[Diagnosis of activity in Crohn's disease and ulcerative colitis: scintigraphy with TC-99m glucoheptonate labelled leukocytes].
We evaluated a pre-tinning leukocyte labeling technique using Glucoheptonate-Sn lyophilized kit, in the detection of activity in 15 patients with clinical and laboratory signs of active inflammatory bowel disease (IBD). 25 patients, without gastrointestinal disease were the control group. In 7/8 patients with Crohn's disease and in 7/7 with Ulcerative Colitis the study was positive. The negative study corresponded to a patient who has only involvement of the duodenum, an area of difficult evaluation due to the high liver uptake. 3/25 patients of the control group had activity in the intestine at 4 hour images. In spite of the small group evaluated, we believe that this labeling technique is a promising procedure for evaluation of activity in patients with IBD (Sensitivity 93.3%, Specificity 88.0%).
Orellana
P
P
Departamento de Radiología, Facultad de Medicina, Pontificia Universidad Católica de Chile.
Ríos
L
L
Gajardo
P
P
Olea
E
E
Oritz
V
V
Nagel
J
J
Quintana
C
C
Gil
M C
MC
D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000000981:diagnostic imaging*; D003424:Crohn Disease / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D013400:Sugar Acids
D015609:Organotechnetium Compounds; D013400:Sugar Acids; C100014:technetium Tc 99m gluceptate
Deteccion de actividad en enfermedad de Crohn y colitis ulcerosa: cintigrafia con leucocitos- TC-99m glucoheptonato.