[Effect of protein-free diet on sulfobromophthalein hepatic transport (author's transl)].
Initial plasma disappearance rate and biliary excretion of intravenously injected sulfobromophthalein were studied in Wistar female rats fed a normal or a protein-free diet. Proteins and sulfobromophthalein distribution in the liver were studied by a gel filtration method. The results suggest that protein deficiency may produce an impaired sulfobromophthalein transference from plasma to liver cell due to a reduction of total hepatic proteins and of sulfobromophthalein-binding protein fraction responsible for liver uptake.
D000818:Animals; D001646:Bile / Q000032:analysis; D004044:Dietary Proteins / Q000008:administration & dosage; D005260:Female; D008099:Liver / Q000378:metabolism*; D008111:Liver Function Tests; D011485:Protein Binding; D011488:Protein Deficiency / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*; D051381:Rats; D013448:Sulfobromophthalein / Q000032:analysis
D004044:Dietary Proteins; D011506:Proteins; D013448:Sulfobromophthalein
Effecto de la dieta aproteica sobre el transporte hepatico de bromosulfaleina