title: [An immunoenzyme test (ELISA) for the detection of circulating class-IgA antibodies in human leptospirosis].
abstract: An enzyme-linked immunosorbent assay ELISA was evaluated for the detection of IgA antibodies in the human leptospirosis. The assay proved to be sensitive and specific when compared with the ELISA-IgM, in the examined serum samples. The results found suggest that IgA antibodies became positive later in leptospirosis, and will can be an evolutive indicator in the development of the disease.
authors.affiliation: Seçáo de Sorologia, Instituto Adolfo Lutz, Secretaria de Saúde do Estado de Sáo Paulo, Brasil.
authors.forename: M V
authors.initials: MV
authors.lastname: da Silva
authors.forename: E D
authors.initials: ED
authors.lastname: Camargo
mesh_terms: D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D016009:Chi-Square Distribution; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood; D007921:Leptospira interrogans / Q000276:immunology*; D041341:Leptospira interrogans serovar canicola / Q000276:immunology*; D007922:Leptospirosis / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D014895:Weil Disease / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D015415:Biomarkers; D007070:Immunoglobulin A; D007075:Immunoglobulin M
vernacular_title: Teste imunoenzimático (ELISA) para detecção de anticorpos circulantes da classe IgA na leptospirose humana.