title: Oral fluorescein angiography and fluoroscopy: determination of plasma fluorescein levels and clinical application.
abstract: One hundred oral fluorescein angiographic explorations were performed in 85 patients of both sexes, mean age 55.57 years, and range 8 to 77 years. Fluorescein was administered as one 250-mg (15 patients) or 500-mg (70 patients) capsule per 15 kg of body weight. In 15 fasting and 15 postprandial patients administered 500-mg capsules, no significant differences by group were found between fluorescein plasma levels. Fundus fluorescence under slitlamp illumination was poor for patients receiving the lower dosage of fluorescein, whereas at the higher dosage it was visible in all but one patient. The best filters were found to be a Kodak-Wratten 47A for the excitation filter and Kodak-Wratten 8 for the barrier filter. With a conventional fundus camera and fluorescein angiography filters, good photographs were achieved in all cases. The integrity of the blood-retina barriers was explored for various chorioretinal pathologies.
authors.affiliation: Department of Ophthalmology, Hospital General de Galicia, University of Santiago, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Gómez-Ulla
authors.forename: A
authors.initials: A
authors.lastname: Malvar
authors.forename: M
authors.initials: M
authors.lastname: Parafita
authors.forename: P
authors.initials: P
authors.lastname: Polo
authors.forename: I
authors.initials: I
authors.lastname: Seoane
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D001813:Blood-Retinal Barrier / Q000502:physiology; D002214:Capsules; D002648:Child; D004435:Eating; D005260:Female; D019793:Fluorescein; D005451:Fluorescein Angiography; D005452:Fluoresceins / Q000008:administration & dosage / Q000493:pharmacokinetics*; D005471:Fluoroscopy; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000175:diagnosis
chemical_list: D002214:Capsules; D005452:Fluoresceins; D019793:Fluorescein