[The importance of S-100 protein positive Langerhans cells and Leu-M1 positive tumor cells for prognosis of papillary thyroid cancer].
In a period of 10 years (1981-90) papillary thyroid carcinomas were found in 124 cases. In 95 cases we were able to perform immunohistochemical studies for Leu-M1 antigen and S-100 protein. The examination of these cases has revealed that the presence of S-100 positive Langerhans cells yields no additional information for the prognosis of the papillary thyroid carcinoma. But we observed that the existence of Leu-M1 positive tumour cells is connected with a poor postoperative course of disease in comparison to Leu-M1 negative tumours.
Institut für Pathologie, Medizinischen Akademie Magdeburg.
C
C
Willgeroth
R
R
Floegel
B
B
Rösler
D015703:Antigens, CD / Q000032:analysis*; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000032:analysis*; D002291:Carcinoma, Papillary / Q000276:immunology / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007801:Langerhans Cells / Q000276:immunology / Q000473:pathology*; D016256:Lewis X Antigen; D008297:Male; D011379:Prognosis; D009418:S100 Proteins / Q000032:analysis*; D015996:Survival Rate; D013961:Thyroid Gland / Q000276:immunology / Q000473:pathology; D013964:Thyroid Neoplasms / Q000276:immunology / Q000401:mortality / Q000473:pathology* / Q000601:surgery
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D014408:Biomarkers, Tumor; D016256:Lewis X Antigen; D009418:S100 Proteins
Die Bedeutung von S-100 Protein-positiven Langerhanszellen und Leu-M1-positiven Tumorzellen für die Prognose papillärer Schildrüsenkarzinome.