G protein-activation inhibits smooth muscle MLC phosphatase to increase the contractile sensitivity to Ca2+.
Kitazawa
T
T
Department of Physiology, University of Virginia, Charlottesville 22908.
Masuo
M
M
Somlyo
A P
AP
D000818:Animals; D001711:Biotransformation; D002118:Calcium / Q000494:pharmacology*; D019204:GTP-Binding Proteins / Q000378:metabolism*; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000201:enzymology*; D043263:Myosin-Light-Chain Phosphatase; D010749:Phosphoprotein Phosphatases / Q000378:metabolism*; D011817:Rabbits
D010749:Phosphoprotein Phosphatases; D043263:Myosin-Light-Chain Phosphatase; D019204:GTP-Binding Proteins; D002118:Calcium