Hepatitis C virus (HCV) and autoimmune liver diseases.
Anti-HCV tests were positive in 18-45% of sera from patients with autoimmune chronic active hepatitis. High gammaglobulin levels may result in false positive results, however, some sera show true positivity. PCR testing of such sera is necessary in order to determine whether HCV is directly involved in specific forms of the disease.
Meyer zum Büschenfelde
K H
KH
I. Medizinische Klinik und Poliklinik, Johannes Gutenberg Universität Mainz, Federal Republic of Germany.
Gerken
G
G
Manns
M
M
D000956:Antigens, Viral; D001327:Autoimmune Diseases / Q000150:complications / Q000276:immunology*; D005500:Follow-Up Studies; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000150:complications / Q000276:immunology*; D006521:Hepatitis, Chronic / Q000150:complications / Q000276:immunology*; D006801:Humans; D007165:Immunosuppression Therapy; D008107:Liver Diseases / Q000150:complications / Q000276:immunology*; D017361:Viral Nonstructural Proteins; D014764:Viral Proteins / Q000276:immunology
D000956:Antigens, Viral; C064544:C100 protein, hepatitis C virus; D006508:Hepatitis Antibodies; D017361:Viral Nonstructural Proteins; D014764:Viral Proteins