[Study of the therapeutic effectiveness of oxacillin in treating the infectious forms of syphilis].
Data on efficiency of oxacillin therapy as applied to 45 patients with contagious forms of syphilis are presented. The drug was administered orally and intramuscularly to 40 and 5 patients respectively for 20 days. The periods of clearance from Trepanoma pallidum, disappearance of the external syphilis manifestations and the rate of the decrease in the titer of the serological reaction reagins are presented. The levels of oxacillin in the blood serum of 24 patients were determined for 5--6 hours from the moment of the treatment beginning. The study showed therapeutic efficiency of oxacillin.
D000293:Adolescent; D000328:Adult; D001682:Biological Availability; D002214:Capsules; D004341:Drug Evaluation; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D010068:Oxacillin / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D012075:Remission, Spontaneous; D013587:Syphilis / Q000188:drug therapy*; D013607:Tablets; D013997:Time Factors
D002214:Capsules; D013607:Tablets; D010068:Oxacillin
Izuchenie terapevticheskoĭ éffektivnosti oksatsillina pri lechenii bol'nykh zaraznymi formami sifilisa