Alcohol consumption and risk-factors for ischemic heart disease in Chuckchi inhabitants: clinical, biological and population studies.
Clinical, biochemical and epidemiological research has shown variations of serum enzymatic constellations (relatively high level of GGT in Chuckchi natives compared to nonnative newcomers). This difference leads to different unspecific body resistance to exogenous factors, particularly to histamine-liberators. The GGT system has also been linked to alcohol-induced clinical IHD. Based on these findings patients will be screened for GGT activity, which may serve as a marker for population phenotypes representative of high-risk groups. This deficiency in GGT may indicate a high risk for alcohol-related heart disease.
N.I. Pirogov Second Medical Institute, Moscow.
T V
TV
Chernobrovkina
J V
JV
Arkavy
T I
TI
Astakhova
D000328:Adult; D000428:Alcohol Drinking; D004798:Enzymes / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000201:enzymology / Q000208:ethnology* / Q000209:etiology; D044468:Native Hawaiian or Pacific Islander; D044469:Racial Groups; D012307:Risk Factors; D012800:Siberia
D004798:Enzymes