Plasma renin activity in abortion.
Healthy women (N = 96) were investigated for changes in plasma renin activity (PRA) in abortion. In spontaneous abortion PRA levels were significantly lower than in induced abortion although higher than in healthy women. These findings may be explained by differences in corpus luteum function and renin production of the feto-placental unit. Alternatively, prostaglandins, released by the contracting uterus in spontaneous abortion may cause PRA suppression, as observed in 9 pregnant women with abortion induced by the intra-amniotic use of prostaglandin F2alpha.
D000028:Abortion, Induced; D000022:Abortion, Spontaneous / Q000097:blood*; D000033:Abortion, Threatened / Q000097:blood; D000293:Adolescent; D005260:Female; D006801:Humans; D011247:Pregnancy; D011460:Prostaglandins F; D012083:Renin / Q000097:blood*
D011460:Prostaglandins F; D012083:Renin