title: [Clinical experiences with a new multi-effective penicillin "spectacillin", gained in the gynecological and obstetrical therapy (author's transl)].
abstract: With the new semi-synthetic ampicilline-derivate, we treated 28 female patients of gynecological, and 22 of obstetrical indications. Owing to bacterial infections by grampositive/gramnegative germs, in these cases an antibiotic therapy was indicated. The target therapy was based on clinical findings, the germ analysis and the antibiogram. Considering the degree of disease, the intravenous (3 x 2 grams per day) or the oral treatment (4 to 6 grams a day) has been effected during 6 days at least and 13 days as a maximum duration. The evaluation of the therapeutical results was made by means of the clinical cours as well as the germ findings. These two parameters showed the reliable effectiveness of "Spectacillin", whereas the low exanthemic rate must be emphasized.
mesh_terms: D000031:Abortion, Septic / Q000188:drug therapy; D000284:Administration, Oral; D000328:Adult; D000667:Ampicillin / Q000031:analogs & derivatives; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008875:Middle Aged; D010538:Peritonitis / Q000188:drug therapy; D011247:Pregnancy; D011645:Puerperal Infection / Q000188:drug therapy; D011704:Pyelonephritis / Q000188:drug therapy; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000667:Ampicillin
vernacular_title: Klinische Erfahrungen in der Gynäkologie und Geburtshilfe mit einem neuen Breitspektrumpenicillin