Oxidation of 17-methylene steroids by thallium (III) and mercury (II) acetates.
The reaction of 17-methylene steroids with T1 (OAc)3 in hot AcOH results in the formation of a mixture of allylic compounds. Oxymercuration in t-BuOH followed by reductive demercuration affords 17-methylene-16beta -hydroxyderivatives as the major products.
D000731:Androstanes; D006571:Heterocyclic Compounds; D008628:Mercury; D010084:Oxidation-Reduction; D010126:Ozone; D011522:Protons; D013793:Thallium
D000731:Androstanes; D006571:Heterocyclic Compounds; D011522:Protons; D010126:Ozone; D013793:Thallium; D008628:Mercury