[The sensitivity of bacterial strains of Yersinia pestis isolated from voles to normal human serum].
The work deals with the results of the study of the viability of Y. pestis strains, isolated from voles in different natural foci of plague, in human normal serum (HNS) and its dependence on the assimilation of ions of exogenic iron. The cultures isolated at the Transcaucasian mountain focus of infection and having no small plasmid pYP were found highly sensitive to HNS. The introduction of the sources of iron, such as hemoglobin or ferritin, into the serum decreased its bactericidal effect.
Gvozdenko
N A
NA
Valentsev
V E
VE
Rublev
B D
BD
Ryzhkov
V Iu
VIu
D000818:Animals; D003411:Arvicolinae / Q000382:microbiology*; D001770:Blood Bactericidal Activity; D004197:Disease Reservoirs; D006801:Humans; D007106:Immune Sera / Q000494:pharmacology*; D007501:Iron / Q000097:blood; D008826:Microbial Sensitivity Tests; D010957:Plasmids; D012800:Siberia; D013696:Temperature; D015010:Yersinia pestis / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification
D007106:Immune Sera; D007501:Iron
Chuvstvitel'nost' shtammov bakteriĭ Yersinia pestis, vydeliaemykh ot polevok, k normal'noĭ syvorotke cheloveka.