title: Prognostic significance of computed tomography in resected N2 lung cancer.
abstract: We reviewed 124 patients from 1982 to 1988 who had a resected primary non-small cell lung cancer metastatic to mediastinal (N2) lymph nodes and a preoperative assessment of the mediastinum with computed tomography of the chest. Sixty-three patients studied had computed tomographic evidence of mediastinal lymph node enlargement. In these patients the survival at 5 years was only 6.6%, compared with the 5-year survival of 13.5% in 61 patients in whom the mediastinum was normal. Plain chest roentgenography with evidence of mediastinal adenopathy did not predict a poorer outcome. In addition, patients with tumors located in the left upper lobe were found to have an improved survival. These patients had a 5-year survival of 20.8%. Tumor histology, central location of the tumor, extranodal extension, and type of resection did not result in a significant survival difference.
authors.affiliation: Department of Thoracic Surgery, University of Texas M.D. Anderson Cancer Center, Houston 77030.
authors.forename: I J
authors.initials: IJ
authors.lastname: Cybulsky
authors.forename: L A
authors.initials: LA
authors.lastname: Lanza
authors.forename: M B
authors.initials: MB
authors.lastname: Ryan
authors.forename: J B
authors.initials: JB
authors.lastname: Putnam
authors.forename: M M
authors.initials: MM
authors.lastname: McMurtrey
authors.forename: J A
authors.initials: JA
authors.lastname: Roth
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging / Q000401:mortality / Q000556:secondary* / Q000601:surgery; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000601:surgery*; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008297:Male; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008875:Middle Aged; D011379:Prognosis; D015996:Survival Rate; D014057:Tomography, X-Ray Computed