title: [The biological mechanisms of a congenital predisposition to alcoholism].
abstract: In descendants of white rats with chronic alcoholic intoxication, the contents of DA in the brain and blood plasma, characteristics of GABA and opiate brain receptors, the contents of cAMP and other substances were studied as well as the c-fos gene expression. The data obtained suggest a considerable role of the changes in the DA system functions in the genesis of pathology in these descendants.
authors.forename: I P
authors.initials: IP
authors.lastname: Anokhina
authors.forename: N L
authors.initials: NL
authors.lastname: Vekshina
authors.forename: M N
authors.initials: MN
authors.lastname: Kuznetsova
authors.forename: L N
authors.initials: LN
authors.lastname: Ovchinnikova
authors.forename: A V
authors.initials: AV
authors.lastname: Stanishevskaia
authors.forename: N A
authors.initials: NA
authors.lastname: Khristoliubova
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Shamakina
mesh_terms: D000437:Alcoholism / Q000235:genetics / Q000503:physiopathology*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D001923:Brain Chemistry / Q000187:drug effects; D004198:Disease Susceptibility / Q000151:congenital / Q000503:physiopathology; D000431:Ethanol / Q000494:pharmacology; D005260:Female; D005786:Gene Expression Regulation / Q000187:drug effects / Q000502:physiology; D016762:Genes, fos / Q000187:drug effects / Q000502:physiology; D020022:Genetic Predisposition to Disease; D008297:Male; D051381:Rats
chemical_list: D000431:Ethanol
vernacular_title: Nekotorye biologicheskie mekhanizmy vrozhdennoĭ predraspolozhennosti k alkogolizmu.