Changes in vitreous humor associated with postmortem interval in rabbits.
Concentrations of serum and vitreous humor constituents at time of death, and concentrations of vitreous humor constituents at time of death and at 7 postmortem intervals were compared in 70 domestic, female New Zealand White rabbits (Oryctolagus cuniculus). Urea nitrogen concentration was significantly (P = 0.0094) different, but was linearly correlated in serum and vitreous humor at time of death and at the 4- and 8-hour postmortem intervals. Concentrations of gamma-glutamyltransferase were not significantly different in serum and vitreous humor at time of death, nor were concentrations significantly different in vitreous humor at time of death and at the 4-hour postmortem interval. The vitreous humor concentrations of glucose, triglycerides, sodium, potassium, cholesterol, total protein, albumin, lactate dehydrogenase, creatine kinase, aspartate transaminase, bilirubin, cortisol, and IgG were neither similar to nor predictive of serum constituents. Vitreous humor can be used as a source for estimates of serum urea nitrogen and gamma-glutamyltransferase up to 8 and 4 hours after death, respectively.
Department of Range and Wildlife Management, Texas Tech University, Lubbock 79409.
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Henke
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Demarais
D000418:Albumins / Q000032:analysis; D000818:Animals; D001219:Aspartate Aminotransferases / Q000032:analysis / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D001798:Blood Proteins / Q000032:analysis; D002784:Cholesterol / Q000032:analysis / Q000097:blood; D003402:Creatine Kinase / Q000032:analysis / Q000097:blood; D005136:Eye Proteins / Q000032:analysis; D005260:Female; D005947:Glucose / Q000032:analysis; D007770:L-Lactate Dehydrogenase / Q000032:analysis / Q000097:blood; D011180:Postmortem Changes; D011188:Potassium / Q000032:analysis / Q000097:blood; D011817:Rabbits / Q000378:metabolism*; D012709:Serum Albumin / Q000032:analysis; D012964:Sodium / Q000032:analysis / Q000097:blood; D014280:Triglycerides / Q000032:analysis / Q000097:blood; D014508:Urea / Q000032:analysis / Q000097:blood; D014822:Vitreous Body / Q000737:chemistry / Q000201:enzymology / Q000473:pathology*; D005723:gamma-Glutamyltransferase / Q000032:analysis / Q000097:blood
D000418:Albumins; D001786:Blood Glucose; D001798:Blood Proteins; D005136:Eye Proteins; D012709:Serum Albumin; D014280:Triglycerides; D014508:Urea; D002784:Cholesterol; D012964:Sodium; D007770:L-Lactate Dehydrogenase; D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase; D005947:Glucose; D011188:Potassium