title: Factor VIII and factor-VIII-related antigen in multiple myelomatosis and related conditions.
abstract: Factor VIII and factor-VIII-related antigen (FVIIIRA) were estimated in 19 patients with paraproteinaemia. The FVIIIRA levels were above the normal range in 12 cases with II of these showing an abnormal FVIII/FVIIIRA ratio. The patients could be subdivied into three groups according to their FVIIIRA levels: normal levels, levels greater than normal but less than 200%, greater than 200%. This subdivision correlated with the degree of bone involvement as assessed by radiological skeletal survey.
mesh_terms: D000328:Adult; D000941:Antigens / Q000032:analysis*; D005169:Factor VIII / Q000032:analysis* / Q000276:immunology; D006801:Humans; D007122:Immunoelectrophoresis; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D009101:Multiple Myeloma / Q000097:blood* / Q000276:immunology; D010265:Paraproteinemias / Q000097:blood* / Q000276:immunology
chemical_list: D000941:Antigens; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D005169:Factor VIII