Receptor-based assays.
Receptor-based assays have benefitted from the newest advances in biotechnology and electronics in three main ways: genetically engineered cells expressing single receptor subtypes have been developed for many natural and synthetic ligands; assays have been designed which take advantage of a variety of signals triggered in cells by binding, or inhibition of binding, of ligands to surface-bound receptors; and radiolabelled ligand assays have been considerably improved and simplified by novel electronic devices.
CNRS, Université Paris VII, Institut Cochin de Génétique Moléculaire, France.
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Strosberg
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Leysen
D000818:Animals; D001610:Beta Particles; D005374:Filtration; D006801:Humans; D008024:Ligands; D010766:Phosphorylation; D011956:Receptors, Cell Surface / Q000032:analysis* / Q000235:genetics / Q000276:immunology; D014443:Tyrosine / Q000378:metabolism
D008024:Ligands; D011956:Receptors, Cell Surface; D014443:Tyrosine