[Control of homologous recombination by mismatch base repair system in bacteria: implications concerning the chromosome stability and the evolution of species].
The generalized mismatch repair system controls, in bacteria, the homologous recombination between diverged (homologous) DNA. It thus constitute, together with the sequence divergence, a barrier to recombination between bacteria of different species as we have shown for E. coli and S. typhimurium. It is moreover, by preventing the recombination between diverged repeated sequences, a key component of the chromosome stability.
Rayssiguier
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Laboratoire de Mutagenèse, Institut J. Monod, Paris, France.
D005075:Biological Evolution; D002876:Chromosomes, Bacterial / Q000502:physiology; D004260:DNA Repair; D004274:DNA, Recombinant; D004926:Escherichia coli / Q000235:genetics* / Q000648:ultrastructure; D005827:Genetics, Microbial; D066298:In Vitro Techniques; D011995:Recombination, Genetic; D012486:Salmonella typhimurium / Q000235:genetics* / Q000648:ultrastructure; D012689:Sequence Homology, Nucleic Acid
D004274:DNA, Recombinant
Contrôle de la recombinaison homologue par le système de correction des mésappariements de bases chez les bactéries: implications concernant la stabilité chromosomique et l'évolution des espèces.