title: Free radical yields from the homolysis of peroxynitrous acid.
abstract: A recent study reports discordant results for maximal free-radical yields from the decomposition of peroxynitrous acid using different assay reagents and a puzzling decrease (to zero) of the radical yields with increasing pH. An assay method using 2,2,'azino-bis(3-ethyl-benzthiazoline sulphonate) (ABTS) has been tested using stopped-flow kinetic studies, and the results imply that the assay is satisfactory when [HOONO] much greater than [-OONO] but that reactions involving peroxynitrite anion interfere at higher pH. Evidence is presented that peroxynitrite was an interfering species in the earlier studies.
authors.affiliation: Department of Chemistry, University of Newcastle upon Tyne, U.K.
authors.forename: G
authors.initials: G
authors.lastname: Yang
authors.forename: T E
authors.initials: TE
authors.lastname: Candy
authors.forename: M
authors.initials: M
authors.lastname: Boaro
authors.forename: H E
authors.initials: HE
authors.lastname: Wilkin
authors.forename: P
authors.initials: P
authors.lastname: Jones
authors.forename: N B
authors.initials: NB
authors.lastname: Nazhat
authors.forename: R A
authors.initials: RA
authors.lastname: Saadalla-Nazhat
authors.forename: D R
authors.initials: DR
authors.lastname: Blake
mesh_terms: D052160:Benzothiazoles; D005609:Free Radicals; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D007700:Kinetics; D009566:Nitrates / Q000737:chemistry*; D009569:Nitric Oxide / Q000737:chemistry; D013451:Sulfonic Acids; D013481:Superoxides / Q000737:chemistry
chemical_list: D052160:Benzothiazoles; D005609:Free Radicals; D007202:Indicators and Reagents; D009566:Nitrates; D013451:Sulfonic Acids; D013481:Superoxides; C039642:peroxynitric acid; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; D009569:Nitric Oxide