[Chronic infection of cells with tick-borne encephalitis virus. Further characteristics of the system].
From HEp-2 cells chronically infected with tick-borne encephalitis virus clones were obtained which produced no virus antigens and contained no sequences homologous to virus RNA. Expression of oncornavirus in the system under study was demonstrated. The possibility of transduction of cell genes by a defective virus strain was established. Preliminary experiments showed the possibility of integration of virus genome in tick egg DNA in transovarial transmission.
D002460:Cell Line; D002999:Clone Cells; D004247:DNA; D004669:Encephalitis Viruses, Tick-Borne / Q000254:growth & development*; D009693:Nucleic Acid Hybridization; D012367:RNA, Viral; D014161:Transduction, Genetic; D014779:Virus Replication
D012367:RNA, Viral; D004247:DNA
Khronicheskaia infektsiia kletok virusom kleschchevogo éntsefalita. Dopolnitel'naia kharakteristika sistemy