title: Plasma and erythrocyte concentrations of lithium.
abstract: The authors have studied the clinical response, EMG and EEG changes in 12 depressed patients after 28 days of lithium carbonate treatment of 1,200 mg daily. The findings confirm: (1) a high correlation between the degree of improvement and the RBC lithium: plasma lithium ratio on the 28th day; (2) a slight decrease in motor conduction velocity (m.c.v.) and increase of M-response duration during lithium treatment; (3) no correlation between EEG and lithium levels and percentage of improvement.
mesh_terms: D000328:Adult; D000368:Aged; D003863:Depression / Q000097:blood / Q000188:drug therapy*; D004569:Electroencephalography; D004576:Electromyography; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D008094:Lithium / Q000097:blood* / Q000627:therapeutic use; D008875:Middle Aged
chemical_list: D008094:Lithium