An unusual cause of factitious mineralocorticoid excess.
The presence of hypokalaemia in hypertensive patient must prompt a search for increased mineralocorticoid activity. We describe and discuss the observation of a patient with biological markers of hypermineralocorticoidism, despite low plasma and urinary aldosterone levels, and suppressed plasma renin activity. This typical syndrome of apparent mineralocorticoid excess was secondary, in our patient, to prolonged administration of a mineralocorticoid-containing nasal spray.
Vanderijst
J F
JF
Département de Médecine Interne, Cliniques Universitaires St Luc, (U.C.L.), Bruxelles, Belgique.
Vandeleene
B
B
De Plaen
J F
JF
Kolanowski
J
J
D000471:Alkalosis / Q000139:chemically induced* / Q000150:complications; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005477:Fluprednisolone / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D006929:Hyperaldosteronism / Q000139:chemically induced; D007008:Hypokalemia / Q000139:chemically induced* / Q000150:complications; D008297:Male; D008875:Middle Aged; D014663:Nasal Decongestants / Q000009:adverse effects*; D012651:Self Medication
D014663:Nasal Decongestants; C065592:isoflupredone acetate; D005477:Fluprednisolone