Lovastatin in the treatment of hypercholesterolemia in CAPD.
The authors studied the effect of lovastatin on five hypercholesterolemic CAPD patients with high risk of atherosclerotic cardiovascular disease. Patients took lovastatin 20 mg once daily for a mean period of 4.5 months. Pre- and post-treatment values of LDL and VLDL totals (325 mg/dl and 292 mg/dl, respectively) and of HDL (42 mg/dl and 43 mg/dl, respectively) had no significant statistical difference. Lack of significance may be due to low number of patients and short trial time. The study did demonstrate that lovastatin is well tolerated in CAPD patients.
Krane
N K
NK
Tulane University School of Medicine, Department of Medicine, New Orleans, Louisiana.
Stock
G
G
Caballero
M
M
Starks
E
E
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy* / Q000209:etiology; D008148:Lovastatin / Q000627:therapeutic use*; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*
D008148:Lovastatin