title: Ganglioside and rabbit erythrocyte membrane receptor for staphylococcal alpha-toxin.
abstract: The hemolytic activity of staphylococcal alpha-toxin is inhibited by an N-acetylglucosamine-containing ganglioside (GlcNAc-ganglioside) but not by any of the related glycolipids. The GlcNAc-ganglioside also is precipitated with the toxin by a gel-diffusion technique. It is postulated that GlcNAc-ganglioside may be the membrane receptor for the alpha-toxin.
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000502:physiology; D004912:Erythrocytes; D005732:Gangliosides / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects; D011817:Rabbits; D011955:Receptors, Drug / Q000187:drug effects*; D013210:Staphylococcus; D014118:Toxins, Biological / Q000378:metabolism*
chemical_list: D005732:Gangliosides; D011955:Receptors, Drug; D014118:Toxins, Biological