Transcriptional repression by methylation of CpG.
Methylated DNA in mammals is associated with transcriptional repression and nuclease resistant chromatin. In this review we discuss how these effects may be mediated by proteins that bind to methylated DNA.
Meehan
R
R
Institute of Cell and Molecular Biology, University of Edinburgh, UK.
Lewis
J
J
Cross
S
S
Nan
X
X
Jeppesen
P
P
Bird
A
A
D000818:Animals; D004247:DNA / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism; D015226:Dinucleoside Phosphates / Q000378:metabolism; D008745:Methylation; D051379:Mice; D012097:Repressor Proteins; D014158:Transcription, Genetic
D004268:DNA-Binding Proteins; D015226:Dinucleoside Phosphates; D012097:Repressor Proteins; D004247:DNA