[Immunomodulating properties of sera in normal pregnant women].
The purpose of this study was to analyze the immunosuppressive properties of sera of normal pregnant women. Effects of pregnancy sera on the proliferation of mitogen (PHA, Con A, PWM)-induced lymphocytes were examined in healthy primiparas. The sera of normal pregnant women inhibited the proliferation of PHA- and Con A- induced both autologous and allogenic lymphocytes (obtained from nonpregnant and pre-eclamptic women), while remaining neutral towards the proliferation of PWM- induced lymphocytes in comparison with fetal calf serum. The basic immunomodulatory activity of the sera in pregnant women was contained in the heat-stable fraction.
Malinowski
A
A
Katedry Połoznictwa i Ginekologii WAM, Lodzi.
Szpakowski
M
M
Tchórzewski
H
H
Zeman
K
K
Kowalczyk
T
T
Podciechowski
L
L
Oszukowski
P
P
D000328:Adult; D002455:Cell Division / Q000187:drug effects; D003208:Concanavalin A / Q000494:pharmacology; D005260:Female; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D008213:Lymphocyte Activation / Q000276:immunology; D008214:Lymphocytes / Q000187:drug effects; D008934:Mitogens / Q000494:pharmacology; D011247:Pregnancy / Q000097:blood / Q000276:immunology*; D012016:Reference Values
D008934:Mitogens; D003208:Concanavalin A
Immunomodulacyjne właściwości surowic zdrowych kobiet ciezarnych.