[An unusual chronic microvasculitis: Goodpasture's syndrome with late myocardial involvement].
We describe a disease, started in a female young adult patient as an apparent pulmonary siderosis, followed nine years later by an extracapillary proliferative nephritis, which developed to uremia in a few months. Later an intra-myocardial vasculitis, responsible of heart failure, appeared. Immune-histochemistry and serological tests exclude a disease mediated by anti-GMB antibodies, and pathologic features suggest a vasculitis mainly affecting lungs and kidneys.
Mori
R
R
Istituto di Clinica medica, Università Cattolica del Sacro Cuore, Roma.
Corvaglia
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AG
Frustaci
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A
D000328:Adult; D019867:Anti-Glomerular Basement Membrane Disease / Q000150:complications* / Q000175:diagnosis; D009202:Cardiomyopathies / Q000175:diagnosis / Q000209:etiology; D003331:Coronary Vessels; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006801:Humans; D009393:Nephritis / Q000209:etiology; D014511:Uremia / Q000209:etiology; D014657:Vasculitis / Q000175:diagnosis / Q000209:etiology*
Una insolita microangioite a decorso protratto: sindrome di Goodpasture estesa successivamente al miocardio.