Sexual differences in the metabolism of salicylates.
During 6 h the plasma level of salicylates was followed after oral administration of aspirin. The plasma levels of salicylic acid were significantly lower in bull than in heifer calves during the whole observation period. The toxicity of the drug was higher in female animals.
D000818:Animals; D001241:Aspirin / Q000378:metabolism* / Q000633:toxicity; D002417:Cattle; D005260:Female; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D012459:Salicylates / Q000097:blood*; D012737:Sex Factors; D013997:Time Factors
D012459:Salicylates; D001241:Aspirin