Behavioral correlates of focal hippocampal x-irradiation in rats.
A study presenting findings of focal hippocampal x-irradiation in early infancy and late behavior at two ages was carried out using Long-Evans hooded rats (Rattus norvegicus). Animals from eleven litters received 150-R irradiation treatments for 5  or 15 consecutive days and were then tested in an open field situation and in a two-way active avoidance apparatus. The results indicated that the behavioral deficits paralleled those seen in animals with classical hippocampal lesions. The results were offered in support of a response suppression model for hippocampal functioning.
D000367:Age Factors; D000818:Animals; D001362:Avoidance Learning / Q000528:radiation effects; D001522:Behavior, Animal / Q000528:radiation effects*; D006624:Hippocampus / Q000166:cytology / Q000502:physiology / Q000528:radiation effects*; D009474:Neurons / Q000528:radiation effects; D011830:Radiation Effects; D051381:Rats; D014965:X-Rays