[Reflexphotometric determinations of vasoconstriction after topical application of steroids. V. Vasoconstriction phaenomenon and tachyphylaxis after repeated steroid application (author's transl)].
On the basis of reflexphotometrical vasoconstriction tests it is demonstrated, that the intensity of vasoreactions caused by a first topical application of steroids, diminishes rapidly after repeated applications, until there is no response of vessels to a new application. This phaenomenon is know as tachyphylaxis and has been found in all tested glucocorticoids.
D000287:Administration, Topical; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D005938:Glucocorticoids; D006801:Humans; D012867:Skin / Q000098:blood supply* / Q000187:drug effects; D013618:Tachyphylaxis; D014666:Vasomotor System / Q000187:drug effects*
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids
Ergebnisse reflexionsphotometrischer Bestimmungen der Vasoconstriction nach topischer Steroidapplikation. V. Vasoconstrictionsphänomene und Tachyphylaxie nach wiederholter Steroidapplikation