title: [Tissue plasminogen activator, its inhibitor and other parameters of fibrinolysis in blood of patients operated for mild hypertrophy of the prostate].
abstract: An increased blood fibrinolytic activity manifested by increased tissue plasminogen activator (t-PA) and decreased tissue plasminogen activator inhibitor (PAI-1) and increased FDP levels are seen in 40 patients with mild hypertrophy of prostate. Surgical treatment increased blood fibrinolytic activity manifested in the increase in t-PA, decrease in PAI-1, shortening of ELT, increase in FDP, and decrease in plasminogen and 2-AP activities. Blood fibrinolytic activity was the highest immediately after surgery with tendency to the gradual normalization. Positive ethanol test and decrease in thrombocyte count indicate and activation of blood clotting system induced by the tissue thrombo-elastins released during surgery. Subclinical DCI with the secondary increased fibrinolysis activation is present in patients with mild hypertrophy of the prostate both prior to and after surgery.
authors.affiliation: Katedry i Kliniki Urologii AM, Bydgoszczy.
authors.forename: I
authors.initials: I
authors.lastname: Iwan-Zietek
authors.forename: Z
authors.initials: Z
authors.lastname: Zietek
authors.forename: M
authors.initials: M
authors.lastname: Kotschy
authors.forename: D
authors.initials: D
authors.lastname: Rość
authors.forename: F
authors.initials: F
authors.lastname: Tyloch
authors.forename: M
authors.initials: M
authors.lastname: Cwiklińska-Jurkowska
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005342:Fibrinolysis / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015849:Plasminogen Inactivators / Q000097:blood*; D010976:Platelet Count; D011470:Prostatic Hyperplasia / Q000097:blood* / Q000601:surgery*; D010959:Tissue Plasminogen Activator / Q000097:blood*
chemical_list: D015849:Plasminogen Inactivators; D010959:Tissue Plasminogen Activator
vernacular_title: Tkankowy aktywator plazminogenu i jego inhibitor oraz inne parametry układu fibrynolizy we krwi chorych operowanych z powodu łagodnego przerostu gruczołu krokowego.