Neural invasion in intraductal carcinoma of the breast.
Although perineural invasion in a malignancy favors the diagnosis of invasive over in situ carcinoma, we report a case of cribriform intraduct carcinoma of the breast showing perineural invasion. The in situ nature of the lesion is supported by the finding of an intact actin-positive myoepithelial cell layer around the cribriform growths and the preservation of lobular architecture.
Tsang
W Y
WY
Institute of Pathology, Queen Elizabeth Hospital, Hong Kong.
Chan
J K
JK
D000368:Aged; D001940:Breast / Q000294:innervation*; D001943:Breast Neoplasms / Q000473:pathology*; D002278:Carcinoma in Situ / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness; D009417:Nerve Tissue / Q000473:pathology