Radiation therapy, an important mode of treatment for head and neck chemodectomas.
Between 1970 and 1990, 22 patients with 44 chemodectomas in the head and neck region were seen at the Netherlands Cancer Institute in Amsterdam. All patients were treated with radiation therapy (17 patients with radiation therapy only and 5 in combination with surgery). One patient was treated two times with an interval of 12 years at each side of the neck. Standard dose was 50 Gy in 25 fractions over 5 weeks. A radiation portal arrangement with oblique fields with paired wedges was used most frequently. The follow-up period ranged from 1 year to 20 years. Two recurrences at 2 and 9 years after treatment were observed. The actuarial local control rate was 88% at 10 years follow-up. Comparison of the results of surgery and radiotherapy demonstrates that radiation therapy is an effective treatment modality without mutilation or severe late morbidity for chemodectomas in the head and neck region.
Verniers
D A
DA
Dr. Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands.
Keus
R B
RB
Schouwenburg
P F
PF
Bartelink
H
H
D000328:Adult; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D009364:Neoplasm Recurrence, Local; D010236:Paraganglioma, Extra-Adrenal / Q000532:radiotherapy* / Q000601:surgery; D016896:Treatment Outcome