Protein folding in vitro.
It is becoming increasingly evident that intermediates observed in protein folding in vitro may be closely related to conformational states that are important in various intracellular processes. This review focuses on recent advances in in vitro protein-folding studies with particular reference to the molten globule state, which is purported to be a common and distinct intermediate of protein folding.
Kuwajima
K
K
Department of Physics, Faculty of Science, University of Tokyo, Japan.
D000818:Animals; D001709:Biotechnology; D006801:Humans; D066298:In Vitro Techniques; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D013816:Thermodynamics