title: Familial bilateral papillary cystadenoma of the epididymis: report of three cases in siblings.
abstract: This paper describes an unusual, familial bilateral papillary cystadenoma of the epididymis found in three siblings. The histological characteristics of the tumor were: 1) papillary proliferation of clear cells, consisting of both tall columnar and round ovoid cells, in the efferent duct epithelium; and 2) cystic dilatation of the duct with colloidal material. The present cases were unique in two respects: 1) familial bilateral papillary cystadenomas probably associated with Lindau's disease have not been reported previously: and 2) electron microscopic observations suggested that the tumors originated from the efferent duct.
mesh_terms: D000328:Adult; D003537:Cystadenoma / Q000235:genetics* / Q000473:pathology; D004822:Epididymis; D006801:Humans; D008297:Male; D010375:Pedigree; D013736:Testicular Neoplasms / Q000235:genetics* / Q000473:pathology; D006623:von Hippel-Lindau Disease / Q000150:complications