Effects of prior administration of Sn(II) complexes on in vivo distribution of 99mTc-pertechnetate.
This report evaluates the effect of prior administration of several clinically used Sn(II)-containing agents on in vivo distribution of 99mTc. Abnormal binding of 99mTc to red blood cells can occur after administration of pertechnetate to patients who have previously received tin-containing agents. Increased blood levels of tin from other causes may have similar effects.
D000818:Animals; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D009947:Organotin Compounds / Q000009:adverse effects*; D011877:Radionuclide Imaging; D051381:Rats; D013154:Spleen / Q000378:metabolism; D013667:Technetium / Q000097:blood / Q000378:metabolism
D009947:Organotin Compounds; D013667:Technetium