Microbial degradation of steroid alkaloids. Effect of nitrogen atom in the side-chain on the microbial degradation of steroid alkaloids.
The microbial dehydrogenation of steroid alkaloids follows the dehydrogenation pattern of steroids until the 3-keto-1,4-diene stage. No side-chain cleavage or degradation of the steroid nucleus is observed. Side-chain cleavage of tomatidine is achieved only by previous induction of side-chain splitting enzymes.
D000470:Alkaloids / Q000378:metabolism*; D001419:Bacteria / Q000378:metabolism*; D001673:Biodegradation, Environmental; D055598:Chemical Phenomena; D002621:Chemistry; D005658:Fungi / Q000378:metabolism*; D005670:Fusarium / Q000378:metabolism; D009161:Mycobacterium / Q000378:metabolism; D009584:Nitrogen / Q000378:metabolism; D009615:Nocardia / Q000378:metabolism; D013256:Steroids / Q000378:metabolism*; D013302:Streptomyces / Q000378:metabolism; D014053:Tomatine / Q000378:metabolism
D000470:Alkaloids; D013256:Steroids; D014053:Tomatine; D009584:Nitrogen