Animal models for the study of human immunodeficiency virus infections.
Recent studies in animal models have advanced our understanding of determinants of acquired immune deficiency syndrome pathogenesis. They have also indicated the potential importance of both the envelope glycoprotein of the virus that causes acquired immune deficiency syndrome and cell surface molecules in vaccine-elicited protective immunity.
Harvard Medical School, New England Regional Primate Research Center, Southborough, Massachusetts.
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D016915:AIDS Vaccines / Q000276:immunology; D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000517:prevention & control; D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D002415:Cats; D004195:Disease Models, Animal; D016181:Feline Acquired Immunodeficiency Syndrome / Q000276:immunology; D015483:HIV Antibodies / Q000276:immunology; D015658:HIV Infections / Q000276:immunology* / Q000517:prevention & control; D015497:HIV-1 / Q000276:immunology; D006801:Humans; D051379:Mice; D011323:Primates; D016511:Severe Combined Immunodeficiency / Q000276:immunology
D016915:AIDS Vaccines; D015483:HIV Antibodies