title: [A study on the decomposition kinetics of vitamin C tablet].
abstract: Under the condition of relative humidity less than the critical relative humidity, the discoloration rate and decomposition rate of vitamin C tablet and the discoloration rate of vitamin C tablet in solution were studied at temperatures 60-90 degrees C and relative humidities 60%-80%. The general equation of the relationship between the apparent rate constant k, absolute temperature T and relative humidity RH is: k = k' exp(-E/RT) exp(mRH), where k' and m are constants, E is apparent activation energy. The values of k', m and E for discoloration, decomposition and discoloration in solution are different.
authors.affiliation: School of Pharmacy, West China University of Medical Sciences, Chengdu.
authors.forename: Y
authors.initials: Y
authors.lastname: Sun
authors.forename: B Z
authors.initials: BZ
authors.lastname: Ma
authors.forename: G K
authors.initials: GK
authors.lastname: Yin
mesh_terms: D001205:Ascorbic Acid / Q000737:chemistry*; D004355:Drug Stability; D006813:Humidity; D007700:Kinetics; D008433:Mathematics; D013696:Temperature
chemical_list: D001205:Ascorbic Acid