title: [The rapid differential diagnosis of bacterial and viral meningitis by using the lysozyme test].
abstract: The authors have modified the technique of the lysozyme test by adding polimixin M sulfate into the gel bacterial medium. Rapid diagnosis with the use of this test is based on different time of the appearance of the lysis areas: in bacterial meningitides the CSF lysozyme activity is detectable within 15-120 min, whereas in viral meningitides it manifests 40-50 min later or does not manifest at all. The results were found to depend on the time of the CSF collection: the earlier the CSF samples were obtained, the higher was the share of positive results.
authors.forename: E M
authors.initials: EM
authors.lastname: Babich
authors.forename: S A
authors.initials: SA
authors.lastname: Derkach
authors.forename: I B
authors.initials: IB
authors.lastname: Vasil'eva
authors.forename: I V
authors.initials: IV
authors.lastname: Eliseeva
authors.forename: K K
authors.initials: KK
authors.lastname: Makarenko
authors.forename: S V
authors.initials: SV
authors.lastname: Valiukh
mesh_terms: D004796:Clinical Enzyme Tests / Q000379:methods*; D003937:Diagnosis, Differential; D005782:Gels; D006801:Humans; D016920:Meningitis, Bacterial / Q000175:diagnosis*; D008587:Meningitis, Viral / Q000175:diagnosis*; D009113:Muramidase / Q000134:cerebrospinal fluid*; D011113:Polymyxins; D013997:Time Factors
chemical_list: D005782:Gels; D011113:Polymyxins; D009113:Muramidase
vernacular_title: Differentsial'naia ékspress-diagnotika bakterial'nykh i virusnykh meningitov s pomoshch'iu lizotsimnogo testa.