[Recurrent cutaneous ecchymoses and hypersensitivity to leukocytic stroma].
A 17-year-old woman presented painful recurrent ecchymoses. Identical lesions were specifically induced by injection of autologous leukocytic stroma. No evidence for possible immunological disturbances was found. Therapy with Nivaquine induced a complete and prolonged remission. The differential diagnosis of this rare form of non-thrombocytopenic purpura, the autosensitization to D.N.A. or to leucocytic stroma, is discussed.
Kalha
E
E
Département d'Hématologie, Hôpital Erasme, Bruxelles.
Van Vooren
J P
JP
De Dobbeleer
G
G
Capel
P
P
D000293:Adolescent; D001323:Autoantibodies / Q000276:immunology*; D002738:Chloroquine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000276:immunology*; D011693:Purpura / Q000188:drug therapy / Q000276:immunology*; D014657:Vasculitis / Q000276:immunology / Q000473:pathology
D001323:Autoantibodies; D002738:Chloroquine
Ecchymoses cutanées récidivantes et hypersensibilité au stroma leucocytaire.