title: [The effect of long-term bed-rest head-down-tilt hypokinesia on the functional properties of the human neuromuscular apparatus].
abstract: An influence of 120-days antiorthostatic (-6 degrees) hypokinesia (ANOH) on the functional properties of human m. triceps surae (TS) was investigated. After ANOH the maximal force and the maximal voluntary contraction of TS decreased on the average by 45.5% and 33.7%, respectively, and the maximal twitch response force--by 36.7% (P < 0.05-0.01). The value of force deficit increased on the average by 60.2% (P < 0.001), while a relative increase of the TS force contraction decreased in response to pair irritation (P < 0.05-0.01) as well as the velocity properties of TS after ANOH (P < 0.05-0.001). The rate of absolute (c.u.) tension development fell significantly in response to electrical nerve irritation and during voluntary contraction, while the force-velocity muscle properties according to relative (%) parameters remained unchanged. The fatiguability index of TS constituted the average 0.61 +/- 0.02 after ANOH as against 0.80 +/- 0.03 prior to it (P < 0.05). It is postulated the alterations of contractile properties of TS are due both to atrophic processes, muscle length change, condition of sarcoplasmic reticulum and to changes in the state of the central nervous system.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Koriak
authors.forename: I B
authors.initials: IB
authors.lastname: Kozlovskaia
mesh_terms: D000328:Adult; D001510:Bed Rest; D004558:Electric Stimulation; D006801:Humans; D007103:Immobilization / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction / Q000502:physiology; D009132:Muscles / Q000502:physiology*; D009424:Nervous System Physiological Phenomena; D011187:Posture / Q000502:physiology*; D013979:Tibial Nerve / Q000502:physiology; D013997:Time Factors
vernacular_title: Vliianie dlitel'noĭ postel'noĭ antiortostaticheskoĭ gipokinezii na funktsional'nye svoĭstva nervno-myshechnogo apparata u cheloveka.