title: [Macrolide antibiotics for oral intake in the treatment and prevention of suppurative surgical infection].
abstract: The authors studied the clinical efficacy of antibiotics of the macrolides group--erythromycin, oleandomycin, triacetylalleandomycin and leukomycin--in complex treatment of 280 patients with suppurative surgical infection caused by a gram-positive, mainly staphylococcal, microbial flora. Various medicinal forms were used: tablets, capsules, granules, syrup. Efficacy of treatment comprised 70-78 per cent. Tolerance of antibiotics was good in the majority of patients.
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002214:Capsules; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D004917:Erythromycin / Q000627:therapeutic use; D006801:Humans; D007933:Leucomycins / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009827:Oleandomycin / Q000627:therapeutic use; D014677:Pharmaceutical Vehicles; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000517:prevention & control; D014586:USSR
chemical_list: D000900:Anti-Bacterial Agents; D002214:Capsules; D007933:Leucomycins; D014677:Pharmaceutical Vehicles; D004917:Erythromycin; D009827:Oleandomycin
vernacular_title: Makrolidnye antibiotiki dlia priema vnutr' pri lechenii i profilaktike gnoĭnoĭ khirurgicheskoĭ infektsii