title: Relationship of serum antihistone antibody level to the patient's age.
abstract: The serum antihistone antibody (AHA) positivity of patients with various autoimmune diseases was compared with their positive reaction for antinuclear factor, rheumatoid factor, lupus erythematosus factor, cryoglobulin, immunocomplex, C-reactive protein, total protein, gamma globulin, IgG and IgM. In non-drug-induced SLE cases the predictive value of the AHA test was not higher than that of the other tests. It was striking that in 42% of patients with non-autoimmune disease aged over 70 the AHA test was positive. Elevated IgM values were recorded in about 70% of positive AHA samples.
authors.affiliation: Department of Clinical Chemistry, University Medical School, Pécs, Hungary.
authors.forename: A
authors.initials: A
authors.lastname: Lakatos
authors.forename: J
authors.initials: J
authors.lastname: Sétáló
authors.forename: K
authors.initials: K
authors.lastname: Jobst
authors.forename: A
authors.initials: A
authors.lastname: Pár
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001323:Autoantibodies / Q000097:blood*; D001327:Autoimmune Diseases / Q000097:blood / Q000276:immunology*; D001798:Blood Proteins / Q000032:analysis; D002648:Child; D006657:Histones / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood / Q000145:classification; D007074:Immunoglobulin G / Q000097:blood / Q000145:classification; D007075:Immunoglobulin M / Q000097:blood / Q000145:classification; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000276:immunology; D009103:Multiple Sclerosis / Q000097:blood / Q000276:immunology; D012871:Skin Diseases / Q000097:blood / Q000276:immunology
chemical_list: D001323:Autoantibodies; D001798:Blood Proteins; D006657:Histones; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M