Medical therapy in Crohn's disease.
Traditionally, sulfasalazine and corticosteroids have been used to treat Crohn's disease. However, therapy has been expanded to include other drugs, and several newer agents show clinical promise. The authors discuss the therapeutic options now available and describe results of several drug trials. Despite the apparent benefits of newer therapies, caution must be used in choosing appropriate treatment.
Rogers
A I
AI
Veterans Affairs Medical Center, Miami, FL 33125.
Coelho-Borges
S
S
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003424:Crohn Disease / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D015201:Meta-Analysis as Topic; D012074:Remission Induction / Q000379:methods; D012460:Sulfasalazine / Q000031:analogs & derivatives / Q000737:chemistry / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D007166:Immunosuppressive Agents; D012460:Sulfasalazine