title: Spectroscopic studies of the interaction of synthetic RNAs with quinacrine and its analogs.
abstract: The interaction of synthetic RNAs with quinacrine (QAC) and its analogs has been studied by absorption, fluorescence and circular dichroism (CD) measurements. The results indicate that the 2-methoxy group of the acridine ring plays an important role in the appearance of the new absorption band upon binding of QAC to poly-(rA).poly(rU).
authors.affiliation: Department of Chemistry, Faculty of Science, Yamaguchi University, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Nakamura
authors.forename: S
authors.initials: S
authors.lastname: Yoshimatsu
authors.forename: K
authors.initials: K
authors.lastname: Murakami
authors.forename: Y
authors.initials: Y
authors.lastname: Kubota
mesh_terms: D015394:Molecular Structure; D011063:Poly A-U / Q000737:chemistry; D011070:Poly I-C / Q000737:chemistry; D011796:Quinacrine / Q000031:analogs & derivatives / Q000737:chemistry*; D012313:RNA / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D011063:Poly A-U; D012313:RNA; D011796:Quinacrine; D011070:Poly I-C