[Biological action of cement dust in intraperitoneal and intratracheal tests].
The morphological changes occuring upon intraperitoneal and intratracheal application of cement with free silica content amounting to 1.30% are described. Initially, the changes in the peritoneal cavity are mainly necrotic and exudative, while after subsiding, the granulomas formed around the uneliminated dust particles predominate without exhibiting fibrotic phenomena. Upon intratracheal application, lesions typical of cement occur, coined by the authors with the term "experimental cement pneumopathy". It is a matter of changes presenting as "pseudopolyp" formations around the small bronchi and bronchioli, slipping into their lumen and thus causing its obturation. In the final stages of the experiment, a definitive peribronchial fibrosis with perifocal and subpleural emphysema is developed around the involved bronchi.
D000005:Abdomen / Q000187:drug effects; D000818:Animals; D001980:Bronchi / Q000187:drug effects; D003252:Construction Materials / Q000009:adverse effects*; D004391:Dust; D007267:Injections; D007274:Injections, Intraperitoneal; D007928:Lethal Dose 50; D008168:Lung / Q000187:drug effects; D008297:Male; D051379:Mice; D009336:Necrosis; D051381:Rats; D013997:Time Factors; D014132:Trachea
D004391:Dust
Vurkhu biologichnoto vuzdeĭstvie na tsimentoviia prakh pri intraperitonealniia i intratrakhealniia test.