title: Changes in human plasma dopamine-beta-hydroxylase activity after ketamine and halothane anesthesia.
abstract: The intravenous administration of ketamine hydrochloride to fifteen patients undergoing surgery produced no change in circulating plasma dopamine-beta-hydroxylase (DBH), although it produced a significant increase both in systolic blood pressure (BP) and diastolic BP during anesthesia. Halothane anesthesia that depress BP also produced no change in plasma DBH activity.
authors.affiliation: Department of Pharmacology, Faculty of Medicine, Cumhuriyet University Sivas, Turkey.
authors.forename: L
authors.initials: L
authors.lastname: Akbaş
authors.forename: Y
authors.initials: Y
authors.lastname: Sarioglu
authors.forename: A
authors.initials: A
authors.lastname: Aker
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D002648:Child; D002675:Child, Preschool; D004299:Dopamine beta-Hydroxylase / Q000097:blood / Q000187:drug effects*; D006221:Halothane / Q000494:pharmacology*; D006801:Humans; D007223:Infant; D007649:Ketamine / Q000494:pharmacology*; D008875:Middle Aged
chemical_list: D007649:Ketamine; D004299:Dopamine beta-Hydroxylase; D006221:Halothane