title: [Zollinger-Ellison syndrome].
abstract: A survey of pathogenesis, pathobiochemistry, pathological anatomy, clinic, diagnostics and therapy of the Zollinger-Ellison-syndrome is given. The Zollinger-Ellison-syndrome is, it is true, relatively rare, but its limitation from the usual peptic ulcer has great practical consequences. The suspicion of a Zollinger-Ellison-syndrome is aroused by therapy-resistent ulcers, which in every third person are associated with a diarrhoea, by recidivations of ulcer after gastric operations and by a large basal secretion of acid. The decisive diagnostic means is the serum gastrin determination. The only promising therapy is, as a rule, the gastrectomy.
mesh_terms: D005753:Gastric Mucosa / Q000378:metabolism; D005755:Gastrins / Q000097:blood / Q000378:metabolism; D006801:Humans; D006961:Hyperparathyroidism / Q000209:etiology; D011183:Postoperative Complications / Q000401:mortality; D011379:Prognosis; D013270:Stomach / Q000503:physiopathology; D015043:Zollinger-Ellison Syndrome / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery
chemical_list: D005755:Gastrins
vernacular_title: Das Zollinger-Ellison-Syndrom