[Observations on the long-term immune effect on healthy children of inoculating HB vaccine and the effect of a booster dose].
This article reported the results of inoculating HB vaccine made in China into healthy children of O-1-2-month programme, under sero-epidemiological observation for 5 years. They showed that the highest peak of immunization was reached in the sixth month and then gradually diminished with the lapse of time until the 5th year when 74.1% of the immunized still had > or = 10 mIU/ml. That meant a good protective effect. Time of keeping anti-HBs had a direct bearing on the value of the highest period. According to the statistics it was told that. It took 6 years and 8 months for anti-HBs to fall below 10 mIU/ml. In the fifth year a booster lose was given with good response. An elevation of 12.1 times the previous immunizing level was observed, showing that a booster dose after 5 years of first dose of immunization was appropriate.
Yuan
J D
JD
Sanitary and Anti-epidemic Station of Zhifu District Yantai Shandong.
D002648:Child; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000097:blood*; D017325:Hepatitis B Vaccines / Q000276:immunology*; D006801:Humans; D007117:Immunization, Secondary; D008297:Male; D016036:Seroepidemiologic Studies; D013997:Time Factors
D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines