[Inhalations with L-arginine in the treatment of cystic fibrosis (author's transl)].
12 patients were treated with L-arginine hydrochloride 1-3 times per day for a period of 4 till 8 weeks. All children had been in control in our hospital longer than one-year. The patients received beside administration of digestant enzymes and vibration massages, inhalations with N-acetylcystein (Mucosolvin). The frequency of the daily inhalations was not changed. We compared the results of clinical, x-rays scintigraphic and laboratory investigations during the period of N-acetylcysteine treatment and after the administration of L-arginine. The mucolytic effect by L-arginine is much less than by N-acetylcystein.
D000293:Adolescent; D000336:Aerosols; D000410:Alanine Transaminase / Q000097:blood; D001120:Arginine / Q000627:therapeutic use*; D001219:Aspartate Aminotransferases / Q000097:blood; D001786:Blood Glucose; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000097:blood; D003550:Cystic Fibrosis / Q000097:blood / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011859:Radiography; D014783:Viscosity
D000336:Aerosols; D001786:Blood Glucose; D001120:Arginine; D003404:Creatinine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
Mukolytische Inhalationsbehandlung mit L-Argininhydrochlorid bei Mukoviszidose-Patienten