Carcinogenic effects of niridazole.
Swiss mice received chronic treatment with the schistosomacide, niridazole, at 3 dose levels. Tumors were found in several organs, including stomach, lung, manary gland, ovary and bladder. Niridazole is, without doubt, carcinogenic to mice.
D000818:Animals; D002273:Carcinogens; D005260:Female; D008175:Lung Neoplasms / Q000139:chemically induced; D008297:Male; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced; D051379:Mice; D009374:Neoplasms, Experimental / Q000139:chemically induced*; D009560:Niridazole / Q000008:administration & dosage / Q000378:metabolism / Q000633:toxicity*; D010051:Ovarian Neoplasms / Q000139:chemically induced; D012737:Sex Factors; D013274:Stomach Neoplasms / Q000139:chemically induced; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced
D002273:Carcinogens; D009560:Niridazole