title: Prolonged partial remission of malignant fibrous histiocytoma in posterior mediastinum by immunotherapy.
abstract: The case of a 16-year-old female patient with the giant cell type of malignant fibrous histiocytoma (MFH) in the left posterior mediastinum is reported. This is a very unusual site for MFH. Immunotherapy induced a prolonged partial remission lasting 15 months with a marked reduction in tumor size. The usefulness of immunotherapy for MFH needs to be evaluated.
authors.affiliation: Second Department of Internal Medicine, Ehime University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Muneta
authors.forename: N
authors.initials: N
authors.lastname: Kohno
authors.forename: H
authors.initials: H
authors.lastname: Matsuoka
authors.forename: K
authors.initials: K
authors.lastname: Hiwada
authors.forename: N
authors.initials: N
authors.lastname: Ueda
mesh_terms: D000293:Adolescent; D003131:Combined Modality Therapy; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000276:immunology / Q000473:pathology / Q000628:therapy*; D006801:Humans; D007167:Immunotherapy; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000008:administration & dosage; D008479:Mediastinal Neoplasms / Q000276:immunology / Q000473:pathology / Q000628:therapy*; D010844:Picibanil / Q000008:administration & dosage; D011994:Recombinant Proteins; D012074:Remission Induction
chemical_list: D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D010844:Picibanil