Addition of N-acetylcysteine to linoleic acid hydroperoxide.
Catalyzed by 10(-5)M ionic iron in 80% ethanol, N-acetylcysteine added to linoleic acid hydroperoxide, forming a thiobond. Reaction of a specific isomer of hydroperoxide, 13-hydroperoxy-trans-11, cis-9-octadecadienoic acid, and N-acetylcysteine, forms a number of products, of which two were identified as addition compounds. One addition product was 9-S-(N-acetylcysteine)-13-hydroxy-10-ethoxy-trans-11-octadecenoic acid, and the other was 9-S-(N-acetylcysteine)-10, 13-dihydroxy-trans-11-octadecenoic acid.
D000111:Acetylcysteine; D055598:Chemical Phenomena; D002621:Chemistry; D002845:Chromatography; D002855:Chromatography, Thin Layer; D007536:Isomerism; D008041:Linoleic Acids; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010545:Peroxides; D013055:Spectrophotometry, Infrared; D013455:Sulfur
D008041:Linoleic Acids; D010545:Peroxides; D013455:Sulfur; D000111:Acetylcysteine