title: [Invasive nasosinusal aspergillosis in an immunocompetent patient].
abstract: The authors describe a case of invasive nasosinusal aspergillosis in an immunocompetent patient. After a careful bibliographic review, they emphasize that in the present case the diagnosis was made by means of fungal culture as the clinical picture, imaging techniques and histopathological findings were aspecific. The pathogenetic agent resulted Aspergillus tamarii which belongs to the Aspergillus flavus group and is one of the most unusual agents in literature. The treatment of choice, in the invasive form, is surgery that should be as radical as possible followed by a medical therapy. In the present case, after two-phase radical surgery on all the paranasal sinuses, medical treatment with traconazole was employed with excellent local results at a follow-up of one year.
authors.affiliation: Istituto di Clinica Otorinolaringoiatrica, Università Cattolica del Sacro Cuore, Policlinico Universitario A. Gemelli, Roma.
authors.forename: G
authors.initials: G
authors.lastname: Paludetti
authors.forename: M
authors.initials: M
authors.lastname: Rosignoli
authors.forename: E
authors.initials: E
authors.lastname: Ferri
authors.forename: M R
authors.initials: MR
authors.lastname: Cesari
authors.forename: G
authors.initials: G
authors.lastname: Morace
authors.forename: M
authors.initials: M
authors.lastname: Fantoni
authors.forename: J
authors.initials: J
authors.lastname: Galli
mesh_terms: D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis* / Q000382:microbiology / Q000601:surgery; D001231:Aspergillus flavus / Q000302:isolation & purification; D002908:Chronic Disease; D005260:Female; D006801:Humans; D009668:Nose Diseases / Q000175:diagnosis* / Q000382:microbiology / Q000601:surgery; D010254:Paranasal Sinus Diseases / Q000175:diagnosis* / Q000382:microbiology / Q000601:surgery
vernacular_title: Aspergillosi nasosinusale invasiva in paziente immunocompetente.