title: Analgesic activity of dimeric proanthocyanidins--Preliminary experiments.
abstract: Pharmacological experiments with cacao and avocado proanthocyanidins were performed. Analgesic action was measured by the heated plate method: mice receiving 80mg/kg of the drugs showed a behaviour similar to those receiving morphine. Potentiation of "sleeping time" suggests a possible depressive action on the central nervous system.
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D000777:Anesthetics; D000818:Animals; D000872:Anthocyanins / Q000494:pharmacology / Q000627:therapeutic use; D055598:Chemical Phenomena; D002621:Chemistry; D004341:Drug Evaluation; D051379:Mice; D010146:Pain / Q000188:drug therapy
chemical_list: D000700:Analgesics; D000777:Anesthetics; D000872:Anthocyanins