Failure of amygdalin to arrest B16 melanoma and BW5147 AKR leukemia.
Parenteral amygdalin was found to be ineffective in C57BL/6 mice with B16 melanoma and in AKR mice with BW5147 lymphatic leukemia, in doses ranging from 50 to 5000 mg/kg.
D000678:Amygdalin / Q000494:pharmacology / Q000627:therapeutic use*; D000818:Animals; D005260:Female; D007942:Leukemia, Experimental / Q000188:drug therapy* / Q000209:etiology; D008545:Melanoma / Q000188:drug therapy* / Q000209:etiology; D008558:Melphalan / Q000627:therapeutic use; D051379:Mice; D008806:Mice, Inbred AKR; D008810:Mice, Inbred C57BL; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000209:etiology; D009570:Nitriles / Q000627:therapeutic use*
D009570:Nitriles; D000678:Amygdalin; D008558:Melphalan