title: Toxicity of French Polynesian strains of Gambierdiscus toxicus in cultures.
abstract: Seven clonal strains of Gambierdiscus toxicus isolated from three ciguateric areas around Tahiti island were mass cultured and extracted for ciguatoxins and maitotoxin. CTX analogs were detected only in one clone (GTP1), suggesting that CTX production may be strain-dependent. However, this in vitro production of CTXs, which remains fairly poor with regards to the toxicity levels encountered in wild G. toxicus, is not a stable temporal characteristic. On the other hand, maitotoxic compounds were detected in all 7 strains in copious amount, especially in clone GTH2.
authors.affiliation: Institut Territorial de Recherches Médicales Louis Malardé, Papeete, Tahiti, French Polynesia.
authors.forename: L
authors.initials: L
authors.lastname: Micouin
authors.forename: M
authors.initials: M
authors.lastname: Chinain
authors.forename: P
authors.initials: P
authors.lastname: Asin
authors.forename: A M
authors.initials: AM
authors.lastname: Legrand
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D002922:Ciguatoxins / Q000032:analysis / Q000096:biosynthesis* / Q000633:toxicity; D004141:Dinoflagellida / Q000378:metabolism*; D008387:Marine Toxins / Q000032:analysis / Q000096:biosynthesis* / Q000633:toxicity; D051379:Mice; D035964:Oxocins; D011114:Polynesia; D013045:Species Specificity; D000095702:Polyether Toxins
chemical_list: D002922:Ciguatoxins; D008387:Marine Toxins; D035964:Oxocins; C020394:maitotoxin; D000095702:Polyether Toxins