title: Prediction of creatinine clearance from serum creatinine.
abstract: A formula has been developed to predict creatinine clearance (Ccr) from serum creatinine (Scr) in adult males: (see article)(15% less in females). Derivation included the relationship found between age and 24-hour creatinine excretion/kg in 249 patients aged 18-92. Values for Ccr were predicted by this formula and four other methods and the results compared with the means of two 24-hour Ccr's measured in 236 patients. The above formula gave a correlation coefficient between predicted and mean measured Ccr's of 0.83; on average, the difference predicted and mean measured values was no greater than that between paired clearances. Factors for age and body weight must be included for reasonable prediction.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001835:Body Weight; D003404:Creatinine / Q000097:blood* / Q000652:urine; D006801:Humans; D007668:Kidney / Q000502:physiology*; D008297:Male; D008433:Mathematics; D008722:Methods; D008875:Middle Aged
chemical_list: D003404:Creatinine