Comparison between first- and second-generation test for anti-hepatitis C virus antibodies in hemodialysis patients.
The serum of 387 hemodialysis patients from 9 dialysis units was checked for anti-hepatitis C virus antibodies with a 1st-generation ELISA (Ortho) test: 61 patients were repeatedly positive. In order to avoid false-positive results, these sera were tested with a 1st-generation confirmatory RIBA test, 2nd-generation screening ELISA test and 2nd-generation confirmatory RIBA test. The 2nd-generation ELISA test confirmed data obtained with 1st-generation ELISA, however, the 1st-generation confirmatory RIBA test underestimated the number of anti-HCV-positive patients.
Da Porto
A
A
Department of Nephrology, General Hospital, Treviso, Italy.
Poli
P
P
Calzavara
P
P
Castelletto
M R
MR
Adami
A
A
Cascone
C
C
Amici
G P
GP
Teodori
T
T
Okolicsanyi
L
L
D003951:Diagnostic Errors; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D015151:Immunoblotting / Q000379:methods; D006435:Renal Dialysis / Q000009:adverse effects*
D006508:Hepatitis Antibodies