Does chloroquine cause seizures? Presentation of three new cases and a review of the literature.
Three cases are reported of patients developing seizures whilst taking chloroquine. Recently, eight such cases have been reported elsewhere. A review of all patients described in the literature is given. Possible relationships between chloroquine and the occurrence of seizures are discussed and further studies recommended. At present we feel there is no need to restrict prescription of chloroquine to patients with a history of epilepsy.
Department of Neurology, Maastricht University Hospital, The Netherlands.
G J
GJ
Luijckx
M C
MC
De Krom
B C
BC
Takx-Kohlen
D000328:Adult; D002738:Chloroquine / Q000008:administration & dosage / Q000009:adverse effects*; D004569:Electroencephalography / Q000187:drug effects; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000188:drug therapy; D008288:Malaria / Q000517:prevention & control; D008297:Male; D013375:Substance Withdrawal Syndrome / Q000209:etiology
D002738:Chloroquine