[Preliminary studies on anti-Brucella agglutinins and on immunoglobulins in subjects affected by cholera during the 1973 epidemic in the province of Bari].
The behaviour of brucella agglutinins in sera from 70 cholera patients has been investigated. Agglutinins for brucella, at titers of 1/40 or higher, occurred in 45 patients (64,2%); it has also been showed an antibody rise in 41 subjects with a peak titer during the second week, just like cholera agglutinins. This fact confirms the antigenic interrelationship between Vibrio cholerae and brucella group. The serum immunoglobulins, during the course of infection, have been determined. Mean levels of IgM were elevated during the second week of the disease, whereas the IgG increased during the third week, as occured in primary antibody responses. Levels of IgA in serum rose significantly during the first week of the cholera; the relations of serum IgA with S-IgA of intestinal mucosa might to explain the rapid increase of IgA in the serum.
D000373:Agglutinins / Q000302:isolation & purification*; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000917:Antibody Formation; D002002:Brucella / Q000276:immunology*; D002771:Cholera / Q000453:epidemiology / Q000276:immunology*; D004196:Disease Outbreaks / Q000453:epidemiology; D007136:Immunoglobulins / Q000302:isolation & purification; D007558:Italy
D000373:Agglutinins; D000907:Antibodies, Bacterial; D007136:Immunoglobulins
Ricerche preliminari sulle agglutinine anti-brucella e sulle immunoglobuline in soggetti affetti da colera durante l'epidemia del 1973 nella  provincia di Bari