title: Active oxygen species, articular inflammation and cartilage damage.
abstract: Rheumatoid arthritis and osteoarthritis are age-related diseases, in which degenerative changes (arthrosis) and superimposed inflammatory reactions (arthritis) lead to progressive destruction of the joints. Active oxygen species derived from various sources play a role in this process, which may be influenced by appropriate treatment with antioxidants and free radical scavengers.
authors.affiliation: Laboratory of Radioimmunoassay, University Sart-Tilman, Liége, Belgium.
authors.forename: Y
authors.initials: Y
authors.lastname: Henrotin
authors.forename: G
authors.initials: G
authors.lastname: Deby-Dupont
authors.forename: C
authors.initials: C
authors.lastname: Deby
authors.forename: P
authors.initials: P
authors.lastname: Franchimont
authors.forename: I
authors.initials: I
authors.lastname: Emerit
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use*; D001168:Arthritis / Q000188:drug therapy / Q000503:physiopathology*; D002358:Cartilage, Articular / Q000254:growth & development / Q000503:physiopathology; D004249:DNA Damage; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D006878:Hydroxides / Q000378:metabolism; D017665:Hydroxyl Radical; D007249:Inflammation; D007596:Joints / Q000254:growth & development / Q000503:physiopathology; D015227:Lipid Peroxidation; D014969:Xanthine Oxidase / Q000378:metabolism
chemical_list: D000975:Antioxidants; D005609:Free Radicals; D006878:Hydroxides; D017665:Hydroxyl Radical; D014969:Xanthine Oxidase