Hypoxemia in thalassemia.
Data are reviewed describing hypoxemia, a newly identified feature in thalassemia. Evidence indicates platelet aggregation in the pulmonary circulation as being a key factor leading to hypoxemia and cor-pulmonale with right heart failure.
Fucharoen
S
S
Thalassemia Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Winichagoon
P
P
Siritanaratkul
N
N
Sonakul
D
D
Chantaraksri
U
U
Bunyaratvej
A
A
Piankijagum
A
A
Wasi
P
P
D001241:Aspirin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D001784:Blood Gas Analysis; D004176:Dipyridamole / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D005500:Follow-Up Studies; D006333:Heart Failure / Q000209:etiology; D006801:Humans; D000860:Hypoxia / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D010974:Platelet Aggregation; D011652:Pulmonary Circulation; D011660:Pulmonary Heart Disease / Q000209:etiology; D013156:Splenectomy; D013789:Thalassemia / Q000150:complications* / Q000601:surgery
D004176:Dipyridamole; D001241:Aspirin