title: [The effect of dalargin on stress-induced changes in the 5'-nucleotidase activity of the macrophages and in the level of endogenous blood cortisol in mice].
abstract: The action of dalargin, synthetic analogue of leuenkephaline, on stress-induced changes in 5'-nucleotidase activity and endogenous hydrocortisone levels was investigated in mice. It was found that there is a direct relation between the activity of 5'-nucleotidase and the level of hydrocortisone in CBA mice. For C57Bl/6 mice the relation was inverse. Dalargin is able to change the dependence from direct to opposite in CBA mice.
authors.forename: G B
authors.initials: GB
authors.lastname: Kirillicheva
authors.forename: V V
authors.initials: VV
authors.lastname: Mit'kin
authors.forename: M S
authors.initials: MS
authors.lastname: Solov'eva
authors.forename: A A
authors.initials: AA
authors.lastname: Zozulia
authors.forename: M R
authors.initials: MR
authors.lastname: Shurin
authors.forename: S F
authors.initials: SF
authors.lastname: Pshenichkin
authors.forename: G T
authors.initials: GT
authors.lastname: Sukhikh
mesh_terms: D015720:5'-Nucleotidase / Q000097:blood / Q000187:drug effects*; D000818:Animals; D004597:Electroshock / Q000009:adverse effects; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives* / Q000494:pharmacology; D006854:Hydrocortisone / Q000097:blood*; D008264:Macrophages / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D013312:Stress, Physiological / Q000097:blood* / Q000209:etiology; D013997:Time Factors
chemical_list: D016308:Enkephalin, Leucine-2-Alanine; D015720:5'-Nucleotidase; C040996:enkephalin-Leu, Ala(2)-Arg(6)-; D006854:Hydrocortisone
vernacular_title: Vliianie dalargina na stress-indutsirovannoe izmenenie aktivnosti 5'-nukleotidazy makrofagov i urovnia éndogennogo kortizola krovi mysheĭ.