title: Simplification of local therapy of psoriasis with 8-methoxypsoralen. Methods and initial results.
abstract: Local 8-methoxypsoralen black-light treatment was carried out on sixty-two patients. For the first time, oil was employed as a preparation base in order to increase the transparency and so the effectiveness of irradiation. Also the need for a descaling pretreatment was avoided. In investigations still being carried out, 27.5% patients showed very good improvement, 48-4% good and 24-2% unsatisfactory results of treatment. In many cases, less than fifteen irradiation sessions were necessary for clinical healing. However, to obtain a uniform pigmentation, additional irradiation proved necessary.
mesh_terms: D004890:Erythema / Q000209:etiology; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008730:Methoxsalen / Q000008:administration & dosage / Q000627:therapeutic use*; D009821:Oils; D009823:Ointment Bases; D010859:Pigmentation Disorders / Q000628:therapy; D011565:Psoriasis / Q000188:drug therapy* / Q000628:therapy; D014467:Ultraviolet Therapy
chemical_list: D009821:Oils; D009823:Ointment Bases; D008730:Methoxsalen