title: Sporozoites of Eimeria acervulina within intestinal macrophages in normal experimental infections: an ultrastructural study.
abstract: Sporozoites of Eimeria acervulina were observed in macrophages of the intestinal epithelium 5 and 6 days post-infection. These sporozoites lay within a well developed parasitophorous vacuole, were normal in structure and showed no signs of development. Macrophages harbouring sporozoites showed considerable structural changes, most pronounced being an absence of lysosomes, an enlarged nucleolus and extensive proliferation of the Golgi complex and endoplasmic reticulum. Possible mechanisms of survival and transport of sporozoites to preferred sites of development are discussed.
mesh_terms: D000818:Animals; D002645:Chickens; D003048:Coccidiosis / Q000473:pathology*; D004539:Eimeria / Q000648:ultrastructure*; D007413:Intestinal Mucosa / Q000469:parasitology*; D008264:Macrophages / Q000469:parasitology* / Q000648:ultrastructure; D008297:Male