An investigation of the hepatotoxicity of D-galactosamine in different species of animal.
An examination of the hepatotoxicity of d-galactosamine has been made in the golden hamster and the mouse and the results compared to those previously investigated in the rat. The order of species found susceptible to the hepatotoxic effects of d-galactosamine was golden hamster greater than rat greater than mouse.
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology / Q000209:etiology*; D006224:Cricetinae; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D005688:Galactosamine / Q000008:administration & dosage / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008297:Male; D051379:Mice; D051381:Rats; D013045:Species Specificity; D013997:Time Factors
D005688:Galactosamine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase