Ibopamine as a valuable adjunct and substitute for dopamine in bridging therapy before heart transplantation.
Ibopamine is an active dopamine analogue leading to improved renal perfusion and afterload reduction in heart failure. This report describes casuistic experiences in patients with severe heart failure awaiting heart transplantation. All patients could be stabilized, intravenous catecholamines be discontinued, and diuretics be reduced. Six of seven patients could be successfully transplanted. No major side effects were noted. Thus ibopamine can be a suitable adjunct for patients with endstage heart failure.
Kleber
F X
FX
Krankenhaus München-Schwabing, Akademisches Lehrkrankenhaus der Ludwig-Maximilians-Universität, München, FRG.
Sabin
G V
GV
Thyroff-Friesinger
U
U
Cabell
B
B
Glogar
D
D
D000328:Adult; D002316:Cardiotonic Agents / Q000008:administration & dosage*; D003846:Deoxyepinephrine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004298:Dopamine / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery; D016027:Heart Transplantation / Q000502:physiology*; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy* / Q000503:physiopathology; D011300:Preoperative Care
D002316:Cardiotonic Agents; C023487:ibopamine; D003846:Deoxyepinephrine; D004298:Dopamine