Use of the electrocardiogram as an aid in screening for left ventricular aneurysm.
Attempting to cull from a population of patients with coronary artery disease or cardiomyopathy, a subgroup in whom left ventriculography might most reasonably be performed in search of a surgically resectable ventricular aneurysm, the electrocardiograms (ECGs) and ventriculograms of 96 patients were analyzed. This study was conceived to test the value of the ECG as an initial screening technique. Patients with normal ventricular contractile motion in the presence of coronary artery disease rarely showed ST segment elevation exceeding 2 mm in any lead, and even more rarely showed Q waves in corresponding leads. All patients with well defined left ventricular aneurysms had at least 1 mm ST segment elevation, and the majority (73%) had ST elevation of 2 mm or greater; in 80% of these, there were associated Q waves in the same lead. In patients with only local areas of hypocontractility, the frequency of ST segment elevation with concomitant Q waves was significantly less (approximately 50%) than that seen in patients with aneurysms. It is concluded that patients with suspected or proven coronary disease who fail to demonstrate ST segment elevation are unlikely to have ventricular aneurysms and, thus, would receive little diagnostic benefit from left ventriculography. The presence of ST segment elevation, with or without associated Q waves in the same leads, is a helpful screening sign, raising the possibility of a surgically remediable lesion such as a ventricular aneurysm, but similar electrocardiographic patterns are also seen in patients with non-operable localized or generalized disorders of contraction. Having discovered ST elevation, then, left ventriculography becomes a reasonable next step - when otherwise indicated - in delineating the type of contractile disorder as well as the amount of adequately functioning muscle.
D000200:Action Potentials; D000790:Angiocardiography / Q000379:methods; D002932:Cineangiography; D003327:Coronary Disease / Q000503:physiopathology; D004562:Electrocardiography; D006322:Heart Aneurysm / Q000175:diagnosis* / Q000503:physiopathology; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D009200:Myocardial Contraction