title: [The comparative characteristics of the biological and immunomodulating activities of enzyme preparations of microbial origin].
abstract: A number of enzyme preparations of microbial origin such as immunomodulators and immunostimulators have been studied in vitro according to reactions of rosette technique of cell (ROC) active and general, adhesion, activation of a complement and also the spontaneous activity and phagocytosis of neutrophils have been determined. The enzyme preparations of microbial origin have been shown to be capable of causing immunomodulation and of influencing the specific and nonspecific immune response. Unlike the enzymes of animal origin the enzymes of microbial origin are effective in smaller concentrations. The studied preparations modulate the immune response differently according to ROC, adhesion. Each of preparations has specific features of biological activity--bacterio-stationary in reaction to a certain group of microorganisms and some specific features of reaction with cell and levels of immune reactions.
authors.forename: N A
authors.initials: NA
authors.lastname: Dobrotina
authors.forename: G P
authors.initials: GP
authors.lastname: Ezhova
authors.forename: Zh A
authors.initials: ZhA
authors.lastname: Kazatskaia
authors.forename: G N
authors.initials: GN
authors.lastname: Ladygina
authors.forename: M V
authors.initials: MV
authors.lastname: Kurova
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D001412:Bacillus subtilis / Q000201:enzymology; D001419:Bacteria / Q000201:enzymology*; D003167:Complement Activation / Q000187:drug effects; D004798:Enzymes / Q000494:pharmacology*; D008163:Luminescent Measurements; D009504:Neutrophils / Q000187:drug effects; D016897:Respiratory Burst / Q000187:drug effects; D012397:Rosette Formation; D012706:Serratia marcescens / Q000201:enzymology; D013302:Streptomyces / Q000201:enzymology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D004798:Enzymes
vernacular_title: Sravnitel'naia kharakteristika biologicheskoĭ i immunomoduliruiushcheĭ aktivnosti nekotorykh fermentnykh preparatov mikrobnogo proiskhozhdeniia.