[An analysis of respiratory muscle fatigue under a resistive load with the breathing of gas mixtures with different oxygen levels].
In anesthetized cats, the respiration muscles' fatigue under normoxia occurred in heavy mechanical load equal to 80% of the maximal inspiratory effort. Under hypoxia the force of the diaphragm contraction did never decrease whereas when breathing with hypoxic gas mixture weakening of the contractile ability occurred yet under moderate load. In breathing with additional mechanical load under hypoxia, mainly the peripheral part of the respiratory system's motor apparatus suffers, as the weakening of diaphragm's electrical activity and reduction of its contractions' force occurred during unfalling activity of the diaphragmatic nerve. The oxygen content in arterial blood affects the contractile ability of respiratory muscles. However, the increase in the energy supply level does not necessarily exclude the possibility of respiratory muscles' fatigue, but just decelerates its development.
Aleksandrova
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D000388:Air; D000818:Animals; D002415:Cats; D003964:Diaphragm / Q000503:physiopathology; D004594:Electrophysiology; D005221:Fatigue / Q000503:physiopathology*; D000860:Hypoxia / Q000503:physiopathology; D009119:Muscle Contraction / Q000502:physiology; D010100:Oxygen / Q000008:administration & dosage*; D010791:Phrenic Nerve / Q000503:physiopathology; D015656:Respiratory Mechanics / Q000502:physiology*; D012132:Respiratory Muscles / Q000503:physiopathology*; D013997:Time Factors
D010100:Oxygen
Analiz utomleniia dykhatel'nykh myshts pri rezistivnoĭ nagruzke na fone dykhaniia gazovymi smesiami s razlichnym soderzhaniem kisloroda.