title: Shy-Drager syndrome with abnormal respirations and antidiuretic hormone release.
abstract: A patient with Shy-Drager syndrome exhibited a partial defect in antidiuretic hormone (ADH) release, and cluster breathing, an indication of pontomedullary respiratory center damage, with a normal CO2 response curve. This extends the spectrum of abnormalities associated with the degenerative disease of the central nervous system. The presence of a pontomedullary respiratory pattern without an impaired CO2 response curve suggests that neurons that determine respiratory rhythm function independently from those that function as chemoreceptors.
mesh_terms: D001049:Apnea / Q000209:etiology; D001794:Blood Pressure; D002245:Carbon Dioxide / Q000378:metabolism; D002493:Central Nervous System Diseases / Q000473:pathology / Q000503:physiopathology* / Q000652:urine; D005911:Gliosis / Q000473:pathology; D006801:Humans; D008297:Male; D008526:Medulla Oblongata / Q000473:pathology; D008875:Middle Aged; D009847:Olivary Nucleus / Q000473:pathology; D011149:Pons / Q000473:pathology; D012119:Respiration; D012154:Reticular Formation / Q000473:pathology; D012890:Sleep; D013577:Syndrome; D014667:Vasopressins / Q000378:metabolism*; D014851:Wakefulness
chemical_list: D014667:Vasopressins; D002245:Carbon Dioxide