Time function of corticosteroid levels in the blood plasma of rats under the influence of 222Rn inhalation.
The time function of cortocosteroid level in plasma of rats under two different 222Rn concentrations was investigated. Both curves show a maximum after 8h. Whereas the higher activity of 222Rn produces a second maximum after 5 days, the lower activity reaches its second maximum not before 9 days. From both time functions, a two-step mechanism in the intracellular control can be concluded.
D000305:Adrenal Cortex Hormones / Q000097:blood*; D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D001853:Bone Marrow / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000378:metabolism; D009928:Organ Specificity; D011886:Radon / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D013997:Time Factors
D000305:Adrenal Cortex Hormones; D011886:Radon