Increased tardive dyskinesia in alcohol-abusing schizophrenic patients.
Many schizophrenics have a diagnosis of substance abuse or dependence. We evaluated whether drug or alcohol abuse is an independent risk factor for tardive dyskinesia (TD) in schizophrenia. In a consecutive admission, clinical study of 75 hospitalized schizophrenics, drug or alcohol abusers had significantly higher TD scores than nonabusers. The association of alcohol abuse or dependence with TD seemed independent from other risk factors for TD.
Dixon
L
L
Department of Psychiatry, Payne Whitney Clinic, New York Hospital-Cornell Medical Center, NY.
Weiden
P J
PJ
Haas
G
G
Sweeney
J
J
Frances
A J
AJ
D000328:Adult; D000437:Alcoholism / Q000150:complications* / Q000175:diagnosis; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy*
D014150:Antipsychotic Agents