Hepaticopancreaticogastroduodenectomy with transplantation for metastatic islet cell carcinoma in childhood.
Symptomatic islet cell carcinoma of the pancreas with liver metastasis, a rare tumor cured only by complete resection, was unresponsive to chemotherapy and was treated with hepaticopancreaticogastroduodenectomy en bloc resection with transplantation in an 11-year-old girl. This radical surgery in conjunction with adjuvant chemotherapy and interstitial and external beam irradiation has resulted in symptomatic relief and no evidence of disease at 15 months posttransplant.
Lobe
T E
TE
Department of Surgery, University of Tennessee, Memphis.
Vera
S R
SR
Bowman
L C
LC
Fontanesi
J
J
Britt
L G
LG
Gaber
A O
AO
D007516:Adenoma, Islet Cell / Q000556:secondary* / Q000601:surgery*; D000714:Anastomosis, Surgical; D002648:Child; D003131:Combined Modality Therapy; D004386:Duodenum / Q000637:transplantation*; D005260:Female; D006801:Humans; D007583:Jejunum / Q000601:surgery; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods; D016035:Pancreas Transplantation / Q000379:methods; D010190:Pancreatic Neoplasms / Q000601:surgery*; D013154:Spleen / Q000637:transplantation; D013270:Stomach / Q000637:transplantation*