[Combination of surgery, radiotherapy and chemotherapy for rectal cancer--a 423 cases report].
From June 1975 to June 1985, 423 patients with rectal carcinoma were randomized into 4 groups: 1. Surgery alone (S), 2. Pre-operative radiotherapy plus surgery (RS), 3. Surgery plus postoperative chemotherapy (SC), and 4. Preoperative radiotherapy plus surgery followed by postoperative chemotherapy (RSC). The 5-year survival rates of the combination groups: RS-34.4% (55/160); SC-47.5% (19/40); RSC-52.4%-(33/63) were all superior to that of S alone-28.8% (40/160). The difference between RSC and S alone was particularly significant (P less than 0.01). Further studies are warranted.
Li
R L
RL
Haerbin Medical College Thrid Hospital, Heilogjiang.
D002288:Adenocarcinoma, Mucinous / Q000401:mortality / Q000473:pathology / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000401:mortality / Q000473:pathology / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D015996:Survival Rate