Antibacterial activity in vitro of cefpirome against clinical isolates causing sexually transmitted diseases.
The in-vitro activity of cefpirome was compared with other antibiotics against organisms causing sexually transmitted diseases (STD). The excellent activity of cefpirome against Neisseria gonorrhoeae (MIC90 1.0 mg/L), Haemophilus ducreyi (MIC90 0.5 mg/L), and Gardnerella vaginalis (MIC90 1.0 mg/L) suggests that this agent might be useful in the empirical treatment of a variety of venereal diseases.
Limbert
M
M
Hoechst AG, SBU Anti-infectives Research, Frankfurt, Germany.
Seibert
G
G
Winkler
I
I
Isert
D
D
Klesel
N
N
Markus
A
A
Schrinner
E
E
D002511:Cephalosporins / Q000494:pharmacology*; D002602:Chancroid / Q000382:microbiology; D002689:Chlamydia / Q000187:drug effects; D002690:Chlamydia Infections / Q000382:microbiology; D006194:Gardnerella vaginalis / Q000187:drug effects; D006069:Gonorrhea / Q000382:microbiology; D006191:Haemophilus ducreyi / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects; D010406:Penicillins / Q000494:pharmacology; D015363:Quinolones / Q000494:pharmacology; D015231:Sexually Transmitted Diseases, Bacterial / Q000382:microbiology*; D000097572:Cefpirome
D002511:Cephalosporins; D010406:Penicillins; D015363:Quinolones; D000097572:Cefpirome