title: Clearance of plasminogen activator--a major determinant of plasma concentration: therapeutic and diagnostic implications.
authors.affiliation: Centre for Human Drug Research, University Hospital, Leiden, The Netherlands.
authors.forename: A F
authors.initials: AF
authors.lastname: Cohen
authors.forename: K
authors.initials: K
authors.lastname: Burggraaf
authors.forename: A
authors.initials: A
authors.lastname: de Boer
authors.forename: C
authors.initials: C
authors.lastname: Kluft
mesh_terms: D000818:Animals; D003328:Coronary Thrombosis / Q000188:drug therapy*; D006801:Humans; D008099:Liver / Q000378:metabolism*; D008102:Liver Circulation; D008657:Metabolic Clearance Rate; D008954:Models, Biological; D009203:Myocardial Infarction / Q000188:drug therapy*; D010960:Plasminogen Activators / Q000097:blood / Q000378:metabolism* / Q000627:therapeutic use*; D011994:Recombinant Proteins / Q000097:blood / Q000378:metabolism / Q000627:therapeutic use; D010959:Tissue Plasminogen Activator / Q000097:blood / Q000378:metabolism* / Q000627:therapeutic use
chemical_list: D011994:Recombinant Proteins; D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator