MDMA (Ecstasy) precipitation of panic disorder.
The authors describe three patients whose panic disorder began during recreational use of MDMA (Ecstasy) and was subsequently complicated by agoraphobic avoidance that continued autonomously after cessation of the drug. Their panic disorder responded well to serotoninergic antidepressant drugs. Theoretical and practical implications are discussed.
Department of Neurology and Psychiatry, Florence University Medical School, Italy.
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Pallanti
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Mazzi
D015104:3,4-Methylenedioxyamphetamine / Q000009:adverse effects / Q000031:analogs & derivatives*; D000328:Adult; D000379:Agoraphobia / Q000139:chemically induced / Q000188:drug therapy / Q000523:psychology; D000428:Alcohol Drinking / Q000009:adverse effects; D000639:Amitriptyline / Q000627:therapeutic use; D001143:Arousal / Q000187:drug effects; D016666:Fluvoxamine / Q000627:therapeutic use; D006801:Humans; D008297:Male; D018817:N-Methyl-3,4-methylenedioxyamphetamine; D016584:Panic Disorder / Q000139:chemically induced* / Q000188:drug therapy / Q000523:psychology; D012008:Recurrence; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy / Q000523:psychology*; D014191:Tranylcypromine / Q000627:therapeutic use
D000639:Amitriptyline; D014191:Tranylcypromine; D015104:3,4-Methylenedioxyamphetamine; D018817:N-Methyl-3,4-methylenedioxyamphetamine; D016666:Fluvoxamine