title: [Mixed myelocytic and lymphocytic acute leukemia. Case report].
abstract: A patient with acute mixed myelocytic and lymphocytic leukemia is reported. The patient showed two populations of malignant myeloid and lymphoid cells with predominance of myeloid lineage. According to the present knowledge, it is hypothesized that its origin is at a pluripotent transformed stem cell which has the capability of differentiating through myeloid and lymphoid lineages. Its maturation is arrested at certain level, thus raising two monoclonal populations simultaneously in the same patient. The treatment should be combined with drugs used in acute myeloblastic and lymphoblastic leukemia. The response to chemotherapy is generally poor.
authors.affiliation: Servicio de Medicina Hospital Naval de Talcahuano, Sección Hematología Salvador Santiago, Chile.
authors.forename: E R
authors.initials: ER
authors.lastname: Casanova
authors.forename: M E
authors.initials: ME
authors.lastname: Cabrera
authors.forename: R
authors.initials: R
authors.lastname: Klaasen
authors.forename: P
authors.initials: P
authors.lastname: Tapia
authors.forename: V
authors.initials: V
authors.lastname: Yáñez
mesh_terms: D000328:Adult; D006801:Humans; D016130:Immunophenotyping; D015456:Leukemia, Biphenotypic, Acute / Q000188:drug therapy / Q000276:immunology*; D007951:Leukemia, Myeloid / Q000188:drug therapy / Q000276:immunology*; D008297:Male
vernacular_title: Leucemia aguda mixta mieloide y linfoide. Caso clinico.