Effect of glycol ethers on plasma osmolality.
1. Glycol ethers and their alkoxyacetic acid metabolites produce a linear increase in plasma osmolality with increasing plasma concentration. 2. This change in osmolality may be too small to be clinically useful at concentrations expected in cases of acute human glycol ether poisoning.
Browning
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RG
Department of Medical Toxicology, Good Samaritan Regional Medical Center, Phoenix, Arizona.
Curry
S C
SC
D000328:Adult; D000818:Animals; D005026:Ethylene Glycols / Q000378:metabolism / Q000506:poisoning*; D005260:Female; D006801:Humans; D009994:Osmolar Concentration; D010949:Plasma / Q000187:drug effects*
D005026:Ethylene Glycols