title: Effect of cardiac or heart-lung transplantation on the quality of life of the paediatric patient.
abstract: Despite the increase in the use of heart and heart-lung transplantation as methods of treatment for children with end stage heart or lung disease, there is little documented research about the psychological implications of such procedures or about the effects of transplantation on quality of life. Twenty-eight children were studied before and 3 months after heart or heart-lung transplantation and compared with 28 normal children. Developmental and cognitive function were within the normal range, although performance was at a significantly lower level on a number of parameters compared with the normal group. There were no significant changes in any of the developmental or cognitive parameters after transplantation. Pre-operatively the prevalence of problem behaviour at home was significantly higher in the transplant group compared with the normal group, but there was a significant reduction in the prevalence of problem behaviour following transplantation. Early postoperative findings indicate an improvement in quality of life after heart or heart-lung transplantation but longer term follow-up is now necessary.
authors.affiliation: Cardiothoracic Unit, Harefield Hospital, Middlesex, UK.
authors.forename: J
authors.initials: J
authors.lastname: Wray
authors.forename: R
authors.initials: R
authors.lastname: Radley-Smith
authors.forename: M
authors.initials: M
authors.lastname: Yacoub
mesh_terms: D000293:Adolescent; D002648:Child; D002653:Child Behavior Disorders / Q000453:epidemiology* / Q000209:etiology; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D016027:Heart Transplantation / Q000009:adverse effects / Q000523:psychology*; D016041:Heart-Lung Transplantation / Q000009:adverse effects / Q000523:psychology*; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D011788:Quality of Life; D012649:Self Concept; D006113:United Kingdom