[Cerebrospinal fluid phospholipids and cerebrosides in several demyelinating diseases].
The author reports of the achieved results in a quantitative study of general lipids, phospholipids and cerebrosides in the CSF of 37 patients with demyelinating diseases, of 11 patients with vascular brain pathology and 7 with Van Bogart's panencephalitis. The control group consisted of 14 patients without focal lesions of the nervous system, with normal CSF indices. In demyelinating diseases there was a significant increase in the content of kephalines and cerebrosides. In Van Bogart's panencephalitis there was a much higher increase of kephalines, general lipids and phospholipids. In vascular brain disorders there was a moderate increase of all lipids. The possible pathochemical mechanisms of the depicted changes in the content of the lipids in the CSF are discussed.
D000293:Adolescent; D000328:Adult; D002554:Cerebrosides / Q000134:cerebrospinal fluid; D002556:Cerebrospinal Fluid Proteins / Q000134:cerebrospinal fluid; D002561:Cerebrovascular Disorders / Q000134:cerebrospinal fluid; D003711:Demyelinating Diseases / Q000134:cerebrospinal fluid*; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000134:cerebrospinal fluid; D005260:Female; D006801:Humans; D008055:Lipids / Q000134:cerebrospinal fluid*; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid; D010714:Phosphatidylethanolamines / Q000134:cerebrospinal fluid; D010743:Phospholipids / Q000134:cerebrospinal fluid; D013344:Subacute Sclerosing Panencephalitis / Q000134:cerebrospinal fluid
D002554:Cerebrosides; D002556:Cerebrospinal Fluid Proteins; D008055:Lipids; D010714:Phosphatidylethanolamines; D010743:Phospholipids
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