Distributions, sex and age effects, and joint associations between phenotypes of 14 genetic systems in an Australian population sample.
The distribution of phenotypes of 14 polymorphic systems in a Melbourne sample have been determined. Some differences between males and females were found and the proportion of males of each PGM phenotype was shown to depend on the gene dosage in a linear manner. Among the more prominent effects of age noted, the median age of P1+ females was higher than for P1--females and this finding was associated with a positive linear regression of the proportion of P1+ women on age. No age effect was observed in males in this system. Some evidence for associations between phenotypes were found in 9 pairs of polymorphic systems.
D000135:Acid Phosphatase / Q000097:blood; D000243:Adenosine Deaminase / Q000097:blood; D000263:Adenylate Kinase / Q000097:blood; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001315:Australia; D001789:Blood Group Antigens; D003176:Complement C3; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D005828:Genetics, Population; D006242:Haptoglobins; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D010733:Phosphoglucomutase / Q000097:blood; D010734:Phosphogluconate Dehydrogenase / Q000097:blood; D011110:Polymorphism, Genetic; D012737:Sex Factors
D001789:Blood Group Antigens; D003176:Complement C3; D006242:Haptoglobins; D010734:Phosphogluconate Dehydrogenase; D000263:Adenylate Kinase; D000135:Acid Phosphatase; D000243:Adenosine Deaminase; D010733:Phosphoglucomutase