title: Ataxia, depression, and dermatitis associated with the use of dichlorvos-impregnated collars in the laboratory cat.
abstract: Ataxia and depression developed in 21 of 50 (42%) laboratory cats wearing flea collars impregnated with 2,2-dichlorovinyl dimethyl phosphate (dichlorvos or DDVP) in a warm dry environment. Five (10%) of the cats died. Whole blood cholinesterase (ChE) activity was significantly (P smaller than 0.001) reduced in all cats and cervical dermatitis occurred in 37 (74%) of them.
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000505:Alopecia / Q000139:chemically induced; D000818:Animals; D001259:Ataxia / Q000139:chemically induced / Q000662:veterinary*; D002252:Carbon Tetrachloride Poisoning / Q000662:veterinary; D002371:Cat Diseases / Q000139:chemically induced*; D002415:Cats; D002802:Cholinesterases / Q000097:blood; D003863:Depression / Q000139:chemically induced; D003877:Dermatitis, Contact / Q000662:veterinary*; D004006:Dichlorvos / Q000633:toxicity*; D004890:Erythema / Q000139:chemically induced / Q000662:veterinary; D005260:Female; D006799:Housing, Animal; D006801:Humans; D006813:Humidity; D008297:Male; D005423:Siphonaptera; D013696:Temperature
chemical_list: D004006:Dichlorvos; D000410:Alanine Transaminase; D002802:Cholinesterases