[Stimulation of cellular immunity and immunologic memory be somatotropic hormone].
The role of somatotropic hormone (STH) in the development of delayed hypersensitivity and immunological memory was studied in guinea pigs. The STH injected at periods of sensitization and realization of delayed hypersensitivity stimulated the skin reactions. Suppression of the endogenic STH by the antiserum to the guinea pig. STH prevented development of hypersensitivity at both periods. Hypersensitivity was restored after the cessation of antiserum effects. The period of sensitization proved to be most sensitive, whereas the period of immunological memory persistence remained resistant.
D000818:Animals; D005260:Female; D013006:Growth Hormone / Q000494:pharmacology* / Q000627:therapeutic use; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed / Q000188:drug therapy* / Q000517:prevention & control; D007111:Immunity, Cellular / Q000187:drug effects*; D007156:Immunologic Memory / Q000187:drug effects*
D013006:Growth Hormone
Stimuliatsiia somatotropnym gormonom kletochnogo immuniteta i immunologicheskoĭ pamiati