title: [Success in a case of fulminant hepatitis treated with extracorporeal liver perfusion and exchange transfusion].
abstract: Extracorporeal perfusion of pig liver lasting 4 hr, followed by isovolaemic exchange (6 litres in 1 hr) were employed in the management of coma in a case of acute virus hepatitis. Liver perfusion led to temporary regression of coma, whereas transfusion was followed by gradual improvement in the clinical picture; this was apparently not a direct consequence of the procedure adopted. Assessment of the degree of purification obtained with these two methods offers an explanation for the difference in their clinical effectiveness.
mesh_terms: D000328:Adult; D000818:Animals; D005078:Exchange Transfusion, Whole Blood; D006501:Hepatic Encephalopathy / Q000209:etiology / Q000628:therapy*; D006506:Hepatitis A / Q000150:complications / Q000628:therapy*; D006801:Humans; D008099:Liver / Q000098:blood supply; D008297:Male; D010477:Perfusion; D013552:Swine
vernacular_title: Successo in un caso di epatite fulminante trattato con perfusione di fegato extracorporeo ed exsanguinotrasfusione