Different expression of tyrosine aminotransferase and serine deydratase in rat livers after partial hepatectomy.
Tyrosine aminotransferase activity in rat liver increases during the first 24 hrs after partial hepatectomy with two peaks, one at 10 hrs and another at 18 hrs. This behaviour is due to an increase in TATmRNA synthesis. Expression of serine deydratase is also enhanced during the first 5 hrs after hepatectomy. It is suggested that the enhanced expression of the two genes is due to an increase in hormone incretion particularly glucagon and glucocorticoids.
Istituto di Patologia Generale, Università degli Studi di Perugia, Italy.
M A
MA
Della Fazia
G
G
Servillo
M
M
Viola-Magni
D000818:Animals; D006498:Hepatectomy; D007700:Kinetics; D012695:L-Serine Dehydratase / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D008115:Liver Regeneration; D008297:Male; D011061:Poly A / Q000235:genetics / Q000302:isolation & purification; D012313:RNA / Q000235:genetics / Q000302:isolation & purification; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014444:Tyrosine Transaminase / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism*
D012333:RNA, Messenger; D011061:Poly A; D012313:RNA; D014444:Tyrosine Transaminase; D012695:L-Serine Dehydratase