The killing of Entamoeba histolytica by activated human eosinophils.
Unlike normal, opsonin aided human eosinophils, fMLP-activated human eosinophils are capable of destroying virulent E. histolytica. Opsonins are not required for this action, although they enhance the effect. Some activated eosinophils succumb in the action as well, probably victims of toxic products released by dying amebas. Activated eosinophils thus appear to resemble activated macrophages in their dealing with this parasite.
López-Osuna
M
M
Division of Immunology, Subjefatura de Investigación, CMN-Siglo XXI, IMSS, México, DF.
Arellano
J
J
Giménez-Scherer
J A
JA
Kretschmer
R R
RR
D000328:Adult; D000818:Animals; D002470:Cell Survival; D004748:Entamoeba histolytica / Q000276:immunology / Q000472:pathogenicity; D004804:Eosinophils / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007106:Immune Sera; D008163:Luminescent Measurements; D009240:N-Formylmethionine Leucyl-Phenylalanine / Q000494:pharmacology; D014774:Virulence
D007106:Immune Sera; D009240:N-Formylmethionine Leucyl-Phenylalanine