[An immunoenzyme test (ELISA) for the detection of circulating class-IgA antibodies in human leptospirosis].
An enzyme-linked immunosorbent assay ELISA was evaluated for the detection of IgA antibodies in the human leptospirosis. The assay proved to be sensitive and specific when compared with the ELISA-IgM, in the examined serum samples. The results found suggest that IgA antibodies became positive later in leptospirosis, and will can be an evolutive indicator in the development of the disease.
da Silva
M V
MV
Seçáo de Sorologia, Instituto Adolfo Lutz, Secretaria de Saúde do Estado de Sáo Paulo, Brasil.
Camargo
E D
ED
D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D016009:Chi-Square Distribution; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood; D007921:Leptospira interrogans / Q000276:immunology*; D041341:Leptospira interrogans serovar canicola / Q000276:immunology*; D007922:Leptospirosis / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D014895:Weil Disease / Q000276:immunology*
D000907:Antibodies, Bacterial; D015415:Biomarkers; D007070:Immunoglobulin A; D007075:Immunoglobulin M
Teste imunoenzimático (ELISA) para detecção de anticorpos circulantes da classe IgA na leptospirose humana.