[Weight reduction and glucose intolerance in obese subjects (author's transl)].
In a study extending over five years 35 of 70 excessively overweight patients with subclinical diabetes mellitus who had not significantly changed their weight, demonstrated a further deterioration in glucose tolerance, and manifest diabetes occurred in ten. In the remaining 35 patients who had achieved 20% weight reduction from the initial level glucose tolerance had become normal. The two groups were similar as to age, initial weight, and original degree of glucose intolerance. There was a significant correlation between loss of weight and increased glucose tolerance. No such correlation occurred with subgroups of patients whose initial overweight was more than +100 relative percentage and who had been over 50 years old at the start of the study.
D000328:Adult; D000375:Aging; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D048909:Diabetes Complications; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000378:metabolism*
D001786:Blood Glucose
Gewichtsreduktion und Glucose-Intoleranz bei Adipositas