title: Immunomodulatory agents in the laboratory and clinic.
abstract: This paper reviews naturally occurring and synthetic compounds that either enhance immune defences or lower both natural and acquired immunity. Immunomodulatory agents used both for laboratory study and clinically for the management of immunologically based diseases are considered.
authors.affiliation: Department of Surgery and Molecular Genetics, University of Pittsburgh Medical Center, PA 15213.
authors.forename: A K
authors.initials: AK
authors.lastname: Nüssler
authors.forename: A W
authors.initials: AW
authors.lastname: Thomson
mesh_terms: D000210:Acute-Phase Reaction / Q000276:immunology; D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000305:Adrenal Cortex Hormones / Q000494:pharmacology; D000477:Alkylating Agents / Q000494:pharmacology; D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000963:Antimetabolites / Q000494:pharmacology; D016207:Cytokines / Q000276:immunology; D006801:Humans; D007109:Immunity / Q000187:drug effects*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D016897:Respiratory Burst / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D000305:Adrenal Cortex Hormones; D000477:Alkylating Agents; D000911:Antibodies, Monoclonal; D000963:Antimetabolites; D016207:Cytokines; D007166:Immunosuppressive Agents