[Mibelli's porokeratosis after bone marrow transplantation].
A 24-year old male patient developed, on both legs, lesions typical of Mibelli's porokeratosis 22 months after bone marrow transplantation, under treatment with cyclosporin A. He denied any family history. Mibelli's porokeratosis seldom develops after an immunosuppressive treatment, and to our knowledge it has exceptionally been described after bone marrow transplantation. A possible complication of Mibelli's porokeratosis is the development of Bowen's disease, basal or squamous cell carcinomas. Immunosuppressive treatment might facilitate the degeneration. For this reason, these subjects should be periodically and carefully examined.
Ghigliotti
G
G
Division de Dermatologie, Hôpital S. Martino, Gênes, Italie.
Nigro
A
A
Gambini
C
C
Farris
A
A
Burroni
A
A
de Marchi
R
R
D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D016572:Cyclosporine / Q000009:adverse effects; D006087:Graft vs Host Reaction; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D007945:Leukemia, Lymphoid / Q000628:therapy; D008297:Male; D017499:Porokeratosis / Q000209:etiology* / Q000473:pathology
D016572:Cyclosporine
Porokératose de Mibelli après une greffe de moelle.