Three types of binding by Porphyromonas gingivalis and oral bacteria to fibronectin, buccal epithelial cells and erythrocytes.
This study showed that the interaction of oral bacteria with fibronectin differed with the type of organism examined. Significant binding of fibronectin was found with Porphyromonas gingivalis non-fimbriated (F-) strain in comparison with the fimbriated strain (F+). However, the F+ strain adhered to buccal epithelial cells in significantly larger numbers than the F- strain. Fibronectin binding and epithelial cell adherence were not associated with haemagglutinating activity. These assays clearly define at least three distinct types of binding by oral bacteria: to fibronectin, buccal epithelial cells and erythrocytes.
Department of Preventive Dentistry, School of Dentistry, Higashi Nippon Gakuen University, Hokkaido, Japan.
E
E
Isogai
K
K
Hirose
N
N
Fujii
H
H
Isogai
D018829:Adhesins, Bacterial; D001422:Bacterial Adhesion / Q000502:physiology*; D001426:Bacterial Proteins / Q000378:metabolism; D005353:Fibronectins / Q000378:metabolism*; D010861:Fimbriae, Bacterial / Q000502:physiology; D016966:Porphyromonas gingivalis / Q000502:physiology*; D011485:Protein Binding; D017469:Receptors, Fibronectin; D011971:Receptors, Immunologic / Q000378:metabolism
D018829:Adhesins, Bacterial; D001426:Bacterial Proteins; D005353:Fibronectins; D017469:Receptors, Fibronectin; D011971:Receptors, Immunologic; C063910:adhesin, Bacteroides