Transmission of herpes simplex virus infection via lacrimal canaliculi.
We analyzed the differentiation of two strains isolated from the conjunctiva and rhinorrhea of a patient with herpetic keratitis by the restriction endonuclease digestion method of herpes simplex virus (HSV) DNA. As a result two strains were identified as the same one. This result suggests that HSV contained in tears flows into the nasal cavity via the lacrimal canaliculi.
Yoshida
M
M
Department of Dermatology, Kinki University School of Medicine, Osaka, Japan.
Hondo
R
R
D002675:Child, Preschool; D003228:Conjunctiva / Q000382:microbiology*; D005260:Female; D006801:Humans; D016849:Keratitis, Herpetic / Q000382:microbiology / Q000635:transmission*; D009297:Nasal Mucosa / Q000382:microbiology; D009301:Nasolacrimal Duct / Q000382:microbiology*; D012008:Recurrence; D018139:Simplexvirus / Q000302:isolation & purification