[Effect of leukocyte depleting polyester filters on thrombocytapheresis concentrates].
We studied platelet loss, leukocyte depletion, T/B cell ratio, platelet morphology and platelet function (aggregation, hypotonic shock reaction, retention and retraction) prior to and after filtration through two different polyester filters (Sepacell PL-5A, Pall PL100) as well as the posttransfusional platelet increment 1 h after transfusion in 8 pairs of single-donor platelet concentrates (Cobe Spectra, Fresenius AS 104). Leukocyte depletion was effective (>99.9%) and platelet loss acceptable in both filters, all tests showing no indication of a diminished platelet function by filtration.
Weisbach
V
V
Abteilung Innere Medizin, Universitätsklinikum Rudolf Virchow, Freie Universität Berlin, BRD.
Riess
H
H
Gindi
N
N
Serke
S
S
Zeiler
T
T
Riewald
M
M
Zingsem
J
J
Eckstein
R
R
D016913:Blood Component Transfusion / Q000295:instrumentation; D001793:Blood Preservation / Q000295:instrumentation; D006801:Humans; D007958:Leukocyte Count; D008212:Lymphocyte Depletion / Q000295:instrumentation*; D016131:Lymphocyte Subsets / Q000166:cytology; D010976:Platelet Count; D010979:Platelet Function Tests; D010983:Plateletpheresis / Q000295:instrumentation*; D011091:Polyesters; D014462:Ultrafiltration / Q000295:instrumentation*
D011091:Polyesters
Der Einfluss leukozytendepletierender Polyesterfilter auf Thrombozytapheresekonzentrate.