[Lymphocyte sensibilisation by fetal antigens in man after immunisation with xenogeneic fetal cells and with malignant tumors (author's transl)].
Specific lymphocyte sensibilisation in man can be shown one to four months after injection of xenogeneic fetal cells by means of in vitro lymphocyte stimulation by the previous injected lyophilised fetal antigens. Adult lyophilised xenogeneic cells demonstrate no stimulatory effect. In the same test positive lymphocyte stimulation against lyophilised fetal cells can be demonstrated in about 50% of a group of patients with malignant tumors. These preliminary findings could be a possible link in evaluating the effects of fetal cells as a form of tumor-immunotherapy in man.
D000328:Adult; D000368:Aged; D000951:Antigens, Neoplasm; D005260:Female; D005333:Fetus / Q000166:cytology / Q000276:immunology*; D006801:Humans; D007114:Immunization; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000276:immunology; D013997:Time Factors
D000951:Antigens, Neoplasm
Lymphocytensensibilisierung gegen fetale Antigene bei Patienten nach Immunisierung mit fetalen Zellen und mit malignen Tumoren