Evaluation of radioiodinated human serum albumin in the dog for assessment of hemodynamic function.
Radioiodinated human and dog serum albumins, each labeled with a different radioisotope of iodine (125I and 131I, respectively), were injected intravenously into dogs. Plasma volumes and plasma clearance half times were used for the comparative evaluation of the 2 radiopharmaceuticals. After repeated injections in a 6-week period, differences in these values could not be demonstrated. Plasma volumes obtained with both radioiodinated serum albumins compared favourably with the previously reported values in dogs.
D000818:Animals; D004285:Dogs / Q000502:physiology*; D006801:Humans; D012711:Serum Albumin, Radio-Iodinated / Q000032:analysis
D012711:Serum Albumin, Radio-Iodinated