title: [Benign polypoid lesions of the gallbladder. Their relation to gallbladder adenocarcinoma].
abstract: Out of 12,153 cholecystectomies performed over a period of 10 years, 114 polypoid lesions were found in 81 removed gallbladders (0.7%). 225 adenocarcinomas of the gallbladder were found in the same population (1.85%). The mean age of patients with polypoid lesions was 46 years, with a male to female ratio of 1:2.7. 94% of lesions measured less than 10 mm and only 9.6% were adenomas. Among these, dysplastic alterations were found in all and one had evidence of early adenocarcinoma. The mean age of patients with adenocarcinoma was 62 years with a male to female ratio of 1:6. Residual adenomas were found in 2 cases and multiple adenomas coexisted in another case. Thus, polypoid lesions of the gallbladder are less frequent than adenocarcinoma. Only adenomas show a potential to evolve to malignant lesions, but their low incidence makes them an unimportant precursor of gallbladder carcinoma.
authors.affiliation: Instituto de Anatomía Patológica, Hospital Clínico de la Universidad de Chile, Santiago.
authors.forename: G
authors.initials: G
authors.lastname: Smok
authors.forename: R
authors.initials: R
authors.lastname: Bentjerodt
authors.forename: A
authors.initials: A
authors.lastname: Csendes
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology* / Q000473:pathology; D000328:Adult; D000368:Aged; D002677:Chile / Q000453:epidemiology; D002763:Cholecystectomy; D005260:Female; D005706:Gallbladder Neoplasms / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011127:Polyps / Q000453:epidemiology* / Q000473:pathology
vernacular_title: Lesiones polipoídeas benignas de la vesicula biliar. Relación con adenocarcinoma vesicular.