[Metabolic disorders and plasmorrhagia in myocardial cells following adrenalin damage].
The authors examined serial sections of the myocardium of rats sacrificed at periods of from 1 to 24 hours after adrenalin administration. The results of histoenzymatic reaction to succinic dehydrogenase (a test for cell injury) were compared with the data obtained in fibrin detection by Coons' method. Plasmorrhagia into the irreversibly injured muscle cells had a characteristic appearance in the test with nitro-BT; there proved to be no fibrin in the fibers with fatty dystrophy marked by macrogranular depositions of formazan. A supposition was put forward on different pathogenesis of the reversible and irreversible injuries of the myocardium caused by adrenalin administration.
D000818:Animals; D004837:Epinephrine; D005337:Fibrin / Q000378:metabolism; D006331:Heart Diseases / Q000139:chemically induced* / Q000473:pathology; D006651:Histocytochemistry; D050356:Lipid Metabolism; D008297:Male; D009206:Myocardium / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D051381:Rats; D013385:Succinate Dehydrogenase / Q000378:metabolism
D005337:Fibrin; D013385:Succinate Dehydrogenase; D004837:Epinephrine
Metabolicheskie narusheniia i plazmorragii v miokardial'nye kletki pri ikh adrenalinovom povrezhdenii