Behavioral conditioned responses to contextual and odor stimuli paired with LiCl administration.
The present experiments examined whether behavioral conditioned responses (CRs) develop to LiCl-paired contextual and odor stimuli, and whether these CRs are similar to the behaviors observed following the administration of the drug. During conditioning, a novel context (Experiment 1) or a novel odor (Experiment 2) was paired with LiCl injections, and the CRs which developed to these stimuli were assessed during testing. Suppression of general activity occurred after LiCl exposure and after exposure to the lithium-paired context and odor. However, the actual behaviors which emerged as conditioned responses were distinctly different from those which were elicited by the drug itself. Lying on belly was the predominant unconditioned response to LiCl. Freezing was the predominant CR to the context, whereas gaping was the predominant CR to the odor. These outcomes are discussed and compared to previous results using a taste stimulus.
Meachum
C L
CL
Department of Psychology, University of Washington, Seattle 98195.
Bernstein
I L
IL
D000818:Animals; D002712:Chlorides / Q000494:pharmacology*; D003214:Conditioning, Classical / Q000187:drug effects*; D003463:Cues; D006120:Grooming / Q000187:drug effects; D008094:Lithium / Q000494:pharmacology*; D018021:Lithium Chloride; D008297:Male; D009812:Odorants; D051381:Rats
D002712:Chlorides; D008094:Lithium; D018021:Lithium Chloride