[Lactic acidosis induced by excessive ingestion of metformin].
The authors report on a case of lethal lactate acidosis during acute metformine and barbiturate poisoning. The study of energetic substrates and glucoregulation hormones demonstrated a blockade of hepatic gluconeogenesis.
D000138:Acidosis / Q000139:chemically induced*; D000328:Adult; D001645:Biguanides / Q000506:poisoning; D006728:Hormones / Q000378:metabolism; D006801:Humans; D007773:Lactates; D008297:Male; D008687:Metformin / Q000097:blood / Q000506:poisoning*; D009888:Opipramol / Q000506:poisoning; D010530:Peritoneal Dialysis; D010634:Phenobarbital / Q000506:poisoning; D011041:Poisoning / Q000628:therapy; D013997:Time Factors
D001645:Biguanides; D006728:Hormones; D007773:Lactates; D008687:Metformin; D009888:Opipramol; D010634:Phenobarbital
Acidose lactique induite par l'ingestion excessive de metformine