title: Impairment of active avoidance in rats with unilateral hypothalamic lesion.
abstract: Male albino rats with unilateral hypothalamic (ULH) lesion on either the right or left side were trained to acquire active shock avoidance in a two-way shuttle box. With 20 trials in a session per day, either group scored responses below 50% by the 8th day, while intact rats attained the criterion of 80% correct responses by the 5th day. It is concluded that intact lateral hypothalamic areas are essential for successful learning of active shock avoidance.
mesh_terms: D000368:Aged; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D004327:Drinking Behavior / Q000502:physiology; D005247:Feeding Behavior / Q000502:physiology; D007839:Functional Laterality; D006801:Humans; D007031:Hypothalamus / Q000502:physiology*; D008297:Male