Sensorimotor polyneuropathy and monoclonal IgM: a review of clinical and immunological features.
Main clinical and biological features of peripheral neuropathies associated with monoclonal IgM are reviewed. Special emphasis is given to the structure of these monoclonal auto-antibodies which points to an antigen (or some other kind of selective pressure) driven process.
D000595:Amino Acid Sequence; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity / Q000276:immunology; D001323:Autoantibodies / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology*; D008969:Molecular Sequence Data; D009185:Myelin Proteins / Q000276:immunology; D018992:Myelin-Associated Glycoprotein; D010523:Peripheral Nervous System Diseases / Q000276:immunology*; D015995:Prevalence
D000911:Antibodies, Monoclonal; D001323:Autoantibodies; D007075:Immunoglobulin M; D009185:Myelin Proteins; D018992:Myelin-Associated Glycoprotein