Effect of ethyl acetate on the transport of sodium and glucose in the hamster small intestine in vitro.
The effect of ethyl acetate on Na+, water and glucose transport, as well as on glucose and electrolyte intracellular concentrations in everted and cannulated sacs of hamster jejunum, have been studied. Ethyl acetate, a substance that easily penetrates and delivers energy to the cell, strongly stimulates net glucose and Na+ transport. The explanation of the experimental results takes into account the possibility of the existence of an active extrusion of glucose at the level of the basolateral membrane of the enterocyte.
D000085:Acetates / Q000494:pharmacology*; D000818:Animals; D001692:Biological Transport; D001693:Biological Transport, Active; D001834:Body Water / Q000378:metabolism; D006224:Cricetinae; D005947:Glucose / Q000378:metabolism*; D066298:In Vitro Techniques; D007408:Intestinal Absorption / Q000187:drug effects*; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism*; D007583:Jejunum / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism*
D000085:Acetates; D012964:Sodium; D005947:Glucose; D011188:Potassium