Platelet apheresis with Vivacell BT798 DEA, haemonetics V-50 and PCS-Plus: preparation efficiency and product quality using identical donors.
Different platelet apheresis techniques were used for preparing platelet concentrates: the continuous flow method with Vivacell BT 798 DEA, the discontinuous flow method with V-50 of Haemonetics, and their plasmapheresis device PCS-Plus. 20 of our donors underwent all three procedures. All platelet separations led to suitable platelet concentrates of 3 x 10(11) platelets within less than 90 min. However, the contaminating leukocytes reached 2 x 10(8). Due to less intense citrate reactions and a shorter donation time the donor acceptance of the continuous flow method was higher as compared with the discontinuous flow method.
Richter
E
E
Institut für Transfusionsmedizin, Humboldt-Universität, Berlin.
Pawlow
I
I
Krause
K P
KP
Matthes
G
G
D000328:Adult; D001782:Blood Donors; D001810:Blood Volume / Q000502:physiology; D004867:Equipment Design; D006801:Humans; D008297:Male; D010976:Platelet Count; D010983:Plateletpheresis / Q000295:instrumentation*