title: [Acute heart insufficiency in an 8-month-old infant presenting with hypocalcemia and Epstein-Barr virus infection: acute myocarditis? Or primary hypokinetic dilated cardiomyopathy?].
abstract: An eight-month-old was admitted for acute congestive heart failure with fever. The respective parts played by hypocalcemia (due to vitamin-D deficiency rickets) and acute Epstein-Barr virus infection are discussed. Hypocalcemia was sufficiently marked to induce heart failure per se but replenishment of calcium stores was followed by only partial improvement in cardiac manifestations. Initial management was difficult because of the risks associated with concomitant administration of calcium and digitalis. After eighteen months during which the patient's status remained stable, evaluation showed that clinical features were consistent with sequelae of acute viral myocarditis. The possibility of primary hypokinetic dilated cardiomyopathy was then considered. Esterified carnitine levels were found to be increased leading to further investigations which outruled mitochondrial cytopathy.
authors.affiliation: Service de Cardiologie, Hôpital Cochin, Paris.
authors.forename: E
authors.initials: E
authors.lastname: Lachassinne
authors.forename: J
authors.initials: J
authors.lastname: Gaudelus
authors.forename: F
authors.initials: F
authors.lastname: Lacombe
authors.forename: A
authors.initials: A
authors.lastname: Lehnert
authors.forename: F
authors.initials: F
authors.lastname: Guerin
authors.forename: A
authors.initials: A
authors.lastname: Vinas
authors.forename: M
authors.initials: M
authors.lastname: Nathanson
authors.forename: C
authors.initials: C
authors.lastname: Durquet-Perelman
authors.forename: R
authors.initials: R
authors.lastname: Perelman
mesh_terms: D000208:Acute Disease; D002311:Cardiomyopathy, Dilated / Q000209:etiology* / Q000382:microbiology; D005260:Female; D006333:Heart Failure / Q000209:etiology* / Q000382:microbiology; D006566:Herpesviridae Infections / Q000150:complications*; D004854:Herpesvirus 4, Human; D006801:Humans; D006996:Hypocalcemia / Q000150:complications*; D007223:Infant; D009205:Myocarditis / Q000209:etiology* / Q000382:microbiology
vernacular_title: Insuffisance cardiaque aiguë chez un nourrisson de huit mois preésentant une hypocalcémie et une infection à virus d'Epstein-Barr: myocardite aiguë? Ou myocardiopathie dilatée hypokinétique primitive?