FK 506 and cyclosporine inhibit antigen- or mitogen-induced monokine and lymphokine production in vitro.
Department of Immunology, Arrhenius Laboratories for Natural Sciences, Stockholm University, Sweden.
J
J
Andersson
S
S
Nagy
C G
CG
Groth
U
U
Andersson
D002478:Cells, Cultured; D016572:Cyclosporine / Q000494:pharmacology*; D016207:Cytokines / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D004305:Dose-Response Relationship, Drug; D004768:Enterotoxins / Q000494:pharmacology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007371:Interferon-gamma / Q000096:biosynthesis; D007376:Interleukin-2 / Q000096:biosynthesis; D015847:Interleukin-4 / Q000096:biosynthesis; D015848:Interleukin-5 / Q000096:biosynthesis; D015759:Ionomycin / Q000494:pharmacology*; D007700:Kinetics; D007963:Leukocytes, Mononuclear / Q000187:drug effects* / Q000276:immunology; D008222:Lymphokines / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D008233:Lymphotoxin-alpha / Q000096:biosynthesis; D013211:Staphylococcus aureus; D016559:Tacrolimus / Q000494:pharmacology*; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology*; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis
D016207:Cytokines; D004768:Enterotoxins; D007376:Interleukin-2; D015848:Interleukin-5; D008222:Lymphokines; D008233:Lymphotoxin-alpha; D014409:Tumor Necrosis Factor-alpha; D015847:Interleukin-4; C026066:enterotoxin A, Staphylococcal; D015759:Ionomycin; D007371:Interferon-gamma; D016572:Cyclosporine; D013755:Tetradecanoylphorbol Acetate; D016559:Tacrolimus