Patient tolerance of ioxaglate and iopamidol in internal mammary artery arteriography.
To compare discomfort caused by ioxaglate and iopamidol, 25 patients scheduled for coronary angiography including internal mammary arteriography were studied. Each patient received both agents. Data were available on 22 randomly selected patients who completed the protocol. Two patients were withdrawn because of unsuccessful internal mammary artery cannulation and one because of idiosyncratic reaction to diazepam. After the internal mammary artery injections, the short-form McGill Pain Questionnaire (SF-MPQ) was completed to evaluate the patient response. Ioxaglate caused significantly less discomfort than iopamidol. Word scale (WS) p less than .05; visual analog scale (VAS) p less than .05. We conclude that ioxaglate is much better tolerated than iopamidol in internal mammary arteriography.
Maritime Heart Center, Victoria General Hospital, Dalhousie University, Halifax, Nova Scotia, Canada.
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Miller
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Knox
D000328:Adult; D000368:Aged; D000792:Angiography; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000601:surgery; D003973:Diatrizoate / Q000009:adverse effects; D005260:Female; D006801:Humans; D007479:Iopamidol / Q000009:adverse effects*; D007485:Ioxaglic Acid / Q000009:adverse effects*; D008297:Male; D008323:Mammary Arteries / Q000000981:diagnostic imaging*; D008875:Middle Aged; D009204:Myocardial Revascularization; D010147:Pain Measurement; D010342:Patient Acceptance of Health Care
D003973:Diatrizoate; D007479:Iopamidol; D007485:Ioxaglic Acid