title: The role of radiotherapy in patients with advanced seminomatous germ cell tumors. Controversies in management. Part 2.
abstract: The role of radiotherapy in the management of advanced seminomatous germ cell tumors remains controversial. The authors review the available literature, and recommend radiotherapy for stage II seminoma with bulky abdominal metastases (greater than 10 cm) under the following circumstances: As primary therapy only if the patient cannot or will not be treated with chemotherapy; as an adjuvant following chemotherapy in patients with residual masses of any size. Similar recommendations are made regarding the role of radiotherapy in the management of extragonadal seminoma outside the central nervous system.
authors.affiliation: Department of Radiation Oncology, Duke Comprehensive Cancer Center, Duke University Medical Center, Durham, North Carolina.
authors.forename: M S
authors.initials: MS
authors.lastname: Anscher
authors.forename: L B
authors.initials: LB
authors.lastname: Marks
authors.forename: W U
authors.initials: WU
authors.lastname: Shipley
mesh_terms: D004407:Dysgerminoma / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*