[Endoscopic ultrasonographic study of gastric ulcer treated with proton pump inhibitor].
We examined 70 cases of gastric ulcer by endoscopic ultrasonography. Of these, 18 cases were treated with proton pump inhibitor (PPI), another cases were treated with histamine H2 receptor antagonist or mucosal protective drugs. The Endoscopic cumulative healing rate at the eighth week was 71.4% in all gastric ulcers. On the other hand, all of gastric ulcers treated with PPI were healed within eight weeks endoscopically. Gastric ulcers which were revealed ultrasonographically to be refractory with were healed by PPI therapy. The length of the ulcer echo in gastric ulcers treated with PPI was shorter than that in gastric ulcer treated by other drugs. In spite of endoscopic scar findings, a wide ulcer echo was observed in some cases.
Department of Internal Medicine, Second Hospital, Fujita Health University.
J
J
Yoshino
S
S
Nakazawa
T
T
Nakamura
K
K
Yamao
K
K
Inui
H
H
Yamachika
K
K
Watanabe
T
T
Wakabayashi
D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors*; D000328:Adult; D000368:Aged; D005260:Female; D005773:Gastroscopy; D017506:H(+)-K(+)-Exchanging ATPase; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009853:Omeprazole / Q000494:pharmacology / Q000627:therapeutic use*; D013276:Stomach Ulcer / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D014463:Ultrasonography
D006635:Histamine H2 Antagonists; D000251:Adenosine Triphosphatases; D017506:H(+)-K(+)-Exchanging ATPase; D009853:Omeprazole