Varicella zoster virus DNA in throat swabs of vaccinees.
Ninety throat swabs from 30 healthy children who received varicella vaccine were tested for varicella zoster virus DNA by the polymerase chain reaction. Seroconversion was observed in 27 of 30 (90%) vaccinees. The positive rates were 7.4% (2/27) at one week and 0% (0/27) at four weeks after vaccination. These rates were considerably lower than those in normal children with varicella.
Ozaki
T
T
Department of Paediatrics, Showa Hospital, Kohnan, Japan.
Miwata
H
H
Asano
Y
Y
Namazue
J
J
Yamanishi
K
K
D015139:Blotting, Southern; D019433:Chickenpox Vaccine; D002648:Child; D002675:Child, Preschool; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D014645:Herpesvirus 3, Human / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D008297:Male; D010614:Pharynx / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D014765:Viral Vaccines / Q000008:administration & dosage*
D019433:Chickenpox Vaccine; D004279:DNA, Viral; D014765:Viral Vaccines