Rapid TLC determination of methadyl acetate and some in vitro metabolites.
Methadyl acetate was metabolized by microsomal preparations of rat liver to yield nor-methadyl acetate and 6-(dimethylamino)-4,4-diphenyl-3-heptanol. The identification and separation of these three compounds was established by TLC, using iodoplatinate spray as a visualizing agent.
D000818:Animals; D002855:Chromatography, Thin Layer; D066298:In Vitro Techniques; D008297:Male; D008692:Methadyl Acetate / Q000031:analogs & derivatives / Q000032:analysis* / Q000378:metabolism; D008722:Methods; D008862:Microsomes, Liver / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D051381:Rats
D011506:Proteins; D008692:Methadyl Acetate