[Anesthetic management of a hemophilia A carrier for palliative operation and radical repair of a cardiac anomaly].
We experienced the anesthetic management of a hemophilia A carrier for two palliative operations (left and right unifocalization) and radical repair of cardiac anomaly. The patient was a ten-year-old girl and her father had hemophilia A. She was diagnosed as tetralogy of Fallot, major aortopulmonary collateral arteries and pulmonary atresia. Laboratory findings showed prolonged bleeding time and activated partial thromboplastin time, and decreased levels of factor VIII activity of 26%. When she was eight and nine years old, she underwent unifocalization. At both occasions, excessive bleeding tendency continued into postoperative period. This time she underwent radical repair in which her bleeding tendency was successfully controlled by use of a usual dose of concentrated factor VIII for twice.
Department of Anesthesiology, Tokyo Women's Medical College.
H
H
Nakajima
K
K
Takada
A
A
Taguchi
I
I
Kondou
C
C
Tsunoda
K
K
Nishiyama
M
M
Nomura
K
K
Shirai
M
M
Fujita
D002353:Carrier State; D002648:Child; D005169:Factor VIII / Q000627:therapeutic use*; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications / Q000601:surgery*; D006467:Hemophilia A / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D010166:Palliative Care
D005169:Factor VIII