[Application of multistate model to the analysis of relationship between cumulative occupational exposure and occurrence of disease].
The relationship between cumulative exposure and response used to be estimated by using the two state life table method. But since the occurrence of the response is related to the time factor after exiting exposure, this method may not provide correct description of this relationship. Based on multiple state model, this paper put forward a new method which modifies the effect of the time after exiting exposure on this relationship. The data from a cohort of 1113 underground male workers in a tin mine was taken as an example to illustrate the merit of this method.
Yi
Q L
QL
Shanghai Medical University.
D006801:Humans; D015993:Life Tables; D008175:Lung Neoplasms / Q000453:epidemiology*; D008297:Male; D008906:Mining; D015233:Models, Statistical; D016273:Occupational Exposure; D011336:Probability; D014001:Tin
D014001:Tin