[The immediate and late results of treating patients with nonspecific lung diseases by using the local administration of kontrikal and antibiotics].
An analysis was made of the short- and long-term (1.5-2 years) results of the treatment of 75 patients with acute abscess and 101 with lingering pneumonia using different routes of administration of proteinase inhibitors and antibiotics. The high efficacy was demonstrated of the local intrapulmonary and endobronchial administration of the proteinase inhibitor contrykal and antibiotics. The treatment method suggested was found to compare favourably with the common route of the drug administration. The treatment is well tolerated and promotes the shortening of the times of the patients' stay in the hospital, reduces the number of complications and residual phenomena, prevents the disease relapses and their transformation to chronic nonspecific pulmonary diseases. The clinical recovery of the patients with acute lung abscess was reached in 91.4% of cases whereas in the reference group, only in 66.7%. In the patients with lingering pneumonia, the recovery was noted in 85.4%, in the reference group, in 27.5% of cases.
D000208:Acute Disease; D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D007611:Aprotinin / Q000008:administration & dosage*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D006801:Humans; D007277:Injections, Jet; D008169:Lung Abscess / Q000188:drug therapy; D008171:Lung Diseases / Q000188:drug therapy*; D011014:Pneumonia / Q000188:drug therapy; D012074:Remission Induction
D000900:Anti-Bacterial Agents; D007611:Aprotinin
Blizhaĭshie i otdalennye rezul'taty lecheniia bol'nykh nespetsificheskimi zabolevaniiami legkikh s primeneniem mestnogo vvedeniia kontrikala i antibiotikov.