[Establishment of a bank of cryopreserved valve homografts and clinical use in ninety-two patients].
Good long-term results obtained with homologous valve grafts, specially for correction of congenital cardiac defects, prompted us to create a local cryopreserved homograft bank. A 5-year experience is described, including indications for harvesting, techniques of preparation, cryopreservation and thawing. During this period, 195 homografts entered the bank and 92 were used. Among these 92 clinical cases, 74 consisted of right ventricular outflow tract reconstruction (47 valved conduit and 27 monocusp bearing patch) and 17 were left ventricular outflow tract reconstructions (11 free hand aortic valve and 6 aortic root replacement). Only one case was a tricuspid replacement with a stented homograft. Short-term results, with these homografts, are satisfactory and are compared with long-term results reported in the literature. The authors insist on using very thorough techniques and constant quality control. New developments should include viability control and immunological studies.
Kreitmann
B
B
Service de Chirurgie Cardiaque, Hôpital d'Enfants, Groupe Hospitalier de la Timone, Marseille, France.
Riberi
A
A
Zeranska
M
M
Perez
R
R
Ladaique
P
P
Novakovitch
G
G
Metras
D
D
D001021:Aortic Valve; D015925:Cryopreservation / Q000379:methods*; D006330:Heart Defects, Congenital / Q000601:surgery; D016027:Heart Transplantation / Q000379:methods*; D006801:Humans; D011664:Pulmonary Valve; D014015:Tissue Banks; D014184:Transplantation, Homologous
Constitution d'une banque d'homogreffes valvulaires cryopréservées et utilisation clinique chez quatre-vingt-douze patients.