title: [Immunomodulating properties of sera in normal pregnant women].
abstract: The purpose of this study was to analyze the immunosuppressive properties of sera of normal pregnant women. Effects of pregnancy sera on the proliferation of mitogen (PHA, Con A, PWM)-induced lymphocytes were examined in healthy primiparas. The sera of normal pregnant women inhibited the proliferation of PHA- and Con A- induced both autologous and allogenic lymphocytes (obtained from nonpregnant and pre-eclamptic women), while remaining neutral towards the proliferation of PWM- induced lymphocytes in comparison with fetal calf serum. The basic immunomodulatory activity of the sera in pregnant women was contained in the heat-stable fraction.
authors.affiliation: Katedry Połoznictwa i Ginekologii WAM, Lodzi.
authors.forename: A
authors.initials: A
authors.lastname: Malinowski
authors.forename: M
authors.initials: M
authors.lastname: Szpakowski
authors.forename: H
authors.initials: H
authors.lastname: Tchórzewski
authors.forename: K
authors.initials: K
authors.lastname: Zeman
authors.forename: T
authors.initials: T
authors.lastname: Kowalczyk
authors.forename: L
authors.initials: L
authors.lastname: Podciechowski
authors.forename: P
authors.initials: P
authors.lastname: Oszukowski
mesh_terms: D000328:Adult; D002455:Cell Division / Q000187:drug effects; D003208:Concanavalin A / Q000494:pharmacology; D005260:Female; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D008213:Lymphocyte Activation / Q000276:immunology; D008214:Lymphocytes / Q000187:drug effects; D008934:Mitogens / Q000494:pharmacology; D011247:Pregnancy / Q000097:blood / Q000276:immunology*; D012016:Reference Values
chemical_list: D008934:Mitogens; D003208:Concanavalin A
vernacular_title: Immunomodulacyjne właściwości surowic zdrowych kobiet ciezarnych.