[Effect of storage duration and irradiation dose on in vitro aggregation of thrombocytes].
We studied the influence of storage (1-5 days) and gamma irradiation (0, 25, 50, 100 Gy) on the in vitro aggregability of stored platelets. Platelet aggregation was measured using the method of Born and Breddin and the aggregating agents ADP, collagen, ristocetin and arachidonic acid. With increasing time of storage the ADP-, collagen- and ristocetin-induced platelet aggregation was significantly diminished. On the other hand, the irradiation even with 100 Gy had no additional effect.
Möckl
C
C
Abteilung für Hämatologie und Transfusionsmedizin, Zentralklinikums Augsburg, BRD.
Behr
W
W
Schlimok
G
G
D016913:Blood Component Transfusion; D001793:Blood Preservation; D004307:Dose-Response Relationship, Radiation; D006087:Graft vs Host Reaction / Q000528:radiation effects; D006801:Humans; D010974:Platelet Aggregation / Q000528:radiation effects*; D010983:Plateletpheresis; D013997:Time Factors
Einfluss von Lagerungsdauer und Bestrahlungsdosis auf das In-vitro-Aggregationsverhalten von Thrombozyten.