title: A possible mechanism for concentrating sodium and potassium in the cell nucleus.
abstract: A dynamic, nonequilibrium mechanism is proposed for concentrating both Na+ and K+ in the cell nucleus. The model is consistent with experiment observations and with known properties of cell membranes. This model could explaing the high nucleoplasm to cytoplasm ratios of Na+ and/or K+ reported for liver kidney, thymus, frog skin, ascites cells, and amphibian oocytes.
mesh_terms: D000818:Animals; D001202:Ascitic Fluid / Q000378:metabolism; D001693:Biological Transport, Active; D002462:Cell Membrane / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism*; D003593:Cytoplasm / Q000378:metabolism; D004735:Energy Transfer; D005260:Female; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008722:Methods; D008954:Models, Biological; D009865:Oocytes / Q000378:metabolism; D009928:Organ Specificity; D011188:Potassium / Q000378:metabolism*; D012867:Skin / Q000378:metabolism; D012964:Sodium / Q000378:metabolism*; D013950:Thymus Gland / Q000378:metabolism
chemical_list: D012964:Sodium; D011188:Potassium