title: The prevalence of hepatitis C virus antibodies in patients treated with continuous ambulatory peritoneal dialysis.
abstract: OBJECTIVE
  To assess the prevalence of anti-HCV (hepatitis C virus antibodies) in continuous ambulatory peritoneal dialysis (CAPD) patients and staff members.
  
  
  METHODS
  Fifty-nine serum samples were collected and tested by an enzyme immunoassay for anti-HCV. Records and past history of blood transfusion and hemodialysis were reviewed. Results were analyzed using the Fisher's exact test.
  
  
  METHODS
  A medical college-operated teaching hospital.
  
  
  METHODS
  Fifty-two patients and 7 staff members from the Chang Gung Memorial Hospital CAPD unit were studied.
  
  
  RESULTS
  Anti-HCV prevalence in patients and staff were 15.4% and 0%. A history of maintenance hemodialysis was associated with a higher prevalence of anti-HCV (33.3% versus 5.9% without hemodialysis, p = 0.015). The prevalence of anti-HCV did not increase with longer CAPD duration. Among those with an episode of hepatitis, higher prevalence of anti-HCV was observed (57.1% versus 8.9% without hepatitis, p = 0.0073).
  
  
  CONCLUSIONS
  HCV is an important agent of hepatitis in CAPD patients. The risk of HCV infection among CAPD staff members is negligible. CAPD offers better control of HCV infection among patients with end-stage renal failure.
authors.affiliation: Division of Nephrology, Chang Gung Memorial Hospital, Chang Gung Medical College, Taipei, Taiwan, R.O.C.
authors.forename: C C
authors.initials: CC
authors.lastname: Huang
authors.forename: M S
authors.initials: MS
authors.lastname: Wu
authors.forename: D Y
authors.initials: DY
authors.lastname: Lin
authors.forename: Y F
authors.initials: YF
authors.lastname: Liaw
mesh_terms: D001803:Blood Transfusion; D005260:Female; D006436:Hemodialysis Units, Hospital; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000032:analysis*; D006526:Hepatitis C / Q000453:epidemiology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory; D015995:Prevalence; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D013624:Taiwan / Q000453:epidemiology; D013997:Time Factors
chemical_list: D006508:Hepatitis Antibodies