[A case of verrucous carcinoma of the tongue, effectively treated with preoperative chemotherapy (UFT, CDDP, PEP) and irradiation].
A 70-year-old male complained of a mass on the left side of his tongue. A biopsy specimen was diagnosed as verrucous carcinoma. He was treated with preoperative chemotherapy (UFT, CDDP, PEP) and irradiation, continuous partial glossectomy. The tumor response to chemotherapy was excellent, and no tumor cells were found in the surgical specimen. There was no recurrence of the tumor 1 year and 7 months after therapy. For advanced tumors, preoperative chemotherapy appears to be significantly effective.
Dept. of Dentistry and Oral Surgery, Hirosaki University School of Medicine, Japan.
J
J
Tanaka
K
K
Yoshida
M
M
Takahashi
M
M
Suzuki
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002291:Carcinoma, Papillary / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D017663:Peplomycin; D011300:Preoperative Care; D011879:Radiotherapy Dosage; D005641:Tegafur / Q000008:administration & dosage; D014062:Tongue Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D014498:Uracil / Q000008:administration & dosage
D001761:Bleomycin; D005641:Tegafur; D017663:Peplomycin; D014498:Uracil; D002945:Cisplatin