[The role of subcortical structures in the formation of a chronic cortical epileptogenic focus].
The authors studied the significance in the "maturation" of the cortical chronic experimental epileptogenic focus. The studies were conducted in rabbits with the use of registration methods of a summarized bioelectric activity and activation of subcortical formation by electric current. It was established that the activation of inhibitory structures in the preconvulsive period facilitated the inhibition of "maturation" of the initial-cortical epileptogenic focus and an easier development of the convulsive attack in comparison with the control group (without stimulation of subcortical nuclei), while the activation of generalizing formations lead to more severe convulsive attacks.
D000818:Animals; D001931:Brain Mapping; D002421:Caudate Nucleus / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000503:physiopathology*; D004558:Electric Stimulation; D004594:Electrophysiology; D007031:Hypothalamus / Q000503:physiopathology*; D009434:Neural Pathways; D011817:Rabbits; D012640:Seizures / Q000503:physiopathology*
Rol' podkorkovykh obrazovaniĭ v formirovanii korkovogo khronischeskogo épileptogennogo ochaga