title: Synovial sarcoma. A clinicopathologic study.
abstract: Twenty-five cases of synovial sarcoma were reviewed clinically, roentgenographically, and pathologically. The histopathology of each tumor was classified as either monophasic (19 cases) or biphasic (six cases). A soft-tissue mass was seen on roentgenography in 70% of patients; calcification was present in 15% of cases. Treatment included surgery, with or without radiation and/or chemotherapy. Fifteen patients remained disease free at an average of 7.5 years, one patient had pulmonary metastasis, and nine patients have died. The critical prognostic factor was adequate surgical margins; there were no local recurrences with adequate tumor-free margins, but there was an 83% recurrence rate with inadequate treatment.
authors.affiliation: Department of Orthopaedics, University of Southern California School of Medicine, Los Angeles.
authors.forename: L R
authors.initials: LR
authors.lastname: Menendez
authors.forename: E
authors.initials: E
authors.lastname: Brien
authors.forename: W W
authors.initials: WW
authors.lastname: Brien
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011859:Radiography; D013584:Sarcoma, Synovial / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery