[Effect of home oxygen therapy on patients with chronic obstructive lung diseases].
Effects of 4 year of long-term oxygen therapy (LTOT) in 130 COPD patients were evaluated. All suffered from severe airways obstruction (FEV1 = 0.84 l), hypoxaemia (PaO2 = 55 mm Hg) and pulmonary hypertension (PAP = 29 mm Hg). The mean oxygen breathing hours averaged 15.2 h/day. Forty seven patients (36%) died during the observation period. LTOT did not prevent the progress of respiratory insufficiency-fall inc C and FEV. However it stabilized pulmonary arterial pressure and haematocrit. It was found that FEV1 < 0.76 l, PaO2 < 52 mm Hg, PAP > 30 mm Hg and oxygen breathing hours < 12/day bear risk of early death despite LTOT. The variables correlated best with survival were FEV1 and PaO2.
Sliwiński
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Kliniki Chorób Płuc Instytutu Gruźlicy i Chorób Płuc, Warszawie.
D000368:Aged; D005260:Female; D006699:Home Care Services / Q000458:organization & administration*; D006801:Humans; D000860:Hypoxia / Q000209:etiology / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D008134:Long-Term Care / Q000458:organization & administration; D008173:Lung Diseases, Obstructive / Q000150:complications / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000008:administration & dosage* / Q000097:blood; D011175:Positive-Pressure Respiration / Q000379:methods*; D012119:Respiration / Q000502:physiology*; D012131:Respiratory Insufficiency / Q000209:etiology / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors
D010100:Oxygen
Efekty domowego leczenia tlenem u chorych na przewlekła obturacyjna chorobe płuc.