Determining the prognosis of childhood epilepsies by establishing immune abnormalities.
When seizures develop in a child, an accurate prediction on outcome of the disorder can hardly be given. Literature indicating an association between seizure disorders and Immunoglobulin (Ig) abnormalities, HLA typing and the occurrence of anti-brain antibodies is shortly reviewed. It is argued that by determining such anti-brain antibodies, early ascertainment of prognosis in seizure disorders may be possible.
Bouma
P A
PA
Department of Neurology, University Hospital, Leiden, The Netherlands.
D000361:Agammaglobulinemia / Q000175:diagnosis / Q000276:immunology; D001323:Autoantibodies / Q000032:analysis*; D001921:Brain / Q000276:immunology; D002648:Child; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis / Q000276:immunology*; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D017098:IgA Deficiency; D007136:Immunoglobulins / Q000032:analysis*; D011379:Prognosis
D001323:Autoantibodies; D006680:HLA Antigens; D007136:Immunoglobulins