title: X-linked nonspecific mental retardation. Report of a large kindred.
abstract: A seven-generation pedigree of apparent X-linked, nonspecific mental retardation is reported. There are 19 known affected males who appear to have received the gene through normal mothers. Retardation, lack of fine motor coordination, hyperactivity and a speech defect are the characteristics of affected individuals studied.
mesh_terms: D002648:Child; D003878:Dermatoglyphics; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D006948:Hyperkinesis; D008607:Intellectual Disability / Q000235:genetics*; D008297:Male; D010375:Pedigree; D012730:Sex Chromosomes; D012737:Sex Factors; D013064:Speech Disorders