title: Brain wave components of the contingent negative variation in humans.
abstract: In a contingent negative variation paradigm with two stimuli paired at an interstimulus interval of 4 seconds, two distinct waveforms having functional and topographic differences are observed. An early wave is maximal over the frontal cortex and is elicited by the warning stimulus. A later wave, maximal over the motor cortex, precedes the imperative stimulus and is identified with preparation for motor response.
mesh_terms: D001921:Brain / Q000502:physiology*; D003265:Contingent Negative Variation; D004594:Electrophysiology; D005260:Female; D006801:Humans; D008297:Male; D009044:Motor Cortex / Q000502:physiology; D010296:Parietal Lobe / Q000502:physiology