title: Beta A4 amyloid protein and its precursor in Alzheimer's disease.
abstract: The beta A4 amyloid protein is now understood to play a pivotal role in the development of Alzheimer's disease. This protein is generated by the abnormal processing of the amyloid protein precursor, a large membrane glycoprotein. Insights into the mechanisms of this abnormal processing will give information relevant to the design of new therapeutic strategies for Alzheimer's disease.
authors.affiliation: Department of Pathology, University of Melbourne, Parkville, Australia.
authors.forename: A I
authors.initials: AI
authors.lastname: Bush
authors.forename: K
authors.initials: K
authors.lastname: Beyreuther
authors.forename: C L
authors.initials: CL
authors.lastname: Masters
mesh_terms: D000544:Alzheimer Disease / Q000235:genetics / Q000378:metabolism*; D000595:Amino Acid Sequence; D016229:Amyloid beta-Peptides / Q000235:genetics / Q000502:physiology*; D016564:Amyloid beta-Protein Precursor / Q000502:physiology; D000818:Animals; D006801:Humans; D008969:Molecular Sequence Data
chemical_list: D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor