Families of twelve transmembrane domain transporters.
Several functionally distinct families of transport proteins share the general structural motif of twelve transmembrane domains. The number of membrane proteins known to possess this common feature continues to expand with the cloning of transporters for various neurotransmitters, nucleosides, osmolytes and basic amino acids, in addition to the previously defined families of facilitative and sodium-driven sugar transporters.
Vollum Institute, Oregon Health Sciences University, Portland 97201.
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Kilty
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Amara
D000818:Animals; D001692:Biological Transport; D001693:Biological Transport, Active; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism; D050483:Dopamine Plasma Membrane Transport Proteins; D050485:GABA Plasma Membrane Transport Proteins; D006801:Humans; D008562:Membrane Glycoproteins; D008565:Membrane Proteins / Q000737:chemistry / Q000378:metabolism; D026901:Membrane Transport Proteins; D009004:Monosaccharide Transport Proteins / Q000378:metabolism; D009419:Nerve Tissue Proteins; D027361:Organic Anion Transporters; D017433:Protein Structure, Secondary; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D002352:Carrier Proteins; D050483:Dopamine Plasma Membrane Transport Proteins; D050485:GABA Plasma Membrane Transport Proteins; D008562:Membrane Glycoproteins; D008565:Membrane Proteins; D026901:Membrane Transport Proteins; D009004:Monosaccharide Transport Proteins; D009419:Nerve Tissue Proteins; D027361:Organic Anion Transporters; D005680:gamma-Aminobutyric Acid; D004298:Dopamine