[Antibiotic therapy of intestinal infections complicated by toxicosis and exicosis in children with immunodeficiency syndromes].
Clinical processes of acute intestinal infections complicated by toxicosis and exicosis and some host immunological parameters were studied in infants with secondary immunodeficiency. A special treatment scheme was developed including combined use of antibiotics, human immune globulin administered intravenously and cytochrome C. The scheme provided a decrease in the treatment duration by 8.6 +/- 1.1 days. Advanced and chronic diseases and fatal outcomes were absent. It was concluded that the developed scheme increased host immunological reactivity and efficacy of antibiotic therapy. It was recommended for wide clinical use in pediatric clinical care.
Vereshchagin
I A
IA
Zhabotina
L A
LA
Bukhteeva
E R
ER
Zhuravleva
O D
OD
D000208:Acute Disease; D003131:Combined Modality Therapy; D003574:Cytochrome c Group / Q000008:administration & dosage; D003968:Diarrhea, Infantile / Q000150:complications / Q000276:immunology / Q000628:therapy*; D004760:Enterocolitis / Q000150:complications / Q000276:immunology / Q000628:therapy*; D005839:Gentamicins / Q000008:administration & dosage*; D006801:Humans; D007116:Immunization, Passive; D007153:Immunologic Deficiency Syndromes / Q000150:complications / Q000628:therapy*; D007223:Infant; D011112:Polymyxin B / Q000008:administration & dosage*; D012480:Salmonella Infections / Q000150:complications / Q000276:immunology / Q000628:therapy*; D014031:Tobramycin / Q000008:administration & dosage*; D014115:Toxemia / Q000209:etiology / Q000276:immunology / Q000628:therapy*
D003574:Cytochrome c Group; D005839:Gentamicins; D011112:Polymyxin B; D014031:Tobramycin
Antibiotikoterapiia pri kishechnykh infektsiiakh, oslozhnennykh toksikozom i éksikozom u deteĭ s immunodefitsitnym sostoianiem.