title: Ischemic stroke treated with Ligusticum chuanxiong.
abstract: Ligusticum Chuanxiong and its effective components were studied in the treatment of ischemic stroke, a common emergent disease in China. Some injections of the medicines, including Ligusticum, Ligustrazine, Ligustylid and ferulic acid, were tested clinically and experimentally. The results showed that the effects of the drugs were the same as or even better than those of the controls, such as papaverine, dextran and aspirin-persantin. They could improve brain microcirculation through inhibiting thrombus formation and platelet aggregation as well as blood viscosity.
authors.affiliation: Xiyuan Hospital, China Academy of Traditional Chinese Medicine, Beijing.
authors.forename: K J
authors.initials: KJ
authors.lastname: Chen
authors.forename: K
authors.initials: K
authors.lastname: Chen
mesh_terms: D000818:Animals; D002561:Cerebrovascular Disorders / Q000188:drug therapy*; D003373:Coumaric Acids / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D011719:Pyrazines / Q000627:therapeutic use*
chemical_list: D003373:Coumaric Acids; D004365:Drugs, Chinese Herbal; D010975:Platelet Aggregation Inhibitors; D011719:Pyrazines; C004999:ferulic acid; C017953:tetramethylpyrazine