title: Malignant rhabdoid tumour of the liver. A case report.
abstract: A case of primary malignant rhabdoid tumour of the liver occurring in a 5-month-old girl is reported. Histologically the neoplasm presented the 'typical' features as described in malignant rhabdoid tumour arising in the kidney. In addition, some areas of the tumour showed a 'pseudoglandular' growth pattern. Immunohistochemistry revealed the neoplastic cells to be intensively positive for vimentin and for cytokeratin 19. Variable immunoreactivity for cytokeratin polypeptides 7, 8 and 19 was also detected. On electronmicroscopy the neoplastic cells contained bundles of intermediate filaments, tonofilaments and intercellular junctions. These findings are suggestive of a primitive epithelial differentiation.
authors.affiliation: Pathology Department II, UZ St Rafaël, Leuven, Belgium.
authors.forename: M P
authors.initials: MP
authors.lastname: Foschini
authors.forename: P
authors.initials: P
authors.lastname: Van Eyken
authors.forename: P R
authors.initials: PR
authors.lastname: Brock
authors.forename: M
authors.initials: M
authors.lastname: Casteels-Van Daele
authors.forename: R
authors.initials: R
authors.lastname: De Vos
authors.forename: P
authors.initials: P
authors.lastname: Dal Cin
authors.forename: H
authors.initials: H
authors.lastname: Van den Berghe
authors.forename: V J
authors.initials: VJ
authors.lastname: Desmet
mesh_terms: D015415:Biomarkers; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D008113:Liver Neoplasms / Q000737:chemistry* / Q000473:pathology* / Q000648:ultrastructure; D009396:Wilms Tumor / Q000737:chemistry* / Q000473:pathology* / Q000648:ultrastructure
chemical_list: D015415:Biomarkers