[Comparison of erythrocyte concentrations of ATP, ADP, AMP and 2,3-BPG in storage of five different additive solutions and in serum].
In this study, we compared the ability of serum and of 5 additive solutions for the liquid storage of red blood cells to preserve the cellular contents of 2,3-BPG and the adenylate nucleotides ATP, ADP and AMP. As to the adenylates, PAGGS-M showed the best results. However, the difference to SAG-M was significant only after 7 weeks. On the other hand, serum appears to be the best medium for the conservation of 2,3-BPG. Between the 1st and 3rd week of storage, the decrease of 2,3-BPG was somewhat slower in PAGGS-M and SAG-M compared with the other 3 additive solutions.
von Eisenhart-Rothe
B
B
Abteilung für Transfusionsmedizin und Transplantationsimmunologie, Chirurgische Universitätsklinik, Hamburg-Eppendorf, BRD.
Ganschow
I
I
Dominka
T
T
Kühnl
P
P
D019794:2,3-Diphosphoglycerate; D000225:Adenine; D000244:Adenosine Diphosphate / Q000097:blood*; D000249:Adenosine Monophosphate / Q000097:blood*; D000255:Adenosine Triphosphate / Q000097:blood*; D016913:Blood Component Transfusion; D001793:Blood Preservation; D004163:Diphosphoglyceric Acids / Q000097:blood*; D004905:Erythrocyte Aging / Q000502:physiology; D005947:Glucose; D006151:Guanosine; D006801:Humans; D010710:Phosphates; D012965:Sodium Chloride; D013012:Sorbitol; D013997:Time Factors
D004163:Diphosphoglyceric Acids; C053620:PAGGS-sorbitol solution; D010710:Phosphates; D006151:Guanosine; D019794:2,3-Diphosphoglycerate; D000249:Adenosine Monophosphate; D012965:Sodium Chloride; D013012:Sorbitol; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D005947:Glucose; D000225:Adenine
Vergleich der erythrozytären Konzentrationen von ATP, ADP, AMP und 2,3-BPG bei Lagerung in fünf verschiedenen additiven Lösungen und in Serum.