PrPSc causes nerve cell death and stimulates astrocyte proliferation: a paradox.
DeArmond
S J
SJ
Department of Pathology, University of California, San Francisco 94143-0506.
Kristensson
K
K
Bowler
R P
RP
D000818:Animals; D001253:Astrocytes / Q000187:drug effects* / Q000378:metabolism; D001920:Bradykinin / Q000494:pharmacology; D002118:Calcium / Q000494:pharmacology; D015220:Calcium Channels / Q000187:drug effects / Q000378:metabolism; D016923:Cell Death / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D006224:Cricetinae; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D005911:Gliosis / Q000209:etiology / Q000473:pathology; D006801:Humans; D007700:Kinetics; D008647:Mesocricetus; D051379:Mice; D009447:Neuroblastoma; D009474:Neurons / Q000187:drug effects* / Q000473:pathology; D010982:Platelet-Derived Growth Factor / Q000494:pharmacology; D018620:PrPSc Proteins; D017096:Prion Diseases / Q000150:complications / Q000473:pathology*; D011328:Prions / Q000235:genetics / Q000378:metabolism / Q000494:pharmacology*; D011499:Protein Processing, Post-Translational; D012608:Scrapie / Q000378:metabolism / Q000473:pathology; D014407:Tumor Cells, Cultured
D015220:Calcium Channels; D005904:Glial Fibrillary Acidic Protein; D010982:Platelet-Derived Growth Factor; D018620:PrPSc Proteins; D011328:Prions; D001920:Bradykinin; D002118:Calcium