Neuropharmacology of pain.
Recent research on the site of action of morphine, its distribution following systemic administration and activity in a model of neuropathic pain is reviewed. Neuropeptides and pain is discussed in relation to tachykinins and their antagonists, cholecystokinin (CCK) and its antagonists and somatostatin.
Department of Preclinical Veterinary Sciences, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Scotland, UK.
A W
AW
Duggan
D000818:Animals; D002766:Cholecystokinin / Q000502:physiology; D004723:Endorphins / Q000502:physiology*; D006801:Humans; D009437:Neuralgia / Q000503:physiopathology; D009619:Nociceptors / Q000503:physiopathology*; D010146:Pain / Q000503:physiopathology*; D011942:Receptors, Adrenergic, alpha / Q000502:physiology; D011957:Receptors, Opioid / Q000502:physiology*; D012684:Sensory Thresholds / Q000502:physiology; D013004:Somatostatin / Q000502:physiology; D015320:Tachykinins / Q000502:physiology
D004723:Endorphins; D011942:Receptors, Adrenergic, alpha; D011957:Receptors, Opioid; D015320:Tachykinins; D013004:Somatostatin; D002766:Cholecystokinin