title: [Projections from lamina V of the cerebral cortex to the dorsomedial thalamic nucleus and neighboring nuclei].
abstract: The laminar projections from the cerebral cortex to the mediodorsal thalamic nucleus and adjacent thalamic nuclei were studied by means of the horseradish peroxidase (HRP) retrograde axonal transport method. A possible correlation was found between the connectivity arising from layer V of the cerebral cortex, and the rich-acetylcholinesterase (AChE) regions within the subcortical structures under study. This suggests the possibility that layer V of the cerebral cortex in Alzheimer's disease is initially affected and subsequently those rich-AChE subcortical regions with which it is connected.
authors.affiliation: Departamento de Morfología, Facultad de Medicina, Universidad Autónoma de Madrid, España.
authors.forename: J L
authors.initials: JL
authors.lastname: Velayos
authors.forename: E
authors.initials: E
authors.lastname: Mengual
mesh_terms: D000110:Acetylcholinesterase / Q000032:analysis; D000818:Animals; D001370:Axonal Transport; D002415:Cats; D002540:Cerebral Cortex / Q000033:anatomy & histology* / Q000201:enzymology; D004525:Efferent Pathways / Q000033:anatomy & histology / Q000737:chemistry; D006735:Horseradish Peroxidase; D009419:Nerve Tissue Proteins / Q000032:analysis; D013787:Thalamic Nuclei / Q000033:anatomy & histology* / Q000737:chemistry
chemical_list: D009419:Nerve Tissue Proteins; D006735:Horseradish Peroxidase; D000110:Acetylcholinesterase
vernacular_title: Proyecciones de la lámina V de la corteza cerebral al núcleo dorsomedial del tálamo y núcleos vecinos.