Uncommon serious complications in Stevens-Johnson syndrome: a clinical case.
We present an extremely serious clinical case of Stevens-Johnson syndrome, the evolution of which has been followed for 3 years. The etiology was unknown, although it was related with the administration of amoxicillin. We found a type III immunity mechanism involving immune complexes. The serious complications affected the skin, mucosae and internal organs. The present sequelae are: esophageal stenosis, pneumopathy with a 50% deficit of pulmonary perfusion and bilateral trichiasis.
Martín Mateos
M A
MA
Immunology and Allergy Unit, University of Barcelona, Spain.
Polemeque
A
A
Pastor
X
X
Muñoz López
F
F
D000658:Amoxicillin / Q000009:adverse effects; D000936:Antigen-Antibody Complex / Q000378:metabolism; D002675:Child, Preschool; D003165:Complement System Proteins / Q000378:metabolism; D004940:Esophageal Stenosis / Q000150:complications; D005128:Eye Diseases / Q000150:complications; D005140:Eyelashes / Q000473:pathology; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000150:complications / Q000503:physiopathology; D013262:Stevens-Johnson Syndrome / Q000150:complications* / Q000209:etiology / Q000276:immunology; D014692:Ventilation-Perfusion Ratio
D000936:Antigen-Antibody Complex; D000658:Amoxicillin; D003165:Complement System Proteins