Oncogene RNA expression in three human lymphoblastic leukemia cell lines lymphocytes.
We have explored the RNA oncogene expression by three human acute lymphoblastic leukemia lines, NALM-6, MOLT-3, and REH. We compared such expression with that of normal human lymphocytes. Marked differences in the RNA expression of the third exon of c-myc, v-myb, v-Hras, N-ras, v-fes, and v-fos were found. We noted minimal or no differences in the RNA expression of v-abl, B-lym, v-erb-B, c-ets, v-fms, v-kras, v-mos, v-raf, and v-sis.
Pediatric Hematology/Oncology Division, James Whitcomb Riley Hospital for Children, Indianapolis, Indiana 46202-5225.
J
J
Goldman
W A
WA
McGuire
D002460:Cell Line; D006801:Humans; D008214:Lymphocytes / Q000737:chemistry; D009857:Oncogenes; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics*; D012313:RNA / Q000032:analysis*; D014407:Tumor Cells, Cultured
D012313:RNA