[The role of noradrenaline in regulating myocardial oxidative metabolism in rats with different resistances to hypoxia].
The effects of noradrenaline infusion on the regulation of oxidative metabolism in isolated rat heart were studied. It appeared that functional and metabolic parameters of heart of non-resistant and high-resistant to hypoxia rats were different. Noradrenaline changed the balance between aerobic and anaerobic processes in rat heart. It is evident that heart adrenoreceptors are involved in regulation of oxidative metabolism responsible for individual resistance of rat heart to hypoxia.
Luk'ianova
L D
LD
Kurlaev
S N
SN
D000818:Animals; D004305:Dose-Response Relationship, Drug; D006321:Heart / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D000860:Hypoxia / Q000503:physiopathology*; D007113:Immunity, Innate / Q000187:drug effects / Q000502:physiology; D066298:In Vitro Techniques; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D009638:Norepinephrine / Q000494:pharmacology / Q000502:physiology*; D010101:Oxygen Consumption / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects / Q000502:physiology
D011941:Receptors, Adrenergic; D009638:Norepinephrine
O roli noradrenalina v reguliatsii okislitel'nogo metabolizma miokarda krys s raznoĭ rezistentnost'iu k gipoksii.