Effect of oral curcumin administration on serum peroxides and cholesterol levels in human volunteers.
The effect of curcumin administration in reducing the serum levels of cholesterol and lipid peroxides was studied in ten healthy human volunteers, receiving 500 mg of curcumin per day for 7 days. A significant decrease in the level of serum lipid peroxides (33%), increase in HDL Cholesterol (29%), and a decrease in total serum cholesterol (11.63%) were noted. As curcumin reduced serum lipid peroxides and serum cholesterol, the study of curcumin as a chemopreventive substance against arterial diseases is suggested.
Soni
K B
KB
Amala Cancer Research Centre, Amala Nagar, Trichur.
Kuttan
R
R
D000284:Administration, Oral; D000328:Adult; D001835:Body Weight / Q000187:drug effects; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D003474:Curcumin / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008054:Lipid Peroxides; D014280:Triglycerides; D002784:Cholesterol; D003474:Curcumin