Inhibition of HIV-1 reverse transcriptase and virus replication by a non-nucleoside dipyridodiazepinone BI-RG-587 (Nevirapine).
Skoog
M T
MT
Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, Connecticut 06877.
Hargrave
K D
KD
Miglietta
J J
JJ
Kopp
E B
EB
Merluzzi
V J
VJ
D000818:Animals; D001381:Azepines / Q000378:metabolism / Q000494:pharmacology*; D001483:Base Sequence; D001665:Binding Sites; D015497:HIV-1 / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D008969:Molecular Sequence Data; D019829:Nevirapine; D011725:Pyridines / Q000378:metabolism / Q000494:pharmacology*; D018894:Reverse Transcriptase Inhibitors; D013329:Structure-Activity Relationship; D014779:Virus Replication / Q000187:drug effects*
D001381:Azepines; D011725:Pyridines; D018894:Reverse Transcriptase Inhibitors; D019829:Nevirapine