Anti-inflammatory drugs in the treatment of allergic disease.
The treatment of asthma is undergoing significant change with an emphasis on anti-inflammatory therapy. While glucocorticoids are the most potent anti-inflammatory agent, certain patients fail to respond. These patients may be candidates for alternative anti-inflammatory therapy, such as troleandomycin, methotrexate, gold, hydroxychloroquine, or dapsone. In addition, the application of immunomodulator therapy, such as intravenous gamma globulin or cyclosporine, may be useful.
Szefler
S J
SJ
Department of Pediatrics, University of Colorado Health Sciences Center, Denver.
D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000145:classification / Q000627:therapeutic use; D001249:Asthma / Q000145:classification / Q000188:drug therapy* / Q000523:psychology; D001310:Auranofin / Q000008:administration & dosage / Q000627:therapeutic use; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use; D004205:Cromolyn Sodium / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005938:Glucocorticoids / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans; D006886:Hydroxychloroquine / Q000494:pharmacology / Q000627:therapeutic use; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D011788:Quality of Life; D012720:Severity of Illness Index; D013256:Steroids; D013806:Theophylline / Q000627:therapeutic use; D014217:Troleandomycin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use
D000318:Adrenergic beta-Agonists; D000893:Anti-Inflammatory Agents; D001993:Bronchodilator Agents; D005938:Glucocorticoids; D016756:Immunoglobulins, Intravenous; D013256:Steroids; D001310:Auranofin; D006886:Hydroxychloroquine; D013806:Theophylline; D014217:Troleandomycin; D004205:Cromolyn Sodium; D008727:Methotrexate