[Vinylogous acyl compounds. XV. Thin-layer chromatographic detection of 2-halovinyl ketones with toxicological relevance (author's transl)].
The basic ring-opening of 1-(2-acylvinyl)-pyridinium salts yielding azaoxonol dyes and the spontaneous dehydrohalogenation of 1-(2-acylvinyl)-4-(4-nitrobenzyl)-pyridinium salts to deeply coloured anhydrous bases underlie two sensitive thin-layer chromatographic detection procedures for 2-halovinyl ketones (R-CO-CH=CH-X). The detection limits are 0.06 mug on successive use of methanolic solutions of pyridine and potassium hydroxide as spray reagents and 0.02 mug on spraying with an acetonic solution of 4-(4-nitrobenzyl)-pyridine. RF values of twenty-five trans- and twelve cis-configurated 1-halovinyl ketones for three solvent systems are given.
D002855:Chromatography, Thin Layer / Q000379:methods*; D006219:Halogens / Q000032:analysis; D007202:Indicators and Reagents; D007659:Ketones / Q000032:analysis; D011726:Pyridinium Compounds; D012997:Solvents; D014753:Vinyl Compounds / Q000032:analysis*
D006219:Halogens; D007202:Indicators and Reagents; D007659:Ketones; D011726:Pyridinium Compounds; D012997:Solvents; D014753:Vinyl Compounds
Vinyloge Acylverbindungen. XV. Dünnschichtchromatographischer Nachweis toxikologisch relevanter 2-Halogenvinylketone