[Morphofunctional manifestations of rat adrenal cortical reaction to the administration of sodium bromide under conditions of hypodynamic stress].
Experiments conducted on rats by employing functional and morphological methods of investigation showed bromine to weaken the function of the adrenal cortex in intach rats, producing changes analogous to those of a hypodynamic stress (2-hour immobilization on the operating table). A combined preliminary introduction of bromine and immobilization is attended by a less pronounced stress reaction and brings about normalization of the ascorbic acid content in the adrenals with the appearance of well-marked morphological signs pointing to the compensation of the adrenal cortex functions.
D000302:Adrenal Cortex / Q000187:drug effects* / Q000503:physiopathology; D000311:Adrenal Glands / Q000187:drug effects* / Q000378:metabolism; D000309:Adrenal Insufficiency / Q000503:physiopathology; D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism; D001965:Bromides / Q000494:pharmacology*; D002784:Cholesterol / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D007103:Immobilization; D051381:Rats; D013312:Stress, Physiological / Q000188:drug therapy* / Q000503:physiopathology; D013997:Time Factors
D001965:Bromides; D002784:Cholesterol; D001205:Ascorbic Acid
Morfofunktsional'nye proiavleniia kory nadpochechnikov krys na vvedenie bromida natriia v usloviiakh gipodinamicheskogo stressa