Regional localization of three convertases, PC1 (Nec-1), PC2 (Nec-2), and furin (Fur), on mouse chromosomes.
The genes for three convertases, PC1 (Nec-1), PC2 (Nec-2), and furin (Fur), have been regionally localized on chromosomes 13, 2, and 7, respectively, by interspecific backcross analysis. These results refine previous localizations by in situ hybridization as well as confirm and extend known regions of homology between mouse and human chromosomes.
Copeland
N G
NG
Mammalian Genetics Laboratory, ABL-Basic Research Program, NCI-Frederick Cancer Research and Development Center, Maryland 21702.
Gilbert
D J
DJ
Chrétien
M
M
Seidah
N G
NG
Jenkins
N A
NA
D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D045683:Furin; D051379:Mice; D008810:Mice, Inbred C57BL; D012150:Polymorphism, Restriction Fragment Length; D013381:Subtilisins / Q000235:genetics*
D013381:Subtilisins; D045683:Furin