[Changes in plasma lipoproteins in Mediterranean boutonneuse fever].
We report 25 cases of boutonneuse fever with, in the acute phase, an increase of plasma transaminases, triglycerides and apoprotein B levels, a decrease of total, HDL and LDL cholesterol and a decrease of apoprotein A. These changes disappeared 1 to 4 weeks after the beginning of treatment. They might be due to a reduced activity of lecithin-cholesterol acetyltransferase and lipoprotein lipase, probably caused by the hepatic and vascular disorders frequently found in this disease.
Service de Médecine interne, HG Virgen de las Nieves, Granada, Espagne.
A
A
el Amrani Marini
P
P
Aranegui Lasuen
J M
JM
Barcelo Valcarcel
P
P
Giner Escobar
A
A
Corrales Torres
J
J
Jimenez Alonso
D000328:Adult; D000368:Aged; D001054:Apolipoproteins A / Q000032:analysis; D001055:Apolipoproteins B / Q000097:blood; D001907:Boutonneuse Fever / Q000097:blood* / Q000201:enzymology; D005260:Female; D006801:Humans; D008071:Lipoprotein Lipase / Q000378:metabolism; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D007862:Phosphatidylcholine-Sterol O-Acyltransferase / Q000378:metabolism; D000637:Transaminases / Q000097:blood; D014280:Triglycerides / Q000097:blood; D005723:gamma-Glutamyltransferase / Q000097:blood
D001054:Apolipoproteins A; D001055:Apolipoproteins B; D008074:Lipoproteins; D014280:Triglycerides; D007862:Phosphatidylcholine-Sterol O-Acyltransferase; D005723:gamma-Glutamyltransferase; D000637:Transaminases; D008071:Lipoprotein Lipase
Modifications des lipoprotéines plasmatiques au cours de la fièvre boutonneuse méditerranéenne.