Determination of sodium cromoglycate in pharmaceutical dosage forms using TLC-densitometry.
A TLC-UV densitometric method for the determination of sodium cromoglycate (SCG) in ophthalmic solutions, gels and capsules has been developed. After TLC separation of active substance on silica gel GF254 using methanol-water-ethylacetate (15:45:40 v/v/v) as the mobile phase, densitometric measurements were performed with HPTLC scanner at 254 nm. The proposed method is rapid and simple, free from interference by adjuvants and can be suggested for the routine analysis of sodium cromoglycate.
Kocić-Pesić
V
V
Association of Pharmacy, Belgrade, Yugoslavia.
Radulovic
D
D
Pećanac
D
D
Zivanović
L
L
D002214:Capsules; D002855:Chromatography, Thin Layer; D004205:Cromolyn Sodium / Q000032:analysis*; D003720:Densitometry; D005782:Gels; D009883:Ophthalmic Solutions; D013056:Spectrophotometry, Ultraviolet
D002214:Capsules; D005782:Gels; D009883:Ophthalmic Solutions; D004205:Cromolyn Sodium