Inhibition of myo-inositol 1-phosphatase by cis-1,2,3-cyclohexanetriol 1-phosphate, a molecular simplification of the natural substrate.
Harrold
M W
MW
Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282.
Sriburi
A
A
Caimano
P
P
Qi
H
H
Seybert
D
D
Lin
F T
FT
D000818:Animals; D001921:Brain / Q000201:enzymology; D002417:Cattle; D003511:Cyclohexanols / Q000138:chemical synthesis* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D010744:Phosphoric Monoester Hydrolases / Q000037:antagonists & inhibitors*
D003511:Cyclohexanols; D009943:Organophosphorus Compounds; C078321:1,2,3-cyclohexanetriol-1-phosphate; D010744:Phosphoric Monoester Hydrolases; C021822:myo-inositol-1 (or 4)-monophosphatase