Isoniazid inactivation in Black patients with tuberculosis.
A 27% incidence of slow INH inactivator (acetylator) status was observed in a group of 100 Black tuberculotic patients. It is suggested that the incidence of INH toxicity may be high in this group of patients and that clinical cognisance of this problem is desirable.
D000107:Acetylation; D000328:Adult; D000368:Aged; D044383:Black People; D005260:Female; D006207:Half-Life; D006801:Humans; D007538:Isoniazid / Q000097:blood*; D008297:Male; D008875:Middle Aged; D013019:South Africa; D014397:Tuberculosis, Pulmonary / Q000097:blood*
D007538:Isoniazid