[Experimental studies of the effect of the restoration of a balanced diet on the endocrine glands injured by food deficits].
The problem of the extent to which changes in endocrine glands in case of protein or fatty deficiency are reversible has a great theoretical and practical bearing. Its elucidation appears to be particularly relevant in the management of the various forms of deficient feeding where restored whole-food diets exert a pronounced therapeutical effect. However, literature data on the issue are very scanty and rather dissenting. The structural changes in adenohypophysis, thyroidea, adrenals and sex glands were studied in 72 albino rats of the Wistar line which, following treatment with a diet poor in proteins and fats, were subjected to a recovery regimen by feeding them whole-food diets. For the purpose, histomorphological and histochemical tests were used. It was established that while in the animals deprived of fats, realimentation estrored the mophological profile of all the glands under study, among the rats fed protein poor diets, irreversible tissue changes were found in the adrenals and gonads. The results obtained are related to the direct action of the nutrient deficit, or to its deleterious effect on the tropic secretion of the hypophysis.
D000311:Adrenal Glands / Q000503:physiopathology; D000818:Animals; D003677:Deficiency Diseases / Q000503:physiopathology*; D004032:Diet; D004702:Endocrine Glands / Q000503:physiopathology*; D005260:Female; D008055:Lipids / Q000172:deficiency; D008297:Male; D009747:Nutritional Physiological Phenomena; D010053:Ovary / Q000503:physiopathology; D010902:Pituitary Gland / Q000503:physiopathology; D011488:Protein Deficiency / Q000503:physiopathology; D051381:Rats; D013737:Testis / Q000503:physiopathology; D013961:Thyroid Gland / Q000503:physiopathology; D013997:Time Factors
D008055:Lipids
Eksperimentalni prouchvaniia otnosno vliianieto na vuzstanovenoto pulnotsenno khranene vurkhu uvredeni ot khranitelni nedoimutsi zhlezi s vutreshna sekretsiia.