The role of imipramine hydrochloride on plasma transaminase and glucose level on rats under altitude stress.
The effect of exposure of albino rats to simulated high altitude stress of 5000 metres for 3 and 6 hrs on plasma transaminases, non-protein nitrogen (NPN), total protein percentages and blood sugar levels have been studied both with and without the administration of an anti-stress drug Imipramine HCl at 2.0 mg/kg body weight. The drug appears to have a slight hepatotoxic effect.
D000410:Alanine Transaminase / Q000097:blood; D000531:Altitude; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001786:Blood Glucose / Q000032:analysis*; D007099:Imipramine / Q000494:pharmacology*; D008297:Male; D051381:Rats; D013268:Stimulation, Chemical; D013312:Stress, Physiological / Q000097:blood* / Q000201:enzymology; D000637:Transaminases / Q000097:blood*
D001786:Blood Glucose; D000637:Transaminases; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D007099:Imipramine