[Effect of blood serum from schizophrenic patients and from normal donors on DNA synthesis in lymphocytes].
The number of DNA-synthesizing lymphocytes in the phytohemagglutinin (PHA)-stimulated cultures of the peripheral blood of schizophrenic patients was determined. Under the mentioned conditions the number of DNA-synthesizing lymphocytes of the schizophrenic patients was 18% less than in the cultures of healthy donors. When the PHA-treated lymphocytes of normal donors were incubated with the serum of schizophrenic patients the number of lymphocytes capable of synthesizing DNA in the presence of PHA fell by 21%.
D004247:DNA / Q000096:biosynthesis*; D006801:Humans; D037102:Lectins / Q000494:pharmacology; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D012559:Schizophrenia / Q000097:blood*
D037102:Lectins; D004247:DNA
Vliianie syvorotki krovi bol'nykh shizofrenieĭ i zdorovykh donorov na sintez DNK v limfotsitakh