The distribution of neurons labelled retrogradely with [3H]-D-aspartate injected into the colliculus inferior of the cat.
It is important to know if the transmission of sound signals through the inferior colliculus is mediated by the transmitters glutamate or aspartate because of pharmacological consequences for auditory perception. In order to identify candidate's neurons, the retrograde transport for [3H]-D-aspartate, injected into the left inferior colliculus, was studied in cats. Labelled cells were found in the dorsal and intermediate lateral lemniscal nuclei, mainly on the contralateral side. The cochlear nuclei, superior olivary nuclei and the auditory cortex were not labelled in brains containing other labelled neurons at greater distances from the injection site. Labelled cells were found in the reticular formation and adjacent nucleus coeruleus, the parabrachial nuclei, raphe nuclei (magnus, dorsalis and centralis superior), nucleus prepositus hypoglossi, lateral hypothalamus and hippocampal CA1.
Schwarz
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Rotary Hearing Centre, Division of Otolaryngology, Vancouver, British Columbia, Canada.
Schwarz
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D000818:Animals; D001224:Aspartic Acid / Q000378:metabolism*; D001306:Auditory Pathways / Q000033:anatomy & histology* / Q000000981:diagnostic imaging / Q000378:metabolism; D001933:Brain Stem / Q000000981:diagnostic imaging / Q000378:metabolism; D002415:Cats; D003056:Cochlear Nerve / Q000000981:diagnostic imaging / Q000378:metabolism; D005260:Female; D007245:Inferior Colliculi / Q000000981:diagnostic imaging / Q000378:metabolism*; D007553:Isotope Labeling; D008032:Limbic System / Q000000981:diagnostic imaging / Q000378:metabolism; D008297:Male; D009474:Neurons / Q000000981:diagnostic imaging / Q000378:metabolism*; D011877:Radionuclide Imaging; D009435:Synaptic Transmission / Q000502:physiology*; D014316:Tritium
D014316:Tritium; D001224:Aspartic Acid