title: [Diurnal variations and the effect of cold exposure on the tissue histamine content in the rat (author's transl)].
abstract: Diurnal variations and the effect of cold exposure on histamine content in the liver, pinna and interscapular brown adipose tissue were investigated in the rat. A significant circadian rhythm of the histamine content was observed in the pinna and liver. In these tissues the content showed the peak at 5:00 a.m. and was maintained at low levels during the daytime. No significant variation was seen in the histamine content of brown adipose tissue. Acute cold exposure at -10 degrees C for 60 min caused an increase in the histamine content of the liver, while in the other two tissues the content was not affected by the cold exposure. Chronic cold exposure at 5 degrees C for 2 weeks caused a marked increase in the histamine content in brown adipose tissue and a moderate increase in the liver, while the content decreased in the pinna.
mesh_terms: D002001:Adipose Tissue, Brown / Q000378:metabolism; D000818:Animals; D002940:Circadian Rhythm; D003080:Cold Temperature; D004431:Ear, External / Q000378:metabolism; D006632:Histamine / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008297:Male; D051381:Rats
chemical_list: D006632:Histamine