[Vecuronium in pediatric anesthesia. Repeated bolus vs continuous infusion].
Vecuronium bromide was employed in 26 pediatric patients; 18 received vecuronium infusion and 11 intermittent bolus administration. The aim of the study was to evaluate the pharmacodynamics of the drug, the lack of cumulative properties, the best infusion rate, the possible advantage of the infusion technique. Neuromuscular blockade monitoring was performed in all patients. In the results, vecuronium shows lack of cumulative properties. The best infusion rate was 0.13 +/- 0.02 mg/kg/h. The continuous infusion allows the employment of lesser doses of the drug than the intermittent administration.
Istituto di Anestesiologia e Rianimazione, Università di Bari.
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G
Barbone
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G
Longo
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F
Bruno
D000293:Adolescent; D000771:Anesthesia, Intravenous / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007275:Injections, Intravenous; D008297:Male; D014673:Vecuronium Bromide / Q000008:administration & dosage*
D014673:Vecuronium Bromide
Il vecuronio in anestesia pediatrica. Boli ripetuti vs infusione continua.