[Coma due to an overdose of valnoctamide].
We report a 27-year-old man, who became comatose after autopoisoning with a high dose of valnoctamide. He was mechanically ventilated for 12 hours and survived without serious side effects. Valnoctamide blood levels were monitored in order to study the pharmacokinetics of oral overdosing of this drug. Serum half-time levels appeared to be approximately 15 hours.
Ziekenhuis Leyenburg, afd. Interne Geneeskunde, 's-Gravenhage.
C F
CF
Melissant
A A
AA
Vinks
H P
HP
Sleeboom
D000328:Adult; D000577:Amides / Q000506:poisoning*; D014151:Anti-Anxiety Agents / Q000506:poisoning*; D003128:Coma / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008297:Male; D013406:Suicide, Attempted
D000577:Amides; D014151:Anti-Anxiety Agents; C045179:valnoctamide
Coma door overdosering van valnoctamide.