Effect of phosphate on antibiotic and extracellular protein production by Myxococcus coralloides D.
The effect of inorganic phosphate concentrations on antibiotic and extracellular protein production by Myxococcus coralloides D have been examined. Antibiotic production by growing cells of this myxobacterium was maximal at phosphate concentrations of 10-20 mM, but was inhibited by concentrations higher than 20 mM. The total extracellular protein and the extracellular protein per cell ratio were independent of phosphate levels in the culture broth.
Gonzalez
F
F
Departamento de Microbiologia, Facultad de Ciencias, Universidad de Granada, Spain.
Montoya
M D
MD
Fárez
E
E
Arias
J M
JM
Montoya
E
E
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D001426:Bacterial Proteins / Q000096:biosynthesis*; D004305:Dose-Response Relationship, Drug; D005110:Extracellular Space / Q000032:analysis; D009231:Myxococcales / Q000187:drug effects* / Q000378:metabolism; D010710:Phosphates / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D010710:Phosphates