title: A cluster of dispensable genes within the human cytomegalovirus genome short component: IRS1, US1 through US5, and the US6 family.
abstract: By insertional mutagenesis, human cytomegalovirus recombinants deleted of each of the US6 glycoprotein family genes were isolated. A recombinant lacking IRS1, US1 through US5, and most of the US6 family was also isolated. The growth kinetics of these mutants were similar to that of the wild type. A dispensable cluster of genes was identified.
authors.affiliation: Molecular Biology Section, American Cyanamid Co., Pearl River, New York 10965.
authors.forename: T R
authors.initials: TR
authors.lastname: Jones
authors.forename: V P
authors.initials: VP
authors.lastname: Muzithras
mesh_terms: D002478:Cells, Cultured; D003587:Cytomegalovirus / Q000235:genetics*; D005814:Genes, Viral; D006801:Humans; D005810:Multigene Family; D016254:Mutagenesis, Insertional; D009693:Nucleic Acid Hybridization; D015183:Restriction Mapping