title: [Metabolic activity of the N-acetylneuraminic acid of the principle gangliosides of the brain].
abstract: The turnover rate of N-acetylneuraminic acid of brain gangliosides (GT1, GD1b, GD1a, GM1) was studied following the injection of 2-14C-acetate. The specific activity of N-acetylneuraminic acid in GD1a and GM1 was found to be higher than in GD1b. The administration of aminasine reduced the specific activity of N-acetylneuraminic acid whereas chlorhydrate increased that of major brain ganglosides.
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D002697:Chloral Hydrate / Q000494:pharmacology; D002746:Chlorpromazine / Q000494:pharmacology; D005732:Gangliosides / Q000378:metabolism*; D051381:Rats; D012794:Sialic Acids / Q000378:metabolism*
chemical_list: D005732:Gangliosides; D012794:Sialic Acids; D002697:Chloral Hydrate; D002746:Chlorpromazine
vernacular_title: Metabolicheskaia aktivnost' N-atsetilneĭraminovoĭ kisloty osnovnykh gangliozidov mozga