title: Repair of retinitis-related retinal detachments with silicone oil in patients with acquired immunodeficiency syndrome.
abstract: To provide prompt visual rehabilitation and to reduce the need for repeated operations, we performed vitrectomy with silicone oil tamponade in 16 consecutive eyes with retinal detachments related to cytomegalovirus retinitis and acute retinal necrosis in 13 patients with acquired immunodeficiency syndrome. In all 16 eyes (100%), retinas were reattached with one operation. Preservation of ambulatory vision was achieved in six of eight eyes (75%; mean follow-up, 14.6 weeks). No patient with hand motion visual acuity or worse preoperatively recovered ambulatory vision. Visual acuity recovery was limited by optic nerve disease in five eyes (31%). Silicone oil-related side effects did not adversely affect visual outcome in any eye. Six patients (46%) have since died (mean, 4.4 months postoperatively). These data indicated that successful surgical repair of these detachments can be consistently achieved with this approach. The prognosis for ambulatory vision is strongly related to preoperative visual acuity.
authors.affiliation: Retina Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.
authors.forename: C D
authors.initials: CD
authors.lastname: Regillo
authors.forename: J F
authors.initials: JF
authors.lastname: Vander
authors.forename: J S
authors.initials: JS
authors.lastname: Duker
authors.forename: D H
authors.initials: DH
authors.lastname: Fischer
authors.forename: J B
authors.initials: JB
authors.lastname: Belmont
authors.forename: R
authors.initials: R
authors.lastname: Kleiner
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D003586:Cytomegalovirus Infections / Q000150:complications*; D015828:Eye Infections, Viral / Q000150:complications*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012163:Retinal Detachment / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D012173:Retinitis / Q000150:complications* / Q000188:drug therapy; D012827:Silicone Oils / Q000627:therapeutic use*; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy
chemical_list: D012827:Silicone Oils