Tetrodotoxin and its analogues in extracts from the toad Atelopus oxyrhynchus (family: Bufonidae).
Tetrodotoxin and its analogues, 4-epitetrodotoxin and 4,9-anhydrotetrodotoxin, were detected in the toad Atelopus oxyrhynchus by HPLC analysis. The toxin and its analogues were still present in a specimen which lived 3.5 years in captivity.
Yotsu-Yamashita
M
M
Faculty of Agriculture, Tohoku University, Sendai, Japan.
Mebs
D
D
Yasumoto
T
T
D000818:Animals; D002025:Bufonidae; D002851:Chromatography, High Pressure Liquid; D051379:Mice; D015222:Sodium Channels / Q000187:drug effects; D013050:Spectrometry, Fluorescence; D013779:Tetrodotoxin / Q000032:analysis* / Q000633:toxicity / Q000031:analogs & derivatives; D014020:Tissue Extracts / Q000032:analysis*
D015222:Sodium Channels; D014020:Tissue Extracts; C047739:anhydrotetrodotoxin; D013779:Tetrodotoxin; C047738:4-epitetrodotoxin