Massive haemorrhage from rupture of a pancreatic pseudocyst after pentamidine-associated pancreatitis.
A 40 year-old man with the acquired immunodeficiency syndrome who was treated with intravenous pentamidine suffered a massive spontaneous haemorrhage caused by rupture of a pancreatic pseudocyst after pentamidine-induced pancreatitis. The patient previously presented symptomatic hypoglycaemia, severe nephrotoxicity and hyperkalaemia, while not receiving any other drug but pentamidine. This is the first case reported of such a complication of pentamidine induced pancreatitis, and one of the few cases reported of the latter adverse event.
Pais
J R
JR
Department of Internal Medicine, Hospital Ramon y Cajal, Madrid, Spain.
Cazorla
C
C
Novo
E
E
Viana
A
A
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000328:Adult; D017809:Fatal Outcome; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D008297:Male; D010192:Pancreatic Pseudocyst / Q000150:complications*; D010195:Pancreatitis / Q000139:chemically induced* / Q000150:complications*; D010419:Pentamidine / Q000009:adverse effects* / Q000627:therapeutic use; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy; D012422:Rupture, Spontaneous
D010419:Pentamidine