Phospholipid content of untreated and insulin treated cells of Neurospora crassa (wall-less strain).
Phosphatidylcholine (51.2%) and phosphatidyl-ethanolamine (38.3%) are the most abundant phospholipids in the wall-less strain of Neurospora crassa. Insulin treatment exerted no change on the amount of phosphoinositides, although some previous results proved the existence of specific insulin receptors and specific effect of insulin on glucose metabolism in these cells. Long (20 h) treatment with insulin also failed to cause biologically significant changes.
László
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Department of Biology, Semmelweis University Medical School, Budapest, Hungary.
Csaba
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D007328:Insulin / Q000494:pharmacology*; D009492:Neurospora crassa / Q000187:drug effects* / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000378:metabolism; D010714:Phosphatidylethanolamines / Q000378:metabolism; D010716:Phosphatidylinositols / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology
D007328:Insulin; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010716:Phosphatidylinositols; D010743:Phospholipids