title: [Chronic pseudomalignant immuneproliferation (Canale-Smith syndrome) (author's transl)].
abstract: A case of chronic lymphadenopathy and splenomegaly existing over a period of 11 years, with a variety of acquired deficiencies of immunity and autoimmune phenomena, is described. It is almost identical with the 5 children reported in 1967 by Canale and Smith as a new benign syndrome "chronic lymphadenopathy simulating malignant lymphoma". The relationship to similar disorders with lymphadenopathy and immunological abnormalities is discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications; D001327:Autoimmune Diseases / Q000175:diagnosis*; D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D006942:Hypergammaglobulinemia / Q000175:diagnosis*; D007070:Immunoglobulin A / Q000032:analysis; D008198:Lymph Nodes / Q000473:pathology; D008199:Lymphadenitis / Q000175:diagnosis* / Q000276:immunology; D008206:Lymphatic Diseases / Q000175:diagnosis; D008223:Lymphoma / Q000175:diagnosis; D008297:Male; D012507:Sarcoidosis / Q000175:diagnosis; D013163:Splenomegaly / Q000175:diagnosis* / Q000276:immunology; D013577:Syndrome; D013921:Thrombocytopenia / Q000276:immunology
chemical_list: D007070:Immunoglobulin A
vernacular_title: Chronische pseudomaligne Immunproliferation (Canale-Smith-Syndrom)