Formation of a carbamoyl glucuronide conjugate of carvedilol in vitro using dog and rat liver microsomes.
Schaefer
W H
WH
Department of Drug Metabolism, Smith Kline Beecham Pharmaceuticals, King of Prussia, PA 19406.
D000319:Adrenergic beta-Antagonists / Q000737:chemistry / Q000378:metabolism*; D000818:Animals; D002227:Carbazoles / Q000737:chemistry / Q000378:metabolism*; D000077261:Carvedilol; D002851:Chromatography, High Pressure Liquid; D004285:Dogs; D005965:Glucuronates / Q000737:chemistry / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism*; D011412:Propanolamines / Q000737:chemistry / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D000319:Adrenergic beta-Antagonists; D002227:Carbazoles; D005965:Glucuronates; D011412:Propanolamines; D000077261:Carvedilol