Organic delusional syndrome associated with tamoxifen treatment.
The authors describe two cases of tamoxifen-induced organic delusional syndrome that resulted from administration of 40 mg daily for the adjuvant treatment of breast carcinoma. After discontinuation of the tamoxifen therapy, the psychiatric episode resolved within 2 to 4 weeks. Because tamoxifen might cause delusional syndrome, the authors recommend full psychiatric evaluation in appropriate cases.
Ron
I G
IG
Oncology Department, Ichilov Hospital, Tel-Aviv, Israel.
Inbar
M J
MJ
Barak
Y
Y
Stier
S
S
Chaitchik
S
S
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000601:surgery; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000188:drug therapy* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003702:Delusions / Q000139:chemically induced*; D005260:Female; D006801:Humans; D015411:Mastectomy, Modified Radical; D010259:Paranoid Disorders / Q000139:chemically induced; D019966:Substance-Related Disorders / Q000209:etiology*; D013629:Tamoxifen / Q000009:adverse effects*
D013629:Tamoxifen