title: Wheat-bran and oat-bran supplements' effects on blood lipids and lipoproteins.
abstract: To compare the effects of oat-bran fiber on blood lipids, we studied 84 healthy middle-aged men and women who were placed on metabolic diets, for 2 wk, that were supplemented with either wheat bran (n = 42) or oat bran (n = 42). Fiber supplementation was 1.6 micrograms dietary fiber/J (6.8 g dietary fiber/1000 kcal) to a maximum of 16.4 g fiber/d. Significantly greater decrease with oat than with wheat were seen in total cholesterol (0.56 +/- 0.08 mmol/L and 0.29 +/- 0.08 mmol/L, P = 0.022) and low-density-lipoprotein cholesterol (0.39 +/- 0.07 mmol/L and 0.15 +/- 0.07 mmol/L, P = 0.024). No significant differences were seen in high-density lipoprotein, apolipoproteins A-1 and B, or triglyceride. We conclude that oat bran has an advantage over wheat bran in lowering serum lipids when tested in metabolic diets on large numbers of individuals with an initial mean serum cholesterol concentration above the desirable range, at 5.61 +/- 0.16 mmol/L.
authors.affiliation: Department of Surgery, Mount-Sinai Hospital, Toronto, Canada.
authors.forename: H
authors.initials: H
authors.lastname: Kashtan
authors.forename: H S
authors.initials: HS
authors.lastname: Stern
authors.forename: D J
authors.initials: DJ
authors.lastname: Jenkins
authors.forename: A L
authors.initials: AL
authors.lastname: Jenkins
authors.forename: K
authors.initials: K
authors.lastname: Hay
authors.forename: N
authors.initials: N
authors.lastname: Marcon
authors.forename: S
authors.initials: S
authors.lastname: Minkin
authors.forename: W R
authors.initials: WR
authors.lastname: Bruce
mesh_terms: D000328:Adult; D000368:Aged; D001835:Body Weight; D002318:Cardiovascular Diseases / Q000517:prevention & control; D002784:Cholesterol / Q000097:blood; D003110:Colonic Neoplasms / Q000601:surgery; D004043:Dietary Fiber / Q000008:administration & dosage*; D004311:Double-Blind Method; D002523:Edible Grain; D005260:Female; D005527:Food, Fortified; D006801:Humans; D007417:Intestinal Polyps / Q000601:surgery; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
chemical_list: D004043:Dietary Fiber; D008055:Lipids; D008074:Lipoproteins; D002784:Cholesterol