An evaluation of analyzed data of hemoglobin derivatives by CO-Oximeter in medico-legal autopsy.
We examined blood samples of autopsy cases by a CO-Oximeter and evaluated the data for investigation of death including asphyxia. When sampling methods were examined, oxyhemoglobin (O2-Hb) concentrations increased, and reduced hemoglobin (R-Hb) concentrations decreased, by the contact of the blood with the air, while carboxyhemoglobin (CO-Hb) and methemoglobin (Met-Hb) concentrations appeared to be unchanged. The CO-Hb concentrations in the left heart blood were higher than those of the right. In the cases of death due to cold exposure, O2-Hb concentrations of the left heart blood were prominently higher than those of the right. In the cases of death in house fires and the asphyxiated, O2-Hb concentrations were extremely low (below 10%) in both of the left and right heart blood.
Higuchi
T
T
Department of Legal Medicine, Osaka City University Medical School, Japan.
Noguchi
K
K
Maeda
H
H
D001237:Asphyxia / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D002263:Carboxyhemoglobin / Q000032:analysis; D002423:Cause of Death; D005390:Fires; D005554:Forensic Medicine; D006321:Heart; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D007035:Hypothermia; D008706:Methemoglobin / Q000032:analysis; D010092:Oximetry; D010108:Oxyhemoglobins / Q000032:analysis
D006454:Hemoglobins; D010108:Oxyhemoglobins; D008706:Methemoglobin; D002263:Carboxyhemoglobin