Placental transfer of tritium-labelled prostaglandin A1 in the rat.
Pregnant Long Evans rats were treated with 25 muCi 3 H-prostaglandin A1 on either gestational day 15, 18 or 21. The highest concentrations of radioactivity were found in maternal kidneys, lungs and liver. The levels of radioactivity in the gut and also in amniotic fluid markedly increased with time after isotope administration. Significant levels of radioactivity were present in fetal tissues and in the placenta.
D000818:Animals; D005260:Female; D005333:Fetus / Q000378:metabolism; D005865:Gestational Age; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D008431:Maternal-Fetal Exchange; D009206:Myocardium / Q000378:metabolism; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D011454:Prostaglandins A / Q000378:metabolism*; D051381:Rats; D014316:Tritium; D014599:Uterus / Q000378:metabolism
D011454:Prostaglandins A; D014316:Tritium