title: [The histological evaluation of the effect of Bacillus intermedius RNAse on the organs of immunogenesis in laboratory animals].
abstract: Histological changes in organs of immunogenesis of experimental animals after RNAse Bacillus intermedius treatment have been studied. The effect of RNAse on organs is revealed in activation of both cell and humoral immunity and factors of nonspecific resistance at early stage of reaction. The inhibition of immunological reactions and factors of nonspecific resistance takes place at later stages of enzyme action. The caused effects don't depend on catalytic enzyme activity.
authors.forename: Z M
authors.initials: ZM
authors.lastname: Nekhoroshkova
authors.forename: D E
authors.initials: DE
authors.lastname: Tsyplakov
authors.forename: A V
authors.initials: AV
authors.lastname: Tsyplakova
authors.forename: B M
authors.initials: BM
authors.lastname: Kurinenko
mesh_terms: D000818:Animals; D001407:Bacillus / Q000201:enzymology*; D008198:Lymph Nodes / Q000033:anatomy & histology / Q000187:drug effects* / Q000276:immunology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D012260:Ribonucleases / Q000494:pharmacology*; D013154:Spleen / Q000033:anatomy & histology / Q000187:drug effects* / Q000276:immunology; D013950:Thymus Gland / Q000033:anatomy & histology / Q000187:drug effects* / Q000276:immunology; D013997:Time Factors
chemical_list: D012260:Ribonucleases
vernacular_title: Gistologicheskaia otsenka vliianiia RNKazy Bacillus intermedius na organy immunogeneza laboratornykh zhivotnykh.