[MASCA-model of the biochemical-pharmacological drug research. Part 3: Structure-activity relationships and KANORA (author's transl)].
The KANORA (multivariate regression and correlation analysis) leads to a combination with the multivariate structure-activity analysis which encloses the time-, dose-response and biological screening analysis. Drug-receptor interactions can be considered in connection with structure-action relationship. The importance of the analysis of "nonsense"-correlations (by using the partial correlation) and the model II of regression analysis is demonstrated.
D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D008954:Models, Biological; D011930:Reaction Time; D012044:Regression Analysis; D013223:Statistics as Topic; D013329:Structure-Activity Relationship
MASCA-Modell der biochemisch-pharmakologischen Wirkstoff-Forschung. 3. Mitteilung: Struktur-Wirkungs-Beziehungen und KANORA