title: Two-dimensional 1H NMR spectroscopy of normal and pathological human plasma: complete water suppression and further assignment of resonances.
abstract: Two-dimensional J-resolved and correlated 1H NMR spectra with complete water suppression have been obtained to further characterize a metabolic pattern for normal and pathological human plasma samples. 1H COSY spectra have been recorded on plasma from 12 patients with cancer in order to check for the possible presence of fucose. Our results show that there is no evidence for the presence of fucosylated lipids in the plasma of these patients.
authors.affiliation: Centre de Résonance Magnétique Biologique et Médicale, URA-CNRS 1186, Faculté de Médecine, Marseille, France.
authors.forename: M
authors.initials: M
authors.lastname: Kriat
authors.forename: S
authors.initials: S
authors.lastname: Confort-Gouny
authors.forename: J
authors.initials: J
authors.lastname: Vion-Dury
authors.forename: P
authors.initials: P
authors.lastname: Viout
authors.forename: P J
authors.initials: PJ
authors.lastname: Cozzone
mesh_terms: D005643:Fucose / Q000032:analysis*; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009369:Neoplasms / Q000097:blood*; D010949:Plasma / Q000737:chemistry*; D011522:Protons; D012016:Reference Values; D014867:Water / Q000737:chemistry*
chemical_list: D011522:Protons; D014867:Water; D005643:Fucose