title: Mechanisms of protective immunity in Hymenolepis nana/mouse model.
abstract: Some immunological and parasitological aspects related to the infection of Hymenolepsis nana in mice are summarized in this review, focusing on the immune effector mechanisms involved in this host/parasite relationship. H. nana is a small cestode tapeworm of man and mice. A primary egg-infection determines within few days a strong immunity. Immunity elicited by low-level primary infection is effective as a high-level infection. The protective role of both humoral and cell-mediated immunity is summarized. The histological findings demonstrate that eosinophils and mast-cells are implicated as effector cells. This review is an attempt to re-examine, at low-level infection, the immune mechanisms in H. nana/mouse model.
authors.affiliation: Istituto di Patologia Sperimentale, Università degli Studi di Cagliari.
authors.forename: G
authors.initials: G
authors.lastname: Bortoletti
authors.forename: F
authors.initials: F
authors.lastname: Gabriele
authors.forename: C
authors.initials: C
authors.lastname: Palmas
mesh_terms: D000818:Animals; D004804:Eosinophils / Q000276:immunology; D006790:Host-Parasite Interactions; D006925:Hymenolepiasis / Q000276:immunology*; D006926:Hymenolepis / Q000254:growth & development / Q000276:immunology*; D007249:Inflammation; D007411:Intestinal Diseases, Parasitic / Q000276:immunology* / Q000469:parasitology; D007413:Intestinal Mucosa / Q000276:immunology; D008407:Mast Cells / Q000276:immunology; D051379:Mice / Q000276:immunology / Q000469:parasitology*; D008815:Mice, Inbred Strains / Q000276:immunology / Q000469:parasitology