Experimental studies on osmotic mechanisms and vegetative regulations of intraocular hydrodynamics as well as the distribution of elecrolytes and amino-acids in refractive environments of the eye.
The studies were carried out on the influence of hyperosmolar loading with glycerol and hypoosmotic glucose, as well as on the effect of pharmacological stimulation of the adrenergic system after sympathetic decentralization of the eyes, and of the cholinergic stimulation, on intraocular hydrodynamics, and on the distribution of electrolytes and amino-acids in refractive environments. The results showed a dependence between the changes in blood osmolality and osmotic intraocular activity, and the secretion and flow of the aqueous humor, as well as the distribution of electrolytes and amino-acids. No specific, antagonistic influence of the adrenergic and cholinergic stimulation on the hydrodynamics and the distribution of electrolytes and amino-acids in refractive environments has been found. The opposite reactions to stimulation of adrenergic alpha or beta-receptors have been observed.
D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D001082:Aqueous Humor / Q000378:metabolism; D002118:Calcium / Q000097:blood; D005123:Eye / Q000098:blood supply / Q000294:innervation / Q000378:metabolism*; D007429:Intraocular Pressure; D009995:Osmosis; D010275:Parasympathetic Nervous System / Q000502:physiology*; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood; D013564:Sympathetic Nervous System / Q000502:physiology*; D014822:Vitreous Body / Q000378:metabolism
D000596:Amino Acids; D012964:Sodium; D011188:Potassium; D002118:Calcium