Sequence of bovine interleukin 7.
We report the cloning and the sequencing of a cDNA coding for the mature bovine interleukin 7 (IL-7). The clone was isolated from a bovine leukemia virus (BLV)-induced B cell-lymphosarcoma cDNA library. The 5' non-coding sequence and the sequence of the signal peptide were obtained from a clone isolated from a bovine genomic library. The entire bovine IL-7 protein is 176 amino acids long and shows 75 and 65% homology to published sequences of human and murine IL-7, respectively.
Cludts
I
I
Laboratoire de Chimie Biologique, Université Libre de Bruxelles, Rhode-St-Genèse, Belgium.
Droogmans
L
L
Cleuter
Y
Y
Kettmann
R
R
Burny
A
A
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002417:Cattle; D003001:Cloning, Molecular; D004247:DNA; D016583:Enzootic Bovine Leukosis / Q000235:genetics; D006801:Humans; D015851:Interleukin-7 / Q000235:genetics*; D001909:Leukemia Virus, Bovine / Q000378:metabolism; D008969:Molecular Sequence Data; D021382:Protein Sorting Signals / Q000235:genetics; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid
D015851:Interleukin-7; D021382:Protein Sorting Signals; D004247:DNA