title: [Methods for surgical prophylaxis of the development of acute gastroduodenal ulcers].
abstract: The results of the use of prolonged novocaine blockade with the aim of prevention of the development of acute gastroduodenal ulcers in 57 patients are presented. In 21 case, the prolonged blockade of the vagus nerves was used, in 36--that of the ligamentum teres hepatis. After the operation, the proteolytic activity and acidity of gastric juice were studied. All the patients underwent gastroduodenofibroscopy with biopsy and target pH-metry. Under the influence of novocaine blockade, the proteolytic activity decreased, pH increased. At endoscopy, no acute erosive-ulcerous lesion of mucosa was revealed. Thus, a high effectiveness of the use of prolonged novocaine blockade has been proved.
authors.forename: O N
authors.initials: ON
authors.lastname: Skriabin
authors.forename: S E
authors.initials: SE
authors.lastname: Mitin
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004384:Duodenoscopy; D005773:Gastroscopy; D006801:Humans; D008875:Middle Aged; D010437:Peptic Ulcer / Q000175:diagnosis / Q000517:prevention & control*; D011183:Postoperative Complications / Q000175:diagnosis / Q000517:prevention & control*; D011292:Premedication; D011343:Procaine / Q000627:therapeutic use*
chemical_list: D011343:Procaine
vernacular_title: Metody khirurgicheskoĭ profilaktiki obrazovaniia ostrykh gastroduodenalńykh iazv.