title: Lennert's lymphoma with giant multivesicular lysosomal bodies optically visible.
abstract: A case of a 43-year-old male patient with lymphoepithelioid lymphoma is discussed. During the 10-year follow-up of this patient, different biopsy specimens were obtained. Immunohistochemical studies with a complete paraffin panel determined a T-cell nature of the specimens. Electron microscopy showed a peculiar finding in the cytoplasms of the tumoral cells that correlated with optical inclusions observed in optical imprints; these imprints corresponded to lysosomic multivesicular bodies, whose significance is discussed.
authors.affiliation: Department of Pathology, Fundación Jimenez Diaz, Madrid, Spain.
authors.forename: H
authors.initials: H
authors.lastname: Oliva
authors.forename: C
authors.initials: C
authors.lastname: Rivas
authors.forename: J
authors.initials: J
authors.lastname: Vicente
authors.forename: B
authors.initials: B
authors.lastname: Aguilera
authors.forename: F
authors.initials: F
authors.lastname: Rivas
authors.forename: G
authors.initials: G
authors.lastname: Obeso
authors.forename: M A
authors.initials: MA
authors.lastname: Piris
authors.forename: H
authors.initials: H
authors.lastname: Battifora
mesh_terms: D000328:Adult; D006801:Humans; D002479:Inclusion Bodies / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000648:ultrastructure*; D008247:Lysosomes / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron