title: Obstructive solitary bronchial non-Hodgkin's lymphoma--a rare presentation of primary extranodal disease.
abstract: Endobronchial involvement by non-Hodgkin's lymphoma (NHL) is uncommon and usually occurs in the presence of more generalised disease. Solitary endobronchial lymphoma in the absence of disease elsewhere is extremely rare. In this report we describe a patient with an obstructing endobronchial mass which was the initial manifestation of NHL. The patient was treated initially with radiotherapy followed by cyclic combination chemotherapy with initial complete resolution of the endobronchial disease. However, he subsequently developed widespread lymphoma. This unusual presentation of NHL is discussed and the relevant literature is reviewed.
authors.affiliation: Institute of Pulmonology, Hadassah University Hospital, Jerusalem, Israel.
authors.forename: N
authors.initials: N
authors.lastname: Berkman
authors.forename: J
authors.initials: J
authors.lastname: Lafair
authors.forename: E
authors.initials: E
authors.lastname: Okon
authors.forename: A
authors.initials: A
authors.lastname: Polliack
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001984:Bronchial Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D016898:Interferon-alpha / Q000627:therapeutic use; D008224:Lymphoma, Follicular / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D016403:Lymphoma, Large B-Cell, Diffuse / Q000188:drug therapy / Q000628:therapy; D008297:Male; D016609:Neoplasms, Second Primary; D011241:Prednisone / Q000008:administration & dosage; D012074:Remission Induction; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D007155:Immunologic Factors; D016898:Interferon-alpha; D014750:Vincristine; D003520:Cyclophosphamide; D011241:Prednisone