Severe falciparum malaria: survival with oral therapy.
A case of severe falciparum hyperparasitaemia with trophozoites in greater than 35% of the patient's erythrocytes, relative lack of clinical symptoms and no organ complication is described. The patient, a 26-month old African child, was treated with oral mefloquine with prompt clearance of fever and parasitaemia in 24 and 48 hours respectively. No untoward sequelae was observed during 75 days of periodic clinical assessment.
Sowunmi
A
A
Department of Pharmacology and Therapeutics, University of Ibadan, Nigeria.
Walker
O
O
Akindele
J A
JA
D000284:Administration, Oral; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016778:Malaria, Falciparum / Q000097:blood / Q000188:drug therapy* / Q000469:parasitology; D015767:Mefloquine / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D012720:Severity of Illness Index
D015767:Mefloquine