[Evaluation of chromo-endoscopy for diagnosis of histological repair of gastric ulcer].
The chromoendoscopic features of healed gastric ulcers were investigated by the methylene blue test. Histological repair of healed ulcers was graded as either Ul3 (incompletely healed) or Ul4 (completely healed). Endoscopically, the Ul4 scar was observed as a flat granular area without any depression, and sometimes associated with redness, the Ul3 scar was observed as a distinct depression in the surrounding normal mucosal surface, and usually associated with homogenous redness. Follow-up studies of patients with Ul4 and Ul3 lesions showed that recurrence was significantly rare in patients with the Ul4 lesion than in patients with the Ul3 lesions. These findings indicate that healing of gastric ulcers should be defined endoscopically as crater disappearance. At 8 weeks after treatment with omepral, most of the ulcers were healed, but judged a as Ul3 scar.
Tatsuta
M
M
Department of Gastrointestinal Oncology, Center for Adult Diseases, Osaka.
Iishi
H
H
Okuda
S
S
D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors; D005753:Gastric Mucosa / Q000473:pathology / Q000503:physiopathology; D005773:Gastroscopy / Q000379:methods*; D017506:H(+)-K(+)-Exchanging ATPase; D006801:Humans; D008297:Male; D008751:Methylene Blue; D008875:Middle Aged; D009853:Omeprazole / Q000494:pharmacology / Q000627:therapeutic use; D012038:Regeneration; D013276:Stomach Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*
D000251:Adenosine Triphosphatases; D017506:H(+)-K(+)-Exchanging ATPase; D009853:Omeprazole; D008751:Methylene Blue