title: Management of oral health in persons with HIV infection.
abstract: Prevention and treatment of oral disease is required to maintain quality of life and to improve prognosis of patients infected with the human immunodeficiency virus (HIV). Management requires a team approach, and close collaboration with the appropriate responsible physicians and other health care workers is necessary. Oral infection is frequent and usually opportunistic, and management is based on certain principles. Infections may disseminate and can be persistent and severe; multiple concurrent or consecutive infections with different microorganisms are frequent; fungal, viral, and parasitic infections are rarely curable; and long-term antimicrobial therapy may be required. This article reviews the management of oral candidiasis, hairy leukoplakia, and infections with herpes simplex virus, varicella-zoster virus, and cytomegalovirus. The management of Kaposi's sarcoma, lymphomas, aphthous ulceration, gangrenous stomatitis, bleeding, xerostomia, and adverse drug reactions is also described. Treatment should avoid further immunosuppression and inducement of xerostomia or caries, and should be designed to avoid adverse drug reactions and possible drug interactions.
authors.affiliation: University Department of Oral Medicine, Surgery and Pathology, Bristol Dental Hospital and School, England.
authors.forename: C
authors.initials: C
authors.lastname: Scully
authors.forename: G
authors.initials: G
authors.lastname: McCarthy
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000188:drug therapy; D000935:Antifungal Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000009:adverse effects; D002180:Candidiasis, Oral / Q000150:complications / Q000188:drug therapy; D003730:Dental Care for Persons with Disabilities; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006566:Herpesviridae Infections / Q000150:complications / Q000188:drug therapy; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000209:etiology / Q000532:radiotherapy; D009059:Mouth Diseases / Q000150:complications* / Q000188:drug therapy*; D009062:Mouth Neoplasms / Q000209:etiology* / Q000628:therapy*; D012514:Sarcoma, Kaposi / Q000188:drug therapy / Q000209:etiology / Q000532:radiotherapy; D013281:Stomatitis, Aphthous / Q000139:chemically induced / Q000150:complications / Q000188:drug therapy; D014412:Tumor Virus Infections / Q000150:complications / Q000188:drug therapy
chemical_list: D000935:Antifungal Agents; D000998:Antiviral Agents