title: [Chromosome fragile sites in patients with multiple primary tumors and familial forms of breast cancer].
abstract: An analysis was carried out of chromosomal site-fragility in patients with primary multiple tumors and familial breast cancer. A possible correlation is discussed between fragile sites, breakpoints in chromosome rearrangements in cancer patients and the localization of oncogenes mapped in chromosomal regions involved in said rearrangements.
authors.forename: N P
authors.initials: NP
authors.lastname: Kuleshov
authors.forename: G D
authors.initials: GD
authors.lastname: Cortina-Guerrero
authors.forename: G A
authors.initials: GA
authors.lastname: Razinkova
authors.forename: R F
authors.initials: RF
authors.lastname: Gar'kavtseva
authors.forename: M D
authors.initials: MD
authors.lastname: Nefedov
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Kuzina
authors.forename: V P
authors.initials: VP
authors.lastname: Letiagin
mesh_terms: D001943:Breast Neoplasms / Q000097:blood / Q000235:genetics*; D002478:Cells, Cultured / Q000648:ultrastructure; D002869:Chromosome Aberrations; D043283:Chromosome Fragile Sites; D002873:Chromosome Fragility; D005260:Female; D005819:Genetic Markers; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D009378:Neoplasms, Multiple Primary / Q000097:blood / Q000235:genetics*
chemical_list: D005819:Genetic Markers
vernacular_title: Izuchenie khromosomnoĭ saĭt-lomkosti u bol'ynkh s pervichno-mnozhestvennymi opukholiami i semeĭnymi formami raka molochnoĭ zhelezy.