[Interaction of steroid hormones with glutamate dehydrogenase].
The inhibitory action of sex hormones on the glutamate dehydrogenase activity is due to their binding to the enzyme protein. No binding of sex hormones to glutamate dehydrogenase is observed in the presence of L-amino acids, preventing the enzyme dissociation. Under those conditions the enzyme sensitivity to the inhibitory action of the hormones sharply decreases.
D003900:Desoxycorticosterone; D005969:Glutamate Dehydrogenase / Q000037:antagonists & inhibitors; D012739:Gonadal Steroid Hormones; D006854:Hydrocortisone; D007930:Leucine
D012739:Gonadal Steroid Hormones; D003900:Desoxycorticosterone; D005969:Glutamate Dehydrogenase; D007930:Leucine; D006854:Hydrocortisone
Vzaimodeĭstvie steroidnykh gormonov s glutamatdegidrogenazoĭ