Objective prick test evaluation: non-invasive techniques.
Prick test reactions are evaluated and quantified, comparing visual assessment with two non-invasive techniques: remittance spectroscopy and pulsed ultrasound for erythema and skin thickness measurements. Different information is provided by the two methods. Remittance spectroscopy discriminates well between negative and positive reactions (+ or ++), while failing to differentiate stronger reactions, where edema is a prominent feature. The latter reactions are better evaluated by skin thickness measurements, which, on the contrary, are less sensitive in revealing small skin thickness increases in weak reactions.
Berardesca
E
E
Department of Dermatology, University of Pavia IRCCS Policlinico S. Matteo, Italy.
Gabba
P
P
Nume
A
A
Rabbiosi
G
G
Maibach
H I
HI
D000328:Adult; D004487:Edema / Q000175:diagnosis* / Q000000981:diagnostic imaging; D004890:Erythema / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D012867:Skin / Q000000981:diagnostic imaging; D012882:Skin Tests; D012885:Skinfold Thickness; D013053:Spectrophotometry; D014463:Ultrasonography