title: [Clinico-diagnostic value of the immunologic parameters of blood and cerebrospinal fluid in patients with a tumor of the posterior cranial fossa].
abstract: In 37 patients with a tumor of the posterior cranial fossa, the immunologic indices of the spinal fluid, blood serum and tumor contents were studied. It was established that changes in the immunologic indices (intrathecal synthesis of IgG and IgA, production of the immunoregulatory factors of cellular immunity, severity of lesion of the brain structures) depended on a degree of tumor anaplasia and age of the patients. These findings can be used for diagnosis of cerebral neoplasms of different degree of malignancy with regard for the age of a patient.
authors.forename: V A
authors.initials: VA
authors.lastname: Rudenko
authors.forename: N I
authors.initials: NI
authors.lastname: Lisianyĭ
authors.forename: E I
authors.initials: EI
authors.lastname: Skobskiĭ
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis*; D001932:Brain Neoplasms / Q000097:blood / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003388:Cranial Fossa, Posterior; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood / Q000134:cerebrospinal fluid; D007074:Immunoglobulin G / Q000097:blood / Q000134:cerebrospinal fluid; D007075:Immunoglobulin M / Q000097:blood / Q000134:cerebrospinal fluid; D008875:Middle Aged; D009367:Neoplasm Staging; D010751:Phosphopyruvate Hydratase / Q000097:blood / Q000134:cerebrospinal fluid
chemical_list: D014408:Biomarkers, Tumor; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D010751:Phosphopyruvate Hydratase
vernacular_title: Kliniko-diagnosticheskoe znachenie immunologicheskikh pokazateleĭ krovi i spinnomozgovoĭ zhidkosti u bolńykh s opukholíu zadneĭ cherepnoĭ iamki.