[Progresses in the preparation of protein hydrolysates for the treatment of diseases related to aminoacid metabolism disorders (author's transl)].
A method is described for the preparation of a protein hydrolysate to be used in diets for the treatment of the diseases primarily related to disorder of amino acid Metabolism. The method is based on the use of ion-exchange resins to avoid the use of mineral acids so that the time of hydrolysis is reduced to 7 hrs and aminoacids destroyed in the usual industrial preparations are protected. Yields of 70% are obtained with an hydrolysis ratio of 90%. These results allow the preparation of hydrolysates with a high chemical score in which the aminoacid responsible for the diseases primarily related to disorder of amino acid Metabolism symtoms have been removed.
D000592:Amino Acid Metabolism, Inborn Errors / Q000188:drug therapy*; D006801:Humans; D006868:Hydrolysis; D007475:Ion Exchange Resins; D011492:Protein Hydrolysates / Q000302:isolation & purification* / Q000627:therapeutic use
D007475:Ion Exchange Resins; D011492:Protein Hydrolysates
Progressi nella preparazione di idrolisati proteici per il trattamento delle oligofrenie dismetaboliche