title: Carbamazepine-induced systemic lupus erythematosus-like disease.
abstract: A 14-year-old female developed systemic lupus erythematosus (SLE)-like symptoms, rash, fever, leukopenia and positive anti-nuclear antibody (ANA) two weeks after administration of carbamazepine (CBZ; Tegretol) used against benign Rolandic epilepsy. Clinical symptoms and leukopenia normalized after discontinuation of CBZ and administration of prednisolone at 40 mg. The cases of CBZ-induced SLE reported in the literature were reviewed.
authors.affiliation: Department of Internal Medicine II, Fukushima Medical College, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kanno
authors.forename: M
authors.initials: M
authors.lastname: Miyata
authors.forename: Y
authors.initials: Y
authors.lastname: Kazuta
authors.forename: Y
authors.initials: Y
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Nishimaki
authors.forename: R
authors.initials: R
authors.lastname: Kasukawa
mesh_terms: D000293:Adolescent; D002220:Carbamazepine / Q000009:adverse effects*; D004827:Epilepsy / Q000188:drug therapy; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D002220:Carbamazepine; D011239:Prednisolone