Determination of naphazoline in rat plasma using column liquid chromatography with ultraviolet detection.
A sensitive (1 ng/mL) and rapid method for the determination of naphazoline in rat plasma is described. Following extraction, the compound is analysed by reversed phase high performance liquid chromatography and ultraviolet detection at 214 nm.
Chabenat
C
C
Laboratoire de Pharmacochimie, UFR de Médecine et Pharmacie de Rouen, Rouvray, France.
Boucly
P
P
D000818:Animals; D011232:Chemical Precipitation; D002851:Chromatography, High Pressure Liquid / Q000379:methods* / Q000592:standards / Q000706:statistics & numerical data; D006863:Hydrogen-Ion Concentration; D008297:Male; D008832:Microchemistry; D009278:Naphazoline / Q000097:blood*; D010472:Perchlorates; D011786:Quality Control; D051381:Rats; D017207:Rats, Sprague-Dawley; D012997:Solvents
D010472:Perchlorates; D012997:Solvents; D009278:Naphazoline