[Processing, targeting and import into the mitochondria and peroxisomes of proteins coded by nuclear genes].
I have herein discussed two gene-enzyme families in maize whose protein products participate to purge toxic oxidants from cells, and are thus of importance to all aerobic organisms. We have demonstrated that plant mitochondria import precursor proteins (i.e., preSOD-3) in a manner analogous to other eukaryotic cells. The "transit peptide" (TP) of preSOD-3 is 31 amino acid long and has similar properties to other reported TPs for mitochondrial and chloroplastic proteins. Import to peroxisomes is uniquely different from that for mitochondria and chloroplasts in that no consensus presequence seems to be involved. Instead, targeting signals seem to be integral parts of peroxisomal proteins.
Scandalios
J G
JG
Department of Genetics, North Carolina State University, Raleigh 27695-7614.
D000595:Amino Acid Sequence; D000818:Animals; D001419:Bacteria / Q000235:genetics; D001483:Base Sequence; D002374:Catalase / Q000235:genetics / Q000378:metabolism; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D017343:Genes, Plant / Q000235:genetics*; D005815:Genetic Code / Q000235:genetics*; D006801:Humans; D051379:Mice; D008830:Microbodies / Q000378:metabolism*; D008928:Mitochondria / Q000378:metabolism*; D008969:Molecular Sequence Data; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D011499:Protein Processing, Post-Translational / Q000235:genetics*; D051381:Rats; D011198:Solanum tuberosum / Q000235:genetics; D013482:Superoxide Dismutase / Q000235:genetics / Q000378:metabolism; D015003:Yeasts / Q000235:genetics; D003313:Zea mays / Q000235:genetics* / Q000378:metabolism
D010940:Plant Proteins; D004247:DNA; D002374:Catalase; D013482:Superoxide Dismutase
Protsessing, adresovanie i importirovanie v mitokhondrii i peroksisomy belkov, kodiruemykh iadernymi genami.