[Primary necrosis of the corpus callosum (Marchiafava-Bignami's disease): report of 5 cases].
The clinicopathological study of five autopsied cases of Marchiafava-Bignami disease is reported. The demyelination of the central portion of the corpus callosum is the major characteristics of the disease. In two cases the demyelination also involved the anterior and posterior commissures. There is a clear relationship to alcoholism and malnutrition in the cases reported in the present study.
Falangola
M F
MF
Serviço de Anatomia Patológica (Setor de Neuropatologia), Hospital Universitário Prof. Edgard Santos (HUPES), Universidade Federal da Bahia, UFBa, Brasil.
De Queiroz
A C
AC
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications; D003337:Corpus Callosum / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D011502:Protein-Energy Malnutrition / Q000150:complications
Necrose primária do corpo caloso (doença de Marchiafava-Bignami). Relato de cinco casos.