Hashimoto's thyroiditis in HTLV-I carriers.
We describe two HTLV-I virus carriers who have biopsy-proven Hashimoto's thyroiditis. The first patient, a 64-year-old female, has had goiter and hypothyroidism since the age of 56. The second patient, a 66-year-old male, developed hyperthyroidism and goiter at the age of 44, but at present he is hypothyroid. Both patients are positive for anti-thyroid antibodies and anti-HTLV-I virus antibody. Findings of the thyroid biopsy specimens were consistent with Hashimoto's thyroiditis. These data suggest that Hashimoto's thyroiditis develops in HTLV-I carriers who have no clinical evidence of HAM/TSP.
Kawai
H
H
First Department of Internal Medicine, School of Medicine, University of Tokushima, Japan.
Saito
M
M
Takagi
M
M
Tsuchihashi
T
T
Arii
Y
Y
Kondo
A
A
Iwasa
M
M
Hirose
T
T
Hizawa
K
K
Saito
S
S
D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis; D015139:Blotting, Southern; D002353:Carrier State; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D015368:Human T-lymphotropic virus 1 / Q000235:genetics / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D013961:Thyroid Gland / Q000276:immunology / Q000473:pathology; D013963:Thyroid Hormones / Q000032:analysis; D013967:Thyroiditis, Autoimmune / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology*
D000914:Antibodies, Viral; D004279:DNA, Viral; D013963:Thyroid Hormones