Serum immunoglobulin levels in cancer patients. II. Serum immunoglobulins and stage of tumor progress.
A study of the IgG, IgA and IgM levels in relation with the clinical course of the tumor disorders revealed the IgG values to correlate with the progress of the disease. Their levels were found to rise from stage I to stage III of the classification according to tumor progress, the difference between these stages being of statistical significance. A similar trend, though statistically nonsignificant, was noted also in IgA levels, but these proved right from the start to be higher than the values reported for the apparent normal population. The rising tendency in the IgG--and the less striking one in the IgA levels were also confirmed by a comparison of the mean values of collections separated by a definite time interval in the same patients and this both for the deteriorated and unchanged cases, but not for the group of improved patients.
D000912:Antibodies, Neoplasm / Q000032:analysis; D000917:Antibody Formation; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000097:blood / Q000276:immunology*; D011379:Prognosis
D000912:Antibodies, Neoplasm; D007136:Immunoglobulins