Safety of infectious bursal disease vaccines: assessment of an acceptability threshold.
This study was undertaken to check the safety of commercially available infectious bursal disease (IBD) vaccines in terms of bursal damage, and their immunodepressive effects as evaluated by testing the birds after vaccination for their response to Newcastle disease vaccination. Further requirements are proposed to establish a suitable safety standard.
Guittet
M
M
Centre National d'Etudes Vétérinaires et Alimentaires, Laboratoire Central de Recherches Avicole et Porcine, Ploufragan, France.
Le Coq
H
H
Picault
J P
JP
Eterradossi
N
N
Bennejean
G
G
D000818:Animals; D002060:Bursa of Fabricius / Q000276:immunology / Q000473:pathology; D002645:Chickens; D007108:Immune Tolerance; D007243:Infectious bursal disease virus / Q000276:immunology* / Q000472:pathogenicity; D011201:Poultry Diseases / Q000517:prevention & control; D012088:Reoviridae Infections / Q000517:prevention & control / Q000662:veterinary; D012449:Safety; D014765:Viral Vaccines / Q000009:adverse effects / Q000592:standards*; D014774:Virulence
D014765:Viral Vaccines