[Structural and neurochemical characteristics of sex-dependent neurons of the brain transplanted to the anterior chamber of the eye].
Histological, electron microscopic and histoautoradiographic methods were used to study structural and neurochemical features of the development of neurons of the hypothalamic paraventricular nuclei (PVN) and the medullary nucleus of the solitary tract (NST), which had been grafted from 20-day-old rat fetuses into the anterior eye chamber of ovariectomized female rats not exposed (control group) and exposed (experimental group) to prolonged estrogen action (during 4 weeks). The exposure to estrogen stimulated the growth, cell differentiation, RNA transcription and synaptogenesis in the grafted PVN and NST neurons. The data obtained seem to provide additional evidence that PVN and NST neurons belong to sex-dependent brain neurons.
D000818:Animals; D016380:Brain Tissue Transplantation; D004958:Estradiol / Q000502:physiology; D005260:Female; D016332:Fetal Tissue Transplantation; D007498:Iris; D008297:Male; D008526:Medulla Oblongata / Q000166:cytology* / Q000196:embryology; D008854:Microscopy, Electron; D009474:Neurons / Q000166:cytology / Q000502:physiology / Q000637:transplantation* / Q000648:ultrastructure; D010286:Paraventricular Hypothalamic Nucleus / Q000166:cytology* / Q000196:embryology; D051381:Rats; D012733:Sex Differentiation / Q000502:physiology; D013739:Testosterone / Q000502:physiology; D016042:Transplantation, Heterotopic
D013739:Testosterone; D004958:Estradiol
Strukturnye i neĭrokhimicheskie osobennosti sekszavisimykh neĭronov mozga, transplantirovannykh v peredniuiu kameru glaza.