title: A municipal level approach to the management of schistosomiasis control in Peri-Peri, MG, Brazil.
abstract: A schistosomiasis control program was implemented between 1974/87 in Peri-Peri, MG (622 inhabitants). Molluscicide (niclosamide) was applied at three monthly intervals in water sources with Biomphalaria glabrata, and individuals eliminating Schistosoma mansoni eggs in the feces were treated annually with oxamniquine. From 1974 to 1983 the control measures were undertaken by staff of the "René Rachou" Research Center FIOCRUZ (CPqRR), and from 1984 to 1987 these measures were included in the Capim Branco basic health network activities. During both periods, the prevalence, incidence, intensity of infection and hepatosplenic form as well as the number of infected snails decreased significantly. The prevalence decreased from 43.5 to 4.4%, the incidence from 19.0 to 2.9%, the overall intensity of S. mansoni from 281 to 87 and of the hepatosplenic form from 5.9 to 0.0%. The results obtained suggest that the municipal management of control measures was as effective as the vertical program conducted by CPqRR staff.
authors.affiliation: Schistosomiasis Lab, Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: P
authors.initials: P
authors.lastname: Coura Filho
authors.forename: R S
authors.initials: RS
authors.lastname: Rocha
authors.forename: M F
authors.initials: MF
authors.lastname: de Lima E Costa
authors.forename: N
authors.initials: N
authors.lastname: Katz
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000818:Animals; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008975:Molluscacides; D009534:Niclosamide; D015995:Prevalence; D012424:Rural Population / Q000706:statistics & numerical data; D012550:Schistosoma mansoni / Q000302:isolation & purification; D012555:Schistosomiasis mansoni / Q000453:epidemiology / Q000469:parasitology / Q000517:prevention & control*
chemical_list: D008975:Molluscacides; D009534:Niclosamide