title: Effect of Pre-S1 protein on the long-term cultures of human lymphocytes after hepatitis B immunization.
abstract: Long-term cultured T-cells, reactive to Pre-S1 protein, were developed from peripheral blood mononuclear cells (PBMC) of individuals after recovery from hepatitis B infection and of vaccine recipients by in vitro Pre-S1 protein stimulation in the presence of IL-2. The proliferative responses to Pre-S1 protein and functional activities of cultured T-cells were characterized.
authors.affiliation: Microbiology and Virology Center, Polish Academy of Sciences, Lódź.
authors.forename: Z
authors.initials: Z
authors.lastname: Sułowska
authors.forename: H
authors.initials: H
authors.lastname: Tchórzewski
authors.forename: M
authors.initials: M
authors.lastname: Sidorkiewicz
authors.forename: A
authors.initials: A
authors.lastname: Płucienniczak
mesh_terms: D002478:Cells, Cultured; D006509:Hepatitis B / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D017325:Hepatitis B Vaccines / Q000276:immunology; D006801:Humans; D007114:Immunization; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D010835:Phytohemagglutinins / Q000494:pharmacology; D011498:Protein Precursors / Q000276:immunology*; D014614:Vaccines, Synthetic / Q000276:immunology
chemical_list: C075654:Engerix-B; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines; D010835:Phytohemagglutinins; D011498:Protein Precursors; D014614:Vaccines, Synthetic; C028784:phytohemagglutinin-P; C050806:presurface protein 1, hepatitis B surface antigen