Liver resection for hepatocellular carcinoma in cirrhotic patients.
The results of a multicentric retrospective analysis of 265 liver resections for hepatocellular carcinoma in cirrhotic patients have been collected and assessed. Overall operative mortality was 9.1%. The actuarial 3-year survival was 46.5%. Better results were obtained in patients with encapsulated lesions and alphafetoprotein levels less than 400 ng/dl. Tumoral recurrence, which was the main cause of late death, was related to alphafetoprotein higher levels and to the type of surgery performed: tumor resection with short tumour free margin had the highest recurrence rate. Results were significantly better in those centers where intraoperative ultrasonography was systematically employed.
Gozzetti
G
G
Clinica Chirurgica 2, Policlinico S. Orsola, Milano, Italy.
Belli
L
L
Capussotti
L
L
Di Carlo
V
V
Gennari
L
L
Faccioli
A M
AM
Mazziotti
A
A
Spina
P
P
D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D006509:Hepatitis B / Q000150:complications*; D006801:Humans; D007430:Intraoperative Care; D007558:Italy; D008103:Liver Cirrhosis / Q000150:complications*; D008113:Liver Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000209:etiology* / Q000517:prevention & control; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors; D014463:Ultrasonography