title: Rapid micromethod for blood lead analysis by anodic stripping voltammetry.
abstract: We describe a rapid microscale procedure for blood lead determination by anodic stripping voltammetry. Results correlate well with those obtained by atomic absorption spectroscopy. The procedure involves use of a metal-exchange reagent, which rapidly releases bound lead from its macromolecular binding sites, thus eliminating a long and cumbersome perchloric acid digestion procedure. Reproducibility and analytical recovery of added lead were both excellent. Our results show that anodic stripping voltammetry is a reliable, sensitive micromethod for routine determination of blood lead.
mesh_terms: D001665:Binding Sites; D005069:Evaluation Studies as Topic; D006801:Humans; D007854:Lead / Q000097:blood*; D046911:Macromolecular Substances; D008403:Mass Screening; D008832:Microchemistry; D011199:Potentiometry; D011786:Quality Control; D013054:Spectrophotometry, Atomic
chemical_list: D046911:Macromolecular Substances; D007854:Lead