Use of MAC-ELISA for evaluation of yellow fever vaccination.
An evaluation of the IgM antibody immune response against yellow fever using strain 17D was carried out by MAC-ELISA and PRNT. The results showed an agreement of 97% between both tests and the authors conclude that MAC-ELISA can be used as a specific and sensitive assay to replace the PRNT for detecting yellow fever antibodies in human sera, after vaccination programs.
Nogueira
R M
RM
Instituto Oswaldo Cruz, Departamento de Virologia, Rio de Janeiro, Brasil.
Schatzmayr
H G
HG
Miagostovich
M P
MP
Cavalcanti
S M
SM
de Carvalho
R
R
D000914:Antibodies, Viral / Q000097:blood*; D003715:Dengue / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005069:Evaluation Studies as Topic; D006462:Hemolytic Plaque Technique; D006801:Humans; D009500:Neutralization Tests; D014765:Viral Vaccines / Q000276:immunology*; D015004:Yellow Fever / Q000276:immunology; D015005:Yellow fever virus / Q000276:immunology*
D000914:Antibodies, Viral; D014765:Viral Vaccines