Isolation and characterization of macrocarpals B--G antibacterial compounds from Eucalyptus macrocarpa.
Six novel phloroglucinol dialdehyde diterpene derivatives (macrocarpals B--G), which have antibacterial activity, were isolated from leaves of Eucalyptus macrocarpa. These compounds have closely related structures, the molecular formula for B--F being C28H40O6, and that of G being C28H38O5. The structures of macrocarpals B, D, and G were analyzed by means of NMR analyses.
Yamakoshi
Y
Y
Department of Nutrition and Food Science, Ochanomizu University, Tokyo, Japan.
Murata
M
M
Shimizu
A
A
Homma
S
S
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D004224:Diterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D005052:Eucalyptus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010696:Phloroglucinol / Q000031:analogs & derivatives / Q000302:isolation & purification* / Q000494:pharmacology; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology; D010946:Plants, Medicinal; D013056:Spectrophotometry, Ultraviolet; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D004224:Diterpenes; D010936:Plant Extracts; D010696:Phloroglucinol