Prevalence of antibody to Epstein-Barr virus DNase in children.
Antibodies to Epstein-Barr-virus-specific DNase in children under 15 years old from Taipei, Taiwan were determined by an enzyme neutralization test. Serum was taken as positive for the anti-DNase antibody when 1 ml of serum could neutralize > or = 2 units of the DNase activity. Among the 1,292 sera tested, 5.6% of the children were shown to have anti-EBV DNase antibodies, a result similar to that for adults. Maternal antibodies against the EBV DNase were found to decrease very rapidly 2 months after the child's birth, and new antibody appeared upon natural EBV infection.
Liu
M Y
MY
Department of Bacteriology, National Taiwan University, Taipei, Republic of China.
Cho
S M
SM
Tsai
W S
WS
Chang
M H
MH
Chen
J Y
JY
Yang
C S
CS
D000293:Adolescent; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D003851:Deoxyribonucleases / Q000276:immunology*; D005260:Female; D004854:Herpesvirus 4, Human / Q000201:enzymology / Q000276:immunology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009500:Neutralization Tests; D015995:Prevalence; D013624:Taiwan / Q000453:epidemiology; D014412:Tumor Virus Infections / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology*
D000914:Antibodies, Viral; D003851:Deoxyribonucleases