title: [The hemostatic effect of vagotomy in acute gastroduodenal ulcers complicated by massive hemorrhage].
abstract: The clinico-experimental investigation has shown high efficiency of the bilateral subdiaphragmatic truncal vagotomy in treatment of patients with acute gastroduodenal ulcers complicated by massive hemorrhage. The haemostatic effect of the operation is related to the inhibited acid gastric secretion, proteolytic activity of the intragastric content as well as to the activation of serotonin-containing cells and increased tonus of the sympathetic nervous system, which is responsible for gastric vessel spasm, shortens time of bleeding, increases the amount of thrombocytes and their aggregation. When vagotomy with interventions draining the stomach is not possible, suturing (dissection) of bleeding acute ulcers is recommended in combination with prolonged novocain blockade of vagus nerves.
authors.forename: A A
authors.initials: AA
authors.lastname: Kurygin
authors.forename: I V
authors.initials: IV
authors.lastname: Gaĭvoronskiĭ
authors.forename: O N
authors.initials: ON
authors.lastname: Skriabin
authors.forename: N N
authors.initials: NN
authors.lastname: Lebedev
authors.forename: L P
authors.initials: LP
authors.lastname: Tikhonova
authors.forename: V M
authors.initials: VM
authors.lastname: Sidorov
authors.forename: I S
authors.initials: IS
authors.lastname: Osipov
authors.forename: A A
authors.initials: AA
authors.lastname: Ivashchenko
authors.forename: S V
authors.initials: SV
authors.lastname: Chepur
authors.forename: A V
authors.initials: AV
authors.lastname: Filippov
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D004285:Dogs; D005260:Female; D005743:Gastrectomy; D006488:Hemostasis, Surgical / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D009407:Nerve Block / Q000379:methods; D010437:Peptic Ulcer / Q000150:complications* / Q000401:mortality / Q000601:surgery; D010438:Peptic Ulcer Hemorrhage / Q000401:mortality / Q000601:surgery*; D011343:Procaine; D013536:Suture Techniques; D014628:Vagotomy / Q000379:methods; D014630:Vagus Nerve
chemical_list: D011343:Procaine
vernacular_title: Gemostaticheskiĭ éffekt vagotomii pri ostrykh gastroduodenal'nykh iazvakh, oslozhnennykh massivnym krovotecheniem.