title: [Orbital apex syndrome disclosing naso-oculo-cerebral zygomycosis].
abstract: In a 70-year-old male patient with untreated diabetes a febrile orbital apex syndrome of rapid onset revealed a rhino-orbito-cerebral zygomycosis. Biopsies of the ethmoidal mucosa showed numerous colonies of the Rhizopus genus. Despite medical treatment (amphotericin B) and surgery (ethmoidectomy), the patient died within one week. Rhino-cerebral zygomycosis is a rare disease which occurs in diabetic and immunocompromised patients.
authors.affiliation: Service de Neurologie, Hôpital Pasteur, Nice.
authors.forename: M H
authors.initials: MH
authors.lastname: Mahagne
authors.forename: P
authors.initials: P
authors.lastname: Hofman
authors.forename: P
authors.initials: P
authors.lastname: Bedoucha
authors.forename: M
authors.initials: M
authors.lastname: Lanteri Minet
authors.forename: M
authors.initials: M
authors.lastname: Chatel
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D003929:Diabetic Neuropathies / Q000209:etiology; D005004:Ethmoid Bone / Q000601:surgery; D015521:Ethmoid Sinusitis / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D009091:Mucormycosis / Q000150:complications* / Q000188:drug therapy; D009916:Orbital Diseases / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D013577:Syndrome
chemical_list: D000666:Amphotericin B
vernacular_title: Syndrome de l'apex orbitaire révélateur d'une zygomycose naso-oculo-cérébrale.