Monitoring of oxidative free radical damage in vivo: analytical aspects.
Free radical damage is an important factor in many pathological and toxicological processes. During the last decade a wide range of methods has been developed to determine free radical damage in various biological fluids and at various stages of development. This review offers an overview of the state of the art of monitoring free radical damage in vivo, with special emphasis on the analytical aspects of non-invasive methods.
Hageman
J J
JJ
Department of Pharmacochemistry, Vrije Universiteit Amsterdam, The Netherlands.
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D000818:Animals; D005609:Free Radicals / Q000009:adverse effects / Q000378:metabolism; D006801:Humans; D006878:Hydroxides / Q000009:adverse effects / Q000378:metabolism; D017665:Hydroxyl Radical; D008991:Monitoring, Physiologic / Q000379:methods; D010084:Oxidation-Reduction; D010100:Oxygen / Q000009:adverse effects / Q000378:metabolism*; D013481:Superoxides / Q000009:adverse effects / Q000378:metabolism
D005609:Free Radicals; D006878:Hydroxides; D013481:Superoxides; D017665:Hydroxyl Radical; D010100:Oxygen