title: [The role of renal beta-adrenoreceptors in regulating its blood supply and urine formation].
abstract: The dog kidney blood flow and filtrative and reabsorptive functions were studied with the aid of electromagnetic flowmeter and endogenic creatinine. Beta-adrenostimulation with izadrine caused dilatation of the kidney vessels. Beta-adrenoblockade led to the opposite though insignificant effect. Beta-adrenostimulation in intact animals entailed systemic hypotension, activation of the kidney blood flow and reabsorption, decrease of filtration and diuresis. Following stabilization of arterial pressure or central inhibition of vasopressin, the beta-adrenostimulation led to the decrease in reabsorption. The data obtained seem to indicate that the direct effect of beta-adrenostimulation of the kidney channels is manifested by the inhibition of reabsorption.
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D001808:Blood Vessels / Q000294:innervation; D004231:Diuresis / Q000187:drug effects; D004285:Dogs; D005919:Glomerular Filtration Rate / Q000187:drug effects; D007545:Isoproterenol / Q000494:pharmacology; D007668:Kidney / Q000098:blood supply / Q000294:innervation*; D007684:Kidney Tubules / Q000294:innervation; D011433:Propranolol / Q000494:pharmacology; D011941:Receptors, Adrenergic; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D011941:Receptors, Adrenergic; D011433:Propranolol; D007545:Isoproterenol
vernacular_title: O znachenii beta-adrenoretseptorov pochki v reguliatsii ee krovosnabzheniia i mocheobrazovatel'noĭ funktsii