[Urinary aldosterone excretion and erythrocyte and plasma sodium and potassium ion concentration in persons of different ages].
Practically healthy persons (79 in all) aged from 20 to 80 years and over were examined. The work was aimed at the study of the character of aldosterone excretion and its correlation with the ionic composition of erythrocytes and the peripheral blood plasma in persons at various age periods. As revealed, the activity of glomerular zone of the adrenal cortex in persons aged from 20 to 40 years displayed sexual differences: 1.33 times more aldosterone was excreted with the urine in women than in men. With the advance of age there occurred a functional decrease in the glomerular zone of the adrenal cortex. In senile persons (aged 80 years and over) this difference was entirely eliminated. Sodium ions in erythrocytes increased, but remained unchanged in the peripheral blood plasma. Potassium ion concentration fell both in the erythrocytes and in the blood plasma. A reduction of aldosterone content failed to alter the sodium-retention effect of its action which corresponded to the concept on increase of tissue sensitivity to hormones with the advance of age.
D000302:Adrenal Cortex / Q000502:physiology*; D000311:Adrenal Glands / Q000502:physiology*; D000368:Aged; D000375:Aging; D000450:Aldosterone / Q000652:urine*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000097:blood*; D012964:Sodium / Q000097:blood*
D000450:Aldosterone; D012964:Sodium; D011188:Potassium
Vydelenie al'dosterona s mochoĭ i soderzhanie ionov kaliia i natriia v éritrotsitakh i plazme krovi u liudeĭ raznogo vozrasta