[Thiamine Hydrochloride Reference Standard (Control 891) of National Institute of Hygienic Sciences].
The raw material of thiamine hydrochloride was examined for preparation of the "Thiamine Hydrochloride Reference Standard". Analytical results were as follows: melting point 242.7 degrees; pH 3.2 (1 g, water, 100 ml); IR spectrum the same as that of JP Reference Standard (Control: 841); one and two impurities detected by TLC and by HPLC analyses, respectively; assay by thiochrome method 100.3% and by HPLC 100.1% against the JP Reference Standard. Based on the results, the present raw material was authorized to be the Reference Standard of the National Institute of Hygienic Sciences.
S
S
Okada
R
R
Hiroshige
M
M
Tanaka
M
M
Murai
T
T
Kimura
D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D006077:Government Agencies; D006920:Hygiene; D007564:Japan; D010602:Pharmacopoeias as Topic; D013831:Thiamine / Q000302:isolation & purification / Q000592:standards*
D013831:Thiamine