Sodium pump: its importance to intercellular communication in heart fibres.
The effect of ouabain on the electrical coupling of canine Purkinje cells was investigated. It was found that the glycoside decreases cell communication through an increase in junctional resistance, what supports the view that the sodium pump has an important role on the control of cell communication.
D000818:Animals; D001693:Biological Transport, Active; D004285:Dogs; D004553:Electric Conductivity; D010042:Ouabain / Q000494:pharmacology*; D011690:Purkinje Fibers / Q000187:drug effects / Q000502:physiology*; D012964:Sodium / Q000378:metabolism / Q000494:pharmacology
D010042:Ouabain; D012964:Sodium