[Adequate dialysis (author's transl)].
The lack of peripheral neuropathy observed in peritoneal dialysis patients gave rise to the hypothesis that peritoneal membrane removes toxic solutes of larger dimensions than cuprophane membrane. Several "in vitro" and "in vivo" dialysis strategies have been selected. In the present paper the importance of residual renal function and the strategy of reduced dialysis schedule have been discussed. A trial with dialysis has been applied to 7 patients one of them treated for 20 months.


CONCLUSIONS
the well being of peritoneal dialysis and low flow dialysis patients, confirm that the accumulation of small molecules, within certain limits, is not dangerous. On the other hand the middle molecules hypothesis has never been confirmed by observing a real toxicity of that solutes in dialysis patients.
D005069:Evaluation Studies as Topic; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008567:Membranes, Artificial; D008970:Molecular Weight; D010530:Peritoneal Dialysis; D013997:Time Factors
D008567:Membranes, Artificial
Trattamento dialitico adeguato