title: [Dynamics of the clinico-pathophysiologic characteristics of psychoses in old age under the influence of azafen].
abstract: A study of singular doses and subsequent maintenance therapy by azafen on the higher nervous activity of mental patients in presenile age (67 cases) revealed that its action depends upon the dosage of the preparation and the nosological syndrome. A depressive involutional psychoses can be controlled by azafen in doses up to 75 mg daily. By dosages of 25 mg azafen reduces or cessates completely the syndrome of changed consciousness due to disorders of brain circulation. An arrest of a depressive syndrome in manic-depressive psychosis in old age can be attained by an introduction of 150-200 mg of azafen daily.
mesh_terms: D000368:Aged; D001714:Bipolar Disorder / Q000188:drug therapy; D003244:Consciousness Disorders / Q000150:complications; D003704:Dementia / Q000188:drug therapy; D003863:Depression / Q000188:drug therapy; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D002537:Intracranial Arteriosclerosis / Q000150:complications; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000188:drug therapy / Q000209:etiology; D010078:Oxazines / Q000008:administration & dosage / Q000627:therapeutic use*; D010879:Piperazines / Q000008:administration & dosage / Q000627:therapeutic use; D011618:Psychotic Disorders / Q000188:drug therapy*
chemical_list: D010078:Oxazines; D010879:Piperazines
vernacular_title: Dinamika kliniko-patofiziologicheskikh osobennosteĭ psikhozov v pozdnem vozraste pod vliianiem azafena