[The rapid differential diagnosis of bacterial and viral meningitis by using the lysozyme test].
The authors have modified the technique of the lysozyme test by adding polimixin M sulfate into the gel bacterial medium. Rapid diagnosis with the use of this test is based on different time of the appearance of the lysis areas: in bacterial meningitides the CSF lysozyme activity is detectable within 15-120 min, whereas in viral meningitides it manifests 40-50 min later or does not manifest at all. The results were found to depend on the time of the CSF collection: the earlier the CSF samples were obtained, the higher was the share of positive results.
Babich
E M
EM
Derkach
S A
SA
Vasil'eva
I B
IB
Eliseeva
I V
IV
Makarenko
K K
KK
Valiukh
S V
SV
D004796:Clinical Enzyme Tests / Q000379:methods*; D003937:Diagnosis, Differential; D005782:Gels; D006801:Humans; D016920:Meningitis, Bacterial / Q000175:diagnosis*; D008587:Meningitis, Viral / Q000175:diagnosis*; D009113:Muramidase / Q000134:cerebrospinal fluid*; D011113:Polymyxins; D013997:Time Factors
D005782:Gels; D011113:Polymyxins; D009113:Muramidase
Differentsial'naia ékspress-diagnotika bakterial'nykh i virusnykh meningitov s pomoshch'iu lizotsimnogo testa.