Prevention and treatment of osteoporosis. One of the most frequent disorders in American women: a review.
This review summarizes basic pathophysiology, epidemiology, classification and theories on the etiology of osteoporoses. Diagnostic, preventative and therapeutic aspects are discussed including the use of hormones and hormone analogues (estrogen, progestins, calcitonins, anabolic steroids), calcium, fluoride, bisphosphonates, vitamins D and their metabolites and the recently proposed "coherence therapy". Reference is made to new compounds under study including imidazoquinazolinones, methylxanthines and benzothiophenes.
Ambrus
J L
JL
State University of New York, Department of Internal Medicine, Buffalo.
Hoffman
M
M
Ambrus
C M
CM
Hreshchyshyn
M M
MM
Moore
D
D
Munschauer
F E
FE
D002116:Calcitonin / Q000627:therapeutic use; D002118:Calcium / Q000627:therapeutic use; D004967:Estrogens / Q000627:therapeutic use; D012968:Etidronic Acid / Q000627:therapeutic use; D005260:Female; D006801:Humans; D010024:Osteoporosis / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control*; D012969:Sodium Fluoride / Q000627:therapeutic use
D004967:Estrogens; D012969:Sodium Fluoride; D002116:Calcitonin; D012968:Etidronic Acid; D002118:Calcium