title: [Vaccination against hepatitis B at the Palma-Palmilla Health Center of Málaga].
abstract: OBJECTIVE
  To describe the results of a programme of anti-hepatitis B vaccination of high-risk groups.
  
  
  METHODS
  Observational descriptive study, of a retrospective character. SITE. At a community level within the confines of Primary Care in the Palma-Palmilla (Málaga) Health Centre, between June 1989 and March 1990.
  
  
  METHODS
  Individuals with a high risk of Hepatitis B infection, according to a modified CDC (Centre for Diseases Control) scale. The subjects were found during their attendance as patients and from among the Health Centre staff.
  
  
  METHODS
  The second generation vaccine developed by genetic engineering (Engerix B) was used. It was administered by intramuscular injection in a dosage of 20 mcg to those weighing more than 25 kilos; and of 10 mcg to those weighing less than 25 kilos. The vaccination pattern was of three doses in months 0, 1 and 6, followed by a monthly sero-conversion check.
  
  
  RESULTS
  169 individuals began the vaccination programme: 17.7% were health workers and 81.6% lived with carriers of the virus. 87.6% completed the vaccination programme. Sero-conversion in the individuals controlled was 95.5%. Only five patients were sero-negative after the third vaccination. Of these four cases achieved sero-conversion after a fourth or fifth dosage.
  
  
  CONCLUSIONS
  We found there was a high rate of sero-conversion; and also high acceptance of the programme by those living with a carrier.
authors.affiliation: Centro de Salud Palma-Palmilla, Unidad Docente de Medicina Familiar y Comunitaria, Málaga.
authors.forename: F
authors.initials: F
authors.lastname: Extremera
authors.forename: A
authors.initials: A
authors.lastname: Hernández
authors.forename: B
authors.initials: B
authors.lastname: Macías
authors.forename: M A
authors.initials: MA
authors.lastname: Tarilonte
authors.forename: P
authors.initials: P
authors.lastname: Badía
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D003151:Community Health Centers / Q000706:statistics & numerical data; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000097:blood; D017325:Hepatitis B Vaccines / Q000008:administration & dosage / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D012737:Sex Factors; D013030:Spain / Q000453:epidemiology
chemical_list: D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines
vernacular_title: Vacunación contra la hepatitis B en el Centro de Salud Palma-Palmilla de Málaga.