Cerebrospinal fluid flow. II. Physiology of respiration-related pulsations.
Cerebrospinal fluid (CSF) flow in the cerebral aqueduct and spinal canal was analysed using real-time magnetic resonance imaging measurement techniques. Respiration-induced rhythmic modulation of the cardiac-related oscillating CSF pulsation in the cerebral aqueduct and spinal canal was found. Deep inspiration was immediately followed by a marked increase in downward CSF flow in the cervical spinal canal, whereas a delay of about two heart beats was seen before downward flow from the third to the fourth ventricle increased. This pattern was also detected during yawning and was followed by a marked increase of blood flow in the internal jugular vein.
Schroth
G
G
Department of Neuroradiology, University of Tübingen, Federal Republic of Germany.
Klose
U
U
D002535:Cerebral Aqueduct / Q000033:anatomy & histology; D002552:Cerebral Ventricles / Q000033:anatomy & histology; D002555:Cerebrospinal Fluid / Q000502:physiology*; D004562:Electrocardiography; D005583:Fourier Analysis; D006801:Humans; D007089:Image Enhancement; D001239:Inhalation / Q000502:physiology; D008279:Magnetic Resonance Imaging / Q000379:methods; D009200:Myocardial Contraction / Q000502:physiology; D011673:Pulsatile Flow; D012119:Respiration / Q000502:physiology*; D012212:Rheology; D013115:Spinal Canal / Q000033:anatomy & histology; D013346:Subarachnoid Space / Q000033:anatomy & histology