[The existence of a thrombocyte refractory state].
The degree of ADP-induced platelet aggregation was considerably decreased during incubation of platelet-rich plasma with ADP. The data obtained showed that neither inhibitory action of the excess of adenosine, nor ADP breakdown in the plasma could account for this phenomenon. The results seem to indicate the significance of refractory state of platelets for the regulation of their aggregability.
D000244:Adenosine Diphosphate / Q000494:pharmacology*; D000818:Animals; D001792:Blood Platelets / Q000187:drug effects*; D010974:Platelet Aggregation; D011817:Rabbits
D000244:Adenosine Diphosphate
K voprosu o sushchestvovanii refraktornogo sostoianiia trombotsitov