[Clinical assessment of a group of children with juvenile rheumatoid arthritis receiving long-term treatment with oral gold salt].
The authors assess the efficacy of gold salt treatment for juvenile rheumatoid arthritis. The study was carried out on 16 children suffering from mono-pauciarticular, polyarticular and systemic arthritis. Treatment consisted of the administration of auranofin alone in a group of 8 children and auranofin associated to corticosteroids in a second group of 8 children. A marked improvement in clinical conditions was observed with slight transitory side effects at follow-up after 12 and 24 months.
III Divisione Universitaria di Pediatria, Università di Torino.
F
F
Mignone
M L
ML
Sardella
L
L
Clara
S
S
Barrett
R
R
Basano
I
I
Barbero
D000293:Adolescent; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001171:Arthritis, Juvenile / Q000628:therapy*; D001310:Auranofin / Q000009:adverse effects / Q000493:pharmacokinetics; D002648:Child; D002675:Child, Preschool; D004064:Digestive System / Q000187:drug effects; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006052:Gold Sodium Thiomalate / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008297:Male
D018501:Antirheumatic Agents; D006052:Gold Sodium Thiomalate; D001310:Auranofin
Valutazione clinica su un gruppo di bambini affetti da artrite reumatoide giovanile in terapia con sali d'oro orali a lungo termine.