title: Segmental renal vein renin assay and segmental nephrectomy for correction of renal hypertension.
abstract: Selective segmental renal vein catheterization was used to obtain venous blood samples for renin assay. With this technique a localized source of hypersecretion of renin was identified in 2 patients. Using samples from the main renal veins we found no significant difference in renin activity and, therefore, the etiology of the hypertension in these 2 patients would have been missed. Segmental nephrectomy resulted in a cure of the hypertension in both patients who were followed for a minimum of 14 months.
mesh_terms: D000293:Adolescent; D002404:Catheterization; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006977:Hypertension, Renal / Q000175:diagnosis* / Q000601:surgery; D009392:Nephrectomy; D012082:Renal Veins; D012083:Renin / Q000097:blood*
chemical_list: D012083:Renin