Approaches to HIV vaccine design.
Contemporary vaccines are relying increasingly on modern biotechnology and a vaccine against the AIDS virus is expected to depend even more on new technological advances. Four basic areas of vaccine development are discussed in this context: (1) selection and preparation of candidate immunogens; (2) presentation of immunogens to the immune system; (3) pre-clinical testing of vaccine candidates; and (4) monitoring of vaccine clinical trials.
Duke University Medical Center, Durham, NC 27710.
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Bolognesi
D000163:Acquired Immunodeficiency Syndrome / Q000517:prevention & control*; D000818:Animals; D000956:Antigens, Viral / Q000235:genetics / Q000276:immunology; D001709:Biotechnology; D002986:Clinical Trials as Topic; D004195:Disease Models, Animal; D015195:Drug Design; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D014765:Viral Vaccines / Q000276:immunology*
D000956:Antigens, Viral; D014765:Viral Vaccines