Selecting chemotherapy for metastatic breast cancer.
When cytotoxic chemotherapy is indicated in metastatic breast cancer, usually a combination of an alkylating agent and an antimetabolite, with or without doxorubicin, is used. The combinations including doxorubicin appear to give the best response rate.
D000368:Aged; D000477:Alkylating Agents / Q000627:therapeutic use*; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001500:BCG Vaccine / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy; D004317:Doxorubicin / Q000009:adverse effects / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis / Q000188:drug therapy*; D010386:Pelvic Neoplasms / Q000628:therapy; D013125:Spinal Neoplasms / Q000532:radiotherapy / Q000628:therapy; D013921:Thrombocytopenia / Q000139:chemically induced
D000477:Alkylating Agents; D000964:Antimetabolites, Antineoplastic; D001500:BCG Vaccine; D004317:Doxorubicin