title: [Secretion of endogenous regulators of Na K ATPase by isolated rat duodenum in osmotic stimulation of its mucous membrane].
abstract: The experiments in vitro have shown that perfusion of the isolated duodenum cavity in rats by hypotonic (20 mosmol/l H2O) or hypertonic (500 mosmol/l H2O) solutions of NaCl and mannitol during 10 min stimulates secretion of endogenic factors (activators or inhibitors of enterocytes of Na+, K(+)-ATPase) into the serous incubation solution. Contact of the duodenum mucose surface with isotonic (300 mosmol/l H2O) solutions does not stimulate the secretion of this enzyme regulators. Endogenic substance are thermostable: they retain activity relative to Na+, K+ ATPase of enterocytes after heating (100 degrees C, 10 min duration) of serous incubation solutions.
authors.forename: M S
authors.initials: MS
authors.lastname: Iaremenko
authors.forename: O M
authors.initials: OM
authors.lastname: Prokopenko
authors.forename: H L
authors.initials: HL
authors.lastname: Vavilova
authors.forename: O M
authors.initials: OM
authors.lastname: Kharlamova
mesh_terms: D000818:Animals; D004386:Duodenum / Q000187:drug effects* / Q000378:metabolism*; D004789:Enzyme Activation / Q000187:drug effects / Q000502:physiology; D007038:Hypotonic Solutions; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism*; D007419:Intestinal Secretions / Q000502:physiology*; D008353:Mannitol / Q000008:administration & dosage / Q000494:pharmacology*; D008954:Models, Biological; D009994:Osmolar Concentration; D051381:Rats; D012462:Saline Solution, Hypertonic; D012965:Sodium Chloride / Q000008:administration & dosage / Q000494:pharmacology*; D000254:Sodium-Potassium-Exchanging ATPase / Q000502:physiology*; D013268:Stimulation, Chemical
chemical_list: D007038:Hypotonic Solutions; D012462:Saline Solution, Hypertonic; D008353:Mannitol; D012965:Sodium Chloride; D000254:Sodium-Potassium-Exchanging ATPase
vernacular_title: Sekretsiia endohennykh reguliatoriv Na+, K+-ATFazy izol'ovanoiu dvanadtsaiatypaloiu kyshkoiu shchuriv pid vplyvom osmotychnoï stymuliatsiï ïï slizovoï obolochki.