[The release of vasoactive intestinal peptide in patients with dumping syndrome and its clinical significance].
Plasma vasoactive intestinal peptide (VIP), blood glucose concentration and hematocrit (HCT) were measured in 15 patients after Billroth-II subtotal gastrectomy (B-II SG) and 8 healthy controls before and after oral glucose ingestion. In B-II SG group the rate of rise of VIP concentration was in positive correlation to the rate of rise of HCT (r = 0.501 P < 0.05) and to that of blood glucose (r = 0.715 P < 0.01). Also, the elevation rate of HCT blood glucose and VIP concentration was significant higher in B-II SG group than in controls (P < 0.05). It was found that the elevation rate of VIP concentration was much higher in patients with dumping syndrome after B-II SG than those without (P < 0.05). The results suggest that VIP may play a role in the pathogenesis of dumping syndrome.
Yang
H
H
Xin Qiao Hospital, Chongqing.
D001786:Blood Glucose / Q000378:metabolism; D004377:Dumping Syndrome / Q000097:blood* / Q000209:etiology; D005743:Gastrectomy / Q000009:adverse effects; D005947:Glucose / Q000008:administration & dosage; D006400:Hematocrit; D006801:Humans; D008875:Middle Aged; D010437:Peptic Ulcer / Q000601:surgery; D014660:Vasoactive Intestinal Peptide / Q000097:blood*
D001786:Blood Glucose; D014660:Vasoactive Intestinal Peptide; D005947:Glucose