Methylbromide intoxication: a case report.
This work focuses on the neurophysiological features in a patient with action myoclonus and mental deterioration following methylbromide intoxication. The patient is a 28-year-old man, without respiratory distress or exposure to other toxics. Myoclonus improved with polytherapy (clonazepam, 5-HT, carbidopa, GABA). The neurophysiological and neuropsychological evidence in this patient suggests a possible double site of action of methylbromide at cortical and subcortical levels.
Clinica del Lavoro Foundation Medical Center of Rehabilitation, Institute of Care and Research, Veruno, Italy.
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L
Mazzini
M
M
Galante
M
M
Rezzonico
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A
Kokodoko
D000328:Adult; D002230:Carbidopa / Q000008:administration & dosage; D002998:Clonazepam / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D004569:Electroencephalography / Q000187:drug effects; D004831:Epilepsies, Myoclonic / Q000139:chemically induced / Q000175:diagnosis / Q000523:psychology; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced / Q000175:diagnosis / Q000523:psychology; D005071:Evoked Potentials / Q000187:drug effects; D006801:Humans; D006842:Hydrocarbons, Brominated / Q000506:poisoning*; D008297:Male; D009207:Myoclonus / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D011930:Reaction Time / Q000187:drug effects; D019966:Substance-Related Disorders / Q000175:diagnosis* / Q000523:psychology
D006842:Hydrocarbons, Brominated; D002998:Clonazepam; C005218:methyl bromide; D002230:Carbidopa