["Wrapping therapy" for advanced hepatic cancer with arterial and intraportal infusion chemotherapy].
A new treatment method to intercept collaterals using silicone rubber sheeting was used for 5 patients with advanced hepatic cancer. The therapy was carried out to prevent new collaterals. This procedure was followed by arterial chemoembolization, arterial infusion chemotherapy and intraportal infusion chemotherapy. The results were complete response in 2 patients, partial response in 2 patients, and no change in 1 patient. The overall survival time was 7-54 months after wrapping. Although a randomized control study is necessary to assess the true value of this method, the new therapy is considered worth using as an adjuvant treatment for advanced hepatic malignancies uncontrolled by arterial chemotherapy or chemoembolization.
Iwamoto
S
S
Dept. of Surgery, Center for Adult Diseases, Osaka.
Sasaki
Y
Y
Imaoka
S
S
Masutani
S
S
Ohashi
I
I
Ishikawa
O
O
Oohigasi
H
H
Furukawa
H
H
Hiratsuka
M
M
Kameyama
M
M
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000379:methods*; D003097:Collateral Circulation; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial; D007459:Iodized Oil / Q000008:administration & dosage; D008102:Liver Circulation; D008113:Liver Neoplasms / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011168:Portal System; D012826:Silicone Elastomers; D015996:Survival Rate
D000970:Antineoplastic Agents; D012826:Silicone Elastomers; D007459:Iodized Oil