[Migration inhibition test with thyroid membrane antigen in Graves-Basedow disease and nodular goiter].
The evaluation of the migration inhibition test with thyroid membrane antigen was carried out in 20 patients with Graves' disease, 13 patients with neutral nodular goiter and 13 healthy subjects. A significant inhibition of migration by thyroid antigen as compared to the control group was demonstrated only in the patients with Graves' disease (the value of the migration index was 0.57 +/- 0.07). The respective value was 0.79 +/- 0.16 in patients with nodular goiter and 0.85 +/- 0.11 in healthy subjects. The results obtained indicate the practical value of the migration inhibition test in diagnosing the thyroid diseases having an autoimmune background.
Katedra i Klinika Chorób Wewnetrznych i Alergologii Slăskiej AM w Zabrzu.
J
J
Jarzab
E
E
Bachowska
B
B
Jarzab
J
J
Skrzypek
J
J
Waler
D000328:Adult; D000954:Antigens, Surface / Q000032:analysis*; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000276:immunology*; D002464:Cell Migration Inhibition; D005260:Female; D006044:Goiter, Nodular / Q000175:diagnosis / Q000276:immunology*; D006111:Graves Disease / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D008297:Male; D008562:Membrane Glycoproteins / Q000276:immunology; D008875:Middle Aged; D013961:Thyroid Gland / Q000276:immunology*
D000954:Antigens, Surface; D008562:Membrane Glycoproteins
Odczyn hamowania migracji z błonowym antygenem tarczycowym w chorbie Graves-Basedowa i w wolu guzkowym.