Experimental uveitis induced by prostatic antigens.
Experimental uveitis was induced in male rats following their repeated systemic and intravitreous immunization with prostatic antigen and CFA. The ensuing uveitis was proved histologically. Heteroimmunized rabbits and female animals showed less response and the level of antibodies detected was lower. Anti-prostatic antibodies were determined by the TRC flocculation and PCA techniques. Ouchterlony's method gave positive results not only for prostatic but also for other ocular antigens when tested against the same test sera.
D000818:Animals; D000941:Antigens; D005260:Female; D005620:Freund's Adjuvant; D006168:Guinea Pigs; D008297:Male; D011467:Prostate / Q000276:immunology*; D011472:Prostatitis / Q000276:immunology; D051381:Rats; D014605:Uveitis / Q000276:immunology* / Q000473:pathology
D000941:Antigens; D005620:Freund's Adjuvant