[The effect of atherogenic diet on the entering of albumin into surviving segments of rabbit aortic wall].
Damage to the endothelial cells in the early phase of atherosclerosis is of essential importance. Presence of an anhomogen layer of endothelial cells revealed in vivo, represents an early lesion of the area of vessel well influenced heavily by haemodinamics. Authors have established that entering of albumin into the aortic wall of rabbits exposed to a cholesterin-rich diet in the early phase of atherosclerosis-in vitro-increases, but later on in the advanced phase of the disease decreases, which can be explained by the slow-down of the speed of diffusion into the vessel wall. Accumulation of plasma-constituents in the vessel wall in the early phases of the vascular lesion is caused by the increase of entering of the plasma, in the advanced stages by the slow-down of the speed of diffusion.
D000418:Albumins / Q000378:metabolism*; D000818:Animals; D001011:Aorta / Q000378:metabolism*; D002784:Cholesterol / Q000008:administration & dosage / Q000378:metabolism*; D011817:Rabbits
D000418:Albumins; D002784:Cholesterol
Atherogen diéta hatása túlélö nyúl-aorta szeletek albumin beáramlására