[Effects of biomicrosphere on the cochlear blood flow, blood pressure and heart rate in guinea pigs].
Cochlear blood flow (CBF) in guinea pigs was measured by Laser Doppler flowmeter and biomicrosphere method. The effects of dosages of biomicrospheres and time factor on the CBF, blood pressure and heart rate were observed. The findings suggest that 9 x 10(6). 10.5 x 10(6) biomicrospheres may be most suitable for measuring CBF with biomicrosphere method, and some physiological parameters of the guinea pig must be taken down within 2-10 minutes after microsphere injection.
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R Z
RZ
Union Hospital, Tong Ji Medical University, Wuhan.
D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure; D003051:Cochlea / Q000098:blood supply*; D005260:Female; D006168:Guinea Pigs; D006339:Heart Rate; D017078:Laser-Doppler Flowmetry; D008297:Male; D008863:Microspheres; D012039:Regional Blood Flow / Q000502:physiology