Neuropathological findings in cerebral B-protein amyloidosis. Differences and similarities in those cases presenting as a cerebral hemorrhage and those presenting as a dementia of the Alzheimer type.
Cerebral hemorrhages with amyloidosis and dementia of the Alzheimer type have many neuropathological findings in common, but there are also marked quantitative and qualitative differences. That makes it highly improbably that the B-protein amyloid depositions itself are the direct cause of extensive neuronal death and dementia in DAT.
Bots
G T
GT
Department of Pathology, State University of Leiden, The Netherlands.
D000544:Alzheimer Disease / Q000235:genetics / Q000473:pathology*; D016229:Amyloid beta-Peptides / Q000648:ultrastructure*; D016657:Cerebral Amyloid Angiopathy / Q000235:genetics / Q000473:pathology*; D002536:Cerebral Arteries / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000235:genetics / Q000473:pathology*; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D009410:Nerve Degeneration / Q000502:physiology*
D016229:Amyloid beta-Peptides