Enteric Clostridium perfringens infection associated with parvoviral enteritis in dogs: 74 cases (1987-1990).
Parvovirus infection was confirmed by fluorescent antibody staining of or viral isolation from specimens of small intestine in 181 (17%) of 1,110 dogs necropsied between July 1, 1987 and Dec 31, 1990. Clostridium perfringens was isolated from 74 (69%) of 108 dogs with parvovirus infection from which specimens of jejunum also had been obtained for culture of anaerobic bacteria. Gram-positive bacilli in association with focal to diffuse necrosis of the superficial portions of the villi were observed in histologic sections of specimens of small intestine from 56 (98%) of 57 dogs from which parvovirus and C perfringens had been identified. These findings indicate that C perfringens frequently proliferates in dogs with parvovirus infection.
Turk
J
J
Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri-Columbia 65205.
Fales
W
W
Miller
M
M
Pace
L
L
Fischer
J
J
Johnson
G
G
Kreeger
J
J
Turnquist
S
S
Pittman
L
L
Rottinghaus
A
A
D000818:Animals; D003015:Clostridium Infections / Q000209:etiology / Q000662:veterinary*; D003016:Clostridium perfringens / Q000302:isolation & purification*; D003967:Diarrhea / Q000150:complications / Q000662:veterinary; D004283:Dog Diseases / Q000209:etiology*; D004285:Dogs; D004751:Enteritis / Q000150:complications / Q000662:veterinary*; D010321:Parvoviridae / Q000302:isolation & purification; D010322:Parvoviridae Infections / Q000150:complications / Q000662:veterinary*; D012189:Retrospective Studies