Necropsy study on glomerulonephritis in the elderly.
The necropsy reports and clinical observations of 44 cases of glomerulonephritis occurring in patients over 55 years old were reviewed. Two-thirds of the patients died from a rapidly progressive renal disease with focal necrotizing and fibrosing glomerular lesions; half of these exhibited a granulomatous splenic trabeculitis; an associated vasculitis was found in only a minority of these cases. Another important group consisted of cases of acute diffuse glomerulonephritis which, as a rule, occurred in association with a major infection. There were only four cases of chronic sclerosing glomerulonephritis.
D000208:Acute Disease; D000367:Age Factors; D000368:Aged; D001344:Autopsy; D002908:Chronic Disease; D005260:Female; D005921:Glomerulonephritis / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009400:Nephrosclerosis / Q000473:pathology