[The agglutinability of cholera O-monoclonal immunoglobulins].
A set of 10 monoclonal antibodies specific for vibrio species and of 5 monoclonal antibodies specific for serovar (Ogawa) was studied. These monoclonal antibodies were directed toward V. cholerae O1 antigen in agglutination reaction and on slide plates. Monoclonal antibodies agglutinating typical strains of cholera vibrios with titration range from 1: 6000 to 1: 25,000 were selected. MA were revealed to interact with cholera vibrio strains with reduced agglutinability. The set of agglutinating O monoclonal immunoglobulins was developed for laboratory identification of cholera O1 vibrios.
Alekseeva
L P
LP
Burlakova
O S
OS
Balakhnova
V V
VV
D000372:Agglutination Tests; D000373:Agglutinins / Q000097:blood*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000097:blood* / Q000302:isolation & purification; D000918:Antibody Specificity; D000939:Epitopes / Q000276:immunology; D006825:Hybridomas / Q000276:immunology; D007136:Immunoglobulins / Q000097:blood* / Q000302:isolation & purification; D051379:Mice; D008807:Mice, Inbred BALB C; D019081:O Antigens; D011135:Polysaccharides, Bacterial / Q000276:immunology; D012703:Serotyping; D013045:Species Specificity; D014734:Vibrio cholerae / Q000145:classification / Q000276:immunology*
D000373:Agglutinins; D000911:Antibodies, Monoclonal; D000939:Epitopes; D007136:Immunoglobulins; D019081:O Antigens; D011135:Polysaccharides, Bacterial
K voprosu ob aggliutinabel'nosti kholernykh O-monoklonal'nykh immunoglobulinov.