Four new bioactive polyhydroxylated sterols from the black coral Antipathes subpinnata.
Four new polyoxygenated sterols 2-5 were isolated from the marine black coral Antipathes subpinnata. The structures of these compounds, including stereochemical details, were deduced by ms, 1H- and 13C-nmr, 1H-1H COSY, and nOe difference spectroscopy. Compounds 2-5 are lethal to brine shrimp (Artemia salina).
Aiello
A
A
Dipartimento di Chimica delle Sostanze Naturali, Napoli, Italy.
Fattorusso
E
E
Menna
M
M
D000818:Animals; D002775:Cholestadienols / Q000302:isolation & purification* / Q000633:toxicity; D002783:Cholestenones / Q000302:isolation & purification* / Q000633:toxicity; D003063:Cnidaria / Q000737:chemistry*; D033364:Decapoda / Q000502:physiology*; D007928:Lethal Dose 50; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013261:Sterols / Q000302:isolation & purification* / Q000633:toxicity
D002775:Cholestadienols; D002783:Cholestenones; D013261:Sterols