Indirect evaluation of blood oximetry by digitized conjunctival capillarography: effects of naftidrofuryl.
Microcirculatory disturbances are essential elements in peripheral and visceral oxygenation. Microcirculation can be studied by conjunctival angioscopy with morphological studies (arterioles, veinules, and capillaries appearances) and blood flow dynamics by digitized photographies (indirect oxymetric measurements in vivo). We studied the effects of naftidrofuryl on 20 atherosclerotic patients (mean 70 years old). After 3 months' treatment some parameters were significantly improved: interstitial edema, arteriolar sludge, and mainly vascular oxymetry. This means better microcirculatory hemodynamics and thus a better tissular oxygenation.
Department of Nephrology and Clinical Pharmacology, Höpital Henri Mondor, Créteil, France.
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Lagrue
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Questel
D000368:Aged; D017546:Angioscopy / Q000379:methods*; D002196:Capillaries / Q000648:ultrastructure; D003228:Conjunctiva / Q000098:blood supply*; D005069:Evaluation Studies as Topic; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D009257:Nafronyl / Q000494:pharmacology*; D010092:Oximetry
D009257:Nafronyl