[Minipulses of cyclophosphamide in the treatment of dermatopolymyositis with lung involvement].
A new scheme for the treatment of dermatopolymyositis with pulmonary fibrosis not responding to corticosteroid therapy is presented. Monthly endovenous administration of a small dose of cyclophosphamide is advocated. Two patients with dermatopolymyositis not responding to prednisone were treated for two years with small doses of cyclophosphamide given monthly after which recovered from muscular and pulmonary involvement showing at present normal clinical parameters.
Takayasu
V
V
Departamento de Clínica Médica, Faculdade de Medicina, Universidade de São Paulo.
Hirose-Pastor
E
E
Fuller
R
R
Vilar
M C
MC
Yoshinari
N
N
Cossermelli
W
W
D000328:Adult; D002908:Chronic Disease; D003520:Cyclophosphamide / Q000008:administration & dosage*; D003882:Dermatomyositis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D011658:Pulmonary Fibrosis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D012074:Remission Induction; D013997:Time Factors
D003520:Cyclophosphamide
Mini-pulsos de ciclofosfamida no tratamento da dermatopolimiosite com envolvimento pulmonar.