[The electrical structure of normal liver tissue].
The electrical coupling between cells of mouse liver was investigated in vitro. The membrane potential of liver cells is 15--30 mv immediatly after dissection, and increases to 40--48 mv within 4--7 hours. This level of membrane potential is constant during the next 2--3 hours. The mean input resistance varies within 189+/-9 and 613+/-+25 kohm to be higher in preparations examined in summer than in winter time. The cytoplasm of liver cells is equipotential. The reducing of potential from intracellular source is not exponential. This potential distribution is well approximated by a solution for the two-dimentional model of the liver lamella, when characteristic length is 500 mcm. On the basis of this model the outher membrane resistance and functional membrane resistance were found to be 700-2100 and 1.2 ohm-cm2, resp.
D000818:Animals; D004594:Electrophysiology; D006221:Halothane / Q000494:pharmacology; D066298:In Vitro Techniques; D008099:Liver / Q000502:physiology*; D008297:Male; D008564:Membrane Potentials; D051379:Mice
D006221:Halothane
Elektricheskaia struktura tkani normal'noĭ pecheni