[Behavior of granulocytic receptors for Fc IgG fragment and C3 component of complement in patients with diabetes].
The count of peripheral neutrophils having the superficial receptors for Fc IgG fragment (FcR) and C3 component of the complement (CR) was determined in diabetic patients by using the rosette tests EA and EAC according to the modified Buescher method. A significantly lower percentage of neutrophils with FcR and CR receptors was found in patients with both insulin-dependent and noninsulin-dependent diabetes. The lowest values were found in noncompensated diabetes; in compensated diabetes they were higher but still significantly lower than in the controls. The difference was significant in both tests used. The results obtained suggest that the observed fall in the percentage of neutrophils with FcR and CR receptors is caused by metabolic disturbances associated with diabetes.
Zakład Immunopatologii AM w Białymstoku.
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Jabłońska
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Pietruska
D015932:Complement C3c; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D003924:Diabetes Mellitus, Type 2 / Q000276:immunology*; D006801:Humans; D009504:Neutrophils / Q000276:immunology*; D011951:Receptors, Complement / Q000032:analysis*; D017452:Receptors, IgG / Q000032:analysis*; D012397:Rosette Formation
D011951:Receptors, Complement; D017452:Receptors, IgG; D015932:Complement C3c
Zachowanie sie receptorów granulocytów dla fragmentu Fc Ig I składnika C3 dopełniacza u chorych z cukrzyca.