[Anti-bacterial zeolite balloon catheter and its potential for urinary tract infection control].
We present here a production of anti-bacterial zeolite balloon catheter and investigated its potential for controlling urinary tract infection. This anti-bacterial balloon catheter showed a bactericidal effect against Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli in vitro studies. The antibacterial effects were correlated with the concentration of anti-bacterial zeolite and size of catheter. We tried this catheter for 11 various urological patients who needed a long-term indwelling of a balloon catheter for lower urinary tract obstruction and neurogenic bladder. All patients were already indwelled silicon balloon catheter for 3 to 6 months and suffered with complicated urinary tract infection. Nine patients who had this anti-bacterial zeolite balloon catheter indwelled for 3 to 7 months and exchanged every 2 to 4 weeks, and no patient was taking antibiotics during this trial. Two patients (22.2%) showed good results by the urinary tract infection (UTI) criteria and 5 patients (55.4%) showed good effects by doctor's judgment. This anti-bacterial zeolite balloon catheter might be useful for patients who need long-term balloon catheter indwelling.
Uchida
T
T
Department of Urology, Kitasato University School of Medicine.
Maru
N
N
Furuhata
M
M
Fujino
A
A
Muramoto
S
S
Ishibashi
A
A
Koshiba
K
K
Shiba
T
T
Kikuchi
T
T
D000368:Aged; D000369:Aged, 80 and over; D000538:Aluminum Silicates; D001424:Bacterial Infections / Q000517:prevention & control*; D002404:Catheterization / Q000295:instrumentation*; D002408:Catheters, Indwelling; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014546:Urinary Catheterization / Q000295:instrumentation*; D014552:Urinary Tract Infections / Q000517:prevention & control*; D017641:Zeolites
D000538:Aluminum Silicates; D017641:Zeolites