title: [Famotidine in the treatment of stomach ulcer].
abstract: In order to evaluate the efficacity and tolerance of Famotidine in the treatment of gastric ulcer, in Lebanese patients, we conducted a prospective open study in twenty one patients with benign gastric ulcer. A clinical, endoscopic and biological evaluation was done before, at 4 weeks and if necessary at 8 weeks after the start of 40 mg of Famotidine per day. All patients were carefully monitored at regular intervals for adverse drug reactions by clinical and biological examinations. The healing rate at 4 and 8 weeks was 75% and 91% respectively. The treatment was well tolerated and no modifications in laboratory tests were observed. Famotidine therefore proved effective in the treatment of gastric ulcer and was well tolerated on a short term basis.
authors.affiliation: Service de Gastroentérologie, Centre Hospitalier Universitaire Hôtel-Dieu de France, Université Saint-Joseph, Beyrouth, Liban.
authors.forename: R
authors.initials: R
authors.lastname: Sayegh
authors.forename: K
authors.initials: K
authors.lastname: Khoury
authors.forename: W
authors.initials: W
authors.lastname: Nassr
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D004361:Drug Tolerance; D015738:Famotidine / Q000627:therapeutic use*; D005260:Female; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain; D011446:Prospective Studies; D013276:Stomach Ulcer / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D014945:Wound Healing
chemical_list: D015738:Famotidine
vernacular_title: La famotidine dans le traitement de l'ulcère gastrique.