Susceptibility of Aedes krombeini cell line to some arboviruses.
The susceptibility of the newly established Ae. krombeini cell line (NIVI-AK-453) to six arboviruses, belonging to four different families, was studied. Sindbis (SIND), Vesicular stomatitis (VSV) Chandipura (CHP) and African horse sickness (AHS) viruses multiplied in these cultures. A four-to-five-fold increase in the virus titres was observed. The maximum titre of SIND, VSV, CHP and AHS viruses were observed on 1st, 4th, 3rd and 10th post infection days, respectively. A steady and significant increase in the titre of AHS was observed over a period of ten days. The sandfly fever virus (SFV) and the tick-borne, Kaisodi virus did not multiply in the cultures.
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National Institute of Virology, Pune.
Sudeep
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Athawale
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D000330:Aedes / Q000382:microbiology*; D000356:African Horse Sickness Virus / Q000254:growth & development; D000818:Animals; D001103:Arboviruses / Q000254:growth & development*; D002460:Cell Line; D012209:Rhabdoviridae / Q000254:growth & development; D012845:Sindbis Virus / Q000254:growth & development; D014721:Vesicular stomatitis Indiana virus / Q000254:growth & development