[Cushing syndrome in a neuroendocrine pancreatic tumor. Clinicopathologic case report].
A 59-year-old female patient with mild clinical features of a Cushing syndrome underwent surgery for a suspected hormonally active tumor of the left adrenal gland. Surprisingly, the adrenal gland was unremarkable, however, a tumor in the pancreatic tail was found. A left pancreatic resection with splenectomy resulted in curative removal of the tumor. The pathohistological examination of the tumor established the diagnosis of an ACTH-producing pancreatic carcinoid. Morphology and pathogenesis of pancreatic carcinoids which are tumors of the APUD-cell-system are discussed in detail.
Schneider
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Zentrum für Chirurgie, Städtischen Klinikums Nürnberg.
Mittelmeier
H O
HO
Gebhardt
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C
D000182:ACTH Syndrome, Ectopic / Q000473:pathology* / Q000601:surgery; D000324:Adrenocorticotropic Hormone / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D002276:Carcinoid Tumor / Q000473:pathology* / Q000601:surgery; D003480:Cushing Syndrome / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery
D014408:Biomarkers, Tumor; D000324:Adrenocorticotropic Hormone
Cushing-Syndrom bei einem neuroendokrinen Pankreastumor. Klinisch-pathologischer Fallbericht.