Incorporation of 3H-dibromodulcitol and 3H-dianhydrodulcitol into ascites tumor cells. Autoradiographic study.
The incorporation of 3H-Dibromodulcitol and 3H-Dianhydrodulcitol into S37 ascites tumor cells has been studied with autoradiography. Both drugs war incorporated very rapidly into the cells. The labeling of nucleus was higher than that of cytoplasm. A slight accumulation of grains was found above the condensed chromatin and along the membranes. The uptake of DAD has been more intensive than that of DBD.
D000818:Animals; D001345:Autoradiography; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism* / Q000473:pathology; D002454:Cell Differentiation; D004376:Galactitol / Q000378:metabolism*; D051379:Mice; D008854:Microscopy, Electron; D008936:Mitolactol / Q000378:metabolism*; D008938:Mitosis; D013402:Sugar Alcohols / Q000378:metabolism*; D014316:Tritium
D013402:Sugar Alcohols; D014316:Tritium; D004376:Galactitol; D008936:Mitolactol