Systemic copper and sex steroids uptake by rat tissues.
Subcutaneous injection of copper sulphate into the rat produced a significant depression in the relative and absolute uptake of oestradiol by the uterus. With progesterone, an enhancement in the absolute count uptake in the uterus, muscle, liver and kidney occurred. The absolute uptake of oestradiol in muscle, liver and kidney were also enhanced.
D000818:Animals; D003300:Copper / Q000494:pharmacology*; D004958:Estradiol / Q000378:metabolism*; D005260:Female; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D011374:Progesterone / Q000378:metabolism*; D051381:Rats; D014599:Uterus / Q000378:metabolism
D011374:Progesterone; D004958:Estradiol; D003300:Copper