[The adrenoreceptor regulation of ureteral contractile function in the guinea pig].
The effects of specific agonists and antagonists of adrenoceptors and inhibitors of cAMP phosphodiesterase on electrostimulated phasic contractions in the ureter of guinea pig were studied. It has been shown that there mainly excitatory alpha 1-adrenoceptors in this object, the density of beta-adrenoceptors is slight and functional alpha 2-adrenoceptors are probably absent. Some aspects of adrenergic regulation of the contractile function of guinea pig ureter are discussed.
Prokopenko
R A
RA
Mohylevych
S Ie
SIe
D000262:Adenylyl Cyclases / Q000187:drug effects / Q000502:physiology; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology*; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects / Q000502:physiology*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000502:physiology*; D014513:Ureter / Q000187:drug effects / Q000502:physiology*
D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D000262:Adenylyl Cyclases
Adrenoretseptorna rehuliatsiia skorochuval'noï funktsiï sechovodu mors'koï svynky.