The efficacy of clarythromycin (A-56268, TE-031) in the treatment of genital chlamydial infection.
The authors report the preliminary results of an experience of treatment with clarythromycin in Chlamydia trachomatis endocervicitis/endourethritis; 100% of 51 outpatients treated had negative ELISA results 7-10 days after the end of treatment with clarythromycin 500 mg. b.i.d. for 7 days. Among 64 female outpatients with chlamydial cervicitis treated with erythromycin 1 g b.i.d. for 7 days, 88% were negative at ELISA at the same intervals after therapy. The authors conclude that the efficacy of clarythromycin in this experience makes it use worthy of other and more extensive studies.
Calzolari
E
E
Division of Clinical Pathology, S. Anna Institute, University La Sapienza, Rome, Italy.
Ciampaglia
G
G
Steffe
M
M
Vallania
F M
FM
Pavia
C
C
Dattilo
D
D
D000328:Adult; D002690:Chlamydia Infections / Q000188:drug therapy* / Q000382:microbiology; D017291:Clarithromycin / Q000627:therapeutic use*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy* / Q000382:microbiology; D005832:Genital Diseases, Male / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D014526:Urethritis / Q000188:drug therapy / Q000382:microbiology; D002575:Uterine Cervicitis / Q000188:drug therapy / Q000382:microbiology
D017291:Clarithromycin