title: Hashimoto's thyroiditis in HTLV-I carriers.
abstract: We describe two HTLV-I virus carriers who have biopsy-proven Hashimoto's thyroiditis. The first patient, a 64-year-old female, has had goiter and hypothyroidism since the age of 56. The second patient, a 66-year-old male, developed hyperthyroidism and goiter at the age of 44, but at present he is hypothyroid. Both patients are positive for anti-thyroid antibodies and anti-HTLV-I virus antibody. Findings of the thyroid biopsy specimens were consistent with Hashimoto's thyroiditis. These data suggest that Hashimoto's thyroiditis develops in HTLV-I carriers who have no clinical evidence of HAM/TSP.
authors.affiliation: First Department of Internal Medicine, School of Medicine, University of Tokushima, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kawai
authors.forename: M
authors.initials: M
authors.lastname: Saito
authors.forename: M
authors.initials: M
authors.lastname: Takagi
authors.forename: T
authors.initials: T
authors.lastname: Tsuchihashi
authors.forename: Y
authors.initials: Y
authors.lastname: Arii
authors.forename: A
authors.initials: A
authors.lastname: Kondo
authors.forename: M
authors.initials: M
authors.lastname: Iwasa
authors.forename: T
authors.initials: T
authors.lastname: Hirose
authors.forename: K
authors.initials: K
authors.lastname: Hizawa
authors.forename: S
authors.initials: S
authors.lastname: Saito
mesh_terms: D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis; D015139:Blotting, Southern; D002353:Carrier State; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D015368:Human T-lymphotropic virus 1 / Q000235:genetics / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D013961:Thyroid Gland / Q000276:immunology / Q000473:pathology; D013963:Thyroid Hormones / Q000032:analysis; D013967:Thyroiditis, Autoimmune / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology*
chemical_list: D000914:Antibodies, Viral; D004279:DNA, Viral; D013963:Thyroid Hormones