Arthritis of mice induced by Mycoplasma arthritidis. Humoral antibody and lymphocyte responses of CBA mice.
Peak arthritis occurred 7 days after intravenous injection of CBA mice with Mycoplasma arthritidis and persisted in some animals for 84 days. A marked leucocytosis was apparent for the first 21 days. Complement-fixing antibodies reached a peak 14 days after injection of the organisms and persisted at high levels for 84 days. Metabolic-inhibiting and mycoplasmacidal antibodies were present but at much lower titres.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000917:Antibody Formation; D001168:Arthritis / Q000209:etiology / Q000276:immunology* / Q000382:microbiology; D005260:Female; D007111:Immunity, Cellular; D037102:Lectins / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000494:pharmacology; D008213:Lymphocyte Activation; D051379:Mice; D008808:Mice, Inbred CBA; D009174:Mycoplasma / Q000302:isolation & purification; D009175:Mycoplasma Infections / Q000276:immunology*
D000907:Antibodies, Bacterial; D037102:Lectins; D008070:Lipopolysaccharides