The measurement of diphenoxylic acid in plasma following administration of diphenoxylate.
The measurement of diphenoxylic acid, the major metabolite of diphenoxylate, has been performed in man using a deuterium labelled internal standard and multiple ion monitoring using a gas chromatograph mass spectrometer. The determination of plasma concentrations following administration of diphenoxylate to man is described.
D002849:Chromatography, Gas; D004157:Diphenoxylate / Q000097:blood* / Q000378:metabolism / Q000592:standards; D006801:Humans; D007540:Isonipecotic Acids / Q000097:blood*; D013058:Mass Spectrometry
D007540:Isonipecotic Acids; D004157:Diphenoxylate