Computer simulation of erythrocyte transit in the cerebrocortical capillary network.
The relationship between erythrocyte flow path length and transit time was studied using a probabilistic computer simulation of erythrocyte transit in morphometrically reconstructed cerebrocortical microvascular network of the rat. The results suggest (1) a near-cubic relationship between erythrocyte flow and vessel diameter, (2) preferential pathways of erythrocyte flow, (3) an exponential relationship between erythrocyte transit time and flow path length.
Hudetz
A G
AG
Department of Physiology, Medical College of Wisconsin, Milwaukee.
D000818:Animals; D002196:Capillaries / Q000033:anatomy & histology / Q000502:physiology*; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000098:blood supply*; D002560:Cerebrovascular Circulation; D003198:Computer Simulation; D004912:Erythrocytes / Q000502:physiology*; D008433:Mathematics; D008953:Models, Anatomic; D008954:Models, Biological; D051381:Rats; D013314:Stress, Mechanical