Cranial nerve involvement in childhood polyarteritis nodosa.
Amongst a variety of neurological manifestations of childhood polyarteritis nodosa, cranial nerve involvement is unusual. We report 4 cases with cranial nerve palsies in a series of 36 biopsy-proven patients. Two cases presented with IIIrd nerve palsy alone, one with right IIIrd and left IVth nerve palsy, and one with peripheral VIIth nerve paresis. All 4 patients showed good response to prednisolone and cyclophosphamide treatment. Cranial nerve involvement in childhood polyarteritis nodosa seems not so rare when patients are followed on long term basis.
Topaloglu
R
R
Department of Pediatric Nephrology, Hacettepe University Children's Hospital, Ankara, Turkey.
Besbas
N
N
Saatci
U
U
Bakkaloglu
A
A
Oner
A
A
D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003389:Cranial Nerve Diseases / Q000188:drug therapy / Q000235:genetics / Q000473:pathology*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000473:pathology; D009132:Muscles / Q000098:blood supply; D009460:Neurologic Examination / Q000187:drug effects; D010488:Polyarteritis Nodosa / Q000188:drug therapy / Q000235:genetics / Q000473:pathology*; D011239:Prednisolone / Q000008:administration & dosage; D012867:Skin / Q000098:blood supply
D003520:Cyclophosphamide; D011239:Prednisolone