Changes in specificities of human monoclonal antibodies by introduction of drug-resistance gene into hybridomas.
Shirahata
S
S
Graduate School of Genetic Resources Technology, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
Tachibana
H
H
Mori
T
T
Seki
K
K
Yamada
K
K
Murakami
H
H
D000230:Adenocarcinoma / Q000276:immunology; D000911:Antibodies, Monoclonal / Q000096:biosynthesis* / Q000235:genetics / Q000378:metabolism; D000918:Antibody Specificity; D000951:Antigens, Neoplasm / Q000276:immunology; D001665:Binding Sites; D002460:Cell Line; D004273:DNA, Neoplasm / Q000276:immunology / Q000378:metabolism; D004351:Drug Resistance / Q000235:genetics*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D006825:Hybridomas / Q000276:immunology / Q000502:physiology*; D007075:Immunoglobulin M / Q000096:biosynthesis / Q000235:genetics / Q000276:immunology; D008175:Lung Neoplasms / Q000276:immunology
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D004273:DNA, Neoplasm; D007075:Immunoglobulin M