title: Effects of electroacupuncture of "zusanli" acupoint on high blood pressure and blood hyperviscosity in stress rats.
abstract: Elevation of blood pressure (BP) and blood viscosity (BV) was induced in unanesthetized Wistar rats by fixing and hanging. Electroacupuncture of "Zusanli" acupoint or microinjection of GABA (60 micrograms/10 microliters) into the IV ventricle of the brain could lower the high BP and BV induced by fixed-hanging, which could be blocked by a microinjection of GABAA receptor antagonist bicuculline (60 micrograms/10 microliters). The results showed that the depressant effect of electroacupuncture of "Zusanli" acupoint on high BP and blood hyperviscosity induced by fixed-hanging might be mediated by the activation of GABAA receptors in the brain.
authors.affiliation: Department of Physiology, Shanghai Medical University.
authors.forename: Y X
authors.initials: YX
authors.lastname: Jin
authors.forename: Q
authors.initials: Q
authors.lastname: Fu
authors.forename: X Q
authors.initials: XQ
authors.lastname: Guo
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy; D000818:Animals; D001809:Blood Viscosity; D015671:Electroacupuncture; D006973:Hypertension / Q000097:blood / Q000209:etiology / Q000628:therapy*; D007276:Injections, Intraventricular; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013315:Stress, Psychological; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology
chemical_list: D005680:gamma-Aminobutyric Acid