Reductive biotransformation of xenobiotics by the sheep ruminal content.
1. Sheep ruminal content was able to reduce nitro groups from nitrobenzene and azo groups from dimethylamino-azobenzene. 2. Results might be of interest in relation to ruminants exposed to environmental chemicals via oral route. 3. Biotransformation of xenobiotics in rumen might give to deleterious products appearing later in meat and/or milk or harming the ruminant itself.
Acosta de Pérez
O
O
Centro de Diagnóstico e Investigaciones Veterinarias Formosa CEDIVEF.
Bernacchi
A S
AS
Díaz de Toranzo
E G
EG
Castro
J A
JA
D000818:Animals; D001711:Biotransformation; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism; D009601:Nitroreductases / Q000378:metabolism; D012417:Rumen / Q000201:enzymology / Q000378:metabolism*; D012756:Sheep / Q000378:metabolism*; D015262:Xenobiotics / Q000493:pharmacokinetics*
D015262:Xenobiotics; D009247:NADH, NADPH Oxidoreductases; D009601:Nitroreductases; C021106:azoreductase