Radiotherapy in malignant teratomas.
Twenty-seven patients with malignant teratoma, 19 of which received radiation, are presented and the radiation response analyzed. Radiotherapy seems most effective in the palliation of undifferentiated (embryonal) teratoma of the gonads and sacrococcygeal region in early childhood. It is less effective, yet useful, in undifferentiated gonadal and sacrococcygeal teratomas of older children and adults, but seems of little value in carcinomatous ovarian dermoids and in malignant mediastinal teratomas.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008479:Mediastinal Neoplasms / Q000532:radiotherapy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000532:radiotherapy*; D012186:Retroperitoneal Neoplasms / Q000532:radiotherapy; D012445:Sacrococcygeal Region; D013724:Teratoma / Q000532:radiotherapy*; D013736:Testicular Neoplasms / Q000532:radiotherapy