title: [Various clonidine drops in treatment of glaucoma].
abstract: Seventeen patients with glaucoma were given bilaterally a single drop of Isoglaucon (Clonidine hydrochloride) of various volume (15 microliters and 40 microliters) and various concentrations of the drug (0.125%, 0.25%, 0.50%) according to the principle of a double blind trial. In comparison with placebo all sorts of Isoglaucon drops cause a statistically important reduction of intraocular pressure; an essential lowering of the general systolic and diastolic pressure (a side effect of the treatment) appeared after application of a larger drop (40 microliters) of a 0.5% concentration. By reducing the content of the drug in the drop or reducing its volume one can avoid the fall in the general blood pressure.
authors.affiliation: Kliniki Okulistycznej Slaskiej Akademii Medycznej, Katowicach.
authors.forename: A
authors.initials: A
authors.lastname: Szymański
authors.forename: B
authors.initials: B
authors.lastname: Brozyna-Zyłka
authors.forename: A
authors.initials: A
authors.lastname: Sobieraj
authors.forename: D
authors.initials: D
authors.lastname: Otrzonsek
mesh_terms: D000368:Aged; D003000:Clonidine / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged
chemical_list: D003000:Clonidine
vernacular_title: Rodzaje kropli isoglauconu w leczeniu jaskry.