title: Inhibition by prednisone of late cutaneous allergic responses induced by antiserum to human IgE.
abstract: Dual cutaneous allergic responses can be induced in human subjects by the intracutaneous injection of antiserum to human IgE (AHIGE). Adrenocortical steroid fails to inhibit the AHIGE-induced early wheal-and-flare response but does inhibit the late allergic response. This pattern of inhibition by adrenocortical steroid resembles that known to pertain to allergen-induced dual cutaneous allergic responses.
mesh_terms: D006801:Humans; D006967:Hypersensitivity / Q000209:etiology*; D007106:Immune Sera / Q000008:administration & dosage; D007073:Immunoglobulin E; D011241:Prednisone / Q000494:pharmacology*; D012867:Skin / Q000276:immunology*; D012882:Skin Tests; D013997:Time Factors
chemical_list: D007106:Immune Sera; D007073:Immunoglobulin E; D011241:Prednisone