Intrauterine device increases the fibrinolytic activity of the rat endometrium at deciduation, a new aspect of its contraceptive effect.
The fibrinolytic activity of the endometrium of the two uterine horns in the rat was histochemically determined. One of the horns contained a plastic-IUD, the other served as control. The endometrium of the control horn was almost inactive in contrast with that of the IUD-horn in which fibrinolytic activity was apparent. The fibrinolytic activity induced by the IUD might be involved in the prevention of ova implantation.
D000818:Animals; D010064:Embryo Implantation; D004717:Endometrium / Q000502:physiology*; D005260:Female; D005342:Fibrinolysis; D006651:Histocytochemistry; D007434:Intrauterine Devices; D011247:Pregnancy; D051381:Rats