[Phenotype analysis of mononuclear cells from endomyocardial biopsy specimens in patients with viral myocarditis and dilated cardiomyopathy].
The distribution and phenotype of mononuclear cells from endomyocardial biopsy (EMB) specimens in patients with viral myocarditis (VMC, 25 cases) and dilated cardiomyopathy (DCM, 10 cases) were studied. T-lymphocytes, including T-h/i (T-helper/induced) cells in VMC and T-c/s (T-cytotoxic/suppressor) cells in DCM, were predominated in the infiltrating mononuclear cells within these specimens. The morphological relationship between infiltration of T-lymphocytes and pathological changes of myocardium was also observed, but both macrophages and B-lymphocytes were absent.
Li
W
W
Tongji Hospital, Tongji Medical University, Wuhan.
D000328:Adult; D001706:Biopsy; D002311:Cardiomyopathy, Dilated / Q000473:pathology*; D004699:Endocardium / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000382:microbiology / Q000473:pathology*; D010641:Phenotype; D016176:T-Lymphocyte Subsets / Q000473:pathology*; D006377:T-Lymphocytes, Helper-Inducer / Q000473:pathology; D050378:T-Lymphocytes, Regulatory / Q000473:pathology; D014777:Virus Diseases / Q000473:pathology*