Personality features and platelet 3H-imipramine binding.
In an attempt to provide further information on the functions of the serotonergic system in humans, we investigated the possible correlation between a peripheral serotonergic marker, such as platelet 3H-imipramine binding, and the Minnesota Multiphasic Personality Inventory (MMPI) items and scales in a group of 20 healthy subjects. The results showed the presence of significant positive correlation between the maximum binding capacity, a measure of the number of 3H-imipramine sites, and 17 MMPI items suggestive of personality features of self-certainty, feeling of well-being and sense of reality.
Castrogiovanni
P
P
Institute of Psychiatry, University of Pisa, Italy.
Maremmani
I
I
Di Muro
A
A
Rotondo
A
A
Marazziti
D
D
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001792:Blood Platelets / Q000378:metabolism*; D002352:Carrier Proteins; D005260:Female; D006801:Humans; D007099:Imipramine / Q000097:blood / Q000378:metabolism*; D008950:MMPI; D008297:Male; D010551:Personality; D010555:Personality Inventory; D011955:Receptors, Drug; D017981:Receptors, Neurotransmitter / Q000378:metabolism; D012701:Serotonin / Q000097:blood*
D015415:Biomarkers; D002352:Carrier Proteins; D011955:Receptors, Drug; D017981:Receptors, Neurotransmitter; C027775:imipramine receptor; D012701:Serotonin; D007099:Imipramine