title: [The neuronal reactivity and interaction of the rat cerebral cortex during the microiontophoretic action of acetylcholine in a model negative learning situation].
abstract: Unit activity of 46 pairs of neurons of sensorimotor cortex of rats was studied in a model situation of habituation to repetitive microiontophoretic applications of acetylcholine (ACh). The difference between the types of reactions to ACh of two neighbouring neurons recorded by the same microelectrode was observed on 37% of cases. The difference between the dynamics of activity of neurons with similar patterns of reactions during repetitive action of stimuli was also shown. Stability of the excitatory connections between two neighbouring neurons under the conditions when one of them demonstrated the habituation to repetitive action of ACh were indicated by analysis of cross-correlation histograms.
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Martinson
authors.forename: A A
authors.initials: AA
authors.lastname: Miasnikov
mesh_terms: D000109:Acetylcholine / Q000008:administration & dosage*; D000818:Animals; D002450:Cell Communication / Q000187:drug effects* / Q000502:physiology; D005260:Female; D007478:Iontophoresis; D007858:Learning / Q000187:drug effects* / Q000502:physiology; D008839:Microelectrodes; D009044:Motor Cortex / Q000187:drug effects* / Q000502:physiology; D009433:Neural Inhibition / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D013268:Stimulation, Chemical
chemical_list: D000109:Acetylcholine
vernacular_title: Reaktivnost' i vzaimodeĭstvie neĭronov kory mozga krys pri mikroionoforeticheskom deĭstvii atsetilkholina v model'noĭ situatsii negativnogo naucheniia.