Recurrent arterial thrombosis in nephrosis.
Recurrent arterial thrombosis without inciting trauma occurred in an 8-year-old boy with the nephrotic syndrome. Thrombosis of the left femoral artery was successfully managed by early thrombectomy and postoperative anticoagulation therapy, but the right leg finally had to be amputated. The development of hypovolemia in the nephrotic child receiving long-term steroid therapy apparently increases the tendency to a hypercoagulable state.
D000305:Adrenal Cortex Hormones / Q000009:adverse effects* / Q000627:therapeutic use; D000671:Amputation, Surgical; D001779:Blood Coagulation Factors; D002675:Child, Preschool; D005263:Femoral Artery; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000097:blood / Q000188:drug therapy*; D013927:Thrombosis / Q000209:etiology* / Q000601:surgery
D000305:Adrenal Cortex Hormones; D001779:Blood Coagulation Factors