Metastasizing tumors from serum-supplemented and serum-free cell lines from a C57BL mouse lung tumor.
A tissue culture cell line was established from an alveologenic lung carcinoma from a C57BL/lcrf-at mouse. The cells can be maintained in a completely defined serum-free medium. Tumors derived from the tissue culture cells grown in serum-free or serum-supplemented medium give rise to lung metastases. The ultrastructure of the tissue culture cells in both media is similar to that of spontaneous or induced alveologenic mouse lung tumors.
D000818:Animals; D002291:Carcinoma, Papillary / Q000473:pathology*; D002460:Cell Line; D003470:Culture Media; D046508:Culture Techniques; D051379:Mice; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron; D009362:Neoplasm Metastasis / Q000473:pathology*; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000209:etiology / Q000473:pathology
D003470:Culture Media