[New aspects of adoptive immunochemotherapy in disseminated forms of cancer].
A method of autolymphochemotherapy was developed based on administration of a "therapeutic" course of chemotherapy following cytotoxic treatment of a large amount (1.5-2 l) of central lymph obtained by external drainage of the thoracic duct. Immediate results of treatment of 15 patients with advanced breast, lung (non-small-cell) and ovarian cancer with various degree of chemoresistance are presented. Marked response was observed in 14 cases. It seems justified to use the method for the treatment of locally advanced cancer.
Normantovich
V A
VA
Laktionov
K P
KP
Kadagidze
Z G
ZG
Savel'eva
E V
EV
Khlebnov
A V
AV
Vysotskaia
I V
IV
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000628:therapy*; D002289:Carcinoma, Non-Small-Cell Lung / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D016219:Immunotherapy, Adoptive / Q000379:methods*; D008175:Lung Neoplasms / Q000628:therapy*; D008196:Lymph / Q000276:immunology; D016246:Lymphocytes, Tumor-Infiltrating / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012074:Remission Induction; D013724:Teratoma / Q000628:therapy; D013736:Testicular Neoplasms / Q000628:therapy
Novye aspekty adoptivnoĭ immunokhimioterapii rasprostranennykh form raka.