Fine structure of chemosensitive cells (glomus caroticum) in tissue culture.
Cells of the carotid body of both embryonic and 1 to 2-d-old rabbits were cultured in monolayer in primary tissue culture. The cells grew in their original association of type I and type II cells. The fine structure of both cell types was similar to that in vivo. Even after one week in culture their morphological characteristics, such as the dense-cored vesicles, were preserved. The prolonged synthesis of catecholamines in culture and the formation of new granular vesicles is discussed.
D000818:Animals; D000831:Animals, Newborn; D002344:Carotid Body / Q000196:embryology / Q000648:ultrastructure*; D002395:Catecholamines / Q000096:biosynthesis; D046508:Culture Techniques; D009940:Organoids / Q000648:ultrastructure; D011817:Rabbits; D014022:Tissue Survival
D002395:Catecholamines