title: Marked enlargement of the left lobe of the liver causing a false-positive spleen image.
abstract: In 10 patients with a markedly enlarged left lobe of the liver, the posterior (prone) views (99mTc-sulfur colloid) revealed a false-positive splenic defect. In 1 case the defect was also apparent in the anterior view. In all but 1 case this pseudodefect was not present in the posterior image obtained standing up. Use of a spleen-specific or liver-specific radionuclide agent was necessary in that case. The authors caution against diagnosis from an apparently abnormal posterior image unless proved by other measures.
mesh_terms: D003937:Diagnosis, Differential; D006529:Hepatomegaly / Q000175:diagnosis*; D006801:Humans; D011187:Posture; D013159:Splenic Infarction / Q000175:diagnosis*; D013667:Technetium; D013679:Technology, Radiologic
chemical_list: D013667:Technetium