title: Ventilatory response to carbon dioxide in patients with homozygous sickle-cell disease.
abstract: The ventilatory response to carbon dioxide was measured by a rebreathing technique in 21 Nigerians who had homozygous sickle-cell disease. The slope of the carbon dioxide response curve was obtained by plotting the ventilation at successive half-minute intervals against the corresponding mean end-tidal PCO2. Our results showed that sickle-cell patients are as sensitive to carbon dioxide as are normal subjects.
mesh_terms: D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000503:physiopathology*; D002245:Carbon Dioxide / Q000032:analysis; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D012119:Respiration
chemical_list: D002245:Carbon Dioxide