An electron microscope study of Darier's disease.
An electron microscope investigation was performed on cutaneous biopsies from four patients with Darier's disease. Suprabasal lacunae with acantholytic cells a prominent feature. Basal cells and acantholytic cells showed an increase in tonofilaments. Corps ronds appeared as vacuolated cells.
D000051:Acantholysis / Q000473:pathology; D001706:Biopsy; D007644:Darier Disease / Q000473:pathology*; D003896:Desmosomes / Q000648:ultrastructure; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D012867:Skin / Q000648:ultrastructure*