[Prevention of scar formation by polyglactin 910 (Vicryl) mesh after lumbar laminectomy in the rat].
Laminectomy in lumbar spine surgery often produces disabling adhesive arachnoiditis. We have tested, on the rat, polyglactin 910 mesh with collagen or not, with a mail 0.9 mm large. We have used 34 Wistar male rats. L5 laminectomy were realised on all the rats. Rats were ranged in four groups: group 1: control, L5 laminectomy alone, 6 months follow up--group 2: one month follow up, L5 laminectomy, vicryl mesh with collagen or not--group 3: two months follow up, L5 laminectomy, vicryl mesh with collagen or not--group 4: six months follow up, L5 laminectomy, vicryl mesh with collagen or not. On 28 rats, the histologic study have demonstrated: group 1 control: important and adhesive fibrosis scar--group 2: no or minimal reaction--group 3: fibroblastic or few cellular, non or little adhesive fibrosis--group 4: moderate adhesive fibrosis in half of the cases with vicryl mesh without collagen, minimal non adhesive fibrosis with collagen vicryl mesh.
Griffet
J
J
Chirurgie Orthopédique Infantile, Faculté de Médecine, Hôpital de Cimiez, Nice.
Bastiani
F
F
Hofman
P
P
Argenson
C
C
D000818:Animals; D001100:Arachnoiditis / Q000517:prevention & control*; D005355:Fibrosis / Q000517:prevention & control; D007796:Laminectomy / Q000009:adverse effects*; D008159:Lumbar Vertebrae / Q000601:surgery; D008297:Male; D011098:Polyglactin 910 / Q000627:therapeutic use*; D051381:Rats; D013526:Surgical Mesh
D011098:Polyglactin 910
Prévention de l'épidurite par un treillis de polyglactine 910 (Vicryl) après laminectomie lombaire chez le rat.