title: Circulating concentrations of fetal fibronectin do not reflect reduced trophoblastic invasion in preeclamptic pregnancies.
abstract: This prospective, nested, case-control study investigated whether maternal plasma fetal fibronectin reflects reduced trophoblastic invasion at 16 to 20 weeks in women who later have preeclampsia. Concentrations of fetal fibronectin were 8.7 +/- 2.6 micrograms/ml in women with preeclampsia and 8.1 +/- 2.5 micrograms/ml in matched controls (p greater than 0.5). These results are discussed.
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco.
authors.forename: S A
authors.initials: SA
authors.lastname: Friedman
authors.forename: C J
authors.initials: CJ
authors.lastname: de Groot
authors.forename: R N
authors.initials: RN
authors.lastname: Taylor
authors.forename: J M
authors.initials: JM
authors.lastname: Roberts
mesh_terms: D016022:Case-Control Studies; D005260:Female; D005312:Fetal Blood; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D009361:Neoplasm Invasiveness; D009994:Osmolar Concentration; D011225:Pre-Eclampsia / Q000150:complications*; D011247:Pregnancy; D011446:Prospective Studies; D012016:Reference Values; D014328:Trophoblastic Neoplasms / Q000150:complications / Q000473:pathology*
chemical_list: D005353:Fibronectins