[The effect of 6-hydroxydopamine injections into the nucleus accumbens and substantia nigra on rat behavior].
Bilateral infusion of 6-hydroxydophamine (15 mg/ml) into the n. accumbens and substantia nigra accelerated the avoidance conditioning and increased the dopamine and 3,4-dihydroxiphenylacetic acid levels in the striatum as compared with the rats which had only been injected the same agent in the substantia nigra alone. Infusion of this agent into the n. accumbens can be used to compensate for the nigrostriatal deficit.
Saul'skaia
N B
NB
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects* / Q000502:physiology; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D004298:Dopamine / Q000378:metabolism; D008297:Male; D008845:Microinjections; D009714:Nucleus Accumbens / Q000187:drug effects* / Q000502:physiology; D016627:Oxidopamine / Q000008:administration & dosage* / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology; D013378:Substantia Nigra / Q000187:drug effects* / Q000502:physiology; D013997:Time Factors
D011954:Receptors, Dopamine; D016627:Oxidopamine; D004298:Dopamine
Vliianie vvedeniĭ 6-gidroksidofamina v prilezhashchee iadro i chernuiu substantsiiu na povedenie krys.