title: [Intragastric titration, a method for clinically testing the effect of antacids].
abstract: Intragastric titration can be used not only for the quantiative assessment of gastric secretion in healthy subjects and patients with peptic ulcer, but also for differentiating disorders in the regulation of HCI secretion. It is useful foe evaluating the effect of antacids after stimulation of acid secretion with  a test meal. The duration of action of an antacid taken about one hour after a meal was much greater than when taken on an empty stomach. Results in 12 healthy subjects indicate that frequent small meals (6 to 8 daily) and antacids between meals greatly reduce gastric acidity. Whether these findings hold true for patients with peptic ulcer remains to be determined.
mesh_terms: D000328:Adult; D000863:Antacids / Q000592:standards*; D004381:Duodenal Ulcer / Q000175:diagnosis; D005260:Female; D005745:Gastric Acidity Determination / Q000379:methods*; D006801:Humans; D008297:Male; D009747:Nutritional Physiological Phenomena; D013997:Time Factors
chemical_list: D000863:Antacids
vernacular_title: Intragastrale Titration. Eine Methode zur klinischen Testung von Antacida