[Human hybridoma neutralizing antibodies to the herpes simplex virus].
Human hybridoma cells producing monoclonal antibodies to human herpes simplex virus were generated. The antibody produced by the hybrid cells interacted with herpes virus types I and II in enzyme immunoassay and complement fixation test, had neutralizing activity both in vivo and in vitro. These human monoclonal antibodies may be used for immunotherapy of herpes virus infection.
Kushch
A A
AA
Tugizov
Sh M
ShM
Terletskaia
E N
EN
Posevaia
T A
TA
Nikitina
A A
AA
L'vov
N D
ND
Barinskiĭ
I F
IF
D000911:Antibodies, Monoclonal / Q000032:analysis / Q000276:immunology* / Q000302:isolation & purification; D000914:Antibodies, Viral / Q000032:analysis / Q000276:immunology* / Q000302:isolation & purification; D001402:B-Lymphocytes / Q000276:immunology / Q000382:microbiology; D002459:Cell Fusion / Q000276:immunology; D002460:Cell Line; D002472:Cell Transformation, Viral; D006561:Herpes Simplex / Q000382:microbiology; D004854:Herpesvirus 4, Human; D006801:Humans; D006825:Hybridomas / Q000276:immunology*; D015151:Immunoblotting; D009500:Neutralization Tests; D018139:Simplexvirus / Q000276:immunology* / Q000302:isolation & purification
D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral
Chelovecheskie gibridomnye neĭtralizuiushchie antitela k virusu prostogo gerpesa.