Neuropharmacology of pain.
Recent research on the site of action of morphine, its distribution following systemic administration and activity in a model of neuropathic pain is reviewed. Neuropeptides and pain is discussed in relation to tachykinins and their antagonists, cholecystokinin (CCK) and its antagonists and somatostatin.
Duggan
A W
AW
Department of Preclinical Veterinary Sciences, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Scotland, UK.
D000818:Animals; D002766:Cholecystokinin / Q000502:physiology; D004723:Endorphins / Q000502:physiology*; D006801:Humans; D009437:Neuralgia / Q000503:physiopathology; D009619:Nociceptors / Q000503:physiopathology*; D010146:Pain / Q000503:physiopathology*; D011942:Receptors, Adrenergic, alpha / Q000502:physiology; D011957:Receptors, Opioid / Q000502:physiology*; D012684:Sensory Thresholds / Q000502:physiology; D013004:Somatostatin / Q000502:physiology; D015320:Tachykinins / Q000502:physiology
D004723:Endorphins; D011942:Receptors, Adrenergic, alpha; D011957:Receptors, Opioid; D015320:Tachykinins; D013004:Somatostatin; D002766:Cholecystokinin