[Longitudinal approaches to the problem of clinical heterogeneity of Alzheimer-type dementia].
A total of 160 patients with Alzheimer-type dementias (ATD), including 84 with Alzheimer's diseases (AD) and 76 with senile dementia (SD), were examined. The initial signs of the disease were analyzed by making a retrospective assessment of informative history data. The prospective follow-up involved clinical, neuropsychological and electrophysiological (EEC mapping, evoked potentials) studies by applying the standardized assessment of results. There was shown to be a set of clinical and paraclinical parameters for the status of ATD patients, indicating a distinct-quantitative and qualitative difference between patients with AD and those with SD and supporting the heterogeneity of ATD.
D000368:Aged; D000544:Alzheimer Disease / Q000145:classification / Q000175:diagnosis*; D001931:Brain Mapping; D003704:Dementia / Q000175:diagnosis; D003937:Diagnosis, Differential; D004569:Electroencephalography; D005071:Evoked Potentials; D005500:Follow-Up Studies; D006801:Humans; D012189:Retrospective Studies
Longitudinal'nye podkhody k probleme klinicheskoĭ geterogennosti dementsiĭ al'tsgeĭmerovskogo tipa.