title: Hairy leukoplakia in an HIV-negative, nonimmunosuppressed patient.
abstract: Oral hairy leukoplakia is an Epstein-Barr virus-associated lesion that is considered to be a marker of immunosuppression. We report a case of oral hairy leukoplakia in a healthy nonimmunosuppressed elderly patient with no evidence of HIV infection on repeated investigation. This report has important implications on our understanding of the significance of this lesion.
authors.affiliation: Department of Oral Medicine and Oral Pathology, University of Edinburgh, Scotland.
authors.forename: D H
authors.initials: DH
authors.lastname: Felix
authors.forename: K
authors.initials: K
authors.lastname: Watret
authors.forename: D
authors.initials: D
authors.lastname: Wray
authors.forename: J C
authors.initials: JC
authors.lastname: Southam
mesh_terms: D000368:Aged; D004279:DNA, Viral / Q000032:analysis; D006679:HIV Seropositivity; D006566:Herpesviridae Infections / Q000276:immunology*; D004854:Herpesvirus 4, Human; D006801:Humans; D017403:In Situ Hybridization; D007972:Leukoplakia, Oral / Q000276:immunology* / Q000382:microbiology; D008213:Lymphocyte Activation; D008297:Male
chemical_list: D004279:DNA, Viral