Localization of proteins immunologically related to erythrocyte protein 4.1, spectrin and ankyrin in thyroid gland.
Analogues of erythrocyte protein 4.1, spectrin and ankyrin were examined in the thyroid gland of pig and rat by immunohistochemical techniques. Analysis with immunofluorescence microscopy revealed that the peripheral cytoplasm and apical-lateral plasma membrane of follicle epithelial cells of thyroid glands were stained with antibodies against erythrocyte protein 4.1, spectrin, or ankyrin. The results indicate that membrane skeletal protein lattice might exist in thyroid follicle epithelial cells.
Shimizu
T
T
Department of Dermatology, Hokkaido University School of Medicine, Sapporo, Japan.
Takakuwa
Y
Y
Koizumi
H
H
Ishibashi
T
T
Ohkawara
A
A
D000818:Animals; D017487:Ankyrins / Q000032:analysis*; D003598:Cytoskeletal Proteins; D008565:Membrane Proteins / Q000032:analysis*; D009479:Neuropeptides; D051381:Rats; D013049:Spectrin / Q000032:analysis*; D013552:Swine; D013961:Thyroid Gland / Q000378:metabolism*
D017487:Ankyrins; D003598:Cytoskeletal Proteins; D008565:Membrane Proteins; D009479:Neuropeptides; C028841:erythrocyte membrane band 4.1 protein; C120557:erythrocyte membrane protein band 4.1-like 1; D013049:Spectrin