[Serological verification of the role of enteroviruses in the etiology of polyradiculoneuritis and aseptic meningoencephalitis].
In a group of 38 patients with the Guillain-Barré syndrome (SGB) and a group of 38 patients selected at random who suffered from meningoencephalitis the authors compared the characteristics by age, sex, onset of the disease (month of the year) and intervals between the onset of the disease and collection of serum samples. Using the neutralization microtest, the sera were examined for antibodies against 23 serotypes of enteroviruses incl. polioviruses. The groups differed significantly in the following indicators: the SGP group had a non-seasonal annual distribution, it included different age groups, there were longer intervals of sample collection. There were fewer cases with an assessed enteroviral aetiology, no case with a polioviral aetiology. More detailed analysis of serological results revealed, that the group does not differ fundamentally as regards the immunological experience of individuals with enteroviruses before the disease. The authors discuss the need of more detailed examinations of the enteroviral aetiology in all cases of SGB.
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Státní zdravotní ústav, Praha.
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D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004770:Enterovirus / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000382:microbiology*; D008875:Middle Aged; D011129:Polyradiculoneuropathy / Q000382:microbiology*
Sérologický průkaz podílu enterovirů na etiologii polyradikuloneuritidy a aseptické meningoencefalitidy.