title: A rare case of extramedullary plasmacytoma in the mediastinum.
abstract: A rare case of extramedullary plasmacytoma in the mediastinum is reported. An 80-year-old man was admitted for further examination of a mediastinal tumor. Chest computed tomography (CT) revealed a large mediastinal mass and right interlobar pleural effusion. Needle biopsy under CT guidance established a diagnosis of plasmacytoma. Immunohistochemical staining revealed that the tumor cells were producing monoclonal IgA kappa. Serum immunoelectrophoresis revealed an IgA kappa monoclonal component with a serum concentration of 5,040 mg/ml. The bone marrow aspiration was normal. Bone roentgenogram and bone scintigram showed osteoporosis but no neoplastic lesion.
authors.affiliation: Department of Internal Medicine, Isahaya Insurance General Hospital, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Miyazaki
authors.forename: S
authors.initials: S
authors.lastname: Kohno
authors.forename: A
authors.initials: A
authors.lastname: Sakamoto
authors.forename: K
authors.initials: K
authors.lastname: Komori
authors.forename: I
authors.initials: I
authors.lastname: Sasagawa
authors.forename: S
authors.initials: S
authors.lastname: Futagawa
authors.forename: K
authors.initials: K
authors.lastname: Hara
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism; D007145:Immunoglobulin kappa-Chains / Q000378:metabolism; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000276:immunology; D010265:Paraproteinemias / Q000175:diagnosis / Q000276:immunology; D010954:Plasmacytoma / Q000175:diagnosis* / Q000276:immunology; D016066:Pleural Effusion, Malignant / Q000175:diagnosis; D014057:Tomography, X-Ray Computed
chemical_list: D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains