title: [Traveler's diarrhea in Turkey. Prospective randomized therapeutic comparison of charcoal versus tannin albuminate/ethacridine lactate].
abstract: In most cases traveler's diarrhea is a self-limiting disease not requiring professional assistance. As data on self-treatment are very limited, a prospective randomized trial was performed in 620 German tourists spending a two week-holiday in Turkey. 31.6% of these travelers developed diarrhea and 186 were assigned to two treatment groups, receiving either medical coal or a combination of tannalbuminate and ethacridinlactate (TA/EL). In the TA/EL group stool frequencies significantly earlier returned to normal and complaints of moderate to severe abdominal pain were recorded less frequently (50 vs. 82.2%) than in patients receiving charcoal preparations. Both medications were well tolerated and TA/EL appeared more efficient for self medication of uncomplicated traveler's diarrhea.
authors.affiliation: Klinik I für Innere Medizin, Universität zu Köln.
authors.forename: D J
authors.initials: DJ
authors.lastname: Ziegenhagen
authors.forename: R
authors.initials: R
authors.lastname: Raedsch
authors.forename: W
authors.initials: W
authors.lastname: Kruis
mesh_terms: D000328:Adult; D000418:Albumins / Q000008:administration & dosage*; D000930:Antidiarrheals / Q000008:administration & dosage*; D002606:Charcoal / Q000008:administration & dosage*; D003967:Diarrhea / Q000188:drug therapy*; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D004975:Ethacridine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D047348:Hydrolyzable Tannins; D008297:Male; D011446:Prospective Studies; D013634:Tannins / Q000008:administration & dosage*; D014195:Travel; D014421:Turkey
chemical_list: D000418:Albumins; D000930:Antidiarrheals; D004338:Drug Combinations; D047348:Hydrolyzable Tannins; D013634:Tannins; C061215:Tannacomp; D002606:Charcoal; D004975:Ethacridine
vernacular_title: Reisediarrhö in der Türkei. Prospektiv randomisierter Therapievergleich Kohle versus Tanninalbuminat/Ethacridinlactat.