title: [Which uric acid value is in need of treatment?].
abstract: Asymptomatic hyperuricemia should be treated only if the plasma uric acid levels are around 10 mg/100 ml or more on several determinations. In addition, patients on a purine-free diet who excrete more than 600 mg uric acid per 24 h should be treated. In both cases, treatment is intended to be prophylactic against gouty nephropathy. At present there is no evidence that primary hyperuricemia alone is a risk factor for early atherosclerosis and especially coronary artery disease. However, more attention should be paid to the accompanying risk factors such as obesity, hyperlipoproteinemia, diabetes mellitus and hypertension.
mesh_terms: D000493:Allopurinol / Q000627:therapeutic use; D001553:Benzbromarone / Q000627:therapeutic use; D002951:Citrates / Q000627:therapeutic use; D003327:Coronary Disease / Q000517:prevention & control; D006073:Gout / Q000188:drug therapy / Q000517:prevention & control; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D006973:Hypertension / Q000150:complications; D007041:Hypoxanthine Phosphoribosyltransferase / Q000172:deficiency; D007674:Kidney Diseases / Q000517:prevention & control; D007926:Lesch-Nyhan Syndrome / Q000150:complications; D009765:Obesity / Q000517:prevention & control; D014527:Uric Acid / Q000097:blood*
chemical_list: D002951:Citrates; D014527:Uric Acid; D001553:Benzbromarone; D000493:Allopurinol; D007041:Hypoxanthine Phosphoribosyltransferase
vernacular_title: Welcher Harnsäurewert bedarf der Behandlung