No evidence for reduced thrombocyte cytochrome oxidase activity in Alzheimer's disease.
We measured cytochrome oxidase activity in thrombocytes from patients with senile dementia of the Alzheimer type. We found no decrease in enzyme activity in Alzheimer's disease patients when compared with patients with multi-infarct dementia, with young control donors, and with age-matched control donors.
Van Zuylen
A J
AJ
Department of Biochemistry, University of Nijmegen, The Netherlands.
Bosman
G J
GJ
Ruitenbeek
W
W
Van Kalmthout
P J
PJ
De Grip
W J
WJ
D000328:Adult; D000544:Alzheimer Disease / Q000097:blood*; D001792:Blood Platelets / Q000201:enzymology*; D002950:Citrate (si)-Synthase / Q000097:blood; D015161:Dementia, Multi-Infarct / Q000097:blood; D003576:Electron Transport Complex IV / Q000097:blood*; D006801:Humans
D003576:Electron Transport Complex IV; D002950:Citrate (si)-Synthase