title: Cytologic evidence of the association of different infective lesions with dysplastic changes in the uterine cervix.
abstract: Cervical smears from 4055 women were examined and classified as per WHO criteria. 873 (21.53%) smears revealed dysplastic changes. The dysplastic smears were further examined cytologically for the presence of Chlamydia trachomatis, Herpes simplex virus type-2, Human papilloma virus, Trichomonas vaginalis and Candida albicans. Chlamydia was found to be the commonest micro-organism associated with cervical dysplasia followed by Herpes simplex virus type-2 and Human papilloma virus. The association of Trichomonas and Candida with cervical dysplasia was found to be insignificant. Cervical dysplasia associated with Herpes simplex virus type-2 commonly occurred in the early reproductive life. The data observed in this study provide useful baseline information for detecting the subjects harbouring the infective microbes in the cervical epithelium.
authors.affiliation: Chittaranjan National Cancer Institute, Calcutta, India.
authors.forename: R N
authors.initials: RN
authors.lastname: Chakrabarti
authors.forename: K
authors.initials: K
authors.lastname: Dutta
authors.forename: T
authors.initials: T
authors.lastname: Sarkhel
authors.forename: S
authors.initials: S
authors.lastname: Maity
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002177:Candidiasis / Q000150:complications / Q000453:epidemiology; D002690:Chlamydia Infections / Q000150:complications / Q000453:epidemiology; D005260:Female; D006561:Herpes Simplex / Q000150:complications / Q000453:epidemiology; D006801:Humans; D007239:Infections / Q000150:complications* / Q000382:microbiology; D017533:Marital Status; D008875:Middle Aged; D027383:Papillomaviridae; D010298:Parity; D014247:Trichomonas Vaginitis / Q000150:complications / Q000453:epidemiology; D014412:Tumor Virus Infections / Q000150:complications / Q000453:epidemiology; D002578:Uterine Cervical Dysplasia / Q000150:complications / Q000453:epidemiology / Q000382:microbiology*; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000453:epidemiology; D014626:Vaginal Smears