title: [Diurnal variations in circulating leukocytes and subsets: relation to plasma cortisol and ACTH].
abstract: Surface cellular antigens of leukocytes, lymphocytes and corresponding subpopulations have been analysed by using monoclonal antibodies marked with fluorescein (PITC), parallel to those marked with phycoerythrin (PE). Cortisol and ACTH plasmatics have also been determined through RIA, on two samples at 8am. and 8pm. During this twelve hour evolution, a highly significant dependence of the leukocytes, T, T4 and T8 lymphocytes on the circulating ACTH has also been found. In general during the experiment time leukocytes, lymphocytes and subpopulations, have experimented an increase which is significantly related to the pituitary hormone secretion. The existence of this significant correlation establishes the presence of a possible mechanism that connects the cellular immunity to determined hypothalamus hormones.
authors.affiliation: C. S. Virgen de las Nieves, Servicio de Análisis Clínicos, Granada, España.
authors.forename: F
authors.initials: F
authors.lastname: Rodríguez
authors.forename: R E
authors.initials: RE
authors.lastname: Méndez
authors.forename: J A
authors.initials: JA
authors.lastname: Castilla
authors.forename: R
authors.initials: R
authors.lastname: García-Luján
authors.forename: F
authors.initials: F
authors.lastname: Samaniego
authors.forename: J R
authors.initials: JR
authors.lastname: Infante
authors.forename: F
authors.initials: F
authors.lastname: Garrido
authors.forename: F
authors.initials: F
authors.lastname: Perán
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood* / Q000502:physiology; D000328:Adult; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D007958:Leukocyte Count; D016131:Lymphocyte Subsets; D008297:Male; D008875:Middle Aged; D015213:Neuroimmunomodulation / Q000502:physiology; D010913:Pituitary-Adrenal System / Q000502:physiology
chemical_list: D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
vernacular_title: Variaciones diarias en leucocitos y subpoblaciones circulantes: relación con el cortisol y la ACTH plasmáticos.