Long-term oral ciprofloxacin in the treatment of prosthetic valve endocarditis due to Pseudomonas aeruginosa.
Prosthetic valve endocarditis caused by Pseudomonas aeruginosa is refractory to medical treatment alone and early valve replacement is necessary. We describe a 40-year-old patient in whom endocarditis developed in the early postoperative period, and reoperation was not considered feasible. Ciprofloxacin was administered orally in order to suppress bacteremia for 36 months. Long-term oral ciprofloxacin may provide an opportunity in the treatment of prosthetic valve endocarditis caused by Ps. aeruginosa in patients who are unfavorable candidates for reoperation.
Uzun
O
O
Department of Medicine, Hacettepe University School of Medicine, Ankara, Turkey.
Akalin
H E
HE
Unal
S
S
Demircin
M
M
Yorgancioglu
A C
AC
Ugurlu
B
B
D000284:Administration, Oral; D000328:Adult; D001021:Aortic Valve; D002939:Ciprofloxacin / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004697:Endocarditis, Bacterial / Q000188:drug therapy*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008943:Mitral Valve; D016459:Prosthesis-Related Infections / Q000188:drug therapy*; D011552:Pseudomonas Infections / Q000188:drug therapy*
D002939:Ciprofloxacin