First seizure in adults: to treat or not to treat.
A double-blind trial was done in 228 patients with one single seizure 2 weeks before coming to the author. One group was given sodium valproate, the other group placebo. The duration of therapy was 12 months. The results of this trial show that a person with a single seizure has epilepsy and should be treated with sodium valproate.
Chandra
B
B
Dr. Sutomo Hospital, Airlangga University, Surabaya, Indonesia.
D000293:Adolescent; D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D004569:Electroencephalography / Q000187:drug effects*; D004827:Epilepsy / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012640:Seizures / Q000188:drug therapy* / Q000209:etiology; D014635:Valproic Acid / Q000008:administration & dosage*
D014635:Valproic Acid