[The effect of suloctidil and acetylsalicylic acid on eicosanoid synthesis in human platelets].
The study aimed at comparing an effect of suloctidil and acetylsalicylic acid on malonyldialdehyde levels resulting from the arachidonic acid metabolism in blood platelets. It was shown that inhibitory effect of suloctidil is more potent than that of acetylsalicylic acid. Therefore the first is more inhibitor of an enzymatic metabolism of arachidonate in blood platelets than the latter.
Tkaczewski
W
W
III Kliniki Chorób Wewnetrznych IMW.
Buczyński
A
A
Dziedziczak-Buczyńska
M
M
Wachowicz
B
B
Kedziora
J
J
D000328:Adult; D001241:Aspirin / Q000494:pharmacology*; D001792:Blood Platelets / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D008315:Malondialdehyde / Q000097:blood*; D013468:Suloctidil / Q000494:pharmacology*
D008315:Malondialdehyde; D001241:Aspirin; D013468:Suloctidil
Wpływ syloktydylu i kwasu acetylosalicylowego na synteze prostanoidów w krwinkach płytkowych człowieka.