Incidence of congenital uterine anomalies in repeated reproductive wastage and prognosis for pregnancy after metroplasty.
To discover the exact incidence of congenital uterine anomalies among infertile patients, hysterosalpingography was performed on 1,200 married women with a history of repeated reproductive wastage. Out of 1,200 hysterosalpingographies, 188 revealed congenital uterine anomaly (15.7%). The degree of uterine cavity deformity in the anomalies was evaluated during hysterosalpingography using the X/M ratio. This indicated that the incidence of repeated spontaneous abortion in cases with low-grade anomalies is as high as the incidence among cases with more severe anomalies. A significant improvement in maintaining pregnancy was observed after metroplasty; more than 84% of postoperative pregnancies were successfully maintained, whereas none of the 233 presurgical pregnancies had lasted full term. As a control group, 47 other women with anomalies were randomly chosen, and their subsequent pregnancies were monitored, without metroplasty. Of their pregnancies, 94.4% terminated spontaneously before 12 weeks of gestation.
Makino
T
T
Department of Obstetrics and Gynecology, School of Medicine, Keio University, Tokyo, Japan.
Umeuchi
M
M
Nakada
K
K
Nozawa
S
S
Iizuka
R
R
D000026:Abortion, Habitual / Q000209:etiology*; D005260:Female; D006801:Humans; D007047:Hysterosalpingography; D011247:Pregnancy; D011256:Pregnancy Outcome; D011379:Prognosis; D014599:Uterus / Q000002:abnormalities* / Q000601:surgery