[A case of locally advanced esophageal cancer effectively treated with concurrent chemotherapy and radiotherapy].
A case of a 69-year-old man with locally advanced esophageal cancer was reported. The patient received five courses of chemotherapy consisting of cisplatin (30 mg i.v. days 1-5), 5-fluorouracil (500 mg i.v. days 1-5) and bleomycin (5 mg i.m. days 1-5) every four weeks with a split course irradiation at a dose of 50 Gy, which was concurrently given at the second, third and fourth course of the chemotherapy. Treatment was effectively carried out without severe toxicities. The patient achieved a histologically-confirmed complete remission after completion of the treatment. The patient is disease-free and fully active 28 months after the beginning of chemotherapy. The treatment modality appears to be useful for advanced esophageal cancer.
Second Dept. of Internal Medicine, Dept. of Radiology, Okayama University Medical School, Japan.
Y
Y
Segawa
T
T
Ohnoshi
H
H
Ueoka
K
K
Kiura
T
T
Horiguchi
T
T
Kodani
H
H
Kamei
M
M
Tabata
T
T
Shibayama
T
T
Maeda
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D004938:Esophageal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008297:Male; D011879:Radiotherapy Dosage
D001761:Bleomycin; D002945:Cisplatin; D005472:Fluorouracil