Antibody expression in bacteriophage systems: the future of monoclonal antibodies?
Bacteriophage systems have been utilized to express and isolate antibodies. This promising technology has been evolving rapidly and has the potential to revolutionize the way in which monoclonal antibodies are generated. This review focuses on the many recent advances that have been made in obtaining monoclonal antibodies from bacteriophage systems.
Garrard
L J
LJ
Genentech Inc, South San Francisco.
Zhukovsky
E A
EA
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis / Q000235:genetics*; D010582:Bacteriophage lambda / Q000235:genetics; D001435:Bacteriophages / Q000235:genetics*; D001709:Biotechnology; D003001:Cloning, Molecular; D015870:Gene Expression; D015723:Gene Library; D006801:Humans
D000911:Antibodies, Monoclonal