[The hypolipidemic action of water-soluble enterosorbents of cholesterol and bile acids in an experiment].
Experiments on rats, guinea pigs and rabbits with experimental dyslipoproteinemia have revealed that the new water-soluble high-molecular weight polymers containing digitonin (ED) or a quaternary nitrogen atom (EA) have a more marked hypolipidemic action than cholestyramine and normalize lipoprotein metabolism. The digitonin-containing enterosorbent has been shown to decrease the absorption of 4-14C-cholesterol, while the nitrogen-containing enterosorbent diminishes the absorption of 3H-cholic acid.
Chistiakova
A M
AM
Frolova
Iu V
IuV
Triufanov
V F
VF
Vasil'eva
L E
LE
Lozovskiĭ
V T
VT
Ryzhenkov
V E
VE
D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism*; D002784:Cholesterol / Q000378:metabolism*; D002791:Cholesterol, Dietary / Q000008:administration & dosage; D004072:Digitonin / Q000627:therapeutic use; D016061:Enterosorption / Q000379:methods*; D005069:Evaluation Studies as Topic; D006168:Guinea Pigs; D006937:Hypercholesterolemia / Q000209:etiology / Q000378:metabolism / Q000628:therapy; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D008970:Molecular Weight; D009584:Nitrogen / Q000627:therapeutic use; D011108:Polymers / Q000627:therapeutic use; D011817:Rabbits; D051381:Rats; D012995:Solubility
D001647:Bile Acids and Salts; D002791:Cholesterol, Dietary; D000960:Hypolipidemic Agents; D011108:Polymers; D002784:Cholesterol; D004072:Digitonin; D009584:Nitrogen
Gipolipidemicheskoe deĭstvie vodorastvorimykh énterosorbentov kholesterina i zhelchnykh kislot v éksperimente.