title: Endotoxin leucoencephalopathy in the telencephalon of the newborn kitten.
abstract: Prolonged exposure of the neonatal kitten to a lipopolysaccharide results in a telencephalic leucoencephalopathy characterized by astrogliosis and necrosis. The visceral organs of neonatal kittens and the telencephalon of mature cats are relatively resistent to the adverse effects of this lipopolysaccharide.
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D002415:Cats; D003560:Cysts / Q000139:chemically induced; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004731:Endotoxins / Q000008:administration & dosage / Q000633:toxicity*; D005911:Gliosis / Q000139:chemically induced; D007968:Leukoencephalopathy, Progressive Multifocal / Q000139:chemically induced* / Q000473:pathology; D008070:Lipopolysaccharides / Q000633:toxicity; D009336:Necrosis / Q000139:chemically induced; D013687:Telencephalon
chemical_list: D004731:Endotoxins; D008070:Lipopolysaccharides