[Image-analysis of salivary tumors].
The image analysis of 49 cases of salivary tumors showed that the cellular DNA content of most tumors (42/49) was diploidy and near diploidy. The heteroploidy rate was only 14.29% (7/49), which may be related to such clinical behaviors of salivary tumors as slow growth, relative low invasivity and metastatic ability. Among these morphologic parameters, nuclear perim and form PE were closely correlated with the malignancy of salivary tumors, the former was positive and the latter was negative. The insignificant nuclear heteromorphous appearance of adenoid cystic carcinoma and its relatively high cellular DNA content may be related to strong invasivity and metastatic ability. In conclusion, these parameters of DNA content and nuclear morphology supplied by image analysis are of value in the diagnosis of salivary tumors.
Zhao
W
W
School of Stomatology, Beijing Medical University.
D000230:Adenocarcinoma / Q000235:genetics; D008949:Adenoma, Pleomorphic / Q000235:genetics / Q000473:pathology; D003536:Cystadenocarcinoma / Q000235:genetics / Q000473:pathology; D004273:DNA, Neoplasm / Q000032:analysis*; D004171:Diploidy; D006801:Humans; D007091:Image Processing, Computer-Assisted; D009361:Neoplasm Invasiveness; D012468:Salivary Gland Neoplasms / Q000235:genetics* / Q000473:pathology
D004273:DNA, Neoplasm