Anti-inflammatory drugs in the treatment of allergic disease.
The treatment of asthma is undergoing significant change with an emphasis on anti-inflammatory therapy. While glucocorticoids are the most potent anti-inflammatory agent, certain patients fail to respond. These patients may be candidates for alternative anti-inflammatory therapy, such as troleandomycin, methotrexate, gold, hydroxychloroquine, or dapsone. In addition, the application of immunomodulator therapy, such as intravenous gamma globulin or cyclosporine, may be useful.
Department of Pediatrics, University of Colorado Health Sciences Center, Denver.
S J
SJ
Szefler
D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000145:classification / Q000627:therapeutic use; D001249:Asthma / Q000145:classification / Q000188:drug therapy* / Q000523:psychology; D001310:Auranofin / Q000008:administration & dosage / Q000627:therapeutic use; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use; D004205:Cromolyn Sodium / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005938:Glucocorticoids / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans; D006886:Hydroxychloroquine / Q000494:pharmacology / Q000627:therapeutic use; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D011788:Quality of Life; D012720:Severity of Illness Index; D013256:Steroids; D013806:Theophylline / Q000627:therapeutic use; D014217:Troleandomycin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use
D000318:Adrenergic beta-Agonists; D000893:Anti-Inflammatory Agents; D001993:Bronchodilator Agents; D005938:Glucocorticoids; D016756:Immunoglobulins, Intravenous; D013256:Steroids; D001310:Auranofin; D006886:Hydroxychloroquine; D013806:Theophylline; D014217:Troleandomycin; D004205:Cromolyn Sodium; D008727:Methotrexate