title: [Retinoblastoma].
abstract: Retinoblastoma (RB) is the most frequent ocular tumor in childhood. Due to recent advances in molecular biology, RB has become a study model for cancer suppressor genes, and antenatal diagnosis has now become feasible. The goals of therapy include an improved survival rate, decrease in iatrogenic sequelae (especially enucleation), and avoidance of radio-induced neoplasias. This review examines recent data from the literature.
authors.affiliation: Service de pédiatrie, centre L-Bérard, Lyon, France.
authors.forename: E
authors.initials: E
authors.lastname: Bouffet
authors.forename: D
authors.initials: D
authors.lastname: Frappaz
authors.forename: J D
authors.initials: JD
authors.lastname: Grange
authors.forename: P
authors.initials: P
authors.lastname: Romestaing
authors.forename: H
authors.initials: H
authors.lastname: Sobol
authors.forename: M
authors.initials: M
authors.lastname: Favrot
authors.forename: M
authors.initials: M
authors.lastname: Brunat-Mentigny
authors.forename: T
authors.initials: T
authors.lastname: Philip
mesh_terms: D002648:Child; D005134:Eye Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D006801:Humans; D012175:Retinoblastoma / Q000175:diagnosis / Q000235:genetics / Q000628:therapy
vernacular_title: Le rétinoblastome.