title: Differential splicing of Epstein-Barr virus immediate-early RNA.
abstract: A variant form of splicing of RNA crossing the Epstein-Barr virus (EBV) BZLF1 gene was observed in the late productive cycle of EBV. This splice omits the middle exon of BZLF1 and joins the outer two exons of BZLF1 in frame, but the shortened form of BZLF1 protein (Z delta) could not be detected in natural EBV infections.
authors.affiliation: Ludwig Institute for Cancer Research, St. Mary's Hospital Medical School, London, United Kingdom.
authors.forename: R
authors.initials: R
authors.lastname: Lau
authors.forename: G
authors.initials: G
authors.lastname: Packham
authors.forename: P J
authors.initials: PJ
authors.lastname: Farrell
mesh_terms: D015153:Blotting, Western; D002460:Cell Line; D004247:DNA; D004268:DNA-Binding Proteins / Q000235:genetics; D005091:Exons; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D016133:Polymerase Chain Reaction; D012326:RNA Splicing; D012367:RNA, Viral / Q000235:genetics / Q000378:metabolism*; D015534:Trans-Activators; D014764:Viral Proteins / Q000235:genetics; D014779:Virus Replication
chemical_list: C063676:BZLF1 protein, Herpesvirus 4, Human; D004268:DNA-Binding Proteins; D012367:RNA, Viral; D015534:Trans-Activators; D014764:Viral Proteins; D004247:DNA