Idiopathic non-syphilitic paroxysmal cold haemoglobinuria in children.
Three examples of non-syphilitic paroxysmal cold haemoglobinuria (PCH) in children are described which occurred, within a period of 16 days, in association with a febrile illness. No definite viral aetiology or obvious epidemiological association could be established. A Donath-Landsteiner antibody of anti-P specificity was demonstrated in all three patients. The serological aspects of PCH are critically discussed.
D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003080:Cold Temperature; D003298:Coombs Test; D005260:Female; D006457:Hemoglobinuria, Paroxysmal / Q000209:etiology; D006801:Humans; D008297:Male; D010127:P Blood-Group System
D000914:Antibodies, Viral; D010127:P Blood-Group System