title: Bioavailability of methionine-hydroxy-analog free acid and S-methyl-methionine in the growing rat.
abstract: The biological utilization of DL-methionine (MET), DL-methionine-hydroxy-analog and DL-S-methyl-methionine-sulphonium-chloride (SMM) was tested in rat growth assay. Weight gain, feed efficiency, protein efficiency ratio (PER), net protein ratio (NPR) and net protein utilization (NPU) were applied as criteria. A test diet containing soybean meal as sole protein source was fortified with MET, MHA or SMM at 1.5 and 3.0 g/kg levels, respectively. All fortifications had a significant (p < 0.05) positive influence on weight gain, feed conversion and protein utilization. SMM showed the highest activity. MET and MHA were almost equally well utilized at 3.0 g/kg fortification level, however MHA proved slightly less efficient at 1.5 g/kg level than MET.
authors.affiliation: Department of Animal Nutrition, University of Veterinary Science, Budapest, Hungary.
authors.forename: M
authors.initials: M
authors.lastname: Hegedüs
authors.forename: S
authors.initials: S
authors.lastname: Fekete
authors.forename: E
authors.initials: E
authors.lastname: Andrásofszky
authors.forename: J
authors.initials: J
authors.lastname: Tamás
authors.forename: L
authors.initials: L
authors.lastname: Kövári
mesh_terms: D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001682:Biological Availability; D004044:Dietary Proteins / Q000008:administration & dosage; D008297:Male; D008715:Methionine / Q000031:analogs & derivatives* / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar / Q000254:growth & development*
chemical_list: D004044:Dietary Proteins; C008391:alpha-hydroxy-gamma-methylmercaptobutyric acid; D008715:Methionine; C038344:methionine methyl ester