title: Synchronization of estrus in dairy goats given norgestomet and estradiol valerate at various stages of the estrous cycle.
abstract: Dairy goats were given subcutaneous implants with 3 mg of norgestomet (NOR) and IM injections of 0.625 mg of estradiol valerate and 0.375 mg of norgestomet on day 0 of the estrous cycle (estrus; NOR 0, n = 18), on postestrus day 4 (NOR 4, n = 18), or on postestrus day 11 (NOR 11, n = 15). Ear implants were removed after 9 days. Mean (+/- SE) hours from removal of ear implants to onset of estrus and proportion of goats responding were 36 +/- 3.8 and 83%, 33 +/- 4.0 and 61%, and 36 +/- 2.7 and 93% for groups NOR 0, NOR 4, and NOR 11, respectively. There were no significant differences between treatment groups in time to onset of estrus. The percentage of goats in group NOR 11 that had signs of estrus was significantly greater than the percentage of goats in group NOR 4. Of the goats in groups NOR 0, NOR 4, and NOR 11 that had signs of estrus, 53, 55, and 86%, respectively, had onset of behavioral estrus between 24 and 48 hours after implant removal. All goats that had signs of estrus had onset of behavioral estrus between 12 and 72 hours after implant removal. Mean (+/- SE) hours from removal of ear implants to time of peak concentrations of luteinizing hormone (LH) were 49 +/- 4.1, 49 +/- 3.8, and 49 +/- 4.0 for groups NOR 0, NOR 4, NOR 11, respectively (not different). The percentage of goats in group NOR 11 that had LH peaks was significantly greater than the percentage of goats in group NOR 4.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Large Animal Medicine and Surgery, Texas A&M University, College Station 77843.
authors.forename: K N
authors.initials: KN
authors.lastname: Bretzlaff
authors.forename: L C
authors.initials: LC
authors.lastname: Nuti
authors.forename: R G
authors.initials: RG
authors.lastname: Elmore
authors.forename: S A
authors.initials: SA
authors.lastname: Meyers
authors.forename: J N
authors.initials: JN
authors.lastname: Rugila
authors.forename: S P
authors.initials: SP
authors.lastname: Brinsko
authors.forename: T L
authors.initials: TL
authors.lastname: Blanchard
authors.forename: P G
authors.initials: PG
authors.lastname: Weston
mesh_terms: D000818:Animals; D004343:Drug Implants; D004958:Estradiol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D004966:Estrogens, Conjugated (USP) / Q000008:administration & dosage / Q000494:pharmacology; D004973:Estrus Synchronization / Q000187:drug effects*; D005260:Female; D006041:Goats / Q000502:physiology*; D007273:Injections, Intramuscular / Q000662:veterinary; D007986:Luteinizing Hormone / Q000097:blood; D011282:Pregnenediones / Q000008:administration & dosage / Q000494:pharmacology*; D011374:Progesterone / Q000097:blood; D045167:Progesterone Congeners / Q000008:administration & dosage / Q000494:pharmacology; D012726:Sexual Behavior, Animal / Q000187:drug effects
chemical_list: D004343:Drug Implants; D004966:Estrogens, Conjugated (USP); D011282:Pregnenediones; D045167:Progesterone Congeners; C100284:norgestomet; D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone