title: [Influence of high dose intravenous immunoglobulins (IVIG) on HSV-1 infection in immunosuppressed mice].
abstract: Influence of low and high doses of intravenous immunoglobulin (IVIG) was compared on the basis of survival studies of mice infected with temperature sensitive (ts 28 degrees C) clone of Herpes simplex virus (HSV-1) after previous treatment with cyclophosphamide (CY), Sandoglobulin containing intact IgG and Gamma-Venin containing only fragments of (Fab)2 IgG were used. It was found that 4 and 16 mg doses protected animals in contrast to the 32 mg dose of Sandoglobulin which protected mice in only small degree.
authors.affiliation: Zakład Wirusologii PZH w Warszawie.
authors.forename: B
authors.initials: B
authors.lastname: Litwińska
authors.forename: B
authors.initials: B
authors.lastname: Bucholc
authors.forename: M
authors.initials: M
authors.lastname: Kańtoch
mesh_terms: D000818:Animals; D005260:Female; D006561:Herpes Simplex / Q000628:therapy*; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D007165:Immunosuppression Therapy; D008297:Male; D051379:Mice
chemical_list: D016756:Immunoglobulins, Intravenous
vernacular_title: Wpływ wysokich dawek gammaglobuliny (IVIG) na przebieg zakazenia HSV-1 u myszy poddanych immunosupresji.