title: Aseptic meningitis as a complication of scinticysternography utilizing 111Indium-dtpa.
abstract: The intrathecal administration of numerous substances has been known to cause arachnoiditic as well as aseptic meningitic reactions. Pleocytosis and increased protein in the CSF are well known findings following administration of air or myelographic dyes. This has also been observed with antibiotics. Even intrathecal steroids (e.g. depo-medrol) have been implicated in aseptic meningitic reactions. Despite the wide variety of causative agents, only a small percentage of patients develop clinical manifestations of aseptic meningitis. Are these reactions then caused by specific auto-immune type responses, or are they directly related to local irritants in each case, or a combination of both factors?
mesh_terms: D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D007204:Indium / Q000633:toxicity*; D008581:Meningitis / Q000139:chemically induced*; D008582:Meningitis, Aseptic / Q000134:cerebrospinal fluid / Q000139:chemically induced*; D008875:Middle Aged; D009192:Myelography / Q000009:adverse effects*; D004369:Pentetic Acid / Q000633:toxicity*
chemical_list: D007204:Indium; D004369:Pentetic Acid