Automatic bioprocess control. 2. Implementations and practical experiences.
Our improved implementation for bioprocess control allows flexible responses to many process needs. It is based on computer equipment consisting of three hierarchically ordered levels. On the lowest level, a DDC slave computer handles setpoints and simple tasks generating the chemical and physical environment for the cells. It can be designed manually by the user or automatically by the supervisory computer on the second level. This provides for raw data organization, analysis and interpretation either to support personnel on line in decision making, to select predefined control strategies, or even to search for others. In the coordinating computer on the third level, common tasks of different supervisory computers (bioprocesses) are shared, saving money for the equipment. Tasks and concepts as well as experimental experiences are described to outline the capabilities of the configuration.
Institute of Biotechnology, ETH Hönggerberg, Zurich, Switzerland.
G
G
Locher
B
B
Sonnleitner
A
A
Fiechter
D001709:Biotechnology; D003199:Computer Systems; D012984:Software