Effect of malnutrition on susceptibility of mice to Trypanosoma musculi: vitamin A-deficiency.
Vitamin A-deficiency was studied in mice infected with Trypanosoma musculi. Irrespective of diet, trypomastigotes (trypanosomes) appeared in peripheral tail blood of all inoculated mice after 6-day incubation periods. On the average, vitamin A-deficient mice had parasitemias about 10 times greater than animals fed a complete diet and 8 times pair-fed controls. Parasitemias lasted longer in vitamin-deficient hosts, and reached a maximum five days later than those from control hosts.
D000818:Animals; D000917:Antibody Formation; D001835:Body Weight; D005260:Female; D051379:Mice; D014352:Trypanosomiasis / Q000209:etiology* / Q000276:immunology; D014801:Vitamin A / Q000276:immunology; D014802:Vitamin A Deficiency / Q000150:complications*
D014801:Vitamin A