[Studies of free radical metabolism in patients with cor pulmonale].
The levels of free radicals in the whole blood of the patients with cor pulmonale were determined using the method of electron spin resonance (ESR). The concentrations of serum SOD were determined using RIA. The concentrations of the MDA, vitamin E, selenium and the activities of the SeGSHPx, CAT of the patients were also measured using biochemical methods. The results showed that the level of free radical in the whole blood and serum MDA, SOD increase if compared with that of control group. The activities of SeGSH-Px, CAT and the concentration of vitamin E in serum of the patients are in lower level. These indicate that there is impairment in free radical metabolism of the patients.
Piao
S F
SF
Second Teaching Hospital of N. Bethune University of Medical Sciences, Chang chun.
D000368:Aged; D002374:Catalase / Q000097:blood; D004578:Electron Spin Resonance Spectroscopy; D005260:Female; D005609:Free Radicals; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D011660:Pulmonary Heart Disease / Q000201:enzymology / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000097:blood
D005609:Free Radicals; D008315:Malondialdehyde; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase