Glucose transport in the short loop of Henle of the rat kidney. Its characterisation by transport constants.
Short loops of Henle in rat kidneys were perfused with proximal tubular equilibrium solutions containing radioactive D-glucose. The transport rates follow 2-parameter kinetics: Km = 5.7 mmol/I. Vmax - 145 X 10(-12) MOL/MIN-1; Phlorrhizin inhibits transport almost completely, indicating little passive diffusion of D-glucose. The glucose transport capacity in the short loops of Henle, presumably in the pars rects, is much smaller than that in superficial segments.
D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D004058:Diffusion; D005260:Female; D005947:Glucose / Q000037:antagonists & inhibitors / Q000378:metabolism*; D007684:Kidney Tubules / Q000378:metabolism*; D008138:Loop of Henle / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010695:Phlorhizin / Q000494:pharmacology; D051381:Rats / Q000378:metabolism*
D010695:Phlorhizin; D005947:Glucose