[Extramedullary blast transformation in chronic granulocytic leukemia].
A patient with Ph1(Philadelphia chromosome) positive chronic granulocytic leukemia and extramedullary blast transformation (crisis) in lymph nodes of neck and axillae which appeared after 4-year of treatment with busulfan is presented. Biopsy of lymph node and histopathological examination showed lymphoblastic infiltration. The patient was treated with radiotherapy and chemotherapy with protocol COP. He survived 7 months and expired due to renal insufficiency.
Vidović
A
A
Institute of Haematology, University Clinical Centre, Belgrade.
Janković
G
G
Suvajdzić
N
N
Colović
M
M
D001752:Blast Crisis; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010677:Philadelphia Chromosome
Ekstramedulski blastni preobrazaj u hronicnoj granulocitnoj leukemiji.