[The relationship between the doubling time of human lung tumor volume and the labelling index].
The value of the labelling index (incubation with H3-thymidine) was compared with the doubling time of tumour volume (by repeated roentgenograms) for 3 tumours of human lungs: two squamous cell carcinomas taken at various differentiation levels and a hamartoma. The minimum doubling time (178 days) was shown for the squamous cell carcinoma with a lower differentiation level and the greatest labelling index value (19.0%). Hamartoma (a non-malignant tumour of lung) displayed the longest doubling time (1250 days) and the least labelling index value (3.8%).
D002294:Carcinoma, Squamous Cell / Q000378:metabolism / Q000503:physiopathology*; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D006222:Hamartoma / Q000378:metabolism / Q000503:physiopathology*; D006801:Humans; D008175:Lung Neoplasms / Q000378:metabolism / Q000503:physiopathology*; D013936:Thymidine / Q000378:metabolism*
D004273:DNA, Neoplasm; D013936:Thymidine
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