The bioactivity of insulin analogues from in vitro receptor binding to in vivo glucose uptake.
Drejer
K
K
Diabetes Research, Novo Nordisk A/S, Bagsvaerd, Denmark.
D000595:Amino Acid Sequence; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002455:Cell Division / Q000187:drug effects; D006133:Growth Substances / Q000494:pharmacology; D006801:Humans; D007328:Insulin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D007700:Kinetics; D008958:Models, Molecular; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D017526:Receptor, IGF Type 1 / Q000378:metabolism; D011972:Receptor, Insulin / Q000378:metabolism*; D011994:Recombinant Proteins / Q000378:metabolism / Q000494:pharmacology
D001786:Blood Glucose; D006133:Growth Substances; D007328:Insulin; D011994:Recombinant Proteins; D011505:Protein-Tyrosine Kinases; D017526:Receptor, IGF Type 1; D011972:Receptor, Insulin