A novel subunit ISCOM vaccine against bovine virus diarrhoea virus.
The preparation and preliminary testing of a subunit ISCOM (immunostimulating complex) vaccine against bovine virus diarrhoea virus (BVDV) is described. Vaccination of calves with this vaccine yields high neutralising titres against a panel of Danish BVDV field isolates. The serological difference between virus isolates and vaccine strain selection is discussed.
Kamstrup
S
S
Ministry of Agriculture, State Veterinary Institute for Virus Research, Kalvehave, Denmark.
Rønsholt
L
L
Jensen
M H
MH
Dalsgaard
K
K
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000517:prevention & control*; D002417:Cattle; D001908:Diarrhea Viruses, Bovine Viral / Q000276:immunology*; D016882:ISCOMs; D014611:Vaccination / Q000662:veterinary*; D014765:Viral Vaccines / Q000276:immunology
D000914:Antibodies, Viral; D016882:ISCOMs; D014765:Viral Vaccines