Effect of compressional forces on piroxicam polymorphs.
The effect of compressional force on the polymorphic transition in piroxicam has been examined, using pure polymorph, by differential scanning calorimetry, powder X-ray diffractometry and by determination of dissolution rates from tablets of the individual polymorphs. The needle shaped polymorph was found to undergo transition to the cubic polymorph during compression.
K. M. Kundnani College of Pharmacy, Plot No. 47, Worli, Bombay, India.
G A
GA
Ghan
J K
JK
Lalla
D010894:Piroxicam / Q000737:chemistry*; D011312:Pressure; D012995:Solubility; D014961:X-Ray Diffraction
D010894:Piroxicam