title: [The hypolipidemic action of water-soluble enterosorbents of cholesterol and bile acids in an experiment].
abstract: Experiments on rats, guinea pigs and rabbits with experimental dyslipoproteinemia have revealed that the new water-soluble high-molecular weight polymers containing digitonin (ED) or a quaternary nitrogen atom (EA) have a more marked hypolipidemic action than cholestyramine and normalize lipoprotein metabolism. The digitonin-containing enterosorbent has been shown to decrease the absorption of 4-14C-cholesterol, while the nitrogen-containing enterosorbent diminishes the absorption of 3H-cholic acid.
authors.forename: A M
authors.initials: AM
authors.lastname: Chistiakova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Frolova
authors.forename: V F
authors.initials: VF
authors.lastname: Triufanov
authors.forename: L E
authors.initials: LE
authors.lastname: Vasil'eva
authors.forename: V T
authors.initials: VT
authors.lastname: Lozovskiĭ
authors.forename: V E
authors.initials: VE
authors.lastname: Ryzhenkov
mesh_terms: D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism*; D002784:Cholesterol / Q000378:metabolism*; D002791:Cholesterol, Dietary / Q000008:administration & dosage; D004072:Digitonin / Q000627:therapeutic use; D016061:Enterosorption / Q000379:methods*; D005069:Evaluation Studies as Topic; D006168:Guinea Pigs; D006937:Hypercholesterolemia / Q000209:etiology / Q000378:metabolism / Q000628:therapy; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D008970:Molecular Weight; D009584:Nitrogen / Q000627:therapeutic use; D011108:Polymers / Q000627:therapeutic use; D011817:Rabbits; D051381:Rats; D012995:Solubility
chemical_list: D001647:Bile Acids and Salts; D002791:Cholesterol, Dietary; D000960:Hypolipidemic Agents; D011108:Polymers; D002784:Cholesterol; D004072:Digitonin; D009584:Nitrogen
vernacular_title: Gipolipidemicheskoe deĭstvie vodorastvorimykh énterosorbentov kholesterina i zhelchnykh kislot v éksperimente.