[Cytostatic chemotherapy and sensitivity tests (oncobiograms) (author's transl)].
The success of cytostatic chemotherapy depends on the numerous factors. Thus, apart from pharmacokinetic and cell kinetic factors, particular attention is being attached to the resistance at cell-biochemical level. In the past decade, a number of screening tests has been devised to avoid the use of ineffective cytostatic drugs in therapeutic schedules. The use of organ culture technique is described for cytostatic sensitivity tests in patients with operated bronchial carcinoma.
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001984:Bronchial Neoplasms / Q000188:drug therapy* / Q000473:pathology; D002463:Cell Membrane Permeability; D002465:Cell Movement; D002478:Cells, Cultured; D004273:DNA, Neoplasm / Q000096:biosynthesis; D004341:Drug Evaluation; D004351:Drug Resistance; D006801:Humans; D009924:Organ Culture Techniques; D011182:Postoperative Care
D000970:Antineoplastic Agents; D004273:DNA, Neoplasm
Chemotherapeutische Studien unter Berücksichtigung des Onkobiogramms