[Endogenous humoral regulators directly before an operation].
It has been shown that modern premedication techniques do not prevent the activation of the sympathoadrenal system and the enhanced synthesis of cyclic nucleotides and prostaglandin-like compounds in response to preoperative stress. In a great number of patients there are no hemodynamic shifts in the nearest preoperative period, as an increased production of prostaglandins E and cyclic nucleotides (cAMP), that is of compensatory value, is observed. When normal relations between endogenous vasoactive substances with constricting and dilating effects are damaged, a hyperdynamic reaction ensures.
G N
GN
Gimmel'farb
N V
NV
Beletskaia
D000293:Adolescent; D000328:Adult; D000368:Aged; D001782:Blood Donors; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D018377:Neurotransmitter Agents / Q000097:blood*; D011229:Preanesthetic Medication / Q000379:methods / Q000706:statistics & numerical data; D013514:Surgical Procedures, Operative / Q000706:statistics & numerical data
D018377:Neurotransmitter Agents
Endogennye gumoral'nye reguliatory neposredstvenno pered operatsieĭ.