Fast and slow twitch skeletal muscle fibres differ in their distribution of Na channels near the endplate.
Sodium channel distributions were measured in fast and slow twitch rodent skeletal muscle fibres using the loose patch voltage clamp technique. Large differences were found between these fibre types with respect to Na channel density in the perijunctional region. Fast twitch fibres exhibited a large increase in Na channel density near the endplate, while slow twitch fibres did not.
Milton
R L
RL
Indiana University School of Medicine, Ball State University, Muncie, IN 47306.
Lupa
M T
MT
Caldwell
J H
JH
D000818:Animals; D008564:Membrane Potentials; D051379:Mice; D009045:Motor Endplate / Q000502:physiology* / Q000648:ultrastructure; D009132:Muscles / Q000502:physiology* / Q000648:ultrastructure; D051381:Rats; D015222:Sodium Channels / Q000502:physiology* / Q000648:ultrastructure
D015222:Sodium Channels