title: Genetic control of bone remodeling.
abstract: Biological research related to orthodontics naturally leads to two general areas. One is the investigation of craniofacial growth and development in normal and abnormal circumstances, attempting to understand the etiological basis for the development of malocclusion or dentofacial deformity. The other concerns developing an understanding of the basic mechanisms involved in tooth movement during orthodontic therapy. This paper reviews ongoing research in both areas.
authors.affiliation: USC School of Dentistry, Los Angeles, CA 90089.
authors.forename: J H
authors.initials: JH
authors.lastname: Zernik
authors.forename: C
authors.initials: C
authors.lastname: Minken
mesh_terms: D000469:Alkaline Phosphatase / Q000235:genetics; D000539:Alveolar Process / Q000254:growth & development; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D016723:Bone Remodeling / Q000235:genetics*; D002648:Child; D015971:Gene Expression Regulation, Enzymologic; D006801:Humans; D008297:Male; D008334:Mandible; D008407:Mast Cells / Q000502:physiology; D051379:Mice; D008969:Molecular Sequence Data; D009971:Orthodontics, Corrective; D010010:Osteoclasts; D010375:Pedigree; D011378:Prognathism / Q000235:genetics*
chemical_list: D000469:Alkaline Phosphatase