Hepatosplenic infection caused by Candida parapsilosis in patients with acute leukemia.
Candida parapsilosis is an exceptional agent in hepatosplenic candidosis. Here we report two cases of hepatosplenic infection caused by Candida parapsilosis in two patients with acute leukaemia. Open liver-spleen biopsy and previously minimal exposure to systemic antifungal drugs led to a cultural diagnosis in both patients. This report confirms the importance of an early diagnosis of these diseases in order to undertake appropriate therapeutic regimens.
D'Antonio
D
D
Laboratorio di Microbiologia Clinica-Università degli Studi G. D'Annunzio, Chieti, Italy.
Fioritoni
G
G
Iacone
A
A
Betti
S
S
Fazii
P
P
Dell'Isola
M
M
Di Gianfilippo
R
R
Di Silverio
A
A
Ubezio
S
S
Zeccara
C
C
D000328:Adult; D002177:Candidiasis / Q000150:complications*; D002648:Child; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008107:Liver Diseases / Q000150:complications* / Q000382:microbiology; D008297:Male; D013158:Splenic Diseases / Q000150:complications* / Q000382:microbiology