Impacts of the evolutionary concepts of cancer on the study of human diseases.
Evolutionary concepts of cancer (Okuyama and Mishina 1984; 1990) have already been found useful in understanding carcinogenesis and anti-cancer defense lines in the body and various cancer attributes. The concept of endosymbiotic disorders gave an impact upon the science of internal medicine leading to discovery of amitosis in Reed-Sternberg cells, a primitive eukaryotism (Okuyama 1991a). A novel concept of vasogenic necrosis was also developed for such diseases of Perthes' disease, cerebral vascular diseases and myocardial infarction: costs of bipedalitic evolution in man.
Okuyama
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Department of Radiology, Tohoku Rosai Hospital, Sendai, Japan.
D005075:Biological Evolution; D004194:Disease / Q000209:etiology*; D006801:Humans; D009369:Neoplasms / Q000209:etiology*