[ACTH-independent Cushing's syndrome due to bilateral macronodular adrenal hyperplasia with empty sella turcica and anterior panhypopituitarism].
A case is presented of Cushing's syndrome due to macronodular bilateral adrenal hyperplasia which is ACTH-independent as was demonstrated by the undetectable basal and after stimulation with metoprolol ACTH plasma levels. High cortisol levels is associated in this patient with empty sella turcica and anterior panhypopituitarism with confirm the exclusive adrenal origin of the hormone hypersecretion and the lack of treatment success with hypophysis ablation in this process.
Menéndez Torre
E L
EL
Servicio de Endocrinología, Hospital de Navarra, Pamplona.
López Carballo
M T
MT
Rodríguez Erdozain
R
R
Urbieta Echezarreta
M
M
Lafita Tejedor
J
J
Forga Llenas
L
L
D000311:Adrenal Glands / Q000473:pathology*; D000324:Adrenocorticotropic Hormone / Q000097:blood*; D000368:Aged; D003480:Cushing Syndrome / Q000097:blood / Q000175:diagnosis*; D004652:Empty Sella Syndrome / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D006964:Hyperpituitarism / Q000097:blood / Q000175:diagnosis*; D006965:Hyperplasia / Q000097:blood / Q000175:diagnosis; D008797:Metyrapone; D010903:Pituitary Gland, Anterior
D000324:Adrenocorticotropic Hormone; D008797:Metyrapone
Síndrome de Cushing ACTH-independiente por hiperplasia adrenal macronodular bilateral con silla turca vacía y panhipopituitarismo anterior.