title: Management of antiphospholipid antibody positivity and elective orthopedic procedures.
abstract: Current management of primary or secondary antiphospholipid antibody (aPL) syndromes with known embolic phenomena requiring anticoagulation is empiric in the setting of elective orthopedic procedures. Short-term withdrawal of warfarin with continuance of aspirin and glucocorticoid therapy was undertaken for sequential bilateral knee replacements in a lupus patient with aPL. Her course was successfully managed without thrombo-embolic complications.
authors.affiliation: Division of Rheumatology and Immunology, Oklahoma Memorial Hospital, Oklahoma City.
authors.forename: W M
authors.initials: WM
authors.lastname: Schnitz
authors.forename: K A
authors.initials: KA
authors.lastname: Lister
authors.forename: G A
authors.initials: GA
authors.lastname: McCarty
mesh_terms: D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000097:blood*; D000925:Anticoagulants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000188:drug therapy / Q000276:immunology; D005260:Female; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000276:immunology* / Q000601:surgery*; D010020:Osteonecrosis / Q000150:complications / Q000276:immunology / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control; D013923:Thromboembolism / Q000517:prevention & control
chemical_list: D017152:Antibodies, Antiphospholipid; D000925:Anticoagulants