Electroencephalographic changes following intraamniotic prostaglandin F2 alpha administration for therapeutic abortion.
Electroencephalograms were obtained on 43 patients undergoing therapeutic second trimester abortion using intraamniotic prostaglandin F2alpha. Recordings were made before and 4 hours after prostaglandin administration, as well as 4 hours after the abortion. At 4 hours after prostaglandin administration, 30% of the women had abnormal tracings, while 50% of the women had abnormal recordings 4 hours postabortion. Although the changes consisted primarily of mild generalized or lateralized slowing, 4 patients developed paroxysmal activity not initially present. This finding would seem to suggest a potential relationship between PGF2alpha administration and clinical seizures.
D000032:Abortion, Therapeutic; D000650:Amnion; D004569:Electroencephalography; D004827:Epilepsy / Q000139:chemically induced; D005260:Female; D006801:Humans; D007267:Injections; D011247:Pregnancy; D011446:Prospective Studies; D011460:Prostaglandins F / Q000009:adverse effects* / Q000627:therapeutic use; D012640:Seizures / Q000139:chemically induced
D011460:Prostaglandins F