[Myasthenia, thymoma and hypophyseal tumor associated with heterogenous adenomatous proliferation and ganglioneuroma of the sella turcica].
The authors report a case of myasthenia gravis in which a tumour of the sella turcica, without clinical symptoms, was discovered on X-ray examination of the skull and was removed with success. Histological study showed endocrine and neural type cells with cells of intermediate type. Subsequent thoracic surgery was performed with removal of a thymoma which was not visible on X-ray examination of the chest. The first operation on the sella turcica had no effect on the myasthenia but after the second on the thymoma a definite improvement was noted. The association of myasthenia, thymoma and ganglioneuroma of the sella turcica is unknown. In order to explain this, the authors hypothesize a common origin in the neural crests of both tumours.
D000236:Adenoma / Q000150:complications*; D000328:Adult; D005729:Ganglioneuroma / Q000150:complications*; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000150:complications* / Q000628:therapy; D010911:Pituitary Neoplasms / Q000150:complications*; D012658:Sella Turcica; D012888:Skull Neoplasms / Q000150:complications*; D013945:Thymoma / Q000150:complications / Q000601:surgery; D013953:Thymus Neoplasms / Q000150:complications / Q000601:surgery
Myasthénie, thymome et tumeur hypophysaire associant une prolifération adénomateuse hétérogène et un ganglio-neurome de la selle turcique