title: Longitudinal monitoring for disease progression of localized juvenile periodontitis.
abstract: The present study was performed to investigate the factors associated with disease progression in localized juvenile periodontitis (LJP) patients by longitudinal monitoring of microbiological changes. Following a 9-month period, 9 LJP patients were divided into 2 groups based upon attachment loss, progressing and non-progressing. Both groups received scaling, root planing, and modified Widman flaps. Clinical and microbiological data were obtained at baseline, following the observation period, and at 6 and 12 months post-treatment. At 6 and 12 months post-treatment significantly more cocci were persistent in the non-progressing group than in the progressing group. Actinobacillus actinomycetemcomitans was also more frequently isolated in the progressing group than in the non-progressing group initially and following the 9-month observation period. Also after treatment, A. actinomycetemcomitans recolonized earlier in the progressing group than in the non-progressing group. These studies suggest that A. actinomycetemcomitans may play a role in disease progression in LJP; however, they do not eliminate the possibility that other organisms may also play a role, since A. actinomycetemcomitans was not detected in all of the patients in whom disease progressed.
authors.affiliation: Department of Periodontology, College of Dentistry, Seoul National University, Korea.
authors.forename: K J
authors.initials: KJ
authors.lastname: Kim
authors.forename: D K
authors.initials: DK
authors.lastname: Kim
authors.forename: C P
authors.initials: CP
authors.lastname: Chung
authors.forename: S
authors.initials: S
authors.lastname: Son
mesh_terms: D000293:Adolescent; D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification; D010520:Aggressive Periodontitis / Q000382:microbiology* / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D001419:Bacteria / Q000145:classification / Q000302:isolation & purification*; D001439:Bacteroides / Q000302:isolation & purification; D015169:Colony Count, Microbial; D003774:Dental Plaque Index; D005260:Female; D005884:Gingival Hemorrhage / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000382:microbiology / Q000473:pathology; D016966:Porphyromonas gingivalis / Q000302:isolation & purification