[Antiendomysium antibodies in the diagnosis of celiac disease in the adult].
The identification of anti-endomysial antibodies in the serum of coeliac patients has provided a useful diagnostic tool to be used together with biopsy. In this study the presence of these antibodies was evaluated in a population of adult coeliac patients. 92.86% sensitivity and 100% specificity were obtained together with 98.68% diagnostic accuracy. The antibody titer tends to diminish progressively and become negative in patients who adhere strictly to their diet. Anti-endomysial antibodies may therefore be used at both the screening stage as well as during follow-up and they allow an objective assessment of diet compliance to be made.
Sategna-Guidetti
C
C
Dipartimento di Fisiopatologia Clinica, Università degli Studi di Torino.
Pulitanò
R
R
Grosso
S
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D000906:Antibodies / Q000097:blood*; D002446:Celiac Disease / Q000097:blood / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000276:immunology*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
D000906:Antibodies
Gli anticorpi anti-endomisio nella diagnosi di malattia celiaca dell'adulto.