Radiographic, haematological, and biochemical findings in a fetus with Caffey disease.
An early case of prenatal Caffey disease is reported. Ultrasound examination performed at 20 weeks showed major angulations of long bones, but both ultrasound scan and X-rays failed to make the differential diagnosis between Caffey disease and lethal osteogenesis imperfecta. A cordocentesis allowed us to find important biological abnormalities. The pregnancy was terminated after the rapid development of hydrops fetalis. The definitive diagnosis of Caffey disease was obtained by special X-ray and pathological study.
Lécolier
B
B
Laboratoire de Biologie Foetale, Hôpital Notre-Dame de Bon-Secours, Paris, France.
Bercau
G
G
Gonzalès
M
M
Afriat
R
R
Rambaud
D
D
Mulliez
N
N
de Kermadec
S
S
D015720:5'-Nucleotidase / Q000097:blood; D000032:Abortion, Therapeutic; D000328:Adult; D001772:Blood Cell Count; D002097:C-Reactive Protein / Q000378:metabolism; D017218:Cordocentesis; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D015160:Hydrops Fetalis / Q000150:complications; D006958:Hyperostosis, Cortical, Congenital / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D007075:Immunoglobulin M / Q000032:analysis; D010013:Osteogenesis Imperfecta / Q000175:diagnosis; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011859:Radiography; D005723:gamma-Glutamyltransferase / Q000097:blood
D007075:Immunoglobulin M; D002097:C-Reactive Protein; D005723:gamma-Glutamyltransferase; D015720:5'-Nucleotidase