Methyl 1,2,4,5,6,10b-hexahydro-8,9-methylenedioxy-2- oxobenzo[d]cyclopenta[b]azepine-4-carboxylate.
The title compound contains the tetracyclic A-B-C-E ring system of cephalotaxus alkaloids. Unexpectedly, the five-membered-ring plane is twisted 67.2 degrees from the aromatic ring plane and, like cephalotaxine, the seven-membered ring is oriented in a boat form with the nitrogen at the prow.
Robinson
P D
PD
Department of Geology, Southern Illinois University, Carbondale 62901.
Hua
D H
DH
Hong
Y
Y
Miao
S W
SW
D001552:Benzazepines / Q000138:chemical synthesis / Q000737:chemistry*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003460:Crystallization; D008968:Molecular Conformation; D015394:Molecular Structure; D014961:X-Ray Diffraction
D001552:Benzazepines; C077772:methyl 1,2,4,5,6,10b-hexahydro-8,9-methylenedioxy-2-oxobenzo(d)cyclopenta(b)azepine-4-carboxylate