Role of adrenoreactive structures of the amygdaloid complex in the regulation of blood coagulation.
The stimulation of alpha-adrenoreactive structures of the amygdaloid complex, both in isolation and against the background of disengaged beta-adrenoreactive structures, was carried in experiments on male cats in chronic experimental conditions through an implanted chemotrode. It was shown that the alpha-adrenoreactive structures of the amygdaloid complex exert an influence mainly on blood coagulation phases I-II. Blood coagulation phase III changes indirectly through the shortening of phases I-II. The stimulation of beta-adrenoreactive structures of the amygdaloid complex induces the elongation of blood coagulation phases I-III over the duration of the entire experiment. The stimulation of these structures in conditions of the disengagement of the alpha-adrenoreactive structures of the amygdala leads to insignificant changes in phases I-II, after which a hypercoagulation effect is observed. Blood coagulation phase III in these conditions reflects a marked hypocoagulation effect. The data obtained suggest a modulating role of the adrenoreactive structures of the amygdaloid complex in the regulation of the processes of blood coagulation.
Shandra
A A
AA
Department of Normal Physiology, N. I. Pirogov State Medical Institute, Odessa.
Glukhov
V P
VP
D000679:Amygdala / Q000502:physiology*; D000818:Animals; D001777:Blood Coagulation / Q000502:physiology*; D002415:Cats; D004567:Electrodes, Implanted; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology; D011942:Receptors, Adrenergic, alpha / Q000502:physiology*; D011943:Receptors, Adrenergic, beta / Q000502:physiology*
D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D009638:Norepinephrine