title: On the evocability of a positive oestrogen feedback action on LH secretion in transsexual men and women.
abstract: In transsexual men with homosexual behaviour and intact testicular function, as well as in homosexual men with normal gender identity, following a negative oestrogen feedback effect a delayed positive oestrogen feedback action on LH secretion was evoked. By contrast, in transsexual men with hypo- or asexuality and intact testes or hypergonadotrophic hypo- or agonadism, as well as in heterosexual men with normal gender identity, a negative oestrogen feedback effect was not followed by a positive feedback action on LH release. In transsexual women with homosexual behaviour and oligo- and/or hypomenorrhoea, only a weak or at best moderate positive oestrogen feedback action on LH release was evocable, similarly as in castrated and oestrogen-primed heterosexual men. By contrast, in a transsexual woman with bisexual behaviour and eumenorrhoea, a strong positive oestrogen feedback action on LH secretion was evocable, as well as in heterosexual women with normal gender identity.
mesh_terms: D001921:Brain / Q000254:growth & development; D004967:Estrogens / Q000494:pharmacology*; D005246:Feedback; D005260:Female; D006801:Humans; D007986:Luteinizing Hormone / Q000378:metabolism*; D008297:Male; D012741:Sexual Maturation; D014189:Transsexualism / Q000378:metabolism*
chemical_list: D004967:Estrogens; D007986:Luteinizing Hormone