title: [The antidepressive properties of anaprilin].
abstract: After chronic administration of propranolol (1 and 5 mg/kg, 14 days) to rats time-course of forced swimming changed with the decrease of rhythmical index of depression. The drug attenuated depressogenic properties of reserpine and clonidine. Propranolol antidepressive activity is attributed to blockade cerebral adrenoreceptors.
authors.forename: E B
authors.initials: EB
authors.lastname: Arushanian
authors.forename: E V
authors.initials: EV
authors.lastname: Beĭer
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003000:Clonidine / Q000494:pharmacology; D003863:Depression / Q000188:drug therapy / Q000209:etiology; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004347:Drug Interactions; D008297:Male; D011433:Propranolol / Q000627:therapeutic use*; D051381:Rats; D012110:Reserpine / Q000494:pharmacology; D013550:Swimming; D013997:Time Factors
chemical_list: D000928:Antidepressive Agents; D012110:Reserpine; D011433:Propranolol; D003000:Clonidine
vernacular_title: Ob antidepressivnykh svoĭstvakh anaprilina.