title: [Antigen therapy in chronic brucellosis].
abstract: The different forms of chronic brucellosis have been improved and well stabilized in the proportion of 75% by repeated injections of a vaccine consisting of suspensions of heat-killed B. melitensis. The vaccine should be used in a series of 8 subcutaneous injections, in increasing doses, at the rate of 2 injections a week. To obtain good results it is necessary to give an average of 3 to 4 series of injections, with a two months' interval between each series. After the 2nd series a distinct decrease of the patient's reactions to retarded hypersensitivity tests are generally observed. The most favourable results are obtained in cases of common subjective syndrome with physical and psychical asthenia.
mesh_terms: D000942:Antigens, Bacterial / Q000008:administration & dosage; D002002:Brucella / Q000276:immunology; D002004:Brucella Vaccine / Q000627:therapeutic use*; D002006:Brucellosis / Q000276:immunology / Q000628:therapy*; D002908:Chronic Disease; D007167:Immunotherapy
chemical_list: D000942:Antigens, Bacterial; D002004:Brucella Vaccine
vernacular_title: L'antigénothérapie dans la brucellose chronique