[The effect of peat preparation on the release of histamine from basophils of atopic bronchial asthma].
Antigen-induced basophil histamine releasing (BHR) is an in vitro model of the immediate-type allergic reaction. We studied the influence of immunologically active peat preparation (PTT). On BHR induced with specific antigen or Con A. The highest concentration of PTT enhanced, but lower concentrations decreased antigen-induced BHR. Surprisingly, similar effect was observed with placebo, suggestions that immunologically inactive components of both preparations may be responsible for the modulatory activity.
Kowalski
M L
ML
Kliniki Pneumonologii i Alergologii AM, Lodzi.
Kuźmińska
B
B
Rozniecki
J
J
D000328:Adult; D001249:Asthma / Q000188:drug therapy* / Q000276:immunology; D001491:Basophils / Q000187:drug effects*; D005260:Female; D006632:Histamine / Q000276:immunology*; D006801:Humans; D008297:Male
D006632:Histamine
Wpływ preparatu torfowego tołpy (PTT) na uwalnianie histaminy z bazofilów u chorych na astme oskrzelowa atopowa.