Lung scanning using microspheres labeled with radioactive isotopes in the diagnosis and evaluation of therapeutic results in pulmonary malignant neoplasms.
In 25 patients with malignant pulmonary neoplasms 38 scintiscanning investigations were carried out using the method of albumin microspheres labeled with 131I, technetium -99 m, or indium -113 m and macrocolloids of ferric hydroxide labeled with 113mIn. In 10 patients with infiltration of the main or lobar bronchi scintiscanning demonstrated in 9 cases complete absence of perfusion of one lung. In these cases routine radiological investigations demonstrated normal perfusion and aeration of lung parenchyma in the involved lung. Among 13 cases of carcinoma situated in segmental or subsegmental bronchi the areas with absent perfusion were in 7 cases larger than changes observed during radiological examination. Scintiscanning investigations were used also for evaluation of therapeutic results of synchronized chemotherapy in malignant neoplasms of this organ. Scintiscanning is a method well tolerated by the patients and it may be performed repeatedly in the same case for evaluation changes in perfusion disturbances caused by malignant lung neoplasms. It may be helpful in choice of a proper method of treatment.
D000368:Aged; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007553:Isotope Labeling; D008175:Lung Neoplasms / Q000175:diagnosis*; D008297:Male; D008863:Microspheres; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000175:diagnosis; D011877:Radionuclide Imaging / Q000379:methods*