Central pontine myelinolysis as a manifestation of the paraneoplastic syndrome.
We have described a patient who had lung carcinoma, syndrome of inappropriate antidiuretic hormone, and central pontine myelinolysis (CPM). Although this association is well-known, it appears to be the first report having radiographic documentation of both the intracranial and intrathoracic abnormalities. When searching for the cause of CPM, the possibility of an underlying malignancy should also be considered. This may be more common than the radiology literature would suggest.
Hardjasudarma
M
M
Department of Radiology, Louisiana State University Medical Center, Shreveport 71130.
Husain
F
F
Fowler
M
M
Eisenberg
R L
RL
Mirfakhraee
M
M
D000328:Adult; D018288:Carcinoma, Small Cell / Q000150:complications / Q000000981:diagnostic imaging; D003711:Demyelinating Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D005260:Female; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000175:diagnosis / Q000209:etiology; D008175:Lung Neoplasms / Q000150:complications / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D010257:Paraneoplastic Syndromes / Q000175:diagnosis*; D011149:Pons / Q000000981:diagnostic imaging; D011859:Radiography