title: [Reactivity of hepatitis C virus (HCV) antibody among blood donors in Hungary].
abstract: The anti-HCV results of 1958 donors are discussed. The Elisa positivity of high risk subjects was as follows: 60% in coagulopathies, 14% in transfused haematological patients and 32% in patients on dialysis. Elisa reactivity of random blood donors was 1.82%, in the group, selected on the basis of transaminase positivity it was over 8%. The confirmed results were compared by the commercially available Elisa tests. 30 positive samples were confirmed by RIBA or Abbott confirmation assay. 35 of the 55 anti-HCV positives were reactive by all the Elisa, 19 samples could be confirmed, 25 were not subjected to any confirmatory assay. Further studies, and the introduction of mandatory screening of blood donors for anti-HCV are necessary.
authors.affiliation: Országos Haematologiai és Vértranszfúziós Intézet, Budapest.
authors.forename: M
authors.initials: M
authors.lastname: Héjjas
authors.forename: G
authors.initials: G
authors.lastname: Medgyesi
authors.forename: A
authors.initials: A
authors.lastname: Hajnal
mesh_terms: D001782:Blood Donors; D004797:Enzyme-Linked Immunosorbent Assay; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000276:immunology*; D006526:Hepatitis C / Q000201:enzymology / Q000276:immunology* / Q000635:transmission; D006801:Humans; D006814:Hungary; D008403:Mass Screening / Q000331:legislation & jurisprudence
chemical_list: D006508:Hepatitis Antibodies
vernacular_title: Hepatitis C vírus (HCV) ellenanyag reaktivitás a hazai véradók körében.