Some personal views on the control of schistosomiasis mansoni.
Our views are based, among other, on a recent study of a district of União dos Palmares (Alagoas). Although being a very compact community (32 city blocks holding two thousand families), transmission is very uneven, the geometric mean egg counts in the various blocks ranging between extremes of 96 and 1920. (Results do not correlate with the availability of domestic water supply). We thus are led to conclude that: (a) transmission is primarily peridomestic, resulting from pollution of open ditches and other collections of water; (b) control of transmission can be done on a selective basis, requiring quite modest investments. Given the inefficacy of population-based chemotherapy, when used alone, the author insists that this alternative cannot any longer be overlooked. He also regrets the emphasis placed upon vaccine development; allegations that this would, at any rate, prevent severe morbidity can be dismissed, since-whatever the cause-morbidity due to schistosomiasis has been rapidly declining in Northeast Brazil.
Departamento de Medicina Social, Escola de Medicina, Universidade Federal de Pelotas, Brasil.
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Kloetzel
D000293:Adolescent; D000818:Animals; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D006801:Humans; D010270:Parasite Egg Count; D012499:Sanitation / Q000191:economics; D012555:Schistosomiasis mansoni / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D012556:Schistosomicides / Q000627:therapeutic use; D012959:Socioeconomic Factors; D014505:Urban Population; D014611:Vaccination; D014876:Water Pollution / Q000191:economics / Q000517:prevention & control*; D014881:Water Supply
D012556:Schistosomicides