A case of adenoid cystic carcinoma of the bronchus producing cancer-associated antigen, CA19-9.
A 73-year-old male was admitted to Hyogo College of Medicine Hospital for further evaluation of chest x-ray abnormalities. Chest roentgenogram taken at admission showed right lower lobe atelectasis and bronchoscopic examination revealed an endobronchial tumor obstructing the left lower lobe bronchus. The biopsy specimen showed cribriform adenoid cystic carcinoma. The serum CA19-9 level was markedly elevated at admission, leading to immunohistochemical analysis of the biopsy specimen. As a result, in the tumor, CA19-9 was positively stained. This is probably the first reported case of adenoid cystic carcinoma of the bronchus which produces CA19-9.
Tamura
S
S
Third Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
Nakano
T
T
Yamaguchi
K
K
Terada
M
M
Maeda
J
J
Iwahashi
N
N
Hada
T
T
Higashino
K
K
D000368:Aged; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000096:biosynthesis* / Q000097:blood; D014408:Biomarkers, Tumor / Q000096:biosynthesis / Q000097:blood; D001984:Bronchial Neoplasms / Q000276:immunology* / Q000473:pathology / Q000628:therapy; D003528:Carcinoma, Adenoid Cystic / Q000276:immunology* / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D005047:Etoposide / Q000627:therapeutic use; D006801:Humans; D007150:Immunohistochemistry; D008297:Male
D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; D005047:Etoposide