title: Intraocular manifestations of systemic sarcoidosis.
abstract: The incidence of intraocular manifestations was studied in 159 patients with systemic sarcoidosis. Eighty-seven patients (54.7%) who presented ocular lesions suggestive of sarcoidosis as an initial manifestation were diagnosed after a systemic survey. Seventy-two patients (45.3%) had chest signs or symptoms and were referred to ophthalmic examination during a diagnostic survey. Of the 159 patients, 126 (79.2%) showed intraocular involvements at diagnosis. In these patients with ocular involvements, iritis was the most frequent lesion, being seen in 74.7%. Gonioscopic examinations revealed trabecular nodules and tent-like peripheral anterior synechia in 61.2 and 54.5% of the patients respectively. Retinal perivasculitis and spotty retinochoroidal exudates were seen in 67.3 and 53.9% of the patients respectively. The data indicated the presence of intraocular lesions in a significant number of patients with sarcoidosis. These findings emphasize that all patients with systemic sarcoidosis need a thorough eye examination. This ocular examination should include gonioscopy.
authors.affiliation: Department of Ophthalmology, Jichi Medical School, Tochigi, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ohara
authors.forename: A
authors.initials: A
authors.lastname: Okubo
authors.forename: H
authors.initials: H
authors.lastname: Sasaki
authors.forename: K
authors.initials: K
authors.lastname: Kamata
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000869:Anterior Eye Segment / Q000473:pathology; D005128:Eye Diseases / Q000175:diagnosis*; D005260:Female; D006068:Gonioscopy; D006801:Humans; D015994:Incidence; D007500:Iritis / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D012507:Sarcoidosis / Q000175:diagnosis*; D014129:Trabecular Meshwork / Q000473:pathology