title: Reversible unilateral lens opacities in a diabetic patient.
abstract: Following one month of poor diabetic control, a 54-year-old patient presented with a unilateral posterior subcapsular cataract, consisting of numerous fine, feathery, streak-like opacities radiating from a dense, round, central, posterior, subcapsular plaque. Except for extensive pseudoexfoliation, the fellow lens was clear. After a subsequent week of strict diabetic control, the feathery streak-like opacities had almost disappeared. The findings are discussed in relation to the experimentally induced sugar cataract in which sugar alcohol accumulation and subsequent lens swelling result in a potentially reversible lens opacification.
mesh_terms: D001786:Blood Glucose; D002386:Cataract / Q000139:chemically induced / Q000209:etiology*; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000628:therapy; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010507:Periodicity; D012075:Remission, Spontaneous; D013402:Sugar Alcohols; D014044:Tolbutamide / Q000627:therapeutic use; D014792:Visual Acuity
chemical_list: D001786:Blood Glucose; D007328:Insulin; D013402:Sugar Alcohols; D014044:Tolbutamide