A cytogenetic study of five rare karyotypes.
The results of chromosome analysis of 5 cases from our genetic counseling showed that among these patients, 4 had two or more repeated spontaneous abortions. Structural abnormalities with the karyotypes 46, XX, t(1;11)(q42;q13), 46, XY, t(17;19)(q21;p13.3), 46, XY, t(4;5)(p13;q35) were reported for the first time in the literature abroad. The karyotypes 46, XX, t(16;18)(q24;q21), 46,XX, t(3;8)(p21;q24.3) were reported for the first time in the literature at home. A discussion is made on the origin of chromosome aberration and the cause of repeated spontaneous abortions.
Yang
Z R
ZR
Department of Medical Genetics, Tongji Medical University, Wuhan.
Xiao
Y Z
YZ
Liu
X X
XX
D000026:Abortion, Habitual / Q000235:genetics*; D002869:Chromosome Aberrations; D005260:Female; D005836:Genitalia, Female / Q000002:abnormalities; D006801:Humans; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D014960:X Chromosome; D014998:Y Chromosome