title: [Focused extracorporeal pyrotherapy. Initial experimental results].
abstract: The objective of this study was to develop an apparatus allowing the generation of a high temperature (exceeding 80 degrees C) in a precise focus (20 mm x 2 mm) by means of extracorporeal elastic waves. The treatment time at high temperatures is brief and administered in sequences of 4 to 7 seconds. In vitro studies on blocks of polyurethane demonstrated melting of the plastic at the focal point. Studies on plastic spheres introduced into the bladder of the pig demonstrated melting of the sphere without any alteration in the tissues in the wave path. Studies of cellular viability of bladder carcinoma cultures demonstrated a significant difference after 48 hours between the non-treated control group and the group of cells submitted to high temperatures. This technique, called Pyrotherapy, should be promising if the preliminary results are confirmed.
authors.affiliation: Centre Médico-Chirurgical de la Porte de Choisy, Département d'Urologie, Paris.
authors.forename: G
authors.initials: G
authors.lastname: Vallancien
authors.forename: D
authors.initials: D
authors.lastname: Chopin
authors.forename: C
authors.initials: C
authors.lastname: Davila
authors.forename: B
authors.initials: B
authors.lastname: Guiillonneau
authors.forename: E
authors.initials: E
authors.lastname: Perreira
authors.forename: B
authors.initials: B
authors.lastname: Veillon
authors.forename: J M
authors.initials: JM
authors.lastname: Brisset
authors.forename: J
authors.initials: J
authors.lastname: Andre-Bougaran
mesh_terms: D000818:Animals; D002295:Carcinoma, Transitional Cell / Q000628:therapy; D002470:Cell Survival; D003124:Colorimetry; D006358:Hot Temperature; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation / Q000379:methods; D008297:Male; D011140:Polyurethanes / Q000737:chemistry; D011470:Prostatic Hyperplasia / Q000628:therapy; D013552:Swine; D014407:Tumor Cells, Cultured; D014464:Ultrasonic Therapy / Q000295:instrumentation / Q000379:methods*; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000628:therapy
chemical_list: D011140:Polyurethanes
vernacular_title: Pyrothérapie extra-corporelle focalisée. Premiers résultats expérimentaux.