title: [The dangers of antibiotic therapy in gram-negative pathogens (author's transl)].
abstract: The increased occurrence of so-called gram-negative problem bacteria in urology compels us to use highly effective antibiotics in optimal doses. The danger of such therapy is illustrated by three cases in whom toxic damage was demonstrated following combined treatment with aminoglycosides and cephalosporins.
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced; D000328:Adult; D001002:Anuria / Q000139:chemically induced; D001424:Bacterial Infections / Q000139:chemically induced; D003638:Deafness / Q000139:chemically induced; D004359:Drug Therapy, Combination; D005260:Female; D005839:Gentamicins / Q000009:adverse effects* / Q000627:therapeutic use / Q000633:toxicity; D006088:Gram-Negative Aerobic Bacteria; D006089:Gram-Negative Anaerobic Bacteria; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced*; D007683:Kidney Tubular Necrosis, Acute / Q000139:chemically induced; D008875:Middle Aged; D011014:Pneumonia / Q000188:drug therapy; D018805:Sepsis / Q000188:drug therapy
chemical_list: D005839:Gentamicins
vernacular_title: Die gefahren der Antibiotikatherapie bei gramnegativen Erregern