[ACE Index in patients with respiratory failure].
To investigate whether ACE Index (ACE. Cardiac output-1) which excludes the influence of pulmonary perfusion volume is more useful than angiotensin converting enzyme (ACE) as an early marker of pulmonary endothelial injury and repair, we measured ACE, ACE index, and PaO2.FIO2-1 ratio several times during the stay in the ICU in two patients with respiratory failure. ACE index had a closer relationship to clinical course of respiratory condition and PaO2.FIO2-1 (r = 0.806, 0.889, respectively), in comparison with ACE. We conclude that ACE index could be more sensitive than ACE as an early marker of pulmonary endothelial injury and repair.
Kayaba
M
M
Department of Anesthesiology, Akita University School of Medicine.
Enzan
K
K
Suzuki
M
M
D001784:Blood Gas Analysis; D002302:Cardiac Output; D004730:Endothelium, Vascular / Q000503:physiopathology; D005260:Female; D006801:Humans; D008168:Lung / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D007703:Peptidyl-Dipeptidase A / Q000097:blood*; D012131:Respiratory Insufficiency / Q000175:diagnosis* / Q000503:physiopathology
D007703:Peptidyl-Dipeptidase A