Escherichia coli in fecal flora of healthy adults: serotypes, P and type 1C fimbriae, non-P mannose-resistant adhesins, and hemolytic activity.
Escherichia coli strains from feces of 287 healthy adults were analyzed for O:K serotypes, P and type 1C fimbriae, non-P mannose-resistant adhesins, and hemolysin production. O1, O2, O6, O7, O18, O25, and rough-type lipopolysaccharide accounted for 40% of all isolates. K antigen was present in 62%; K1 was identified in 30% and K5 in 10%. O1, O2, O18, rough lipopolysaccharide, and P fimbriation were significantly associated with K1 and O6, O25, and type 1C fimbriation with K5. The overall prevalence of virulence-associated determinants was 22%; 7% of the strains possessed two or three of them. These determinants were most often associated with 9 serotypes (O1:K1, O2:K1, O6:K1, O6:K5, O7:K1, O16:K1, O22:K-, O25:K5, and R:K1) among which their prevalence was 43%, three times greater than among the remaining strains (P < .001). No enteropathogenic or enterohemorrhagic E. coli-associated serotypes were detected.
Siitonen
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E. coli Laboratory, National Public Health Institute, Helsinki, Finland.
D018829:Adhesins, Bacterial; D000328:Adult; D004926:Escherichia coli / Q000145:classification* / Q000302:isolation & purification* / Q000648:ultrastructure; D005243:Feces / Q000382:microbiology*; D010861:Fimbriae, Bacterial / Q000648:ultrastructure*; D006460:Hemolysin Proteins / Q000032:analysis; D006461:Hemolysis; D006801:Humans; D008358:Mannose; D011135:Polysaccharides, Bacterial / Q000032:analysis*; D012016:Reference Values; D012703:Serotyping; D014774:Virulence
D018829:Adhesins, Bacterial; D006460:Hemolysin Proteins; D011135:Polysaccharides, Bacterial; C055239:bacterial adhesins, polysaccharide; D008358:Mannose