[The effect of acetylsalicylic acid on the development of infarct-like myocardial necroses experimentally induced in rats by a single administration of novodrin (isopropylnoreadrenaline)].
It appeared that acetylsalicylic acid considerably decreased both development of the infarction-like foci of necrosis and primary damage of the myocardial cells experimentally induced in animals by direct action of novodrin and expressed in the course of the first hour. This led to the supposition that acetylsalicylic acid not only prevented platelet aggregation, but also increased the resistance of the myocardial cells to the injurious action of catecholamines.
D000818:Animals; D001241:Aspirin / Q000627:therapeutic use*; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced / Q000517:prevention & control*; D009336:Necrosis; D009638:Norepinephrine / Q000031:analogs & derivatives*; D051381:Rats
D001241:Aspirin; D009638:Norepinephrine
Vliianie atsetilsalitsilovoĭ kisloty na razvitie infarktopodobnykh nekrozov miokarda, vyzyvaemykh v éksperimente na krysakh odnokratnym vvedeniem novodrina (izopropilnoreadrenalina)