Fatal disseminated infection with human herpesvirus-6.
A 13-month-old immunocompetent girl had fever, rash, and multisystem disease, and she eventually died of cardiac failure. Autopsy revealed intracellular viral inclusions of the herpesvirus group, with results of in situ hybridization positive for human herpesvirus-6. This is apparently the first case of fatal disseminated herpesvirus-6 infection.
Prezioso
P J
PJ
Department of Pediatrics, New York University School of Medicine, New York.
Cangiarella
J
J
Lee
M
M
Nuovo
G J
GJ
Borkowsky
W
W
Orlow
S J
SJ
Greco
M A
MA
D005077:Exanthema Subitum / Q000382:microbiology*; D005260:Female; D006566:Herpesviridae Infections / Q000453:epidemiology* / Q000382:microbiology; D015654:Herpesvirus 6, Human / Q000302:isolation & purification*; D006801:Humans; D007181:Inclusion Bodies, Viral / Q000382:microbiology; D007223:Infant; D008214:Lymphocytes / Q000382:microbiology; D008854:Microscopy, Electron; D009693:Nucleic Acid Hybridization; D013154:Spleen / Q000382:microbiology