Comparative evaluation of HIV infected foreign students and Indian with AIDS in Chandigarh, India.
Out of a total of 1,600 foreign students who came to India between June 1989 and October 1990, 22 were seropositive for HIV-1. Ten showed antibodies to all the gene products. Antibodies to gp160 and p24 were present in all the seropositives while antibodies to p53, p15/17 were significantly higher in healthy seropositives than in patients with full blown AIDS. Absence of antibodies to p15/17 and p53 thus appeared to be a more sensitive criterion of end stage disease than absence of anti- p24 antibodies. When seropositive samples from African students were checked for HIV-2 antibodies by ELISA, 13/22 were found to be positive. Further, 2/10 Indians with full blown AIDS were also strongly positive for HIV-2. These data could be of relevance for formulating future strategies for population-based screening for HIV-2.
Sehgal
S
S
Department of Immunopathology Postgraduate Institute of Medical Education and Research, Chandigarh, India.
D000163:Acquired Immunodeficiency Syndrome / Q000208:ethnology / Q000276:immunology*; D000293:Adolescent; D000328:Adult; D000349:Africa / Q000208:ethnology; D015153:Blotting, Western; D004797:Enzyme-Linked Immunosorbent Assay; D005069:Evaluation Studies as Topic; D005260:Female; D015483:HIV Antibodies / Q000032:analysis; D015658:HIV Infections / Q000208:ethnology / Q000276:immunology*; D006679:HIV Seropositivity / Q000208:ethnology / Q000276:immunology; D015497:HIV-1 / Q000276:immunology*; D015498:HIV-2 / Q000276:immunology*; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D013334:Students
D015483:HIV Antibodies