title: [The use of the zonal electrophoresis of antibiotics in acute destructive cholecystitis complicated by suppurative cholangitis].
abstract: At experimental investigations on 38 adult dogs for studying pharmacokinetics of kanamycin in the bile and liver tissue under the influence of the electric field of constant current, the increase in concentration of the preparation as compared with that in the control group was established. Optimal concentration of kanamycin retained for 14-16 h. Clinical study has shown the high effectiveness of the method for treatment of acute cholangitis suggested.
authors.forename: A V
authors.initials: AV
authors.lastname: Alekseenko
authors.forename: V K
authors.initials: VK
authors.lastname: Patratiĭ
authors.forename: A G
authors.initials: AG
authors.lastname: Iftodiĭ
authors.forename: V V
authors.initials: VV
authors.lastname: Tarabanchuk
authors.forename: N G
authors.initials: NG
authors.lastname: Shcherban
mesh_terms: D000208:Acute Disease; D000818:Animals; D002761:Cholangitis / Q000188:drug therapy* / Q000209:etiology; D002764:Cholecystitis / Q000150:complications / Q000188:drug therapy*; D004285:Dogs; D006801:Humans; D007275:Injections, Intravenous; D007478:Iontophoresis / Q000379:methods*; D007612:Kanamycin / Q000008:administration & dosage* / Q000493:pharmacokinetics; D013997:Time Factors; D014018:Tissue Distribution
chemical_list: D007612:Kanamycin
vernacular_title: Ispol'zovanie zonal'nogo élektroforeza antibiotikov pri ostrom destruktivnom kholetsistite, oslozhnennom gnoĭnym kholangitom.