The effect of magnesium sulfate on the absorption of acetylsalicylic acid and lithium carbonate from the human intestine.
Magnesium sulfate given orally in a hypertonic or isotonic solution did not alter the absorption of therapeutic doses of acetylsalicylic acid or lithium carbonate, despite a purgative effect in 10 volunteers. The concentration of magnesium in serum remained unchanged during the experiments.
D000328:Adult; D000368:Aged; D000931:Antidotes; D001241:Aspirin / Q000378:metabolism*; D005243:Feces; D006801:Humans; D006982:Hypertonic Solutions; D007408:Intestinal Absorption / Q000187:drug effects*; D007552:Isotonic Solutions; D008094:Lithium / Q000097:blood / Q000378:metabolism*; D008278:Magnesium Sulfate / Q000494:pharmacology*; D008875:Middle Aged; D012459:Salicylates / Q000097:blood
D000931:Antidotes; D006982:Hypertonic Solutions; D007552:Isotonic Solutions; D012459:Salicylates; D008278:Magnesium Sulfate; D008094:Lithium; D001241:Aspirin