Thapsigargin, an inhibitor of Ca(2+)-ATPase, antagonizes vacuole formation of hepatoma cells induced by teleocidin.
First Department of Medicine, University of Tokyo, Japan.
A
A
Tsukamoto
Y
Y
Kaneko
K
K
Kurokawa
D000178:Acrylamides; D000818:Animals; D000252:Calcium-Transporting ATPases / Q000037:antagonists & inhibitors*; D003064:Cnidarian Venoms / Q000494:pharmacology; D004789:Enzyme Activation; D004988:Ethers, Cyclic / Q000494:pharmacology; D008114:Liver Neoplasms, Experimental / Q000473:pathology*; D008235:Lyngbya Toxins / Q000037:antagonists & inhibitors*; D019319:Okadaic Acid; D011493:Protein Kinase C / Q000378:metabolism; D013729:Terpenes / Q000494:pharmacology*; D019284:Thapsigargin; D014407:Tumor Cells, Cultured / Q000187:drug effects; D014617:Vacuoles / Q000187:drug effects*; D000095702:Polyether Toxins
D000178:Acrylamides; D000252:Calcium-Transporting ATPases; D003064:Cnidarian Venoms; D004988:Ethers, Cyclic; D008235:Lyngbya Toxins; D019319:Okadaic Acid; D011493:Protein Kinase C; D013729:Terpenes; D019284:Thapsigargin; C022176:teleocidins; C010272:palytoxin; D000095702:Polyether Toxins