Elastogenesis in healing wounds in bats.
Full-thickness square wounds were made in the webs of fruit bats. Elastin was laid down in the healing scars of these wounds in two forms--as single fibers under the regenerated epidermis, and as bundles of fine fibers taking their origin and orientation from the cut ends of the web elastin bundles. This process continued over a period of 6 months, during which time other components of the scar became reduced in amount. The arrangement of the new elastin in the scar tissue was thus a replica of that seen in the normal web. There are indications in this study that elastin imparts elasticity to the scar.
D000818:Animals; D002685:Chiroptera; D002921:Cicatrix / Q000473:pathology; D004195:Disease Models, Animal; D004549:Elastin / Q000096:biosynthesis / Q000502:physiology*; D012038:Regeneration; D012867:Skin / Q000648:ultrastructure; D012879:Skin Physiological Phenomena; D014945:Wound Healing; D014947:Wounds and Injuries / Q000473:pathology
D004549:Elastin