[The hematopoietic characteristics of laryngeal cancer patients undergoing thermoradiosensitization].
Peripheral blood and bone marrow were studied in 46 patients suffering laryngeal cancer. Two schedules of radiotherapy with and without local hyperthermia were used. Complex hematologic study included electron microscopy of the bone marrow. Apart from general hematologic parameters, partial erythro- and granulocytograms of the bone marrow, mitotic index of karyocytes and morphologic anomalies of erythrokaryocytes were studied. Hematologic studies were conducted both before and after a course of radiotherapy. Adverse effect of hyperthermia and radiation therapy on cells of the granulocytic and immunologic component of hemopoiesis was established.
Khait
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SE
Andreev
V G
VG
Kurilets
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ES
D000328:Adult; D001773:Blood Cells / Q000528:radiation effects / Q000648:ultrastructure; D001853:Bone Marrow / Q000528:radiation effects / Q000648:ultrastructure; D002452:Cell Count / Q000528:radiation effects; D003131:Combined Modality Therapy; D005720:Gamma Rays / Q000627:therapeutic use; D006410:Hematopoiesis / Q000528:radiation effects*; D006801:Humans; D006979:Hyperthermia, Induced; D007822:Laryngeal Neoplasms / Q000097:blood* / Q000532:radiotherapy*; D008875:Middle Aged; D011879:Radiotherapy Dosage
Osobennosti krovetvoreniia u bol'nykh rakom gortani v usloviiakh termoradiosensibilizatsii.