Genetic independence between the HL--A system and deficits in the first and sixth components of complement.
From two families, one with Clr deficiency and the other with C6 deficiency, evidence was obtained suggesting genetic independence between the transmission of a 50% deficit in the functional activity of these two complement components and the inheritance of the HL--A system, the ABO system, and the sex of individuals.
D000017:ABO Blood-Group System; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003172:Complement C1 / Q000172:deficiency*; D003183:Complement C6 / Q000172:deficiency*; D003165:Complement System Proteins / Q000172:deficiency*; D005260:Female; D005838:Genotype; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D006650:Histocompatibility Testing; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012737:Sex Factors
D000017:ABO Blood-Group System; D003172:Complement C1; D003183:Complement C6; D006680:HLA Antigens; D006649:Histocompatibility Antigens; D003165:Complement System Proteins