Histamine receptors in the cat mesenteric circulation.
The distribution of histamine receptors was studied in the isolated perfused vascular bed of the cat terminal ileum. The results indicated that the depressor effect of histamine is mediated through the stimulation of metiamide-sensitive H2-receptors, while the pressor effect of the amine is mediated by the stimulation of mepyramine-sensitive H1-receptors.
D000818:Animals; D002415:Cats; D010478:Chemotherapy, Cancer, Regional Perfusion; D004305:Dose-Response Relationship, Drug; D006632:Histamine / Q000494:pharmacology*; D007082:Ileum; D008638:Mesenteric Arteries / Q000187:drug effects*; D008785:Metiamide / Q000494:pharmacology; D011312:Pressure; D011738:Pyrilamine / Q000494:pharmacology; D011955:Receptors, Drug
D011955:Receptors, Drug; D008785:Metiamide; D006632:Histamine; D011738:Pyrilamine