title: [Fonsecaea pedrosoi-caused chromoblastomycosis in the state of Maranhão. I. The clinical, epidemiological and evolutionary aspects].
abstract: The aim of this study was to observe the clinical and of epidemiological behavior of chromoblastomycosis in the State of Maranhão. A retrospective and prospective study of 13 cases was performed at the infectious diseases section of the Hospital dos Servidores do Estado do Maranhão, from November, 1988 to July, 1991. In the investigation a protocol record was used with a view to further analysis. A higher prevalence between 50 and 60 years of age (46.1%) and in male patients (92.3%) was noted. Twelve patients (92.3%) were from Maranhão State, and 10 of them (76.9%) came from the western microregion of the State of Maranhão. Regarding occupation, 92.3% were land workers, and most of them presented the lesions on the lower limbs (84.6%) of a vegetant warty aspect, brown in color with itching. Histopathological examination diagnosed chromomycosis in 100% of the cases. Culture was performed in 11 cases, and Fonsecaea pedrosoi isolated in 9 of them. Treatment with 5-fluorocytosine resulted in a good evolutive response. This study indicates the existence of a probable endemic area of chromomycosis in hinterland of Maranhão (western microregion) that hither to unknown.
authors.affiliation: Departamento de Patologia, Universidade Federal do Maranhão, Hospital dos Servidores do Estado do Maranhão, São Luís.
authors.forename: A C
authors.initials: AC
authors.lastname: Mello e Silva
authors.forename: A
authors.initials: A
authors.lastname: Serra Neto
authors.forename: C E
authors.initials: CE
authors.lastname: Galvão
authors.forename: S G
authors.initials: SG
authors.lastname: Marques
authors.forename: A C
authors.initials: AC
authors.lastname: Saldanha
authors.forename: C M
authors.initials: CM
authors.lastname: Pedroso e Silva
authors.forename: O
authors.initials: O
authors.lastname: Fischman
authors.forename: R R
authors.initials: RR
authors.lastname: da Silva
authors.forename: M do R
authors.initials: Mdo R
authors.lastname: Costa
authors.forename: J M
authors.initials: JM
authors.lastname: Costa
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001706:Biopsy; D001938:Brazil / Q000453:epidemiology; D002862:Chromoblastomycosis / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D003904:Mitosporic Fungi / Q000302:isolation & purification; D015995:Prevalence; D011446:Prospective Studies; D012189:Retrospective Studies; D012737:Sex Factors; D012867:Skin / Q000382:microbiology / Q000473:pathology
vernacular_title: Cromoblastomicose produzida por Fonsecaea pedrosoi no Estado do Maranhão. I--Aspectos clínicos, epidemiologicos e evolutivos.