Evaluation of motor unit firing rates by standard concentric needle electromyography.
Motor unit firing rates at slight voluntary contraction were studied by standard concentric needle electromyography. Employing digital signal analysis techniques firing rates of motor units (MU) could be evaluated as long as four or less different MUs were activated in the vicinity of the concentric needle electrode. The extension of the recording area is defined by the recording properties of the electrode and the upper limit of rise-time for all MUPs being evaluated. Distant MUs, generating volume conducted potentials with rise-times greater than 0.8 ms, were excluded. In biceps muscles of 15 healthy controls the firing rate of the MU activated first was evaluated at that moment, when a second MU was recruited and was found to be 12.1 +/- 2.1 Hz (mean +/- S.D., n = 40). The firing rate of the fastest MU out of 2, 3, or 4 simultaneously active MUs was 10.7 +/- 2.5 Hz, 10.9 +/- 2.5 Hz and 10.6 +/- 2.4 Hz respectively. Hence at low innervation level there is no increase of firing rate with rising number of activated MUs. The upper normal limit of MU firing rate (3 sigma interval) is calculated as 17 Hz, irrespective whether 1, 2, 3 or 4 MUs are active within the recording area. Fifteen patients with partially denervated biceps muscles were investigated. Maximal firing rates were increased in 10 patients, all showing moderate or severe paresis (grade 1-3). In 10 patients suffering from myopathies firing rates always were normal. The presented data may serve as an additional criterion in evaluating MU firing rates during standard clinical EMG.
Gunreben
G
G
Neurologische Universitätsklinik Würzburg, FRG.
Schulte-Mattler
W
W
D000200:Action Potentials / Q000502:physiology*; D000328:Adult; D004566:Electrodes; D004576:Electromyography / Q000295:instrumentation*; D004867:Equipment Design; D006801:Humans; D008297:Male; D009046:Motor Neurons / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology; D009132:Muscles / Q000294:innervation / Q000503:physiopathology; D009135:Muscular Diseases / Q000503:physiopathology; D009339:Needles; D010243:Paralysis / Q000503:physiopathology; D010523:Peripheral Nervous System Diseases / Q000503:physiopathology; D009435:Synaptic Transmission / Q000502:physiology; D013997:Time Factors