[Splenic artery thrombosis with Adepal. Pathogenic role of anti-ethinylestradiol antibody?].
We report a case of splenic artery thrombosis developed in a 54-year old woman after prolonged use of oral contraceptives. The diagnosis of the disease, difficult on clinical grounds, was confirmed by computerized tomography and selective arteriography. The presence of anti-ethinyloestradiol antibodies in the serum is suspected to be a risk factor for thrombosis associated with oral contraception.
Service de Médecine Interne, Centre Hospitalier Lyon-Sud, Pierre Benite.
M M
MM
Thiébaut
R
R
Nové-Josserand
I
I
Durieu
D V
DV
Durand
R
R
Levrat
D000792:Angiography; D000906:Antibodies / Q000097:blood*; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects*; D004997:Ethinyl Estradiol / Q000009:adverse effects* / Q000276:immunology*; D019304:Ethinyl Estradiol-Norgestrel Combination; D005260:Female; D006801:Humans; D008875:Middle Aged; D009644:Norgestrel / Q000009:adverse effects*; D012307:Risk Factors; D013157:Splenic Artery; D013927:Thrombosis / Q000097:blood* / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000453:epidemiology; D014057:Tomography, X-Ray Computed
D000906:Antibodies; D003278:Contraceptives, Oral, Hormonal; D009644:Norgestrel; D004997:Ethinyl Estradiol; D019304:Ethinyl Estradiol-Norgestrel Combination
Thrombose de l'artère splénique sous Adépal. Rôle pathogène d'anticorps anti-éthinylestradiol?