[The clinical significance of membrane-destructive processes and their correction in children with suppurative surgical infection].
The results of examination of 101 patients with purulent surgical infection provide evidence of considerable disorders of cell membrane metabolism which correspond to the severity of the disease. Three states of the antioxidant defence system were distinguished: compensated, subcompensated, and decompensated. It is suggested that antioxidant and membrane-stimulating treatment should be applied with consideration for the types of the course followed by the metabolic processes (metabolically latent, lipoperoxidatative, and peroxidative). The clinical effect of the use of antioxidants in 38 patients is shown.
Matskevich
B I
BI
Koval'chuk
V I
VI
D000038:Abscess / Q000097:blood* / Q000188:drug therapy / Q000601:surgery; D000975:Antioxidants / Q000627:therapeutic use; D002481:Cellulitis / Q000097:blood* / Q000188:drug therapy / Q000601:surgery; D002648:Child; D003131:Combined Modality Therapy; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000378:metabolism; D005609:Free Radicals; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood; D008055:Lipids / Q000097:blood; D008199:Lymphadenitis / Q000097:blood* / Q000188:drug therapy / Q000601:surgery; D012874:Skin Diseases, Infectious / Q000097:blood* / Q000188:drug therapy / Q000601:surgery
D000975:Antioxidants; D005609:Free Radicals; D008054:Lipid Peroxides; D008055:Lipids
Klinicheskoe znachenie membranodestruktivnykh protsessov i ikh korrektsiia u deteĭ s gnoĭnoĭ khirurgicheskoĭ infektsieĭ.