title: [Indications for the use of platelets, plasma and anti-hemorrhagic drugs].
abstract: During the last years, the use of hemoderivatives has largely increased. Their use carries a high risk for post-transfusion reactions and for transmission of severe infectious diseases. In a high percentage of cases the use of these compounds is inadequate. At the present time there are pharmacologic (desmopressin, antifibrinolytics, vitamin K) and nonpharmacologic strategies (autotransfusion, hemodilution, intra and postoperative recovery of blood) directed to avoid or to decrease the need for transfusion. We review all these strategies and we propose some criteria for transfusion of plasma and platelets, as well as attitudes for particular situations.
authors.affiliation: Servicio de Hematología y Hemoterapia, Hospital de la Santa Creu i Sant Pau, Barcelona.
authors.forename: J
authors.initials: J
authors.lastname: Mateo
authors.forename: E
authors.initials: E
authors.lastname: Muñiz-Díaz
authors.forename: J
authors.initials: J
authors.lastname: Fontcuberta
authors.forename: P
authors.initials: P
authors.lastname: Madoz
mesh_terms: D000933:Antifibrinolytic Agents / Q000627:therapeutic use*; D016913:Blood Component Transfusion; D016063:Blood Loss, Surgical; D001792:Blood Platelets / Q000502:physiology; D001802:Blood Substitutes; D001803:Blood Transfusion; D001804:Blood Transfusion, Autologous; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use*; D006438:Hemodilution; D006470:Hemorrhage / Q000188:drug therapy / Q000517:prevention & control / Q000628:therapy*; D006474:Hemorrhagic Disorders / Q000209:etiology / Q000378:metabolism / Q000628:therapy; D006488:Hemostasis, Surgical / Q000379:methods; D006801:Humans; D010949:Plasma; D065227:Transfusion Reaction
chemical_list: D000933:Antifibrinolytic Agents; D001802:Blood Substitutes; D003894:Deamino Arginine Vasopressin
vernacular_title: Indicaciones para el uso de plaquetas, plasma y fármacos antihemorrágicos.