title: Effect of intra-articular 90Y resin treatment on the chemical properties of synovial fluid in rheumatoid arthritis.
abstract: Lyaluronic acid and total protein concentrations in synovial fluid of the knee joint obtained from 48 patients with classical or definite rheumatoid arthritis were determined before, and 1 week, 1 month and 6 months after intra-articular injection of 90Y resin colloid. The concentration ratio of total protein to hyaluronic acid, which is a sensitive index of the abnormality of the synovial fluid, was worse a week after the injection in each group as regards the clinical effect of the 90Y resin injection, but was better 1 month and 6 months after the injection only in the remission group.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001172:Arthritis, Rheumatoid / Q000378:metabolism* / Q000532:radiotherapy; D002642:Chick Embryo; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006820:Hyaluronic Acid / Q000032:analysis; D007270:Injections, Intra-Articular; D008297:Male; D011506:Proteins / Q000032:analysis; D012075:Remission, Spontaneous; D012116:Resins, Plant / Q000494:pharmacology / Q000627:therapeutic use; D013582:Synovial Fluid / Q000032:analysis*; D013997:Time Factors; D015021:Yttrium Radioisotopes / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D011506:Proteins; D012116:Resins, Plant; D015021:Yttrium Radioisotopes; D006820:Hyaluronic Acid