title: Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis.
authors.affiliation: Department of Microbiology, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4799.
authors.forename: A D
authors.initials: AD
authors.lastname: O'Brien
authors.forename: V L
authors.initials: VL
authors.lastname: Tesh
authors.forename: A
authors.initials: A
authors.lastname: Donohue-Rolfe
authors.forename: M P
authors.initials: MP
authors.lastname: Jackson
authors.forename: S
authors.initials: S
authors.lastname: Olsnes
authors.forename: K
authors.initials: K
authors.lastname: Sandvig
authors.forename: A A
authors.initials: AA
authors.lastname: Lindberg
authors.forename: G T
authors.initials: GT
authors.lastname: Keusch
mesh_terms: D001427:Bacterial Toxins / Q000235:genetics / Q000378:metabolism* / Q000494:pharmacology; D001483:Base Sequence; D002240:Carbohydrate Sequence; D004195:Disease Models, Animal; D004405:Dysentery, Bacillary / Q000150:complications / Q000382:microbiology*; D004705:Endocytosis; D004768:Enterotoxins / Q000235:genetics / Q000378:metabolism* / Q000494:pharmacology; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D006463:Hemolytic-Uremic Syndrome / Q000209:etiology; D006801:Humans; D008969:Molecular Sequence Data; D014176:Protein Biosynthesis / Q000187:drug effects; D011956:Receptors, Cell Surface / Q000378:metabolism; D022622:Shiga Toxin 1; D022641:Shiga Toxin 2; D022603:Shiga Toxins; D012760:Shigella / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity; D013329:Structure-Activity Relationship; D014281:Trihexosylceramides / Q000378:metabolism; D014774:Virulence
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D011956:Receptors, Cell Surface; D022622:Shiga Toxin 1; D022641:Shiga Toxin 2; D022603:Shiga Toxins; D014281:Trihexosylceramides; C018549:globotriaosylceramide