Spectrofluorimetric determination of sulphonamides in pharmaceutical compounds and foods.
Spectrofluorimetry and room temperature photochemically-induced fluorescence (RTPF) have been applied to the determination of sulphacetamide (SAC), sulphaguanidine (SG) and sulphamethazine (SMT) in milk and pharmaceutical formulations. The methods are suitable for determining 0.02-0.10 micrograms ml of SAC, 0.10-0.50 micrograms ml of SG, and 0.40-1.00 micrograms of SMT.
Sanchez Pena
M
M
Department of Analytical Chemistry, Faculty of Sciences, University of Extremadura, Badajoz, Spain.
Salinas
F
F
Mahedero
M C
MC
Aaron
J J
JJ
D000818:Animals; D002626:Chemistry, Pharmaceutical / Q000379:methods; D002851:Chromatography, High Pressure Liquid; D004350:Drug Residues / Q000032:analysis*; D008892:Milk / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013409:Sulfacetamide / Q000032:analysis; D013414:Sulfaguanidine / Q000032:analysis; D013418:Sulfamethazine / Q000032:analysis; D013449:Sulfonamides / Q000032:analysis*
D013449:Sulfonamides; D013414:Sulfaguanidine; D013418:Sulfamethazine; D013409:Sulfacetamide