Brain natriuretic peptide (BNP)-like immunoreactivity in the central nervous system of the crested newt.
The distribution of brain natriuretic peptide (BNP)-like immunoreactivity (ir) was studied in the brain of a urodele amphibian, the crested newt Triturus carnifex Laur. BNP-like immunoreactive neurons were found mainly in the caudal hypothalamus (retro- and supra-chiasmatic areas) and in the preoptic area. A widespread innervation throughout the brainstem as far as the spinal cord was also observed. By double immunostaining (after section incubation with a-BNP and a-tyrosine hydroxylase-TH-antibodies), close topographical relationships between BNP-like and TH-like immunoreactive neurons within the hypothalamus were found.
Franzoni
M F
MF
Dipartimento di Biologia Animale, Università di Torino, Italy.
Canonaco
M
M
Frova
A
A
Tavolaro
R
R
D000818:Animals; D001923:Brain Chemistry; D001933:Brain Stem / Q000737:chemistry; D005260:Female; D005455:Fluorescent Antibody Technique; D007031:Hypothalamus / Q000737:chemistry / Q000201:enzymology; D007124:Immunoenzyme Techniques; D008297:Male; D020097:Natriuretic Peptide, Brain; D009419:Nerve Tissue Proteins / Q000032:analysis* / Q000276:immunology; D013116:Spinal Cord / Q000737:chemistry; D014319:Triturus; D014446:Tyrosine 3-Monooxygenase / Q000032:analysis / Q000276:immunology
D009419:Nerve Tissue Proteins; D020097:Natriuretic Peptide, Brain; D014446:Tyrosine 3-Monooxygenase