Aniridia-Wilms' tumour syndrome--a case report.
Wilms' tumour is rarely associated with sporadic non-familial congenital aniridia. A child with sporadic aniridia has a 25% chance of subsequently developing Wilms' tumour. Unawareness of this association can lead to a delayed diagnosis of Wilms' tumour. One such case in a 2 year old is reported. Wilms' tumour, one of the common childhood malignancies, is associated with other congenital anomalies in about 15% of cases. These include hemihypertrophy, genitourinary abnormalities, mental retardation, aniridia etc. Sporadic non-familial aniridia was noted in only 1.1% of 547 children with Wilms' tumours evaluated by the National Wilms' Tumour study group. Unawareness on the part of a clinician about these associated anomalies can lead to an avoidable delay in diagnosing Wilms' tumour. One such case in a two year old girl is being reported.
Vidyasagar
M S
MS
Kasturba Medical College & Hospital, India.
Sagar
S V
SV
Kumar
G R
GR
Rao
P
P
D015783:Aniridia / Q000175:diagnosis*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis*; D013577:Syndrome; D009396:Wilms Tumor / Q000175:diagnosis*