title: [Hepatic carcinoma treated by hepatic arterial embolization using 131I and chemotherapeutic agent gelatin microspheres: report of 9 cases].
abstract: Nine patients with inoperable hepatoma were treated by using hepatic arterial embolization 131I and chemotherapeutic agent gelatin microsphere (131I-CA-GM). The emission CT after operation detected that the microspheres were concentrated on tumor area. The ratio between the radioactivity in tumor and that in liver was 4.1:1. A case died of ictopic embolization; the others survived 3, 4, 5, 19, 24, 7, 8, and 12 months respectively. Three of them were still alive. 131I-CA-GM has triple anticarcinogenic actions, including the arterial occlusion, targeting chemotherapy and internal radiation. The microspheres can selectively accumulate in the tumor artery and can be easily traced by gamma-camera or emission CT. 131I-CA-GM is a hopeful embolic agent for the treatment of liver cancer, but some problems about ectopic arterial embolization should be further studied.
authors.affiliation: Academia Sinica, Chengdu Institute of Organic Chemistry.
authors.forename: X
authors.initials: X
authors.lastname: Chen
authors.forename: Y
authors.initials: Y
authors.lastname: Wu
authors.forename: D
authors.initials: D
authors.lastname: Zhong
authors.forename: L
authors.initials: L
authors.lastname: Li
authors.forename: T
authors.initials: T
authors.lastname: Tan
authors.forename: X
authors.initials: X
authors.lastname: Xie
authors.forename: C
authors.initials: C
authors.lastname: Yan
authors.forename: X
authors.initials: X
authors.lastname: Li
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D004317:Doxorubicin / Q000008:administration & dosage*; D005780:Gelatin / Q000627:therapeutic use; D006499:Hepatic Artery; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008863:Microspheres; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*
chemical_list: D007457:Iodine Radioisotopes; D016685:Mitomycin; D004317:Doxorubicin; D005780:Gelatin