[Early and late results of myocardial revascularization after coronary thrombolysis with intravenous streptokinase in the treatment of acute myocardial infarction].
OBJECTIVE
To study the early and late results of patients treated initially intravenous streptokinase and then with coronary artery bypass surgery.


METHODS
One hundred and twenty one patients with acute myocardial infarction less than 6 hours duration were treated initially with intravenous streptokinase, and 1-38 days after (median 8.80 days) coronary artery bypass was undertaken. Ninety six patients were operated with extracorporeal circulation and 25 without it.


RESULTS
Overall operative mortality was 3.30% (4/121). Reoperations due to bleeding was necessary in 3.30% (4/121). Late mortality was 5.40% with survival probability of 94.60% after 36 months and 92.30% after 70 months. Late morbidity events in terms of angina and cardiac insufficiency demonstrated that 7 patients had angina, 4 cardiac insufficiency and two angina and cardiac insufficiency; probability to be free from these events was 88.20% after 46 months and 66.40% after 70 months.


CONCLUSIONS
Coronary artery bypass surgery after intravenous streptokinase can be undertaken with security and excellent early and late results.
Vega
H
H
UNICOR, São Paulo.
Leão
L E
LE
Andrade
J C
JC
Ribeiro
E
E
Silva
L
L
La Rotta
C
C
Tavares
J R
JR
Buffolo
E
E
D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality / Q000628:therapy*; D009204:Myocardial Revascularization; D013300:Streptokinase / Q000627:therapeutic use*; D015912:Thrombolytic Therapy
D013300:Streptokinase
Resultados imediatos e tardios da revascularização cirúrgica do miocárdio pós-trombólise coronariana com estreptoquinase intravenosa no tratamento do infarto agudo do miocárdio.