title: G-CSF mobilised progenitor cells in autologous transplantation: in vitro and in vivo aspects.
abstract: G-CSF administration leads to significant elevation in the levels of circulating progenitor cells. Infusion of these cells after high-dose chemotherapy is associated with accelerated platelet engraftment that has a considerable impact in shortening thrombocytopenia and reducing need for platelet transfusions.
authors.affiliation: The Royal Melbourne Hospital, Victoria, Australia.
authors.forename: C G
authors.initials: CG
authors.lastname: Begley
authors.forename: E
authors.initials: E
authors.lastname: DeLuca
authors.forename: P A
authors.initials: PA
authors.lastname: Rowlings
authors.forename: J
authors.initials: J
authors.lastname: Szer
authors.forename: D
authors.initials: D
authors.lastname: Watson
authors.forename: C
authors.initials: C
authors.lastname: Juttner
authors.forename: G
authors.initials: G
authors.lastname: Morstyn
authors.forename: R M
authors.initials: RM
authors.lastname: Fox
authors.forename: W
authors.initials: W
authors.lastname: Sheridan
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D016913:Blood Component Transfusion / Q000379:methods*; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006412:Hematopoietic Stem Cells / Q000187:drug effects*; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D013921:Thrombocytopenia / Q000188:drug therapy; D014182:Transplantation, Autologous
chemical_list: D000970:Antineoplastic Agents; D016179:Granulocyte Colony-Stimulating Factor