The structure and function of Na+ channels.
The past year has seen major advances in our understanding of voltage-gated ion channels through a powerful combination of patch-clamp and molecular biological techniques. These approaches have identified regions (in some cases single amino acid residues) that are essential for voltage-dependent activation and inactivation, lining of the pore, and regulation of channel function.
Stühmer
W
W
Abteilung Membranebiophysik, Max Planck Institute für Biophysikalische Chemie, Göttingen, Germany.
Parekh
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AB
D000818:Animals; D006801:Humans; D015640:Ion Channel Gating; D015222:Sodium Channels / Q000502:physiology*
D015222:Sodium Channels