Primary hyperparathyroidism in a dog.
Anorexia, severe skeletal demineralization, and muscular weaknesss developed in a 9 year-old Collie. Hypercalcemia, hypophosphatemia, and nephrocalcinosis were found on clinical evaluation. The surgical removal of a parathyroid adenoma was followed by profound hypocalcemia that was unresponsive to calcium therapy, and the dog died. The persistent hypocalcemia was attributed to increased deposition of calcium in mineral-deficient bone.
D000236:Adenoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D000818:Animals; D004283:Dog Diseases / Q000473:pathology / Q000601:surgery; D004285:Dogs; D005260:Female; D006961:Hyperparathyroidism / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D010282:Parathyroid Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary