Androgenic function of a granulosa cell tumor.
Virilizing granulosa cell tumors are uncommon and have not been well studied hormonally. A hirsute woman with a cystic granulosa cell tumor of the ovary is presented. Plasma hormone levles obtained before and after surgery indicate testosterone production by the tumor with LH and FSH suppression. Plasma testosterone (T) and T-index returned to normal after tumor removal, and ovulation resumed.
D000328:Adult; D005260:Female; D006106:Granulosa Cell Tumor / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology / Q000503:physiopathology*; D013739:Testosterone / Q000096:biosynthesis
D013739:Testosterone