[A comparative study between broth dilution and agar dilution technics in antibiograms for Candida].
The performance of broth dilution method and agar dilution method were compared by MIC (minimal inhibitory concentration) and MFC (minimal fungicidal concentration) from Candida strains to polyene and imizadole antifungal agents. The concordance between these methods was drug dependent. The best percent of concordance were showed when the polyenes were tested. The problems of sensitivity test for yeasts to antifungal drugs are discussed.
Alves
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SH
Laboratório de Análises Clínicas, Hospital Universitário, Universidade Federal de Santa Maria, Brasil.
Cury
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AE
D000362:Agar; D000935:Antifungal Agents / Q000494:pharmacology; D002175:Candida / Q000187:drug effects*; D003470:Culture Media; D004305:Dose-Response Relationship, Drug; D007093:Imidazoles / Q000494:pharmacology; D008826:Microbial Sensitivity Tests / Q000379:methods; D011090:Polyenes / Q000494:pharmacology
D000935:Antifungal Agents; D003470:Culture Media; D007093:Imidazoles; D011090:Polyenes; D000362:Agar
Estudo comparativo entre as técnicas de diluição em caldo e diluição em ágar, nos antibiogramas para Candida.