title: [The effect of functional overstrain of the central nervous system and endocrine disorders on the development of experimental atherosclerosis in dogs].
abstract: In a chronic experiment (up to 6 years) on dogs (13) a protracted functional overstrain of the CNS was associated with an additional action changing the hormonal background (castration and mercasolyl injection). A steady hypercholesteremia, atherosclerotic changes in different intraorganic arteries, particularly in the myocardium, developed in dogs; dystrophic processes occurred in the parenchyma of various organs. An important role of functional overstrain of the CNS as one of the leading factors of the "risk" determining the development of disturbances of the regulation of lipid metabolism and formation of the atherosclerotic process in the vessels was demonstrated.
mesh_terms: D000818:Animals; D001158:Arteries / Q000473:pathology; D001161:Arteriosclerosis / Q000150:complications / Q000209:etiology* / Q000473:pathology; D002369:Castration / Q000009:adverse effects*; D004285:Dogs; D006937:Hypercholesterolemia / Q000150:complications / Q000209:etiology*; D007037:Hypothyroidism / Q000150:complications*; D008297:Male; D013312:Stress, Physiological / Q000150:complications*
vernacular_title: Vliianie funktsional'nogo perenapriazheniia tsentral'noĭ nervnoĭ sistemy i éndokrinnykh narusheniĭ na razvitie éksperimental'nogo ateroskleroza u sobak