Lymphoma mimics cytomegalovirus-induced hepatitis in a heart transplant recipient.
A 56-year-old diabetic man underwent heart transplantation for end-stage ischemic heart disease; fever, progressive thrombocytopenia, and hepatitis developed 8 weeks after transplantation. Cytomegalovirus was cultured from the serum buffy coat. In spite of therapy with high-dose ganciclovir sodium, the patient died on the seventy-seventh postoperative day. Autopsy revealed a previously unsuspected high-grade B-cell lymphoma with extensive hepatic replacement.
Dec
G W
GW
Cardiac Transplant Program, Massachusetts General Hospital, Boston 02114.
Semigran
M J
MJ
Vlahakes
G
G
Southern
J
J
Fallon
J T
JT
D003586:Cytomegalovirus Infections / Q000175:diagnosis*; D003937:Diagnosis, Differential; D016027:Heart Transplantation; D006525:Hepatitis, Viral, Human / Q000175:diagnosis*; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000175:diagnosis*; D016393:Lymphoma, B-Cell / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged