title: [Administration of metoprolol in refractory and severe heart failure].
abstract: METHODS
  46 cases of severe heart failure refractory to digitalis glycosides, diuretics and/or vasodilators were studied.
  
  
  METHODS
  First dose of beta-loc (metoprolol) was 6.25 mg twice a day. If no untoward effects, according to patient's condition, the dose was gradually increased to 12.5-25 mg b.i.d. for 4-6 weeks.
  
  
  RESULTS
  Of the total 46 cases, improvement was found in 44, among which 23 cases (50%) were excellent and 21 cases (46%) fine. The effective rate reached 96%, which was very satisfactory.
authors.affiliation: Xiamen First Hospital.
authors.forename: J
authors.initials: J
authors.lastname: Huang
mesh_terms: D000328:Adult; D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000150:complications; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008790:Metoprolol / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D012214:Rheumatic Heart Disease / Q000150:complications
chemical_list: D008790:Metoprolol