[A method for isolating a complex epoxide-containing antigen and its use for the diagnosis of allergic diseases].
Specific complex antigen, based on human serum albumin and epichlorhydrine was proved to be useful in the diagnosis of individual hypersensitivity to the epoxide pitches and epichlorhydrine. Lymphocytes' blast transformation with 3H-timidine was proved to be the most sensitive reaction in the use of specific complex antigen during the diagnosis. The stated immune reaction can be used for the diagnosis of allergy before the clinical manifestations.
Shevchenko
A M
AM
Bordonos
V G
VG
Iavorovskiĭ
A P
AP
Veremeĭ
M I
MI
Kuiun
L A
LA
D000941:Antigens / Q000302:isolation & purification*; D009783:Dermatitis, Occupational / Q000175:diagnosis* / Q000209:etiology; D004811:Epichlorohydrin / Q000276:immunology; D000939:Epitopes / Q000302:isolation & purification; D004852:Epoxy Compounds / Q000009:adverse effects / Q000276:immunology*; D006801:Humans; D007159:Immunologic Tests / Q000379:methods; D008213:Lymphocyte Activation; D012709:Serum Albumin / Q000276:immunology; D013936:Thymidine; D014316:Tritium
D000941:Antigens; D000939:Epitopes; D004852:Epoxy Compounds; D012709:Serum Albumin; D004811:Epichlorohydrin; D014316:Tritium; D013936:Thymidine
Sposob polucheniia époksidsoderzhashchego kompleksnogo antigena i ego ispol'zovanie dlia diagnostiki allergicheskikh zabolevaniĭ.