title: Effects of estrus and exogenous estrogen on circulating neutrophils and milk somatic cell concentration, neutrophil phagocytosis, and occurrence of clinical mastitis in cows.
abstract: In a study involving 56 quarters (14 cows), it was seen that standing estrus did not affect circulating neutrophil and milk somatic cell concentrations, neutrophil phagocytosis, milk production, or occurrence of clinical mastitis. The subcutaneous injection of 17beta-estradiol (E2) (0.05 mg/kg of body weight 2 times daily for 2 consecutive days) did not affect neutrophil phagocytosis or milk somatic cell values. However, a significant increase in circulating neutrophils and a significant decrease in milk production were observed. The injection of E2 was followed by clinical mastitis in 4 uninfected quarters, in 7 quarters infected with Corynebacterium bovis, and in 1 quarter infected with Streptococcus uberis and Escherichia coli.
mesh_terms: D000818:Animals; D002417:Cattle; D004958:Estradiol / Q000494:pharmacology*; D004971:Estrus; D005260:Female; D007774:Lactation; D007962:Leukocytes / Q000166:cytology; D008414:Mastitis, Bovine / Q000453:epidemiology* / Q000503:physiopathology; D008892:Milk / Q000166:cytology*; D009504:Neutrophils / Q000166:cytology* / Q000502:physiology; D010587:Phagocytosis; D011247:Pregnancy
chemical_list: D004958:Estradiol