title: Enteric Clostridium perfringens infection associated with parvoviral enteritis in dogs: 74 cases (1987-1990).
abstract: Parvovirus infection was confirmed by fluorescent antibody staining of or viral isolation from specimens of small intestine in 181 (17%) of 1,110 dogs necropsied between July 1, 1987 and Dec 31, 1990. Clostridium perfringens was isolated from 74 (69%) of 108 dogs with parvovirus infection from which specimens of jejunum also had been obtained for culture of anaerobic bacteria. Gram-positive bacilli in association with focal to diffuse necrosis of the superficial portions of the villi were observed in histologic sections of specimens of small intestine from 56 (98%) of 57 dogs from which parvovirus and C perfringens had been identified. These findings indicate that C perfringens frequently proliferates in dogs with parvovirus infection.
authors.affiliation: Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri-Columbia 65205.
authors.forename: J
authors.initials: J
authors.lastname: Turk
authors.forename: W
authors.initials: W
authors.lastname: Fales
authors.forename: M
authors.initials: M
authors.lastname: Miller
authors.forename: L
authors.initials: L
authors.lastname: Pace
authors.forename: J
authors.initials: J
authors.lastname: Fischer
authors.forename: G
authors.initials: G
authors.lastname: Johnson
authors.forename: J
authors.initials: J
authors.lastname: Kreeger
authors.forename: S
authors.initials: S
authors.lastname: Turnquist
authors.forename: L
authors.initials: L
authors.lastname: Pittman
authors.forename: A
authors.initials: A
authors.lastname: Rottinghaus
mesh_terms: D000818:Animals; D003015:Clostridium Infections / Q000209:etiology / Q000662:veterinary*; D003016:Clostridium perfringens / Q000302:isolation & purification*; D003967:Diarrhea / Q000150:complications / Q000662:veterinary; D004283:Dog Diseases / Q000209:etiology*; D004285:Dogs; D004751:Enteritis / Q000150:complications / Q000662:veterinary*; D010321:Parvoviridae / Q000302:isolation & purification; D010322:Parvoviridae Infections / Q000150:complications / Q000662:veterinary*; D012189:Retrospective Studies