Deficits in social behavior in autism and their modification by a synthetic adrenocorticotrophic hormone (4-9) analog.
When charting the structure of the social behavior of autistic children by means of an ethologically analyzed playroom session, deficits appeared in the reciprocity of eye-contact and in the location of verbal initiatives. These deficits in social behavior were beneficially influenced by treatment with the adrenocorticotrophic hormone (4-9) analog ORG 2766.
Buitelaar
J K
JK
Department of Child and Adolescent Psychiatry, Utrecht University Hospital, The Netherlands.
van Engeland
H
H
de Kogel
C H
CH
de Vries
H
H
van Hooff
J A
JA
van Ree
J M
JM
D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D001321:Autistic Disorder / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy / Q000523:psychology; D007360:Intelligence; D010446:Peptide Fragments / Q000627:therapeutic use*; D012919:Social Behavior; D013239:Stereotyped Behavior / Q000187:drug effects
D000927:Anticonvulsants; D010446:Peptide Fragments; C013765:Org 2766; D000324:Adrenocorticotropic Hormone