title: Preliminary studies on the effect of Ukrain (Tris(2-([5bS-(5ba,6b,12ba)]- 5b,6,7,12b,13,14-hexahydro-13-methyl[1,3] benzodioxolo[5,6-v]-1-3- dioxolo[4,5-i]phenanthridinium-6-ol]-Ethaneaminyl)Phosphinesulfide.6HCl ) on the immunological response in patients with malignant tumours.
abstract: Preliminary clinical observations and studies on immunological response-indicators were made in eight patients with malignant tumours, who had been administered parenteral injections of Ukrain. The results suggest that the preparation is a non-toxic immunostimulator inducing production of thymodependent T lymphocytes. The preparation improves general health of patients, has anti-allergic action, and sedative and anti-inflammatory effects. It can inhibit growth of malignant tumours.
authors.affiliation: Hospital for Obstetrics and Gynaecology, Lublin, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Danilos
authors.forename: W
authors.initials: W
authors.lastname: Zbroja-Sontag
authors.forename: E
authors.initials: E
authors.lastname: Baran
authors.forename: L
authors.initials: L
authors.lastname: Kurylcio
authors.forename: L
authors.initials: L
authors.lastname: Kondratowicz
authors.forename: L
authors.initials: L
authors.lastname: Jusiak
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000276:immunology; D000328:Adult; D000470:Alkaloids / Q000009:adverse effects / Q000627:therapeutic use*; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects / Q000627:therapeutic use*; D001600:Berberine Alkaloids; D001943:Breast Neoplasms / Q000188:drug therapy / Q000276:immunology; D001984:Bronchial Neoplasms / Q000188:drug therapy / Q000276:immunology; D002277:Carcinoma / Q000188:drug therapy / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000188:drug therapy / Q000276:immunology; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy / Q000276:immunology*; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000276:immunology; D010617:Phenanthridines; D012397:Rosette Formation; D012878:Skin Neoplasms / Q000188:drug therapy / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D014594:Uterine Neoplasms / Q000188:drug therapy / Q000276:immunology
chemical_list: D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D001600:Berberine Alkaloids; D010617:Phenanthridines; C060921:ukrain