Cell metabolism measurements in culture via microelectronic biosensors.
Silicon-based H(+)-sensitive biosensors in proximity to a cell population detect variations in cell metabolism via local measurements of changes in pH. The feasibility of this approach is shown in the case of ISFET devices.
Grattarola
M
M
Biophysical and Electronic Engineering Department, University of Genova, Italy.
Martinoia
S
S
Carlini
G
G
Cambiaso
A
A
Tedesco
M
M
Parodi
M T
MT
Ferri
G
G
D015374:Biosensing Techniques; D002477:Cells / Q000378:metabolism*; D002478:Cells, Cultured; D005069:Evaluation Studies as Topic; D006863:Hydrogen-Ion Concentration; D014173:Transistors, Electronic