Development of hepatic microsomal activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the young chick.
1. The 3-hydroxy-3-methylglutaryl-CoA reductase activity increased from 1 to 4 weeks of age, but decreased from 4 to 8 weeks of age. 2. Cholesterol 7 alpha-hydroxylase activity increased from 1 to 4 weeks, decreased from 4 to 6 weeks, and increased again from 6 to 8 weeks of age. 3. Serum total and free cholesterol concentrations decreased from 1 to 6 weeks of age, but increased from 6 to 8 weeks of age.
Department of Biochemistry and Molecular and Cellular Biology, University College of La Rioja, University of Zaragoza, Logroño, Spain.
P
P
Iñarrea
E
E
Villareal
I
I
Moya
P
P
Aguirre
J
J
Palacios
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002645:Chickens; D002784:Cholesterol / Q000097:blood; D002790:Cholesterol 7-alpha-Hydroxylase / Q000378:metabolism*; D004032:Diet; D006903:Hydroxymethylglutaryl CoA Reductases / Q000378:metabolism*; D008055:Lipids / Q000097:blood; D008862:Microsomes, Liver / Q000201:enzymology*; D010743:Phospholipids / Q000097:blood; D014280:Triglycerides / Q000097:blood
D001786:Blood Glucose; D008055:Lipids; D010743:Phospholipids; D014280:Triglycerides; D002784:Cholesterol; D006903:Hydroxymethylglutaryl CoA Reductases; D002790:Cholesterol 7-alpha-Hydroxylase