title: Cholecystokinin, gastrin and stress hormone responses in marathon runners.
abstract: The purpose of this investigation was to determine the influence of long-distance running on the secretion of the gastrointestinal peptide hormones cholecystokinin (CCK) and gastrin. Several known stress hormones, ACTH, cortisol and norepinephrine, were also measured. The hormones were estimated before and after a competitive marathon run of 46.5 km and under control conditions a few weeks later. Except gastrin, all hormones were significantly higher under prerun conditions than under control conditions and were highest after the run. The most marked prerun elevation was in CCK. Therefore, CCK seems to be an important regulation factor in response to anticipatory stress.
authors.affiliation: Klinikum rechts der Isar, Institute of Clinical Chemistry, Munich, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Philipp
authors.forename: T
authors.initials: T
authors.lastname: Wilckens
authors.forename: E
authors.initials: E
authors.lastname: Friess
authors.forename: P
authors.initials: P
authors.lastname: Platte
authors.forename: K M
authors.initials: KM
authors.lastname: Pirke
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D002766:Cholecystokinin / Q000097:blood*; D005260:Female; D005755:Gastrins / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood; D012420:Running; D013312:Stress, Physiological / Q000378:metabolism*
chemical_list: D005755:Gastrins; D000324:Adrenocorticotropic Hormone; D002766:Cholecystokinin; D006854:Hydrocortisone; D009638:Norepinephrine