Plasmapheresis-induced hemodilution and its effects on serum constituents.
Samples were obtained from 23 plasmapheresis donors before, during, and after double plasmapheresis. Seventeen chemical analyses were performed on these specimens and the results were subjected to statistical analysis. Representative samples can be obtained from plasmapheresis donors before the procedure has begun, immediately after the first unit of whole blood has been removed, or 15 minutes after the completion of the entire procedure. The sample obtained after the first unit of whole blood has been removed will show dilutional lowering of the uric acid concentration and the 15-minute equilibration sample will show dilutional lowering of the inorganic phosphorus concentration. Short-term donors and long-term donors manifest a somewhat different hemodilutional response to plasmapheresis.
D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood; D001774:Blood Chemical Analysis; D001798:Blood Proteins / Q000032:analysis; D001806:Blood Urea Nitrogen; D001810:Blood Volume; D002118:Calcium / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D010758:Phosphorus / Q000097:blood; D010956:Plasmapheresis; D012709:Serum Albumin / Q000032:analysis; D013997:Time Factors; D014527:Uric Acid / Q000097:blood
D001798:Blood Proteins; D012709:Serum Albumin; D014527:Uric Acid; D010758:Phosphorus; D000469:Alkaline Phosphatase; D002118:Calcium