Tryptophan metabolism and recurrence rates of patients with breast cancer after mastectomy.
Women with early breast cancer were given a loading dose of L-tryptophan after mastectomy and a comparison made between their excretion of metabolites of the kynurenine pathway and the rate of recurrence of the disease.
D015065:17-Hydroxycorticosteroids / Q000652:urine; D015068:17-Ketosteroids / Q000652:urine; D000328:Adult; D000367:Age Factors; D000368:Aged; D001943:Breast Neoplasms / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007737:Kynurenine / Q000378:metabolism; D008408:Mastectomy; D008593:Menopause; D008875:Middle Aged; D013997:Time Factors; D014364:Tryptophan / Q000378:metabolism*
D015065:17-Hydroxycorticosteroids; D015068:17-Ketosteroids; D007737:Kynurenine; D014364:Tryptophan