[Elastin and arteriosclerosis: determination and characterization of elastin peptides in blood].
During pathologies such as arteriosclerosis and emphysema, degradation of elastin by elastases occurs and elastin peptides are produced. In order to evaluate elastin degradation, measurements of elastin peptide concentration in human blood were carried out. According to elastin peptides used for obtention of antibodies and for ELISA, the measured values are different. Elastin peptides have several biological effects: they are chemotactic, modify ion fluxes and several intracellular mechanisms.
Jacob
M P
MP
Laboratoire de Biologie du Tissu Conjonctif, UA CNRS 1460, Faculté de Médecine, Créteil.
Wei
S M
SM
Ghuysen-Itard
A
A
Fülöp
T
T
Robert
L
L
D001161:Arteriosclerosis / Q000097:blood*; D004549:Elastin / Q000097:blood* / Q000502:physiology; D006801:Humans; D010455:Peptides / Q000097:blood* / Q000502:physiology
D010455:Peptides; D004549:Elastin
Elastine et artériosclérose: dosage et caractérisation des peptides d'élastine du sang.