title: Simple transformation method for predicting plasma drug profiles from dissolution rates.
abstract: A transformation factor is described which related in vitro drug dissolution from a preparation to the corresponding in vivo plasma drug concentrations. This factor, derived from the dissolution profile and the corresponding in vivo plasma concentration of a single formulation, was used to predict plasma concentration profiles of similar formulations simply from dissolution data.
mesh_terms: D008722:Methods; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000097:blood*; D012995:Solubility; D013997:Time Factors
chemical_list: D004364:Pharmaceutical Preparations