[Urinary citrate determination in normal persons and in patients with recurrent urinary calculi].
The presence of citric acid in urine and its ability to bind calcium ions forming a soluble complex are well recognized and has led to the suggestion that citric acid may play an important role in preventing renal calcium stone disease. In this study the 24-hour urinary excretion was measured with a specific enzymatic method in 48 normal subjects and in a group of 46 non selected patients with recurrent urolithiasis. Hypocitraturia was detected in 18/46 patients (39.1%) and was the unique metabolic abnormality in 6 (13%).
Noronha
I de L
Ide L
Grupo Multidisciplinar de Estudos da Calculose Urinária, Hospital das Clínicas da Faculdade de Medicina, Universidade de São Paulo.
Andriolo
A
A
Wroclawski
E
E
Chade
J
J
Lucon
A M
AM
Arap e Emil
S
S
Sabbaga
E
E
D000328:Adult; D000368:Aged; D002951:Citrates / Q000652:urine*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D014545:Urinary Calculi / Q000652:urine*
D002951:Citrates
Dosagem de citrato urinário em indivíduos adultos normais e em pacientes com calculose urinária recidivante.