title: [Inactivating action of bacteria on the lipolytic activity of solizyme and its prevention by antibacterial drugs].
abstract: Bacteria capable of producing exoproteases were isolated from intermediate products of microbial lipase. The proteolytic enzymes produced by the bacteria were able to inactivate 20 to 80 per cent of the lipase depending on the time of incubation, protease production by the contaminating microbe and the experimental conditions. Antibiotics and antiseptics inhibiting growth of bacteria prevented or limited their inactivating action on lipase. Except catamine, the tested antimicrobial drugs as such had no effect on lipase activity.
authors.forename: E M
authors.initials: EM
authors.lastname: Malkova
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D001419:Bacteria / Q000201:enzymology*; D008049:Lipase / Q000037:antagonists & inhibitors*; D008066:Lipolysis / Q000187:drug effects*; D010447:Peptide Hydrolases / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; C081378:solysime; D008049:Lipase; D010447:Peptide Hydrolases
vernacular_title: Inaktiviruiushchee deĭstvie bakteriĭ na lipoliticheskuiu aktivnost' solizima i ego preduprezhdenie antibakterial'nymi preparatami.