title: Split-hand and split-foot deformity inherited as an autosomal recessive trait.
abstract: A intermarried consanguineous family with split-hand and -foot deformity occurring in two sibship is presented. Both the sibship resulted from marriage between first cousins. This report, together with those of Ray (1960) and Freire-Maia (1971), further demonstrates that split-hand and -foot deformity can be inherited as an autosomal recessive trait.
mesh_terms: D000015:Abnormalities, Multiple; D002675:Child, Preschool; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D003241:Consanguinity; D005528:Foot / Q000000981:diagnostic imaging; D005532:Foot Deformities, Congenital; D005542:Forearm / Q000000981:diagnostic imaging; D006228:Hand Deformities, Congenital; D006801:Humans; D008297:Male; D010375:Pedigree; D011859:Radiography