title: A family case of beta-thalassemia minor and hemoglobin Queens: alpha 34 (B15) Leu-Arg.
abstract: We report a Korean family case of beta-thalassemia minor and Hb Queens. This is the first case report of Hb Queens in Korea. A 43-year-old male and his four family members had beta-thalassemia minor which is very rare in Korea. Incidentally, an alpha chain variant with a high isoelectric point was also found in two other family members without clinical problems and was finally identified as alpha 34 (B15) Leu-Arg or Hemoglobin Queens.
authors.affiliation: Department of Clinical Pathology, Seoul National University College of Medicine, Korea.
authors.forename: N Y
authors.initials: NY
authors.lastname: Lee
authors.forename: H I
authors.initials: HI
authors.lastname: Cho
authors.forename: S I
authors.initials: SI
authors.lastname: Kim
authors.forename: B K
authors.initials: BK
authors.lastname: Kim
authors.forename: Y
authors.initials: Y
authors.lastname: Ohba
authors.forename: Y
authors.initials: Y
authors.lastname: Hattori
mesh_terms: D000328:Adult; D001120:Arginine / Q000235:genetics; D005260:Female; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006801:Humans; D007723:Korea; D007930:Leucine / Q000235:genetics; D008297:Male; D010375:Pedigree; D017086:beta-Thalassemia / Q000097:blood / Q000235:genetics*
chemical_list: D006455:Hemoglobins, Abnormal; C035047:hemoglobin Queens; D001120:Arginine; D007930:Leucine