title: Alcoholism in relatives of primary cocaine-dependent patients.
abstract: Inherited susceptibility is believed by some to be a factor in cocaine dependence. In this study, nonalcoholic cocaine-dependent patients (N = 175) were screened to identify alcoholic first-degree relatives. One or more first-degree relatives are also reported to be alcoholic by 25% to 50% of alcoholic patients. Approximately the same percentage of these cocaine patients (34%) also report having an alcoholic first-degree relative. This lends credence to the hypothesis that the apparent inherited susceptibility to alcoholism may be a more general susceptibility to addictive disease. A much higher proportion of females than males have an alcoholic first-degree relative.
authors.affiliation: Schick Shadel Hospital, Seattle, WA 98146.
authors.forename: J W
authors.initials: JW
authors.lastname: Smith
authors.forename: P J
authors.initials: PJ
authors.lastname: Frawley
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000235:genetics* / Q000523:psychology / Q000534:rehabilitation; D016241:Child of Impaired Parents / Q000523:psychology; D003042:Cocaine; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors; D016320:Substance Abuse Treatment Centers; D019966:Substance-Related Disorders / Q000235:genetics* / Q000523:psychology / Q000534:rehabilitation
chemical_list: D003042:Cocaine