Erythropoietic restoring capacity of hematopoietic stem cells from liver of adult mice recovering from cyclophosphamide.
A comparison of the erythropoietic restoring capacity of colony-forming units (CFU) found in the liver of adult mice recovering from a single high dose of cyclophosphamide (CY) with that of CFU derived from fetal liver and from adult bone marrow and spleen was made. In this respect CFU in the liver of adult mice differ notably from CFU in fetal liver but have a striking similarity with adult splenic CFU.
D000818:Animals; D001853:Bone Marrow / Q000502:physiology; D001854:Bone Marrow Cells; D003520:Cyclophosphamide / Q000494:pharmacology*; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000502:physiology*; D004920:Erythropoiesis / Q000187:drug effects*; D005260:Female; D006412:Hematopoietic Stem Cells / Q000502:physiology*; D008099:Liver / Q000166:cytology / Q000502:physiology*; D051379:Mice; D013154:Spleen / Q000166:cytology
D003520:Cyclophosphamide