title: Characterization of the adherence of Porphyromonas gingivalis to oral streptococci.
abstract: Adherence of Porphyromonas gingivalis to strains of Streptococcus sanguis and Streptococcus mitis deposited on nitrocellulose paper was investigated. A variety of laboratory strains and clinical isolates of P. gingivalis bound to both S. sanguis and S. mitis. Binding of P. gingivalis to all but one of the streptococci was not inhibited by salivary molecules. Pretreatment of P. gingivalis with periodate and pretreatment of S. sanguis and S. mitis with pronase decreased binding, suggesting that adherence may be mediated by a protein on the streptococci interacting with a carbohydrate on P. gingivalis. Binding was not inhibited by a selection of simple sugars. The ability to adhere to early plaque bacteria such as S. sanguis and S. mitis may be important in the colonization of the mouth by P. gingivalis.
authors.affiliation: School of Dentistry, University of Washington, Seattle.
authors.forename: R J
authors.initials: RJ
authors.lastname: Lamont
authors.forename: S G
authors.initials: SG
authors.lastname: Hersey
authors.forename: B
authors.initials: B
authors.lastname: Rosan
mesh_terms: D001422:Bacterial Adhesion; D001425:Bacterial Outer Membrane Proteins; D008828:Microbiological Techniques; D011135:Polysaccharides, Bacterial; D016966:Porphyromonas gingivalis / Q000502:physiology*; D013291:Streptococcus / Q000502:physiology; D013298:Streptococcus sanguis / Q000502:physiology; D013559:Symbiosis
chemical_list: D001425:Bacterial Outer Membrane Proteins; D011135:Polysaccharides, Bacterial