[The effect of chemical damage to the adrenal cortex on its ontogenetic development].
We studied adrenal gland of rats at the age of 1 month, which underwent injections of dioxin-preparations during a week. In 1, 6, 12 days; 1, 3, 5, 5, 7, 13 months adrenal gland mass, adrenal cortex size, adrenocorticocytes number, 3B-ol-steroid dehydrogenase and succinate dehydrogenase activities of the experimental animals differed greatly from that of the control. It was found that chemical damage of the gland at an early stage changes it greatly during the following ontogenic development.
Ryzhavskiĭ
B Ia
BIa
Ivashkov
E A
EA
D000302:Adrenal Cortex / Q000187:drug effects* / Q000201:enzymology / Q000254:growth & development; D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology; D008297:Male; D009097:Multienzyme Complexes / Q000187:drug effects; D009929:Organ Size / Q000187:drug effects; D011375:Progesterone Reductase / Q000187:drug effects; D011810:Quinoxalines / Q000494:pharmacology; D051381:Rats; D013251:Steroid Isomerases / Q000187:drug effects; D013385:Succinate Dehydrogenase / Q000187:drug effects; D013997:Time Factors
C021425:3 beta-hydroxysteroid oxidoreductase-delta(5) 3-ketosteroid isomerase; D000890:Anti-Infective Agents; D009097:Multienzyme Complexes; D011810:Quinoxalines; C001077:dioxidine; D011375:Progesterone Reductase; D013385:Succinate Dehydrogenase; D013251:Steroid Isomerases
Vliianie khimicheskogo povrezhdeniia korkovogo veshchestva nadpochechnika na ego ontogeneticheskoe razvitie.