[The use of the bromocriptine test in schizophrenia patients resistant to neuroleptic therapy].
To choose differentiated therapy, 62 patients suffering from refractory schizophrenia were administered bromocriptine in a dose of 7.5-15 mg/day after they had been placed on placebo. According to the bromocriptine test, the treatment was changed in 53 patients. After the occurrence of the picture of hallucinatory stupor remission was attained with the aid of less doses of neuroleptics given before. In patients who responded to bromocriptine by anxious excitation, the health status noticeably improved after administration of anxiolytics and lithium carbonate. Those patients in whom bromocriptine eliminated psychosis were treated later with the drugs belonging to the group of monosubstituted benzamides.
Ryzhakov
B A
BA
Nuller
I U
IU
D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000037:antagonists & inhibitors*; D001971:Bromocriptine / Q000008:administration & dosage; D002908:Chronic Disease; D004351:Drug Resistance; D006801:Humans; D011954:Receptors, Dopamine / Q000187:drug effects; D012559:Schizophrenia / Q000175:diagnosis* / Q000188:drug therapy
D014150:Antipsychotic Agents; D011954:Receptors, Dopamine; D001971:Bromocriptine
Primenenie bromkriptinovogo testa u bol'nykh shizofrenieĭ, rezistentnykh k terapii neĭroleptikami.