Immunoreactive calcitonin production by human lung carcinoma cells in culture.
Monolayer cultures have been established from a poorly differentiated carcinoma of the lung. Homogeneous cell growth and morphology have been maintained for over 18 months through more than 80 subculture passages, and the cells have been found to produce both immunoreactive calcitonin and an immunoreactive carcinoembryonic antigen-like material.
D000368:Aged; D002116:Calcitonin / Q000096:biosynthesis* / Q000276:immunology; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002478:Cells, Cultured; D006729:Hormones, Ectopic / Q000096:biosynthesis*; D006801:Humans; D008175:Lung Neoplasms / Q000276:immunology / Q000378:metabolism* / Q000648:ultrastructure; D008297:Male
D002272:Carcinoembryonic Antigen; D006729:Hormones, Ectopic; D002116:Calcitonin