title: Cytomegalic inclusion disease presenting acute intrahepatic cholestasis.
abstract: An 83-year-old man suffering from pulmonary emphysema was admitted to our hospital because of jaundice. He was diagnosed as acute intrahepatic cholestasis but the etiology could not be determined during the treatment period. In spite of treatment, the jaundice worsened progressively without any elevation in serum transaminase, and he died of respiratory failure 58 days later. An autopsy revealed a generalized cytomegalic inclusion disease, predominantly in the biliary tracts, liver and lungs. This is a rare case of cytomegalic inclusion disease presenting acute intrahepatic cholestasis without any elevation of transaminase during the clinical course.
authors.affiliation: First Department of Internal Medicine, Matsushita Memorial Hospital, Moriguchi, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Takeuchi
authors.forename: K
authors.initials: K
authors.lastname: Yoshioka
authors.forename: A
authors.initials: A
authors.lastname: Hori
authors.forename: I
authors.initials: I
authors.lastname: Hara
authors.forename: A
authors.initials: A
authors.lastname: Ohsawa
authors.forename: H
authors.initials: H
authors.lastname: Andachi
authors.forename: S
authors.initials: S
authors.lastname: Yokoo
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D001660:Biliary Tract Diseases / Q000175:diagnosis; D002780:Cholestasis, Intrahepatic / Q000175:diagnosis* / Q000201:enzymology; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000201:enzymology / Q000473:pathology; D003937:Diagnosis, Differential; D006525:Hepatitis, Viral, Human / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008297:Male; D011024:Pneumonia, Viral / Q000175:diagnosis / Q000473:pathology; D000637:Transaminases / Q000097:blood
chemical_list: D000637:Transaminases