[Combined small cell and "adenoid cystic" carcinoma of the uterine cervix].
Cervical carcinoma in a 49-year-old woman was resected and found to spread into parametrium. It consisted of a unique combination of adenoid cystic, squamous and small cell neuroendocrine structures. Small celled part revealed positivity with chromogranin A and neuron-specific enolase, neuroendocrine granules were argyrophilic and about 130 nm in diameter. Adenoid cystic and squamous parts were lacking of unambiguous neuroendocrine or myoepithelial differentiation. The patient died in 27 months due to generalization but only a small cell carcinoma without any heterogeneity was found in autopsy. Small cell and adenoid cystic carcinomas are rare and more malignant than usual cervical carcinomas.
Zámecník
M
M
Oddelenie patológie, NsP, Trencín.
Patriková
J
J
Mirejovský
P
P
Jakubovský
I
I
D003528:Carcinoma, Adenoid Cystic / Q000473:pathology*; D018288:Carcinoma, Small Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000473:pathology*
Kombinovaný malobunkový a "adenoidne cystický" karcinóm cervixu uteru.