[Role of different regions of the hypothalamus in regulating the hypophyseal-adrenal cortex system in rats].
The effect of electrical stimulation of various structures of the medial hypothalamus on the corticosterone level in the peripheral blood was studied in rats with preliminarily destroyed individual areas of the hypothalamus. Injury of various structures of the medial hypothalamus led the first days after the operation to reduction of the response to the stimulation. Two-three weeks after destruction of the anterior and the middle portions of the hypothalamus reactivity of the hypophyseo-adrenocortical system was restored, although not always completely. Only in destruction of the premamillary nuclei there was no restoration of the reaction. A conclusion was drawn that the area of the posterior hypothalamus was of great necessity for functional regulation of the hypophysis-adrenal cortex system.
D000302:Adrenal Cortex / Q000502:physiology; D000305:Adrenal Cortex Hormones / Q000097:blood; D000311:Adrenal Glands; D000818:Animals; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D007031:Hypothalamus / Q000502:physiology*; D007032:Hypothalamus, Anterior / Q000502:physiology; D007033:Hypothalamus, Middle / Q000502:physiology; D007034:Hypothalamus, Posterior / Q000502:physiology; D008297:Male; D009929:Organ Size; D010913:Pituitary-Adrenal System / Q000502:physiology*; D051381:Rats; D013997:Time Factors
D000305:Adrenal Cortex Hormones
Rol' razlichnykh oblasteĭ gipotalamusa v reguliatsii sistemy gipofiz-kora nadpochechnikov u krys