[The possibilities of using immunological indices as criteria for determining the stage of HIV infection and the disease prognosis].
The authors studied the immune status of 14 HIV-infected patients, 6 of whom had lymphadenopathy, 4 were diagnosed as having AIDS-related complex and 4, a full-blown AIDS. Analysis of laboratory findings showed that of predictive value are serum levels of immunoglobulin B, a CD4 cell count less than 200, reduced populations of CD20 and CD16 lymphocytes, and a depressed response to pokeweed mitogen. Based on the clinical manifestations and laboratory results, three stages characterizing the immune system in HIV infection have been identified.
Chernousov
A D
AD
Eremina
O F
OF
Simonova
A V
AV
Kulakov
V V
VV
Borisova
A M
AM
Pinegin
B V
BV
D000386:AIDS-Related Complex / Q000145:classification / Q000276:immunology; D000163:Acquired Immunodeficiency Syndrome / Q000145:classification / Q000276:immunology; D015703:Antigens, CD / Q000097:blood; D001402:B-Lymphocytes / Q000276:immunology; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D005260:Female; D015658:HIV Infections / Q000145:classification* / Q000276:immunology*; D015497:HIV-1; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D007958:Leukocyte Count; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D011379:Prognosis; D013601:T-Lymphocytes / Q000276:immunology
D015703:Antigens, CD; D007136:Immunoglobulins
Vozmozhnosti ispol'zovaniia immunologicheskikh pokazateleĭ v kachestve kriteriev opredeleniia stadii VICh-infektsii i prognoza zabolevaniia.