[Steroidogenic function of the intra-arterial trophoblast in the rat. Ultrastructural, histoenzymologic and biochemical data].
The ultrastructural study of the intra-arterial trophoblast has revealed in the pregnant Rat a steroidogenic activity which has been confirmed by histoenzymologic observations (presence of delta 5-3 beta-HSDH and 17 beta-HSDH). At the 15th day postcoitum an in vitro investigation upon the metabolism of steroid hormone precursors suggests that the steroids (oestrogens, progestogens and androgens) secreted by the intra-arterial trophoblast have a local action upon the wall of the uterine placental arteries and are actively concerned with an important part upon the utero-placental hemodynamic as a whole.
D000735:Androstenedione / Q000378:metabolism; D000738:Androsterone / Q000378:metabolism; D000818:Animals; D004967:Estrogens / Q000096:biosynthesis / Q000378:metabolism; D005260:Female; D006913:Hydroxysteroid Dehydrogenases / Q000378:metabolism; D066298:In Vitro Techniques; D010920:Placenta / Q000098:blood supply / Q000648:ultrastructure; D010926:Placental Hormones / Q000096:biosynthesis* / Q000378:metabolism; D011247:Pregnancy; D011284:Pregnenolone / Q000378:metabolism; D011374:Progesterone / Q000378:metabolism; D051381:Rats; D013739:Testosterone / Q000378:metabolism; D014327:Trophoblasts / Q000201:enzymology / Q000378:metabolism*; D014599:Uterus / Q000098:blood supply
D004967:Estrogens; D010926:Placental Hormones; D013739:Testosterone; D000735:Androstenedione; D011374:Progesterone; D011284:Pregnenolone; D000738:Androsterone; D006913:Hydroxysteroid Dehydrogenases
La fonction stéroïdogène du trophoblaste intra-artériel chez la ratte: données ultrastructurales, histoenzymologiques et biochimiques