Multinucleated giant cells in antiglomerular basement membrane antibody-induced glomerulonephritis.
Inflammatory giant cells were found in close association with glomerular basement membrane in a case of rapidly progressive glomerulonephritis. It is suggested that this finding is due to an alteration in properties of the glomerular basement membrane most probably brought about by circulating antibody to basement membrane.
D000208:Acute Disease; D000328:Adult; D000906:Antibodies; D001485:Basement Membrane / Q000276:immunology / Q000473:pathology; D005921:Glomerulonephritis / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007678:Kidney Glomerulus / Q000276:immunology / Q000473:pathology*; D008297:Male; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence
D000906:Antibodies