title: [The effects of nitrendipine on the quality of life in the elderly patients with isolated systolic hypertension (ISH)].
abstract: By case-control study, we investigated the effects of nitrendipine on the quality of life in 100 patients who were participating in Chinese Trial of randomized double-blind systolic hypertension in the elderly. The results showed that the patients group had lower scores of quality of life than the matched normotensives (P < 0.05-P < 0.01). After 40-week treatment period, the active treatment group (45 patients) had satisfied blood-pressure control and improved physical symptoms. As compared with the active group, however, the control group (42 patients) scored significantly higher on physical symptoms (P < 0.05-P < 0.01), fewer on memory, vatality, vision, well-being and social activity (P < 0.05-P < 0.01). Our findings show that nitrendipine had some positive effects on the quality of life in the elderly patients with isolated systolic hypertension (ISH) and these can be meaningfully assessed with available psychosocial measures.
authors.affiliation: First Affiliated Hospital, Hunan Medical University, Changsha.
authors.forename: T
authors.initials: T
authors.lastname: Cai
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009568:Nitrendipine / Q000627:therapeutic use*; D011788:Quality of Life; D013599:Systole
chemical_list: D009568:Nitrendipine