99Tcm-solcocitran in the detection of bone malignancy.
A new 99Tcm-labelled compound, 99Tcm-Solcocitran, has been introduced for detection of bone and brain malignancy. It is claimed to be specific for neoplastic tissue. In the present material, however, 99Tcm-Solcocitran was less sensitive in indicating metastatic bone lesions in patients than was 99Tcm-Diphosphonate or conventional radiography. Both 99Tcm compounds accumulated in fractures in dogs. 99Tcm-Solcocitran seems to offer no advantage over existing techniques in the detection of bone malignancy.
D000818:Animals; D001859:Bone Neoplasms / Q000175:diagnosis*; D002951:Citrates / Q000378:metabolism; D004285:Dogs; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D063065:Organophosphonates / Q000378:metabolism; D011877:Radionuclide Imaging / Q000295:instrumentation; D013667:Technetium / Q000378:metabolism; D014001:Tin
D002951:Citrates; D063065:Organophosphonates; D013667:Technetium; D014001:Tin