[In situ hybridization: a principle and method].
We describe the principle and method of in situ hybridization (ISH), detecting neurotransmitters or neuromodulators and their related enzyme or receptor. Furthermore, we overview recent research reports focused on the gene expression of dopamine receptors. ISH technique has been applied and is one of the most powerful strategies in the biological research field of psychiatry.
Department of Psychiatry, Kyoto Prefectural University of Medicine, Japan.
K
K
Fukui
H
H
Utsumi
T
T
Nakajima
D000818:Animals; D006801:Humans; D017403:In Situ Hybridization / Q000379:methods*; D018377:Neurotransmitter Agents / Q000032:analysis; D012333:RNA, Messenger / Q000032:analysis*; D011954:Receptors, Dopamine / Q000235:genetics*
D018377:Neurotransmitter Agents; D012333:RNA, Messenger; D011954:Receptors, Dopamine