title: What proportion of isotope injected does the child receive in dynamic renal scanning?
abstract: Because of significant difficulties encountered in the manipulation of data from 99Tcm-DTPA and 99Tcm-mercaptoacetyltriglycine (MAG3) renogram studies, it was decided to try to improve the percentage dose of radioisotope injected and thus the number of counts obtained by using a minimum dose volume of 1 ml for all injections. This resulted in an improvement in the percentage dose injected. However, difficulties were still encountered in the younger children. 18.7% of children aged less than 3 months, received less than 50% of the injected dose, showing little or no improvement using the newer method. The difficulty of injecting small babies seems the most obvious reason. During the interpretation of the findings in paediatric radioisotope studies, it is important to remember that not all children may have received an adequate percentage dose to constitute a reliably diagnostic study.
authors.affiliation: Department of Nuclear Medicine, Hospital for Sick Children, London, UK.
authors.forename: M A
authors.initials: MA
authors.lastname: O'Reilly
authors.forename: I
authors.initials: I
authors.lastname: Gordon
authors.forename: H
authors.initials: H
authors.lastname: Thomas
authors.forename: B
authors.initials: B
authors.lastname: MacDonald
mesh_terms: D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007267:Injections; D011866:Radioisotope Renography; D017263:Technetium Tc 99m Mertiatide / Q000008:administration & dosage / Q000493:pharmacokinetics*; D016284:Technetium Tc 99m Pentetate / Q000008:administration & dosage / Q000493:pharmacokinetics*
chemical_list: D017263:Technetium Tc 99m Mertiatide; D016284:Technetium Tc 99m Pentetate