[Pharmacological reactivity in cricetus aureus uterus (author's transl)].
The motility of the isolated Cricetus auratus uterus was studied and compared to that of other species. Oxitocyn, epinephrine, norepinephrine, histamine, 5-hydroxy-tryptamine and acetylcholine were used as spasmogen agents. There was not contractil response with epinephrine or nor-epinephrine. Histamine reduced basal tonus. There was contraction with acetylcholine, oxytocin and 5-hydroxy-tryptamine. Cricetus auratus uterus appeared more sensitive when the contraction was registered by the isometric method. No taquifilaxy was produced by 5-hydroxy-tryptamine, as opposed to such effect in rat uterus. The Cricetus auratus uterus has, therefore, shown similar reactivity to that of rat, but different from rabbit and guinea-pig.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001337:Autonomic Agents / Q000494:pharmacology*; D006224:Cricetinae; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology; D009119:Muscle Contraction / Q000187:drug effects*; D009638:Norepinephrine / Q000494:pharmacology; D010121:Oxytocin / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D012701:Serotonin / Q000494:pharmacology; D013268:Stimulation, Chemical; D014599:Uterus / Q000502:physiology*
D001337:Autonomic Agents; D012701:Serotonin; D010121:Oxytocin; D006632:Histamine; D000109:Acetylcholine; D009638:Norepinephrine; D004837:Epinephrine
Reactividad farmacológica del útero de hamster