[Quantitative assay of CD8+ (cytotoxic and suppressor) lymphocytes in patients with both asymptomatic and symptomatic HIV infection].
Lymphocytes CD8+ have been assayed prospectively in 245 individuals infected with HIV. Percentage and number of CD8+ have been nearly two-fold higher in asymptomatic patients or patients with lymphadenopathy than those in the control group. The number of CD8+ lymphocytes has been rapidly decreasing parallel to the progression of HIV (ARC and AIDS), while their percentage has increased--however insignificantly. There has been a positive correlation between the number of CD4+ and CD8+ cells and all clinical stages of HIV infection.
Radkowski
M
M
Zakładu Immunopatologii, Kliniki Nabytych Niedoborów Immunologicznych Instytutu Chorób Zakaźnych i Pasozytniczych, Warszawie.
Laskus
T
T
Kopicz-Kamińska
E
E
Babiuch
L
L
Slusarczyk
J
J
D000293:Adolescent; D000328:Adult; D016516:CD4-CD8 Ratio; D005260:Female; D015658:HIV Infections / Q000276:immunology*; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
Badania ilościowe limfocytów CD8+ (cytotoksycznych i supresorowych) u chorych z bezobjawowym i objawowym zakazeniem HIV.