Toxicological findings in a fatal case of acebutolol self-poisoning.
A fatal case of acebutolol self-poisoning is presented. After single-step liquid-liquid alkaline extraction, acebutolol was identified by using an HPLC/DAD screening procedure. By means of a specific HPLC method, acebutolol was then quantified in a large range of postmortem samples. The blood acebutolol concentration was 34.7 micrograms/mL. The tissue distribution of the drug is discussed in the light of the existing literature.
Tracqui
A
A
Institut de Médecine Légale, Strasbourg, France.
Kintz
P
P
Wendling
P
P
Ritter-Lohner
S
S
Mangin
P
P
Jaeger
A
A
D000070:Acebutolol / Q000032:analysis / Q000506:poisoning*; D000293:Adolescent; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D013405:Suicide
D000070:Acebutolol