[Effects of Salvia miltiorrhiza Bunge on isolated perfused liver and portal vein of rats].
The experiment results showed that Salvia miltiorrhiza (SMB) had a protective effect on the isolated perfused liver injured by CCl4 of rats, made the activity of GPT in perfusate of SMB group lower than that of intoxicated groups and relieved the hepato-pathohistologic lesions of SMB group as compared to the intoxicated group. SMB had no significant effects on both the activities of SGPT in vitro and the portal vein of rats.
Yu
Z P
ZP
Yunnan Traditional Chinese Medicine, Kunming.
Jiang
J X
JX
Zhu
L H
LH
Li
Z
Z
Guo
X H
XH
D000410:Alanine Transaminase / Q000378:metabolism; D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy* / Q000209:etiology; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000473:pathology*; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000187:drug effects*; D010477:Perfusion; D010936:Plant Extracts; D011169:Portal Vein / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D027561:Salvia miltiorrhiza
D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; D000410:Alanine Transaminase