title: Memory performance after flurothyl treatment in rainbow trout.
abstract: Fingerling rainbow trout (N = 436) were trained in one trial with brief electric shock (2.0 V/cm) to suppress their spontaneous upstream swimming into a quiet well. Memory retention one day later was not influenced by the temperature at which they had been acclimated, trained and tested (10 degrees C, 15 degrees C or 20 degrees C). When exposed 4 min after training for 2 min, to a flurothyl solution (10, 25, 50, 100 or 200 mul/l) trout convulsed and overturned. The onset of overturn was concentration- and temperature-dependent. Flurothyl altered the one-day retention of avoidance behavior; low concentrations enhanced, whereas high concentrations impaired. Memory-enhancing low concentrations of flurothyl, applied after post-training amnesic treatment with carbon dioxide, reversed the carbon dioxide amnesia.
mesh_terms: D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects; D002245:Carbon Dioxide / Q000494:pharmacology; D004597:Electroshock; D005481:Flurothyl / Q000494:pharmacology*; D008568:Memory / Q000187:drug effects*; D012153:Retention, Psychology / Q000187:drug effects; D012487:Salmonidae; D012640:Seizures / Q000139:chemically induced; D013696:Temperature; D014337:Trout
chemical_list: D002245:Carbon Dioxide; D005481:Flurothyl