title: Hepatocellular carcinoma associated with arteriohepatic dysplasia in a 4-year-old girl.
abstract: Hepatocellular carcinoma and obliterated hepatic bile duct were found at postmortem examination in a 4-year-old girl with arteriohepatic dysplasia (Alagille's syndrome). AFP level was extremely high. Liver cirrhosis was present on percutaneous needle biopsy 9 months before she succumbed in progressive liver failure. Episodes of repeated gastrointestinal, life-threatening hemorrhages occurred during the last 6 months of her life. Histopathologic findings of the eyes were documented at autopsy.
authors.affiliation: Department of Pediatrics, University Hospital, Lund, Sweden.
authors.forename: A N
authors.initials: AN
authors.lastname: Békássy
authors.forename: S
authors.initials: S
authors.lastname: Garwicz
authors.forename: T
authors.initials: T
authors.lastname: Wiebe
authors.forename: I
authors.initials: I
authors.lastname: Hägerstrand
authors.forename: O A
authors.initials: OA
authors.lastname: Jensen
mesh_terms: D016738:Alagille Syndrome / Q000150:complications* / Q000175:diagnosis; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000209:etiology*; D002675:Child, Preschool; D005123:Eye / Q000473:pathology; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology