[Separation of pharmaceutical compounds using high-performance liquid chromatography. Influence of water II. (author's transl)].
The use of ternary solvent systems as mobile phases in combination with highly efficient chromatographic columns is of particular interest for the analysis of pharmaceutical and biological compounds. The solute-silanol group interactions decrease when the eluent is blended with water. Good selectivities are found with such systems.
D001463:Barbiturates / Q000032:analysis; D001569:Benzodiazepines / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D003984:Dibenzazepines / Q000032:analysis; D004364:Pharmaceutical Preparations / Q000032:analysis*; D010640:Phenothiazines / Q000032:analysis; D011743:Pyrimidines / Q000032:analysis; D014867:Water
D001463:Barbiturates; D003984:Dibenzazepines; D004364:Pharmaceutical Preparations; D010640:Phenothiazines; D011743:Pyrimidines; D014867:Water; D001569:Benzodiazepines
Séparation de produits pharmaceutiques par chromatographie en phase liquide à haute performance. Influence de l'eau. II