N-(2-cyanethylene-)urea--an asparagine analogous cytostatic compound?
The carcinostatic effect of the hitherto unknown N-(2-cyanethylene) urea is descirbed. The possible mode of action as an asparagine antimetabolite is discussed.
D000818:Animals; D001215:Asparaginase / Q000627:therapeutic use; D002384:Catalysis; D005260:Female; D006868:Hydrolysis; D008297:Male; D009570:Nitriles / Q000627:therapeutic use; D051381:Rats; D012513:Sarcoma, Experimental / Q000188:drug therapy*; D014508:Urea / Q000031:analogs & derivatives* / Q000627:therapeutic use
D009570:Nitriles; D014508:Urea; D001215:Asparaginase