title: Synthesis and pharmacological properties of some 1-aryl-4(1H)-pyrido(2,3-d)pyrimidones.
abstract: Some 1-aryl-4(1H)-pyrido[2,3-d]pyrimidones were synthesized from the corresponding 2-anilinonicotinamides by cyclization with triethyl-orthoformate. This series of compounds is a new one with interesting antiinflammatory and hypno-sedative properties.
mesh_terms: D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis; D003500:Cyclization; D006993:Hypnotics and Sedatives / Q000138:chemical synthesis*; D008722:Methods; D011725:Pyridines / Q000138:chemical synthesis; D011744:Pyrimidinones / Q000138:chemical synthesis*
chemical_list: D000893:Anti-Inflammatory Agents; D006993:Hypnotics and Sedatives; D011725:Pyridines; D011744:Pyrimidinones