Neuronal substrate of classical conditioning in the hippocampus.
Neuronal activity in dorsal hippocampus was recorded in rabbits-during classical conditioning of nictitating membrane response, with tone as conditioned stimulus and corneal air puff as unconditioned stimulus. Unit activity in hippocampus rapidly forms a temporal neuronal "model" of the behavioral response early in training. This hippocampal response does not develop in control animals given unpaired stimuli.
D000200:Action Potentials; D000818:Animals; D003214:Conditioning, Classical / Q000502:physiology*; D003215:Conditioning, Eyelid / Q000502:physiology; D008568:Memory / Q000502:physiology; D011817:Rabbits