[Stabilization and function of liposomes].
Liposomes stability can be improved by covering them with polysaccharide derivatives. The anchoring mechanism of these derivatives into the lipid membrane has been studied and explained. In order to improve liposome specificity, protein transfer from erythrocytes and platelets into liposome membrane has been carried out. The effect of a newly developed phospholipid, DDPC, on the efficiency and the selectivity of protein transfer is reported.
Rosilio
V
V
Physico-Chimie des Surfaces et Innovation en Pharmacotechnie, URA CNRS 1218, Faculté de Pharmacie, Université Paris XI.
Sunamoto
J
J
Puisieux
F
F
Albrecht
G
G
Baszkin
A
A
D001792:Blood Platelets / Q000737:chemistry; D001798:Blood Proteins / Q000008:administration & dosage; D004337:Drug Carriers; D004355:Drug Stability; D004912:Erythrocytes / Q000737:chemistry; D066298:In Vitro Techniques; D008081:Liposomes / Q000378:metabolism*; D011134:Polysaccharides / Q000378:metabolism
D001798:Blood Proteins; D004337:Drug Carriers; D008081:Liposomes; D011134:Polysaccharides
Stabilisation et fonctionnalisation des liposomes.