[The protective role of estradiol under extreme conditions].
It has been demonstrated that estradiol increases the resistance of the animals to hemorrhagic shock. Apparently, it is accounted for by its positive effect on cardiovascular system (by stimulation of myocardial contractility, stabilization of ATP and CF pools, inhibition of lipid peroxidation and lysosomal enzymes, etc.).
Matiushin
A I
AI
D000208:Acute Disease; D000818:Animals; D002319:Cardiovascular System / Q000187:drug effects / Q000503:physiopathology; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D004734:Energy Metabolism / Q000187:drug effects; D004958:Estradiol / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D012727:Sex Characteristics; D012771:Shock, Hemorrhagic / Q000188:drug therapy* / Q000401:mortality / Q000503:physiopathology; D012995:Solubility
D004958:Estradiol
Zashchitnaia rol' éstradiola pri ékstremal'nykh sostoianiiakh.