title: [Use of sulfonylurea preparations in the treatment of children with diabetes mellitus].
abstract: Compensation with normoglycemia and aglycoseurea for periods of from 6 months to 6 years was reached in 53 patients suffering from manifest diabetes mellitus, as a result of application of sulphanilurea preparations. Of this number 34 children were under insulin therapy before the beginning of sulphanilamide treatment. In 8 cases sulphanilurea preparations were cancelled with persistence of stable compensation; in 5 of them there occured normalization of GTT and in 2 GTT became doubtful. A necessity of using insulin occurred later in 21 of 53 patients (in 3 temporarily and in 18 -- constantly) as a result of intercurrent diseases, stress situations or frequent coarse breaks in the diet.
mesh_terms: D000293:Adolescent; D001645:Biguanides / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D002747:Chlorpropamide / Q000008:administration & dosage / Q000627:therapeutic use*; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D014044:Tolbutamide / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D001645:Biguanides; D014044:Tolbutamide; D002747:Chlorpropamide
vernacular_title: Primenenie preparatov sul'fanilmocheviny pri lechenii deteĭ, bol'nykh sakharnym diabetom