[The characteristics of the opioid regulation of the afferent reactions of the stomach and duodenum to the early stages of their acute damage].
Acute cat experiments were conducted to study the effect of naloxone, moradol and dalargin on the formation of afferent reactions of gastroduodenal complex components by registration of cortical and subcortical evoked potentials during electrostimulation of the stomach and duodenum at an early stage of their acute lesion. It is found that agonists and antagonists of opiate receptors prevent the depression of afferentation of gastroduodenal complex components early after acute lesion. It is suggested that the main mechanism underlying the depression of gastric and duodenal afferent reactions at early post-alteration period may be related to activation of intraorganic opioid systems.
Sheveleva
O A
OA
Bugorskiĭ
G V
GV
Zav'ialov
A V
AV
Privalova
I L
IL
D000344:Afferent Pathways / Q000187:drug effects / Q000502:physiology; D000818:Animals; D002077:Butorphanol / Q000494:pharmacology; D002415:Cats; D002540:Cerebral Cortex / Q000187:drug effects / Q000502:physiology; D004386:Duodenum / Q000187:drug effects / Q000502:physiology*; D004558:Electric Stimulation; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives / Q000494:pharmacology; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology; D005557:Formaldehyde / Q000633:toxicity; D009270:Naloxone / Q000494:pharmacology; D011957:Receptors, Opioid / Q000187:drug effects / Q000502:physiology*; D013270:Stomach / Q000187:drug effects / Q000502:physiology*; D013788:Thalamus / Q000187:drug effects / Q000502:physiology; D013997:Time Factors
D011957:Receptors, Opioid; D005557:Formaldehyde; D009270:Naloxone; D016308:Enkephalin, Leucine-2-Alanine; D002077:Butorphanol; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Osobennosti opioidnykh reguliatsiĭ afferentnykh reaktsiĭ zheludka i dvenadtsatiperstnoĭ kishki na rannikh étapakh ikh ostrogo povrezhdeniia.