title: Optic neuritis in children with poor recovery of vision.
abstract: We reviewed the records of 10 children with optic neuritis in whom recovery of vision was poor or incomplete. Our cases were otherwise similar to those described in previous studies in that they were always bilateral, often accompanied by a viral prodrome (seven of 10), and usually associated with disc oedema (seven of 10). Seven of twenty eyes had a final visual acuity of 6/60 or worse and only one patient regained 6/6 vision in either eye. In three patients the best vision in either eye was 6/60 or worse. Recovery of vision was often slow, taking up to six years. Five of 10 patients have developed multiple sclerosis (MS), and one child had acute disseminated encephalomyelitis (ADEM) with optic neuritis. Optic neuritis in children does not always carry a good prognosis for recovery of vision; however, the failure of vision recovery in a short period of time does not necessarily indicate a poor outcome. Some children with optic neuritis develop MS, which can develop even when optic neuritis follows a viral illness.
authors.affiliation: Department of Ophthalmology, University of California Medical Center, San Francisco 94143.
authors.forename: W V
authors.initials: WV
authors.lastname: Good
authors.forename: R
authors.initials: R
authors.lastname: Muci-Mendoza
authors.forename: B O
authors.initials: BO
authors.lastname: Berg
authors.forename: D R
authors.initials: DR
authors.lastname: Frederick
authors.forename: C S
authors.initials: CS
authors.lastname: Hoyt
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004679:Encephalomyelitis / Q000503:physiopathology; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000503:physiopathology; D009902:Optic Neuritis / Q000150:complications / Q000503:physiopathology*; D010211:Papilledema / Q000473:pathology; D011379:Prognosis; D014786:Vision Disorders / Q000209:etiology / Q000503:physiopathology*; D014792:Visual Acuity