title: Increased frequency of HLA-DR3 in Mexican mestizo pediatric patients with amebic liver abscess (ALA).
abstract: Mexican mestizo pediatric patients with ALA revealed a significantly increased frequency of HLA-DR3 alone, or in its haplotype form HLA-A2, DR3, which confirms our previous observation in adult patients with ALA in the same ethnic group. However, the relative increase in these HLA specificities in pediatric ALA patients when compared to adult patients was not statistically significant, and calls for an enlargement of the population studied.
authors.affiliation: Departamento de Immunología y Reumatología INN Dr. Salvador Zubirán SS, UNAM, DF.
authors.forename: J
authors.initials: J
authors.lastname: Arellano
authors.forename: J
authors.initials: J
authors.lastname: Granados
authors.forename: P
authors.initials: P
authors.lastname: Frenk
authors.forename: M
authors.initials: M
authors.lastname: López-Osuna
authors.forename: I
authors.initials: I
authors.lastname: Santos
authors.forename: R R
authors.initials: RR
authors.lastname: Kretschmer
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004198:Disease Susceptibility / Q000276:immunology; D005260:Female; D020022:Genetic Predisposition to Disease; D006680:HLA Antigens / Q000032:analysis; D015789:HLA-A2 Antigen / Q000032:analysis; D015803:HLA-DR3 Antigen / Q000032:analysis*; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D008101:Liver Abscess, Amebic / Q000453:epidemiology / Q000235:genetics* / Q000276:immunology; D008297:Male; D008393:Marriage; D008800:Mexico; D015995:Prevalence; D012307:Risk Factors
chemical_list: D006680:HLA Antigens; D015789:HLA-A2 Antigen; D015803:HLA-DR3 Antigen