title: Occurrence of phosphenolpyruvate carboxylase in the extremely thermophilic bacterium Thermus aquaticus.
abstract: In the extreme thermophile Thermus aquaticus, phosphoenolpyruvate carboxylase catalyzes carbon dioxide fixation on the C3 metabolite phosphoenolpyruvate, producing oxaloacetate. In a moderately thermophilic Bacillus species this function is fulfilled by pyruvate carboyxlase. Like several of its mesophilic counterparts, the Thermus enzyme exhibits a requirement for acetyl coenzyme A.
mesh_terms: D000105:Acetyl Coenzyme A / Q000378:metabolism; D002245:Carbon Dioxide / Q000378:metabolism; D002474:Cell-Free System; D006088:Gram-Negative Aerobic Bacteria / Q000201:enzymology* / Q000254:growth & development / Q000378:metabolism; D008274:Magnesium / Q000378:metabolism; D010071:Oxaloacetates / Q000378:metabolism; D010728:Phosphoenolpyruvate / Q000378:metabolism; D010729:Phosphoenolpyruvate Carboxykinase (GTP) / Q000378:metabolism*; D011766:Pyruvate Carboxylase / Q000378:metabolism
chemical_list: D010071:Oxaloacetates; D002245:Carbon Dioxide; D000105:Acetyl Coenzyme A; D010728:Phosphoenolpyruvate; D010729:Phosphoenolpyruvate Carboxykinase (GTP); D011766:Pyruvate Carboxylase; D008274:Magnesium