Rapid progression of HIV-1 infection to AIDS.
Homosexually acquired human immunodeficiency virus type 1 infection is usually slowly progressive, and reports of its rapid progression to acquired immunodeficiency syndrome are rare. We present a case of acute human immunodeficiency virus type 1 and cytomegalovirus coinfection that progressed to acquired immunodeficiency syndrome and death in 7 months. The factors that determine the clinical outcome of human immunodeficiency virus type 1 infection are poorly defined; however, coinfection with other agents, such as cytomegalovirus, may influence its natural history.
Walsh
M B
MB
Department of Rheumatic and Immunologic Disease, Cleveland Clinic Foundation, OH 44195.
Calabrese
L H
LH
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000276:immunology; D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis / Q000276:immunology*; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D016516:CD4-CD8 Ratio; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000276:immunology; D005500:Follow-Up Studies; D015483:HIV Antibodies / Q000032:analysis; D006679:HIV Seropositivity / Q000175:diagnosis / Q000276:immunology*; D015497:HIV-1 / Q000276:immunology* / Q000472:pathogenicity; D006801:Humans; D008297:Male; D014775:Virus Activation / Q000276:immunology
D000914:Antibodies, Viral; D015483:HIV Antibodies