title: Modification to single catheter exchange transfusion technique.
abstract: A simple modification to the standard 'in-out' exchange transfusion technique is described which requires cannulation of the umbilical vein only, yet provides many of the theoretical and practical advantages of a 2-catheter arteriovenous technique. The advantages include a reduction of cardiovascular disturbance; a reduction of the inevitable pressure changes in the portal venous system (probably important in the pathogenesis of complicating necrotizing enterocolitis); administration of alkali or drugs diluted in donor blood; accurate assessment of balance; a more efficient exchange; and general ease of management allowing better clinical observation of the infant.
mesh_terms: D000142:Acidosis, Respiratory / Q000188:drug therapy; D001639:Bicarbonates / Q000627:therapeutic use; D002320:Cardiovascular Physiological Phenomena; D002404:Catheterization / Q000379:methods*; D004761:Enterocolitis, Pseudomembranous / Q000209:etiology; D005078:Exchange Transfusion, Whole Blood / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D007231:Infant, Newborn; D012964:Sodium / Q000627:therapeutic use; D014471:Umbilical Veins / Q000601:surgery
chemical_list: D001639:Bicarbonates; D012964:Sodium