title: [Extramedullary blast transformation in chronic granulocytic leukemia].
abstract: A patient with Ph1(Philadelphia chromosome) positive chronic granulocytic leukemia and extramedullary blast transformation (crisis) in lymph nodes of neck and axillae which appeared after 4-year of treatment with busulfan is presented. Biopsy of lymph node and histopathological examination showed lymphoblastic infiltration. The patient was treated with radiotherapy and chemotherapy with protocol COP. He survived 7 months and expired due to renal insufficiency.
authors.affiliation: Institute of Haematology, University Clinical Centre, Belgrade.
authors.forename: A
authors.initials: A
authors.lastname: Vidović
authors.forename: G
authors.initials: G
authors.lastname: Janković
authors.forename: N
authors.initials: N
authors.lastname: Suvajdzić
authors.forename: M
authors.initials: M
authors.lastname: Colović
mesh_terms: D001752:Blast Crisis; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010677:Philadelphia Chromosome
vernacular_title: Ekstramedulski blastni preobrazaj u hronicnoj granulocitnoj leukemiji.