[Immunologic reaction differences of non-histone chromosome proteins (NHCP) in myometrium and leiomyoma of the uterus in women].
Immune sera against non-histone chromosomal proteins (NHCP) of myometrium and leiomyoma were raised in our laboratory in rabbits after injection with purified antigens. (NHCP) were extracted 0.35M NaCl from 6 myometrium and leiomyoma tissue samples. Sera contained precipitating and non-precipitating antibodies reacting in Ouchterlony and ELISA tests with homologous and heterologous antigens. Serum against leiomyoma NHCP reacted higher extinction values with myometrium than with homological antigens. NHCP tissue concentration (mg/g) was higher for myometrium in spite NHCP/DNA ratio bigger for leiomyoma. Above mentioned results indicate antigenicity alterations of leiomyoma tissue when compared to normal myometrium of woman uterus.
Miturski
R
R
II Kliniki Ginekologii Operacyjnej Akademii Medycznej, Lublinie.
D000328:Adult; D002868:Chromosomal Proteins, Non-Histone / Q000276:immunology*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000276:immunology*; D009215:Myometrium / Q000276:immunology*; D012016:Reference Values; D014594:Uterine Neoplasms / Q000276:immunology*
D002868:Chromosomal Proteins, Non-Histone
Róznice reakcji immunologicznych białek niehistonowych chromatyny jadrowej (NHCP) mieśniówki i mieśniaka macicy u kobiet.