[The effect of peripheral cholinergic blockers on the cocarcinogenic action of an experimental influenza infection].
The cocarcinogenic effect of chronic influenza infection was shown to be mediated by M-cholinergic structures. Administration of a M-anticholinergic agent in low dose at the key stages of chronic influenza infection development was followed by a nearly complete suppression of its cocarcinogenic action. N-anticholinergic agents failed to exert such effect.
Orlovskiĭ
A A
AA
Zalesskiĭ
V N
VN
Smelkova
M I
MI
D000818:Animals; D002908:Chronic Disease; D003043:Cocarcinogenesis; D004305:Dose-Response Relationship, Drug; D005260:Female; D009980:Influenza A virus; D008168:Lung / Q000187:drug effects / Q000473:pathology; D008175:Lung Neoplasms / Q000209:etiology* / Q000473:pathology; D008321:Mammary Glands, Animal / Q000187:drug effects / Q000473:pathology; D008325:Mammary Neoplasms, Experimental / Q000209:etiology* / Q000473:pathology; D051379:Mice; D008809:Mice, Inbred C3H; D009976:Orthomyxoviridae Infections / Q000150:complications* / Q000473:pathology; D010276:Parasympatholytics / Q000494:pharmacology*; D011976:Receptors, Muscarinic / Q000187:drug effects; D013997:Time Factors
D010276:Parasympatholytics; D011976:Receptors, Muscarinic
Vliianie perifericheskikh kholinoblokatorov na kokantserogennoe deĭstvie éksperimental'noĭ grippoznoĭ infektsii.