title: Subgroup I serotype 3 human rotavirus strains with long RNA pattern as a result of naturally occurring reassortment between members of the bovine and AU-1 genogroups.
abstract: Two human rotavirus strains, PCP 5 and MZ 58, which possessed an unusual combination of subgroup (I), serotype (3) and RNA pattern (long) were examined by RNA-RNA hybridization to determine their genogroup. While these two strains did not belong to either the Wa or the DS-1 genogroup, PCP 5 and MZ 58 possessed seven gene segments that formed hybrids with bovine rotavirus strain NCDV and four gene segments that formed hybrids with human rotavirus strain AU-1. These results suggest that PCP 5 and MZ 58 were intergenogroup reassortants formed in nature between a member of the bovine rotavirus genogroup and a member of the AU-1 genogroup.
authors.affiliation: Department of Laboratory Medicine, Akita University School of Medicine, Japan.
authors.forename: O
authors.initials: O
authors.lastname: Nakagomi
authors.forename: E
authors.initials: E
authors.lastname: Kaga
authors.forename: G
authors.initials: G
authors.lastname: Gerna
authors.forename: A
authors.initials: A
authors.lastname: Sarasini
authors.forename: T
authors.initials: T
authors.lastname: Nakagomi
mesh_terms: D000818:Animals; D002417:Cattle; D005814:Genes, Viral / Q000235:genetics; D009693:Nucleic Acid Hybridization; D015347:RNA Probes / Q000235:genetics; D012367:RNA, Viral / Q000235:genetics*; D011995:Recombination, Genetic / Q000235:genetics*; D012401:Rotavirus / Q000235:genetics*
chemical_list: D015347:RNA Probes; D012367:RNA, Viral