title: Anti-müllerian hormone and Sertoli cell function.
abstract: Anti-müllerian hormone (AMH) is a glycoprotein that is produced by immature Sertoli cells and is responsible for the regression of müllerian ducts in male fetuses. It is a useful marker of testicular function in children, when anorchia is suspected and in intersex states. In the persistent müllerian duct syndrome, both AMH-positive and AMH-negative forms have been reported. In three cases of the latter, a mutation of the AMH gene is thought to have been responsible for the condition.
authors.affiliation: Unité de Recherches sur l'Endocrinologie du Développement (INSERM), Montrouge, France.
authors.forename: N
authors.initials: N
authors.lastname: Josso
mesh_terms: D000818:Animals; D054304:Anti-Mullerian Hormone; D002675:Child, Preschool; D012734:Disorders of Sex Development / Q000503:physiopathology; D004700:Endocrine System Diseases / Q000503:physiopathology; D006023:Glycoproteins; D006131:Growth Inhibitors / Q000235:genetics / Q000502:physiology*; D006801:Humans; D007223:Infant; D008297:Male; D009095:Mullerian Ducts / Q000502:physiology; D012708:Sertoli Cells / Q000502:physiology*; D013735:Testicular Hormones / Q000235:genetics / Q000502:physiology*
chemical_list: D006023:Glycoproteins; D006131:Growth Inhibitors; D013735:Testicular Hormones; D054304:Anti-Mullerian Hormone