Pre-trial cocaine and performance in rat.
Cocaine injected pre-trial (10 mg/kg i.p.) improves performance in naive and high-performance (HP) and low-performance (LP) trained rats. When the effect of cocaine is removed, the number of conditioned responses decreases and equals that of drugless sessions. Cocaine favors only performance, not retention.
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D003042:Cocaine / Q000494:pharmacology*; D003214:Conditioning, Classical / Q000187:drug effects*; D004597:Electroshock; D008297:Male; D051381:Rats; D011930:Reaction Time / Q000187:drug effects; D012153:Retention, Psychology / Q000187:drug effects
D003042:Cocaine