Effects of salt acclimation on water and urea permeabilities across the frog bladder: relationship with intramembrane particle aggregates.
1. In salt-acclimated frogs, water and urea bladder permeabilities are markedly higher than in tap water-acclimated animals. 2. Intra-membrane particle aggregates (IMPA) cover an unusually large surface area of the salt-acclimated frog bladder apical plasma membrane. 3. In saline-adapted animals, proteins extracted from the apical plasma membrane contain additional species of 19, 26, 31 and 53-61 kDa. These proteins might be related to the water channels contained by IMPA.
Service de Biologie Cellulaire, Centre d'Etudes Nucléaires de Saclay, Gif-sur-Yvette, France.
J M
JM
Verbavatz
A
A
Frigeri
R
R
Gobin
P
P
Ripoche
J
J
Bourguet
D000222:Adaptation, Physiological / Q000187:drug effects*; D000818:Animals; D002462:Cell Membrane / Q000502:physiology / Q000648:ultrastructure; D004058:Diffusion; D015180:Electrophoresis, Gel, Two-Dimensional; D004848:Epithelium / Q000378:metabolism / Q000502:physiology; D005260:Female; D005614:Freeze Fracturing; D008854:Microscopy, Electron; D010539:Permeability; D011893:Rana esculenta; D012965:Sodium Chloride / Q000494:pharmacology*; D014508:Urea / Q000493:pharmacokinetics*; D001743:Urinary Bladder / Q000378:metabolism / Q000502:physiology* / Q000648:ultrastructure; D014867:Water / Q000378:metabolism*
D014867:Water; D012965:Sodium Chloride; D014508:Urea