A peptide family being re-united: the angiotensins coming in from the cold.
The renin-angiotensin-aldosterone system is now considered to be far more complex than previously thought when the vasoconstrictor and other physiological effects of the octapeptide angiotensin II in the circulating blood were emphasized. The reasons for this altered viewpoint, involving angiotensins other than the octapeptide in the regulation of blood pressure, water and electrolyte homeostasis, are briefly advanced and discussed.
Osborn
E C
EC
Department of Renal Medicine, Southmead Hospital, Westbury-on-Trym, Bristol.
Davenport
A
A
Goodship
A E
AE
Mackenzie
J C
JC
D000803:Angiotensin I / Q000494:pharmacology; D000804:Angiotensin II / Q000494:pharmacology; D000805:Angiotensin III / Q000494:pharmacology; D000809:Angiotensins / Q000494:pharmacology; D000818:Animals; D001794:Blood Pressure; D006706:Homeostasis; D007668:Kidney / Q000502:physiology; D012084:Renin-Angiotensin System / Q000502:physiology*
D000809:Angiotensins; D000804:Angiotensin II; D000805:Angiotensin III; D000803:Angiotensin I