title: [Results and experiences of transvenous endocardial defibrillator therapy].
abstract: We studied the follow-up of 72 patients who underwent implantation of a transvenous defibrillation lead system (ELS) (Endotak, CPI). All patients had ventricular tachycardia (VT) or fibrillation (VF) refractory to antiarrhythmic drug therapy. There were 51 patients with coronary disease and 21 patients had non-ischemic VT/VF. ELS was combined with a subcutaneous patch in 52 patients and implanted alone ("single lead only") in 20 patients. 40 patients received the ELS combined with antitachycardia pacing devices (Ventak PRx, CPI; Cadence, Ventritex) and 32 patients with the Ventak P 1600 or P2, CPI. Implantation of the ELS was attempted in 80 patients and performed in 72 patients (90%): Intraoperatively, the mean defibrillation threshold (DTF) was > 25 Joule (J) in five patients and no reliable ELS position was possible to achieve in three patients. These eight patients underwent thoracotomy with epicardial patch implantation. The mean DFT was < or = 20 J in all 72 patients with a mean DFT of 14 +/- 8 J in VT patients and 17 +/- 10 J in VF patients. Two of 80 patients (3%) died: one patient died intraoperatively and one during the mean follow-up of 6 +/- 2 (< 1 to 18) months. Complications occurred in three patients (4%): Dislocation of the Endotak electrode was observed in two patients (3%) and one patient developed pneumothorax postoperatively. Our data show that the ELS is most suitable in the majority of patients with VT/VF and is the approach of first choice for cardioverter defibrillator implantation at the present time. However, despite a relatively low intra- and perioperative complication rate, this approach should not be performed in institutions without cardiac surgery.
authors.affiliation: Abteilung Kardiologie, Medizinischen Hochschule Hannover.
authors.forename: H J
authors.initials: HJ
authors.lastname: Trappe
authors.forename: H G
authors.initials: HG
authors.lastname: Fieguth
authors.forename: O
authors.initials: O
authors.lastname: Weber-Conrad
authors.forename: W
authors.initials: W
authors.lastname: Schöhl
authors.forename: T
authors.initials: T
authors.lastname: Wahlers
authors.forename: B
authors.initials: B
authors.lastname: Kielblock
authors.forename: P
authors.initials: P
authors.lastname: Wenzlaff
authors.forename: H
authors.initials: H
authors.lastname: Klein
authors.forename: P R
authors.initials: PR
authors.lastname: Lichtlen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002036:Bundle of His / Q000503:physiopathology; D002304:Cardiac Pacing, Artificial; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015996:Survival Rate; D017180:Tachycardia, Ventricular / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D014693:Ventricular Fibrillation / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*
vernacular_title: Ergebnisse und Erfahrungen der transvenösen endokardialen Defibrillatortherapie.