title: Perforation of nasal septum in rheumatic diseases.
abstract: Perforation of the nasal septum was noted in 12 patients with rheumatic disease, including rheumatoid arthritis (RA), psoriatic arthritis (PsA), systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS), and mixed connective tissue disease (MCTD). Biopsies were taken from the rim of the perforation in 7 of the 12 and revealed no vasculitis, immunoglobulin deposition, or consistent abnormality. Nasal septal perforation is an occasional finding in rheumatic disease and the cause is unknown.
mesh_terms: D000328:Adult; D000368:Aged; D001168:Arthritis / Q000150:complications*; D001172:Arthritis, Rheumatoid / Q000150:complications; D003095:Collagen Diseases / Q000150:complications*; D004844:Epistaxis / Q000209:etiology; D005260:Female; D006801:Humans; D007511:Ischemia / Q000209:etiology; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008297:Male; D008875:Middle Aged; D009300:Nasal Septum / Q000098:blood supply; D009668:Nose Diseases / Q000209:etiology; D011565:Psoriasis / Q000150:complications; D011928:Raynaud Disease / Q000150:complications; D012595:Scleroderma, Systemic / Q000150:complications