[Quantitative and qualitative changes in the sex chromatin of diabetic women of different ages].
There was revealed a statistically significant reduction in the frequency of occurrence of sex chromatine (SC) in the patients (female) suffering from diabetes mellitus aged from 15 to 65 years before the treatment in comparison with the healthy women. After the compensation of the carbohydrate metabolism there was noted its further reduction in the patients aged from 25 to 65 years. In 15-65-year women who contracted diabetes mellitus there was an increase in the circular form of the SC bodies looking like thickenings of the nuclear membrane; SC bodies of round shape enlarged as well in women aged from 25 to 65 years. Oval, triangular and semicircular forms decreased in all the age groups. After the compensation of the carbohydrate metabolism the content of the SC bodies of various shapes remained the same as at the beginning of the disease without returning to the normal level. The area of the SC bodies enlargement was statistically significant in women who fell ill with diabetes mellitus.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D003920:Diabetes Mellitus / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D012728:Sex Chromatin / Q000648:ultrastructure
Kolichestvennye i kachestvennye izmeneniia polovogo khromatina u bol'nykh sakharnym diabetom zhenshchin raznogo vozrasta