title: The effect of antibiotic therapy on the oral health of cystic fibrosis children.
abstract: This study examined the relationship between antibiotic usage and plaque, gingivitis and dental caries experience in a group of children suffering from cystic fibrosis. Their scores for plaque, gingivitis and dental caries were compared with those of healthy control children who were individually matched on the basis of age, sex and social class. Significant negative relationships were noted between (i) antibiotic usage during the 4 weeks prior to examination and plaque and gingivitis scores, and (ii) antibiotic usage since the age of 6 years and DMFT. It is suggested that antibiotic therapy may be a major cause of the lower levels of dental disease observed in cystic fibrosis children.
authors.affiliation: Department of Paediatric and Preventive Dentistry, School of Clinical Dentistry, Belfast, Northern Ireland.
authors.forename: M J
authors.initials: MJ
authors.lastname: Kinirons
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications* / Q000188:drug therapy; D004245:DMF Index; D003731:Dental Caries / Q000150:complications*; D003773:Dental Plaque / Q000150:complications*; D003774:Dental Plaque Index; D005260:Female; D005891:Gingivitis / Q000150:complications*; D006801:Humans; D008297:Male; D009660:Northern Ireland; D009909:Oral Health; D010512:Periodontal Index
chemical_list: D000900:Anti-Bacterial Agents