[Cells inhibiting the formation of stromal CFU-F colonies in bone marrow cultures].
The presence of embryonal calf serum (ECS) in the cultural medium in necessary for the inhibition of CFUf colony growth in rabbit bone marrow cultures by hemopoietic and lymphoid cells. The inhibitory effect is sharply decreased when, besides ECS, the cultural medium contains sera autologous for the reacting cells (rabbit serum), and sera of mature animals of some other species (mouse, rat). The inhibitory activity depends on soluble factors penetrating millipore filters. It has been revealed that the cells inhibiting CFUf growth have the marker F480. T-cells, probably, are not involved in the effect studied.
Gorskaia
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Shuklina
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D000818:Animals; D001854:Bone Marrow Cells; D002448:Cell Adhesion; D002450:Cell Communication; D002478:Cells, Cultured / Q000166:cytology; D003114:Colony-Forming Units Assay; D017077:Culture Media, Conditioned; D005347:Fibroblasts / Q000166:cytology; D008198:Lymph Nodes / Q000166:cytology*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000166:cytology*; D013997:Time Factors
D017077:Culture Media, Conditioned
O kletkakh, ingibiruiushchikh obrazovanie stromal'nykh KOK-F koloniĭ, v kostnomozgovykh kul'turakh.