[A comparative analysis of the change in the EEG spectral characteristics of rats during the activation and suppression of the catecholaminergic systems].
To find EEG-markers of catecholaminergic activation shifts EEG power spectra of white rats were computed before and after intraperitoneal injections of propranolol, metaproterenol, haloperidol, amantadine, or isotonic sodium chloride solution. Differential spectral characteristics were undergone to factor analysis and discriminant analysis. Factors with similar structure for both catecholaminergic systems were revealed in EEG-reactions to mutually antagonistic injections and relatively specific factors as well. The leading factor of adrenotropic injections described the augmentation of the spectral power in the range of 9-16 Hz induced by propranolol and its reduction by metaproternol. Similar factor was also revealed in reactions to dopaminotropic injections with the smaller value of discriminant function coefficient. One more common feature of EEG-reactions to catecholaminergic disturbances was found to consist of the reciprocal narrow-band shifts in the theta- and delta-diapasons. The leading factor for the recognition of dopaminotropic disturbances described the increase of EEG power in the band of 19-30 Hz at activation and its reduction at suppression of the transmitter system.
Kurova
N S
NS
Paniushkina
S V
SV
D000818:Animals; D003700:Delta Rhythm / Q000187:drug effects / Q000706:statistics & numerical data; D016002:Discriminant Analysis; D004569:Electroencephalography / Q000187:drug effects* / Q000706:statistics & numerical data; D005163:Factor Analysis, Statistical; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects* / Q000502:physiology; D017983:Receptors, Catecholamine; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology; D013826:Theta Rhythm / Q000187:drug effects / Q000706:statistics & numerical data; D013997:Time Factors
D011941:Receptors, Adrenergic; D017983:Receptors, Catecholamine; D011954:Receptors, Dopamine
Sravnitel'nyĭ analiz izmeneniia spektral'nykh kharakteristik EEG krys pri aktivatsii i ugnetenii katekholaminergicheskikh sistem.