[Thrombosis of superior longitudinal sinus and pulmonary embolism in nephrotic syndrome].
The authors report on the case of a child with the nephrotic syndrome complicated by thrombosis of superior longitudinal sinus, bilateral massive pulmonary embolism resulting in a sudden death. A dramatic deficiency in factor XII was demonstrated; the pathophysiology and management of such an abnormality are discussed.
Delmas
M C
MC
Unité de néphrologie pédiatrique, hôpital E Herriot, Lyon, France.
Cochat
P
P
Ranchin
B
B
Négrier
C
C
Barre
P
P
Bouvier
R
R
David
L
L
D002675:Child, Preschool; D003520:Cyclophosphamide / Q000627:therapeutic use; D003645:Death, Sudden / Q000209:etiology; D005175:Factor XII Deficiency / Q000209:etiology; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009404:Nephrotic Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000209:etiology*; D011859:Radiography; D012851:Sinus Thrombosis, Intracranial / Q000000981:diagnostic imaging / Q000209:etiology*
D003520:Cyclophosphamide; D008775:Methylprednisolone
Thrombose du sinus longitudinal supérieur et embolie pulmonaire au cours d'une néphrose.