[The villous trophoblast in placentae of premature births (author's transl)].
Enzyme histochemical behavier (cryostat-and semi-thin slice techniques) of the villous epithelium of 109 "genuine" premature birth permits evaluation of a qualitative disturbance of trophoblasts. It is characterised by an increase of pre-degenerative plasmodium and multilocular emergence of highly differentiated or degenerated Langhans cells which lack the potential for plasmodial transformation and thus for regeneration of trophoblasts. The importance of such changes for metabolic competence and hormone synthesis and the link between prematurity and insuficiency of the placenta are discussed.
D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D002824:Chorionic Villi / Q000201:enzymology*; D004847:Epithelial Cells; D004848:Epithelium / Q000201:enzymology; D005260:Female; D005634:Fructose-Bisphosphate Aldolase / Q000378:metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D005969:Glutamate Dehydrogenase / Q000378:metabolism; D006651:Histocytochemistry; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007521:Isocitrate Dehydrogenase / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008995:Monoamine Oxidase / Q000378:metabolism; D007752:Obstetric Labor, Premature / Q000201:enzymology; D010920:Placenta / Q000201:enzymology*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D013385:Succinate Dehydrogenase / Q000378:metabolism; D014327:Trophoblasts / Q000166:cytology / Q000201:enzymology*
D007770:L-Lactate Dehydrogenase; D007521:Isocitrate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D013385:Succinate Dehydrogenase; D005969:Glutamate Dehydrogenase; D008995:Monoamine Oxidase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D005634:Fructose-Bisphosphate Aldolase
Der Zottentrophoblast in den Plazenten Frühgeborener (Eine enzymhistochemische Studie)