title: Influence of extracorporeal dialysis on parathyroid hormone secretion in patients with acute renal failure.
abstract: Serum immunoreactive parathyroid hormone (iPTH) was estimated in 30 patients with renal failure before and after haemodialysis. All patients were anuric or oliguric at the time of the investigation. Pre-dialysis iPTH values were significantly elevated (3.4 ng/ml) as compared with normal subjects (less than 0.5 ng/ml). Simultaneously, a significant hypocalcaemia (4.15 mEq/litre) was confirmed which was negatively correlated with iPTH levels. After 7-8 h of haemodialysis using a calcium concentration of 4.0 mEq/litre in the dialysate, a significant drop of iPTH level to 1.8 ng/ml was noted.
mesh_terms: D058186:Acute Kidney Injury / Q000150:complications / Q000378:metabolism* / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000209:etiology; D006996:Hypocalcemia / Q000150:complications / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood / Q000276:immunology / Q000378:metabolism*; D006435:Renal Dialysis
chemical_list: D010281:Parathyroid Hormone