Central metabolic and humoral factors involved in the neural regulation of feeding.
Evidence is summarized for the theory that long-term regulation of energy balance is elaborated by an interface between matabolism and brain activity within the medial hypothalamus, while short-term satiety effects are a more direct consequence of dampened activity in lateral hypothalamic feeding circuits. Possible relationships of these functions to autonomic control circuits are discussed.
D000273:Adipose Tissue / Q000378:metabolism; D000375:Aging; D000596:Amino Acids / Q000494:pharmacology; D000818:Animals; D002940:Circadian Rhythm; D003847:Deoxyglucose / Q000494:pharmacology; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism; D004041:Dietary Fats; D004435:Eating; D005215:Fasting; D005247:Feeding Behavior / Q000187:drug effects; D005947:Glucose / Q000494:pharmacology; D007031:Hypothalamus / Q000187:drug effects / Q000254:growth & development / Q000502:physiology*; D008041:Linoleic Acids / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008954:Models, Biological; D010101:Oxygen Consumption; D051381:Rats; D013997:Time Factors; D014508:Urea / Q000494:pharmacology
D000596:Amino Acids; D004041:Dietary Fats; D008041:Linoleic Acids; D014508:Urea; D003847:Deoxyglucose; D005947:Glucose