A farnesyl arabinoside as an enhancer of glucose transport in rat adipocytes from a soft coral, Sinularia sp.
Separation of a lipophilic extract of a soft coral, Sinularia sp., assayed by enhancement of glucose transport in rat adipocytes, gave farnesyl 4-O-beta-D-arabinopyranosyl-beta-D-arabinopyranoside-2,2',3- triacetate (1a) whose structure was determined by spectroscopy. Enhancers of glucose transport may be useful for the prevention and treatment of diabetic disorders.
New Lead Research Laboratories, Sankyo Co. Ltd., Tokyo, Japan.
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Shindo
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Sato
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Horikoshi
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Kuwano
D000273:Adipose Tissue / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D003063:Cnidaria / Q000737:chemistry*; D005204:Farnesol / Q000494:pharmacology*; D005947:Glucose / Q000378:metabolism*; D051381:Rats; D012503:Saponins / Q000494:pharmacology*; D013729:Terpenes
D012503:Saponins; D013729:Terpenes; C075933:farnesyl 4-O-arabinopyranosyl-arabinopyranoside-2,2',3-triacetate; D005204:Farnesol; D005947:Glucose