Oncogene transduction and activation.
This article explains what a transducing virus is, summarizes what is currently known about the origins of transducing viruses, considers the frequency of the generation of transducing viruses, and discusses how transduced oncogenes undergo activation. Most of the data come from work with avian leukosis viruses, as research with this group of viruses has set many of the precedents for work on retroviral transduction.
Robinson
H L
HL
University of Massachusetts Medical Center, Worcester 01655.
D000818:Animals; D002460:Cell Line; D015967:Gene Expression Regulation, Viral; D006801:Humans; D009857:Oncogenes; D012190:Retroviridae / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D012192:Retroviridae Infections / Q000209:etiology; D012449:Safety; D014161:Transduction, Genetic; D014412:Tumor Virus Infections / Q000209:etiology