[Changes in resistance to the tumor process subserved by the presence of a focus of tuberculosis mycobacteria in the lungs].
Tumours were induced in rats with the aid of 20-methylcholantrene. Preliminary (11 to 13 days before) administration into the lung tissue of Mycobacteria tuberculosis in the composition of the water-oil emulsion decreased the animal resistance to the tumour origination. This effect is supposed to be caused by an intensification of the autoimmune processes as a result of mycobacteria administration.
D000818:Animals; D001323:Autoantibodies; D005260:Female; D005620:Freund's Adjuvant; D008297:Male; D008748:Methylcholanthrene; D009374:Neoplasms, Experimental / Q000139:chemically induced* / Q000276:immunology; D051381:Rats; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000276:immunology
D001323:Autoantibodies; D008748:Methylcholanthrene; D005620:Freund's Adjuvant
Izmeneniia rezistentnosti k opukholevomu protsessu, obuslovlennye nalichiem ochaga tuberkuleznykh mikobakteriĭ v legkikh