Milky spots reaction to schistosomal mansoni infection.
Milky spots (MS), considered by the authors as a Coelomatic Lympho-myelopoietic Organ (CLMO), present a strong reactivity during experimental schistosomal mansoni infection, characterized by an increase of lymphocytes, macrophages, plasmocytes, mast cells, neutrophils and expression of eosinophil metaplasia. Intraperitoneal injection of purified Schistosoma mansoni (Sm) eggs provoked a rise in the number and size of MS, which developed the sessile marginal and pedunculated types. The authors conclude that egg antigens are, at least partially, responsible for MS reactivity during Sm infection.
Lenzi
H L
HL
Departamento de Patologia, Instituto Oswaldo Cruz, Rio de Janeiro, Brasil.
Oliveira
D N
DN
Borojevic
R
R
Lenzi
J A
JA
D000818:Animals; D002465:Cell Movement; D005260:Female; D007274:Injections, Intraperitoneal; D007962:Leukocytes / Q000473:pathology*; D008221:Lymphoid Tissue / Q000098:blood supply / Q000276:immunology / Q000473:pathology*; D008297:Male; D008322:Mammals; D008643:Mesentery / Q000473:pathology*; D009852:Omentum / Q000473:pathology*; D010063:Ovum / Q000276:immunology; D011817:Rabbits; D012550:Schistosoma mansoni / Q000276:immunology; D012555:Schistosomiasis mansoni / Q000276:immunology / Q000473:pathology*