title: The effect of dietary selenium deficiency on the antioxidant enzyme system in the gastrointestinal tract of the rat.
abstract: The effect of selenium deficiency on the glutathione content and antioxidant enzymes in the gastrointestinal mucosa was studied. It was found that under Se-deficiency the level of glutathione increased, whereas the activity of Se-dependent glutathione peroxidase decreased. The activities of catalase and glutathione-S-transferase were unaffected. Malondialdehyde content was markedly increased in the glandular stomach of Se-deficient rats.
authors.affiliation: Institute of Mother and Child, Department of Biochemistry, Warsawa, Poland.
authors.forename: E
authors.initials: E
authors.lastname: Szymanska
authors.forename: C P
authors.initials: CP
authors.lastname: Siegers
mesh_terms: D000818:Animals; D002374:Catalase / Q000378:metabolism*; D004032:Diet; D004064:Digestive System / Q000201:enzymology* / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism*; D005982:Glutathione Transferase / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000201:enzymology; D007422:Intestines / Q000201:enzymology; D015227:Lipid Peroxidation / Q000187:drug effects; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012643:Selenium / Q000172:deficiency*; D013481:Superoxides / Q000378:metabolism
chemical_list: D008054:Lipid Peroxides; D013481:Superoxides; D008315:Malondialdehyde; D002374:Catalase; D005979:Glutathione Peroxidase; D005982:Glutathione Transferase; D005978:Glutathione; D012643:Selenium; D010100:Oxygen