Pediatric genitourinary tumors.
Although genitourinary tumors make up only 10% of childhood cancers, with Wilms' tumor accounting for most, the study of these tumors has yielded a model of cancer development. Tremendous interinstitutional and international cooperation has improved the survival and lowered the morbidity of treatment. Advances in molecular biology and improvement in experimental techniques make this a tremendously exciting field, with discoveries being made almost routinely. Most importantly, however, the study of this group of tumors and the ensuing application of multi-modality therapy has saved the lives of thousands of children.
Cowan
B E
BE
Stanford University School of Medicine, California.
Shortliffe
L M
LM
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy / Q000009:adverse effects; D016162:Genes, Wilms Tumor; D006130:Growth Disorders / Q000209:etiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics / Q000628:therapy; D008297:Male; D016609:Neoplasms, Second Primary / Q000453:epidemiology / Q000209:etiology; D012208:Rhabdomyosarcoma / Q000175:diagnosis; D015996:Survival Rate; D013736:Testicular Neoplasms / Q000628:therapy; D014565:Urogenital Neoplasms / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics / Q000628:therapy; D009396:Wilms Tumor / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics / Q000628:therapy