Phenobarbital and SKF-525A on vinblastine and vincristine toxicity in mice.
The effect of SKF-525A and phenobarbital on the LD50 values of vinblastine and vincristine suggests that the toxicity of these agents in mice does not arise from a toxic metabolite.
D000818:Animals; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D010634:Phenobarbital / Q000494:pharmacology*; D011335:Proadifen / Q000494:pharmacology*; D014747:Vinblastine / Q000633:toxicity*; D014750:Vincristine / Q000633:toxicity*
D014750:Vincristine; D014747:Vinblastine; D011335:Proadifen; D010634:Phenobarbital