title: The effects of pre-exposure to scopolamine on subsequent drug state discrimination.
abstract: This experiment was done to test the prediction that preexposure to a drug state would increase the discriminability of that drug state when used as a cue in a discrimination task. Eight rats were pre-exposed to scopolamine for 20 days and 8 rats were given saline injections. The drug pre-exposed animals acquired a drug state discrimination more quickly than the controls. A difference was also found between the generalization gradients for each group with the pre-exposed group showing a steeper generalization gradient.
mesh_terms: D000818:Animals; D003463:Cues; D004193:Discrimination Learning / Q000187:drug effects*; D005795:Generalization, Stimulus / Q000187:drug effects*; D008297:Male; D051381:Rats; D012601:Scopolamine / Q000494:pharmacology*
chemical_list: D012601:Scopolamine