[Pathophysiologic mechanisms of cardiorespiratory system dysfunction in high school children with chronic obstructive pulmonary diseases].
The basic indices of the cardiorespiratory system function, gas exchange, regional pulmonary functions have been studied. It is stated that a group of children with a higher level of oxygen consumption (hyperergic type) as against a control group is characterized by disorder in permeability of terminal branches of a bronchial tree, by the development of acute obstructive emphysema, increase in alveolar ventilation with relative decrease in minute blood volume, arterial hypoxemia with possible emergence of tissue hypoxia. A decrease in permeability of large bronchi were observed in a group of children with a low level of oxygen consumption (hypoergic type). Due to this decrease the hypoventilation zones appeared. It caused the development of arterial hypoxemia, but a risk of the tissue hypoxia emergence was insignificant.
Seredenko
M M
MM
Portnychenko
V I
VI
Velychko
M I
MI
Lasytsia
O I
OI
D000293:Adolescent; D001775:Blood Circulation; D001784:Blood Gas Analysis; D002319:Cardiovascular System / Q000503:physiopathology*; D015687:Cell Hypoxia; D002648:Child; D006801:Humans; D000860:Hypoxia / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology*; D008173:Lung Diseases, Obstructive / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology*; D010100:Oxygen / Q000502:physiology*; D010101:Oxygen Consumption; D010992:Plethysmography, Impedance; D012129:Respiratory Function Tests
D010100:Oxygen
Patofiziologichni mekhanizmy porushennia funktsii kardiorespiratornoĭ systemy u diteĭ serednógo shkilńogo viku z khronichnymy obstruktyvnymy zakhvoriuvanniamy legen.