[The regulation of respiration under the conditions of the altered density of a gaseous environment during muscular work].
In 10 young healthy subjects, both at resting and in muscular work, the substitution of air by a helium-oxygen mixture reduced the central inspiratory drive, the work of breathing, and electrical activity of inspiratory muscles, whereas the inhalation of elegas-oxygen mixture led to obvious opposite effects: the effort for even the least maximal inspiratory flow increased in the same lung ventilation as when breathing air and in constant chemoreceptor stimulus; the central inspiratory activity increased nearly three-fold. The mechanism of the load compensation and of the respiratory system's load seems to be mediated mainly through the afferents from the respiratory muscles' proprioreceptors.
Segizbaeva
M O
MO
Isaeva
G G
GG
D000328:Adult; D000388:Air; D004780:Environment, Controlled; D005080:Exercise Test; D006371:Helium; D006801:Humans; D008297:Male; D010100:Oxygen; D005082:Physical Exertion / Q000502:physiology*; D012119:Respiration / Q000502:physiology*; D012129:Respiratory Function Tests; D015656:Respiratory Mechanics / Q000502:physiology; D012146:Rest / Q000502:physiology; D013997:Time Factors
D006371:Helium; D010100:Oxygen
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