Abnormal tryptophan metabolism and experimental diabetes by xanthurenic acid (XA).
1) Xanthurenic acid-insulin complex reduced insulin activity. 2) The antigenicity of xanthurenic acid-insulin was almost same as native insulin. 3) Saturated fat increased urinary xanthurenic acid in vitamin B6 deficiency.
D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000378:metabolism*; D006019:Glycolysis; D006168:Guinea Pigs; D007328:Insulin / Q000097:blood; D008297:Male; D011817:Rabbits; D051381:Rats; D014364:Tryptophan / Q000378:metabolism*; D026681:Vitamin B 6 Deficiency / Q000378:metabolism; D014977:Xanthurenates / Q000378:metabolism*
D001786:Blood Glucose; D007328:Insulin; D014977:Xanthurenates; D014364:Tryptophan