[Contribution of 99mTc MAG3 in hypertension in an elderly subject with renal artery thrombosis].
To ascertain the responsibility of renal artery thrombosis for the genesis of arterial hypertension, the methods available are not sufficiently sensitive and reproducible, and the residual revascularization maintained by a vicarious arterial network is not easy to demonstrate. Renal scintigraphy with technetium 99m-labelled mercaptoacetyltriglycine (MAG3) was performed in 4 old and severely hypertensive male patients with chronic thrombosis of one renal artery. With this tracer the thrombotic kidney was detected lately and weakly at the vascular and nephrographic stages. When the functions of both kidneys were compared, that of the affected kidney was always estimated at less than 5%. At the excretory stage a residual activity could be detected in the kidney with renal artery thrombosis. Owing to the specific biophysical behaviour of the tracer, MAG3 scintigraphy coupled with arteriography and assays of plasma renin activity in the veins contribute to the decision concerning nephrectomy.
Service de Médecine Interne, CHRU Hôpital Nord, Saint-Priest-en-Jarez.
R
R
Gonthier
J M
JM
Guy
J
J
Tostain
S
S
Charmion
X
X
Barral
H
H
Rousset
D000368:Aged; D000792:Angiography; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003131:Combined Modality Therapy; D006801:Humans; D006978:Hypertension, Renovascular / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D009392:Nephrectomy; D011866:Radioisotope Renography; D012078:Renal Artery Obstruction / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging* / Q000601:surgery; D012083:Renin / Q000097:blood; D012680:Sensitivity and Specificity; D017263:Technetium Tc 99m Mertiatide; D013927:Thrombosis / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging* / Q000601:surgery
D000959:Antihypertensive Agents; D017263:Technetium Tc 99m Mertiatide; D012083:Renin
Apport de la scintigraphie au 99mTc MAG3 dans l'HTA du sujet âgé avec thrombose d'une artère rénale.