[Skin graft protection by treatment of recipients with ultraviolet irradiated fragments of the donor spleen].
We have tested de possible protective effects of UVA radiated spleen fragments upon simultaneous skin allografts in 84 rats. Under these circumstances skin graft rejection was less evident with a 20 day graft disappearance rate of 46.87% rate in the treated series, that compares favourably with a 80% in the control series. This study shows a parallel increase in the mean survival time of skin grafts in treated specimens. The figures being 19.8 days in the treated series against 12.9 days in untreated controls. Spleen implants are finally shown to produce a healing stimulus in the skin graft zone. These differences are statistically significant.
Aznar Aznar
A
A
Centro de trabajo: Hospital Militar Gómez Ulla, Madrid.
Moratinos Palomero
P
P
Muro García
R
R
Llanes Menéndez
F
F
López Alonso
A
A
D000818:Animals; D002921:Cicatrix / Q000473:pathology; D006084:Graft Rejection / Q000517:prevention & control*; D006085:Graft Survival; D008297:Male; D011300:Preoperative Care / Q000379:methods*; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000473:pathology; D016038:Skin Transplantation; D013154:Spleen / Q000528:radiation effects* / Q000637:transplantation*; D014466:Ultraviolet Rays; D014945:Wound Healing
Protección de injertos de piel por tratamiento de los receptores con fragmentos de bazo del donante irradiados con ultravioleta.