title: Pseudophakic endophthalmitis.
abstract: We performed a retrospective study on 45 patients admitted to the Rotterdam Eye Hospital and the Ophthalmic Department of the Academic Medical Center in Amsterdam with pseudophakic endophthalmitis. Vitreous loss during cataract extraction was associated with a significantly increased risk of postoperative endophthalmitis when compared with uncomplicated cataract extraction (p < 0.0001). The incidence of pseudophakic endophthalmitis in diabetic patients was not significantly higher as compared to non-diabetic patients. Vitrectomy in the treatment of postoperative endophthalmitis did not improve the final visual acuity, probably because of selection bias. Methicillin and cephazolin, used intravitreally against gram-positive organisms, failed to provide a good coverage for endophthalmitis due to Staphylococcus epidermidis.
authors.affiliation: Department of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: G V
authors.initials: GV
authors.lastname: Jager
authors.forename: C J
authors.initials: CJ
authors.lastname: Brinkman
authors.forename: C J
authors.initials: CJ
authors.lastname: van Tilburg
authors.forename: W H
authors.initials: WH
authors.lastname: Beekhuis
authors.forename: M V
authors.initials: MV
authors.lastname: Joosse
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002387:Cataract Extraction / Q000009:adverse effects*; D009877:Endophthalmitis / Q000188:drug therapy / Q000209:etiology*; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D014821:Vitrectomy
chemical_list: D000900:Anti-Bacterial Agents