Total thyroidectomy and parathyroid autotransplantation for radiation-associated thyroid cancer.
In seventy patients with nodular thyroids and a history of radiation exposure, total thyroidectomy disclosed a 54% incidence of carcinoma; more than half of them had cervial node metastases; four had distant metastases. Fourteen patients required radical neck dissection. The carcinoma was multicentric (both lobes) in 45%. In four patients the carcinoma was found in the lobe contralateral to the one containing the palpable nodule. These findings support the advocates of total thyroidectomy for patients with a nodular thyroid and a history of radiation exposure, provided this operation can be performed with a low incidence of recurrent nerve palsy and hypoparathyroidism.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000473:pathology / Q000601:surgery*; D010280:Parathyroid Glands / Q000502:physiology / Q000637:transplantation*; D011183:Postoperative Complications; D013964:Thyroid Neoplasms / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D013965:Thyroidectomy; D014182:Transplantation, Autologous