[Change in the plasmocytic reaction of immunized animals during the use of antibiotics].
The effect of tetracycline and tetraolean on the shifts in the plasma-cell elements was studied experimentally on male albino rats of Wister line and rabbits immunized with foreign erythrocytes and typhoid fever vaccine respectively. It was noted that prolonged use of the antibiotics for 10 to 12 days inhibited proliferation of the plasmic cells, the inhibitory effect of tetracycline being more pronounced. At the same time an inhibitory effect of the antibiotics on the antibody formation in the animals was found in the experiments.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000917:Antibody Formation / Q000187:drug effects; D003864:Depression, Chemical; D007114:Immunization; D008198:Lymph Nodes / Q000276:immunology; D009827:Oleandomycin / Q000494:pharmacology; D010950:Plasma Cells / Q000187:drug effects* / Q000276:immunology; D011817:Rabbits; D051381:Rats; D013752:Tetracycline / Q000494:pharmacology; D013997:Time Factors
D000900:Anti-Bacterial Agents; D013752:Tetracycline; D009827:Oleandomycin
Izmenenie plazmotsitarnoĭ reaktsii u immunizirovannykh zhivotnykh v usloviiakh primeneniia antibiotikov