Striato-nigral degeneration and Shy-Drager syndrome (idiopathic orthostatic hypotension).
The present paper reports on a case which evolved clinically with a Parkinson syndrome and attacks of orthostatic hypotension. Dystrophic lesions were found in the substrantia nigra, putamen and autonomic bulbo-medullary axis. This case demonstrates that striato-nigral degeneration of the Adams, van Bogaert and van der Eecken type and the Shy-Drager syndrome (orthostatic hypotension with neurologic syndrome) are part of the same pathiologic entity respesenting nervous multisystem degeneration developing in the presenium.
D000368:Aged; D001927:Brain Diseases / Q000150:complications*; D003342:Corpus Striatum; D006801:Humans; D007024:Hypotension, Orthostatic / Q000150:complications*; D008297:Male; D008526:Medulla Oblongata / Q000473:pathology; D010300:Parkinson Disease / Q000150:complications*; D011699:Putamen / Q000473:pathology; D013378:Substantia Nigra / Q000473:pathology; D013577:Syndrome