title: Fungal 17 beta-hydroxysteroid dehydrogenase.
abstract: Two representatives of each of different fungal taxonomic classes were tested for constitutive 17 beta-hydroxysteroid dehydrogenase (HSDH) activity and the results were positive in all cases. The enzyme was found to be regioselective for C17 of the steroid ring and 20 beta-HSDH activity was only detected in Trichoderma viride. In most cases the oxidative pathway is favoured over the reductive pathway. The possible role of this enzyme in fungi is discussed.
authors.affiliation: Institute of Biochemistry, Medical Faculty, University of Ljubljana, Slovenia.
authors.forename: T
authors.initials: T
authors.lastname: Lanisnik
authors.forename: M
authors.initials: M
authors.lastname: Zakelj-Mavric
authors.forename: I
authors.initials: I
authors.lastname: Belic
mesh_terms: D015067:17-Hydroxysteroid Dehydrogenases / Q000032:analysis* / Q000378:metabolism; D005658:Fungi / Q000201:enzymology*
chemical_list: D015067:17-Hydroxysteroid Dehydrogenases