title: The effect of nocotiana tabacum (snuff) on blood pressure and pulse rate of Nigerians.
abstract: Nutritional and environmental factors are now known to affect the blood pressure and pulse rate of man. The present study investigated the effect of nicotiana tabacum on these parameters. Thirty-three male Nigerians (20-68 years) living in Calabar, Nigeria were used for this study. The subjects were treated at three different periods with snuff containing varied concentrations of Natron (0.5g and 10g/100g of snuff) and their systolic and diastolic pressures as well as pulse rate were measured at intervals of 30 minutes up to a maximum of 90 minutes. Each subject served as his own control. There were significant and time-dependent increases in the parameters measured. In addition, the increases were more marked in the absence of Natron than in its presence.
authors.affiliation: Department of Physiology, College of Medical Sciences, University of Calabar, Nigeria.
authors.forename: N N
authors.initials: NN
authors.lastname: Orie
authors.forename: I N
authors.initials: IN
authors.lastname: Ibanga
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects*; D002254:Carbonates / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010947:Plants, Toxic; D014030:Tobacco, Smokeless / Q000009:adverse effects*
chemical_list: D002254:Carbonates; C005686:sodium carbonate