Origin and metabolism of serotonin.
A brief review is given of the distribution of serotonin in tissues. The enzymatic steps in the biosynthesis and metabolism of serotonin are described, and factors involved in the regulation of the in vivo metabolism of serotonin are reviewed.
Tyce
G M
GM
Department of Physiology and Biophysics, Mayo Clinic, Rochester, Minnesota 55905, USA.
D000818:Animals; D001142:Aromatic-L-Amino-Acid Decarboxylases / Q000378:metabolism; D006801:Humans; D012701:Serotonin / Q000096:biosynthesis / Q000378:metabolism*; D014365:Tryptophan Hydroxylase / Q000378:metabolism
D012701:Serotonin; D014365:Tryptophan Hydroxylase; D001142:Aromatic-L-Amino-Acid Decarboxylases