Antiepileptic drugs in pregnancy: late effects on the children's cognitive abilities. Preliminary data.
The authors report preliminary data on cognitive development of 57 children, perspectively followed, who were exposed to antiepileptic drugs in utero for maternal epilepsy. Cognitive impairments are associated with other risk factors in 5 cases, so that a direct AEDs responsibility is not easy to prove.
Perniola
T
T
Neurological Clinic, University of Bari, Italy.
Buttiglione
M
M
Margari
L
L
D000927:Anticonvulsants / Q000009:adverse effects*; D002675:Child, Preschool; D003072:Cognition Disorders / Q000139:chemically induced*; D004827:Epilepsy / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D011297:Prenatal Exposure Delayed Effects; D011596:Psychomotor Disorders / Q000139:chemically induced*
D000927:Anticonvulsants