Molecular biological approaches to genetic disorders in prenatal diagnosis.
DNA analysis of Duchenne muscular dystrophy (DMD) and hemophilia A was performed with the aim of establishing the most efficient and reliable method for carrier and prenatal diagnosis in the Japanese population.
Katayama
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First Department of Obstetrics and Gynecology, School of Medicine, Toho University, Tokyo, Japan.
D015139:Blotting, Southern; D004247:DNA / Q000235:genetics*; D015342:DNA Probes; D005260:Female; D006580:Genetic Carrier Screening / Q000379:methods; D008040:Genetic Linkage; D006467:Hemophilia A / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D009136:Muscular Dystrophies / Q000175:diagnosis* / Q000235:genetics; D010375:Pedigree; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D015203:Reproducibility of Results; D014960:X Chromosome
D015342:DNA Probes; D004247:DNA