Multiple endocrine adenopathy.
The syndromes of multiple endocrine adenopathy (MEA) have associated endocrine abnormalities that are similar to the clinical syndromes based in the same hyperfunctions of parathyroid, pancreatic islets, thyroid C-cell and chromaffin tissue seen in sporadic cases. The natural history, histopathology and management of these problems when they occur in the hereditary MEA syndromes differ in significant and instructive ways over the isolated disorders. These differences and similarities of MEA adenopathies were discussed at an international conference, with the suggestion that the MEA syndromes afford opportunity to investigate regulation and control of pathogenesis in surgical endocrinological syndromes.
Geelhoed
G W
GW
Department of Surgery, George Washington University Medical Center, Washington, DC.
Van Heerden
J A
JA
Hamberger
B
B
Johansson
H
H
Roher
H D
HD
Indyk
J
J
D000328:Adult; D005260:Female; D006801:Humans; D009377:Multiple Endocrine Neoplasia / Q000601:surgery