Mouse models of human diseases.
Cancer, poliomyelitis, Alzheimer's and Gaucher disease, a seemingly disparate array of disorders, have become the target of powerful genetic analysis and drug screening protocols, using mouse strains that have been genetically altered to serve as models for understanding the disease and for helping the patient.
Westphal
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Laboratory of Mammalian Genes and Development, National Institute of Child Health and Human Development, National Institute of Health, Bethesda, MD 20892.
D000544:Alzheimer Disease / Q000235:genetics*; D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D009374:Neoplasms, Experimental / Q000235:genetics*; D011051:Poliomyelitis / Q000235:genetics*