title: A rheumatoid-like arthritis in calves.
abstract: Arthritis characterized by lameness. Joint swelling and purulent synovial fluid was seen in a group of dairy replacement heifers. Mycoplasma was cultured from one joint aspirate, but all bacterial cultures were negative. Antiglobulins were demonstrated by double diffusion precipitin tests in the serum and synovial fluid. Due to the clinical and clinical pathological similarities to rheumatoid arthritis in man, the disease was called rheumatoid-like arthritis. The presence of antiglobulin may indicate antibody in the synovial fluid explaining the difficulty in culturing a causative agent.
mesh_terms: D000818:Animals; D001172:Arthritis, Rheumatoid / Q000276:immunology / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology; D009174:Mycoplasma / Q000302:isolation & purification; D012217:Rheumatoid Factor / Q000032:analysis; D013582:Synovial Fluid / Q000166:cytology / Q000382:microbiology
chemical_list: D012217:Rheumatoid Factor