A rare FokI RFLP in the human dopamine D2 receptor gene (DRD2).
A new biallelic polymorphism for FokI restriction enzyme due to C----T transition in the fourth intron of human DRD2 is described. It must be a usefull marker of this candidate gene for several mental disorders.
INSERM U120, Hôpital Robert Debré, Paris, France.
C Y
CY
Lu
N
N
Gérard
A G
AG
Méreaux
A
A
Chaventré
J P
JP
Joly
J
J
Elion
R
R
Krishnamoorthy
D001483:Base Sequence; D002880:Chromosomes, Human, Pair 11 / Q000378:metabolism; D015252:Deoxyribonucleases, Type II Site-Specific / Q000378:metabolism; D005787:Gene Frequency / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D007438:Introns / Q000235:genetics; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics; D009838:Oligodeoxyribonucleotides / Q000235:genetics; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D011954:Receptors, Dopamine / Q000235:genetics*; D017448:Receptors, Dopamine D2; D044465:White People / Q000235:genetics
D005819:Genetic Markers; D009838:Oligodeoxyribonucleotides; D011954:Receptors, Dopamine; D017448:Receptors, Dopamine D2; C035042:endodeoxyribonuclease FokI; D015252:Deoxyribonucleases, Type II Site-Specific