title: Artifacts in the centrifugation of ribosomal and heterogenous ribonucleic acid in "99%-dimethyl sulphoxide" gradients.
abstract: Increasing the total quantity of RNA located on 99%-dimethyl sulphoxide gradients profoundly altered the sedimentation pattern of heterogenous RNA and (to a smaller extent) that of rRNA. Aggregation of small quantities of rRNA with fast-sedimenting heterogenous RNA was also found to occur in these gradients.
mesh_terms: D002499:Centrifugation, Density Gradient; D012313:RNA / Q000032:analysis*; D012335:RNA, Ribosomal / Q000032:analysis; D013454:Sulfoxides
chemical_list: D012335:RNA, Ribosomal; D013454:Sulfoxides; D012313:RNA