title: Cyclic pentapeptide endothelin antagonists with high ETA selectivity. Potency- and solubility-enhancing modifications.
authors.forename: K
authors.initials: K
authors.lastname: Ishikawa
authors.forename: T
authors.initials: T
authors.lastname: Fukami
authors.forename: T
authors.initials: T
authors.lastname: Nagase
authors.forename: K
authors.initials: K
authors.lastname: Fujita
authors.forename: T
authors.initials: T
authors.lastname: Hayama
authors.forename: K
authors.initials: K
authors.lastname: Niiyama
authors.forename: T
authors.initials: T
authors.lastname: Mase
authors.forename: M
authors.initials: M
authors.lastname: Ihara
authors.forename: M
authors.initials: M
authors.lastname: Yano
mesh_terms: D000595:Amino Acid Sequence; D003500:Cyclization; D016232:Endothelins / Q000378:metabolism; D008969:Molecular Sequence Data; D010456:Peptides, Cyclic / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D011487:Protein Conformation; D011956:Receptors, Cell Surface / Q000037:antagonists & inhibitors* / Q000378:metabolism; D017466:Receptors, Endothelin; D013329:Structure-Activity Relationship
chemical_list: D016232:Endothelins; D010456:Peptides, Cyclic; D011956:Receptors, Cell Surface; D017466:Receptors, Endothelin; C072247:cyclo(Trp-Asp-Pro-Val-Leu)