title: Levels of IgM antibodies against dengue virus in Rio de Janeiro, Brazil.
abstract: The appearance and persistence of IgM antibodies were studied by MAC-ELISA in 926 confirmed cases of dengue virus type 1 infection. Assays performed on acute and convalescent patient sera revealed that IgM antibodies appeared during the early phase of disease (day 2) and persisted for three months after onset. MAC-ELISA proved to be a valuable early diagnosis test when compared with haemagglutination inhibition.
authors.affiliation: Departamento de Virologia, Instituto Oswaldo Cruz, Rio de Janeiro.
authors.forename: R M
authors.initials: RM
authors.lastname: Nogueira
authors.forename: M P
authors.initials: MP
authors.lastname: Miagostovich
authors.forename: S M
authors.initials: SM
authors.lastname: Cavalcanti
authors.forename: K B
authors.initials: KB
authors.lastname: Marzochi
authors.forename: H G
authors.initials: HG
authors.lastname: Schatzmayr
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D001938:Brazil / Q000453:epidemiology; D003715:Dengue / Q000453:epidemiology* / Q000276:immunology; D003716:Dengue Virus / Q000276:immunology*; D004196:Disease Outbreaks; D004797:Enzyme-Linked Immunosorbent Assay; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood* / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M