title: Myoepithelioma of the lacrimal gland: report of a case with spindle cell morphology.
abstract: The case is described of a 23-year-old female patient presenting with unilateral proptosis, headaches, and transient epiphora. Surgery revealed an encapsulated tumour composed exclusively of spindle-shaped cells within a richly vascularised myxoid stroma. Immunohistochemical staining showed focal positivity for smooth muscle actin, vimentin, and glial fibrillary acidic protein. These combined findings are interpreted as providing evidence of a myoepithelioma, which may be regarded as a monomorphic adenoma consisting solely of myoepithelial cells. To our knowledge this is only the second report of such a tumour in the lacrimal gland.
authors.affiliation: Department of Pathology, Institute of Ophthalmology, London.
authors.forename: R L
authors.initials: RL
authors.lastname: Font
authors.forename: A
authors.initials: A
authors.lastname: Garner
mesh_terms: D000199:Actins / Q000032:analysis; D000328:Adult; D005134:Eye Neoplasms / Q000737:chemistry / Q000473:pathology*; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D007765:Lacrimal Apparatus / Q000473:pathology*; D009208:Myoepithelioma / Q000737:chemistry / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D005904:Glial Fibrillary Acidic Protein; D014746:Vimentin