Opioid-binding cell adhesion molecule (OBCAM)-related clones from a rat brain cDNA library.
A rat brain cDNA library was screened with probes constructed from portions of the cDNA (OBCAM) encoding the opioid-binding cell adhesion molecule (OBCAM). Three clones of interest were isolated and sequenced. The largest clone, DUZ1, had a putative open reading frame (ORF) essentially identical to OBCAM in its C-terminal 318 amino acids (aa), but differing in its N-terminal aa (20 vs. 27 in OBCAM), and in all of its 5'-noncoding regions. The other clones, SG8 and SG13, had a putative ORF essentially identical to that of OBCAM, but differed from each other in a portion of their 5'-noncoding region. This study suggests that there is a family of OBCAM-like genes.
Lippman
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DA
Department of Pharmacology, University of Minnesota Medical School, Minneapolis 55455.
Lee
N M
NM
Loh
H H
HH
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D015723:Gene Library; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics*; D051381:Rats; D011957:Receptors, Opioid / Q000737:chemistry / Q000235:genetics*; D017465:Receptors, Opioid, delta
D011957:Receptors, Opioid; D017465:Receptors, Opioid, delta; D004247:DNA