Purulent meningitis due to aspergillosis in a patient with systemic lupus erythematosus.
We report a 39-year-old female patient with systemic lupus erythematosus under immunosuppressive therapy who developed persistent neutrophilic meningitis, for which no infectious agent could be identified. Intensifying the immunosuppressive therapy induced a short amelioration of the clinical picture. At autopsy, basal meningitis was found to be due to Aspergillus sp.
Lammens
M
M
Department of Neuropathology, U.Z. Gasthuisberg, KUL, Leuven, Belgium.
Robberecht
W
W
Waer
M
M
Carton
H
H
Dom
R
R
D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis* / Q000473:pathology; D001230:Aspergillus / Q000648:ultrastructure; D001921:Brain / Q000473:pathology; D002544:Cerebral Infarction / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D016921:Meningitis, Fungal / Q000175:diagnosis* / Q000473:pathology; D009460:Neurologic Examination; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000473:pathology; D011559:Pseudotumor Cerebri / Q000175:diagnosis / Q000473:pathology; D014057:Tomography, X-Ray Computed