[A cytogenetic analysis of the antimutagenic action of alpha-tocopherol on spontaneous and radiation-induced chromosomal mutations].
The antimutagenic effect of alpha-tocopherol at concentrations of 1-10(-5)-1-10 mcC/ml was studied with respect to spontaneous and radiation-induced chromosome mutations in Allium fistulosum L. and Vicia faba L. It is established that at these concentrations alpha-tocopherol exhibits a significant antimutagenic activity, decreasing the frequency of chromosome mutations more than by 40-50%. No changes resulting from the antimutagenic effect of alpha-tocopherol were observed in the spectrum of structual mutations of chromosomes.
D002869:Chromosome Aberrations / Q000187:drug effects*; D003864:Depression, Chemical; D009154:Mutation / Q000187:drug effects*; D010944:Plants; D011831:Radiation Genetics; D014810:Vitamin E / Q000494:pharmacology*
D014810:Vitamin E
Tsitogeneticheskiĭ analiz antimutagennogo deĭstviia alfa-tokoferola na spontannye i indutsirovannye radiatsieĭ mutatsii khromosom