Population genetics and forensic efficiency data of 4 AMPFLP's.
Family studies were carried out in a population sample from north west Germany using 4 amplifiable VNTR polymorphic systems D1S80 (MCT118), ApoB, D17S30 (YNZ22) and COL2A1. Separation was carried out in polyacrylamide gels and visualised using silver staining. In family studies (n = 30) no evidence of new mutations was found. The population study of unrelated individuals (mothers and putative fathers) showed that all 4 systems were highly polymorphic and similar to other population studies. The combined exclusion chance was calculated to be approximately 99% and the combined discrimination index 1.5.10(-4). The Hardy-Weinberg equilibrium was checked by forming groups of alleles and no significant deviations could be found in all systems.
Institut für Rechtsmedizin, Westfälische Wilhelms Universität Münster, Federal Republic of Germany.
S
S
Rand
C
C
Puers
K
K
Skowasch
P
P
Wiegand
B
B
Budowle
B
B
Brinkmann
D000483:Alleles; D002874:Chromosome Mapping; D004247:DNA / Q000235:genetics*; D005260:Female; D005784:Gene Amplification / Q000235:genetics*; D005787:Gene Frequency / Q000235:genetics*; D005828:Genetics, Population; D005858:Germany; D006801:Humans; D008297:Male; D010334:Paternity; D016133:Polymerase Chain Reaction / Q000379:methods*; D012150:Polymorphism, Restriction Fragment Length; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics
D004247:DNA