The periodic paralyses.
These mysterious attacks of muscle weakness are difficult to treat because the different forms are hard to define, and potassium plays a different role in each one. New genetic probes should finally resolve these issues. In the meantime, attacks can be prevented in at least some patients. A multicenter study is now under way to determine the best treatment for each subtype.
Griggs
R C
RC
Department of Neurology, University of Rochester (N.Y.) School of Medicine.
Ptácek
L J
LJ
D002257:Carbonic Anhydrase Inhibitors / Q000627:therapeutic use; D006801:Humans; D010245:Paralyses, Familial Periodic / Q000145:classification / Q000188:drug therapy / Q000503:physiopathology; D015222:Sodium Channels / Q000235:genetics
D002257:Carbonic Anhydrase Inhibitors; D015222:Sodium Channels