Argyrophilic nucleolar organizer regions in breast cancer: prognostic significance.
109 cases of breast cancer were examined in order to assess correlation between the number and size of argyrophilic nucleolar organizer regions (AgNORs) on one hand and prognosis of the disease on the other hand. Results indicate that an indirect correlation exists between AgNOR counts and survival rate of patients. Cases with short survival were observed having significantly frequent AgNORs larger than 5 microns.
Kolár
Z
Z
Institute of Pathology, Faculty of Medicine, Palacký University, Olomouc, Czechoslovakia.
Zábranský
T
T
Mattler
K
K
Zábranský
E
E
D001943:Breast Neoplasms / Q000401:mortality / Q000648:ultrastructure*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000401:mortality / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D011379:Prognosis; D012189:Retrospective Studies; D016622:Silver Staining; D015996:Survival Rate