title: [Complications in chloroquin therapy].
abstract: Chloroquine and hydroxychloroquine are widely used in diseases  of connective tissue, especially in rheumatoid arthritis and systemic lupus erythematosus. However, various side effects are reported in many publications. In general these side effects are less important, e.g. those on the gastrointestinal tract and drug exanthema. Disorders of the haemopoetic system, the central nervous system, and peripheral neuromyopathy are rare. Only few reports exist about fetal damage. In contrary, severe problems result from eye complications such as reversible keratopathy and mostly irreversible retinopathy. If, however, chloroquine is administered, the necessity of exakt dosage and periodic ophthalmologic controls has to be stressed.
mesh_terms: D001168:Arthritis / Q000188:drug therapy; D002738:Chloroquine / Q000009:adverse effects*; D003095:Collagen Diseases / Q000188:drug therapy*; D005260:Female; D005315:Fetal Diseases / Q000139:chemically induced; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy; D009461:Neurologic Manifestations; D011247:Pregnancy; D012164:Retinal Diseases / Q000139:chemically induced; D012877:Skin Manifestations
chemical_list: D002738:Chloroquine
vernacular_title: Komplikationen unter Chloroquintherapie