Genome type analysis of adenovirus type 4.
Twenty AV4 isolates were analysed with 18 restriction endonucleases. They could be classified into two genome types (genomic clusters) AV4p and AV4a. Combined with data from Li and Wadell [Arch Virol 1988;101:65-77], DNA variants p1-p8 and al-a3 were defined. The genetic relatedness within the genome types was in the range of 88-99% comigrating fragments, whereas < 62% of the fragments were comigrating between the genome types.
Adrian
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Institut für Virologie und Seuchenhygiene, Medizinische Hochschule Hannover, FRG.
D000260:Adenoviruses, Human / Q000145:classification / Q000235:genetics*; D015252:Deoxyribonucleases, Type II Site-Specific / Q000378:metabolism; D014644:Genetic Variation; D016679:Genome, Viral; D012150:Polymorphism, Restriction Fragment Length
D015252:Deoxyribonucleases, Type II Site-Specific