Electrophysiological study on jaw-opening reflex recorded from digastric muscle in Parkinson's disease and primary cranial dystonias.
We investigated digastric reflex excitability in normals and in patients with extrapyramidal disorders such as primary cranial dystonias and Parkinson's disease. Relationships between exteroceptive suppression of masseter muscle and digastric reflex were also investigated in some cases. Digastric reflex hyperexcitability was observed in dystonic patients when compared to normals and parkinsonian patients. Furthermore, some patients with cranial dystonia presented absence of exteroceptive suppression reflex in masseter muscle with enlarged digastric response. These results indicate hyperexcitability of the digastric reflex and abnormal agonist-antagonist muscle co-contraction in chewing reflexes of patients with cranial dystonias. This shows that digastric reflex is an important electrophysiological investigation to explore the physiopathological mechanisms of primary cranial dystonias.
Alfonsi
E
E
Service of Clinical Neurophysiology, IRCCS C. Mondino, University of Pavia, Italy.
Pacchetti
C
C
Lozza
A
A
Conti
R
R
Martignoni
E
E
Bruggi
P
P
Sandrini
G
G
Arrigo
A
A
Moglia
A
A
D000368:Aged; D001480:Basal Ganglia Diseases / Q000503:physiopathology*; D004421:Dystonia / Q000503:physiopathology*; D004558:Electric Stimulation; D004576:Electromyography; D005260:Female; D006801:Humans; D007568:Jaw / Q000294:innervation*; D008297:Male; D008538:Meige Syndrome / Q000503:physiopathology; D008875:Middle Aged; D009334:Neck Muscles / Q000294:innervation*; D010300:Parkinson Disease / Q000503:physiopathology*; D012026:Reflex, Stretch / Q000502:physiology*; D014103:Torticollis / Q000503:physiopathology; D014276:Trigeminal Nerve / Q000503:physiopathology