title: Evaluation of provocation tests in tonsillogenic focal infection from the standpoint of fibrinolytic activity.
abstract: In this paper, we carried out provocation tests by means of ultra-short wave stimulation in patients with focal infection including palmoplantar pustulosis and examined the changes in fibrinolytic activity of the circulating blood. In the positive group with palmoplantar pustulosis, the t-PA level was slightly increased after the provocation and the FDP level in the positive group was increased. On the other hand, the AT-III activity in the positive group with palmoplantar pustulosis was decreased and the antiplasmin activity in the positive group was increased. The changes of antiplasmin activity observed in this experiment did not correspond with the pathophysiological explanation of an increased fibrinolytic activity in the circulating blood. It was suggested that a positive provocation test is accompanied by an increase in fibrinolytic activity in the circulating blood of patients with focal infection of the tonsil, and the increase in fibrinolytic activity is closely related to the positiveness of the provocation test.
authors.affiliation: Department of Otorhinolaryngology, School of Medicine, University of the Ryukyus, Okinawa, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ura
authors.forename: K
authors.initials: K
authors.lastname: Nakahodo
authors.forename: M
authors.initials: M
authors.lastname: Nakamura
authors.forename: T
authors.initials: T
authors.lastname: Kosugi
mesh_terms: D000911:Antibodies, Monoclonal; D000933:Antifibrinolytic Agents / Q000032:analysis / Q000097:blood; D001775:Blood Circulation; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D005341:Fibrinolysin / Q000032:analysis*; D005490:Focal Infection / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007239:Infections; D008297:Male; D010960:Plasminogen Activators / Q000096:biosynthesis; D011565:Psoriasis / Q000097:blood* / Q000150:complications; D014069:Tonsillitis / Q000097:blood / Q000175:diagnosis* / Q000209:etiology
chemical_list: D000911:Antibodies, Monoclonal; D000933:Antifibrinolytic Agents; D005340:Fibrinogen; D010960:Plasminogen Activators; D005341:Fibrinolysin