title: [The effect of activation of the superior colliculus on the convulsive activity during picrotoxin-induced kindling].
abstract: Bilateral administration of picrotoxin, bicucullin or benzilpenicillin to the colliculi superior induced high-amplitude hypersynchronous discharges in rats. In these conditions, a suppression of generalized seizures induced with picrotoxin, was observed. The superior colliculi seem to play a significant part in antiepileptic system, the part being realized through generator mechanism.
authors.forename: A A
authors.initials: AA
authors.lastname: Shandra
authors.forename: L S
authors.initials: LS
authors.lastname: Godlevskiĭ
authors.forename: S L
authors.initials: SL
authors.lastname: Vikhrestiuk
authors.forename: A A
authors.initials: AA
authors.lastname: Oleĭnik
mesh_terms: D000818:Animals; D001640:Bicuculline / Q000494:pharmacology; D004569:Electroencephalography / Q000187:drug effects; D007696:Kindling, Neurologic / Q000187:drug effects* / Q000502:physiology; D008297:Male; D008845:Microinjections; D010400:Penicillin G / Q000494:pharmacology; D010852:Picrotoxin / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology; D012640:Seizures / Q000139:chemically induced / Q000503:physiopathology*; D013477:Superior Colliculi / Q000187:drug effects* / Q000502:physiology
chemical_list: D001640:Bicuculline; D010400:Penicillin G; D010852:Picrotoxin
vernacular_title: Vliianie aktivatsii verkhnikh bugorkov chetverokholmiia na sudorozhnuiu aktivnost' pri pikrotoksinovom kindlinge.