Gentic control of the immune response to the Ea-2 alloantigen system of the mouse. I. The humoral antibody response.
The immunization of selected congenic strains and hybrids against the Ea-2.1 cellular alloantigen of the mouse demonstrated that the hammagglutinating antibody response to Ea-2.1 is regulated by a gene or genes associated with the H-2 gene complex. H-2r and H-2b are, respectively, responder and non-responder haplotypes.
D000818:Animals; D000917:Antibody Formation; D005796:Genes; D006649:Histocompatibility Antigens; D007109:Immunity; D007519:Isoantigens; D051379:Mice; D008815:Mice, Inbred Strains
D006649:Histocompatibility Antigens; D007519:Isoantigens