title: Effect of anthelmintics on phosphatases in Ascaridia galli.
abstract: In vitro addition of the drugs tetramisole (TMS) and levamisole (LMS) caused an inhibition of the specific activities of acid phosphatase and Mg(++)-dependent adenosine triphosphatase. The inhibition was non-competitive in nature. No significant inhibition was caused by TMS in the activity of glucose-6-phosphatase, but LMS inhibited the enzyme in a non-competitive manner. The activity of alkaline phosphatase was, however, increased in the presence of both TMS and LMS.
authors.affiliation: Department of Zoology, Panjab University, Chandigarh, India.
authors.forename: R
authors.initials: R
authors.lastname: Aggarwal
authors.forename: S N
authors.initials: SN
authors.lastname: Sanyal
authors.forename: S
authors.initials: S
authors.lastname: Khera
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology*; D001197:Ascaridia / Q000187:drug effects / Q000201:enzymology*; D010744:Phosphoric Monoester Hydrolases / Q000187:drug effects* / Q000378:metabolism
chemical_list: D000871:Anthelmintics; D010744:Phosphoric Monoester Hydrolases