Secondary Hodgkin's disease in polymyositis and type 1 diabetes mellitus after a long-term immunosuppressive treatment.
Immunological disorders can play an important role in the etiopathogenesis of malignant lymphogranuloma. The authors demonstrate a patient with autoimmune polymorbidity (polymyositis and type 1 diabetes mellitus) which underwent a long-term immunosuppressive and cytostatic therapy. After 7 years of that treatment, Hodgkin's disease of mixed cellularity type developed. The clinical findings of the case are described and the clinical particularities along with possible mutual links among these diseases are stressed.
IInd Department of Medicine, University Hospital, Olomouc, Czechoslovakia.
J
J
Pumprla
D
D
Galuszková
J
J
Dusková
I
I
Krc
D003882:Dermatomyositis / Q000150:complications / Q000188:drug therapy*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006689:Hodgkin Disease / Q000139:chemically induced / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D017285:Polymyositis / Q000150:complications / Q000188:drug therapy*
D007166:Immunosuppressive Agents; D007328:Insulin