title: Malignant melanoma of the head and neck in children. Review of the literature and report of a case.
abstract: Perusal of the literature revealed that until 1970, 13 children with malignant melanoma of the head and neck had been reported. This group includes two cases of melanoma that developed in a giant cell nevus, as well as one case of congenital melanoma. The biologic features of prepubertal melanoma appear basically analogous to those of the adult variety. Malignant melanoma of the auricle is described in a 2 1/2-year-old child. Surgical therapy was given, and BCG vaccination was used as an adjuvant. The patient is alive and free of signs of the disease 2 1/2 years following the operation. This appears to be the third reported case of malignant melanoma of the external ear in a child.
mesh_terms: D002675:Child, Preschool; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007167:Immunotherapy; D008545:Melanoma / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D009362:Neoplasm Metastasis; D011379:Prognosis; D012867:Skin / Q000473:pathology