The relationship of total serum cholesterol to coronary heart disease in older men. The Italian rural areas of the Seven Countries Study.
The relationship of serum cholesterol to the development of major coronary events (CHD) was studied in Italian rural cohorts of adult men aged 40-59 (n = 1672) and of older men aged 65-79 (n = 752) followed up for 5 years. In adult men both univariate and multivariate analysis (the latter with 4 or 5 covariates fed into the Cox model) showed a direct and significant relationship of cholesterol to CHD. In older men the univariate analysis confirmed a direct and significant relationship; for the multivariate analysis none of the considered factors was significantly predictive.
Menotti
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Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy.
D000328:Adult; D000367:Age Factors; D000368:Aged; D002784:Cholesterol / Q000097:blood*; D015331:Cohort Studies; D003327:Coronary Disease / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D012423:Rural Health; D012737:Sex Factors
D002784:Cholesterol