title: Influence of aging upon the urinary hormone excretion in the male.
abstract: The urinary excretion of LH, low polar oestrogens, neutral C19 and C21 steroids was measured in normal healthy males aged 20-79 years. No significant changes could be noted for the excretion of LH, pregnanediol and 17-ketogenic steroids between 50 and 79 years. The excretion of androsterone and aeticholanolone was significantly lower in the oldest group (70-79 years). A significant drop in the excretion of DHA was noted at approx. 60 years. The excretion of low polar oestrogens remained constant from 20 to 55-59 years, but showed a highly significant (P less than 0.001) decrease at about 60 years. This drop might reflect a sudden decrease in the plasma levels of oestrone sulphate due to a decreased sulphurylating activity in the liver.
mesh_terms: D015068:17-Ketosteroids / Q000652:urine*; D000328:Adult; D000368:Aged; D000375:Aging; D000738:Androsterone / Q000652:urine; D004970:Estrone / Q000652:urine; D005043:Etiocholanolone / Q000652:urine; D012739:Gonadal Steroid Hormones / Q000652:urine*; D006801:Humans; D007986:Luteinizing Hormone / Q000652:urine*; D008297:Male; D008875:Middle Aged; D011276:Pregnanediol / Q000652:urine
chemical_list: D015068:17-Ketosteroids; D012739:Gonadal Steroid Hormones; D004970:Estrone; D007986:Luteinizing Hormone; D005043:Etiocholanolone; D000738:Androsterone; D011276:Pregnanediol