title: [Neuroblastoma in children. Anatomoclinical study of 46 cases].
abstract: The authors stress the difficulty of diagnosis of a neuroblastoma in its undifferentiated when the demonstration of nervous differentiation is necessary. The factors which may play a role in the prognosis of these tumours are analysed. In this series are included the age of the child, the location of the tumour, the existence of certain early metastases (bone), the possibility of complete surgical removal and alterations in the tumour secondary to chemotherapy and radiotherapy. Histoenzymatic study of histio and organotypic cultures as well as chromosomal analysis were possible in a number of cases.
mesh_terms: D000008:Abdominal Neoplasms / Q000473:pathology; D000367:Age Factors; D002675:Child, Preschool; D003593:Cytoplasm / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009362:Neoplasm Metastasis; D009447:Neuroblastoma / Q000150:complications / Q000401:mortality / Q000473:pathology*; D009474:Neurons / Q000648:ultrastructure; D011379:Prognosis; D012737:Sex Factors; D013899:Thoracic Neoplasms / Q000473:pathology
vernacular_title: Les neuroblastomes de l'enfant. Etude anatomo-clinique de 46 observations