Idiopathic, aseptic, effusive, fibrinous, nonconstrictive pericarditis with tamponade in a standardbred filly.
A Standardbred filly was admitted for evaluation of pleuritis and pneumonia. Heart rate was 80 to 120 beats/min, and the pulse was barely palpable. Thoracic and abdominal ultrasonography and echocardiography revealed substantial pericardial effusion with cardiac tamponade, fibrinous pericarditis, pleural effusion, and ascites. Initial electrocardiography revealed normal sinus rhythm with decreased amplitude of the QRS complexes consistent with pericardial effusion. Following thoracentesis, echocardiogram-guided pericardiocentesis was performed. Bacterial culture yielded no growth from any of the fluids, and bacteria were not seen on cytologic examination. Initial treatment included broad-spectrum antibiotic treatments, IV fluid therapy, and anti-inflammatory agent administration. On the basis of negative culture results, an immune-mediated cause was considered, and dexamethasone was instituted in a decreasing dosage regimen. Pericardial effusion, ventral edema, and ascites began to resolve within 3 days after beginning dexamethasone treatment. Thirty days following discharge, the filly was reexamined, and at that time, the prognosis for athletic performance was considered good so the horse was returned to race training. The final diagnosis in this case was idiopathic, effusive, nonconstrictive pericarditis with tamponade. Early identification, clinical understanding, and application of knowledge of the pathophysiologic mechanisms of pericarditis in horses, combined with use of diagnostic aids such as ultrasonography and aggressive therapy consisting of effusion drainage, pericardial lavage, antibiotics that penetrate the pericardium, and corticosteroids when indicated are critical for a successful outcome in horses with pericarditis.
Robinson
J A
JA
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.
Marr
C M
CM
Reef
V B
VB
Sweeney
R W
RW
D000818:Animals; D001201:Ascites / Q000150:complications / Q000662:veterinary; D002305:Cardiac Tamponade / Q000150:complications / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D003937:Diagnosis, Differential; D004562:Electrocardiography / Q000662:veterinary; D005260:Female; D006734:Horse Diseases / Q000175:diagnosis* / Q000628:therapy; D006736:Horses; D010490:Pericardial Effusion / Q000150:complications / Q000662:veterinary; D010493:Pericarditis / Q000150:complications / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D010996:Pleural Effusion / Q000150:complications / Q000662:veterinary