title: Effects of naloxone infusion in patients with septic shock and renal failure: a limited experience.
abstract: Septic shock is frequently associated with acute renal failure. Management of these patients becomes complicated if either the renal or systemic hemodynamic derangement cannot be corrected. Although previously large doses of furosemide and naloxone infusion have been used separately in managing these patients, the combination of both agents has not been employed. We therefore report our limited experience with this combined treatment in 5 patients with septic shock, of which 4 had acute renal failure.
authors.affiliation: Department of Medicine, King Fahad National Guard Hospital, Riyadh, Saudi Arabia.
authors.forename: R R
authors.initials: RR
authors.lastname: Duarte
authors.forename: M M
authors.initials: MM
authors.lastname: Ali
authors.forename: N Y
authors.initials: NY
authors.lastname: Sayegh
authors.forename: P
authors.initials: P
authors.lastname: Nayak
authors.forename: B W
authors.initials: BW
authors.lastname: Grace
mesh_terms: D058186:Acute Kidney Injury / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D000328:Adult; D000368:Aged; D004298:Dopamine / Q000008:administration & dosage; D005260:Female; D005665:Furosemide / Q000008:administration & dosage; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009270:Naloxone / Q000008:administration & dosage*; D012189:Retrospective Studies; D012772:Shock, Septic / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D009270:Naloxone; D005665:Furosemide; D004298:Dopamine