title: Morphological and histochemical changes of ultimobranchial follicles of the rat thyroid in the course of postnatal life.
abstract: Morphological and histochemical changes of ultimobranchial follicles of thyroid have been investigated in rats from newborn to 18 months of age. The first well-delimited ultimobranchial follicles, though with no lumen, were detected in the thyroid gland of 10-day-old rats. At 30 days of age, follicles possessing regular lumina were present in the thyroid. With age, the follicles gradually increased in volume assuming extreme dimensions in adult age. The follicles displayed varying shapes from simple cysts to bizarre forms. From the age of 50 days the cells of the follicular wall are separated from the cell debris contained in the lumen. The latter gave a PAS positive reaction. The cells of the ultimobranchial follicles did not exhibit argyrophilia and metachromasia showing that they differ considerably from the C-cells likewise of ultimobranchial origin, which are known to give marked argyrophilic and metachromatic reactions.
mesh_terms: D000367:Age Factors; D000818:Animals; D005260:Female; D006651:Histocytochemistry; D008297:Male; D051381:Rats; D013961:Thyroid Gland / Q000166:cytology* / Q000378:metabolism; D014460:Ultimobranchial Body / Q000166:cytology* / Q000378:metabolism