[The individual characteristics of the postradiation reaction of the cyclic nucleotides in rat thymocytes].
It was shown that X-irradiation of rats (4.3 Gy), which were preliminarily divided into two groups by the neutrophilic reaction in the peripheral blood to the effect of a three-hour immobilization, induced different reactions of the cyclic nucleotide system. Thus, in animals hyper-reactive to stress radiation injury to the above system was severe: relative reactivity made 22.8% of the initial value, and adenylate cyclase ability to respond to a hormonal stimulus was drastically inhibited. In hyporeactive animals, relative reactivity of adenylate cyclase system after irradiation made 47% throughout the same period of observation; inhibition of adenylate cyclase activity was also less pronounced.
Lozinskaia
I N
IN
Nikiforova
N A
NA
Moskalenko
I P
IP
D000262:Adenylyl Cyclases / Q000032:analysis / Q000528:radiation effects; D000818:Animals; D000242:Cyclic AMP / Q000032:analysis / Q000528:radiation effects*; D006152:Cyclic GMP / Q000032:analysis / Q000528:radiation effects*; D008297:Male; D011836:Radiation Tolerance; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000097:blood; D013950:Thymus Gland / Q000737:chemistry / Q000378:metabolism / Q000528:radiation effects*; D013997:Time Factors
D000242:Cyclic AMP; D000262:Adenylyl Cyclases; D006152:Cyclic GMP
Individual'nye osobennosti postradiatsionnoĭ reaktsii tsiklicheskikh nukleotidov timotsitov krys.