[Polyarthritis revealing hairy cell leukemia].
A female patient simultaneously developed hematologic evidence of hairy cell leukemia and marked but short-lived inflammatory involvement of a number of joints. Both these groups of symptoms resolved simultaneously and rapidly under alpha-2 interferon therapy. This course suggests that the arthritis was a rheumatologic manifestation of the hematologic disease. The concomitant occurrence in this patient of arthritis, splenomegaly and leukopenia was suggestive of Felty syndrome: these two conditions need to be differentiated.
L'Hirondel
J L
JL
Service de Rhumatologie, CHRU Côte de Nacre, Caen.
Troussard
X
X
Macro
M
M
Courtheoux
F
F
Guaydier-Souquières
G
G
Mandard
J C
JC
Loyau
G
G
D000328:Adult; D001168:Arthritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003937:Diagnosis, Differential; D005258:Felty Syndrome / Q000175:diagnosis; D005260:Female; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use; D007943:Leukemia, Hairy Cell / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D009503:Neutropenia / Q000150:complications; D011994:Recombinant Proteins; D013163:Splenomegaly / Q000150:complications
D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins
Polyarthrite révélatrice d'une leucémie à tricholeucocytes.