Thiamin triphosphate does not affect contraction of skinned fibers.
Effects of thiamin triphosphate (TTP) on contraction of chemically skinned fibers prepared from the extensor digitorum longus muscle of guinea pigs were investigated. The addition of TTP at 40 microM concentration affected neither Ca2+ uptake nor Ca(2+)-induced Ca2+ release by sarcoplasmic reticulum. Contraction of myofibril was not affected by TTP either.
Shioda
T
T
Department of Biochemistry, Hiroshima University School of Medicine, Japan.
Kawasaki
T
T
D000818:Animals; D002118:Calcium / Q000502:physiology; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects* / Q000502:physiology; D012519:Sarcoplasmic Reticulum / Q000187:drug effects / Q000502:physiology; D013838:Thiamine Triphosphate / Q000494:pharmacology*
D013838:Thiamine Triphosphate; D002118:Calcium