title: Infrared identification of maleic acid in pharmaceutical maleate salts.
abstract: Difficulties are encountered in the USP melting point identification test for maleic acid extracted from chlorpheniramine maleate. A general procedure is described for the isolation and infrared identification of the maleic acid moiety of pharmaceutical salts from drug substances or dosage forms. This procedure permits the concurrent infrared identification of the amine moiety.
mesh_terms: D000588:Amines / Q000032:analysis; D002744:Chlorpheniramine / Q000032:analysis*; D004304:Dosage Forms; D008298:Maleates / Q000032:analysis*; D013055:Spectrophotometry, Infrared; D013607:Tablets / Q000032:analysis
chemical_list: D000588:Amines; D004304:Dosage Forms; D008298:Maleates; D013607:Tablets; D002744:Chlorpheniramine