title: Severe aseptic synovitis of the knee after biodegradable internal fixation. A case report.
abstract: Biodegradable rods made of polyglycolide (Dexon, Biofix) or lactide-glycolide copolymer (Vicryl) have been used for the past 5 years for internal fixation of a variety of fractures and osteotomies (Böstman et al. 1989, 1990b). Experience from using such rods for fixation of intraarticular osteochondral lesions seems to be less extensive. We report a case of severe synovial reaction to biodegradable rods used for fixation of osteochondritis dissecans of the knee and discuss possible reasons for the increased risk of foreign-body reactions when these rods are used intraarticularly.
authors.affiliation: Lund University Hospital, Department of Orthopedics, Sweden.
authors.forename: T
authors.initials: T
authors.lastname: Fridén
authors.forename: U
authors.initials: U
authors.lastname: Rydholm
mesh_terms: D000328:Adult; D001673:Biodegradation, Environmental; D003165:Complement System Proteins / Q000302:isolation & purification; D005549:Foreign-Body Reaction / Q000209:etiology*; D006801:Humans; D007719:Knee Joint; D008297:Male; D010008:Osteochondritis Dissecans / Q000601:surgery*; D011100:Polyglycolic Acid / Q000009:adverse effects* / Q000378:metabolism; D000074402:Synovectomy; D013582:Synovial Fluid / Q000276:immunology; D013583:Synovial Membrane / Q000473:pathology; D013585:Synovitis / Q000209:etiology* / Q000473:pathology
chemical_list: D011100:Polyglycolic Acid; D003165:Complement System Proteins