title: [Disaccharidases of the small intestine mucosa in infants and children. "Normal values", log normal distribution and age dependence].
abstract: In 63 infants and children with a histological normal mucosa of the duodenum, without an isolated defect of enzyme and with a normal increase of xylose and glucose in serum after a combined xylose-lactose loading test the activities of disaccharidases were log normal distributed. The asymmetric distributions were transformed into symmetric ones and the geometric mean (x) as well as the range (+/- 2 s) of maltase, saccharase, isomaltase, lactase and trehalase were calculated. Only the activity of lactase shows a significant dependency on age. In the first year of age the lower limit (x -- 2 s) of this enzyme is much higher than later.
mesh_terms: D000367:Age Factors; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D004186:Disaccharidases / Q000378:metabolism*; D006651:Histocytochemistry; D006801:Humans; D007223:Infant; D007410:Intestinal Diseases / Q000201:enzymology / Q000473:pathology; D007413:Intestinal Mucosa / Q000201:enzymology* / Q000473:pathology; D007421:Intestine, Small / Q000201:enzymology* / Q000473:pathology
chemical_list: D004186:Disaccharidases
vernacular_title: Disaccharidasen der Dünndarmschleimhaut bei Säuglingen und Kindern -- "Normalwerte", Lognormalverteilung und Altersabhängigkeit--