title: Cortical mapping and local anaesthetic resection as an aid to surgery of low and intermediate grade gliomas.
abstract: We report four cases of the use of peroperative cortical mapping during craniotomy under local anaesthesia to define the relationship between the glioma and speech and somatosensory cortex. This enabled a radical subtotal (two cases) or an apparent total (two cases) excision of the tumour close to the somatosensory and speech cortex with no permanent neurological deficit. Use of this technique allows radical excision of intrinsic low and intermediate grade gliomas that would otherwise be considered unexcisable and may lead to an improved survival.
authors.affiliation: Department of Neurosurgery, Atkinson Morley's Hospital, London, UK.
authors.forename: A R
authors.initials: AR
authors.lastname: Walsh
authors.forename: R H
authors.initials: RH
authors.lastname: Schmidt
authors.forename: H T
authors.initials: HT
authors.lastname: Marsh
mesh_terms: D000328:Adult; D000772:Anesthesia, Local; D001254:Astrocytoma / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D001706:Biopsy; D001931:Brain Mapping / Q000295:instrumentation*; D001932:Brain Neoplasms / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D003399:Craniotomy / Q000295:instrumentation; D004558:Electric Stimulation; D004569:Electroencephalography / Q000295:instrumentation*; D005260:Female; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D005909:Glioblastoma / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D009837:Oligodendroglioma / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D010296:Parietal Lobe / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D013238:Stereotaxic Techniques / Q000295:instrumentation