Tissue antigens and cytotoxic antibodies in polycythaemia rubra vera.
The distribution of tissue antigens for 22 antigens was studied in 46 patients suffering from polcythaemia rubra vera (PRV), using antibody containing sera from 80 multigravidae. The incidence of HL-A5 was significant higher and that of HL-A7 significant, while the frequency of HL-A13 was remarkably lower than in the normal population. No antibodies against erythrocytes, thrombocytes or lymphocytotoxic ones could be demonstrated.
D000906:Antibodies / Q000032:analysis*; D001782:Blood Donors; D001792:Blood Platelets / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D004912:Erythrocytes / Q000276:immunology; D005787:Gene Frequency; D006680:HLA Antigens / Q000032:analysis*; D006649:Histocompatibility Antigens / Q000032:analysis*; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D011087:Polycythemia Vera / Q000276:immunology*
D000906:Antibodies; D006680:HLA Antigens; D006649:Histocompatibility Antigens