[Importance of digitalemia for a correct therapeutic attitude using cardioactive glycosides].
Recent advances in the quantitation of plasma or serum levels of cardiac glycosides promise to add a new dimension to pharmacologic studies and to the evaluation of clinical problems involving these drugs. A rapid radioimmunoassay technique has been described for the determination of serum digoxin and beta-metyldigoxin concentration in the range encountered clinically. Patients judged clinically to show digitals toxicity in general had higher levels. A relable estimate of serum digoxin and beta-metyldigoxin concentration, considered in the clinical context, has been found to be useful in arriving at acute management decisions.
D000284:Administration, Oral; D001711:Biotransformation; D002301:Cardiac Glycosides / Q000097:blood* / Q000627:therapeutic use; D004077:Digoxin / Q000008:administration & dosage / Q000097:blood; D006801:Humans; D007457:Iodine Radioisotopes; D011863:Radioimmunoassay
D002301:Cardiac Glycosides; D007457:Iodine Radioisotopes; D004077:Digoxin
Importanza della digitalemia per una corretta impostazione terapeutica con i glucosidi cardioattivi