title: Peripheral T-cell lymphoma involving the placenta.
abstract: BACKGROUND
  Placental involvement by maternal malignant lymphoma is a rare complication of pregnancy.
  
  
  METHODS
  The case of a 29-year-old woman found to have placental involvement by peripheral T-cell lymphoma (PTCL) diagnosed by morphologic study, immunoperoxidase stains, and molecular genetic studies is reported.
  
  
  RESULTS
  The lymphoma was pathologic Stage IVB and although there were no adverse consequences for the child, but the neoplasm progressed rapidly during the postpartum period.
  
  
  CONCLUSIONS
  The clinical course suggested that the immunologic changes of the pregnancy exerted a lymphoma-suppressive effect on the lymphoma. The authors know of no other report of a patient with placental involvement by PTCL.
authors.affiliation: Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905.
authors.forename: P J
authors.initials: PJ
authors.lastname: Kurtin
authors.forename: T A
authors.initials: TA
authors.lastname: Gaffey
authors.forename: T M
authors.initials: TM
authors.lastname: Habermann
mesh_terms: D000328:Adult; D015703:Antigens, CD / Q000032:analysis; D005260:Female; D015333:Gene Rearrangement, beta-Chain T-Cell Antigen Receptor / Q000502:physiology; D015334:Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor / Q000502:physiology; D006801:Humans; D007150:Immunohistochemistry; D008228:Lymphoma, Non-Hodgkin / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D016411:Lymphoma, T-Cell, Peripheral / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D010922:Placenta Diseases / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D049590:Postpartum Period; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000276:immunology / Q000473:pathology* / Q000503:physiopathology
chemical_list: D015703:Antigens, CD