Occurrence of phosphenolpyruvate carboxylase in the extremely thermophilic bacterium Thermus aquaticus.
In the extreme thermophile Thermus aquaticus, phosphoenolpyruvate carboxylase catalyzes carbon dioxide fixation on the C3 metabolite phosphoenolpyruvate, producing oxaloacetate. In a moderately thermophilic Bacillus species this function is fulfilled by pyruvate carboyxlase. Like several of its mesophilic counterparts, the Thermus enzyme exhibits a requirement for acetyl coenzyme A.
D000105:Acetyl Coenzyme A / Q000378:metabolism; D002245:Carbon Dioxide / Q000378:metabolism; D002474:Cell-Free System; D006088:Gram-Negative Aerobic Bacteria / Q000201:enzymology* / Q000254:growth & development / Q000378:metabolism; D008274:Magnesium / Q000378:metabolism; D010071:Oxaloacetates / Q000378:metabolism; D010728:Phosphoenolpyruvate / Q000378:metabolism; D010729:Phosphoenolpyruvate Carboxykinase (GTP) / Q000378:metabolism*; D011766:Pyruvate Carboxylase / Q000378:metabolism
D010071:Oxaloacetates; D002245:Carbon Dioxide; D000105:Acetyl Coenzyme A; D010728:Phosphoenolpyruvate; D010729:Phosphoenolpyruvate Carboxykinase (GTP); D011766:Pyruvate Carboxylase; D008274:Magnesium