title: Effects of amphetamine on the development of MTV-induced mammary tumors in female mice.
abstract: Female C3H/He mice carrying the mammary tumor virus (MTV) were monitored for mammary tumor incidence and latent periods while submitted to a daily subcutaneous injection with amphetamine (0,4 mg/kg/day). Results show that amphetamine caused an increase in incidence and a decrease in latency of tumors compared with placebo. There was also appreciated a correlation with the lethality of mice.
authors.affiliation: Department of Pharmacology, School of Medicine, University of Santiago, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Freire-Garabal
authors.forename: M J
authors.initials: MJ
authors.lastname: Núñez
authors.forename: J L
authors.initials: JL
authors.lastname: Balboa
authors.forename: J A
authors.initials: JA
authors.lastname: Suárez
authors.forename: A
authors.initials: A
authors.lastname: Gallego
authors.forename: A
authors.initials: A
authors.lastname: Belmonte
mesh_terms: D000661:Amphetamine / Q000008:administration & dosage / Q000009:adverse effects*; D000818:Animals; D004334:Drug Administration Schedule; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced* / Q000382:microbiology / Q000517:prevention & control; D008324:Mammary Tumor Virus, Mouse / Q000187:drug effects* / Q000502:physiology; D051379:Mice; D008809:Mice, Inbred C3H; D014779:Virus Replication / Q000187:drug effects
chemical_list: D000661:Amphetamine