Uptake and metabolism of beta-alanine and L-carnosine by rat tissues in vitro: role in nutrition.
Uptake and metabolism of the dipeptide L-carnosine (beta-alanyl-L-histidine) and of the free amino acid beta-alanine were studied in scraped mucosal epithelium of jejunum, kidney cortex slices, and intact hemidiaphragm muscle of the rat. These preparations expose plasma membranes with various orientations to amino nitrogen nutrition.
D000409:Alanine / Q000378:metabolism*; D000596:Amino Acids / Q000494:pharmacology; D000625:Aminooxyacetic Acid / Q000494:pharmacology; D000818:Animals; D001692:Biological Transport; D002336:Carnosine / Q000378:metabolism*; D003964:Diaphragm / Q000378:metabolism*; D004151:Dipeptides / Q000378:metabolism*; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000378:metabolism; D007583:Jejunum / Q000378:metabolism*; D007672:Kidney Cortex / Q000378:metabolism*; D007700:Kinetics; D009842:Oligopeptides / Q000494:pharmacology; D051381:Rats; D012964:Sodium / Q000378:metabolism; D013997:Time Factors
D000596:Amino Acids; D004151:Dipeptides; D009842:Oligopeptides; D000625:Aminooxyacetic Acid; D002336:Carnosine; D012964:Sodium; D000409:Alanine