title: [Hepatic fibrosis and its serum markers].
abstract: As serum markers for hepatitis fibrosis, prolyl hydroxylase (PH), type III procollagen peptide (PIIIP), type IV collagen, mesenchymal metalloproteinase (MMP), tissue inhibitor of metalloproteinase (TIMP) and laminin are reliable for clinical application. PH, PIIIP, MMP, TIMP and LM are regarded as the marker of ongoing hepatic fibrosis. Type IV collagen and LM are indicative for the extent of hepatic fibrosis.
authors.affiliation: Department of Medicine, St. Marianna University School of Medicine, Yokohama Seibu Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Okabe
mesh_terms: D015415:Biomarkers / Q000032:analysis*; D003094:Collagen / Q000097:blood; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood; D011347:Procollagen / Q000097:blood; D011393:Procollagen-Proline Dioxygenase / Q000097:blood
chemical_list: D015415:Biomarkers; D010446:Peptide Fragments; D011347:Procollagen; C041876:procollagen Type III-N-terminal peptide; D003094:Collagen; D011393:Procollagen-Proline Dioxygenase; C030606:proline, 2-oxoglutarate 3-dioxygenase