[The clinical significance of deficiency coagulopathy in relationship to consumption coagulopathy (authors' transl)].
A deficiency coagulopathy may lead to a coagulation defect in the presence of massive blood loss which is characterized by a dilution of the coagulation factors especially a dilution of the plasma fibrinogen and the platelets and a dilution of their function. Hemorrhages which are triggered by a coagulation defect (consumption coagulopathy) may be aggravated by the additional loss of coagulation factors. The combination of a coagulation coagulopathy with a deficiency coagulopathy results in a bad prognosis. A case of deficiency coagulopathy and a case of consumption coagulopathy with additional deficiency coagulopathy are reported, the clinical importance and the management of these conditions are discussed.
D000328:Adult; D001772:Blood Cell Count; D001778:Blood Coagulation Disorders / Q000150:complications / Q000175:diagnosis*; D001792:Blood Platelets; D003937:Diagnosis, Differential; D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006470:Hemorrhage / Q000150:complications*; D006801:Humans; D012771:Shock, Hemorrhagic / Q000150:complications
D005340:Fibrinogen
Die klinische Bedeutung der Verlustkoagulopathie in Abgrenzung zur Verbrauchskoagulopathie