Benzo (a) pyrene uptake by normal and by tumour cells in vitro.
A method for determining the quantitative uptake of benzo(a)pyrene/B(a)P/by cells in culture is described. B(a)P uptake is very rapid and increases with concentration. The amount of B(a)P taken up by normal or by tumour cells depends on the cell type, and also, on the species from which they were derived.
D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism*; D002463:Cell Membrane Permeability; D002471:Cell Transformation, Neoplastic; D006224:Cricetinae; D046508:Culture Techniques; D005347:Fibroblasts / Q000378:metabolism; D005354:Fibrosarcoma / Q000378:metabolism; D008214:Lymphocytes / Q000378:metabolism; D008228:Lymphoma, Non-Hodgkin / Q000378:metabolism; D051379:Mice; D009374:Neoplasms, Experimental / Q000378:metabolism*; D011817:Rabbits; D051381:Rats
D001580:Benzopyrenes