Toxicological studies of photosensitizer agents and photodegradable polyolefins.
The authors report the results of a series of toxicological tests conducted on plastic materials (polyethylene) activated with tetraphenylbutadiene (TPB) an additive recently proposed as a sensitizer capable of photodegrading plastic materials. The toxic effects of polyethylene, TPB, and TPB's degradation products were investigated in rabbits, mice and rats. The studies revealed these products to possess a very low toxicity.
D000818:Animals; D002070:Butadienes / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000633:toxicity; D004343:Drug Implants; D005123:Eye / Q000187:drug effects; D006099:Granuloma / Q000139:chemically induced; D006439:Hemodynamics / Q000187:drug effects; D007509:Irritants / Q000494:pharmacology; D007928:Lethal Dose 50; D008027:Light; D008297:Male; D051379:Mice; D010782:Photolysis; D011095:Polyethylenes / Q000633:toxicity*; D051381:Rats
D002070:Butadienes; D004343:Drug Implants; D007509:Irritants; D011095:Polyethylenes