title: Detection of human papillomavirus DNA without amplification: prospects for clinical utility.
abstract: Certain HPV types are major risk factors for the development of cervical and other human cancers. This chapter describes some of the problems which have precluded accurate diagnosis of HPV-related conditions in many studies. Despite the confusion, a multitude of reports demonstrate that HPV DNA testing has clinical utility, and future investigations should be directed at more accurately delineating its role in human health care.
authors.affiliation: Digene Diagnostics, Inc., Silver Spring, MD 20901.
authors.forename: A
authors.initials: A
authors.lastname: Lörincz
mesh_terms: D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D005784:Gene Amplification; D006801:Humans; D027383:Papillomaviridae / Q000235:genetics*; D014412:Tumor Virus Infections / Q000175:diagnosis*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis
chemical_list: D004279:DNA, Viral