Characterization of field isolates of suid herpesvirus 1 (Aujeszky's disease virus) as derivatives of attenuated vaccine strains.
Field isolates of suid herpesvirus 1 (Aujeszky's disease virus) from Poland and Hungary were identified by restriction fragment pattern analysis as derivatives of attenuated vaccine strains. The Polish isolates were found to be related to the BUK-TK-900 strain (Suivac A) which is widely used as a live vaccine in Poland, and the Hungarian isolates were related to the Bartha K-61 vaccine strain widely used in Hungary. Pigs experimentally infected with derivatives of BUK-TK-900 or BUK-TK-900 itself were found to develop gI-antibodies, while pigs infected with derivatives of Bartha K-61 showed a gI-negative response.
State Veterinary Institute for Virus Research, Kalvehave, Denmark.
L S
LS
Christensen
I
I
Medveczky
B S
BS
Strandbygaard
Z
Z
Pejsak
D000818:Animals; D015139:Blotting, Southern; D002478:Cells, Cultured; D005589:Foxes / Q000382:microbiology; D011558:Herpesvirus 1, Suid / Q000302:isolation & purification / Q000502:physiology*; D006814:Hungary; D011044:Poland; D012150:Polymorphism, Restriction Fragment Length; D011557:Pseudorabies / Q000382:microbiology*; D013552:Swine / Q000382:microbiology; D014613:Vaccines, Attenuated / Q000302:isolation & purification; D014765:Viral Vaccines / Q000302:isolation & purification*
D014613:Vaccines, Attenuated; D014765:Viral Vaccines