[Estimation of hearing in patients with end stage renal failure being peritoneally dialyzed with and without furosemide in the dialysis fluid].
The purpose of our study was to estimate hearing state and effect of intraperitoneal administration of furosemide on an organ of hearing in the patients with end-stage renal failure being treated with intermittent peritoneal dialysis. Ten patients divided into two groups, were observed for three months. A weekly dosage of 1.2-2.0 g of furosemide was administered to the patients of first group while the patients of second group were not given furosemide. Based upon the studies, which had been carried out by pure tone audiometry method and Fowler's test and Belesy's audiometry, it was found the lesion of hearing, mainly in the range of higher frequency, having a character of cochlear hypoacusia. The further lesion of hearing was not seen within three months of regular treatment with intermittent peritoneal dialysis. The audiometric studies which had been carried out in different stages of treatment, did not show ototoxicity influence of furosemide added to dialysis fluid.
Korytowska
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Kliniki Laryngologii Katedry Chorób Uszu, Nosa, Gardła i Krtani AM im. K. Marcinkowskiego, Poznaniu.
Grzegorzewska
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D000328:Adult; D001301:Audiometry, Pure-Tone; D004334:Drug Administration Schedule; D005260:Female; D005665:Furosemide / Q000008:administration & dosage*; D006309:Hearing / Q000187:drug effects*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis
D005665:Furosemide
Ocena stanu słuchu u chorych na schyłkowa niewydolność nerek dializowanych otrzewnowo z dodatkiem i bez dodatku furosemidu do płynu dializujacego.