[Changes in the thyrocytes to the administration of intermedin under conditions of the aminazine-altered functional state of the nervous system].
Histological and electron microscopial investigations of the thyroid gland were performed in white mice after exogeneous administration of intermedin (MSH) and intermedin against the background of aminasin. It may be concluded that while a prolonged injection of MSH results in the stimulation of the thyroid gland, the administration of the hormone in question against the background of aminasin results in the same ultramorphological structural changes of the gland which are observed after injection of aminasin alone, causing a decreased functional activity of the thyroid gland. The effect of intermedin upon the thyroid is supposed to be realized through those hypothalamus structures which are responsible for the regulation of the thyrotropic function of the hypophysis.
D000818:Animals; D002746:Chlorpromazine / Q000494:pharmacology*; D004847:Epithelial Cells; D004848:Epithelium / Q000187:drug effects / Q000648:ultrastructure; D007031:Hypothalamus / Q000187:drug effects; D008297:Male; D009074:Melanocyte-Stimulating Hormones / Q000494:pharmacology*; D009420:Nervous System / Q000187:drug effects*; D009490:Neurosecretory Systems / Q000187:drug effects / Q000648:ultrastructure; D051381:Rats; D013961:Thyroid Gland / Q000187:drug effects* / Q000502:physiology / Q000648:ultrastructure; D013997:Time Factors
D009074:Melanocyte-Stimulating Hormones; D002746:Chlorpromazine
Izmeneniia tireotsitov pri vvedenii intermedina v usloviiakh izmenennogo aminazinom funktsional'nogo sostoianiia nervoĭ sistemy