title: Cerebral blood flow in patients with intracranial pressure elevation due to traumatic brain edema.
abstract: The object of this study was to determine if traumatic brain edema (BE) and increased intracranial pressure (ICP) reduce cerebral blood flow (CBF). Two groups of patients were studied, one with slight BE and ICP less than 20 mm Hg., the other with pronounced BE and ICP over 20 mm Hg. Although ICP was higher and cerebral perfusion pressure lower in pronounced edema there was only a small and non-significant reduction in CBF and no difference in cerebro-vascular resistance. Since traumatic BE does not increase resistance to blood flow through the brain, cerebral perfusion can be maintained if an adequate perfusion pressure is established. This in turn, demands the monitoring and control of ICP.
mesh_terms: D001794:Blood Pressure; D001929:Brain Edema / Q000209:etiology / Q000503:physiopathology*; D001930:Brain Injuries / Q000209:etiology / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D006801:Humans; D007427:Intracranial Pressure; D010477:Perfusion; D014655:Vascular Resistance