[The functional heterogeneity of the synapses of the frog sartorius muscle].
Three main types of neuro-muscular junctions were revealed by means of the e.p.p. quantum content and the e.p.p. dynamics during high-frequency stimulation. Heterogeneity of synaptic apparatus seems to be mainly due to different intensities of quantum release. Subctances facilitating neuro-muscular transmission (Ca2+ ions, imidazol) were more effective in myoneural junctions with low e.p.p. quantum content, while depressing chemical agents (acetylcholine, tubocurarine) exerted a more potent effect in junctions with high quantum content.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D002118:Calcium / Q000494:pharmacology; D007093:Imidazoles / Q000494:pharmacology; D008564:Membrane Potentials / Q000187:drug effects*; D009469:Neuromuscular Junction / Q000502:physiology*; D014403:Tubocurarine / Q000494:pharmacology
D007093:Imidazoles; D000109:Acetylcholine; D002118:Calcium; D014403:Tubocurarine
Funktsional'naia neodnorodnost' sinapticheskikh priborov portniazhnoĭ myshtsy liagushki