Bile-induced acute erosive gastritis. Its prevention by antacid, cholestyramine, and prostaglandin E2.
Intragastric administration of whole bile-produced acute erosive gastritis in rats. Concomitant intragastric administration of prostaglandin E2, Cholestyramine and an antacid (Maalox) was effective in preventing this type of acute erosive gastritis. The protective rffect of prostaglandin E - 2 in this regard was significantly more marked as compared to Cholestyramine and Maalox.
D000208:Acute Disease; D000818:Animals; D000863:Antacids / Q000627:therapeutic use*; D001646:Bile; D002792:Cholestyramine Resin / Q000627:therapeutic use*; D005756:Gastritis / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control; D008297:Male; D011458:Prostaglandins E / Q000627:therapeutic use*; D051381:Rats
D000863:Antacids; D011458:Prostaglandins E; D002792:Cholestyramine Resin