Biochemical assessment of thiamin status in patients with neurosis.
The thiamin status of 65 patients with neurosis was studied soon after their admission to the psychiatric department; 49 healthy persons were also studied. In comparison with the control group, the patients with neurosis had a twice as low thiamin excretion and a 22% lower erythrocyte transketolase (p less than 0.001), while their blood pyruvate and pyruvate excretions were 31-38% higher (p less than 0.001).
D000328:Adult; D003404:Creatinine / Q000097:blood; D004912:Erythrocytes / Q000201:enzymology; D006801:Humans; D009497:Neurotic Disorders / Q000188:drug therapy / Q000378:metabolism*; D011773:Pyruvates / Q000378:metabolism; D013831:Thiamine / Q000378:metabolism* / Q000627:therapeutic use; D013832:Thiamine Deficiency / Q000378:metabolism; D014174:Transketolase / Q000097:blood
D011773:Pyruvates; D003404:Creatinine; D014174:Transketolase; D013831:Thiamine