[Comparative study of the changes in the EEG and cholinesterase activity in experimental Dipterex poisoning].
A systematic study is conducted on cats, poisoned with the organophosphorus insecticide Dipterex. The changes in spontaneous and induced cortical activity along with those in serum and erythrocyte cholinesterase after intraperitoneal and intramuscular injection of Dipterex are investigated. Against the background of lowered cholinesterase activity, recorded in all the experiments , the changes in EEG appear to be discrete and inconstant. Uron single treatment with Dipterex, desynchronization prevails in the spontaneous EEG, whereas in the responses induced by light stimulants an increase of delayed negative potentiale prevails. Upon repeated Dipterex introduction, theta-like waves appear, associated with activation of paroxysmal manifestations existing in advance. Finally, the correlation between changes in cholinesterase activity and EEG is discussed.
D000818:Animals; D002415:Cats; D002802:Cholinesterases / Q000097:blood*; D003344:Cortical Synchronization; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography; D004789:Enzyme Activation / Q000187:drug effects; D004912:Erythrocytes / Q000201:enzymology; D007273:Injections, Intramuscular; D007274:Injections, Intraperitoneal; D011041:Poisoning / Q000503:physiopathology; D014236:Trichlorfon / Q000506:poisoning*
D014236:Trichlorfon; D002802:Cholinesterases
Sravnitelno izsledvane na promenite v EEG i kholinesteraznata aktivnost pri eksperimentalna intoksikatsiia s diptereks.