Polymerase chain reaction and other gene techniques in pharmacogenetics: an introduction and review.
The author gives a short description of the polymerase chain reaction technique and restriction fragment length polymorphism which revolutionized molecular biology and have entered pharmacogenetics, too. Examples of the use of these techniques are given in the polymorphism of oxidative (phase I) and conjugative (phase II) reactions.
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Postgraduate Medical University, I. Department of Medicine, Budapest, Hungary.
D000818:Animals; D004587:Electrophoresis, Agar Gel; D005821:Genetic Techniques; D005838:Genotype; D006801:Humans; D010597:Pharmacogenetics; D016133:Polymerase Chain Reaction / Q000379:methods*; D011110:Polymorphism, Genetic