[Behavior of SCC marker level in cervix erosion, cervix dysplasia and cervical pre-invasive carcinoma].
The work presents the results of studies on the behaviour of SCC antigen in 52 patients aged 21-70 years, with pathologic changes involving the uterine cervix and classified to the groups of erosion, dysplasia and carcinoma in different stage of advancement. The SCC antigen was determined in patients blood sera by radioimmunologic method, on the basis of Abbott Firm testes. An increase in concentration was observed exceed the norm (2 ng/ml) in cases of CIN and CIS. The rise of marker depended on the stage of the neoplastic process advancement in the uterine cervix.
Uzar
A
A
Kliniki Ginekologii Operacyjnej Instytutu Połoznictwa i Ginekologii Pomorskiej Akademii Medycznej, Szczecinie.
Rzepka-Górska
I
I
Kosmowska
B
B
D000328:Adult; D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000032:analysis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011230:Precancerous Conditions / Q000175:diagnosis*; D012698:Serologic Tests; D015843:Serpins; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis*; D002579:Uterine Cervical Erosion / Q000175:diagnosis*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D015843:Serpins; C051072:squamous cell carcinoma-related antigen
Zachowanie sie poziomu markera SCC w nadzerkach, stanach przednowotworowych oraz w raku szyjki macicy.