[Idiopathic orthostatic hypotension (Shy-Drager syndrome). Results of regional cerebral blood flow measurements (author's transl)].
Using a gamma camera and the stochastic method, regional cerebral blood flow was measured in a patient with the diagnosis of idiopathic orthostatic hypotension. Blood pressure was altered by tilting the patient in supine position head-up and head-down. A partial defect in the autoregulation and CO2 sensitivity was found. Sensitivity to Norepinephrine was checked by intravenous infusion of 0.02 mug/min/kg body weight. An immediate marked rise in blood pressure was observed. Clinical symptoms, therapeutic guidelines, and histopathological findings are discussed.
D000328:Adult; D001794:Blood Pressure; D002560:Cerebrovascular Circulation / Q000187:drug effects; D006706:Homeostasis; D006801:Humans; D007024:Hypotension, Orthostatic / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D008297:Male; D009460:Neurologic Examination; D009638:Norepinephrine / Q000494:pharmacology; D011187:Posture; D013577:Syndrome
D009638:Norepinephrine
Idiopathische orthostatische Hypotension (Shy-Drager-Syndrom). Ergebnisse regionaler Hirndurchblutungsmessungen