The diagnosis and steroid "pulse" therapy of systemic lupus erythematosus associated with mental disturbances in the general hospital.
Twenty-eight patients suffering from systemic lupus erythematosus (SLE) associated with mental disturbances were analyzed clinically (1983-1990). Although no characteristic features of the mental disturbances of SLE were found, it should be differentiated from steroid- or chronic renal failure-induced mental disorders. One gram of methylprednisolone intravenously daily for 3 days was recommended as a pulse therapy to treat the mental disturbances of SLE. In this group, the mental disturbances of SLE showed improvement or disappearance in 18 of 25 patients (72%) after pulse therapy.
Li
S
S
PUMC Hospital, CAMS, Beijing.
Wang
J
J
D000293:Adolescent; D000328:Adult; D003520:Cyclophosphamide / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000188:drug therapy*; D008775:Methylprednisolone / Q000008:administration & dosage*; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage
D003520:Cyclophosphamide; D011241:Prednisone; D008775:Methylprednisolone