title: [Surgery and chemotherapy in the treatment of primary gastric lymphomas: case review].
abstract: Fifty-seven patients with primary gastric non-Hodgkin's lymphoma are here reported. All our patients were treated with surgery as first step procedure. Thirty-six were treated in addition with chemotherapy (four of them with radiotherapy also). Thirty-eight were stage IE and nineteen IIE. According to the Working Formulation, 12 cases were classified as low, 25 intermediate and 20 high malignancy. 55 patients achieved a complete remission (96%) and only 6 relapsed (11%). The 10-year disease-related survival is 89%. Patients treated with combined surgery and chemotherapy were mainly a high risk group (high grade histologic subtype, stage IIE, incomplete resection). Nevertheless the survival of this group was similar to the group initially treated with surgery alone (p = 0.17) in which such unfavorable prognostic factors were not present. Stage, presence of residual tumor after surgery, sex and age did not statistically correlate with survival. Furthermore, there was not statistical difference among the various histological subgroups (p = 0.16). We stress the importance of cooperation among surgeons and oncologists in order to plan an appropriate treatment.
authors.affiliation: Istituto di Patologia Speciale Medica, Università di Verona.
authors.forename: F
authors.initials: F
authors.lastname: Pasini
authors.forename: A
authors.initials: A
authors.lastname: Ambrosetti
authors.forename: A
authors.initials: A
authors.lastname: Perini
authors.forename: D
authors.initials: D
authors.lastname: Veneri
authors.forename: R
authors.initials: R
authors.lastname: Sabbioni
authors.forename: G
authors.initials: G
authors.lastname: Todeschini
authors.forename: A
authors.initials: A
authors.lastname: Santo
authors.forename: C
authors.initials: C
authors.lastname: Oliani
authors.forename: G L
authors.initials: GL
authors.lastname: Cetto
mesh_terms: D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008228:Lymphoma, Non-Hodgkin / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011182:Postoperative Care; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D016019:Survival Analysis
vernacular_title: Chirurgia e chemioterapia nel trattamento dei linfomi gastrici primitivi: revisione casistica.