title: Issues of concern in the standardization and harmonization of drug trials in Europe: health-related quality of life, ESCT meeting, Strasbourg, 23-24 May 1991.
abstract: Overviews of the development of the concept of quality of life from a medical viewpoint, and the need for new models and methods to assess health-related quality of life were presented, along with WHO, FDA and European regulatory viewpoints and a discussion on the measurement and valuation of health by social judgement, at the health-related quality of life session at an ESCT meeting on issues of concern in the standardization and harmonization of drug trials in Europe. It was concluded that, for the present, all three types of measurements of quality of life--individual, disease-specific, and generic scales--should be used in research to look for convergent versus divergent validity.
authors.affiliation: Frederiksborg General Hospital, Hillerød, Denmark.
authors.forename: P
authors.initials: P
authors.lastname: Bech
mesh_terms: D002986:Clinical Trials as Topic / Q000592:standards*; D005060:Europe; D017408:Guidelines as Topic; D006801:Humans; D017146:Models, Organizational; D011788:Quality of Life; D012106:Research / Q000458:organization & administration / Q000592:standards