title: [The CT-stereotaxic neutron brachytherapy of brain tumors with californium sources on the ANET-B apparatus].
abstract: A method for stereotaxic intratissue radiotherapy of brain tumors based on the findings of computed tomography is described. Radiosurgical implantation of sources with increased 252Cf content emitting mixed neutron + gamma-radiation was accomplished by means of an ANET-B apparatus by the afterloading method. Neutron irradiation is particularly effective in patients with malignant tumors possessing a large fraction of cells in a state of deep anoxia. Dosimetric planning was conducted by means of an original computer system. Devices and radiation-technical equipment for adaptation of the ANET-B apparatus for irradiation of neurosurgical patients are described. The indications for the use of this method and its place among the complex of measures for the treatment of patients with new growths of the brain are discussed. The first experience in using CT-stereotaxic neutron brachytherapy with californium sources on the ANET-B apparatus for the treatment of 6 patients with malignant glial tumors of the brain is dwelt on.
authors.forename: A G
authors.initials: AG
authors.lastname: Melikian
authors.forename: F M
authors.initials: FM
authors.lastname: Liass
authors.forename: F G
authors.initials: FG
authors.lastname: Shkol'nik
authors.forename: V N
authors.initials: VN
authors.lastname: Chekhonadskiĭ
authors.forename: G P
authors.initials: GP
authors.lastname: Elisiutin
authors.forename: A V
authors.initials: AV
authors.lastname: Golanov
authors.forename: I A
authors.initials: IA
authors.lastname: Kachkov
authors.forename: S M
authors.initials: SM
authors.lastname: Borodkin
authors.forename: S A
authors.initials: SA
authors.lastname: Lobanov
authors.forename: O N
authors.initials: ON
authors.lastname: Spasokukotskaia
mesh_terms: D000328:Adult; D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods*; D001921:Brain / Q000000981:diagnostic imaging; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000601:surgery; D002142:Californium / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009502:Neutrons / Q000627:therapeutic use*; D016634:Radiosurgery; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D013238:Stereotaxic Techniques; D014057:Tomography, X-Ray Computed
chemical_list: D002142:Californium
vernacular_title: KT-stereotaksicheskaia neĭtronnaia brakhiterapiia opukholeĭ golovnogo mozga kalifornievymi istochnikami na apparate "ANET-B".