title: Fatigue and changes of ATP, creatine phosphate, and lactate during the 400-m sprint.
abstract: Fatigue during the 400-m sprint was studied by measuring muscle ATP, creatine phosphate (CP), lactate (M-La), and blood lactate (B-La) in six male runners before and after four experimental sprints (100, 200, 300, and 400 m). During the first 100 m, muscle CP decreased from 15.8 +/- 1.7 to 8.3 +/- 0.3 mmol/kg while M-La increased to 3.6 +/- 0.4 mmol/kg. After 200 m the CP had decreased to 6.5 +/- 0.5 mmol/kg and M-La had increased to 8.3 +/- 1.1 mmol/kg. At the end of the 400 meters, ATP and CP concentrations had decreased by 27% and 89%, respectively, and M-La had increased to 17.3 +/- 0.9 mmol/kg. It was concluded that after 200 m the speed of running decreased, although CP was not depleted and lactate concentration was not at maximum level. Complete fatigue occurred when CP stores were depleted and B-La and M-La attained an individual maximum.
authors.affiliation: Finnish Sports Institute, Vierumäki, Finland.
authors.forename: J
authors.initials: J
authors.lastname: Hirvonen
authors.forename: A
authors.initials: A
authors.lastname: Nummela
authors.forename: H
authors.initials: H
authors.lastname: Rusko
authors.forename: S
authors.initials: S
authors.lastname: Rehunen
authors.forename: M
authors.initials: M
authors.lastname: Härkönen
mesh_terms: D000255:Adenosine Triphosphate / Q000032:analysis* / Q000097:blood / Q000378:metabolism; D005221:Fatigue; D005260:Female; D006801:Humans; D007773:Lactates / Q000032:analysis* / Q000097:blood; D008297:Male; D009132:Muscles / Q000378:metabolism*; D010725:Phosphocreatine / Q000032:analysis* / Q000097:blood / Q000378:metabolism; D012420:Running
chemical_list: D007773:Lactates; D010725:Phosphocreatine; D000255:Adenosine Triphosphate