title: Studies on the species, amount and base composition of nucleic acids in psoriatic scales and normal horny layer.
abstract: The amount of RNA as well as DNA is considerably increased in psoriatic scales as compared with normal horny layer; RNA was characterized as a low-molecular tRNA; as concerns the base composition of DNA, no particularities in comparison with other DNA species were found, and the base composition of tRNA revealed that cytosine and guanosine are in excess; pseudouridine could not be detected in psoriatic tRNA.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002845:Chromatography; D004247:DNA / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D006868:Hydrolysis; D008875:Middle Aged; D009705:Nucleosides / Q000032:analysis; D010783:Photometry; D011565:Psoriasis / Q000378:metabolism*; D012343:RNA, Transfer / Q000032:analysis / Q000378:metabolism*; D012867:Skin / Q000378:metabolism*
chemical_list: D009705:Nucleosides; D004247:DNA; D012343:RNA, Transfer