[Reaction of serum growth hormone in patients with endemic cretinism to arginine and clonidine in continuous excitement tests].
Reaction of serum growth hormone in cretins whose pituitary and thyroid function have returned to normal in IDD-control by using iodized salt to arginine and clonidine in continuous excitement tests ws observed. The result is that during the phase of clonidine excitement, serum growth hormone in cretins was obviously lower than that in normal controls and the reaction peak value, maximum increase value and reaction time all markedly lower than those of the normal controls. 3 cases (18.8%) had no excitement reaction during the phase of arginine excitement, 8 cases (50.0%) no reaction during the phase of clonidine excitement and 2 cases (12.5%) no reaction in the entire process of continuous tests. The results indicate that patients with cretinism suffer from low reserve function of pituitary growth hormone and insufficiency of synthesis even after ther thyroid function has returned to normal.
Kong
D M
DM
Endocrine Unit, Guiyang Medical College Affiliated Hospital.
Shi
Z F
ZF
Zhang
J X
JX
D000293:Adolescent; D001120:Arginine; D003000:Clonidine; D003409:Congenital Hypothyroidism / Q000097:blood*; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D008297:Male; D010901:Pituitary Function Tests; D013960:Thyroid Function Tests
D013006:Growth Hormone; D001120:Arginine; D003000:Clonidine