title: Effects of oat bran, rice bran, wheat fiber, and wheat germ on postprandial lipemia in healthy adults.
abstract: Six normolipidemic males ingested on separate days a low-fiber test meal [2.8 g dietary fiber (TDF)] containing 70 g fat and 756 mg cholesterol, enriched or not with 10 g TDF as oat bran, rice bran, or wheat fiber or 4.2 g TDF as wheat germ. Fasting and postmeal blood samples were obtained for 7 h and chylomicrons were isolated. Adding fibers to the test meal induced no change in serum glucose or insulin responses. The serum triglyceride response was lower (P less than or equal to 0.05) in the presence of oat bran, wheat fiber, or wheat germ and chylomicron triglycerides were reduced with wheat fiber. All fiber sources reduced chylomicron cholesterol. Cholesterolemia decreased postprandially for 6 h and was further lowered in the presence of oat bran. Serum apolipoprotein (apo) A-1 and apo B concentrations were not affected. Thus, dietary fibers from cereals may reduce postprandial lipemia in humans to a variable extent.
authors.affiliation: Unité 130-INSERM (National Institute of Health and Medical Research), Marseille, France.
authors.forename: L
authors.initials: L
authors.lastname: Cara
authors.forename: C
authors.initials: C
authors.lastname: Dubois
authors.forename: P
authors.initials: P
authors.lastname: Borel
authors.forename: M
authors.initials: M
authors.lastname: Armand
authors.forename: M
authors.initials: M
authors.lastname: Senft
authors.forename: H
authors.initials: H
authors.lastname: Portugal
authors.forename: A M
authors.initials: AM
authors.lastname: Pauli
authors.forename: P M
authors.initials: PM
authors.lastname: Bernard
authors.forename: D
authors.initials: D
authors.lastname: Lairon
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D002914:Chylomicrons / Q000097:blood; D004043:Dietary Fiber / Q000008:administration & dosage*; D004311:Double-Blind Method; D002523:Edible Grain; D006801:Humans; D007328:Insulin / Q000097:blood; D008055:Lipids / Q000097:blood*; D008297:Male; D012275:Oryza; D011897:Random Allocation; D014280:Triglycerides / Q000097:blood; D014908:Triticum
chemical_list: D001786:Blood Glucose; D002914:Chylomicrons; D004043:Dietary Fiber; D007328:Insulin; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol