Mastoparan, via a GTP binding protein, activates apical chloride and potassium conductances, decreases cell volume, and increases permeability of cultured epithelial cell monolayers.
University of Iowa, Iowa City.
M
M
Winter
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M
Carson
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Shasby
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D002463:Cell Membrane Permeability / Q000187:drug effects*; D002478:Cells, Cultured; D002712:Chlorides / Q000378:metabolism*; D004285:Dogs; D004594:Electrophysiology; D004847:Epithelial Cells; D004848:Epithelium / Q000502:physiology; D006160:Guanosine Triphosphate / Q000494:pharmacology*; D036341:Intercellular Signaling Peptides and Proteins; D007473:Ion Channels / Q000187:drug effects / Q000378:metabolism; D007668:Kidney; D010455:Peptides; D011188:Potassium / Q000378:metabolism*; D014862:Wasp Venoms / Q000494:pharmacology*
D002712:Chlorides; D036341:Intercellular Signaling Peptides and Proteins; D007473:Ion Channels; D010455:Peptides; D014862:Wasp Venoms; C037500:mastoparan; D006160:Guanosine Triphosphate; D011188:Potassium