title: [Toxoplasmic retinochoroiditis].
abstract: Retinochoroiditis is a frequent ocular lesion in toxoplasmosis. It may be severe, and even lead to blindness. Sixteen cases of toxoplasmic retinochoroiditis verified through IFA were presented in this paper. Among these cases, 1 was of the multifocal type, its appearance being similar to that of the Coats disease; while the other 15 were of the focal type resembling to the central exudative retinitis (Rieger disease) or retinochoroidal scar. Serological finding of all the cases showed a positive IFA titer of > 1:80. A combination of pyrimethamine and sulfadiazine as well as spiramycin in addition to dexamethasone had been administered and proved effective. Since toxoplasmosis mostly occurs as latent and examination of the eye cannot differentiate from other causes of retinochoroiditis, so such clinical report of toxoplasmic retinochoroiditis was rare with particular reference in our country. The authors claimed that any individual presenting with retinochoroiditis suspected of toxoplasmosis should be subjected to serologic antibody test for establishing diagnosis.
authors.affiliation: Department of Ophthalmology, Ruijin Hospital, Shanghai Second Medical University.
authors.forename: M H
authors.initials: MH
authors.lastname: Zhang
authors.forename: H Z
authors.initials: HZ
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002825:Chorioretinitis / Q000188:drug therapy / Q000469:parasitology*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011739:Pyrimethamine / Q000008:administration & dosage; D013411:Sulfadiazine / Q000008:administration & dosage; D014126:Toxoplasmosis, Ocular / Q000188:drug therapy
chemical_list: D013411:Sulfadiazine; D011739:Pyrimethamine