title: Lichen planus, liver kidney microsomal (LKM1) antibodies and hepatitis C virus antibodies.
abstract: No anti-liver kidney microsomal (LKM1) antibodies were detected in 46 patients with LP, 16 of whom had also a chronic liver disease (CLD). In contrast, anti-hepatitis C virus (HCV) antibodies were found in 10% of patients with LP and in 50% of those with LP and CLD. Anti-HCV antibodies may be considered as a false-positive reaction in 56% of cases, especially when anti-LKM1 antibodies are present. Our findings do not support such a hypothesis, but suggest that CLD in LP patients is, at least in Italy, mostly a postviral chronic active hepatitis.
authors.affiliation: Department of Dermatology, University of Genoa, Italy.
authors.forename: M C
authors.initials: MC
authors.lastname: Divano
authors.forename: A
authors.initials: A
authors.lastname: Parodi
authors.forename: A
authors.initials: A
authors.lastname: Rebora
mesh_terms: D001323:Autoantibodies / Q000097:blood*; D002908:Chronic Disease; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D005260:Female; D005455:Fluorescent Antibody Technique; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006515:Hepatitis B virus / Q000276:immunology; D006801:Humans; D008010:Lichen Planus / Q000150:complications / Q000276:immunology*; D008107:Liver Diseases / Q000150:complications / Q000276:immunology*; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies
chemical_list: D001323:Autoantibodies; D006508:Hepatitis Antibodies; C060729:anti-liver kidney microsome antibody