[The effect of administration of beta-carotene in an oil solution on its blood serum level and antioxidant status of patients with duodenal ulcer and erosive gastritis].
Adequately good consumption of beta-carotene was observed in patients with duodenal ulcer and erosive gastritis after daily treatment with 18 mg of the carotinoid used as 0.1% oil solution: concentration of beta-carotene was increased approximately 3-fold in blood serum of these patients. Concentration of retinol was not increased in blood serum after treatment with beta-carotene, thus indicating that the drug treatment was not dangerous. Treatment with beta-carotene led to improvement in the state of the antioxidative system of these patients as resistance of erythrocytes to peroxide hydrolysis was increased while content of malonic dialdehyde was decreased in blood serum. The carotene treatment contributed to arresting pain syndrome in patients with ulcers, to cicatrization of ulcers and to disappearance of gastric mucosal membrane erosion.
Spirichev
V B
VB
Levachev
M M
MM
Rymarenko
T V
TV
Iakushina
L M
LM
Kharitonchik
L A
LA
L'vovich
N A
NA
Karagodina
Z V
ZV
Lupinovich
V L
VL
Loranskaia
T I
TI
Lebedeva
R P
RP
D000293:Adolescent; D000328:Adult; D000975:Antioxidants; D002338:Carotenoids / Q000008:administration & dosage* / Q000097:blood / Q000627:therapeutic use; D004042:Dietary Fats, Unsaturated; D004381:Duodenal Ulcer / Q000097:blood* / Q000188:drug therapy; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism; D005260:Female; D005756:Gastritis / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D014801:Vitamin A / Q000097:blood; D019207:beta Carotene
D000975:Antioxidants; D004042:Dietary Fats, Unsaturated; D019207:beta Carotene; D014801:Vitamin A; D002338:Carotenoids; D008315:Malondialdehyde
Vliianie prema maslianogo rastvora beta-karotina na ego uroven' v syvorotke krovi i antioksidantnyĭ status bol'nykh iazvoĭ dvenadtsatiperstnoĭ kishki i érozivnym gastritom.