[Comparison between nuclear DNA and histologic grade of prostatic carcinoma].
DNA nuclear ploidy determined by flow cytometry was evaluated from prostate tissue in 51 patients with prostatic cancer who had undergone radical prostatectomy. DNA ploidy pattern was diploid in 46% and aneuploid in 54% of tumors. DNA ploidy was compared to histological tumor grading. 92 Aneuploidy was found in 0% of the tumors with Gleason score between 2 and 4 in 62% between 5 and 7 and in 50% between 8 and 10. Our results suggest there is no relationship between the two parameters.
Zattoni
F
F
Institut d'Urologie, Université de Padova, Italie.
Prayer Galetti
T
T
Vianello
F
F
Bertoldin
R
R
Panozzo
M
M
Blandamura
S
S
Costantin
G
G
D000368:Aged; D002277:Carcinoma / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D004273:DNA, Neoplasm / Q000032:analysis*; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000276:immunology; D011471:Prostatic Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies
D004273:DNA, Neoplasm; D017430:Prostate-Specific Antigen
Comparaison entre ADN nucléaire et grade histologique du carcinome prostatique.