[Influence of normovolemic hemodilution on the respiratory and circulatory systems].
We studied respiratory and circulatory kinetics of normovolemic hemodilution in adult mongrel dogs. The dogs were divided into two groups; Dextran-40 (group A) and SALIN-HES (group B). No difference in PaO2 and PaCO2 was noted between the two groups. MPA and CI during normovolemic hemodilution were higher in group A than in group B. However, MPA, Qs/Qt and ETVI during normovolemic hemodilution were largely influenced in group A. L/P during normovolemic hemodilution was more influenced in group B than in group A. The compensatory effect with increase of the cardiac output during normovolemic hemodilution was noted until S3 (Hct = 10%), but it was not noted at S4 (Hct = 5%) and S5 (just before death). SvO2 is the most sensitive index indicating the risk of normovolemic hemodilution.
Kobori
M
M
Department of Anesthesiology, School of Medicine, Showa University, Tokyo.
Negishi
H
H
Hosoyamada
A
A
D000818:Animals; D003911:Dextrans; D004285:Dogs; D006438:Hemodilution; D006439:Hemodynamics / Q000502:physiology*; D006895:Hydroxyethyl Starch Derivatives; D012119:Respiration / Q000502:physiology*
D003911:Dextrans; D006895:Hydroxyethyl Starch Derivatives