Case-control study of congenital malformations.
To determine potentially teratogenic influences in Belgrade, a group of 113 mothers who gave birth to severely malformed infants and a control group of 195 mothers with normal infants were interviewed using a structured questionnaire. Statistically significant differences between the two groups were found in the mother's family history of congenital malformations (P < 0.05) and the mother's diseases during the pregnancy (P < 0.01). Infections in the first trimester were particularly more prevalent in case mothers (OR = 7.70; P < 0.01). Mothers did not differ significantly according to exposure to organic solvents, supportive therapy during the pregnancy, use of oral contraceptives, or other personal habits.
Ananijevic-Pandey
J
J
Institute of Social Medicine, Statistics and Health Research Medical Faculty, University of Belgrade, Yugoslavia.
Jarebinski
M
M
Kastratovic
B
B
Vlajinac
H
H
Radojkovic
Z
Z
Brankovic
D
D
D016022:Case-Control Studies; D000013:Congenital Abnormalities / Q000453:epidemiology* / Q000235:genetics; D005260:Female; D006801:Humans; D016017:Odds Ratio; D011247:Pregnancy; D011248:Pregnancy Complications; D011795:Surveys and Questionnaires; D015022:Yugoslavia / Q000453:epidemiology