title: [Conditioning and sensitization in the edible snail: the neurophysiological and metabolic characteristics].
abstract: Electrophysiological parameters and bound calcium (Ca(b)) level dynamics during sensitization development or conditioning of food aversion were studied in the command neurons of defense behaviour in the snail Helix lucorum. Responses evoked by a testing sensory stimulus were facilitated 50-60 min after the first sensitizing stimulation, while conditioned responses appeared 80-90 min after the first conditioning. It was the most essential electrophysiological difference between the long-term sensitization and conditioning. Analysis of the Ca(b)) dynamics in the neurons showed significant differences in calcium-dependent metabolism during the sensitization and conditioning, likely underlying the electrophysiological differences.
authors.forename: V P
authors.initials: VP
authors.lastname: Nikitin
authors.forename: S A
authors.initials: SA
authors.lastname: Kozyrev
authors.forename: M O
authors.initials: MO
authors.lastname: Samoĭlov
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology*; D004594:Electrophysiology; D004924:Escape Reaction / Q000187:drug effects / Q000502:physiology; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology; D006372:Helix, Snails / Q000187:drug effects / Q000502:physiology*; D008839:Microelectrodes; D009474:Neurons / Q000187:drug effects / Q000502:physiology; D010936:Plant Extracts / Q000494:pharmacology; D011803:Quinine / Q000494:pharmacology; D012054:Reinforcement, Psychology; D014110:Touch / Q000502:physiology
chemical_list: D010936:Plant Extracts; D011803:Quinine; D002118:Calcium
vernacular_title: Obuslovlivanie i sensitizatsiia u vinogradnoĭ ulitki: neĭrofiziologicheskie i metabolicheskie osobennosti.