title: Experience with plasmin inhibitors.
abstract: The involvement and role of the plasminogen activator-plasmin system in normal and pathological wound healing is reviewed. The methods currently available for demonstrating plasmin activity are briefly described. The article also reviews some other serine proteases potentially involved in pathological wound healing processes. The current ophthalmological therapeutic measures used to regulate tissue proteolysis are also described.
authors.affiliation: Department of Ophthalmology, University of Helsinki, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Tervo
authors.forename: G B
authors.initials: GB
authors.lastname: van Setten
authors.forename: K
authors.initials: K
authors.lastname: Tervo
authors.forename: A
authors.initials: A
authors.lastname: Tarkkanen
mesh_terms: D003315:Cornea / Q000378:metabolism / Q000503:physiopathology*; D003320:Corneal Ulcer / Q000378:metabolism / Q000503:physiopathology; D005341:Fibrinolysin / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D010958:Plasminogen / Q000378:metabolism; D010960:Plasminogen Activators; D012697:Serine Endopeptidases / Q000378:metabolism; D013666:Tears / Q000378:metabolism; D014945:Wound Healing
chemical_list: D010958:Plasminogen; D010960:Plasminogen Activators; D012697:Serine Endopeptidases; D005341:Fibrinolysin