title: [Sex hormone-binding globulin (SHBG) under physiological and pathological conditions].
abstract: The concentration of sex hormone-binding globulin (SHBG) in blood depends on the sex, age, metabolic status of the organism, liver function, and gonad function. The circadian rhythm of somatotropin secretion is an important regulator of SHBG synthesis and secretion, and its passage from vascular bed to the tissues depends on somatomedin-C. The concentration of SHBG in the serum is thus the resultant of the synthesis of this glycoprotein in the liver and the ability of its uptake in the cells of target tissues for sex hormones.
authors.affiliation: I Katedry i Zakładu Patofizjologii, Zabrzu.
authors.forename: K
authors.initials: K
authors.lastname: Zwirska-Korczala
authors.forename: Z
authors.initials: Z
authors.lastname: Ostrowska
authors.forename: B
authors.initials: B
authors.lastname: Buntner
mesh_terms: D002940:Circadian Rhythm / Q000502:physiology; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D012738:Sex Hormone-Binding Globulin / Q000378:metabolism*
chemical_list: D012738:Sex Hormone-Binding Globulin; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone
vernacular_title: Białko wiazace hormony płciowe (SHBG) w fizjologii i patologii.