title: Abbott HCV EIA 2nd generation: a new screening assay.
abstract: An enzyme immunoassay for the detection of antibodies against structural and nonstructural domains of the hepatitis C virus (EIA-2) was compared to a first generation test (EIA-1) that can only detect antibodies against one nonstructural antigen (c100). EIA-2 revealed elevated detection rates as assessed in high risk and patient populations as well as lower repeat reactive rates in volunteer blood donors. Research test systems proved an increase in apparent specificity.
authors.affiliation: Blood Transfusion Center, Munich, FRG.
authors.forename: W
authors.initials: W
authors.lastname: Weise
authors.forename: U
authors.initials: U
authors.lastname: Bäcker
authors.forename: S
authors.initials: S
authors.lastname: Seidl
authors.forename: H
authors.initials: H
authors.lastname: Flacke
authors.forename: D
authors.initials: D
authors.lastname: Sondag
authors.forename: H
authors.initials: H
authors.lastname: Pirenne
authors.forename: E
authors.initials: E
authors.lastname: Schroeter
authors.forename: H
authors.initials: H
authors.lastname: Troonen
authors.forename: C
authors.initials: C
authors.lastname: Broeksma
authors.forename: H
authors.initials: H
authors.lastname: Heyermann
mesh_terms: D001782:Blood Donors; D001803:Blood Transfusion; D003937:Diagnosis, Differential; D006508:Hepatitis Antibodies / Q000032:analysis*; D006526:Hepatitis C / Q000276:immunology / Q000517:prevention & control*; D018937:Hepatitis C Antibodies; D006525:Hepatitis, Viral, Human / Q000276:immunology / Q000517:prevention & control; D006801:Humans; D007124:Immunoenzyme Techniques; D008403:Mass Screening; D012307:Risk Factors
chemical_list: D006508:Hepatitis Antibodies; D018937:Hepatitis C Antibodies