[Outcome of gestation of 32 pregnant women with toxoplasma and cytomegalovirus infection].
In an attempt to investigate the harmful effects of the infection of Toxoplasma and associated with cytomegalovirus on the fetus infection acquired transplacentally during their mothers' pregnancy sera from 1000 pregnant women were tested for antibodies to both pathogens and the circulating antigen of Toxoplasma by using ELISA. The test was positive (titre > or = 1:60400) in 32 of 1000 cases. Judging from the sero-positive results together with the case history, clinical manifestations and B-scan results, the 32 cases were advised to end their pregnancy. Necropsy and pathological examinations of the foetuses revealed stillborn foetus, hydrocephalus, acephalus, pleural effusion, ascites and other congenital malformations. Toxoplasma gondii were found in the tissues of 21 fetuses.
Pan
C W
CW
Wenzhou Medical College, Zhejiang.
Lin
F G
FG
Zhang
Z Y
ZY
Liu
Q Z
QZ
D000328:Adult; D000913:Antibodies, Protozoan / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D000953:Antigens, Protozoan / Q000097:blood; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000276:immunology; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology; D015597:Pregnancy Complications, Parasitic / Q000276:immunology; D011256:Pregnancy Outcome; D014123:Toxoplasmosis / Q000150:complications* / Q000276:immunology
D000913:Antibodies, Protozoan; D000914:Antibodies, Viral; D000953:Antigens, Protozoan