title: Transcriptional repression by methylation of CpG.
abstract: Methylated DNA in mammals is associated with transcriptional repression and nuclease resistant chromatin. In this review we discuss how these effects may be mediated by proteins that bind to methylated DNA.
authors.affiliation: Institute of Cell and Molecular Biology, University of Edinburgh, UK.
authors.forename: R
authors.initials: R
authors.lastname: Meehan
authors.forename: J
authors.initials: J
authors.lastname: Lewis
authors.forename: S
authors.initials: S
authors.lastname: Cross
authors.forename: X
authors.initials: X
authors.lastname: Nan
authors.forename: P
authors.initials: P
authors.lastname: Jeppesen
authors.forename: A
authors.initials: A
authors.lastname: Bird
mesh_terms: D000818:Animals; D004247:DNA / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism; D015226:Dinucleoside Phosphates / Q000378:metabolism; D008745:Methylation; D051379:Mice; D012097:Repressor Proteins; D014158:Transcription, Genetic
chemical_list: D004268:DNA-Binding Proteins; D015226:Dinucleoside Phosphates; D012097:Repressor Proteins; D004247:DNA