title: Aetiology of status epilepticus in Ibadan: a neuropathologic study.
abstract: In this neuropathologic study of 41 cases diagnosed as status epilepticus (SE) over a 10-year period at the University College Hospital, Ibadan (UCH), we found that the commonest cause was infection of the central nervous system (17 cases). The other aetiologic factors were: metabolic derrangement/toxic (14 cases) and cerebrovascular disease which was the most frequent cause in subjects above 12 years of age. It was encountered in 6 cases. Space occupying lesions which involved the frontal lobes were found in 4 cases. The conditions associated with the disease at death were: cerebral oedema, pulmonary oedema; pulmonary consolidation and pulmonary embolism. Our findings highlight the importance of looking for treatable conditions in patients presenting with this grave condition in this environment.
authors.affiliation: Department of Medicine, University College Hospital, Ibadan, Nigeria.
authors.forename: A
authors.initials: A
authors.lastname: Ogunniyi
authors.forename: J O
authors.initials: JO
authors.lastname: Ogunniyi
authors.forename: O
authors.initials: O
authors.lastname: Bademosi
authors.forename: B O
authors.initials: BO
authors.lastname: Osuntokun
authors.forename: A O
authors.initials: AO
authors.lastname: Adeuja
mesh_terms: D000293:Adolescent; D000328:Adult; D001927:Brain Diseases / Q000150:complications / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology; D002493:Central Nervous System Diseases / Q000150:complications* / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000150:complications / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D016779:Malaria, Cerebral / Q000150:complications / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D012189:Retrospective Studies; D013226:Status Epilepticus / Q000209:etiology* / Q000401:mortality