Scammonins VII and VIII, two resin glycosides from Convolvulus scammonia.
Two minor ether-soluble resin glycosides, scammonins VII and VIII, were isolated from Radix Scammoniae, the roots of Convolvulus scammonia. In addition to (2S)-2-methylbutyric acid and tiglic acid, they are composed, respectively, of orizabic acid A and a new glycosidic acid named scammonic acid B, with similar macrocyclic ester structures to those of the scammonic acid A-based scammonins I-VI. Isolation of genuine scammonins III-V, which were previously obtained as peracetates, is also described.
Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan.
N
N
Noda
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H
Kogetsu
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T
Kawasaki
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K
Miyahara
D002240:Carbohydrate Sequence; D002851:Chromatography, High Pressure Liquid; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010944:Plants / Q000737:chemistry*; D012116:Resins, Plant / Q000737:chemistry* / Q000302:isolation & purification*
D006027:Glycosides; D012116:Resins, Plant; C076295:scammonin VIII; C076294:scammonin VII