title: [Hemodynamics in skin and tissue expansion].
abstract: The capillary blood flow (CBF) of the random flaps constructed on expanded and unexpanded skin of dogs was determined by radioactive microsphere technique. The CBF was significantly higher (P < 0.001) in the skin flaps of the expanded group (387 +/- 23 microliters/min/flap) than that of the acute group (127 +/- 16 microliters/min/flap). There were no significant differences in the expanded group, the delayed group (374 +/- 35 microliters/min/flap) and the control group (389 +/- 48 microliters/min/flap). Even at the pedicle site, the CBF of the acute group was already significantly lower than that of other three groups (P < 0.001). The general tendency of gradual CBF reduction from the pedicle to the distal end of all the flaps was observed. The CBF at the point 8cm from the pedicle of the acute group was 12 microliters/min/g, whereas in other three groups, at point 13 cm from the pedicle the CBF was 12 microliters/min/g. The results suggested that during skin expansion the area of skin is enlarged, and its CBF and survival length may be increased. The problem of capsulectomy during flap construction was discussed.
authors.affiliation: General Hospital, Jinan Unit of People's Liberation Army, Jinan.
authors.forename: Z W
authors.initials: ZW
authors.lastname: He
mesh_terms: D000818:Animals; D004285:Dogs; D006439:Hemodynamics; D008833:Microcirculation; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply* / Q000503:physiopathology; D013524:Surgical Flaps; D015626:Tissue Expansion