The bile acids binding of the fibre-rich fractions of three starchy legumes.
The bile acid binding to undigestible fibre has a significance on bile acids excretion. This was known to result in lowering blood cholesterol (for the use of cholesterol in bile acid formation) as well as reducing the colorectal cancer risk (through decreased formation of secondary bile acids). Compared to the model fibres Solka floc and carboxymethylcellulose (CMC), the investigated fibre fractions of lentils, broad beans and butter beans, were found to bind more cholic acid and chenodeoxycholic acid under conditions simulating the small intestine.
Elhardallou
S B
SB
Department of Food Science and Technology, University of Reading, U.K.
D001647:Bile Acids and Salts / Q000378:metabolism*; D001665:Binding Sites; D002635:Chenodeoxycholic Acid / Q000378:metabolism; D019826:Cholic Acid; D002793:Cholic Acids / Q000378:metabolism; D002845:Chromatography / Q000379:methods; D004043:Dietary Fiber / Q000378:metabolism*; D007887:Fabaceae / Q000378:metabolism*; D010946:Plants, Medicinal
D001647:Bile Acids and Salts; D002793:Cholic Acids; D004043:Dietary Fiber; D002635:Chenodeoxycholic Acid; D019826:Cholic Acid