[Tubo-ovarian transplantation in the treatment of sterility. Experimental research].
Microsurgical transposition of fallopian tube and ovary has the potential of being an efficient therapeutic treatment in patients with tubal sterility. The Authors present their experience of microsurgical adnexal transplantation in rabbit by two different techniques: the first procedure by microvascular anastomosis of the ovarian vessels, the second one without vascular pedicle. Function is evaluated at various time after grafting by: exploratory laparotomy on day 30 to establish whether circulation to the grafts was still maintained; macroscopic and microscopic examination of ovaries and fallopian tubes. The microvascular techniques prove highly reliable in terms of immediate vascular patency rate but it is disappointing that 50% of the autografts has failed with blocked vessels by day 30. Perhaps this is due to the difficult techniques in anastomosing the ovarian vessels of small caliber. In spite of these outcomes the vascularized autografts were viable and functional after transplantation in contrast with the non-vascularized tubo-ovarian grafts which all failed. This experience encourages to believe that the microsurgical technique could be employed for homograft transplantation in woman with extensive ovarian and tubal damages.
Formelli
G
G
I Clinica Ginecologica Ostetrica P. Sfameni Università degli Studi di Bologna.
Bondesan
A
A
Rinaldi
A M
AM
Finelli
C
C
Sani
G
G
D000714:Anastomosis, Surgical; D000818:Animals; D005187:Fallopian Tubes / Q000098:blood supply / Q000637:transplantation*; D005260:Female; D008866:Microsurgery; D010053:Ovary / Q000098:blood supply / Q000637:transplantation*; D011817:Rabbits; D013524:Surgical Flaps
Il trapianto tubo-ovarico nel trattamento della sterilita'. Ricerca sperimentale.