Lennert's lymphoma with giant multivesicular lysosomal bodies optically visible.
A case of a 43-year-old male patient with lymphoepithelioid lymphoma is discussed. During the 10-year follow-up of this patient, different biopsy specimens were obtained. Immunohistochemical studies with a complete paraffin panel determined a T-cell nature of the specimens. Electron microscopy showed a peculiar finding in the cytoplasms of the tumoral cells that correlated with optical inclusions observed in optical imprints; these imprints corresponded to lysosomic multivesicular bodies, whose significance is discussed.
Oliva
H
H
Department of Pathology, Fundación Jimenez Diaz, Madrid, Spain.
Rivas
C
C
Vicente
J
J
Aguilera
B
B
Rivas
F
F
Obeso
G
G
Piris
M A
MA
Battifora
H
H
D000328:Adult; D006801:Humans; D002479:Inclusion Bodies / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000648:ultrastructure*; D008247:Lysosomes / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron