Childhood Kaposi's sarcoma: clinical features and therapy.
Twelve cases of childhood Kaposi's sarcoma seen at the Uganda Cancer Institute over the last 7 years are reported. The disease presents mainly as generalized lymphadenopathy, with sparsely and anomalously distributed cutaneous nodules, and has a higher proportion of females with the disease than in the adult form. The histology is usually of mixed cell type. If not treated, childhood Kaposi's sarcoma runs a fulminating course, but disease control with chemotherapy is associated with prolonged survival.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003606:Dacarbazine / Q000627:therapeutic use; D003609:Dactinomycin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D008199:Lymphadenitis / Q000209:etiology; D008297:Male; D012075:Remission, Spontaneous; D012514:Sarcoma, Kaposi / Q000175:diagnosis* / Q000188:drug therapy; D012737:Sex Factors; D014750:Vincristine / Q000627:therapeutic use
D003609:Dactinomycin; D014750:Vincristine; D003606:Dacarbazine