Cell metabolism measurements in culture via microelectronic biosensors.
Silicon-based H(+)-sensitive biosensors in proximity to a cell population detect variations in cell metabolism via local measurements of changes in pH. The feasibility of this approach is shown in the case of ISFET devices.
Biophysical and Electronic Engineering Department, University of Genova, Italy.
M
M
Grattarola
S
S
Martinoia
G
G
Carlini
A
A
Cambiaso
M
M
Tedesco
M T
MT
Parodi
G
G
Ferri
D015374:Biosensing Techniques; D002477:Cells / Q000378:metabolism*; D002478:Cells, Cultured; D005069:Evaluation Studies as Topic; D006863:Hydrogen-Ion Concentration; D014173:Transistors, Electronic