[ELISA for detection of anti-filamin antibody in sera from patient with myasthenia gravis].
The activity of anti-filamin antibody was determined in sera from 128 patients with myasthenia gravis (MG) by enzyme-linked immunosorbent assay (ELISA). The positive rate was 77.34%. No correlation was observed between anti-F-ab and nAchRab and CAEab. The antibody-absorbtion test were positive. The result demonstrated that anti-F-ab may play some role in the pathology of MG. The clinical use of ELISA for detection of anti-F-ab may help to diagnose MG.
Lin
H
H
Fuzhow General Hospital, Nanjin Command, PLA, Fujian.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000097:blood*; D002352:Carrier Proteins / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D003285:Contractile Proteins / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D064448:Filamins; D006801:Humans; D008297:Male; D008840:Microfilament Proteins / Q000276:immunology*; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000145:classification / Q000276:immunology*; D011950:Receptors, Cholinergic / Q000276:immunology
D001323:Autoantibodies; D002352:Carrier Proteins; D003285:Contractile Proteins; D064448:Filamins; D008840:Microfilament Proteins; D011950:Receptors, Cholinergic