Central nervous system regeneration and ophthalmology.
Various adult lower vertebrates are capable of optic nerve, and even retinal, regeneration with functional recovery of vision. Possible factors responsible for regenerative failure in mammals are discussed. It is suggested that potentially neuroregenerative agents be tested in the mammalian retina in an attempt to induce visual pathway regeneration.
D000818:Animals; D001369:Axons; D002490:Central Nervous System / Q000503:physiopathology*; D004594:Electrophysiology; D005471:Fluoroscopy; D008322:Mammals; D009410:Nerve Degeneration; D009416:Nerve Regeneration; D009900:Optic Nerve / Q000503:physiopathology*; D012162:Retinal Degeneration / Q000188:drug therapy / Q000503:physiopathology*; D014714:Vertebrates; D014786:Vision Disorders / Q000628:therapy