Techniques for positron scintigraphy of the brain.
Positron scintigrams were obtained in normal subjects and in patients with intracranial tumors and cerebral vascular disease, using a multicrystal positron camera. The radiopharmaceuticals were 68Ga complexed with adenosine triphosphate (68Ga-ATP), 13N-ammonia (13NH3), and 15O2. Six clinical cases are described to illustrate the different cerebral distributions of intravenously administered 68Ga-ATP, 13NH3, and inhaled 15O2. The possible value of these agents in the study of cerebral metabolism and in differential diagnosis of intracranial disease is discussed.
D000230:Adenocarcinoma / Q000175:diagnosis; D000255:Adenosine Triphosphate; D000328:Adult; D000368:Aged; D000641:Ammonia; D001254:Astrocytoma / Q000175:diagnosis; D001932:Brain Neoplasms / Q000175:diagnosis*; D002561:Cerebrovascular Disorders / Q000175:diagnosis*; D005260:Female; D005710:Gallium Radioisotopes; D005910:Glioma / Q000175:diagnosis; D006801:Humans; D008297:Male; D008579:Meningioma / Q000175:diagnosis; D008875:Middle Aged; D009442:Neurilemmoma / Q000175:diagnosis; D009590:Nitrogen Radioisotopes; D010104:Oxygen Radioisotopes; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis; D011877:Radionuclide Imaging / Q000379:methods*; D000159:Vestibulocochlear Nerve
D005710:Gallium Radioisotopes; D009590:Nitrogen Radioisotopes; D010104:Oxygen Radioisotopes; D000641:Ammonia; D000255:Adenosine Triphosphate