title: Cytoarchitectural development of the human dentate nucleus: a Golgi study.
abstract: Golgi-stained sections of the human cerebellar dentate nucleus (DN) at various gestational ages were examined to study the dendritic proliferation and maturation of the DN neurons. Bipolar cells were seen at 14-15 weeks. By 19-20 weeks, three cell types were identifiable: bipolar, hemispheric and pyriform. The cells of the dorsomedial region matured earlier than those of the ventrolateral region. In addition to the above cell types, multipolar and nuclear boundary cells were observable at 24-25 weeks. The five cell types persisted during subsequent development. At no stage of development was any neuronal organizational pattern apparent. A remarkable dendritic proliferation occurred at 27-28 weeks. Spines and filiform processes were seen at 34 weeks of intrauterine life.
authors.affiliation: Department of Anatomy, All India Institute of Medical Sciences, New Delhi.
authors.forename: A
authors.initials: A
authors.lastname: Hayaran
authors.forename: S
authors.initials: S
authors.lastname: Wadhwa
authors.forename: V
authors.initials: V
authors.lastname: Bijlani
mesh_terms: D002529:Cerebellar Nuclei / Q000196:embryology / Q000648:ultrastructure*; D003712:Dendrites / Q000648:ultrastructure; D005865:Gestational Age; D006801:Humans; D009474:Neurons / Q000648:ultrastructure; D011192:Potassium Dichromate; D012835:Silver Nitrate; D016622:Silver Staining
chemical_list: D012835:Silver Nitrate; D011192:Potassium Dichromate