title: A novel subunit ISCOM vaccine against bovine virus diarrhoea virus.
abstract: The preparation and preliminary testing of a subunit ISCOM (immunostimulating complex) vaccine against bovine virus diarrhoea virus (BVDV) is described. Vaccination of calves with this vaccine yields high neutralising titres against a panel of Danish BVDV field isolates. The serological difference between virus isolates and vaccine strain selection is discussed.
authors.affiliation: Ministry of Agriculture, State Veterinary Institute for Virus Research, Kalvehave, Denmark.
authors.forename: S
authors.initials: S
authors.lastname: Kamstrup
authors.forename: L
authors.initials: L
authors.lastname: Rønsholt
authors.forename: M H
authors.initials: MH
authors.lastname: Jensen
authors.forename: K
authors.initials: K
authors.lastname: Dalsgaard
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000517:prevention & control*; D002417:Cattle; D001908:Diarrhea Viruses, Bovine Viral / Q000276:immunology*; D016882:ISCOMs; D014611:Vaccination / Q000662:veterinary*; D014765:Viral Vaccines / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D016882:ISCOMs; D014765:Viral Vaccines