[Changes in the electrical properties of atrial trabecula induced by an electric stimulus].
Electrical activity, excitation threshold and "steady--state" current-voltage, relationship (estimated under voltage clamp conditions) in the membrane of chicken embryo atrial trabecula were investigated by means of double succrose-gap technique. Application of short (10 msec) electrical stimuli with magnitudes up to 6.10(-5) a (1-150 threshold) resulted in increased excitability and appearance of spontaneous activity. Release of neurotransmitters and polarity of the applied sitmulus are shown not to play a significant role in the changes in membrane excitability observed, the main cause of the latter being the increased sodium permeability of the membrane.
D000818:Animals; D016275:Atrial Function; D001285:Atropine / Q000494:pharmacology; D002642:Chick Embryo; D004558:Electric Stimulation; D004594:Electrophysiology; D006325:Heart Atria / Q000187:drug effects; D066298:In Vitro Techniques; D011433:Propranolol / Q000494:pharmacology
D001285:Atropine; D011433:Propranolol
Izmeneniia élektricheskikh svoĭstv trabekuly predserdiia, vyzvannye élektricheskim stimulom