title: Results of early surgery for infantile esotropia in normal and neurologically impaired infants.
abstract: A prospective study was performed over a 4-year period of 56 infants presenting with infantile esotropia to assess development of binocularity after surgical alignment before 2 years of age. In 50% of cases infantile esotropia was associated with neurological problems or prematurity. Forty-three cases have undergone surgery (mean age 15.7 months +/- 3.46); 86% were aligned (+/- 10 dioptres) at 2 years. Eighty-seven per cent of normal children and 74% of children with neurological problems or prematurity were aligned at last follow-up (mean 27.2 months since surgery). Tests of fusion and stereopsis have to date been possible upon 21 'successfully' aligned infants and although most have evidence of peripheral sensory fusion none showed stereopsis to more than one test. Although early surgery achieves a good cosmetic result in normal children and those with neurological problems, our findings question its ability to promote the development of even gross stereopsis in most children.
authors.affiliation: Department of Ophthalmology, Addenbrooke's Hospital, Cambridge, UK.
authors.forename: S J
authors.initials: SJ
authors.lastname: Charles
authors.forename: A T
authors.initials: AT
authors.lastname: Moore
mesh_terms: D003867:Depth Perception; D004948:Esotropia / Q000209:etiology / Q000523:psychology / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000601:surgery*; D009422:Nervous System Diseases / Q000150:complications*; D009801:Oculomotor Muscles / Q000601:surgery*; D011446:Prospective Studies