Lateral diffusion of concanavalin A receptors in the plasma membrane of mouse fibroblasts.
Lateral diffusion of receptors binding fluorescein labeled concanavalin A and its succinylated derivative has been measured by bleaching portions of the labeled surface and following return of fluorescence to the bleached spot. Binding of either concanavalin A or its succinylated derivative causes restriction of mobility of the surface receptors for this lectin. The degree of restriction is a function of time after binding the lectin.
D001665:Binding Sites; D002462:Cell Membrane / Q000378:metabolism*; D003208:Concanavalin A / Q000378:metabolism*; D004058:Diffusion; D005452:Fluoresceins; D007739:L Cells / Q000378:metabolism; D011485:Protein Binding; D011506:Proteins / Q000378:metabolism; D011955:Receptors, Drug; D013050:Spectrometry, Fluorescence
D005452:Fluoresceins; D011506:Proteins; D011955:Receptors, Drug; D003208:Concanavalin A