title: Syntheses of oligonucleotide derivatives with P(V) porphyrin and their properties.
abstract: Two types of oligonucleotide derivatives which are substituted by P(V) porphyrin at the phosphorus atom of an internucleotidic linkage and at the 5'-terminal internucleotidic linkage via a spacer were synthesized (Fig. 1), and hybridization capabilities of them with complementary oligonucleotides were evaluated. A novel method for a sensing of oligonucleotide by the fluorescence quenching via photo-induced electron transfer between the P(V) porphyrin labeled oligonucleotide and pyrene-labeled one on the oligonucleotide template is reported.
authors.affiliation: Division of Molecular Engineering, Graduate School of Engineering, Kyoto University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Shimidzu
authors.forename: H
authors.initials: H
authors.lastname: Segawa
authors.forename: M
authors.initials: M
authors.lastname: Kitamura
authors.forename: A
authors.initials: A
authors.lastname: Nimura
mesh_terms: D001483:Base Sequence; D004583:Electrons; D005453:Fluorescence; D008969:Molecular Sequence Data; D009841:Oligonucleotides / Q000138:chemical synthesis*; D011166:Porphyrins / Q000737:chemistry*
chemical_list: D009841:Oligonucleotides; D011166:Porphyrins