[The effect of experimental hepatopathy on the nature of the spontaneous metastasis of Lewis lung carcinoma].
The paper deals with the effect of carbon tetrachloride-induced hepatopathy on pattern of spontaneous dissemination of Lewis tumor transplanted to C57B1/6 mice. Antitumor drugs vincristine and rubomycin prevented dissemination to the liver but failed to arrest spreading to the lung.
Kinzirskiĭ
A S
AS
Galochkina
Z I
ZI
Koroleva
A M
AM
Mikhaĭlevskaia
L L
LL
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000737:chemistry / Q000188:drug therapy / Q000473:pathology*; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology*; D003630:Daunorubicin / Q000627:therapeutic use; D004354:Drug Screening Assays, Antitumor; D005260:Female; D008055:Lipids / Q000032:analysis; D008099:Liver / Q000737:chemistry / Q000187:drug effects / Q000473:pathology; D008175:Lung Neoplasms / Q000737:chemistry / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D014750:Vincristine / Q000627:therapeutic use
D008055:Lipids; D014750:Vincristine; D003630:Daunorubicin
Vliianie éksperimental'noĭ gepatopatii na kharakter spontannogo metastazirovaniia kartsinomy legkikh L'iuis.