title: [Clinical and histological findings in HCV-caused hepatitis].
abstract: 58 cases of acute HCV-hepatitis were studied from the debut of acute illness and were followed up over 1-12 years. A mean three week's delay of anti-HCV IgG (Ortho) positivity was observed after the first manifestation of hepatitis. 70.6% relapsed and a chronic hepatitis developed in 37.9%. Seven patients died in HCV-hepatitis. Clinical, chemical, morphological features of HCV-hepatitis different from other viral hepatitis are demonstrated. Persistence of morphological signs of lobular hepatitis after even several months of subacute and chronic outcome has been found characteristic in HCV-hepatitis. Difficulties in interpretation of liver morphology are discussed. Simultaneous evaluation of clinical picture, laboratory markers and morphology is necessary to select cases for therapeutic trials.
authors.affiliation: Szent László Kórház, Budapest.
authors.forename: L
authors.initials: L
authors.lastname: Telegdy
authors.forename: M
authors.initials: M
authors.lastname: Kovács
authors.forename: I
authors.initials: I
authors.lastname: Mihály
authors.forename: E
authors.initials: E
authors.lastname: Nagy
authors.forename: E
authors.initials: E
authors.lastname: Csibi
mesh_terms: D000208:Acute Disease; D016174:Hepacivirus / Q000472:pathogenicity; D006526:Hepatitis C / Q000382:microbiology / Q000401:mortality / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology; D009336:Necrosis
vernacular_title: Klinikai és histologiai megfigyeléseink hepatitis C vírus okozta hepatitisben.