Alzheimer's disease: relationship of cognition and behavior to neurochemistry.
Alzheimer's disease is characterized by loss of cells and synapses in specific neural systems. The development of more effective therapies will depend on understanding the relationships between this pathology and the cognitive and behavioral impairments. In this review, focusing primarily on work in our laboratory, we will examine both classic and neuropeptide neurotransmitter systems and will discuss conceptual and methodological problems in relating clinical and biological measures.
Alzheimer Center, University Hospitals of Cleveland, Ohio.
P J
PJ
Whitehouse
D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology* / Q000523:psychology; D001921:Brain / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D011939:Mental Recall / Q000187:drug effects / Q000502:physiology; D009483:Neuropsychological Tests; D018377:Neurotransmitter Agents / Q000502:physiology
D018377:Neurotransmitter Agents