Long-range doublet correlations in DNA and the coding regions.
Long-range two-body correlations in a DNA sequence should in theory approach a constant value very rapidly with increasing value of the correlation length. It is shown that for most DNA sequences, the long-range correlations exhibit oscillations superimposed on the constant background. These oscillations persist for very large correlation lengths. The oscillations are shown to be three-point cycles and are related to the coding regions in the DNA. A method for discovering the coding regions in DNA sequences is presented. The limitations of the method are discussed.
Mani
G S
GS
Department of Theoretical Physics, Schuster Laboratory, University of Manchester, U.K.
D000595:Amino Acid Sequence; D000818:Animals; D003062:Codon / Q000235:genetics*; D004247:DNA / Q000235:genetics*; D005821:Genetic Techniques; D008957:Models, Genetic; D011506:Proteins / Q000235:genetics; D017386:Sequence Homology, Amino Acid
D003062:Codon; D011506:Proteins; D004247:DNA