title: [Tubular sclerosis].
abstract: Tubular sclerosis is a pulp-dentin complex defensive response to several physiologic and pathologic stimuli; it leads to an increasing tubular obliteration which enormously reduces dentinal permeability. Its typical structural features are either increased peritubular dentin thickness or "caries crystals". Pathogenesis is a much debated question: some authors assert that peritubular dentin thickening is the main liable for sclerosis while others support a centrifugal theory. Another point of view considers its pathogenesis the result of many integrated mechanism.
authors.affiliation: Istituto di Odonto-Gnato-Stomatologia, Università degli Studi di Firenze.
authors.forename: L
authors.initials: L
authors.lastname: Lillo
authors.forename: F
authors.initials: F
authors.lastname: Pierleoni
authors.forename: G
authors.initials: G
authors.lastname: Pagavino
mesh_terms: D001031:Apatites / Q000378:metabolism; D002114:Calcinosis / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D003461:Crystallography; D003809:Dentin, Secondary / Q000378:metabolism / Q000648:ultrastructure*; D006801:Humans; D009804:Odontoblasts / Q000378:metabolism / Q000473:pathology
chemical_list: D001031:Apatites
vernacular_title: In tema di sclerosi tubulare.