Cranial nerve involvement in childhood polyarteritis nodosa.
Amongst a variety of neurological manifestations of childhood polyarteritis nodosa, cranial nerve involvement is unusual. We report 4 cases with cranial nerve palsies in a series of 36 biopsy-proven patients. Two cases presented with IIIrd nerve palsy alone, one with right IIIrd and left IVth nerve palsy, and one with peripheral VIIth nerve paresis. All 4 patients showed good response to prednisolone and cyclophosphamide treatment. Cranial nerve involvement in childhood polyarteritis nodosa seems not so rare when patients are followed on long term basis.
Department of Pediatric Nephrology, Hacettepe University Children's Hospital, Ankara, Turkey.
R
R
Topaloglu
N
N
Besbas
U
U
Saatci
A
A
Bakkaloglu
A
A
Oner
D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003389:Cranial Nerve Diseases / Q000188:drug therapy / Q000235:genetics / Q000473:pathology*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000473:pathology; D009132:Muscles / Q000098:blood supply; D009460:Neurologic Examination / Q000187:drug effects; D010488:Polyarteritis Nodosa / Q000188:drug therapy / Q000235:genetics / Q000473:pathology*; D011239:Prednisolone / Q000008:administration & dosage; D012867:Skin / Q000098:blood supply
D003520:Cyclophosphamide; D011239:Prednisolone