title: Expression pattern of the activin receptor type IIA gene during differentiation of chick neural tissues, muscle and skin.
abstract: To elucidate target cells of activins during embryogenesis we isolated cDNAs of chick activin receptor type II (cActR-II) and studied expression patterns of the cActR-II gene by in situ hybridization. Transcripts of cActR-II were observed in neuroectoderm developing to spinal cord, brain and eyes, in surface ectoderm differentiating to epidermis, and in myotomes differentiating to muscles. The expression patterns of cActR-II suggest that activin and its receptor are involved in differentiation of chick neural tissues, muscle and skin after inducing the dorsal mesoderm.
authors.affiliation: Department of Ophthalmology, Okayama University Medical School, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ohuchi
authors.forename: S
authors.initials: S
authors.lastname: Noji
authors.forename: E
authors.initials: E
authors.lastname: Koyama
authors.forename: F
authors.initials: F
authors.lastname: Myokai
authors.forename: K
authors.initials: K
authors.lastname: Nishikawa
authors.forename: T
authors.initials: T
authors.lastname: Nohno
authors.forename: K
authors.initials: K
authors.lastname: Tashiro
authors.forename: K
authors.initials: K
authors.lastname: Shiokawa
authors.forename: N
authors.initials: N
authors.lastname: Matsuo
authors.forename: S
authors.initials: S
authors.lastname: Taniguchi
mesh_terms: D029404:Activin Receptors; D028341:Activins; D000595:Amino Acid Sequence; D000818:Animals; D002454:Cell Differentiation / Q000235:genetics; D002642:Chick Embryo; D004475:Ectoderm / Q000378:metabolism; D007265:Inhibins / Q000378:metabolism*; D008969:Molecular Sequence Data; D009132:Muscles / Q000196:embryology / Q000378:metabolism*; D009420:Nervous System / Q000196:embryology / Q000378:metabolism*; D011956:Receptors, Cell Surface / Q000235:genetics*; D015183:Restriction Mapping; D016415:Sequence Alignment; D012867:Skin / Q000196:embryology / Q000378:metabolism*
chemical_list: D011956:Receptors, Cell Surface; D028341:Activins; D007265:Inhibins; D029404:Activin Receptors