Escherichia coli multiplication and lesions in the respiratory tract of chickens inoculated with infectious bronchitis virus and/or E. coli.
Escherichia coli numbers and histopathological changes were studied in the respiratory tract of line 151 chickens intranasally inoculated with infectious bronchitis virus (IBV) and/or virulent E. coli; this line is highly susceptible to IBV. Chickens inoculated with IBV alone showed increased numbers of E. coli in the trachea and had tracheitis, airsacculitis, and bronchiolitis. One of 17 chickens inoculated with IBV alone died with fibrinopurulent serositis. Chickens inoculated with IBV and E. coli had more severe and persistent respiratory lesions than those inoculated with IBV alone. E. coli was isolated from tracheas of chickens inoculated with IBV and E. coli more frequently than from chickens inoculated with IBV alone. In this group, 14 of 27 chickens died with tracheal plugs or with fibrinopurulent serositis. There was neither increased numbers of E. coli nor significant lesions in the respiratory tract of the group inoculated with E. coli alone. These results suggest that IBV may facilitate E. coli invasion into the lower respiratory tract of the chicken.
Nakamura
K
K
AFRC Institute for Animal Health, Houghton Laboratory, Huntingdon, Cambridgeshire, England.
Cook
J K
JK
Frazier
J A
JA
Narita
M
M
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002645:Chickens / Q000382:microbiology*; D003333:Coronaviridae Infections / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D004926:Escherichia coli / Q000254:growth & development*; D004927:Escherichia coli Infections / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D001351:Infectious bronchitis virus / Q000254:growth & development* / Q000276:immunology; D011201:Poultry Diseases / Q000382:microbiology* / Q000473:pathology; D012140:Respiratory Tract Diseases / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*
D000914:Antibodies, Viral