[Ouabain sensitivity of Na+,K+-ATPase in neuronal membranes].
Na+, K(+)-ATPase preparations of the rat and bovine brain and kidney were studied for ouabain sensitivity. Differences in apparent affinities to inhibitor of alpha(+)- and alpha-isozymes of Na+, K(+)-ATPase catalytic subunit were detected only in rat tissues but not in bovine ones. It is concluded that glycoside-sensitive and glycoside-resistant enzymic forms are not fully identical to alpha(+)- and alpha-subunit forms of Na+, K(+)-ATPase.
Kaplia
A A
AA
Kravtsov
A V
AV
D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000201:enzymology; D002417:Cattle; D002462:Cell Membrane / Q000187:drug effects / Q000201:enzymology; D007527:Isoenzymes / Q000187:drug effects; D007668:Kidney / Q000187:drug effects* / Q000201:enzymology; D009474:Neurons / Q000187:drug effects* / Q000201:enzymology; D010042:Ouabain / Q000494:pharmacology*; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors*; D013045:Species Specificity
D007527:Isoenzymes; D010042:Ouabain; D000254:Sodium-Potassium-Exchanging ATPase
Chuvstvitel'nost' Na+,K+-ATP-azy neĭronal'nykh membran k uabainu.