[The transport system that pumps monosaccharides from enterocytes across the basolateral membrane].
Using a new, in vitro, experimental approach the transport of glucose, galactose, fructose and glycine in seroso-mucosal direction in the small intestine, was studied under different modes of oxygenation. In case of monosaccharides under the oxygenation from serosal surface, the substrate concentration is lower in the small intestine tissue than under anoxia. The effect of the oxygenation from serosal surface on the galactose transport was shown to be sensitive to absence of sodium ions, ouabain, phloretin, and not sensitive to phlorizin. The data obtained corroborate the hypothesis of the existence of a mechanism pumping off monosaccharides enterocytes through the basolateral membrane.
Gromova
L V
LV
Ugolev
A M
AM
D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects / Q000502:physiology; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism; D007421:Intestine, Small / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D009005:Monosaccharides / Q000378:metabolism*; D010101:Oxygen Consumption / Q000187:drug effects / Q000502:physiology; D051381:Rats; D012704:Serous Membrane / Q000187:drug effects / Q000378:metabolism; D013997:Time Factors
D009005:Monosaccharides
Transportnaia sistema, otkachivaiushchaia monosakharidy iz énterotsitov cherez bazolateral'nuiu membranu.