[Danazol action on 5'-nucleotidase activity in mouse peritoneal macrophages].
The paper reports the results of danazol action in vivo and in vitro on 5'-nucleotidase activity of mouse peritoneal macrophages. The results showed, that danazol at a concentration of 10 M (the pharmacologic level in women taking 600 mg/day) significantly stimulated the enzyme activity.
Mit'kin
V V
VV
Volkov
N I
NI
Pshenichnikova
T Ia
TIa
Sukhikh
G T
GT
D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism; D003613:Danazol / Q000494:pharmacology*; D066298:In Vitro Techniques; D008264:Macrophages / Q000187:drug effects / Q000201:enzymology*; D051379:Mice; D008810:Mice, Inbred C57BL; D009708:Nucleotidases / Q000187:drug effects* / Q000378:metabolism; D010537:Peritoneum; D013268:Stimulation, Chemical
D000242:Cyclic AMP; D009708:Nucleotidases; D003613:Danazol
Deĭstvie danazola na aktivnost' 5'-nukleotidazy peritoneal'nykh makrofagov mysheĭ.