[Detection of toxoplasma-specific IgA and IgM antibodies in serum samples of adults with acquired toxoplasma infection].
In a study of persons with and without toxoplasmosis, IgA-ISAGA (immunoglobulin A-immunosorbent agglutination assay) was found to be specific. However, serum samples from subjects recently infected wtih toxoplasma were less reliable than the DNR test (IgM-ISAGA by the original method, 1981) and the IgM-IIFT. On the other hand, some serum samples from persons infected for up to a year or longer were IgA-positive. The IgA-ISAGA should therefore not be included in serodiagnosis in pregnancy as a substitute for IgM-ISAGA or IgM-IIFT, but, if at all, in addition to them.
Saathoff
M
M
Institut für Medizinische Parasitologie, Universität Bonn.
Seitz
H M
HM
D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis*; D000918:Antibody Specificity / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000276:immunology
D000913:Antibodies, Protozoan; D007070:Immunoglobulin A; D007075:Immunoglobulin M
Nachweis von toxoplasmaspezifischen IgA- und IgM-Antikörpern in Serumproben von Erwachsenen mit erworbener Toxoplasma-Infektion.