title: [Mitochondrial myopathy of progressive external ophthalmoplegia].
abstract: Ten cases of blepharoptosis and chronic progressive oculomuscular paralysis are reported among which three had limb muscular weakness. Sex: male 5, female 5. Age: 16-58 years old. Age of onset: 7-38 years old.
  
  
  METHODS
  2-26 years. Muscle biopsy showed ragged red fibers, abnormal mitochondria and paracrystalline mitochondrial inclusions under both light and electron microscopy. All cases were diagnosed as CPED (chronic progressive external ophthalmoplegia) clinically and abnormal mitochondria pathologically.
authors.affiliation: Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing.
authors.forename: Y P
authors.initials: YP
authors.lastname: Guo
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D008931:Mitochondria, Muscle / Q000648:ultrastructure*; D009132:Muscles / Q000473:pathology / Q000648:ultrastructure; D017246:Ophthalmoplegia, Chronic Progressive External / Q000175:diagnosis* / Q000473:pathology