An investigation in rats, into the metabolic consequences of early ingestion of dietary carbohydrates.
Weanling rats were given diets containing a high proportion of either glucose, sucrose or fructose until they reached 200 g weight, when they were either transferred to a control (chow) diet for 4 weeks or killed. The results were compared with rats receiving a control diet throughout. The triglyceride (TG) and cholesterol levels in liver and in serum had returned to values similar to the control animals 4 weeks after being given the control diet. The fatty acid profile of liver TG and adipose lipid tended to take longer to return to normal.
D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D002784:Cholesterol / Q000097:blood / Q000378:metabolism; D004040:Dietary Carbohydrates; D005632:Fructose / Q000494:pharmacology*; D005947:Glucose / Q000494:pharmacology*; D006128:Growth / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D051381:Rats; D013395:Sucrose / Q000494:pharmacology*; D014280:Triglycerides / Q000097:blood / Q000378:metabolism
D004040:Dietary Carbohydrates; D014280:Triglycerides; D005632:Fructose; D013395:Sucrose; D002784:Cholesterol; D005947:Glucose