title: Distribution of circulating beta-carotene in human plasma lipoproteins.
abstract: We examined the distribution of beta-carotene in plasma lipoprotein fractions. In healthy children and adults, LDL contained more beta-carotene than did HDL, but in cord blood more beta-carotene was found in HDL than in LDL. After the oral administration of beta-carotene, its plasma level rose although its distribution in the individual lipoprotein fractions did not change. Among disease conditions associated with hyperlipidemia, the ratio of beta-carotene to plasma lipids was highest in anorexia nervosa, while nephrotic syndrome and diabetes mellitus had similar ratios to each other.
authors.affiliation: Department of Pediatrics, Osaka Medical College, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Manago
authors.forename: H
authors.initials: H
authors.lastname: Tamai
authors.forename: T
authors.initials: T
authors.lastname: Ogihara
authors.forename: M
authors.initials: M
authors.lastname: Mino
mesh_terms: D000293:Adolescent; D000328:Adult; D002338:Carotenoids / Q000032:analysis / Q000097:blood* / Q000493:pharmacokinetics; D002648:Child; D002675:Child, Preschool; D002851:Chromatography, High Pressure Liquid; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood; D007223:Infant; D008074:Lipoproteins / Q000097:blood* / Q000737:chemistry; D008297:Male; D011247:Pregnancy; D019207:beta Carotene
chemical_list: D008074:Lipoproteins; D019207:beta Carotene; D002338:Carotenoids