Distinct responses of interleukin-6 and other laboratory parameters to treatment in a patient with polyarteritis nodosa--a case report.
The authors describe a patient in whom the serum levels of interleukin-6 (IL-6) and other laboratory parameters were monitored. The IL-6 and C-reactive protein (CRP) levels, which were extremely high before treatment, declined rapidly with administration of prednisolone. Rheumatoid factor, IgG, and platelets count declined more gradually. Thus, determination of the serum IL-6 level might be useful in diagnosing and monitoring polyarteritis nodosa.
Department of Medicine, Kansai Rosai Hospital, Hyogo, Japan.
H
H
Nakahama
M
M
Okada
M
M
Miyazaki
N
N
Imai
T
T
Yokokawa
S
S
Kubori
D000368:Aged; D002097:C-Reactive Protein / Q000032:analysis; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D015850:Interleukin-6 / Q000097:blood*; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D010976:Platelet Count / Q000187:drug effects; D010488:Polyarteritis Nodosa / Q000097:blood* / Q000188:drug therapy / Q000276:immunology; D011239:Prednisolone / Q000494:pharmacology / Q000627:therapeutic use*; D012217:Rheumatoid Factor / Q000097:blood
D007074:Immunoglobulin G; D015850:Interleukin-6; D002097:C-Reactive Protein; D012217:Rheumatoid Factor; D011239:Prednisolone