title: DNA replication patterns of the early S phase from amniotic fluid cells as revealed by a Giemsa staining technique.
abstract: We report on DNA replication patterns of the early S phase demonstrated by a BUdR/Hoechst (33258)-fluorescence/Giemsa technique. Replication starts in R bands and spreads within 1 hr over the whole chromosome complement with exceptions concerning heterochromatin. The beginning and the duration of replication are discussed.
mesh_terms: D000653:Amniotic Fluid / Q000166:cytology; D001399:Azure Stains; D001973:Bromodeoxyuridine / Q000378:metabolism; D002875:Chromosomes / Q000378:metabolism* / Q000648:ultrastructure; D004261:DNA Replication; D008938:Mitosis; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors
chemical_list: D001399:Azure Stains; D001973:Bromodeoxyuridine; D013936:Thymidine