System Proteins / Q000378:metabolism; D005921:Glomerulonephritis / Q000175:diagnosis / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007678:Kidney Glomerulus / Q000098:blood supply; D009404:Nephrotic Syndrome / Q000473:pathology; D011379:Prognosis; D013290:Streptococcal Infections
chemical_list: D003165:Complement System Proteins