Effects of ecdysteroids on reproductive physiology of Nippostrongylus brasiliensis (Nematoda) in vivo.
1. The influence of ecdysteroids (ecdysone and ecdysterone) was investigated on the control of reproduction in the parasitic nematode Nippostrongylus brasiliensis in vivo. 2. Infestive larvae (L3) were immersed in solutions of ecdysteroids (2.2 microM) at 37 degrees C for 4 hr before injection into the host. The effect on egg-laying was observed two stages later. 3. The treatment increased egg-laying, but had no influence on the timing of the reproductive period. The greatest effect was observed with ecdysone, ecdysterone only inducing a small and non-significant stimulation under our experimental conditions. 4. The physiological role of ecdysteroids in meiosis and gonadal development in nematodes is discussed.
Laboratoire de Biologie et Contrôle des Organsimes parasites, Faculté de Pharmacie de l'Université de Paris Sud, France.
F
F
Goudey-Perriere
B F
BF
Simo
J
J
Maccario
C
C
Perriere
P
P
Gayral
D000818:Animals; D004440:Ecdysone / Q000494:pharmacology*; D004441:Ecdysterone / Q000494:pharmacology*; D005260:Female; D007814:Larva / Q000187:drug effects / Q000502:physiology; D009559:Nippostrongylus / Q000187:drug effects* / Q000502:physiology; D010058:Oviposition / Q000187:drug effects; D012098:Reproduction / Q000187:drug effects
D004440:Ecdysone; D004441:Ecdysterone