title: [The efficacy of substances with antihypoxic action in experimental hyperlipidemia].
abstract: Experiments on rats, guinea pigs and rabbits with hyperlipidemia induced by high-cholesterol diet have revealed that the specific antihypoxic drug oliphen has hypolipidemic effect which is least pronounced in oral GABA. Oliphen causes a significant increase in alpha-cholesterol (antiatherogenic lipoprotein cholesterol) decreased by hyperlipidemia. It is suggested that oliphen improves hepatic receptor-dependent uptake and atherogenic lipoprotein degradation.
authors.forename: V E
authors.initials: VE
authors.lastname: Ryzhenkov
authors.forename: O V
authors.initials: OV
authors.lastname: Remezova
authors.forename: V F
authors.initials: VF
authors.lastname: Triufanov
authors.forename: L E
authors.initials: LE
authors.lastname: Vasil'eva
mesh_terms: D000818:Animals; D002791:Cholesterol, Dietary / Q000008:administration & dosage; D002994:Clofibrate / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D006168:Guinea Pigs; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008055:Lipids / Q000097:blood; D008297:Male; D011817:Rabbits; D051381:Rats; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use*
chemical_list: D002791:Cholesterol, Dietary; D000960:Hypolipidemic Agents; D008055:Lipids; D005680:gamma-Aminobutyric Acid; D002994:Clofibrate
vernacular_title: Effektivnost' veshchestv antigipoksicheskogo deĭstviia pri éksperimental'noĭ giperlipidemii.