[Effect of thyroid hormones and diacylglycerols on sphingomyelin metabolism in liver cell nuclei in rats of various ages].
Sphingomyelin metabolism in liver cell nuclei of rats of various age has been studied. It was found that the level of sphingomyelin hydrolysis in cell nuclei is the highest in young animals, showing a decrease in 24-month-old animals. The age-specific fluctuations in the activity of phospholipase C may be one of possible reasons for sphingomyelinase activity changes in liver nuclei during ontogenesis. It has been shown that thyroid hormones and diacylglycerols control the sphingomyelinase activity in rat liver cells.
Babenko
N A
NA
Filonenko
N S
NS
D000375:Aging / Q000378:metabolism*; D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D004075:Diglycerides / Q000494:pharmacology*; D006868:Hydrolysis; D008099:Liver / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013109:Sphingomyelins / Q000378:metabolism*; D013961:Thyroid Gland / Q000502:physiology; D013963:Thyroid Hormones / Q000494:pharmacology*; D010738:Type C Phospholipases / Q000378:metabolism
D004075:Diglycerides; D013109:Sphingomyelins; D013963:Thyroid Hormones; D010738:Type C Phospholipases
Vliianie tireoidnykh gormonov i diatsilglitserinov na metabolizm sfingomielina v iadrakh kletok pecheni krys raznogo vozrasta.