The importance of targeting the CD4+ T cell subset at the time of antigenic challenge for induction of prolonged vascularized allograft survival.
Sablinski
T
T
Harvard Medical School, Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts.
Sayegh
M H
MH
Kut
J P
JP
Tilney
N L
NL
Milford
E L
EL
Kupiec-Weglinski
J W
JW
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D000941:Antigens / Q000276:immunology*; D000945:Antigens, Differentiation, T-Lymphocyte / Q000502:physiology; D017252:CD3 Complex; D015704:CD4 Antigens / Q000502:physiology; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D006085:Graft Survival; D016027:Heart Transplantation; D007165:Immunosuppression Therapy / Q000379:methods*; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D011948:Receptors, Antigen, T-Cell / Q000502:physiology; D014184:Transplantation, Homologous
D000911:Antibodies, Monoclonal; D000941:Antigens; D000945:Antigens, Differentiation, T-Lymphocyte; D017252:CD3 Complex; D015704:CD4 Antigens; D011948:Receptors, Antigen, T-Cell