Comparative toxicological studies of indole, benzo[b] thiophene, and 1-methylindole derivatives.
The comparative LD50 values have been determined in mice for 34 indole, benzo[b] thiophene, and 1-methylindole derivatives of related structures. No clear-cut correlations could be obtained with regard to physicochemical properties across all structures although some relationships are evident within subgroups.
D000818:Animals; D007211:Indoles / Q000633:toxicity*; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D013876:Thiophenes / Q000633:toxicity*
D007211:Indoles; D013876:Thiophenes