The coexistence of stromomyoma and uterine tumor resembling ovarian sex-cord tumors. Report of a case and immunohistochemical study.
The case of a 40-year-old female with a uterine tumor resembling an ovarian sex-cord tumor, located within another neoplastic nodule having the histopathological features of a stromomyoma is reported. Light microscopic examination of the uterine sex-cord-like tumor revealed a highly cellular tumor tissue with no specific differentiation, consisting of solid nests and anastomosing cords and a few pseudo-tubular structures. The vacuolated cytoplasm of the lipid-rich cells proved vimentin-positive, but desmin- and keratin-negative. The coexistence of the two variants of endometrial stromal tumor was interpreted as arising from endometrial stroma or multipotential uterine mesenchyme that showed a diverse differentiation toward ovarian sex-cord stroma and uterine smooth muscle with interspersed stromal cell clusters.
Erhan
Y
Y
Department of Pathology, Ege University School of Medicine, Izmir, Turkey.
Baygün
M
M
Ozdemir
N
N
D000328:Adult; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009214:Myoma / Q000175:diagnosis* / Q000601:surgery; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000601:surgery; D010052:Ovariectomy; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000601:surgery