title: [Primary disorders of neutrophils: principal clinical and laboratory aspects].
abstract: This article presents a review of different categories of inherited neutrophil dysfunctions, such as chronic granulomatous disease, disorders of chemotaxis, defects of degranulation and the leukocyte adherence deficiency. The clinical manifestations and laboratory findings of these phagocyte abnormalities, with particular reference to various tests of neutrophil functions used for diagnostic elucidation are described.
authors.affiliation: Seção de Imunologia, Instituto Adolfo Lutz, São Paulo.
authors.forename: R
authors.initials: R
authors.lastname: Bellinati-Pires
authors.forename: M I
authors.initials: MI
authors.lastname: Araújo
authors.forename: M M
authors.initials: MM
authors.lastname: Carneiro-Sampaio
mesh_terms: D015550:Cell Degranulation; D002609:Chediak-Higashi Syndrome / Q000209:etiology*; D002634:Chemotaxis, Leukocyte; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000209:etiology*; D006105:Granulomatous Disease, Chronic / Q000150:complications / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D006942:Hypergammaglobulinemia / Q000209:etiology*; D007073:Immunoglobulin E; D009504:Neutrophils / Q000378:metabolism / Q000502:physiology*
chemical_list: D007073:Immunoglobulin E
vernacular_title: Disfunções primárias de neutrófilos: principais aspectos clínicos e laboratoriais.