Hemimegalencephaly and normal intellectual development.
Hemimegalencephaly is a rare congenital malformation characterised by overgrowth of one hemisphere. Although it is commonly thought to be associated with neurological deficits, developmental delay, and intractable epilepsy, the clinical expression of hemimegalencephaly, can vary widely. This patient was neurologically and neuropsychologically normal apart from rare partial seizures.
Fusco
L
L
Bambino Gesù Children's Hospital, National Medical Research Institute, Rome, Italy.
Ferracuti
S
S
Fariello
G
G
Manfredi
M
M
Vigevano
F
F
D000328:Adult; D001921:Brain / Q000002:abnormalities* / Q000503:physiopathology; D002540:Cerebral Cortex / Q000002:abnormalities / Q000503:physiopathology; D004292:Dominance, Cerebral / Q000502:physiology*; D004830:Epilepsy, Tonic-Clonic / Q000503:physiopathology*; D006801:Humans; D007360:Intelligence / Q000502:physiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination; D009435:Synaptic Transmission / Q000502:physiology; D014057:Tomography, X-Ray Computed