Increased interleukin-6 activity in cardiac myxoma with mediastinal lymphadenopathy.
We report a case of cardiac myxoma with mediastinal lymphadenopathy which seems to be a very rare feature. Laboratory examination revealed high level of interleukin-6 (IL-6) activity in serum. Interestingly, after removal of cardiac myxoma, mediastinal lymphadenopathy disappeared on the chest CT and the level of serum IL-6 was decreased. These findings suggest that IL-6 which was probably derived from myxoma, may have played an important role in the development of lymphadenopathy.
Kuroki
S
S
Department of Internal Medicine, Saga Medical School, Japan.
Naitoh
K
K
Katoh
O
O
Yamada
H
H
Itoh
T
T
D005260:Female; D006338:Heart Neoplasms / Q000150:complications / Q000378:metabolism* / Q000601:surgery; D006801:Humans; D015850:Interleukin-6 / Q000096:biosynthesis*; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000209:etiology*; D008477:Mediastinal Diseases / Q000209:etiology*; D008875:Middle Aged; D009232:Myxoma / Q000150:complications / Q000378:metabolism* / Q000601:surgery; D014057:Tomography, X-Ray Computed
D015850:Interleukin-6