Sequential determination of C-reactive protein in acute childhood pyelonephritis.
Serum CRP levels ranging between 10 and 200 mug/ml were found in 19 patients with acute pyelonephritis. Treatment with antibacterial drugs, to which the bacteria were fully sensitive, resulted in a rapid decrease of the CRP values and very low or trace amounts were attained within a week. In contrast, cases ineffectively treated and/or reinfected showed increasing or slowly decreasing CRP levels. It is suggested that repeated CRP determinations can be used as a diagnostic tool for the rapid detection of cases of acute pyelonephritis in which treatment is ineffective.
D000208:Acute Disease; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002097:C-Reactive Protein / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D011704:Pyelonephritis / Q000097:blood* / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D002097:C-Reactive Protein