Replacing 99Tcm-DMSA for renal imaging?
We have tried to evaluate the usefulness of an early 99Tcm-MAG3 image, obtained during the second minute after injection of the tracer, in predicting the renal alterations seen on a 99Tcm-DMSA scintigraph, in children clinically suspected of pyelonephritis. It appears that the accuracy of the MAG3 image is population dependent: when, in most of the patients of a study group, DMSA scintigraphy is either normal or very abnormal, the MAG3 image will correctly reflect the DMSA scintigraph. However, when the DMSA alterations are less pronounced, the early MAG3 image will miss the lesions in about 50% of the cases.
Piepsz
A
A
Department of Radioisotopes, AZ VUB, Free University of Brussels, Belgium.
Pintelon
H
H
Verboven
M
M
Keuppens
F
F
Jacobs
A
A
D000208:Acute Disease; D000293:Adolescent; D001530:Belgium / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009842:Oligopeptides; D015609:Organotechnetium Compounds; D011704:Pyelonephritis / Q000000981:diagnostic imaging* / Q000453:epidemiology; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D004113:Succimer; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D017263:Technetium Tc 99m Mertiatide
D009842:Oligopeptides; D015609:Organotechnetium Compounds; D017263:Technetium Tc 99m Mertiatide; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D004113:Succimer