Screening for toxoplasmosis in pregnant women: presentation of a screening programme in the former "East"-Germany, and the present status in Germany.
The results of the screening programme (including the examination of fetal IgM) in East-Germany, related to the efficiency of therapy (pyrimethamine/sulfonamid) of the fetal infection risk are presented. For comparison the results of a prospective study of toxoplasmosis in pregnancy (n = 1697) without therapy, and follow up of the connatal infected infants to the age of 9/10 years old are shown. Recommendations for the diagnostic and therapeutical management in Germany for the future are presented.
Hengst
P
P
Department of Obstetrics and Gynecology, Humboldt-University (Charité), Berlin, Germany.
D004359:Drug Therapy, Combination; D005260:Female; D005858:Germany; D005859:Germany, East; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008403:Mass Screening / Q000379:methods*; D009313:National Health Programs; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis* / Q000188:drug therapy; D011739:Pyrimethamine / Q000627:therapeutic use; D013449:Sulfonamides / Q000627:therapeutic use; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000188:drug therapy; D014125:Toxoplasmosis, Congenital / Q000517:prevention & control*
D013449:Sulfonamides; D011739:Pyrimethamine