[Hyperplastic processes in cardiac muscle mitochondria exposed to toxic doses of adrenaline].
Experiments were conducted on albino rats; a study was made of hyperplastic processes in the mitochondria of the myocytes of the heart with the action of toxic adrenaline doses. A solution of adrenaline chloride was injested intramuscularly (3 mg/kg). Three types of mitochondria were revealed in electron microscopic study. Mitochondria of the first type were of the size and structure characteristic of the muscle cells of the myocardium. Mitochondria of the second type had a very dense, finegrained matrix and a great number of cristae per unit of the area. Mitochondria of the third type had two "sections" under the common external membrane, differing from one another by the matrix density, distribution and number of cristae. It is supposed that the ultrastructural peculiarities of each of the types reflected their functional condition.
D000818:Animals; D004837:Epinephrine / Q000506:poisoning*; D006321:Heart / Q000187:drug effects; D008931:Mitochondria, Muscle / Q000187:drug effects / Q000648:ultrastructure*; D009206:Myocardium / Q000473:pathology*; D051381:Rats
D004837:Epinephrine
Giperplasticheskie protsessy v mitokhondriiakh myshechnykh kletok serdtsa posle vozdeĭstviia toksicheskikh doz adrenalina