[Gougerot-Sjögren syndrome in patients with sarcoidosis].
Three patients with eye and salivary dryness presenting the scintigraphic and histological features of Sjogren's syndrome and also suffering from sarcoïdosis, are reported. The authors stress the rarity of clinically indentifiable dry oculo-salivary syndromes whilst routine scintigraphy of the principle salivary glands using technetium 99 m often reveals altered salivary function. They consider that the primary feature in the development of this dry salivary syndrome consists of fibro-inflammatory lesions of the glandular interstitium, seen in specimens of the glands of the labial mucosae, which are sequelae of the initial sarcoid infiltration. They point out that Sjogren's syndrome occurring in relation with sarcoïdosis has certain special features. These include its appearance in relatively young subjects, the minimal symptoms, the non-essential presence of inflammatory signs and the absence of associated connective tissue disorder.
D000328:Adult; D000367:Age Factors; D001706:Biopsy; D005260:Female; D006099:Granuloma; D006801:Humans; D007765:Lacrimal Apparatus / Q000378:metabolism; D008214:Lymphocytes; D008297:Male; D008875:Middle Aged; D010950:Plasma Cells; D011877:Radionuclide Imaging; D012469:Salivary Glands / Q000378:metabolism / Q000473:pathology; D012507:Sarcoidosis / Q000150:complications* / Q000473:pathology; D012598:Sclerosis; D012859:Sjogren's Syndrome / Q000175:diagnosis / Q000209:etiology*; D013667:Technetium
D013667:Technetium
Syndrome de Gougerot-Sjögren chez les sujets atteints de sarcoïdose