[Changes due to age in the regenerating axons of the adult rat].
Muscle reinnervation after nerve crush was observed in rats at different ages with a combined technique that simultaneously demonstrates nerve endings and endplates. At early times of reinnervation the amount of sprouting was higher in older rats than in younger rats; according to this finding an enhanced number of polyinnervated endplates was found in older rats. A similar enhancement of sprouting and polyinnervation was observed during muscle reinnervation of vitamin E deficient rats, supporting the proposed analogy between vitamin E deficiency and aging.
Ambrogini
P
P
Istituto di Scienze Morfologiche, Università di Urbino.
Cecchini
T
T
Ciaroni
S
S
Del Grande
P
P
D000375:Aging / Q000502:physiology*; D000818:Animals; D001369:Axons / Q000502:physiology*; D008297:Male; D009045:Motor Endplate / Q000648:ultrastructure; D009409:Nerve Crush; D009416:Nerve Regeneration / Q000502:physiology*; D009469:Neuromuscular Junction / Q000648:ultrastructure*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012584:Sciatic Nerve / Q000502:physiology; D014811:Vitamin E Deficiency / Q000503:physiopathology
Modificazioni dovute all'età negli assoni rigeneranti di ratti adulti.