title: [Overall analysis of structural factors responsible for the activity and toxicity of antiparasitic agents used in therapy].
abstract: A mini-data bank was constituted from the 73 french antiparasitic patent medicines and was implanted in microcomputer. A maximum of chemical, pharmaceutical, therapeutical and toxicological data were collected and treated by multivariate analysis. Exploitation of these informations processing allows to take out correlations between chemical structure toxicity, and specificity.
authors.affiliation: Faculté de Pharmacie, Tours, France.
authors.forename: J
authors.initials: J
authors.lastname: Lacroix
authors.forename: J C
authors.initials: JC
authors.lastname: Dore
authors.forename: C
authors.initials: C
authors.lastname: Viel
authors.forename: R
authors.initials: R
authors.lastname: Lacroix
authors.forename: F
authors.initials: F
authors.lastname: Beliveau
authors.forename: F
authors.initials: F
authors.lastname: Reynouard
mesh_terms: D000871:Anthelmintics / Q000009:adverse effects* / Q000494:pharmacology; D000981:Antiprotozoal Agents / Q000009:adverse effects* / Q000494:pharmacology; D006801:Humans; D013329:Structure-Activity Relationship
chemical_list: D000871:Anthelmintics; D000981:Antiprotozoal Agents
vernacular_title: Analyse globale des facteurs structuraux responsables de l'activité et de la toxicité des antiparasitaires utilisés en thérapeutique.