Effects of uterus and prostaglandin F2alpha on corpora lutea in Mongolian gerbils and guinea pigs.
One   or both uterine horns were removed on postpartum day 6 day 1=parturition in pseudopregnant gerbils. On dy 16, the corpora lutea (C) in unilaterally hysterectomized gerbils were smaller (P less than 0.05) in the ovary adjacent to an intact horn than in the ovary adjacent to a removed horn. The cL were smaller in uterine-intact than in completely hysterectomized gerbils. I n another experiment, the cl were smaller (P less than 0.05) in pseudopregnant gerbils given a single intrauterine injection of a 30- or 20-mug dose of prostaglandin F2alpha) (PGFalpha) on postpartum day 6 and theen necropsied on day 10 than in gerbils given 10-, 5-, 1-, and 0-mug doses; CL were smaller (P less than 0.05) on the side ipsilateral to the treated horn than on the opposite side, although the interaction of dose and side was not significant...
D000818:Animals; D003338:Corpus Luteum / Q000033:anatomy & histology / Q000187:drug effects*; D005260:Female; D005849:Gerbillinae / Q000502:physiology*; D006168:Guinea Pigs / Q000502:physiology*; D007044:Hysterectomy; D007267:Injections; D007273:Injections, Intramuscular; D003341:Luteolysis / Q000187:drug effects; D049590:Postpartum Period; D011247:Pregnancy; D011460:Prostaglandins F / Q000008:administration & dosage / Q000494:pharmacology*; D011555:Pseudopregnancy; D014599:Uterus / Q000502:physiology*
D011460:Prostaglandins F