title: Immunological decay in thymectomized infants.
abstract: Four infants underwent radical thymectomy for a suspected malignancy of the thymus. Histology revealed no malignant cells. The patients did clinically well as long as 14 years after the operation. There was laboratory evidence for a cellular and humoral immunodeficiency. Affected were mainly the response to oral poliomyelitis vaccinations and the skin tests of delayed type hypersensitivity.
mesh_terms: D000293:Adolescent; D000917:Antibody Formation; D002648:Child; D005500:Follow-Up Studies; D006801:Humans; D007111:Immunity, Cellular; D007117:Immunization, Secondary; D007070:Immunoglobulin A / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000209:etiology*; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology; D012882:Skin Tests; D013934:Thymectomy
chemical_list: D007070:Immunoglobulin A