[Effect of caffeine and phenamin on caudate inhibition of aggressive reactions in cats].
In chronic experiments conducted on cats it was shown that caffeine (10--30 mg/kg) failed to change agressive reactions developing in stimulation of the meso- or diencephalic structures. Phenamine (1--3 mg/kg) facilitated the appearance of emotional manifestations and lowered the threshold of the agressive response. Subliminal stimulation of the caudate nucleus in control experiments caused motor tranquilization and depressed the agressive behaviour to a lesser degree when practised against the background of the caffeine action. At the same time, phenamine abolished the influence not only of the threshold, but also of the subliminal stimulation of the caudate nucleus on the spontaneous motor activity and the rage behaviour.
D000374:Aggression / Q000187:drug effects*; D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D002110:Caffeine / Q000494:pharmacology*; D002415:Cats; D002421:Caudate Nucleus / Q000187:drug effects* / Q000502:physiology; D003864:Depression, Chemical; D004558:Electric Stimulation; D006801:Humans; D007031:Hypothalamus / Q000502:physiology; D009433:Neural Inhibition / Q000187:drug effects*; D011889:Rage / Q000187:drug effects; D013997:Time Factors
D002110:Caffeine; D000661:Amphetamine
Vliianie kofeine i fenamina na kaudatnoe tormozhenie agressivnykh reaktsiĭ koshek