[Role of hyperbaric oxygenation in the treatment of acute anaerobic infections].
Hyperbaric oxygenation (HBO), as an adjuvant treatment in necrotizing soft tissues infections and in gas gangrene is reviewed, including its specific effects, experimental studies and clinical reports. With a global therapeutic management, considered as an emergency state, including surgery, antibiotic regimens and HBO, we can obtained 50% mortality and morbidity decrease with a more conservative surgery. Finally, favorable outcome is associated with early therapeutics and localization of the initial necrotizing infection.
Service d'Urgence respiratoire, de Réanimation médicale, et de Médecine hyperbare, hôpital Calmette, Lille.
F
F
Wattel
D
D
Mathieu
R
R
Neviere
J L
JL
Chagnon
D000208:Acute Disease; D001421:Bacteria, Anaerobic; D001424:Bacterial Infections / Q000628:therapy*; D003015:Clostridium Infections / Q000628:therapy; D003646:Debridement; D005734:Gangrene / Q000628:therapy*; D005738:Gas Gangrene / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D010406:Penicillins / Q000627:therapeutic use
D010406:Penicillins
Place de l'oxygénothérapie hyperbare dans le traitement des infections aiguës à germes anaérobies.