[Treatment of hyperlipidaemia. A comparison of the efficacy of clofibrate and beta-pyridylcarbinol (author's transl)].
64 patients with hyperlipidaemia, 13 of them with pure hypercholesterolaemia, were assigned to one of three pre-determined treatment regimes over a period of seven months. Two different commercial preparations of clofibrate and one preparation of beta-pyridylcarbinol were each given for two months separated by placebo periods of two weeks. All three drugs were equally effective against increased cholesterol levels. The two clofibrate preparations lowered increased triglyceride levels more reliably than beta-pyridylcarbinol.
D002784:Cholesterol / Q000097:blood; D002994:Clofibrate / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy; D006949:Hyperlipidemias / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009540:Nicotinyl Alcohol / Q000627:therapeutic use*; D010919:Placebos; D011725:Pyridines / Q000627:therapeutic use*; D014280:Triglycerides / Q000097:blood
D010919:Placebos; D011725:Pyridines; D014280:Triglycerides; D002784:Cholesterol; D009540:Nicotinyl Alcohol; D002994:Clofibrate
Die Behandlung von Hyperlipidämien. Ein Vergleich der Wirksamkeit von Clofibrat und beta-Pyridylcarbinol