Constitutional translocation (8;13) in a patient with non-Hodgkin's lymphoma.
We report a case of non-Hodgkin's lymphoma in a 16-year-old male, whose peripheral white blood cells have a t(8;13)(q24;q14). There are no previous reports that describe this association. Although the tumor cells were not studied, we discuss the possible link between this finding and the development of the malignant lymphoma.
Department of Cytogenetic, Instituto Nacional de Cancerología, México City, Mexico.
M T
MT
Salles
O
O
Neyra
L
L
Taja
G
G
Cervantes
M
M
Gagnière
M
M
Cerrillo
A
A
Mohar
A
A
Osornio
E
E
Reynoso
G
G
Gorodezky
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D001853:Bone Marrow / Q000473:pathology; D002871:Chromosome Banding; D002882:Chromosomes, Human, Pair 13; D002898:Chromosomes, Human, Pair 8; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D007621:Karyotyping; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D008297:Male; D011241:Prednisone / Q000008:administration & dosage; D014178:Translocation, Genetic; D014750:Vincristine / Q000008:administration & dosage
D001761:Bleomycin; D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone