Progressive rubella panencephalitis. Follow-up EEG study of a case.
Progressive rubella panencephalitis is a very rare slow virus disease of the nervous system. The authors present a case, concerning a young man, aged 20 years, died 11 months after the onset of the disease. The following peculiarities of the case are emphasized: 1) the clinical symptomatology and the evolution (myoclonus, lack of cerebellar impairment) could suggest the diagnosis of SSPE; 2) the EEG recordings showed epileptiform abnormalities, long latency diffuse periodic complexes and--during interferon therapy and simultaneously with a temporary clinical improvement--the appearance of short latency anterior periodic complexes.
Guizzaro
A
A
1st School of Medicine, Chair of Neurophysiopathology, University of Naples.
Volpe
E
E
Lus
G
G
Bravaccio
F
F
Cotrufo
R
R
Paolozzi
C
C
D000328:Adult; D003937:Diagnosis, Differential; D004569:Electroencephalography; D004660:Encephalitis / Q000175:diagnosis / Q000382:microbiology* / Q000503:physiopathology / Q000523:psychology; D004827:Epilepsy / Q000382:microbiology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000382:microbiology; D012409:Rubella / Q000150:complications*; D013344:Subacute Sclerosing Panencephalitis / Q000175:diagnosis; D013997:Time Factors