[Pharmaceutical treatment of irritable bowel syndrome].
In the treatment of IBS best results could be obtained by implementing a comprehensive program for the patients. This might include a through examination, an explanation of the condition to the patients, psychologic managements, and correction of any bad habits, as well as drug therapy. The aim of drug therapy of IBS is the relief of the symptoms: such as abdominal pain, disturbed bowel function, anxiety or depression. As there is no drug which is effective in relieving the entire range of symptoms, drug should be chosen according to specific symptoms. Tranquilizers and antispasmodics may be the most commonly used drugs, however their efficacy is limited. To postprandial pain antispasmodics or trimebutine are most effective when prescribed before meal. Antidepressant are beneficial for the depressive state. Bulking agents are preferable mainly in relieving constipation, and loperamide is effective in treating diarrhea.
Inoue
M
M
Department of Health Care, School of Medicine, Fukuoka University.
D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003109:Colonic Diseases, Functional / Q000188:drug therapy* / Q000209:etiology; D004359:Drug Therapy, Combination; D005221:Fatigue / Q000150:complications; D006801:Humans; D010276:Parasympatholytics / Q000627:therapeutic use*; D013315:Stress, Psychological / Q000150:complications
D014151:Anti-Anxiety Agents; D000928:Antidepressive Agents; D010276:Parasympatholytics