[Effects of histones on phagocytosis and phagocytic metabolism].
Enhanced phagocytosis and no intracellular glycogen breakdown was found in guinea-pig peritoneal polymorphonuclear leukocytes (PMN) incubated together with heat-killed staphylococci (Twort) treated with a calf thymus histone fraction (P II), for 1 hr at 37 degrees C. Glcose consumption and lactate production of these PMN's were as high as in phagocytosis of the same germ untreated with P II, and their oxygen consumption was depressed significantly.
D000818:Animals; D005947:Glucose / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism; D006168:Guinea Pigs; D006657:Histones / Q000494:pharmacology*; D007773:Lactates / Q000378:metabolism; D007962:Leukocytes / Q000502:physiology*; D010101:Oxygen Consumption; D010587:Phagocytosis / Q000187:drug effects; D013210:Staphylococcus
D006657:Histones; D007773:Lactates; D006003:Glycogen; D005947:Glucose
Effets des histones sur la phagocytose et le métabolisme phagocytaire