title: Assessment of the lifetime accumulated cadmium intake from food in Kempenland.
abstract: Research in 1984 indicated that the cadmium body burden was higher in a village where the soil is contaminated with cadmium (Luyksgestel) than in a control village (Zeeland). The distribution of kidney function parameters also differed between the two villages. The aim of this study is to estimate the lifetime accumulated cadmium intake from food for the people from both villages. Various data sets describing dietary patterns in the Netherlands were used. The assessed average lifetime accumulated cadmium intake from food by the study subjects (aged 30-69 years) was 435 mg (+/- 131 mg) in Luyksgestel and 394 (+/- 113 mg) in Zeeland. The estimated lifetime accumulated cadmium intake for a hypothetical allotment gardener of 55 years was 520 mg from vegetables grown on uncontaminated soil, and 655 mg for lifelong consumption of vegetables from contaminated soil. The Luyksgestel subjects' estimated cadmium intake from food was well below the provisional tolerable weekly intake as proposed by the WHO, of 400-500 micrograms or 1124-1404 mg for the lifelong intake by a 55-year-old man.
authors.affiliation: National Institute of Public Health and Environmental Protection, Department of Epidemiology, Bilthoven, The Netherlands.
authors.forename: I A
authors.initials: IA
authors.lastname: Kreis
authors.forename: A
authors.initials: A
authors.lastname: Wijga
authors.forename: J H
authors.initials: JH
authors.lastname: van Wijnen
mesh_terms: D000328:Adult; D000368:Aged; D001822:Body Burden; D002104:Cadmium / Q000008:administration & dosage / Q000032:analysis / Q000493:pharmacokinetics* / Q000652:urine; D004435:Eating; D004781:Environmental Exposure / Q000032:analysis; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D012907:Smoking; D012989:Soil Pollutants / Q000032:analysis; D014675:Vegetables / Q000737:chemistry*
chemical_list: D012989:Soil Pollutants; D002104:Cadmium