Long-term follow-up of acute partial transverse myelopathy.
We carried out a prospective, long-term, combined clinical and MRI follow-up study on 15 patients hospitalized at the Montreal Neurological Institute between 1985 and 1988 with a diagnosis of acute partial transverse myelopathy of unknown etiology. Twelve of the 15 (80%) developed clinically definite or lab-supported definite multiple sclerosis (MS) by the end of a mean follow-up period of 38.5 months. The presence of CNS periventricular white matter lesions by cranial MRI at onset increased the likelihood of development of MS to 93%.
Ford
B
B
Department of Neurology, McGill University Faculty of Medicine, Montreal, PQ, Canada.
Tampieri
D
D
Francis
G
G
D000208:Acute Disease; D000328:Adult; D001921:Brain / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000209:etiology* / Q000503:physiopathology; D009135:Muscular Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D009460:Neurologic Examination; D011446:Prospective Studies; D013997:Time Factors