title: Fetal abdominal echogenic mass: an early sign of intrauterine cytomegalovirus infection.
abstract: BACKGROUND
  Recent advances in ultrasound technology have made it possible to diagnose fetal diseases much earlier in pregnancy. Reports have indicated that intrauterine infections, specifically cytomegalovirus, can be diagnosed prenatally by ultrasound.
  
  
  METHODS
  We encountered two cases in which cytomegalovirus infection was associated with hyperechoic areas in the fetal abdomen.
  
  
  CONCLUSIONS
  Hyperechoic areas in the fetal abdomen may be an early sign of fetal cytomegalovirus infection. Persistence of this sign may indicate a mild form of infection. Disappearance of these hyperechoic areas in subsequent ultrasonographic examinations and development of other ultrasound signs may indicate severe infection and poor prognosis.
authors.affiliation: Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia.
authors.forename: I
authors.initials: I
authors.lastname: Forouzan
mesh_terms: D000328:Adult; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000000981:diagnostic imaging*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000382:microbiology; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis; D016216:Ultrasonography, Prenatal