title: [Resurgence of yaws in Central African Republic. Role of the Pygmy population as a reservoir of the virus].
abstract: The authors present the results of a clinical (framboesia) and serological (TPHA and VDRL) investigation aimed at defining the reservoir of virus of yaws in the Lobaye area (southwest of CAR) out of which the disease spreads in spite of previous mass treatment campaigns. The Lobaye focus is still active because we found among the pediatric population under the age of 15 years, 5.6% contagious skin lesion and 19.6% VDRL+. In this area with contact between nomadic Pygmies and sedentary ethnic groups, the observed level of clinical and serological attacks suggested that the pygmie population, as previously described, makes up the principal focus of yaws. For every 1 case found through clinical examination, 3.5 cases VDRL+ and 4.8 cases TPHA+ are found through serological examination. This proportion indicates that clinical screening alone is not sufficient to evaluate the endemic yaws level in a population.
authors.affiliation: Institut Pasteur, Bangui, République centrafricaine.
authors.forename: V
authors.initials: V
authors.lastname: Hervé
authors.forename: E
authors.initials: E
authors.lastname: Kassa Kelembho
authors.forename: P
authors.initials: P
authors.lastname: Normand
authors.forename: A
authors.initials: A
authors.lastname: Georges
authors.forename: C
authors.initials: C
authors.lastname: Mathiot
authors.forename: P
authors.initials: P
authors.lastname: Martin
mesh_terms: D000293:Adolescent; D002488:Central African Republic; D002648:Child; D002675:Child, Preschool; D004197:Disease Reservoirs; D006386:Hemagglutination Tests; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D014210:Treponema pallidum / Q000302:isolation & purification; D015001:Yaws / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission*
vernacular_title: Résurgence du pian en République centrafricaine. Rôle de la population pygmée comme réservoir de virus.