Studies to define viral cofactors for human immunodeficiency virus.
Results from molecular biologic, cell biologic and animal experiments show that HIV replication can be driven by a variety of other viruses. If such interactions took place in vivo, then they could help to explain some of the complex pathogenesis of AIDS. The problems incurred in attempting to address this question in populations of humans are discussed.
Division of Communicable Diseases, Royal Free Hospital School of Medicine, London, United Kingdom.
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Griffiths
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology; D000818:Animals; D006678:HIV / Q000235:genetics / Q000502:physiology; D015658:HIV Infections / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D011961:Receptors, Fc / Q000378:metabolism; D015163:Superinfection / Q000382:microbiology; D015533:Transcriptional Activation; D014777:Virus Diseases / Q000382:microbiology; D014779:Virus Replication
D011961:Receptors, Fc