Abnormal serum lactate dehydrogenase isoenzyme in a case of laryngeal carcinoma and thyrotoxicosis.
An abnormal lactate dehydrogenase (LDH) isoenzyme was found in the serum of a patient with laryngeal carcinoma and hyperthyroidism. On electrophoresis it migrated as an additional band between LDH-1 and LDH-2. Follow-up studies suggested that this higher molecular weight, rather thermostable LDH isoenzyme, might have originated from the cancer tissue, though a possible relationship with the thyrotoxic state cannot be excluded.
D004355:Drug Stability; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications / Q000201:enzymology*; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D007822:Laryngeal Neoplasms / Q000150:complications / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D008970:Molecular Weight
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase