title: The structure and function of Na+ channels.
abstract: The past year has seen major advances in our understanding of voltage-gated ion channels through a powerful combination of patch-clamp and molecular biological techniques. These approaches have identified regions (in some cases single amino acid residues) that are essential for voltage-dependent activation and inactivation, lining of the pore, and regulation of channel function.
authors.affiliation: Abteilung Membranebiophysik, Max Planck Institute für Biophysikalische Chemie, Göttingen, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Stühmer
authors.forename: A B
authors.initials: AB
authors.lastname: Parekh
mesh_terms: D000818:Animals; D006801:Humans; D015640:Ion Channel Gating; D015222:Sodium Channels / Q000502:physiology*
chemical_list: D015222:Sodium Channels