title: [Recurrent fever episodes in an African child: diagnostic difficulties of trypanosomiasis in France].
abstract: A young Angolian boy who had emigrated to France at the age of 2, presented with a long history of fever. Gambian Trypanosomiasis was diagnosed with peculiar aspects: 1) evolution of adult sickness with a long hemolymphatic period (first stage) and a subacute worsening period with neurologic deficit and somnolence (second stage); 2) a possible post-transfusional contamination: the young boy, born in South Angola, a nor-highly endemic area, was transfused at the age of 10 months with the blood of a donor who was subsequently treated for Trypanosomiasis; 3) a suppurating adenopathy; 4) a predominance of IgG within the hypergammaglobulinemia while IgM are the predominant immunoglobulins in this affection; 5) a hepatic toxicity of Difluoromethylornithine.
authors.affiliation: Service de pédiatrie-génétique médicale, CHU de Rennes, Pontchaillou, France.
authors.forename: I
authors.initials: I
authors.lastname: Blanchot
authors.forename: A
authors.initials: A
authors.lastname: Dabadie
authors.forename: G
authors.initials: G
authors.lastname: Tell
authors.forename: C
authors.initials: C
authors.lastname: Guiguen
authors.forename: B
authors.initials: B
authors.lastname: Faugère
authors.forename: A M
authors.initials: AM
authors.lastname: Plat-Pelle
authors.forename: M
authors.initials: M
authors.lastname: Roussey
mesh_terms: D000810:Angola / Q000208:ethnology; D002675:Child, Preschool; D000518:Eflornithine / Q000627:therapeutic use; D005334:Fever / Q000209:etiology*; D005602:France; D006801:Humans; D008297:Male; D012008:Recurrence; D014353:Trypanosomiasis, African / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000518:Eflornithine
vernacular_title: Accès fébriles à répétition chez un enfant africain: difficultés diagnostiques d'une trypanosomiase en France.