Identification of HCV-associated antigen(s) in hepatocytes.
HCV-associated antigens (HCAg) were localized morphologically using immunofluorescence methods. Fluorescence was found in the cytoplasm of individual liver cells or in groups of cells. Nuclear fluorescence was not observed. Blocking and absorption studies suggest that HCAg is related to nucleocapsid or envelope proteins.
D000818:Animals; D000956:Antigens, Viral / Q000302:isolation & purification*; D002451:Cell Compartmentation; D002467:Cell Nucleus / Q000382:microbiology; D003593:Cytoplasm / Q000382:microbiology; D005453:Fluorescence; D016174:Hepacivirus / Q000302:isolation & purification*; D006526:Hepatitis C / Q000382:microbiology*; D018936:Hepatitis C Antigens; D006520:Hepatitis, Animal; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D008099:Liver / Q000382:microbiology*; D002679:Pan troglodytes
D000956:Antigens, Viral; D018936:Hepatitis C Antigens