Influence of volume expansion on sodium excretion during parabiotic dialysis.
Dialysis of a saline-infused against a noninfused dog was associated with a significant increase in Na excretion in both animals without a significant change in creatinine clearance or filtered Na. This indicates that there was movement by diffusion of a humoral agent between the two animals. The observed increase in Na excretion in the noninfused animal resulted from gain of a natriuretic hormone, since in a second series of experiments a natriuretic rather than antinatriuretic hormone appeared to be involved.
D000818:Animals; D001810:Blood Volume; D004231:Diuresis; D004285:Dogs; D007668:Kidney / Q000502:physiology; D007677:Kidney Function Tests; D007688:Kidneys, Artificial; D009318:Natriuresis; D010227:Parabiosis; D006435:Renal Dialysis; D012965:Sodium Chloride / Q000494:pharmacology
D012965:Sodium Chloride