Autologous graft engineering.
Autologous transplantation of bone marrow or peripheral blood stem cell preparations is now a widely used form of rescue from the myeloablative effects of high-dose therapy for malignant disease. The success of this procedure is affected by numerous factors associated both with management of the patient and the quality of the graft. In this review, approaches are described to maximize the success and utility of this therapeutic approach.
Gulati
S C
SC
Department of Hematologic Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY.
D001698:Biomedical Engineering; D016465:Bone Marrow Purging / Q000379:methods; D016026:Bone Marrow Transplantation / Q000379:methods*; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006801:Humans; D014182:Transplantation, Autologous