title: [The mechanisms of the formation of cardiogenic afferent effects after the development of local immune damage to the heart].
abstract: Sensitivity of cardiac receptors to several substances after local immune heart damage and the nature of cardiogenic influences on the circulation were studied in acute experiments o anesthetized dogs. The depressor reflexes from the heart were shown to disappear during 30 min. after immune heart damage, and vagal afferent impulse activity decreased. After immune heart damage, cardiac sympathetic afferent fibres were more sensitive to endogenous biological substances than to vagal ones. The sympathetic cardiac afferent system is found to be more sensitive to chemical agents, which is a decisive factor in formation of cardiogenic influences on the circulation during pathological processes in the heart.
authors.forename: V B
authors.initials: VB
authors.lastname: Pavliuchenko
authors.forename: O O
authors.initials: OO
authors.lastname: Moĭbenko
authors.forename: V V
authors.initials: VV
authors.lastname: Lysypenko
mesh_terms: D000344:Afferent Pathways / Q000187:drug effects / Q000503:physiopathology; D000818:Animals; D016718:Arachidonic Acid / Q000494:pharmacology; D001920:Bradykinin / Q000494:pharmacology; D009202:Cardiomyopathies / Q000209:etiology / Q000503:physiopathology*; D004285:Dogs; D004837:Epinephrine / Q000494:pharmacology; D006321:Heart / Q000187:drug effects / Q000294:innervation* / Q000503:physiopathology*; D007106:Immune Sera / Q000494:pharmacology; D007154:Immune System Diseases / Q000209:etiology / Q000503:physiopathology*; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D009206:Myocardium / Q000276:immunology; D013564:Sympathetic Nervous System / Q000187:drug effects / Q000503:physiopathology; D014630:Vagus Nerve / Q000187:drug effects / Q000503:physiopathology
chemical_list: D007106:Immune Sera; D016718:Arachidonic Acid; D001920:Bradykinin; D004837:Epinephrine
vernacular_title: Deiaki mekhanizmy formuvannia kardiohennykh aferentnykh vplyviv pislia rozvytku lokal'noho imunnoho poshkodzhennia sertsia.