title: De-novo biosynthesis of chlorinated aromatics by the white-rot fungus Bjerkandera sp. BOS55. Formation of 3-chloro-anisaldehyde from glucose.
abstract: The white-rot fungus Bjerkandera sp. BOS55 produced de-novo several aromatic metabolites. Besides veratryl alcohol and veratraldehyde, compounds which are known to be involved in the ligninolytic system of several other white-rot fungi, other metabolites were formed. These included anisaldehyde, 3-chloro-anisaldehyde and a yet unknown compound containing two chlorine atoms. Additionally GC/MS analysis revealed the production of small amounts of anisyl alcohol and 3-chloro-anisyl alcohol. After 14 days, the extracellular fluid of Bjerkandera BOS55 contained 100 microM veratraldehyde and 50 microM 3-chloro-anisaldehyde. This is the first report of de-novo biosynthesis of simple chlorinated aromatic compounds by a white-rot fungus. Anisaldehyde and 3-chloro-anisaldehyde were also produced by Bjerkandera adusta but not by Phanerochaete chrysosporium.
authors.affiliation: Department of Food Science, Agricultural University Wageningen, The Netherlands.
authors.forename: E
authors.initials: E
authors.lastname: de Jong
authors.forename: J A
authors.initials: JA
authors.lastname: Field
authors.forename: J A
authors.initials: JA
authors.lastname: Dings
authors.forename: J B
authors.initials: JB
authors.lastname: Wijnberg
authors.forename: J A
authors.initials: JA
authors.lastname: de Bont
mesh_terms: D001487:Basidiomycota / Q000378:metabolism; D001547:Benzaldehydes / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D008401:Gas Chromatography-Mass Spectrometry; D005947:Glucose / Q000378:metabolism*; D011124:Polyporaceae / Q000378:metabolism*
chemical_list: D001547:Benzaldehydes; C080818:3-chloroanisaldehyde; C024896:4-anisaldehyde; D005947:Glucose