[Clinical and histological findings in HCV-caused hepatitis].
58 cases of acute HCV-hepatitis were studied from the debut of acute illness and were followed up over 1-12 years. A mean three week's delay of anti-HCV IgG (Ortho) positivity was observed after the first manifestation of hepatitis. 70.6% relapsed and a chronic hepatitis developed in 37.9%. Seven patients died in HCV-hepatitis. Clinical, chemical, morphological features of HCV-hepatitis different from other viral hepatitis are demonstrated. Persistence of morphological signs of lobular hepatitis after even several months of subacute and chronic outcome has been found characteristic in HCV-hepatitis. Difficulties in interpretation of liver morphology are discussed. Simultaneous evaluation of clinical picture, laboratory markers and morphology is necessary to select cases for therapeutic trials.
Telegdy
L
L
Szent László Kórház, Budapest.
Kovács
M
M
Mihály
I
I
Nagy
E
E
Csibi
E
E
D000208:Acute Disease; D016174:Hepacivirus / Q000472:pathogenicity; D006526:Hepatitis C / Q000382:microbiology / Q000401:mortality / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology; D009336:Necrosis
Klinikai és histologiai megfigyeléseink hepatitis C vírus okozta hepatitisben.