Long term morbidity and mortality after kidney transplantation.
A cohort of 69 patients received a kidney transplant in the period 1963-1977. The mean observation time was 9.5 years. Accumulated follow-up time was 661.4 patients year. The mean (SE) 10-year survival was 55(5.9)%. Univariate analysis showed that female patients had poorer survival than male. Patients with a cadaveric donor had lower survival than those with a living donor. Also survival with different HLA-A,B match differed significantly. A multivariate analysis pinpointed nature of donor, cadaveric vs. living, as the sole independent predictor of mortality. Patients receiving a cadaveric kidney were on double (2.2) relative risk of mortality as compared to patients with a living donor. The major causes of death were infections during rejection treatment, and cardiovascular disease. Patients had low rates of morbidity. Our results showed satisfactory outcome of kidney transplantation.
Gorlén
T
T
Department of Nephrology, Ullevål Hospital, Oslo, Norway.
Abdelnoor
M
M
Enger
E
E
Halvorsen
S
S
Leivestad
T
T
Malm
O J
OJ
Aarseth
H P
HP
D000293:Adolescent; D000328:Adult; D000368:Aged; D002102:Cadaver; D002423:Cause of Death; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007676:Kidney Failure, Chronic / Q000401:mortality / Q000601:surgery*; D016030:Kidney Transplantation / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality*; D016016:Proportional Hazards Models; D012086:Reoperation; D012307:Risk Factors; D015996:Survival Rate