title: [Developmental and involutional breast disorders].
abstract: The majority of benign breast disorders may be classified as developmental and involutive. Mastalgia and breast nodularity represent the greatest groups of these disorders, while epithelial hyperplasia is a complex benign disorder which is most difficult to be evaluated. Sixty women with diagnosis of cyclic mastalgia and 30 with noncyclic breast pain were followed-up. Patients were administered bromocryptine, danazol or a local progestogel. Better treatment results were achieved in cyclic mastalgia than in women with noncyclic mastalgia. One hundred and forty-five biopsies of the benign breast tissue were examined histologically. Nonproliferative forms were found in 66.9% of the women, proliferative without atypia in 29.65%, and proliferative with atypia in 3.45% of the patients. Atypical ductal hyperplasia and atypical lobular hyperplasia increase four-to fivefold the risk for breast cancer. Prophylactic subcutaneous or total mastectomy is not as a rule indicated in atypical epithelial hyperplasia, only regular follow-up is required.
authors.affiliation: Klinika za Kirurgiju, KBC, Medicinski fakultet Sveucilista u Zagrebu.
authors.forename: I
authors.initials: I
authors.lastname: Prpić
authors.forename: J
authors.initials: J
authors.lastname: Jakić-Razumović
authors.forename: B
authors.initials: B
authors.lastname: Oberman
authors.forename: D
authors.initials: D
authors.lastname: Montani
authors.forename: R
authors.initials: R
authors.lastname: Ivrlac
authors.forename: J
authors.initials: J
authors.lastname: Unusić
authors.forename: Z
authors.initials: Z
authors.lastname: Stanec
authors.forename: D
authors.initials: D
authors.lastname: Hulina
authors.forename: I
authors.initials: I
authors.lastname: Depina
mesh_terms: D000328:Adult; D001941:Breast Diseases / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010146:Pain
vernacular_title: Razvojna i involucijska poremećenja dojke.