title: [Coronary pathology after heart transplantation].
abstract: Graft coronary disease is a frequent and devastating complication with rapid development after heart transplantation. Until now, non-invasive and invasive methods have proved to be insensitive in the prediction and detection of the early stages of this disease. Conventional arteriography is considered as the only reliable means of diagnosis, but it remains insensitive in the accurate evaluation of the severity of graft coronary lesions (obliterative, diffuse and distal lesions). Precise quantitation of coronary lumen changes may be a sensitive method for the accurate evaluation of graft coronary disease and help in the understanding of the natural course of development of this disease. The pathogenesis of the disease is still unclear. It is possible that graft coronary disease is a consequence of non-treated low-grade cellular rejections. In most cases, retransplantation must be considered as the unique solution.
authors.affiliation: Service de Chirurgie cardiovasculaire, Hôpital de la Pitié, Paris.
authors.forename: M
authors.initials: M
authors.lastname: Desruennes
authors.forename: G
authors.initials: G
authors.lastname: Drobinski
authors.forename: G
authors.initials: G
authors.lastname: Chomette
authors.forename: B
authors.initials: B
authors.lastname: Autran
authors.forename: A
authors.initials: A
authors.lastname: Pavie
authors.forename: P
authors.initials: P
authors.lastname: Léger
authors.forename: I
authors.initials: I
authors.lastname: Gandjbakhch
authors.forename: F
authors.initials: F
authors.lastname: Jault
authors.forename: Y
authors.initials: Y
authors.lastname: Grosgogeat
authors.forename: C
authors.initials: C
authors.lastname: Cabrol
mesh_terms: D017023:Coronary Angiography / Q000379:methods*; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D003586:Cytomegalovirus Infections / Q000209:etiology; D006084:Graft Rejection; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D011183:Postoperative Complications; D012086:Reoperation; D012307:Risk Factors; D013997:Time Factors
vernacular_title: Pathologie coronaire après transplantation cardiaque.