title: Structure and function of the bc-complex of Rhodobacter sphaeroides.
abstract: The ubiquinol:cytochrome c2 oxidoreductase (bc-complex) of Rhodobacter sphaeroides has three main subunits, which bear the prosthetic groups, and contribute to three catalytic sites and internal electron transfer pathways which define the modified Q-cycle mechanism. In this paper, we report on progress in modelling the structure of the bc-complex, and experiments using site directed mutagenesis and biophysical assay to probe the structural and function consequences of specific modifications to these subunits.
authors.affiliation: Department of Physiology, University of Illinois, Urbana 61801.
authors.forename: A
authors.initials: A
authors.lastname: Crofts
authors.forename: B
authors.initials: B
authors.lastname: Hacker
authors.forename: B
authors.initials: B
authors.lastname: Barquera
authors.forename: C H
authors.initials: CH
authors.lastname: Yun
authors.forename: R
authors.initials: R
authors.lastname: Gennis
mesh_terms: D016227:Benzoquinones / Q000737:chemistry / Q000378:metabolism; D014450:Electron Transport Complex III / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D016297:Mutagenesis, Site-Directed; D012242:Rhodobacter sphaeroides / Q000201:enzymology*
chemical_list: D016227:Benzoquinones; C004532:quinone; D014450:Electron Transport Complex III