Alpha-tocopherol: a potent inhibitor of platelet adhesion.
Administration of vitamin E in doses of 400 IU/day exerts a potent inhibition of platelet adhesion as measured in a laminar flow chamber. Adhesion to all surfaces tested was reduced and appeared to be related to a limited pseudopodia formation in alpha-tocopherol-enriched platelets.
Steiner
M
M
Division of Hematology, Brown University, Providence, R.I.
D000328:Adult; D000975:Antioxidants / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010973:Platelet Adhesiveness / Q000187:drug effects*; D015203:Reproducibility of Results; D014810:Vitamin E / Q000494:pharmacology*
D000975:Antioxidants; D014810:Vitamin E