Using fluorescence in situ hybridization (FISH) in genome mapping.
Fluorescence in situ hybridization (FISH) provides one of the most effective and rapid approaches for assigning and ordering DNA fragments within single eukaryotic chromosome bands. These techniques have wide applications not only for the mapping of the human genome and the genomes of other organisms, but also in clinical cytogenetics, somatic cell genetics, cancer diagnosis and gene expression studies.
Ahmanson Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA.
J R
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Korenberg
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T
Yang-Feng
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R
Schreck
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XN
Chen
D002874:Chromosome Mapping / Q000379:methods*; D015894:Genome, Human; D006801:Humans; D008856:Microscopy, Fluorescence; D009693:Nucleic Acid Hybridization