Hepatitis C virus antibody response in acute and chronic non-A, non-B hepatitis.
Patients with post-transfusion, community-acquired or hemodialysis-acquired non-A, non-B hepatitis (NANBH) were tested for antibody to hepatitis C virus (HCV) during acute-phase and resolving or chronicized illness. HCV appears to be involved in most cases of post-transfusion and hemodialysis-acquired NANBH, but only in 40% of community-acquired NANBH. Second generation HCV antibody assays are more specific and sensitive, favoring early detection of HCV seroconversion and identification of HCV-antibody-positive individuals years after exposure to the virus.
Tagger
A
A
Institute of Virology, University of Milan, Italy.
Ribero
M L
ML
Grossi
A
A
Chiaramonte
S
S
Bortolotti
F
F
Tremolada
F
F
D000328:Adult; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000276:immunology* / Q000635:transmission; D006521:Hepatitis, Chronic / Q000276:immunology; D006801:Humans; D006435:Renal Dialysis / Q000009:adverse effects; D012307:Risk Factors
D006508:Hepatitis Antibodies