[Granulocyte metabolism in workers at a coke-processing plant].
Acid phosphatase activity examinations and nitrotetrazolium blue reduction test after latex stimulation in peripheral blood neutrophils were performed in the group of 32 coking plant workers. Reference group consisted of 150 men not exposed to any toxic substances. Neutrophils of coking plant workers, comparing with the reference group, revealed decreased activity of acid phosphatase and impaired reduction of nitrotetrazolium blue after latex stimulation. The results suggest the possibility of toxic influence of coking plant environment on the lysosomal enzymes and oxygen-dependent metabolism of neutrophils what subsequently may diminish bactericidal powers.
Misiewicz
A
A
VI Katedry i Kliniki Chorób Wewnetrznych Sl. AM, Katowicach.
Trzcionka-Bera
D
D
Stoch
K
K
D000135:Acid Phosphatase / Q000037:antagonists & inhibitors / Q000097:blood*; D000328:Adult; D000395:Air Pollutants, Occupational / Q000633:toxicity*; D001554:Benzene / Q000633:toxicity*; D002617:Chemical Industry; D003077:Coke; D006801:Humans; D006856:Hydrogen Cyanide / Q000633:toxicity*; D007841:Latex Fixation Tests / Q000379:methods; D008297:Male; D009504:Neutrophils / Q000187:drug effects / Q000201:enzymology*; D009580:Nitroblue Tetrazolium; D009585:Nitrogen Dioxide / Q000633:toxicity*; D011044:Poland
D000395:Air Pollutants, Occupational; D003077:Coke; D009580:Nitroblue Tetrazolium; D006856:Hydrogen Cyanide; D000135:Acid Phosphatase; D001554:Benzene; D009585:Nitrogen Dioxide
Metabolizm granulocytów pracowników koksowni.