title: [Synthesis of nucleoside 5'-fluoroalkylphosphonate--compounds with potential antiviral properties].
abstract: Several 5'-fluoroalkylphosphonates of 3'-azido-3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine were synthesized as potential antiviral compounds. Fluoromethyl, difluoromethyl, fluorochloromethyl and vinyl phosphonates were used as phosphonylating components, with dicyclohexylcarbodiimide or triisopropylbenzenesulphonyl chloride as condensing reagents.
authors.forename: N B
authors.initials: NB
authors.lastname: Diatkina
authors.forename: M V
authors.initials: MV
authors.lastname: Ias'ko
authors.forename: A A
authors.initials: AA
authors.lastname: Arzumanov
authors.forename: A A
authors.initials: AA
authors.lastname: Kraevskiĭ
authors.forename: F M
authors.initials: FM
authors.lastname: Semchenko
authors.forename: O G
authors.initials: OG
authors.lastname: Eremin
authors.forename: B I
authors.initials: BI
authors.lastname: Martynov
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis*; D015224:Dideoxynucleosides / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D009943:Organophosphorus Compounds / Q000138:chemical synthesis*; D018119:Stavudine; D015215:Zidovudine / Q000031:analogs & derivatives* / Q000138:chemical synthesis
chemical_list: D000998:Antiviral Agents; D015224:Dideoxynucleosides; D009943:Organophosphorus Compounds; D015215:Zidovudine; D018119:Stavudine
vernacular_title: Sintez 5'-ftoralkilfosfonatov nukleosideov--soedineniĭ s potentsial'nymi protivovirusnymi svoĭstvami.