title: [Post-anesthesia rhabdomyolysis syndrome following muscular stress. 2 case reports].
abstract: Effort rhabdomyolysis is a syndrome which takes the form of a pathology with different etiopathogenetic stages. General anesthesia may trigger off acute muscular cytolysis which is probably influenced by the inflammatory surgical pathology itself. The observation of two cases of post-anesthetic rhabdomyolysis following muscular stress suggest that the exhaustion of muscle energy reserves and the consequent alteration of the ATP/ADP ratio may act as a trigger mechanism for this syndrome. Its close relationship with malignant hyperthermia makes a precise anamnesis vitally important, especially in relation to recent intense physical effort in patients undergoing emergency surgery for acute pathologies.
authors.affiliation: Regione Lombardia, USSL n. 1, Servizio di Anestesia e Rianimazione, Ospedale Civile Castel San Giovanni, Piacenza.
authors.forename: P
authors.initials: P
authors.lastname: Grosso
authors.forename: P L
authors.initials: PL
authors.lastname: Petrini
authors.forename: R
authors.initials: R
authors.lastname: Massei
mesh_terms: D000293:Adolescent; D000328:Adult; D000768:Anesthesia, General / Q000009:adverse effects*; D015444:Exercise; D006801:Humans; D008297:Male; D009132:Muscles; D012206:Rhabdomyolysis / Q000209:etiology*; D013312:Stress, Physiological / Q000150:complications*
vernacular_title: Sindrome da rabdomiolisi post-anestetica in seguito a stress muscolare. Descrizione di due casi.