The microvasculature of the spleen.
A method for examining the microvasculature of the dog spleen by angiography is described and the findings are related to morphological studies. The marginal sinus of the lymphoid follicle has been shown to be an important part of the vascular pathway in the spleen. It allows intimate mixing of blood elements and spleen cells and it is suggested that this plays an important immunological role. The control of blood flow to the lymphoid follicle is discussed but requires further elucidation.
D000792:Angiography / Q000379:methods; D000818:Animals; D001466:Barium Sulfate; D002244:Carbon; D002404:Catheterization; D003287:Contrast Media; D004285:Dogs; D008833:Microcirculation / Q000000981:diagnostic imaging*; D012039:Regional Blood Flow; D013154:Spleen / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000187:drug effects; D014662:Vasoconstrictor Agents / Q000494:pharmacology
D003287:Contrast Media; D014662:Vasoconstrictor Agents; D001466:Barium Sulfate; D002244:Carbon