[The properties of the glucocorticoid-sensitive alkaline proteinases of target organs in rats].
The preliminary characterization of glucocorticoid-sensitive alkaline proteinases of rat thymus and liver was carried out. The role of active serine and cysteine residues in proteolysis was estimated. The influence of Ca++, Mg++, Fe++, Fe , Cu++, EDTA and EGTA on enzymes activity was studied. It is shown that alkaline proteinases of thymus and liver have similar properties, but are not completely identical.
Ogurtsov
S I
SI
Dukhanin
A S
AS
Mitroshina
S Iu
SIu
D000818:Animals; D003907:Dexamethasone / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D010450:Endopeptidases / Q000187:drug effects* / Q000378:metabolism; D004789:Enzyme Activation / Q000187:drug effects; D007202:Indicators and Reagents; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D051381:Rats; D012979:Sodium Radioisotopes; D013696:Temperature; D013950:Thymus Gland / Q000187:drug effects* / Q000201:enzymology
D007202:Indicators and Reagents; D012979:Sodium Radioisotopes; D003907:Dexamethasone; D010450:Endopeptidases
Svoĭstva gliukokortikoid-chuvstvitel'nykh shchelochnykh proteinaz organov-misheneĭ krys.