Deciduoma formation in rats with cornified vagina.
In female rats given a single injection of 1.25 mg 5 alpha-dihydrotestosterone during neonatal life, reactivity of the vaginal mucosa to hormones was permanently altered, so that the rats, when adult, could show vaginal cornification under the hormonic conditions supportive of development of deciduomata in the uterus.
D000818:Animals; D000831:Animals, Newborn; D002369:Castration; D003656:Decidua; D013196:Dihydrotestosterone; D004717:Endometrium / Q000293:injuries; D004958:Estradiol; D005260:Female; D009092:Mucous Membrane / Q000473:pathology; D011247:Pregnancy; D011374:Progesterone; D051381:Rats; D014621:Vagina / Q000473:pathology; D014623:Vaginal Diseases / Q000139:chemically induced* / Q000150:complications / Q000473:pathology
D013196:Dihydrotestosterone; D011374:Progesterone; D004958:Estradiol