[Study of the pisum sativum agglutinin receptors and DNA ploidy during carcinogenesis in esophageal epithelium by flow cytometry].
The relative mean contents of pisum sativum agglutinin receptors and DNA of human normal esophageal epithelium, its atypical hyperplasia as well as esophageal carcinoma were determined respectively by flow cytometry. The results revealed that the relative mean contents of pisum sativum agglutinin receptors which denote membrane composition and DNA which denote nuclear composition were increased gradually from normal, dysplastic and then malignant esophageal tissues. This suggested that during the neoplastic transformation, changes of the cell membrane component may correlate with changes of the cell nuclear component.
Lu
L M
LM
Department of Experimental Pathology, Hebei Medical College, Shijiazhuang.
D000782:Aneuploidy; D002478:Cells, Cultured; D004247:DNA / Q000032:analysis / Q000235:genetics; D004273:DNA, Neoplasm / Q000032:analysis / Q000235:genetics*; D004171:Diploidy; D004847:Epithelial Cells; D004938:Esophageal Neoplasms / Q000235:genetics / Q000473:pathology*; D004947:Esophagus / Q000737:chemistry / Q000166:cytology*; D005434:Flow Cytometry; D006801:Humans; D006965:Hyperplasia; D037102:Lectins; D037121:Plant Lectins; D011975:Receptors, Mitogen / Q000032:analysis*; D014407:Tumor Cells, Cultured
D004273:DNA, Neoplasm; D037102:Lectins; D037121:Plant Lectins; D011975:Receptors, Mitogen; C036292:pea lectin; D004247:DNA