The Marfan syndrome and pregnancy.
The patient described had the Marfan syndrome complicated by a 22-week pregnancy. Because pregnancy potentiates the cardiovascular complications of aortic aneurysm or dissection and there is a 50% risk of having a child afflicted with the disorder, this pregnancy was electively terminated by hysterotomy along with a bilateral tubal ligation. The risks of pregnancy to a woman with the Marfan syndrome are reviewed. The rationale for the method of pregnancy termination chosen is discussed.
D000032:Abortion, Therapeutic; D000328:Adult; D001014:Aortic Aneurysm / Q000209:etiology; D005260:Female; D006801:Humans; D008382:Marfan Syndrome / Q000150:complications; D011247:Pregnancy; D011248:Pregnancy Complications; D011262:Pregnancy Trimester, Second; D012422:Rupture, Spontaneous; D013246:Sterilization, Tubal; D014599:Uterus / Q000601:surgery