title: Sclerosing hepatocellular carcinoma with hypercalcemia--a case report.
abstract: A case of sclerosing hepatocellular carcinoma (SHCC) with hypercalcemia was reported. Clinical studies revealed a tumor at the liver hilum with invasion into the bile duct. Light microscopy of the tumor disclosed a moderately differentiated hepatocellular carcinoma (HCC) of the trabecular type with diffuse fibrous stroma. Abundant dense granules were observed in the cytoplasm of the tumor cells with electron microscopy. The elevated serum calcium (13.9 mg/dl) returned to the normal range after resection of the tumor.
authors.affiliation: Department of Internal Medicine, Kurume University School of Medicine, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Yamashita
authors.forename: T
authors.initials: T
authors.lastname: Iwao
authors.forename: T
authors.initials: T
authors.lastname: Torimura
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: K
authors.initials: K
authors.lastname: Hirai
authors.forename: M
authors.initials: M
authors.lastname: Abe
authors.forename: A
authors.initials: A
authors.lastname: Toyonaga
authors.forename: S
authors.initials: S
authors.lastname: Sugihara
authors.forename: M
authors.initials: M
authors.lastname: Kojiro
authors.forename: K
authors.initials: K
authors.lastname: Tanikawa
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000150:complications* / Q000473:pathology; D006801:Humans; D006934:Hypercalcemia / Q000150:complications* / Q000473:pathology; D008113:Liver Neoplasms / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged