title: [The dynamics of serotonin in tissues in acute hypoxia (the phenomenon and its possible significance].
abstract: Serotonin (5HT) decreased in the bone marrow and renal cortex, and hyperserotoninemia developed immediately after one-hour hypoxia. Six-hour hypoxia was followed by an additional decrease of 5-HT in the kidney, medulla, spleen and thymus. Phasic changes of the 5-HT TOOK PLACE at the posthypoxic period. Apparently hypoxia led to the 5-HT mobilization and an increase of its biosynthesis. A possible significance of the 5-HT for the control of hemopoiesis both at the level of the kidney and directly al the level of hemopoietic cells is discussed.
mesh_terms: D000208:Acute Disease; D000818:Animals; D001853:Bone Marrow / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D005260:Female; D000860:Hypoxia / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism; D007672:Kidney Cortex / Q000378:metabolism; D007679:Kidney Medulla / Q000378:metabolism; D008198:Lymph Nodes / Q000378:metabolism; D051379:Mice; D008808:Mice, Inbred CBA; D012701:Serotonin / Q000378:metabolism*; D013154:Spleen / Q000378:metabolism; D013950:Thymus Gland / Q000378:metabolism
chemical_list: D012701:Serotonin
vernacular_title: Dinamika serotonina v tkaniakh pri ostroĭ gipoksii (fenomen i ego vozmozhnoe znachenie)