title: Treatment of connective tissue sarcomas by local excision followed by radioactive implant.
abstract: Thirty-two cases of connective tissue sarcoma were treated by local excision immediately followed by a radioactive implant, sometimes supplemented by external radiation. The method is effective in preventing local recurrence, and is particularly valuable for patients in whom persistent local recurrences following simple excision have occurred. The patient experiences little extra discomfort, and complications are unusual; hazard to staff is low. Long-term survival appears to be just as good in our series as in others in which radical surgery was used, the radical surgery has the disadvantages of greater operative morbidity and mortality, causes greater disfiguration, and may in any case be impossible for tumours in certain anatomical sites.
mesh_terms: D003238:Connective Tissue; D006801:Humans; D009364:Neoplasm Recurrence, Local; D011879:Radiotherapy Dosage; D011883:Radium / Q000627:therapeutic use; D012509:Sarcoma / Q000532:radiotherapy* / Q000601:surgery
chemical_list: D011883:Radium