[Collagen peptidase in Crohn's disease].
Collagen-peptidase activity in serum was increased in 54 of 71 cases of Crohn's disease. This increase was highly significant (P less than 0.001) compared with the results in a control group (24 cases). Immunosuppressive drugs (corticosteroids, azathioprine) decreased collagen-peptidase activity in the patients with Crohn's disease. On average it was higher than that of patients with sarcoidosis. Further tests are required to establish whether collagen-peptidase activity is of diagnostic value in Crohn's disease.
D000305:Adrenal Cortex Hormones / Q000494:pharmacology; D001379:Azathioprine / Q000494:pharmacology; D003094:Collagen; D003424:Crohn Disease / Q000201:enzymology*; D006801:Humans; D010447:Peptide Hydrolases / Q000097:blood*; D012507:Sarcoidosis / Q000201:enzymology
D000305:Adrenal Cortex Hormones; D003094:Collagen; D010447:Peptide Hydrolases; D001379:Azathioprine
Kollagenpeptidase bei Morbus Crohn