[Etiology and clinical diagnosis of diffuse pleural mesothelioma (author's transl)].
Diffuse malignant mesothelioma are no longer uncommon diseases within the geographical regions of Halle and Merseburg. These tumors are provoked by the deposition of dust particles of asbestos near the pleura. Asbestos particles are not only obtained by mining and preparation the mineral but also in its use for various purposes - in the past in shipyards mainly and now in the chemical industry as well. The period from the first absorption of these dust particles up to the manifestation of the malignoma is said to last 20-40 years approximately. At present, asbestos is contained in a remarkable great variety of products. Consequently, there is now a general danger, independently of the profession concerned. Possibilities of an exact clinical diagnosis will be discussed on the basis of the experience gained with 100 cases. Only with 17 out of 100 cases the oncogenesis was not accompanied by pleural exudation. The Female/male ratio was 1.0/4.5. 1 - the demonstration of mesothelial cell structures by the transthoracic tumour punctate.  2 - the cytological findings of the effusion cell sediment in connection with the determination of the WELTMANN coagulation band in the effusion and in the blood serum or 3 - the pleuroscopy in connection with the excision of material for cytological and histological tests. A therapeutical treatment is not known till now. Highly restricted use of asbestos is an imperative prophylactic measure.
D000328:Adult; D000368:Aged; D001194:Asbestos / Q000009:adverse effects; D004724:Endoscopy; D005260:Female; D005859:Germany, East; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D010996:Pleural Effusion / Q000209:etiology; D010997:Pleural Neoplasms / Q000139:chemically induced / Q000175:diagnosis* / Q000473:pathology; D011677:Punctures; D012131:Respiratory Insufficiency / Q000209:etiology
D001194:Asbestos
Atiologie und klinishce Diagnostik diffuser Pleuramesotheliome