Recurrent neuroleptic malignant syndrome in a man with mild mental handicap.
A case of recurrent neuroleptic malignant syndrome (NMS) occurring in a 29-year-old man with mild mental handicap and a superadded psychotic disorder is described. The case illustrates a number of unusual features such as recurrent episodes and resolution with administration of intravenous Procyclidine. The possibility of NMS occurring in people with mental handicap, who have a high level of neuroleptic drug prescription, must be borne in mind.
Bambrick
M
M
Department of Mental Handicap, University of Nottingham, England.
Wilson
D
D
D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002220:Carbamazepine / Q000008:administration & dosage / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D006220:Haloperidol / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy*; D008297:Male; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology*; D009460:Neurologic Examination; D009966:Orphenadrine / Q000008:administration & dosage / Q000009:adverse effects; D012008:Recurrence; D013469:Sulpiride / Q000008:administration & dosage / Q000009:adverse effects
D014150:Antipsychotic Agents; D002220:Carbamazepine; D013469:Sulpiride; D009966:Orphenadrine; D006220:Haloperidol