[The effect of hydrocortisone on the alkaline proteinase activity in the target organs of rats].
The effect of hydrocortisone on the thymus and liver proteinases activity in the alkaline pH range was studied on rats. It is shown that the alkaline proteinases are activated in the thymus and inhibited in the liver of hormone-treated animals. Possible relationship between the effect of glucocorticoids on protein metabolism and alkaline proteinases activity is suggested.
Sergeev
P V
PV
Ogurtsov
S I
SI
Dukhanin
A S
AS
Mitroshina
S Iu
SIu
D000818:Animals; D004305:Dose-Response Relationship, Drug; D010450:Endopeptidases / Q000187:drug effects* / Q000378:metabolism; D006854:Hydrocortisone / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D051381:Rats; D013950:Thymus Gland / Q000187:drug effects* / Q000201:enzymology
D010450:Endopeptidases; D006854:Hydrocortisone
Vliianie gidrokortizona na aktivnost' shchelochnykh proteinaz v organakh-misheniakh krys.