title: Agranulocytosis during treatment with fluconazole.
abstract: Fluconazole, a new effective triazole antifungal agent, has been reported to cause fewer adverse reactions than amphotericin B. A patient who was diagnosed as having agranulocytosis and thrombocytopenia after treatment with fluconazole was investigated and recovered after withdrawal of the antifungal therapy. This case suggests the need for careful haematological observation during the treatment with fluconazole.
authors.affiliation: Third Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Murakami
authors.forename: H
authors.initials: H
authors.lastname: Katahira
authors.forename: T
authors.initials: T
authors.lastname: Matsushima
authors.forename: T
authors.initials: T
authors.lastname: Sakura
authors.forename: J
authors.initials: J
authors.lastname: Tamura
authors.forename: M
authors.initials: M
authors.lastname: Sawamura
authors.forename: J
authors.initials: J
authors.lastname: Tsuchiya
mesh_terms: D000328:Adult; D000380:Agranulocytosis / Q000139:chemically induced*; D005260:Female; D015725:Fluconazole / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D013921:Thrombocytopenia / Q000139:chemically induced
chemical_list: D015725:Fluconazole