Trisomy-D in a cyclops with cardiovascular defects.
A case report of cyclops with trisomy-D in a female infant, associated with cardiovascular defects is presented. A survey of the literature pertaining to other reported cases of cyclopia is presented to establish the probablity of the existence of at least two distinct etiologic groups of cyclopia--those associated with trisomy-D and those associated with other chromosomal aberrations, single gene mutations, or non-genetic factors.
D009008:Abnormalities, Severe Teratoid / Q000235:genetics*; D000328:Adult; D002901:Chromosomes, Human, 13-15; D005260:Female; D006330:Heart Defects, Congenital / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D014314:Trisomy