title: The putative Na+/H+ antiporter (NapA) of Enterococcus hirae is homologous to the putative K+/H+ antiporter (KefC) of Escherichia coli.
abstract: Two monovalent ion porters, the putative Na+/H+ antiporter (NapA) of Enterococcus hirae and the putative K+/H+ antiporter (KefC) of Escherichia coli, are similar in sequence throughout their hydrophobic domains. These two proteins, which comprise a novel family of transporters unrelated to the previously characterized Na+/H+ exchangers of E. coli (NhaA and NhaB) are proposed to function by essentially the same mechanism.
authors.affiliation: Department of Biology, University of California, San Diego, La Jolla 92093-0116.
authors.forename: J
authors.initials: J
authors.lastname: Reizer
authors.forename: A
authors.initials: A
authors.lastname: Reizer
authors.forename: M H
authors.initials: MH
authors.lastname: Saier
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry* / Q000235:genetics; D001692:Biological Transport; D002352:Carrier Proteins / Q000737:chemistry* / Q000235:genetics; D016983:Enterococcus / Q000737:chemistry* / Q000235:genetics; D004926:Escherichia coli / Q000737:chemistry* / Q000235:genetics; D006859:Hydrogen / Q000737:chemistry; D008969:Molecular Sequence Data; D011188:Potassium / Q000737:chemistry; D027961:Potassium-Hydrogen Antiporters; D016415:Sequence Alignment; D012964:Sodium / Q000737:chemistry; D017923:Sodium-Hydrogen Exchangers
chemical_list: D001426:Bacterial Proteins; D002352:Carrier Proteins; D027961:Potassium-Hydrogen Antiporters; D017923:Sodium-Hydrogen Exchangers; D006859:Hydrogen; D012964:Sodium; D011188:Potassium