title: The relationship of total serum cholesterol to coronary heart disease in older men. The Italian rural areas of the Seven Countries Study.
abstract: The relationship of serum cholesterol to the development of major coronary events (CHD) was studied in Italian rural cohorts of adult men aged 40-59 (n = 1672) and of older men aged 65-79 (n = 752) followed up for 5 years. In adult men both univariate and multivariate analysis (the latter with 4 or 5 covariates fed into the Cox model) showed a direct and significant relationship of cholesterol to CHD. In older men the univariate analysis confirmed a direct and significant relationship; for the multivariate analysis none of the considered factors was significantly predictive.
authors.affiliation: Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Menotti
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002784:Cholesterol / Q000097:blood*; D015331:Cohort Studies; D003327:Coronary Disease / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D012423:Rural Health; D012737:Sex Factors
chemical_list: D002784:Cholesterol