title: [The effect of smoking on the long-term outcome of closure of perforated gastric and duodenal ulcer].
abstract: Examined were 164 patients at the long-term period after closure of a perforative ulcer of the stomach and duodenum. The negative effect of smoking on acid production and protective barrier of gastroduodenal mucosa leading to worsened healing of an ulcer closed and its recurrence in 50% of the patients operated on has been established. It was noted that in smokers, irrespective of a number of the cigarettes being smoked, an excellent and good long-term result was observed 2.5 times less often, and a poor one--3 times more often than in non-smokers.
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Volkov
authors.forename: I L
authors.initials: IL
authors.lastname: Volkova
mesh_terms: D000328:Adult; D004381:Duodenal Ulcer / Q000150:complications; D006801:Humans; D008875:Middle Aged; D010439:Peptic Ulcer Perforation / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D011182:Postoperative Care; D012008:Recurrence; D012907:Smoking / Q000009:adverse effects; D013276:Stomach Ulcer / Q000150:complications; D013997:Time Factors; D016896:Treatment Outcome
vernacular_title: Vliianie kureniia na otdalennyĭ iskhod zashivaniia probodnoĭ iazvy zheludka i dvenadtsatiperstnoĭ kishki.