Neuropeptide gene expression in transgenic animals.
Transgenic animal techniques offer today's neuroscientist the ability to experimentally manipulate neurosecretory systems with a precision undreamt of by our predecessors. The range of techniques now available, building as it does on our growing knowledge of physiological systems at the inter- and intercellular level, allows us to critically define molecular lesions and ask about their consequences to the whole organism. Neuroscientist should grasp the opportunities afforded by these recent developments.
Murphy
D
D
Neuropeptide Laboratory, National University of Singapore.
Ang
H L
HL
Zeng
Q
Q
Ho
M Y
MY
Funkhouser
J
J
Carter
D
D
D000818:Animals; D030801:Animals, Genetically Modified; D001921:Brain / Q000502:physiology*; D013006:Growth Hormone / Q000096:biosynthesis / Q000235:genetics; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D009474:Neurons / Q000502:physiology*; D009479:Neuropeptides / Q000096:biosynthesis* / Q000235:genetics*; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis
D009479:Neuropeptides; D011993:Recombinant Fusion Proteins; D013006:Growth Hormone