title: [Prospective epidemiological study on the efficacy and safety of female tubal sterilization by chemical instillation].
abstract: This is a prospective study on clinical efficacy and safety of female sterilization by chemical agents. A total number of 1705 subjects were randomly divided into two groups. Phenol mucilage (PM) was used in group 1 (834 cases) and phenol-atabrine paste (PAP) was used in group 2 (871 cases). All the characteristics of the subjects were proportionate and comparable to two groups. The follow-up rate was 98.5% at the end of 2 years. Using life table analysis, the results show that the cumulative success rate per 100 women of two groups using PAP and PM was 97.4% and 91.1% respectively. There was significant difference between the two groups. The efficacy of the methods was related with the developed length of roentgenographic shadow after instillation. Multiple discriminatory analysis showed the same results as above. There was no severe complication in all cases. The post-instillation fever rate was 8% in group PAP and 4.4% in group PM, respectively. Our results indicate that female sterilization with the use of chemical agents mentioned is a simple, safe and reliable method in preventing pregnancy.
authors.affiliation: National Research Institute for Family Planning, Beijimg.
authors.forename: Y
authors.initials: Y
authors.lastname: Liu
mesh_terms: D015331:Cohort Studies; D005260:Female; D006801:Humans; D015993:Life Tables; D010636:Phenols / Q000008:administration & dosage; D011446:Prospective Studies; D013246:Sterilization, Tubal / Q000379:methods* / Q000706:statistics & numerical data
chemical_list: D010636:Phenols