title: [Localization of Na/K ATP-ase in the inner ear].
abstract: The perilymphatic compartment of the inner ear resembles plasma ultrafiltrate, whereas the endolymphatic compartment is characterized by a high potassium and low sodium concentration. Perilymph is considered to be the precursor of endolymph. The chemical composition of endolymph and the generation of the transepithelial potential is regulated by Na-K-activated adenosine triphosphatase. The cytochemical localization of Na/K ATP-ase is demonstrated in the guinea pig inner ear. The mechanism for cation regulation in the endolymphatic compartment is discussed.
authors.affiliation: Afdeling KNO, Universitair Ziekenhuis Gent, België.
authors.forename: F W
authors.initials: FW
authors.lastname: Albers
authors.forename: P P
authors.initials: PP
authors.lastname: van Benthem
authors.forename: J C
authors.initials: JC
authors.lastname: de Groot
mesh_terms: D000818:Animals; D003051:Cochlea / Q000201:enzymology; D007758:Ear, Inner / Q000201:enzymology*; D004710:Endolymph / Q000201:enzymology; D004712:Endolymphatic Sac / Q000201:enzymology; D006168:Guinea Pigs; D010498:Perilymph / Q000201:enzymology; D000254:Sodium-Potassium-Exchanging ATPase / Q000032:analysis*
chemical_list: D000254:Sodium-Potassium-Exchanging ATPase
vernacular_title: De lokalisatie van Na/K ATP-ase in het binnenoor.