[Prevalence of heterozygosity for beta-thalassemia among intermediate lower school children in an area of the Venetian lacuna].
This paper reports the results of an epidemiologic survey carried out from 1987 to 1991 among intermediate school students in Chioggia (Venice, Italy) to detect beta-Thalassemia carriers. The screening tests (determination of Mean Corpuscular Volume, Hemoglobin A2) were performed in 3050/4055 (75%) students; the prevalence of carriers was of 3.1%. The results obtained identify this as a risk area for Thalassemia Major and suggest the necessity to adopt prevention measures such as medical information, population screening, genetic counseling and prenatal diagnosis.
Sarti
F
F
Clinica Medica I, Università di Padova, Italia.
Cesaro
S
S
Sanvitale
G
G
Tisato
A
A
Petris
M G
MG
Zanesco
L
L
D000293:Adolescent; D005260:Female; D006579:Heterozygote; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D017086:beta-Thalassemia / Q000453:epidemiology / Q000235:genetics*
Prevalenza dell'eterozigosi per la beta-talassemia fra gli studenti delle scuole medie inferiori in un'area della laguna veneta.