[Therapy of neuropathies with a vitamin B combination. Symptomatic treatment of painful diseases of the peripheral nervous system with a combination preparation of thiamine, pyridoxine and cyanocobalamin].
METHODS
In an open, multicentric observational study involving 234 doctors in private practice, the evolution of symptoms and the tolerability of a vitamin B preparation (Neurotrat forte) used as treatment in 1,149 patients with polyneuropathy, neuralgia, radiculopathy and neuritis associated with pain and paresthesias, were observed. The form of administration (ampoules, dragées), dosage and duration of treatment were left to the individual care-providing physician. The target symptoms evaluated were intensity of pain, muscle weakness affecting the legs, and paresthesia.


RESULTS
Under treatment, there was a clear improvement in these symptoms. At a second examination approximately three weeks after initiation of treatment, a positive effect on pain in particular was observed in 69% of the cases. Similar observations were also made for paresthesias and muscular weakness in the legs.
Eckert
M
M
St. Marienhospital, Lünen.
Schejbal
P
P
D003929:Diabetic Neuropathies / Q000188:drug therapy / Q000209:etiology; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000188:drug therapy* / Q000209:etiology; D009460:Neurologic Examination / Q000187:drug effects; D010523:Peripheral Nervous System Diseases / Q000188:drug therapy* / Q000209:etiology; D011736:Pyridoxine / Q000008:administration & dosage*; D013831:Thiamine / Q000008:administration & dosage*; D014805:Vitamin B 12 / Q000008:administration & dosage*
D004338:Drug Combinations; D011736:Pyridoxine; D014805:Vitamin B 12; D013831:Thiamine
Therapie von Neuropathien mit einer Vitamin-B-Kombination. Symptomatische Behandlung von schmerzhaften Erkrankungen des peripheren Nervensystems mit einem Kombinationspräparat aus Thiamin, Pyridoxin und Cyanocobalamin.