Possible mechanism of sustained neuronal death induced by excessive glutamate and endogenous glutamate release; its protection by flunarizine and presence of glia cells in cultured cerebellar granule cells.
Department of Pharmacology, Tokyo Medical College, Japan.
Y
Y
Watanabe
T
T
Shibuya
D016923:Cell Death / Q000187:drug effects; D002478:Cells, Cultured; D002531:Cerebellum / Q000166:cytology* / Q000187:drug effects; D003594:Cytoplasmic Granules / Q000187:drug effects; D005444:Flunarizine / Q000494:pharmacology*; D005971:Glutamates / Q000633:toxicity*; D018698:Glutamic Acid; D005998:Glycine / Q000378:metabolism; D006801:Humans; D009457:Neuroglia / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D016875:tau Proteins / Q000378:metabolism
D005971:Glutamates; D016875:tau Proteins; D018698:Glutamic Acid; D005444:Flunarizine; D005998:Glycine