Susceptibility of anaerobic bacteria to PD 131628.
The in vitro activity of PD 131628 against anaerobic cocci, Propionibacterium acnes, Clostridium perfringens, Clostridium difficile, Bacteroides fragilis, Bacteroides spp. and fusobacteria was determined by the agar dilution method. This activity was compared with that of ciprofloxacin, piperacillin, cefoxitin, imipenem, clindamycin, metronidazole and chloramphenicol. PD 131628, imipenem, clindamycin, metronidazole and chloramphenicol were the most active agents tested.
Nord
C E
CE
Department of Microbiology, Huddinge University Hospital, Karolinska Institute, Sweden.
Hagelbäck
A
A
D000890:Anti-Infective Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D001441:Bacteroides fragilis / Q000187:drug effects; D016360:Clostridioides difficile / Q000187:drug effects; D003016:Clostridium perfringens / Q000187:drug effects; D024841:Fluoroquinolones; D005673:Fusobacterium / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009287:Naphthyridines; D011425:Propionibacterium acnes / Q000187:drug effects; D015363:Quinolones / Q000494:pharmacology*
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D009287:Naphthyridines; D015363:Quinolones; C068217:PD 131628