[The diagnosis of cryptococcosis. A comparison of 2 latex systems for antigen detection].
A latex reactive was designed for detecting Cryptococcus neoformans antigen. It was evaluated by a comparative study with a commercial system (Meridian Diagnostic, Inc.). Total coincidence was observed with both latex systems after studying 3 sample groups: patients with cryptococcosis diagnosis, blood bank donors and patients with clinical signs of the disease. Sensitivity, specificity and stability of the latex reactives prepared were assessed. This diagnostic technique opens new perspectives for quick diagnosis in Cuba, especially for immunosuppressed patients. It will allow for timely treatment and at the same time will contribute to saving expenses in imports.
Alvarez Bernal
L P
LP
Laboratorio de Micología, Instituto de Medicina Tropical Pedro Kourí.
Martínez Machín
G
G
Fernández Andreu
C
C
Llop Hernández
A
A
D000946:Antigens, Fungal / Q000097:blood*; D001782:Blood Donors; D003453:Cryptococcosis / Q000175:diagnosis*; D003455:Cryptococcus neoformans / Q000276:immunology*; D003462:Cuba; D005069:Evaluation Studies as Topic; D006801:Humans; D007841:Latex Fixation Tests / Q000379:methods*; D012680:Sensitivity and Specificity
D000946:Antigens, Fungal
Diagnóstico de criptococosis. Comparación de 2 sistemas de látex para la detección de antígeno.