[Kinetics of the main sections of the hematopoietic system in the process of postradiational regeneration].
After a sublethal (200 rad) irradiation of mice there occurred during the first 24 hours in the bone marrow a marked reduction of the number of the stem (to 4%), committed precursors of granulocytes and macrophages (to 20%) and of the morphologically-identified cells (to 50%). Complete restoration of hemopoiesis was observed by the end of the 2 weeks after the irradiation and was primarily due to the exponential growth of the number of the stem cells and their intensified proliferation. An increase in the number of the committed precursors was retarded to the moment of restoration of the normal amount of cells in the bone marrow.
D000818:Animals; D001772:Blood Cell Count; D001853:Bone Marrow / Q000528:radiation effects; D001854:Bone Marrow Cells; D002999:Clone Cells / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006098:Granulocytes / Q000528:radiation effects; D006410:Hematopoiesis / Q000528:radiation effects; D006412:Hematopoietic Stem Cells / Q000528:radiation effects; D006413:Hematopoietic System / Q000528:radiation effects*; D007700:Kinetics; D008264:Macrophages / Q000528:radiation effects; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D011830:Radiation Effects; D012038:Regeneration / Q000528:radiation effects*; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors; D014316:Tritium
D014316:Tritium; D013936:Thymidine
Kinetika osnovnykh otdelov krovetvornoĭ sistemy v protsesse postradiatsionnoĭ regeneratsii