[Ergocalciferol Reference Standard (Control 901) of the National Institute of Hygienic Sciences].
Ergocalciferol Reference Standard for the Japanese Pharmacopoeia (JP RS) was prepared. The following analytical data were obtained: melting point 118.4 degrees C; UV and IR spectra were in agreement with both of the previous JP RS and USP RS of ergocalciferol; absorptivity at 265nm E1%lcm = 467; optical rotation [alpha]20D = 103 degrees; no impurities were detected by TLC and HPLC analyses; assay 100.1% by HPLC against the USP RS. Based on the above results, the raw material was authorized as the Reference Standard of the National Institute of Hygienic Sciences.
Kakehi
H
H
Komatsu
H
H
Murai
M
M
Ishimitsu
S
S
Okada
S
S
D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D004872:Ergocalciferols / Q000302:isolation & purification / Q000592:standards*; D006077:Government Agencies; D006920:Hygiene; D007564:Japan; D010602:Pharmacopoeias as Topic
D004872:Ergocalciferols