[The nature of differences in beta-adrenergic receptors].
Results of investigation of the affinity between teranol (practalol), alpheprol (alprenolol), propranolol to beta-adrenoreceptors of various organs confirmed the division of these receptors into two subtypes. The action of isadrin on beta1-adrenoreceptors of the myocardium and smooth muscles of the gastrointestinal tract was accompanied by changes in Ca2+ entrance into the cells. With the action of isadrin on beta2-adrenoreceptors of the trachea and the vessels there was seen an intensification of the Ca2+ ions from the cells and a reduction of the smooth muscle tone.
D000526:Alprenolol / Q000494:pharmacology; D000818:Animals; D002339:Carotid Arteries; D006168:Guinea Pigs; D006321:Heart / Q000294:innervation; D007545:Isoproterenol / Q000494:pharmacology; D009130:Muscle, Smooth / Q000294:innervation; D011217:Practolol / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects*; D013270:Stomach / Q000294:innervation; D014132:Trachea / Q000294:innervation
D011941:Receptors, Adrenergic; D000526:Alprenolol; D011433:Propranolol; D007545:Isoproterenol; D011217:Practolol
Issledovanie prirody razlichiî beta-adrenergicheskikh retseptorov