[Syndromes of venous mesenteric ischemia: infarction and transient ischemia].
The reports of 8 patients with acute or subacute abdominal pain related to venous mesenteric ischemia were reviewed. None of the patients presented local or regional predisposing factors for venous thrombosis. In 4 patients, a localized segment of ischemic small bowel (median length 125 cm; range: 30-350) was resected without immediate anastomosis and postoperative anticoagulation therapy was given. Two of these patients developed recurrent ischemia involving the bowel adjacent to the stoma, treated successfully in 1 case by a repeat resection. The 4 other patients hospitalized with intestinal obstructive symptoms (1 case) or abdominal angina (3 cases) were treated by long term anticoagulation in 3 cases and artificial nutrition in 2 cases. None of them developed mesenteric infarction with a median follow up of 34 months. In 7 of the 8 patients, a coagulopathy was found: primary myeloproliferative disorder (1 case), hypercoagulation state (5 cases), autoimmune hemolytic anemia (1 case). These observations suggest that venous mesenteric ischemia included two different entities on the basis of clinical and morphological criteria: mesenteric infarction and subacute transient ischemia without bowel infarction. Most of apparently idiopathic cases of acute or subacute venous mesenteric ischemia are related to hypercoagulation states requiring a long term anticoagulation.
Cardot
F
F
Groupe de Biochimie et Physiopathologie Digestive et Nutritionnelle, Hôpital Charles-Nicolle, Rouen.
Borg
J Y
JY
Guédon
C
C
Lerebours
E
E
Colin
R
R
D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D007238:Infarction / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D007421:Intestine, Small / Q000098:blood supply / Q000601:surgery; D007511:Ischemia / Q000150:complications*; D008297:Male; D008641:Mesenteric Vascular Occlusion / Q000150:complications*; D008642:Mesenteric Veins / Q000503:physiopathology; D008643:Mesentery / Q000098:blood supply*; D008875:Middle Aged; D011169:Portal Vein / Q000503:physiopathology; D012008:Recurrence; D012189:Retrospective Studies; D013577:Syndrome; D013927:Thrombosis / Q000150:complications* / Q000188:drug therapy
D006495:Heparin, Low-Molecular-Weight
Les syndromes d'ischémie veineuse mésentérique: infarctus et ischémie transitoire.