title: [Electrophysiological effects of intravenous propafenone for treating atrial-ventricular nodal dual pathways reentrant tachycardia].
abstract: The acute electrophysiological effects of intravenous propafenone were studied through programmed electrical stimulation in 9 patients with atrio-ventricular nodal dual pathways reentrant tachycardia (AVNDP-RT). The results showed that propafenone prolonged significantly the effective refractory period of atrial ventricular nodal fast pathway (AVN-FP) in retrograde conduction and might further terminate the paroxysmal supraventricular tachycardia (PSVT). It is an effective drug for treating AVNDP-RT. Neither blood pressure dropping nor other side effects were observed.
authors.affiliation: Department of Medicine, Rui Jin Hospital, Shanghai.
authors.forename: L
authors.initials: L
authors.lastname: Shi
authors.forename: J A
authors.initials: JA
authors.lastname: Qian
authors.forename: W H
authors.initials: WH
authors.lastname: Qi
mesh_terms: D000328:Adult; D000368:Aged; D004594:Electrophysiology; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D011405:Propafenone / Q000008:administration & dosage / Q000627:therapeutic use*; D012032:Refractory Period, Electrophysiological; D013611:Tachycardia, Atrioventricular Nodal Reentry / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D011405:Propafenone