title: Ultrastructural response of hepatocytes to thymectomy and pregnenolone-16alpha-carbonitrile.
abstract: In young female rats, thymectomy causes RER alterations and a slight increase in SER. PCN augments SER in the hepatocytes of both intact and thymectomized rats. Thymectomy prolongs zoxazolamine paralysis and PCN treatment decreases the duration of zoxazolamine paralysis both in intact and operated rats.
mesh_terms: D000818:Animals; D004790:Enzyme Induction / Q000187:drug effects; D005260:Female; D008099:Liver / Q000648:ultrastructure*; D008862:Microsomes, Liver / Q000187:drug effects; D011284:Pregnenolone / Q000494:pharmacology*; D051381:Rats; D013934:Thymectomy
chemical_list: D011284:Pregnenolone