[Structural typology assay of principal anticancer agents on the basis of molecular fragmentation].
The developed formula of 58 anticancer agents used in therapeutic or still in clinical essays were treated by molecular connectivity matrix method. This technic allows the search and the automatically count of structural fragments of the different studied molecules. Then it has been possible to build a spanning tree (Prim's arborescent skeleton) which gathers the different molecules and permits to put a priori new structures.
Viel
C
C
Faculté de Pharmacie, Tours.
Lacroix
J
J
Lacroix
R
R
Doré
J C
JC
D000970:Antineoplastic Agents / Q000737:chemistry* / Q000145:classification; D001330:Electronic Data Processing; D066298:In Vitro Techniques; D008967:Molecular Biology; D013008:Somatotypes
D000970:Antineoplastic Agents
Essai de typologie structurale des principaux anticancéreux sur la base d'une fragmentation moléculaire.