title: Transgenic approaches to modifying cell and tissue function.
abstract: As our knowledge of cell regulation pathways becomes increasingly sophisticated, the tools and techniques that have emerged from in vitro studies are being applied to the whole organism through transgenesis. With the development of new ways of modifying cellular signalling in intact animals comes the ability to analyse physiological systems and their pathologies with greater spatial and temporal precision.
authors.affiliation: Institute of Molecular and Cell Biology, National University of Singapore.
authors.forename: D
authors.initials: D
authors.lastname: Murphy
authors.forename: D
authors.initials: D
authors.lastname: Carter
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D002460:Cell Line; D002468:Cell Physiological Phenomena; D004195:Disease Models, Animal; D009857:Oncogenes; D011956:Receptors, Cell Surface / Q000235:genetics / Q000502:physiology; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology; D014157:Transcription Factors / Q000235:genetics
chemical_list: D011956:Receptors, Cell Surface; D014157:Transcription Factors