Chloramphenicol-resistant typhoid fever: an emerging problem in Oman.
Until recently multiply drug-resistant Salmonella typhi was uncommon in the Sultanate of Oman. In 1990 the first isolate of chloramphenicol-resistant S. typhi from an Indian expatriate was reported. In 1991, 58 cases of typhoid fever were diagnosed, of whom 19 (33%) were resistant to chloramphenicol. All patients with chloramphenicol-resistant S. typhi are either Indians or Omani with a history of recent travel to India. Chloramphenicol may not be the appropriate blind therapy for such patients. Ciprofloxacin may be the alternative.
Elshafie
S S
SS
Department of Medical Microbiology, College of Medicine, Sultan Qaboos University, Sultanate of Oman.
Rafay
A M
AM
D002702:Chloramphenicol Resistance; D006801:Humans; D009850:Oman; D012485:Salmonella typhi / Q000187:drug effects*; D014435:Typhoid Fever / Q000382:microbiology*