[Distribution of carbon dioxide and oxygen tension in neurons of the cerebral cortex and their surrounding tissue].
Mathematical model of the capillary network with a neuron body in the center makes it possible to calculate CO2 and O2 pressures at different points of the neuron and the tissue. On this model the influence of arterial pCO2 on the O2 transport from the capillaries to neuron and surrounding tissue was studied. The pCO2 in the brain tissue, in contrast to pO2, was found to be distributed evenly. Considerable arterial pCO2 changes (up to 20 torr) resulted in but small pO2 in the brain tissue (about 5 torr). The data obtained corroborate the idea of the CO2 important role in regulation of cerebral circulation.
D002196:Capillaries / Q000502:physiology*; D002245:Carbon Dioxide / Q000032:analysis; D002540:Cerebral Cortex / Q000098:blood supply* / Q000378:metabolism; D008959:Models, Neurological; D010100:Oxygen / Q000032:analysis; D010101:Oxygen Consumption
D002245:Carbon Dioxide; D010100:Oxygen
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