title: Special issues in transfusion medicine.
abstract: This article reviews four controversial aspects of transfusion practices: the clinical circumstances, survival, and complications of massive transfusion; specific problems related to neonatal transfusion practices and the surgical support of the small child, including the appropriate age for red cells to be transfused, cytomegalovirus transmission, and the reduction in homologous donor exposures; the clinical presentation, incidence, and prevention of transfusion-associated graft-versus-host disease; and the biochemistry, function, genetics, and clinical indication for replacement therapy of antithrombin III.
authors.affiliation: Department of Pathology, University of Texas Health Science Center, San Antonio.
authors.forename: C R
authors.initials: CR
authors.lastname: Harrison
authors.forename: P R
authors.initials: PR
authors.lastname: Sawyer
mesh_terms: D000990:Antithrombin III / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000209:etiology; D002648:Child; D006086:Graft vs Host Disease / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007035:Hypothermia / Q000209:etiology; D007231:Infant, Newborn; D065227:Transfusion Reaction
chemical_list: D000990:Antithrombin III