Adverse drug reactions: report of the Australian Veterinary Association Adverse Drug Reaction Subcommittee, 1992.
Fifty-nine reports of suspected adverse drug reactions (ADRs) were received by the Adverse Drug Reaction Subcommittee of the Australian Veterinary Association from February 1991-March 1992 inclusive. The number of reports received/number of animals involved per species was: dogs (23/24); cats (20/30); horses (4/4); cattle (7/10); sheep (3/745); poultry (1/580); pigs (1/8). Of these, 38 (64%) were classified as definite ADRs and 9 (15%) as probable ADRs. In 10 (17%) reports an ADR could not be substantiated or there was insufficient information available to make a decision. Two reports involved veterinarians inadvertently overdosing animals. Eighteen reports involved apparent hypersensitivity reactions and 6 reports involved probable drug interactions. Four reports involved the use of drugs at appropriate doses but in inappropriate clinical situations, and 3 reports were associated with 'off-label' use.
Maddison
J E
JE
Department of Pharmacology, University of Sydney, New South Wales.
D000818:Animals; D000829:Animals, Domestic; D001315:Australia; D002415:Cats; D002417:Cattle; D004285:Dogs; D004342:Drug Hypersensitivity / Q000662:veterinary*; D062787:Drug Overdose / Q000662:veterinary; D064420:Drug-Related Side Effects and Adverse Reactions; D006736:Horses; D011200:Poultry; D011358:Product Surveillance, Postmarketing; D012756:Sheep; D013552:Swine