[Immunologic study of lymphoproliferative diseases].
Thirty six patients with stage IV lymphoproliferative diseases, were studied with a panel of monoclonal antibodies. There were 26 B-Lymphoproliferative Diseases (BLD): 11 B-chronic lymphocytic leukemia, 15 B-cell non Hodgkin lymphoma and 10 T-Lymphoproliferative Diseases (TLD): 4 T-cell non Hodgkin lymphoma, 4 adult T-cell leukemia/lymphoma, 1 T-chronic lymphocytic leukemia and 1 Sezary Syndrome. HLA-DR and CD 19 (B4) were the most common antigens found in BLD. CD4 + CD8 was the most common phenotype in TLD. 13 out of 26 BLD and 1 out of 10 TLD, patient were alive at the end of a 4 year observation period. Our study shows that immunophenotyping is a very useful diagnostic test in lymphoproliferative diseases. Along with cytology and histopathology, it can better define different pathologic groups and lead more specific treatments.
Cabrera
M E
ME
Departamento de Medicina (División Cs M Oriente) Universidad de Chile, Santiago.
Majlis
A
A
Labra
S
S
Carrasco
A M
AM
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D008232:Lymphoproliferative Disorders / Q000276:immunology* / Q000473:pathology; D008297:Male; D008875:Middle Aged
Estudio inmunológico de enfermedades linfoproliferativas.