The effect of feeding on plasma immunoreactive ACTH and beta-endorphin levels in newborn infant.
In order to clarify whether an interaction between endogenous opioids and feeding occurs at birth, we studied Beta-endorphin (beta-EP) and ACTH plasma levels in response to a feed of 10% glucose, or formula, in 120 healthy full-term infants. Neither postprandial beta-EP nor ACTH increases were found at the 24th hour or on the fourth day of life. beta-EP physiology in newborn infants seems to be different from adults.
Gemelli
M
M
Institute of Clinica Pediatrica, University of Messina, Italy.
Manganaro
R
R
De Luca
F
F
Imperatore
C
C
Costa
G
G
Mamì
C
C
D000324:Adrenocorticotropic Hormone / Q000097:blood*; D004435:Eating / Q000502:physiology*; D005947:Glucose / Q000494:pharmacology; D006801:Humans; D007225:Infant Food; D007231:Infant, Newborn; D011863:Radioimmunoassay; D001615:beta-Endorphin / Q000097:blood*
D001615:beta-Endorphin; D000324:Adrenocorticotropic Hormone; D005947:Glucose