title: Some consequences of the ingestion by young and growing pigs of feed contaminated with ergot.
abstract: Growing pigs were fed freshly milled ergot sclerotia (Claviceps purpurea Fr (Tul)) from North American wheat containing 0-31 per cent of total alkaloids of which 30 per cent was ergotoxine, 30 per cent ergosine, 20 per cent ergotamine and 20 per cent other ergot alkaloids. Pigs were induced to ingest a diet heavily contaminated with ergot (10 per cent w/w). The presence of ergot reduced feed intake and growth of the pigs, but there was no evidence of peripheral necrosis, of internal or external haemorrhage, or of changes in haemotological characteristics. Balance experiments in which the diet was contaminated with 4 per cent (w/w) of ergot showed that 90 per cent of the alkaloids were absorbed by the pigs, but none could be detected in tissues or urine. The ingestion of ergot did not affect the digestibility of the diet, but the urinary excretion of nitrogen was increased and the retention of nitrogen reduced. The presence of ricinoleic acid was shown to be a useful diagnostic feature of ergot contamination of diets, digesta and faeces; it was not found in body tissues.
mesh_terms: D000821:Animal Feed; D000818:Animals; D001835:Body Weight; D002967:Claviceps; D004876:Ergot Alkaloids / Q000378:metabolism; D005227:Fatty Acids / Q000378:metabolism; D008297:Male; D009584:Nitrogen / Q000652:urine; D012277:Ricinoleic Acids / Q000378:metabolism; D013552:Swine / Q000254:growth & development / Q000378:metabolism*
chemical_list: D004876:Ergot Alkaloids; D005227:Fatty Acids; D012277:Ricinoleic Acids; D009584:Nitrogen