title: Myospherulosis in the operated temporal bone.
abstract: Myospherulosis is an unusual foreign-body reaction occurring in tissues exposed to petrolatum-based products. Histopathologically this disorder is characterized by the presence of large and small tissue spaces containing amorphous debris and peculiar sac-like structures enclosing numerous brown spherical bodies. A rare case of myospherulosis of the middle ear and mastoid is presented and the literature is reviewed.
authors.affiliation: Department of Otorhinolaryngology, Academic Hospital Nijmegen, The Netherlands.
authors.forename: J J
authors.initials: JJ
authors.lastname: Manni
authors.forename: H E
authors.initials: HE
authors.lastname: Schaafsma
authors.forename: P P
authors.initials: PP
authors.lastname: Vennix
mesh_terms: D000328:Adult; D005549:Foreign-Body Reaction / Q000473:pathology* / Q000601:surgery; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D007809:Lanolin / Q000009:adverse effects; D008297:Male; D008416:Mastoid / Q000601:surgery; D010034:Otitis Media with Effusion / Q000473:pathology* / Q000601:surgery; D010577:Petrolatum / Q000009:adverse effects; D011183:Postoperative Complications / Q000473:pathology* / Q000601:surgery; D012008:Recurrence; D013701:Temporal Bone / Q000473:pathology / Q000601:surgery*
chemical_list: D007809:Lanolin; D010577:Petrolatum