A farnesyl arabinoside as an enhancer of glucose transport in rat adipocytes from a soft coral, Sinularia sp.
Separation of a lipophilic extract of a soft coral, Sinularia sp., assayed by enhancement of glucose transport in rat adipocytes, gave farnesyl 4-O-beta-D-arabinopyranosyl-beta-D-arabinopyranoside-2,2',3- triacetate (1a) whose structure was determined by spectroscopy. Enhancers of glucose transport may be useful for the prevention and treatment of diabetic disorders.
Shindo
T
T
New Lead Research Laboratories, Sankyo Co. Ltd., Tokyo, Japan.
Sato
A
A
Horikoshi
H
H
Kuwano
H
H
D000273:Adipose Tissue / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D003063:Cnidaria / Q000737:chemistry*; D005204:Farnesol / Q000494:pharmacology*; D005947:Glucose / Q000378:metabolism*; D051381:Rats; D012503:Saponins / Q000494:pharmacology*; D013729:Terpenes
D012503:Saponins; D013729:Terpenes; C075933:farnesyl 4-O-arabinopyranosyl-arabinopyranoside-2,2',3-triacetate; D005204:Farnesol; D005947:Glucose