title: Increased interleukin-6 activity in cardiac myxoma with mediastinal lymphadenopathy.
abstract: We report a case of cardiac myxoma with mediastinal lymphadenopathy which seems to be a very rare feature. Laboratory examination revealed high level of interleukin-6 (IL-6) activity in serum. Interestingly, after removal of cardiac myxoma, mediastinal lymphadenopathy disappeared on the chest CT and the level of serum IL-6 was decreased. These findings suggest that IL-6 which was probably derived from myxoma, may have played an important role in the development of lymphadenopathy.
authors.affiliation: Department of Internal Medicine, Saga Medical School, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Kuroki
authors.forename: K
authors.initials: K
authors.lastname: Naitoh
authors.forename: O
authors.initials: O
authors.lastname: Katoh
authors.forename: H
authors.initials: H
authors.lastname: Yamada
authors.forename: T
authors.initials: T
authors.lastname: Itoh
mesh_terms: D005260:Female; D006338:Heart Neoplasms / Q000150:complications / Q000378:metabolism* / Q000601:surgery; D006801:Humans; D015850:Interleukin-6 / Q000096:biosynthesis*; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000209:etiology*; D008477:Mediastinal Diseases / Q000209:etiology*; D008875:Middle Aged; D009232:Myxoma / Q000150:complications / Q000378:metabolism* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D015850:Interleukin-6