[Age-related characteristics of the reaction of the myocardial adenyl system to pharmacological sympatholysis].
Rats aged 7, 30 days and 3-5 months were given intraperitoneally single doses (2.5 mg/kg) of reserpine. The content of the adenyl system compounds (ATP, ADP, AMP and inorganic phosphorus) was determined. It was shown that as regards the extent of ATP and ADP depression the 7-day old animals proved more sensitive to reserpine than were adult animals.
D000227:Adenine Nucleotides / Q000502:physiology*; D000244:Adenosine Diphosphate / Q000032:analysis; D000249:Adenosine Monophosphate / Q000032:analysis; D000255:Adenosine Triphosphate / Q000032:analysis; D000367:Age Factors; D000818:Animals; D006321:Heart / Q000187:drug effects*; D010758:Phosphorus / Q000032:analysis; D051381:Rats; D012110:Reserpine / Q000494:pharmacology; D013565:Sympatholytics / Q000494:pharmacology*; D013997:Time Factors
D000227:Adenine Nucleotides; D013565:Sympatholytics; D010758:Phosphorus; D000249:Adenosine Monophosphate; D000244:Adenosine Diphosphate; D012110:Reserpine; D000255:Adenosine Triphosphate
Vozrastnye osobennosti reaktsii adenilovoĭ sistemy miokarda na farmakologicheskuiu desimpatizatsiiu