title: Determinants of outcome in sporadic nontoxic goiter.
abstract: The author points out that natural history of sporadic nontoxic goiter (SNG) is characterized by increasing thyroid volume, nodularity and autonomy of function leading to hyperthyroidism in 13-16% of the patients after a medium follow-up of circa 12 years. Successively, the author reports and discusses the effectiveness and the outcome of the therapeutical modalities used for SNG: thyroidectomy, thyroid hormones and radioactive iodine.
authors.affiliation: Department of Endocrinology, Academic Medical Center, University of Amsterdam, The Netherlands.
authors.forename: W M
authors.initials: WM
authors.lastname: Wiersinga
mesh_terms: D006042:Goiter / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D012008:Recurrence; D013963:Thyroid Hormones / Q000627:therapeutic use; D013965:Thyroidectomy; D016896:Treatment Outcome
chemical_list: D007457:Iodine Radioisotopes; D013963:Thyroid Hormones