title: [Somatostatin -- a review (author's transl)].
abstract: Somatostatin, a peptide isolated from ovine hypothalami, prevents growth hormone secretion in vivo and in vitro. Moreover, somatostatin interferes with the secretion of various other hormones: TSH insulin, glucagon, gastrin, VIP and GIP. Under certain conditions a blunting effect on the secretion of prolactin and ACTH can be demonstrated.
mesh_terms: D000172:Acromegaly / Q000188:drug therapy; D000818:Animals; D004064:Digestive System / Q000032:analysis; D005088:Exocrine Glands / Q000378:metabolism; D005755:Gastrins / Q000378:metabolism; D005934:Glucagon / Q000378:metabolism; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000032:analysis; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D010908:Pituitary Hormones, Anterior / Q000378:metabolism; D010973:Platelet Adhesiveness / Q000187:drug effects; D013004:Somatostatin / Q000032:analysis / Q000494:pharmacology / Q000502:physiology*; D013972:Thyrotropin / Q000378:metabolism
chemical_list: D005755:Gastrins; D007328:Insulin; D010908:Pituitary Hormones, Anterior; D013004:Somatostatin; D013972:Thyrotropin; D013006:Growth Hormone; D005934:Glucagon
vernacular_title: Somatostatin