Macrophage- and lymphocyte-subtypes in the endometrium during different phases of the ovarian cycle.
The presence of immunocompetetive cells in the endometrium during the proliferative and secretory phase of the ovarian cycle is demonstrated on the light and electron microscopic level using monoclonal antibodies (MoAb). Subtypes of monocytes, macrophages and T-lymphocytes appear during the different phases in variable extent and different localization. Some subpopulations of the monocyte/macrophage system and T-helper lymphocytes increase in number on day 21/22. Our observations indicate that cells with bone marrow origin take part in functional events of the endometrium during the ovarian cycle.
Department of Obstetrics and Gynaecology, University of Kiel, Germany.
G
G
Bonatz
M L
ML
Hansmann
F
F
Buchholz
L
L
Mettler
H J
HJ
Radzun
K
K
Semm
D000911:Antibodies, Monoclonal; D015704:CD4 Antigens / Q000276:immunology; D016827:CD8 Antigens / Q000276:immunology; D004717:Endometrium / Q000033:anatomy & histology / Q000276:immunology* / Q000648:ultrastructure; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007121:Immunocompetence; D007150:Immunohistochemistry; D016131:Lymphocyte Subsets / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D008597:Menstrual Cycle / Q000276:immunology*
D000911:Antibodies, Monoclonal; D015704:CD4 Antigens; D016827:CD8 Antigens