[The characteristics of the effect of mediator substances on the dynamic oxygen tension in the gastric mucosa].
The studies on rats were carried out to determine dynamics of pO2 in the mucous membrane of the stomach under the effect of acetylcholine, norepinephrine, serotonin, histamine, prostaglandin E2 and ATP. As to the changes in pO2 the mediator substances were arranged as follows (from more intensive effect to less pronounced one): serotonin, acetylcholine, prostaglandin E2, norepinephrine, histamine and ATP. As to the duration of the action--PGE2 acetylcholine, serotonin, norepinephrine, ATP and histamine. Under the joint action of the mediator substances (serotonin, norepinephrine, histamine) with acetylcholine the effects of domination and modulation of acetylcholine effect are found.
A Ia
AIa
Skliarov
D000818:Animals; D004347:Drug Interactions; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D018377:Neurotransmitter Agents / Q000494:pharmacology*; D010101:Oxygen Consumption / Q000187:drug effects*; D010313:Partial Pressure; D051381:Rats; D013997:Time Factors
D018377:Neurotransmitter Agents
Kharakteristika vliianiia mediatornykh veshchestv na dinamiku napriazheniia kisloroda v slizistoĭ obolochke zheludka.