Bacterial prostatitis: treatment with trimethoprim-sulfamethoxazole.
Fifteen patients with chronic bacterial prostatitis were treated with trimethoprim-sulfamethoxazole for three months. In 60 per cent of the patients a recurrence of chronic bacterial prostatitis developed during a follow-up period of from one to two and one-half years. It appears that factors other than a diffusion barrier to effective antimicrobial agents into the prostatic gland are responsible for the persistence of chronic bacterial infections of the prostate.
D001424:Bacterial Infections / Q000188:drug therapy*; D004338:Drug Combinations; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011472:Prostatitis / Q000188:drug therapy*; D012008:Recurrence; D013420:Sulfamethoxazole / Q000627:therapeutic use*; D014295:Trimethoprim / Q000627:therapeutic use*
D004338:Drug Combinations; D014295:Trimethoprim; D013420:Sulfamethoxazole