[AFP producing gastric cancer manifested by metastasis to the tentorium cerebelli; case report and review of the literature].
We report a case of AFP producing gastric cancer manifested by metastasis to the tentorium cerebelli. A 66-year-old male patient was admitted with dysarthria, occipital headache and nausea on May 1, 1990. Neurological examination revealed signs of increased intracranial pressure and the right-sided cerebellar hemispheric signs. CT and MRI showed a round tumor shadow 3cm in diameter, which originated in the right-side tentorium cerebelli and grew in the posterior fossa. Tumor stains fed by the right tentorial artery were recognized by angiography. Serum AFP level was 503.5ng/ml. The patient underwent an operation under general anesthesia in the prone position. The tumor was totally removed via the suboccipital transtentorial approach. Histological examination revealed AFP producing adenocarcinoma. The patient was found to have a gastric cancer after neurosurgical operation, and underwent subtotal gastrectomy by surgeons. Serum AFP level was 254.5ng/ml after removal of metastatic brain tumor, and 5.0ng/ml after subtotal gastrectomy.
Department of Neurosurgery, Saiseikai-chuwa Hospital.
K
K
Goda
S
S
Tsunoda
T
T
Sakaki
T
T
Morimoto
H
H
Hashimoto
Y
Y
Yoshimura
N
N
Horikawa
H
H
Nakagawa
S
S
Iwasaki
D000230:Adenocarcinoma / Q000378:metabolism / Q000556:secondary* / Q000601:surgery; D000368:Aged; D002528:Cerebellar Neoplasms / Q000378:metabolism / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008297:Male; D013274:Stomach Neoplasms / Q000378:metabolism* / Q000473:pathology; D000509:alpha-Fetoproteins / Q000096:biosynthesis*
D000509:alpha-Fetoproteins