[Sister chromatid exchanges in lymphocytes of patients with gynecological malignancies].
The frequency of SCE in the peripheral blood lymphocytes of 30 patients with gynecological malignancies was investigated. The frequency of SCE was found to be 5.37 +/- 0.44, 5.30 +/- 0.35 and 3.76 +/- 0.38 respectively in the patients before and after chemotherapy and in the control cases. The SCE values deviated significantly from those of control, and were not related to the staging of the tumor. The study suggested the possibility of utilizing SCE as a cytogenetic indicator in some malignant tumors.
Li
Z X
ZX
Lu Jun People's Hospital, Beijing Medical University.
D002277:Carcinoma / Q000235:genetics*; D016889:Endometrial Neoplasms / Q000235:genetics; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000235:genetics*; D011247:Pregnancy; D012854:Sister Chromatid Exchange; D014328:Trophoblastic Neoplasms / Q000235:genetics; D014594:Uterine Neoplasms / Q000235:genetics