title: [Ex situ-in vivo hepatic resection. Technique and initial results].
abstract: Extracorporeal liver surgery has been proposed with the aim to increase the resectability rate in patients with advanced tumors. In order to avoid the inherent section of the hepatic pedicle we propose ex situ-in vivo liver surgery. The surgical procedure comprises complete mobilization and exteriorization of the liver which is rocked on the axis of the porta hepatis following section of the hepatic veins. Protection of the liver parenchyma against prolonged ischemia is obtained through cold portal perfusion (UW solution) and the use of an heat exchanger on which liver resections and vascular procedures are performed. The procedure also encompasses the use of veno-venous bypass during liver vascular exclusion. This procedure was performed in 2 patients with tumoral invasion of the 3 main hepatic veins and in 1 patient whose hemangioma was surrounding the hepatocaval confluence. Duration of hypothermic ischemia was 205, 225 and 230 minutes respectively. Postoperative course was uneventful in the 3 cases with an hospital stay of 25, 28 and 18 days. Ex situ-in vivo liver surgery allows completion of a surgical treatment in patients whose tumor appears unresectable with the use of conventional technics. This procedure may constitute an alternative to liver transplantation in highly selected cases.
authors.affiliation: Département de Chirurgie digestive et hépato-biliaire, hôpital Saint-Antoine, Paris.
authors.forename: T
authors.initials: T
authors.lastname: Hannoun
authors.forename: D
authors.initials: D
authors.lastname: Borie
authors.forename: P
authors.initials: P
authors.lastname: Balladur
authors.forename: E
authors.initials: E
authors.lastname: Delva
authors.forename: J P
authors.initials: JP
authors.lastname: Masini
authors.forename: E
authors.initials: E
authors.lastname: Levy
authors.forename: R
authors.initials: R
authors.lastname: Parc
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D007430:Intraoperative Care; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D011167:Portacaval Shunt, Surgical; D012034:Refrigeration / Q000379:methods
vernacular_title: Résections hépatiques ex situ-in vivo. Technique et résultats préliminaires.