title: The brain in cerebral malaria: a pathological study of 24 fatal cases in Papua New Guinea.
abstract: The pathological features of cerebral malaria in 24 fatal cases are described. The cases included 18 adults aged from 16 to 45 years and 6 children aged from 1 to 15 years. All were unconscious before death. Gross pathological findings in the brain included cerebral oedema, vascular congestion and petechial haemorrhages. Little clinical and laboratory information was available on these patients. Histological examination revealed parasitized red blood cells in all, ring haemorrhages in 6, hyaline material in the wall of medium-sized blood vessels in 4, and vascular thrombosis in 4.
authors.affiliation: Department of Pathology and Clinical Sciences, University of Papua New Guinea, Port Moresby.
authors.forename: S K
authors.initials: SK
authors.lastname: SenGupta
authors.forename: S
authors.initials: S
authors.lastname: Naraqi
mesh_terms: D000293:Adolescent; D000328:Adult; D001929:Brain Edema / Q000469:parasitology / Q000473:pathology*; D002423:Cause of Death; D002543:Cerebral Hemorrhage / Q000469:parasitology / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D016779:Malaria, Cerebral / Q000150:complications / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology; D008875:Middle Aged; D010219:Papua New Guinea / Q000453:epidemiology