[Macrocreatine kinase, a cause of MB isoenzyme levels falsely elevated].
The authors describe two cases of falsely elevated CPK-MB levels due to the presence of a Macro-CPK. The quantification of the mass of CPK-MB gave values lower than the cut-off level. Electrophoresis of CPK isoenzymes showed a type 1 Macro-CPK in one case and a type 2 Macro-CPK in the other. The authors recommend electrophoresis of CPK isoenzymes or quantification of mass if the clinical evolution or ECG changes do not correlate with the CPK-MB levels or if there is a low global CPK with high CPK-MB levels.
Raga
X
X
Laboratoire d'analyses cliniques, hôpital de Sant Pau i Santa Tecla, Tarragona, Espagne.
Vilanova
M A
MA
Bardaji
A
A
Pastor
M R
MR
Richart
C
C
D000368:Aged; D003402:Creatine Kinase / Q000032:analysis*; D003937:Diagnosis, Differential; D004586:Electrophoresis; D005189:False Positive Reactions; D006801:Humans; D007527:Isoenzymes; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis
D007527:Isoenzymes; D003402:Creatine Kinase
Macrocréatine kinase, origine de valeurs faussement élevées d'isoenzyme MB.