title: Prognostic importance of human papillomavirus type 16 DNA in cervical cancer.
abstract: Human papillomavirus (HPV) type 16 DNA is frequent in invasive cervical cancers. Among 43 patients with invasive cervical cancer, HPV-16-positive tumors spread to the parametrial and pelvic lymph nodes significantly more often than did HPV-16-negative tumors (P less than 0.05). Demonstration of HPV-16 DNA in invasive cervical cancers may be an additional prognostic factor for this disease.
authors.affiliation: Department of Obstetrics and Gynecology, University of Graz, Austria.
authors.forename: F
authors.initials: F
authors.lastname: Girardi
authors.forename: P
authors.initials: P
authors.lastname: Fuchs
authors.forename: J
authors.initials: J
authors.lastname: Haas
mesh_terms: D000328:Adult; D000368:Aged; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D027383:Papillomaviridae / Q000235:genetics*; D011379:Prognosis; D014412:Tumor Virus Infections / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000382:microbiology* / Q000473:pathology
chemical_list: D004279:DNA, Viral