Evoked potential changes during ethanol withdrawal in rats.
We have recently observed an increase in central nervous system excitability during intoxication and alcohol withdrawal in alcoholics. Our present results demonstrate a similar phenomenon in rats. The hyper-excitability caused by ethanol withdrawal is still present subsequent to the overt behavioral symptoms of withdrawal.
D000818:Animals; D004594:Electrophysiology; D000431:Ethanol / Q000494:pharmacology*; D005071:Evoked Potentials; D006801:Humans; D051381:Rats; D012154:Reticular Formation / Q000503:physiopathology*; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology*; D013997:Time Factors; D014793:Visual Cortex / Q000503:physiopathology*
D000431:Ethanol