title: UCT4B, a new antitumor antibiotic with topoisomerase II mediated DNA cleavage activity, from Streptomyces sp.
authors.affiliation: Kyowa Hakko Kogyo Co., Ltd., Technical Research Laboratories, Yamaguchi, Japan.
authors.forename: S Z
authors.initials: SZ
authors.lastname: Kawada
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Y
authors.initials: Y
authors.lastname: Uosaki
authors.forename: K
authors.initials: K
authors.lastname: Gomi
authors.forename: T
authors.initials: T
authors.lastname: Iwasaki
authors.forename: T
authors.initials: T
authors.lastname: Takiguchi
authors.forename: H
authors.initials: H
authors.lastname: Nakano
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000032:analysis / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D004250:DNA Topoisomerases, Type II / Q000187:drug effects*; D004224:Diterpenes / Q000032:analysis / Q000494:pharmacology; D005047:Etoposide / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013302:Streptomyces / Q000737:chemistry
chemical_list: D000903:Antibiotics, Antineoplastic; D004224:Diterpenes; C047785:terpentecin; C076481:UCT 4B; D005047:Etoposide; C039027:clerocidin; D004250:DNA Topoisomerases, Type II