[Pulmonary edema in patients with hemorrhagic fever with renal syndrome].
Eight patients suffering from hemorrhagic fever with renal syndrome (HFRS) running a severe course complicated by pulmonary edema developed absolute hyperhistaminemia and hyperserotoninemia, histamine and serotonin accumulation in tissues. These amines inactivation in blood and lungs and excretion of catecholamines with urine got disturbed. High blood and lung tissue levels of biologically active substances resultant in enhanced permeability of the vascular wall and alveolar epithelium, hemodynamic disturbances due to hypoexcretory hypercatecholaminemia are thought to underlie the occurrence of this grave HFRS complication.
Sidel'nikov
Iu N
IuN
Koval'skiĭ
G S
GS
Sivoraksha
G A
GA
D000328:Adult; D005260:Female; D006480:Hemorrhagic Fever with Renal Syndrome / Q000097:blood / Q000150:complications* / Q000628:therapy; D006632:Histamine / Q000097:blood / Q000378:metabolism; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011654:Pulmonary Edema / Q000188:drug therapy / Q000209:etiology*; D006435:Renal Dialysis; D012701:Serotonin / Q000097:blood / Q000378:metabolism; D012702:Serotonin Antagonists / Q000627:therapeutic use; D013997:Time Factors; D014462:Ultrafiltration
D006633:Histamine Antagonists; D012702:Serotonin Antagonists; D012701:Serotonin; D006632:Histamine
Otek legkih u bol'nykh gemorragicheskoĭ likhoradkoĭ s pochechnym sindromom.