Sarcochromenol sulfates A-C and sarcohydroquinone sulfates A-C, new natural products from the sponge Sarcotragus spinulosus.
New Na+,K(+)-ATPase inhibitors, sarcochromenol sulfates A [1], B [2], and C [3] and sarcohydroquinone sulfates A [4], B [5], and C [6], have been isolated from the sponge Sarcotragus spinulosus. Four of them (1, 4-6) and all six corresponding acetates 1a-6a have been isolated, and their structures have been established by spectral methods and chemical transformations.
Stonik
V A
VA
Laboratory of Marine Natural Products Chemistry, Pacific Institute of Bioorganic Chemistry, USSR Academy of Sciences, Vladivostok.
Makarieva
T N
TN
Dmitrenok
A S
AS
D000818:Animals; D001921:Brain / Q000201:enzymology; D002839:Chromans / Q000302:isolation & purification* / Q000494:pharmacology; D006873:Hydroquinones / Q000302:isolation & purification* / Q000494:pharmacology; D011161:Porifera / Q000737:chemistry*; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors*; D013379:Substrate Specificity
D002839:Chromans; D006873:Hydroquinones; D000254:Sodium-Potassium-Exchanging ATPase