title: [Cytogenetic studies of preinvasive lesions and invasive carcinomas of the cervix uteri. II. Structural chromosome abnormalities. Karyotype deviations (author's transl)].
abstract: An analysis of karyotypes was possible in 17 preinvasive lesions (3 dysplasias, 14 carcinomas in situ) and 15 invasive lesions of the cervix uteri (3 carcinomas in situ with microinvasion, 12 invasive squamos carcinomas - at least clinical stage I b). With regard to the structural chromosome abnormalities or karyotype deviations in this study the preinvasive lesions analysed could not be differentiated in principle as a group from the invasive lesions. The question of whether the dysplasia group would be different on further investigation with more cases and could be differentiated like the numerical deviations cannot yet be answered, because of the small numbers, only preinvasive lesions and invasive lesions could be studied comparatively as groups.
mesh_terms: D000328:Adult; D000368:Aged; D000782:Aneuploidy; D002278:Carcinoma in Situ / Q000235:genetics; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D011230:Precancerous Conditions / Q000235:genetics; D002583:Uterine Cervical Neoplasms / Q000235:genetics*
vernacular_title: Cytogenetische Untersuchungen an Praecancerosen und Carcinomen der Cervix uteri. II. Strukturelle chromosomenanomalien. Veränderungen im Karyotypus