[Continuous distribution of ventilation-perfusion ratios following lung denervation in dogs by means of inert gas elimination method].
Pulmonary branches of the vagus nerve and sympathetic nerve-chain are severed frequently in thoracic surgery. In this investigation, respiratory function, this transection influence on, was studied, experimentally. Then, denervation of the left lung carried out in mongrel dogs. And distribution of ventilation-perfusion ratio actually present in the lung was measured by multiple inert gases elimination method. In dogs with denervated one side lungs, imbalance of distribution of ventilation-perfusion ratio existed, and it mean that there were areas of high VA/Q in distribution of ventilation. However, there was still no shunt and distribution of blood flow was no dispersion. From the it seems reasonable to infer that blood flow in pulmonary vessel diminished by pulmonary denervation. But arterial blood gas analysis showed normal degree. Accordingly pulmonary gas exchange should not be disturbed to high degree by imbalance of VA/Q distribution due to the denervation.
Oku
H
H
First Department of Surgery, Kurume-University Medical School, Japan.
D000818:Animals; D003714:Denervation / Q000009:adverse effects*; D004285:Dogs; D008168:Lung / Q000294:innervation*; D005741:Noble Gases; D011652:Pulmonary Circulation; D014692:Ventilation-Perfusion Ratio
D005741:Noble Gases