Polydactyly: report of a large kindred.
The occurrence of polydactyly in a 33-year-old woman with a patent ductus arteriosus stimulated a study of her family. Four generations of her kindred were examined. No other case of congenital heart disease was discovered, but a large number of individuals with polydactyly were found. Inheritance of this trait is autosomal dominant.
D000015:Abnormalities, Multiple / Q000235:genetics*; D000328:Adult; D002875:Chromosomes; D004374:Ductus Arteriosus, Patent / Q000150:complications; D005260:Female; D005385:Fingers / Q000002:abnormalities*; D005799:Genes, Dominant; D006801:Humans; D010375:Pedigree; D014034:Toes / Q000002:abnormalities*