Parasitological diagnosis of schistosomiasis mansoni: fecal examination and rectal biopsy.
Even with all progress in the search of sensitive and specific methods for the immunological diagnosis of schistosomiasis, the microscopic detection of eggs of the parasite in the stool still remains the most widely used tool for the actual diagnosis of active infection. Among the coproscopic methods, Kato's technic modified by Katz et al (Kato/Katz) has the advantages of higher sensitivity, the possibility of egg quantification, its low operational cost and its feasibility in areas with minimal infra-structure. The oogram of the rectal mucosa is valuable in initial clinical trials of schistosomicides, when it is needed to observe egg morphology in tissue. It could be an alternative method for individual diagnosis, being more sensitive than a single stool exam in low intensity infection. However, the increased sensitivity of a higher number of fecal exams makes that invasive procedure unnecessary. In the assessment of cure of schistosomiasis, Kato/Katz method (three fecal samples in one, three and six months after treatment) and the rectal biopsy four months after treatment, are equally reliable.
Centro de Pesquisas René Rachou-FIOCRUZ, Belo Horizonte, MG, Brasil.
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D000818:Animals; D001706:Biopsy; D005243:Feces / Q000469:parasitology; D006801:Humans; D010063:Ovum / Q000648:ultrastructure; D010270:Parasite Egg Count / Q000379:methods; D012007:Rectum / Q000469:parasitology* / Q000473:pathology; D012550:Schistosoma mansoni / Q000302:isolation & purification; D012555:Schistosomiasis mansoni / Q000175:diagnosis* / Q000469:parasitology