Localization of dopamine in the endocrine hypothalamus of the rat.
Microspectrofluorometry, fluorescence histochemistry and light and electron microscopic autoradiography have established the presence of sub-populations of neurons in the arcuate-periventricular region of the rat hypothalamus that sequester both radiolabeled dopamine and demonstrate formaldehyde-induced fluorescence. These characteristics are consistent with a catecholaminergic function. Selective sequestration of 3H-dopamine at the light and ultrastructural level is discussed in the context of an ultrashort loop autoregulatory mechanism for this neuronal population.
D000818:Animals; D001345:Autoradiography; D004298:Dopamine / Q000032:analysis* / Q000378:metabolism; D004805:Ependyma / Q000032:analysis; D007031:Hypothalamus / Q000032:analysis* / Q000378:metabolism / Q000648:ultrastructure; D007032:Hypothalamus, Anterior / Q000032:analysis; D008297:Male; D008473:Median Eminence / Q000032:analysis; D008856:Microscopy, Fluorescence; D009474:Neurons / Q000032:analysis; D009638:Norepinephrine / Q000032:analysis; D009940:Organoids / Q000032:analysis; D051381:Rats; D012701:Serotonin / Q000032:analysis
D012701:Serotonin; D004298:Dopamine; D009638:Norepinephrine