[Morphologic characteristics of the liver allograft in experimental warm ischemia].
Thirty-minute normothermic liver ischemia causes swelling of the hepatocytes and sinusoid wall cells, their individual necrosis and discharge of the glycogen supply in the hepatocytes. The swelling of the hepatocytes and of the sinusoid wall cells causes a significant reduction of the liver lobe sinusoid volume which decreases from 27.6% to 5.4%, representing, actually, one fifth of the normal value. Such finding was recorded as a critical vascular liver volume, because any further decrease of the sinusoid volume would inevitably lead toward manifest and persisting portal hypertension which evidently interferes with Bernoulli trial of the hepatitic perfusion. The obtained data determine morphofunctional relevancy of the liver allograft for transplantation and are useful for all other surgical interventions requiring partial resection of this organ or time limited regional and total ischemia.
Institut za sudsku medicinu, Medicinski fakultet, Novi Sad.
R
R
Vuković
M
M
Simić
M
M
Tasić
S
S
Zivojinović
D000818:Animals; D004285:Dogs; D006801:Humans; D007511:Ischemia / Q000473:pathology*; D008099:Liver / Q000098:blood supply / Q000473:pathology*; D008102:Liver Circulation; D016031:Liver Transplantation; D013696:Temperature
Morfoloske karakteristike alografta jetre u eksperimentalnoj toploj ishemiji.