title: [The routine diagnosis of the distal obstructive syndrome (DOS)].
abstract: The diagnosis of distal obstructive syndrome (DOS) is based on the test of lung ventilation function. The tests applied (FEF25-75, MEF50, MEF25) are more sensible than in the routine spirography exploration (FEV1, FEV1.0 x 100/VC), because they evaluate the efficiency of ventilation in those conditions in which the force of the respiratory muscles plays a secondary part and, therefore, cannot hide a flow decrease caused by the obstruction of small pathways (less than 2 mm in diameter). FEF25-75 is measured on the same forced maximum expirogram as FEV1.0. MEF50 and MEF25 are parameters derived from the flow-volume curve. The introduction of these tests into the routine exploration of pulmonary ventilation will improve considerably the diagnosis of early COPD forms.
authors.affiliation: Serviciul de fiziopatologie respiratorie, Institutul de pneumoftiziologie M. Nasta, Bucureşti.
authors.forename: G
authors.initials: G
authors.lastname: Bistriceanu
mesh_terms: D000328:Adult; D003955:Diagnostic Tests, Routine / Q000379:methods*; D005260:Female; D005540:Forced Expiratory Flow Rates; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012129:Respiratory Function Tests / Q000379:methods; D014797:Vital Capacity
vernacular_title: Diagnosticul de rutină al sindromului obstructiv distal (SOD).