title: Suspected anaphylactoid shock to aminocaproic acid (plaslloid) during operation.
abstract: Epsilon-aminocaproic acid (plaslloid) is one of the most common hemostatics used perioperatively. Although some minor untoward effects in association with its use are not uncommon, the incidence of anaphylactoid shock is extremely rare, especially in a patient under general anesthesia. Recently we came across a severe anaphylactoid reaction, possibly as a result of administration of plaslloid in a patient who was undergoing elective surgery for cervical carcinoma. It was manifested by profound hypotension, tachycardia, hypoxemia, skin-wheel eruption and conjunctival and labial edema. She was successfully resuscitated with prompt volume expansion and epinephrine injection. Our experience in the management of this patient is, hereunder, reported and discussed.
authors.affiliation: Department of Anesthesiology, Veterans General Hospital-Taipei, Taiwan, R.O.C.
authors.forename: H W
authors.initials: HW
authors.lastname: Yien
authors.forename: S S
authors.initials: SS
authors.lastname: Hseu
authors.forename: K H
authors.initials: KH
authors.lastname: Chan
authors.forename: T Y
authors.initials: TY
authors.lastname: Lee
mesh_terms: D015119:Aminocaproic Acid / Q000009:adverse effects*; D000707:Anaphylaxis / Q000139:chemically induced* / Q000628:therapy; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007431:Intraoperative Complications; D008875:Middle Aged; D002583:Uterine Cervical Neoplasms / Q000601:surgery
chemical_list: D015119:Aminocaproic Acid