title: [The effect of asphyxia on the electrical and mechanical activities of the rat hindlimb muscles (author's transl)].
abstract: After asphyxia by clamping external iliac artery, the changes of electrical and mechanical activities of M. extensor digitorum longus and soleus were followed up. Although the action potential amplitude was decreased monotonously, a transient increase in twitch tension appeared, one or two minutes after start of asphyxia, which was seen more frequently and more remarkable in extensor than soleus. This was attributed to the different metabolic process of components contained in the muscle and also to their different population in two kinds of muscle fibres. It was suggested from the previous results obtained by us that the decrease of action potential amplitude, at least in the early period of asphyxia, was not due to membrane depolarization but to conformational change of Na-channel by anoxia.
mesh_terms: D000200:Action Potentials; D000818:Animals; D005399:Fishes; D066298:In Vitro Techniques; D007511:Ischemia; D008297:Male; D009119:Muscle Contraction; D009132:Muscles / Q000098:blood supply / Q000502:physiology*; D010100:Oxygen; D051381:Rats
chemical_list: D010100:Oxygen