A new cyclopyrophosphate as a bacterial antistressor?
In a number of bacteria an unusual glycosyl pyrophosphate (31P NMR signal chemical shift at about -15 ppm) was detected when the cells were subjected to oxidative stress. This substance from Brevibacterium ammoniagenes has now been identified as 2-methyl-butan-1,2,3,4,-tetraol-2,4-cyclopyrophosphate, which is accumulated in the cell under certain conditions in concentrations of of about 50 mM. It is now suggested that this compound is the long sought after bacterial antistressor.
Ostrovsky
D
D
Bakh Institute of Biochemistry, USSR Academy of Sciences, Moscow.
Shipanova
I
I
Sibeldina
L
L
Shashkov
A
A
Kharatian
E
E
Malyarova
I
I
Tantsyrev
G
G
D001951:Brevibacterium / Q000737:chemistry*; D011756:Diphosphates / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D004896:Erythritol / Q000031:analogs & derivatives*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010084:Oxidation-Reduction
D011756:Diphosphates; C073443:2-methyl-butan-1,2,3,4-tetraol-2,4-cyclopyrophosphate; D004896:Erythritol