Ultrastructural changes in the parotid serous cells of white male rats after experimental encortone.
Mature male rats received encortone in a dose of 1 mg/kg of body mass for 7 days and 30 days. The following changes were observed in the cells of parotid gland of the experimental animals in comparison with the control: a) after 7 days of encortone treatment increase of secretory cells activity appeared in the intensive production and secretion, b) after 30 days of encortone treatment a decrease in secretion production. Moreover, hyperplasia of serous cells, hyperthropy of cell nuclei, pycnosis of nuclei in some serous cells and hyperplasia of epithelium in some intercalated ducts were observed.
Zarebska
A
A
Department of Histology and Embryology, Medical Academy, Lublin.
Królikowska-Prasał
I
I
D000818:Animals; D008297:Male; D010306:Parotid Gland / Q000187:drug effects / Q000648:ultrastructure*; D011241:Prednisone / Q000494:pharmacology / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar
D011241:Prednisone