Modulatory actions of ovine luteinizing hormone-releasing hormone and Mystus gonadotropin on gamma-BHC-induced changes in lipid levels in the freshwater catfish, Heteropneustes fossilis.
Female specimens of Heteropneustes fossilis were exposed to a sublethal concentration of gamma-BHC (16 mg/liter) for 4 weeks during the preparatory and prespawning phases of their annual reproductive cycle. The effect of gamma-BHC on free fatty acids (FFA), monoglycerides (MG), diglycerides (DG), and triglycerides (TG) was monitored. gamma-BHC in general was inhibitory to lipogenesis during both of the reproductively active phases as judged by decreased levels of FFA, MG, DG, and TG. Lower doses of ovine luteinizing hormone-releasing hormone (oLH-RH) and Mystus gonadotropin (mGTH) were ineffective in modulating the impact of gamma-BHC; however, their higher doses effectively revoked the impact of gamma-BHC. From the evidence obtained here, it is concluded that gamma-BHC suppressed the action of oLH-RH and mGTH and affected lipogenesis in this species.
D000818:Animals; D002397:Catfishes; D005230:Fatty Acids, Nonesterified / Q000032:analysis* / Q000097:blood; D005260:Female; D005989:Glycerides / Q000032:analysis* / Q000097:blood; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D006062:Gonadotropins / Q000494:pharmacology*; D001556:Hexachlorocyclohexane / Q000009:adverse effects*; D008099:Liver / Q000737:chemistry*; D010053:Ovary / Q000737:chemistry*; D012098:Reproduction / Q000187:drug effects*
D005230:Fatty Acids, Nonesterified; D005989:Glycerides; D006062:Gonadotropins; D007987:Gonadotropin-Releasing Hormone; D001556:Hexachlorocyclohexane