title: The effect of a copper IUD and various "inert" Iuds on the histological picture of the rabbit endometrium during early pseudopregnancy and pregnancy.
abstract: The influence of a copper IUD and two "inert" IUDs on the histological picture of the rabbit endometrium during early pseudopregnancy and early pregnancy was studied. The copper IUD markedly inhibited the endometrial maturation during the first five days of both pseudopregnancy and pregnancy. The "inert" IUDs had no such effect. The copper IUD prevented the normal response of the rabbit uterus to 17-beta-estradiol in castrated animals. The observed effects of the copper IUD might seriously interfere with the normal process of implantation.
mesh_terms: D000818:Animals; D002369:Castration; D003300:Copper; D004717:Endometrium / Q000033:anatomy & histology* / Q000187:drug effects; D005260:Female; D007434:Intrauterine Devices; D008938:Mitosis / Q000187:drug effects; D011247:Pregnancy; D011270:Pregnancy, Animal; D011555:Pseudopregnancy; D011817:Rabbits; D013997:Time Factors
chemical_list: D003300:Copper