Molecular evidence linking hominid evolution to recent radiation of schistosomes (Platyhelminthes: Trematoda).
Molecular phylogenies for seven species of schistosomes, including four species infecting man, were constructed from PCR-amplified sequences of two ribosomal genes: one nuclear (internal transcribed spacer 2 in the ribosomal multigenic family) and one mitochondrial (16S rDNA). The two phylogenies obtained are congruent, and the data suggest that the mitochondrial sequence evolves about three times faster than the nuclear sequence. We propose a calibration of the phylogenetic tree of schistosomes that dates "human capture" of these parasites from other animal hosts (rodents and ruminants) in Africa to 1-10 million years ago, when the first hominids invaded savanna areas, which are the favorable environment for parasite transmission.
Despres
L
L
URA CNRS 1493, Laboratoire Génome et Populations, Université Montpellier II, France.
Imbert-Establet
D
D
Combes
C
C
Bonhomme
F
F
D000349:Africa; D000818:Animals; D001208:Asia; D001483:Base Sequence; D005075:Biological Evolution; D004272:DNA, Mitochondrial / Q000235:genetics; D004275:DNA, Ribosomal / Q000235:genetics; D015186:Hominidae / Q000145:classification / Q000235:genetics* / Q000469:parasitology; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012547:Schistosoma / Q000033:anatomy & histology / Q000145:classification* / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
D004272:DNA, Mitochondrial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S