Efficacy of bi-annual administration of DEC in the control of bancroftian filariasis.
The efficacy of bi-annual administration of DEC at the dose of 6 mg/kg body weight was evaluated on the microfilaraemia prevalence, density and vector filarial infection rates. Administration of four doses (4 x 6 mg/kg) of DEC significantly (P < 0.05) reduced the microfilaria rate of the community from 6.02 per cent to 2.31 per cent, microfilaria density from 0.66 to 0.17 and infectivity rate of the vector population from 0.8 per cent to 0.39 per cent.
Vector Control Research Centre, Indira Nagar, Pondicherry.
N
N
Balakrishnan
K D
KD
Ramaiah
S P
SP
Pani
D000818:Animals; D001835:Body Weight; D003465:Culex / Q000254:growth & development / Q000469:parasitology; D004049:Diethylcarbamazine / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004341:Drug Evaluation; D004605:Elephantiasis, Filarial / Q000097:blood / Q000453:epidemiology / Q000469:parasitology / Q000517:prevention & control*; D006801:Humans; D007194:India / Q000453:epidemiology; D007303:Insect Vectors / Q000254:growth & development / Q000469:parasitology; D015995:Prevalence; D016036:Seroepidemiologic Studies; D014958:Wuchereria bancrofti
D004049:Diethylcarbamazine