Assignment of the rat genes coding for alpha 1-antitrypsin (PI), phosphoenolpyruvate carboxykinase (PEPCK), alcohol dehydrogenase (ADH), and fructose-1,6-bisphosphatase (FDP).
The chromosomal localization of four genes which are expressed mainly in the liver has been undertaken for the rat. Using a panel of hybrid clones segregating rat chromosomes, and Southern blot analysis, alpha 1-AT (PI), PEPCK, ADH and FDP are assigned to rat Chromosomes (Chr) 6, 3, 2 and 17, respectively. Groups of synteny among rat, mouse and human species are discussed in relationship to the new assignments.
Fulchignoni-Lataud
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MC
Génétique de la Différenciation URA 1149 CNRS, Institut Pasteur, Paris, France.
Szpirer
J
J
Levan
G
G
Weiss
M C
MC
D000426:Alcohol Dehydrogenase / Q000235:genetics*; D000818:Animals; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D006597:Fructose-Bisphosphatase / Q000235:genetics*; D006822:Hybrid Cells; D051379:Mice; D010729:Phosphoenolpyruvate Carboxykinase (GTP) / Q000235:genetics*; D051381:Rats; D000515:alpha 1-Antitrypsin / Q000235:genetics*
D000515:alpha 1-Antitrypsin; D000426:Alcohol Dehydrogenase; D006597:Fructose-Bisphosphatase; D010729:Phosphoenolpyruvate Carboxykinase (GTP)