title: [Invasive aspergillosis in immunocompromised patients. An analysis of 57 patients].
abstract: Fifty seven cases of invasive aspergillosis have been analyzed. Most patients were severely neutropenic. The main underlying diseases were acute leukemia, malignant lymphoma and bone marrow transplantation. The clinical and radiological manifestations and the mycological data rare presented. A dramatic increase of the annual incidence has been observed since 1986. The main causes appear to be the increase in intensity of chemotherapy regimen for acute leukemia and the progressive colonisation of a part the department. Overall mortality is especially high (74%) but the mortality rate appears to decrease since 1989.
authors.affiliation: Service d'Onco-Hématologie, Hôpital de Hautepierre.
authors.forename: R
authors.initials: R
authors.lastname: Herbrecht
authors.forename: J
authors.initials: J
authors.lastname: Waller
authors.forename: H
authors.initials: H
authors.lastname: Koenig
authors.forename: V
authors.initials: V
authors.lastname: Boussuge-Widehem
authors.forename: P
authors.initials: P
authors.lastname: Dufour
authors.forename: B
authors.initials: B
authors.lastname: Lioure
authors.forename: F
authors.initials: F
authors.lastname: Maloisel
mesh_terms: D000328:Adult; D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology* / Q000401:mortality; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
vernacular_title: Aspergilloses invasives chez les immunodéprimés. Analyse de 57 cas.