[The effect of convaflavin on lipid peroxidation in the heart in experimental thyrotoxicosis].
The effect of convaflavin in doses of 30 and 45 mg/kg on lipid peroxidation in the heart was studied in white rats with experimental thyrotoxicosis. A noticeable decrease of the concentration of diene conjugates and malonic dialdehyde was revealed as was activation of catalase and peroxidase under the influence of convaflavin administered in a dose of 45 mg/kg.
Vadziuk
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D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology*; D013956:Antithyroid Agents; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D006321:Heart / Q000187:drug effects*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D013963:Thyroid Hormones; D013971:Thyrotoxicosis / Q000139:chemically induced / Q000188:drug therapy* / Q000378:metabolism
D000975:Antioxidants; D013956:Antithyroid Agents; D013963:Thyroid Hormones; C004227:thyroidin
Vliianie konvaflavina na perekisnoe okislenie lipidov v serdtse pri éksperimental'nom tireotokiskoze.