Binding of thioridazine and some of its metabolites to human serum protein and human albumin.
The binding of thioridazine and some of its psychoactive metabolites to human serum and to human albumin was studied using equilibrium dialysis. A very important binding capacity was found for each of the products tested, but significant differences between binding to human serum and binding to human albumin were observed.
D000328:Adult; D000818:Animals; D001798:Blood Proteins / Q000378:metabolism*; D006801:Humans; D008297:Male; D008653:Mesoridazine / Q000097:blood; D011485:Protein Binding; D012709:Serum Albumin / Q000378:metabolism*; D013881:Thioridazine / Q000031:analogs & derivatives / Q000097:blood*
D001798:Blood Proteins; D012709:Serum Albumin; D008653:Mesoridazine; D013881:Thioridazine