[Effects of nifuroxazide (Ercefuryl), trimethoprim-sulfamethoxazole and bactisubtil in acute diarrhea].
The clinical effects of Nifuroxasid (N), Trimetoprim sulphametoxasol (TS) and Bactisubtil (B) on bacillar dysentery and alimentary toxicoinfections in the patients treated at the Clinic from January 1984 to the end of December 1989 have been analysed. According to the clinical signs, patients have been divided in ten categories of light, mild and heavy forms. In total, 329 cases of bacillar dysentery and 89 cases of alimentary toxicoinfections have been analysed. The following was established: A. Bacilar dysentery: the fastest normalization of the stool was achieved with N in every clinical form (averages 2.2, 3.5 and 4.05 days). With TS the effects were slower (3.0, 3.9 and 4.4 days), but the slowest normalization was recorded with B (3.4, 4.6 and 5.4 days). However, with TS, some Shigella strains showed resistance (in 23 out of 94 antibiograms), which diminished the effects. B. Alimentary toxicoinfections were treated only with N and B, since these forms of diarrhea caused by toxigenic factors were milder. Better results were achieved with N in this case as well.
Klinika za infektivne bolesti i febrilna stanja, Klinicki centar Sarajevo.
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Bulbulović-Telalbasić
D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001412:Bacillus subtilis; D001685:Biological Factors / Q000627:therapeutic use*; D003967:Diarrhea / Q000188:drug therapy* / Q000209:etiology; D004405:Dysentery, Bacillary / Q000150:complications / Q000188:drug therapy; D005517:Foodborne Diseases / Q000150:complications / Q000188:drug therapy; D006801:Humans; D062385:Hydroxybenzoates / Q000627:therapeutic use*; D009581:Nitrofurans / Q000627:therapeutic use*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D000890:Anti-Infective Agents; D001685:Biological Factors; D062385:Hydroxybenzoates; D009581:Nitrofurans; C089800:bactisubtil; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; C013150:nifuroxazide
Efekti djelovanja nifuroksazida (Ercefuryl), trimetoprim sulfametoksazola i bactisuptila u akutnih dijareja.