Flow cytometric analysis of T cell response in mice infected with Cowdria ruminantium.
A 3-fold increase in the numbers of Lyt-2+ T cells in the circulating blood of mice infected and re-infected with the Welgevonden stock of Cowdria ruminantium, as determined by flow cytometry, is supportive evidence that immunity in heartwater is cell-mediated. The rise in Lyt-2+ cells only after re-infection of the mice is further evidence that the development of immunity in heartwater is dependent on the unhindered and adequate replication of C. ruminantium.
Du Plessis
J L
JL
Onderstepoort Veterinary Institute.
Gray
C
C
Van Strijp
M F
MF
D000818:Animals; D000950:Antigens, Ly / Q000032:analysis; D016995:Ehrlichia ruminantium / Q000276:immunology*; D005260:Female; D005434:Flow Cytometry; D006357:Heartwater Disease / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D013601:T-Lymphocytes / Q000276:immunology*
D000950:Antigens, Ly