The ideal anti-thrombotic drug.
An ideal antithrombotic drug should inhibit thrombosis without affecting hemostasis. It should have a long half life. It should be absorbed after oral administration; it should be safe and it should have a wide therapeutic range. These criteria are discussed using new antithrombotics as examples.
Sixma
J J
JJ
Department of Haematology (G03.647), University Hospital Utrecht, The Netherlands.
de Groot
P G
PG
D000284:Administration, Oral; D002561:Cerebrovascular Disorders / Q000517:prevention & control; D015195:Drug Design; D005343:Fibrinolytic Agents / Q000009:adverse effects / Q000493:pharmacokinetics* / Q000494:pharmacology; D006207:Half-Life; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D009203:Myocardial Infarction / Q000517:prevention & control
D005343:Fibrinolytic Agents