[The effect of cysteamine on x-ray induction of mutations resulting in resistance to 8-azaguanine in Chinese hamster cells in vitro].
The survival of Chinese hamster cell was increased after the administration of cisteamine (at doses of 1,25; 2,5 and 5,0 mM/ml) in the culture for 15--20 min. before X-irradiation (600r). In the same experiment the protector decreased the rate of induced Ag-resistance gene mutations.
D000818:Animals; D001375:Azaguanine; D002999:Clone Cells; D006224:Cricetinae; D003543:Cysteamine / Q000494:pharmacology*; D004351:Drug Resistance; D009154:Mutation / Q000187:drug effects*; D011831:Radiation Genetics; D014965:X-Rays
D003543:Cysteamine; D001375:Azaguanine
Vliianie tsisteamina na induktsiiu rentgenovymi luchami mutatsiĭ rezistentnosti k 8-azaguaninu v kletkakh kitaĭskogo khomiachka in vitro