title: [A current update on the etiopathogenesis of palatoschisis].
abstract: By means of a review of the most recent literature, the authors report on "state of the art" about etiology and pathogenesis of cleft palate. Epithelial-mesenchymal interactions regulating growth and orientation of palatal shelves, as well as teratogenic effects on such ultrastructural development control by endogenous and exogenous substances, are described.
authors.affiliation: Facoltà di Medicina e Chirurgia, Istituto di Odonto-Gnato-Stomatologia, Università degli Studi di Firenze.
authors.forename: P
authors.initials: P
authors.lastname: Pierleoni
authors.forename: I
authors.initials: I
authors.lastname: Tollaro
authors.forename: T
authors.initials: T
authors.lastname: Baccetti
authors.forename: L
authors.initials: L
authors.lastname: Franchi
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000196:embryology / Q000209:etiology / Q000378:metabolism; D000818:Animals; D002972:Cleft Palate / Q000196:embryology / Q000209:etiology* / Q000378:metabolism; D005938:Glucocorticoids / Q000633:toxicity; D006801:Humans; D010159:Palate / Q000196:embryology / Q000378:metabolism; D014801:Vitamin A / Q000633:toxicity
chemical_list: D005938:Glucocorticoids; D014801:Vitamin A
vernacular_title: Attuali orientamenti sulla etiopatogenesi della palatoschisi.