title: Intraepithelial neoplasia of the lower female genital tract: etiology, investigation, and management.
abstract: Lower genital tract neoplasia appears associated with certain types of the human papilloma virus. Surgical approaches using lasers and electricity are available to treat the clinical diseases and in turn provide good cosmetic and functional anatomy. The surgical method employed depends upon the anatomical and histological distribution of disease regardless of its site. Of the three areas (cervix, vagina and vulva), cervical intraepithelial neoplasia is the least difficult to cure. Vulvar intraepithelial neoplasia is the most difficult since recurrences can occur at any time and in some patients for many years.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Western Ontario, London, Canada.
authors.forename: V C
authors.initials: VC
authors.lastname: Wright
authors.forename: W
authors.initials: W
authors.lastname: Chapman
mesh_terms: D002278:Carcinoma in Situ / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery; D003131:Combined Modality Therapy; D004598:Electrosurgery; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D005833:Genital Neoplasms, Female / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery; D006801:Humans; D053685:Laser Therapy; D027383:Papillomaviridae / Q000302:isolation & purification; D014412:Tumor Virus Infections / Q000175:diagnosis
chemical_list: D005472:Fluorouracil