title: [Macroprolactinoma at 6 years of age: diagnostic difficulties].
abstract: Prolactinoma is rare in childhood and adolescence. The earliest known diagnosis was reported in a patient at 8 years of age. We report the case of a sellar tumor found in a 6 years old girl. After a long symptomatic period she was brought for treatment. At this time she had partial papillar atrophy, hyperprolactinemia, and diminished reserve of growth hormone and cortisol. Due to rapid visual deterioration, she was submitted to a frontotemporal craniotomy for suspected craniopharyngioma. The tumor tissue immunohistochemistry was positive for prolactin. It is concluded that prolactinoma must be considered in differential diagnosis of sellar tumors in childhood since it benefits from a less aggressive therapy.
authors.affiliation: Disciplina de Endocrinologia da Fundação Faculdade Federal de Ciências Médicas de Porto Alegre (FFFCLMPA), Brasil.
authors.forename: M da C
authors.initials: Mda C
authors.lastname: Oliveira
authors.forename: D D
authors.initials: DD
authors.lastname: Abech
authors.forename: L M
authors.initials: LM
authors.lastname: Barbosa-Coutinho
authors.forename: N P
authors.initials: NP
authors.lastname: Ferreira
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006966:Hyperprolactinemia / Q000209:etiology; D009896:Optic Atrophy / Q000209:etiology; D010908:Pituitary Hormones, Anterior / Q000097:blood; D010911:Pituitary Neoplasms / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D015175:Prolactinoma / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D014057:Tomography, X-Ray Computed
chemical_list: D010908:Pituitary Hormones, Anterior; D006854:Hydrocortisone
vernacular_title: Macroprolactinoma aos 6 anos de idade. Dificuldades diagnósticas.