title: Technetium 99m pentavalent dimercaptosuccinic acid and thallium 201 in detecting recurrent medullary carcinoma of the thyroid.
abstract: To compare the effectiveness of thallium chloride 201 and technetium 99m pentavalent dimercaptosuccinic acid in evaluating medullary carcinoma of the thyroid (MCT), eight patients with a history of MCT underwent imaging with both radiopharmaceuticals. Thallium 201 consistently gave superior images, as well as providing one less false-negative scan. Positive scans were obtained in patients with elevation of basal calcitonin levels to more than 1,000 ng/L. All of the patients with positive scans had clinical evidence of local recurrence. Improved imaging with thallium 201 was obtained by early scanning.
authors.affiliation: Department of General Surgery, University of Saskatchewan, Saskatoon.
authors.forename: R J
authors.initials: RJ
authors.lastname: Bigsby
authors.forename: E K
authors.initials: EK
authors.lastname: Lepp
authors.forename: D E
authors.initials: DE
authors.lastname: Litwin
authors.forename: A A
authors.initials: AA
authors.lastname: Wilkinson
authors.forename: G G
authors.initials: GG
authors.lastname: Matte
mesh_terms: D002116:Calcitonin / Q000097:blood; D002277:Carcinoma / Q000097:blood / Q000000981:diagnostic imaging*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000097:blood / Q000000981:diagnostic imaging*; D015609:Organotechnetium Compounds; D012680:Sensitivity and Specificity; D004113:Succimer; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D013794:Thallium Radioisotopes; D013964:Thyroid Neoplasms / Q000097:blood / Q000000981:diagnostic imaging*; D014055:Tomography, Emission-Computed; D014915:Whole-Body Counting / Q000295:instrumentation
chemical_list: D015609:Organotechnetium Compounds; D013794:Thallium Radioisotopes; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D002116:Calcitonin; D004113:Succimer