Decreased incidence of renal cell carcinoma in rats with one kidney ingesting N-4-(4'-fluorobiphenyl)acetamide.
Buffalo strain male rats, 12 weeks of age, ingesting 0.04% N-4-(4'-fluorobiphenyl)acetamide in a semisynthetic diet with both kidneys intact were more susceptible to the development of hyperplasia and carcinomas of the kidney than were rats with a uninephrectomy.
D015073:2-Acetylaminofluorene / Q000031:analogs & derivatives; D000818:Animals; D002273:Carcinogens; D002277:Carcinoma / Q000139:chemically induced*; D007680:Kidney Neoplasms / Q000139:chemically induced*; D008113:Liver Neoplasms / Q000139:chemically induced; D008297:Male; D009392:Nephrectomy; D051381:Rats; D011915:Rats, Inbred BUF
D002273:Carcinogens; D015073:2-Acetylaminofluorene