[Hypophyseal mast cells].
The content of mast cells and their morphological formula were studied in 30 dogs under a different activity of the neuro-endocrine system, with determination of the sectional plane of nuclei in hormon-producing cells of the adenohypophysis and content of neuro-secret in the neurohypophysis. It is shown that activation of the neuro-endocrine system by means of injection of adrenaline brought about an increase in the number of mast cells without shifts in their formula, which correlated with the reduction in the level of neuro-secret and with the enlargement of nuclei of adenohypophyseal cells. The effect effect of chronic overloadings could be seen from an increased percentage of degranulating mast cells in the all departments of the hypophysis with impairment of the microcirculation in the organ. A clear-cut correlational relationship between the number of mast cells containing biologically active amines and morphometric indices of the functional activity of the adenohypophysis enabled the authors to put forward a supposition that mast cells may serve as an indirect index of the hypophyseal activity.
D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure; D003594:Cytoplasmic Granules; D004285:Dogs; D008407:Mast Cells / Q000166:cytology*
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