[Effects of L-dopa on FSH and LH secretion in men and women].
The behavior of plasma gonadotropins has been studied in amenorrhoic patients and in men suffering from disorders of spermatogenesis after L-DOPA administration. Neither clinical nor laboratory findings warrant hypotheses apt to interpret the different responses observed after the ingestion of the drug; nevertheless, keeping in mind the results reported in the literature, the relationship between L-DOPA and the hypothalamo-pituitary axis appears to deserve further study with the use of more accurate means of investigation and follow-up of the late effects observed in our research.
D000568:Amenorrhea / Q000188:drug therapy*; D002640:Chiari-Frommel Syndrome / Q000188:drug therapy*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D006065:Gonadotropins, Pituitary / Q000097:blood; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects; D007980:Levodopa / Q000494:pharmacology*; D007986:Luteinizing Hormone / Q000378:metabolism*; D008297:Male; D010902:Pituitary Gland / Q000187:drug effects*; D010903:Pituitary Gland, Anterior / Q000187:drug effects*; D011247:Pregnancy; D013091:Spermatogenesis / Q000187:drug effects*
D006065:Gonadotropins, Pituitary; D007980:Levodopa; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone