Contact urticaria and anaphylactoid reaction induced by topical application of nitrogen mustard.
A 36-year-old woman and a 16-year-old boy, both suffering from mycosis fungoides, developed urticaria and an anaphylactoid reaction after topical whole body application of nitrogen mustard. Prick tests with nitrogen mustard solution produced a weal and flare response. Both patients had previously been treated intermittently with total body application of nitrogen mustard for 2 1/2 years and 1 year respectively without complications.
D000293:Adolescent; D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008466:Mechlorethamine / Q000009:adverse effects* / Q000627:therapeutic use; D009182:Mycosis Fungoides / Q000188:drug therapy; D014581:Urticaria / Q000139:chemically induced*
D008466:Mechlorethamine