title: Why is the genome variable? Insights from Drosophila.
abstract: The analysis of variation in DNA restriction maps and DNA sequence in natural populations of Drosophila melanogaster and related species has revealed a remarkable richness of diversity. This review describes some of the results of population genetic studies of this variation that are beginning to reveal how interactions between natural selection, genetic drift, mutation rate, recombination rate and population size have contributed to the observed patterns.
authors.affiliation: Section of Genetics and Development, Cornell University, Ithaca, NY 14853.
authors.forename: C F
authors.initials: CF
authors.lastname: Aquadro
mesh_terms: D000818:Animals; D005075:Biological Evolution; D004251:DNA Transposable Elements; D004330:Drosophila / Q000235:genetics*; D014644:Genetic Variation; D005828:Genetics, Population; D011110:Polymorphism, Genetic
chemical_list: D004251:DNA Transposable Elements