Comparison between first and second generation tests to determine the frequency of anti-HCV antibodies in uremic patients in replacement dialytic therapy.
Research was carried out on 74 hemodialysis patients to determine the frequency of anti-HCV antibodies; this was done by means of the 1st and 2nd generation screening and control tests. The 1st generation tests showed 9 HCV-seropositive patients, while the 2nd generation tests demonstrated 15 HCV-seropositive patients. It seems evident that the 2nd generation tests are more sensitive than those of the 1st.
Mazzotta
L
L
Department of Nephrology, Hospital of Lucca, Italy.
Landucci
G
G
Pfanner
L
L
Carlini
A
A
Angelini
D
D
Giusti
R
R
Antonelli
A
A
D000328:Adult; D000368:Aged; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D007118:Immunoassay / Q000379:methods* / Q000706:statistics & numerical data; D015151:Immunoblotting / Q000379:methods / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects; D012680:Sensitivity and Specificity; D014511:Uremia / Q000628:therapy
D006508:Hepatitis Antibodies