title: In vitro evaluation of NaF and APF-gel application on surface microhardness of enamel in children of low, optimum and high fluoride areas.
abstract: An in vitro study was conducted on 78 sound human pre-molars collected from low (0.24 ppmF), optimum (0.7 ppmF) and known endemic fluoride areas (> 1.5 ppmF), to study the effects of topical application of sodium fluoride and APF-gel on surface microhardness of enamel of these three areas using Vickers microhardness measurements before and after application of topical fluorides at time intervals of 1/2 an hour, 6 hours and 24 hours. It was found that both the topical fluorides increased the surface microhardness of enamel in the three areas; the maximum increase in surface microhardness was observed in fluorosed teeth. APF-gel was found to be more effective than sodium fluoride.
authors.affiliation: Bapuji Dental College and Hospital, Davangere, India.
authors.forename: V V
authors.initials: VV
authors.lastname: Reddy
authors.forename: K R
authors.initials: KR
authors.lastname: Indushekar
mesh_terms: D000149:Acidulated Phosphate Fluoride / Q000494:pharmacology* / Q000627:therapeutic use; D002648:Child; D003743:Dental Enamel / Q000187:drug effects*; D005457:Fluoridation / Q000009:adverse effects; D009050:Fluorosis, Dental / Q000188:drug therapy / Q000209:etiology; D005782:Gels; D006244:Hardness; D006245:Hardness Tests; D006801:Humans; D066298:In Vitro Techniques; D012969:Sodium Fluoride / Q000494:pharmacology* / Q000627:therapeutic use; D013499:Surface Properties; D013997:Time Factors
chemical_list: D005782:Gels; D000149:Acidulated Phosphate Fluoride; D012969:Sodium Fluoride