[Etoposide and cisplatin combination chemotherapy in a patient with small cell lung carcinoma under artificial hemodialysis].
A 70-year-old man with small cell carcinoma of the lung who was under artificial hemodialysis, was treated by combined administration of etoposide and cisplatin. Fifty mg. of etoposide in combination with 35 mg. of cisplatin were infused before dialysis. Before one hour and during dialysis, plasma etoposide and platinum levels decreased rapidly. No severe side effect was observed after the administration of etoposide and cisplatin. In conclusion, it was considered that cisplatin and etoposide could be given to the patient with malignant tumor under artificial hemodialysis.
Ono
S
S
Department of Radiology, Miyazaki Medical College, Japan.
Miyazaki
T
T
Nishikawa
K
K
Watanabe
K
K
Hisanaga
S
S
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D002945:Cisplatin / Q000008:administration & dosage / Q000097:blood; D005047:Etoposide / Q000008:administration & dosage / Q000097:blood; D006801:Humans; D007262:Infusions, Intravenous; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D008175:Lung Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D006435:Renal Dialysis
D005047:Etoposide; D002945:Cisplatin