On the physiological significance of tumor necrosis factor-alpha in the human amniotic fluid.
Tumor Necrosis Factor (TNF)-alpha and Interleukin (IL)-1 beta levels have been measured in 16 weeks gestation amniotic fluids and mother's sera. Detectable levels of TNF-alpha were found in amniotic fluids, while IL-1 beta was absent. No cytokines were detected in mother's sera. The possible role of TNF-alpha as growth factor for fetal hematopoietic cells is discussed.
Covelli
V
V
Clinica Neurologica II Medical School, University of Napoli, Italy.
Jaccarino
M
M
Massari
F
F
Jaccarino
S
S
Munno
I
I
Marinaro
M
M
Gesario
A
A
Pellegrino
N M
NM
Jirillo
E
E
D000209:Acute-Phase Proteins / Q000032:analysis; D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry* / Q000502:physiology; D005260:Female; D006801:Humans; D007375:Interleukin-1 / Q000032:analysis / Q000097:blood; D011247:Pregnancy; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis / Q000502:physiology*
D000209:Acute-Phase Proteins; D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha