[Association of hyperthyroidism and diabetes mellitus. Description of a case with partial recovery of pancreatic beta-islet function].
The coexistence of Graves' disease and insulin-dependent diabetes mellitus is well known among autoimmune polyglandular syndromes and sustained by common underlying immune pathogenic factors. Hyperthyroidism itself may lead to impaired glucose tolerance in subjects with intact beta-cell function through various not well clarified mechanisms and treatment of thyroid hyperfunction, on the other side, generally ameliorates the degree of metabolic control when diabetes is pre- and/or coexisting. We report a case of Graves' disease associated with diabetes mellitus, in which a partial recovery of insulin secretion is documented after euthyroidism was restored.
Pandolfi
C
C
I Divisione Medica, Ospedale Maggiore, Lodi, Milano.
Pellegrini
L
L
Sbalzarini
G
G
D001327:Autoimmune Diseases / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005947:Glucose / Q000378:metabolism; D006111:Graves Disease / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism; D006801:Humans; D007515:Islets of Langerhans / Q000378:metabolism*; D008875:Middle Aged
D005947:Glucose
Associazione di ipertiroidismo e diabete mellito. Descrizione di un caso con parziale ripristino della funzione pancreatica beta-insulare.