[Evidence that excessive sedimentation rate is predictive of traffic accidents in systemic diseases].
OBJECTIVE
To identify the factors accelerating the sedimentation rate and to determine whether an excessive quickness may be responsible of the circulatory accident in systemic diseases.


METHODS
The sedimentation rate has been enregistred in 100 patients with systemic diseases known for having a major quickness. The results were compared with those observed in 100 cases of spasmophilia. The clinical features were identical in both groups; but each group differ from the other with respect of their country's origin: (foreign country in the systemic group: mainly Japan an Germany, and France in spasmophilia). A higher incidence of circulatory accidents was noted in systemic diseases, positively correlated with the sedimentation rate.


CONCLUSIONS
The main cause of circulatory accidents in systemic diseases is an excess of sedimentation quickness which especially concern systemic diseases of foreign origin. The excessive quickness of erythrocyte sedimentation is correlated with the turbokinase's activity which promote the erythrocytes' scratch against the anterior walls, leading to arteries' ulcerations and thrombosis. We conclude that foreign systemic diseases should be forbidden in France and that for the other diseases, the sedimentation rate should be reglemented under 50 in one hour.
Dupond
J L
JL
Service de Médecine Interne et Immunologie Clinique, CHU Jean Minjoz, Besançon.
D000063:Accidents, Traffic; D001799:Blood Sedimentation; D004194:Disease; D006801:Humans; D014925:Wit and Humor as Topic
Responsabilité d'une vitesse de sédimentation excessive dans les accidents de la circulation au cours des maladies systémiques.