title: Recurrent brain abscess associated with hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber disease)--case report.
abstract: A 53-year-old mentally handicapped female with hereditary hemorrhagic telangiectasia complicated by pulmonary arteriovenous fistula developed a recurrent brain abscess in the left frontal region. She responded well to surgical drainage and antibiotic therapy. Previously, she had two brain abscesses of the left parieto-occipital and right parietal regions removed on separate occasions at 38 and 40 years of age. Although pulmonary arteriovenous fistula was eventually confirmed by angiography at age 41 years, surgical removal of the pulmonary lesion was not indicated due to multiplicity and large vascular shunting. Early recognition of pulmonary arteriovenous fistula in patients with hereditary hemorrhagic telangiectasia is emphasized for diagnosis of brain abscess and prevention of recurrence.
mesh_terms: D001164:Arteriovenous Fistula / Q000150:complications; D001922:Brain Abscess / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010375:Pedigree; D011652:Pulmonary Circulation; D012008:Recurrence; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications* / Q000235:genetics