[Ultrastructural changes in tumor cell nuclei during spontaneous regression of induced mouse sarcoma virus tumors].
Experimental induction of tumours by mouse sarcoma virus inoculation into the Balb/c mice is a suitable model for following up the mechanisms involved in the regression processes, that is, degradation of tumour cells. Using the electron microscope the analysis of the nucleus of tumour cells in different phases of regression (from 8 to 23 day after inoculation) was performed in order to observe the mechanisms of degradation of tumour cells. It has been concluded that the changes of apoptosis of tumour cells occurred most frequently.
Skaro-Milić
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Vojnomedicinska akademija, Institut za patologiju i sudsku medicinu.
Spasić
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P
D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure*; D051379:Mice; D008807:Mice, Inbred BALB C; D009365:Neoplasm Regression, Spontaneous; D009053:Sarcoma Viruses, Murine; D012513:Sarcoma, Experimental / Q000648:ultrastructure*
Ultrastrukturne izmene nukleusa tumorskih ćelija u toku spontane regresije MSV indukovanih tumora.