Effects of sodium iodate on the electroretinogram c-wave in the cat.
The c-wave of the vitreal electroretinogram decreased in amplitude and was replaced by a slow, polarity reversed potential following an i.v. infusion of sodium iodate, as first described by Noell. Intraretinal recordings showed that the negative-going c-wave, induced by iodate (30 mg/kg), was composed of reduced slow pIII and trans-epithelial c-wave. The effects of iodate on these components may originate from direct effects on the retinal pigment epithelial cells, namely, a large decrease in the trans-epithelial resistance. Other factors could have contributed to the change in the c-wave amplitude.
Kiryu
J
J
Department of Ophthalmology, Kyoto University, Faculty of Medicine, Japan.
Yamamoto
F
F
Honda
Y
Y
D000818:Animals; D002415:Cats; D003623:Dark Adaptation; D004596:Electroretinography / Q000187:drug effects; D007452:Iodates / Q000494:pharmacology*; D008027:Light; D010857:Pigment Epithelium of Eye / Q000502:physiology; D011188:Potassium / Q000502:physiology; D012160:Retina / Q000502:physiology*; D013997:Time Factors
D007452:Iodates; D011188:Potassium; C032285:sodium iodate