[Effect of a mechanical insufficiency of lymph outflow from the uterus on the course of pregnancy in rats under experimental conditions].
For lack of literature data studies of disturbed lymph outflow on pregnancy and foetus development in rats were accomplished. The studies were carried out on matured female inbred Wistar rats. In experimental group a mechanical insufficiency of lymph outflow from pregnant uterus was performed by means of ligature of lymphatics and excision of regional lymph nodes (i.e. lumbar, sacral and renal lymph nodes). The control groups were sham-operated and normal pregnant animals. Surgical procedures were performed at first day of pregnancy (determined by means of spermatozoa presence in vaginal smears). Animal were examined on 7th and 17th day of pregnancy and at delivery. The results from sham-operated group were identical with normal pregnant animals. In experimental group of 17th day of pregnancy was a lower number of foetuses, greater total number of resorption places, lower mean weight of placenta and foetus, higher mean placental-foetal ratio and longer duration of pregnancy compared with control groups. In delivery group it was obtained a lower mean weight of a new-born rat than in control group. The difference between values obtained in experimental group and values obtained in control group had a statistical significance. The estimation of obtained results allowed to draw a conclusion: the mechanical insufficiency of lymph outflow from uterus can has a negative influence for course of pregnancy and development of foetus in rats.
Ciszek
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Katedry i Zakładu Anatomii Opisowej i Topograficznej Sl. AM, Zabrzu.
Mikusek
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J
Slusarczyk
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Ciszek
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D000818:Animals; D005314:Embryonic and Fetal Development / Q000502:physiology*; D005260:Female; D008196:Lymph / Q000502:physiology; D008197:Lymph Node Excision; D008208:Lymphatic System / Q000502:physiology*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D014599:Uterus / Q000098:blood supply*
Wpływ niewydolnego odpływu chłonki typu mechanicznego z macicy na przebieg ciazy u szczura w warunkach eksperymentalnych.