Updating the maximization test for identifying contact allergens.
The maximization test for detecting contact allergens has proved to possess both sensitivity and specificity. However, modifications have become necessary because of excessive irritancy reactions to sodium lauryl sulfate. Fewer exposures are now recommended during induction and lower concentrations for challenge patch testing. Pre-testing of each subject in the panel is now standard procedure. The problem of interpreting challenge patch tests is discussed in detail.
D000485:Allergens; D003877:Dermatitis, Contact / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008722:Methods; D010328:Patch Tests; D012621:Seasons
D000485:Allergens