Impact of the long term supply of iodized salt to the endemic goitre area.
The study was designed to assess the impact of the supplementation levels of iodine in salt supplied since the last 12 years to Gilgit and Hunza, an endemic goitre area of Pakistan. The overall prevalence of visible goitre is reduced from 61.36% to 4.68%. Results of urinary excretion of iodine (UEI) indicate severe to mild iodine deficiency among 70.41% of the randomly surveyed households. Severely deficient are 3%, moderate 29.54% and mild 37.87%, criteria of UEI being less than 2.0 micrograms/dl, 2-5 micrograms/dl and 5-10 micrograms/dl respectively. Levels of iodine supplementation in 267 iodized salt samples at production (n = 128) and consumption (n = 139) points are compared with a mean +/- SD are 70.86 +/- 29.73 ppm and 37.24 +/- 20.47 ppm respectively, representing 566.8 +/- 237.8 micrograms and 297.9 +/- 163.7 micrograms of iodine per 8.0 gram of salt. It is suggested to replace common salt with iodized salt in the goitre area to ensure the use by all households and quality control measures for iodination of salt should strictly be adhered so that uniform and consistent supply of iodine be ensured. The magnitude of contributory factors other than iodine deficiency, i.e., environmental and hereditary should be monitored and considered when levels of iodine supplementation are adjusted.
Ali
A
A
National Institute of Health NIH, Islamabad.
Khan
M M
MM
Malik
Z U
ZU
Charania
B A
BA
Bhojani
F A
FA
Baig
S M
SM
D005260:Female; D006043:Goiter, Endemic / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007455:Iodine / Q000008:administration & dosage* / Q000172:deficiency / Q000652:urine; D008297:Male; D010154:Pakistan / Q000453:epidemiology; D015995:Prevalence; D012965:Sodium Chloride / Q000032:analysis / Q000600:supply & distribution; D017673:Sodium Chloride, Dietary / Q000008:administration & dosage*; D013997:Time Factors
D017673:Sodium Chloride, Dietary; C034024:iodized salt; D012965:Sodium Chloride; D007455:Iodine