Efficacy of p-Toluoyl chloride phenylhydrazone against gastrointestinal helminths in ovines.
A new anthelmintic candidate, p-toluoyl chloride phenlylhydrazone, was administered to lambs in a paste formulation. The efficacy of this drug was determined at dose rates of 20, 30, 40, and 50 mg of active ingredient per kilogram of body weight. Helminths expelled by these dosages included Haemonchus contortus, Ostertagia circumcicta, Trichostrongylus colubriformis, T. axei, Nematodirus filicollis, Cooperia curticei, Strongyloides papillosus, Oesophagostomum columbianum, Bunostomum trigoncephalum, Chabertia ovina, Moniezia expansa, and M. benedeni.
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D001565:Benzoates / Q000627:therapeutic use*; D006188:Haemonchiasis / Q000188:drug therapy / Q000662:veterinary; D006374:Helminthiasis, Animal; D006835:Hydrazones / Q000627:therapeutic use*; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000662:veterinary*; D008989:Monieziasis / Q000188:drug therapy; D009814:Oesophagostomiasis / Q000188:drug therapy / Q000662:veterinary; D010029:Ostertagiasis / Q000188:drug therapy / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy*; D013272:Stomach Diseases / Q000188:drug therapy / Q000662:veterinary*; D014252:Trichostrongyloidiasis / Q000188:drug therapy / Q000662:veterinary
D000871:Anthelmintics; D001565:Benzoates; D006835:Hydrazones; C012583:4-toluoyl chloride phenylhydrazone