[The effect of narcotic analgesics on nociceptive reactions of a visceral and somatic nature].
The experiments on conscious cats showed that buprenorphine given in 0.0125 and 0.025 mg/kg selectively inhibited motor, emotional and hemodynamic manifestations of pain induced by stimulation of the splanchnic nerve. The analgetic effect of morphine, tramal, pentazocine and butorphanol was equally demonstrated on visceral and somatic pain models, but the drugs elevated the baseline blood pressure and produced no (morphine, pentazocine) or moderate (tramal, butorphanol) antihypertensive effects in various nociceptive stimuli.
A A
AA
Zaĭtsev
Iu D
IuD
Ignatov
A O
AO
Khar'kovskiĭ
D000701:Analgesics, Opioid / Q000494:pharmacology*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D009619:Nociceptors / Q000187:drug effects* / Q000502:physiology; D010146:Pain / Q000503:physiopathology; D013153:Splanchnic Nerves / Q000502:physiology
D000701:Analgesics, Opioid
Vliianie narkoticheskikh anal'getikov na notsitseptivnye reaktsii vistseral'noĭ i somaticheskoĭ prirody.