Growth promoting effect of zinc supplementation in infants of high-risk pregnancies.
This study was made to determine whether zinc deficiency is one of the factors involved in growth retardation of infants of high-risk pregnancies. The high risk factors were hypertension of pregnancy, diabetes mellitus, congenital heart disease, chronic nephritis, rheumatic heart disease and hyperthyroidism. 102 neonatal infants were divided into 3 groups: breast fed group, 37 cases; test group, 32 cases formula-fed with supplementary zinc 1.14-2.28 mg/kg/d; and control group, 33 cases formula-fed and supplemented with Vitamin B complex as placebo. The groups were divided by double-blind and randomized method. There were no differences in the 3 groups in sex ratio, growth status and serum zinc concentration at the beginning of the study. Anthropometric data were obtained at 0, 3 and 6 months.
Hong
Z Y
ZY
Child Health Department, Xinhua Hospital, Shanghai Second Medical University.
Zhang
Y W
YW
Xu
J D
JD
Zhou
J D
JD
Gao
X L
XL
Liu
X G
XG
Shi
Y Y
YY
D004311:Double-Blind Method; D005260:Female; D005526:Food, Formulated; D006130:Growth Disorders / Q000517:prevention & control*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications; D015032:Zinc / Q000008:administration & dosage*
D015032:Zinc