title: OHIO-1 beta-lactamase resistant to mechanism-based inactivators.
authors.affiliation: Division of Infectious Diseases, Case Western Reserve University, Cleveland OH.
authors.forename: R A
authors.initials: RA
authors.lastname: Bonomo
authors.forename: C
authors.initials: C
authors.lastname: Currie-McCumber
authors.forename: D M
authors.initials: DM
authors.lastname: Shlaes
mesh_terms: D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001483:Base Sequence; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics; D010397:Penicillanic Acid / Q000494:pharmacology; D010957:Plasmids / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid; D013407:Sulbactam / Q000494:pharmacology; D000078142:Tazobactam; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D002969:Clavulanic Acids; D019818:Clavulanic Acid; D010397:Penicillanic Acid; C054882:beta-lactamase PIT-2; D001618:beta-Lactamases; D013407:Sulbactam; D000078142:Tazobactam