title: Environmental risk factors for nasopharyngeal carcinoma: a case-control study in northeastern Thailand.
abstract: A case-control study of nasopharyngeal carcinoma was conducted in northeast Thailand, a region which shows an intermediate risk for this neoplasm. The study was conducted to investigate the importance of environmental exposures, particularly salted fish consumption, cigarette smoking, alcohol drinking, and occupational exposure to smoke or dust, as risk factors for the disease. Data from 120 nasopharyngeal cancer cases and the same number of hospital-matched controls indicated that consumption of sea-salted fish at least once a week was a significant risk factor (odds ratio, 2.5; 95% confidence interval, 1.2-5.2). Agricultural workers were also at significantly higher risk (odds ratio, 2.8; 95% confidence interval, 1.3-6.2), and working in agriculture or as a woodcutter was associated with an even higher risk (odds ratio, 8.0; 95% confidence interval, 2.3-28.2). There was no association between nasopharyngeal carcinoma and alcohol drinking or cigarette smoking.
authors.affiliation: Cancer Unit, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Sriamporn
authors.forename: V
authors.initials: V
authors.lastname: Vatanasapt
authors.forename: P
authors.initials: P
authors.lastname: Pisani
authors.forename: S
authors.initials: S
authors.lastname: Yongchaiyudha
authors.forename: V
authors.initials: V
authors.lastname: Rungpitarangsri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004032:Diet / Q000009:adverse effects; D004781:Environmental Exposure; D005260:Female; D005399:Fishes; D005520:Food Preservatives / Q000009:adverse effects; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D016555:Matched-Pair Analysis; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D009790:Occupations; D011159:Population Surveillance; D012042:Registries; D012307:Risk Factors; D013785:Thailand / Q000453:epidemiology
chemical_list: D005520:Food Preservatives