Fatty acids in lipids of nasoethmoidal polyps.
In 29 samples of recurrent nasoethmoidal polyps removed from 11 patients, the relative fatty acids composition was established by means of gas chromatography. Four samples of nasal mucosa of patients without polyps were subjected to the same procedure. A significant increase in the content of linoleic acid (18:2, n-6) as well as in the index "linoleic acid/oleic acid" was found. Proportion of arachidonic acid was high both in polyps and in control samples of nasal mucosa. An orientation examination of fatty acids in individual fractions of lipids, compared to serum values, showed that the main source of arachidonic acid appears to be phospholipids.
Department of Pathological Physiology, Medical Faculty, Palacký University, Olomouc, Czechoslovakia.
J
J
Hrebícek
P
P
Navrátil
Z
Z
Chmela
J
J
Navrátil
D000328:Adult; D002849:Chromatography, Gas; D005005:Ethmoid Sinus; D005227:Fatty Acids / Q000032:analysis*; D005260:Female; D006801:Humans; D008055:Lipids / Q000032:analysis* / Q000737:chemistry; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000737:chemistry* / Q000601:surgery; D010255:Paranasal Sinus Neoplasms / Q000737:chemistry* / Q000601:surgery; D011127:Polyps / Q000737:chemistry* / Q000601:surgery
D005227:Fatty Acids; D008055:Lipids