title: Pathological rupture of malarial spleen.
abstract: Two cases of spontaneous rupture of malarial spleen are reported here. One of them was a male who was on chloroquine for an acute attack of malaria. While on therapy, he complained of pain in left hypochondrium followed by palpitations. The other patient was a female who was admitted for continuous dull aching pain and fever. In both the patients, exploratory laparotomy revealed an enlarged spleen with tear. Splenectomy was performed. Histopathological examination revealed dilated congested sinusoid with follicular atrophy, and RBCs with malarial parasites. The post-operative course was smooth in both patients.
authors.affiliation: Dept of Gastroenterological Surgical Services, TN Medical College, Bombay, Maharashtra.
authors.forename: A J
authors.initials: AJ
authors.lastname: Mokashi
authors.forename: R G
authors.initials: RG
authors.lastname: Shirahatti
authors.forename: S K
authors.initials: SK
authors.lastname: Prabhu
authors.forename: K R
authors.initials: KR
authors.lastname: Vagholkar
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D016780:Malaria, Vivax / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012422:Rupture, Spontaneous; D013156:Splenectomy; D013161:Splenic Rupture / Q000473:pathology* / Q000601:surgery