title: Microtubule fascicles in the stem processes of cultured sensory ganglion cells.
abstract: Microtubule fascicles, resembling those characterizing the initial segment of multipolar neurons, have been observed by electron microscopy within and close to the origin of the stem process of some unipolar ganglion cells in explant cultures of embryonic chick dorsal root ganglia. Each fascile comprised 2-6 closely spaced parallel microtubules linked by electron dense cross-bridges. Since similar observations have been made on stem processes in vivo, the possibility that linked microtubules occur commonly in this site is considered. The observations are discussed in relation to a possible correlation between the presence of microtubule fascicles and the initiation of action potentials.
mesh_terms: D000200:Action Potentials; D000818:Animals; D001369:Axons / Q000648:ultrastructure*; D002642:Chick Embryo; D046508:Culture Techniques; D005727:Ganglia, Spinal / Q000502:physiology / Q000648:ultrastructure*; D008870:Microtubules / Q000502:physiology / Q000648:ultrastructure*