[Research on myasthenia gravis in children with HLA supratype].
38 cases of MG Children's patients were typed for HLA-I, II and III antigens. It shows that MG significantly associated with HLA-A2, Bw46 and DRw9. Their relative risk were 3.60, 8.18. 4.60, Pc < 0.05 or 0.001 respectively. The association with C4 and Bf were not found. Aw19 is seemed as a protection factor of this disease. These results are similar with the research on Chinese MG patients in Hong Kong but are quite different with those of caucasian data.
Zhang
X G
XG
HLA Laboratory, Beijing Pediatrics Institute.
D044466:Asian People; D002648:Child; D002675:Child, Preschool; D002681:China; D005260:Female; D015234:HLA-A Antigens / Q000097:blood; D015789:HLA-A2 Antigen / Q000097:blood; D015235:HLA-B Antigens / Q000097:blood*; D006684:HLA-DR Antigens / Q000097:blood; D059810:HLA-DR Serological Subtypes; D006801:Humans; D007223:Infant; D008297:Male; D009157:Myasthenia Gravis / Q000276:immunology*
D015234:HLA-A Antigens; C043205:HLA-A19 antigen; D015789:HLA-A2 Antigen; D015235:HLA-B Antigens; C080311:HLA-B46 antigen; D006684:HLA-DR Antigens; D059810:HLA-DR Serological Subtypes; C038988:HLA-DR9 antigen