title: Plasma exchange therapy in pediatric patients. Plasma filtration with a unipuncture technique.
abstract: Therapeutic apheresis in children is limited by technical considerations, such as circuit blood volume, venous access and hemodynamic instability. Here we report our experience with 310 plasma-filtration sessions in 44 children (aged 9 months-17 years). We used a miniaturized circuit with a unipuncture technique and a "balancing system" which assured a permanent fluid equilibrium. This procedure is well adapted to children and always made pediatric plasma exchange therapy easier and safer. The more common indications remain Guillain-Barré syndrome and acute severe glomerular diseases.
authors.affiliation: Unité de Néphrologie Pédiatrique, CHU Purpan, Toulouse.
authors.forename: F
authors.initials: F
authors.lastname: Bouissou
authors.forename: M
authors.initials: M
authors.lastname: Remesy
authors.forename: F
authors.initials: F
authors.lastname: Peyrille
authors.forename: R
authors.initials: R
authors.lastname: Ghabril
authors.forename: D
authors.initials: D
authors.lastname: Graber
authors.forename: J P
authors.initials: JP
authors.lastname: Carrière
authors.forename: P
authors.initials: P
authors.lastname: Barthe
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D010949:Plasma; D010951:Plasma Exchange / Q000379:methods*; D014462:Ultrafiltration / Q000379:methods*