title: Absence of HLA-B8 and HLA-DR3 in Japanese patients with Sjögren's syndrome positive for anti-SSA(Ro).
abstract: Forty Japanese anti-SSA(Ro) positive patients with Sjögren's syndrome were typed for HLA-A, B, C, DR and DQ antigens. No patient had either HLA-B8 or HLA-DR3 which has been reportedly associated with the immune response to SSA(Ro) antigens in white and black patients. Our patients had higher frequencies of HLA-DRw8 and HLA-DRw52 than the control population.
authors.affiliation: Department of Dermatology, Nara Medical University, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Miyagawa
authors.forename: K
authors.initials: K
authors.lastname: Dohi
authors.forename: H
authors.initials: H
authors.lastname: Shima
authors.forename: T
authors.initials: T
authors.lastname: Shirai
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001324:Autoantigens / Q000032:analysis*; D005260:Female; D015795:HLA-B8 Antigen / Q000032:analysis*; D015803:HLA-DR3 Antigen / Q000032:analysis*; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D020733:RNA, Small Cytoplasmic; D012261:Ribonucleoproteins / Q000032:analysis*; D012859:Sjogren's Syndrome / Q000453:epidemiology / Q000276:immunology*; D000099207:SS-A Antigen
chemical_list: D001324:Autoantigens; D015795:HLA-B8 Antigen; D015803:HLA-DR3 Antigen; D020733:RNA, Small Cytoplasmic; D012261:Ribonucleoproteins; D000099207:SS-A Antigen; C116006:RO60 protein, human