Factors affecting kidney transplantation success.
Forty percent of kidney transplants function for more than 10 years, allowing their recipients a lifestyle that is dialysis-free. Causes of success or failure of transplants are grouped into patient-related immunogenetic, pre- and perioperative, and postoperative factors. Some factors turn out to be interdependent, eg, the effect of pretransplantation transfusion and ethnic mismatch or donor age and ischemia; thus, no single analysis can be considered definitive. However, in documenting recent evidence gleaned predominantly from multifactorial analysis, we hope to assess relative risks associated with clinically important factors more accurately.
Bradley
B A
BA
University of Bristol, Department of Transplantation Sciences, Medical School Unit, Southmead Centre for Medical Education, Southmead Health Services, Westbury-on Trym, UK.
D000367:Age Factors; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology*; D012737:Sex Factors