title: Simulated flying performance after marihuana intoxication.
abstract: Ten pilots smoked, in counterbalanced order on a double blind basis, a social dose of marihuana (.09 mg/kg delta-9-tetrahydrocannabinol) and a matched placebo after being trained to fly a specific flight sequence on an ATC-510 flight simulator. In contrast to placebo, marihuana caused a gross decrement in flying performance, with increased prevalence of major errors, minor errors, altitude deviations, heading deviations, and radio navigation errors. These effects of active marihuana persisted for at least 2 hr and generally had disappeared by 4 to 6 hr after marihuana administration.
mesh_terms: D000337:Aerospace Medicine; D001359:Aviation; D002188:Cannabis / Q000633:toxicity*; D006801:Humans; D008297:Male; D009790:Occupations; D013647:Task Performance and Analysis