title: Solubility of inert gases in PFC blood substitute, blood plasma, and mixtures.
abstract: Measurements are reported of the solubility of nonreactive gases, e.g., hydrogen and xenon, in the following liquids: (a) Oxypherol (FC-43 emulsion) blood substitute, (b) blood plasma, (c) mixtures of Oxypherol and blood plasma, and (d) perfluorotributylamine. Typical results for Ostwald solubility at 25 degrees C for Xe gas in various liquids are 0.118 in H2O, 0.12 in blood plasma, and 1.51 in N(C4F9)3. Observed solubilities for the mixtures can be calculated from the relation: L(mixture) = L(emulsion)xv(emulsion) + L (plasma)xv(plasma), in which the v's are the volume fractions in the mixture. This linear relation implies that the gas dissolves independently in each liquid in the mixture. The effect of the emulsifier (Pluronic F-68, 2.6%), on gas solubility in the mixture, is small. Results for the temperature dependence of Ostwald solubility, L(T), in the range 10-37 degrees C are reported.
authors.affiliation: Department of Physics and Astronomy, Michigan State University East Lansing 48824.
authors.forename: G L
authors.initials: GL
authors.lastname: Pollack
authors.forename: R P
authors.initials: RP
authors.lastname: Kennan
authors.forename: G T
authors.initials: GT
authors.lastname: Holm
mesh_terms: D001802:Blood Substitutes; D005466:Fluorocarbons; D006801:Humans; D066298:In Vitro Techniques; D005741:Noble Gases / Q000097:blood*; D010949:Plasma / Q000378:metabolism; D012995:Solubility
chemical_list: D001802:Blood Substitutes; D005466:Fluorocarbons; D005741:Noble Gases; C008807:perfluorotributylamine