South American monkeys in the development and testing of malarial vaccines--a review.
South American Aotus and Saimiri monkeys, which are susceptible to infection with human malarias, have been used to develop models for the testing of human malaria vaccines. Studies indicate that blood-stage and sporozoite vaccines can be tested in these monkeys using appropriate strains of parasites.
Collins
W E
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Malaria Branch, Centers for Disease Control, Atlanta, Georgia 30333.
D000818:Animals; D001029:Aotus trivirgatus / Q000097:blood / Q000276:immunology / Q000469:parasitology*; D001769:Blood / Q000469:parasitology; D009033:Culicidae; D004198:Disease Susceptibility; D005069:Evaluation Studies as Topic; D006801:Humans; D007299:Insect Bites and Stings; D007303:Insect Vectors; D017780:Malaria Vaccines / Q000276:immunology; D016778:Malaria, Falciparum / Q000469:parasitology / Q000517:prevention & control* / Q000635:transmission; D016780:Malaria, Vivax / Q000469:parasitology / Q000517:prevention & control* / Q000635:transmission; D010963:Plasmodium falciparum / Q000254:growth & development / Q000276:immunology / Q000472:pathogenicity*; D010966:Plasmodium vivax / Q000254:growth & development / Q000276:immunology / Q000472:pathogenicity*; D012453:Saimiri / Q000097:blood / Q000276:immunology / Q000469:parasitology*; D013045:Species Specificity; D013156:Splenectomy
D017780:Malaria Vaccines