The effect of isoprenaline and propranolol on rat myocardial ornithine decarboxylase.
The intraperitoneal injection of isoprenaline in rats caused an increase in myocardial ornithine decarboxylase activity which reached a maximum of about four times the control value one hour after the injection. The intraperitoneal injection of dl-propranolol had no effect on myocardial ornithine decarboxylase activity. The  injection of dl-propranolol 30 min before the injection of isoprenaline almost completely prevented the effect of isoprenaline.
D000818:Animals; D002262:Carboxy-Lyases / Q000378:metabolism*; D006321:Heart / Q000187:drug effects; D007545:Isoproterenol / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D008297:Male; D009206:Myocardium / Q000201:enzymology*; D009638:Norepinephrine / Q000378:metabolism; D009955:Ornithine Decarboxylase / Q000378:metabolism*; D005082:Physical Exertion; D011433:Propranolol / Q000494:pharmacology*; D051381:Rats; D013997:Time Factors
D011433:Propranolol; D002262:Carboxy-Lyases; D009955:Ornithine Decarboxylase; D007545:Isoproterenol; D009638:Norepinephrine