Changes in tissue histology associated with adaptation and acclimation to hypoxia.
Newborn kittens are adapted to hypoxia by having an oxygen department respiration rate. In part, this is due to the structure of the liver which results in a great reduction of oxygen consumption in this organ in response to hypoxia. Older animals possess an oxygen independent respiration rate which is not lost when they acclimate to hypoxia. Instead, there are histological changes which permit the liver to consume oxygen at the same rate as before by facilitating intracellular oxygen transport.
Longmuir
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Department of Biochemistry, North Carolina State University, Raleigh 27695-7622.
D000064:Acclimatization / Q000502:physiology; D000222:Adaptation, Physiological; D000818:Animals; D000831:Animals, Newborn; D002415:Cats; D000860:Hypoxia / Q000473:pathology / Q000503:physiopathology*; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism / Q000473:pathology; D051379:Mice; D010101:Oxygen Consumption / Q000502:physiology