title: Regulation of intracellular cyclic AMP concentrations in hepatocytes involves the integrated activation and desensitization of adenylyl cyclase coupled with the action and activation of specific isoforms of cyclic AMP phosphodiesterase.
authors.affiliation: Department of Biochemistry, University of Glasgow, U.K.
authors.forename: M D
authors.initials: MD
authors.lastname: Houslay
authors.forename: S L
authors.initials: SL
authors.lastname: Griffiths
authors.forename: Y M
authors.initials: YM
authors.lastname: Horton
authors.forename: C
authors.initials: C
authors.lastname: Livingstone
authors.forename: M
authors.initials: M
authors.lastname: Lobban
authors.forename: F
authors.initials: F
authors.lastname: Macdonald
authors.forename: N
authors.initials: N
authors.lastname: Morris
authors.forename: J
authors.initials: J
authors.lastname: Pryde
authors.forename: G
authors.initials: G
authors.lastname: Scotland
authors.forename: Y
authors.initials: Y
authors.lastname: Shakur
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000378:metabolism*; D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D004789:Enzyme Activation; D006706:Homeostasis; D007527:Isoenzymes / Q000378:metabolism*; D007700:Kinetics; D008099:Liver / Q000378:metabolism*
chemical_list: D007527:Isoenzymes; D000242:Cyclic AMP; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D000262:Adenylyl Cyclases