The conversion of 3-Hydroxy-2,4,5-trihydroxymethylpyridine into pyridoxine by Kloeckera apiculata.
Kloeckera apiculata, a vitamin B-6-dependent yeast, grows in the presence of 3-hydroxy-2,4,5-trihydroxymethylpyridine in vitamin B-6-free media. On a molar basis the growth-promoting activity of this compound is approximately one-tenth that of other forms of vitamin B-6. [G-3H]3-Hydroxy-2,4,5-trihydroxymethylpyridine is converted into radioactive vitamin B-6 compounds of the same specific radioactivity by growing cultures of K. apiculata.
D011725:Pyridines / Q000138:chemical synthesis / Q000378:metabolism*; D011730:Pyridoxal / Q000032:analysis; D011733:Pyridoxamine / Q000032:analysis; D011735:Pyridoxic Acid / Q000032:analysis; D011736:Pyridoxine / Q000032:analysis / Q000096:biosynthesis*; D015003:Yeasts / Q000254:growth & development / Q000378:metabolism*
D011725:Pyridines; C012377:3-hydroxy-2,4,5-trihydroxymethylpyridine; D011730:Pyridoxal; D011735:Pyridoxic Acid; D011733:Pyridoxamine; D011736:Pyridoxine