The accumulation pattern of ingested gossypol in selected organs of the rat.
Bound gossypol levels in the spleen and kidney of rats ingesting dietary gossypol (0.98%) varied directly with the feeding intervals of 6, 14, 28 and 35 days. Free gossypol level in the kidney, spleen and lungs increased for 14 days and then tended to decrease as the feeding period was extended.
D000818:Animals; D006072:Gossypol / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D051381:Rats; D013154:Spleen / Q000378:metabolism; D013997:Time Factors
D006072:Gossypol