title: [Effect of experimental hyper- and hypoinsulinemia on the level of cholesterol lipoproteins in aging rats].
abstract: A study was made of the effect of hyper- and hypoinsulinemia on blood serum lipoproteins of 5-6-month and 24-26 month old rats. Total cholesterol levels, cholesterol fraction concentration in lipoproteins, the level of insulinemia, and age showed correlation. Administration of insulin had a positive effect on the serum lipid spectrum, increasing the HDL-C content in aged animals. In alloxan diabetes, VLDL-C concentration in serum was on the increase. Alterations were more pronounced in young rats.
authors.forename: G G
authors.initials: GG
authors.lastname: Gatsko
authors.forename: V V
authors.initials: VV
authors.lastname: Gul'ko
mesh_terms: D000375:Aging / Q000097:blood*; D000818:Animals; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D003921:Diabetes Mellitus, Experimental / Q000097:blood*; D006946:Hyperinsulinism / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D051381:Rats; D017208:Rats, Wistar
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D008074:Lipoproteins; D002784:Cholesterol
vernacular_title: Vliianie éksperimental'noĭ giper- i gipoinsulinemii na uroven' kholesterina lipoproteidov pri starenii u krys.