[Adrenergic mechanisms in the formation of adaptive response of different tissues].
The proliferative tissue activity of the small intestine, kidney, liver and submandibular salivary gland was studied in 10-h immobilization after blocking peripheral beta-adrenoreceptors by obsidan. It is shown that the proliferation increased in all the tissues examined, except the submandibular gland. The injection of obsidan before and during immobilization led to a decrease and delay of DNA synthesis (the intestine, liver), short-term proliferative inhibition (kidney), to stimulation of stress-inhibited proliferation (submandibular gland). It is suggested that the pattern of tissue adaptive response is defined by beta-adrenergic mechanisms.
Dygaĭ
A M
AM
Zakharova
O Iu
OIu
Fomina
T I
TI
Gol'dberg
E D
ED
D000222:Adaptation, Physiological; D000818:Animals; D004247:DNA / Q000096:biosynthesis; D007103:Immobilization; D007413:Intestinal Mucosa / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D011433:Propranolol / Q000494:pharmacology; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000502:physiology*; D013312:Stress, Physiological / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology*; D013363:Submandibular Gland / Q000378:metabolism
D011943:Receptors, Adrenergic, beta; D004247:DNA; D011433:Propranolol
Adrenergicheskie mekhanizmy v formirovanii adaptatsionnogo otveta razlichnykh tkaneĭ.