Effects of benzodiazepine receptor ligands with different intrinsic activities on seizures induced by inhibition of GAD.
Research and Development Department, Ciba-Geigy Ltd., Basel, Switzerland.
R
R
Bernasconi
P
P
Martin
A F
AF
Steulet
C
C
Portet
T
T
Leonhardt
M
M
Schmutz
D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D002243:Carbolines / Q000494:pharmacology; D003975:Diazepam / Q000494:pharmacology; D005442:Flumazenil / Q000494:pharmacology; D005968:Glutamate Decarboxylase / Q000037:antagonists & inhibitors* / Q000502:physiology; D006624:Hippocampus / Q000187:drug effects / Q000503:physiopathology; D007538:Isoniazid / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011720:Pyrazoles / Q000494:pharmacology; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology; D011963:Receptors, GABA-A / Q000187:drug effects* / Q000502:physiology; D012640:Seizures / Q000139:chemically induced* / Q000503:physiopathology; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
D014151:Anti-Anxiety Agents; D002243:Carbolines; D011720:Pyrazoles; D011963:Receptors, GABA-A; C034818:methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate; D005442:Flumazenil; D005680:gamma-Aminobutyric Acid; C034704:2-(4-chlorophenyl)-2,5-dihydropyrazolo(4,3-c)quinoline-3(3H)-one; D005968:Glutamate Decarboxylase; D003975:Diazepam; D007538:Isoniazid