[The coupling of phosphoinositide metabolism sensitive to ACTH with the adenylate cyclase system in the synaptosomes].
The effect of cAMP on the phosphoinositide metabolism increased by the ACTH, was studied in the rat brain synaptosomes. The data obtained suggest that a coupling of the phosphoinositide metabolism and the adenylate cyclase system occurs under these conditions.
Pavlinova
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D015056:1-Methyl-3-isobutylxanthine / Q000494:pharmacology; D000262:Adenylyl Cyclases / Q000502:physiology*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D000242:Cyclic AMP / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D008297:Male; D010716:Phosphatidylinositols / Q000378:metabolism*; D051381:Rats; D015290:Second Messenger Systems / Q000187:drug effects / Q000502:physiology; D013574:Synaptosomes / Q000187:drug effects* / Q000378:metabolism
D010716:Phosphatidylinositols; D000324:Adrenocorticotropic Hormone; D000242:Cyclic AMP; D000262:Adenylyl Cyclases; D002118:Calcium; D015056:1-Methyl-3-isobutylxanthine
Sviaz' fosfoinozitidnogo obmena, chuvstvitel'nogo k AKTG, s adenilattsiklaznoĭ sistemoĭ v sinaptosomakh.