[Increase in the number of antibody producing cells during combined cultivation of lymph node cells from immunized animals with intact bone marrow cells].
An increase in the amount of direct and indirect plaque-forming cells in mixed cultures of lymph node cells from mice primed and challenged with sheep red blood cells with syngenic and allogenic bone marrow cells from intact donors was observed. The amount of plaque-forming cells in mixed cultures reached the maximum level in 9--11 hours of cultivation and then fell to the initial level. The authors believe that in mixed cultures of lymph node cells from immune mice and bone marrow cells from intact donors there occurs an involvement into the antibody synthesis of new cells of one of the two cell populations cultured.
D000818:Animals; D000921:Antibody-Producing Cells; D001853:Bone Marrow; D001854:Bone Marrow Cells; D007109:Immunity; D008198:Lymph Nodes / Q000276:immunology*; D051379:Mice; D008805:Mice, Inbred A; D008808:Mice, Inbred CBA
Uvelichenie chisla antiteloprodutsentov pri sovmestnom kul'tivirovanii kletok limfaticheskikh uzlov immunizirovannykh zhivotnykh s kletkami intaktnogo kostnogo mozga