title: Needle-localized biopsy of occult breast lesions: an update.
abstract: We have performed 207 needle-localized breast biopsies for nonpalpable, mammographically suspicious lesions over the past 6 years. A mass lesion and grouped microcalcifications were associated with malignancy, while a mass with microcalcifications was never associated with malignancy. Biopsy revealed malignancy in 26 cases (12.6%), with 19 of 22 (86.4%) having no histologic evidence of axillary spread. Advanced age and a past history of a breast cancer were again the risk factors present in a significant number of the patients with a positive biopsy result. There were 11 complications (5.3%): three hematomas (1.4%), one infection (0.5%), and seven (3.4%) required a repeat biopsy to remove the suspicious lesion missed on the original biopsy. We conclude that needle-localized breast biopsy continues to be a reliable method of detecting early breast carcinoma. Given the minimal morbidity, this procedure should be done in all patients with mammographically suspicious nonpalpable breast lesions.
authors.affiliation: Department of Surgery, David Grant United States Air Force Medical Center, Travis Air Force Base, CA 94535-5300.
authors.forename: M J
authors.initials: MJ
authors.lastname: Snell
authors.forename: L B
authors.initials: LB
authors.lastname: Ostrow
authors.forename: J J
authors.initials: JJ
authors.lastname: DuBois
authors.forename: L M
authors.initials: LM
authors.lastname: Boyle
authors.forename: L W
authors.initials: LW
authors.lastname: Calfee
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods*; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D002277:Carcinoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D002278:Carcinoma in Situ / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008327:Mammography; D008408:Mastectomy; D008875:Middle Aged; D008889:Military Personnel; D012307:Risk Factors; D014481:United States