The use of intramuscular propantheline in the short bowel syndrome.
A patient is presented with the short bowel syndrome who because of massive diarrhea was unable to maintain fluid and electrolyte balance with the aid of the usual antidiarrhea drugs. Her bowel remnant consisted of approximately 155 cm of proximal jejunum. Intramuscular propantheline has allowed this patient to function normally for the past 36 months. Balance studies are presented to document the benefit of this drug. Propantheline's effectiveness is probably secondary to its marked slowing of intestinal motility.
D000328:Adult; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000188:drug therapy*; D007422:Intestines / Q000601:surgery*; D011183:Postoperative Complications / Q000188:drug therapy*; D011413:Propantheline / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D013577:Syndrome
D011413:Propantheline