Stimulation of corticosterone secretion by dietary histidine in rats.
1. Liver glycogen accumulated within 3 days after the initiation of a histidine-excess diet. Serum corticosterone increased and serum insulin decreased, but plasma glucagon remained unchanged. 2. When 2 mmol (310 mg) of histidine was administered to fasted rats, serum corticosterone increased after 5 hr and tended to be higher 9 hr after administration. 3. Liver glycogen tended to accumulate after 5 hr and had accumulated significantly after 9 hr.
Department of Agricultural Chemistry, School of Agriculture, Nagoya University, Japan.
Y
Y
Aoyama
H
H
Sugiura
N
N
Amano
A
A
Yoshida
D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D002784:Cholesterol / Q000097:blood; D003345:Corticosterone / Q000097:blood / Q000378:metabolism*; D005934:Glucagon / Q000097:blood; D006639:Histidine / Q000008:administration & dosage*; D007328:Insulin / Q000097:blood; D008099:Liver / Q000502:physiology; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains
D001786:Blood Glucose; D007328:Insulin; D008112:Liver Glycogen; D006639:Histidine; D005934:Glucagon; D002784:Cholesterol; D003345:Corticosterone