title: [Antibody formation to morphine and neuromediators in morphinized rats].
abstract: The paper demonstrates induction of antibodies to morphine and neurotransmitters (dopamine, norepinephrine, serotonin) in rats treated with intraperitoneal injections of morphine hydrochloride during 2 and 4 weeks in increasing doses. A contribution of such antibodies to the mechanisms of morphine tolerance and formation of physical dependence is considered.
authors.forename: S I
authors.initials: SI
authors.lastname: Tronnikov
authors.forename: N B
authors.initials: NB
authors.lastname: Gamaleia
authors.forename: A G
authors.initials: AG
authors.lastname: Veretinskaia
authors.forename: E V
authors.initials: EV
authors.lastname: Borisova
authors.forename: S K
authors.initials: SK
authors.lastname: Sudakov
authors.forename: I P
authors.initials: IP
authors.lastname: Anokhina
mesh_terms: D000818:Animals; D000906:Antibodies / Q000097:blood; D000917:Antibody Formation / Q000187:drug effects; D015306:Biogenic Monoamines / Q000097:blood / Q000276:immunology*; D002908:Chronic Disease; D008297:Male; D009020:Morphine / Q000008:administration & dosage / Q000276:immunology*; D009021:Morphine Dependence / Q000097:blood / Q000209:etiology / Q000276:immunology*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
chemical_list: D000906:Antibodies; D015306:Biogenic Monoamines; D009020:Morphine
vernacular_title: Obrazovanie antitel k morfinu i neĭromediatoram u morfinizizrovannykh krys.