Effect of diets containing different levels of calcium, phosphate, and vitamin D3 on tooth uptake of 47Ca-chloride in rat models: comparison with bone uptake.
The effect of dietary manipulation on global tooth uptake of 47Ca-chloride was evaluated in three rat models of metabolic bone diseases verified by histologic bone study. The 24-hr tooth uptake of 47Ca-chloride was significantly decreased in the osteomalacic group, and was increased in the osteoporotic group at the fourth week. Tooth uptake closely paralleled femoral uptake at a correlation coefficient of 0.73 (p less than 0.01). The uptake of 47Ca-chloride in tooth was found to be more affected by dietary manipulation than that in femur in our rat models.
Seto
H
H
Department of Radiological Sciences, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
Ihara
F
F
Shimizu
M
M
Kageyama
M
M
Futatsuya
R
R
Kakishita
M
M
D000818:Animals; D002118:Calcium / Q000097:blood; D002122:Calcium Chloride / Q000378:metabolism*; D002132:Calcium Radioisotopes; D002136:Calcium, Dietary / Q000008:administration & dosage / Q000494:pharmacology*; D002762:Cholecalciferol / Q000008:administration & dosage / Q000494:pharmacology*; D005269:Femur / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D008297:Male; D010018:Osteomalacia / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D010024:Osteoporosis / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D010281:Parathyroid Hormone / Q000097:blood; D010710:Phosphates / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D011877:Radionuclide Imaging; D051381:Rats; D017208:Rats, Wistar; D014070:Tooth / Q000000981:diagnostic imaging / Q000378:metabolism*
D002132:Calcium Radioisotopes; D002136:Calcium, Dietary; D010281:Parathyroid Hormone; D010710:Phosphates; D002762:Cholecalciferol; D002122:Calcium Chloride; D002118:Calcium