[Changes in renal ultrastructure in acute poisoning with anticholinesterase substances (an experimental study)].
The authors present findings of their experimental study of effects produced by anticholinesterase substances of the type of pinochelin ether of methylfluoride-phosphoric acid (PEMA) on the ultrastructure of the kidney. The changes manifested themselves in vacuolization of podicytes and destruction of mitochondria of the tubules' epithelium, which was accompanied by an elevation in the activity of lysosomes.
D000208:Acute Disease; D000818:Animals; D007306:Insecticides / Q000506:poisoning*; D007678:Kidney Glomerulus / Q000648:ultrastructure; D007686:Kidney Tubules, Distal / Q000648:ultrastructure; D007687:Kidney Tubules, Proximal / Q000648:ultrastructure; D062025:Organophosphate Poisoning; D011817:Rabbits; D012999:Soman / Q000506:poisoning*
D007306:Insecticides; D012999:Soman
Izmeneniia ul'trastruktury pochek pri ostrom otravlenii antikholinésteraznaia veshchestvami (éksperimental'noe issledovanie)