title: Orthotopic heart transplantation: an efficient treatment in a young boy with doxorubicin-induced cardiomyopathy.
abstract: We present the case of a boy who underwent orthotopic heart transplantation at the age of 14 years because of doxorubicin-induced cardiomyopathy 9 years after treatment of a Wilms tumor of the left kidney. Three years after heart transplantation the patient enjoys a normal daily life. Invasive studies show normal cardiac hemodynamic results and in spite of previous nephrectomy and long-term cyclosporine treatment, renal function is only slightly impaired. So far no secondary neoplasia has occurred under chronic immunosuppression.
authors.affiliation: Division of Cardiology, University Hospital, Zurich, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Lüthy
authors.forename: M
authors.initials: M
authors.lastname: Furrer
authors.forename: M
authors.initials: M
authors.lastname: Waser
authors.forename: M
authors.initials: M
authors.lastname: Maggiorini
authors.forename: H J
authors.initials: HJ
authors.lastname: Pluess
authors.forename: F
authors.initials: F
authors.lastname: Real
authors.forename: B
authors.initials: B
authors.lastname: Weiss
authors.forename: A
authors.initials: A
authors.lastname: Gallino
authors.forename: M
authors.initials: M
authors.lastname: Turina
mesh_terms: D000293:Adolescent; D002311:Cardiomyopathy, Dilated / Q000139:chemically induced* / Q000601:surgery; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000009:adverse effects* / Q000627:therapeutic use; D016027:Heart Transplantation; D006801:Humans; D007165:Immunosuppression Therapy; D007680:Kidney Neoplasms / Q000628:therapy; D008297:Male; D013997:Time Factors; D009396:Wilms Tumor / Q000628:therapy
chemical_list: D004317:Doxorubicin