[Hemoglobin O Arab in Ivory Coast and western Africa].
The authors report 44 cases of hemoglobin O Arab share out in 3 phenotypes (A O Arab, C O Arab and S O Arab). The study of this abnormal hemoglobin has allowed the following conclusions: The Hb O Arab is a rare mutant of hemoglobin. The heterozygote form A O Arab and the association Hb C--Hb O Arab do not present any clinical and hematological manifestations. The associations Hb S--Hb O Arab brings about a serious hemoglobinopathy which has clinical and hematological features like the sickle-cell disease (SSFA2).
Sangare
A
A
Centre Hospitalier Universitaire de Yopougon, Abidjan, Côte d'Ivoire.
Sanogo
I
I
Meite
M
M
Ambofo
Y
Y
Abesopie
V
V
Segbena
A
A
Tolo
A
A
D000293:Adolescent; D000328:Adult; D000354:Africa, Western / Q000453:epidemiology; D001797:Blood Protein Electrophoresis; D002648:Child; D002675:Child, Preschool; D007560:Cote d'Ivoire / Q000453:epidemiology; D005006:Ethnicity; D005260:Female; D006580:Genetic Carrier Screening; D006444:Hemoglobin C; D006453:Hemoglobinopathies / Q000150:complications / Q000453:epidemiology* / Q000235:genetics; D006455:Hemoglobins, Abnormal; D006785:Hospitals, University; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010641:Phenotype; D012737:Sex Factors; D012805:Sickle Cell Trait / Q000150:complications / Q000453:epidemiology
D006455:Hemoglobins, Abnormal; D006444:Hemoglobin C; C032031:hemoglobin Arab
L'hémoglobine o Arab en Côte d'Ivoire et en Afrique de l'Ouest.