title: [Neoadjuvant chemotherapy in combined treatment of breast cancer].
abstract: The paper deals with results of complex treatment of 387 patients with stage III breast cancer assigned to either neoadjuvant chemotherapy and preoperative radiotherapy or radiation alone. A study of immediate and end results showed combination of the two modalities to be more effective than each method alone in terms of degree of regression of primary tumor and, particularly, lymph node metastases and duration of recurrence-free period.
authors.forename: V F
authors.initials: VF
authors.lastname: Semiglazov
authors.forename: E E
authors.initials: EE
authors.lastname: Topuzov
authors.forename: Ia L
authors.initials: IaL
authors.lastname: Bavli
authors.forename: O A
authors.initials: OA
authors.lastname: Ivanova
authors.forename: I K
authors.initials: IK
authors.lastname: Seleznev
authors.forename: O M
authors.initials: OM
authors.lastname: Golubeva
authors.forename: A A
authors.initials: AA
authors.lastname: Orlov
authors.forename: O F
authors.initials: OF
authors.lastname: Chepik
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000401:mortality / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008207:Lymphatic Metastasis; D015409:Mastectomy, Radical; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D011300:Preoperative Care; D011446:Prospective Studies; D011879:Radiotherapy Dosage; D012074:Remission Induction; D013852:Thiotepa / Q000008:administration & dosage
chemical_list: D003520:Cyclophosphamide; D013852:Thiotepa; D005472:Fluorouracil; D008727:Methotrexate
vernacular_title: Neoad''iuvantnaia khimioterapiia v kompleksnom lechenii raka molochnoĭ zelezy.