Melanotic neuroectodermal tumor of infancy. A case report of paratesticular primary with lymph node involvement.
A 17-month-old boy had a melanotic neuroectodermal tumor of infancy in the left paratesticular region affecting the retroperitoneal lymph nodes. Immunohistochemical and ultrastructural study showed phenotypical diversity of the proliferating cells within a spectrum of neuroectodermal differentiation. Urinary catecholamine levels were initially elevated but returned to normal values after complete eradication of the tumor. The patient received chemotherapy and is now well, without evidence of disease 28 months after surgery.
De Chiara
A
A
Department of Pathology and Laboratory Medicine, Childrens Hospital Los Angeles, California 90027.
Van Tornout
J M
JM
Hachitanda
Y
Y
Ortega
J A
JA
Shimada
H
H
D014408:Biomarkers, Tumor / Q000652:urine; D003131:Combined Modality Therapy; D006719:Homovanillic Acid / Q000652:urine; D006801:Humans; D007223:Infant; D008207:Lymphatic Metastasis; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000473:pathology* / Q000556:secondary / Q000628:therapy / Q000652:urine; D013736:Testicular Neoplasms / Q000473:pathology* / Q000628:therapy / Q000652:urine; D014642:Vanilmandelic Acid / Q000652:urine
D014408:Biomarkers, Tumor; D014642:Vanilmandelic Acid; D006719:Homovanillic Acid