Effect of short-term ethanol intake on antibody-dependent cell-mediated cytotoxicity (ADCC) in rats.
The present study was designed to evaluate the effect of short ethanol intake on ADCC activity in blood and spleen mononuclear cells. Wistar rats were fed a standard diet and drank 0.1 M ethanol solution for three days. Glucose and water controls were used in this experiment. Increased ADCC activity was found in ethanol consuming rats in the blood and spleen as compared to both controls. Our findings support the assumption that ADCC may play an important role in liver disease of alcoholics.
Sabol
M
M
Department of Animal Physiology, Faculty of Science, Safárik University, Kosice.
Paulíková
E
E
D000428:Alcohol Drinking / Q000276:immunology*; D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity / Q000187:drug effects*; D001769:Blood / Q000276:immunology; D001835:Body Weight / Q000187:drug effects; D003601:Cytotoxicity Tests, Immunologic; D005947:Glucose / Q000276:immunology; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000276:immunology
D005947:Glucose