title: Low frequency of isozyme 2 acid a-glucosidase in Greece.
abstract: The isozyme type 2 of acid a-glucosidase, identified by "affinity" starch gel electrophoresis, was found to have a gene frequency of 0.001 in an unselected Greek population from Southwestern Greece. The estimated frequency of the heterozygote in the population is 1 in 500 and of type 2 homozygote 10(-6). This frequency is by far lower than that reported in Europeans and other populations. This may be a characteristic of the Greek gene pool at the acid a-glucosidase locus or it may be present in populations of neighbouring countries as well.
authors.affiliation: Department of Pediatrics, University of Patras, School of Medicine, Greece.
authors.forename: N G
authors.initials: NG
authors.lastname: Beratis
authors.forename: G
authors.initials: G
authors.lastname: Decavalas
authors.forename: P
authors.initials: P
authors.lastname: Ladas
mesh_terms: D000483:Alleles; D005260:Female; D005787:Gene Frequency; D006115:Greece; D006579:Heterozygote; D006801:Humans; D007527:Isoenzymes / Q000235:genetics*; D010641:Phenotype; D010920:Placenta / Q000201:enzymology; D011247:Pregnancy; D000520:alpha-Glucosidases / Q000235:genetics*
chemical_list: D007527:Isoenzymes; D000520:alpha-Glucosidases