title: Transvaginal intratubal insemination, ectopic pregnancy and treatment by single-dose parenteral methotrexate.
abstract: We report a case of a woman with ectopic pregnancy with fetal cardiac activity after ovulation induction and transvaginal intratubal insemination by tactile sensation. The patient was successfully treated by single-dose methotrexate (MTX) (77 mg or 50 mg/m2 given intramuscularly). Control hysterosalpingograms showed no tubal patency on the involved side. Potential advantages and hazards of transvaginal intratubal insemination and single-dose MTX for ectopic pregnancy are discussed.
authors.affiliation: Department of Obstetrics and Gynaecology, Faculty of Medicine, Hospital Clinic i Provincial, Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Balasch
authors.forename: J L
authors.initials: JL
authors.lastname: Ballesca
authors.forename: F
authors.initials: F
authors.lastname: Fábregues
authors.forename: B
authors.initials: B
authors.lastname: Puerto
authors.forename: R
authors.initials: R
authors.lastname: Casamitjana
authors.forename: J A
authors.initials: JA
authors.lastname: Vanrell
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood; D002996:Clomiphene / Q000494:pharmacology; D005187:Fallopian Tubes / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007315:Insemination, Artificial / Q000009:adverse effects*; D008727:Methotrexate / Q000494:pharmacology*; D010062:Ovulation Induction / Q000379:methods; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D014463:Ultrasonography; D014599:Uterus / Q000000981:diagnostic imaging
chemical_list: D006063:Chorionic Gonadotropin; D002996:Clomiphene; D008727:Methotrexate