title: [Enterobacter-osteomyelitis in two neonates (author's transl)].
abstract: Two boys aged up to 2 weeks suffered from enterobacter-sepsis. In both cases osteomyelitis developed in spite of treatment with Gentamycin or Gentamycin combined with Chepazolin. Both children were, taking accont of the risks, then treated with Chloramphenicol (100 mg/kg body weight/24 hours) and the first patient also, for a short time, with tetracyclin. In the second patient we saw a marrow depression dependent on Chloramphenicol and its dosage which disappeared rapidly, when the drug was withheld.
mesh_terms: D002701:Chloramphenicol / Q000009:adverse effects / Q000627:therapeutic use; D004756:Enterobacteriaceae Infections / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis* / Q000188:drug therapy; D018805:Sepsis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D013752:Tetracycline / Q000627:therapeutic use
chemical_list: D002701:Chloramphenicol; D013752:Tetracycline
vernacular_title: Enterobacter-Osteomyelitis bei zwei Säuglingen