[A case-control study of colorectal cancer in Beijing].
A case-control study was conducted among 250 persons suffering from cancer of the colon and rectum (CRC) in the urban area of Beijing from Jan 1, 1988-June 30, 1989 to explore the risk factors for CRC. 500 neighbour residents were matched as control. The chi-square test and conditional logistic Regression analysis show that high consumption of meat, oil, low occupational physical activity and psychological stress were risk factors of CRC. A trend of increased odds ratio (OR) of CRC with high meat intake and a trend of decreased OR with increased occupational physical activity were found. The high consumption of vegetables and the habit of eating uncooked fresh vegetables showed a protective effect on CRC. The results of the study support the CRC etiological hypotheses of "fat-bile acid action" and "deficiency of dietary fibres".
Zhang
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Dept. of Epidemiology, Beijing Medical University.
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D003110:Colonic Neoplasms / Q000453:epidemiology* / Q000209:etiology; D004041:Dietary Fats / Q000008:administration & dosage; D004043:Dietary Fiber / Q000008:administration & dosage; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors; D013315:Stress, Psychological / Q000150:complications; D014505:Urban Population
D004041:Dietary Fats; D004043:Dietary Fiber