Some plasma biochemical changes in experimental Trypanosoma brucei infection of Sokoto Red goats.
Plasma biochemical changes were studied for 8 consecutive weeks in Sokoto Red goats experimentally infected by intravenous route injection of 1.6 x 10(7) Trypanosoma brucei. The strain 8/18 was highly infective. The mean packed cell volume significantly decreased from 1 to 8 weeks post-infection (PI) at P < 0.05. During this period, the mean plasma total bilirubin concentrations significantly increased (P < 0.05). The mean plasma direct and indirect bilirubin concentrations significantly increased from 2 to 8 weeks PI (P < 0.05). The mean plasma albumin concentrations did not vary significantly (P > 0.05), but the mean total plasma proteins and mean plasma globulin concentrations significantly increased between 5 and 8 weeks post infection (P < 0.05). There were no significant changes in the mean plasma bicarbonate, creatinine and cholesterol concentration (P > 0.05).
Igbokwe
I O
IO
Department of Veterinary Pathology, University of Maiduguri, Nigeria.
Mohammed
A
A
D000818:Animals; D015511:Goat Diseases / Q000097:blood*; D006041:Goats; D008297:Male; D009549:Nigeria; D010949:Plasma / Q000469:parasitology; D014346:Trypanosoma brucei brucei; D014353:Trypanosomiasis, African / Q000097:blood / Q000662:veterinary*