title: Molecular cloning and sequence analysis of the cDNA for northern pike (Esox lucius) growth hormone.
abstract: The complete nucleotide sequence of the northern pike (Esox lucius) cDNA for pregrowth hormones was determined from clones derived from a pituitary gland cDNA library. Seventeen cDNA clones were isolated from a single mRNA species. A cDNA of 1,227 nucleotides was sequenced and found to encode a polypeptide of 209 amino acid residues, which included a putative signal sequence of 22 amino acid residues. Sequence comparison of the northern pike growth hormone gene to other known growth hormone genes revealed similarities closest to other members of the superorder Protacanthopterygii, which includes the Salmonidae family (i.e., salmon and trout).
authors.affiliation: Department of Genetics, University of Minnesota, Minneapolis 55455.
authors.forename: J F
authors.initials: JF
authors.lastname: Schneider
authors.forename: S H
authors.initials: SH
authors.lastname: Myster
authors.forename: P B
authors.initials: PB
authors.lastname: Hackett
authors.forename: K S
authors.initials: KS
authors.lastname: Guise
authors.forename: A J
authors.initials: AJ
authors.lastname: Faras
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA; D005399:Fishes / Q000235:genetics; D013006:Growth Hormone / Q000235:genetics*; D006801:Humans; D008322:Mammals / Q000235:genetics; D008969:Molecular Sequence Data; D010802:Phylogeny; D012487:Salmonidae / Q000235:genetics*; D017386:Sequence Homology, Amino Acid
chemical_list: D013006:Growth Hormone; D004247:DNA