[An experimental study of ocular contusion and its hemodynamic changes].
The hemodynamic changes in rabbit eyes following contusion were studied with rheoophthalmography (ROG), in which the wave amplitudes were markedly reduced and then recovered in 3 weeks, while in the anisodine-I treated group they recovered in 2 weeks. Contusion of 3 joules disrupted the choroidal circulation and damaged the retina. Anisodine-I improved the vasomotor functions of the choroidal vessels and was effective in treatment of ocular contusion. ROG was a sensitive objective means of estimating the severity of ocular contusion and evaluating the therapeutic effects.
Dou
H L
HL
Department of Ophthalmology, PLA General Hospital, Beijing.
Song
C
C
D000818:Animals; D002829:Choroid / Q000098:blood supply*; D003288:Contusions / Q000188:drug therapy / Q000503:physiopathology*; D005131:Eye Injuries / Q000188:drug therapy / Q000503:physiopathology*; D006439:Hemodynamics / Q000187:drug effects; D010992:Plethysmography, Impedance; D011817:Rabbits; D012039:Regional Blood Flow / Q000187:drug effects; D012171:Retinal Vessels / Q000187:drug effects*; D012602:Scopolamine Derivatives / Q000627:therapeutic use*
D012602:Scopolamine Derivatives; C012183:anisodine