Live attenuated vaccines for human use.
Live attenuated vaccines have been successfully used for the prevention of a number of viral and bacterial diseases. Several vaccine strains have been utilized recently as expression vectors for cloned heterologous antigens. Through the use of recombinant DNA technology, candidate vaccine strains and vector systems have been developed and are undergoing clinical evaluation.
Cryz
S J
SJ
Swiss Serum and Vaccine Institute, Berne.
D001709:Biotechnology; D004274:DNA, Recombinant; D006801:Humans; D012449:Safety; D014613:Vaccines, Attenuated; D014614:Vaccines, Synthetic
D004274:DNA, Recombinant; D014613:Vaccines, Attenuated; D014614:Vaccines, Synthetic