title: Novobiocin, an antagonist of leukotriene B4.
authors.affiliation: Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Ibaraki, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Tsujii
authors.forename: N
authors.initials: N
authors.lastname: Shigematsu
authors.forename: H
authors.initials: H
authors.lastname: Hatanaka
authors.forename: M
authors.initials: M
authors.lastname: Yamashita
authors.forename: M
authors.initials: M
authors.lastname: Okamoto
authors.forename: M
authors.initials: M
authors.lastname: Okuhara
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D015550:Cell Degranulation / Q000187:drug effects; D002850:Chromatography, Gel; D004195:Disease Models, Animal; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control; D005966:Glucuronidase / Q000378:metabolism; D007975:Leukotriene B4 / Q000037:antagonists & inhibitors*; D051379:Mice; D008807:Mice, Inbred BALB C; D009504:Neutrophils / Q000187:drug effects; D009675:Novobiocin / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D011817:Rabbits; D012871:Skin Diseases / Q000139:chemically induced / Q000517:prevention & control; D013302:Streptomyces / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D009675:Novobiocin; D007975:Leukotriene B4; D005966:Glucuronidase