[Changes in beta-endorphin receptor on T-lymphocytes in burned patients and their significance].
The changes in beta-endorphin receptor on the peripheral T lymphocytes were assayed in 30 burned patients (average burn area 38.1 +/- 30.0% of TBSA) and 20 healthy volunteers with radioactive ligand I-beta-endorphin. Results showed that the binding sites of beta-endorphin receptor on T lymphocytes were significantly decreased in various degrees, while kd values were increased, in patients major burns. In patients with smaller burns, the above parameters showed no significant difference from the normal. There were also decreased binding sites when complications such as infection occurred.
Xue
J Z
JZ
Department of Burn, First Military Medical College.
D000328:Adult; D002056:Burns / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011869:Radioligand Assay; D011957:Receptors, Opioid / Q000378:metabolism*; D013601:T-Lymphocytes / Q000378:metabolism*; D001615:beta-Endorphin / Q000378:metabolism*
D011957:Receptors, Opioid; D001615:beta-Endorphin