DNA double-strand breaks induced by sparsely ionizing radiation and endonucleases as critical lesions for cell death, chromosomal aberrations, mutations and oncogenic transformation.
Obe
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University GH Essen, Department of Genetics, FRG.
Johannes
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C
Schulte-Frohlinde
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D
D000818:Animals; D016923:Cell Death / Q000528:radiation effects; D002843:Chromatin / Q000648:ultrastructure; D002869:Chromosome Aberrations / Q000235:genetics; D004247:DNA / Q000737:chemistry* / Q000378:metabolism / Q000528:radiation effects*; D004262:DNA Restriction Enzymes / Q000378:metabolism*; D003850:Deoxyribonuclease I / Q000378:metabolism*; D006801:Humans; D009154:Mutation / Q000528:radiation effects; D011839:Radiation, Ionizing; D014170:Transformation, Genetic / Q000528:radiation effects
D002843:Chromatin; D004247:DNA; D004262:DNA Restriction Enzymes; D003850:Deoxyribonuclease I