[The postradiation effect of acetylcholine and GABA on the active potassium uptake by slices of rat cerebral cortex].
Whole-body X irradiation (0.155 and 0.310 C/kg) was shown to modify the biphase effect of acetylcholine and GABA on antigradient K+ uptake by rat brain sections. Radiation made the effects of neuromediators on active K+ transport be differently directed: acetylcholine enhanced the inhibitory effect of radiation and GABA restored the Na-K-pump function.
Dvoretskiĭ
A I
AI
Anan'eva
T V
TV
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects / Q000528:radiation effects; D002540:Cerebral Cortex / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D008297:Male; D011188:Potassium / Q000378:metabolism / Q000528:radiation effects*; D051381:Rats; D017208:Rats, Wistar; D000254:Sodium-Potassium-Exchanging ATPase / Q000187:drug effects / Q000528:radiation effects; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
D005680:gamma-Aminobutyric Acid; D000254:Sodium-Potassium-Exchanging ATPase; D000109:Acetylcholine; D011188:Potassium
Postradiatsionnyĭ éffekt atsetilkholina i GAMK na aktivnyĭ zakhvat kaliia srezami kory golovnogo mozga krys.