Rupture of ectopic pregnancy following disappearance of serum beta subunit of hCG.
The introduction of sensitive assays for the beta subunit of hCG (beta-hCG) and improved ultrasound technology for diagnosis and monitoring of ectopic pregnancy have changed the clinical approach to the management of ectopic pregnancy. Only a few reports have been published of patients with ectopic gestation and negative serum beta-hCG levels. None of these described rupture of ectopic pregnancy following the decline of beta-hCG levels to below 10 mIU/mL. We describe a case of ectopic pregnancy, managed expectantly, in which rupture and hemoperitoneum occurred after the decline of beta-hCG levels to below 10 mIU/mL.
Department of Obstetrics and Gynecology, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel.
D
D
Hochner-Celnikier
M
M
Ron
R
R
Goshen
D
D
Zacut
G
G
Amir
S
S
Yagel
D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood*; D018997:Chorionic Gonadotropin, beta Subunit, Human; D005260:Female; D006465:Hemoperitoneum / Q000209:etiology; D006801:Humans; D010446:Peptide Fragments / Q000097:blood*; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000097:blood* / Q000175:diagnosis; D012422:Rupture, Spontaneous
D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments