[The interaction of taurine and beta-alanyl-L-histidine (carnosine) with hypochlorite anion (ClO-)].
Dipeptide carnosine and amino acid taurine have been found to actively interact with hypochlorite anion. Chloramine complexes obtained during this reaction were more stable in case of taurine. It is suggested that therapeutic effect of new Russian eye drops taufon and sevitin is due to neutralization of the reaction product hypochlorite anion catalyzed by myeloperoxidase.
Gorshkova
T N
TN
Formaziuk
V E
VE
Sergienko
V I
VI
Dudina
E I
EI
D000838:Anions; D002336:Carnosine / Q000032:analysis / Q000494:pharmacology*; D004347:Drug Interactions; D006997:Hypochlorous Acid / Q000032:analysis / Q000494:pharmacology*; D012996:Solutions; D013056:Spectrophotometry, Ultraviolet; D013654:Taurine / Q000032:analysis / Q000494:pharmacology*
D000838:Anions; D012996:Solutions; D013654:Taurine; D006997:Hypochlorous Acid; D002336:Carnosine
Vzaimodeĭstvie taurina i beta-alanil-L-gistidina (karnozina) s gipokhlorit-anionom (ClO-).