[Significance of the chemical structure and composition of blood substitutes in the genesis of posttransfusion reactions].
The work is concerned with an attempt to formulate grounds for the occurrence of possible posttransfusion reactions and complications as a result of transfusing blood substitutors from the group of synthetic and semisynthetic polymers, protein hydrolysates and aminoacid mixtures. Also, the classification of the reaction types, depending on ehc chemical structure and content of substitutors, is suggested. Some trends of prophylaxis against possible complications and reactions arising as a result of transfusion therapy are delineated, and certain demands are made to the content of new blood substitutors that would provide for a minimum risk in their application.
D000596:Amino Acids / Q000009:adverse effects; D004342:Drug Hypersensitivity / Q000628:therapy; D006801:Humans; D010952:Plasma Substitutes / Q000009:adverse effects*; D011108:Polymers / Q000009:adverse effects; D011492:Protein Hydrolysates / Q000009:adverse effects
D000596:Amino Acids; D010952:Plasma Substitutes; D011108:Polymers; D011492:Protein Hydrolysates
Znachenie khimicheskoĭ struktury i sostava krovezamiteleĭ v geneze posttranfuzionnykh reaktsiĭ