Fatty liver induced by the addition of excess cystine to a soy-bean protein diet in rats.
1. The effects of excess cystine added to diets with casein, egg protein, soya-bean protein and wheat gluten as protein source on liver and serum lipids of rats were compared. 2. The addition of excess cystine to a soya-bean protein diet produced lipid accumulation in the liver. 3. The addition of excess cystine to casein, egg protein and soya-bean protein diets, but not a wheat gluten diet, increased serum cholesterol.
Department of Agricultural Chemistry, School of Agriculture, Nagoya University, Japan.
Y
Y
Aoyama
H
H
Matsumoto
E
E
Hitomi-Ohmura
A
A
Yoshida
D000818:Animals; D002364:Caseins / Q000008:administration & dosage; D003553:Cystine / Q000008:administration & dosage*; D004044:Dietary Proteins / Q000008:administration & dosage / Q000633:toxicity*; D005234:Fatty Liver / Q000209:etiology* / Q000378:metabolism; D005983:Glutens / Q000008:administration & dosage; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood; D008099:Liver / Q000378:metabolism; D008297:Male; D010047:Ovalbumin / Q000008:administration & dosage; D014674:Plant Proteins, Dietary / Q000008:administration & dosage / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains; D030262:Soybean Proteins
D002364:Caseins; D004044:Dietary Proteins; D008055:Lipids; D014674:Plant Proteins, Dietary; D030262:Soybean Proteins; D003553:Cystine; D005983:Glutens; D010047:Ovalbumin