[The use of lyophilized blood serum for determining the 3-HAA antigen in patients with precancerous diseases and cancer of the bladder].
3-OAK antigen was determined by immunodiffusion in agar by means of immune sera containing antibodies against 3-OAK. In patients with cancer of the urinary bladder the percentage of detecting 3-OAK-Ag in the native serum was 76.9 while in lyophilized it was 41.9. In patients with pretumorous diseases (leukoplakia, chronic cystitis, papillomas) their values were 64.1 and 56.1 respectively. It is concluded that lyophilized blood serum may be used in the clinical practice for immunological and serological examinations.
Klimenko
I A
IA
Sakalo
V S
VS
Korosteleva
T A
TA
Belokhvostova
A T
AT
Sakalo
A V
AV
D015095:3-Hydroxyanthranilic Acid; D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D005612:Freeze Drying; D006801:Humans; D005779:Immunodiffusion; D007971:Leukoplakia / Q000175:diagnosis*; D010212:Papilloma / Q000175:diagnosis*; D011230:Precancerous Conditions / Q000175:diagnosis*; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D015095:3-Hydroxyanthranilic Acid
Ispol'zovanie liofilizirovannoĭ syvorotki krovi dlia opredeleniia 3-OAK-antigena u bol'nykh s predopukholevymi zabolevaniiami i rakom mochevogo puzyria.