title: [Adrenoleukodystrophy: clinical and histopathological study of a case associated to the use of abortifacient agents in the second month of pregnancy].
abstract: The authors report a case of adrenoleukodystrophy in a 8 years old male patient whose mother has taken several abortive drugs during the first three months of pregnancy. The disease was progressive starting with auditory, visual and mental disturbances, followed by neurovegetatives and motor changes with convulsion and fetal position. At the final stage the patient became blind, deaf, quadriplegic and dementiated. Death resulted from lung infection. The diagnosis was confirmed by the CSF, electrophysiological, radiological and necropsy findings. Necropsy changes in the brain and adrenal cortex are detailed.
authors.affiliation: Faculdade de Ciências Médicas (FCM) da Fundação do Ensino Superior de Pernambuco (FESP), Brasil.
authors.forename: P R
authors.initials: PR
authors.lastname: de Brito-Marques
authors.forename: R J
authors.initials: RJ
authors.lastname: de Melo
authors.forename: L
authors.initials: L
authors.lastname: Barraquer i Bordas
mesh_terms: D000019:Abortifacient Agents / Q000009:adverse effects*; D000326:Adrenoleukodystrophy / Q000139:chemically induced* / Q000150:complications / Q000473:pathology; D001921:Brain / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012141:Respiratory Tract Infections / Q000209:etiology
chemical_list: D000019:Abortifacient Agents
vernacular_title: Adrenoleucodistrofia. Estudo clínico e histopatológico de um caso associado ao uso de abortivos no segundo mês de gestação.