title: Brain natriuretic peptide (BNP)-like immunoreactivity in the central nervous system of the crested newt.
abstract: The distribution of brain natriuretic peptide (BNP)-like immunoreactivity (ir) was studied in the brain of a urodele amphibian, the crested newt Triturus carnifex Laur. BNP-like immunoreactive neurons were found mainly in the caudal hypothalamus (retro- and supra-chiasmatic areas) and in the preoptic area. A widespread innervation throughout the brainstem as far as the spinal cord was also observed. By double immunostaining (after section incubation with a-BNP and a-tyrosine hydroxylase-TH-antibodies), close topographical relationships between BNP-like and TH-like immunoreactive neurons within the hypothalamus were found.
authors.affiliation: Dipartimento di Biologia Animale, Università di Torino, Italy.
authors.forename: M F
authors.initials: MF
authors.lastname: Franzoni
authors.forename: M
authors.initials: M
authors.lastname: Canonaco
authors.forename: A
authors.initials: A
authors.lastname: Frova
authors.forename: R
authors.initials: R
authors.lastname: Tavolaro
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D001933:Brain Stem / Q000737:chemistry; D005260:Female; D005455:Fluorescent Antibody Technique; D007031:Hypothalamus / Q000737:chemistry / Q000201:enzymology; D007124:Immunoenzyme Techniques; D008297:Male; D020097:Natriuretic Peptide, Brain; D009419:Nerve Tissue Proteins / Q000032:analysis* / Q000276:immunology; D013116:Spinal Cord / Q000737:chemistry; D014319:Triturus; D014446:Tyrosine 3-Monooxygenase / Q000032:analysis / Q000276:immunology
chemical_list: D009419:Nerve Tissue Proteins; D020097:Natriuretic Peptide, Brain; D014446:Tyrosine 3-Monooxygenase