title: 90 day dermal toxicity of DDVP in male rats.
abstract: Exposure of male rats to DDVP (21.4 mg/kg/day) through dermal painting for a period of 90 days did not produce any changes in skin or testis. None of the animals showed any clinical symptoms of DDVP poisoning or mortality during experimentation. Rapid degradation of DDVP and further its detoification in in liver of rats and other species of mammals seems to be the prime reason for the non-toxic effect of the insecticide.
mesh_terms: D000818:Animals; D004006:Dichlorvos / Q000633:toxicity*; D008297:Male; D051381:Rats; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology; D013737:Testis / Q000187:drug effects* / Q000473:pathology
chemical_list: D004006:Dichlorvos