[The effect of proanthocyanidins from Alhagi pseudoalhagi (M. B.) Desv on the course of experimental myocardial infarct].
Intravenous proantocyanidin isolated from Alhagi pseudoalhagi (M. B.) Desv, 5-10 mg/kg, has no effects on the general hemodynamics and cardiac contractility of intact rats and rabbits. The agent given to animals with experimental myocardial infarction reduces serum creatinine phosphate levels and lipid peroxidation both in the myocardium and serum, as estimated by the amount of malonic dialdehyde and dienic conjugates), normalizes free fat acid content and cardiac phospholipid spectrum. At the same time the size of a myocardial necrotic zone became diminished.
Khushbaktova
Z A
ZA
Syrov
V N
VN
Kuliev
Z
Z
Bashirova
N S
NS
Shadieva
Z
Z
Gorodeyskaia
E A
EA
Medvedev
O S
OS
D000818:Animals; D000872:Anthocyanins / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D006439:Hemodynamics / Q000187:drug effects; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D009206:Myocardium / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D010936:Plant Extracts / Q000627:therapeutic use*; D044945:Proanthocyanidins; D011817:Rabbits; D051381:Rats
D000872:Anthocyanins; D010743:Phospholipids; D010936:Plant Extracts; D044945:Proanthocyanidins; C013221:proanthocyanidin
Vliianie proantotsianidinov iz iantaka lozhnogo na techenie éksperimental'nogo infarkta miokarda.