Drug and psychotherapy interactions in depression.
The authors conducted a series of multiple regression analyses of data from depressed patients. They found that 8 factors consistently predicted treatment response: a lower initial level of distress, imipramine treatment, a positive attitude toward group psychotherapy, and a good employment history predicted lower posttreatment distress levels; estrogen maintenance treatment was related to better response to diazepam, and a low level of intelligence predicted better response to both diazepam and imipramine; and a low initial level of interpersonal sensitivity and a significant other's having an unfavorable attitude toward psychiatric treatment were associated with better response to group psychotherapy.
D001007:Anxiety; D001290:Attitude; D003863:Depression / Q000628:therapy*; D003975:Diazepam / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004651:Employment; D004967:Estrogens / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use*; D007360:Intelligence; D007398:Interpersonal Relations; D011379:Prognosis; D011613:Psychotherapy; D011615:Psychotherapy, Group; D012044:Regression Analysis
D004967:Estrogens; D007099:Imipramine; D003975:Diazepam