Effect of ovarian sex hormones on the pool of free amino acids in maternal tissues of pregnant rats fed a protein-free diet.
The effects of s.c. injections of 5 mug oestrone/kg and 50 mg progesterone/kg on Days 5-7 of gestation were investigated in rats fed a protein-free diet. The decrease in essential and non-essential amino acid concentrations in maternal liver and the implantation site caused by dietary protein deficiency was restored to control values, whereas the alterations of the plasma free amino acid concentrations, except for arginine and glycine, were not reversed by hormone treatment.
D000596:Amino Acids / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004032:Diet; D004970:Estrone / Q000494:pharmacology*; D005260:Female; D008099:Liver / Q000378:metabolism; D009929:Organ Size / Q000187:drug effects; D011247:Pregnancy; D011248:Pregnancy Complications / Q000378:metabolism*; D011374:Progesterone / Q000494:pharmacology*; D011488:Protein Deficiency / Q000378:metabolism*; D051381:Rats; D014599:Uterus / Q000378:metabolism
D000596:Amino Acids; D004970:Estrone; D011374:Progesterone