A new method for increasing the chemotherapeutic drug concentration in the tumor tissue.
D000818:Animals; D001682:Biological Availability; D001702:Biopharmaceutics; D005354:Fibrosarcoma / Q000097:blood* / Q000188:drug therapy; D008297:Male; D008727:Methotrexate / Q000097:blood* / Q000627:therapeutic use; D009374:Neoplasms, Experimental / Q000097:blood / Q000188:drug therapy; D009638:Norepinephrine / Q000494:pharmacology*; D051381:Rats
D009638:Norepinephrine; D008727:Methotrexate