title: [Double liver-kidney transplantation in the presence of a positive T cross-match].
abstract: Kidney transplantation, when performed across a positive T lymphocyte cross-match, is always followed by the occurrence of a hyperacute rejection. On the other hand, successful hepatic allografts have been reported under these same conditions. Furthermore, clinically and experimentally hepatic allograft has been reported to induce tolerance of other organs from the same donor. Thus, combined liver-kidney transplantation constitutes an ideal application of these immunological events. We report here the case of a sequential liver-kidney transplantation in which liver transplantation performed prior to kidney transplantation with an organ from the same donor induced kidney tolerance despite an initial positive T lymphocyte cross-match.
authors.affiliation: Hôpital Henri-Mondor, Créteil.
authors.forename: D
authors.initials: D
authors.lastname: Duvoux
authors.forename: D
authors.initials: D
authors.lastname: Cherqui
authors.forename: K
authors.initials: K
authors.lastname: Schultz
authors.forename: P
authors.initials: P
authors.lastname: Bierling
authors.forename: C C
authors.initials: CC
authors.lastname: Abbou
authors.forename: B
authors.initials: B
authors.lastname: Bourgeon
authors.forename: J M
authors.initials: JM
authors.lastname: Métreau
authors.forename: J Y
authors.initials: JY
authors.lastname: Lauzet
authors.forename: S
authors.initials: S
authors.lastname: Terré
authors.forename: D
authors.initials: D
authors.lastname: Dhumeaux
mesh_terms: D000328:Adult; D005923:Glomerulosclerosis, Focal Segmental / Q000601:surgery*; D006650:Histocompatibility Testing / Q000379:methods*; D006801:Humans; D016030:Kidney Transplantation / Q000379:methods*; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology*
vernacular_title: Double transplantation hépatique et rénale en présence d'un cross-match T positif.