title: Lactate dehydrogenase in preimplantation rabbit embryos.
abstract: Unfertilized eggs and early embryos up to the 2-day (16-cell) cleavage stage of development in the rabbit contain predominantly the most cathodal lactate dehydrogenase isoenzyme made up of A-type subunits. Following early cleavage there is a progressing increase in total LDH activity in the embryo as development proceeds through 4- and 6-day blastocyst stages. This is accompanied by an increase in the amount of B-type subunits and a concomitant shift in the lactate dehydrogenase isoenzyme electrophoretic pattern toward the anodal isoenzyme types.
mesh_terms: D000818:Animals; D001755:Blastocyst / Q000201:enzymology; D004622:Embryo, Mammalian / Q000201:enzymology; D047108:Embryonic Development; D005260:Female; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D009132:Muscles / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D010063:Ovum / Q000201:enzymology; D011247:Pregnancy; D011817:Rabbits; D013997:Time Factors
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase