Histopathology and immunohistopathology of lymph nodes of the first autopsy with HIV positivity in China.
Nineteen lymph nodes of a HIV-positive boy were studied histologically and immunohistologically. According to Stutte's classification of HIV-related lymphadenopathy, 84% of the lymph nodes were at the third or fourth stages in relation to clinical status ARC/AIDS. Lymph follicle atrophy, angiogenesis, histiocytic proliferation and destruction of the normal reticulum frame were observed. Immunohistochemical studies showed most of the remaining lymphocytes to be T cells and changes in the distribution of S-100 positive cells. Ki 1 positive cells existed mainly at the second stage. The significance of these changes is discussed.
Lai
M D
MD
Department of Pathology, Zhejiang Medical University, Hangzhou.
Xu
Y H
YH
Dai
D
D
Tang
D J
DJ
Han
Y J
YJ
D015703:Antigens, CD / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000032:analysis*; D006679:HIV Seropositivity / Q000276:immunology / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D017730:Ki-1 Antigen; D008198:Lymph Nodes / Q000276:immunology / Q000378:metabolism / Q000473:pathology*; D008297:Male; D009418:S100 Proteins / Q000032:analysis
D015703:Antigens, CD; D000951:Antigens, Neoplasm; D017730:Ki-1 Antigen; D009418:S100 Proteins