title: Hypercarbia during carbon dioxide gas insufflation for therapeutic laparoscopy: a note of caution.
abstract: During the past decade, the number of laparoscopic procedures performed in the United States, primarily with cholecystectomy, has increased phenomenally. We recently had a patient who developed hypercarbia and cardiovascular compromise during laparoscopic cholecystectomy. The cardiovascular compromise was caused by mechanical factors directly related to increasing intra-abdominal pressures affecting ventilation and venous return as well as the absorption of carbon dioxide (CO2) into the circulation, leading to acidosis and further depression of the cardiopulmonary system. Cardiovascular compromise can be avoided with early recognition of increased end-tidal CO2 concentrations and by preventing intra-abdominal pressures from exceeding 16 mm Hg.
authors.affiliation: Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN 37232.
authors.forename: M
authors.initials: M
authors.lastname: Holzman
authors.forename: K
authors.initials: K
authors.lastname: Sharp
authors.forename: W
authors.initials: W
authors.lastname: Richards
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002245:Carbon Dioxide / Q000008:administration & dosage*; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006935:Hypercapnia / Q000209:etiology*; D007022:Hypotension / Q000209:etiology; D010529:Peritoneal Cavity; D013352:Subcutaneous Emphysema / Q000209:etiology
chemical_list: D002245:Carbon Dioxide