[Frequency of sex chromatin among mental patients].
The frequency of sex chromatin of 2000 cases of mental patients are observed in this paper. The frequency of Y chromatin in male and X chromatin in female was 28.01% and 26.86% respectively, whereas only 16.97% and 17.84% respectively in the control group. The mental patient group is higher than the control group significantly (P < 0.0001). It may be influenced by some psychotropic drugs and the factor of course. Positive X chromatin in the male patients was 8 cases and karyotypes of chromosome was XXY type all. The incidence of XXY type is 0.77% and significant higher than the control group (0.18%, P < 0.01). It suggested that ratio of add one X chromosome in the male mental patients be obviously increased. The authors indicated if this examination be routinely used in clinic that would prevent misdiagnosis and would raise accuracy of diagnosis.
Feng
Z Y
ZY
Tianjin An Ding Psychiatric Hospital.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000235:genetics; D002746:Chlorpromazine / Q000494:pharmacology; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D010546:Perphenazine / Q000494:pharmacology; D012559:Schizophrenia / Q000235:genetics*; D012728:Sex Chromatin / Q000187:drug effects
D010546:Perphenazine; D002746:Chlorpromazine