Gastroscopic evaluation of the effects of nabumetone on the gastrointestinal mucosa of rheumatic patients.
Endoscopic studies with nabumetone have consistently shown a lower incidence of gastro-duodenal erosive lesions than comparable non-steroidal anti-inflammatory drugs (NSAIDs) including naproxen and ibuprofen.
Gastroenterology Unit, L Sacco Hospital, Milan, Italy.
G
G
Bianchi Porro
M
M
Petrillo
S
S
Ardizzone
I
I
Caruso
F
F
Montone
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D002074:Butanones / Q000009:adverse effects* / Q000627:therapeutic use; D018849:Controlled Clinical Trials as Topic; D004064:Digestive System / Q000187:drug effects* / Q000473:pathology; D005773:Gastroscopy; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects / Q000627:therapeutic use; D000077430:Nabumetone; D009288:Naproxen / Q000009:adverse effects / Q000627:therapeutic use; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D012216:Rheumatic Diseases / Q000188:drug therapy*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D002074:Butanones; D009288:Naproxen; D000077430:Nabumetone; D007213:Indomethacin