title: A pilot study of dried blood spot testing for HIV antibody in neonates.
abstract: An unlinked anonymous HIV antibody study of neonates, using surplus dried blood spots on Guthrie cards, was introduced as a means of estimating the prevalence of HIV infection in childbearing women. From March 1990 to February 1992, blood spots from 14,520 infants were tested for anti-HIV, using an HIV IgG antibody capture particle-adherence test; only one sample gave a confirmed positive reaction. This type of study involves no interference in routine care and can be operated without difficulty in a district general hospital setting where neonatal metabolic screening is performed.
authors.affiliation: Reading Public Health Laboratory, Royal Berkshire Hospital.
authors.forename: J V
authors.initials: JV
authors.lastname: Dadswell
authors.forename: B
authors.initials: B
authors.lastname: Dowding
authors.forename: M
authors.initials: M
authors.lastname: Fletcher
authors.forename: G J
authors.initials: GJ
authors.lastname: Pinney
authors.forename: J
authors.initials: J
authors.lastname: Sellwood
authors.forename: D L
authors.initials: DL
authors.lastname: Williams
mesh_terms: D015492:AIDS Serodiagnosis / Q000379:methods*; D004739:England / Q000453:epidemiology; D005260:Female; D015483:HIV Antibodies / Q000097:blood*; D015528:HIV Seroprevalence; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000379:methods*; D010865:Pilot Projects; D016387:Women's Health
chemical_list: D015483:HIV Antibodies; D007074:Immunoglobulin G