Synthesis of 5-hydroxy-1-((5-(p-nitrophenyl)furfurylidene)-amino) hydantoin, a metabolite of dantrolene.
The synthesis and structural elucidation of 5-hydroxyl-1-[[5-(p-nitrophenyl)furfurylidene]amino]hydantoin, a compound proposed as a metabolite of dantrolene sodium, are reported. In addition, a chromatographic comparison of the biological and synthesized materials is made.
D003620:Dantrolene / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism; D006827:Hydantoins / Q000031:analogs & derivatives*; D008722:Methods
D006827:Hydantoins; D003620:Dantrolene