title: 5' avian leukosis virus sequences and osteopetrotic potential.
abstract: Recombinants of Rous-associated virus-0 and Br21 have been used to localize 5' viral sequences that affect the osteopetrotic potential of avian leukosis viruses. Rous-associated virus-0 is a benign subgroup E virus of endogenous origin that does not cause osteopetrosis. Br21 is a constructed subgroup E virus with high osteopetrotic potential. 5' sequences that affected osteopetrotic potential resided in an 834-bp region near the 5' LTR. Sequence analysis of this region revealed differences between Br21 and RAV-0 in the mRNA leader and codons for MA.
authors.affiliation: Department of Pathology, University of Massachusetts Medical Center, Worcester 01655.
authors.forename: H L
authors.initials: HL
authors.lastname: Robinson
authors.forename: R G
authors.initials: RG
authors.lastname: Foster
authors.forename: B P
authors.initials: BP
authors.lastname: Blais
authors.forename: S S
authors.initials: SS
authors.lastname: Reinsch
authors.forename: M
authors.initials: M
authors.lastname: Newstein
authors.forename: P R
authors.initials: PR
authors.lastname: Shank
mesh_terms: D000818:Animals; D001354:Avian Leukosis Virus / Q000235:genetics* / Q000472:pathogenicity; D001483:Base Sequence; D002645:Chickens; D003001:Cloning, Molecular; D003062:Codon / Q000235:genetics; D004279:DNA, Viral / Q000235:genetics*; D008969:Molecular Sequence Data; D010022:Osteopetrosis / Q000382:microbiology*; D010957:Plasmids / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics; D011995:Recombination, Genetic / Q000235:genetics; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics; D015183:Restriction Mapping
chemical_list: D003062:Codon; D004279:DNA, Viral; D012333:RNA, Messenger