On hypotensive action of some imidazoline derivatives of sulphonamidated aryloxyalkylcarboxylic acids.
New imidazolines derived from sulphonamidated aryloxyalkylcarboxylic acids have been tested for their antihypertensive action and toxicity. The obtained results attest a remarkable biological action, low toxicity and a good absorption in oral administration.
Soldea
C
C
Oniscu
C
C
Sunel
V
V
D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology* / Q000633:toxicity; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D007093:Imidazoles / Q000494:pharmacology* / Q000633:toxicity; D007928:Lethal Dose 50; D051379:Mice; D009025:Morpholines / Q000494:pharmacology* / Q000633:toxicity; D013329:Structure-Activity Relationship
D000959:Antihypertensive Agents; D007093:Imidazoles; D009025:Morpholines