[The unspecific reaction of inflammation in rickets due to lack of vitamin D (author's transl)].
10 children (3--18 months old) with Vit. D Deficiency Rickets were investigated by Rebuck skin windows for their ability to elicit unspecific inflammation before and after therapy. Differences to a control group (13 children) were statistically significant. In the acute phase of the disease beginning of inflammation is retarded, reduction of polymorphonuclear leucocytes in favour of mononuclear cells is less then in controls, the absolute quantity of exsudation is reduced too. After therapy inflammation is intensified and accelerated, but exsudation is still different from control children qualitatively and quantitatively. These findings add new facts to the data already known on impaired defence mechanisms in rickets.
D005260:Female; D006801:Humans; D007109:Immunity; D007223:Infant; D007239:Infections / Q000150:complications* / Q000473:pathology; D007962:Leukocytes; D008297:Male; D012279:Rickets / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D013997:Time Factors
Die unspezifische Entzündungsreaktion bei Vitamin-D-Mangel-Rachitis