Recovery of biocatalysis products from reversed micellar reaction media: a preliminary evaluation of membrane extractors.
It has been demonstrated that ultrafiltration membranes of sufficiently low molecular weight cutoff can be used to retain reversed micelles and their hosted enzymes, while permitting the recovery of lipophilic products of enzymatically-catalysed, synthesis reactions in a stripping solution on the other side of the membrane. Calculations indicate that hollow fibre membranes having the same rejection characteristics and solvent resistance as the flat sheet membranes, will provide an attractive and efficient means for the recovery of these biosynthesis products; currently, such membrane modules are not available commercially.
Luthi
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Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge 02139.
Hatton
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D004798:Enzymes / Q000302:isolation & purification*; D008567:Membranes, Artificial; D008823:Micelles
D004798:Enzymes; D008567:Membranes, Artificial; D008823:Micelles