Comparison of the adrenocorticotropic hormone stimulation test in the follicular and luteal phases of the menstrual cycle.
A comparison was made of the ACTH stimulation test in the proliferative and luteal phases of the menstrual cycle in 13 subjects, each of whom served as her own control. The test yielded a 53.9% false-positive rate in the luteal phase. The study, therefore, clearly shows that from a practical, clinical point of view, the test is completely unreliable in the luteal phase, and is only valid when carried out in the follicular phase of the cycle.
Department of Obstetrics and Gynecology, Queens Hospital Center, Albert Einstein College of Medicine, Bronx, New York.
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Harracksingh
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Benjamin
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Deutsch
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Seltzer
D019326:17-alpha-Hydroxyprogesterone; D000312:Adrenal Hyperplasia, Congenital / Q000175:diagnosis*; D000324:Adrenocorticotropic Hormone; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D005498:Follicular Phase / Q000502:physiology*; D006801:Humans; D006908:Hydroxyprogesterones / Q000097:blood; D008183:Luteal Phase / Q000502:physiology*; D011085:Polycystic Ovary Syndrome / Q000175:diagnosis*; D011374:Progesterone / Q000097:blood
D006908:Hydroxyprogesterones; D011374:Progesterone; D019326:17-alpha-Hydroxyprogesterone; D000324:Adrenocorticotropic Hormone