title: [Congenital toxoplasmosis in the Alpes-Maritimes region. Apropos of 26 cases observed between 1984 and 1990].
abstract: Twenty-six cases of congenital toxoplasmosis observed in the department of Alpes Maritimes (Chief Town: Nice) between 1984 and 1990 are reported. All affected children were treated by pyrimethamine and sulfonamide as soon as the diagnosis was established. None of them exhibited serious sequellae. In most cases (58%) there were no clinical manifestations in agreement with other reports. Benign manifestations were observed in 10 cases (38%): 4 chorioretinitis; 4 intracranial calcifications: 1 febrile seizure; 7 hyperproteinorachias: 3 isolated and 4 associated with other signs. In 3 cases, secondary lesions appeared during the treatment period. This confirms the need for active therapeutic research in order to decrease the risk of late ocular complication which is the major problem of the disease.
authors.affiliation: Clinique pédiatrique, hôpital de Cimiez, Nice, France.
authors.forename: N
authors.initials: N
authors.lastname: Ferret
authors.forename: P
authors.initials: P
authors.lastname: Marty
authors.forename: C
authors.initials: C
authors.lastname: Tordjman
authors.forename: A
authors.initials: A
authors.lastname: Deville
authors.forename: C
authors.initials: C
authors.lastname: Tommasi
authors.forename: P
authors.initials: P
authors.lastname: Velin
authors.forename: R
authors.initials: R
authors.lastname: Mariani
authors.forename: Y
authors.initials: Y
authors.lastname: Le Fichoux
mesh_terms: D002648:Child; D002675:Child, Preschool; D004338:Drug Combinations; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D006801:Humans; D007223:Infant; D011739:Pyrimethamine / Q000008:administration & dosage; D012189:Retrospective Studies; D013449:Sulfonamides / Q000008:administration & dosage; D014125:Toxoplasmosis, Congenital / Q000145:classification / Q000188:drug therapy / Q000453:epidemiology*
chemical_list: D004338:Drug Combinations; D013449:Sulfonamides; D011739:Pyrimethamine
vernacular_title: La toxoplasmose congénitale dans les Alpes-Maritimes. A propos de 26 cas observés entre 1984 et 1990.