title: Clinical efficacy of a low abrasive dentifrice for the relief of cervical dentinal hypersensitivity.
abstract: 2 strontium chloride hexahydrate-containing dentifrices (SCH), similar except for their respective abrasive systems, were compared in a 2-month randomised double-blind parallel clinical study to evaluate their comparative effectiveness in terms of cervical dentinal hypersensitivity. 2 groups of 20 subjects, each with cervical dentinal hypersensitivity, were evaluated for tactile sensitivity by Yeaple probe, air sensitivity using a dental air syringe and subjective perception of pain by means of a visual analogue scale. There was no difference between the dentifrices as regards reduction of cervical dentinal hypersensitivity at each time point. The response to both dentifrices was evident within 4 weeks of use and the degree of improvement increased throughout the 8-week study period. The results support the conclusion that changing the abrasive component of SCH dentifrices did not significantly increase or decrease the (desensitizing) activity of the original product.
authors.affiliation: Department of Periodontology, University of London, UK.
authors.forename: D G
authors.initials: DG
authors.lastname: Gillam
authors.forename: H N
authors.initials: HN
authors.lastname: Newman
authors.forename: E H
authors.initials: EH
authors.lastname: Davies
authors.forename: J S
authors.initials: JS
authors.lastname: Bulman
mesh_terms: D000328:Adult; D000388:Air; D003080:Cold Temperature; D003802:Dentifrices / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000175:diagnosis / Q000517:prevention & control*; D004311:Double-Blind Method; D005260:Female; D005889:Gingival Recession / Q000517:prevention & control; D006801:Humans; D008297:Male; D010147:Pain Measurement; D010812:Physical Stimulation; D012822:Silicon Dioxide / Q000627:therapeutic use; D013324:Strontium / Q000627:therapeutic use*; D014072:Tooth Abrasion / Q000517:prevention & control; D014077:Tooth Erosion / Q000517:prevention & control; D014110:Touch
chemical_list: D003802:Dentifrices; D012822:Silicon Dioxide; C025700:strontium chloride; D013324:Strontium