1H- and 13C-nmr assignments for taxol, 7-epi-taxol, and cephalomannine.
The 1H- and 13C-nmr spectra of taxol [1], 7-epi-taxol [2], and cephalomannine [3] were assigned using modern 1D and 2D nmr methods. Preliminary conformational information was obtained by nOe spectroscopy.
Chemical Synthesis and Analysis Laboratory, PRI/DYNCorp, Inc., National Cancer Institute-Frederick Cancer Research Facility, Maryland 21702-1201.
G N
GN
Chmurny
B D
BD
Hilton
S
S
Brobst
S A
SA
Look
K M
KM
Witherup
J A
JA
Beutler
D000470:Alkaloids / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D017239:Paclitaxel; D043823:Taxoids
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; C056348:cephalomannine; D017239:Paclitaxel