title: [Relationship between the crystal lattice structure and the biological action of some agonists of amino acid receptors].
abstract: The crystal structures of glycine, taurine, GABA, beta-alanine were compared. The quantity and the accuracy of distances coincidence between nitrogen and oxygen atoms were used as a criterion of similarity of the crystalline structures. The conclusion is made about a correlation between crystalline structure of agonists and their effect on amino acid receptors. It is assumed that in case of a cooperative effect of agonist on the receptor a mutual arrangement of molecules on the receptor surface is similar to their arrangement in the agonist crystal.
authors.forename: L S
authors.initials: LS
authors.lastname: Kertser
authors.forename: K V
authors.initials: KV
authors.lastname: Baev
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D003461:Crystallography; D005998:Glycine / Q000737:chemistry; D009584:Nitrogen / Q000737:chemistry; D010100:Oxygen / Q000737:chemistry; D017459:Receptors, Amino Acid; D011956:Receptors, Cell Surface / Q000187:drug effects*; D013654:Taurine / Q000737:chemistry; D015091:beta-Alanine / Q000737:chemistry; D005680:gamma-Aminobutyric Acid / Q000737:chemistry
chemical_list: D000596:Amino Acids; D017459:Receptors, Amino Acid; D011956:Receptors, Cell Surface; D015091:beta-Alanine; D013654:Taurine; D005680:gamma-Aminobutyric Acid; D009584:Nitrogen; D010100:Oxygen; D005998:Glycine
vernacular_title: Sviaz' mezhdu stroeniem kristallicheskoĭ reshetki i biologicheskim deĭstviem nekotorykh agonistov aminokislotnykh retseptorov.