[Malignant fibrous histiocytoma with giant cells of the skin. Anatomoclinical and immunohistochemical study of a case].
The authors report a case of malignant giant cell soft tissue tumor which appeared as a skin tumor of the thigh in a Tunisian women aged 17 years. Immunohistochemical study showed that the giant cells recognized KP1 antibody, while spindle interstitial cells reacted with anti-factor XIIIa antibody. The patient is alive and well eighteen months after large surgical removal. Two similar cases have been reported in the literature. Differential diagnosis, histogenesis and prognosis of this rare tumor are discussed.
Bouziani
A
A
Service d'Anotomie et de Cytologie Pathologiques, Hôpital Militaire Habib Thameur, Tunis, Tunisie.
Ben Ayed
M
M
Kamoun
N
N
Zermani
R
R
Marrak
H
H
Hajri
S
S
De Saint-Maur
P
P
D000293:Adolescent; D005260:Female; D005870:Giant Cell Tumors / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery
Histiocytome fibreux malin à cellules géantes de siège cutané. Etude anatomoclinique et immunohistochimique d'une observation.