[Diuretics on the basis of N-substituted 2,4-diamino-s-triazines by cyclisation of biguanides (author's transl)].
The structural class of 2,4-diamino-s-triazines (5) functioning as diuretics has become accessible by a novel preparatory procedure. The new synthesis is based on the aminomethinylating principle of s-triazine (1), under the action of which biguanides (2) are cyclized to 5 passing through the intermediary states 3 and 4.
D001645:Biguanides; D003500:Cyclization; D003959:Diamines / Q000138:chemical synthesis; D004232:Diuretics / Q000138:chemical synthesis*; D014227:Triazines / Q000138:chemical synthesis*
D001645:Biguanides; D003959:Diamines; D004232:Diuretics; D014227:Triazines
Diuretika auf der Grundlage N-substituierter 2,4-Diamino-s-triazine durch Zyklisierung von Biguaniden