title: Effect of some food preservatives on aflatoxin production.
abstract: The effect of some food preservatives, such as sorbic (SA) and propionic (PA) acids, on aflatoxin production in synthetic media or in moistened (20%) wheat seeds, was investigated. The preservatives tested, added to synthetic media at sublethal concentrations both at the inoculum and after 5 days of incubation, stimulated aflatoxin production by Aspergillus parasiticus. Sorbic and propionic acids are metabolized by the fungus in vivo and in vitro. Lower concentrations of PA and SA (0.05 to 0.1% w/w) in wheat seeds are ineffective against both fungal growth and aflatoxin production, whilst the combined use of butylated hydroxy toluene (BHT), and PA or SA was more effective in controlling aflatoxin production than their use as single components.
authors.affiliation: Istituto Nazionale della Nutrizione, Rome, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Panfili
authors.forename: A A
authors.initials: AA
authors.lastname: Fabbri
authors.forename: C
authors.initials: C
authors.lastname: Fanelli
authors.forename: E
authors.initials: E
authors.lastname: Quattrucci
mesh_terms: D000348:Aflatoxins / Q000096:biosynthesis*; D001230:Aspergillus / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D002084:Butylated Hydroxytoluene / Q000008:administration & dosage / Q000494:pharmacology; D005520:Food Preservatives / Q000494:pharmacology*; D007700:Kinetics; D011422:Propionates / Q000008:administration & dosage / Q000494:pharmacology; D013011:Sorbic Acid / Q000008:administration & dosage / Q000494:pharmacology; D014908:Triticum / Q000382:microbiology
chemical_list: D000348:Aflatoxins; D005520:Food Preservatives; D011422:Propionates; D002084:Butylated Hydroxytoluene; C029658:propionic acid; D013011:Sorbic Acid