title: [Investigation of immunogenic properties of diphtheria antitoxin by intradermal active test of potency].
abstract: Usefulness of four variants of intradermal test for routine testing of protective potency and diphtheria anatoxin was studied. Comparing with classical active test it was found that full intradermal test possesses data system and results comparable to the classic test and may replace it. This in effect results in four-fold reduction of guinea pig number necessary for performance of the investigation. As orientating test, estimate determining AnaDi potency a single dose performed on six guinea pigs was selected. In the intradermal test the time of investigation, as compared with the classic test, may be shortened by one week.
authors.affiliation: Zakład Badania Surowic i Szczepionek PZH w Warszawie.
authors.forename: T
authors.initials: T
authors.lastname: Wysokińska
authors.forename: A
authors.initials: A
authors.lastname: Zakrzewska
mesh_terms: D000818:Animals; D004166:Diphtheria Antitoxin / Q000276:immunology*; D006168:Guinea Pigs; D012882:Skin Tests
chemical_list: D004166:Diphtheria Antitoxin
vernacular_title: Badanie właściwości uodparniajacych anatoksyny błoniczej w śródskórnym teście czynnym mocy.