The prohormone and proprotein processing enzymes PC1 and PC2: structure, selective cleavage of mouse POMC and human renin at pairs of basic residues, cellular expression, tissue distribution, and mRNA regulation.
Seidah
N G
NG
Clinical Research Institute of Montreal, Université de Montréal, Quebec, Canada.
Day
R
R
Benjannet
S
S
Rondeau
N
N
Boudreault
A
A
Reudelhuber
T
T
Schafer
M K
MK
Watson
S J
SJ
Chrétien
M
M
D000818:Animals; D001483:Base Sequence; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D011333:Pro-Opiomelanocortin / Q000378:metabolism*; D045664:Proprotein Convertase 1; D045706:Proprotein Convertase 2; D043484:Proprotein Convertases; D012333:RNA, Messenger / Q000096:biosynthesis*; D012083:Renin / Q000378:metabolism*; D012697:Serine Endopeptidases / Q000096:biosynthesis / Q000235:genetics*
D012333:RNA, Messenger; D011333:Pro-Opiomelanocortin; D043484:Proprotein Convertases; D012697:Serine Endopeptidases; C473656:Pcsk1 protein, mouse; D045664:Proprotein Convertase 1; D045706:Proprotein Convertase 2; D012083:Renin