[Experimental contribution to the study of the anticellular effect of diphenyl mercury (author's transl)].
The effect of diphenyl mercury on the chick embryo erythroblastic cell population and rat's bone marrow cells has been studied. The predominant cytologically observed effect of this compound was the c-mitotic action. Besides the well known capacity of spindle inactivation, the diphenyl mercury was able to induce chromosome fragmentation; a radiomimetic action of the compound is suggested.
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects*; D001854:Bone Marrow Cells; D002642:Chick Embryo; D002875:Chromosomes / Q000187:drug effects; D004912:Erythrocytes / Q000187:drug effects*; D066298:In Vitro Techniques; D008628:Mercury / Q000494:pharmacology*; D008938:Mitosis / Q000187:drug effects*; D009942:Organometallic Compounds / Q000494:pharmacology*; D011838:Radiation-Sensitizing Agents; D051381:Rats
D009942:Organometallic Compounds; D011838:Radiation-Sensitizing Agents; D008628:Mercury
Contributo sperimentale allo studio dell-effetto anticellulare del difenilmercurio