title: Apparent sufficiency of a dual-specificity tyrosine/threonine kinase for activation of MAP kinase poses new questions for the dual-phosphorylation mechanism.
authors.affiliation: Department of Internal Medicine and Pharmacology, University of Virginia, Charlottesville 22908.
authors.forename: J
authors.initials: J
authors.lastname: Wu
authors.forename: A J
authors.initials: AJ
authors.lastname: Rossomando
authors.forename: J
authors.initials: J
authors.lastname: Horng-Her
authors.forename: M J
authors.initials: MJ
authors.lastname: Weber
authors.forename: T W
authors.initials: TW
authors.lastname: Sturgill
mesh_terms: D000818:Animals; D017871:Calcium-Calmodulin-Dependent Protein Kinases; D004789:Enzyme Activation; D006801:Humans; D019950:Mitogen-Activated Protein Kinase 1; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D011505:Protein-Tyrosine Kinases / Q000378:metabolism*
chemical_list: D011494:Protein Kinases; D011505:Protein-Tyrosine Kinases; D017346:Protein Serine-Threonine Kinases; D017871:Calcium-Calmodulin-Dependent Protein Kinases; D019950:Mitogen-Activated Protein Kinase 1