In vitro solubility of human pulp tissue in calcium hydroxide and sodium hypochlorite.
The tissue solvent capacity of a 2% stabilized sodium hypochlorite solution (Milton) and a commercial calcium hydroxide solution (Calasept) was examined under in vitro conditions where autolyzed human pulp fragments weighing approximately 0.0065 g were immersed in these solutions at 37 degrees C for periods of up to 10 days. It appeared that sodium hypochlorite was able to dissolve half the volume of pulp tissue within 1 h and the remaining tissue after 2-2 1/2 h. Calcium hydroxide dissolved half the pulp volume within 2 h, whereas it took 1 week for the remaining tissue to dissolve. These findings support the use of sodium hypochlorite as an irrigation solution during canal preparation and calcium hydroxide as a canal dressing for the purpose of creating a canal free of pulp remnants before root filling.
Andersen
M
M
Royal Dental College, Copenhagen, Denmark.
Lund
A
A
Andreasen
J O
JO
Andreasen
F M
FM
D002126:Calcium Hydroxide / Q000494:pharmacology*; D003782:Dental Pulp / Q000187:drug effects*; D006801:Humans; D012388:Root Canal Irrigants / Q000494:pharmacology; D012973:Sodium Hypochlorite / Q000494:pharmacology*; D012995:Solubility
D012388:Root Canal Irrigants; D012973:Sodium Hypochlorite; D002126:Calcium Hydroxide