Effect of prolonged administration of L-leucine-4-anti-pyrineamide dihydrochloride on certain organs and blood formation system in rat.
Newly synthesized L-leucine-4-antipyrineamide shows the biological effect of aminopyrine. In contrast, it does not cause any adverse effect on the growth of rat, and induces neither degeneration of the parenchymal organs nor agranulocytosis.
D000380:Agranulocytosis / Q000139:chemically induced; D000632:Aminopyrine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D000818:Animals; D007930:Leucine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D008297:Male; D051381:Rats
D000632:Aminopyrine; D007930:Leucine