The value of premedication in diminishing salivary secretions.
A study has been carried out on the anti-sialogogue effect of some drugs used in premedication. Among different anaesthetic agents used in this study halothane appeared to be the least effective in stimulating salivary secretions. Pethidine-atropine combination proved to be very satisfactory as an anti-sialogogue. Atropine came next, where its intravenous route of administration was more satisfactory in short procedures than its intramuscular route.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001285:Atropine / Q000494:pharmacology*; D002744:Chlorpheniramine / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D008614:Meperidine / Q000494:pharmacology*; D008875:Middle Aged; D009609:Nitrous Oxide / Q000008:administration & dosage; D011229:Preanesthetic Medication; D012463:Saliva; D012472:Salivation / Q000187:drug effects*
D002744:Chlorpheniramine; D001285:Atropine; D008614:Meperidine; D009609:Nitrous Oxide