Studies on erythrocyte metabolism following acute blood loss in the horse.
Anaemic horses do not provide reticulocytes during an erythropietic response. Acute blood loss was studied in 4 ponies as a model to monitor changes in erythrocyte metabolism during active erythropoiesis. Following phlebotomy, erythrocyte adenosine-5-triphosphate, adenosine-5-diphosphate, glucose-6-phosphate, fructose-6-phosphate, and phosphoenolpyruvate increased signifcantly. The remaining glycolytic intermediates did not change. It is suggested that the determination of erythrocyte adenosine-5-triphosphate may be used to evaluate erythrocyte response following acute blood loss in the horse.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000743:Anemia, Hemolytic / Q000097:blood / Q000662:veterinary*; D000818:Animals; D001815:Bloodletting; D004920:Erythropoiesis; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006734:Horse Diseases / Q000097:blood*; D006736:Horses
D006454:Hemoglobins; D000255:Adenosine Triphosphate