Carbaryl distribution in rabbit tissues and body fluids.
After single po administration of 14C-naphthylcarbamate, liquid scintillation assays evaluated the distribution of carbaryl in rabbit serum, liver, kidneys, small and large intestine, spleen, heart, muscles of the thigh and lungs and its excretion in urine and feces at 2, 4, 6 and 8 h after dosing. At 2 and 8 h radioactivity was not observed in spleen, heart, muscle and lungs, while all other tissues had increased values up to 6 h. The main excretory pathway of carbaryl was the kidneys.
Malvisi
J
J
Instituto di Farmacologia, Farmacocinetica e Tossicologia, Facolta di Medicina Veterinaria, Universita degli Studi di Bologna, Italy.
Zaghini
A
A
Stracciari
G L
GL
D000284:Administration, Oral; D000818:Animals; D001826:Body Fluids / Q000737:chemistry*; D012721:Carbaryl / Q000008:administration & dosage / Q000493:pharmacokinetics*; D002250:Carbon Radioisotopes; D005260:Female; D010573:Pesticide Residues / Q000493:pharmacokinetics; D011817:Rabbits; D014018:Tissue Distribution
D002250:Carbon Radioisotopes; D010573:Pesticide Residues; D012721:Carbaryl