title: Synthesis of 2'-acetoxybiphenyl-2-carboxylic acid and its derivatives as potential anti-inflammatory and analgesic agents.
abstract: 2'-Acetoxybiphenyl-2-carboxylic acid and a series of derivatives were synthesized. The title compound and its unsubstituted amide had both anti-inflammatory and analgesic properties. Its aminoethyl esters exhibited only analgesia. None of the compounds showed any significant antimicrobial activity.
mesh_terms: D000700:Analgesics / Q000138:chemical synthesis* / Q000627:therapeutic use; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis* / Q000627:therapeutic use; D001713:Biphenyl Compounds / Q000138:chemical synthesis* / Q000627:therapeutic use; D051381:Rats
chemical_list: D000700:Analgesics; D000893:Anti-Inflammatory Agents; D001713:Biphenyl Compounds