title: The antimicrobial activity of non-antibiotics: interactions with antibiotics.
abstract: The following are considered: the direct antibacterial activity of non-antibiotics: resistance-reversing agents and resistance-inducing agents; the antibacterial and antiparasitic activity of non-antibiotics: psychotropics, antihistaminics, antineoplastics, allopurinol, hyperbaric oxygen, etc.; as well as the antibacterial activity of agents modifying the urinary pH; the influence of non-antibiotic drugs on the pharmacokinetic parameters of antibiotics; the anti infectious activity of non-antibiotics through their effects on host defences, immunity and inflammation, and finally the use of non-antibiotics to decrease the toxicity of anti-infectious agents.
authors.affiliation: Hôpital Cochin, Hepato-gastro-enterology Dpt., Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Neuman
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001711:Biotransformation / Q000187:drug effects; D004352:Drug Resistance, Microbial; D004357:Drug Synergism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007109:Immunity / Q000187:drug effects; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents