Changes in human plasma dopamine-beta-hydroxylase activity after ketamine and halothane anesthesia.
The intravenous administration of ketamine hydrochloride to fifteen patients undergoing surgery produced no change in circulating plasma dopamine-beta-hydroxylase (DBH), although it produced a significant increase both in systolic blood pressure (BP) and diastolic BP during anesthesia. Halothane anesthesia that depress BP also produced no change in plasma DBH activity.
Akbaş
L
L
Department of Pharmacology, Faculty of Medicine, Cumhuriyet University Sivas, Turkey.
Sarioglu
Y
Y
Aker
A
A
D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D002648:Child; D002675:Child, Preschool; D004299:Dopamine beta-Hydroxylase / Q000097:blood / Q000187:drug effects*; D006221:Halothane / Q000494:pharmacology*; D006801:Humans; D007223:Infant; D007649:Ketamine / Q000494:pharmacology*; D008875:Middle Aged
D007649:Ketamine; D004299:Dopamine beta-Hydroxylase; D006221:Halothane