Possible role of histamine receptors in cardiovascular responses to 5-hydroxytryptamine in the chicken.
Mepyramine (a selective H1-histamine receptor antagonist) and burimamide (a selective H2-receptor antagonist) specifically and equally modify the systemic hypotensive responses to both serotonin and histamine. Results suggest that both H1- and H2-histamine receptors in part mediate systemic arterial depressor and venous pressor responses to 5-HT in the domestic chicken.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D002049:Burimamide / Q000494:pharmacology; D002645:Chickens; D003864:Depression, Chemical; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006632:Histamine / Q000502:physiology*; D011738:Pyrilamine / Q000494:pharmacology; D011955:Receptors, Drug / Q000187:drug effects*; D012701:Serotonin / Q000494:pharmacology*
D011955:Receptors, Drug; D012701:Serotonin; D006632:Histamine; D011738:Pyrilamine; D000109:Acetylcholine; D002049:Burimamide