title: Glucose transport in the short loop of Henle of the rat kidney. Its characterisation by transport constants.
abstract: Short loops of Henle in rat kidneys were perfused with proximal tubular equilibrium solutions containing radioactive D-glucose. The transport rates follow 2-parameter kinetics: Km = 5.7 mmol/I. Vmax - 145 X 10(-12) MOL/MIN-1; Phlorrhizin inhibits transport almost completely, indicating little passive diffusion of D-glucose. The glucose transport capacity in the short loops of Henle, presumably in the pars rects, is much smaller than that in superficial segments.
mesh_terms: D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D004058:Diffusion; D005260:Female; D005947:Glucose / Q000037:antagonists & inhibitors / Q000378:metabolism*; D007684:Kidney Tubules / Q000378:metabolism*; D008138:Loop of Henle / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010695:Phlorhizin / Q000494:pharmacology; D051381:Rats / Q000378:metabolism*
chemical_list: D010695:Phlorhizin; D005947:Glucose