title: Scaffold-associated regions: cis-acting determinants of chromatin structural loops and functional domains.
abstract: It has been proposed that scaffold-associated regions are DNA elements that form the bases of chromatin loops in eukaryotic cells. Recent evidence supports a role for these elements as cis-acting 'handlers' of both structural and functional chromatin domains.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Geneva, Switzerland.
authors.forename: U K
authors.initials: UK
authors.lastname: Laemmli
authors.forename: E
authors.initials: E
authors.lastname: Käs
authors.forename: L
authors.initials: L
authors.lastname: Poljak
authors.forename: Y
authors.initials: Y
authors.lastname: Adachi
mesh_terms: D000818:Animals; D001483:Base Sequence; D002843:Chromatin / Q000737:chemistry* / Q000502:physiology*; D004250:DNA Topoisomerases, Type II / Q000502:physiology; D004268:DNA-Binding Proteins / Q000502:physiology; D008938:Mitosis / Q000502:physiology; D008969:Molecular Sequence Data
chemical_list: D002843:Chromatin; D004268:DNA-Binding Proteins; D004250:DNA Topoisomerases, Type II