[A clinical, électroéncephalographic and biochemical study of epileptic children and adolescents and their relatives].
The paper deals with the role of hereditary factors in the appearance of epilepsy by the aid of clinical, EEG and biochemical methods. The authors studied 35 children and adolescents with epilepsy and 69 of their relatives. In a EEG study fo the relatives of such patients there were 56% of changed curves, which indicate to an increased readiness of the brain to paroxysmal states. Besides, in the group of relatives where the children had epilepsy of an unknown nature the amount of changed curves was higher than that in the group of relatives where the patients had symptomatical epilepsy (62% and 51%). The biochemical data demonstrated some correlations between the bioelectrical brain activity with an increased amount of isoenzyme and LDH-I in the blood sera of relatives of epileptic patients.
D000293:Adolescent; D001921:Brain / Q000503:physiopathology; D002463:Cell Membrane Permeability; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis / Q000201:enzymology / Q000235:genetics* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
Klinicheskoe, élektroéntsefalograficheskoe i biokhimicheskoe izuchenie deteĭ i podrostkov, bol'nykh épilepsiĭ, i ikh rodstvennikov