[Study on diagnosis of hepatitis A by testing salivary IgM anti-HAV].
The use of salivary samples to diagnose acute hepatitis A was investigated. Result indicated that IgM anti-HAV can be reliably detected in saliva of 58 cases with acute hepatitis A and 9 cases with mixed infection of hepatitis A and B. It is not present in saliva of individuals without recent hepatitis A including 84 cases with acute hepatitis B, 30 cases of hepatitis non A non B and 10 healthy individuals. It was suggested that use of salivary samples to diagnose hepatitis A was specific. It's concluded that saliva is a convenient and satisfactory alternative to serum for the clinical diagnosis and epidemiological investigation of hepatitis A infection.
Wang
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Y
Hangzhou Health and Anti-epidemic Station, Zhejiang Province.
D004797:Enzyme-Linked Immunosorbent Assay; D006506:Hepatitis A / Q000175:diagnosis* / Q000276:immunology; D006508:Hepatitis Antibodies / Q000032:analysis*; D006507:Hepatovirus / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D012463:Saliva / Q000276:immunology*
D006508:Hepatitis Antibodies; D007075:Immunoglobulin M