[Progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of a case and review of the literature].
Progressive supranuclear palsy (PSP) was first recognized as a distinct syndrome by Richardson, Steele and Olszewski roughly a quarter century ago. Subsequent clinical experience has corroborated and enlarged their original observations. PSP has become familiar as a chronic progressive disorder with extrapyramidal rigity, bradykinesia, gait impairment, bulbar palsy, dementia and a characteristic supranuclear ophthalmoplegia. It is a significant cause of parkinsonism and its etiology remains obscure. The case of a patient from Santa Catarina who presented definite clinical evidences of this syndrome is reported. This is the first description in this southern Brazilian State, where at least 50 more patients should exist, if we may extrapolate the prevalence rate of this condition in developed countries to this well developed area of Brazil. A review of the literature was undertaken with emphasis on recent clinical and therapeutic aspects of PSP.
Trevisol-Bittencourt
P C
PC
Departamento de Clínica Médica, Universidade Federal de Santa Catarina (UFSC), Brasil.
D000368:Aged; D006801:Humans; D008297:Male; D013494:Supranuclear Palsy, Progressive / Q000175:diagnosis* / Q000188:drug therapy
Paralisia supranuclear progressiva. (Sindrome de Steele-Richardson-Olszewski) apresentação de caso e revisão da literatura.