Stereoselective total synthesis of wheat flour ceramide dihexoside.
A plant glycosphingolipid, O-(beta-D-mannopyranosyl)-(1----4)-O-(beta-D-glucopyranosyl)-(1----1)-(2 S,3S,4R)-4-hydroxy-N-tetracosanoylsphinganine 1, and the stereoisomer, O-(alpha-D-mannopyranosyl)-(1----4)-O-(beta-d-glucopyranosyl)-(1----1)-( 2S,3S,4R)-4-hydroxy-N-tetracosanoylsphinganine 6, were synthesized in a stereo- and regio-controlled way.
Koike
K
K
College of Pharmacy, Nihon University, Chiba, Japan.
Mori
M
M
Ito
Y
Y
Nakahara
Y
Y
Ogawa
T
T
D002240:Carbohydrate Sequence; D006028:Glycosphingolipids / Q000138:chemical synthesis*; D008969:Molecular Sequence Data; D013237:Stereoisomerism; D014908:Triticum
D006028:Glycosphingolipids; C013869:ceramide dihexoside