Insect peptide hormones, an overview of the present literature.
A comprehensive overview of the recent state of the art of insect peptide hormones with chemical structures is presented. An increased interest in insect neuropeptides and dynamic development of that research area has been influenced by a rapid improvement of instrumentation necessary for isolation and structural characterization. Several research teams have studied the relationships between biological properties of insect and vertebrate peptide hormones. Thus hormones from the AKH family can be considered glucagon counterparts, whereas the myotropic hormones such as proctolin and Lem-PK (LPK) are a substance P equivalent. Insect melanization hormones Bom-MRCH in their structural characteristics and properties resemble those of mammal MSH, and leucosulfakinins Lem-SK-I and -II show some similarities with gastrin II and cholecystokinin. Bombyxin-II (Bom-PTTH-II) reveals a structural homology with human insulin and similar biological properties to adenocorticotropic mammal hormone. Allatostatin (Dip-JHS-I) may be compared to somatostatin as it can be inferred from the observations that this peptide modulates JH secretion in cockroach, Blattella germanica. Determination of the primary structure of eclosion hormones Mas-EH and Bom-EH-II as well as the amino acid sequence of allatotropin and allatostatin is a significant contribution to the understanding of the molecular mechanisms of metamorphosis and insect development.
Institute of Chemistry, University of Wrocław, Poland.
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Rosiński
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Sobótka
D000595:Amino Acid Sequence; D000818:Animals; D007301:Insect Hormones / Q000737:chemistry* / Q000302:isolation & purification / Q000502:physiology; D007313:Insecta / Q000737:chemistry* / Q000502:physiology; D008969:Molecular Sequence Data; D009479:Neuropeptides / Q000737:chemistry / Q000302:isolation & purification / Q000502:physiology; D018377:Neurotransmitter Agents / Q000737:chemistry / Q000302:isolation & purification / Q000502:physiology; D009842:Oligopeptides / Q000737:chemistry* / Q000302:isolation & purification / Q000502:physiology; D014280:Triglycerides / Q000378:metabolism
D007301:Insect Hormones; D009479:Neuropeptides; D018377:Neurotransmitter Agents; D009842:Oligopeptides; D014280:Triglycerides