[Fetal growth retardation: prevention. Review of the literature].
The principle underlying preventive treatment of fetal intrauterine growth retardation can only be considered after defining various groups that are at risk and early screening based on the obstetric history, biological tests, and recently using flow rates with Doppler techniques. The use of aspirin in preventive treatment of growth retardation originates in the pharmacological properties of its molecule which allow the re-establishment of a balance of the prostoglandins. Numerous authors have studied clinical effects, its harmlessness as well as the true indications for its use. As there have been no control studies the theoretical possibilities of using Beta-Mimetic drugs has not been tested. The use of ultrasound has made it possible to try to see whether there is an improvement in the fetal state of well-being when oxygen therapy is used by the mother as it is in certain extremes to see what effect it has on placental function. Its use as an effective prophylactic has not yet been demonstrated. Promising lines of research could be assessing the effects of immunological treatments that have already been suggested (especially gammaglobulin transfusions). They have been used prophylactically with success but the series are small for well defined immunological indications.
D000318:Adrenergic beta-Agonists / Q000494:pharmacology / Q000627:therapeutic use; D001241:Aspirin / Q000494:pharmacology / Q000627:therapeutic use; D005069:Evaluation Studies as Topic; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D006801:Humans; D008403:Mass Screening / Q000379:methods / Q000592:standards; D010102:Oxygen Inhalation Therapy / Q000592:standards; D011247:Pregnancy; D012307:Risk Factors; D016216:Ultrasonography, Prenatal; D005719:gamma-Globulins / Q000494:pharmacology / Q000627:therapeutic use
D000318:Adrenergic beta-Agonists; D005719:gamma-Globulins; D001241:Aspirin
Hypotrophie foetale: prévention. Revue de la littérature.