title: Percutaneous transcatheter embolization for control of life-threatening pelvic hemorrhage from gestational trophoblastic disease.
abstract: Pelvic hemorrhage from gestational trophoblastic disease remains a common and vexing problem. Traditional surgical therapy, including hysterectomy and hypogastric artery ligation, may be technically difficult as well as hazardous to debilitated patients. In contrast, percutaneous transcatheter embolization specifically occludes the vessels that directly contribute to bleeding. Other potential advantages include avoidance of general anesthesia and major surgery, a rapid recovery period, and preservation of fertility. Various embolic materials allow one to tailor the duration of occlusion to the underlying disorder. Reported complications are rare and generally involve aberrant emboli or inadequate collateral circulation leading to ischemic injury. We believe that transcatheter embolization should be considered an alternative to operative intervention for control of pelvic hemorrhage from gestational trophoblastic disease.
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Franscisco.
authors.forename: M L
authors.initials: ML
authors.lastname: Pearl
authors.forename: C A
authors.initials: CA
authors.lastname: Braga
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D007083:Iliac Artery; D011247:Pregnancy; D014328:Trophoblastic Neoplasms / Q000150:complications* / Q000188:drug therapy; D014592:Uterine Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D014594:Uterine Neoplasms / Q000150:complications* / Q000188:drug therapy