Production of recombinant proteins in serum-free media.
The advantages of serum-free culture for the manufacture of recombinant biopharmaceuticals from mammalian cells are reviewed. The process favoured is fed-batch serum-free cell culture. This process is applicable to the majority of cell lines, is practical on the large scale, gives the lowest manufacturing cost, and can be carried out without the use of any serum.
Broad
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D
Celltech Ltd., Slough, UK.
Boraston
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R
Rhodes
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M
D000818:Animals; D001769:Blood; D002460:Cell Line; D003470:Culture Media; D006801:Humans; D011994:Recombinant Proteins / Q000096:biosynthesis*
D003470:Culture Media; D011994:Recombinant Proteins