[In-vitro and in-vivo studies on the percutaneous absorption of systemic P 32-labelled insecticide organophosphorus compounds in cattle].
The influence of chemical composition and formulation on the absorption of radiophosphorus-labelled trichlorphon, butonate and dimethoate was investigated with isolated strips of bovine skin. Other factors studied were polarity of the solvent, concentration of pesticide, and effect of surface-active agents and dimethyl sulphoxide. Absorption experiments were also carried out on cattle and sheep, and the results were compared with those of the in vitro tests.
D000818:Animals; D002417:Cattle / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D004117:Dimethoate / Q000378:metabolism; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D066298:In Vitro Techniques; D007306:Insecticides / Q000378:metabolism*; D010759:Phosphorus Isotopes; D012756:Sheep / Q000378:metabolism; D012867:Skin / Q000378:metabolism; D012869:Skin Absorption / Q000187:drug effects; D013501:Surface-Active Agents / Q000494:pharmacology; D014236:Trichlorfon / Q000378:metabolism
D007306:Insecticides; D010759:Phosphorus Isotopes; D013501:Surface-Active Agents; D014236:Trichlorfon; D004117:Dimethoate; D004121:Dimethyl Sulfoxide
Studien in vitro und in vivo zur perkutanen Resorption systemischer 32P-markierter insektizider Organophosphorverbindungen am Rind