[Visual function damage in primary open angle glaucoma (POAG) in relation to hemorheology, ocular rheograph and other factors].
Researches of glaucomatous visual damage, hemorheology, ocular rheograph and other multiplex factors, with computed multifactorial stepwise regression analysis, indicate that elevation of intraocular pressure (IOP) is not the only factor to induce visual impairment. POAG patients are shown to have markedly reduced diastolic perfusion pressure in the ophthalmic artery, besides prolonged filling time of the retinal artery and vein, diminished erythrocyte deformability and increased platelet adhesion rate. The characteristic ocular rheographic changes in POAG patients of controlled IOP suggest that hemorheological factors play a role in the visual function damage.
Ge
J
J
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou.
D000328:Adult; D004907:Erythrocyte Deformability; D005260:Female; D005902:Glaucoma, Open-Angle / Q000097:blood* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D009898:Optic Disk; D010973:Platelet Adhesiveness; D010992:Plethysmography, Impedance; D012044:Regression Analysis; D012212:Rheology; D014785:Vision, Ocular / Q000502:physiology*