[Regulation of the activity of neuron-specific enolase by certain endogenous compounds].
The effects of glycolysis metabolites and some amino acids on the activity of bovine brain enolase have been studied. The inhibiting effect of glycolysis metabolites, of which two (2-phosphoglycolate and glyceraldehyde 3-phosphate) may be functionally significant, has been demonstrated. The action mechanisms of these compounds within a range of physiological concentrations as well as the combined effect of glyceraldehyde 3-phosphate and phosphoglyceromutase on enolase activity have been investigated.
Nazarian
K B
KB
Vaĭs
M
M
Egorin
R U
RU
Kustzheba-Vuĭtsntska
I
I
Petkevich
Ia
Ia
D000596:Amino Acids / Q000502:physiology*; D000818:Animals; D001921:Brain / Q000201:enzymology; D002417:Cattle; D005986:Glyceraldehyde 3-Phosphate / Q000502:physiology; D006016:Glycolates / Q000378:metabolism; D006019:Glycolysis; D010751:Phosphopyruvate Hydratase / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
D000596:Amino Acids; D006016:Glycolates; D005986:Glyceraldehyde 3-Phosphate; D005680:gamma-Aminobutyric Acid; D010751:Phosphopyruvate Hydratase; C013193:phosphoglycolate
Reguliatsiia aktivnost neĭronspetsificheskoĭ enolazy nekotorymi éndogennymi soedineniiami.