[Slow ventricular tachycardia caused by naftidrofuryl overdose (naftidrofuryl and ventricular tachycardia)].
Treatment with intravenous naftidrofuryl may be complicated by ventricular arrhythmias. A case of slow ventricular tachycardia occurring in a 65-year-old man with a dilated cardiomyopathy following an accidental overdose of naftidrofuryl (2 x 200 mg ampules in 250 ml of 5% glucose solution in 2 hours) prescribed for complicated arterial disease of the lower limbs is reported. This sustained ventricular tachycardia converted spontaneously after several hours. This case emphasises the risk of arrhythmogenic effects of this drug and indicates the need for careful monitoring when it is used intravenously in patients with underlying heart disease.
Malaterre
H R
HR
Service de cardiologie, CHU Nord, Marseille.
Ferracci
A
A
Ebagosti
A
A
Faugier
J P
JP
Charles
D
D
Levy
S
S
D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000188:drug therapy; D062787:Drug Overdose; D006801:Humans; D007049:Iatrogenic Disease; D008297:Male; D009257:Nafronyl / Q000008:administration & dosage / Q000009:adverse effects*; D017180:Tachycardia, Ventricular / Q000139:chemically induced*
D009257:Nafronyl
Tachycardie ventriculaire lente par surdosage en naftidrofuryl (naftidrofuryl et TV).