title: [Experimental perilymphatic fistula: the electrocochleographic findings].
abstract: The aim of the present study was to evaluate the effect of experimental perilymphatic fistula on cochlear electrophysiological responses. Six albino guinea pigs, in which recording electrodes were implanted in order to record the electrocochleogram, were used. Experimental protocol investigated cochlear responses before the induction of the fistula in the round window membrane perforation and then two month later. Compound action potential thresholds increased immediately after perforation of the round window membrane. The thresholds rapidly recovered. This phenomenon was accompanied by clear-Out reduction in amplitude upon suprathreshold stimulation. This latter observation associated with a decrease in the amplitude of the threshold seems to be a specific audiologic sign of the fistula. The clinical implication are discussed.
authors.affiliation: IV Clinica Otorinolaringoiatrica, Università La Sapienza, Roma.
authors.forename: G
authors.initials: G
authors.lastname: Magliulo
authors.forename: R
authors.initials: R
authors.lastname: Petti
authors.forename: G M
authors.initials: GM
authors.lastname: Vingolo
authors.forename: R
authors.initials: R
authors.lastname: Ronzoni
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000818:Animals; D003052:Cochlear Aqueduct / Q000503:physiopathology*; D015834:Cochlear Diseases / Q000503:physiopathology*; D003055:Cochlear Microphonic Potentials / Q000502:physiology*; D004195:Disease Models, Animal; D004566:Electrodes; D005402:Fistula / Q000503:physiopathology*; D006168:Guinea Pigs; D012405:Round Window, Ear / Q000503:physiopathology; D013997:Time Factors
vernacular_title: Fistola perilinfatica sperimentale: rilievi elettrococleografici.