Novel applications of the ubiquitin-dependent proteolytic pathway in plant genetic engineering.
One goal of plant genetic engineering is the manipulation of protein levels within crop plants. New insights into the ubiquitin-dependent proteolytic pathway provide potential novel ways of enhancing levels of desired proteins by synthesizing them as ubiquitin fusions, and reducing levels of undesired proteins by selective protein degradation. As a result, the ubiquitin pathway should become a useful tool for many aspects of plant biotechnology.
Hondred
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Department of Horticulture, University of Wisconsin, Madison 53706.
Vierstra
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D000595:Amino Acid Sequence; D010450:Endopeptidases; D006868:Hydrolysis; D008969:Molecular Sequence Data; D010944:Plants / Q000737:chemistry / Q000235:genetics*; D015202:Protein Engineering / Q000379:methods*; D014452:Ubiquitins / Q000737:chemistry / Q000235:genetics*
D014452:Ubiquitins; D010450:Endopeptidases