[Therapy of ulcus ventriculi with Caved-S. Use of the gastrocamera for diagnosis and control of therapy].
36 patients with a ventricular ulcer demonstrated by endoscopy and secured by histology, were given 2 tablets Caved-S 4 times a day for 4 weeks. Clinical parameters were subjective complaints, such as pain and heartburn, which after a relatively short time, many patients declared to have diminished or ceased completely. Objective parameters were endoscopic explorations before beginning of the treatment, i.e. gastroscopy and biopsy, examinations by gastro-camera and in some cases chromography to exclude a possible malignancy. The control examinations were performed almost exclusively by gastro-camera, and that after 2 and 4 weeks. The ulcer healing stage could be clearly defined after Ohmori and Miwa (1971), its localisation and size were also recorded. Altogether it can be said, that the preparation Caved-S, by a working-principle not as yet exactly defined in all details, effects rapid healing endoscopically provable, but that ulcers with a special localisation, e.g. in the angulus-area of the posterior wall, require a longer healing time according to expectation. Clinically relevant side effects were not observed. Thus it can be concluded that Caved-S is very suitable for the treatment of ventricular ulcers. The preparation has a spasmolytical component leading quickly to freedom from pain, and a protective component effecting a healing tendency which can be demonstrated by endoscopic methods. It must be said, however, that this protective healing-promoter factor has not yet been defined pharmacologically.
D000536:Aluminum Hydroxide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001729:Bismuth / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002254:Carbonates / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D004334:Drug Administration Schedule; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D005773:Gastroscopy; D006035:Glycyrrhiza; D006801:Humans; D008276:Magnesium Hydroxide; D008297:Male; D010781:Photography; D010936:Plant Extracts; D010946:Plants, Medicinal; D017693:Sodium Bicarbonate; D013276:Stomach Ulcer / Q000175:diagnosis / Q000188:drug therapy*
D002254:Carbonates; D004338:Drug Combinations; D010936:Plant Extracts; C002792:aluminum hydroxide, bismuth subnitrate, deglycyrrhizinised liquorice, magnesium carbonate, sodium bicarbonate drug combination; D000536:Aluminum Hydroxide; D017693:Sodium Bicarbonate; D008276:Magnesium Hydroxide; D001729:Bismuth
Zur Therapie des Ulcus ventriculi mit Caved-Si. Einsatz der Gastrokamera zur Diagnostik und Therapiekontrolle