title: Time-dependent increases in Na+,K(+)-ATPase content of low-frequency-stimulated rabbit muscle.
abstract: Chronic low-frequency stimulation of rabbit fast-twitch muscle induced time-dependent increases in the concentration of the sarcolemmal Na+,K(+)-ATPase and in mitochondrial citrate synthase activity. The almost twofold increase in Na+,K(+)-ATPase preceded the rise in citrate synthase and was complete after 10 days of stimulation. We suggest that the increase in Na+,K(+)-ATPase enhances resistance to fatigue of low-frequency-stimulated muscle prior to elevations in aerobic-oxidative capacity.
authors.affiliation: Department of Kinesiology, University of Waterloo, Canada.
authors.forename: H J
authors.initials: HJ
authors.lastname: Green
authors.forename: M
authors.initials: M
authors.lastname: Ball-Burnett
authors.forename: E R
authors.initials: ER
authors.lastname: Chin
authors.forename: L
authors.initials: L
authors.lastname: Dux
authors.forename: D
authors.initials: D
authors.lastname: Pette
mesh_terms: D000818:Animals; D002950:Citrate (si)-Synthase / Q000378:metabolism; D004558:Electric Stimulation; D005260:Female; D008297:Male; D009132:Muscles / Q000201:enzymology* / Q000502:physiology; D011817:Rabbits; D012508:Sarcolemma / Q000201:enzymology; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
chemical_list: D002950:Citrate (si)-Synthase; D000254:Sodium-Potassium-Exchanging ATPase