title: Restoration of the lateral sinus wall using a collagen type I membrane for guided tissue regeneration.
abstract: A collagen type I membrane prepared from bovine pericard was used to restore and thicken the lateral sinus wall after resection in 6 Göttingen minipigs. One rehydrated collagen type I membrane was placed on the intact sinus mucosa. A hydroxyapatite block was placed on this membrane and covered with a second membrane. After 6 months there was complete, bony regeneration in the space between the 2 membranes and thickening of the new bone plate compared to the untreated control side. This study shows that a collagen membrane can be applied for guided tissue regeneration.
authors.affiliation: Department of Oral Surgery, Faculty of Dentistry, Free University of Berlin, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Becker
authors.forename: F W
authors.initials: FW
authors.lastname: Neukam
authors.forename: H
authors.initials: H
authors.lastname: Schliephake
mesh_terms: D000818:Animals; D001861:Bone Regeneration; D016025:Bone Transplantation / Q000379:methods; D002417:Cattle; D003094:Collagen / Q000737:chemistry; D017886:Durapatite; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D006097:Granulation Tissue / Q000473:pathology; D048091:Guided Tissue Regeneration; D006882:Hydroxyapatites / Q000737:chemistry; D008443:Maxillary Sinus / Q000473:pathology / Q000601:surgery*; D008567:Membranes, Artificial; D019736:Prostheses and Implants; D013499:Surface Properties; D013552:Swine; D013556:Swine, Miniature; D014945:Wound Healing
chemical_list: D006882:Hydroxyapatites; D008567:Membranes, Artificial; D003094:Collagen; D017886:Durapatite