[Hepatic function in circulatory insufficiency. Mathematical modeling of 137I-labelled rose bengal transport in the body].
131I-labelled bengali pink was used to perform radiohepatography in patients with circulatory failure. Both amplitude-time parameters of blood clearance curves and hepatograms and the generalized index of parameters of the linear 3-chambered reversible model of this tracer transport in the body indicate that the decrease of hepatic absorptive and excretory function in the presence of 131I-labelled bengali pink occurs in a direct relationship to the degree of circulatory insufficiency and developed in parallel with bilirubin metabolic disturbances. In some patients, hepatic lesion in the presence of Stages IIB-III circulatory insufficiency with signs of hepatocellular failure and cholestasis was accompanied only by moderate hepatic absorptive and excretory dysfunction against 131I-labelled bengali pink and by an increase in blood total bilirubin levels no more than that in Stage IIA circulatory insufficiency.
Vinogradov
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D001646:Bile / Q000378:metabolism; D001692:Biological Transport; D002303:Cardiac Output, Low / Q000097:blood / Q000378:metabolism*; D006801:Humans; D007457:Iodine Radioisotopes; D008099:Liver / Q000378:metabolism*; D008432:Mathematical Computing; D008954:Models, Biological
D007457:Iodine Radioisotopes
Funktsiia pecheni pri nedostatochnosti krovoobrashcheniia. Matematicheskoe modelirovanie transporta bengal'skogo rozovogo-137I v organizme.