Hepatic porto-enterostomy or cholecystostomy in the treatment of extrahepatic biliary atresia. A study of 49 cases.
Hepatic porto-enterostomy or cholecystostomy (Kasai's procedure) was successful in restoring bile flow in 31 of 49 patients with "noncorrectable" extrahepatic biliary atresia.  However, all but one of the 31 developed acute or chronic complications such as cholangitis, bile peritonitis, or portal hypertension. During a five-year follow-up period, 26 (53%) died while 9 of the 23 survivors continue to manifest chronic or recurrent cholangitis. Thirteen of the 19 survivors who are more than one year of age have developed portal hypertension. These complications limit the prognosis of infants with "noncorrectable" biliary malformations.
D001652:Bile Ducts / Q000002:abnormalities* / Q000601:surgery; D002761:Cholangitis / Q000209:etiology; D005704:Gallbladder / Q000601:surgery*; D006801:Humans; D007223:Infant; D007422:Intestines / Q000601:surgery*; D008099:Liver / Q000601:surgery*; D008107:Liver Diseases / Q000209:etiology; D011183:Postoperative Complications; D018805:Sepsis / Q000209:etiology