[Processes of chromosome damage repair in unstimulated human peripheral blood lyphocytes by the method of fractional irradiation and temperature variation].
The fractionation experiments were carried out on resting lymphocytes. Non-stimulated lymphocytes were X-irradiated at the total dose of 200 r separated into two equal parts by either 5-hour or 20-hour intervals. The whole blood samples were kept during the intervals between the exposure at the temperature of 20 degrees centigrade or 37 degrees centigrade. All the cultures were made after the last radiation exposure at 37 degrees centigrade. Dicentrics and centric rings were scored. It is shown that a fractionation effect takes place in resting lymphocytes when the whole blood was kept for intervals between the half-dose at 37 degrees centigrade and is absent at the temperature of 20 degrees centigrade. It is suggested that there is the repair in lymphocytes at the stage G0, AT least, from the dose of 100 r.
D002875:Chromosomes / Q000528:radiation effects*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008875:Middle Aged; D011829:Radiation Dosage; D011831:Radiation Genetics; D013696:Temperature
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