Coping and the ineffectiveness of coping influence the outcome of in vitro fertilization through stress responses.
The effect of a coping-ineffectiveness of coping construct and of psychoendocrine stress responses upon the outcome of in vitro fertilization treatment was investigated in 40 women. Women with a high Zung depression score, high active coping, high avoidance, and a high expression of emotion have lower pregnancy rates. The mechanisms for this personality effect are not clear, although the desensitization-stimulation process (FSH, E2 concentrations) seems to be involved. The psychoendocrinological responses to the stress of oocyte retrieval and embryo transfer are important: Women with high anticipatory state anxiety levels and high anticipatory cortisol concentrations have lower pregnancy rates. The influence of prolactin stress concentrations is unclear: Women with high prolactin concentrations seem to have more oocytes but lower fertilization rates.
Demyttenaere
K
K
Department of Obstetrics and Gynecology, University Hospital Gasthuisberg, Catholic University, Leuven, Belgium.
Nijs
P
P
Evers-Kiebooms
G
G
Koninckx
P R
PR
D000223:Adaptation, Psychological / Q000502:physiology*; D000328:Adult; D001007:Anxiety / Q000097:blood / Q000523:psychology; D001143:Arousal / Q000502:physiology*; D003863:Depression / Q000097:blood / Q000523:psychology; D004624:Embryo Transfer / Q000523:psychology; D005260:Female; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D011247:Pregnancy / Q000502:physiology*; D011388:Prolactin / Q000097:blood
D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D006854:Hydrocortisone