title: Symptomatic choroidal metastases in breast cancer.
abstract: A series of 21 consecutive patients with carcinoma of the breast and symptomatic choroidal metastases was reviewed. All patients were symptomatic of choroidal metastases at presentation. Most patients had disease progression at other sites at the time of diagnosis. The incidence of cerebral metastases was not increased in this group compared to that in patients with metastatic breast cancer at other sites. Radiotherapy using a direct anterior field proved effective palliation for this disease site. Of the 32 eyes treated, serial visual acuity was documented in 23. Seventeen showed objective improvement and six showed stabilisation. The median duration of improvement was 11.5 months.
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology*; D002277:Carcinoma / Q000175:diagnosis / Q000532:radiotherapy / Q000556:secondary*; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000556:secondary*; D005260:Female; D006801:Humans; D010166:Palliative Care; D014792:Visual Acuity