[Correlation between urinary excretion of neopterin and levels of thyroid gland hormones in patients with goiter].
The authors assessed in 18 patients with goitre the urinary excretion of neopterin and the blood level of thyroid hormones. They revealed a significant correlation between urinary neopterin excretion and the thyroxine (T4) and triiodothyronine (T3) blood level. This correlation did not apply in female patients treated with large doses of Carbimazol: these patients had a high neopterin excretion, while the thyroid hormone levels were only slightly elevated. This suggests again that Carbimazol has in addition to an antithyroid effect also an immunomodulating action.
Límanová
Z
Z
Laborator pro endokrinologii a metabolismus pri III, interní klinice 1. LF Univerzity Karlovy, Praha.
Tomsová
Z
Z
Schreiber
V
V
D001708:Biopterins / Q000031:analogs & derivatives* / Q000652:urine; D005260:Female; D006042:Goiter / Q000097:blood / Q000188:drug therapy / Q000652:urine*; D006801:Humans; D019798:Neopterin; D013963:Thyroid Hormones / Q000097:blood*
D013963:Thyroid Hormones; D001708:Biopterins; D019798:Neopterin
Korelace mezi mocovou exkrecí neopterinu a hladinou hormonů stítné zlázy u nemocných se strumou.