Non-specific immunity in patients with primary anogenital warts treated with interferon alpha plus cryotherapy or cryotherapy alone.
Combination treatment of primary anogenital warts with subcutaneous interferon alpha 2a plus cryotherapy was no more efficacious than cryotherapy alone. Patients with primary AG warts showed no in vitro or in vivo suppression of non-specific immunity. In patients treated with interferon plus cryotherapy non-specific cellular immunity was stimulated, both in vitro and in vivo compared with patients treated with cryotherapy alone.
Handley
J M
JM
Department of Genitourinary Medicine, Royal Victoria Hospital, Belfast, Northern Ireland.
Maw
R D
RD
Horner
T
T
Lawther
H
H
McNeill
T
T
Dinsmore
W W
WW
D000293:Adolescent; D000328:Adult; D001005:Anus Neoplasms / Q000276:immunology / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D003218:Condylomata Acuminata / Q000276:immunology / Q000601:surgery / Q000628:therapy*; D003452:Cryosurgery; D005260:Female; D005833:Genital Neoplasms, Female / Q000276:immunology / Q000601:surgery / Q000628:therapy*; D005834:Genital Neoplasms, Male / Q000276:immunology / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007113:Immunity, Innate; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins
D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins