Molecular biological approaches to genetic disorders in prenatal diagnosis.
DNA analysis of Duchenne muscular dystrophy (DMD) and hemophilia A was performed with the aim of establishing the most efficient and reliable method for carrier and prenatal diagnosis in the Japanese population.
First Department of Obstetrics and Gynecology, School of Medicine, Toho University, Tokyo, Japan.
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Katayama
D015139:Blotting, Southern; D004247:DNA / Q000235:genetics*; D015342:DNA Probes; D005260:Female; D006580:Genetic Carrier Screening / Q000379:methods; D008040:Genetic Linkage; D006467:Hemophilia A / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D009136:Muscular Dystrophies / Q000175:diagnosis* / Q000235:genetics; D010375:Pedigree; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D015203:Reproducibility of Results; D014960:X Chromosome
D015342:DNA Probes; D004247:DNA