[Subjective complaints and hormonal reactions in the first 6 weeks after hysterectomy].
Hormone profiles (estradiol, testosterone, FSH, LH) and typical estradiol deficiency phenomena were investigated prospectively in the first 6 weeks after hysterectomy (n = 50) and after additional bilateral adnexectomy (n = 17). In the second group estradiol was replaced transdermally from the 2nd postoperative day (estradiol patch, 0.05 mg daily). In the 1st group 34% of patients showed a significant decrease in estradiol, 28% of patients a significant decrease in testosterone on the 3rd postoperative day which was no longer demonstrable after 6 weeks. In the second group no decrease in hormone levels was found. So the estradiol patch can replace estradiol to a sufficient degree and in particular physiologically even after bilateral oophorectomy Subjective complaints improved in both groups. Psychosomatic influence also seems to be of importance.
Schmitt-Robe
B
B
Frauenklinik am Diakonissenkrankenhaus Mannheim Lehrkrankenhaus der Universität Heidelberg.
Eicher
W
W
Mück
A O
AO
Klinga
K
K
D000328:Adult; D003687:Dehydroepiandrosterone / Q000031:analogs & derivatives / Q000097:blood; D019314:Dehydroepiandrosterone Sulfate; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D007044:Hysterectomy; D007986:Luteinizing Hormone / Q000097:blood; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood / Q000601:surgery*; D010052:Ovariectomy; D011183:Postoperative Complications / Q000097:blood*; D011446:Prospective Studies; D013739:Testosterone / Q000097:blood; D014591:Uterine Diseases / Q000097:blood / Q000601:surgery*; D014594:Uterine Neoplasms / Q000097:blood / Q000601:surgery*
D012739:Gonadal Steroid Hormones; D013739:Testosterone; D003687:Dehydroepiandrosterone; D004958:Estradiol; D019314:Dehydroepiandrosterone Sulfate; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Subjektive Beschwerden und hormonelle Reaktionen in den ersten 6 Wochen nach Hysterektomie.