title: Immunosuppression without prophylactic antilymphocyte preparations.
abstract: 1. Triple-drug immunosuppression following third party transfusion can result in graft survival equal to protocols that employ prophylactic antilymphocyte preparations. 2. T1/2 was statistically improved in cadaveric and living-related donor grafts in the CsA era. 3. Patients 65 years and older had an excessive death rate. Younger groups were admixed. Extreme youth was not a risk factor. 4. Black recipients had excessive late graft loss. 5. Diabetic recipients had only a slight decline in graft and patient survival rates. 6. First and multiple graft recipients had similar transplant survival rates. 7. Delayed graft function remains costly in this immunosuppressive scheme.
authors.affiliation: Department of Surgery, University of Florida College of Medicine, Gainesville.
authors.forename: W W
authors.initials: WW
authors.lastname: Pfaff
authors.forename: P R
authors.initials: PR
authors.lastname: Patton
authors.forename: R J
authors.initials: RJ
authors.lastname: Howard
authors.forename: M E
authors.initials: ME
authors.lastname: Brunson
authors.forename: E L
authors.initials: EL
authors.lastname: Ramos
authors.forename: R S
authors.initials: RS
authors.lastname: Fennell
authors.forename: J C
authors.initials: JC
authors.lastname: Peterson
authors.forename: J C
authors.initials: JC
authors.lastname: Scornik
mesh_terms: D000046:Academic Medical Centers; D000328:Adult; D000368:Aged; D000961:Antilymphocyte Serum / Q000627:therapeutic use; D002102:Cadaver; D016572:Cyclosporine / Q000627:therapeutic use; D005431:Florida / Q000453:epidemiology; D006085:Graft Survival; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods*; D016030:Kidney Transplantation / Q000276:immunology* / Q000379:methods* / Q000401:mortality; D008875:Middle Aged; D012307:Risk Factors; D015996:Survival Rate; D014019:Tissue Donors
chemical_list: D000961:Antilymphocyte Serum; D016572:Cyclosporine