[Lupus, sicca syndrome and chronic interstitial nephritis. Apropos of a case].
A female patient from the French Antilles developed renal failure due to pure chronic interstitial nephritis six months after the onset of systemic lupus erythematosus (SLE) for which she was taking hydroxychloroquine. Over time, results of biologic tests became suggestive of concomitant Gougerot-Sjögren syndrome, but neither the clinical nor the histologic findings were consistent with this diagnosis. The diagnosis of overlap syndrome between SLE and Gougerot-Sjögren syndrome was established only six years later when the patient developed ocular and oral sicca syndrome with enlargement of the parotid glands.
Blanche
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P
Département de Médecine Interne, Hôpital Cochin, Paris.
Sicard
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D
D000328:Adult; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000009:adverse effects / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000209:etiology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy / Q000209:etiology; D009395:Nephritis, Interstitial / Q000209:etiology*; D012859:Sjogren's Syndrome / Q000150:complications*
D006886:Hydroxychloroquine
Lupus, syndrome sec et néphrite interstitielle chronique. A propos d'une observation.