Direct cell mediated lympholysis in man. Cellular cytotoxic capacity of 100 normal, healthy blood donors.
The cellualr lymphocytotoxic capacity of 100 normal, healthy blood donors were investigated by the Direct Cell Mediated Lympholysis (DCML) test. The scorings were found to be distributed according to the normal, exhibiting a mean value of 0.1 Cr-51 release %, and an upper 1% significance level of 10.1 release 1%. It is concluded that lymphocytes from the peripheral blood of blood donors may well be used as negative biological controls in DCML testing of immunologically primed patients (e.g. after allotransplantation).
D001782:Blood Donors; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008214:Lymphocytes / Q000276:immunology*; D008297:Male