Germinal and somatic mutation induction in Drosophila after treatment of larvae with tritiated water.
The present study was carried out to evaluate the mutagenicity of tritium, administered as tritiated water, in Drosophila melanogaster. Larvae were fed on tritium-treated medium during their development. Germinal and somatic mutation induction was detected by means of the sex-linked recessive lethal and the wing spot tests, respectively. Our results show that beta-radiation from tritium is able to induce significant increases in the frequency of both germinal and somatic mutations.
Departament de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain.
G
G
Ribas
C
C
Torres
M
M
Batiste-Alentorn
N
N
Xamena
A
A
Creus
R
R
Marcos
D000818:Animals; D004331:Drosophila melanogaster / Q000187:drug effects / Q000235:genetics / Q000528:radiation effects*; D005020:Ethyl Methanesulfonate / Q000494:pharmacology; D005804:Genes, Lethal; D005808:Genes, Recessive; D007814:Larva; D016296:Mutagenesis; D009152:Mutagenicity Tests; D014316:Tritium / Q000494:pharmacology*; D014867:Water / Q000494:pharmacology*
D014867:Water; D014316:Tritium; C033961:tritium oxide; D005020:Ethyl Methanesulfonate