[Changes in serum endogenous digitalis-like factor concentration in patients with renal impairment].
Measurement of serum endogenous digitalis-like factor (EDF) concentration was carried out in 58 patients with renal impairment with radioimmunoassay. The results showed that serum EDF concentration in patients with renal impairment was markedly higher than that of normal cases. The serum EDF concentration was significantly elevated with decrease of renal function and was positively correlated with the levels of BUN and blood creatinine. The serum EDF concentration in patients with primary and secondary renal impairment was of no difference. It was found that the difference between patients with and without hypertension was statistically significant. The serum EDF concentrations were markedly decreased after hemodialysis but still higher than those of normal cases.
Ke
Y S
YS
Department of Medicine, Yijishan Hospital, Wannan Medical College, Anhui.
Tao
Y Y
YY
Yang
S Y
SY
D000328:Adult; D000368:Aged; D001798:Blood Proteins / Q000378:metabolism*; D001806:Blood Urea Nitrogen; D002298:Cardenolides; D003404:Creatinine / Q000097:blood; D004077:Digoxin; D005260:Female; D005921:Glomerulonephritis / Q000097:blood; D006801:Humans; D007674:Kidney Diseases / Q000097:blood* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012503:Saponins; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors / Q000097:blood
D001798:Blood Proteins; D002298:Cardenolides; D012503:Saponins; C034504:digoxin-like factors; D004077:Digoxin; D003404:Creatinine; D000254:Sodium-Potassium-Exchanging ATPase