[Kidney failure as a complication of the treatment of pulmonary paracoccidioidomycosis].
Sulfadiazine is one of the drugs of choice in the treatment of paracoccidioidomycosis. Side effects are uncommon. Cutaneous and gastrointestinal reactions and rarely leucopenia and jaundice may occur. A patient on sulfadiazine 6 g daily exhibiting a good response is reported. On the 12th day, he presented an intense abdominal pain and reduced urinary output. An ultrasonography revealed diffuse calculosis in urinary tract. Peritoneal dialysis, urinary alkalinization and rehydration were instituted with complete restoration of renal function. This case illustrates the importance of an adequate hydratation of patients receiving sulfadiazine, a simple measure in the prevention of this uncommon complication which carries a high morbidity.
Fiks
I N
IN
Disciplina de Pneumologia, Faculdade de Medicina, Universidade de São Paulo.
Follador
C R
CR
Barbas Filho
J V
JV
Kairalla
R A
RA
Oliveira-Vianna
E dos S
Edos S
Stávale
M L
ML
de Carvalho
C R
CR
D058186:Acute Kidney Injury / Q000139:chemically induced*; D006801:Humans; D008172:Lung Diseases, Fungal / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010229:Paracoccidioidomycosis / Q000188:drug therapy*; D013411:Sulfadiazine / Q000009:adverse effects* / Q000627:therapeutic use
D013411:Sulfadiazine
Insuficiência renal como complicação do tratamento da paracoccidioidomicose pulmonar.