title: Cathepsin G, a polymorphonuclear cell protease, affects the fibrinolytic system by releasing PAI-1 from endothelial cells and platelets.
authors.affiliation: Istituto di Ricerche Farmacologiche Mario Negri, Consorzio Mario Negri Sud, Santa Maria Imbaro, Chieti, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Pintucci
authors.forename: L
authors.initials: L
authors.lastname: Iacoviello
authors.forename: C
authors.initials: C
authors.lastname: Amore
authors.forename: V
authors.initials: V
authors.lastname: Evangelista
authors.forename: C
authors.initials: C
authors.lastname: Cerletti
authors.forename: M B
authors.initials: MB
authors.lastname: Donati
mesh_terms: D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D056649:Cathepsin G; D002403:Cathepsins / Q000097:blood / Q000494:pharmacology*; D002478:Cells, Cultured; D017077:Culture Media, Conditioned; D004730:Endothelium, Vascular / Q000187:drug effects / Q000378:metabolism*; D005109:Extracellular Matrix / Q000378:metabolism; D006801:Humans; D009504:Neutrophils / Q000201:enzymology; D017395:Plasminogen Activator Inhibitor 1 / Q000097:blood / Q000302:isolation & purification / Q000378:metabolism*; D012697:Serine Endopeptidases; D015843:Serpins / Q000494:pharmacology; D014471:Umbilical Veins
chemical_list: D017077:Culture Media, Conditioned; D017395:Plasminogen Activator Inhibitor 1; D015843:Serpins; D002403:Cathepsins; D012697:Serine Endopeptidases; C534094:CTSG protein, human; D056649:Cathepsin G