[The immunomodulating properties of the diuretic bufenoks].
Bufenox, a diuretic with a sodium-uretic and light potassium--uretic effect, has an immediate but short-term effect, stimulates IgM antibody production, depressed delayed-type hypersensitivity. The immunomodulating effect of bufenox may be due to changes in Na+ ions concentrations since sodium load abrogates immunoactive properties of the drug.
Romanova
T V
TV
Prokina
V V
VV
Kolesnikova
O P
OP
Kudaeva
O T
OT
Kozlov
V A
VA
D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D000921:Antibody-Producing Cells / Q000187:drug effects / Q000276:immunology; D002034:Bumetanide / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D006968:Hypersensitivity, Delayed / Q000139:chemically induced / Q000276:immunology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009318:Natriuresis / Q000187:drug effects / Q000276:immunology; D011188:Potassium / Q000652:urine; D013154:Spleen / Q000187:drug effects / Q000276:immunology
D000276:Adjuvants, Immunologic; D002034:Bumetanide; D011188:Potassium
Immunomoduliruiushchie svoĭstva diuretika bufenoksa.