On the design of clinical chemistry quality-control sera.
Quality-control specimens having quantitave interspecimen relationships were prepared by (a) making admixtures of two serum pools and (b) making various dilutions of the admixtures. The specimens were analyzed for many constituents to illustrate how the data obtained could be manipulated and used. The inter-related specimens permit the reduction of quality-control data to a few target values and should be particularly useful for the evaluation of multi-channel analyzers, and for use in inter-laboratory proficiency surveys. Aspects of the design of quality control and proficiency test specimens are also discussed.
D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001774:Blood Chemical Analysis / Q000592:standards*; D001786:Blood Glucose / Q000032:analysis; D001806:Blood Urea Nitrogen; D002118:Calcium / Q000097:blood; D002712:Chlorides / Q000097:blood; D003402:Creatine Kinase / Q000097:blood; D003404:Creatinine / Q000097:blood; D005069:Evaluation Studies as Topic; D006801:Humans; D007501:Iron / Q000097:blood; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008274:Magnesium / Q000097:blood; D010758:Phosphorus / Q000097:blood; D011188:Potassium / Q000097:blood; D011786:Quality Control; D012964:Sodium / Q000097:blood; D014527:Uric Acid / Q000097:blood
D001786:Blood Glucose; D002712:Chlorides; D007527:Isoenzymes; D014527:Uric Acid; D010758:Phosphorus; D012964:Sodium; D003404:Creatinine; D007501:Iron; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase; D000469:Alkaline Phosphatase; D008274:Magnesium; D011188:Potassium; D002118:Calcium