[Study on the incidence of coal mine pneumoconiosis and lung cancer in Beijing coal mining district].
Thirty-two cases (20.13%) of primary lung cancer from 159 coal miner autopsies of Beijing coal mining area are reported in this study. The ratio of peripheral type to central type of lung cancer is 1.9:1; among them the adenocarcinoma is the most frequent (56.25%). Pathological examination shows that the diffuse interstitial type is the most common lung cancer. The occurrence of adenocarcinoma and the degree of lung fibrosis is related. The average number of ferruginous bodies is 190.2 +/- 8.06 in adenocarcinoma, 165.4 +/- 2.60 in squamous carcinoma, the difference is statistically significant (P < 0.05). The amount of trace elements-Fe, Al, Al/Si and Zn/Cu in lung with cancer is less than that without cancer. This article also discusses the relationship between coal mine pneumoconiosis with lung cancer of the formation of ferruginous bodies in the lung tissue of coal miner autopsies, which resembles the lung cancer combined with asbestosis. We also discussed the carcinogenesis of trace element in lung.
Wang
H Y
HY
Institute of Occupational Medicine of China National Coal Corporation, Beijing.
D000230:Adenocarcinoma / Q000473:pathology; D002681:China / Q000453:epidemiology; D003032:Coal Mining; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000473:pathology; D011009:Pneumoconiosis / Q000453:epidemiology* / Q000473:pathology; D014131:Trace Elements / Q000032:analysis
D014131:Trace Elements