[Optimating the availability of homologous quaternary ammonium compounds/3rd communication: The influence of salts on in vitro distribution of benzilic acid esters of homologous dimethyl-(2-hydroxyethyl)-alkyl-ammoniumbromides (author's transl)].
The addition of NaBr, Na-butansulfonate or Na-trichloracetat increases the partition coefficients of homologous quaternary cholinesters of benzilic acid between n-octanol and water. In a three-phase model (water/n-octanol/water) thus the rates of equilibration increase considerably for hydrophilic compounds.
D001561:Benzilates; D001965:Bromides; D002073:Butanes; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004058:Diffusion; D007700:Kinetics; D000442:Octanols; D000644:Quaternary Ammonium Compounds; D012995:Solubility; D013329:Structure-Activity Relationship; D013451:Sulfonic Acids; D013499:Surface Properties; D013997:Time Factors; D014238:Trichloroacetic Acid
D001561:Benzilates; D001965:Bromides; D002073:Butanes; D000442:Octanols; D000644:Quaternary Ammonium Compounds; D013451:Sulfonic Acids; D014238:Trichloroacetic Acid
Zur Optimierung der Verfügbarkeit homologer quartärer Ammoniumverbindungen. 3. Mitteilung): Einfluss von Salzen auf die In-vitro-Verteilung von Benzilsäureestern homologer Dimethyl-(2-hydroxyäthyl)-alkyl-ammoniumbromide