title: Numerous SP-positive pyramidal neurons in cat neocortex are glutamate-positive.
abstract: An immunocytochemical technique that allows visualization of two antigens in the same neuron was used to verify the possibility that some neocortical pyramidal neurons contain both glutamate (Glu) and substance P (SP) immunoreactivity. The results show that a large fraction of SP-positive pyramidal neurons are also Glu-positive, and indicate that in a small population of cortical neurons a fast excitatory synaptic transmitter and a slow peptidic modulator coexist.
authors.affiliation: Institute of Human Physiology, University of Ancona, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Conti
authors.forename: M
authors.initials: M
authors.lastname: Fabri
authors.forename: A
authors.initials: A
authors.lastname: Minelli
mesh_terms: D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000166:cytology*; D005971:Glutamates / Q000032:analysis*; D018698:Glutamic Acid; D007150:Immunohistochemistry; D009474:Neurons / Q000166:cytology*; D011712:Pyramidal Tracts / Q000166:cytology*; D013003:Somatosensory Cortex / Q000166:cytology; D013373:Substance P / Q000032:analysis*
chemical_list: D005971:Glutamates; D013373:Substance P; D018698:Glutamic Acid