Primary small cell carcinoma of the urinary bladder. Report of a case with immunohistochemical analyses.
A case of primary small cell carcinoma of the urinary bladder is reported. The light-microscopic diagnosis was supported by immunoreactivity for HISL-19 (marker for peptide-hormone-producing cells) and for neuron-specific enolase (NSE), demonstrating the neuroendocrine differentiation of this rare bladder tumor. Serum NSE, which was significantly elevated, can be a marker for disease extent and response to therapy.
Höbarth
K
K
Department of Urology, Medical School, University of Vienna, Austria.
Wrba
F
F
Hofbauer
J
J
D000911:Antibodies, Monoclonal; D018288:Carcinoma, Small Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D010751:Phosphopyruvate Hydratase; D001749:Urinary Bladder Neoplasms / Q000473:pathology*
D000911:Antibodies, Monoclonal; D010751:Phosphopyruvate Hydratase