Renal blood flow and function in vesico-ureteric reflux. An experimental study in the pig.
A unilateral, free, vesico-ureteric reflux was surgically created in six piglets. Three to four months later, glomerular and tubular function had decreased by about 50 per cent. The reflux also caused a reduction in the kidney's capacity to maintain a steady blood supply when the intravesical pressure was elevated.
D000818:Animals; D001794:Blood Pressure; D005919:Glomerular Filtration Rate; D007668:Kidney / Q000098:blood supply / Q000503:physiopathology*; D012039:Regional Blood Flow; D013552:Swine; D014655:Vascular Resistance; D014718:Vesico-Ureteral Reflux / Q000503:physiopathology*