UCT4B, a new antitumor antibiotic with topoisomerase II mediated DNA cleavage activity, from Streptomyces sp.
Kawada
S Z
SZ
Kyowa Hakko Kogyo Co., Ltd., Technical Research Laboratories, Yamaguchi, Japan.
Yamashita
Y
Y
Uosaki
Y
Y
Gomi
K
K
Iwasaki
T
T
Takiguchi
T
T
Nakano
H
H
D000903:Antibiotics, Antineoplastic / Q000032:analysis / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D004250:DNA Topoisomerases, Type II / Q000187:drug effects*; D004224:Diterpenes / Q000032:analysis / Q000494:pharmacology; D005047:Etoposide / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013302:Streptomyces / Q000737:chemistry
D000903:Antibiotics, Antineoplastic; D004224:Diterpenes; C047785:terpentecin; C076481:UCT 4B; D005047:Etoposide; C039027:clerocidin; D004250:DNA Topoisomerases, Type II