Blood bank reagents: some problems related to preservatives and dyes.
Occasionally the additives used for the storage, preservation, and coloring of blood bank reagents are a source of anomalous a-glutination reactions. Discrepancies in ABO cell and serum grouping or agglutination of cells used for both antibody detection and identification may be related to the presence of these materials in blood bank reagents. These substances include acriflavin and other dyes; antibiotics, such as penicillin and neomycin; EDTA; caprylate; and occasionally saline. The literature is reviewed regarding this problem.
D000017:ABO Blood-Group System; D000371:Agglutination; D001771:Blood Banks; D001793:Blood Preservation; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D007106:Immune Sera; D007202:Indicators and Reagents; D012709:Serum Albumin
D000017:ABO Blood-Group System; D007106:Immune Sera; D007202:Indicators and Reagents; D012709:Serum Albumin