title: Murine and rat mammary tumors as models for the immunological study of human breast cancer.
abstract: The human breast cancer process and some aspects of experimental mammary cancer are compared in the light of Huxley's hypothesis that each neoplastic cell line may be viewed as a new obligate parasitic species derived from metazoan cells. Sufficient correlations are found to justify the hope that the viral-induced mouse mammary oncogenic process and the carcinogen-induced rat mammary system may serve as reasonable models of the human disease for immunological studies.
mesh_terms: D000367:Age Factors; D000818:Animals; D002471:Cell Transformation, Neoplastic; D004195:Disease Models, Animal; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced / Q000209:etiology / Q000276:immunology*; D051379:Mice; D008815:Mice, Inbred Strains; D011230:Precancerous Conditions / Q000473:pathology; D011374:Progesterone / Q000502:physiology; D011388:Prolactin / Q000502:physiology; D051381:Rats
chemical_list: D011374:Progesterone; D011388:Prolactin