title: [Phamacological studies on bamboo grass (1). Acute toxicity and anti-inflammatory and antiulcerogenic activities of water-soluble fraction(Folin) extracted from Sasa albomarginata Makino et Shibata].
abstract: Folin showed no significant toxic effects in mice. The tail pressure test in mice revealed a potent analgesic effect with a hypothermic effect in rats. A significant decrease was also seen in rat dextran or carrageenin edema. There were no inhibitory effects on the formation of granulation tissue in rats. In addition, Folin administration revealed a tendency to a decrease in pylorus-ligated ulcer of the rat by inhibiting the gastric secretion. Some protective effects from aspirin or caffeine-induced gastric ulcers of the pylorus-ligated rats were also obtained in this fraction.
mesh_terms: D000700:Analgesics; D000818:Animals; D000893:Anti-Inflammatory Agents; D001831:Body Temperature / Q000187:drug effects; D004487:Edema / Q000188:drug therapy; D005750:Gastric Juice / Q000378:metabolism; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D051381:Rats; D013276:Stomach Ulcer / Q000188:drug therapy*
chemical_list: D000700:Analgesics; D000893:Anti-Inflammatory Agents; D010936:Plant Extracts