title: Chromosomal band assignments of the genes encoding human FKBP12 and FKBP13.
abstract: Human FKBP12 and FKBP13 are encoded by distinct genes designated FKBP1 and FKBP2, respectively. Human FKBP1 was previously characterized. The characterization of human FKBP2 is described. FKBP2 is three kb in length and contains six exons. Fluorescence in situ hybridization of FKBP1 and FKBP2 genomic probes to metaphase chromosomes localized FKBP1 to human chromosome 20 band p13 and FKBP2 to human chromosome 11 band q13.1-q13.3.
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D002352:Carrier Proteins / Q000235:genetics*; D002871:Chromosome Banding; D002880:Chromosomes, Human, Pair 11; D002890:Chromosomes, Human, Pair 20; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D015342:DNA Probes; D006801:Humans; D008969:Molecular Sequence Data; D015183:Restriction Mapping; D016559:Tacrolimus / Q000378:metabolism; D022021:Tacrolimus Binding Proteins
chemical_list: D002352:Carrier Proteins; D015342:DNA Probes; D004247:DNA; D022021:Tacrolimus Binding Proteins; D016559:Tacrolimus