[Adenylate cyclase activity in human nasal polyps under conditions of stimulation of serotonin biosynthesis (in vitro)].
Nasal polyp tissue possess adenylatecyclase activity. Under conditions of incubation of nasal polyps with the use of reserpine (an activator of serotonin synthesis in this tissue) there can be observed a statistically significant increase of adenylatecyclase activity. During the first minutes of the polyp incubation with reserpine the activity of the enzyme rose ten-fold. Participation of the adenylatecyclase system at the initial stages of morphological and biochemical differentiation, accompanying serotonin biosynthesis in human nose polyps was confirmed.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D002455:Cell Division; D004804:Eosinophils; D006801:Humans; D066298:In Vitro Techniques; D009298:Nasal Polyps / Q000201:enzymology* / Q000378:metabolism / Q000473:pathology; D012110:Reserpine / Q000494:pharmacology*; D012701:Serotonin / Q000096:biosynthesis*; D013268:Stimulation, Chemical
D012701:Serotonin; D012110:Reserpine; D000262:Adenylyl Cyclases
Adenilattsiklaznaia aktivnost' polipov nosa cheloveka v usloviiakh stimuliatsii biosinteza serotonina (in vitro)