Thymus lipids in continuously irradiated rats.
Male Wistar rats were irradiated continuously with a daily dose of 0.19 Gy (120 days), 0.57 Gy (90 days) and 0.96 Gy (35 days) of gamma rays. An other group of rats was irradiated continuously with graded doses of gamma rays, up to total exposures ranging from 3.83-19.15 Gy. Depending on both the daily dose and total exposure, there was a decrease in phospholipid content in the thymus which correlated well with thymus weight changes. The decrease in triacylglycerol content was a less reliable sign of radiation damage. The phospholipid content reflecting the patterns of organ cellularity is a valuable indicator of the extent as well as recovery from radiation-induced injury to the thymus.
Ahlers
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I
Institute of Animal Physiology, Faculty of Science, Safárik University, Kosice, Czechoslovakia.
Ahlersová
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E
Toropila
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M
Datelinka
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I
D000818:Animals; D004305:Dose-Response Relationship, Drug; D005720:Gamma Rays; D050356:Lipid Metabolism; D008055:Lipids / Q000032:analysis* / Q000528:radiation effects; D008297:Male; D010743:Phospholipids / Q000032:analysis / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000737:chemistry* / Q000378:metabolism / Q000528:radiation effects*; D013997:Time Factors
D008055:Lipids; D010743:Phospholipids