[Influence of DOPA on the reactions of fetuses of adrenalectomized and ovariectomized rats to adrenaline stress].
It was shown that administration of noradrenaline precursor--L-DOPA (45 mg/kg) to pregnant adrenal- or ovariectomized rats restored the reaction of their fetuses to stress to the level characteristic of fetuses, whose mothers were falsely operated with their adrenal glands and ovaries remaining in situ. It is supposed that during the prenatal development in rats stress-reaction was realized with the participation of noradrenaline of the maternal CNS.
D000315:Adrenalectomy; D000818:Animals; D001921:Brain / Q000378:metabolism*; D002369:Castration; D004295:Dihydroxyphenylalanine / Q000378:metabolism / Q000494:pharmacology*; D004837:Epinephrine / Q000378:metabolism; D005260:Female; D005333:Fetus / Q000187:drug effects*; D008431:Maternal-Fetal Exchange; D009638:Norepinephrine / Q000378:metabolism*; D011247:Pregnancy; D051381:Rats; D013312:Stress, Physiological
D004295:Dihydroxyphenylalanine; D009638:Norepinephrine; D004837:Epinephrine
Vliianie DOFA na reaktsiiu plodov adrenaléktomirovannykh ili ovariéktomirovannykh krys na adrenalinovyĭ stress