[The transport of sodium, water and active osmotic substances in different parts of the nephron of patients with chronic glomerulonephritis and hypertension].
The lithium test was conducted to evaluate transport of water, sodium and osmotic active substances in 46 chronic glomerulonephritis (CG) patients. Sixteen CG patients entered group 1. All of them had secondary hypertension (SH). Twelve CG patients with SH symptoms of moderate reduction of endogenic creatinine clearance were assigned to group 2. Twelve patients of group 3 had CG and isolated urinary syndrome. Group 4 consisted of 6 patients with essential hypertension. As shown by the test, association of SH and CG is not an essential factor for renal transport of sodium, water and electrolytes. Some shifts in the transport in group 2 are attributed to reduced number of functioning nephrons. The tendency to enhanced lithium clearance was registered in group 4. This may reflect an increased supply of sodium, water and osmotic active substances to the uriniferous tubules.
Gadaev
A
A
Kaiukov
I G
IG
Ivakhniuk
I S
IS
Nikogosian
Iu A
IuA
D000328:Adult; D001693:Biological Transport, Active; D002908:Chronic Disease; D003404:Creatinine / Q000097:blood; D005921:Glomerulonephritis / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000378:metabolism*; D016651:Lithium Carbonate; D009399:Nephrons / Q000378:metabolism*; D009995:Osmosis; D012964:Sodium / Q000378:metabolism*; D013997:Time Factors; D014867:Water / Q000378:metabolism*
D014867:Water; D016651:Lithium Carbonate; D012964:Sodium; D003404:Creatinine
Transport natriia, vody i osmoticheskikh aktivnykh veshchestv v razlichnykh uchastkakh nefrona u bol'nykh khronicheskim glomerulonefritom i gipertonicheskoĭ bolezn'iu.