title: Effect of oral curcumin administration on serum peroxides and cholesterol levels in human volunteers.
abstract: The effect of curcumin administration in reducing the serum levels of cholesterol and lipid peroxides was studied in ten healthy human volunteers, receiving 500 mg of curcumin per day for 7 days. A significant decrease in the level of serum lipid peroxides (33%), increase in HDL Cholesterol (29%), and a decrease in total serum cholesterol (11.63%) were noted. As curcumin reduced serum lipid peroxides and serum cholesterol, the study of curcumin as a chemopreventive substance against arterial diseases is suggested.
authors.affiliation: Amala Cancer Research Centre, Amala Nagar, Trichur.
authors.forename: K B
authors.initials: KB
authors.lastname: Soni
authors.forename: R
authors.initials: R
authors.lastname: Kuttan
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001835:Body Weight / Q000187:drug effects; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D003474:Curcumin / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008054:Lipid Peroxides; D014280:Triglycerides; D002784:Cholesterol; D003474:Curcumin