[Muir-Torre syndrome. Apropos of a case associated with a familial form of cancer].
We report the case of 41 year-old male patient, in whom multiple and recurrent infrequent cutaneous lesions (sebaceous adenomas) led to suspect the diagnosis of Muir-Torre syndrome. This diagnosis was confirmed when 2 colo-rectal adenocarcinomas were discovered and curatively excised (trans-anal excision, followed by total colectomy). The Muir-Torre syndrome was part of a familial cancer syndrome in this case, as the patient's mother and brother died from colonic cancer before the age of 45. The case-report underlines the diagnostic role of cutaneous lesions in this syndrome, allowing early detection of internal malignancy.
Prunet
D
D
Clinique Chirurgicale II, Hôpital Laënnec, Nantes.
Lehur
P A
PA
Guiberteau-Canfrère
V
V
Thébaud
Y
Y
Litoux
P
P
Le Borgne
J
J
D000230:Adenocarcinoma / Q000150:complications* / Q000235:genetics / Q000601:surgery; D000236:Adenoma / Q000150:complications* / Q000601:surgery; D000328:Adult; D003082:Colectomy; D015179:Colorectal Neoplasms / Q000150:complications* / Q000235:genetics / Q000601:surgery; D006801:Humans; D008297:Male; D012626:Sebaceous Gland Neoplasms / Q000150:complications* / Q000601:surgery; D013577:Syndrome
Syndrome de Torre et Muir. Rapport d'un cas associé à un syndrome de cancer familial.