Analysis of internal proteins of influenza A (H2N2) viruses isolated from birds in East Germany in 1983.
Proteins and RNAs of influenza A (H2N2) viruses isolated from birds in 1983 in East Germany were compared antigenically with those of H2N2 human strains. The electrophoretic mobility of the viral proteins and of the S1-treated double-stranded RNAs from two human and six avian strains, as well as the results of EIA-tests using monoclonal antibodies to their matrix protein and nucleoproteins indicate an antigenic relationship between the avian isolates and human strains of H2N2 subtype. One of the avian strains had a reduced amount of matrix protein.
D000818:Animals; D000911:Antibodies, Monoclonal; D000956:Antigens, Viral / Q000032:analysis*; D004372:Ducks; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes / Q000032:analysis*; D005859:Germany, East; D006801:Humans; D053121:Influenza A Virus, H2N2 Subtype; D009980:Influenza A virus / Q000737:chemistry*; D012367:RNA, Viral / Q000032:analysis*; D014763:Viral Matrix Proteins / Q000032:analysis*
D000911:Antibodies, Monoclonal; D000956:Antigens, Viral; D000939:Epitopes; D012367:RNA, Viral; D014763:Viral Matrix Proteins