[The effect of ascitic fluid globulins on the growth of leukemia P388/DOX and Ehrlich's carcinoma in mice].
The study was performed to investigate the effect of ascitic fluid globulins of tumor on tumor growth and life span of mice. The globulins are shown to shorten the life span of Ehrlich tumor mice from 86.8 to 61.8 days, to increase 3-5-fold the growth rate of Ehrlich carcinoma and P388/DOX tumor. It was found that globulins of ascitic fluids and serum globulins of tumor have equal effects of tumor growth. It is proposed to use globulins of ascitic fluid to study the globulin role in tumor growth.
Donenko
F V
FV
Kabieva
A O
AO
Moroz
L V
LV
D000818:Animals; D001202:Ascitic Fluid / Q000503:physiopathology*; D002286:Carcinoma, Ehrlich Tumor / Q000097:blood / Q000401:mortality / Q000503:physiopathology*; D005916:Globulins / Q000302:isolation & purification / Q000494:pharmacology*; D007941:Leukemia P388 / Q000097:blood / Q000401:mortality / Q000503:physiopathology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008811:Mice, Inbred DBA; D009368:Neoplasm Transplantation; D012712:Serum Globulins / Q000302:isolation & purification / Q000494:pharmacology; D013997:Time Factors
D005916:Globulins; D012712:Serum Globulins
Vliianie globulinov astsitnoĭ zhidkosti na rost leĭkoza P388/DKS i kartsinomy Erlikha u mysheĭ.