title: [Study of the changes in serum enzyme activity in acute phenol poisoning].
abstract: The activity of some serum enzymes is followed up under conditions of acute phenol intoxication. Analysis is made in dynamics within 2, 12 and 24 hours after toxic substance administration. An increase in the activity of the parenchyma non-specific enzymes SChE, LDH and LAP is noted. No changes are established in the activity of Al.Ph. The hyperfermentemia present is most likely attributable to disturbed cellular membrane permeability and cell destruction.
mesh_terms: D000208:Acute Disease; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D002802:Cholinesterases / Q000097:blood; D004789:Enzyme Activation / Q000187:drug effects; D004798:Enzymes / Q000097:blood*; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007931:Leucyl Aminopeptidase / Q000097:blood; D010636:Phenols / Q000506:poisoning*; D011041:Poisoning / Q000201:enzymology; D011817:Rabbits; D013997:Time Factors
chemical_list: D004798:Enzymes; D010636:Phenols; D007770:L-Lactate Dehydrogenase; D002802:Cholinesterases; D000469:Alkaline Phosphatase; D007931:Leucyl Aminopeptidase
vernacular_title: Proslediavane promianata v aktivnostta na niakoi serumni enzimi pri ostra fenolova intoksikatsiia.