[Treponemal pallidum specific 19S-IgM haemagglutination test and its clinical significance].
74 samples of 53 cases were detected with 19 S-IgM-TPHA. The sensitivity was 97.37% and the specificity was more than 99%. 19S-IgM-TPHA was not interfered by rheumatoid factor. It was used to define congenital syphilis, to determine the necessity of treatment and reinfection, to diagnose syphilis without lesion and detailed case history as well as neurosyphilis. The results of 19S-IgM-TPHA were not consistent with those of routine screen and definite tests (Kappa < 0.4), so it can not be replaced by other methods.
Dai
Y L
YL
Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing.
D000907:Antibodies, Bacterial / Q000032:analysis*; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis*; D007231:Infant, Newborn; D009494:Neurosyphilis / Q000175:diagnosis; D013587:Syphilis / Q000175:diagnosis*; D013588:Syphilis Serodiagnosis / Q000379:methods*; D013590:Syphilis, Congenital / Q000175:diagnosis; D014210:Treponema pallidum / Q000276:immunology*
D000907:Antibodies, Bacterial; D007075:Immunoglobulin M