title: Hypoxemia in thalassemia.
abstract: Data are reviewed describing hypoxemia, a newly identified feature in thalassemia. Evidence indicates platelet aggregation in the pulmonary circulation as being a key factor leading to hypoxemia and cor-pulmonale with right heart failure.
authors.affiliation: Thalassemia Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Fucharoen
authors.forename: P
authors.initials: P
authors.lastname: Winichagoon
authors.forename: N
authors.initials: N
authors.lastname: Siritanaratkul
authors.forename: D
authors.initials: D
authors.lastname: Sonakul
authors.forename: U
authors.initials: U
authors.lastname: Chantaraksri
authors.forename: A
authors.initials: A
authors.lastname: Bunyaratvej
authors.forename: A
authors.initials: A
authors.lastname: Piankijagum
authors.forename: P
authors.initials: P
authors.lastname: Wasi
mesh_terms: D001241:Aspirin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D001784:Blood Gas Analysis; D004176:Dipyridamole / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D005500:Follow-Up Studies; D006333:Heart Failure / Q000209:etiology; D006801:Humans; D000860:Hypoxia / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D010974:Platelet Aggregation; D011652:Pulmonary Circulation; D011660:Pulmonary Heart Disease / Q000209:etiology; D013156:Splenectomy; D013789:Thalassemia / Q000150:complications* / Q000601:surgery
chemical_list: D004176:Dipyridamole; D001241:Aspirin