[A clinical investigation of rHuIFN alpha-1 in the treatment of herpes simplex virus keratitis].
A double blind clinical investigation on the treatment of 100 cases of HSV keratitis with rHuIFN alpha-1 and acyclovir instillations was carried out in 8 institutions in Beijing and elsewhere. Both eyedrops proved about equally effective with cure rates of 88.1% and 82.9% respectively. Until recently, 128 cumulative cases of various types of HSV keratitis treated with rHuIFN alpha-1 demonstrated a cure rate of 82.0%, indicating that topical rHuIFN alpha-1 was an effective nonspecific remedy for HSV keratitis.
Jin
X Y
XY
Beijing Institute of Ophthalmology.
D000212:Acyclovir / Q000627:therapeutic use; D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D016849:Keratitis, Herpetic / Q000628:therapy*; D008297:Male; D009883:Ophthalmic Solutions; D011994:Recombinant Proteins; D016037:Single-Blind Method
D007370:Interferon Type I; D009883:Ophthalmic Solutions; D011994:Recombinant Proteins; D000212:Acyclovir