title: Long-term oral ciprofloxacin in the treatment of prosthetic valve endocarditis due to Pseudomonas aeruginosa.
abstract: Prosthetic valve endocarditis caused by Pseudomonas aeruginosa is refractory to medical treatment alone and early valve replacement is necessary. We describe a 40-year-old patient in whom endocarditis developed in the early postoperative period, and reoperation was not considered feasible. Ciprofloxacin was administered orally in order to suppress bacteremia for 36 months. Long-term oral ciprofloxacin may provide an opportunity in the treatment of prosthetic valve endocarditis caused by Ps. aeruginosa in patients who are unfavorable candidates for reoperation.
authors.affiliation: Department of Medicine, Hacettepe University School of Medicine, Ankara, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Uzun
authors.forename: H E
authors.initials: HE
authors.lastname: Akalin
authors.forename: S
authors.initials: S
authors.lastname: Unal
authors.forename: M
authors.initials: M
authors.lastname: Demircin
authors.forename: A C
authors.initials: AC
authors.lastname: Yorgancioglu
authors.forename: B
authors.initials: B
authors.lastname: Ugurlu
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001021:Aortic Valve; D002939:Ciprofloxacin / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004697:Endocarditis, Bacterial / Q000188:drug therapy*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008943:Mitral Valve; D016459:Prosthesis-Related Infections / Q000188:drug therapy*; D011552:Pseudomonas Infections / Q000188:drug therapy*
chemical_list: D002939:Ciprofloxacin