Studies on the synergism of some hypotensive drugs with ethanol.
Synergism of some hypotensive drugs with ethanol was studied for its influence on the central nervous system. A very strong central action of the drugs and ethanol administered simultaneously in subthreshold doses was observed. Intensity of synergism was calculated by comparing the results with the effective doses of each drug administered seperately.
D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects; D003864:Depression, Chemical; D004357:Drug Synergism; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009048:Motor Skills / Q000187:drug effects; D013997:Time Factors
D000959:Antihypertensive Agents; D000431:Ethanol