Slow potentials activated by afferent and direct stimulation in spinal interneurons of laminae III-V.
Stimulation of hairy skin afferent fibers and/or direct depolarizing current injection initiates persistent changes in membrane potential (slow potentials), lasting up to 1 min or longer, in some deep dorsal horn neurons. Intracellular staining with horseradish peroxidase shows that these cells are interneurons, suggesting that slow potentials modulate moment-to-moment impulse transmission in local spinal circuits.
Schneider
S P
SP
Department of Physiology, University of North Carolina, Chapel Hill 27599-7545.
D000344:Afferent Pathways / Q000502:physiology*; D000818:Animals; D001370:Axonal Transport; D001369:Axons / Q000502:physiology; D006224:Cricetinae; D004558:Electric Stimulation; D005071:Evoked Potentials; D006197:Hair / Q000294:innervation; D006735:Horseradish Peroxidase; D066298:In Vitro Techniques; D007395:Interneurons / Q000502:physiology*; D008564:Membrane Potentials; D009412:Nerve Fibers / Q000502:physiology; D012867:Skin / Q000294:innervation*; D013116:Spinal Cord / Q000502:physiology*
D006735:Horseradish Peroxidase