[Sex hormone reception in the human endometrium in normal and pathological pregnancy].
A study was made of reception of 17 beta-estradiol, progesterone, and testosterone in human endometrium during pregnancy. In the cytozol of the endometrium each of the sex steroids was bound by three different receptor components, two of which were represented by highly specific proteins. The maximal capacity of specific cytozol receptors to each of the sex steroids was measured in normal and pathological pregnancy; in the latter case the number of receptors to progesterone proved to be decreased. It is supposed that one of the specific binding components is necessary only under conditions of increased functional load upon the organ.
D003600:Cytosol / Q000502:physiology; D004717:Endometrium / Q000502:physiology*; D004958:Estradiol / Q000502:physiology; D005260:Female; D012739:Gonadal Steroid Hormones / Q000502:physiology*; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011261:Pregnancy Trimester, First; D011374:Progesterone / Q000502:physiology; D011485:Protein Binding; D011955:Receptors, Drug; D013739:Testosterone / Q000502:physiology; D014316:Tritium
D012739:Gonadal Steroid Hormones; D011955:Receptors, Drug; D014316:Tritium; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol
Retseptsiia polovykh gormonov v éndometrii cheloveka pri normal'noĭ i patologicheskoĭ beremennosti