title: Low molecular weight proteinuria.
abstract: Low molecular weight (LMW) proteinurias vary widely in their microprotein composition. In general, there is little correlation between a given microprotein composition and a defined clinical disease (with the exception of the predominant beta-2-microglobulin in Wilson's disease). Free immunoglobulin light chains are a practically invariable component of, and may be the only detectable LMW protein in, 'tubular' proteinuria. The origins and significance of some frequently occurring urinary LMW proteins are discussed.
mesh_terms: D000328:Adult; D006801:Humans; D007074:Immunoglobulin G / Q000652:urine; D007223:Infant; D007674:Kidney Diseases / Q000150:complications / Q000652:urine; D007687:Kidney Tubules, Proximal / Q000503:physiopathology; D008970:Molecular Weight; D011507:Proteinuria / Q000209:etiology / Q000503:physiopathology / Q000652:urine*
chemical_list: D007074:Immunoglobulin G