[Platelet receptors: nomenclature--structure--function. 1].
Current knowledge on platelet receptors, their structure, function and interaction with their ligands, and the various nomenclatures, is summarized. The role of platelet receptors in thrombosis and hemostasis, and in cell adhesion and invasion, is discussed. Many of the receptors are members of large families of cell-adhesion molecules (such as the integrin family of cell-adhesion receptors) and have common subunits. While some receptors are exclusive to platelets and megakaryocytes (e.g. GP IIb/IIIa), others may be found on several other cell types (such as the receptors for epinephrine or vitronectin). In addition, the receptors for the most important platelet agonists and the platelet binding sites of factors of plasmatic coagulation and fibrinolysis are reviewed.
Beer
J H
JH
Medizinische Universitätsklinik, Inselspital, Bern.
D001665:Binding Sites; D001792:Blood Platelets / Q000378:metabolism*; D015815:Cell Adhesion Molecules / Q000378:metabolism; D006801:Humans; D011956:Receptors, Cell Surface / Q000378:metabolism* / Q000648:ultrastructure; D009626:Terminology as Topic
D015815:Cell Adhesion Molecules; D011956:Receptors, Cell Surface
Plättchenrezeptoren: Nomenklatur--Struktur--Funktion. 1. Teil.