The determination of the binding constant of metalloenzymes for their active site metal ion from ligand inhibition data. Theoretical analysis and application to the inhibition of thermolysin by 1,10-phenanthroline.
D001665:Binding Sites; D055598:Chemical Phenomena; D002621:Chemistry; D004791:Enzyme Inhibitors; D004798:Enzymes; D008024:Ligands; D008667:Metalloproteins; D008670:Metals; D008956:Models, Chemical; D010618:Phenanthrolines; D013820:Thermolysin / Q000037:antagonists & inhibitors; D015032:Zinc
D004791:Enzyme Inhibitors; D004798:Enzymes; D008024:Ligands; D008667:Metalloproteins; D008670:Metals; D010618:Phenanthrolines; D013820:Thermolysin; D015032:Zinc