Coumarins and the vitamin K-K epoxide cycle. Lack of resistance to coumatetralyl in warfarin-resistant rats.
D000818:Animals; D003374:Coumarins / Q000494:pharmacology*; D004351:Drug Resistance; D004852:Epoxy Compounds / Q000378:metabolism*; D004988:Ethers, Cyclic / Q000378:metabolism*; D005260:Female; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D011516:Prothrombin / Q000378:metabolism; D051381:Rats; D012737:Sex Factors; D014812:Vitamin K / Q000378:metabolism*; D014859:Warfarin / Q000494:pharmacology*
D003374:Coumarins; D004852:Epoxy Compounds; D004988:Ethers, Cyclic; D014812:Vitamin K; D014859:Warfarin; D011516:Prothrombin