title: [Relationship between metabolic changes in regional blood and tissues in ischemia of the extremities].
abstract: The authors examined 56 patients with obliterating diseases (OD) of arteries of the lower extremities and conducted experiments on 97 male albino rats. In patients with OD the lactate content in the regional venous blood of the involved extremity increases proportionally to the severity of ischemia. No essential changes occur in the concentration of ATP and glucose. In rats with transitory ischemia of the extremities the lactate level in venous blood increases in the absence of changes of the ATP and glucose content; reduced concentration of ATP and glycogen was encountered in the ischemic muscles of the extremities. The mechanisms and significance of the disorders of metabolic parameters in ischemia are discussed.
authors.forename: G K
authors.initials: GK
authors.lastname: Zoloev
authors.forename: V I
authors.initials: VI
authors.lastname: Ponurovskiĭ
authors.forename: V A
authors.initials: VA
authors.lastname: Rakiatin
authors.forename: E S
authors.initials: ES
authors.lastname: Argintaev
authors.forename: M G
authors.initials: MG
authors.lastname: Shil'nikov
mesh_terms: D000328:Adult; D000818:Animals; D001158:Arteries; D005121:Extremities / Q000098:blood supply*; D006801:Humans; D007511:Ischemia / Q000097:blood / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D051381:Rats; D017208:Rats, Wistar; D012039:Regional Blood Flow
vernacular_title: Sootnoshenie mezhdu metabolicheskimi izmeneniiami v regionarnoĭ krovi i tkaniiakh pri ishemii konechnosti.