Cleavage of DNA by viologen related compounds and their incorporation into oligodeoxyribonucleotides.
The DNA cleavage reaction by viologen and related compound such as 2,7-diazapyrenium salt was investigated. These viologen analogues were successfully incorporated into the oligothymidylate in the form of covalent bonding at the site of the phosphorous backbone through the linker arm.
Ikeda
H
H
Institute for Chemical Research, Kyoto University, Japan.
Tanaka
K
K
Fuji
K
K
D004247:DNA / Q000187:drug effects*; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*; D014755:Viologens / Q000737:chemistry / Q000494:pharmacology*
D009838:Oligodeoxyribonucleotides; D014755:Viologens; D004247:DNA