[Thymus endocrine function and the immune system indices of cancer patients after neutron and gamma therapy].
Patients with head and neck and locomotor system tumors received neutron therapy in the total doses of 4-8 and 12-14 Gy which was followed by a pronounced dose-dependent decrease in the serum thymus factor and total blood-lymphocyte levels. The latter changes were predominantly due to a decrease in the non-T-non-B cell concentration. Following the treatment, a rise in the level of circulating immune complexes and those of IgA and IgG was observed. Changes in the immune system proved less apparent in patients with locomotor system cancer who had been given 20 Gy of gamma-ray radiation.
Grinevich
Iu A
IuA
Martynenko
S V
SV
Baraboĭ
V A
VA
Monich
A Iu
AIu
Tolstopiatov
B A
BA
Konovalenko
V F
VF
Protsyk
V S
VS
D000328:Adult; D000936:Antigen-Antibody Complex / Q000097:blood / Q000528:radiation effects; D005720:Gamma Rays / Q000627:therapeutic use; D006258:Head and Neck Neoplasms / Q000276:immunology / Q000378:metabolism / Q000532:radiotherapy*; D006801:Humans; D007107:Immune System / Q000276:immunology* / Q000528:radiation effects*; D007111:Immunity, Cellular / Q000528:radiation effects; D007136:Immunoglobulins / Q000097:blood / Q000528:radiation effects; D008875:Middle Aged; D009140:Musculoskeletal Diseases / Q000276:immunology / Q000503:physiopathology / Q000532:radiotherapy*; D009369:Neoplasms / Q000276:immunology / Q000378:metabolism / Q000532:radiotherapy; D009502:Neutrons; D011879:Radiotherapy Dosage; D013950:Thymus Gland / Q000378:metabolism* / Q000528:radiation effects*
D000936:Antigen-Antibody Complex; D007136:Immunoglobulins
Endokrinnaia funktsiia timusa i nekotorye pokazateli sostoiannia immunnoĭ systemy onkologicheskikh bol'nykh posle neĭtronnoĭ i gamma-terapii.