[Comparative study of adenosine and inosine as corrigents of ACD (Acid Citrate Dextrose) solution in preservation of human blood].
The examination was made on the effects of adenosine and inosine on glycolysis in ACD stored human red cells. Total glycolytic capacity was checked by the incorporation of inorganic phosphate into the acid soluble nucleoside phosphates of erythrocytes. Adenosine and inosine increase the glycolysis in ACD stored human red cells. This stimulation depends on the nucleoside concentration used up to the saturation level (2.0 muM of adenosine or inosine/ml). By the saturation level it was demonstrated that adenosine gives 30%higher stimulation than inosine. It may be concluded that by the same conditions adenosine may serve as a better corrigens for ACD stored human blood.
D000241:Adenosine; D001793:Blood Preservation; D002951:Citrates; D005947:Glucose; D006019:Glycolysis; D006801:Humans; D007288:Inosine; D012996:Solutions
D002951:Citrates; D012996:Solutions; D007288:Inosine; D005947:Glucose; D000241:Adenosine
Uporedno ispitivanje adenozina i inozina kao korigensa ACD rastvora u konzervisanju ljudske krvi