title: A longitudinal analysis of factors associated with morbidity in cocaine abusers with psychiatric illness.
abstract: We conducted a study to characterize a population of cocaine users who were referred to a state psychiatric institution, identify treatment problems including reasons for relapse, and develop strategies to improve treatment outcome. Using a data base system from a tertiary-care hospital emergency department, we identified a sample of 80 patients with a cocaine-related presentation who came to the emergency department and were referred to the psychiatric facility. Forty-six percent had consumed crack cocaine, and 65% reported ingesting cocaine with other drugs, half of them with alcohol. Suicidal ideation or attempt was the most common reason for referral. A retrospective review of 58 of the 80 referrals to the psychiatric facility showed that over half of the patients were given a concurrent psychiatric diagnosis and required hospitalization on an acute-care psychiatric unit. Sixty-two percent of those admitted had prior hospitalizations at the psychiatric facility, yet only five patients had received treatment for substance abuse. Seventy-four percent were readmitted to the psychiatric facility within 1 year of their index episode, with a higher rate of relapse among persons with dual diagnoses compared to cocaine users without dual diagnoses (p less than 0.05). Possible reasons for relapse included lack of referral for substance abuse treatment, nonintegrated treatment of psychiatric illness and substance abuse, lack of psychosocial support, and unresolved financial or job-related stressors. The data support increased funding to facilities that treat persons with dual diagnoses, and suggest the need to develop comprehensive treatment approaches involving a multidisciplinary team to address issues of mental illness and substance abuse concomitantly, and to identify and resolve stressors leading to relapse.
authors.affiliation: School of Pharmacy, University of Missouri-Kansas City.
authors.forename: S W
authors.initials: SW
authors.lastname: Stanislav
authors.forename: R W
authors.initials: RW
authors.lastname: Sommi
authors.forename: W A
authors.initials: WA
authors.lastname: Watson
mesh_terms: D000328:Adult; D000359:Aftercare / Q000706:statistics & numerical data; D003042:Cocaine; D003156:Community Mental Health Services / Q000706:statistics & numerical data; D015897:Comorbidity; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data*; D005260:Female; D006778:Hospitals, Psychiatric / Q000706:statistics & numerical data; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D001523:Mental Disorders / Q000150:complications* / Q000628:therapy; D008923:Missouri / Q000453:epidemiology; D010359:Patient Readmission / Q000706:statistics & numerical data; D012017:Referral and Consultation / Q000706:statistics & numerical data; D019966:Substance-Related Disorders / Q000150:complications* / Q000453:epidemiology / Q000628:therapy; D013405:Suicide / Q000523:psychology
chemical_list: D003042:Cocaine