[Postoperative analgesia by intrathecal morphine and respiratory depression: value of low doses (apropos of 285 cases)].
Morphine at very low dose gives a good post-operatory analgesia without major secondary effects. This study analyses retrospectively 285 spinal anaesthesia with hyperbaric 0.5% bupivacaine 0.2 mg.kg-1 and morphine 0.25 mg in adult urologic surgery. The analysis of enquiry in analgesic during the post-operatory period shows that in most cases (72%) the patients have supported the first 24 hours without any complementary analgesia; 28% of patients needs a complementary analgesia realized with 1 g of paracetamol. Intravenous morphinics have never been necessary in post-operative period. The analgesia was adequate for the patient's comfort, and it never mask a surgery complication. No respiratory complication appeared, even in 13 patients who needed intravenous morphinics in per-operative.
Koeberle
P
P
Service d'anesthésie-réanimation, Centre hospitalier et universitaire Saint-Jacques, Besançon.
Bourion
P
P
Bettinger
G
G
Barale
F
F
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000698:Analgesia / Q000009:adverse effects / Q000379:methods*; D000775:Anesthesia, Spinal; D002045:Bupivacaine / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage*; D010149:Postoperative Pain / Q000188:drug therapy*; D012131:Respiratory Insufficiency / Q000209:etiology; D012189:Retrospective Studies
D009020:Morphine; D002045:Bupivacaine
Analgésie postopératoire par morphine intrathécale et dépression respiratoire: intérêt des faibles doses (à propos de 285 cas).