Spontaneous platelet aggregation in thalassemic children and adolescents.
Spontaneous platelet aggregation was studied in 51 children and adolescents, comprising 30 nonsplenectomized thalassemic patients, 12 splenectomized thalassemic patients and 9 normal children. Spontaneous platelet aggregation was significantly increased in whole blood and platelet-rich plasma of splenectomized thalassemic patients but not in nonsplenectomized cases.
Laosombat
V
V
Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand 90112.
Wongchanchailert
M
M
Kenpitak
K
K
Wisitpongpon
C
C
D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D001791:Blood Platelet Disorders / Q000097:blood* / Q000453:epidemiology / Q000209:etiology; D002648:Child; D005260:Female; D006400:Hematocrit; D006446:Hemoglobin E; D006453:Hemoglobinopathies / Q000150:complications* / Q000601:surgery; D006454:Hemoglobins / Q000032:analysis; D006785:Hospitals, University; D006801:Humans; D015994:Incidence; D008297:Male; D010974:Platelet Aggregation; D010976:Platelet Count; D011183:Postoperative Complications / Q000097:blood* / Q000453:epidemiology / Q000209:etiology; D013156:Splenectomy / Q000009:adverse effects*; D013785:Thailand / Q000453:epidemiology; D017085:alpha-Thalassemia / Q000150:complications* / Q000601:surgery; D017086:beta-Thalassemia / Q000150:complications* / Q000601:surgery
D006454:Hemoglobins; D006446:Hemoglobin E