The suppression of mouse spontaneous locomotor activity by the ingestion of deuterium oxide.
The spontaneous locomotor activity of the laboratory mouse is significantly depressed by the ingestion of deuterium oxide. The response, which is reversible, is a retilinear one with up to 70% reduction in activity with the administration of 25% heavy water.
D000818:Animals; D003903:Deuterium / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D051379:Mice; D009043:Motor Activity / Q000187:drug effects*; D013997:Time Factors
D003903:Deuterium