title: Symptomatic CMV duodenitis. An important clinical problem in AIDS.
abstract: Duodenal disease resulting from cytomegalovirus (CMV) infection is unusual in the absence of other gastrointestinal disease. We report two cases of CMV infection symptomatically isolated to the duodenum. One patient presented with ulcer-type dyspepsia, and the other with severe gastrointestinal bleeding. Ganciclovir therapy resulted in both a clinical and endoscopic remission. The importance of endoscopic evaluation is discussed given the necessity of mucosal biopsy for diagnosis and the availability of specific and effective therapy.
authors.affiliation: Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303.
authors.forename: C M
authors.initials: CM
authors.lastname: Wilcox
authors.forename: D A
authors.initials: DA
authors.lastname: Schwartz
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy; D004382:Duodenitis / Q000150:complications / Q000382:microbiology*; D004415:Dyspepsia / Q000209:etiology; D015774:Ganciclovir / Q000627:therapeutic use; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000150:complications* / Q000188:drug therapy
chemical_list: D015774:Ganciclovir