title: Single oral dose of 1-5g. talampicillin in the treatment of gonorrhoea.
abstract: 81 patients have been treated with single oral doses of 1-5 g. (6 tablets) of talampicillin without probenecid. The failure rate amongst those followed was only 4-2 per cent. No side-effects were reported. These results were superior to those obtained with 2-0g. or equivalent of ampicillin, amoxycillin, or pivampicillin with probenecid. Talampicillin is thus the most potent ampicillin-like antibiotic so far available for the treatment of gonorrhoea and is capable of curing the disease with a smaller single dose without probenecid than is necessary for other preparations.
mesh_terms: D000284:Administration, Oral; D000658:Amoxicillin / Q000627:therapeutic use; D000667:Ampicillin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005500:Follow-Up Studies; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008297:Male; D010917:Pivampicillin / Q000627:therapeutic use
chemical_list: D010917:Pivampicillin; D000667:Ampicillin; D000658:Amoxicillin