Recessively determined chylous ascites--a case report and possible mouse model.
A male infant, whose parents were first cousins, was born with tense chylous ascites, mild generalized oedema and facial dysmorphism. The baby initially seemed well but subsequently probably aspirated, developed septicaemia and finally died at 26 days from a bleeding diathesis, possibly secondary to liver dysfunction. No cause for the chylous ascites was found at post mortem. This case is presumed to represent an example of recessively determined chylous ascites. The mouse mutant Chy may be an homologous condition.
Woods
C G
CG
Department of Medical Genetics, Churchill Hospital, Oxford, UK.
Pearce
J L
JL
Huson
S M
SM
D000818:Animals; D002915:Chylous Ascites / Q000235:genetics*; D004195:Disease Models, Animal; D005808:Genes, Recessive; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D051379:Mice