Study of relatives of persons with fibrillopathia epitheliocapsularis (pseudoexfoliation of the lens capsule).
The frequency of fibrillopathy (pseudoexfoliation of the lens capsule) among relatives of persons with fibrillopathy was investigated. Among 203 relatives over the age of 40 years, belonging to 25 families, fibrillopathy was found in 19, or in almost 10%. The frequency was independent of whether the proband had capsular glaucoma or normal intraocular pressure. Capsular glaucoma occurred in five of the 19 relatives. The results suggest that fibrillopathy may occur as a dominant hereditary trait, but it may also be found sporadically.
D000328:Adult; D000367:Age Factors; D000368:Aged; D005128:Eye Diseases / Q000235:genetics*; D005260:Female; D005901:Glaucoma / Q000235:genetics; D006801:Humans; D007908:Lens, Crystalline; D008297:Male; D008875:Middle Aged; D012737:Sex Factors