[Changes in spirometric values induced by nasally administered beclomethasone dipropionate in patients with perennial allergic rhinitis].
Authors showed that it's possible to control the asthmatic component in patients with persistent allergical rhinitis without bronchodilatory drugs. AA. compared two groups of ten patients: Group A has been treated with antihystaminical drugs or ketotifen per os and Disodium chromoglycate per nasal spray, Group B has been treated with the same drugs and Beclomethasone Dipropionate per nasal spray more (400 mcg a day). Respiratory functionality tests (FEV1 and MEF75) have been carried out at the beginning and at the end of the trial and the subsequent clinical parameters have been considered: dispnoea attacks, rhinorrhaea, sneezes, lost working or school days. The results of the study showed after three months of therapy a statistically significant improvement of FEV1 and MEF75 in Group B only; moreover the patients of the Group B had lower number of asthmatic attacks then patients of the Group A.
Bilancia
R
R
Cattedra di Malattie dell'Apparato Respiratorio, Università degli Studi di Bari.
Federici
F
F
Ricatti
D G
DG
Buonpensiere
L
L
Ferrannini
A
A
Gramiccioni
E
E
D000280:Administration, Inhalation; D000293:Adolescent; D000328:Adult; D001507:Beclomethasone / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy* / Q000503:physiopathology; D013147:Spirometry
D001507:Beclomethasone
Modificazione dei valori spirometrici indotti dal beclometasone dipropionato per via nasale in pazienti con rinite allergica perenne.