title: Inner ear pathologic features following mumps infection. Report of a case in an adult.
abstract: Temporal bone studies in an adult with a moderately severe, bilateral sensorineural hearing loss revealed bilateral cochlear changes 13 years after mumps infection. The organ of Corti was completely absent in the greater part of the superior horizontal basal limbs, with occasional hair cell loss throughout the rest of the cochlea. The outer sulcus cell area was degenerated. The stria vascularis was normal, as was the tectorial membrane, except for small hyaline droplets. The number of nerve fibers was extremely decreased in the spiral bony lamina of the basal turns. Basophilic material, possibily representing degeneration of otoliths, was present in the saccule and utricle, bilaterally, with small amounts in all of the ampullae. This was considered to be either a possible result of cytotoxic cancerocidal therapy, or an incidental nonspecific change.
mesh_terms: D000328:Adult; D002648:Child; D003051:Cochlea / Q000473:pathology; D007758:Ear, Inner / Q000473:pathology*; D005260:Female; D006311:Hearing Disorders / Q000209:etiology; D006801:Humans; D007759:Labyrinth Diseases / Q000209:etiology / Q000473:pathology*; D008875:Middle Aged; D009107:Mumps / Q000150:complications*