title: The effect of methoxyflurane on pulmonary vascular resistance and hypoxic pulmonary vasoconstriction in the isolated perfused cat lung.
abstract: The effects of methoxyflurane on pulmonary vascular resistance and the pulmonary vasoconstrictor response to alveolar hypoxia were studied in isolated cat lungs perfused at a constant flow. Methoxyflurane decreased pulmonary vascular resistance and depressed the pulmonary vasoconstrictor response to hypoxia.
mesh_terms: D000818:Animals; D002415:Cats; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D000860:Hypoxia / Q000503:physiopathology*; D066298:In Vitro Techniques; D008733:Methoxyflurane / Q000494:pharmacology*; D010477:Perfusion; D011651:Pulmonary Artery / Q000187:drug effects; D011652:Pulmonary Circulation / Q000187:drug effects*; D014655:Vascular Resistance / Q000187:drug effects*; D014666:Vasomotor System / Q000187:drug effects*
chemical_list: D008733:Methoxyflurane