[IgA antibodies against Epstein-Barr virus capsid antigen].
The authors describe infection with the Epstein-Barr virus (EBV) which is associated with the formation of various types of antibodies--heterophil (HP) antibodies as well as antibodies against individual EBV antigens. They evaluate the contribution of a recently elaborated and introduced method used for detection of antibodies against the capsid antigen of the EBV class IgA (anti-VCA IgA) by indirect immunofluorescence to the diagnosis of acute and chronic EBV infections. Anti-VCA IgA are useful in the diagnosis of EBV infections if the patient has no longer HP and anti-VCA IgM, but only anti-VCA IgG. If, however, in addition to anti-VCA IgA also anti-VCA IgA are present, their presence can be the only detectable sign of a recent EBV infection and also a sign of reactivation of chronic EBV infection.
Chalupa
P
P
Klinika infekcních chorob lékarské fakulty Masarykovy, univerzity, Brno.
Slesinger
P
P
Krchnáková
A
A
Prásek
J
J
D000328:Adult; D000956:Antigens, Viral / Q000276:immunology*; D002213:Capsid / Q000276:immunology; D036022:Capsid Proteins; D005455:Fluorescent Antibody Technique; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007244:Infectious Mononucleosis / Q000276:immunology; D012680:Sensitivity and Specificity
D000956:Antigens, Viral; D036022:Capsid Proteins; C041788:Epstein-Barr viral capsid antigen; D007070:Immunoglobulin A
Protilátky trídy iga proti kapsidovému antigenu viru Epsteina-Barrové.