[The depressive patient before depression].
This paper describes five prototypes of depression which develop from different temperamental substrates: timid-inhibited, dysthymic, hyperthymic, cyclothymic and irritable. They correspond, respectively, to anxious depressions, double depressions, anergic depressions, rapid-cycling depressions, and hostile depressions. The author argues that, despite a certain degree of overlap in pharmacologic response, each prototype has a relatively unique profile, including benzodiazepines, MAOIs, SSRIs, TCAs, lithium, low dose neuroleptics and anti-epileptic agents.
Akiskal
H S
HS
Section de Maladies Affectives, Université de Tennessee, Memphis 38105.
D001008:Anxiety Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D003527:Cyclothymic Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D003866:Depressive Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D007266:Inhibition, Psychological; D007508:Irritable Mood / Q000187:drug effects
Le déprimé avant la dépression.