[Pancreatic beta cells and cytokines].
Over the past decade the study of Interleukins and Interferons has advanced from functional descriptions to detailed structural understanding. The ability of these growth factors to act, directly or through immune mechanisms on the pancreatic beta-cell and to affect in vitro and in vivo both its morphology and physiology, indicate that they may play a role in the pathogenesis and prevention of insulin-dependent diabetes mellitus. Also, the relation between these cytokines-constitutive or upon stimulation maybe useful to predict the development of diabetes mellitus.
Aguilar Parada
E
E
Laboratorio de Patología Experimental, Centro Médico Nacional Siglo XXI, IMSS.
Rábago Velasco
M
M
García Vela
E
E
Ramos Avila
R
R
Mravko Maldonado
E
E
D003920:Diabetes Mellitus / Q000276:immunology*; D006801:Humans; D007371:Interferon-gamma / Q000502:physiology*; D007378:Interleukins / Q000502:physiology*; D007515:Islets of Langerhans / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000502:physiology*
D007378:Interleukins; D014409:Tumor Necrosis Factor-alpha; D007371:Interferon-gamma
Las células beta del páncreas y citocinas.