title: [Effect of choline chloride and calcium pantothenate on neuromuscular pathology caused by the administration of triamcinolone].
abstract: On isolated phrenico-diaphragmal preparations of 17-days old and adult rats it is shown that introduction of triamcinolon (for 3 days in amounts of 1.4 mg/kg) results in disruption of the neuro-muscular transmission, manifesting itself in a less intensive reaction to exogenous acetylcholine and alpha-tubocurarine. Administration of choline chloride and calcium pantothenate following that of triamcinolon does away with these effects of the glucocorticoid.
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology; D000367:Age Factors; D000818:Animals; D002794:Choline / Q000494:pharmacology*; D003964:Diaphragm / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D009132:Muscles / Q000187:drug effects; D009407:Nerve Block; D009468:Neuromuscular Diseases / Q000139:chemically induced*; D010205:Pantothenic Acid / Q000494:pharmacology*; D010791:Phrenic Nerve / Q000187:drug effects; D051381:Rats; D013997:Time Factors; D014221:Triamcinolone / Q000494:pharmacology*; D014403:Tubocurarine / Q000494:pharmacology
chemical_list: D010205:Pantothenic Acid; D014221:Triamcinolone; D002794:Choline; D000109:Acetylcholine; D014403:Tubocurarine
vernacular_title: Vliianie kholin-khlorida i pantotenata kal'tsiia na nervno-myshechnuiu patologiia, vyzvannuiu vvedeniem triamtsinolona