title: [Clinical significance of the use-dependent sodium channel block and reverse use-dependent potassium channel block of class I and class III antiarrhythmic agents and their values to predict drug efficacy].
authors.affiliation: Department of Medicine, Keio University, School of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Sadanaga
authors.forename: S
authors.initials: S
authors.lastname: Ogawa
authors.forename: Y
authors.initials: Y
authors.lastname: Okada
authors.forename: S
authors.initials: S
authors.lastname: Handa
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy* / Q000503:physiopathology; D004206:Disopyramide / Q000627:therapeutic use; D004341:Drug Evaluation; D015716:Electrocardiography, Ambulatory; D004594:Electrophysiology; D005080:Exercise Test; D006801:Humans; D008012:Lidocaine / Q000031:analogs & derivatives / Q000627:therapeutic use; D008801:Mexiletine / Q000627:therapeutic use; D008875:Middle Aged; D015221:Potassium Channels / Q000187:drug effects*; D015222:Sodium Channels / Q000187:drug effects*
chemical_list: D000889:Anti-Arrhythmia Agents; D015221:Potassium Channels; D015222:Sodium Channels; D008801:Mexiletine; D008012:Lidocaine; C042288:pilsicainide; D004206:Disopyramide