[The reaction of the cardio-circulatory system during the introduction of the modificated NLA (AUTHOR'S TRANSL)].
The hemodynamic effects of Etomidate are examined during the introduction of a modificated NLA. The following parameters are registrated: Heart Rate, Arterial and Mean Arterial Pressure, Pulmonary and Mean Pulmonary Pressure, and Cardiac Output. The Total Periphere Resistance and the Tension-Time-Index are calculated. Apart from a short moment during and immediately after intubation a remarkable constancy of all parameters is found. The alpha-receptor-blocking effect of Etomidate and DHB and the resulting decrease of the Total-Periphere Resistance are compensated by infusion of a colloidsolution. Myoclonias are not observed. Etomidate may be regarded as a drug with few effects on the circulation. It may be thinkable, that by means of Etomidate even in shock a careful introduction is possible.
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects*; D004341:Drug Evaluation; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008875:Middle Aged; D009458:Neuroleptanalgesia; D011229:Preanesthetic Medication
Das Verhalten des kardiozirkulatorischen Systems bei einer modifizierten NLA-Einleitung mit Etomidate. Eine klinisch experimentelle Studie