[The involvement of intracellular regulatory systems in the mechanisms of the recovery of the neuronal activity of the cerebral cortex in anoxia].
Changes in the membrane-bound calcium (Ca(b)), polyphosphoinositides (PPI) and cAMP, as well as unit spike activity of the cat brain cortex were studied during 30 min of recovery after 5-min anoxia. The cats with poor recovery revealed low Ca(b) and PPI but high level of the cAMP content. The group of cats with more successful restitution after anoxia revealed a sharp increase in the Ca(b) and PPI and not in the cAMP.
Samoĭlov
M O
MO
Semenov
D G
DG
Tiul'kova
E I
EI
Bolekhan
E A
EA
D000818:Animals; D001923:Brain Chemistry / Q000502:physiology; D002118:Calcium / Q000032:analysis / Q000502:physiology; D002415:Cats; D002462:Cell Membrane / Q000737:chemistry / Q000502:physiology; D002540:Cerebral Cortex / Q000737:chemistry / Q000503:physiopathology*; D000242:Cyclic AMP / Q000032:analysis / Q000502:physiology; D004594:Electrophysiology; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D008839:Microelectrodes; D009474:Neurons / Q000737:chemistry / Q000502:physiology*; D010101:Oxygen Consumption / Q000502:physiology*; D010716:Phosphatidylinositols / Q000032:analysis / Q000502:physiology; D013997:Time Factors
D010716:Phosphatidylinositols; D000242:Cyclic AMP; D002118:Calcium
Vovlechenie vnutrikletochnykh reguliatornykh sistem v mekhanizmy vosstanovleniia aktivnosti neĭronov kory golovnogo mozga posle anoksii.