title: Comparison of Indium-111-labeled leukocyte scintigraphy and Technetium-99m joint scintigraphy in rheumatoid arthritis and osteoarthritis.
abstract: This study was undertaken to evaluate the use of Indium-111-labeled leukocyte (111In-WBC) imaging compared with Technetium-99m pertechnetate (99mTcO4-) imaging in 19 patients with rheumatoid arthritis (RA) and 8 with osteoarthritis. Knee and wrist joints were evaluated for both radionuclides. The results indicated a good correlation of the clinical assessment of pain and swelling with joint uptake ratio (JUR) between 111In-WBC and 99mTcO4- in RA and osteoarthritis patients. We observed a discrepancy in both imagings in "burned out" cases. It was concluded that a JUR of 111In-WBC could distinguish active RA from inactive RA or osteoarthritis at a value of 1.15 and that the use of 111In-WBC was a more reliable procedure than 99mTcO4-.
authors.affiliation: Department of Radiology, Chiba University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Uno
authors.forename: T
authors.initials: T
authors.lastname: Suguro
authors.forename: K
authors.initials: K
authors.lastname: Nohira
authors.forename: H
authors.initials: H
authors.lastname: Moriya
authors.forename: K
authors.initials: K
authors.lastname: Saegusa
authors.forename: Y
authors.initials: Y
authors.lastname: Anzai
authors.forename: T
authors.initials: T
authors.lastname: Terauchi
authors.forename: K
authors.initials: K
authors.lastname: Sato
authors.forename: S
authors.initials: S
authors.lastname: Uematsu
authors.forename: N
authors.initials: N
authors.lastname: Arimizu
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D007719:Knee Joint / Q000000981:diagnostic imaging; D007962:Leukocytes; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D013670:Sodium Pertechnetate Tc 99m; D014955:Wrist Joint / Q000000981:diagnostic imaging
chemical_list: D007205:Indium Radioisotopes; D013670:Sodium Pertechnetate Tc 99m