Putative periodontal pathogens on titanium implants and teeth in experimental gingivitis and periodontitis in beagle dogs.
The microflora around titanium implants and teeth in 4 beagle dogs was analyzed in order to follow the longitudinal development from healthy conditions to experimental gingivitis and periodontitis. A 2-month plaque control program was performed to establish healthy conditions on titanium implants and control teeth (baseline, day 0). Subgingival bacterial samples and radiographs were obtained. The plaque control was ceased and all measurements were repeated on day 21 (gingivitis). A new period of plaque control was initiated to re-establish healthy conditions (day 49). A cotton ligature was placed subgingivally around the implants and the control teeth to induce tissue breakdown. The ligatures were removed on day 91. The study was completed with registrations on day 121 (periodontitis). No significant microbiological difference was found between titanium implants and teeth in healthy conditions and in gingivitis and periodontitis. The mean total viable count increased 10 times on implants as well as on teeth. Streptococci were dominating at baseline: 40.2% on implants and 60.6% on teeth and decreased in gingivitis to 11.7% and 5.4%. When periodontitis had developed, the proportion of streptococci was < 1%. At baseline few Porphyromonas gingivalis and Prevotella intermedia were detected. They increased at gingivitis to 37.4% and 21.0%; when periodontitis developed, they comprised about 25.0%. Microbial colonization and establishment on titanium implants with healthy gingiva, experimental gingivitis and periodontitis follow the same pattern as on teeth.
Leonhardt
A
A
Faculty of Odontology, University of Göteborg, Sweden.
Berglundh
T
T
Ericsson
I
I
Dahlén
G
G
D000818:Animals; D001439:Bacteroides / Q000302:isolation & purification; D002206:Capnocytophaga / Q000302:isolation & purification; D015921:Dental Implants / Q000009:adverse effects*; D003773:Dental Plaque / Q000382:microbiology*; D004285:Dogs; D005673:Fusobacterium / Q000302:isolation & purification; D005891:Gingivitis / Q000382:microbiology*; D010518:Periodontitis / Q000382:microbiology*; D016459:Prosthesis-Related Infections; D013291:Streptococcus / Q000302:isolation & purification; D014025:Titanium
D015921:Dental Implants; D014025:Titanium