title: Reproductive behaviour and prenatal diagnosis following genetic termination of pregnancy in women of advanced maternal age.
abstract: One hundred and fifty-one women of advanced maternal age who underwent genetic termination of pregnancy (TOP) were studied for their reproductive behaviour and the type of procedure for prenatal diagnosis in a subsequent pregnancy. A total of 59 women (39 per cent) had a further pregnancy. In all continuing pregnancies prenatal diagnosis was performed, of which 75 per cent consisted of chorionic villus sampling (CVS). Reproductive behaviour following a genetic termination was negatively correlated with maternal age and parity. Both reproductive behaviour and the choice to undergo a diagnostic procedure in the next pregnancy were independent of the type of diagnostic procedure in the previous affected pregnancy.
authors.affiliation: Department of Obstetrics and Gynaecology, Academic Hospital Rotterdam-Dijkzigt, Erasmus University, The Netherlands.
authors.forename: H
authors.initials: H
authors.lastname: Brandenburg
authors.forename: W
authors.initials: W
authors.lastname: De Koning
authors.forename: M G
authors.initials: MG
authors.lastname: Jahoda
authors.forename: T
authors.initials: T
authors.lastname: Stijnen
authors.forename: M A
authors.initials: MA
authors.lastname: De Ridder
authors.forename: E S
authors.initials: ES
authors.lastname: Sachs
authors.forename: J W
authors.initials: JW
authors.lastname: Wladimiroff
mesh_terms: D000032:Abortion, Therapeutic; D000328:Adult; D000367:Age Factors; D000649:Amniocentesis; D015193:Chorionic Villi Sampling; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008423:Maternal Age; D010298:Parity; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D011296:Prenatal Diagnosis; D013997:Time Factors