Scaffold-associated regions: cis-acting determinants of chromatin structural loops and functional domains.
It has been proposed that scaffold-associated regions are DNA elements that form the bases of chromatin loops in eukaryotic cells. Recent evidence supports a role for these elements as cis-acting 'handlers' of both structural and functional chromatin domains.
Laemmli
U K
UK
Department of Biochemistry and Molecular Biology, University of Geneva, Switzerland.
Käs
E
E
Poljak
L
L
Adachi
Y
Y
D000818:Animals; D001483:Base Sequence; D002843:Chromatin / Q000737:chemistry* / Q000502:physiology*; D004250:DNA Topoisomerases, Type II / Q000502:physiology; D004268:DNA-Binding Proteins / Q000502:physiology; D008938:Mitosis / Q000502:physiology; D008969:Molecular Sequence Data
D002843:Chromatin; D004268:DNA-Binding Proteins; D004250:DNA Topoisomerases, Type II