[In vitro measurement of antibacterial activities of topical antibacterial creams].
A new method of in vitro measurement of antibacterial activity of different antimicrobial creams is introduced in this paper. The tested cream in known quantity is uniformed suspended in a solid medium, and bacteria of known quantity are inoculated. The result is expressed in MIC. In this observation, four creams were tested against 3 bacteria. It is the authors impression that the new method is better than the traditional disc method, as it reflects better the actual antibacterial activity of the drug in a cream base. It is helpful in selecting an effective drug or to evaluate the effectiveness of certain drugs in clinical practice.
Zhang
M Q
MQ
Ningbo Second Hospital.
D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009824:Ointments; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012837:Silver Sulfadiazine / Q000008:administration & dosage / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects*
D009824:Ointments; D012837:Silver Sulfadiazine