[An etiological study on fulminant viral hepatitis].
Viral markers were studied in 79 cases of viral hepatitis with hepatic failure. The results were shown as follows: 8 cases were positive for anti-HAV IgM (10.12%); 76 cases positive for HBsAg or anti-HBc IgM (96.20%) and 41 cases positive for anti-HCV antibodies (51.89%). Among those with anti-HCV positive, 35 cases were co-infected with HBV, 5 cases with HAV and/or HCV, only one was infected with HCV alone 2 cases were HD-Ag positive (2.52%) and one not identified (1.27%). With the reference of clinical findings, patients co-infected with HBV/HCV or anti-HBc IgM positive were more critical and usually entail higher mortality. In cases with HCV co-infections, the positive HBV replication markers seems to be reduced. Hepatic failure without HBV replicative markers had a high rate of hepatic coma as well as poor outcome.
Zhao
Y R
YR
Chong qing University of Medical Sciences.
Zhang
D F
DF
Pan
C Q
CQ
D000328:Adult; D000368:Aged; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016174:Hepacivirus / Q000276:immunology; D006501:Hepatic Encephalopathy / Q000209:etiology; D006508:Hepatitis Antibodies / Q000032:analysis*; D006510:Hepatitis B Antibodies / Q000032:analysis; D018937:Hepatitis C Antibodies; D003698:Hepatitis Delta Virus / Q000276:immunology; D006525:Hepatitis, Viral, Human / Q000150:complications / Q000276:immunology* / Q000382:microbiology; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D015163:Superinfection / Q000276:immunology*
D006508:Hepatitis Antibodies; D006510:Hepatitis B Antibodies; D018937:Hepatitis C Antibodies