[The biopolymer metabolism of the connective tissue in the aorta under intraventricular injections of neuropeptides].
The metabolism of connective tissue biopolymers in the blood serum and in the aorta under repeated intraventricular injections of P-substance, L-enkephalin and B-endorphine was studied in chronic experiments on rabbits. The alternations of the central neurochemical processes, caused by prolonged intraventricular injections of neuropeptides were proved to lead to intensification of metabolic processes in the connective tissue characterized by the accumulation of its biopolymers in the aorta wall. The injection of P-substance, in contrast to opioid peptides, is accompanied by more marked alternations.
D000818:Animals; D001011:Aorta / Q000187:drug effects* / Q000378:metabolism; D001704:Biopolymers; D003238:Connective Tissue / Q000187:drug effects* / Q000378:metabolism; D004743:Enkephalin, Leucine / Q000008:administration & dosage; D007276:Injections, Intraventricular; D009479:Neuropeptides / Q000008:administration & dosage*; D011817:Rabbits; D013373:Substance P / Q000008:administration & dosage; D013997:Time Factors; D001615:beta-Endorphin / Q000008:administration & dosage
D001704:Biopolymers; D009479:Neuropeptides; D013373:Substance P; D004743:Enkephalin, Leucine; D001615:beta-Endorphin
Obmen biopolimerov soedinitel'noĭ tkani v aorte pri intraventrikuliarnykh vvedeniiakh neĭropeptidov.