Lymphoid interstitial pneumonia not associated with HIV infection: role of Epstein-Barr virus.
The polymerase chain reaction (PCR) method was used to determine the presence of Epstein-Barr virus sequences in seven cases of pulmonary lymphoid interstitial pneumonia not associated with HIV infection. Evidence of Epstein-Barr virus genome was found in three of six cases in which beta-globin gene, used as an internal control for the integrity and amplifiability of the tissue DNA, could be detected. These results suggest that Epstein-Barr virus infection is not always required for the development of lymphoid interstitial pneumonia.
Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington, DC.
V
V
Malamou-Mitsi
M M
MM
Tsai
A A
AA
Gal
M N
MN
Koss
T J
TJ
O'Leary
D000328:Adult; D000368:Aged; D001483:Base Sequence; D017931:DNA Primers / Q000737:chemistry; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections; D006566:Herpesviridae Infections / Q000382:microbiology*; D004854:Herpesvirus 4, Human / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000382:microbiology*; D008232:Lymphoproliferative Disorders / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D015345:Oligonucleotide Probes / Q000737:chemistry; D016133:Polymerase Chain Reaction; D014412:Tumor Virus Infections / Q000382:microbiology*
D017931:DNA Primers; D015345:Oligonucleotide Probes