title: Protocol for studying depth of anesthesia using the spectral edge frequency.
abstract: The preliminary results of a multicenter study designed to determine the utility of the processed EEG in combination with heart rate and blood pressure for estimating anesthetic depth are reported. The study is planned to include 1,000 ASA I, II, and III patients undergoing surgery with at least a 60-minute duration of anesthesia. The preliminary results indicate that the use of EEG and clinical signs may provide better control of anesthetic depth. The study design provides ideal conditions for determining whether spectral edge frequency is a useful criterion for management of routine general anesthesia in a typical clinical environment.
authors.affiliation: Department of Anesthesiology, University Medical School of Mainz, Germany.
authors.forename: M V
authors.initials: MV
authors.lastname: Schaefer
authors.forename: M S
authors.initials: MS
authors.lastname: Rugeles
authors.forename: G
authors.initials: G
authors.lastname: Gurman
authors.forename: H P
authors.initials: HP
authors.lastname: Moecke
authors.forename: P M
authors.initials: PM
authors.lastname: Osswald
authors.forename: D
authors.initials: D
authors.lastname: Olthoff
authors.forename: E
authors.initials: E
authors.lastname: Voigt
authors.forename: W F
authors.initials: WF
authors.lastname: Dick
mesh_terms: D000768:Anesthesia, General; D000769:Anesthesia, Inhalation; D004569:Electroencephalography; D006801:Humans; D016343:Monitoring, Intraoperative / Q000379:methods*