title: Hodgkin's disease and Epstein-Barr virus.
abstract: Seroepidemiological and molecular biological studies have established an association of Hodgkin's disease with Epstein-Barr virus (EBV). Recently, EBV genomes and gene products, most notably the latent membrane protein (LMP), have been detected in approximately 50% of the cases. The findings suggest that EBV may contribute to the pathoetiology of a sizable proportion of Hodgkin's disease cases.
authors.affiliation: Institute of Pathology, Free University Berlin, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Herbst
authors.forename: G
authors.initials: G
authors.lastname: Pallesen
authors.forename: L M
authors.initials: LM
authors.lastname: Weiss
authors.forename: G
authors.initials: G
authors.lastname: Delsol
authors.forename: R F
authors.initials: RF
authors.lastname: Jarrett
authors.forename: E
authors.initials: E
authors.lastname: Steinbrecher
authors.forename: H
authors.initials: H
authors.lastname: Stein
authors.forename: S
authors.initials: S
authors.lastname: Hamilton-Dutoit
authors.forename: P
authors.initials: P
authors.lastname: Brousset
mesh_terms: D015703:Antigens, CD / Q000235:genetics; D000951:Antigens, Neoplasm / Q000235:genetics; D000956:Antigens, Viral / Q000235:genetics; D015972:Gene Expression Regulation, Neoplastic / Q000235:genetics; D015967:Gene Expression Regulation, Viral / Q000235:genetics; D016679:Genome, Viral; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity*; D006689:Hodgkin Disease / Q000209:etiology / Q000235:genetics / Q000382:microbiology*; D006801:Humans; D017730:Ki-1 Antigen; D016403:Lymphoma, Large B-Cell, Diffuse / Q000235:genetics; D011379:Prognosis; D011506:Proteins / Q000235:genetics; D016601:RNA-Binding Proteins; D012269:Ribosomal Proteins
chemical_list: D015703:Antigens, CD; D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D017730:Ki-1 Antigen; D011506:Proteins; D016601:RNA-Binding Proteins; D012269:Ribosomal Proteins; C067169:RPL22 protein, human