[ACTH-producing small-cell lung carcinoma].
Small-cell lung cancer may be accompanied by hypercortisolism due to secretion of adrenal stimulating peptides. This occurs almost exclusively in case of extensive disease. The neuroendocrine cell, from which these tumours may originate, plays an important part in the production of these peptides. Four patients are described with small-cell lung cancer and clinical presentation of hypercortisolism, particularly manifesting itself with hypokalaemia.
Cramer
M J
MJ
Afd. Inwendige Geneeskunde, St. Antonius Ziekenhuis, Nieuwegein.
Slee
P H
PH
Schramel
F M
FM
Vanderschueren
R G
RG
Wagenaar
S
S
D000308:Adrenocortical Hyperfunction / Q000209:etiology; D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000368:Aged; D018288:Carcinoma, Small Cell / Q000150:complications / Q000378:metabolism*; D006801:Humans; D007008:Hypokalemia / Q000209:etiology; D008175:Lung Neoplasms / Q000150:complications / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011379:Prognosis
D000324:Adrenocorticotropic Hormone
ACTH-producerend kleincellig longcarcinoom.