title: [Immunoglobulins in the gastric juice in some stomach and duodenal diseases].
abstract: IgA, IgM and IgC content in blood serum and gastric juice were determined in 89 patients with different gastric and duodenal diseases (57 with duodenal ulcers, 13 with gastric ulcers 8 with chronic atrophic gastritis, 9 with superficial chronic gastritis and gastroduodenitis and two with gastric cancer). Immunoglobulin was established in gastric juice (over 0,3 mg/100 ml) in 49 per cent of all the patients examined with gastric and duodenal diseases. No correlation was found between serum immunoglobulin level and their presence in the gastric juice. No correlation exists between the volume of the basal secretion and the presence or absence of immunoglobulins in the gastric juice. Immunoglobulins were established more often in the gastric juice with lower secretion of hydrochloric acid (in chronic atrophic gastritis and gastric ulcer), while in cases of higher secretion they are more frequently absent. A certain parallelism was established between the changes of hydrochloric acid output and JgA secretion in the gastric juice after stimulation of gastric secretion by Pentagastrin or histamine.
mesh_terms: D002908:Chronic Disease; D004378:Duodenal Diseases / Q000276:immunology*; D004381:Duodenal Ulcer / Q000276:immunology; D005750:Gastric Juice / Q000276:immunology* / Q000378:metabolism; D005756:Gastritis / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D013272:Stomach Diseases / Q000276:immunology*; D013274:Stomach Neoplasms / Q000276:immunology; D013276:Stomach Ulcer / Q000276:immunology
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins
vernacular_title: Imunoglobulini v stomashniia sok pri niakoi stomashni i duodenalni zaboliavaniia