[Preparation of some pyrido (2,3-e)-1,4-diazepines].
By treating pyrido (2,3-e)-1,4-diazepinones with alkyl halides, N4-alkylpyrido (2,3-e)-1,4-diazepines were obtained. In addition a number of N1-alkylpyrido (2,3-e)-1,4-diazepines were prepared from alkyltetrahydronaphthyridinones by the Schmidt reaction. Preliminary pharmacological screening of some of these compounds showed no appreciable activity.
D000818:Animals; D001381:Azepines / Q000138:chemical synthesis* / Q000494:pharmacology; D002319:Cardiovascular System / Q000187:drug effects; D002490:Central Nervous System / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D011725:Pyridines / Q000138:chemical synthesis* / Q000494:pharmacology; D013055:Spectrophotometry, Infrared
D001381:Azepines; D007202:Indicators and Reagents; D011725:Pyridines
Preparazione di alcune pirido (2,3-e)-1,4-diazepine