Oral contraceptives.
Variations in the side chains attached to the gonadal hormones can produce marked changes in the potency of these compounds and can even change their predominant actions. Modification of testosterone renders it less androgenic and greatly enhances its progestational effect. The antifertility action of oral contraceptives may be exerted through any of several mechanisms: supression of follicular development, suppression of ovum expulsion or changes in endometrium or cervical mucus.
D000740:Anemia / Q000517:prevention & control; D001943:Breast Neoplasms / Q000139:chemically induced; D056486:Chemical and Drug Induced Liver Injury; D003141:Communicable Diseases / Q000139:chemically induced; D003276:Contraceptives, Oral / Q000009:adverse effects*; D003279:Contraceptives, Oral, Sequential / Q000009:adverse effects* / Q000494:pharmacology; D003280:Contraceptives, Oral, Synthetic / Q000009:adverse effects* / Q000494:pharmacology; D004338:Drug Combinations; D045166:Estradiol Congeners / Q000494:pharmacology; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D005705:Gallbladder Diseases / Q000139:chemically induced; D005947:Glucose / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D002542:Intracranial Embolism and Thrombosis / Q000139:chemically induced; D007986:Luteinizing Hormone / Q000097:blood; D011247:Pregnancy; D045167:Progesterone Congeners / Q000494:pharmacology; D045165:Testosterone Congeners / Q000494:pharmacology; D013923:Thromboembolism / Q000139:chemically induced
D003276:Contraceptives, Oral; D003279:Contraceptives, Oral, Sequential; D003280:Contraceptives, Oral, Synthetic; D004338:Drug Combinations; D045166:Estradiol Congeners; D045167:Progesterone Congeners; D045165:Testosterone Congeners; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D005947:Glucose