Randomized double-blinded comparison of three intravenous immunoglobulin products in bone marrow transplantation.
We have used samples from the in vivo situation to compare antibody levels provided by the infusion of different IVIG products, a measure, albeit indirect, of potential therapeutic efficacy. The further correlation of in vivo antibody titers with functional activities of these antibodies (eg, opsonization and viral neutralization) would provide additive valuable information about the usefulness of this therapy.
Peltier
M K
MK
Pharmacy Department, University of Minnesota Hospital and Clinic, Minneapolis 55455.
Filipovich
A H
AH
Bechtel
M
M
Dirksen
C L
CL
Englund
J A
JA
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D016026:Bone Marrow Transplantation / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000276:immunology / Q000517:prevention & control*; D004311:Double-Blind Method; D006801:Humans; D007116:Immunization, Passive; D007074:Immunoglobulin G / Q000032:analysis; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007223:Infant; D014777:Virus Diseases / Q000276:immunology / Q000517:prevention & control
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D016756:Immunoglobulins, Intravenous