[Experimental study of the anti-arrhythmia action of unithiol].
Tests conducted on 70 rabbits showed that cardiac rhythm disorders produced by introduction of a 10% calcium chloride solution was prevented by the administration of unithiol. With developing arrhythmia in the muscle of the rabbits' heart the level of sulfhydryl groups went down. The introduction of unithiol was followed by a rising content of sulfhydryl groups, especially in the myocardium of the left ventricle.
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D002122:Calcium Chloride / Q000494:pharmacology; D004112:Dimercaprol / Q000031:analogs & derivatives*; D004305:Dose-Response Relationship, Drug; D004562:Electrocardiography; D005260:Female; D008297:Male; D009206:Myocardium / Q000032:analysis; D011817:Rabbits; D013438:Sulfhydryl Compounds / Q000032:analysis; D014494:Unithiol / Q000494:pharmacology*
D000889:Anti-Arrhythmia Agents; D013438:Sulfhydryl Compounds; D004112:Dimercaprol; D014494:Unithiol; D002122:Calcium Chloride
Izuchenie antiaritmicheskogo deĭstviia unitiola v éksperimente