Factors affecting kidney transplantation success.
Forty percent of kidney transplants function for more than 10 years, allowing their recipients a lifestyle that is dialysis-free. Causes of success or failure of transplants are grouped into patient-related immunogenetic, pre- and perioperative, and postoperative factors. Some factors turn out to be interdependent, eg, the effect of pretransplantation transfusion and ethnic mismatch or donor age and ischemia; thus, no single analysis can be considered definitive. However, in documenting recent evidence gleaned predominantly from multifactorial analysis, we hope to assess relative risks associated with clinically important factors more accurately.
University of Bristol, Department of Transplantation Sciences, Medical School Unit, Southmead Centre for Medical Education, Southmead Health Services, Westbury-on Trym, UK.
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BA
Bradley
D000367:Age Factors; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology*; D012737:Sex Factors