Ca2+ channels: diversity of form and function.
The past year has seen some significant advances in our understanding of the structural and functional properties of neuronal voltage-gated Ca2+ channels. Molecular cloning and protein purification studies have identified structural components, and expression studies are beginning to define the biophysical and pharmacological properties of the cloned channels. A number of studies of native Ca2+ channels show that the concept of channel modulation includes gating by both voltage and ligands.
Snutch
T P
TP
Biotechnology Laboratory, University of British Columbia, Vancouver, Canada.
Reiner
P B
PB
D000818:Animals; D015220:Calcium Channels / Q000502:physiology*; D006801:Humans; D015640:Ion Channel Gating; D009474:Neurons / Q000378:metabolism / Q000502:physiology
D015220:Calcium Channels