title: The suppression of mouse spontaneous locomotor activity by the ingestion of deuterium oxide.
abstract: The spontaneous locomotor activity of the laboratory mouse is significantly depressed by the ingestion of deuterium oxide. The response, which is reversible, is a retilinear one with up to 70% reduction in activity with the administration of 25% heavy water.
mesh_terms: D000818:Animals; D003903:Deuterium / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D051379:Mice; D009043:Motor Activity / Q000187:drug effects*; D013997:Time Factors
chemical_list: D003903:Deuterium