Epstein-Barr virus in Hodgkin's disease from patients with human immunodeficiency virus infection.
The polymerase chain reaction (PCR) technique was used to detect the presence of Epstein-Barr virus (EBV) DNA sequences in Hodgkin's disease specimens from 10 patients who were also positive for the human immunodeficiency virus (HIV). Eight of 10 specimens were positive for EBV, compared to 23 of 57 Hodgkin's disease specimens from patients without HIV infection, suggesting a closer association between Epstein-Barr virus infection and Hodgkin's disease in patients with HIV infection than in the general population.
Moran
C A
CA
Department of Infectious, Armed Forces Institute of Pathology, Washington, DC 20306-6000.
Tuur
S
S
Angritt
P
P
Reid
A H
AH
O'Leary
T J
TJ
D000328:Adult; D001483:Base Sequence; D004279:DNA, Viral / Q000032:analysis / Q000235:genetics; D006678:HIV / Q000235:genetics / Q000302:isolation & purification; D015658:HIV Infections / Q000150:complications* / Q000235:genetics; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000302:isolation & purification*; D006689:Hodgkin Disease / Q000150:complications / Q000235:genetics / Q000382:microbiology*; D006801:Humans; D008198:Lymph Nodes / Q000382:microbiology / Q000473:pathology; D008214:Lymphocytes / Q000382:microbiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction
D004279:DNA, Viral