Studies on the species, amount and base composition of nucleic acids in psoriatic scales and normal horny layer.
The amount of RNA as well as DNA is considerably increased in psoriatic scales as compared with normal horny layer; RNA was characterized as a low-molecular tRNA; as concerns the base composition of DNA, no particularities in comparison with other DNA species were found, and the base composition of tRNA revealed that cytosine and guanosine are in excess; pseudouridine could not be detected in psoriatic tRNA.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002845:Chromatography; D004247:DNA / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D006868:Hydrolysis; D008875:Middle Aged; D009705:Nucleosides / Q000032:analysis; D010783:Photometry; D011565:Psoriasis / Q000378:metabolism*; D012343:RNA, Transfer / Q000032:analysis / Q000378:metabolism*; D012867:Skin / Q000378:metabolism*
D009705:Nucleosides; D004247:DNA; D012343:RNA, Transfer