[The treatment results in the differential therapy of mouth carcinomas. A retrospective study of the patient population of the Oral Surgery Department (1978-1986) of the University of Göttingen].
In a retrospective observational study on malignomas of the oral and maxillofacial region a data material of 157 patients has been analyzed. Results of the therapy and the course of disease are presented. The average delay between the appearance of the first symptom respectively the beginning of a therapy and the treatment in a specialized department for maxillofacial surgery runs up to 4.3 month and 2.8 month respectively. This dissatisfying situation is corroborated by the results for TNM categories with more advanced tumors. Only 16.6% of the patients belong to the T1 category, 42% to the T2 category and 35.7% to the T3 category. In 30.5% of cases tumor cells are found in cervical lymph nodes. Correlations between the size and the localisation of the primary tumor and metastases are obviously. The results of treatment are presented in form of survival curves and curves for times of no recurrence. There is no advantage in a combination of chemotherapy and surgery instead of single surgical therapy. In cases of more advanced tumors in T2 and T3 category there is no recurrence after 2 years in 70% of surgical treatment and in 69% of combined surgical treatment and chemotherapy. The censored estimated survival rate after 5 years in cases of surgical treatment comes to 63%, in cases of combined therapy to 62%. The consistent radical neck dissection is of distinctive signification. Recurrencies in the neck dissection region appear in 8.2% of patients.
Reidick
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Abteilung Kieferchirurgie, Universität Göttingen.
Merten
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HA
Luhr
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D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000453:epidemiology / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D005860:Germany, West / Q000453:epidemiology; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000453:epidemiology / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000401:mortality; D009367:Neoplasm Staging; D012189:Retrospective Studies; D013503:Surgery Department, Hospital / Q000706:statistics & numerical data; D013515:Surgery, Oral
Behandlungsergebnisse unterschiedlich therapierter Mundhöhlencarcinome. Retrospektive Untersuchung aus dem Patientengut der Kieferchirurgischen Abteilung (1978-1986) der Universität Göttingen.