title: [Mechanisms of catecholamine synthesis disorders in the adrenals of rats subjected to physical fatigue].
abstract: There was a depression of transformation of noradrenaline, DOPA and thyrosine added in vitro, into catecholamines in the adrenal glands of rats after swimming for a period of 8 hours. This permitted to suppose a depression of the activity of phenylethanolamine-N-methyl-transpherase, DOPA-decarboxylase, and, possibly, of tyrosine hydroxylase under these conditions. After the end of swimming, in the presence of 1-tyrosine, there is at first an activation of noradrenaline synthesis, and then there occurs a gradual normalization (on the 7th day) of adrenaline formation. In rats trained for a period of 2 months the extent of reduction of the catecholamine synthesis in the adrenal glands in response to the 8-hour swimming was much less in comparison with the untrained aniamals.
mesh_terms: D000311:Adrenal Glands / Q000378:metabolism*; D000818:Animals; D002395:Catecholamines / Q000096:biosynthesis*; D004298:Dopamine / Q000378:metabolism; D004837:Epinephrine / Q000096:biosynthesis; D005221:Fatigue / Q000378:metabolism*; D007980:Levodopa / Q000378:metabolism; D008297:Male; D009638:Norepinephrine / Q000096:biosynthesis; D051381:Rats; D014443:Tyrosine / Q000378:metabolism
chemical_list: D002395:Catecholamines; D014443:Tyrosine; D007980:Levodopa; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine
vernacular_title: Mekhanizmy narusheniia sinteza katekholaminov v nadpochechnikakh krys pri fizicheskom utomlenii