title: 5-Lipoxygenase inhibitors isolated from the mushroom Boletopsis leucomelas (Pers.) Fayod.
abstract: Terphenyl compounds, tentatively named Bl-I (1), Bl-II (2), Bl-III (3), Bl-IV (4) and Bl-V (5), showing 5-lipoxygenase inhibitory activity have been isolated from the mushroom Boletopsis leucomelas (Pers.) Fayod. On the basis of physico-chemical and spectral evidence, they were concluded to be a series of cycloleucomelone-leucoacetates.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Takahashi
authors.forename: R
authors.initials: R
authors.lastname: Kudo
authors.forename: G
authors.initials: G
authors.lastname: Kusano
authors.forename: S
authors.initials: S
authors.lastname: Nozoe
mesh_terms: D000818:Animals; D001487:Basidiomycota / Q000737:chemistry*; D006168:Guinea Pigs; D016859:Lipoxygenase Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D009504:Neutrophils / Q000187:drug effects / Q000201:enzymology
chemical_list: D016859:Lipoxygenase Inhibitors