[Importance of calcium ions and calcium antagonists in affective psychoses].
Apart from the eminent changes in the neurotransmitter systems of the central nervous system, a disturbance of the calcium ion concentration may be of significance in the pathophysiology of affective psychoses. The present paper deals with the contribution of calcium ions in the generation of affective psychoses and discusses the calcium antagonism as a new strategy in the treatment of the disease. The following topics will be described: 1. Disturbances of calcium metabolism in affective psychoses, 2. a comparison of lithium and carbamazepine effects, 3. clinical studies with organic calcium channel blockers in affective psychoses and 4. the role of calcium ions in affective psychoses.
Walden
J
J
Psychiatrische Klinik, Albert-Ludwigs-Universität Freiburg.
Grunze
H
H
Olbrich
H
H
Berger
M
M
D000341:Affective Disorders, Psychotic / Q000188:drug therapy / Q000503:physiopathology* / Q000523:psychology; D001714:Bipolar Disorder / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D002118:Calcium / Q000502:physiology*; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D015220:Calcium Channels / Q000187:drug effects / Q000502:physiology*; D006801:Humans
D002121:Calcium Channel Blockers; D015220:Calcium Channels; D002118:Calcium
Bedeutung von Kalziumionen und Kalziumantagonisten bei affektiven Psychosen.