title: [Review of North American studies on nedocromil sodium].
abstract: Nedocromil sodium is a new prophylactic antiasthmatic medication. Its therapeutic profile is close to sodium cromoglycate but its antiinflammatory properties seem to be superior. North-American studies on this medication have shown that this preparation can inhibit the bronchial response to exercise, inhalation of cold air and to antigens. It can replace theophyllines and is a useful preparation in asthmatic subjects requiring several medications to control asthma in improving the control of asthma and reducing the need for bronchodilators. Nedocromil sodium allows for a reduction in the doses of oral steroids in some severe asthmatic subjects. Side effects are infrequent, minor and mainly consist in a feeling of bad taste.
authors.affiliation: Centre de Pneumologie, Hôpital Laval, Québec, Canada.
authors.forename: L P
authors.initials: LP
authors.lastname: Boulet
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004205:Cromolyn Sodium / Q000627:therapeutic use; D006801:Humans; D015337:Multicenter Studies as Topic; D017835:Nedocromil; D011241:Prednisone / Q000627:therapeutic use; D015363:Quinolones / Q000009:adverse effects / Q000627:therapeutic use*; D013806:Theophylline / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000894:Anti-Inflammatory Agents, Non-Steroidal; D015363:Quinolones; D017835:Nedocromil; D013806:Theophylline; D004205:Cromolyn Sodium; D011241:Prednisone
vernacular_title: Revue des études nord-américaines sur le nédocromil sodique.