Ultrastructure of blood platelets in cattle with East Coast fever.
The sequence of ultrastructural changes of bovine platelets during the fatal course of East Coast fever was swelling; formation of vacuoles,  pseudopodia, and indentations; then thrombocytorrhexis and degranulation; and finally, thrombocytolysis. These changes led to thrombocytopenia and release of serotonin, resulting in petechiations and pulmonary edema.
D000818:Animals; D001792:Blood Platelets / Q000648:ultrastructure*; D002417:Cattle; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D008297:Male; D013801:Theileriasis / Q000097:blood*; D014617:Vacuoles / Q000648:ultrastructure