title: [Biochemical indices of liver function in workers from repair brigades in chemical plants "Organika-Azot" in Jaworz].
abstract: In order to assess the functional state of the liver in 45 repair service workers of a chemical plant producing pesticides the serum concentration and electrophoretic pattern of proteins, the concentration of bilirubin and the activity of alkaline phosphatase, gamma-glutamyl- transpeptidase, alanine and aspartate aminotransferase, and lactic and malic dehydrogenase were determined. As compared to 35 healthy controls, not exposed to noxious chemicals, a significantly lower serum protein concentration with higher percentage of gamma-globulins and lower albumins and alpha 2-globulins were observed, the serum alanine and aspartate aminotransferase activities were significantly elevated. Ultrasound examination of the hepatic structure revealed liver steatosis in 11 (24.4%) workers. The results of our study point to a discrete lesion of the liver.
authors.affiliation: II Kliniki Chorób Wewnetrznych Slaskiej Akademii Medycznej, Katowicach.
authors.forename: S
authors.initials: S
authors.lastname: Kossmann
authors.forename: Z
authors.initials: Z
authors.lastname: Magner-Krezel
mesh_terms: D000328:Adult; D000409:Alanine / Q000097:blood; D000418:Albumins / Q000378:metabolism; D001219:Aspartate Aminotransferases / Q000097:blood; D001798:Blood Proteins / Q000378:metabolism; D002617:Chemical Industry; D056486:Chemical and Drug Induced Liver Injury; D006801:Humans; D008107:Liver Diseases / Q000000981:diagnostic imaging*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging*; D010575:Pesticides / Q000009:adverse effects*; D014463:Ultrasonography; D000511:alpha-Macroglobulins / Q000378:metabolism; D005719:gamma-Globulins / Q000378:metabolism
chemical_list: D000418:Albumins; D001798:Blood Proteins; D010575:Pesticides; D000511:alpha-Macroglobulins; D005719:gamma-Globulins; D001219:Aspartate Aminotransferases; D000409:Alanine
vernacular_title: Biochemiczne wskaźniki funkcji watroby u pracowników brygad remontowych Zakładów Chemicznych "Organika-Azot" w Jaworznie.