title: [Antimicrobial action of potential isothiocyanate forming substances 7th communication (author's transl)].
abstract: A number of (N-aryl-dithiocarbamino)-alkanecarbonic acids bearing halogen substituents and related compounds are described which may be considered potential isothicyanate forming substances. The in vitro fungistatic activity of these compounds was investigated and the results obtained compared with those of captan and thiram. It was demonstrated that the halogen substituted (N-aryl)-dithiocarbamino)-alkanecarbonic acids exert an intensive fungistatic effect with a wide spectrum of activity and that the most active of them are equal to captan and thiram.
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002215:Captan / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical; D005658:Fungi / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D013329:Structure-Activity Relationship; D013859:Thiocarbamates / Q000378:metabolism / Q000494:pharmacology*; D013861:Thiocyanates / Q000096:biosynthesis*; D013893:Thiram / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D013859:Thiocarbamates; D013861:Thiocyanates; D013893:Thiram; D002215:Captan
vernacular_title: Die antimikrobielle Wirkung von potentiellen Isothiocyanat-Bildnern