Identification of a methylated catechol metabolite of glutethimide (Doriden) in human urine.
A new metabolite of glutethimide has been isolated and identified as a methylated catechol. Gas chromatographic parameters as well as mass spectral data are presented which clearly reveal this metabolite to be present in enzymatically hydrolyzed urine of patients severely intoxicated by the parent drug.
D002396:Catechols / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D005984:Glutethimide / Q000031:analogs & derivatives / Q000652:urine*; D006801:Humans
D002396:Catechols; D005984:Glutethimide