Acetylcholine induced alterations of 32Pi incorporation into phospholipids: lack of effects in human term placenta.
Fragments of noninnervated human placenta, a tissue rich in acetylcholine were incubated with 32Pi and drugs which modify cholinergic functions. The incorporation of 32Pi into placental polar phospholipids was measured in the presence or absence of 1X10(-4)M exogenous ACh. Particular attention was paid to phosphatidic acid, phosphatidyl inositol and phosphatidyl choline. There was no change in the intensity of labelling of any of the phospholipids due to the presence of ACh.
D000109:Acetylcholine / Q000494:pharmacology*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D010743:Phospholipids / Q000378:metabolism*; D010758:Phosphorus / Q000378:metabolism*; D010761:Phosphorus Radioisotopes; D010920:Placenta / Q000187:drug effects / Q000378:metabolism*; D011247:Pregnancy; D013997:Time Factors
D010743:Phospholipids; D010761:Phosphorus Radioisotopes; D010758:Phosphorus; D000109:Acetylcholine