title: Cloning and sequence analysis of two embryonic beta-like globin cDNAs (y and z) of hamster.
abstract: A cDNA library was prepared from poly(A) mRNA extracted from 9-day hamster-yolk-sac erythroid cells. Two clones containing inserts coding for embryonic beta-like z or y globin-chains were isolated. Their identity was confirmed by (a) translation of hybrid selected mRNAs and (b) nucleotide sequence analysis of the inserts and comparison to the embryonic beta-like globin genes of Balb/c mouse. Availability of sequences for embryonic and adult globin cDNAs will aid in investigations of the molecular mechanisms of the globin switch in hamster YSEC.
authors.affiliation: Medical Service, St. Luke's-Roosevelt Hospital Center, New York, NY 10025.
authors.forename: H
authors.initials: H
authors.lastname: Li
authors.forename: M
authors.initials: M
authors.lastname: Subar
authors.forename: K M
authors.initials: KM
authors.lastname: Lee
authors.forename: T
authors.initials: T
authors.lastname: Boussios
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D006224:Cricetinae; D004247:DNA / Q000235:genetics*; D004622:Embryo, Mammalian; D005914:Globins / Q000235:genetics*; D008969:Molecular Sequence Data; D012689:Sequence Homology, Nucleic Acid
chemical_list: D005914:Globins; D004247:DNA