Criteria for diagnosis of temporary gluten intolerance.
Strict criteria for the diagnosis of temporary gluten intolerance are formulated in the light of the case of an 8-week-old infant with severe diarrhoea and failure to thrive, who recovered on an elimination diet that was gluten-free. 8 weeks later an oral challenge with 2.5 g twice daily of powdered gluten for one day produced diarrhoea, weight loss, and impaired xylose absorption. Gluten was successfully reintroduced into the diet 9 months later without incident. Jejunal histology remains normal after 26 months of a daily diet that contains 5 to 10 g gluten.
D005983:Glutens / Q000009:adverse effects*; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism; D007223:Infant; D007231:Infant, Newborn; D007583:Jejunum / Q000473:pathology; D008286:Malabsorption Syndromes / Q000175:diagnosis* / Q000178:diet therapy; D008297:Male; D013997:Time Factors; D014994:Xylose / Q000378:metabolism
D007070:Immunoglobulin A; D005983:Glutens; D014994:Xylose