title: Subcutaneous mastectomy and fibrocystic disease of the breast.
abstract: There has been a considerable amount of data presented to implicate moderate to severe fibrocystic disease as a strong precursor of breast cancer. When a premenopausal woman with nodular breasts presents a biopsy examination characterized by sclerosing adenosis, intraductal hyperplasia and/or papillomatosis, microcystic disease, macrocystic disease, or lobular neoplasia, her malignant potential will be much greater than when these disease processes are absent. As a result, a prophylactic subcutaneous mastectomy is indicated and breast reconstruction with either an immediate or a delayed mammary prosthesis implantation should be performed.
mesh_terms: D000328:Adult; D001941:Breast Diseases / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D001943:Breast Neoplasms / Q000150:complications / Q000453:epidemiology / Q000473:pathology; D002140:California; D002278:Carcinoma in Situ / Q000473:pathology; D003560:Cysts / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008408:Mastectomy / Q000379:methods; D008875:Middle Aged; D011183:Postoperative Complications