title: Enzymes in intestinal mucosa from patients with rheumatoid diseases.
abstract: Jejunal mucosa from arthritic and control subjects was obtained by intraluminal biopsy or at operation and analysed for eight different enzymes. Histidinemethyl-esterase showed 6 to 10 times higher values in patients uith rheumatoid arthritis on comparison with control individuals in respective series. A disturbance in the histidine metabolism in these patients, possible depending on their intestinal flora, is discussed.
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism; D000626:Aminopeptidases / Q000378:metabolism; D001168:Arthritis / Q000201:enzymology*; D001172:Arthritis, Rheumatoid / Q000201:enzymology; D004765:Enteropeptidase / Q000378:metabolism; D004950:Esterases / Q000378:metabolism; D006801:Humans; D007413:Intestinal Mucosa / Q000201:enzymology*; D007583:Jejunum / Q000201:enzymology*; D007931:Leucyl Aminopeptidase / Q000378:metabolism; D008180:Lupus Erythematosus, Systemic / Q000201:enzymology; D012595:Scleroderma, Systemic / Q000201:enzymology
chemical_list: D004950:Esterases; D000469:Alkaline Phosphatase; D000626:Aminopeptidases; D007931:Leucyl Aminopeptidase; D004765:Enteropeptidase