Study of the effect of the state of reparative regeneration of normal hemopoietic tissue on the leukemic process.
On the basis of the investigation of transplanted leukemia development in mice with induced reparative restoration of hemopoietic tissue, of the antileukemic activity of various components isolated from regenerating blood forming organs and of the underlying mechanisms of this action, it has been suggested that some growth regulator molecules in recovering hemopoietic tissue are a part of the natural antileukemic defence of the body and may be of special significance in leukemia treatment especially for residual leukemic cell inhibition as a strategy.
Svirnovski
A I
AI
Laboratory for Leukemia, Pathophysiology, Hematology and Blood Transfusion Institute, Ministry of Public Health of the Republic Belarus, Minsk.
D000818:Animals; D006410:Hematopoiesis / Q000502:physiology*; D007942:Leukemia, Experimental / Q000503:physiopathology*; D051379:Mice; D008806:Mice, Inbred AKR; D008810:Mice, Inbred C57BL; D009368:Neoplasm Transplantation; D012038:Regeneration