Using chromosome features in genome mapping.
Studies of the structure and function of chromosomal features and sequence elements have much to contribute to and gain from genome mapping. Abnormalities in chromosome banding associated with specific diseases have pinpointed regions of the genome for intensive analysis. An improved understanding of chromosome organization can facilitate gene identification and isolation, as well as enabling sophisticated genetic and vector systems for genome studies to be devised.
MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK.
H
H
Cooke
D000818:Animals; D002874:Chromosome Mapping / Q000379:methods*; D002875:Chromosomes / Q000648:ultrastructure*; D016678:Genome; D006801:Humans