title: Sumatriptan in chronic cluster headache: results of continuous treatment for eleven months.
abstract: A 32-year-old man received a total of 480 injections of subcutaneous sumatriptan 6 mg for the treatment of acute attacks of chronic cluster headache over an eleven-month period. Over 90% of the attacks resolved within 10 min of treatment (average 6.8 +/- 3.4). As a comparison, the average duration of 61 attacks occurring over the same period, but not treated with sumatriptan, was 56.1 +/- 20.8 min. This difference was highly significant. There was no clinical evidence of tachyphylaxis, and there were no adverse effects. This is the first report of a long-term treatment of cluster headache with sumatriptan. It is concluded that sumatriptan in this case was an effective and well-tolerated treatment for cluster headache.
authors.affiliation: Department of Neurology, Söder Hospital, Stockholm, Sweden.
authors.forename: K
authors.initials: K
authors.lastname: Ekbom
authors.forename: E
authors.initials: E
authors.lastname: Waldenlind
authors.forename: J
authors.initials: J
authors.lastname: Cole
authors.forename: A
authors.initials: A
authors.lastname: Pilgrim
authors.forename: A
authors.initials: A
authors.lastname: Kirkham
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003027:Cluster Headache / Q000188:drug therapy*; D004311:Double-Blind Method; D006801:Humans; D007211:Indoles / Q000008:administration & dosage / Q000627:therapeutic use*; D007279:Injections, Subcutaneous; D008297:Male; D013449:Sulfonamides / Q000008:administration & dosage / Q000627:therapeutic use*; D018170:Sumatriptan; D013997:Time Factors
chemical_list: D007211:Indoles; D013449:Sulfonamides; D018170:Sumatriptan