title: [Concentration course of Na-Penicillin G in wound secretions following vascular surgery].
abstract: After infusion of 10 and 20 M.I.U. of Na-penicilline G, the concentrations in serum, wound exudation, and urine were analysed, at equal points of time, following vascular reconstruction; pharmacokinetic data were calculated as well. The importance of local concentration of antibiotics for therapy and prevention of infections is emphasized - according to pharmacokinetics - in relation to the blood level. Simultaneously, the influence of pathological changes is discussed and represented by a brief case follow-up.
mesh_terms: D000368:Aged; D005122:Exudates and Transudates / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D008875:Middle Aged; D010400:Penicillin G / Q000008:administration & dosage / Q000378:metabolism*; D013530:Surgical Wound Infection / Q000517:prevention & control; D014656:Vascular Surgical Procedures
chemical_list: D010400:Penicillin G
vernacular_title: Konzentrationsverlauf von Na-Penicillin G im Wundsekret Gefässoperierter