Pancytopenia in an infant associated with sulfamethoxazole-trimethoprim therapy.
Pancytopenia in a seven-month-old baby is described and attributed to sulfamethoxazole-trimethoprim therapy. Plasma cells and histiocytes were prominent in the initial bone marrow examination and quite unlike the fatty hypocellular marrow usually seen in aplastic anemia.
D000741:Anemia, Aplastic / Q000139:chemically induced* / Q000473:pathology; D003371:Cough / Q000188:drug therapy; D004338:Drug Combinations; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D010950:Plasma Cells / Q000473:pathology; D013420:Sulfamethoxazole / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D014295:Trimethoprim / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use
D004338:Drug Combinations; D014295:Trimethoprim; D013420:Sulfamethoxazole