[Rheologic studies before and after therapeutic cytapheresis and plasma exchange treatment].
Changes in rheological properties of human blood before and after platelet pheresis were measured in patients with myeloproliferative diseases as well as in a control group of platelet donors. Although the subjective feeling of the patients during measurement did improve, a better rheological situation could not be demonstrated by the rheological parameters used. A reduction of platelets does not influence the viscosity of whole blood or of plasma. On the other hand, the viscosities of whole blood and plasma differed significantly before and after plasma-pheresis in patients with monoclonal gammopathies. The control group comprised patients without hyperviscosity syndrome and did not show any change in rheological parameters.
Waxenberger
Y
Y
Abteilung für Transfusionsmedizin und Immunhämatologie, Kilinkum der Universität Würzburg, BRD.
Schäd
S
S
Gross
D
D
Ullrich
H
H
Hohe
R
R
Langer
R
R
Henrich
H
H
Weibecke
D
D
D001781:Blood Component Removal; D001809:Blood Viscosity / Q000502:physiology*; D004907:Erythrocyte Deformability / Q000502:physiology; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000097:blood / Q000628:therapy; D009196:Myeloproliferative Disorders / Q000097:blood / Q000628:therapy*; D010265:Paraproteinemias / Q000097:blood / Q000628:therapy*; D010951:Plasma Exchange; D010976:Platelet Count; D010983:Plateletpheresis
D005340:Fibrinogen
Rheologische Untersuchungen vor und nach therapeutischen Zytapheresen und Plasmaaustauschbehandlungen.