Azidomorphine: subjective effects and suppression of morphine abstinence.
In man, azidomorphine, a new morphine congener, constricted pupils, produced morphine-like subjective effects and euphoria, and suppressed the morphine abstinence syndrome. Azidomorphine was 10 to 50 times as potent as morphine. It is concluded that in man azidomorphine is a typical morphine-like drug.
D001386:Azides / Q000627:therapeutic use; D005059:Euphoria; D006801:Humans; D008916:Miotics; D009021:Morphine Dependence / Q000503:physiopathology*; D009022:Morphine Derivatives / Q000494:pharmacology / Q000627:therapeutic use*; D010919:Placebos; D011680:Pupil / Q000187:drug effects; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy*; D013997:Time Factors
D001386:Azides; D008916:Miotics; D009022:Morphine Derivatives; D010919:Placebos