The migraine-dopamine link: do migraine and Parkinson's disease coexist?
The role of the dopaminergic system in the pathogenesis of migraine was studied by evaluating the course of migraine after the onset of Parkinson's disease (PD) in 5 migraineurs. The course of migraine in patients with a family history of migraine was not changed after the onset of PD. On the other hand, in migraineurs without a family history, the migraine attacks either subsided or became shorter and less severe after the onset of PD. These findings may suggest a different role of the dopaminergic system in migraineurs with and without a family history of migraine, and call for a larger survey.
van Hilten
J J
JJ
Department of Neurology, University Hospital, Leiden, The Netherlands.
D000328:Adult; D000368:Aged; D001921:Brain / Q000503:physiopathology; D004298:Dopamine / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000503:physiopathology*; D010300:Parkinson Disease / Q000503:physiopathology*; D011954:Receptors, Dopamine / Q000502:physiology*; D012701:Serotonin / Q000502:physiology
D011954:Receptors, Dopamine; D012701:Serotonin; D004298:Dopamine