title: [Preconvulsive state and hyperfunction of the striatum (clinico-experimental findings)].
abstract: The paper is concerned with a clinico-experimental study of the influence of intesified activity in the neostriatum on the EEG indices which may appear during the introduction of increased doses of corazol. In 10 cases with different forms of parkinsonism there was a much  easier appearance of clinical and EEG manifestations of convulsive activity, than in normals. In experiments on rats preconvulsive effects were exerted by such neuroleptics as haloperidol unlike apomorphine, possessing opposite properties.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001058:Apomorphine; D003292:Convulsants; D003342:Corpus Striatum / Q000503:physiopathology*; D004569:Electroencephalography; D006220:Haloperidol; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology*; D010301:Parkinson Disease, Postencephalitic / Q000503:physiopathology; D010302:Parkinson Disease, Secondary / Q000503:physiopathology; D010433:Pentylenetetrazole; D051381:Rats; D012640:Seizures / Q000139:chemically induced / Q000188:drug therapy
chemical_list: D003292:Convulsants; D006220:Haloperidol; D001058:Apomorphine; D010433:Pentylenetetrazole
vernacular_title: Predsudorozhnoe sostoianie i giperfunktsiia striatuma (kliniko-éksperimental'nye dannye)