Synthesis of 23 K acute-phase protein by HBV genome carrying PLC/PRF/5 human hepatoma cells.
Elevated synthesis of 23 K protein by human hepatoma PLC/PRF/5 cells was observed after their treatment with conditioned medium from concanavalin A stimulated peripheral-blood monocytes. Increased amount of this protein was first determined 4 hr after the treatment and its maximal level was reached 48 hr later. The role of the 23 K protein remains so far unknown.
Hájnická
V
V
Institute of Preventive and Clinical Medicine, Bratislava, Czechoslovakia.
Fuchsberger
N
N
Stancek
D
D
Volná
A
A
Cervenáková
L
L
D000209:Acute-Phase Proteins / Q000096:biosynthesis*; D006528:Carcinoma, Hepatocellular / Q000378:metabolism* / Q000382:microbiology / Q000473:pathology; D003208:Concanavalin A / Q000494:pharmacology; D017077:Culture Media, Conditioned / Q000494:pharmacology; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects*; D006515:Hepatitis B virus / Q000302:isolation & purification*; D006801:Humans; D008113:Liver Neoplasms / Q000378:metabolism* / Q000382:microbiology / Q000473:pathology; D008213:Lymphocyte Activation; D008222:Lymphokines / Q000378:metabolism / Q000494:pharmacology*; D009363:Neoplasm Proteins / Q000096:biosynthesis*; D013601:T-Lymphocytes / Q000187:drug effects / Q000378:metabolism; D014407:Tumor Cells, Cultured / Q000187:drug effects
D000209:Acute-Phase Proteins; D017077:Culture Media, Conditioned; D008222:Lymphokines; D009363:Neoplasm Proteins; D003208:Concanavalin A