Formation of lipoperoxide in the retina of rabbit exposed to high concentration of oxygen.
When rabbit was exposed to high concentrations of oxygen, lipoperoxide in the retina was increased at 12 h of the exposure, after which period amplitude of electro-retinogram decreased. The degeneration was observed in the visual cell layer of the retina of the exposed animal. The exposure increased lipoperoxide in isolated retina. These data show the intervention of lipoperoxide in retinal degeneration by exposure to high concentration of oxygen.
D000818:Animals; D004596:Electroretinography; D050356:Lipid Metabolism; D010100:Oxygen / Q000494:pharmacology; D010545:Peroxides / Q000378:metabolism*; D011817:Rabbits; D012160:Retina / Q000187:drug effects* / Q000378:metabolism / Q000503:physiopathology; D012162:Retinal Degeneration / Q000139:chemically induced* / Q000503:physiopathology
D010545:Peroxides; D010100:Oxygen