Survey of drug-related deaths in Victoria.
OBJECTIVE
To audit drug-related deaths to determine the types of agents causing death in Victoria and to identify possible strategies for prevention of deaths in future.


METHODS
Retrospective audit of Coroner's case records.


METHODS
All deaths reported to the Coroner during 14 months from 1 July 1989 to 31 August 1990 in Victoria in which toxicological investigation was undertaken and drugs or poisons were detected and were believed to be a major cause of death.


RESULTS
Of the 231 people who had drug-related deaths, 156 were males, 75 were females and the average age was 35.5 +/- 14 years. Heroin and morphine were judged to be the primary cause of death in 35% of subjects and methadone in a further 4.8%. Tricyclic antidepressants were responsible for 14% of deaths, with no deaths due solely to mianserin. Benzodiazepines were the prime cause of death in 6.5% of subjects, but were identified in 40%. Poisons and chemicals were involved in only 3% of deaths. Prescription drugs were primarily responsible for 47% of deaths. Forty-eight per cent of deaths occurred in known injecting drug users and 42% of all subjects had a clear history of antecedent depression. Only one drug-related death was clearly accidental, that of a two-year-old child taking his parents' medications, but the mode of most deaths was not clear, and may not have been suicide. Most deaths occurred outside hospital, only 25 subjects reaching hospital alive.


CONCLUSIONS
Barbiturates and chloral hydrate are no longer major causes of drug-related deaths, probably because of decreased availability. Some drug-related deaths, especially those related to tricyclic antidepressants, may be prevented if deaths and hospitalisations due to toxic substances are monitored and the availability and scheduling of toxic substances are regularly reviewed.
Coleridge
J
J
Emergency Department, Western Hospital, Footscray, VIC.
Cameron
P A
PA
Drummer
O H
OH
McNeil
J J
JJ
D000293:Adolescent; D000328:Adult; D000368:Aged; D014151:Anti-Anxiety Agents / Q000506:poisoning; D000928:Antidepressive Agents / Q000506:poisoning; D000929:Antidepressive Agents, Tricyclic / Q000506:poisoning; D001569:Benzodiazepines; D062787:Drug Overdose; D011307:Drug Prescriptions; D005260:Female; D006801:Humans; D013287:Illicit Drugs / Q000506:poisoning; D008297:Male; D008875:Middle Aged; D004366:Nonprescription Drugs / Q000506:poisoning; D011041:Poisoning / Q000401:mortality*; D012189:Retrospective Studies; D015819:Substance Abuse, Intravenous / Q000401:mortality; D013405:Suicide; D014739:Victoria / Q000453:epidemiology
D014151:Anti-Anxiety Agents; D000928:Antidepressive Agents; D000929:Antidepressive Agents, Tricyclic; D013287:Illicit Drugs; D004366:Nonprescription Drugs; D001569:Benzodiazepines