[The effect of caudate nucleus stimulation on phenamine stereotypy in cats].
Large doses of d,1-amphetamine produce in cats a stereotype behaviour: its chronic administration results in low variability of the behaviour of one and the same animal and a stable set of motor automatisms. This makes it possible to use the cyclography for an objective estimation of the d,1-amphetamine-induced stereotypy. Low-frequency stimulation of the caudate nucleus head weakens or completely blocks the sterotype movements when current intensity is subthreshold for behavioral arrest reaction. The pecularities of the caudate control its similarity to the action of haloperidol and the absence of influence of the stimulation of the capsula interna and some thalamic nuclei on the stereotypy lead to the assumption that it is due to the depression of the inhibitory function of the caudate nucleus brought about by the intensification of the nigro-striatal dopaminergic transmission.
D000661:Amphetamine / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D000818:Animals; D001519:Behavior / Q000502:physiology*; D001522:Behavior, Animal / Q000187:drug effects*; D002415:Cats; D002421:Caudate Nucleus / Q000502:physiology*; D004558:Electric Stimulation; D005260:Female; D006220:Haloperidol / Q000494:pharmacology; D006801:Humans; D008297:Male; D009043:Motor Activity / Q000187:drug effects / Q000502:physiology; D013239:Stereotyped Behavior / Q000502:physiology*
D000661:Amphetamine; D006220:Haloperidol
Vliianie razdrazheniia khvostatogo iadra na fenaminovuiu stereotipiiu u koshek