Canine distemper virus infection in a masked palm civet (Paguma larvata).
A free-living masked palm civet (Paguma larvata) died after exhibiting signs of canine distemper (CD). The microscopic lesions consisted of cytoplasmic and intranuclear eosinophilic inclusion bodies, bronchointerstitial pneumonia, non-purulent encephalitis accompanied by demyelination and lymphocytic depletion in various lymphoid tissues. CD virus-specific antigens were demonstrated immunohistochemically in intracellular eosinophilic inclusions, which were ultrastructurally confirmed to be viral nucleocapsids. From these findings, the present case was diagnosed as CD virus infection in a masked palm civet.
Machida
N
N
Department of Veterinary Pathology, Tokyo University of Agriculture and Technology, Japan.
Izumisawa
N
N
Nakamura
T
T
Kiryu
K
K
D000818:Animals; D002335:Carnivora / Q000382:microbiology*; D004198:Disease Susceptibility / Q000662:veterinary; D004216:Distemper / Q000382:microbiology* / Q000473:pathology; D004217:Distemper Virus, Canine / Q000302:isolation & purification* / Q000472:pathogenicity; D005260:Female; D013045:Species Specificity