[Opportunistic toxoplasmosis in a case of heart transplantation].
Infection with toxoplasma gondii is a serious complication in the immunocompromised heart transplant recipient. We reported a case of toxoplasmosis in a seronegative heart transplant recipient detected on endomyocardial biopsy. This patient was treated with oral pyrimethamine and sulphadiazine. Because primary toxoplasmosis occurred in seronegative patients receiving hearts from sero-positive donors, it is necessary to screen both recipients and donors for T. gondii. Prophylaxis with pyrimethamine in sero-negative patients transplanted with a heart from sero-positive donors confers considerable benefit.
Albat
B
B
Service de Chirurgie Thoracique et Cardio Vasculaire CHR Aiguelongue, Montpellier.
Serre
I
I
Pratlong
F
F
Thevenet
A
A
Baldet
P
P
D000328:Adult; D006084:Graft Rejection; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008297:Male; D009894:Opportunistic Infections / Q000150:complications*; D014123:Toxoplasmosis / Q000150:complications* / Q000635:transmission
Toxoplasmose opportuniste chez un transplanté cardiaque.