[Biologically active substances from the skin that influence the proliferation and differentiation of cultured human keratinocytes].
Three fractions of biologically active substances of human skin varying in molecular weight (F1 > 15 kD, F2 1.4-15 kD, F3 < 1.4 kD) were tested in primary and regenerating cultures of human epidermal keratinocytes. F1 and F3 caused stimulation of keratinocyte proliferation, F2 inhibited proliferation and enhanced terminal differentiation of epidermal cells.
Lopukhin
Iu M
IuM
Arion
V Ia
VIa
Ivanova
V F
VF
Belova
O V
OV
Kapitanov
A B
AB
D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured / Q000166:cytology / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D006133:Growth Substances / Q000494:pharmacology*; D006801:Humans; D015603:Keratinocytes / Q000166:cytology / Q000187:drug effects*; D008970:Molecular Weight; D012879:Skin Physiological Phenomena
D006133:Growth Substances
Biologicheski aktivnye veshchestva kozhi, vliiaiushchie na proliferatsiiu i differentsirovku kul'tiviruemykh keratinotsitov cheloveka.