[Combined clofibrate-chlorpropamide therapy in diabetes insipidus complicated with diabetes mellitus].
The authors observed the incidence of diabetes mellitus and diabetes insipidus in three cases. The combined clofibrat-chlorpropamide treatment proved to be successful. They succeeded in ceasing the daily insuline by giving the two drugs together. The daily diuresis diminished considerably in all three patients. The authors advise the combined clofibrat-chlorpropamide treatment in the incidence of the two diseases. This is especially reasonable when there is a disturbance in the lipoid metabolism.
D002747:Chlorpropamide / Q000627:therapeutic use*; D002994:Clofibrate / Q000627:therapeutic use*; D048909:Diabetes Complications; D003919:Diabetes Insipidus / Q000150:complications / Q000188:drug therapy*; D004231:Diuresis / Q000187:drug effects; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007328:Insulin / Q000008:administration & dosage; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged
D007328:Insulin; D002994:Clofibrate; D002747:Chlorpropamide
Kombinierte Clofibrat-Chlorpropamid-Behandlung bei mit Diabetes mellitus kompliziertem Diabetes insipidus