Hypothalamic paraventricular nucleus plays a role in acupuncture analgesia through the central nervous system in the rat.
This work investigates the effect of hypothalamic paraventricular nucleus (PVN) on acupuncture analgesia in the rat. Electrical stimulation of PVN or injection of L-glutamate sodium into PVN could enhance the analgesic effect induced by acupuncture Zusanli (St. 36) while the electrical cauterization of PVN is decreased; Removal of the pituitary could not influence the effect of enhancing acupuncture analgesia induced by the injection of L-glutamate sodium into PVN. These results suggest that PVN might play an important role in acupuncture analgesia through central nervous system.
Dept. of Nuclear Medicine, Nan Fang Hospital, Guangzhao, China.
J
J
Yang
B C
BC
Lin
D015667:Acupuncture Analgesia; D000818:Animals; D004558:Electric Stimulation; D005971:Glutamates / Q000494:pharmacology; D018698:Glutamic Acid; D008297:Male; D010286:Paraventricular Hypothalamic Nucleus / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley
D005971:Glutamates; D018698:Glutamic Acid