Guanidine inhibits tobacco mosaic virus RNA synthesis at two stages.
Guanidine (GD) inhibited tobacco mosaic virus (TMV) RNA synthesis at two different steps, depending on the concentration of GD used. The time-course of inhibition by 40 mM GD coincided with the time-course of RNA synthesis. However, 10 mM GD inhibited an earlier step that occurred prior to viral RNA synthesis.
D003864:Depression, Chemical; D006146:Guanidines / Q000494:pharmacology*; D010947:Plants, Toxic; D012367:RNA, Viral / Q000096:biosynthesis*; D013997:Time Factors; D014026:Nicotiana / Q000382:microbiology; D014027:Tobacco Mosaic Virus / Q000254:growth & development / Q000378:metabolism*; D014779:Virus Replication / Q000187:drug effects
D006146:Guanidines; D012367:RNA, Viral