5-Lipoxygenase inhibitors isolated from the mushroom Boletopsis leucomelas (Pers.) Fayod.
Terphenyl compounds, tentatively named Bl-I (1), Bl-II (2), Bl-III (3), Bl-IV (4) and Bl-V (5), showing 5-lipoxygenase inhibitory activity have been isolated from the mushroom Boletopsis leucomelas (Pers.) Fayod. On the basis of physico-chemical and spectral evidence, they were concluded to be a series of cycloleucomelone-leucoacetates.
Takahashi
A
A
Faculty of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
Kudo
R
R
Kusano
G
G
Nozoe
S
S
D000818:Animals; D001487:Basidiomycota / Q000737:chemistry*; D006168:Guinea Pigs; D016859:Lipoxygenase Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D009504:Neutrophils / Q000187:drug effects / Q000201:enzymology
D016859:Lipoxygenase Inhibitors