[Tropaphen in experimental drug therapy of cor pulmonale].
The influence of alpha-adrenoblocking drug tropaphen on cardio- and haemodynamics under experimental lung-heart failure was studied in dogs. The findings suggest effectiveness of tropaphen administration in such pathology shown by a decrease of lung hypertension and heart overload, significant increase of the contractile activity and relaxation properties of myocardium of both ventricles and in cardiac pump function optimization.
S B
SB
Frantsuzova
L L
LL
Arshinnikova
L I
LI
Antonenko
V P
VP
Iatsenko
D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D000818:Animals; D004285:Dogs; D005260:Female; D006321:Heart / Q000503:physiopathology; D006976:Hypertension, Pulmonary / Q000188:drug therapy; D008297:Male; D009200:Myocardial Contraction; D010276:Parasympatholytics / Q000627:therapeutic use*; D011660:Pulmonary Heart Disease / Q000188:drug therapy* / Q000503:physiopathology; D014326:Tropanes / Q000627:therapeutic use*
D000317:Adrenergic alpha-Antagonists; D010276:Parasympatholytics; D014326:Tropanes; C009599:tropodifene
Tropafen v éksperimenta'noĭ farmakoterapii legochnogo serdtsa.