Genetic localization of Hao-1, blind-sterile (bs), and Emv-13 on mouse chromosome 2.
The blind-sterile (bs) mutation in the mouse was localized on Chromosome 2 between Hao-1 and Emv-13. N2 progeny from a backcross between congenic female 129.AKR-bs Emv-13 mice and (129.AKR-bs/bs x Mus musculus molossinus) F1 male mice were typed by analysis of isozyme variants for Hao-1, visible inspection for bs, and restriction fragment length polymorphism for Emv-13 and Emv-15. Comparison between markers on mouse Chromosome 2 and corresponding markers on human chromosomes suggest that the human homolog of bs will be located on 20q11-q13.
Spence
S E
SE
ABL-Basic Research Program, NCI-Frederick Cancer Research and Development Center, Maryland 21702.
Gilbert
D J
DJ
Harris
B S
BS
Davisson
M T
MT
Copeland
N G
NG
Jenkins
N A
NA
D000429:Alcohol Oxidoreductases / Q000235:genetics; D000818:Animals; D001766:Blindness / Q000235:genetics; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D007248:Infertility, Male / Q000235:genetics; D009052:Leukemia Virus, Murine / Q000235:genetics; D008297:Male; D051379:Mice / Q000235:genetics*; D009154:Mutation
D000429:Alcohol Oxidoreductases; C021380:L-2-hydroxyacid oxidase