[The mechanisms of the porphyrin conformation of normal blood hemoglobin and in pathology].
The spectra of resonance Raman scattering of blood in norm and under pathology (myocardial infarction and sepsis), as well after artificial hemotransfusion or UV photomodification have been studied. It has been shown that under heart pathology the structure of hemoglobin porphyrin macrocycle of erythrocytes changes, the size of porphyrin "nucleus" increases. The opposite conditions are observed at blood sepsis. It has been found that the traditional methods in tissue restoration, hemotransfusion and UV photomodification of blood don't result in complete restoration of hemoporphyrin molecule.
Maksimov
G V
GV
Churin
A A
AA
Sokolova
T N
TN
Pashchenko
V Z
VZ
D001769:Blood / Q000528:radiation effects; D001803:Blood Transfusion; D001804:Blood Transfusion, Autologous; D006343:Heart Septal Defects / Q000097:blood / Q000628:therapy; D006454:Hemoglobins / Q000032:analysis* / Q000528:radiation effects; D006801:Humans; D008968:Molecular Conformation / Q000528:radiation effects; D009203:Myocardial Infarction / Q000097:blood / Q000628:therapy; D011166:Porphyrins / Q000097:blood* / Q000528:radiation effects; D012016:Reference Values; D018805:Sepsis / Q000097:blood / Q000628:therapy; D013059:Spectrum Analysis, Raman; D014467:Ultraviolet Therapy
D006454:Hemoglobins; D011166:Porphyrins
Mekhanizmy konformatsii porfirinov gemoglobina krovi v norme i pri patologii.