[Level of estradiol and progesterone in blood serum during the menstrual cycle in woman with acute hepatitis b].
The study was aimed at the determination of blood serum levels of the ovarian hormones (estradiol and progesterone) in women during the first menstrual cycle occurring in the course of hospitalization because of the acute viral hepatitis of type B, and in the same women during the first menstrual cycle occurring in the course of early convalescence after leaving the hospital. The observed group consisted of 20 women of age between 18 and 35 years treated because of acute hepatitis without coexisting diseases including gynecological ailments. All the women had a regular 28-day menstrual cycle. Twenty healthy women served as a control group. The blood serum concentrations of estradiol and progesterone were determined in all the subjects on 6-th, 12-th, 14-th, 18-th and 22-nd day of the menstrual cycle by RIA method using the ready made reagent kits. A significant decrease in the mean value of estradiol was found in the group of sick women as compared to the control group and to the same group of women in the course of early convalescence. On the other hand the value obtained during the first menstrual cycle after discharge from the hospital did not differ from that observed in healthy women. Mean value of blood serum progesterone concentration was higher in sick women than those in the control group and in the same women during convalescence all the time except on the 22-nd day of the cycle. These values did not differ significantly when comparing the group of sick women during convalescence and the control group.(ABSTRACT TRUNCATED AT 250 WORDS)
Katedra i Klinika Chorób Zakaźnych AM w Lublinie.
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Krawczuk
D000208:Acute Disease; D000328:Adult; D016022:Case-Control Studies; D003289:Convalescence; D004958:Estradiol / Q000097:blood*; D005260:Female; D006509:Hepatitis B / Q000097:blood*; D006801:Humans; D008597:Menstrual Cycle / Q000097:blood*; D011374:Progesterone / Q000097:blood*; D011863:Radioimmunoassay
D011374:Progesterone; D004958:Estradiol
Poziom estradiolu i progesteronu w surowicy krwi, w cyklu menstruacyjnym kobiet chorych na ostre wirusowe zapalenie watroby B.