Short-acting beta-adrenergic blockade and the fetus. A case report.
An infant was born to a woman who received intravenous esmolol for intrapartum supraventricular tachyarrhythmia. Despite the very short acting and cardio-selective beta-1 adrenergic blockade induced by that agent, neonatal effects can occur up to 48 hours after delivery.
Gilson
G J
GJ
Department of Obstetrics and Gynecology, University of New Mexico Hospital, Albuquerque 87131.
Knieriem
K J
KJ
Smith
J F
JF
Izquierdo
L
L
Chatterjee
M S
MS
Curet
L B
LB
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D000328:Adult; D005260:Female; D005311:Fetal Hypoxia / Q000139:chemically induced*; D006801:Humans; D007275:Injections, Intravenous; D007744:Obstetric Labor Complications / Q000175:diagnosis / Q000188:drug therapy*; D011247:Pregnancy; D011412:Propanolamines / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D013617:Tachycardia, Supraventricular / Q000175:diagnosis / Q000188:drug therapy*
D000319:Adrenergic beta-Antagonists; D011412:Propanolamines; C036604:esmolol