Application of reversibly soluble polymers in bioprocessing.
Reversibly soluble polyelectrolytes, whose solubility in aqueous solutions is dependent on factors such as pH or ionic strength, may be used as supports for enzymes or affinity ligands. Their dual nature may be exploited to take advantage of the soluble form during, for example, enzymatic reactions, and the insoluble form during downstream processing operations for enzyme or product recovery.
Niigata University, Faculty of Engineering, Japan.
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Fujii
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Taniguchi
D001709:Biotechnology / Q000379:methods*; D011232:Chemical Precipitation; D004573:Electrolytes / Q000737:chemistry*; D004798:Enzymes / Q000378:metabolism; D004800:Enzymes, Immobilized / Q000378:metabolism; D008024:Ligands; D011108:Polymers / Q000737:chemistry*; D012995:Solubility
D004573:Electrolytes; D004798:Enzymes; D004800:Enzymes, Immobilized; D008024:Ligands; D011108:Polymers