[Neuromediator adaptation of the cerebral cortex and brain stem structures after radiation exposure].
In experiments with male Wistar rats a decreased receptor binding of 3H-corticosterone and impairment of neuromediator adaptation in the brain structures responsible for the regulation of animal and vegetative functions were observed 6 months after the effect of external radiation (0.5 Gy) and a mixture of external radiation and 131I (6.5 microCi/kg). These processes, being partly arrested by neurotropin, lay the neurochemical basis for the development of diencephalic syndrome.
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D000222:Adaptation, Physiological; D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000324:Adrenocorticotropic Hormone / Q000032:analysis; D000818:Animals; D001933:Brain Stem / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000503:physiopathology*; D008297:Male; D018377:Neurotransmitter Agents / Q000502:physiology*; D011134:Polysaccharides / Q000494:pharmacology; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D051381:Rats; D011919:Rats, Inbred Strains; D011965:Receptors, Glucocorticoid / Q000032:analysis; D011987:Receptors, Steroid
D000276:Adjuvants, Immunologic; D018377:Neurotransmitter Agents; D011134:Polysaccharides; D011965:Receptors, Glucocorticoid; D011987:Receptors, Steroid; C024357:corticosterone receptor; C010491:neurotropin; D000324:Adrenocorticotropic Hormone
Neĭromediatornaia adaptatsiia v kore i strukturakh stvolovoĭ chasti mozga pri radiatsionnom vozdeĭstvii.