The gene for the dihydropyridine-sensitive calcium channel alpha 2 subunit (CCHL2A) maps to the proximal region of mouse chromosome 5.
A rat brain cDNA probe for the gene encoding the alpha 2 subunit of the dihydropyridine-sensitive L-type calcium channel was used as a hybridization probe for the Southern blot analysis of Chinese hamster x mouse somatic cell hybrids and the progeny of an intersubspecies backcross. This gene, termed Cchl2a, was mapped near the centromeric end of the Chromosome 5 linkage group with gene order: centromere-Pgy-1-Cchl2a-Il-6-Pgm-1.
Chin
H
H
Laboratory of Molecular Biology, NINDS, National Institute of Health, Bethesda, Maryland 20892.
Mock
B
B
Kim
H L
HL
Kim
H
H
Kozak
C A
CA
D000818:Animals; D015220:Calcium Channels / Q000187:drug effects / Q000235:genetics*; D002874:Chromosome Mapping; D006224:Cricetinae; D003433:Crosses, Genetic; D004247:DNA / Q000235:genetics; D015342:DNA Probes; D004095:Dihydropyridines / Q000494:pharmacology*; D006822:Hybrid Cells; D051379:Mice; D009693:Nucleic Acid Hybridization
D015220:Calcium Channels; D015342:DNA Probes; D004095:Dihydropyridines; C038806:1,4-dihydropyridine; D004247:DNA