title: Issues related to dust aerosols in the magnesite industry. I. Chamber exposure.
abstract: The present paper is an overview of the experimental research into the effects of flue magnesite dust in the magnesite industry in which the raw material (magnesite) is processed into refractory magnesite clinker. The issues related to dust are divided into two problem areas: a) dust aerosol arising in the process of ore mining and consisting largely of magnesite (MgCO3) and b) dust aerosol originating during ore baking in rotatory furnaces and made up mostly of MgO. Thus, larger groups of people become exposed to these aerosols as a result of solid particles escaping into the atmosphere than in the case of occupational exposure. Experimental research carried out on laboratory animals after chamber exposure provided findings on the deposition, retention and elimination of magnesite dust, on impaired balance between magnesium and calcium leading to damage of biological membranes, on how the immune profile or reproduction and embryogenesis is impacted as well as on the possible interaction with sodium salicylate as a result of an impaired acid base balance. These findings are followed up by evidence produced in the course of biological monitoring (Part II).
authors.affiliation: Institute of Ecobiology, Slovak Academy of Sciences, Bratislava, Czechoslovakia.
authors.forename: E
authors.initials: E
authors.lastname: Reichrtová
authors.forename: L
authors.initials: L
authors.lastname: Takác
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D002118:Calcium / Q000097:blood; D015194:Diffusion Chambers, Culture; D004372:Ducks / Q000196:embryology; D004391:Dust / Q000009:adverse effects*; D005314:Embryonic and Fetal Development / Q000187:drug effects; D004781:Environmental Exposure / Q000009:adverse effects*; D004910:Erythrocyte Membrane / Q000187:drug effects; D005260:Female; D008168:Lung / Q000187:drug effects / Q000378:metabolism; D008274:Magnesium / Q000009:adverse effects* / Q000097:blood / Q000737:chemistry / Q000493:pharmacokinetics; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009079:Mucociliary Clearance; D051381:Rats; D017208:Rats, Wistar; D012098:Reproduction / Q000187:drug effects
chemical_list: D004391:Dust; C005479:magnesium carbonate; D008274:Magnesium; D002118:Calcium