title: Spinal and cortical potentials evoked by tibial nerve stimulation in humans: effects of sex, age and height.
abstract: Somatosensory evoked potentials by posterior tibial nerve stimulation at the ankle were performed in 74 healthy volunteers (36 females and 38 males) aged 14-76 years. Cortical potentials were obtained in all subjects and spinal potentials (N22) in 71 subjects. All parameters were related to subject's age, height and sex. Sex influenced only P40-N50 amplitude, which was greater in females. All latencies of spinal and cortical components increased in a similar manner with subject's height (about 0.16-0.18 ms per cm), whereas the N22-P40 interpeak latency was independent from height, but related to T12-Cz distance. Absolute latencies of the spinal and of most cortical components, but not interpeak latencies, increased with subject's age (about 0.06-0.09 ms per year). The parameters to compute normative data (according to univariate or bivariate regression models) are furnished. Limits of right-left differences are reported.
authors.affiliation: Istituto Neurologico C Mondino, Università di Pavia.
authors.forename: A
authors.initials: A
authors.lastname: Romani
authors.forename: R
authors.initials: R
authors.lastname: Bergamaschi
authors.forename: M
authors.initials: M
authors.lastname: Versino
authors.forename: L
authors.initials: L
authors.lastname: Delnevo
authors.forename: R
authors.initials: R
authors.lastname: Callieco
authors.forename: V
authors.initials: V
authors.lastname: Cosi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology; D001827:Body Height / Q000502:physiology; D005073:Evoked Potentials, Somatosensory; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time; D012727:Sex Characteristics; D013116:Spinal Cord / Q000502:physiology*; D009435:Synaptic Transmission; D013979:Tibial Nerve / Q000502:physiology*