[Fluocinolone Acetonide Reference Standard (Control 901) of the National Institute of Hygienic Sciences)].
Fluocinolone Acetonide Reference Standard (Control 901) for the Japanese Pharmacopoeia (JP RS) was prepared. The following analytical data were obtained: melting point 268 degrees C (decomposition); IR spectrum was same as the previous JP RS of Fluocinolone Acetonide; absorptivity at 237nm E1%1lcm = 363; optical rotation [alpha]20D = 105.7 degrees; no impurity was detected by TLC, but two impurities were detected by HPLC analysis; assay by HPLC against the previous JP RS 100.2%. Based on the above results, this raw material was authorized as the Reference Standard of the National Institute of Hygienic Sciences.
H
H
Kakehi
M
M
Murai
H
H
Komatsu
S
S
Ishimitsu
S
S
Okada
D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D005446:Fluocinolone Acetonide / Q000302:isolation & purification / Q000592:standards*; D006077:Government Agencies; D006920:Hygiene; D007564:Japan; D010602:Pharmacopoeias as Topic
D005446:Fluocinolone Acetonide