title: [The role of temperature in phenotypic expression of amphibian embryos Pleurodeles waltlii homozygous for the heat-sensitive mutation ac (caudal ascites)].
abstract: 1. At the feeding stage (st. 38), a high percentage (79%) of Pleurodeles homozygous ac/ac larvae show bent tails after a persistent ascitic blister in the dorsal part of the fin, when embryonic development occurred at 12 degrees C; about only 25% of them are affected by abdominal and pericardic ascites; about 40% can feed and survive. The larval phenotype is very different when embryonic development occurred at 23 degrees C, in which case tail growth appears to be normal, but 95% larvae die, due to ascitic fluid collection in the abdominal and heart regions, marked anaemia and microcephaly. 2. The exchange of posterior neural plates and dorso-lateral epidermis between normal and mutant neurulae has shown that the localization of the blister in the dorsal fin is not dependent on autonomous properties of the mutant dorsal tissues, but should be considered as resulting from general disturbances in the mutatnt organism. 3. Experiments were performed, involving a temperature shift from 12 to 23 degrees
mesh_terms: D000367:Age Factors; D000818:Animals; D001201:Ascites; D006720:Homozygote; D006358:Hot Temperature; D007814:Larva / Q000254:growth & development; D009154:Mutation; D010641:Phenotype; D012455:Salamandridae / Q000196:embryology*; D013623:Tail / Q000196:embryology*; D013696:Temperature; D014562:Caudata / Q000196:embryology*
vernacular_title: Recherches sur le rôle de la température dans la réalisation du phénotype chez des embryons de l'Amphibien Pleurodeles waltlii homozygotes pour la mutation thermosensible ac (ascite caudale)