title: Granulosa-theca cell tumor associated with an ovulation fossa and normal ovarian stroma in a mare.
abstract: A granulosa-theca cell tumor was found in an ovary that had an ovulation fossa and normal ovarian tissue. The ovary was removed from a mare with a history of ovarian enlargement and behavioral changes. The affected ovary had a multicystic appearance on ultrasonographic examination performed before surgery, and an ovulation fossa was not palpable on examination per rectum. However, during surgery, the affected ovary was found to be within normal size limits, with an enlargement on 1 pole, and to contain an ovulation fossa. Atrophy of the infundibulum of the affected ovary helped to confirm the diagnosis of granulosa-theca cell tumor, and the ovary was removed. The mare's testosterone concentrations were normal. Granulosa-theca cell tumors are usually associated with a spherical ovary, attributable to ablation of the ovulation fossa, with no normal ovarian tissue present.
authors.affiliation: Department of Medicine, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536.
authors.forename: K
authors.initials: K
authors.lastname: Hinrichs
authors.forename: S L
authors.initials: SL
authors.lastname: Cochran
authors.forename: S H
authors.initials: SH
authors.lastname: Schelling
authors.forename: R R
authors.initials: RR
authors.lastname: Steckel
mesh_terms: D000818:Animals; D005260:Female; D006106:Granulosa Cell Tumor / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D006734:Horse Diseases / Q000473:pathology* / Q000601:surgery; D006736:Horses; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D010053:Ovary / Q000473:pathology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D013798:Thecoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary*