Seroprevalence of bovine immunodeficiency-like virus and bovine leukemia virus in a dairy cattle herd.
To determine the prevalence of single vs. dual infection with bovine immunodeficiency virus (BIV) and bovine leukemia virus (BLV), sera (n = 95) from a dairy cattle herd were analyzed for anti-BIV and anti-BLV antibodies by an enzyme linked immunosorbent assay. Twenty-one percent (20/95) of samples were BIV-seropositive, while 52% (49/95) of the same samples were BLV-seropositive. A significantly greater percentage of BIV-seronegative samples were BLV-seropositive, 57% (43/75), than were BIV-seropositive samples, 30% (6/20). There was no significant correlation between data ranked from least to greatest amount of anti-viral antibody. Five cattle had persistent lymphocytosis (PL); all five were BLV-seropositive and two were BIV-positive. The mean anti-BLV titer was significantly greater in PL cattle, as compared at non-PL cattle, whereas there was no significant difference between the mean anti-BIV titer in PL cattle, as compared with non-PL cattle. These results provide additional information on the seroprevalence of naturally occurring BIV infection, and indicate that BIV can exist independent of other common infectious agents, such as BLV. Further, the results suggest that infection with BIV is not associated with an increased rate of infection with other infectious agents such as BLV.
Cockerell
G L
GL
Department of Pathology, Colorado State University, Fort Collins 80523.
Jensen
W A
WA
Rovnak
J
J
Ennis
W H
WH
Gonda
M A
MA
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology*; D016583:Enzootic Bovine Leukosis / Q000453:epidemiology*; D004797:Enzyme-Linked Immunosorbent Assay; D016087:Immunodeficiency Virus, Bovine / Q000276:immunology*; D016180:Lentivirus Infections / Q000453:epidemiology / Q000662:veterinary*; D001909:Leukemia Virus, Bovine / Q000276:immunology*; D015995:Prevalence
D000914:Antibodies, Viral