Opportunistic intraocular infections in AIDS.
In conclusion, this clinicopathologic study has shown that CMV ocular infection is present in about 16% of terminal AIDS patients. The treatment of CMV retinitis reduces the number of CMV-infected nonocular organs and may also lessen the severity and control the spread of concurrent nonocular infection, both of which may prolong survival in AIDS patients. Other opportunistic infections, involving primarily the choroid, were also seen in a number of patients, some of whom had concurrent intraocular infections with CMV and P carinii, M avium-intracellulare, C neoformans. In addition, all of these choroidal infections were components of disseminated infection, underscoring the increasingly important role of the ophthalmologist in the diagnosis and treatment of disseminated opportunistic infections in AIDS.
Morinelli
E N
EN
Pathology Laboratory, Doheny Eye Institute, University of Southern California School of Medicine, Los Angeles.
Dugel
P U
PU
Lee
M
M
Klatt
E C
EC
Rao
N A
NA
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002833:Choroiditis / Q000188:drug therapy / Q000473:pathology; D003586:Cytomegalovirus Infections / Q000188:drug therapy / Q000473:pathology*; D015828:Eye Infections, Viral / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D017245:Foscarnet / Q000627:therapeutic use; D015774:Ganciclovir / Q000627:therapeutic use; D015497:HIV-1; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012173:Retinitis / Q000188:drug therapy / Q000473:pathology
D017245:Foscarnet; D015774:Ganciclovir