title: Variations in Coxsackie virus pathogenicity in the course of routine isolations in suckling mice and cell cultures.
abstract: From 1961 to 1973 416 Coxsackie viruses were isolated, most of the isolations (303) being done in the last 5 years. Most of the isolates belong to a group A, with a predominance of types A6 and A8. Many variations were observed in strains belonging to the same type, as concerns their isolation in human embryo cell cultures and suckling mice; many Coxsackie A5, A6 and A8 strains showed a low pathogenicity for these animals.
mesh_terms: D000328:Adult; D000818:Animals; D002648:Child; D004622:Embryo, Mammalian; D004770:Enterovirus / Q000302:isolation & purification / Q000472:pathogenicity*; D006367:HeLa Cells; D006801:Humans; D051379:Mice; D014776:Virus Cultivation