Vitamin C regulation of cartilage maturation.
Treatment of chondrocytes with vitamin C under defined conditions in cell culture initiates a differentiation program that closely mimics the normal maturation of cells in the growth plate of long bones.
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology*; D002356:Cartilage / Q000166:cytology* / Q000187:drug effects*; D002454:Cell Differentiation / Q000502:physiology; D002478:Cells, Cultured; D002642:Chick Embryo; D002645:Chickens; D003094:Collagen / Q000096:biosynthesis
D003094:Collagen; D001205:Ascorbic Acid