Nafcillin treatment of Staphylococcus aureus meningitis.
Serial serum and cerebrospinal fluid nafcillin concentrations were determined in a patient successfully treated with nafcillin (200 mg/kg per day) for Staphylococcus aureus bacteremia and meningitis. Nafcillin and methicillin cerebrospinal fluid concentrations were compared.
D000368:Aged; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000188:drug therapy*; D008712:Methicillin / Q000134:cerebrospinal fluid / Q000627:therapeutic use; D009254:Nafcillin / Q000134:cerebrospinal fluid / Q000627:therapeutic use*; D010403:Penicillin Resistance; D018805:Sepsis / Q000188:drug therapy; D013203:Staphylococcal Infections / Q000134:cerebrospinal fluid / Q000188:drug therapy*; D013211:Staphylococcus aureus / Q000187:drug effects*
D009254:Nafcillin; D008712:Methicillin