[Influence of ethyl alcohol on resistance of lobular blood vessels of human placentas during in vitro perfusion].
25 human placentae lobuli obtained from normal, term deliveries were examined. Two-sided, closed perfusion according to modified Schneider method was used. Pressure of perfusion was recorded independently in maternal and fetal circulation using mercurial manometer and Ludwig kymograph++. Ethyl alcohol was dosed in single portion of 50 mg (A-1 group) and 250 mg (A-2 group) in 10% concentration (real concentration respectively 0.1 and 0.5%). In control group 0.9% NaCl was used. Decrease of the blood-vessel resistance in maternal and fetal circulation was observed. The relaxation was dependent on ethyl alcohol concentration.
Lopucki
M
M
Kliniki Połoznictwa AM, Lublinie.
Lopucka
M
M
D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D010920:Placenta / Q000098:blood supply*; D014655:Vascular Resistance / Q000187:drug effects*
D000431:Ethanol
Wpływ alkoholu etylowego na opory naczyniowe zrazika łozyska ludzkiego w warunkach perfuzji in vitro.