title: [The study of Chinese herbal medicinal prescription with enzyme inhibitory activity. VI. The study of makyo-kanseki-to with adenosine 3',5'-cyclic monophosphate phosphodiesterase].
abstract: A Chinese herbal medicinal prescription, Makyo-kanseki-to, was studied for the inhibitory activity of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. The effect for the inhibitory activity of cAMP phosphodiesterase by combination with constituent crude drugs of the prescription was studied. Gypsum acted as a mitigatory component for Ephedra herb and Glycyrrhiza in cAMP phosphodiesterase inhibition test.
authors.affiliation: Toho University, School of Pharmaceutical, Chiba, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nikaido
authors.forename: S
authors.initials: S
authors.lastname: Iizuka
authors.forename: N
authors.initials: N
authors.lastname: Okada
authors.forename: T
authors.initials: T
authors.lastname: Kuge
authors.forename: T
authors.initials: T
authors.lastname: Ohmoto
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors*; D004339:Drug Compounding; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*
chemical_list: D004365:Drugs, Chinese Herbal; D015105:3',5'-Cyclic-AMP Phosphodiesterases