Oxytocin and vasopressin change the activity of the contractile vacuole in Tetrahymena: newer contributions to the phylogeny of hormones and hormone receptors.
1. Primary interaction with oxytocin accounted for a significant prolongation of the time interval between two systolic contractions of the contractile vacuole in Tetrahymena, whereas primary interaction with vasopressin had no appreciable influence on that functional parameter. 2. Primary treatment (imprinting) with vasopressin increased sensitivity to vasopressin and reduced responsiveness to oxytocin. 3. Primary treatment (imprinting) with oxytocin did not increase cellular response either to oxytocin or to vasopressin on second exposure. 4. Oxytocin, which is chemically related to the antidiuretic hormone vasopressin, influences the water metabolism in protozoa; vasopressin develops a similar effect after imprinting. 5. The experimental observations allow conclusions on certain events involved in the phylogenesis of hormones and receptors.
Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.
G
G
Csaba
P
P
Kovács
D000818:Animals; D007447:Invertebrate Hormones / Q000235:genetics* / Q000378:metabolism; D010121:Oxytocin / Q000494:pharmacology*; D010802:Phylogeny; D011956:Receptors, Cell Surface / Q000235:genetics*; D013768:Tetrahymena / Q000166:cytology*; D014617:Vacuoles / Q000187:drug effects*; D014667:Vasopressins / Q000494:pharmacology*
D007447:Invertebrate Hormones; D011956:Receptors, Cell Surface; D014667:Vasopressins; D010121:Oxytocin