title: An electron microscopic and morphometric study on the GABA-immunoreactive terminals in the cuneate nucleus of the rat.
abstract: Immunogold labelling was used to identify GABA-immunoreactive (GABA-IR) terminals in the cuneate nucleus of the rat. About 30% of the terminals surveyed were GABA-IR. They were mostly small, although a few of medium size were encountered. The terminals contained either polymorphic or round synaptic vesicles; these occurred in an approximately 5:1 ratio. Most of these terminals formed symmetric synapses with dendrites of various sizes. The GABA-IR terminals also made synaptic contacts with somata of cuneate neurons and axon terminals of unknown origin. In addition, a few GABA-IR terminals forming asymmetric synapses were found in the cuneate neuropil. The possible functional significance of the synaptic organisation is discussed.
authors.affiliation: Department of Anatomy, College of Medicine, National Taiwan University, Taipei.
authors.forename: C Y
authors.initials: CY
authors.lastname: Wen
authors.forename: K N
authors.initials: KN
authors.lastname: Chen
authors.forename: J H
authors.initials: JH
authors.lastname: Lue
authors.forename: S A
authors.initials: SA
authors.lastname: Chan
authors.forename: J Y
authors.initials: JY
authors.lastname: Shieh
mesh_terms: D000818:Animals; D003712:Dendrites / Q000648:ultrastructure; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D008526:Medulla Oblongata / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009411:Nerve Endings / Q000737:chemistry / Q000648:ultrastructure*; D051381:Rats; D017208:Rats, Wistar; D013569:Synapses / Q000648:ultrastructure; D013572:Synaptic Vesicles / Q000648:ultrastructure; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
chemical_list: D005680:gamma-Aminobutyric Acid