title: Agrin and the organization of the neuromuscular junction.
abstract: Agrin is a component of the synaptic extracellular matrix and may regulate the organization of acetylcholine receptors and other synaptic molecules in both synapse regeneration and development. Analyses of cDNAs encoding agrin define a number of structural domains, including regions of homology to laminin, Kazal protease inhibitors, and epidermal growth factor repeats.
authors.affiliation: Howard Hughes Medical Institute, Department of Molecular and Cellular Physiology, Beckman Center, Stanford University, California 94305.
authors.forename: F
authors.initials: F
authors.lastname: Rupp
authors.forename: W
authors.initials: W
authors.lastname: Hoch
authors.forename: J T
authors.initials: JT
authors.lastname: Campanelli
authors.forename: T
authors.initials: T
authors.lastname: Kreiner
authors.forename: R H
authors.initials: RH
authors.lastname: Scheller
mesh_terms: D018171:Agrin; D000818:Animals; D005109:Extracellular Matrix / Q000502:physiology; D006801:Humans; D009419:Nerve Tissue Proteins / Q000502:physiology*; D009469:Neuromuscular Junction / Q000502:physiology* / Q000648:ultrastructure; D011950:Receptors, Cholinergic / Q000502:physiology
chemical_list: D018171:Agrin; D009419:Nerve Tissue Proteins; D011950:Receptors, Cholinergic