The influence of polymorphonuclear leukocytes and macrophages on the growth of lymphocytes and fibroblasts in vitro.
The influence of polymorphonuclear leukocytes (PMNL) and macrophage plasma, nuclei and lysosome extracts have been tested on lymphocytes and fibroblasts growth in vitro. The stimulatory activity of PMNL lysosomes has been shown on lymphocyte and fibroblast growth. The macrophage lysosomes have shown a similar but lower activity. The role of lysosomes has been suggested in reparation and wound healing processes, presumably in inflammatory cell infiltrated regions.
D000818:Animals; D000917:Antibody Formation; D005347:Fibroblasts / Q000502:physiology*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D037102:Lectins; D007962:Leukocytes / Q000276:immunology*; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000502:physiology*; D008247:Lysosomes / Q000276:immunology; D008264:Macrophages / Q000276:immunology*
D037102:Lectins