title: [The current status of diffuse cutaneous leishmaniasis (DCL) in the state of Maranhão. II. The epidemiological and clinico-evolutionary aspects].
abstract: The authors describe a retrospective and prospective study of 6 patients with diffuse cutaneous leishmaniasis observed in the state of Maranhão, since 1974. The patients come from different rural regions of the state and in all of them Leishmania (Leishmania) amazonensis was the cause five of the patients initiated their disease in the first decade of life. All the patients first had a solitary, nodular lesion, that after a variable period of time, disseminated and acquired other aspects. Sequentially the patients presented multiple nodular and ulcerative lesions, negative Leishmania skin tests and a refractory response to the therapeutic schedules used up to the present.
authors.affiliation: Departamento de Patologia da Universidade Federal do Maranhão, São Luís.
authors.forename: J M
authors.initials: JM
authors.lastname: Costa
authors.forename: A C
authors.initials: AC
authors.lastname: Saldanha
authors.forename: A C
authors.initials: AC
authors.lastname: de Melo e Silva
authors.forename: A
authors.initials: A
authors.lastname: Serra Neto
authors.forename: C E
authors.initials: CE
authors.lastname: Galvão
authors.forename: C de M
authors.initials: Cde M
authors.lastname: Pedroso e Silva
authors.forename: A R
authors.initials: AR
authors.lastname: da Silva
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016774:Leishmaniasis, Diffuse Cutaneous / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D011446:Prospective Studies; D012189:Retrospective Studies; D012737:Sex Factors
vernacular_title: Estado atual da leishmaniose cutânea difusa (LCD) no Estado do Maranhão. II. Aspectos epidemiológicos, clínico-evolutivos.