title: [The use of acetylsalicylic acid as a platelet antiaggregant].
abstract: OBJECTIVE
  To comprove the efficiency of acetyl salicylic acid (ASA) as platelet antiaggregant drug, a 100 mg/day dose base.
  
  
  METHODS
  Two hundred and fifty-eight patients were studied between 1988 and 1990. Platelet functions were measured using an aggregometer plus ADP 5 as platelet aggregation inductor.
  
  
  RESULTS
  Two groups were studied: 1st group, using ASA (111 patients), 91 hypoaggregants; 2nd group, not using ASA (147 patients), 120 normals, 12 hypoaggregants and 15 hyperaggregants. From the 2nd group, 91 had another evaluation under the use of ASA and showed a clear effect of the drug.
  
  
  CONCLUSIONS
  The use of aspirin, 100 mg/day dose, is enough to reduce platelet antiaggregation.
authors.affiliation: Fundação de Hematologia e Hemoterapia de PE, Hospital das Clínicas, UFPE.
authors.forename: A R
authors.initials: AR
authors.lastname: de Araújo
authors.forename: M I
authors.initials: MI
authors.lastname: Sobreira
authors.forename: G O
authors.initials: GO
authors.lastname: de Melo
authors.forename: C M
authors.initials: CM
authors.lastname: Mendonca
authors.forename: E A
authors.initials: EA
authors.lastname: Maranhão
authors.forename: M S
authors.initials: MS
authors.lastname: Leite
authors.forename: F L
authors.initials: FL
authors.lastname: Santos
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001241:Aspirin / Q000008:administration & dosage*; D002648:Child; D004341:Drug Evaluation; D006331:Heart Diseases / Q000097:blood / Q000188:drug therapy; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects
chemical_list: D001241:Aspirin
vernacular_title: Uso do acido acetil salicílico como antiagregante plaquetário.