title: [Multiple leiomyosarcomas of extremities].
abstract: Leiomyosarcoma is an uncommon tumor that rarely occurred in extremity. Multiple leiomyosarcomas in different extremities is even rarer. We report a 90 year-old male veteran who was found to have four leiomyosarcomas, one in right arm and the other three in right thigh. The patient sustained gunshot injuries over right thigh and right arm about 60 years ago in a war with severe wound sepsis due to open communited fracture of the femur. These tumors happened to distribute in the vicinity of the old scars. It was speculated that these multicentric tumors were due to decreased immune surveillance caused by aging and induced by the previous trauma. The literatures were reviewed and the diagnostic methods, surgical treatment and the adjuvant therapy were discussed.
authors.affiliation: Plastic and Reconstractive Surgery, VGH-Taichung.
authors.forename: W C
authors.initials: WC
authors.lastname: Chao
authors.forename: P C
authors.initials: PC
authors.lastname: Wang
authors.forename: M
authors.initials: M
authors.lastname: Wen
authors.forename: K C
authors.initials: KC
authors.lastname: Chang
authors.forename: H L
authors.initials: HL
authors.lastname: Wang
mesh_terms: D000368:Aged; D001132:Arm; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology / Q000601:surgery*; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000473:pathology / Q000601:surgery*; D013848:Thigh