title: [Continuous albendazole therapy in alveolar echinococcosis--evaluation of therapeutic effect with computerized tomography and ultrasonography].
abstract: Fifteen cases of alveolar echinococcosis were treated with albendazole in a dosage of 20 mg/kg/d x 30 days for 12-60 courses (25.8 courses in average) and were followed up 1-7 years (48 months in average) with computerized tomography and ultrasonography. Abdominal pain in all the cases, jaundice in 4 and hemoptysis in disappeared 2. In 13 of the 15 cases, the hepatic lesions reduced in size. Among 9 cases examined with computerized tomography, the hepatic lesions were completely calcified in 5 and enclosed with calcified walls in 3. Only one patient with huge and extensive hepatic lesions showed no apparent improvement. No severe adverse reaction was observed. Evidently albendazole was effective in the treatment of alveolar echinococcosis.
authors.affiliation: Institute of Infectious and Parasitic Diseases, Chongqing University ofMedical Sciences.
authors.forename: Y H
authors.initials: YH
authors.lastname: Liu
authors.forename: X G
authors.initials: XG
authors.lastname: Wang
authors.forename: Y T
authors.initials: YT
authors.lastname: Chen
mesh_terms: D000328:Adult; D015766:Albendazole / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D004444:Echinococcosis, Hepatic / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D015766:Albendazole