title: Antibodies to hepatitis C virus in kidney transplantation.
abstract: Ninety patients on dialysis, 241 cadaveric kidney donors and 27 cadaveric kidney recipients with a follow-up of 2 years, have been investigated as for anti-HCV positivity by means of 3 tests. As for patients on dialysis and cadaveric donors, the prevalence was 32 and 4%, respectively. As for transplanted patients, it must be noted that 4 negative recipients from positive donors seroconverted, but without any change in hepatic enzymes, while in 2 or 9 anti-HCV-positive recipients, hepatic enzymes increased after transplantation. Seroconversion in patients transplanted from a negative donor was not significantly different. We conclude that, according to their experience, anti-HCV positivity in the donors is not associated with a significant risk of infection in recipients of cadaveric grafts.
authors.affiliation: Renal Unit, I.N.R.C.A., Turin, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Triolo
authors.forename: G
authors.initials: G
authors.lastname: Squiccimarro
authors.forename: M
authors.initials: M
authors.lastname: Baldi
authors.forename: M
authors.initials: M
authors.lastname: Messina
authors.forename: M
authors.initials: M
authors.lastname: Salomone
authors.forename: M C
authors.initials: MC
authors.lastname: Torazza
authors.forename: L
authors.initials: L
authors.lastname: Pratico
authors.forename: F
authors.initials: F
authors.lastname: Bonino
authors.forename: A
authors.initials: A
authors.lastname: Amoroso
authors.forename: G P
authors.initials: GP
authors.lastname: Segoloni
mesh_terms: D000328:Adult; D005260:Female; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000276:immunology / Q000635:transmission; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D014019:Tissue Donors
chemical_list: D006508:Hepatitis Antibodies