title: [The immunoenzyme test system for detection of HIV-1 antigens based on using immune polyclonal anti-HIV serum and monoclonal antibodies against gene GAG HIV-1 proteins].
abstract: The paper describes the enzyme immunoassay system for detection of human immunodeficiency virus antigens, which is based on the use of rabbit anti-HIV antibodies and monoclonal antibodies to HIV-1 gene proteins gag. The system may be useful in the examination of laboratory and clinical samples to reveal both free and conjugated antigens in the composition of immune complexes. The sensitivity of the assay system under development is 0.5 ng/ml at 100% specificity.
authors.forename: G N
authors.initials: GN
authors.lastname: Trushinskaia
authors.forename: V I
authors.initials: VI
authors.lastname: Simonov
authors.forename: N E
authors.initials: NE
authors.lastname: Makarova
authors.forename: D N
authors.initials: DN
authors.lastname: Nosik
authors.forename: A A
authors.initials: AA
authors.lastname: Kushch
authors.forename: R A
authors.initials: RA
authors.lastname: Gibadulin
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis / Q000235:genetics / Q000276:immunology*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000235:genetics / Q000276:immunology*; D015683:Gene Products, gag / Q000276:immunology*; D015488:HIV Antigens / Q000032:analysis* / Q000276:immunology; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D007106:Immune Sera / Q000235:genetics / Q000276:immunology*; D007124:Immunoenzyme Techniques; D011817:Rabbits
chemical_list: D000911:Antibodies, Monoclonal; D015683:Gene Products, gag; D015488:HIV Antigens; D007106:Immune Sera
vernacular_title: Immunofermentnaia test-sistema dlia vyiavleniia antigenov VICh-1, osnovannaia na primenenii immunnoĭ poliklonal'noĭ anti-VICh syvorotki i monoklonal'nykh antitel k belkam gena GAG VICh-1.