Colchicine treatment in conception and pregnancy: two hundred thirty-one pregnancies in patients with familial Mediterranean fever.
The effect of maternal use of colchicine on fetuses is unknown. The children of 116 women with Familial Mediterranean Fever (225 completed pregnancies) were studied. There was no unusual frequency of fetal abnormality among women taking colchicine before or during pregnancy. Colchicine treatment does not apparently harm mother or child.
Rabinovitch
O
O
Department of Gynecology and Obstetrics, Sheba Medical Center, Tel-Aviv University Medical School, Israel.
Zemer
D
D
Kukia
E
E
Sohar
E
E
Mashiach
S
S
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000022:Abortion, Spontaneous / Q000453:epidemiology; D002585:Cesarean Section / Q000706:statistics & numerical data; D003078:Colchicine / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D010505:Familial Mediterranean Fever / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011256:Pregnancy Outcome / Q000453:epidemiology
D003078:Colchicine