Analysis of intercellular distributions of chromatid aberrations.
59 intercellular distributions of chemically induced and spontaneous chromatid aberrations were analyzed for goodness of fit in respect of the Poisson (PD), the geometrical (GD), and the negative binomial distributions (NBD). The data are excellently described by the NBD. This distribution can be deduced from a model out of the queueing theory and is based on the hypothesis of restitution. Estimators are obtained for the ratio of restitution and induction processes involved in the origin of chromosomal aberrations.
D000477:Alkylating Agents; D002842:Chromatids; D002869:Chromosome Aberrations; D004392:Dwarfism / Q000235:genetics; D005199:Fanconi Anemia / Q000235:genetics; D006801:Humans; D007962:Leukocytes; D008954:Models, Biological; D011336:Probability; D013269:Stochastic Processes; D013577:Syndrome
D000477:Alkylating Agents