title: Role of pi form of glutathione S-transferase (GST-pi) in cancer: a minireview.
abstract: The pi class of the glutathione S-transferases is the most abundant of the human glutathione S-transferases family and is expressed almost in all tissues. However, the role of this protein is still poorly defined. It is suggested that this protein may serve as a marker for malignant transformation in some tissues. Additionally it seems that the phenomenon of tumour drug resistance may depend on the elevation of the glutathione S-transferase-pi. In this article we have attempted to review present knowledge concerning above problems.
authors.affiliation: Department of Biochemistry, National Research Institute of Mother and Child, Warszawa, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Gajewska
authors.forename: M
authors.initials: M
authors.lastname: Szczypka
mesh_terms: D005982:Glutathione Transferase / Q000502:physiology*; D006801:Humans; D007527:Isoenzymes / Q000502:physiology*; D009369:Neoplasms / Q000201:enzymology*; D009626:Terminology as Topic
chemical_list: D007527:Isoenzymes; D005982:Glutathione Transferase