title: [Interaction of proflavin with deoxytetraribonucleoside triphosphate 5'-d(ApGpCpT): thermodynamic analysis from (1)H NMR data].
abstract: Temperature relationships of chemical shifts of protons of proflavin mixed with deoxytetraribonucleoside triphosphate 5'-d(ApGpCpT) in water solution were investigated on impulse NMR spectrometer (500 MHz). Procedure is suggested for calculating values of mole fractions of various associates in solution as a function against temperature. Free energies of Gibbs, entalpy and entropy were determined in the reactions of complex formation 1:1, 1:2, 2:1 of proflavin with tetranucleotide. The results point to a significant role of hydrophobic interactions during the formation of dye--tetramere duplex complexes.
authors.affiliation: Sevastopol Instrument-Making Institute, Burkback College, London University, Great Britain.
authors.forename: A N
authors.initials: AN
authors.lastname: Veselkov
authors.forename: D
authors.initials: D
authors.lastname: Davis
authors.forename: L N
authors.initials: LN
authors.lastname: Dymant
authors.forename: H
authors.initials: H
authors.lastname: Parkes
authors.forename: D
authors.initials: D
authors.lastname: Shipp
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D009843:Oligoribonucleotides / Q000737:chemistry*; D011370:Proflavine / Q000737:chemistry*; D011522:Protons; D013816:Thermodynamics
chemical_list: D009843:Oligoribonucleotides; D011522:Protons; D011370:Proflavine
vernacular_title: Vzaimodeĭstvie proflavina s dezoksitetraribonukleozidtrifosfatom 5'-d(ApGpCpT): termodinamicheskiĭ analiz po dannym (1)H IaMR.