Limb malformations following maternal use of haloperidol.
A second case of severe limb malformations was observed following maternal use of haloperidol early in the first trimester of pregnancy. Haloperidol is teratogenic in mice, and may be teratogenic in humans.
D000014:Abnormalities, Drug-Induced; D000015:Abnormalities, Multiple / Q000139:chemically induced; D004359:Drug Therapy, Combination; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006220:Haloperidol / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D017880:Limb Deformities, Congenital; D008297:Male; D008431:Maternal-Fetal Exchange; D008774:Methylphenidate / Q000627:therapeutic use; D010672:Phenytoin / Q000627:therapeutic use; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011618:Psychotic Disorders / Q000188:drug therapy
D008774:Methylphenidate; D010672:Phenytoin; D006220:Haloperidol