Metabolic changes in newborn infants following surgical operations. I. Blood levels of glucose, plasma free fatty acids, alpha-amino nitrogen, plasma amino acid ratio and urea nitrogen.
In 29 newborn infants subjected to surgery for congenital anomalies, the blood glucose, free fatty acid (FFA), amino acid, alpha-amino nitrogen and blood urea levels were observed from the first to the seventh postoperative days. The blood glucose level showed moderate changes in the postoperative period, while FFA decreased significantly. The combined concentration of non-essential amino acids (glycine + glutamine + serine + taurine) and that of essential amino acids (leucine + isoleucine + valine + methionine), their quotient (Whitehead's ratio), as well as the alpha-amino nitrogen level indicated dynamic changes in the postoperative period. The gradual return of blood urea to the preoperative level is explained by the diminished breakdown and the improved excretory function of the kidney following surgical procedures.
D000596:Amino Acids / Q000097:blood; D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000601:surgery; D007668:Kidney / Q000378:metabolism; D008297:Male; D009584:Nitrogen / Q000097:blood; D011183:Postoperative Complications; D011247:Pregnancy; D014508:Urea / Q000097:blood
D000596:Amino Acids; D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D014508:Urea; D009584:Nitrogen