Plasma exchange therapy in pediatric patients. Plasma filtration with a unipuncture technique.
Therapeutic apheresis in children is limited by technical considerations, such as circuit blood volume, venous access and hemodynamic instability. Here we report our experience with 310 plasma-filtration sessions in 44 children (aged 9 months-17 years). We used a miniaturized circuit with a unipuncture technique and a "balancing system" which assured a permanent fluid equilibrium. This procedure is well adapted to children and always made pediatric plasma exchange therapy easier and safer. The more common indications remain Guillain-Barré syndrome and acute severe glomerular diseases.
Bouissou
F
F
Unité de Néphrologie Pédiatrique, CHU Purpan, Toulouse.
Remesy
M
M
Peyrille
F
F
Ghabril
R
R
Graber
D
D
Carrière
J P
JP
Barthe
P
P
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D010949:Plasma; D010951:Plasma Exchange / Q000379:methods*; D014462:Ultrafiltration / Q000379:methods*