[A surprising double tumor of the liver 60 years following thoratrast diagnosis].
A 66-year-old man with thorotrastosis of the reticuloendothelial system is described. Post mortem two tumours were found in an enlarged liver: a cholangiocarcinoma and an angiosarcoma. Coincidentally, a hilar neurofibroma was found. The former two tumours most probably developed because of a lifelong endogenous alpha-irradiation by thorium disintegration. The exceptional latency period of 60 years' duration is emphasized.
Jansen
T L
TL
Afd. Inwendige Geneeskunde, Ziekenhuis Rijnstate, Arnhem.
Meijer
J W
JW
Kesselring
F O
FO
Mulder
C J
CJ
D002759:Adenoma, Bile Duct / Q000209:etiology* / Q000473:pathology; D000368:Aged; D006394:Hemangiosarcoma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology* / Q000473:pathology; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000209:etiology; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D013911:Thorium Dioxide / Q000009:adverse effects*; D013997:Time Factors
D013911:Thorium Dioxide
Een verrassende dubbeltumor van de lever 60 jaar na thorotrast-diagnostiek.