[Amyloidosis in familial mediterranean fever: clinical and renal-biopsy features (author's transl)].
In two Turkish female patients, aged 14 and 29 years, with familial mediterranean fever amyloidosis of the perireticular type was found. The disease was characterized by feverish bouts, abdominal colics, and joint involvements. The younger patient had the diagnosis confirmed at an early stage by renal biopsy, and under heparin and azathioprine the clinical signs, especially the nephrotic syndrome, regressed over a period of seven months. The second patient died of treatment-resistant shock in acute renal failure, due to rapidly progressing renal amyloidosis.
D058186:Acute Kidney Injury / Q000150:complications; D000293:Adolescent; D000328:Adult; D000686:Amyloidosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D001379:Azathioprine / Q000627:therapeutic use; D001706:Biopsy; D010505:Familial Mediterranean Fever / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007668:Kidney / Q000473:pathology; D009404:Nephrotic Syndrome / Q000150:complications / Q000188:drug therapy; D012769:Shock / Q000150:complications
D006493:Heparin; D001379:Azathioprine
Amyloidose bei familiärem Mittelmeerfieber. Klinische und nierenbioptische Beobachtungen