[Quantitative morpho- and densitometric parameters in the evaluation of aspiration cytology smears of the breast].
Quantitative morpho- and densitometric analysis of Feulgen stained breast aspiration smears were performed by absorption cytophotometer and a TV image analyser. The DNA Index, and the ratio of G1-S-G2 phase fraction ratio yielded by the quantitative DNA analysis, showed significant differences between benign and malignant alterations. Based on the 13 morphometric and 5 densitometric parameters the TV-image analyser could classify the examined smears 80% correctly by cluster analysis. Groups of the cytological Grade I.-III. were also differentiable by this method. The application of TV image analyser system in the diagnosis of aspiration cytological smears could be suggested. The complex quantitative morpho- and densitometric analysis could contribute to the correct classification of diploid tumours.
II. Belgyógyászati Klinika, Semmelweis Orvostudományi Egyetem, Budapest.
B
B
Molnár
Z
Z
Sápi
J
J
Meggyesi
J
J
Sugár
M
M
Bodó
J
J
Fehér
D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D003592:Cytophotometry; D004273:DNA, Neoplasm / Q000032:analysis; D003720:Densitometry; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D013194:Staining and Labeling / Q000379:methods; D013690:Television
D004273:DNA, Neoplasm
Quantitativ morfo- és densitometriai paraméterek az emlö aspirációs citológiai keneteinek kiértékelésében.