Tumor inhibitors II: constituents and antitumor activity of Sarracenia flava.
The chloroform extracts of the roots and leaves of Sarracenia flava showed antitumor activity against lymphocytic leukemia P-388. Lupeol was identified as one constituent responsible for this activity. Beta-Sitosterol and alpha-amyrin were isolated from the hexane extract of the roots.
D000438:Alcohols / Q000032:analysis; D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005231:Fatty Acids, Unsaturated / Q000032:analysis; D007942:Leukemia, Experimental / Q000188:drug therapy*; D051379:Mice; D008815:Mice, Inbred Strains; D053978:Pentacyclic Triterpenes; D010936:Plant Extracts / Q000032:analysis / Q000627:therapeutic use*; D010946:Plants, Medicinal; D012855:Sitosterols / Q000032:analysis; D014315:Triterpenes / Q000032:analysis; D000094042:Lupanes
D000438:Alcohols; D000970:Antineoplastic Agents; D005231:Fatty Acids, Unsaturated; D053978:Pentacyclic Triterpenes; D010936:Plant Extracts; D012855:Sitosterols; D014315:Triterpenes; C010480:lupeol; D000094042:Lupanes