Determination of the glycogen contents in the brains of perinatal and newborn rabbits under conditions of experimental hypoxia.
The glycogen contents of 121 rabbit brains having different levels of hypoxia were determined, calculation being in mg% of glucose per g of brain. It was possible to observe significant reductions in carbohydrate content under conditions of acute and chronic hypoxia. Moderate prepartum accumulation of glycogen in untreated rabbit brains is likely. Chronic reduction in reserve fuel resulted in deficient development of the brain, as is clearly shown by brain weight determinations. This enables a parallel between this condition and intrauterine dystrophia.
D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000254:growth & development / Q000378:metabolism*; D004195:Disease Models, Animal; D005260:Female; D005311:Fetal Hypoxia / Q000378:metabolism*; D006003:Glycogen / Q000378:metabolism*; D000860:Hypoxia / Q000378:metabolism; D009929:Organ Size; D011247:Pregnancy; D011817:Rabbits
D006003:Glycogen