[The effect of pentagastrin and substance P on the gastric parietal glandulocytes].
Investigations on dogs show that substance P suppresses pentagastrin gastric acid secretion. This effect is abolished by acetylcholinesterase block by calimin. The results indicate that pentagastrin and substance P participate in cholinergic regulation of gastric acid secretion.
Korshak
A L
AL
Kotsiuba
V L
VL
Rybal'chenko
V K
VK
D000818:Animals; D002800:Cholinesterase Inhibitors / Q000494:pharmacology; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005745:Gastric Acidity Determination; D005750:Gastric Juice / Q000187:drug effects / Q000378:metabolism; D010295:Parietal Cells, Gastric / Q000187:drug effects* / Q000378:metabolism; D010418:Pentagastrin / Q000494:pharmacology*; D011729:Pyridostigmine Bromide; D013373:Substance P / Q000494:pharmacology*
D002800:Cholinesterase Inhibitors; D013373:Substance P; D010418:Pentagastrin; D011729:Pyridostigmine Bromide
Vliianie pentagastrina i substantsii P na parietal'nye glandulotsity zheludka.