[The determination of beta-casein gene expression and the assessment of hormonal homeostasis in gynecomastia patients and in breast cancer in men].
beta-Casein genes expression in breast epithelium was studied in male patients with various forms of gynecomastia and cancer. Blood serum levels of pituitary, sex and glucocorticoid hormones were assayed in 29 patients with gynecomastia and 22 cases of breast cancer, and in 25 of them beta-casein genes expression was evaluated additionally. Activation of the above genes was established in the tissues studied. Their level proved to be in a correlation with that of prolactin.
Ganina
K P
KP
Liubimova
Iu Iu
IuIu
Tarutinov
V I
VI
Topchiĭ
V B
VB
Fedorova
L V
LV
D000328:Adult; D001943:Breast Neoplasms / Q000097:blood / Q000235:genetics*; D002364:Caseins / Q000235:genetics*; D004247:DNA / Q000235:genetics; D004273:DNA, Neoplasm / Q000235:genetics; D004967:Estrogens / Q000097:blood; D005786:Gene Expression Regulation / Q000235:genetics*; D015972:Gene Expression Regulation, Neoplastic / Q000235:genetics*; D006065:Gonadotropins, Pituitary / Q000097:blood; D006177:Gynecomastia / Q000097:blood / Q000235:genetics*; D006706:Homeostasis / Q000235:genetics*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D013739:Testosterone / Q000097:blood
D002364:Caseins; D004273:DNA, Neoplasm; D004967:Estrogens; D006065:Gonadotropins, Pituitary; D013739:Testosterone; D004247:DNA; D006854:Hydrocortisone
Opredelenie ékspressii genov beta-kazeina i otsenka gormonal'nogo gomeostaza u bol'nykh s ginekomastieĭ i rakom molochnoĭ zhelezy u muzhchin.