Acute interstitial nephritis.
Acute allergic interstitial nephritis is manifested clinically by rash, fever, eosinophilia, hematuria, oliguria and azotemia. Histologically a monocytic inflammatory process in the renal interstitium is seen. The clinical course of a patient after excessive sodium cephalothin administration suggested allergic interstitial nephritis and implicates this drug as an etiologic agent.
D000208:Acute Disease; D002512:Cephalothin / Q000009:adverse effects*; D004342:Drug Hypersensitivity; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy
D002512:Cephalothin