[The effect of the lateral hypothalamic area on the pulmonary surfactant system].
The level of lipids, lipase activity and lungs' blood capacity were studied on 62 rats. Dispersal cobalt was infused into the hypothalamic lateral area of rats with adrenalectomy or injected with droperidol, obsidan, reserpine. Their effect upon the hypothalamus involved a decrease in surfactant phospholipids and lung's blood capacity. Possible adrenergic mechanisms of affecting the lung surfactant system are discussed.
Kriuchkova
V I
VI
Lukina
S A
SA
D000315:Adrenalectomy; D000818:Animals; D003037:Cobalt Radioisotopes / Q000008:administration & dosage; D004329:Droperidol / Q000494:pharmacology; D007026:Hypothalamic Area, Lateral / Q000187:drug effects / Q000502:physiology* / Q000528:radiation effects; D008845:Microinjections; D011433:Propranolol / Q000494:pharmacology; D011652:Pulmonary Circulation / Q000187:drug effects / Q000502:physiology / Q000528:radiation effects; D011663:Pulmonary Surfactants / Q000187:drug effects / Q000502:physiology* / Q000528:radiation effects; D051381:Rats; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects / Q000502:physiology / Q000528:radiation effects; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000502:physiology / Q000528:radiation effects; D012110:Reserpine / Q000494:pharmacology
D003037:Cobalt Radioisotopes; D011663:Pulmonary Surfactants; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D012110:Reserpine; D011433:Propranolol; D004329:Droperidol
Vliianie lateral'nogo gipotalamicheskogo polia na surfaktantnuiu sistemu legkikh.