[Beta-blockers in the prevention of the rupture of esophageal varices. A meta-analysis].
The meta-analysis of 5 trials for primary prevention and of 18 trials of secondary prevention emphasizes the effect of beta-blockers in the decrease of variceal bleedings in cirrhosis. Beta-blockers are reducing the bleeding events with 32% in the primary prevention and with 28% in the secondary prevention. The mortality is reduced by 15%, respectively by 23%. This is the first meta-analysis reported in the Romanian gastroenterological literature.
Clinica Medicală III, Ciuj.
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Dumitraşcu
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D004932:Esophageal and Gastric Varices / Q000150:complications / Q000188:drug therapy* / Q000401:mortality; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000401:mortality / Q000517:prevention & control*; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D012422:Rupture, Spontaneous
D000319:Adrenergic beta-Antagonists
Beta-blocantele în profilaxia rupturii varicelor esofagiene. O meta-analiză.