[The dynamics of the individual profiles of brain asymmetry in patients with craniocerebral trauma under the influence of emoxipin treatment].
The authors studied the effect of the drug emoxypin on the brain functional asymmetry (A) in 36 patients with craniocerebral trauma attended by occurrence of focal traumatic injuries (FTI) to the brain (experimental group). The control group consisted of 61 patients who received the traditional intensive therapy for FTI (isolated brain contusion of moderate and severe degree, intracerebral hematomas measuring 30-50 cm3 in volume in the contusion focus). Favorable changes of the brain FA indices in the individual asymmetry profiles were noted, respectively, in 76.7% and 40.9% of patients given and not given emoxypin. Complete normalization of brain FA indices by the 25th-30th day after the beginning of treatment was recorded in 60.9% of patients in the control group and in 37% of those in the experimental group. The dynamics of individual asymmetry profiles in patients with FTI provides evidence that emoxypin improves the attention, mental efficiency, memory capacity, and selectivity of mnemonic processes.
Fedulov
A S
AS
Teterkina
T I
TI
Oleshkevich
F V
FV
D000975:Antioxidants / Q000627:therapeutic use*; D001924:Brain Concussion / Q000188:drug therapy / Q000503:physiopathology; D001930:Brain Injuries / Q000188:drug therapy* / Q000503:physiopathology; D002543:Cerebral Hemorrhage / Q000188:drug therapy / Q000503:physiopathology; D003422:Critical Care; D004292:Dominance, Cerebral / Q000187:drug effects* / Q000502:physiology; D004341:Drug Evaluation; D006406:Hematoma / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D010847:Picolines / Q000627:therapeutic use*
D000975:Antioxidants; D010847:Picolines; C009820:6-methyl-2-ethyl-3-hydroxypyridine
Dinamika individual'nykh profileĭ asimmetrii mozga u bol'nykh s cherepno-mozgovoĭ travmoĭ pod vliianiem lecheniia émoksipinom.