Effects of insulin hypoglycaemia in the sheep on jugular haematocrit and plasma corticosteroid concentrations.
Insulin hypoglycaemia, by acting as a stressor, caused an increase in plasma corticosteroid concentration in sheep. It did not increase jugular haematocrit in splenectomized sheep, but caused an increase, presumably by splenic contraction, in the following sheep: two control, one with one adrenal cortex as its only adrenal tissue, two with denervated spleens, and two splanchnicotomized animals. These preparations showed that insulin hypoglycaemia can cause a splenic contraction in the absence of an increase in plasma adrenaline and after splenic extrinsic denervation.
D000305:Adrenal Cortex Hormones / Q000097:blood*; D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D003714:Denervation; D006400:Hematocrit; D007328:Insulin / Q000494:pharmacology*; D007601:Jugular Veins; D008297:Male; D012756:Sheep; D013153:Splanchnic Nerves / Q000502:physiology; D013154:Spleen / Q000294:innervation / Q000502:physiology; D013156:Splenectomy; D013268:Stimulation, Chemical
D000305:Adrenal Cortex Hormones; D001786:Blood Glucose; D007328:Insulin