Identification of a protein encoded in the EB-viral open reading frame BMRF2.
Using monospecific rabbit sera against a peptide derived from a potential antigenic region of the Epstein-Barr viral amino acid sequence encoded in the open reading frame BMRF2 we could identify a protein-complex of 53/55 kDa in chemically induced B95-8, P3HR1 and Raji cell lines. This protein could be shown to be membrane-associated, as predicted by previous computer analysis of the secondary structure and hydrophilicity pattern, and may be a member of EBV-induced membrane proteins in lytically infected cells.
Modrow
S
S
Max von Pettenkofer-Institut, Munich, Federal Republic of Germany.
Höflacher
B
B
Wolf
H
H
D000595:Amino Acid Sequence; D000956:Antigens, Viral / Q000235:genetics*; D005814:Genes, Viral; D004854:Herpesvirus 4, Human / Q000235:genetics* / Q000276:immunology; D008562:Membrane Glycoproteins / Q000235:genetics / Q000276:immunology; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000737:chemistry / Q000276:immunology; D016366:Open Reading Frames; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics / Q000276:immunology*; D015678:Viral Structural Proteins / Q000235:genetics*
D000956:Antigens, Viral; D008562:Membrane Glycoproteins; D009842:Oligopeptides; D014764:Viral Proteins; D015678:Viral Structural Proteins