title: Circadian variation in the onset of pain of acute myocardial infarction in Indian patients.
abstract: Two hundred patients admitted with acute myocardial infarction (AMI) to the coronary care unit of a tertiary-care-teaching hospital over a period of 1.5 years were studied prospectively, with regard to the time of onset of pain of infarction. The maximum number of infarctions (i.e. 71) (35.6%) occurred between 4.00 AM and 10.00 AM, significantly higher than other 6 hour periods of the day (P < 0.01). Various possible mechanisms leading to this early morning increase in the incidence of AMI and its therapeutic implications are discussed.
authors.affiliation: Cardiolog Medical College, Calicut.
authors.forename: P D
authors.initials: PD
authors.lastname: Kumar
authors.forename: K V
authors.initials: KV
authors.lastname: Sahasranam
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002637:Chest Pain / Q000453:epidemiology* / Q000209:etiology; D002940:Circadian Rhythm; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000453:epidemiology*; D011446:Prospective Studies; D013997:Time Factors