CT-guided stereotactic injection of radionuclide for treatment of brain tumors.
The authors report on 40 brain tumor patients treated with CT-guided stereotactic injection of 198Au and 32P. Among the 40 cases were astrocytoma in 23 cases, craniopharyngioma in 9, meningioma in 4, pituitary adenoma in 2, and pinealoma and metastatic carcinoma each in 1 case. The tumors were all located in deep or important areas of the brain which were difficult to deal with by conventional operation. 62 injections of colloidal isotopes were performed, and all were successful. No major adverse effects or complications occurred on follow-up of 6-12 months, 28 patients were improved in their clinical symptoms, and CT scanning showed that the tumor sizes were diminished. The effective rate is 70%.
Tian
Z M
ZM
Department of Neurosurgery, Yan Jing Medical Institute, Beijing, People's Republic of China.
Liu
Z H
ZH
Kang
G Q
GQ
Zhang
Y
Y
Li
S Y
SY
Chen
X H
XH
Chui
Y
Y
Feng
H
H
D000236:Adenoma / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery; D000328:Adult; D001254:Astrocytoma / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000556:secondary / Q000601:surgery*; D003397:Craniopharyngioma / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006050:Gold Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery; D008579:Meningioma / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery; D010761:Phosphorus Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*; D010871:Pinealoma / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery; D016634:Radiosurgery / Q000379:methods*; D013238:Stereotaxic Techniques; D014057:Tomography, X-Ray Computed
D006050:Gold Radioisotopes; D010761:Phosphorus Radioisotopes