Effect of dietary chitin on cholesterol absorption and metabolism in rats.
The effect of chitin at the level of 5% in the diet on cholesterol absorption and metabolism was studied in Wistar rats fed on diet containing beef tallow (7%) and cholesterol (1%). When compared with pair-fed controls, rats fed on diet containing chitin had: (1) similar weight gain and feed efficiency, (2) lower apparent protein digestibility, (3) equivalent liver steatosis, (4) reduced levels of liver triglycerides and cholesterol, (5) similar levels of serum and fecal cholesterol, (6) higher excretion of triglycerides in feces.
Zacour
A C
AC
Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Brazil.
Silva
M E
ME
Cecon
P R
PR
Bambirra
E A
EA
Vieira
E C
EC
D000042:Absorption; D000818:Animals; D002417:Cattle; D002686:Chitin / Q000008:administration & dosage / Q000494:pharmacology*; D002784:Cholesterol / Q000378:metabolism*; D002791:Cholesterol, Dietary / Q000494:pharmacology; D004040:Dietary Carbohydrates / Q000008:administration & dosage / Q000494:pharmacology*; D008099:Liver / Q000033:anatomy & histology / Q000187:drug effects / Q000378:metabolism; D008297:Male; D008460:Meat; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D014280:Triglycerides / Q000378:metabolism; D015430:Weight Gain / Q000187:drug effects
D002791:Cholesterol, Dietary; D004040:Dietary Carbohydrates; D014280:Triglycerides; D002686:Chitin; D002784:Cholesterol