title: Hepatic rhabdomyomatous tumor: late sequel of a fetal rhabdomyomatous nephroblastoma.
abstract: A mesenchymal tumor with the macroscopic and microscopic features of a fetal rhabdomyoma arose in the liver of a 14-year-old boy. Thirteen years previously this boy had been treated for a fetal rhabdomyomatous nephroblastoma with nephrectomy and--for subsequent peritoneal disseminations--with surgical excision, radiotherapy, and chemotherapy. The unusual hepatic location of the rhabdomyomatous tumor in this patient supports the view that this mature tumor developed from a metastasis of the original nephroblastoma. As such, this case may represent an example of irreversible change of a malignant process into a benign tumor probably caused by the action of systemic chemotherapy.
authors.affiliation: Department of Pathology, Erasmus University, Rotterdam, The Netherlands.
authors.forename: T H
authors.initials: TH
authors.lastname: van der Kwast
authors.forename: F J
authors.initials: FJ
authors.lastname: ten Kate
authors.forename: V D
authors.initials: VD
authors.lastname: Vuzevski
authors.forename: G C
authors.initials: GC
authors.lastname: Madern
authors.forename: O T
authors.initials: OT
authors.lastname: Terpstra
mesh_terms: D000293:Adolescent; D006801:Humans; D007680:Kidney Neoplasms / Q000378:metabolism / Q000473:pathology*; D008113:Liver Neoplasms / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D008297:Male; D009124:Muscle Proteins / Q000378:metabolism; D016609:Neoplasms, Second Primary / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D012207:Rhabdomyoma / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D013997:Time Factors; D009396:Wilms Tumor / Q000378:metabolism / Q000473:pathology*
chemical_list: D009124:Muscle Proteins