Elevation of serum erythropoietin after subtotal parathyroidectomy in chronic haemodialysis patients.
After successful subtotal parathyroidectomy (PTX) in 10 chronic haemodialysis patients, significant elevation of Epo was observed, from 48.4 +/- 17.8 mU/ml(M +/- SEM) at preoperative state to 103.3 +/- 34.7 mU/ml at 6 h and 163.4 +/- 50.2 mU/ml at 12 h after PTX. Significant reductions in both PTH-m and ionized calcium (iCa) were confirmed. Since Epo did not increase in the cases with an inadequate PTX and ovariectomy, an abrupt reduction in PTH with a decrease in iCa may play some role in the elevation of Epo.
Washio
M
M
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka City, Japan.
Iseki
K
K
Onoyama
K
K
Oh
Y
Y
Nakamoto
M
M
Fujimi
S
S
Fujishima
M
M
D000328:Adult; D000368:Aged; D000740:Anemia / Q000097:blood / Q000209:etiology; D004921:Erythropoietin / Q000097:blood*; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000601:surgery; D007676:Kidney Failure, Chronic / Q000097:blood / Q000150:complications / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010052:Ovariectomy; D016105:Parathyroidectomy; D006435:Renal Dialysis / Q000009:adverse effects
D004921:Erythropoietin