[The modification of a radiation lesion in animals with an aqueous extract of Hypericum perforatum L. 2].
The preparation Hypericum perforatum L. has been shown to decrease the intensity level of enzymatic and non-enzymatic processes of lipid peroxidation of rat liver microsomes in vitro and in vivo. In the mucus of the this intestine in vivo the increase of the number of non-enzymatic SH-groups is observed. Possible mechanisms of radioprotective action of the preparation is under discussion.
Smyshliaeva
A V
AV
Nguyen
L H
LH
Kudriashov
Iu B
IuB
D000818:Animals; D004353:Drug Evaluation, Preclinical; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism; D007421:Intestine, Small / Q000187:drug effects / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000627:therapeutic use*; D011833:Radiation Injuries, Experimental / Q000188:drug therapy / Q000378:metabolism / Q000517:prevention & control*; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000187:drug effects / Q000378:metabolism; D013997:Time Factors
D010936:Plant Extracts; D011837:Radiation-Protective Agents
Modifikatsiia luchevogo porazheniia zhivotnykh vodnym ékstraktom Hypericum perforatum L. Soobshchenie 2.