title: [Hydatidiform mole and its complicated development].
abstract: The authors report a series of 260 cases of trophoblastic disease, followed up over a period of 18 years. Supervision was based on clinical findings, biological development, radiology and ultrasound. The outcome was favourable in 80% of cases with 2.7% requiring prophylactic hysterectomy for classifical hydatiform mole. In the other cases (20%) the following was the way the disease developed: 12 cases of persistent trophoblastic activity, 13 cases of invasive mole, 24 cases of choriocarcinoma. Initially the treatment was with chemotherapy and surgery was used as an extra treatment in 14% of cases, which gave encouraging results. The authors regret three deaths in this series following choriocarcinoma. Two of these were after chemotherapy as a sole treatment and one after treatment with chemotherapy and surgery.
authors.affiliation: Clinique Universitaire de Gynécologie-Obstétrique I, Rabat, Maroc.
authors.forename: A
authors.initials: A
authors.lastname: Chahtane
authors.forename: B
authors.initials: B
authors.lastname: Rhrab
authors.forename: R
authors.initials: R
authors.lastname: Brahmi
authors.forename: A
authors.initials: A
authors.lastname: Chaoui
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D006063:Chorionic Gonadotropin / Q000097:blood; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006785:Hospitals, University; D006801:Humans; D007044:Hysterectomy / Q000706:statistics & numerical data; D015994:Incidence; D008875:Middle Aged; D009018:Morocco / Q000453:epidemiology; D009367:Neoplasm Staging; D010298:Parity; D011159:Population Surveillance; D011247:Pregnancy; D011379:Prognosis; D012189:Retrospective Studies; D014328:Trophoblastic Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000601:surgery; D014594:Uterine Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000601:surgery
chemical_list: D006063:Chorionic Gonadotropin
vernacular_title: La môle hydatiforme et ses évolutions perturbées.