Non-aqueous enzymology.
Compelling evidence has been obtained during the past year that enzymes retain their native active-site structure in organic solvents, and yet the properties of the solvent significantly affect enzyme kinetics. Fundamental advances in enzymatic catalysis in monophasic organic media are discussed and selected applications in the areas of asymmetric, polymer and chemoenzymatic syntheses are highlighted.
Dordick
J S
JS
University of Iowa, Iowa City.
D001665:Binding Sites; D004798:Enzymes / Q000378:metabolism*; D012997:Solvents
D004798:Enzymes; D012997:Solvents