[Acute myoglobinuria accompanied by renal failure in high febril infection (author's transl)].
A 41 year old man developed a myolysis with myoglobinuria during a period of high fever. The clinical signs were severe myalgia with general muscular weakness without manifest localized paresis. Electromyographically a diffuse generalized floride myopathy was found. Besides the extreme increase of CPK, a myoglobinuria was already macroscopically visible, which caused an acute renal failure. The treatment included corticosteroids and hemodialysis. An illness of several weaks was followed by complete recovery. As other known factors leading to myoglobinuria have been excluded, and the complement fixation reaction for Herpes simplex was more than 1:80, a viral-toxic etiology of this disease might be considered.
D058186:Acute Kidney Injury / Q000150:complications / Q000209:etiology*; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001799:Blood Sedimentation; D003168:Complement Fixation Tests; D004576:Electromyography; D005334:Fever; D006561:Herpes Simplex / Q000175:diagnosis; D006801:Humans; D008297:Male; D009135:Muscular Diseases / Q000209:etiology; D009212:Myoglobinuria / Q000150:complications / Q000209:etiology* / Q000628:therapy; D009431:Neural Conduction; D006435:Renal Dialysis; D012698:Serologic Tests; D014777:Virus Diseases / Q000150:complications*
D000305:Adrenal Cortex Hormones
Akute Myoglobinurie mit Nierenversagen bei hochfieberhaftem Infekt