Comparison of intravenous oxytocin and prostaglandin E2 for accelerating labour.
In a prospective study of 52 consecutive women who required acceleration of labour intravenous prostaglandin E2 (PGE2) was used as the oxytocic agent. These mothers were matched for age, parity, height, gestational age, initial cervical dilatation, and station and position of the fetal head with 52 women whose labours were accelerated with oxytocin; both drugs were equally effective. Acceleration to delivery intervals, second-stage durations, the number of assisted deliveries, and Apgar scores were similar regardless of the oxytocic used. Although PGE2 compares well with oxytocin, it offers no further advantages and is more expensive and less well tried than oxytocin.
D000293:Adolescent; D000328:Adult; D001034:Apgar Score; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007748:Labor Stage, Second / Q000187:drug effects; D007751:Labor, Induced / Q000379:methods*; D007743:Labor, Obstetric / Q000187:drug effects; D010121:Oxytocin / Q000494:pharmacology / Q000627:therapeutic use*; D011247:Pregnancy; D011446:Prospective Studies; D011458:Prostaglandins E / Q000494:pharmacology / Q000627:therapeutic use*; D013997:Time Factors
D011458:Prostaglandins E; D010121:Oxytocin