[The neurotropic and cardiotropic properties of new amino acid derivatives of isonicotinic acid].
Different derivatives of isonicotinic acid are used widely enough as antimicrobial and antituberculous agents. However, their neurotropic and cardiotropic effects have been studied little. The paper is concerned with investigations of these types of the activity of the new derivatives of isonicotinic acid: beta-phenyl-beta-alanine, l-proline, DL-valine, beta-alanine and DL-threonine synthesized for the first time at the Institute of Fine Organic Chemistry, Academy of Sciences of Armenia.
Samvelian
V M
VM
Kazarian
S A
SA
Matevosian
L A
LA
Dzhanpoladian
E G
EG
Khoetsian
E L
EL
Mndzhoian
O L
OL
D000787:Angina Pectoris / Q000188:drug therapy; D000818:Animals; D002317:Cardiovascular Agents / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D002415:Cats; D004353:Drug Evaluation, Preclinical; D005260:Female; D006321:Heart / Q000187:drug effects; D066298:In Vitro Techniques; D007539:Isonicotinic Acids / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D009420:Nervous System / Q000187:drug effects*; D011898:Ranidae; D051381:Rats; D011956:Receptors, Cell Surface / Q000187:drug effects; D012890:Sleep / Q000187:drug effects
D002317:Cardiovascular Agents; D007539:Isonicotinic Acids; D011956:Receptors, Cell Surface
Neĭrotropnye i kardiotropnye svoĭstva nekotorykh novykh aminokislotnykh proizvodnykh izonikotinovoĭ kisloty.