[Value (and limitations) of the RAST fx5 in pediatric allergological practice].
RAST f x 5 (CAP-system, Pharmacia), an in vitro assay testing a mixture of 6 food antigens, was systematically applied to 400 children and adolescents with respiratory pathologies possibly of allergic origin. The clinical aspects of the 293 test-negative patients were compared with those of the 107 positive cases. Furthermore, 84 positive sera were also evaluated against each of the 6 antigens regrouped in the f x 5. In this population with allergic respiratory diseases, the most frequently positive tests reacted with antigens of plant origins: wheat, peanut and soybean. From an economic point of view, first-line use of f x 5 markedly reduced the cost of a systematic study of food allergens, whose clinical justification remains to be demonstrated.
de Montis
G
G
Unité de Pathologie Respiratoire et d'Allergologie, Hôpital Saint-Vincent-de-Paul, Paris.
Georges
P
P
D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000097:blood; D005069:Evaluation Studies as Topic; D005260:Female; D005512:Food Hypersensitivity / Q000175:diagnosis*; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male; D011852:Radioallergosorbent Test; D012130:Respiratory Hypersensitivity / Q000097:blood / Q000209:etiology*
D007073:Immunoglobulin E
Intérêt (et limites) du RAST fx5 en pratique allergologique pédiatrique.