Tardive dyskinesia and type II schizophrenia.
Cognitive impairment, negative and positive symptoms, primitive release reflexes, and age/temporal disorientation were assessed in 20 male patients meeting the DSM-III-R criteria for chronic schizophrenia and Schooler & Kane's criteria for TD. The control group comprised 20 age-matched male chronic schizophrenic patients without TD. Significant associations were found between TD, cognitive impairment, some negative symptoms, and formal thought disorder. These associations were independent of other illness and treatment variables. The severity of TD correlated significantly with that of cognitive impairment.
Davis Institute of Neuropsychiatry, Ranchi, India.
E J
EJ
Davis
M
M
Borde
L N
LN
Sharma
D000367:Age Factors; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002908:Chronic Disease; D003072:Cognition Disorders / Q000139:chemically induced / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D004409:Dyskinesia, Drug-Induced / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009949:Orientation; D011569:Psychiatric Status Rating Scales; D012018:Reflex / Q000502:physiology; D012559:Schizophrenia / Q000188:drug therapy* / Q000503:physiopathology; D012565:Schizophrenic Psychology; D013998:Time Perception
D014150:Antipsychotic Agents