title: Thyroid storm associated with probable subclinical hypoadrenocorticism in an elderly woman.
abstract: A 73-year-old woman was admitted to the hospital for severe persistent vomiting with fever, drowsiness, and weight loss. Elevated serum levels of thyroid hormones and the presence of a consciousness disorder with fever and vomiting led to the diagnosis of thyroid storm. A low normal concentration of serum cortisol, urinary 17-hydroxycorticosteroids and an elevated plasma level of corticotropin suggest that an inadequate adrenal reserve have been involved in the pathogenesis of the thyroid storm in this patient. She responded to the administration of intravenous methimazole and oral supersaturated potassium iodide solution.
authors.affiliation: Third Department of Internal Medicine, Nagoya City University Medical School, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kawaguchi
authors.forename: S
authors.initials: S
authors.lastname: Iwata
authors.forename: Y
authors.initials: Y
authors.lastname: Kamiya
authors.forename: F
authors.initials: F
authors.lastname: Hayakawa
authors.forename: T
authors.initials: T
authors.lastname: Fujii
authors.forename: J
authors.initials: J
authors.lastname: Ito
authors.forename: N
authors.initials: N
authors.lastname: Sakuma
authors.forename: T
authors.initials: T
authors.lastname: Fujinami
mesh_terms: D015065:17-Hydroxycorticosteroids / Q000652:urine; D015068:17-Ketosteroids / Q000652:urine; D000305:Adrenal Cortex Hormones / Q000097:blood*; D000311:Adrenal Glands / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000368:Aged; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008713:Methimazole / Q000627:therapeutic use; D011193:Potassium Iodide / Q000627:therapeutic use; D013958:Thyroid Crisis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013963:Thyroid Hormones / Q000097:blood
chemical_list: D015065:17-Hydroxycorticosteroids; D015068:17-Ketosteroids; D000305:Adrenal Cortex Hormones; D013963:Thyroid Hormones; D011193:Potassium Iodide; D008713:Methimazole; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone