title: Anti-hepatitis C virus antibodies amongst Italian homo-bisexual males.
abstract: The authors report on an anti-hepatitis C virus antibody (HCV Ab) prevalence (6.9%) in 622 homo-bisexual males from Northern Italy, voluntarily attending an HIV and STDs screening program in the period 1984-89. The anti-HCV antibody prevalence shows a significant correlation with: i) presence of serological markers for HBV (O.R. = 3.12, 95% C.I. = 1.53-6.52) and HIV (O.R. = 12.09; C.I. = 6.52-22.52) infection; ii) a stable relationship with an anti-HCV antibody positive partner (O.R. = 7.79; 95% C.I. = 2.50-23.90); iii) more than twenty different male partners per year (O.R. = 2.55; 95% C.I. = 1.17-5.66). These data demonstrate the existence of a sexual transmission of HCV among homosexuals. This route might contribute in maintaining endemic levels of HCV infection in the homo-bisexual population and it might represent an important way of spreading the virus in the general population too.
authors.affiliation: Istituto Malattie Infettive, Università di Bologna, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Ricchi
authors.forename: M
authors.initials: M
authors.lastname: Borderi
authors.forename: P
authors.initials: P
authors.lastname: Costigliola
authors.forename: R
authors.initials: R
authors.lastname: Miniero
authors.forename: G
authors.initials: G
authors.lastname: Sprovieri
authors.forename: F
authors.initials: F
authors.lastname: Chiodo
mesh_terms: D000328:Adult; D001727:Bisexuality; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000302:isolation & purification*; D006526:Hepatitis C / Q000453:epidemiology* / Q000635:transmission; D018937:Hepatitis C Antibodies; D006716:Homosexuality; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D012747:Sexual Partners
chemical_list: D006508:Hepatitis Antibodies; D018937:Hepatitis C Antibodies