title: The problem of ductal carcinoma in situ of the breast.
abstract: Ductal carcinoma in situ (DCIS) of the breast is a problem seen with increasing frequency as a result of the more widespread use of mammography. Treatment options are discussed together with on-going clinical trials seeking to determine the role of radiotherapy and tamoxifen in breast conservation treatment for DCIS.
authors.affiliation: ICRF Clinical Oncology Unit, Guy's Hospital, London, U.K.
authors.forename: I S
authors.initials: IS
authors.lastname: Fentiman
mesh_terms: D001706:Biopsy; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D002278:Carcinoma in Situ / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental; D009367:Neoplasm Staging; D013629:Tamoxifen / Q000008:administration & dosage
chemical_list: D013629:Tamoxifen