title: Subtotal splenectomy in Gaucher's disease: towards a definition of critical splenic mass.
abstract: Partial splenectomy is currently the favoured surgical approach for Gaucher's disease. Preservation of splenic tissue is indicated to prevent susceptibility to overwhelming postsplenectomy sepsis, to delay the massive deposition of glucocerebroside in the liver and bones, and to relieve symptoms of hypersplenism. Controversial issues and technical problems related to partial splenectomy for Gaucher's disease are discussed and a definition of critical splenic mass considered.
authors.affiliation: Department of Pediatric Surgery, Beilinson Medical Center, Petah, Tiqva, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Zer
authors.forename: E
authors.initials: E
authors.lastname: Freud
mesh_terms: D005776:Gaucher Disease / Q000473:pathology / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control; D013154:Spleen / Q000473:pathology; D013156:Splenectomy / Q000379:methods*