title: [DNA metabolism in the immunocompetent organs of C57BL mice in chemical carcinogenesis].
abstract: DNA synthesis was determined in small lymphocytes nuclei in mice C57BL during the process of methylcholanthrene induced carcinogenesis. Both in the pretumor period and in animals with a tumor the DNA synthesis in lymph node lymphocytes nuclei was found to be decreased. Inhibition of the DNA synthesis is greatly pronounced in lymphocytes adjacent to the site of lymph node tumor development.
mesh_terms: D000818:Animals; D004247:DNA / Q000096:biosynthesis*; D008198:Lymph Nodes / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D008748:Methylcholanthrene; D051379:Mice; D008810:Mice, Inbred C57BL; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000276:immunology*
chemical_list: D008748:Methylcholanthrene; D004247:DNA
vernacular_title: Obmen DNK v immunokompetentnykh organakh mysheĭ C57BL pri khimicheskom kantserogeneze