Correlation of bacteriological flora of the urethra, glans and perineum with organisms causing urinary tract infection in the spinal injured male patient.
Positive urine cultures are common and often asymptomatic in the male spinal injured patient performing self clean intermittent catheterisation. It is possible that the positive urine cultures result from contamination from the colonised urethra at the time of catheterisation. This contamination could result in true infection of the bladder urine or yield false positive results, explaining the frequently seen asymptomatic cases. In a prospective study positive urine cultures were found on 58 occasions (74%) in 10 asymptomatic patients studied. In 19% of screenings, with positive urine cultures, an identical organism was cultured from the catheter specimen of urine, the perineum and the urethra. The flora of the anterior urethra is strongly correlated to that of the perineum (37.1%), as well as that of the bladder (52.6%). In 4 patients a correlation also existed between the urethra and fingers, and the perineum and fingers. This was associated with an increased incidence of positive urine culture in these patients. Suprapubic aspirates of urine before and after catheterisation cultured the same organisms. However, quantitative culture revealed colony counts that approached a 10-fold increase following catheterisation in one patient. This suggests that catheterisation is at least partially responsible for ascending infection in this group of patients. Catheter specimens were found to be a good representation of the bladder urine, with an 87.5% correlation.
Barnes
D G
DG
Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, England.
Timoney
A G
AG
Moulas
G
G
Shaw
P J
PJ
Sanderson
P J
PJ
D000328:Adult; D006801:Humans; D008297:Male; D010413:Penis / Q000382:microbiology*; D010502:Perineum / Q000382:microbiology*; D013119:Spinal Cord Injuries / Q000150:complications*; D014521:Urethra / Q000382:microbiology*; D014546:Urinary Catheterization; D014552:Urinary Tract Infections / Q000150:complications / Q000382:microbiology*