[Cetirizine for treating allergic seasonal rhinitis].
In 14 persons suffering from allergic, seasonal rhinitis the efficacy of 14-days treatment of cetirizine (Zyrtec 10 mg/day) was evaluated. The study was performed in double blind randomised method. Cetirizine was significantly more effective than placebo in reducing the clinical symptoms of rhinitis near in 60% patients. The improvement of nasal mucosa state in laryngological investigation was observed in patients who were better clinically. The inhalatory challenge test with histamine in 9 patients was positive and after cetirizine treatment the bronchial hyperreactivity disappeared.
Grzelewska-Rzymowska
I
I
Kliniki Pneumonologii i Alergologii IMW AM, Lodzi.
Kalinowska-Graczyk
M
M
Kopczyński
J
J
Rozniecki
J
J
D000293:Adolescent; D000328:Adult; D001985:Bronchial Provocation Tests; D017332:Cetirizine / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009297:Nasal Mucosa / Q000187:drug effects; D006255:Rhinitis, Allergic, Seasonal / Q000175:diagnosis / Q000188:drug therapy*
D017332:Cetirizine
Cetyryzyna w leczeniu alergicznego sezonowego niezytu nosa.