title: Dietary regulation of serum lipids in healthy, young adults.
abstract: When healthy medical students and their wives were fed a diet providing 2,375 kcal per day, 33 per cent of which was derived from fat, and received a cholesterol intake of less than 250 mg. per day, their serum cholesterol levels were significantly reduced. Differences in the change in the phospholipids of the students and their wives suggest a different response of the sexes to the diet. Since increasing the P:S ratio from 0.3 to 1.2 produced comparable lowering of serum lipids, data suggest that cholesterol intake and caloric balance are of prime importance in maintaining the level of serum cholesterol.
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000097:blood*; D002791:Cholesterol, Dietary; D004041:Dietary Fats; D004734:Energy Metabolism; D005224:Fats, Unsaturated / Q000494:pharmacology; D005227:Fatty Acids / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D010743:Phospholipids / Q000097:blood*; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood*
chemical_list: D002791:Cholesterol, Dietary; D004041:Dietary Fats; D005224:Fats, Unsaturated; D005227:Fatty Acids; D010743:Phospholipids; D014280:Triglycerides; D002784:Cholesterol