Lysosomal enzyme levels in human amniotic fluid cells in tissue culture. IV. %A N-acetyl-beta-D-glucosaminidase.
Total and % A hexosaminidase were similar for primary cultures and later passages of amniotic fluid cells. The culture variables-through serial passage, within a passage and replicate primary cultures-resulted in some variation in total hexosaminidase, but an insignificant change in % A hexosaminidase. They are unlikely to give rise to any problems in the antenatal diagnosis of Sandhoff's and Tay-Sachs diseases.
D000118:Acetylglucosaminidase / Q000378:metabolism*; D000653:Amniotic Fluid / Q000166:cytology* / Q000201:enzymology; D002478:Cells, Cultured; D005260:Female; D006596:Hexosaminidases / Q000378:metabolism*; D006801:Humans; D008247:Lysosomes / Q000201:enzymology*; D011247:Pregnancy
D006596:Hexosaminidases; D000118:Acetylglucosaminidase