[Studies on the quality of enzyme preparations (XI)--Kallidinogenase preparations].
Qualitative tests of 22 kinds of commercially available kallidinogenase preparations were carried out by the enzymological method. These preparations consisted of 16 kinds of tablets, 5 kinds of capsules and 1 kind of ampoule. One sample of tablet showed kallidinogenase activity less than 80% of the labeled amount by spectrophotometry, pH stat and kinin-liberating methods. All other preparations were found to have 90-120% 120% of the labeled amount by spectrophotometry using S-2266 as the substrate. Other enzymes, i.e. kininase, trypsin and chymotrypsin were found as impurities, but the cntants were very low.
T
T
Tanimoto
M
M
Ohta
N
N
Kawasaki
A
A
Tanaka
D004304:Dosage Forms; D007610:Kallikreins / Q000032:analysis / Q000592:standards*; D011786:Quality Control; D013053:Spectrophotometry
D004304:Dosage Forms; D007610:Kallikreins