Polylactide and polyglycolic acid-reinforced coralline hydroxy-apatite for the reconstruction of cranial bone defects in the rabbit.
The possibility of using coralline hydroxy-apatite in combination with polylactide and polyglcycolic acid instead of a bone graft in the skull region is examinated. Coralline hydroxy-apatite blocks strengthened with a membrane made of a combination of polylactide and polyglycolic acid were inserted into bony defects created in 12 rabbit skulls. The blocks were observed during a follow-up of 12 months. They became fixed to the surrounding bone and no adverse effects or harmful reactions in the nearby tissues could be detected.
Antikainen
T
T
Department of Surgery, Oulu University Central Hospital, Finland.
Ruuskanen
M
M
Taurio
R
R
Kallioinen
M
M
Serlo
W
W
Törmälä
P
P
Waris
T
T
D000818:Animals; D001672:Biocompatible Materials; D017886:Durapatite; D005549:Foreign-Body Reaction / Q000473:pathology; D006882:Hydroxyapatites; D016348:Osseointegration / Q000502:physiology; D011091:Polyesters; D011100:Polyglycolic Acid; D019736:Prostheses and Implants; D011817:Rabbits; D012886:Skull / Q000473:pathology / Q000601:surgery*; D014945:Wound Healing / Q000502:physiology
D001672:Biocompatible Materials; D006882:Hydroxyapatites; D011091:Polyesters; D011100:Polyglycolic Acid; C033616:poly(lactide); D017886:Durapatite