title: [Multiparameter analysis of pharmacological specificity of 3-benzylchromone (homoisoflavone) derivatives on different pharmacological tests in vitro].
abstract: For access to structure/activity/specificity of a serie of eight 3-benzylchromones (homoisoflavones), the authors used multivariate analysis. The obtained results allow to envisage the synthesis of molecules more specific of one of the three types of activities studied: angioprotective, antihistaminic, antiallergic.
authors.affiliation: URA 401 du CNRS, Muséum National d'Histoire Naturelle, Paris.
authors.forename: J C
authors.initials: JC
authors.lastname: Doré
authors.forename: S
authors.initials: S
authors.lastname: Kirkiacharian
authors.forename: C
authors.initials: C
authors.lastname: Viel
mesh_terms: D001593:Benzyl Compounds / Q000737:chemistry / Q000494:pharmacology*; D002867:Chromones / Q000737:chemistry / Q000494:pharmacology*; D066298:In Vitro Techniques; D015999:Multivariate Analysis; D012680:Sensitivity and Specificity; D013329:Structure-Activity Relationship; D013678:Technology, Pharmaceutical / Q000706:statistics & numerical data
chemical_list: D001593:Benzyl Compounds; D002867:Chromones
vernacular_title: Analyse multiparamétrique de la spécificité pharmacologique de dérivés de la 3-benzylchromone (homoisoflavone) sur différents tests pharmacologiques in vitro.