Spasmolytic effect of 4-valeryl 4-(3-chlorophenyl) 1-[3-(4-methylpiperazine)-propyl)-piperidine trihydrochloride.
The purpose of this work was to check the effect of 4-valeryl 4-(3--chlorophenyl) 1-[3-(4-methylpiperazine)-propyl]-piperidine, a new synthetic piperidine derivative, on the activity of smooth musculature of guinea pig isolated intestine. Direct and indirect myolytic action of this compound was found.
D000818:Animals; D006168:Guinea Pigs; D007422:Intestines / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010276:Parasympatholytics; D010879:Piperazines / Q000494:pharmacology*; D010880:Piperidines / Q000494:pharmacology*
D010276:Parasympatholytics; D010879:Piperazines; D010880:Piperidines