title: Epidemiology of hepatitis C in a population of hemodialysis patients.
abstract: A search for antibodies against hepatitis C virus (HCV) was performed in 185 patients on chronic hemodialysis by means of 1st and 2nd generation ELISA tests. Immunoblot assays were performed on positive sera. This study shows a 38% prevalence of HCV-positive patients in our dialysis population according to the 2nd generation ELISA test which shows a higher specificity and sensitivity when compared to the 1st generation one (38 vs. 20%). A correlation was found between the prevalence of HCV-positive patients and how long they had been on dialysis and how many blood transfusions they had received.
authors.affiliation: Institute of Nephrology, S. Orsola University Hospital, Bologna, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Mosconi
authors.forename: C
authors.initials: C
authors.lastname: Campieri
authors.forename: R
authors.initials: R
authors.lastname: Miniero
authors.forename: L
authors.initials: L
authors.lastname: Colì
authors.forename: C
authors.initials: C
authors.lastname: Orsi
authors.forename: G
authors.initials: G
authors.lastname: La Manna
authors.forename: L B
authors.initials: LB
authors.lastname: De Sanctis
authors.forename: S
authors.initials: S
authors.lastname: Stefoni
authors.forename: G
authors.initials: G
authors.lastname: Sprovieri
authors.forename: V
authors.initials: V
authors.lastname: Bonomini
mesh_terms: D003428:Cross Infection / Q000453:epidemiology / Q000276:immunology / Q000635:transmission; D016174:Hepacivirus / Q000276:immunology; D006508:Hepatitis Antibodies / Q000097:blood; D006526:Hepatitis C / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D006801:Humans; D007558:Italy / Q000453:epidemiology; D006435:Renal Dialysis / Q000009:adverse effects*; D065227:Transfusion Reaction
chemical_list: D006508:Hepatitis Antibodies