Analysis of association of peptic ulcer and essential hypertension from the standpoint of the problem of concomitant pathology. A possible role of vascular factor in the genesis of ulcer formation.
Patients with association of peptic ulcer and essential hypertension were found to form a heterogeneous group. Examination of this patients' group made it possible to distinguish certain clinical variants of such an association. Patients who first developed essential hypertension and then peptic ulcer were established to have a severe pattern of essential hypertension, unmarked and little symptomatic clinical picture of peptic ulcer, to be characterized by proneness to the complicated disease course. These features together with vascular lesions identified in the gastric submucosal layer, running their course as hypertonic microangiopathies permit attribution of the indicated ulcerations to the group of symptomatic gastroduodenal ulcers. In cases of association of peptic ulcer and essential hypertension, hemiton that suppresses the processes of gastric secretion was found to be the drug of choice.
Grebenev
A L
AL
I.M. Sechenov Moscow Medical Academy, USSR.
Sheptulin
A A
AA
Saltykov
B B
BB
D000328:Adult; D005260:Female; D005753:Gastric Mucosa / Q000098:blood supply*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000150:complications* / Q000209:etiology / Q000473:pathology