title: Inclusion body myositis: its relative frequency in elderly people.
abstract: Inclusion body myositis (IBM) is a distinct, steroid resistant, form of inflammatory myopathy. Its recognition is the more important because of the preponderant occurrence in the elderly, in whom steroid treatment is hazardous. Since the relative frequency of IBM among inflammatory myopathies in the elderly is undetermined, we retrospectively studied its frequency among all our patients over 50 years, diagnosed between 1980 and 1991 with inflammatory myopathy. Nine of 15 patients with inflammatory myopathy appeared to suffer from IBM. In a further 2 patients this diagnosis was strongly suspected. We conclude that IBM is the most frequent inflammatory myopathy in the elderly. This observation warrants restraint with steroids in the management of inflammatory myopathy in the elderly.
authors.affiliation: Department of Neurology, University Hospital, Leiden, The Netherlands.
authors.forename: M L
authors.initials: ML
authors.lastname: Maat-Schieman
authors.forename: J D
authors.initials: JD
authors.lastname: Macfarlane
authors.forename: G T
authors.initials: GT
authors.lastname: Bots
authors.forename: A R
authors.initials: AR
authors.lastname: Wintzen
mesh_terms: D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009220:Myositis / Q000473:pathology*