title: [Clinical evaluation of cefprozil granules in pediatric field].
abstract: Cefprozil (CFPZ, BMY-28100) granules were administered to 20 children with bacterial infections: acute tonsillitis 8, acute bronchitis 10, purulent lymphadenitis 1, urinary tract infection 1. Daily doses ranged 29-50 mg/kg. The drug was given orally, 3 times a day and the durations of administration were 5 to 9 days. Clinical efficacies were excellent in 16 cases and good in 4 cases, hence the overall efficacy rate was 100%. No side effects were observed in any of these cases. As for abnormal laboratory test values, thrombocytosis was observed in 1 case. From the above results, we consider CFPZ granules to be a useful drug for the treatment of pediatric patients with various bacterial infections.
authors.affiliation: Department of Pediatrics, Kagawa Children Hospital, National Sanatrium.
authors.forename: S
authors.initials: S
authors.lastname: Furukawa
authors.forename: T
authors.initials: T
authors.lastname: Okada
mesh_terms: D000284:Administration, Oral; D000367:Age Factors; D001419:Bacteria / Q000302:isolation & purification; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D002511:Cephalosporins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D013922:Thrombocytosis / Q000139:chemically induced; D000097670:Cefprozil
chemical_list: D002511:Cephalosporins; D000097670:Cefprozil