Antigenicity of licensed whole virion and subvirion influenza vaccines in "high risk" persons.
The frequency and magnitude of serum antibody response to type A and B influenza virus induced by whole virion and subvirion vaccines were essentially comparable. Immunization was followed in vaccinated individuals by an antihemagglutinin antibody response to the common antigenic determinant shared by the type A H3N2 viruses. Relatively few individuals developed antibody to the type-specific determinant.
D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000096:biosynthesis*; D000918:Antibody Specificity; D000956:Antigens, Viral; D006801:Humans; D009980:Influenza A virus / Q000276:immunology; D007252:Influenza Vaccines; D008875:Middle Aged; D009975:Orthomyxoviridae / Q000276:immunology*
D000914:Antibodies, Viral; D000956:Antigens, Viral; D007252:Influenza Vaccines