title: [Transvenous hepatic biopsy in patients with blood coagulation disorders].
abstract: Severe clotting defects represent the main contraindication to percutaneous liver biopsy. A transvenous liver puncture technique has been developed for patients suffering from blood coagulation disorders. This approach was attempted in 17 of 148 consecutive patients (12%) in whom a needle liver biopsy was indicated. Hepatic tissue samplings were successfully obtained in 16 subjects. The mean size of the specimens was 7 mm. The clinical diagnosis or therapy were modified in 7 patients when the histopathology report was available. No complications related to the procedure occurred. Our early experience suggests that transvenous liver biopsy is indicated in one/ninth of cases in whom hepatic tissue sample is required for diagnosis. This technique is safe, and it has a high success rate to provide liver tissue samples.
authors.affiliation: Centro de Gastroenterología, Hospital Clínico, Universidad de Chile, Santiago.
authors.forename: J
authors.initials: J
authors.lastname: Chesta
authors.forename: G
authors.initials: G
authors.lastname: Smok
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods*; D001778:Blood Coagulation Disorders / Q000150:complications*; D000075202:Contraindications; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged
vernacular_title: Biopsia hepatica transvenosa en pacientes con defectos de la coagulacion sanguinea.