title: High-affinity kainate and domoate receptors in rat brain.
abstract: Mammalian brain expresses receptors which bind the potent neurotoxins, kainate and domoate, with high affinity, and which form a subclass of ionotropic glutamate receptors. A new member of these receptors, expressed in both adult and embryonic CNS is compared in its ligand binding properties to its closely sequence-related homologs.
authors.affiliation: Laboratory of Molecular Neuroendocrinology, Heidelberg University, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Lomeli
authors.forename: W
authors.initials: W
authors.lastname: Wisden
authors.forename: M
authors.initials: M
authors.lastname: Köhler
authors.forename: K
authors.initials: K
authors.lastname: Keinänen
authors.forename: B
authors.initials: B
authors.lastname: Sommer
authors.forename: P H
authors.initials: PH
authors.lastname: Seeburg
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001921:Brain / Q000378:metabolism*; D004247:DNA; D005971:Glutamates / Q000378:metabolism; D007608:Kainic Acid / Q000031:analogs & derivatives* / Q000378:metabolism*; D008969:Molecular Sequence Data; D051381:Rats; D017470:Receptors, Glutamate; D018092:Kainic Acid Receptors; D017981:Receptors, Neurotransmitter / Q000737:chemistry / Q000378:metabolism*; D016415:Sequence Alignment
chemical_list: D004247:DNA; D005971:Glutamates; D007608:Kainic Acid; D017470:Receptors, Glutamate; D018092:Kainic Acid Receptors; D017981:Receptors, Neurotransmitter; C012301:domoic acid