title: Bone histomorphometry in Cushing's syndrome.
abstract: Bone involvement is a common finding in Cushing's syndrome. The actions of corticosteroids on bone have been studied quite intensively but only a few studies of bone histomorphometry in this syndrome have been published. In this paper we present histomorphometric measurements of bone activity in 7 patients with a postoperative reevaluation in two. The results show irregular alterations on histomorphometric parameters with an increased bone resorption and decreased bone formation rate. After surgery the abnormalities changed towards normal.
authors.affiliation: Endocrine Service, 1st Medical Clinics Hospital das Clínicas, University of São Paulo, Brazil.
authors.forename: A
authors.initials: A
authors.lastname: Borelli
authors.forename: M O
authors.initials: MO
authors.lastname: Leite
authors.forename: P H
authors.initials: PH
authors.lastname: Correa
authors.forename: V
authors.initials: V
authors.lastname: Jorgetti
authors.forename: J A
authors.initials: JA
authors.lastname: Marcondes
authors.forename: J R
authors.initials: JR
authors.lastname: Batalha
authors.forename: A B
authors.initials: AB
authors.lastname: Cintra
authors.forename: B L
authors.initials: BL
authors.lastname: Wajchenberg
mesh_terms: D000328:Adult; D001862:Bone Resorption / Q000473:pathology; D001842:Bone and Bones / Q000473:pathology*; D002118:Calcium / Q000652:urine; D003480:Cushing Syndrome / Q000097:blood / Q000473:pathology* / Q000601:surgery; D005260:Female; D006728:Hormones / Q000097:blood / Q000652:urine; D006801:Humans; D007085:Ilium / Q000473:pathology
chemical_list: D006728:Hormones; D002118:Calcium