Fatal myocardial infarction and use of psychotropic drugs in young women.
We have observed an unexpected 17-fold increase in risk of fatal [corrected] myocardial infarction (relative risk 16.9, 95% confidence interval 3.9-72.8) associated with current use of psychotropic drugs. This incidental finding, in a case-control study of cardiovascular mortality in women aged 16-39 not designed to test any hypothesis about psychotropic drugs, should be treated cautiously. There is, however, evidence of a relation between psychiatric morbidity and cardiovascular disease and the association recorded here requires further investigation.
Department of Public Health and Primary Care, University of Oxford, UK.
M
M
Thorogood
P
P
Cowen
J
J
Mann
M
M
Murphy
M
M
Vessey
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000401:mortality; D011619:Psychotropic Drugs / Q000009:adverse effects*; D012307:Risk Factors; D013345:Subarachnoid Hemorrhage / Q000139:chemically induced; D013924:Thrombophlebitis / Q000139:chemically induced; D006113:United Kingdom / Q000453:epidemiology
D011619:Psychotropic Drugs