[The determination of measles antibody titers in the latex agglutination reaction].
A new latex agglutination test (LAT) for detection of antibodies to measles virus in blood sera was developed. The latex diagnosticum consists of polymeric microspheres of national make carrying on their surface covalently bound measles virus antigen. The data on the specificity and sensitivity of the test are presented, and the results of titrations of blood sera from schoolchildren by traditional HI test and LAT are compared. LAT was shown to be highly sensitive, much simpler than the available methods for detection of measles antibodies and more economic, and therefore may be recommended for mass surveys.
Aleksander
S K
SK
Fidler
L M
LM
Lukin
Iu V
IuV
Iuminova
N V
NV
Krasnova
V P
VP
Liashenko
V A
VA
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D005069:Evaluation Studies as Topic; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007841:Latex Fixation Tests / Q000295:instrumentation / Q000379:methods*; D008459:Measles virus / Q000276:immunology* / Q000302:isolation & purification; D011817:Rabbits; D012680:Sensitivity and Specificity
D000914:Antibodies, Viral
Opredelenie titrov protivokorevykh antitel v reaktsii lateks-aggliutinatsii.