The synthesis of 2-O-alkyl-myo-inositol 1-phosphates as competitive inhibitors of inositol monophosphatase.
Russell
M G
MG
Merck Sharp & Dohme Research Laboratories, Neuroscience Research Centre, Harlow, Essex, United Kingdom.
Baker
R
R
Billington
D C
DC
D000478:Alkylation; D001667:Binding, Competitive / Q000502:physiology; D006868:Hydrolysis; D007295:Inositol Phosphates / Q000138:chemical synthesis* / Q000494:pharmacology; D015394:Molecular Structure; D010744:Phosphoric Monoester Hydrolases / Q000037:antagonists & inhibitors*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D007295:Inositol Phosphates; D010744:Phosphoric Monoester Hydrolases; C021822:myo-inositol-1 (or 4)-monophosphatase