title: [Bovine costal cartilage as material for otologic reconstruction: anatomo-functional results].
abstract: The Authors present their experience in using bovine cartilage as otological material reconstruction. Cartilage of the ribs is to collect from selected bred cattle and is first placed in an antibiotic solution for 3 days and then in a 70% ethyl alcohol in which it is stored for 20 days before being utilized. One hundred-nineteen cartilage heterografts have been implanted in the middle ear since January 1989. We report the results of 86 cases which were included in a followed study for at least 12 months. Bovine cartilage was used in 47 canal up techniques, 28 canal down techniques and 11 anatomic and functional rehabilitation of old radical cavities. The result prove most encouraging. In 74 cases we observed good anatomical results characterized by a new, intact eardrum with no sign of inflammation or a cavity lined with normal epithelium. No extrusion was found. Removal of cartilage implanted after a year enabled us observe the high tolerance of the graft and to carry out further histological examination. The histological findings indicated normal and intact cartilagineous matrix, lined with fibrous tissue and mucosa with no evidence of condrocytes. In cases in which the heterografts were utilized for ossiculoplasty, the post-operative air-bone gap was 11.1 dB and the mean hearing gain was 26.3 dB. Moreover, bovine cartilage is easily obtainable and available in pieces of sizes necessary for specific purposes in otologic surgery. Cartilage heterografts might well be a good alternative to autologous and homologous cartilage grafts.
authors.affiliation: Istituto di Clinica Otorinolaringoiatrica, Università di Pisa.
authors.forename: P
authors.initials: P
authors.lastname: Bruschini
authors.forename: G
authors.initials: G
authors.lastname: Segnini
authors.forename: P
authors.initials: P
authors.lastname: Viacava
authors.forename: S
authors.initials: S
authors.lastname: Berrettini
authors.forename: S
authors.initials: S
authors.lastname: Sellari Franceschini
authors.forename: S
authors.initials: S
authors.lastname: Bottoni
authors.forename: F
authors.initials: F
authors.lastname: Piragine
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002356:Cartilage / Q000637:transplantation*; D002417:Cattle; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012272:Ribs; D014021:Tissue Preservation; D014183:Transplantation, Heterologous; D014433:Tympanoplasty / Q000379:methods
vernacular_title: La cartilagine costale bovina come materiale di ricostruzione in otologia: risultati anatomo-funzionali.