[Study of some oxidoreductases in nerve tissue culture].
A change in the activity of succinic dehydrogenase, of the NAD- and NADP-diaphorases was studied in the dissociated culture of the cerebellum of neonatal rats under the effect of immune serum of the animals with an experimental allergic pertussis encephalomyelitis. There was revealed an increase in the activity of oligodendrocytes following a 3-hour exposure with the immune serum and a reduction of the activity of the enzymes under study in the same cells after a 12-hour exposure of the cultures with the serum. In difference from oligodendrocytes, the astrocytes displayed a high activity of all the enzymes under study after a 12-hour exposure.
D000818:Animals; D000831:Animals, Newborn; D002531:Cerebellum / Q000201:enzymology* / Q000276:immunology; D002952:Citric Acid Cycle; D046508:Culture Techniques; D008058:Dihydrolipoamide Dehydrogenase / Q000378:metabolism; D004579:Electron Transport / Q000187:drug effects; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology; D004789:Enzyme Activation / Q000187:drug effects; D006168:Guinea Pigs; D007106:Immune Sera / Q000494:pharmacology; D009252:NADPH Dehydrogenase / Q000378:metabolism; D010088:Oxidoreductases / Q000276:immunology / Q000378:metabolism*; D051381:Rats; D013385:Succinate Dehydrogenase / Q000378:metabolism; D013997:Time Factors
D007106:Immune Sera; D010088:Oxidoreductases; D013385:Succinate Dehydrogenase; D009252:NADPH Dehydrogenase; D008058:Dihydrolipoamide Dehydrogenase
Izuchenie nekotorykh okislitel'no-vosstanovitel'nykh fermentov v kul'ture nervnoĭ tkani