title: Blighted ovum: ultrasonic, histopathologic and hormonal considerations.
abstract: Thirty women experiencing early pregnancy failure (blighted ovum) were studied at frequent intervals with serial measurements of serum human chorionic gonadotropin (beta-hCG), progesterone (P4) and estradiol (E2). The diagnosis of blighted ovum had previously been made by careful ultrasonic examination (s). Histopathologic findings in the placenta were studied in all cases. Hormonal levels were variable and in most of the cases indistinguishable from normal pregnancies. In only 50% of the cases the histopathologic examination revealed findings compatible for the blighted ovum criteria.
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood*; D018997:Chorionic Gonadotropin, beta Subunit, Human; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D010063:Ovum / Q000000981:diagnostic imaging / Q000473:pathology*; D010446:Peptide Fragments / Q000097:blood*; D010920:Placenta / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology*; D011374:Progesterone / Q000097:blood*; D014463:Ultrasonography
chemical_list: D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments; D011374:Progesterone; D004958:Estradiol