title: [Trichosporon capitatum septicemia. Apropos of 5 cases].
abstract: Invasive Trichosporon capitatum infections are seldom reported. We present here five cases of septicemia. All patients had an acute myeloblastic leukemia and were severely neutropenic. They have also been treated before the onset of the fungal infection with broad-spectrum antibiotherapy and also with an oral azole antifungal agent. The role of this antifungal therapy in the development of T. capitatum infection is discussed. The prognosis of T. capitatum infections is severe. Eight of the 10 published cases had a fatal outcome and one of our patients died of the fungal infection in spite of the treatment.
authors.affiliation: Service d'Onco-Hématologie, Hôpital de Hautepierre, Strasbourg.
authors.forename: R
authors.initials: R
authors.lastname: Herbrecht
authors.forename: K L
authors.initials: KL
authors.lastname: Liu
authors.forename: H
authors.initials: H
authors.lastname: Koenig
authors.forename: J
authors.initials: J
authors.lastname: Waller
authors.forename: P
authors.initials: P
authors.lastname: Dufour
authors.forename: L
authors.initials: L
authors.lastname: Marcellin
authors.forename: F
authors.initials: F
authors.lastname: Maloisel
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D016026:Bone Marrow Transplantation; D005260:Female; D006086:Graft vs Host Disease / Q000276:immunology; D006801:Humans; D016867:Immunocompromised Host; D007951:Leukemia, Myeloid / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000150:complications* / Q000188:drug therapy; D009503:Neutropenia / Q000150:complications; D011379:Prognosis; D018805:Sepsis / Q000188:drug therapy / Q000209:etiology*; D014250:Trichosporon
chemical_list: D000666:Amphotericin B
vernacular_title: Septicémies à Trichosporon capitatum. A propos de 5 observations.