Bone histomorphometry in Cushing's syndrome.
Bone involvement is a common finding in Cushing's syndrome. The actions of corticosteroids on bone have been studied quite intensively but only a few studies of bone histomorphometry in this syndrome have been published. In this paper we present histomorphometric measurements of bone activity in 7 patients with a postoperative reevaluation in two. The results show irregular alterations on histomorphometric parameters with an increased bone resorption and decreased bone formation rate. After surgery the abnormalities changed towards normal.
Borelli
A
A
Endocrine Service, 1st Medical Clinics Hospital das Clínicas, University of São Paulo, Brazil.
Leite
M O
MO
Correa
P H
PH
Jorgetti
V
V
Marcondes
J A
JA
Batalha
J R
JR
Cintra
A B
AB
Wajchenberg
B L
BL
D000328:Adult; D001862:Bone Resorption / Q000473:pathology; D001842:Bone and Bones / Q000473:pathology*; D002118:Calcium / Q000652:urine; D003480:Cushing Syndrome / Q000097:blood / Q000473:pathology* / Q000601:surgery; D005260:Female; D006728:Hormones / Q000097:blood / Q000652:urine; D006801:Humans; D007085:Ilium / Q000473:pathology
D006728:Hormones; D002118:Calcium