title: [Na K ATPase activity and pulmonary hemodynamics in the development of arterial hypertension].
abstract: A total of 116 subjects with borderline hypertension, 67 relatives of normotensive probands and 29 relatives of hypertensive probands were examined. The activity of Na,K-ATPase in the red blood cells and pulmonary hemodynamics were studied by kinetocardiography. The normotensives with a family history of essential hypertension and subjects with borderline hypertension were found to have elevated pulmonary systolic pressure. The changes were coupled to lower erythrocyte Na,K-ATPase activity, which seems to suggest that endogenous ouabain-like factor that inhibits the enzymatic activity is present in plasma.
authors.forename: M N
authors.initials: MN
authors.lastname: Maslova
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Titkov
authors.forename: L E
authors.initials: LE
authors.lastname: Ogorodnikova
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D004198:Disease Susceptibility; D004912:Erythrocytes / Q000201:enzymology*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology* / Q000235:genetics; D007702:Kinetocardiography; D008297:Male; D011651:Pulmonary Artery / Q000503:physiopathology*; D011652:Pulmonary Circulation / Q000502:physiology*; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood* / Q000172:deficiency
chemical_list: D000254:Sodium-Potassium-Exchanging ATPase
vernacular_title: Aktivnost' Na,K-ATFazy v éritrotsitakh i sostoianie gemodinamiki malogo kruga krovoobrashcheniia pri formirovanii arterial'noĭ gipertonii.