The effects of removal of sodium ions from the mucosal solution on sugar absorption by rabbit ileum.
Net absorption and accumulation of D-galactose, beta-methyl D-glucose and low concentrations of 3-0-methyl-D-glucose by sheets of rabbit ileum are observed even when Na+ in the mucosal solution is replaced by choline. This indicates that active sugar transport can occur in the direction opposite to the brush-border Na+ gradient.
D000818:Animals; D001692:Biological Transport; D001693:Biological Transport, Active; D002794:Choline / Q000494:pharmacology; D005690:Galactose / Q000378:metabolism*; D007082:Ileum / Q000187:drug effects / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism*; D008757:Methylglucosides / Q000378:metabolism*; D008759:Methylglycosides / Q000378:metabolism*; D011817:Rabbits; D012964:Sodium / Q000494:pharmacology*
D008757:Methylglucosides; D008759:Methylglycosides; D012964:Sodium; D002794:Choline; D005690:Galactose