Renovascular hypertension: does the renal vein renin ratio predict operative results?
Renal vein renin ratios from 56 hypertensive patients who were operated upon for unilateral stenosis of a main renal artery were compared to blood pressure response to a corrective operation. In patients with renal vein renin ratios greater then 2.0, the upper limits of normal for essential hypertension (95 per cent confidence limits), the cure/improvement rate approximated 90 per cent. However, in patients operated upon despite lesser ratios the cure/improvement rate was also high--83 per cent in our series and 57 per cent in collected reports from the literature. Thus, the test may be falsely negative in a high percentage of patients. Renal vein renin ratios would appear to be most useful in confirming but not necessarily in denying the functional significance of a renal artery stenosis.
D000328:Adult; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology / Q000601:surgery*; D008297:Male; D012078:Renal Artery Obstruction / Q000150:complications / Q000601:surgery*; D012082:Renal Veins; D012083:Renin / Q000097:blood* / Q000502:physiology; D012189:Retrospective Studies
D012083:Renin