[Anti-inflammatory and analgesic actions of artificial and fermentative Ganoderma sinense (AFGS)].
Both AFGS and natural Ganoderma sinense (NGS) have obvious anti-inflammatory and analgesic effects for arthritis in rats induced by carrageenan and the pain reaction in mice induced by hot scalding as well as HAC-induced writhing. AFGS also can reduce the edematous swelling of mice's ears, reduce the capillary permeability of mice skin and obviously inhibit cotton pellets granuloma implanted in rats. It can promote cytophagy capacity of the reticular endothelial cells in mice. No irritation on the gastric mucosa in rats has been observed.
Wan
F
F
Jiangxi Institute of Materia Medica, Nanchang.
Huang
D
D
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology* / Q000627:therapeutic use; D001169:Arthritis, Experimental / Q000139:chemically induced / Q000188:drug therapy*; D002199:Capillary Permeability / Q000187:drug effects; D002351:Carrageenan; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D015745:Granuloma, Foreign-Body / Q000188:drug therapy; D008297:Male; D051379:Mice; D017288:Pain Threshold / Q000187:drug effects*; D010587:Phagocytosis / Q000187:drug effects; D011124:Polyporaceae; D051381:Rats; D017208:Rats, Wistar
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004365:Drugs, Chinese Herbal; D002351:Carrageenan