title: Malignant fibrous histiocytoma of the auricle: an immunohistochemical and electronmicroscopic study.
abstract: Malignant fibrous histiocytoma (MFH) is a soft-tissue tumor of late adult life. This tumor is uncommon in the head and neck region. A case of MFH arising in the auricle is presented with immunohistochemical and electronmicroscopic findings. Histologically the tumor was characterized by numerous spindle cells with abundant eosinophilic cytoplasm and many small capillaries. They were positively stained with vimentin, alpha 1-antitrypsin, and alpha 1-antichymotrypsin. Electronmicroscopically, some tumor cells contained abundant lysosomes and others contained numerous filaments.
authors.affiliation: Department of Otolaryngology, Tokyo Women's Medical College, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Morita
authors.forename: T
authors.initials: T
authors.lastname: Yoshihara
authors.forename: N
authors.initials: N
authors.lastname: Narita
authors.forename: T
authors.initials: T
authors.lastname: Ishii
authors.forename: M
authors.initials: M
authors.lastname: Aiba
mesh_terms: D000328:Adult; D004424:Ear Canal / Q000473:pathology* / Q000601:surgery; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery