title: [The status of and causes of change in the immunological reactivity of patients with iron-deficiency anemia].
abstract: The role of the immunity system in the pathogenesis of iron deficiency anemia and its complications was studied in 200 patients and in the experiment on 55 non-inbred white rats. The state of nonspecific resistance, humoral and cellular components of immunity was investigated. It has been shown that iron deficiency leads to imbalance in the immunity system. The degree of the affection and disorders in the integration between separate parameters of the immunity system determine the possibility of complications and influence the course of concomitant diseases. Ferrotherapy produces a positive effect on the immune status of patients with iron deficiency anemia.
authors.forename: A A
authors.initials: AA
authors.lastname: Golovin
authors.forename: T F
authors.initials: TF
authors.lastname: Sokolova
mesh_terms: D000293:Adolescent; D000328:Adult; D000747:Anemia, Hypochromic / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D000937:Antigen-Antibody Reactions / Q000187:drug effects / Q000276:immunology*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007113:Immunity, Innate / Q000187:drug effects; D007501:Iron / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D051381:Rats
chemical_list: D007501:Iron
vernacular_title: Sostoianie i prichiny izmeneniia immunologicheskoĭ reaktivnosti u bol'nykh zhelezodefitsitnoĭ anemieĭ.