title: Hepatitis C virus antibodies in dialysis pediatric patients.
abstract: A new 4-antigen recombinant immunoblot assay (4-RIBA) for confirmation of hepatitis C virus (HCV) C-100 enzyme-linked immunosorbent assay (ELISA) reactivity was tested in serum samples of 11 pediatric patients on dialysis. Of 6 HCV C-100 ELISA-positive samples, all were 4-RIBA positive. The 2nd generation ELISA picked up 1 additional case confirmed by 4-RIBA. The 2nd generation tests increased the prevalence of HCV-positive cases.
authors.affiliation: Servizio di Immunoematologia e Trasfusione, Ospedale Pediatrico Giovanni XXIII, Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Di Loreto
authors.forename: M
authors.initials: M
authors.lastname: Ferrante
authors.forename: A
authors.initials: A
authors.lastname: Panaro
authors.forename: P
authors.initials: P
authors.lastname: Sorino
authors.forename: V
authors.initials: V
authors.lastname: Collela
authors.forename: D A
authors.initials: DA
authors.lastname: Caringella
mesh_terms: D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods / Q000706:statistics & numerical data; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D015151:Immunoblotting / Q000379:methods / Q000706:statistics & numerical data; D006435:Renal Dialysis / Q000009:adverse effects*; D012680:Sensitivity and Specificity
chemical_list: D006508:Hepatitis Antibodies