title: The cytotoxic effects of denture base resin sealants.
abstract: Previous studies have shown that light-polymerized denture base resins have a cytotoxic effect on oral epithelial cells. The purpose of this in vitro study was to examine the effects of two denture base resin sealants when used on three light-polymerized denture base resins. Sample disks were examined for their effect on protein synthesis. Results indicate that one sealant protected the cells against toxic effects of the materials (P < .05), while one sealant enhanced toxicity up to 88% above that attributed to the resin alone.
authors.affiliation: Department of Prosthodontics, Medical College of Georgia, School of Denistry, Augusta 30912.
authors.forename: C A
authors.initials: CA
authors.lastname: Lefebvre
authors.forename: G S
authors.initials: GS
authors.lastname: Schuster
authors.forename: D W
authors.initials: DW
authors.lastname: Richardson
authors.forename: D J
authors.initials: DJ
authors.lastname: Barron
mesh_terms: D000180:Acrylic Resins / Q000494:pharmacology* / Q000633:toxicity*; D000704:Analysis of Variance; D000818:Animals; D002478:Cells, Cultured; D006224:Cricetinae; D017220:Dentin-Bonding Agents / Q000633:toxicity*; D003819:Denture Bases / Q000009:adverse effects*; D008422:Materials Testing; D014176:Protein Biosynthesis
chemical_list: D000180:Acrylic Resins; C078088:Astron LC; D017220:Dentin-Bonding Agents; C072648:Palaseal; C060386:Triad resin; C040291:Lucitone