title: [Neoplasms during the 1st year of life: a study of 116 cases treated during the last 10 years].
abstract: 116 infants under one year of age (14 per 100) with malignancies including 35 neuroblastomas, 23 retinoblastomas, 14 Wilm's tumours, 10 hepatoblastomas, 10 brain tumours, 9 germ cell tumours, 8 histiocytic and 7 soft tissue sarcomas, were treated in the last ten years. Hepatoblastoma is the highest relative incidence tumor in the first year of life and with brain tumours has the worst prognosis (50 and 40 per 100, respectively). The disease-free survival rate is most than 80 per 100 in neuro and nephroblastoma with medical and surgical treatment. Familiar incidence in Wilm's tumor is 42 per 100 and chemotherapy side effects are 23 per 100. Familiar incidence in neuroblastoma is 20 per 100 and chemotherapy side effects 21 per 100. In conclusion, in children with malignancies under one year of age have good prognosis (75 per 100 survival at five years), with lower surgical complications rate. Early diagnosis and response to chemotherapy, the side effects of which are considerable and should be strictly controlled, are key factors in the better prognosis and increased life expectancy in this group of patients.
authors.affiliation: Departamento de Cirugía Pediátrica, Hospital Materno-Infantil Valle de Hebrón, Barcelona.
authors.forename: V
authors.initials: V
authors.lastname: Martínez Ibáñez
authors.forename: A
authors.initials: A
authors.lastname: Pérez Martínez
authors.forename: A
authors.initials: A
authors.lastname: Marqués Gubern
authors.forename: J
authors.initials: J
authors.lastname: Lloret Roca
authors.forename: J
authors.initials: J
authors.lastname: Sánchez de Toledo
authors.forename: P
authors.initials: P
authors.lastname: Pérez Lacasta
authors.forename: M
authors.initials: M
authors.lastname: Escarre Jaume
authors.forename: L
authors.initials: L
authors.lastname: Roset Sánchez
authors.forename: R
authors.initials: R
authors.lastname: Pons Rodríguez
mesh_terms: D000367:Age Factors; D001932:Brain Neoplasms / Q000453:epidemiology; D006528:Carcinoma, Hepatocellular / Q000453:epidemiology; D015331:Cohort Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007680:Kidney Neoplasms / Q000453:epidemiology; D008113:Liver Neoplasms / Q000453:epidemiology; D009369:Neoplasms / Q000453:epidemiology*; D009447:Neuroblastoma / Q000453:epidemiology; D011379:Prognosis; D012175:Retinoblastoma / Q000453:epidemiology; D012509:Sarcoma / Q000453:epidemiology; D012983:Soft Tissue Neoplasms / Q000453:epidemiology; D013030:Spain / Q000453:epidemiology; D009396:Wilms Tumor / Q000453:epidemiology
vernacular_title: Neoplasias en el primer año de la vida: estudio de 116 casos tratados en los ultimos diez años.