title: [The effect of adaptation to increased muscular activity on bodily sensitivity to insulin].
abstract: Systematic exercise increased the organism's sensitivity to the metabolic effect of insulin. When trained animals were subjected to low doses of insulin they showed a more significant decrease in the blood sugar and the free fatty acid contents as compared with the control (i.e. unadapted to systematic exercise) animals. No visible difference in glycogen contents was found due to the effect of hypoglycemic seizures which developed rather rapidly and were more obvious in trained animals. Administration of large doses of insulin did not cause any difference in the metabolic reactions of trained and untrained animals.
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006003:Glycogen / Q000378:metabolism; D007328:Insulin / Q000494:pharmacology*; D008112:Liver Glycogen / Q000378:metabolism; D009132:Muscles / Q000378:metabolism / Q000502:physiology*; D005082:Physical Exertion; D051381:Rats; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D008112:Liver Glycogen; D006003:Glycogen
vernacular_title: Vliianie adaptatsii k povyshennoĭ myshechnoĭ deiatel'nosti na chuvstvitel'nost' organizma k insulinu