title: [Neuroendocrine giant-cell epithelioma. Description of a clinical case and review of the literature].
abstract: Neuroendocrine tumors are rare neoplasms of the larynx and hypopharynx. This tumors are divided in paragangliomas (usually benign, although malignant case have been reported), large cell neuroendocrine carcinoma, described in this case as a primary pharyngo-laryngeal locate, and small cell neuroendocrine carcinoma (characterized by early and diffuse metastatic disease, and best treated by radiotherapy and chemotherapy). Through the international literature, the authors reviewed the characteristics of the large cell neuroendocrine tumors and their management.
authors.affiliation: Service ORL, Centre Hospitalier Universitaire de Hautepierre, Strasbourg.
authors.forename: C
authors.initials: C
authors.lastname: Debry
authors.forename: N
authors.initials: N
authors.lastname: Rouyer
authors.forename: E
authors.initials: E
authors.lastname: Grandjean
authors.forename: A
authors.initials: A
authors.lastname: Gentine
authors.forename: J L
authors.initials: JL
authors.lastname: Stierle
authors.forename: C
authors.initials: C
authors.lastname: Conraux
mesh_terms: D000368:Aged; D002276:Carcinoid Tumor / Q000473:pathology* / Q000628:therapy; D002277:Carcinoma / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D007150:Immunohistochemistry; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000628:therapy; D008297:Male; D009378:Neoplasms, Multiple Primary; D009490:Neurosecretory Systems; D010235:Paraganglioma / Q000473:pathology* / Q000628:therapy; D010610:Pharyngeal Neoplasms / Q000473:pathology* / Q000628:therapy
vernacular_title: Les épithéliomas neuroendocrines à grandes cellules. Description d'un cas clinique et revue de la littérature.