[Responses of neurons in the somato-sensory area I to noxious electric stimulation of nervus peroneus communis. The study of intracellular potentials].
Noxious electric stimulation of nervus peroneus communis (PN) results in pain. It hasn't been reported that the neurons in somatosensory area I (SI) may respond to the noxious stimulation. In this paper, using intracellular microelectrode technique, we have studied the responses of neurons in SI to noxious electric stimulating PN. 33 neurons were recorded in 18 cats. 16 neurons were related with the noxious stimulation. The responses of these neurons to noxious stimulation were mainly inhibitory postsynaptic potentials (IPSP). Some neurons responded with two IPSPs. A few neurons responded with EPSP (Excitatory postsynaptic potential)-IPSPs. The latencies of the first IPSPs were short (8.25 +/- 5.90ms) and showed that the first IPSPs might be induced by the input of A beta fiber. The latencies of the second IPSPs (In the neurons with two IPSPs) were long (60.33 +/- 6.62 ms) and showed that the second IPSPs might be induced by the input of A delta fiber. Above results show that: 1) SI neurons can respond to the noxious electric stimulation of PN. 2) The responses of SI neurons to the noxious stimulation were mainly IPSPs. 3) The second IPSPs might be related with pain.
Sha
L
L
Department of Neurophysiology, China Medical University, Shenyang, Liaoning.
Ding
W
W
Teng
G
G
D000818:Animals; D004558:Electric Stimulation; D005071:Evoked Potentials; D005260:Female; D008297:Male; D009474:Neurons / Q000502:physiology; D009619:Nociceptors / Q000502:physiology*; D010543:Peroneal Nerve / Q000502:physiology*; D011817:Rabbits; D013003:Somatosensory Cortex / Q000502:physiology*