title: [MASCA-model of the biochemical-pharmacological drug research/ part 4: Structure-activity relationships and MANOVA (author's transl)].
abstract: The relation between the multivariate structure-activity analysis and the MANOVA is demonstrated on examples adapted from the combination analysis by Zipf, the dose-response and time-response analyses, the pharmacological screening and pharmacokinetics.
mesh_terms: D000704:Analysis of Variance; D001711:Biotransformation; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D007700:Kinetics; D008722:Methods; D008954:Models, Biological; D013223:Statistics as Topic; D013329:Structure-Activity Relationship; D013997:Time Factors
vernacular_title: MASCA-Modell der biochemisch-pharmakologischen Wirkstoff-Forschung 4. Mitteilung: Struktur-Wirkungs-Beziehungen und MANOVA