Synthesis of tetrahydro-beta-carbolines from indoleamines via enzymatic formation of formaldehyde from 5-methyltetrahydrofolic acid.
D000818:Animals; D001921:Brain / Q000201:enzymology; D002243:Carbolines / Q000096:biosynthesis*; D002855:Chromatography, Thin Layer; D003545:Cysteine / Q000494:pharmacology; D005557:Formaldehyde / Q000378:metabolism*; D066298:In Vitro Techniques; D007211:Indoles / Q000096:biosynthesis*; D008168:Lung / Q000201:enzymology; D008745:Methylation; D011817:Rabbits; D051381:Rats; D012436:S-Adenosylmethionine / Q000378:metabolism; D012701:Serotonin / Q000031:analogs & derivatives / Q000378:metabolism; D013763:Tetrahydrofolates / Q000378:metabolism*; D014363:Tryptamines / Q000378:metabolism
D002243:Carbolines; D007211:Indoles; D013763:Tetrahydrofolates; D014363:Tryptamines; D005557:Formaldehyde; D012701:Serotonin; D012436:S-Adenosylmethionine; D003545:Cysteine