title: [Synthesis of N-(2-carboxy-thieno(2,3-b)pyridin-3-yl)amidines by means of reaction of 4-oxo-4H-pyrido(3',2':4,5)thieno(3,2-d)-1,3-oxazines with primary aliphatic amines].
abstract: The title compounds were synthesized by the reaction of tricyclic compounds of structure B with primary aliphatic amines under different conditions and useful isolation methods in good yields. These compounds showed an acceptable antianaphylactic activity.
authors.affiliation: Sektion Biowissenschaften der Universität Leipzig, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Vieweg
authors.forename: S
authors.initials: S
authors.lastname: Leistner
authors.forename: G
authors.initials: G
authors.lastname: Wagner
mesh_terms: D000578:Amidines / Q000138:chemical synthesis* / Q000494:pharmacology; D000588:Amines / Q000737:chemistry; D000818:Animals; D010078:Oxazines / Q000737:chemistry*; D010323:Passive Cutaneous Anaphylaxis / Q000187:drug effects*; D011725:Pyridines / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats
chemical_list: D000578:Amidines; D000588:Amines; D010078:Oxazines; D011725:Pyridines
vernacular_title: Synthese von N-(2-carboxy-thieno(2,3-b)pyridin-3-yl)amidinen durch Reaktion von 4-Oxo-4H-pyrido(3',2':4,5)thieno(3,2-d)-1,3-oxazinen mit primären aliphatischen Aminen.