The inhibition of DNA-dependent RNA sythesis in Yoshida ascites cells by bovine follicular fluid.
Follicular fluid aspirated from large cow follicles inhibits endogenous, DNA-dependent RNA polymerase activity in Yoshida ascites cells. The inhibitory component of follicular fluid is probably a protein and appears to affect specifically the activity of the nucleoplasmic polymerase II.
D000546:Amanitins / Q000494:pharmacology; D000818:Animals; D002417:Cattle; D002478:Cells, Cultured; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D005122:Exudates and Transudates; D005260:Female; D006358:Hot Temperature; D010053:Ovary; D010949:Plasma; D012313:RNA / Q000096:biosynthesis*
D000546:Amanitins; D012313:RNA; D012321:DNA-Directed RNA Polymerases