Advances in neuropharmacological rehabilitation for brain dysfunction.
The use of pharmacological agents as rehabilitative tools following brain injury remains to some degree both a science and an art. Recent work in the area of the neural sciences has shed new light on the workings of basic CNS neurochemical systems and the use of pharmacologic agents in altering central neurophysiologic processes. The major central neurochemical systems are reviewed both anatomically and physiologically. An overview is provided of basic neuropharmacologic agents by class. Lastly, some of the newer neuropharmacological options for treatment of post-acute brain injury deficits are examined.
Department of Rehabilitation Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298.
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Zasler
D001921:Brain / Q000187:drug effects* / Q000503:physiopathology; D001925:Brain Damage, Chronic / Q000503:physiopathology / Q000534:rehabilitation*; D001930:Brain Injuries / Q000503:physiopathology / Q000534:rehabilitation*; D002491:Central Nervous System Agents / Q000627:therapeutic use*; D006801:Humans; D018377:Neurotransmitter Agents / Q000502:physiology*; D017981:Receptors, Neurotransmitter / Q000187:drug effects* / Q000502:physiology
D002491:Central Nervous System Agents; D018377:Neurotransmitter Agents; D017981:Receptors, Neurotransmitter