The oral antidiabetic agents.
Oral antidiabetic agents can be used to lower blood glucose levels in some adult-onset diabetics who do not have acute complications and in whom control of hyperglycemia by weight reduction alone or insulin treatment is not possible. Except for their investigational use, these agents have no place in the treatment of chemical or latent diabetes, or subclinical or suspected diabetes, and they are contraindicated in patients with diabetic ketoacidosis. Findings from the University Group Diabetes Progcted and judicious use of these drugs.
D000284:Administration, Oral; D000328:Adult; D001786:Blood Glucose; D001835:Body Weight; D002318:Cardiovascular Diseases / Q000139:chemically induced / Q000401:mortality; D003920:Diabetes Mellitus / Q000097:blood / Q000178:diet therapy / Q000188:drug therapy; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy; D003927:Diet, Diabetic; D004347:Drug Interactions; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced; D007004:Hypoglycemic Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D010629:Phenformin / Q000009:adverse effects; D014044:Tolbutamide / Q000009:adverse effects; D014280:Triglycerides / Q000097:blood
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D014280:Triglycerides; D014044:Tolbutamide; D010629:Phenformin