Effect of isoproterenol on 85Sr accumulation in the myocardium of the rat during postnatal ontogeny.
The aim of this study was to establish whether administration of toxic doses of isoproterenol (IPRO) increases the accumulation of strontium--a homologue element of calcium--in the rat heart during postnatal development. It has been shown that in 14-day-old animals 85Sr uptake was not increased; starting from the 30th day of postnatal life this parameter increases significantly up to adulthood.
Ostádalová
I
I
Institute of Physiology, Czechoslovak Academy of Sciences, Prague.
Ostádal
B
B
D000818:Animals; D002118:Calcium / Q000032:analysis / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D006321:Heart / Q000254:growth & development*; D007545:Isoproterenol / Q000494:pharmacology*; D008297:Male; D009206:Myocardium / Q000737:chemistry / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D013326:Strontium Radioisotopes / Q000032:analysis / Q000378:metabolism*
D013326:Strontium Radioisotopes; D007545:Isoproterenol; D002118:Calcium