[Detection of human papillomavirus (H.P.V.) DNA in genital lesions using molecular hybridization].
Detection of human papilloma virus in genitals lesions by molecular hybridization. Some H.P.V. types are sexually transmitted and infect genital organs. We have used molecular hybridization to examine the distribution of H.P.V. 6 or II and H.P.V. 16 in benign, premalignant and malignant genital lesions from 344 patients. The frequency of H.P.V. 16 positive cases increases as the cervical lesions progress to malignancy: 57/78 are positive (73%) in the carcinomas, 29/83 are positive (35%) in mild or moderate dysplasia. The majority of benign condylomata acuminata harbors DNA of other types, namely H.P.V. 6 and II.
Meguenni
S
S
Service de Virologie, Institut Pasteur d'Algérie.
el-Mehdaoui
S
S
Bandoui
D
D
Bouguermouh
A
A
Allouache
A
A
Bendib
A
A
Chouiter
A
A
Djenaoui
T
T
Lalliam
N
N
Bouhadef
A
A
D015139:Blotting, Southern; D002277:Carcinoma / Q000382:microbiology*; D002278:Carcinoma in Situ / Q000382:microbiology; D003218:Condylomata Acuminata / Q000382:microbiology*; D015344:DNA Probes, HPV; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D005833:Genital Neoplasms, Female / Q000382:microbiology*; D006801:Humans; D009361:Neoplasm Invasiveness; D009693:Nucleic Acid Hybridization; D027383:Papillomaviridae / Q000145:classification / Q000302:isolation & purification*; D014412:Tumor Virus Infections / Q000382:microbiology*; D002578:Uterine Cervical Dysplasia / Q000382:microbiology*; D002583:Uterine Cervical Neoplasms / Q000382:microbiology
D015344:DNA Probes, HPV; D004279:DNA, Viral
Détection du DNA des virus du papillomme humain (H.P.V.) dans les lésions génitales par hybridation moléculaire.