Distribution of circulating beta-carotene in human plasma lipoproteins.
We examined the distribution of beta-carotene in plasma lipoprotein fractions. In healthy children and adults, LDL contained more beta-carotene than did HDL, but in cord blood more beta-carotene was found in HDL than in LDL. After the oral administration of beta-carotene, its plasma level rose although its distribution in the individual lipoprotein fractions did not change. Among disease conditions associated with hyperlipidemia, the ratio of beta-carotene to plasma lipids was highest in anorexia nervosa, while nephrotic syndrome and diabetes mellitus had similar ratios to each other.
Manago
M
M
Department of Pediatrics, Osaka Medical College, Japan.
Tamai
H
H
Ogihara
T
T
Mino
M
M
D000293:Adolescent; D000328:Adult; D002338:Carotenoids / Q000032:analysis / Q000097:blood* / Q000493:pharmacokinetics; D002648:Child; D002675:Child, Preschool; D002851:Chromatography, High Pressure Liquid; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood; D007223:Infant; D008074:Lipoproteins / Q000097:blood* / Q000737:chemistry; D008297:Male; D011247:Pregnancy; D019207:beta Carotene
D008074:Lipoproteins; D019207:beta Carotene; D002338:Carotenoids