title: Guanidine inhibits tobacco mosaic virus RNA synthesis at two stages.
abstract: Guanidine (GD) inhibited tobacco mosaic virus (TMV) RNA synthesis at two different steps, depending on the concentration of GD used. The time-course of inhibition by 40 mM GD coincided with the time-course of RNA synthesis. However, 10 mM GD inhibited an earlier step that occurred prior to viral RNA synthesis.
mesh_terms: D003864:Depression, Chemical; D006146:Guanidines / Q000494:pharmacology*; D010947:Plants, Toxic; D012367:RNA, Viral / Q000096:biosynthesis*; D013997:Time Factors; D014026:Nicotiana / Q000382:microbiology; D014027:Tobacco Mosaic Virus / Q000254:growth & development / Q000378:metabolism*; D014779:Virus Replication / Q000187:drug effects
chemical_list: D006146:Guanidines; D012367:RNA, Viral