title: [Peripheral nerves injection injury: the clinical and experimental study].
abstract: The results of operative management of peripheral nerve postinjection injuries in 58 patients are reported. Neurolysis is one effective method in treating nerve postinjection injuries with excellent and good results observed in 64.6 percent of patients in this series. We also investigated the early changes in neurophysiological, histological and ultrastructural studies in the peroneal nerve of the rabbit. The results from early exploration and 0.9% NaCl irrigation were compared with those from late extraneural and intraneural neurolysis. The results showed that the injury occurs early in the nerve following intrafacicular injection and may proceed quickly to a certain degree of severity, so timely operation is advisable early incision of the epineurium with saline irrigation is superior to the neurolysis in treating nerve injuries as proved by the experimental study which suggests that the former can be used as an emergency operation for the management of this type of nerve injuries.
authors.affiliation: Institute of Orthopedics and Traumatology, Fourth Military Medical University.
authors.forename: Q S
authors.initials: QS
authors.lastname: Zhu
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular / Q000009:adverse effects*; D007275:Injections, Intravenous / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000209:etiology / Q000473:pathology / Q000601:surgery; D010543:Peroneal Nerve / Q000293:injuries* / Q000473:pathology / Q000601:surgery*; D011817:Rabbits; D012584:Sciatic Nerve / Q000293:injuries* / Q000601:surgery; D013997:Time Factors