title: Atherosclerotic occlusions in anomalous left circumflex coronary arteries. A report of two unusual cases & a review of pertinent literature.
abstract: Two cases of atherosclerotic occlusion of anomalous left circumflex coronary arteries having origin from a common ostium with the left coronary artery are documented. The atheromatous lesion was found at the same site in each case, i.e. the junction of the segment bound to the posterior wall of the aorta and its freer course in the atrioventricular sulcus. It appears that these junctions have an increased susceptibility to atherosclerotic changes, to local hemodynamic factors and local trauma related to the sudden change from a fixed artery to one lying relatively unfixed in the fibro-fatty tissue of the atrioventricular sulcus.
mesh_terms: D003327:Coronary Disease / Q000209:etiology* / Q000473:pathology; D003330:Coronary Vessel Anomalies / Q000150:complications* / Q000473:pathology; D003331:Coronary Vessels / Q000473:pathology; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged