An acute mercuric mercury poisoning: chemical speciation of hair mercury shows a peak of inorganic mercury value.
A woman ingested a dose of sublimate (approximately 0.9 g) in an attempted suicide. She survived and recovered in response to a combination of therapies including chelate (BAL) therapy, plasma exchange, haemodialysis and peritoneal dialysis. Serum inorganic mercury concentration, urinary inorganic mercury excretion and hair inorganic and organic mercury and selenium concentrations, along the length from the scalp to the distal part, were measured. Longitudinal analysis of hair, revealed a peak in inorganic mercury corresponding to the time of mercury ingestion. Organic mercury and selenium in the hair had different patterns of longitudinal variation from that of inorganic mercury. The biological half-life (23.5 d) of serum inorganic mercury levels was in good agreement with values previously reported in the literature.
Department of Human Ecology, Faculty of Medicine, University of Tokyo, Japan.
T
T
Suzuki
T
T
Hongo
N
N
Matsuo
H
H
Imai
M
M
Nakazawa
T
T
Abe
Y
Y
Yamamura
M
M
Yoshida
H
H
Aoyama
D000328:Adult; D005260:Female; D006197:Hair / Q000378:metabolism*; D006207:Half-Life; D006801:Humans; D008627:Mercuric Chloride / Q000378:metabolism / Q000506:poisoning*; D008628:Mercury / Q000378:metabolism; D009941:Organomercury Compounds / Q000378:metabolism; D012643:Selenium / Q000378:metabolism; D013405:Suicide
D009941:Organomercury Compounds; D008627:Mercuric Chloride; D008628:Mercury; D012643:Selenium