Effect of phosphate on antibiotic and extracellular protein production by Myxococcus coralloides D.
The effect of inorganic phosphate concentrations on antibiotic and extracellular protein production by Myxococcus coralloides D have been examined. Antibiotic production by growing cells of this myxobacterium was maximal at phosphate concentrations of 10-20 mM, but was inhibited by concentrations higher than 20 mM. The total extracellular protein and the extracellular protein per cell ratio were independent of phosphate levels in the culture broth.
Departamento de Microbiologia, Facultad de Ciencias, Universidad de Granada, Spain.
F
F
Gonzalez
M D
MD
Montoya
E
E
Fárez
J M
JM
Arias
E
E
Montoya
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D001426:Bacterial Proteins / Q000096:biosynthesis*; D004305:Dose-Response Relationship, Drug; D005110:Extracellular Space / Q000032:analysis; D009231:Myxococcales / Q000187:drug effects* / Q000378:metabolism; D010710:Phosphates / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D010710:Phosphates