Decreased superoxide dismutase activity in erythrocyte in Parkinson's disease.
Superoxide dismutase (SOD) activities in Parkinson's disease (PD) were significantly lower than those in controls, especially in a treated PD group. However, SOD activities in an untreated PD group did not decrease. There was a significant correlation between SOD activities and the duration of illness in the treated PD group (p < 0.05). There was a significant correlation between SOD activities and the present doses of L-DOPA/carbidopa in the treated PD group.
Urakami
K
K
Division of Neurology, Faculty of Medicine, Tottori University, Yonago, Japan.
Sano
K
K
Matsushima
E
E
Okada
A
A
Saito
H
H
Takahashi
K
K
Ikebuchi
J
J
Mura
T
T
Ikawa
S
S
D000368:Aged; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000201:enzymology*; D013482:Superoxide Dismutase / Q000097:blood*
D013482:Superoxide Dismutase