title: Light does not induce an increase in cyclic-GMP content of squid or Limulus photoreceptors.
abstract: Both slices of squid (Loligo) retinas and Limulus ventral photoreceptors, with or without prior stimulation by flashes of bright light, were rapidly frozen and analysed for cyclic-GMP content by radioimmunoassay. Measurement of the freezing process indicated that freezing occurred at about 100 msec after the light flash. No significant changes in cyclic-GMP content were induced by light in either tissue. These data do not confirm previous reports that cyclic-GMP content of invertebrate photoreceptors is markedly increased by illumination.
authors.affiliation: Department of Ophthalmology and Visual Sciences, Washington University, St Louis, MO 63110.
authors.forename: J E
authors.initials: JE
authors.lastname: Brown
authors.forename: M
authors.initials: M
authors.lastname: Faddis
authors.forename: A
authors.initials: A
authors.lastname: Combs
mesh_terms: D000818:Animals; D006152:Cyclic GMP / Q000378:metabolism*; D049832:Decapodiformes; D006737:Horseshoe Crabs; D015544:Inositol 1,4,5-Trisphosphate / Q000378:metabolism; D008027:Light; D010775:Photic Stimulation; D010786:Photoreceptor Cells / Q000378:metabolism*; D011863:Radioimmunoassay; D015398:Signal Transduction / Q000502:physiology
chemical_list: D015544:Inositol 1,4,5-Trisphosphate; D006152:Cyclic GMP