[Verrucous mycotic dermatitis due to an unusual dematiaceous fungus. Clinical and histopathological discussion (author's transl)].
A case of "verrucous dermatitis" caused by a dematiaceous fungus has been observed in an 30 y. o. Algerian patient. The lesion was localized on the face. The patient presented previously a chronic dermatophytic disease due to Trichophyton verrucosum. The dematiaceous hyphomycete has been isolated several time from superficial specimens and portions of biopsies. This fungus has been injected by intra-testicular route in guinea-pigs. The aspect of the fungus in its parasitical morphology has been described and compared with that seen in the testis: In the lesions, the vesiculous or short fungal elements are not pigmented; they are sometimes cross-walled. Successful treatment has been obtained with administration of intravenous amphotericin B. It seems that the patient is genetically predisposed and has a deficient cellular mediated immunity.
D000328:Adult; D000462:Algeria; D000666:Amphotericin B / Q000627:therapeutic use; D000818:Animals; D003881:Dermatomycoses; D005658:Fungi / Q000145:classification / Q000302:isolation & purification; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000382:microbiology; D009262:Nails / Q000382:microbiology; D014005:Tinea / Q000150:complications
D000666:Amphotericin B
Dermatite verruqueuse mycosique due a un champignon dématié inhabituel. Discussion clinique et histopathologique