HD-Zip proteins: members of an Arabidopsis homeodomain protein superfamily.
Homeobox genes encode a large family of homeodomain proteins in animal systems. To test whether such genes are also abundant in higher plants, degenerate oligonucleotides complementary to sequences encoding the recognition helix (helix three) of the homeodomain were used to screen genomic and cDNA libraries from the plant Arabidopsis thaliana. Analysis of 8 of the 41 cDNAs isolated revealed that each encodes a presumptive homeodomain; interestingly, most of these clones also contain a leucine zipper motif tightly linked to the homeodomain. It is concluded that Arabidopsis encodes a large family of homeodomain proteins, including members that contain a homeodomain/leucine-zipper (HD-Zip) motif.
Department of Biochemistry, Beckman Center, Stanford University Medical Center, CA 94305-5307.
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Schena
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Davis
D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics; D005801:Genes, Homeobox; D017343:Genes, Plant; D016350:Leucine Zippers; D008969:Molecular Sequence Data; D005810:Multigene Family; D015345:Oligonucleotide Probes; D010944:Plants / Q000235:genetics*; D016415:Sequence Alignment
D004268:DNA-Binding Proteins; D015345:Oligonucleotide Probes; D004247:DNA