title: Focal dermal hypoplasia (Goltz syndrome): report of two cases with minor cutaneous and extracutaneous manifestations.
abstract: Two women, ages 33 and 16 years, had focal dermal hypoplasia (Goltz syndrome) with unusual, minimal clinical manifestations. The lesions consisted of patchy, atrophic, scaly, telangiectatic macules arranged in a linear pattern along Blaschko's lines, involving the anterior and lateral aspects of both legs (patient 1) and the anterolateral aspect of the left leg (patient 2). Type I partial syndactyly involving the second and the third toes in both patients was also present. The clinical and histopathologic features and diagnostic difficulties of cases of this disorder with minimal cutaneous and extracutaneous manifestations are discussed.
authors.affiliation: Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
authors.forename: R M
authors.initials: RM
authors.lastname: Pujol
authors.forename: J M
authors.initials: JM
authors.lastname: Casanova
authors.forename: M
authors.initials: M
authors.lastname: Pérez
authors.forename: X
authors.initials: X
authors.lastname: Matias-Guiu
authors.forename: M
authors.initials: M
authors.lastname: Planagumà
authors.forename: J M
authors.initials: JM
authors.lastname: de Moragas
mesh_terms: D000293:Adolescent; D000328:Adult; D002675:Child, Preschool; D005147:Facial Bones / Q000002:abnormalities / Q000473:pathology; D005260:Female; D005489:Focal Dermal Hypoplasia / Q000235:genetics / Q000473:pathology*; D006801:Humans; D007868:Leg Dermatoses / Q000473:pathology; D008310:Malocclusion / Q000473:pathology; D013576:Syndactyly / Q000473:pathology; D014034:Toes / Q000002:abnormalities