[2-Acetylaminofluorene--a model mutagen and hepatocarcinogen. Characterization of its interactions with DNA].
2-Aminofluorene and its derivative 2-acetylaminofluorene are well known mutagens and carcinogens. Molecular mechanisms concerning their mutagenic and cancer promotion activity during hepatocarcinogenesis are summarized in the paper.
Widłak
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Zakład Biologii Nowotworów Instytutu Onkologii, Gliwicach.
D015073:2-Acetylaminofluorene / Q000737:chemistry / Q000633:toxicity*; D000818:Animals; D001483:Base Sequence / Q000187:drug effects; D004247:DNA / Q000187:drug effects*; D004252:DNA Mutational Analysis; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced*
D004247:DNA; D015073:2-Acetylaminofluorene
2-acetyloaminofluoren--modelowy mutagen i hepatokancerogen. Charakterystyka oddziaływań z DNA.