title: [Comparative study of immunity in swine vaccinated with foot-and-mouth disease vaccines prepared with various adjuvants].
abstract: The vaccines used were prepared with saponin, an oil adjuvant and a DEAE-dextran adjuvant. Comparative studies revealed that vaccines containing DEAE-dextran at the rate of 50 mg pro dosi confer weaker immunity as compared with vaccines containing saponin or an oil adjuvant. Pointed out is the lack of correlation between the antibody level in the vaccinated animals and the effectiveness of the immunity conferred, which was established through challenge. Discussed is the quality of the DEAE-dextran containing vaccine in comparison with the other two F. M. D. vaccines. The practical use of the oil containing vaccine is also discussed. Studies revealed that it confers the best immunity in the vaccinated pigs.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D005069:Evaluation Studies as Topic; D005536:Foot-and-Mouth Disease / Q000517:prevention & control*; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D013997:Time Factors; D014611:Vaccination / Q000662:veterinary*; D014765:Viral Vaccines / Q000592:standards*
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines
vernacular_title: Sravnitelni prouchvaniia na imuniteta pri svine, vaksinirani s protivoshapni vaksini, prigotveni s razlichni adzhuvanti