Groups of alpha-D- galactosyltransferase activity in sera of individuals with normal B phenotype. II. Relationship between transferase activity and red cell agglutinability.
In the Paris population of blood donors with normal B phenotype, two groups can be formed owing to their respective serum alpha-D-galactosyltransferase activity and red cell agglutinability with an anti-B antibody. Both parameters are closely correlated. The agglutinability groups partially overlap. In an African population from various ethnical origins, this correlation was observed only in some individuals. 11 among 20 subjects belonged to a third group defined by a high transferase activity. The third group with the strongest agglutinability previously described by GIBBS et al. [6] were not encountered. On the other hand, serum transferase activity varied inversely as agglutination scores with anti-H (Ulex). Both parameters are closely correlated but not in the same way in Caucasian as in African individuals. In the latter, this relation does not depend on the agglutinability group. The H antigen strength variability, according to ethnical origins, may explain these results.
D000017:ABO Blood-Group System; D044383:Black People; D001782:Blood Donors; D005260:Female; D005700:Galactosyltransferases / Q000097:blood*; D006384:Hemagglutination; D006801:Humans; D008297:Male; D010297:Paris; D010641:Phenotype; D044465:White People
D000017:ABO Blood-Group System; D005700:Galactosyltransferases