[The influence of disulfiram on the metabolism of ethanol].
The author discusses the metabolism of disulfiram and the enzymes which metabolize ethanol. The restraining of the activity of ALDH in the liver by disulfiram causes an accumulation of acetaldehyde which in their turn cause a series of psychophysical symptoms which are unpleasant and in some instances dangerous for the patient. Thus, it is important to monitor changes in the activity of ALDH after administration of disulfiram.
Skrzydlewska
E
E
Zakładu Analizy Instrumentalnej AM, Białymstoku.
D000426:Alcohol Dehydrogenase / Q000378:metabolism; D000437:Alcoholism / Q000517:prevention & control; D004221:Disulfiram / Q000494:pharmacology*; D000431:Ethanol / Q000378:metabolism* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008099:Liver / Q000378:metabolism; D008297:Male; D008930:Mitochondria, Liver / Q000201:enzymology
D000431:Ethanol; D000426:Alcohol Dehydrogenase; D004221:Disulfiram
Wpływ disulfiramu na metabolizm etanolu.