[The action of amtizol on the plastic properties of the membrane of Retzius' neuron in the leech].
Extracellular application of amtysol decreased the amplitude and increased the duration of evoked APs, not affecting the form of spontaneous APs in the leech Retzius' neurons. Besides, a disorder in the habituation process occurred which only normally develops during a high-frequency synaptic activation of the neurons.
Sergeeva
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D000200:Action Potentials / Q000187:drug effects / Q000502:physiology; D000818:Animals; D002462:Cell Membrane / Q000187:drug effects / Q000502:physiology; D004558:Electric Stimulation; D006185:Habituation, Psychophysiologic / Q000187:drug effects / Q000502:physiology; D066298:In Vitro Techniques; D007865:Leeches / Q000187:drug effects* / Q000502:physiology; D009292:Narcotic Antagonists / Q000494:pharmacology*; D009473:Neuronal Plasticity / Q000187:drug effects* / Q000502:physiology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D013569:Synapses / Q000378:metabolism / Q000502:physiology; D013830:Thiadiazoles / Q000494:pharmacology*
D009292:Narcotic Antagonists; D013830:Thiadiazoles; C044365:amtizol
Issledovanie deĭstviia amtizola na plasticheskie svoĭstva membrany neĭrona Rettsiusa piiavki.