The activation of cAMP-dependent protein kinase is directly linked to homologous desensitization by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic osteosarcoma cells.
Sugimoto
T
T
Department of Medicine, Kobe University School of Medicine, Japan.
Kano
J
J
Fukase
M
M
Fujita
T
T
D001859:Bone Neoplasms / Q000201:enzymology*; D000242:Cyclic AMP / Q000494:pharmacology; D006801:Humans; D012516:Osteosarcoma / Q000201:enzymology*; D010281:Parathyroid Hormone / Q000494:pharmacology*; D044162:Parathyroid Hormone-Related Protein; D010446:Peptide Fragments / Q000494:pharmacology*; D011494:Protein Kinases / Q000378:metabolism*; D011506:Proteins / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D010281:Parathyroid Hormone; D044162:Parathyroid Hormone-Related Protein; D010446:Peptide Fragments; D011506:Proteins; C054296:parathyroid hormone-related protein (1-34); D000242:Cyclic AMP; D011494:Protein Kinases