Novel flow injection analysis systems for drug analysis.
Flow injection analysis (FIA) has become a versatile tool for rapid and automated analyses. As its capabilities have increased, so have the complexity and operation of the apparatus. We have been investigating ways to simplify both the apparatus and the application of injection techniques. A novel cam-driven syringe pump and the development of sequential injection analysis (SIA) are reviewed, and some applications presented. Flow injection coulometric titrations are presented as a means to further alleviate reagent stability and calibration problems. These systems have potential for automatically carrying out many drug assays.
Christian
G D
GD
Department of Chemistry, University of Washington, Seattle 98195.
D002138:Calibration; D002626:Chemistry, Pharmaceutical / Q000295:instrumentation / Q000379:methods*; D017022:Flow Injection Analysis / Q000295:instrumentation; D004364:Pharmaceutical Preparations / Q000032:analysis*; D017186:Titrimetry
D004364:Pharmaceutical Preparations