[Successfully treated locally advanced breast cancer by intra-arterial infusion chemotherapy: a case report].
A 40-year-old female was admitted to our hospital with a large right breast tumor that was over 15 cm in diameter. We treated this locally advanced breast cancer by intra-arterial infusion chemotherapy. Through a catheter placed in the right subclavian artery, doses of 20-30 mg of ADM were injected intermittently with MMC and 5-FU. When a total of 120 mg of ADM had been infused, leukopenia developed, but this was immediately improved by G-CSF. With this treatment, her breast tumor and lung metastases were almost completely disappeared. Thus, an intra-arterial infusion chemotherapy was considered to be an effective treatment for locally advanced breast cancer.
Dept. of Endocrine Surgery, Toranomon Hospital, Tokyo, Japan.
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N
Suzuki
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Nakazawa
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Akiyama
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D004317:Doxorubicin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage; D006801:Humans; D007261:Infusions, Intra-Arterial; D016685:Mitomycin / Q000008:administration & dosage; D013348:Subclavian Artery
D016179:Granulocyte Colony-Stimulating Factor; D016685:Mitomycin; D004317:Doxorubicin; D005472:Fluorouracil