General pharmacokinetic equations for linear mammillary models with drug absorption into peripheral compartments.
General equations are derived for the disposition functions of any compartment in a linear mammillary model, when the system input occurs into a peripheral compartment. Laplace transforms and matrix algebra are used to derive these equations. Equations describing the time-course of a drug in any compartment are readily obtainable using disposition and input functions.
D007408:Intestinal Absorption; D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000378:metabolism*
D004364:Pharmaceutical Preparations