title: Quantitative analysis of visual acuity through amber discolored lenses.
abstract: Discoloration of hydrogel contact lenses is frequently encountered in clinical practice and often precipitates lens replacement. This investigation sought to determine if lens discoloration was associated with a compromise in low or high contrast, high illumination visual acuity. This association would lead to a more scientific rationale for lens replacement. Amber lens discoloration was achieved using human-worn 55% water hydrophilic contact lenses (Methafilcon-A) heated in a 1% potassium sorbate, low pH saline solution. A spectrum of 6 discolored lenses was obtained with a peak absorbance at 320 nm. Fifteen subjects, between the ages of 22 and 38 years, were tested wearing each of the discolored lenses. None of the differences in high or low contrast acuity between our discolored and nondiscolored lenses were found to be statistically significant using a paired t-test at the 99% significance level.
authors.affiliation: Contact Lens Research Group, State College of Optometry, State University of New York, New York.
authors.forename: R E
authors.initials: RE
authors.lastname: Gundel
authors.forename: E N
authors.initials: EN
authors.lastname: Kaplan
authors.forename: J S
authors.initials: JS
authors.lastname: Rosen
mesh_terms: D000328:Adult; D003116:Color; D003263:Contact Lenses, Hydrophilic; D015350:Contrast Sensitivity / Q000502:physiology; D004311:Double-Blind Method; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D055095:Optics and Photonics; D011092:Polyethylene Glycols; D014792:Visual Acuity / Q000502:physiology*
chemical_list: D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011092:Polyethylene Glycols