title: [Dietary fiber in the dietetic therapy of diabetes mellitus. Experimental data with purified glucomannans].
abstract: In the last years the use of alimentary fibres in dietetic management of diabetic patients increased. The aim of this work was to evaluate, in type 2 diabetic subjects, the glycaemic and insulinemic increments after a standard breakfast with glucomannanos enriched biscuits and with common slices of toast containing the same amounts of carbohydrates and calories. The basal serum values of glucose and C-peptide were similar in the two days of the test. The mean increments of glucose and C-peptide were significantly higher (p < 0.001) after slices of toast than after glucomannanos enriched biscuits. In conclusion our results show a reduction in glycaemic increments after breakfast with glucomannanos-biscuits. The decreased insulin secretion and the reduction of insulin need can longer preserve the functional reserve of beta-cells.
authors.affiliation: Dipartimento di Medicina Interna, Cattedra di Malattie del Ricambio, Università degli Studi di Genova.
authors.forename: P
authors.initials: P
authors.lastname: Melga
authors.forename: M
authors.initials: M
authors.lastname: Giusto
authors.forename: E
authors.initials: E
authors.lastname: Ciuchi
authors.forename: R
authors.initials: R
authors.lastname: Giusti
authors.forename: R
authors.initials: R
authors.lastname: Prando
mesh_terms: D000328:Adult; D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000178:diet therapy*; D004043:Dietary Fiber / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008351:Mannans / Q000627:therapeutic use*; D008875:Middle Aged
chemical_list: D004043:Dietary Fiber; D008351:Mannans; C022901:(1-6)-alpha-glucomannan
vernacular_title: Le fibre alimentari nella terapia dietetica del diabete mellito. Dati sperimentali con glucomannani purificati.