Influence of "thickening" agents on the antidotal efficacy of activated charcoal.
The addition of "thickening" agents such as bentonite and carboxymethylcellulose to activated charcoal slurries considerably improves the palatability of this antidote yet does not reduce the efficacy of the activated charcoal in reducing the gastrointestinal absorption of aspirin. Flavoring of such preparations may further enhance this palatability.
D000328:Adult; D001546:Bentonite / Q000494:pharmacology*; D002266:Carboxymethylcellulose Sodium / Q000494:pharmacology*; D002606:Charcoal / Q000494:pharmacology*; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects*; D008297:Male; D008747:Methylcellulose / Q000031:analogs & derivatives*; D012459:Salicylates / Q000378:metabolism / Q000652:urine
D012459:Salicylates; D001546:Bentonite; D002606:Charcoal; D008747:Methylcellulose; D002266:Carboxymethylcellulose Sodium