[The growth and metastatic characteristics of Lewis lung carcinoma during reproductive dysfunction in male C57BL/6 mice].
Results of a study of the pattern of spontaneous dissemination of Lewis lung carcinoma in male mice with reproductive system dysfunction showed that removal of the gonads followed by substitution treatment with testosterone failed to influence tumor metastatic potential. The data suggested that the androgen lacked a modulating effect on growth and dissemination of Lewis lung carcinoma.
Mikhaĭlevskaia
L L
LL
Galochkina
Z I
ZI
Koroleva
A M
AM
Shumova
S L
SL
Kinzirskiĭ
A S
AS
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000473:pathology*; D007279:Injections, Subcutaneous; D008175:Lung Neoplasms / Q000097:blood / Q000473:pathology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009362:Neoplasm Metastasis; D009919:Orchiectomy; D013737:Testis / Q000502:physiology*; D013739:Testosterone / Q000008:administration & dosage; D013997:Time Factors
D013739:Testosterone
Kharakteristika rosta i metastazirovaniia kartsinomy legkogo L'iuis v usloviiakh disfunktsii reproduktivnoĭ sistemy mysheĭ samtsov B57BL/6.