Plasma galactocerebrosides in multiple sclerosis.
Plasma cerebrosides were examined in 12 cases of multiple sclerosis which were compared to normal controls and patients with cerebrovascular accidents. A screening was performed so as to select patients with levels above to normal by means of thin-layer chromatography of the lipid extract. Glucose seems to be the only hexose to be found normally in plasma cerebrosides. The presence of galactocerebrosides may be a biological test for demyelination, as their presence seems to be related to the evolutionary state of multiple sclerosis. In a severe cerebrovascular accident, galactocerebrosides were also found.
D000328:Adult; D002554:Cerebrosides / Q000097:blood*; D002561:Cerebrovascular Disorders / Q000097:blood*; D005260:Female; D005690:Galactose / Q000032:analysis*; D005947:Glucose / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000097:blood*
D002554:Cerebrosides; D005947:Glucose; D005690:Galactose