[Correlation between immunological stage and response to chemotherapy. Results in 64 patients with nonresectable epidermoid bronchial cancers].
Out of 64 patients with non resectable epidermal bronchus carcinoma, 26 patients had before any treatment positive responses of skin tests to recall antigens. In these patients we found a correlation between the reactivity of the skin tests, the presence of seric factor inhibiting the leucocyte migration, the mean count of peripheral lymphocytes and the response to combination chemotherapy protocol. The patients who respond to treatment have a significantly better prognosis than the patients who do not respond. With this correlation it seems to be possible to distinguish between two populations of patients with non resectable bronchus carcinoma : one population with a good risk who can be significantly improved by the treatment : the other population with a very severe prognosis.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D001772:Blood Cell Count; D001984:Bronchial Neoplasms / Q000188:drug therapy / Q000276:immunology*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000276:immunology*; D002464:Cell Migration Inhibition; D004137:Dinitrochlorobenzene; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed; D007962:Leukocytes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000276:immunology; D011379:Prognosis; D012882:Skin Tests
D000305:Adrenal Cortex Hormones; D004137:Dinitrochlorobenzene
Relation entre l'état immunitaire et la réponse à la chimiothérapie. Résultats chez 64 malades avec cancers bronchiques épidermoïdes inopérables