Histological grading of gliomas.
Usefulness of grading systems based on non-specific features (e.g. mitosis, necrosis) is unequivocal in only certain types of astrocytomas, and their efficiency remains to be seen in oligodendrogliomas and in mixed oligo-astrocytomas. The possibility of grading ependymomas is still uncertain. Accordingly, only a small proportion of gliomas which occur in children can be reliably graded. Lack of reproducibility is a severe impediment of both current conventional and kinetic methods in the prognosis of gliomas.
Daumas-Duport
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C
Service d'Anatomie Pathologique, Centre Hospitalier Sainte-Anne, Paris, France.
D000328:Adult; D001254:Astrocytoma / Q000473:pathology; D014408:Biomarkers, Tumor / Q000032:analysis; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000473:pathology*; D002455:Cell Division / Q000502:physiology; D002648:Child; D004806:Ependymoma / Q000473:pathology; D005909:Glioblastoma / Q000473:pathology; D005910:Glioma / Q000473:pathology*; D006801:Humans; D009837:Oligodendroglioma / Q000473:pathology; D011379:Prognosis
D014408:Biomarkers, Tumor