[The effect of an inhibitor of erythropoiesis on the metabolism of tissues of various organs].
The nucleus of the bone marrow cells was shown to be the source of humoral inhibitor of erythropoiesis and to inhibit the oxidative metabolism in the bone marrow. However, the nucleus intensifies aerobic oxidative metabolism in the kidneys. Therefore the nucleus of the bone marrow cells was suggested to regulate the formation of erythropoietin in the kidneys.
D000818:Animals; D001853:Bone Marrow / Q000032:analysis* / Q000187:drug effects* / Q000201:enzymology / Q000648:ultrastructure; D001854:Bone Marrow Cells; D003864:Depression, Chemical; D004920:Erythropoiesis / Q000187:drug effects*; D007527:Isoenzymes / Q000378:metabolism; D007668:Kidney / Q000187:drug effects* / Q000201:enzymology; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008291:Malate Dehydrogenase / Q000378:metabolism; D011817:Rabbits
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D008291:Malate Dehydrogenase
O vliianii ingibitora éritropoéza na metabolizm tkaneĭ nektorykh organov