[Morphometric analysis of gastric dysplasia and malignancy].
One hundred and eleven specimens of dysplasia and carcinoma of gastric mucosa were studied morphometrically with automatic IBAS image analysis system. A total of 12 parameters of histologic and cellular changes were measured. The results showed that index of structural atypism, gland area, gland perimeter, gland maximum diameter, nucleus-gland ratio index and nuclear area increased in the order of intestinal metaplasia, mild dysplasia, moderate dysplasia, severe dysplasia and carcinoma. These data indicate that computer-assisted morphometry can offer objective criteria in the differential diagnosis of gastric dysplasia and carcinoma.
Shao
L
L
Beijing Medical University.
D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D003937:Diagnosis, Differential; D005753:Gastric Mucosa / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008679:Metaplasia; D011230:Precancerous Conditions / Q000473:pathology*; D013274:Stomach Neoplasms / Q000473:pathology*