title: [The geographical distribution of genetic variants of the tick-borne encephalitis virus].
abstract: Geographic distribution of 185 tick-borne encephalitis (TBE) virus strains isolated in 8 physico-geographic areas and classified into six genetic variants was analysed. The strains of genetic variant I homologous to the Sophyin prototype strain were found to occur predominantly in the Far East and also frequently found in Western and North-Western parts of the East European plain. The vast territories from lake Baikal in the East to Ukraine in the West harbor mostly the strains significantly different from the Far-Eastern Sophyin strain. Hybridization experiments with oligonucleotide probes specific for the Neudorffle strain showed that the strains genetically similar to the virus of central European encephalitis occurred also in Eastern Europe and Western Siberia. It is concluded that a relationship exists between genetic types of TBE virus and their geographic origin.
authors.forename: V I
authors.initials: VI
authors.lastname: Zlobin
authors.forename: V A
authors.initials: VA
authors.lastname: Shamanin
authors.forename: D A
authors.initials: DA
authors.lastname: Drokin
authors.forename: Iu P
authors.initials: IuP
authors.lastname: Dzhioev
authors.forename: I V
authors.initials: IV
authors.lastname: Voronko
authors.forename: O V
authors.initials: OV
authors.lastname: Mel'nikova
authors.forename: N A
authors.initials: NA
authors.lastname: Gusarova
authors.forename: T V
authors.initials: TV
authors.lastname: Vikhoreva
authors.forename: I V
authors.initials: IV
authors.lastname: Kozlova
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D004247:DNA / Q000235:genetics; D015342:DNA Probes / Q000235:genetics; D004279:DNA, Viral / Q000235:genetics; D004197:Disease Reservoirs; D004669:Encephalitis Viruses, Tick-Borne / Q000235:genetics* / Q000302:isolation & purification; D014644:Genetic Variation / Q000235:genetics*; D016679:Genome, Viral; D051379:Mice; D015345:Oligonucleotide Probes / Q000235:genetics; D012367:RNA, Viral / Q000235:genetics; D012426:Russia; D013987:Ticks / Q000382:microbiology
chemical_list: D015342:DNA Probes; D004279:DNA, Viral; D015345:Oligonucleotide Probes; D012367:RNA, Viral; D004247:DNA
vernacular_title: Geograficheskoe rasprostranenie geneticheskikh variantov virusa kleshchevogo éntsefalita.