title: Oxidation of cystathionamine and lanthionamine by lentil seedlings amine oxidase.
abstract: Cystathionamine and lanthionamine are good substrates for lentil seedlings amine oxidase. One mole of hydrogen peroxide and one mole of ammonia per mole of substrate are produced, indicating that only one amino group is oxidized to aldehyde. The aminoaldehydes so originated undergo cyclization by intramolecular Schiff base formation. The pH optimum for the oxidation of either cystathionamine or lanthionamine is 7.0 in potassium phosphate buffer. The Km values are 0.61 and 0.84 mM respectively, similar to that for cystamine (0.8 mM).
authors.affiliation: Istituto di Chimica Biologica, Università di Cagliari.
authors.forename: G
authors.initials: G
authors.lastname: Floris
authors.forename: E
authors.initials: E
authors.lastname: Sanjust
authors.forename: A
authors.initials: A
authors.lastname: Padiglia
authors.forename: C
authors.initials: C
authors.lastname: De Marco
mesh_terms: D000447:Aldehydes / Q000378:metabolism; D006631:Amine Oxidase (Copper-Containing) / Q000378:metabolism*; D000641:Ammonia / Q000378:metabolism; D003540:Cystathionine / Q000031:analogs & derivatives* / Q000378:metabolism; D005021:Ethylamines / Q000378:metabolism*; D007887:Fabaceae / Q000201:enzymology*; D006861:Hydrogen Peroxide / Q000378:metabolism; D007700:Kinetics; D010084:Oxidation-Reduction; D010100:Oxygen / Q000378:metabolism; D010946:Plants, Medicinal; D013057:Spectrum Analysis; D013440:Sulfides / Q000378:metabolism*
chemical_list: D000447:Aldehydes; D005021:Ethylamines; D013440:Sulfides; D003540:Cystathionine; C079767:cystathionamine; D000641:Ammonia; C079766:lanthionamine; D006861:Hydrogen Peroxide; D006631:Amine Oxidase (Copper-Containing); D010100:Oxygen