Micellar effects upon the reaction of cobalt complexes with alkyl halides.
The reactions of the cobalozime Co (DH)-2 and the related Co(DOH)DOpn0 are strongly catalyzed by cationic micelles of cetyltrimethylammonium bromide (CTABr). The rate enhancements for the cobaloxime reaction and for that of Co (DOH)DOpn0 (in parentheses) are: EtBr approximately 1 (8.5); n-C5H11Cl, 220 (200); ClCH2CO-2, 420 (173); ClCH2CH2CO-2, 373. Anionic micelles of sodium lauryl sulfate inhibit the reaction of Co(DOH)DOpn0 with ClCH2CO-2, but do not affect that with n-C5H11Cl. The reactions of Co(DOH)DOpn0, like those of the cobaloxime are SN2 displacements and in the absence of surfactant in MeOH n-PrBr is more reactive than iso-PrBr.
D001665:Binding Sites; D002593:Cetrimonium Compounds; D003035:Cobalt; D003102:Colloids; D007700:Kinetics; D008823:Micelles; D008968:Molecular Conformation; D009942:Organometallic Compounds
D002593:Cetrimonium Compounds; D003102:Colloids; D008823:Micelles; D009942:Organometallic Compounds; D003035:Cobalt