title: [In vivo chemosensitivity of Plasmodium falciparum to chloroquine in Burkina Faso: development of resistance 1988-1990].
abstract: A study of Plasmodium falciparum sensitivity to chloroquine was carried out in 1988 and 1990 in 5 localities, representatives of different climatic areas of Burkina Faso. The 7-day in vivo standard test performed in 1988 showed a total clearance failure of 25%. No significant difference with 1990 data was found, except for an increase of the resistance in the area of Fada N'Gourma, close to the border with Benin, Niger and Togo.
authors.affiliation: Centre de Lutte contre le Paludisme, Ouagadougou, Burkina Faso.
authors.forename: V
authors.initials: V
authors.lastname: Pietra
authors.forename: L
authors.initials: L
authors.lastname: Lamizana
authors.forename: L
authors.initials: L
authors.lastname: del Nero
authors.forename: G
authors.initials: G
authors.lastname: Rotigliano
mesh_terms: D000818:Animals; D002050:Burkina Faso / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D002738:Chloroquine / Q000494:pharmacology* / Q000627:therapeutic use; D004351:Drug Resistance; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy / Q000453:epidemiology; D010963:Plasmodium falciparum / Q000187:drug effects*
chemical_list: D002738:Chloroquine
vernacular_title: Surveillance de la chimiosensibilite in vivo de Plasmodium falciparum a la chloroquine au Burkina Faso: evolution de la resistance 1988-1990.