Multiple endocrine neoplasia type 2A.
A 40-year-old woman was admitted with complaints of headache, palpitation and diaphoresis. She had undergone right hemithyroidectomy 12 years previously. Histological reexamination of the operative specimen revealed a medullary thyroid carcinoma. Abdominal ultrasonography, CT scan and angiography showed bilateral adrenal tumors. Serum catecholamine levels in both adrenal veins were high. Based on these data, bilateral adrenalectomy was performed. Histological examination confirmed the diagnosis of pheochromocytomas. After operation, serum calcitonin and urinary noradrenaline levels were still high. Further examination by 131I-metaiodobenzylguanidine (MIBG) scintigraphy is planned.
Shimizu
H
H
Department of Internal Medicine, Chusei General Hospital, Suzuka, Japan.
Ueda
Y
Y
Makino
K
K
Fujioka
H
H
Hamada
M
M
Kanamaru
M
M
Murata
T
T
Fujioka
M
M
Konishi
T
T
Nakano
T
T
D000310:Adrenal Gland Neoplasms / Q000378:metabolism / Q000473:pathology*; D000328:Adult; D002395:Catecholamines / Q000378:metabolism; D005260:Female; D006801:Humans; D009377:Multiple Endocrine Neoplasia / Q000378:metabolism / Q000473:pathology*; D010673:Pheochromocytoma / Q000378:metabolism / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000473:pathology*
D002395:Catecholamines