Pharmacological manipulation of tissue cyclic AMP by inhibitors. Effects of phosphodiesterase inhibitors on the functions of platelets and vascular endothelial cells.
Tokushima Research Institute, Otsuka Pharmaceutical Company, Ltd., Japan.
T
T
Tani
K
K
Sakurai
Y
Y
Kimura
T
T
Ishikawa
H
H
Hidaka
D015056:1-Methyl-3-isobutylxanthine / Q000494:pharmacology; D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases / Q000032:analysis / Q000037:antagonists & inhibitors* / Q000302:isolation & purification; D001792:Blood Platelets / Q000737:chemistry; D002478:Cells, Cultured; D000077407:Cilostazol; D000242:Cyclic AMP / Q000032:analysis*; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects*; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects*; D013777:Tetrazoles / Q000494:pharmacology*; D014470:Umbilical Cord; D014665:Vasodilator Agents / Q000494:pharmacology
D013777:Tetrazoles; D014665:Vasodilator Agents; D000242:Cyclic AMP; D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases; D000077407:Cilostazol; D015056:1-Methyl-3-isobutylxanthine