Juvenile myoclonic epilepsy of Janz: clinical observations in 60 patients.
We studied 60 patients with juvenile myoclonic epilepsy (JME). There was a high positive family history for epilepsy (33.3%). Age at onset of epilepsy ranged from 4 to 18 years with an average of 13.9 years. 88.3% of patients were seizure-free. The most effective drug was valproate. In eight patients drug withdrawal was attempted but all patients relapsed during a follow-up period of 1 year. Video-EEG studies were performed in eight newly diagnosed patients; myoclonic jerks were recorded in five patients.
University of Milan, Chair of Clinical Neurophysiology, S. Paolo Hospital, Italy.
M P
MP
Canevini
R
R
Mai
C
C
Di Marco
C
C
Bertin
L
L
Minotti
V
V
Pontrelli
A
A
Saltarelli
R
R
Canger
D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage; D002540:Cerebral Cortex / Q000503:physiopathology; D004569:Electroencephalography / Q000187:drug effects; D004831:Epilepsies, Myoclonic / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology; D004832:Epilepsy, Absence / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology; D004830:Epilepsy, Tonic-Clonic / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation; D017286:Polysomnography; D014741:Video Recording
D000927:Anticonvulsants