Blue-gray pigmentation in a patient receiving doxorubicin.
A 64-year-old Japanese female who was treated for hepatocellular carcinoma with doxorubicin developed diffuse blue-gray pigmentation of the face, fading out on the upper trunk. Skin biopsy revealed many melanin granules in the upper dermis. It is believed that the pigmentation was induced by doxorubicin.
Konohana
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Department of Dermatology, Nippon Kokan Hospital, Kawasaki, Japan.
D006528:Carcinoma, Hepatocellular / Q000188:drug therapy; D004317:Doxorubicin / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000139:chemically induced* / Q000473:pathology
D004317:Doxorubicin