title: A theoretical method to predict DNA permutation gel electrophoresis from the sequence.
abstract: The gel electrophoretic permutation assays of DNA fragments experimentally investigated by different authors were theoretically reproduced using our theoretical model of sequence-dependent curvature. The general pattern of agreement obtained suggests that our method can be usefully adopted as an alternative to the experimental assay, in particular where the lack of a sufficient number of unique restriction sites in the fragment prevents the correct localization of the main bend site.
authors.affiliation: Dipartimento di Chimica, Università di Roma, La Sapienza, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Boffelli
authors.forename: P
authors.initials: P
authors.lastname: De Santis
authors.forename: A
authors.initials: A
authors.lastname: Palleschi
authors.forename: G
authors.initials: G
authors.lastname: Risuleo
authors.forename: M
authors.initials: M
authors.lastname: Savino
mesh_terms: D004247:DNA / Q000737:chemistry*; D004279:DNA, Viral / Q000737:chemistry; D004591:Electrophoresis, Polyacrylamide Gel; D008956:Models, Chemical; D009690:Nucleic Acid Conformation; D013539:Simian virus 40 / Q000235:genetics
chemical_list: D004279:DNA, Viral; D004247:DNA