title: [The early high-dose immunoglobulin treatment of neonatal autoimmune thrombocytopenia].
abstract: The paper reports the case of a neonate suffering from autoimmune neonatal thrombocytopenia whose mother had suffered from previous idiopathic thrombocytopenia purpura. Although asymptomatic, the baby received early treatment with high doses of immunoglobulin G (1 g/kg) in a single dose. Treatment was repeated on day 12 using the same method. No other treatment was associated with IgG. The Authors confirm the good level of tolerability and efficacy of IgG in the treatment of autoimmune neonatal thrombocytopenia without complications.
authors.affiliation: Divisione Pediatria, USSL n. 21, Presidio Ospedaliero-Morbegno, Sondrio.
authors.forename: S
authors.initials: S
authors.lastname: Murgia
authors.forename: E
authors.initials: E
authors.lastname: Del Curto
authors.forename: G
authors.initials: G
authors.lastname: Zecca
mesh_terms: D015551:Autoimmunity; D005314:Embryonic and Fetal Development; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000008:administration & dosage / Q000627:therapeutic use*; D007231:Infant, Newborn; D007275:Injections, Intravenous; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D013921:Thrombocytopenia / Q000188:drug therapy* / Q000276:immunology
chemical_list: D007074:Immunoglobulin G
vernacular_title: Trattamento precoce di trombocitopenia neonatale autoimmune con immunoglobuline ad alto dosaggio.