Hypercholesterolemia due to ascorbic acid.
Rats fed a purified diet containing ascorbic acid developed hypercholesterolemia. Because rats do not require exogenous ascorbic acid, they may be comparable to humans who supplement their diets with ascorbic acid in capsular form. The amount of ascorbic acid in this experiment was equivalent to 82 to 630 mg of capsular ascorbic acid ingested by an average man and was well below the amount ingested by those in search of respiratory benefit. The data are consonant with those on humans consuming controlled diets.
D000818:Animals; D001205:Ascorbic Acid; D006937:Hypercholesterolemia / Q000139:chemically induced*; D008297:Male
D001205:Ascorbic Acid