title: [Autologous bone marrow graft in solid tumors in childhood].
abstract: Curability in children suffering from malignant solid tumor is 50%. Thus, high dose chemotherapy with or without total body irradiation followed by autologous bone marrow transplantation (ABMT) has been proposed to patients suffering from cancer either at initial diagnosis (poor prognosis tumor) or at relapse. Thanks to these studies, drugs having dose effects properties have been selected. In some tumors, ABMT has significantly improved patients median survival. It remains to be determined if: 1. high dose chemotherapy protocols with ABMT are superior to new aggressive chemotherapeutic protocol without ABMT. 2. ABMT increases the curability of high risk patients.
authors.affiliation: Unité d'Hémato-Oncologie, Hôpital Universitaire des Enfants, Bruxelles.
authors.forename: C
authors.initials: C
authors.lastname: Devalck
authors.forename: A
authors.initials: A
authors.lastname: Ferster
authors.forename: M H
authors.initials: MH
authors.lastname: De Laet
authors.forename: S
authors.initials: S
authors.lastname: Nafa
authors.forename: W
authors.initials: W
authors.lastname: Bujan
authors.forename: N
authors.initials: N
authors.lastname: Azzi
authors.forename: H
authors.initials: H
authors.lastname: Ben Salah
authors.forename: F
authors.initials: F
authors.lastname: Corrazza
authors.forename: P
authors.initials: P
authors.lastname: Vergauwen
authors.forename: E
authors.initials: E
authors.lastname: Sariban
mesh_terms: D016026:Bone Marrow Transplantation; D001932:Brain Neoplasms / Q000628:therapy; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D007680:Kidney Neoplasms / Q000628:therapy; D009369:Neoplasms / Q000628:therapy*; D009373:Neoplasms, Germ Cell and Embryonal / Q000628:therapy; D009447:Neuroblastoma / Q000628:therapy; D012512:Sarcoma, Ewing / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000628:therapy; D014182:Transplantation, Autologous; D009396:Wilms Tumor / Q000628:therapy
vernacular_title: Greffe de moelle autologue dans les tumeurs solides des enfants.