Alpha-fetoprotein production by rhabdomyosarcoma of the urinary bladder.
Alpha-fetoprotein has emerged as a useful diagnostic tool for hepatic tumour and tumours of germ cell origin. However, isolated case reports of association of this tumour marker with tumours of the lung and non-germ cell tumours of the ovary are reported. We present a case of a Rhabdomyosarcoma, a generally non-secretory tumour that showed raised levels of AFP in serum and reacted positively for the same in a PAP technique for AFP. Cross striations were visible in many cells on II & E stained sections.
Badve
S S
SS
Department of Pathology, J.J. Hospital, Bombay, India.
Saxena
R
R
Soman
C S
CS
Kiri
V M
VM
Raghuvanshi
S R
SR
Patoria
N K
NK
D002648:Child; D005260:Female; D006801:Humans; D012208:Rhabdomyosarcoma / Q000378:metabolism*; D001749:Urinary Bladder Neoplasms / Q000378:metabolism*; D000509:alpha-Fetoproteins / Q000096:biosynthesis*
D000509:alpha-Fetoproteins