title: True 47,XXX in a patient with premature ovarian failure: the first reported case in Thailand.
abstract: A case of triple-X female with premature ovarian failure was reported. The patient was a 23-year-old, single, Thai woman who presented with primary amenorrhea, incomplete development of the secondary sex characteristics, elevated levels of serum gonadotropins, and decreased estrogen concentration. Immunological abnormalities were not identified by antinuclear antibody, rheumatoid factor, antimicrosomal antibody and antithyroglobulin antibody studies. Cyclic estrogen-progestin was given and withdrawal bleeding occurred. The present case represents the utilization of chromosomal analysis in a patient with delayed sexual development, or primary amenorrhea and elevated serum gonadotropin levels.
authors.affiliation: Department of Obstetrics & Gynaecology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Tungphaisal
authors.forename: U
authors.initials: U
authors.lastname: Jinorose
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000150:complications; D005260:Female; D006801:Humans; D007621:Karyotyping; D016649:Primary Ovarian Insufficiency / Q000235:genetics*; D012729:Sex Chromosome Aberrations; D012741:Sexual Maturation; D013785:Thailand; D014960:X Chromosome