Intrahippocampal tetanus toxin produces generalized convulsions and neurodegeneration in rats: antagonism by NMDA receptor blockers.
Bowery
N G
NG
Department of Pharmacology, School of Pharmacy, London, UK.
Bagetta
G
G
Nisticó
G
G
Britton
P
P
Whitton
P
P
D015763:2-Amino-5-phosphonovalerate / Q000031:analogs & derivatives / Q000494:pharmacology; D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology*; D002220:Carbamazepine / Q000494:pharmacology; D003975:Diazepam / Q000494:pharmacology; D016291:Dizocilpine Maleate / Q000494:pharmacology; D004829:Epilepsy, Generalized / Q000139:chemically induced* / Q000473:pathology; D005971:Glutamates / Q000502:physiology; D018698:Glutamic Acid; D006624:Hippocampus / Q000187:drug effects* / Q000473:pathology; D008297:Male; D009410:Nerve Degeneration / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors / Q000187:drug effects* / Q000502:physiology; D013744:Tetanus Toxin / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D005680:gamma-Aminobutyric Acid / Q000502:physiology
D000927:Anticonvulsants; D005971:Glutamates; D016194:Receptors, N-Methyl-D-Aspartate; D013744:Tetanus Toxin; C064539:2-amino-4-methyl-5-phosphono-3-pentenoic acid; D002220:Carbamazepine; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D016291:Dizocilpine Maleate; D015763:2-Amino-5-phosphonovalerate; D003975:Diazepam