title: [Naming difficulties seen in a case of alexia with agraphia caused by a left postero-inferior temporal lesion].
abstract: A 71-year-old right-handed man presented writing and reading difficulties as well as naming difficulties. Neuropsychological examinations revealed mild fluent type aphasia accompanied by alexia and agraphia predominantly affecting kanji and also severe naming difficulties. Brain MRI showed cerebral subcortical hemorrhage extending from the anterior one-third of the left temporal lobe to the temporo-occipital junction involving the fusiform gyrus. The analysis of the several reported cases with severe alexia with agraphia for kanji including ours revealed a close correlation between the severity of kanji writing disturbances and that of naming difficulties. It was also shown that cases with severe naming difficulties had lesion extending anteriorly to the anterior middle temporal gyrus or medially to the parahippocampal gyrus, suggesting that the disconnection between the parahippocampal gyrus and other cortices including the temporal lobe was essential for production of naming difficulties.
authors.affiliation: Department of Neurology, Japanese Red Cross Medical Center.
authors.forename: K
authors.initials: K
authors.lastname: Sakai
authors.forename: Y
authors.initials: Y
authors.lastname: Sakurai
authors.forename: M
authors.initials: M
authors.lastname: Sakuta
authors.forename: M
authors.initials: M
authors.lastname: Iwata
mesh_terms: D000368:Aged; D000381:Agraphia / Q000209:etiology*; D002543:Cerebral Hemorrhage / Q000150:complications*; D004411:Dyslexia, Acquired / Q000209:etiology*; D006801:Humans; D008297:Male