Nonenzymic joining of oligoadenylates on a polyuridylic acid template.
3',5'-Linked hexa-adenylic acid with a 2',3'-cyclic phosphate terminus [(A5A less than p] couples on a polyuridylic acid template in the presence of ethylenediamine to form the dodecamer (24 percent) and octadecamer (5 percent). The bond produced is largely that of the 2',5' isomer.
D000249:Adenosine Monophosphate; D055598:Chemical Phenomena; D002621:Chemistry; D005029:Ethylenediamines; D009843:Oligoribonucleotides; D011072:Poly U
D005029:Ethylenediamines; D009843:Oligoribonucleotides; D011072:Poly U; D000249:Adenosine Monophosphate