Malignant fibrous histiocytoma in the skull--case report.
A 45-year-old male presented with a large calvarial mass caused by a malignant fibrous histiocytoma arising primarily from the frontal bone and extending into the intracranial space. Magnetic resonance imaging revealed a well-demarcated, mottled enhanced bulky tumor with several low-signal separations. He underwent extensive tumor and bone removal, followed by radiation therapy. Histological examination showed pleomorphic spindle cells in a storiform pattern. The tissue stained positive for alpha-1-antitrypsin and alpha-1-antichymotrypsin by immunohistochemical techniques.
Hatashita
S
S
Juntendo University Urayasu Hospital, Chiba.
Tajima
A
A
Ueno
H
H
D005624:Frontal Bone / Q000000981:diagnostic imaging / Q000473:pathology; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012888:Skull Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology