[The presence of the Epstein-Barr virus in Waldeyer's lymphatic ring during the acute phase of infectious mononucleosis].
The aim of our research was to detect the existence of virus Epstein-Barr genome in the palatine- and the nasopharyngeal tonsil obtained from six patients during the acute phase of the infectious mononucleosis. The presence of EBV-DNA was demonstrated with the help of nucleic acid hybridization techniques (Southern-Blot and in situ hybridization) in the two components of the lymphoepithelial ring of the throat. The pathogenesis and the therapeutic implications of these findings are discussed.
Bujía
J
J
Cátedra de Otorrinolaringología, Ludwig-Maximilians-Universität München.
Wilmes
E
E
Wolf
H
H
Bartual
J
J
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D015139:Blotting, Southern; D002648:Child; D002675:Child, Preschool; D004279:DNA, Viral / Q000235:genetics; D016679:Genome, Viral; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007244:Infectious Mononucleosis / Q000382:microbiology*; D009693:Nucleic Acid Hybridization; D014066:Palatine Tonsil / Q000382:microbiology*
D004279:DNA, Viral
Presencia del virus de Epstein-Barr en el anillo linfático de Waldeyer durante la fase aguda de la mononucleosis infecciosa.