[Vasopressin concentration in the blood and sensitivity of the cardiovascular system to it during aging].
With aging the content of the blood vasopressin increases. In old animals smaller doses of vasopressin induce coronary insufficiency (rise of T wave, shift of S-T segment, disorders of the atrio-ventricular conductivity). On continuous administration of vasopressin (during a month), arterial hypertension appears only in old animals due to increase in cardiac output, stroke volume at unchanged cardiac rhythm, and to some decrease in the total peripheral resistance.
D000328:Adult; D000368:Aged; D000375:Aging; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects*; D006329:Heart Conduction System / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D011817:Rabbits; D014655:Vascular Resistance / Q000187:drug effects; D014667:Vasopressins / Q000097:blood* / Q000494:pharmacology
D014667:Vasopressins
Soderzhanie vazopressina v krovi i chuvstvitel'nost' k nemu serdechno-sosudistoĭ sistemy pri starenii