title: [Tumor necrosis factor-alpha and interleukin-1beta in the blood plasma of patients with HIV infection].
abstract: The paper presents examination findings of 67 HIV-infected patients: 32 children aged 2.5 to 16 years and 35 adults aged 21 to 46 years. The proportion of patients with higher alpha-tumor necrosis factor and interleukin-1 beta increased with progression of the disease, the two parameters being higher in the children than in the adults. A correlation was found between the appearance of cytokines in the plasma and some clinical signs, such as fever, weight loss, anemia, neurological disorders. A parallel study of the patients' immunograms indicated significant correlations between the degree of impairments in the composition of lymphocyte subpopulations and the appearance of plasma cytokines.
authors.forename: S A
authors.initials: SA
authors.lastname: Ketlinskiĭ
authors.forename: N M
authors.initials: NM
authors.lastname: Kalinina
authors.forename: S N
authors.initials: SN
authors.lastname: Tsvetkova
authors.forename: A G
authors.initials: AG
authors.lastname: Rakhmanova
authors.forename: V N
authors.initials: VN
authors.lastname: Maslov
authors.forename: N A
authors.initials: NA
authors.lastname: Khaldeeva
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000097:blood* / Q000175:diagnosis / Q000276:immunology; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007375:Interleukin-1 / Q000032:analysis*; D053583:Interleukin-1beta; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D010446:Peptide Fragments / Q000032:analysis*; D012720:Severity of Illness Index; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis*
chemical_list: D007375:Interleukin-1; D053583:Interleukin-1beta; D010446:Peptide Fragments; D014409:Tumor Necrosis Factor-alpha; C052994:interleukin-1beta (163-171)
vernacular_title: Faktor nekroza opukholi-alpha i interleĭkin-1beta v plazme krovi bol'nykh VICh-infektsieĭ.