Eye lesions, blindness and visual impairment in the Taraba river valley, Nigeria and their relation to onchocercal microfilariae in skin.
2876 persons in fourteen communities in the Taraba River Valley, Nigeria were examined for eye lesions and tested for visual acuity using the 'tumbling E'. The individuals were also examined for microfilaria of Onchocerca volvulus. More than one-tenth of the population were blind, while another 16.1% had visual impairment. The prevalence of blindness was in excess of 20% in six communities, with one community recording 71.9% blindness rate. All forms of visual involvement increased with age but were similar between sexes. Eye lesions were related to the level of vision. Both eye lesions and vision deteriorate with increase in age. Vision seems to worsen with increase in prevalence and intensity of O. volvulus. Large microfilarial loads were associated with severe eye damage and blindness. These findings indicate that the Taraba river valley could be one of West Africa's worst foci of onchocercal blindness.
Department of Biological Sciences, Federal University of Technology, Yola, Nigeria.
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Akogun
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000818:Animals; D001766:Blindness / Q000453:epidemiology* / Q000469:parasitology; D002648:Child; D002675:Child, Preschool; D003316:Corneal Diseases / Q000453:epidemiology* / Q000469:parasitology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008842:Microfilariae / Q000302:isolation & purification; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D009854:Onchocerca / Q000302:isolation & purification; D015827:Onchocerciasis, Ocular / Q000453:epidemiology* / Q000469:parasitology; D015995:Prevalence; D012876:Skin Diseases, Parasitic / Q000453:epidemiology / Q000469:parasitology; D014786:Vision Disorders / Q000453:epidemiology* / Q000469:parasitology; D014792:Visual Acuity