title: Aspirin-induced urticaria--a clinical study.
abstract: This paper describes the clinical characteristics of patients with aspirin-induced urticaria. The group of 71 patients (49 women and 22 men), with a mean duration of symptoms of 32.5 years, underwent allergological, laryngological and histamine dihydrochloride inhalation tests. Nasal polyps were found in 2 patients (2.8%), atopic disease in 23 (32.3%) and at least one feature of atopy in 37 (51.9%). Forty-nine patients (69%) suffered from urticaria which was not associated with aspirin. In 22 patients, urticaria developed solely due to aspirin. Urticaria not associated with aspirin has been present from 2 weeks to 30 years before the onset of sensitivity to aspirin. The authors conclude that aspirin-induced urticaria results from two different concomitant phenomena, i.e. sensitivity to aspirin and urticaria not associated with ingestion of the drug.
authors.affiliation: Department of Pneumonology and Allergology, Medical Academy of Lódź, Poland.
authors.forename: I
authors.initials: I
authors.lastname: Grzelewska-Rzymowska
authors.forename: M
authors.initials: M
authors.lastname: Szmidt
authors.forename: J
authors.initials: J
authors.lastname: Rozniecki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001241:Aspirin / Q000009:adverse effects*; D016084:Bronchoconstriction / Q000187:drug effects; D004342:Drug Hypersensitivity / Q000150:complications / Q000209:etiology*; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000150:complications; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014581:Urticaria / Q000139:chemically induced* / Q000150:complications / Q000209:etiology
chemical_list: D001241:Aspirin