[Hereditary motor and sensory neuropathy].
The report consisted of 10 cases of hereditary motor and sensory neuropathy (HMSN). There were 7 males and 3 females. Their ages ranged from 11 to 42 (average 24.6) years, ages of onset varied from 7 to 34 (average 17.3) years. Hereditary history was showed in 4 cases. The clinical features of all 10 cases had peroneal muscular atrophy, 8 of 10 cases also had involvement of the upper limbs, 7 of 10 cases had pes arcuatus. The conduction velocity was obviously slow in 5 cases and slightly slow in the others. Oion-bulb hypertrophic neuropathy was demonstrated in sural nerve biopsies of 5 cases. Neuronal axonal degeneration were found in the remaining 5 cases. Clinical classification, clinical features and pathological characteristics were discussed.
Guo
Y P
YP
Dept. of Neurology, PUMC Hospital, Beijing.
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002648:Child; D005260:Female; D015417:Hereditary Sensory and Motor Neuropathy / Q000145:classification / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D012583:Schwann Cells / Q000648:ultrastructure; D013497:Sural Nerve / Q000473:pathology / Q000648:ultrastructure