title: [Transient hyperphosphatasemia of infancy].
abstract: Transient hyperphosphatasemia of infancy was diagnosed in 4 children hospitalized during a 6-month period (0.3% of all hospitalized children). The characteristic features of this disorder are: 1. elevation of serum alkaline phosphatase (of both liver and bone origin) up to 3-30 times the upper limit of normal for age (usually discovered during intercurrent infection); 2. return of the serum alkaline phosphatase to normal in a few weeks; 3. no residual clinical or laboratory evidence of bone or liver disease. The child is usually less than 5 years old. Recognition of the benign nature of this disorder prevents extensive laboratory workup and unnecessary anxiety.
authors.affiliation: Pediatrics Dept., Beilinson Medical Center, Petah Tikva.
authors.forename: B
authors.initials: B
authors.lastname: Garty
authors.forename: D
authors.initials: D
authors.lastname: Stayer
authors.forename: D
authors.initials: D
authors.lastname: Harell
authors.forename: B
authors.initials: B
authors.lastname: Cornblut
authors.forename: M
authors.initials: M
authors.lastname: Nitzan
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood*; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D013997:Time Factors
chemical_list: D000469:Alkaline Phosphatase