Prognostic importance of human papillomavirus type 16 DNA in cervical cancer.
Human papillomavirus (HPV) type 16 DNA is frequent in invasive cervical cancers. Among 43 patients with invasive cervical cancer, HPV-16-positive tumors spread to the parametrial and pelvic lymph nodes significantly more often than did HPV-16-negative tumors (P less than 0.05). Demonstration of HPV-16 DNA in invasive cervical cancers may be an additional prognostic factor for this disease.
Girardi
F
F
Department of Obstetrics and Gynecology, University of Graz, Austria.
Fuchs
P
P
Haas
J
J
D000328:Adult; D000368:Aged; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D027383:Papillomaviridae / Q000235:genetics*; D011379:Prognosis; D014412:Tumor Virus Infections / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000382:microbiology* / Q000473:pathology
D004279:DNA, Viral