[The interrelation of the secretory activity of the myocardium with its hypertrophic characteristics in patients with ischemic heart disease].
Evaluation of the concentration of atrial natriuretic peptide, angiotensin P, renin activity in the blood of the coronary sinus and aorta in 18 patients with IHD and hypertrophy of the left ventricle during development of induced ischemia revealed that in left ventricular hypertrophy secretion of atrial natriuretic peptide by the myocardium is reduced. The level of this reduction depends on the kind of hypertrophy. Dilatation of the left ventricle cavity furthers exhaustion of the secretory function of the ischemic myocardium.
Ianovskiĭ
G V
GV
Moĭbenko
M A
MA
Stadniuk
L A
LA
Savitskiĭ
S Iu
SIu
Belonozhko
A G
AG
D000328:Adult; D000804:Angiotensin II / Q000097:blood; D009320:Atrial Natriuretic Factor / Q000097:blood; D006321:Heart / Q000503:physiopathology*; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000097:blood / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood / Q000503:physiopathology*; D012083:Renin / Q000097:blood
D000804:Angiotensin II; D009320:Atrial Natriuretic Factor; D012083:Renin
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