title: Aplastic crisis due to human parvovirus B19 infection in hereditary hemolytic anaemia.
abstract: Specific anti-B19 IgM was demonstrated in sera from three children showing transient aplastic crisis. A two years-old boy living in Rio de Janeiro suffering from sickle-cell anaemia showed the crisis during August, 1990. Two siblings living in Santa Maria, RS, developed aplastic crisis during May, 1991, when they were also diagnosed for hereditary spherocytosis. For a third child from this same family, who first developed aplastic crisis no IgM anti-B19 was detected in her sera.
authors.affiliation: Departamento de Virologia, Instituto Oswaldo Cruz, FIOCRUZ, RJ, Brasil.
authors.forename: R C
authors.initials: RC
authors.lastname: Cubel
authors.forename: M C
authors.initials: MC
authors.lastname: Valadão
authors.forename: W V
authors.initials: WV
authors.lastname: Pereira
authors.forename: M C
authors.initials: MC
authors.lastname: Magalhães
authors.forename: J P
authors.initials: JP
authors.lastname: Nascimento
mesh_terms: D000741:Anemia, Aplastic / Q000175:diagnosis / Q000209:etiology*; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000175:diagnosis; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D016731:Erythema Infectiosum / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D016732:Parvovirus B19, Human / Q000276:immunology; D013103:Spherocytosis, Hereditary / Q000150:complications* / Q000175:diagnosis
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M