Melatonin-induced inhibition of testicular function in adult golden hamsters.
Melatonin (12-100 mug/day) administered via subcutaneous Silastic implants prevented or suppressed light-induced testicular recrudescence in adult golden hamsters. In addition, melatonin (150 mug/day) induced marked testicular regression in sexually mature hamsters maintained on photostimulatory long days. These results clearly establish that exogenous melatonin can inhibit gonodal function in adult male hamsters.
D000818:Animals; D006224:Cricetinae; D004343:Drug Implants; D008297:Male; D009929:Organ Size / Q000187:drug effects; D013087:Spermatids / Q000187:drug effects; D013090:Spermatocytes / Q000187:drug effects; D013093:Spermatogonia / Q000187:drug effects; D013737:Testis / Q000033:anatomy & histology / Q000166:cytology / Q000187:drug effects*
D004343:Drug Implants