title: Influence of irrigation and intracanal dressing on the healing process of dogs' teeth with apical periodontitis.
abstract: Dogs' teeth with apical periodontitis were treated endodontically, Dakin's solution being used in an experimental group as the irrigation solution, and camphorated paramonochlorophenol as an intracanal dressing. For a second group of teeth, the irrigation solution used was physiologic saline, dry cotton only being placed into the pulpal chamber to take the place of an intracanal dressing. In a second visit, overinstrumentation and a new application of the same kind of dressing were performed, the root canals being then filled with gutta-percha cones and zinc oxide-eugenol cement. Other specimens were treated, in one visit, where physiologic saline or Dakin's solution were the irrigation solutions. The animals were sacrificed 6 months after the obturation of the root canals. Histologic exams showed better results for the experimental group where Dakin's solution and camphorated paramonochlorophenol had been used, with signs of repair characterized by newly formed cementum and bone tissue, as well as a marked reduction in size of the periapical lesions. No differences were seen in the results with physiologic saline or Dakin's solution as irrigants.
authors.affiliation: Department of Endodontics, UNESP, Araçatuba, Sao Paulo, Brasil.
authors.forename: R
authors.initials: R
authors.lastname: Holland
authors.forename: I J
authors.initials: IJ
authors.lastname: Soares
authors.forename: I M
authors.initials: IM
authors.lastname: Soares
mesh_terms: D000818:Animals; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002164:Camphor / Q000494:pharmacology / Q000627:therapeutic use; D002733:Chlorophenols / Q000494:pharmacology / Q000627:therapeutic use; D004285:Dogs; D004338:Drug Combinations; D006097:Granulation Tissue; D010485:Periapical Periodontitis / Q000188:drug therapy* / Q000473:pathology; D012388:Root Canal Irrigants / Q000494:pharmacology / Q000627:therapeutic use*; D012973:Sodium Hypochlorite / Q000494:pharmacology / Q000627:therapeutic use; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000891:Anti-Infective Agents, Local; D002733:Chlorophenols; D004338:Drug Combinations; D012388:Root Canal Irrigants; D002164:Camphor; C029804:camphorated parachlorophenol; D012973:Sodium Hypochlorite