title: [Regional myocardial perfusion on distribution through coronary drugs. I. Method of myocardial double radionuclide scintigraphy].
abstract: A methodical introduction of the measurement of regional myocardial microperfusion is given. Based on the results of selective coronary perfusion scintigraphy in this technique two isotopes are injected into the same coronary artery with a characteristic time interval between the two injections. The influence of the coronary active drug on regional myocardial microperfusion can be measured, when the second isotope is injected after a time interval corresponding to the maximum drug effect. The second isotope then marks the actual regional microperfusion under the influence of the drug. The two isotopes can be discriminated by their characteristic energy spectra and then quantitatively be compared. The scans are taken in different positions and then compared with the corresponding coronarograms and left ventriculograms.
mesh_terms: D000790:Angiocardiography; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000187:drug effects; D003331:Coronary Vessels; D011877:Radionuclide Imaging / Q000379:methods*; D013667:Technetium
chemical_list: D013667:Technetium
vernacular_title: Die regionale myokardiale Perfusionsumverteilung durch koronarwirksame Pharmaka. I. Methodik des myokardialen Doppelradionuklid-Szintigramms