Role of lipid peroxidation and antioxidants in aging process and thalassemia.
Oxygen free radicals and other oxygen derived species (Superoxide, O2-; Hydroperoxide, HOO; Singlet oxygen, 1O2-; Hydroxyl radical, OH; and Hydrogen peroxide, H2O2) including lipid peroxides have been suggested as important causative agents of aging and several human diseases, including cancer, multiple sclerosis, Parkinson's disease, autoimmune disease, ischemia, anemia, senile dementia, asbestosis and in thalassemia. This paper aims to communicate some of the theories and rationales in aging process and thalassemia.
Chanarat
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Department of Clinical Chemistry, Faculty of Associated Medical Sciences, Chiang Mai University, Thailand.
D000375:Aging / Q000378:metabolism*; D000975:Antioxidants / Q000494:pharmacology; D005609:Free Radicals; D006801:Humans; D015227:Lipid Peroxidation; D015995:Prevalence; D017382:Reactive Oxygen Species / Q000378:metabolism; D013785:Thailand / Q000453:epidemiology; D013789:Thalassemia / Q000453:epidemiology / Q000378:metabolism*; D014810:Vitamin E / Q000097:blood
D000975:Antioxidants; D005609:Free Radicals; D017382:Reactive Oxygen Species; D014810:Vitamin E