[Cellular immunity indices in combined chronic exposure to stress and low concentrations of carbon monoxide (II). Experimental research].
Studies of the chronic combined effects of carbon monoxide low concentrations and psychoemotional stress revealed changes in the peripheral lymphocyte subpopulation in all groups of examinees, connected with the defense activation of the humoral immunity and functional decrease of T lymphocytes. Analysis of correlations of cell subpopulations revealed disorders of their relationships, augmenting with the intensity of exposure. Combined action of carbon monoxide in the maximal of studies concentrations with stress resulted in the most severe changes of nonspecific immunity, which proves decompensated decrease of immunity.
Dueva
L A
LA
Tolmachev
D A
DA
Volkova
A P
AP
D000818:Animals; D002248:Carbon Monoxide / Q000633:toxicity*; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D007111:Immunity, Cellular / Q000187:drug effects; D007113:Immunity, Innate / Q000187:drug effects; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D051381:Rats; D013315:Stress, Psychological / Q000276:immunology*
D002248:Carbon Monoxide
Pokazateli kletochnogo immuniteta pri sochetannom khronicheskom vozdeĭstvii stressa i malykh kontsentratsĭ oksida ugleroda (II). Eksperimental'noe issledovanie.