title: [Plasma glycosylated residues demonstrated by proton NMR spectroscopy. Value in the detection of heart graft rejection].
abstract: In conjunction with biopsy and Doppler studies, we analysed by high resolution proton NMR spectroscopy the blood plasma of 22 heart transplant recipients. There was a significant variation in the glycosylated residues of proteins with the development of acute cardiac rejection. A more extensive study is underway to assess the sensitivity and specificity of this approach for the early diagnosis of acute cardiac rejection.
authors.affiliation: Service de Chirurgie Cardiaque, CHU de la Timone, Marseille.
authors.forename: A
authors.initials: A
authors.lastname: Mouly-Bandini
authors.forename: J
authors.initials: J
authors.lastname: Vion-Dury
authors.forename: M
authors.initials: M
authors.lastname: Sciaky
authors.forename: P
authors.initials: P
authors.lastname: Viout
authors.forename: S
authors.initials: S
authors.lastname: Confort-Gouny
authors.forename: T
authors.initials: T
authors.lastname: Mesana
authors.forename: A
authors.initials: A
authors.lastname: Goudard
authors.forename: J R
authors.initials: JR
authors.lastname: Monties
authors.forename: P J
authors.initials: PJ
authors.lastname: Cozzone
mesh_terms: D000117:Acetylglucosamine / Q000097:blood*; D006084:Graft Rejection / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D012794:Sialic Acids / Q000097:blood*
chemical_list: D012794:Sialic Acids; D000117:Acetylglucosamine
vernacular_title: Résidus glycosylés plasmatiques mis en évidence par spectroscopie de RMN du proton. Intérêt dans la détection du rejet de greffe cardiaque.