Modular transposition and the dynamical structure of eukaryote regulatory evolution.
This paper examines a model in which transposable elements provide a modular architecture for the cellular genome, complemented by cellular recombinational transformations, arising in turn as a dynamical consequence of this modular structure. It is proposed that the ecology of transposable elements in a given organism is a function of recombinational protocols of the evolving cellular genome. In mammals this is proposed to involve coordinated meiosis-phased activation of LINEs, SINEs and retrogenes complemented by endogenous retroviral transfer between cells.
King
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Department of Mathematics and Statistics, University of Auckland, New Zealand.
D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D004251:DNA Transposable Elements; D005057:Eukaryotic Cells; D008322:Mammals / Q000235:genetics; D008957:Models, Genetic; D008969:Molecular Sequence Data; D011544:Pseudogenes; D011995:Recombination, Genetic; D012091:Repetitive Sequences, Nucleic Acid; D012190:Retroviridae / Q000235:genetics*; D013045:Species Specificity
D004251:DNA Transposable Elements