title: Cortical electrographic correlates of convulsive seizure development induced by daily electrical stimulation of the amygdala in rats and cats.
abstract: Increasing complexity of neocortical AD morphology was associated with clinical seizure development of amygdaloid origin in both rats and cats. Chronological examination of cortical AD and IID patterns in cats suggests very early involvement of basal cortical areas. Delayed but progressive ictal participation of anterior neocortical areas with eventual development of IID was coincident with eventual development of IID was coincident with recruitment of ictal motor manifestations while neocortical asymmetry with contralateral "desynchronization" pattern persisted throughout seizure development. It is suggested that anterior neocortex participates in the clinical expression of seizure development while verticle ictal propagation into the brain stem is responsible for seizure generalization.
mesh_terms: D000679:Amygdala / Q000502:physiology*; D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000503:physiopathology*; D004558:Electric Stimulation; D004569:Electroencephalography; D008297:Male; D051381:Rats; D012154:Reticular Formation / Q000503:physiopathology; D012640:Seizures / Q000503:physiopathology*