title: Changes in ribosomal proteins during colony development in Streptomyces.
abstract: The structure and functionality of the ribosomal subunits of the substrate and the aerial mycelium of Streptomyces antibioticus were compared. Using SDS-PAGE and HPLC, several differences between the ribosomal protein pattern from both stages of development were observed, including a clear decrease in the L7/L12 content of the aerial mycelium. The activity of the aerial mycelia ribosomes was also decreased when compared with that of the substrate mycelium. This effect was more pronounced in the 50S subunit. These results suggest that during cell differentiation in Streptomyces important changes occur at the ribosomal level, particularly in the transition from the substrate to the aerial mycelium.
authors.affiliation: Departamento de Biologia Funcional, Universidad de Oviedo, Spain.
authors.forename: L M
authors.initials: LM
authors.lastname: Quirós
authors.forename: F
authors.initials: F
authors.lastname: Parra
authors.forename: J A
authors.initials: JA
authors.lastname: Salas
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D012269:Ribosomal Proteins / Q000378:metabolism*; D013171:Spores, Bacterial; D013302:Streptomyces / Q000254:growth & development / Q000378:metabolism* / Q000502:physiology
chemical_list: D001426:Bacterial Proteins; D012269:Ribosomal Proteins