Antiviral activity of some copper complexes of symmetrical triazines.
Copper complexes of hydrazones derived from symmetrical triazines inhibit the multiplication of three different types of viruses (Sendai, HSV and VSV) showing as well a scavenger activity on O2- radicals. The results emphasize the antiviral activity of these complexes which have at the same time a O2- radical scavenger activity.
Popescu
A
A
Stefan S. Nicolau Institute of Virology, Bucharest, Romania.
Zuivertz
A
A
Olinescu
R
R
Tomas
S
S
Tomas
E
E
Jucu
V
V
D000998:Antiviral Agents / Q000494:pharmacology*; D002478:Cells, Cultured / Q000382:microbiology; D003300:Copper / Q000494:pharmacology*; D005347:Fibroblasts / Q000382:microbiology; D006801:Humans; D008163:Luminescent Measurements; D010222:Parainfluenza Virus 1, Human / Q000187:drug effects; D018139:Simplexvirus / Q000187:drug effects; D013329:Structure-Activity Relationship; D014227:Triazines / Q000494:pharmacology*; D014721:Vesicular stomatitis Indiana virus / Q000187:drug effects
D000998:Antiviral Agents; D014227:Triazines; D003300:Copper