[Neurophysiological mechanisms of the action of stimulators on the memory].
Aethimizol - and strychnine-induced improvement of the short-term memory in dogs is attened by a rising level of excitability of the mesencephalic reticular formation, ventral hippocampus and of the frontal region of the neocrotex. And, conversely, with the stimulats producing a facilitating effect on the memory the excitability of the dorsal hippocampus, mamillary bodies and the dorso-medial amygdala becomes less intensive. At the same time, the function of the anterio-ventral thalamus, basolateral amygdala and also of the primary visual and accoustic regions of the neocortex remains unchanged. Aethimizol exerts an inhibitory effect on the lateral and ventro-medial hypothalamus whereas strychnine raises the excitability of the later and does not change the function of the ventro-medial hypothalamus. The lack of stimulating effect of caffeine on the memory is due to a different organization of the brain.
D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000502:physiology; D002110:Caffeine / Q000494:pharmacology*; D004027:Diencephalon / Q000187:drug effects / Q000502:physiology; D004285:Dogs; D004567:Electrodes, Implanted; D005042:Etimizol / Q000494:pharmacology*; D007093:Imidazoles / Q000494:pharmacology*; D008570:Memory, Short-Term / Q000187:drug effects* / Q000502:physiology; D008636:Mesencephalon / Q000187:drug effects / Q000502:physiology; D013331:Strychnine / Q000494:pharmacology*
D007093:Imidazoles; D002110:Caffeine; D013331:Strychnine; D005042:Etimizol
Neĭrofiziologicheskie mekhanizmy deĭstviia stimuliatorov na pamiat'