Multifocal peripheral neuropathy in eosinophilic fasciitis.
Polyneuropathy may complicate eosinophilia-associated connective tissue disease. We report a multi-focal neuropathy in a patient with eosinophilic fasciitis proven by demonstrating an eosinophilic cellular infiltrate in a fascial biopsy specimen from the forearm. Sural nerve biopsy revealed lymphocytic cuffing of epineural arterioles. Although described in the L-tryptophan-related eosinophilia-myalgia syndrome, peripheral neuropathy with these features has not been previously noted in a patient with eosinophilic fasciitis who had not consumed L-tryptophan.
Satsangi
J
J
Department of Clinical Neurology, Radcliffe Infirmary, Oxford, UK.
Donaghy
M
M
D000328:Adult; D001160:Arterioles / Q000473:pathology; D001706:Biopsy; D004802:Eosinophilia / Q000150:complications* / Q000473:pathology; D005205:Fascia / Q000473:pathology; D005208:Fasciitis / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D009132:Muscles / Q000473:pathology; D010523:Peripheral Nervous System Diseases / Q000209:etiology* / Q000473:pathology; D013497:Sural Nerve / Q000098:blood supply / Q000473:pathology