Localization of preprogalanin mRNA in the monkey hippocampal formation.
The existence of neurons expressing preprogalanin mRNA in the monkey hippocampal formation was demonstrated using in situ hybridization of a radio-labelled cRNA probe transcribed from human preprogalanin cDNA. Specific hybridization occurred in neurons of the hilus of the dentate gyrus, fields CA1-3 in Ammon's horn, subiculum, presubiculum, parasubiculum and occasionally in neurons of the entorhinal cortex. These findings suggest that galanin is synthesized by neurons intrinsic to the monkey hippocampal formation.
D000818:Animals; D019004:Galanin; D006624:Hippocampus / Q000033:anatomy & histology / Q000378:metabolism*; D006801:Humans; D017403:In Situ Hybridization; D008252:Macaca fascicularis; D010452:Peptide Biosynthesis; D011498:Protein Precursors / Q000096:biosynthesis*; D015347:RNA Probes; D012333:RNA, Messenger / Q000096:biosynthesis*
D011498:Protein Precursors; D015347:RNA Probes; D012333:RNA, Messenger; D019004:Galanin