[The significance of the content of connective tissue metabolites in the blood serum for the diagnosis of chronic viral hepatitis and liver cirrhosis].
With the purpose of improving early clinico-biochemical diagnosis of viral chronic active hepatitis and liver cirrhosis in children, the authors used indices of connective tissue metabolism--determination of free oxiprolin and neutral lipids in the blood serum. High levels of free oxiprolin and neutral lipids were revealed in patients with chronic active hepatitis and low--in liver cirrhosis. These data characterize different reactions of the connective tissue in the named diseases determined by different morphological maturity grades and secretory activity of fibroblasts.
Smirnov
B M
BM
Trishkova
L A
LA
D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003238:Connective Tissue / Q000378:metabolism*; D005260:Female; D006509:Hepatitis B / Q000097:blood / Q000175:diagnosis*; D006521:Hepatitis, Chronic / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D006909:Hydroxyproline / Q000097:blood; D008055:Lipids / Q000097:blood; D008103:Liver Cirrhosis / Q000097:blood / Q000175:diagnosis*; D008297:Male
D015415:Biomarkers; D008055:Lipids; D006909:Hydroxyproline
Znachenie soderzhaniia metabolitov soedinitel'noĭ tkani v syvorotke krovi dlia diagnostiki virusnogo khronicheskogo gepatita i tsirroza pecheni.