Small cell (neuroendocrine) carcinoma of the vagina.
We report a case of vaginal small cell (neuroendocrine) carcinoma. Immunostaining for neuron-specific enolase, PGP 9.5, chromogranin, synaptophysin, Leu 7 and cytokeratin was positive. Neurosecretory granules were found by electronmicroscopy. There was local recurrence and regional lymph node metastases. The patient survived for 10 months following local surgical therapy only.
Miliauskas
J R
JR
Division of Tissue Pathology, Gribbles Pathology, Institute of Medical & Veterinary Science, Adelaide, Australia.
Leong
A S
AS
D000368:Aged; D018288:Carcinoma, Small Cell / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D009490:Neurosecretory Systems / Q000166:cytology; D014625:Vaginal Neoplasms / Q000473:pathology* / Q000648:ultrastructure