Precocious puberty in rats induced by hypothalamic lesions: a comparison of platinum and stainless steel electrodes.
Precocious sexual maturation was induced in immature female rats by 2 types of unilateral hypothalamic lesions. Stainless steel electrodes produced smaller tissue defects but proved more efficient than platinum electrodes.
D000818:Animals; D004566:Electrodes; D004967:Estrogens / Q000378:metabolism; D005260:Female; D007031:Hypothalamus / Q000502:physiology*; D009929:Organ Size; D010053:Ovary / Q000502:physiology*; D010984:Platinum; D011374:Progesterone / Q000378:metabolism; D011629:Puberty, Precocious / Q000209:etiology*; D051381:Rats; D013193:Stainless Steel
D004967:Estrogens; D013193:Stainless Steel; D010984:Platinum; D011374:Progesterone