title: Influence of a natural-ingredient diet containing Phaseolus vulgaris on the colonization by segmented, filamentous bacteria of the small bowel of mice.
abstract: The appearance of segmented, filamentous bacteria (SFBs) in the small bowel of mice is influenced by the composition of the diet, but the dietary components responsible are not known. The addition of ground, whole Phaseolus vulgaris to a natural-ingredient diet at the expense of part of the skim milk powder, ground barley and wheat middlings components, caused an increase of the colonization of the mouse small bowel by SFBs. This effect was not seen when whole Phaseolus was added to a purified diet at the expense of part of the casein, corn oil, coconut fat, corn starch, dextrose and cellulose components. In an attempt to identify the fraction of Phaseolus that might contain SFB-inducing substances, the skin and kernel fraction of the bean were added to the natural-ingredient diet. The skin and kernel fraction were found to be as effective in inducing SFB appearance as was whole Phaseolus.
authors.affiliation: Central Animal Laboratory, Catholic University, Nijmegen, The Netherlands.
authors.forename: H L
authors.initials: HL
authors.lastname: Klaasen
authors.forename: J P
authors.initials: JP
authors.lastname: Koopman
authors.forename: M E
authors.initials: ME
authors.lastname: van den Brink
authors.forename: M H
authors.initials: MH
authors.lastname: Bakker
authors.forename: A C
authors.initials: AC
authors.lastname: Beynen
mesh_terms: D000821:Animal Feed; D000818:Animals; D001419:Bacteria / Q000254:growth & development* / Q000302:isolation & purification; D001685:Biological Factors / Q000032:analysis; D015169:Colony Count, Microbial; D007887:Fabaceae; D005260:Female; D007421:Intestine, Small / Q000382:microbiology*; D051379:Mice; D010946:Plants, Medicinal; D015203:Reproducibility of Results
chemical_list: D001685:Biological Factors