Cell types originating from kidney explants of young and old mice.
Explants from young and old mouse kidneys give rise to two different cell types when placed in organ culture dishes. The two cell types differ in morphology and ability to grow in vitro. Explants from young mice give rise to one predominant cell type; those from old mice give rise to another. Our data supports the mosaic theory of aging.
D000375:Aging; D000818:Animals; D046508:Culture Techniques; D007668:Kidney / Q000166:cytology*; D008297:Male; D051379:Mice