[The effect of glycoside Tripterygium wilfordii Hook F on the immune regulatory function of T lymphocyte].
Previously, we treated successfully patients with systemic lupus erythromatosus (SLE) with glycoside Tripterygium Wilfordii Hook F, a Chinese medicinal herb. To evaluate the pharmacological mechanism of this herb, we studied its effects on the activation and proliferation facets of human T lymphocyte in vitro. The results revealed that this drug can markedly suppress the activation and proliferation facets of T lymphocytes.
Jiang
M
M
Department of Medicine, Peking Union Medical College Hospital, Beijing.
D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology*; D006027:Glycosides / Q000494:pharmacology; D006801:Humans; D007376:Interleukin-2 / Q000096:biosynthesis; D013601:T-Lymphocytes / Q000166:cytology / Q000187:drug effects* / Q000276:immunology*; D029757:Tripterygium
D004365:Drugs, Chinese Herbal; D006027:Glycosides; D007376:Interleukin-2