title: Progressive bilateral nasal alar collapse: a dominantly inherited trait.
abstract: We describe a 47-year-old woman with progressive bilateral collapse of the alae nasi first noted at age 16 years. Her dizygotic twin daughters have similar nasal collapse beginning at age 20 years. This condition appears to be inherited as a dominant trait. Although plastic surgical correction has been successful for a phenotypically similar condition due to trauma, surgical correction must be considered cautiously in individuals with an atraumative, possibly inherited, progressive form of the disorder.
authors.affiliation: Department of Human Genetics, Medical College of Virginia/Virginia Commonwealth University, Richmond 23298.
authors.forename: H
authors.initials: H
authors.lastname: Cole
authors.forename: J
authors.initials: J
authors.lastname: Bodurtha
authors.forename: B A
authors.initials: BA
authors.lastname: Salbert
authors.forename: B
authors.initials: B
authors.lastname: Wolf
mesh_terms: D000328:Adult; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008875:Middle Aged; D009666:Nose / Q000473:pathology*; D010641:Phenotype; D014429:Twins, Dizygotic