Acquired bisalbuminemia in staphylococcal endocarditis treated with dicloxacillin.
An albumin fraction with increased anodal mobility was observed on cellulose acetate electrophoresis, isoelectric focusing, and immunoelectrophoresis of serum obtained 1 month after a 68-year-old male patient had been treated with dicloxacillin for Staphylococcus epidermidis endocarditis. The patient also suffered from rheumatoid arthritis demanding hospital treatment. Normal albumin results from several earlier runs were thus available, and follow-up showed reversion to normal albumin mobility. Treating albumin with dicloxacillin in vitro produced a corresponding mobility increase.
Winter
V
V
Rheumatism Foundation Hospital, Heinola, Finland.
Rosenvall
A
A
Heikkilä
S
S
von Essen
R
R
D000368:Aged; D001797:Blood Protein Electrophoresis; D004009:Dicloxacillin / Q000009:adverse effects* / Q000627:therapeutic use; D004588:Electrophoresis, Cellulose Acetate; D004697:Endocarditis, Bacterial / Q000188:drug therapy*; D006801:Humans; D007122:Immunoelectrophoresis; D007525:Isoelectric Focusing; D008297:Male; D012709:Serum Albumin / Q000187:drug effects* / Q000378:metabolism; D013203:Staphylococcal Infections / Q000188:drug therapy*; D013212:Staphylococcus epidermidis
D012709:Serum Albumin; D004009:Dicloxacillin