title: [Local use of neomycin. The histomorphological changes on the part of the neuroreceptor apparatus of the rabbit cornea].
abstract: The experimental histological studies with rabbits showed that neomycin in the form of 1 and 10 per cent solutions and ointments used for prolong periods of time affected the neuroreceptor apparatus of the animal cornea. It is not recommended to use 10 per cent solutions and ointments in the ophthalmological practice. Before using neomycin it is necessary to examine the cornea sensitivity and if it is lowered, the antibiotic should not be used.
mesh_terms: D000287:Administration, Topical; D000818:Animals; D003315:Cornea / Q000187:drug effects* / Q000473:pathology; D004305:Dose-Response Relationship, Drug; D009355:Neomycin / Q000008:administration & dosage / Q000494:pharmacology*; D011817:Rabbits; D011984:Sensory Receptor Cells / Q000187:drug effects* / Q000473:pathology; D012996:Solutions; D013997:Time Factors
chemical_list: D012996:Solutions; D009355:Neomycin
vernacular_title: Mestnoe primenenie neomitsina. Gistomorfologicheskie izmeneniia so storony nervnoretseptornogo apparata rogovitsy glaza krolika