Mathematical modelling of the elastic properties of retina: a determination of Young's modulus.
The retina can be regarded as an elastic membrane or sheet which stretches and deforms when a force is applied to it. Isolated bovine retina was taken and a graded traction force applied to determine retinal profile as a function of force. The resulting profile can be modelled mathematically and the model then used to determine a value for the elastic constant. The value of the elastic constant obtained by this method is approximately 2 N/m. This value of the elastic constant, combined with the observed retinal thickness, yields a value of Young's modulus for retina of approximately 2 x 10(4) Pa, which is about 2 orders of magnitude weaker than typical rubber. This value can then be used in modelling retinal behaviour in vivo when forces are applied to detached retina.
Jones
I L
IL
Cavendish Laboratory, Cambridge, UK.
Warner
M
M
Stevens
J D
JD
D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D002417:Cattle; D004548:Elasticity; D008954:Models, Biological; D008962:Models, Theoretical; D012160:Retina / Q000502:physiology*