High incidence of ventricular septal defects in a family.
A family is described in which eight children, belonging to two sibships, had ventricular septal defects. The diagnoses were based on the clinical, radiological and ECG findings. The findings are compatible with a multifactorial mode of inheritance carrying a recurrence risk of 25 to 50%.
D000293:Adolescent; D002648:Child; D005260:Female; D005817:Genetic Counseling; D006345:Heart Septal Defects, Ventricular / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D008297:Male; D010375:Pedigree; D012306:Risk