[Morphometric investigations of rat parotid gland after experimental encortone treatment].
The influence of Encortone treatment in the dose of 1 mg/kg of body mass on the secretory segments of male rat parotid gland was investigated. The changes of section area of cell nuclei, secretory cells, serous acini and changes of the number of cells in the acini were statistically analyzed. The observed changes depended upon the period of Encortone treatment. Seven-day Encortone treatment caused a statistically significant increase of the cell nuclei size and decrease of the cell and acini sizes. Changes of these parameters were result of cell hyperplasia and formation of new acini. Thirty-day Encortone treatment caused hypertrophy of cell nuclei, cells and acini of rat parotid.
Katedra i Zakład Histologii i Embriologii z Pracownia Cytologii Doświadczalnej, Akademia Medyczna w Lublinie.
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Zarebska
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Królikowska-Prasał
D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects; D006984:Hypertrophy / Q000139:chemically induced; D008297:Male; D010306:Parotid Gland / Q000187:drug effects* / Q000473:pathology*; D011241:Prednisone / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar
D011241:Prednisone
Morfometryczne badania przyusznicy szczura po doświadczalnym podawaniu Encortonu.