[Transient hyperphosphatasemia of infancy].
Transient hyperphosphatasemia of infancy was diagnosed in 4 children hospitalized during a 6-month period (0.3% of all hospitalized children). The characteristic features of this disorder are: 1. elevation of serum alkaline phosphatase (of both liver and bone origin) up to 3-30 times the upper limit of normal for age (usually discovered during intercurrent infection); 2. return of the serum alkaline phosphatase to normal in a few weeks; 3. no residual clinical or laboratory evidence of bone or liver disease. The child is usually less than 5 years old. Recognition of the benign nature of this disorder prevents extensive laboratory workup and unnecessary anxiety.
Garty
B
B
Pediatrics Dept., Beilinson Medical Center, Petah Tikva.
Stayer
D
D
Harell
D
D
Cornblut
B
B
Nitzan
M
M
D000469:Alkaline Phosphatase / Q000097:blood*; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D013997:Time Factors
D000469:Alkaline Phosphatase