Consanguinity and familial mental retardation.
Studies made in a group of patients with mental retardation showed that there was a high degree of parental consanguinity of the order of 30.3%. Index cases with parental consanguinity showed a relatively higher prevalence where more than one sib was affected. Cases with metabolic defects were also more common among cases with parental consanguinity. There is a need for studies in the general population in order to understand the biological significance of consanguinity.
D003241:Consanguinity; D005260:Female; D006801:Humans; D007194:India; D008607:Intellectual Disability / Q000235:genetics*; D008297:Male; D012559:Schizophrenia / Q000235:genetics